title: Turn-on selective vitamin B6 derivative fluorescent probe for histidine detection in biological samples.
abstract: A new compound L soluble in water derived from vitamin B6 was successfully synthesized and characterized. The complex LAl(3+) is a turn-on selective fluorescent probe for histidine in HEPES buffer, with detection and quantification limits of 0.3 μM and 0.6 μM, respectively. The application of the complex LAl(3+) in real urine samples is reported.
authors.affiliation: BIOSCOPE group, REQUIMTE-CQFB, Chemistry Department, Faculty of Science and Technology, University NOVA of Lisbon, 2829-516, Monte de Caparica, Portugal. ejo14209@fct.unl.pt
authors.forename: Elisabete
authors.initials: E
authors.lastname: Oliveira
authors.forename: Carla
authors.initials: C
authors.lastname: Santos
authors.forename: Patrícia
authors.initials: P
authors.lastname: Poeta
authors.forename: José Luis
authors.initials: JL
authors.lastname: Capelo
authors.forename: Carlos
authors.initials: C
authors.lastname: Lodeiro
mesh_terms: D005260:Female; D005456:Fluorescent Dyes / Q000737:chemistry*; D006639:Histidine / Q000652:urine*; D006801:Humans; D057230:Limit of Detection; D008297:Male; D008670:Metals / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D016482:Urinalysis / Q000379:methods*; D025101:Vitamin B 6 / Q000031:analogs & derivatives*
chemical_list: D005456:Fluorescent Dyes; D008670:Metals; D006639:Histidine; D025101:Vitamin B 6