title: Adverse pregnancy outcomes in women with nausea and vomiting of pregnancy.
abstract: OBJECTIVE
  To examine the influence of nausea and vomiting of pregnancy (NVP) on pregnancy outcomes.
  
  
  METHODS
  Outcomes were compared for primigravidas with a current singleton gestation enrolled at <20 weeks' gestation in a maternity risk screening and education program (n = 81 486). Patient-reported maternal characteristics and pregnancy outcomes were compared for women with and without NVP and within the NVP group for those with and without poor weight gain.
  
  
  RESULTS
  6.4% of women reported NVP as a pregnancy complication. Women reporting NVP were more likely to be younger, obese, single and smoke. They had higher rates of preterm delivery, pregnancy-induced hypertension and low birth weight <2500 g. Almost one-quarter of women with NVP had lower than recommended weight gain. Poor weight gain was associated with a higher incidence of adverse outcomes. Obesity, tobacco use and poor pregnancy weight gain independently increased the odds of an adverse outcome.
  
  
  CONCLUSIONS
  NVP and subsequent poor weight gain may be associated with adverse pregnancy outcomes.
authors.affiliation: Department of Obstetrics and Gynecology, Carolinas Medical Center , Charlotte, NC , USA .
authors.forename: Lorene
authors.initials: L
authors.lastname: Temming
authors.forename: Albert
authors.initials: A
authors.lastname: Franco
authors.forename: Niki
authors.initials: N
authors.lastname: Istwan
authors.forename: Debbie
authors.initials: D
authors.lastname: Rhea
authors.forename: Cheryl
authors.initials: C
authors.lastname: Desch
authors.forename: Gary
authors.initials: G
authors.lastname: Stanziano
authors.forename: Saju
authors.initials: S
authors.lastname: Joy
mesh_terms: D000328:Adult; D000367:Age Factors; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000453:epidemiology; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D016015:Logistic Models; D048968:Morning Sickness / Q000453:epidemiology*; D009765:Obesity / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000453:epidemiology; D012847:Single Person / Q000706:statistics & numerical data; D012907:Smoking / Q000453:epidemiology; D014481:United States / Q000453:epidemiology; D015430:Weight Gain