title: Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.
abstract: Placebo controlled double-blinded, prospectively randomized clinical trial with 17 patients (11 verum, 5 placebo) for evaluation of cellulite treatment with Acoustic Wave Therapy, (AWT(®)) was performed. The patients were treated once a week for 7 weeks, a total of 8 treatments with the D-ACTOR(®) 200 by Storz Medical AG. Data were collected at baseline, before 8th treatment, at 1 month (follow-up 1) and at 3 months (follow-up 2) after the last treatment with a patients' questionnaire, weight control, measurement of circumference and standardized photography. Treatment progress was further documented using a specially designed 3D imaging system (SkinSCAN(3D), 3D-Shape GmbH) providing an objective measure of cellulite (primary efficacy criteria). Patient's questionnaire in the verum group revealed an improvement in number and depth of dimples, skin firmness and texture, in shape and in reduction of circumference. The overall result (of skin waviness, Sq and Sz, surface and volume of depressions and elevations, Vvv and Vmp) at two follow-up visits indicates a more than medium sized superiority (MW = 0.6706) and is statistically significant (pWei-Lachin = 0.0106). The placebo group revealed no statistical significance. No side effects were seen. This indicates the efficacy and safety of AWT(®) for patients with cellulite.
authors.affiliation: Praxis und Laserzentrum, Haydnplatz 4, A-6020 Insbruck, Austria. ordination@russe.at
authors.forename: Katharina
authors.initials: K
authors.lastname: Russe-Wilflingseder
authors.forename: Katharina
authors.initials: K
authors.lastname: Russe-Wilfingsleder
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Russe
authors.forename: Johannes C
authors.initials: JC
authors.lastname: Vester
authors.forename: Gerd
authors.initials: G
authors.lastname: Haller
authors.forename: Pavel
authors.initials: P
authors.lastname: Novak
authors.forename: Alexander
authors.initials: A
authors.lastname: Krotz
mesh_terms: D000328:Adult; D003357:Cosmetic Techniques; D004311:Double-Blind Method; D005260:Female; D019220:High-Energy Shock Waves; D006801:Humans; D021621:Imaging, Three-Dimensional; D008875:Middle Aged; D010919:Placebos; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D050151:Subcutaneous Fat / Q000473:pathology*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D010919:Placebos