title: Endothelial progenitor cells and atherosclerosis.
abstract: Atherosclerosis is due to inflammation and endothelial dysfunction and damage caused by a variety of factors. Dysfunction of endothelial progenitor cells (EPCs) that differentiate into mature endothelial cell contributes to the development of atherosclerosis. Both the number and functionality of EPCs are regulated, particularly in vascular repair. Further elucidation of the role of EPCs in atherosclerosis could potentially enable the development of novel strategies for prevention and treatment of pathological changes in atherosclerosis.
authors.affiliation: Department of Cardiology, the 8th Renmin Hospital, Shanghai, Shanghai, China. ruancw2012@yeah.net
authors.forename: Changwu
authors.initials: C
authors.lastname: Ruan
authors.forename: Yan
authors.initials: Y
authors.lastname: Shen
authors.forename: Rui
authors.initials: R
authors.lastname: Chen
authors.forename: Zhancheng
authors.initials: Z
authors.lastname: Wang
authors.forename: Jin
authors.initials: J
authors.lastname: Li
authors.forename: Yun
authors.initials: Y
authors.lastname: Jiang
mesh_terms: D050197:Atherosclerosis / Q000473:pathology*; D004730:Endothelium, Vascular / Q000473:pathology*; D006801:Humans; D013234:Stem Cells / Q000166:cytology*