title: Design and synthesis of chiral oxathiozinone scaffolds: efficient synthesis of hindered enantiopure sulfinamides and sulfinyl ketimines.
authors.affiliation: Department of Chemical Development, Boehringer Ingelheim Pharmaceuticals Inc., 900 Old Ridgebury Road, P.O. Box 368, Ridgefield, CT 06877, USA. steve.han@boehringer-ingelheim.com
authors.forename: Zhengxu S
authors.initials: ZS
authors.lastname: Han
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Herbage
authors.forename: Hari P R
authors.initials: HP
authors.lastname: Mangunuru
authors.forename: Yibo
authors.initials: Y
authors.lastname: Xu
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Jonathan T
authors.initials: JT
authors.lastname: Reeves
authors.forename: Joshua D
authors.initials: JD
authors.lastname: Sieber
authors.forename: Zhibin
authors.initials: Z
authors.lastname: Li
authors.forename: Philomen
authors.initials: P
authors.lastname: DeCroos
authors.forename: Yongda
authors.initials: Y
authors.lastname: Zhang
authors.forename: Guisheng
authors.initials: G
authors.lastname: Li
authors.forename: Ning
authors.initials: N
authors.lastname: Li
authors.forename: Shengli
authors.initials: S
authors.lastname: Ma
authors.forename: Nelu
authors.initials: N
authors.lastname: Grinberg
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Wang
authors.forename: Navneet
authors.initials: N
authors.lastname: Goyal
authors.forename: Dhileep
authors.initials: D
authors.lastname: Krishnamurthy
authors.forename: Bruce
authors.initials: B
authors.lastname: Lu
authors.forename: Jinhua J
authors.initials: JJ
authors.lastname: Song
authors.forename: Guijun
authors.initials: G
authors.lastname: Wang
authors.forename: Chris H
authors.initials: CH
authors.lastname: Senanayake
mesh_terms: D000438:Alcohols; D000588:Amines / Q000737:chemistry; D003499:Cyclic S-Oxides / Q000138:chemical synthesis*; D015195:Drug Design; D007097:Imines / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry*; D013237:Stereoisomerism; D013455:Sulfur / Q000737:chemistry*; D013696:Temperature; D013881:Thioridazine / Q000737:chemistry*; D014050:Toluene / Q000737:chemistry
chemical_list: D000438:Alcohols; D000588:Amines; D003499:Cyclic S-Oxides; D007097:Imines; D009570:Nitriles; C542835:ketimine; D014050:Toluene; D013455:Sulfur; D013881:Thioridazine