title: A dual-functional electrochemical biosensor for the detection of prostate specific antigen and telomerase activity.
abstract: A new dual-functional electrochemical biosensor for the detection of prostate specific antigen (PSA) and telomerase activity was successfully developed based on a sandwich immunobinding format and telomerization assisted hemin-G-quadruplex-based DNAzyme as a biolabel.
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.forename: Cai-Yu
authors.initials: CY
authors.lastname: Lu
authors.forename: Hong
authors.initials: H
authors.lastname: Zhou
authors.forename: Jing-Juan
authors.initials: JJ
authors.lastname: Xu
authors.forename: Zong-Hua
authors.initials: ZH
authors.lastname: Wang
authors.forename: Hong-Yuan
authors.initials: HY
authors.lastname: Chen
mesh_terms: D015374:Biosensing Techniques; D055664:Electrochemical Techniques; D006801:Humans; D007610:Kallikreins / Q000032:analysis* / Q000378:metabolism; D017430:Prostate-Specific Antigen / Q000032:analysis* / Q000378:metabolism; D019098:Telomerase / Q000737:chemistry / Q000378:metabolism*
chemical_list: D019098:Telomerase; C549870:KLK3 protein, human; D007610:Kallikreins; D017430:Prostate-Specific Antigen