title: Functional outcome of microsurgical clipping compared to endovascular coiling.
abstract: Endovascular coiling has been used increasingly as an alternative to neurosurgical clipping for treating subarachnoid hemorrhage secondary to aneurysm rupture. In a retrospective cohort review on the treatment methods of aneurysm rupture in Hospital Kuala Lumpur over the period of five years (2005-2009) a total of 268 patients were treated. These patients were broadly categorized into two groups based on their treatment mode for ruptured aneurysms. Statistical analysis was determined using Chi- Square tests to study these associations. In our study, 67.5% of patients presented with Good World Federation of Neurosurgical Societies (WFNS) grade (WFNS1-2) while 32.5% patients presented with Poor WFNS prior to intervention. In our outcome, it was noted that 60.4% had good functional outcome (mRS grade 0-2) as compared to 39.6% patients who had poor mRS(modified rankin scale) outcome (mRS 3-6). In the good WFNS group, 76% of patients in clipping group had a good mRS outcome while, 86.5% patients in coiling group had good mRS outcome (p=0.114). In poor WFNS presentation, it was noted that in 77.3% patients in clipping group, had poor mRS outcome. Similarly with poor WFNS presentation, 83.3% of patient in coiling group had poor outcome. (p=1.00). Hence when we control the WFNS group, there was no significant association between treatment group (clipping and coiling) and mRS outcome at 6 months. The outcome of patient is determined by initial clinical presentation (WFNS grade) and influenced by requirement of Extraventricular drain (EVD) in presence of hydrocephalus, CSF infection and pneumonia. Therefore the decision regarding treatment option needs to be individualized based on the presentation of the patient.
authors.affiliation: Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia. drmpremraja@gmail.com.
authors.forename: R M
authors.initials: RM
authors.lastname: Premananda
authors.forename: N
authors.initials: N
authors.lastname: Ramesh
authors.forename: K P
authors.initials: KP
authors.lastname: Hillol
mesh_terms: D017542:Aneurysm, Ruptured; D004621:Embolization, Therapeutic; D006801:Humans; D012189:Retrospective Studies; D013345:Subarachnoid Hemorrhage; D016896:Treatment Outcome