title: Topical medications as treatment of neuropathic orofacial pain.
abstract: Understanding mechanisms of neuropathic orofacial pain, targets of treatment, and basic pharmacology and working with informed compounding pharmacists may result in significant benefit for patients. The clinical significance of topical medications is improvement of quality of life for patients by providing a unique medication delivery system for neuropathic orofacial pain and other dental and extraoral conditions. The use of this route of administration has decreased or minimized side effects compared with other methods and is especially useful in medically compromised and elderly patients. These innovations, supported and improved by ongoing research, will augment the armamentarium of the clinician treating orofacial pain disorders.
authors.affiliation: Department of Diagnostic Sciences, Center for Temporomandibular Disorders and Orofacial Pain, University of Medicine and Dentistry of New Jersey, 110 Bergen Street - Room D 860, Newark, NJ 07103, USA.
authors.forename: Cibele
authors.initials: C
authors.lastname: Nasri-Heir
authors.forename: Junad
authors.initials: J
authors.lastname: Khan
authors.forename: Gary M
authors.initials: GM
authors.lastname: Heir
mesh_terms: D000279:Administration, Cutaneous; D002211:Capsaicin / Q000008:administration & dosage; D016861:Cyclooxygenase Inhibitors / Q000008:administration & dosage; D004008:Diclofenac / Q000008:administration & dosage; D005157:Facial Pain / Q000188:drug therapy*; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage; D009437:Neuralgia / Q000188:drug therapy*; D018689:Sensory System Agents / Q000008:administration & dosage; D061567:Voltage-Gated Sodium Channel Blockers / Q000008:administration & dosage
chemical_list: D016861:Cyclooxygenase Inhibitors; D018689:Sensory System Agents; D061567:Voltage-Gated Sodium Channel Blockers; D004008:Diclofenac; D008012:Lidocaine; D002211:Capsaicin