title: The growing role of eicosanoids in tissue regeneration, repair, and wound healing.
abstract: Tissue repair and regeneration are essential processes in maintaining tissue homeostasis, especially in response to injury or stress. Eicosanoids are ubiquitous mediators of cell proliferation, differentiation, and angiogenesis, all of which are important for tissue growth. Eicosanoids regulate the induction and resolution of inflammation that accompany the tissue response to injury. In this review, we describe how this diverse group of molecules is a key regulator of tissue repair and regeneration in multiple organ systems and biologic contexts.
authors.affiliation: Vascular Biology Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. brian.kalish@childrens.harvard.edu
authors.forename: Brian T
authors.initials: BT
authors.lastname: Kalish
authors.forename: Mark W
authors.initials: MW
authors.lastname: Kieran
authors.forename: Mark
authors.initials: M
authors.lastname: Puder
authors.forename: Dipak
authors.initials: D
authors.lastname: Panigrahy
mesh_terms: D000818:Animals; D016723:Bone Remodeling / Q000502:physiology*; D002454:Cell Differentiation; D049109:Cell Proliferation; D015777:Eicosanoids / Q000378:metabolism*; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D008115:Liver Regeneration / Q000502:physiology*; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism*; D014945:Wound Healing / Q000502:physiology*; D014947:Wounds and Injuries / Q000378:metabolism*
chemical_list: D015777:Eicosanoids