title: Effects of an acute bout of resistance exercise on fiber-type specific to GLUT4 and IGF-1R expression.
abstract: The effects of resistance exercise on fiber-type-specific expression of insulin-like growth factor I receptor (IGF-1R) and glucose transporter 4 (GLUT4) was determined in 6 healthy males. The expression of both genes increased in Type I fibers (p < 0.05), but only GLUT4 increased (p < 0.05) in Type II fibers. These data demonstrates that an acute bout of resistance exercise can up-regulate mechanisms of glucose uptake in slow and fast-twitch fibers, but the IGF signaling axis may not be as effective in fast-twitch fibers.
authors.affiliation: a Department of Health, Sport, and Exercise Sciences, University of Kansas, Lawrence, KS 66045, USA.
authors.forename: Philip M
authors.initials: PM
authors.lastname: Gallagher
authors.forename: Chad D
authors.initials: CD
authors.lastname: Touchberry
authors.forename: Kelli
authors.initials: K
authors.lastname: Teson
authors.forename: Everlee
authors.initials: E
authors.lastname: McCabe
authors.forename: Michelle
authors.initials: M
authors.lastname: Tehel
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Wacker
mesh_terms: D004043:Dietary Fiber; D015444:Exercise; D051275:Glucose Transporter Type 4; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D018656:Muscle Fibers, Fast-Twitch / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D004043:Dietary Fiber; D051275:Glucose Transporter Type 4; D007334:Insulin-Like Growth Factor I