title: Management of borderline ovarian tumors.
abstract: Borderline ovarian tumors are an intermediate stage between benign cystadenomas and adenocarcinomas.
  
  
  OBJECTIVE
  The paper evaluates the management of borderline ovarian tumors (BOTs) in the patients admitted and treated in our clinic in the interval January 2003 - June 2011.
  
  
  METHODS
  The observation sheets and pathology results of 264 patients with malignant ovarian tumors were analyzed.
  
  
  RESULTS
  Of the 264 malignant ovarian tumors 74 (28.03%) were low malignant potential. Patients with BOT were aged 18-72 years (mean 46 +/- 6.2 years) and those with invasive tumors 14-83 years (mean 53 +/- 9.8 years). 92.18% were in stage 1. Sixty tumors were graded G1. 53.52 % of the tumors were over 10 cm (maximum 30 cm) in size. The histological types were: serous - 35 cases, mucinous - 19 cases, mixed (serous and mucinous) - 8 cases, and endometrioid - 2 cases. Fifteen patients presented intraepithelial carcinoma and 11 noninvasive implants into the peritoneal cavity. Five women had recurrences.
  
  
  CONCLUSIONS
  Ovarian borderline tumors with histological characteristics of carcinoma, but with good behavior are now with better defined histological features. The biggest challenge in the management of women with these tumors is to identify the subset that will behave in a malignant fashion and to develop effective treatment for them.
authors.affiliation: University of Medicine and Pharmacy, Grigore T. Popa - lasi Faculty of Medicine.
authors.forename: Mihaela-Camelia
authors.initials: MC
authors.lastname: Tîrnovanu
authors.forename: Simona
authors.initials: S
authors.lastname: Amancei
authors.forename: A
authors.initials: A
authors.lastname: Dumitrescu
authors.forename: M
authors.initials: M
authors.lastname: Onofriescu
authors.forename: Irina
authors.initials: I
authors.lastname: Dumitraşcu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002278:Carcinoma in Situ / Q000473:pathology / Q000601:surgery*; D018269:Carcinoma, Endometrioid / Q000473:pathology / Q000601:surgery*; D003537:Cystadenoma / Q000473:pathology / Q000601:surgery*; D018291:Cystadenoma, Mucinous / Q000601:surgery; D018293:Cystadenoma, Serous / Q000601:surgery; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D016347:Medical Records Systems, Computerized; D008875:Middle Aged; D060787:Neoplasm Grading; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome