title: [Spindle and epithelioid hemangio-endothelioma of the lymph node. Report of one case].
abstract: Primary vascular tumors of lymph nodes are extremely rare with the exception of AlDS-related Kaposi's sarcoma. The diagnosis of epithelioid hemangio-endothelioma (EH) is difficult to make without ancillary studies, since it is devoid of morphological features indicating its vascular nature and it may be overlooked when it appears as a primary tumor of lymph nodes. Spindle and epithelioid hemangio-endothelioma (SEH) is considered to be a variant of EH, which has been reported to occur exclusively in lymph nodes and the spleen. We report a 70-year-old male with chronic lymphocytic leukemia (CLL) and left cervical lymphadenopathy. An excisional biopsy was performed, and microscopically the lymph node showed effacement of nodal architecture by a tumor composed of spindle cells disposed in intersecting fascicles, and characterized by abundant eosinophilic cytoplasm, elongated nuclei and conspicuous nucleoli. A second population of cells had an epithelioid appearance with intracyto-plasmic vacuoles containing red blood cells. lmmunohistochemically, the tumor cells were positive for CD31 and CD34. The final diagnosis was SEH of the lymph node.
authors.affiliation: Departamento de Patología, Instituto Nacional de Cancerología, México, DF, México. alejandroaviles2001@yahoo.com
authors.forename: Alejandro
authors.initials: A
authors.lastname: Avilés-Salas
authors.forename: José
authors.initials: J
authors.lastname: Cruz Torres-Lucatero
authors.forename: Ximena
authors.initials: X
authors.lastname: Fernandez-Soto
authors.forename: Myrna
authors.initials: M
authors.lastname: Candelaria-Hernández
mesh_terms: D000368:Aged; D006390:Hemangioendothelioma / Q000150:complications / Q000473:pathology*; D006801:Humans; D033162:Incidental Findings; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male