title: Treatment of medically inoperable non-small-cell lung cancer with stereotactic body radiation therapy versus image-guided tumor ablation: can interventional radiology compete?
abstract: Patients with medically inoperable stage IA non-small-cell lung cancer have treatment options that include image-guided tumor ablation or stereotactic body radiation therapy. Literature to date with both techniques suggests similar overall survival; however, local control rates appear to be higher with SBRT. It is important for interventional radiologists to understand the differences and similarities between these two techniques. Future research is important to determine which patients would benefit from these therapies. This review summarizes the two techniques and available clinical literature, provides relevant commentary, and suggests future directions for research in this area.
authors.affiliation: Department of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI 02903, USA. ddupuy@lifespan.org
authors.forename: Damian E
authors.initials: DE
authors.lastname: Dupuy
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D017115:Catheter Ablation / Q000009:adverse effects / Q000401:mortality; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D018579:Patient Selection; D015641:Radiography, Interventional; D016634:Radiosurgery / Q000009:adverse effects / Q000401:mortality; D012307:Risk Factors; D016896:Treatment Outcome
keywords: ACOSOG; American College of Surgeons Oncology Group; IGTA; NCI; NSCLC; National Cancer Institute; PET; RF; RTOG; Radiation Therapy Oncology Group; SBRT; image-guided tumor ablation; non–small-cell lung cancer; positron emission tomography; radiofrequency; stereotactic body radiation therapy