title: A simple, fast and highly sensitive assay for the detection of telomerase activity.
abstract: A highly sensitive and rapid PCR-free telomerase activity assay has been developed that uses SYBR Green intercalation into the G-quadruplex structures in the presence of K(+).
authors.affiliation: BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Major of Nanobiotechnology, University of Science and Technology, Gwahangno, Yuseong, Daejeon 305-806, Republic of Korea.
authors.forename: Quang Huy
authors.initials: QH
authors.lastname: Quach
authors.forename: Juyeon
authors.initials: J
authors.lastname: Jung
authors.forename: Hyeran
authors.initials: H
authors.lastname: Kim
authors.forename: Bong Hyun
authors.initials: BH
authors.lastname: Chung
mesh_terms: D000880:Anthraquinones / Q000494:pharmacology; D052160:Benzothiazoles; D002460:Cell Line; D003959:Diamines; D054856:G-Quadruplexes; D057809:HEK293 Cells; D006367:HeLa Cells; D056945:Hep G2 Cells; D006801:Humans; D009930:Organic Chemicals / Q000737:chemistry / Q000378:metabolism; D011188:Potassium / Q000737:chemistry; D011804:Quinolines; D013329:Structure-Activity Relationship; D019098:Telomerase / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000378:metabolism*
chemical_list: D000880:Anthraquinones; D052160:Benzothiazoles; D003959:Diamines; D009930:Organic Chemicals; D011804:Quinolines; C098022:SYBR Green I; C116107:2,6-diaminoanthraquinone; D019098:Telomerase; D011188:Potassium