title: Constituents of Caryopteris incana and their antibacterial activity.
abstract: Two new compounds named caryocanolide (1), and caryocanoside A (2), together with nine known compounds (3-11) were isolated from the whole plant of Caryopteris incana. These structures were determined mainly on the basis of 2D nuclear magnetic resonance and high resolution fast atom bombardment mass spectroscopy data. Furthermore, the isolated compounds (1, 2, 4-11) were tested for their antibacterial activity. Compound 1 exhibited moderate antimicrobial activity against Bacillus subtilis with a minimum inhibitory concentration value of 35.7 μM.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-Cho, Tokushima, 770-8514, Japan, yosikawa@ph.bunri-u.ac.jp.
authors.forename: Kazuko
authors.initials: K
authors.lastname: Yoshikawa
authors.forename: Akinori
authors.initials: A
authors.lastname: Harada
authors.forename: Kanako
authors.initials: K
authors.lastname: Iseki
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Hashimoto
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects / Q000254:growth & development; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D015394:Molecular Structure; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal; D016339:Spectrometry, Mass, Fast Atom Bombardment; D029648:Verbenaceae / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts