title: Surface functionalization of gold nanoparticles with red blood cell membranes.
abstract: Gold nanoparticles are enclosed in cellular membranes derived from natural red blood cells (RBCs) by a top-down approach. The gold nanoparticles exhibit a complete membrane surface layer and biological characteristics of the source cells. The combination of inorganic gold nanoparticles with biological membranes is a compelling way to develop biomimetic gold nanostructures for future applications, such as those requiring evasion of the immune system.
authors.affiliation: Department of NanoEngineering and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.
authors.forename: Weiwei
authors.initials: W
authors.lastname: Gao
authors.forename: Che-Ming J
authors.initials: CM
authors.lastname: Hu
authors.forename: Ronnie H
authors.initials: RH
authors.lastname: Fang
authors.forename: Brian T
authors.initials: BT
authors.lastname: Luk
authors.forename: Jing
authors.initials: J
authors.lastname: Su
authors.forename: Liangfang
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000818:Animals; D002460:Cell Line; D004910:Erythrocyte Membrane / Q000378:metabolism*; D006046:Gold / Q000737:chemistry* / Q000378:metabolism*; D008297:Male; D053768:Metal Nanoparticles / Q000737:chemistry*; D051379:Mice; D008958:Models, Molecular; D008968:Molecular Conformation; D010586:Phagocytes; D013499:Surface Properties
chemical_list: D006046:Gold
keywords: biomimetics; gold nanoparticles; nanomedicine; red blood cells; surface functionalization