title: Neuronal beacon.
abstract: The controlled navigation of the axonal growth cone of a neuron toward the dendrite of its synaptic partner neuron is the fundamental process in forming neuronal circuitry. While a number of technologies have been pursued for axonal guidance over the past decades, they are either invasive or not controllable with high spatial and temporal resolution and are often limited by low guidance efficacy. Here, we report a neuronal beacon based on light for highly efficient and controlled guidance of cortical primary neurons.
authors.affiliation: Biophysics and Physiology Laboratory, Department of Physics, The University of Texas at Arlington, Texas 76019, USA.
authors.forename: B
authors.initials: B
authors.lastname: Black
authors.forename: A
authors.initials: A
authors.lastname: Mondal
authors.forename: Y
authors.initials: Y
authors.lastname: Kim
authors.forename: S K
authors.initials: SK
authors.lastname: Mohanty
mesh_terms: D000818:Animals; D001369:Axons / Q000378:metabolism / Q000528:radiation effects; D002540:Cerebral Cortex / Q000166:cytology; D007259:Infrared Rays; D007834:Lasers; D009474:Neurons / Q000166:cytology* / Q000528:radiation effects*; D055096:Optical Devices; D051381:Rats