title: Facile synthesis of benzofurans via copper-catalyzed aerobic oxidative cyclization of phenols and alkynes.
abstract: Regioselective synthesis of polysubstituted benzofurans using a copper catalyst and molecular oxygen from phenols and alkynes in a one-pot procedure has been reported. The transformation consists of a sequential nucleophilic addition of phenols to alkynes and oxidative cyclization. A wide variety of phenols and alkynes can be used in the same manner.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zeng
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
authors.forename: Liangbin
authors.initials: L
authors.lastname: Huang
authors.forename: Yadong
authors.initials: Y
authors.lastname: Sun
authors.forename: Zhengwang
authors.initials: Z
authors.lastname: Chen
authors.forename: Xianwei
authors.initials: X
authors.lastname: Li
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D010636:Phenols / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D001572:Benzofurans; D009942:Organometallic Compounds; D010636:Phenols; D003300:Copper