title: Aqueous reductive amination using a dendritic metal catalyst in a dialysis bag.
abstract: Water-soluble dendritic iridium catalysts were synthesized by attaching a reactive metal complex to DAB-Am dendrimers via an adapted asymmetric bipyridine ligand. These dendritic catalysts were applied in the aqueous reductive amination of valine while contained in a dialysis bag. Comparable conversions were observed as for the noncompartmentalized counterparts, albeit with somewhat longer reaction times. These results clearly show that the encapsulated catalyst system is suitable to successfully drive a complex reaction mixture with various equilibrium reactions to completion.
authors.affiliation: Radboud University Nijmegen, Institute for Molecules and Materials, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.
authors.forename: Jorgen S
authors.initials: JS
authors.lastname: Willemsen
authors.forename: Jan C M
authors.initials: JC
authors.lastname: van Hest
authors.forename: Floris P J T
authors.initials: FP
authors.lastname: Rutjes
keywords: aqueous reductive amination; cascade catalysis; compartmentalization; dendritic catalysts; dialysis