title: A parallelism between spectral grading and Gleason grading of malignant prostate tissues.
abstract: Gleason score is the most common method of grading the virulence of prostate malignancy and is based on the pathological assessment of morphology of cellular matrix. Since this involves the excision of the tissue, we are working on a new, minimally invasive, non-contact, procedure of spectral diagnosis of prostate malignancy. In this preliminary in vitro study reported here, we have analyzed 27 tissue samples (normal control=7: benign=8: malignant=12) by Stokes' shift spectra (SSS) to establish a one-to-one correspondence between spectral grading and Gleason grading.
authors.affiliation: Research Chair on Laser Diagnosis of Cancers, King Saud University, Riyadh, Saudi Arabia.
authors.forename: V
authors.initials: V
authors.lastname: Masilamani
authors.forename: M S
authors.initials: MS
authors.lastname: Alsalhi
authors.forename: S
authors.initials: S
authors.lastname: Devanesan
authors.forename: M
authors.initials: M
authors.lastname: Atif
authors.forename: D
authors.initials: D
authors.lastname: Rabah
authors.forename: K
authors.initials: K
authors.lastname: Farhat
authors.forename: Y
authors.initials: Y
authors.lastname: Pu
authors.forename: R R
authors.initials: RR
authors.lastname: Alfano
mesh_terms: D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D006801:Humans; D008297:Male; D060787:Neoplasm Grading; D011471:Prostatic Neoplasms / Q000473:pathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013050:Spectrometry, Fluorescence / Q000379:methods*