title: From squalene to brassinolide: the steroid metabolic and signaling pathways across the plant kingdom.
abstract: The plant steroid hormones, brassinosteroids (BRs), and their precursors, phytosterols, play major roles in plant growth, development, and stress tolerance. Here, we review the impressive progress made during recent years in elucidating the components of the sterol and BR metabolic and signaling pathways, and in understanding their mechanism of action in both model plants and crops, such as Arabidopsis and rice. We also discuss emerging insights into the regulations of these pathways, their interactions with other hormonal pathways and multiple environmental signals, and the putative nature of sterols as signaling molecules.
authors.affiliation: CropDesign NV, a BASF Plant Science Company, 9052 Gent, Belgium.
authors.forename: Cécile
authors.initials: C
authors.lastname: Vriet
authors.forename: Eugenia
authors.initials: E
authors.lastname: Russinova
authors.forename: Christophe
authors.initials: C
authors.lastname: Reuzeau
mesh_terms: D001692:Biological Transport; D060406:Brassinosteroids / Q000378:metabolism*; D010840:Phytosterols / Q000096:biosynthesis / Q000378:metabolism; D010944:Plants / Q000378:metabolism*; D015398:Signal Transduction; D013185:Squalene / Q000378:metabolism*; D013260:Steroids, Heterocyclic / Q000378:metabolism*
chemical_list: D060406:Brassinosteroids; D010840:Phytosterols; D013260:Steroids, Heterocyclic; D013185:Squalene; C023623:brassinolide
keywords: Arabidopsis; brassinosteroids.; phytosterols; rice