title: Seizure risk factors in shunted hydrocephalic patients.
abstract: OBJECTIVE
  There are controversies about seizure risk factors in shunted hydrocephalic patients which can be due to having merged two different types of seizure (preshunt and postshunt seizures) in previous studies. Also, it is not known whether a considerable change in ventricular size after shunting can be a risk factor of postshunt seizures.
  
  
  METHODS
  150 hydrocephalic patients who underwent shunting from 2006 to 2011 in the Children's Hospital Medical Center in Tehran, Iran, were visited at least 1 year after shunting to assess risk factors of preshunt and postshunt seizures. Ventricular size was assessed by using a radiologic index of bifrontal ratio (BFR).
  
  
  RESULTS
  Preshunt seizures were higher in patients with postinfectious hydrocephalus and intraventricular hemorrhage. Early shunting, history of shunt complications and shunt infection, and a high number of shunt revisions were significant risk factors for developing postshunt seizures. The change in BFR after shunting was not a significant risk factor of postshunt seizures.
  
  
  CONCLUSIONS
  The difference between risk factors of preshunt seizures and postshunt seizures shows that they are two different types of seizures with different natures. Preshunt seizures are hard to prevent as they are related to the underlying disease of the brain or the etiology of hydrocephalus. However, postshunt seizures are related to the shunt and might be decreased by preventing shunt complications.
authors.affiliation: Department of Neurosurgery, Children's Hospital Medical Center, Tehran University of Medical Science, Tehran, Iran.
authors.forename: Masoud
authors.initials: M
authors.lastname: Majed
authors.forename: Yasir
authors.initials: Y
authors.lastname: Andrabi
authors.forename: Farideh
authors.initials: F
authors.lastname: Nejat
authors.forename: Mostafa
authors.initials: M
authors.lastname: El Khashab
mesh_terms: D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects*; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus / Q000453:epidemiology* / Q000601:surgery*; D007223:Infant; D007492:Iran / Q000453:epidemiology; D008297:Male; D012307:Risk Factors; D012640:Seizures / Q000175:diagnosis* / Q000453:epidemiology*