title: Timing of motor milestones achievement and development of overweight in childhood: a study within the Danish National Birth Cohort.
abstract: BACKGROUND
  Overweight may hinder achievement of gross motor milestones and delayed achievement of milestones may increase the risk of later overweight for reasons involving physical activity and the building of lean body mass.
  
  
  OBJECTIVE
  To investigate whether increased birth weight and body mass index (BMI) at 5 months is associated with the achievement of the ability to sit up and walk and whether delayed achievement of these milestones is associated with overweight at age 7 years.
  
  
  METHODS
  We used data from the Danish National Birth Cohort on 25,148 children born between 1998 and 2003. Follow-up took place from 2003 to 2010. Mean age at follow-up was 7.04 years. We used logistic and linear regression analyses.
  
  
  RESULTS
  Birth weight and BMI at 5 months were marginally associated with earlier achievement of the ability to sit up and walk (regression coefficients between -0.027 months; [CI -0.042; -0.013] and -0.092 months [CI -0.118; -0.066]). Age in months of sitting and walking were not associated with overweight at age 7 years (ORs between 0.97 [CI 0.95-1.00] and 1.00 [CI 0.96-1.04]). Later achievement of sitting and walking predicted lower BMI at age 7 years (ln-BMI -z-scores between -0.023 [CI -0.029; -0.017] and -0.005 [CI -0.015; 0.005)).
  
  
  CONCLUSIONS
  All observed associations were of negligible magnitude and we conclude that birth weight or BMI at age 5 months and motor milestones appear largely independent of each other and that timing of achievement of motor milestones seems not to be associated with later overweight or increased BMI.
authors.affiliation: Section of Social Medicine, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
authors.forename: C
authors.initials: C
authors.lastname: Schmidt Morgen
authors.forename: A M N
authors.initials: AM
authors.lastname: Andersen
authors.forename: P
authors.initials: P
authors.lastname: Due
authors.forename: S B
authors.initials: SB
authors.lastname: Neelon
authors.forename: M
authors.initials: M
authors.lastname: Gamborg
authors.forename: T I A
authors.initials: TI
authors.lastname: Sørensen
mesh_terms: D001724:Birth Weight; D015992:Body Mass Index; D001835:Body Weight; D002648:Child; D002657:Child Development; D002675:Child, Preschool; D015331:Cohort Studies; D003718:Denmark / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016015:Logistic Models; D008297:Male; D063766:Pediatric Obesity / Q000453:epidemiology* / Q000517:prevention & control; D011237:Predictive Value of Tests; D011597:Psychomotor Performance; D012016:Reference Values; D012307:Risk Factors; D013997:Time Factors
keywords: Child; cohort study; motor milestone; obesity