title: Persistent photosensitivity after allergic contact dermatitis to epoxy resin.
abstract: BACKGROUND
  Persistent photosensitivity after allergic contact dermatitis (ACD) to epoxy resin has rarely been described.
  
  
  OBJECTIVE
  The aim of this study was to create awareness that ACD to epoxy may be a trigger for persistent photosensitivity.
  
  
  METHODS
  We present a series of 5 patients who developed ACD to epoxy resin and later a photodistributed eczematous eruption when exposed to sunlight, with a documented decrease in minimal erythema dose to UVA and UVB.
  
  
  RESULTS
  The age of patients ranged from 34 to 71 years, and there were 3 men and 2 women. Each patient had occupational exposure to epoxy. Symptoms of epoxy ACD preceded photosensitivity by 5 months to 12 years in 3 cases and occurred simultaneously in 2 cases. Patch testing to epoxy resin was positive in all patients. Phototesting revealed a decreased minimal erythema dose to UVA and UVB in each of the 3 patients who were phototested. Photopatch testing was positive for epoxy resin in 1 of the 2 patients tested. All patients remained photosensitive for at least 2 years after diagnosis, with only 1 case of photosensitivity resolving with extended avoidance of epoxy.
  
  
  CONCLUSIONS
  There is an association between ACD to epoxy resin and development of persistent photosensitivity. Possible mechanisms to explain the relationship between the 2 phenomena are discussed.
authors.affiliation: Division of Dermatology and Cutaneous Sciences, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Tiffany
authors.initials: T
authors.lastname: Kwok
authors.forename: Cheryl F
authors.initials: CF
authors.lastname: Rosen
authors.forename: Frances J
authors.initials: FJ
authors.lastname: Storrs
authors.forename: Edmund
authors.initials: E
authors.lastname: Lobel
authors.forename: Joel G
authors.initials: JG
authors.lastname: DeKoven
mesh_terms: D000328:Adult; D000368:Aged; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D004853:Epoxy Resins / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests / Q000379:methods; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects*
chemical_list: D004853:Epoxy Resins