title: Case of neuro-Behçet's disease successfully maintained a remission using infliximab for 2 years.
abstract: Behçet's disease is a systemic inflammatory disorder with chronic remissions and relapses. Involvement of the central nervous system, called neuro-Behçet's disease (NBD), is a serious complication. Although corticosteroids and immunosuppressive agents are used, there is no definite standard of treatment with long term-effects for NBD. Here, we report a female case with NBD successfully treated by infliximab and corticosteroids for 2 years. Our report suggests treatment with infliximab may be effective for long-term remission of NBD.
authors.affiliation: Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
authors.forename: Hisashi
authors.initials: H
authors.lastname: Kanemaru
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Makino
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Jinnin
authors.forename: Aya
authors.initials: A
authors.lastname: Yonemitsu
authors.forename: Katsunari
authors.initials: K
authors.lastname: Makino
authors.forename: Hironobu
authors.initials: H
authors.lastname: Ihn
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D001528:Behcet Syndrome / Q000188:drug therapy*; D002493:Central Nervous System Diseases / Q000188:drug therapy*; D005260:Female; D006801:Humans; D000069285:Infliximab; D012074:Remission Induction / Q000379:methods
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000911:Antibodies, Monoclonal; D000069285:Infliximab
keywords: Behçet's disease; infliximab; long-term effects; neuro-Behçet's disease; tumor necrosis factor-α