title: A sensitive, homogeneous fluorescence assay for detection of thymine DNA glycosylase activity based on exonuclease-mediated amplification.
abstract: A novel homogeneous fluorescence assay strategy for highly sensitive detection of thymine DNA glycosylase (TDG) enzyme activity based on the exonuclease-mediated signal amplification reaction was reported.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, PR China.
authors.forename: Cuihua
authors.initials: C
authors.lastname: Chen
authors.forename: Dianming
authors.initials: D
authors.lastname: Zhou
authors.forename: Hao
authors.initials: H
authors.lastname: Tang
authors.forename: Manfen
authors.initials: M
authors.lastname: Liang
authors.forename: Jianhui
authors.initials: J
authors.lastname: Jiang
mesh_terms: D002460:Cell Line; D015342:DNA Probes / Q000378:metabolism; D005092:Exonucleases / Q000378:metabolism*; D006367:HeLa Cells; D006801:Humans; D061986:MCF-7 Cells; D021141:Nucleic Acid Amplification Techniques; D013050:Spectrometry, Fluorescence; D044502:Thymine DNA Glycosylase / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D044366:Transition Temperature
chemical_list: D015342:DNA Probes; D005092:Exonucleases; D044502:Thymine DNA Glycosylase