title: Unexpected discovery of massive liver echinococcosis. A clinical, morphological, and functional diagnosis.
abstract: We report a case of symptomatic massive liver echinococcosis due to Echinococcus granulosus, unexpectedly found in a 34 year old woman living in Apulia, Italy. Based on size (max diameter 18 cm), clinical presentation, geographical area, and natural history of echinococcosis, we estimate that the initial infection should have occurred 9-20 yrs before. Presenting symptoms were those of typical mass effect with RUQ pain, pruritus, malaise, and recent weight loss. Abdominal ultrasound diagnosis of probable echinococcal cyst was subsequentely confirmed by positive serology and further detailed by radiological imaging. The cyst was massively occupying subdiaphragmatic liver segments and extending to the omentum and the stomach. The characteristics of the lesion were compatible with the WHO 2003 classification type CE2l, indicating a large active fertile cyst with daughter cysts. The cyst was successfully treated with medical therapy followed by surgery. The prevalence, diagnostic workup, management, and costs of echinococcosis are discussed in this case presentation.
authors.affiliation: Clinica Medica A. Murri, Department of Biomedical Sciences and Human Oncology, University Medical School, Bari, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Bonfrate
authors.forename: F
authors.initials: F
authors.lastname: Giuliante
authors.forename: G
authors.initials: G
authors.lastname: Palasciano
authors.forename: J T
authors.initials: JT
authors.lastname: Lamont
authors.forename: P
authors.initials: P
authors.lastname: Portincasa
mesh_terms: D000328:Adult; D004444:Echinococcosis, Hepatic / Q000175:diagnosis* / Q000469:parasitology / Q000473:pathology / Q000628:therapy; D005260:Female; D006790:Host-Parasite Interactions; D006801:Humans; D008099:Liver / Q000469:parasitology / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D011237:Predictive Value of Tests; D012720:Severity of Illness Index; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome