title: [Antibodies to endogenous bioregulators and their association with age and sex in chronic pain syndrome].
abstract: Authors studied changes in the levels of antibodies to endogenous bioregulators (Ab) to Β-endorphin, orphanin, serotonin, dopamine and angiotensin in 36 healthy people and 109 patients with dorsopathy with chronic pain syndrome. The association of these immunological indicators with age and sex was found. It has been concluded that the levels of Ab to endogenous bioregulators may be considered as a marker of algic system pathology that does not depend on age and is sex-related.
authors.affiliation: Moscow Clinical Research Center of Narcology, Moscow, Russia
authors.forename: M A
authors.initials: MA
authors.lastname: Myagkova
authors.forename: S N
authors.initials: SN
authors.lastname: Petrochenko
authors.forename: V S
authors.initials: VS
authors.lastname: Morozova
authors.forename: I A
authors.initials: IA
authors.lastname: Moseikin
authors.forename: V V
authors.initials: VV
authors.lastname: Shypitsin
authors.forename: O Yu
authors.initials: OY
authors.lastname: Polyvyanaya
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000809:Angiotensins / Q000276:immunology; D000906:Antibodies / Q000097:blood* / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D059350:Chronic Pain / Q000097:blood / Q000276:immunology*; D004298:Dopamine / Q000276:immunology; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology; D008297:Male; D008875:Middle Aged; D018847:Opioid Peptides / Q000276:immunology; D012701:Serotonin / Q000276:immunology; D012737:Sex Factors; D013118:Spinal Cord Diseases / Q000097:blood / Q000276:immunology; D001615:beta-Endorphin / Q000276:immunology; D000097629:Nociceptin
chemical_list: D000809:Angiotensins; D000906:Antibodies; D015415:Biomarkers; D004298:Dopamine; D018847:Opioid Peptides; D012701:Serotonin; D001615:beta-Endorphin; D000097629:Nociceptin