title: Wearable system for non-invasive and continuous monitoring central aortic pressure curve and augmentation index.
abstract: The paper presents a non-invasive method and system for a long-term and continuous monitoring of the central aortic pressure (CAP) waveform and the augmentation index (AI). The CAP curve is estimated from the measured radial electrical bio-impedance (EBI) using spectral domain transfer functions (TF), which are established on the basis of data analysis during clinical experiments. Experiments were carried out on 3 volunteers by now. During the experiment, a 0.5 mg sublingual nitroglycerin tablet was administrated to each volunteer. Both, the reconstructed CAP curve and the AI have very good correlation with the results obtained by the SphygmoCor system. But, in opposite to the traditional tonometry based CAP curve and AI estimation methods, the proposed one is more convenient to use and allows continuous and long-term personalized monitoring of the CAP curve and of the AI.
authors.affiliation: Tallinn University of Technology, Estonia.
authors.forename: Andrei
authors.initials: A
authors.lastname: Krivoshei
authors.forename: Jürgen
authors.initials: J
authors.lastname: Lamp
authors.forename: Mart
authors.initials: M
authors.lastname: Min
authors.forename: Tiina
authors.initials: T
authors.lastname: Uuetoa
authors.forename: Hasso
authors.initials: H
authors.lastname: Uuetoa
authors.forename: Paul
authors.initials: P
authors.lastname: Annus
mesh_terms: D062186:Arterial Pressure; D001795:Blood Pressure Determination / Q000295:instrumentation*; D003936:Diagnosis, Computer-Assisted / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000503:physiopathology*; D008297:Male; D018670:Monitoring, Ambulatory / Q000295:instrumentation*; D010992:Plethysmography, Impedance / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D055815:Young Adult