title: Reducing perioperative cardiac morbidity and mortality: is this the right goal?
abstract: OBJECTIVE
  One million people die annually following noncardiac surgery and 4% of patients suffer an adverse cardiac event after surgery. As the number of people having surgery grows, our ability to risk stratify patients becomes more important, particularly in the setting of perioperative myocardial ischemia/necrosis.
  
  
  RESULTS
  In recent publications, an increased troponin following noncardiac surgery has been associated with a higher morbidity/mortality in the perioperative setting. The level of troponin elevation associated with increased morbidity/mortality is now believed to be far lower than was previously considered to be pathologic.
  
  
  CONCLUSIONS
  The presence of troponin elevations following noncardiac surgery, particularly in at-risk patients, may enable practitioners to better identify high-risk patients in the postoperative setting. After recognizing those patients at increased risk for poor outcomes, practitioners can then make interventions, which may decrease the patients' in-hospital, 30-day and potentially long-term mortality.
authors.affiliation: Department of Anesthesiology and Critical Care, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
authors.forename: Emily K
authors.initials: EK
authors.lastname: Gordon
authors.forename: Lee A
authors.initials: LA
authors.lastname: Fleisher
mesh_terms: D015415:Biomarkers / Q000032:analysis; D006801:Humans; D009203:Myocardial Infarction / Q000517:prevention & control; D017202:Myocardial Ischemia / Q000175:diagnosis* / Q000401:mortality / Q000503:physiopathology; D059035:Perioperative Period / Q000401:mortality*; D018570:Risk Assessment; D014336:Troponin / Q000032:analysis*
chemical_list: D015415:Biomarkers; D014336:Troponin