title: [Management of prostate cancer in the elderly].
abstract: The management of prostate cancer in elderly patients is a topic of controversial discussion. The current guidelines recommend diagnosis and treatment of prostate cancer only in patients with a life expectancy of more than 10 years. Especially in elderly patients pre-existing comorbidities play a crucial role in life expectancy. In clinical practice mostly patient age alone is considered for the treatment decision; however, a guideline-based therapy of prostate cancer should also be offered to elderly patients. The treatment decision should be based on patient general health status and the oncological risk. The patient individual health status can be determined on the basis of comorbidities present and patient nutritional and performance status. For an optimal therapy regime the oncological risk has to be considered in treatment decisions. The aim of this article is to give an overview of risk stratification and treatment options for localized and metastatic prostate cancer in elderly patients.
authors.affiliation: Klinik für Urologie und Kinderurologie, Urologische Universitätsklinik Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Deutschland. gencay.hatiboglu@med.uni-heidelberg.de
authors.forename: G
authors.initials: G
authors.lastname: Hatiboglu
authors.forename: B
authors.initials: B
authors.lastname: Hadaschik
authors.forename: D
authors.initials: D
authors.lastname: Teber
authors.forename: S
authors.initials: S
authors.lastname: Duensing
authors.forename: M
authors.initials: M
authors.lastname: Hohenfellner
authors.forename: S
authors.initials: S
authors.lastname: Pahernik
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D015577:Geriatric Assessment / Q000379:methods*; D006299:Health Services for the Aged / Q000458:organization & administration*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010347:Patient Care Planning / Q000458:organization & administration*; D011379:Prognosis; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D018570:Risk Assessment
chemical_list: D000970:Antineoplastic Agents