title: Bioactive natural products derived from the Central African flora against neglected tropical diseases and HIV.
abstract: This review discusses the medicinal potential of bioactive metabolites isolated from medicinal plants in Central Africa for the treatment of neglected tropical diseases and HIV. A correlation is established between the biological activities of the isolated compounds and the uses of the plants in traditional medicine. Insight is provided on how secondary metabolites from medicinal plants in Central Africa could be exploited for drug discovery.
authors.affiliation: Biotechnology Unit, Department of Biochemistry and Molecular Biology, University of Buea, P. O. Box 63, Buea, Cameroon.
authors.forename: Denis
authors.initials: D
authors.lastname: Zofou
authors.forename: Fidele
authors.initials: F
authors.lastname: Ntie-Kang
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Sippl
authors.forename: Simon M N
authors.initials: SM
authors.lastname: Efange
mesh_terms: D000350:Africa, Central; D019380:Anti-HIV Agents / Q000494:pharmacology*; D016208:Databases, Factual; D055808:Drug Discovery; D019448:Ethnobotany; D008519:Medicine, Traditional; D010946:Plants, Medicinal / Q000737:chemistry*; D014330:Tropical Medicine
chemical_list: D019380:Anti-HIV Agents