title: Cytomegalovirus retinitis in immunocompetent patients: case reports and literature review.
abstract: OBJECTIVE
  The purpose of this study was to examine 2 cases of cytomegalovirus (CMV) retinitis, occuring in 2 immunocompentent adult patients.
  
  
  METHODS
  Case selection and literature review.
  
  
  RESULTS
  Both patients cited significantly decreased vision despite systemic, topical, and/or local corticosteroid use. Neither patient was using high-dose immunosuppressant therapy at the time of diagnostic testing. Both patients exhibited confirmed CMV infection via polymerase chain reaction DNA testing. Oral antivirals were employed and have stabilized both patients.
  
  
  CONCLUSIONS
  The cases described herein serve to inform ophthalmologists of the urgent need to include CMV in their differential when encountering an immunocompetent adult with significant comorbidities or with a history of previous exposure. Proper treatment is heavily reliant on proper diagnosis.
authors.forename: Alaa
authors.initials: A
authors.lastname: Radwan
authors.forename: Jamie Lynne
authors.initials: JL
authors.lastname: Metzinger
authors.forename: David M
authors.initials: DM
authors.lastname: Hinkle
authors.forename: C Stephen
authors.initials: CS
authors.lastname: Foster
mesh_terms: D003587:Cytomegalovirus / Q000235:genetics*; D017726:Cytomegalovirus Retinitis / Q000175:diagnosis* / Q000276:immunology / Q000821:virology; D004279:DNA, Viral / Q000032:analysis*; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction
chemical_list: D004279:DNA, Viral