title: Clinical efficacy of the 595 nm pulsed dye laser in the treatment of childhood superficial hemangioma - analysis of 10-year application in Chinese patients.
abstract: Abstract Background: The 595 nm tunable pulsed dye laser has been used in China for more than 10 years. However, no studies about its effect and side-effect in treatment of superficial hemangioma have been documented.
  
  
  OBJECTIVE
  This study was designed to retrospectively summarize its usage in Chinese patients.
  
  
  METHODS
  Infant patients with superficial hemangioma, who had received 595 nm tunable pulsed dye laser treatment in our laser center in the last 10 years, were recruited. Detailed demographics, results of assessment about their degree of clearance and clinical examination for treatment complications were entered into SASS10.0 version database, and statistical analyses were conducted.
  
  
  RESULTS
  Six hundred and fifty-seven cases with superficial hemangioma were recruited. The overall effectiveness rate was 91.17%. Female patients respond better than male, the difference was statistically significant (p<0.001). Lesions at different part of the body respond differently to the treatment with lesions on extremities show the best result. The response rate does not increase with time of treatments. The most common side-effects were pigment changes and skin atrophy, which usually resolve spontaneously and disappear completely in a few months.
  
  
  CONCLUSIONS
  Our experience confirmed the satisfactory clinical efficacy and safety of the 595 nm tunable pulse dye laser in the treatment of childhood superficial hemangioma.
authors.affiliation: Institute of Dermatology & Department of Dermatology, No.1 Hospital, Anhui Medical University , Hefei, Anhui, 230032, PR , China and.
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
authors.forename: Shengxiu
authors.initials: S
authors.lastname: Liu
authors.forename: Chunjun
authors.initials: C
authors.lastname: Yang
authors.forename: Sen
authors.initials: S
authors.lastname: Yang
mesh_terms: D044466:Asian People; D002681:China; D005260:Female; D006391:Hemangioma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D054025:Lasers, Dye / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D012189:Retrospective Studies; D012871:Skin Diseases / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome
keywords: Hemangioma; pulsed dye laser; side-effect