title: Hemodialysis membranes for acute and chronic renal insufficiency.
abstract: As an incomplete renal replacement for the patients with either acute or chronic renal failure, membrane-based hemodialysis therapy is progressing rapidly. However, the mortality and morbidity remain unacceptably high. Much effort has been put into improving the biocompatibility of the hemodialysis membranes. To effectively remove small solutes and 'middle molecules' in compact cartridges, the hydraulic and permselective properties of the hemodialysis membranes have also been deeply investigated. An overview of recent progress of different kinds of hemodialysis membranes and their preparation technology, as well as their modification techniques, is presented. The advantages and deficiencies of many synthetic membranes, including cellulose, cellulose acetate (CA), chitosan (CS), polysulfone (PS), poly(ether sulfone) (PES), polyacrylonitrile (PAN), ethylene-vinyl alcohol copolymer (EVOH), poly (methyl methacrylate) (PMMA) and poly(vinyl alcohol) (PVA), etc. are elaborated upon.
authors.affiliation: Key Laboratory of Resources Chemistry of Nonferrous Metals, Ministry of Education (Central South University), Changsha, Hunan 410083, China. yujg_zhoufl@yahoo.com
authors.forename: Jin-Gang
authors.initials: JG
authors.lastname: Yu
authors.forename: Lin-Yan
authors.initials: LY
authors.lastname: Yu
authors.forename: Xin-Yu
authors.initials: XY
authors.lastname: Jiang
authors.forename: Xiao-Qing
authors.initials: XQ
authors.lastname: Chen
authors.forename: Li-Jian
authors.initials: LJ
authors.lastname: Tao
authors.forename: Fei-Peng
authors.initials: FP
authors.lastname: Jiao
mesh_terms: D000208:Acute Disease; D000818:Animals; D002482:Cellulose / Q000737:chemistry / Q000378:metabolism; D048271:Chitosan / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D008567:Membranes, Artificial; D006435:Renal Dialysis / Q000295:instrumentation / Q000379:methods*; D051436:Renal Insufficiency, Chronic / Q000378:metabolism / Q000628:therapy*
chemical_list: D008567:Membranes, Artificial; D002482:Cellulose; D048271:Chitosan