title: Immigrants do not transmit tuberculosis more than indigenous patients in Catalonia (Spain).
abstract: BACKGROUND
  Immigrants may not transmit tuberculosis (TB) more than indigenous patients. The objective was to study the prevalence of TB infection among contacts of immigrant and indigenous TB patients and the risk factors associated with latent TB infection.
  
  
  METHODS
  Contacts of TB cases recorded in 2005 and 2006 were surveyed using a standardized Health Department questionnaire. Infections were diagnosed using the tuberculin skin test (TST) (cut-off ≥ 5 mm). The risk of infection was determined by multivariate logistic regression and the adjusted odds ratios (aOR) with the 95% confidence intervals (CI) were calculated.
  
  
  RESULTS
  The study of contacts was completed in 1329 cases of TB. The prevalence of infection was 32.3% (3038/9406) in all contacts, 41.4% in contacts of immigrant cases and 29.2% in contacts of indigenous cases. In the multivariate analysis, immigrant index cases were not associated with an increased risk (aOR = 0.9; 95%CI: 0.8-1.0). The prevalence of TST conversion was 10.0% (296/2969) in all contacts, 11.2% in immigrant contacts and 9.7% in indigenous contacts (p = 0.158).
  
  
  CONCLUSIONS
  Immigrants do not transmit TB more than indigenous TB patients. Infections which may have occurred in the countries of origin of immigrants were detected by the systematic study of contacts.
authors.affiliation: Department of Health, Generalitat of Catalonia, Spain. pere.godoy@gencat.cat
authors.forename: Pere
authors.initials: P
authors.lastname: Godoy
authors.forename: Joan A
authors.initials: JA
authors.lastname: Caylà
authors.forename: Gloria
authors.initials: G
authors.lastname: Carmona
authors.forename: Neus
authors.initials: N
authors.lastname: Camps
authors.forename: Josep
authors.initials: J
authors.lastname: Álvarez
authors.forename: Anna
authors.initials: A
authors.lastname: Rodés
authors.forename: Neus
authors.initials: N
authors.lastname: Altet
authors.forename: Jose-Maria
authors.initials: JM
authors.lastname: Pina
authors.forename: Irene
authors.initials: I
authors.lastname: Barrabeig
authors.forename: Àngels
authors.initials: À
authors.lastname: Orcau
authors.forename: Ignasi
authors.initials: I
authors.lastname: Parron
authors.forename: Miquel
authors.initials: M
authors.lastname: Alsedà
authors.forename: Jaume
authors.initials: J
authors.lastname: March
authors.forename: Núria
authors.initials: N
authors.lastname: Follia
authors.forename: Sofia
authors.initials: S
authors.lastname: Minguell
authors.forename: Àngela
authors.initials: À
authors.lastname: Domínguez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D016358:Contact Tracing / Q000379:methods; D054242:Emigrants and Immigrants / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D055985:Latent Tuberculosis / Q000175:diagnosis / Q000208:ethnology / Q000635:transmission; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D014374:Tuberculin Test; D014376:Tuberculosis / Q000175:diagnosis / Q000208:ethnology / Q000635:transmission*