title: Risk of colorectal polyps in patients with sporadic gastric polyps: A case-control study.
abstract: OBJECTIVE
  To assess the risk of colonic polyps, adenomas and advanced neoplastic lesions (ANL) in patients with sporadic gastric polyps, especially those with fundic gland polyps (FGP).
  
  
  METHODS
  Clinical records of patients who had performed an upper and a lower digestive endoscopy between September 2007 and August 2008 were retrospectively analyzed. A case-control study was carried out, calling patients with gastric polyps as "cases" and patients without gastric polyps as "controls". The risk of colonic polyps, adenomas and ANL (villous component ≥ 25%, size ≥ 10 mm, or high grade dysplasia) was assessed [odds ratio (OR) and its corresponding 95%CI].
  
  
  RESULTS
  Two hundred and forty seven patients were analyzed: 78 with gastric polyps (cases) and 169 without gastric polyps (controls). Among the cases, the majority of gastric polyps were FGP (80%, CI: 69-88) and hyperplastic (20%, CI: 12-31); 25% had colonic polyps (25% hyperplastic and 68% adenomas, from which 45% were ANL). Among the controls, 20% had colonic polyps (31% hyperplastic and 63% adenomas, from which 41% were ANL). The patients with sporadic FGP had an OR of 1.56 (CI: 0.80-3.04) for colonic polyps, an OR of 1.78 (CI: 0.82-3.84) for colonic adenomas, and an OR of 0.80 (CI: 0.21-2.98) for ANL. Similar results were found in patients with gastric polyps in general.
  
  
  CONCLUSIONS
  The results of this study did not show more risk of colorectal adenomas or ANL neither in patients with sporadic gastric polyps nor in those with FGP.
authors.affiliation: Daniel Gustavo Cimmino, José Manuel Mella, Pablo Luna, Raquel González, Lisandro Pereyra, Carolina Fischer, Adriana Mohaidle, Beatriz Vizcaino, Mario Andres Medrano, Adrián Hadad, Silvia Pedreira, Luis Boerr, Digestive Endoscopy and Gastroenterology Units, Internal Medicine Department, Hospital Alemán, Buenos Aires, CP 1118, Argentina.
authors.forename: Daniel Gustavo
authors.initials: DG
authors.lastname: Cimmino
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Mella
authors.forename: Pablo
authors.initials: P
authors.lastname: Luna
authors.forename: Raquel
authors.initials: R
authors.lastname: González
authors.forename: Lisandro
authors.initials: L
authors.lastname: Pereyra
authors.forename: Carolina
authors.initials: C
authors.lastname: Fischer
authors.forename: Adriana
authors.initials: A
authors.lastname: Mohaidle
authors.forename: Beatriz
authors.initials: B
authors.lastname: Vizcaino
authors.forename: Mario Andres
authors.initials: MA
authors.lastname: Medrano
authors.forename: Adrián
authors.initials: A
authors.lastname: Hadad
authors.forename: Silvia
authors.initials: S
authors.lastname: Pedreira
authors.forename: Luis
authors.initials: L
authors.lastname: Boerr
keywords: Advanced neoplastic lesions; Case-control study; Colorectal polyps; Fundic gland polyps gastric polyps; Gastric polyps