title: Diagnosis of right ventricular cardiac sarcoidosis with cardiac magnetic resonance in a patient presenting with ventricular tachycardia.
abstract: Sarcoidosis patients often have myocardial involvement, however, very few have clinically significant cardiac disease and ventricular tachycardia as the initial presentation is exceedingly rare. We report the case of a middle-aged male with symptomatic but clinically stable ventricular tachycardia. Chest radiograph, computed tomography, and positron emission tomography demonstrated pulmonary and mediastinal abnormalities but no definitive etiology for his arrhythmia. Transthoracic echocardiogram revealed the nonspecific cardiac abnormalities of right ventricular dilation and septal flattening. Cardiac magnetic resonance demonstrated delayed enhancement and akinesia of the right ventricular free and inferior walls--virtually diagnostic of an infiltrative myocardial disease. The diagnosis was then verified with transbronchial biopsy showing noncaseating granulomas consistent with sarcoidosis. In conclusion, this case illustrates an unusual presentation of sarcoidosis and demonstrates how the diagnosis can be made using cardiac magnetic resonance alongside transbronchial biopsy.
authors.affiliation: NMCSD Department of Internal Medicine, 34800 Bob Wilson Drive, Building 3 Floor 3, San Diego, CA 92134, USA.
authors.forename: Luke
authors.initials: L
authors.lastname: Oakley
authors.forename: James
authors.initials: J
authors.lastname: Prahl
authors.forename: Massoud
authors.initials: M
authors.lastname: Daheshia
authors.forename: Gregory
authors.initials: G
authors.lastname: Price
authors.forename: Gilbert
authors.initials: G
authors.lastname: Boswell
authors.forename: Scott
authors.initials: S
authors.lastname: Alexander
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004452:Echocardiography / Q000379:methods*; D004562:Electrocardiography; D006331:Heart Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D012507:Sarcoidosis / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D017180:Tachycardia, Ventricular / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed / Q000379:methods*