title: Madelung disease: a rare case associated with gynaecomastia and scrotal involvement.
abstract: Madelung disease is rare, and characterised by accumulation of fatty non-encapsulated tissue in the head, neck, shoulders, and upper extremities. The aetiology is not completely known, but the association with alcohol intake is clear. We present a neglected case that was associated with bilateral asymmetrical gynaecomastia. To the best of our knowledge, this is a pattern of involvement not previously reported. The treatment of choice is lipectomy for severe cases and liposuction for less extensive accumulations of fat.
authors.affiliation: Clinic for Maxillofacial Surgery, Faculty of Stomatology , Belgrade.
authors.forename: Zivorad S
authors.initials: ZS
authors.lastname: Nikolić
authors.forename: Jelena V
authors.initials: JV
authors.lastname: Jeremić
authors.forename: Lazar J
authors.initials: LJ
authors.lastname: Drčić
authors.forename: Zoran B
authors.initials: ZB
authors.lastname: Rakočević
authors.forename: Zoran D
authors.initials: ZD
authors.lastname: Tačević
authors.forename: Katarina V
authors.initials: KV
authors.lastname: Jeremić
authors.forename: Jelena D
authors.initials: JD
authors.lastname: Stojnić
mesh_terms: D000437:Alcoholism / Q000150:complications / Q000175:diagnosis; D005500:Follow-Up Studies; D005832:Genital Diseases, Male / Q000150:complications / Q000175:diagnosis*; D006177:Gynecomastia / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D015187:Lipectomy / Q000379:methods; D008069:Lipomatosis, Multiple Symmetrical / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D008408:Mastectomy / Q000379:methods; D008875:Middle Aged; D035583:Rare Diseases; D018570:Risk Assessment; D012611:Scrotum / Q000503:physiopathology*; D012720:Severity of Illness Index; D012907:Smoking / Q000009:adverse effects; D016896:Treatment Outcome