title: The correlation of serum NT-proBNP levels of hemorrhagic and ischemic lesions detected with diffusion MRI in head traumas.
abstract: OBJECTIVE
  To evaluate the correlation between the dimensions of ischemic and hemorrhagic lesions detected by diffusion MRI and the changes in lesion dimensions with serum NT-proBNP levels in mild and moderate head trauma.
  
  
  METHODS
  30 patients were assessed in our study. A control group of 10 individuals with no trauma history was formed in order to establish normal serum NT-proBNP values. Patients underwent brain diffusion MRI 24 and 48 hours following admittance. Their plasma NT-proBNP levels were checked at the same stages.
  
  
  RESULTS
  The correlation between the values of 24th and 48th hour Intra-axial hemorrhage (IAHEM) and Intra-axial ischemia (IAISC) and the values of 24th and 48th hour NT-proBNP was established as statistically significant.
  
  
  CONCLUSIONS
  It was observed that the serum NT-proBNP values could be higher in patients with wide intra-axial lesion following head trauma than patients with smaller intra-axial lesions. In addition, the fact that it has been established that the serum NT-proBNP values of patients with increasing cerebral parenchymal lesion dimensions on the advancing hours after the trauma increase suggests that serum NTproBNP values may be significant in the follow-up of the dimensions of cerebral parenchymal damage.
authors.affiliation: Yuksekova State Hospital, Department of Neurosurgery, Hakkari, Turkey. bekirakgun@yahoo.com
authors.forename: Bekir
authors.initials: B
authors.lastname: Akgun
authors.forename: Fatih Serhat
authors.initials: FS
authors.lastname: Erol
authors.forename: Hanefi
authors.initials: H
authors.lastname: Yildirim
authors.forename: Nevin
authors.initials: N
authors.lastname: Ilhan
authors.forename: Metin
authors.initials: M
authors.lastname: Kaplan
mesh_terms: D000328:Adult; D002543:Cerebral Hemorrhage / Q000473:pathology*; D006259:Craniocerebral Trauma / Q000175:diagnosis / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D005260:Female; D006801:Humans; D007511:Ischemia / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood* / Q000378:metabolism; D055815:Young Adult
chemical_list: D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain