title: Scrub typhus and cerebrovascular injury: a phenomenon of delayed treatment?
abstract: Abstract. Three patients diagnosed with scrub typhus through serology and polymerase chain reaction tests, experienced delayed administration of effective antibiotics after the appearance of symptoms, presented with subdural hemorrhage, intracerebral hemorrhage, or cerebral infarction in the late acute phase. Orientia tsutsugamushi should be considered as a causal or provoking factor for cerebrovascular accidents in regions where scrub typhus is endemic, especially in those who receive delayed treatment.
authors.affiliation: Department of Internal Medicine, Chosun University College of Medicine,Gwang-ju, Republic of Korea.
authors.forename: Jong-Hoon
authors.initials: JH
authors.lastname: Chung
authors.forename: Na-Ra
authors.initials: NR
authors.lastname: Yun
authors.forename: Dong-Min
authors.initials: DM
authors.lastname: Kim
authors.forename: Ji-Woon
authors.initials: JW
authors.lastname: Lee
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Yoon
authors.forename: Seok-Won
authors.initials: SW
authors.lastname: Kim
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000382:microbiology; D002544:Cerebral Infarction / Q000209:etiology / Q000382:microbiology; D002561:Cerebrovascular Disorders / Q000209:etiology* / Q000382:microbiology; D057210:Delayed Diagnosis; D017809:Fatal Outcome; D005260:Female; D006408:Hematoma, Subdural / Q000209:etiology / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D059906:Neuroimaging; D012285:Orientia tsutsugamushi; D056910:Republic of Korea; D012612:Scrub Typhus / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents