title: Measurement of renal function in patients with chronic kidney disease.
abstract: Chronic kidney disease affects millions of people worldwide and is associated with an increased morbidity and mortality as a result of kidney failure and cardiovascular disease. Accurate assessment of kidney function is important in the clinical setting as a screening tool and for monitoring disease progression and guiding prognosis. In clinical research, the development of new methods to measure kidney function accurately is important in the search for new therapeutic targets and the discovery of novel biomarkers to aid early identification of kidney injury. This review considers different methods for measuring kidney function and their contribution to the improvement of detection, monitoring and treatment of chronic kidney disease.
authors.affiliation: National Poisons Information Service Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK.
authors.forename: Euan A
authors.initials: EA
authors.lastname: Sandilands
authors.forename: Neeraj
authors.initials: N
authors.lastname: Dhaun
authors.forename: James W
authors.initials: JW
authors.lastname: Dear
authors.forename: David J
authors.initials: DJ
authors.lastname: Webb
mesh_terms: D015415:Biomarkers / Q000097:blood / Q000652:urine; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D007668:Kidney / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology*; D007677:Kidney Function Tests / Q000379:methods*; D008279:Magnetic Resonance Imaging; D051436:Renal Insufficiency, Chronic / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology / Q000652:urine
chemical_list: D015415:Biomarkers
keywords: chronic kidney disease; glomerular filtration rate; renal dysfunction