title: Prostate cancer: a hospital-based survival study from Mumbai, India.
abstract: BACKGROUND
  Prostate cancer is common in elderly men, especially in western countries, and incidences are rising in low-risk populations as well. In India, the age-standardized rates vary between registries. Under these circumstances we have estimated the survival of prostate cancer patients based on age, family history, diabetes, hypertension, tobacco habit, clinical extent of disease (risk group) and treatment received.
  
  
  METHODS
  The present retrospective study was carried out at the Tata Memorial Hospital (TMH), Mumbai, India. During years 1999-2002, some 850 prostate cancer cases, including 371 new cases, treated in TMH were considered as eligible entrants for the study. Five-year survival rates using actuarial and loss-adjusted (LAR) method were estimated.
  
  
  RESULTS
  The patient population was distributed uniformly over the three age groups. A larger proportion of the patients were diagnosed at 'metastatic stage' and hormone treatment was most common. 20% patients had history of diabetes and 40% with hypertension. The 5-year overall survival rate was 64%. Survival was 55%, 74% and 52% for ' <59 years', '60-69 years' and ' >70 years' respectively. Non-diabetic (70%), hypertensive (74%), with family history (80%) of cancer, with localized-disease (91%) and treated with surgery, either alone or in combination, (91%) had better survival.
  
  
  CONCLUSIONS
  The present study showed that prostate cancer patients with localized disease at diagnosis experience a better outcome. Local treatment with either surgery or radiation achieves a reasonable outcome in prostate cancer patients. A detailed study will help in understanding the prognostic indicators for survival especially with the newer treatment technologies available now.
authors.affiliation: Department of Cancer Registry, Biostatistics and Epidemiology, Tata Memorial Hospital, Mumbai, India. bganeshbala07@yahoo.com
authors.forename: Ganesh
authors.initials: G
authors.lastname: Balasubramaniam
authors.forename: Sanjay
authors.initials: S
authors.lastname: Talole
authors.forename: Umesh
authors.initials: U
authors.lastname: Mahantshetty
authors.forename: Sushama
authors.initials: S
authors.lastname: Saoba
authors.forename: Shyam
authors.initials: S
authors.lastname: Shrivastava
mesh_terms: D000368:Aged; D015897:Comorbidity; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000453:epidemiology / Q000401:mortality* / Q000473:pathology; D012189:Retrospective Studies; D015996:Survival Rate