title: Effects of neuroprotector cortexin on the dynamics of neuroendocrine system parameters in patients with organic emotionally labile (asthenic) disorders.
abstract: Addition of neuroprotector Cortexin to standard drug therapy of patients with organic emotionally labile (asthenic) disorders had a great influence on the neuroendocrine system and neurosteroid content: normalization of blood concentration of cortisol, dehydroepiandrosterone sulphate, and thyroid hormones was observed. Clinical improvement was associated with the recovery of organism homeostatic systems.
authors.affiliation: Research Institute of Menthal Health, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia. rla2003@list.ru
authors.forename: L A
authors.initials: LA
authors.lastname: Levchuk
authors.forename: S A
authors.initials: SA
authors.lastname: Ivanova
authors.forename: V Ya
authors.initials: VY
authors.lastname: Semke
mesh_terms: D000328:Adult; D000342:Affective Symptoms / Q000188:drug therapy*; D001247:Asthenia / Q000188:drug therapy*; D019314:Dehydroepiandrosterone Sulfate / Q000097:blood; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D036341:Intercellular Signaling Peptides and Proteins; D008297:Male; D019964:Mood Disorders / Q000188:drug therapy*; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D009490:Neurosecretory Systems / Q000187:drug effects; D010455:Peptides / Q000627:therapeutic use*; D013963:Thyroid Hormones / Q000097:blood; D016896:Treatment Outcome
chemical_list: D036341:Intercellular Signaling Peptides and Proteins; D018696:Neuroprotective Agents; D010455:Peptides; D013963:Thyroid Hormones; D019314:Dehydroepiandrosterone Sulfate; C056590:cortexin; D006854:Hydrocortisone