title: Antioxidant properties of aqueous extracts of unripe Musa paradisiaca on sodium nitroprusside induced lipid peroxidation in rat pancreas in vitro.
abstract: OBJECTIVE
  To evaluate and compare antioxidant activities of the aqueous extracts of unripe plantain (Musa paradisiaca), assess their inhibitory action on sodium nitroprusside induced lipid peroxidation in rat pancreas in vitro and to characterize the main phenolic constituents of the plantain products using gas chromatography analysis.
  
  
  METHODS
  Aqueous extracts of plantain products (raw, elastic pastry, roasted and boiled) flour of 0.1 g/mL (each) were used to determine their total phenol, total flavonoid, 1,1 diphenyl-2 picrylhydrazyl (DPPH) and hydroxyl (OH) radical scavenging ability. The inhibitory effect of the extracts on sodium nitroprusside induced lipid peroxidation was also determined.
  
  
  RESULTS
  The results revealed that all the aqueous extracts showed antioxidant activity. The boiled flour had highest DPPH and OH radical scavenging ability while raw flour had the highest Fe(2+) chelating ability, sodium nitroprusside inhibitory effect and vitamin C content. The antioxidant results showed that elastic pastry had the highest total phenol and total flavonoid content. Characterization of the unripe plantain products for polyphenol contents using gas chromatography showed varied quantity of apigenin, myricetin, luteolin, capsaicin, isorhaemnetin, caffeic acid, kampferol, quercetin, p-hydroxybenzoic acid, shogaol, glycitein and gingerol per product on the spectra.
  
  
  CONCLUSIONS
  Considering the antioxidant activities and ability to inhibit lipid peroxidation of unripe plantain, this could justify their traditional use in the management/prevention of diseases related to stress.
authors.affiliation: Department of Biochemistry, Adekunle Ajasin University, P.M.B 01 Akungba-Akoko. Ondo State, Nigeria.
authors.forename: Sidiqat Adamson
authors.initials: SA
authors.lastname: Shodehinde
authors.forename: Ganiyu
authors.initials: G
authors.lastname: Oboh
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002849:Chromatography, Gas; D003296:Cooking; D015227:Lipid Peroxidation / Q000187:drug effects*; D028521:Musa / Q000737:chemistry*; D009599:Nitroprusside / Q000737:chemistry; D010179:Pancreas / Q000187:drug effects* / Q000378:metabolism; D010636:Phenols / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats
chemical_list: D000975:Antioxidants; D010636:Phenols; D010936:Plant Extracts; D009599:Nitroprusside
keywords: Antioxidants; Lipid peroxidation; Musa paradisiacal; Polyphenols; Sodium nitroprusside