title: Predicting the need of tracheostomy amongst patients admitted to an intensive care unit: a multivariate model.
abstract: BACKGROUND
  Patients requiring prolonged invasive mechanical ventilation are prone to complications, such as infections, tracheal stenosis and death. It has been proposed that early tracheostomy could have a role in preventing these outcomes, but the proper identification of patients at risk can be difficult.
  
  
  OBJECTIVE
  The aim of this study was to develop a multivariate model that allows the early detection of patients that will require prolonged ventilatory support.
  
  
  METHODS
  A retrospective cohort study was undertaken in the intensive care unit of the Hospital Naval Almirante Nef, Chile, between June 2011 and June 2012. The charts of all intubated patients were reviewed in search for early predictors of prolonged intubation (>7 days). Multivariate logistic regression analysis was used to detect statistically significant associations and to assess potential confounders.
  
  
  RESULTS
  A total of 349 patients were admitted to the intensive care unit during the study period and 142 (40.7%) required invasive mechanical ventilation. Most of them were male (60.5%), with a mean age of 65.8 ± 16.7 years. Thirty-five patients (24%) required to be ventilated for 7 days or more, and 16 (46%) were tracheostomized for this reason. The regression model showed that older age (p=0.026), a Pa/Fi ratio of less than 200 (p=0.046), and the presence of chronic pulmonary disease (p=0.035) or hypernatremia (p=0.012) on intubation day were significantly associated with the requirement of prolonged intubation.
  
  
  CONCLUSIONS
  Invasive mechanical ventilation is a common reason for admittance to the ICU. The abovementioned predictors can be of assistance when selecting patients that could benefit from early tracheostomies, and are in agreement with earlier reports. Although the model's discriminating capacity was good, it is necessary to formally validate it before recommending its widespread use.
authors.affiliation: Escuela de Medicina, Universidad de Valparaíso, Valparaiso, Chile.
authors.forename: Cristian
authors.initials: C
authors.lastname: Papuzinski
authors.forename: Miguel
authors.initials: M
authors.lastname: Durante
authors.forename: Catalina
authors.initials: C
authors.lastname: Tobar
authors.forename: Felipe
authors.initials: F
authors.lastname: Martinez
authors.forename: Eduardo
authors.initials: E
authors.lastname: Labarca
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007297:Inpatients; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D008297:Male; D018579:Patient Selection; D011379:Prognosis; D012131:Respiratory Insufficiency / Q000628:therapy*; D012189:Retrospective Studies; D014139:Tracheostomy / Q000706:statistics & numerical data*