title: Comparison of diagnostic accuracy of Doppler USG and contrast-enhanced magnetic resonance angiography and selective renal arteriography in patients with atherosclerotic renal artery stenosis.
abstract: BACKGROUND
  There are many systemic complications of conventional selective renal arteriography (SRA), such as contrast-mediated nephropathy. Contrast-enhanced magnetic resonance angiography (CE-MRA) and renal artery Doppler ultrasonography (DUSG) have been used increasingly for renal artery stenosis (RAS). The aim of this study was to evaluate the accuracy of CE-MRA and DUSG as used for diagnosis of RAS.
  
  
  METHODS
  We divided 130 consecutive patients investigated for resistant hypertension into 2 groups based on age: group 1 was patients <60 years old and group 2 was patients >60 year. DUSG, CE-MRA, and SRA were performed in group 1 and group 2 patients.
  
  
  RESULTS
  Seventy-two patients (24 males [M], 48 females [F]) in group 1, and 58 patients (26 M, 32 F) in group 2 were included in the study. In the evaluation of clinically significant renal artery stenosis with DUSG, in group 1 the overall sensitivity was 83.33% and overall specificity was 81.82%, and in group 2 they were 69.23% and 0%, respectively, when compared with SRA. In the evaluation of clinically significant renal artery stenosis with CE-MRA, the overall sensitivity and specificity were 92.31% and 36.36%, respectively, in group 1 and 100.00% and 73.33%, respectively in group 2, when compared with SRA.
  
  
  CONCLUSIONS
  CE-MRA is an accurate, non-invasive method for the diagnosis of RAS in patients above 60 years of age and DUSG may be the choice of diagnostic method for RAS in patients under 60 years of age.
authors.affiliation: Department of Internal Medicine, Division of Nephrology, School of Medicine, Mersin University, Mersin, Turkey. k.turgutalp@hotmail.com
authors.forename: Kenan
authors.initials: K
authors.lastname: Turgutalp
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kiykim
authors.forename: Onur
authors.initials: O
authors.lastname: Özhan
authors.forename: Ilter
authors.initials: I
authors.lastname: Helvaci
authors.forename: Türkay
authors.initials: T
authors.lastname: Ozcan
authors.forename: Altan
authors.initials: A
authors.lastname: Yildiz
mesh_terms: D000328:Adult; D000792:Angiography; D050197:Atherosclerosis / Q000000981:diagnostic imaging*; D003287:Contrast Media; D003710:Demography; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D012077:Renal Artery / Q000000981:diagnostic imaging*; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D018608:Ultrasonography, Doppler
chemical_list: D003287:Contrast Media