title: Vaginal discharge in a spayed dog with multiple distinct malignancies.
abstract: BACKGROUND
  An 11-year-old female spayed Labrador Retriever was presented with clinical signs of oestrus and vaginal bleeding. Historically, the dog had not cycled and had been spayed at less than 6 months of age.
  
  
  RESULTS
  Extensive investigation culminated in the diagnosis of an ovarian granulosa cell tumour. The patient had a history of localised grade III mast cell tumour 5 years prior and hepatic haemangiosarcoma 8 months prior to diagnosis.
  
  
  CONCLUSIONS
  Both conditions were successfully treated with a combination of surgery and chemotherapy and there was no evidence of metastasis or recurrence at the time of evaluation for signs of oestrus.
authors.affiliation: Small Animal Specialist Hospital, 1/1 Richardson Place, North Ryde, New South Wales, Australia. nchristensen@sashvets.com
authors.forename: N I
authors.initials: NI
authors.lastname: Christensen
authors.forename: P H
authors.initials: PH
authors.lastname: Brain
authors.forename: V
authors.initials: V
authors.lastname: Langova
authors.forename: A B
authors.initials: AB
authors.lastname: Flory
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology* / Q000628:therapy; D004285:Dogs; D005260:Female; D006106:Granulosa Cell Tumor / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D006651:Histocytochemistry / Q000662:veterinary; D010051:Ovarian Neoplasms / Q000473:pathology / Q000628:therapy / Q000662:veterinary*