title: Long-term deterioration of bone-conduction hearing level in patients with labyrinthine fistula.
abstract: OBJECTIVE
  Although many reports describe the short-term hearing outcomes of surgically managed labyrinthine fistulae, the long-term results remain unknown. We reviewed the long-term postoperative hearing outcomes of 14 ears of patients with cholesteatoma and labyrinthine fistulae.
  
  
  METHODS
  Between 1996 and 2010, 84 patients with cholesteatoma and labyrinthine fistula underwent tympanoplasty at Hyogo College of Medicine Hospital. Fistulae were located in the lateral semicircular canal in all patients and in the superior semicircular canal in one. Fourteen patients were followed up for more than 5 years.
  
  
  RESULTS
  The postoperative air-bone gap was ≤10dB in one patient, between 11 and 20dB in seven, between 21 and 30dB in four, and ≥31dB in two. Mean bone-conduction hearing levels on the operated side had deteriorated by 3, -1 and -2dB at 1, 2 and 4kHz, respectively at 1 year postoperatively, and by 8, 6 and 2dB at 1, 2 and 4kHz, at 5 years postoperatively. Bone-conduction hearing levels at 1 and 2kHz were significantly deteriorated at 5 years postoperatively, compared with baseline and 1 year (P<0.05).
authors.affiliation: Department of Otolaryngology, Hyogo College of Medicine, Nishinomiya-City, Hyogo, Japan. Electronic address: hkatsura@hyo-med.ac.jp.
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Katsura
authors.affiliation: Department of Otolaryngology, Hyogo College of Medicine, Nishinomiya-City, Hyogo, Japan.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Mishiro
authors.affiliation: Department of Otolaryngology, Hyogo College of Medicine, Nishinomiya-City, Hyogo, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Adachi
authors.affiliation: Department of Otolaryngology, Hyogo College of Medicine, Nishinomiya-City, Hyogo, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Ogino
authors.affiliation: Department of Biostatistics, Hyogo College of Medicine, Nishinomiya-City, Hyogo, Japan.
authors.forename: Tadashi
authors.initials: T
authors.lastname: Daimon
authors.affiliation: Department of Otolaryngology, Hyogo College of Medicine, Nishinomiya-City, Hyogo, Japan.
authors.forename: Masafumi
authors.initials: M
authors.lastname: Sakagami
mesh_terms: D000368:Aged; D001844:Bone Conduction; D018424:Cholesteatoma, Middle Ear / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D005402:Fistula / Q000601:surgery*; D006314:Hearing Loss, Conductive; D006320:Hearing Tests; D006801:Humans; D007759:Labyrinth Diseases / Q000601:surgery*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012665:Semicircular Canals / Q000601:surgery*; D016896:Treatment Outcome; D014433:Tympanoplasty / Q000379:methods*
keywords: Bone-conduction hearing level; Cholesteatoma; Labyrinthine fistula