title: Low to intermediate grade salivary duct carcinoma associated with osteoclast like-giant cell tumor of parotid gland: a rare case with distinct pathological features.
abstract: Osteoclast like-giant cell tumor of the salivary gland is an extremely rare tumor with distinct pathological features and unknown histogenesis. The neoplastic nature of these tumors in itself is questionable. We present the twentieth case in English literature of primary osteoclast like-giant cell tumor with accompanying low to intermediate grade salivary duct carcinoma of parotid gland, metastasizing to the ipsilateral cervical lymph node. As far as we know this is the second case with lymph node metastasis. Due to the rarity of the tumor its exact biological course is uncertain. We present and discuss this rare case with special emphasis on the histology, immunohistochemistry, and histogenesis.
authors.affiliation: Department of Histopathology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, Delhi, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Pasricha
authors.forename: Jatin S
authors.initials: JS
authors.lastname: Gandhi
authors.forename: Anurag
authors.initials: A
authors.lastname: Mehta
authors.forename: Gurudutt
authors.initials: G
authors.lastname: Gupta
authors.forename: Tapaswini
authors.initials: T
authors.lastname: Pradhan
mesh_terms: D044584:Carcinoma, Ductal / Q000175:diagnosis / Q000473:pathology*; D005870:Giant Cell Tumors / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D010010:Osteoclasts / Q000473:pathology*; D010306:Parotid Gland / Q000473:pathology*; D018987:Salivary Ducts / Q000473:pathology*; D012468:Salivary Gland Neoplasms / Q000175:diagnosis / Q000473:pathology*