title: A novel hydrazino-substituted naphthalimide-based fluorogenic probe for tert-butoxy radicals.
abstract: A novel fluorogenic probe for tert-butoxy radicals based on the hydrazino-naphthalimide system is reported. Interestingly, different regioisomers exhibited significantly different optical properties toward ROS, which suggested 4-hydrazinyl naphthalimide as a potential new platform for the in vitro and in cellulo detection of alkoxyl radicals.
authors.affiliation: Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), School of Pharmacy, Shandong University, Jinan, Shandong 250012, China.
authors.forename: Zhao
authors.initials: Z
authors.lastname: Ma
authors.forename: Wei
authors.initials: W
authors.lastname: Sun
authors.forename: Laizhong
authors.initials: L
authors.lastname: Chen
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Zhenzhen
authors.initials: Z
authors.lastname: Liu
authors.forename: Haixiu
authors.initials: H
authors.lastname: Bai
authors.forename: Mengyuan
authors.initials: M
authors.lastname: Zhu
authors.forename: Lupei
authors.initials: L
authors.lastname: Du
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Shi
authors.forename: Minyong
authors.initials: M
authors.lastname: Li
mesh_terms: D000438:Alcohols / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D005609:Free Radicals / Q000032:analysis; D006834:Hydrazines / Q000737:chemistry*; D015394:Molecular Structure; D053644:Naphthalimides / Q000737:chemistry*
chemical_list: D000438:Alcohols; D005456:Fluorescent Dyes; D005609:Free Radicals; D006834:Hydrazines; D053644:Naphthalimides; C029424:hydrazine