title: Therapeutic effects of glycyrrhizic acid.
abstract: Glycyrrhizic acid (GA), belonging to a class of triterpenes, is a conjugate of two molecules, namely glucuronic acid and glycyrrhetinic acid. It is naturally extracted from the roots of licorice plants. With its more common uses in the confectionery and cosmetics industry, GA extends its applications as a herbal medicine for a wide range of ailments. At low appropriate doses, anti-inflammatory, anti-diabetic, antioxidant, anti-tumor, antimicrobial and anti-viral properties have been reported by researchers worldwide. This review summarizes the effects of GA on metabolic syndrome, tumorigenesis, microbes and viruses, oxidative stress, and inflammation, as well as the reported side effects of the drug.
authors.affiliation: School of Biosciences, Taylor's University, Lakeside Campus, Selangor, Malaysia. jm5223lee@gmail.com
authors.forename: Lee Jia
authors.initials: LJ
authors.lastname: Ming
authors.forename: Adeline Chia Yoke
authors.initials: AC
authors.lastname: Yin
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D050034:Antidiuretic Agents / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D000975:Antioxidants / Q000627:therapeutic use; D019695:Glycyrrhizic Acid / Q000627:therapeutic use*; D006801:Humans
chemical_list: D000893:Anti-Inflammatory Agents; D050034:Antidiuretic Agents; D000970:Antineoplastic Agents; D000975:Antioxidants; D019695:Glycyrrhizic Acid