title: Ciclohexadespipeptide beauvericin degradation by different strains of Saccharomyces cerevisiae.
abstract: The interaction between the mycotoxin beauvericin (BEA) and 9 yeast strains of Saccharomyces cerevisiae named LO9, YE-2, YE5, YE-6, YE-4, A34, A17, A42 and A08 was studied. The biological degradations were carried out under aerobic conditions in the liquid medium of Potato Dextrose Broth (PDB) at 25°C for 48 h and in a food/feed system composed of corn flour at 37°C for 3 days, respectively. BEA present in fermented medium and corn flour was determined using liquid chromatography coupled to the mass spectrometry detector in tandem (LC-MS/MS) and the BEA degradation products produced during the fermentations were determined using the technique of the liquid chromatography coupled to a linear ion trap (LIT). Results showed that the S. cerevisiae strains reduced meanly the concentration of the BEA present in PDB by 86.2% and in a food system by 71.1%. All the S. cerevisiae strains used in this study showed a significant BEA reduction during the fermentation process employed.
authors.affiliation: Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Burjassot, Spain. giuseppe.meca@uv.es
authors.forename: G
authors.initials: G
authors.lastname: Meca
authors.forename: T
authors.initials: T
authors.lastname: Zhou
authors.forename: X Z
authors.initials: XZ
authors.lastname: Li
authors.forename: A
authors.initials: A
authors.lastname: Ritieni
authors.forename: J
authors.initials: J
authors.lastname: Mañes
mesh_terms: D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D047630:Depsipeptides / Q000032:analysis / Q000737:chemistry / Q000378:metabolism*; D055664:Electrochemical Techniques; D005285:Fermentation; D005506:Food Contamination / Q000517:prevention & control*; D005511:Food Handling; D006868:Hydrolysis; D015394:Molecular Structure; D009183:Mycotoxins / Q000031:analogs & derivatives / Q000032:analysis / Q000737:chemistry / Q000378:metabolism*; D035281:Plant Tubers / Q000737:chemistry; D019936:Probiotics / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000254:growth & development / Q000378:metabolism*; D012639:Seeds / Q000737:chemistry; D011198:Solanum tuberosum / Q000737:chemistry; D013045:Species Specificity; D021241:Spectrometry, Mass, Electrospray Ionization; D013213:Starch / Q000378:metabolism; D053719:Tandem Mass Spectrometry; D003313:Zea mays / Q000737:chemistry
chemical_list: D047630:Depsipeptides; D009183:Mycotoxins; C004456:beauvericin; D013213:Starch
keywords: Beauvericin; Detoxification; Fusarium spp.; LC–MS/MS; Probiotics