title: The evolutionary pathway of x chromosome inactivation in mammals.
abstract: X chromosome inactivation is a complex process that occurs in marsupial and eutherian mammals. The process is thought to have arisen during the differentiation of mammalian sex chromosomes to achieve an equal dosage of X chromosome genes in males and females. The differences in the X chromosome inactivation processes in marsupial and eutherian mammals are considered, and the hypotheses on its origin and evolution are discussed in this review.
authors.affiliation: Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Prospekt Lavrentyeva, 10, Novosibirsk, Russia, 630090 ; State Research Institute of Circulation Pathology, Rechkunovskaya Str., 15, Novosibirsk, Russia, 630055 ; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Prospekt Lavrentyeva, 8, Novosibirsk, Russia, 630090.
authors.forename: A I
authors.initials: AI
authors.lastname: Shevchenko
authors.forename: I S
authors.initials: IS
authors.lastname: Zakharova
authors.forename: S M
authors.initials: SM
authors.lastname: Zakian
keywords: X chromosome inactivation; Xist.; mammals