title: Tumour thrombosis and patterns of fluorine-18 fluorodeoxyglucose uptake: a pictorial review.
abstract: Tumour thrombosis (TT) is a very rare but serious complication in oncologic patients. The presence of TT has a significant impact on tumour staging, treatment decisions and prognosis in many malignancies. Current diagnostic techniques show poor ability to differentiate between bland and malignant thrombi; tumour thrombi are also usually inaccessible for biopsies, making their diagnosis difficult. In recent times, fluorine-18 fluorodeoxyglucose PET/computed tomography (F-FDG PET/CT) has well established its role in oncological imaging because of the high metabolic contrast of F-FDG between malignant and normal tissue. Patients with tumour thrombi may benefit from F-FDG PET/CT imaging when TT cannot be diagnosed precisely by other conventional imaging modalities. Here we provide a pictorial review of a few common and unusual sites of tumour thrombus in different malignancies and their patterns of F-FDG uptake.
authors.affiliation: Department of Nuclear Medicine & PET/CT, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India. hrushi.auri@hotmail.com
authors.forename: Hrushikesh U
authors.initials: HU
authors.lastname: Aurangabadkar
authors.forename: Lalitha
authors.initials: L
authors.lastname: Palle
authors.forename: Zakir
authors.initials: Z
authors.lastname: Ali
mesh_terms: D001692:Biological Transport; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism* / Q000493:pharmacokinetics; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D013927:Thrombosis / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism* / Q000503:physiopathology
chemical_list: D019788:Fluorodeoxyglucose F18