title: Review of antimicrobial therapy of selected bacterial diseases in broiler chickens in Canada.
abstract: This paper reviews common therapeutic applications of antimicrobials in broiler chicken production in relation to Canadian guidelines, surveillance data, and emerging public health concerns about antimicrobial use (AMU). Escherichia coli, Clostridium perfringens, and Staphylococcus spp., were reviewed because of their animal health and economic significance. Enterococcus cecorum and Salmonella were included because of their importance in antimicrobial resistance (AMR) surveillance. This review identified that i) antimicrobials are available in Canada to treat infections by these agents, but may be through over the counter or extra-label use, ii) prevalence rates for these diseases are unknown, iii) antimicrobial use estimates in broilers are lacking, and iv) AMR has emerged in clinical isolates, though data are very sparse. This review highlights the need for surveillance of AMU and AMR in broiler chickens in Canada.
authors.affiliation: Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, Guelph, Ontario, Canada N1G 5B2. agnes.agunos@phac-aspc.gc.ca
authors.forename: Agnes
authors.initials: A
authors.lastname: Agunos
authors.forename: Dave
authors.initials: D
authors.lastname: Léger
authors.forename: Carolee
authors.initials: C
authors.lastname: Carson
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002170:Canada; D002645:Chickens; D024881:Drug Resistance, Bacterial; D005260:Female; D008297:Male; D011201:Poultry Diseases / Q000188:drug therapy*; D011358:Product Surveillance, Postmarketing
chemical_list: D000900:Anti-Bacterial Agents