title: How can innovative forms of clinical research contribute to deliver affordable cancer care in an evolving health care environment?
abstract: As health care costs are constantly rising and governments are reforming their healthcare systems there is an urgent need to reshape the European clinical research landscape. To bridge the translational gap extensive research to understand the mechanism of the agents and of the disease has to be performed and the real benefit of drugs needs to be assessed independently. Furthermore, meaningful data for reimbursement strategies will be a major goal of future clinical trials as well. Therefore, a new integrated model of clinical cancer research is needed to optimise the R&D process. Strategies to ensure that we can gather robust and relevant data about the effectiveness of various healthcare interventions have to be developed to provide optimal patient care within the limits of a healthcare budget.
authors.affiliation: EORTC Headquarters, Avenue E. Mounier 83/11, 1200 Brussels, Belgium.
authors.forename: Susen
authors.initials: S
authors.lastname: Burock
authors.forename: Françoise
authors.initials: F
authors.lastname: Meunier
authors.forename: Denis
authors.initials: D
authors.lastname: Lacombe
mesh_terms: D000970:Antineoplastic Agents / Q000191:economics / Q000627:therapeutic use*; D002017:Budgets / Q000639:trends; D002986:Clinical Trials as Topic / Q000191:economics / Q000639:trends; D003695:Delivery of Health Care / Q000191:economics / Q000639:trends*; D004059:Diffusion of Innovation; D016527:Drug Costs; D055808:Drug Discovery / Q000191:economics / Q000639:trends; D017048:Health Care Costs / Q000639:trends*; D018166:Health Care Reform / Q000191:economics / Q000639:trends*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D057285:Precision Medicine / Q000191:economics / Q000639:trends; D055818:Public-Private Sector Partnerships / Q000191:economics / Q000639:trends; D012052:Reimbursement, Incentive / Q000191:economics / Q000639:trends; D012109:Research Support as Topic / Q000639:trends; D057170:Translational Research, Biomedical / Q000191:economics / Q000639:trends*
chemical_list: D000970:Antineoplastic Agents
keywords: Clinical trials; Observational cohort studies; Pay for performance; Public private partnership; Real life data