title: Biopolymer coated gold nanocrystals prepared using the green chemistry approach and their shape-dependent catalytic and surface-enhanced Raman scattering properties.
abstract: This study deals with the preparation of multi-shaped nanoscale gold crystals under synthetically simple, green, and efficient conditions using a seed-mediated growth approach in the presence of hyaluronic acid (HA). These highly biocompatible multi-shaped gold nanocrystals were examined to evaluate their catalytic and surface enhanced Raman scattering (SERS) properties. The results show that the size and shape of the nanocrystals are mainly correlated to the amount of seed, seed size, HA concentration, and reaction temperature. Gold seeds accelerate the reduction of the gold precursor to form gold nanocrystals using HA. The HA serves as a reducing agent and a growth template for the reduction of Au(III) and nanocrystal stabilization. The multi-shaped gold nanocrystals showed superior catalytic properties and higher SERS performance. The simple, green approach efficiently controls the nanocrystals and creates many opportunities for future applications.
authors.affiliation: Department of Cosmeceutics, China Medical University, No. 91, Hsueh-Shih Rd., Taichung 40402, Taiwan. cwchou@mail.cmu.edu.tw
authors.forename: Chih-Wei
authors.initials: CW
authors.lastname: Chou
authors.forename: Hui-Hsuan
authors.initials: HH
authors.lastname: Hsieh
authors.forename: You-Cheng
authors.initials: YC
authors.lastname: Hseu
authors.forename: Ko-Shao
authors.initials: KS
authors.lastname: Chen
authors.forename: Gou-Jen
authors.initials: GJ
authors.lastname: Wang
authors.forename: Hsien-Chang
authors.initials: HC
authors.lastname: Chang
authors.forename: Yong-Li
authors.initials: YL
authors.lastname: Pan
authors.forename: Yi-Syuan
authors.initials: YS
authors.lastname: Wei
authors.forename: Ko Hsin
authors.initials: KH
authors.lastname: Chang
authors.forename: Yeu-Wei
authors.initials: YW
authors.lastname: Harn
mesh_terms: D001704:Biopolymers / Q000737:chemistry*; D002384:Catalysis; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D055772:Green Chemistry Technology; D006820:Hyaluronic Acid / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D013059:Spectrum Analysis, Raman; D013499:Surface Properties
chemical_list: D001704:Biopolymers; D020099:Coated Materials, Biocompatible; D006046:Gold; D006820:Hyaluronic Acid