title: JMML patient-derived iPSCs induce new hypotheses.
abstract: In this issue of Blood, Gandre-Babbe et al have, in part, overcome the obstacle of validating the molecular underpinnings of juvenile myelomonocytic leukemia (JMML) with the generation of induced pluripotent stem cells (iPSCs) from individuals with JMML.
authors.affiliation: Indiana University School of Medicine.
authors.forename: Rebecca J
authors.initials: RJ
authors.lastname: Chan
authors.forename: Mervin C
authors.initials: MC
authors.lastname: Yoder
mesh_terms: D005260:Female; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000378:metabolism*; D054429:Leukemia, Myelomonocytic, Juvenile / Q000378:metabolism*; D008297:Male; D020125:Mutation, Missense; D014411:Neoplastic Stem Cells / Q000378:metabolism*; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1 / Q000378:metabolism*
chemical_list: C516607:PTPN1 protein, human; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1