title: Sub-acute deltamethrin and fluoride toxicity induced hepatic oxidative stress and biochemical alterations in rats.
abstract: The current study investigated the effects of deltamethrin, fluoride (F(-)) and their combination on the hepatic oxidative stress and consequent alterations in blood biochemical markers of hepatic damage in rats. Significant hepatic oxidative stress and hepatic damage were observed in the toxicant exposed groups. These changes were higher in the deltamethrin-F(-) co-exposure treatment group, depicting a positive interaction between the two chemicals.
authors.affiliation: Department of Veterinary Pharmacology and Toxicology, Sher-e-Kashmir University of Agricultural Sciences and Technology, Jammu, India. nitinvpt2@gmail.com
authors.forename: Nitin
authors.initials: N
authors.lastname: Dubey
authors.forename: Adil Mehraj
authors.initials: AM
authors.lastname: Khan
authors.forename: Rajinder
authors.initials: R
authors.lastname: Raina
mesh_terms: D000818:Animals; D004785:Environmental Pollutants / Q000633:toxicity*; D004798:Enzymes / Q000097:blood; D005260:Female; D005459:Fluorides / Q000633:toxicity*; D007306:Insecticides / Q000633:toxicity*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology; D008297:Male; D009570:Nitriles / Q000633:toxicity*; D018384:Oxidative Stress / Q000187:drug effects*; D011722:Pyrethrins / Q000633:toxicity*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004785:Environmental Pollutants; D004798:Enzymes; D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; C017180:decamethrin; D005459:Fluorides