title: Patients who require non-cardiac surgery in acute coronary syndrome.
abstract: The coexistence of an acute coronary syndrome (ACS) and non-cardiac surgery (NCS) in an individual patient can be summarized in two challenging clinical scenarios for the treating physician: 1) Post-operative patients who develop ACS and 2) Patients with ACS who subsequently require NCS. Both settings are characterized by a struggle on the part of treating physicians attempting to optimize antithrombotic therapies for ACS while minimizing post-surgical bleeding risk. In this review we address specific clinical issues related to patients with coexistent NCS and ACS, discussing possible management strategies balancing ischemic and bleeding risk in these complex patient scenarios.
authors.affiliation: Columbia University Medical Center/New York Presbyterian Hospital and The Cardiovascular Research Foundation, 161 Fort Washington Ave, 6th Floor, New York, NY 10032, USA.
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Wessler
authors.forename: Ajay J
authors.initials: AJ
authors.lastname: Kirtane
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications / Q000628:therapy*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011182:Postoperative Care / Q000379:methods; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000517:prevention & control; D017410:Practice Guidelines as Topic
chemical_list: D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors