title: HEPA and PARSE: Systematic discovery of clinically relevant tumor-specific antigens.
abstract: The effective discovery of tumor-specific antigens (TSAs) holds the key for the development of new diagnostic assays and immunotherapeutic approaches against cancer. Here, we discuss our recently developed technologies, HEPA and PARSE, which allow for the systematic identification of TSAs, generating a reservoir of immunologically and clinically relevant targets.
authors.affiliation: Department of Immunology; Peking University Health Science Center; Beijing, China.
authors.forename: Qing-Wen
authors.initials: QW
authors.lastname: Xu
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xiao-Song
authors.initials: XS
authors.lastname: Wang
keywords: autoantibody signatures; gene expression profiling; immunodiagnosis; tumor-specific antigen