title: Oxone-mediated oxidative cleavage of β-keto esters and 1,3-diketones to α-keto esters and 1,2-diketones in aqueous medium.
abstract: A versatile and highly efficient method for the direct synthesis of α-keto esters and 1,2-diketones has been developed. This approach utilizes the oxidative cleavage of a variety of β-keto esters and 1,3-diketones mediated by an Oxone/aluminum trichloride system. The simple one-step oxidation reaction proceeded selectively in aqueous media to afford products in high yields, short reaction times, and environmentally benign conditions.
authors.affiliation: Department of Chemistry, University of Crete, Heraklion 71003, Crete, Greece.
authors.forename: Anastasios
authors.initials: A
authors.lastname: Stergiou
authors.forename: Anna
authors.initials: A
authors.lastname: Bariotaki
authors.forename: Dimitris
authors.initials: D
authors.lastname: Kalaitzakis
authors.forename: Ioulia
authors.initials: I
authors.lastname: Smonou
mesh_terms: D004952:Esters / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013464:Sulfuric Acids / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D004952:Esters; D007659:Ketones; D013464:Sulfuric Acids; D014867:Water; C048813:potassium peroxymonosulfuric acid