title: Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells.
abstract: Recent progress has begun to reveal the often complex and changing roles of phosphotyrosine and phosphoinositide phosphatases in regulation of immunoreceptor signaling. The resultant confusion has been further increased by discoveries of new players. Here we provide a review of recent progress in defining the roles of these enzymes in immunoreceptor-dependent mast cell, T cell and B cell activation.
authors.affiliation: Institut Pasteur, Département d'Immunologie, Centre d'Immunologie Humaine, Paris, France.
authors.forename: Yacine
authors.initials: Y
authors.lastname: Bounab
authors.forename: Andrew
authors.initials: A
authors.lastname: Getahun
authors.forename: John C
authors.initials: JC
authors.lastname: Cambier
authors.forename: Marc
authors.initials: M
authors.lastname: Daëron
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D006801:Humans; D008407:Mast Cells / Q000276:immunology*; D010744:Phosphoric Monoester Hydrolases / Q000276:immunology*; D011971:Receptors, Immunologic / Q000276:immunology*; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D011971:Receptors, Immunologic; D010744:Phosphoric Monoester Hydrolases