title: A case of late herpes simplex encephalitis relapse.
abstract: Late relapse of herpes simplex encephalitis, defined as recurrence more than 3 months after the first initial encephalitic episode, is a rare condition. We describe the case of an adult patient who presented a relapse of herpes simplex encephalitis 8 years after the first episode occurred at the age of 57 years and review the literature of this topic.
authors.affiliation: Department of Neurology, Alessandro Manzoni Hospital, Via Dell'Eremo 9/11, 23900 Lecco, Italy. rig74@libero.it
authors.forename: Andrea
authors.initials: A
authors.lastname: Rigamonti
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lauria
authors.forename: Vittorio
authors.initials: V
authors.lastname: Mantero
authors.forename: Andrea
authors.initials: A
authors.lastname: Salmaggi
mesh_terms: D000328:Adult; D020803:Encephalitis, Herpes Simplex / Q000175:diagnosis* / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D013997:Time Factors
keywords: CPAP-NIV; CSF; CT; EEG; Encephalitis; HIV; HSE; HSV; Herpes simplex; ICU; MRI; PCR; PLEDs; Relapse; cerebrospinal fluid; computed tomography; continuous positive airways pressure non-invasive ventilation; electroencephalography; herpes simplex encephalitis; herpes simplex virus; human immunodeficiency virus; intensive care unit; magnetic resonance imaging; periodic lateralized epileptic discharges; positive polymerase chain reaction