title: Dextran based sensitive theranostic nanoparticles for near-infrared imaging and photothermal therapy in vitro.
abstract: Indocyanine green (ICG) nanoparticles were developed via electrostatic interactions of ICG and dextran based block copolymers (PEG-dextran(-SS-NH2)) as near-infrared (NIR) theranostic nanoparticles. The nanoparticles could be activated from "OFF" to "ON" of NIR fluorescence in an intracellular environment and used for NIR imaging and photothermal therapy.
authors.affiliation: CAS Key Laboratory of Health Informatics, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
authors.forename: Peng
authors.initials: P
authors.lastname: Liu
authors.forename: Caixia
authors.initials: C
authors.lastname: Yue
authors.forename: Bihua
authors.initials: B
authors.lastname: Shi
authors.forename: Guanhui
authors.initials: G
authors.lastname: Gao
authors.forename: Mingxing
authors.initials: M
authors.lastname: Li
authors.forename: Bi
authors.initials: B
authors.lastname: Wang
authors.forename: Yifan
authors.initials: Y
authors.lastname: Ma
authors.forename: Lintao
authors.initials: L
authors.lastname: Cai
mesh_terms: D002470:Cell Survival / Q000187:drug effects / Q000528:radiation effects; D003911:Dextrans / Q000008:administration & dosage; D003952:Diagnostic Imaging / Q000379:methods; D005453:Fluorescence; D006801:Humans; D006979:Hyperthermia, Induced; D007208:Indocyanine Green / Q000008:administration & dosage; D007259:Infrared Rays; D007834:Lasers; D061986:MCF-7 Cells; D053758:Nanoparticles / Q000008:administration & dosage; D010789:Phototherapy
chemical_list: D003911:Dextrans; D007208:Indocyanine Green