title: Rhodium-catalyzed highly regioselective hydroaminomethylation of styrenes with tetraphosphorus ligands.
abstract: The highly linear-selective hydroaminomethylation of styrenes is very challenging. Herein, an efficient, highly chemoselective, and linear-selective hydroaminomethylation (l/b up to >99:1) of styrenes using Rh(nbd)2SbF6 with a pyrrole-based 3,3',5,5'-substituted tetraphosphorus ligand is documented. This is in sharp contrast to other available processes leading to branched amines and provides a novel atom economic approach to 3-arylpropylamines.
authors.affiliation: College of Science, Northwest A&F University , Yangling, Shaanxi 712100, P. R. China, and, Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey , Piscataway, New Jersey 08854, United States.
authors.forename: Shengkun
authors.initials: S
authors.lastname: Li
authors.forename: Kexuan
authors.initials: K
authors.lastname: Huang
authors.forename: Jiwen
authors.initials: J
authors.lastname: Zhang
authors.forename: Wenjun
authors.initials: W
authors.lastname: Wu
authors.forename: Xumu
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000478:Alkylation; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D008024:Ligands; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D013343:Styrenes / Q000737:chemistry*
chemical_list: D000588:Amines; D008024:Ligands; D009943:Organophosphorus Compounds; D013343:Styrenes; D012238:Rhodium