title: Perceptions and acceptability of HPV vaccination among parents of young adolescents: a multicenter national survey in China.
abstract: Prophylactic HPV vaccines target young adolescents to prevent related cervical lesions and even genital warts prior to onset of sexual activity. Parental consent is often essential for success of vaccination program for this age group. We conducted a national multicenter study to explore the acceptability of HPV vaccination among parents of young adolescents and associated factors in relevant parent decision making in China. A total of 2899 parents of young adolescents (11-17 years) participated in the survey between November 28, 2011 and May 9, 2012, but four were excluded from analysis because of inconsistencies in their given information in the questionnaire. Mothers accounted for 62.8% of the parent participants. The mean age of the parents was 40.40 (standard deviation, 4.68) years. Only 36.2% of the parents accepted the vaccine for their children. Knowledge about HPV and HPV vaccine was a positive correlate with HPV vaccination acceptability (Ptrend=0.003). Grade of child (Ptrend=0.015), prior vaccination experience outside the National Expanded Program on Immunization (OR: 1.43; 95%CI: 1.19-1.72), fear of cervical cancer and/or genital warts (OR: 2.47; 95%CI: 2.00-3.05), and prior consultation regarding HPV vaccine information (OR: 2.35; 95%CI: 1.57-3.52) were also positively associated with higher HPV vaccine acceptability. The acceptability was lower in mothers (OR: 0.45; 95%CI: 0.37-0.54) and who had better education (Ptrend=0.009). 57.3% of the parents agreed that the most appropriate venue for HPV vaccination was the local center for disease prevention and control. In conclusion, our study indicates a low acceptability of HPV vaccination among parents of young adolescents in China. We understand there are many challenges in implementing HPV vaccination program. Our findings will serve as valuable references for future HPV vaccination policies and campaigns after HPV vaccines are approved in China.
authors.affiliation: Department of Cancer Epidemiology, Cancer Institute of Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
authors.forename: Shao-Kai
authors.initials: SK
authors.lastname: Zhang
authors.forename: Xiong-Fei
authors.initials: XF
authors.lastname: Pan
authors.forename: Shao-Ming
authors.initials: SM
authors.lastname: Wang
authors.forename: Chun-Xia
authors.initials: CX
authors.lastname: Yang
authors.forename: Xiao-Hong
authors.initials: XH
authors.lastname: Gao
authors.forename: Zeng-Zhen
authors.initials: ZZ
authors.lastname: Wang
authors.forename: Man
authors.initials: M
authors.lastname: Li
authors.forename: Ze-Fang
authors.initials: ZF
authors.lastname: Ren
authors.forename: Fang-Hui
authors.initials: FH
authors.lastname: Zhao
authors.forename: You-Lin
authors.initials: YL
authors.lastname: Qiao
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002681:China; D003218:Condylomata Acuminata / Q000517:prevention & control / Q000821:virology; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D030361:Papillomavirus Infections / Q000517:prevention & control; D053918:Papillomavirus Vaccines / Q000627:therapeutic use*; D010290:Parents / Q000523:psychology*; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data*; D002583:Uterine Cervical Neoplasms / Q000517:prevention & control / Q000821:virology; D014611:Vaccination / Q000523:psychology*
chemical_list: D053918:Papillomavirus Vaccines