title: UK Renal Registry 15th annual report: Chapter 7 clinical, haematological and biochemical parameters in patients receiving renal replacement therapy in paediatric centres in the UK in 2011: national and centre-speciﬁc analyses.
abstract: BACKGROUND
  The British Association for Paediatric Nephrology Registry was established to analyse data related to renal replacement therapy (RRT) in children. The registry receives data from the 13 paediatric nephrology centres in the UK.
  
  
  OBJECTIVE
  To provide centre speciﬁc data so that individual centres can reﬂect on the contribution that their data makes to the national picture and to determine the extent to which their patient parameters meet nationally agreed audit standards for the management of children with established renal failure.
  
  
  METHODS
  Data returns have been a mixture of electronic and paper returns. Data were analysed to calculate summary statistics and where applicable the percentage achieving an audit standard. The standards used were those set out by the Renal Association and the National Institute for Health and Clinical Excellence.
  
  
  RESULTS
  Anthropometric data conﬁrmed that children receiving RRT were short compared to healthy peers. Amongst patients with a height of <2 SD between 2001 and 2011, 31% were receiving growth hormone if they were on dialysis compared to 10% if they had a functioning transplant. Blood pressure control remained challenging with wide inter-centre variation although this was signiﬁcantly better in children with a functioning transplant. Over a third of haemodialysis patients and a quarter of peritoneal dialysis patients were anaemic, compared to only 7% of transplanted patients. ESA use in the dialysis population exceeded 90% amongst anaemic patients. The control of renal bone disease remained challenging.
  
  
  CONCLUSIONS
  Optimizing growth in children on RRT remained challenging and the control of bone biochemistry in children on dialysis was imperfect. The likelihood of complete electronic reporting in the near future with plans for quarterly reporting in the format of the recently ﬁnalised NEW paediatric dataset will hopefully improve quality of data and their reporting, allowing improvements in patient care.
authors.affiliation: UK Renal Registry, Bristol, UK.
authors.forename: Rishi
authors.initials: R
authors.lastname: Pruthi
authors.forename: Heather
authors.initials: H
authors.lastname: Maxwell
authors.forename: Anna
authors.initials: A
authors.lastname: Casula
authors.forename: Fiona
authors.initials: F
authors.lastname: Braddon
authors.forename: Malcolm
authors.initials: M
authors.lastname: Lewis
authors.forename: Catherine
authors.initials: C
authors.lastname: O'Brien
authors.forename: Yincent
authors.initials: Y
authors.lastname: Tse
authors.forename: Carol
authors.initials: C
authors.lastname: Inward
authors.forename: Manish D
authors.initials: MD
authors.lastname: Sinha
mesh_terms: D000293:Adolescent; D000847:Annual Reports as Topic; D015984:Causality; D002648:Child; D002675:Child, Preschool; D005260:Female; D006306:Health Surveys; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000453:epidemiology* / Q000534:rehabilitation*; D008297:Male; D009398:Nephrology / Q000706:statistics & numerical data / Q000639:trends; D015995:Prevalence; D012042:Registries; D017582:Renal Replacement Therapy / Q000706:statistics & numerical data*; D012307:Risk Factors; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D006454:Hemoglobins