title: Synthesis, physicochemical properties, and in vitro antibacterial screening of palladium(II) complexes derived from thiosemicarbazone.
abstract: A new series of PdII complexes derived from thiosemicarbazone has been synthesized. The synthesized PdII complexes have been characterized on the basis of elemental analyses, FT-IR, ¹H- and ¹³C-NMR, UV/VIS, and thermal studies. A square-planar geometry has been assigned around PdII ions on the basis of results obtained from UV/VIS studies. The thiosemicarbazone ligand and its PdII complexes have been screened against Gram-positive (Bacillus subtilis and Staphylococcus aureus) and Gram-negative (Escherichia coli and Pseudomonas aeruginosa) bacteria in vitro as growth-inhibiting agents, and the results revealed significant antibacterial activities.
authors.affiliation: Department of Chemistry, King Saud University, P.O. Box 2455, Riyadh 11451, KSA. azam_res@yahoo.com
authors.forename: Mohammad
authors.initials: M
authors.lastname: Azam
authors.forename: Ismail
authors.initials: I
authors.lastname: Warad
authors.forename: Saud I
authors.initials: SI
authors.lastname: Al-Resayes
authors.forename: M Rafiq
authors.initials: MR
authors.lastname: Siddiqui
authors.forename: M
authors.initials: M
authors.lastname: Oves
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D056831:Coordination Complexes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D018360:Crystallography, X-Ray; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D010165:Palladium / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013882:Thiosemicarbazones / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D056831:Coordination Complexes; D013882:Thiosemicarbazones; D010165:Palladium