title: Fibro-osseous lesions of the oral and maxillo-facial region: Retrospective analysis for 20 years.
abstract: BACKGROUND
  Fibro-osseous lesions (FOLs) are one of the commonest entities reported in the head and neck region. However, studies on these groups of lesions on Indian population were not carried out before. So this motivated us to analyze the clinico-pathologic correlation of fibro-osseous lesions reported at our hospital.
  
  
  METHODS
  A retrospective review was made of all the lesions surgically treated in our hospital. A total of 6,175 biopsies were performed during the study period. All the cases which were histopathologically diagnosed as FOLs were included in the study. The demographic data, radiographic features, and histopathologic findings were analyzed and compared with similar studies on other races.
  
  
  CONCLUSIONS
  We could find 80 cases diagnosed as fibro-osseous lesions and information about them was documented. The most common FOL reported in the region was cemento-ossifying fibroma (COF) (75%) than fibrous dysplasia (FD) (25%). These were commonly occurring in 2(nd) decade without any sex or site predilection. However, COF was showing a slight female predominance and FD with a definite male predominance. COF was commonly seen in mandible (posterior region) whereas FD mainly confined to the maxilla (as a whole bone). Radiographically, most of COF showed well-defined mixed opaque and lucent areas whereas FD showed diffuse borders. Cortical plate expansion and resorption of associated teeth was a frequent finding in COF when compared with FD. Histopathologically, stroma was fibrocellular in many cases of COF, whereas most FDs showed fibrous stroma, interspersed with mainly woven bone.
authors.affiliation: Department of Oral Pathology, Yenepoya Dental College, Yenepoya University, Mangalore, Karnataka, India.
authors.forename: Sudeendra
authors.initials: S
authors.lastname: Prabhu
authors.forename: S
authors.initials: S
authors.lastname: Sharanya
authors.forename: Pooja M
authors.initials: PM
authors.lastname: Naik
authors.forename: Ashritha
authors.initials: A
authors.lastname: Reddy
authors.forename: Vatsala
authors.initials: V
authors.lastname: Patil
authors.forename: Sameer
authors.initials: S
authors.lastname: Pandey
authors.forename: Alok
authors.initials: A
authors.lastname: Mishra
authors.forename: K
authors.initials: K
authors.lastname: Rekha
keywords: Cemento-ossifying fibroma; fibro-osseous lesions; fibrous dysplasia