title: The impact of prior percutaneous coronary intervention on long-term survival after coronary artery bypass grafting.
abstract: BACKGROUND
  Previous studies examining the influence of prior percutaneous coronary intervention (PCI) on long-term survival after coronary artery bypass grafting (CABG) have reported conflicting results. The purpose of this study was to further examine the influence of prior PCI on long-term survival after CABG at a large tertiary referral heart institute.
  
  
  METHODS
  Long-term survival between 1992 and 2011 was compared in non-emergent CABG cases with and without prior PCI. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model.
  
  
  RESULTS
  A total of 2532 (19%) patients had prior PCI before CABG (n=13,354). The median follow-up for study participants was 8.1 years. The median survival for patients with and without prior PCI was 15 years and 14 years, respectively (p<0.0001). Long-term survival was similar between patients with and without prior PCI after adjusting for age, sex, race, hypertension, coronary artery disease severity, congestive heart failure, and prior stroke (adjusted HR=0.99, 95%CI=0.91-1.06).
  
  
  CONCLUSIONS
  Findings from outcomes research are important in the planning of appropriate postoperative patient care. Our study provides additional evidence that prior PCI is not a significant predictor of long-term survival after CABG.
authors.affiliation: Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, United States. Electronic address: wesoneal85@gmail.com.
authors.forename: Wesley T
authors.initials: WT
authors.lastname: O'Neal
authors.forename: Jimmy T
authors.initials: JT
authors.lastname: Efird
authors.forename: Curtis A
authors.initials: CA
authors.lastname: Anderson
authors.forename: Linda C
authors.initials: LC
authors.lastname: Kindell
authors.forename: Jason B
authors.initials: JB
authors.lastname: O'Neal
authors.forename: T
authors.initials: T
authors.lastname: Bruce Ferguson
authors.forename: W
authors.initials: W
authors.lastname: Randolph Chitwood
authors.forename: Alan P
authors.initials: AP
authors.lastname: Kypson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000401:mortality* / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention; D012189:Retrospective Studies; D013022:South Carolina / Q000453:epidemiology; D015996:Survival Rate; D013997:Time Factors
keywords: CABG; Coronary artery disease; PCI; Survival