title: Characterization of phenolic constituents from ephedra herb extract.
abstract: Nine known compounds: trans-cinnamic acid, catechin, syringin, epicatechin, symplocoside, kaempferol 3-O-rhamnoside 7-O-glucoside, isovitexin 2-O-rhamnoside, herbacetin 7-O-glucoside, and pollenitin B and a new flavonoid glycoside, characterized as herbacetin 7-O-neohesperidoside (1) on the basis of spectroscopic analysis and chemical evidence, were isolated from a traditional crude drug, "Ephedra herb extract". Compound 1 had no effects on HGF-induced motility, whereas herbacetin, which is an aglycone of 1, significantly inhibited it.
authors.affiliation: Department of Pharmacognosy, College of Pharmaceutical Sciences, Matsuyama University, 4-2 Bunkyo-cho, Matsuyama, Ehime 790-8578, Japan. amakura@cc.matsuyama-u.ac.jp
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Amakura
authors.forename: Morio
authors.initials: M
authors.lastname: Yoshimura
authors.forename: Saori
authors.initials: S
authors.lastname: Yamakami
authors.forename: Takashi
authors.initials: T
authors.lastname: Yoshida
authors.forename: Daigo
authors.initials: D
authors.lastname: Wakana
authors.forename: Masashi
authors.initials: M
authors.lastname: Hyuga
authors.forename: Sumiko
authors.initials: S
authors.lastname: Hyuga
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Hanawa
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Goda
mesh_terms: D001565:Benzoates / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002465:Cell Movement / Q000187:drug effects*; D029789:Ephedra / Q000737:chemistry*; D017228:Hepatocyte Growth Factor / Q000494:pharmacology; D006801:Humans; D020835:Medicine, Kampo; D010936:Plant Extracts / Q000737:chemistry*
chemical_list: D001565:Benzoates; C066855:HGF protein, human; D010936:Plant Extracts; D017228:Hepatocyte Growth Factor