title: Quantitative validation of left atrial structure and function by two-dimensional and three-dimensional speckle tracking echocardiography: a comparative study with three-dimensional computed tomography.
abstract: BACKGROUND
  The aim of this study was to validate the accuracy of three-dimensional (3D) speckle tracking echocardiography (STE) and two-dimensional (2D)-STE for the assessment of left atrial (LA) volume and function by comparison with 3D-computed tomography (CT) performed on the same day as STE.
  
  
  METHODS
  LA phasic volume and emptying function (EF) were measured in 28 patients with paroxysmal atrial fibrillation undergoing catheter ablation (62±11 years old) using both 3D-STE and 2D-STE during sinus rhythm. LA phasic volume and function measured by 3D-STE and 2D-STE were validated using 3D-CT as a gold standard.
  
  
  RESULTS
  The intraobserver correlation coefficient and variability in maximum LA volume assessed by 3D-STE were 0.99 and 1.4±6.0%, respectively. The interobserver correlation coefficient and variability in maximum LA volume assessed by 3D-STE were 0.99 and 0.2±4.5%, respectively. There were strong correlations between LA phasic volume measured by 3D-CT and those measured by 3D-STE (r=0.98, p<0.001). There were correlations between LA phasic function measured by 3D-CT and those measured by 3D-STE (r=0.85-0.88, p<0.001). There was a better agreement between 3D-CT and 3D-STE in the assessment of LA phasic volumes and function than between 3D-CT and 2D-STE in apical 2- and 4-chamber view.
  
  
  CONCLUSIONS
  3D-STE allows more accurate measurement of LA volume and function than 2D-STE and has high reproducibility.
authors.affiliation: Department of Cardiology, Gifu Prefectural General Medical Center, Gifu, Japan.
authors.forename: Maki
authors.initials: M
authors.lastname: Nagaya
authors.forename: Masanori
authors.initials: M
authors.lastname: Kawasaki
authors.forename: Ryuhei
authors.initials: R
authors.lastname: Tanaka
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Onishi
authors.forename: Noriaki
authors.initials: N
authors.lastname: Sato
authors.forename: Koji
authors.initials: K
authors.lastname: Ono
authors.forename: Takatomo
authors.initials: T
authors.lastname: Watanabe
authors.forename: Shingo
authors.initials: S
authors.lastname: Minatoguchi
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Miwa
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Goto
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hirose
authors.forename: Masazumi
authors.initials: M
authors.lastname: Arai
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Noda
authors.forename: Sachiro
authors.initials: S
authors.lastname: Watanabe
authors.forename: Shinya
authors.initials: S
authors.lastname: Minatoguchi
mesh_terms: D000368:Aged; D016279:Atrial Function, Left; D002306:Cardiac Volume; D004452:Echocardiography / Q000379:methods*; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006325:Heart Atria; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: Atrial function; Atrial volume; Speckle tracking; Three-dimensional echocardiography