title: Melanoma arising in chronic ulceration associated with lymphoedema.
abstract: Chronic ulceration can be complicated by development of a malignancy. The most frequent associated malignances are squamous cell carcinoma and basal cell carcinoma, although melanoma, leiomyosarcoma and adenocarcinoma are less commonly seen. Chronic lymphoedema may also predispose to development of some malignancies, including lymphangiosarcoma, squamous cell carcinoma and Kaposi's sarcoma. Here, we report the case of a 77-year-old man with primary lymphoedema, who developed melanoma in a chronic foot ulcer of 60 years' duration. The patient underwent wide excision for the melanoma, and remains free from metastases at 1-year follow up.
authors.affiliation: Department of Dermatology, Ege University Medical Faculty, Izmir, Turkey. bengugerceker@yahoo.com
authors.forename: B G
authors.initials: BG
authors.lastname: Turk
authors.forename: A
authors.initials: A
authors.lastname: Bozkurt
authors.forename: B
authors.initials: B
authors.lastname: Yaman
authors.forename: F
authors.initials: F
authors.lastname: Ozdemir
authors.forename: I
authors.initials: I
authors.lastname: Unal
mesh_terms: D000368:Aged; D002908:Chronic Disease; D016523:Foot Ulcer / Q000150:complications*; D006801:Humans; D008209:Lymphedema / Q000150:complications* / Q000601:surgery; D008297:Male; D008545:Melanoma / Q000209:etiology* / Q000601:surgery; D017169:Neoplasms, Post-Traumatic / Q000209:etiology* / Q000601:surgery; D012878:Skin Neoplasms / Q000209:etiology* / Q000601:surgery; D013530:Surgical Wound Infection / Q000150:complications*