title: [Study on optimal processing technology of three kinds of processed coptidis rhizoma].
abstract: OBJECTIVE
  To optimize the processing technology of Coptidis Rhizoma and study the effects of different adjuvants on alkaloids during processing.
  
  
  METHODS
  The moistening time of adjuvants (A), processing temperature (B) and processing time (C) were investigated by using the single factor test method and L9 (3(4)) orthogonal experiment design with the contents of four alkaloids as indexes.
  
  
  RESULTS
  The sequence of importance of the factors that affect the wine processed Coptidis Rhizoma (WC) was C > B > A, turmeric processed Coptidis Rhizoma (TC) and dogwood processed Coptidis Rhizoma (DC) was B > A > C.
  
  
  CONCLUSIONS
  The optimal processing technology of WC, TC and DC are drying for 4 h at 130 degrees C after moistening for 90 min, drying for 3 h at 100 degrees C after moistening for 60 min and drying for 2 h at 160 degrees C after moistening for 90 min, respectively.
authors.affiliation: College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China. wangdezhen88@163.com
authors.forename: De-Zhen
authors.initials: DZ
authors.lastname: Wang
authors.forename: Jun
authors.initials: J
authors.lastname: Yi
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Qian
authors.initials: Q
authors.lastname: Gao
authors.forename: Yan-Zhi
authors.initials: YZ
authors.lastname: Wang
authors.forename: Xue-Gang
authors.initials: XG
authors.lastname: Li
mesh_terms: D000470:Alkaloids / Q000032:analysis*; D001599:Berberine / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D039323:Coptis / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification*; D032086:Evodia / Q000737:chemistry; D005079:Excipients / Q000737:chemistry; D005638:Fruit / Q000737:chemistry; D006358:Hot Temperature; D027343:Rhizome / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D013997:Time Factors; D014920:Wine; D030521:Zingiberaceae / Q000737:chemistry
chemical_list: D000470:Alkaloids; D004365:Drugs, Chinese Herbal; D005079:Excipients; D001599:Berberine