title: Detectability of newborn chirp-evoked ABR in the frequency domain at different stimulus rates.
abstract: OBJECTIVE
  The present paper reports the results of a study on a group of newborns whose chirp-evoked auditory brainstem responses (ABR) were recorded at different repetition rates. The study was aimed at finding an optimum repetition rate for the chirp stimulus that facilitates a short response detection time in the frequency domain.
  
  
  METHODS
  Chirp-evoked ABR were recorded at six different stimulation rates between 20/s and 100/s. The stimulation level was 35 dB nHL. The mean harmonic related SNR was calculated, and the response detection time and rate were assessed using a detection algorithm.
  
  
  METHODS
  A group of 80 sleeping and 27 awake newborns with normal hearing were included.
  
  
  RESULTS
  The highest mean harmonic-related SNR in both groups was found at 60/s. The signal-to-noise ratio (SNR) was significantly smaller for the awake newborns. A significantly shorter detection time can be achieved for both newborn groups at 60/s compared to the other rates tested. Response detection in the group of awake newborns profited more from the change to 60/s compared to the sleeping newborns.
  
  
  CONCLUSIONS
  It can be expected that with this optimized stimulus paradigm a shorter test time and a higher specificity of the hearing screening can be reached.
authors.affiliation: * Comprehensive Hearing Center (CHC), Department of Otorhinolaryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, Julius Maximilian-University Hospitals , Würzburg , Germany.
authors.forename: Mario
authors.initials: M
authors.lastname: Cebulla
authors.forename: Ekkehard
authors.initials: E
authors.lastname: Stürzebecher
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods*; D001306:Auditory Pathways / Q000502:physiology*; D004569:Electroencephalography; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006320:Hearing Tests; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D015997:Neonatal Screening / Q000379:methods*; D011237:Predictive Value of Tests; D059629:Signal-To-Noise Ratio; D012890:Sleep; D013997:Time Factors; D014851:Wakefulness