title: Effects of hypothetical type 2 diabetes genetic testing on parents' efforts to prevent diabetes in children.
abstract: OBJECTIVE
  To examine the effect of hypothetical genetic susceptibility test results on diabetic parents' intention to prevent type 2 diabetes (T2D) in their children.
  
  
  METHODS
  Parents with T2D indicated their intention to prevent T2D in their youngest child at baseline and after a hypothetical positive and negative T2D genetic test result. We calculated mean/median "preventive intention scores" for each scenario and examined the association between parents' score change and parent/child characteristics.
  
  
  RESULTS
  A total of 63% of parents reported that their child had "almost no risk" or "slight risk" of developing T2D. Parents' median baseline preventive intention score was 8. It increased to 10 after a positive test result and decreased to 5 after a negative test result.
  
  
  CONCLUSIONS
  Negative T2D genetic susceptibility test results may decrease diabetic parents' intentions to prevent T2D for their children. Future research studies in a real-life clinical context should examine this phenomenon.
authors.affiliation: Child Health Evaluation and Research, University of Michigan, Ann Arbor, MI 48109-5456, USA. btarini@umich.edu
authors.forename: Beth A
authors.initials: BA
authors.lastname: Tarini
authors.forename: William H
authors.initials: WH
authors.lastname: Herman
authors.forename: Joyce M
authors.initials: JM
authors.lastname: Lee
mesh_terms: D001294:Attitude to Health; D002648:Child; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control* / Q000523:psychology*; D005260:Female; D005820:Genetic Testing / Q000706:statistics & numerical data*; D006801:Humans; D033182:Intention; D008297:Male; D008875:Middle Aged; D010290:Parents / Q000523:psychology*; D012307:Risk Factors
keywords: children; diabetes mellitus; genetic testing; type 2 diabetes; vignettes