title: [Long-term results of combined treatment of soft tissue sarcoma with the use of intraoperative radiotherapy].
abstract: This retrospective study of long-term results of combined treatment of soft tissue sarcoma with the use of intraoperative radiotherapy (IORT) included 171 patients. Controls received adjuvant distant gamma-therapy (n = 57) or surgical treatment (n = 171). IORT significantly improved 5 year general (p = 0.025) and relapse-free (p < 0.025) survival rate and the same parameters in patients with a tumour larger than 5 cm (p = 0.0001). The intergroup difference regardless of tumour differentiation was insignificant (p =0.33), but survival rate tended to decrease in patients with moderately and weakly differentiated sarcomas (G2-3). It is concluded that combined treatment with IORT may be used as an alternative method for the treatment of moderately and weakly differentiated sarcomas.
authors.forename: P A
authors.initials: PA
authors.lastname: Ott
authors.forename: A V
authors.initials: AV
authors.lastname: Provalov
authors.forename: A V
authors.initials: AV
authors.lastname: Vazhenin
authors.forename: E A
authors.initials: EA
authors.lastname: Nadvikova
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Kandakova
authors.forename: E G
authors.initials: EG
authors.lastname: Zabolotskaia
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D011878:Radiotherapy / Q000295:instrumentation / Q000379:methods*; D012189:Retrospective Studies; D012509:Sarcoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome