title: Sleep quality assessment using polysomnography in children on regular hemodialysis.
abstract: Studies examining sleep patterns in children on hemodialysis (HD) are lacking. This cross-sectional, control-matched group study was performed to assess the sleep quality in children on HD. The assessment was made using a subjective sleep assessment and sleep questionnaire and objective analysis was made using full night polysomnography. A total of 25 children with end-stage renal disease (ESRD) on HD were compared with 15 age- and sex-matched controls. The average age of the cases was 14 ± 4 years, 52% were males and the mean body mass index was 20 ± 3.8 kg/m². The average duration on dialysis was 2.6 ± 2 years. Analysis of subjective data revealed markedly affected sleep quality in HD patients, as evidenced by excessive day time sleepiness (P <0.005), night awakening (P <0.005), difficult morning arousal (P <0.005) and limb pains (P <0.005). Objective analysis showed differences in sleep architecture, less slow wave sleep in HD children, similar rapid eye movement and non-rapid eye movement, more sleep disordered breathing (P <0.0001) and more periodic limb movement disorders (P <0.0001). Our study suggests that children on regular HD have markedly affected objective as well as subjective quality of sleep.
authors.affiliation: Pediatric Department, Mansoura University Children's Hospital, Egypt.
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: El-Refaey
authors.forename: Riad M
authors.initials: RM
authors.lastname: Elsayed
authors.forename: Amr
authors.initials: A
authors.lastname: Sarhan
authors.forename: Ashraf
authors.initials: A
authors.lastname: Bakr
authors.forename: Ayman
authors.initials: A
authors.lastname: Hammad
authors.forename: Atef
authors.initials: A
authors.lastname: Elmougy
authors.forename: Ahmed Y
authors.initials: AY
authors.lastname: Aboelyazeed
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D017286:Polysomnography; D011788:Quality of Life; D006435:Renal Dialysis; D012893:Sleep Wake Disorders