title: Genome Sequences of a Novel HIV-1 Circulating Recombinant Form (CRF59_01B) Identified among MSM in China.
abstract: We report here a novel HIV-1 circulating recombinant form (CRF59_01B), isolated from three epidemiologically unlinked men who have sex with men (MSM) in China. CRF59_01B was composed of subtype CRF01_AE and B, with four identical recombinant breakpoints observed in the pol, env genes and between the 3' tat (or rev) and vpu genes. The emergence of CRF59_01B suggests the increasing significance of homosexual transmission in China's HIV epidemic and may indicate an active transmission network of HIV infections among MSM population in China. Further studies of the molecular epidemiology of HIV-1 epidemic among MSM population in China are necessary to gain a fuller understanding of the transmission network and potential public health impact of HIV -1 among MSM population in this region.
authors.affiliation: Wuhan Institute of Virology, University of Chinese Academy of Sciences, HIV Molecular Epidemiology and Virology Research Group, The State Key Laboratory of Virology, Xiaohongshan 44, Wuhan, Hubei, Wuhan, Hubei , China, 430071, China CDC, Division of Research on Virology and Immunology, National Center for AIDS/STD Control and Prevention, 155 Changbai Road, Changping district, Beijing, Bejing, China, 102206 ; xingguanglee@hotmail.com.
authors.forename: Xingguang
authors.initials: X
authors.lastname: Li
authors.forename: Chuanyi
authors.initials: C
authors.lastname: Ning
authors.forename: Xiang
authors.initials: X
authors.lastname: He
authors.forename: Yao
authors.initials: Y
authors.lastname: Yang
authors.forename: Hui
authors.initials: H
authors.lastname: Xing
authors.forename: Kunxue
authors.initials: K
authors.lastname: Hong
authors.forename: Rongge
authors.initials: R
authors.lastname: Yang
authors.forename: Yiming
authors.initials: Y
authors.lastname: Shao