title: Diagnostic and therapeutic role of endoscopy in gastroenteropancreatic neuroendocrine neoplasms.
abstract: Gastroenteropancreatic neuroendocrine neoplasms have substantially increased over the last decades. Because of the indolent clinical course of the disease even in advance stages and the rise in the incidental diagnosis of small asymptomatic lesions, the prevalence of gastroenteropancreatic neuroendocrine neoplasms is higher than that of pancreatic, gastric and oesophageal adenocarcinomas, making them the second most prevalent cancer type of the gastrointestinal tract. This increase in the overall prevalence of gastroenteropancreatic neuroendocrine neoplasms has been paralleled by a growth in the importance of the endoscopist in the care of these patients, who usually require a multidisciplinary approach. In this manuscript the diagnostic and therapeutic role of endoscopic for gastroenteropancreatic neuroendocrine neoplasms will be reviewed.
authors.affiliation: Digestive Endoscopy Unit, Catholic University, Rome, Italy.
authors.forename: Fabia
authors.initials: F
authors.lastname: Attili
authors.affiliation: Division of Digestive and Liver Disease, University La Sapienza, Rome, Italy.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Capurso
authors.affiliation: Digestive Endoscopy Unit, Catholic University, Rome, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Vanella
authors.affiliation: Division of Gastroenterology, S. Orsola-Malpighi Hospital, University of Bologna, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Fuccio
authors.affiliation: Division of Digestive and Liver Disease, University La Sapienza, Rome, Italy.
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Delle Fave
authors.affiliation: Digestive Endoscopy Unit, Catholic University, Rome, Italy.
authors.forename: Guido
authors.initials: G
authors.lastname: Costamagna
authors.affiliation: Digestive Endoscopy Unit, Catholic University, Rome, Italy. Electronic address: albertolarghi@yahoo.it.
authors.forename: Alberto
authors.initials: A
authors.lastname: Larghi
mesh_terms: D004379:Duodenal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D016145:Endoscopy, Digestive System; D006801:Humans; D007414:Intestinal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D018358:Neuroendocrine Tumors / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery
keywords: Diagnosis; Endoscopic ultrasound; Endoscopy; Gastroenteropancreatic neuroendocrine neoplasms; Therapy