title: Pharmacological treatments for obsessive-compulsive disorder in children and adolescents: a qualitative review.
abstract: We present the results of a systematic review on the effectiveness of pharmacological treatments for children and adolescents with obsessive-compulsive disorder. Sixty-four studies fulfilled the selection criteria, being the most of them focused in SSRI and Clomipramine. The trials on augmentation strategies and third line monotherapies are scarce, being the majority open-trials and case series. Similarly, studies on combined treatment (psychological and pharmacological) are few; furthermore this is a relevant future research line. It is also remarkable the lack of quasi-experimental and experimental comparison studies and the long-term follow-up measures.
authors.affiliation: Departamento de Personalidad, Evaluación y Tratamiento Psicológico, Facultad de Psicología, Universidad de Murcia, Murcia, Spain. airosa@um.es
authors.forename: Ana I
authors.initials: AI
authors.lastname: Rosa-Alcázar
authors.forename: Marina
authors.initials: M
authors.lastname: Iniesta-Sepúlveda
authors.forename: Angel
authors.initials: A
authors.lastname: Rosa-Alcázar
mesh_terms: D000293:Adolescent; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D002648:Child; D015928:Cognitive Behavioral Therapy; D003131:Combined Modality Therapy; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy* / Q000628:therapy; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use
chemical_list: D000929:Antidepressive Agents, Tricyclic; D017367:Selective Serotonin Reuptake Inhibitors