title: Prognostic Value of the Neutrophil-Lymphocyte Ratio in Patients With ST-Elevated Acute Myocardial Infarction.
abstract: The predictive value of leukocyte counts has been reported in patients with acute myocardial infarction (AMI). We aimed to evaluate the predictive value of the total leukocyte count and neutrophil-lymphocyte (N/L) ratio for mortality due to AMI. A total of 522 patients with acute ST-elevated MI were included in the study. The study population was divided into tertiles based on admission N/L ratio values. High (n = 174) and low N/L (n = 348) ratio groups were defined as patients having values in the third tertile (>5.77) and lower 2 tertiles (≤ 5.77), respectively. The high N/L ratio group had a significantly higher incidence of in-hospital cardiovascular mortality (13.8% vs 4.6%, P < .001). An N/L ratio >5.77 was found to be an independent predictor of in-hospital cardiovascular mortality (hazard ratio: 3.78, 95% confidence interval: 1.71-8.30, P = .001). A high N/L ratio is a strong and independent predictor of in-hospital cardiovascular mortality of AMI with ST elevation.
authors.affiliation: Department of Cardiology, Canakkale Onsekiz Mart University, Canakkale, Turkey eordulu@hotmail.com.
authors.forename: Emine
authors.initials: E
authors.lastname: Gazi
authors.affiliation: Department of Emergency Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Basak
authors.initials: B
authors.lastname: Bayram
authors.affiliation: Department of Cardiology, Canakkale State Hospital, Canakkale, Turkey.
authors.forename: Sabri
authors.initials: S
authors.lastname: Gazi
authors.affiliation: Department of Cardiology, Canakkale Onsekiz Mart University, Canakkale, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Temiz
authors.affiliation: Department of Cardiology, Canakkale Onsekiz Mart University, Canakkale, Turkey.
authors.forename: Bahadir
authors.initials: B
authors.lastname: Kirilmaz
authors.affiliation: Department of Cardiology, Canakkale Onsekiz Mart University, Canakkale, Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Altun
authors.affiliation: Department of Cardiology, Canakkale Onsekiz Mart University, Canakkale, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Barutcu
mesh_terms: D000368:Aged; D018572:Disease-Free Survival; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D018655:Lymphocyte Count; D008214:Lymphocytes; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000401:mortality*; D009504:Neutrophils; D011237:Predictive Value of Tests; D015996:Survival Rate
keywords: acute coronary syndrome; blood cell count; leukocyte count; myocardial infarction; neutrophil–lymphocyte ratio; prognosis