title: Advances in zirconia toughened alumina biomaterials for total joint replacement.
abstract: The objective of this article is to provide an up-to-date overview of zirconia-toughened alumina (ZTA) components used in total hip arthroplasties. The structure, mechanical properties, and available data regarding the clinical performance of ZTA are summarized. The advancements that have been made in understanding the in vivo performance of ZTA are investigated. This article concludes with a discussion of gaps in the literature related to ceramic biomaterials and avenues for future research.
authors.affiliation: Exponent, Inc., Philadelphia, PA, United States; Drexel University, Philadelphia, PA, United States. Electronic address: skurtz@exponent.com.
authors.forename: Steven M
authors.initials: SM
authors.lastname: Kurtz
authors.affiliation: Drexel University, Philadelphia, PA, United States.
authors.forename: Sevi
authors.initials: S
authors.lastname: Kocagöz
authors.affiliation: Drexel University, Philadelphia, PA, United States.
authors.forename: Christina
authors.initials: C
authors.lastname: Arnholt
authors.affiliation: Exponent, Inc., Menlo Park, CA, United States.
authors.forename: Roland
authors.initials: R
authors.lastname: Huet
authors.affiliation: Kyocera Medical, Osaka, Japan.
authors.forename: Masaru
authors.initials: M
authors.lastname: Ueno
authors.affiliation: Specialist Orthopaedic Group, Wollstonecraft, NSW, Australia.
authors.forename: William L
authors.initials: WL
authors.lastname: Walter
mesh_terms: D000537:Aluminum Oxide / Q000138:chemical synthesis*; D001672:Biocompatible Materials / Q000138:chemical synthesis*; D002516:Ceramics / Q000138:chemical synthesis*; D055119:Elastic Modulus; D005544:Forecasting; D006244:Hardness; D006622:Hip Prosthesis / Q000639:trends*; D011474:Prosthesis Design / Q000639:trends; D015040:Zirconium / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D015040:Zirconium; D000537:Aluminum Oxide; C028541:zirconium oxide
keywords: Alumina; Oxidized zirconium; Phase transformation; Properties; Structure; Total hip arthroplasty; Zirconia; Zirconia toughened alumina (ZTA)