title: An uncommon case of an adult with del(5)(q) in acute lymphoblastic leukemia.
abstract: Del(5)(q) is a common chromosomal abnormality with favourable prognosis in Myelodysplastic Syndrome (MDS) and Acute myeloid leukemia (AML). However, del(5)(q) is also seen rarely in Acute lymphoblastic leukemia (ALL) and its significance remains poorly understood. We present here, a case report of diagnosis of an adult 75 year old patient of ALL with a cytogenetic abnormality of del(5)(q32). His clinical features, morphology and immunophenotyping findings were suggestive of T-ALL. Relevant literature has been reviewed and discussed.
authors.affiliation: Department of Molecular Biology, Triesta Reference Laboratory, HealthCare Global Enterprises Ltd, Bangalore, India.
authors.forename: E
authors.initials: E
authors.lastname: Venkataswamy
authors.forename: Ashwini R
authors.initials: AR
authors.lastname: Nargund
authors.forename: Shilpa
authors.initials: S
authors.lastname: Prabhudesai
authors.forename: Geeta V
authors.initials: GV
authors.lastname: Patil
authors.forename: Rao J
authors.initials: RJ
authors.lastname: Chandra
authors.forename: Vidya H
authors.initials: VH
authors.lastname: Veldore
authors.forename: Shekar
authors.initials: S
authors.lastname: Patil
authors.forename: Amit
authors.initials: A
authors.lastname: Verma
authors.forename: Rashmita
authors.initials: R
authors.lastname: Sahoo
authors.forename: B S
authors.initials: BS
authors.lastname: Ajaikumar
authors.lastname: Prasannakumari
keywords: Acute lymphoblastic leukemia; del(5)(q); rare abnormality