title: Hematologic alterations in patients with functionally univentricular hearts.
abstract: Coagulation factor deficiencies may predispose patients with functionally univentricular hearts to bleeding tendencies preoperatively and perioperatively. Postoperatively, this is altered to a prothrombotic predisposition in these patients. Early and late thromboembolic events secondary to a prothrombotic state following univentricular repair contribute to significant morbidity after establishment of the Fontan circulation. Anticoagulation following univentricular repair is advocated but its benefits are controversial.
authors.affiliation: Division of Congenital Cardiac Surgery, Fortis Escorts Heart Research Institute, New Delhi, India.
authors.forename: Zeena
authors.initials: Z
authors.lastname: Makhija
authors.forename: Rajesh
authors.initials: R
authors.lastname: Sharma
keywords: Fontan; coagulation; single ventricle