title: Human immunodeficiency virus-associated lung malignancies.
abstract: This review of lung malignancies in human immunodeficiency virus (HIV) briefly highlights key epidemiologic and clinical features in the pulmonary involvement of AIDS-defining malignancies of Kaposi sarcoma and non-Hodgkin lymphoma. Then, focusing on non-AIDS defining lung cancer, the epidemiology and mechanisms, clinical presentation, pathology, treatment and outcomes, and prevention of HIV-associated lung cancer are discussed. Finally, the important knowledge gaps and future directions for research related to HIV-associated lung malignancies are highlighted.
authors.affiliation: Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
authors.forename: Allison A
authors.initials: AA
authors.lastname: Lambert
authors.forename: Christian A
authors.initials: CA
authors.lastname: Merlo
authors.forename: Gregory D
authors.initials: GD
authors.lastname: Kirk
mesh_terms: D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D016483:Lymphoma, AIDS-Related / Q000453:epidemiology / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000453:epidemiology / Q000628:therapy / Q000821:virology; D012514:Sarcoma, Kaposi / Q000453:epidemiology / Q000628:therapy / Q000821:virology; D012907:Smoking / Q000009:adverse effects