title: An update on saccharide arrays.
abstract: Saccharide arrays are powerful tools to investigate the saccharide-mediated recognition events in highthroughput mode. Many methods have been used to immobilize the saccharides on support surface in the array format. The array-based technologies were widely utilized to analyze the characters of saccharide-binding lectins and antibodies, quantitatively determine saccharide-protein interactions, detect cells and pathogens, identify disease-related antisaccharide antibodies for diagnosis, and fast assess substrate specificities of glycosyltransferases. This review has mainly summarized the fabrication methods of saccharide arrays and their applications in recent years.
authors.affiliation: College of Chemistry, Chongqing Normal University, Chongqing, 401331, China. huangdoctor226@163.com
authors.forename: Gangliang
authors.initials: G
authors.lastname: Huang
authors.forename: Yingxue
authors.initials: Y
authors.lastname: Zhang
authors.forename: Hong
authors.initials: H
authors.lastname: Xu
mesh_terms: D000906:Antibodies / Q000737:chemistry / Q000276:immunology; D004926:Escherichia coli / Q000302:isolation & purification / Q000378:metabolism; D006801:Humans; D037102:Lectins / Q000737:chemistry / Q000378:metabolism; D046228:Microarray Analysis; D053758:Nanoparticles / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry / Q000276:immunology / Q000378:metabolism*; D011485:Protein Binding
chemical_list: D000906:Antibodies; D037102:Lectins; D011134:Polysaccharides