title: Quantitative analysis of the cochlea using three-dimensional reconstruction based on microcomputed tomographic images.
abstract: The aim of this study was to provide data on various dimensions of the normal cochlea using three-dimensional reconstruction based on high-resolution micro-CT images. The petrous parts of 39 temporal bones were scanned by micro-computed tomography (CT) with a slice thickness of 35 μm. The micro-CT images were used in reconstructing three-dimensional volumes of the bony labyrinth using computer software. The volumes were used to measure 12 dimensions of the cochlea, and statistical analysis was carried out. The dimensions of cochleae varied widely between different specimens. The mean height and length of the cochlea were 3.8 and 9.7 mm, respectively. The angle between the basal and middle turns was slightly larger in males than in females, while none of the other 11 dimensions differed significantly between males and females. The cochlear accessory canals were observed in about half of the cases (51.3%). Correlation analysis among measured items revealed positive correlations among several of the measured dimensions. The present study could investigate the detailed anatomy of the normal cochlea using high-resolution imaging technologies. The results of the present study could be helpful for the precise diagnosis of congenital cochlear malformations and for producing optimized cochlear implants.
authors.affiliation: Department of Anatomy, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Republic of Korea.
authors.forename: Kang-Jae
authors.initials: KJ
authors.lastname: Shin
authors.forename: Ju-Young
authors.initials: JY
authors.lastname: Lee
authors.forename: Jeong-Nam
authors.initials: JN
authors.lastname: Kim
authors.forename: Ja-Young
authors.initials: JY
authors.lastname: Yoo
authors.forename: Chuog
authors.initials: C
authors.lastname: Shin
authors.forename: Wu-Chul
authors.initials: WC
authors.lastname: Song
authors.forename: Ki-Seok
authors.initials: KS
authors.lastname: Koh
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003051:Cochlea / Q000000981:diagnostic imaging*; D003054:Cochlear Implants; D017076:Computer-Aided Design; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D011857:Radiographic Image Interpretation, Computer-Assisted; D013045:Species Specificity; D013701:Temporal Bone / Q000000981:diagnostic imaging; D055114:X-Ray Microtomography; D055815:Young Adult