title: Prevalence and clinical characteristics of patients with obsessive-compulsive disorder in first-episode psychosis.
abstract: BACKGROUND
  Obsessive-compulsive disorder (OCD) in patients with psychotic disorders has been reported to be a frequent co-morbid disorder in patients with psychotic disorders. The aim of the study determine the prevalence of OCD in first-episode psychosis and the relationship with clinical characteristics.
  
  
  METHODS
  First-episode psychosis patients (N = 246) consecutively admitted to a comprehensive early psychosis program were assessed for OCD with the Structured Clinical Interview for DSM-IV. Symptom assessment measures were the Positive and Negative Syndrome Scale, Global Assessment of Functioning, and the Clinician Rating Scale.
  
  
  RESULTS
  Twenty-six patients (10.6%) fulfilled the criteria for OCD. Patients with comorbid OCD were younger, had more depressive symptoms and a higher rate of suicidal plans or attempts at index point compared to patients without OCD. The two groups did not differ with respect to other demographic variables or severity of psychotic symptoms.
  
  
  CONCLUSIONS
  OCD is a significant comorbid disorder in patients with first-episode psychosis. Since treatment procedures are different, systematic screening for OCD is warranted.
authors.affiliation: Østmarka Psychiatric Department, St. Olav's University Hospital, Trondheim 7441, Norway. kristeha@stud.ntnu.no
authors.forename: Kristen
authors.initials: K
authors.lastname: Hagen
authors.forename: Bjarne
authors.initials: B
authors.lastname: Hansen
authors.forename: Inge
authors.initials: I
authors.lastname: Joa
authors.forename: Tor Ketil
authors.initials: TK
authors.lastname: Larsen
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D000368:Aged; D015897:Comorbidity; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D015995:Prevalence; D011618:Psychotic Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D012559:Schizophrenia / Q000175:diagnosis / Q000453:epidemiology*; D012565:Schizophrenic Psychology; D012720:Severity of Illness Index; D059020:Suicidal Ideation; D013406:Suicide, Attempted / Q000523:psychology