title: Aptamer-functionalized hydrogel diffraction gratings for the human thrombin detection.
abstract: The aptamer-functionalized hydrogel diffraction gratings were successfully fabricated by incorporating an aptamer and its complementary sequence as crosslinking junctions in the network structure. The gratings showed a sensitive response to human thrombin as read out from the diffracted light.
authors.affiliation: Department of Chemical Engineering, Laboratory of Advanced Materials (MOE), Tsinghua University, Beijing, PR China.
authors.forename: Xiaoqi
authors.initials: X
authors.lastname: Wang
authors.forename: Xiaogong
authors.initials: X
authors.lastname: Wang
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques; D006801:Humans; D020100:Hydrogels / Q000737:chemistry*; D055096:Optical Devices; D013917:Thrombin / Q000032:analysis* / Q000737:chemistry
chemical_list: D052157:Aptamers, Nucleotide; D020100:Hydrogels; D013917:Thrombin