title: Association between melanocytic neoplasms and seborrheic keratosis: more than a coincidental collision?
abstract: Clinical observations and an expanding knowledge of cell-to-cell communication have led us to speculate that the finding of a melanocytic nevus in conjunction with a seborrheic keratosis is more than a coincidental collision of two lesions. Here we present five cases demonstrating dermoscopic features of both melanocytic lesions and seborrheic keratoses with corresponding histology. Four cases demonstrate dermoscopic features of a melanocytic nevus and seborrheic keratosis, and the final case a melanoma arising in association with a seborrheic keratosis.
authors.affiliation: Dermatology Service, Memorial Sloan-Kettering Cancer Center, Hauppauge, NY, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Defazio
authors.forename: Iris
authors.initials: I
authors.lastname: Zalaudek
authors.forename: Klaus J
authors.initials: KJ
authors.lastname: Busam
authors.forename: Carlo
authors.initials: C
authors.lastname: Cota
authors.forename: Ashfaq
authors.initials: A
authors.lastname: Marghoob
keywords: cell-signalling; keratinocytes; melanocytes; melanocytic nevus; seborrheic keratosis