title: Influence of the neuropsychological functions in theory of mind in schizophrenia: the false-belief/deception paradigm.
abstract: The aim of this study was to investigate the influence of neurocognition in a false-belief/deception theory of mind (ToM) task in a sample of patients with schizophrenia. In a cross-sectional study of 43 remitted patients, the implication of neurocognition in first- and second-order ToM stories was analyzed, controlling for clinical symptoms and duration of illness. None of the cognitive factors were associated with the first-order ToM stories. A logistic regression model with high specificity (96.3%) and sensitivity (75%) was obtained in the second-order ToM story "The Burglar," the Information subtest (odds ratio [OR], 0.783; 95% confidence interval [CI], 0.62-0.99; p = 0.04) and the Block Design subtest (OR, 0.89; 95% CI, 0.79-1; p = 0.056) of the Wechsler Adult Intelligence Scale-III being the best predictive factors. Neurocognition was not related to first- or second-order ToM false-belief performance of the patients with schizophrenia. However, an influence of neuropsychological variables in the second-order ToM deception was observed. The clinical implications in the assessment of ToM are discussed.
authors.affiliation: Research Department, Fundació-Universitary Hospital Parc Taulí, Corporació Sanitària i Universitària Parc Taulí, Parc Taulí 1, 08208, Sabadell, Barcelona, Spain. msfernandez@tauli.cat
authors.forename: Sol
authors.initials: S
authors.lastname: Fernandez-Gonzalo
authors.forename: Esther
authors.initials: E
authors.lastname: Pousa
authors.forename: Merce
authors.initials: M
authors.lastname: Jodar
authors.forename: Marc
authors.initials: M
authors.lastname: Turon
authors.forename: Roso
authors.initials: R
authors.lastname: Duño
authors.forename: Diego
authors.initials: D
authors.lastname: Palao
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D009483:Neuropsychological Tests; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D012680:Sensitivity and Specificity; D056345:Theory of Mind / Q000145:classification / Q000502:physiology*; D014888:Wechsler Scales