title: Calcification of a hydrophilic acrylic intraocular lens: case report with laboratory analysis.
abstract: We analyzed a single-piece plate-type hydrophilic acrylic posterior chamber intraocular lens (IOL) that was explanted due to a progressive loss of vision, which occurred 6 years after uncomplicated phacoemulsification. Gross and light microscopy, as well as anterior segment optical coherence tomography (OCT) revealed granular deposits below the IOL surface. Light scattering, as measured with Scheimpflug photography and densitometry analyses was found to be increased; spectrophotometry demonstrated a decrease in the light transmittance of the explanted lens. The granular deposits within the IOL material were found to be composed of calcium by histochemical methods (alizarin red and Von Kossa stains). To our knowledge this is the only report of calcification of this IOL design.
authors.affiliation: John A.-Moran Eye Center, University of Utah, 65, Mario-Capecchi Drive, Salt Lake City, 84132 Utah, USA.
authors.forename: Z M
authors.initials: ZM
authors.lastname: Bodnar
authors.forename: P
authors.initials: P
authors.lastname: Rozot
authors.forename: L
authors.initials: L
authors.lastname: Leishman
authors.forename: A
authors.initials: A
authors.lastname: Ollerton
authors.forename: J
authors.initials: J
authors.lastname: Michelson
authors.forename: S
authors.initials: S
authors.lastname: Plasse-Fauque
authors.forename: L
authors.initials: L
authors.lastname: Werner
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D002114:Calcinosis / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D019411:Clinical Laboratory Techniques; D020878:Device Removal; D005260:Female; D006801:Humans; D007905:Lens Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D019654:Lens Implantation, Intraocular / Q000009:adverse effects; D007910:Lenses, Intraocular; D018918:Phacoemulsification; D011475:Prosthesis Failure / Q000009:adverse effects*
chemical_list: D000180:Acrylic Resins
keywords: Acrylique hydrophile; Anterior segment optical coherence tomography; Calcification; Explantation; Hydrophilic acrylic; Implant intraoculaire; Intraocular lens; Tomographie à cohérence optique du segment antérieur