title: [Cohort Study in Primary Health Care on the Evolution of Patients with Prediabetes (PREDAPS): basis and methodology].
abstract: The PREDAPS study aims to determine the risk of developing diabetes and the risk of vascular complications in patients with prediabetes and identify factors associated with those risks. It is a prospective observational study of a cohort of 1184 subjects with prediabetes and another cohort of 838 subjects with no alterations in glucose metabolism. The data at baseline were obtained from patients attending primary care centers in Spain throughout 2012. Subjects with prediabetes were classified into three groups: those who had only altered the fasting blood glucose levels -between 100 and 125mg/dl-, those who had only altered the HbA1c level -between 5.7 and 6.4% - and those who had altered both parameters. Information on sociodemographic characteristics, personal and family history, lifestyle and drug therapy was obtained from medical records and the interview with the doctor in the consultation. It was also performed a physical examination to determine weight, height, waist circumference and blood pressure were performed and blood and urine analysis. The PREDAPS study may help to reduce uncertainty in individual prevention strategies in subjects with prediabetes. Annual monitoring of patients recruited for five years will enable to know the risk of developing diabetes type 2 and the risk of macro-and microvascular complications in the three groups of subjects with prediabetes and determine the factors associated with those risks.
authors.affiliation: Centro de Salud Martín de Vargas, Madrid, España.
authors.forename: Rosario
authors.initials: R
authors.lastname: Serrano
authors.forename: F Javier
authors.initials: FJ
authors.lastname: García-Soidán
authors.forename: Alicia
authors.initials: A
authors.lastname: Díaz-Redondo
authors.forename: Sara
authors.initials: S
authors.lastname: Artola
authors.forename: Josep
authors.initials: J
authors.lastname: Franch
authors.forename: Javier
authors.initials: J
authors.lastname: Díez
authors.forename: Lourdes
authors.initials: L
authors.lastname: Carrillo
authors.forename: Patxi
authors.initials: P
authors.lastname: Ezkurra
authors.forename: J Manuel
authors.initials: JM
authors.lastname: Millaruelo
authors.forename: Mateu
authors.initials: M
authors.lastname: Seguí
authors.forename: F Javier
authors.initials: FJ
authors.lastname: Sangrós
authors.forename: Juan
authors.initials: J
authors.lastname: Martínez-Candela
authors.forename: Pedro
authors.initials: P
authors.lastname: Muñoz
authors.forename: Albert
authors.initials: A
authors.lastname: Goday
authors.forename: Enrique
authors.initials: E
authors.lastname: Regidor
mesh_terms: D000328:Adult; D015331:Cohort Studies; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology* / Q000517:prevention & control; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D011236:Prediabetic State / Q000097:blood / Q000145:classification / Q000175:diagnosis*; D011320:Primary Health Care; D011446:Prospective Studies; D018570:Risk Assessment / Q000379:methods; D013030:Spain; D055105:Waist Circumference
chemical_list: D006442:Glycated Hemoglobin