title: [Influence of dietotherapy on body composition in patients with obesity and diabetes mellitus type 2].
abstract: The aim of the study was to evaluate indexes of body composition in patients with obesity and diabetes mellitus type 2 during the application of a standard hypocaloric diet.
  
  
  METHODS
  in study were included 290 patients aged of 49 +/- 13 years. Patients were divided in two groups: 1) patients with obesity (n = 145), and 2) patients with obesity and diabetes mellitus type 2 (n = 145). Within 2 weeks, all patients received standard hypocaloric diet (1500 kcal/day). Dynamics of anthropometric parameters and indices of body composition with using of bioimpedance analyzer "Inbody 720" were investigated for all patients before and after 2 weeks of dietary intervention.
  
  
  RESULTS
  During the diet there was a positive dynamics of the anthropometric parameters, which showed the reduce of body weight and body BMI in patients of first group: from 116.9 +/- 1.8 kg to 110.9 +/- 1.7 kg (p < 0.001) and from 42.1 +/- 0.6 kg/m2 to 39.8 +/- 0.6 kg/m2 (p < 0.001), while in the second group--from 112.2 +/- 1.8 do106, mass index 6 +/- 1.6 kg (p < 0.001) and from 41.6 +/- 0.6 kg/m2 to 39.4 +/- 0.5 kg/m2 (p < 0.001), respectively, without statistically significant differences between groups. Reducing the amount of fat in first group was on average 5.6 kg; and in second--an average of 3.7 kg (p < 0.001). Changes of other components of body composition also were observed in patients: the area of visceral fat in obese patients decreased from 224.9 +/- 4.5 cm2 up to 209.4 +/- 4.7 cm2 (p < 0.001) in patients with type 2 diabetes--from 237.6 +/- 4.2 cm3 up to 226.8 +/- 4.3 cm3 (p < 0.001). Study showed that controlled reduction of a diet caloric value can significantly decrease body weight in patients with obesity and diabetes mellitus type 2, mainly due to the fat component, and allow to reduce the risk of cardio-vascular diseases and metabolic disturbance.
authors.forename: I A
authors.initials: IA
authors.lastname: Lapik
authors.forename: Kh Kh
authors.initials: KhKh
authors.lastname: sharafetdinov
authors.forename: O A
authors.initials: OA
authors.lastname: Plotnikova
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Semenchenko
mesh_terms: D050154:Adiposity; D000328:Adult; D015992:Body Mass Index; D048909:Diabetes Complications / Q000178:diet therapy* / Q000473:pathology / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000178:diet therapy* / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000178:diet therapy* / Q000473:pathology / Q000503:physiopathology; D015431:Weight Loss