title: Worms--a "license to kill".
abstract: Worm infections can cause severe harm and death to both humans and numerous domestic and wild animals. Despite the fact that there are many beneficial worm species, veterinarians, physicians and parasitologists have multiple reasons to combat parasitic worms. The pros and cons of various approaches for the discovery of new control methods are discussed, including novel anthelmintics, vaccines and genetic approaches to identify novel drug and vaccine targets. Currently, the mainstay of worm control remains chemotherapy and prophylaxis. The importance of knowledgeable and wise use of the available anthelmintics is highlighted.
authors.affiliation: Novartis Centre de Recherche Santé Animale, CH-1566 St-Aubin, Switzerland. ronald.kaminsky@novartis.com
authors.forename: Ronald
authors.initials: R
authors.lastname: Kaminsky
authors.forename: Lucien
authors.initials: L
authors.lastname: Rufener
authors.forename: Jacques
authors.initials: J
authors.lastname: Bouvier
authors.forename: Regina
authors.initials: R
authors.lastname: Lizundia
authors.forename: Sandra
authors.initials: S
authors.lastname: Schorderet Weber
authors.forename: Heinz
authors.initials: H
authors.lastname: Sager
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D004351:Drug Resistance; D006373:Helminthiasis / Q000188:drug therapy / Q000517:prevention & control*; D006376:Helminths / Q000187:drug effects* / Q000235:genetics / Q000276:immunology; D006801:Humans; D014612:Vaccines
chemical_list: D000871:Anthelmintics; D014612:Vaccines
keywords: Drug resistance; Nematodes; Parasitic worms