title: Anti-cancer mechanism and possibility of nano-suspension formulations for a marine algae product fucoxanthin.
abstract: Recently, use of natural products available from marine sources, and especially algae products, are receiving more attention. Scientific evidence for claimed nutraceutical and therapeutical effects of one such marine algae product, fucoxanthin, is discussed in this paper with a summary of the currently available literature regarding its antioxidant, anti-obesity and anticancer activities. It is safe for use in humans, but as it has poor solubility a nano-suspension mode of delivery may be adopted to improve efficacy of supplements. We conclude from our literature review that the marine algae product fucoxanthin has significant antioxidant, anti-obesity and anticancer activity with established mechanisms of action.
authors.affiliation: Medicinal Chemistry and Nanoscience Research Laboratory, Centre for Research and Development, PRIST University, Thanjavur, Tamilnadu, India. sriniclic@gmail.com
authors.forename: Srinivasan
authors.initials: S
authors.lastname: Muthuirulappan
authors.forename: Steffi Pulikodan
authors.initials: SP
authors.lastname: Francis
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D016503:Drug Delivery Systems; D006801:Humans; D008386:Marine Biology; D053758:Nanoparticles / Q000737:chemistry*; D009369:Neoplasms / Q000188:drug therapy*; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D000461:Rhodophyta / Q000378:metabolism*; D013535:Suspensions; D024341:Xanthophylls / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D004364:Pharmaceutical Preparations; D013535:Suspensions; D024341:Xanthophylls; C025164:fucoxanthin