title: [Influence of a genetic component on the propensity of dust-exposed workers to visceropathies (on the pattern of detecting polymorphisms in the transmembrane conductance regulatory protein CFTR gene)].
abstract: Obtained results of molecular genetics testing of workers' groups exposed to dust show the elimination of carriers of defective variants in the CFTR gene among workers exposed to dust. We can establish a fact that in spite of law frequency of detected major mutations of the CFTR gene in explored selections they have big importance as individual factors in the stage of preliminary medical examinations in terms of prediction of possible occupational development risk and progression of productionally mediated visceropathies and diseases, as well as a conscious choice of occupation by an individual.
authors.forename: S A
authors.initials: SA
authors.lastname: Peskov
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Bravve
authors.forename: A B
authors.initials: AB
authors.lastname: Maslennikov
authors.forename: E L
authors.initials: EL
authors.lastname: Poteriaeva
authors.forename: E L
authors.initials: EL
authors.lastname: Smirnova
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Poliakov
authors.forename: N G
authors.initials: NG
authors.lastname: Nikiforova
mesh_terms: D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D015415:Biomarkers; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics*; D004391:Dust; D005787:Gene Frequency / Q000235:genetics; D020022:Genetic Predisposition to Disease; D006801:Humans; D008171:Lung Diseases / Q000209:etiology / Q000235:genetics; D008297:Male; D008452:Maximum Allowable Concentration; D008875:Middle Aged; D009154:Mutation / Q000235:genetics; D009784:Occupational Diseases / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics; D012307:Risk Factors; D012800:Siberia / Q000453:epidemiology
chemical_list: D000395:Air Pollutants, Occupational; D015415:Biomarkers; D004391:Dust; D019005:Cystic Fibrosis Transmembrane Conductance Regulator