title: Temperature-responsive enzyme-polymer nanoconjugates with enhanced catalytic activities in organic media.
abstract: A general approach for preparing enzyme-polymer nanoconjugates that respond to temperature in organic media is presented. These nanoconjugates readily dissolve in organic solvents for homogenous catalysis at 40 °C and showed greatly enhanced apparent catalytic activities. The recovery of the soluble enzyme-polymer nanoconjugates is accomplished by temperature-induced precipitation.
authors.affiliation: Department of Chemical Engineering, Tsinghua University, Beijing 100084, PR China.
authors.forename: Jingying
authors.initials: J
authors.lastname: Zhu
authors.forename: Yifei
authors.initials: Y
authors.lastname: Zhang
authors.forename: Diannan
authors.initials: D
authors.lastname: Lu
authors.forename: Richard N
authors.initials: RN
authors.lastname: Zare
authors.forename: Jun
authors.initials: J
authors.lastname: Ge
authors.forename: Zheng
authors.initials: Z
authors.lastname: Liu
mesh_terms: D055162:Biocatalysis; D002175:Candida / Q000201:enzymology; D004800:Enzymes, Immobilized / Q000737:chemistry / Q000378:metabolism; D057927:Hydrophobic and Hydrophilic Interactions; D008049:Lipase / Q000737:chemistry* / Q000378:metabolism; D058726:Nanoconjugates / Q000737:chemistry*; D020442:Poloxamer / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D011126:Polypropylenes / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D013696:Temperature
chemical_list: D004800:Enzymes, Immobilized; D058726:Nanoconjugates; D011108:Polymers; D011126:Polypropylenes; D012997:Solvents; D020442:Poloxamer; D008049:Lipase