title: Primary neuroendocrine mediastinal tumor presenting with carcinoid syndrome and left supraclavicular lymphadenopathy: clinico-radiological and pathological features.
abstract: Primary mediastinal neuro-endocrine tumor is very rare. The primary modality to evaluate the lesion is computed tomography, to know disease extent, involvement of various structures, vascular invasion and metastasis. Histo-pathological and immuno-histochemical confirmation is mandatory. We report a rare case of primary neuroendocrine mediastinal tumor/atypical carcinoid in a young male who presented with carcinoid syndrome and left supraclavicular lymphadenopathy. Complete diagnostic work up was done followed by histo-pathological and immuno-histochemical confirmation. Later on patient underwent radical surgery followed by chemotherapy. The patient is currently on follow up. Neuroendocrine carcinoma of the thymus generally follows an aggressive clinical course.The biologic behavior is directly related to grade and degree of differentiation. This case report of primary low grade neuroendocrine tumor/atypical carcinoid adds to the biological behavior of this tumor and sheds light on the radiological and pathological features of neuroendocrine carcinomas.
authors.affiliation: Department of Radiodiagnosis and Imaging, Institute of Medical Sciences, Banaras Hindu University,Varanasi, Uttar Pradesh, India.
authors.forename: Amit Nandan D
authors.initials: AN
authors.lastname: Dwivedi
authors.forename: Kanika
authors.initials: K
authors.lastname: Goel
authors.forename: Suchi
authors.initials: S
authors.lastname: Tripathi
authors.forename: Sunny
authors.initials: S
authors.lastname: Garg
authors.forename: Madhukar
authors.initials: M
authors.lastname: Rai
mesh_terms: D000328:Adult; D006801:Humans; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008303:Malignant Carcinoid Syndrome / Q000000981:diagnostic imaging / Q000473:pathology*; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography