title: Percutaneous vertebral augmentation for painful osteolytic vertebral metastasis: a case report.
abstract: BACKGROUND
  Vertebral metastases are associated with significant pain, disability, and morbidity. Open surgery for fracture stabilization is often inappropriate in this population due to a poor risk-benefit profile, particularly if life expectancy is short. Percutaneous vertebroplasty and kyphoplasty are appealing adjunctive procedures in patients with malignancy for alleviation of intractable pain. However, these patients have higher risk of serious complications, notably cement extravasation. Described in this report is a case of a painful osteolytic vertebral metastasis that was successfully treated by a novel percutaneous vertebral augmentation system.
  
  
  METHODS
  A 42-year-old Caucasian female presented with a history of metastatic lung cancer unresponsive to radiation and chemotherapy with symptoms inadequately controlled by opiates over the previous 6 months. Magnetic resonance imaging and spiral computed tomography with two-dimensional reconstruction showed an osteolytic vertebral metastasis with complete involvement of the T10 vertebral body, extending to the cortical vertebral wall anteriorly and posteriorly. The patient was treated with percutaneous vertebral augmentation (Kiva® VCF Treatment System, Benvenue Medical, Inc, Santa Clara, CA) utilizing a novel coil-shaped polyetheretherketone implant designed to minimize the risk of cement extravasation. After the minimally invasive procedure, bone cement distribution within the vertebral body was ideal, with no observed cement extravasation. No complications were reported, pain completely resolved within 24 hours, and use of intravenous narcotics was progressively diminished within 1 week. Complete pain relief was maintained throughout 4 months of follow-up.
  
  
  CONCLUSIONS
  The Kiva System represents a novel and effective minimally invasive treatment option for patients suffering from severe pain due to osteolytic vertebral metastasis.
authors.affiliation: Institute for Cancer Research and Treatment, Turin, Italy.
authors.forename: Giovanni C
authors.initials: GC
authors.lastname: Anselmetti
authors.forename: Sean M
authors.initials: SM
authors.lastname: Tutton
authors.forename: Francis R
authors.initials: FR
authors.lastname: Facchini
authors.forename: Larry E
authors.initials: LE
authors.lastname: Miller
authors.forename: Jon E
authors.initials: JE
authors.lastname: Block
keywords: Kiva; minimally invasive; pain