title: Elucidating the fungal stress response by proteomics.
abstract: Fungal species need to cope with stress, both in the natural environment and during interaction of human- or plant pathogenic fungi with their host. Many regulatory circuits governing the fungal stress response have already been discovered. However, there are still large gaps in the knowledge concerning the changes of the proteome during adaptation to environmental stress conditions. With the application of proteomic methods, particularly 2D-gel and gel-free, LC/MS-based methods, first insights into the composition and dynamic changes of the fungal stress proteome could be obtained. Here, we review the recent proteome data generated for filamentous fungi and yeasts. This article is part of a Special Issue entitled: Trends in Microbial Proteomics.
authors.affiliation: Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (HKI), Beutenbergstrasse 11a, 07745 Jena, Germany; Friedrich Schiller University, Institute of Microbiology, Philosophenweg 12, 07743 Jena, Germany.
authors.forename: Kristin
authors.initials: K
authors.lastname: Kroll
authors.affiliation: Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (HKI), Beutenbergstrasse 11a, 07745 Jena, Germany; Friedrich Schiller University, Institute of Microbiology, Philosophenweg 12, 07743 Jena, Germany; Integrated Research and Treatment Center, Center for Sepsis Control and Care Jena, University Hospital (CSCC), 07747 Jena, Germany.
authors.forename: Vera
authors.initials: V
authors.lastname: Pähtz
authors.affiliation: Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (HKI), Beutenbergstrasse 11a, 07745 Jena, Germany; Friedrich Schiller University, Institute of Microbiology, Philosophenweg 12, 07743 Jena, Germany; Integrated Research and Treatment Center, Center for Sepsis Control and Care Jena, University Hospital (CSCC), 07747 Jena, Germany. Electronic address: olaf.kniemeyer@hki-jena.de.
authors.forename: Olaf
authors.initials: O
authors.lastname: Kniemeyer
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D005658:Fungi / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D020543:Proteome / Q000235:genetics / Q000378:metabolism*; D040901:Proteomics; D013312:Stress, Physiological / Q000502:physiology*
chemical_list: D001426:Bacterial Proteins; D020543:Proteome
keywords: Fungi; Hypoxia; Oxidative stress; Proteome; Stress response