title: The extension of a DNA double helix by an additional Watson-Crick base pair on the same backbone.
abstract: Additional base pair: The DNA duplex can be extended with an additional Watson-Crick base pair on the same backbone by the use of double-headed nucleotides. These also work as compressed dinucleotides and form two base pairs with cognate nucleobases on the opposite strand.
authors.affiliation: Nucleic Acid Center, Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, 5230 Odense M, Denmark.
authors.forename: Pawan
authors.initials: P
authors.lastname: Kumar
authors.forename: Pawan K
authors.initials: PK
authors.lastname: Sharma
authors.forename: Charlotte S
authors.initials: CS
authors.lastname: Madsen
authors.forename: Michael
authors.initials: M
authors.lastname: Petersen
authors.forename: Poul
authors.initials: P
authors.lastname: Nielsen
mesh_terms: D020029:Base Pairing; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D056004:Molecular Dynamics Simulation; D009690:Nucleic Acid Conformation; D009711:Nucleotides / Q000737:chemistry; D013816:Thermodynamics
chemical_list: D009711:Nucleotides; D004247:DNA