title: Statistical considerations for the development of prescriptive fetal and newborn growth standards in the INTERGROWTH-21st Project.
abstract: The INTERGROWTH-21(st) Project has in its mandate to develop prescriptive standards for fetal, neonatal and preterm post-neonatal growth. The project comprises three components: the Fetal Growth Longitudinal Study (FGLS), the Preterm Postnatal Follow-up Study (PPFS), and the Newborn Cross-Sectional Study (NCSS). We consider here the statistical aspects of the three components as they relate to the construction of these standards, in particular the sample size, and outline the principles that will guide the planned main analyses.
authors.affiliation: Centre for Statistics in Medicine, Wolfson College Annexe, University of Oxford, Oxford, UK.
authors.forename: D G
authors.initials: DG
authors.lastname: Altman
authors.forename: E O
authors.initials: EO
authors.lastname: Ohuma
mesh_terms: D001837:Body Weights and Measures; D002657:Child Development; D002985:Clinical Protocols; D003430:Cross-Sectional Studies / Q000379:methods; D003627:Data Interpretation, Statistical; D047109:Fetal Development; D057238:Growth Charts; D006801:Humans; D007223:Infant; D007231:Infant, Newborn / Q000254:growth & development*; D008137:Longitudinal Studies / Q000379:methods; D015233:Models, Statistical; D015337:Multicenter Studies as Topic / Q000379:methods*; D012107:Research Design; D018401:Sample Size; D016216:Ultrasonography, Prenatal
keywords: Sample size; fetal growth; longitudinal study; prescriptive standards, INTERGROWTH-21st; statistical aspects