title: An indicator of probable semicircular canal dehiscence: ocular vestibular evoked myogenic potentials to high frequencies.
abstract: The n10 component of the ocular vestibular evoked myogenic potential (oVEMP) to sound and vibration stimuli is a crossed response that has enhanced amplitude and decreased threshold in patients with CT-verified superior semicircular canal dehiscence (SSCD). However, demonstrating enhanced VEMP amplitude and reduced VEMP thresholds requires multiple trials and can be very time consuming and tiring for patients, so a specific indicator of probable SCD that is fast and not tiring would be preferred. Here we report a 1-trial indicator: that the oVEMP n10 in response to a very high frequency stimulus (4000 Hz), either air-conducted sound (ACS) or bone conducted vibration (BCV), is such a fast indicator of probable SCD. In 22 healthy subjects, oVEMP n10 at 4000 Hz was not detectable; however, in all 22 CT-verified SSCD patients tested, oVEMP n10 responses were clearly present to 4000 Hz to either ACS or BCV stimuli.
authors.affiliation: MSA ENT Academy Center, Cassino, Italy. lmanzari1962@gmail.com
authors.forename: Leonardo
authors.initials: L
authors.lastname: Manzari
authors.forename: Ann M
authors.initials: AM
authors.lastname: Burgess
authors.forename: Leigh A
authors.initials: LA
authors.lastname: McGarvie
authors.forename: Ian S
authors.initials: IS
authors.lastname: Curthoys
mesh_terms: D000161:Acoustic Stimulation; D001844:Bone Conduction / Q000502:physiology; D015331:Cohort Studies; D006801:Humans; D007759:Labyrinth Diseases / Q000175:diagnosis* / Q000503:physiopathology; D011237:Predictive Value of Tests; D012665:Semicircular Canals / Q000473:pathology* / Q000503:physiopathology; D058585:Vestibular Evoked Myogenic Potentials; D014724:Vestibular Function Tests
keywords: VEMP; cervical VEMP; labyrinth; ocular VEMP; semicircular canal dehiscence; vestibular