title: A practice-based randomised controlled trial of the efficacy of three interventions to reduce dentinal hypersensitivity.
abstract: OBJECTIVE
  The aim of this study was to evaluate the efficacy of three different interventions (non-desensitising toothpaste, desensitising toothpaste and professionally applied dentine bonding agent) in reducing dentinal hypersensitivity over a 2-week, 3-month and 6-month-period in a dental practice setting.
  
  
  METHODS
  This was a randomised controlled, single-blind; parallel-group trial conducted in general dental practice by a single general dental practitioner. Seventy-five subjects were randomly allocated to three groups; non-desensitising toothpaste (NDT), desensitising toothpaste (DT) and professionally applied desensitising agent (DA). Dentinal hypersensitivity was measured using a Visual Analogue Scale (VAS) to record the response from a standardised short blast of air from a triple syringe. Dentinal hypersensitivity was recorded at baseline, two weeks, three months and six months for all groups.
  
  
  RESULTS
  Dentinal hypersensitivity reduced significantly (p<0.0001) in both groups DT and DA, in addition the reduction in sensitivity was sustained and continued to improve over a 6-month-period. The greatest reduction in dentinal hypersensitivity was recorded in group DA.
  
  
  CONCLUSIONS
  The results from this study suggest that application of dentine bonding agents, to teeth diagnosed with dentine hypersensitivity provides the greatest improvement in dentine hypersensitivity at 2 weeks and 6 months. This reduction in dentine hypersensitivity is greater than that achieved by the desensitising toothpaste tested and a non-desensitising toothpaste.
authors.affiliation: Poulton Dental Practice, Poulton Road, Wallasey, Wirral CH44 9DQ, United Kingdom.
authors.forename: M
authors.initials: M
authors.lastname: Gibson
authors.forename: M O
authors.initials: MO
authors.lastname: Sharif
authors.forename: A
authors.initials: A
authors.lastname: Smith
authors.forename: P
authors.initials: P
authors.lastname: Saini
authors.forename: P A
authors.initials: PA
authors.lastname: Brunton
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D045424:Complex Mixtures / Q000627:therapeutic use; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000517:prevention & control*; D017220:Dentin-Bonding Agents / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement / Q000379:methods; D017680:Potassium Compounds / Q000627:therapeutic use; D019279:Resin Cements / Q000627:therapeutic use; D012824:Silicic Acid / Q000627:therapeutic use; D016037:Single-Blind Method; D014099:Toothbrushing / Q000295:instrumentation; D014100:Toothpastes / Q000627:therapeutic use; D016896:Treatment Outcome; D064232:Visual Analog Scale; D055815:Young Adult
chemical_list: D045424:Complex Mixtures; D057133:Dentin Desensitizing Agents; D017220:Dentin-Bonding Agents; D017680:Potassium Compounds; D019279:Resin Cements; C442646:Seal and Protect resin cement; D014100:Toothpastes; C444700:colgate sensitive; C546060:hydrated silica gel-based toothpaste; D012824:Silicic Acid
keywords: Dental practice; Dentinal hypersensitivity; Dentine bonding agent; Desensitising toothpaste; Randomised controlled trial