title: The association between glucose challenge test level and fetal nutritional status.
abstract: OBJECTIVE
  To examine the relationship between maternal glucose challenge test (GCT) levels and fetal nutritional status index (FNSI: a ratio of child's birth weight (kg) over squared maternal height (m(2)).
  
  
  METHODS
  A total of 2193 women from the Beichen district, Tianjin, China, who had 50 g GCT at gestational age 24-28 weeks, gave a full-term singleton birth between June 2011 and October 2012, and with both maternal height and birth weight measures are included in this report.
  
  
  RESULTS
  Approximately 28.0% of women had a GCT ≥ 7.8 mmol/L. The newborns of mothers with a GCT ≥ 7.8 mmol/L had significantly higher level of FNSI ([kg/m(2)], boys: 1.336 versus 1.296, p < 0.001; girls: 1.312 versus 1.268, p < 0.0001). Logistic regression results, after adjustment for maternal age, residence, education, nationality, history of disease and reproduction, insurance and gestational age, indicated that every unit increase in FNSI was associated with approximately threefold higher odds (OR [95% CI]: 3.6 [1.5, 8.9]) of being in GCT ≥ 7.8 mmol/L for women giving birth as boys and fivefold higher odds (5.9 [2.5, 14.1]) for giving birth as girls.
  
  
  CONCLUSIONS
  Women with a GCT ≥ 7.8 mmol/L have babies with a higher FNSI, suggesting that these infants may be overnourished before birth and may increase cardiovascular risk in their future.
authors.affiliation: Tianjin Women and Children's Health Center , Tianjin , China .
authors.forename: J Junhong
authors.initials: JJ
authors.lastname: Leng
authors.forename: Gongshu
authors.initials: G
authors.lastname: Liu
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Weiqin
authors.initials: W
authors.lastname: Li
authors.forename: Huihuan
authors.initials: H
authors.lastname: Liu
authors.forename: Ye
authors.initials: Y
authors.lastname: She
authors.forename: Jian
authors.initials: J
authors.lastname: Liu
mesh_terms: D000328:Adult; D001724:Birth Weight; D001786:Blood Glucose / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000209:etiology; D005260:Female; D005333:Fetus / Q000502:physiology*; D005951:Glucose Tolerance Test; D006305:Health Status Indicators; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009752:Nutritional Status; D010865:Pilot Projects; D011247:Pregnancy; D011263:Pregnancy Trimester, Third / Q000097:blood; D039401:Prenatal Nutritional Physiological Phenomena; D012307:Risk Factors; D055815:Young Adult
chemical_list: D001786:Blood Glucose