title: Mycobacterium avium Complex-Associated Hemophagocytic Lymphohistiocytosis in a Sickle Cell Patient: An Unusual Fatal Association.
abstract: Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome, characterized clinically by fever, splenomegaly, cytopenia, and high ferritin. Infectious causes have been associated with secondary HLH, with viruses being the most common. We report a case of Mycobacterium avium complex-associated HLH in a sickle cell anemia patient. To the best of our knowledge, this association has never been reported in sickle cell anemia.
authors.affiliation: Department of Internal Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
authors.forename: Mohammed A R
authors.initials: MA
authors.lastname: Chamsi-Pasha
authors.forename: M Chadi
authors.initials: MC
authors.lastname: Alraies
authors.forename: Abdul Hamid
authors.initials: AH
authors.lastname: Alraiyes
authors.forename: Eric D
authors.initials: ED
authors.lastname: Hsi