title: Intracranial metastasis of neuroblastoma: in two different areas at the same time.
abstract: BACKGROUND
  Neuroblastoma (NB) is the most common extracranial solid malignancy in children. The major cause of death from this cancer is metastasis of tumors, and metastasis can be seen in different areas of the body. Metastasis of NB occurs by hematogenous and lymphatic routes. Generally, brain metastases have been reported in only one area of the brain parenchyma.
  
  
  METHODS
  A 4-year-old male patient was treated in our clinic due to the NB that settled in the intra-abdominal region, but the patient presented with headache and nausea approximately 5 months after completion of the treatment. Whereupon, cranial imaging was performed and two masses were detected in the bilateral frontal lobe, and then the patient underwent surgery. Metastatic NB diagnosis was confirmed histopathologically. The patient's chemotherapy treatment is still ongoing.
  
  
  CONCLUSIONS
  We report the case of a male patient with two separate metastatic masses in the brain parenchyma, which occurred in two different areas at the same time.
authors.affiliation: Faculty of Medicine, Department of Pediatric Hematology and Oncology, Selcuk University, Konya, Turkey, drdogankose@gmail.com.
authors.forename: Dogan
authors.initials: D
authors.lastname: Kose
authors.forename: Pinar
authors.initials: P
authors.lastname: Karabagli
authors.forename: Güler
authors.initials: G
authors.lastname: Yavas
authors.forename: Hakan
authors.initials: H
authors.lastname: Karabagli
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Koksal
mesh_terms: D000008:Abdominal Neoplasms / Q000473:pathology*; D001932:Brain Neoplasms / Q000556:secondary*; D002675:Child, Preschool; D006801:Humans; D008297:Male; D009447:Neuroblastoma / Q000556:secondary*