title: Clonal mast cell activation syndrome with anaphylaxis to sulfites.
abstract: Sulfites are rarely suspected as causative agents of immediate-type hypersensitivity. We report on a 49-year-old male patient who developed recurrent severe hypotension after food ingestion. A diagnosis of monoclonal mast cell activation syndrome was established. In the double-blind, placebo-controlled food challenge, the patient reacted to potassium metabisulfite with anaphylaxis.
authors.affiliation: Department of Dermatology and Allergy Biederstein, Technical University Munich, Munich, Germany.
authors.forename: Liliana
authors.initials: L
authors.lastname: Cifuentes
authors.forename: Johannes
authors.initials: J
authors.lastname: Ring
authors.forename: Knut
authors.initials: K
authors.lastname: Brockow
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced* / Q000150:complications*; D049109:Cell Proliferation; D002999:Clone Cells; D005512:Food Hypersensitivity / Q000175:diagnosis; D006801:Humans; D008297:Male; D008407:Mast Cells / Q000166:cytology / Q000473:pathology*; D008415:Mastocytosis / Q000150:complications / Q000209:etiology* / Q000276:immunology; D008875:Middle Aged; D010919:Placebos; D013447:Sulfites / Q000276:immunology*; D013577:Syndrome
chemical_list: D010919:Placebos; D013447:Sulfites; C005199:potassium metabisulfite