title: Comparision of vacuum-asisted closure and moist wound dressing in the treatment of diabetic foot ulcers.
abstract: BACKGROUND
  Vacuum-assisted closure (VAC) is a new method in wound care which speeds wound healing by causing vacuum, improving tissue perfusion and suctioning the exudates. This study aims to evaluate its efficacy in the treatment of diabetic foot ulcers.
  
  
  METHODS
  Thirteen patients with diabetic foot ulcers were enrolled in the moist dressing group, and 10 patients in the VAC group. The site, size and depth of the wound were inspected and recorded before and every three days during the study period. Patient satisfaction and formation of granulation tissue were also assessed.
  
  
  RESULTS
  Improvement of the wound in the form of reducing the diameter and depth and increasing proliferation of granulation tissue was significant in most of the patients of the VAC group after two weeks. Satisfaction of patients in the VAC group was evaluated as excellent as no amputation was done in this group. Wagner score was reduced in both the study groups, although this decrement was not significant in the moist dressing group.
  
  
  CONCLUSIONS
  VAC appears to be as safe as and more efficacious than moist dressing for the treatment of diabetic foot ulcers.
authors.affiliation: Vascular and Endovascular Surgery Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Hassan
authors.initials: H
authors.lastname: Ravari
authors.forename: Mohammad-Hadi Saeed
authors.initials: MH
authors.lastname: Modaghegh
authors.forename: Gholam Hosein
authors.initials: GH
authors.lastname: Kazemzadeh
authors.forename: Hamed Ghoddusi
authors.initials: HG
authors.lastname: Johari
authors.forename: Attieh Mohammadzadeh
authors.initials: AM
authors.lastname: Vatanchi
authors.forename: Abolghasem
authors.initials: A
authors.lastname: Sangaki
authors.forename: Mohammad Vahedian
authors.initials: MV
authors.lastname: Shahrodi
keywords: Diabetic foot ulcers; moist wound dressing; vacuum-assisted closure; wound therapy