title: [Phylogenetic analysis and genotyping of A/H3N2 Influenza viruses isolated from patients hospitalised with influenza-like illness symptoms in the na bulovce hospital in the season 2011/2012].
abstract: Influenza A virus is an important cause of acute respiratory infections (ARI). Clinical manifestations of ARI vary from mild or moderate to life-threatening conditions requiring intensive care. Given the segmented genome, a large natural reservoir of other influenza virus subtypes, and antibody selection pressure in the population, the virus is variable and genetically unstable. The phylogenetic analysis and genotyping of A/H3N2 influenza viruses isolated from patients hospitalised with influenza-like illness symptoms in the Na Bulovce Hospital in the season 2011/2012 support the assumption that the pathogenicity is a polygenic trait modifiable by the host health status and seems not to be unambiguously associated with any specific mutations.
authors.affiliation: Státní Zdravotní ústav, Centrum Epidemiologie a Mikrobiologie, Praha. alexandernagy17@hotmail.com
authors.forename: Alexander
authors.initials: A
authors.lastname: Nagy
authors.forename: Helena
authors.initials: H
authors.lastname: Jiřincová
authors.forename: Martina
authors.initials: M
authors.lastname: Havlíčková
authors.forename: Olga
authors.initials: O
authors.lastname: Džupová
authors.forename: Kristýna
authors.initials: K
authors.lastname: Herrmannová
authors.forename: Milan
authors.initials: M
authors.lastname: Trojánek
authors.forename: Vilma
authors.initials: V
authors.lastname: Marešová
authors.forename: Ludmila
authors.initials: L
authors.lastname: Nováková
authors.forename: Jan
authors.initials: J
authors.lastname: Kynčl
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005838:Genotype; D006801:Humans; D053122:Influenza A Virus, H3N2 Subtype / Q000145:classification / Q000235:genetics*; D007251:Influenza, Human / Q000175:diagnosis / Q000821:virology*; D008297:Male; D008875:Middle Aged; D010802:Phylogeny