title: [Safety and beneficial effects of spinal morphine on the postoperative course of elderly patients undergoing surgical fixation of the femoral neck fracture].
abstract: BACKGROUND
  We performed a retrospective study of the efficacy and safety of spinal anesthesia with 0.1 mg morphine in the postoperative course of elderly patients with femoral neck fracture.
  
  
  METHODS
  Sixty patients with ages averaging 84 years participated in this study. Surgery was performed under spinal anesthesia. Patients were assigned to either a group receiving of 0.1 mg morphine added to isobaric bupivacaine (Group M) or a group receiving of isobaric bupivacaine alone (Group B). The frequency of analgesic use and the occurrence of adverse side effects during the first 48 hours after surgery were compared between the two groups.
  
  
  RESULTS
  In the first 24 hours, the patients in Group M needed significantly less analgesics compared to Group B. The incidence of adverse side effects did not differ significantly between the groups, although nausea had a tendency to increase in Group M. One patient in Group M showed a mild decrease in oxygen saturation.
  
  
  CONCLUSIONS
  The spinal administration of 0.1 mg morphine had beneficial effects and was safe in the postoperative period of elderly patients with femoral neck fracture provided that sufficient observation was given.
authors.affiliation: Department of Anesthesiology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510.
authors.forename: Tatsunori
authors.initials: T
authors.lastname: Watanabe
authors.forename: Takashi
authors.initials: T
authors.lastname: Fujiwara
authors.forename: Takashi
authors.initials: T
authors.lastname: Mochida
authors.forename: Ippei
authors.initials: I
authors.lastname: Watanabe
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Baba
mesh_terms: D000369:Aged, 80 and over; D000700:Analgesics / Q000008:administration & dosage; D000775:Anesthesia, Spinal / Q000009:adverse effects; D002045:Bupivacaine / Q000008:administration & dosage; D005260:Female; D005265:Femoral Neck Fractures / Q000601:surgery*; D006801:Humans; D008297:Male; D009020:Morphine / Q000008:administration & dosage* / Q000009:adverse effects; D010149:Postoperative Pain / Q000517:prevention & control
chemical_list: D000700:Analgesics; D009020:Morphine; D002045:Bupivacaine