title: Development of ratiometric near-infrared fluorescent probes using analyte-specific cleavage of carbamate.
abstract: We report a facile method to design NIR ratiometric fluorescent probes in terms of analyte-induced carbamate cleavage. Two examples, CyNB and CyNN3, exhibit a significant analyte-triggered response with ratiometric fluorescence change in the NIR range and dual-emission ratiometry in living cells.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, PR China.
authors.forename: Dongjian
authors.initials: D
authors.lastname: Zhu
authors.forename: Guoping
authors.initials: G
authors.lastname: Li
authors.forename: Lin
authors.initials: L
authors.lastname: Xue
authors.forename: Hua
authors.initials: H
authors.lastname: Jiang
mesh_terms: D002219:Carbamates / Q000737:chemistry*; D015195:Drug Design; D005456:Fluorescent Dyes / Q000737:chemistry*; D007259:Infrared Rays
chemical_list: D002219:Carbamates; D005456:Fluorescent Dyes