title: Transitional cell carcinoma of the retrorectal space arisen in tailgut cyst: a case report and review of the literature.
abstract: Tailgut cysts, also known as retrorectal cystic hamartomas, are congenital lesions derived by an abnormal remnant of the postanal primitive hindgut, consisting of unilocular or multilocular cysts usually lined by squamous, transitional, or glandular epithelium. Malignant transformation is an uncommon event, and it mainly involves the neuroendocrine or glandular epithelium; other histotypes are sporadic. Here, we report, for the first time, the clinicopathological features of a transitional cell carcinoma that arose in a tailgut cyst.
authors.affiliation: 1University "Sapienza," Rome, Italy.
authors.forename: Gian Luca Rampioni
authors.initials: GL
authors.lastname: Vinciguerra
authors.forename: Paolo
authors.initials: P
authors.lastname: Mercantini
authors.forename: Marco
authors.initials: M
authors.lastname: La Torre
authors.forename: Emanuela
authors.initials: E
authors.lastname: Pilozzi
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Ziparo
authors.forename: Andrea
authors.initials: A
authors.lastname: Vecchione
mesh_terms: D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000150:complications* / Q000473:pathology*; D005260:Female; D006222:Hamartoma / Q000150:complications* / Q000473:pathology*; D006801:Humans; D012007:Rectum / Q000473:pathology; D012187:Retroperitoneal Space / Q000473:pathology*; D012445:Sacrococcygeal Region / Q000473:pathology
keywords: retrorectal space; tailgut cyst; transitional cell carcinoma