title: Cancer concepts and principles: primer for the interventional oncologist-part II.
abstract: This is the second of a two-part overview of the fundamentals of oncology for interventional radiologists. The first part focused on clinical trials, basic statistics, assessment of response, and overall concepts in oncology. This second part aims to review the methods of tumor characterization; principles of the oncology specialties, including medical, surgical, radiation, and interventional oncology; and current treatment paradigms for the most common cancers encountered in interventional oncology, along with the levels of evidence that guide these treatments.
authors.affiliation: Department of Radiology and Division of Interventional Oncology, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Ryan
authors.initials: R
authors.lastname: Hickey
authors.forename: Michael
authors.initials: M
authors.lastname: Vouche
authors.forename: Daniel Y
authors.initials: DY
authors.lastname: Sze
authors.forename: Elias
authors.initials: E
authors.lastname: Hohlastos
authors.forename: Jeremy
authors.initials: J
authors.lastname: Collins
authors.forename: Todd
authors.initials: T
authors.lastname: Schirmang
authors.forename: Khairuddin
authors.initials: K
authors.lastname: Memon
authors.forename: Robert K
authors.initials: RK
authors.lastname: Ryu
authors.forename: Kent
authors.initials: K
authors.lastname: Sato
authors.forename: Richard
authors.initials: R
authors.lastname: Chen
authors.forename: Ramona
authors.initials: R
authors.lastname: Gupta
authors.forename: Scott
authors.initials: S
authors.lastname: Resnick
authors.forename: James
authors.initials: J
authors.lastname: Carr
authors.forename: Howard B
authors.initials: HB
authors.lastname: Chrisman
authors.forename: Albert A
authors.initials: AA
authors.lastname: Nemcek
authors.forename: Robert L
authors.initials: RL
authors.lastname: Vogelzang
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Lewandowski
authors.forename: Riad
authors.initials: R
authors.lastname: Salem
mesh_terms: D055011:Ablation Techniques; D002404:Catheterization; D057510:Endovascular Procedures; D019317:Evidence-Based Medicine; D006801:Humans; D008495:Medical Oncology / Q000379:methods*; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D017410:Practice Guidelines as Topic; D015641:Radiography, Interventional; D016896:Treatment Outcome
keywords: 5-FU; 5-fluorouracil; AFP; AJCC; American Joint Committee on Cancer; BCLC; Barcelona Clinic Liver Cancer; CRC; CapeOx; DEB; DEBIRI; EASL; EGFR; European Association for Study of the Liver; FOLFIRI; FOLFOX; HCC; IRE; NCCN; NCI; NET; NSCLC; National Cancer Institute; National Comprehensive Cancer Network; PV; RF; RT; VEGFR; capecitabine/oxaliplatin; colorectal cancer; drug-eluting bead; drug-eluting beads with irinotecan; epidermal growth factor receptor; hepatocellular carcinoma; irinotecan/5-fluorouracil/leucovorin; irreversible electroporation; neuroendocrine tumor; non–small-cell lung cancer; oxaliplatin/5-fluorouracil/leucovorin; portal vein; radiation therapy; radiofrequency; vascular endothelial growth factor receptor; α-fetoprotein