title: False-positive iodine-131 whole body scan due to a benign dermal lesion; intradermal nevus ((131)I uptake in a benign nevus).
abstract: Whole body radioiodine scanning (WBS), along with plasma thyroglobulin level, remains a reference method for detecting residual or metastatic differentiated thyroid cancer, however, false-positive WBS is not uncommon. External contaminations by body secretions or excretions, inflammation, and cystic structures mimicking metastases in WBS have been reported. Various benign and malignant tumors having different histopathological natures accumulate radioiodine, but intradermal melanocytic nevus was not previously described in the literature, as far as we know. This report describes an unusual cause of false-positive WBS after radioablation therapy due to an intradermal nevus, and the possible mechanisms are discussed.
authors.affiliation: Department of Nuclear Medicine, Ankara Ataturk Research and Training Hospital, Ankara, Turkey, nypoyraz@yahoo.com.
authors.forename: Nilufer
authors.initials: N
authors.lastname: Yildirim-Poyraz
authors.forename: Elif
authors.initials: E
authors.lastname: Ozdemir
authors.forename: Cagla
authors.initials: C
authors.lastname: Amutkan
authors.forename: Nuran
authors.initials: N
authors.lastname: Adiyaman
authors.forename: Sule
authors.initials: S
authors.lastname: Kilinc
authors.forename: Zuhal
authors.initials: Z
authors.lastname: Kandemir
authors.forename: Fatma
authors.initials: F
authors.lastname: Saglam
authors.forename: Seyda
authors.initials: S
authors.lastname: Turkolmez
authors.forename: Bekir
authors.initials: B
authors.lastname: Cakir
mesh_terms: D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D008875:Middle Aged; D018330:Nevus, Intradermal / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D012878:Skin Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D051598:Whole Body Imaging
chemical_list: D007457:Iodine Radioisotopes