title: Triple-negative phenotype of poorly-differentiated metaplastic breast carcinoma in a male: an oncological rarity.
abstract: Metaplastic breast carcinoma (MBC) is an extremely rare breast malignancy having highly aggressive clinicopathological behaviour and dismal prognosis. A 75 years old man presented with a painless lump on right side of his chest along with two additional lumps in the ipsilateral axillary and inguinal areas. Microscopic evaluation and immunohistochemistry of trucut tissue biopsies of the lumps and that of mastectomy specimen revealed a triple-negative phenotype of poorlydifferentiated metaplastic breast carcinoma with metastatic deposits to the axillary and inguinal lymph nodes. Exhaustive internet research has revealed only a few case reports of MBC in the men; thus highlighting its absolute oncological rarity.
authors.affiliation: Department of General Surgery, Pakistan Atomic Energy Commission (PAEC) General Hospital, Islamabad. surgeonarehman@yahoo.com
authors.forename: Abdul
authors.initials: A
authors.lastname: Rehman
mesh_terms: D000368:Aged; D001365:Axilla / Q000473:pathology; D001706:Biopsy; D018567:Breast Neoplasms, Male / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008408:Mastectomy; D008679:Metaplasia / Q000473:pathology* / Q000601:surgery; D035583:Rare Diseases; D016896:Treatment Outcome