title: Endovascular cannulation with a microneedle for central retinal vein occlusion.
abstract: We developed a new surgical treatment in which a microneedle is used for retinal endovascular cannulation to treat eyes with central retinal vein occlusion by flushing thrombus out of the central retinal vein as it passes through the lamina cribrosa. The eyes of 12 consecutive patients (12 eyes) with central retinal vein occlusion were successfully treated using this novel treatment. At 24 weeks after surgery, 9 of 12 eyes had gained more than 15 letters in best-corrected visual acuity, and the mean decrease in central foveal thickness was 271.1 μm. Few complications were observed. The microneedle is stiff and sharp enough to facilitate retinal endovascular cannulation in eyes with central retinal vein occlusion. This new technique is a promising treatment of macular edema due to central retinal vein occlusion.
authors.affiliation: Department of Ophthalmology, Yokohama City University Medical Center, Yokohama City, Japan. kado@med.yokohama-cu.ac.jp
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Kadonosono
authors.forename: Shin
authors.initials: S
authors.lastname: Yamane
authors.forename: Akira
authors.initials: A
authors.lastname: Arakawa
authors.forename: Maiko
authors.initials: M
authors.lastname: Inoue
authors.forename: Tadashi
authors.initials: T
authors.lastname: Yamakawa
authors.forename: Eiichi
authors.initials: E
authors.lastname: Uchio
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Yanagi
authors.forename: Shiro
authors.initials: S
authors.lastname: Amano
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003941:Diagnostic Techniques, Ophthalmological; D057510:Endovascular Procedures / Q000295:instrumentation*; D004867:Equipment Design; D005260:Female; D005584:Fovea Centralis / Q000473:pathology; D006801:Humans; D008269:Macular Edema / Q000209:etiology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D008904:Miniaturization; D009339:Needles; D011446:Prospective Studies; D011677:Punctures; D020127:Recovery of Function; D012170:Retinal Vein Occlusion / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D014792:Visual Acuity