title: Improvements in virological control among women conceiving on combination antiretroviral therapy in Western Europe.
abstract: Among 396 HIV-infected women conceiving on combination antiretroviral therapy and enrolled in the European Collaborative Study in 2000-2011, the proportion with virological failure (>200 copies/ml after ≥24 weeks of treatment) declined substantially from 34% in 2000-2001 to 3% in 2010-2011. In adjusted analyses, younger women and those with at least two children were at increased risk of virological failure, highlighting the importance of close monitoring and adherence support.
authors.affiliation: University College London, London, UK.
authors.forename: Heather
authors.initials: H
authors.lastname: Bailey
authors.forename: Claire L
authors.initials: CL
authors.lastname: Townsend
authors.forename: Mario
authors.initials: M
authors.lastname: Cortina-Borja
authors.forename: Claire
authors.initials: C
authors.lastname: Thorne
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D005060:Europe; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology*; D006801:Humans; D055118:Medication Adherence; D011247:Pregnancy; D017211:Treatment Failure; D019562:Viral Load
chemical_list: D044966:Anti-Retroviral Agents