title: [Research progress of transgenic Drosophila model of Alzheimer disease].
abstract: Alzheimer disease (AD) is a common neurodegenerative disease. Drosophila has been regard as one of the ideal models for Alzheimer because of its unique advantage on genetic manipulation. AD transgenic drosophila models not only help to elucidate the pathogenesis of Alzheimer disease, but also provide potential screening models for drugs to treat the disease. In this review, we summarize the recent research progress using AD transgenic drosophila.
authors.affiliation: Research Center of Life and Environment Science, Harbin University of Commerce, Harbin 150076, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Tan
authors.forename: Yu-Bin
authors.initials: YB
authors.lastname: Ji
authors.forename: Jian
authors.initials: J
authors.lastname: Zhao
mesh_terms: D000544:Alzheimer Disease / Q000209:etiology / Q000235:genetics* / Q000378:metabolism; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D000818:Animals; D030801:Animals, Genetically Modified / Q000235:genetics; D004195:Disease Models, Animal; D004330:Drosophila / Q000235:genetics*; D004353:Drug Evaluation, Preclinical; D018014:Gene Transfer Techniques; D006801:Humans; D010766:Phosphorylation; D016875:tau Proteins / Q000378:metabolism*
chemical_list: D016229:Amyloid beta-Peptides; D016875:tau Proteins