title: The key role of psychosocial risk on therapeutic outcome in obese children and adolescents. Results from a longitudinal multicenter study.
abstract: OBJECTIVE
  Childhood obesity is high on the global public health agenda. Although risk factors are well known, the influence of social risk on the therapeutic outcome of lifestyle intervention is poorly examined. This study aims to investigate the influence of migration background, low education, and parental unemployment.
  
  
  METHODS
  62,147 patients participated in multidimensional lifestyle intervention programs in 179 pediatric obesity centers. Data were collected using standardized software for longitudinal multicenter documentation. 12,305 (19.8%) attended care for 6-24 months, undergoing an intensive therapy period and subsequent follow-ups for up to 3 years. A cumulative social risk score was calculated based on different risk indicators.
  
  
  RESULTS
  Migration background, low education, and parental employment significantly influenced the outcome of lifestyle intervention. The observed BMI-SDS reduction was significantly higher in the subgroup with low social risks factors (Δ BMI-SDS -0.19) compared to those presenting moderate (Δ BMI-SDS -0.14) and high social risk (Δ BMI-SDS -0.11).
  
  
  CONCLUSIONS
  Our data underline the effect of children's social setting on the outcome of multidimensional lifestyle intervention. The presence of a high social risk burden is a negative predictor for successful weight loss. Specific therapeutic programs need to be developed for disadvantaged children and adolescents.
authors.affiliation: Department of Pediatrics and Pediatric Neurology, University Medical Center Göttingen, Göttingen, Germany.
authors.forename: Markus
authors.initials: M
authors.lastname: Röbl
authors.forename: Martin
authors.initials: M
authors.lastname: de Souza
authors.forename: Ralf
authors.initials: R
authors.lastname: Schiel
authors.forename: Ines
authors.initials: I
authors.lastname: Gellhaus
authors.forename: Karl
authors.initials: K
authors.lastname: Zwiauer
authors.forename: Reinhard W
authors.initials: RW
authors.lastname: Holl
authors.forename: Susanna
authors.initials: S
authors.lastname: Wiegand
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D002648:Child; D004522:Educational Status; D054242:Emigrants and Immigrants; D004641:Emigration and Immigration; D004651:Employment; D005260:Female; D005500:Follow-Up Studies; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D008137:Longitudinal Studies; D008297:Male; D010290:Parents; D063766:Pediatric Obesity / Q000523:psychology / Q000628:therapy*; D012307:Risk Factors; D012931:Social Environment; D016896:Treatment Outcome; D015431:Weight Loss; D061217:Weight Reduction Programs