title: Aerobic oxidation of indole carbinols using Fe(NO3)3·9H2O/TEMPO/NaCl as catalysts.
abstract: A practical aerobic oxidation of indole carbinols using Fe(NO3)3·9H2O/TEMPO/NaCl in DCE at room temperature and atmospheric pressure of oxygen affording aldehydes or ketones in good to excellent yields was developed. Furthermore, when using the industrially favored solvent toluene instead of DCE and air instead of pure oxygen, this protocol also works smoothly, demonstrating its high potential for possible industrial application.
authors.affiliation: Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, 3663 North Zhongshan Lu, Shanghai 200062, PR China.
authors.forename: Jinxian
authors.initials: J
authors.lastname: Liu
authors.forename: Shengming
authors.initials: S
authors.lastname: Ma
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D002384:Catalysis; D003497:Cyclic N-Oxides / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry; D000432:Methanol / Q000031:analogs & derivatives*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D012965:Sodium Chloride / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D003497:Cyclic N-Oxides; D005290:Ferric Compounds; D007211:Indoles; D007659:Ketones; D012965:Sodium Chloride; C030374:indole; D010100:Oxygen; C003959:TEMPO; D000432:Methanol