title: Two cases of complete hydatidiform mole and coexistent live fetus.
abstract: The aim of this study was to report the clinical features, management, and outcome of complete hydatidiform mole with a coexisting viable fetus. Two cases are reported. In both cases ultrasound examination demonstrated a normally growing live fetus alongside a normal placenta and an additional intrauterine echogenic mass with features of hydatidiform mole. The hCG levels were significantly increased and fetal karyotypes were normal. A cesarean section performed at 28 weeks' gestation in the first case and at 26 weeks' gestation in the second one resulted in the delivery of live normal infant and two adjoining placentas in both cases. Microscopic examination of the abnormal placentas confirmed complete hydatidiform mole. The babies did well and serial maternal serum hCG levels showed a declining trend and were undetectable by a few months after delivery. Continuation of a twin pregnancy with complete hydatidiform mole (CHMF) is an acceptable option. There is, although, an increased risk of developing maternal and fetal complications. Close surveillance of an ongoing pregnancy is compulsory to detect potential early signs of complications.
authors.affiliation: Obstetrics, Gynaecology and Neonatology, University of Bari, Bari, Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Vimercati
authors.forename: Alessandra Caterina
authors.initials: AC
authors.lastname: de Gennaro
authors.forename: Isabella
authors.initials: I
authors.lastname: Cobuzzi
authors.forename: Silvana
authors.initials: S
authors.lastname: Grasso
authors.forename: Marinella
authors.initials: M
authors.lastname: Abruzzese
authors.forename: Fabiana Divina
authors.initials: FD
authors.lastname: Fascilla
authors.forename: Gennaro
authors.initials: G
authors.lastname: Cormio
authors.forename: Luigi
authors.initials: L
authors.lastname: Selvaggi
keywords: complete hydatidiform mole; gestational trophoblastic disease; twin pregnancy