title: Collagen functionalized with unsaturated cyclic anhydrides-interactions in solution and solid state.
abstract: Maleic anhydride (CMA) and itaconic anhydride modified collagen (CITA) were prepared as precursors for production of interpenetrated polymer networks (IPN). Calculated values for Huggins coefficient in aqueous diluted and semi-diluted solutions of modified collagen indicated a slightly tendency of aggregation for itaconic anhydride-modified collagen. In semi-diluted solution collagen (Coll) and CMA present slightly differences in the thixotropic behavior, while CITA has a pronounced thixotropic behavior. Flow and oscillatory measurements revealed an elastic behavior of the collagen solutions, pure and modified with MA or ITA, as the storage modulus (G') has always a superior value compared with the loss modulus (G″). The denaturation temperature (Td) of unmodified collagen increased from 34°C to 40°C for CMA and to 39°C for CITA respectively, by formation of covalent bonds that stabilize the triple helix.
authors.affiliation: Department of Natural and Synthetic Polymers, "Gheorghe Asachi", Technical University of Iasi, Faculty of Chemical Engineering and Environmental Protection, Str. D. Mangeron 73, 700050, Iasi, Romania; Normandie Université, France; Université de Rouen, Laboratoire Polymères Biopolymères Surfaces, F-76821, Mont Saint Aignan, France; CNRS UMR 6270 & FR3038, F-76821, Mont Saint Aignan, France.
authors.forename: S
authors.initials: S
authors.lastname: Potorac
authors.forename: M
authors.initials: M
authors.lastname: Popa
authors.forename: L
authors.initials: L
authors.lastname: Picton
authors.forename: V
authors.initials: V
authors.lastname: Dulong
authors.forename: L
authors.initials: L
authors.lastname: Verestiuc
authors.forename: D
authors.initials: D
authors.lastname: Le Cerf
mesh_terms: D000812:Anhydrides / Q000737:chemistry; D003094:Collagen / Q000737:chemistry; D012212:Rheology; D012996:Solutions; D013696:Temperature; D014783:Viscosity
chemical_list: D000812:Anhydrides; D012996:Solutions; D003094:Collagen
keywords: collagen; rheology; temperature