title: Universal tumor-reactive helper peptides from telomerase as new tools for anticancer vaccination.
abstract: Accumulating evidence demonstrates the importance of CD4+T cells in antitumor immune responses. Identifying promiscuous MHC class II-binding peptides derived from relevant tumor-associated antigens that specifically target CD4+helper T cells in vivo represent a powerful approach to fully exploit these cells for anticancer immunotherapy.
authors.affiliation: INSERM; Unité Mixte de Recherche 1098; Besançon, France ; Etablissement Français du Sang de Bourgogne Franche-Comté; UMR1098; Besançon, France ; Université de Franche-Comté; UMR1098; SFR IBCT; Besançon, France.
authors.forename: Magalie
authors.initials: M
authors.lastname: Dosset
authors.forename: Charline
authors.initials: C
authors.lastname: Vauchy
authors.forename: Laurent
authors.initials: L
authors.lastname: Beziaud
authors.forename: Olivier
authors.initials: O
authors.lastname: Adotevi
authors.forename: Yann
authors.initials: Y
authors.lastname: Godet
keywords: CD4 T cell; cancer vaccine; helper peptide; immunotherapy; telomerase