title: Laryngeal leiomyosarcoma masquerading as laryngeal carcinoma.
abstract: Laryngeal leiomyosarcoma is an exceedingly rare malignant tumour, with fewer than 50 reported cases in scientific literature. Diagnosis is based on immunohistochemistry, supplemented with ultrastructural studies, if required. It is aggressive and associated with variable survival outcomes. A 63-year-old man presented with hoarseness for 7 months and breathlessness for 3 months. Imaging showed a well-defined 3 cm glottic mass. Total laryngectomy was performed. The histopathological examination showed features of leiomyosarcoma. The index case has been presented owing to its rarity, variable clinical manifestations and diagnostic dilemmas and to stress upon the importance of ancillary techniques for confirmation.
authors.affiliation: Department of Pathology, All India Institute of Medical Sciences, New Delhi, Delhi, India.
authors.forename: Lavleen
authors.initials: L
authors.lastname: Singh
authors.forename: Saumyaranjan
authors.initials: S
authors.lastname: Mallick
authors.forename: Shuchita
authors.initials: S
authors.lastname: Singh
authors.forename: Rajni
authors.initials: R
authors.lastname: Safaya
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis*; D007890:Leiomyosarcoma / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome