title: [Complications of corneal cross-linking].
abstract: BACKGROUND
  More than 10 years after the clinical introduction of corneal cross-linking (CXL) the indications and contraindications are still not yet defined. Fundamental for such a list is the incidence of complications.
  
  
  METHODS
  A PubMed search for complications of corneal crosslinking published up to March 2013 was carried out.
  
  
  RESULTS
  The published complication rates ranged from 1 % to 10 % depending on the stage of keratoconus. Early postoperative complications were transient stromal haze, sterile infiltrates, endothelium decompensation, delayed epithelial healing and infectious keratitis. Stromal opacity can be a delayed postoperative event.
  
  
  CONCLUSIONS
  Complications after corneal cross-linking treatment for keratoconus are rare but the management of these complications may need keratoplasty.
authors.affiliation: Institut für Refraktive und Ophthalmo-Chirurgie, Stockerstr. 37, 8002, Zürich, Schweiz. theo@seiler.tv
authors.forename: T G
authors.initials: TG
authors.lastname: Seiler
authors.forename: G
authors.initials: G
authors.lastname: Schmidinger
authors.forename: I
authors.initials: I
authors.lastname: Fischinger
authors.forename: T
authors.initials: T
authors.lastname: Koller
authors.forename: T
authors.initials: T
authors.lastname: Seiler
mesh_terms: D015897:Comorbidity; D006801:Humans; D015994:Incidence; D007634:Keratitis / Q000453:epidemiology* / Q000517:prevention & control*; D007640:Keratoconus / Q000453:epidemiology* / Q000601:surgery*; D017319:Photosensitizing Agents / Q000627:therapeutic use; D011183:Postoperative Complications / Q000453:epidemiology* / Q000517:prevention & control*; D012307:Risk Factors; D014467:Ultraviolet Therapy / Q000706:statistics & numerical data*
chemical_list: D017319:Photosensitizing Agents