title: Behavioural and metabolic characterisation of the low satiety phenotype.
abstract: Some individuals report weak appetite sensations and thus, have higher susceptibility to overeating. The aim of this study was (1) to evaluate the reliability of the satiety quotient (SQ), a marker of satiety efficiency; (2) to characterize the biopsychobehavioural profiles of individual presenting low satiety efficiency, i.e. the low satiety phenotype and (3) to document the impact of a weight loss program on these profiles. Sixty-nine obese men (BMI 33.6±3.0 kg/m², age 41.5±5.7 years) participated in a 16-week, non-restrictive weight loss intervention. Visual analog scales for appetite sensations in response to a test-meal were completed twice at baseline. Blood samples were collected before and during one test-meal. Questionnaires were administered before and after the intervention. The mean SQ showed good reliability (ICC=0.67). Baseline SQ scores tended to be negatively correlated with external hunger, anxiety and night eating symptoms (p<0.10). Moreover, the low satiety phenotype showed a lower cortisol response to the test-meal (p<0.05). The SQ seems to be a reliable marker of weaker appetite sensation responses. Stress/anxiety could be involved in the low satiety phenotype but did not influence the biopsychobehavioural changes in response to the intervention.
authors.affiliation: Faculty of Educational Sciences, Department of Physical Education, Laval University, Quebec, QC, Canada. vicky.drapeau@fse.ulaval.ca
authors.forename: V
authors.initials: V
authors.lastname: Drapeau
authors.forename: J
authors.initials: J
authors.lastname: Blundell
authors.forename: A R
authors.initials: AR
authors.lastname: Gallant
authors.forename: H
authors.initials: H
authors.lastname: Arguin
authors.forename: J-P
authors.initials: JP
authors.lastname: Després
authors.forename: B
authors.initials: B
authors.lastname: Lamarche
authors.forename: A
authors.initials: A
authors.lastname: Tremblay
mesh_terms: D000328:Adult; D001007:Anxiety / Q000503:physiopathology; D001066:Appetite / Q000502:physiology*; D001827:Body Height; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D004435:Eating / Q000523:psychology*; D006801:Humans; D006815:Hunger / Q000502:physiology; D008297:Male; D062407:Meals; D008875:Middle Aged; D009765:Obesity / Q000503:physiopathology; D010641:Phenotype; D011792:Quebec; D015203:Reproducibility of Results; D012527:Satiation / Q000502:physiology*; D011795:Surveys and Questionnaires; D015431:Weight Loss
keywords: Appetite control; Behaviours; Food intake; Hunger; Metabolic profile; Satiety