title: Highly sensitive electrochemiluminescent cytosensing using carbon nanodot@Ag hybrid material and graphene for dual signal amplification.
abstract: Here we use functionalized carbon nanodots (C-dots) as novel electrochemiluminescence (ECL) probes and graphene nanosheets as signal amplification agents for highly sensitive and selective cancer cell detection. The ECL cytosensor shows superior cell-capture ability and exhibits a wide linear range and a low detection limit for cancer cells.
authors.affiliation: Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
authors.forename: Li
authors.initials: L
authors.lastname: Wu
authors.forename: Jiasi
authors.initials: J
authors.lastname: Wang
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.forename: Wen
authors.initials: W
authors.lastname: Li
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000378:metabolism*; D015374:Biosensing Techniques; D002244:Carbon / Q000737:chemistry*; D055664:Electrochemical Techniques; D005492:Folic Acid / Q000378:metabolism; D058972:Folic Acid Transporters / Q000378:metabolism; D006108:Graphite / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D061986:MCF-7 Cells; D051379:Mice; D041681:NIH 3T3 Cells; D053761:Nanocomposites / Q000737:chemistry*; D009369:Neoplasms / Q000175:diagnosis / Q000378:metabolism; D012834:Silver / Q000737:chemistry*
chemical_list: D014408:Biomarkers, Tumor; D058972:Folic Acid Transporters; D012834:Silver; D002244:Carbon; D006108:Graphite; D005492:Folic Acid