title: Synthesis of paclitaxel-conjugated β-cyclodextrin polyrotaxane and its antitumor activity.
authors.affiliation: Laboratory of Mesoscopic Chemistry and Department of Polymer Science & Engineering, College of Chemistry & Chemical Engineering, Nanjing University, Nanjing, 210093, P. R. China.
authors.forename: Shuling
authors.initials: S
authors.lastname: Yu
authors.forename: Yajun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Xu
authors.initials: X
authors.lastname: Zhen
authors.forename: Zhaoheng
authors.initials: Z
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Wu
authors.forename: Xiqun
authors.initials: X
authors.lastname: Jiang
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000737:chemistry* / Q000493:pharmacokinetics; D045744:Cell Line, Tumor; D003505:Cyclodextrins / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry*; D006207:Half-Life; D008113:Liver Neoplasms / Q000188:drug therapy; D051379:Mice; D017239:Paclitaxel / Q000008:administration & dosage / Q000737:chemistry*; D020442:Poloxamer / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D011409:Propylene Glycols / Q000737:chemistry; D043862:Rotaxanes / Q000737:chemistry*; D014018:Tissue Distribution; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D003505:Cyclodextrins; D004337:Drug Carriers; D011108:Polymers; D011409:Propylene Glycols; D043862:Rotaxanes; D047392:beta-Cyclodextrins; C475673:polyrotaxane; D020442:Poloxamer; C012504:polypropylene glycol; C031215:betadex; D017239:Paclitaxel
keywords: antitumor agents; biodistribution; paclitaxel; polyrotaxanes; β-cyclodextrin