title: A rare coexistence: drug induced hepatitis and meningitis in association with Ibuprofen.
abstract: Ibuprofen, a commonly used NSAID is reported to be associated with drug induced liver injury. Ibuprofen is also known to be associated with drug-induced meningitis especially in patients with connective tissue disorders. However presentation of hepatitis and meningitis in association with Ibuprofen use in the same individual has never been reported. We present a case of young woman who developed abnormal liver chemistries and neurological symptoms while on Ibuprofen. Her liver biopsy findings were suggestive of drug induced liver injury and cerebrospinal fluid analysis was suggestive of aseptic meningitis. Clinical and biochemical improvement was noted on cessation of Ibuprofen.
authors.affiliation: Division of Gastroenterology and Hepatology, Bronx Lebanon Hospital Center, Affiliated with Albert Einstein College of Medicine, Yeshiva University, Bronx, New York, USA ; Department of Medicine, Bronx Lebanon Hospital Center, Affiliated with Albert Einstein College of Medicine, Yeshiva University, Bronx, New York, USA.
authors.forename: Suresh Kumar
authors.initials: SK
authors.lastname: Nayudu
authors.forename: Shilpa
authors.initials: S
authors.lastname: Kavuturu
authors.forename: Masooma
authors.initials: M
authors.lastname: Niazi
authors.forename: Myrta
authors.initials: M
authors.lastname: Daniel
authors.forename: Anil
authors.initials: A
authors.lastname: Dev
authors.forename: Kavitha
authors.initials: K
authors.lastname: Kumbum
keywords: Hepatitis; Ibuprofen; Meningitis