title: Function of PPR proteins in plastid gene expression.
abstract: PPR proteins form a huge family in flowering plants and are involved in RNA maturation in plastids and mitochondria. These proteins are sequence-specific RNA-binding proteins that recruit the machinery of RNA processing. We summarize progress in the research on the functional mechanisms of divergent RNA maturation and on the mechanism by which RNA sequences are recognized. We further focus on two topics. RNA editing is an enigmatic process of RNA maturation in organelles, in which members of the PLS subfamily contribute to target site recognition. As the first topic, we speculate on why the PLS subfamily was selected by the RNA editing machinery. Second, we discuss how the regulation of plastid gene expression contributes to efficient photosynthesis. Although the molecular functions of PPR proteins have been studied extensively, information on the physiological significance of regulation by these proteins remains very limited.
authors.affiliation: Graduate School of Science; Kyoto University; Kyoto, Japan.
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Shikanai
authors.affiliation: Graduate School of Science; Kyoto University; Kyoto, Japan.
authors.forename: Sota
authors.initials: S
authors.lastname: Fujii
mesh_terms: D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism; D002736:Chloroplasts / Q000235:genetics; D018506:Gene Expression Regulation, Plant; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism; D009154:Mutation; D015388:Organelles / Q000235:genetics / Q000378:metabolism; D010788:Photosynthesis / Q000235:genetics; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism; D018087:Plastids / Q000235:genetics*; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D017393:RNA Editing; D018749:RNA, Plant / Q000378:metabolism; D016601:RNA-Binding Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; C518087:CRR3 protein, Arabidopsis; C583236:CRR4 protein, Arabidopsis; D002352:Carrier Proteins; D008565:Membrane Proteins; C587935:PGR3 protein, Arabidopsis; D010940:Plant Proteins; D018749:RNA, Plant; D016601:RNA-Binding Proteins
keywords: PPR; RNA; RNA editing; chloroplast; photosynthesis