title: Visual detection of copper(II) ions based on an anionic polythiophene derivative using click chemistry.
abstract: We have developed a novel approach for the rapid visual detection of Cu(2+) based on an anionic polythiophene derivative (sodium poly(2-(4-methyl-3-thienyloxy)propanesulfonate, PMTPS) using click chemistry. The method relies on the disassembly of PMTPS aggregates in the presence of cationic surfactant through electrostatic and hydrophobic interactions. In the assay of Cu(2+) detection, a cationic surfactant was formed via a click reaction catalyzed by copper(I), which was derived in situ from copper(II) and promoted the disassembly of PMTPS aggregates leading to the distinct solution color change from purple to yellow. This polymer probe has excellent sensitivity and selectivity for Cu(2+) with a detectable range in the micromolar regime by naked eyes and can be used for monitoring Cu(2+) concentrations below the safety limit in real-world samples.
authors.affiliation: Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China.
authors.forename: Zhiyi
authors.initials: Z
authors.lastname: Yao
authors.forename: Yanbo
authors.initials: Y
authors.lastname: Yang
authors.forename: Xueliang
authors.initials: X
authors.lastname: Chen
authors.forename: Xianping
authors.initials: X
authors.lastname: Hu
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.forename: Yuliang
authors.initials: Y
authors.lastname: Zhao
authors.forename: Hai-Chen
authors.initials: HC
authors.lastname: Wu
mesh_terms: D057930:Click Chemistry / Q000379:methods*; D003300:Copper / Q000737:chemistry*; D018625:Microscopy, Atomic Force / Q000379:methods; D011108:Polymers / Q000737:chemistry*; D013876:Thiophenes / Q000737:chemistry*
chemical_list: D011108:Polymers; D013876:Thiophenes; C066730:polythiophene; D003300:Copper