title: [Study on the molecular epidemiological characteristics of norovirus in acute gastroenteritis of Beijing].
abstract: OBJECTIVE
  To study the prevalence, genotypes and molecular characteristics of norovirus (NoV) in acute gastroenteritis.
  
  
  METHODS
  RT-PCR was used to determine the molecular epidemiology of NoV.
  
  
  RESULTS
  Out of 685 samples, 66 positive specimens were identified and the prevalence was 9.6% (66/685), 9.9% in males and 9.4% in females, respectively, with no significant difference. The prevalence rates showed no differences between age groups or between inpatients and outpatients. NoV gastroenteritis did not present any seasonal distribution. 43 out of the 66 specimens were classified, with 10 (22.7%) belonged to GI including 2 GI.3, 1 GI.4, 4 GI.5 and 3 GI.7. Other 33 (77.3%) belonged to GII genogroup, including GII.4 accounted for 60.6% (20/33) and followed by 7 GII.12, 2 GII.6, 1 GII.2, 1 GII.3, 1 GII.5. Six specimens mixed with GI and GII and 3 specimens were classified as GI.3/GII.7, GI.5/GII.5 and GI.4/GII.4.
  
  
  CONCLUSIONS
  The main symptoms of acute gastroenteritis were abdominal pain, nausea, vomit and fever. There were many genotypes identified in our study and the main genotypes were GII.4/2006a and 2006b. GI and GII could be coinfected with each other.
authors.affiliation: Department of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China.
authors.forename: Shao-wei
authors.initials: SW
authors.lastname: Sang
authors.forename: Zhong-tang
authors.initials: ZT
authors.lastname: Zhao
authors.forename: Ji-jiang
authors.initials: JJ
authors.lastname: Suo
authors.forename: Yu-bin
authors.initials: YB
authors.lastname: Xing
authors.forename: Ning
authors.initials: N
authors.lastname: Jia
authors.forename: Yan
authors.initials: Y
authors.lastname: Gao
authors.forename: Ming-mei
authors.initials: MM
authors.lastname: DU
authors.forename: Li-jun
authors.initials: LJ
authors.lastname: Xie
authors.forename: Bo-wei
authors.initials: BW
authors.lastname: Liu
authors.forename: Shi-wang
authors.initials: SW
authors.lastname: Ren
authors.forename: Yun-xi
authors.initials: YX
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000821:virology; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D029322:Norovirus / Q000235:genetics*; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D055815:Young Adult
chemical_list: D012367:RNA, Viral