title: Insect biotechnology: controllable replacement of disease vectors.
abstract: To fight human vector-borne diseases, first releases of sterile transgenic mosquitoes have been performed. Someday, disease-refractory mosquitoes will replace wild types to stop transmission. For such population replacements, gene drive mechanisms must be established that allow local confinement and reversibility.
authors.affiliation: Department of Developmental Biology, Johann-Friedrich-Blumenbach Institute of Zoology and Anthropology, GZMB, Georg-August-Universität Göttingen, Ernst-Caspari-Haus, Justus-von-Liebig-Weg 11, 37077 Göttingen, Germany. ewimmer@gwdg.de
authors.forename: Ernst A
authors.initials: EA
authors.lastname: Wimmer
mesh_terms: D000818:Animals; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D017344:Genes, Insect; D005813:Genes, Synthetic; D008297:Male; D019076:Transgenes