title: The occurrence or fibrillary glomerulonephritis in patients with diabetes mellitus may not be coincidental: a report of four cases.
abstract: Although clinical presentation of fibrillary glomerulonephritis is similar to most forms of glomerulonephritis, it is usually difficult to make the diagnosis. Clinical manifestations include proteinuria, microscopic haematuria, nephrotic syndrome, and impairment of renal function. A diagnosis of fibrillary glomerulonephritis is only confirmed by renal biopsy and it must comprise electronmicroscopy-verified ultrastructural findings. We report four cases between 45-50 years old with documented type 2 diabetes mellitus (T2DM) and arterial hypertension. All patients were found to have fibrils on kidney biopsy. The differential diagnosis of fibrils in the setting of diabetes mellitus is also discussed.
authors.affiliation: Nephrology Department, Dr. Negrin University Hospital, Las Palmas de Gran Canaria University, Barranco de la Ballena s/n, 35010 Las Palmas de Gran Canaria, Spain.
authors.forename: Fayna
authors.initials: F
authors.lastname: González-Cabrera
authors.forename: Fernando
authors.initials: F
authors.lastname: Henríquez-Palop
authors.forename: Ana
authors.initials: A
authors.lastname: Ramírez-Puga
authors.forename: Raquel
authors.initials: R
authors.lastname: Santana-Estupiñán
authors.forename: Celia
authors.initials: C
authors.lastname: Plaza-Toledano
authors.forename: Gloria
authors.initials: G
authors.lastname: Antón-Pérez
authors.forename: Silvia
authors.initials: S
authors.lastname: Marrero-Robayna
authors.forename: Davinia
authors.initials: D
authors.lastname: Ramírez-Medina
authors.forename: Roberto
authors.initials: R
authors.lastname: Gallego-Samper
authors.forename: Nicanor
authors.initials: N
authors.lastname: Vega-Díaz
authors.forename: Rafael
authors.initials: R
authors.lastname: Camacho-Galan
authors.forename: José C
authors.initials: JC
authors.lastname: Rodríguez-Pérez