title: Catalytic synthesis and antioxidant activity of sulfated polysaccharide from Momordica charantia L.
abstract: Sulfated derivatives of polysaccharide from Momordica charantia L. (MCPS) with different degree of sulfation (DS) were synthesized by chlorosulfonic acid method with ionic liquids as solvent. Fourier transform infrared spectra and 13C nuclear magnetic resonance spectra indicated that C-6 substitution was predominant in MCPS compared with the C-2 position. Compared with the native polysaccharide from Momordica charantia L. (MCP), MCPS exhibited more excellent antioxidant activities in vitro, which indicated that sulfated modification could enhance antioxidant activities of MCP. Furthermore, high DS and moderate molecular weight could improve the antioxidant activities of polysaccharide.
authors.affiliation: Institute of Integrated Chinese and Western Medicine, School of Basic Medical Sciences, Lanzhou University, Lanzhou, 730000, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Liu
authors.forename: Tong
authors.initials: T
authors.lastname: Chen
authors.forename: Yan
authors.initials: Y
authors.lastname: Hu
authors.forename: Kexin
authors.initials: K
authors.lastname: Li
authors.forename: Liushui
authors.initials: L
authors.lastname: Yan
mesh_terms: D000975:Antioxidants; D008970:Molecular Weight; D029777:Momordica charantia; D010084:Oxidation-Reduction; D011134:Polysaccharides; D017550:Spectroscopy, Fourier Transform Infrared; D013431:Sulfates
chemical_list: D000975:Antioxidants; D011134:Polysaccharides; D013431:Sulfates
keywords: Momordica charantia L.; antioxidant; polysaccharide; sulfated derivatives