title: BSE-associated prion-amyloid cardiomyopathy in primates.
abstract: Prion amyloidosis occurred in the heart of 1 of 3 macaques intraperitoneally inoculated with bovine spongiform encephalopathy prions. This macaque had a remarkably long duration of disease and signs of cardiac distress. Variant Creutzfeldt-Jakob disease, caused by transmission of bovine spongiform encephalopathy to humans, may manifest with cardiac symptoms from prion-amyloid cardiomyopathy.
authors.affiliation: University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
authors.forename: Susanne
authors.initials: S
authors.lastname: Krasemann
authors.forename: Giulia
authors.initials: G
authors.lastname: Mearini
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Krämer
authors.forename: Katja
authors.initials: K
authors.lastname: Wagenführ
authors.forename: Walter
authors.initials: W
authors.lastname: Schulz-Schaeffer
authors.forename: Melanie
authors.initials: M
authors.lastname: Neumann
authors.forename: Walter
authors.initials: W
authors.lastname: Bodemer
authors.forename: Franz-Josef
authors.initials: FJ
authors.lastname: Kaup
authors.forename: Michael
authors.initials: M
authors.lastname: Beekes
authors.forename: Lucie
authors.initials: L
authors.lastname: Carrier
authors.forename: Adriano
authors.initials: A
authors.lastname: Aguzzi
authors.forename: Markus
authors.initials: M
authors.lastname: Glatzel
mesh_terms: D000686:Amyloidosis / Q000473:pathology*; D000818:Animals; D001921:Brain / Q000473:pathology; D009202:Cardiomyopathies / Q000209:etiology* / Q000473:pathology*; D002417:Cattle; D007562:Creutzfeldt-Jakob Syndrome / Q000473:pathology* / Q000635:transmission*; D016643:Encephalopathy, Bovine Spongiform / Q000473:pathology / Q000635:transmission*; D008253:Macaca mulatta; D018482:Muscle, Skeletal / Q000473:pathology; D009206:Myocardium / Q000473:pathology
keywords: BSE; PrPSc; bovine spongiform encephalopathy; cardiomyopathy; primates; prions; vCJD; variant Creutzfeldt-Jakob disease