title: Recommendations for the diagnosis of human papilloma virus (HPV) high and low risk in the prevention and treatment of diseases of the oral cavity, pharynx and larynx. Guide of experts PTORL and KIDL.
abstract: The role of human papilloma viruses (HPV) in malignant and nonmalignant ENT diseases and the corresponding epidemiological burden has been widely described. International head and neck oncology community discussed growing evidence that oral HPV infection contributes to the risk of oro-pharyngeal carcinoma (OPC) and recommended HPV testing as a part of the work up for patients with OPC. Polish Society of ENT Head Neck Surgery and National Chamber of Laboratory Diagnosticians have worked together to define the minimum requirements for assigning a diagnosis of HPV-related conditions and testing strategy that include HPV specific tests in our country. This paper briefly frames the literature information concerning low risk (LR) and high risk (HR) HPV, reviews the epidemiology, general guidance on the most appropriate biomarkers for clinical assessment of HPV. The definition of HPV-related cancer was presented. The article is aiming to highlight some of major issues for the clinician dealing with patients with HPV-related morbidities and to introduce the diagnostic algorithm in Poland.
authors.affiliation: Klinika Otolaryngologii i Onkologii Laryngologicznej UM w Poznaniu, ul. Przybyszewskiego 49, 60-355 Poznań, Poland. gowierzb@yahoo.co.uk
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Wierzbicka
authors.forename: Agata
authors.initials: A
authors.lastname: Józefiak
authors.forename: Jarosław
authors.initials: J
authors.lastname: Szydłowski
authors.forename: Andrzej
authors.initials: A
authors.lastname: Marszałek
authors.forename: Czesław
authors.initials: C
authors.lastname: Stankiewicz
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Hassman-Poznańska
authors.forename: Ewa
authors.initials: E
authors.lastname: Osuch-Wójcikiewicz
authors.forename: Jacek
authors.initials: J
authors.lastname: Składzień
authors.forename: Janusz
authors.initials: J
authors.lastname: Klatka
authors.forename: Wioletta
authors.initials: W
authors.lastname: Pietruszewska
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Puacz
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Szyfter
authors.forename: Witold
authors.initials: W
authors.lastname: Szyfter
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D007830:Larynx / Q000821:virology; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000821:virology; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000628:therapy* / Q000821:virology; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000453:epidemiology / Q000821:virology; D010610:Pharyngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D010614:Pharynx / Q000821:virology; D011044:Poland / Q000453:epidemiology; D017410:Practice Guidelines as Topic; D015995:Prevalence