title: Muckle-Wells syndrome: individualized, reflare-guided dosing of the orphan drug canakinumab.
authors.affiliation: Department of Dermatology, University Hospital Basel, Switzerland. muellersim@uhbs.ch
authors.forename: Simon M
authors.initials: SM
authors.lastname: Mueller
authors.forename: Peter
authors.initials: P
authors.lastname: Itin
authors.forename: Peter
authors.initials: P
authors.lastname: Haeusermann
mesh_terms: D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized; D056587:Cryopyrin-Associated Periodic Syndromes / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D006801:Humans; D053583:Interleukin-1beta / Q000037:antagonists & inhibitors*; D009965:Orphan Drug Production; D057285:Precision Medicine / Q000379:methods; D012074:Remission Induction / Q000379:methods
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D053583:Interleukin-1beta; C541220:canakinumab