title: Hookworm-related cutaneous larva migrans in northern Brazil: resolution of clinical pathology after a single dose of ivermectin.
abstract: To assess the effect of ivermectin on the morbidity caused by hookworm-related cutaneous larva migrans in patients in hyperendemic areas, we treated 92 patients (with 441 tracks in total) from Manaus, Brazil, with single-dose ivermectin (200 µg/kg). Four weeks later, patients had 60 tracks, and the associated morbidity improved significantly.
authors.affiliation: Institute of Microbiology and Hygiene.
authors.forename: Angela
authors.initials: A
authors.lastname: Schuster
authors.forename: Hannah
authors.initials: H
authors.lastname: Lesshafft
authors.forename: Felix
authors.initials: F
authors.lastname: Reichert
authors.forename: Sinesio
authors.initials: S
authors.lastname: Talhari
authors.forename: Silas Guedes
authors.initials: SG
authors.lastname: de Oliveira
authors.forename: Ralf
authors.initials: R
authors.lastname: Ignatius
authors.forename: Hermann
authors.initials: H
authors.lastname: Feldmeier
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000977:Antiparasitic Agents / Q000008:administration & dosage*; D001938:Brazil / Q000453:epidemiology; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases; D005260:Female; D006725:Hookworm Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000469:parasitology; D006801:Humans; D007559:Ivermectin / Q000008:administration & dosage*; D007815:Larva Migrans / Q000188:drug therapy* / Q000453:epidemiology / Q000469:parasitology; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D000977:Antiparasitic Agents; D007559:Ivermectin
keywords: Brazil; HrCLM; clinical pathology; endemic area; ivermectin