title: 3D Echo pilot study of geometric left ventricular changes after acute myocardial infarction.
abstract: BACKGROUND
  Left ventricular remodeling (LVR) after AMI characterizes a factor of poor prognosis. There is little information in the literature on the LVR analyzed with three-dimensional echocardiography (3D ECHO).
  
  
  OBJECTIVE
  To analyze, with 3D ECHO, the geometric and volumetric modifications of the left ventricle (VE) six months after AMI in patients subjected to percutaneous primary treatment.
  
  
  METHODS
  Prospective study with 3D ECHO of 21 subjects (16 men, 56 ± 12 years-old), affected by AMI with ST segment elevation. The morphological and functional analysis (LV) with 3D ECHO (volumes, LVEF, 3D sphericity index) was carried out up to seven days and six months after the AMI. The LVR was considered for increase > 15% of the end diastolic volume of the LV (LVEDV) six months after the AMI, compared to the LVEDV up to seven days from the event.
  
  
  RESULTS
  Eight (38%) patients have presented LVR. Echocardiographic measurements (n = 21 patients): I- up to seven days after the AMI: 1- LVEDV: 92.3 ± 22.3 mL; 2- LVEF: 0.51 ± 0.01; 3- sphericity index: 0.38 ± 0.05; II- after six months: 1- LVEDV: 107.3 ± 26.8 mL; 2- LVEF: 0.59 ± 0.01; 3- sphericity index: 0.31 ± 0.05. Correlation coefficient (r) between the sphericity index up to seven days after the AMI and the LVEDV at six months (n = 8) after the AMI: r: 0.74, p = 0.0007; (r) between the sphericity index six months after the AMI and the LVEDV at six months after the AMI: r: 0.85, p < 0.0001.
  
  
  CONCLUSIONS
  In this series, LVR has been observed in 38% of the patients six months after the AMI. The three-dimensional sphericity index has been associated to the occurrence of LVR.
authors.affiliation: Hospital Israelita Albert Einstein, São Paulo, SP - Brazil. mlvieira@cardiol.br
authors.forename: Marcelo Luiz Campos
authors.initials: ML
authors.lastname: Vieira
authors.forename: Wercules Antonio
authors.initials: WA
authors.lastname: Oliveira
authors.forename: Adriana
authors.initials: A
authors.lastname: Cordovil
authors.forename: Ana Clara Tude
authors.initials: AC
authors.lastname: Rodrigues
authors.forename: Cláudia Gianini
authors.initials: CG
authors.lastname: Mônaco
authors.forename: Tânia
authors.initials: T
authors.lastname: Afonso
authors.forename: Edgar Bezerra
authors.initials: EB
authors.lastname: Lira Filho
authors.forename: Marco
authors.initials: M
authors.lastname: Perin
authors.forename: Cláudio Henrique
authors.initials: CH
authors.lastname: Fischer
authors.forename: Samira Saady
authors.initials: SS
authors.lastname: Morhy
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy; D015588:Observer Variation; D009929:Organ Size; D010865:Pilot Projects; D011379:Prognosis; D011446:Prospective Studies; D012016:Reference Values; D015203:Reproducibility of Results; D020257:Ventricular Remodeling / Q000502:physiology*