title: NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes.
authors.affiliation: Department of Radiation Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Murphy
authors.forename: R
authors.initials: R
authors.lastname: Bejar
authors.forename: K
authors.initials: K
authors.lastname: Stevenson
authors.forename: D
authors.initials: D
authors.lastname: Neuberg
authors.forename: Y
authors.initials: Y
authors.lastname: Shi
authors.forename: C
authors.initials: C
authors.lastname: Cubrich
authors.forename: K
authors.initials: K
authors.lastname: Richardson
authors.forename: P
authors.initials: P
authors.lastname: Eastlake
authors.forename: G
authors.initials: G
authors.lastname: Garcia-Manero
authors.forename: H
authors.initials: H
authors.lastname: Kantarjian
authors.forename: B L
authors.initials: BL
authors.lastname: Ebert
authors.forename: G
authors.initials: G
authors.lastname: Mike Makrigiorgos
mesh_terms: D000483:Alleles; D004252:DNA Mutational Analysis; D017931:DNA Primers / Q000737:chemistry / Q000235:genetics; D020558:GTP Phosphohydrolases / Q000235:genetics*; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics*; D009154:Mutation / Q000235:genetics*; D009190:Myelodysplastic Syndromes / Q000235:genetics* / Q000401:mortality; D016133:Polymerase Chain Reaction; D011379:Prognosis; D012307:Risk Factors; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D015996:Survival Rate
chemical_list: D017931:DNA Primers; D008565:Membrane Proteins; D020558:GTP Phosphohydrolases; C579846:NRAS protein, human