title: Parenchymal brain oxygen monitoring in the neurocritical care unit.
abstract: Patients admitted to the neurocritical care unit (NCCU) often have serious conditions that can be associated with high morbidity and mortality. Pharmacologic agents or neuroprotectants have disappointed in the clinical environment. Current NCCU management therefore is directed toward identification, prevention, and treatment of secondary cerebral insults that evolve over time and are known to aggravate outcome. This strategy is based on a variety of monitoring techniques including use of intraparenchymal monitors. This article reviews parenchymal brain oxygen monitors, including the available technologies, practical aspects of use, the physiologic rationale behind their use, and patient management based on brain oxygen.
authors.affiliation: The Brain and Spine Center, Lankenau Medical Center, 100 E. Lancaster Ave, Wynnewood, PA 19096, USA. lerouxp@mlhs.org
authors.forename: Peter D
authors.initials: PD
authors.lastname: Le Roux
authors.forename: Mauro
authors.initials: M
authors.lastname: Oddo
mesh_terms: D015415:Biomarkers / Q000097:blood; D001930:Brain Injuries / Q000378:metabolism / Q000628:therapy*; D003422:Critical Care / Q000379:methods; D006801:Humans; D010100:Oxygen / Q000378:metabolism*; D013345:Subarachnoid Hemorrhage / Q000378:metabolism / Q000601:surgery
chemical_list: D015415:Biomarkers; D010100:Oxygen