title: Prevalence of Campylobacter spp. relative to other enteric pathogens in grow-finish pigs with diarrhea.
abstract: Salmonella spp., Lawsonia intracellularis, and Brachyspira spp. are pathogens commonly associated with diarrhea in growing and finishing pigs. Brachyspira spp. infection has recently reemerged as a significant concern due to an increase in the incidence of swine dysentery; however, the mechanisms underlying this increase in dysentery remain largely unknown. Pigs are also well-recognized as potential carriers of Campylobacter spp., particularly Campylobacter coli, yet enteric disease in swine associated with infection by these bacteria is considered uncommon and diagnosis has historically been based upon exclusion of other causes. Accordingly, Campylobacter culture is often excluded in routine diagnostic testing of cases of porcine enterocolitis and the incidence of infection is therefore largely unknown. In this study, feces from 155 cases of clinical diarrhea in grow-finish pigs submitted to the Iowa State University Veterinary Diagnostic Laboratory were cultured for Campylobacter spp. in addition to other testing as indicated for routine diagnostic investigation. Campylobacter culture was positive from 82.6% (128/155) of samples with C. coli accounting for 75% of isolates and Campylobacter jejuni for the remaining 25%. In 14.8% (23/155) of cases a Campylobacter spp. was the sole infectious agent detected; however, there was no association with any particular Campylobacter spp. Interestingly, for those cases with a laboratory diagnosis of Brachyspira-associated disease, 100% (15/15) were also culture positive for Campylobacter spp. suggesting a possible interrelationship between these bacteria in the pig gut. No association was noted between Campylobacter culture results and infection with either Salmonella spp. or L. intracellularis.
authors.affiliation: Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA. burrough@iastate.edu
authors.forename: Eric
authors.initials: E
authors.lastname: Burrough
authors.forename: Samantha
authors.initials: S
authors.lastname: Terhorst
authors.forename: Orhan
authors.initials: O
authors.lastname: Sahin
authors.forename: Qijing
authors.initials: Q
authors.lastname: Zhang
mesh_terms: D000818:Animals; D002169:Campylobacter Infections / Q000382:microbiology* / Q000662:veterinary*; D017000:Campylobacter coli / Q000302:isolation & purification; D016123:Campylobacter jejuni / Q000302:isolation & purification*; D003967:Diarrhea / Q000382:microbiology* / Q000662:veterinary*; D005243:Feces / Q000382:microbiology*; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology*; D014481:United States
keywords: Brachyspira; Campylobacter; Diarrhea; Porcine