title: Paraneoplastic cerebellar degeneration associated with squamous cell carcinoma of the lung.
abstract: We report a 78-year-old man who presented with rapidly progressive cerebellar ataxia, dysarthria and vertigo. MRI of the brain showed no evidence of infiltrative pathology in the posterior fossa. Cerebrospinal fluid analysis revealed an elevated protein and pleocytosis. He was subsequently diagnosed with squamous cell carcinoma of the lung on bronchoscopy. Paraneoplastic cerebellar degeneration (PCD) was diagnosed. To our knowledge, there are only two previously reported patients with PCD associated with squamous cell carcinoma of the lung.
authors.affiliation: Department of Neurology, Royal Melbourne Hospital, Grattan Street, Parkville, Melbourne, VIC 3052, Australia. Electronic address: Jessica.Day@mh.org.au.
authors.forename: Jessica
authors.initials: J
authors.lastname: Day
authors.forename: Bernard
authors.initials: B
authors.lastname: Yan
authors.forename: Richard De
authors.initials: RD
authors.lastname: Boer
authors.forename: Alpha
authors.initials: A
authors.lastname: Tsui
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008198:Lymph Nodes / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D020362:Paraneoplastic Cerebellar Degeneration / Q000150:complications* / Q000175:diagnosis
keywords: Cerebellar ataxia; Paraneoplastic; Squamous cell carcinoma