title: Survival of acute hypernatremia due to massive soy sauce ingestion.
abstract: BACKGROUND
  Intentional massive sodium chloride ingestions are rare occurrences and are often fatal.
  
  
  OBJECTIVE
  There are a variety of treatment recommendations for hypernatremia, ranging from dialysis to varying rates of correction. We report a case of acute severe hypernatremia corrected with rapid free-water infusions that, to our knowledge, has not been previously reported.
  
  
  METHODS
  A 19-year-old man presented to the Emergency Department in a comatose state with seizure-like activity 2 hours after ingesting a quart of soy sauce. He was administered 6 L of free water over 30 min and survived neurologically intact without clinical sequelae. Corrected for hyperglycemia, the patient's peak serum sodium was 196 mmol/L, which, to our knowledge, is the highest documented level in an adult patient to survive an acute sodium ingestion without neurologic deficits.
  
  
  CONCLUSIONS
  Emergency physicians should consider rapidly lowering serum sodium with hypotonic intravenous fluids as a potential management strategy for acute severe hypernatremia secondary to massive salt ingestion.
authors.affiliation: Department of Emergency Medicine, University of Virginia Medical Center, Charlottesville, Virginia, USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Carlberg
authors.forename: Heather A
authors.initials: HA
authors.lastname: Borek
authors.forename: Scott A
authors.initials: SA
authors.lastname: Syverud
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Holstege
mesh_terms: D000208:Acute Disease; D006801:Humans; D006955:Hypernatremia / Q000139:chemically induced*; D008297:Male; D012982:Sodium, Dietary / Q000506:poisoning*; D045730:Soy Foods / Q000506:poisoning*; D055815:Young Adult
chemical_list: D012982:Sodium, Dietary
keywords: acute hypernatremia; hypotonic fluids; resuscitation; sodium chloride