title: Identification and quantification of furanocoumarins in stem bark and wood of eight Algerian varieties of Ficus carica by RP-HPLC-DAD and RP-HPLC-DAD-MS.
abstract: Furanocoumarins are the major phytoalexins of Ficus carica and are effective natural drug candidates for treatment of several types of cancer and skin disease. The objectives of this study were to analyze and quantify linear furanocoumarins, mainly psoralen and bergapten, in wood and bark of stems from eight Algerian varieties of fig and to establish the differences in the content of these metabolites in the eight local samples. Psoralen and bergapten contents in the stem bark and wood (in microg/g DW) varied respectively from 146.6 to 1110.3 and from 395.7 to 1671.8 for psoralen, and from 114.3 to 524.0 and from 144.2 to 718.6 for bergapten. This study fills a gap in our knowledge of furanocoumarin distribution in different parts of the fig tree. Psoralen and bergapten concentrations were higher in the wood than in the stem bark. Most of the dark fruited fig trees produce these two coumarins more than the green ones.
authors.affiliation: Laboratoire de Chimie Appliquée, Université du 8 Mai 1945, Guelma 24000, Algérie.
authors.forename: Samia
authors.initials: S
authors.lastname: Rouaiguia-Bouakkaz
authors.forename: Habiba
authors.initials: H
authors.lastname: Amira-Guebailia
authors.forename: Céline
authors.initials: C
authors.lastname: Rivière
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Delaunay
authors.forename: Pierre
authors.initials: P
authors.lastname: Waffo-Téguo
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Mérillon
mesh_terms: D000462:Algeria; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D030681:Ficus / Q000737:chemistry*; D011564:Furocoumarins / Q000032:analysis*; D024301:Plant Bark / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry
chemical_list: D011564:Furocoumarins