title: Exercise in neuromuscular disease.
abstract: In this review, we present an overview of the role of exercise in neuromuscular disease (NMD). We demonstrate that despite the different pathologies in NMDs, exercise is beneficial, whether aerobic/endurance or strength/resistive training, and we explore whether this benefit has a similar mechanism to that of healthy subjects. We discuss further areas for study, incorporating imaginative and novel approaches to training and its assessment in NMD. We conclude by suggesting ways to improve future trials by avoiding previous methodological flaws and drawbacks in this field.
authors.affiliation: Department of Neurology, SUNY-Downstate Medical Center, 450 Clarkson Avenue, Box 1213, Brooklyn, New York, 11203, USA. yanziska@downstate.edu
authors.forename: Yaacov
authors.initials: Y
authors.lastname: Anziska
authors.forename: Alex
authors.initials: A
authors.lastname: Sternberg
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic / Q000379:methods; D015444:Exercise / Q000502:physiology*; D005081:Exercise Therapy / Q000379:methods*; D006801:Humans; D053580:Muscle Strength / Q000502:physiology*; D009468:Neuromuscular Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D010807:Physical Endurance / Q000502:physiology; D055070:Resistance Training / Q000379:methods*