title: Bilateral toe necrosis resulting from norepinephrine bitartrate usage.
abstract: Acute limb ischemia may manifest by ischemic rest pain, ischemic ulcers, or gangrene. Acute arterial occlusion can be the result of emboli from a distant source, acute thrombosis of a previously patent artery, or direct trauma to an artery. Toe necrosis resulting from norepinephrine bitartrate (Levophed; Hospira Inc, Lake Forest, Illinois) is a rare case.
authors.affiliation: Wright State University Boonshoft School of Medicine, Dayton, OH, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Simman
authors.forename: Laemthong
authors.initials: L
authors.lastname: Phavixay
mesh_terms: D000671:Amputation, Surgical; D005260:Female; D006801:Humans; D007511:Ischemia / Q000139:chemically induced* / Q000601:surgery; D008875:Middle Aged; D009336:Necrosis; D009638:Norepinephrine / Q000009:adverse effects*; D014034:Toes / Q000098:blood supply* / Q000601:surgery; D014662:Vasoconstrictor Agents / Q000009:adverse effects*
chemical_list: D014662:Vasoconstrictor Agents; D009638:Norepinephrine