title: [Determination of 24 minerals in human milk by inductively coupled plasma mass spectrometry with microwave digestion].
abstract: OBJECTIVE
  To determine the levels of 24 minerals in human milk by inductively coupled plasma mass spectrometry with microwave digestion.
  
  
  METHODS
  The samples were digested by microwave. The contents of minerals were determined by inductively coupled plasma mass spectrometry. The standard reference minerals of 1849a and 1568a from National Institute of Science and Technology were used for quality control. The accuracy and reproduability for this method were evaluated with mix standards and 1849a and 1568a standard reference materials.
  
  
  RESULTS
  The ranges of the levels of sodium, magnesium, phosphorus, potassium, calcium, aluminum, chromium, arsenic, selenium, iron, zinc, manganese, copper, molybdenum, vanadium, cobalt, nickel, gallium, cadmium, silver, strontium, cesium, barium, lead in human milk was 34.97-415.83 mg/kg, 19.00-39.52 mg/kg, 102.13-274.53 mg/kg, 351.19-713.99 mg/kg, 180.08-349.64 mg/kg, 0.06-0.44 mg/kg, 0.9-7.37 microg/kg, 0.92-2.72 microg/kg, 0.20-21.15 microg/kg, 0.10-0.70 mg/kg, 0.56-3.25 mg/kg, 3.00-16.12 micro.g/kg, 62.16-591.69 microg/kg, 0.02-6.91 microg/kg, 5.99-13.70 microg/kg, 0.07-2.11 microg/kg, 0.77-209.26 microg/kg, 0.005-0.28 microg/kg, 0.02-0.23 microg/kg, 0.02-0.71 microg/kg, 36.89-132.26 microg/kg, 0.01-4.72 microg/kg, 0.83-28.16 microg/kg, 2.5-5.3 microg/kg, respectively. The levels of minerals in human milk in present study were consisted with other similar studies.
  
  
  CONCLUSIONS
  The experiment examined the levels of minerals in human milk satisfactorily. The method has high accuracy and good reproducibility, which could be used for understanding the levels of minerals in human milk.
authors.affiliation: National Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing, China. s_zhongqing@163.com
authors.forename: Zhongqing
authors.initials: Z
authors.lastname: Sun
authors.forename: Bing
authors.initials: B
authors.lastname: Yue
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Yang
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Li
authors.forename: Yongning
authors.initials: Y
authors.lastname: Wu
authors.forename: Shian
authors.initials: S
authors.lastname: Yin
mesh_terms: D006801:Humans; D008274:Magnesium / Q000032:analysis; D008872:Microwaves; D008895:Milk, Human / Q000737:chemistry*; D008903:Minerals / Q000032:analysis*; D010758:Phosphorus / Q000032:analysis; D012964:Sodium / Q000032:analysis; D013054:Spectrophotometry, Atomic / Q000379:methods*
chemical_list: D008903:Minerals; D010758:Phosphorus; D012964:Sodium; D008274:Magnesium