title: Emerging tools for synthetic genome design.
abstract: Synthetic biology is an emerging discipline for designing and synthesizing predictable, measurable, controllable, and transformable biological systems. These newly designed biological systems have great potential for the development of cheaper drugs, green fuels, biodegradable plastics, and targeted cancer therapies over the coming years. Fortunately, our ability to quickly and accurately engineer biological systems that behave predictably has been dramatically expanded by significant advances in DNA-sequencing, DNA-synthesis, and DNA-editing technologies. Here, we review emerging technologies and methodologies in the field of building designed biological systems, and we discuss their future perspectives.
authors.affiliation: Intelligent Synthetic Biology Center, Daejeon, 305-701, Korea.
authors.forename: Bo-Rahm
authors.initials: BR
authors.lastname: Lee
authors.forename: Suhyung
authors.initials: S
authors.lastname: Cho
authors.forename: Yoseb
authors.initials: Y
authors.lastname: Song
authors.forename: Sun Chang
authors.initials: SC
authors.lastname: Kim
authors.forename: Byung-Kwan
authors.initials: BK
authors.lastname: Cho
mesh_terms: D004247:DNA / Q000737:chemistry / Q000378:metabolism; D016678:Genome; D023281:Genomics / Q000379:methods*; D006801:Humans; D017422:Sequence Analysis, DNA; D058615:Synthetic Biology / Q000379:methods* / Q000639:trends
chemical_list: D004247:DNA