title: Whole body vibration as a safe exercise training method induces no impaired alterations on rat plasma antioxidant biomarkers.
abstract: Whole body vibration (WBV) has been regarded as an exercise training method and as a non-pharmacological supportive treatment option appearing to be efficient in chronic disease conditions, such as bone disorders and for cardio-respiratory fitness. Since, data on the safety and efficacy of vibration on oxidative stress parameters are lacking, it was decided to assess the effects of WBV on the plasma antioxidant biomarkers in adult male Wistar rat model.
  
  
  METHODS
  Male Wistar rats weighing 140-180 g, were divided into control and vibration group. Vibration training consisted of vertical sinusoidal whole body vibration for 8 weeks, followed by blood collection.
  
  
  RESULTS
  The vibrated rats weighed more than the control group (1353.0 ± 21.0 vs. 157.0 ± 36.0g, P < 0.048). The plasma Cu and Zn concentrations, vitamin C, uric acid, the activities of antioxidant enzymes, total antioxidant capacity, and malondialdehyde (MDA) levels were similar in the vibration group. No major differences was observed for selected plasma antioxidant parameters .
  
  
  CONCLUSIONS
  The potential effects of physiological responses of WBV on several physiological systems are without deteriorations concerning plasma antioxidant status.
authors.affiliation: Baqiyatallah (a.s.) University of Medical Sciences Exercise Physiology Research Center & Health School Tehran Iran.
authors.forename: M R
authors.initials: MR
authors.lastname: Naghii
authors.forename: M
authors.initials: M
authors.lastname: Hedayati
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D015415:Biomarkers / Q000097:blood*; D008297:Male; D018384:Oxidative Stress; D051381:Rats; D017208:Rats, Wistar; D014732:Vibration
chemical_list: D000975:Antioxidants; D015415:Biomarkers