title: Bacteria of the genus Dyella can chronically colonise the airways of patients with cystic fibrosis and elicit a pronounced antibody response.
abstract: A patient with cystic fibrosis became chronically colonised with an unusual non-fermenting Gram-negative rod that could be cultured on Burkholderia cepacia selective agar. Phenotypic characterisation by VITEK-2 suggested identification as Elizabethkingia meningoseptica, however 16S rRNA gene sequencing revealed it belonged to a putative novel species of genus Dyella. Thirty months after the initial detection, the patient produced a high level of precipitating antibodies against the bacterium.
authors.affiliation: Department of Clinical Microbiology, Aarhus University Hospital, DK-8200 Aarhus, Denmark.
authors.forename: Liv M
authors.initials: LM
authors.lastname: Duus
authors.forename: Niels
authors.initials: N
authors.lastname: Høiby
authors.forename: Mikala
authors.initials: M
authors.lastname: Wang
authors.forename: Oluf
authors.initials: O
authors.lastname: Schiøtz
authors.forename: Niels
authors.initials: N
authors.lastname: Nørskov-Lauritsen
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood; D015373:Bacterial Typing Techniques; D002353:Carrier State / Q000276:immunology / Q000382:microbiology*; D016000:Cluster Analysis; D003550:Cystic Fibrosis / Q000150:complications*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D016905:Gram-Negative Bacterial Infections / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D044166:Xanthomonadaceae / Q000145:classification / Q000254:growth & development / Q000276:immunology* / Q000302:isolation & purification
chemical_list: D000907:Antibodies, Bacterial; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S