title: [Congenital cardiac anomalies (pentalogy of Fallot) in a two year old ram with brachygnathia inferior].
abstract: In a nearly two-year-old ram, descending from a breeding trial to investigate the effects of shortness of the lower jaw (brachygnathia inferior), a congenital cardiac anomaly was observed. At the age often months the affected animal, a cross breed of Cameroon Sheep and East Friesian Milk Sheep, showed exercise-induced respiratory distress for the first time. Auscultation revealed a loud systolic heart murmur (grade 5) on both sides of the thorax, most prominent over the left third intercostal space at shoulder height. Postmortem examination of the ram's heart showed a pentalogy of Fallot, consisting of a pulmonic stenosis, a ventricular septal defect, an overriding aorta, a right ventricular hypertrophy and a patent foramen ovale. A genetic defect has to be considered as a possible reason.
authors.affiliation: Institut für Tierzucht und Vererbungsforschung, Stiftung Tierärztliche Hochschule Hannover, ricarda.pielmeier@tiho-hannover.de
authors.forename: Ricarda
authors.initials: R
authors.lastname: Pielmeier
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Engelke
authors.forename: Marko
authors.initials: M
authors.lastname: Legler
authors.forename: Verena
authors.initials: V
authors.lastname: Haist
authors.forename: Charlotte
authors.initials: C
authors.lastname: Hopster-Iversen
authors.forename: Ottmar
authors.initials: O
authors.lastname: Distl
mesh_terms: D000818:Animals; D001011:Aorta / Q000002:abnormalities; D003433:Crosses, Genetic; D054092:Foramen Ovale, Patent / Q000662:veterinary; D006330:Heart Defects, Congenital / Q000150:complications / Q000235:genetics / Q000662:veterinary*; D006345:Heart Septal Defects, Ventricular / Q000662:veterinary; D017380:Hypertrophy, Right Ventricular / Q000662:veterinary; D008297:Male; D008334:Mandible / Q000002:abnormalities*; D010375:Pedigree; D011666:Pulmonary Valve Stenosis / Q000662:veterinary; D012756:Sheep / Q000002:abnormalities*