title: Rheumatoid arthritis vs osteoarthritis in patients receiving total knee arthroplasty: perioperative outcomes.
abstract: There is a paucity of data available on perioperative outcomes of patients undergoing total knee arthroplasty (TKA) for rheumatoid arthritis (RA). We determined differences in demographics and risk for perioperative adverse events between patients suffering from osteoarthritis (OA) versus RA using a population-based approach. Of 351,103 entries for patients who underwent TKA, 3.4% had a diagnosis of RA. RA patients were on average younger [RA: 64.3 years vs OA: 66.6 years; P<0.001] and more likely female [RA: 79.2% vs OA: 63.2%; P<0. 001]. The unadjusted rates of mortality and most major perioperative adverse events were similar in both groups, with the exception of infection [RA: 4.5% vs. OA: 3.8%; P<0.001]. RA was not associated with increased adjusted odds for combined adverse events.
authors.affiliation: Department of Anesthesiology, Hospital for Special Surgery, Weill Medical, College of Cornell University, New York, New York; Department of Anesthesiology, Perioperative Medicine and Intensive Care Medicine, Paracelsus Medical University, Salzburg, Salzburg, Austria.
authors.forename: Ottokar
authors.initials: O
authors.lastname: Stundner
authors.affiliation: Department of Anesthesiology, Hospital for Special Surgery, Weill Medical, College of Cornell University, New York, New York; Department of Anesthesiology, Perioperative Medicine and Intensive Care Medicine, Paracelsus Medical University, Salzburg, Salzburg, Austria.
authors.forename: Thomas
authors.initials: T
authors.lastname: Danninger
authors.affiliation: Department of Public Health, Division of Biostatistics and Epidemiology, Weill Medical College of Cornell University, New York, New York.
authors.forename: Ya-Lin
authors.initials: YL
authors.lastname: Chiu
authors.affiliation: Department of Public Health, Division of Biostatistics and Epidemiology, Weill Medical College of Cornell University, New York, New York.
authors.forename: Xuming
authors.initials: X
authors.lastname: Sun
authors.affiliation: Department of Rheumatology, Hospital for Special Surgery, Weill Medical, College of Cornell University, New York, New York.
authors.forename: Susan M
authors.initials: SM
authors.lastname: Goodman
authors.affiliation: Department of Rheumatology, Hospital for Special Surgery, Weill Medical, College of Cornell University, New York, New York.
authors.forename: Linda A
authors.initials: LA
authors.lastname: Russell
authors.affiliation: Department of Orthopaedic Surgery, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York.
authors.forename: Mark
authors.initials: M
authors.lastname: Figgie
authors.affiliation: Department of Anesthesiology, Perioperative Medicine and Intensive Care Medicine, Paracelsus Medical University, Salzburg, Salzburg, Austria.
authors.forename: Madhu
authors.initials: M
authors.lastname: Mazumdar
authors.affiliation: Department of Anesthesiology, Hospital for Special Surgery, Weill Medical, College of Cornell University, New York, New York.
authors.forename: Stavros G
authors.initials: SG
authors.lastname: Memtsoudis
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000601:surgery*; D019645:Arthroplasty, Replacement, Knee; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery*; D016896:Treatment Outcome
keywords: arthroplasty knee; osteoarthritis; outcomes research; rheumatoid arthritis