title: Deep brain stimulation improves quality of life in pantothenate kinase-associated neurodegeneration.
abstract: Pantothenate kinase-associated neurodegeneration (PKAN) is an uncommon extrapyramidal movement disorder characterized by the progressive incapacitating dystonia. Medical management is often incapable of reversing the dystonic symptoms. In recent years, stereotactic procedure like deep brain stimulation has been found effective in resolving the disabling dystonia and improving the quality of life. There are few cases in the world literature highlighting the usefulness of this technique. We report a case of 10-year-old girl who underwent bilateral Globus pallidus internus stimulation for PKAN.
authors.affiliation: Department of Pediatrics, Jaslok Hospital and Research Centre, Mumbai, India.
authors.forename: Kiran P
authors.initials: KP
authors.lastname: Sathe
authors.forename: Anaita U
authors.initials: AU
authors.lastname: Hegde
authors.forename: Paresh K
authors.initials: PK
authors.lastname: Doshi
keywords: Children; globus pallidus internus-deep brain stimulation; neurodegeneration with the brain iron accumulation; pantothenate kinase-associated neurodegeneration; secondary dystonia