title: Optical profiles of cathode ray tube and liquid crystal display monitors: implication in cutaneous phototoxicity in photodynamic therapy.
abstract: Recent clinical reports suggest that overexposure to light emissions generated from cathode ray tube (CRT) and liquid crystal display (LCD) color monitors after topical or systemic administration of a photosensitizer could cause noticeable skin phototoxicity. In this study, we examined the light emission profiles (optical irradiance, spectral irradiance) of CRT and LCD monitors under simulated movie and video game modes. Results suggest that peak emissions and integrated fluence generated from monitors are clinically relevant and therefore prolonged exposure to these light sources at a close distance should be avoided after the administration of a photosensitizer or phototoxic drug.
authors.affiliation: Department of Electrical Engineering, University of Colorado Denver, Denver, Colorado 80217, USA.
authors.forename: Tim C
authors.initials: TC
authors.lastname: Lei
authors.forename: Srinivas
authors.initials: S
authors.lastname: Pendyala
authors.forename: Larry
authors.initials: L
authors.lastname: Scherrer
authors.forename: Buhong
authors.initials: B
authors.lastname: Li
authors.forename: Gregory F
authors.initials: GF
authors.lastname: Glazner
authors.forename: Zheng
authors.initials: Z
authors.lastname: Huang
mesh_terms: D003198:Computer Simulation; D016288:Computer Terminals; D004781:Environmental Exposure / Q000009:adverse effects*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D050866:Liquid Crystals / Q000737:chemistry; D008954:Models, Biological; D010778:Photochemotherapy / Q000009:adverse effects*; D017319:Photosensitizing Agents / Q000009:adverse effects*; D011829:Radiation Dosage; D011874:Radiometry; D018570:Risk Assessment; D012879:Skin Physiological Phenomena / Q000187:drug effects* / Q000528:radiation effects*
chemical_list: D017319:Photosensitizing Agents