title: Trifluoromethylation reactions for the synthesis of β-trifluoromethylamines.
abstract: A multitalented system: N-migratory oxytrifluoromethylation and one-pot three-component reactions of allylamines as well as the aminotrifluoromethylation of alkenyl amines all proceeded efficiently in the presence of the Togni reagent (1) and CuI to afford a variety of β-trifluoromethylamine derivatives (see scheme).
authors.affiliation: Synthetic Organic Chemistry Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Egami
authors.forename: Shintaro
authors.initials: S
authors.lastname: Kawamura
authors.forename: Ayako
authors.initials: A
authors.lastname: Miyazaki
authors.forename: Mikiko
authors.initials: M
authors.lastname: Sodeoka
mesh_terms: D000499:Allylamine / Q000737:chemistry*; D000588:Amines / Q000138:chemical synthesis*; D002384:Catalysis; D003300:Copper; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis*; D007454:Iodides / Q000138:chemical synthesis*; D015394:Molecular Structure
chemical_list: D000588:Amines; D006845:Hydrocarbons, Fluorinated; D007454:Iodides; D000499:Allylamine; D003300:Copper; C073870:cuprous iodide
keywords: amines; aziridines; copper; multicomponent reactions; trifluoromethylation