title: Room temperature and solvent-free iridium-catalyzed selective alkylation of anilines with alcohols.
abstract: A bidentate iridium NHC-phosphine complex has been developed and applied to the N-monoalkylation of aromatic amines with a wide range of primary alcohols and to the N-heterocyclization of amino alcohols. This reaction resulted in high isolated product yields, even at room temperature and under solvent-free conditions.
authors.affiliation: Department of Applied Chemistry, China Agricultural University, Beijing 100193, China.
authors.forename: Jia-Qi
authors.initials: JQ
authors.lastname: Li
authors.forename: Pher G
authors.initials: PG
authors.lastname: Andersson
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D000478:Alkylation; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D007495:Iridium / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry; D010720:Phosphines / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry; D013696:Temperature
chemical_list: D000438:Alcohols; D000588:Amines; D010720:Phosphines; C030011:carbene; D007495:Iridium; D012238:Rhodium; C044646:phosphine; D008697:Methane