title: [Dynamics of morphological and functional development of ovarian tissue allografts].
abstract: We examined the dynamics of folliculogenesis in ovarian tissue allograft and its endocrine function in an organism of castrated recipient rats during 100 days. Growth and development of ovarian tissue and its steroidogenic function in heterotopic transplantation were determined by its initial morphological organization. Allotransplantation of mature ovarian tissue was found to cause preservation of its morphological structure, whereas the transplantation of neonatal ovarian tissue caused formation of follicular cysts. At 100th day of observation, we observed a recovery of the levels of sex hormones to the physiological norm after transplantation of both mature ovarian tissue and neonatal tissue of 10-days of postnatal development.
authors.forename: Iu O
authors.initials: IuO
authors.lastname: Tishchenko
authors.forename: V V
authors.initials: VV
authors.lastname: Kiroshka
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D015925:Cryopreservation; D004958:Estradiol / Q000097:blood; D005260:Female; D006085:Graft Survival / Q000502:physiology; D007668:Kidney; D010052:Ovariectomy; D010053:Ovary / Q000378:metabolism / Q000637:transplantation* / Q000648:ultrastructure*; D011374:Progesterone / Q000097:blood; D051381:Rats; D013739:Testosterone / Q000097:blood; D016042:Transplantation, Heterotopic; D014184:Transplantation, Homologous
chemical_list: D013739:Testosterone; D011374:Progesterone; D004958:Estradiol