title: ICl-induced intramolecular electrophilic cyclization of 1-[4'-methoxy(1,1'-biphenyl)2-yl]alkynones--a facile approach to spiroconjugated molecules.
abstract: Spiro compounds: An iodine monochloride-induced intramolecular cyclization of 1-[4'-methoxy(1,1'-biphenyl)2-yl]alkynones has been developed (see scheme). An electrophilic iodocyclization selectively takes place at the ipso position (versus the ortho electrophilic aromatic substitution) to afford 4'H-spiro(cyclohexa[2,5]diene-1,1'-naphthalene)-4,4'-diones, a new group of spiroconjugated compounds.
authors.affiliation: Department of Chemistry and Biochemistry, Queens College and the Graduate Center of the City University of New York, 65-30 Kissena Blvd. Flushing, New York 11367, USA. yu.chen1@qc.cuny.edu
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
authors.forename: Xiaochen
authors.initials: X
authors.lastname: Liu
authors.forename: Minwook
authors.initials: M
authors.lastname: Lee
authors.forename: Chenlong
authors.initials: C
authors.lastname: Huang
authors.forename: Igor
authors.initials: I
authors.lastname: Inoyatov
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Chen
authors.forename: Abraham C
authors.initials: AC
authors.lastname: Perl
authors.forename: William H
authors.initials: WH
authors.lastname: Hersh
keywords: cyclization; electrophilic addition/substitution; iodine monochloride; spiro compounds; substituent effects