title: Value of open horizontal glottectomy in the treatment for T1b glottic cancer with anterior commissure involvement.
abstract: BACKGROUND
  The aim of the study was to evaluate the treatment outcomes in the group of 108 T1b glottic cancer patients with the anterior commissure involvement treated with open horizontal glottectomy and to compare them with transoral laser microsurgery (TLM) or primary radiotherapy (XRT) results from the literature review.
  
  
  METHODS
  Status of surgical margins, local and nodal recurrence, organ preservation and survival rates, functional outcomes were major end points of interest.
  
  
  RESULTS
  Recurrence rate was 16.7% and was correlated with histologically confirmed prelaryngeal node metastases. Salvage laryngectomy was performed in 10 patients, organ preservation rate was 90.7%. Mean survival was 41.9 months, while 5-year overall survival 97.2%.
  
  
  CONCLUSIONS
  Local control and survival rates presented by the authors are comparable or even better than in TLM procedures or XRT outcomes from the literature. Positive prelaryngeal lymph nodes constituted a significant prognostic factor for nodal and local recurrence in the analyzed group.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Poznań University of Medical Sciences, Poland.
authors.forename: Witold
authors.initials: W
authors.lastname: Szyfter
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Leszczyńska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Wierzbicka
authors.forename: Tomasz
authors.initials: T
authors.lastname: Kopeć
authors.forename: Anna
authors.initials: A
authors.lastname: Bartochowska
mesh_terms: D000328:Adult; D000368:Aged; D003679:Deglutition; D005260:Female; D005500:Follow-Up Studies; D005931:Glottis / Q000601:surgery*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D053685:Laser Therapy; D008207:Lymphatic Metastasis; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D037981:Neck Dissection; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D016609:Neoplasms, Second Primary; D059351:Organ Sparing Treatments; D011379:Prognosis; D016879:Salvage Therapy; D014140:Tracheotomy; D014833:Voice Quality
keywords: anterior commissure invasion; early cancer; glottis; partial laryngectomy; surgery