title: Prevalence of Oculo-auriculo-vertebral Spectrum in Dermolipoma.
abstract: OBJECTIVE
  To describe the observed frequency of oculo-auriculo-vertebral spectrum (OAVS) in patients with dermolipoma.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  Patients with primary presentation of ocular dermolipoma.
  
  
  METHODS
  All patients with ocular dermolipoma or lipodermoid were identified from the authors' clinical databases from 1990 to 2011 inclusive. Case notes were reviewed retrospectively for the gender and age of presentation, the laterality of dermolipoma, and features of OAVS.
  
  
  METHODS
  The frequency of OAVS in patients with dermolipoma, the severity of the OAVS phenotype, and other concurrent ophthalmic features observed.
  
  
  RESULTS
  Thirty-four patients (24 females) presented with dermolipoma at ages ranging from 6 months to 57 years (mean, 20 years; median, 16 years). Twelve patients (35.5%) had features of OAVS (10 patients with dermolipoma had ipsilateral OAVS and 2 patients had contralateral features of OAVS). Ten patients with dermolipoma had hemifacial microsomia, and 2 patients had features of Goldenhar's syndrome. None of the patients had bilateral dermolipoma and OAVS. Other associated ophthalmic features were limbal dermoids (2 cases), lateral canthal coloboma (3 cases), and facial nerve palsy (1 case).
  
  
  CONCLUSIONS
  Dermolipoma is an independent ocular association of OAVS that is more commonly observed than previously reported. It is an ocular feature in both the milder and more complex forms of the spectrum.
  
  
  BACKGROUND
  The authors have no proprietary or commercial interest in any materials discussed in this article.
authors.affiliation: Royal Victorian Eye and Ear Hospital, Orbital Plastics and Lacrimal Unit, East Melbourne, Victoria, Australia. jwujinkhong@gmail.com
authors.forename: Jwu Jin
authors.initials: JJ
authors.lastname: Khong
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Hardy
authors.forename: Alan A
authors.initials: AA
authors.lastname: McNab
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006053:Goldenhar Syndrome / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D008067:Lipoma / Q000453:epidemiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence; D012189:Retrospective Studies; D014739:Victoria / Q000453:epidemiology; D055815:Young Adult