title: The anesthetic considerations of intraoperative electrocorticography during epilepsy surgery.
abstract: Epilepsy surgery is a well-established therapeutic intervention for patients with medically refractory seizures. Success of epilepsy surgery depends on the accurate localization and complete removal of the epileptogenic zone. Despite the advances in presurgical localization modalities, electrocorticography is still used in approximately 60% to 70% of the epilepsy centers in North America to guide surgical resection of the epileptogenic lesion and to assess for completeness of surgery. In this review, we discuss the principles and intraoperative use of electrocorticography, the effect of anesthetic drugs on electrocorticography, and the use of pharmacoactivation for intraoperative localization of epileptogenic zone.
authors.affiliation: Department of Anesthesia, Toronto Western Hospital, University Health Network, University of Toronto, 399, Bathurst St., Toronto, Ontario, Canada M5T 2S8.
authors.forename: Jason
authors.initials: J
authors.lastname: Chui
authors.forename: Pirjo
authors.initials: P
authors.lastname: Manninen
authors.forename: Taufik
authors.initials: T
authors.lastname: Valiante
authors.forename: Lashmi
authors.initials: L
authors.lastname: Venkatraghavan
mesh_terms: D000758:Anesthesia / Q000379:methods*; D000777:Anesthetics / Q000009:adverse effects*; D001921:Brain / Q000187:drug effects / Q000503:physiopathology / Q000601:surgery; D001931:Brain Mapping / Q000379:methods*; D058256:Brain Waves / Q000187:drug effects*; D004569:Electroencephalography / Q000379:methods*; D004827:Epilepsy / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D016343:Monitoring, Intraoperative / Q000379:methods*; D019635:Neurosurgical Procedures; D011237:Predictive Value of Tests
chemical_list: D000777:Anesthetics