title: [Calciphylaxis, renal failure and gout. A patient with hyperuricemia as a risk factor for death].
abstract: BACKGROUND
  gout is an inflammatory arthritis that frequently is associated with obesity, alcohol consumption, hypertension and hypertriglyceridemia. The calciphylaxis is characterized by metastatic calcification to small and medium vessels. Both are associated independently with high mortality. When hyperuricemia and the calciphylaxis are present, the death risk is 80 %.
  
  
  METHODS
  a 51 year old man presented with clinical history of alcoholism and systemic arterial hypertension, and he developed limb ulcers, edema and uremic syndrome. Three week later, the patient died as a consequence of sepsis from Staphylococcus aureus. We emphasize the diagnostic approach of calciphylaxis, metabolic syndrome and comorbidities, cardiovascular and renal failure risk factors.
  
  
  CONCLUSIONS
  the hyperuricemia is included in the metabolic syndrome, as the result of genetic and behavioral factors. It is recognized as a cardiovascular risk. For this reason we must consider it in the clinical practice guidelines for the prevention and treatment of diseases with high mortality.
authors.affiliation: Departamento de Medicina Interna, Hospital General de Zona 1, Instituto Mexicano del Seguro Social, San Luis Potosí, San Luis Potosí, México. marcomtzmtz@hotmail.com.
authors.forename: Marco Ulises
authors.initials: MU
authors.lastname: Martínez-Martínez
authors.forename: Susana
authors.initials: S
authors.lastname: Román-Acosta
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Alvarez-Reyes
authors.forename: Cuauhtémoc
authors.initials: C
authors.lastname: Oros-Ovalle
authors.forename: Carlos
authors.initials: C
authors.lastname: Abud-Mendoza
mesh_terms: D002115:Calciphylaxis / Q000150:complications*; D017809:Fatal Outcome; D006073:Gout / Q000150:complications*; D006801:Humans; D033461:Hyperuricemia / Q000150:complications*; D008297:Male; D008875:Middle Aged; D051437:Renal Insufficiency / Q000150:complications*; D012307:Risk Factors
keywords: calciphylaxis; gout; renal insufficiency