title: Septic shock caused by Klebsiella pneumoniae carbapenemase-producing Enterobacter gergoviae in a neutropenic patient with leukemia.
abstract: We present the first reported infection caused by Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacter gergoviae. The patient had leukemia and neutropenia and died of septic shock from KPC-producing E. gergoviae bacteremia. The emergence of KPCs in additional species of Enterobacteriaceae is alarming and may disproportionately affect patients with hematologic malignancies.
authors.affiliation: Transplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Weill Cornell Medical College, New York, New York, USA. mjs9012@med.cornell.edu
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Satlin
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Jenkins
authors.forename: Liang
authors.initials: L
authors.lastname: Chen
authors.forename: David
authors.initials: D
authors.lastname: Helfgott
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Feldman
authors.forename: Barry N
authors.initials: BN
authors.lastname: Kreiswirth
authors.forename: Audrey N
authors.initials: AN
authors.lastname: Schuetz
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000378:metabolism*; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D007938:Leukemia / Q000150:complications*; D008297:Male; D008826:Microbial Sensitivity Tests; D009503:Neutropenia / Q000150:complications*; D012772:Shock, Septic / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase