title: Aptamer degradation inhibition combined with DNAzyme cascade-based signal amplification for colorimetric detection of proteins.
abstract: Combining the inhibition of aptamer degradation with DNA Enzyme (DNAzyme) cascade-based signal amplification, a label-free and sensitive colorimetric protein assay strategy was proposed.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, PR China. jishanli@hnu.cn
authors.forename: Jishan
authors.initials: J
authors.lastname: Li
authors.forename: Yuhua
authors.initials: Y
authors.lastname: Jia
authors.forename: Jing
authors.initials: J
authors.lastname: Zheng
authors.forename: Wenwan
authors.initials: W
authors.lastname: Zhong
authors.forename: Guoli
authors.initials: G
authors.lastname: Shen
authors.forename: Ronghua
authors.initials: R
authors.lastname: Yang
authors.forename: Weihong
authors.initials: W
authors.lastname: Tan
mesh_terms: D052157:Aptamers, Nucleotide / Q000378:metabolism*; D000077214:Becaplermin; D001681:Biological Assay; D015415:Biomarkers / Q000032:analysis; D003124:Colorimetry; D021881:DNA, Catalytic / Q000378:metabolism*; D005090:Exodeoxyribonucleases / Q000378:metabolism*; D053758:Nanoparticles; D019095:Point-of-Care Systems; D020574:Proto-Oncogene Proteins c-sis / Q000032:analysis* / Q000378:metabolism
chemical_list: D052157:Aptamers, Nucleotide; D015415:Biomarkers; D021881:DNA, Catalytic; D020574:Proto-Oncogene Proteins c-sis; D000077214:Becaplermin; D005090:Exodeoxyribonucleases; C028450:exodeoxyribonuclease I