title: [Vacuum therapy for erectile dysfunction that fails to respond to PDE-5i: report of 70 cases].
abstract: OBJECTIVE
  To assess the efficacy and safety of the Osbon ErecAid Vacuum Therapy System in the treatment of erectile dysfunction (ED) that fails to respond to PDE-5i.
  
  
  METHODS
  This study included 70 cases of ED not responding to the medication of PDE-5i. The patients were aged 25 -66 (38.9 +/- 9.1) years. Under our direction, the patients used the Osbon ErecAid Vacuum Therapy System for a month to increase blood oxygenation to the corpora cavernosa, and then employed the vacuum constriction device (VCD) to maintain penile erection for sexual intercourse. We compared their IIEF-5 scores and their and their partners' sexual satisfaction before and 3 months after treatment, and evaluated the safety and effect of the vacuum therapy.
  
  
  RESULTS
  The mean IIEF-5 scores of the patients were significantly increased from 10.2 +/- 4.0 before treatment to 13.3 +/- 4.7 at 3 months after the vacuum therapy (P < 0.05). The rate of therapeutic effectiveness was 77.1% (54/70), and the rates of sexual satisfaction of the patients and their partners were 64.3% (45/70) and 65.7% (46/70),
  
  
  CONCLUSIONS
  Vacuum therapy for ED that does not respond to PDE-5i can significantly improve the patients' erectile function as well as their and their partners'sexual satisfaction, and therefore deserves clinical application.
authors.affiliation: Department of Urology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.forename: Yi-Jun
authors.initials: YJ
authors.lastname: Shen
authors.forename: Tie-Qun
authors.initials: TQ
authors.lastname: Liu
authors.forename: Meng
authors.initials: M
authors.lastname: Ma
authors.forename: Shi-Jun
authors.initials: SJ
authors.lastname: Zhang
authors.forename: Yi-Xin
authors.initials: YX
authors.lastname: Wang
authors.forename: Ru-Hui
authors.initials: RH
authors.lastname: Tian
authors.forename: Hui-Xing
authors.initials: HX
authors.lastname: Chen
authors.forename: Ping
authors.initials: P
authors.lastname: Ping
authors.forename: Xiang-Feng
authors.initials: XF
authors.lastname: Chen
authors.forename: Zheng
authors.initials: Z
authors.lastname: Li
authors.forename: Zheng
authors.initials: Z
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D007172:Erectile Dysfunction / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010413:Penis; D058986:Phosphodiesterase 5 Inhibitors / Q000627:therapeutic use; D017211:Treatment Failure; D016896:Treatment Outcome; D014618:Vacuum
chemical_list: D058986:Phosphodiesterase 5 Inhibitors