title: Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections.
abstract: Treatment of Scedosporium apiospermum central nervous system (CNS) infection typically consists of an azole in combination with surgical debridement. This approach requires prolonged treatment and carries a high associated mortality. We present two cases of the successful treatment of S. apiospermum CNS infections with the combination of voriconazole and terbinafine.
authors.affiliation: Division of Infectious Diseases, University of Colorado Denver, 12700 E. 19th Avenue, Mail Stop B168, Aurora, CO 80045, USA.
authors.forename: Andrés F
authors.initials: AF
authors.lastname: Henao-Martínez
authors.forename: José R
authors.initials: JR
authors.lastname: Castillo-Mancilla
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Barron
authors.forename: Aran Cunningham
authors.initials: AC
authors.lastname: Nichol