title: The oral commensal microbiota bites back through Nod1.
abstract: The mechanisms through which commensal bacterial populations cause inflammatory disease when shifted to dysbiotic community structures are poorly understood. Jiao et al. (2013) demonstrate that, in the case of inflammatory disease in the mouth, stimulation of the intracellular pattern recognition receptor Nod1 is a critical determinant.
authors.affiliation: Blizard Institute, Barts and The London School of Medicine, Queen Mary University of London, London E1 2AT, UK. Electronic address: m.a.curtis@qmul.ac.uk.
authors.forename: Mike
authors.initials: M
authors.lastname: Curtis
mesh_terms: D016301:Alveolar Bone Loss / Q000473:pathology*; D000818:Animals; D001419:Bacteria / Q000472:pathogenicity*; D054884:Host-Pathogen Interactions; D009055:Mouth / Q000382:microbiology*; D053474:Nod1 Signaling Adaptor Protein / Q000378:metabolism*; D010518:Periodontitis / Q000473:pathology*; D015398:Signal Transduction
chemical_list: D053474:Nod1 Signaling Adaptor Protein; C507873:Nod1 protein, mouse