title: Pericarditis mediated by respiratory syncytial virus in a hematopoietic stem cell transplant patient.
abstract: We describe a case of pericarditis and large pericardial effusion in a 63-year-old African-American man undergoing autologous hematopoietic stem cell transplant for multiple myeloma. Pericardial tissue biopsy demonstrated fibrinous pericarditis, and immunohistochemistry stains were positive for respiratory syncytial virus. The patient improved with oral ribavirin and intravenous immune globulin infusions.
authors.affiliation: Department of Medicine, Division of Infectious Diseases and International Health, Duke University Medical Center, Durham, North Carolina 27710, USA. matthew.rubach@duke.edu
authors.forename: M P
authors.initials: MP
authors.lastname: Rubach
authors.forename: E N
authors.initials: EN
authors.lastname: Pavlisko
authors.forename: J R
authors.initials: JR
authors.lastname: Perfect
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000628:therapy; D010490:Pericardial Effusion / Q000188:drug therapy; D010493:Pericarditis / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology*; D018113:Respiratory Syncytial Virus, Human / Q000302:isolation & purification*; D012254:Ribavirin
chemical_list: D000998:Antiviral Agents; D016756:Immunoglobulins, Intravenous; D012254:Ribavirin
keywords: IVIg; hematopoietic stem cell transplant; multiple myeloma; pericarditis; respiratory syncytial virus; ribavirin