title: Heritability of thirty cephalometric parameters on monozygotic and dizygotic twins: twin study method.
abstract: Genetic mechanisms are already predominant during embryonic craniofacial morphogenesis, but environment is also thought to influence dentofacial morphology postnatally, particularly during facial growth. A better understanding of the relative effects of genes and environment on dentofacial and occlusal parameters should improve our knowledge on the etiology of orthodontic disorders and therefore also on the possibilities and limitations of the orthodontic treatment and treatment planning. The aim of the present study is to explore the genetic and environmental influence on craniofacial dimensions in a group of 19 pairs of twins using the twin study method. The twin study carried out here clearly indicates that craniofacial matrix is under substantial genetic control and the redirection of a basic growth pattern may be modified only within biological limits which are harmonious for the patient.
authors.affiliation: Department of Orthodontics, Kalinga Institute of Dental Sciences, Patia, Bhubaneswar, Odisha, India. siriorth@gmail.com
authors.forename: Gojja
authors.initials: G
authors.lastname: Sreedevi
authors.forename: Baratam
authors.initials: B
authors.lastname: Srinivas
authors.forename: T Praveen Kumar
authors.initials: TP
authors.lastname: Reddy
authors.forename: C M S Krishna
authors.initials: CM
authors.lastname: Prasad
authors.forename: B Sunil
authors.initials: BS
authors.lastname: Kumar
authors.forename: R
authors.initials: R
authors.lastname: Satish
mesh_terms: D000293:Adolescent; D000328:Adult; D000465:Algorithms; D002508:Cephalometry; D003878:Dermatoglyphics / Q000145:classification; D005147:Facial Bones / Q000033:anatomy & histology; D005260:Female; D059647:Gene-Environment Interaction; D006801:Humans; D007180:Incisor / Q000033:anatomy & histology; D040582:Inheritance Patterns / Q000235:genetics*; D008046:Lip / Q000033:anatomy & histology; D008297:Male; D008334:Mandible / Q000033:anatomy & histology; D010159:Palate / Q000033:anatomy & histology; D010641:Phenotype; D010781:Photography; D012886:Skull / Q000033:anatomy & histology; D019291:Skull Base / Q000033:anatomy & histology; D014429:Twins, Dizygotic / Q000235:genetics*; D014430:Twins, Monozygotic / Q000235:genetics*; D014716:Vertical Dimension; D055815:Young Adult