title: Population structure and antimicrobial susceptibility of both nonpersistent and persistent Pseudomonas aeruginosa isolates recovered from cystic fibrosis patients.
abstract: Seventy-six Pseudomonas aeruginosa isolates recovered from chronically (n=18) and nonchronically (n=18) colonized cystic fibrosis (CF) patients (2002 to 2009) were grouped in separate polyclonal populations. International CF epidemic clones were not identified, but the high-risk clone ST274, also found circulating in Spanish hospitals, was present. Persistent isolates were more resistant to antibiotics than nonpersistent isolates.
authors.affiliation: Servicio de Microbiología and Unidad de Resistencia a Antibióticos y Virulencia Bacteriana Asociada al Consejo Superior de Investigaciones Científicas, Hospital Universitario Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Fernández-Olmos
authors.forename: María
authors.initials: M
authors.lastname: García-Castillo
authors.forename: José María
authors.initials: JM
authors.lastname: Alba
authors.forename: María Isabel
authors.initials: MI
authors.lastname: Morosini
authors.forename: Adelaida
authors.initials: A
authors.lastname: Lamas
authors.forename: Beatriz
authors.initials: B
authors.lastname: Romero
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Galán
authors.forename: Rosa
authors.initials: R
authors.lastname: del Campo
authors.forename: Rafael
authors.initials: R
authors.lastname: Cantón
mesh_terms: D001424:Bacterial Infections / Q000453:epidemiology / Q000382:microbiology*; D003550:Cystic Fibrosis / Q000150:complications*; D005838:Genotype; D006801:Humans; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D058889:Molecular Typing; D011550:Pseudomonas aeruginosa / Q000145:classification* / Q000187:drug effects* / Q000302:isolation & purification; D013030:Spain / Q000453:epidemiology