title: Effect of low level microwave radiation exposure on cognitive function and oxidative stress in rats.
abstract: Use of wireless communicating devices is increasing at an exponential rate in present time and is raising serious concerns about possible adverse effects of microwave (MW) radiation emitted from these devices on human health. The present study aimed to evaluate the effects of 900 MHz MW radiation exposure on cognitive function and oxidative stress in blood of Fischer rats. Animals were divided into two groups (6 animals/group): Group I (MW-exposed) and Group II (Sham-exposed). Animals were subjected to MW exposure (Frequency 900 MHz; specific absorption rate 8.4738 x 10(-5) W/kg) in Gigahertz transverse electromagnetic cell (GTEM) for 30 days (2 h/day, 5 days/week). Subsequently, cognitive function and oxidative stress parameters were examined for each group. Results showed significant impairment in cognitive function and increase in oxidative stress, as evidenced by the increase in levels of MDA (a marker of lipid peroxidation) and protein carbonyl (a marker of protein oxidation) and unaltered GSH content in blood. Thus, the study demonstrated that low level MW radiation had significant effect on cognitive function and was also capable of leading to oxidative stress.
authors.affiliation: Environmental Biochemistry and Molecular Biology Laboratory, Department of Biochemistry, University College of Medical Sciences & G.T.B. Hospital, University of Delhi, Dilshad Garden, Delhi 110095, India.
authors.forename: Pravin Suryakantrao
authors.initials: PS
authors.lastname: Deshmukh
authors.forename: Basu Dev
authors.initials: BD
authors.lastname: Banerjee
authors.forename: Mahesh Pandurang
authors.initials: MP
authors.lastname: Abegaonkar
authors.forename: Kanu
authors.initials: K
authors.lastname: Megha
authors.forename: Rafat Sultana
authors.initials: RS
authors.lastname: Ahmed
authors.forename: Ashok Kumar
authors.initials: AK
authors.lastname: Tripathi
authors.forename: Pramod Kumari
authors.initials: PK
authors.lastname: Mediratta
mesh_terms: D000818:Animals; D003071:Cognition / Q000528:radiation effects*; D060733:Electromagnetic Radiation; D005978:Glutathione / Q000378:metabolism; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D018782:Maze Learning; D008872:Microwaves; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000528:radiation effects*; D050050:Protein Carbonylation; D011874:Radiometry; D051381:Rats; D011916:Rats, Inbred F344; D013997:Time Factors
chemical_list: D008315:Malondialdehyde; D005978:Glutathione