title: Hypercholesterolemia as one of the risk factors of intracerebral hemorrhage.
abstract: Stroke is still a major cause of morbidity and mortality throughout the world, although better stratification and treatment modalities are being developed. As compared to ischemic stroke, intracerebral hemorrhage (ICH) possesses many unknown data and lacks guidelines for better prophylaxis. In this study, we aimed to investigate patients with ICH hospitalized in our neurology department within 5 years in terms of risk stratification. A total of 4,449 patients were hospitalized; 1,378 of patients (31%) were diagnosed as having cerebrovascular disease and of these 165 patients (3.7%) had ICH. The risk factors of patients with ICH were investigated and compared with age- and gender matched 75 healthy subjects. We observed that hypercholesterolemia (p = 0.002) was one of the most common risk factors in patients with ICH as compared to controls, together with hypertension (p = 0.010). On the other hand, hypolipidemia (LDL-cholesterol level < 50 mg/dl) was not present in any of the patients. As our purpose as neurologists is to reduce the occurrence and fatal outcome of cerebrovascular events, we aimed to emphasize the importance of risk factors to be well defined, for which every effort should be exhibited for both primary and secondary prevention.
authors.affiliation: Department of Neurology, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: Melda
authors.initials: M
authors.lastname: Bozluolcay
authors.forename: Mecbure
authors.initials: M
authors.lastname: Nalbantoglu
authors.forename: R Gokcen
authors.initials: RG
authors.lastname: Gozubatik-Celik
authors.forename: Gulcin
authors.initials: G
authors.lastname: Benbir
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Akalin
authors.forename: Gokhan
authors.initials: G
authors.lastname: Erkol
mesh_terms: D002543:Cerebral Hemorrhage / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors