title: Programmable fractal nanostructured interfaces for specific recognition and electrochemical release of cancer cells.
abstract: Topographic recognition of cancer cells is triggered by fractal gold nanostructures (FAuNSs), leading to dramatically enhanced recognition capability and efficient release of cancer cells with little damage. The unique characteristic of FAuNSs is the similar fractal dimension of their surface and that of a cancer cell. The design of fractal nanostructures will open up opportunities for functional design of bio-interfaces for highly efficient recognition and release of disease-related rare cells, which will improve detection in a clinical environment.
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China; University of the Chinese Academy of Sciences, Beijing 100049, P. R. China.
authors.forename: Pengchao
authors.initials: P
authors.lastname: Zhang
authors.forename: Li
authors.initials: L
authors.lastname: Chen
authors.forename: Tailin
authors.initials: T
authors.lastname: Xu
authors.forename: Hongliang
authors.initials: H
authors.lastname: Liu
authors.forename: Xueli
authors.initials: X
authors.lastname: Liu
authors.forename: Jingxin
authors.initials: J
authors.lastname: Meng
authors.forename: Gao
authors.initials: G
authors.lastname: Yang
authors.forename: Lei
authors.initials: L
authors.lastname: Jiang
authors.forename: Shutao
authors.initials: S
authors.lastname: Wang
mesh_terms: D045744:Cell Line, Tumor; D004563:Electrochemistry; D017709:Fractals; D006046:Gold / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D053768:Metal Nanoparticles; D036103:Nanotechnology / Q000379:methods*; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology*
chemical_list: D006046:Gold
keywords: cancer cell recognition; cell release; electrochemistry; fractal nanostructure