title: Biology of tooth replacement in amniotes.
abstract: Tooth replacement is a common trait to most vertebrates, including mammals. Mammals, however, have lost the capacity for continuous tooth renewal seen in most other vertebrates, and typically have only 1-2 generations of teeth. Here, we review the mechanisms of tooth replacement in reptiles and mammals, and discuss in detail the current and historical theories on control of timing and pattern of tooth replacement and development.
authors.affiliation: Department of Oral Health Sciences, University of British Columbia, Vancouver, Canada.
authors.forename: John A
authors.initials: JA
authors.lastname: Whitlock
authors.forename: Joy M
authors.initials: JM
authors.lastname: Richman
mesh_terms: D000818:Animals; D001695:Biology; D006801:Humans; D008322:Mammals / Q000502:physiology*; D009805:Odontogenesis / Q000235:genetics / Q000502:physiology*; D012104:Reptiles / Q000502:physiology*; D014070:Tooth / Q000254:growth & development; D014083:Tooth Germ / Q000196:embryology; D014094:Tooth, Deciduous / Q000254:growth & development