title: Daily short message service surveys to measure sexual behavior and pre-exposure prophylaxis use among Kenyan men and women.
abstract: Pre-exposure prophylaxis (PrEP) is a novel HIV prevention strategy which requires high adherence. We tested the use of daily short message service (i.e., SMS/text message) surveys to measure sexual behavior and PrEP adherence in Kenya. Ninety-six HIV-uninfected adult individuals, taking daily oral PrEP in a clinical trial, received daily SMS surveys for 60 days. Most participants (96.9 %) reported taking PrEP on ≥80 % days, but 69.8 % missed at least one dose. Unprotected sex was reported on 4.9 % of days; however, 47.9 % of participants reported unprotected sex at least once. Unprotected sex was not correlated with PrEP use (OR = 0.95). Participants reporting more sex were less likely to report PrEP non-adherence and those reporting no sex were most likely to report missing a PrEP dose (adjusted OR = 1.87). PrEP adherence was high, missed doses were correlated with sexual abstinence, and unprotected sex was not associated with decreased PrEP adherence.
authors.affiliation: Department of Epidemiology, University of Washington, Seattle, WA, USA, kgcurran@uw.edu.
authors.forename: Kathryn
authors.initials: K
authors.lastname: Curran
authors.forename: Nelly R
authors.initials: NR
authors.lastname: Mugo
authors.forename: Ann
authors.initials: A
authors.lastname: Kurth
authors.forename: Kenneth
authors.initials: K
authors.lastname: Ngure
authors.forename: Renee
authors.initials: R
authors.lastname: Heffron
authors.forename: Deborah
authors.initials: D
authors.lastname: Donnell
authors.forename: Connie
authors.initials: C
authors.lastname: Celum
authors.forename: Jared M
authors.initials: JM
authors.lastname: Baeten
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D005260:Female; D015658:HIV Infections / Q000191:economics / Q000453:epidemiology / Q000517:prevention & control*; D006801:Humans; D007630:Kenya / Q000453:epidemiology; D008297:Male; D010349:Patient Compliance; D010865:Pilot Projects; D057566:Self Report; D012725:Sexual Behavior / Q000706:statistics & numerical data*; D060145:Text Messaging / Q000191:economics / Q000706:statistics & numerical data; D016903:Drug Monitoring
chemical_list: D019380:Anti-HIV Agents