title: Simple synthesis of pyrrolo[3,2-e]indole-1-carbonitriles.
abstract: Alkylation of 5-nitroindol-4-ylacetonitriles with ethyl chloroacetate, α-halomethyl ketones, and chloroacetonitrile followed by a treatment of the products with chlorotrimethylsilane in the presence of DBU gives 1-cyanopyrrolo[3,2-e]indoles substituted in position 2 with electron-withdrawing groups.
authors.affiliation: Institute of Organic Chemistry, Polish Academy of Sciences, ul. Kasprzaka 44/52, POBox 58, 01-224 Warszawa, Poland, ; Department of Chemistry, Warsaw University of Technology, ul. Noakowskiego 3, 00-664 Warszawa, Poland.
authors.forename: Adam
authors.initials: A
authors.lastname: Trawczyński
authors.forename: Robert
authors.initials: R
authors.lastname: Bujok
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Wróbel
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Wojciechowski
keywords: alkylation; ketones; nitriles; pyrroloindole; reduction; trimethylchlorosilane