title: Interstitial granulomatous dermatitis and arthritis revealing oesophageal carcinoma.
abstract: Interstitial granulomatous dermatitis and arthritis (IGDA) is an uncommon clinicopathological condition that may occur in association with a number of systemic disorders. We present a novel case of IGDA in association with oesophageal squamous cell carcinoma (SCC). A 67-year-old man with a 3-month history of arthritis presented with several erythematous indurated plaques on his lateral trunk and arms. An oesophagogastroduodenoscopy showed an irregular mass 20 mm in size in the proximal third of the oesophagus, and on histopathological examination of a biopsy, the mass was identified as a poorly differentiated SCC. Histopathological examination of a skin biopsy found features consistent with interstitial granulomatous dermatitis. The combination of clinicopathological correlation and laboratory findings led to the diagnosis of IGDA. This association has not been previously described, to our knowledge.
authors.affiliation: 1Department of Dermatology, University Hospital Virgen de la Victoria, Málaga, Spain. blankitamoyano@hotmail.es
authors.forename: B
authors.initials: B
authors.lastname: Moyano Almagro
authors.forename: N
authors.initials: N
authors.lastname: López Navarro
authors.forename: M
authors.initials: M
authors.lastname: Contreras Steyls
authors.forename: E
authors.initials: E
authors.lastname: Gallego Dominguez
authors.forename: E
authors.initials: E
authors.lastname: Herrera Acosta
authors.forename: E
authors.initials: E
authors.lastname: Herrera Ceballos
mesh_terms: D000368:Aged; D001168:Arthritis / Q000209:etiology*; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D003872:Dermatitis / Q000209:etiology*; D004938:Esophageal Neoplasms / Q000150:complications*; D006099:Granuloma / Q000209:etiology*; D006801:Humans; D008297:Male; D010257:Paraneoplastic Syndromes / Q000473:pathology