title: Imaging human connectomes at the macroscale.
abstract: At macroscopic scales, the human connectome comprises anatomically distinct brain areas, the structural pathways connecting them and their functional interactions. Annotation of phenotypic associations with variation in the connectome and cataloging of neurophenotypes promise to transform our understanding of the human brain. In this Review, we provide a survey of magnetic resonance imaging–based measurements of functional and structural connectivity. We highlight emerging areas of development and inquiry and emphasize the importance of integrating structural and functional perspectives on brain architecture.
authors.affiliation: Center for the Developing Brain, Child Mind Institute, New York, New York, USA.
authors.forename: R Cameron
authors.initials: RC
authors.lastname: Craddock
authors.forename: Saad
authors.initials: S
authors.lastname: Jbabdi
authors.forename: Chao-Gan
authors.initials: CG
authors.lastname: Yan
authors.forename: Joshua T
authors.initials: JT
authors.lastname: Vogelstein
authors.forename: F Xavier
authors.initials: FX
authors.lastname: Castellanos
authors.forename: Adriana
authors.initials: A
authors.lastname: Di Martino
authors.forename: Clare
authors.initials: C
authors.lastname: Kelly
authors.forename: Keith
authors.initials: K
authors.lastname: Heberlein
authors.forename: Stan
authors.initials: S
authors.lastname: Colcombe
authors.forename: Michael P
authors.initials: MP
authors.lastname: Milham
mesh_terms: D001921:Brain / Q000166:cytology / Q000502:physiology; D063132:Connectome; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010641:Phenotype