title: Embryonal rhabdomyosarcoma of the uterine cervix in a 41-year-old woman: a deceptively benign entity.
abstract: Rhabdomyosarcoma (RMS) of the cervix in women older than 40 years of age is extremely rare. Embryonal RMS can appear deceptively benign both clinically and histopathologically. Diagnosis is made on the basis of histomorphologic and immunohistochemical findings. A high index of suspicion is, however, needed to make the diagnosis, as they can masquerade as benign polyps. A 41-year-old female with cervical RMS is described here. The initial biopsy diagnosis of embryonal RMS was confirmed on subsequent hysterectomy. The present case report is described with emphasis on histopathologic features and diagnostic difficulties along with a brief review of the literature.
authors.affiliation: Department of Pathology, Sir Ganga Ram Hospital, New Delhi, India.
authors.forename: Sunila
authors.initials: S
authors.lastname: Jain
authors.forename: Kanika
authors.initials: K
authors.lastname: Jain
authors.forename: Prem
authors.initials: P
authors.lastname: Chopra
mesh_terms: D000328:Adult; D001706:Biopsy; D002584:Cervix Uteri / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D003893:Desmin / Q000378:metabolism; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007044:Hysterectomy; D018008:Myogenin / Q000378:metabolism; D011127:Polyps / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D018233:Rhabdomyosarcoma, Embryonal / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
chemical_list: D003893:Desmin; D018008:Myogenin