title: A case of primary mediastinal Ewing's sarcoma / primitive neuroectodermal tumor presenting with initial compression of superior vena cava.
abstract: Ewing's sarcomas and peripheral primitive neuroectodermal tumors (ES/PNETs) are high grade malignant neoplasms. These malignancies are characterized by a chromosome 22 rearrangement, arise from bone or soft tissue, predominantly affect children and young adults, and are grouped in the Ewing family of tumors. Multimodality treatment programs are the treatment of choice. Primary localization of ES/PNET in the mediastinum is extremely rare. We describe a case of ES/PNET presenting as a mediastinal mass with tracheal compression and initial signs of superior vena cava in a 66-year-old woman.
authors.affiliation: Radiation Oncology Unit, University of Turin, S. Luigi Hospital, Orbassano, Italy.
authors.forename: Alessia
authors.initials: A
authors.lastname: Reali
authors.forename: Gianluca
authors.initials: G
authors.lastname: Mortellaro
authors.forename: Simona
authors.initials: S
authors.lastname: Allis
authors.forename: Edoardo
authors.initials: E
authors.lastname: Trevisiol
authors.forename: Silvia Maria
authors.initials: SM
authors.lastname: Anglesio
authors.forename: Sara
authors.initials: S
authors.lastname: Bartoncini
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Ruo Redda
keywords: Ewing's sarcoma; extraosseous; extraskeletal; peripheral primitive neuroectodermal tumor