title: Recommendations for the management of candidemia in adults in Latin America. Latin America Invasive Mycosis Network.
abstract: Candidemia is one of the most frequent opportunistic mycoses worldwide. Limited epidemiological studies in Latin America indicate that incidence rates are higher in this region than in the Northern Hemisphere. Diagnosis is often made late in the infection, affecting the initiation of antifungal therapy. A more scientific approach, based on specific parameters, for diagnosis and management of candidemia in Latin America is warranted. 'Recommendations for the diagnosis and management of candidemia' are a series of manuscripts that have been developed by members of the Latin America Invasive Mycosis Network. They aim to provide a set of best-evidence recommendations for the diagnosis and management of candidemia. This publication, 'Recommendations for the management of candidemia in adults in Latin America', was written to provide guidance to healthcare professionals on the management of adults who have, or who are at risk of, candidemia. Computerized searches of existing literature were performed by PubMed. The data were extensively reviewed and analyzed by members of the group. The group also met on two occasions to pose questions, discuss conflicting views, and deliberate on a series of management recommendations. 'Recommendations for the management of candidemia in adults in Latin America' includes prophylaxis, empirical therapy, therapy for proven candidemia, patient work-up following diagnosis of candidemia, duration of candidemia treatment, and central venous catheter management in patients with candidemia. This manuscript is the second of this series that deals with diagnosis and treatment of invasive candidiasis. Other publications in this series include: 'Recommendations for the diagnosis of candidemia in Latin America', 'Recommendations for the management of candidemia in children in Latin America', and 'Recommendations for the management of candidemia in neonates in Latin America'.
authors.affiliation: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Latin America Invasive Mycosis Network. Electronic address: mar.nucci@gmail.com.
authors.forename: Marcio
authors.initials: M
authors.lastname: Nucci
authors.forename: Luis
authors.initials: L
authors.lastname: Thompson-Moya
authors.forename: Manuel
authors.initials: M
authors.lastname: Guzman-Blanco
authors.forename: Iris Nora
authors.initials: IN
authors.lastname: Tiraboschi
authors.forename: Jorge Alberto
authors.initials: JA
authors.lastname: Cortes
authors.forename: Juan
authors.initials: J
authors.lastname: Echevarría
authors.forename: Jose
authors.initials: J
authors.lastname: Sifuentes
authors.forename: Jeannete
authors.initials: J
authors.lastname: Zurita
authors.forename: María E
authors.initials: ME
authors.lastname: Santolaya
authors.forename: Tito
authors.initials: T
authors.lastname: Alvarado Matute
authors.forename: Flavio
authors.initials: F
authors.lastname: de Queiroz Telles
authors.forename: Arnaldo Lopes
authors.initials: AL
authors.lastname: Colombo
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000009:adverse effects / Q000627:therapeutic use; D002175:Candida / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification; D058387:Candidemia / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control; D058365:Candidiasis, Invasive / Q000188:drug therapy / Q000517:prevention & control; D055499:Catheter-Related Infections / Q000188:drug therapy / Q000517:prevention & control; D002986:Clinical Trials as Topic; D003428:Cross Infection / Q000188:drug therapy / Q000517:prevention & control; D019468:Disease Management; D004198:Disease Susceptibility; D042241:Early Diagnosis; D006801:Humans; D007843:Latin America; D009369:Neoplasms / Q000150:complications; D009503:Neutropenia / Q000150:complications; D011183:Postoperative Complications / Q000188:drug therapy / Q000382:microbiology; D012307:Risk Factors
chemical_list: D000935:Antifungal Agents
keywords: Adultos; Adults; América Latina; Candidemia; Latin America; Management; Manejo; Recomendaciones; Recommendations