title: [Thrombosis of the pelvic and leg--conservative procedure or thrombolytic therapy?].
abstract: METHODS
  We report on a young female patient with flank pain and a swelling of the lower limb of the left side.
  
  
  METHODS
  In magnetic resonance angiography as well as Doppler-duplex ultrasound an iliofemoral phlebothrombosis of the left side due to vena cava inferior hypoplasia with collateral circulation was diagnosed. Oral contraception could play a role as a trigger. The patient also presented activated protein C resistance/ heterozygous factor V Leiden mutation.
  
  
  METHODS
  According to the CaVenT study we treated the patient successfully with catheter-directed thrombolysis. Follow-ups presented a patency of the iliofemoral vein.
  
  
  CONCLUSIONS
  In young patients with short duration of a proximal deep vein thrombosis and after exclusion of contraindications a catheter-directed lysis should be considered as a treatment option. The differential diagnostic of a (bilateral) ilio-femoral vein thrombosis in young patients should include an anomaly of the venous system.
authors.affiliation: Medizinische Klinik-Endokrinologie und Diabetologie, Angiologie, Nephrologie und Klinische Chemie, Universitätsklinikum Tübingen. elko.randrianarisoa@med.uni-tuebingen.de
authors.forename: Elko
authors.initials: E
authors.lastname: Randrianarisoa
authors.forename: Kilian
authors.initials: K
authors.lastname: Rittig
authors.forename: Klaus
authors.initials: K
authors.lastname: Brechtel
authors.forename: Winfried
authors.initials: W
authors.lastname: Baden
authors.forename: Ferruh
authors.initials: F
authors.lastname: Artunc
authors.forename: Bernd
authors.initials: B
authors.lastname: Balletshofer
mesh_terms: D000328:Adult; D003276:Contraceptives, Oral / Q000009:adverse effects; D004252:DNA Mutational Analysis; D005165:Factor V / Q000235:genetics; D005260:Female; D005268:Femoral Vein; D006580:Genetic Carrier Screening; D006801:Humans; D007084:Iliac Vein; D018810:Magnetic Resonance Angiography; D012307:Risk Factors; D015912:Thrombolytic Therapy; D018616:Ultrasonography, Doppler, Duplex; D014682:Vena Cava, Inferior / Q000002:abnormalities*; D020246:Venous Thrombosis / Q000188:drug therapy* / Q000235:genetics
chemical_list: D003276:Contraceptives, Oral; C095381:factor V Leiden; D005165:Factor V