title: Comparison of continuous local anaesthetic and systemic pain treatment after axillary lymphadenectomy in breast carcinoma patients - a prospective randomized study.
abstract: BACKGROUND
  Acute pain after axillary lymphadenectomy is often related mainly to axillary surgery. The aim of the prospective randomized study was to find out if continuous wound infusion of local anaesthetic reduces postoperative pain, consumption of opioids and the incidence of chronic pain compared to the standard intravenous piritramide analgesia after axillary lymphadenectomy in breast carcinoma patients.
  
  
  METHODS
  Altogether 60 patients were enrolled in the prospective randomized study; half in wound infusion of local anaesthetic and half in the standard (piritramide) group.
  
  
  RESULTS
  In the recovery room and on the first day after surgical procedure, the wound infusion of local anaesthetic group reported less acute and chronic pain, a lower consumption of piritramide and metoclopramide, but their alertness after the surgical procedure was higher compared to the standard group.
  
  
  CONCLUSIONS
  After axillary lymphadenectomy in breast carcinoma patients, wound infusion of local anaesthetic reduces acute pain and enables reduced opioid consumption, resulting in less postoperative sedation and a reduced need for antiemetic drugs. After wound infusion of local anaesthetic there is a statistical trend for reduction of chronic pain.
authors.affiliation: Department of Anaesthesiology, Institute of Oncology, Ljubljana, Ljubljana, Slovenia.
authors.forename: Branka
authors.initials: B
authors.lastname: Strazisar
authors.forename: Nikola
authors.initials: N
authors.lastname: Besic
keywords: breast carcinoma; elastomeric pump; pain treatment; wound infusion of local anaesthetic