title: Oral manifestations of McCune-Albright syndrome.
abstract: McCune- Albright Syndrome (MAS) is a rare fibrosseous lesion, characterized by a classic triad of polyostotic fibrous dysplasia (PFD), café -au-lait macules (CALM) and underlying endocrinopathies. We present the oral findings of an interesting case of MAS with relevant review of literature. A 30-year-old male presented to us with swelling of both jaws over a period of two years. Cutaneous examination revealed café - au - lait macule over the back, crossing the midline. Skeletal survey showed expansile, osteolytic, mixed radiolucent- radiopaque lesions in skull and jaw bones. Serum alkaline phosphatase was elevated (388 IU/L), with normal calcium, phosphorus, parathyroid hormone and 25 hydroxy vitamin D levels. Diagnosis of McCune- Albright syndrome was made and he was treated with parenteral bisphosphonates (intravenous Zoledronate 4 mg) and is under follow up for surgical recontouring of the jaws. Early recognition facilitates better treatment and improves prognosis by reducing the morbidity.
authors.affiliation: Department of Oral Medicine and Radiology, Career Post Graduate Institute of Dental Sciences and Hospital, Sitapur Road, Lucknow, Uttar Pradesh, India.
authors.forename: Konidena
authors.initials: K
authors.lastname: Aravinda
authors.forename: Pamula
authors.initials: P
authors.lastname: Ratnakar
authors.forename: Kandakurti
authors.initials: K
authors.lastname: Srinivas
keywords: Albright's syndrome; fibroosseous lesion; fibrous dysplasia of the jaws; polyostotic fibrous dysplasia