title: Effectiveness of a prevention of mother-to-child HIV transmission program in Guangdong province from 2007 to 2010.
abstract: BACKGROUND
  To achieve the goal of United Nations of elimination of new HIV infections, a program of prevention of mother-to-child transmission (PMTCT) was launched in Guangdong province. The objective of this study is to evaluate the effectiveness of the PMTCT program.
  
  
  METHODS
  The retrospective cross-section analysis was conducted using the data of case reported cards of HIV positive mothers and their infants from 2007 to 2010 in Guangdong province, and 108 pairs of eligible subjects were obtained. We described the data and compared the rates of MTCT by various PMTCT interventions respectively.
  
  
  RESULTS
  The overall rate of HIV MTCT was 13.89% (15) among 108 pairs of HIV positive mothers and their infants; 60.19% (65) of the mothers ever received ARVs, 80.56% (87) of infants born to HIV positive mothers ever received ARVs, but 16.67% (18) of the mothers and infants neither received ARVs. Among all the mothers and infants, who both received ARVs, received triple ARVs, mother received ARVs during pregnancy, and both received ARVs and formula feeding showed the lower rates of HIV MTCT, and the rates were 8.06%, 2.50%, 5.77%, and 6.67% respectively. In infants born to HIV positive mother, who received mixed feeding had a higher HIV MTCT up to 60.00%. Delivery mode might not relative to HIV MTCT.
  
  
  CONCLUSIONS
  The interventions of PMTCT program in Guangdong could effectively reduce the rate of HIV MTCT, but the effectiveness of the PMTCT program were heavily cut down by the lower availability of the PMTCT interventions.
authors.affiliation: Department of Epidemiology, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou North Road 1838, Guangzhou 510515, China.
authors.forename: Bing
authors.initials: B
authors.lastname: Li
authors.forename: Qingguo
authors.initials: Q
authors.lastname: Zhao
authors.forename: Xiaozhuang
authors.initials: X
authors.lastname: Zhang
authors.forename: Li
authors.initials: L
authors.lastname: Wu
authors.forename: Tingting
authors.initials: T
authors.lastname: Chen
authors.forename: Zhijiang
authors.initials: Z
authors.lastname: Liang
authors.forename: Longchang
authors.initials: L
authors.lastname: Xu
authors.forename: Shouyi
authors.initials: S
authors.lastname: Yu
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D002681:China; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000517:prevention & control* / Q000635:transmission; D006679:HIV Seropositivity / Q000175:diagnosis; D006801:Humans; D007223:Infant; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control* / Q000706:statistics & numerical data; D011247:Pregnancy; D011256:Pregnancy Outcome; D011314:Preventive Health Services / Q000379:methods*; D015397:Program Evaluation; D012189:Retrospective Studies; D012923:Social Class; D055815:Young Adult
chemical_list: D044966:Anti-Retroviral Agents