title: Presence of angina pectoris is related to extensive coronary artery disease in diabetic patients.
abstract: BACKGROUND
  Due to sensorial autonomic neuropathy, the type and severity of angina pectoris in patients with diabetes mellitus (DM) may be rather different from the type and severity of angina pectoris in patients without DM.
  
  
  OBJECTIVE
  The aim of the study was to understand if angina pectoris is related to extensive coronary artery disease (CAD) in patients with DM.
  
  
  METHODS
  The study included 530 patients with DM who underwent coronary angiography at our center in 2009 and 2010. Patients were divided into 4 groups according to type of chest pain: group 1, noncardiac chest pain or no pain; group 2, angina equivalent; group 3, atypical angina; and group 4, typical angina. All angiograms were re-evaluated and Gensini scores were calculated. Three-vessel disease was diagnosed in the presence of stenosis >50% in all 3 coronary artery systems.
  
  
  RESULTS
  There were no statistically significant differences between the groups with regard to age, sex, systolic or diastolic blood pressures, body mass index, creatinine clearance, or lipid profile. Fasting blood glucose was significantly higher in group 4 than in group 2. Gensini scores were not statistically different between groups 1 and 2 or between groups 3 and 4; however, the scores for groups 3 and 4 were higher than the score for either group 1 or group 2. Prevalence of 3-vessel disease was significantly higher in groups 3 and 4 compared with the other groups.
  
  
  CONCLUSIONS
  The presence of angina pectoris was related to extensive CAD in patients with DM. The extent of CAD was not correlated with the type of angina (typical or atypical).
authors.affiliation: Faculty of Medicine, Department of Cardiology, Gaziosmanpasa University, Tokat, Turkey.
authors.forename: Atac
authors.initials: A
authors.lastname: Celik
authors.forename: Metin
authors.initials: M
authors.lastname: Karayakali
authors.forename: Unal
authors.initials: U
authors.lastname: Erkorkmaz
authors.forename: Fatih
authors.initials: F
authors.lastname: Altunkas
authors.forename: Kayihan
authors.initials: K
authors.lastname: Karaman
authors.forename: Fatih
authors.initials: F
authors.lastname: Koc
authors.forename: Koksal
authors.initials: K
authors.lastname: Ceyhan
authors.forename: Hasan
authors.initials: H
authors.lastname: Kadi
authors.forename: Alaettin
authors.initials: A
authors.lastname: Avsar
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000453:epidemiology*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000453:epidemiology*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000453:epidemiology*; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012720:Severity of Illness Index; D014421:Turkey / Q000453:epidemiology