title: Effectiveness of coating acrylic resin dentures on preventing Candida adhesion.
abstract: OBJECTIVE
  The aim of this study was to prevent the adhesion of C. albicans on acrylic resin dentures by modifying their surfaces.
  
  
  METHODS
  Ninety acrylic resin plates were divided into three groups. Group I: conventionally processed acrylic resin plates. Group II: plates painted with 2-Octyl Cyanoacrylate adhesive. Group III: plates painted with Adper Single Bond Adhesive. All specimens were immersed separately in containers filled with artificial saliva that contained C. albicans and then incubated for 11 days at 37°C. Three methods of evaluation were used to count the adhered Candida: direct culture, slide count, and serial dilutions.
  
  
  RESULTS
  C. albicans in 1/10, 1/10², and 1/10³ dilutions showed overgrowth in group I, while overgrowth was noted only with 1/10 dilution in group III. For group III, mean colony numbers of 123, 22, 3.4, and 0 were found for the 1/10², 1/10³, 1/10⁴, and 1/10⁵ dilutions, respectively. Regarding the slide counts, group I showed a mean fungal count of 166 compared to 40 for group III with 1/10 dilution, 21 compared to 9 with 1/10³ dilution, 8.6 compared to 0.7 with 1/10³ dilution, and 1.2 compared to 0 with 1/10⁴ dilution. No plates in group II showed any candidal colonies regardless of the method of evaluation (0%). These differences were statistically significant (p < 0.0001).
  
  
  CONCLUSIONS
  Coating the acrylic resin dentures with Adper Single Bond Adhesive was effective in reducing C. albicans adhesion to dentures, while coating with 2-Octyl Cyanoacrylate adhesive completely inhibited such adhesion.
authors.affiliation: Department of Biomedical Dental Sciences, College of Dentistry, University of Dammam, Saudi Arabia. aiman.a.ali@gmail.com
authors.forename: Aiman A
authors.initials: AA
authors.lastname: Ali
authors.forename: Fahad A
authors.initials: FA
authors.lastname: Alharbi
authors.forename: C S
authors.initials: CS
authors.lastname: Suresh
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D018441:Biofilms; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry; D002176:Candida albicans / Q000254:growth & development / Q000502:physiology*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D015169:Colony Count, Microbial; D003487:Cyanoacrylates / Q000737:chemistry; D003764:Dental Materials / Q000737:chemistry*; D003819:Denture Bases / Q000382:microbiology*; D006801:Humans; D008768:Methylmethacrylates / Q000737:chemistry; D012464:Saliva, Artificial / Q000737:chemistry; D013499:Surface Properties; D013696:Temperature; D013997:Time Factors; D014014:Tissue Adhesives / Q000737:chemistry
chemical_list: D000180:Acrylic Resins; D020099:Coated Materials, Biocompatible; D003487:Cyanoacrylates; D003764:Dental Materials; D008768:Methylmethacrylates; D012464:Saliva, Artificial; D014014:Tissue Adhesives; C115612:single bond; D017438:Bisphenol A-Glycidyl Methacrylate; C100832:octyl 2-cyanoacrylate; C029883:Trevalon universal
keywords: Candida adhesion; Candida albicans; Denture stomatitis; bond adhesive