title: CAPITO--a web server-based analysis and plotting tool for circular dichroism data.
abstract: BACKGROUND
  Circular dichroism (CD) spectroscopy is one of the most versatile tools to study protein folding and to validate the proper fold of purified proteins. Here, we aim to provide a readily accessible, user-friendly and platform-independent tool capable of analysing multiple CD datasets of virtually any format and returning results as high-quality graphical output to the user.
  
  
  RESULTS
  CAPITO (CD Anaylsis and Plotting Tool) is a novel web server-based tool for analysing and plotting CD data. It allows reliable estimation of secondary structure content utilizing different approaches. CAPITO accepts multiple CD datasets and, hence, is well suited for a wide application range such as the analysis of temperature or pH-dependent (un)folding and the comparison of mutants.
  
  
  BACKGROUND
  http://capito.nmr.fli-leibniz.de.
  
  
  BACKGROUND
  cwiede@fli-leibniz.de or mago@fli-leibniz.de
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Biomolecular NMR Spectroscopy, Leibniz Institute for Age Research-Fritz Lipmann Institute, Beutenbergstr. 11, 07745 Jena, Germany. cwiede@fli-leibniz.de
authors.forename: Christoph
authors.initials: C
authors.lastname: Wiedemann
authors.forename: Peter
authors.initials: P
authors.lastname: Bellstedt
authors.forename: Matthias
authors.initials: M
authors.lastname: Görlach
mesh_terms: D002942:Circular Dichroism / Q000379:methods*; D020407:Internet; D017510:Protein Folding; D017433:Protein Structure, Secondary; D012984:Software