title: Physical models of mesoderm invagination in Drosophila embryo.
abstract: The invagination of the mesoderm in the Drosophila melanogaster embryo is an intensely studied example of epithelial folding. Several theoretical studies have explored the conditions and mechanisms needed to reproduce the formation of the invagination in silico. Here we discuss the aspects of epithelial folding captured by these studies, and compare the questions addressed, the approaches used, and the answers provided.
authors.affiliation: European Molecular Biology Laboratory Heidelberg, Heidelberg, Germany.
authors.forename: Matteo
authors.initials: M
authors.lastname: Rauzi
authors.forename: Ana
authors.initials: A
authors.lastname: Hočevar Brezavšček
authors.forename: Primož
authors.initials: P
authors.lastname: Ziherl
authors.forename: Maria
authors.initials: M
authors.lastname: Leptin
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D055592:Biophysical Phenomena; D004331:Drosophila melanogaster / Q000196:embryology*; D004625:Embryo, Nonmammalian / Q000166:cytology* / Q000502:physiology; D008648:Mesoderm / Q000166:cytology* / Q000502:physiology; D008954:Models, Biological