title: Pancreatic enzyme replacement therapy for enterally fed patients with cystic fibrosis.
abstract: Administration of pancreatic enzymes (pancrelipase) to adult patients with cystic fibrosis when receiving enteral nutrition through a feeding tube is challenging. A number of techniques for preparing and administering the drug may result in complications that include feeding tube occlusion and inadequate enzyme delivery to the patient. A series of inpatient encounters is described.
authors.affiliation: Clinical Nutrition Support Services at the Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
authors.forename: Michele
authors.initials: M
authors.lastname: Nicolo
authors.forename: Kathleen W
authors.initials: KW
authors.lastname: Stratton
authors.forename: Wanda
authors.initials: W
authors.lastname: Rooney
authors.forename: Joseph
authors.initials: J
authors.lastname: Boullata
mesh_terms: D000328:Adult; D003550:Cystic Fibrosis / Q000150:complications / Q000201:enzymology / Q000628:therapy*; D004750:Enteral Nutrition / Q000009:adverse effects / Q000379:methods*; D056947:Enzyme Replacement Therapy; D010188:Exocrine Pancreatic Insufficiency / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D020799:Pancrelipase / Q000008:administration & dosage / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D020799:Pancrelipase
keywords: cystic fibrosis; enteral nutrition; enzymes; food-drug interactions; pancreas