title: The management of orthostatic hypotension in Parkinson's disease.
abstract: Orthostatic hypotension (OH) is a common and disabling symptom affecting Parkinson's disease (PD) patients. We present the effect of the different therapies commonly used to manage PD on this clinical manifestation. For this purpose, we describe the relationship between OH and the current treatments employed in PD, such as L-DOPA, dopaminergic agonists, and continuous dopaminergic stimulation therapies. Additionally, we review the therapeutic measures that could be used to ameliorate OH. There are different approaches to deal with this manifestation, including pharmacological and non-pharmacological treatments, although none of them is specifically aimed for treating OH in PD.
authors.affiliation: Department of Neurology, University Hospital "12 de Octubre," Madrid , Spain ; Department of Medicine, Faculty of Medicine, Complutense University , Madrid , Spain ; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas , Madrid , Spain ; Instituto de Salud Carlos III , Madrid , Spain.
authors.forename: Alvaro
authors.initials: A
authors.lastname: Sánchez-Ferro
authors.forename: Julián
authors.initials: J
authors.lastname: Benito-León
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Gómez-Esteban
keywords: L-DOPA; Parkinson’s disease; continuous dopaminergic stimulation; dopamine agonists; orthostatic hypotension; treatment