title: Ehrlichia canis infection in a dog with no history of travel outside the United Kingdom.
abstract: A two-year-old female neutered Tibetan terrier was referred following a one-month history of lethargy, inappetence and pancytopenia, which had been poorly responsive to immunosuppressive and fluoroquinolone treatment. The dog was diagnosed with pure red cell aplasia and was found to be positive for Ehrlichia canis by both antibody titre measurement and polymerase chain reaction. The dog lived in London and had not travelled outside the UK. The dog was treated with doxycycline, prednisolone and ciclosporin, but died as a result of gastrointestinal tract haemorrhage. To the authors' knowledge, this represents the first reported case of Ehrlichia canis in a dog in the UK with no previous travel history.
authors.affiliation: Highcroft Veterinary Referrals, 615 Wells Road, Whitchurch, Bristol, BS14 9BE, UK.
authors.forename: H E
authors.initials: HE
authors.lastname: Wilson
authors.forename: A R
authors.initials: AR
authors.lastname: Mugford
authors.forename: K R
authors.initials: KR
authors.lastname: Humm
authors.forename: L M
authors.initials: LM
authors.lastname: Kellett-Gregory
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004283:Dog Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D004285:Dogs; D041061:Ehrlichia canis; D016873:Ehrlichiosis / Q000453:epidemiology / Q000209:etiology / Q000662:veterinary*; D017809:Fatal Outcome; D005260:Female; D016133:Polymerase Chain Reaction / Q000662:veterinary; D014195:Travel; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents