title: Real-Time Monitoring of Pseudomonas Aeruginosa Concentration Using a Novel Electromagnetic Sensors Microfluidic Cell Structure.
abstract: This study demonstrates an electromagnetic wave-based sensor embedded within a fluidic cell for the purposes of quantifying Pseudomonas aeruginosa in real time, which implies it could be applied for provision of point-of-care diagnostics. The sensors operates through the interaction of the electromagnetic field with the analyte flowing through the fluidic system, and via the sensor head which has a specifically designed planar pattern to maximize the sensor sensitivity for the given bacteria type. The sensor is demonstrated to respond linearly (R(2) = 0.9942) to OD(550) 25 × 10(-3) - 1.0 bacteria concentration through changing resonant frequency and peak quality factor. This innovative approach is expected to contribute to better provision of healthcare services, minimizing the need for hospital visits through real-time point-of-care diagnostics as opposed to lengthy laboratory assays.
authors.forename: Richard
authors.initials: R
authors.lastname: Blakey
authors.forename: Ismini
authors.initials: I
authors.lastname: Nakouti
authors.forename: Olga
authors.initials: O
authors.lastname: Korostynska
authors.forename: Alex
authors.initials: A
authors.lastname: Mason
authors.forename: Ahmed
authors.initials: A
authors.lastname: Al-Shamma'a
mesh_terms: D001431:Bacteriological Techniques / Q000295:instrumentation* / Q000379:methods*; D015374:Biosensing Techniques / Q000295:instrumentation*; D004574:Electromagnetic Fields; D004867:Equipment Design; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D019095:Point-of-Care Systems; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification* / Q000502:physiology