title: Primary hyperparathyroidism as an extremely rare cause of secondary myelofibrosis in childhood.
abstract: Primary hyperparathyroidism (PHP) and myelofibrosis are rare entities in childhood. Myelofibrosis secondary to PHP is also extremely rare. We report a 15-year-old boy presented with generalized weakness, vomiting, and pallor. A parathyroid adenoma was detected on the left distal parathyroid gland. PHP was diagnosed together with hepatosplenomegaly and pancytopenia. Bone marrow biopsy revealed grade 3-4 reticulin fibrosis. As early as 2 months after the left distal parathyroidectomy, hematologic parameters improved without any other intervention. His liver and spleen also gradually decreased in size. We concluded that the pancytopenia was as a result of myelofibrosis from PHP.
authors.forename: Arzu
authors.initials: A
authors.lastname: Akyay
authors.forename: Gülçin
authors.initials: G
authors.lastname: Cihangiroglu
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Özkan
authors.forename: Ugur
authors.initials: U
authors.lastname: Deveci
authors.forename: Semiha
authors.initials: S
authors.lastname: Bahceci
authors.forename: Ziya
authors.initials: Z
authors.lastname: Çetinkaya
mesh_terms: D000293:Adolescent; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000150:complications*; D008297:Male; D055728:Primary Myelofibrosis / Q000209:etiology*