title: [Incidence of meningitis caused by Haemophilus influenzae in the state of Rio Grande do Sul 1999-2010: impact of vaccination campaign].
abstract: This article seeks to analyze and update the epidemiological situation of meningitis caused by Haemophilus influenzae type b in the past 10 years in the state of Rio Grande do Sul (RS). It is a retrospective, descriptive study, which used the data notification system of meningitis and vaccination campaign coverage, stored in the Epidemiological TABNET online database, for the period from 1999 to 2010. Cases notified and confirmed were used and the selection criteria were the year when the symptoms were detected, age, diagnosis, and evolution. Nineteen health centers in the state of Rio Grande do Sul were analyzed. The z-test was used to evaluate comparisons between the proportions. In the period studied, 3043 confirmed cases of bacterial meningitis were reported, of which 6.77% were caused by H. influenzae. The incidence and mortality rates of meningitis caused by H. influenzae, without taking age group into consideration, fell significantly (95.6%) after 1999. Children under one year old continue to be the most affected (52%), there being no change in lethality. The results presented revealed a positive impact of Hib vaccination strategies in the state of Rio Grande do Sul over the past ten years.
authors.affiliation: Departamento de Análises Clínicas e Toxicológicas, Centro de Ciências da Saúde, Universidade Federal de Santa Maria. Av. Roraima s/n. Prédio 26/CCS, Camobi. 97105-900 Santa Maria RS. joaogss_med@hotmail.com
authors.forename: João Guilherme Stadler
authors.initials: JG
authors.lastname: Schossler
authors.forename: Sandra Trevisan
authors.initials: ST
authors.lastname: Beck
authors.forename: Marli Matiko Anraku
authors.initials: MM
authors.lastname: de Campos
authors.forename: Lourdes Boufleur
authors.initials: LB
authors.lastname: Farinha
mesh_terms: D001938:Brazil / Q000453:epidemiology; D002675:Child, Preschool; D018073:Haemophilus Vaccines / Q000627:therapeutic use*; D019741:Haemophilus influenzae type b; D006801:Humans; D015994:Incidence; D007223:Infant; D008583:Meningitis, Haemophilus / Q000453:epidemiology* / Q000517:prevention & control*; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D018073:Haemophilus Vaccines