title: Dextran sodium sulfate-induced murine inflammatory colitis model.
abstract: Colitis is a chronic inflammatory disease of the colon that is characterized by recurring, acute episodes. Mouse models of colitis allow for the study of multiple aspects of this disease, including the innate immune response, epithelial and intestinal cell response, and wound healing. The following protocols cover acute, chronic, and cancer-associated colitis models.
authors.affiliation: Infectious and Inflammatory Disease Center, Sanford Burnham Medical Research Institute, La Jolla, CA, USA.
authors.forename: Monika
authors.initials: M
authors.lastname: Schneider
mesh_terms: D000818:Animals; D003092:Colitis / Q000139:chemically induced / Q000150:complications / Q000276:immunology / Q000473:pathology*; D016264:Dextran Sulfate / Q000008:administration & dosage* / Q000633:toxicity; D004195:Disease Models, Animal; D006801:Humans; D007113:Immunity, Innate; D015212:Inflammatory Bowel Diseases / Q000139:chemically induced / Q000276:immunology / Q000473:pathology; D051379:Mice; D009369:Neoplasms / Q000150:complications / Q000473:pathology*
chemical_list: D016264:Dextran Sulfate