title: [Comparison of dose calculation algorithms in stereotactic radiation therapy in lung].
abstract: Dose calculation algorithms in radiation treatment planning systems (RTPSs) play a crucial role in stereotactic body radiation therapy (SBRT) in the lung with heterogeneous media. This study investigated the performance and accuracy of dose calculation for three algorithms: analytical anisotropic algorithm (AAA), pencil beam convolution (PBC) and Acuros XB (AXB) in Eclipse (Varian Medical Systems), by comparison against the Voxel Monte Carlo algorithm (VMC) in iPlan (BrainLab). The dose calculations were performed with clinical lung treatments under identical planning conditions, and the dose distributions and the dose volume histogram (DVH) were compared among algorithms. AAA underestimated the dose in the planning target volume (PTV) compared to VMC and AXB in most clinical plans. In contrast, PBC overestimated the PTV dose. AXB tended to slightly overestimate the PTV dose compared to VMC but the discrepancy was within 3%. The discrepancy in the PTV dose between VMC and AXB appears to be due to differences in physical material assignments, material voxelization methods, and an energy cut-off for electron interactions. The dose distributions in lung treatments varied significantly according to the calculation accuracy of the algorithms. VMC and AXB are better algorithms than AAA for SBRT.
authors.affiliation: Graduate School of Health Science, Kumamoto University.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Tomiyama
authors.forename: Fujio
authors.initials: F
authors.lastname: Araki
authors.forename: Nagisa
authors.initials: N
authors.lastname: Kanetake
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Shimohigashi
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Tominaga
authors.forename: Jyunichi
authors.initials: J
authors.lastname: Sakata
authors.forename: Takeshi
authors.initials: T
authors.lastname: Oono
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Kouno
authors.forename: Kazunari
authors.initials: K
authors.lastname: Hioki
mesh_terms: D000465:Algorithms; D006801:Humans; D008168:Lung / Q000528:radiation effects*; D009010:Monte Carlo Method; D016634:Radiosurgery; D011879:Radiotherapy Dosage