title: High-resolution multimodal imaging of multiple evanescent white dot syndrome.
abstract: The integrity of macular morphology was examined in a patient with multiple evanescent white dot syndrome (MEWDS) diagnosed through clinical and investigational adaptive optics (AO) retinal imaging techniques. Imaging was performed during the acute and recovery phases to examine changes in retinal morphology, revealing characteristic small multifocal white dots in the perifoveal region and a granular appearance in the fovea. Fluorescein angiography revealed early and intermediate hyperfluorescence, and regions of decreased fundus autofluorescence were observed. Photoreceptor disruption was apparent during the acute phase and recurrence. Conventional multimodal imaging combined with AO imaging offers more insight into the pathology of MEWDS by providing complementary views of the retina throughout the acute phase, recovery, and recurrence.
authors.affiliation: Center for Biomedical Engineering, University of Texas Medical Branch, Galveston, Texas, USA.
authors.forename: Adam
authors.initials: A
authors.lastname: Boretsky
authors.forename: Sarah
authors.initials: S
authors.lastname: Mirza
authors.forename: Faraz
authors.initials: F
authors.lastname: Khan
authors.forename: Massoud
authors.initials: M
authors.lastname: Motamedi
authors.forename: Frederik J G M
authors.initials: FJ
authors.lastname: van Kuijk
mesh_terms: D000328:Adult; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007834:Lasers; D064847:Multimodal Imaging / Q000379:methods*; D009887:Ophthalmoscopy / Q000379:methods*; D012164:Retinal Diseases / Q000175:diagnosis*