title: Biotransformation of osthole by Alternaria longipes.
abstract: The biotransformation of osthole (1) by Alternaria longipes was carried out, and five transformed products were obtained in the present research work. Based on their extensive spectral data, the structures of these metabolites were characterized as 4'-hydroxyl-osthole (2), 4'-hydroxyl-2',3'-dihydroosthole (3), 2',3'-dihydroxylosthole (4), osthole-4'-oic acid methyl ester (5), and osthole-4'-oic acid glucuron-1-yl ester (6), respectively. Among them, products 5 and 6 were new compounds.
authors.affiliation: College of Bioengineering, Beijing Polytechnic, China. xiulanxin2011@163.com
authors.forename: Xiu-Lan
authors.initials: XL
authors.lastname: Xin
authors.forename: Pei Pei
authors.initials: PP
authors.lastname: Dong
authors.forename: Gang
authors.initials: G
authors.lastname: Wang
authors.forename: Rong-Gang
authors.initials: RG
authors.lastname: Xi
authors.forename: Dan
authors.initials: D
authors.lastname: Liu
authors.forename: Zhi-Ming
authors.initials: ZM
authors.lastname: Wu
authors.forename: Xian-Ce
authors.initials: XC
authors.lastname: Sun
authors.forename: Rong
authors.initials: R
authors.lastname: Lan
authors.forename: Xiao-Bo
authors.initials: XB
authors.lastname: Wang
mesh_terms: D000528:Alternaria / Q000378:metabolism*; D001711:Biotransformation; D003374:Coumarins / Q000737:chemistry* / Q000378:metabolism; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D003374:Coumarins; C046627:osthol