title: Did cholera toxin finally get caught?
abstract: To orchestrate immune responses, pathogen-recognition receptors have evolved sophisticated strategies to monitor pathogenic processes. In this issue of Cell Host & Microbe, a study by Cho et al. reveals a mechanism of immune recognition that relies on the sensing of cholera toxin within the endoplasmic reticulum.
authors.affiliation: Department of Biochemistry, University of Lausanne, 155 Chemin Des Boveresses, 1066 Epalinges, Switzerland. Electronic address: fabio.martinon@unil.ch.
authors.forename: Fabio
authors.initials: F
authors.lastname: Martinon
authors.affiliation: Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 19, 1015 Lausanne, Switzerland. Electronic address: gisou.vandergoot@epfl.ch.
authors.forename: F Gisou
authors.initials: FG
authors.lastname: van der Goot
mesh_terms: D002772:Cholera Toxin / Q000276:immunology* / Q000378:metabolism*; D000071457:DEAD Box Protein 58; D053487:DEAD-box RNA Helicases / Q000276:immunology*; D004722:Endoribonucleases / Q000276:immunology* / Q000378:metabolism*; D006801:Humans; D007113:Immunity, Innate; D017346:Protein Serine-Threonine Kinases / Q000276:immunology* / Q000378:metabolism*; D011971:Receptors, Immunologic; D015398:Signal Transduction
chemical_list: D011971:Receptors, Immunologic; D002772:Cholera Toxin; C528229:ERN1 protein, human; D017346:Protein Serine-Threonine Kinases; D004722:Endoribonucleases; C452820:RIGI protein, human; D000071457:DEAD Box Protein 58; D053487:DEAD-box RNA Helicases