title: New mutation L324M in the ABL1 kinase domain: does it confer high resistance to second-generation inhibitors?
authors.affiliation: Departamento de Genética, Instituto de Investigaciones Hematológicas (IIHEMA), Academia Nacional de Medicina de Buenos Aires (ANM) , Buenos Aires , Argentina.
authors.forename: María Fernanda
authors.initials: MF
authors.lastname: Noriega
authors.forename: Cristian Alberto
authors.initials: CA
authors.lastname: Ferri
authors.forename: Gustavo
authors.initials: G
authors.lastname: Icardi
authors.forename: Eduardo
authors.initials: E
authors.lastname: Bullorsky
authors.forename: Jorge
authors.initials: J
authors.lastname: Korin
authors.forename: Irene
authors.initials: I
authors.lastname: Larripa
mesh_terms: D000328:Adult; D019943:Amino Acid Substitution; D003062:Codon; D019008:Drug Resistance, Neoplasm / Q000235:genetics; D016044:Fusion Proteins, bcr-abl / Q000737:chemistry / Q000235:genetics*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy / Q000235:genetics; D008297:Male; D009154:Mutation; D054730:Protein Interaction Domains and Motifs / Q000235:genetics*; D047428:Protein Kinase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D003062:Codon; D047428:Protein Kinase Inhibitors; D016044:Fusion Proteins, bcr-abl