title: Risk factors for injury acute renal in patients with severe trauma and its effect on mortality.
abstract: The studies which associated acute kidney injury (AKI) and trauma emerged during the Second World War, and since then we have seen a progressive evolution of healthcare aiming at AKI prevention. However, establishing the risk factors for post-trauma AKI development remains crucial and may help reduce this complication.
  
  
  OBJECTIVE
  This study aims at identifying risk factors vis-à-vis the development of AKI in patients with severe trauma and its impact on mortality. This is a retrospective study of 75 patients with severe trauma. Six were taken off because they arrived at the hospital past the point of resuscitation.
  
  
  METHODS
  The variables considered were age, gender, trauma severity according to the Injury Severity Score (ISS) and the Glasgow Coma Scale (GCS), trauma mechanism, mean blood pressure upon admission, fluid replacement in the first 24 hours, serum creatinine levels, use of nephrotoxic antibiotics, length of hospital stay, need for ICU admission and mortality.
  
  
  RESULTS
  The prevalence of AKI in severe trauma patients was 17.3%, and the factors associated with ARF in this sample were Head Injury and GCS < 10. Mortality, length of hospital stay and the need for ICU were significantly higher in patients who developed AKI.
  
  
  CONCLUSIONS
  The identification of these risk factors is of paramount importance for the development of care strategies for patients suffering from severe trauma, for the prevention of acute kidney injury and the associated high mortality.
authors.affiliation: Medical Residency Program in Trauma Surgery - FUNFARME/FAMERP Base Hospital. albaitello@gmail.com
authors.forename: André Luciano
authors.initials: AL
authors.lastname: Baitello
authors.forename: Gustavo
authors.initials: G
authors.lastname: Marcatto
authors.forename: Roberto Kaoru
authors.initials: RK
authors.lastname: Yagi
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000401:mortality*; D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D014947:Wounds and Injuries / Q000150:complications* / Q000401:mortality*; D055815:Young Adult