title: Physiological levels of glucose induce membrane vesicle secretion and affect the lipid and protein composition of Yersinia pestis cell surfaces.
abstract: Yersinia pestis grown with physiologic glucose increased cell autoaggregation and deposition of extracellular material, including membrane vesicles. Membranes were characterized, and glucose had significant effects on protein, lipid, and carbohydrate profiles. These effects were independent of temperature and the biofilm-related locus pgm and were not observed in Yersinia pseudotuberculosis.
authors.affiliation: School of Food Science, University of Idaho, Moscow, Idaho, USA.
authors.forename: Anna M
authors.initials: AM
authors.lastname: Kolodziejek
authors.forename: Allan B
authors.initials: AB
authors.lastname: Caplan
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Bohach
authors.forename: Andrzej J
authors.initials: AJ
authors.lastname: Paszczynski
authors.forename: Scott A
authors.initials: SA
authors.lastname: Minnich
authors.forename: Carolyn J
authors.initials: CJ
authors.lastname: Hovde
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D018441:Biofilms; D005075:Biological Evolution; D002462:Cell Membrane; D005947:Glucose / Q000378:metabolism*; D008855:Microscopy, Electron, Scanning; D008969:Molecular Sequence Data; D005423:Siphonaptera / Q000382:microbiology*; D014774:Virulence; D037521:Virulence Factors / Q000737:chemistry / Q000378:metabolism; D015010:Yersinia pestis / Q000737:chemistry* / Q000472:pathogenicity / Q000502:physiology* / Q000648:ultrastructure; D015011:Yersinia pseudotuberculosis / Q000737:chemistry / Q000472:pathogenicity / Q000502:physiology / Q000648:ultrastructure
chemical_list: D037521:Virulence Factors; D005947:Glucose