title: Safety and efficacy of tazarotene foam for the treatment of acne vulgaris.
abstract: BACKGROUND
  Tazarotene foam is the first topical retinoid foam approved for the treatment of acne vulgaris.
  
  
  OBJECTIVE
  To review the safety and efficacy studies of tazarotene foam in the treatment of moderate to severe acne.
  
  
  METHODS
  Five Phase I safety studies in normal controls are reviewed and two Phase III safety and efficacy studies in patients with moderate to severe acne are reviewed.
  
  
  CONCLUSIONS
  Tazarotene foam, 0.1% was effective in the treatment of moderate to severe acne vulgaris with an acceptable tolerability profile. This treatment provides a cosmetically favorable alternative for topical retinoid therapy.
authors.affiliation: Henry Ford Hospital, Detroit, MI, USA.
authors.forename: Erica L
authors.initials: EL
authors.lastname: Epstein
authors.forename: Linda
authors.initials: L
authors.lastname: Stein Gold
keywords: acne; foam; tazarotene; topical retinoid