title: Long-term visual and ocular health outcomes of 2 sets of bilaterally aphakic siblings utilizing contact lens correction.
abstract: We report the long-term clinical courses of 8 aphakic eyes of 2 sets of siblings who used contact lenses for both refractive correction and amblyopia treatment following neonatal cataract extraction. Early cataract removal, aggressive contact lens use, and robust professional supervision seem to have substantially contributed to visual success in our four patients. All eyes did well visually with contact lenses, all developing acuities close to 20/20 despite contact lens and non-contact lens related complications that were managed. Complications of most concern were corneal neovascularization and glaucoma. We believe this to be the first case series documenting consistent long-term visual and ocular health outcomes of sets of bilaterally aphakic siblings optically treated with contact lenses.
authors.affiliation: Jules Stein Eye Institute and Department of Ophthalmology, David Geffen School of Medicine at UCLA, 100 Stein Plaza, Los Angeles, CA 90004, USA. mhwoo@ucla.edu
authors.forename: Minhee
authors.initials: M
authors.lastname: Woo
authors.forename: Sherwin
authors.initials: S
authors.lastname: Isenberg
authors.forename: Sharon N
authors.initials: SN
authors.lastname: Spooner
authors.forename: Barry A
authors.initials: BA
authors.lastname: Weissman
mesh_terms: D000550:Amblyopia / Q000175:diagnosis* / Q000209:etiology / Q000534:rehabilitation*; D001035:Aphakia / Q000150:complications / Q000175:diagnosis* / Q000534:rehabilitation*; D003261:Contact Lenses; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008137:Longitudinal Studies; D008297:Male; D016896:Treatment Outcome