title: [Application of Onodera prognostic nutrition index in prognostic evaluation of elderly patients with colorectal cancer].
abstract: OBJECTIVE
  To study the applied valuation of Onodera prognostic nutrition index (Onodera index) in elderly patients with colorectal cancer.
  
  
  METHODS
  Onodera indexes of 163 elderly patients with colorectal cancer were calculated and these patients were divided into better-nourished group (Onodera index ≥45) and under-nourished group (Onodera index <45). Correlations of Onodera index with general data, operation type, postoperative complication, recovery of gastrointestinal function, clinicopathological feature and prognosis were analyzed. Cox proportional hazards model was also established to identify the independent prognostic factors for prognosis of elderly patients with colorectal cancer.
  
  
  RESULTS
  Patients in better-nourished group had significantly higher radical resection rate [90.9% (70/77) vs. 62.8% (54/86), P<0.01], lower postoperative complication rate [17.1% (12/70) vs. 53.7% (29/54), P<0.01] and earlier postoperative defecation [(3.09±1.14) d vs. (3.43±1.98) d, P<0.05] than those in under-nourished group. Onodera index was found to be related to age, tumor location, tumor size, and operation type (all P<0.05). Better-nourished group had significantly better survival than worse-nourished group (5-year survival rate: 64% vs. 24%, P<0.01). Onodera index was identified as an independent prognostic factor for elderly patients with colorectal cancer (RR=0.888, 95%CI:0.800-0.985, P=0.025).
  
  
  CONCLUSIONS
  Onodera index is a valuable clinical marker in preoperative estimation as well as prognosis prediction for elderly patients with colorectal cancer.
authors.affiliation: Department of Surgery, Affiliated Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou 510180, China. czhongt@126.com.
authors.forename: Ying-zhi
authors.initials: YZ
authors.lastname: Chang
authors.forename: Jie
authors.initials: J
authors.lastname: Cao
authors.forename: Wei-min
authors.initials: WM
authors.lastname: Tan
authors.forename: Shi-min
authors.initials: SM
authors.lastname: Luo
authors.forename: Si-min
authors.initials: SM
authors.lastname: Zhuang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D015596:Nutrition Assessment; D011379:Prognosis; D012189:Retrospective Studies