title: [Pharmaceutical study on multi-component traditional Chinese medicines].
abstract: Due to the limitation of science and technology in ancient times, traditional Chinese medicines (TCMs) could have prepared only in traditional dosage forms, such as pills, powders, ointments and pellets. Though studies on multi-component TCMs have become one of major development orientations of TCM, the druggability of their preparations has always been neglected. On the basis of two key difficulties--the integration of studies on multi-component TCMs and TCM theory as well as the evaluation on their druggability, the essay proposes methods and technologies that can be adopted in studies on multi-component TCM preparations, including the characteristic physicochemical property of multi-component TCMs and its correlation with forming process, the release-modified micro pill preparation technology based on prescription-symptom-dosage, and the evaluation technology on release of release-modified micro pill components based on mathematical set model.
authors.affiliation: Engineering Research Center of Modern Traditional Chinese Medicine Preparation Technology of Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. fyi@vip.sina.com
authors.forename: Yi
authors.initials: Y
authors.lastname: Feng
authors.forename: Xiao
authors.initials: X
authors.lastname: Lin
authors.forename: Lan
authors.initials: L
authors.lastname: Shen
authors.forename: Yan-Long
authors.initials: YL
authors.lastname: Hong
mesh_terms: D055598:Chemical Phenomena; D004339:Drug Compounding; D054796:Drug Dosage Calculations; D008516:Medicine, Chinese Traditional / Q000379:methods*; D008962:Models, Theoretical