title: Chondroid chordoma in an atypical location.
abstract: Chondroid chordoma is an extremely rare tumour with an annual incidence of around 0.1 cases per 100,000population. Involvement of the thoracic vertebrae may be present in 2-5% of cases. Definitive diagnosis usually requires a suitable distinction between this and other mesenchymal tumours such as chondrosarcomas, so immunohistochemical analysis is virtually mandatory. In spite of its slow-growing nature, chondroid chordoma tends to relapse, and it may eventually become malignant, often jeopardising the patient's prognosis. Although surgery remains the main therapeutic approach, research into the molecular and genetic aspects of this tumour is ongoing. These new advances are likely to improve future oncology therapies by complementing surgery and radiotherapy, changing the currently poor prognosis. We report the case of a patient with a chondroid chordoma involving the thoracic vertebrae and pleural cavity, and the treatment performed.
authors.affiliation: Servicio de Cirugía Torácica, Hospital Universitario Miguel Servet y Hospital Clínico Universitario Lozano Blesa, Zaragoza, España. Electronic address: ircres@hotmail.com.
authors.forename: Iñigo
authors.initials: I
authors.lastname: Royo Crespo
authors.forename: Juan José
authors.initials: JJ
authors.lastname: Rivas de Andrés
authors.forename: Raúl
authors.initials: R
authors.lastname: Embún Flor
authors.forename: Severiano
authors.initials: S
authors.lastname: Cortés Franco
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002817:Chordoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary / Q000628:therapy; D003131:Combined Modality Therapy; D003475:Curettage; D003951:Diagnostic Errors; D003964:Diaphragm / Q000473:pathology; D004443:Echinococcosis / Q000175:diagnosis; D066246:ErbB Receptors / Q000037:antagonists & inhibitors; D006801:Humans; D007796:Laminectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000556:secondary; D009361:Neoplasm Invasiveness; D009363:Neoplasm Proteins / Q000037:antagonists & inhibitors; D035422:Pleural Cavity / Q000000981:diagnostic imaging / Q000473:pathology*; D010997:Pleural Neoplasms / Q000556:secondary; D019736:Prostheses and Implants; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use; D018714:Radiotherapy, Adjuvant; D012074:Remission Induction; D012509:Sarcoma / Q000175:diagnosis; D013899:Thoracic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D009363:Neoplasm Proteins; D047428:Protein Kinase Inhibitors; C512478:EGFR protein, human; D066246:ErbB Receptors
keywords: Chondroid chordoma; Clasificación; Classification; Cordoma condroide; Tratamiento; Treatment; Tumor vertebral; Vertebral tumour