title: Oxidative status in workers engaged in recycling of plastic: occupational hazard.
abstract: Recycling plastic industry is on rise. Plastic waste in environment is a pollutant so recycling of it can save environment and is economical too. However its recycling is associated with harmful effects on workers engaged in it. The present study was designed to elucidate the role of free radicals and cytochrome c in pathogenesis of polypropylene associated diseases. Thirty workers from plastic recycling factory occupationally exposed to polypropylene between the age of 18-40 years and working for atleast 8 hours a day for more than a year but less than 10 years were selected for the study. A trend in increase of FRAP and decrease of MDA was observed but they could not reach the level of significance. The level of serum cytochrome c, which is an indirect marker of oxidative stress, was also detectable in only two subjects. Since the number of subjects in the study was less, the result needs to be confirmed on larger number. More over cause of pulmonary dysfunction and carcinomas in these workers needs to be investigated.
authors.affiliation: Department of Physiology, University College of Medical Sciences (University of Delhi), Delhi, India. pc_mamc@yahoo.co.in
authors.forename: Prakash Chandra
authors.initials: PC
authors.lastname: Sati
authors.forename: Ravi
authors.initials: R
authors.lastname: Kaushik
authors.forename: Vinod
authors.initials: V
authors.lastname: Kumar
authors.forename: Farah
authors.initials: F
authors.lastname: Khaliq
authors.forename: Neelam
authors.initials: N
authors.lastname: Vaney
mesh_terms: D000328:Adult; D002617:Chemical Industry; D045304:Cytochromes c / Q000378:metabolism; D006801:Humans; D015227:Lipid Peroxidation; D009784:Occupational Diseases / Q000097:blood / Q000139:chemically induced* / Q000378:metabolism*; D016273:Occupational Exposure / Q000009:adverse effects*; D010084:Oxidation-Reduction; D011126:Polypropylenes / Q000506:poisoning*; D059027:Recycling
chemical_list: D011126:Polypropylenes; D045304:Cytochromes c