title: Autologous fat grafting: current state of the art and critical review.
abstract: BACKGROUND
  Despite the widespread use of autologous fat grafting in both reconstructive and cosmetic surgery, volume retention remains a significant problem. We aimed to critically appraise the current body of literature in fat grafting to provide a framework to guide application and comparison.
  
  
  METHODS
  Search of scientific databases and gray literature was conducted. Articles examining nonadipogenic applications of adipose tissue and those specific to breast reconstruction were excluded.
  
  
  RESULTS
  One hundred three articles were included. These fell under the headings of donor site, effect of infiltration solution, harvest method, effect of centrifugation, reinjection method, supplementation, the role of adipose-derived stem cells, and scaffolding.
  
  
  CONCLUSIONS
  Despite the significant research effort in this field, there remains no consensus as to the optimum technique. This stems from the vast array of research methods and short follow-up durations. Further, extrapolation of in vitro results to clinical settings has led to many conflicting practices.
authors.affiliation: From the *Taylor Laboratory, Department of Anatomy and Neurosciences, University of Melbourne; †Department of Plastic and Reconstructive Surgery, Royal Melbourne Hospital and University of Melbourne, Parkville; and ‡Australian Catholic University, Victoria Pde, Fitzroy, Victoria, Australia.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Ross
authors.forename: Ramin
authors.initials: R
authors.lastname: Shayan
authors.forename: Keith L
authors.initials: KL
authors.lastname: Mutimer
authors.forename: Mark W
authors.initials: MW
authors.lastname: Ashton
mesh_terms: D017667:Adipocytes; D000273:Adipose Tissue / Q000637:transplantation*; D006801:Humans; D014182:Transplantation, Autologous / Q000379:methods