title: Compensation phenomena found in Acidithiobacillus ferrooxidans after starvation stress.
abstract: Acidithiobacillus ferrooxidans showed the compensate growth and oxidation after re-feeding with sufficient ferrous materials after starvation. Compensatory phenomena were first detected in chemoautotrophic organisms. Starvation stress of Acidithiobacillus ferrooxidans was achieved via culturing in low concentrations of iron. During compensation, growth and ferrous oxidation took place faster than in controls. In addition, some genes related to ferrous oxidation (such as rus) and carbon assimilation (cbbR, csoS3) were expressed in different patterns in the low energy environments. Their expression patterns can account for this increased growth and oxidation. Other groups of genes (cspAB, feoAB, fur) were suppressed in response to starvation stress. The presence of pyrite and joint cold stress can render compensation nearly undetectable. This may be why the compensation phenomena observed under these conditions was not the same as that observed under single starvation stress conditions. Gene expression reflected a possible mechanism of tolerance to starvation in Acidithiobacillus ferrooxidans, which would allow the organism to adapt and survive in ferrous-limited environments.
authors.affiliation: Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, P.R. China; Centers for Disease Control and Prevention of Changzhou, Changzhou, P.R. China; State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Nanjing, P.R. China.
authors.forename: Bowen
authors.initials: B
authors.lastname: Tu
authors.forename: Juan
authors.initials: J
authors.lastname: Li
authors.forename: Yueshuai
authors.initials: Y
authors.lastname: Guo
authors.forename: Xuejiang
authors.initials: X
authors.lastname: Guo
authors.forename: Xiancai
authors.initials: X
authors.lastname: Lu
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Han
mesh_terms: D042763:Acidithiobacillus / Q000254:growth & development / Q000378:metabolism / Q000502:physiology* / Q000528:radiation effects; D058639:Cold-Shock Response; D020869:Gene Expression Profiling; D015964:Gene Expression Regulation, Bacterial; D007501:Iron / Q000378:metabolism*; D053858:Metabolic Networks and Pathways; D010084:Oxidation-Reduction; D013312:Stress, Physiological
chemical_list: D007501:Iron
keywords: Acidithiobacillus ferrooxidans; Compensatory growth; Oxidation of ferrous; Starvation stress