title: [Discectomy and discectomy plus Coflex fixation for lumbar disc herniation, a clinical comparison study].
abstract: OBJECTIVE
  To compare clinical efficacy between discectomy and discectomy plus Coflex fixation for lumbar disc herniation.
  
  
  METHODS
  From December 2007 to August 2008, 50 patients (31 males and 19 females) were treated by surgery of discectomy and discectomy plus Coflex fixation. The average age was 52.5 years (range, 30 - 72 years). There were 24 cases in the group of discectomy plus Coflex fixation and 26 cases in the group of discectomy. Preoperative and postoperative visual analogue scales (VAS), Japanese Orthopadic Association (JOA) and Oswestry disability index (ODI) were recorded, as well as radiological index. And use a paired t-test and one-way analysis of variance (one-way ANOVA) statistical method to evaluate the Coflex dynamic stabilization system in value in the treatment of lumbar disc herniation.
  
  
  RESULTS
  Both groups received significant improvement of JOA, ODI and VAS (t = -33.2 - 64.5, P < 0.01), but the group of discectomy was found with deterioration of ODI at last follow-up, 12 months after surgery 6.7 ± 1.5 to 10.2 ± 2.3 (t = -19.3, P < 0.05). The group of discectomy plus Coflex fixation was found with significant increase of height of dorsal intervertebral discs (HD), distance across the two adjacent spinous processes (DS), distance of intervertebral foramina (DIF) and spinal canal area(SA) (t = -34.4 - 4.5, P < 0.05). In contrast, the group of discectomy was found with significant decrease of HD, DS, DIF and SA (t = 3.4 - 52.8, P < 0.05). Coflex fixed group in HD, DIF, DS significant difference with simple discectomy group, with a statistically significant (F = 14.1 - 25.6, P < 0.05).
  
  
  CONCLUSIONS
  Both discectomy and discectomy plus Coflex fixation are apparently effective when treating lumbar disc herniation. Coflex can significantly increase the HD and DIF when used for lumbar disc herniation, and it has positive influence for keeping height of lumbar vertebral space and treating the nerve root symptom of lumbar disc herniation. Discectomy plus Coflex is better than pure discectomy in preventing lumbar degeneration.
authors.affiliation: Department of Spine Surgery, the Second Affiliated Hospital of Wenzhou Medical College, Wenzhou 325000, China.
authors.forename: Ding
authors.initials: D
authors.lastname: Xu
authors.forename: Hua-zi
authors.initials: HZ
authors.lastname: Xu
authors.forename: Yi-heng
authors.initials: YH
authors.lastname: Chen
authors.forename: Yong-long
authors.initials: YL
authors.lastname: Chi
authors.forename: Wen-fei
authors.initials: WF
authors.lastname: Ni
authors.forename: Qi-shan
authors.initials: QS
authors.lastname: Huang
authors.forename: Xiang-yang
authors.initials: XY
authors.lastname: Wang
authors.forename: Yan
authors.initials: Y
authors.lastname: Lin
authors.forename: Fang-min
authors.initials: FM
authors.lastname: Mao
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D016268:Internal Fixators; D007405:Intervertebral Disc Displacement / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome