title: [Update of multifocal motor neuropathy].
abstract: We surveyed patients with multifocal motor neuropathy (MMN) in comparison with those with amyotrophic lateral sclerosis (ALS) in Japan. This retrospective study consisted of 47 patients with MMN and 1,051 patients with ALS from major neuromuscular centers in Japan from 2005 to 2009. The ratio of MMN to ALS patients (0-0.10) varied among the centers, but mostly converged to 0.05. The prevalence was estimated to be 0.3 cases for MMN and 6.63 cases for ALS per 100,000 persons. Twenty-seven of 47 patients (56.5%) showed conduction block (CB). Of the 45 patients who received intravenous immunoglobulin (MVg), 34(75.6 %) demonstrated clear clinical improvement.
authors.affiliation: Department of Neurology, Institute of Health Bioscience, Tokushima University Graduate School of Medicine.
authors.forename: Naoko
authors.initials: N
authors.lastname: Matsui
authors.forename: Ai
authors.initials: A
authors.lastname: Miyashiro
authors.forename: Ryuji
authors.initials: R
authors.lastname: Kaji
mesh_terms: D017677:Age Distribution; D000690:Amyotrophic Lateral Sclerosis / Q000188:drug therapy / Q000453:epidemiology*; D003937:Diagnosis, Differential; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007564:Japan / Q000453:epidemiology; D011115:Polyneuropathies / Q000188:drug therapy* / Q000453:epidemiology*
chemical_list: D016756:Immunoglobulins, Intravenous