title: Transplanting pediatric deceased-donor kidneys into adult recipients: an Iranian experience.
abstract: OBJECTIVE
  This study sought to evaluate graft outcome of kidneys from deceased-donor pediatric donors in adult recipients, and compare it with outcomes of kidney transplants from adult donors.
  
  
  METHODS
  This historical cohort study involved 2 groups. Group 1 included 23 first kidney adult recipients who received their first renal transplant from pediatric deceased-donor donors. Group 2 consisted of 33 first renal transplant adult recipients with kidneys coming from adult deceased donors. The Kaplan-Meier method was used to generate graft survival and patient survival curves. The log-rank test was done to compare differences between survival outcomes.
  
  
  RESULTS
  Graft survival rates at 1 and 5 years were 96% and 85% in group 1, and 91% and 85% in group 2. No significant difference existed in graft survival rates between the groups. Patient survival rates at 1 and 5 years in group 1 were 94% and 94% compared with 91% and 91% for group 2. No significant difference existed in graft survival rates between the groups.
  
  
  CONCLUSIONS
  This study demonstrates that with our experience, improvement in surgical technique and immunosuppressive therapy, pediatric deceased-donor kidneys may be considered as an alternate option for adult recipients. Renal transplants from pediatric donors into adult recipients is associated with good graft and patient survival outcomes.
authors.affiliation: Department of Urology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Mahdavi-Zafarghandi
authors.forename: Behnam
authors.initials: B
authors.lastname: Shakiba
authors.forename: Kazem
authors.initials: K
authors.lastname: Heidari
authors.forename: Farnaz
authors.initials: F
authors.lastname: Kalani-Moghaddam
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D046148:Donor Selection; D006085:Graft Survival; D006801:Humans; D007492:Iran; D053208:Kaplan-Meier Estimate; D016030:Kidney Transplantation / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult