title: Occupational exposure and thoracic malignancies, is there a relationship?
abstract: OBJECTIVE
  The aim of this study was to evaluate the effect of occupational exposure in the occurrence of lung cancer.
  
  
  METHODS
  Three-hundred lung cancer cases diagnosed between September 1, 1999, and September 31, 2007, and 300 healthy controls were enrolled in this case-control study. Life-long occupational history, gender, age, exposure to asbestos, comorbidities, and smoking status were collected.
  
  
  RESULTS
  The mean age of the 300 lung cancer cases was 60.3 ± 9.9 year (91.7% male and 8.3% female), and the mean age of healthy control group was 60.4 ± 10.5 year (95.0% male and 5.0% female). The most frequent histological types were squamous (172, 57.3%), adeno (69, 23.1%), and small cell (37, 12.3%). There was an increased risk of lung cancer occurrence among agriculture workers (OR=1.89, 95% Cl=1.17-2.98) (p=0.009). Inorganic dust exposure (OR=1.81, 95% Cl=1.0-3.25) (p=0.049) and organic dust exposure (OR=1.89, 95% Cl=1.0-3.59) (p=0.05) were found to be related with high frequency of having lung cancer.
  
  
  CONCLUSIONS
  Workers who had occupational exposure to organic and inorganic dust, especially in the agricultural field, had higher risk of lung cancer occurrence when compared with office workers.
authors.affiliation: Department of Pulmonary Medicine, Pamukkale University Medical Faculty.
authors.forename: Sevin
authors.initials: S
authors.lastname: Baser
authors.forename: Ozlem
authors.initials: O
authors.lastname: Duzce
authors.forename: Fatma
authors.initials: F
authors.lastname: Evyapan
authors.forename: Beyza
authors.initials: B
authors.lastname: Akdag
authors.forename: Sibel
authors.initials: S
authors.lastname: Ozkurt
authors.forename: Goksel
authors.initials: G
authors.lastname: Kiter
mesh_terms: D000368:Aged; D000383:Agriculture; D016022:Case-Control Studies; D016001:Confidence Intervals; D004391:Dust / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis; D016017:Odds Ratio; D011795:Surveys and Questionnaires; D013899:Thoracic Neoplasms / Q000453:epidemiology / Q000209:etiology*; D014421:Turkey / Q000453:epidemiology
chemical_list: D004391:Dust