title: A rare case of rosai-dorfman disease in an adult male associated with auto-immune hemolytic anemia.
abstract: Rosai-Dorfman disease (RDD) is a rare benign histiocytic proliferative disorder predominantly of the lymph nodes, which mostly occurs in children and young adults typically presenting with lymphadenopathy. Our case is of a 63 year-old African-American male who presented with subjective fever, weight loss, bilateral axillary and inguinal lymphadenopathy as well as auto-immune hemolytic anemia. The histological analysis showed emperipolesis and histiocytes that were positive for S-100 and CD-68 consistent with RDD. After steroid treatment and splenectomy, patient's symptoms and hemolytic anemia had resolved. Our case is the first case of RDD reported to be associated with auto-immune hemolytic anemia in an adult.
authors.affiliation: Internal Medicine, University of California, San Francisco-Fresno, Fresno, California.
authors.forename: Mickey
authors.initials: M
authors.lastname: Sachdeva
authors.forename: Haifaa
authors.initials: H
authors.lastname: Abdulhaq