title: Delirium with manic and psychotic features associated with amantadine.
abstract: While clinicians are familiar with psychosis as a complication in the long-term treatment with amantadine, rapid psychiatric complications are of much less concern. In the case presented, severe decompensation in mental status occurred within 48 h of initiation of standard doses of amantadine hydrochloride. Clinicians should be alert not only for delayed complications but also for early-onset mental decompensation in elderly patients with influenza A treated with amantadine.
authors.affiliation: Harvard Medical School, Boston MA 02302, USA. Electronic address: adriana.neagoe@state.ma.us.
authors.forename: Adriana D
authors.initials: AD
authors.lastname: Neagoe
mesh_terms: D000369:Aged, 80 and over; D000547:Amantadine / Q000009:adverse effects*; D000998:Antiviral Agents / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000139:chemically induced*; D003693:Delirium / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007251:Influenza, Human / Q000188:drug therapy*; D011605:Psychoses, Substance-Induced / Q000209:etiology*
chemical_list: D000998:Antiviral Agents; D000547:Amantadine
keywords: Amantadine; Delirium; Mania; Psychosis