title: Three-decade metabolic outcome of neonatal gastrectomy and early Roux-en-Y.
abstract: Little information is available about long-term outcomes of major gastric surgery when performed very early in life and adverse consequences in growing children might be expected. In this case, gastrectomy with Roux-en-Y esophagojejunostomy was performed in early childhood. Despite stomach loss, growth velocity paralleled the third percentile for age during development. Maintained on a daily multivitamin and monthly B12 injections, no overt nutritional deficiencies were detected in adulthood. However, dual energy X-ray absorptiometry scan at age 31 revealed that the patient had abnormally low bone mineral density. This case study demonstrates that even after gastrectomy and reconstruction early in life, linear growth can be achieved. However, bone density can be adversely affected, even in the face of normal serum calcium and vitamin D levels.
authors.affiliation: Department of Pediatric and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 2023, Cincinnati, OH, 45229-3039, USA, margaret.stefater@childrens.harvard.edu.
authors.forename: M A
authors.initials: MA
authors.lastname: Stefater
authors.forename: S A
authors.initials: SA
authors.lastname: Xanthakos
authors.forename: J
authors.initials: J
authors.lastname: Johannigman
authors.forename: T H
authors.initials: TH
authors.lastname: Inge
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods; D000328:Adult; D000713:Anastomosis, Roux-en-Y / Q000009:adverse effects* / Q000379:methods; D015992:Body Mass Index; D015519:Bone Density / Q000502:physiology; D002118:Calcium / Q000627:therapeutic use; D019587:Dietary Supplements; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000009:adverse effects* / Q000379:methods; D005756:Gastritis / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D007583:Jejunum / Q000601:surgery; D010024:Osteoporosis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism; D016896:Treatment Outcome; D014805:Vitamin B 12 / Q000627:therapeutic use; D014803:Vitamin B Complex / Q000627:therapeutic use
chemical_list: D014803:Vitamin B Complex; D014805:Vitamin B 12; D002118:Calcium