title: Oncocytic carcinoid tumor of the lung with intense F-18 fluorodeoxyglucose (FDG) uptake in positron emission tomography-computed tomography (PET/CT).
abstract: The present report describes a case of typical carcinoid tumor with intense fluorodeoxyglucose (FDG) uptake. The most of tumor cells were characterized by eosinophilic cytoplasm resulting from accumulation of mitochondria, which was called an oncocytic carcinoid tumor. Glucose transporter type 1 (GLUT-1) was expressed in a membranous pattern in the oncocytic component. Oncocytic carcinoid tumors could show intense FDG uptake due to the numerous intracellular mitochondria and the membranous overexpression of GLUT-1. Thus, it could be a potential pitfall of interpreting FDG-PET/CT image.
authors.affiliation: Department of Diagnostic Radiology, National Hospital Organization, Shikoku Cancer Center, Kou-160 Minamiumemoto-machi, Matsuyama, Ehime, 791-0280, Japan, yuki.tanabe.0225@gmail.com.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Tanabe
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Sugawara
authors.forename: Rieko
authors.initials: R
authors.lastname: Nishimura
authors.forename: Kohei
authors.initials: K
authors.lastname: Hosokawa
authors.forename: Makoto
authors.initials: M
authors.lastname: Kajihara
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Shimizu
authors.forename: Tadaaki
authors.initials: T
authors.lastname: Takahashi
authors.forename: Shinya
authors.initials: S
authors.lastname: Sakai
authors.forename: Shigeki
authors.initials: S
authors.lastname: Sawada
authors.forename: Motohiro
authors.initials: M
authors.lastname: Yamashita
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Ohtani
mesh_terms: D000368:Aged; D001692:Biological Transport; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging* / Q000378:metabolism; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D008297:Male; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18