title: Effects of 45S5 bioglass on surface properties of dental enamel subjected to 35% hydrogen peroxide.
abstract: Tooth bleaching agents may weaken the tooth structure. Therefore, it is important to minimize any risks of tooth hard tissue damage caused by bleaching agents. The aim of this study was to evaluate the effects of applying 45S5 bioglass (BG) before, after, and during 35% hydrogen peroxide (HP) bleaching on whitening efficacy, physicochemical properties and microstructures of bovine enamel. Seventy-two bovine enamel blocks were prepared and randomly divided into six groups: distilled deionized water (DDW), BG, HP, BG before HP, BG after HP and BG during HP. Colorimetric and microhardness tests were performed before and after the treatment procedure. Representative specimens from each group were selected for morphology investigation after the final tests. A significant color change was observed in group HP, BG before HP, BG after HP and BG during HP. The microhardness loss was in the following order: group HP>BG before HP, BG after HP>BG during HP>DDW, BG. The most obvious morphological alteration of was observed on enamel surfaces in group HP, and a slight morphological alteration was also detected in group BG before HP and BG after HP. Our findings suggest that the combination use of BG and HP could not impede the tooth whitening efficacy. Using BG during HP brought better protective effect than pre/post-bleaching use of BG, as it could more effectively reduce the mineral loss as well as retain the surface integrity of enamel. BG may serve as a promising biomimetic adjunct for bleaching therapy to prevent/restore the enamel damage induced by bleaching agents.
authors.affiliation: Department of Endodontics and Operative Dentistry, Sichuan University, Chengdu, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Deng
authors.forename: Hai-Lin
authors.initials: HL
authors.lastname: Wen
authors.forename: Xiao-Li
authors.initials: XL
authors.lastname: Dong
authors.forename: Feng
authors.initials: F
authors.lastname: Li
authors.forename: Xin
authors.initials: X
authors.lastname: Xu
authors.forename: Hong
authors.initials: H
authors.lastname: Li
authors.forename: Ji-Yao
authors.initials: JY
authors.lastname: Li
authors.forename: Xue-Dong
authors.initials: XD
authors.lastname: Zhou
mesh_terms: D000818:Animals; D040761:Biomimetic Materials / Q000032:analysis / Q000627:therapeutic use; D002417:Cattle; D002516:Ceramics / Q000032:analysis / Q000737:chemistry; D055598:Chemical Phenomena; D003116:Color; D003124:Colorimetry; D003743:Dental Enamel / Q000187:drug effects / Q000648:ultrastructure*; D004577:Electron Probe Microanalysis; D005898:Glass / Q000032:analysis / Q000737:chemistry; D006244:Hardness; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D008855:Microscopy, Electron, Scanning; D020011:Protective Agents / Q000032:analysis / Q000627:therapeutic use*; D011897:Random Allocation; D012995:Solubility; D017550:Spectroscopy, Fourier Transform Infrared; D013997:Time Factors; D014073:Tooth Bleaching / Q000379:methods; D058205:Tooth Bleaching Agents / Q000494:pharmacology*; D014867:Water / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D020011:Protective Agents; D058205:Tooth Bleaching Agents; C425330:bioactive glass 45S5; D014867:Water; D006861:Hydrogen Peroxide