title: Fatal influenza A(H1N1)pdm09 encephalopathy in immunocompetent man.
abstract: We report an immunocompetent patient who had fatal encephalopathy after mild influenza. He rapidly died after unusual symptoms related to intracerebral thrombosis and hemorrhage. A brain biopsy specimen was positive for influenza A(H1N1)pdm09 virus RNA, but a lung biopsy specimen and cerebrospinal spinal fluid samples were negative.
authors.affiliation: Hospices Civils de Lyon, Lyon, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Simon
authors.forename: Romain
authors.initials: R
authors.lastname: Hernu
authors.forename: Martin
authors.initials: M
authors.lastname: Cour
authors.forename: Jean-Sébastien
authors.initials: JS
authors.lastname: Casalegno
authors.forename: Bruno
authors.initials: B
authors.lastname: Lina
authors.forename: Laurent
authors.initials: L
authors.lastname: Argaud
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics; D007251:Influenza, Human / Q000150:complications* / Q000276:immunology; D008297:Male; D014057:Tomography, X-Ray Computed
keywords: adult; cerebral venous thrombosis; encephalitis; encephalopathy; influenza; influenza A(H1N1)pdm09; influenza virus; neurologic complication; seizure; viruses