title: Update on the collaborative interventions for circulation and depression (COINCIDE) trial: changes to planned methodology of a cluster randomized controlled trial of collaborative care for depression in people with diabetes and/or coronary heart disease.
abstract: BACKGROUND
  The COINCIDE trial aims to evaluate the effectiveness and cost-effectiveness of a collaborative care intervention for depression in people with diabetes and/or coronary heart disease attending English general practices.
  
  
  METHODS
  This update details changes to the cluster and patient recruitment strategy for the COINCIDE study. The original protocol was published in Trials (http://www.trialsjournal.com/content/pdf/1745-6215-13-139.pdf). Modifications were made to the recruitment targets in response to lower-than-expected patient recruitment at the first ten general practices recruited into the study. In order to boost patient numbers and retain statistical power, the number of general practices recruited was increased from 30 to 36. Follow-up period was shortened from 6 months to 4 months to ensure that patients recruited to the trial could be followed up by the end of the study.
  
  
  RESULTS
  Patient recruitment began on the 01/05/2012 and is planned to be completed by the 30/04/2013. Recruitment for general practices was completed on 31/10/2012, by which time the target of 36 practices had been recruited. The main trial results will be published in a peer-reviewed journal.
  
  
  CONCLUSIONS
  The data from the trial will provide evidence on the effectiveness and cost-effectiveness of collaborative care for depression in people with diabetes and/or coronary heart disease.
  
  
  BACKGROUND
  
  
  
  BACKGROUND
  ISRCTN80309252.
authors.affiliation: Greater Manchester Collaboration for Leadership in Applied Health Research and Care, Institute of Population Health and Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PL, UK. peter.a.coventry@manchester.ac.uk
authors.forename: Peter A
authors.initials: PA
authors.lastname: Coventry
authors.forename: Karina
authors.initials: K
authors.lastname: Lovell
authors.forename: Chris
authors.initials: C
authors.lastname: Dickens
authors.forename: Peter
authors.initials: P
authors.lastname: Bower
authors.forename: Carolyn
authors.initials: C
authors.lastname: Chew-Graham
authors.forename: Andrea
authors.initials: A
authors.lastname: Cherrington
authors.forename: Charlotte
authors.initials: C
authors.lastname: Garrett
authors.forename: Chris J
authors.initials: CJ
authors.lastname: Gibbons
authors.forename: Clare
authors.initials: C
authors.lastname: Baguley
authors.forename: Kate
authors.initials: K
authors.lastname: Roughley
authors.forename: Isabel
authors.initials: I
authors.lastname: Adeyemi
authors.forename: Chris
authors.initials: C
authors.lastname: Keyworth
authors.forename: Waquas
authors.initials: W
authors.lastname: Waheed
authors.forename: Mark
authors.initials: M
authors.lastname: Hann
authors.forename: Linda
authors.initials: L
authors.lastname: Davies
authors.forename: Farheen
authors.initials: F
authors.lastname: Jeeva
authors.forename: Chris
authors.initials: C
authors.lastname: Roberts
authors.forename: Sarah
authors.initials: S
authors.lastname: Knowles
authors.forename: Linda
authors.initials: L
authors.lastname: Gask
mesh_terms: D002985:Clinical Protocols; D015897:Comorbidity; D003299:Cooperative Behavior; D003327:Coronary Disease / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology / Q000628:therapy*; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology / Q000628:therapy*; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology / Q000628:therapy*; D004739:England / Q000453:epidemiology; D058006:General Practice; D006801:Humans; D033183:Interdisciplinary Communication; D010348:Patient Care Team; D018579:Patient Selection; D012107:Research Design; D018401:Sample Size; D013997:Time Factors; D016896:Treatment Outcome