title: Strongyloides stercoralis infection in an intestinal transplant recipient.
abstract: Strongyloides stercoralis is a helminth in tropical and subtropical areas. It may cause latent infection and progress to Strongyloides hyperinfection syndrome, which is associated with a high mortality rate. Transplant recipients under the treatment of immunosuppressant agents are at risk of severe S. stercoralis infection. According to related literature, most cases of S. stercoralis infection after solid organ transplantation are caused by reactivation of latent infections in the recipients, whereas only a few are acquired from the donors. We report on an intestinal transplant recipient who had S. stercoralis infection diagnosed by a larva of this parasite found in the stool from the ileostomy stoma 1 month after transplantation. The donor was considered the source of the infection because the donor was from an endemic area and had marked eosinophilia, and the recipient had no contact history or clinical manifestations related to the S. stercoralis infection before transplantation. The patient was treated with ivermectin and exhibited no evidence of infection after 7 months.
authors.affiliation: Division of Pediatric Surgery, Department of Surgery, Far Eastern Memorial Hospital, Pan-Chiao, New Taipei, Taiwan.
authors.forename: C N
authors.initials: CN
authors.lastname: Hsu
authors.forename: S H
authors.initials: SH
authors.lastname: Tseng
authors.forename: S W
authors.initials: SW
authors.lastname: Chang
authors.forename: Y
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007422:Intestines / Q000469:parasitology / Q000637:transplantation*; D007559:Ivermectin / Q000627:therapeutic use; D016377:Organ Transplantation / Q000009:adverse effects*; D017171:Strongyloides stercoralis / Q000302:isolation & purification*; D013322:Strongyloidiasis / Q000175:diagnosis* / Q000469:parasitology / Q000635:transmission; D014019:Tissue Donors
chemical_list: D000871:Anthelmintics; D007559:Ivermectin
keywords: Strongyloides stercoralis; donor-derived infection; intestinal transplantation