title: Neuroglobin: neuroprotection and neurogenesis.
abstract: Globins, such as hemoglobin, serve as oxygen sensors. Neuroglobin is the globin in brain. It is induced by ischemia and is protective in modeled stroke. Here, Haines et al. describe an additional property of neuroglobin, its expression in progenitor cell populations in brain during development. A physiologic role is offered but other data show progenitor cells response to injury and their neurotropic properties in ischemic brain.
authors.affiliation: Medicine (Neurology) and Neurobiology, Morehouse School of Medicine, United States. rsimon@msm.edu
authors.forename: Roger
authors.initials: R
authors.lastname: Simon
mesh_terms: D000818:Animals; D005914:Globins / Q000378:metabolism*; D006801:Humans; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D058953:Neural Stem Cells / Q000378:metabolism*; D055495:Neurogenesis / Q000502:physiology*; D000078787:Neuroglobin; D009474:Neurons / Q000378:metabolism*
chemical_list: D009419:Nerve Tissue Proteins; D000078787:Neuroglobin; D005914:Globins
keywords: Development; Doublecortin; Neuroglobin; Progenitor; Subventricular zone