title: [Dexmedetomidine: new opportunities in anesthesiology].
abstract: Dexmedetomidine is a novel a,-agonist with unique characteristics. The review contains description of main pharmacological and physiological features of this drug. The experience of off-label using of dexmedetomidine in anesthesia is discussed in details. Authors consider that dexmedetomidine can improve anesthesia management in various clinical situations due to specific sedation profile similar to natural human sleep pattern. It can be helpful in neurosurgery in overweight patients or in patients with high cardiac risk as well as in pediatric practice.
authors.forename: A S
authors.initials: AS
authors.lastname: Kulikov
authors.forename: A Yu
authors.initials: AY
authors.lastname: Lubnin
mesh_terms: D058647:Adrenergic alpha-2 Receptor Agonists / Q000008:administration & dosage* / Q000494:pharmacology; D000367:Age Factors; D000758:Anesthesia / Q000379:methods*; D020927:Dexmedetomidine / Q000008:administration & dosage* / Q000494:pharmacology; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage* / Q000494:pharmacology; D056687:Off-Label Use; D050177:Overweight / Q000150:complications; D012307:Risk Factors
chemical_list: D058647:Adrenergic alpha-2 Receptor Agonists; D006993:Hypnotics and Sedatives; D020927:Dexmedetomidine