title: Expression of DPP6 in Meckel's cartilage and tooth germs during mouse facial development.
abstract: Dipeptidyl peptidase-like protein 6 (DPP6), a member of the dipeptidyl aminopeptidase family, plays distinct roles in brain development, but its expression in embryonic Meckel's cartilage and tooth germs development is unknown. We analyzed the expression pattern of DPP6 in Meckel's cartilage and tooth germs development using in situ hybridization. DPP6 was detected in different patterns in Meckel's cartilage and tooth germs during mouse facial development from 11.5 to 13.5 days post-coitus (dpc) embryos. The expression pattern of DPP6 suggests that it may be involved in mandible and tooth development.
authors.affiliation: Molecular Laboratory for Gene Therapy & Tooth Regeneration, Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology , Tian Tan Xi Li No.4, Beijing 100050.
authors.forename: J
authors.initials: J
authors.lastname: Du
authors.forename: Z
authors.initials: Z
authors.lastname: Fan
authors.forename: X
authors.initials: X
authors.lastname: Ma
authors.forename: Y
authors.initials: Y
authors.lastname: Wu
authors.forename: S
authors.initials: S
authors.lastname: Liu
authors.forename: Y
authors.initials: Y
authors.lastname: Gao
authors.forename: Y
authors.initials: Y
authors.lastname: Shen
authors.forename: M
authors.initials: M
authors.lastname: Fan
authors.forename: S
authors.initials: S
authors.lastname: Wang
mesh_terms: D000818:Animals; D002356:Cartilage / Q000196:embryology*; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental; D017403:In Situ Hybridization; D008334:Mandible / Q000196:embryology*; D051379:Mice; D009419:Nerve Tissue Proteins / Q000235:genetics*; D015221:Potassium Channels / Q000235:genetics*; D012313:RNA / Q000378:metabolism; D014083:Tooth Germ / Q000196:embryology*
chemical_list: D009419:Nerve Tissue Proteins; D015221:Potassium Channels; D012313:RNA; C503535:DPP6 protein, human; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases