title: Liposomal doxorubicin plus radiofrequency ablation for complete necrosis of a hepatocellular carcinoma.
abstract: Radiofrequency ablation (rfa) is a standard treatment for small, unresectable hepatocellular carcinomas (hccs). However, rfa for larger tumours is less successful, and intravenous lyso-thermosensitive liposomal doxorubicin during rfa is one technique postulated to potentially address that limitation. This drug-plus-device combination therapy was used to completely treat a hcc in a patient who underwent liver transplantation 79 days later.
authors.affiliation: Center for Interventional Oncology, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, U.S.A. ; Lerner College of Medicine, Cleveland Clinic, Cleveland, OH, U.S.A.
authors.forename: C W
authors.initials: CW
authors.lastname: Hong
authors.forename: S K
authors.initials: SK
authors.lastname: Libutti
authors.forename: B J
authors.initials: BJ
authors.lastname: Wood
keywords: ablation; doxorubicin; hepatocellular carcinoma; liposomes; rfa