title: Individualized glycaemic targets and pharmacotherapy in type 2 diabetes.
abstract: The Global Partnership for Effective Diabetes Management, established to provide practical guidance to improve patient outcomes in diabetes, has developed and modified recommendations to improve glycaemic control in type 2 diabetes. The Global Partnership advocates an individualized therapeutic approach and, as part of the process to customize therapy, has previously identified specific type 2 diabetes patient subgroups that require special consideration. This article builds on earlier publications, expanding the scope of practical guidance to include newly diagnosed individuals with complications and women with diabetes in pregnancy. Good glycaemic control remains the cornerstone of managing type 2 diabetes, and plays a vital role in preventing or delaying the onset and progression of diabetic complications. Individualizing therapeutic goals and treatments to meet glycaemic targets safely and without delay remains paramount, in addition to a wider programme of care to reduce cardiovascular risk factors and improve patient outcomes.
authors.affiliation: Diabetes Research, School of Life & Health Sciences, Aston University, Birmingham, UK. c.j.bailey@aston.ac.uk
authors.forename: Clifford J
authors.initials: CJ
authors.lastname: Bailey
authors.forename: Pablo
authors.initials: P
authors.lastname: Aschner
authors.forename: Stefano
authors.initials: S
authors.lastname: Del Prato
authors.forename: James
authors.initials: J
authors.lastname: LaSalle
authors.forename: Linong
authors.initials: L
authors.lastname: Ji
authors.forename: Stephan
authors.initials: S
authors.lastname: Matthaei
mesh_terms: D001786:Blood Glucose / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D017410:Practice Guidelines as Topic / Q000592:standards; D057285:Precision Medicine / Q000379:methods; D016896:Treatment Outcome
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents
keywords: Global Partnership; Glycaemic targets; HbA1c; individualized therapy; type 2 diabetes