title: Pleiotropic effects of GacA on Pseudomonas fluorescens Pf0-1 in vitro and in soil.
abstract: Pseudomonas species can exhibit phenotypic variation resulting from gacS or gacA mutation. P. fluorescens Pf0-1 is a gacA mutant and exhibits pleiotropic changes following the introduction of a functional allele. GacA enhances biofilm development while reducing dissemination in soil, suggesting that alternative Gac phenotypes enable Pseudomonas sp. to exploit varied environments.
authors.affiliation: Center for Adaptation Genetics and Drug Resistance, Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
authors.forename: Sarah C
authors.initials: SC
authors.lastname: Seaton
authors.forename: Mark W
authors.initials: MW
authors.lastname: Silby
authors.forename: Stuart B
authors.initials: SB
authors.lastname: Levy
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D018441:Biofilms / Q000254:growth & development; D017353:Gene Deletion; D005816:Genetic Complementation Test; D011551:Pseudomonas fluorescens / Q000235:genetics* / Q000502:physiology; D012988:Soil Microbiology
chemical_list: D001426:Bacterial Proteins; C091100:GacA protein, Bacteria