title: Nickel-catalyzed alkyne annulation by anilines: versatile indole synthesis by C-H/N-H functionalization.
abstract: Versatile nickel catalysts enabled the step-economical synthesis of decorated indoles through alkyne annulations with anilines bearing removable directing groups. The C-H/N-H activation strategy efficiently occurred in the absence of any metal oxidants and with excellent selectivities.
authors.affiliation: Institut fuer Organische und Biomolekulare Chemie, Georg-August-Universitaet, Tammannstrasse 2, 37077 Goettingen, Germany.
authors.forename: Weifeng
authors.initials: W
authors.lastname: Song
authors.forename: Lutz
authors.initials: L
authors.lastname: Ackermann
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*
chemical_list: D000480:Alkynes; D000814:Aniline Compounds; D007211:Indoles; D009942:Organometallic Compounds; D009532:Nickel; C023650:aniline