title: One-pot construction of 3,3'-bisindolylmethanes through Bartoli indole synthesis.
abstract: A one-pot approach to 3,3'-bisindolylmethane derivatives from nitrobenzene derivatives through the Bartoli indole synthesis was developed, in which the acid used to quench the reaction markedly affected its outcome. Quenching the reaction with concd HCl produced 3,3'-bisindolylmethane in contrast to the formation of 7-substituted indole by quenching with NH4Cl.
authors.affiliation: School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan.
authors.forename: Takumi
authors.initials: T
authors.lastname: Abe
authors.forename: Shuuhei
authors.initials: S
authors.lastname: Nakamura
authors.forename: Reiko
authors.initials: R
authors.lastname: Yanada
authors.forename: Tominari
authors.initials: T
authors.lastname: Choshi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hibino
authors.forename: Minoru
authors.initials: M
authors.lastname: Ishikura
mesh_terms: D002384:Catalysis; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: C512018:1,1-bis(3'-indolyl)methane; D007211:Indoles