title: Perspective on the Martini model.
abstract: The Martini model, a coarse-grained force field for biomolecular simulations, has found a broad range of applications since its release a decade ago. Based on a building block principle, the model combines speed and versatility while maintaining chemical specificity. Here we review the current state of the model. We describe recent highlights as well as shortcomings, and our ideas on the further development of the model.
authors.affiliation: Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 7, 9747AG Groningen, The Netherlands. s.j.marrink@rug.nl
authors.forename: Siewert J
authors.initials: SJ
authors.lastname: Marrink
authors.forename: D Peter
authors.initials: DP
authors.lastname: Tieleman
mesh_terms: D004337:Drug Carriers / Q000737:chemistry; D018014:Gene Transfer Techniques; D008051:Lipid Bilayers / Q000737:chemistry; D008074:Lipoproteins / Q000737:chemistry / Q000378:metabolism; D008565:Membrane Proteins / Q000737:chemistry / Q000378:metabolism; D008962:Models, Theoretical; D056004:Molecular Dynamics Simulation; D053758:Nanoparticles / Q000737:chemistry; D010455:Peptides / Q000737:chemistry / Q000378:metabolism
chemical_list: D004337:Drug Carriers; D008051:Lipid Bilayers; D008074:Lipoproteins; D008565:Membrane Proteins; D010455:Peptides