title: [Brachytherapy role in pediatric rhabdomyosarcomas].
abstract: Brachytherapy in paediatric malignancies is rarely used, limited to expert institutions. The most frequent tumour sites treated with brachytherapy are gynaecological rhabdomyosarcomas, and prostate/bladder rhabdomyosarcomas. Ballistic advantages make brachytherapy technique the treatment of choice, with a high and selective protection of organs at risk. Techniques, brachytherapy modalities (low dose-rate, high dose-rate, pulsed dose-rate), doses and indications vary according to centres. Brachytherapy advantages are in relation with ballistic properties, allowing a very high dose to the target with normal tissue sparing. This review analyzes brachytherapy techniques, indications and results according to the two most frequent tumour sites: gynaecological and bladder/prostate tumours. This technique requires a muldisciplinary approach.
authors.affiliation: Service de curiethérapie, institut de cancérologie Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif, France. christine.haie@igr.fr
authors.forename: C
authors.initials: C
authors.lastname: Haie-Meder
authors.forename: R
authors.initials: R
authors.lastname: Mazeron
authors.forename: H
authors.initials: H
authors.lastname: Martelli
authors.forename: O
authors.initials: O
authors.lastname: Oberlin
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D002648:Child; D002986:Clinical Trials as Topic; D005260:Female; D005833:Genital Neoplasms, Female / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008297:Male; D058958:Organs at Risk; D010348:Patient Care Team; D010412:Penile Neoplasms / Q000532:radiotherapy / Q000601:surgery; D011874:Radiometry; D011879:Radiotherapy Dosage; D012208:Rhabdomyosarcoma / Q000532:radiotherapy* / Q000601:surgery; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000532:radiotherapy / Q000601:surgery