title: Next generation therapeutics for Alzheimer's disease.
abstract: To date, no truly effective therapy has been developed for Alzheimer's disease or mild cognitive impairment. In searching for new approaches that may succeed where previous ones have failed, it may be instructive to consider the successful therapeutic developments for other chronic illnesses such as cancer and human immunodeficiency virus.
authors.affiliation: Buck Institute for Research on Aging, Novato, CA, USA. dbredesen@buckinstitute.org
authors.forename: Dale E
authors.initials: DE
authors.lastname: Bredesen
authors.forename: Varghese
authors.initials: V
authors.lastname: John
mesh_terms: D000375:Aging; D000544:Alzheimer Disease / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D016229:Amyloid beta-Peptides / Q000037:antagonists & inhibitors / Q000378:metabolism; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D000818:Animals; D053327:Apolipoprotein E4 / Q000235:genetics / Q000378:metabolism; D006801:Humans; D051379:Mice; D014807:Vitamin D / Q000378:metabolism
chemical_list: D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor; D053327:Apolipoprotein E4; D014807:Vitamin D