title: Medicinal plants and their uses by the people in the Region of Randa, Djibouti.
abstract: BACKGROUND
  The article presents the local knowledge on medicinal plants and their relevance in managing health problems. Important ethnobotanical leads are given with priority species and disease categories, casting insight on future phytochemical and pharmacological studies.
  
  
  OBJECTIVE
  The use of traditional medicinal plants has been an integral part of the traditional healthcare systems in Djibouti. However, scientific studies on the traditional herbal healing systems of the various cultural groups have never been undertaken. This study has, therefore, aimed at assessing plant-related ethnomedicinal knowledge of the people in Randa Region; prioritising the plants with respect to common disease categories and inferring about prospects of new pharmacological products.
  
  
  METHODS
  Interview-based ethnobotanical field study was carried out to document the plant-based ethnomedicinal knowledge handed down to the present by the oral tradition of people living in 24 villages in Tadjourah District of Randa Region (north Djibouti). Informant Consensus Factors (ICF) and Fidelity Level (FL) values of the medicinal plants were calculated to check the level of informant agreement and the healing potentials of the species.
  
  
  RESULTS
  A total of 91 plant species that belong to 72 genera and 40 families were documented. Most of these species (92%) were collected from non-cultivated areas. Their local names and traditional uses in medicine were also studied. The plant family Fabaceae was represented by the highest number of taxa (17 species). Strong informant agreements hinted at good healing potentials of some species as shown by high values of consensus factors for eye diseases (0.98), mouth diseases (0.93), kidney problems (0.89) and microbial infections (0.84). Dodonea angustifolia, Solanum cordatum, Grewia erythraea, Acalypha indica, Acacia etbaica, Fagonia schweinfurthii, Solanum coagulans, Senna alexandrina and Grewia tembensis scored high FL values emerging as promising priority species for future pharmacological screening against microbial infections.
  
  
  CONCLUSIONS
  The results of this study may inspire further ethnobotanical and ethnopharmacological research and investigations toward drug discovery in Djibouti and beyond.
authors.affiliation: Institut de Recherches Medicinales CERD, Djibouti. Shaimaa24@gmail.com
authors.forename: Alshaimaa
authors.initials: A
authors.lastname: Hassan-Abdallah
authors.forename: Ali
authors.initials: A
authors.lastname: Merito
authors.forename: Souad
authors.initials: S
authors.lastname: Hassan
authors.forename: Djaltou
authors.initials: D
authors.lastname: Aboubaker
authors.forename: Mahdi
authors.initials: M
authors.lastname: Djama
authors.forename: Zemede
authors.initials: Z
authors.lastname: Asfaw
authors.forename: Ensermu
authors.initials: E
authors.lastname: Kelbessa
mesh_terms: D003625:Data Collection / Q000379:methods; D015730:Djibouti; D019448:Ethnobotany / Q000379:methods*; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008519:Medicine, Traditional / Q000379:methods*; D008517:Phytotherapy / Q000379:methods*; D028321:Plant Preparations / Q000737:chemistry / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D028321:Plant Preparations