title: Organocatalytic asymmetric annulation of 1,3-bis(alkoxycarbonyl)buta-1,3-dienes and aldehydes.
abstract: Asymmetric organocatalytic annulation of E/Z isomeric mixtures of bis(alkyl carboxylate)buta-1,3-dienes and aldehydes has been realized via enamine catalysis. In the presence of α,α-diphenyl-2-pyrrolidinemethanol trimethylsilyl ether, excellent stereo- and enantioselectivities were achieved for a broad spectrum of substrates.
authors.affiliation: Department of Organic Chemistry, University of Geneva , quai Ernest Ansermet 30, CH-1211 Geneva 4, Switzerland, Istituto di Chimica dei Composti Organometallici , ICCOM-CNR, via Madonna del Piano 10, Sesto Fiorentino - (Fi), 50019 Italy, Department of Chemistry, National University of Ireland Maynooth , County Kildare, Ireland, and Laboratory of Crystallography, University of Geneva , quai Ernest Ansermet 24, CH-1211 Geneva 4, Switzerland.
authors.forename: Bernardo
authors.initials: B
authors.lastname: Pezzati
authors.forename: Mathieu F
authors.initials: MF
authors.lastname: Chellat
authors.forename: John J
authors.initials: JJ
authors.lastname: Murphy
authors.forename: Céline
authors.initials: C
authors.lastname: Besnard
authors.forename: Gianna
authors.initials: G
authors.lastname: Reginato
authors.forename: John C
authors.initials: JC
authors.lastname: Stephens
authors.forename: Alexandre
authors.initials: A
authors.lastname: Alexakis