title: [Value of three risk-stratification criteria in Chinese patients with gastrointestinal stromal tumors].
abstract: OBJECTIVE
  To evaluate the application value of three risk-stratification criteria in domestic GIST risk assessment.
  
  
  METHODS
  The clinical data of 144 patients with GIST who were admitted to our hospital from January 2008 to December 2010 were analyzed retrospectively. 144 cases of GISTs were evaluated for their biologic potential by the risk-stratification criteria of Fletcher, NIH2008, and among those, 119 cases of GISTs were evaluated by the risk-stratification criteria of Miettinen. Fletcher and Miettinen criteria were compared by Kaplan-Meier survival analysis. The Logistic regression model was established to analyze the comparison of Miettinen and NIH2008 criteria.
  
  
  RESULTS
  (1) According to Fletcher criteria in the intermediate risk GISTs, the recurrence-free survival (RFS) of non gastric(small intestinal, rectal and so on) GISTs and gastric GISTs were statistically different (P=0.001). According to Miettinen criteria, in the risk subgroup of GISTs, the recurrence-free survival of different location of GISTs had no statistical difference(P>0.05); (2)Logistic regression model judgment rate: Miettinen criteria (89.4)>NIH2008 criteria (85.2).
  
  
  CONCLUSIONS
  Fletcher criteria is simple and easy to use, but may misjudge the prognosis of the GIST in different part; Miettinen criteria may be a potential supplementary way of NIH2008 criteria in domestic GIST risk assessment.
authors.affiliation: Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. 7543686@qq.com
authors.forename: Tao
authors.initials: T
authors.lastname: Chen
authors.forename: Hao
authors.initials: H
authors.lastname: Liu
authors.forename: Yanfeng
authors.initials: Y
authors.lastname: Hu
authors.forename: Jiang
authors.initials: J
authors.lastname: Yu
authors.forename: Tingyu
authors.initials: T
authors.lastname: Mou
authors.forename: Guoxin
authors.initials: G
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000401:mortality / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology; D015996:Survival Rate; D055815:Young Adult