title: The pattern of Tpeak-Tend and QT interval, and J wave during therapeutic hypothermia.
abstract: OBJECTIVE
  The electrocardiogram manifestations of hypothermia include J waves and prolongation of QT intervals. This study described changes in repolarization patterns during therapeutic hypothermia (TH).
  
  
  METHODS
  We measured the QTc and the interval from the peak to the end of the T wave (TpTe) from the V4 and V6 leads in 20 patients with TH. The TpTe was also expressed as a ratio to the duration of QT ([TpTe/QT]×100%), and to the corrected value for heart rate (TpTe/√RR).
  
  
  RESULTS
  The QTc became prolonged in all patients during TH. While the TpTe/√RR did not change, the ([TpTe/QTe]×100%] decreased significantly during TH. The J wave developed during TH in seven patients. With one patient, ventricular fibrillation occurred preceded by an abnormal J wave and prolonged TpTe during TH.
  
  
  CONCLUSIONS
  QTc prolongation without TpTe increase or abnormal J wave may not be arrhythmogenic during TH.
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Sun-Mi
authors.initials: SM
authors.lastname: Kim
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea. Electronic address: hwanggs@medimail.co.kr.
authors.forename: Gyo-Seung
authors.initials: GS
authors.lastname: Hwang
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Jin-Sun
authors.initials: JS
authors.lastname: Park
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Jeoung-Sook
authors.initials: JS
authors.lastname: Shin
authors.affiliation: Department of Emergency Medicine, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Gi-Woon
authors.initials: GW
authors.lastname: Kim
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Hyoung-Mo
authors.initials: HM
authors.lastname: Yang
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: So-Yeon
authors.initials: SY
authors.lastname: Choi
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Myeong-Ho
authors.initials: MH
authors.lastname: Yoon
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Joon-Han
authors.initials: JH
authors.lastname: Shin
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: Seung-Jea
authors.initials: SJ
authors.lastname: Tahk
mesh_terms: D003936:Diagnosis, Computer-Assisted; D003937:Diagnosis, Differential; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced / Q000009:adverse effects*; D008133:Long QT Syndrome / Q000175:diagnosis* / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D016896:Treatment Outcome
keywords: Cardiac arrest; Cardiopulmonary resuscitation; Induced mild hypothermia; QT interval