title: Metal-mediated coupling of a coordinated isocyanide and indazoles.
abstract: A reaction between equimolar amounts of cis-[PdCl2(CNCy)2] (1) and indazole (HInd, 2) or 5-methylindazole (HInd(Me), 3) proceeded in refluxing CHCl3 for ca. 6 h affording the aminocarbene species cis-[PdCl2{C(Ind)=N(H)Cy}(CNCy)] (4) or cis-[PdCl2{C(Ind(Me))=N(H)Cy}(CNCy)] (5) in good (72-83%) isolated yields. Complexes 4 and 5 were characterized by elemental analyses (C, H, N), HR ESI(+)-MS, IR, and 1D ((1)H, (13)C{(1)H}) and 2D ((1)H,(1)H-COSY, (1)H,(13)C-HMQC/(1)H,(13)C-HSQC, (1)H,(13)C-HMBC) NMR spectroscopies, and complex 4 as well by X-ray diffraction. The observed coupling represents the first example of metal-mediated integration between any isocyanide and any aromatic heterocyclic system having an HN center.
authors.affiliation: Department of Chemistry, Saint Petersburg State University, Petrodvorec, Universitetskiy pr. 26, 198504 Saint Petersburg, Russian Federation.
authors.forename: Mikhail A
authors.initials: MA
authors.lastname: Kinzhalov
authors.forename: Vadim P
authors.initials: VP
authors.lastname: Boyarskiy
authors.forename: Konstantin V
authors.initials: KV
authors.lastname: Luzyanin
authors.forename: Fedor M
authors.initials: FM
authors.lastname: Dolgushin
authors.forename: Vadim Yu
authors.initials: VY
authors.lastname: Kukushkin