title: Aggregating the message to control the cell cycle.
abstract: Localization of messenger RNAs (mRNAs) enables the precise regulation of protein expression in space and time. In this issue of Developmental Cell, Lee et al. (2013) report that the RNA-binding protein Whi3 spatially constrains a cyclin-encoding mRNA in the cytoplasm of multinucleate cells, thus allowing independent cell-cycle control of individual nuclei.
authors.affiliation: Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany. alberti@mpi-cbg.de
authors.forename: Simon
authors.initials: S
authors.lastname: Alberti
mesh_terms: D016213:Cyclins / Q000235:genetics* / Q000378:metabolism*; D055169:Eremothecium / Q000235:genetics* / Q000378:metabolism*; D015533:Transcriptional Activation / Q000502:physiology*
chemical_list: D016213:Cyclins