title: Auditory neuropathy spectrum disorder: predictive value of radiologic studies and electrophysiologic tests on cochlear implant outcomes and its radiologic classification.
abstract: CONCLUSIONS
  The width of the bony cochlear nerve canal (BCNC) and the size of the cochlear nerve are reliable predictors of long-term speech perception abilities for children with auditory neuropathy spectrum disorder (ANSD) after cochlear implantation (CI). In addition, electrical stapedial reflex (ESR) and electrical compound action potential (ECAP) also have considerable value in predicting postoperative speech perception abilities in these children.
  
  
  OBJECTIVE
  To assess whether speech perception abilities after CI in children with ANSD can be predicted from the results of radiologic studies and electrophysiologic tests.
  
  
  METHODS
  Fifteen children with ANSD underwent CI. The width of the BCNC and the size of the cochlear nerve were measured using preoperative CT and MRI. The results of early postoperative ESR, ECAP, and implant evoked electrical auditory brainstem response were reviewed. The latest speech perception test scores were also reviewed.
  
  
  RESULTS
  Radiologic findings of normal BCNC and normal cochlear nerve correlated with excellent speech perception abilities after CI. A narrow or obliterated BCNC and a deficient cochlear nerve correlated with poor speech perception abilities. Children with good speech perception abilities showed robust responses on ESR and ECAP, but there were no responses from any of the children with poor speech perception abilities.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Dong-A University, Busan, Korea.
authors.forename: Sung-Wook
authors.initials: SW
authors.lastname: Jeong
authors.forename: Lee-Suk
authors.initials: LS
authors.lastname: Kim
mesh_terms: D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation / Q000379:methods*; D003054:Cochlear Implants; D015331:Cohort Studies; D004594:Electrophysiology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006313:Hearing Loss, Central / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D011300:Preoperative Care / Q000379:methods; D012189:Retrospective Studies; D013067:Speech Perception / Q000502:physiology*; D014057:Tomography, X-Ray Computed / Q000145:classification / Q000379:methods; D016896:Treatment Outcome; D000160:Vestibulocochlear Nerve Diseases / Q000175:diagnosis / Q000601:surgery