title: Metal nanoparticle-functionalized DNA tweezers: from mechanically programmed nanostructures to switchable fluorescence properties.
abstract: DNA tweezers are modified with two 10-nm sized Au NPs and one 5-nm sized Au NP. Upon treatment of the tweezers with fuel and antifuel nucleic acid strands, the switchable closure and opening of the tweezers proceed, leading to the control of programmed nanostructures of the tethered NPs. The tweezers are further modified with a single 10-nm sized nanoparticle, and a fluorophore unit (Cy3), positioned at different distinct sites of the tweezers. The reversible and cyclic fluorescence quenching or fluorescence enhancement phenomena, upon the dynamic opening/closure of the different tweezers, are demonstrated.
authors.affiliation: The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
authors.forename: Simcha
authors.initials: S
authors.lastname: Shimron
authors.forename: Alessandro
authors.initials: A
authors.lastname: Cecconello
authors.forename: Chun-Hua
authors.initials: CH
authors.lastname: Lu
authors.forename: Itamar
authors.initials: I
authors.lastname: Willner
mesh_terms: D004247:DNA / Q000737:chemistry*; D005453:Fluorescence; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology; D052898:Optical Tweezers
chemical_list: D006046:Gold; D004247:DNA