title: Basic cancer research is essential for the success of personalised medicine.
abstract: The last decade has witnessed significant progress in cancer understanding and therapy: we can now identify the genetic drivers of individual tumours, and tailor drugs able to specifically intercept the driver mutations. While all agree that personalised cancer medicine is a clear outcome of the resources dedicated to cancer research over the last 50 years, some critics question the necessity for continuous investments in sub-fields other than clinical research and drug development. Herein, scientists from the European Association for Cancer Research (EACR) argue that the new ways to diagnose and treat cancer present important and hitherto unaddressed challenges for fundamental research of cancer. Allocating the resources needed for basic studies will likely fuel the next wave of achievements in the long way to conquer cancer.
authors.affiliation: Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel. Yosef.Yarden@weizmann.ac.il
authors.forename: Yosef
authors.initials: Y
authors.lastname: Yarden
authors.forename: Carlos
authors.initials: C
authors.lastname: Caldas
authors.forename: Carlos
authors.initials: C
authors.lastname: Caldes
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000379:methods* / Q000639:trends; D019008:Drug Resistance, Neoplasm / Q000187:drug effects / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D009154:Mutation; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics; D057285:Precision Medicine / Q000379:methods* / Q000639:trends
keywords: Cancer