title: Evaluation of the slip length in the slipping friction between background electrolytes and peptides through the modeling of their capillary zone electrophoretic mobilities.
abstract: This work analyzes and discusses several physicochemical peptide chain properties that may generate partial or total BGE slip boundary conditions on the surface of peptides migrating as spherical and aspherical particles in CZE. A definition of the BGE slip length is presented that is able to account the effect of particle curvature through the associated metrical coefficients. This definition allows the distinction between partial and total BGE slip lengths. It is also shown that the BGE slip length must be variable on orthotropic aspherical particles surfaces.
authors.affiliation: Instituto de Desarrollo Tecnológico para la Industria Química (INTEC), UNL, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fe, Argentina.
authors.forename: Julio A
authors.initials: JA
authors.lastname: Deiber
authors.forename: Maria V
authors.initials: MV
authors.lastname: Piaggio
authors.forename: Marta B
authors.initials: MB
authors.lastname: Peirotti
mesh_terms: D003198:Computer Simulation; D004573:Electrolytes / Q000737:chemistry*; D019075:Electrophoresis, Capillary / Q000379:methods*; D017276:Friction; D057446:Hydrodynamics; D057927:Hydrophobic and Hydrophilic Interactions; D008956:Models, Chemical; D010455:Peptides / Q000737:chemistry*
chemical_list: D004573:Electrolytes; D010455:Peptides
keywords: Fluid slip boundary condition; Hydrophobic peptides; Partial and total slip lengths; Peptide effective electrophoretic mobility; Slip friction coefficient