title: [Bilateral internal carotid artery occlusion and severe basilar artery stenosis in a patient with fibromuscular dysplasia: a case report].
abstract: Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory arterial disease of unknown etiology. We report a 26-year-old woman who presented with transient ischemic attack (TIA) due to bilateral internal carotid artery (ICA) occlusion and severe basilar artery stenosis, as FMD was diagnosed by a biopsy specimen of right ICA. Imaging investigations included magnetic resonance angiography and catheter angiogram without characteristic "string of beads" pattern, before reaching a definitive diagnosis by pathologist. Anti-platelet therapy and bypass surgery of superficial temporal artery-middle cerebral artery revealed no more clinical symptoms. This case of intra- and extra-cranial FMD gives a consideration of such rare disease in the differential diagnosis of TIA or stroke in healthy young patients. The literature of FMD is reviewed including pathological findings.
authors.affiliation: Department of Neurology, Social Insurance Chukyo Hospital.
authors.forename: Shunichi
authors.initials: S
authors.lastname: Yoshida
authors.forename: Kaoru
authors.initials: K
authors.lastname: Eguchi
authors.forename: Kazunari
authors.initials: K
authors.lastname: Onodera
authors.forename: Kengo
authors.initials: K
authors.lastname: Suzuki
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Fujishiro
authors.forename: Shigeo
authors.initials: S
authors.lastname: Riku
mesh_terms: D000328:Adult; D016893:Carotid Stenosis / Q000209:etiology*; D005260:Female; D005352:Fibromuscular Dysplasia / Q000150:complications*; D006801:Humans; D014715:Vertebrobasilar Insufficiency / Q000209:etiology*