title: cis-[Pt(II) (1R,2R-DACH)(3-acetoxy-1,1-cyclobutanedicarboxylato)], a water-soluble, oxalate-free and stable analogue of oxaliplatin: synthesis, characterization, and biological evaluations.
authors.affiliation: State Key Lab for Platinum Group Metals, Kunming Institute of Precious Metals, 650106 Yunnan, China.
authors.forename: Weiping
authors.initials: W
authors.lastname: Liu
authors.forename: Qingsong
authors.initials: Q
authors.lastname: Ye
authors.forename: Jing
authors.initials: J
authors.lastname: Jiang
authors.forename: Liguang
authors.initials: L
authors.lastname: Lou
authors.forename: Yongping
authors.initials: Y
authors.lastname: Xu
authors.forename: Chengying
authors.initials: C
authors.lastname: Xie
authors.forename: Mingjin
authors.initials: M
authors.lastname: Xie
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000627:therapeutic use / Q000633:toxicity; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D056831:Coordination Complexes / Q000138:chemical synthesis* / Q000627:therapeutic use / Q000633:toxicity; D018360:Crystallography, X-Ray; D003514:Cyclohexylamines / Q000737:chemistry*; D019073:HT29 Cells; D006801:Humans; D007536:Isomerism; D061986:MCF-7 Cells; D008968:Molecular Conformation; D009369:Neoplasms / Q000188:drug therapy; D009944:Organoplatinum Compounds / Q000737:chemistry* / Q000627:therapeutic use / Q000633:toxicity; D000077150:Oxaliplatin; D010984:Platinum / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: C586996:(Pt(II)(DACH)(3-acetoxy-1,1-cyclobutanedicarboxylato)); D000970:Antineoplastic Agents; D056831:Coordination Complexes; D003514:Cyclohexylamines; D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; D014867:Water; D010984:Platinum; C030435:1,2-cyclohexanediamine
keywords: antitumor agents; biological activity; oxaliplatin; platinum; synthesis