title: Parental use of antidepressant medication and family type in the risk for incident psychiatric morbidity in offspring.
abstract: BACKGROUND
  Maternal depression increases the risk for psychiatric morbidity in offspring but the effects of paternal depression and family type are less studied.
  
  
  METHODS
  We assessed the effects of parental antidepressant use on offspring psychiatric morbidity in various family settings.
  
  
  RESULTS
  Our register-based study followed 132637 children for incident psychiatric morbidity in 1998-2003. The highest risk for psychiatric morbidity was in children living with both parents on antidepressants or with a lone parent on antidepressants. We found little variation in the effects according to parental or offspring gender.
  
  
  CONCLUSIONS
  Parental depression as measured by antidepressant use, and single parenthood pose a risk for psychiatric morbidity in offspring.
authors.affiliation: Mental Health Problems and Substance Abuse Services Unit, National Institute for Health and Welfare, Helsinki, Finland. kaisla.joutsenniemi@icloud.com
authors.forename: Kaisla
authors.initials: K
authors.lastname: Joutsenniemi
authors.forename: Heta
authors.initials: H
authors.lastname: Moustgaard
authors.forename: Pekka
authors.initials: P
authors.lastname: Martikainen
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use*; D002648:Child; D016241:Child of Impaired Parents / Q000523:psychology* / Q000706:statistics & numerical data; D003863:Depression / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D005190:Family / Q000523:psychology*; D005260:Female; D005387:Finland / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008297:Male; D017533:Marital Status / Q000706:statistics & numerical data; D009017:Morbidity; D010290:Parents / Q000523:psychology*; D016012:Poisson Distribution; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D000928:Antidepressive Agents
keywords: EPIDEMIOLOGY; MATERNAL & CHILD CG; MENTAL HEALTH