title: Copper-catalyzed direct synthesis of iodoenamides from ketoximes.
abstract: Iodide in copper's pathway: A new, efficient, and practical copper-catalyzed synthesis of Z-iodoenamides from readily available ketoximes has been developed (see scheme). The reaction was believed to proceed through a single-electron-transfer pathway. The corresponding Z-iodoenamides have been applied to the synthesis of substituted oxazoles, dienes, β-phenoxyl enamides, eneynes, β-acylenamides, and pyrroles (DCE = 1,2-dichloroethane).
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University, Xi'an 710069, PR China.
authors.forename: Hao
authors.initials: H
authors.lastname: Liang
authors.forename: Zhi-Hui
authors.initials: ZH
authors.lastname: Ren
authors.forename: Yao-Yu
authors.initials: YY
authors.lastname: Wang
authors.forename: Zheng-Hui
authors.initials: ZH
authors.lastname: Guan
keywords: asymmetric catalysis; copper; iodoenamides; ketoximes; synthetic methods