title: [Investigation of 24-hour blood pressure monitoring for evaluating treatment outcome of nerve-mediated syncope in children].
abstract: OBJECTIVE
  To investigate the clinical significance of 24-hour blood pressure monitoring (ABPM) for evaluating the treatment outcome of nerve-mediated syncope (NMS) in children.
  
  
  METHODS
  Twenty-eight children with NMS confirmed by a head-up tilt table test (HUTT) (12 males and 16 females, aged 6-13 years) and with a chief complaint of unexplained syncope or pre-syncope between February 2010 and August 2012, were included in the study. These children received health education combined with therapy using oral rehydration salts solution and were then reexamined for clinical symptoms as well as HUTT and ABPM results.
  
  
  RESULTS
  Of 28 NMS cases, 22 were vasodepressive type, 5 were mixed type, and 1 was cardioinhibitory type. The follow-up showed that 27 (96%) of all cases had improved clinical symptoms, and 18 (64%) had improved HUTT results. The ABPM follow-up revealed no significant changes in 24-hour mean systolic pressure, 24-hour mean diastolic pressure, daytime mean systolic pressure, daytime mean diastolic pressure, nighttime mean systolic pressure, nighttime mean diastolic pressure, day-night difference of systolic pressure, and day-night difference of diastolic pressure after treatment (P>0.05). The percentage of children with a dipper blood pressure pattern increased from 29% (8/28) before treatment to 50% (14/28) after treatment; the percentage of children with a non-dipper blood pressure pattern decreased from 71% (20/28) before treatment to 50% (14/28) after treatment.
  
  
  CONCLUSIONS
  As an effective, objective and non-invasive monitoring means, ABPM is of some clinical significance for evaluating the treatment outcome of NMS in children.
authors.affiliation: Department of Pediatric Cardiovasology, Second Xiangya Hospital of Central South University, Changsha, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Xu
authors.forename: Ping
authors.initials: P
authors.lastname: Lin
authors.forename: Cheng
authors.initials: C
authors.lastname: Wang
authors.forename: Li-Jia
authors.initials: LJ
authors.lastname: Wu
authors.forename: Mei-Hua
authors.initials: MH
authors.lastname: Kang
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Zhu
authors.forename: Fang
authors.initials: F
authors.lastname: Li
authors.forename: Yun-Li
authors.initials: YL
authors.lastname: Li
authors.forename: Wei-Hong
authors.initials: WH
authors.lastname: Chu
authors.forename: Jing
authors.initials: J
authors.lastname: Ran
mesh_terms: D000293:Adolescent; D018660:Blood Pressure Monitoring, Ambulatory; D002648:Child; D005260:Female; D006266:Health Education; D006801:Humans; D008297:Male; D015532:Rehydration Solutions / Q000008:administration & dosage; D013575:Syncope / Q000503:physiopathology* / Q000628:therapy; D018667:Tilt-Table Test; D016896:Treatment Outcome
chemical_list: D015532:Rehydration Solutions