title: Differences in the prevalence of metabolic syndrome in boys and girls based on various definitions.
abstract: BACKGROUND
  The prevalence of metabolic syndrome (MetS) is increasing among children and adolescents. However, the prevalence of this disorder varies based on its different definitions. This study aimed to determine the prevalence of MetS in Iranian adolescents in junior high and high schools according to the definitions provided by the International Diabetes Federation (IDF) and De Ferranti.
  
  
  METHODS
  Overall, 1039 junior high school and 953 high school students were selected using multistage random sampling. Demographic data was collected using validated questionnaires. Fasting blood sugar, total cholesterol, triglyceride, high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) levels were determined. Waist circumference and blood pressure were measured by trained individuals. Subjects with MetS were selected according to two definitions provided by the IDF and De Ferranti. Chi-square and Fisher's exact tests were used to compare the prevalence of MetS and its components based on sex, school level, and the two definitions.
  
  
  RESULTS
  The mean age of junior high and high school students was 13.11 ± 1.21ad 15.93 ± 1.07 years old, respectively. The prevalence of MetS among all participants was 4.8% and 12.7% according to the definitions by the IDF and De Ferranti, respectively. It was significantly higher among boys compared to girls. According to the IDF definition, low HDL-C and hypertension were the most frequent components. Based on the De Ferranti, abdominal obesity and hypertriglyceridemia were the most frequent components.
  
  
  CONCLUSIONS
  The prevalence of MetS was higher in both groups of students based on De Ferranti definition compared to the IDF definition. The prevalence was not significantly different in boys and girls. Further studies to investigate the most suitable definition of MetS for Iranian adolescents are necessary.
authors.affiliation: Professor, Isfahan Cardiovascular Research Centre, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences.
authors.forename: Nizal
authors.initials: N
authors.lastname: Sarrafzadegan
authors.forename: Mojgan
authors.initials: M
authors.lastname: Gharipour
authors.forename: Masoumeh
authors.initials: M
authors.lastname: Sadeghi
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Nouri
authors.forename: Sedigheh
authors.initials: S
authors.lastname: Asgary
authors.forename: Sonia
authors.initials: S
authors.lastname: Zarfeshani
keywords: Adolescence; International Diabetes Federation and De Ferranti; Metabolic Syndrome