title: HPV-based Tests for Cervical Cancer Screening and Management of Cervical Disease.
abstract: Current cervical cancer screening programs are changing due to the development of tests that detect the presence of human papillomavirus (HPV), the cause of cervical cancer. These tests are more sensitive than cytology-based methods for detecting cervical precancer and a negative test offers long-term assurance that cervical cancer will not develop and therefore longer screening intervals can be achieved. In screening programs, HPV-based tests have been approved to triage women with equivocal cytology results and as a primary testing method in conjunction with cytology. HPV-based tests also have a role in determining risk of recurrence after treatment for cervical precancer as well as in surveillance for vaccine-related changes in HPV genotype prevalence.
authors.affiliation: Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD ; Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Rockville, MD.
authors.forename: Patricia
authors.initials: P
authors.lastname: Luhn
authors.forename: Nicolas
authors.initials: N
authors.lastname: Wentzensen
keywords: HPV; cervical cancer; cervical precancer; management of HPV; prevention; screening; screening programs