title: Clinical study on treatment of cough variant asthma by Chinese medicine.
abstract: OBJECTIVE
  To observe the clinical efficacy and the change of airway responsiveness to Chinese medicine (CM) in treating cough variant asthma (CVA).
  
  
  METHODS
  Ninety-four patients who had confirmed the diagnosis of CVA were selected and randomly assigned to the treatment group and the control group by the blocked randomization method. The ratio of the two groups was 2:1. The treatment group had 63 patients that were treated by CM, lost in 10 cases, 53 patients had finished the trial. The control group had 31 patients that were treated by montelukast tablets and theophylline, lost in 5 cases, 26 patients had finished the trial, two weeks as one therapeutic course. The syndrome efficacy, cough efficacy, symptom score and the airway responsiveness between two groups were observed.
  
  
  RESULTS
  The comparison of the syndrome efficacy: the total effective rate of the treatment group was 90.57% and the control group was 76.92%, and the two groups were significantly different (P<0.05). The comparison of the cough efficacy: the total effective rate of the treatment group was 98.11% and the control group was 80.77%, and the two groups were also significantly different (P<0.05). Syndrome scoring and cough scoring were all significantly lowered, but the airway responsiveness was not significantly lowered.
  
  
  CONCLUSIONS
  The treatment of CM could ease the cough, improve the syndrome, and shows obvious advantages compared with the control group, which is worthy of extensive clinical application.
authors.affiliation: Respiratory Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China. Miaoqing55@yahoo.cn
authors.forename: Qing
authors.initials: Q
authors.lastname: Miao
authors.forename: Peng-Cao
authors.initials: PC
authors.lastname: Wei
authors.forename: Mao-Rong
authors.initials: MR
authors.lastname: Fan
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Zhang
mesh_terms: D000328:Adult; D003371:Cough / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D012137:Respiratory System / Q000473:pathology; D013577:Syndrome; D016896:Treatment Outcome
chemical_list: D004365:Drugs, Chinese Herbal