title: Race/ethnicity disparities in dysglycemia among U.S. women of childbearing age found mainly in the nonoverweight/nonobese.
abstract: OBJECTIVE
  To describe the burden of dysglycemia-abnormal glucose metabolism indicative of diabetes or high risk for diabetes-among U.S. women of childbearing age, focusing on differences by race/ethnicity.
  
  
  METHODS
  Using U.S. National Health and Nutrition Examination Survey data (1999-2008), we calculated the burden of dysglycemia (i.e., prediabetes or diabetes from measures of fasting glucose, A1C, and self-report) in nonpregnant women of childbearing age (15-49 years) by race/ethnicity status. We estimated prevalence risk ratios (PRRs) for dysglycemia in subpopulations stratified by BMI (measured as kilograms divided by the square of height in meters), using predicted marginal estimates and adjusting for age, waist circumference, C-reactive protein, and socioeconomic factors.
  
  
  RESULTS
  Based on data from 7,162 nonpregnant women, representing>59,000,000 women nationwide, 19% (95% CI 17.2-20.9) had some level of dysglycemia, with higher crude prevalence among non-Hispanic blacks and Mexican Americans vs. non-Hispanic whites (26.3% [95% CI 22.3-30.8] and 23.8% [19.5-28.7] vs. 16.8% [14.4-19.6], respectively). In women with BMI<25 kg/m2, dysglycemia prevalence was roughly twice as high in both non-Hispanic blacks and Mexican Americans vs. non-Hispanic whites. This relative increase persisted in adjusted models (PRRadj 1.86 [1.16-2.98] and 2.23 [1.38-3.60] for non-Hispanic blacks and Mexican Americans, respectively). For women with BMI 25-29.99 kg/m2, only non-Hispanic blacks showed increased prevalence vs. non-Hispanic whites (PRRadj 1.55 [1.03-2.34] and 1.28 [0.73-2.26] for non-Hispanic blacks and Mexican Americans, respectively). In women with BMI>30 kg/m2, there was no significant increase in prevalence of dysglycemia by race/ethnicity category.
  
  
  CONCLUSIONS
  Our findings show that dysglycemia affects a significant portion of U.S. women of childbearing age and that disparities by race/ethnicity are most prominent in the nonoverweight/nonobese.
authors.affiliation: Corresponding author: Jessica A. Marcinkevage, jmarcinkevage@cdc.gov.
authors.forename: Jessica A
authors.initials: JA
authors.lastname: Marcinkevage
authors.forename: C J
authors.initials: CJ
authors.lastname: Alverson
authors.forename: K M Venkat
authors.initials: KM
authors.lastname: Narayan
authors.forename: Henry S
authors.initials: HS
authors.lastname: Kahn
authors.forename: Julia
authors.initials: J
authors.lastname: Ruben
authors.forename: Adolfo
authors.initials: A
authors.lastname: Correa
mesh_terms: D000293:Adolescent; D000328:Adult; D001741:Black or African American; D000367:Age Factors; D044383:Black People; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight / Q000502:physiology; D002097:C-Reactive Protein / Q000378:metabolism; D003920:Diabetes Mellitus / Q000097:blood* / Q000208:ethnology* / Q000378:metabolism; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D008875:Middle Aged; D011236:Prediabetic State / Q000097:blood* / Q000208:ethnology* / Q000378:metabolism; D012959:Socioeconomic Factors; D014481:United States; D055105:Waist Circumference / Q000502:physiology; D044465:White People; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D002097:C-Reactive Protein