title: Much remains to be learned about how UVR induces mutations.
abstract: Data on the wavelength dependence of UV-induced formation of DNA damage and skin cancer have been available for quite some time, but a detailed in vivo action spectrum of mutation formation has not yet been reported so far. This important information gap is filled by Ikehata et al. in this issue. Their findings question several aspects of our current thinking about UV-induced mutagenesis and carcinogenesis.
authors.affiliation: Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts 02118, USA. USA. truenger@bu.edu
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Rünger
mesh_terms: D000818:Animals; D004890:Erythema / Q000209:etiology* / Q000235:genetics*; D009154:Mutation / Q000235:genetics*; D012867:Skin / Q000528:radiation effects*; D013057:Spectrum Analysis; D014466:Ultraviolet Rays / Q000009:adverse effects*