title: Relationship of adipokines (adiponectin, resistin and RBP4) with metabolic syndrome components in pubertal obese children.
abstract: OBJECTIVE
  To investigate the relationship between serum adiponectin, resistin and RBP4 levels and the components of metabolic syndrome.
  
  
  METHODS
  Serum adiponectin, resistin and RBP4 levels were detected and analyzed in 148 8-18-year-old Turkish obese pubertal children with/without metabolic syndrome.
  
  
  RESULTS
  Adiponectin and resistin concentrations were significantly inversely correlated with BMI standard deviation score, homeostatic model assessment insulin resistance, waist circumference, triglyceride levels and diastolic and systolic blood pressure, and were directly correlated with high-density lipoprotein cholesterol. RBP4 concentrations were directly correlated with homeostatic model assessment insulin resistance, waist circumference, triglyceride levels and diastolic and systolic blood pressure, and inversely correlated with high-density lipoprotein cholesterol.
  
  
  CONCLUSIONS
  Adiponectin, RBP4 and, in particular, resistin levels may be used as suitable predictive biomarkers of metabolic syndrome.
authors.affiliation: Department of Pediatrics, Division of Endocrinology, Şişli Etfal Education & Training Hospital, 34371 Istanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Boyraz
authors.forename: Ferhat
authors.initials: F
authors.lastname: Cekmez
authors.forename: Abdulbaki
authors.initials: A
authors.lastname: Karaoğlu
authors.forename: Peyami
authors.initials: P
authors.lastname: Cinaz
authors.forename: Mustafa
authors.initials: M
authors.lastname: Durak
authors.forename: Aysun
authors.initials: A
authors.lastname: Bideci
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D015992:Body Mass Index; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000503:physiopathology; D009765:Obesity / Q000097:blood* / Q000503:physiopathology; D011627:Puberty / Q000097:blood*; D052243:Resistin / Q000097:blood*; D054839:Retinol-Binding Proteins, Plasma / Q000378:metabolism*; D014421:Turkey
chemical_list: D052242:Adiponectin; D015415:Biomarkers; D001786:Blood Glucose; C101326:RBP4 protein, human; D052243:Resistin; D054839:Retinol-Binding Proteins, Plasma