title: Tumors of central and peripheral nervous system associated with inherited genetic syndromes.
abstract: There are several genetic syndromes that predispose to the development of tumors of the nervous system. In the present study, we provide a review of the tumors that are associated with neurofibromatosis type 1, neurofibromatosis type 2, tuberous sclerosis complex, von Hippel-Lindau disease, Li-Fraumeni syndrome, Cowden disease, Turcot syndrome, nevoid basal cell carcinoma syndrome (Gorlin syndrome) and rhabdoid predisposition syndrome, which are the most common.
authors.affiliation: Department of Pathology, Children's Hospital Agia Sofia, Athens, Greece.
authors.forename: Kalliopi
authors.initials: K
authors.lastname: Stefanaki
authors.forename: George A
authors.initials: GA
authors.lastname: Alexiou
authors.forename: Christina
authors.initials: C
authors.lastname: Stefanaki
authors.forename: Neofytos
authors.initials: N
authors.lastname: Prodromou
mesh_terms: D000818:Animals; D001932:Brain Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics*; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D006801:Humans; D016864:Li-Fraumeni Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D009386:Neoplastic Syndromes, Hereditary / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D009456:Neurofibromatosis 1 / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics*; D013577:Syndrome; D014402:Tuberous Sclerosis / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D006623:von Hippel-Lindau Disease / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics