title: Juvenile nasopharyngeal angiofibroma: Timisoara ENT Department's experience.
abstract: Juvenile nasopharyngeal angiofibroma is a histologically benign, but very aggressive and destructive tumor found exclusively in young males. The management of juvenile nasopharyngeal angiofibroma has changed in recent years, but it still continues to be a challenge for the multidisciplinary head and neck surgical team.
  
  
  OBJECTIVE
  The purpose of this study was to review a series of 30 patients describing the treatment approach used and studying the outcome of juvenile nasopharyngeal angiofibroma in the ENT Department Timisoara, Romania for a period of 30 years.
  
  
  METHODS
  The patients were diagnosed and treated during the years 1981-2011. All patients were male. Tumors were classified using Radkowski's staging system. Computed tomography and magnetic resonance imaging allowed for accurate diagnosis and staging of the tumors. Biopsies were not performed. Surgery represented the gold standard for treatment of juvenine nasopharyngeal angiofibroma. All patients had the tumor removed by an external approach, endoscopic surgical approach not being employed in this series of patients.
  
  
  RESULTS
  All patients were treated surgically. Surgical techniques performed were: Denker-Rouge technique in 13 cases (43.33%), paralateronasal technique in 7 cases (23.33%), retropalatine technique in 5 cases (16.66%) and transpalatine technique in 5 cases (16.66%). No preoperative tumor embolization was performed. The recurrence rate was 16.66%. The follow-up period ranged from 1 year to 12 years.
  
  
  CONCLUSIONS
  Management of juvenile nasopharyngeal angiofibroma remains a surgical challenge. Clinical evaluation and surgical experience are very important in selecting the proper approach. A multidisciplinary team, with an experienced surgeon and good collaboration with the anesthesiologist are needed for successful surgical treatment.
authors.affiliation: Department of Otolaryngology, Victor Babes University of Medicine and Pharmacy Timisoara, Romania. giovanescu@gmail.com
authors.forename: Gheorghe
authors.initials: G
authors.lastname: Iovanescu
authors.forename: Steluta
authors.initials: S
authors.lastname: Ruja
authors.forename: Stan
authors.initials: S
authors.lastname: Cotulbea
mesh_terms: D000293:Adolescent; D018322:Angiofibroma / Q000473:pathology / Q000601:surgery*; D002648:Child; D004724:Endoscopy; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome