title: Dynamics of electrocardiographic changes, brain-natriuretic peptide and cortisol levels in a patient with stress (takotsubo) cardiomyopathy--a case report.
abstract: BACKGROUND
  Takotsubo cardiomyopathy is a transient acute heart failure syndrome caused by stress that provokes left ventricular mid-apical akinesis and mimics acute coronary syndrome.
  
  
  METHODS
  A 66-year-old woman had chest pain and dispnoea a few hours before hospitalization. A sudden emotional stressful event preceded the symptoms. Electrocardiographic abnormalities--precordial ST elevation and modest increase of cardiac troponin mimiced acute myocardial infarction. However, echocardiographic examination showed apical ballooning with markedly diminished left ventricle ejection fraction and the obstruction in the outflow tract of the left ventricle. Coronary angiography at admission showed no coronary stenosis and slower blood flow through the left anterior descending artery. According to anamnesis, echocardiography and coronarography finding we established the diagnosis of stress cardiomyopathy--takotsubo cardiomyopathy. We described in details the slow but dynamic electrocardiographic changes, levels of brain natriuretic peptide, cortisol and echocardiography evolution of disease during a 4-month follow-up till the full recovery.
  
  
  CONCLUSIONS
  Stress (takotsubo) cardiomyopathy--became an important differential diagnosis of acute anterior myocardial infarction and it should be reconsidered every time when emotionally stressed patients with transient-apical akinesis or dyskinesis of the LV are present.
authors.affiliation: Clinic for Emergency Internal Medicine, Military Medical Academy, Belgrade, Serbia.
authors.forename: Ivica
authors.initials: I
authors.lastname: Djurić
authors.forename: Slobodan
authors.initials: S
authors.lastname: Obradović
authors.forename: Branko
authors.initials: B
authors.lastname: Gligić
mesh_terms: D000368:Aged; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D054549:Takotsubo Cardiomyopathy / Q000503:physiopathology*
chemical_list: D020097:Natriuretic Peptide, Brain; D006854:Hydrocortisone