title: Primary cold agglutinin disease: a case report.
abstract: Chronic cold agglutinin disease is a subgroup of auto-immune haemolytic anaemia. Primary cold agglutinin disease has traditionally been defined by the absence of any underlying or associated disease. It usually affects elderly. The term cold refers to the fact that the auto-antibody involved reacts with red cells poorly or not at all at 37 degrees C, whereas it reacts strongly at lower temperature. Here a case of severe pallor, jaundice and red colour urine in winter season for last 10 years diagnosed as a case of primary cold agglutinin disease is reported.The patient was managed conservatively.
authors.affiliation: Department of Medicine, RG Kar Medical College and Hospital, Kolkata.
authors.forename: Susanta Kumar
authors.initials: SK
authors.lastname: Das
authors.forename: Amritava
authors.initials: A
authors.lastname: Ghosh
authors.forename: Niloy
authors.initials: N
authors.lastname: Banerjee
authors.forename: Sudarshan
authors.initials: S
authors.lastname: Khaskil
authors.forename: Sabya Sachi
authors.initials: SS
authors.lastname: Mukherjee
mesh_terms: D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D002908:Chronic Disease; D003116:Color; D006801:Humans; D007565:Jaundice / Q000209:etiology; D008297:Male; D010167:Pallor / Q000209:etiology; D012621:Seasons; D014556:Urine