title: Rhodium(III)-catalyzed intermolecular direct amidation of aldehyde C-H bonds with N-chloroamines at room temperature.
abstract: A Rh(III)-catalyzed direct aldehyde C-H amidation from aldehydes and N-chloroamines, prepared in situ from amines, has been developed via C-H bond activation under very mild reaction conditions. A variety of primary and secondary amines were used to afford the corresponding amides in moderate to excellent yields.
authors.affiliation: Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 555 Zu Chong Zhi Road, Shanghai 201203, P. R. China.
authors.forename: Bing
authors.initials: B
authors.lastname: Zhou
authors.forename: Juanjuan
authors.initials: J
authors.lastname: Du
authors.forename: Yaxi
authors.initials: Y
authors.lastname: Yang
authors.forename: Yuanchao
authors.initials: Y
authors.lastname: Li
mesh_terms: D000447:Aldehydes / Q000138:chemical synthesis* / Q000737:chemistry; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D002700:Chloramines / Q000737:chemistry*; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*; D013696:Temperature
chemical_list: D000447:Aldehydes; D000577:Amides; D002700:Chloramines; D012238:Rhodium