title: Factors associated with the presence of atrophic tongue in patients with dry mouth.
abstract: OBJECTIVE
  This study aimed to identify factors associated with atrophic tongue in patients with dry mouth.
  
  
  METHODS
  Discriminant analysis was performed in 1265 patients with dry mouth to identify factors that might influence the risk of developing atrophic tongue. The dependent variable was the presence of atrophic tongue, while patient age, resting saliva flow rate, stimulated saliva flow rate and Candida colony-forming units (CFU) were used as the independent variables.
  
  
  RESULTS
  The standardised linear discriminant coefficients showed that Candida CFU, stimulated saliva flow rate and age were significantly associated with the presence of atrophic tongue. The following linear discriminant function was obtained: z = 0.024 × age - 0.63 × (resting saliva flow rate) - 0.81 × (stimulated saliva flow rate) + 0.002 × Candida CFU - 0.611.
  
  
  CONCLUSIONS
  High Candida CFU, low stimulated saliva flow rate and advanced age were identified as closely associated factors for the risk of development of atrophic tongue.
authors.affiliation: Department of Clinical Pathophysiology, Tsurumi University Dental Hospital, Yokohama, Japan; Department of Geriatric Dentistry, Tsurumi University School of Dental Medicine, Yokohama, Japan.
authors.forename: Hisato
authors.initials: H
authors.lastname: Kimori
authors.forename: Ken
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Shigeo
authors.initials: S
authors.lastname: Yamachika
authors.forename: Akihisa
authors.initials: A
authors.lastname: Tsurumoto
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kamikawa
authors.forename: Mami
authors.initials: M
authors.lastname: Sasao
authors.forename: Mitsuhiko
authors.initials: M
authors.lastname: Morito
authors.forename: Ichiro
authors.initials: I
authors.lastname: Saito
authors.forename: Tomoko
authors.initials: T
authors.lastname: Ohshima
authors.forename: Nobuko
authors.initials: N
authors.lastname: Maeda
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Nakagawa
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001284:Atrophy / Q000209:etiology* / Q000382:microbiology; D002175:Candida / Q000254:growth & development; D015169:Colony Count, Microbial; D003430:Cross-Sectional Studies; D005260:Female; D005928:Glossitis / Q000209:etiology* / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000378:metabolism*; D012636:Secretory Rate; D014059:Tongue / Q000382:microbiology / Q000503:physiopathology*; D014987:Xerostomia / Q000150:complications* / Q000382:microbiology; D055815:Young Adult
keywords: Candida; atrophic tongue; dry mouth