title: Prognostic analysis of endometrioid epithelial ovarian cancer with or without endometriosis: a 12-year cohort study of Chinese patients.
abstract: OBJECTIVE
  Clinicopathological characteristics and possible prognostic factors among women with endometrioid epithelial ovarian cancer (EEOC) with or without concurrent endometriosis were investigated.
  
  
  METHODS
  A search of medical charts at Peking Union Medical College Hospital from 2000 through 2012 identified patients with EEOC with or without endometriosis.
  
  
  RESULTS
  Of 188 patients with EEOC, concurrent endometriosis was identified in 32 (17.0%). Patients with concurrent endometriosis were approximately 5 years younger, more likely to be premenopausal, more likely to have an early stage of EEOC, and less likely to have high-grade tumors compared to those without endometriosis. The univariate analysis showed that concurrent endometriosis was a significant prognostic factor for disease-free survival, but this association did not remain in the multivariate analysis.
  
  
  CONCLUSIONS
  Women with EEOC and concurrent endometriosis showed distinct characteristics and had longer disease-free survival when compared to those without endometriosis.
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, PR China.
authors.forename: Shu
authors.initials: S
authors.lastname: Wang
authors.forename: Lin
authors.initials: L
authors.lastname: Qiu
authors.forename: Jing He
authors.initials: JH
authors.lastname: Lang
authors.forename: Keng
authors.initials: K
authors.lastname: Shen
authors.forename: Hui Fang
authors.initials: HF
authors.lastname: Huang
authors.forename: Ling Ya
authors.initials: LY
authors.lastname: Pan
authors.forename: Ming
authors.initials: M
authors.lastname: Wu
authors.forename: Jia Xin
authors.initials: JX
authors.lastname: Yang
authors.forename: Li Na
authors.initials: LN
authors.lastname: Guo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000077216:Carcinoma, Ovarian Epithelial; D015331:Cohort Studies; D018572:Disease-Free Survival; D004715:Endometriosis / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000401:mortality* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000401:mortality* / Q000473:pathology; D011379:Prognosis; D016016:Proportional Hazards Models
keywords: endometrioid epithelial ovarian cancer; endometriosis prognostic factor; survival