title: Seroma suppression using TissuGlu® in a high-risk patient post-mastectomy: a case report.
abstract: BACKGROUND
  Post-mastectomy seromas are a common problem in modern oncological surgery. Occurrence rates of up to 59% have been reported in the literature. High-risk patients, that is, those who have received previous surgeries, radiation or chemotherapy, present a particular challenge. Several surgical techniques, including progressive tension suture application, have shown promise. Noninvasive measures such as fibrin-based adhesives have thus far not been able to prevent seroma occurrence effectively. A recent study using a lysine-derived urethane adhesive named TissuGlu®, however, showed promising results in patients after abdominoplasty.
  
  
  METHODS
  We used TissuGlu® to treat a high-risk 64-year-old female patient with a history of breast cancer and severe post-mastectomy seroma. The postsurgical period showed successful seroma suppression, without any adverse effects or complications.
  
  
  CONCLUSIONS
  This type of adhesive should be evaluated as an alternative, less-invasive option for preventing seroma in patients after a mastectomy.
authors.affiliation: Department of Gynecology and Obstetrics, Holweide Hospital, Cologne, Germany. ceichler@gmail.com.
authors.forename: Christian
authors.initials: C
authors.lastname: Eichler
authors.forename: Faten
authors.initials: F
authors.lastname: Dahdouh
authors.forename: Axel
authors.initials: A
authors.lastname: Sauerwald
authors.forename: Mathias
authors.initials: M
authors.lastname: Warm