title: [Immune reactivity of human lens structures in norm, age-related cortical and secondary opacification].
abstract: Using immunohistochemical methods, the immune reactivity of human lens epithelium and fibers to NSE, S-100 protein, Vim, alpha-SMA and EMA was studied in 10 normal persons and in 25 patients with its age-related cortical and secondary cataract. It was demonstrated that in age-related cortical and secondary cataract lens epithelium and fibers became more reactive to antibodies against NSE, S-100 protein and Vim, but showed no immunopositivity to alpha-SMA and EMA. Thus, the data obtained suggest some common pathogenetic mechanisms of age-related cortical and secondary cataract development with the formation of Adamyuk-Elschnig pearls.
authors.forename: N V
authors.initials: NV
authors.lastname: Korsakova
authors.forename: E M
authors.initials: EM
authors.lastname: Luzikova
authors.forename: O A
authors.initials: OA
authors.lastname: Shatskikh
authors.forename: A V
authors.initials: AV
authors.lastname: Hikiforova
authors.forename: N I
authors.initials: NI
authors.lastname: Larionova
mesh_terms: D000368:Aged; D000375:Aging / Q000378:metabolism* / Q000473:pathology*; D058442:Capsule Opacification / Q000378:metabolism* / Q000473:pathology*; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000378:metabolism* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009418:S100 Proteins / Q000378:metabolism; D014746:Vimentin / Q000378:metabolism
chemical_list: D009418:S100 Proteins; D014746:Vimentin