title: [Small compounds libraries: a research tool for chemical biology].
abstract: Obtaining and screening collections of small molecules remain a challenge for biologists. Recent advances in analytical techniques and instrumentation now make screening possible in academia. The history of the creation of such public or commercial collections and their accessibility is related. It shows that there is interest for an academic laboratory involved in medicinal chemistry, chemogenomics or "chemical biology" to organize its own collection and make it available through existing networks such as the French National chimiothèque or the European partner network "European Infrastructure of open screening platforms for Chemical Biology" EU-OpenScreen under construction.
authors.affiliation: Laboratoire de Conception, Synthèse et Vectorisation de Biomolécules (CSVB), UMR 176 CNRS-Institut Curie, Institut Curie Centre de Recherche, 75248 Paris Cedex, France. jean-claude.florent@curie.fr
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Florent
mesh_terms: D020650:Combinatorial Chemistry Techniques; D015195:Drug Design; D004353:Drug Evaluation, Preclinical; D006801:Humans; D054852:Small Molecule Libraries / Q000737:chemistry*
chemical_list: D054852:Small Molecule Libraries