title: Expect the unexpected: clinical trials are key to understanding post-intensive care syndrome.
abstract: Long-term follow-up of randomized prospective trials of treatments in the intensive care unit may allow us to attain some understanding of the causes of post-intensive care syndrome. This in turn may allow us to produce better long-term outcomes among survivors of critical illness.
authors.forename: Michael F
authors.initials: MF
authors.lastname: O'Connor
authors.forename: Mark E
authors.initials: ME
authors.lastname: Nunnally
mesh_terms: D005260:Female; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage*; D007552:Isotonic Solutions / Q000008:administration & dosage*; D008297:Male; D011537:Pruritus / Q000188:drug therapy*; D011788:Quality of Life; D012151:Resuscitation; D018805:Sepsis / Q000188:drug therapy*
chemical_list: D006895:Hydroxyethyl Starch Derivatives; D007552:Isotonic Solutions