title: Predictors of anticoagulant treatment in patients with nonvalvular atrial fibrillation: results from atrial fibrillation in Turkey: epidemiologic registry.
abstract: The aim of the study was to assess the factors associated with the anticoagulation treatment in patients with atrial fibrillation (AF). A total of 2242 consecutive patients who had been admitted with AF on their electrocardiogram were included in the study. After excluding valvular AF, 1745 patients with nonvalvular AF were analyzed. Mean CHA2DS2-VASc score [cardiac failure, hypertension, age ≥ 75 (doubled), diabetes, stroke (doubled), vascular disease, age 65 -74 and sex category (female)], frequency of persistent/permanent AF, hypertension, diabetes mellitus (DM), stroke history, body mass index, and left atrial diameter were significantly higher in patients receiving anticoagulant therapy. Stroke history, persistent/permanent AF, hypertension, DM, age, heart failure, and left atrial diameter were independent predictors of warfarin prescription. Labile international normalized ratio was the only independent negative predictor of effective treatment with warfarin. In this study, we demonstrated that stroke history, persistent/permanent AF, hypertension, DM, and left atrial diameter were positive predictors, whereas advanced age and heart failure were negative predictors of oral anticoagulant use in patients with nonvalvular AF.
authors.affiliation: Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey dr_hasankaya@yahoo.com.
authors.forename: Hasan
authors.initials: H
authors.lastname: Kaya
authors.affiliation: Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey.
authors.forename: Faruk
authors.initials: F
authors.lastname: Ertaş
authors.affiliation: Department of Cardiology, Siyami Ersek Education and Research Hospital, Istanbul, Turkey.
authors.forename: Bayram
authors.initials: B
authors.lastname: Köroğlu
authors.affiliation: Department of Cardiology, Sakarya University Faculty of Medicine, Sakarya, Turkey.
authors.forename: Bülent
authors.initials: B
authors.lastname: Vatan
authors.affiliation: Department of Cardiology, Numune Education and Research Hospital, Adana, Turkey.
authors.forename: Çağlar Emre
authors.initials: ÇE
authors.lastname: Çağlıyan
authors.affiliation: Department of Cardiology, Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Selçuk
authors.initials: S
authors.lastname: Gedik
authors.affiliation: Department of Cardiology, Yildirim Beyazit University, Diskapi Education and Research Hospital, Ankara, Turkey.
authors.forename: Ekrem
authors.initials: E
authors.lastname: Yeter
authors.affiliation: Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey.
authors.forename: Mesut
authors.initials: M
authors.lastname: Aydin
authors.affiliation: Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey.
authors.forename: Mehmet Ata
authors.initials: MA
authors.lastname: Akil
authors.affiliation: Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey.
authors.forename: Mehmet Serdar
authors.initials: MS
authors.lastname: Soydinç
authors.affiliation: Department of Cardiology, Duzce University Faculty of Medicine, Duzce, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Ozhan
authors.affiliation: Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey.
authors.forename: Mehmet Sıddık
authors.initials: MS
authors.lastname: Ülgen
mesh_terms: D000284:Administration, Oral; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000008:administration & dosage* / Q000493:pharmacokinetics; D001281:Atrial Fibrillation / Q000097:blood / Q000188:drug therapy* / Q000453:epidemiology* / Q000503:physiopathology; D004562:Electrocardiography; D006333:Heart Failure / Q000097:blood / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology; D006801:Humans; D019934:International Normalized Ratio; D008297:Male; D008875:Middle Aged; D012042:Registries; D012307:Risk Factors; D012737:Sex Factors; D014421:Turkey / Q000453:epidemiology
chemical_list: D000925:Anticoagulants
keywords: anticoagulant treatment; atrial fibrillation; nonvalvular; predictor