title: Metastatic squamous cell carcinoma of an unknown primary site with cardiac involvement: case report.
abstract: Head and neck squamous cell carcinomas frequently metastasize to cervical lymph nodes. Distant metastasis by hematogenous dissemination pathways is less common. Cardiac involvement is a particularly rare occurrence. The first case of cardiac metastasis was reported in the early 18th century as a postmortem discovery. Since then, there have been sporadic reports of oropharyngeal cancer with cardiac metastasis. This report describes a case of metastatic squamous cell carcinoma of an unknown primary site involving the lungs, heart, and soft tissue of the bilateral paraspinal regions and lower extremity.
authors.affiliation: Chief Resident, Division of Oral and Maxillofacial Surgery, University of Florida, College of Medicine, Jacksonville, FL.
authors.forename: Reza
authors.initials: R
authors.lastname: Fouladi
authors.forename: Phillip
authors.initials: P
authors.lastname: Pirgousis
authors.forename: Rui P
authors.initials: RP
authors.lastname: Fernandes
mesh_terms: D034861:Abdominal Wall / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000556:secondary*; D005260:Female; D006338:Heart Neoplasms / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis / Q000473:pathology; D008875:Middle Aged; D009334:Neck Muscles / Q000473:pathology; D009382:Neoplasms, Unknown Primary / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000556:secondary; D013848:Thigh / Q000473:pathology