title: Treatment of refractory perianal fistulas with ligation of the intersphincteric fistula tract: preliminary results.
abstract: Several surgical options exist for management of fistula in ano. The goal of treatment is to achieve closure of the fistula while maintaining continence. Sphincter-sparing operations to close perianal fistulas include advancement flap, anal fistula plug, fibrin glue, and fistulectomy. Variable success rates from 30 to 80 per cent have been reported. Ligation of intersphincteric fistula tract (LIFT), first described in 2007, has a reported success rate from 40 to 94 per cent. The objective of this study was to study our results of the LIFT procedure for refractory perianal fistulas. We conducted a retrospective 18-month review of consecutive patients with refractory perianal disease treated with the LIFT procedure at an academic, tertiary, colorectal practice. All patients undergoing a LIFT procedure for anal fistula from August 2010 to August 2012 were included in the study. The primary end points were success rates at 1 month and 3 months. Secondary end points were postoperative complications and maintenance of continence. Twenty patients underwent LIFT procedures of whom nine had previously failed treatments. Mean age was 45 years and included 12 male and eight female patients. Success rate at 1 month was 70 per cent (14 patients) and at 3 months was 80 per cent (16 patients). Success rates for patients with previously failed attempts were 67 per cent at 1 month and 89 per cent at 3 months. Continence was maintained in 100 per cent of patients. Our data support the use of the LIFT procedure for refractory perirectal fistulas.
authors.affiliation: Department of Surgery, Division of Colon and Rectal Surgery, University of South Florida, Tampa, Florida 33606, USA. mcampbe1@health.usf.edu
authors.forename: Michael L
authors.initials: ML
authors.lastname: Campbell
authors.forename: Elia Charbel
authors.initials: EC
authors.lastname: Abboud
authors.forename: Michael E
authors.initials: ME
authors.lastname: Dolberg
authors.forename: Jaime E
authors.initials: JE
authors.lastname: Sanchez
authors.forename: Jorge E
authors.initials: JE
authors.lastname: Marcet
authors.forename: Sowsan H
authors.initials: SH
authors.lastname: Rasheid
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005242:Fecal Incontinence / Q000517:prevention & control; D005260:Female; D006801:Humans; D008026:Ligation / Q000379:methods; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D012003:Rectal Fistula / Q000601:surgery*; D012086:Reoperation; D012189:Retrospective Studies; D016896:Treatment Outcome