title: A case of eosinophilic cystitis in patients with abdominal pain, dysuria, genital skin hyperemia and slight toxocariasis.
abstract: Eosinophilic cystitis is a rare inflammatory disease with controversial aetiology and treatment. We report the case of a 61-year-old man presented with lower quadrant abdominal pain and lower urinary tract symptoms, non responsive to antibiotics and nonsteroidal antiinflammatory drugs. Physical examination was substantially negative, such as laboratory parameters, microscopic, bacteriological and serological evaluations. Cystoscopy revealed red areas involving the mucosa of the bladder and transurethral biopsies revealed infiltrating eosinophils. The patient was treated with corticosteroids and montelukast sodium with improving of the symptoms, and at 5 weeks postoperative pain score was reduced. After discontinuing corticosteroids dysuria recurred with the development of hyperemia at the genital skin; the specific enzyme-linked immunosorbent assay (ELISA) to detect antibodies against several parasites was slightly positive for Toxocara species. Montelukast sodium was discontinued and corticosteroid therapy was started together with albendazole, with improving of patient&rsquo;s symptoms and pain decreasing after one week.
authors.affiliation: Urology Clinic, University of Verona, Italy. karolinedelia@gmail.com. mariaangela.cerruto@univr.it
authors.forename: Maria Angela
authors.initials: MA
authors.lastname: Cerruto
authors.forename: Carolina
authors.initials: C
authors.lastname: D'Elia
authors.forename: Walter
authors.initials: W
authors.lastname: Artibani
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D015766:Albendazole / Q000627:therapeutic use; D000871:Anthelmintics / Q000627:therapeutic use; D001623:Betamethasone / Q000031:analogs & derivatives / Q000627:therapeutic use; D001706:Biopsy; D003556:Cystitis / Q000209:etiology*; D003558:Cystoscopy; D053159:Dysuria / Q000209:etiology; D004630:Emergencies; D004802:Eosinophilia / Q000209:etiology*; D006801:Humans; D006940:Hyperemia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D014120:Toxocariasis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D000871:Anthelmintics; C011175:betamethasone-17,21-dipropionate; D001623:Betamethasone; D015766:Albendazole