title: Experience and acceptability of diets of varying protein content and glycemic index in an obese cohort: results from the Diogenes trial.
abstract: OBJECTIVE
  To investigate acceptability and tolerability of diets of different protein and glycemic index (GI) content aimed at weight maintenance following a phase of rapid weight loss, as part of a large pan-European dietary intervention trial.
  
  
  METHODS
  The Diogenes study (www.diogenes-eu.org) consisted of an initial 8-week rapid weight-loss phase (800-1000 kcal/day), followed by a 6-month weight maintenance intervention with five different diets varying in protein and GI content. Measurement of a range of outcomes relating to experience of the Diogenes diets in terms of acceptability, experience and mood were recorded via end of day questionnaires throughout the study.
  
  
  RESULTS
  Weight change during the initial weight loss phase weakly, but positively correlated with acceptability of the programme (r range=-0.08 to 0.2, P 0.05, n=685 on four of five dimensions). Success at weight maintenance positively correlated with acceptance of the programme (r range=-0.21 to -0.34, P<0.001, n=540 for all five dimensions). The diets with higher protein content were more acceptable than the low protein (LP) diets, however, no differences between the high vs low GI diets were found concerning acceptability and tolerability.
  
  
  CONCLUSIONS
  Results suggest that moderately high protein diets, compared with LP diets, are more acceptable diets for weight control in overweight individuals.
authors.affiliation: School Psychology, University of Surrey, Guildford, UK. aine.mcconnon@ucd.ie
authors.forename: A
authors.initials: A
authors.lastname: McConnon
authors.forename: G W
authors.initials: GW
authors.lastname: Horgan
authors.forename: C
authors.initials: C
authors.lastname: Lawton
authors.forename: J
authors.initials: J
authors.lastname: Stubbs
authors.forename: R
authors.initials: R
authors.lastname: Shepherd
authors.forename: A
authors.initials: A
authors.lastname: Astrup
authors.forename: T
authors.initials: T
authors.lastname: Handjieva-Darlenska
authors.forename: M
authors.initials: M
authors.lastname: Kunešová
authors.forename: T M
authors.initials: TM
authors.lastname: Larsen
authors.forename: A K
authors.initials: AK
authors.lastname: Lindroos
authors.forename: J A
authors.initials: JA
authors.lastname: Martinez
authors.forename: A
authors.initials: A
authors.lastname: Papadaki
authors.forename: A F H
authors.initials: AF
authors.lastname: Pfeiffer
authors.forename: M A
authors.initials: MA
authors.lastname: van Baak
authors.forename: M M
authors.initials: MM
authors.lastname: Raats
mesh_terms: D000328:Adult; D015992:Body Mass Index; D001835:Body Weight; D018753:Diet, Protein-Restricted; D004038:Diet, Reducing; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage; D005260:Female; D038321:Glycemic Index; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy*; D057240:Patient Preference; D015431:Weight Loss
chemical_list: D004040:Dietary Carbohydrates; D004044:Dietary Proteins