title: [Character of changes in the rheological parameters of blood in patients with heart failure III-IV FC treated by the combination therapy with plasmapheresis].
abstract: The purpose of the investigation is to estimate the blood rheological parameters in patients with heart failure III-IV FC treated by the combination therapy (plasmapheresis with the standard therapy). There were 96 patients under the investigations, 69 men and 27 women. Age ranged from 55 to 75 years. All patients were divided into two groups: the 1st group--29 patients (20 men and 9 women) treated by standard therapy (ACE inhibitors, diuretics, digoxin and etc.), the 2nd group included 67 patients (49 men and 18 women), which received the combination therapy with plasmapheresis (2-4 times). The investigations of the blood rheological parameters in patients with heart failure III-IV FC treated by the standard therapy and by the combination therapy show the benefit of the combined one. It was proved by the statistically significant decrease of prothrombin time, fibrinogen, antithrombin III and haematocrit indicator in patients with heart failure treated with the combined therapy (in comparison with patients treated with standard therapy). Patients treated with the combined therapy demonstrated low blood viscosity levels -BV20, BV200 and high erythrocyte deformability index.
authors.forename: Iu E
authors.initials: IuE
authors.lastname: Mal'chevskiĭ
mesh_terms: D000368:Aged; D001809:Blood Viscosity / Q000502:physiology*; D004912:Erythrocytes / Q000473:pathology; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis; D012212:Rheology / Q000379:methods*; D016896:Treatment Outcome