title: Generalized alopecia with vasculitis-like changes in a dog with babesiosis.
abstract: A locally bred, 12-year-old, intact female Satsuma dog presented with generalized alopecia. Erythema, crusts and desquamation were observed primarily on the truck. Papules and erosions were present in the pinnae, and there were multiple areas of skin necrosis on the right forelimb. The cutaneous lesions had not responded to treatment with systemic antibiotics and prednisolone. The dog also had progressive anemia. Babesia gibsoni was detected in the blood, and the dog was treated with antiprotozoal agents. The skin lesions and anemia improved, but relapsed after the treatment was discontinued. Histopathological examination of skin biopsies revealed findings suggestive of early leukocytoclastic vasculitis or ischemic vasculopathy.
authors.affiliation: Laboratory of Veterinary Diagnostic Imaging, Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.
authors.forename: Yumi
authors.initials: Y
authors.lastname: Tasaki
authors.forename: Naoki
authors.initials: N
authors.lastname: Miura
authors.forename: Keita
authors.initials: K
authors.lastname: Iyori
authors.forename: Koji
authors.initials: K
authors.lastname: Nishifuji
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Endo
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Momoi
mesh_terms: D000505:Alopecia / Q000150:complications / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D000981:Antiprotozoal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001403:Babesia / Q000254:growth & development*; D001404:Babesiosis / Q000150:complications / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D001706:Biopsy / Q000662:veterinary; D004283:Dog Diseases / Q000188:drug therapy / Q000469:parasitology* / Q000473:pathology; D004285:Dogs; D005260:Female; D006651:Histocytochemistry / Q000662:veterinary; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000150:complications / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*
chemical_list: D000981:Antiprotozoal Agents