title: High TPMT activity as a risk factor for severe myelosuppression during thiopurine therapy.
authors.forename: M L
authors.initials: ML
authors.lastname: Seinen
authors.forename: A A
authors.initials: AA
authors.lastname: van Bodegraven
authors.forename: A B P
authors.initials: AB
authors.lastname: van Kuilenburg
authors.forename: N K H
authors.initials: NK
authors.lastname: de Boer
mesh_terms: D003093:Colitis, Ulcerative / Q000188:drug therapy / Q000201:enzymology*; D016572:Cyclosporine / Q000008:administration & dosage / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects; D007275:Injections, Intravenous; D008297:Male; D008780:Methyltransferases / Q000097:blood*; D010198:Pancytopenia / Q000201:enzymology / Q000209:etiology*; D012307:Risk Factors
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D008780:Methyltransferases; C022745:thiopurine methyltransferase