title: Reninoma: a rare cause of curable hypertension.
abstract: A 25-year-old lady presented with hypertensive encephalopathy. She also had chronic refractory hypertension for the past 7 years. Workup revealed persistent hypokalaemia with metabolic alkalosis suggesting hyperaldosteronism. Hyperaldosteronic states such as renal artery stenosis, Conn's syndrome and Liddle's syndrome were ruled out. Her plasma renin activity was high. Contrast-enhanced CT of the abdomen showed a 1.9×2 cm heterogeneously enhancing lesion in the anterior aspect of the right kidney suggesting a possibility of reninoma. The benign tumour was resected by a nephron-sparing surgery. Histopathology suggested a juxtaglomerular cell tumour. Anti-hypertensive drugs were completely withdrawn postoperatively.
authors.affiliation: Department of Medicine, Indira Gandhi Medical College and Research Institute, Puducherry, India.
authors.forename: Ramanathan
authors.initials: R
authors.lastname: Venkateswaran
authors.forename: Abdoul
authors.initials: A
authors.lastname: Hamide
authors.forename: Lalgudi Narayanan
authors.initials: LN
authors.lastname: Dorairajan
authors.forename: Debdatta
authors.initials: D
authors.lastname: Basu
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000378:metabolism; D000328:Adult; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000209:etiology*; D006973:Hypertension / Q000209:etiology*; D020343:Hypertensive Encephalopathy / Q000209:etiology*; D007680:Kidney Neoplasms / Q000150:complications* / Q000378:metabolism; D012083:Renin / Q000096:biosynthesis*
chemical_list: D012083:Renin