title: The impact of the Benign Brain Tumor Cancer Registries Amendment Act (Public Law 107-260) on non-malignant brain and central nervous system tumor incidence trends.
abstract: The study objective was to investigate patterns of reported non-malignant brain and CNS tumor incidence over a time period encompassing 1997-2008 during which time the Benign Brain Tumor Cancer Registries Amendment Act (PL 107-260) was passed and implemented. Analyses of 75,350 incident non-malignant brain and CNS tumors from eleven population-based central registries revealed that there were statistically significant increases in the age-adjusted incidence rate for non-malignant tumors for those diagnosed prior to 2002 and over the time period from 2002 until 2005. However, no significant change in the age-adjusted incidence rate for non-malignant tumors was observed over the time period 2005 to 2008 indicating that the incidence from this time period may quantify the "true" incidence of non-malignant brain and CNS tumors in the United States.
authors.forename: Bridget J
authors.initials: BJ
authors.lastname: McCarthy
authors.forename: Carol
authors.initials: C
authors.lastname: Kruchko
authors.forename: Therese A
authors.initials: TA
authors.lastname: Dolecek
mesh_terms: D001932:Brain Neoplasms / Q000453:epidemiology / Q000473:pathology; D016543:Central Nervous System Neoplasms / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D019221:Mandatory Reporting; D012042:Registries / Q000706:statistics & numerical data*; D017678:Sex Distribution; D013997:Time Factors; D014481:United States / Q000453:epidemiology