title: Prognosis of dialysed patients after kidney transplant failure.
abstract: OBJECTIVE
  Patients with a failed kidney transplant represent a unique, high-risk chronic kidney disease population that is increasing in number, and may be sub-optimally managed. Our aim was to compare the survival of patients with failed allografts to patients with native kidney failure and to assess whether their survival is affected by the graft resection.
  
  
  METHODS
  Kaplan-Meier and Cox-regression survival analyses were performed on the data of 57 patients with graft failure and of 123 transplant-naive haemodialysed patients.
  
  
  RESULTS
  After adjustment for age and gender, there was no statistically significant difference in the mortality of patients in the two groups. The 43 patients, who had a transplanted kidney nephrectomy had a statistically not significant survival benefit over non-nephrectomised patients (age and gender adjusted hazard ratio: 0.56 95 % confidence interval: 0.24-1.58, p-value: 0.18).
  
  
  CONCLUSIONS
  Elective graft resection is a safe, effective alternative for both the treatment and the prevention of the chronic inflammatory state associated with a failed kidney transplant.
authors.affiliation: 1st Department of Internal Medicine, Division of Nephrology, Faculty of Medicine, Medical & Health Science Centre, University of Debrecen, 4012, Debrecen, Nagyerdei krt. 98., Hungary.
authors.forename: Réka P
authors.initials: RP
authors.lastname: Szabó
authors.forename: Nóra
authors.initials: N
authors.lastname: Klenk
authors.forename: József
authors.initials: J
authors.lastname: Balla
authors.forename: László
authors.initials: L
authors.lastname: Asztalos
authors.forename: László
authors.initials: L
authors.lastname: Szabó
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Vokó
mesh_terms: D000328:Adult; D000367:Age Factors; D016001:Confidence Intervals; D005260:Female; D006084:Graft Rejection / Q000401:mortality / Q000601:surgery; D006085:Graft Survival; D006801:Humans; D053208:Kaplan-Meier Estimate; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D011379:Prognosis; D016016:Proportional Hazards Models; D006435:Renal Dialysis; D012086:Reoperation; D012189:Retrospective Studies; D012737:Sex Factors; D016019:Survival Analysis; D017211:Treatment Failure