title: [Prenatal cerebrovascular accidents diagnosed in the early infant stage: a series of 10 patients].
abstract: INTRODUCTION. A foetal or prenatal cerebrovascular accident (CVA) is defined as an ischaemic, thrombotic or arterial or venous haemorrhagic event that occurs between the 14th week of gestation and the onset of labour. PATIENTS AND METHODS. We report a retrospective study of a series of 10 patients suffering from a, presumably foetal, stroke that went unnoticed during the pregnancy and was diagnosed in the early infant stage. The symptoms and the age at which they were identified are highlighted. RESULTS. None of the 10 patients studied presented any relevant events in the mothers' medical history, but there were four threats of a preterm birth that were solved using the usual means and without the occurrence of any alterations that later affected the foetus. The studies that led to the diagnosis were carried out between the sixth and ninth months of life, and the reason for visiting was reported by the family as being a lower degree of mobility on one side of the body with respect to the other. Two patients presented thrombophilia. With a mean follow-up time of six years, all the patients have an associated infantile cerebral palsy, a third of them have epilepsy and 75% have learning difficulties or intellectual disability. CONCLUSIONS. When CVA are not detected in the prenatal period, it is important in primary care to look for and detect the warning signs of the psychomotor development of the infant at an early stage in order to begin a study of the case and to undertake rehabilitation as early as possible.
authors.affiliation: Unidad de Neuropediatría, Hospital General Universitario de Alicante, Alicante, Spain.
authors.forename: María
authors.initials: M
authors.lastname: Pina-Jover
authors.forename: María
authors.initials: M
authors.lastname: Martinez-Del Villar
authors.forename: Lucía
authors.initials: L
authors.lastname: Lillo-Laguna
authors.forename: Rocío
authors.initials: R
authors.lastname: Jadraque-Rodriguez
authors.forename: Pedro
authors.initials: P
authors.lastname: Martinez-Pastor
authors.forename: Jenaro
authors.initials: J
authors.lastname: Jover-Cerda
authors.forename: Francisco
authors.initials: F
authors.lastname: Gomez-Gosalvez
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D001925:Brain Damage, Chronic / Q000151:congenital / Q000209:etiology*; D002547:Cerebral Palsy / Q000209:etiology; D004827:Epilepsy / Q000151:congenital / Q000209:etiology; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007859:Learning Disabilities / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008423:Maternal Age; D010291:Paresis / Q000151:congenital / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications; D012189:Retrospective Studies; D020521:Stroke / Q000150:complications / Q000196:embryology*; D063189:Symptom Assessment; D019851:Thrombophilia / Q000150:complications / Q000196:embryology; D055815:Young Adult