title: Vertical osteoconductive characteristics of titanium implants with calcium-phosphate-coated surfaces - a pilot study in rabbits.
abstract: BACKGROUND
  Osteoconductive characteristics of different implant surface coatings are in the focus of current interest. The aim of the present study was to compare the vertical osteoconductivity at the implant shoulder of supracrestal inserted calcium-phosphate coated implants (SLA-CaP) with conventional sand-blasted/acid-etched (SLA) implants in a rabbit model.
  
  
  METHODS
  SLA-CaP and SLA implants were inserted bilaterally in the mandible of four rabbits in a split-mouth design. The implants were placed 2 mm supracrestal. After 3 weeks, at the left and right implant shoulder, the percentage of linear bone fill (PLF) as well as bone-implant contact (BIC-D) were determined.
  
  
  RESULTS
  After 3 weeks, newly formed woven bone could be found at the shoulder of the most of both surface-treated implants (75%). PLF was significantly higher in SLA-CaP implants (11.2% vs. 46.5%; n = 8, p = .008). BIC-D was significantly increased in the SLA-CaP implants (13.0% vs. 71.4%; n = 8, p < .001) as well.
  
  
  CONCLUSIONS
  The results of this study show for the first time that calcium-phosphate coated surfaces on supracrestal inserted implants have vertical osteoconductive characteristics and increase the bone-implant contact at the implant shoulder significantly in a rabbit model. In clinical long-term settings, these implants may contribute to a better vertical bone height.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany; State Medical and Pharmaceutical University "Nicolae Testemitanu", Chisinau, Moldova, Clinic for Oral & Maxillofacial Surgery, Chisinau, Moldova; State Medical and Pharmaceutical University "Nicolae Testemitanu," Chisinau, Moldova, Clinic for Oral & Maxillofacial Surgery, Chisinau, Moldova; Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany; Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
authors.forename: Eik
authors.initials: E
authors.lastname: Schiegnitz
authors.forename: Victor
authors.initials: V
authors.lastname: Palarie
authors.forename: Viorel
authors.initials: V
authors.lastname: Nacu
authors.forename: Bilal
authors.initials: B
authors.lastname: Al-Nawas
authors.forename: Peer Wolfgang
authors.initials: PW
authors.lastname: Kämmerer
mesh_terms: D000134:Acid Etching, Dental; D000818:Animals; D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D010865:Pilot Projects; D011817:Rabbits; D013499:Surface Properties; D014025:Titanium
chemical_list: D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; C020243:calcium phosphate; D014025:Titanium
keywords: animal study; calcium-phosphate; implant; osteoconductive characteristics