title: [Constraints of the dentist are consistent with the results of an optimal irradiation with modulated intensity in N0 oropharyngeal cancer].
abstract: OBJECTIVE
  We compared intensity-modulated radiotherapy and 3D-conformal irradiation in oropharyngeal cancers according to the requirement of dentists.
  
  
  METHODS
  From the files of seven patients with cancer of the oropharynx, two dosimetry plannings for 3D-conformal radiotherapy and intensity-modulated radiotherapy with tomotherapy were performed. The dose distributions in the target volumes and organs at risk in relation to the dental sphere were compared.
  
  
  RESULTS
  For the planning target volume of the primitive tumour sites, average values of V95%, D2%, D98% and of the conformal index were statistically in favour of tomotherapy. For the planning target volume of node areas, averages values of V95%, D2%, D98% were statistically in favour of tomotherapy. For ipsi- and controlateral parotide glands, average values of V15Gy, V26Gy, V30Gy, V40Gy were significantly lower for tomotherapy. For the submaxillary glands, average values of mean doses and V40Gy were statistically in favour of tomotherapy. For the buccal cavity, the average values of V45Gy were statistically in favour of tomotherapy. For ipsi- and controlateral masseter muscles, the average values of mean doses were statistically in favour of tomotherapy. For the ipsi- and controlateral temporomandibular joints, average values of mean doses and V60Gy were statistically in favour of tomotherapy. For mandibular bone, average values of mean doses and V40Gy, V50Gy, V60Gy and V70Gy were statistically in favour of tomotherapy. For maxillary bone, average values of V40Gy, V50Gy and V60Gy were statistically in favour of tomotherapy.
  
  
  CONCLUSIONS
  The radiation oncologist can constrain the intensity-modulated radiotherapy dosimetry to the needs of dentists to prevent or improve dental care and quality of life.
authors.affiliation: Faculté Dentaire, Hôpital Civil, 67000 Strasbourg, France.
authors.forename: S
authors.initials: S
authors.lastname: Jaussaud
authors.forename: S
authors.initials: S
authors.lastname: Guihard
authors.forename: C
authors.initials: C
authors.lastname: Niederst
authors.forename: C
authors.initials: C
authors.lastname: Borel
authors.forename: P
authors.initials: P
authors.lastname: Meyer
authors.forename: P
authors.initials: P
authors.lastname: Hémar
authors.forename: P
authors.initials: P
authors.lastname: Schultz
authors.forename: G
authors.initials: G
authors.lastname: Noël
authors.forename: A
authors.initials: A
authors.lastname: Féki
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001853:Bone Marrow / Q000528:radiation effects; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D059248:Chemoradiotherapy; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003729:Dental Care; D000077143:Docetaxel; D019583:Dose Fractionation, Radiation; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D021621:Imaging, Three-Dimensional; D007568:Jaw / Q000528:radiation effects; D008198:Lymph Nodes / Q000528:radiation effects; D015182:Lymphatic Irradiation / Q000009:adverse effects / Q000379:methods; D008297:Male; D008406:Masseter Muscle / Q000528:radiation effects; D008875:Middle Aged; D009055:Mouth / Q000528:radiation effects; D009059:Mouth Diseases / Q000209:etiology / Q000517:prevention & control*; D020360:Neoadjuvant Therapy; D059351:Organ Sparing Treatments; D058958:Organs at Risk; D009959:Oropharyngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D011832:Radiation Injuries / Q000209:etiology / Q000517:prevention & control*; D011874:Radiometry; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D020266:Radiotherapy, Conformal / Q000009:adverse effects / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated / Q000009:adverse effects / Q000379:methods; D012469:Salivary Glands / Q000528:radiation effects; D043823:Taxoids / Q000008:administration & dosage; D013704:Temporomandibular Joint / Q000528:radiation effects; D014067:Tonsillar Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D014076:Tooth Diseases / Q000209:etiology / Q000517:prevention & control*
chemical_list: D043823:Taxoids; D000077143:Docetaxel; D002945:Cisplatin; D005472:Fluorouracil
keywords: Conformal irradiation; Dentist; Dentiste; Intensity-modulated radiotherapy; Irradiation conformationnelle 3D; Modulation d’intensité; Organes à risque; Organs at risk