title: The expanding family of FERM proteins.
abstract: Our understanding of the FERM (4.1/ezrin/radixin/moesin) protein family has been rapidly expanding in the last few years, with the result that many new physiological functions have been ascribed to these biochemically unique proteins. In the present review, we will discuss a number of new FRMD (FERM domain)-containing proteins that were initially discovered from genome sequencing but are now being established through biochemical and genetic studies to be involved both in normal cellular processes, but are also associated with a variety of human diseases.
authors.affiliation: Medical and Biological Sciences Building, School of Medicine, University of St Andrews, St Andrews KY16 9TF, UK.
authors.forename: Susana
authors.initials: S
authors.lastname: Moleirinho
authors.forename: Andrew
authors.initials: A
authors.lastname: Tilston-Lunel
authors.forename: Liselotte
authors.initials: L
authors.lastname: Angus
authors.forename: Frank
authors.initials: F
authors.lastname: Gunn-Moore
authors.forename: Paul A
authors.initials: PA
authors.lastname: Reynolds
mesh_terms: D003598:Cytoskeletal Proteins / Q000737:chemistry* / Q000235:genetics / Q000502:physiology*; D005544:Forecasting; D006801:Humans; D008565:Membrane Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D005810:Multigene Family / Q000235:genetics; D017434:Protein Structure, Tertiary
chemical_list: D003598:Cytoskeletal Proteins; C478965:EPB41L4B protein, human; D008565:Membrane Proteins; C028841:erythrocyte membrane band 4.1 protein