title: Characteristics of chronic wounds that itch.
abstract: OBJECTIVE
  This study was designed to explore characteristics of chronic wounds that present with wound-related itch.
  
  
  BACKGROUND
  Although wound-related itch is recognized clinically, little is known about the phenomenon. Recent scientific advances have enabled the study of itch physiology, yet the clinical problem is not well described in the literature.
  
  
  METHODS
  The study was observational, descriptive.
  
  
  METHODS
  Persons (N = 200) with wounds being followed up at a hospital-affiliated wound care center were interviewed and assessed. Instruments included a health history tool, Paul-Pieper Itching Questionnaire, Bates-Jensen Wound Assessment Tool, and 10-g monofilament for assessment of sensation in the area of the wound.
  
  
  RESULTS
  Participants were aged 21 to 98 years (mean, 66.82 [SD, 14.02] years); 56% of the participants were men, and 85% were white. One-fourth (56/200) of the participants reported wound-related itch. Wounds that itched were generally larger (t77.74 = -3.27; P = .002; d = 0.63; 95% confidence interval [CI], -1.01 to -0.25), had more tissue edema (t88.38 = -2.19; P = .031; 95% CI, -0.93 to -0.47), and demonstrated more granulation tissue in the wound base (t98.71 = 2.03; P = .045; 95% CI, 0.01-0.87), compared with wounds without itch. Greater itch was associated with wounds that had a moderate amount of exudate (P = .02) or necrotic tissue in the base.
  
  
  CONCLUSIONS
  Wound itch was present in more severe wounds as evidenced by larger size, more tissue edema, and necrotic tissue. Understanding wound itch could promote wound healing and improve quality of life for persons with chronic wounds.
authors.affiliation: Plastic Surgery, William Beaumont Hospital, Royal Oak, MI, USA.
authors.forename: Julia
authors.initials: J
authors.lastname: Paul
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000553:Ambulatory Care; D002908:Chronic Disease; D015331:Cohort Studies; D016001:Confidence Intervals; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D011537:Pruritus / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D018570:Risk Assessment; D012720:Severity of Illness Index; D012737:Sex Factors; D017592:Skin Care / Q000379:methods; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology; D014947:Wounds and Injuries / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D055815:Young Adult