title: Laryngeal sarcoidosis: a case report presenting transglottic involvement.
abstract: Isolated laryngeal sarcoidosis is a very rare disease. In most cases, it will present as a supraglottic pale edematous swelling. In our case, the patient presented with hoarseness and dyspnea during exertion. Laryngeal examination did show not only supraglottic edema but also prominent subglottic swelling and edematous true vocal folds. Histology showed noncaseating granulomas. After excluding other causes and localizations, the patient was diagnosed with laryngeal sarcoidosis and treated with systemic corticosteroid with good result. We describe our case of isolated transglottic sarcoidosis and discuss the disease, its presentation, diagnosis, and therapeutic options.
authors.affiliation: Department of Otorhinolaryngology/Head and Neck Surgery, Leiden University Medical Centre, Leiden, The Netherlands. E.M.J.M.van_den_Broek@lumc.nl
authors.forename: Emke M J M
authors.initials: EM
authors.lastname: van den Broek
authors.forename: Bas J
authors.initials: BJ
authors.lastname: Heijnen
authors.forename: Berit M
authors.initials: BM
authors.lastname: Verbist
authors.forename: Elisabeth V
authors.initials: EV
authors.lastname: Sjögren
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007818:Laryngeal Diseases / Q000175:diagnosis / Q000473:pathology*; D007830:Larynx / Q000473:pathology*; D012507:Sarcoidosis / Q000175:diagnosis / Q000473:pathology*
keywords: Larynx; Sarcoidosis