title: Resistance exercise combined with essential amino acid supplementation improved walking ability in elderly people.
abstract: We investigated the effects of resistance exercise combined with essential amino acid supplementation on psoas major muscle (PMM) hypertrophy and walking ability in elderly individuals. Twenty-nine healthy elderly individuals were assigned to 3 groups: (1) E (exercise), (2) A3 (exercise combined with 3.0 g of essential amino acid supplementation), and (3) A6 (exercise combined with 6.0 g of essential amino acid supplementation). To evaluate walking ability, the participants underwent the following 3 types of tests: the (1) 10-meter walk (10-W), (2) 10-meter walk involving crossing of obstacles (10-W + O), and (3) 6-minute walk (6M-W) tests. The 6-month training program resulted in significant PMM hypertrophy in all groups independent of amino acid supplementation. The extent of hypertrophy in the participants who took amino acids was dose-dependent, although the differences were not significant. Groups A3 and A6 demonstrated improvements in the 10-W and 10-W + O tests, whereas no improvement was observed in group E, regardless of PMM hypertrophy. Furthermore, group A6 showed an improvement in the 6M-W test. These results suggest that our training program causes PMM hypertrophy, whereas the training program combined with essential amino acid supplementation improves walking ability.
authors.affiliation: The University of Tokyo Laboratory of Tissue Plasticity Science, Department of Life Sciences, Graduate School of Arts and Sciences Tokyo Japan Waseda University Future Institute for Sport Sciences Tokyo Japan 3-8-1 Komaba, Meguro-ku 153-8902 Tokyo Japan.
authors.forename: Shigeo
authors.initials: S
authors.lastname: Kawada
authors.forename: Y
authors.initials: Y
authors.lastname: Okamoto
authors.forename: K
authors.initials: K
authors.lastname: Ogasahara
authors.forename: S
authors.initials: S
authors.lastname: Yanagisawa
authors.forename: M
authors.initials: M
authors.lastname: Ohtani
authors.forename: K
authors.initials: K
authors.lastname: Kobayashi
mesh_terms: D000368:Aged; D000596:Amino Acids / Q000008:administration & dosage*; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D008297:Male; D016658:Psoas Muscles / Q000187:drug effects*; D055070:Resistance Training; D016138:Walking
chemical_list: D000596:Amino Acids