title: The valuation of the EQ-5D in Portugal.
abstract: OBJECTIVE
  The EQ-5D is a preference-based measure widely used in cost-utility analysis (CUA). Several countries have conducted surveys to derive value sets, but this was not the case for Portugal. The purpose of this study was to estimate a value set for the EQ-5D for Portugal using the time trade-off (TTO).
  
  
  METHODS
  A representative sample of the Portuguese general population (n = 450) stratified by age and gender valued 24 health states. Face-to-face interviews were conducted by trained interviewers. Each respondent ranked and valued seven health states using the TTO. Several models were estimated at both the individual and aggregated levels to predict health state valuations. Alternative functional forms were considered to account for the skewed distribution of these valuations.
  
  
  RESULTS
  The models were analyzed in terms of their coefficients, overall fit and the ability for predicting the TTO values. Random effects models were estimated using generalized least squares and were robust across model specification. The results are generally consistent with other value sets.
  
  
  CONCLUSIONS
  This research provides the Portuguese EQ-5D value set based on the preferences of the Portuguese general population as measured by the TTO. This value set is recommended for use in CUA conducted in Portugal.
authors.affiliation: School of Management, Hospitality and Tourism, University of the Algarve, Faro, Portugal, Lnferrei@ualg.pt.
authors.forename: Lara N
authors.initials: LN
authors.lastname: Ferreira
authors.forename: Pedro L
authors.initials: PL
authors.lastname: Ferreira
authors.forename: Luis N
authors.initials: LN
authors.lastname: Pereira
authors.forename: Mark
authors.initials: M
authors.lastname: Oppe
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006304:Health Status; D006306:Health Surveys / Q000379:methods* / Q000592:standards; D006801:Humans; D007407:Interviews as Topic; D016018:Least-Squares Analysis; D008297:Male; D008875:Middle Aged; D011174:Portugal; D011788:Quality of Life; D019057:Quality-Adjusted Life Years; D011795:Surveys and Questionnaires; D055815:Young Adult