title: TiPs: a database of therapeutic targets in pathogens and associated tools.
abstract: BACKGROUND
  The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes.
  
  
  METHODS
  The TiPs database is freely available at http://biocomputing.it/tips.
  
  
  BACKGROUND
  anna.tramontano@uniroma1.it or allegra.via@uniroma1.it.
authors.affiliation: Department of Physics, Sapienza University, 00185 Rome, Italy.
authors.forename: Rosalba
authors.initials: R
authors.lastname: Lepore
authors.forename: Anna
authors.initials: A
authors.lastname: Tramontano
authors.forename: Allegra
authors.initials: A
authors.lastname: Via
mesh_terms: D001665:Binding Sites; D062313:Databases, Pharmaceutical; D055808:Drug Discovery; D006801:Humans; D007239:Infections / Q000188:drug therapy; D008958:Models, Molecular; D004364:Pharmaceutical Preparations / Q000737:chemistry; D011506:Proteins / Q000737:chemistry / Q000187:drug effects; D012984:Software
chemical_list: D004364:Pharmaceutical Preparations; D011506:Proteins