title: Metal-free synthesis of 2-aminobenzothiazoles via aerobic oxidative cyclization/dehydrogenation of cyclohexanones and thioureas.
abstract: A metal-free process for the synthesis of 2-aminobenzothiazoles from cyclohexanones and thioureas has been developed using catalytic iodine and molecular oxygen as the oxidant under mild conditions. Various 2-aminobenzothiazoles, 2-aminonaphtho[2,1-d]thiazoles, and 2-aminonaphtho[1,2-d]thiazoles were prepared via this method in satisfactory yields.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, PR China.
authors.forename: Jinwu
authors.initials: J
authors.lastname: Zhao
authors.forename: Huawen
authors.initials: H
authors.lastname: Huang
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.forename: Huoji
authors.initials: H
authors.lastname: Chen
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
mesh_terms: D052160:Benzothiazoles / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D003512:Cyclohexanones / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*; D008670:Metals; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D013844:Thiazoles / Q000737:chemistry*; D013890:Thiourea / Q000737:chemistry*
chemical_list: D052160:Benzothiazoles; D003512:Cyclohexanones; D008670:Metals; D013844:Thiazoles; D007455:Iodine; D013890:Thiourea; D010100:Oxygen