title: Fulminate anaerobic bacteremia after chemotherapy for metastatic breast cancer despite the prophylactic use of GCSF.
abstract: Chemotherapy-induced neutropenia often occurs in our routine work and presents an obstacle for adequate (dose and continuance) treatment, which may affect patients' outcome. Granulocyte colony-stimulating factors (GCSFs) effectively prevent myelosuppression and thus improve the standard treatment. Through their application cases of chemotherapy-induced neutropenia have been reduced. Still these factors cannot remove entirely the danger of encountering neutropenia, which can cause dangerous complications. We present a case of a fulminate anaerobic infection with unknown origin in a patient with metastatic breast cancer after standard treatment with chemotherapy supported by GCSFs.
authors.affiliation: Clinic of Hematology and Oncology, Department of Medical Oncology, Medical Military Academy, Sofia, Bulgaria.
authors.forename: Mila
authors.initials: M
authors.lastname: Petrova
authors.forename: Zhasmina
authors.initials: Z
authors.lastname: Mihaylova
authors.forename: Albena
authors.initials: A
authors.lastname: Fakirova
keywords: anaerobic infection; granulocyte colony-stimulating factors; neutropenia; phlegmon