title: Necrotizing fasciitis in a pediatric orthopedic population.
abstract: Few studies have analyzed necrotizing fasciitis in children, and all have relied on cases of necrotizing fasciitis in the abdomen, head, and neck region. The authors sought to correlate the preoperative values of several laboratory tests previously validated in the adult literature, such as the Laboratory Risk Indicator for Necrotizing Fasciitis, with surgically confirmed necrotizing fasciitis in children to provide clinical guidance for the preoperative laboratory workup of necrotizing fasciitis. A retrospective chart review was performed on consecutive patients younger than 18 years with a diagnosis of necrotizing fasciitis. A total of 13 patients with an average age of 7.9 years (range, 9 months-16 years) were included. Ten (76.9%) infections were found in the lower extremity and 3 (23.1%) in the upper extremity. Seven (53.8%) patients had ecchymosis on examination. All patients presented with an elevated white blood cell count. No amputations were performed, and no mortality occurred. All patients underwent surgery within 24 hours of presentation. Elevated temperature, white blood count, erythrocyte sedimentation rate, and C-reactive protein values are typically seen in pediatric patients with necrotizing fasciitis; however, no correlation existed between other the preoperative laboratory values with the previously described scoring systems, such as the Laboratory Risk Indicator for Necrotizing Fasciitis. Aggressive monitoring of signs and symptoms is suggested, even if a patient does not meet all conventional diagnostic criteria. The authors recommend prompt surgical debridement and early administration of antibiotics, which should include clindamycin.
authors.affiliation: Mount Carmel Medical Center, Nationwide Children’s Hospital, Columbus, OH 43205-2696, USA.
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Tancevski
authors.forename: Kenneth
authors.initials: K
authors.lastname: Bono
authors.forename: Leisel
authors.initials: L
authors.lastname: Willis
authors.forename: Kevin
authors.initials: K
authors.lastname: Klingele
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D019115:Fasciitis, Necrotizing / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D035002:Lower Extremity / Q000293:injuries; D008297:Male; D009820:Ohio / Q000453:epidemiology; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery