title: [Recent development of understanding and psychiatric care on schizophrenia].
abstract: Recent development of understanding and psychiatric care on schizophrenia during past 30 years was reviewed. Slight brain volume reduction during early several years of the disease and association of psychotic symptoms with excess dopamine release in striatum were confirmed. A discovery of duration of untreated psychosis (DUP) has encouraged early intervention, hope for recovery from schizophrenia and liberation from old Kraepelin concept.
authors.affiliation: Tokyo Metropolitan Matsuzawa Hospital.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Okazaki
mesh_terms: D014150:Antipsychotic Agents / Q000627:therapeutic use; D004298:Dopamine / Q000378:metabolism; D018479:Early Intervention, Educational / Q000379:methods; D006801:Humans; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D004298:Dopamine