title: A remote Lewis acid trigger dramatically accelerates biaryl reductive elimination from a platinum complex.
abstract: A strategy for the control of electron density at a metal center is reported, which uses a remote chemical switch involving second-sphere Lewis acid binding that modulates electron density in the first coordination sphere. Binding of the Lewis acid B(C6F5)3 at remote nitrogen positions of a bipyrazine-diarylplatinum(II) complex accelerates biaryl reductive elimination by a factor of 64,000.
authors.affiliation: Department of Chemistry, University of California - Berkeley, Berkeley, California 94720, USA.
authors.forename: Allegra L
authors.initials: AL
authors.lastname: Liberman-Martin
authors.forename: Robert G
authors.initials: RG
authors.lastname: Bergman
authors.forename: T Don
authors.initials: TD
authors.lastname: Tilley
mesh_terms: D058116:Lewis Acids / Q000737:chemistry*; D015394:Molecular Structure; D009944:Organoplatinum Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D011719:Pyrazines / Q000737:chemistry*
chemical_list: D058116:Lewis Acids; D009944:Organoplatinum Compounds; D011719:Pyrazines