title: The use of a rapid assay to detect the neuraminidase production in oral Porphyromonas spp. isolated from dogs and humans.
abstract: Neuraminidase was produced by 32.1% and 28.5% of Porphyromonas from dogs with and without periodontitis, respectively; and by 31.8% of bacteria from humans. The presence of neuraminidase in Porphyromonas spp. suggests that this enzyme can be involved with the pathogenesis of the periodontal disease, and the use of this assay to detect the neuraminidase production in oral Porphyromonas species is suggested.
authors.affiliation: Anaerobe Laboratory, Department of Microbiology, Biomedical Science Institute, University of São Paulo, São Paulo, SP, Brazil.
authors.forename: Paulo R G R
authors.initials: PR
authors.lastname: de Assis
authors.forename: Viviane
authors.initials: V
authors.lastname: Nakano
authors.forename: Gerusa N A
authors.initials: GN
authors.lastname: Senhorinho
authors.forename: Mario J
authors.initials: MJ
authors.lastname: Avila-Campos
mesh_terms: D000818:Animals; D001431:Bacteriological Techniques / Q000379:methods*; D004285:Dogs; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D006801:Humans; D009439:Neuraminidase / Q000032:analysis* / Q000378:metabolism; D010518:Periodontitis / Q000382:microbiology / Q000662:veterinary; D017861:Porphyromonas / Q000201:enzymology* / Q000302:isolation & purification
chemical_list: D009439:Neuraminidase
keywords: Dogs; Neuraminidase; Oral Porphyromonas spp; Periodontal disease