title: Viral aetiology in adults with acute upper respiratory tract infection in Jinan, Northern China.
abstract: Our study investigated the epidemiology of respiratory viruses in adult patients with upper respiratory tract infection (URTI) between August 2009 and September 2010 in Jinan, northern China. Nasal and throat swabs (n = 596) were collected from adult patients with URTIs. Nine respiratory-related viruses, including IFV, PIV, HRV, HMPV, HBoV, HCoV, ADV, RSV, and EV, were detected in all samples by conventional and reverse transcription polymerase chain reactions. Positive detection rate for respiratory virus was 38.76% and codetection rate was 4.70% in adults with acute respiratory tract infections. IFV (20.81%) was the dominant agent detected and IFVB had a higher incidence (12.58%) than IFVA (7.72%). Detection rates of 8.22%, 5.03%, 3.69%, and 2.52% were observed for HBoV, HRV, EV, and RSV, respectively. HCoV had the lowest detection rate of 0.50%. HBoV, HRV, EV, and ADV infection rates were higher in the 14-25-year-old group than in the 26-65-year-old group. Codetection rates were higher (7.52%) in the 14-25-year-old group than in the older age group (2.64%). The spectrum of respiratory virus infection in adult patients with URTIs was different in Jinan compared with other cities in China.
authors.affiliation: Shandong Medicinal Biotechnology Centre, Key Laboratory for Modern Medicine and Technology of Shandong Province, Key Laboratory for Virology of Shandong Province, Key Laboratory for Biotech-Drugs, Ministry of Health, Shandong Academy of Medical Sciences, Jinan 250062, China.
authors.forename: Yanqin
authors.initials: Y
authors.lastname: Lu
authors.forename: Jiabei
authors.initials: J
authors.lastname: Tong
authors.forename: Fengyan
authors.initials: F
authors.lastname: Pei
authors.forename: Yanping
authors.initials: Y
authors.lastname: Yang
authors.forename: Dong
authors.initials: D
authors.lastname: Xu
authors.forename: Mingyu
authors.initials: M
authors.lastname: Ji
authors.forename: Chunyan
authors.initials: C
authors.lastname: Xing
authors.forename: Pingdong
authors.initials: P
authors.lastname: Jia
authors.forename: Chao
authors.initials: C
authors.lastname: Xu
authors.forename: Yunshan
authors.initials: Y
authors.lastname: Wang
authors.forename: Gongchao
authors.initials: G
authors.lastname: Li
authors.forename: Zhenbin
authors.initials: Z
authors.lastname: Chai
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Jinxiang
authors.initials: J
authors.lastname: Han
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China / Q000453:epidemiology; D015897:Comorbidity; D005260:Female; D056661:Human bocavirus / Q000302:isolation & purification; D006801:Humans; D007251:Influenza, Human / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D008297:Male; D008875:Middle Aged; D009975:Orthomyxoviridae / Q000302:isolation & purification; D010322:Parvoviridae Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D010850:Picornaviridae Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D015995:Prevalence; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D012136:Respiratory Syncytial Viruses / Q000302:isolation & purification; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D012229:Rhinovirus / Q000302:isolation & purification