title: [Bone architecture and strength in diabetes mellitus].
abstract: Increased fracture risks in diabetes mellitus (DM) have been attributed to deteriorated bone quality both in type 1 and 2 DM because increased risks are disproportionate to their bone mineral densities (BMD) . Although still very little is known about bone architecture in type 1 DM, recent advancement in the techniques, such as high-resolution peripheral quantitative CT (HR-pQCT) and trabecular bone score (TBS) , have revealed that, in type 2 DM, bone microstructure is compromised despite preserved BMD, which may account for high fracture risk in DM.
authors.affiliation: Third Department of Medicine, Teikyo University Chiba Medical Center, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Okazaki
mesh_terms: D015519:Bone Density / Q000502:physiology*; D001842:Bone and Bones / Q000473:pathology* / Q000503:physiopathology; D048909:Diabetes Complications / Q000503:physiopathology*; D050723:Fractures, Bone / Q000209:etiology / Q000473:pathology; D006801:Humans; D012307:Risk Factors; D014057:Tomography, X-Ray Computed