title: The association of ankle brachial index with left ventricular hypertrophy and left ventricular mass index: the Dong-gu study.
abstract: BACKGROUND
  To investigate the association between ankle-brachial index (ABI), left ventricular hypertrophy (LVH) and left ventricular mass index (LVMI) in a general population.
  
  
  METHODS
  The study population consisted of 8,246 people aged 50 years and older who participated in the baseline survey of the Dong-gu Study conducted in Korea between 2007 and 2010. Trained research technicians measured LV mass using mode M ultrasound echocardiography and ABI using an oscillometric method.
  
  
  RESULTS
  After adjustment for risk factors and common carotid artery intima-media thickness (CCA-IMT) and the number of plaques, higher ABIs (1.10 1.19, 1.20 - 1.29, and ≥ 1.30) were significantly and linearly associated with high LVMI (1.10 - 1.19 ABI: β, 3.33; 95 % CI, 1.72 - 4.93; 1.20 - 1.29 ABI: β, 6.51; 95 % CI, 4.02 - 9.00; ≥ 1.30 ABI: β, 14.83; 95 % CI, 6.18 - 23.48). An ABI of 1.10 - 1.19 and 1.20 - 1.29 ABI was significantly associated with LVH (1.10 - 1.19 ABI: OR, 1.35; 95 % CI, 1.19 - 1.53; 1.20 - 1.29 ABI: OR, 1.59; 95 % CI, 1.31 - 1.92) and ABI ≥ 1.30 was marginally associated with LVH (OR, 1.73; 95 % CI, 0.93 - 3.22, p = 0.078).
  
  
  CONCLUSIONS
  After adjustment for other cardiovascular variables and CCA-IMT and the number of plaques, higher ABIs are associated with LVH and LVMI in Koreans aged 50 years and older.
authors.affiliation: Department of Preventive Medicine, Chosun University Medical School, Gwangju, Republic of Korea.
authors.forename: Seong-Woo
authors.initials: SW
authors.lastname: Choi
authors.forename: Hye-Yeon
authors.initials: HY
authors.lastname: Kim
authors.forename: Hye-Ran
authors.initials: HR
authors.lastname: Ahn
authors.forename: Young-Hoon
authors.initials: YH
authors.lastname: Lee
authors.forename: Sun-Seog
authors.initials: SS
authors.lastname: Kweon
authors.forename: Jin-Su
authors.initials: JS
authors.lastname: Choi
authors.forename: Jung-Ae
authors.initials: JA
authors.lastname: Rhee
authors.forename: Hae-Sung
authors.initials: HS
authors.lastname: Nam
authors.forename: Seul-Ki
authors.initials: SK
authors.lastname: Jeong
authors.forename: Kyeong-Soo
authors.initials: KS
authors.lastname: Park
authors.forename: So-Yeon
authors.initials: SY
authors.lastname: Ryu
authors.forename: Min-Ho
authors.initials: MH
authors.lastname: Shin
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D055109:Ankle Brachial Index; D002339:Carotid Arteries / Q000000981:diagnostic imaging*; D002340:Carotid Artery Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology; D059168:Carotid Intima-Media Thickness; D016009:Chi-Square Distribution; D003430:Cross-Sectional Studies; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D058226:Plaque, Atherosclerotic; D011237:Predictive Value of Tests; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology