title: Motivators to participation in actual HIV vaccine trials.
abstract: An examination of actual HIV vaccine trials can contribute to an understanding of motivators for participation in these studies. Analysis of these motivators reveals that they can be categorized as social and personal benefits. Social benefits are generally altruistic, whereas personal benefits are psychological, physical, and financial. In this systematic review, the authors performed a literature search for actual preventive HIV vaccine trials reporting motivators to participation. Of studies conducted in the Organization for Economic Co-operation and Development (OECD) countries, the authors retrieved 12 studies reporting on social benefits and seven reporting on personal benefits. From the non-OECD countries, nine studies reported on social benefits and eight studies on personal benefits. Social benefits were most frequently described on macroscopic, altruistic levels. Personal benefits were most frequently psychological in nature. Rates of participation were compared between the OECD and the non-OECD countries. Knowledge of actual motivators in specific countries and regions can help target recruitment in various types of actual HIV vaccine trials.
authors.affiliation: University of British Columbia, 2329 West Mall, Vancouver, BC, V6T 1Z4, Canada, shayestadhalla@yahoo.com.
authors.forename: Shayesta
authors.initials: S
authors.lastname: Dhalla
authors.forename: Gary
authors.initials: G
authors.lastname: Poole
mesh_terms: D016915:AIDS Vaccines / Q000008:administration & dosage*; D002986:Clinical Trials as Topic / Q000523:psychology*; D005260:Female; D015658:HIV Infections / Q000517:prevention & control* / Q000523:psychology; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D009042:Motivation; D010349:Patient Compliance; D010358:Patient Participation / Q000523:psychology*
chemical_list: D016915:AIDS Vaccines