title: Phosphine-catalyzed Rauhut-Currier domino reaction: a facile strategy for the construction of carbocyclic spirooxindoles skeletons.
abstract: Push-over: A novel domino reaction of activated conjugated dienes and methyleneindolinones incorporates a phosphine-catalyzed intermolecular Rauhut-Currier to form two C-C bonds and a quaternary carbon center. This method can be used to synthesize spirocyclopenteneoxindoles skeletons, which are potential building blocks for biologically active compounds.
authors.affiliation: State Key Laboratory and Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China.
authors.forename: Chongchong
authors.initials: C
authors.lastname: Hu
authors.forename: Qinglong
authors.initials: Q
authors.lastname: Zhang
authors.forename: You
authors.initials: Y
authors.lastname: Huang
mesh_terms: D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D000078183:Oxindoles; D010720:Phosphines / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D000078183:Oxindoles; D010720:Phosphines; D013141:Spiro Compounds; C022960:2-oxindole; D002244:Carbon; C044646:phosphine
keywords: catalysis; conjugation; domino reactions; phosphines; spiro compounds