title: Treatment effects in prostate cancer following traditional and emerging therapies.
abstract: Treatment options for prostate cancer consist of radical prostatectomy, hormonal therapy and radiation therapy. Hormonal and radiation therapy have well-known, often profound, effects on the histological appearance of benign and malignant prostate tissue. Novel therapies including focal ablative treatments, chemotherapies and targeted molecular therapies are beginning to emerge and pathologists will play a central role in documenting the effects of these treatments at the tissue level. As such, knowledge of treatment-related changes and access to clinical information are essential to ensure accurate interpretation and reporting of post-treatment prostate specimens by pathologists.
authors.affiliation: Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Mazzucchelli
authors.forename: M
authors.initials: M
authors.lastname: Scarpelli
authors.forename: A
authors.initials: A
authors.lastname: Lopez-Beltran
authors.forename: L
authors.initials: L
authors.lastname: Cheng
authors.forename: R
authors.initials: R
authors.lastname: Di Primio
authors.forename: R
authors.initials: R
authors.lastname: Montironi
mesh_terms: D055011:Ablation Techniques; D000818:Animals; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D006801:Humans; D008297:Male; D058990:Molecular Targeted Therapy; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000628:therapy*; D035703:Therapies, Investigational; D016896:Treatment Outcome
chemical_list: D018931:Antineoplastic Agents, Hormonal