title: Risk factors for a poor hematopoietic stem cell mobilization.
abstract: Poor mobilization is an important problem in autologous stem cell transplantation. We retrospectively reviewed the data of 165 mobilized patients to identify possible risk factors for a poor stem cell mobilization. 27 patients (16.4%) were categorized as poorly mobilized. The poor mobilization ratio differed according to diagnosis (lymphoma: 25.4%, acute leukemia: 15.4%, amyloidosis: 14.3%, and multiple myeloma: 9.6%). Being diagnosed as lymphoma (odds ratio [OR]=6.02, p=0.001), advanced age (OR=1.05, p=0.007) and increased weight (OR=1.03, p=0.03) were found as possible risk factors. Being diagnosed as lymphoma was shown to be the most important risk factor for a poor mobilization. Leukapheresis staff should be aware of the increased risk of a poor mobilization in lymphoma patients and remobilization methods should be considered from the beginning.
authors.affiliation: Ege University Medical School Hospital, Department of Hematology, 35100 Izmir, Turkey. Electronic address: ayhan.donmez@ege.edu.tr.
authors.forename: Ayhan
authors.initials: A
authors.lastname: Donmez
authors.forename: Fergun
authors.initials: F
authors.lastname: Yilmaz
authors.forename: Nihal
authors.initials: N
authors.lastname: Gokmen
authors.forename: Murat
authors.initials: M
authors.lastname: Tombuloglu
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult
keywords: Hematopoietic stem cell mobilization; Poor mobilization; Risk factors