title: [Significance of nontraumatic anal sphincter relaxation for the success of plastic and miniinvasive interventions in coloproctology].
abstract: The investigation objective was to estimate the role of nontraumatic anal sphincter (AS) stretching, as a leading factor of success in minimally invasive and/or plastic proctological interventions. One-centre randomized investigation was performed in 83 patients: In 22 of them the AS fissura was revealed (in 16), suprasphincteric fistula (in 3) and coexistent rectocele 2-3 Ap (according to POP-Q classification) with thinning of the AS anterior segment, the degree III hemorrhoids and anterior AS fissure presence. Ninety units of botulotoxin preparation (Disport) were injected between internal and external AS portions 5-15 days preoperatively. The treatment results without botulotoxin injection were compared retrospectively. After botulotoxin injection performance the AS spasm elimination was noted, leading to the pain subsiding promotion before and postoperatively in all the patients observed. The spasm elimination have permitted to escape the anal high fistula recurrence as a result of the mucosal flap shift after intraluminal closure of the fistula or because of the fistula intermuscular electrowelding "suture" rupture, also have guaranteed the plastic sutures on AS, even while the stage II-III rectocele presence, not depending of performance of its simultant surgica correction.
authors.forename: S S
authors.initials: SS
authors.lastname: Podpriatov
authors.forename: V P
authors.initials: VP
authors.lastname: Korchak
authors.forename: S V
authors.initials: SV
authors.lastname: Ivanenko
authors.forename: M I
authors.initials: MI
authors.lastname: Stupak
authors.forename: O V
authors.initials: OV
authors.lastname: Zubariev
authors.forename: V V
authors.initials: VV
authors.lastname: Ivakha
authors.forename: O V
authors.initials: OV
authors.lastname: Sydorenko
authors.forename: A A
authors.initials: AA
authors.lastname: Shtaier
authors.forename: O V
authors.initials: OV
authors.lastname: Perekhrest
authors.forename: V V
authors.initials: VV
authors.lastname: Shchepetov
authors.forename: V K
authors.initials: VK
authors.lastname: Rostunov
authors.forename: S V
authors.initials: SV
authors.lastname: Bryzhatiuk
authors.forename: V V
authors.initials: VV
authors.lastname: Kozlov
mesh_terms: D001003:Anal Canal / Q000187:drug effects* / Q000503:physiopathology; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D005260:Female; D005401:Fissure in Ano / Q000473:pathology / Q000517:prevention & control; D006484:Hemorrhoids / Q000601:surgery; D006801:Humans; D008297:Male; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D009126:Muscle Relaxation / Q000187:drug effects*; D012003:Rectal Fistula / Q000473:pathology / Q000517:prevention & control; D020047:Rectocele / Q000473:pathology / Q000517:prevention & control; D012008:Recurrence; D013035:Spasm / Q000503:physiopathology / Q000517:prevention & control*; D013518:Surgery, Plastic; D013537:Sutures; D016896:Treatment Outcome
chemical_list: D019274:Botulinum Toxins, Type A