title: Hopping between differentiation states in lung adenocarcinoma.
abstract: The work by Cheung and colleagues, in this issue of Cancer Cell, demonstrates another example of how lineage-specific transcriptional regulators of differentiation, GATA6 and HOPX, can control the fate of lung adenocarcinoma progression.
authors.affiliation: Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA. hideo_watanabe@dfci.harvard.edu
authors.forename: Hideo
authors.initials: H
authors.lastname: Watanabe
authors.forename: Matthew
authors.initials: M
authors.lastname: Meyerson
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000077192:Adenocarcinoma of Lung; D050993:GATA6 Transcription Factor / Q000502:physiology*; D018398:Homeodomain Proteins / Q000502:physiology*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D009362:Neoplasm Metastasis / Q000473:pathology*; D025521:Tumor Suppressor Proteins / Q000502:physiology*
chemical_list: D050993:GATA6 Transcription Factor; C494759:GATA6 protein, human; C476884:HOPX protein, human; D018398:Homeodomain Proteins; D025521:Tumor Suppressor Proteins