title: Effect of andiroba oil on periodontitis in Wistar rats.
abstract: OBJECTIVE
  To evaluate the effects of andiroba oil on the periodontitis in rats.
  
  
  METHODS
  The periodontitis was induced by the placement of cotton ligatures around the cervix of the second upper molars on fifteen rats, and waiting fifty days. The animals were randomly distributed into three groups: saline group, andiroba oil group and meloxican group, differentiated by substance used in the treatment of periodontitis. The groups received the respective substance by gavage for seven days, after the periodontitis induced. It was analyzed the score of inflammatory cells and the measurement from the cemento-enamel junction to the bone crest.
  
  
  RESULTS
  The andiroba oil group (p=0.008) and meloxican group (p=0.0347) show a less score of inflammatory cells than saline group, however there weren't difference between them (p=0.2754). Regarding the analysis of measurement from the cemento-enamel junction to the bone crest, there was no difference between groups studied (p=0.3451).
  
  
  CONCLUSIONS
  Andiroba oil decreased the quantity of inflammatory cells, however, it didn't have an effect on the measurement of alveolar bone loss, like the treatment with Meloxican®.
authors.affiliation: Postgraduate Program in Odontology, UFPA, Belem-PA, Brazil. glaubrc@hotmail.com
authors.forename: Glaucia Babeto
authors.initials: GB
authors.lastname: Carmona
authors.forename: Renan Kleber Costa
authors.initials: RK
authors.lastname: Teixeira
authors.forename: Marcus Vinicius Henriques
authors.initials: MV
authors.lastname: Brito
authors.forename: Flavia Sirotheau Correa
authors.initials: FS
authors.lastname: Pontes
authors.forename: Eloisa Helena Aguiar
authors.initials: EH
authors.lastname: Andrade
authors.forename: Felipe Paiva
authors.initials: FP
authors.lastname: Fonseca
authors.forename: Ricardo Miranda Brito
authors.initials: RM
authors.lastname: Costa
authors.forename: Francideise Martins
authors.initials: FM
authors.lastname: Carvalho
mesh_terms: D016301:Alveolar Bone Loss / Q000473:pathology; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002452:Cell Count; D007249:Inflammation / Q000473:pathology; D008297:Male; D029582:Meliaceae / Q000737:chemistry*; D010518:Periodontitis / Q000188:drug therapy* / Q000473:pathology; D010938:Plant Oils / Q000627:therapeutic use*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D019237:Tooth Cervix / Q000187:drug effects / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D010938:Plant Oils