title: Cranial vault growth in multiple-suture nonsyndromic and syndromic craniosynostosis: a postoperative long-term anthropometric follow-up.
abstract: Long-term anthropometric follow-up of cranial vault growth may considerably add valuable information to current literature focusing on treatment strategies for premature multiple-suture craniosynostosis. The aim of this paper was to compare postoperative growth patterns of nonsyndromic and syndromic multiple-suture craniosynostotic children with sex-matched and age-matched children from the typically developing population. Forty-one multiple-suture craniosynostotic patients (19 nonsyndromic and 22 syndromic) were included in this 5-year follow-up. Anthropological data of sex-matched and age-matched normal Swiss children served as a control. A standardized time protocol for anthropometric skull measurements (head circumference and cephalic index) was used. Data were converted into Z-scores for standardized intercenter comparison. All patients showed a marked benefit in cranial vault shape after open skull remodeling. Significant differences in long-term cranial vault growth pattern could be seen between the nonsyndromic and the syndromic groups compared to the control group.
authors.affiliation: Department of Cranio-Maxillofacial and Oral Surgery, University of Zurich, Zurich, Switzerland. Philipp.Metzler@usz.ch
authors.forename: Philipp
authors.initials: P
authors.lastname: Metzler
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Zemann
authors.forename: Christine
authors.initials: C
authors.lastname: Jacobsen
authors.forename: Heinz-Theo
authors.initials: HT
authors.lastname: Lübbers
authors.forename: Klaus Wilhelm
authors.initials: KW
authors.lastname: Grätz
authors.forename: Joachim Anton
authors.initials: JA
authors.lastname: Obwegeser
mesh_terms: D000168:Acrocephalosyndactylia / Q000503:physiopathology / Q000601:surgery; D016022:Case-Control Studies; D002508:Cephalometry / Q000379:methods*; D003393:Cranial Sutures / Q000254:growth & development / Q000601:surgery; D003394:Craniofacial Dysostosis / Q000503:physiopathology / Q000601:surgery; D003398:Craniosynostoses / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D011884:Radius / Q000002:abnormalities / Q000503:physiopathology / Q000601:surgery; D012189:Retrospective Studies; D012886:Skull / Q000254:growth & development* / Q000601:surgery