title: Primo vascular system accompanying a blood vessel from tumor tissue and a method to distinguish it from the blood or the lymph system.
abstract: A primo vessel was observed in the abdominal cavity in the lung cancer mouse model, and its function as an extra metastatic path was observed. In this work, we found a primo vessel accompanying a blood vessel emanating from a tumor in the skin. We also presented simple and efficient criteria to distinguish a primo vessel from a blood or a lymph vessel and from a nerve. The criteria for using DAPI and Phalloidin will be useful in clinical situations to find and identify the primo vessels among the blood vessels, lymph vessels, or nerves in the tissue surrounding a tumor such as a melanoma or breast cancer.
authors.affiliation: Nano-Primo Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon 443-270, Republic of Korea.
authors.forename: Jaekwan
authors.initials: J
authors.lastname: Lim
authors.forename: Sungwoo
authors.initials: S
authors.lastname: Lee
authors.forename: Zhendong
authors.initials: Z
authors.lastname: Su
authors.forename: Hong Bae
authors.initials: HB
authors.lastname: Kim
authors.forename: Jung Sun
authors.initials: JS
authors.lastname: Yoo
authors.forename: Kwang-Sup
authors.initials: KS
authors.lastname: Soh
authors.forename: Sungchul
authors.initials: S
authors.lastname: Kim
authors.forename: Yeon Hee
authors.initials: YH
authors.lastname: Ryu