title: Presacral tumors: how do they compare in pediatric and adult patients?
abstract: Presacral tumors are rare with few published studies in the literature. It is unknown whether the course of the disease and the required treatment differs between pediatric and adult patients. The aim of the study was to compare presenting symptoms, surgical treatment, pathology, and recurrence rates of presacral tumors in these two groups.
  
  
  METHODS
  An IRB-approved chart review was conducted for patients diagnosed with a presacral tumor at the Cleveland Clinic between 1981 and 2011. Symptoms, physical exam, surgical details, tumor histology, and outcomes were collected as part of the review. Patients were divided into two groups: pediatric (< 18 years n=14) and adult (≥ 18 years n=50).
  
  
  RESULTS
  The most common symptom was a mass in pediatric and pain in adult patients. The most common pediatric primary tumor was a teratoma (n=5, 36%) versus Hamartoma/tailgut cyst (n=17, 34%) in adult patients. Three pediatric and nine adult patients developed tumor recurrences, and 2/14 (14%) pediatric and 4/50 (8%) adult patients developed metastases.
  
  
  CONCLUSIONS
  This study summarizes the presentation, evaluation and management of pediatric and adult presacral tumors at tertiary referral center. The presentation, histology, and management of presacral tumors vary depending upon whether they occur in pediatric or adult patients and recognition of potential differences may influence management.
authors.forename: Craig A
authors.initials: CA
authors.lastname: Messick
authors.forename: Jorge Mario Rosselli
authors.initials: JM
authors.lastname: Londono
authors.forename: Tracy
authors.initials: T
authors.lastname: Hull
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003560:Cysts / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D003952:Diagnostic Imaging / Q000379:methods; D005260:Female; D006222:Hamartoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000601:surgery; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D009442:Neurilemmoma / Q000175:diagnosis / Q000556:secondary / Q000601:surgery; D010386:Pelvic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D011300:Preoperative Care; D012445:Sacrococcygeal Region; D055815:Young Adult