title: Aquagenic urticaria in twins.
abstract: We describe the case of 18 year old twin brothers who presented to our unit with a 3 year history of aquagenic urticaria. This rare form of urticaria usually presents within an hour of contact with water. The aetiology is unknown. Most cases are sporadic but there are a small number of familial cases in the medical literature. A specific genetic mutation has not yet been found. To our knowledge, this is the first report of aquagenic urticaria in monozygotic twins, further supporting a genetic component to this disease.
authors.affiliation: Cutaneous Allergy Department, St John's Institute of Dermatology, Guy's & St Thomas' NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London, UK. annekekai@doctors.org.uk.
authors.forename: Anneke C
authors.initials: AC
authors.lastname: Kai
authors.forename: Carsten
authors.initials: C
authors.lastname: Flohr