title: Recommendations for accurate numerical blood flow simulations of stented intracranial aneurysms.
abstract: The number of scientific publications dealing with stented intracranial aneurysms is rapidly increasing. Powerful computational facilities are now available; an accurate computational modeling of hemodynamics in patient-specific configurations is, however, still being sought. Furthermore, there is still no general agreement on the quantities that should be computed and on the most adequate analysis for intervention support. In this article, the accurate representation of patient geometry is first discussed, involving successive improvements. Concerning the second step, the mesh required for the numerical simulation is especially challenging when deploying a stent with very fine wire structures. Third, the description of the fluid properties is a major challenge. Finally, a founded quantitative analysis of the simulation results is obviously needed to support interventional decisions. In the present work, an attempt has been made to review the most important steps for a high-quality computational fluid dynamics computation of virtually stented intracranial aneurysms. In consequence, this leads to concrete recommendations, whereby the obtained results are not discussed for their medical relevance but for the evaluation of their quality. This investigation might hopefully be helpful for further studies considering stent deployment in patient-specific geometries, in particular regarding the generation of the most appropriate computational model.
authors.affiliation: Department of Fluid Dynamics and Technical Flows, University of Magdeburg Otto von Guericke, Magdeburg, Germany. janiga@ovgu.de
authors.forename: Gábor
authors.initials: G
authors.lastname: Janiga
authors.forename: Philipp
authors.initials: P
authors.lastname: Berg
authors.forename: Oliver
authors.initials: O
authors.lastname: Beuing
authors.forename: Mathias
authors.initials: M
authors.lastname: Neugebauer
authors.forename: Rocco
authors.initials: R
authors.lastname: Gasteiger
authors.forename: Bernhard
authors.initials: B
authors.lastname: Preim
authors.forename: Georg
authors.initials: G
authors.lastname: Rose
authors.forename: Martin
authors.initials: M
authors.lastname: Skalej
authors.forename: Dominique
authors.initials: D
authors.lastname: Thévenin
mesh_terms: D001783:Blood Flow Velocity; D002536:Cerebral Arteries / Q000503:physiopathology* / Q000601:surgery*; D003198:Computer Simulation; D006801:Humans; D002532:Intracranial Aneurysm / Q000503:physiopathology* / Q000601:surgery*; D008955:Models, Cardiovascular; D008959:Models, Neurological; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D015607:Stents; D025321:Surgery, Computer-Assisted / Q000379:methods*