title: [Neurological disorders related to vitamin B12 deficiency in prisons in Guinea: a 22-case study].
abstract: Neurological disorders related to vitamin B12 deficiency are common in prisons of tropical Africa. We collected 22 cases (20 men and 2 women). They all showed vitamin B12 deficiency associated with neurological signs that were represented by sclerosis combined with bone marrow (n = 9), peripheral neuropathy (n = 6), cerebellar syndrome (n = 2), a pyramidal syndrome of the lower limbs (n = 4) and optic neuropathy (n = 1). Laboratory tests showed a mean hemoglobin concentration of 7.2 ± 1.5 g/dl, mean 104 ± 28 fl, macrocytic anemia in 10 patients. Biermer's disease was identified in 9 patients, 3 patients showed the syndrome of non dissociation of vitamin B12, a gastrectomy in 2 patients and no etiology was identified in 8 patients.
authors.affiliation: Service de neurologie, CHU Conakry, Conakry, République de Guinée.
authors.forename: F A
authors.initials: FA
authors.lastname: Cisse
authors.forename: H
authors.initials: H
authors.lastname: Bah
authors.forename: F
authors.initials: F
authors.lastname: Konate
authors.forename: N
authors.initials: N
authors.lastname: Camara
authors.forename: M I
authors.initials: MI
authors.lastname: Camara
authors.forename: K
authors.initials: K
authors.lastname: Conde
authors.forename: I F B
authors.initials: IF
authors.lastname: Kassory
authors.forename: A
authors.initials: A
authors.lastname: Sanogo
authors.forename: I
authors.initials: I
authors.lastname: Diakhate
authors.forename: A
authors.initials: A
authors.lastname: Cisse
mesh_terms: D000328:Adult; D015331:Cohort Studies; D004576:Electromyography; D005260:Female; D016701:Guinea; D006801:Humans; D006879:Hydroxocobalamin / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011330:Prisons; D014806:Vitamin B 12 Deficiency / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D006879:Hydroxocobalamin