title: [Dupuytren's contracture associated with silicone wear reaction in late failure of lunate bone spacer prosthesis].
abstract: The pathophysiological mechanisms of palmar fibromatosis (Dupuytren's contracture) are still not yet fully understood. In the vast majority of cases, however, reactive changes and reparative processes of tendon tissue can easily be ruled out by clinical and histopathological investigations. This article presents the case of a 62-year-old male patient suffering from palmar fibromatosis associated with a failed silicon spacer of the lunate bone 30 years after index surgery. Although silicon wear particles were observed in distal locations, proximal tendon tissues showed changes consistent with a degenerative palmar fibromatosis in the absence of a pathological wear reaction. The findings are discussed in the light of the current literature on Dupuytren's contracture.
authors.affiliation: Klinik und Poliklinik für Orthopädie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland. c.v.domarus@uke.uni-hamburg.de
authors.forename: C
authors.initials: C
authors.lastname: von Domarus
authors.forename: F T
authors.initials: FT
authors.lastname: Beil
authors.forename: S
authors.initials: S
authors.lastname: Seitz
authors.forename: W
authors.initials: W
authors.lastname: Rüther
authors.forename: J
authors.initials: J
authors.lastname: Zustin
mesh_terms: D001672:Biocompatible Materials / Q000009:adverse effects*; D004387:Dupuytren Contracture / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007595:Joint Prosthesis / Q000009:adverse effects*; D012667:Lunate Bone / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012828:Silicones / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; D012828:Silicones