title: Boosting lymphocyte production.
abstract: How lymphoid cell fate is orchestrated in early hematopoietic progenitors remains poorly understood. In this issue of Immunity, Satoh et al. (2013) show that the chromatin remodeler Satb1 promotes lymphocyte differentiation in both young and aged stem cells.
authors.affiliation: Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093-0377, USA. murre@biomail.ucsd.edu
authors.forename: Cornelis
authors.initials: C
authors.lastname: Murre
mesh_terms: D000818:Animals; D006412:Hematopoietic Stem Cells / Q000502:physiology*; D006801:Humans; D038041:Lymphopoiesis; D036961:Matrix Attachment Region Binding Proteins / Q000378:metabolism*; D013601:T-Lymphocytes / Q000502:physiology*
chemical_list: D036961:Matrix Attachment Region Binding Proteins; C469541:Satb1 protein, mouse