title: Comparison of open and laparoscopic appendectomy in uncomplicated appendicitis: a prospective randomized clinical trial.
abstract: BACKGROUND
  In the treatment of a subset of patients with uncomplicated appendicitis, no surgical method has been clearly established as superior.
  
  
  METHODS
  The present study was a prospective randomized clinical trial. Patients diagnosed with acute appendicitis were recruited for the study. Patients with a preoperative diagnosis of complicated appendicitis were excluded. The patients were randomly divided into two groups: a laparoscopic appendectomy group and an open appendectomy group. The primary outcome measure was the rate of postoperative septic complications. Secondary outcome measures were the length of hospital stay, postoperative pain score, and quality of life score.
  
  
  RESULTS
  Ninety-six patients were included in the study, 50 in the laparoscopic appendectomy group and 46 in the open appendectomy group. There were no significant differences between the two groups in terms of the rates of postoperative septic complications, hospital stay lengths, postoperative pain scores, or quality of life scores.
  
  
  CONCLUSIONS
  The laparoscopic approach to appendectomy in patients with uncomplicated appendicitis does not offer a significant advantage over the open approach in terms of length of hospital stay, postoperative pain score, or quality of life, which are considered the major advantages of minimally invasive surgery.
authors.affiliation: Department of General Surgery, Dr. Sadi Konuk Training and Research Hospital, İstanbul, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Kocataş
authors.forename: Murat
authors.initials: M
authors.lastname: Gönenç
authors.forename: Mehmet Abdussamet
authors.initials: MA
authors.lastname: Bozkurt
authors.forename: Mehmet
authors.initials: M
authors.lastname: Karabulut
authors.forename: Eyup
authors.initials: E
authors.lastname: Gemici
authors.forename: Halil
authors.initials: H
authors.lastname: Alış
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001062:Appendectomy / Q000009:adverse effects / Q000379:methods*; D001064:Appendicitis / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000209:etiology; D011446:Prospective Studies; D011788:Quality of Life; D016896:Treatment Outcome; D055815:Young Adult