title: Effects and mechanisms of mechanical stress on secondary fracture healing.
abstract: Fracture healing is an extremely complex biological reconstruction process, affected by age, hormones, blood supply, degree of injury, mechanical load and many other factors, among which, mechanical stimuli is one of the most important. Bone tissue has a good adaptability to mechanical stress, as biomechanical studies have shown that the local mechanical environment of the fracture site plays a regulatory role in the process of fracture healing. The present article reviews the mechanical mechanisms and effects of mechanical stress on fracture healing.
authors.affiliation: Department of Orthopedic Surgery, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 200233, China. yuxg1979@yeah.net
authors.forename: Xingang
authors.initials: X
authors.lastname: Yu
authors.forename: Yanjie
authors.initials: Y
authors.lastname: Guo
authors.forename: Qinglin
authors.initials: Q
authors.lastname: Kang
authors.forename: Congfeng
authors.initials: C
authors.lastname: Luo
mesh_terms: D017102:Fracture Healing; D006801:Humans; D013314:Stress, Mechanical