title: [Effect of ultra high-pressure processing on microorganisms and ginsenosides of Panax ginseng].
abstract: OBJECTIVE
  To study the feasibility of the application of ultra high-pressure processing (UHPP) as an anticorrosion and anti-mould method by comparing the total numbers of bacteria and mould colonies and the content of ginsenosides before and after UHPP.
  
  
  METHODS
  The total numbers of bacteria and moulds colony were determined by microbiological test method. The contents of 12 ginsenosides were determined by HPLC.
  
  
  RESULTS
  Under the three selected conditions, the total number of bacterial colony decreased significantly, while the mould was not detected in UHPP samples; and the contents of 12 ginsenosides were increased significantly in methanol extracts and water extracts.
  
  
  CONCLUSIONS
  UHPP not only shows anticorrosion and anti-mould effects, but also enhances the leaching rate of ginsenosides. It is a highly effective, safe and environmental friendly anticorrosion and anti-mould technique for Ranax ginseng worth in-depth study.
authors.affiliation: Department of Pharmaceutical & Metabolomics, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, China. zhuly818@163.com
authors.forename: Ling-Ying
authors.initials: LY
authors.lastname: Zhu
authors.forename: Yu-De
authors.initials: YD
authors.lastname: Tang
authors.forename: Hong
authors.initials: H
authors.lastname: Shen
authors.forename: Jin-Di
authors.initials: JD
authors.lastname: Xu
authors.forename: Song-Lin
authors.initials: SL
authors.lastname: Li
mesh_terms: D001419:Bacteria / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid; D003343:Corrosion; D005240:Feasibility Studies; D036145:Ginsenosides / Q000032:analysis*; D005894:Panax / Q000737:chemistry* / Q000382:microbiology*; D011312:Pressure
chemical_list: D036145:Ginsenosides