title: [Detection of high risk human papillomavirus by hybrid capture II® according cytological findings in women treated for squamous intraepithelial lesions of the cervix, period 2006/2010].
abstract: OBJECTIVE
  To determinate the frequency of high risk human papillomavirus (HR-HPV) by hybrid capture II (r) (CH II(r)), according cytology results in women treated for squamous intraepithelial lesions of the cervix (SIL).
  
  
  METHODS
  A descriptive cross-sectional study of a series of cases that included 122 women treated, 79 (75%) for low grade SIL (LSIL) and 43 (35%) for high grade SIL (HSIL) attending at the HPV Laboratory at the Health Sciences Research Institute (IICS), National University of Asunción (UNA), for post-treatment control during period 2006/2010.
  
  
  RESULTS
  A total of 28% (34/122) of women treated for SIL were positive for HR-HPV, detecting viral infection in 20% of women with no SIL (NSIL) (22/108), in 83% of women with LSIL (10/12) and in 100% of women with HSIL (2/2). Of 34 women positive for HR-HPV, 10 women (29%) had high values (100 pg / mL or more) of relative viral load, detecting an increase of positive cases with severity of the lesion (28% NSIL, 30% LSIL, 50% HSIL).
  
  
  CONCLUSIONS
  HR-HPV detection by CH II(r) and high relative viral load values especially in women with NSIL could help to identify treated women at risk of developing recurrence, thereby contributing to strengthening the cervical cancer prevention program.
authors.affiliation: Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay.
authors.forename: Pamela
authors.initials: P
authors.lastname: Mongelós
authors.forename: Malvina
authors.initials: M
authors.lastname: Páez
authors.forename: Isabel
authors.initials: I
authors.lastname: Rodriguez-Riveros
authors.forename: Graciela
authors.initials: G
authors.lastname: Giménez
authors.forename: Amalia
authors.initials: A
authors.lastname: Castro
authors.forename: Laura
authors.initials: L
authors.lastname: Mendoza
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D015344:DNA Probes, HPV; D005260:Female; D006801:Humans; D030361:Papillomavirus Infections / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D012307:Risk Factors; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000628:therapy / Q000821:virology*; D002578:Uterine Cervical Dysplasia / Q000473:pathology* / Q000821:virology*
chemical_list: D015344:DNA Probes, HPV