title: ST-segment elevation associated with allergic reaction to echocardiographic contrast agent administration.
abstract: We report a case of an allergic reaction after the administration of an echocardiographic contrast agent which resulted in ST-segment elevation. Hypersensitivity and allergic reactions are known causes of acute cardiovascular events. However, only limited reports are available which suggest the exact mechanism of the occurrence of angina or myocardial infarction during severe allergic reactions. In our case, through invasive imaging (coronary angiography and IVUS) we have shown for the first time a transient coronary spasm in the absence of intra-coronary thrombus and only minimal neointimal hyperplasia.
authors.affiliation: Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333, ZA, Leiden, the Netherlands.
authors.forename: Ag
authors.initials: A
authors.lastname: van Ginkel
authors.forename: Bj
authors.initials: B
authors.lastname: Sorgdrager
authors.forename: M A
authors.initials: MA
authors.lastname: de Graaf
authors.forename: I
authors.initials: I
authors.lastname: Karalis
authors.forename: N
authors.initials: N
authors.lastname: Ajmone Marsan