title: [Multiresistant Organisms].
abstract: Infections caused by multidrug resistant (MDR) organisms are becoming more frequently in daily practice and are associated with an increase in duration of treatment and mortality. During the past decades, particular attention in the field of MDR pathogens was paid to methicillin-resistant staphylococcus aureus (MRSA). For the last years, MDR gram-negative organisms, with e.g., "extended-spectrum beta-lactamases" (ESBL), have been gaining a growing significance. Currently, treatment of infections with these organisms displays a greater challenge for the clinician compared to MRSA infections. This review illustrates the emergence of antibiotic resistance, provides information on the most important gram-negative and gram-positive bacteria, Clostridium difficile and measures to prevent their further spread.
authors.affiliation: Zentrum für Infektionsmedizin und Krankenhaushygiene, FSU Jena, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Hagel
authors.affiliation: KIM IV, Abteilung für Gastroenterologie, Hepatologie und Infektiologie, FSU Jena, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Stallmach
authors.affiliation: Institut für Medizinische Mikrobiologie, FSU Jena, Deutschland.
authors.forename: P
authors.initials: P
authors.lastname: Keller
authors.affiliation: Zentrum für Infektionsmedizin und Krankenhaushygiene, FSU Jena, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Pletz
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology* / Q000517:prevention & control; D003428:Cross Infection / Q000188:drug therapy* / Q000382:microbiology* / Q000517:prevention & control; D004203:Disinfection / Q000592:standards; D024901:Drug Resistance, Multiple, Bacterial; D004761:Enterocolitis, Pseudomembranous / Q000188:drug therapy / Q000382:microbiology / Q000517:prevention & control; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000382:microbiology / Q000517:prevention & control; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology / Q000517:prevention & control; D006235:Hand Disinfection / Q000592:standards; D006801:Humans; D010356:Patient Isolation; D011481:Protective Clothing
chemical_list: D000900:Anti-Bacterial Agents