title: Do psychiatric disorders continue during pregnancy in women with hyperemesis gravidarum: a prospective study.
abstract: OBJECTIVE
  We aimed to determine Axis I psychiatric disorders in women with hyperemesis gravidarum (HG) and to follow up the course of psychiatric disorder and its association with nausea and vomiting (NV) during pregnancy.
  
  
  METHODS
  The study sample was composed of 47 patients with HG. Psychiatric interviews were conducted using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (SCID-I). Other psychiatric interviews were performed in the second and third trimesters. On each visit, the subjects completed the Beck Depression Inventory and the Beck Anxiety Inventory.
  
  
  RESULTS
  The prevalence of any anxiety disorder was 25.5%, and the prevalence of any mood disorder was 14.9% in women with HG in the first trimester. Psychiatric disorders continued throughout the pregnancy in two thirds of the women who had HG and a psychiatric diagnosis. Any SCID diagnosis in the first trimester was higher in women whose NV had partially resolved than in women whose NV had fully resolved (P<.05).
  
  
  CONCLUSIONS
  The present studies suggest that psychiatric disorders may play a significant role in the etiology of HG. Our findings presented a potential connection between HG and anxiety disorders and major depressive disorder. Additionally, the NV symptoms in women with HG and a psychiatric disorder may persist during pregnancy.
authors.affiliation: Department of Psychiatry, Faculty of Medicine, Selcuk University, Konya 42131, Turkey. Electronic address: bilgeannagur@yahoo.com.
authors.forename: Bilge Burçak
authors.initials: BB
authors.lastname: Annagür
authors.forename: Aybike
authors.initials: A
authors.lastname: Tazegül
authors.forename: Sule
authors.initials: S
authors.lastname: Gündüz
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000150:complications / Q000453:epidemiology; D005260:Female; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000453:epidemiology / Q000209:etiology / Q000523:psychology*; D007406:Interview, Psychological; D001523:Mental Disorders / Q000150:complications* / Q000453:epidemiology; D019964:Mood Disorders / Q000150:complications / Q000453:epidemiology; D011247:Pregnancy; D015995:Prevalence; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D055815:Young Adult
keywords: Anxiety; Depression; Hyperemesis gravidarum; Psychiatric etiology