title: Revealing structural views of biology.
abstract: The first protein structures were determined in the 1950s. In the decades that followed, development of new methods for sample preparation, crystallization, data collection, and structure analysis yielded tens of thousands of biomolecular structures. This short review highlights some of the major technical advances exemplified with selected structures.
authors.affiliation: RCSB Protein Data Bank and Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037.
authors.forename: David S
authors.initials: DS
authors.lastname: Goodsell
authors.forename: Stephen K
authors.initials: SK
authors.lastname: Burley
authors.forename: Helen M
authors.initials: HM
authors.lastname: Berman
mesh_terms: D003460:Crystallization; D011506:Proteins / Q000737:chemistry
chemical_list: D011506:Proteins
keywords: Protein Data Bank; nucleic acid structure; protein structure