title: Successful switch to oral therapy with doxycycline in the case of an actinomycotic hepatic abscess.
abstract: A 72-year-old female was admitted with the symptoms of malaise, loss of appetite, upper right quadrant pain, fever, and sweats, which had been present for last 7 days. CT-scan of the abdomen revealed a hypodense mass in the right liver lobe; histopathological examination of the biopsy specimen yielded a diagnosis of actinomycotic abscess. Treatment with intravenous ampicillin for 8 weeks followed by a course of oral doxicycline for 28 weeks resulted in the complete resolution of the abscess.
authors.affiliation: Matei Bals Infectious Diseases Institute, Bucharest, Romania. dianapetrache07@yahoo.com
authors.forename: Diana
authors.initials: D
authors.lastname: Petrache
authors.forename: Gabriel-Adrian
authors.initials: GA
authors.lastname: Popescu
mesh_terms: D000196:Actinomycosis / Q000188:drug therapy* / Q000382:microbiology* / Q000473:pathology; D061605:Administration, Intravenous; D000284:Administration, Oral; D000368:Aged; D000667:Ampicillin / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001706:Biopsy; D004318:Doxycycline / Q000008:administration & dosage*; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008099:Liver / Q000473:pathology; D008100:Liver Abscess / Q000188:drug therapy* / Q000382:microbiology* / Q000473:pathology; D008853:Microscopy; D011860:Radiography, Abdominal; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000667:Ampicillin; D004318:Doxycycline