title: Withdrawal of Staphylococcus aureus from intensive care units in Turkey.
abstract: BACKGROUND
  In the past, Staphylococcus aureus infections have displayed various patterns of epidemiologic curves in hospitals, particularly in intensive care units (ICUs). This study aimed to characterize the current trend in a nationwide survey of ICUs in Turkey.
  
  
  METHODS
  A total of 88 ICUs from 36 Turkish tertiary hospitals were included in this retrospective study, which was performed during the first 3 months of both 2008 (period [P] 1) and 2011 (P2). A P value ≤.01 was considered significant.
  
  
  RESULTS
  Although overall rates of hospital-acquired infection (HAI) and device-associated infection densities were similar in P1 and P2, the densities of HAIs due to S aureus and methicillin-resistant S aureus (MRSA) were significantly lower in P2 (P < .0001). However, the proportion of HAIs due to Acinetobacter was significantly higher in P2 (P < .0001).
  
  
  CONCLUSIONS
  The incidence of S aureus infections is declining rapidly in Turkish ICUs, with potential impacts on empirical treatment strategies in these ICUs.
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, GATA Haydarpasa Training Hospital, Istanbul, Turkey. Electronic address: hakanerdem1969@yahoo.com.
authors.forename: Hakan
authors.initials: H
authors.lastname: Erdem
authors.forename: Murat
authors.initials: M
authors.lastname: Dizbay
authors.forename: Selma
authors.initials: S
authors.lastname: Karabey
authors.forename: Selcuk
authors.initials: S
authors.lastname: Kaya
authors.forename: Tuna
authors.initials: T
authors.lastname: Demirdal
authors.forename: Iftihar
authors.initials: I
authors.lastname: Koksal
authors.forename: Asuman
authors.initials: A
authors.lastname: Inan
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Erayman
authors.forename: Oznur
authors.initials: O
authors.lastname: Ak
authors.forename: Aysegul
authors.initials: A
authors.lastname: Ulu-Kilic
authors.forename: Omer
authors.initials: O
authors.lastname: Karasahin
authors.forename: Ayhan
authors.initials: A
authors.lastname: Akbulut
authors.forename: Nazif
authors.initials: N
authors.lastname: Elaldi
authors.forename: Gulden
authors.initials: G
authors.lastname: Yilmaz
authors.forename: Aslihan
authors.initials: A
authors.lastname: Candevir
authors.forename: Hanefi Cem
authors.initials: HC
authors.lastname: Gul
authors.forename: Ibak
authors.initials: I
authors.lastname: Gonen
authors.forename: Oral
authors.initials: O
authors.lastname: Oncul
authors.forename: Turan
authors.initials: T
authors.lastname: Aslan
authors.forename: Emel
authors.initials: E
authors.lastname: Azak
authors.forename: Recep
authors.initials: R
authors.lastname: Tekin
authors.forename: Zeliha
authors.initials: Z
authors.lastname: Kocak Tufan
authors.forename: Ercan
authors.initials: E
authors.lastname: Yenilmez
authors.forename: Bilgin
authors.initials: B
authors.lastname: Arda
authors.forename: Gokay
authors.initials: G
authors.lastname: Gungor
authors.forename: Birsen
authors.initials: B
authors.lastname: Cetin
authors.forename: Sukran
authors.initials: S
authors.lastname: Kose
authors.forename: Hale
authors.initials: H
authors.lastname: Turan
authors.forename: Halis
authors.initials: H
authors.lastname: Akalin
authors.forename: Oguz
authors.initials: O
authors.lastname: Karabay
authors.forename: Aygul
authors.initials: A
authors.lastname: Dogan-Celik
authors.forename: Adem
authors.initials: A
authors.lastname: Albayrak
authors.forename: Tumer
authors.initials: T
authors.lastname: Guven
authors.forename: Guven
authors.initials: G
authors.lastname: Celebi
authors.forename: Nail
authors.initials: N
authors.lastname: Ozgunes
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Ersoy
authors.forename: Fatma
authors.initials: F
authors.lastname: Sirmatel
authors.forename: Nefise
authors.initials: N
authors.lastname: Oztoprak
authors.forename: Ilker Inanc
authors.initials: II
authors.lastname: Balkan
authors.forename: Fatma Nurhayat
authors.initials: FN
authors.lastname: Bayazit
authors.forename: Hasan
authors.initials: H
authors.lastname: Ucmak
authors.forename: Serkan
authors.initials: S
authors.lastname: Oncu
authors.forename: Davut
authors.initials: D
authors.lastname: Ozdemir
authors.forename: Derya
authors.initials: D
authors.lastname: Ozturk-Engin
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bitirgen
authors.forename: Fehmi
authors.initials: F
authors.lastname: Tabak
authors.forename: Filiz
authors.initials: F
authors.lastname: Akata
authors.forename: Ayşe
authors.initials: A
authors.lastname: Willke
authors.forename: Levent
authors.initials: L
authors.lastname: Gorenek
authors.forename: Salman Shaheer
authors.initials: SS
authors.lastname: Ahmed
authors.forename: Yesim
authors.initials: Y
authors.lastname: Tasova
authors.forename: Asim
authors.initials: A
authors.lastname: Ulcay
authors.forename: Saim
authors.initials: S
authors.lastname: Dayan
authors.forename: Saban
authors.initials: S
authors.lastname: Esen
authors.forename: Hakan
authors.initials: H
authors.lastname: Leblebicioglu
authors.forename: Begin
authors.initials: B
authors.lastname: Altun
authors.forename: Serhat
authors.initials: S
authors.lastname: Unal
mesh_terms: D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology*; D006801:Humans; D015994:Incidence; D007362:Intensive Care Units; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D062606:Tertiary Care Centers; D014421:Turkey / Q000453:epidemiology
keywords: Critical; Epidemiology; Incidence; Staphylococcus