title: [Capsid protein L1 HPV-16 in a modified cervical epithelium].
abstract: The 58 cervical biopsies were studied by cytological, histological, immunomorphological methods, electron microscopy and PCR. Expression of L1 was observed only in the differentiated cells of squamous and metaplastic cervical epithelium. At increase of grade of cervical epithelial lesion decrease expression L1 from 75% of cases of CIN1 up to 28.5% of cases of SCC. Not all capsid structures connect with DNA HPV in case of CIN3.
authors.forename: V A
authors.initials: VA
authors.lastname: Ershov
authors.forename: E V
authors.initials: EV
authors.lastname: Il'inskaia
mesh_terms: D000328:Adult; D000368:Aged; D036022:Capsid Proteins; D002294:Carcinoma, Squamous Cell / Q000737:chemistry* / Q000556:secondary; D002584:Cervix Uteri / Q000737:chemistry / Q000473:pathology / Q000821:virology; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D052162:Human papillomavirus 16 / Q000737:chemistry*; D006801:Humans; D007150:Immunohistochemistry; D008854:Microscopy, Electron; D008875:Middle Aged; D060787:Neoplasm Grading; D015514:Oncogene Proteins, Fusion / Q000032:analysis*; D009856:Oncogene Proteins, Viral / Q000032:analysis*; D016133:Polymerase Chain Reaction; D002583:Uterine Cervical Neoplasms / Q000737:chemistry* / Q000473:pathology* / Q000821:virology; D002578:Uterine Cervical Dysplasia / Q000737:chemistry* / Q000473:pathology* / Q000821:virology
chemical_list: D036022:Capsid Proteins; D004279:DNA, Viral; D015514:Oncogene Proteins, Fusion; D009856:Oncogene Proteins, Viral