title: MicroRNA-132 may play a role in coexistence of depression and cardiovascular disease: a hypothesis.
abstract: Different individuals have different degrees of neuroplasticity due to their different experiences. Neuroplasticity may play a role in individual differences among neuropsychiatric disease treatment efficacy. Since the nervous system monitors and coordinates internal organ function, neuroplasticity may be associated with other diseases. Cardiovascular disease (CVD) is associated with depression, which is a disorder of disrupted neuroplasticity. MicroRNA-132 (miR-132) has a roles in neuroplasticity and cardiovascular function. Thus, we hypothesize that miR-132 may play a role in coexistence of depression and CVD.
authors.affiliation: Guangdong Province Pharmaceutical Association, Guangzhou, China. snownotrace@gmail.com
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Zheng
authors.forename: Yingtong
authors.initials: Y
authors.lastname: Zeng
authors.forename: Hongbing
authors.initials: H
authors.lastname: Huang
authors.forename: Feng
authors.initials: F
authors.lastname: Xu
mesh_terms: D002318:Cardiovascular Diseases / Q000150:complications* / Q000235:genetics*; D002319:Cardiovascular System / Q000378:metabolism / Q000473:pathology; D003863:Depression / Q000150:complications* / Q000235:genetics* / Q000503:physiopathology; D006801:Humans; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism*; D008954:Models, Biological; D009473:Neuronal Plasticity / Q000235:genetics
chemical_list: C547077:MIRN132 microRNA, human; D035683:MicroRNAs