title: Indian tick typhus presenting with gangrene: a case report from an urban slum of Delhi.
abstract: Indian Tick Typhus has been rarely reported in children from Delhi. A 10-y-old male child from Delhi presented with fever, non specific gastrointestinal symptoms, petechial rash and gangrene of all the toes. Possibility of rickettsial infection was entertained after the child failed to improve with best of the antibiotics. Sample for serology for rickettsial infection was sent and Doxycycline was started empirically. He became afebrile within 72 h of starting Doxycycline. Later, diagnosis of Indian Tick Typhus was confirmed on the basis of IgM positivity against Rickettsia conori. Possibility of rickettsial infection should be entertained in children with history of fever and skin rash, especially if the child fails to improve with a course of antibiotics and common infectious etiologies have been ruled out.
authors.affiliation: Department of Pediatrics, Chacha Nehru Bal Chikitsalaya (Affiliated with Maulana Azad Medical College), Geeta Colony, Delhi, India, manishkp75@yahoo.com.
authors.forename: Manish
authors.initials: M
authors.lastname: Kumar
authors.forename: Raghvendra
authors.initials: R
authors.lastname: Singh
authors.forename: Mukesh
authors.initials: M
authors.lastname: Yadav
mesh_terms: D001907:Boutonneuse Fever / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D002648:Child; D005734:Gangrene / Q000209:etiology; D006801:Humans; D007194:India; D008297:Male; D011204:Poverty Areas; D014034:Toes / Q000473:pathology*; D014504:Urban Health