title: Bilateral endogenous Serratia marcescens endophthalmitis secondary to endocarditis following cardiac surgery.
abstract: BACKGROUND
  Endogenous endophthalmitis is a sight-threatening condition caused by microorganisms crossing the blood-ocular barrier and inducing profound intraocular inflammation.
  
  
  METHODS
  A 65-year-old female experienced bilateral loss of vision after developing infective endocarditis as a complication of combined Bentall procedure and coronary artery bypass grafting. She was diagnosed with bilateral endogenous endophthalmitis secondary to Serratia marcescens. Despite aggressive treatment with intravitreal injections of antibiotics and steroids, intensive topical and systemic antibiotic therapy, there was permanent loss of sight in both eyes.
  
  
  CONCLUSIONS
  The case highlights the importance of early recognition of the symptoms and signs of endogenous endophthalmitis in any patient with systemic infection by all clinicians and the necessity of prompt ophthalmological referral if a useful level of vision is to be preserved.
authors.affiliation: Tennent Institute of Ophthalmology, Gartnavel General Hospital, UK. douglasamlyall@gmail.com
authors.forename: D A M
authors.initials: DA
authors.lastname: Lyall
authors.forename: M E
authors.initials: ME
authors.lastname: Gregory
authors.forename: J
authors.initials: J
authors.lastname: McDonnell
authors.forename: F
authors.initials: F
authors.lastname: De Villiers
authors.forename: D
authors.initials: D
authors.lastname: Tejwani
mesh_terms: D000368:Aged; D001011:Aorta / Q000601:surgery; D001021:Aortic Valve / Q000601:surgery; D001026:Coronary Artery Bypass; D017548:Echocardiography, Transesophageal; D004696:Endocarditis / Q000150:complications*; D009877:Endophthalmitis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D011183:Postoperative Complications; D016868:Serratia Infections / Q000150:complications*; D012706:Serratia marcescens
keywords: Endogenous endophthalmitis; Serratia marcescens; blood–ocular barrier; endocarditis; intraocular inflammation