title: Nonarteritic anterior ischemic optic neuropathy and obstructive sleep apnea.
abstract: BACKGROUND
  To evaluate the obstructive sleep apnea syndrome (OSAS) in patients with nonarteritic anterior ischemic optic neuropathy (NAION).
  
  
  METHODS
  We recruited 27 patients with NAION and 27 age-matched and sex-matched controls who also were similar for systemic risk factors such as diabetes mellitus, hypertension, and hypercholesterolemia. All patients and controls underwent overnight polysomnography for the diagnosis of OSAS and calculation of apnea-hypopnea index (AHI).
  
  
  RESULTS
  Patients and controls were statistically similar in terms of age, sex, gender, smoking, systemic risk factors, neck circumference, and body mass index. The subjects with AHI ≥ 20 were accepted as OSAS. Fifteen of 27 patients (55.6%) with NAION and 6 of 27 controls (22.2%) had OSAS (P < 0.05).
  
  
  CONCLUSIONS
  The prevalence of OSAS was higher in patients with NAION, and the difference between patient and control groups was statistically significant (P < 0.05). This result supports prior series suggesting the association between NAION and OSAS.
authors.affiliation: Jules Stein Eye Institute, Neuro-Ophthalmology Division, University of California, Los Angeles, Los Angeles, California, USA. gorkemgencebilgin@gmail.com
authors.forename: Gorkem
authors.initials: G
authors.lastname: Bilgin
authors.forename: Yaran
authors.initials: Y
authors.lastname: Koban
authors.forename: Anthony C
authors.initials: AC
authors.lastname: Arnold
mesh_terms: D000368:Aged; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018917:Optic Neuropathy, Ischemic / Q000150:complications* / Q000503:physiopathology; D017286:Polysomnography; D011446:Prospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology