title: WhichCyp: prediction of cytochromes P450 inhibition.
abstract: CONCLUSIONS
  In this work we present WhichCyp, a tool for prediction of which cytochromes P450 isoforms (among 1A2, 2C9, 2C19, 2D6 and 3A4) a given molecule is likely to inhibit. The models are built from experimental high-throughput data using support vector machines and molecular signatures.
  
  
  BACKGROUND
  The WhichCyp server is freely available for use on the web at http://drug.ku.dk/whichcyp, where the WhichCyp Java program and source code is also available for download.
authors.affiliation: Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, Copenhagen, Denmark.
authors.forename: Michal
authors.initials: M
authors.lastname: Rostkowski
authors.forename: Ola
authors.initials: O
authors.lastname: Spjuth
authors.forename: Patrik
authors.initials: P
authors.lastname: Rydberg
mesh_terms: D065607:Cytochrome P-450 Enzyme Inhibitors; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D020407:Internet; D007527:Isoenzymes / Q000037:antagonists & inhibitors; D012984:Software; D060388:Support Vector Machine
chemical_list: D065607:Cytochrome P-450 Enzyme Inhibitors; D004791:Enzyme Inhibitors; D007527:Isoenzymes