title: Process of prototyping coronary stents from biodegradable Fe-Mn alloys.
abstract: Biodegradable stents are considered to be a recent innovation, and their feasibility and applicability have been proven in recent years. Research in this area has focused on materials development and biological studies, rather than on how to transform the developed biodegradable materials into the stent itself. Currently available stent technology, the laser cutting-based process, might be adapted to fabricate biodegradable stents. In this work, the fabrication, characterization and testing of biodegradable Fe-Mn stents are described. A standard process for fabricating and testing stainless steel 316L stents was referred to. The influence of process parameters on the physical, metallurgical and mechanical properties of the stents, and the quality of the produced stents, were investigated. It was found that some steps of the standard process such as laser cutting can be directly applied, but changes to parameters are needed for annealing, and alternatives are needed to replace electropolishing.
authors.affiliation: IJN-UTM Cardiovascular Engineering Center & Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Johor Bahru, 81310, Malaysia; Laboratory for Biomaterials and Bioengineering, Department of Mining, Metallurgical and Materials Engineering & University Hospital Research Centre, Laval University, Québec City, QC, Canada G1V 0A6.
authors.forename: Hendra
authors.initials: H
authors.lastname: Hermawan
authors.forename: Diego
authors.initials: D
authors.lastname: Mantovani
mesh_terms: D020341:Absorbable Implants; D019245:Compressive Strength / Q000187:drug effects; D003331:Coronary Vessels / Q000187:drug effects* / Q000502:physiology*; D006801:Humans; D007501:Iron / Q000494:pharmacology*; D008345:Manganese / Q000494:pharmacology*; D008422:Materials Testing / Q000379:methods*; D008855:Microscopy, Electron, Scanning; D013193:Stainless Steel / Q000494:pharmacology; D015607:Stents
chemical_list: C083456:ferro-manganese alloy; D013193:Stainless Steel; D008345:Manganese; D007501:Iron
keywords: Annealing; Biodegradable stent; Laser cutting; Metal; Stent fabrication