title: Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: lessons learned from first clinical trials.
abstract: The Fourth Expert Meeting of the Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Consortium took place in Barcelona on October 19 and 20, 2012. This meeting focused on the translation of preclinical data into early clinical settings. This position paper highlights the main topics explored on the safety and efficacy of mesenchymal stem cells as a therapeutic agent in solid organ transplantation and emphasizes the issues (proper timing, concomitant immunossupression, source and immunogenicity of mesenchymal stem cells, and oncogenicity) that have been addressed and will be followed up by the MiSOT Consortium in future studies.
authors.affiliation: Transplantation and Nephrology, Erasmus MC, Rotterdam, The Netherlands. m.franquesa@erasmusmc.nl
authors.forename: Marcella
authors.initials: M
authors.lastname: Franquesa
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Hoogduijn
authors.forename: Marlies E
authors.initials: ME
authors.lastname: Reinders
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authors.lastname: Eggenhofer
authors.forename: Anja U
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authors.lastname: Engela
authors.forename: Fane K
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authors.lastname: Mensah
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authors.lastname: Torras
authors.forename: Antonello
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authors.lastname: Pileggi
authors.forename: Cees
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authors.lastname: van Kooten
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authors.lastname: Mahon
authors.forename: Oliver
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authors.lastname: Detry
authors.forename: Felix C
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authors.lastname: Popp
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authors.lastname: Benseler
authors.forename: Federica
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authors.lastname: Casiraghi
authors.forename: Christian
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authors.lastname: Johnson
authors.forename: Janis
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authors.lastname: Ancans
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authors.lastname: Fillenberg
authors.forename: Olga
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authors.lastname: delaRosa
authors.forename: Josep M
authors.initials: JM
authors.lastname: Aran
authors.forename: Marieke
authors.initials: M
authors.lastname: Roemeling-van Rhijn
authors.forename: Marieke
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authors.lastname: Roemeling-vanRhijn
authors.forename: Jef
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authors.lastname: Pinxteren
authors.forename: Norberto
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authors.lastname: Perico
authors.forename: Eliana
authors.initials: E
authors.lastname: Gotti
authors.forename: Bruno
authors.initials: B
authors.lastname: Christ
authors.forename: James
authors.initials: J
authors.lastname: Reading
authors.forename: Martino
authors.initials: M
authors.lastname: Introna
authors.forename: Robert
authors.initials: R
authors.lastname: Deans
authors.forename: Murat
authors.initials: M
authors.lastname: Shagidulin
authors.forename: Ramon
authors.initials: R
authors.lastname: Farré
authors.forename: Alessandro
authors.initials: A
authors.lastname: Rambaldi
authors.forename: Albert
authors.initials: A
authors.lastname: Sanchez-Fueyo
authors.forename: Natasha
authors.initials: N
authors.lastname: Obermajer
authors.forename: Andrey
authors.initials: A
authors.lastname: Pulin
authors.forename: Frank J M F
authors.initials: FJ
authors.lastname: Dor
authors.forename: Isabel
authors.initials: I
authors.lastname: Portero-Sanchez
authors.forename: Carla C
authors.initials: CC
authors.lastname: Baan
authors.forename: Ton J
authors.initials: TJ
authors.lastname: Rabelink
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Remuzzi
authors.forename: Michiel G H
authors.initials: MG
authors.lastname: Betjes
authors.forename: Marc H
authors.initials: MH
authors.lastname: Dahlke
authors.forename: Josep M
authors.initials: JM
authors.lastname: Grinyó
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation / Q000009:adverse effects / Q000331:legislation & jurisprudence