title: Cumulative live birth rate after three ovarian stimulation IVF cycles for poor ovarian responders according to the bologna criteria.
abstract: This study explored the cumulative live birth rate after three ovarian stimulation in vitro fertilization (IVF) cycles for poor ovarian responders according to the Bologna criteria. In this retrospective cohort study, 479 poor ovarian responders according to the Bologna criteria in the first ovarian stimulation IVF cycle between July 2006 and January 2012 in our IVF centre were included. The cumulative live birth rate was calculated by optimistic and pessimistic methods. The cumulative live birth rate after three ovarian stimulation IVF cycles for poor ovarian responders according to the Bologna criteria was 12.7%-20.5%. The three-cycle cumulative live birth rate was 18.5%-24.5%, 13.2%-27.4% and 8.6%-14.9% for poor responders aged ≤35 years, 36-39 years and ≥40 years, respectively. In conclusion, poor responders according to the Bologna criteria can receive an acceptable cumulative live birth rate after three ovarian stimulation IVF cycles, especially poor responders aged <40 years.
authors.affiliation: Centre for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Ke
authors.affiliation: Centre for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Chen
authors.affiliation: Centre for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
authors.forename: Yu-Dong
authors.initials: YD
authors.lastname: Liu
authors.affiliation: Centre for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
authors.forename: De-Sheng
authors.initials: DS
authors.lastname: Ye
authors.affiliation: Centre for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
authors.forename: Yu-Xia
authors.initials: YX
authors.lastname: He
authors.affiliation: Centre for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. chensl_92@163.com.
authors.forename: Shi-Ling
authors.initials: SL
authors.lastname: Chen
mesh_terms: D000328:Adult; D002681:China / Q000453:epidemiology; D005260:Female; D005307:Fertilization in Vitro / Q000706:statistics & numerical data*; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology* / Q000628:therapy*; D050498:Live Birth / Q000453:epidemiology*; D008875:Middle Aged; D010062:Ovulation Induction / Q000706:statistics & numerical data*; D011247:Pregnancy; D016896:Treatment Outcome; D055815:Young Adult