title: [Proteomics as a fundamental tool for subclinical screening, tests verification and assessment of applied therapy].
abstract: Proteomics is a science which studies proteins of the body, interactions of proteins and their biological functions. Today, it is an essential partner in establishing preclinical diagnosis protocols. In conjunction with other sciences such as genomics and bioinformatics it will be possible to diagnose diseases on the earliest stages before its clinical onset or to gain the dynamics of pathological processes in the body and response to drug therapy. This article discusses general aspects of proteomics as well as special ones on the basis of models of cardiac diseases and cancer.
authors.forename: S V
authors.initials: SV
authors.lastname: Suchkov
authors.forename: D A
authors.initials: DA
authors.lastname: Gnatenko
authors.forename: D S
authors.initials: DS
authors.lastname: Kostiushev
authors.forename: S A
authors.initials: SA
authors.lastname: Krynskiĭ
authors.forename: M A
authors.initials: MA
authors.lastname: Pal'tsev
mesh_terms: D001798:Blood Proteins / Q000032:analysis*; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000378:metabolism; D002319:Cardiovascular System / Q000378:metabolism*; D006801:Humans; D008171:Lung Diseases / Q000378:metabolism*; D008991:Monitoring, Physiologic / Q000379:methods; D009369:Neoplasms / Q000175:diagnosis / Q000378:metabolism*; D040901:Proteomics / Q000379:methods*; D057170:Translational Research, Biomedical / Q000379:methods*
chemical_list: D001798:Blood Proteins