title: Cell biology: DUBing CP110 controls centrosome numbers.
abstract: Accurate control of centrosome number is critical for the maintenance of genomic integrity. A recent study reveals that the deubiquitinating enzyme USP33 regulates centrosome biogenesis by stabilizing the centriolar protein CP110.
authors.affiliation: Cell Cycle Control and Carcinogenesis, F045, German Cancer Research Center, DKFZ, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany.
authors.forename: Felix
authors.initials: F
authors.lastname: Bärenz
authors.forename: Ingrid
authors.initials: I
authors.lastname: Hoffmann
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins / Q000378:metabolism*; D018385:Centrosome / Q000378:metabolism*; D006801:Humans; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D010750:Phosphoproteins / Q000378:metabolism*; D043222:Ubiquitin Thiolesterase / Q000378:metabolism*; D054875:Ubiquitination
chemical_list: D018797:Cell Cycle Proteins; D008869:Microtubule-Associated Proteins; D010750:Phosphoproteins; D043222:Ubiquitin Thiolesterase