title: Acute MI in a young hypertensive woman: could it be due to tranexamic acid?
abstract: The case report illustrates an acute myocardial infarction (MI) in a 41-year-old hypertensive woman possibly because of an intake of a combination of tranexamic acid and mefenamic acid for dysmenorrhoea and menorrhagia. There are multiple case reports of MI occurring in the setting of the use of antifibrinolytic agents including tranexamic acid. The present case serves as a warning that, even in patients with an apparently low risk for arterial thrombosis, these drugs may be implicated as a precipitant of MI.
authors.affiliation: Department of Cardiology, Medical College Hospital, Trivandrum, Kerala, India. ninigupta@gmail.com
authors.forename: Prabha Nini
authors.initials: PN
authors.lastname: Gupta
authors.forename: Ullas R
authors.initials: UR
authors.lastname: Mullamalla
authors.forename: P
authors.initials: P
authors.lastname: Sabin
authors.forename: Praveen
authors.initials: P
authors.lastname: Vellappan
mesh_terms: D000328:Adult; D000933:Antifibrinolytic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D009203:Myocardial Infarction / Q000139:chemically induced / Q000150:complications / Q000175:diagnosis*; D014148:Tranexamic Acid / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000933:Antifibrinolytic Agents; D014148:Tranexamic Acid