title: Hepatitis C virus infection: looking for interferon free regimens.
abstract: Recent developments of new drugs' combinations are changing the treatment paradigm in hepatitis C virus infection. Due to the side effect profile of pegylated interferons, interferon-sparing regimens have become the main target in chronic hepatitis C treatment research. Recent proofs of concept studies have suggested that cure of chronic hepatitis C can be achieved without interferon. The purpose of this paper is to provide an overview of the clinical results recently reported for the treatment of hepatitis C virus infection with interferon-free regimens, focusing on the most promising new compounds and combinations.
authors.affiliation: Internal Medicine-Infectious Diseases Department, Hospital Son Llàtzer, Carretera de Manacor, Km 4, 07198 Palma de Mallorca, Spain. jgonzalez4@hsll.es
authors.forename: J
authors.initials: J
authors.lastname: González-Moreno
authors.forename: A
authors.initials: A
authors.lastname: Payeras-Cifre
mesh_terms: D000998:Antiviral Agents / Q000008:administration & dosage* / Q000145:classification*; D006526:Hepatitis C / Q000188:drug therapy*; D006801:Humans; D007372:Interferons / Q000009:adverse effects / Q000627:therapeutic use*; D011480:Protease Inhibitors / Q000627:therapeutic use*
chemical_list: D000998:Antiviral Agents; D011480:Protease Inhibitors; D007372:Interferons