title: Detection of West Nile virus lineage 2 in Culex mosquitoes, Greece, 2012.
abstract: To gain insight into the strain(s) causing human cases of West Nile virus (WNV) infection in Greece in 2012, mosquitoes were collected and tested for probable WNV infection. WNV lineage 2 sequences were obtained from two of 14 Culex spp. pools collected in Xanthi Prefecture, and especially in the municipality with the highest incidence in Greece. As in the 2 previous years, the strain contains the H249P substitution in the NS3 protein. It seems that this specific strain is fully established in Greece and causes large-scale outbreaks. Thus, prevention and control measures have to be taken, while enhanced surveillance is needed.
authors.affiliation: 1 A' Department of Microbiology, Medical School, Aristotle University of Thessaloniki , Greece .
authors.forename: Anna
authors.initials: A
authors.lastname: Papa
authors.forename: Elpida
authors.initials: E
authors.lastname: Papadopoulou
authors.forename: Elpida
authors.initials: E
authors.lastname: Gavana
authors.forename: Stella
authors.initials: S
authors.lastname: Kalaitzopoulou
authors.forename: Spyros
authors.initials: S
authors.lastname: Mourelatos
mesh_terms: D019943:Amino Acid Substitution; D000818:Animals; D003465:Culex / Q000821:virology*; D004196:Disease Outbreaks; D006115:Greece / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007303:Insect Vectors / Q000821:virology*; D020365:RNA Helicases / Q000235:genetics; D017422:Sequence Analysis, DNA; D012697:Serine Endopeptidases / Q000235:genetics; D017361:Viral Nonstructural Proteins / Q000235:genetics*; D014901:West Nile Fever / Q000453:epidemiology / Q000821:virology*; D014902:West Nile virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D043583:Nucleoside-Triphosphatase; D053487:DEAD-box RNA Helicases; D000085242:Viral Proteases
chemical_list: D020365:RNA Helicases; D012697:Serine Endopeptidases; D017361:Viral Nonstructural Proteins; C060028:NS3 protein, flavivirus; D043583:Nucleoside-Triphosphatase; D053487:DEAD-box RNA Helicases; D000085242:Viral Proteases