title: Electrochemical glucose biosensor based on nickel oxide nanoparticle-modified carbon paste electrode.
abstract: In the present work, we designed an amperometric glucose biosensor based on nickel oxide nanoparticles (NiONPs)-modified carbon paste electrode. The biosensor was prepared by incorporation of glucose oxidase and NiONPs into a carbon paste matrix. It showed good analytical performances such as high sensitivity (367 μA mmolL(-1)) and a wide linear response from 1.9×10(-3) mmolL(-1) to 15.0 mmolL(-1) with a limit of detection (0.11 μmolL(-1)). The biosensor was used for the determination of glucose in human serum samples. The results illustrate that NiONPs have enormous potential in the construction of biosensor for determination of glucose.
authors.affiliation: Faculty of Science, Department of Chemistry, Ankara University , Ankara , Turkey.
authors.forename: Ceren
authors.initials: C
authors.lastname: Erdem
authors.forename: Derya Koyuncu
authors.initials: DK
authors.lastname: Zeybek
authors.forename: Gözde
authors.initials: G
authors.lastname: Aydoğdu
authors.forename: Bülent
authors.initials: B
authors.lastname: Zeybek
authors.forename: Sule
authors.initials: S
authors.lastname: Pekyardımcı
authors.forename: Esma
authors.initials: E
authors.lastname: Kılıç
mesh_terms: D001234:Aspergillus niger / Q000201:enzymology; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D004563:Electrochemistry; D004566:Electrodes; D004800:Enzymes, Immobilized / Q000737:chemistry / Q000378:metabolism; D005947:Glucose / Q000032:analysis* / Q000737:chemistry; D005949:Glucose Oxidase / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D053758:Nanoparticles / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*; D015203:Reproducibility of Results; D013696:Temperature
chemical_list: D004800:Enzymes, Immobilized; D002244:Carbon; D009532:Nickel; C028007:nickel monoxide; D005949:Glucose Oxidase; D005947:Glucose
keywords: amperometric glucose biosensor; carbon paste electrode; glucose oxidase; nickel oxide nanoparticles