title: Portal vein thrombosis with renal cell carcinoma: a case report.
abstract: Portal vein thrombosis refers to an obstruction of blood flow in the portal vein; this rare disease can be both local and systemic. Local risk factors, accounting for about 70% of cases, can be abdominal cancers, inflammatory of infective diseases, surgical procedures or cirrhosis. A 62-year-old man, affected by hypertension and taking acetylsalicylic acid after a myocardial infarction in 1994, developed deep venous thrombosis on the right leg. Six months later the patient was admitted to the emergency unit due to abdominal pain. A CT scan revealed the presence of a complete splanchnic vein thrombosis and a primary tumor on the right kidney. The patient was treated with total parenteral nutrition and intravenous solution of heparin sodium first and then, because of occurrence of allergy, fondaparinux, with improvement of the abdominal pain. Subsequently he underwent right radical nephrectomy.
authors.affiliation: Urology Clinic, AOUI Verona, Verona, Italy.
authors.forename: Carolina
authors.initials: C
authors.lastname: D'Elia
authors.forename: Maria Angela
authors.initials: MA
authors.lastname: Cerruto
authors.forename: Alberto
authors.initials: A
authors.lastname: Molinari
authors.forename: Raffaella
authors.initials: R
authors.lastname: Piovesan
authors.forename: Francesca
authors.initials: F
authors.lastname: Cavicchioli
authors.forename: Anila
authors.initials: A
authors.lastname: Minja
authors.forename: Giovanni
authors.initials: G
authors.lastname: Novella
authors.forename: Walter
authors.initials: W
authors.lastname: Artibani
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects; D002292:Carcinoma, Renal Cell / Q000150:complications* / Q000473:pathology / Q000601:surgery; D057915:Drug Substitution; D000077425:Fondaparinux; D006493:Heparin / Q000009:adverse effects; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D010690:Phlebography / Q000379:methods; D011134:Polysaccharides / Q000008:administration & dosage; D011169:Portal Vein / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D000925:Anticoagulants; D011134:Polysaccharides; D006493:Heparin; D000077425:Fondaparinux