title: A label-free amplified fluorescence DNA detection based on isothermal circular strand-displacement polymerization reaction and graphene oxide.
abstract: A label-free fluorescent DNA biosensor has been presented based on isothermal circular strand-displacement polymerization reaction (ICSDPR) combined with graphene oxide (GO) binding. The proposed method is simple and cost-effective with a low detection limit of 4 pM, which compares favorably with other GO-based homogenous DNA detection methods.
authors.affiliation: State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, PR China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Li
authors.forename: Wenping
authors.initials: W
authors.lastname: Zhu
authors.forename: Jinwen
authors.initials: J
authors.lastname: Zhang
authors.forename: Jianhui
authors.initials: J
authors.lastname: Jiang
authors.forename: Guoli
authors.initials: G
authors.lastname: Shen
authors.forename: Ruqin
authors.initials: R
authors.lastname: Yu
mesh_terms: D015374:Biosensing Techniques / Q000191:economics / Q000379:methods*; D003362:Cost-Benefit Analysis; D004247:DNA / Q000032:analysis* / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D057230:Limit of Detection; D010087:Oxides / Q000737:chemistry*; D058105:Polymerization; D013050:Spectrometry, Fluorescence; D013696:Temperature
chemical_list: D010087:Oxides; D006108:Graphite; D004247:DNA