title: [Iliofemoral cutaneous mucormycosis with endopelvic extension in an immunocompetent child].
abstract: Mucormycosis is a rare opportunistic fungal infection with clinical polymorphism and is rapidly extensive and destructive. It is caused by fungi of the mucorales group in the environment and generally arises in the context of immunosuppression. Often difficult and late, diagnosis is based on mycological and histological examination. We report the case of a 10-year-old patient admitted for a pruritic erythematous scaly eruption located in the right inguinal area associated with satellite lymphadenopathy and lymphedema of the right lower limb. The histological study of the cutaneous biopsy revealed a granulomatous reaction with filaments. The mycological examination of the collection of the cutaneous lesion showed mucorales filaments and a stump of Absidia corymbifera was isolated. Abdomino-pelvic CT showed muscular extension with vascular and ureteral englobement. The diagnosis of cutaneous mucormycosis was made. Immunological investigations were normal. Treatment included itraconazole for 3months followed by IV amphotericin B for 1month, with favorable clinical and radiological progression. Mucormycosis is an uncommon fungal infection whose cutaneous localization is rare. It occurs exceptionally in immunocompetent patients and is clinically manifested by a vesicular and pustular rash progressing to ulceration. The diagnosis is confirmed by mycological and histological studies. Treatment consists of antifungal therapy associated with surgical excision of necrotic and infected tissue.
authors.affiliation: Service de pédiatrie IV, faculté de médecine et pharmacie, université Mohammed V-Souissi, hôpital d'enfants, avenue Belarbi El Alaoui, BP 6203, Rabat, Maroc. elguazzarsanaa@gmail.com
authors.forename: S
authors.initials: S
authors.lastname: Elguazzar
authors.forename: T
authors.initials: T
authors.lastname: Benouachane
authors.forename: A
authors.initials: A
authors.lastname: Nasri
authors.forename: A
authors.initials: A
authors.lastname: Malihy
authors.forename: H
authors.initials: H
authors.lastname: Tligui
authors.forename: A
authors.initials: A
authors.lastname: Bentahila
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002648:Child; D003881:Dermatomycoses / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D004890:Erythema / Q000382:microbiology; D006099:Granuloma / Q000473:pathology; D006119:Groin; D006801:Humans; D007121:Immunocompetence; D017964:Itraconazole / Q000627:therapeutic use; D008209:Lymphedema / Q000382:microbiology; D008297:Male; D009091:Mucormycosis / Q000175:diagnosis* / Q000188:drug therapy; D011537:Pruritus / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B