title: Imaging spectrum and pitfalls of ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with tuberculosis.
abstract: Mycobacterium tuberculosis (TB) is one of the most prominant diseases frequently causing false positive lesions in oncologic surveys using (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT), since TB granulomas are composed of activated macrophages and lymphocytes with high affinity for glucose. These pitfalls of (18)F-FDG PET/CT are important for radiologists. Being familiar with (18)F-FDG images of TB could assist in preventing unfavorable clinical results based on misdiagnoses. In addition, (18)F-FDG PET/CT has the advantage of being able to screen the whole body, and can clearly detect harboring TB lesions as high uptake foci. This article details the spectrum and pitfalls of (18)F-FDG PET/CT imaging in TB.
authors.affiliation: Department of Radiology, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira, Tokyo 187-8551, Japan. itoukimiteru@yahoo.co.jp
authors.forename: Kimiteru
authors.initials: K
authors.lastname: Ito
authors.forename: Miyako
authors.initials: M
authors.lastname: Morooka
authors.forename: Ryogo
authors.initials: R
authors.lastname: Minamimoto
authors.forename: Yoko
authors.initials: Y
authors.lastname: Miyata
authors.forename: Momoko
authors.initials: M
authors.lastname: Okasaki
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kubota
mesh_terms: D019788:Fluorodeoxyglucose F18; D006801:Humans; D064847:Multimodal Imaging / Q000379:methods*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014376:Tuberculosis / Q000175:diagnosis*; D051598:Whole Body Imaging / Q000379:methods
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18