title: [The use of immunological characteristics of the peripheral blood for the purpose of forensic medical expertise of the subjects exposed to ionizing radiation].
abstract: The objective of the present study was the comprehensive evaluation of quantitative and functional metabolic characteristics of human leukocytes following in vitro irradiation of peripheral blood samples at a dose of 0.25, 0.50, 1.0, and 4.0 Gy for the development of a rationale for their application as biological markers of radiation exposure in forensic medical expertise of the subjects affected by supernormal ionizing radiation. The total number of leukocytes, lymphocytes, and their subpopulations as well as the functional and metabolic status of neutrophils were determined. The results of the study indicate the possibility of using a set of functional metabolic characteristics of human leukocytes as the additional forensic medical criteria for diagnostics of radiation impact on living subjects.
authors.forename: A A
authors.initials: AA
authors.lastname: Timoshevskiĭ
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Pigolkin
authors.forename: A N
authors.initials: AN
authors.lastname: Grebeniuk
mesh_terms: D000328:Adult; D001769:Blood / Q000276:immunology / Q000528:radiation effects; D049109:Cell Proliferation / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D005554:Forensic Medicine / Q000379:methods; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007958:Leukocyte Count / Q000379:methods*; D008163:Luminescent Measurements / Q000379:methods; D008297:Male; D018448:Models, Immunological; D011830:Radiation Effects; D011832:Radiation Injuries / Q000209:etiology / Q000276:immunology / Q000473:pathology; D011839:Radiation, Ionizing