title: BDNF and memory processing.
abstract: Brain-derived neurotrophic factor has emerged as one of the most important molecules involved in memory. Its wide role in different types of memories that depend on different structures as well as its involvement in distinct memory stages points at BDNF as one likely target to treat cognitive impairments and anxiety-related memory disorders. However, regulation of BDNF expression is very complex as well as its modes of action. Here we describe the latest research carried out on the function of BDNF in memory to illustrate such complexity. This article is part of the Special Issue entitled 'BDNF Regulation of Synaptic Structure, Function, and Plasticity'.
authors.affiliation: Instituto de Biologia Celular y Neurociencias, Facultad de Medicina, UBA, Argentina.
authors.forename: Pedro
authors.initials: P
authors.lastname: Bekinschtein
authors.forename: Martin
authors.initials: M
authors.lastname: Cammarota
authors.forename: Jorge H
authors.initials: JH
authors.lastname: Medina
mesh_terms: D000818:Animals; D019208:Brain-Derived Neurotrophic Factor / Q000502:physiology*; D006801:Humans; D008568:Memory / Q000502:physiology*
chemical_list: D019208:Brain-Derived Neurotrophic Factor
keywords: Hippocampus; Long-term memory; Memory persistence; Neurotrophins; Prefrontal cortex