title: Dual-index evaluation of character changes in Panax ginseng C. A. Mey stored in different conditions.
abstract: Panax ginseng C. A. Mey has been used as a traditional medicine and functional food in Asia for thousands of years for its improvement of human immunity and metabolism and its antitumor and antifatigue activities. This study reports the impact of storage conditions and storage period on the quality of P. ginseng. The contents of four major ginsenosides in P. ginseng and phosphorylation activities of Akt of ginseng extracts were affected by both storage conditions and storage period. In contrast, the ATP generation capacity of ginseng extracts was affected by storage conditions, but not by storage period. The results showed that the quality of P. ginseng could be well maintained at a relative humidity between 70% and 90%, and dry conditions might decrease the quality of P. ginseng. Through dual-index evaluation, the present study extended our knowledge on the changes of ginsenosides and bioactivities in P. ginseng with respect to different storage conditions and storage periods.
authors.affiliation: Department of Pharmacy, School of Medicine, Shenzhen University, Shenzhen 518060, China.
authors.forename: Chen-yang
authors.initials: CY
authors.lastname: Li
authors.forename: David Tai-wai
authors.initials: DT
authors.lastname: Lau
authors.forename: Tina Ting-xia
authors.initials: TT
authors.lastname: Dong
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.forename: Roy Chi-yan
authors.initials: RC
authors.lastname: Choi
authors.forename: Hai-qiang
authors.initials: HQ
authors.lastname: Wu
authors.forename: Li-yan
authors.initials: LY
authors.lastname: Wang
authors.forename: Rui-sha
authors.initials: RS
authors.lastname: Hong
authors.forename: Shi-he
authors.initials: SH
authors.lastname: Li
authors.forename: Xun
authors.initials: X
authors.lastname: Song
authors.forename: Tian
authors.initials: T
authors.lastname: Yu
authors.forename: Wei-wei
authors.initials: WW
authors.lastname: Su
authors.forename: Karl Wah-keung
authors.initials: KW
authors.lastname: Tsim
authors.forename: Zhen-dan
authors.initials: ZD
authors.lastname: He
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology; D002460:Cell Line; D002478:Cells, Cultured; D002681:China; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology; D063427:Food Quality; D061353:Food Storage; D036145:Ginsenosides / Q000032:analysis* / Q000494:pharmacology; D006801:Humans; D005894:Panax / Q000737:chemistry* / Q000254:growth & development; D010766:Phosphorylation / Q000187:drug effects; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D011499:Protein Processing, Post-Translational / Q000187:drug effects; D051381:Rats; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D036145:Ginsenosides; D010936:Plant Extracts