title: Multicenter cross-sectional analysis of values of glycated haemoglobin (HbA1c) in Polish children and adolescents with long-term type 1 diabetes in Poland: PolPeDiab study group.
abstract: BACKGROUND
  Glycated haemoglobin is currently a golden standard of evaluation of metabolic control of diabetes. According to the Evidence based Medicine data, better metabolic control of diabetes decreases the prevalence of chronic complications.
  
  
  OBJECTIVE
  to analyse HbA1c in children with a longer duration of type 1 diabetes mellitus (t1DM).
  
  
  METHODS
  We analysed an epidemiological database (2006-2009) of 7783 HbA1c values of 996 children (465 girls) with t1DM treated at three academic centres (Gdańsk, Łódź, Katowice) in Poland. the mean age was 13.04±3.43 years and the mean duration of diabetes was 6.93±2.33 years.
  
  
  RESULTS
  the overall mean HbA1c was 7.6±1.5% (by age groups: 7.0±0.8%, 2-5 yrs; 7.1±1.0%, 6-10 yrs; 7.8±1.7%, 11-19 yrs) without gender-related differences. HbA1c increased significantly with increasing age and t1DM duration. HbA1c values differed significantly between the centres. A group of 455 (55.7%) children reached a stable course of diabetes with HbA1c <7.5%, and 110 (13.5%) had HbA1c levels >9%. The mean HbA1c ?6.5% was found in 150 children (18.4%).
  
  
  CONCLUSIONS
  In more than 50% of Polish children with longer t1DM duration, the international target of glycaemic control (HbA1c) is achieved; however, only 18% of them reached Polish national target. Age, t1DM duration and centre-specific factors influence the HbA1c values.
authors.affiliation: Department of paediatrics, Medical University of Silesia, Poland. pjarosz-chobot@sum.edu.pl
authors.forename: Przemysława
authors.initials: P
authors.lastname: Jarosz-Chobot
authors.forename: Joanna
authors.initials: J
authors.lastname: Polańska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Myśliwiec
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Szadkowska
authors.forename: Wojciech
authors.initials: W
authors.lastname: Fendler
authors.forename: Halla
authors.initials: H
authors.lastname: Kamińska
authors.forename: Miron
authors.initials: M
authors.lastname: Chumiecki
authors.forename: Beata
authors.initials: B
authors.lastname: Mianowska
authors.forename: Ilona
authors.initials: I
authors.lastname: Techmańska
authors.forename: Beata
authors.initials: B
authors.lastname: Sztangierska
authors.forename: Wojciech
authors.initials: W
authors.lastname: Młynarski
mesh_terms: D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000188:drug therapy / Q000453:epidemiology; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D011044:Poland / Q000453:epidemiology; D015995:Prevalence; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007328:Insulin