title: Management of recurrent hepatitis C in orthotopic liver transplant recipients.
abstract: End-stage liver disease and hepatocellular carcinoma from chronic hepatitis C are the most common indications for orthotopic liver transplantation and the incidence of both are projected to increase over the next decade. Recurrent hepatitis C virus infection of the allograft is associated with an accelerated progression to cirrhosis, graft loss, and death. This article presents an overview of the natural history of hepatitis C virus recurrence in liver transplant recipients and guidance on optimal management strategies.
authors.affiliation: Department of Infectious Diseases, Georgetown University Hospital, Washington, DC 20007, USA. Geeta.S.Karnik@gunet.georgetown.edu
authors.forename: Geeta S
authors.initials: GS
authors.lastname: Karnik
authors.forename: Kirti
authors.initials: K
authors.lastname: Shetty
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D019698:Hepatitis C, Chronic / Q000188:drug therapy* / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation; D055502:Secondary Prevention; D014180:Transplantation
chemical_list: D000998:Antiviral Agents