title: Reactive oxygen species and antioxidant defense mechanisms in the oral cavity: a literature review.
abstract: Through dental procedures and environment, periodontal tissues are exposed to many types of reactive oxygen species (ROS). Recently, various forms of antioxidants have been introduced as an approach to fight dental diseases and improve general gingival health. This article focuses on the classification of antioxidants and the link between oxidative stress and periodontal disease. The protective mechanisms of antioxidants and how routine dental procedures may increase ROS is discussed. The final section reviews the effect of tobacco products on gingival health and disease.
authors.affiliation: Biomedical Sciences, Baylor College of Dentistry, Texas A and M Health Science Center, Baylor College of Dentistry, Dallas, TX, USA.
authors.forename: Symone M
authors.initials: SM
authors.lastname: San Miguel
authors.forename: Lynne A
authors.initials: LA
authors.lastname: Opperman
authors.forename: Edward P
authors.initials: EP
authors.lastname: Allen
authors.forename: Kathy K H
authors.initials: KK
authors.lastname: Svoboda
mesh_terms: D000975:Antioxidants / Q000145:classification / Q000494:pharmacology*; D003764:Dental Materials / Q000009:adverse effects; D006801:Humans; D009538:Nicotine / Q000633:toxicity; D018384:Oxidative Stress; D010510:Periodontal Diseases / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000145:classification / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D003764:Dental Materials; D017382:Reactive Oxygen Species; D009538:Nicotine