title: Catatonia and parkinsonism as a sequelae of typhoid fever: a rare experience.
abstract: Although neurological manifestations of typhoid fever was thought to be obsolete from modern world, emergence of multidrug resistant typhoid bacilli and reporting of outbreak of typhoid fever with a range of early neuropsychiatric manifestations from various parts of world has led clinicians and investigators to re-evaluate the clinical spectrum of this endemic sinister disease. An 18-year-old male student was admitted in psychiatry ward with mutism, staring look, posturing and rigidity. There was history of typhoid fever 1 week before for which he was prescribed cefuroxime. Although investigations fail to provide any clue, his catatonic symptoms disappeared 2 weeks later giving way to resting tremor, bradykinesia, cog-wheel rigidity but without gait abnormality. He was successfully treated with lorazepam, amantidine, olanzapine and pramiprexole. The patient was asymptomatic within a month. He had no recurrence of symptoms till last follow-up, 6 months from the illness.
authors.affiliation: Department of Psychiatry, NRS Medical College Hospital, Kolkata, West Bengal, India. arka_talukdar@yahoo.com
authors.forename: Payel
authors.initials: P
authors.lastname: Talukdar
authors.forename: Arghya
authors.initials: A
authors.lastname: Dutta
authors.forename: Sukriti
authors.initials: S
authors.lastname: Rana
authors.forename: Arunansu
authors.initials: A
authors.lastname: Talukdar
mesh_terms: D000293:Adolescent; D000547:Amantadine / Q000627:therapeutic use; D000978:Antiparkinson Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001569:Benzodiazepines / Q000627:therapeutic use; D052160:Benzothiazoles / Q000627:therapeutic use; D002389:Catatonia / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D008140:Lorazepam / Q000627:therapeutic use; D008297:Male; D000077152:Olanzapine; D020734:Parkinsonian Disorders / Q000188:drug therapy / Q000209:etiology*; D000077487:Pramipexole; D014435:Typhoid Fever / Q000150:complications*
chemical_list: D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D052160:Benzothiazoles; D006993:Hypnotics and Sedatives; D001569:Benzodiazepines; D000077487:Pramipexole; D000547:Amantadine; D000077152:Olanzapine; D008140:Lorazepam