title: Study on the treatment of acute thallium poisoning.
abstract: BACKGROUND
  Acute thallium poisoning rarely occurs but is a serious and even fatal medical condition. Currently, patients with acute thallium poisoning are usually treated with Prussian blue and blood purification therapy. However, there are few studies about these treatments for acute thallium poisoning.
  
  
  METHODS
  Nine patients with acute thallium poisoning from 1 family were treated successfully with Prussian blue and different types of blood purification therapies and analyzed.
  
  
  RESULTS
  Prussian blue combined with sequential hemodialysis, hemoperfusion and/or continuous veno-venous hemofiltration were effective for the treatment of patients with acute thallium poisoning, even after delayed diagnosis.
  
  
  CONCLUSIONS
  Blood purification therapies help in the clearance of thallium in those with acute thallium poisoning. Prussian blue treatment may do the benefit during this process.
authors.affiliation: Blood Purification Center (H-TZ, X-GZ) and Department of Urology (B-PQ), The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Institute of Nephrology (H-TZ), Zhengzhou University, Zhengzhou, China; Key Discipline Laboratory of Clinical Medicine (H-TZ, B-PQ), Jiaozuo, China; and Department of Nuclear Medicine (B-PL), The Second Charity Hospital of Henan Province, Jiaozuo, China.
authors.forename: Hong-Tao
authors.initials: HT
authors.lastname: Zhang
authors.forename: Bao-Ping
authors.initials: BP
authors.lastname: Qiao
authors.forename: Bao-Ping
authors.initials: BP
authors.lastname: Liu
authors.forename: Xian-Guo
authors.initials: XG
authors.lastname: Zhao
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000505:Alopecia / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy*; D000931:Antidotes / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005295:Ferrocyanides / Q000627:therapeutic use*; D000075322:Heavy Metal Poisoning; D006464:Hemoperfusion / Q000379:methods / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011041:Poisoning / Q000175:diagnosis / Q000628:therapy*; D013793:Thallium / Q000506:poisoning*; D016896:Treatment Outcome
chemical_list: D000931:Antidotes; D005295:Ferrocyanides; D013793:Thallium; C000170:ferric ferrocyanide