title: Antioxidant activity of different parts of Tetrataenium lasiopetalum.
abstract: BACKGROUND
  In Iranian traditional medicine, different species of the genus Tetrataenium are used as antiseptic, spice and food additives.
  
  
  OBJECTIVE
  The present study examined the possible antioxidant effects of hydro-alcoholic extracts of different parts of Tetrataenium lasiopetalum (Boiss.) Manden (Apiaceae).
  
  
  METHODS
  Laminas, stems, petioles, fruits, peduncles and flowers of T. lasiopetalum were collected, dried and then extracted by ethanol and water (70:30). Antioxidant activities of extracts were examined by employing different in vitro assays, i.e., 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, metal chelating, reducing power activities and hemoglobin-induced linoleic acid system. Also, total phenolic and flavonoid contents of the extracts were evaluated.
  
  
  RESULTS
  Hydro-alcoholic extract of T. lasiopetalum flower showed the highest activity in scavenging of DPPH (IC50 = 170 ± 7 μg/mL). In metal chelating assay, lamina extract possesses a better iron ion chelating activity than other extracts (230 ± 10 μg/mL). Lamina hydro-alcoholic extract demonstrated better activity in reducing the power and hemoglobin-induced linoleic acid system than other parts of T. lasiopetalum.
  
  
  CONCLUSIONS
  These results showed the antioxidant activity of different parts of T. lasiopetalum based on its usage in traditional medicine.
authors.affiliation: Department of Biology, Faculty of Science, Boroujerd Branch, Islamic Azad University, Boroujerd, Iran.
authors.forename: Mohammad Mehdi
authors.initials: MM
authors.lastname: Dehshiri
authors.forename: Hossein
authors.initials: H
authors.lastname: Aghamollaei
authors.forename: Mehdi
authors.initials: M
authors.lastname: Zarini
authors.forename: Seyed Mohammad
authors.initials: SM
authors.lastname: Nabavi
authors.forename: Morteza
authors.initials: M
authors.lastname: Mirzaei
authors.forename: Monica Rosa
authors.initials: MR
authors.lastname: Loizzo
authors.forename: Seyed Fazel
authors.initials: SF
authors.lastname: Nabavi
mesh_terms: D000975:Antioxidants / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D019661:Apiaceae / Q000737:chemistry*; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D007492:Iran; D007502:Iron Chelating Agents / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology; D008519:Medicine, Traditional; D010636:Phenols / Q000302:isolation & purification / Q000494:pharmacology; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D012997:Solvents / Q000737:chemistry
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D016166:Free Radical Scavengers; D007502:Iron Chelating Agents; D010636:Phenols; D010936:Plant Extracts; D012997:Solvents