title: Synthesis of a functionalizable water-soluble cryptophane-111.
abstract: The development of optimized xenon host systems is of crucial importance for the success of molecular imaging using hyperpolarized (129)Xe MRI. Cryptophane-111 is a promising candidate because of its encapsulation properties. The synthesis of cryptophane-111-based biosensors requires both water-solubilizing and chemically activatable groups. An expeditious synthesis of a water-soluble and functionalizable cryptophane-111 is described.
authors.affiliation: CEA, iBiTec-S/SCBM, LabEx LERMIT, F-91191 Gif-sur-Yvette, France.
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Dubost
authors.forename: Naoko
authors.initials: N
authors.lastname: Kotera
authors.forename: Sébastien
authors.initials: S
authors.lastname: Garcia-Argote
authors.forename: Yves
authors.initials: Y
authors.lastname: Boulard
authors.forename: Estelle
authors.initials: E
authors.lastname: Léonce
authors.forename: Céline
authors.initials: C
authors.lastname: Boutin
authors.forename: Patrick
authors.initials: P
authors.lastname: Berthault
authors.forename: Christophe
authors.initials: C
authors.lastname: Dugave
authors.forename: Bernard
authors.initials: B
authors.lastname: Rousseau
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D011083:Polycyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D012997:Solvents / Q000737:chemistry*; D014867:Water / Q000737:chemistry*; D014978:Xenon / Q000737:chemistry*
chemical_list: D011083:Polycyclic Compounds; D012997:Solvents; C568309:cryptophane-111; D014867:Water; D014978:Xenon