title: Acquired oculomotor nerve paresis with cyclic spasms in a young woman, a rare subtype of neuromyotonia.
abstract: BACKGROUND
  To report an unusual case of cyclic oculomotor nerve paresis and spasms, which developed 5 years following brain radiotherapy for cerebellar medulloblastoma.
  
  
  METHODS
  Observational case report.
  
  
  RESULTS
  The cyclic oculomotor nerve paresis and spasms resolved in our patient when treated with carbamazepine. However, because of severe photophobia and tearing, carbamazepine had to be discontinued leading to reappearance of the eye movement disorder.
  
  
  CONCLUSIONS
  Cyclic oculomotor nerve paresis and spasms appear to be a delayed effect of radiotherapy and respond to carbamazepine therapy. It may be a rare form of ocular neuromyotonia.
authors.affiliation: Department of Neurology, Tel Aviv University, Tel Aviv, Israel. avigadoth@gmail.com
authors.forename: Avi
authors.initials: A
authors.lastname: Gadoth
authors.forename: Svetlana
authors.initials: S
authors.lastname: Kipervasser
authors.forename: Amos D
authors.initials: AD
authors.lastname: Korczyn
authors.forename: Miri Y
authors.initials: MY
authors.lastname: Neufeld
authors.forename: Anat
authors.initials: A
authors.lastname: Kesler
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D002220:Carbamazepine / Q000627:therapeutic use; D002528:Cerebellar Neoplasms / Q000532:radiotherapy; D005260:Female; D006801:Humans; D020386:Isaacs Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008527:Medulloblastoma / Q000532:radiotherapy; D015840:Oculomotor Nerve Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine