title: A rare der(Y)t(Y;1)(q12;q12) in a patient with post-polycythemic myelofibrosis: a case report.
abstract: We describe a case of post-polycythemic myelofibrosis harboring der(Y)t(Y;1)(q12;q12). The patient was a 69-year-old man and was initially diagnosed with polycythemia vera. During the clinical course of his condition, the polycythemia developed into myelofibrosis. Chromosome analysis detected der(Y)t(Y;1)(q12;q12). We discuss the association between der(Y)t(Y;1)(q11~12;q12~21) and tumorigenesis along with a review of literature.
authors.affiliation: Department of Hematology, Seichokai Fuchu Hospital 1-10-17 Hiko-cho, Izumi, Osaka 594-0076, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Manabe
authors.forename: Osami
authors.initials: O
authors.lastname: Takeda
authors.forename: Junya
authors.initials: J
authors.lastname: Okita
authors.forename: Teruhito
authors.initials: T
authors.lastname: Takakuwa
authors.forename: Naonori
authors.initials: N
authors.lastname: Harada
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Nakano
authors.forename: Shuichiro
authors.initials: S
authors.lastname: Okamoto
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Aoyama
authors.forename: Takeo
authors.initials: T
authors.lastname: Kumura
authors.forename: Tadanobu
authors.initials: T
authors.lastname: Ohta
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Furukawa
authors.forename: Atsuko
authors.initials: A
authors.lastname: Mugitani
keywords: Post-polycythemic myelofibrosis; chromosomal abnormality; der(Y)t(Y;1)(q12;q12)