title: Applications of multifactor dimensionality reduction to genome-wide data using the R package 'MDR'.
abstract: This chapter describes how to use the R package 'MDR' to search and identify gene-gene interactions in high-dimensional data and illustrates applications for exploratory analysis of multi-locus models by providing specific examples.
authors.affiliation: Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
authors.forename: Stacey
authors.initials: S
authors.lastname: Winham
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D004843:Epistasis, Genetic; D015894:Genome, Human; D055106:Genome-Wide Association Study; D006801:Humans; D058011:Multifactor Dimensionality Reduction; D020641:Polymorphism, Single Nucleotide; D012641:Selection, Genetic; D012984:Software