title: Validation of the telephone-administered PHQ-9 against the in-person administered SCID-I major depression module.
abstract: BACKGROUND
  We assessed item-to-item correspondence between the Patient Health Questionnaire-9 (PHQ-9) and the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) major depression episode portion of the major depressive module.
  
  
  METHODS
  Four hundred and ninety-eight soldiers in the Ohio National Guard were administered the PHQ-9 and SCID-I. Data were analyzed using chi-square analyses, logistic regression, receiver operating characteristic (ROC) curve analyses and diagnostic efficiency statistics.
  
  
  RESULTS
  To screen for depression effectively, results indicate use of the cardinal first two items, items representing fatigue, appetite and sleep changes with an item level cut-off point of two, and the item representing suicidal ideation with item level cut-off point of one. Further, total PHQ-9 scores significantly predicted SCID-I major depressive episode (MDE) and diagnosis (MDD) with moderate accuracy. Lastly, the cut-off total score of 10 had the optimal balance of sensitivity and specificity compared to other PHQ-9 scoring options.
  
  
  CONCLUSIONS
  Differences in timeline of administration of the measures, differences in "worst episode" reference between the measures, and use of a specific military population are some of the limitations.
  
  
  CONCLUSIONS
  This validation study provides guidelines for the use of the telephone-administered PHQ-9 in assessing the lifetime prevalence of a major depressive episode and diagnosis in non-clinical populations, with implications for clinical use.
authors.affiliation: Department of Psychiatry, University of Toledo, Toledo, Ohio 43614-2598, USA. Thomas.fine@utoledo.edu
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Fine
authors.forename: Ateka A
authors.initials: AA
authors.lastname: Contractor
authors.forename: Marijo
authors.initials: M
authors.lastname: Tamburrino
authors.forename: Jon D
authors.initials: JD
authors.lastname: Elhai
authors.forename: Marta R
authors.initials: MR
authors.lastname: Prescott
authors.forename: Gregory H
authors.initials: GH
authors.lastname: Cohen
authors.forename: Edwin
authors.initials: E
authors.lastname: Shirley
authors.forename: Philip K
authors.initials: PK
authors.lastname: Chan
authors.forename: Toyomi
authors.initials: T
authors.lastname: Goto
authors.forename: Renee
authors.initials: R
authors.lastname: Slembarski
authors.forename: Israel
authors.initials: I
authors.lastname: Liberzon
authors.forename: Sandro
authors.initials: S
authors.lastname: Galea
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Calabrese
mesh_terms: D000293:Adolescent; D000328:Adult; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000453:epidemiology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D007406:Interview, Psychological / Q000379:methods*; D016015:Logistic Models; D008297:Male; D008403:Mass Screening / Q000379:methods* / Q000706:statistics & numerical data; D008875:Middle Aged; D008889:Military Personnel; D009820:Ohio; D011594:Psychometrics / Q000706:statistics & numerical data; D012372:ROC Curve; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires; D013689:Telephone; D055815:Young Adult
keywords: Depression; National guard soldiers; Patient Health Questionnaire-9; Structured diagnostic interviews