title: [How to interpret the results of immunological tests for the diagnosis of tuberculosis in child].
abstract: New available immunologic tests for tuberculosis (TB) diagnosis are Interferon-gamma release assay (IGRA). In adults these tests showed a higher specificity than tuberculin skin test (TST) but their superior sensitivity compared to TST sensitivity has not been proved yet. In children, interpretation of results remains disputed, especially in those <5 years. Hereby we report the most recent literature data for use and interpretation of IGRA is results in children.
authors.affiliation: Dipartimento di Scienze, Università di Firenze, Firenze, Italia. giulia.remaschi@gmail.com
authors.forename: G
authors.initials: G
authors.lastname: Remaschi
authors.forename: E
authors.initials: E
authors.lastname: Chiappini
authors.forename: F
authors.initials: F
authors.lastname: Bonsignori
authors.forename: R
authors.initials: R
authors.lastname: Mazzantini
authors.forename: L
authors.initials: L
authors.lastname: Galli
authors.forename: M
authors.initials: M
authors.lastname: De Martino
mesh_terms: D002648:Child; D006801:Humans; D059425:Interferon-gamma Release Tests / Q000379:methods; D015201:Meta-Analysis as Topic; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000175:diagnosis; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000276:immunology