title: Jump-starting the T cells in CLL.
abstract: In this issue of Blood, Shanafelt and colleagues demonstrate that T-cell immune synapse function can be increased in chronic lymphocytic leukemia (CLL), both by reducing tumor burden with immunochemotherapy and by lenalidomide.
authors.affiliation: University of Manitoba.
authors.forename: James B
authors.initials: JB
authors.lastname: Johnston
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D060830:Consolidation Chemotherapy; D006801:Humans; D054992:Immunological Synapses / Q000502:physiology*; D007167:Immunotherapy; D000077269:Lenalidomide; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000628:therapy*; D013601:T-Lymphocytes / Q000276:immunology*; D013792:Thalidomide / Q000008:administration & dosage / Q000031:analogs & derivatives*
chemical_list: D013792:Thalidomide; D000077269:Lenalidomide