title: [Neuromyelitis optica is a frequently seen inflammatory demyelinating disease].
abstract: Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system with autoimmune characteristics. Serum immunoglobulin G autoantibodies have been identified in the majority of NMO patients with the water channel aquaporin-4 (AQP4) as their main target autoantigen. Clinical criteria have defined NMO and NMO-spectrum disease. The clinical features include inflammation of the optic nerve.
authors.affiliation: Neurologisk Afdeling, Sygehus Lillebælt Vejle, Vejle Sygehus, Kabbeltoft 25, 7100 Vejle, Denmark. nasgari@health.sdu.dk
authors.forename: Nasrin
authors.initials: N
authors.lastname: Asgari
authors.forename: Hanne Pernille Bro
authors.initials: HP
authors.lastname: Skejø
authors.forename: Søren Thue
authors.initials: ST
authors.lastname: Lillevang
authors.forename: Egon
authors.initials: E
authors.lastname: Stenager
mesh_terms: D051401:Aquaporin 4 / Q000134:cerebrospinal fluid / Q000276:immunology; D001323:Autoantibodies / Q000134:cerebrospinal fluid / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D008279:Magnetic Resonance Imaging; D009188:Myelitis, Transverse / Q000209:etiology; D009471:Neuromyelitis Optica / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology; D009902:Optic Neuritis / Q000209:etiology
chemical_list: D051401:Aquaporin 4; D001323:Autoantibodies; D007074:Immunoglobulin G