title: Personal history of major depression may put women at risk for premenstrual dysphoric symptomatology.
abstract: BACKGROUND
  Premenstrual dysphoric disorder (PMDD) is a chronic condition that significantly affects a woman's well-being on a monthly basis. Although co-occurrence of PMDD and major depressive disorder (MDD) is common, most studies examine whether women with PMDD are at risk for depression and investigations of PMDD in depressed women are scant. Therefore, the present study examined rates of PMDD in young depressed women.
  
  
  METHODS
  PMDD was assessed using a structured clinical interview (SCID-PMDD) in a sample of 164 young women with (n=85) and without (n=79) any history of depression.
  
  
  RESULTS
  Rates of PMDD were elevated among women with MDD in this sample. This result held true regardless of participants' MDD status (current, lifetime or past history-only symptoms of MDD) and regardless of whether all or most DSM-IV-TR PMDD criteria were met.
  
  
  CONCLUSIONS
  Sample size in the present study was relatively small, and daily diary data were not available to confirm a PMDD diagnosis.
  
  
  CONCLUSIONS
  The current study highlights the need for clinicians to assess for PMDD in young female patients with major depression. Depressed women experiencing the added physical and psychological burden of PMDD may have a more severe disease course, and future studies will need to identify appropriate treatments for this subset of depressed women.
authors.affiliation: Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Box 951563, Los Angeles, CA 90095-1563, USA. eaccortt@psych.ucla.edu
authors.forename: Eynav E
authors.initials: EE
authors.lastname: Accortt
authors.forename: Anya V
authors.initials: AV
authors.lastname: Kogan
authors.forename: John J B
authors.initials: JJ
authors.lastname: Allen
mesh_terms: D000293:Adolescent; D015897:Comorbidity; D003865:Major Depressive Disorder / Q000453:epidemiology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D011293:Premenstrual Syndrome / Q000175:diagnosis* / Q000453:epidemiology*; D055815:Young Adult
keywords: Comorbidity; Major depressive disorder; Premenstrual dysphoric disorder