title: Malignant lymphoma of the oral cavity and the maxillofacial region: overall survival prognostic factors.
abstract: OBJECTIVE
  To identify the overall survival and prognostic factors of malignant lymphoma of the oral cavity and the maxillofacial region.
  
  
  METHODS
  Clinical records data were obtained in order to determine overall survival at 2 and 5 years, the individual survival percentage of each possible prognostic factor with the actuarial technique, and the survival regarding the possible prognostic factors with the actuarial technique and the Log-rank and Cox's regression tests.
  
  
  RESULTS
  Of 151 subjects, an overall survival was 60% at 2 years, and 45% at 5 years. The multivariate analysis demonstrated statistically significant differences for clinical stage (p=0.002), extranodal involvement (p=0.030), presence of human immunodeficiency virus (p=0.032), and presence of Epstein-Barr virus (p=0.010).
  
  
  CONCLUSIONS
  The advanced clinical stage and the larger number of involved extranodular sites are related to a lower overall survival, as well as, the presence of previous infections such as the human immunodeficiency and the Epstein-Barr virus.
authors.affiliation: Faculty of Dentistry of the University de San Martín de Porres, USMP, Lima, Peru. janetguevara7@hotmail.com
authors.forename: Janet-Ofelia
authors.initials: JO
authors.lastname: Guevara-Canales
authors.forename: Rafael
authors.initials: R
authors.lastname: Morales-Vadillo
authors.forename: Sonia-Julia
authors.initials: SJ
authors.lastname: Sacsaquispe-Contreras
authors.forename: Carlos
authors.initials: C
authors.lastname: Barrionuevo-Cornejo
authors.forename: Jaime
authors.initials: J
authors.lastname: Montes-Gil
authors.forename: Carlos-Enrique
authors.initials: CE
authors.lastname: Cava-Vergiú
authors.forename: Fernando-Augusto
authors.initials: FA
authors.lastname: Soares
authors.forename: Henrique-Duque-de-Miranda
authors.initials: HD
authors.lastname: Chaves-Netto
authors.forename: Maria-das-Graças-Afonso-Miranda
authors.initials: MD
authors.lastname: Chaves
mesh_terms: D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000401:mortality*; D008297:Male; D008441:Maxillary Neoplasms / Q000401:mortality*; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000401:mortality*; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors