title: Accessory breast cancer occurring concurrently with bilateral primary invasive breast carcinomas: a report of two cases and literature review.
abstract: The development of accessory breast tissue, which is found anywhere along the milk line, is attributed to the failure of milk line remnants to regress during embryogenesis. Primary tumors may arise from any ectopic breast tissue. Accessory breast cancer occurring concurrently with primary invasive breast cancer is extremely rare. Two such cases were reported in this article. One was a 43-year-old Chinese female who exhibited bilateral breast cancer (invasive ductal carcinoma, not otherwise specified, IDC-NOS) and an accessory breast carcinoma (IDC-NOS) incidentally identified in her left axilla. The ectopic breast tissue in her right axilla presented with adenosis. The patient was surgically treated, followed by postoperative docetaxel epirubicin (TE) chemotherapy. The second case was a 53-year-old Chinese female with bilateral breast cancer (apocrine carcinoma) accompanied by an accessory breast carcinoma (IDC-NOS) in her right axilla that was also incidentally identified. The patient was surgically treated after three doses of cyclophosphamide epirubicin docetaxel (CET) neoadjuvant chemotherapy, followed by adjuvant chemotherapy of the same regimen.
authors.affiliation: Department of Breast Cancer Pathology and Research Laboratory, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education, Tianjin 300060, China.
authors.forename: Jin-Yan
authors.initials: JY
authors.lastname: Hao
authors.forename: Cui-Cui
authors.initials: CC
authors.lastname: Yang
authors.forename: Fang-Fang
authors.initials: FF
authors.lastname: Liu
authors.forename: Yi-Ling
authors.initials: YL
authors.lastname: Yang
authors.forename: Shuai
authors.initials: S
authors.lastname: Li
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Li
authors.forename: Ya-Qing
authors.initials: YQ
authors.lastname: Li
authors.forename: Rong-Gang
authors.initials: RG
authors.lastname: Lang
authors.forename: Yu
authors.initials: Y
authors.lastname: Fan
authors.forename: Estifanos
authors.initials: E
authors.lastname: Paulos
authors.forename: Xin-Min
authors.initials: XM
authors.lastname: Zhang
authors.forename: Li
authors.initials: L
authors.lastname: Fu
keywords: accessory breast cancer; bilateral; invasive breast cancer; occurring concurrently; primary