title: Comment on: EGFR mutational status in Brazilian patients with penile carcinoma.
abstract: The authors describe the results on EGFR molecular alterations of 29 Brazilian patients with penile carcinoma (PC). DNA extracted from frozen tumor tissue of all patients was submitted to direct sequencing of the four exons (18 - 21) responsible for the EGFR tyrosine-kinase activity. Corroborating the data by Di Lorenzo et al. published in Expert Opin Ther Targets, none of the sequenced tumor samples showed relevant alterations in the four studied exons of the EGFR gene.
authors.forename: Alice Muglia Thomaz da
authors.initials: AM
authors.lastname: Silva
authors.forename: Bianca Cristina Garcia
authors.initials: BC
authors.lastname: Lisboa
authors.forename: Isabela Werneck da
authors.initials: IW
authors.lastname: Cunha
authors.forename: Rafael Malagoli
authors.initials: RM
authors.lastname: Rocha
authors.forename: Stenio Cassio
authors.initials: SC
authors.lastname: Zequi
authors.forename: Gustavo Cardoso
authors.initials: GC
authors.lastname: Guimarães
authors.forename: José
authors.initials: J
authors.lastname: Vassallo
authors.forename: Fernando Augusto
authors.initials: FA
authors.lastname: Soares
mesh_terms: D066246:ErbB Receptors / Q000235:genetics*; D006801:Humans; D008297:Male; D010412:Penile Neoplasms / Q000235:genetics*
chemical_list: D066246:ErbB Receptors