title: Efficacy of antibiotic prophylaxis for preventing intrathoracic infections, after thoracostomy, for traumatic haemo/pneumothorax - experience of Oradea county emergency hospital.
abstract: The aim of the paper is to observe the effectiveness of prophylactic administration of antibacterials against empyema and pneumonia after tube thoracostomy for traumatic collections.
  
  
  METHODS
  Observational retrospective study over a ten years period (2002-2011), at the Oradea County Emergency Hospital on 939 patients with chest tube drainage for traumatic haemo/pneumothoraces. The morbidity by intrathoracic infections was 5,5% in the curative antibiotic group.
  
  
  RESULTS
  The median number of risk factors for surgical infections and case severity were not statistically different (p=0.9653 and p=0,6601) between cases with antibioprophylaxis and curative treatment, but the incidence of intrathoracic infection in the prophylaxis group (n=86) was half (2,3%). Antibioprophylaxis was effective in over 95% of the cases and it associated in-hospital length of stay, length of stay in the ICU and costs of care significantly (p<0.0001, p<0.0001, p=0.0046) lesser than of those patients treated with curative regimen. The overall mortality was 8.6% within the curative regimen group with an attributable mortality to infections of 17.39%; but it was only 2.3% and respectively 0 within the prophylaxis group.
  
  
  CONCLUSIONS
  Antibiotic prophylaxis for intrathoracic infections after tube thoracostomy for traumatic collections was justified by case severity and risk factors and was effective and cost-efficient, but it should be administered selectively.
authors.affiliation: Faculty of Medicine and Pharmacy Oradea.
authors.forename: D
authors.initials: D
authors.lastname: Grigorescu
authors.forename: A
authors.initials: A
authors.lastname: Maghiar
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D015505:Chest Tubes / Q000009:adverse effects; D004636:Emergency Service, Hospital; D016724:Empyema, Pleural / Q000401:mortality / Q000517:prevention & control*; D006468:Hemopneumothorax / Q000188:drug therapy* / Q000209:etiology / Q000601:surgery*; D006766:Hospitals, County; D006801:Humans; D015994:Incidence; D007902:Length of Stay; D018410:Pneumonia, Bacterial / Q000401:mortality / Q000517:prevention & control*; D012189:Retrospective Studies; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D013898:Thoracic Injuries / Q000150:complications / Q000601:surgery*; D013907:Thoracostomy / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents