title: Direct 2-acetoxylation of quinoline N-oxides via copper catalyzed C-H bond activation.
abstract: An efficient and direct 2-acetoxylation of quinoline N-oxides via copper(I) catalyzed C-H bond activation has been developed. This transformation was achieved using TBHP as an oxidant in the cross-dehydrogenative coupling (CDC) reaction of quinoline N-oxides with aldehydes, and provided a practical pathway to 2-acyloxyl quinolines.
authors.affiliation: Department of Chemistry, Henan Key Laboratory of Chemical Biology and Organic Chemistry, Zhengzhou University, Zhengzhou, 450052, PR China.
authors.forename: Xuan
authors.initials: X
authors.lastname: Chen
authors.forename: Chongwei
authors.initials: C
authors.lastname: Zhu
authors.forename: Xiuling
authors.initials: X
authors.lastname: Cui
authors.forename: Yangjie
authors.initials: Y
authors.lastname: Wu
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure; D010087:Oxides / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000447:Aldehydes; D010087:Oxides; D011804:Quinolines; D003300:Copper