title: [The actual aspects of evaluation of proliferation and apoptosis in clinical laboratory diagnostic: a review].
abstract: The article deals with the issues of studying cell proliferation and apoptosis, relationship and conditionality of these two important physiologic processes. The main cytological markers of proliferation and apoptosis are analyzed, including the techniques of intravital non-invasive visualization of apoptosis. The value of these markers in clinical laboratory diagnostic and investigation is considered. The mechanisms of action of antineoplastic pharmaceuticals and issues of choosing the optimal scheme of treatment are analyzed.
mesh_terms: D017209:Apoptosis / Q000235:genetics*; D015415:Biomarkers / Q000737:chemistry / Q000378:metabolism; D049109:Cell Proliferation; D019411:Clinical Laboratory Techniques / Q000379:methods*; D004247:DNA / Q000032:analysis* / Q000737:chemistry; D006801:Humans
chemical_list: D015415:Biomarkers; D004247:DNA