title: Multiple players in mouse B cell memory.
abstract: B cell memory has long been considered the attribute of the sole IgG-positive B cell subset. Since a few years, and due to new B-cell subset identification procedures, increasing heterogeneity has been identified among the memory B cell pool. IgM-positive cells and germinal center-independent subsets are recent additions to the field. This review describes the diversity of memory B cells, as well as controversial issues on their relative contribution to the recall response. The impact of a protracted germinal center response to the specific mobilization of IgM memory B cells is proposed.
authors.affiliation: INSERM U783 Développement du système immunitaire, Université Paris Descartes, Faculté de Médecine, Site Broussais, 96 rue Didot, Paris, France. jean-claude.weill@inserm.fr
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Weill
authors.forename: Simon
authors.initials: S
authors.lastname: Le Gallou
authors.forename: Yi
authors.initials: Y
authors.lastname: Hao
authors.forename: Claude-Agnès
authors.initials: CA
authors.lastname: Reynaud
mesh_terms: D000818:Animals; D000941:Antigens / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology*; D018858:Germinal Center / Q000276:immunology; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D007156:Immunologic Memory; D051379:Mice
chemical_list: D000941:Antigens; D007075:Immunoglobulin M