title: [Evaluation of DCA vantage for rapid in-clinic measurement of HbA1c on capillary blood in young type 1 diabetic patients].
abstract: Rapid in clinic measurement of glycated hemoglogin (HbA1c) allows to determine the level of metabolic control within a few minutes on capillary blood. We have evaluated the new DCA Vantage (Siemens) based on an immunological technique, replacing the DCA 2000+ (Siemens). The study included 120 unselected young type 1 diabetic patients, with different degrees of metabolic control. The DCA Vantage was compared with the HPLC system (Menarini HA 8160) whose deviation from the DCCT was < 0.1% across the clinical range. The mean underestimation of the DCA Vantage was -0.40%. The agreement limits (+/- 1.96 SD) were between 0.14% and -0.93%; this means +/- 0.53% around -0.40%. In conclusion, the DCA Vantage underestimates HbA1c levels; however it met the acceptance criteria of having a coefficient of variation < 3%.
authors.affiliation: Clinique de Diabétologie, H.U.D.E.R.F. elarabihouda@hotmail.com
authors.forename: H
authors.initials: H
authors.lastname: El Arabi
authors.forename: D
authors.initials: D
authors.lastname: Willems
authors.forename: C
authors.initials: C
authors.lastname: Mélot
authors.forename: H
authors.initials: H
authors.lastname: Dorchy
mesh_terms: D000293:Adolescent; D001774:Blood Chemical Analysis / Q000379:methods; D002196:Capillaries; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D013997:Time Factors
chemical_list: D006442:Glycated Hemoglobin