title: Pyoderma gangrenosum arising in a breast reduction scar: seven years post-procedure.
abstract: Pyoderma gangrenosum (PG) is an unusual skin condition causing inflammation and sterile ulceration. It may occur in the context of a systemic disease or in otherwise healthy patients following trauma. Treatment is immunosuppression. Surgical debridement may worsen the disease. Post-surgical PG of the breast is rare and in previous reports has occurred within days or weeks of surgery. We report a highly unusual case of PG occurring at an incision site seven years after reduction mammoplasty.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, UK.
authors.forename: A
authors.initials: A
authors.lastname: Segaran
authors.forename: M
authors.initials: M
authors.lastname: Mohammad
authors.forename: J C
authors.initials: JC
authors.lastname: Sterling
authors.forename: C M
authors.initials: CM
authors.lastname: Malata
mesh_terms: D000328:Adult; D002921:Cicatrix / Q000382:microbiology* / Q000473:pathology*; D003879:Dermatologic Agents / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage; D016462:Mammaplasty / Q000009:adverse effects*; D011239:Prednisolone / Q000008:administration & dosage; D017511:Pyoderma Gangrenosum / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D013997:Time Factors
chemical_list: D003879:Dermatologic Agents; D005938:Glucocorticoids; D011239:Prednisolone; D015474:Isotretinoin
keywords: Breast reduction; Immunosuppression; Inflammatory skin conditions; Isotretinoin; Late post-operative complications; Minocycline; Pyoderma gangrenosum; Reduction mammoplasty; Scarring; Tacrolimus; Ulcer