title: Computer-aided technology for fabricating complete dentures: systematic review of historical background, current status, and future perspectives.
abstract: BACKGROUND
  Computer-aided technology is an emerging method for fabricating complete dentures. Consolidated information about historical background, current status, and scope for the future is lacking.
  
  
  OBJECTIVE
  The purpose of this systematic review was to analyze the existing literature on computer-aided technology for fabricating complete dentures and provide the reader with a historical background, current status, and future perspectives on this emerging technology.
  
  
  METHODS
  An electronic search of the English language literature between the periods of January 1957 and June 2012 was performed by using PubMed/MEDLINE with the following specific search terms: CAD-CAM complete dentures, digital complete dentures, computer dentures, designed dentures, machined dentures, manufactured dentures, milled dentures, and rapid prototyping dentures. Additionally, the search terms were used on the Google search engine to identify current commercial manufacturers and their protocols.
  
  
  RESULTS
  A total of 1584 English language titles were obtained from the electronic database, and the systematic application of exclusion criteria resulted in the identification of 8 articles pertaining to computer-aided technology for complete dentures. Since the first published report in 1994, multiple authors have described different theoretical models and protocols for fabricating complete dentures with computer-aided technology. Although no clinical trials or clinical reports were identified in the scientific literature, the Google search engine identified 2 commercial manufacturers in the United States currently fabricating complete dentures with computer-aided design and computer-aided manufacturing (CAD/CAM) technology for clinicians world-wide. These manufacturers have definitive protocols in place and offer exclusive dental materials, techniques, and laboratory support. Their protocols contrast with conventional paradigms for fabricating complete dentures and allow the fabrication of complete dentures in 2 clinical appointments.
  
  
  CONCLUSIONS
  A body of scientific literature related to computer-aided technology for complete dentures is emerging. Significant advancements in this technology have now resulted in their commercial availability with shorter clinical protocols. However, prospective clinical trials with true clinical endpoints are necessary to validate this technology. This could affect dental education, patient care, research, and public health worldwide.
authors.affiliation: Department of Reconstructive Sciences, University of Connecticut Health Center, Farmington, CT, USA. avinashbidra@yahoo.com
authors.forename: Avinash S
authors.initials: AS
authors.lastname: Bidra
authors.forename: Thomas D
authors.initials: TD
authors.lastname: Taylor
authors.forename: John R
authors.initials: JR
authors.lastname: Agar
mesh_terms: D017076:Computer-Aided Design; D003779:Denture Design; D003824:Denture, Complete; D006801:Humans