title: Note on the measurement of bulk density and tapped density of powders according to the European Pharmacopeia.
abstract: The apparent volume and compressibility index of commonly used excipients were evaluated according to European Pharmacopeia monograph (seventh edition) in order to study the influence of the procedure conditions. The results suggested that the leveling of the powder inside the cylinder ought to be avoided.
authors.affiliation: Research Centre for Pharmaceutical Sciences, Department of Drug Sciences, Faculdade de Farmácia, Universidade do Porto, R. Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal. paulo.silva@ff.up.pt
authors.forename: J P
authors.initials: JP
authors.lastname: Sousa e Silva
authors.forename: D
authors.initials: D
authors.lastname: Splendor
authors.forename: I M B
authors.initials: IM
authors.lastname: Gonçalves
authors.forename: P
authors.initials: P
authors.lastname: Costa
authors.forename: J M
authors.initials: JM
authors.lastname: Sousa Lobo
mesh_terms: D002626:Chemistry, Pharmaceutical; D005062:European Union; D010602:Pharmacopoeias as Topic; D011208:Powders
chemical_list: D011208:Powders