title: Disease presentation, treatment and survival for Italian colorectal cancer patients: a EUROCARE high resolution study.
abstract: We analysed presentation, treatment and survival in a representative population-based sample of 3753 Italian colorectal cancer cases, diagnosed 2003-05: 70% were >65 years, 44% stage I-II, 27% stage IV and 92% received surgery. Chemotherapy was given to 58% of stage III colon cases, radiotherapy to 25% of rectal cases. Four percent of surgical cases underwent endoscopic polypectomy, and in 57% ≥11 lymph nodes were examined. Five-year relative survival was good (60%), independent of sex and site. Adherence to treatment guidelines was satisfactory, but wider use of faecal blood testing and colonoscopy will anticipate stage at diagnosis and likely improve survival.
authors.affiliation: 1 Analytical Epidemiology and Health Impact Unit, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
authors.forename: Pamela
authors.initials: P
authors.lastname: Minicozzi
authors.forename: Shaniko
authors.initials: S
authors.lastname: Kaleci
authors.forename: Stefania
authors.initials: S
authors.lastname: Maffei
authors.forename: Claudia
authors.initials: C
authors.lastname: Allemani
authors.forename: Adriano
authors.initials: A
authors.lastname: Giacomin
authors.forename: Adele
authors.initials: A
authors.lastname: Caldarella
authors.forename: Francesco
authors.initials: F
authors.lastname: Iachetta
authors.forename: Mario
authors.initials: M
authors.lastname: Fusco
authors.forename: Rosario
authors.initials: R
authors.lastname: Tumino
authors.forename: Massimo
authors.initials: M
authors.lastname: Vicentini
authors.forename: Fabio
authors.initials: F
authors.lastname: Falcini
authors.forename: Rosaria
authors.initials: R
authors.lastname: Cesaraccio
authors.forename: Maurizio
authors.initials: M
authors.lastname: Ponz de Leon
authors.forename: Milena
authors.initials: M
authors.lastname: Sant
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D005260:Female; D019983:Guideline Adherence / Q000706:statistics & numerical data; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D016019:Survival Analysis; D055815:Young Adult