title: Hypomethylation marks enhancers within transposable elements.
abstract: Transposable elements (TEs) make up 50% of the human genome and are usually considered a mutational burden. A new study uses signatures of DNA hypomethylation to identify tissue-specific enhancers within TEs, providing fresh evidence that mobile DNA has a non-negligible role in genome regulation and evolution.
authors.forename: Zohar
authors.initials: Z
authors.lastname: Mukamel
authors.forename: Amos
authors.initials: A
authors.lastname: Tanay
mesh_terms: D019175:DNA Methylation; D004251:DNA Transposable Elements / Q000235:genetics*; D004742:Enhancer Elements, Genetic / Q000235:genetics*; D006801:Humans; D005810:Multigene Family / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements