title: Fit and motivated: outcome predictors in patients starting a program for lifestyle change.
abstract: BACKGROUND
  In previous pilot studies we have demonstrated that the Treatment Motivation and Readiness Test (TRE-MORE) is capable of predicting the outcome of obesity therapy and that a higher muscle mass (MM) is associated with a greater weight loss. Purposes of the present study were: to confirm the predictive value of TRE-MORE scores and MM, using a standardized non-pharmacologic intervention for weight loss; to explore the relationship between TRE-MORE and MM; to discriminate predictors of attendance from predictors of final therapeutic success.
  
  
  METHODS
  A consecutive series of 331 patients was enrolled and addressed to a standardized treatment protocol.
  
  
  RESULTS
  Mean weight loss at 6 months was -5.03%. Among participants, 48.7% lost at least 5% initial body weight after 6 months and had significantly higher TRE-MORE total scores and MM. Weight loss was significantly associated with baseline MM, TRE-MORE-3, and a lower number of previous diets. Significantly lower TRE-MORE-3 scores were associated with drop-out.
  
  
  CONCLUSIONS
  The present study confirms that therapeutic success is predicted by TRE-MORE scores and, independently from these, by estimated MM (after adjustment for BMI). TRE-MORE total score is a predictor of failure, but not of attendance, whereas drop-out patients showed a lower score only in TREMORE-3 subscale which investigates lifestyle habits.
authors.affiliation: Endocrinology Unit, AOU Careggi, Florence, Italy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Cresci
authors.forename: Giovanni
authors.initials: G
authors.lastname: Castellini
authors.forename: Laura
authors.initials: L
authors.lastname: Pala
authors.forename: Michela
authors.initials: M
authors.lastname: Bigiarini
authors.forename: Ester
authors.initials: E
authors.lastname: Romoli
authors.forename: Roberta
authors.initials: R
authors.lastname: Poggiali
authors.forename: Cosetta
authors.initials: C
authors.lastname: Guarnieri
authors.forename: Barbara
authors.initials: B
authors.lastname: Biffi
authors.forename: Teresa
authors.initials: T
authors.lastname: La Ferlita
authors.forename: Valdo
authors.initials: V
authors.lastname: Ricca
authors.forename: Edoardo
authors.initials: E
authors.lastname: Mannucci
authors.forename: Carlo Maria
authors.initials: CM
authors.lastname: Rotella
mesh_terms: D000328:Adult; D001823:Body Composition; D015992:Body Mass Index; D004038:Diet, Reducing; D005260:Female; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009042:Motivation; D018482:Muscle, Skeletal; D009765:Obesity / Q000628:therapy*; D010342:Patient Acceptance of Health Care; D010352:Patient Dropouts; D010809:Physical Fitness; D016896:Treatment Outcome; D015431:Weight Loss; D061217:Weight Reduction Programs