title: Full genomic characterization of a group C rotavirus isolated from a child in South Korea.
abstract: During an epidemiological survey of human rotavirus infection in Seoul, Korea, from 2010 to 2011, one isolate of group C rotavirus (GCRV), named CAU10-312, was detected in a 5-year-old child admitted to the hospital with acute gastroenteritis, and its complete genomic sequence was determined. The 11 gene segments of the strain possessed G4-P[2]-I2-R2-C2-M2-A2-N2-T2-E2-H2 genotypes. The genotype of strain CAU10-312 appears to be closely related to strains from Bangladesh (DhakaC13 and BS347), India (v508), and England (Bristol), but distinct from Far East Asian strains, Chinese (Wu82 and YNR001) and Japanese (OH567 and BK0830). These findings may clarify the relationship of the genetics, evolutionary biology, and epidemiology of GCRVs and suggest that two very distinct genotype strains are in circulation in the world.
authors.affiliation: Department of Microbiology and Research Center for Medical Sciences, Chung-Ang University College of Medicine, Seoul, South Korea.
authors.forename: In Hyuk
authors.initials: IH
authors.lastname: Baek
authors.forename: Van Thai
authors.initials: VT
authors.lastname: Than
authors.forename: Hakyoung
authors.initials: H
authors.lastname: Kim
authors.forename: Inseok
authors.initials: I
authors.lastname: Lim
authors.forename: Wonyong
authors.initials: W
authors.lastname: Kim
mesh_terms: D002648:Child; D016000:Cluster Analysis; D005759:Gastroenteritis / Q000821:virology; D016679:Genome, Viral; D005838:Genotype; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics*; D056910:Republic of Korea; D012401:Rotavirus / Q000235:genetics* / Q000302:isolation & purification; D012400:Rotavirus Infections / Q000821:virology; D017422:Sequence Analysis, DNA; D017385:Sequence Homology
chemical_list: D012367:RNA, Viral