title: Epidermolysis bullosa pruriginosa triggered by scabies infestation.
abstract: Epidermolysis bullosa pruriginosa (EB-Pr) is an unusual variant of dystrophic EB. Potential genetic disease modifiers and metabolic factors have been investigated, but thus far no specific insight into this phenotype has emerged. We report an in-depth description of three patients diagnosed as having EB-Pr in whom this particular phenotype developed after scabies infestation and dramatically improved after full treatment. This short communication suggests that scabies infestation could be one of the important triggering factors for the development of the EB-Pr phenotype.
authors.affiliation: Department of Dermatology, St George Hospital, Sydney, New South Wales, Australia.
authors.forename: Jaehwan
authors.initials: J
authors.lastname: Kim
authors.forename: Chee Hoou
authors.initials: CH
authors.lastname: Loh
authors.forename: Dedee F
authors.initials: DF
authors.lastname: Murrell
mesh_terms: D000818:Animals; D004820:Epidermolysis Bullosa / Q000209:etiology*; D016108:Epidermolysis Bullosa Dystrophica; D006801:Humans; D008297:Male; D010641:Phenotype; D012532:Scabies / Q000150:complications*; D055815:Young Adult
keywords: COL7A1; collagen 7; dystrophic epidermolysis bullosa; epidermolysis bullosa pruriginosa; pruritus; scabies