title: Synthesis and properties of BF2-3,3'-dimethyldiarylazadipyrromethene near-infrared fluorophores.
abstract: The first synthesis of both organic and aqueous soluble BF2 chelated 3,3'-dimethyl-5,5'-diarylazadipyrromethenes has been achieved. The fluorophores are emissive in organic and aqueous solvents with high quantum yields in the key biological near-infrared (NIR) spectral region of 675-700 nm. Following efficient cellular uptake from aqueous media the fluorophore can be readily visualized with confocal microscopy.
authors.affiliation: School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.
authors.forename: Dan
authors.initials: D
authors.lastname: Wu
authors.forename: Donal F
authors.initials: DF
authors.lastname: O'Shea
mesh_terms: D001372:Aza Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D005453:Fluorescence; D018613:Microscopy, Confocal; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D019265:Spectroscopy, Near-Infrared / Q000379:methods*
chemical_list: D001372:Aza Compounds; D001896:Boron Compounds; D011758:Pyrroles; D012997:Solvents; C579460:boron difluoride