title: 2-octyl-cyanoacrylate glue for fixation of STSG in genitourinary tissue defects due to Fournier gangrene: a preliminary trial.
abstract: BACKGROUND
  In these reported cases, we observed the outcomes of skin take and wound healing using 2-octyl-cyanoacrylate glue, which was used as tissue glue in the reconstruction of complex genital skin loss due to fournier gangrene.
  
  
  METHODS
  Fifteen patients with Fournier's gangrene were treated in this study. After initial surgical debridement, all defects were repaired using STSG. In this method a thin layer of 2-octyl-cyanoacrylate was dripped on the recipient site immediately before graft application. All wounds were followed up postoperatively and observed for evidence of graft take, seroma or hematoma formation, drainage, and infection. Patient and physician satisfaction were also determined.
  
  
  RESULTS
  Grafts were completely accepted in all fifteen patients. None of the patients had wound infection, seroma, hematoma, or other complications.
  
  
  CONCLUSIONS
  Use of 2-octyl-cyanoacrylate glue (Glueseal) for STSG fixation in complex genital skin defects after Fournier gangrene may be an acceptable alternative to conventional surgical closure with a good cosmetic outcome. Further studies are needed to confirm our initial success with this approach.
authors.affiliation: Department of Plastic Surgery, Adnan Menderes University Faculty of Medicine, Aydın, Turkey.
authors.forename: Nazan
authors.initials: N
authors.lastname: Sivrioğlu
authors.forename: Saime
authors.initials: S
authors.lastname: Irkören
authors.forename: Ender
authors.initials: E
authors.lastname: Ceylan
authors.forename: Ali Murat
authors.initials: AM
authors.lastname: Sonel
authors.forename: Eray
authors.initials: E
authors.lastname: Copçu
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003487:Cyanoacrylates / Q000008:administration & dosage*; D018934:Fournier Gangrene / Q000601:surgery*; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D016038:Skin Transplantation / Q000379:methods*; D014014:Tissue Adhesives / Q000008:administration & dosage*
chemical_list: D000900:Anti-Bacterial Agents; D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate