title: Intra-operative radiological margins assessment in conservative treatment for non-palpable DCIS: correlation to pathological examination and re-excision rate.
abstract: What constitutes an adequate surgical margin in partial mastectomy is still controversial: intra-operative specimen radiogram is commonly used during partial mastectomy for nonpalpable lesions in order verify the adequacy of the resection but what margin is to be considered "adequate" is still debatable. An intraoperative specimen mammogram was performed during all consecutive conservative resections for nonpalpable DCIS and a 15-mm radiological margin was considered "adequate". Margins were pathologically assessed and classified as "negative", "close" or "positive" and the rate of margin involvement constitued the main outcome of the study. Among 272 conservative interventions, 80.51% had negative margins at final pathology, 3.31% had close margins and 16.18% had positive margins. An intraoperative "adequate" margin of 15 mm as defined on intraoperative specimen mammogram granted a high rate of histologically negative margin at primary surgery; this finding was paralleled by confirmation of the treatment as conservative in 95% of cases.
authors.affiliation: Breast Unit, Morgagni-Pierantoni Hospital, Forlì, Italy.
authors.forename: Federico
authors.initials: F
authors.lastname: Buggi
authors.forename: Matteo
authors.initials: M
authors.lastname: Mingozzi
authors.forename: Annalisa
authors.initials: A
authors.lastname: Curcio
authors.forename: Camilla
authors.initials: C
authors.lastname: Rossi
authors.forename: Oriana
authors.initials: O
authors.lastname: Nanni
authors.forename: Lucia
authors.initials: L
authors.lastname: Bedei
authors.forename: Paola A
authors.initials: PA
authors.lastname: Sanna
authors.forename: Salvatore
authors.initials: S
authors.lastname: Veltri
authors.forename: Secondo
authors.initials: S
authors.lastname: Folli