title: [Systemic vasculitides: diagnostic stages].
abstract: OBJECTIVE
  To present systemic vasculitis (SV) diagnostic stages.
  
  
  METHODS
  Immunological and hemostatic parameters were determined, vascular scanning, histological and immunomorphological studies were performed in 360 patients.
  
  
  RESULTS
  The main diagnostic searching stages were presented, which could reveal the key clinical signs of vasculitis and systemacy of the process, differentiate primary and secondary vasculitides, conduct clinical and instrumental studies, detect specific markers of vascular wall injury, perform a morphological study of biopsy specimens, identify the major pathogenic components of vascular bed lesion, define the possible etiology and form of vasculitis, and make a nosological diagnosis.
  
  
  CONCLUSIONS
  The proposed diagnostic steps will be able to specify the nosological form of SV and the activity of the process and to define approaches to pathogenetic therapy.
authors.forename: N P
authors.initials: NP
authors.lastname: Shilkina
authors.forename: I V
authors.initials: IV
authors.lastname: Driazhenkova
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D006801:Humans; D012720:Severity of Illness Index; D056647:Systemic Vasculitis / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D013997:Time Factors
chemical_list: D015415:Biomarkers