title: Microphyllandiolide, a new diterpene with an unprecedented skeleton from Salvia microphylla.
abstract: Microphyllandiolide (1), an unprecedented rearranged clerodane-type diterpene with a 9/3 bicyclic ring system, was isolated from the aerial parts of Salvia microphylla Kunth. Its structure was elucidated by analysis of its spectroscopic data and confirmed by single crystal X-ray diffraction analysis. A possible biogenesis for microphyllandiolide (1) is proposed.
authors.affiliation: Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Coyoacán, México D. F. 04510, México.
authors.forename: Elihú
authors.initials: E
authors.lastname: Bautista
authors.forename: Rubén Alfredo
authors.initials: RA
authors.lastname: Toscano
authors.forename: Alfredo
authors.initials: A
authors.lastname: Ortega
mesh_terms: D018360:Crystallography, X-Ray; D045785:Diterpenes, Clerodane / Q000138:chemical synthesis* / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D027544:Salvia / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D045785:Diterpenes, Clerodane; C585250:microphyllandiolide