title: Concentrated platelet-rich plasma used in root canal revascularization: 2 case reports.
abstract: OBJECTIVE
  To present two case reports describing the treatment of immature teeth with necrotic pulps using concentrated platelet-rich plasma (cPRP) with 12-month clinical and radiographic follow-up.
  
  
  CONCLUSIONS
  Root canal revascularization was performed on immature permanent teeth clinically and radiographically diagnosed as requiring root canal treatment. Following disinfection of the canal space with triple antibiotic paste (1 : 1 : 1: ciprofloxacin, metronidazole and cefaclor), a tissue scaffold was created with cPRP prepared using 2-step centrifugation. The final restoration was completed with white mineral trioxide aggregate and composite resin. The patients were recalled for clinical and radiographic evaluations every 3 months. At the 12-month follow-up apical closure by narrowing of the apical foramen and convergence of the apical walls in the treated teeth was observed.
authors.affiliation: Department of Pedodontics, Faculty of Dentistry, Ankara University, Ankara, Turkey.
authors.forename: T
authors.initials: T
authors.lastname: Bezgin
authors.forename: A D
authors.initials: AD
authors.lastname: Yilmaz
authors.forename: B N
authors.initials: BN
authors.lastname: Celik
authors.forename: H
authors.initials: H
authors.lastname: Sönmez
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002433:Cefaclor / Q000008:administration & dosage; D002648:Child; D002939:Ciprofloxacin / Q000008:administration & dosage; D003786:Dental Pulp Cavity / Q000098:blood supply*; D004203:Disinfection; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage; D018919:Neovascularization, Physiologic; D053657:Platelet-Rich Plasma
chemical_list: D000900:Anti-Bacterial Agents; D008795:Metronidazole; D002939:Ciprofloxacin; D002433:Cefaclor
keywords: concentrated platelet-rich plasma; immature teeth; revascularization