title: Hydrophosphinylation of unactivated terminal alkenes catalyzed by nickel chloride.
abstract: The room-temperature hydrophosphinylation of unactivated monosubstituted alkenes using phosphinates (ROP(O)H2) and catalytic NiCl2 in the presence of dppe is described. The method is competitive with prior palladium-catalyzed reactions and uses a much cheaper catalyst and simple conditions. The scope of the reaction is quite broad in terms of unactivated terminal olefins, proceeds at room temperature, often avoids chromatographic purification, and allows one-pot conversion to various organophosphorus compounds.
authors.affiliation: Department of Chemistry, Box 298860, Texas Christian University, Fort Worth, Texas 76129, USA.
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Ortial
authors.forename: Henry C
authors.initials: HC
authors.lastname: Fisher
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Montchamp
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010721:Phosphinic Acids / Q000737:chemistry
chemical_list: D000475:Alkenes; D009943:Organophosphorus Compounds; D010721:Phosphinic Acids; C022838:nickel chloride; D009532:Nickel