title: Autoimmune polyglandular syndrome III in a patient with idiopathic portal hypertension.
abstract: A 42-year-old woman with a history of idiopathic portal hypertension (IPH) developed type 1A diabetes and was found to have chronic thyroiditis. The concurrence of IPH and type 1A diabetes has been previously reported in only one case. This is the second known case, and our patient was classified as having autoimmune polyglandular syndrome (APS) III. The patient's HLA DR and DQ alleles were determined to be susceptible to autoimmune thyroid diseases but resistant to type 1A diabetes.
authors.affiliation: Department of Diabetes and Endocrinology, Wakayama Medical Center Japanese Red Cross Society, Japan. yayayaya2221@gmail.com
authors.forename: Aya
authors.initials: A
authors.lastname: Iwahashi
authors.forename: Yasuki
authors.initials: Y
authors.lastname: Nakatani
authors.forename: Tomonao
authors.initials: T
authors.lastname: Hirobata
authors.forename: Hirosuke
authors.initials: H
authors.lastname: Nakata
authors.forename: Shogo
authors.initials: S
authors.lastname: Funakoshi
authors.forename: Yukitaka
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Gen
authors.initials: G
authors.lastname: Inoue
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000235:genetics / Q000276:immunology; D005260:Female; D006683:HLA-DQ Antigens / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications* / Q000235:genetics / Q000276:immunology; D008103:Liver Cirrhosis / Q000150:complications* / Q000235:genetics / Q000276:immunology; D010198:Pancytopenia / Q000150:complications* / Q000235:genetics / Q000276:immunology; D016884:Polyendocrinopathies, Autoimmune / Q000150:complications* / Q000235:genetics / Q000276:immunology; D013163:Splenomegaly / Q000150:complications* / Q000235:genetics / Q000276:immunology; D000094724:Idiopathic Noncirrhotic Portal Hypertension
chemical_list: D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens