title: [Optimized treatment of a patient having rheumatoid arthritis and gout at the same time].
abstract: Biologic TNF alpha blocker medication was started for a patient having active rheumatoid arthritis, because the disease was unresponsive to conventional drugs and the patient also 'had reactive amyloidosis. Due to weakening efficiency and simultaneously occurring gout the medication was replaced by an IL-1 receptor blocker, which in addition to controlling rheumatoid arthritis also acts by suppressing gouty attacks. Finding an optimized drug combination for rheumatoid patients will become easier with the increasing number of biologic drugs functioning through different mechanisms of action.
authors.affiliation: HYKS, Sisätautien ja Reumatologian Klinikka Helingin Yliopisto, Klininen Laitos.
authors.forename: Dan
authors.initials: D
authors.lastname: Nordström
authors.forename: Marjatta
authors.initials: M
authors.lastname: Leirisalo-Repo
authors.forename: Tom
authors.initials: T
authors.lastname: Petterson
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D006073:Gout / Q000150:complications* / Q000188:drug therapy*; D006074:Gout Suppressants / Q000627:therapeutic use*; D006801:Humans; D017472:Receptors, Interleukin-1 / Q000037:antagonists & inhibitors*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D018501:Antirheumatic Agents; D006074:Gout Suppressants; D017472:Receptors, Interleukin-1; D014409:Tumor Necrosis Factor-alpha