title: The spectrum of IgG4-related disease in the abdomen and pelvis.
abstract: OBJECTIVE
  IgG4-related disease was not recognized as a specific clinical entity until 2003 when extrapancreatic lesions were reported in patients with autoimmune pancreatitis. IgG4-related disease is characterized by elevated serum IgG4 levels and infiltration of the target organ by IgG4-positive plasma cells. The complete gamut of visceral involvement is still being outlined. The purpose of this article is to highlight the plethora of lesions under the spectrum of IgG4-related disease of the abdomen and pelvis, describe their imaging appearances on multimodality cross-sectional imaging, and discuss the differential diagnoses.
  
  
  CONCLUSIONS
  It is important for radiologists to recognize the multiorgan involvement and few classic features of IgG4-related disease that often tend to simulate malignancy.
authors.affiliation: Department of Abdominal Imaging and Intervention, Massachusetts General Hospital, 55 Fruit St, White 270, Boston, MA 02114, USA. Hedgire.Sandeep@mgh.harvard.edu
authors.forename: Sandeep S
authors.initials: SS
authors.lastname: Hedgire
authors.forename: Shaunagh
authors.initials: S
authors.lastname: McDermott
authors.forename: David
authors.initials: D
authors.lastname: Borczuk
authors.forename: Azadeh
authors.initials: A
authors.lastname: Elmi
authors.forename: Sanjay
authors.initials: S
authors.lastname: Saini
authors.forename: Mukesh G
authors.initials: MG
authors.lastname: Harisinghani
mesh_terms: D001327:Autoimmune Diseases / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D003952:Diagnostic Imaging; D004066:Digestive System Diseases / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood* / Q000276:immunology; D008206:Lymphatic Diseases / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D052801:Male Urogenital Diseases / Q000097:blood / Q000175:diagnosis* / Q000276:immunology
chemical_list: D007074:Immunoglobulin G