title: A case of locally advanced well-differentiated fetal adenocarcinoma of the lung treated with concurrent chemoradiation therapy.
abstract: Fetal adenocarcinoma is a rare adenocarcinoma subtype of pulmonary blastoma. A 48-year-old male patient is being referred to our hospital due to progressive dyspnea. A chest X-ray showed a lung mass of unknown origin that was obstructing the right main bronchus. After relieving the airway obstruction with stent insertion via bronchoscopy, a diagnosis of fetal adenocarcinoma is being confirmed through thoracoscopic biopsy. Due to the locally advanced state of the lung cancer, it seemed to be inoperable, and concurrent chemo-radiation therapy was being administered with docetaxel. The stent was removed after improvements in the airway obstruction followed by a lung mass shrinkage. Comparing to other contexts which describe fetal adenocarcinoma as lower grade malignancy with low-associated mortality, herein, we describe a case of locally-advanced fetal adenocarcinoma (T4N3M0). This is the first documented case being treated with concurrent chemoradiation therapy. The followed-up image studies represent a partial response and the patient is currently under further observations.
authors.affiliation: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Chanhee
authors.initials: C
authors.lastname: Kyung
authors.forename: Sang Young
authors.initials: SY
authors.lastname: Kim
authors.forename: Beom Jin
authors.initials: BJ
authors.lastname: Lim
authors.forename: Jung-Joon
authors.initials: JJ
authors.lastname: Cha
authors.forename: Hyung Jung
authors.initials: HJ
authors.lastname: Kim
authors.forename: Chul Min
authors.initials: CM
authors.lastname: Ahn
authors.forename: Heejin
authors.initials: H
authors.lastname: Park
authors.forename: Eun Na
authors.initials: EN
authors.lastname: Cho
authors.forename: Yoon Soo
authors.initials: YS
authors.lastname: Chang
keywords: Adenocarcinoma; Drug Therapy; Radiotherapy