title: [Mediastinal sarcoidosis in an oncologic context: role of endoscopic ultrasound-guided fine needle aspiration].
abstract: BACKGROUND
  Sarcoidosis and sarcoid reactions have been previously reported in association with cancer. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is a minimally invasive test for investigating mediastinal lymph nodes
  
  
  METHODS
  We conducted a retrospective review of 54 patients undergoing EUS-FNA in a cancer institute for suspected metastatic mediastinal lymph nodes showed by CT-imaging or positron emission tomography (PET). Patients with non-caseating granuloma identified by EUS-FNA were included
  
  
  RESULTS
  EUS-FNA identified non-caseating granuloma in seven out of the 54 included patients. Most of them had positive PET. One patient had a prior history of sarcoidosis before the diagnosis of cancer. Another patient developed micrometastasis associated with sarcoid-like reaction. There was no adverse outcome associated with the EUS-FNA procedure
  
  
  CONCLUSIONS
  Sarcoidosis must be included in the differential diagnosis of patients with a history of malignancy who develop mediastinal lymphadenopathy. EUS-FNA is a safe and minimally invasive test to obtain tissue diagnosis.
authors.affiliation: Département d'oncologie médicale, institut Bergonié, 229, cours de l'Argonne, 33076 Bordeaux, France. Electronic address: dominique.bechade94@orange.fr.
authors.forename: D
authors.initials: D
authors.lastname: Béchade
authors.forename: G
authors.initials: G
authors.lastname: Roubaud
authors.forename: D
authors.initials: D
authors.lastname: Garbay
authors.forename: I
authors.initials: I
authors.lastname: Soubeyran
authors.forename: S
authors.initials: S
authors.lastname: Hé
authors.forename: A-L
authors.initials: AL
authors.lastname: Cazeau
authors.forename: M
authors.initials: M
authors.lastname: Desjardin
authors.forename: M
authors.initials: M
authors.lastname: Fonck
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008477:Mediastinal Diseases / Q000473:pathology*; D008479:Mediastinal Neoplasms / Q000473:pathology*; D008875:Middle Aged; D012189:Retrospective Studies; D012507:Sarcoidosis / Q000473:pathology*
keywords: Cancer; Endoscopic ultrasound; Mediastinum; Médiastin; Sarcoidosis; Sarcoïdose; Échoendoscopie