title: Penile lesion with inguinal adenopathy after intravesical Bacillus Calmette-Guerin instillation therapy.
abstract: Intravesical Bacillus Calmette-Guérin (BCG) is widely used as an adjuvant therapy in the treatment of non-muscle-invasive bladder cancer. BCG is generally well tolerated, though localized and systemic infectious complications may occur. Infection of the glans and inguinal adenopathy are rare local complications of intravesical BCG therapy. Traumatic urethral catheterization is one of the main causes. We report the case of a 75-year-old male who developed granulomatous balanitis and enlarged inguinal lymph nodes after five cycles of intravesical BCG treatment for transitional cell carcinoma of the bladder. Histology revealed giant cell granuloma. Oral antituberculous treatment was initiated with subsequent full recovery of penile lesions and adenopathy. Physicians who administer BCG must be familiar with the possible complications and their adequate management and should inform patients about the side-effects accordingly.
authors.affiliation: Department of Urology, Dokuz Eylul University, School of Medicine, Izmir, Turkey.
authors.forename: Guven
authors.initials: G
authors.lastname: Aslan
authors.forename: Can
authors.initials: C
authors.lastname: Sevinc
authors.forename: Burcin
authors.initials: B
authors.lastname: Tuna
authors.forename: Sermin
authors.initials: S
authors.lastname: Ozkal
authors.forename: Kutsal
authors.initials: K
authors.lastname: Yorukoglu
keywords: Bacillus Calmette-Guerin; Bladder cancer; balanitis; complication; intravesical treatment