title: Post-radiotherapy locoregional recurrence of hyalinizing clear cell carcinoma of palate.
abstract: Clear cell carcinoma of the salivary glands is a rare tumor that represents less than 1% of all salivary tumors and is a new disease that is only recognized in recent years. It is rare and the standard treatment is still under investigation. This tumor often follows an indolent course and treatment includes wide surgical excision with or without adjuvant radiotherapy. Recurrence of the hyalinizing clear cell carcinoma (HCCC) after complete surgical resection is uncommonly documented. We hereby report a case of post-radiotherapy locoregional recurrence of HCCC of the palate and recommend further clinicopathological study and long-term follow-up to document the biological behavior of this entity along with highlighting the role of special stains and immunohistochemistry in its diagnosis.
authors.affiliation: Department of Pathology, R G Kar Medical College & Hospital, Kolkata, India.
authors.forename: Sonia
authors.initials: S
authors.lastname: Gon
authors.forename: Aditi
authors.initials: A
authors.lastname: Bhattacharyya
authors.forename: Bipasa
authors.initials: B
authors.lastname: Majumdar
authors.forename: Tushar K
authors.initials: TK
authors.lastname: Das
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000378:metabolism / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D000368:Aged; D005260:Female; D006801:Humans; D006818:Hyalin / Q000378:metabolism*; D007150:Immunohistochemistry; D009062:Mouth Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000378:metabolism / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D010159:Palate / Q000378:metabolism / Q000473:pathology*