title: Evaluation of a new chemiluminescence immunoassay for laboratory diagnosis of syphilis.
abstract: The purpose of this study was to evaluate diagnostic performances of automated chemiluminescence immunoassay (CLIA) in comparison with Treponema pallidum hemagglutination test (TPHA). The specificity of CLIA was 98.9% and 99.6% for TPHA, whereas the sensitivity was 98% and 96%, respectively. Considering the suitability for automation, CLIA may represent a suitable alternative.
authors.affiliation: Microbiology Service, Virgen de las Nieves University Hospital, 18014 Granada, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Sampedro-Martinez
authors.affiliation: Granada Sanitary District Northeast, 18500 Guadix, Granada, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Padilla-Malo
authors.affiliation: Microbiology Service, Virgen de las Nieves University Hospital, 18014 Granada, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Gomez-Camarasa
authors.affiliation: Microbiology Service, Virgen de las Nieves University Hospital, 18014 Granada, Spain. Electronic address: javierm.rodriguez.sspa@juntadeandalucia.es.
authors.forename: J
authors.initials: J
authors.lastname: Rodriguez-Granger
authors.affiliation: Microbiology Service, Virgen de las Nieves University Hospital, 18014 Granada, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Lara-Oya
mesh_terms: D003955:Diagnostic Tests, Routine / Q000379:methods*; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D049449:Luminescence; D013587:Syphilis / Q000175:diagnosis* / Q000382:microbiology; D014210:Treponema pallidum / Q000302:isolation & purification*
keywords: Antibody; Chemiluminescence; Syphilis; TPHA