title: Pharmacologic issues of antiretroviral agents and immunosuppressive regimens in HIV-infected solid organ transplant recipients.
abstract: HIV-positive patients are now undergoing solid organ transplantation at increasing rates, with successful outcomes. Transplantation in this unique patient population presents new challenges in the postoperative management of both antiretroviral regimens and immunosuppressive regimens. This review highlights the drug-drug interactions between commonly used immunosuppressive and antiretroviral agents. As more antiretroviral regimens are cautiously initiated in the posttransplant period, further research is needed to identify drug-drug interactions to minimize toxicities and improve long-term survival and graft function.
authors.affiliation: Georgetown University Medical Center, Division of Infectious Diseases, Department of Medicine, Washington, DC 20007-2113, USA. jxprime@gmail.com
authors.forename: Jennifer
authors.initials: J
authors.lastname: Primeggia
authors.forename: Joseph G
authors.initials: JG
authors.lastname: Timpone
authors.forename: Princy N
authors.initials: PN
authors.lastname: Kumar
mesh_terms: D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D004347:Drug Interactions; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016377:Organ Transplantation
chemical_list: D044966:Anti-Retroviral Agents; D007166:Immunosuppressive Agents