title: Limit to benefits of large reductions in low-density lipoprotein cholesterol levels: use of fractional polynomials to assess the effect of low-density lipoprotein cholesterol level reduction in metaregression of large statin randomized trials.
authors.forename: Hisato
authors.initials: H
authors.lastname: Takagi
authors.forename: Takuya
authors.initials: T
authors.lastname: Umemoto
mesh_terms: D008078:Cholesterol, LDL / Q000097:blood*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D015233:Models, Statistical; D016032:Randomized Controlled Trials as Topic; D012044:Regression Analysis
chemical_list: D008078:Cholesterol, LDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors