title: [The outbreak of focal therapy for localized prostate cancer management].
abstract: These last years, focal therapy is emerging as an intermediate management technique between radical approaches (radical prostatectomy, external beam radiation and brachytherapy) and active surveillance to manage some early stage prostate cancer. Different energy modalities are currently being developed. Prostatic tumour destruction can be achieved with different energies: freezing effect for cryotherapy, thermal effect using focalized ultrasound for HIFU and using thermal effect of light for FLA, and activation of a photosensitizer by light for PDT. Those techniques carry a low morbidity but clinical experience is limited regarding to oncologic outcome. Prospective clinical trials are needed to highlight the full potential of this promising treatment modality.
authors.affiliation: Service d'urologie, CHU de Lille, université Litle-Nord de France, 59000 Lille, France. bozzini_gregory@yahoo.fr
authors.forename: Grégory
authors.initials: G
authors.lastname: Bozzini
authors.forename: Pierre
authors.initials: P
authors.lastname: Colin
authors.forename: Nacim
authors.initials: N
authors.lastname: Betrouni
authors.forename: Adil
authors.initials: A
authors.lastname: Ouzzane
authors.forename: Philippe
authors.initials: P
authors.lastname: Puech
authors.forename: Arnauld
authors.initials: A
authors.lastname: Villers
mesh_terms: D055011:Ablation Techniques; D006801:Humans; D008297:Male; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000601:surgery*