title: Role of human papilloma virus infection and oral-genital contact in oral cancer ethiopathogenesis.
abstract: Head and neck squamous cell carcinoma and especially oropharyngeal squamous cell carcinoma is a very significant cause of morbidity and mortality. The majors risk factors of these tumors are tobacco smoking, chewing and alcohol consumption. But there is a group, non-drinking and non-smoking, patients with oropharyngeal squamous cell carcinoma. In these patients may be oral-genital contact and human papillomavirus infection the major risk factor for oral carcinogenesis. Aim of this review is to point out this fact in correlation with clinical studies and clinical conclusion for medical practice (Fig. 1, Ref. 32).
authors.affiliation: Department of Stomatology and Maxillofocal Surgery, Comenius University and St. Elizabeth Hospital. peter.stanko@ousa.sk
authors.forename: P
authors.initials: P
authors.lastname: Stanko
authors.forename: P
authors.initials: P
authors.lastname: Kruzliak
authors.forename: P
authors.initials: P
authors.lastname: Labas
mesh_terms: D006801:Humans; D009062:Mouth Neoplasms / Q000209:etiology / Q000821:virology*; D030361:Papillomavirus Infections / Q000150:complications* / Q000209:etiology; D012307:Risk Factors; D012725:Sexual Behavior
keywords: head and neck squamous cell carcinoma, oropharyngeal squamous cell carcinoma, human papilloma virus infection, oral-genital contact, ethiopathogenesis.