title: Small cell variant of anaplastic large cell lymphoma presenting as arm mass in a child: a rare entity with diagnostic challenge.
abstract: Anaplastic lymphoma kinase positive, anaplastic large cell lymphoma (ALCL) is an uncommon T-cell non-Hodgkin lymphoma. A rare morphological variant-small cell variant of ALCL may pose diagnostic challenge especially when it presents primarily as a soft tissue mass. We present a rare case of small cell variant of ALCL in a 14-year-old female presented with arm swelling with emphasis on clinical, morphological and immunohistochemical aspects. Pathologists should be aware of this entity when considering a differential diagnosis of malignant round cell tumor as early and correct diagnosis has important clinical implications.
authors.affiliation: Department of Pathology. Rajiv -Gandhi Cancer -Institute & Research Centre, Sector 5, -Rohini, New Delhi, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Pasricha
authors.forename: Jatin S
authors.initials: JS
authors.lastname: Gandhi
authors.forename: Gurudutt
authors.initials: G
authors.lastname: Gupta
authors.forename: Anurag
authors.initials: A
authors.lastname: Mehta
mesh_terms: D000293:Adolescent; D000077548:Anaplastic Lymphoma Kinase; D001132:Arm / Q000473:pathology*; D005260:Female; D006801:Humans; D017728:Lymphoma, Large-Cell, Anaplastic / Q000175:diagnosis* / Q000201:enzymology / Q000378:metabolism / Q000473:pathology*; D020794:Receptor Protein-Tyrosine Kinases / Q000378:metabolism
chemical_list: C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases