title: What is the impact of electromagnetic waves on epileptic seizures?
abstract: BACKGROUND
  The effects of electromagnetic waves (EMWs) on humans and their relationship with various disorders have been investigated. We aimed to investigate the effects of exposure to different frequencies of EMWs in various durations in a mouse epilepsy model induced by pentylenetetrazole (PTZ).
  
  
  METHODS
  A total of 180 4-week-old male mice weighing 25-30 g were used in this study. Each experimental group consisted of 10 mice. They were exposed to 900, 700, 500, 300, and 100 MHz EMWs for 20 hours, 12 hours and 2 hours. Following electromagnetic radiation exposure, 60 mg/kg of PTZ was injected intraperitoneally to all mice. Each control was also injected with PTZ without any exposure to EMW. The latency of initial seizure and most severe seizure onset were compared with controls.
  
  
  RESULTS
  The shortest initial seizure latency was noted in the 12-hour group, followed by the 700 MHz. The mean initial seizure latencies in the 2-hour EMW exposed group was significantly shorter compared to that in the 12- and 20-hour groups. There was no significant difference between 12- and 20-hour EMW exposed groups. There was a significant difference between control and 2- and 10-hour EMW exposed groups. No statistically significant differences were noted in mean latencies of the most severe seizure latency, following 20-, 12-, and 2- hour EMW exposed groups and control groups.
  
  
  CONCLUSIONS
  Our findings suggest that acute exposure to EMW may facilitate epileptic seizures, which may be independent of EMW exposure time. This information might be important for patients with epilepsy. Further studies are needed.
authors.affiliation: Department of Neurology, Faculty of Medicine, Maltepe University, Istanbul, Turkey. cinarnilgun@gmail.com
authors.forename: Nilgun
authors.initials: N
authors.lastname: Cinar
authors.forename: Sevki
authors.initials: S
authors.lastname: Sahin
authors.forename: Oguz O
authors.initials: OO
authors.lastname: Erdinc
mesh_terms: D000818:Animals; D060733:Electromagnetic Radiation; D004827:Epilepsy / Q000473:pathology* / Q000503:physiopathology; D007837:Latency Period, Psychological; D008297:Male; D051379:Mice