title: Bacteriophages for managing Shigella in various clinical and non-clinical settings.
abstract: The control of shigellosis in humans enjoys a prominent position in the history of bacteriophage therapy. d'Herelle first demonstrated the efficacy of phage therapy by curing 4 patients of shigellosis, and several subsequent studies confirmed the ability of phages to reduceShigellabased infection.Shigellaspp continue to cause millions of illnesses and deaths each year and the use of phages to control the disease in humans and the spread of the bacteria within food and water could point the way forward to the effective management of an infectious disease with global influence.
authors.affiliation: Department of Food Science and Agricultural Chemistry; Faculty of Agricultural and Environmental Sciences; McGill University; Montreal, QC Canada.
authors.forename: Lawrence D
authors.initials: LD
authors.lastname: Goodridge
keywords: bacteriophage therapy; control; food safety; shiga toxins; shigellosis