title: Virus maturation.
abstract: The formation of infectious virus particles is a highly complex process involving a series of sophisticated molecular events. In most cases, the assembly of virus structural elements results in the formation of immature virus particles unable to initiate a productive infection. Accordingly, for most viruses the final stage of the assembly pathway entails a set of structural transitions and/or biochemical modifications that transform inert precursor particles into fully infectious agents. In this chapter, we review the most relevant maturation mechanisms involved in the generation of infectious virions for a wide variety of viruses.
authors.affiliation: Laboratorio de Biología Celular y Molecular, Instituto de Histología y Embriología Mendoza (IHEM), Facultad de Ciencias Médicas, Instituto de Ciencias Básicas, Universidad Nacional de Cuyo, Mendoza, Argentina.
authors.forename: Laura R
authors.initials: LR
authors.lastname: Delgui
authors.forename: José F
authors.initials: JF
authors.lastname: Rodríguez
mesh_terms: D000818:Animals; D006801:Humans; D014771:Virion / Q000502:physiology*; D019065:Virus Assembly; D014780:Viruses / Q000378:metabolism*