title: Renin-angiotensin blockade combined with natriuretic peptide system augmentation: novel therapeutic concepts to combat heart failure.
authors.affiliation: Department of Epidemiology and Preventive Medicine, Monash Center of Cardiovascular Research and Education in Therapeutics, Monash University, Alfred Hospital, Melbourne, VIC 3004, Australia.
authors.forename: Thomas G
authors.initials: TG
authors.lastname: von Lueder
authors.forename: S Jeson
authors.initials: SJ
authors.lastname: Sangaralingham
authors.forename: Bing H
authors.initials: BH
authors.lastname: Wang
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Kompa
authors.forename: Dan
authors.initials: D
authors.lastname: Atar
authors.forename: John C
authors.initials: JC
authors.lastname: Burnett
authors.forename: Henry
authors.initials: H
authors.lastname: Krum
mesh_terms: D017398:Alternative Splicing / Q000187:drug effects / Q000502:physiology; D000613:Aminobutyrates / Q000627:therapeutic use; D057911:Angiotensin Receptor Antagonists / Q000627:therapeutic use; D001713:Biphenyl Compounds; D015198:Designer Drugs / Q000737:chemistry / Q000627:therapeutic use; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D019332:Endothelin-1 / Q000187:drug effects; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D020097:Natriuretic Peptide, Brain / Q000502:physiology; D020098:Natriuretic Peptide, C-Type / Q000502:physiology; D045265:Natriuretic Peptides / Q000737:chemistry / Q000502:physiology*; D015260:Neprilysin / Q000037:antagonists & inhibitors / Q000502:physiology; D007703:Peptidyl-Dipeptidase A / Q000187:drug effects; D011480:Protease Inhibitors / Q000627:therapeutic use; D011945:Receptors, Angiotensin / Q000187:drug effects; D012084:Renin-Angiotensin System / Q000187:drug effects* / Q000502:physiology*; D012910:Snake Venoms / Q000737:chemistry; D013777:Tetrazoles / Q000627:therapeutic use; D000068756:Valsartan
chemical_list: D000613:Aminobutyrates; D057911:Angiotensin Receptor Antagonists; D001713:Biphenyl Compounds; D015198:Designer Drugs; D004338:Drug Combinations; D019332:Endothelin-1; D045265:Natriuretic Peptides; D011480:Protease Inhibitors; D011945:Receptors, Angiotensin; D012910:Snake Venoms; D013777:Tetrazoles; D020097:Natriuretic Peptide, Brain; D020098:Natriuretic Peptide, C-Type; D000068756:Valsartan; C575835:cenderitide; D007703:Peptidyl-Dipeptidase A; D015260:Neprilysin; C549068:sacubitril and valsartan sodium hydrate drug combination
keywords: BNP; angiotensin II; heart failure; natriuretic peptides; neprilysin; renin-angiotensin system