title: Report of the second joint meeting of ESOT and AST: current pipelines in biotech and pharma.
abstract: Following the first joint meeting organized by the European (ESOT) and American (AST) Societies of Transplantation in 2010, a second joint meeting was held in Nice, France, on October 12-14, 2012 at the Palais de la Mediterannee. Co-chairs of the scientific advisory committee were Dr. Flavio Vincenti (AST) and Dr. Teun Van Gelder (ESOT). The goal was to discuss the key unmet needs in solid organ transplantation with the opportunity to interrelate current basic research efforts with clinical translation. Thus, the topic of this second meeting "Transformational therapies and diagnostics in transplantation" was devised and a summary of this meeting follows.
authors.affiliation: Erasmus MC, Rotterdam, The Netherlands. t.vangelder@erasmusmc.nl
authors.forename: Teun
authors.initials: T
authors.lastname: van Gelder
authors.forename: Carla
authors.initials: C
authors.lastname: Baan
authors.forename: Flavio
authors.initials: F
authors.lastname: Vincenti
authors.forename: Roslyn B
authors.initials: RB
authors.lastname: Mannon
mesh_terms: D000069594:Abatacept; D001402:B-Lymphocytes / Q000276:immunology; D065095:Calcineurin Inhibitors; D064987:Cell- and Tissue-Based Therapy; D051799:Delayed Graft Function / Q000276:immunology / Q000628:therapy; D006084:Graft Rejection / Q000276:immunology / Q000517:prevention & control; D006650:Histocompatibility Testing; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D018796:Immunoconjugates / Q000627:therapeutic use; D007165:Immunosuppression Therapy / Q000379:methods; D053616:Janus Kinase 3 / Q000037:antagonists & inhibitors; D016030:Kidney Transplantation / Q000379:methods; D016377:Organ Transplantation; D010880:Piperidines / Q000627:therapeutic use; D011493:Protein Kinase C / Q000037:antagonists & inhibitors; D011743:Pyrimidines / Q000627:therapeutic use; D011758:Pyrroles / Q000627:therapeutic use; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D065095:Calcineurin Inhibitors; D018796:Immunoconjugates; D010880:Piperidines; D011743:Pyrimidines; D011758:Pyrroles; D000069594:Abatacept; C479163:tofacitinib; D053616:Janus Kinase 3; D011493:Protein Kinase C
keywords: antibody-mediated rejection; costimulation; delayed graft function; ischemia-reperfusion injury; sensitization; tolerance