title: Elevated testosterone levels in HIV-infected men: case report and a retrospective chart review.
abstract: Little is known about HIV-infected patients with serum testosterone levels in high normal to elevated ranges. An HIV-infected patient with hepatitis C and unexplained high serum testosterone levels prompted a retrospective chart review into the association of hepatitis C and serum testosterone levels greater than 1000 ng/mL in our clinic. The charts of 1419 male HIV patients were reviewed. Out of 1419 patients, 159 (11%) met the criteria for data analysis. A total of 8 patients had serum testosterone levels greater than 1000 ng/mL. There was no significant correlation between hepatitis C antibody positivity or presence of hepatitis C viremia as measured by viral load, nor was there any significant correlation with CD4+ cell counts. We found a weak positive association between years since reported diagnosis of HIV and high testosterone levels.
authors.affiliation: Weill Cornell Medical College, New York, NY, USA.
authors.forename: Veerawat
authors.initials: V
authors.lastname: Phongtankuel
authors.forename: Gregory
authors.initials: G
authors.lastname: Schrank
authors.forename: Erica N
authors.initials: EN
authors.lastname: Campbell
authors.forename: Carol
authors.initials: C
authors.lastname: Holtzman
authors.forename: John P
authors.initials: JP
authors.lastname: Gaughan
authors.forename: Mary
authors.initials: M
authors.lastname: van den Berg-Wolf
mesh_terms: D000328:Adult; D060085:Coinfection / Q000097:blood* / Q000821:virology*; D015658:HIV Infections / Q000097:blood* / Q000821:virology; D006526:Hepatitis C / Q000097:blood / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D013739:Testosterone / Q000097:blood*
chemical_list: D013739:Testosterone
keywords: HIV/hepatitis C coinfection; high serum testosterone levels