title: [Efficacy of dermoplasty and the dermal equivalent in treatment of vast leg ulcers of mixed genesis].
abstract: The most frequent causes of leg ulcers (90-95%) are chronic venous insufficiency (45-60%), obliterating atherosclerosis of the lower extremity arteries (10-20%), diabetes mellitus (15-25%) and their combinations (10-15%). The leg ulcers, specified as pyoderma gangrenosum, are the rare and severe pathology, which is very often misdiagnosed. The case history of a 58-year old female patient with vast leg ulcers of the both shanks is analyzed. The leg ulcers were caused by pyoderma gangrenosum and chronic venous insufficiency due to the varicose disease. Complete epithelization of both ulcers was achieved by means of dermoplasty combined using the dermal equivalent against the background of system immunosuppressive therapy.
authors.forename: D Iu
authors.initials: DIu
authors.lastname: Andreev
authors.forename: N V
authors.initials: NV
authors.lastname: Abramova
authors.forename: M I
authors.initials: MI
authors.lastname: Blinova
authors.forename: G P
authors.initials: GP
authors.lastname: Pinaev
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage; D001684:Biological Dressings; D017690:Cell Transplantation / Q000379:methods*; D003131:Combined Modality Therapy; D016572:Cyclosporine / Q000008:administration & dosage*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D007871:Leg Ulcer / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D008875:Middle Aged; D017762:Nadroparin / Q000008:administration & dosage; D017511:Pyoderma Gangrenosum / Q000150:complications*; D012086:Reoperation; D016038:Skin Transplantation / Q000379:methods*; D053828:Stockings, Compression; D016896:Treatment Outcome; D014648:Varicose Veins / Q000150:complications*
chemical_list: D000925:Anticoagulants; D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D017762:Nadroparin; D016572:Cyclosporine