title: A chiral ruthenium-monophosphine catalyst for asymmetric addition of arylboronic acids to aryl aldehydes.
abstract: A novel ruthenium catalyst on the basis of a chiral monophosphorus ligand is efficient for the asymmetric addition of arylboronic acids to aryl aldehydes, providing a series of chiral diarylmethanols in excellent yields and enantioselectivities (up to 92% ee). Preliminary study has shown that this process is catalyzed by a Ru complex with a single monophosphorus ligand.
authors.affiliation: Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Li
authors.forename: Naifu
authors.initials: N
authors.lastname: Hu
authors.forename: Renshi
authors.initials: R
authors.lastname: Luo
authors.forename: Weicheng
authors.initials: W
authors.lastname: Yuan
authors.forename: Wenjun
authors.initials: W
authors.lastname: Tang
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D010720:Phosphines / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D001897:Boronic Acids; D010720:Phosphines; D012428:Ruthenium