title: Current trends in the empirical study of cognitive remediation for schizophrenia.
abstract: Cognitive remediation (CR) for schizophrenia is a learning-based behavioural skills training intervention designed to enhance neuro and (or) social cognitive skills, with the ultimate goal of generalization to improve psychosocial outcomes. This review summarizes conceptual approaches to CR for schizophrenia and the evidence for efficacy in clinical research settings. Four issues are at the forefront of ongoing research: the identification of techniques that produce the largest cognitive change, delineation of techniques that enhance transfer of cognitive skills to functional skills, the identification of CR methods that can be personalized to meet the specific cognitive and functional needs of each individual, and, all the while, ensuring that when CR methods are developed in a research setting, they remain scalable for delivery in the larger clinical community. In response to these issues, 3 prominent research trends have emerged: the rise of a new generation of computerized restorative cognitive training, the integration of CR with skills training to promote generalization, and the application of techniques to enhance motivation and learning during CR. As data on the neural basis of learning in people with schizophrenia become available, new technologies that harness the ability of the brain to make sustainable, functional changes may be integrated within a therapeutic context that promotes a personalized approach to learning. The development of transportable and scalable methods of CR that maximize the ability of people with schizophrenia to improve cognition will help them achieve personal goals for recovery.
authors.affiliation: Department of Psychiatry, Columbia University Medical Center, New York, NY, USA.
authors.forename: Alice M
authors.initials: AM
authors.lastname: Saperstein
authors.forename: Matthew M
authors.initials: MM
authors.lastname: Kurtz
mesh_terms: D035843:Biomedical Research / Q000639:trends; D001921:Brain / Q000503:physiopathology; D002170:Canada; D003072:Cognition Disorders / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology / Q000534:rehabilitation*; D015928:Cognitive Behavioral Therapy / Q000379:methods / Q000639:trends*; D003131:Combined Modality Therapy; D003194:Computer-Assisted Instruction / Q000639:trends; D056348:Emotional Intelligence; D005544:Forecasting; D005793:Generalization, Psychological; D006801:Humans; D009042:Motivation; D009473:Neuronal Plasticity / Q000502:physiology; D009483:Neuropsychological Tests; D057285:Precision Medicine / Q000639:trends; D016032:Randomized Controlled Trials as Topic; D012559:Schizophrenia / Q000175:diagnosis / Q000503:physiopathology / Q000534:rehabilitation*; D012565:Schizophrenic Psychology
keywords: cognitive remediation; neurocognition; neuroplasticity; psychiatric rehabilitation; schizophrenia