title: Thrombosis and cancer: emerging data for the practicing oncologist.
abstract: The American Society of Clinical Oncology (ASCO) recently updated clinical practice guidelines on the treatment and prevention of venous thromboembolism (VTE) in patients with cancer. Although several new studies have been reported, many questions remain about the close relationship between VTE and malignant disease. The risk of VTE among patients with cancer continues to increase and is clearly linked to patient-, disease- and treatment-specific factors. In general, VTE among patients with cancer is treated in a similar fashion to that in other patient populations. However, the greater risk of VTE in patients with cancer, the multitude of risk factors, and the greater risk of VTE recurrence and mortality among patients with cancer pose important challenges for surgeons, oncologists, and other providers.
authors.affiliation: From the Duke University and the Duke Cancer Institute, Durham, NC; Department of Solid Tumor Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH; Immunohematology Division, Hospital Papa Giovanni XXIII, Bergamo, Italy.
authors.forename: Gary H
authors.initials: GH
authors.lastname: Lyman
authors.forename: Alok A
authors.initials: AA
authors.lastname: Khorana
authors.forename: Anna
authors.initials: A
authors.lastname: Falanga
mesh_terms: D000818:Animals; D001777:Blood Coagulation; D001779:Blood Coagulation Factors / Q000378:metabolism; D018450:Disease Progression; D006801:Humans; D008495:Medical Oncology / Q000592:standards; D009369:Neoplasms / Q000097:blood / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors; D015398:Signal Transduction; D054556:Venous Thromboembolism / Q000097:blood / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*
chemical_list: D001779:Blood Coagulation Factors