title: Strategies to accelerate weaning from respiratory support.
abstract: Because mechanical ventilation is associated with severe complications in premature infants, it is important to limit its duration as much as possible. This can be accomplished by using strategies that preserve spontaneous respiration such as patient triggered and volume target ventilation. The use of respiratory stimulants and nasal CPAP or nasal IPPV after extubation are also effective and improve extubation success. A short course of systemic steroids can also expedite weaning and extubation.
authors.affiliation: Division of Neonatology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL 33101, USA. EBancalari@med.miami.edu
authors.forename: Eduardo
authors.initials: E
authors.lastname: Bancalari
authors.forename: Nelson
authors.initials: N
authors.lastname: Claure
mesh_terms: D060666:Airway Extubation; D045422:Continuous Positive Airway Pressure; D020878:Device Removal; D005865:Gestational Age; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007385:Intermittent Positive-Pressure Ventilation; D047928:Premature Birth / Q000503:physiopathology / Q000628:therapy*; D012121:Respiration, Artificial / Q000009:adverse effects / Q000379:methods*; D012129:Respiratory Function Tests; D012131:Respiratory Insufficiency / Q000503:physiopathology / Q000628:therapy*; D019141:Respiratory System Agents / Q000627:therapeutic use; D015300:Ventilator Weaning / Q000379:methods*
chemical_list: D005938:Glucocorticoids; D019141:Respiratory System Agents