title: Interventions for lifestyle changes to promote weight reduction, a randomized controlled trial in primary health care.
abstract: BACKGROUND
  Overweight and obesity are growing public health problems in high income countries and is now growing at a dramatic pace in low and middle income countries, particularly in urban settings. The aim of this trial was to examine the effects of a weight reduction program in adults and to determine whether or not a more extensive intervention was superior to ordinary care.
  
  
  METHODS
  Patients seeking advice for overweight/obesity or illness related to overweight/obesity at eight primary health care centers in Sweden were randomized either to intervention or control care groups with both groups given dietary advice and individualized information on increased regular physical activity. In the intervention group advice was more extensive and follow-up more frequent than in the control group during the study period of two years. Main outcome measure was reduction in body weight of five percent or more from study start.
  
  
  RESULTS
  From October 2004 to April 2006, 133 patients, 67 in the intervention group and 66 in the control group, were randomized over a period of 18 months. Target weight was achieved at 12 months by 26.7% of the patients in the intervention group compared with 18.4% in the control group (p = 0.335). There was an average absolute weight loss of 2.5 kg in the intervention group and 0.8 kg in the control group at 12 months as compared with the weight at study entry. There were no significant differences between the groups in quality of life, blood glucose and lipids. At 24 months target weight was achieved in 21.9% versus 15.6%, with an average weight reduction of 1.9 kg and 1.2 kg in the two groups, respectively.
  
  
  CONCLUSIONS
  Promotion of a diet with limited energy intake, appropriate composition of food and increased physical activity had limited effects on body weight in a Swedish primary care setting. More extensive advice and more frequent visits made no significant difference to the outcome.
  
  
  BACKGROUND
  ClinicalTrial.gov: NCT01606917.
authors.forename: Stefan Po
authors.initials: SP
authors.lastname: Jansson
authors.forename: Peter
authors.initials: P
authors.lastname: Engfeldt
authors.forename: Anders
authors.initials: A
authors.lastname: Magnuson
authors.forename: Georg Lohse
authors.initials: GL
authors.lastname: Pt
authors.forename: Göran
authors.initials: G
authors.lastname: Liljegren
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000628:therapy; D011320:Primary Health Care; D013548:Sweden; D015431:Weight Loss; D055815:Young Adult