title: RAP1: protector of telomeres, defender against obesity.
abstract: Telomere dysfunction has previously been linked to metabolic disorders. In this issue of Cell Reports, Martínez et al. (2013) and Yeung et al. (2013) now extend this link, demonstrating that deletion of the telomere binding protein RAP1 leads to obesity and insulin resistance.
authors.affiliation: Huffington Center on Aging and Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
authors.forename: MyLinh T
authors.initials: MT
authors.lastname: Duong
authors.forename: Ergün
authors.initials: E
authors.lastname: Sahin
mesh_terms: D000818:Animals; D001835:Body Weight / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000235:genetics*; D016615:Telomere / Q000378:metabolism*; D034501:Telomere-Binding Proteins / Q000235:genetics*; D020827:rap1 GTP-Binding Proteins / Q000378:metabolism*
chemical_list: D034501:Telomere-Binding Proteins; D020827:rap1 GTP-Binding Proteins