title: Anatomic repair for corrected transposition with left ventricular outflow tract obstruction.
abstract: BACKGROUND
  We investigated the long-term outcomes of anatomic repair for congenitally corrected transposition of great arteries (ccTGA) and its variant associated with left ventricular outflow tract obstruction (LVOTO) and ventricular septal defect (VSD).
  
  
  METHODS
  From 1987 to 2011, 47 patients (27 with pulmonary atresia and 20 with pulmonary stenosis) with ccTGA and its variant associated with LVOTO and VSD underwent anatomic repair. The mean operative age was 5.5 ± 3.7 years old (range, 1.6 to 21.3). The preoperative right ventricular end-diastolic volume was 133% ± 31% (81 to 222) of their normal size. The atrial switch procedure was Mustard in 31 patients and Senning in 16, with the latter used in all from 2002.
  
  
  RESULTS
  The mean follow-up period was 11.6 ± 7.3 years (maximum, 22.7). The VSD was concomitantly enlarged in 4 patients and Damus-Kaye-Stansel (DKS) anastomosis was added in 9 patients with pulmonary stenosis and restrictive VSD. The overall survival rate at 20 years was 70.2% and no mortality has been observed in 21 consecutive patients since 1997. No patient required reoperation for the postoperative systemic ventricular outflow tract obstruction. A surgical heart block developed in 1 patient (2.1%) who underwent concomitant VSD enlargement. None of the patients developed a moderate or greater aortic or neo-aortic regurgitation.
  
  
  CONCLUSIONS
  Recent outcomes after anatomic repair for congenitally corrected transposition of great arteries associated with LVOTO and VSD were excellent. For patients with pulmonary stenosis and restrictive VSD, additional DKS anastomosis seems to be an effective approach to avoid postoperative systemic ventricular outflow tract obstruction and surgical heart block.
authors.affiliation: Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan. thoashi@surg1.med.osaka-u.ac.jp
authors.forename: Takaya
authors.initials: T
authors.lastname: Hoashi
authors.forename: Koji
authors.initials: K
authors.lastname: Kagisaki
authors.forename: Aya
authors.initials: A
authors.lastname: Miyazaki
authors.forename: Kenichi
authors.initials: K
authors.lastname: Kurosaki
authors.forename: Isao
authors.initials: I
authors.lastname: Shiraishi
authors.forename: Toshikatsu
authors.initials: T
authors.lastname: Yagihara
authors.forename: Hajime
authors.initials: H
authors.lastname: Ichikawa
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D000080041:Congenitally Corrected Transposition of the Great Arteries; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000150:complications* / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D011666:Pulmonary Valve Stenosis / Q000150:complications* / Q000601:surgery*; D012189:Retrospective Studies; D014188:Transposition of Great Vessels / Q000150:complications* / Q000601:surgery*; D014694:Ventricular Outflow Obstruction / Q000150:complications* / Q000601:surgery*; D055815:Young Adult
keywords: 20