title: Characteristics of extremely low-birth-weight infant survivors with unimpaired outcomes at 30 months of age.
abstract: OBJECTIVE
  To evaluate characteristics of unimpaired outcome in extremely low-birth-weight (ELBW) survivors.
  
  
  METHODS
  ELBW infants (n=714) with 30 months' assessments were analyzed. Logistic regression was used to develop a model for the binary outcome of unimpaired versus impaired outcome.
  
  
  RESULTS
  Thirty-three percent of infants had an unimpaired outcome. Seventeen percent of ELBW survivors had a Bayley II Mental Developmental Index score of ≥ 101 and 2% had a score of ≥ 116. Female gender, use of antenatal steroids (ANS), maternal education ≥ high school and the absence of major neonatal morbidities were independent predictors of unimpaired outcome. The likelihood of an unimpaired outcome in the presence of major neonatal morbidities was higher in infants exposed to ANS.
  
  
  CONCLUSIONS
  The majority of unimpaired ELBW survivors had cognitive scores shifted toward the lower end of the normal distribution. Exposure to ANS was associated with higher likelihood of an unimpaired outcome in infants with major neonatal morbidities.
authors.affiliation: Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
authors.forename: P
authors.initials: P
authors.lastname: Kumar
authors.forename: S
authors.initials: S
authors.lastname: Shankaran
authors.forename: N
authors.initials: N
authors.lastname: Ambalavanan
authors.forename: D E
authors.initials: DE
authors.lastname: Kendrick
authors.forename: A
authors.initials: A
authors.lastname: Pappas
authors.forename: B R
authors.initials: BR
authors.lastname: Vohr
authors.forename: B B
authors.initials: BB
authors.lastname: Poindexter
authors.forename: A
authors.initials: A
authors.lastname: Das
authors.forename: R D
authors.initials: RD
authors.lastname: Higgins
mesh_terms: D002547:Cerebral Palsy / Q000453:epidemiology; D002657:Child Development; D003072:Cognition Disorders / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D052577:Infant, Extremely Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000453:epidemiology; D016015:Logistic Models; D008297:Male