title: Cytomegalovirus polyradiculopathy of late onset in a young renal transplant recipient.
abstract: Although cytomegalovirus (CMV) disease in CMV IgM/IgG-negative renal transplant recipients from CMV-positive donors (D+/R-) can occur after discontinuation of prophylaxis treatment as a flu-like syndrome or tissue invasive disease, involvement of the central nervous system is rare. Here, we report a case of CMV polyradiculopathy 6 months after renal transplantation that presented as a Guillain-Barre like syndrome and was successfully treated with foscarnet. This case highlights an uncommon aspect of CMV invasive disease which we should keep in mind in CMV (D+/R-) renal transplant recipients.
authors.affiliation: Department of Internal Medicine, University Hospital of Patras, Patras, Greece. dgoumenos@upatras.gr
authors.forename: Marios
authors.initials: M
authors.lastname: Papasotiriou
authors.forename: Evangelos
authors.initials: E
authors.lastname: Papachristou
authors.forename: Markos
authors.initials: M
authors.lastname: Marangos
authors.forename: Maria
authors.initials: M
authors.lastname: Koukoulaki
authors.forename: Eirini
authors.initials: E
authors.lastname: Savvidaki
authors.forename: Pantelitsa
authors.initials: P
authors.lastname: Kalliakmani
authors.forename: Dimitrios S
authors.initials: DS
authors.lastname: Goumenos
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy; D017245:Foscarnet / Q000627:therapeutic use; D015774:Ganciclovir / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D011128:Polyradiculopathy / Q000175:diagnosis / Q000821:virology*; D013997:Time Factors; D000077562:Valganciclovir
chemical_list: D000998:Antiviral Agents; D017245:Foscarnet; D000077562:Valganciclovir; D015774:Ganciclovir