title: Left dominant arrhythmogenic cardiomyopathy: a morbid association of ventricular arrhythmias and unexplained infero-lateral T-wave inversion.
abstract: Left-dominant arrhythmogenic cardiomyopathy is a subtype of arrhythmogenic right ventricular cardiomyopathy characterized by early predominant left ventricular involvement. Α 34-year-old man presented with palpitations and a history of frequent ventricular extrasystoles of both LBBB and RBBB configuration. Cardiac workup revealed repolarization abnormalities at infero-lateral leads in the absence of diagnostic structural/functional alterations or obstructive coronary artery disease. Six months later he died suddenly. Histopathology was diagnostic for arrhythmogenic right ventricular cardiomyopathy affecting predominantly the left ventricle at subepicardial/midwall myocardial layers. Thus, ventricular arrhythmias accompanied by unexplained infero-lateral T-wave inversion should warn of a possible morbid association underlying left-dominant arrhythmogenic cardiomyopathy.
authors.affiliation: Department of Cardiology, University Hospital of Heraklion, Heraklion, Greece. alexanderproton@gmail.com
authors.forename: Alexandros
authors.initials: A
authors.lastname: Protonotarios
authors.forename: Alexandros
authors.initials: A
authors.lastname: Patrianakos
authors.forename: Elpida
authors.initials: E
authors.lastname: Spanoudaki
authors.forename: Georgios
authors.initials: G
authors.lastname: Kochiadakis
authors.forename: Emmanouel
authors.initials: E
authors.lastname: Michalodimitrakis
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Vardas
mesh_terms: D000328:Adult; D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000150:complications* / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004562:Electrocardiography / Q000379:methods*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D017180:Tachycardia, Ventricular / Q000150:complications* / Q000175:diagnosis*; D018487:Ventricular Dysfunction, Left / Q000150:complications* / Q000175:diagnosis*