title: [Adaptive changes of Zebrafish (Danio rerio) to anaerobic exercise training].
abstract: To explore adaptive changes of the Zebrafish (Danio rerio) to anaerobic exercise training as well as to collect basic data of molecular mechanisms of adaption to anaerobic exercise training among this fish, we investigated the influences of 4 weeks of anaerobic exercise training on the behavior, morphology, growth, muscle biochemical components and metabolic enzyme activities of the Zebrafish. Our results indicated that individual's daily activity level declined after 4 weeks training and they preferred to swim together more frequently. Both body length and weight gain decreased, allowing the fish to adapt to the increased locomotion. Similarly, glycogen in muscles increased and exercise endurance also strengthened due to the enhancement of energy storage. Moreover, although the activity of lactate dehydrogenase (LDH) in muscle has increased, the activity of citrate synthase (CS) decreased. Taken together, these results suggest that both the ability of anaerobic exercise and anaerobic metabolism of Zebrafish can in fact be enhanced by training, and the tangible changes that we could measure were retained, but only for a limited time.
authors.affiliation: Chongqing Key Laboratory of Translational Medical Research in Cognitive Development and Learning and Memory Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. wangzj1969@126.com, wangzj@swu.edu.cn.
authors.forename: Ming-jing
authors.initials: MJ
authors.lastname: Liu
authors.forename: Zhi-jian
authors.initials: ZJ
authors.lastname: Wang
mesh_terms: D000818:Animals; D002950:Citrate (si)-Synthase / Q000378:metabolism; D029941:Fish Proteins / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008124:Locomotion; D018482:Muscle, Skeletal / Q000201:enzymology / Q000502:physiology; D010805:Physical Conditioning, Animal; D013550:Swimming; D015027:Zebrafish / Q000254:growth & development / Q000502:physiology*
chemical_list: D029941:Fish Proteins; D007770:L-Lactate Dehydrogenase; D002950:Citrate (si)-Synthase
keywords: Adaption; Anaerobic exercise training; Enzyme; Morphology; Zebrafish (Danio rerio)