title: Long-term outcomes of endoscopic sinus surgery for chronic rhinosinusitis with and without nasal polyps.
abstract: Chronic rhinosinusitis (CRS) significantly affects patient quality of life. Medical and surgical treatments aim to clinically manage the condition.
  
  
  OBJECTIVE
  To assess the long-term quality of life and clinical management of CRS in patients submitted to endoscopic sinus surgery.
  
  
  METHODS
  This prospective cross-sectional cohort study enrolled 38 patients and looked into the follow-up data of subjects diagnosed with CRS before surgery, three months after surgery, and at least two years after surgery. The Sinonasal Outcome Test 22 (SNOT-22) was used to assess response to treatment and long-term clinical management of the disease.
  
  
  RESULTS
  Significant improvements in the SNOT-22 scores were seen between the preoperative (61.3) and postoperative assessments with three (16.9) and 24 (32.3) months. No statistically significant differences were seen when patients with polyps were compared to polyp-free subjects. Few patients were controlled in both groups, and 7.89% of the subjects had revision surgery during the study.
  
  
  CONCLUSIONS
  Endoscopic sinus surgery significantly improved the quality of life of patients with chronic rhinosinusitis. Clinical control of the condition was acceptable, with few patients requiring re-operation within two years of the first surgery.
authors.affiliation: UNIFESP-EPM, Brazil.
authors.forename: Juliana Gama
authors.initials: JG
authors.lastname: Mascarenhas
authors.forename: Viviane Maria Guerreiro
authors.initials: VM
authors.lastname: da Fonseca
authors.forename: Vitor Guo
authors.initials: VG
authors.lastname: Chen
authors.forename: Caroline Harumi
authors.initials: CH
authors.lastname: Itamoto
authors.forename: Camila Atallah Pontes da
authors.initials: CA
authors.lastname: Silva
authors.forename: Luis Carlos
authors.initials: LC
authors.lastname: Gregório
authors.forename: Eduardo Macoto
authors.initials: EM
authors.lastname: Kosugi
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000601:surgery*; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D011446:Prospective Studies; D011788:Quality of Life; D012220:Rhinitis / Q000601:surgery*; D012852:Sinusitis / Q000601:surgery*; D016896:Treatment Outcome