title: Diffuse lung disease in children: summary of a scientific conference.
abstract: A multi-disciplinary scientific conference focused on diffuse and interstitial lung diseases in children was held in La Jolla, CA in June 2012. The conference brought together clinicians (including Pediatric and Adult Pulmonologists, Neonatologists, Pathologists, and Radiologists), clinical researchers, basic scientists, government agency representatives, patient advocates, as well as children affected by diffuse lung disease (DLD) and their families, to review recent scientific developments and emerging concepts in the pathophysiology of childhood DLD. Invited speakers discussed translational approaches, including genetics and proteomics, epigenetics and epigenomics, models of DLD, including animal models and induced pluripotent stem cells, and regenerative medicine approaches. The presentations of the invited speakers are summarized here.
authors.affiliation: Washington University School of Medicine, St. Louis Children's Hospital, St. Louis, Missouri.
authors.forename: Aaron
authors.initials: A
authors.lastname: Hamvas
authors.forename: Robin
authors.initials: R
authors.lastname: Deterding
authors.forename: William E
authors.initials: WE
authors.lastname: Balch
authors.forename: David A
authors.initials: DA
authors.lastname: Schwartz
authors.forename: Kurt H
authors.initials: KH
authors.lastname: Albertine
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Whitsett
authors.forename: Wellington V
authors.initials: WV
authors.lastname: Cardoso
authors.forename: Darrell N
authors.initials: DN
authors.lastname: Kotton
authors.forename: Stella
authors.initials: S
authors.lastname: Kourembanas
authors.forename: James S
authors.initials: JS
authors.lastname: Hagood
mesh_terms: D000818:Animals; D002648:Child; D003226:Congresses as Topic; D019175:DNA Methylation; D004195:Disease Models, Animal; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000235:genetics / Q000628:therapy; D029424:Pulmonary Disease, Chronic Obstructive / Q000235:genetics; D011663:Pulmonary Surfactants / Q000378:metabolism; D033581:Stem Cell Transplantation
chemical_list: D011663:Pulmonary Surfactants
keywords: childhood interstitial lung disease; diffuse lung disease; epigenetics; genetics; stem cell