title: The correlation between expression of synuclein-gamma, glucose transporter-1, and survival outcomes in endometrioid endometrial carcinoma.
abstract: OBJECTIVE
  To evaluate the correlation between immunohistochemical expression of synuclein-gamma, glucose transporter-1, and survival outcomes in endometrioid endometrial carcinoma.
  
  
  METHODS
  A tissue microarray was constructed using formalinfixed, paraffin-embedded tissue that included 23 early and 18 advanced cases. The intensity and area of the immunohistochemical reactions were evaluated using the semi-quantitative scoring system.
  
  
  RESULTS
  Synuclein-y expression was higher in the advanced stage, although it was not statistically significant (p = 0.51). Glucose transporter-1 was overexpressed in the advanced stage (p = 0.01). Synuclein-gamma (score = 0 vs > 0) and glucose transporter-1 (score < or = 7 vs > 7) did not show any differences in overall survival (p = 0.54, p = 0.48) and disease-free survival (p = 0.61, p = 0.14).
  
  
  CONCLUSIONS
  In this study the expression of synuclein-y and glucose transporter-1 were not considered to be a prognostic factor and were not related with survival outcomes in endometrioid endometrial carcinoma.
authors.affiliation: Gynecologic Cancer Center, Kyungpook National University Medical Center, Daegu, Republic of Korea.
authors.forename: D G
authors.initials: DG
authors.lastname: Hong
authors.forename: N Y
authors.initials: NY
authors.lastname: Park
authors.forename: G O
authors.initials: GO
authors.lastname: Chong
authors.forename: Y L
authors.initials: YL
authors.lastname: Cho
authors.forename: I S
authors.initials: IS
authors.lastname: Park
authors.forename: M J
authors.initials: MJ
authors.lastname: Jeong
authors.forename: J Y
authors.initials: JY
authors.lastname: Park
authors.forename: Y S
authors.initials: YS
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D018269:Carcinoma, Endometrioid / Q000737:chemistry / Q000401:mortality* / Q000473:pathology; D016889:Endometrial Neoplasms / Q000737:chemistry / Q000401:mortality* / Q000473:pathology; D005260:Female; D051272:Glucose Transporter Type 1 / Q000032:analysis*; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000032:analysis*; D009367:Neoplasm Staging; D046888:Tissue Array Analysis; D051845:gamma-Synuclein / Q000032:analysis*
chemical_list: D051272:Glucose Transporter Type 1; D009363:Neoplasm Proteins; C104249:SNCG protein, human; D051845:gamma-Synuclein