title: Rubber jaw in a Weimaraner dog due to juvenile nephropathy. A case without evidence for genetic involvement.
abstract: The case of a 5-month-old male Weimaraner dog with severe osteodystrophia fibrosa (rubber jaw) and renal insufficiency is presented. Kidneys were smaller than normal with a granular cortical surface and a histopathological end-stage diagnosis consistent with juvenile nephropathy. Analysis of four described genetic mutations associated with Alport syndrome in dogs revealed no evidence for familiar inheritance in this dog.
authors.affiliation: Institut für Veterinär-Pathologie, der Justus-Liebeig-Universität Gießen, Frankfurter Straße 96, 35392 Gießen. laura.brachthaeuser@vetmed.uni-giessen.de
authors.forename: L
authors.initials: L
authors.lastname: Brachthäuser
authors.forename: C-H
authors.initials: CH
authors.lastname: Pingen
authors.forename: W
authors.initials: W
authors.lastname: Hecht
authors.forename: M
authors.initials: M
authors.lastname: Reinacher
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D007571:Jaw Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D051437:Renal Insufficiency / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*