title: Treatment of osteoid osteoma with CT-guided percutaneous radiofrequency thermoablation.
abstract: Osteoid osteoma is a benign bone tumor with a male predominance occurring mainly in children and young adults. The most common symptom is intermittent pain that worsens at night and is at least partially relieved by nonsteroidal anti-inflammatory drugs. The purpose of this study was to assess the long-term effectiveness of computed tomography-guided percutaneous radiofrequency thermoablation in patients with a minimum follow-up of 2 years. Twenty patients with osteoid osteoma (15 men and 5 women) with a mean age of 20.7 years (range, 4-61 years; 12 patients aged 20 years or younger) underwent computed tomography-guided percutaneous radiofrequency thermoablation. Lesion sites were the femur (n=9), tibia (n=7), pelvis (n=1), talus (n=1), cuneiform bone (n=1), and humerus (n=1). Mean follow-up was 44 months (range, 3-106 months). Pain relief was significant in 95% of patients; it disappeared within 24 hours in 14 patients, within 3 days in 4, and within 7 days in 1. The patient with persistent symptoms underwent another percutaneous radiofrequency thermoablation procedure that was successful. The difference between pre- and postoperative pain was significant (P ≤ .01). No recurrences occurred. Computed tomography-guided percutaneous radiofrequency thermoablation is a safe, minimally invasive, and economical procedure with high technical and clinical success rates, and it effectively and durably enhances quality of life.
authors.affiliation: Clinic Orthopaedic, Marche Polytechnic University, Ancona Hospital, Via Conca 71, 60100 Ancona, Italy. l.depalma@univpm.it
authors.forename: Luigi
authors.initials: L
authors.lastname: de Palma
authors.forename: Roberto
authors.initials: R
authors.lastname: Candelari
authors.forename: Ettore
authors.initials: E
authors.lastname: Antico
authors.forename: Rocco
authors.initials: R
authors.lastname: Politano
authors.forename: Eugenio
authors.initials: E
authors.lastname: Luniew
authors.forename: Maurizio
authors.initials: M
authors.lastname: Giordanengo
authors.forename: Silvio
authors.initials: S
authors.lastname: Di Giansante
authors.forename: Mario
authors.initials: M
authors.lastname: Marinelli
authors.forename: Enrico
authors.initials: E
authors.lastname: Paci
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery*; D017115:Catheter Ablation / Q000009:adverse effects / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000009:adverse effects / Q000379:methods*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010017:Osteoma, Osteoid / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery*; D010149:Postoperative Pain / Q000209:etiology / Q000517:prevention & control; D025321:Surgery, Computer-Assisted / Q000009:adverse effects / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome; D055815:Young Adult