title: Mean platelet volume in recurrent aphthous stomatitis and Behçet disease.
abstract: Behcet disease (BD) and recurrent aphthous stomatitis (RAS) are systemic inflammatory diseases, but the exact pathogenesis of both the diseases is unknown. Mean platelet volume (MPV) is an indicator of platelet activation. The aim of this study was to investigate the MPV levels in patients with BD, RAS, and healthy participants. A total of 61 patients with BD, 60 patients with RAS, and 60 healthy controls were included in this study. The MPV levels and erythrocyte sedimentation rate in patients with BD and RAS groups were significantly higher than the control groups (P < .001). In the BD group as well as in the RAS group, the disease activity does not affect the levels of MPV. The MPV levels may be used as a cheap and feasible diagnostic marker in patients with BD and RAS. Nevertheless, the MPV does not have a predictive value in differentiating the diagnosis of BD and RAS.
authors.affiliation: 1Department of Dermatology, School of Medicine, Mustafa Kemal University, Hatay, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Ekiz
authors.forename: Ilknur
authors.initials: I
authors.lastname: Balta
authors.forename: Bilge Bulbul
authors.initials: BB
authors.lastname: Sen
authors.forename: Emine Nur
authors.initials: EN
authors.lastname: Rifaioglu
authors.forename: Can
authors.initials: C
authors.lastname: Ergin
authors.forename: Sevket
authors.initials: S
authors.lastname: Balta
authors.forename: Sait
authors.initials: S
authors.lastname: Demirkol
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D015539:Platelet Activation / Q000502:physiology; D012008:Recurrence; D013281:Stomatitis, Aphthous / Q000175:diagnosis* / Q000503:physiopathology
keywords: Behcet disease; mean platelet volume; recurrent aphthous stomatitis; vascular