title: Spondyloarthritis associated with acne conglobata, hidradenitis suppurativa and dissecting cellulitis of the scalp: a review with illustrative cases.
abstract: To review and highlight the association of acne conglobata, hidradenitis suppurativa, and dissecting cellulitis of the scalp with inflammatory arthritic conditions, we report five illustrative patients with this association, and a review of the literature. All our patients were African-American males, and their skin disease present before the onset of arthritis. Both asymmetric peripheral arthritis and axial disease can occur. The arthritis is usually insidious and lacks association with rheumatoid factor and HLA-B27. Imaging of peripheral joints can reveal erosions, periosteal bone reaction and new bone formation. When the axial skeleton is involved, imaging can reveal sacroiliitis, syndesmophyte formation. NSAIDs, oral and intra-articular steroids, DMARDs and TNF alpha antagonists have all been used with success. Controlled trials with larger numbers of patients are needed to assess which treatment options are the most effective for this group of patients.
authors.affiliation: Division of Rheumatology, Case Western Reserve University School of Medicine, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH, 44109-1998, USA.
authors.forename: Debbie T
authors.initials: DT
authors.lastname: Lim
authors.forename: Neena M
authors.initials: NM
authors.lastname: James
authors.forename: Sobia
authors.initials: S
authors.lastname: Hassan
authors.forename: Muhammad A
authors.initials: MA
authors.lastname: Khan
mesh_terms: D000152:Acne Vulgaris / Q000150:complications*; D000328:Adult; D000368:Aged; D018501:Antirheumatic Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000150:complications*; D017497:Hidradenitis Suppurativa / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012536:Scalp Dermatoses / Q000150:complications*; D025241:Spondylarthritis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy
chemical_list: D018501:Antirheumatic Agents