title: Effects of high vs. moderate exercise intensity during interval training on lipids and adiponectin levels in obese young females.
abstract: OBJECTIVE
  We investigate the effects of 12-week interval training of moderate- or high-intensity exercise on blood lipids and plasma levels of adiponectin.
  
  
  METHODS
  Thirty-four obese adolescent females [age = 15.9 ± 0.3 years; BMI and BMI-Z-score = 30.8 ± 1.6 kg/m(2) and 3 ± 0.3, respectively], were randomized to high-intensity interval training (HIIT, n = 11), moderate-intensity interval training (MIIT, n = 11), or a control group (CG, n = 12). Maximal oxygen uptake ([Formula: see text]), maximal aerobic speed (MAS), plasma lipids and adiponectin levels were measured in all subjects before and after training.
  
  
  RESULTS
  Following the training program, in both training groups, body mass, BMI-Z-score, and percentage body fat (% BF) decreased, while [Formula: see text] and MAS increased. Low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and adiponectin levels were positively altered (-12.6 and -7.4 %; 6.3 and 8.0 %; 35.8 and 16.2 %; high to moderate training program, respectively). Waist circumference, triglyceride and total cholesterol decreased only in HIIT group (-3.5; -5.3 and -7.0 %, respectively, in all P < 0.05). Significant decrease in the usual index of insulin resistance (HOMA-IR) occurred in HIIT and MIIT groups (-29.2 ± 5.3 and -18.4 ± 8.6 %, respectively; P < 0.01).
  
  
  CONCLUSIONS
  The results show that HIIT positively changes blood lipids and adiponectin variables in obese adolescent girls, resulting in improved insulin sensitivity, as attested by a lower HOMA-IR, and achieving better results compared to moderate-intensity exercise.
authors.affiliation: Department of Biological Sciences, Faculty of Science of Tunis, University Tunis el Manar, Tunis, Tunisia, ghazi_racil@yahoo.fr.
authors.forename: G
authors.initials: G
authors.lastname: Racil
authors.forename: O
authors.initials: O
authors.lastname: Ben Ounis
authors.forename: O
authors.initials: O
authors.lastname: Hammouda
authors.forename: A
authors.initials: A
authors.lastname: Kallel
authors.forename: H
authors.initials: H
authors.lastname: Zouhal
authors.forename: K
authors.initials: K
authors.lastname: Chamari
authors.forename: M
authors.initials: M
authors.lastname: Amri
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000293:Adolescent; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D009765:Obesity / Q000097:blood*; D012420:Running
chemical_list: D052242:Adiponectin; D008055:Lipids