title: [Non-invasive diagnosis of prostate cancer: serum and urine markers].
abstract: The great number of biomarkers basic research is presenting in different clinical scenarios of prostate cancer demands the scientific community rigor in their molecular and clinical development for the selection of those which could supply diagnostic and prognostic information for the established nomograms of clinical-pathological factors. Prostate cancer, due to its prevalence and heterogeneity, needs a more directed diagnosis, characterization of malignant potential and monitoring of its multiple therapies. In this review article we try to go over the recent incorporation of new serum and urine markers in the clinical management of this tumor, emphasizing those with greater clinical development.
authors.affiliation: Instituto Valenciano de Oncología, Valencia, España. jrubio@fivo.org
authors.forename: J
authors.initials: J
authors.lastname: Rubio-Briones
authors.forename: I
authors.initials: I
authors.lastname: Casanova-Casas
authors.forename: A
authors.initials: A
authors.lastname: Fernández-Serra
authors.forename: J
authors.initials: J
authors.lastname: Casanova Ramón-Borja
authors.forename: M
authors.initials: M
authors.lastname: Ramírez Backhaus
authors.forename: A
authors.initials: A
authors.lastname: Collado Sierra
authors.forename: J
authors.initials: J
authors.lastname: Domínguez-Escrig
authors.forename: A
authors.initials: A
authors.lastname: Gómez-Ferrer
authors.forename: J A
authors.initials: JA
authors.lastname: López-Guerrero
mesh_terms: D000818:Animals; D000951:Antigens, Neoplasm / Q000235:genetics; D000970:Antineoplastic Agents / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood* / Q000652:urine*; D001706:Biopsy; D006728:Hormones / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008967:Molecular Biology; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D011379:Prognosis; D017430:Prostate-Specific Antigen / Q000032:analysis / Q000235:genetics; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000378:metabolism* / Q000532:radiotherapy / Q000652:urine
chemical_list: D000951:Antigens, Neoplasm; D000970:Antineoplastic Agents; D015415:Biomarkers; D006728:Hormones; C479341:prostate cancer antigen 3, human; D017430:Prostate-Specific Antigen