title: 3-[(2-chloroquinolin-3-yl)methyl]quinazolin-4(3H)-ones as potential larvicidal agents.
abstract: The larvicidal effect of series of 3-[(2-chloroquinolin-3-yl)methyl] uinazolin-4(3H)-ones, 5a-e, against Chironomus tentans Fabricius has been investigated. The results showed that tested compounds demonstrated strong larvicidal activity, and caused high percentage of mortality after 24 h at the doses of 40-100 g/ml, especially in the case of 3-[(2-chloro-8-methyquinolin-3-yl)methyl]quinazolin-4(3H)-one, 5b, that act as a promising larvicidal agent.
authors.affiliation: School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, India.
authors.forename: Selvaraj Mohana
authors.initials: SM
authors.lastname: Roopan
authors.forename: Fazlur-Rahman Nawaz
authors.initials: FR
authors.lastname: Khan
authors.forename: Jong Sung
authors.initials: JS
authors.lastname: Jin
mesh_terms: D000818:Animals; D002683:Chironomidae; D007306:Insecticides / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D011799:Quinazolines / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D007306:Insecticides; D011799:Quinazolines