title: Body composition in urban South Asian women; development of a bioelectrical impedance analysis prediction equation.
abstract: BACKGROUND
  Assessment of body composition plays a significant role in combating chronic disease among South Asians. Accurate assessment of body composition by bioelectrical impedance analysis (BIA) requires population-specific equations which are currently unavailable for urban South Asian women.
  
  
  OBJECTIVE
  To assess validity of direct BIA assessment and selected equations for prediction of total body water (TBW), against Deuterium ((2)H2O) dilution and develop and validate a population-specific TBW equation for urban South Asian women.
  
  
  METHODS
  Data of 80 urban Sri Lankan women (30-45 years) were used for this analysis. Body composition was assessed by (2)H2O dilution (reference) and BIA. Available BIA equations were assessed for validity. A new TBW equation was generated and validated.
  
  
  RESULTS
  Direct BIA measurements and other equations did not meet validation criteria in predicting TBW. TBW by the new equation (TBW = 3.443 + 0.342 × (height(2)/impedance) + 0.176 × weight) correlated (p < 0.001) with TBW by reference method. TBW using the new equation was not significantly different (25.30 ± 2.4 kg) from the reference (25.32 ± 2.7 kg).
  
  
  CONCLUSIONS
  Direct use of TBW by instrument and existing equations are less suitable for this population. The new TBW equation is suitable for body composition assessment in urban South Asian women.
authors.affiliation: Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Colombo, Kinsey Road, Colombo 8, Sri Lanka.
authors.forename: Indu
authors.initials: I
authors.lastname: Waidyatilaka
authors.forename: Pulani
authors.initials: P
authors.lastname: Lanerolle
authors.forename: Maduka
authors.initials: M
authors.lastname: de Lanerolle-Dias
authors.forename: Sunethra
authors.initials: S
authors.lastname: Atukorala
authors.forename: Angela
authors.initials: A
authors.lastname: de Silva
mesh_terms: D000328:Adult; D001823:Body Composition; D001834:Body Water / Q000378:metabolism*; D003903:Deuterium / Q000378:metabolism; D017097:Electric Impedance; D005260:Female; D006801:Humans; D007201:Indicator Dilution Techniques; D008875:Middle Aged; D008954:Models, Biological; D013188:Sri Lanka; D014505:Urban Population; D044465:White People
chemical_list: D003903:Deuterium