title: MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.
authors.forename: Suyoun
authors.initials: S
authors.lastname: Chung
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Nakamura
mesh_terms: D017209:Apoptosis / Q000187:drug effects; D045744:Cell Line, Tumor; D006801:Humans; D009287:Naphthyridines / Q000627:therapeutic use / Q000633:toxicity*; D009369:Neoplasms / Q000188:drug therapy; D014411:Neoplastic Stem Cells / Q000187:drug effects* / Q000378:metabolism; D009479:Neuropeptides / Q000378:metabolism; D010766:Phosphorylation; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use / Q000633:toxicity*; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: C585656:1-(6-(3,5-dichloro-4-hydroxyphenyl)-4-((4-((dimethylamino)methyl)cyclohexyl)amino)-1,5-naphthyridin-3-yl)ethanone; D009287:Naphthyridines; D009479:Neuropeptides; D047428:Protein Kinase Inhibitors; C053386:drebrins; C484610:MELK protein, human; D017346:Protein Serine-Threonine Kinases; D046988:Proteasome Endopeptidase Complex