title: ExtremeDB: a unified web repository of extremophilic archaea and bacteria.
abstract: Extremophiles are the microorganisms which can survive under extreme conditions of temperature, pressure, pH, salinity etc. They have gained much attention for their potential role in biotechnological and industrial applications. The large amount of experimental data in the literature is so diverse, that it becomes difficult and time consuming for the researcher to implement it in various areas of research. Therefore, a systematic arrangement of data and redirection in a similar fashion through web interface can assist researchers in analyzing the data as per their requirement. ExtremeDB is a freely available web based relational database which integrates general characteristics, genome-proteome information, industrial applications and recent scientific investigations of the seven major groups of 865 extremophillic microorganisms. The search options are user friendly and analyses tools such as Compare and Extreme BLAST have been incorporated for comparative analysis of two or more extremophiles and determining the sequence similarity of a given protein/nucleotide in relation to other extremophiles respectively. The effort put forth herein in the form of database, would open up new avenues on the potential utility of extremophiles in applied research. ExtremeDB is freely accessible via http://extrem.igib.res.in.
authors.affiliation: Environmental Biotechnology Division, Institute of Genomics and Integrative Biology, (IGIB-CSIR), Delhi, India.
authors.forename: Manash Chandra
authors.initials: MC
authors.lastname: Majhi
authors.forename: Abhisek Kumar
authors.initials: AK
authors.lastname: Behera
authors.forename: Niha Mohan
authors.initials: NM
authors.lastname: Kulshreshtha
authors.lastname: Mahmooduzafar
authors.forename: Rita
authors.initials: R
authors.lastname: Kumar
authors.forename: Anil
authors.initials: A
authors.lastname: Kumar
mesh_terms: D001105:Archaea / Q000235:genetics / Q000378:metabolism*; D001419:Bacteria / Q000235:genetics / Q000378:metabolism*; D016208:Databases, Factual; D020745:Genome, Archaeal / Q000235:genetics; D016680:Genome, Bacterial / Q000235:genetics; D020407:Internet; D020543:Proteome / Q000378:metabolism
chemical_list: D020543:Proteome