title: Vestibular migraine: clinical aspects and pathophysiology.
abstract: Vestibular migraine is becoming recognised as a distinct clinical entity that accounts for a high proportion of patients with vestibular symptoms. A temporal overlap between vestibular symptoms, such as vertigo and head-movement intolerance, and migraine symptoms, such as headache, photophobia, and phonophobia, is a requisite diagnostic criterion. Physical examination and laboratory testing are usually normal in vestibular migraine but can be used to rule out other vestibular disorders with overlapping symptoms. The pathophysiology of vestibular migraine is incompletely understood but plausibly could include neuroanatomical pathways to and from central vestibular structures and neurochemical modulation via the locus coeruleus and raphe nuclei. In the absence of controlled trials, treatment options for patients with vestibular migraine largely mirror those for migraine headache.
authors.affiliation: Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA 15213, USA. furmanjm@upmc.edu
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Furman
authors.forename: Dawn A
authors.initials: DA
authors.lastname: Marcus
authors.forename: Carey D
authors.initials: CD
authors.lastname: Balaban
mesh_terms: D015220:Calcium Channels / Q000235:genetics / Q000502:physiology; D006801:Humans; D008881:Migraine Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics* / Q000503:physiopathology* / Q000628:therapy*; D010808:Physical Examination; D000254:Sodium-Potassium-Exchanging ATPase / Q000235:genetics; D015837:Vestibular Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics* / Q000503:physiopathology* / Q000628:therapy*; D014722:Vestibule, Labyrinth / Q000503:physiopathology
chemical_list: D015220:Calcium Channels; D000254:Sodium-Potassium-Exchanging ATPase