title: A case report of a patient with advanced acinar cell carcinoma of the pancreas: long-term survival with regional, systemic and targeted therapy.
abstract: Acinar cell carcinoma of the pancreas is an uncommon malignancy for which there are no prospective, randomized data to guide therapy. We describe the clinical course and management of a patient with advanced pancreatic acinar cell carcinoma who is alive seven years after diagnosis using systemic and regional chemotherapies as well as molecularly targeted agents.
authors.affiliation: Department of Medicine, Gastrointestinal Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
authors.forename: Celina
authors.initials: C
authors.lastname: Ang
authors.forename: Luis A
authors.initials: LA
authors.lastname: Herran
authors.forename: Diane Reidy
authors.initials: DR
authors.lastname: Lagunes
authors.forename: David S
authors.initials: DS
authors.lastname: Klimstra
authors.forename: Nancy E
authors.initials: NE
authors.lastname: Kemeny
mesh_terms: D000368:Aged; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D000068258:Bevacizumab; D014408:Biomarkers, Tumor / Q000032:analysis; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D018267:Carcinoma, Acinar Cell / Q000737:chemistry / Q000175:diagnosis* / Q000188:drug therapy* / Q000556:secondary; D000068818:Cetuximab; D019788:Fluorodeoxyglucose F18; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007150:Immunohistochemistry; D002955:Leucovorin / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000737:chemistry / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D058990:Molecular Targeted Therapy; D064847:Multimodal Imaging / Q000379:methods; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D010190:Pancreatic Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D014408:Biomarkers, Tumor; D009944:Organoplatinum Compounds; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D000068258:Bevacizumab; D000068818:Cetuximab; D002955:Leucovorin; D005472:Fluorouracil; D002166:Camptothecin