title: Aortic valve replacement in an elderly patient with factor XI deficiency.
abstract: Factor XI (FXI) deficiency is rare and associated with bleeding after surgical procedures. We report a case of an 80-year-old woman with severe aortic valve stenosis. FXI deficiency was diagnosed due to prolonged activated partial thromboplastin time. Aortic valve replacement was performed using a porcine bioprosthetic valve. Intra-operation bleeding was controlled by the transfusion of a fresh frozen plasma. The postoperative course was uneventful.
authors.affiliation: Cardiovascular Surgery Tohoku Phamaceutical University Hospital, 1-12-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8512, Japan, suguruw@hosp.tohoku-pharm.ac.jp.
authors.forename: Suguru
authors.initials: S
authors.lastname: Watanabe
authors.forename: Tadanori
authors.initials: T
authors.lastname: Minagawa
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Kagatani
authors.forename: Makoto
authors.initials: M
authors.lastname: Miura
authors.forename: Kouichi
authors.initials: K
authors.lastname: Tabayashi
mesh_terms: D000369:Aged, 80 and over; D000818:Animals; D001024:Aortic Valve Stenosis / Q000150:complications / Q000601:surgery*; D001705:Bioprosthesis; D016063:Blood Loss, Surgical / Q000517:prevention & control; D005173:Factor XI Deficiency / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006488:Hemostasis, Surgical / Q000379:methods*; D006801:Humans; D010949:Plasma; D013552:Swine