title: Response to Abadi and Kusters, World J Gastroenterol 19:429-430.
abstract: In a recent study, Rafiei et al, reported a link between a C150T polymorphism in the human inducible nitric oxide gene and Helicobacter pylori infection as a risk factor for gastric cancer among an Iranian population. Subsequently, Abadi and Kusters published a letter to the editor questioning the validity of the study because of a supposed flaw in primer design. Here we respond to the claims of Abadi and Kusters and show that the results reported in the original article are valid.
authors.forename: Alireza
authors.initials: A
authors.lastname: Rafiei
authors.forename: Jeremy J
authors.initials: JJ
authors.lastname: Gilbreath
authors.forename: D Scott
authors.initials: DS
authors.lastname: Merrell
mesh_terms: D005260:Female; D016481:Helicobacter Infections / Q000453:epidemiology*; D016480:Helicobacter pylori / Q000472:pathogenicity*; D006801:Humans; D008297:Male; D052247:Nitric Oxide Synthase Type II / Q000235:genetics*; D011110:Polymorphism, Genetic; D013274:Stomach Neoplasms / Q000453:epidemiology*
chemical_list: D052247:Nitric Oxide Synthase Type II
keywords: Gastric cancer; Helicobacter pylori; Inducible nitric oxide synthetase