title: [Prevalence, features of circulation, and diversity of human parechoviruses in Nizhny Novgorod].
abstract: A total of 5230 specimens from children with gastroenteritis collected in Nizhny Novgorod in 2006-2010 were screened for human parechoviruses (HPeV). HPeV were observed every year with mean frequency of 6.16%. The majority of HpeV (65.83%) was detected in children younger than 3 years. The typing of 71 detected HPeV with the use of partial sequencing of the VP3-VP1 region revealed the presence of HPeV1 (91.55%), HpeV6 (5.63%), HPeV3 (3.08%), HPeV4 (1.54%). HPeV1B was predominant among HPeV1, HPeV1A was identified rarely. Six stains of HPEV1 formed separate phylogenetic cluster, had sequence gomology with HPEV1A or HPeV1B not more than 88% and could be characterized as members of a separate genotype HPeV1.
authors.forename: L N
authors.initials: LN
authors.lastname: Golitsina
authors.forename: V V
authors.initials: VV
authors.lastname: Zverev
authors.forename: N A
authors.initials: NA
authors.lastname: Novikova
authors.forename: S G
authors.initials: SG
authors.lastname: Fomina
authors.forename: O V
authors.initials: OV
authors.lastname: Parfenova
authors.forename: N V
authors.initials: NV
authors.lastname: Epifanova
authors.forename: L B
authors.initials: LB
authors.lastname: Lukovnikova
authors.forename: O V
authors.initials: OV
authors.lastname: Morozova
authors.forename: N V
authors.initials: NV
authors.lastname: Ponomareva
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D030061:Parechovirus / Q000235:genetics*; D010802:Phylogeny; D010850:Picornaviridae Infections / Q000453:epidemiology* / Q000235:genetics*; D015995:Prevalence; D012426:Russia / Q000453:epidemiology