title: Late effects of orbital enucleation and radiation on maxillofacial prosthetic rehabilitation: A clinical report.
abstract: The retinoblastoma is one of the most common tumors of the eye diagnosed in childhood. The treatment for patients with retinoblastoma includes surgical removal of the lesion along with adjunctive chemotherapy and radiotherapy. If the tumor is controlled, these treatments can have secondary adverse effects pertaining to the growth and development of orofacial structures in young patients. This clinical report describes the prosthetic rehabilitation of a patient who underwent enucleation followed by radiation therapy and adjunctive chemotherapy to treat the primary diagnosis of retinoblastoma. This therapy resulted in a combination of dental and facial growth and developmental abnormalities.
authors.affiliation: Maxillofacial Prosthetics Service, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
authors.forename: Supanut
authors.initials: S
authors.lastname: Tummawanit
authors.forename: Binit
authors.initials: B
authors.lastname: Shrestha
authors.forename: Sita
authors.initials: S
authors.lastname: Thaworanunta
authors.forename: Theerathavaj
authors.initials: T
authors.lastname: Srithavaj
mesh_terms: D000293:Adolescent; D017024:Chemotherapy, Adjuvant; D003779:Denture Design; D003828:Denture, Overlay; D005137:Eye, Artificial; D005146:Facial Asymmetry / Q000628:therapy; D005260:Female; D006801:Humans; D008313:Malocclusion, Angle Class III / Q000628:therapy; D008437:Maxilla / Q000002:abnormalities; D008445:Maxillofacial Development / Q000187:drug effects / Q000528:radiation effects; D009065:Mouth Rehabilitation; D020360:Neoadjuvant Therapy; D017233:Orbit Evisceration; D019736:Prostheses and Implants; D011474:Prosthesis Design; D018714:Radiotherapy, Adjuvant; D019572:Retinal Neoplasms / Q000601:surgery*; D012175:Retinoblastoma / Q000601:surgery*; D014071:Tooth Abnormalities / Q000628:therapy; D014087:Tooth Movement Techniques / Q000379:methods