title: Ruthenium-catalyzed aerobic oxidative cyclization of aromatic and heteroaromatic nitriles with alkynes: a new route to isoquinolones.
abstract: The oxidative cyclization of aromatic and heteroaromatic nitriles with alkynes in the presence of a catalytic amount of [{RuCl2(p-cymene)}2], Cu(OAc)2·H2O and KPF6 in acetic acid under air gave isoquinolones in good to excellent yields.
authors.affiliation: Department of Chemistry, Indian Institute of Science Education and Research, Pune 411021, India.
authors.forename: Mallu Chenna
authors.initials: MC
authors.lastname: Reddy
authors.forename: Rajendran
authors.initials: R
authors.lastname: Manikandan
authors.forename: Masilamani
authors.initials: M
authors.lastname: Jeganmohan
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D009570:Nitriles / Q000737:chemistry*; D010084:Oxidation-Reduction; D015363:Quinolones / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D009570:Nitriles; D015363:Quinolones; D003300:Copper; D012428:Ruthenium