title: The WU-Minn Human Connectome Project: an overview.
abstract: The Human Connectome Project consortium led by Washington University, University of Minnesota, and Oxford University is undertaking a systematic effort to map macroscopic human brain circuits and their relationship to behavior in a large population of healthy adults. This overview article focuses on progress made during the first half of the 5-year project in refining the methods for data acquisition and analysis. Preliminary analyses based on a finalized set of acquisition and preprocessing protocols demonstrate the exceptionally high quality of the data from each modality. The first quarterly release of imaging and behavioral data via the ConnectomeDB database demonstrates the commitment to making HCP datasets freely accessible. Altogether, the progress to date provides grounds for optimism that the HCP datasets and associated methods and software will become increasingly valuable resources for characterizing human brain connectivity and function, their relationship to behavior, and their heritability and genetic underpinnings.
authors.affiliation: Department of Anatomy & Neurobiology, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA. vanessen@wustl.edu
authors.forename: David C
authors.initials: DC
authors.lastname: Van Essen
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Smith
authors.forename: Deanna M
authors.initials: DM
authors.lastname: Barch
authors.forename: Timothy E J
authors.initials: TE
authors.lastname: Behrens
authors.forename: Essa
authors.initials: E
authors.lastname: Yacoub
authors.forename: Kamil
authors.initials: K
authors.lastname: Ugurbil
mesh_terms: D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology*; D063132:Connectome / Q000379:methods*; D006801:Humans; D008953:Models, Anatomic; D008959:Models, Neurological; D009415:Nerve Net / Q000033:anatomy & histology* / Q000502:physiology*