title: Humoral response and colostral antibody transfer following 'one-dose' pre-mating vaccination of sows against porcine circovirus type-2.
abstract: The objective of this study was to investigate the presence of porcine circovirus type 2 (PCV2) DNA and antibody to the virus in the serum and colostrum of sows vaccinated prior to mating and in their offspring. Seventy-seven sows were randomly distributed into vaccinated (V, n=36) and non-vaccinated (NV, n=41) groups. One week before mating, sows were given a PCV2 vaccine (V group) or PBS (NV group) IM. Blood samples were taken from the sows at fixed time-points and colostrum samples were taken at farrowing. Blood samples were also taken from the piglets of the sows at 4 weeks of age. The results indicated that vaccination prior to mating elicited a strong, homogeneous humoral response and, in consequence, more homogeneous colostral PCV2 antibody concentrations.
authors.affiliation: Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Campus de la Universitat Autònoma de Barcelona, 08193 Bellaterra (Cerdanyola del Vallés), Spain.
authors.forename: M
authors.initials: M
authors.lastname: Sibila
authors.forename: L
authors.initials: L
authors.lastname: Fraile
authors.forename: G
authors.initials: G
authors.lastname: Ticó
authors.forename: S
authors.initials: S
authors.lastname: López-Soria
authors.forename: M
authors.initials: M
authors.lastname: Nofrarías
authors.forename: E
authors.initials: E
authors.lastname: Huerta
authors.forename: A
authors.initials: A
authors.lastname: Llorens
authors.forename: R
authors.initials: R
authors.lastname: López-Jiménez
authors.forename: D
authors.initials: D
authors.lastname: Pérez
authors.forename: J
authors.initials: J
authors.lastname: Segalés
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood / Q000737:chemistry / Q000276:immunology*; D018173:Circoviridae Infections / Q000517:prevention & control / Q000662:veterinary / Q000821:virology; D017925:Circovirus / Q000145:classification* / Q000276:immunology; D003126:Colostrum / Q000737:chemistry*; D005260:Female; D056724:Immunity, Humoral; D007112:Immunity, Maternally-Acquired; D011247:Pregnancy; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines
keywords: Antibody transfer; Colostrum; Porcine circovirus type-2 (PCV2); Sow; Vaccination