title: Prevalence of hepatitis E and hepatitis B dual infection in North India (Delhi).
abstract: OBJECTIVE
  The prevalence of dual infection was 2.8% (26/927). Majority of these patients had presented with acute flare of a chronic liver disease (42.3%) followed by acute jaundice (38.5%).We found HEV infection to be was highly prevalent among 20 to 40 years of age group. In the case of HBV only 5.37% (5/93) children were affected in the age group 0-10 years.
  
  
  METHODS
  Serum samples from 1147 proven HEV infection suspected were collected and tested for HBsAg and HEV (IgM) antibodies using enzyme linked immunosorbent assay kits (bio Merieux, France).
  
  
  RESULTS
  There were the 32.16% (367/1141) HEV positive cases. We found maximum HEV positivity in the age group of 21-30 years. There were 2.8% (26/927) HEV and HBV dully infected patients. The total 44.68% (273/611) suspected of acute hepatitis/jaundice were HEV positive.
  
  
  CONCLUSIONS
  The HEV found to be was highly prevalent among 20 to 40 years of age group. The males were more frequent than females for HEV and HBV infection. In the children's, there were lower attack of both HEV and HBV. The maximum patients were having acute hepatitis/jaundice in both HEV and HBV infection. There were 26 dually infected patients in 12 months.
authors.affiliation: Department of Microbiology, C.C.S. University, Meerut-250005, India.
authors.forename: Nim J
authors.initials: NJ
authors.lastname: Singh
authors.forename: Archana
authors.initials: A
authors.lastname: Kumari
authors.forename: Roberto
authors.initials: R
authors.lastname: Catanzaro
authors.forename: Francesco
authors.initials: F
authors.lastname: Marotta
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D060085:Coinfection / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D019353:Endemic Diseases; D005260:Female; D006509:Hepatitis B / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology*; D016751:Hepatitis E / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D017678:Sex Distribution; D055815:Young Adult