title: Vaccinations for healthcare personnel: update on influenza, hepatitis B, and pertussis.
abstract: OBJECTIVE
  Healthcare personnel (HCP) are at risk for exposure to and transmission of potentially life-threatening vaccine preventable diseases to patients and colleagues. The Centers for Disease Control and Advisory Committee on Immunization Practices (ACIP) recommend routine influenza immunization and maintenance of immunity to hepatitis B and pertussis, among others. In this article, we aim to review recently approved influenza vaccines, as well as address some of the issues regarding hepatitis B and pertussis vaccinations in HCP.
  
  
  RESULTS
  Several new formulations of influenza vaccines are now available, including quadrivalent vaccines and non-egg-based vaccines; their use in HCP requires further study. An alarming rise in pertussis rates has led to a revision of ACIP guidelines recommending vaccination for women during each pregnancy. Persistent lack of immunity to hepatitis B after vaccine series remains a problem for many HCP.
  
  
  CONCLUSIONS
  Inactivated trivalent influenza vaccines remain the safest and most widely studied influenza vaccinations for healthcare workers. A pertussis booster in the form of Tdap is now recommended for most HCP. More studies are needed regarding the issue of nonresponders in HCP who receive the three-dose hepatitis B vaccine series, as there are some promising strategies available that may boost immune responses.
authors.affiliation: Division of Infectious Diseases, Memorial Sloan Kettering Cancer Cente, New York, New York 10065, USA. kaltsasa@mskcc.org
authors.forename: Anna
authors.initials: A
authors.lastname: Kaltsas
authors.forename: Kent
authors.initials: K
authors.lastname: Sepkowitz
mesh_terms: D003140:Communicable Disease Control / Q000379:methods; D006509:Hepatitis B / Q000517:prevention & control*; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional / Q000517:prevention & control*; D007251:Influenza, Human / Q000517:prevention & control*; D014611:Vaccination / Q000379:methods*; D014612:Vaccines / Q000008:administration & dosage*; D014917:Whooping Cough / Q000517:prevention & control*
chemical_list: D014612:Vaccines