title: Asymmetric organocatalytic cyclopropanation of cinnamone derivatives with stabilized sulfonium ylides.
abstract: A simple chiral diamine catalyst 1h was successfully applied in the asymmetric cyclopropanation of cinnamone derivatives with stabilized sulfur ylides. The desired cyclopropanation adducts were obtained in moderate yields (up to 68%) with good enantioselectivities (67-93% ee) and excellent diastereoselectivities (>95:5) under mild conditions.
authors.affiliation: Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, PR China.
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Liu
authors.forename: Shunxi
authors.initials: S
authors.lastname: Dong
authors.forename: Lili
authors.initials: L
authors.lastname: Lin
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Feng
mesh_terms: D002384:Catalysis; D003500:Cyclization; D003521:Cyclopropanes / Q000737:chemistry*; D003959:Diamines / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D013452:Sulfonium Compounds / Q000737:chemistry*
chemical_list: D003521:Cyclopropanes; D003959:Diamines; D013452:Sulfonium Compounds