title: Antimicrobial activities of some mushrooms in Turkey.
abstract: BACKGROUND
  Terfezia boudieri Chatin (Pezizaceae), Agaricus brunnescens Peck (Agaricaceae) and Lactarius vellereus (Fr.) Fr. (Russulaceae) are well-known species in Turkey, and are used both for food and traditional medicine.
  
  
  OBJECTIVE
  The powdered fruit bodies of T. boudieri, A. brunnescens and L. vellereus were used to evaluate the antimicrobial activities.
  
  
  METHODS
  Chloroform, acetone and methanol extracts of T. boudieri, A. brunnescens and L. vellereus were tested for their antimicrobial activities against four Gram-positive bacteria, five Gram-negative bacteria and yeast using a micro-dilution method.
  
  
  RESULTS
  The strongest minimum inhibitory concentration (MIC) value observed against the test microorganisms was with the chloroform extract of T. boudieri (MIC 2.4 µg/mL) against Streptococcus pyogenes. Maximum antimicrobial effects were observed with the acetone extracts of T. boudieri and L. vellereus (MIC 4.8 µg/mL) against Bacillus subtilis. The strongest antifungal activity was observed with the acetone extracts of T. boudieri (MIC 2.4 µg/mL) and A. brunnescens (MIC 19.5 µg/mL) against Candida albicans. The strongest MIC values for all fungal extracts were observed between 78 and 2.4 µg/mL.
  
  
  CONCLUSIONS
  Present results demonstrated that these three mushroom species have excellent antimicrobial and antifungal activities, and thus have great potential as a source for natural health products.
authors.affiliation: Biology Department, Faculty of Science, Selcuk University, Konya, Turkey. hhuseyindogan@yahoo.com
authors.forename: Hasan Hüseyin
authors.initials: HH
authors.lastname: Doğan
authors.forename: Rüstem
authors.initials: R
authors.lastname: Duman
authors.forename: Birol
authors.initials: B
authors.lastname: Özkalp
authors.forename: Sema
authors.initials: S
authors.lastname: Aydin
mesh_terms: D000364:Agaricus / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D000935:Antifungal Agents / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D001203:Ascomycota / Q000737:chemistry*; D002176:Candida albicans / Q000187:drug effects; D048690:Fruiting Bodies, Fungal; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008519:Medicine, Traditional; D008826:Microbial Sensitivity Tests; D012997:Solvents / Q000737:chemistry; D014421:Turkey
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D012997:Solvents