title: Neonatal brain protection in cardiac surgery and the role of intraoperative neuromonitoring.
abstract: Improving mortality rates in children undergoing surgery for congenital heart disease has enabled a shift in focus to improving morbidity, particularly with respect to neurological complications. Various factors have been implicated in influencing neurological outcomes. We share our experience in formulating a customized cardiopulmonary bypass (CPB) protocol based on currently available evidence. Theoretical advantages of intraoperative neuromonitoring during CPB, specifically use of near-infrared spectroscopy, will be discussed in the context of methodologies to monitor cerebral perfusion during surgery.
authors.affiliation: Division of Congenital Heart Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
authors.forename: Muhammad S
authors.initials: MS
authors.lastname: Khan
authors.forename: Charles D
authors.initials: CD
authors.lastname: Fraser
keywords: antegrade cerebral perfusion; cardiopulmonary bypass; deep hypothermic circulatory arrest; near-infrared spectroscopy