title: [What Must the (Abdominal) Surgeon Know about Experimental Medicine (?) - Translational Research in General (Abdominal) Surgery(Viszeral-)Chirurg & experimentelle Medizin].
abstract: Experimental medicine has evolved tremendously in the last few years. In particular, the introduction of novel techniques, in-vitro models, knock-out/transgenic animals and high-through put analytical methodologies have resulted in a deeper understanding of cellular pathophysiology and diseases. The daily clinical management has benefited by the introduction of biomarkers and targeted therapies. This development has been accompanied by increasing specialisation across all fields of research and medicine. Therefore, clinical-translational research requires a team of competent partners nowadays. The visceral surgeon can contribute significantly to these projects. The present review highlights several aspects of translational research and put chances and potential pitfalls into perspective in context with the work of the visceral surgeon.
authors.affiliation: Klinik für Gastroenterologie, Hepatologie & Infektiologie, Universitätsklinikum Magdeburg A. ö. R., Magdeburg, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Wex
authors.affiliation: Institut für Pathologie, Universitätsklinikum Magdeburg A. ö. R., Magdeburg, Deutschland.
authors.forename: D
authors.initials: D
authors.lastname: Kuester
authors.affiliation: Klinik für Allgemein-, Viszeral- & Gefäßchirurgie, Universitätsklinikum Magdeburg A. ö. R., Magdeburg, Deutschland.
authors.forename: F
authors.initials: F
authors.lastname: Meyer
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000193:education*; D002983:Clinical Competence; D003479:Curriculum; D004059:Diffusion of Innovation; D013505:Digestive System Surgical Procedures / Q000193:education*; D004502:Education, Medical, Continuing; D005826:Genetics, Medical / Q000193:education*; D005858:Germany; D006801:Humans; D007396:Internship and Residency; D013043:Specialties, Surgical / Q000193:education*; D057170:Translational Research, Biomedical