title: Concomitant herpes simplex virus and cytomegalovirus endotheliitis in immunocompetent patient.
abstract: A case of an immunocompetent 51-year-old healthy man with chronic recurrent disciform corneal oedema and hypertensive anterior uveitis in the right eye for 2 years was unresponsive to topical corticosteroid and systemic acyclovir. Diagnostic anterior chamber tapping was performed and viral DNA PCR was positive for both cytomegalovirus and herpes simplex virus. The patient was treated with both oral valganciclovir for 3 months and long-term oral acyclovir. His condition improved significantly after the treatment; intraocular pressure and anterior chamber inflammation were controlled and the remaining keratic precipitates in the cornea started to clear up.
authors.affiliation: Department of Ophthalmology, Chulalongkorn University, Bangkok, Thailand. ngamjitk@gmail.com
authors.forename: Ngamjit
authors.initials: N
authors.lastname: Kasetsuwan
authors.forename: Chulaluck
authors.initials: C
authors.lastname: Tangmonkongvoragul
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D015715:Corneal Edema / Q000188:drug therapy / Q000821:virology; D003587:Cytomegalovirus / Q000235:genetics; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy / Q000821:virology; D004279:DNA, Viral; D004728:Endothelium, Corneal / Q000473:pathology / Q000821:virology; D005128:Eye Diseases / Q000188:drug therapy / Q000473:pathology / Q000821:virology*; D006561:Herpes Simplex / Q000150:complications* / Q000188:drug therapy / Q000821:virology; D006801:Humans; D016849:Keratitis, Herpetic / Q000188:drug therapy / Q000821:virology; D008297:Male; D008875:Middle Aged; D018139:Simplexvirus / Q000235:genetics; D014605:Uveitis / Q000188:drug therapy / Q000821:virology
chemical_list: D000998:Antiviral Agents; D004279:DNA, Viral