title: 5 α-reductase type 2 deficiency: response to dihydrotestosterone gel.
abstract: 5α-reductase (5α-R) deficiency is an important cause of ambiguious genitalia in genetic males; however therapeutic experience in literature is limited. In this report authors describe a child with 46 XY Disorder of Sexual Differentiation (DSD), due to 5α-reductase deficiency, who was managed with Dihydrotestosterone (DHT) gel.
authors.affiliation: Department of Endocrinology, Konaseema Institute of Medical Sciences, Amalapuram, India, drmadhavaiims@rediffmail.com.
authors.forename: Madhavarao
authors.initials: M
authors.lastname: Vupputuri
authors.forename: Madhurima
authors.initials: M
authors.lastname: Kandepu
authors.forename: Harikishore Reddy
authors.initials: HR
authors.lastname: Devireddy
mesh_terms: D000279:Administration, Cutaneous; D042944:Cholestenone 5 alpha-Reductase / Q000172:deficiency*; D013196:Dihydrotestosterone / Q000008:administration & dosage*; D012734:Disorders of Sex Development / Q000188:drug therapy*; D005782:Gels; D006801:Humans; D007223:Infant; D008297:Male
chemical_list: D005782:Gels; D013196:Dihydrotestosterone; D042944:Cholestenone 5 alpha-Reductase