title: [Oxidative stress in patients after kidney transplantation].
abstract: Successful kidney transplantation (KT) leads not only to normalization of renal excretory function, but also to modification of the metabolic and endocrine kidney function. The most common cause of morbidity and mortality in patients after KT are cardiovascular diseases which development is also associated with oxidative stress (OS). KT and the posttransplantation period are associated with increased OS that could gradually decrease. Some immunosuppressive drugs also contribute to increase of OS, especially compounds from a group of calcineurin inhibitors and thus indirectly contribute to increased risk of cardiovascular complications.
authors.affiliation: Ustav Lekarske chemie a biochemie Lekarske Fakulty UP Olomouc.
authors.forename: J
authors.initials: J
authors.lastname: Vostálová
authors.forename: A
authors.initials: A
authors.lastname: Galandáková
authors.forename: P
authors.initials: P
authors.lastname: Strebl
authors.forename: J
authors.initials: J
authors.lastname: Zadražil
mesh_terms: D002318:Cardiovascular Diseases / Q000209:etiology*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000502:physiology; D018384:Oxidative Stress