title: Five new indole alkaloids from the leaves of Rauvolfia yunnanensis.
abstract: Five new indole alkaloids, rauvoloids A-E (1-5), together with two known ones, raucaffrinoline (6) and perakine (7) were isolated from the leaves of Rauvolfia yunnanensis. Their structures were elucidated by extensive spectroscopic methods. Structurally, rauvoloids A (1), B-C (2-3) and D (4) with unusual substitution patterns (no substitution, Cl and (1E)-3-oxo-butenyl, respectively) at C-20, are the first examples of perakine-type alkaloids with C18 and C22 skeletons.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China.
authors.forename: Chang-An
authors.initials: CA
authors.lastname: Geng
authors.forename: Xi-Kui
authors.initials: XK
authors.lastname: Liu
mesh_terms: D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D011926:Rauwolfia / Q000737:chemistry*
chemical_list: D026121:Indole Alkaloids; D010936:Plant Extracts
keywords: Indole alkaloids; Rauvolfia yunnanensis; Rauvoloids A–E