title: Malignant odontogenic tumors: a multicentric Latin American study of 25 cases.
abstract: OBJECTIVE
  The aim of this study was to show the epidemiological features of 25 malignant odontogenic tumors (MOT) in Latin America.
  
  
  METHODS
  We retrieved 25 cases of MOT out of 2142 odontogenic tumors, from four oral diagnostic centers in Latin America, and described the main clinical and pathological characteristics.
  
  
  RESULTS
  A total of 19 cases were carcinomas, including eight ameloblastic carcinomas, five primary intra-osseous squamous cell carcinomas, three clear cell odontogenic carcinomas and three ghost cell odontogenic carcinomas. All six sarcomas corresponded to ameloblastic fibrosarcoma. Thirteen cases occurred in men and 12 in women, age ranged from 7 to 77 years old, with a mean of 41.4 years. The average age of patients with carcinomas and sarcomas were 48.53 and 19 years old, respectively.
  
  
  CONCLUSIONS
  As malignant odontogenic tumors are very rare, this series helps to better clarify their relative frequency, predominant subtypes, and clinical characteristics in Latin America.
authors.affiliation: Oral Pathology Section, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Brazil.
authors.forename: M
authors.initials: M
authors.lastname: Martínez Martínez
authors.forename: A
authors.initials: A
authors.lastname: Mosqueda-Taylor
authors.forename: R
authors.initials: R
authors.lastname: Carlos
authors.forename: W
authors.initials: W
authors.lastname: Delgado-Azañero
authors.forename: O P
authors.initials: OP
authors.lastname: de Almeida
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D007843:Latin America / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000453:epidemiology* / Q000473:pathology*; D009808:Odontogenic Tumors / Q000453:epidemiology* / Q000473:pathology*; D055815:Young Adult
keywords: carcinoma; epidemiology; odontogenic tumors; sarcoma