title: Genotype 4 hepatitis e virus in france: an autochthonous infection with a more severe presentation.
abstract: Among hepatitis E virus (HEV) infections diagnosed in 2011 by the French Reference Centre for HEV, 9 were due to genotype 4, which until recently was limited to Asia. Sequences from autochthonous cases formed a single cluster very similar to Belgian swine sequences. Clinical presentation differed from genotype 3 infections.
authors.affiliation: Hôpital Paul Brousse, AP-HP, Villejuif, France.
authors.forename: Asma
authors.initials: A
authors.lastname: Jeblaoui
authors.forename: Stephanie
authors.initials: S
authors.lastname: Haim-Boukobza
authors.forename: Eric
authors.initials: E
authors.lastname: Marchadier
authors.forename: Camelia
authors.initials: C
authors.lastname: Mokhtari
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Roque-Afonso
mesh_terms: D000328:Adult; D000368:Aged; D016000:Cluster Analysis; D005260:Female; D005602:France / Q000453:epidemiology; D005838:Genotype; D016751:Hepatitis E / Q000453:epidemiology* / Q000473:pathology* / Q000821:virology; D016752:Hepatitis E virus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D017422:Sequence Analysis, DNA
chemical_list: D012367:RNA, Viral
keywords: HEV; HEV genotype 4; epidemiology; virulence