title: First report of the multiresistance gene cfr in Streptococcus suis.
abstract: The multiresistance gene cfr was identified for the first time in streptococci, namely, in porcine Streptococcus suis isolate S10. The cfr gene was detected on the ~100-kb plasmid pStrcfr, where it was bracketed by two copies of the novel insertion sequence ISEnfa5, located in the same orientation. The detection of a cfr- and ISEnfa5-containing amplicon by inverse PCR suggests that ISEnfa5 may play a role in the dissemination of cfr.
authors.affiliation: Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Wang
authors.forename: Dexi
authors.initials: D
authors.lastname: Li
authors.forename: Li
authors.initials: L
authors.lastname: Song
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Tao
authors.initials: T
authors.lastname: He
authors.forename: Hebing
authors.initials: H
authors.lastname: Liu
authors.forename: Congming
authors.initials: C
authors.lastname: Wu
authors.forename: Stefan
authors.initials: S
authors.lastname: Schwarz
authors.forename: Jianzhong
authors.initials: J
authors.lastname: Shen
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D001483:Base Sequence; D004251:DNA Transposable Elements; D005798:Genes, Bacterial; D019450:Genes, MDR; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics / Q000378:metabolism; D017011:Streptococcus suis / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D013552:Swine; D013839:Thiamphenicol / Q000031:analogs & derivatives / Q000494:pharmacology; D014169:Transformation, Bacterial
chemical_list: D001426:Bacterial Proteins; D004251:DNA Transposable Elements; C035534:florfenicol; D013839:Thiamphenicol