title: Clinical results after nonsurgical therapy in aggressive and chronic periodontitis.
abstract: OBJECTIVE
  This study aims to analyze factors influencing treatment results in aggressive (AgP) and chronic (ChP) periodontitis.
  
  
  METHODS
  ChP [probing pocket depth (PPD) ≥ 3.5 mm, attachment loss ≥ 5 mm at >30 % of sites; age > 35 years] and AgP (clinically healthy; PPD ≥ 3.5 mm at >30 % of sites, radiographic bone loss ≥ 50 % at 2 teeth; age ≤ 35 years) were examined prior and 3 months after nonsurgical therapy according to the full-mouth disinfection concept. Adjunctive systemic antibiotics were used if Aggregatibacter actinomycetemcomitans had been detected at baseline.
  
  
  RESULTS
  In 31 ChP (12 female, 10 smokers; 4,808 sites) and 28 AgP (16 female, 9 smokers; 4,769 sites), overall mean PPD reductions were less favorable in AgP (0.9 ± 0.5 mm) than in ChP (1.3 ± 0.4 mm; p = 0.033). PPD reductions and relative vertical probing attachment level gain were more favorable at sites with initial PPD ≥ 6 mm, bleeding on probing, and for adjunctive systemic antibiotics. Furthermore, PPD reductions were more favorable for increased baseline tooth mobility and maxillary teeth, whereas AgP, female sex, and multirooted teeth were associated with less favorable PPD reduction.
  
  
  CONCLUSIONS
  Regarding PPD reduction, AgP responded less favorably to nonsurgical treatment than ChP.
authors.affiliation: Department of Periodontology, Centre for Dental, Oral, and Maxillofacial Medicine (Carolinum), Johann Wolfgang Goethe-University Frankfurt/Main, Theodor-Stern-Kai 7, 60596, Frankfurt, Germany.
authors.forename: Susanne
authors.initials: S
authors.lastname: Scharf
authors.forename: Martin
authors.initials: M
authors.lastname: Wohlfeil
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Siegelin
authors.forename: Beate
authors.initials: B
authors.lastname: Schacher
authors.forename: Bettina
authors.initials: B
authors.lastname: Dannewitz
authors.forename: Peter
authors.initials: P
authors.lastname: Eickholz
mesh_terms: D000328:Adult; D002908:Chronic Disease; D006801:Humans; D010518:Periodontitis / Q000628:therapy*