title: Current perspectives on ophthalmic manifestations of childhood rheumatic diseases.
abstract: Inflammatory eye diseases are an important manifestation of many pediatric rheumatologic conditions. Early screening and diagnosis are imperative as these illnesses can not only result in significant visual morbidity but are also an indicator of systemic inflammation. Time to presentation of ocular inflammation varies significantly and can range from many years prior to the onset of systemic symptoms to well after the diagnosis of the rheumatologic disorder. Due to this variability in presentation, careful monitoring by an ophthalmologist is vital to preventing ocular complications and preserving vision. Both local and systemic immunosuppressive medications have been effective in the management of ocular disease. In this review, we will focus on the known ophthalmologic manifestations of common pediatric rheumatologic diseases and discuss recent advances in therapeutic considerations for these conditions.
authors.affiliation: Section of Vitreoretinal Surgery, Department of Ophthalmology, Emory University School of Medicine, 1365B Clifton Rd. NE, Atlanta, GA 30322, USA. neal.palejwala@emory.edu
authors.forename: Neal V
authors.initials: NV
authors.lastname: Palejwala
authors.forename: Steven
authors.initials: S
authors.lastname: Yeh
authors.forename: Sheila T
authors.initials: ST
authors.lastname: Angeles-Han
mesh_terms: D001168:Arthritis / Q000150:complications; D001688:Biological Products / Q000627:therapeutic use; D002648:Child; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D012216:Rheumatic Diseases / Q000150:complications*; D014605:Uveitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D001688:Biological Products; D005938:Glucocorticoids