title: Modelling interventions during a dengue outbreak.
abstract: We present a stochastic dynamical model for the transmission of dengue that considers the co-evolution of the spatial dynamics of the vectors (Aedes aegypti) and hosts (human population), allowing the simulation of control strategies adapted to the actual evolution of an epidemic outbreak. We observed that imposing restrictions on the movement of infected humans is not a highly effective strategy. In contrast, isolating infected individuals with high levels of compliance by the human population is efficient even when implemented with delays during an ongoing outbreak. We also studied insecticide-spraying strategies assuming different (hypothetical) efficiencies. We observed that highly efficient fumigation strategies seem to be effective during an outbreak. Nevertheless, taking into account the controversial results on the use of spraying as a single control strategy, we suggest that carrying out combined strategies of fumigation and isolation during an epidemic outbreak should account for a suitable strategy for the attenuation of epidemic outbreaks.
authors.affiliation: Departamento de Física, FCEN-UBA and IFIBA-CONICET, Pabellón I, Ciudad Universitaria, Buenos Aires, Argentina.
authors.forename: D H
authors.initials: DH
authors.lastname: Barmak
authors.affiliation: Departamento de Física, FCEN-UBA and IFIBA-CONICET, Pabellón I, Ciudad Universitaria, Buenos Aires, Argentina.
authors.forename: C O
authors.initials: CO
authors.lastname: Dorso
authors.affiliation: Departamento de Física, FCEN-UBA and IFIBA-CONICET, Pabellón I, Ciudad Universitaria, Buenos Aires, Argentina.
authors.forename: M
authors.initials: M
authors.lastname: Otero
authors.affiliation: Departamento de Física, FCEN-UBA and IFIBA-CONICET, Pabellón I, Ciudad Universitaria, Buenos Aires, Argentina.
authors.forename: H G
authors.initials: HG
authors.lastname: Solari
mesh_terms: D000330:Aedes; D000818:Animals; D003715:Dengue / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D004196:Disease Outbreaks / Q000517:prevention & control*; D006801:Humans; D007303:Insect Vectors; D007306:Insecticides; D008954:Models, Biological; D008962:Models, Theoretical; D010356:Patient Isolation
chemical_list: D007306:Insecticides