title: Management of bleb complications after trabeculectomy.
abstract: Trabeculectomy remains a mainstay surgery for glaucoma. The necessity to raise a bleb and use of chemoadjuvants may result in bleb-related complications, such as bleb-fibrosis, bleb-leaks, bleb-related infections, overfiltration, or hypotony. This review highlights some of the latest developments in preventing and managing these complications, including anti-vascular endothelial growth factors, monoclonal antibodies for moderate reduction of fibrosis, newer surgical strategies for bleb leaks, an update from a randomized clinical trial highlighting the incidence and management of bleb-related infections, and various treatment strategies for an overfiltering bleb. In addition, other surgical interventions with less or no bleb-related complications will be discussed, including non-penetrating glaucoma surgeries, glaucoma drainage devices, or phacoemulsification.
authors.affiliation: Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong, The People's Republic of China. dexleung@alumni.cuhk.net
authors.forename: Dexter Y L
authors.initials: DY
authors.lastname: Leung
authors.forename: Clement C Y
authors.initials: CC
authors.lastname: Tham
mesh_terms: D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications / Q000628:therapy*; D019738:Surgically-Created Structures / Q000009:adverse effects*; D014129:Trabecular Meshwork / Q000601:surgery; D014130:Trabeculectomy