title: Comparison of clinical and laboratory characteristics of intestinal amebiasis with shigellosis among patients visiting a large urban diarrheal disease hospital in Bangladesh.
abstract: Between 1993 and 2011, a total of 371 intestinal amebiasis (IA), caused by Entamoeba histolytica cases were compared with 1,113 shigellosis (randomly selected) patients of icddr,b, excluding co-infections (rotavirus and Vibrio cholerae) in two age stratums: 0-14 years of age and ≥ 15 years of age. The number of IA and shigellosis cases gradually reduced over the study period. In multivariate analysis, individuals 0-14 years of age, slum dwellers (odds ratio [OR] 3.51; 95% confidence interval [CI] 1.69-7.24; P < 0.001), red blood cell (0.44 [0.24-0.86] 0.016), fecal leukocytes (0.17 [0.07-0.33] < 0.001), and alkaline stool (0.16 [0.07-0.36] < 0.001) were independently associated with IA; and among individuals ≥ 15 years of age, living in the slum area (1.88 [1.12-3.14] 0.016), watery stool (2.21 [1.37-3.55] 0.001), use of antimicrobials before visiting hospital (0.67 [0.46-0.99] 0.047), red blood cell (0.45 [0.22-0.94] 0.036), and fecal leukocytes (0.21 [0.12-0.35] < 0.001) in stool were independently associated with IA. Socio-demographic and clinical characteristics of IA and shigellosis varied distantly from each other.
authors.affiliation: International Centre for Diarrheal Disease Research, Bangladesh (icddr,b).
authors.forename: Sumon Kumar
authors.initials: SK
authors.lastname: Das
authors.forename: Mohammod Jobayer
authors.initials: MJ
authors.lastname: Chisti
authors.forename: Mohammad Abdul
authors.initials: MA
authors.lastname: Malek
authors.forename: Mohammed Abdus
authors.initials: MA
authors.lastname: Salam
authors.forename: Tahmeed
authors.initials: T
authors.lastname: Ahmed
authors.forename: Abu Syed Golam
authors.initials: AS
authors.lastname: Faruque
authors.forename: Dinesh
authors.initials: D
authors.lastname: Mondal
mesh_terms: D000293:Adolescent; D000562:Amebiasis / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology*; D001459:Bangladesh / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology / Q000382:microbiology / Q000469:parasitology / Q000473:pathology*; D004405:Dysentery, Bacillary / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016017:Odds Ratio; D011203:Poverty; D012307:Risk Factors; D014505:Urban Population