title: Development and validation of a food frequency questionnaire to estimate the intake of genistein in Malaysia.
abstract: OBJECTIVE
  To develop and validate a food frequency questionnaire (FFQ) to estimate the genistein intake in a Malaysian population of pregnant women.
  
  
  METHODS
  A single 24-h dietary recall was obtained from 40 male and female volunteers. A FFQ of commonly consumed genistein-rich foods was developed from these recalls, and a database of the genistein content of foods found in Malaysia was set up. The FFQ was validated against 7-d food diary (FD) kept by 46 pregnant women and against non-fasting serum samples obtained from 64 pregnant women. Reproducibility was assessed by comparing the responses on two FFQs administered approximately 1 month apart.
  
  
  RESULTS
  The Pearson correlation coefficient between FFQ1 and FD was 0.724 and that between FFQ2 and FD was 0.807. Classification into the same or adjacent quintiles was 78% for FFQ1 versus FD and 88% for FFQ2 versus FD. A significant dose -- response relation was found between FFQ-estimated genistein intake and serum levels.
  
  
  CONCLUSIONS
  The FFQ developed is a reliable, valid tool for categorising people by level of genistein intake.
authors.affiliation: Department of Physiology, Faculty of Medicine, University of Malaya and.
authors.forename: Anne R
authors.initials: AR
authors.lastname: Fernandez
authors.forename: Siti Zawiah
authors.initials: SZ
authors.lastname: Omar
authors.forename: Ruby
authors.initials: R
authors.lastname: Husain
mesh_terms: D000328:Adult; D004032:Diet; D015930:Diet Records; D004034:Diet Surveys / Q000592:standards*; D005260:Female; D019833:Genistein / Q000008:administration & dosage* / Q000097:blood; D006801:Humans; D008296:Malaysia; D008297:Male; D011247:Pregnancy; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires / Q000592:standards*; D055815:Young Adult
chemical_list: D019833:Genistein