title: Comparison of ocular biometry between eyes with chronic primary angle-closure glaucoma and their fellow eyes with primary angle-closure or primary angle-closure suspect.
abstract: OBJECTIVE
  To compare the eye with chronic primary angle-closure glaucoma (CPACG) with its fellow eye without glaucoma damage and to determine the biometric differences that may predispose to development of CPACG.
  
  
  METHODS
  Consecutive patients diagnosed with CPACG in 1 eye and primary angle-closure (PAC)/primary angle-closure suspected (PACS) in the fellow eye were recruited. The biometric parameters of both the eyes were measured by A-scan ultrasonic biometry and ultrasound biomicroscopy. Comparisons of visual function, baseline intraocular pressure (IOP), and the biometric measurements were made.
  
  
  RESULTS
  Forty-one patients were recruited. Eyes with CPACG had worse visual function, higher baseline IOP, and larger cup-to-disc ratio than their fellow eyes with PAC/PACS (P<0.001). Eyes with CPACG had shallower anterior chamber depths, smaller anterior chamber angles, thinner irises, and longer iris-ciliary process distances than their fellow eyes with PAC/PACS (P<0.05). There were no significant differences in terms of lens thicknesses, axial lengths, lens vault, and trabecular-ciliary process distances.
  
  
  CONCLUSIONS
  Lens thickness, lens location, and axial length do not appear to play a significant role in the progression from PAC/PACS to CPACG. A thin and anterior iris bowing may be related to the progression from PAC/PACS to CPACG.
authors.affiliation: *State Key Laboratory of Ophthalmology, Department of Glaucoma, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China †Center for Advanced Eye Care, Carson City, NV.
authors.forename: Jingjing
authors.initials: J
authors.lastname: Huang
authors.forename: Zhonghao
authors.initials: Z
authors.lastname: Wang
authors.forename: Ziqiang
authors.initials: Z
authors.lastname: Wu
authors.forename: Zuohong
authors.initials: Z
authors.lastname: Li
authors.forename: Kunbei
authors.initials: K
authors.lastname: Lai
authors.forename: Jian
authors.initials: J
authors.lastname: Ge
mesh_terms: D000328:Adult; D000368:Aged; D000867:Anterior Chamber / Q000000981:diagnostic imaging*; D058452:Axial Length, Eye / Q000473:pathology; D001699:Biometry; D002908:Chronic Disease; D002924:Ciliary Body / Q000000981:diagnostic imaging; D003430:Cross-Sectional Studies; D018450:Disease Progression; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000175:diagnosis* / Q000503:physiopathology; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D007498:Iris / Q000000981:diagnostic imaging; D007908:Lens, Crystalline / Q000000981:diagnostic imaging; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis* / Q000503:physiopathology; D014065:Tonometry, Ocular; D014792:Visual Acuity / Q000502:physiology