title: HPLC-based metabolic profiling and quality control of leaves of different Panax species.
abstract: Leaves from Panax ginseng Meyer (Korean origin and Chinese origin of Korean ginseng) and P. quinquefolius (American ginseng) were harvested in Haenam province, Korea, and were analyzed to investigate patterns in major metabolites using HPLC-based metabolic profiling. Partial least squares discriminant analysis (PLS-DA) was used to analyze the HPLC chromatogram data. There was a clear separation between Panax species and/or origins from different countries in the PLS-DA score plots. The ginsenoside compounds of Rg1, Re, Rg2, Rb2, Rb3, and Rd in Korean leaves were higher than in Chinese and American ginseng leaves, and the Rb1 level in P. quinquefolius leaves was higher than in P. ginseng (Korean origin or Chinese origin). HPLC chromatogram data coupled with multivariate statistical analysis can be used to profile the metabolite content and undertake quality control of Panax products.
authors.affiliation: Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration, Eumseong 369-873, Korea.
authors.forename: Seung-Ok
authors.initials: SO
authors.lastname: Yang
authors.forename: Sang Won
authors.initials: SW
authors.lastname: Lee
authors.forename: Young Ock
authors.initials: YO
authors.lastname: Kim
authors.forename: Sang-Hyun
authors.initials: SH
authors.lastname: Sohn
authors.forename: Young Chang
authors.initials: YC
authors.lastname: Kim
authors.forename: Dong Yoon
authors.initials: DY
authors.lastname: Hyun
authors.forename: Yoon Pyo
authors.initials: YP
authors.lastname: Hong
authors.forename: Yu Su
authors.initials: YS
authors.lastname: Shin
keywords: Ginsenosides; HPLC; Metabolic profiling; Panax leaves; Quality control