title: Diagnosis and treatment considerations in a case of malignant mesenchymoma in an African fur seal (Arctocephalus pusillus).
abstract: A 20-yr-old African fur seal (Arctocephalus pusillus) presented with a slowly growing mass located on the dorsum at the level of the last thoracic vertebrae. The mass was hard, 10 cm in diameter, and not adherent to the underlying tissues. Multiple biopsies were collected for histopathology and revealed extensive areas of necrosis, small nodules of malignant mesenchymal proliferation with areas of chondroid metaplasia, and atypical cells in vessel walls. The morphologic diagnosis was suggestive of malignant mesenchymal neoplasia originating from the vascular wall. The mass was removed 1 mo later due to ulceration and infection. Histologically, based on the World Health Organization's classification of neoplastic processes in domestic animals, the tumor was consistent with malignant mesenchymoma. The margins of resection revealed the presence of neoplastic cells. Based on these results, the particular species involved, the high local invasiveness, and the high metastatic index of this malignant tumor in domestic mammals and humans, the prognosis was poor. The animal died 6 mo later with metatastic disease.
authors.affiliation: Einaudi Veterinary Center, CVIT Group, via Colaianni 23/A, Bari BA 70100 Italy. laris@libero.it
authors.forename: Pietro
authors.initials: P
authors.lastname: Laricchiuta
authors.forename: Marco
authors.initials: M
authors.lastname: Campolo
authors.forename: Paolo
authors.initials: P
authors.lastname: Martelli
authors.forename: Angela
authors.initials: A
authors.lastname: Cantore
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Menga
authors.forename: Giovanni
authors.initials: G
authors.lastname: Tortorella
authors.forename: Isidoro G
authors.initials: IG
authors.lastname: Grillo
authors.forename: Giuseppe
authors.initials: G
authors.lastname: de Ruvo
authors.forename: Donatella
authors.initials: D
authors.lastname: Gelli
authors.forename: Olimpia R
authors.initials: OR
authors.lastname: Lai
mesh_terms: D000818:Animals; D046069:Fur Seals; D008297:Male; D008637:Mesenchymoma / Q000662:veterinary*; D009361:Neoplasm Invasiveness; D019043:Vascular Neoplasms / Q000473:pathology / Q000662:veterinary*