title: Use of a new ocular insert versus conventional mydriasis in cataract surgery.
abstract: BACKGROUND
  To compare the efficacy and safety of a new ocular insert versus conventional mydriasis in cataract surgery.
  
  
  METHODS
  We selected 70 patients undergoing cataract surgery. Thirty five patients (Group 1) received instillation of mydriatic drops (tropicamide 1%, phenylephrine 10%, and cyclopentolate 1%) prior to surgery, and 35 patients (Group 2) had a Mydriasert insert (Théa Pharma) (0.28 mg of tropicamide and 5.4 mg of phenylephrine hydrochloride) placed in the inferior fornix. Pupil size before and after surgery, blood pressure, and heart rate were measured.
  
  
  RESULTS
  Before surgery, pupil diameter was 9.44 ± 1.17 mm in Group 1 and 9.05 ± 1.54 in Group 2 (P > 0.05). Twenty four hours after surgery, pupil diameter was 5.20 ± 1.54 mm in Group 1 and 3.33 ± 1.15 in Group 2 (P < 0.001). There were no statistically significant differences in blood pressure or heart rate between groups.
  
  
  CONCLUSIONS
  The effect of the Mydriasert insert was similar to conventional mydriatic agents. Pupil size was restored to normal faster when using the Mydriasert insert compared with conventional mydriatic agents for pupil dilation.
authors.affiliation: Department of Ophthalmology, Miguel Servet University Hospital, Aragonés Institute of Health Sciences, University of Zaragoza, Isabel la Católica 1-3, 50009 Zaragoza, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Torrón
authors.forename: P
authors.initials: P
authors.lastname: Calvo
authors.forename: O
authors.initials: O
authors.lastname: Ruiz-Moreno
authors.forename: J
authors.initials: J
authors.lastname: Leciñena
authors.forename: A
authors.initials: A
authors.lastname: Pérez-Iñigo
mesh_terms: D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D002387:Cataract Extraction; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D009184:Mydriatics / Q000008:administration & dosage / Q000494:pharmacology*; D011680:Pupil / Q000187:drug effects
chemical_list: D009184:Mydriatics