title: Stress hormone response to various anaesthetic techniques during thyroidectomy.
abstract: BACKGROUND
  Thyroidectomy is among the most frequently performed procedures in endocrine surgery. The hormonal response to surgery and anaesthesia depends in part on the anaesthetic techniques used; therefore, we measured serum concentrations of TSH, fT4, and fT3 in patients scheduled for elective thyroidectomy under TIVA or VIMA.
  
  
  METHODS
  Seventy-eight adult patients, of both sexes, with non-toxic or hyperthyroid nodular goitre, were divided into groups with regard to the goitre type and the technique of anaesthesia used during thyroid surgery. Serum concentrations of TSH, fT4, and fT3, were measured and the surgical stress was estimated using the E-PASS scale.
  
  
  RESULTS
  In the groups examined, the mean serum concentrations of TSH remained unchanged during the period of observation. The initially high fT4 and fT3 concentrations gradually decreased, reaching their lowest level on the fourth day after surgery.
  
  
  CONCLUSIONS
  [corrected] Both VIMA and TIVA can be regarded as safe techniques of anaesthesia for thyroidectomy.
authors.affiliation: Department of Anaesthesiology and Intensive Therapy, Medical University of Białystok.
authors.forename: Ewa
authors.initials: E
authors.lastname: Grycz
authors.forename: Andrzej
authors.initials: A
authors.lastname: Siemiątkowski
mesh_terms: D000328:Adult; D000768:Anesthesia, General / Q000009:adverse effects / Q000379:methods*; D000777:Anesthetics / Q000008:administration & dosage; D017558:Elective Surgical Procedures / Q000379:methods; D005260:Female; D006042:Goiter / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D013312:Stress, Physiological / Q000502:physiology; D013965:Thyroidectomy / Q000379:methods*; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood*; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood*
chemical_list: D000777:Anesthetics; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine