title: Fluorescent labeling agents for quorum-sensing receptors (FLAQS) in live cells.
abstract: Lighten up: A selective fluorescent-labeling agent for quorum sensing (FLAQS) can be used for the visualization of the communication pathway of bacteria in live cells (see figure). This represents a new, operationally simple, fast, and inexpensive tool for the imaging of quorum-sensing receptors by using fluorescently labeled signaling-molecule analogues.
authors.affiliation: Department of Chemistry, University of Basel, National Centre of Competence in Research Chemical Biology, St. Johanns-Ring 19, 4056 Basel, Switzerland.
authors.forename: José
authors.initials: J
authors.lastname: Gomes
authors.forename: Natalie
authors.initials: N
authors.lastname: Huber
authors.forename: Alexander
authors.initials: A
authors.lastname: Grunau
authors.forename: Leo
authors.initials: L
authors.lastname: Eberl
authors.forename: Karl
authors.initials: K
authors.lastname: Gademann
mesh_terms: D054742:Acyl-Butyrolactones / Q000138:chemical synthesis* / Q000737:chemistry; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D015374:Biosensing Techniques; D057508:Burkholderia cenocepacia / Q000378:metabolism*; D002450:Cell Communication; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D055786:Gene Knockout Techniques; D049452:Green Fluorescent Proteins / Q000737:chemistry; D057054:Molecular Imaging; D009154:Mutation; D016958:Pseudomonas putida / Q000378:metabolism; D053038:Quorum Sensing
chemical_list: D054742:Acyl-Butyrolactones; D001426:Bacterial Proteins; C117246:CepR protein, Burkholderia; D005456:Fluorescent Dyes; D049452:Green Fluorescent Proteins
keywords: Burkholderia cenocepacia; cell recognition; fluorescent probes; lactones; quorum sensing