title: [Clinical features and management of acute myositis in idiopathic orbital inflammation].
abstract: Acute myositis is the second most common component of non-specific orbital inflammation. We will describe its clinical features and natural history. This is a retrospective study of 10 cases. The diagnosis of acute myositis was based on clinical and imaging criteria. Our study includes five men and five women. The average age was 35.8 years (17-59 years). Clinical symptoms were: pain increased on eye movement (10/10), diplopia (4/10), proptosis (6/10), visual loss (3/10), lid edema (6/10), conjunctival hyperemia (7/10), anterior scleritis (2/10), episcleritis (2/10), chemosis (4/10), upper lid retraction (1/10), limitation of eye movement (3/10), fundus abnormalities (2/10). Imaging showed thickening of one or more extraocular muscles (10/10). Recovery was complete with anti-inflammatory therapy in six patients. Three patients experienced recurrence, and one patient had a clinical rebound upon tapering the treatment. Acute myositis can be defined by pain on eye movement, signs of inflammation, and extraocular muscle thickening on imaging. If the clinical presentation is typical, histopathological analysis can be deferred but remains necessary in cases of poor response to treatment, chronic duration or suspicion of tumor infiltration. The diagnosis of acute myositis may be suspected in the presence of consistent, well-defined clinical signs. Contiguous inflammation is often associated. Treatment is based on steroids or non-steroidal treatment anti-inflammatory therapy, administered alone or consecutively. Recurrences are frequent but do not alter the final prognosis.
authors.affiliation: Service d'ophtalmologie, université Lille Nord de France, hôpital Claude-Huriez, CHRU de Lille, 2, rue Michel-Polonovski, 59037 Lille cedex, France. Electronic address: emmanuel.halimi@gmail.com.
authors.forename: E
authors.initials: E
authors.lastname: Halimi
authors.forename: R
authors.initials: R
authors.lastname: Rosenberg
authors.forename: O
authors.initials: O
authors.lastname: Wavreille
authors.forename: S
authors.initials: S
authors.lastname: Bouckehove
authors.forename: N
authors.initials: N
authors.lastname: Franquet
authors.forename: P
authors.initials: P
authors.lastname: Labalette
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009916:Orbital Diseases / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D055622:Orbital Myositis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D012008:Recurrence; D012189:Retrospective Studies; D055815:Young Adult
keywords: Acute myositis; Biopsie des muscles oculomoteurs; Extraocular muscle biopsy; Idiopathic orbital inflammation; Inflammation orbitaire non spécifique; Myosite aiguë