title: Outcomes of complete radical hysterectomy in early-stage cervical cancer patients with intra-operative detection of nodal metastases.
abstract: OBJECTIVE
  To determine the overall 5-year survival rate and treatment-related complications in stage IB-IIA cervical cancer patients with intra-operative detection of pelvic node metastases who underwent complete radical hysterectomy and systematic lymphadenectomy.
  
  
  METHODS
  The medical records of FIGO stage IB-IIA cervical cancer patients who underwent radical hysterectomy and pelvic lymphadenectomy in Rajavithi Hospital between January 1985 and December 2006 were retrospectively reviewed. Of the 247 node-positive stage IB-IIA cervical cancer patients, 121 patients displayed evidence of intra-operative detection and underwent complete radical hysterectomy with systematic lymphadenectomy. These 121 patients were reviewed of which 107 were in stage IB and 14 were in stage IIA. Overall 5-year survival rate and treatment-related complications were investigated.
  
  
  RESULTS
  The median follow-up period was 117 months (range 60-312 months). Of the 121 stage IB-IIA cervical cancer
  
  
  METHODS
  with intra-operative detection of pelvic node metastases who underwent complete radical hysterectomy and pelvic lymphadenectomy, the overall 5-year survival rate was 70.5%. The major treatment-related complications were intraoperative hemorrhage and post-operative bladder atony which accounted for 43.0% and 10.7%, respectively.
  
  
  CONCLUSIONS
  Early-stage cervical cancer patients with intra-operative detection of pelvic node metastases who underwent complete radical hysterectomy had favorable survival outcomes and manageable complications.
authors.affiliation: Department of Obstetrics and Gynecology Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand. suphetgyn@hotmail.com
authors.forename: Suphet
authors.initials: S
authors.lastname: Tuipae
authors.forename: Chayada
authors.initials: C
authors.lastname: Wongsuwan
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000473:pathology*; D009367:Neoplasm Staging; D011183:Postoperative Complications; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery*