title: Excellent results and minimal complications of total hip arthroplasty in sickle cell hemoglobinopathy at mid-term follow-up using cementless prosthetic components.
abstract: The purpose of this study was to compare the outcomes of cementless primary total hip arthroplasty (THA) in sickle cell patients compared to the remaining cohort of osteonecrosis patients who did not have this disease. Thirty-two sickle cell patients (42 hips) who had a mean age of 37 years and mean follow-up of 7.5 years (range, 5-11 years) were compared to 87 non-sickle cell osteonecrosis patients (102 hips) who had mean age of 43 years and mean follow-up of 7 years (range, 3-10.5 years). Outcomes evaluated included implant survivorship, Harris hip scores, complication rates, radiographic outcomes, and Short Form-(SF-36) health questionnaire. There were no significant differences in aseptic implant survivorship (95 vs. 97%), Harris hip scores (87 vs. 88 points), SF-36 score, or radiographic findings between the two patient cohorts. In light of these findings, we believe that the outcomes of THA improved in sickle cell patients with optimized medical management and the use of cementless prosthetic devices.
authors.affiliation: Rubin Institute for Advanced Orthopedics, Center for Joint Preservation and Replacement, Sinai Hospital of Baltimore, Baltimore, Maryland.
authors.forename: Kimona
authors.initials: K
authors.lastname: Issa
authors.forename: Qais
authors.initials: Q
authors.lastname: Naziri
authors.forename: Aditya V
authors.initials: AV
authors.lastname: Maheshwari
authors.forename: Vijay J
authors.initials: VJ
authors.lastname: Rasquinha
authors.forename: Ronald E
authors.initials: RE
authors.lastname: Delanois
authors.forename: Michael A
authors.initials: MA
authors.lastname: Mont
mesh_terms: D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D008875:Middle Aged; D010020:Osteonecrosis / Q000209:etiology / Q000601:surgery*; D055815:Young Adult
keywords: Harris hip scores; clinical outcomes; implant survivorship; sickle cell hemoglobinopathy; total hip arthroplasty