title: UK Renal Registry 15th annual report: Chapter 6 haemoglobin, ferritin and erythropoietin amongst UK adult dialysis patients in 2011: national and centre-speciﬁc analyses.
abstract: BACKGROUND
  The UK Renal Association (RA) and National Institute for Health and Care Excellence (NICE) have published Clinical Practice Guidelines which include recommendations for management of anaemia in established renal failure.
  
  
  OBJECTIVE
  To determine the extent to which the guidelines for anaemia management are met in the UK.
  
  
  METHODS
  Quarterly data were obtained for haemoglobin (Hb) and factors that inﬂuence Hb from renal centres in England, Wales, Northern Ireland (E, W, NI) and the Scottish Renal Registry for the incident and prevalent renal replacement therapy (RRT) cohorts for 2011.
  
  
  RESULTS
  In the UK, in 2011 51% of patients commenced dialysis therapy with Hb ≥10.0 g/dl (median Hb 10 g/dl). Of patients in the early presentation group, 55% started dialysis with Hb ≥10.0 g/dl whilst 37% of patients presenting late started dialysis with Hb ≥10.0 g/dl. The UK median Hb of haemodialysis (HD) patients was 11.2 g/dl with an inter-quartile range (IQR) of 10.3-12.1 g/dl. Of UK HD patients, 82% had Hb ≥10.0 g/dl. The median Hb of peritoneal dialysis (PD) patients in the UK was 11.4 g/dl (IQR 10.5-12.3 g/dl). Of UK PD patients, 85% had Hb ≥10.0 g/dl. The median ferritin in HD patients in the UK was 436 mg/L (IQR 292-625) and 96% of HD patients had a ferritin ≥100 mg/ L. In EW&NI the median ferritin in PD patients was 273 mg/ L (IQR 153-446) with 86% of PD patients having a ferritin ≥100 mg/L. In EW&NI the mean erythropoietin stimulating agent (ESA) dose was higher for HD than PD patients (8,740 vs. 6,624 IU/week).
  
  
  CONCLUSIONS
  Prevalent HD and PD patients had 56% and 53% respectively within the Hb ≥10 and ≤12 g/dl target.
authors.affiliation: UK Renal Registry, Bristol, UK. renalregistry@renalregistry.nhs.uk
authors.forename: Anirudh
authors.initials: A
authors.lastname: Rao
authors.forename: Julie
authors.initials: J
authors.lastname: Gilg
authors.forename: Andrew
authors.initials: A
authors.lastname: Williams
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000847:Annual Reports as Topic; D015415:Biomarkers / Q000097:blood; D004921:Erythropoietin / Q000097:blood*; D005260:Female; D005293:Ferritins / Q000097:blood*; D006306:Health Surveys; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000453:epidemiology / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D009398:Nephrology / Q000706:statistics & numerical data / Q000639:trends; D015995:Prevalence; D012042:Registries; D006435:Renal Dialysis / Q000706:statistics & numerical data* / Q000639:trends; D012307:Risk Factors; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult
chemical_list: D015415:Biomarkers; D006454:Hemoglobins; D004921:Erythropoietin; D005293:Ferritins