title: Preparation and characterization of alkyl methacrylate-based monolithic columns for capillary gas chromatography applications.
abstract: Gas chromatography (GC) is considered the least common application of both polymer and silica-based monolithic columns. This study describes the fabrication of alkyl methacrylate monolithic materials for use as stationary phases in capillary gas chromatography. Following the deactivation of the capillary surface with 3-(trimethoxysilyl)propyl methacrylate (TMSM), the monoliths were formed by the co-polymerization of either hexyl methacrylate (HMA) or lauryl methacrylate (LMA) with different percentage of ethylene glycol dimethacrylate (EDMA) in presence of an initiator (azobisisobutyronitrile, AIBN) and a mixture of porogens include 1-propanol, 1,4-butanediol and water. The monoliths were prepared in 500mm length capillaries possessing inner diameters of 250μm. The efficiencies of the monolithic columns for low molecular weight compounds significantly improved as the percentage of crosslinker was increased, because of the greater proportion of pores less than 50nm. The columns containing lower percentages of crosslinker were able to rapidly separate a series of 8 alkane members in 0.7min, but the separation was less efficient for the light alkanes. Columns prepared with the lauryl methacrylate monomer yielded a different morphology for the monolith-interconnected channels. The channels were more branched, which increased the separation time, and unlike the other columns, allowed for temperature programming.
authors.affiliation: Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. ch_kareemyusuf@yahoo.com
authors.forename: Kareem
authors.initials: K
authors.lastname: Yusuf
authors.forename: Ahmad
authors.initials: A
authors.lastname: Aqel
authors.forename: Zeid
authors.initials: Z
authors.lastname: A L Othman
authors.forename: Ahmed Yacine
authors.initials: AY
authors.lastname: Badjah-Hadj-Ahmed
mesh_terms: D000473:Alkanes / Q000032:analysis / Q000302:isolation & purification; D002849:Chromatography, Gas / Q000295:instrumentation* / Q000379:methods; D005742:Gasoline / Q000032:analysis; D057446:Hydrodynamics; D008689:Methacrylates / Q000737:chemistry*; D008956:Models, Chemical; D016062:Porosity
chemical_list: D000473:Alkanes; D005742:Gasoline; D008689:Methacrylates
keywords: Alkanes separation; Gas chromatography; Methacrylate polymer; Monolith