title: Two novel innovanoside dimers from Daphne aurantiaca and a concise total synthesis of diinnovanoside A.
abstract: Chemical examination of the methanolic extract from the stem bark of Daphne aurantiaca led to the isolation of two innovanoside dimers (1 and 2) with an unusual four-membered cyclobutane ring, together with the isoinnovanoside 3. Their chemical structures and configurations were elucidated by extensive spectral analysis and synthesis.
authors.affiliation: Department of Natural Product Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, People's Republic of China.
authors.forename: Shuang
authors.initials: S
authors.lastname: Liang
authors.forename: Shan-Xiang
authors.initials: SX
authors.lastname: Liu
authors.forename: Hui-Zi
authors.initials: HZ
authors.lastname: Jin
authors.forename: Lei
authors.initials: L
authors.lastname: Shan
authors.forename: Shi-Chong
authors.initials: SC
authors.lastname: Yu
authors.forename: Yun-Heng
authors.initials: YH
authors.lastname: Shen
authors.forename: Hui-Liang
authors.initials: HL
authors.lastname: Li
authors.forename: Qiu-Ye
authors.initials: QY
authors.lastname: Wu
authors.forename: Qing-Yan
authors.initials: QY
authors.lastname: Sun
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Zhang
mesh_terms: D018360:Crystallography, X-Ray; D003503:Cyclobutanes / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D032364:Daphne / Q000737:chemistry*; D019281:Dimerization; D005960:Glucosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D008958:Models, Molecular; D015394:Molecular Structure; D010936:Plant Extracts / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D003503:Cyclobutanes; D005960:Glucosides; D010936:Plant Extracts; D011753:Pyrones