title: [Early intervention practice in Toyama Prefecture: efforts to improve the clinical service].
abstract: We report our activity in the Consultation and Support Service in Toyama (CAST), a clinical service provided by the collaboration of Toyama Prefectural Mental Health Center and University Hospital of Toyama(UHT). About 23% of users diagnosed with at-risk mental state (ARMS), during October 2006 until March 2012, transitioned to overt schizophrenia. More than half of the subjects who continued to visit the specialized clinic in UHT were treated with antipsychotic drugs. We encountered a case of schizophrenia in which early treatment with an atypical psychotic drug was effective in normalizing cognitive function and achieving a good social consequence. The ability of mismatch negativity, an event-related potential, to predict progression to psychosis in subjects with ARMS is discussed. Further efforts should be directed towards improving long-term outcomes, such as social function, for users of the CAST.
authors.affiliation: Department of Neuropsychiatry, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences.
authors.forename: Tomiki
authors.initials: T
authors.lastname: Sumiyoshi
authors.forename: Shimako
authors.initials: S
authors.lastname: Nishiyama
authors.forename: Yuko
authors.initials: Y
authors.lastname: Higuchi
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Takahashi
authors.forename: Tadasu
authors.initials: T
authors.lastname: Matsuoka
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Muranaka
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Kurachi
authors.forename: Yuko
authors.initials: Y
authors.lastname: Mizukami
authors.forename: Satoru
authors.initials: S
authors.lastname: Kazukawa
authors.forename: Michio
authors.initials: M
authors.lastname: Suzuki
mesh_terms: D003937:Diagnosis, Differential; D018479:Early Intervention, Educational / Q000379:methods; D006801:Humans; D007564:Japan; D011618:Psychotic Disorders / Q000175:diagnosis / Q000628:therapy*; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome