title: Nongenital human papillomavirus disease.
abstract: Human papillomavirus (HPV) is the most common viral cause of cancer, and is responsible for 5% of cancers worldwide. Following demonstration of the causative link between HPV and cervical cancer, HPV has been shown to be associated with several anogenital malignancies and with oral pharyngeal cancers. HPV-related anal and oral pharyngeal disease is rising in incidence and includes anal warts and neoplasia, recurrent respiratory papillomatosis, and oral pharyngeal neoplasia. This article presents an overview of the epidemiology, clinical manifestations, diagnosis, and treatment of nongenital HPV-related disease.
authors.affiliation: Department of Family Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA. emayea@lsuhsc.edu
authors.forename: E J
authors.initials: EJ
authors.lastname: Mayeaux
authors.forename: Michelle J
authors.initials: MJ
authors.lastname: Khan
mesh_terms: D001005:Anus Neoplasms / Q000517:prevention & control / Q000628:therapy / Q000821:virology*; D002278:Carcinoma in Situ / Q000473:pathology / Q000821:virology; D005260:Female; D015658:HIV Infections / Q000150:complications; D006258:Head and Neck Neoplasms / Q000517:prevention & control / Q000821:virology*; D061809:Human Papillomavirus DNA Tests; D006801:Humans; D008297:Male; D018307:Neoplasms, Squamous Cell / Q000821:virology; D009959:Oropharyngeal Neoplasms / Q000517:prevention & control / Q000821:virology; D010212:Papilloma / Q000151:congenital / Q000517:prevention & control / Q000821:virology*; D030361:Papillomavirus Infections; D053918:Papillomavirus Vaccines; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology; D012140:Respiratory Tract Diseases / Q000151:congenital / Q000517:prevention & control / Q000821:virology*; D012725:Sexual Behavior
chemical_list: D053918:Papillomavirus Vaccines