title: [Thrombotic thrombocytopenic purpura: do not ignore cardiac involvement].
abstract: BACKGROUND
  Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy due to ADAMTS13 deficiency (a von Willebrand factor's metalloprotease) with multiple organs' involvement, one of which may be the heart.
  
  
  METHODS
  We report a 29-year-old woman who presented a TTP during her last trimester of pregnancy, under the features of a HELLP syndrome. After caesarean section, cardiac involvement was revealed by chest pain, ECG changes, antero-septal hypokinesia and troponin rise. Cardiac MRI found no large-vessel ischemic heart disease and confirmed hypokinesia.
  
  
  CONCLUSIONS
  When TTP is diagnosed, cardiac involvement must be systematically investigated by ECG and troponin assay because of the risk of a cardiac arrest.
authors.affiliation: Service de réanimation médicale et médecine interne, hôpital Jean-Bernard, centre hospitalier universitaire de Poitiers, BP 577, 2, rue de la Milétrie, 86021 Poitiers cedex, France. Electronic address: mathieu.puyade@sfr.fr.
authors.forename: M
authors.initials: M
authors.lastname: Puyade
authors.affiliation: Service de réanimation médicale et médecine interne, hôpital Jean-Bernard, centre hospitalier universitaire de Poitiers, BP 577, 2, rue de la Milétrie, 86021 Poitiers cedex, France.
authors.forename: J
authors.initials: J
authors.lastname: Badin
authors.affiliation: Service de réanimation médicale et médecine interne, hôpital Jean-Bernard, centre hospitalier universitaire de Poitiers, BP 577, 2, rue de la Milétrie, 86021 Poitiers cedex, France.
authors.forename: B
authors.initials: B
authors.lastname: Quéron
authors.affiliation: Service de cardiologie, centre hospitalier universitaire de Poitiers, 2, rue de la Milétrie, 86021 Poitiers cedex, France.
authors.forename: L
authors.initials: L
authors.lastname: Christiaens
authors.affiliation: Service de cardiologie, centre hospitalier universitaire de Poitiers, 2, rue de la Milétrie, 86021 Poitiers cedex, France.
authors.forename: N
authors.initials: N
authors.lastname: Varroud-Vial
authors.affiliation: Service de gynécologie obstétrique, centre hospitalier universitaire de Poitiers, 2, rue de la Milétrie, 86021 Poitiers cedex, France.
authors.forename: F
authors.initials: F
authors.lastname: Pierre
authors.affiliation: Service de réanimation médicale et médecine interne, hôpital Jean-Bernard, centre hospitalier universitaire de Poitiers, BP 577, 2, rue de la Milétrie, 86021 Poitiers cedex, France.
authors.forename: O
authors.initials: O
authors.lastname: Pourrat
mesh_terms: D000328:Adult; D005260:Female; D017359:HELLP Syndrome / Q000175:diagnosis / Q000209:etiology; D006331:Heart Diseases / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis* / Q000209:etiology*; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000150:complications* / Q000175:diagnosis*
keywords: Arrêt cardiaque; Cardiac arrest; Cœur; Heart; Purpura thrombotique thrombocytopénique; Thrombotic thrombocytopenic purpura; Troponin; Troponine