title: p53: the TRiC is knowing when to fold 'em.
abstract: In this issue, Trinidad et al. (2013) show that CCT/TRiC is a chaperone required for p53 folding, thus providing another layer of regulation of p53 function, with implications for cancer therapeutics targeting the p53 pathway.
authors.affiliation: Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.
authors.forename: Jessica
authors.initials: J
authors.lastname: Monteith
authors.forename: Steven B
authors.initials: SB
authors.lastname: McMahon
mesh_terms: D056385:Group II Chaperonins / Q000378:metabolism*; D006801:Humans; D017510:Protein Folding; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*
chemical_list: C495901:TP53 protein, human; D016159:Tumor Suppressor Protein p53; D056385:Group II Chaperonins