title: [Function and mechanism of tumor suppressor gene FBW7 in tumorigenesis].
authors.forename: Hui-jie
authors.initials: HJ
authors.lastname: Huang
authors.forename: Fang
authors.initials: F
authors.lastname: Zheng
authors.forename: Fang-ping
authors.initials: FP
authors.lastname: Xu
authors.forename: Yan-hui
authors.initials: YH
authors.lastname: Liu
authors.forename: Heng-guo
authors.initials: HG
authors.lastname: Zhuang
mesh_terms: D000818:Animals; D063646:Carcinogenesis; D018797:Cell Cycle Proteins / Q000235:genetics* / Q000378:metabolism; D019927:Cyclin E / Q000378:metabolism; D044783:F-Box Proteins / Q000235:genetics* / Q000378:metabolism; D000073979:F-Box-WD Repeat-Containing Protein 7; D020868:Gene Silencing; D016147:Genes, Tumor Suppressor; D006801:Humans; D009154:Mutation; D064549:Myeloid Cell Leukemia Sequence 1 Protein / Q000378:metabolism; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D016271:Proto-Oncogene Proteins c-myc / Q000378:metabolism; D051880:Receptors, Notch / Q000378:metabolism; D015398:Signal Transduction; D058570:TOR Serine-Threonine Kinases / Q000378:metabolism; D044767:Ubiquitin-Protein Ligases / Q000235:genetics* / Q000378:metabolism
chemical_list: D018797:Cell Cycle Proteins; D019927:Cyclin E; D044783:F-Box Proteins; D000073979:F-Box-WD Repeat-Containing Protein 7; C513273:FBXW7 protein, human; C579095:MCL1 protein, human; D064549:Myeloid Cell Leukemia Sequence 1 Protein; D016271:Proto-Oncogene Proteins c-myc; D051880:Receptors, Notch; D044767:Ubiquitin-Protein Ligases; D058570:TOR Serine-Threonine Kinases