title: Intracerebral schwannomas: a rare disease with varying natural history.
abstract: Although intracerebral schwannomas are typically regarded as benign intracranial tumors, malignancy and recurrence have been reported among patients harboring such neoplasms. The available literature consists of case reports and small series that present variable characteristics distinguishing these unusual lesions. Little advancement has been made to further the understanding and management of these tumors. The authors present 3 cases from their institution that highlight the difference between typical benign intracerebral schwannomas and histopathological variants that may portend more aggressive behavior. Also provided is a review of the literature in the hope of gaining a better understanding of these rare tumors.
authors.affiliation: Department of Neurosurgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8855, USA. william_w_scott@hotmail.com
authors.forename: William W
authors.initials: WW
authors.lastname: Scott
authors.forename: Korgun
authors.initials: K
authors.lastname: Koral
authors.forename: Linda R
authors.initials: LR
authors.lastname: Margraf
authors.forename: Laura
authors.initials: L
authors.lastname: Klesse
authors.forename: David J
authors.initials: DJ
authors.lastname: Sacco
authors.forename: Bradley E
authors.initials: BE
authors.lastname: Weprin
mesh_terms: D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D002648:Child; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D009442:Neurilemmoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D059906:Neuroimaging / Q000379:methods; D035583:Rare Diseases / Q000473:pathology / Q000601:surgery; D012086:Reoperation; D012189:Retrospective Studies; D012640:Seizures / Q000209:etiology; D016896:Treatment Outcome