title: The influence of implant geometry and surface composition on bone response.
abstract: OBJECTIVE
  The implant design and surface modification are independent conditions that can alter the implant bone response. The objective of this study is to compare the bone response to roughened tapered and cylindrical screw-type implants with and without hydroxyapatite (HA) surface coating in the femoral trabecular bone of rabbits.
  
  
  METHODS
  Thirty-two implants (8 × 3.5 mm) consisting of four different types (eight implants in each group), that is, tapered implants, cylindrical implants, HA-coated tapered implants, and HA-coated cylindrical implants were installed in the femoral condyle of 16 rabbits. After 8 weeks of healing, the femoral condyles were retrieved and studied histologically. The bone-to-implant contact percentage was assessed and analyzed statistically.
  
  
  RESULTS
  The histomorphometric analysis revealed that the bone-to-implant contact (BIC) values seemed to be higher for HA-coated tapered implants (65.62 ± 13.02) followed by cylindrical non-coated implants. All four types of implants showed wide distribution of BIC with no statistical significance between different types of implants.
  
  
  CONCLUSIONS
  It can be concluded that under the current experimental conditions, implant design and surface composition had little effect on the bone-to-implant interface.
authors.affiliation: Department of Prosthetic Dental Science, College of Dentistry, King Saud University, Riyadh, Saudi Arabia; Dental Implant and Osseointegration Research Chair (DIORC), College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Abdullah
authors.initials: A
authors.lastname: AlFarraj Aldosari
authors.forename: Sukumaran
authors.initials: S
authors.lastname: Anil
authors.forename: Mohammed
authors.initials: M
authors.lastname: Alasqah
authors.forename: Khalid A
authors.initials: KA
authors.lastname: Al Wazzan
authors.forename: Samer A
authors.initials: SA
authors.lastname: Al Jetaily
authors.forename: John A
authors.initials: JA
authors.lastname: Jansen
mesh_terms: D000818:Animals; D015921:Dental Implants; D017267:Dental Prosthesis Design; D017268:Dental Prosthesis Retention; D017886:Durapatite / Q000494:pharmacology; D005269:Femur / Q000601:surgery; D020007:Implants, Experimental; D011817:Rabbits; D013499:Surface Properties; D014025:Titanium
chemical_list: D015921:Dental Implants; D017886:Durapatite; D014025:Titanium
keywords: calcium phosphate coatings; cylindrical; dental implant; histomorphometry; implant design; osseointegration; surface treatment; tapered