title: Staphylococcus aureus osteomyelitis: bad to the bone.
abstract: Osteomyelitis is a debilitating bone infection often caused by the bacterial pathogen Staphylococcus aureus. In this issue, Cassat et al. (2013) develop a high-resolution microcomputed tomography (microCT) method to visualize bone remodeling during S. aureus infection and discover that the metalloprotease aureolysin plays a critical role in modulating osteomyelitis pathogenesis.
authors.affiliation: Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Olson
authors.forename: Alexander R
authors.initials: AR
authors.lastname: Horswill
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism*; D016723:Bone Remodeling; D008666:Metalloendopeptidases / Q000378:metabolism*; D010019:Osteomyelitis / Q000473:pathology*; D013203:Staphylococcal Infections / Q000473:pathology*; D013211:Staphylococcus aureus / Q000472:pathogenicity*; D037521:Virulence Factors / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D037521:Virulence Factors; D008666:Metalloendopeptidases; C115504:aureolysin