title: Differences in distribution and antimicrobial susceptibility of anaerobes isolated from complicated intra-abdominal infections versus diabetic foot infections.
abstract: Few labs isolate and perform susceptibility tests on anaerobes; therefore, we studied the differences between 1185 anaerobes isolated from complicated intra-abdominal infections and 470 isolated from moderate to severe diabetic foot infections. They differed markedly in the distribution of species, including Bacteroides fragilis and anaerobic Gram-positive cocci, as well as in resistance patterns, especially to fluoroquinolones.
authors.affiliation: Roche Diagnostics International AG, Rotkreuz, Switzerland.
authors.forename: Marina
authors.initials: M
authors.lastname: Claros
authors.forename: Diane M
authors.initials: DM
authors.lastname: Citron
authors.forename: Ellie J C
authors.initials: EJ
authors.lastname: Goldstein
authors.forename: C Vreni
authors.initials: CV
authors.lastname: Merriam
authors.forename: Kerin L
authors.initials: KL
authors.lastname: Tyrrell
mesh_terms: D000693:Anaerobiosis; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001442:Bacteroides Infections / Q000188:drug therapy / Q000382:microbiology; D001441:Bacteroides fragilis / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D017719:Diabetic Foot / Q000188:drug therapy / Q000382:microbiology; D024881:Drug Resistance, Bacterial / Q000502:physiology*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D006095:Gram-Positive Cocci / Q000145:classification / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D006801:Humans; D059413:Intraabdominal Infections / Q000188:drug therapy / Q000382:microbiology; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents
keywords: Anaerobes, Diabetic foot infection; Bacteroides fragilis; Ertapenem; Finegoldia magna; Intra-abdominal infection; Levofloxacin; Resistance