title: Prior history of traumatic brain injury among persons in the Traumatic Brain Injury Model Systems National Database.
abstract: OBJECTIVE
  To determine the association between demographic, psychosocial, and injury-related characteristics and traumatic brain injury (TBI) occurring prior to a moderate or severe TBI requiring rehabilitation.
  
  
  METHODS
  Secondary data analysis.
  
  
  METHODS
  TBI Model System inpatient rehabilitation facilities.
  
  
  METHODS
  Persons (N=4464) 1, 2, 5, 10, 15, or 20 years after TBI resulting in participation in the TBI Model System National Database.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  History of TBI prior to the TBI Model System Index injury, pre-Index injury demographic and behavioral characteristics, Index injury characteristics, post-Index injury behavioral health and global outcome.
  
  
  RESULTS
  Twenty percent of the cohort experienced TBIs preceding the TBI Model System Index injury-80% of these were mild and 40% occurred before age 16. Pre- and post-Index injury behavioral issues, especially substance abuse, were highly associated with having had a prior TBI. Greater severity of the pre-Index injury as well as occurrence before age 6 often showed stronger associations. Unexpectedly, pre-Index TBI was associated with less severe Index injuries and better functioning on admission and discharge from rehabilitation.
  
  
  CONCLUSIONS
  Findings suggest that earlier life TBI may have important implications for rehabilitation after subsequent TBI, especially for anticipating behavioral health issues in the chronic stage of recovery. Results provide additional evidence for the potential consequences of early life TBI, even if mild.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Ohio State University, Columbus, OH. Electronic address: corrigan.1@osu.edu.
authors.forename: John D
authors.initials: JD
authors.lastname: Corrigan
authors.forename: Jennifer
authors.initials: J
authors.lastname: Bogner
authors.forename: Dave
authors.initials: D
authors.lastname: Mellick
authors.forename: Tamara
authors.initials: T
authors.lastname: Bushnik
authors.forename: Kristen
authors.initials: K
authors.lastname: Dams-O'Connor
authors.forename: Flora M
authors.initials: FM
authors.lastname: Hammond
authors.forename: Tessa
authors.initials: T
authors.lastname: Hart
authors.forename: Stephanie
authors.initials: S
authors.lastname: Kolakowsky-Hayner
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000437:Alcoholism / Q000150:complications; D001930:Brain Injuries / Q000150:complications* / Q000523:psychology* / Q000534:rehabilitation; D002908:Chronic Disease; D016208:Databases, Factual / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000150:complications*; D008875:Middle Aged; D012047:Rehabilitation Centers; D012959:Socioeconomic Factors; D015599:Trauma Severity Indices; D055815:Young Adult
keywords: Anxiety; BAC; Brain injuries; Craniocerebral trauma; Depression; LOC; OSU TBI-ID; Ohio State University Traumatic Brain Injury Identification Method; Rehabilitation; TBI; TBIMS; Traumatic Brain Injury Model Systems; blood alcohol content; loss of consciousness; traumatic brain injury