title: Assessment of bronchodilator response in preschool children by pulmonary function tests.
abstract: We performed pulmonary function test to document bronchodilator response by using tidal breathing flow volume loop (TBFVL), rapid thoracic compression (RTC), and raised volume rapid thoracic compression (RVRTC) techniques. Thirty-nine children (mean age 45.2 months) were evaluated. The parameters that showed significant improvement after bronchodilator administration included TEF10/ PTEF ratio in TBFVL, and FEF25-75%, FEV1 and PEF in RVRTC. None of the parameters measured in RTC showed significant improvement. We conclude FEV1, PEF and FEF 25-75% in RVRTC have greater sensitivity for detection of airways changes.
authors.affiliation: Division of Pulmonology, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India. Correspondence to: Dr S K Kabra, Professor, Division of Pulmonology, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India. skkabra@hotmail.com.
authors.forename: Babak
authors.initials: B
authors.lastname: Ghalibafsabbaghi
authors.forename: Dinesh
authors.initials: D
authors.lastname: Raj
authors.forename: Rakesh
authors.initials: R
authors.lastname: Lodha
authors.forename: S K
authors.initials: SK
authors.lastname: Kabra
mesh_terms: D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology; D001993:Bronchodilator Agents / Q000008:administration & dosage*; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012129:Respiratory Function Tests; D012143:Respiratory Physiological Phenomena / Q000187:drug effects*
chemical_list: D001993:Bronchodilator Agents