title: Cardiac device-related invasive aspergilloma assessed by live/real time three-dimensional transthoracic echocardiography.
abstract: Cardiac device-related infection caused by Aspergillus species is a rare finding associated with high mortality. Prompt recognition and treatment is imperative, but difficult as blood cultures are often negative and diagnosis requires a high index of suspicion. Live/real time three-dimensional transthoracic echocardiography (3DTTE) provides incremental knowledge in the characterization of valvular vegetations. Here, we provide a detailed description of an invasive cardiac device-related infection caused by Aspergillus fumigatus using 3DTTE. Findings described here highlight the role for 3DTTE in the prompt diagnosis of invasive cardiac Aspergillus infections as well as surgical planning in such cases.
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
authors.forename: Donald
authors.initials: D
authors.lastname: Clark
authors.forename: Mustafa I
authors.initials: MI
authors.lastname: Ahmed
authors.forename: Aylin
authors.initials: A
authors.lastname: Sungur
authors.forename: Tuğba
authors.initials: T
authors.lastname: Kemaloğluöz
authors.forename: Kruti Jayesh
authors.initials: KJ
authors.lastname: Mehta
authors.forename: Hari Prakash
authors.initials: HP
authors.lastname: Diddi
authors.forename: Rohit
authors.initials: R
authors.lastname: Tandon
authors.forename: Vishnu V
authors.initials: VV
authors.lastname: Reddy
authors.forename: Navin C
authors.initials: NC
authors.lastname: Nanda
authors.forename: David C
authors.initials: DC
authors.lastname: McGiffin
mesh_terms: D001228:Aspergillosis / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000628:therapy; D003199:Computer Systems; D003937:Diagnosis, Differential; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009205:Myocarditis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D010138:Pacemaker, Artificial / Q000009:adverse effects*; D016459:Prosthesis-Related Infections / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000628:therapy; D016896:Treatment Outcome
keywords: Aspergilloma; echocardiography; fungal infections; fungal infections of the heart; three-dimensional echocardiography; three-dimensional transthoracic echocardiography