title: Adenomatoid odontogenic tumor: a case report with immunohistological profile.
abstract: The adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin, composed of odontogenic epithelium and characterized by slow but progressive growth. We report a rare case of AOT in an 18-year-old, who presented with a palpable bony-hard swelling in the anterior maxillary region. The tumor was radiographically well-defined, and exhibited unilocular radiolucency. Histologically, the appearance was of solid nodules of cuboid or columnar cells of odontogenic epithelium, forming typical nests or duct-like structures. Immunohistochemistry was positive for cytokeratins (CK) CK5/6, CK17, CK19 and negative for KI-67. The results were consistent with a diagnosis of AOT.
  
  
  CONCLUSIONS
  A case of AOT is presented, emphasizing on the importance of recognizing neoplasms arising in odontogenic tissues. Recurrences seldom occur, and surgical cure is recommended.
authors.affiliation: Ospedale San Martino, Largo R Benzi, 10 Genova Italy. f.angiero@teos.it.
authors.forename: Francesca
authors.initials: F
authors.lastname: Angiero
authors.forename: Rolando
authors.initials: R
authors.lastname: Crippa
mesh_terms: D000293:Adolescent; D000564:Ameloblastoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D019394:Ki-67 Antigen / Q000032:analysis; D008441:Maxillary Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D009808:Odontogenic Tumors / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D011859:Radiography
chemical_list: D019394:Ki-67 Antigen; D007633:Keratins
keywords: Adenomatoid tumor; jaws tumor; odontogenic tumor