title: Eosinophilic fasciitis as a manifestation of a cutaneous T-cell lymphoma not otherwise specified.
abstract: Eosinophilic fasciitis (EF) is a rare entity characterized by symmetrical and painful thickness and induration of the skin, especially localized on forearms and thorax and generally accompanied by eosinophilia. Although several reports indicate the relationship between EF and hematological disorders such as aplastic anemia, polycythemia vera, or myelomonocytic leukemia, the association with lymphomas is extremely rare. Only a few cases of EF have been previously described preceding or concomitant to the Hodgkin disease, peripheral T-cell lymphoma, B-cell lymphoma, and mycosis fungoides. We report for the first time a 76-year-old man with an EF associated with a peripheral T-cell lymphoma not otherwise specified. We review the relationship between both conditions. In conclusion, we present a unique case of EF as a manifestation of a T-cell lymphoma not otherwise specified. The present case demonstrates the importance of clinical and radiological studies in those cases of EF to rule out a visceral, lymph node, or cutaneous lymphoma.
authors.affiliation: Department of Dermatology and Venereology, 12 de Octubre Hospital, Madrid, Spain. maria.castellanos.gonzalez@gmail.com
authors.forename: María
authors.initials: M
authors.lastname: Castellanos-González
authors.forename: Diego
authors.initials: D
authors.lastname: Velasco Rodriguez
authors.forename: Agustín
authors.initials: A
authors.lastname: Blanco Echevarría
authors.forename: Concha
authors.initials: C
authors.lastname: Postigo
authors.forename: Pablo
authors.initials: P
authors.lastname: Ortiz Romero
authors.forename: Rosa Ayala
authors.initials: RA
authors.lastname: Díaz
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Rodriguez-Peralto
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D004802:Eosinophilia / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D005208:Fasciitis / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000473:pathology; D008297:Male; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D011237:Predictive Value of Tests; D012867:Skin / Q000276:immunology / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor