title: Efficacy of the use of a colorimetric pupil light reflex device in the diagnosis of fundus disease or optic pathway disease in dogs.
abstract: The aim of this study was to determine the efficacy of a colorimetric pupil light reflex (PLR) device (Melan-100(®), U.S.A.) in dogs with sudden acquired retinal degeneration syndrome (SARDS; 16 cases), progressive retinal atrophy (PRA; 10 cases) and optic pathway disease (6 cases). The colorimetric device detected PLR abnormality in 32, 16 and 9 eyes with SARDS, PRA and optic pathway disease, respectively, whereas white light detected PLR abnormality in 18, 11 and 9 eyes with SARDS, PRA and optic pathway disease, respectively. SARDS dogs displayed miosis, while optic pathway disease dogs displayed mydriasis in a blue light examination. Thus, colorimetric PLR may be a useful method for determining whether electroretinography (ERG) or magnetic resonance imaging (MRI) should be performed for dogs with acute blindness.
authors.affiliation: Department of Veterinary Surgery, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan.
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Terakado
authors.forename: Takuya
authors.initials: T
authors.lastname: Yogo
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Nezu
authors.forename: Yasuji
authors.initials: Y
authors.lastname: Harada
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Hara
authors.forename: Masahiro
authors.initials: M
authors.lastname: Tagawa
mesh_terms: D000818:Animals; D001766:Blindness / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D008297:Male; D009900:Optic Nerve / Q000473:pathology*; D011237:Predictive Value of Tests; D012025:Reflex, Pupillary / Q000502:physiology*; D012162:Retinal Degeneration / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity