title: Enantioselective total syntheses of pygmaeocins B and C.
abstract: The first enantioselective total syntheses of pygmaeocins B and C have been accomplished using an efficient and highly diastereoselective intramolecular Heck cyclization for the construction of a quaternary stereogenic center and the functionalized A-ring of the natural products as the key step.
authors.affiliation: Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Sho-machi, Tokushima, 770-8505, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Obase
authors.forename: Akihito
authors.initials: A
authors.lastname: Kageyama
authors.forename: Yuki
authors.initials: Y
authors.lastname: Manabe
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Ozawa
authors.forename: Takaaki
authors.initials: T
authors.lastname: Araki
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Yokoe
authors.forename: Makoto
authors.initials: M
authors.lastname: Kanematsu
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yoshida
authors.forename: Kozo
authors.initials: K
authors.lastname: Shishido
mesh_terms: D001688:Biological Products / Q000737:chemistry*; D003500:Cyclization; D004224:Diterpenes / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013237:Stereoisomerism
chemical_list: D001688:Biological Products; D004224:Diterpenes; C586053:pygmaeocin B