title: Cyclization-carbonylation-cyclization coupling reaction of α,β-alkynic hydrazones with palladium(II)-bisoxazoline catalyst.
abstract: A cyclization-carbonylation-cyclization coupling reaction (CCC-coupling reaction) of α,β-alkynic hydrazones, catalyzed by (box)Pd(II) complexes, afforded symmetrical ketones bearing two pyrazole groups in good to excellent yields. This method is applicable to a broad range of substrates.
authors.affiliation: Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan.
authors.forename: Taichi
authors.initials: T
authors.lastname: Kusakabe
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sagae
authors.forename: Keisuke
authors.initials: K
authors.lastname: Kato
mesh_terms: D002384:Catalysis; D003500:Cyclization; D006834:Hydrazines / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010080:Oxazoles / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D011720:Pyrazoles / Q000737:chemistry
chemical_list: D006834:Hydrazines; D007659:Ketones; D009942:Organometallic Compounds; D010080:Oxazoles; D011720:Pyrazoles; C031280:pyrazole; D010165:Palladium