title: [Study on effective constituents extracted from fibrous roots of Salvia miltiorrhiza with degrading multi-enzymes from taishan Ganoderma lucidum].
abstract: OBJECTIVE
  To study the application of degrading multi-enzymes from Ganoderma lucidum in extracting effective constituents from fibrous roots of Salvia miltiorrhiza.
  
  
  METHODS
  Effective constituents were extracted from fibrous roots by degrading multi-enzymes of wood fiber. The enzymatic parameters were optimized by the orthogonal design.
  
  
  RESULTS
  The extraction efficiencies of total tanshinones and total salvianolic acids in the extracts of fibrous roots of S. miltiorrhiza was obtained using optimum enzymolysis process reached 11.923%, 12.465%, respectively, which were 62.794%, 56.086% more than that by conventional non-enzymatic hydrolysis.
  
  
  CONCLUSIONS
  Degrading multi-enzymes of wood fiber can be used to fully extract effective constituents from fibrous roots of S. miltiorrhiza, which provides a new approach for recycling wastes of traditional Chinese medicines.
authors.affiliation: Department of Biological Sciences, Taishan Medical College, Tainan 271016, China. lingl816@163.com
authors.forename: Yan-Ling
authors.initials: YL
authors.lastname: Li
authors.forename: Xiao-Ming
authors.initials: XM
authors.lastname: Xin
authors.forename: Zeng-Min
authors.initials: ZM
authors.lastname: Miao
authors.forename: Ren-Jiu
authors.initials: RJ
authors.lastname: Shi
authors.forename: Gang-Ping
authors.initials: GP
authors.lastname: Hao
mesh_terms: D045784:Abietanes / Q000302:isolation & purification / Q000378:metabolism; D000475:Alkenes / Q000302:isolation & purification / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification* / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D018517:Plant Roots / Q000737:chemistry*; D059808:Polyphenols / Q000302:isolation & purification / Q000378:metabolism; D020940:Reishi / Q000201:enzymology*; D027561:Salvia miltiorrhiza / Q000737:chemistry*; D013696:Temperature; D014934:Wood / Q000201:enzymology
chemical_list: D045784:Abietanes; D000475:Alkenes; D004365:Drugs, Chinese Herbal; D059808:Polyphenols; C568740:salvianolic acid; C021751:tanshinone