title: Ten cancer associated genes identified in peripheral blood mononuclear cells from patients with pancreatic adenocarcinoma.
abstract: OBJECTIVE
  Identification of biomarkers for pancreatic cancer may help diagnosis and treatment of patients.
  
  
  METHODS
  This pilot study evaluated potential markers for pancreatic adenocarcinoma (PAC) in peripheral blood mononuclear cells (PBMC). RNA samples were isolated from PBMCs and hybridized to oligonucleotide arrays.
  
  
  RESULTS
  Twenty five-fold leave-two-out analysis identified 10 cancer-associated genes (CAGs). The PAC patients could be identified by the expression profiles of their PBMC with a specificity of 96% and a sensitivity of 80%.
  
  
  CONCLUSIONS
  Ten CAGs were potential new markers in PBMC for patients with PAC.
authors.forename: HaiChao
authors.initials: H
authors.lastname: Yan
authors.forename: Lin
authors.initials: L
authors.lastname: Xu
authors.forename: WenZhi
authors.initials: W
authors.lastname: Jiang
authors.forename: QiuPing
authors.initials: Q
authors.lastname: Xie
authors.forename: Xin
authors.initials: X
authors.lastname: Dong
authors.forename: YuLian
authors.initials: Y
authors.lastname: Wu
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000235:genetics*; D000368:Aged; D005260:Female; D020869:Gene Expression Profiling; D006801:Humans; D007963:Leukocytes, Mononuclear; D008297:Male; D008875:Middle Aged; D020411:Oligonucleotide Array Sequence Analysis; D010190:Pancreatic Neoplasms / Q000097:blood / Q000235:genetics*; D010865:Pilot Projects; D012680:Sensitivity and Specificity; D046888:Tissue Array Analysis