title: Outbreak of acute Chagas disease associated with oral transmission in the Rio Negro region, Brazilian Amazon.
abstract: BACKGROUND
  Chagas disease is considered as emerging in the Brazilian Amazon, usually occurring in acute outbreaks.
  
  
  METHODS
  We describe 17 cases of acute Chagas disease in Rio Negro, Amazonas.
  
  
  RESULTS
  There were 15 males (average age, 31.3 years), all positive for Trypanosoma cruzi in fresh blood smear examination, and 14 positive by xenodiagnosis and PCR. The top clinical manifestations were fever, asthenia, abdominal pain, and palpitations. Electrocardiograms featured low-voltage QRS, anterosuperior divisional block, and right bundle branch block associated with anterosuperior divisional block.
  
  
  CONCLUSIONS
  All patients had consumed açaí products from Monte Alegre in the rural area around Santa Izabel do Rio Negro, Brazil.
authors.affiliation: Gerência de Leishmaniose e Gerencia de Entomologia, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM.
authors.forename: Rita de Cássia de
authors.initials: Rde C
authors.lastname: Souza-Lima
authors.forename: Maria das Graças Vale
authors.initials: Md
authors.lastname: Barbosa
authors.forename: José Rodrigues
authors.initials: JR
authors.lastname: Coura
authors.forename: Ana Ruth Lima
authors.initials: AR
authors.lastname: Arcanjo
authors.forename: Adelaide da Silva
authors.initials: Ada S
authors.lastname: Nascimento
authors.forename: João Marcos Bemfica Barbosa
authors.initials: JM
authors.lastname: Ferreira
authors.forename: Laylah Kelre
authors.initials: LK
authors.lastname: Magalhães
authors.forename: Bernardino Cláudio de
authors.initials: BC
authors.lastname: Albuquerque
authors.forename: Guilherme Alfredo Novelino
authors.initials: GA
authors.lastname: Araújo
authors.forename: Jorge Augusto de Oliveira
authors.initials: JA
authors.lastname: Guerra
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000913:Antibodies, Protozoan / Q000097:blood*; D001938:Brazil / Q000453:epidemiology; D014355:Chagas Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission*; D002648:Child; D004196:Disease Outbreaks; D005260:Female; D016266:Food Parasitology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014349:Trypanosoma cruzi / Q000235:genetics / Q000276:immunology; D055815:Young Adult
chemical_list: D000913:Antibodies, Protozoan