title: Acute peritoneal dialysis in the newborn period: a 7-year single-center experience at tertiary neonatal intensive care unit in Turkey.
abstract: OBJECTIVE
  To evaluate the underlying causes and outcomes of neonates who underwent acute peritoneal dialysis (APD).
  
  
  METHODS
  This report describes a 7-year experience with APD in 77 neonates.
  
  
  RESULTS
  Underlying causes requiring APD were acute tubular necrosis (ATN; n = 53), inborn error of metabolism (n = 18), bilateral renal vein thrombosis (n = 3), obstructive uropathy (n = 2; posterior urethral valve and neurogenic bladder), and bilateral renal artery thrombosis (n = 1). Fifteen of the 53 patients developed post-cardiac surgery ATN. The mean dialysis duration was 6.2 ± 10.7 days (range 1 to 90 days). Complications of procedure were hyperglycemia (n = 35), leaking of dialysate (n = 13), peritonitis (n = 10), catheter obstruction (n = 3), bleeding when inserting the catheter (n = 3), exit site infection (n = 2), and bowel perforation (n = 1). There were 57 deaths (74%) in this high-risk group due to underling causes. Of the 20 survivors, 16 patients showed a full renal recovery, but mild chronic renal failure developed in 1 patient and proteinuria with/without hypertension in 3 patients.
  
  
  CONCLUSIONS
  Peritoneal dialysis is an effective means of renal replacement therapy in the neonatal period in the management of metabolic disturbances as well as renal failure. Although major complications of procedure are not so common, these patients have high mortality rates due to the serious nature of the primary causes.
authors.affiliation: Department of Neonatology, Dr. Sami Ulus Maternity and Children Hospital, Ankara, Turkey.
authors.forename: Nilay
authors.initials: N
authors.lastname: Hakan
authors.affiliation: Department of Neonatology, Dr. Sami Ulus Maternity and Children Hospital, Ankara, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Aydin
authors.affiliation: Department of Neonatology, Dr. Sami Ulus Maternity and Children Hospital, Ankara, Turkey.
authors.forename: Aysegul
authors.initials: A
authors.lastname: Zenciroglu
authors.affiliation: Department of Pediatric Nephrology, Dr. Sami Ulus Maternity and Children Hospital, Ankara, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Aydog
authors.affiliation: Department of Pediatric Surgery, Dr. Sami Ulus Maternity and Children Hospital, Ankara, Turkey.
authors.forename: Derya
authors.initials: D
authors.lastname: Erdogan
authors.affiliation: Department of Neonatology, Dr. Sami Ulus Maternity and Children Hospital, Ankara, Turkey.
authors.forename: Belma Saygili
authors.initials: BS
authors.lastname: Karagol
authors.affiliation: Department of Neonatology, Dr. Sami Ulus Maternity and Children Hospital, Ankara, Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Dursun
authors.affiliation: Department of Neonatology, Dr. Sami Ulus Maternity and Children Hospital, Ankara, Turkey.
authors.forename: Nurullah
authors.initials: N
authors.lastname: Okumus
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000628:therapy*; D061807:Catheter Obstruction / Q000209:etiology; D015331:Cohort Studies; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D006943:Hyperglycemia / Q000209:etiology; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D007673:Kidney Cortex Necrosis / Q000150:complications; D007674:Kidney Diseases / Q000150:complications; D008297:Male; D008661:Metabolism, Inborn Errors / Q000150:complications; D010530:Peritoneal Dialysis / Q000009:adverse effects / Q000379:methods*; D010538:Peritonitis / Q000209:etiology; D012078:Renal Artery Obstruction / Q000150:complications; D012082:Renal Veins; D062606:Tertiary Care Centers; D013927:Thrombosis / Q000150:complications; D013997:Time Factors; D014421:Turkey