title: [Constituents of Dendrobium devonianum and their antioxidant activity].
abstract: OBJECTIVE
  To study the chemical constituents of Dendrobium devonianum and identify the material basis components of its function, and then provide the basis for development and utilization of D. devonianum.
  
  
  METHODS
  The constituents were separated and purified on the chromatography of silica gel, Sephadex LH-20 and RP-18 silica gel, and then their structures were elucidated based on the spectra data. ABTS method was used to evaluate the free radical scavenging activity of the phenolic compounds among them.
  
  
  RESULTS
  Nine compounds were isolated and identified as 2,3,4,9-tetrahydro-1H-pyrido[3,4-b] indole-3-carboxylic acid (1), 2'-deoxythymidine (2), adenosine (3), N-trans-p-coumaroyl tyramine (4), N-trans-p-feruloyl tyramine (5), 3-methoxy-4-hydroxybenzaldehyde (6), 4-hydroxybenzaldehyde (7), 3,4-dihydroxybenzoic acid methyl ester (8), and 4-hydroxy-3,5-dimethoxybenzoic acid (9). Compound 5 showed good antioxidant activity with IC50 1. 61 mmol. L-1, Compound 9 showed weak antioxidant activity with IC50 35.72 mmol. L-1.
  
  
  CONCLUSIONS
  All these compounds were isolated from D. devonianum for the first time. Among them, compounds 5 and 9 had some antioxidant activity.
authors.affiliation: Nurturing Station for the State Key Laboratory of Subtropical Silviculture, Zhejiang Provinical Strategic Alliance for Technical Innovation in Industry of Dendrobium Officinale Zhejiang Agricultural and Forestry University, Lin'an 311300, China. zhangailian@126.com
authors.forename: Ai-Lian
authors.initials: AL
authors.lastname: Zhang
authors.forename: Min
authors.initials: M
authors.lastname: Yu
authors.forename: Hong-Hua
authors.initials: HH
authors.lastname: Xu
authors.forename: Jin-Ping
authors.initials: JP
authors.lastname: Si
mesh_terms: D031667:Dendrobium / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D020128:Inhibitory Concentration 50
chemical_list: D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers