title: Analysis of nutrition mixtures in ITU patients.
abstract: BACKGROUND
  The aim of this study was to analyse the composition of parenteral nutrition (PN) mixtures used in the ITU.
  
  
  METHODS
  Restrospective analysis involved 2124 prescriptions for individual PN bags. They were administered over an 18-month period, to 160 ITU patients with the mean APACHE II score of 26 points (range: 5-61), calculated on admission. The mortality rate was 40%. Nutrition programs were prepared individually following the 2009 ESPEN guidelines. The prescription was modified according to the individual patient's clinical condition. One hundred and sixty prescriptions were analysed on the first day of PN (T1), 139 - on the second day (T2) and 1825 on the third and subsequent days (T3).
  
  
  RESULTS
  The mean energy supplies were: 1381 kcal/day (range: 456-2612) on T1, 1467 kcal/day (range: 524-2860) on T2, and 1654 kcal/day (range: 390-2969) on T3. The mean supplies of amino acids, glucose and lipids were as follows: amino acids 68.3 g/day (range:20-120) on T1; 71.6 g/ day (range:27.5-125) on T2; 88.0 g/day (range:11-196) on T3; glucose 210.25 g/day (range: 120- 400) on T1; 218.34 g/day (range: 65-480) on T2; 278.5 g/day (range: 18-520) on T3; lipids 34.9 g/ day (range: 0-100) on T1; 38.7 g/day (range: 0-100) on T2; 52.66 g/day (range: 0-117) on T3. The percentages of non-protein energy from lipids were: 29.25 (0-73) on T1; 31.58 (range: 0-60) on T2; 33.5 (0-60) on T3. The following statistically significant differences were found: T2-T3- (p<0.05).
  
  
  CONCLUSIONS
  The compositions of nutrition bags prepared for ITU patients were consistent with the ESPEN guidelines. The composition varied on different days of nutrition. The differences in the supply of nutrition components indirectly confirm the need for individual prescriptions for ITU patients.
authors.affiliation: Department of Anaesthesiology and Intensive Therapy, Collegium Medicum, Nicolaus Copernicus University in Bydgoszcz.
authors.forename: Marlena
authors.initials: M
authors.lastname: Jakubczyk
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Kusza
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Kurczewska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Domjan
authors.forename: Monika
authors.initials: M
authors.lastname: Piotrowska
authors.forename: Stanisław
authors.initials: S
authors.lastname: Kłęk
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Szkulmowski
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Wawrzyniak
authors.forename: Stanisław
authors.initials: S
authors.lastname: Dąbrowiecki
authors.forename: Przemysław
authors.initials: P
authors.lastname: Baranowski
authors.forename: Przemysław
authors.initials: P
authors.lastname: Paciorek
mesh_terms: D018806:APACHE; D006801:Humans; D007362:Intensive Care Units; D010288:Parenteral Nutrition / Q000379:methods*; D057947:Parenteral Nutrition Solutions / Q000008:administration & dosage / Q000032:analysis*; D017410:Practice Guidelines as Topic; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D057947:Parenteral Nutrition Solutions