title: Rapid defervescence after doxycycline treatment of macrolide-resistant Mycoplasma pneumoniae-associated community-acquired pneumonia in children.
abstract: We did a retrospective review of children with Mycoplasma pneumoniae infection hospitalized from March 2010 to March 2013. Mycoplasma-resistant M. pneumoniae constituted 70% of the total M. pneumoniae-associated community-acquired pneumonia. Doxycycline was significantly more effective than macrolide for treatment of Mycoplasma-resistant M. pneumoniae-associated community-acquired pneumonia in terms of achievement of rapid defervescence within 24 hours.
authors.affiliation: From the Departments of *Clinical Pathology and †Paediatrics and Adolescent Medicine, Tuen Mun Hospital, Tuen Mun, Hong Kong.
authors.forename: David Christopher
authors.initials: DC
authors.lastname: Lung
authors.forename: Eric Kam Tong
authors.initials: EK
authors.lastname: Yip
authors.forename: David Shu Yan
authors.initials: DS
authors.lastname: Lam
authors.forename: Tak Lun
authors.initials: TL
authors.lastname: Que
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology*; D004318:Doxycycline / Q000627:therapeutic use*; D024881:Drug Resistance, Bacterial; D005260:Female; D005334:Fever / Q000382:microbiology; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D018942:Macrolides / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D009177:Mycoplasma pneumoniae / Q000187:drug effects; D011019:Pneumonia, Mycoplasma / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology*; D012189:Retrospective Studies
chemical_list: D000900:Anti-Bacterial Agents; D018942:Macrolides; D004318:Doxycycline