title: [Effect of anti-osteoporotic agents on cortical microstructure].
abstract: The incidence of non-vertebral fracture increases in old age, and the deterioration of cortical micro-structure is considered to be one of important reason to cause non-vertebral fracture. In this chapter, the age-related change of cortical microstructure, relationship with bone strength are discussed as well as the effect of anti-osteoporotic drugs on cortical bone ; bisphosphonate, teriparatide, active vitamin D3, and denosumab.
authors.affiliation: Medical Work-Life-Balance Center, Nagasaki University Hospital, Japan.
authors.forename: Masako
authors.initials: M
authors.lastname: Ito
mesh_terms: D000375:Aging; D015519:Bone Density / Q000187:drug effects*; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D001842:Bone and Bones / Q000187:drug effects* / Q000648:ultrastructure; D006801:Humans; D058866:Osteoporotic Fractures / Q000188:drug therapy*
chemical_list: D050071:Bone Density Conservation Agents