title: Nicked-sleeve interface for two-dimensional capillary electrophoresis.
abstract: We report an improved interface for two-dimensional capillary electrophoresis. This interface is based on capillary tubing and a Plexiglas chip, both of which were milled using a micro-dicing saw. The interface was evaluated and compared to a traditional interface design for both pseudo one-dimensional and two-dimensional capillary electrophoresis. We observe less than 70% transfer efficiency for the traditional design and greater than 90% transfer efficiency with this new interface.
authors.affiliation: Department of Chemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
authors.forename: Ryan J
authors.initials: RJ
authors.lastname: Flaherty
authors.forename: Bonnie J
authors.initials: BJ
authors.lastname: Huge
authors.forename: Spencer M
authors.initials: SM
authors.lastname: Bruce
authors.forename: Oluwatosin O
authors.initials: OO
authors.lastname: Dada
authors.forename: Norman J
authors.initials: NJ
authors.lastname: Dovichi
mesh_terms: D019075:Electrophoresis, Capillary / Q000295:instrumentation*; D004867:Equipment Design; D055616:Microtechnology