title: Long-term test-retest reliability of the P3 NoGo wave and two independent components decomposed from the P3 NoGo wave in a visual Go/NoGo task.
abstract: The objective of the current study was to determine long-term test-retest reliability of the P3 NoGo wave as well as two independent components (IC P3 NoGo early and IC P3 NoGo late) decomposed from this wave by independent component analysis (ICA). For this purpose 19-channel EEG was recorded during a cued visual Go/NoGo task. First, spatial filters of the two independent components (ICs) were obtained by application of ICA to ERPs of 102 healthy adults. Second, in 26 individuals, ERPs were recorded from the same task a second time 6-18 months after the first recording. Statistical analyses were performed on both the P3 NoGo waves and the activation curves of the two ICs from both recordings. Amplitude and latency were estimated by "peak" and "fractional area" (FA) methods for both the P3 NoGo wave and ICs. Intraclass correlations (ICC) for latency were excellent (ICC>.90) for both the P3 NoGo wave and the two ICs when measured with the FA method, and good (ICC>.75) for amplitude measured by both methods (FA or peak). We conclude that the long-term stability of P3 NoGo wave and the two IC makes them well suited for reliable assessment of cognitive control function in research and clinic.
authors.affiliation: Department of Physical medicine and rehabilitation, St.Olav Hospital, Trondheim University Hospital, Norway; Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway. jan.brunner@stolav.no
authors.forename: Jan Ferenc
authors.initials: JF
authors.lastname: Brunner
authors.forename: Tor Ivar
authors.initials: TI
authors.lastname: Hansen
authors.forename: Alexander
authors.initials: A
authors.lastname: Olsen
authors.forename: Toril
authors.initials: T
authors.lastname: Skandsen
authors.forename: Asta
authors.initials: A
authors.lastname: Håberg
authors.forename: Juri
authors.initials: J
authors.lastname: Kropotov
mesh_terms: D000328:Adult; D016477:Artifacts; D001767:Blinking; D003463:Cues; D003627:Data Interpretation, Statistical; D004569:Electroencephalography; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation; D025341:Principal Component Analysis; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D015203:Reproducibility of Results; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult
keywords: ERP; Independent component analysis; P3 NoGo; Reliability