title: Hemostasis in acute liver and kidney failure: nothing is as it seems.
abstract: Very little is known about the behavior of the hemostatic system in patients with acute kidney injury (AKI) associated with acute liver failure (ALF). Agarwal and colleagues show that patients who suffer from both ALF and AKI exhibit a higher degree of hemostasis impairment than those with normal renal function. Both anticoagulant and procoagulant factors were impaired. The development of AKI appears to displace the hemostatic equilibrium toward a more prothrombotic pattern.
authors.affiliation: Intensive Care Unit, Department of Anaesthesiology and Intensive Care, University Hospital of Modena, Modena, Italy. girardis.massimo@unimo.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Girardis
authors.forename: Marco
authors.initials: M
authors.lastname: Marietta
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood* / Q000209:etiology*; D005260:Female; D006487:Hemostasis; D006801:Humans; D017114:Liver Failure, Acute / Q000097:blood* / Q000150:complications*; D008297:Male