title: Adenocarcinoma (somatic-type malignancy) in mature teratoma of anterior mediastinum.
abstract: Mature teratoma is a common anterior mediastinal tumour. However, occurrence of transformed malignant component within it is very rare. We report a case of a 32-year-old female presenting with dry cough and chest pain. Contrast-enhanced computed tomography (CT) showed a large thin-walled cystic lesion measuring 11.4 cm x 10.6 cm x 10.0 cm in the anterior mediastinum. Right postero-lateral thoracotomy was performed and the tumour was completely excised. Histopathological examination of the excised specimen was suggestive of mature teratoma with transformed malignant component, adenocarcinoma (somatic-type malignancy).
authors.affiliation: Department of Pathology, LRS Institute of Tuberculosis and Respiratory Diseases, New Delhi, India. npaliwal1983@gmail.com
authors.forename: Nidhi
authors.initials: N
authors.lastname: Paliwal
authors.forename: Kumud
authors.initials: K
authors.lastname: Gupta
authors.forename: R K
authors.initials: RK
authors.lastname: Dewan
authors.forename: Shalini
authors.initials: S
authors.lastname: Mullick
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000473:pathology*; D013724:Teratoma / Q000473:pathology*; D014057:Tomography, X-Ray Computed