title: Four new citrinin derivatives from a marine-derived Penicillium sp. fungal strain.
abstract: Four new citrinin derivatives, including two citrinin dimers and two citrinin monomer derivatives, were isolated and identified from a marine-derived fungal strain Penicillium sp. ML226 along with six known related compounds. Their structures were elucidated by spectroscopic and chemical methods. The new compounds showed modest cytotoxic activity against HepG-2 cell line and weak antimicrobial activity against Staphylococcus aureus.
authors.affiliation: School of Life Sciences, Xiamen University, 422 South Siming Road, Xiamen, Fujian 361005, China.
authors.forename: Mei Ling
authors.initials: ML
authors.lastname: Wang
authors.forename: Chun Hua
authors.initials: CH
authors.lastname: Lu
authors.forename: Qing Yan
authors.initials: QY
authors.lastname: Xu
authors.forename: Si Yang
authors.initials: SY
authors.lastname: Song
authors.forename: Zhi Yu
authors.initials: ZY
authors.lastname: Hu
authors.forename: Zhong Hui
authors.initials: ZH
authors.lastname: Zheng
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D059001:Aquatic Organisms / Q000737:chemistry*; D002953:Citrinin / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D003603:Cytotoxins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D056945:Hep G2 Cells; D006801:Humans; D015394:Molecular Structure; D010407:Penicillium / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000254:growth & development*
chemical_list: D000900:Anti-Bacterial Agents; D003603:Cytotoxins; D002953:Citrinin