title: Influence of axial length on conjunctivochalasis.
abstract: OBJECTIVE
  To investigate the relation between the severity of conjunctivochalasis and the axial length (AL) of the eyeball.
  
  
  METHODS
  A prospective nonrandomized study was performed on 165 patients aged 51 to 88 years. The age, gender, medical history, ocular history, grade and other parameters of inferior conjunctivochalasis (classified as nasal, middle, and temporal), and AL were determined in all patients. Patients were divided into a short AL group (≤ 22.0 mm), a medium AL group (>22.0 to ≤ 24.0 mm), and a long AL group (>24.0 mm).
  
  
  RESULTS
  The short AL group tended to have higher grades of temporal and nasal conjunctivochalasis compared with the medium and long AL groups. Multivariate logistic regression analysis showed that the total conjunctivochalasis score (the sum of the scores for the temporal, middle, and nasal regions) was significantly associated with the age [odds ratio (OR) = 1.32, P = 0.001] and the AL (OR = 0.81, P = 0.029). In addition, the AL was independently associated with the grade of conjunctivochalasis after adjustment for age (OR = 0.80, P = 0.020).
  
  
  CONCLUSIONS
  This was the first assessment of the relationship between the AL and the grade of conjunctivochalasis. Our findings suggest that the severity of conjunctivochalasis is dependent on the AL, with a short AL contributing to the pathogenesis of conjunctivochalasis.
authors.affiliation: Department of Ophthalmology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan. mimurat-tky@umin.ac.jp
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Mimura
authors.forename: Satoru
authors.initials: S
authors.lastname: Yamagami
authors.forename: Yuko
authors.initials: Y
authors.lastname: Kamei
authors.forename: Mari
authors.initials: M
authors.lastname: Goto
authors.forename: Masao
authors.initials: M
authors.lastname: Matsubara
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D058452:Axial Length, Eye / Q000473:pathology*; D003229:Conjunctival Diseases / Q000473:pathology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index