title: Case report of skull metastasis from hepatocellular carcinoma after a liver transplant.
abstract: A solitary skull metastasis from hepatocellular carcinoma is rare. A 38-year-old man with hepatocellular carcinoma presented to our institution with a palpable temporal scalp mass. We took a magnetic resonance image, and discovered an enhanced and osteolytic skull tumor. The tumor was removed by an occipital craniectomy, and the histologic diagnosis was a cranial metastasis owing to hepatocellular carcinoma. A skull metastasis owing to hepatocellular carcinoma should be considered in the differential diagnosis in patients with a subcutaneous scalp mass. Although a distant metastasis can affect the prognosis of the patient, early treatment may improve survival.
authors.affiliation: Transplant Research Center, Department of Pathology, Shiraz University of Medical Science, Shiraz, IR Iran.
authors.forename: Negar
authors.initials: N
authors.lastname: Azarpira
authors.forename: Amirreza
authors.initials: A
authors.lastname: Dehghanian
authors.forename: Arash
authors.initials: A
authors.lastname: Safarian
authors.forename: Koorosh
authors.initials: K
authors.lastname: Kazemi
mesh_terms: D000328:Adult; D001706:Biopsy; D006528:Carcinoma, Hepatocellular / Q000556:secondary* / Q000601:surgery*; D059186:Chemoradiotherapy, Adjuvant; D003399:Craniotomy; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology* / Q000601:surgery*; D016031:Liver Transplantation; D008279:Magnetic Resonance Imaging; D008297:Male; D012086:Reoperation; D012888:Skull Neoplasms / Q000556:secondary* / Q000601:surgery*; D016896:Treatment Outcome