title: [Fundamental bases of search of medicines for therapy of a diabetes mellitus type 2].
abstract: In the presented review the data on searching for new drugs for diabetes mellitus treantment are analyzed. These drugs are used for metabolic disorder correction leading to hyperglycemia: beta-cells dysfunction, peripheral insulin resistance, increased hepatic glucose output.
authors.forename: A A
authors.initials: AA
authors.lastname: Spasov
authors.forename: V I
authors.initials: VI
authors.lastname: Petrov
authors.forename: N I
authors.initials: NI
authors.lastname: Chepliaeva
authors.forename: K V
authors.initials: KV
authors.lastname: Lenskaia
mesh_terms: D000911:Antibodies, Monoclonal / Q000494:pharmacology; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D055808:Drug Discovery; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D007328:Insulin / Q000378:metabolism; D007333:Insulin Resistance; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects / Q000503:physiopathology; D008099:Liver / Q000187:drug effects / Q000378:metabolism
chemical_list: D000911:Antibodies, Monoclonal; D007004:Hypoglycemic Agents; D007328:Insulin; D005947:Glucose