title: Solid variant of papillary thyroid carcinoma in a 14-year-old girl.
abstract: Solid variant of papillary thyroid carcinoma (PTC) is a rare, poorly characterised variant and predominantly reported in children with a history of radiation exposure. This variant has a high propensity for extra-thyroidal extension and cervical lymph node metastases. A 14-year-old Malay girl who had no history of radiation exposure, presented with multiple cervical lymphadenopathy and it was clinically suspicious for tuberculosis or lymphoma. An incisional biopsy revealed a metastatic PTC. The patient underwent total thyroidectomy with bilateral lateral neck dissection and histopathology report was solid variant of PTC. Whole-body I(131) scan was performed which revealed an intense tracer uptake in the neck. She was planned for radioactive iodine ablation and now on regular follow-up for monitoring of possible tumour metastasis.
authors.affiliation: Department of Pathology, Universiti Sains Malaysia, KotaBharu, Kelantan, Malaysia. wfaiziah@kb.usm.my
authors.forename: Wan Faiziah Wan
authors.initials: WF
authors.lastname: Abdul Rahman
authors.forename: Mohd Nizam
authors.initials: MN
authors.lastname: Md Hashim
authors.forename: Thin Thin
authors.initials: TT
authors.lastname: Win
authors.forename: Ikmal Hisyam
authors.initials: IH
authors.lastname: Bakrin
mesh_terms: D000293:Adolescent; D002277:Carcinoma / Q000175:diagnosis* / Q000473:pathology; D002291:Carcinoma, Papillary; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008206:Lymphatic Diseases / Q000175:diagnosis; D009333:Neck; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology