title: Acute lymphoblastic leukemia with treatment--naive Fanconi anemia.
abstract: Fanconi anemia is known to have a predisposition to cancer, mostly associated with acute myeloid leukemia. We report an eight year old girl with treatment and naive FA who developed acute lymphoblastic leukemia. She was initiated on chemotherapy but she failed to respond to treatment and died during induction phase of chemotherapy. While this association may be coincidental but possibility of transition of Fanconi anemia to ALL should be considered in view of high predisposition to cancer in this disorder.
authors.affiliation: Department of Pediatrics, Armed Forces Medical College, Pune, Maharashtra, India 411040.
authors.forename: Ankit
authors.initials: A
authors.lastname: Shah
authors.forename: Biju M
authors.initials: BM
authors.lastname: John
authors.forename: Vishal
authors.initials: V
authors.lastname: Sondhi
mesh_terms: D002648:Child; D005199:Fanconi Anemia / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood* / Q000188:drug therapy*