title: Why aortic elasticity differs among classical and non-classical mitral valve prolapsed?
abstract: BACKGROUND
  Mitral valve prolapse (MVP) is the most common valvular heart disease and characterized by the displacement of an abnormally thickened mitral valve leaflet into the left atrium during systole. There are two types of MVP, broadly classified as classic (thickness ≥5 mm) and non-classic (thickness <5 mm) according to the morphology of the leaflets. We aimed to investigate elastic properties of the aorta in young male patients with classical and non-classical MVP.
  
  
  METHODS
  In the present study, 63 young adult males (mean age: 22.7 ± 4.2) were included. Patients were divided into classic MVP (n = 27) and non-classic MVP (n = 36) groups. Aortic strain, aortic distensibility and aortic stiffness index were calculated by using aortic diameters obtained by echocardiography and blood pressures measured by sphygmomanometer.
  
  
  RESULTS
  There was no significant difference between the groups in terms of age, body mass index, left ventricular mass and ejection fraction. When comparing the MVP group it was found that aortic strain and aortic distensibility were increased (p = 0.0027, p = 0.016, respectively) whereas the aortic stiffness index was decreased (p = 0.06) in the classical MVP group.
  
  
  CONCLUSIONS
  We concluded that the elastic properties of the aorta is increased in patients with classic MVP. Further large scale studies should be performed to understand of morphological and physiological properties of the aorta in patients with MVP.
authors.affiliation: Department of Cardiology, Beytepe Hospital , Ankara , Turkey .
authors.forename: Murat
authors.initials: M
authors.lastname: Unlu
authors.forename: Sait
authors.initials: S
authors.lastname: Demirkol
authors.forename: Mustafa
authors.initials: M
authors.lastname: Aparci
authors.forename: Zekeriya
authors.initials: Z
authors.lastname: Arslan
authors.forename: Sevket
authors.initials: S
authors.lastname: Balta
authors.forename: Umuttan
authors.initials: U
authors.lastname: Dogan
authors.forename: Baris
authors.initials: B
authors.lastname: Kilicarslan
authors.forename: Ozcan
authors.initials: O
authors.lastname: Ozeke
authors.forename: Turgay
authors.initials: T
authors.lastname: Celik
authors.forename: Atila
authors.initials: A
authors.lastname: Iyisoy
mesh_terms: D000293:Adolescent; D000328:Adult; D001011:Aorta / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology; D004452:Echocardiography / Q000379:methods; D004548:Elasticity / Q000502:physiology*; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000502:physiology*; D008945:Mitral Valve Prolapse / Q000175:diagnosis / Q000503:physiopathology*; D059289:Vascular Stiffness / Q000502:physiology*; D055815:Young Adult