title: Antibacterial and antioxidant activity of lichen species Ramalina roesleri.
abstract: Solvent extracts of Ramalina roesleri Nyl were assayed for antimicrobial and antioxidant activity. Hexane extract was highly active against Staphylococcus aureus and Streptococcus mutans. The 1,1-diphenyl-2-picryl-hydrazil (DPPH) radical scavenging activity of extracts ranged from 29.42% to 87.90%. Atranorin, protolichesterinic acid, usnic acid, 2-hydroxy-4-methoxy-6-propyl benzoic acid, homosekikaic acid, sekikaic acid, benzoic acid, 2,4-dihydroxy-6-propyl and 2,4-dihydroxy-3,6-dimethyl benzoate were isolated from the hexane extract. Maximum DPPH radical scavenging activity was exhibited by sekikaic acid followed by homosekikaic acid.
authors.affiliation: a Division of Agricultural Chemicals, Indian Agricultural Research Institute , New Delhi , 110012 , India.
authors.forename: R
authors.initials: R
authors.lastname: Sisodia
authors.forename: M
authors.initials: M
authors.lastname: Geol
authors.forename: S
authors.initials: S
authors.lastname: Verma
authors.forename: A
authors.initials: A
authors.lastname: Rani
authors.forename: P
authors.initials: P
authors.lastname: Dureja
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002853:Chromatography, Liquid; D004353:Drug Evaluation, Preclinical; D020128:Inhibitory Concentration 50; D008011:Lichens / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D010936:Plant Extracts