title: Virchow lymph node metastatic recurrence of sigmoid colon cancer with severe lymph node metastases successfully treated using systemic chemotherapy combined with radiotherapy.
abstract: Metastatic recurrence of colon cancer in the left supraclavicular lymph node (Virchow lymph node) is rare, and to date there are no reports on radiotherapy as treatment. We report on a case of metastatic recurrence of sigmoid colon cancer in the Virchow lymph node with severe lymph node metastases successfully treated with a combined modality therapy of systemic chemotherapy and radiotherapy. The case is of a 58-year-old man, who underwent sigmoid excision and lymph node excision, and subsequently received systemic chemotherapy. After left supraclavicular lymph node recurrence appeared he later received radiotherapy. Complete response was achieved, and there has been no further recurrence, to date, 10 months after the radiotherapy. Radiotherapy was effective as a local treatment, and local control of distant metastasis of colonic cancer may lead to a good prognosis.
authors.affiliation: Department of Surgery, Faculty of Medicine, Kurume University, Fukuoka, Japan. ohchi_takafumi@med.kurume-u.ac.jp
authors.forename: Takafumi
authors.initials: T
authors.lastname: Ohchi
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Akagi
authors.forename: Tetsushi
authors.initials: T
authors.lastname: Kinugasa
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Ishibashi
authors.forename: Natsuki
authors.initials: N
authors.lastname: Tanaka
authors.forename: Shinya
authors.initials: S
authors.lastname: Fujino
authors.forename: Shiro
authors.initials: S
authors.lastname: Kibe
authors.forename: Kotaro
authors.initials: K
authors.lastname: Yuge
authors.forename: Teruo
authors.initials: T
authors.lastname: Sasatomi
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Mizobe
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Oka
authors.forename: Kawang Dae
authors.initials: KD
authors.lastname: Hong
authors.forename: Kazuo
authors.initials: K
authors.lastname: Shirouzu
mesh_terms: D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000068258:Bevacizumab; D000069287:Capecitabine; D059248:Chemoradiotherapy; D002968:Clavicle / Q000473:pathology*; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D005472:Fluorouracil / Q000008:administration & dosage / Q000031:analogs & derivatives; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000628:therapy*; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D000077150:Oxaliplatin; D011379:Prognosis; D012074:Remission Induction; D012811:Sigmoid Neoplasms / Q000556:secondary / Q000628:therapy*
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; D003841:Deoxycytidine; D000068258:Bevacizumab; D000069287:Capecitabine; D005472:Fluorouracil
keywords: Colon cancer; Virchow lymph node metastasis; combination therapy