title: Concise solid-phase synthesis of inverse poly(amidoamine) dendrons using AB2 building blocks.
abstract: A concise solid-phase synthesis of inverse poly(amidoamine) dendrons was developed. Upon introduction of AB2-type monomers, each dendron generation was constructed via one reaction. G2 to G5 dendrons were constructed in a peptide synthesizer in 93%, 89%, 82%, and 78% yields, respectively, within 5 days.
authors.affiliation: Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
authors.forename: Adela Ya-Ting
authors.initials: AY
authors.lastname: Huang
authors.forename: Ching-Hua
authors.initials: CH
authors.lastname: Tsai
authors.forename: Hsing-Yin
authors.initials: HY
authors.lastname: Chen
authors.forename: Hui-Ting
authors.initials: HT
authors.lastname: Chen
authors.forename: Chi-Yu
authors.initials: CY
authors.lastname: Lu
authors.forename: Yu-Ting
authors.initials: YT
authors.lastname: Lin
authors.forename: Chai-Lin
authors.initials: CL
authors.lastname: Kao
mesh_terms: D000478:Alkylation; D000588:Amines / Q000737:chemistry; D001331:Automation; D002264:Carboxylic Acids / Q000737:chemistry; D050091:Dendrimers / Q000138:chemical synthesis* / Q000737:chemistry; D011073:Polyamines / Q000737:chemistry*; D060327:Solid-Phase Synthesis Techniques
chemical_list: D000588:Amines; D002264:Carboxylic Acids; D050091:Dendrimers; C531249:Poly(amidoamine); D011073:Polyamines