title: Comparison of HbA1c levels in obese and non-obese polycystic ovarian patients.
abstract: OBJECTIVE
  To compare obese and non-obese polycystic ovary syndrome (PCOS) patients with respect to lipid profile, hormone profiles, and hemoglobin A1c (HbA1c) values indicating chronic hyperglicemia.
  
  
  METHODS
  Thirty PCOS patients with a body mass index (BMI) > 25 and 35 non-obese PCOS patients with BMI < 25 were compared with regard to basal luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), estradiol (E2), fasting blood sugar (FBS), low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TCOL), triglyceride (TG), and HbA1c values.
  
  
  RESULTS
  HDL value (p = 0.005) was significantly higher in non-obese group while TG (p = 0.001) was higher in the obese group. No significant difference was found between other values.
  
  
  CONCLUSIONS
  Lipid metabolism impairment seems to be more marked in obese PCOS patients. Moreover, it is obvious that insulin resistance is higher in obese group. The absent difference between obese and non-obese groups in terms of HbA1c values suggests that insulin resistance occurring in the obese group may also be important in the non-obese group. In this context, cardiovascular risks may increase in non-obese PCOS patients.
authors.affiliation: Department of Obstetrics and Gynecology, Bilecik Central Hospital, Bilecik, Turkey.
authors.forename: A N
authors.initials: AN
authors.lastname: Unluer
authors.forename: R B
authors.initials: RB
authors.lastname: Findik
authors.forename: N
authors.initials: N
authors.lastname: Sevinc
authors.forename: J
authors.initials: J
authors.lastname: Karakaya
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006801:Humans; D007333:Insulin Resistance; D050356:Lipid Metabolism; D009765:Obesity / Q000097:blood / Q000150:complications*; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000150:complications*; D055815:Young Adult
chemical_list: D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human