title: Three-channel fluorescent sensing via organic white light-emitting dyes for detection of hydrogen sulfide in living cells.
abstract: To demonstrate the feasibility of development of three-channel based fluorescent sensors based on organic white light-emitting dyes, in this work, for proof-of-principle, we initially judiciously designed an organic white light-emitting dye, which was further used as a robust platform to engineer a new fluorescent sensor for monitoring H2S with turn-on fluorescence signals in blue, green, and red emission channels in both solution and living cells. This work should open a new avenue for design of three- and multiple-channel based fluorescent sensors for various analytes.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, PR China.
authors.forename: Jiaoliang
authors.initials: J
authors.lastname: Wang
authors.forename: Weiying
authors.initials: W
authors.lastname: Lin
authors.forename: Weiling
authors.initials: W
authors.lastname: Li
mesh_terms: D000042:Absorption; D002460:Cell Line; D002470:Cell Survival; D004126:Dimethylformamide / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D006862:Hydrogen Sulfide / Q000032:analysis*; D008968:Molecular Conformation; D011522:Protons; D012997:Solvents / Q000737:chemistry; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D011522:Protons; D012997:Solvents; D004126:Dimethylformamide; D006862:Hydrogen Sulfide
keywords: Cellular imaging; ESIPT; Fluorescent sensors; Hydrogen sulphide; Three-channel