title: Diameters of retinal blood vessels in a healthy cohort as measured by spectral domain optical coherence tomography.
abstract: OBJECTIVE
  To describe a method for measuring the diameters of large retinal blood vessels by means of spectral domain optical coherence tomography.
  
  
  METHODS
  Prospective cohort study of 29 healthy subjects (58 eyes) who underwent a spectral domain optical coherence tomography examination. Two cubes of horizontal scans were placed at the superior and inferior borders of the disk to include the large temporal retinal vessels. Vessels diameters were measured, and an artery-to-vein ratio was calculated at 10 measurement points (480-1440 μm superiorly and inferiorly from the optic disk border).
  
  
  RESULTS
  The mean age of the study subjects was 41.45 ± 15.53 years. Patients had no ocular or systemic pathologies. The mean diameter of the retinal artery was 135.73 ± 15.64 μm and of the vein 151.32 ± 15.22 μm at the measurement point of 480 μm, with a gradual decrease to 123.01 ± 13.43 μm and 137.69 ± 13.84 μm, respectively, at 1440 μm. The artery-to-vein ratio was ≈ 0.9 at all points of measurement.
  
  
  CONCLUSIONS
  This is a new noninvasive method for retinal blood vessels diameter measurement using the spectral domain optical coherence tomography imaging modality. This method may aid in evaluation of retinal and systemic vascular diseases.
authors.affiliation: Department of Ophthalmology, Tel Aviv Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Dafna
authors.initials: D
authors.lastname: Goldenberg
authors.forename: Jonathan
authors.initials: J
authors.lastname: Shahar
authors.forename: Anat
authors.initials: A
authors.lastname: Loewenstein
authors.forename: Michaella
authors.initials: M
authors.lastname: Goldstein
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D009929:Organ Size; D011446:Prospective Studies; D012161:Retinal Artery / Q000033:anatomy & histology*; D012169:Retinal Vein / Q000033:anatomy & histology*; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity / Q000502:physiology