title: Detection of polybrominated diphenyl ethers in culture media and protein sources used for human in vitro fertilization.
abstract: The concentrations of 10 polybrominated diphenyl ethers (PBDEs) in commercial culture media and protein sources (PSs) for in vitro fertilization (IVF) of human ova were investigated. Samples of 15 IVF media (IVFM), nine sperm preparation media (SPM), and six PSs were analyzed. PBDEs were detected in 10 IVFM, seven SPM, and all PS samples in ranges of 0.6-35, 0.9-31, and 7.5-385pgg(-1), respectively. A dominant PBDE congener BDE-47 was detected in the PS and PS-supplemented samples. Our findings suggested that PS supplementation was the potential cause of PBDE-contamination of IVFM and SPM.
authors.affiliation: Department of Food, Drugs and Environment, Osaka Prefectural Institute of Public Health, 1-3-69 Nakamichi, Higashinari-ku, Osaka 537-0025, Japan.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Akutsu
authors.forename: Satoshi
authors.initials: S
authors.lastname: Takatori
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakazawa
authors.forename: Tsunehisa
authors.initials: T
authors.lastname: Makino
mesh_terms: D003470:Culture Media / Q000032:analysis*; D005307:Fertilization in Vitro; D055768:Halogenated Diphenyl Ethers / Q000032:analysis*; D006801:Humans; D010949:Plasma / Q000737:chemistry; D011075:Polybrominated Biphenyls / Q000032:analysis; D011506:Proteins
chemical_list: C477694:2,2',4,4',5-brominated diphenyl ether; D003470:Culture Media; D055768:Halogenated Diphenyl Ethers; D011075:Polybrominated Biphenyls; D011506:Proteins; C517828:hexabrominated diphenyl ether 153; C517827:pentabrominated diphenyl ether 100; C511295:2,2',4,4'-tetrabromodiphenyl ether