title: Associations of moderate to severe asthma with obstructive sleep apnea.
abstract: OBJECTIVE
  This study aimed to evaluate the correlation between associating factors of moderate to severe asthma with obstructive sleep apnea (OSA).
  
  
  METHODS
  One hundred and sixty-seven patients who visited the pulmonary and sleep clinic in Severance Hospital presenting with symptoms of sleep-disordered breathing were evaluated. All subjects were screened with ApneaLink. Thirty-two subjects with a high likelihood of having OSA were assessed with full polysomnography (PSG).
  
  
  RESULTS
  The mean age was 58.8±12.0 years and 58.7% of subjects were male. The mean ApneaLink apnea-hypopnea index (AHI) was 12.7±13.0/hr. The mean ApneaLink AHI for the 32 selected high risk patients of OSA was 22.3±13.2/hr, which was lower than the sleep laboratory-based PSG AHI of 39.1±20.5/hr. When OSA was defined at an ApneaLink AHI≥5/hr, the positive correlating factors for OSA were age, male gender, and moderate to severe asthma.
  
  
  CONCLUSIONS
  Moderate to severe asthma showed strong correlation with OSA when defined at an ApneaLink AHI≥5/hr.
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Korea.
authors.forename: Min Kwang
authors.initials: MK
authors.lastname: Byun
authors.forename: Seon Cheol
authors.initials: SC
authors.lastname: Park
authors.forename: Yoon Soo
authors.initials: YS
authors.lastname: Chang
authors.forename: Young Sam
authors.initials: YS
authors.lastname: Kim
authors.forename: Se Kyu
authors.initials: SK
authors.lastname: Kim
authors.forename: Hyung Jung
authors.initials: HJ
authors.lastname: Kim
authors.forename: Joon
authors.initials: J
authors.lastname: Chang
authors.forename: Chul Min
authors.initials: CM
authors.lastname: Ahn
authors.forename: Moo Suk
authors.initials: MS
authors.lastname: Park
mesh_terms: D000368:Aged; D001249:Asthma / Q000150:complications / Q000453:epidemiology / Q000209:etiology*; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography / Q000295:instrumentation; D012720:Severity of Illness Index; D012891:Sleep Apnea Syndromes / Q000453:epidemiology / Q000209:etiology; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology*
keywords: Apnea-hypopnea index; ApneaLink; asthma; obstructive sleep apnea; sleep-disordered breathing