title: Paracoccidioides lutzii sp. nov.: biological and clinical implications.
abstract: Paracoccidioides lutzii, formerly known as 'Pb01-like' strains in the P. brasiliensis complex, is proposed as a new species based on phylogenetic and comparative genomics data, recombination analysis, and morphological characteristics. Conidia of P. lutzii are elongated, different from those of P. brasiliensis. P. lutzii occurs in the central and northern regions of Brazil. Studies comparing P. brasiliensis and P. lutzii may have significant clinical consequences for the diagnosis and treatment of paracoccidioidomycosis.
authors.affiliation: Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, DF, Brazil.
authors.forename: Marcus de Melo
authors.initials: Mde M
authors.lastname: Teixeira
authors.forename: Raquel Cordeiro
authors.initials: RC
authors.lastname: Theodoro
authors.forename: Fabiana Freire Mendes de
authors.initials: FF
authors.lastname: Oliveira
authors.forename: Gabriel Capella
authors.initials: GC
authors.lastname: Machado
authors.forename: Rosane Christine
authors.initials: RC
authors.lastname: Hahn
authors.forename: Eduardo
authors.initials: E
authors.lastname: Bagagli
authors.forename: Gioconda
authors.initials: G
authors.lastname: San-Blas
authors.forename: Maria Sueli
authors.initials: MS
authors.lastname: Soares Felipe
mesh_terms: D001938:Brazil; D016000:Cluster Analysis; D005656:Fungal Proteins / Q000235:genetics; D006801:Humans; D008853:Microscopy; D008969:Molecular Sequence Data; D010228:Paracoccidioides / Q000145:classification* / Q000166:cytology / Q000235:genetics / Q000302:isolation & purification*; D010229:Paracoccidioidomycosis / Q000382:microbiology; D010802:Phylogeny; D017422:Sequence Analysis, DNA
chemical_list: D005656:Fungal Proteins
keywords: Paracoccidioides brasiliensis; Paracoccidioides lutzii; paracoccidioidomycosis; speciation