title: [Determination of volatile N-nitrosamine compounds in salted aquatic products by gas chromatography-mass spectrometry].
abstract: An analytical method was developed for the determination of the extraction of volatile N-nitrosamine compounds including N-nitrosodimethylamine ( NDMA) , N-nitrosodiethylamine (NDEA), N-nitrosodipropylamine (NDPA), N-nitrosodibutylamine (NDBA), N-nitrosopiperidine (NPIP), and N-nitrosopyrrolidine (NPYR) from salted aquatic products by gas chromatography-mass spectrometry (GC-MS). In this experiment, the separation and detection conditions were optimized for different extraction methods, solid-phase extraction columns, and chromatographic columns. The results showed that the linear correlation coefficients (R2) were higher than 0. 999 8 within 10 - 1 000 micro g/L, and the reproducibilities were good with the - relative standard deviations (RSD) less than 8%. The recoveries were 79% - 105%. It is noted that this method for the determination of volatile N-nitrosamine compounds in salted aquatic products was much more sensitivity and with a lower detection limits (0. 05 micro g/kg except NDPA) than the previously reported methods. This proposed method is rapid and convenient for the determination, and easy for the operation. It is appropriate for the determination of volatile N-nitrosamine compounds in various salted aquatic products.
authors.affiliation: National Marine Food Quality Supervision and Testing Center, Zhoushan 316021, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhao
authors.forename: Xiuyuan
authors.initials: X
authors.lastname: Wang
authors.forename: Pingya
authors.initials: P
authors.lastname: Wang
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhou
authors.forename: Chaobo
authors.initials: C
authors.lastname: Xue
authors.forename: Lingbo
authors.initials: L
authors.lastname: Jiang
mesh_terms: D000818:Animals; D059001:Aquatic Organisms; D005396:Fish Products / Q000032:analysis*; D005504:Food Analysis / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D005519:Food Preservation / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D009602:Nitrosamines / Q000032:analysis*; D017747:Seafood / Q000032:analysis; D014835:Volatilization
chemical_list: D009602:Nitrosamines