title: Brain magnetic resonance imaging findings suggestive of widespread white matter involvement in children with Streptococcus mitis meningitis.
abstract: Streptococcus mitis (S. mitis) is a rare cause of meningitis in immunocompetent children. It has been described in patients with neurosurgical procedure, previous spinal anesthesia and immunodeficiency. We report two childhood cases of S. mitis meningitis. The children were previously healthy. One of the patients had poor oral hygiene and the other had a history of sinusitis. Both of them had encephalopathy and signs of meningeal irritation at presentation. Widespread cerebral white matter lesions were found on brain magnetic resonance imaging. The lesions disappeared and encephalopathy recovered with antibiotic and immunomodulatory treatment.
authors.affiliation: Department of Pediatric Neurology, Gaziantep Children's Hospital, Gaziantep, Turkey. ulyis@yahoo.com
authors.forename: Uluç
authors.initials: U
authors.lastname: Yiş
authors.forename: Kürşat Bora
authors.initials: KB
authors.lastname: Carman
authors.forename: Reyhan
authors.initials: R
authors.lastname: Yiş
authors.forename: Umit
authors.initials: U
authors.lastname: Derundere
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008581:Meningitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D009413:Nerve Fibers, Myelinated / Q000382:microbiology*; D009910:Oral Hygiene; D012852:Sinusitis / Q000382:microbiology; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D034361:Streptococcus mitis / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D016756:Immunoglobulins, Intravenous