title: Functions of the hemodynamic response during hypercapnia. Functional MRI study.
abstract: Functional MRI was applied for studying the dynamics of brain hemodynamic response evoked by involuntary (visual) and voluntary (motor) excitations under condition of interdependent sensorimotor and visual paradigm (hand clenching in response to a light flash). Activation of the corresponding areas of the visual and sensorimotor cortex (Brodmann areas 18-4, respectively) was observed and quantitative data characterizing the response signal maximum delay were obtained. It was found that breath holding-induced hypercapnia disorders neuronal networks created during visual-motor stimulation.
authors.affiliation: International Tomography Center, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia. as@tomo.nsc.ru
authors.forename: A A
authors.initials: AA
authors.lastname: Savelov
authors.forename: E D
authors.initials: ED
authors.lastname: Petrovskii
authors.forename: E S
authors.initials: ES
authors.lastname: Karamamed-Ogly
authors.forename: M B
authors.initials: MB
authors.lastname: Shtark
mesh_terms: D000328:Adult; D001921:Brain / Q000098:blood supply*; D001931:Brain Mapping; D062485:Breath Holding; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D006935:Hypercapnia / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009043:Motor Activity / Q000502:physiology; D009044:Motor Cortex / Q000502:physiology*; D010775:Photic Stimulation; D014793:Visual Cortex / Q000502:physiology*; D055815:Young Adult