title: Purple urine bag syndrome: A case report and review of literature.
abstract: Purple urine bag syndrome (PUBS) is an infrequent condition, seen mostly in elderly female patients, characterized by an intense purple discoloration of contents of urine bag following long-term indwelling urinary catheterization. The purple discoloration is most often due to the presence of indigo and indirubin pigments which are metabolites of tryptophan. Urinary bacteria with indoxyl sulphatase activity metabolize indoxyl sulphate to produce indigo and indirubin, particularly in alkaline urine. We report an elderly woman with a urinary tract infection and constipation who presented with PUBS. The purple urine disappeared after antibiotic therapy and change of the urine bag. To the best of our knowledge, this is the first case of PUBS reported from this region.
authors.affiliation: Department of Medicine, Section of Nephrology, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: S
authors.initials: S
authors.lastname: Yaqub
authors.forename: S
authors.initials: S
authors.lastname: Mohkum
authors.forename: K N
authors.initials: KN
authors.lastname: Mukhtar
keywords: Purple urine bag syndrome; tryptophan; urinary catheters