title: Neoadjuvant chemotherapy and salvage surgery for an aldosterone-producing adrenal carcinoma with inferior vena cava thrombus: case report and literature review.
abstract: Inferior vena cava (IVC) thrombus is a rare presentation of adrenal carcinoma. Hyperladosteronism is rarely associated with it. We report a case of an aldosterone-producing left adrenal carcinoma with IVC thrombus and invasion of multiple organs, treated with neoadjuvant chemotherapy and salvage surgery. The patient is alive and asymptomatic after 46 months. Surgical aspects and therapeutic options are discussed and compared with the current medical literature. This is believed to be the first report of multiple organ resection combined with IVC thrombus removal for a functioning adrenal carcinoma.
authors.affiliation: Department of Surgical Oncology, DF Cancer Institute, Brazil. carancastro@bol.com.br
authors.forename: Carlos
authors.initials: C
authors.lastname: Rangel
authors.forename: Gabrielle
authors.initials: G
authors.lastname: Scattolin
authors.forename: Sergio Renato
authors.initials: SR
authors.lastname: Pais-Costa
authors.forename: Eduardo
authors.initials: E
authors.lastname: Vieira
authors.forename: Eduardo
authors.initials: E
authors.lastname: Gaio
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D000315:Adrenalectomy; D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000209:etiology*; D020360:Neoadjuvant Therapy; D016879:Salvage Therapy; D014682:Vena Cava, Inferior / Q000601:surgery*; D020246:Venous Thrombosis / Q000209:etiology* / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents