title: Chasing the ACE of hearts.
abstract: A case study of a patient presenting with acute pulmonary oedema, dynamic ECG changes and a rise in cardiac biomarkers with no evidence of myocardial infarction. The clinical course followed a dynamic and inflammatory disease process with evidence of sarcoidosis on tissue histology. The patient had an excellent clinical response to corticosteroid therapy with minimal evidence of hyperenhancement (focal fibrosis) on cardiac MRI at 6 months. The case highlights the challenges in making a new diagnosis of sarcoidosis where involvement appears limited to the heart and lymphatic system.
authors.affiliation: Conquest Hospital, St Leonards-on-Sea, East Sussex, UK. adsilva@nhs.net
authors.forename: Andrew
authors.initials: A
authors.lastname: D'Silva
authors.forename: Imad
authors.initials: I
authors.lastname: Jassim
authors.forename: John
authors.initials: J
authors.lastname: Greenwood
authors.forename: Konrad
authors.initials: K
authors.lastname: Grosser
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D001241:Aspirin / Q000008:administration & dosage / Q000627:therapeutic use; D000077144:Clopidogrel; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D012507:Sarcoidosis / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D006495:Heparin, Low-Molecular-Weight; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin