title: Organocatalytic asymmetric desymmetrization: efficient construction of spirocyclic oxindoles bearing a unique all-carbon quaternary stereogenic center via sulfa-Michael addition.
abstract: An unprecedented enantioselective desymmetrization of spiro cyclohexadienone oxindoles has been developed successfully via organocatalyzed asymmetric SMA, which provides facile access to spirocyclic oxindoles bearing a unique all-carbon quaternary stereogenic center with excellent levels of stereoselectivity.
authors.affiliation: College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Yao
authors.forename: Kang
authors.initials: K
authors.lastname: Liu
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Tao
authors.forename: Guo-Fu
authors.initials: GF
authors.lastname: Qiu
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhou
authors.forename: Chun-Jiang
authors.initials: CJ
authors.lastname: Wang
mesh_terms: D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D018360:Crystallography, X-Ray; D053138:Cyclohexenes / Q000737:chemistry; D007211:Indoles / Q000737:chemistry*; D008968:Molecular Conformation; D000078183:Oxindoles; D013141:Spiro Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D053138:Cyclohexenes; D007211:Indoles; D000078183:Oxindoles; D013141:Spiro Compounds; C048401:1,4-cyclohexadiene; C022960:2-oxindole; D002244:Carbon