title: Direct synthesis of pyridines and quinolines by coupling of γ-amino-alcohols with secondary alcohols liberating H2 catalyzed by ruthenium pincer complexes.
abstract: A novel, one-step synthesis of substituted pyridine- and quinoline-derivatives was achieved by acceptorless dehydrogenative coupling of γ-aminoalcohols with secondary alcohols. The reaction involves consecutive C-N and C-C bond formation, catalyzed by a bipyridyl-based ruthenium pincer complex with a base.
authors.affiliation: Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot 76100, Israel.
authors.forename: Dipankar
authors.initials: D
authors.lastname: Srimani
authors.forename: Yehoshoa
authors.initials: Y
authors.lastname: Ben-David
authors.forename: David
authors.initials: D
authors.lastname: Milstein
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D000438:Alcohols; D009942:Organometallic Compounds; D011725:Pyridines; D011804:Quinolines; D012428:Ruthenium; D006859:Hydrogen