title: A 17-year-old female with systemic lupus presents with complex movement disorder: possible relationship with antiribosomal p antibodies.
abstract: Complex movement disorder is a relatively rare presentation of neurolupus. Antiphospholipid antibodies are associated with movement disorders likely via aberrant neuronal stimulation. Antiribosomal P antibodies have been previously associated with neuropsychiatric disorders but their correlation with movement disorder was not previously established. Our case report involves a 17-year-old Caucasian female patient positive for only antiribosomal P antibody and lupus anticoagulant who presented with a sudden onset of complex movement disorder. After complete cessation of physical signs with olanzapine, anticardiolipin and anti- β 2 glycoprotein I antibodies became positive which indicates a likely discordance between movement disorder and antiphospholipid antibodies. This also indicates a potential causal role of antiribosomal P antibodies in inducing movement disorder.
authors.affiliation: Department of Neurology, Bezmialem Vakıf University, Adnan Menderes Bulvarı, Vatan Caddesi, 34093 Fatih İstanbul, İstanbul, Turkey.
authors.forename: Muhammed Emin
authors.initials: ME
authors.lastname: Ozcan
authors.forename: Meriç Adil
authors.initials: MA
authors.lastname: Altınöz
authors.forename: Hasan Hüseyin
authors.initials: HH
authors.lastname: Karadeli
authors.forename: Talip
authors.initials: T
authors.lastname: Asil
authors.forename: Abdulkadir
authors.initials: A
authors.lastname: Koçer