title: Combined kidney and intestinal transplantation in patients with enteric hyperoxaluria secondary to short bowel syndrome.
abstract: Kidney transplantation is the treatment of choice for end-stage renal disease whereas indications for intestinal transplantation are currently restricted to patients with irreversible small bowel failure and severe complications of total parenteral nutrition (mostly shortage and infection of venous accesses, major electrolyte disturbances and liver failure). Enteric hyperoxaluria is secondary to certain intestinal diseases like intestinal resections, chronic inflammatory bowel disease and other malabsorption syndromes and can lead to end-stage renal disease requiring kidney transplantation. We report two patients suffering from renal failure due to enteric hyperoxaluria (secondary to extensive intestinal resection) in whom we elected to replace not only the kidney but also the intestine to prevent recurrence of hyperoxaluria in the transplanted kidney.
authors.affiliation: Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium.
authors.forename: L J
authors.initials: LJ
authors.lastname: Ceulemans
authors.forename: Y
authors.initials: Y
authors.lastname: Nijs
authors.forename: F
authors.initials: F
authors.lastname: Nuytens
authors.forename: G
authors.initials: G
authors.lastname: De Hertogh
authors.forename: K
authors.initials: K
authors.lastname: Claes
authors.forename: B
authors.initials: B
authors.lastname: Bammens
authors.forename: M
authors.initials: M
authors.lastname: Naesens
authors.forename: P
authors.initials: P
authors.lastname: Evenepoel
authors.forename: D
authors.initials: D
authors.lastname: Kuypers
authors.forename: Y
authors.initials: Y
authors.lastname: Vanrenterghem
authors.forename: D
authors.initials: D
authors.lastname: Monbaliu
authors.forename: J
authors.initials: J
authors.lastname: Pirenne
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006959:Hyperoxaluria / Q000150:complications / Q000601:surgery*; D007421:Intestine, Small / Q000637:transplantation*; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery*; D016030:Kidney Transplantation / Q000379:methods*; D008875:Middle Aged; D012778:Short Bowel Syndrome / Q000150:complications / Q000601:surgery*