title: Acute liver failure associated with propylthiouracil in a pregnant 26-year-old woman.
abstract: It seems appropriate to use propylthiouracil to treat maternal hyperthyroidism during the first trimester of pregnancy. We present the case of a 26-year-old woman with acute liver failure associated with propylthiouracil during the first trimester of pregnancy. She was successfully treated without liver transplantation. Attention should be paid to the possible occurrence of propylthiouracil-induced hepatotoxicity even during the first trimester of pregnancy.
authors.affiliation: Department of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, Chiba, Japan.
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Miyamura
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Kanda
authors.forename: Shoko
authors.initials: S
authors.lastname: Minemura
authors.forename: Masato
authors.initials: M
authors.lastname: Nakamura
authors.forename: Shingo
authors.initials: S
authors.lastname: Nakamoto
authors.forename: Xia
authors.initials: X
authors.lastname: Jiang
authors.forename: Shuang
authors.initials: S
authors.lastname: Wu
authors.forename: Shin
authors.initials: S
authors.lastname: Yasui
authors.forename: Makoto
authors.initials: M
authors.lastname: Arai
authors.forename: Osamu
authors.initials: O
authors.lastname: Yokosuka
keywords: Acute liver failure; First trimester; Immune tolerance; Pregnancy; Propylthiouracil