title: A preliminary analysis of the data from an in vitro inflation-extension test can validate the assumption of arterial tissue elasticity.
abstract: The objective of this study is to propose a method for preliminary processing of the experimental data from an inflation-extension test on tubular arterial specimens. The method is based on the condition for existence of a strain energy function (SEF) and can be used to verify whether the data from a certain experiment validate the assumption that the tissue can be considered as an elastic solid. As an illustrative example of the proposed method, experimental data for a porcine renal artery are used and the sources of the error in satisfying the condition of elasticity are analyzed. The results lead to the conclusion that the experimental data for a renal artery validate that the artery exhibits an elastic mechanical response and a constitutive formulation based on the existence of the SEF is justified. A modification of the proposed method for the case of an in-plane biaxial stretching test of mechanically isotropic and orthotropic tissues is considered.
authors.affiliation: College of Engineering and Computing, Biomedical Engineering Program, University of South Carolina, Columbia, SC 29208, USA. a.i.rachev@gmail.com
authors.forename: Alexander
authors.initials: A
authors.lastname: Rachev
authors.forename: Tarek
authors.initials: T
authors.lastname: Shazly
mesh_terms: D000818:Animals; D001158:Arteries / Q000033:anatomy & histology / Q000502:physiology*; D001696:Biomechanical Phenomena; D001698:Biomedical Engineering; D004548:Elasticity; D006439:Hemodynamics; D008955:Models, Cardiovascular; D012077:Renal Artery / Q000033:anatomy & histology / Q000502:physiology; D013314:Stress, Mechanical; D013552:Swine