title: Octreotide for left ventricular assist device-related gastrointestinal hemorrhage: can we stop the bleeding?
abstract: Left ventricular support devices (LVADs) are associated with a propensity toward gastrointestinal bleeding. A postulated mechanism is related to gastrointestinal arteriovenous malformations secondary to nonpulsatile flow. We describe a case of LVAD-related, gastrointestinal bleeding successfully treated with a combination of subcutaneous and intramuscular depot formulations of octreotide.
authors.affiliation: Division of Cardiology, Virginia Commonwealth University, Richmond, Virginia, USA.
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Rennyson
authors.forename: Keyur B
authors.initials: KB
authors.lastname: Shah
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Tang
authors.forename: Vigneshwar
authors.initials: V
authors.lastname: Kasirajan
authors.forename: Sammy
authors.initials: S
authors.lastname: Pedram
authors.forename: William
authors.initials: W
authors.lastname: Cahoon
authors.forename: Rajiv
authors.initials: R
authors.lastname: Malhotra
mesh_terms: D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D006333:Heart Failure / Q000601:surgery; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015282:Octreotide / Q000627:therapeutic use*
chemical_list: D005765:Gastrointestinal Agents; D015282:Octreotide