title: Spatial analyses of typhoid fever in Jiangsu province, People's Republic of China.
abstract: An analysis of the geographical distribution of typhoid incidence rates, based on various statistical approaches such as trend surface, spatial autocorrelation, spatial correlation and spatial regression, was carried out at the county level in Jiangsu province, People's Republic of China. Temperature, moisture content, proximity to water bodies and the normalized difference vegetation index in the autumn were the four underlying factors found to contribute the most to the development of the epidemic. Typhoid infection was most severe in the south-eastern region of Jiangsu and a significant hotspot with high positive autocorrelation was detected in Taicang county in the south-east of the province. To improve the typhoid situation, intervention efforts should be concentrated in the south-eastern region of the province, targeting the hotspot and include reduction of lake pollution.
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China.
authors.forename: Yue-Jia
authors.initials: YJ
authors.lastname: Cheng
authors.forename: Fen-Yang
authors.initials: FY
authors.lastname: Tang
authors.forename: Chang-Jun
authors.initials: CJ
authors.lastname: Bao
authors.forename: Ye-Fei
authors.initials: YF
authors.lastname: Zhu
authors.forename: Qi
authors.initials: Q
authors.lastname: Liang
authors.forename: Jian-Li
authors.initials: JL
authors.lastname: Hu
authors.forename: Wen-Dong
authors.initials: WD
authors.lastname: Liu
authors.forename: Ying
authors.initials: Y
authors.lastname: Wu
authors.forename: Kathleen H
authors.initials: KH
authors.lastname: Reilly
authors.forename: Tong-Qian
authors.initials: TQ
authors.lastname: Shen
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhao
authors.forename: Zhi-Hang
authors.initials: ZH
authors.lastname: Peng
authors.forename: Rong-Bin
authors.initials: RB
authors.lastname: Yu
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
authors.forename: Hong-Bing
authors.initials: HB
authors.lastname: Shen
authors.forename: Feng
authors.initials: F
authors.lastname: Chen
mesh_terms: D040362:Geographic Information Systems; D006801:Humans; D015994:Incidence; D012621:Seasons; D012720:Severity of Illness Index; D062206:Spatial Analysis; D013624:Taiwan / Q000453:epidemiology; D013696:Temperature; D014435:Typhoid Fever / Q000453:epidemiology*; D014867:Water
chemical_list: D014867:Water