title: [Hypoparathyroidism and hypogonadism as a clinical manifestation of hemochromatosis].
abstract: Primary hypoparathyroidism is a disease in which the parathyroid glands decrease or cease secretion of parathyroid hormone, leading to clinically significant hypocalcemia. Although considered a rare condition, hypoparathyroidism seems to occur much more frequently than reported. In most cases, hypoparathyroidism remains a complication of neck surgery. However, many other pathologic conditions may be implicated in its pathogenesis. Here we present a case of a patient in whom hypoparathyroidism developed as a complication of hereditary hemochromatosis and was followed by hypogonadism, representing an atypical clinical manifestation of this disorder. In the article, we describe the diagnostic and treatment strategies undertaken in this patient. Our case study suggests that every person with hypoparathyroidism of unknown origin, particularly if this disorder is accompanied by abnormal gonadal function, should be assessed for the possible presence of hereditary hemochromatosis.
authors.affiliation: Klinika Chorób Wewnetrznych i Farmakologii Klinicznej Katedry Farmakologii Slaskiego Uniwersytetu Medycznego w Katowicach. r.krysiak@interia.pl
authors.forename: Robert
authors.initials: R
authors.lastname: Krysiak
authors.forename: Bogusław
authors.initials: B
authors.lastname: Okopień
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D006432:Hemochromatosis / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D007006:Hypogonadism / Q000175:diagnosis / Q000209:etiology*; D007011:Hypoparathyroidism / Q000175:diagnosis / Q000209:etiology*; D008297:Male