title: One-pot one-step deracemization of amines using ω-transaminases.
abstract: In this study, we developed a one-pot one-step deracemization method for the production of various enantiomerically pure amines using two opposite enantioselective ω-TAs. Using this method, various aromatic amines were successfully converted to their (R)-forms (>99%) with good conversion.
authors.affiliation: School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, South Korea. hyungdon@ynu.ac.kr.
authors.forename: Giyoung
authors.initials: G
authors.lastname: Shin
authors.forename: Sam
authors.initials: S
authors.lastname: Mathew
authors.forename: Minsu
authors.initials: M
authors.lastname: Shon
authors.forename: Byung-Gee
authors.initials: BG
authors.lastname: Kim
authors.forename: Hyungdon
authors.initials: H
authors.lastname: Yun
mesh_terms: D001419:Bacteria / Q000201:enzymology*; D042621:Comamonadaceae / Q000201:enzymology; D009161:Mycobacterium / Q000201:enzymology; D055326:Neosartorya / Q000201:enzymology*; D010627:Phenethylamines / Q000737:chemistry* / Q000378:metabolism*; D013237:Stereoisomerism; D000637:Transaminases / Q000378:metabolism*; D014733:Vibrio / Q000201:enzymology
chemical_list: D010627:Phenethylamines; D000637:Transaminases; C033198:1-phenethylamine