title: Characterization of speckle in lung images acquired with a benchtop in-line x-ray phase-contrast system.
abstract: We investigate the manifestation of speckle in propagation-based x-ray phase-contrast imaging of mouse lungs in situ by use of a benchtop imager. The key contributions of the work are the demonstration that lung speckle can be observed by use of a benchtop imaging system employing a polychromatic tube-source and a systematic experimental investigation of how the texture of the speckle pattern depends on the parameters of the imaging system. Our analyses consists of image texture characterization based on the statistical properties of pixel intensity values.
authors.affiliation: Department of Biomedical Engineering, Washington University in St Louis, St Louis, MO 63130, USA.
authors.forename: A B
authors.initials: AB
authors.lastname: Garson
authors.forename: E W
authors.initials: EW
authors.lastname: Izaguirre
authors.forename: S G
authors.initials: SG
authors.lastname: Price
authors.forename: M A
authors.initials: MA
authors.lastname: Anastasio
mesh_terms: D000818:Animals; D003116:Color; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008168:Lung / Q000000981:diagnostic imaging*; D051379:Mice; D014057:Tomography, X-Ray Computed / Q000379:methods*