title: [Gonococci change more quickly than prescribing practices; resistance to frequently prescribed antibiotics].
abstract: Gonococcal resistance to antibiotics is increasing worldwide. In patients tested in Dutch STI clinics in 2009, gonococcal resistance to ciprofloxacin was over 50%. Ceftriaxone, a third-generation cephalosporin, has been the first-choice medication since 2004. General practitioners treated 25% of their gonorrhoea patients with ciprofloxacin in 2010. There is a need for up-to-the-minute, dynamic guidelines for treating gonorrhoea as well as the more systematic use of an up-to-date digital prescription system.
authors.affiliation: Rijksinstituut voor Volksgezondheid en Milieu, Centrum Infectieziektebestrijding, Bilthoven, the Netherlands. femke.koedijk@rivm.nl
authors.forename: Femke D H
authors.initials: FD
authors.lastname: Koedijk
authors.forename: Ingrid  V F
authors.initials: I
authors.lastname: van den Broek
authors.forename: Irina
authors.initials: I
authors.lastname: Stirbu-Wagner
authors.forename: Jan E A M
authors.initials: JE
authors.lastname: van Bergen
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D002443:Ceftriaxone / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D006069:Gonorrhea / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D009344:Neisseria gonorrhoeae / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D002443:Ceftriaxone