title: Blood parameters changes in cord blood of newborns of hypertensive mothers.
abstract: The aim of this study was to investigate the changes in the peripheral blood of newborns of hypertensive mothers. The umbilical cord blood from newborns of 31 hypertensive mothers and 32 healthy mothers were examined. In all subjects, complete blood count, peripheral blood smear, reticulocyte count, vitamin B12, folate, ferritin levels and hemoglobin electrophoresis were performed. The subjects were followed up on for 1 year in terms of infections. RBC, hemoglobin, reticulocyte count and normoblast count were higher in the newborns of hypertensive mothers compared to the control group, and total leukocytes, neutrophil, lymphocyte, monocyte, eosinophil, and thrombocyte counts were lower. The number of neutropenic and thrombocytopenic subjects in newborns of hypertensive mothers was higher compared to the control group. On peripheral smears, dysplastic changes in neutrophils and erythrocytes were observed with a higher rate in newborns of hypertensive mothers compared to the control group. HbF levels were found to be higher in newborns of hypertensive mothers compared to the control group. During the follow-up period of 1 year, the number of infections in newborns of hypertensive mothers was found to be higher than the control group.
  
  
  CONCLUSIONS
  Newborns of hypertensive mothers should be carefully evaluated and monitored in terms of hematologic abnormalities. Complete blood counts and peripheral blood smears can be used as significant parameters for early diagnosis of possible complications.
authors.affiliation: Department of Pediatrics, Gulhane Military Medical Academy and Medical Faculty, Ankara, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Bolat
authors.forename: Orhan
authors.initials: O
authors.lastname: Gursel
authors.forename: Emin
authors.initials: E
authors.lastname: Kurekci
authors.forename: Avni
authors.initials: A
authors.lastname: Atay
authors.forename: Okan
authors.initials: O
authors.lastname: Ozcan
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001772:Blood Cell Count; D016022:Case-Control Studies; D004909:Erythrocyte Indices; D005260:Female; D005293:Ferritins / Q000097:blood; D005312:Fetal Blood / Q000378:metabolism*; D005500:Follow-Up Studies; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D046110:Hypertension, Pregnancy-Induced; D007231:Infant, Newborn; D016015:Logistic Models; D008297:Male; D011247:Pregnancy; D017701:Reticulocyte Count; D014805:Vitamin B 12 / Q000097:blood
chemical_list: D015415:Biomarkers; D006454:Hemoglobins; D005293:Ferritins; D014805:Vitamin B 12