title: Disrupting the old order of imaging.
abstract: OBJECTIVE
  The purpose of this article is to expand on the economic concepts of creative destruction and disruptive innovation to imagine scenarios in which diagnostic imaging modalities and certain imaging paradigms can be rendered obsolete.
  
  
  CONCLUSIONS
  Potential disrupters of imaging are novel drugs, clinical trials, accurate biomarkers, and government regulations. A taxonomic schema can be used to better predict the decline of certain imaging modalities.
authors.affiliation: Department of Radiology, MRI Learning Center, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA. saurabh.jha@uphs.upenn.edu
authors.forename: Saurabh
authors.initials: S
authors.lastname: Jha
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Lexa
mesh_terms: D015415:Biomarkers; D002986:Clinical Trials as Topic; D003405:Creativity; D003952:Diagnostic Imaging / Q000191:economics* / Q000639:trends*; D004059:Diffusion of Innovation; D033161:Government Regulation; D006801:Humans; D004364:Pharmaceutical Preparations
chemical_list: D015415:Biomarkers; D004364:Pharmaceutical Preparations