title: [Osteoplastic effectiveness of mineralized bone matrix].
abstract: In the experiment conducted on 50 Wistar rats, the peculiarities of the reparative osteogenesis were studied using scanning electron microscopy, x-ray electron-probe microanalysis and histological techniques. Granulated mineralized bone matrix (MBM) obtained without thermal and demineralizing treatment, was implanted into the tibial defect. MBM was found to possess marked osteoinductive and osteoconductive properties. It induced a prolonged activation of reparative osteogenesis after the implantation, as well as deep bone tissue ingrowth into the implant, acceleration of organotypic remodeling of regenerated bone, intense angiogenesis and early restoration of the damaged
mesh_terms: D000818:Animals; D001861:Bone Regeneration; D018786:Bone Substitutes; D002113:Calcification, Physiologic; D005260:Female; D008297:Male; D010012:Osteogenesis; D051381:Rats; D017208:Rats, Wistar; D013977:Tibia / Q000293:injuries* / Q000473:pathology
chemical_list: D018786:Bone Substitutes