title: Fish and egg specific immunoglobin e in multiple sclerosis patients.
abstract: BACKGROUND
  The effect of nutrition in the course of multiple sclerosis (MS) is a topic of great interest. The present study was aimed to evaluate the immunoglobin E (IgE) against egg and fish in MS patients compared to healthy controls.
  
  
  METHODS
  Between March 2012 and July 2012, 48 MS patients were selected and compared with 48 healthy subjects to assess the frequency of IgE against egg and fish in MS patients compared to healthy control. Fish and Egg specific IgE was determined by Immuno CAP. Sex and the frequency of specific IgE were compared between study groups by Chi-square test.
  
  
  RESULTS
  Total of 96 subjects was assessed (22% male and 78% female). The mean age of the study subjects was 30.8 ± 6.6 years. Mean age of case and control groups was 30.7 (±6.9) versus 30.9 ± 6.3, respectively (P = 0.83). There were no detection of egg and fish specific IgE in serum of MS patients and healthy subjects.
  
  
  CONCLUSIONS
  IgE allergy against fish and egg may be very unlikely to affect MS course.
authors.affiliation: Department of Neurology, Isfahan Neuroscience Research Centre, Isfahan University of Medical Science, Isfahan, Iran.
authors.forename: Fereshteh
authors.initials: F
authors.lastname: Ashtari
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Jamshidi
authors.forename: Raheleh Shokouhi
authors.initials: RS
authors.lastname: Shoormasti
authors.forename: Zahra
authors.initials: Z
authors.lastname: Pourpak
authors.forename: Mojtaba
authors.initials: M
authors.lastname: Akbari
authors.forename: Faiborz
authors.initials: F
authors.lastname: Zandieh
keywords: Allergy; egg; fish; immunoglobin E; multiple sclerosis