title: Palladium-catalyzed oxidative aminocarbonylation: a new entry to amides via C-H activation.
abstract: A novel palladium-catalyzed oxidative aminocarbonylation reaction via C(sp(3))-H activation was established, which provides a convenient and general method for the construction of arylacetamides via the carbonylation reaction of alkyl aromatics and amines. By using this protocol, the marketed drug ibuprofen could be easily obtained.
authors.affiliation: State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
authors.forename: Pan
authors.initials: P
authors.lastname: Xie
authors.forename: Chungu
authors.initials: C
authors.lastname: Xia
authors.forename: Hanmin
authors.initials: H
authors.lastname: Huang