title: Odorless isocyanide chemistry: an integrated microfluidic system for a multistep reaction sequence.
abstract: Can't smell this: An integrated continuous-flow microfluidic setup enables in situ generation, extraction, separation, and reaction of foul-smelling isocyanides with little exposure to the surroundings. Isocyanides were generated by dehydration of the corresponding N-substituted formamides, and several representative isocyanide-based organic reactions were successfully performed. DIPEA = N,N-diisopropylethylamine.
authors.affiliation: Department of Chemical Engineering, Pohang University of Science and Technology, POSTECH, Pohang, 790-784, Korea.
authors.forename: Siddharth
authors.initials: S
authors.lastname: Sharma
authors.forename: Ram Awatar
authors.initials: RA
authors.lastname: Maurya
authors.forename: Kyoung-Ik
authors.initials: KI
authors.lastname: Min
authors.forename: Guan-Young
authors.initials: GY
authors.lastname: Jeong
authors.forename: Dong-Pyo
authors.initials: DP
authors.lastname: Kim
keywords: continuous flow; isocyanides; microreactors; multi-component reactions; organometallics