title: Cell therapy for lung diseases. Report from an NIH-NHLBI workshop, November 13-14, 2012.
abstract: The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health convened the Cell Therapy for Lung Disease Working Group on November 13-14, 2012, to review and formulate recommendations for future research directions. The workshop brought together investigators studying basic mechanisms and the roles of cell therapy in preclinical models of lung injury and pulmonary vascular disease, with clinical trial experts in cell therapy for cardiovascular diseases and experts from the NHLBI Production Assistance for Cell Therapy program. The purpose of the workshop was to discuss the current status of basic investigations in lung cell therapy, to identify some of the scientific gaps in current knowledge regarding the potential roles and mechanisms of cell therapy in the treatment of lung diseases, and to develop recommendations to the NHLBI and the research community on scientific priorities and practical steps that would lead to first-in-human trials of lung cell therapy.
authors.affiliation: Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Matthay
authors.forename: Piero
authors.initials: P
authors.lastname: Anversa
authors.forename: Jahar
authors.initials: J
authors.lastname: Bhattacharya
authors.forename: Bruce K
authors.initials: BK
authors.lastname: Burnett
authors.forename: Harold A
authors.initials: HA
authors.lastname: Chapman
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Hare
authors.forename: Derek J
authors.initials: DJ
authors.lastname: Hei
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Hoffman
authors.forename: Stella
authors.initials: S
authors.lastname: Kourembanas
authors.forename: David H
authors.initials: DH
authors.lastname: McKenna
authors.forename: Luis A
authors.initials: LA
authors.lastname: Ortiz
authors.forename: Harald C
authors.initials: HC
authors.lastname: Ott
authors.forename: William
authors.initials: W
authors.lastname: Tente
authors.forename: Bernard
authors.initials: B
authors.lastname: Thébaud
authors.forename: Bruce C
authors.initials: BC
authors.lastname: Trapnell
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Weiss
authors.forename: Jason X-J
authors.initials: JX
authors.lastname: Yuan
authors.forename: Carol J
authors.initials: CJ
authors.lastname: Blaisdell
mesh_terms: D035843:Biomedical Research / Q000379:methods*; D064987:Cell- and Tissue-Based Therapy / Q000379:methods*; D006801:Humans; D008171:Lung Diseases / Q000628:therapy*; D054555:National Heart, Lung, and Blood Institute (U.S.); D014481:United States