title: [Quality evaluation and antioxidant activity research of Schisandra chinensis from various habitats].
abstract: OBJECTIVE
  To determine the contents of lignans, crude polysaccharides (CP) and total phenolic compounds (TPC) of Schisandra chinensis from various habitats in Liaoning province and evaluate their quality and free radical scavenging (FRS) activity.
  
  
  METHODS
  Contents of schisandrol, deoxyschizandrin and schisandrin B were determined by RP-HPLC. Contents of TPC, CP and FRS activity were determined by Folin-Cicalteu's, phenol-sulfuric acid and DPPH x method, respectively.
  
  
  RESULTS
  Sample from Liaoyang city had the highest contents of lignans (21.75 mg/g); Sample from Shenbei New district of Shenyang city had the highest contents of CP (88.72 mg/g); Sample from Guanmenshan district of Benxi city had the highest contents of TPC and FRS activity (26.06 mg/g and 86.3%, respectively). Linear regression analysis results showed that contents of TPC had higher correlation coefficient with FRS activity than that of lignans. Their linear regression equations were Y = 1.3677X + 46.97, R2 = 0.6869 and Y = 2.5916X + 57.927, R2 = 0.1747 for TPC and lignans with FRS activity, respectively.
  
  
  CONCLUSIONS
  The contents of lignans, CP and TPC are significantly different from samples collected from various habitats in Liaoning province. The main antioxidative substances are TPC, and lignans have no significant correlation with FRS activity.
authors.affiliation: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China. han_zhi_fu@126.com
authors.forename: Zhi-Fu
authors.initials: ZF
authors.lastname: Han
authors.forename: Gao-Sheng
authors.initials: GS
authors.lastname: Hu
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.forename: Xing
authors.initials: X
authors.lastname: Fan
authors.forename: Jing-Ming
authors.initials: JM
authors.lastname: Jia
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry; D017705:Lignans / Q000032:analysis* / Q000737:chemistry; D010636:Phenols / Q000032:analysis* / Q000737:chemistry; D011134:Polysaccharides / Q000032:analysis* / Q000737:chemistry; D011786:Quality Control; D015203:Reproducibility of Results; D032141:Schisandra / Q000737:chemistry* / Q000254:growth & development
chemical_list: D000975:Antioxidants; D016166:Free Radical Scavengers; D017705:Lignans; D010636:Phenols; D011134:Polysaccharides