title: [Primary prevention of type 1 diabetes. Actual situation and perspectives].
abstract: The authors presented a review of the actual literature of primary prevention of type 1 diabetes. They stressed a dramatic increase of patients with newly diagnosed diabetes, which was called an epidemic of the XXI century. According to the recently published data, the increase of newly diagnosed cases was more rapid/faster than it was expected/anticipated, and the dramatic increase in the occurrence/prevalence of type 1 diabetes was observed particularly in children up to 5 years of age. Therefore, like it was mentioned by the authors of recently published reports, the necessity of an effective primary prevention of type 1 diabetes also increased. Many clinical trials of primary prevention of type 1 diabetes, in different clinical stages/phases, are currently being conducted. Scientific investigations about an effective primary prevention are now very important, seen as priority problems. Investigations in Poland, which started in the year 2002 and the end of them was established for the year 2017, are also performed as part of an international scientific program. The identification of subjects with a genetic risk of type 1 diabetes is now possible. Very interesting data of a therapy with t-regulatory cells (tregs), especially those received from the umbilical cord blood of newborns are worth emphasizing.
authors.affiliation: Katedra i Klinika Endokrynologii i Diabetologii Wieku Rozwojowego Uniwersytetu Medycznego im. Slaskich we Wrolclawiu. wasikowa@endo.am.wroc.pl
authors.forename: Renata
authors.initials: R
authors.lastname: Wąsikowa
authors.forename: Aleksander
authors.initials: A
authors.lastname: Basiak
mesh_terms: D036101:Cord Blood Stem Cell Transplantation; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology* / Q000517:prevention & control*; D006801:Humans; D015994:Incidence; D011044:Poland / Q000453:epidemiology; D015995:Prevalence; D011322:Primary Prevention / Q000379:methods*; D050378:T-Lymphocytes, Regulatory / Q000637:transplantation