title: No effects of short-term sleep restriction, in a controlled feeding setting, on lipid profiles in normal-weight adults.
abstract: Short sleep has been associated with cardiovascular risk. The aim of this study was to determine the impact of short-term sleep restriction on lipid profiles and resting blood pressure factors in young, normal-weight individuals (14 men, 13 women). Participants were randomized to five nights of either habitual (9 h) or short (4 h) sleep in a cross-over design separated by a 3-week washout period. There was no sleep × day interaction on lipid profile and blood pressure. Short-term sleep restriction does not alter lipid profiles and resting blood pressure in healthy, normal-weight individuals. The association between short sleep and increased cardiovascular risk reported in the epidemiological literature may be the result of long-term sleep restriction and poor lifestyle choices.
authors.affiliation: New York Obesity Nutrition Research Center, St Luke's/Roosevelt Hospital, New York, NY, USA; Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
authors.forename: Majella
authors.initials: M
authors.lastname: O'Keeffe
authors.forename: Amy L
authors.initials: AL
authors.lastname: Roberts
authors.forename: Michael
authors.initials: M
authors.lastname: Kelleman
authors.forename: Arindam
authors.initials: A
authors.lastname: Roychoudhury
authors.forename: Marie-Pierre
authors.initials: MP
authors.lastname: St-Onge
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D001835:Body Weight; D002318:Cardiovascular Diseases / Q000097:blood / Q000150:complications / Q000209:etiology; D018592:Cross-Over Studies; D004032:Diet; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012890:Sleep / Q000502:physiology; D012892:Sleep Deprivation / Q000097:blood* / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology; D013997:Time Factors
chemical_list: D008055:Lipids
keywords: blood pressure; short sleep; total cholesterol; triglycerides