title: Identification of recombination in the envelope gene of simian foamy virus serotype 2 isolated from Macaca cyclopis.
abstract: The full-length sequence of simian foamy virus serotype 2 (SFVmcy-2), isolated from a Taiwanese macaque, was determined. SFVmcy-2 was highly related to SFV serotype 1 (SFVmcy-1), an isolate from the same species, except in the putative receptor binding domain (RBD) in env, which contained novel sequences related to SFV serotype 3 (SFVagm-3), isolated from an African green monkey. The results identify a potential region of neutralization in SFVs and demonstrate recombination between genetically divergent foamy viruses.
authors.affiliation: Laboratory of Retroviruses, Division of Viral Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Bethesda, Maryland, USA.
authors.forename: Teresa A
authors.initials: TA
authors.lastname: Galvin
authors.forename: Imran A
authors.initials: IA
authors.lastname: Ahmed
authors.forename: Muhammad
authors.initials: M
authors.lastname: Shahabuddin
authors.forename: Theodore
authors.initials: T
authors.lastname: Bryan
authors.forename: Arifa S
authors.initials: AS
authors.lastname: Khan
mesh_terms: D000818:Animals; D016000:Cluster Analysis; D015686:Gene Products, env / Q000235:genetics*; D008251:Macaca; D008969:Molecular Sequence Data; D010802:Phylogeny; D018419:Primate Diseases / Q000821:virology*; D012367:RNA, Viral / Q000235:genetics; D011995:Recombination, Genetic; D012192:Retroviridae Infections / Q000662:veterinary* / Q000821:virology; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D053150:Simian foamy virus / Q000235:genetics* / Q000302:isolation & purification; D013624:Taiwan
chemical_list: D015686:Gene Products, env; D012367:RNA, Viral