title: Vulvar and vaginal HPV disease.
abstract: Human papilloma virus is associated with a multitude of lower genital tract diseases in women in addition to cervical cancer, including genital warts, vulvar intraepithelial neoplasia, vaginal intraepithelial neoplasia, and some vulvar, vaginal, and anal cancers that are associated with oncogenic subtypes. The degree to which HPV manifests pathology depends on viral type, host immune response, and local environmental factors. This article reviews the evaluation and management of the following vulvar and vaginal human papilloma virus diseases: condyloma, vulvar intraepithelial neoplasia, and vaginal intraepithelial neoplasia. Included is a brief discussion of the association with vulvar and vaginal cancer.
authors.affiliation: Department of Obstetrics & Gynecology, University of Texas, San Antonio, TX 78229, USA.
authors.forename: Erin L
authors.initials: EL
authors.lastname: Nelson
authors.forename: Colleen K
authors.initials: CK
authors.lastname: Stockdale
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000634:Aminoquinolines / Q000627:therapeutic use; D000970:Antineoplastic Agents; D002278:Carcinoma in Situ / Q000175:diagnosis / Q000628:therapy / Q000821:virology; D003127:Colposcopy; D003218:Condylomata Acuminata / Q000188:drug therapy / Q000601:surgery / Q000821:virology; D005260:Female; D052140:Human papillomavirus 11; D052163:Human papillomavirus 6; D006801:Humans; D000077271:Imiquimod; D007369:Interferon Inducers; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D030361:Papillomavirus Infections / Q000188:drug therapy / Q000517:prevention & control / Q000601:surgery; D053918:Papillomavirus Vaccines; D011034:Podophyllotoxin / Q000627:therapeutic use; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012749:Sexually Transmitted Diseases / Q000821:virology; D014238:Trichloroacetic Acid / Q000627:therapeutic use; D014623:Vaginal Diseases / Q000821:virology*; D014625:Vaginal Neoplasms / Q000175:diagnosis / Q000628:therapy / Q000821:virology; D014626:Vaginal Smears; D014845:Vulvar Diseases / Q000821:virology*; D014846:Vulvar Neoplasms / Q000175:diagnosis / Q000628:therapy / Q000821:virology; D055815:Young Adult
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D007369:Interferon Inducers; D053918:Papillomavirus Vaccines; D014238:Trichloroacetic Acid; D011034:Podophyllotoxin; D000077271:Imiquimod