title: 18FDG PET-CT for detecting gastric cancer recurrence after surgical resection: a meta-analysis.
abstract: BACKGROUND
  We performed a meta-analysis to evaluate the value of (18)FDG PET-CT for the detection of gastric cancer recurrence after surgical resection.
  
  
  METHODS
  A systematic literature search was performed in the MEDLINE and EMBASE databases. We calculated the sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio for (18)FDG PET-CT. We also constructed summary receiver operating characteristic curves for (18)FDG PET-CT.
  
  
  RESULTS
  Eight studies (500 patients) were included. The sensitivity, specificity, positive likelihood ratio and negative likelihood ratio of (18)FDG PET-CT were 0.86 (95% confidence interval [CI] = 0.71-0.94), 0.88 (95% CI = 0.75-0.94), 17.0 (95% CI = 3.5-14.0), and 0.16 (95% CI = 0.07-0.34), respectively. Overall weighted area under the curve was 0.93 (95% CI = 0.91-0.95).
  
  
  CONCLUSIONS
  (18)FDG PET-CT has moderate sensitivity and specificity for detection of gastric cancer recurrence after surgical resection.
authors.affiliation: Department of Medicine, Tumor Hospital Affiliated to Zhengzhou University, Dongming Road, Zhengzhou 450000, China.
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Zou
authors.forename: Yanqiu
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D006801:Humans; D019788:Fluorodeoxyglucose F18; D008175:Lung Neoplasms / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D049268:Positron-Emission Tomography; D011183:Postoperative Complications; D011379:Prognosis; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18; D019275:Radiopharmaceuticals
keywords: Gastric cancer; Meta-analysis; PET-CT; Recurrence