title: Genetic profiles in ischaemic stroke.
abstract: Stroke represents a clinical syndrome rather than a single disease. A number of stroke subtypes can be distinguished based on careful phenotyping, with each of these having distinct and overlapping risk factor profiles. Recent evidence has suggested that genetics plays an important part in stroke risk, with at least 2 genes specific to stroke risk directly now having been identified. This review will explore our current understanding of the genetics underlying stroke risk and whether this information is currently useful in a clinical setting for patient benefit.
authors.affiliation: Stroke and Dementia Research Centre, St George's, University of London, Cranmer Terrace, Tooting, London, SW17 0RE, UK. sbevan@sgul.ac.uk
authors.forename: Steve
authors.initials: S
authors.lastname: Bevan
authors.forename: Hugh S
authors.initials: HS
authors.lastname: Markus
mesh_terms: D002545:Brain Ischemia / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D012307:Risk Factors