title: The importance of early flap coverage in deep sternal wounds.
abstract: BACKGROUND
  Chronic or persistent wound infection is one of the key outcome measures after flap reconstruction in deep sternal wound infection (DSWI). This study aimed to assess potentially modifiable factors associated with chronic infection in patients undergoing flap reconstruction.
  
  
  METHODS
  An analysis of a prospective database of 5239 median sternotomies performed during a 5-year period was carried out. Seventy-seven cases of DSWI were recorded, of which 23 cases proceeded to flap reconstruction. The flap-reconstructed patients were placed into groups according to the primary outcome measure of those who experienced chronic infection and those who remained infection free.
  
  
  RESULTS
  Of the flap-reconstructed patients, 22% experienced subsequent chronic infection, whereas 78% remained infection free. The only 2 variables that were associated with chronic infection were the timing of flap reconstruction; median time 29.5 days (vs 12 days in the infection-free group), P=0.011 and time taken from diagnosis of wound infection/dehiscence to referral to the plastic surgical team; median 21 days (vs median 8 days in the infection free group), P=0.02. Each day of delay from the diagnosis of clinical infection to flap cover equated to an increase in risk of chronic infection of 1.2 times per day (OR=1.205, P=0.039).
  
  
  CONCLUSIONS
  This study suggests that chronic infection after flap reconstruction in DSWI is associated with late flap cover. We suggest the need for a consensus agreement on the combined care and early management of DSWI.
authors.affiliation: From the *Canniesburn Plastic Surgery Unit, Royal Infirmary, Glasgow; †St George's Hospital, Tooting, London; and ‡Queen Alexandra Hospital, Cosham, Portsmouth, Hampshire, United Kingdom.
authors.forename: Steven
authors.initials: S
authors.lastname: Lo
authors.forename: Kristian
authors.initials: K
authors.lastname: Hutson
authors.forename: Marc-James
authors.initials: MJ
authors.lastname: Hallam
authors.forename: Mark
authors.initials: M
authors.lastname: Soldin
mesh_terms: D002908:Chronic Disease; D005500:Follow-Up Studies; D006801:Humans; D017063:Outcome Assessment, Health Care; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D012307:Risk Factors; D056346:Sternotomy; D013524:Surgical Flaps; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control / Q000601:surgery; D013997:Time Factors