title: Early hepatocellular carcinomas showing isointensity or hyperintensity in gadoxetic acid-enhanced, hepatocyte-phase magnetic resonance images.
abstract: Hypointensity in the hepatocyte phase is believed to be a key feature of hypovascular early hepatocellular carcinoma, which indicates malignancy. The 3 cases we present suggest that the converse is not true. Three small hepatocellular lesions showed isointensity/hyperintensity on gadoxetic acid-enhanced, hepatocyte-phase magnetic resonance images and were pathologically confirmed as early hepatocellular carcinomas. We conclude that isointensity or hyperintensity in the hepatocyte phase does not always represent benignity of hepatocellular lesions in the cirrhotic liver.
authors.affiliation: Department of Radiology, University of Yamanashi, Yamanashi, Japan.
authors.forename: Ningxin
authors.initials: N
authors.lastname: Chen
authors.forename: Utaroh
authors.initials: U
authors.lastname: Motosugi
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Sano
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Ichikawa
authors.forename: Masayuki
authors.initials: M
authors.lastname: Nakano
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Morisaka
authors.forename: Shintaro
authors.initials: S
authors.lastname: Ichikawa
authors.forename: Masanori
authors.initials: M
authors.lastname: Matsuda
authors.forename: Hideki
authors.initials: H
authors.lastname: Fujii
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Enomoto
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Araki
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000473:pathology; D003287:Contrast Media; D005260:Female; D022781:Hepatocytes / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male
chemical_list: D003287:Contrast Media