title: Treatment regimens, protocols, dosage, and indications for UVA1 phototherapy: facts and controversies.
abstract: During the last three decades, ultraviolet A1 (UVA1) phototherapy has emerged as a specific phototherapeutic modality with distinct modes of action and some well established indications. Atopic dermatitis, localized scleroderma, and systemic lupus erythematosus seem to be the conditions with the best evidence regarding efficacy and safety of UVA1 phototherapy. Further indications for UVA1 include subacute prurigo, lichen sclerosus, dyshidrotic dermatitis, cutaneous T cell lymphoma, urticaria pigmentosa, and pityriasis rosea; nevertheless, there are some unknowns, uncertainties, and controversies concerning short- and long-term side effects, efficacy and dosage regimens of UVA1 phototherapy in some conditions. We describe and discuss treatment regimens, protocols, dosage, and indications for UVA1 phototherapy.
authors.affiliation: Department of Dermatology, Venereology, and Allergology at Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany. Electronic address: t.gambichler@klinikum-bochum.de.
authors.forename: Thilo
authors.initials: T
authors.lastname: Gambichler
authors.affiliation: Department of Dermatology, Venereology, and Allergology at Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.
authors.forename: Sarah
authors.initials: S
authors.lastname: Terras
authors.affiliation: Department of Dermatology, Venereology, and Allergology at Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Kreuter
mesh_terms: D003876:Dermatitis, Atopic / Q000628:therapy; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000628:therapy; D008180:Lupus Erythematosus, Systemic / Q000628:therapy; D010789:Phototherapy; D017410:Practice Guidelines as Topic; D011879:Radiotherapy Dosage; D012594:Scleroderma, Localized / Q000628:therapy; D012871:Skin Diseases / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome; D014467:Ultraviolet Therapy / Q000009:adverse effects / Q000379:methods*; D014582:Urticaria Pigmentosa / Q000628:therapy