title: Enhanced transesterification of ethyl ferulate with glycerol for preparing glyceryl diferulate using a lipase in ionic liquids as reaction medium.
abstract: Glyceryl diferulate (DFG) is a water-soluble ester of ferulic acid. A novel ionic liquid (IL) system for enzymatic transesterification of ethyl ferulate (EF) with glycerol to produce DFG was developed. Of three ILs with different anions (BF4 (-), PF6 (-) and TF2N(-)) and cations (BDMIM, OMIM, HMIM, BMIM, and EMIM), EMIMTF2N proved the best using a commercial lipase. It had a significant protective effect against thermal inactivation of the enzyme. High EF conversion (~100 %) and DFG yield (45 %) were achieved using 45 mg enzyme/ml; temperature, 70 °C; reaction time, 12 h.
authors.affiliation: Lipid Technology and Engineering, School of Food Science and Engineering, Henan University of Technology, Lianhua Road, Zhengzhou, 450001, Henan, People's Republic of China. sunshangde@hotmail.com
authors.forename: Shangde
authors.initials: S
authors.lastname: Sun
authors.forename: Fei
authors.initials: F
authors.lastname: Qin
authors.forename: Yanlan
authors.initials: Y
authors.lastname: Bi
authors.forename: Jingnan
authors.initials: J
authors.lastname: Chen
authors.forename: Guolong
authors.initials: G
authors.lastname: Yang
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
mesh_terms: D002109:Caffeic Acids / Q000378:metabolism*; D004795:Enzyme Stability; D004951:Esterification; D005990:Glycerol / Q000378:metabolism*; D052578:Ionic Liquids; D008049:Lipase / Q000737:chemistry / Q000378:metabolism*; D050178:Monoglycerides / Q000378:metabolism*; D013696:Temperature
chemical_list: D002109:Caffeic Acids; D052578:Ionic Liquids; D050178:Monoglycerides; C531553:glyceryl ferulate; C099085:ethyl ferulate; D008049:Lipase; D005990:Glycerol