title: Unilateral proptosis: an unusual presentation of prostatic carcinoma.
abstract: A 68-year-old man presented acutely with periorbital pain and proptosis of the right eye, on a background of generalised pain and weight loss. Imaging showed bilateral signal abnormalities in the basal skull extending into the extraconal orbits with compression of the right optic nerve. His medical history revealed symptoms in keeping with benign prostatic hypertrophy. However, the prostate was irregular on rectal examination and prostate-specific antigen was markedly raised at 1880 ng/dl. A provisional diagnosis of metastatic prostatic carcinoma was made based on the clinical and radiological picture. This was later confirmed to be metastatic adenocarcinoma through means of tissue diagnosis.
authors.affiliation: Oxford University, Oxford, UK.
authors.forename: Anna Louise
authors.initials: AL
authors.lastname: Pouncey
authors.forename: Thomas Peter
authors.initials: TP
authors.lastname: Fox
authors.forename: Catherine Anne
authors.initials: CA
authors.lastname: Bryant
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005094:Exophthalmos / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D011471:Prostatic Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014792:Visual Acuity