title: [Frequency of detection of different hepatitis C virus subtypes in the Moscow region].
abstract: There is a high degree of the hepatitis C virus (HCV) infection in Moscow region. The analysis of different HCV subtypes is caused by the necessity of prognostic estimation of predominant subtypes for the near future because new schemes of antiviral therapy for several HCV genotypes are developed. It is established that subtype 1b (52.1%) prevails in Moscow region. The increase of subtype 3a (37.2%) against the decrease in subtype 1b is observed. In patients infected before 1990 HCV subtype 1b is predominant and liver cirrhosis is detected in 46.7% of cases. The intergenotypic recombinant 2k/1b is registered with the frequency of 0.8% and about 2% of cases of mixed HCV subtypes are detected.
authors.forename: E I
authors.initials: EI
authors.lastname: Samokhvalov
authors.forename: L I
authors.initials: LI
authors.lastname: Nikolaeva
authors.forename: S V
authors.initials: SV
authors.lastname: Al'khovskiĭ
authors.forename: V V
authors.initials: VV
authors.lastname: Khlopova
authors.forename: E V
authors.initials: EV
authors.lastname: Petrova
authors.forename: G V
authors.initials: GV
authors.lastname: Sapronov
authors.forename: N M
authors.initials: NM
authors.lastname: Beliaeva
authors.forename: D K
authors.initials: DK
authors.lastname: L'vov
mesh_terms: D000328:Adult; D005260:Female; D005838:Genotype; D016174:Hepacivirus / Q000235:genetics*; D006526:Hepatitis C / Q000188:drug therapy / Q000453:epidemiology / Q000235:genetics*; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012426:Russia / Q000453:epidemiology