title: [Clinical characteristics of multiple myeloma involving sphenoid sinus].
abstract: OBJECTIVE
  To study the clinical characteristics, diagnosis and management of multiple myeloma involving sphenoid sinus.
  
  
  METHODS
  The clinical data of 2 patients with multiple myeloma involving sphenoid sinus were reported and the relevant literatures were also reviewed.
  
  
  RESULTS
  Diplopia and headache were the common symptoms of the patients, and there were also some symptoms related to other organs. Patients often had repeated medical treatments and were finally diagnosed by the biopsy of sphenoid sinus. The disease progressed rapidly in the young patient.
  
  
  CONCLUSIONS
  Characteristics of multiple myeloma are complicated. Biopsy of the sphenoid sinus is meaningful for patients with both sphenoid sinus tumor and systematic symptoms, especially those with rapid progress.
authors.affiliation: Center of Otolaryngology-Head and Neck Surgery, People's Liberty Army, Beijing Naval General Hospital, Beijing, 100048, China.
authors.forename: Ya
authors.initials: Y
authors.lastname: Liu
authors.forename: Jianjun
authors.initials: J
authors.lastname: Sun
authors.forename: Houen
authors.initials: H
authors.lastname: Li
authors.forename: Jin
authors.initials: J
authors.lastname: Qian
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000473:pathology; D010255:Paranasal Sinus Neoplasms / Q000473:pathology / Q000556:secondary; D012189:Retrospective Studies; D013101:Sphenoid Sinus / Q000473:pathology