title: [Diagnosis of stable coronary artery disease with non-invasive FFR: myth or reality?].
abstract: Decision to revascularize a patient with stable coronary artery disease should be based on the detection of myocardial ischemia. If this decision can be straightforward with significant stenosis or in non-significant stenosis, the decision with intermediate stenosis is far more difficult and require invasive measures of functional impact of coronary stenosis on maximal blood (flow fractional flow reserve=FFR). A recent computer based method has been developed and is able to measure FFR with data acquired during a standard coronary CT-scan (FFRcT). Two recent clinical studies (DeFACTO and DISCOVER-FLOW) show that diagnostic performance of FFRcT was associated with improved diagnostic accuracy versus standard coronary CT-scan for the detection of myocardial ischemia although FFRcT need further development.
authors.affiliation: Unité de cardiologie interventionnelle, Service de cardiologie, CHUV, 1011 Lausanne. maxime.tapponnier@chuv.ch
authors.forename: M
authors.initials: M
authors.lastname: Tapponnier
authors.forename: J-F
authors.initials: JF
authors.lastname: lglesias
authors.forename: E
authors.initials: E
authors.lastname: Eeckhout
authors.forename: O
authors.initials: O
authors.lastname: Muller
mesh_terms: D017023:Coronary Angiography / Q000379:methods*; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D018450:Disease Progression; D053805:Fractional Flow Reserve, Myocardial / Q000502:physiology*; D006801:Humans; D009204:Myocardial Revascularization; D014057:Tomography, X-Ray Computed