title: Directed studies towards the total synthesis of (+)-13-deoxytedanolide: simple and convenient synthesis of the C8-C16 fragment.
abstract: A straightforward synthesis of the enantioenriched C8-C16 south part of (+)-13-deoxytedanolide has been reported. The strength of this approach relies on the preparation of similar functionalized fragments via the transformation of a unique dihydrofuran building block through a 1,2-metallate rearrangement.
authors.affiliation: Aix Marseille Université, CNRS, iSm2 UMR 7313, 13397 Marseille, France.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Meiries
authors.forename: Alexandra
authors.initials: A
authors.lastname: Bartoli
authors.forename: Mélanie
authors.initials: M
authors.lastname: Decostanzi
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Parrain
authors.forename: Laurent
authors.initials: L
authors.lastname: Commeiras
mesh_terms: D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D013237:Stereoisomerism
chemical_list: C409106:13-deoxytedanolide; D018942:Macrolides