title: Mesothelioma of the tunica vaginalis. Case report.
abstract: OBJECTIVE
  To report a case of a mesothelioma of the tunica vaginalis and to review the published literature. METHODS / RESULTS: A 61-year-old patient complained of one-month increase of right scrotum size with pain. An ultrasound showed a right hydrocele with a mass attached to the tunica vaginalis. He didn't refer any urological history or known exposure to asbestos. Blood levels of tumor markers (alpha-fetoprotein and beta-HCG) were within normal limits. We performed a radical inguinal orchiectomy with an en-bloc resection of the tunica vaginalis. The pathology described a potentially malignant biphasic mesothelioma. The patient has remained asymptomatic with negative extension studies after 10 years of follow up.
  
  
  CONCLUSIONS
  Paratesticular mesotheliomas are rare tumors (approximately 250 cases reported )with uncertain etiology (only 30-40% are associated with asbestos exposure). The age range is between 50-70 years. Its presentation is usually as a scrotal mass with recurrent reactive hydrocele, which may delay early diagnosis. During surgery, intraoperative biopsy is recommended. It is important to do a differential diagnosis with other benign diseases. Treatment is only curative in early stages with radical orchidectomy and resection in-block of the tunica vaginalis. Despite being multidisciplinary, it is not curative in most cases due to rapid local and distant spread.
authors.affiliation: Service of Urology, Complexo Hospitalario Universitario da Coruña, La Coruña, Spain. drbustomartin@gmail.com
authors.forename: Luis
authors.initials: L
authors.lastname: Busto Martin
authors.forename: Paula
authors.initials: P
authors.lastname: Portela Pereira
authors.forename: Felipe
authors.initials: F
authors.lastname: Sacristan Lista
authors.forename: Lusi
authors.initials: L
authors.lastname: Busto Castañon
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008654:Mesothelioma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009919:Orchiectomy; D012611:Scrotum / Q000473:pathology* / Q000601:surgery; D006848:Testicular Hydrocele / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D013736:Testicular Neoplasms / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor