title: Age-related differences in rat multipotent mesenchymal stromal bone marrow cells.
abstract: We studied multipotent mesenchymal stromal cells isolated from the bone marrow of young (1 month) and old (>12 months) rats. The cell cultures derived from old rats were characterized by lower cell yield in the primary culture, lower number of doublings, and reduced colony-forming capacity of precursor cells.
authors.affiliation: Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia.
authors.forename: M P
authors.initials: MP
authors.lastname: Valyushina
authors.forename: L B
authors.initials: LB
authors.lastname: Buravkova
mesh_terms: D000375:Aging; D000818:Animals; D001854:Bone Marrow Cells / Q000502:physiology*; D002454:Cell Differentiation; D049109:Cell Proliferation; D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D059630:Mesenchymal Stem Cells / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar