title: Status epilepticus.
abstract: OBJECTIVE
  This review presents the state of the art in the diagnosis and management of status epilepticus.
  
  
  RESULTS
  In addition to general background, this article presents the most recent findings regarding the diagnosis and treatment of status epilepticus, including the results of the Rapid Anticonvulsant Medication Prior to Arrival Trial (RAMPART) and the available data on the use of newer antiepileptic and anesthetic drugs in the treatment of refractory status epilepticus. It also presents available guidelines such as those from the Neurocritical Care Society.
  
  
  CONCLUSIONS
  Despite recent advances, the management of status epilepticus remains a challenge. Rapid treatment, a written treatment protocol, early consideration of nonconvulsive seizures, and avoiding overtreatment and medical complications are the keys to successful management. This article summarizes the current evidence and guidelines.
authors.affiliation: Yale University School of Medicine, 15 York St, LLCI-714, New Haven, CT 06510, USA. lawrence.hirsch@yale.edu
authors.forename: Lawrence J
authors.initials: LJ
authors.lastname: Hirsch
authors.forename: Nicolas
authors.initials: N
authors.lastname: Gaspard
mesh_terms: D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D013226:Status Epilepticus / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D055815:Young Adult