title: Darkness at the end of the tunnel: poststenotic kidney injury.
abstract: Renal artery stenosis remains an important contributor to renal failure in the elderly population, but uncertainty continues to surround the mechanisms underlying progressive renal dysfunction. Here, we present the current understanding of the pathogenic mechanisms responsible for renal injury in these patients, with emphasis on those involved in disease progression.
authors.affiliation: Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
authors.forename: Alfonso
authors.initials: A
authors.lastname: Eirin
authors.forename: Lilach O
authors.initials: LO
authors.lastname: Lerman
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000503:physiopathology; D017209:Apoptosis / Q000502:physiology; D018450:Disease Progression; D006801:Humans; D007249:Inflammation / Q000503:physiopathology; D018384:Oxidative Stress / Q000502:physiology; D012078:Renal Artery Obstruction / Q000150:complications* / Q000503:physiopathology; D051437:Renal Insufficiency / Q000209:etiology* / Q000503:physiopathology; D012084:Renin-Angiotensin System / Q000502:physiology