title: [Relation of neutrophil/lymphocyte ratio with the presence and severity of coronary artery ectasia].
abstract: OBJECTIVE
  It has been shown that the neutrophil to lymphocyte ratio (N/L ratio) is associated with cardiovascular events and mortality. In this study, we investigated the N/L ratio in patients with coronary artery ectasia (CAE).
  
  
  METHODS
  Fifty patients diagnosed with CAE using coronary angiography were included in the study (29 male, 21 female; mean age, 51.1±7.1 years). The control group consisted of 28 patients who had normal coronary arteries as determined by coronary angiography (16 male, 12 female; mean age, 49.5±9.4 years). Basal characteristics were recorded. The number of ectatic segments was noted. Hematologic parameters were measured and the N/L ratio was calculated.
  
  
  RESULTS
  The N/L ratio was significantly higher in the CAE group compared with control group (median [25-75% percentile] 2.2 [1.6-3.0] vs. 1.8 [1.4-2.0], p=0.014, respectively). The Spearman correlation analysis demonstrated that the N/L ratio positively correlated with number of ectatic segments (r=0.35; p<0.002). Multivariable logistic regression analysis showed an independent relationship between CAE and the N/L ratio (odds ratio 2.674, 95% confidence interval 1.184-6.039, p=0.018).
  
  
  CONCLUSIONS
  The N/L ratio is higher in patients with CAE. This ratio is related to presence and severity of CAE.
authors.affiliation: Department of Cardiology, Abant İzzet Baysal University, Faculty of Medicine, Bolu, Turkey. ssayhan@yahoo.com
authors.forename: S Selim
authors.initials: SS
authors.lastname: Ayhan
authors.forename: Serkan
authors.initials: S
authors.lastname: Oztürk
authors.forename: Alim
authors.initials: A
authors.lastname: Erdem
authors.forename: Mehmet Fatih
authors.initials: MF
authors.lastname: Ozlü
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ozyaşar
authors.forename: Kemalettin
authors.initials: K
authors.lastname: Erdem
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yazıcı
mesh_terms: D016022:Case-Control Studies; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000473:pathology*; D004108:Dilatation, Pathologic / Q000097:blood* / Q000000981:diagnostic imaging / Q000401:mortality; D005260:Female; D006801:Humans; D016015:Logistic Models; D008214:Lymphocytes / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000166:cytology*; D012720:Severity of Illness Index