title: Bleeding events associated with novel anticoagulants: a case series.
abstract: Until lately warfarin was the only valuable oral anticoagulant in stroke reduction in high risk cases with non valvular atrial fibrillation (NVAF). Although with warfarin the rate of stroke reduced notably, the major concern is the risk of serious bleeding and difficulty of establishing and maintaining the international normalised ratio (INR) within the therapeutic range. With the development of the novel anticoagulants we now have for the first time since the innovation of Warfarin feasible alternatives to it to decrease stroke rates in high risk patients with NVAF. To diminish adverse bleeding events with the novel anticoagulant proper selection of patients prior starting treatment is essential.
authors.affiliation: Barwon Health, Geelong Hospital, Victoria, Australia. Electronic address: sammirzaee@hotmail.com.
authors.forename: Sam
authors.initials: S
authors.lastname: Mirzaee
authors.forename: Tara Thi Thien
authors.initials: TT
authors.lastname: Tran
authors.forename: John
authors.initials: J
authors.lastname: Amerena
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects*; D001281:Atrial Fibrillation / Q000097:blood* / Q000188:drug therapy*; D005260:Female; D006470:Hemorrhage / Q000097:blood* / Q000139:chemically induced*; D006801:Humans; D019934:International Normalized Ratio; D008875:Middle Aged
chemical_list: D000925:Anticoagulants
keywords: Bleeding; Bleeding risk assessment; Non valvular atrial fibrilation; Novel anticoagulant; Warfarin