title: Ketogenic diets and pain.
abstract: Ketogenic diets are well established as a successful anticonvulsant therapy. Based on overlap between mechanisms postulated to underlie pain and inflammation, and mechanisms postulated to underlie therapeutic effects of ketogenic diets, recent studies have explored the ability for ketogenic diets to reduce pain. Here we review clinical and basic research thus far exploring the impact of a ketogenic diet on thermal pain, inflammation, and neuropathic pain.
authors.affiliation: Neuroscience Program and Department of Psychology, Trinity College, Hartford, CT 06106, USA. susan.masino@trincoll.edu
authors.forename: Susan A
authors.initials: SA
authors.lastname: Masino
authors.forename: David N
authors.initials: DN
authors.lastname: Ruskin
mesh_terms: D000818:Animals; D055423:Diet, Ketogenic / Q000379:methods*; D006801:Humans; D007249:Inflammation / Q000178:diet therapy / Q000378:metabolism; D007659:Ketones / Q000378:metabolism; D010146:Pain / Q000150:complications / Q000178:diet therapy* / Q000209:etiology; D017288:Pain Threshold / Q000502:physiology; D010812:Physical Stimulation; D051381:Rats
chemical_list: D007659:Ketones
keywords: Taxol; chronic constriction injury; glucose; hypoalgesia; inflammation; ketones; metabolismc; neuropathic pain