title: Metabolism: gut microbiota modulates diurnal secretion of glucocorticoids.
abstract: A new study has identified the sophisticated communication between the gut microbiota and intestinal epithelial cells that controls diurnal variations in the secretion of corticosteroids in mice. The absence of gut bacteria disrupts this communication and contributes to hypertriglyceridaemia, hyperglycaemia and insulin resistance.
authors.forename: M Mahmood
authors.initials: MM
authors.lastname: Hussain
mesh_terms: D000305:Adrenal Cortex Hormones / Q000378:metabolism; D000818:Animals; D004847:Epithelial Cells / Q000378:metabolism*; D041981:Gastrointestinal Tract / Q000378:metabolism* / Q000382:microbiology*; D005938:Glucocorticoids / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000166:cytology*; D051379:Mice
chemical_list: D000305:Adrenal Cortex Hormones; D005938:Glucocorticoids