title: Successful surgical resection in non-lesional operculo-insular epilepsy without intracranial monitoring.
abstract: Pre-operative assessment and surgical management of patients with non-lesional extratemporal epilepsy remain challenging due to a lack of precise localisation of the epileptic zone. In most cases, invasive recording with depth or subdural electrodes is required. Here, we describe the case of 6.5-year-old girl who underwent comprehensive non-invasive phase I video-EEG investigation for drug-resistant epilepsy, including electric source and nuclear imaging. Left operculo-insular epilepsy was diagnosed. Post-operatively, she developed aphasia which resolved within one year, corroborating the notion of enhanced language plasticity in children. The patient remained seizure-free for more than three years.
authors.affiliation: Department of Neurology, Chisinau, Moldova.
authors.forename: Vitalie
authors.initials: V
authors.lastname: Chiosa
authors.forename: Cristina
authors.initials: C
authors.lastname: Granziera
authors.forename: Laurent
authors.initials: L
authors.lastname: Spinelli
authors.forename: Claudio
authors.initials: C
authors.lastname: Pollo
authors.forename: Eliane
authors.initials: E
authors.lastname: Roulet-Perez
authors.forename: Stanislav
authors.initials: S
authors.lastname: Groppa
authors.forename: Margitta
authors.initials: M
authors.lastname: Seeck
mesh_terms: D001039:Aphasia, Broca / Q000209:etiology; D002648:Child; D004569:Electroencephalography; D017034:Epilepsy, Frontal Lobe / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D019635:Neurosurgical Procedures / Q000009:adverse effects / Q000379:methods*
keywords: epilepsy surgery; insular epilepsy; presurgical assessment; seizure