title: Primary CNS lymphoplasmacytic lymphoma: a case report and review of literature.
abstract: Lymphoplasmacytic lymphoma is a chronic lymphoproliferative disorder characterized by a proliferation of plasma cells, small lymphocytes, plasmacytoid lymphocytes and the production of monoclonal IgM. Primary central nervous system lymphomas (PCNSL) are rare non-Hodgkin lymphomas (NHL) that can be found in the brain, leptomeninges, eyes or spinal cord, and are mostly intracerebral. PCNSLs constitute 3-4% of primary brain tumors, and in most cases are diffuse large B-cell lymphomas (DLBCL).(1) Low grade lymphomas as primary central nervous system (CNS) lymphoma are very rare. We present here a case report of a woman who presented with headache and was found to have primary intracranial lymphoplasmacytic lymphoma (LPL).
authors.affiliation: Division of Hematology and Oncology, Department of Medicine, University of Toledo Medical Center, Toledo, OH 43614, USA. dockamalkant@gmail.com
authors.forename: Kamal K S
authors.initials: KK
authors.lastname: Abbi
authors.forename: Mahvish
authors.initials: M
authors.lastname: Muzaffar
authors.forename: Daniel
authors.initials: D
authors.lastname: Gaudin
authors.forename: Robert L
authors.initials: RL
authors.lastname: Booth
authors.forename: John J
authors.initials: JJ
authors.lastname: Feldmeier
authors.forename: Roland T
authors.initials: RT
authors.lastname: Skeel
mesh_terms: D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000532:radiotherapy; D005260:Female; D005720:Gamma Rays; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000532:radiotherapy; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D064847:Multimodal Imaging; D010950:Plasma Cells / Q000378:metabolism / Q000473:pathology; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed