title: [Effect of kardostin on the generative function of female rats].
abstract: The effects of kardostin on the ovulatory cycle, conception, and sexual behavior of female rats have been experimentally studied. It is established that a two-week therapy with kardostin at a dose of 5 and 15 mg/kg changed phases of the estrous cycle (with the estrus phase being most prevalent) and led to ambiguous changes in the sexual behavior of female rats (a dose of 5 mg/kg increased sexual behavior, while a dose of 15 mg/kg inhibited it), activated fertility, and improved the quality of conception.
authors.forename: E B
authors.initials: EB
authors.lastname: Lavrova
authors.forename: E A
authors.initials: EA
authors.lastname: Kuzubova
authors.forename: L I
authors.initials: LI
authors.lastname: Bugaeva
authors.forename: V I
authors.initials: VI
authors.lastname: Petrov
authors.forename: I A
authors.initials: IA
authors.lastname: Kheĭfets
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Dugina
authors.forename: O I
authors.initials: OI
authors.lastname: Épshteĭn
mesh_terms: D057912:Angiotensin II Type 2 Receptor Blockers / Q000494:pharmacology*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D030762:Estrous Cycle / Q000187:drug effects; D005260:Female; D005298:Fertility / Q000187:drug effects*; D005306:Fertilization / Q000187:drug effects*; D008297:Male; D008597:Menstrual Cycle / Q000187:drug effects; D052250:Nitric Oxide Synthase Type III / Q000037:antagonists & inhibitors / Q000378:metabolism; D011247:Pregnancy; D051381:Rats; D044139:Receptor, Angiotensin, Type 2 / Q000378:metabolism; D012726:Sexual Behavior, Animal / Q000187:drug effects*
chemical_list: D057912:Angiotensin II Type 2 Receptor Blockers; D000911:Antibodies, Monoclonal; D044139:Receptor, Angiotensin, Type 2; D052250:Nitric Oxide Synthase Type III; C496316:Nos3 protein, rat