title: [Non-traumatic splenic rupture during the chemotherapy and successful management by emergency splenectomy in a patient with blastic plasmacytoid dendritic cell neoplasm].
abstract: Spontaneous rupture of the spleen is a rare but important complication in hematological malignancies. Without splenectomy, the mortality rate of these patients is nearly 100%. We present a blastic plasmacytoid dendritic cell neoplasm case with this complication. Nine days after initiation of chemotherapy, the patient had increased epigastric pain and a drop in hemoglobin. CT scan showed an enlarged spleen surrounded by hemorrhage. Spontaneous rupture of the spleen was diagnosed. Although the patient had severe bone marrow suppression due to chemotherapy, emergency splenectomy was performed and the patient recovered.
authors.affiliation: Department of Hematology/Oncology, University of Yamanashi.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Kawashima
authors.forename: Yuki
authors.initials: Y
authors.lastname: Sueki
authors.forename: Takeo
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hamanaka
authors.forename: Yumi
authors.initials: Y
authors.lastname: Nozaki
authors.forename: Kei
authors.initials: K
authors.lastname: Nakajima
authors.forename: Toru
authors.initials: T
authors.lastname: Mitsumori
authors.forename: Keita
authors.initials: K
authors.lastname: Kirito
mesh_terms: D000328:Adult; D003713:Dendritic Cells / Q000473:pathology*; D019337:Hematologic Neoplasms / Q000188:drug therapy*; D006801:Humans; D008297:Male; D011859:Radiography; D012422:Rupture, Spontaneous / Q000601:surgery*; D013156:Splenectomy / Q000379:methods; D013161:Splenic Rupture / Q000000981:diagnostic imaging / Q000601:surgery*; D016896:Treatment Outcome