title: Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow.
abstract: A DNA molecule is rotated under a transversal electric field to be perpendicular to a longitudinal, multicomponent microfluidic flow. Positioning the interface allows us to control DNA unzipping with spatio-temporal resolution. This demonstrates that a microfluidic gradient can be applied at the single molecule level for a dynamic intramolecular stimulation.
authors.affiliation: Department of Chemistry, Ecole Normale Supérieure, 75005 Paris, France.
authors.forename: Naresh K
authors.initials: NK
authors.lastname: Mani
authors.forename: Sergii
authors.initials: S
authors.lastname: Rudiuk
authors.forename: Damien
authors.initials: D
authors.lastname: Baigl
mesh_terms: D004247:DNA / Q000737:chemistry*; D046210:Microfluidic Analytical Techniques
chemical_list: D004247:DNA