title: [Cohort study of 684 pairs of mother-and-child allergic diseases].
abstract: OBJECTIVE
  To understand allergic diseases related factors in Changzheng Town, Putuo District infants and young children.
  
  
  METHODS
  Pregnant women registered in Putuo District, Changzheng Town Community Health Service Center Child Health Clinic within the period from January to December, 2008 were enrolled into this survey, a questionnaire survey. The infants were followed up from birth to 2 years of age. The mother and child survey was conducted for 746 pairs, and 684 pairs had complete data. SAS V9.1 statistical software was used for data processing and statistical analysis.
  
  
  RESULTS
  The survey showed that prevalence of eczema, allergic rash, and wheezing was 27.9%, 18.9%, and 3.9%, respectively. Multivariate logistic regression analysis showed that allergy in either parent and addition of foods other than milk in infants before 4 months of age were risk factors for eczema; allergy in either parent was also risk factors for allergic rash. Exclusive breastfeeding from birth to 6 months of age was a protective factor for wheezing in infants. Other factors such as parental history of asthma, vitamin supplements to the mothers during pregnancy, mothers' special diet habits, calcium level of infants, etc. had no significant correlation with allergic disorders in infants.
  
  
  CONCLUSIONS
  The risk factors for allergic disorders in infants included allergy in either parent and dietary factors of the infants themselves (prematurely adding other foods). Breastfeeding (for 0 - 6 months of age) was a protective factor for infants' wheezing.
authors.affiliation: Changzheng Town, Putuo District Community Health Service Center, Shanghai 200333, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Huang
authors.forename: Feng-ying
authors.initials: FY
authors.lastname: Zhang
authors.forename: Jing-qing
authors.initials: JQ
authors.lastname: Hang
authors.forename: Jie
authors.initials: J
authors.lastname: Zhu
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.forename: Pei-feng
authors.initials: PF
authors.lastname: Chen
authors.forename: Wei-lian
authors.initials: WL
authors.lastname: Gu
mesh_terms: D000328:Adult; D001249:Asthma / Q000453:epidemiology* / Q000209:etiology* / Q000235:genetics; D001942:Breast Feeding; D015331:Cohort Studies; D004485:Eczema / Q000453:epidemiology* / Q000209:etiology* / Q000235:genetics; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications* / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D016015:Logistic Models; D008297:Male; D015999:Multivariate Analysis; D010290:Parents; D011247:Pregnancy; D012307:Risk Factors; D011795:Surveys and Questionnaires