title: [Solitary pulmonary lesion developed after the resection of primary lung cancer].
abstract: The purpose of this study was to evaluate the characteristics of solitary pulmonary lesion developed after the resection of primary lung cancer and the outcome. Between 1990 and 2011, 1,004 patients underwent complete resection for primary lung cancer in our hospital and we retrospectively analyzed 53 patients with a history of primary lung cancer resection who had a solitary pulmonary lesion. Pulmonary resections were performed in 43 patients. Wedge resection and segmentectomy were performed in 42( 98%) of them. There was no operative death. The diagnosis was 2nd primary lung cancer in 28 patients, recurrent lesion in 9, and benign lesions in 6. Malignant tumor ratio of resected cases was 86%.Other unresected 10 cases were not diagnosed historogically and 9 of them underwent radiation therapy. The 5-year survival rate was 57.3% in those with 2nd primary lung cancer, 55.5% in those with recurrent lesion, and 64.3% in those with undiagnosed-unresected lesions( no significant difference). It is important to take a surgical approach for a diagnosis and to treat with standard therapy for both 2nd primary lung cancer and recurrent lesion. Sublobar resection may be adequate. In patients with a undiagnosed nodule who were not able to have 2nd surgery, radiation therapy may be permitted and effective.
authors.affiliation: Department of Thoracic Surgery, Koseiren Takaoka Hospital, Takaoka, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Saito
authors.forename: Munehisa
authors.initials: M
authors.lastname: Takata
authors.forename: Noriyoshi
authors.initials: N
authors.lastname: Yashiki
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery*; D008297:Male; D009364:Neoplasm Recurrence, Local; D016609:Neoplasms, Second Primary; D011013:Pneumonectomy; D012189:Retrospective Studies; D003074:Solitary Pulmonary Nodule / Q000401:mortality / Q000473:pathology*