title: Patient satisfaction with psychotropic drugs: Validation of the PAtient SAtisfaction with Psychotropic (PASAP) scale in patients with bipolar disorder.
abstract: OBJECTIVE
  The PAtient SAtisfaction with Psychotropic (PASAP) scale is a self-completed questionnaire measuring satisfaction with psychotropic medication. The aim of the study was to describe its development in French and its psychometric properties.
  
  
  METHODS
  Scale construction was based on an extensive search of the literature. The item reduction process required semi-structured interviews of psychiatric outpatients (n=30). The final version of the PASAP is a 9-item, 5-point Likert-type scale, covering the scope of effectiveness and adherence. To assess the psychometric properties of the scale, French patients with an acute manic episode (n=314) from a large European observational cohort completed the PASAP scale 3 months after psychotropic treatment initiation/change. Internal validity and reliability were assessed using principal component analysis (PCA). Concurrent validity was assessed using comparisons to physician-rated satisfaction with life, illness severity, mood relapse, compliance and side effects.
  
  
  RESULTS
  Participation rate was 68.4%. PCA was in favour of uni-dimensionality. Cronbach's α coefficient was 0.85 (95%CI 0.83-0.88). All five concurrent measures were significantly associated with the PASAP score.
  
  
  CONCLUSIONS
  The PASAP scale showed good psychometric properties in a large bipolar population and thus seems adequate for evaluating treatment satisfaction. Its short length and good acceptability makes it suitable for clinical research.
authors.affiliation: INSERM 669, Paris-Sud University and Paris-Descartes University, Maison des Adolescents, 97, boulevard de Port-Royal, 75014 Paris, France. Electronic address: nordon.clementine@gmail.com.
authors.forename: C
authors.initials: C
authors.lastname: Nordon
authors.affiliation: INSERM 669, Paris-Sud University and Paris-Descartes University, Maison des Adolescents, 97, boulevard de Port-Royal, 75014 Paris, France.
authors.forename: B
authors.initials: B
authors.lastname: Falissard
authors.affiliation: PRA Structure - Économie de la Santé, Lilly France, 17, rue Pagès, 92150 Suresnes, France.
authors.forename: S
authors.initials: S
authors.lastname: Gerard
authors.affiliation: Zurich University Psychiatric Hospital, Lenggstr. 31, Mail Box 68, CH-8029 Zurich, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Angst
authors.affiliation: Service de psychiatrie adulte, Sainte-Marguerite University Hospital Centre, 270, boulevard de Sainte-Marguerite, 13009 Marseille, France.
authors.forename: J M
authors.initials: JM
authors.lastname: Azorin
authors.affiliation: INSERM 669, Paris-Sud University and Paris-Descartes University, Maison des Adolescents, 97, boulevard de Port-Royal, 75014 Paris, France; Département de Psychiatrie et d'Addictologie, Paul Brousse Hospital, 12, avenue Paul-Vaillant-Couturier, 94804 Villejuif cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Luquiens
authors.affiliation: Lilly Research Centre, Eli Lilly and Company Limited, Erl Wood Manor, Sunninghill road, Windlesham, Surrey, GU20 6PH, United Kingdom.
authors.forename: C
authors.initials: C
authors.lastname: Reed
authors.affiliation: INSERM 669, Paris-Sud University and Paris-Descartes University, Maison des Adolescents, 97, boulevard de Port-Royal, 75014 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Lukasiewicz
authors.affiliation: INSERM 669, Paris-Sud University and Paris-Descartes University, Maison des Adolescents, 97, boulevard de Port-Royal, 75014 Paris, France; Direction de la Politique Médicale, Assistance Publique-Hôpitaux de Paris, 3, avenue Victoria, 75004 Paris, France.
authors.forename: I
authors.initials: I
authors.lastname: Gasquet
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011594:Psychometrics / Q000295:instrumentation; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires / Q000592:standards*
chemical_list: D011619:Psychotropic Drugs
keywords: Patient satisfaction; Patient-reported outcomes; Psychometry and assessments in psychiatry; Psychotropic drugs; Validation study