title: Synthesis of calothrixins and its analogs using FeCl3-mediated domino reaction protocol.
abstract: A novel one pot synthesis of calothrixin B and its analogs is achieved involving an FeCl3-mediated domino reaction of enamines in dry DMF at reflux. Alternatively, the enamines upon interaction with CuBr2 in DMF at reflux led to the formation of 1-phenylsulfony-2-(2'-nitroaryl)-4-hydroxycarbazole-3-carbaldehydes in excellent yields.
authors.affiliation: Department of Organic Chemistry, School of Chemistry, University of Madras, Guindy Campus Chennai 600 025, Tamil Nadu, India.
authors.forename: Bose Muthu
authors.initials: BM
authors.lastname: Ramalingam
authors.forename: Velu
authors.initials: V
authors.lastname: Saravanan
authors.forename: Arasambattu K
authors.initials: AK
authors.lastname: Mohanakrishnan
mesh_terms: D002227:Carbazoles / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D026121:Indole Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D002227:Carbazoles; D002712:Chlorides; D005290:Ferric Compounds; D026121:Indole Alkaloids; C418327:calothrixin B; C024555:ferric chloride