title: Partition, sorption and structure activity relation study of dialkoxybenzenes that modulate insect behavior.
abstract: Some dialkoxybenzenes are promising new insect control agents. These compounds mimic naturally occurring odorants that modulate insect behavior. Before applying these compounds, however, their persistence and biodegradability at the application site and in the environment should be understood. The fate of organic compounds in the environment is a complex phenomenon which is influenced by many processes such as sorption to soil components, sedimentation, volatilization, and uptake by plants, as well as biotic and abiotic chemical degradation. In this study, the octanol-water partition coefficient, volatility and sorption on soil components (sand, clay and organic matter) of selected dialkoxybenzenes as well as structure activity relationships with regard to partition, volatility and sorption were investigated. Additionally, calculations of partition, molar volume and molecular surface areas were done, to understand structure-activity relationships of the physical properties.
authors.affiliation: Simon Fraser University, Department of Chemistry, 8888 University Drive, Burnaby, BC, Canada V5A 1S6. pebrahim@sfu.ca
authors.forename: Parisa
authors.initials: P
authors.lastname: Ebrahimi
authors.forename: Jacob
authors.initials: J
authors.lastname: Spooner
authors.forename: Noham
authors.initials: N
authors.lastname: Weinberg
authors.forename: Erika
authors.initials: E
authors.lastname: Plettner
mesh_terms: D000327:Adsorption; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001554:Benzene / Q000737:chemistry* / Q000494:pharmacology*; D057927:Hydrophobic and Hydrophilic Interactions; D007306:Insecticides / Q000737:chemistry* / Q000494:pharmacology*; D007536:Isomerism; D000442:Octanols / Q000737:chemistry; D013329:Structure-Activity Relationship; D013499:Surface Properties; D014835:Volatilization; D014867:Water / Q000737:chemistry
chemical_list: D007306:Insecticides; D000442:Octanols; D014867:Water; D001554:Benzene
keywords: Dialkoxybenzenes; Octanol–water partition coefficient; Pesticide fate; Sorption; Volatilization