title: A highly selective turn-on ATP fluorescence sensor based on unmodified cysteamine capped CdS quantum dots.
abstract: Unmodified cysteamine capped nanocrystalline cadmium sulfide quantum dots (Cys-CdS QDs) were demonstrated as a selective turn-on fluorescence sensor for sensing adenosine-5'-triphosphate (ATP) in aqueous solution for the first time. The fluorescence intensity of the Cys-CdS QDs was significantly enhanced in the presence of ATP. In addition, the fluorescence intensity of the Cys-CdS QDs increased when increasing ATP concentrations. On the other hand, other phosphate metabolites and other tested common anions did not significantly alter the fluorescence intensity of the Cys-CdS QDs. In addition, this sensor showed excellent discrimination of pyrophosphate (PPi) from ATP detection. The proposed sensor could efficiently be used for ATP sensing at very low concentration with LOD of 17 μM with the linear working concentration range of 20-80 μM. The feasibility of the proposed sensor for determining ATP in urine samples was also studied, and satisfactory results were obtained.
authors.affiliation: Materials Chemistry Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
authors.forename: Wimonsiri
authors.initials: W
authors.lastname: Tedsana
authors.forename: Thawatchai
authors.initials: T
authors.lastname: Tuntulani
authors.forename: Wittaya
authors.initials: W
authors.lastname: Ngeontae
mesh_terms: D000255:Adenosine Triphosphate / Q000737:chemistry* / Q000652:urine; D019187:Cadmium Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D002623:Chemistry Techniques, Analytical; D003543:Cysteamine / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006801:Humans; D045663:Quantum Dots; D013440:Sulfides / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D019187:Cadmium Compounds; D005456:Fluorescent Dyes; D013440:Sulfides; C034939:cadmium sulfide; D003543:Cysteamine; D000255:Adenosine Triphosphate