title: Epidemiological profile of Clonorchis sinensis infection in one community, Guangdong, People's Republic of China.
abstract: BACKGROUND
  Clonorchiasis caused by ingesting improperly prepared fish ranks among the most important but still neglected food-borne parasitic diseases, especially in the People's Republic of China (P.R. China). To promote the implementation of interventions efficiently, the demonstration of an epidemiological profile of Clonorchis sinensis infection is essential in hyper-epidemic areas.
  
  
  METHODS
  In one community with higher levels of economic development in Guangdong province, P.R. China, villagers were motivated to provide stool samples for examining helminth eggs. Then, those infected with C. sinensis completed the structured questionnaire including demographical characteristics, knowledge and behavior.
  
  
  RESULTS
  A total of 293 villagers infected with C. sinensis participated in questionnaire investigation. Among them, 94.54% were adult and 93.17% were indigenous. The geometric mean of C. sinensis eggs per gram of feces in the children, adult females and adult males was 58, 291 and 443, respectively. The divergence between knowledge and behavior in the adults, especially the adult males, was shown. Out of 228 persons eating raw fish, 160 did it more frequently at restaurants, the proportion of which varied in different populations, showing 25.00%, 54.88% and 80.28% in the children, adult females and adult males, respectively.
  
  
  CONCLUSIONS
  Different interventions need to be adopted in different populations. Chemotherapy should be prioritized in the adults, especially the adult males. In addition, health education targeting the children, is essential and may play a crucial role in controlling clonorchiasis in the long term. In order to successfully control clonorchiasis, intervention in the restaurant should not be overlooked in some endemic areas.
authors.affiliation: National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People's Republic of China.
authors.forename: Men-Bao
authors.initials: MB
authors.lastname: Qian
authors.forename: Ying-Dan
authors.initials: YD
authors.lastname: Chen
authors.forename: Yue-Yi
authors.initials: YY
authors.lastname: Fang
authors.forename: Tan
authors.initials: T
authors.lastname: Tan
authors.forename: Ting-Jun
authors.initials: TJ
authors.lastname: Zhu
authors.forename: Chang-Hai
authors.initials: CH
authors.lastname: Zhou
authors.forename: Guo-Fei
authors.initials: GF
authors.lastname: Wang
authors.forename: Long-Qi
authors.initials: LQ
authors.lastname: Xu
authors.forename: Xiao-Nong
authors.initials: XN
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D002648:Child; D002681:China / Q000453:epidemiology; D003003:Clonorchiasis / Q000188:drug therapy / Q000453:epidemiology* / Q000517:prevention & control; D003004:Clonorchis sinensis / Q000302:isolation & purification*; D005243:Feces / Q000469:parasitology; D005260:Female; D005517:Foodborne Diseases / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology / Q000517:prevention & control; D006266:Health Education; D006801:Humans; D008297:Male; D008875:Middle Aged; D010270:Parasite Egg Count; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D000871:Anthelmintics