title: Gastrointestinal and liver disease in pregnancy.
abstract: Gastrointestinal (GI) conditions are common in women of childbearing age. They often present before pregnancy but can arise de novo during pregnancy. The physiological changes that occur during pregnancy can influence the differential diagnosis of common GI presentations, affect the interpretation of diagnostic tests and restrict the use of diagnostic or therapeutic procedures. In this article, we summarise the clinical features, investigation and management of common GI and liver conditions that are incidental to pregnancy, and describe the specific features of pregnancy-related disorders that are less frequently encountered by general physicians. Newer developments in areas that are increasingly encountered in obstetric medical practice, including pregnancy after bariatric procedures, are also described.
authors.affiliation: Oxford University Hospitals NHS Trust, Oxford, UK.
authors.forename: Charlotte J
authors.initials: CJ
authors.lastname: Frise
authors.forename: Catherine
authors.initials: C
authors.lastname: Williamson
mesh_terms: D050110:Bariatric Surgery / Q000379:methods; D015992:Body Mass Index; D002780:Cholestasis, Intrahepatic / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D005767:Gastrointestinal Diseases / Q000175:diagnosis* / Q000628:therapy; D017359:HELLP Syndrome / Q000175:diagnosis; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000175:diagnosis* / Q000628:therapy; D008107:Liver Diseases / Q000175:diagnosis* / Q000628:therapy; D009765:Obesity / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis; D011256:Pregnancy Outcome; D016896:Treatment Outcome
keywords: HELLP syndrome; Pregnancy; hyperemesis gravidarum; hypertensive disorders of pregnancy; liver disease; obstetric cholestasis