title: Hemodynamic optimization in high-risk mitral valve repairs as a key component in surgical readiness.
abstract: Ensuring optimal readiness for surgery using a preoperative checklist has been shown to reduce perioperative morbidity and mortality in both elective and urgent surgeries. We recently introduced hemodynamic optimization as part of our preoperative preparedness strategy for cardiothoracic surgery. Here we describe the case of a patient with severe mitral regurgitation and suboptimal hemodynamics that was optimized preoperatively with nesiritide to reduce pulmonary hypertension. Postoperatively, the patient had an improvement of his heart failure from New York Heart Association functional class 3 to class 1. Without hemodynamic optimization the patient may have been considered too high-risk to undergo mitral valve repair. This case report illustrates the importance of a systemic approach with high-risk surgery, and the use of strategies that optimize key patient factors, including hemodynamics, prior to all elective and urgent procedures.
authors.affiliation: Department of Internal Medicine, Marshfield Clinic, 1000 N Oak Ave, Marshfield, WI 54449, USA. kanth.rajan@marshfieldclinic.org
authors.forename: Rajan
authors.initials: R
authors.lastname: Kanth
authors.forename: John H
authors.initials: JH
authors.lastname: Braxton
authors.forename: Charles S
authors.initials: CS
authors.lastname: McCauley
mesh_terms: D000368:Aged; D057189:Checklist; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D045283:Natriuretic Agents / Q000627:therapeutic use*; D020097:Natriuretic Peptide, Brain / Q000627:therapeutic use*; D011300:Preoperative Care / Q000379:methods*; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D045283:Natriuretic Agents; D020097:Natriuretic Peptide, Brain