title: Restored kidney graft from urologist referrals for renal transplantation.
abstract: BACKGROUND
  A new transplantation program using kidneys after a small tumor excision was initiated in Western Australia in February 2007. The aim of this study was to report the outcomes over 5 years.
  
  
  METHODS
  Local urologists were encouraged to refer the kidney to the transplantation service when considering a radical nephrectomy. Recipients are selected according to strict criteria. Between February 2007 and February 2012 24 of 30 referred kidneys were restored for transplantation. Average donor age was 53.4 (range, 32-75) years while the recipients were 66.3 (range, 57-80) years. Twenty-one kidneys were restored after excision of a small tumor (<3.3 cm) and 3 kidneys were restored after being obtained from patients who had experienced complicated ureteric injuries secondary to laparotomy and colectomy.
  
  
  RESULTS
  Nineteen of 24 grafts displayed immediate function, 4 had delayed function, and 1 had nonfunction. The first 3 patients developed urinary leakages, which all resolved by subsequent management. One graft showed a pseudoaneurysm on the day 1 Doppler ultrasound, requiring interventional embolization. All patients but 1 have been off dialysis with satisfactory graft function; creatinine (Cr) levels ranged from 70 μmol/L to 330 μmol/L. There was no tumor recurrence on close follow-up from 6 to 55 months (median, 26). Three patients died due to other medical issues.
  
  
  CONCLUSIONS
  Kidneys could be restored from urologic disease for transplantation after excision of a small tumor with satisfactory outcomes at an average follow-up of 26 months. Frozen section is necessary to ensure the clearance of the tumor prior to transplantation. A modification of the surgical technique has minimized urine leakage and pseudoaneurysm formation after tumor resection.
authors.affiliation: Western Australia Liver-Kidney Transplant Service, Sir Charles Gairdner Hospital, Perth, Australia. bulang.he@health.wa.gov.au
authors.forename: B
authors.initials: B
authors.lastname: He
authors.forename: A
authors.initials: A
authors.lastname: Mitchell
authors.forename: W
authors.initials: W
authors.lastname: Lim
authors.forename: L
authors.initials: L
authors.lastname: Delriviere
mesh_terms: D000328:Adult; D000368:Aged; D003404:Creatinine / Q000097:blood; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation; D008875:Middle Aged; D012017:Referral and Consultation; D014019:Tissue Donors; D014904:Western Australia
chemical_list: D003404:Creatinine