title: Postnatal outcome of congenital anomalies in low resource setting.
abstract: OBJECTIVE
  This study aimed to determine the postnatal outcome of congenital malformations in a tertiary care hospital of India.
  
  
  METHODS
  This was a prospective study of all women with prenatally detected major congenital malformations. Postnatal follow-up of live born babies was carried out for 1 year.
  
  
  RESULTS
  There were 574 cases with major congenital anomalies, 523 of which were fully followed. Only 69 women (13.6%) had the initial scan before 20 weeks of gestation. Craniospinal defects were the most common (42.7%), followed by genitourinary anomalies (28%). There was no live birth in cases such as anencephaly, iniencephaly, bilateral renal agenesis, gastroschisis, and cystic hygroma. Survival at 1 year was less than 25% in spina bifida, bilateral cystic kidneys, complex cardiac disease, and non-immune hydrops fetalis. In cases with mild hydrocephalus or unilateral and mild renal disease, the survival was over 75%.
  
  
  CONCLUSIONS
  In India, the majority of congenital anomalies present late in gestation. Although fetal outcome is invariably poor for severe defects, existing legislation in the country leaves pregnancy continuation as the only option.
authors.affiliation: Department of Obstetrics & Gynaecology, Lady Hardinge Medical College, New Delhi, India.
authors.forename: Manisha
authors.initials: M
authors.lastname: Kumar
authors.forename: Sumedha
authors.initials: S
authors.lastname: Sharma
authors.forename: Manisha
authors.initials: M
authors.lastname: Bhagat
authors.forename: Usha
authors.initials: U
authors.lastname: Gupta
authors.forename: Rama
authors.initials: R
authors.lastname: Anand
authors.forename: Archana
authors.initials: A
authors.lastname: Puri
authors.forename: Anuradha
authors.initials: A
authors.lastname: Singh
authors.forename: Abha
authors.initials: A
authors.lastname: Singh
mesh_terms: D000293:Adolescent; D000328:Adult; D000013:Congenital Abnormalities / Q000191:economics / Q000453:epidemiology*; D003266:Continuity of Patient Care / Q000191:economics / Q000706:statistics & numerical data; D005260:Female; D006295:Health Resources / Q000600:supply & distribution*; D006801:Humans; D007194:India / Q000453:epidemiology; D007231:Infant, Newborn; D011203:Poverty / Q000706:statistics & numerical data*; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000191:economics / Q000453:epidemiology*; D012017:Referral and Consultation / Q000191:economics / Q000706:statistics & numerical data; D055815:Young Adult