title: Cutaneous leukocytoclastic vasculitis in the presence of methimazole therapy.
abstract: Treatment with antithyroid drugs may be accompanied by side effects. We present a patient diagnosed with Grave's Disease who developed extensive vasculitis in the lower limbs during methimazole use. After suspension of the methimazole and the introduction of prednisone in immunesupressor doses the cutaneous lesions started to involute.
authors.affiliation: Dermatology Department, Antônio Pedro University Hospital, Universidade Federal Fluminense, Niterói, (RJ), Brazil. carla_ribb@yahoo.com.br
authors.forename: Carla de Oliveira
authors.initials: Cde O
authors.lastname: Ribeiro
authors.forename: Paula Ferrazzi
authors.initials: PF
authors.lastname: Magrin
authors.forename: Enoí Aparecida Guedes
authors.initials: EA
authors.lastname: Vilar
authors.forename: Sandra Maria Barbosa
authors.initials: SM
authors.lastname: Durães
authors.forename: Rogério Ribeiro
authors.initials: RR
authors.lastname: Estrella
mesh_terms: D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D013956:Antithyroid Agents / Q000009:adverse effects*; D001706:Biopsy; D006111:Graves Disease / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008713:Methimazole / Q000009:adverse effects*; D011241:Prednisone / Q000627:therapeutic use; D016896:Treatment Outcome; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000139:chemically induced* / Q000473:pathology
chemical_list: D018931:Antineoplastic Agents, Hormonal; D013956:Antithyroid Agents; D008713:Methimazole; D011241:Prednisone