title: Precocious puberty as initial presentation in mediastinal tumour.
abstract: Numerous disorders can cause precocious puberty in children, and germ cell tumours (GCT) are one of the rare causes . We report two cases of mediastinal malignant GCTs who presented with precocious puberty. Both patients had bulky and advanced disease, were aggressively treated with neo-adjuvant chemotherapy and surgery, and are surviving and free of disease.
authors.affiliation: Division of Pediatric Oncology, Regional Cancer Centre, Trivandrum, Kerala, India. drmanjushanair@gmail.com
authors.forename: Manjusha
authors.initials: M
authors.lastname: Nair
authors.forename: P
authors.initials: P
authors.lastname: Kusumakumary
authors.forename: Anu
authors.initials: A
authors.lastname: Ninan
mesh_terms: D002648:Child; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis*; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis*; D011629:Puberty, Precocious / Q000175:diagnosis*