title: [Changes of oxidative homeostasis in acute experimental cholecystitis].
abstract: Variations of the indices of endogenous intoxication, lipid peroxidation, oxidative modification of proteins, and antioxidant system operation have been studied in animals with acute experimental cholecystitis. The possibility and effectiveness of using succinate-containing drugs reamberin and mexidol for the correction of these impairments has been assessed. In the present study, reamberin effectively reduced the intensity of lipid peroxidation and protein modification in experimental animals.
authors.forename: S V
authors.initials: SV
authors.lastname: Iakubovskiĭ
authors.forename: S I
authors.initials: SI
authors.lastname: Leonovich
authors.forename: G G
authors.initials: GG
authors.lastname: Kondratenko
authors.forename: I I
authors.initials: II
authors.lastname: Popova
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001798:Blood Proteins / Q000378:metabolism; D002374:Catalase / Q000097:blood; D041881:Cholecystitis, Acute / Q000097:blood* / Q000188:drug therapy* / Q000503:physiopathology; D004195:Disease Models, Animal; D005260:Female; D006168:Guinea Pigs; D007273:Injections, Intramuscular; D007274:Injections, Intraperitoneal; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008536:Meglumine / Q000031:analogs & derivatives* / Q000494:pharmacology; D010084:Oxidation-Reduction / Q000187:drug effects; D018384:Oxidative Stress / Q000187:drug effects; D010847:Picolines / Q000494:pharmacology*; D013386:Succinates / Q000494:pharmacology*; D013482:Superoxide Dismutase / Q000097:blood
chemical_list: D000975:Antioxidants; D001798:Blood Proteins; D010847:Picolines; C549374:Reamberin; D013386:Succinates; C070020:emoxypine succinate; D008315:Malondialdehyde; D008536:Meglumine; D002374:Catalase; D013482:Superoxide Dismutase