title: A chemically reactive Raman probe for ultrasensitively monitoring and imaging the in vivo generation of femtomolar oxidative species as induced by anti-tumor drugs in living cells.
abstract: A chemically reactive Raman probe has been developed for ultrasensitively monitoring and imaging the in vivo generation of femtomolar oxidative species as induced by anti-tumor drugs in living cells.
authors.affiliation: Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei, Anhui, China. cljiang@iim.ac.cn
authors.forename: Changlong
authors.initials: C
authors.lastname: Jiang
authors.forename: Renyong
authors.initials: R
authors.lastname: Liu
authors.forename: Guangmei
authors.initials: G
authors.lastname: Han
authors.forename: Zhongping
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry*; D015374:Biosensing Techniques; D045744:Cell Line, Tumor; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry; D015394:Molecular Structure; D011092:Polyethylene Glycols / Q000737:chemistry; D017382:Reactive Oxygen Species / Q000032:analysis* / Q000378:metabolism*; D012235:Rhodamines / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D013059:Spectrum Analysis, Raman
chemical_list: D000970:Antineoplastic Agents; D005456:Fluorescent Dyes; D017382:Reactive Oxygen Species; D012235:Rhodamines; C058319:dihydrorhodamine 123; D012834:Silver; D011092:Polyethylene Glycols