title: Detection of masked mycotoxins derived from type A trichothecenes in corn by high-resolution LC-Orbitrap mass spectrometer.
abstract: Masked mycotoxins (mycotoxin glucosides) derived from type A trichothecenes were detected in commercially available corn powder reference material. These new glucosides were identified as neosolaniol-glucoside (NESGlc) and diacetoxyscirpenol-glucoside (DASGlc) on the basis of accurate mass measurements of characteristic ions and fragmentation patterns using high-resolution liquid chromatography-Orbitrap mass spectrometric (LC-Orbitrap MS) analysis. Although the absolute structure was not clarified, 3-OH glucosylation appeared to be the most probable when considering the structures of neosolaniol and diacetoxyscirpenol and the fragmentation profiles of these masked mycotoxins. Concomitant detection of deoxynivalenol-3-glucoside, the most well-known masked mycotoxin derived from the type B trichothecene, deoxynivalenol, in the identical material further supports this probability.
authors.affiliation: National Agriculture and Food Research Organization (NARO), National Food Research Institute, Tsukuba-shi, Ibaraki, Japan. hironkgw@affrc.go.jp
authors.forename: H
authors.initials: H
authors.lastname: Nakagawa
authors.forename: S
authors.initials: S
authors.lastname: Sakamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Sago
authors.forename: M
authors.initials: M
authors.lastname: Kushiro
authors.forename: H
authors.initials: H
authors.lastname: Nagashima
mesh_terms: D000818:Animals; D005504:Food Analysis / Q000295:instrumentation / Q000379:methods; D005506:Food Contamination; D005960:Glucosides / Q000737:chemistry; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods*; D015394:Molecular Structure; D009183:Mycotoxins / Q000737:chemistry*; D014255:Trichothecenes / Q000737:chemistry*; D003313:Zea mays / Q000737:chemistry*
chemical_list: D005960:Glucosides; D009183:Mycotoxins; D014255:Trichothecenes; C587042:diacetoxyscirpenol-glucoside; C587041:neosolaniol-glucoside