title: Dramatic regression of persistent tunica vasculosa lentis associated with retinopathy of prematurity following treatment with intravitreal bevacizumab.
abstract: The authors describe a preterm infant who developed advanced retinopathy of prematurity bilaterally with a prominent tunica vasculosa lentis. Treatment with intravitreal bevacizumab resulted in regression of the tunica vasculosa lentis and posterior manifestations of the retinopathy of prematurity. RetCam imaging (Clarity Medical Systems, Pleasanton, CA) of the anterior segment was used to document the dramatic tunica vasculosa lentis resolution.
authors.affiliation: Department of Ophthalmology, New England Eye Center, Tufts Medical Center, Boston, MA 02111, USA.
authors.forename: Darin R
authors.initials: DR
authors.lastname: Goldman
authors.forename: Caroline R
authors.initials: CR
authors.lastname: Baumal
mesh_terms: D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D000068258:Bevacizumab; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007905:Lens Diseases / Q000150:complications* / Q000188:drug therapy*; D007908:Lens, Crystalline / Q000002:abnormalities*; D008297:Male; D012178:Retinopathy of Prematurity / Q000150:complications* / Q000188:drug therapy*
chemical_list: D020533:Angiogenesis Inhibitors; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab