title: In rare acute myeloid leukemia patients harboring both RUNX1 and NPM1 mutations, RUNX1 mutations are unusual in structure and present in the germline.
authors.forename: Jason H
authors.initials: JH
authors.lastname: Mendler
authors.forename: Kati
authors.initials: K
authors.lastname: Maharry
authors.forename: Heiko
authors.initials: H
authors.lastname: Becker
authors.forename: Ann-Kathrin
authors.initials: AK
authors.lastname: Eisfeld
authors.forename: Leigha
authors.initials: L
authors.lastname: Senter
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Mrózek
authors.forename: Jessica
authors.initials: J
authors.lastname: Kohlschmidt
authors.forename: Klaus H
authors.initials: KH
authors.lastname: Metzeler
authors.forename: Sebastian
authors.initials: S
authors.lastname: Schwind
authors.forename: Susan P
authors.initials: SP
authors.lastname: Whitman
authors.forename: Jihane
authors.initials: J
authors.lastname: Khalife
authors.forename: Michael A
authors.initials: MA
authors.lastname: Caligiuri
authors.forename: Rebecca B
authors.initials: RB
authors.lastname: Klisovic
authors.forename: Joseph O
authors.initials: JO
authors.lastname: Moore
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Carter
authors.forename: Guido
authors.initials: G
authors.lastname: Marcucci
authors.forename: Clara D
authors.initials: CD
authors.lastname: Bloomfield
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D050676:Core Binding Factor Alpha 2 Subunit / Q000235:genetics*; D005260:Female; D018095:Germ-Line Mutation / Q000235:genetics*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis* / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009687:Nuclear Proteins / Q000235:genetics*; D000090243:Nucleophosmin
chemical_list: D050676:Core Binding Factor Alpha 2 Subunit; C000716967:NPM1 protein, human; D009687:Nuclear Proteins; C493728:RUNX1 protein, human; D000090243:Nucleophosmin
keywords: NPM1; RUNX1; acute myeloid leukemia; mutational interrelationships; mutations