title: [Determination of chromium in capsule by inductively coupled plasma-mass spectrometry].
abstract: OBJECTIVE
  To establish the method which determined the content of chromium(Cr) in capsule by inductively coupled plasma-mass spectrometry.
  
  
  METHODS
  Pre-digestion-microwave digestion procedures were applied to extract Cr from the capsules. The potentially interfering 40Ar12C+ and 37Cl16O+ at the chromium masses m/z 52 and 53 were reduced in intensity by approximately 2 orders of magnitude by using 0. 6 ml/min NH3 as reactive cell gas in the dynamic reaction cell (DRC) while a Rpq value of 0.55 was used.
  
  
  RESULTS
  The correlation coefficient (r) of standard curve was 0.9996, and the detection limit of the method was 0.03 mg/kg, and the average recoveries for all determinations ranged from 86.5% to 107.8% with the related standard deviation below 5%.
  
  
  CONCLUSIONS
  The method, which is of good precision and accuracy, is applicable to rapid and accurate determination of chromium content in capsule.
authors.affiliation: Institute of Environmental Health & Related Products Safety, China CDC, Beijing 100021, China. cdcchenxi@hotmail.com
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
authors.forename: Miao
authors.initials: M
authors.lastname: Zhang
authors.forename: Hui
authors.initials: H
authors.lastname: Fu
authors.forename: Cixian
authors.initials: C
authors.lastname: Xu
authors.forename: Shaobin
authors.initials: S
authors.lastname: Lin
mesh_terms: D002214:Capsules / Q000009:adverse effects* / Q000737:chemistry*; D002857:Chromium / Q000032:analysis*; D013058:Mass Spectrometry / Q000379:methods; D008872:Microwaves; D012680:Sensitivity and Specificity; D013054:Spectrophotometry, Atomic / Q000379:methods*
chemical_list: D002214:Capsules; D002857:Chromium