title: Eosinophilic meningitis caused by primary angiitis of the central nervous system.
abstract: Eosinophilic meningitis is defined as the presence of 10 eosinophils/mm(3) in the cerebrospinal fluid (CSF) or eosinophils accounting for more than 10% of CSF leukocytes. A 76-year-old man who developed cognitive dysfunction and consciousness disturbance had eosinophilic meningitis (his CSF contained 19.0% eosinophils). Because the etiology was unknown, we performed a brain biopsy. The pathological findings showed inflammatory infiltration in the small-sized arteries of the meninges. The patient was ultimately diagnosed as having primary angiitis of the central nervous system (PACNS). Eosinophilic meningitis occurring in a patient with PACNS is extremely rare, and this is the first report of this condition in Japan.
authors.affiliation: Department of Neurology, Juntendo University School of Medicine, Japan.
authors.forename: Kazuoki
authors.initials: K
authors.lastname: Hirano
authors.forename: Jiro
authors.initials: J
authors.lastname: Fukae
authors.forename: Sotaro
authors.initials: S
authors.lastname: Hieda
authors.forename: Motoki
authors.initials: M
authors.lastname: Fujimaki
authors.forename: Hisato
authors.initials: H
authors.lastname: Ishii
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Tsuboi
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Kawamura
authors.forename: Hajime
authors.initials: H
authors.lastname: Arai
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Hattori
mesh_terms: D000368:Aged; D004802:Eosinophilia / Q000134:cerebrospinal fluid / Q000209:etiology*; D004804:Eosinophils; D006801:Humans; D007958:Leukocyte Count; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000209:etiology*; D020293:Vasculitis, Central Nervous System / Q000150:complications* / Q000175:diagnosis