title: Effects of chlorhexidine in self-etching adhesive: 24 hours results.
abstract: It is known that chlorhexidine (CHX) does not inhibit micro-tensile bond strengths (MTBS) when it is used in etch-and-rinse adhesives. In that technique, CHX is applied to dentin as a primer after phosphoric acid-etching before bonding with Single Bond. It would be more convenient if it is possible to incorporate CHX into the adhesive. The purpose of this study was to compare the MTBS and the FT-IR percent conversion of an all-in-one self-etching adhesives contained varying concentration of CHX. Extracted human third molars were bonded with a control all-in-one adhesive or experimental versions containing 0.5, 1, 2 or 5% CHX. The MTBS and the percent conversion of experimental adhesives containing up to 1% CHX were not significantly CHX-free control adhesives. However, addition of 2 or especially 5% CHX experimental adhesives produced significant reductions in both the MTBS and the percent conversion.
authors.affiliation: Department of Operative Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8525, Japan. nishi@md.okayama-u.ac.jp
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Nishitani
authors.forename: Keiichi
authors.initials: K
authors.lastname: Hosaka
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Hoshika
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yoshiyama
authors.forename: David H
authors.initials: DH
authors.lastname: Pashley
mesh_terms: D000704:Analysis of Variance; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D002710:Chlorhexidine / Q000494:pharmacology*; D001840:Dental Bonding / Q000379:methods*; D045662:Dental Etching / Q000379:methods; D019232:Dental Restoration Failure; D003799:Dental Stress Analysis; D003804:Dentin / Q000187:drug effects* / Q000648:ultrastructure; D017220:Dentin-Bonding Agents / Q000737:chemistry*; D006801:Humans; D008422:Materials Testing; D058105:Polymerization; D019279:Resin Cements / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D018709:Statistics, Nonparametric; D013718:Tensile Strength
chemical_list: C453842:AQ bond; D000891:Anti-Infective Agents, Local; D017220:Dentin-Bonding Agents; D019279:Resin Cements; D002710:Chlorhexidine