title: Transannular reductive rearrangement of α-amino ketones: construction of aza-tricyclic frameworks of several alkaloids.
abstract: Transannular reductive rearrangement of bridged cyclic α-amino ketones led to the aza-tricyclic frameworks azepinoindole, hydrolulolidine, and hydrojulolidine of the typical alkaloids of Stemona, Aspidosperma, and Lycopodium, respectively. This facile approach demonstrates the potential applicability of the Clemmensen-Clemo-Prelog-Leonard reductive rearrangement of tricyclic α-amino ketones for the aza-heterocycle synthesis.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.forename: Yong-Qiang
authors.initials: YQ
authors.lastname: Wang
authors.forename: Xin-Wei
authors.initials: XW
authors.lastname: Wang
authors.forename: Wei-Dong Z
authors.initials: WD
authors.lastname: Li