title: Feline viral papillomatosis: ABCD guidelines on prevention and management.
abstract: BACKGROUND
  Papillomaviruses are epitheliotropic and cause cutaneous lesions in man and several animal species, including cats.
  
  
  BACKGROUND
  Cats most likely become infected through lesions or abrasions of the skin. Species-specific viruses have been detected but human and bovine related sequences have also been found, suggesting cross-species transmission.
  
  
  METHODS
  In cats, papillomaviruses are associated with four different skin lesions: hyperkeratotic plaques, which can progress into Bowenoid in situ carcinomas (BISCs) and further to invasive squamous cell carcinomas (ISCCs); cutaneous fibropapillomas or feline sarcoids; and cutaneous papillomas. However, papillomaviruses have also been found in normal skin.
  
  
  METHODS
  Papillomavirus-induced skin lesions can be diagnosed by demonstration of papillomavirus antigen in biopsies of skin lesions, or detection of papillomavirus-like particles by electron microscopy and papillomavirus DNA by polymerase chain reaction (PCR).
  
  
  METHODS
  Spontaneous regression might be expected. In cases of ISCC, complete excision should be considered if possible.
authors.affiliation: European Advisory Board on Cat Diseases. h.f.egberink@uu.nl
authors.forename: Herman
authors.initials: H
authors.lastname: Egberink
authors.forename: Etienne
authors.initials: E
authors.lastname: Thiry
authors.forename: Karin
authors.initials: K
authors.lastname: Möstl
authors.forename: Diane
authors.initials: D
authors.lastname: Addie
authors.forename: Sándor
authors.initials: S
authors.lastname: Belák
authors.forename: Corine
authors.initials: C
authors.lastname: Boucraut-Baralon
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Frymus
authors.forename: Tim
authors.initials: T
authors.lastname: Gruffydd-Jones
authors.forename: Margaret J
authors.initials: MJ
authors.lastname: Hosie
authors.forename: Katrin
authors.initials: K
authors.lastname: Hartmann
authors.forename: Albert
authors.initials: A
authors.lastname: Lloret
authors.forename: Hans
authors.initials: H
authors.lastname: Lutz
authors.forename: Fulvio
authors.initials: F
authors.lastname: Marsilio
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Pennisi
authors.forename: Alan D
authors.initials: AD
authors.lastname: Radford
authors.forename: Uwe
authors.initials: U
authors.lastname: Truyen
authors.forename: Marian C
authors.initials: MC
authors.lastname: Horzinek
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000473:pathology / Q000517:prevention & control / Q000821:virology*; D002415:Cats; D010212:Papilloma / Q000517:prevention & control / Q000662:veterinary* / Q000821:virology; D027383:Papillomaviridae