title: Intrathecal infusion of microglia cells.
abstract: Spinal microglia have been implicated in the pathogenesis of neuropathic pain after peripheral nerve injury concomitant with diseases such as diabetes and cancer. To reveal the etiological roles of microglia in behavioral pain hypersensitivity or neuronal excitability, technical approaches have been used. Here, we describe a technique for intrathecal transfer of cultured microglial cells through a catheter surgically implanted into the spinal subarachnoid space.
authors.affiliation: Kyushu University, Fukuoda, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Masuda
authors.forename: Makoto
authors.initials: M
authors.lastname: Tsuda
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Tozaki-Saitoh
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Inoue
mesh_terms: D000818:Animals; D007278:Injections, Spinal; D008297:Male; D051379:Mice; D017628:Microglia / Q000166:cytology*; D009437:Neuralgia / Q000209:etiology; D059348:Peripheral Nerve Injuries / Q000209:etiology; D013116:Spinal Cord / Q000473:pathology