title: Recognizing hospitalized heart failure as an entity and developing new therapies to improve outcomes: academics', clinicians', industry's, regulators', and payers' perspectives.
abstract: Hospitalized heart failure (HHF) is associated with unacceptably high postdischarge mortality and rehospitalization rates. This heterogeneous group of patients, however, is still treated with standard, homogenous therapies that are not preventing their rapid deterioration. The costs associated with HHF have added demands from society, government, and payers to improve outcomes. With coordinated and committed efforts in the development of new therapies, improvements may be seen in outcomes for patients with HHF. This article summarizes concepts in developing therapies for HHF discussed during a multidisciplinary panel at the Heart Failure Society of America's Annual Scientific Meeting, September 2012.
authors.affiliation: Center for Cardiovascular Innovation, Northwestern University Feinberg School of Medicine, 645 North Michigan Avenue, Chicago, IL 60611, USA. m-gheorghiade@northwestern.edu
authors.forename: Mihai
authors.initials: M
authors.lastname: Gheorghiade
authors.forename: Ami N
authors.initials: AN
authors.lastname: Shah
authors.forename: Muthiah
authors.initials: M
authors.lastname: Vaduganathan
authors.forename: Javed
authors.initials: J
authors.lastname: Butler
authors.forename: Robert O
authors.initials: RO
authors.lastname: Bonow
authors.forename: Giuseppe M C
authors.initials: GM
authors.lastname: Rosano
authors.forename: Scott
authors.initials: S
authors.lastname: Taylor
authors.forename: Stuart
authors.initials: S
authors.lastname: Kupfer
authors.forename: Frank
authors.initials: F
authors.lastname: Misselwitz
authors.forename: Arjun
authors.initials: A
authors.lastname: Sharma
authors.forename: Gregg C
authors.initials: GC
authors.lastname: Fonarow
mesh_terms: D035843:Biomedical Research / Q000458:organization & administration*; D017281:Cost of Illness; D019468:Disease Management; D006333:Heart Failure / Q000191:economics* / Q000628:therapy*; D006760:Hospitalization / Q000191:economics*; D006801:Humans; D012042:Registries