title: Effect of physical restraint on glucose tolerance in cynomolgus monkeys.
abstract: BACKGROUND
  Physiologic stress has been demonstrated to impair glucose tolerance.
  
  
  METHODS
  Glucose tolerance tests were performed using six cynomolgus monkeys.
  
  
  RESULTS
  Chair-restrained subjects elicited higher elevations of plasma glucose and cortisol compared with squeezing device-restrained subjects.
  
  
  CONCLUSIONS
  The responses to a glucose challenge are altered by different restraint procedures.
authors.affiliation: Biological Research Laboratories, Daiichi-Sankyo Co, Ltd, Tokyo, Japan. shirasaki.yasufumi.n7@daiichisankyo.co.jp
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Shirasaki
authors.forename: Naoya
authors.initials: N
authors.lastname: Yoshioka
authors.forename: Kanpei
authors.initials: K
authors.lastname: Kanazawa
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Maekawa
authors.forename: Tadahiro
authors.initials: T
authors.lastname: Horikawa
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Hayashi
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D005260:Female; D005951:Glucose Tolerance Test; D008252:Macaca fascicularis / Q000502:physiology*; D012149:Restraint, Physical / Q000379:methods*; D013312:Stress, Physiological
chemical_list: D001786:Blood Glucose