title: Peripapillary choroidal thickness in healthy Chinese subjects.
abstract: BACKGROUND
  To evaluate the peripapillary choroidal thickness of a healthy Chinese population, and to determine its influencing factors.
  
  
  METHODS
  A total of 76 healthy volunteers (76 eyes) without ophthalmic or systemic symptoms were enrolled. Choroidal scans (360-degree 3.4 mm diameter peripapillary circle scans) were obtained for all eyes using enhanced depth imaging spectral-domain optical coherence tomography. Choroid thickness was measured at the temporal, superotemporal, superior, superonasal, nasal, inferonasal, inferior, and inferotemporal segments.
  
  
  RESULTS
  The average peripapillary choroidal thicknesses were 165.03 ± 40.37 μm. Inferonasal, inferior, and inferotemporal thicknesses were significantly thinner than temporal, superotemporal, superior, superonasal, nasal thicknesses (p < 0.05). No statistically significant difference was found among inferonasal, inferior, and inferotemporal thicknesses. The average peripapillary choroidal thickness decreased linearly with age (β = -1.33, 95% CI -1.98, -0.68, P < 0.001). No correlation was noted between average choroidal thickness and other factors (gender, refractive error, axial length, average retinal nerve fiber layer thickness, intraocular pressure, diastolic blood pressure, systolic blood pressure, mean blood pressure, diastolic ocular perfusion pressure, systolic ocular perfusion pressure, and mean ocular perfusion pressure).
  
  
  CONCLUSIONS
  The inferonasal, inferior, inferotemporal peripapillary choroidal thicknesses were significantly thinner than temporal, superotemporal, superior, superonasal, and nasal thicknesses. A thinner peripapillary choroid is associated with increasing age.
authors.affiliation: Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-Sen University, Guangzhou, People's Republic of China.
authors.forename: Wenbin
authors.initials: W
authors.lastname: Huang
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Minwen
authors.initials: M
authors.lastname: Zhou
authors.forename: Shida
authors.initials: S
authors.lastname: Chen
authors.forename: Xinbo
authors.initials: X
authors.lastname: Gao
authors.forename: Qian
authors.initials: Q
authors.lastname: Fan
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Ding
authors.forename: Xiulan
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D044466:Asian People; D058452:Axial Length, Eye; D001794:Blood Pressure / Q000502:physiology; D002681:China; D002829:Choroid / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D041623:Tomography, Optical Coherence / Q000379:methods; D055815:Young Adult