title: Sweet's syndrome: a very rare association with pulmonary tuberculosis.
abstract: Mycobacterium tuberculosis infection is a common infection in developing countries, including India. It can induce several cutaneous reactions such as erythema nodosum, and erythema induratum; however, association of tuberculosis with Sweet's syndrome (also known as acute febrile neutrophilic dermatosis) is extremely rare. Here we present an interesting case of sputum-positive pulmonary tuberculosis with Sweet's syndrome. A 55-year-old female who was receiving a regimen of four antitubercular drugs (isoniazid, rifampicin, pyrazinamide, ethambutol- HRZE) for six weeks for sputum-positive pulmonary tuberculosis developed new onset high-grade fever for 15 days along with multiple reddish brown plaques and nodules involving the face as well as all four limbs of the body. Histopathology of the skin lesion was suggestive of Sweet's syndrome. The patient responded well to immunosuppressive steroid therapy.
authors.affiliation: Department of Medicine, North Bengal Medical College and Hospital, Siliguri, West Bengal, India. parthamed@yahoo.co.in
authors.forename: Partha Sarathi
authors.initials: PS
authors.lastname: Karmakar
authors.forename: Pasang Lahmu
authors.initials: PL
authors.lastname: Sherpa
authors.forename: Achintya Narayan
authors.initials: AN
authors.lastname: Ray
authors.forename: Bikram Kr
authors.initials: BK
authors.lastname: Saha
authors.forename: Tuhin
authors.initials: T
authors.lastname: Santra
authors.forename: Sanchita
authors.initials: S
authors.lastname: Saha
authors.forename: Indranil
authors.initials: I
authors.lastname: Chakrabarti
mesh_terms: D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007194:India; D008853:Microscopy; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D013902:Radiography, Thoracic; D012867:Skin / Q000473:pathology; D013256:Steroids / Q000627:therapeutic use; D016463:Sweet Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology
chemical_list: D007166:Immunosuppressive Agents; D013256:Steroids