title: Interstitial lung disease in HIV.
abstract: A spectrum of noninfectious, nonmalignant lymphocytic infiltrative disorders, including nonspecific interstitial pneumonitis and lymphocytic interstitial pneumonitis, was frequently described in HIV-infected adults in the precombination antiretroviral therapy (ART) era. With the advent of ART, these conditions are less commonly encountered when caring for HIV-infected adults, possibly as a consequence of the effects of HIV treatment on pulmonary immunology. By contrast, reports of sarcoidosis among HIV-infected persons were uncommon in the pre-ART era, but sarcoidosis is increasingly recognized since the introduction of ART and may represent an immune reconstitution phenomenon. Other causes of interstitial pneumonitis are infrequently encountered among HIV-infected persons.
authors.affiliation: Department of Respiratory Medicine, Royal Sussex County Hospital, Brighton and Sussex University Hospitals NHS Trust, Eastern Road, Brighton BN2 5BE, UK. Sarah.doffman@bsuh.nhs.uk
authors.forename: Sarah R
authors.initials: SR
authors.lastname: Doffman
authors.forename: Robert F
authors.initials: RF
authors.lastname: Miller
mesh_terms: D003937:Diagnosis, Differential; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D011658:Pulmonary Fibrosis / Q000209:etiology; D011859:Radiography