title: [Molecular-epidemiological monitoring of enterovirus circulation in the Far East and Zabaikalye].
abstract: 6 year molecular-biological monitoring of enteroviruses in the Far East and Zabaikalye was carried out. Nucleotide sequence of 125 strains was determined from 2006 to 2011. Molecular analysis was carried out in VP1 virus genome region. Phylogenetic interactions for ECHO-6, ECHO-30, ECHO-11, Coxsackie B-5 (CB-5), Coxsackie B-1 (CB-1) and Coxsackie A-9 (CA-9) were analyzed. Highly dynamic epidemiology was shown to be inherent for ECHO-6 and ECHO-30 viruses and is characterized by genetic heterogeneity and consequent change of virus variants. On the contrary a relative stability of circulating genotypes is intrinsic for CB-1, CB-5 and ECHO-11 enteroviruses. The results of molecular-biological studies indicate frequent introduction of new enterovirus variants from countries of Europe and Asia.
authors.forename: O E
authors.initials: OE
authors.lastname: Trotsenko
authors.forename: A N
authors.initials: AN
authors.lastname: Lukashev
authors.forename: T N
authors.initials: TN
authors.lastname: Karavianskaia
authors.forename: V I
authors.initials: VI
authors.lastname: Reznik
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Sapega
authors.forename: V O
authors.initials: VO
authors.lastname: Kotova
authors.forename: E N
authors.initials: EN
authors.lastname: Amiaga
authors.forename: P V
authors.initials: PV
authors.lastname: Korita
mesh_terms: D004770:Enterovirus / Q000235:genetics*; D004769:Enterovirus Infections / Q000453:epidemiology* / Q000235:genetics* / Q000635:transmission; D062665:Epidemiological Monitoring; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D017720:Molecular Epidemiology; D012800:Siberia / Q000453:epidemiology