title: Management and outcome of consecutive pregnancies complicated by idiopathic intracranial hypertension.
abstract: BACKGROUND
  The effects of consecutive pregnancies on the course of idiopathic intracranial hypertension (IIH) are unclear in view of the scarce published data.
  
  
  OBJECTIVE
  To evaluate the course and management of visual and pregnancy outcomes of consecutive pregnancies with IIH.
  
  
  METHODS
  The medical records of women with IIH in consecutive pregnancies were reviewed for neuro-ophthalmological findings, management, and visual and pregnancy outcomes.
  
  
  RESULTS
  The study group comprised eight women with at least two consecutive pregnancies (mean age 27.3 +/- 5.3 years). The mean duration of IIH prior to the first pregnancy was 3.4 +/- 3.16 years. One woman with IIH pre-pregnancy symptoms and three women with clinical features of IIH during the second trimester of pregnancy (gestational week 21.7 +/- 4.04) were treated with acetazolamide (250 mg every 8 hours). Symptoms resolved, resulting in uncomplicated first deliveries for all four. The first deliveries of four other women were by cesarean section due to obstetric indications. Only one woman developed symptoms and signs of IIH during her second pregnancy and was thus treated with acetazolamide. Two women who completed three pregnancies had no IIH symptoms during their pregnancies. The course and outcome of those pregnancies were normal.
  
  
  CONCLUSIONS
  IIH apparently does not worsen or even become symptomatic in consecutive pregnancies. The appropriate management of IIH in pregnant women is similar to management for non-pregnant women; neither the course nor the obstetric outcome of first and consecutive pregnancies is influenced by the presence of IIH.
authors.affiliation: Neuro-Ophthalmology Unit, Department of Ophthalmology, Tel Aviv Sourasky Medical Center, Tel Aviv, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel. shanigola2@gmail.com
authors.forename: Shani
authors.initials: S
authors.lastname: Golan
authors.forename: Sharon
authors.initials: S
authors.lastname: Maslovitz
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Kupferminc
authors.forename: Anat
authors.initials: A
authors.lastname: Kesler
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use; D000328:Adult; D002257:Carbonic Anhydrase Inhibitors / Q000627:therapeutic use; D002585:Cesarean Section / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology* / Q000628:therapy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D013997:Time Factors; D055815:Young Adult
chemical_list: D002257:Carbonic Anhydrase Inhibitors; D000086:Acetazolamide