title: Triplex-Inspector: an analysis tool for triplex-mediated targeting of genomic loci.
abstract: CONCLUSIONS
  At the heart of many modern biotechnological and therapeutic applications lies the need to target specific genomic loci with pinpoint accuracy. Although landmark experiments demonstrate technological maturity in manufacturing and delivering genetic material, the genomic sequence analysis to find suitable targets lags behind. We provide a computational aid for the sophisticated design of sequence-specific ligands and selection of appropriate targets, taking gene location and genomic architecture into account.
  
  
  BACKGROUND
  Source code and binaries are downloadable from www.bioinformatics.org.au/triplexator/inspector.
  
  
  BACKGROUND
  t.bailey@uq.edu.au
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Division of Genomics and Computational Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia.
authors.forename: Fabian A
authors.initials: FA
authors.lastname: Buske
authors.forename: Denis C
authors.initials: DC
authors.lastname: Bauer
authors.forename: John S
authors.initials: JS
authors.lastname: Mattick
authors.forename: Timothy L
authors.initials: TL
authors.lastname: Bailey
mesh_terms: D004247:DNA / Q000737:chemistry*; D018390:Gene Targeting; D056426:Genetic Loci; D023281:Genomics; D006801:Humans; D020135:Peptide Nucleic Acids / Q000737:chemistry; D012984:Software
chemical_list: D020135:Peptide Nucleic Acids; C051802:triplex DNA; D004247:DNA