title: The effect of topical cyclosporine 0.05% on dry eye after cataract surgery.
abstract: OBJECTIVE
  To evaluate the effectiveness of cyclosporine 0.05% for dry eye after cataract surgery.
  
  
  METHODS
  Thirty-two newly diagnosed patients with dry eye syndrome 1 week after cataract surgery received a twice-daily treatment of cyclosporine 0.05% for one eye and normal saline 0.9% for the other. Disease severity was measured at 2 weeks, 1 month, 2 months, and 3 months by Schirmer test I (ST-I), tear film break-up time (tBUT), corneal temperature and dry eye symptom questionnaire (Ocular Surface Disease Index).
  
  
  RESULTS
  Both groups increased in ST-I and tBUT over time. ST-I in the cyclosporine 0.05% group showed a significant increase at 3 months and tBUT in the cyclosporine 0.05% group showed an increase at 2 and 3 months. The dry eye symptom score was significantly reduced in the cyclosporine 0.05% group.
  
  
  CONCLUSIONS
  Cyclosporine 0.05% can also be an effective treatment for dry eye after cataract surgery.
authors.affiliation: Department of Ophthalmology, Yeouido St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Yeon Woong
authors.initials: YW
authors.lastname: Chung
authors.forename: Tae Hoon
authors.initials: TH
authors.lastname: Oh
authors.forename: Sung Kun
authors.initials: SK
authors.lastname: Chung
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction; D016572:Cyclosporine / Q000008:administration & dosage*; D015352:Dry Eye Syndromes / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D011183:Postoperative Complications / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D009883:Ophthalmic Solutions; D016572:Cyclosporine
keywords: Cataract surgery; Cyclosporine; Dry eye syndromes