title: [Q fever, a zoonosis often overlooked].
abstract: Q fever is a zoonosis caused by an intracellular Gram-negative bacteria, Coxiella burnetii. Animals are the main reservoir and transmission to men generally is occurring by inhalation of contaminated aerosols. Acute Q fever generally is benign and usually resolves spontaneously. When symptomatic, the clinical presentation typically includes one of the following three syndromes: a flu-like illness, a granulomatous hepatitis or an atypical pneumonia. Individuals presenting risk factors such as patients with valvular heart diseases and vascular prostheses, as well as pregnant women and immuno-suppressed patients represent a population at risk of chronic infection, with endocarditis as the most common clinical form.
authors.affiliation: Service des maladies infectieuses, Departement de medecine, CHUV, 1011 Lausanne.
authors.forename: J
authors.initials: J
authors.lastname: Delaloye
authors.forename: G
authors.initials: G
authors.lastname: Greub
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004318:Doxycycline / Q000627:therapeutic use; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D011778:Q Fever / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology / Q000635:transmission; D015047:Zoonoses
chemical_list: D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D006886:Hydroxychloroquine; D004318:Doxycycline