title: Anaemia in the older surgical patient: a review of prevalence, causes, implications and management.
abstract: This review provides the clinician with a summary of the causes, implications and potential treatments for the management of anaemia in the older surgical patient. The prevalence of anaemia increases with age and is frequently identified in older surgical patients. Anaemia is associated with increased postoperative morbidity and mortality. Allogenic blood transfusion is commonly used to treat anaemia but involves inherent risks and may worsen outcomes. Various strategies for the correction of pre- and postoperative anaemia have evolved. These include correction of nutritional deficiencies and the use of intravenous iron and erythropoesis stimulating therapy. Clear differences exist between the elective and emergency surgical populations and the translation of research findings into these individual clinical settings requires more work. This should lead to a standardized approach to the management of this frequently encountered clinical scenario.
authors.affiliation: Kings College London, London SW1 3QD, UK. judith.partridge@gstt.nhs.uk
authors.forename: Judith
authors.initials: J
authors.lastname: Partridge
authors.forename: Danielle
authors.initials: D
authors.lastname: Harari
authors.forename: Jessica
authors.initials: J
authors.lastname: Gossage
authors.forename: Jugdeep
authors.initials: J
authors.lastname: Dhesi
mesh_terms: D000375:Aging; D000740:Anemia / Q000209:etiology / Q000401:mortality / Q000628:therapy; D001803:Blood Transfusion; D002908:Chronic Disease; D003677:Deficiency Diseases / Q000150:complications*; D004920:Erythropoiesis; D006801:Humans; D007501:Iron / Q000627:therapeutic use; D000090463:Iron Deficiencies; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality / Q000628:therapy; D013514:Surgical Procedures, Operative; D065227:Transfusion Reaction
chemical_list: D007501:Iron