title: Two rare cases of retinal vasculitis following vaccination.
abstract: We write to report two rare cases of retinal vasculitis following administration of vaccinations. Both patients received recent vaccinations (within 4 weeks and 2 months respectively) and presented with unilateral visual loss due to retinal arteriolar vasculitis. Investigations did not reveal any other causes of vasculitis. The first patient's ocular inflammation settled following periocular steroid injection, whereas the second patient required the additional use of oral corticosteroid. Both patients had improved vision following treatment. Vaccinations can cause an autoimmune reaction. Systemic vasculitis has previously been described, whereas ocular vasculitic involvement is also possible but extremely rare. When seeing a patient with visual loss due to retinal vasculitis of unknown aetiology, a history of any recent vaccinations should be elicited.
authors.affiliation: Ophthalmology Registrar, Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff , UK. kwokthy@hotmail.com
authors.forename: T
authors.initials: T
authors.lastname: Kwok
authors.forename: A
authors.initials: A
authors.lastname: Al-Bermani
mesh_terms: D022422:Diphtheria-Tetanus Vaccine / Q000009:adverse effects; D022362:Hepatitis A Vaccines / Q000009:adverse effects; D006801:Humans; D007252:Influenza Vaccines / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D023321:Poliovirus Vaccines / Q000009:adverse effects; D011859:Radiography; D031300:Retinal Vasculitis / Q000209:etiology*; D012171:Retinal Vessels / Q000000981:diagnostic imaging; D014436:Typhoid-Paratyphoid Vaccines / Q000009:adverse effects; D014612:Vaccines / Q000009:adverse effects*
chemical_list: D022422:Diphtheria-Tetanus Vaccine; D022362:Hepatitis A Vaccines; D007252:Influenza Vaccines; D023321:Poliovirus Vaccines; D014436:Typhoid-Paratyphoid Vaccines; D014612:Vaccines
keywords: Retinitis; autoimmune; immunisation; vaccination; vasculitis