title: Recombinant proteins: hopes for tissue engineering.
abstract: Proteins constitute a group of key molecules with many applications in tissue engineering. Use of proteins provided from natural sources has several limitations which are overcome by the use of recombinant proteins. So far, the recombinant forms of many proteins with tissue engineering applications have been developed including structural proteins, growth factors and cytokines. This technology has enabled the development of specifically designed proteins such as growth factors with matrix binding domains, and hybrid structural proteins with improved mechanical properties. Recombinant proteins are produced either ex vivo or in vivo, by local gene therapy protocols, and are of medical and economic benefits. Due to the high applicability of recombinant proteins in tissue engineering, it is recommended to include this platform as an infrastructural element in any tissue engineering program.
authors.affiliation: Department of Medical Biotechnology, Cellular and Molecular Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad Morad
authors.initials: MM
authors.lastname: Farajollahi
authors.forename: Sepideh
authors.initials: S
authors.lastname: Hamzehlou
authors.forename: Ahmad
authors.initials: A
authors.lastname: Mehdipour
authors.forename: Ali
authors.initials: A
authors.lastname: Samadikuchaksaraei
keywords: Gene Therapy; Recombinant Proteins; Tissue Engineering