title: Deformable medical image registration: a survey.
abstract: Deformable image registration is a fundamental task in medical image processing. Among its most important applications, one may cite: 1) multi-modality fusion, where information acquired by different imaging devices or protocols is fused to facilitate diagnosis and treatment planning; 2) longitudinal studies, where temporal structural or anatomical changes are investigated; and 3) population modeling and statistical atlases used to study normal anatomical variability. In this paper, we attempt to give an overview of deformable registration methods, putting emphasis on the most recent advances in the domain. Additional emphasis has been given to techniques applied to medical images. In order to study image registration methods in depth, their main components are identified and studied independently. The most recent techniques are presented in a systematic fashion. The contribution of this paper is to provide an extensive account of registration techniques in a systematic manner.
authors.affiliation: Section of Biomedical Image Analysis, Center for Biomedical Image Computing and Analytics, Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA. aristieidis.sotiras@uphs.upenn.edu
authors.forename: Aristeidis
authors.initials: A
authors.lastname: Sotiras
authors.forename: Christos
authors.initials: C
authors.lastname: Davatzikos
authors.forename: Nikos
authors.initials: N
authors.lastname: Paragios
mesh_terms: D000465:Algorithms; D003952:Diagnostic Imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted