title: Cytomegalovirus pneumonia in hematopoietic stem cell recipients.
abstract: Cytomegalovirus (CMV) is a frequently encountered infection following hematopoietic cell transplantation, and tissue invasive pneumonia is a dreaded complication of the virus in this population. In this review of CMV pneumonia, we address epidemiology, pathogenesis, diagnostics, current therapy, and strategies to prevent the development of CMV. We also review emerging treatment and prevention options for this challenging disease.
authors.affiliation: Department of Infectious Diseases, AO Ospedale Niguarda Cà Granda, Milan, Italy.
authors.forename: Giovanna
authors.initials: G
authors.lastname: Travi
authors.affiliation: Vaccine and Infectious Diseases and Clinical Research Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA, USA Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA spergam@fhcrc.org.
authors.forename: Steven A
authors.initials: SA
authors.lastname: Pergam
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D011024:Pneumonia, Viral / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors
chemical_list: D000998:Antiviral Agents
keywords: CMV pneumonia; antiviral; cytomegalovirus; hematopoietic cell transplant; prevention