title: Comparison of diagnostic sensitivity of C-arm CT, DSA and CT in detecting small HCC.
abstract: OBJECTIVE
  To compare the detection rate of 64-slice CT, digital subtraction angiography (DSA) and C-arm computed tomography (C-arm CT) in small lesions with a diameter ≤3.0 cm of hepatocellular carcinoma (HCC).
  
  
  METHODS
  Sixty-six patients with HCC underwent 64-slice CT, DSA, and C-arm CT, and were followed up by lipiodol CT two weeks after transcatheter arterial chemoembolization (TACE). Whose result was used as diagnostic reference. The number of detected lesions with diameter ≤3.0 cm in each imaging modality was counted independently by 4 radiologists.
  
  
  RESULTS
  A total of 174 lesions out of the 66 patients were confirmed by lipiodol CT, among which 47.7% were detected by 64-slice CT, 82.2% by DSA, and 97.1% by C-arm CT. McNemar test showed the statistical difference in detection rate between each two methods of CT, DSA and C-arm CT (all p<0.0001). All lesions were further classified into 3 groups (group A, B, C) according to the diameter (≤1cm, 1-2cm, 2-3cm), where C-arm CT showed significantly higher diagnostic sensitivity in group A and B.
  
  
  CONCLUSIONS
  Compared to 64-slice CT and DSA, C-arm CT has the best sensitivity by detecting small lesions of HCC, and thus may play a guiding role in TACE procedure.
authors.forename: Jiasheng
authors.initials: J
authors.lastname: Zheng
authors.forename: Jianjun
authors.initials: J
authors.lastname: Li
authors.forename: Xiongwei
authors.initials: X
authors.lastname: Cui
authors.forename: Hui
authors.initials: H
authors.lastname: Ye
authors.forename: Linchao
authors.initials: L
authors.lastname: Ye
mesh_terms: D000328:Adult; D000368:Aged; D015901:Angiography, Digital Subtraction / Q000379:methods*; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000628:therapy; D016461:Chemoembolization, Therapeutic; D004998:Ethiodized Oil; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D004998:Ethiodized Oil