title: Candida parapsilosis endocarditis on a prosthetic aortic valve with unclear echocardiographic features.
abstract: Fungal endocarditis is rare in comparison with bacterial endocarditis and is associated with a poor prognosis. Despite the proven reliability of echocardiography, false negatives are not uncommon and may influence the therapeutic strategy, as some reports have supported the efficacy of antifungal treatment alone. We report on a case of bioprosthetic aortic valve Candida parapsilosis endocarditis without typical echocardiograhy findings, which we treated with both antifungal and surgical therapy.
authors.affiliation: Department of Cardiac Surgery, Policlinico Tor Vergata, Tor Vergata University of Rome, Rome, Italy. mmvondocarlo@yahoo.fr
authors.forename: Charles Mve
authors.initials: CM
authors.lastname: Mvondo
authors.forename: Francesca
authors.initials: F
authors.lastname: D'Auria
authors.forename: Pasquale
authors.initials: P
authors.lastname: Sordillo
authors.forename: Antonio
authors.initials: A
authors.lastname: Pellegrino
authors.forename: Massimo
authors.initials: M
authors.lastname: Adreoni
authors.forename: Luigi
authors.initials: L
authors.lastname: Chiariello
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000601:surgery*; D002177:Candidiasis / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D003131:Combined Modality Therapy; D020878:Device Removal; D018618:Echocardiography, Doppler, Color; D017548:Echocardiography, Transesophageal; D004696:Endocarditis / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects* / Q000295:instrumentation; D006801:Humans; D011237:Predictive Value of Tests; D016459:Prosthesis-Related Infections / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D012086:Reoperation; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents