title: Brotherhood brings orphans in from the cold.
abstract: Detection and classification of related proteins significantly aids in prioritizing structural determination targets. In this issue of Structure, Rubinstein and colleagues describe an improved method for categorizing members of variable protein families and demonstrate its utility for the immunoglobulin superfamily.
authors.affiliation: Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98103, USA. ccarrico@gmail.com
authors.forename: Chris
authors.initials: C
authors.lastname: Carrico