title: Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides.
abstract: We describe a photonic waveguide where FRET is routed uni-directionally along a double-stranded DNA track. The efficiency of FRET is modulated by the supramolecular control of fluorophores along double-stranded DNA using fluorophore-tethered Pyrrole-Imidazole polyamides (PAs). We show that uni-directional FRET is enhanced by the complete assembly of each of the constituent parts, resulting in the selective routing of light along simple DNA duplexes as well as a three-way junction (3WJ).
authors.affiliation: Center for Nanomedicine and Nanobiotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, Guangdong, PR China.
authors.forename: Wu
authors.initials: W
authors.lastname: Su
authors.forename: Clive R
authors.initials: CR
authors.lastname: Bagshaw
authors.forename: Glenn A
authors.initials: GA
authors.lastname: Burley
mesh_terms: D004247:DNA / Q000737:chemistry*; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes; D007093:Imidazoles / Q000737:chemistry*; D009757:Nylons / Q000737:chemistry*; D055095:Optics and Photonics; D011758:Pyrroles / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D007093:Imidazoles; D009757:Nylons; D011758:Pyrroles; C029899:imidazole; D004247:DNA