title: The effect of Helicobacter pylori on vitamin B 12 blood levels in chronic renal failure patients: a single blind control trial.
abstract: Helicobacter pylori (HP) is a common infection worldwide and has been associated with severe morbidity. The level of vitamin B 12 in HP-infected chronic kidney disease (CKD) patients is reported to be lower than in the general population. The present study has been designed to evaluate the vitamin B 12 level in HP-infected CKD patients. We assessed the serum levels of vitamin B 12 in 50 CKD patients with positive HP serology, one and three months after the eradication of HP infection. There were significant differences between the serum levels of vitamin B 12 in the study patients before (806.98 ± 466.82) and after (760.36 ± 433.93) eradication treatment (P <0.001). We conclude that our study suggests the correlation between vitamin B 12 deficiency in CKD patients and the HP infection status.
authors.affiliation: Baqiyatallah University of Medical Sciences, Tehran, Iran. Khedmat.h@gmail.com
authors.forename: Hossein
authors.initials: H
authors.lastname: Khedmat
authors.forename: Mohsen
authors.initials: M
authors.lastname: Amini
authors.forename: Ashraf
authors.initials: A
authors.lastname: Karbasi
authors.forename: Reza
authors.initials: R
authors.lastname: Azizi
mesh_terms: D005260:Female; D016481:Helicobacter Infections / Q000097:blood* / Q000150:complications; D016480:Helicobacter pylori; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000150:complications; D008297:Male; D008875:Middle Aged; D016037:Single-Blind Method; D014805:Vitamin B 12 / Q000097:blood*
chemical_list: D014805:Vitamin B 12