title: Tea consumption and the risk of oral cancer incidence: a case-control study from China.
abstract: OBJECTIVE
  To evaluate the relation of tea consumption with the risk of oral cancer incidence.
  
  
  METHODS
  A multicenter case-control study based on hospitalized population was conducted for evaluating the association of tea consumption with oral cancer risk in China. Black tea and green tea were separately analyzed. 723 cases and 857 controls were included. Unconditional multiple logistic regression model was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) of oral cancer for tea consumption.
  
  
  RESULTS
  The ORs for green tea consumption⩾8g/day compared with<4g/day were 0.72 (95% CI 0.54, 0.93) for men, and 0.93 (95% CI 0.74, 1.26) for women. The ORs for black tea consumption⩾6g/day compared with<2g/day were 0.97 (95% CI 0.74, 1.20) for men, and 0.91 (95% CI 0.68, 1.23) for women. Green tea intake was significantly associated with reduced risk of oral cancer in men, but not in women, and the association was stronger in heavily smoking men. There was no indication that black tea consumption was associated with decreased oral cancer risk.
  
  
  CONCLUSIONS
  The results of this study indicated that green tea consumption may decrease the risk of oral cancer in men especially for those smoking heavily.
authors.affiliation: Department of Oral & Maxillofacial - Head & Neck Oncology, Ninth People's Hospital, School of Medicine, Jiao Tong University, Shanghai 200011, China. Electronic address: fjy0712@hotmail.com.
authors.forename: Jin-Ye
authors.initials: JY
authors.lastname: Fu
authors.affiliation: Department of Epidemiology, Shanghai Cancer Institute, Shanghai 200032, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Gao
authors.affiliation: Department of Oral & Maxillofacial - Head & Neck Oncology, Ninth People's Hospital, School of Medicine, Jiao Tong University, Shanghai 200011, China. Electronic address: zhzhy639@163.com.
authors.forename: Zhi-Yuan
authors.initials: ZY
authors.lastname: Zhang
authors.affiliation: Department of Oral & Maxillofacial - Head & Neck Oncology, Ninth People's Hospital, School of Medicine, Jiao Tong University, Shanghai 200011, China. Electronic address: zhjw@omschina.org.cn.
authors.forename: Jia-Wei
authors.initials: JW
authors.lastname: Zheng
authors.affiliation: Department of Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China.
authors.forename: Jian-Feng
authors.initials: JF
authors.lastname: Luo
authors.affiliation: Department of Oral & Maxillofacial - Head & Neck Oncology, Ninth People's Hospital, School of Medicine, Jiao Tong University, Shanghai 200011, China.
authors.forename: Lai-Ping
authors.initials: LP
authors.lastname: Zhong
authors.affiliation: Department of Epidemiology, Shanghai Cancer Institute, Shanghai 200032, China.
authors.forename: Yong-Bing
authors.initials: YB
authors.lastname: Xiang
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000453:epidemiology*; D012307:Risk Factors; D013662:Tea
chemical_list: D013662:Tea
keywords: Black tea; Case-control study; Green tea; Oral cancer; Risk factors; Smoking; Tea consumption