title: [Regional molecular genetics centers in thoracic oncology: what and who should be tested?].
abstract: Management of NSCLC patients is more and more individualized especially on the base of bioguided treatments. In order to guarantee an access for all the patients too this type of strategy, the French NCI supports since 2006 a nationwide network of 28 regional genetics center. The financial support is based on public funds. The French NCI recommends today the assessment of seven biomarkers for all stage IV non squamous NSCLC patients. Due to financial and technical reasons, this recommendation must be followed. However, the molecular profiling of lung cancer patients would ideally be extended across all stages and all histological types of the disease in order to improve our knowledge in this field and provides the patient with an opportunity to access a bioguided treatment as frequently as possible.
authors.affiliation: AP-HM, Aix-Marseille Université, Service d'Oncologie Multidisciplinaire et Innovations Thérapeutiques, Chemin des Bourrely, 13915 Marseille cedex 20, France. Fabrice.BARLESI@ap-hm.fr
authors.forename: Fabrice
authors.initials: F
authors.lastname: Barlesi
authors.forename: Pascale
authors.initials: P
authors.lastname: Tomasini
authors.forename: Frédéric
authors.initials: F
authors.lastname: Fina
authors.forename: Véronique
authors.initials: V
authors.lastname: Secq
authors.forename: Laurent
authors.initials: L
authors.lastname: Greillier
authors.forename: Isabelle
authors.initials: I
authors.lastname: Nanni-Metellus
authors.forename: Stéphane
authors.initials: S
authors.lastname: Garcia
authors.forename: L'houcine
authors.initials: L
authors.lastname: Ouafik
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000235:genetics*; D005602:France; D005819:Genetic Markers; D005826:Genetics, Medical / Q000458:organization & administration* / Q000592:standards; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics*; D008495:Medical Oncology / Q000458:organization & administration / Q000592:standards; D018579:Patient Selection; D057285:Precision Medicine; D012041:Regional Medical Programs / Q000458:organization & administration* / Q000592:standards
chemical_list: D005819:Genetic Markers
keywords: bioguided treatment; french NCI; lung cancer; molecular genetics center; molecular profiling; personalized therapy