title: Activatable probes based on distance-dependent luminescence associated with Cerenkov radiation.
abstract: Let me get my nanoruler: Activatable probes based on radionuclide and quantum dots (QDs) were constructed using DNA as a linker. Cerenkov radiation from (64)Cu was used to excite the QDs in a distance-dependent manner. The luminescence was lowest nearest to the QD and increased with distance.
authors.affiliation: Department of Radiology, Washington University School of Medicine, 4525 Scott Avenue, St. Louis, MO 63110, USA.
authors.forename: Nalinikanth
authors.initials: N
authors.lastname: Kotagiri
authors.forename: Dariusz M
authors.initials: DM
authors.lastname: Niedzwiedzki
authors.forename: Kohtaro
authors.initials: K
authors.lastname: Ohara
authors.forename: Samuel
authors.initials: S
authors.lastname: Achilefu
mesh_terms: D003301:Copper Radioisotopes / Q000737:chemistry* / Q000378:metabolism; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D049449:Luminescence; D015335:Molecular Probes / Q000737:chemistry* / Q000378:metabolism; D009693:Nucleic Acid Hybridization; D045663:Quantum Dots
chemical_list: D003301:Copper Radioisotopes; D015335:Molecular Probes; D004247:DNA
keywords: Cerenkov radiation; activatable DNA probes; luminescence; nanorulers; quantum dots