title: Over-activation in bilateral superior temporal gyrus correlated with subsequent forgetting effect of Chinese words.
abstract: We evaluated the subsequent memory and forgotten effects for Chinese using event-related fMRI. Sixteen normal subjects were recruited and performing incidental memory tasks where semantic decision was required during memory encoding. Consistent with previous studies, our results showed bilateral frontal regions as the main locus for the subsequent memory effect. However, contrast between miss and hit responses revealed larger activation in bilateral superior temporal gyrus. We proposed that larger activation in the superior temporal gyrus may reflect alteration of self-monitoring process which resulted in unsuccessful memory encoding for the miss items.
authors.affiliation: Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan.
authors.forename: Tzu-Ching
authors.initials: TC
authors.lastname: Chen
authors.forename: Wen-Jui
authors.initials: WJ
authors.lastname: Kuo
authors.forename: Ming-Chang
authors.initials: MC
authors.lastname: Chiang
authors.forename: Yi-Jhan
authors.initials: YJ
authors.lastname: Tseng
authors.forename: Yung-Yang
authors.initials: YY
authors.lastname: Lin
mesh_terms: D000328:Adult; D044466:Asian People; D001931:Brain Mapping; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D007802:Language; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory / Q000502:physiology*; D012660:Semantics; D013702:Temporal Lobe / Q000502:physiology*; D055815:Young Adult
keywords: BA; BOLD; Brodmann area; Chinese; Forgotten effect; Functional magnetic resonance imaging (fMRI); MNI; Memory; Montreal Neurological Institute; STG; Superior temporal gyrus; blood-oxygen-level-dependent; fMRI; functional magnetic resonance imaging; superior temporal gyrus