title: [Effects of CdTe QDs on chromosome aberration of CHL cells in vitro].
abstract: OBJECTIVE
  To observed the chromosome oberration of CHL cells induced by CdTe QDs.
  
  
  METHODS
  The chromosome oberration test of Chinese hamster lung (CHL) cell was conducted in CdTe QDs at the concentrations of 1.6, 3.2, 6.3, 12.6 and 25.2 microl/ml, under the metabolic (+S9) and non-metabolic (-S9) activation systems.
  
  
  RESULTS
  The chromosome oberration rate of 12.6 and 25.2 microl/ml CdTe QDs groups were significantly higher than the control groups (P<0.01) Under the condition of metabolic activation. Main types of chromosomal aberrations was broken, fragmented and exchange.
  
  
  CONCLUSIONS
  It was suggested that CdTe QDs could induce the effects of chromosome oberration under the metabolic activation systems (+S9).
authors.affiliation: Institute for Ocuupational Health and Poisoning Control, Chinese Center for Disease Control and Prevention, Beijing, China. guangyunxie@163.com
authors.forename: Guangyun
authors.initials: G
authors.lastname: Xie
authors.forename: Quankai
authors.initials: Q
authors.lastname: Wang
authors.forename: Anna
authors.initials: A
authors.lastname: Wang
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.forename: Peili
authors.initials: P
authors.lastname: Huang
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Sun
mesh_terms: D000818:Animals; D019187:Cadmium Compounds / Q000633:toxicity*; D002460:Cell Line; D002869:Chromosome Aberrations / Q000187:drug effects*; D006224:Cricetinae; D003412:Cricetulus; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D008168:Lung / Q000166:cytology* / Q000378:metabolism; D045663:Quantum Dots / Q000633:toxicity*; D013691:Tellurium / Q000633:toxicity*
chemical_list: D019187:Cadmium Compounds; D013691:Tellurium; C028337:cadmium telluride