title: Nationwide surveillance of macrolide-resistant Mycoplasma pneumoniae infection in pediatric patients.
abstract: We conducted nationwide surveillance to investigate regional differences in macrolide-resistant (MR) Mycoplasma pneumoniae strains in Japan. The prevalence of MR M. pneumoniae in pediatric patients gradually increased between 2008 and 2012. Although regional differences were observed, high levels of MR genes were detected in all seven surveillance areas throughout Japan and ranged in prevalence from 50% to 93%. These regional differences were closely related to the previous administration of macrolides.
authors.affiliation: Department of Pediatrics, Kawasaki Medical School, Okayama, Japan.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Kawai
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Miyashita
authors.forename: Mika
authors.initials: M
authors.lastname: Kubo
authors.forename: Hiroto
authors.initials: H
authors.lastname: Akaike
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kato
authors.forename: Yoko
authors.initials: Y
authors.lastname: Nishizawa
authors.forename: Aki
authors.initials: A
authors.lastname: Saito
authors.forename: Eisuke
authors.initials: E
authors.lastname: Kondo
authors.forename: Hideto
authors.initials: H
authors.lastname: Teranishi
authors.forename: Tokio
authors.initials: T
authors.lastname: Wakabayashi
authors.forename: Satoko
authors.initials: S
authors.lastname: Ogita
authors.forename: Takaaki
authors.initials: T
authors.lastname: Tanaka
authors.forename: Kozo
authors.initials: K
authors.lastname: Kawasaki
authors.forename: Takashi
authors.initials: T
authors.lastname: Nakano
authors.forename: Kihei
authors.initials: K
authors.lastname: Terada
authors.forename: Kazunobu
authors.initials: K
authors.lastname: Ouchi
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002648:Child; D024881:Drug Resistance, Bacterial; D004917:Erythromycin / Q000494:pharmacology*; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D009154:Mutation; D009177:Mycoplasma pneumoniae / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification; D011019:Pneumonia, Mycoplasma / Q000453:epidemiology*; D015995:Prevalence; D012141:Respiratory Tract Infections / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D004917:Erythromycin