title: [Development of the mastoid air cells and its relationship to Ménière's disease].
abstract: OBJECTIVE
  To investigate the fundamental pathological anatomy and possible pathogenetic factors of Ménière's disease(MD), we compared the types of mastoid air cells between the MD group and the control group.
  
  
  METHODS
  The MD group had 113 ears and the control group had 100 ears. Temoral bone CT scanning was performed in all the subjects. The types of mastoid air cells were determined by surgical findings and imaging data. All the mastoid air cells were divided into diploetic type, gasified type and sclerosis type. Analysis of the proportion of different types and the statistical analysis were performed between the two groups.
  
  
  RESULTS
  51.4% (57/113) in the MD group and 18.0% (18/100) in the control group were diploetic type mastoid, the difference was significant (χ(2) = 24.476, P < 0.001). The gasified type was 43.4% (49/113) in the MD group and 77.0% (77/100) in the control group, the difference was significant (χ(2) = 24.843, P < 0.001). The sclerosis type was 6.2% in the MD group and 5.0% (5/100) in the control group, and there was no statistical significance (χ(2) = 0.142,P > 0.05).
  
  
  CONCLUSIONS
  The mastoid air cells are dysplasia in MD patients, and it may be one of the fundamental pathological anatomy. The long-term ventilation and drainage disorder and recurrent inflammation attack may play an important role in occurrence, development and prognosis of MD.
authors.affiliation: Department of Otorhinolaryngology, People's Hospital of Peking University, Beijing 100044, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Han
authors.forename: Yuan-yuan
authors.initials: YY
authors.lastname: Jing
authors.forename: Li-sheng
authors.initials: LS
authors.lastname: Yu
authors.forename: Rui-ming
authors.initials: RM
authors.lastname: Xia
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D004712:Endolymphatic Sac / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008416:Mastoid / Q000473:pathology*; D008575:Meniere Disease / Q000473:pathology*; D008875:Middle Aged; D055815:Young Adult