title: Smart three-dimensional gas chromatography.
abstract: We developed a complete computer-controlled smart 3-dimensional gas chromatography (3-D GC) system with an automation algorithm. This smart 3-D GC architecture enabled independent optimization of and control over each dimension of separation and allowed for much longer separation time for the second- and third-dimensional columns than the conventional comprehensive 3-D GC could normally achieve. Therefore, it can potentially be employed to construct a novel GC system that exploits the multidimensional separation capability to a greater extent. In this Article, we introduced the smart 3-D GC concept, described its operation, and demonstrated its feasibility by separating 22 vapor analytes.
authors.affiliation: Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States.
authors.forename: Di
authors.initials: D
authors.lastname: Chen
authors.forename: Jung Hwan
authors.initials: JH
authors.lastname: Seo
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.forename: Katsuo
authors.initials: K
authors.lastname: Kurabayashi
authors.forename: Xudong
authors.initials: X
authors.lastname: Fan
mesh_terms: D002849:Chromatography, Gas / Q000295:instrumentation / Q000379:methods*; D017076:Computer-Aided Design; D004867:Equipment Design / Q000295:instrumentation / Q000379:methods*