title: Electrospun antibacterial chitosan-based fibers.
abstract: Chitosan is non-toxic, biocompatible, and biodegradable polysaccharide from renewable resources, known to have inherent antibacterial activity, which is mainly due to its polycationic nature. The combining of all assets of chitosan and its derivatives with the unique properties of electrospun nanofibrous materials is a powerful strategy to prepare new materials that can find variety of biomedical applications. In this article the most recent studies on different approaches for preparation of antibacterial fibrous materials from chitosan and its derivatives such as electrospinning, coating, and electrospinning-electrospraying, loading of drugs or bioactive nanoparticles are summarized.
authors.affiliation: Institute of Polymers, Laboratory of Bioactive Polymers, Bulgarian Academy of Sciences, Sofia, Bulgaria.
authors.forename: Milena
authors.initials: M
authors.lastname: Ignatova
authors.forename: Nevena
authors.initials: N
authors.lastname: Manolova
authors.forename: Iliya
authors.initials: I
authors.lastname: Rashkov
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000627:therapeutic use; D001672:Biocompatible Materials / Q000737:chemistry*; D048271:Chitosan / Q000737:chemistry* / Q000627:therapeutic use; D016503:Drug Delivery Systems; D006801:Humans; D008855:Microscopy, Electron, Scanning; D057139:Nanofibers / Q000737:chemistry / Q000648:ultrastructure; D053758:Nanoparticles / Q000737:chemistry / Q000648:ultrastructure
chemical_list: D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D048271:Chitosan
keywords: antibacterial activity; biomaterials; chitosan; electrospinning; hybrid nanofibers