title: Organocatalytic functionalization of heteroaromatic N-oxides with C-nucleophiles using in situ generated onium amide bases.
abstract: Organocatalytic functionalization of heteroaromatic N-oxides was investigated using in situ generated onium amide bases, and C-nucleophiles were efficiently introduced by the sequential addition-elimination reaction under metal-free conditions, affording 2-substituted nitrogen heteroaromatics generally in good to high yields.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Sendai 980-8578, Japan. inamoto@m.tohoku.ac.jp
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Inamoto
authors.forename: Yuta
authors.initials: Y
authors.lastname: Araki
authors.forename: Shoko
authors.initials: S
authors.lastname: Kikkawa
authors.forename: Misato
authors.initials: M
authors.lastname: Yonemoto
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kondo
mesh_terms: D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D009589:Nitrogen Oxides / Q000737:chemistry*; D009861:Onium Compounds / Q000737:chemistry*
chemical_list: D000577:Amides; D006571:Heterocyclic Compounds; D009589:Nitrogen Oxides; D009861:Onium Compounds