title: Common anatomical variation in patients with idiopathic meralgia paresthetica: a high resolution ultrasound case-control study.
abstract: BACKGROUND
  Meralgia paresthetica (MP) is a mononeuropathy of the lateral femoral cutaneous nerve (LFCN) characterized by pain, numbness or paresthesia on the anterolateral aspect of the thigh. Though several contributing factors have been identified, the cause of its idiopathic form still remains unclear. Anatomic and clinical studies have demonstrated a variable course for the LFCN and have suggested a contribution to the pathogenesis of MP.
  
  
  OBJECTIVE
  It was the aim of the present case-control study to assess the anatomical course and compression site of the LFCN using high resolution ultrasound (HRUS) in patients suffering from idiopathic MP, and compare the anatomical course in these patients to an asymptomatic control group.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  Nerve imaging center at a large university hospital in Austria.
  
  
  METHODS
  Twenty-eight patients with a diagnosis of MP were included in this study (20 men, 8 women; mean age 54 years). The diagnosis was established by clinical history, physical examination, and diagnostic anesthetic block. Fifteen age- and gender-matched healthy volunteers served as the control group. Standardized HRUS examinations were performed by one experienced radiologist from June 2004 through April 2012. Two experienced radiologists reviewed the patients' standardized HRUS examinations and performed examinations in the control group to measure the minimal distance between the LFCN and the anterior superior iliac spine (ASIS).
  
  
  RESULTS
  The minimal distance between the ASIS and the LFCN was measured using HRUS.
  
  
  RESULTS
  The LFCN could be seen in all patients and volunteers. In MP patients, the mean distance between the LFCN and the ASIS was 0.52 cm (SD 0.46 cm), compared to a mean distance of 1.79 cm (SD 1.48 cm) in the control group (P < 0.001).
  
  
  CONCLUSIONS
  Limited sample size, retrospective design.
  
  
  CONCLUSIONS
  The results of this study demonstrate a significantly different course of the LFCN, closer to the ASIS in patients with idiopathic MP.
authors.affiliation: Department of Radiology, Medical University of Vienna A-1090 Vienna, Austria. thomas.moritz@meduniwien.ac.at
authors.forename: Thomas
authors.initials: T
authors.lastname: Moritz
authors.forename: Helmut
authors.initials: H
authors.lastname: Prosch
authors.forename: Dominik
authors.initials: D
authors.lastname: Berzaczy
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Happak
authors.forename: Doris
authors.initials: D
authors.lastname: Lieba-Samal
authors.forename: Maria
authors.initials: M
authors.lastname: Bernathova
authors.forename: Eduard
authors.initials: E
authors.lastname: Auff
authors.forename: Gerd
authors.initials: G
authors.lastname: Bodner
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D016022:Case-Control Studies; D005260:Female; D020428:Femoral Neuropathy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009408:Nerve Compression Syndromes / Q000000981:diagnostic imaging* / Q000473:pathology*; D010147:Pain Measurement; D012189:Retrospective Studies; D014463:Ultrasonography