title: Patient autoantibodies induce platelet destruction signals via raft-associated glycoprotein Ibα and Fc RIIa in immune thrombocytopenia.
authors.forename: Rolf T
authors.initials: RT
authors.lastname: Urbanus
authors.forename: Dianne E
authors.initials: DE
authors.lastname: van der Wal
authors.forename: Cornelis A
authors.initials: CA
authors.lastname: Koekman
authors.forename: Albert
authors.initials: A
authors.lastname: Huisman
authors.forename: Dave J
authors.initials: DJ
authors.lastname: van den Heuvel
authors.forename: Hans C
authors.initials: HC
authors.lastname: Gerritsen
authors.forename: Hans
authors.initials: H
authors.lastname: Deckmyn
authors.forename: Jan-Willem N
authors.initials: JW
authors.lastname: Akkerman
authors.forename: Roger E G
authors.initials: RE
authors.lastname: Schutgens
authors.forename: Eelo
authors.initials: E
authors.lastname: Gitz
mesh_terms: D000368:Aged; D001323:Autoantibodies / Q000378:metabolism / Q000502:physiology*; D001792:Blood Platelets / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D008264:Macrophages / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D021962:Membrane Microdomains / Q000276:immunology* / Q000378:metabolism; D019038:Platelet Glycoprotein GPIb-IX Complex / Q000276:immunology* / Q000378:metabolism; D017452:Receptors, IgG / Q000276:immunology* / Q000378:metabolism; D015398:Signal Transduction / Q000276:immunology*; D013921:Thrombocytopenia / Q000097:blood / Q000276:immunology* / Q000473:pathology*
chemical_list: D001323:Autoantibodies; C080568:Fc gamma receptor IIA; D019038:Platelet Glycoprotein GPIb-IX Complex; D017452:Receptors, IgG
keywords: Fc receptor; GPIbα; autoantibodies; immune thrombocytopenia; platelet activation