title: D-penicillamine-induced glomerulonephritis with crescent formation: Remission following drug discontinuation.
abstract: We report a 71-year-old female who presented with rheumatoid arthritis complicated by proteinuria. She had been receiving D-penicillamine (D-Pc) for two years prior to presentation. A urinalysis showed proteinuria and hematuria which disappeared within 3 months after D-Pc was stopped. The renal histological findings showed focal proliferative glomerulonephritis with crescent formation. A total of 10 cases of D-Pc-induced glomerulonephritis with crescent formation without alveolar hemorrhage have previously been reported in the literature. To the best of our knowledge, this is the first case report in which the patient did not require any treatment.
authors.affiliation: Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Mokuda
authors.forename: M
authors.initials: M
authors.lastname: Onishi
authors.forename: K
authors.initials: K
authors.lastname: Takasugi
keywords: Crescentic glomerulonephritis; D-penicillamine; focal proliferative glomerulonephritis; rheumatoid arthritis