title: Pyoderma gangrenosum: guideline for wound practitioners.
abstract: Pyoderma gangrenosum (PG) is an atypical ulceration of the skin with unknown aetiology, usually associated with autoimmune systemic illnesses and haematological malignancies. Diagnosis is based on clinical suspicion and exclusion of other conditions. Treatment options vary greatly, ranging from conservative local and systemic immunosuppression to surgical measures, including amputation, but none is shown to be universally effective. Currently no guideline regarding escalation of treatment exists. Based on a review of the current literature and three illustrative cases of PG, a working treatment guideline is presented for wound practitioners.
authors.affiliation: University of Tasmania, Australia.
authors.forename: S
authors.initials: S
authors.lastname: Ratnagobal
authors.forename: S
authors.initials: S
authors.lastname: Sinha
mesh_terms: D000369:Aged, 80 and over; D001458:Bandages; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D017511:Pyoderma Gangrenosum / Q000473:pathology / Q000628:therapy*; D016038:Skin Transplantation
chemical_list: D007166:Immunosuppressive Agents