title: Cold atmospheric plasma devices for medical issues.
abstract: Cold atmospheric plasma science is an innovative upcoming technology for the medical sector. The plasma composition and subsequent effects on cells, tissues and pathogens can vary enormously depending on the plasma source, the plasma settings and the ambient conditions. Cold atmospheric plasmas consist of a highly reactive mix of ions and electrons, reactive molecules, excited species, electric fields and to some extent also UV radiation. In the last year, this partly ionized gas has been demonstrated to have a broad antimicrobial activity, while resistance and resistance development are unlikely. Furthermore, recent research has indicated that plasmas also have a strong influence on various cell lines and cell functions, including anticancer properties. This review summarizes the major plasma designs available and their main benefits, as well as assessing possible risks of this new technology.
authors.affiliation: Department of Dermatology, Allergology and Environmental Medicine, Hospital Munich Schwabing, Koelner Platz 1, Munich 80804, Germany.
authors.forename: Georg
authors.initials: G
authors.lastname: Isbary
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Shimizu
authors.forename: Yang-Fang
authors.initials: YF
authors.lastname: Li
authors.forename: Wilhelm
authors.initials: W
authors.lastname: Stolz
authors.forename: Hubertus M
authors.initials: HM
authors.lastname: Thomas
authors.forename: Gregor E
authors.initials: GE
authors.lastname: Morfill
authors.forename: Julia L
authors.initials: JL
authors.lastname: Zimmermann
mesh_terms: D001272:Atmosphere; D004864:Equipment and Supplies / Q000009:adverse effects / Q000145:classification; D006801:Humans; D058626:Plasma Gases / Q000009:adverse effects / Q000627:therapeutic use*; D018570:Risk Assessment
chemical_list: D058626:Plasma Gases