title: The egg and the nucleus: a battle for supremacy.
abstract: Sir John Gurdon and Professor Shinya Yamanaka were the recipients of the 2012 Nobel Prize for Physiology or Medicine. This Spotlight article is a commentary on the early nuclear transplant work in Xenopus, which was very important for the Nobel award in 2012, and the influence of this work on the reprogramming field.
authors.affiliation: Wellcome Trust/Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK. j.gurdon@gurdon.cam.ac.uk
authors.forename: J B
authors.initials: JB
authors.lastname: Gurdon
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D002467:Cell Nucleus / Q000235:genetics* / Q000378:metabolism; D065150:Cellular Reprogramming; D019976:Cloning, Organism / Q000266:history / Q000379:methods*; D004625:Embryo, Nonmammalian / Q000166:cytology / Q000196:embryology / Q000378:metabolism; D047108:Embryonic Development; D004707:Endoderm / Q000166:cytology / Q000378:metabolism; D044127:Epigenesis, Genetic; D049673:History, 20th Century; D049674:History, 21st Century; D051379:Mice; D009613:Nobel Prize; D053652:Nuclear Transfer Techniques / Q000266:history; D010063:Ovum / Q000166:cytology* / Q000378:metabolism; D010827:Physiology / Q000266:history; D014981:Xenopus / Q000196:embryology / Q000235:genetics