title: Evaluation of the differentiation status of single embryonic stem cells using scanning electrochemical microscopy.
abstract: The differentiation status of single live embryonic stem (ES) cells was quantitatively evaluated by monitoring the activity of alkaline phosphatase (ALP), an undifferentiation marker of ES cells, using scanning electrochemical microscopy (SECM).
authors.affiliation: Graduate School of Environmental Studies, Tohoku University, Aramaki 6-6-11-605, Aoba, Sendai 980-8579, Japan.
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Matsumae
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Arai
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Kosuke
authors.initials: K
authors.lastname: Ino
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Shiku
authors.forename: Tomokazu
authors.initials: T
authors.lastname: Matsue
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D002454:Cell Differentiation; D002478:Cells, Cultured; D053595:Embryonic Stem Cells / Q000166:cytology* / Q000378:metabolism*; D051379:Mice; D064347:Microscopy, Electrochemical, Scanning; D059010:Single-Cell Analysis / Q000379:methods*; D014212:Tretinoin / Q000494:pharmacology
chemical_list: D014212:Tretinoin; D000469:Alkaline Phosphatase