title: Combating of scorpion bite with Pakistani medicinal plants having ethno-botanical evidences as antidote.
abstract: Although the majority of serious cases in the world are concerned with snake bite envenomation, but those which are caused by scorpion stings are also famous for causing extreme pain. The present view is an attempt to enlist scientifically ignored medicinal plants of Pakistan exhibiting anti-scorpion venom activity. In this review data of 35 medicinal plants is collected with their families, parts used, distribution in Pakistan, and major constituents present in plant. Amaranthaceae, Astraceae and Euphorbiaceae represent 3 species. Anacardiaceae, Asclepidaceae and Liliaceae represent 2 species. Araceae, Capparidaceae, Ceasalpinaceae, Cyperaceae, Labiatae, Lamiaceae, Meliaceae, Menispermaceae, Oleaceae, Oxalidaceae, Pinaceae, Polygonaceae, Rhamnaceae, Rubiaceae, Solanaceae, Valerianaceae and Zingiberaceae represented single medicinal plant with anti scorpion potential. According to literature, all parts are used in anti scorpion envenomination. Leaves exhibit 30%, whole plant 9%, fruit, bark and seeds 8% anti scorpion activity. Bulb and stems show 5% contribution in this respect and twigs, resins, inflorescence, latex and flowers express 3% potential. This article may assist the researchers to bring innovation in natural product field for scorpion bite envenomation. However, these medicinal plants are still requiring pharmacological and phytochemical investigation in order to be claimed as effective in scorpion bite envenomation.
authors.affiliation: Department of Pharmacy, COMSATS Institute of Information and Technology, Abbottabad 22060, Pakistan.
authors.forename: Muhammad Jawad
authors.initials: MJ
authors.lastname: Nasim
authors.forename: Muhammad Hassham Hassan Bin
authors.initials: MH
authors.lastname: Asad
authors.forename: Ashif
authors.initials: A
authors.lastname: Sajjad
authors.forename: Shujaat Ali
authors.initials: SA
authors.lastname: Khan
authors.forename: Amara
authors.initials: A
authors.lastname: Mumtaz
authors.forename: Kalsoom
authors.initials: K
authors.lastname: Farzana
authors.forename: Zarmina
authors.initials: Z
authors.lastname: Rashid
authors.forename: Ghulam
authors.initials: G
authors.lastname: Murtaza
mesh_terms: D000818:Animals; D000931:Antidotes / Q000627:therapeutic use*; D001733:Bites and Stings / Q000188:drug therapy*; D019448:Ethnobotany; D006801:Humans; D010154:Pakistan; D008517:Phytotherapy; D010946:Plants, Medicinal; D012605:Scorpions
chemical_list: D000931:Antidotes