title: Dentin hypersensitivity after teeth bleaching with in-office systems. Randomized clinical trial.
abstract: OBJECTIVE
  To comparatively and prospectively compare in a randomized clinical trial, dentin hypersensitivity after treatment with three in-office bleaching systems, based on hydrogen peroxide at different concentrations, with and without light source activation.
  
  
  METHODS
  88 individuals were included according to inclusion and exclusion criteria. Subjects were randomly divided into the following three treatment groups: Group 1 was treated with three 15-minute applications of hydrogen peroxide at 15% with titanium dioxide (Lase Peroxide Lite) that was light-activated (Light Plus Whitening Lase) with five cycles of 1 minute and 30 seconds each cycle, giving a total treatment time of 45 minutes; Group 2 was treated with three 10-minute applications of hydrogen peroxide at 35% (Lase Peroxide Sensy), activated by light (LPWL) same activation cycles than Group 1, with a total treatment time of 30 minutes; Group 3 was treated with only one application for 45 minutes of hydrogen peroxide at 35% (Whitegold Office) without light activation. Each subject underwent one session of bleaching on the anterior teeth according to the manufacturers' instructions. Dentin sensitivity was recorded with a visual analogue scale (VAS) at baseline, immediately after, and at 7 and 30 days after treatment using a stimulus of an evaporative blowing triple syringe for 3 seconds on the upper central incisors from a distance of 1 cm. A Kruskal-Wallis test followed by Mann-Whitney test was performed for statistical analysis.
  
  
  RESULTS
  All groups showed increased sensitivity immediately after treatment. Group 1 displayed less changes relative to baseline with no significant differences (P = 0.104). At 7 and 30 days after treatment, a comparison of VAS values indicated no significant differences between all groups (P = 0.598 and 0.489, respectively).
authors.affiliation: Department of Restorative Dentistry, School of Dentistry, University of Chile, Sergio Livingston 943, Independencia, Santiago, Chile.
authors.forename: Javier
authors.initials: J
authors.lastname: Martin
authors.forename: Eduardo
authors.initials: E
authors.lastname: Fernandez
authors.forename: Valeria
authors.initials: V
authors.lastname: Bahamondes
authors.forename: Andrea
authors.initials: A
authors.lastname: Werner
authors.forename: Klaus
authors.initials: K
authors.lastname: Elphick
authors.forename: Osmir Batista
authors.initials: OB
authors.lastname: Oliveira
authors.forename: Gustavo
authors.initials: G
authors.lastname: Moncada
mesh_terms: D000293:Adolescent; D000328:Adult; D003807:Dentin Sensitivity / Q000209:etiology*; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006861:Hydrogen Peroxide / Q000008:administration & dosage / Q000627:therapeutic use*; D054023:Lasers, Semiconductor / Q000627:therapeutic use; D008297:Male; D010147:Pain Measurement; D010778:Photochemotherapy / Q000379:methods; D017319:Photosensitizing Agents / Q000627:therapeutic use; D010789:Phototherapy / Q000379:methods; D011446:Prospective Studies; D013997:Time Factors; D014025:Titanium / Q000627:therapeutic use; D014073:Tooth Bleaching / Q000379:methods*; D058205:Tooth Bleaching Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D017319:Photosensitizing Agents; D058205:Tooth Bleaching Agents; C009495:titanium dioxide; D006861:Hydrogen Peroxide; D014025:Titanium