title: Modeling the spatial distribution of Chagas disease vectors using environmental variables and people´s knowledge.
abstract: BACKGROUND
  Chagas disease is caused by the protozoan Trypanosoma cruzi, which is transmitted to mammal hosts by triatomine insect vectors. The goal of this study was to model the spatial distribution of triatomine species in an endemic area.
  
  
  METHODS
  Vector's locations were obtained with a rural householders' survey. This information was combined with environmental data obtained from remote sensors, land use maps and topographic SRTM data, using the machine learning algorithm Random Forests to model species distribution. We analysed the combination of variables on three scales: 10 km, 5 km and 2.5 km cell size grids.
  
  
  RESULTS
  The best estimation, explaining 46.2% of the triatomines spatial distribution, was obtained for 5 km of spatial resolution. Presence probability distribution increases from central Chile towards the north, tending to cover the central-coastal region and avoiding areas of the Andes range.
  
  
  CONCLUSIONS
  The methodology presented here was useful to model the distribution of triatomines in an endemic area; it is best explained using 5 km of spatial resolution, and their presence increases in the northern part of the study area. This study's methodology can be replicated in other countries with Chagas disease or other vectorial transmitted diseases, and be used to locate high risk areas and to optimize resource allocation, for prevention and control of vectorial diseases.
authors.forename: Jaime
authors.initials: J
authors.lastname: Hernández
authors.forename: Ignacia
authors.initials: I
authors.lastname: Núñez
authors.forename: Antonella
authors.initials: A
authors.lastname: Bacigalupo
authors.forename: Pedro E
authors.initials: PE
authors.lastname: Cattan
mesh_terms: D000818:Animals; D014355:Chagas Disease / Q000175:diagnosis / Q000453:epidemiology*; D002677:Chile / Q000453:epidemiology; D003625:Data Collection / Q000379:methods*; D004199:Disease Vectors; D004777:Environment; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008954:Models, Biological; D012424:Rural Population / Q000639:trends; D014349:Trypanosoma cruzi / Q000302:isolation & purification*