title: Visiting one's native country: the risks of nonadherence in HIV-infected sub-Saharan migrants--ANRS VIHVO study.
abstract: The aim of this study was to evaluate to what extent travel-related factors may cause adherence failure to antiretroviral therapy (ART) in otherwise adherent migrants when traveling back to Africa. HIV-infected sub-Saharian migrants living in France with a plasma HIV viral load < 200 copies/mL, with no change in ART for ≥3 months and who were about to visit their native country for between 2 weeks and 6 months were enrolled for the study. Patients completed a self-administered adherence questionnaire both at enrollment and during the week following their return to France. Adherence failure occurred in 23 (11.5%) of 200 patients. Negative perception about ART effectiveness (adjusted odds ratio = 4.3; 95% confidence interval = 1.3-13.7), unexpected traumatic events during their stay in their native country (7.8; 2.3-26.1), and a prolongation of their stay (5.2; 1.4-20.4) were independently associated with a higher likelihood of adherence failure. Owning/renting one's house in France (0.30; 0.10-0.96), singlehood (0.23; 0.05-1.00), and HIV status disclosure (0.19; 0.05-0.76) were correlates of sustained adherence during traveling.
authors.affiliation: AP-HP, Hôpital Avicenne, Bobigny, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Abgrall
authors.forename: Lionel
authors.initials: L
authors.lastname: Fugon
authors.forename: Nathalie
authors.initials: N
authors.lastname: Lélé
authors.forename: Estelle
authors.initials: E
authors.lastname: Carde
authors.forename: Michelle
authors.initials: M
authors.lastname: Bentata
authors.forename: Olivier
authors.initials: O
authors.lastname: Patey
authors.forename: Marie-Aude
authors.initials: MA
authors.lastname: Khuong
authors.forename: Bruno
authors.initials: B
authors.lastname: Spire
authors.forename: Patrizia
authors.initials: P
authors.lastname: Carrieri
authors.forename: Olivier
authors.initials: O
authors.lastname: Bouchaud
mesh_terms: D000328:Adult; D017954:Africa South of the Sahara / Q000208:ethnology; D015331:Cohort Studies; D005260:Female; D005602:France; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D014171:Transients and Migrants / Q000706:statistics & numerical data*; D014195:Travel / Q000706:statistics & numerical data*; D019562:Viral Load; D016903:Drug Monitoring
keywords: ART adherence; HIV/AIDS; migrants; sub-Saharan Africa; travel