title: Contribution of maternal chronic experimental hepatic disease to the development of nonspecific cell resistance in the progeny.
abstract: Morphofunctional pecularities of the bone marrow neutrophil maturation were studied in the progeny of female rats with chronic experimental toxic hepatitis, similar to hepatitis B by morphological, biochemical, and physiological characteristics. The lysosomal, phagocytic, and killing activities of cells were reduced during the morphologically identifiable stages of neutrophilopoiesis (myeloblasts, promyelocytes, myelocytes, metamyelocytes, stab and segmented neutrophils).
authors.affiliation: Chelyabinsk State Medical Academy, Ministry of Health and Social Development of the Russian Federation, Russia.
authors.forename: G V
authors.initials: GV
authors.lastname: Bryukhin
authors.forename: N V
authors.initials: NV
authors.lastname: Nevzorova
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000276:immunology; D002465:Cell Movement; D056486:Chemical and Drug Induced Liver Injury / Q000276:immunology*; D005260:Female; D007113:Immunity, Innate; D008247:Lysosomes / Q000502:physiology; D008297:Male; D009504:Neutrophils / Q000276:immunology* / Q000378:metabolism*; D010587:Phagocytosis; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D051381:Rats; D017208:Rats, Wistar; D013211:Staphylococcus aureus / Q000276:immunology