title: Preclinical investigations for thrombectomy devices--does it translate to humans?
authors.affiliation: Department of Radiology, New England Center for Stroke Research, University of Massachusetts, 55 Lake Ave North, Worcester, MA 01655, USA. matthew.gounis@umassmed.edu
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Gounis
authors.forename: Ajay K
authors.initials: AK
authors.lastname: Wakhloo
authors.forename: Ju-Yu
authors.initials: JY
authors.lastname: Chueh
mesh_terms: D015901:Angiography, Digital Subtraction; D000818:Animals; D002533:Cerebral Angiography; D002560:Cerebrovascular Circulation; D018795:Device Approval; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D008953:Models, Anatomic; D012449:Safety; D020521:Stroke / Q000601:surgery*; D017131:Thrombectomy / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods*; D014481:United States; D014486:United States Food and Drug Administration
keywords: acute ischemic stroke; clot; embolic shower; preclinical modeling; recanalization; thrombectomy