title: [The effects of oxygen partial pressure changes on the osteometric markers of the bone tissue in rats].
abstract: Our purpose was to investigate the oxygen partial pressure changes on the osteometric and biochemical markers of bone tissue in rats. It was shown that breathing of altered gas mixture did not change the mass, general length, sagittal diameter and density thigh-bones in 12-month Wistar male-rats. The dosed normobaric hypoxia increased the activity of alkaline phosphatase and decreased the activity of tartrate-resistant acid phosphatase. At the same time normobaric hyperoxia with 40 and 90% oxygen conversely decreased the activity of alkaline phosphatase and increased the activity of tartrate-resistant acid phosphatase.
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Berezovs'kyĭ
authors.forename: T M
authors.initials: TM
authors.lastname: Zamors'ka
authors.forename: R V
authors.initials: RV
authors.lastname: Ianko
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D015519:Bone Density / Q000502:physiology; D001861:Bone Regeneration / Q000502:physiology; D050281:Bones of Lower Extremity / Q000033:anatomy & histology* / Q000201:enzymology; D000860:Hypoxia / Q000201:enzymology / Q000503:physiopathology*; D007527:Isoenzymes / Q000378:metabolism; D008297:Male; D010100:Oxygen / Q000378:metabolism*; D010313:Partial Pressure; D051381:Rats; D017208:Rats, Wistar; D000071681:Tartrate-Resistant Acid Phosphatase
chemical_list: D007527:Isoenzymes; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D000071681:Tartrate-Resistant Acid Phosphatase; D010100:Oxygen