title: Ln[N(SiMe3)2]3-catalyzed cycloaddition of terminal alkynes to azides leading to 1,5-disubstituted 1,2,3-triazoles: new mechanistic features.
abstract: The first example of rare earth metal-catalyzed cycloaddition of terminal alkynes to azides resulting in the formation of 1,5-disubstituted 1,2,3-triazoles is described. Preliminary studies revealed that the present cycloaddition shows unprecedented mechanistic features involving a tandem anionic cascade cyclization and anti-addition across the C≡C triple bond.
authors.affiliation: Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200433, People's Republic of China.
authors.forename: Longcheng
authors.initials: L
authors.lastname: Hong
authors.forename: Weijia
authors.initials: W
authors.lastname: Lin
authors.forename: Fangjun
authors.initials: F
authors.lastname: Zhang
authors.forename: Ruiting
authors.initials: R
authors.lastname: Liu
authors.forename: Xigeng
authors.initials: X
authors.lastname: Zhou
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D001386:Azides; D028581:Lanthanoid Series Elements; D009942:Organometallic Compounds; D014230:Triazoles