title: Bilateral diffuse iris atrophy after the use of oral clarithromycin.
abstract: OBJECTIVE
  To report a newly recognised advert event of clarithromycin.
  
  
  METHODS
  Retrospective, case report.
  
  
  RESULTS
  A 30-year old female referred to our centre with bilateral diffuse iris atrophy after the use of oral clarithromycin for a pulmonary infection.
  
  
  CONCLUSIONS
  Bilateral acute depigmentation of the iris is a new clinical entity. Iris transillumination and sphincter paralysis are recognised adverse effects of oral antibiotic therapy, but to our knowledge no other publication has referred to uveitis-like syndrome due to oral administration of clarithromycin.
authors.affiliation: Retina Eye Center , Thessaloniki , Greece .
authors.forename: Paris
authors.initials: P
authors.lastname: Tranos
authors.forename: Mayssa B
authors.initials: MB
authors.lastname: Nasr
authors.forename: Solon
authors.initials: S
authors.lastname: Asteriades
authors.forename: Athanasios
authors.initials: A
authors.lastname: Vakalis
authors.forename: Ilias
authors.initials: I
authors.lastname: Georgalas
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001284:Atrophy; D017291:Clarithromycin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007498:Iris / Q000187:drug effects / Q000473:pathology; D007499:Iris Diseases / Q000139:chemically induced* / Q000473:pathology; D018410:Pneumonia, Bacterial / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D017291:Clarithromycin