title: Ozone-induced caspase-like activities are dependent on early ion channel regulations and ROS generation in Arabidopsis thaliana cells.
abstract: Using A. thaliana cultured cells; we recently reported new insights regarding the effect of acute O₃ exposure. This consist in an oxidative dependent controlled cell death process involving cell shrinkage due to an early activation of anion channel (1) and a delayed activation of K(+) outward currents, but also to early events like Ca (2+) influx or singlet oxygen production possibly linked to mitochondrial dysfunction. Here we provide evidence that most of these early events act downstream of caspase-like activities as recently demonstrated for K(+) channel activation.
authors.affiliation: Univ Paris Diderot, Sorbonne Paris Cité; Institut des Energies de Demain (IED, FRE 3597); Paris, France; Institut de Biologie des Plantes; Orsay, France.
authors.forename: Daniel
authors.initials: D
authors.lastname: Tran
authors.forename: Marika
authors.initials: M
authors.lastname: Rossi
authors.forename: Bernadette
authors.initials: B
authors.lastname: Biligui
authors.forename: Tomonori
authors.initials: T
authors.lastname: Kawano
authors.forename: Stefano
authors.initials: S
authors.lastname: Mancuso
authors.forename: François
authors.initials: F
authors.lastname: Bouteau
mesh_terms: D017360:Arabidopsis / Q000166:cytology* / Q000187:drug effects / Q000201:enzymology*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D020169:Caspases / Q000378:metabolism*; D004789:Enzyme Activation / Q000187:drug effects; D010126:Ozone / Q000494:pharmacology*; D015221:Potassium Channels / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D026082:Singlet Oxygen / Q000494:pharmacology; D013997:Time Factors
chemical_list: D029681:Arabidopsis Proteins; D015221:Potassium Channels; D017382:Reactive Oxygen Species; D026082:Singlet Oxygen; D010126:Ozone; D020169:Caspases
keywords: Arabidopsis thaliana; caspase; ion channel; ozone; programmed cell death; reactive oxygen species; singlet oxygen