title: Effects of deltamethrin on biometric parameters and liver biomarkers in common carp (Cyprinus carpio L.).
abstract: The present study is aimed to evaluate the effect of sublethal exposure to the pyrethroid pesticide deltamethrin, according to biometric parameters and important liver biomarkers in the common carp (Cyprinus carpio). Fish were exposed for 4, 15 and 30 days to deltamethrin mixed to the aquaria water at the concentrations of 0.08, 0.4 and 0.8μg/L. The exposure did not affect fish biometric parameters. Glutathione-S-transferase (GST) activity in liver (hepatopancreas) increased in fish exposed to the high concentration of pesticide only after 30 days when compared to controls. A significant increase of malondialdehyde (MDA) content (79.4% and 90.2% of control) was remarked after 15 and 30 days of exposure to the highest concentration of pesticide. Catalase activities (CAT) went up after 4 days of was to the concentration of 0.4μg/L and 0.8μg/L and at 15 days of exposure to 0.4μg/L. The most significant change of glutathione reductase (GR) activity was recorded at the fourth day, when GR activity was significantly increased after exposure to the concentrations of 0.4μg/L and 0.8μg/L of deltamethrin.
authors.affiliation: Hydrology and Plonctology Group, Faculty of Sciences of Bizerte, University Carthage, Zarzouna, Tunisia. Electronic address: cherif.bfsa@yahoo.fr.
authors.forename: C
authors.initials: C
authors.lastname: Ensibi
authors.affiliation: Toxicology Unit, Faculty of Veterinary Medicine (UEX), Caceres, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Pérez-López
authors.affiliation: Toxicology Unit, Faculty of Veterinary Medicine (UEX), Caceres, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Soler Rodríguez
authors.affiliation: Toxicology Unit, Faculty of Veterinary Medicine (UEX), Caceres, Spain.
authors.forename: M P
authors.initials: MP
authors.lastname: Míguez-Santiyán
authors.affiliation: Hydrology and Plonctology Group, Faculty of Sciences of Bizerte, University Carthage, Zarzouna, Tunisia.
authors.forename: M N Daly
authors.initials: MND
authors.lastname: Yahya
authors.affiliation: Toxicology Unit, Faculty of Veterinary Medicine (UEX), Caceres, Spain. Electronic address: davidhm@unex.es.
authors.forename: D
authors.initials: D
authors.lastname: Hernández-Moreno
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D001699:Biometry; D001835:Body Weight / Q000187:drug effects*; D002347:Carps / Q000033:anatomy & histology / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D029941:Fish Proteins / Q000378:metabolism; D005980:Glutathione Reductase / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008315:Malondialdehyde / Q000378:metabolism; D009570:Nitriles / Q000633:toxicity*; D018384:Oxidative Stress / Q000187:drug effects; D010575:Pesticides / Q000633:toxicity*; D011722:Pyrethrins / Q000633:toxicity*; D013997:Time Factors; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D015415:Biomarkers; D029941:Fish Proteins; D009570:Nitriles; D010575:Pesticides; D011722:Pyrethrins; D014874:Water Pollutants, Chemical; C017180:decamethrin; D008315:Malondialdehyde; D002374:Catalase; D005980:Glutathione Reductase
keywords: Catalase; Cyprinus carpio; Deltamethrin; Glutathione reductase; Glutathione-S-transferase; MDA