title: Efficient preparation of 4-hydroxyquinolin-2(1H)-one derivatives with silver-catalyzed carbon dioxide incorporation and intramolecular rearrangement.
abstract: Although 4-hydroxyquinolin-2(1H)-one derivatives have attracted much attention due to their biological benefits, conventional reactions under harsh heat conditions must be employed to provide these key compounds. In the presence of a catalytic amount of silver salt, various o-alkynylanilines were treated with carbon dioxide and a base under mild reaction conditions to afford the corresponding 4-hydroxyquinolin-2(1H)-one derivatives in high yield.
authors.affiliation: Department of Chemistry, Keio University, 3-14-1 Hiyoshi, Yokohama, 223-8522, Japan.
authors.forename: Tomonobu
authors.initials: T
authors.lastname: Ishida
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kikuchi
authors.forename: Tohru
authors.initials: T
authors.lastname: Yamada
mesh_terms: D002245:Carbon Dioxide / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D015363:Quinolones / Q000138:chemical synthesis* / Q000737:chemistry; D012834:Silver / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: C586058:4-hydroxyquinolin-2(1H)-one; D015363:Quinolones; D002245:Carbon Dioxide; D012834:Silver