title: Degradation of the plant defence hormone salicylic acid by the biotrophic fungus Ustilago maydis.
abstract: Salicylic acid (SA) is a key plant defence hormone which plays an important role in local and systemic defence responses against biotrophic pathogens like the smut fungus Ustilago maydis. Here we identified Shy1, a cytoplasmic U. maydis salicylate hydroxylase which has orthologues in the closely related smuts Ustilago hordei and Sporisorium reilianum. shy1 is transcriptionally induced during the biotrophic stages of development but not required for virulence during seedling infection. Shy1 activity is needed for growth on plates with SA as a sole carbon source. The trigger for shy1 transcriptional induction is SA, suggesting the possibility of a SA sensing mechanism in this fungus.
authors.affiliation: Max Planck Institute for Terrestrial Microbiology, Karl-von-Frisch-Strasse 10, D-35043, Marburg, Germany.
authors.forename: Franziska
authors.initials: F
authors.lastname: Rabe
authors.forename: Ziba
authors.initials: Z
authors.lastname: Ajami-Rashidi
authors.forename: Gunther
authors.initials: G
authors.lastname: Doehlemann
authors.forename: Regine
authors.initials: R
authors.lastname: Kahmann
authors.forename: Armin
authors.initials: A
authors.lastname: Djamei
mesh_terms: D001711:Biotransformation; D020869:Gene Expression Profiling; D015966:Gene Expression Regulation, Fungal; D006899:Mixed Function Oxygenases; D010935:Plant Diseases / Q000382:microbiology; D010937:Plant Growth Regulators / Q000378:metabolism*; D010944:Plants / Q000276:immunology* / Q000382:microbiology; D020156:Salicylic Acid / Q000378:metabolism*; D014588:Ustilago / Q000201:enzymology* / Q000378:metabolism*
chemical_list: D010937:Plant Growth Regulators; D006899:Mixed Function Oxygenases; C022619:salicylate 1-monooxygenase; D020156:Salicylic Acid