title: Comparison of efficacy and safety of laser in situ keratomileusis using 2 femtosecond laser platforms in contralateral eyes.
abstract: OBJECTIVE
  To compare the efficacy, predictability, and refractive outcomes of laser in situ keratomileusis (LASIK) using 2 femtosecond platforms for flap creation.
  
  
  METHODS
  Multisurgeon single center.
  
  
  METHODS
  Clinical trial.
  
  
  METHODS
  Bilateral femtosecond LASIK was performed using the Wavelight Allegretto Eye-Q 400 Hz excimer laser system. The Visumax femtosecond platform (Group 1) was used to create the LASIK flap in 1 eye, while the Intralase femtosecond platform (Group 2) was used to create the LASIK flap in the contralateral eye. The preoperative, 1-month, and 3-month postoperative visual acuities, refraction, and contrast sensitivity in the 2 groups were compared.
  
  
  RESULTS
  The study enrolled 45 patients. Three months after femtosecond LASIK, 79.5% of eyes in Group 1 and 82.1% in Group 2 achieved an uncorrected distance visual acuity of 20/20 (P=.808). The mean efficacy index was 0.97 in Group 1 and 0.98 in Group 2 at 3 months (P=.735); 89.7% of eyes in Group 1 and 84.6% of eyes in Group 2 were within ± 0.50 diopter of emmetropia at 3 months (P=.498). No eye in either group lost more than 2 lines of corrected distance visual acuity. The mean safety index at 3 months was 1.11 in Group 1 and 1.10 in Group 2 (P=.570).
  
  
  CONCLUSIONS
  The results of LASIK with both femtosecond lasers were similar, and both platforms produced efficacious and predictable LASIK outcomes.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: Singapore National Eye Center, the Singapore Eye Research Institute, National University of Singapore, Singapore.
authors.forename: Mohamad
authors.initials: M
authors.lastname: Rosman
authors.forename: Reece C
authors.initials: RC
authors.lastname: Hall
authors.forename: Cordelia
authors.initials: C
authors.lastname: Chan
authors.forename: Andy
authors.initials: A
authors.lastname: Ang
authors.forename: Jane
authors.initials: J
authors.lastname: Koh
authors.forename: Hla Myint
authors.initials: HM
authors.lastname: Htoon
authors.forename: Donald T H
authors.initials: DT
authors.lastname: Tan
authors.forename: Jodhbir S
authors.initials: JS
authors.lastname: Mehta
mesh_terms: D000328:Adult; D015350:Contrast Sensitivity / Q000502:physiology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications; D011446:Prospective Studies; D012029:Refraction, Ocular / Q000502:physiology; D013524:Surgical Flaps; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult