title: Social and functional capacity of schizophrenia patients: A cross-sectional study.
abstract: BACKGROUND
  The chronic course of schizophrenia typically results in severe social, vocational and functional impairment, interferes with patients' autonomy, reduces quality of life and increases disability.
  
  
  OBJECTIVE
  The aim of our study was: (1) to assess social and functional impairment in schizophrenia outpatients from the Czech Republic and Slovakia; and (2) to examine a relationship between functioning and antipsychotic treatment and demographic variables.
  
  
  METHODS
  Schizophrenia outpatients in a stable phase of illness, treated with current antipsychotic medication for a minimum of one month, were enrolled for the study. Demographic and medication data were recorded. The Personal and Social Performance (PSP), Subjective Well-Being under Neuroleptics (SWN) and Clinical Global Impressions (CGI) scales were administered.
  
  
  RESULTS
  The total number of study subjects was 926. Most PSP values were within the interval of moderate impairment. Functional performance correlated positively with subjective satisfaction with medication and negatively with symptom severity. Higher education predicted better functioning on PSP. The best performance was associated with a stable relationship and a useful work role. Patients who showed the best level of functioning were more likely to be treated with antipsychotic monotherapy. No difference among drugs in monotherapy was found in subjective satisfaction.
  
  
  CONCLUSIONS
  The PSP values of stable schizophrenia outpatients indicated a moderate degree of impairment. Improvement of functional capacity remains one of the unmet needs of schizophrenia patients.
authors.affiliation: Prague Psychiatric Centre, Czech Republic, 3rd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic mohr@pcp.lf3.cuni.cz.
authors.forename: Pavel
authors.initials: P
authors.lastname: Mohr
authors.affiliation: Prague Psychiatric Centre, Prague, Czech Republic.
authors.forename: Mabel
authors.initials: M
authors.lastname: Rodriguez
authors.affiliation: Prague Psychiatric Centre, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
authors.forename: Anna
authors.initials: A
authors.lastname: Bravermanová
authors.affiliation: Prague Psychiatric Centre, Czech Republic, 3rd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
authors.forename: Tomáš
authors.initials: T
authors.lastname: Melicher
authors.affiliation: Prague Psychiatric Centre, Prague, Czech Republic.
authors.forename: Zuzana
authors.initials: Z
authors.lastname: Čeplová
authors.affiliation: Prague Psychiatric Centre, Czech Republic, 3rd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
authors.forename: Jan
authors.initials: J
authors.lastname: Čermák
authors.affiliation: Psychiatric Clinic, University Hospital Bratislava, Slovakia, Faculty of Medicine, Comenius University in Bratislava, Bratislava, Slovakia.
authors.forename: Ján
authors.initials: J
authors.lastname: Pečeňák
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010549:Personal Satisfaction; D012559:Schizophrenia / Q000188:drug therapy / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D012720:Severity of Illness Index; D018154:Slovakia
chemical_list: D014150:Antipsychotic Agents
keywords: Schizophrenia; antipsychotic drugs; functional outcome; patient outcome assessment; well-being