title: Laboratory testing for platelet antibodies.
abstract: Laboratory testing for immune-mediated thrombocytopenias involves identification and classification of antibodies present in patient sera or attached to patient platelets. This article summarizes the available types of platelet antibody testing and applications in disorders such as neonatal alloimmune thrombocytopenia, post-transfusion purpura, multiple platelet transfusion refractoriness, immune thrombocytopenia, and drug-induced thrombocytopenia.
authors.affiliation: Department of Pathology, University of Utah Health Sciences Center, and ARUP Laboratories Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA.
authors.forename: Nahla M
authors.initials: NM
authors.lastname: Heikal
authors.forename: Kristi J
authors.initials: KJ
authors.lastname: Smock
mesh_terms: D001323:Autoantibodies / Q000097:blood / Q000145:classification / Q000302:isolation & purification*; D001792:Blood Platelets / Q000276:immunology / Q000473:pathology; D006801:Humans; D007118:Immunoassay; D007231:Infant, Newborn; D017713:Platelet Transfusion; D011696:Purpura, Thrombocytopenic / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D011803:Quinine / Q000009:adverse effects; D013449:Sulfonamides / Q000009:adverse effects; D013921:Thrombocytopenia / Q000139:chemically induced / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D054098:Thrombocytopenia, Neonatal Alloimmune / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology
chemical_list: D001323:Autoantibodies; D013449:Sulfonamides; D011803:Quinine