title: Copper-promoted Sandmeyer trifluoromethylation reaction.
abstract: A copper-promoted trifluoromethylation reaction of aromatic amines is described. This transformation proceeds smoothly under mild conditions and exhibits good tolerance of many synthetically relevant functional groups. It provides an alternative approach for the synthesis of trifluoromethylated arenes and heteroarenes. It also constitutes a new example of the Sandmeyer reaction.
authors.affiliation: Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.
authors.forename: Jian-Jun
authors.initials: JJ
authors.lastname: Dai
authors.forename: Chi
authors.initials: C
authors.lastname: Fang
authors.forename: Bin
authors.initials: B
authors.lastname: Xiao
authors.forename: Jun
authors.initials: J
authors.lastname: Yi
authors.forename: Jun
authors.initials: J
authors.lastname: Xu
authors.forename: Zhao-Jing
authors.initials: ZJ
authors.lastname: Liu
authors.forename: Xi
authors.initials: X
authors.lastname: Lu
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.forename: Yao
authors.initials: Y
authors.lastname: Fu
mesh_terms: D000588:Amines / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis / Q000737:chemistry*; D008745:Methylation; D008958:Models, Molecular; D015394:Molecular Structure
chemical_list: D000588:Amines; D006845:Hydrocarbons, Fluorinated; D003300:Copper