title: DMEAS: DNA methylation entropy analysis software.
abstract: CONCLUSIONS
  DMEAS is the first user-friendly tool dedicated to analyze the distribution of DNA methylation patterns for the quantification of epigenetic heterogeneity. It supports the analysis of both locus-specific and genome-wide bisulfite sequencing data. DMEAS progressively scans the mapping results of bisulfite sequencing reads to extract DNA methylation patterns for contiguous CpG dinucleotides. It determines the DNA methylation level and calculates methylation entropy for genomic segments to enable the quantitative assessment of DNA methylation variations observed in cell populations.
  
  
  METHODS
  DMEAS program, user guide and all the testing data are freely available from http://sourceforge.net/projects/dmeas/files/
authors.affiliation: Center in Computation Biology, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
authors.forename: Jianlin
authors.initials: J
authors.lastname: He
authors.forename: Xinxi
authors.initials: X
authors.lastname: Sun
authors.forename: Xiaojian
authors.initials: X
authors.lastname: Shao
authors.forename: Liji
authors.initials: L
authors.lastname: Liang
authors.forename: Hehuang
authors.initials: H
authors.lastname: Xie
mesh_terms: D019175:DNA Methylation; D019277:Entropy; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D013447:Sulfites
chemical_list: D013447:Sulfites; C042345:hydrogen sulfite