title: Posterior chamber phakic intraocular lens to correct myopia: long-term follow-up.
abstract: OBJECTIVE
  To evaluate the long-term safety and efficacy of a refractive phakic intraocular lens (pIOL) (PRL) to correct moderate to high myopia.
  
  
  METHODS
  Department of Ophthalmology, University Medicine Charité Berlin, Berlin, Germany.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, intraocular pressure, endothelial cell loss, and adverse events were evaluated.
  
  
  RESULTS
  The study enrolled 53 eyes (mean spherical equivalent [SE] -12.17 diopters [D] ± 4.12 [SD]) of 29 patients. The mean age was 34.6 ± 9.2 years and the mean follow-up, 86 ± 21.2 months. The mean UDVA improved from 1.37 ± 0.28 logMAR preoperatively to 0.14 ± 0.19 logMAR at the last postoperative visit (P<.05). The mean CDVA improved from 0.10 ± 0.18 logMAR to -0.01 ± 0.09 logMAR (P<.05). The overall mean efficacy index and mean safety index were 0.9 and 1.21, respectively, at the last follow-up visit. The mean endothelial cell loss at the last follow-up was 6.4%. The complications were slight posterior chamber (PC) pIOL decentration (5 eyes, 9.4%), severe PC pIOL decentration resulting in pIOL removal (1 eye, 1.8%), glaucoma (4 eyes, 7.5%), clinically significant cortical lens opacification resulting in cataract surgery (4 eyes, 7.5%), clinically asymptomatic anterior subcapsular cataract formation (6 eyes, 11.3%), and retinal detachment (2 eyes, 3.8%).
  
  
  CONCLUSIONS
  Posterior chamber phakic pIOL implantation to correct moderate to high myopia provided predictable and stable refractive results but with a high rate of serious complications over the long term.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: Departments of Ophthalmology, University Medicine Charité Berlin, Berlin, Germany. necip.torun@charite.de
authors.forename: Necip
authors.initials: N
authors.lastname: Torun
authors.forename: Eckart
authors.initials: E
authors.lastname: Bertelmann
authors.forename: Matthias K J
authors.initials: MK
authors.lastname: Klamann
authors.forename: Anna-Karina
authors.initials: AK
authors.lastname: Maier
authors.forename: Anja
authors.initials: A
authors.lastname: Liekfeld
authors.forename: Johannes
authors.initials: J
authors.lastname: Gonnermann
mesh_terms: D000328:Adult; D055954:Corneal Endothelial Cell Loss / Q000175:diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D007431:Intraoperative Complications; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000503:physiopathology / Q000601:surgery*; D054120:Phakic Intraocular Lenses; D011183:Postoperative Complications; D012029:Refraction, Ocular / Q000502:physiology; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult