title: Eugenol-loaded chitosan nanoparticles: I. Thermal stability improvement of eugenol through encapsulation.
abstract: The objective of the present work was to improve the thermal stability of eugenol by encapsulating into chitosan nanoparticles via an emulsion-ionic gelation crosslinking method. The influences of the initial eugenol content and tripolyphosphate (TPP) concentration on the loading capacity (LC), encapsulation efficiency (EE), morphology and surface charge of the eugenol-loaded chitosan nanoparticles were also investigated. LC and EE tended to increase with increasing initial eugenol content and decreasing TPP concentration. Particles with LC of 12% and EE of 20% exhibited a spherical shape with an average size of less than 100 nm. Thermal stability of the encapsulated eugenol was verified through its extrusion at 155°C with a model plastic, i.e. thermoplastic flour (TPF). TPF containing encapsulated eugenol showed 8-fold higher remaining eugenol content and 2.7-fold greater radical scavenging activity than that containing naked eugenol. The results suggest the possible use of eugenol-loaded chitosan nanoparticles as antioxidants in bioactive plastics for food packaging.
authors.affiliation: Department of Packaging and Materials Technology, Faculty of Agro-Industry, Kasetsart University, Bangkok 10900, Thailand.
authors.forename: Sarekha
authors.initials: S
authors.lastname: Woranuch
authors.forename: Rangrong
authors.initials: R
authors.lastname: Yoksan
mesh_terms: D048271:Chitosan / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry; D005054:Eugenol / Q000737:chemistry*; D005782:Gels / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry*; D013696:Temperature
chemical_list: D003432:Cross-Linking Reagents; D005782:Gels; D005054:Eugenol; D048271:Chitosan