title: [Estimation of activity of bis-netropsin derivatives based on a model of an experimental cutaneous herpes simplex virus disease of guinea pigs].
abstract: Using the model of an experimental cutaneous infection of guinea pig males caused by herpes simple virus type 1, it is shown that application of dimerico derivatives of netropsin Lys-bis Nt and 15Lys-bis Nt in the form of polietilenglicol-based ointment suppresses viral infection more effectively than acyclovir.
authors.forename: V L
authors.initials: VL
authors.lastname: andronova
authors.forename: S L
authors.initials: SL
authors.lastname: Grokhovskiĭ
authors.forename: A N
authors.initials: AN
authors.lastname: Surovaia
authors.forename: G V
authors.initials: GV
authors.lastname: Gurskiĭ
authors.forename: P G
authors.initials: PG
authors.lastname: Deriabin
authors.forename: D K
authors.initials: DK
authors.lastname: L'vov
authors.forename: G A
authors.initials: GA
authors.lastname: Galegov
mesh_terms: D000212:Acyclovir / Q000494:pharmacology; D000287:Administration, Topical; D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D004195:Disease Models, Animal; D006168:Guinea Pigs; D006561:Herpes Simplex / Q000188:drug therapy* / Q000473:pathology; D018259:Herpesvirus 1, Human; D008297:Male; D009429:Netropsin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D009824:Ointments
chemical_list: D000998:Antiviral Agents; D009824:Ointments; D009429:Netropsin; D000212:Acyclovir