title: Botanical origin of dietary supplements labeled as "Kwao Keur", a folk medicine from Thailand.
abstract: In the course of our study on the quality of dietary supplements in Japan, both the internal transcribed spacer (ITS) sequence of nrDNA and the rps16 intron sequence of cpDNA of products labeled as "Kwao Keur" were investigated. As a result, the DNA sequence of Pueraria candollei var. mirifica, which is the source plant of Kwao Keur, was observed in only about half of the products. Inferred from the determined sequences, source plants in the other products included Medicago sativa, Glycyrrhiza uralensis, Pachyrhizus erosus, and Ipomoea batatas, etc. These inferior products are estimated to lack the efficacy implied by their labeling. In order to guarantee the quality of dietary supplements, it is important to identify the source materials exactly; in addition, an infrastructure that can exclude these inferior products from the market is needed for the protection of consumers from potential damage to their health and finances. The DNA analysis performed in this study is useful for this purpose.
authors.affiliation: Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya, Tokyo, 158-8501, Japan, t-maruya@nihs.go.jp.
authors.forename: Takuro
authors.initials: T
authors.lastname: Maruyama
authors.forename: Maiko
authors.initials: M
authors.lastname: Kawamura
authors.forename: Ruri
authors.initials: R
authors.lastname: Kikura-Hanajiri
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Goda
mesh_terms: D058893:DNA Barcoding, Taxonomic; D018744:DNA, Plant / Q000032:analysis; D021903:DNA, Ribosomal Spacer / Q000032:analysis; D019587:Dietary Supplements / Q000032:analysis / Q000145:classification* / Q000592:standards; D006801:Humans; D007438:Introns; D008519:Medicine, Traditional; D010802:Phylogeny; D028321:Plant Preparations / Q000032:analysis / Q000145:classification* / Q000592:standards; D029908:Pueraria / Q000737:chemistry / Q000145:classification* / Q000235:genetics; D011786:Quality Control; D021521:Ribotyping; D013785:Thailand
chemical_list: D018744:DNA, Plant; D021903:DNA, Ribosomal Spacer; D028321:Plant Preparations