title: Totally cystic schwannoma of the lumbar spine.
abstract: A schwannoma is a benign tumor arising from a schwann cell and occurs mainly in the nerve sheath in the intradural extramedullary region. Schwannomas have been well described as occurring in the lumbar spine, but total cystic degeneration of schwannomas is rarely reported. The authors describe the clinical and radiographic evaluations and treatment of a rare case of an intraextradural totally cystic schwannoma on the lumbar spine.Two patients reported a history of 6 to 12 months of pain accompanied by weakness in the lower extremities. On examination, 1 patient had bilateral lower-extremity muscle strength graded at 4/5, and magnetic resonance imaging revealed a cystic schwannoma (1.5 × 2.0 cm in the sagittal dimension) at L2-L3. The other patient had a right lower-extremity muscle strength graded at 3/5, and magnetic resonance imaging revealed a cystic schwannoma (2.0 × 3.0 cm in the sagittal dimension) at L4-L5. The patients underwent operative treatment, and the tumors were completely removed, as were the filum terminale adhered to the tumor. Pedicle screws were used to maintain stability of the lumbar spine. Gross examination of the tumors showed yellowish-white soft contents. Histologic examination confirmed that they were benign totally cystic schwannomas. Postoperatively, the patients' neurologic symptoms completely resolved.Cystic schwannomas can be diagnosed using preoperative magnetic resonance imaging. The filum terminale cut off the tumor walls did not cause the clinical symptoms in the 2 patients.
authors.affiliation: Department of Spine Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
authors.forename: Desheng
authors.initials: D
authors.lastname: Wu
authors.forename: Zhaoyu
authors.initials: Z
authors.lastname: Ba
authors.forename: Yufeng
authors.initials: Y
authors.lastname: Huang
authors.forename: Weidong
authors.initials: W
authors.lastname: Zhao
authors.forename: Bin
authors.initials: B
authors.lastname: Shen
authors.forename: Heng
authors.initials: H
authors.lastname: Kan
mesh_terms: D001845:Bone Cysts / Q000473:pathology* / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009442:Neurilemmoma / Q000473:pathology* / Q000601:surgery*; D010027:Osteotomy / Q000379:methods*; D013123:Spinal Fusion / Q000379:methods; D013125:Spinal Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome