title: Friction-induced pagetoid dyskeratosis.
abstract: BACKGROUND
  Pagetoid dyskeratosis (PD) is characterized by pale cells within the epidermis resembling those of Paget disease. These cells have been seen as an incidental finding in a variety of benign papules most commonly located in intertriginous areas. The lesion is considered a reactive process in which a small proportion of the normal population of keratinocytes is altered. Among the triggers for this lesion, friction has been suggested; however, a direct cause-and-effect relationship has not yet been reported.
  
  
  RESULTS
  We confirmed the relationship between PD and friction in a biopsy taken from a 19-year-old woman who presented with clinical features indicating exogenously induced bullae and erosions and consented to a biopsy of a lesion immediately after its induction, demonstrating combined features of PD and friction bulla.
authors.affiliation: Department pf Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC.
authors.forename: Faisal
authors.initials: F
authors.lastname: Al-Mohammedi
authors.forename: Gillian C
authors.initials: GC
authors.lastname: de Gannes
authors.forename: Richard I
authors.initials: RI
authors.lastname: Crawford
mesh_terms: D005260:Female; D017276:Friction; D006801:Humans; D015603:Keratinocytes; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology*; D055815:Young Adult