title: Understanding the current status of image-guided ablation for metastatic colorectal disease.
abstract: Colorectal metastases to the liver are increasingly being detected and accurately characterized at an earlier stage and even at the subcentimeter level. The oncological case for surgical resection of this disease is widely accepted. The advent of smaller volume disease has encouraged the development of in situ ablative technologies over the last two decades and the oncological efficacy of these procedures has continued to improve through stepwise developments in ablation devices and image guidance. This article provides an overview of these techniques, currently available and future technologies, and the imaging findings encountered. It also sets out the current position image-guided ablation merits alongside chemotherapy and surgical resection. In selected cases ablation for colorectal metastases can produce oncological outcomes equivalent to surgery and critically with less morbidity in an increasingly older patient population. We examine whether with careful patient selection, optimal technology, meticulous technique, and diligent follow-up, consistently reproducible high quality outcomes will be achieved in the next few years.
authors.affiliation: Department of Radiology, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD, UK.
authors.forename: Alexander J
authors.initials: AJ
authors.lastname: King
authors.forename: David J
authors.initials: DJ
authors.lastname: Breen
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D017115:Catheter Ablation / Q000379:methods*; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D053783:Magnetic Resonance Imaging, Interventional; D018579:Patient Selection; D015641:Radiography, Interventional; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents