title: Case report: Macrodont mandibular second premolars, a hereditary dental anomaly.
abstract: BACKGROUND
  Macrodontia or megadontia is a rare dental anomaly that refers to teeth that appear larger than normal. Generalised macrodontia may be associated with certain medical conditions and syndromes. Isolated macrodontia involves single teeth, might be the result of teeth fusion and is mainly seen in the incisor area.
  
  
  METHODS
  This paper describes two unrelated cases presenting with bilateral macrodont second lower premolars and the treatment provided. One case demonstrated the anomaly in both the patient and his father.
  
  
  CONCLUSIONS
  This case report suggests for the first time in the literature the genetic aetiology and heritability, as a possible autosomal dominant trait, of this rare dental anomaly.
authors.affiliation: Eastman Dental Institute, University College of London, 256 Gray's Inn Road, London, WC1X 8LD, UK, anna.kyriazidou@nhs.net.
authors.forename: A
authors.initials: A
authors.lastname: Kyriazidou
authors.forename: D
authors.initials: D
authors.lastname: Haider
authors.forename: C
authors.initials: C
authors.lastname: Mason
authors.forename: S
authors.initials: S
authors.lastname: Parekh
authors.forename: A
authors.initials: A
authors.lastname: Bloch-Zupan
mesh_terms: D001641:Bicuspid / Q000002:abnormalities; D005671:Fused Teeth; D006801:Humans; D007180:Incisor / Q000002:abnormalities; D014076:Tooth Diseases