title: miR-34a and the cardiomyopathy of senescence: SALT PNUTS, SALT PNUTS!
abstract: The search for eternal youth is age old. In a recent Nature paper, Boon et al. (2013) describe DNA damage mechanisms and cardiac senescence provoked by miR-34a and its target, PNUTS. Interrupting this pathway may prevent age- and stress-induced cardiac degeneration.
authors.affiliation: Center for Pharmacogenomics, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. gdorn@dom.wustl.edu
authors.forename: Gerald W
authors.initials: GW
authors.lastname: Dorn