title: Abnormalities in host defense associated with HIV infection.
abstract: The broad variety of pulmonary infections encountered in human immunodeficiency virus (HIV)-infected individuals demonstrates that the host defense network is impaired. An improved understanding of these events in the lung can lead to specific interventions aimed at restoration of deficient function. This review summarizes the pulmonary host defense deficits in HIV-infected individuals, focusing on lymphocytes, alveolar macrophages, and neutrophils.
authors.affiliation: Medicine Service, Veterans Affairs Eastern Colorado Health Care System, Denver, CO 80220, USA. james.beck@ucdenver.edu
authors.forename: James M
authors.initials: JM
authors.lastname: Beck
mesh_terms: D015658:HIV Infections / Q000276:immunology*; D006801:Humans; D008168:Lung / Q000276:immunology*; D008171:Lung Diseases / Q000276:immunology; D008214:Lymphocytes / Q000502:physiology*; D016676:Macrophages, Alveolar / Q000502:physiology; D009504:Neutrophils / Q000502:physiology