title: Acanthosis nigricans associated with an adrenocortical tumor in a pediatric patient.
abstract: Malignant acanthosis nigricans (AN) is a rare paraneoplastic syndrome seen primarily in adults with an underlying diagnosis of gastrointestinal adenocarcinoma. Malignant AN is characterized by hyperpigmentation and velvety hyperplasia of the epidermis. This condition is generally not associated with tumors in pediatric populations or in the adrenal gland. We present a case of malignant AN in a pediatric patient with a nonmalignant, functional adrenocortical tumor.
authors.affiliation: Department of Pediatrics, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, 3535 Market Street, Room 1562, Philadelphia, PA 19104, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Isaacoff
authors.forename: Filippina Filia
authors.initials: FF
authors.lastname: Dimitriadi
authors.forename: Frank
authors.initials: F
authors.lastname: Barrows
authors.forename: Bruce
authors.initials: B
authors.lastname: Pawel
authors.forename: Peter
authors.initials: P
authors.lastname: Mattei
authors.forename: Sogol
authors.initials: S
authors.lastname: Mostoufi-Moab