title: [Risk factors analysis of primary open angle glaucoma in women].
abstract: OBJECTIVE
  To explore the risk factors of primary open angle glaucoma (POAG) in women.
  
  
  METHODS
  This retrospective, case-control study collected 128 female patients with POAG and 142 female with normal controls without POAG from 2009 to 2010. The risk factors including family history, hypertension, diabetes, age of menarche, age of menopause, parity, oral contraceptive (OC) use, hormone therapy were analyzed by logistic regression analysis.
  
  
  RESULTS
  Compared with normal control group using logistic regression analysis, there were significant differences in such risk factors in POAG group as family history (OR = 43.36, 95%CI: 5.69 - 346.67; P < 0.001), hypertension(OR = 3.29, 95%CI: 1.82 - 5.94; P < 0.001), age of menarche (OR = 2.046, 95%CI: 1.17 - 3.54; P = 0.011), age of menopause (OR = 0.57, 95%CI: 0.32 - 0.99; P = 0.049), hormone therapy (OR = 0.29, 95%CI: 0.09 - 0.92; P = 0.036).
  
  
  CONCLUSIONS
  Family history and hypertension are high risk factors to develop POAG for women. However, female hormones may play a protective role in women with POAG.
authors.affiliation: Department of nursing, Huashan Hospital of Fudan University, Shanghai, China.
authors.forename: Shi-yuan
authors.initials: SY
authors.lastname: Dong
authors.forename: Yi-bing
authors.initials: YB
authors.lastname: Si
authors.forename: Yu-yan
authors.initials: YY
authors.lastname: Zhang
authors.forename: Gen-ming
authors.initials: GM
authors.lastname: Zhao
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D005902:Glaucoma, Open-Angle / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D011795:Surveys and Questionnaires