title: In vivo Anticancer Activities of Benzophenone Semicarbazone against Ehrlich Ascites Carcinoma Cells in Swiss Albino Mice.
abstract: OBJECTIVE
  Benzophenone semicarbazone (BSC) was synthesized and characterized to identify compounds with anticancer activities.
  
  
  METHODS
  Anticancer activities were studied against Ehrlich Ascites Carcinoma (EAC) cells in Swiss albino mice by monitoring parameters such as tumor weight measurement, survival time of tumor bearing mice, tumor cell growth inhibition, and so on. Some hematological parameters, such as red blood cells, white blood cells, and hemoglobin content, were also measured.
  
  
  RESULTS
  The results showed that BSC has a positive effect against EAC cells. An assessment was conducted by comparing these results with those obtained using the standard drug bleomycin.
  
  
  CONCLUSIONS
  The BSC compound can be considered as a potent anticancer agent.
authors.affiliation: Department of Applied Chemistry and Chemical Engineering, University of Rajshahi, Rajshahi 6205, Bangladesh.
authors.forename: Khairul
authors.initials: K
authors.lastname: Islam
authors.forename: Shaikh M Mohsin
authors.initials: SM
authors.lastname: Ali
authors.forename: Mele
authors.initials: M
authors.lastname: Jesmin
authors.forename: Jahan Ara
authors.initials: JA
authors.lastname: Khanam
keywords: EAC cell; anticancer activities; benzophenone semicarbazone