title: The relationship between vitamin D and PTH levels and cardiovascular risk in the elderly hypertensives.
abstract: OBJECTIVE
  In this study, we aimed to investigate the relationship between vitamin D, parathyroid hormone (PTH) and cardiovascular risk (CVR) in hypertensive patients aged 65 years and over.
  
  
  METHODS
  This study was performed with 84 hypertensive patients and 68 normotensive control group in Afyon Kocatepe University Faculty of Medicine Hospital. The determined cardiovascular risk degrees and the stages of blood pressure were compared with the levels of 25-(OH) vitamin D and PTH.
  
  
  RESULTS
  Mean systolic and diastolic blood pressure (BP) levels of the patients with vitamin D deficiency (VDD) were significantly higher than those without VDD (p<0.001 for both). Mean systolic and diastolic BP levels of the patients with hyperparathyroidism were significantly higher than those without hyperparathyroidism (p=0.012, p=0.036, respectively). CVR was reversely correlated with vitamin D but the correlation with hyperparathyroidism did not reach statistically significant level (r=-0.752, p<0.001) and (r=0.210, p=0.055), respectively.
  
  
  CONCLUSIONS
  These results indicate that the presence of hypertension is associated with VDD, as well as the stage of hypertension contributes to insufficiency, hyperparathyroidism and increased CVR. Clinicians should be aware and perhaps more aggressive for the treatment of HT and VDD in patients over 65 years of age.
authors.affiliation: Department of Internal Medicine and Nephrology .
authors.forename: Sena Memnune
authors.initials: SM
authors.lastname: Ulu
authors.forename: Alper
authors.initials: A
authors.lastname: Ulaslı
authors.forename: Fatima
authors.initials: F
authors.lastname: Yaman
authors.forename: Gökhan
authors.initials: G
authors.lastname: Yaman
authors.forename: Gulay
authors.initials: G
authors.lastname: Ozkececi
authors.forename: Şeref
authors.initials: Ş
authors.lastname: Yuksel
mesh_terms: D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D002318:Cardiovascular Diseases / Q000097:blood* / Q000209:etiology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000097:blood / Q000150:complications; D006973:Hypertension / Q000097:blood* / Q000150:complications*; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood*; D012307:Risk Factors; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications
chemical_list: C470125:PTH protein, human; D010281:Parathyroid Hormone; D014807:Vitamin D; C104450:25-hydroxyvitamin D