title: Postmortem high-resolution fetal magnetic resonance imaging in three cases of lower urinary tract obstruction.
abstract: In this manuscript we report 3 cases of severe lower urinary tract obstruction diagnosed before 20 weeks of pregnancy. All cases had a very similar prenatal presentation with a megacystis, bilateral hydro-ureteronephrosis and increased echogenicity of the kidneys. High-resolution postmortem magnetic resonance imaging (MRI), following termination of pregnancy, enabled accurate investigation of the underlying cause of the urinary tract obstruction, by depicting the presence of an urethral valve, urethral atresia and cloacal dysgenesis. Postmortem fetal MRI provides high anatomical detail and is very suitable to investigate congenital anomalies of the lower urinary tract. In case (timely or consented) conventional autopsy is not possible, MRI is an excellent alternative.
authors.affiliation: Department of Radiology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Lefere
authors.forename: Inga
authors.initials: I
authors.lastname: Sandaite
authors.forename: An
authors.initials: A
authors.lastname: Hindryckx
authors.forename: Roland
authors.initials: R
authors.lastname: Devlieger
authors.forename: Luc
authors.initials: L
authors.lastname: De Catte
authors.forename: Philippe
authors.initials: P
authors.lastname: Moerman
authors.forename: Filip
authors.initials: F
authors.lastname: Claus
mesh_terms: D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D011296:Prenatal Diagnosis; D014524:Urethral Obstruction / Q000473:pathology*; D014551:Urinary Tract / Q000002:abnormalities / Q000473:pathology