title: New approach to oximes through reduction of nitro compounds enabled by visible light photoredox catalysis.
abstract: A range of nitro compounds are smoothly reduced to their corresponding oximes under the synergistic effects of visible light irradiation, the Ru(bpy)3Cl2 photocatalyst, Hünig's base, Mg(ClO4)2 activation, and MeCN solvent. This remarkably mild and environmentally benign protocol, when orchestrated with classical Beckmann rearrangement, enables such high-value industrial feedstock as caprolactam to be readily accessed from simple precursor nitrocyclohexane.
authors.affiliation: Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China 518055.
authors.forename: Shunyou
authors.initials: S
authors.lastname: Cai
authors.forename: Shaolong
authors.initials: S
authors.lastname: Zhang
authors.forename: Yaohong
authors.initials: Y
authors.lastname: Zhao
authors.forename: David Zhigang
authors.initials: DZ
authors.lastname: Wang
mesh_terms: D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry*; D008027:Light; D017616:Magnesium Compounds / Q000737:chemistry; D015394:Molecular Structure; D009574:Nitro Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D010091:Oximes / Q000138:chemical synthesis* / Q000737:chemistry; D010472:Perchlorates / Q000737:chemistry; D055668:Photochemical Processes; D012428:Ruthenium / Q000737:chemistry
chemical_list: D056831:Coordination Complexes; D017616:Magnesium Compounds; D009574:Nitro Compounds; D010091:Oximes; D010472:Perchlorates; C016547:magnesium perchlorate; D012428:Ruthenium