title: [Surgical management of descending necrotizing mediastinitis].
abstract: BACKGROUND
  Descending necrotizing mediastinitis (DNM) is a serious infection which occurs as a complication of oropharyngeal infection. Its surgical management and the routine transthoracic approach remain controversial. In this article we report our experience in the management of this disease, and review the different surgical approaches that have been reported in the medical literature.
  
  
  METHODS
  A retrospective review was made of the clinical records of 29 patients treated between 1988 and 2009. Several demographic variables were analyzed, origin of the initial infection, stage of the disease according to Endo's classification, surgical technique and outcome.
  
  
  RESULTS
  Surgical treatment consisted of both cervical and mediastinal drainage and radical debridement. The mediastinal drainage was made through a transcervical approach in 10 cases and transthoracic in 19, depending on the extent of the mediastinitis. The outcome was satisfactory in 24 patients and 5 died (mortality 17.2%).
  
  
  CONCLUSIONS
  According to our results and the conclusions of the main authors, we recommend a prompt and aggressive surgery with a transthoracic approach in cases of widespread DNM.
authors.affiliation: Servicio de Cirugía Torácica, Hospital Virgen de las Nieves, Granada, España. Electronic address: carala55@yahoo.es.
authors.forename: Clara Isabel
authors.initials: CI
authors.lastname: Bayarri Lara
authors.forename: Sebastián
authors.initials: S
authors.lastname: Sevilla López
authors.forename: Abel
authors.initials: A
authors.lastname: Sánchez-Palencia Ramos
authors.forename: Amira
authors.initials: A
authors.lastname: Alkourdi Martínez
authors.forename: Francisco
authors.initials: F
authors.lastname: Hernández Escobar
authors.forename: Florencio
authors.initials: F
authors.lastname: Quero Valenzuela
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Ruiz Zafra
authors.forename: Antonio
authors.initials: A
authors.lastname: Cueto Ladrón de Guevara
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000473:pathology* / Q000601:surgery*; D008482:Mediastinum / Q000473:pathology* / Q000601:surgery*; D008875:Middle Aged; D009336:Necrosis / Q000601:surgery; D012189:Retrospective Studies; D019616:Thoracic Surgical Procedures / Q000379:methods; D055815:Young Adult
keywords: Descending necrotizing mediastinitis; Mediastinitis necrosante descendente; Mediastino; Mediastinum; Surgical treatment; Tratamiento quirúrgico