title: The regulation and function of microRNAs in kidney diseases.
abstract: MicroRNAs (miRNA) are endogenous short noncoding RNAs, which regulate virtually all major cellular processes by inhibiting target gene expression. In kidneys, miRNAs have been implicated in renal development, homeostasis, and physiological functions. In addition, miRNAs play important roles in the pathogenesis of various renal diseases, including renal carcinoma, diabetic nephropathy, acute kidney injury, hypertensive nephropathy, polycystic kidney disease, and others. Furthermore, miRNAs may have great values as biomarkers in different kidney diseases.
authors.affiliation: Department of Cellular Biology and Anatomy, Medical College of Georgia, Georgia Regents University and Charlie Norwood Veterans Affairs Medical Center, Augusta, GA 30912, USA.
authors.forename: Qingqing
authors.initials: Q
authors.lastname: Wei
authors.forename: Qing-Sheng
authors.initials: QS
authors.lastname: Mi
authors.forename: Zheng
authors.initials: Z
authors.lastname: Dong
mesh_terms: D058186:Acute Kidney Injury / Q000235:genetics / Q000473:pathology; D015415:Biomarkers; D006706:Homeostasis; D006801:Humans; D007674:Kidney Diseases / Q000145:classification / Q000235:genetics* / Q000473:pathology*; D035683:MicroRNAs / Q000235:genetics*
chemical_list: D015415:Biomarkers; D035683:MicroRNAs