title: Argonaute regulation: two roads to the same destination.
abstract: Reporting recently in Nature and Nature Structural and Molecular Biology, Shen et al. (2013) and Smibert et al. (2013) uncover mechanisms for Argonaute (Ago) protein regulation. Smibert et al. find that microRNA availability controls Ago levels, and Shen et al. show that epidermal growth factor receptor-mediated Ago2 phosphorylation affects Ago loading.
authors.affiliation: Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Universitätsstrasse 31, 93053 Regensburg, Germany.
authors.forename: Judith
authors.initials: J
authors.lastname: Hauptmann
authors.forename: Gunter
authors.initials: G
authors.lastname: Meister
mesh_terms: D060565:Argonaute Proteins / Q000737:chemistry* / Q000378:metabolism*; D015687:Cell Hypoxia / Q000502:physiology*; D066246:ErbB Receptors / Q000378:metabolism*; D005260:Female; D006801:Humans; D035683:MicroRNAs / Q000378:metabolism*
chemical_list: D060565:Argonaute Proteins; D035683:MicroRNAs; D066246:ErbB Receptors