title: An overview of respiratory problems in children with Down's syndrome.
abstract: Respiratory disease is a common cause of morbidity and mortality in children with Down's syndrome (DS). Causes range from those problems common to many children with DS, such as a narrow airway or impaired immunity, to rare structural lesions, such as tracheal bronchus. Additionally, other organ systems or extrinsic factors may play a role. A thorough understanding of the range of potential problems will aid in the evaluation and management of children with DS and respiratory symptoms.
authors.affiliation: PICU and Respiratory Medicine, Nottingham University Hospital, , Nottingham, UK.
authors.forename: Rachel
authors.initials: R
authors.lastname: Watts
authors.forename: H
authors.initials: H
authors.lastname: Vyas
mesh_terms: D002648:Child; D004314:Down Syndrome / Q000150:complications*; D006801:Humans; D015994:Incidence; D012140:Respiratory Tract Diseases / Q000150:complications* / Q000453:epidemiology