title: [Comparison study of endobronchial ultrasound-guided transbronchial needle aspiration and transbronchial needle aspiration for the diagnosis of hilar and mediastinal lesions].
abstract: OBJECTIVE
  To compare the values of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and TBNA for the diagnosis of hilar and mediastinal lesions.
  
  
  METHODS
  The clinical data of 100 patients who underwent EBUS-TBNA (n=50) and TBNA (n=50) between January 2010 and May 2011 were retrospectively reviewed, and the results and complications were recorded.
  
  
  RESULTS
  A total of 121 lesions in the 100 patients were evaluated, the sample yeilds of EBUS-TBNA and TBNA were 90.6% and 78.9% and the diagnostic accuracy rates in the two groups were 90.0% and 72.0%(P=0.022), respectively. No major complications happened. The sensitivity, specificity and accuracy of EBUS-TBNA were higher and the complication rate was not increased as compared with TBNA.
  
  
  CONCLUSIONS
  EBUS-TBNA has a higher diagnostic yield for the evaluation of hilar and mediastinal lesions.
authors.affiliation: Peking University Cancer Hospital & Institute, Beijing, China. wuqi@bycancer.org
authors.forename: Qi
authors.initials: Q
authors.lastname: Wu
authors.forename: Chang-qi
authors.initials: CQ
authors.lastname: Cao
authors.forename: Shi-jie
authors.initials: SJ
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Yan
authors.forename: Xiang-ju
authors.initials: XJ
authors.lastname: Li
authors.forename: Shi
authors.initials: S
authors.lastname: Yan
authors.forename: Nan
authors.initials: N
authors.lastname: Wu
authors.forename: Ji-chang
authors.initials: JC
authors.lastname: Zhang
mesh_terms: D044963:Biopsy, Fine-Needle / Q000379:methods*; D001999:Bronchoscopy / Q000379:methods*; D006801:Humans; D008477:Mediastinal Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008482:Mediastinum / Q000473:pathology; D012680:Sensitivity and Specificity; D014463:Ultrasonography / Q000379:methods*