title: [Radiotherapy after testicular-sparing surgery for bilateral or monorchide testicular tumours: an innovative approach].
abstract: Testicular-sparing surgery may avoid definitive testosterone supplementation and preserve fertility in selected cases of men presenting with bilateral testicular tumours or in case of monorchidia. Testicular-sparing surgery may enable the conservation of both endocrine function and spermatogenesis in selected young men in order to preserve natural fatherhood, avoid definitive androgen replacement therapy and probably improve quality of life by reducing psychosexual consequences of anorchia. The tumorectomy must be followed by an external irradiation of the remaining testicle to eradicate testicular intratubular neoplasia revealed in 82% of cases after per-surgery biopsy. This approach concerns some rare indications. Dose level and technical consideration are still debated.
authors.affiliation: Département de Radiothérapie, Institut Bergonié, Centre Régional de Lutte Contre le Cancer, 229 Cours de l'Argonne, 33076 Bordeaux cedex, France. p.sargos@bordeaux.unicancer.fr
authors.forename: P
authors.initials: P
authors.lastname: Sargos
authors.forename: L
authors.initials: L
authors.lastname: Ferretti
authors.forename: B
authors.initials: B
authors.lastname: Henriques de Figueiredo
authors.forename: F
authors.initials: F
authors.lastname: Cornelis
authors.forename: S
authors.initials: S
authors.lastname: Belhomme
authors.forename: B
authors.initials: B
authors.lastname: Dallaudière
authors.forename: P
authors.initials: P
authors.lastname: Richaud
mesh_terms: D002278:Carcinoma in Situ / Q000188:drug therapy / Q000532:radiotherapy; D017024:Chemotherapy, Adjuvant; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data; D003131:Combined Modality Therapy; D020249:Hormone Replacement Therapy / Q000523:psychology; D006801:Humans; D007248:Infertility, Male / Q000517:prevention & control / Q000523:psychology; D008297:Male; D015337:Multicenter Studies as Topic / Q000706:statistics & numerical data; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy / Q000523:psychology / Q000532:radiotherapy* / Q000601:surgery; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy / Q000523:psychology / Q000532:radiotherapy / Q000601:surgery; D009919:Orchiectomy / Q000009:adverse effects / Q000379:methods / Q000523:psychology; D059351:Organ Sparing Treatments; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant / Q000379:methods*; D011882:Radiotherapy, High-Energy / Q000009:adverse effects / Q000379:methods*; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data; D013315:Stress, Psychological / Q000209:etiology / Q000517:prevention & control; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000523:psychology / Q000532:radiotherapy* / Q000601:surgery; D013737:Testis / Q000473:pathology / Q000528:radiation effects / Q000601:surgery; D013739:Testosterone / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D013739:Testosterone
keywords: Bilateral testicular neoplasms; Conservative surgery; Germ cell tumour; Néoplasie testiculaire intraépithéliale; Radiotherapy; Radiothérapie; Testis; Testosterone; Testostérone; Tumeurs bilatérales testiculaires