title: High rates of relationship dissolution among heterosexual HIV-serodiscordant couples in Kenya.
abstract: HIV-1 serodiscordant couples may experience increased risks of relationship dissolution; however, longitudinal stability of these relationships is poorly understood. We determined rates and correlates of separation among 469 serodiscordant couples in Nairobi and found that 113 (24 %) separated during 2 years of follow-up. Couples with a female HIV-1 infected partner (F+M-) and no income were more likely to separate than M+F- couples without income (HR = 5.0; 95 % CI 1.1-25.0), and F+M- and M+F- couples with income (HR = 2.4; 95 % CI 1.3-4.5 and HR = 2.3; 95 % CI 1.2-4.8, respectively). High separation rates may be important for couple support services and for conducting discordant couple studies.
authors.affiliation: Department of Epidemiology, University of Washington, 325 Ninth Avenue, Seattle, WA, 98104, USA, romelm@u.washington.edu.
authors.forename: Romel D
authors.initials: RD
authors.lastname: Mackelprang
authors.forename: Rose
authors.initials: R
authors.lastname: Bosire
authors.forename: Brandon L
authors.initials: BL
authors.lastname: Guthrie
authors.forename: Robert Y
authors.initials: RY
authors.lastname: Choi
authors.forename: Amy
authors.initials: A
authors.lastname: Liu
authors.forename: Anne
authors.initials: A
authors.lastname: Gatuguta
authors.forename: Anne F
authors.initials: AF
authors.lastname: Rositch
authors.forename: James N
authors.initials: JN
authors.lastname: Kiarie
authors.forename: Carey
authors.initials: C
authors.lastname: Farquhar
mesh_terms: D044966:Anti-Retroviral Agents / Q000008:administration & dosage; D005191:Family Characteristics; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000188:drug therapy / Q000517:prevention & control* / Q000635:transmission; D007722:Health Knowledge, Attitudes, Practice; D020010:Heterosexuality; D006801:Humans; D007398:Interpersonal Relations; D007630:Kenya; D008297:Male; D060728:Reproductive Health; D012307:Risk Factors; D012725:Sexual Behavior; D012747:Sexual Partners / Q000523:psychology*
chemical_list: D044966:Anti-Retroviral Agents