title: Fluid management in cardiac surgery: colloid or crystalloid?
abstract: The crystalloid-colloid debate has raged for decades, with the publication of many meta-analyses, yet no consensus. There are important differences between colloids and crystalloids, and these differences have direct relevance for cardiac surgical patients. Rather than asking crystalloid or colloid, we believe better questions to ask are (1) High or low chloride content? and (2) Synthetic or natural colloid? In this paper we review the published literature regarding fluid therapy in cardiac surgery and explain the background to these two important and unanswered questions.
authors.affiliation: Department of Anesthesiology, Duke University Medical Center/Durham VAMC, Erwin Road, Durham, NC 27710, USA. Andrew.Shaw@duke.edu
authors.forename: Andrew
authors.initials: A
authors.lastname: Shaw
authors.forename: Karthik
authors.initials: K
authors.lastname: Raghunathan
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D001281:Atrial Fibrillation / Q000517:prevention & control; D006348:Cardiac Surgical Procedures / Q000379:methods*; D002314:Cardioplegic Solutions; D003102:Colloids / Q000627:therapeutic use*; D000077324:Crystalloid Solutions; D005440:Fluid Therapy / Q000379:methods*; D006801:Humans; D007552:Isotonic Solutions / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control; D012462:Saline Solution, Hypertonic / Q000627:therapeutic use
chemical_list: D002314:Cardioplegic Solutions; D003102:Colloids; D000077324:Crystalloid Solutions; D007552:Isotonic Solutions; D012462:Saline Solution, Hypertonic