title: Campylobacter infection after prosthetic joint surgery.
abstract: Few cases of Campylobacter prosthetic joint infection (PJI) have been reported so far. We describe the demographic characteristics, underlying conditions, clinical features, treatment, and outcome of 8 patients with Campylobacter PJI in our hospital. All strains were confirmed at the French National Reference Center for Campylobacter and Helicobacter. Seven patients were infected with C. fetus and 1 with C. jejuni. Most patients were elderly and immunocompromised. Four had bacteremia, one of these with a pacemaker endocarditis. All the patients received at least 3 months of antibiotic treatment and 6 were treated surgically. The outcome was favorable at 2 years of follow-up in all except for 1 patient. Campylobacter PJI cases are rare but likely to become more frequent. C. fetus bacteremia should motivate physicians to look for a secondary localization such as a Campylobacter PJI.
authors.affiliation: Service d'Orthopédie, Groupe Hospitalier Diaconesses Croix Saint Simon, Paris, France. virginie.prendki@gmail.com
authors.forename: Virginie
authors.initials: V
authors.lastname: Prendki
authors.forename: Simon
authors.initials: S
authors.lastname: Marmor
authors.forename: Valérie
authors.initials: V
authors.lastname: Zeller
authors.forename: Luc
authors.initials: L
authors.lastname: Lhotellier
authors.forename: Francis
authors.initials: F
authors.lastname: Mégraud
authors.forename: Nicole
authors.initials: N
authors.lastname: Desplaces
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D002167:Campylobacter / Q000187:drug effects / Q000302:isolation & purification*; D002169:Campylobacter Infections / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology* / Q000601:surgery; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents