title: Treatment of quetiapine overdose with intravenous lipid emulsion.
abstract: We report the case of a 29-year-old woman who attempted suicide by oral ingestion of potentially fatal doses of multiple drugs including quetiapine. Intravenous lipid emulsion (ILE) was administered at a dose higher than that used in the standard management of toxicity. Rapid improvement was observed in the patient's status, and no additional treatment was required during the period of observation. No adverse effect of lipid administration was observed. ILE treatment seems to have great potential in the management of lipophilic drug toxicity in the future.
authors.affiliation: Emergency Department, Ankara Numune Training and Research Hospital, Samanpazarı, Ankara, Turkey. mdengindeniz@yahoo.com
authors.forename: Engin Deniz
authors.initials: ED
authors.lastname: Arslan
authors.forename: Ali
authors.initials: A
authors.lastname: Demir
authors.forename: Fevzi
authors.initials: F
authors.lastname: Yilmaz
authors.forename: Cemil
authors.initials: C
authors.lastname: Kavalci
authors.forename: Evvah
authors.initials: E
authors.lastname: Karakilic
authors.forename: Elif
authors.initials: E
authors.lastname: Çelikel
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000633:toxicity*; D003987:Dibenzothiazepines / Q000633:toxicity*; D062787:Drug Overdose / Q000628:therapy*; D005217:Fat Emulsions, Intravenous / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D000069348:Quetiapine Fumarate; D013406:Suicide, Attempted; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D005217:Fat Emulsions, Intravenous; D000069348:Quetiapine Fumarate