title: Evaluation of a calcium phosphate desensitizer using an ultrasonic device.
abstract: This study evaluated the effect of a calcium phosphate desensitizer on the demineralization of bovine dentin by measuring changes in transmitted ultrasonic velocity. Bovine dentin specimens with and without application of desensitizer were immersed in 0.1 M lactic-acid buffer solution (pH 4.75) 10 min twice daily throughout the test period, and stored in artificial saliva solution (pH 7.0) between treatments. The propagation time of longitudinal ultrasonic waves was measured by a pulser-receiver. Data were evaluated using one-way ANOVA followed by Tukey HSD test (α=0.05). The ultrasonic velocity decreased over time in specimens stored in demineralizing solution (3,785-3,462 m/s); however, desensitizer-applied specimens had a significantly higher sonic velocity (3,945-3,990 m/s) than those without application. The calcium phosphate desensitizer appeared to reduce the demineralization of dentin and occluded dentinal tubules.
authors.affiliation: Department of Operative Dentistry, Nihon University School of Dentistry, 1-8-13 Kandasurugadai, Chiyoda-ku, Tokyo 101-8310, Japan.
authors.forename: Hajime
authors.initials: H
authors.lastname: Endo
authors.forename: Ryo
authors.initials: R
authors.lastname: Kawamoto
authors.forename: Fuminori
authors.initials: F
authors.lastname: Takahashi
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Takenaka
authors.forename: Fumi
authors.initials: F
authors.lastname: Yoshida
authors.forename: Kie
authors.initials: K
authors.lastname: Nojiri
authors.forename: Toshiki
authors.initials: T
authors.lastname: Takamizawa
authors.forename: Masashi
authors.initials: M
authors.lastname: Miyazaki
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D002021:Buffers; D002130:Calcium Phosphates / Q000494:pharmacology / Q000627:therapeutic use*; D002417:Cattle; D003738:Dental Cements / Q000494:pharmacology / Q000627:therapeutic use; D003804:Dentin / Q000000981:diagnostic imaging / Q000187:drug effects / Q000648:ultrastructure; D057133:Dentin Desensitizing Agents / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D006863:Hydrogen-Ion Concentration; D019344:Lactic Acid; D008855:Microscopy, Electron, Scanning; D012464:Saliva, Artificial; D018709:Statistics, Nonparametric; D017001:Tooth Demineralization / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014463:Ultrasonography
chemical_list: D002021:Buffers; D002130:Calcium Phosphates; D003738:Dental Cements; D057133:Dentin Desensitizing Agents; D012464:Saliva, Artificial; D019344:Lactic Acid