title: High-dose tamoxifen in breast cancer bone metastasis.
abstract: High-dose tamoxifen was used as a treatment for bone metastasis in 16 patients with breast cancer. All of them had been pretreated with hormonal therapy, including lowdose tamoxifen. The results were extremely positive with clinical amelioration and also disappearance of osteolysis in 5 patients.
authors.affiliation: First Oncology Clinic, Errikos Dunant Hospital, Athens, Greece.
authors.forename: G P
authors.initials: GP
authors.lastname: Stathopoulos
authors.forename: D
authors.initials: D
authors.lastname: Trafalis
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000556:secondary; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008875:Middle Aged; D020845:Selective Estrogen Receptor Modulators / Q000008:administration & dosage*; D013629:Tamoxifen / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D020845:Selective Estrogen Receptor Modulators; D013629:Tamoxifen