title: Translationally related nearly identical molecules: 4-methoxyphenyl 4-O-[6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(fluoren-9-ylmethoxycarbonyl)-α-D-glucopyranosyl]-2-O-benzoyl-3-O-benzyl-6-O-chloroacetyl-β-D-glucopyranoside.
abstract: The title compound, C59H56ClN3O16, is an important dissacharide precursor to novel therapeutics for the treatment of Alzheimer's disease. It crystallizes with two independent enantiomerically identical molecules in almost exactly the same orientation in the cell, being one half cell-edge apart. Apart from the conformation of a single benzyl group, the molecules are superimposable. They are bound efficiently using complementary C-H···O(carbonyl) hydrogen bonds, principally along the `duplicating' axis. The absolute configurations were determined.
authors.affiliation: Callaghan Innovation Research Limited, PO Box 31-310, Lower Hutt, New Zealand. graeme.gainsford@callaghaninnovation.govt.nz
authors.forename: Graeme J
authors.initials: GJ
authors.lastname: Gainsford
authors.forename: Ralf
authors.initials: R
authors.lastname: Schwörer
authors.forename: Peter C
authors.initials: PC
authors.lastname: Tyler
mesh_terms: D001386:Azides / Q000138:chemical synthesis*; D018360:Crystallography, X-Ray; D004187:Disaccharides / Q000138:chemical synthesis*; D005449:Fluorenes / Q000138:chemical synthesis*; D008968:Molecular Conformation; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001386:Azides; D004187:Disaccharides; D005449:Fluorenes