title: Diagnostic approaches for Rift Valley fever.
abstract: Disease outbreaks caused by arthropod-borne animal viruses (arboviruses) resulting in significant livestock and economic losses world-wide appear to be increasing. Rift Valley fever (RVF) virus is an important arbovirus that causes lethal disease in cattle, camels, sheep and goats in Sub-Saharan Africa. There is concern that this virus could spread because of global warming, increased animal trade or through bioterrorism. This paper discusses the current and developing approaches to diagnosis of RVF. Diagnostic assays are available for RVF, but availability can be limited and there is a need for global harmonization. Continued improvement of standard serological and viral genome amplification approaches, including new embedded/syndromic testing, biosensor, emerging virus detection and characterization technologies is needed.
authors.affiliation: Arthropod-Borne Animal Diseases Research Unit (ABADRU), Agricultural Research Service (ARS), US Department of Agriculture, Manhattan, KS, USA.
authors.forename: W C
authors.initials: WC
authors.lastname: Wilson
authors.forename: H M
authors.initials: HM
authors.lastname: Weingartl
authors.forename: B S
authors.initials: BS
authors.lastname: Drolet
authors.forename: K
authors.initials: K
authors.lastname: Davé
authors.forename: M H
authors.initials: MH
authors.lastname: Harpster
authors.forename: P A
authors.initials: PA
authors.lastname: Johnson
authors.forename: B
authors.initials: B
authors.lastname: Faburay
authors.forename: M G
authors.initials: MG
authors.lastname: Ruder
authors.forename: J A
authors.initials: JA
authors.lastname: Richt
authors.forename: D S
authors.initials: DS
authors.lastname: McVey
mesh_terms: D017954:Africa South of the Sahara; D000818:Animals; D015374:Biosensing Techniques / Q000662:veterinary; D004196:Disease Outbreaks / Q000517:prevention & control / Q000662:veterinary; D016679:Genome, Viral; D023281:Genomics; D014943:Global Health; D021141:Nucleic Acid Amplification Techniques; D012295:Rift Valley Fever / Q000175:diagnosis / Q000662:veterinary*; D012418:Ruminants; D012698:Serologic Tests / Q000662:veterinary*