title: Real-time PCR as a prognostic tool for human congenital toxoplasmosis.
abstract: Real-time PCR (qPCR) was positive in 72/150 (48%) blood samples of newborns with congenital toxoplasmosis. Among infants with active retinochoroiditis, 68% had positive qPCR results, while positivity was 29% (P=0.009) in the absence of ocular involvement. Positive qPCR was associated with the presence of retinochoroidal lesions, with an odds ratio of 2.8.
authors.affiliation: Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Júlia Gatti Ladeia
authors.initials: JG
authors.lastname: Costa
authors.forename: Ana Carolina Aguiar Vasconcelos
authors.initials: AC
authors.lastname: Carneiro
authors.forename: Alice Thomáz
authors.initials: AT
authors.lastname: Tavares
authors.forename: Gláucia Manzan Queiroz
authors.initials: GM
authors.lastname: Andrade
authors.forename: Daniel Vitor
authors.initials: DV
authors.lastname: Vasconcelos-Santos
authors.forename: José Nélio
authors.initials: JN
authors.lastname: Januário
authors.forename: Daniel
authors.initials: D
authors.lastname: Menezes-Souza
authors.forename: Ricardo Toshio
authors.initials: RT
authors.lastname: Fujiwara
authors.forename: Ricardo Wagner Almeida
authors.initials: RW
authors.lastname: Vitor
mesh_terms: D001769:Blood / Q000469:parasitology; D002833:Choroiditis / Q000209:etiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D010274:Parasitology / Q000379:methods*; D060888:Real-Time Polymerase Chain Reaction / Q000379:methods*; D014125:Toxoplasmosis, Congenital / Q000175:diagnosis*