title: An outbreak of Burkholderia multivorans beyond cystic fibrosis patients.
abstract: Strains of the Burkholderia cepacia complex (Bcc) are opportunistic pathogens capable of causing serious infection in cystic fibrosis patients. Recently we identified a suspected outbreak of infection with Bcc strains at the University Hospital Olomouc. Seventy-four Bcc strains were isolated from 52 patients, most of whom (N = 48) did not suffer from cystic fibrosis. Most frequently (N = 46) Burkholderia multivorans was isolated and 24 (52.2%) of these strains were clonal. Fifteen of these strains were isolated from intensive care patients, five of whom died from hospital-acquired pneumonia. B. multivorans can cause serious outbreaks of infection beyond cystic fibrosis sufferers.
authors.affiliation: Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic.
authors.forename: V
authors.initials: V
authors.lastname: Hanulik
authors.forename: M A
authors.initials: MA
authors.lastname: Webber
authors.forename: M
authors.initials: M
authors.lastname: Chroma
authors.forename: R
authors.initials: R
authors.lastname: Uvizl
authors.forename: O
authors.initials: O
authors.lastname: Holy
authors.forename: R N
authors.initials: RN
authors.lastname: Whitehead
authors.forename: S
authors.initials: S
authors.lastname: Baugh
authors.forename: I
authors.initials: I
authors.lastname: Matouskova
authors.forename: M
authors.initials: M
authors.lastname: Kolar
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019121:Burkholderia Infections / Q000453:epidemiology*; D042602:Burkholderia cepacia complex / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D003428:Cross Infection / Q000453:epidemiology*; D003550:Cystic Fibrosis / Q000150:complications; D018153:Czech Republic / Q000453:epidemiology; D004196:Disease Outbreaks; D005260:Female; D005838:Genotype; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D058889:Molecular Typing; D016019:Survival Analysis