title: Use of RE-AIM to Address Health Inequities: Application in a low-income community health center based weight loss and hypertension self-management program.
abstract: While health inequities are well documented, and there are helpful frameworks to understand health disparities, implementation frameworks are also needed to focus the design, evaluation and reporting on interventions targeting populations at increased risk.
  
  
  
  Describe how the RE-AIM framework (Reach, Effectiveness, Adoption, Implementation, and Maintenance) can be used for these purposes and illustrate its application in the context of a randomized, pragmatic weight-loss and hypertension self-management intervention.
  
  
  
  RE-AIM was used to both plan and evaluate the Be Fit Be Well program for urban community health center patients.
  
  
  
  The RE-AIM framework helped to focus attention on and produce high rates of adoption and reach. Implementation rates varied across components. Weight losses were statistically significant, but not clinically significant. They were robust across a variety of patient characteristics, and the program was relatively low cost. Individual weight losses and blood pressure reductions were maintained throughout the 24-month period, but the program was not sustained at any of the three settings.
  
  
  
  Implementation frameworks such as RE-AIM can help design pragmatic interventions that focus on both the context for disparities reduction and the ultimate goal of public health impact.
authors.affiliation: Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD.
authors.forename: Russell E
authors.initials: RE
authors.lastname: Glasgow
authors.forename: Sandy
authors.initials: S
authors.lastname: Askew
authors.forename: Peyton
authors.initials: P
authors.lastname: Purcell
authors.forename: Erica
authors.initials: E
authors.lastname: Levine
authors.forename: Erica T
authors.initials: ET
authors.lastname: Warner
authors.forename: Kurt C
authors.initials: KC
authors.lastname: Stange
authors.forename: Graham A
authors.initials: GA
authors.lastname: Colditz
authors.forename: Gary G
authors.initials: GG
authors.lastname: Bennett
keywords: RE-AIM; Weight-loss; health disparities; implementation science; low-income; pragmatic trial