title: Switchable catalytic activity: selenium-containing peptides with redox-controllable self-assembly properties.
abstract: Mimicking nature: The reversible formation of self-assembled nanostructures of selenium-containing peptides can be controlled by redox triggers (see scheme, VC = vitamin C). As a consequence, the catalytic activity of these peptides is switchable. These results should lead to the development of nature-mimicking smart materials with promising properties.
authors.affiliation: State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin 300071, PR China.
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Miao
authors.forename: Wei
authors.initials: W
authors.lastname: Cao
authors.forename: Wenting
authors.initials: W
authors.lastname: Zheng
authors.forename: Jingyu
authors.initials: J
authors.lastname: Wang
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Gao
authors.forename: Chengbiao
authors.initials: C
authors.lastname: Yang
authors.forename: Deling
authors.initials: D
authors.lastname: Kong
authors.forename: Huaping
authors.initials: H
authors.lastname: Xu
authors.forename: Ling
authors.initials: L
authors.lastname: Wang
authors.forename: Zhimou
authors.initials: Z
authors.lastname: Yang
mesh_terms: D016475:3T3 Cells; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D001205:Ascorbic Acid / Q000494:pharmacology*; D002942:Circular Dichroism; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D020100:Hydrogels / Q000737:chemistry* / Q000378:metabolism; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D051379:Mice; D049329:Nanostructures / Q000737:chemistry*; D016877:Oxidants / Q000494:pharmacology; D010084:Oxidation-Reduction; D010446:Peptide Fragments / Q000737:chemistry* / Q000378:metabolism; D012643:Selenium / Q000737:chemistry* / Q000378:metabolism
chemical_list: D000975:Antioxidants; D020100:Hydrogels; D016877:Oxidants; D010446:Peptide Fragments; D006861:Hydrogen Peroxide; D012643:Selenium; D001205:Ascorbic Acid
keywords: hydrogels; peptides; redox chemistry; selenium; self-assembly