title: Beyond DNA: programming and inheritance of parental methylomes.
abstract: Epigenetic reprogramming of parental genomes following fertilization is important to ensure compatibility for totipotency and development thereafter. New studies by Jiang et al. and Potok et al. now demonstrate how the parental DNA methylomes are reset in zebrafish and reveal striking differences from events in mammals.
authors.affiliation: Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK.
authors.forename: Jamie A
authors.initials: JA
authors.lastname: Hackett
authors.forename: M Azim
authors.initials: MA
authors.lastname: Surani