title: Duodenal switch for intractable reflux gastroesophagitis after proximal gastrectomy.
abstract: Reflux gastroesophagitis is a common postgastrectomy complication after proximal gastrectomy, and conservative treatments including protease inhibitors and proton pump inhibitors are effective in most patients. Here we report a patient with severe reflux gastroesophagitis after proximal gastrectomy, in whom surgical treatment of duodenal switch was effective. An 80-year-old man complained of intractable heartburn, anorexia, and body weight loss after having undergone proximal gastrectomy, with reconstruction by esophagogastrostomy with valvuloplasty and pyloroplasty, for early gastric cancer 14 months before referral to our department. Oral administration of protease inhibitors and proton pump inhibitors was ineffective. Laboratory evaluation showed poor nutritional status. On endoscopic examination, we noted the redness, bleeding, and multiple erosions in the esophagus and the gastric remnant. He was diagnosed to have severe gastroesophagitis due to reflux of duodenal juice into the gastric remnant and esophagus. We performed duodenal switch to divert duodenal juice from the gastric remnant and esophagus; the duodenum was transected 2 cm distal to the pylorus, the duodenal distal end was closed, and a 50-cm Roux limb from the proximal jejunum was anastomosed to the proximal end of the duodenum. The heartburn disappeared postoperatively, and endoscopic examination revealed marked improvement of the reflux gastroesophagitis. One year postoperatively, the patient is free from symptoms including heartburn. His body weight increased, and laboratory data showed improvement in nutritional status. In conclusion, the duodenal switch may be surgical treatment of choice for intractable reflux gastroesophagitis after proximal gastrectomy.
authors.affiliation: Department of Surgery, Tohoku University Graduate School of Medicine.
authors.forename: Soutoku
authors.initials: S
authors.lastname: Someya
authors.forename: Chikashi
authors.initials: C
authors.lastname: Shibata
authors.forename: Naoki
authors.initials: N
authors.lastname: Tanaka
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Kudoh
authors.forename: Takeshi
authors.initials: T
authors.lastname: Naitoh
authors.forename: Koh
authors.initials: K
authors.lastname: Miura
authors.forename: Michiaki
authors.initials: M
authors.lastname: Unno
mesh_terms: D000369:Aged, 80 and over; D000713:Anastomosis, Roux-en-Y / Q000379:methods*; D004383:Duodenogastric Reflux / Q000601:surgery*; D004942:Esophagitis, Peptic / Q000601:surgery*; D005743:Gastrectomy / Q000009:adverse effects*; D006801:Humans; D008297:Male; D016896:Treatment Outcome