title: Standard versus extended pancreaticoduodenectomy in treating adenocarcinoma of the head of the pancreas.
abstract: OBJECTIVE
  To compare the postoperative complications and survival of standard pancreatoduodenectomy (SPD) and extended pancreatoduodenectomy (EPD) in patients with resectable adenocarcinoma of the head of the pancreas.
  
  
  METHODS
  Between January 1994 and December 2011, 165 patients with biopsy-proven adenocarcinoma of the pancreatic head were treated in West China Hospital, among whom 93 underwent SPD and 72 had EPD. Complications and survival after the surgery were analyzed retrospectively.
  
  
  RESULTS
  The median operation time of the EPD group was longer compared with the SPD group (375 minutes vs.310 minutes, P<0.01), the volume of blood transfusion was larger (700 mL vs.400 mL, P<0.05), while the median hospital stay (13.5 days vs.12 days, P=0.79) and the total complication rates were comparable (34.7% vs.32.4%, P=0.93). The total recurrence rates of the SPD and EPD groups were not significantly different (52.7% vs. 43.1%, P=0.83). No significant differences were found between the SPD and EPD groups in 1-year (81.7% vs. 86.1%), 3-year (38.7% vs. 43.1%), 5-year (16.7% vs. 19.4%), and median survivals (19.8 months vs. 23.2 months, P= 0.52).
  
  
  CONCLUSIONS
  The postoperative complications and survival donot differ significantly between SPD and EPD.
authors.affiliation: Department of Hepatobiliary and Pancreatic Surgery, Sichuan Academy of Medical Science and Sichuan Provincial People's Hospital, Chengdu 610072, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Gong
authors.forename: Gang
authors.initials: G
authors.lastname: Mai
authors.forename: Zhen-jiang
authors.initials: ZJ
authors.lastname: Zheng
authors.forename: Guang-ming
authors.initials: GM
authors.lastname: Xiang
authors.forename: Wei-ming
authors.initials: WM
authors.lastname: Hu
authors.forename: Bo-le
authors.initials: BL
authors.lastname: Tian
authors.forename: Zhao-da
authors.initials: ZD
authors.lastname: Zhang
authors.forename: Xu-bao
authors.initials: XB
authors.lastname: Liu
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000601:surgery*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000601:surgery*; D016577:Pancreaticoduodenectomy / Q000009:adverse effects / Q000379:methods*; D012189:Retrospective Studies