title: Retroelements: molecular features and implications for disease.
abstract: Eukaryotic genomes comprise numerous retroelements that have a major impact on the structure and regulation of gene function. Retroelements are regulated by epigenetic controls, and they generate multiple miRNAs that are involved in the induction and progression of genomic instability. Elucidation of the biological roles of retroelements deserves continuous investigation to better understand their evolutionary features and implications for disease.
authors.affiliation: Department of Biological Sciences, College of Natural Sciences, Pusan National University, Busan 609-735, Republic of Korea.
authors.forename: Yi-Deun
authors.initials: YD
authors.lastname: Jung
authors.forename: Kung
authors.initials: K
authors.lastname: Ahn
authors.forename: Yun-Ji
authors.initials: YJ
authors.lastname: Kim
authors.forename: Jin-Han
authors.initials: JH
authors.lastname: Bae
authors.forename: Ja-Rang
authors.initials: JR
authors.lastname: Lee
authors.forename: Heui-Soo
authors.initials: HS
authors.lastname: Kim
mesh_terms: D000818:Animals; D004194:Disease / Q000235:genetics*; D019143:Evolution, Molecular; D016678:Genome; D042822:Genomic Instability; D006801:Humans; D035683:MicroRNAs / Q000235:genetics; D018626:Retroelements / Q000235:genetics*
chemical_list: D035683:MicroRNAs; D018626:Retroelements