title: Adenocarcinoma of the colon in children: case series and mini-review of the literature.
abstract: Colon cancer is extremely rare in children. This article reports three cases of adenocarcinoma of the colon. A 12-year-old boy, a 13-year-old boy, and a 13-year-old girl presented with constipation and abdominal enlargement over a two-month duration. Abdominal ultrasound and barium enema confirmed a stenotic segment at the rectum with obvious shouldering. Adenocarcinoma was diagnosed following colonoscopic biopsy and laparotomy. We conclude that any child presenting with unexplained persistent constipation, abdominal distension or bleeding per rectum, colon cancer should be suspected and investigated with endoscopy or barium enema.
authors.affiliation: Hematology/Oncology Unit, Mansoura University Children Hospital, Mansoura, Egypt. ytonbary@gmail.com
authors.forename: Youssef
authors.initials: Y
authors.lastname: Al-Tonbary
authors.forename: Ahmad
authors.initials: A
authors.lastname: Darwish
authors.forename: Ahmad
authors.initials: A
authors.lastname: El-Hussein
authors.forename: Ashraf
authors.initials: A
authors.lastname: Fouda
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D000230:Adenocarcinoma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001466:Barium Sulfate; D002648:Child; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use; D006470:Hemorrhage; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008297:Male; D009367:Neoplasm Staging; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D009944:Organoplatinum Compounds; D001466:Barium Sulfate; D002955:Leucovorin; D005472:Fluorouracil