title: Clinical significance of the first surveillance colonoscopy after endoscopic early colorectal cancer removal.
abstract: OBJECTIVE
  We investigated the clinical significance of the first surveillance colonoscopy after endoscopic cancer removal.
  
  
  METHODS
  We conducted a retrospective cohort study at a single center. Patients diagnosed with early colon cancer after endoscopic removal (index colonoscopy) and who underwent surveillance colonoscopy within 1 year were enrolled. All visible lesions were removed during index colonoscopy. Polyps newly detected at surveillance colonoscopy considered as lesions missed during index colonoscopy were analyzed. We investigated risk factors for missing an advanced lesion.
  
  
  RESULTS
  In total, 139 patients diagnosed with early colorectal cancer were enrolled. Overall 774 lesions were removed during index colonoscopy and an additional 222 lesions were newly detected at the surveillance colonoscopy. The lesion miss rate during index colonoscopy was 22.3%. The miss rates for advanced adenoma and cancer were 11.4% and 3.6%, respectively. Total number of polyps during index colonoscopy was an associated risk factor for missing an advanced lesion (odds ratio 1.176, 95% interval 1.062-1.303).
  
  
  CONCLUSIONS
  Synchronous advanced neoplasms can be missed during endoscopic removal in patients with early colorectal cancer. Clinical significance of the first surveillance colonoscopy after endoscopic early colorectal cancer removal is detection of missed synchronous advanced neoplasms during index colonoscopy.
authors.forename: Hyun Gun
authors.initials: HG
authors.lastname: Kim
authors.forename: Suck-Ho
authors.initials: SH
authors.lastname: Lee
authors.forename: Seong Ran
authors.initials: SR
authors.lastname: Jeon
authors.forename: Tae Hee
authors.initials: TH
authors.lastname: Lee
authors.forename: Bong Min
authors.initials: BM
authors.lastname: Ko
authors.forename: Jin-Oh
authors.initials: JO
authors.lastname: Kim
authors.forename: Joo Young
authors.initials: JY
authors.lastname: Cho
authors.forename: Joon Seong
authors.initials: JS
authors.lastname: Lee
mesh_terms: D000368:Aged; D003113:Colonoscopy / Q000379:methods*; D015179:Colorectal Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors