title: Disparities in uptake pattern of (123)I-MIBG, (18)F-FDG, and (99m)Tc-MDP within the same primary neuroblastoma.
abstract: We report an unusual case of primary neuroblastoma in an 11-year-old girl. The superior portion of the tumor accumulated I-MIBG, Tc-MDP, and F-FDG. In contrast, the inferior portion of the tumor showed no abnormal F-FDG or Tc-MDP uptake, which usually indicates tumor necrosis. This inferior portion of the tumor, however, had intense I-MIBG activity, consistent with viable tumor rather than tumor necrosis.
authors.affiliation: From the Department of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
authors.forename: Ion
authors.initials: I
authors.lastname: Codreanu
authors.forename: Hongming
authors.initials: H
authors.lastname: Zhuang
mesh_terms: D019797:3-Iodobenzylguanidine / Q000378:metabolism*; D001692:Biological Transport; D002648:Child; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D006801:Humans; D009447:Neuroblastoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism*; D049268:Positron-Emission Tomography; D013669:Technetium Tc 99m Medronate / Q000378:metabolism*; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18; D019797:3-Iodobenzylguanidine; D013669:Technetium Tc 99m Medronate