title: An isolated penile mass in a young adult turned out to be a primary marginal zone lymphoma of the penis. A case report and a review of literature.
abstract: OBJECTIVE
  to discuss the rationale of the management of penile MALT lymphoma.
  
  
  METHODS
  A 24-year-old patient presented with a painless and mobile nodule localized in the ventral part of the penis. The lesion was firstly evaluated through Doppler ultrasonography, which showed a hypoechoic and vascularized solid mass, a subsequent magnetic resonance confirmed size and position of the lesion. Subsequently the patient underwent a surgical excision of the mass, the pathological diagnosis was consistent with penile lymphoma, MALT-type. The patient underwent a consolidative immunotherapy with rituximab. Disease re-staging was performed through a MR without any detection of local or systemic recurrences.
  
  
  CONCLUSIONS
  To our knowledge, no cases of MALT lymphoma involving the penis have been reported in the literature so far. Surgical excision with organ sparing and immunotherapy with rituximab, successfully induced a complete response. Based upon this experience, we may recommend a conservative surgery associated with a systemic approach.
authors.affiliation: Urology Unit, University of Bologna, Bologna, Italy. dr.giorgio.gentile@gmail.com
authors.forename: Giorgio
authors.initials: G
authors.lastname: Gentile
authors.forename: Alessandro
authors.initials: A
authors.lastname: Broccoli
authors.forename: Eugenio
authors.initials: E
authors.lastname: Brunocilla
authors.forename: Riccardo
authors.initials: R
authors.lastname: Schiavina
authors.forename: Marco
authors.initials: M
authors.lastname: Borghesi
authors.forename: Daniele
authors.initials: D
authors.lastname: Romagnoli
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Bianchi
authors.forename: Enrico
authors.initials: E
authors.lastname: Derenzini
authors.forename: Claudio
authors.initials: C
authors.lastname: Agostinelli
authors.forename: Alessandro
authors.initials: A
authors.lastname: Franceschelli
authors.forename: Fulvio
authors.initials: F
authors.lastname: Colombo
authors.forename: Pier Luigi
authors.initials: PL
authors.lastname: Zinzani
mesh_terms: D000328:Adult; D058846:Antibodies, Monoclonal, Murine-Derived / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D008297:Male; D059351:Organ Sparing Treatments; D010412:Penile Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D010413:Penis / Q000473:pathology / Q000601:surgery; D011859:Radiography; D000069283:Rituximab; D055815:Young Adult
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents; D000069283:Rituximab
keywords: MALT lymphoma; penile tumor