title: Fast determination of sulfonamides and their acetylated metabolites from environmental water based on magnetic molecularly imprinted polymers.
abstract: Group-selective magnetic molecularly imprinted polymers (MMIPs) that can extract four widely used sulfonamide antibiotics and their acetylated metabolites from environmental water were synthesized in this study. The MMIPs with saturation magnetization value of 16.7 emu g(-1) could be separated from the environmental water samples easily by the application of an adscititious magnetic field, reducing the time consumption of pretreatment. The extraction conditions were evaluated, and optimal extraction conditions were as follows: extraction time, 25 min; amount of polymers, 90 mg; washing solvent, 30 % methanol aqueous solution; and elution solvent, methanol-acetic acid (95:5, v/v). The target analytes were detected by liquid chromatography-tandem mass spectrometry, and the detection limits of the method are in the range of 0.38-1.32 ng L(-1). The relative standard deviations of intra- and inter-day are in the range of 1.3-6.8 % and 1.7-9.1 %, respectively. The proposed method is suitable for the analysis of environmental water samples.
authors.affiliation: College of Chemistry, Jilin University, Changchun, 130012, China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Chen
authors.forename: Yiqun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Bo
authors.initials: B
authors.lastname: Gao
authors.forename: Yang
authors.initials: Y
authors.lastname: Xu
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhao
authors.forename: Juan
authors.initials: J
authors.lastname: Hou
authors.forename: Jin
authors.initials: J
authors.lastname: Yan
authors.forename: Guijie
authors.initials: G
authors.lastname: Li
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Lan
authors.initials: L
authors.lastname: Ding
authors.forename: Jie
authors.initials: J
authors.lastname: Ding
authors.forename: Chun
authors.initials: C
authors.lastname: Zhao
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis*; D004784:Environmental Monitoring / Q000379:methods*; D008280:Magnetics; D054802:Molecular Imprinting; D011108:Polymers / Q000032:analysis / Q000737:chemistry; D013449:Sulfonamides / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D000900:Anti-Bacterial Agents; D011108:Polymers; D013449:Sulfonamides; D014874:Water Pollutants, Chemical