title: [Abnormal semen liquefaction and seminal plasma lipoprotein (a)].
abstract: OBJECTIVE
  To explore the effect of seminal plasma lipoprotein (a) in abnormal semen liquefaction and its clinical significance.
  
  
  METHODS
  According to The WHO Laboratory Manual for the Examination and Processing of Human Semen, we conducted semen routine analyses of 101 patients with abnormal semen liquefaction and 26 normal healthy controls. We added chymotrypsin to the semen for 30 minutes of incubation at 37 degrees C. When there were filaments, we centrifuged the semen and obtained the upper seminal plasma to determine the level of lipoprotein (a).
  
  
  RESULTS
  The level of lipoprotein (a) was significantly higher in the 101 patients ([526.2 +/- 243.5] mg/L) than in the 26 normal controls ([296.9 +/- 105.2] mg/L) (P < 0.01) .
  
  
  CONCLUSIONS
  Lipoprotein (a) can inhibit fibrin dissolution, and delayed fibrin dissolution in semen liquefaction may be related to the increased level of seminal plasma lipoprotein (a). The seminal plasma lipoprotein (a) level should be taken into account in the clinical diagnosis of male infertility caused by abnormal semen liquefaction.
authors.affiliation: Department of Laboratory Science, Xiangyang Hospital Affiliated to Hubei University of Traditional Chinese Medicine, Xiangyang, Hubei 441000, China. xf6lfx@sina.com
authors.forename: Fu-Xin
authors.initials: FX
authors.lastname: Liu
authors.forename: Da-Lin
authors.initials: DL
authors.lastname: Su
authors.forename: Guo-Yong
authors.initials: GY
authors.lastname: Zhu
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D006801:Humans; D007248:Infertility, Male / Q000378:metabolism / Q000503:physiopathology*; D017270:Lipoprotein(a) / Q000032:analysis*; D008297:Male; D012661:Semen / Q000378:metabolism*; D029589:Seminal Plasma Proteins / Q000032:analysis; D055815:Young Adult
chemical_list: D017270:Lipoprotein(a); D029589:Seminal Plasma Proteins