title: Comparative assessment of left ventricular function variables determined via cardiac computed tomography and cardiac magnetic resonance imaging in dogs.
abstract: OBJECTIVE
  To evaluate the accuracy and reproducibility of left ventricular (LV) volumetric and function variables determined via contrast-enhanced cardiac CT and cardiac MRI in healthy dogs.
  
  
  METHODS
  10 healthy Beagles.
  
  
  METHODS
  Cardiac MRI and cardiac CT were performed in anesthetized Beagles; both examinations were conducted within a 2-hour period. Cardiac MRI was performed with a 3.0-T magnet, and contrast-enhanced cardiac CT was performed with a 64-row detector CT machine. Data sets were acquired during apnea with simultaneous ECG gating. Short-axis images were created to determine functional variables via the Simpson method.
  
  
  RESULTS
  Cardiac CT values for mean end-diastolic and end-systolic LV volumes had excellent correlation (r = 0.95) with cardiac MRI measurements, whereas LV stroke volume (r = 0.67) and LV ejection fraction (r = 0.75) had good correlations. The only variable that differed significantly between imaging modalities was end-diastolic LV volume. For each pair of values, Bland-Altman analysis revealed good limits of agreement.
  
  
  CONCLUSIONS
  The 3-D modalities cardiac CT and cardiac MRI were excellent techniques for use in assessing LV functional variables. Similar results were obtained for LV volume and function variables via both techniques. The major disadvantage of these modalities was the need to anesthetize the dogs for the examinations.
authors.affiliation: Small Animal Clinic, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
authors.forename: Anne K
authors.initials: AK
authors.lastname: Sieslack
authors.forename: Peter
authors.initials: P
authors.lastname: Dziallas
authors.forename: Ingo
authors.initials: I
authors.lastname: Nolte
authors.forename: Patrick
authors.initials: P
authors.lastname: Wefstaedt
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000008:administration & dosage / Q000494:pharmacology; D004285:Dogs / Q000502:physiology*; D005260:Female; D007472:Iohexol / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000494:pharmacology; D008279:Magnetic Resonance Imaging / Q000662:veterinary*; D008297:Male; D014057:Tomography, X-Ray Computed / Q000662:veterinary*; D016277:Ventricular Function, Left / Q000502:physiology*
chemical_list: D003287:Contrast Media; C093233:iobitridol; D007472:Iohexol