title: Interaction of dihydromyricetin and alpha-amylase.
abstract: The interaction of dihydromyricetin (DMY) and alpha-amylase was investigated. The complex formed between DMY and alpha-amylase resulted in decreased antioxidant activity of DMY and the catalytic activity of the enzyme, as well as efficient quenching of the intrinsic fluorescence of alpha-amylase. An alpha-amylase molecule provides one binding site for a DMY molecule. These results will be useful for exploiting this compound to combat diseases efficiently.
authors.affiliation: College of Light Industry and Food Science, South China University of Technology, Guangzhou 510640, PR China.
authors.forename: Lei
authors.initials: L
authors.lastname: Chen
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
authors.forename: Qingyi
authors.initials: Q
authors.lastname: Wei
authors.forename: Zhengxiang
authors.initials: Z
authors.lastname: Ning
authors.forename: Erdong
authors.initials: E
authors.lastname: Yuan
mesh_terms: D001665:Binding Sites; D044948:Flavonols / Q000737:chemistry* / Q000378:metabolism*; D000516:alpha-Amylases / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D044948:Flavonols; D000516:alpha-Amylases; C472036:dihydromyricetin