title: Physiology of ADP-ribosylation.
abstract: ADP-ribosylation of proteins is a versatile post-translational modification that can alter the chemistry of a specific side chain or provide a handle for the binding of a recognition domain. A better understanding of ADP-ribosylating enzymes and their targets is opening new therapeutic opportunities. This minireview series focuses on physiological aspects of ADP-ribosylation, while a companion series focuses on drug targets.
authors.affiliation: University Medical Center Hamburg, Hamburg, Germany.
authors.forename: Friedrich
authors.initials: F
authors.lastname: Koch-Nolte
authors.forename: Mathias
authors.initials: M
authors.lastname: Ziegler
mesh_terms: D036002:ADP Ribose Transferases / Q000378:metabolism; D000246:Adenosine Diphosphate Ribose / Q000378:metabolism*; D000818:Animals; D006801:Humans; D011499:Protein Processing, Post-Translational / Q000502:physiology*
chemical_list: D000246:Adenosine Diphosphate Ribose; D036002:ADP Ribose Transferases