title: Effect of water-soluble fraction of cherry tomatoes on the adhesion of probiotics and Salmonella to intestinal epithelial cells.
abstract: BACKGROUND
  Tomato is one of the most consumed vegetables in the world and contains many valuable nutritional components. Here we investigate the prebiotic effects of cherry tomatoes for improving gut health.
  
  
  RESULTS
  Water-soluble dietary fiber was prepared from fresh and processed (heat treatment at 80 °C for 15 min) cherry tomato samples, each with and without Viscozyme L treatment. In the adhesion assays, all water-soluble dietary fiber samples improved adhesion of probiotics (Lactobacillus rhamnosus and Bifidobacterium bifidum) to intestinal epithelial cells (Caco-2 cells). Heat treatment in the preparation of juice from cherry tomatoes showed no significant effect on the adhesion of probiotics to Caco-2 cells. The oligofructose content of samples affected the intestinal adhesion of probiotic bacteria, with higher oligosaccharide concentrations associated with greater adhesion of probiotics and more inhibition of the adhesion of pathogens to Caco-2 cells.
  
  
  CONCLUSIONS
  The present results suggest that cherry tomato can act as a prebiotic, with oligofructose potentially being one of its major prebiotic components.
authors.affiliation: Department of Biofood Analysis, Specialized Korea Polytechnics, Nonsan-si, 320-905, Korea.
authors.forename: Jong Ho
authors.initials: JH
authors.lastname: Koh
authors.forename: Narae
authors.initials: N
authors.lastname: Kim
authors.forename: Dahyun
authors.initials: D
authors.lastname: Hwang
authors.forename: Young-Hee
authors.initials: YH
authors.lastname: Lim
mesh_terms: D001422:Bacterial Adhesion / Q000187:drug effects*; D018938:Caco-2 Cells; D003106:Colon / Q000187:drug effects / Q000382:microbiology; D004043:Dietary Fiber; D004847:Epithelial Cells / Q000187:drug effects / Q000378:metabolism; D005638:Fruit / Q000737:chemistry; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects* / Q000382:microbiology; D018551:Solanum lycopersicum / Q000737:chemistry*; D009844:Oligosaccharides / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology*; D056692:Prebiotics; D019936:Probiotics; D012475:Salmonella / Q000187:drug effects* / Q000472:pathogenicity
chemical_list: D004043:Dietary Fiber; D009844:Oligosaccharides; D010936:Plant Extracts; D056692:Prebiotics
keywords: adhesion assay; cherry tomato; oligosaccharide; prebiotic; probiotic