title: Two new furostanol saponins from Aspidistra typica.
abstract: Two new furostanol saponins (1 and 2), along with one known saponin (3), were obtained from the rhizomes of Aspidistra typica Baill. Their structures were elucidated as (25R)-26-O-β-d-glucopyranosyl-furost-5-ene-12-one-3β,22α,26-triol-3-O-β-d-glucopyranosyl-(1 → 2)-[β-d-xylopyranosyl-(1 → 3)]-β-d-glucopyranosyl-(1 → 4)-β-d-galactopyranoside (1, typaspidoside A), (25S)-26-O-β-d-glucopyranosyl-furost-5-ene-12-one-3β,22α,26-triol-3-O-β-d-glucopyranosyl-(1 → 2)-[β-d-xylopyranosyl-(1 → 3)]-β-d-glucopyranosyl-(1 → 4)-β-d-galactopyranoside (2, 25S-typaspidoside A), and timosaponin H1 (3), based on the integrative spectroscopic analysis of 1D- and 2D-NMR experiments, ESI-MS data and chemical evidence. The investigation on the chemical components of this plant is reported for the first time.
authors.affiliation: School of Pharmaceutical Sciences, Central South University, Changsha 410013, China.
authors.forename: Jiang-Ming
authors.initials: JM
authors.lastname: Cui
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Kang
authors.forename: He-Shui
authors.initials: HS
authors.lastname: Yu
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhao
authors.forename: Cheng-Qi
authors.initials: CQ
authors.lastname: Xiong
authors.forename: Chao
authors.initials: C
authors.lastname: Liu
authors.forename: Bai-Ping
authors.initials: BP
authors.lastname: Ma
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D004578:Electron Spin Resonance Spectroscopy; D019668:Liliaceae / Q000737:chemistry*; D015394:Molecular Structure; D027343:Rhizome / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D004365:Drugs, Chinese Herbal; D012503:Saponins; D013256:Steroids; C582534:typaspidoside A