title: In-vivo expansion of autologous limbal stem cell using simple limbal epithelial transplantation for treatment of limbal stem cell deficiency.
abstract: A 20-year-old man from Bangladesh suffered accidental alkali injury to his right eye in May 2010 leading to total limbal stem cell deficiency. An amniotic membrane graft was performed 5 days after the accident and the patient presented to our institute 6 months later. On ocular examination, his best corrected visual acuity (BCVA) was 20/50 with a 360° pannus at the periphery and central area was spared but had stromal scarring. He underwent simple limbal epithelial transplantation (SLET) taking a limbal biopsy from his left eye and was prescribed steroid and antibiotic eye drops postoperatively as per the standard regimen. At 2 year follow-up, the patient's ocular surface is stable with improvement in  BCVA to 20/25 post-SLET.
authors.affiliation: Cornea and Anterior Segment Service, LV Prasad Eye Institute, Kallam Anji Reddy Campus, L V Prasad Marg, Banjara Hills, Hyderabad, Andhra Pradesh, India.
authors.forename: Ikeda
authors.initials: I
authors.lastname: Lal
authors.forename: Bhavik Uttam
authors.initials: BU
authors.lastname: Panchal
authors.forename: Sayan
authors.initials: S
authors.lastname: Basu
authors.forename: Virender S
authors.initials: VS
authors.lastname: Sangwan
mesh_terms: D000328:Adult; D000650:Amnion / Q000637:transplantation; D001706:Biopsy; D002057:Burns, Chemical / Q000150:complications / Q000473:pathology / Q000601:surgery*; D003319:Corneal Stroma / Q000473:pathology; D019573:Epithelium, Corneal / Q000473:pathology / Q000637:transplantation*; D005126:Eye Burns / Q000150:complications / Q000473:pathology / Q000601:surgery*; D006801:Humans; D016850:Limbus Corneae / Q000166:cytology / Q000473:pathology / Q000601:surgery*; D008297:Male; D033581:Stem Cell Transplantation; D013234:Stem Cells; D014182:Transplantation, Autologous; D014785:Vision, Ocular; D014792:Visual Acuity; D055815:Young Adult