title: Ibuprofen-induced hemolytic anemia.
abstract: Drug-induced immune hemolytic anemia is a rare condition with an incidence of 1 per million of the population. We report the case of a 36-year-old female who presented to the emergency department complaining of shortness of breath and dark colored urine. Physical examination was significant for pale mucous membranes. The patient reported using ibuprofen for a few days prior to presentation. Complete blood count performed before starting ibuprofen revealed normal platelets and hemoglobin values. On admission, the patient had evidence of hemolytic anemia with hemoglobin of 4.9 g/dL, hematocrit of 14.2%, lactate dehydrogenase 435 IU/L, and reticulocytosis 23.2%. Further testing ruled out autoimmune disease, lymphoma, and leukemia as etiologies for the patient's new onset hemolytic anemia. Ibuprofen was immediately stopped with a gradual hematologic recovery within 3 days.
authors.affiliation: Department of Internal Medicine, Saint Joseph Hospital, 2900 N. Lake Shore, Chicago, IL 60657, USA.
authors.forename: Aram
authors.initials: A
authors.lastname: Barbaryan
authors.forename: Chioma
authors.initials: C
authors.lastname: Iyinagoro
authors.forename: Nwabundo
authors.initials: N
authors.lastname: Nwankwo
authors.forename: Alaa M
authors.initials: AM
authors.lastname: Ali
authors.forename: Raya
authors.initials: R
authors.lastname: Saba
authors.forename: Shawn G
authors.initials: SG
authors.lastname: Kwatra
authors.forename: Nasir
authors.initials: N
authors.lastname: Hussain
authors.forename: Chukwuemeka C
authors.initials: CC
authors.lastname: Uzoka
authors.forename: Suartcha
authors.initials: S
authors.lastname: Prueksaritanond
authors.forename: Aibek E
authors.initials: AE
authors.lastname: Mirrakhimov