title: Remineralisation of occlusal white spot lesion with a combination of 10% CPP-ACP and 0.2% sodium fluoride evaluated using Diagnodent: a pilot study.
abstract: OBJECTIVE
  To evaluate the efficacy of 10% casein phosphopeptide amorphous calcium phosphate complex (CPP-AC P) used alone or with fluoride as compared to fluoride mouthrinse for the remineralisation of occlusal white spot lesions in an in vivo pilot study.
  
  
  METHODS
  Forty-five subjects with occlusal white spot lesions (WSL) determined by visual examination and confirmed with Diagnodent were randomly divided into 3 groups: group 1: 10% CPP-AC P + 0.2% NaF; group 2: 10% CPPAC P; group 3: 0.5% NaF mouthrinse for 30 days. The pre-treatment and post-intervention Diagnodent values were tabulated and subjected to statistical analysis.
  
  
  RESULTS
  Among the groups, the remineralising potential of 10% CPP-AC P + 0.2% NaF (group 1) and 10% CPP-AC P (group 2) were similar, however, both groups were superior to 0.5% NaF mouthrinse (group 3).
  
  
  CONCLUSIONS
  The CCP-AC P technique is highly beneficial for the remineralisation of non-cavitated occlusal white spot lesions when compared to 0.5% NaF mouthrinse.
authors.affiliation: Department of Conservative Dentistry and Endodontics, Meenakshi Ammal Dental College, Chennai, India. drkrithikadatta@hotmail.com
authors.forename: Jogikalmat
authors.initials: J
authors.lastname: Krithikadatta
authors.forename: Chain
authors.initials: C
authors.lastname: Fredrick
authors.forename: Mohan
authors.initials: M
authors.lastname: Abarajithan
authors.forename: Deivanayagam
authors.initials: D
authors.lastname: Kandaswamy
mesh_terms: D000293:Adolescent; D002327:Cariostatic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002364:Caseins / Q000008:administration & dosage / Q000627:therapeutic use*; D003731:Dental Caries / Q000175:diagnosis / Q000628:therapy*; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007834:Lasers; D008297:Male; D009067:Mouthwashes / Q000627:therapeutic use; D010865:Pilot Projects; D012969:Sodium Fluoride / Q000008:administration & dosage / Q000627:therapeutic use*; D014089:Tooth Remineralization / Q000379:methods*; D014100:Toothpastes / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D002327:Cariostatic Agents; D002364:Caseins; D004338:Drug Combinations; D009067:Mouthwashes; D014100:Toothpastes; C447032:casein phosphopeptide-amorphous calcium phosphate nanocomplex; D012969:Sodium Fluoride