title: Molecular epidemiologic source tracking of orally transmitted Chagas disease, Venezuela.
abstract: Oral outbreaks of Chagas disease are increasingly reported in Latin America. The transitory presence of Trypanosoma cruzi parasites within contaminated foods, and the rapid consumption of those foods, precludes precise identification of outbreak origin. We report source attribution for 2 peri-urban oral outbreaks of Chagas disease in Venezuela via high resolution microsatellite typing.
authors.affiliation: Universidad Central de Venezuela Instituto deMedicina Tropical, Caracas, Venezuela.
authors.forename: Maikell
authors.initials: M
authors.lastname: Segovia
authors.forename: Hernán J
authors.initials: HJ
authors.lastname: Carrasco
authors.forename: Clara E
authors.initials: CE
authors.lastname: Martínez
authors.forename: Louisa A
authors.initials: LA
authors.lastname: Messenger
authors.forename: Anaibeth
authors.initials: A
authors.lastname: Nessi
authors.forename: Juan C
authors.initials: JC
authors.lastname: Londoño
authors.forename: Raul
authors.initials: R
authors.lastname: Espinosa
authors.forename: Cinda
authors.initials: C
authors.lastname: Martínez
authors.forename: Mijares
authors.initials: M
authors.lastname: Alfredo
authors.forename: Rafael
authors.initials: R
authors.lastname: Bonfante-Cabarcas
authors.forename: Michael D
authors.initials: MD
authors.lastname: Lewis
authors.forename: Belkisyolé A
authors.initials: BA
authors.lastname: de Noya
authors.forename: Michael A
authors.initials: MA
authors.lastname: Miles
authors.forename: Martin S
authors.initials: MS
authors.lastname: Llewellyn
mesh_terms: D000293:Adolescent; D000328:Adult; D000913:Antibodies, Protozoan / Q000097:blood; D014355:Chagas Disease / Q000097:blood / Q000453:epidemiology* / Q000469:parasitology / Q000635:transmission; D002648:Child; D016000:Cluster Analysis; D016358:Contact Tracing; D016002:Discriminant Analysis; D004196:Disease Outbreaks; D017125:Genes, Protozoan; D006801:Humans; D018895:Microsatellite Repeats; D017720:Molecular Epidemiology; D058889:Molecular Typing; D010802:Phylogeny; D025341:Principal Component Analysis; D014349:Trypanosoma cruzi / Q000235:genetics* / Q000276:immunology; D014687:Venezuela / Q000453:epidemiology
chemical_list: D000913:Antibodies, Protozoan
keywords: Caracas; Chagas disease; Trypanosoma cruzi; Vargas State; Venezuela; molecular epidemiology; oral; orally transmitted; parasites; trypanosome; vector-borne infections; zoonoses