title: Lipid emulsion therapy in cardiodepressive syndrome after diltiazem overdose--case report.
abstract: We present a case of diltiazem overdose in which the patient ingested 5.6 g in an apparent suicide attempt. She was admitted in the emergency department 2 hours postingestion with cardiodepressive syndrome. She was treated with gastric lavage, activated charcoal, intravenous fluids, calcium, and epinephrine, without improvement in vital signs. We gave her an infusion of 20% intralipid, leading to a favorable evolution. The patient was stable hemodynamically and metabolic in the following 24 hours. She was alert and oriented and was extubated in the second day. She was discharged after 4 days in a good state and without any neurologic deficits.
authors.affiliation: Internal Medicine Department, II Internal Medical Clinic, Sf. Spiridon Clinical Emergency Hospital, Gr.T.Popa University of Medicine and Pharmacy, Iasi, Romania. crisbologa@yahoo.com
authors.forename: Cristina
authors.initials: C
authors.lastname: Bologa
authors.forename: Catalina
authors.initials: C
authors.lastname: Lionte
authors.forename: Adorata
authors.initials: A
authors.lastname: Coman
authors.forename: Laurentiu
authors.initials: L
authors.lastname: Sorodoc
mesh_terms: D000369:Aged, 80 and over; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000628:therapy*; D002121:Calcium Channel Blockers / Q000506:poisoning*; D004110:Diltiazem / Q000506:poisoning*; D062787:Drug Overdose / Q000150:complications*; D005217:Fat Emulsions, Intravenous / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D013406:Suicide, Attempted; D013577:Syndrome
chemical_list: D002121:Calcium Channel Blockers; D005217:Fat Emulsions, Intravenous; D004110:Diltiazem