title: Combined extradural subtemporal and anterior transpetrosal approach to tumors located in the interpeduncular fossa and the upper clivus.
abstract: BACKGROUND
  Central skull base lesions in the interpeduncular fossa and the upper clival regions can be challenging to access because of their location anterior to the brainstem. We have modified the anterior transpetrosal approach by combination with the extradural subtemporal route to increase the surgical corridor.
  
  
  METHODS
  Thirty-seven patients underwent surgical treatment via the anterior transpetrosal approach from 2002 to 2012. The combined surgical approach was primarily applied when the tumors arose from the upper clival portion and extended to the interpeduncular fossa. The combined approach was used in seven of these patients, comprising four patients with petroclival meningiomas, one patient with sphenoclival meningiomas, one patient with trigeminal schwannoma, and one patient with an epidermoid cyst extending from the interpeduncular fossa to the prepontine cistern.
  
  
  RESULTS
  The combined approach permitted excellent visualization of the interpeduncular fossa in addition to the upper clivus and the lateral aspect of the brain stem. Mobilization of the temporal lobe by the entire epidural dissection of the lateral wall of the cavernous sinus facilitates access via the subtemporal route. The transient symptom of the temporal lobe in the dominant site may be the only drawback for this combined approach, although it may disappear immediately after the surgery.
  
  
  CONCLUSIONS
  The present approach combines Dolenc's approach and Kawase's approach, providing a wide exposure to lesions of the interpeduncular fossa and the clivus.
authors.affiliation: Department of Neurosurgery, Graduate School, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8519, Japan. aoyagi@kameda.jp
authors.forename: Masaru
authors.initials: M
authors.lastname: Aoyagi
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Kawano
authors.forename: Masashi
authors.initials: M
authors.lastname: Tamaki
authors.forename: Kaoru
authors.initials: K
authors.lastname: Tamura
authors.forename: Kikuo
authors.initials: K
authors.lastname: Ohno
mesh_terms: D000328:Adult; D000368:Aged; D002426:Cavernous Sinus / Q000473:pathology / Q000601:surgery*; D003388:Cranial Fossa, Posterior / Q000473:pathology / Q000601:surgery*; D003399:Craniotomy / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008579:Meningioma / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods; D019292:Skull Base Neoplasms / Q000473:pathology / Q000601:surgery*; D013701:Temporal Bone / Q000601:surgery; D013702:Temporal Lobe / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult