title: Synthesis of 6-(trifluoromethyl)phenanthridines via palladium-catalyzed tandem Suzuki/C-H arylation reactions.
abstract: A palladium-catalyzed tandem Suzuki/C-H arylation reaction of N-aryltrifluoroacetimidoyl chlorides with arylboronic acids has been developed. A variety of 6-(trifluoromethyl)phenanthridines were prepared in moderate to excellent yields from N-(2-bromophenyl)trifluoroacetimidoyl chlorides which can be conveniently prepared from 2-bromoaniline derivatives.
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China.
authors.forename: Wen-Ying
authors.initials: WY
authors.lastname: Wang
authors.forename: Xia
authors.initials: X
authors.lastname: Feng
authors.forename: Bo-Lun
authors.initials: BL
authors.lastname: Hu
authors.forename: Chen-Liang
authors.initials: CL
authors.lastname: Deng
authors.forename: Xing-Guo
authors.initials: XG
authors.lastname: Zhang
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry; D001897:Boronic Acids / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D010617:Phenanthridines / Q000138:chemical synthesis*
chemical_list: D000814:Aniline Compounds; D001897:Boronic Acids; D010617:Phenanthridines; C075716:3-bromoaniline; D010165:Palladium