title: Insertion of arynes into N-halo bonds: a direct approach to o-haloaminoarenes.
abstract: A new approach to access o-haloaminoarenes has been achieved by insertion of arynes into a nitrogen-halide bond (N-X). This transition-metal-free transformation displays a broad substrate scope of arynes, good compatibility with functional groups, and high regioselectivity. Representative transformations of the o-haloaminoarenes are described to highlight their utility for rapid access to diversely functionalized aminoarene derivatives.
authors.affiliation: Department of Chemistry, Duke University, Durham, North Carolina 27708, USA.
authors.forename: Charles E
authors.initials: CE
authors.lastname: Hendrick
authors.forename: Stacey L
authors.initials: SL
authors.lastname: McDonald
authors.forename: Qiu
authors.initials: Q
authors.lastname: Wang