title: Evaluation of a bladder cancer cluster in a population of criminal investigators with the Bureau of Alcohol, Tobacco, Firearms and Explosives--part 2: the association of cancer risk and fire scene investigation.
abstract: This study evaluated the association of bladder cancer risk and fire scene investigation within a cohort of white male criminal investigators with the United States Bureau of Alcohol, Tobacco, Firearms and Explosives that was found to be at increased risk for bladder cancer. Medical surveillance data were used in a nested case-control study to determine odds ratios (ORs) estimating the relative risk of the cancer associated with post-fire investigation. The study comprised seven bladder cancer cases and 1525 controls. Six of the cases reported holding assignments associated with post-fire investigation. The OR for bladder cancer was 19.01 (95% confidence interval = 1.94-186.39) for those holding any one or more of these assignments for one to four years versus zero years and 12.56 (1.14-138.58) for those holding any one or more of these assignments for five or more years versus zero years. The risk for bladder cancer is significantly elevated for those holding post-fire investigation assignments compared to those not holding these assignments.
authors.affiliation: Federal Occupational Health, United States Department of Health and Human Services, 4550 Montgomery Avenue, Bethesda, MD 20814, USA. sdavis228@comcast.net
authors.forename: Susan R
authors.initials: SR
authors.lastname: Davis
authors.forename: Xuguang
authors.initials: X
authors.lastname: Tao
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Bernacki
authors.forename: Amy S
authors.initials: AS
authors.lastname: Alfriend
authors.forename: Mark E
authors.initials: ME
authors.lastname: Delowery
mesh_terms: D000328:Adult; D000367:Age Factors; D002295:Carcinoma, Transitional Cell / Q000453:epidemiology*; D016022:Case-Control Studies; D016000:Cluster Analysis; D015331:Cohort Studies; D005390:Fires; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D016495:Police; D012307:Risk Factors; D064424:Tobacco Use / Q000453:epidemiology; D014481:United States / Q000453:epidemiology; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology*