title: Magic bullets from llamas.
abstract: Monoclonal antibodies are effective therapies for many disorders, but their nature and use continues to evolve as technologies emerge to improve their drug-like qualities. In this issue of Structure, Schmitz and colleagues report on structural and biophysical characterizations of single-domain "nanobodies" from llamas that target the epidermal growth factor receptor by both old and new mechanisms.
authors.affiliation: Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA. dleahy@jhmi.edu
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Leahy
mesh_terms: D066246:ErbB Receptors / Q000737:chemistry*; D006801:Humans; D061905:Single-Domain Antibodies / Q000737:chemistry*
chemical_list: D061905:Single-Domain Antibodies; C512478:EGFR protein, human; D066246:ErbB Receptors