title: Review of recent guidelines and consensus statements on hereditary angioedema therapy with focus on self-administration.
abstract: Consensus meetings and the resulting recommendations shape treatment choices in rare diseases such as hereditary angioedema (HAE) because they combine the experience of prescribing physicians and the patients who are receiving therapy. Self-administration of HAE therapy was recognised as a potential treatment option in the first consensus publication in 2003. Recent studies have confirmed that self-administration of therapy resolves attacks quickly, safely and minimises burden of disease; however, the discovery of inconsistent treatment approaches is a concern and warrants investigation into the barriers that prevent adherence with current recommendations.
authors.affiliation: Department of Biomedical and Clinical Sciences, University of Milan and Luigi Sacco Hospital, Milan, Italy. marco.cicardi@unimi.it
authors.forename: M
authors.initials: M
authors.lastname: Cicardi
authors.forename: T J
authors.initials: TJ
authors.lastname: Craig
authors.forename: I
authors.initials: I
authors.lastname: Martinez-Saguer
authors.forename: J
authors.initials: J
authors.lastname: Hébert
authors.forename: H J
authors.initials: HJ
authors.lastname: Longhurst
mesh_terms: D054179:Angioedemas, Hereditary / Q000188:drug therapy*; D003174:Complement C1 Inactivator Proteins / Q000008:administration & dosage*; D003245:Consensus Statements as Topic; D017408:Guidelines as Topic; D006801:Humans; D010349:Patient Compliance; D012646:Self Administration / Q000379:methods / Q000592:standards
chemical_list: D003174:Complement C1 Inactivator Proteins