title: Cheek metastasis from a bladder tumor: unusual presentation of an aggressive disease.
abstract: Transitional cell carcinoma (TCC) has been well described for its propensity to metastasize to distant sites. Metastases to the soft tissues of the oral cavity from a bladder cancer are extremely rare. We present the case of a 65-year-old man who presented with history of hematuria for 1 month and was found to have high-grade TCC of the bladder. He developed a cheek lesion after 3 weeks, which was diagnosed as metastatic nodule along with pulmonary metastases from high-grade bladder TCC. The patient received chemotherapy followed by the radiotherapy of the cheek lesion, but he succumbed after 3 months due widespread metastatic disease. We also presented a review of the literature regarding this rare presentation.
authors.affiliation: 1 Department of Urology, King George's Medical University, Lucknow - India.
authors.forename: Neeraj
authors.initials: N
authors.lastname: Kumar Goyal
authors.forename: Apul
authors.initials: A
authors.lastname: Goel
authors.forename: Satya Narayan
authors.initials: SN
authors.lastname: Sankhwar
authors.forename: Swarnendu
authors.initials: S
authors.lastname: Mandal
authors.forename: Atin
authors.initials: A
authors.lastname: Singhai
authors.forename: Shailesh
authors.initials: S
authors.lastname: Singh
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis / Q000556:secondary*; D002610:Cheek / Q000473:pathology*; D005153:Facial Neoplasms / Q000175:diagnosis / Q000556:secondary*; D017809:Fatal Outcome; D006417:Hematuria / Q000209:etiology; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000209:etiology; D008175:Lung Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D009361:Neoplasm Invasiveness; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000473:pathology*