title: Subcutaneous fat necrosis after selective head cooling in an infant.
abstract: Hypoxic-ischemic encephalopathy in neonates causes irreversible damage to tissue and organs and results in multiple organ failure and poor outcome. Therapeutic hypothermia is the most effective therapy in neonates with hypoxic-ischemic encephalopathy. We report here a case of subcutaneous fat necrosis (SCFN) after therapeutic hypothermia by selective head cooling. Selective head cooling was provided for 72 h after birth. SCFN developed on the patient's cheeks and back at the age of 21 days. Thus, SCFN may be caused by selective head cooling, similarly to whole-body cooling.
authors.affiliation: Department of Neonatology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Kuboi
authors.forename: Takashi
authors.initials: T
authors.lastname: Kusaka
authors.forename: Kaoru
authors.initials: K
authors.lastname: Okazaki
authors.forename: Uiko
authors.initials: U
authors.lastname: Kaku
authors.forename: Ryota
authors.initials: R
authors.lastname: Kakinuma
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kondo
authors.forename: Akira
authors.initials: A
authors.lastname: Nishida
mesh_terms: D005218:Fat Necrosis / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006257:Head; D006801:Humans; D007036:Hypothermia, Induced / Q000009:adverse effects* / Q000379:methods; D020925:Hypoxia-Ischemia, Brain / Q000628:therapy*; D007231:Infant, Newborn; D050151:Subcutaneous Fat