title: Psychrotrophic yeast Yarrowia lipolytica NCYC 789 mediates the synthesis of antimicrobial silver nanoparticles via cell-associated melanin.
abstract: A psychrotrophic marine strain of the ascomycetous yeast Yarrowia lipolytica (NCYC 789) synthesized silver nanoparticles (AgNPs) in a cell-associated manner. These nanostructures were characterized by UV-Visible spectroscopy and scanning electron microscope-energy dispersive spectrometer (SEM-EDS) analysis. The brown pigment (melanin) involved in metal-interactions was obtained from the cells. This extracted pigment also mediated the synthesis of silver nanoparticles that were characterized by a variety of analytical techniques. The melanin-derived nanoparticles displayed antibiofilm activity. This paper thus reports the synthesis of AgNPs by the biotechnologically important yeast Y. lipolytica; proposes a possible mechanism involved in the synthetic process and describes the use of the bio-inspired nanoparticles as antibiofilm agents.
authors.affiliation: Institute of Bioinformatics and Biotechnology, University of Pune, Pune, 411007, India. smita@unipune.ac.in.
authors.forename: Mugdha
authors.initials: M
authors.lastname: Apte
authors.forename: Devashree
authors.initials: D
authors.lastname: Sambre
authors.forename: Shital
authors.initials: S
authors.lastname: Gaikawad
authors.forename: Swanand
authors.initials: S
authors.lastname: Joshi
authors.forename: Ashok
authors.initials: A
authors.lastname: Bankar
authors.forename: Ameeta Ravi
authors.initials: AR
authors.lastname: Kumar
authors.forename: Smita
authors.initials: S
authors.lastname: Zinjarde