title: Bacteremia due to imipenem-resistant Roseomonas mucosa in a child with acute lymphoblastic leukemia.
abstract: Roseomonas are described as opportunistic pathogens rarely involved in human infections. Their identification requires molecular methods and their antimicrobial susceptibility pattern varies according to the species. We report the first case of bacteremia due to Roseomonas mucosa in a child with leukemia and reviewed pediatric cases of Roseomonas infection, for which undoubted strain identification was available. Favorable outcome was observed despite resistance to numerous β-lactams that may account for delayed effective treatment, suggesting the low virulence of Roseomonas in children. Here, the strain also displayed unusual resistance to imipenem, highlighting the possible acquisition of additional resistance by this pathogen.
authors.affiliation: *Unité de Bactériologie Siméon de Buochberg, UMR 5119 ECOSYM, Equipe Pathogènes et Environnements, U.F.R. des Sciences Pharmaceutiques et Biologiques, Université Montpellier 1 ‡Département de Pédiatrie, Unité d'onco-hématologie †Laboratoire de Bactériologie, Hôpital Arnaud de Villeneuve §Laboratoire d'Hygiène hospitalière, Centre Hospitalier Régional Universitaire de Montpellier, Montpellier, France.
authors.forename: Anne-Laure
authors.initials: AL
authors.lastname: Michon
authors.forename: Laure
authors.initials: L
authors.lastname: Saumet
authors.forename: Alice
authors.initials: A
authors.lastname: Bourdier
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Haouy
authors.forename: Nicolas
authors.initials: N
authors.lastname: Sirvent
authors.forename: Hélène
authors.initials: H
authors.lastname: Marchandin
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D002648:Child; D024881:Drug Resistance, Bacterial; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use*; D042082:Methylobacteriaceae / Q000187:drug effects / Q000302:isolation & purification*; D009092:Mucous Membrane / Q000382:microbiology*; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D011379:Prognosis
chemical_list: D000900:Anti-Bacterial Agents; D015378:Imipenem