title: Synthesis of a C1-C11 fragment of Zincophorin using planar chiral, neutral π-allyl iron complexes.
abstract: A key step in the synthesis of a C1-C11 fragment of the ionophore antibiotic Zincophorin involves the addition of an α-alkoxyalkylcopper(I) reagent to a planar chiral, neutral π-allyl iron complex. The key allylic alkylation reaction is highly regio- and stereoselective with addition taking place at the γ-position anti to the metal centre.
authors.affiliation: School of Chemistry, University of Leeds, Leeds LS2 9JT, UK. j.p.cooksey@leeds.ac.uk
authors.forename: John P
authors.initials: JP
authors.lastname: Cooksey
mesh_terms: D000478:Alkylation; D056831:Coordination Complexes / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D015394:Molecular Structure; D011422:Propionates / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D056831:Coordination Complexes; D011422:Propionates; C043279:zincophorin; D007501:Iron