title: Heteroatom-guided, palladium-catalyzed regioselective C-H functionalization in the synthesis of 3-arylquinolines.
abstract: A new approach for the regioselective functionalization of the C-3-position of quinolines is described. The method utilizes heteroatom guided regioselective C-3 palladation followed by arylation via transmetalation with aryl boronic acids to yield 3-aryl-N-acyl-1,2-dihydroquinolines. In a one-pot sequence, N-deacylation followed by aromatization leads to important 3-arylquinolines in good yields.
authors.affiliation: Department of Chemistry, Indian Institute of Science Education and Research Bhopal, ITI (Gas Rahat) Building, Raisen Road, Bhopal 462023, India.
authors.forename: Virendra Kumar
authors.initials: VK
authors.lastname: Tiwari
authors.forename: Govind Goroba
authors.initials: GG
authors.lastname: Pawar
authors.forename: Riki
authors.initials: R
authors.lastname: Das
authors.forename: Amit
authors.initials: A
authors.lastname: Adhikary
authors.forename: Manmohan
authors.initials: M
authors.lastname: Kapur