title: Antigenic and genetic analyses of isolate APMV/wigeon/Italy/3920-1/2005 indicate that it represents a new avian paramyxovirus (APMV-12).
abstract: Isolate wigeon/Italy/3920-1/2005 (3920-1) was obtained during surveillance of wild birds in November 2005 in the Rovigo province of Northern Italy and shown to be a paramyxovirus. Analysis of cross-haemagglutination-inhibition tests between 3920-1 and representative avian paramyxoviruses showed only a low-level relationship to APMV-1. Phylogenetic analysis of the whole genome and each of the six genes indicated that while 3920-1 grouped with APMV-1 and APMV-9 viruses, it was quite distinct from these two. In the whole-genome analysis, 3920-1 had 52.1 % nucleotide sequence identity to the closest APMV-1 virus, 50.1 % identity to the APMV-9 genome, and less than 42 % identity to representatives of the other avian paramyxovirus groups. We propose isolate wigeon/Italy/3920-1/2005 as the prototype strain of a further APMV group, APMV-12.
authors.affiliation: OIE/FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Università, 10-35020, Legnaro, PD, Italy, cterregino@izsvenezie.it.
authors.forename: C
authors.initials: C
authors.lastname: Terregino
authors.forename: E W
authors.initials: EW
authors.lastname: Aldous
authors.forename: A
authors.initials: A
authors.lastname: Heidari
authors.forename: C M
authors.initials: CM
authors.lastname: Fuller
authors.forename: R
authors.initials: R
authors.lastname: De Nardi
authors.forename: R J
authors.initials: RJ
authors.lastname: Manvell
authors.forename: M S
authors.initials: MS
authors.lastname: Beato
authors.forename: W M
authors.initials: WM
authors.lastname: Shell
authors.forename: I
authors.initials: I
authors.lastname: Monne
authors.forename: I H
authors.initials: IH
authors.lastname: Brown
authors.forename: D J
authors.initials: DJ
authors.lastname: Alexander
authors.forename: I
authors.initials: I
authors.lastname: Capua
mesh_terms: D000818:Animals; D018109:Avulavirus / Q000145:classification* / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity; D045463:Avulavirus Infections / Q000662:veterinary* / Q000821:virology; D001715:Bird Diseases / Q000821:virology*; D002645:Chickens / Q000821:virology; D004372:Ducks / Q000821:virology*; D016679:Genome, Viral; D006385:Hemagglutination Inhibition Tests; D007114:Immunization; D007558:Italy; D010802:Phylogeny; D011201:Poultry Diseases / Q000276:immunology / Q000517:prevention & control / Q000821:virology; D012367:RNA, Viral / Q000235:genetics; D017422:Sequence Analysis, DNA
chemical_list: D012367:RNA, Viral