title: Newer imaging modalities in the assessment of heart function in single ventricle hearts.
abstract: The limitations of geometry assumptions in 2-dimensional echocardiographic assessment of the single ventricle (SV) have been overcome by recent advances in 3-D echocardiography. Improved reproducibility for measuring ventricular volumes and ejection fraction using 3-D echocardiography makes it ideally suited for serial monitoring of SV systolic function and should be considered in routine echocardiography imaging protocols for SV. The moderate correlation of Doppler derived E/e' ratio with invasive ventricular end diastolic pressure in SV, suggests it might be useful in the assessment of SV diastolic function. Speckle tracking imaging is intensely studied and promises to be a simple and repeatable imaging tool for quantifying SV function. In contrast, the advances in cardiac magnetic resonance imaging techniques promise to offer insights into the pathogenesis of myocardial dysfunction in SV. Late gadolinium enhancement imaging is a robust tool in assessing macroscopic myocardial scarring and T1 mapping and stress perfusion imaging are newer modalities that might improve understanding of the mechanisms in progressive myocardial dysfunction in SV hearts.
authors.affiliation: Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada. khoo@ualberta.ca
authors.forename: Nee Scze
authors.initials: NS
authors.lastname: Khoo
authors.forename: Edythe B
authors.initials: EB
authors.lastname: Tham
authors.forename: Paul F
authors.initials: PF
authors.lastname: Kantor
mesh_terms: D000328:Adult; D057791:Cardiac Imaging Techniques / Q000379:methods*; D002648:Child; D004452:Echocardiography / Q000379:methods; D006330:Heart Defects, Congenital / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D016276:Ventricular Function / Q000502:physiology*