title: Nutraceutical properties and polyphenolic profile of berry skin and wine of Vitis vinifera L. (cv. Aglianico).
abstract: Red grapes are rich in phenolics, flavonoids, anthocyanins and resveratrol, all substances which have been suggested as having nutraceutical and health benefits. The berry skin and wine of grape cultivar Vitis vinifera L. (cv. Aglianico), grown in Basilicata (Southern Italy) were examined to determinate the presence of the above mentioned compounds as well as to establish the inorganic cation profile. HPLC analysis coupled with LC-ESI/MS/MS detected high contents of total flavonols and anthocyanins in berry skin and wine. The wine made with the same grape used for berry skin assays showed a notable presence of quercetin-3-O-glucoside (39.4% of total flavonols), and malvidin and petunidin derivatives (63.9% and 10.8% of total anthocyanins, respectively). The strong antioxidant ROS-scavenging activity, determined by both DPPH and FRAP assays, and the high resveratrol content confer high sensory characteristics resulted to be associated with positive nutraceutical properties of these grapes and wine. The level of cis-resveratrol was lower than trans-resveratrol in both berry skin and wine reaching 44.1mg/kg and 0.3mg/l, respectively. The cation profile presents low levels of Ca, Cu, K, Fe, Zn and Cd compared to numerous, important red wines, such as Monastrell and Tempranillo.
authors.affiliation: Pharmaco-Chemical Department, Faculty of Pharmacy, University of Messina, Viale Annunziata, I-98168 Messina, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: De Nisco
authors.forename: Michele
authors.initials: M
authors.lastname: Manfra
authors.forename: Adele
authors.initials: A
authors.lastname: Bolognese
authors.forename: Adriano
authors.initials: A
authors.lastname: Sofo
authors.forename: Antonio
authors.initials: A
authors.lastname: Scopa
authors.forename: Gian Carlo
authors.initials: GC
authors.lastname: Tenore
authors.forename: Francesco
authors.initials: F
authors.lastname: Pagano
authors.forename: Ciro
authors.initials: C
authors.lastname: Milite
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Russo
mesh_terms: D000975:Antioxidants / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D019587:Dietary Supplements / Q000032:analysis*; D005638:Fruit / Q000737:chemistry*; D010636:Phenols / Q000032:analysis*; D027843:Vitis / Q000737:chemistry*; D014920:Wine / Q000032:analysis*
chemical_list: D000975:Antioxidants; D010636:Phenols