title: Association between metabolic syndrome and gallbladder polyps in healthy Korean adults.
abstract: The goal of this study was to evaluate the association between gallbladder (GB) polyps and metabolic syndrome. A total of 5,685 healthy subjects were included, and 485 of these subjects had GB polyps and 744 had metabolic syndrome. In this study, metabolic syndrome was diagnosed according to standards suggested by the AHA/NHLBI ATP III 2005, and abdominal obesity (≥ 90 cm in men and ≥ 85 cm in women for Korean) was diagnosed according to standards set forth by the Korean Society for Study of Obesity. Biphasic logistic regression adjusted for age and gender was used to evaluate the association between metabolic syndrome and GB polyps. Subjects who were male (OR, 1.493; 95% CI, 1.11-2.00) and hepatitis B suface Ag (HBsAg) positive (OR, 1.591; 95% CI, 1.06-2.38) were significantly more likely to have GB polyps. The metabolic syndrome group had a higher risk of GB polyps (OR, 1.315; 95% CI, 1.01-1.69) than the group without metabolic syndrome. In conclusion, subjects who were HBsAg positive and male appear to be associated with the risk of GB polyps. The presence of metabolic syndrome also appears to be associated with the risk of GB polyps in Koreans.
authors.affiliation: Department of Family Medicine, Ewha Womans University College of Medicine, Mokdong Hospital, Seoul, Korea.
authors.forename: Eun Jung
authors.initials: EJ
authors.lastname: Park
authors.forename: Hong Soo
authors.initials: HS
authors.lastname: Lee
authors.forename: Sang Hwa
authors.initials: SH
authors.lastname: Lee
authors.forename: Hye Jin
authors.initials: HJ
authors.lastname: Chun
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Kim
authors.forename: Yu Kyung
authors.initials: YK
authors.lastname: Choi
authors.forename: Hee Jeong
authors.initials: HJ
authors.lastname: Ryu
authors.forename: Kyung Won
authors.initials: KW
authors.lastname: Shim
mesh_terms: D000328:Adult; D000367:Age Factors; D044466:Asian People; D005260:Female; D005705:Gallbladder Diseases / Q000175:diagnosis* / Q000209:etiology; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006801:Humans; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000175:diagnosis*; D008875:Middle Aged; D016017:Odds Ratio; D056910:Republic of Korea; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors
chemical_list: D006514:Hepatitis B Surface Antigens
keywords: GB Polyp; Metabolic Syndrome; Risk Factors