title: Metastatic Malignant Melanoma to Urinary Bladder: A Potential Pitfall for High-Grade Urothelial Carcinoma.
abstract: We present a case of a 61-year-old female presenting with a bladder tumor that occurred 7 years after her previous diagnosis of Clark's level III mid-back melanoma. The bladder tumor was submitted to histopathology without accompanying clinical history, and an initial diagnosis of high-grade urothelial carcinoma was rendered based on epithelioid and sarcomatoid appearing pleomorphic histopathology. We present this case to highlight the diagnostic challenge presented by the rare occurrence of metastatic melanoma to the urinary bladder and the potential pitfall of this lesion being diagnosed as high-grade urothelial carcinoma in the presence of limited clinical history.
authors.affiliation: Mount Sinai School of Medicine, New York, NY, USA arvind_rishi@yahoo.com.
authors.forename: Arvind
authors.initials: A
authors.lastname: Rishi
authors.affiliation: Mount Sinai School of Medicine, New York, NY, USA.
authors.forename: Todd A
authors.initials: TA
authors.lastname: Anderson
authors.affiliation: Mount Sinai School of Medicine, New York, NY, USA.
authors.forename: Alexander M
authors.initials: AM
authors.lastname: Kirschenbaum
authors.affiliation: Mount Sinai School of Medicine, New York, NY, USA.
authors.forename: Pamela D
authors.initials: PD
authors.lastname: Unger
mesh_terms: D002295:Carcinoma, Transitional Cell / Q000175:diagnosis; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008545:Melanoma / Q000556:secondary*; D008875:Middle Aged; D060787:Neoplasm Grading; D012878:Skin Neoplasms / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000556:secondary*
keywords: bladder; malignant; melanoma; metastasis; neoplasm