title: Argyria -- case report.
abstract: A 70-year-old male rural worker was referred to our clinic with widespread grey pigmentation of the skin and nails. The condition had been asymptomatic for its entire duration (5 years). He reported past intranasal application of 10% Silver Vitellinate. A skin biopsy was performed and histology corroborated the clinical diagnosis of Argyria. This case represents a currently rare dermatological curiosity. Although silver colloids and salts have been withdrawn and/or banned by some drug surveillance agencies, they continue to be freely sold and unregulated as food supplements and as ingredients in alternative medicines, thereby risking the emergence of new cases of silver poisoning.
authors.affiliation: Dermatology Service of the Santo Antonio dos Capuchos Hospital – Central Lisbon Hospital Center (E.P.E) – Lisbon, Portugal. lencastre.derm@gmail.com
authors.forename: André
authors.initials: A
authors.lastname: Lencastre
authors.forename: Maria
authors.initials: M
authors.lastname: Lobo
authors.forename: Alexandre
authors.initials: A
authors.lastname: João
mesh_terms: D000368:Aged; D001129:Argyria / Q000473:pathology*; D001706:Biopsy; D003937:Diagnosis, Differential; D004439:Eccrine Glands / Q000473:pathology; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology*