title: Antiproliferative activity, cell cycle, and apoptosis studies of a series of 6-substituted 9H-purin-9-yl-pyridinium derivatives on a human cervical carcinoma cell line.
authors.affiliation: Departamento de Química Farmacéutica y Orgánica, Facultad de Farmacia, Universidad de Granada, Campus de Cartuja, 18071 Granada, Spain.
authors.forename: Belén
authors.initials: B
authors.lastname: Rubio-Ruiz
authors.forename: Javier
authors.initials: J
authors.lastname: Ramos-Torrecillas
authors.forename: Fermín
authors.initials: F
authors.lastname: Capitán-Cañadas
authors.forename: Rosario
authors.initials: R
authors.lastname: Sánchez-Martín
authors.forename: Miguel Ángel
authors.initials: MÁ
authors.lastname: Gallo
authors.forename: Antonio
authors.initials: A
authors.lastname: Espinosa
authors.forename: Concepción
authors.initials: C
authors.lastname: Ruiz
authors.forename: Ana
authors.initials: A
authors.lastname: Conejo-García
authors.forename: Antonio
authors.initials: A
authors.lastname: Entrena
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity*; D017209:Apoptosis / Q000187:drug effects*; D053148:Caspase 3 / Q000378:metabolism; D059447:Cell Cycle Checkpoints / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D005260:Female; D006367:HeLa Cells; D006801:Humans; D011726:Pyridinium Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D013329:Structure-Activity Relationship; D002583:Uterine Cervical Neoplasms / Q000378:metabolism / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D011726:Pyridinium Compounds; D053148:Caspase 3
keywords: antiproliferative activity; apoptosis; caspase-3; cell cycle; pyridinium compounds