title: Complications after laparoscopic and open subtotal colectomy for inflammatory colitis: a case-matched comparison.
abstract: OBJECTIVE
  The aim of this study was to compare the early postoperative outcome of patients undergoing laparoscopic subtotal colectomy with those undergoing open subtotal colectomy for colitis refractory to medical treatment.
  
  
  METHODS
  A retrospective observational study was carried out of patients who underwent subtotal colectomy for refractory colitis, at a single centre, between 2006 and 2012. Patients were matched for age, gender, American Society of Anesthesiology (ASA) grade, urgency of operation and immunosuppressant/modulator treatment. The primary outcome measure was the number of postoperative complications, classified using the Clavien-Dindo scale. Secondary end-points included procedure duration, laparoscopic conversion rates, blood loss, 30-day readmission rates and length of hospital stay.
  
  
  RESULTS
  Ninety-six patients were included, 39 of whom had laparoscopic surgery. Thirty-two of these were matched to similar patients who underwent an open procedure. The overall duration of the procedure was longer for laparoscopic surgery than for open surgery (median: 240 vs 150 min, P < 0.005) but estimated blood loss was less (median: 75 vs 400 ml, P < 0.005). In the laparoscopic group, 23 patients experienced 27 complications, and in the open surgery group, 23 patients experienced 30 complications. Most complications were minor (Grade I/II), and the distribution of complications, by grade, was similar between the two groups. There was no statistically significant difference in 30-day readmission rates between the laparoscopic and open groups (five readmissions vs eight readmissions, P = 0.536). Length of hospital stay was 4 days shorter for laparoscopic surgery, but this difference was not statistically significant (median: 7 vs 11 days, P = 0.159).
  
  
  CONCLUSIONS
  In patients requiring colectomy for acute severe colitis, laparoscopic surgery reduced blood loss but increased operating time and was not associated with a reduction in early postoperative complications, length of hospital stay or readmission rates.
authors.affiliation: Department of Surgery, Aberdeen Royal Infirmary, Aberdeen, UK.
authors.forename: C N
authors.initials: CN
authors.lastname: Parnaby
authors.forename: G
authors.initials: G
authors.lastname: Ramsay
authors.forename: C S
authors.initials: CS
authors.lastname: Macleod
authors.forename: N R
authors.initials: NR
authors.lastname: Hope
authors.forename: J O
authors.initials: JO
authors.lastname: Jansen
authors.forename: T K
authors.initials: TK
authors.lastname: McAdam
mesh_terms: D000208:Acute Disease; D000328:Adult; D016063:Blood Loss, Surgical; D003082:Colectomy / Q000009:adverse effects* / Q000379:methods*; D003092:Colitis / Q000209:etiology / Q000601:surgery*; D005260:Female; D006801:Humans; D007081:Ileostomy / Q000009:adverse effects; D015212:Inflammatory Bowel Diseases / Q000150:complications / Q000601:surgery*; D010535:Laparoscopy / Q000009:adverse effects*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D010359:Patient Readmission; D012189:Retrospective Studies
keywords: Inflammatory colitis; laparoscopy; subtotal colectomy