title: Trifocal distraction osteogenesis for reconstruction of skull defect.
abstract: OBJECTIVE
  To apply trifocal distraction osteogenesis in canine model of skull segmental defects and to provide reference for clinical treatment.
  
  
  METHODS
  Six labrador dogs were selected in this study and divided into observation group and control group randomly. Each group contained 3 dogs. Skull segmental defects models were established by surgery, and dogs in bservation group received trifocal distraction osteogenesis treatment. Bone density was observed and compared between two groups during treatment.
  
  
  RESULTS
  There were no significant difference in bone density between two groups on th 1st day (P>0.05). The bone density of observation group on the 30th day, and 60th day were higher than that of control group (P<0.01).
  
  
  CONCLUSIONS
  Trifocal distraction osteogenesis has significant clinical effect, and it would be widely used in clinical treatment.
authors.affiliation: Department of Plastic Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Ke
authors.forename: Hai-Song
authors.initials: HS
authors.lastname: Xu
authors.forename: Zhi-Hong
authors.initials: ZH
authors.lastname: Fan
mesh_terms: D000818:Animals; D001847:Bone Diseases / Q000628:therapy*; D004195:Disease Models, Animal; D004285:Dogs; D019857:Osteogenesis, Distraction / Q000379:methods*; D012886:Skull / Q000293:injuries*; D016896:Treatment Outcome