title: Clinical and pathological characteristics of intraocular cysticercosis.
abstract: This study aimed to explore the clinical, radiological, and pathological characteristics of intraocular cysticercosis due to Taenia solium metacestode infection. Total 8 patients diagnosed with intraocular cysticercosis at the Red Cross Hospital of Yunnan Province, China were examined retrospectively. Patients with clear dioptic media had undergone fundus chromophotography. All patients underwent B ultrasonography of the ocular region (CT) successive scanning of the orbit and cerebral tissues. Parasites were extracted surgically and then examined pathologically. The fundus chromophotography showed a white and condensing scolex package in the vesicle. The B ultrasonic examination showed a vesicle-like echogenic mass in the vitreous chamber, in which the high-level echo spot was the cysticercus scolex. The pathological examinations showed that the vesicle wall exhibited hyaline degeneration, inflammatory cell infiltration, neuroglial fiber, and glial cell proliferation layers from the inside to the outside. The scolex is round and is composed of the outer tissue (the body wall) and the inner furrow tissue; these tissues migrated together. Primordially differentiated sucking discs were found in one case, but no hooklets were found. The inner scolex tissue was folded like a paper flower. The severity of intraocular disease is closely correlated with the pathophysiological processes of the cysticercus worm. Pathological examination of the intraocular lesions can help to evaluate the course of the disease as well as to provide a scientific basis for effective antiparasitic medication.
authors.affiliation: Department of Ophthalmology, Red Cross Hospital of Yunnan, Kunming, China.
authors.forename: Juan-Juan
authors.initials: JJ
authors.lastname: Li
authors.forename: Li-Wei
authors.initials: LW
authors.lastname: Zhang
authors.forename: Hua
authors.initials: H
authors.lastname: Li
authors.forename: Zhu-Lin
authors.initials: ZL
authors.lastname: Hu
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002648:Child; D002681:China; D003551:Cysticercosis / Q000175:diagnosis* / Q000469:parasitology / Q000473:pathology*; D009877:Endophthalmitis / Q000175:diagnosis* / Q000469:parasitology / Q000473:pathology*; D005123:Eye / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D041201:Taenia solium / Q000302:isolation & purification*; D014463:Ultrasonography; D055815:Young Adult
keywords: Taenia solium metacestode; cysticercosis; cysticercus; intraocular