title: A case of cluster headache treated with rotigotine: clinical and neurophysiological correlates.
abstract: BACKGROUND
  Chronic cluster headache (CCH) is characterized by recurrent bouts of facial pain lasting up to 180 minutes in the absence of a long remission period.
  
  
  METHODS
  We report the case of a 43-year-old male patient with treatment-resistant CCH, who improved with administration of transdermal rotigotine. We also evaluated the nociceptive blink reflex habituation that was reduced before the treatment (as is usual in CH patients) and normalized by transdermal rotigotine.
  
  
  CONCLUSIONS
  We suggest that rotigotine could represent a further therapeutic option in the treatment of drug-resistant CCH.
authors.affiliation: Don Carlo Gnocchi Onlus Foundation, Italy.
authors.forename: Cherubino
authors.initials: C
authors.lastname: Di Lorenzo
authors.forename: Gianluca
authors.initials: G
authors.lastname: Coppola
authors.forename: Francesco
authors.initials: F
authors.lastname: Pierelli
mesh_terms: D000328:Adult; D001767:Blinking / Q000187:drug effects / Q000502:physiology; D003027:Cluster Headache / Q000188:drug therapy*; D018491:Dopamine Agonists / Q000008:administration & dosage*; D006185:Habituation, Psychophysiologic / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008297:Male; D013764:Tetrahydronaphthalenes / Q000008:administration & dosage*; D013876:Thiophenes / Q000008:administration & dosage*; D057968:Transdermal Patch
chemical_list: D018491:Dopamine Agonists; D013764:Tetrahydronaphthalenes; D013876:Thiophenes; C047508:rotigotine
keywords: Cluster headache; blink reflex; dopamine agonist; habituation; prophylaxis; rotigotine