title: Leimyosarcoma of the buccal mucosa and review of literature.
abstract: Leiomyosarcoma (LMS) is an uncommon malignant spindle cell tumor of the head and neck region. The occurrence is particularly rare in the buccal mucosa of the oral cavity. It is a rapidly growing tumor with aggressive behavior and poor prognosis.
  
  
  METHODS
  This article presents a rare case of primary leimyosarcoma of the buccal mucosa in a 35 year old female and retrospective analysis of primary oral LMS published in the English literature since past 20 years is done. Diagnosis was confirmed by immunohistochemistry profile showing positivity for vimentin, smooth muscle actin (SMA), high proliferative index displayed by Ki-67, focal positivity for pan-CK and negativity for S-100.
  
  
  CONCLUSIONS
  Based on the presence of malignant spindle cells showing positivity for vimentin and SMA, a diagnosis of leiomyosarcoma was made.
authors.affiliation: Department of Oral and Maxillofacial Pathology, Sinhgad Dental College and Hospital, Maharashtra, India.
authors.forename: Deepak Kumar J
authors.initials: DK
authors.lastname: Nagpal
authors.forename: Prashant R
authors.initials: PR
authors.lastname: Prabhu
authors.forename: Amisha
authors.initials: A
authors.lastname: Shah
authors.forename: Sangeeta
authors.initials: S
authors.lastname: Palaskar
keywords: Ki-67; leiomyosarcoma; smooth muscle actin; spindle cell