title: Autoimmunity in inflammatory bowel disease: a case of ulcerative colitis with diabetes mellitus, autoimmune hepatitis and autoimmune hypothyroidism.
abstract: Ulcerative colitis (UC) is a form of inflammatory bowel disease, which occasionally can be associated with autoimmune disorders. Herein, a two-year-old male infant with UC under sulfasalazine therapy is presented, who consequently developed type I diabetes mellitus, autoimmune hepatitis and autoimmune hypothyroidism. Although presence of concurrent autoimmune diseases with UC is a rare condition, it could highlight the role of immune-related mechanisms as a pathogenesis of disease.
authors.affiliation: Pediatrics Center of Excellence, Children's Medical Center, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. rezaei_nima@yahoo.com.
authors.forename: Mehri
authors.initials: M
authors.lastname: Najafi
authors.forename: Mohammad Mahdi
authors.initials: MM
authors.lastname: Zamani
authors.forename: Nima
authors.initials: N
authors.lastname: Rezaei
authors.forename: Mozhgan
authors.initials: M
authors.lastname: Sabbaghian
mesh_terms: D015551:Autoimmunity / Q000276:immunology*; D003093:Colitis, Ulcerative / Q000150:complications / Q000276:immunology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000276:immunology; D005500:Follow-Up Studies; D050031:Hashimoto Disease / Q000150:complications* / Q000276:immunology; D019693:Hepatitis, Autoimmune / Q000150:complications* / Q000276:immunology; D006801:Humans; D007223:Infant; D015212:Inflammatory Bowel Diseases / Q000150:complications / Q000276:immunology; D008297:Male; D013967:Thyroiditis, Autoimmune