title: [Mechanical thrombectomy in the treatment of acute disturbance of cerebral circulation].
abstract: An essential aim of acute treatment of brain infarction is to restrict the size of the infarct by rapid and permanent recanalization of the obstructed artery. Thrombolytic therapy based on intravenous administration of alteplas (IV-tPA) exhibits the highest efficacy in the treatment of cerebral artery thrombi that are fairly small or intermediate in size. Intra-arterial thrombolysis (IA-tPA) and mechanical thrombectomy can be considered, if IV-tPA turns out to be ineffective or is contraindicated. In situations where the expected effect of IV-tPA:n is modest per se, mechanical thrombectomy should be taken into account as part of the therapeutic strategy.
authors.affiliation: PSHP Kuvantamiskeskus.
authors.forename: Juha-Pekka
authors.initials: JP
authors.lastname: Pienimäki
authors.forename: Jyrki
authors.initials: J
authors.lastname: Ollikainen
authors.forename: Veikko
authors.initials: V
authors.lastname: Kähärä
authors.forename: Janne
authors.initials: J
authors.lastname: Seppänen
authors.forename: Heikki
authors.initials: H
authors.lastname: Numminen
mesh_terms: D002544:Cerebral Infarction / Q000628:therapy*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D061185:Mechanical Thrombolysis / Q000379:methods*; D015912:Thrombolytic Therapy / Q000379:methods*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator