title: Short-term functional outcomes and complications associated with transperineal template prostate mapping biopsy.
abstract: OBJECTIVE
  To assess the complications and erectile and urinary functional outcomes of transperineal template mapping biopsy (TTMB) of the prostate.
  
  
  METHODS
  We retrospectively reviewed the records of 84 patients undergoing TTMB at our institution and recorded complications and functional outcomes. Erectile and urinary functions were measured at baseline, 2 weeks, and 6 ± 2 weeks after TTMB using the International Index of Erectile Function short version (IIEF-5) and International Prostate Symptom Score questionnaires. Erectile and urinary function parameters were compared between baseline and 2 and 6 weeks after TTMB in a paired fashion. A subanalysis of erectile function was performed in preoperatively potent men (IIEF-5 >17).
  
  
  RESULTS
  Sixteen patients (19%) experienced complications. The most common events were transient urinary retention (6%), prostatitis (4%) and local events, including perineal hematoma, bruising, or perineal pain (5%). One patient with hematuria required intervention. IIEF-5 scores at baseline, 2 weeks, and 6 weeks were 20 (interquartile range [IQR], 16-23), 18 (IQR, 12-22), and 18 (IQR, 12-22), respectively (P = .096 and P = .034). Among preoperatively potent men, IIEF-5 scores at baseline, 2 weeks, and 6 weeks were 22 (IQR, 20-24), 21 (IQR, 18-24), and 22 (IQR, 18-24), respectively (P = .011 and P = .018). International Prostate Symptom Scores were 6 (IQR, 3.5-11) at baseline, rose to 10 (IQR, 4.8-15) at 2 weeks (P = .012), and returned to 7 (IQR, 3.5-13) at 6 weeks (P = .628).
  
  
  CONCLUSIONS
  TTMB has a favorable morbidity profile, with mostly mild and transient complications. Urinary retention occurred in 6%, and only 1 patient required intervention with bladder irrigation. Despite a statistically significant decline in erectile function from baseline, the median change in IIEF-5 score was 1 point. Urinary symptoms worsened initially but returned to baseline within 6 weeks.
authors.affiliation: Department of Surgery, Duke University Medical Center, Durham, NC, USA. matvey.tsivian@duke.edu
authors.forename: Matvey
authors.initials: M
authors.lastname: Tsivian
authors.forename: Michael R
authors.initials: MR
authors.lastname: Abern
authors.forename: Peter
authors.initials: P
authors.lastname: Qi
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Polascik
mesh_terms: D000368:Aged; D001707:Biopsy, Needle / Q000009:adverse effects*; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010410:Penile Erection; D010502:Perineum; D011467:Prostate / Q000473:pathology*; D011472:Prostatitis / Q000209:etiology; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D013997:Time Factors; D016055:Urinary Retention / Q000209:etiology