title: Spontaneously remitted pulmonary arterial hypertension associated with the herbal medicine "bofutsushosan".
abstract: Although the link between pulmonary arterial hypertension (PAH) and exposure to certain drugs has already been identified, we herein present the first case of herbal medicine-associated PAH in which the patient demonstrated spontaneous remission. A 38-year-old woman took the herbal medicine "bofutsushosan" for two weeks then stopped taking it due to exertional dyspnea. However, her dyspnea continued, and right heart catheterization revealed a mean pulmonary arterial pressure of 41 mmHg with a normal wedge pressure. Several months after treatment with oxygen therapy, the patient's dyspnea disappeared, and her pulmonary arterial pressure normalized. Further studies focusing on susceptibility factors to drug-induced pulmonary arterial hypertension are needed.
authors.affiliation: Department of Respirology, Graduate School of Medicine, Chiba University, Japan. yoliri1001@chiba-u.jp
authors.forename: Yoriko
authors.initials: Y
authors.lastname: Sakurai
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Tanabe
authors.forename: Ayumi
authors.initials: A
authors.lastname: Sekine
authors.forename: Rintaro
authors.initials: R
authors.lastname: Nishimura
authors.forename: Takayuki
authors.initials: T
authors.lastname: Jujo
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kawasaki
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Sugiura
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Sakao
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Kasahara
authors.forename: Koichiro
authors.initials: K
authors.lastname: Tatsumi
mesh_terms: D000328:Adult; D004365:Drugs, Chinese Herbal / Q000009:adverse effects*; D065627:Familial Primary Pulmonary Hypertension; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000139:chemically induced* / Q000175:diagnosis*; D012075:Remission, Spontaneous
chemical_list: D004365:Drugs, Chinese Herbal; C098310:bofu-tsusho-san