title: Obstructive jaundice at the initial presentation in small-cell lung cancer.
abstract: Obstructive jaundice sometimes may develop in association with advanced small-cell lung cancer (SCLC); however, SCLC initially presenting with obstructive jaundice is rare. This report presents the cases of two SCLC patients with obstructive jaundice at the initial diagnosis. A 64-year-old male presented with obstructive jaundice due to a tumor at the head of the pancreas. He was diagnosed with SCLC by transbronchial biopsy from a lung tumor in the left upper lobe. Another 74-year-old male was admitted with jaundice due to a tumor in the porta hepatis. He was also diagnosed with SCLC by a fine-needle aspiration biopsy of a lung tumor in the left lower lobe. Both cases were successfully treated with systemic chemotherapy after endoscopic retrograde biliary drainage.
authors.affiliation: Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate school of Medicine, Dentistry and Pharmaceutical sciences, Okayama, Japan.
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Ochi
authors.forename: Nagio
authors.initials: N
authors.lastname: Takigawa
authors.forename: Masayuki
authors.initials: M
authors.lastname: Yasugi
authors.forename: Etsuji
authors.initials: E
authors.lastname: Ishida
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Kawamoto
authors.forename: Akihiko
authors.initials: A
authors.lastname: Taniguchi
authors.forename: Daijiro
authors.initials: D
authors.lastname: Harada
authors.forename: Eiko
authors.initials: E
authors.lastname: Hayashi
authors.forename: Hiroko
authors.initials: H
authors.lastname: Toda
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yanai
authors.forename: Mitsune
authors.initials: M
authors.lastname: Tanimoto
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Kiura
keywords: biliary obstruction; jaundice; metastasis; small-cell lung carcinoma