title: Association between mammographic breast density and lifestyle in Japanese women.
abstract: A high mammographic breast density is considered to be a risk factor for breast cancer. However, only a small number of studies on the association between breast density and lifestyle have been performed. A cross-sectional study was performed using a survey with 29 questions on life history and lifestyle. The breast density on mammography was classified into 4 categories following the BI-RADS criteria. The subjects were 522 women with no medical history of breast cancer. The mean age was 53.3 years old. On multivariate analysis, only BMI was a significant factor determining breast density in premenopausal women (parameter estimate, -0.403; p value, 0.0005), and the density decreased as BMI rose. In postmenopausal women, BMI (parameter estimate, -0.196; p value, 0.0143) and number of deliveries (parameter estimate, -0.388; p value, 0.0186) were significant factors determining breast density;breast density decreased as BMI and number of deliveries increased. Only BMI and number of deliveries were identified as factors significantly influencing breast density. BMI was inversely correlated with breast density before and after menopause, whereas the influence of number of deliveries on breast density was significant only in postmenopausal women in their 50 and 60s.
authors.affiliation: Department of Radiology, Okayama Saiseikai General Hospital, Okayama 700-8511, Japan.
authors.forename: Setsuko
authors.initials: S
authors.lastname: Ishihara
authors.forename: Naruto
authors.initials: N
authors.lastname: Taira
authors.forename: Kensuke
authors.initials: K
authors.lastname: Kawasaki
authors.forename: Youichi
authors.initials: Y
authors.lastname: Ishibe
authors.forename: Taeko
authors.initials: T
authors.lastname: Mizoo
authors.forename: Keiko
authors.initials: K
authors.lastname: Nishiyama
authors.forename: Takayuki
authors.initials: T
authors.lastname: Iwamoto
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Nogami
authors.forename: Takayuki
authors.initials: T
authors.lastname: Motoki
authors.forename: Tadahiko
authors.initials: T
authors.lastname: Shien
authors.forename: Junji
authors.initials: J
authors.lastname: Matsuoka
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Doihara
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Komoike
authors.forename: Shuhei
authors.initials: S
authors.lastname: Sato
authors.forename: Susumu
authors.initials: S
authors.lastname: Kanazawa
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000208:ethnology; D044466:Asian People / Q000706:statistics & numerical data*; D015992:Body Mass Index; D000071060:Breast Density; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000208:ethnology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008019:Life Style; D042361:Mammary Glands, Human / Q000002:abnormalities; D008875:Middle Aged; D015999:Multivariate Analysis; D010298:Parity; D017698:Postmenopause; D017697:Premenopause; D011859:Radiography; D012307:Risk Factors; D012907:Smoking / Q000208:ethnology