title: Effects of different levels of physical inactivity on plasma visfatin in healthy normal-weight men.
abstract: We tested whether physical inactivity (PI) is an independent predictor of plasma visfatin, a newly discovered adipokine likely involved in the relationship between obesity-associated low-grade inflammation and insulin resistance. PI was induced in healthy men (Body Mass Index = 23.4 ± 0.6 kg·m(-2)) by 10 days of confinement (n = 8), 1 month of detraining (n = 10), and 3 months of bed rest with (n = 7) and without exercise (n = 8). Visfatin was negatively associated with activity energy expenditure (p = 0.03). No relationship was observed with insulin sensitivity. This suggested that PI itself increases visfatin concentrations.
authors.affiliation: Université de Strasbourg, Institut Pluridisciplinaire Hubert Curien (IPHC), 23, rue Becquerel, 67087 Strasbourg, France, Centre National de la Recherche Scientifique (CNRS), Unité mixte de recherche (UMR) 7178, 67087 Strasbourg, France.
authors.forename: Floriane
authors.initials: F
authors.lastname: Rudwill
authors.forename: Stéphane
authors.initials: S
authors.lastname: Blanc
authors.forename: Guillemette
authors.initials: G
authors.lastname: Gauquelin-Koch
authors.forename: Alexander
authors.initials: A
authors.lastname: Choukèr
authors.forename: Martina
authors.initials: M
authors.lastname: Heer
authors.forename: Chantal
authors.initials: C
authors.lastname: Simon
authors.forename: Audrey
authors.initials: A
authors.lastname: Bergouignan
mesh_terms: D015992:Body Mass Index; D015444:Exercise; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D054409:Nicotinamide Phosphoribosyltransferase; D009765:Obesity / Q000097:blood
chemical_list: D054409:Nicotinamide Phosphoribosyltransferase