title: Rim15p-mediated regulation of sucrose utilization during molasses fermentation using Saccharomyces cerevisiae strain PE-2.
abstract: Inherited loss-of-function mutations in the Rim15p-mediated stress-response pathway contribute to the high fermentation rate of sake yeast strains. In the present study, we found that disruption of the RIM15 gene in ethanol-producing Saccharomyces cerevisiae strain PE-2 accelerated molasses fermentation through enhanced sucrose utilization following glucose starvation.
authors.affiliation: National Research Institute of Brewing, 3-7-1 Kagamiyama, Higashihiroshima, Hiroshima 739-0046, Japan.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Inai
authors.forename: Daisuke
authors.initials: D
authors.lastname: Watanabe
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhou
authors.forename: Rie
authors.initials: R
authors.lastname: Fukada
authors.forename: Takeshi
authors.initials: T
authors.lastname: Akao
authors.forename: Jun
authors.initials: J
authors.lastname: Shima
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takagi
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Shimoi
mesh_terms: D000434:Alcoholic Beverages / Q000382:microbiology; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D000431:Ethanol / Q000378:metabolism; D005285:Fermentation; D005947:Glucose / Q000172:deficiency / Q000378:metabolism; D008965:Molasses / Q000382:microbiology*; D011494:Protein Kinases / Q000172:deficiency / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism; D013312:Stress, Physiological; D013395:Sucrose / Q000378:metabolism*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism
chemical_list: D004268:DNA-Binding Proteins; C081935:MSN2 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D014157:Transcription Factors; D000431:Ethanol; D013395:Sucrose; D011494:Protein Kinases; C410736:Rim15 protein, S cerevisiae; D005947:Glucose
keywords: Alcoholic fermentation; Msn2p; Rim15p; Saccharomyces cerevisiae; Sake yeast; Stress response; Sucrose utilization; Sugarcane molasses