title: Effects of the pharmaceutical fluoxetine in spiked-sediments on feeding activity and growth of the polychaete Capitella teleta.
abstract: The marine-estuarine polychaete Capitella is an indicator of organic pollution and plays important roles in sewage waste cycling. The antidepressant fluoxetine can be accumulated in streams and sewage effluents and it could pose a hazard to infauna. Effects of fluoxetine on feeding and growth of Capitella teleta were investigated through the exposure to 0, 0.001, 0.03, 0.3 and 3.3 μg/g dry weight sediment-spiked fluoxetine during 18 days. No effects of fluoxetine concentrations were observed on egestion rates, body weight and size-specific egestion rates. Fluoxetine favoured the occurrence of males with abnormal genital spines. This suggests that fluoxetine can have important reproductive implications. Further studies are recommended to assess potential detrimental effects on benthic infauna inhabiting close to sewage treatment plants.
authors.affiliation: Laboratorio de Invertebrados Bentónicos, Unidad Académica Mazatlán, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Apdo. Postal 811, Mazatlán, Sinaloa 82000, Mexico. nuri@ola.icmyl.unam.mx
authors.forename: Nuria
authors.initials: N
authors.lastname: Méndez
authors.forename: Silvia
authors.initials: S
authors.lastname: Lacorte
authors.forename: Carlos
authors.initials: C
authors.lastname: Barata
mesh_terms: D000818:Animals; D004784:Environmental Monitoring; D005247:Feeding Behavior; D005473:Fluoxetine / Q000032:analysis / Q000633:toxicity*; D019015:Geologic Sediments / Q000737:chemistry; D011077:Polychaeta / Q000033:anatomy & histology / Q000187:drug effects* / Q000502:physiology; D018675:Toxicity Tests; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity*
chemical_list: D014874:Water Pollutants, Chemical; D005473:Fluoxetine
keywords: Abnormalities; Bioassays; Capitella; Deposit feeder; Growth; Pharmaceuticals; Polychaetes; Prozac; Sediment processing