title: Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil.
abstract: BACKGROUND
  Amphotericin B (AMB) is an antifungal agent used extensively in clinical medicine, yet resistance remains low. This study aims to evaluate the susceptibility of Candida spp. against AMB.
  
  
  METHODS
  For broth microdilution susceptibility testing, 77 strains of Candida spp. were selected (32 C. albicans, 33 C. tropicalis, and 12 C. parapsilosis). The strains were considered susceptible when they exhibited MIC≤1.0µg/ml.
  
  
  RESULTS
  None of the strains showed an MIC greater than 0.25µg/ml.
  
  
  CONCLUSIONS
  Further works are necessary, with a higher number of strains, to assess the validity of the results used in this study.
authors.affiliation: Laboratório de Bioprospecção e Experimentação em Leveduras, Departamento de Análises Clinicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Ceará, Fortaleza,CE.
authors.forename: Cecília Rocha da
authors.initials: CR
authors.lastname: Silva
authors.forename: Hemerson Iury Ferreira
authors.initials: HI
authors.lastname: Magalhães
authors.forename: Manoel Odorico de
authors.initials: MO
authors.lastname: Moraes
authors.forename: Hélio Vitoriano
authors.initials: HV
authors.lastname: Nobre Júnior
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000145:classification / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B