title: Comparison of seminal oxidants and antioxidants in subjects with different levels of physical fitness.
abstract: The purpose of this study was to evaluate the seminal 8-Isoprostane, reactive oxygen species (ROS), malondialdehyde (MDA), superoxide dismutase (SOD), catalase, total antioxidant capacity (TAC) in subjects with different level of physical fitness. A total of 161 semen samples were obtained from three groups of healthy males, including elite athletes (23.8 ± 5.2 years, n = 56) who had regular training (4-5 days per week), recreationally active men (24.2 ± 4.9 years, n = 52) who participated in educational or recreational physical activities for 4-5 h per week and non-active men (23.9 ± 5.0 years, n = 53) who did not participate in any exercise programmes for at least 6 months prior to the study. The results showed significantly higher levels of SOD, catalase and TAC as well as lower levels of 8-Isoprostane, ROS and MDA in recreationally active men compared with either elite athletes or non-active men (p < 0.001). Also, elite athletes revealed significantly higher seminal 8-Isoprostane, ROS and MDA as well as lower SOD, catalase and TAC levels compared with recreationally active and non-active men (p < 0.001). In conclusion, the results of the present study indicate that there are differences in seminal oxidants and antioxidants of elite athletes, recreationally active and non-active men. These differences are more likely related to indices that favour decrement of oxidative stress-induced peroxidative damage in spermatozoa from recreationally active men. Hence, recreationally active men seem to have a healthier semen production. The physiological significance of this observation is worthy of further investigation.
authors.affiliation: Department of Exercise Physiology, Faculty of Physical Education and Sport Science, Urmia University, Urmia, Iran. hajizadeh.sci.phys@gmail.com
authors.forename: B
authors.initials: B
authors.lastname: Hajizadeh Maleki
authors.forename: B
authors.initials: B
authors.lastname: Tartibian
authors.forename: M
authors.initials: M
authors.lastname: Eghbali
authors.forename: S
authors.initials: S
authors.lastname: Asri-Rezaei
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D000975:Antioxidants / Q000032:analysis*; D015415:Biomarkers / Q000032:analysis; D002374:Catalase / Q000032:analysis; D015237:Dinoprost / Q000031:analogs & derivatives / Q000032:analysis; D005080:Exercise Test; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000032:analysis; D016877:Oxidants; D018384:Oxidative Stress; D010809:Physical Fitness; D017382:Reactive Oxygen Species / Q000032:analysis; D012661:Semen / Q000737:chemistry*; D055101:Semen Analysis; D013482:Superoxide Dismutase / Q000032:analysis; D055815:Young Adult
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D016877:Oxidants; D017382:Reactive Oxygen Species; C075750:8-epi-prostaglandin F2alpha; D008315:Malondialdehyde; D015237:Dinoprost; D002374:Catalase; D013482:Superoxide Dismutase