title: [Pathology diagnosis of idiopathic inflammatory myopathies].
abstract: The idiopathic inflammatory myopathies represent a group ofimmunologically mediated diseases characterized by inflammation of skeletal muscle potentially leading to irreversible damage. On the basis of clinical, histological and immunological features dermatomyositis, polymyositis and sporadic inclusion-body myositis are recognized as separate entities. A definitive diagnosis of idiopathic inflammatory myopathies requires detailed histological, histochemical, immunohistochemical and electron-microscopic analysis of adequate muscle biopsy sample. However, in spite of thorough morphological analysis distinction of these disorders is not always straightforward and a close clinicopathological correlation is often essential to reach a correct diagnosis. Detailed morphological features ofidiopathic inflammatory myopathies and their relationship to pathogenesis is outlined.
authors.affiliation: Klinicki zavod za patologiju Ljudevit Jurak, Klinicki bolnicki centar, Sestre milosrdnice, Vinogradska 29, 10000 Zagreb.
authors.forename: Leo
authors.initials: L
authors.lastname: Pazanin
mesh_terms: D001706:Biopsy; D003581:Cytodiagnosis; D003937:Diagnosis, Differential; D009220:Myositis / Q000175:diagnosis* / Q000473:pathology