title: Self-reported low physical function is associated with diabetes mellitus and insulin resistance in HIV-positive and HIV-negative men.
abstract: OBJECTIVE
  To investigate the association between self-reported physical function (as a surrogate for physical activity) and diabetes mellitus (DM) and insulin resistance (IR) among HIV-positive and -negative men.
  
  
  METHODS
  A total of 384 HIV-negative and 274 HIV-positive men from the Pitt Men's Study contributed data. DM was defined by fasting serum glucose levels. IR was calculated using the homeostasis model assessment. The Physical Functioning 10 Scale from the Short Form-36 Health Survey measured physical function. Multivariate logistic regression assessed the independent association between physical function and DM and IR.
  
  
  RESULTS
  Physical function, older age and Black race were associated with DM in multivariate analyses. Physical function/HIV interaction, older age, higher body mass index, HIV infection and Black race were associated with IR in multivariate analyses.
  
  
  CONCLUSIONS
  Self-reported low physical function is associated with DM and IR in HIV-negative and -positive men.
authors.affiliation: Graduate School of Public Health, Department of Epidemiology, University of Pittsburgh, Fifth Avenue and Desoto Street, Pittsburgh, PA 15261, USA.
authors.forename: Allison
authors.initials: A
authors.lastname: Longenberger
authors.forename: Jeong Youn
authors.initials: JY
authors.lastname: Lim
authors.forename: Trevor
authors.initials: T
authors.lastname: Orchard
authors.forename: Maria Mori
authors.initials: MM
authors.lastname: Brooks
authors.forename: Jennifer
authors.initials: J
authors.lastname: Brach
authors.forename: Kristen
authors.initials: K
authors.lastname: Mertz
authors.forename: Lawrence A
authors.initials: LA
authors.lastname: Kingsley
keywords: HIV-positive; diabetes mellitus; insulin resistance; physical function