title: Assisted reproductive technique outcomes in hypogonadotropic hypogonadism women.
abstract: OBJECTIVE
  To evaluate the outcomes of using in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI cycle) techniques in hypogonadotropic hypogonadism (HH) women and comparing them to women with tubal factor infertility.
  
  
  METHODS
  Retrospective cohort study in Royan Institute, Iran.
  
  
  METHODS
  Data from 81 HH patients treated with IVF/ICSI in the period from early 2009 until the end of 2010 were analyzed and compared with treatment results from 89 patients with tubal factor infertility. Moreover, data from the HH patients were analyzed with respect to the age factor. P value < .05 was considered statistically significant. The main outcome measures were implantation, fertilization, pregnancy, and live birth rates.
  
  
  RESULTS
  Despite a higher fertilization rate and higher number of grade A/B embryos transferred in the tubal factor group, the implantation, pregnancy, and live birth rates were found to be similar between the 2 groups (P=.3, P=.1, P=.1, respectively). When the HH patients were evaluated according to the age factor, no significant difference was found regarding outcome parameters (P=.2).
  
  
  CONCLUSIONS
  HH women that were treated with IVF/ICSI cycles seem to have a sound potential for pregnancy, even in advanced age patients.
authors.affiliation: Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Number 12 East Hafez Avenue, Bani Hashem Street, Resalat Highway, Tehran, Iran. ghafaryf@yahoo.com
authors.forename: Firouzeh
authors.initials: F
authors.lastname: Ghaffari
authors.forename: Arezoo
authors.initials: A
authors.lastname: Arabipoor
authors.forename: Narqes Bagheri
authors.initials: NB
authors.lastname: Lankarani
authors.forename: Zhaleh
authors.initials: Z
authors.lastname: Etminan
authors.forename: Ensieh Shahrokh
authors.initials: ES
authors.lastname: Tehraninejad
mesh_terms: D000328:Adult; D000367:Age Factors; D015331:Cohort Studies; D010064:Embryo Implantation; D005184:Fallopian Tube Diseases / Q000150:complications*; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007006:Hypogonadism / Q000150:complications*; D007247:Infertility, Female / Q000209:etiology; D007492:Iran; D050498:Live Birth / Q000453:epidemiology; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*