title: Maternal-neonatal transfusion compatibility irrespective of ABO mismatch--a prospective observational study.
abstract: OBJECTIVE
  To determine transfusion compatibility of maternal RBCs for her neonate up to 4 weeks of age, irrespective of maternal-neonatal ABO mismatch.
  
  
  METHODS
  This was a prospective observational study involving eligible mothers with their neonates delivered in participating site from 1 July 2012 till 31 December 2012. Mother's blood was collected before child birth. Neonatal blood sample was collected from placental end, shortly after birth. Blood Groups of mother-baby pair were individually tested for ABO and Rh-D groups. Pairs with negative Rh-D antigen/s or with same ABO blood groups were excluded. Thus, 28 pairs with both maternal and neonatal samples positive for Rh-D antigen and with different maternal neonatal ABO blood groups were included in the study. Blood samples were collected at birth and at 4 weeks. Cross matching was done at birth and at 4 weeks for each pair with standard blood bank protocols.
  
  
  RESULTS
  All 28 pairs showed positive compatibility with standard blood bank cross-matching protocols at birth and at 4 weeks.
  
  
  CONCLUSIONS
  Maternal blood irrespective of ABO compatibility might be a viable and potentially acceptable option for her new born baby in neonatal period. This may be especially important in developing world with limited blood bank resources.
authors.affiliation: Department of Pediatrics and Neonatology, Rajhans Hospital and Research Center , Saphale , India .
authors.forename: S G
authors.initials: SG
authors.lastname: Gokhale
authors.forename: M
authors.initials: M
authors.lastname: Ranadive
authors.forename: R
authors.initials: R
authors.lastname: Chouhan
authors.forename: S
authors.initials: S
authors.lastname: Gokhale
mesh_terms: D000017:ABO Blood-Group System / Q000276:immunology*; D001787:Blood Group Incompatibility / Q000097:blood / Q000175:diagnosis / Q000276:immunology*; D001788:Blood Grouping and Crossmatching; D017707:Erythrocyte Transfusion / Q000379:methods*; D005260:Female; D006801:Humans; D007108:Immune Tolerance; D007231:Infant, Newborn; D011446:Prospective Studies; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
chemical_list: D000017:ABO Blood-Group System; D012204:Rh-Hr Blood-Group System