title: Associations of periodontitis and oral manifestations with CD4 counts in human immunodeficiency virus-pregnant women in Thailand.
abstract: OBJECTIVE
  To investigate the associations of CD4 count with chronic periodontitis and human immunodeficiency virus (HIV)-related oral lesions in pregnant HIV-infected Thai women.
  
  
  METHODS
  Two hundred ninety-two HIV-infected pregnant women were interviewed for health information and examined for their periodontal condition and HIV-related oral lesions during weeks 16-34 of gestation. Logistic regression, t tests and Chi-squared tests were used to examine the associations of CD4 count with oral lesions and periodontal conditions.
  
  
  RESULTS
  One hundred thirty-three women (45.6%) had at least 1 tooth with a periodontal pocket over 4 mm. Thirty-eight (17.76%) subjects had oral candidiasis and 53 subjects (24.77%) had oral hairy leukoplakia (OHL). Low CD4 count was significantly associated with periodontitis at odds ratio (OR) = 2.06 with 95% confidence interval (CI) = [1.00-4.27], P = .05. A significant association was found for low CD4 count with OHL with OR = 3.57, 95% CI = [1.34-9.46], P = .01.
  
  
  CONCLUSIONS
  Chronic periodontitis and OHL were associated with CD4 count lower than 200 cells/mm(3) in HIV-infected women.
authors.affiliation: Faculty of Dentistry, Thammasat University, Pathumthani, Thailand. ppakkaporn@yahoo.com
authors.forename: Pakkaporn
authors.initials: P
authors.lastname: Pattrapornnan
authors.forename: Timothy A
authors.initials: TA
authors.lastname: DeRouen
mesh_terms: D000293:Adolescent; D000328:Adult; D015704:CD4 Antigens / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000097:blood* / Q000503:physiopathology; D006801:Humans; D016015:Logistic Models; D009055:Mouth / Q000473:pathology*; D010518:Periodontitis / Q000097:blood* / Q000145:classification / Q000453:epidemiology; D011247:Pregnancy; D015995:Prevalence; D013785:Thailand / Q000453:epidemiology
chemical_list: D015704:CD4 Antigens