title: Systemic regulation of adipose metabolism.
abstract: White adipose tissue serves as a critical energy storage depot and endocrine organ. Adipocytes are subject to numerous levels of regulation, including neuronal, endocrine and metabolic. While insulin is the classical endocrine regulator of lipid metabolism in adipose tissue, other important endocrine hormones also control adipose tissue physiology. In this review, we will focus on the contribution of the pituitary in the modulation of adipocyte function, through the direct release of growth hormone as well as via the regulation of the thyroid gland and release of thyroid hormone. This article is part of a Special Issue entitled: Modulation of Adipose Tissue in Health and Disease.
authors.affiliation: The Committee on Molecular Metabolism and Nutrition, University of Chicago, Chicago, IL 60637, USA.
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Carmean
authors.affiliation: The Committee on Molecular Metabolism and Nutrition, University of Chicago, Chicago, IL 60637, USA; Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, University of Chicago, Chicago, IL 60637, USA.
authors.forename: Ronald N
authors.initials: RN
authors.lastname: Cohen
authors.affiliation: The Committee on Molecular Metabolism and Nutrition, University of Chicago, Chicago, IL 60637, USA; Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, University of Chicago, Chicago, IL 60637, USA. Electronic address: mbrady1@uchicago.edu.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Brady
mesh_terms: D017667:Adipocytes / Q000378:metabolism; D052436:Adipose Tissue, White / Q000254:growth & development / Q000378:metabolism*; D004703:Endocrine System / Q000378:metabolism* / Q000502:physiology; D004734:Energy Metabolism; D013006:Growth Hormone / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D050356:Lipid Metabolism / Q000502:physiology; D008066:Lipolysis / Q000502:physiology; D010902:Pituitary Gland / Q000378:metabolism; D013963:Thyroid Hormones / Q000378:metabolism* / Q000502:physiology
chemical_list: D013963:Thyroid Hormones; D013006:Growth Hormone
keywords: Adipocyte; Lipolysis; Pituitary