title: Synephrine-containing dietary supplement precipitating apical ballooning syndrome in a young female.
abstract: Apical ballooning syndrome (ABS) is a unique reversible cardiomyopathy that is frequently precipitated by emotional or physical stress. In addition, the few drugs reported to precipitate ABS were either illegal or strictly controlled for medical use. This paper reports a case of ABS precipitated by a dietary supplement. Our case accentuates the potential risk of dietary supplements containing synephrine, which is uncontrolled and available to the general public. Therefore, the Korea Food and Drug Administration should regulate these dietary supplements, and warn healthcare workers and the general public of the potential hazards of the indiscriminate abuse of dietary supplements.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Hyemoon
authors.initials: H
authors.lastname: Chung
authors.forename: Sung Woo
authors.initials: SW
authors.lastname: Kwon
authors.forename: Tae Hoon
authors.initials: TH
authors.lastname: Kim
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Yoon
authors.forename: Dae Won
authors.initials: DW
authors.lastname: Ma
authors.forename: Yoo Mi
authors.initials: YM
authors.lastname: Park
authors.forename: Bum-Kee
authors.initials: BK
authors.lastname: Hong
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000009:adverse effects*; D019587:Dietary Supplements / Q000009:adverse effects; D005260:Female; D006801:Humans; D013578:Synephrine / Q000009:adverse effects*; D054549:Takotsubo Cardiomyopathy / Q000139:chemically induced*; D055815:Young Adult
chemical_list: D000316:Adrenergic alpha-Agonists; D013578:Synephrine
keywords: Dietary supplements; Synephrine; Takotsubo cardiomyopathy