title: [Initial experience of percutaneous coronary intervention guided by computed tomography coronary angiography derived roadmap and magnetic navigation system].
abstract: OBJECTIVE
  To evaluate the feasibility, efficacy and safety of the percutaneous coronary intervention (PCI)guided by computed tomography (CT) coronary angiography derived roadmap and magnetic navigation system (MNS).
  
  
  METHODS
  During June 2011 and May 2012, thirty consecutive patients receiving elective PCI were enrolled, coronary artery disease was primarily diagnosed by dual-source CT coronary angiography (DSCT-CA) at outpatient clinic and successively proved by coronary artery angiography in the hospital. Target vessels from pre-procedure DSCT-CA were transferred to the magnetic navigation system, and consequently edited, reconstructed, and projected onto the live fluoroscopic screen as roadmap. Parameters including characters of the target lesions, time, contrast volume, radiation dosage for guidewire crossing, and complications of the procedure were recorded.
  
  
  RESULTS
  Thirty patients with 36 lesions were recruited and intervened by PCI. Among the target lesions, sixteen were classified as type A, 11 as type B1, 8 as type B2, 1 as type C. The average length of the target lesions was (22.0 ± 9.8) mm, and the average stenosis of the target lesions was (81.3 ± 10.3)%. Under the guidance of CT roadmap and MNS, 36 target lesions were crossed by the magnetic guidewires, with a lesion crossing ratio of 100%. The time of placement of the magnetic guidewires was 92.5 (56.6 - 131.3) seconds. The contrast volume and the radiation dosage for guidewire placement were 0.0 (0.0 - 3.0) ml and 235.0 (123.5 - 395.1) µGym(2)/36.5 (21.3 - 67.8) mGy, respectively. Guidewires were successfully placed in 21 (58.3%) lesions without contrast agent. All enrolled vessels were successfully treated, and there were no MNS associated complications.
  
  
  CONCLUSIONS
  It is feasible, effective and safe to initiate PCI under the guidance of CT derived roadmap and MNS. This method might be helpful for the guidewire placement in the treatment of total occlusions.
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
authors.forename: Qiu
authors.initials: Q
authors.lastname: Zhang
authors.forename: De-yu
authors.initials: DY
authors.lastname: Kong
authors.forename: Chun-jian
authors.initials: CJ
authors.lastname: Li
authors.forename: Bo
authors.initials: B
authors.lastname: Chen
authors.forename: En-zhi
authors.initials: EZ
authors.lastname: Jia
authors.forename: Lei-Lei
authors.initials: LL
authors.lastname: Chen
authors.forename: Qing-zhe
authors.initials: QZ
authors.lastname: Jia
authors.forename: Zhen-hua
authors.initials: ZH
authors.lastname: Dai
authors.forename: Tian-tian
authors.initials: TT
authors.lastname: Zhu
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.forename: Jie
authors.initials: J
authors.lastname: Liu
authors.forename: Tie-bing
authors.initials: TB
authors.lastname: Zhu
authors.forename: Zhi-jian
authors.initials: ZJ
authors.lastname: Yang
authors.forename: Ke-jiang
authors.initials: KJ
authors.lastname: Cao
mesh_terms: D000368:Aged; D017023:Coronary Angiography / Q000379:methods*; D005260:Female; D006801:Humans; D008280:Magnetics; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention; D014057:Tomography, X-Ray Computed