title: Polar body biopsy.
abstract: Polar body biopsy combined with array comparative genomic hybridization allows detection of maternal chromosomal aberrations. Although it has limitations, it can be seen as an alternative to blastomere and trophectoderm biopsy.
authors.affiliation: Department of Gynecologic Endocrinology and Fertility Disorders, Ruprecht-Karls University Heidelberg, Heidelberg, Germany. mmontag@ilabcomm.com
authors.forename: Markus
authors.initials: M
authors.lastname: Montag
authors.forename: Maria
authors.initials: M
authors.lastname: Köster
authors.forename: Thomas
authors.initials: T
authors.lastname: Strowitzki
authors.forename: Bettina
authors.initials: B
authors.lastname: Toth
mesh_terms: D001706:Biopsy / Q000379:methods; D055028:Comparative Genomic Hybridization / Q000379:methods; D020732:Cytogenetic Analysis / Q000379:methods; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence / Q000379:methods; D059705:Polar Bodies / Q000473:pathology*; D011237:Predictive Value of Tests; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*
keywords: PGS; Polar body biopsy; aneuploidy; array-CGH; oocyte