title: Complete lysosomal disruption: a route to necrosis, not to the inflammasome.
authors.affiliation: Division of Gastroenterology and Hepatology; College of Medicine; Mayo Clinic; Rochester, MN, USA.
authors.forename: Maria Eugenia
authors.initials: ME
authors.lastname: Guicciardi
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Gores
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism*; D008247:Lysosomes / Q000378:metabolism*; D009336:Necrosis / Q000378:metabolism*
chemical_list: D002352:Carrier Proteins
keywords: cathepsins; inflammasome; lysosomes; pro-inflammatory cytokines; pyroptosis