title: Affective temperaments and psychotropic adherence.
abstract: BACKGROUND
  It is generally accepted that a range of factors affect adherence to psychotropic medications. In the present study, we focused on the influence of affective temperaments (i.e., depressive, hyperthymic, cyclothymic, irritable, and anxious temperaments) on treatment adherence.
  
  
  METHODS
  Thirty-eight psychiatric consecutive inpatients were instructed to perform Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-Autoquestionnaire version (TEMPS-A) for affective temperaments, Drug attitude inventory-10 (DAI-10) for concordance and persistence, and Visual Analogue Scale (VAS) for compliance.
  
  
  RESULTS
  VAS scores for dose compliance were significantly and negatively associated with irritable temperament scores whereas DAI-10 scores were significantly and positively associated with male gender, depressive temperament scores and hyperthymic temperament scores.
  
  
  CONCLUSIONS
  The main limitations of the study were the relatively small number of subjects and the lack of objective method of adherence.
  
  
  CONCLUSIONS
  These findings suggest that patients with irritable temperament may be poor in their compliance with treatment, and that more education may be required for patients with irritable temperament in order to maintain good compliance. In contrast, men and patients with depressive or hyperthymic temperament have a relatively positive attitude towards medication.
authors.affiliation: Department of Neuropsychiatry, Oita University, Faculty of Medicine, Idaigaoka 1-1, Hasama-machi, Yufu-city, Oita 879-5593, Japan.
authors.forename: Kimie
authors.initials: K
authors.lastname: Kamei
authors.forename: Takeshi
authors.initials: T
authors.lastname: Terao
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Katayama
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Hoaki
mesh_terms: D000328:Adult; D000339:Affect; D001007:Anxiety / Q000523:psychology; D005260:Female; D006801:Humans; D007508:Irritable Mood; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D001523:Mental Disorders / Q000188:drug therapy* / Q000523:psychology*; D008875:Middle Aged; D010555:Personality Inventory / Q000706:statistics & numerical data; D011619:Psychotropic Drugs / Q000008:administration & dosage*; D011795:Surveys and Questionnaires; D013694:Temperament
chemical_list: D011619:Psychotropic Drugs
keywords: Adherence; DAI-10; Temperament; VAS