title: Aggressive parenteral nutrition in sick very low birth weight babies: a randomized controlled trial.
abstract: Survival of preterm neonates in developing world has improved. Developing countries lag behind in nutritional management in NICU especially parenteral nutrition (PN). This randomized controlled trial was done to evaluate the effect of aggressive parenteral nutrition on nitrogen retention of sick VLBW and extremely low birth weight (ELBW) babies. From September 2009 to February 2010, total 34 babies were randomized to receive aggressive parenteral nutrition (APN)(n=17) or standard parenteral nutrition (SPN) (n=17). The average daily total and PN calory intake of babies in APN group was significantly higher during first week. APN was well-tolerated; however, nitrogen retention was not significantly higher in APN group. Aggressive parenteral nutrition in sick VLBW babies is feasible in developing world, though it did not improve nitrogen retention in first week of life.
authors.affiliation: Division of Neonatology, Department of Pediatrics, KEM Hospital, Rasta Peth, Pune 411011 and *Department of Health Sciences, University of Pune, Pune 411007, India. Correspondence to: Dr Amit Tagare, Neonatologist, Department of Pediatrics, Bharati Vidyapeeth Deemed University Medical College and Hospital, Sangli Miraj Road, Sangli 416 414, Pune, Maharasthra, India. docamikast@gmail.com.
authors.forename: Amit
authors.initials: A
authors.lastname: Tagare
authors.forename: Meenal
authors.initials: M
authors.lastname: Walawalkar
authors.forename: Umesh
authors.initials: U
authors.lastname: Vaidya
mesh_terms: D015331:Cohort Studies; D004435:Eating; D006801:Humans; D052577:Infant, Extremely Low Birth Weight / Q000378:metabolism; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight / Q000378:metabolism*; D010288:Parenteral Nutrition / Q000379:methods* / Q000706:statistics & numerical data; D016896:Treatment Outcome