title: Prolonged moderate-intensity exercise oxygen uptake response following heavy-intensity priming exercise with short- and longer-term recovery.
abstract: This study examines the effects of recovery duration following heavy-intensity "priming" exercise (Hvy) on pulmonary oxygen (O2) uptake (V̇O2p) during subsequent prolonged moderate-intensity exercise (Mod). Nine participants (6 men and 3 women) (27 ± 7 years) each completed 3 repetitions of 2 continuous Mod 1-Hvy-Mod 2 leg-cycling protocols in which Mod 2 lasted 30 min, but was preceded by a recovery duration of either 6 (R6) or 20 (R20) min at 20 W following Hvy; in each case, Mod 1 and Hvy lasted 6 min and were preceded by 6 min at 20 W. V̇O2p, heart rate (HR), and near-infrared spectroscopy (NIRS)-derived muscle deoxygenation ([HHb]) responses were modeled as a monoexponential; additionally, 60-s averages were computed every 6 min in Mod 1 and Mod 2. V̇O2p was elevated (p < 0.05) throughout Mod 2 compared with Mod 1 in both R6 and R20 (by -82 mL·min(-1) or ∼5.0%); this occurred despite a complete recovery of baseline V̇O2p (V̇O2pBsln) following R20. HR and minute ventilation (V̇E), but not [HHb], were also elevated throughout Mod 2. The phase II time constant for V̇O2p (τV̇O2p) was reduced in Mod 2 (22 s (Mod 1), 19 s (Mod 2); p < 0.05), as was the "overshoot" in the normalized [HHb]/O2 uptake ratio (p < 0.05). This study shows that V̇O2p was elevated during Mod following Hvy, regardless of recovery duration; however, a determining role for V̇O2pBsln is precluded. Furthermore, neither V̇O2p, HR, nor V̇E showed any evidence of a readjustment back to no-Hvy conditions during prolonged Mod (p > 0.05). Lastly, regardless of recovery duration, τV̇O2p was reduced to a similar extent with Hvy, likely resulting from an improved matching of local muscle O2 delivery to O2 utilization.
authors.affiliation: a Canadian Centre for Activity and Aging, The University of Western Ontario, London, ON N6A 3K7, Canada.
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Spencer
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Keir
authors.forename: Joshua P
authors.initials: JP
authors.lastname: Nederveen
authors.forename: Juan M
authors.initials: JM
authors.lastname: Murias
authors.forename: John M
authors.initials: JM
authors.lastname: Kowalchuk
authors.forename: Donald H
authors.initials: DH
authors.lastname: Paterson
mesh_terms: D015444:Exercise; D006801:Humans; D010100:Oxygen; D010101:Oxygen Consumption; D012123:Pulmonary Ventilation; D019265:Spectroscopy, Near-Infrared
chemical_list: D010100:Oxygen