title: Regeneration potential of adult cardiac myocytes.
abstract: Although adult cardiac myocytes (CMs) have very little proliferative potential, fetal CMs divide robustly. The mechanisms underlying the post-mitotic state of CMs are poorly understood; however, recently Mahmoud et al. identified a homeodomain transcription factor, Meis1, which controls postnatal CM cell cycle.
authors.affiliation: Department of Medicine, Center for Cardiovascular Biology, Institute for Stem Cell Research, University of Washington School of Medicine, Seattle, WA 98195, USA.
authors.forename: Kyohei
authors.initials: K
authors.lastname: Oyama
authors.forename: Danny
authors.initials: D
authors.lastname: El-Nachef
authors.forename: W Robb
authors.initials: WR
authors.lastname: MacLellan
mesh_terms: D000818:Animals; D059447:Cell Cycle Checkpoints; D005260:Female; D018398:Homeodomain Proteins / Q000378:metabolism*; D008297:Male; D032383:Myocytes, Cardiac / Q000166:cytology* / Q000378:metabolism*; D009363:Neoplasm Proteins / Q000378:metabolism*
chemical_list: D018398:Homeodomain Proteins; D009363:Neoplasm Proteins