title: Osteosarcoma of breast: a rare case of extraskeletal osteosarcoma.
abstract: Primary osteogenic sarcomas of the breast are exceptionally uncommon. We describe such a case occurring in a 50 year-old woman who presented with a large painful mass in her left breast. Simple mastectomy of the left breast was performed. Microscopical and immunohistochemical findings established the diagnosis of primary osteogenic sarcoma. Similar to extremity osteosarcoma, adjuvant adriamycin and cisplatin based chemotherapy and external beam radiotherapy was given to the present case. She remained well 57 months later, without tumor recurrence. The current article made a literature search proving the rarity of this lesion type and discusses in detail the diagnostic implications and the treatment of this rare site tumor entity.
authors.affiliation: Department of Surgical Oncology, Dr BRA-IRCH, New Delhi, India.
authors.forename: Ashwin A
authors.initials: AA
authors.lastname: Kallianpur
authors.forename: Rakesh
authors.initials: R
authors.lastname: Gupta
authors.forename: Dillip K
authors.initials: DK
authors.lastname: Muduly
authors.forename: Arvind
authors.initials: A
authors.lastname: Kapali
authors.forename: Kiran C
authors.initials: KC
authors.lastname: Subbarao
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D059186:Chemoradiotherapy, Adjuvant / Q000379:methods; D005260:Female; D006801:Humans; D015413:Mastectomy, Simple / Q000379:methods; D008875:Middle Aged; D012516:Osteosarcoma / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery