title: Click Reaction-Mediated Functionalization of Near-Infrared Pyrrolopyrrole Cyanine Dyes for Biological Imaging Applications.
abstract: A clickable pyrrolopyrrole cyanine (PPCy) dye was synthesized by incorporating an alkyne moiety, followed by click reaction with azide-functionalized molecules of different polarities. The clickable dyes are readily amenable to labelling diverse molecules and exhibit an exceptionally high photostability and an impressive fluorescence quantum yield.
authors.affiliation: Department of Radiology, Optical Radiology Laboratory, Washington University School of Medicine, 4525 Scott Avenue, Saint Louis, MO 63108, USA. ; Tel: 314-362-8599.
authors.forename: Mingzhou
authors.initials: M
authors.lastname: Zhou
authors.forename: Xuan
authors.initials: X
authors.lastname: Zhang
authors.forename: Mingfeng
authors.initials: M
authors.lastname: Bai
authors.forename: Duanwen
authors.initials: D
authors.lastname: Shen
authors.forename: Baogang
authors.initials: B
authors.lastname: Xu
authors.forename: Jeffery
authors.initials: J
authors.lastname: Kao
authors.forename: Ge
authors.initials: G
authors.lastname: Xia
authors.forename: Samuel
authors.initials: S
authors.lastname: Achilefu