title: Kidney transplantation from donors after brain or cardiac death in China--a clinical analysis of 94 cases.
abstract: BACKGROUND
  We analyzed outcomes of kidney transplantation (KTx) from donation after brain death (DBD) or cardiac death (DCD) in China under the current level of the health care system.
  
  
  METHODS
  Among 94 KTx performed from February 2007 to March 2012 in two organ transplant centers in the south of China, 50 KTx were used DBD and 44 DCD donors. We retrospectively analyzed the clinical outcomes.
  
  
  RESULTS
  At a mean follow-up of 25.5 months, the 1-year and 2-year graft survival rates were 96.8% and 95.2% respectively. Delayed graft function (DGF) occurred in 27.7% recipients, three of whom lost graft function. Among six observed acute rejection episodes, five were reversed. When compared to the DCD group in DBD patients were apt to recover from DGF. Serum creatinine decreased more promptly in the DBD than in DCD group. Serum creatinine in the DCD group increased after months 12, when it was significantly higher than that in the DBD group (P < .05).
  
  
  CONCLUSIONS
  Kidney transplantation from DBD donors showed good outcomes with few complications. Although KTx from DCD donors showed a higher DGF rate and longer duration of graft recovery, we achieved favorable short-term clinical outcome using this source.
authors.affiliation: Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. wcx6363@163.com
authors.forename: C
authors.initials: C
authors.lastname: Wang
authors.forename: L
authors.initials: L
authors.lastname: Liu
authors.forename: Q
authors.initials: Q
authors.lastname: Fu
authors.forename: F
authors.initials: F
authors.lastname: Meng
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: S
authors.initials: S
authors.lastname: Deng
authors.forename: J
authors.initials: J
authors.lastname: Fei
authors.forename: X
authors.initials: X
authors.lastname: Yuan
authors.forename: M
authors.initials: M
authors.lastname: Han
authors.forename: L
authors.initials: L
authors.lastname: Chen
authors.forename: J
authors.initials: J
authors.lastname: Qiu
authors.forename: G
authors.initials: G
authors.lastname: Chen
authors.forename: H
authors.initials: H
authors.lastname: Wang
authors.forename: F
authors.initials: F
authors.lastname: Huo
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: M
authors.initials: M
authors.lastname: Lin
authors.forename: X
authors.initials: X
authors.lastname: He
mesh_terms: D000293:Adolescent; D000328:Adult; D001926:Brain Death; D002648:Child; D003643:Death; D051799:Delayed Graft Function; D005260:Female; D006084:Graft Rejection; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D015996:Survival Rate; D014019:Tissue Donors; D055815:Young Adult