title: Feasibility of T2 -weighted turbo spin echo imaging of the human prostate at 7 tesla.
abstract: OBJECTIVE
  To demonstrate that high quality T2 -weighted (T2w) turbo spin-echo (TSE) imaging of the complete prostate can be achieved routinely and within safety limits at 7 T, using an external transceive body array coil only.
  
  
  METHODS
  Nine healthy volunteers and 12 prostate cancer patients were scanned on a 7 T whole-body system. Preparation consisted of B0 and radiofrequency shimming and localized flip angle calibration. T1 and T2 relaxation times were measured and used to define the T2w-TSE protocol. T2w imaging was performed using a TSE sequence (pulse repetition time/echo time 3000-3640/71 ms) with prolonged excitation and refocusing pulses to reduce specific absorption rate.
  
  
  RESULTS
  High quality T2w TSE imaging was performed in less than 2 min in all subjects. Tumors of patients with gold-standard tumor localization (MR-guided biopsy or prostatectomy) were well visualized on 7 T imaging (n = 3). The number of consecutive slices achievable within a 10-g averaged specific absorption rate limit of 10 W/kg was ≥28 in all subjects, sufficient for full prostate coverage with 3-mm slices in at least one direction.
  
  
  CONCLUSIONS
  High quality T2w TSE prostate imaging can be performed routinely and within specific absorption rate limits at 7 T with an external transceive body array.
authors.affiliation: Department of Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
authors.forename: Marnix C
authors.initials: MC
authors.lastname: Maas
authors.forename: Eline K
authors.initials: EK
authors.lastname: Vos
authors.forename: Miriam W
authors.initials: MW
authors.lastname: Lagemaat
authors.forename: Andreas K
authors.initials: AK
authors.lastname: Bitz
authors.forename: Stephan
authors.initials: S
authors.lastname: Orzada
authors.forename: Thiele
authors.initials: T
authors.lastname: Kobus
authors.forename: Oliver
authors.initials: O
authors.lastname: Kraff
authors.forename: Stefan
authors.initials: S
authors.lastname: Maderwald
authors.forename: Mark E
authors.initials: ME
authors.lastname: Ladd
authors.forename: Tom W J
authors.initials: TW
authors.lastname: Scheenen
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D017352:Echo-Planar Imaging / Q000379:methods*; D005240:Feasibility Studies; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013113:Spin Labels; D055815:Young Adult
chemical_list: D013113:Spin Labels
keywords: 7 Tesla; T2-weighted imaging; prostate; ultra-high field