title: [Last resort surgical management of postradiation urinary cystitis after external beam radiation for prostate cancer: a monocentric analysis].
abstract: OBJECTIVE
  To assess functional outcomes obtained after surgical management of post-radiation urinary incontinence after prostate cancer.
  
  
  METHODS
  A retrospective review of the data from patients treated in our centre between September 2004 and February 2012 by surgery for vesicosphincteric injuries after prostatic external beam radiation therapy was performed.
  
  
  RESULTS
  A total of seven men with a median age of 70 years ± 4.1 were included. Mean follow-up was 32.3 months ± 29 (3-86). All patients underwent a partial cystectomy and augmentation enterocystoplasty. The vesicocutaneous fistula rate was 33% occurring within a mean time of 18.5 days ± 2.1 (17-20). The mean length of urinary catheter and hospital stay were respectively 16 days ± 8.4 (12-35) and 18 days ± 7.8 (13-37). Five patients underwent asynchronous insertion of artificial urinary sphincter. The success rate of partial cystectomy and augmentation enterocystoplasty with asynchronous implantation of artificial urinary sphincter to treat post-radiation urinary incontinence was 71.5%. The median time between partial cystectomy and augmentation enterocystoplasty and artificial urinary sphincter implantation was 27.6months ± 26.4 (7-72).
  
  
  CONCLUSIONS
  Surgical management of post-radiation urinary cystitis offers good functional outcomes albeit its morbidity is not negligible. It should be proposed only in expert surgical centres.
authors.affiliation: Service d'Urologie,Hôpital Pitié-Salpêtrière, Assistance publique-Hôpitaux de Paris, 47-83, boulevard de l'Hôpital, 75013 Paris, France.
authors.forename: T
authors.initials: T
authors.lastname: Seisen
authors.forename: M
authors.initials: M
authors.lastname: Rouprêt
authors.forename: V
authors.initials: V
authors.lastname: Phé
authors.forename: P-O
authors.initials: PO
authors.lastname: Bosset
authors.forename: J
authors.initials: J
authors.lastname: Parra
authors.forename: S J
authors.initials: SJ
authors.lastname: Drouin
authors.forename: J-M
authors.initials: JM
authors.lastname: Simon
authors.forename: E
authors.initials: E
authors.lastname: Chartier-Kastler
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy* / Q000601:surgery; D000368:Aged; D000714:Anastomosis, Surgical; D003131:Combined Modality Therapy; D015653:Cystectomy / Q000379:methods; D003556:Cystitis / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007082:Ileum / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy; D011183:Postoperative Complications / Q000209:etiology; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D011832:Radiation Injuries / Q000209:etiology / Q000601:surgery*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D020266:Radiotherapy, Conformal / Q000009:adverse effects*; D012189:Retrospective Studies; D016879:Salvage Therapy / Q000009:adverse effects; D001743:Urinary Bladder / Q000528:radiation effects / Q000601:surgery*; D014549:Urinary Incontinence / Q000209:etiology / Q000601:surgery*; D016741:Urinary Sphincter, Artificial
keywords: AUS; Artificial urinary sphincter; Augmentation enterocystoplasty; Bladder; CPEA; Chronic; Chronique; Cystectomie partielle; Enterocystoplastie d’agrandissement; Incontinence urinaire; PCAE; Partial cystectomy; SUA; Sphincter urinaire artificiel; Urinary incontinence; Vessie