title: The relationships between renal compensatory hypertrophy etiologic factors and anthropometric development in the pediatric age group.
abstract: OBJECTIVE
  To evaluate the factors associated with compensatory hypertrophy in the functional kidneys of children.
  
  
  METHODS
  The medical files of patients with a solitary functional kidney were reviewed retrospectively. Data regarding anthropometric measurements, functional renal length, functional renal length of standard deviation score (SDS) of functional kidney at diagnosis, and end of follow-up were obtained. Patients were divided into 2 groups, those with a unilateral kidney function of <10% (hypoplasia, dysplasia, and atrophy, group 1) and those with a solitary kidney (agenesis, and multicystic dysplastic kidney, group 2).
  
  
  RESULTS
  A total of 126 patients (70 boys) were evaluated. Both the sizes of the functional kidney and functional kidney SDS values at diagnosis were greater in group 1 relative to group 2. At the end of the follow-up period, anthropometric values including functional kidney size were higher in group 2. Functional kidney size of 2 SDS above the normal was mostly predictive at age 17.5 months (odds ratio [OR] 5.06) and at a body height of 82 cm (OR 5.57).
  
  
  CONCLUSIONS
  The most determining factors for renal length SDS values were age and height. Solitary kidneys complete compensatory hypertrophy by 17.5 months of age, and after that their growth continues in parallel to normal growth.
authors.affiliation: Department of Pediatric Nephrology, Dokuz Eylul University, Faculty of Medicine, Izmir, Turkey. demetalaygut@yahoo.com
authors.forename: Demet
authors.initials: D
authors.lastname: Alaygut
authors.forename: Alper
authors.initials: A
authors.lastname: Soylu
authors.forename: Belde
authors.initials: B
authors.lastname: Kasap
authors.forename: Mehmet
authors.initials: M
authors.lastname: Türkmen
authors.forename: Handan
authors.initials: H
authors.lastname: Cakmakcı
authors.forename: Salih
authors.initials: S
authors.lastname: Kavukcu
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001284:Atrophy / Q000150:complications; D001827:Body Height; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000209:etiology / Q000503:physiopathology; D007223:Infant; D007668:Kidney / Q000002:abnormalities / Q000473:pathology* / Q000503:physiopathology*; D008297:Male; D021782:Multicystic Dysplastic Kidney / Q000150:complications; D016017:Odds Ratio; D009929:Organ Size; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D014718:Vesico-Ureteral Reflux / Q000209:etiology