title: Stent-graft implantation for clinically diagnosed syphilitic aortic aneurysm in an HIV-infected patient.
abstract: We describe our experience with stent-graft placement in a patient with a clinically diagnosed syphilitic aortic aneurysm.The patient was a 43-year-old man with syphilitic and human immunodeficiency virus (HIV) co-infection. Computed tomography (CT) revealed an aortic aneurysm with 89 mm in maximum size which was located at distal aortic arch and was considered syphilis derived saccular aneurysm. The aneurysm was judged at high risk of rupture from its shape. We decided to perform stent-graft implantation. Before surgery, the patient was given antibacterial and anti-HIV agents. Hand-made fenestrated stent graft by Tokyo Medical University was implanted. The graft was placed from the ascending aorta to Th 9 level in the descending aorta. The aneurysm completely disappeared during follow-up, with no flare-up of syphilitic infection up to 2 years after surgery.The number of patients with syphilis and human immunodeficiency virus co-infection is now increasing. Stent-graft implantation may be an effective treatment in such immunocompromised patients.
authors.affiliation: Cardiovascular Center, Yokohama City University Medical Center, Yokohama, Kanagawa, Japan.
authors.forename: Shota
authors.initials: S
authors.lastname: Yasuda
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Imoto
authors.forename: Keiji
authors.initials: K
authors.lastname: Uchida
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kawaguchi
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Yokoi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shigematsu
authors.forename: Munetaka
authors.initials: M
authors.lastname: Masuda
mesh_terms: D000328:Adult; D000785:Aneurysm, Infected / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology / Q000601:surgery*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019380:Anti-HIV Agents / Q000627:therapeutic use; D001014:Aortic Aneurysm / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology / Q000601:surgery*; D001027:Aortography / Q000379:methods; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation; D060085:Coinfection; D057510:Endovascular Procedures / Q000009:adverse effects / Q000295:instrumentation; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D011474:Prosthesis Design; D015607:Stents; D013589:Syphilis, Cardiovascular / Q000150:complications / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology / Q000601:surgery*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D019380:Anti-HIV Agents