title: Moderate and severe traumatic brain injury: pathophysiology and management.
abstract: Traumatic brain injury (TBI) is a serious disorder that is all too common. TBI ranges in severity from mild concussion to a severe life-threatening state. Across this spectrum, rational therapeutic approaches exist. Early identification that TBI has occurred in a patient is paramount to optimal outcome. Proper clinical management should be instituted as soon as possible by appropriately trained medical providers. More seriously injured patients must be triaged to advanced care centers. It is only through this rational approach to TBI that patients may expect to achieve optimal clinical and functional outcome.
authors.affiliation: Division of Neurocritical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions, 600 N. Wolfe St, Baltimore, MD 21287, USA.
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Frattalone
authors.forename: Geoffrey S F
authors.initials: GS
authors.lastname: Ling
mesh_terms: D001930:Brain Injuries / Q000503:physiopathology / Q000628:therapy*; D003422:Critical Care / Q000379:methods*; D042241:Early Diagnosis; D006801:Humans; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome