title: Dearomatization applications of I(III)reagents and some unusual reactivity amongst resorcinol derived cyclohexadienones.
abstract: The oxidative dearomatization of resorcinol derivatives, which are outfitted with a lactic acid derived chiral tether, and mitigated by hypervalent iodine derivatives of PhIO, affords stable chiral cyclohexadienones as useful building blocks for the construction of many highly functionalized chiral six and seven-membered ring systems. Herein, we report a multitude of remarkable and unexpected diastereoselective transformations stemming from these cyclohexadienone adducts.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106-9510, USA.
authors.forename: Todd A
authors.initials: TA
authors.lastname: Wenderski
authors.forename: Christophe
authors.initials: C
authors.lastname: Hoarau
authors.forename: Lupe
authors.initials: L
authors.lastname: Mejorado
authors.forename: Thomas R R
authors.initials: TR
authors.lastname: Pettus
keywords: Cyclohexadienone; Dearomatization; Hypervalent iodine; Lactone; Vinylogous ester