title: [Indications for medical treatment of acute appendicitis].
abstract: The acute appendicitis (AA) is an infection of the vermiform appendix and conservative antibiotic treatment is regularly mentioned since 50 years. Its success depends on the susceptibility of bacteria to empiric antibiotic therapy. The main bias of the studies comparing conservative antibiotic treatment versus appendectomy is that AA can not be proven histologically during medical treatment. However, after antibiotic conservative, 12-23% of patients are operated early after revaluation, and 11 to 15% in the first year for a total of 25% to 40% failure of conservative antibiotic treatment when proposed in first intention. In case of complicated appendicitis, severe infection and peritonitis, surgical treatment should be carried out urgently and remains the gold standard.
authors.affiliation: Université Paris-Descartes, service de chirurgie digestive, unité mobile de microbiologie clinique, Hôpital européen Georges-Pompidou, AP-HP, 75015 Paris, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Geri
authors.forename: Thibaut
authors.initials: T
authors.lastname: Charrier
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Mainardi
authors.forename: Franck
authors.initials: F
authors.lastname: Zinzindohoué
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001064:Appendicitis / Q000188:drug therapy*; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents