title: [The high content of palmitinic fatty acid in food as a major cause of increase of concentration of cholesterol and low density lipoproteins and atheromatous plaques of arteries' intima].
abstract: The positioning of individual triglycerides of blood serum in palmitinic and oleic lipoproteins ofvery low density in the order ofincrease of the rate constant of their hydrolysis under action of post-heparin lipoprotein leads to the sequence as follows: palmitoil-palmitoil-palmitate-->palmitoil-palmitoil-oleate-->palmitoil-oleil-palmitat-->oleil-palmitoil-palmitate-->oleil-palmitate-palmitate-->oleil-oleil-palmitate-->oleil-oleil-oleate. The shift to the left and to the right is discerned with this spectrum of isoforms of triglycerides. The shift to the left into direction of palmitinicc triglycerides occurs in case of eating of animal food (i.e. beef andfoodstuf of fat saw milk) when the content of palmitinic saturated fatty acid supersedes 15% of fatty acids total and under the development of endogenic syndrome of insulin resistance. The content of low density lipoproteins cholesterol is high in blood The shift to the right with prevalence of oleinic triglycerides occurs in case of low content of beef and foodstuff of fat saw milk in food, fish eating, seafood and olive oil. The physiologic levels of carbohydrates in food and insulin function are present too. The shift to the right initiates the action of insulin, ometa-3 essential polyenic fatty acids, glytazones and fibrates. They increase the activity of delta9-stearil-KoA-desaturase-2 and the transformation of palmitine saturated fatty acid into mono unsaturated oleinic fatty acid. The shift to the left forms the palmitine alternative of metabolism of substrate to supply cells with energy. The shift to the right is a more effective oleinic alternative.
authors.forename: V N
authors.initials: VN
authors.lastname: Titov
mesh_terms: D000818:Animals; D001711:Biotransformation; D002784:Cholesterol / Q000097:blood*; D004041:Dietary Fats / Q000009:adverse effects* / Q000032:analysis / Q000378:metabolism; D007328:Insulin / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood*; D019308:Palmitic Acid / Q000009:adverse effects* / Q000032:analysis / Q000378:metabolism; D010802:Phylogeny; D058226:Plaque, Atherosclerotic / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D017539:Tunica Intima / Q000187:drug effects* / Q000473:pathology
chemical_list: D004041:Dietary Fats; D007328:Insulin; D008077:Lipoproteins, LDL; D019308:Palmitic Acid; D002784:Cholesterol