title: The dynamics of HCF-1 modulation of herpes simplex virus chromatin during initiation of infection.
abstract: Successful infection of herpes simplex virus is dependent upon chromatin modulation by the cellular coactivator host cell factor-1 (HCF-1). This review focuses on the multiple chromatin modulation components associated with HCF-1 and the chromatin-related dynamics mediated by this coactivator that lead to the initiation of herpes simplex virus (HSV) immediate early gene expression.
authors.affiliation: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bld. 33, 33 North Drive, Bethesda, MD 20892, USA. jvogel@niaid.nih.gov
authors.forename: Jodi L
authors.initials: JL
authors.lastname: Vogel
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Kristie
mesh_terms: D002843:Chromatin / Q000378:metabolism*; D015967:Gene Expression Regulation, Viral; D051863:Host Cell Factor C1 / Q000378:metabolism*; D054884:Host-Pathogen Interactions; D006801:Humans; D018139:Simplexvirus / Q000502:physiology*; D014779:Virus Replication
chemical_list: D002843:Chromatin; C497692:HCFC1 protein, human; D051863:Host Cell Factor C1