title: Eliminated risk of iodine contrast cancellation with multibin spectral CT.
abstract: This note compares the extent of contrast cancellation induced by iodinated contrast agents in energy integrating and photon counting multibin CT images. The contrast between a hypodense target and soft tissue is modeled for the two systems for a range of iodine concentrations and tube voltages. In energy integrating systems, we show that the contrast vanishes for low concentrations of iodine whereas the same effect is not seen in multibin systems. We conclude that it is the ability of multibin systems to apply weighting schemes post-acquisition that allows the operator to eliminate the risk of contrast cancellation between iodinated targets and the background.
authors.affiliation: Department of Physics, Royal Institute of Technology, SE-106 91 Stockholm, Sweden.
authors.forename: Moa
authors.initials: M
authors.lastname: Yveborg
authors.forename: Mats
authors.initials: M
authors.lastname: Persson
authors.forename: Joakim
authors.initials: J
authors.lastname: Crafoord
authors.forename: Mats
authors.initials: M
authors.lastname: Danielsson
authors.forename: Hans
authors.initials: H
authors.lastname: Bornefalk
mesh_terms: D016477:Artifacts; D003287:Contrast Media; D007455:Iodine; D012306:Risk; D059629:Signal-To-Noise Ratio; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007455:Iodine