title: URI in athletes: are mucosal immunity and cytokine responses key risk factors?
abstract: Infection incidence among athletes is highest during periods of intensified training and competition and after strenuous long-distance events. Which aspects of depressed immune function are responsible for this increased infection risk are not known, but our hypothesis is that lower salivary immunoglobulin A (IgA) secretion and a higher antiinflammatory cytokine response to antigen exposure are key determinants of infection risk.
authors.affiliation: School of Sport, Exercise & Health Sciences, Loughborough University, Loughborough, Leicestershire, UK. M.Gleeson@lboro.ac.uk
authors.forename: Michael
authors.initials: M
authors.lastname: Gleeson
authors.forename: Nicolette C
authors.initials: NC
authors.lastname: Bishop
mesh_terms: D056352:Athletes; D016207:Cytokines / Q000378:metabolism; D015444:Exercise / Q000502:physiology*; D006801:Humans; D018928:Immunity, Mucosal; D012141:Respiratory Tract Infections / Q000276:immunology* / Q000378:metabolism; D050378:T-Lymphocytes, Regulatory / Q000502:physiology
chemical_list: D016207:Cytokines