title: A quantitative magnetic resonance study of the hippocampus and the temporal horn of the lateral ventricle in healthy subjects.
abstract: OBJECTIVE
  Hippocampal volume has been measured and used to separate the people who have Alzheimer disease, stress-related psychiatric disorders such as posttraumatic stress disorder, borderline personality disorder, and schizophrenia from normal people. Owing to the long time to measure the volume of the hippocampus and the difficulty to measure temporal horn, we established standard values of the area, width, and height of hippocampus and temporal horn of the lateral ventricle in certain planes in healthy subjects to aid in the clinical diagnosis.
  
  
  METHODS
  We measured the area, height, and width of the hippocampus and the temporal horn of the lateral ventricle and the area of both structures in the planes that are perpendicular to the long axis of the hippocampus on magnetic resonance images in 105 healthy subjects.
  
  
  RESULTS
  Measured data of hippocampus and temporal horn are presented as mean ± SD. The results of measurement of hippocampus and temporal horn are provided separately.
  
  
  CONCLUSIONS
  We obtained the reference range in healthy people, and we found that there is a descending trend in area, width, and height of the hippocampus when the planes were taken from mamillary body to interthalamic adhesion. The difference between the 2 sides shows no significance in terms of areas of hippocampus, P > 0.05. However, width and height of the hippocampus have significant difference between the 2 sides except width measured in the plane passing the interthalamic adhesion, P < 0.01. The effect of sex on the values of measurement cannot be obtained, P < 0.01.
authors.affiliation: Department of Anatomy, Norman Bethune Medical School, Jilin University, Changchun, Jilin, People's Republic of China.
authors.forename: Wenjia
authors.initials: W
authors.lastname: Zhang
authors.forename: Xue
authors.initials: X
authors.lastname: Wang
authors.forename: Zijian
authors.initials: Z
authors.lastname: Zhou
authors.forename: You Qiong
authors.initials: YQ
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006624:Hippocampus / Q000033:anatomy & histology*; D006801:Humans; D020547:Lateral Ventricles / Q000033:anatomy & histology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D013702:Temporal Lobe / Q000033:anatomy & histology*; D055815:Young Adult