title: Prophylaxis for acute scleral buckle infection using 0.25 % povidone-iodine ocular surface irrigation during surgery.
abstract: To investigate whether repeated washing of the ocular surface with 0.25 % povidone-iodine during scleral buckling surgery minimizes ocular surface bacterial contamination at completion of the procedure. A total of 489 consecutive eyes that underwent scleral buckling at a single institution were categorized into two groups according to the intraoperative ocular surface washing method used during two separate time periods--a group using physiological saline (saline group, 222 consecutive eyes) and a group using 0.25 % povidone-iodine (PI group 267, consecutive eyes). In 37 eyes of each group, ocular surface fluids were sampled at the beginning of surgery and at completion of buckling, and subjected to bacteriological culture. Acute scleral buckle infection occurred in one patient, and was caused by Pseudomonas aeruginosa. The incidence of acute scleral buckle infection was 0.45 % (1/222 eyes) in the saline group, and 0 % in the PI group, with no significant difference (P = 0.4540). The bacterial detection rates in ocular surface fluid at the beginning of surgery were 5.4 % (2/37 eyes) using saline and 8.1 % (3/37 eyes) using povidone-iodine, with no significant difference (P = 0.6433). The rates at completion of buckling were 18.9 % (7/37 eyes) using saline and 0 % (0 eye) using povidone-iodine, with a significant difference (P = 0.0114). Repeated washing of the ocular surface with 0.25 % povidone-iodine during scleral buckling procedure reduced the ocular surface bacterial contamination rate to an extremely low level at completion of buckling, suggesting that this method is useful for the prevention of acute scleral buckle infection.
authors.affiliation: Department of Ophthalmology, School of Medicine, Surugadai Hospital of Nihon University, 1-8-13 Surugadai, Kanda, Chiyodaku, Tokyo, 101-8309, Japan, sshimada@olive.ocn.ne.jp.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Shimada
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakashizuka
authors.forename: Takayuki
authors.initials: T
authors.lastname: Hattori
authors.forename: Kyuen
authors.initials: K
authors.lastname: Otani
authors.forename: Ayumu
authors.initials: A
authors.lastname: Manabe
authors.forename: Yorihisa
authors.initials: Y
authors.lastname: Kitagawa
authors.forename: Mitsuko
authors.initials: M
authors.lastname: Yuzawa
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000379:methods*; D002648:Child; D004203:Disinfection / Q000379:methods*; D015818:Eye Infections, Bacterial / Q000382:microbiology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011206:Povidone-Iodine / Q000627:therapeutic use*; D012591:Scleral Buckling / Q000379:methods*; D007507:Therapeutic Irrigation; D055815:Young Adult
chemical_list: D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine