title: Current status of bone graft options for anterior interbody fusion of the cervical and lumbar spine.
abstract: Anterior cervical discectomy and fusion (ACDF) and anterior lumbar interbody fusion (ALIF) are common surgical procedures for degenerative disc disease of the cervical and lumbar spine. Over the years, many bone graft options have been developed and investigated aimed at complimenting or substituting autograft bone, the traditional fusion substrate. Here, we summarise the historical context, biological basis and current best evidence for these bone graft options in ACDF and ALIF.
authors.affiliation: Department of Neurosurgery, Royal Prince Alfred Hospital, Sydney, Australia.
authors.forename: Anthony Minh Tien
authors.initials: AM
authors.lastname: Chau
authors.forename: Lileane Liang
authors.initials: LL
authors.lastname: Xu
authors.forename: Johnny Ho-Yin
authors.initials: JH
authors.lastname: Wong
authors.forename: Ralph Jasper
authors.initials: RJ
authors.lastname: Mobbs
mesh_terms: D001846:Bone Development; D016026:Bone Marrow Transplantation / Q000379:methods; D018786:Bone Substitutes; D016025:Bone Transplantation / Q000191:economics / Q000379:methods*; D002574:Cervical Vertebrae / Q000601:surgery*; D019317:Evidence-Based Medicine; D015316:Genetic Therapy; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery*; D013123:Spinal Fusion / Q000191:economics / Q000379:methods*
chemical_list: D018786:Bone Substitutes