title: Ischemic (functional) mitral regurgitation.
abstract: Mitral regurgitation (MR) is a frequent complication of myocardial infarction and coronary artery disease that is associated with adverse prognosis. The main mechanism of ischemic MR relates to distortion of the spatial relationships between the mitral valve and papillary muscles secondary to ventricular remodeling. The evidence that treatment of ischemic MR improves long-term survival still remains unclear, and further studies are needed to determine whether correcting ischemic MR will improve survival and/or symptoms.
authors.affiliation: Echocardiography, Blake 256, Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114-2696, USA. jhung@partners.org
authors.forename: Judy W
authors.initials: JW
authors.lastname: Hung
mesh_terms: D004452:Echocardiography / Q000379:methods; D006801:Humans; D008943:Mitral Valve / Q000033:anatomy & histology / Q000000981:diagnostic imaging* / Q000473:pathology; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D017202:Myocardial Ischemia / Q000150:complications*; D010210:Papillary Muscles / Q000033:anatomy & histology