title: [Expressions of SIgA and alpha 1-AR in benign prostatic hyperplasia combined with chronic prostatitis and their implications].
abstract: OBJECTIVE
  To explore the expressions of SIgA and alpha l-AR in benign prostatic hyperplasia (BPH) complicated by chronic prostatitis (CP) and their implications.
  
  
  METHODS
  According to the preoperative findings of expressed prostatic secretion (EPS), transrectal prostate ultrasonography, prostate-specific antigen (PSA), international prostate symptom score (IPSS), clinical symptoms, chronic pelvic pain syndrome (CPPS) and postoperative histopathology, 62 cases of BPH pathologically confirmed after transurethral plasma kinetic resection of the prostate (PKRP) were divided into a BPH group (n = 32) and a BPH + CP group (n = 30). The expressions of SIgA and alpha 1-AR in the prostate tissue were determined by immunohistochemistry and PT-PCR.
  
  
  RESULTS
  Of the 62 cases, 30 were found to be BPH + CP, and the other 32 to be BPH. The expressions of SIgA and alpha1-AR were significantly higher in the BPH + CP than in the BPH group (0.380 8 +/- 0.144 3 vs 0.295 4 +/- 0.008 4 and 0.440 5 +/- 0.104 1 vs 0.383 2 +/- 0.013 6, P < 0.05).
  
  
  CONCLUSIONS
  The upregulated expressions of SIgA and alpha1-AR expression in BPH complicated by CP suggest a certain association between CP and BPH, and that inflammation may be a pathogenic factor of BPH and correlate with its pathological development.
authors.affiliation: Department of Urology, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou, Gansu 730050, China. 634809757@qq.com
authors.forename: Wei-Jun
authors.initials: WJ
authors.lastname: Gao
authors.forename: Yang-Min
authors.initials: YM
authors.lastname: Wang
authors.forename: Chang-Hai
authors.initials: CH
authors.lastname: Wang
authors.forename: Xu-Kai
authors.initials: XK
authors.lastname: Yang
authors.forename: Lin
authors.initials: L
authors.lastname: Wan
authors.forename: Wei-Ping
authors.initials: WP
authors.lastname: Li
mesh_terms: D000368:Aged; D002908:Chronic Disease; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000378:metabolism* / Q000473:pathology; D011470:Prostatic Hyperplasia / Q000150:complications / Q000378:metabolism* / Q000473:pathology; D011472:Prostatitis / Q000150:complications / Q000378:metabolism* / Q000473:pathology; D011944:Receptors, Androgen / Q000378:metabolism*
chemical_list: C410798:AR protein, human; D007071:Immunoglobulin A, Secretory; D011944:Receptors, Androgen