title: Neonatal transfusion-transmitted hepatitis C virus infection following a pre-seroconversion window-phase donation in Sweden.
abstract: A 9-day-old child developed a transfusion-transmitted hepatitis C virus (HCV) infection following a pre-seroconversion window-phase donation. Retrospective analysis of donor plasma revealed detectable HCV core antigen (154 fmol/l), as well as HCV RNA (87,000 IU/ml). Of 5.24 million Swedish plasma samples from December 1998 to September 2012, 5 additional window-phase donations were identified.
authors.affiliation: From the Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg.
authors.forename: Jesper
authors.initials: J
authors.lastname: Waldenström
authors.forename: Jan
authors.initials: J
authors.lastname: Konar
authors.forename: Bengt
authors.initials: B
authors.lastname: Ekermo
authors.forename: Helene
authors.initials: H
authors.lastname: Norder
authors.forename: Martin
authors.initials: M
authors.lastname: Lagging
mesh_terms: D006526:Hepatitis C / Q000175:diagnosis* / Q000635:transmission*; D018936:Hepatitis C Antigens / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010949:Plasma / Q000821:virology; D012367:RNA, Viral / Q000097:blood; D013548:Sweden; D065227:Transfusion Reaction; D014758:Viral Core Proteins / Q000097:blood
chemical_list: D018936:Hepatitis C Antigens; D012367:RNA, Viral; D014758:Viral Core Proteins; C499352:core protein p22, Hepatitis C virus