title: Pd(OAc)2-catalyzed regioselective aromatic C-H bond fluorination.
abstract: A novel Pd(OAc)2-NFSI-TFA system was developed for the highly selective ortho-monofluorination directed by diverse aryl-N-heterocyclic directing groups e.g., quinoxaline, pyrazole, benzo[d]oxazole, and pyrazine derivatives. A Pd(II/IV) catalytic cycle was proposed based on the ESI-MS/MS studies.
authors.affiliation: Catalytic Hydrogenation Research Center, State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Zhejiang University of Technology, Hangzhou 310014, PR China.
authors.forename: Shao-Jie
authors.initials: SJ
authors.lastname: Lou
authors.forename: Dan-Qian
authors.initials: DQ
authors.lastname: Xu
authors.forename: Ai-Bao
authors.initials: AB
authors.lastname: Xia
authors.forename: Yi-Feng
authors.initials: YF
authors.lastname: Wang
authors.forename: Yun-Kui
authors.initials: YK
authors.lastname: Liu
authors.forename: Xiao-Hua
authors.initials: XH
authors.lastname: Du
authors.forename: Zhen-Yuan
authors.initials: ZY
authors.lastname: Xu