title: Docetaxel (Taxotere®)-induced cavitary change of pulmonary metastatic lesions complicated by bilateral spontaneous pneumothoraces in a patient with primary adenocarcinoma of the lung.
abstract: Pneumothorax is a complication that rarely occurs after chemotherapy for lung cancer. We report the chest computed tomography findings of a case of spontaneous pneumothorax complicating docetaxel (Taxotere®) treatment for pulmonary metastasis in a 70-year-old woman with pulmonary adenocarcinoma. The patient developed bilateral pneumothoraces, which was induced by changes in the cavitary pulmonary metastatic lesions, after systemic chemotherapy with docetaxel. The chest computed tomography findings and possible mechanisms of this unusual complication are discussed in this report.
authors.affiliation: Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, 325, Sec 2, Chenggong Road, Neihu District, Taipei 11490, Taiwan. m870877@ndmctsgh.edu.tw
authors.forename: Hao-Lun
authors.initials: HL
authors.lastname: Kao
authors.forename: Wen-Chiung
authors.initials: WC
authors.lastname: Lin
authors.forename: Hsian-He
authors.initials: HH
authors.lastname: Hsu
authors.forename: Guo-Shu
authors.initials: GS
authors.lastname: Huang
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000077143:Docetaxel; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D009362:Neoplasm Metastasis; D011030:Pneumothorax / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D043823:Taxoids / Q000009:adverse effects / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D043823:Taxoids; D000077143:Docetaxel