title: Synthesis of benzidine derivatives via FeCl3·6H2O-promoted oxidative coupling of anilines.
abstract: Under open-flask conditions in the presence of commercially available FeCl3·6H2O, N,N-disubstituted anilines can be converted into diversely functionalized benzidines with yields of up to 99%. Oxidative coupling was extended to N-monosubstituted anilines, and the method was applied to the efficient preparation of 6,6'-biquinoline. Mechanistic investigations have also been performed to explain the observed reactivities.
authors.affiliation: School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400044, China.
authors.forename: Xuege
authors.initials: X
authors.lastname: Ling
authors.forename: Yan
authors.initials: Y
authors.lastname: Xiong
authors.forename: Ruofeng
authors.initials: R
authors.lastname: Huang
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Zhang
authors.forename: Shuting
authors.initials: S
authors.lastname: Zhang
authors.forename: Changguo
authors.initials: C
authors.lastname: Chen
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D001560:Benzidines / Q000138:chemical synthesis* / Q000737:chemistry; D002712:Chlorides / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000814:Aniline Compounds; D001560:Benzidines; D002712:Chlorides; D005290:Ferric Compounds; C029876:benzidine; C023650:aniline; C024555:ferric chloride