title: A thioannulation approach to substituted thiophenes from Morita-Baylis-Hillman acetates of acetylenic aldehydes.
abstract: A new protocol has been developed for the synthesis of substituted thiophenes under mild and metal-free reaction conditions via the base-promoted thioannulation of Morita-Baylis-Hillman acetates of acetylenic aldehydes with potassium thioacetate involving a tandem allylic substitution/deacetylative 5-exo-dig-thiocycloisomerization. The obtained products provide an entry to 4H-thieno[3,2-c]chromene and thieno[3,2-c]dihydroquinoline.
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad-500007, India. rajireddy@iict.res.in
authors.forename: Chada Raji
authors.initials: CR
authors.lastname: Reddy
authors.forename: Reddi Rani
authors.initials: RR
authors.lastname: Valleti
authors.forename: Motatipally Damoder
authors.initials: MD
authors.lastname: Reddy
mesh_terms: D000085:Acetates / Q000737:chemistry*; D000447:Aldehydes / Q000737:chemistry*; D015394:Molecular Structure; D013876:Thiophenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000085:Acetates; D000447:Aldehydes; D013876:Thiophenes