title: Safe and effective mouse footpad inoculation.
abstract: Footpad injection is an important route of inoculation in mouse models of disease and immunology. Although commonly used to deliver antigens as a means of eliciting an efficacious immunological response, herein, we describe a protocol for inoculating mice via footpad injection using a hands-free method to deliver infectious material. These procedures allow for efficient delivery of infectious agents in a manner that is safe for both the researcher and animal.
authors.affiliation: Department of Genetics, The University of North Carolina, Chapel Hill, NC, USA.
authors.forename: Kristin M
authors.initials: KM
authors.lastname: Long
authors.forename: Mark
authors.initials: M
authors.lastname: Heise
mesh_terms: D000818:Animals; D000941:Antigens / Q000008:administration & dosage*; D004195:Disease Models, Animal; D007267:Injections / Q000379:methods*; D051379:Mice; D014611:Vaccination / Q000379:methods*
chemical_list: D000941:Antigens