title: [Expression and clinical significance of serum interleukin-27 level in patients with oral squamous cell carcinoma].
abstract: OBJECTIVE
  To explore the clinical significance of serum interleukin-27 (IL-27) level in patients with oral squamous cell carcinoma (OSCC).
  
  
  METHODS
  Forty patients pathologically confirmed as OSCC were included, and 20 healthy adults were used as controls. The serum IL-27 were tested with enzyme -linked immunosorbent assay(ELISA). Statistical analysis was performed by SPSS10.0 software package and t test was used to determine the difference.
  
  
  RESULTS
  The level of serum IL-27 in OSCC patients was significantly higher than that in the control group(P<0.05). The high expression of IL-27 correlated with clinical pathologic stage (P<0.05) and cervical lymph node metastasis (P<0.05).
  
  
  CONCLUSIONS
  The expression of serum IL-27 correlates significantly with the clinicopathologic stages of OSCC.
authors.affiliation: Department of Clinical Laboratory, Baoshan Traditional Chinese and Western Medicine Hospital, Shanghai, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Liu
authors.forename: Zu-jun
authors.initials: ZJ
authors.lastname: Sun
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007378:Interleukins / Q000097:blood*; D008207:Lymphatic Metastasis; D009062:Mouth Neoplasms
chemical_list: D007378:Interleukins; C464565:MYDGF protein, human