title: A multicentre randomized trial of combined individual and telephone counselling for smoking cessation.
abstract: OBJECTIVE
  The present study assessed the effectiveness of smoking cessation programs combining individual and telephone counselling, compared to individual or telephone counselling alone.
  
  
  METHODS
  A randomized, multicentre, open-label trial was performed between January 2009 and July 2011 at six smoking cessation clinics in Spain. Of 772 smokers assessed for eligibility, 600 (77%) met inclusion criteria and were randomized. Smokers were randomized to receive individual counselling, combined telephone and individual counselling, or telephone counselling. The primary outcome was biochemically validated continuous abstinence at 52 weeks.
  
  
  RESULTS
  The 52-week abstinence rate was significantly lower in the telephone group compared to the combined group (20.1% vs. 29.0%; OR, 1.32; 95% CI, 1.1-2.7) and to the individual counselling group (20.1% vs. 27.9%; OR, 1.37; 95% CI, 1.0-2.8). The 52-week abstinence rates were not significantly higher in the combined group than the individual group (OR, 0.97; 95% CI, 0.7-1.4).
  
  
  CONCLUSIONS
  Individual counselling and combined individual and telephone counselling were associated with higher 52-week abstinence rates than telephone counselling alone. A combined approach may be highly useful in the clinical treatment of smokers, as it involves less clinic visits than individual counselling alone, thus reducing the program cost, and it increases patient compliance compared to telephone counselling alone.
authors.affiliation: Bellvitge Biomedical Research Institute (IDIBELL), Smoking Cessation Clinic, Preventive Medicine Department, Bellvitge University Hospital, Feixa Llarga s/n 08907 Hospitalet de Llobregat, Barcelona, Spain. jmramon@ub.edu
authors.forename: Josep M
authors.initials: JM
authors.lastname: Ramon
authors.forename: Isabel
authors.initials: I
authors.lastname: Nerin
authors.forename: Araceli
authors.initials: A
authors.lastname: Comino
authors.forename: Cristina
authors.initials: C
authors.lastname: Pinet
authors.forename: Francesc
authors.initials: F
authors.lastname: Abella
authors.forename: José Ma
authors.initials: JM
authors.lastname: Carreras
authors.forename: Marta
authors.initials: M
authors.lastname: Banque
authors.forename: Antoni
authors.initials: A
authors.lastname: Baena
authors.forename: Sergio
authors.initials: S
authors.lastname: Morchon
authors.forename: Adriana
authors.initials: A
authors.lastname: Jimenez-Muro
authors.forename: Adriana
authors.initials: A
authors.lastname: Marqueta
authors.forename: Assumpcio
authors.initials: A
authors.lastname: Vilarasau
authors.forename: Raquel
authors.initials: R
authors.lastname: Bullon
authors.forename: Cristina
authors.initials: C
authors.lastname: Masuet-Aumatell
mesh_terms: D000328:Adult; D001552:Benzazepines / Q000627:therapeutic use; D016642:Bupropion / Q000627:therapeutic use; D003131:Combined Modality Therapy; D037001:Directive Counseling / Q000458:organization & administration*; D018765:Dopamine Uptake Inhibitors / Q000627:therapeutic use; D005260:Female; D015277:Hotlines; D006801:Humans; D008297:Male; D008875:Middle Aged; D018722:Nicotinic Agonists / Q000627:therapeutic use; D010349:Patient Compliance; D011810:Quinoxalines / Q000627:therapeutic use; D016540:Smoking Cessation; D000074606:Smoking Prevention; D013030:Spain; D013689:Telephone; D061485:Tobacco Use Cessation Devices; D016896:Treatment Outcome; D000068580:Varenicline
chemical_list: D001552:Benzazepines; D018765:Dopamine Uptake Inhibitors; D018722:Nicotinic Agonists; D011810:Quinoxalines; D016642:Bupropion; D000068580:Varenicline
keywords: Individual counselling; Randomized multicentre trial; Smoking cessation; Telephone counselling