title: Difference in quality of life, fatigue and societal participation between living and deceased donor kidney transplant recipients.
abstract: Purpose of this study was to assess whether living (LD) and deceased donor (DD) kidney transplant recipients differ in health-related quality of life (HRQoL), fatigue and societal participation, depending on time since transplantation and after adjustment for clinical and demographic variables. A questionnaire study was performed among 309 LD and 226 DD recipients (response rate 74% and 61%) transplanted between 1997 and 2009. After adjustment for age, sex, and education, LD recipients transplanted less than or equal to five yr ago experienced better HRQoL than DD recipients on the domains' role limitations due to physical problems, general health perception, and on the physical component summary score (all p < 0.05) and a better societal participation (all subscales, p < 0.05). No differences were found in the mental health domains. The LD recipients also had better renal clearance than DD recipients (62.1 vs. 55.9 mL/min, p = 0.01). After additional adjustment for renal clearance, the differences in HRQoL and societal participation between LD and DD recipients remained. No differences were found in recipients transplanted more than five yr ago. We conclude that LD recipients on average have better HRQoL and societal participation than DD recipients, in the first years after transplantation.
authors.affiliation: Department of Medical Decision Making, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Ingrid B
authors.initials: IB
authors.lastname: de Groot
authors.forename: J Iraida E
authors.initials: JI
authors.lastname: Veen
authors.forename: Paul J M
authors.initials: PJ
authors.lastname: van der Boog
authors.forename: Sandra
authors.initials: S
authors.lastname: van Dijk
authors.forename: Anne M
authors.initials: AM
authors.lastname: Stiggelbout
authors.forename: Perla J
authors.initials: PJ
authors.lastname: Marang-van de Mheen
mesh_terms: D002102:Cadaver; D005221:Fatigue; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006085:Graft Survival; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery*; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000523:psychology*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011379:Prognosis; D011788:Quality of Life; D006435:Renal Dialysis; D012189:Retrospective Studies; D012307:Risk Factors; D012919:Social Behavior; D011795:Surveys and Questionnaires
keywords: deceased donor kidney transplant recipient; fatigue; health-related quality of life; kidney transplantation; living donor kidney transplant recipient; societal participation