title: Primary synovial sarcoma of the lung successfully resected under temporary bypass.
abstract: A 48-year old man presented with chest pain and haemoptysis. Chest computed tomography showed a 60-mm mass in the left upper lobe of the lung, adjacent to the distal aortic arch. Bronchoscopic cytology revealed the presence of malignant cells and, in the absence of evidence of distant metastasis, a thoracotomy was performed. Although the tumour was firmly adherent to the distal aortic arch, under temporary bypass from the left subclavian artery to the descending aorta, it was successfully resected en bloc with the section of the aorta attached to it. The tumour was diagnosed as a primary synovial sarcoma of the lung on the basis of histopathological findings and fluorescent chromogenic in situ hybridization, showing SS18 gene rearrangement.
authors.affiliation: Department of General Thoracic Surgery, Tsukuba Medical Center Hospital, Ibaraki, Japan. ichimura@tmch.or.jp
authors.forename: Hideo
authors.initials: H
authors.lastname: Ichimura
authors.forename: Shinji
authors.initials: S
authors.lastname: Kikuchi
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Ozawa
authors.forename: Kanji
authors.initials: K
authors.lastname: Matsuzaki
mesh_terms: D001013:Aorta, Thoracic / Q000473:pathology / Q000601:surgery; D001999:Bronchoscopy; D015321:Gene Rearrangement; D006801:Humans; D017403:In Situ Hybridization; D008175:Lung Neoplasms / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011013:Pneumonectomy / Q000379:methods*; D011518:Proto-Oncogene Proteins / Q000235:genetics; D012097:Repressor Proteins / Q000235:genetics; D013584:Sarcoma, Synovial / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D013908:Thoracotomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D011518:Proto-Oncogene Proteins; D012097:Repressor Proteins; C093961:SS18 protein, human
keywords: Aorta; Lung resection; Synovial sarcoma; Temporary bypass