title: Extrapulmonary disseminated tuberculosis with tuberculous adrenalitis: a stitch in time saves nine.
abstract: A 40-year-old manual labourer presented with easy fatiguability, recurrent vomiting and loss of weight of 3 months, duration. Upon examination, there was significant axillary and cervical lymphadenopathy. No pallor, icterus or clubbing was evident. There was generalised hyperpigmentation and multiple oral ulcers. The blood pressure 90/60 mm Hg in the right upper limb in the supine position. Investigations showed a low serum cortisol. Mantoux test was strongly positive (20 mm).A fine needle aspiration biopsy of the cervical lymph node revealed reactive changes. Bone marrow aspiration and biopsy were normal. Cervical lymph node biopsy showed caseating granulomas suggestive of tuberculous lymphadenitis. A CT scan of the abdomen showed bilaterally enlarged adrenal glands with hypodense areas suggestive of necrosis. He was diagnosed with extrapulmonary disseminated tuberculosis with tuberculous adrenalitis. He was started on directly observed therapy (DOTS) for disseminated tuberculosis and 40 mg of prednisolone. He is improving with treatment.
authors.affiliation: Department of Internal Medicine, Medical College Hospital, Thiruvananthapuram, Kerala, India. drcrajasekharan@yahoo.com
authors.forename: Chandrasekharan
authors.initials: C
authors.lastname: Rajasekharan
authors.forename: Sivasankarannair
authors.initials: S
authors.lastname: Ajithkumar
authors.forename: Varghese
authors.initials: V
authors.lastname: Anto
authors.forename: Rajasekharan
authors.initials: R
authors.lastname: Parvathy
mesh_terms: D000224:Addison Disease / Q000209:etiology*; D000307:Adrenal Gland Diseases / Q000150:complications / Q000175:diagnosis*; D000328:Adult; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D014376:Tuberculosis / Q000175:diagnosis; D014383:Tuberculosis, Endocrine / Q000150:complications / Q000175:diagnosis*