title: Inhibition of Microcystis aeruginosa by the extracellular substances from an Aeromonas sp.
abstract: Growth of Microcystis aeruginosa could be inhibited significantly within 24 h by the extracellular substances prepared from Aeromonas sp. strain FM. During the treatment, the concentration of extracellular soluble carbohydrates increased significantly in algal culture. Morphological and ultrastructural changes in M. aeruginosa cells, including breakage of the cell surface, secretion of mucilage, and intracellular disorganization of thylakoids, were observed. HPLC-MS analysis showed that the extracellular substances of Aeromonas sp. strain FM were a mixture of free amino acids, tripeptides, and clavulanate. Among these, the algae-lysis effects of lysine and clavulanate were confirmed.
authors.affiliation: Shandong Provincial Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Jinan, China.
authors.forename: Yu-Mei
authors.initials: YM
authors.lastname: Liu
authors.forename: Ming-Jun
authors.initials: MJ
authors.lastname: Chen
authors.forename: Meng-Hui
authors.initials: MH
authors.lastname: Wang
authors.forename: Rui-Bao
authors.initials: RB
authors.lastname: Jia
authors.forename: Li
authors.initials: L
authors.lastname: Li
mesh_terms: D000333:Aeromonas / Q000737:chemistry / Q000378:metabolism*; D000596:Amino Acids / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D001685:Biological Factors / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D019818:Clavulanic Acid / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D015536:Down-Regulation / Q000187:drug effects; D005110:Extracellular Space / Q000737:chemistry* / Q000378:metabolism; D046931:Microcystis / Q000187:drug effects / Q000254:growth & development*
chemical_list: D000596:Amino Acids; D001685:Biological Factors; D019818:Clavulanic Acid