title: Right of admission reserved, no matter the path.
abstract: Native CRISPR-Cas adaptive immunity systems prevent plasmid conjugation and virus-mediated gene transfer. Zhang et al. have recently reported in Molecular Cell that natural transformation is also limited by a simple endogenous CRISPR system, which would make an optimal candidate tool for functional applications such as genome editing.
authors.affiliation: Departamento de Fisiología, Genética y Microbiología, Universidad de Alicante, San Vicente del Raspeig, Spain. Electronic address: fmojica@ua.es.
authors.forename: Francisco J M
authors.initials: FJ
authors.lastname: Mojica
authors.forename: César
authors.initials: C
authors.lastname: Díez-Villaseñor
mesh_terms: D001419:Bacteria / Q000235:genetics* / Q000378:metabolism; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D064130:CRISPR-Associated Proteins / Q000235:genetics / Q000378:metabolism; D064112:Clustered Regularly Interspaced Short Palindromic Repeats
chemical_list: D001426:Bacterial Proteins; D064130:CRISPR-Associated Proteins