title: Pd-catalyzed C-S activation for [3 + 3] annulation of 2-(methylthio)benzofuran-3-carboxylates and 2-hydroxyphenylboronic acids: synthesis of coumestan derivatives.
abstract: Pd-catalytic C-S activation was successfully applied to initiate the cross-coupling of (2-methylthio-3-ester)benzofurans with 2-hydroxyphenylboronic acids and sequential intramolecular transesterification process under Liebeskind-Srogl conditions. Thus, a novel [3 + 3] annulation strategy for efficient synthesis of coumestan derivatives has been developed from readily available starting materials.
authors.affiliation: Department of Chemistry, Northeast Normal University, Changchun 130024, PR China.
authors.forename: Jingxin
authors.initials: J
authors.lastname: Liu
authors.forename: Yingjie
authors.initials: Y
authors.lastname: Liu
authors.forename: Wenting
authors.initials: W
authors.lastname: Du
authors.forename: Ying
authors.initials: Y
authors.lastname: Dong
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.forename: Mang
authors.initials: M
authors.lastname: Wang
mesh_terms: D001572:Benzofurans / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D003374:Coumarins / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D001572:Benzofurans; D001897:Boronic Acids; D003374:Coumarins; D009942:Organometallic Compounds; D010165:Palladium; C505898:coumestan