title: Identification of human tissue cross-presenting dendritic cells: A new target for cancer vaccines.
abstract: Dendritic cells (DCs) are a heterogeneous group of functionally specialized antigen-presenting cells. We recently characterized the human tissue cross-presenting DCs and aligned the human and mouse DC subsets. Our findings will facilitate the translation of murine DC studies to the human setting and aid the design of DC-based vaccine strategies for infection and cancer immunotherapy.
authors.affiliation: Institute of Cellular Medicine; Newcastle University; Newcastle upon Tyne, UK.
authors.forename: Muzlifah
authors.initials: M
authors.lastname: Haniffa
authors.forename: Matthew
authors.initials: M
authors.lastname: Collin
authors.forename: Florent
authors.initials: F
authors.lastname: Ginhoux
keywords: XCR1; cross-presentation; dendritic cell; subset; transcriptomic analysis