title: Symptomatic hypocalcaemia secondary to PTH resistance associated with hypomagnesaemia after elective embolisation of uterine fibroid.
abstract: Four weeks after elective embolisation of a symptomatic benign uterine fibroid, a lady presented to her general practitioner with facial twitching and severe lassitude. Acute hypocalcaemia was diagnosed. Further investigations demonstrated hypomagnesaemia. Parathyroid hormone (PTH) was within normal limits. Symptoms and the acute metabolic disturbance resolved with treatment by oral magnesium and calcium supplementation. While lassitude is a common symptom of postfibroid embolisation and may last for up to 6 weeks, the presentation with facial twitching alerted the clinician to a potential electrolyte or metabolic imbalance. This is a first reported case of hypomagnesaemia associated with PTH resistance leading to hypocalcaemia precipitated by alcohol particle embolisation for benign fibroid disease.
authors.affiliation: Department of Endocrinology, South Infirmary Victoria University Hospital, Cork, Ireland.
authors.forename: Tomas Patrick
authors.initials: TP
authors.lastname: Griffin
authors.forename: Michael
authors.initials: M
authors.lastname: Murphy
authors.forename: John
authors.initials: J
authors.lastname: Coulter
authors.forename: Matthew Stjohn
authors.initials: MS
authors.lastname: Murphy
mesh_terms: D004621:Embolization, Therapeutic; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology*; D007889:Leiomyoma / Q000628:therapy*; D008275:Magnesium Deficiency / Q000150:complications*; D010281:Parathyroid Hormone / Q000502:physiology*
chemical_list: D010281:Parathyroid Hormone