title: The clinical utility of the modified checklist for autism in toddlers with high risk 18-48 month old children in Singapore.
abstract: The modified checklist for autism in toddlers (M-CHAT) is a tool developed for 16-30 month old children to screen for autism spectrum disorders (ASD). It is a well-researched tool, but little is known about its utility with Singaporean toddlers and with older children referred for developmental concerns. This study investigated the M-CHAT's performance with 18-30 month old (N = 173) and >30-48 month old (N = 407) developmentally at-risk Singaporean children, when used with three recommended scoring methods i.e., the total, critical and Best7 scoring methods. The results indicate that the critical and Best7 scoring methods detected most true cases of ASD without inflating the false positive rates in toddlers, and that only the total scoring method performed acceptably for the older children.
authors.affiliation: Department of Child Development, KK Women's and Children's Hospital, Women's Tower Level 5, 100 Bukit Timah Road, Singapore, 229899, Singapore, koh.hwan.cui@kkh.com.sg.
authors.forename: Hwan Cui
authors.initials: HC
authors.lastname: Koh
authors.forename: Si Huan
authors.initials: SH
authors.lastname: Lim
authors.forename: Gifford Jiguang
authors.initials: GJ
authors.lastname: Chan
authors.forename: Marisa Bilin
authors.initials: MB
authors.lastname: Lin
authors.forename: Hong Huay
authors.initials: HH
authors.lastname: Lim
authors.forename: Sylvia Henn Tean
authors.initials: SH
authors.lastname: Choo
authors.forename: Iliana
authors.initials: I
authors.lastname: Magiati
mesh_terms: D001321:Autistic Disorder / Q000175:diagnosis / Q000453:epidemiology; D057189:Checklist; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis* / Q000453:epidemiology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008403:Mass Screening / Q000379:methods; D012306:Risk; D012846:Singapore / Q000453:epidemiology; D011795:Surveys and Questionnaires