title: Percutaneous transluminal renal angioplasty application effect on renal function in patients with renal artery stenosis - a case report on 4 patients.
abstract: BACKGROUND
  Renal artery stenosis (RAS) is narrowing of one or both renal arteries or their branches. Clinically sig nificant stenosis involves narrowing of the lumen, which is approximately 80%. The two most common causes of its occurrence are atherosclerosis and fibromuscular dyspla sia. Percutaneous transluminal renal angioplasty (PTRA) with stent implantation is an effective treatment modality that leads to lower blood pressure and improvement of kidney function.
  
  
  METHODS
  We presented 4 patients with significant stenosis of one or both renal arteries fol lowed by the development of arterial hypertension and re nal insufficiency. The causes of RAS were atherosclerosis in two patients and fibromuscular dysplasia in one patient. One of the patients had renal artery stenosis of trans planted kidney that developed 9 month after transplanta tion. In all the patients, in addition to clinical signs, dop pler screening suspected the existence of significant renal artery stenosis. The definitive diagnosis was made by ap plying computed tomographic angiography (CTA) of renal arteries in 3 of the patients and in 1 patient by percutaneus selective angiography. All the patients were treated by ap plication of PTRA with stent implantation followed by improvement/normalization of blood pressure and kidney function.
  
  
  CONCLUSIONS
  Application of PTRA with stent implantation is an effective treatment of significant steno sis of one or both renal arteries followed by renal insuffi ciency.
authors.affiliation: Clinic of Nephrology, Military Medical Academy, Belgrade, Serbia. mirjana.mijuskovic@gmail.com
authors.forename: Mirjana
authors.initials: M
authors.lastname: Mijusković
authors.forename: Neven
authors.initials: N
authors.lastname: Vavić
authors.forename: Sinisa
authors.initials: S
authors.lastname: Rusović
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Ignjatović
authors.forename: Katarina
authors.initials: K
authors.lastname: Obrencević
authors.forename: Milorad
authors.initials: M
authors.lastname: Radojević
authors.forename: Zoran
authors.initials: Z
authors.lastname: Kovacević
authors.forename: Zoran
authors.initials: Z
authors.lastname: Cukić
authors.forename: Marijana
authors.initials: M
authors.lastname: Petrović
authors.forename: Dejan
authors.initials: D
authors.lastname: Pilcević
authors.forename: Jelena Tadić
authors.initials: JT
authors.lastname: Pilcević
authors.forename: Brankica
authors.initials: B
authors.lastname: Terzić
mesh_terms: D000328:Adult; D017130:Angioplasty; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*