title: Lysine-specific demethylase 1-selective inactivators: protein-targeted drug delivery mechanism.
authors.affiliation: Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 13 Nishitakatsukasa-cho, Taishogun Kita-ku, Kyoto 603-8334, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Ogasawara
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Itoh
authors.forename: Hiroki
authors.initials: H
authors.lastname: Tsumoto
authors.forename: Taeko
authors.initials: T
authors.lastname: Kakizawa
authors.forename: Koshiki
authors.initials: K
authors.lastname: Mino
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Fukuhara
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Nakagawa
authors.forename: Makoto
authors.initials: M
authors.lastname: Hasegawa
authors.forename: Ryuzo
authors.initials: R
authors.lastname: Sasaki
authors.forename: Tamio
authors.initials: T
authors.lastname: Mizukami
authors.forename: Naoki
authors.initials: N
authors.lastname: Miyata
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Suzuki
mesh_terms: D020134:Catalytic Domain; D018360:Crystallography, X-Ray; D016503:Drug Delivery Systems; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005182:Flavin-Adenine Dinucleotide / Q000378:metabolism; D056466:Histone Demethylases / Q000037:antagonists & inhibitors* / Q000737:chemistry; D006801:Humans; D008239:Lysine / Q000737:chemistry* / Q000378:metabolism; D015394:Molecular Structure; D008995:Monoamine Oxidase / Q000737:chemistry / Q000378:metabolism; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D010446:Peptide Fragments / Q000494:pharmacology*; D054852:Small Molecule Libraries; D014191:Tranylcypromine / Q000494:pharmacology*
chemical_list: D004791:Enzyme Inhibitors; D008996:Monoamine Oxidase Inhibitors; D010446:Peptide Fragments; D054852:Small Molecule Libraries; D005182:Flavin-Adenine Dinucleotide; D014191:Tranylcypromine; D056466:Histone Demethylases; D008995:Monoamine Oxidase; C495195:KDM1A protein, human; D008239:Lysine
keywords: biological activity; drug delivery; drug design; kinetics; proteins