title: PET/MR in prostate cancer: technical aspects and potential diagnostic value.
abstract: PET/MR is a new multimodal imaging technique that is expected to improve diagnostic performance of imaging in conditions in which assessment of changes in soft tissue is important such as prostate cancer. Despite substantial changes in PET technology compared to PET/CT, initial studies have demonstrated that integrated PET/MR provides comparable image quality to that of PET/CT, retaining PET quantification efficacy. In this review we briefly describe technological changes compared to PET/CT that made integrated PET/MR possible, propose acquisition protocols for evaluation of prostate cancer with this new multimodal approach, present initial results concerning the application of PET/MR in prostate cancer, and outline the potential for further clinical applications, focusing on potential incremental value compared to present diagnostic performance.
authors.affiliation: Klinik für Nuklearmedizin, Technischen Universität München, Ismaninger Str 22, 81675 München, Germany. msouvatz@yahoo.de
authors.forename: Michael
authors.initials: M
authors.lastname: Souvatzoglou
authors.forename: Matthias
authors.initials: M
authors.lastname: Eiber
authors.forename: Axel
authors.initials: A
authors.lastname: Martinez-Moeller
authors.forename: Sebastian
authors.initials: S
authors.lastname: Fürst
authors.forename: Konstantin
authors.initials: K
authors.lastname: Holzapfel
authors.forename: Tobias
authors.initials: T
authors.lastname: Maurer
authors.forename: Sibylle
authors.initials: S
authors.lastname: Ziegler
authors.forename: Stephan
authors.initials: S
authors.lastname: Nekolla
authors.forename: Markus
authors.initials: M
authors.lastname: Schwaiger
authors.forename: Ambros J
authors.initials: AJ
authors.lastname: Beer
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D064847:Multimodal Imaging / Q000379:methods*; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D011471:Prostatic Neoplasms / Q000175:diagnosis*