title: The desorption process of macromolecules adsorbed on interfaces: the force spectroscopy approach.
abstract: They're flexible and sticky: While investigations of the very stiff DNA molecular conformation on surfaces have been made, the equivalent for more typical macromolecules is complicated by their shorter persistance length. A gentle detachment study with a polymer bound to an SFM tip allows the forces between the polymer and surface to be probed; the detachement force required depends on the surface conformation, whether only a small loop or a long tail must be peeled from the surface, as shown by the cartoon.
authors.affiliation: Dipartimento di Scienze Nefrologiche, Ospedale S. Orsola, Bologna, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Conti
authors.forename: Y
authors.initials: Y
authors.lastname: Bustanji
authors.forename: G
authors.initials: G
authors.lastname: Falini
authors.forename: P
authors.initials: P
authors.lastname: Ferruti
authors.forename: S
authors.initials: S
authors.lastname: Stefoni
authors.forename: B
authors.initials: B
authors.lastname: Samorì
mesh_terms: D000327:Adsorption; D046911:Macromolecular Substances / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D015394:Molecular Structure; D013499:Surface Properties
chemical_list: D046911:Macromolecular Substances