title: MR-guided stereotactic breast biopsy using a mixed ferromagnetic-nonmagnetic coaxial system with 12- to 18-gauge needles: clinical experience and long-term outcome.
abstract: OBJECTIVE
  This study investigated the clinical application of a magnetic-resonance (MR)-guided breast biopsy (MRBB) system consisting of a nonmagnetic coaxial needle and a ferromagnetic core biopsy needle.
  
  
  METHODS
  MRBB was performed on 70 breast lesions. The biopsy device consisted of a nonmagnetic 14- to 16-gauge coaxial needle and a ferromagnetic 16- to 18-gauge biopsy needle.
  
  
  RESULTS
  Of the 70 lesions, 29 were malignant and 41 nonmalignant. All 29 malignant lesions underwent surgery and were confirmed as malignant at final histology. Of the 41 nonmalignant lesions, 35 underwent follow-up breast MR imaging (mean, 26 ± 19 months), which demonstrated no lesions changes; six lesions underwent surgery because of poor radiological-pathological correlation; of these 6 lesions, 3 were nonmalignant, one was borderline (lobular carcinoma in situ) and two were malignant (well-differentiated tubular carcinoma and infiltrating ductal carcinoma). Sensitivity, specificity, positive and negative predictive values and diagnostic accuracy were, respectively, 93.5%, 100%, 100%, 95.1% and 97.1% if the lobular carcinoma in situ was considered a nonmalignant histological result, and 90.6%, 100%, 100%, 92.7% and 95.7% if the lobular carcinoma in situ was considered malignant.
  
  
  CONCLUSIONS
  MRBB with a ferromagnetic-nonmagnetic coaxial system represented an easy way to perform a biopsy procedure and was easily applicable in the routine clinical setting.
authors.affiliation: Radiology Department, Guglielmo da Saliceto Hospital, Cantone del Cristo, 29100, Piacenza, Italy, belloni.elena@alice.it.
authors.forename: Elena
authors.initials: E
authors.lastname: Belloni
authors.forename: Pietro
authors.initials: P
authors.lastname: Panizza
authors.forename: Silvia
authors.initials: S
authors.lastname: Ravelli
authors.forename: Francesco
authors.initials: F
authors.lastname: De Cobelli
authors.forename: Simone
authors.initials: S
authors.lastname: Gusmini
authors.forename: Claudio
authors.initials: C
authors.lastname: Losio
authors.forename: Isabella
authors.initials: I
authors.lastname: Sassi
authors.forename: Gianluca
authors.initials: G
authors.lastname: Perseghin
authors.forename: Alessandro
authors.initials: A
authors.lastname: Del Maschio
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000295:instrumentation*; D001943:Breast Neoplasms / Q000473:pathology*; D003937:Diagnosis, Differential; D004867:Equipment Design; D005260:Female; D006801:Humans; D053783:Magnetic Resonance Imaging, Interventional; D059346:Magnets; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity