title: [Residue of organic fluorine pollutants in hair and nails collected from Tianjin].
abstract: In order to explore the residue and distributions of organic fluorine pollutants in hair and nails, the residue levels of total fluorine (TF), extractable organic fluorine (EOF) and perfluorinated chemicals (PFCs) in hair and nails collected from Tianjin adults were measured by the cyclic neutron activation analysis (CNAA) combined with the high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The results showed that inorganic fluorine (mean: 2.0 mg.kg-1, 4.5 mg.kg-1) was the primary fluorine in TF while EOF(mean: 0.7 mg.kg-1, 1.8 mg.kg-1) was minor. The average amount of identified fluorine (IF) was 0.038 mg.kg-1 in hair and 0.047 mg.kg-1 in nails, accounting or 7.1% (2.6%-16%) and 3.5% (1.1%-11%) of EOF, respectively, which indicated that more than 84% of EOF was unknown. The major residue in hair and nails were medium-and short-chain PFCs,in which perfluorooctane sulfonate, perfluorooctanoic acid and perfluorononanoic acid were the main species. TF, EOF and IF levels in dyed and permed hair were significantly higher than untreated hair (P <0.05), and the concentrations of Sigma PFCs in hair and nails showed no difference between genders. With significantly higher levels of sigma PFCs and PFOS residues than hair (P <0.01), nails could potentially become a more sensitive bioindicator for the exposure level of PFCs in human.
authors.affiliation: College of Food Engineering and Biotechnology, Tianjin University of Science and Techqology, Tianjin 300457, China. 123naicha@sina.com
authors.forename: Dan
authors.initials: D
authors.lastname: Yao
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.forename: Zhi-Fang
authors.initials: ZF
authors.lastname: Chai
authors.forename: Jin-Can
authors.initials: JC
authors.lastname: Shen
authors.forename: Bo
authors.initials: B
authors.lastname: Yang
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Wang
authors.forename: Guo-Qing
authors.initials: GQ
authors.lastname: Liu
mesh_terms: D000328:Adult; D017738:Alkanesulfonic Acids / Q000032:analysis; D002210:Caprylates / Q000032:analysis; D002681:China; D002851:Chromatography, High Pressure Liquid; D004781:Environmental Exposure / Q000032:analysis; D004785:Environmental Pollutants / Q000032:analysis*; D005260:Female; D005461:Fluorine / Q000032:analysis*; D005466:Fluorocarbons / Q000032:analysis; D006197:Hair / Q000737:chemistry*; D006801:Humans; D008297:Male; D009262:Nails / Q000737:chemistry*; D009930:Organic Chemicals / Q000032:analysis*; D053719:Tandem Mass Spectrometry
chemical_list: D017738:Alkanesulfonic Acids; D002210:Caprylates; D004785:Environmental Pollutants; D005466:Fluorocarbons; D009930:Organic Chemicals; D005461:Fluorine; C023036:perfluorooctanoic acid; C076994:perfluorooctane sulfonic acid