title: [Assessment of persistent potential dominant pathogens of acute intestinal infections].
abstract: To determine the prevalence,and etiological structure of acute intestinal infections, to investigate the dominant agents' persistence factors. According with materials of statistical reports we did the retrospective epidemiological analysis of acute intestinal infections incidence in Sumy region from 2006 till 2011. Biological properties of 40 strains of Klebsiella pneumonia, 40 strains of Enterobacter cloacae and 50 strains of Staphylococcus aureus were investigated. Moderate trend of acute intestinal infections incidence increase was indicated. Bacteria of genera Klebsiella, Enterobacter, Staphylococcus were predominated in etiological structure. Incidence of acute diarrheal infections caused by Klebsiella and Enterobacter was reached the maximum in the spring-summer period. The incidence of staphylococcal etiology was discrete. The strains of Klebsiella pneumonia, Staphylococcus aureus and Enterobacter cloacae were remarkable for different frequency and intensity of persistence factors. Аnti-interferon activity was detected in 100% of clinical isolates of microorganisms, anti-lysozym activity was detected in 87.3 ± 2.9% of clinical isolates of microorganisms, anti-complementary activity was detected in 72.3 ± 3.9% of clinical isolates of microorganisms. Biological properties of opportunistic pathogens that cause acute intestinal infections can be used as epidemiological factors for differentiation of microorganisms pathogenicity.
authors.forename: N G
authors.initials: NG
authors.lastname: Malysh
authors.forename: V N
authors.initials: VN
authors.lastname: Golubnichaia
authors.forename: N D
authors.initials: ND
authors.lastname: Chemich
authors.forename: S I
authors.initials: SI
authors.lastname: Doan
mesh_terms: D000208:Acute Disease; D016972:Enterobacter cloacae / Q000302:isolation & purification / Q000472:pathogenicity; D004756:Enterobacteriaceae Infections / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D007410:Intestinal Diseases / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D007710:Klebsiella Infections / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D007711:Klebsiella pneumoniae / Q000302:isolation & purification / Q000472:pathogenicity; D012189:Retrospective Studies; D012621:Seasons; D013211:Staphylococcus aureus / Q000302:isolation & purification / Q000472:pathogenicity