title: Post-staphylococcal infection Henoch-Schönlein purpura nephritis: a case report and review of the literature.
abstract: A 37-year-old man developed Henoch--Schönlein purpura nephritis (HSPN) with nephrotic syndrome and rapidly progressive glomerulonephritis after otitis media and externa due to methicillin-resistant Staphylococcus aureus infection. Despite resolution of the infection and prednisolone therapy, his kidney disease worsened. However, the addition of cyclosporine A finally resulted in complete remission of the nephrotic syndrome. A review of similar cases with post-Staphylococcal infection HSPN revealed strong similarities between this entity and immunoglobulin A-dominant postinfectious glomerulonephritis (IgA-PIGN), an increasingly recognized form of PIGN typically associated with Staphylococcal infection, in both clinical and morphological features. Post-Staphylococcal infection HSPN may constitute a subgroup of IgA-PIGN.
authors.affiliation: Department of Nephrology, Yokosuka Kyosai Hospital, Kanagawa, Japan. shintaro_mandai@yahoo.co.jp
authors.forename: Shintaro
authors.initials: S
authors.lastname: Mandai
authors.forename: Makoto
authors.initials: M
authors.lastname: Aoyagi
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Nagahama
authors.forename: Yohei
authors.initials: Y
authors.lastname: Arai
authors.forename: Suguru
authors.initials: S
authors.lastname: Hirasawa
authors.forename: Shota
authors.initials: S
authors.lastname: Aki
authors.forename: Naoto
authors.initials: N
authors.lastname: Inaba
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tanaka
authors.forename: Yukio
authors.initials: Y
authors.lastname: Tsuura
authors.forename: Teiichi
authors.initials: T
authors.lastname: Tamura
authors.forename: Sei
authors.initials: S
authors.lastname: Sasaki
mesh_terms: D000328:Adult; D016572:Cyclosporine / Q000627:therapeutic use; D005921:Glomerulonephritis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications* / Q000382:microbiology; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D011239:Prednisolone / Q000627:therapeutic use; D013203:Staphylococcal Infections / Q000150:complications* / Q000382:microbiology
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011239:Prednisolone