title: A rotaxane turing machine for peptides.
abstract: A ringing belt: An artificial molecular machine was invented to build up a programmable peptidic sequence. By molecular movements, the rotaxane-based machine progressively introduces amino acids to form a short peptide chain. The journey towards an artificial ribosome is still quite long, but a conceivable future can be envisaged.
authors.affiliation: Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Dublin 4, Ireland.
authors.forename: Claire Margaret
authors.initials: CM
authors.lastname: Wilson
authors.forename: Andrea
authors.initials: A
authors.lastname: Gualandi
authors.forename: Pier Giorgio
authors.initials: PG
authors.lastname: Cozzi
mesh_terms: D000595:Amino Acid Sequence; D015394:Molecular Structure; D010455:Peptides / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D012270:Ribosomes / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D043862:Rotaxanes / Q000737:chemistry* / Q000378:metabolism
chemical_list: D010455:Peptides; D043862:Rotaxanes
keywords: molecular machines; peptides; ribosomes; rotaxanes