title: [Determination of 15 kinds of pesticides in blood by gas chromatography-mass spectrometry].
abstract: OBJECTIVE
  To develop the method of gas chromatography-mass spectrometry (GC-MS) for simultaneous determination of 15 herbicides in blood.
  
  
  METHODS
  2ml of blood in vitro were sampled, concentrated and extracted with dichloromethane, reconstant with methanol agents of Gulonic acid lactone solution, and detected by GC-MS.
  
  
  RESULTS
  Experimental results show that diazinon, atrazine, prometryn, methyl parathion, butachlor, bifenthrin at 4-80 microg/L, phorate, malathion, 2,4-D butyl ester, chlordane, fenpropathrin at 10-200 microg/L, alpha-endosulfan, beta-endosulfan, cyhalothrin at 20-400 microg/L, dimethoate at 40-800 microg/L, with good linear response. The correlation coefficient (r2) were between 0.998-1.000, respectively. The recovery of all analysts averaged between 56%-128% in blood samples. The detection limits of all compounds between 0.05 and 1.00 microg/L. The lower limit of quantification between 0.20 and 3.001 microg/L.
  
  
  CONCLUSIONS
  The methods is apply to detect the content of analysts in blood samples.
authors.affiliation: Chinese Center for Disease Control and Prevention, National Institute of Occupational Health and Poison Control, Beijing, China. panxf1@chinacdc.cn
authors.forename: Xingfu
authors.initials: X
authors.lastname: Pan
authors.forename: Huifang
authors.initials: H
authors.lastname: Du
authors.forename: Huifang
authors.initials: H
authors.lastname: Yan
mesh_terms: D001280:Atrazine / Q000097:blood; D003976:Diazinon / Q000097:blood; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006801:Humans; D010573:Pesticide Residues / Q000097:blood*; D011400:Prometryne / Q000097:blood
chemical_list: D010573:Pesticide Residues; D011400:Prometryne; D001280:Atrazine; D003976:Diazinon