title: [Rapid regression of infantile haemangioma with 2% propranolol ointment].
abstract: BACKGROUND
  Oral propranolol produces dramatic results in severe infantile haemangioma. We report a case of rapid and significant regression of an infantile haemangioma in infant treated topically with 2% propranolol ointment.
  
  
  METHODS
  A female infant aged 11 weeks was seen as an outpatient for two infantile haemangiomas on the front of the left knee and the vulva. After parental consent was given, the child was treated with a topical preparation of 2% propranolol ointment prepared by the pharmacy. Regression was rapid and on the 45th day, lesion size had been reduced by an estimated 75%. No adverse effects were observed.
  
  
  CONCLUSIONS
  Topical propranolol appears to be effective and safe for the treatment of superficial haemangiomas. Clinical trials are required to determine the optimal dosage and pharmaceutical form, method of use and treatment duration.
authors.affiliation: Service de dermatologie, CHU, Kara, Togo. ambatoure@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Mouhari-Toure
authors.forename: K-D
authors.initials: KD
authors.lastname: Azoumah
authors.forename: K
authors.initials: K
authors.lastname: Tchamdja
authors.forename: B
authors.initials: B
authors.lastname: Saka
authors.forename: K
authors.initials: K
authors.lastname: Kombaté
authors.forename: K
authors.initials: K
authors.lastname: Tchangaï-Walla
authors.forename: P
authors.initials: P
authors.lastname: Pitche
mesh_terms: D001786:Blood Glucose / Q000032:analysis; D004200:Diseases in Twins; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D018324:Hemangioma, Capillary / Q000151:congenital / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007717:Knee; D011433:Propranolol / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D012869:Skin Absorption; D012878:Skin Neoplasms / Q000151:congenital / Q000188:drug therapy*; D014429:Twins, Dizygotic; D014662:Vasoconstrictor Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D014846:Vulvar Neoplasms / Q000151:congenital / Q000188:drug therapy
chemical_list: D001786:Blood Glucose; D014662:Vasoconstrictor Agents; D011433:Propranolol