title: [Clinical significance of new classification of gastroenteropancreatic neuroendocrine neoplasms].
abstract: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a group of tumors derived from diffuse neuroendocrine cells of the digestive system. All GEP-NEN shave potential malignancy. According to the WHO classification (2010), GEP-NENs can be divided into well differentiated neuroendocrine tumor (NET) and poorly differentiated neuroendocrine carcinoma (NEC). GEP-NEN scan be grouped into three grades: G1 , G2 and G3. The new WHO classification unifies the diagnostic terms and avoids the confusion of the nomenclature and classification of GEP-NENs,which is the foundation of clinical treatment and prognostic estimation.
authors.affiliation: Department of Pathology, Fudan University Cancer Center,Shanhai, China. xiongzengzhu@yahoo.com.cn
authors.forename: Xiong-zeng
authors.initials: XZ
authors.lastname: Zhu
mesh_terms: D005770:Gastrointestinal Neoplasms / Q000145:classification*; D006801:Humans; D018358:Neuroendocrine Tumors / Q000145:classification*; D010190:Pancreatic Neoplasms / Q000145:classification*