title: Relation between serum PAPP-A level and umbilical cord thickness during first trimester of pregnancy.
abstract: OBJECTIVE
  To evaluate the relation between umbilical cord diameter versus pregnancy associated plasma protein-A (PAPP-A) level in first trimester women.
  
  
  METHODS
  Cord diameter were measured and patients were divided into two groups according to frequency distribution analysis as below or above 3.7 mm for free loop diameter (FCD) and below or above 3.4 mm for cord measurement at umbilicus (ACD). Groups were compared with each other.
  
  
  RESULTS
  Strong correlations were found between ACD versus PAPP-A.
  
  
  CONCLUSIONS
  By using strong correlation between ACD versus PAPP-A, it may be possible to reduce unnecessary amniocentesis due to false positive screening results.
authors.affiliation: Department of ObGyn, Sevket Yılmaz Education and Research Hospital , Bursa , Turkey .
authors.forename: Muzeyyen
authors.initials: M
authors.lastname: Duran
authors.forename: Aydın
authors.initials: A
authors.lastname: Köşüş
authors.forename: Nermin
authors.initials: N
authors.lastname: Köşüş
authors.forename: Nilgün Ö
authors.initials: NÖ
authors.lastname: Turhan
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D005865:Gestational Age; D006801:Humans; D062145:Maternal Serum Screening Tests; D011247:Pregnancy; D011261:Pregnancy Trimester, First / Q000097:blood*; D011266:Pregnancy-Associated Plasma Protein-A / Q000378:metabolism*; D011446:Prospective Studies; D012044:Regression Analysis; D016216:Ultrasonography, Prenatal; D014470:Umbilical Cord / Q000033:anatomy & histology* / Q000000981:diagnostic imaging
chemical_list: D015415:Biomarkers; D011266:Pregnancy-Associated Plasma Protein-A