title: [Effect of OHOLV on the remineralization of early enamel caries].
abstract: OBJECTIVE
  To observe the effect of OHOLV on the remineralization of early enamel caries.
  
  
  METHODS
  Fifty bovine teeth with artificial early caries were divided into five groups randomly and treated with OHOLV, casein phosphopeptide amorphous calcium phosphate (CPP-ACP), NaF, OHOLV+NaF and distilled and deionized water (DDW) respectively. Then the teeth were subjected to the pH-cycling. The surface microhardness (SMH) of enamel before demineralization and after remineralization were measured by microhardness detector and the histomorphologic changes of the enamel surface were compared by scanning election microscope (SEM).
  
  
  RESULTS
  The SMH of all the experimental groups increased significantly after remineralization (P < 0.001). The SMH of the OHOLV group was lower than that of NaF group (P < 0.001), while there was no significant difference between the OHOLV group and the CPP-ACP group (P > 0.05). After remineralization, a large amount of comparatively large mineral particles deposited on the surface of the enamel treated with OHOLV.
  
  
  CONCLUSIONS
  OHOLV can promote the remineralization of the early enamel caries.
authors.affiliation: State Key Laboratory of Oral Diseases, Dept. of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Sui
authors.forename: Yuan
authors.initials: Y
authors.lastname: Liu
authors.forename: Ran
authors.initials: R
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: Zou
mesh_terms: D000818:Animals; D002130:Calcium Phosphates; D002327:Cariostatic Agents; D002364:Caseins; D002417:Cattle; D003731:Dental Caries; D003743:Dental Enamel; D014089:Tooth Remineralization
chemical_list: D002130:Calcium Phosphates; D002327:Cariostatic Agents; D002364:Caseins; C519480:amorphous calcium phosphate