title: Phosphate-tether-mediated ring-closing metathesis for the preparation of complex 1,3-anti-diol-containing subunits.
abstract: An array of examples of diastereoselective, phosphate-tether-mediated ring-closing metathesis reactions, which highlight the importance of product ring size and substrate stereochemical compatibility, as well as complexity, is reported. Studies focus primarily on the formation of bicyclo[n.3.1]phosphates, involving the coupling of C₂-symmetric dienediol subunits with a variety of simple, as well as complex, alcohol partners.
authors.affiliation: Department of Chemistry, University of Kansas, Lawrence, KS 66045, USA.
authors.forename: Rambabu
authors.initials: R
authors.lastname: Chegondi
authors.forename: Soma
authors.initials: S
authors.lastname: Maitra
authors.forename: Jana L
authors.initials: JL
authors.lastname: Markley
authors.forename: Paul R
authors.initials: PR
authors.lastname: Hanson
mesh_terms: D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis; D008958:Models, Molecular; D015394:Molecular Structure; D010710:Phosphates / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; D010710:Phosphates