title: [Prognosis and treatment of dry mouth. Systematic review].
abstract: There are no clearly established protocols for the treatment of dry mouth. The aim of this paper is a systematic review of the literature of the past 10 years using the words « dry mouth », « prognosis », « treatment » and « dentistry ». The initial search found 1,450 entries and within the restriction « clinical trials OR randomized controlled trial OR systemic reviews » it has been reduced to 522, which 145 were meta-analysis and systematic reviews. Papers not relevant to the issue were removed reducing the entries to 53. Twenty-four were dismissed (8 irrelevant, 7 reviews without adequate information and 9 personal opinions). Of the 29 items tested, 15 were controlled trials, 2 uncontrolled trials, 4 observational studies, 2 systematic reviews and 5 non systematic reviews. The most studied patients were Sjögren's syndrome and the irradiated patients. Treatments are focused on the etiology, prevention, symptomatic, local salivary stimulation and systemic treatments. It can be concluded that treatment must be individualized, salivary substitutes and mechanical stimulation techniques can be applied.
authors.affiliation: Departamento de Odontoestomatología, Facultad de Odontología, Universitat de Barcelona, Barcelona, España. Electronic address: 18575jll@gmail.com.
authors.forename: José
authors.initials: J
authors.lastname: López-López
authors.affiliation: Departamento de Odontoestomatología, Facultad de Odontología, Universitat de Barcelona, Barcelona, España.
authors.forename: Enric
authors.initials: E
authors.lastname: Jané Salas
authors.affiliation: Departamento de Odontoestomatología, Facultad de Odontología, Universitat de Barcelona, Barcelona, España.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Chimenos Küstner
mesh_terms: D018680:Cholinergic Antagonists / Q000009:adverse effects; D002986:Clinical Trials as Topic; D003731:Dental Caries / Q000209:etiology; D004198:Disease Susceptibility; D004311:Double-Blind Method; D005440:Fluid Therapy; D006801:Humans; D015201:Meta-Analysis as Topic; D009067:Mouthwashes / Q000627:therapeutic use; D064887:Observational Studies as Topic; D010862:Pilocarpine / Q000627:therapeutic use; D011379:Prognosis; D011812:Quinuclidines / Q000627:therapeutic use; D011832:Radiation Injuries / Q000150:complications; D011878:Radiotherapy / Q000009:adverse effects; D012464:Saliva, Artificial / Q000627:therapeutic use; D012472:Salivation / Q000187:drug effects; D012859:Sjogren's Syndrome / Q000150:complications; D013876:Thiophenes / Q000627:therapeutic use; D014987:Xerostomia / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*
chemical_list: D018680:Cholinergic Antagonists; D009067:Mouthwashes; D011812:Quinuclidines; D012464:Saliva, Artificial; D013876:Thiophenes; D010862:Pilocarpine; C059240:cevimeline
keywords: Boca seca; Dry mouth; Hiposalivación; Hyposalivation; Prognosis; Pronóstico; Tratamiento; Treatment; Xerostomia; Xerostomía