title: Chapter 11: Granulomatous diseases and chronic sinusitis.
abstract: Nasal crusting, rhinitis, and sinusitis are presentations of common conditions; however, these can also be the presenting symptoms of an underlying systemic disorder such as an infection, malignancy, or granulomatous disease. Granulomatous diseases with head and neck manifestations include Wegener's granulomatosis, Churg-Strauss syndrome, and sarcoidosis. These diseases are managed through a multidisciplinary approach that often includes otolaryngologists. This article presents a brief review of granulomatous diseases and their rhinologic manifestations and includes relevant diagnostic tests and systemic and local treatment options.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins Sinus Center, Baltimore, Maryland 21287, USA.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Kohanski
authors.forename: Douglas D
authors.initials: DD
authors.lastname: Reh
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000818:Animals; D002908:Chronic Disease; D015267:Churg-Strauss Syndrome / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D003955:Diagnostic Tests, Routine; D004724:Endoscopy; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D006801:Humans; D010256:Paranasal Sinuses / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011859:Radiography; D012220:Rhinitis / Q000276:immunology*; D012507:Sarcoidosis / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D012852:Sinusitis / Q000276:immunology*
chemical_list: D000305:Adrenal Cortex Hormones; D003520:Cyclophosphamide