title: Stability of monacolin K and citrinin and biochemical characterization of red-koji vinegar during fermentation.
abstract: Red-koji vinegar is a Monascus -involved and acetic acid fermentation-derived traditional product, in which the presence of monacolin K and citrinin has attracted public attention. In this study, red-koji wine was prepared as the substrate and artificially supplemented with monacolin K and citrinin and subjected to vinegar fermentation with Acetobacter starter. After 30 days of fermentation, 43.0 and 98.1% of the initial supplements of monacolin K and citrinin were decreased, respectively. During fermentation, acetic acid contents increased, accompanied by decreases of ethanol and lactic acid contents and pH values. The contents of free amino acids increased while the contents of other organic acids, including fumaric acid, citric acid, succinic acid, and tartaric acid, changed limitedly. Besides, increased levels of total phenolics in accordance with increased antioxidative potency, α,α-diphenyl-β-picrylhydrazyl scavenging, and xanthine oxidase inhibitory (XOI) activities were detected. It is of merit that most citrinin was eliminated and >50% of the monacolin K was retained; contents of free amino acids and total phenolics along with antioxidant and XOI activities of the red-koji vinegar were increased after fermentation.
authors.affiliation: Department of Microbiology, Immunology and Biopharmaceuticals, National Chiayi University, Chiayi 60004, Taiwan, Republic of China.
authors.forename: Chia-Wen
authors.initials: CW
authors.lastname: Hsieh
authors.forename: Yi-Ru
authors.initials: YR
authors.lastname: Lu
authors.forename: Shu-Mei
authors.initials: SM
authors.lastname: Lin
authors.forename: Tzu-Yuan
authors.initials: TY
authors.lastname: Lai
authors.forename: Robin Y-Y
authors.initials: RY
authors.lastname: Chiou
mesh_terms: D019342:Acetic Acid / Q000032:analysis* / Q000378:metabolism; D000091:Acetobacter / Q000378:metabolism*; D000975:Antioxidants / Q000032:analysis / Q000378:metabolism; D002953:Citrinin / Q000737:chemistry* / Q000378:metabolism; D000431:Ethanol / Q000032:analysis / Q000378:metabolism; D005285:Fermentation; D008148:Lovastatin / Q000737:chemistry* / Q000378:metabolism; D032741:Monascus / Q000378:metabolism; D012275:Oryza / Q000737:chemistry / Q000378:metabolism / Q000382:microbiology*; D014920:Wine / Q000032:analysis* / Q000382:microbiology
chemical_list: D000975:Antioxidants; D000431:Ethanol; D002953:Citrinin; D008148:Lovastatin; D019342:Acetic Acid