title: A new isoflavonoid glycoside from the aerial parts of Trachelospermum jasminoides.
abstract: OBJECTIVE
  To study the chemical constituents from the aerial parts of Trachelospermum jasminoides.
  
  
  METHODS
  Compounds were isolated by various chromatographic methods and their structures were elucidated on the basis of spectral techniques. In addition, the inhibitory activity against HepG2 and HL-60 of compound 1 was evaluated.
  
  
  RESULTS
  Five compounds were isolated and identified as 3', 7-dimethoxyisoflavanone-4', 5-di-O-β-D-glucopyranoside (1), tracheloside (2), nortrachelogenin 5'-C-β-glucopyranoside (3), luteolin-4'-O-β-D-rutinoside (4), and luteolin-7-O-β-D-glucopyranoside (5).
  
  
  CONCLUSIONS
  Compound 1 is a new isoflavonoid glycoside. It showed weak inhibitory activity against HepG2 and HL-60 cancer cells with IC50 values of 131.5 and 58.2 μmol·L(-1), respectively.
authors.affiliation: Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.forename: Zhi-Qi
authors.initials: ZQ
authors.lastname: Yin
authors.forename: Jing-Yu
authors.initials: JY
authors.lastname: Liang
mesh_terms: D029062:Apocynaceae / Q000737:chemistry*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D005419:Flavonoids; D006027:Glycosides; D010936:Plant Extracts