title: Long-acting neuromuscular blocker use during prehospital transport of trauma patients.
abstract: BACKGROUND
  The purpose of this study was to determine the rate of long-acting neuromuscular blocker (LA-NMB) use and evaluate the concurrent use of sedatives during prehospital care.
  
  
  METHODS
  Prehospital patients who were brought to a single emergency department in the United States.
  
  
  METHODS
  This was a retrospective cohort study of trauma patients who were intubated in the prehospital setting. The primary outcome measure was to determine the rate of LA-NMB use. The use of postintubation sedatives and the time to the administration of sedative agents was compared between patients who received an LA-NMB and those who did not.
  
  
  RESULTS
  A total of 51 patients were included in the final analyses. Overall, 82% (n = 42) of patients received an LA-NMB during transport. There was no difference in the rate of postintubation sedative use during transport between the LA-NMB and no LA-NMB groups (79% vs. 67%, respectively, P = .42). The LA-NMB group received sedatives less promptly after intubation compared with those who did not receive LA-NMBs (16 vs. 7 minutes, respectively; P = .04).
  
  
  CONCLUSIONS
  The use of LA-NMB is common during the prehospital transport of trauma patients. Some of these patients may not be given sedatives or may have delays in receiving sedatives after intubation.
authors.affiliation: College of Pharmacy, The Ohio State University Wexner Medical Center, Hilliard, OH, USA.
authors.forename: Kathryn A
authors.initials: KA
authors.lastname: Elofson
authors.forename: Sarah F
authors.initials: SF
authors.lastname: Rhoads
authors.forename: Andrew
authors.initials: A
authors.lastname: Tang
authors.forename: Joshua B
authors.initials: JB
authors.lastname: Gaither
authors.forename: Asad E
authors.initials: AE
authors.lastname: Patanwala
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000732:Androstanols / Q000627:therapeutic use; D015331:Cohort Studies; D004632:Emergency Medical Services / Q000379:methods*; D005045:Etomidate / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D007442:Intubation, Intratracheal / Q000379:methods*; D008297:Male; D008874:Midazolam / Q000627:therapeutic use; D008875:Middle Aged; D009466:Neuromuscular Blocking Agents / Q000627:therapeutic use*; D012189:Retrospective Studies; D000077123:Rocuronium; D013390:Succinylcholine / Q000627:therapeutic use; D014187:Transportation of Patients / Q000379:methods; D014673:Vecuronium Bromide / Q000627:therapeutic use; D014947:Wounds and Injuries; D055815:Young Adult
chemical_list: D000732:Androstanols; D006993:Hypnotics and Sedatives; D009466:Neuromuscular Blocking Agents; D014673:Vecuronium Bromide; D013390:Succinylcholine; D008874:Midazolam; D000077123:Rocuronium; D005045:Etomidate