title: Sleep quality moderates the relation between depression symptoms and problematic cannabis use among medical cannabis users.
abstract: OBJECTIVE
  This study sought to extend research on the relation between depression symptoms and problematic cannabis use by evaluating the potential moderating role of perceived sleep quality among medical cannabis users.
  
  
  METHODS
  This employed a cross-sectional design. The sample consisted of 162 adults (mean age = 42.05 years, SD = 14.8; 22% female), with current recommendations from a doctor for medical cannabis, recruited from a medical cannabis dispensary.
  
  
  RESULTS
  Consistent with previous research, individuals with heightened depression symptoms had greater problematic cannabis use. In addition, perceived sleep quality moderated this relation, such that depression symptoms differentially related to problematic cannabis use as a function of perceived quality of sleep (ΔR(2) = .03, p = .02). Participants with higher levels of depression and good perceived sleep quality had the greatest rates of problematic cannabis use.
  
  
  CONCLUSIONS
  These results suggest that individuals with heightened depression may have higher rates of problematic cannabis use, in part, because of the beneficial effects of cannabis in terms of perceived sleep quality.
authors.affiliation: Center for Health Care Evaluation, VA Palo Alto Health Care System, Menlo Park, CA 94025, USA. Kimberly.Babson@va.gov
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Babson
authors.forename: Matthew Tyler
authors.initials: MT
authors.lastname: Boden
authors.forename: Marcel O
authors.initials: MO
authors.lastname: Bonn-Miller
mesh_terms: D000328:Adult; D002188:Cannabis; D003863:Depression; D003866:Depressive Disorder; D005260:Female; D006801:Humans; D008297:Male; D002189:Marijuana Abuse; D008875:Middle Aged; D012044:Regression Analysis; D012890:Sleep; D007319:Sleep Initiation and Maintenance Disorders