title: Human immunodeficiency virus-associated obstructive lung diseases.
abstract: In the era of effective antiretroviral therapy (ART), epidemiologic studies have found that persons infected with human immunodeficiency virus (HIV) have a higher prevalence and incidence of chronic obstructive pulmonary disease than HIV-uninfected persons. In comparison with HIV-uninfected persons and those with well-controlled HIV disease, HIV-infected persons with poor viral control or lower CD4 cell count have more airflow obstruction, a greater decline in lung function, and possibly more severe diffusing impairment. This article reviews the evidence linking HIV infection to obstructive lung disease, and discusses management issues related to the treatment of obstructive lung disease in HIV-infected patients.
authors.affiliation: Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Gingo
authors.forename: Alison
authors.initials: A
authors.lastname: Morris
authors.forename: Kristina
authors.initials: K
authors.lastname: Crothers
mesh_terms: D001249:Asthma / Q000209:etiology* / Q000628:therapy; D018791:CD4 Lymphocyte Count; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D029424:Pulmonary Disease, Chronic Obstructive / Q000209:etiology* / Q000628:therapy; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects