title: Antioxidant and antimicrobial activities of Lycium shawii fruits extract.
abstract: Crude extracts from the fruit of Lycium shawii, a plant collected from the south of Tunisia, were screened for their in vitro antioxidant, antimicrobial and antifungal activities. The dried fruits were extracted with EtOH and an aqueous suspension of the obtained EtOH extract was partitioned successively with CHCl3, CH2Cl2, EtOAc and n-BuOH, leaving residual water extract. Total phenolic content of extracts from these fruits were also determined. β-Carotene bleaching assay and Folin-Ciocalteu reagent were used to determine total antioxidant activity and total phenols of fruit extracts. Total phenolic and flavonoid contents varied from 100 to 377 mg GAE/g DW and 3.3-110.6 mg quercetin/gDW, respectively. Several extracts showed high antioxidant capacity and an antimicrobial activity against different strains. This is, to our knowledge, the first report on the detail chemical composition, antioxidant and antimicrobial activities of L. shawii extracts. The results provided evidence that the studied fruit might indeed be potential sources of natural antioxidant and antimicrobial agents.
authors.affiliation: Biochemistry Laboratory, Department of Life Science, Faculty of Science, University of Sfax, PB 802, 3018 Sfax, Tunisia. imenbiologie@yahoo.fr
authors.forename: Imen
authors.initials: I
authors.lastname: Dahech
authors.forename: Wafa
authors.initials: W
authors.lastname: Farah
authors.forename: Mohamed
authors.initials: M
authors.lastname: Trigui
authors.forename: Anis
authors.initials: A
authors.lastname: Ben Hssouna
authors.forename: Hafedh
authors.initials: H
authors.lastname: Belghith
authors.forename: Karima Srih
authors.initials: KS
authors.lastname: Belghith
authors.forename: Ferjani
authors.initials: F
authors.lastname: Ben Abdallah
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology*; D005638:Fruit / Q000737:chemistry*; D032305:Lycium / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000975:Antioxidants; D010936:Plant Extracts
keywords: Antimicrobial activity; Antioxidant activity; Lycium shawii; Phenolic compounds