title: [Neurophysiological monitoring of the efficacy of the complex therapy of vascular and posttraumatic encephalopathy].
abstract: Authors have studied the efficacy of adaptol and neyromidin in the combined treatment of patients with chronic cerebral circulation insufficiency and consequences of closed head injury using neurophysiological monitoring which included dynamic evaluation of central conductivity, neuropsychological tests and analysis of blood BDNF levels. Severe autonomic disorders, anxiety and low level of learning observed in all patients are correlated with neurophysiological (increased central conductivity time) and neurotrophic (decreased blood BDNF levels) profiles. These indicators may change throughout the treatment. The combination of adaptol and neyromidin enhanced greatly the efficacy of combined treatment. The received data allow recommending neurophysiological monitoring for treatment optimization of numerous neurological diseases that demand neuroplasticity stimulation.
authors.affiliation: Kirov Academy of Military Medicine, St. Petersburg, Russia
authors.forename: S A
authors.initials: SA
authors.lastname: Zhivolupov
authors.forename: I N
authors.initials: IN
authors.lastname: Samartsev
authors.forename: A A
authors.initials: AA
authors.lastname: Marchenko
authors.forename: O V
authors.initials: OV
authors.lastname: Puljatkina
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000634:Aminoquinolines / Q000009:adverse effects / Q000627:therapeutic use; D001007:Anxiety / Q000188:drug therapy; D001736:Biureas / Q000009:adverse effects / Q000627:therapeutic use; D001930:Brain Injuries / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D002545:Brain Ischemia / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D058256:Brain Waves / Q000187:drug effects; D019208:Brain-Derived Neurotrophic Factor / Q000097:blood; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007858:Learning / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009473:Neuronal Plasticity / Q000187:drug effects; D009483:Neuropsychological Tests; D016896:Treatment Outcome
chemical_list: D000634:Aminoquinolines; D001736:Biureas; D019208:Brain-Derived Neurotrophic Factor; C015979:mebikar; C049860:amiridine