title: Cord blood endothelial colony-forming cells from newborns with congenital diaphragmatic hernia.
abstract: Endothelial colony-forming cells (ECFCs) are decreased in the cord blood of preterm infants with moderate-to-severe bronchopulmonary dysplasia. We quantified ECFCs from infants with congenital diaphragmatic hernia, a neonatal disorder with severe lung hypoplasia. Unlike newborns who develop bronchopulmonary dysplasia, those with congenital diaphragmatic hernia had increased and highly-proliferative cord blood ECFCs.
authors.affiliation: Pediatric Heart Lung Center, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA. Christopher.Baker@UCDenver.edu
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Baker
authors.forename: Claudine P
authors.initials: CP
authors.lastname: Black
authors.forename: Sharon L
authors.initials: SL
authors.lastname: Ryan
authors.forename: Vivek
authors.initials: V
authors.lastname: Balasubramaniam
authors.forename: Steven H
authors.initials: SH
authors.lastname: Abman
mesh_terms: D049109:Cell Proliferation; D002478:Cells, Cultured; D042783:Endothelial Cells / Q000502:physiology; D005260:Female; D005312:Fetal Blood / Q000166:cytology*; D006548:Hernia, Diaphragmatic / Q000097:blood; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D007958:Leukocyte Count; D007963:Leukocytes, Mononuclear / Q000502:physiology; D008297:Male; D013234:Stem Cells / Q000502:physiology
keywords: BPD; Bronchopulmonary dysplasia; CDH; Congenital diaphragmatic hernia; ECFC; EPC; Endothelial colony-forming cell; Endothelial progenitor cell; MNC; Mononuclear cells