title: [Asymptomatic myocardial infarction after non-cardiac surgery; importance of routine testing of troponin concentration].
abstract: Perioperative myocardial infarction (PMI) is associated with a high mortality rate. Detection of PMI, however, is difficult due to a lack of typical anginal symptoms associated with the use of strong analgesics. Also, characteristic changes on the electrocardiogram may be minimal and/or transient. Recent studies have shown that postoperative troponin elevation is a strong, independent predictor of short- and intermediate-term mortality. In this article, we illustrate the importance of routine troponin measurements after major non-cardiac surgery with two patient cases. Moreover, we provide a brief overview of current evidence on perioperative myocardial infarction, and highlight current and future perspectives of troponin measurements.
authors.affiliation: Universitair Medisch Centrum Utrecht, Afd. Cardiologie, Utrecht, the Netherlands. rgrobben@umcutrecht.nl
authors.forename: Remco B
authors.initials: RB
authors.lastname: Grobben
authors.forename: Judith A R
authors.initials: JA
authors.lastname: van Waes
authors.forename: Wilton A
authors.initials: WA
authors.lastname: van Klei
authors.forename: Hendrik M
authors.initials: HM
authors.lastname: Nathoe
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D011184:Postoperative Period; D013514:Surgical Procedures, Operative / Q000009:adverse effects*; D014336:Troponin / Q000097:blood*
chemical_list: D015415:Biomarkers; D014336:Troponin