title: Presentation of primary hyperparathyroidism due to adenoma.
abstract: This descriptive study was done to evaluate the clinical, biochemical and radiological findings of primary hyperthyroidism (pHPT) patients with parathyroid adenoma. This study was done in the department of Otolaryngology and Head-Neck surgery, BIRDEM, Dhaka from July 2000 to June 2007. We retrospectively reviewed the clinical presentation, biochemical and radiological features from the case records from the last 7 years of 32 patients at a tertiary care centre in Dhaka who had documented pHPT due to adenoma. Of them 18 were male and 14 were female. Mean age±SD of the patients was 42.16±11.64 years. Median preoperative serum calcium, serum phosphate and serum parathyroid hormone (PTH) levels were 11.42 mg/dL (range 8.4-14.0mg/dL), 3.11 mg/dL (range 2.5-4.5) and 293.22 pg/mL (range 65-700 pg/mL), respectively. Of all patients 75% had raised serum calcium level and 100.0% had raised serum PTH levels but all had normal serum phosphate level. Common radiological features were nephrocalcinosis, renal calculi, osteopenic changes in finger and toe, Brown tumour in forearm, 'Salt and pepper' appearance in skull, fracture of femur, fracture radius. pHPT due to adenoma in Bangladesh continues to be a symptomatic disorder with skeletal and renal manifestations.
authors.affiliation: Department of Otolaryngology-Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbagh, Dhaka, Bangladesh.
authors.forename: F A
authors.initials: FA
authors.lastname: Razib
authors.forename: M
authors.initials: M
authors.lastname: Mannan
authors.forename: A K
authors.initials: AK
authors.lastname: Biswas
authors.forename: Z
authors.initials: Z
authors.lastname: Al-Amin
authors.forename: A I
authors.initials: AI
authors.lastname: Ahsan
authors.forename: B K
authors.initials: BK
authors.lastname: Dey
authors.forename: M
authors.initials: M
authors.lastname: Wahiduzzaman
authors.forename: M A
authors.initials: MA
authors.lastname: Kamal
authors.forename: M T
authors.initials: MT
authors.lastname: Islam
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000175:diagnosis* / Q000601:surgery; D012189:Retrospective Studies