title: Cationic dirhodium carboxylate-catalyzed synthesis of dihydropyrimidones from propargyl ureas.
abstract: Cationic Rh(II) complexes are able to catalyze the regioselective hydroamination of propargyl ureas in a 6-endo fashion. This transformation permits access to interesting substitution patterns of dihydropyrimidines which have found use as nucleotide exchange factor inhibitors.
authors.affiliation: Department of Chemistry, University of Utah, Salt Lake City, UT 84112, United States.
authors.forename: Miao
authors.initials: M
authors.lastname: Yang
authors.forename: Shannon J
authors.initials: SJ
authors.lastname: Odelberg
authors.forename: Zongzhong
authors.initials: Z
authors.lastname: Tong
authors.forename: Dean Y
authors.initials: DY
authors.lastname: Li
authors.forename: Ryan E
authors.initials: RE
authors.lastname: Looper
keywords: ARF 6; Rhodium catalysis; dihydropyrimidone; heterocycle; hydroamination