title: Neopierisoids A and B, two new chlorinated 3,4-seco-grayanane diterpenoids with antifeedant activity from flowers of Pieris japonica.
abstract: Two new chlorinated multiacylated 3,4-seco-grayanane diterpenoids, neopierisoids A and B (1 and 2), were isolated from flowers of the poisonous plant Pieris japonica and were identified from spectroscopic analysis and X-ray diffraction data. Both compounds showed obvious antifeedant activity against Pieris brassicae with an EC50 of 10.07 μg/cm(2) for 1 and 5.33 μg/cm(2) for 2, indications of toxic properties. Chlorinated 3,4-seco-grayanane diterpenoids in P. japonica may play a defensive role against herbivores.
authors.affiliation: The Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650050, P R China.
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Li
authors.forename: Xiao-Nian
authors.initials: XN
authors.lastname: Li
authors.forename: Ling-Huan
authors.initials: LH
authors.lastname: Gao
authors.forename: Hai-Zhou
authors.initials: HZ
authors.lastname: Li
authors.forename: Guo-Xing
authors.initials: GX
authors.lastname: Wu
authors.forename: Rong-Tao
authors.initials: RT
authors.lastname: Li
mesh_terms: D000818:Animals; D002080:Butterflies / Q000187:drug effects / Q000502:physiology; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D029791:Ericaceae / Q000737:chemistry*; D005247:Feeding Behavior / Q000187:drug effects; D035264:Flowers / Q000737:chemistry; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D004224:Diterpenes; D010936:Plant Extracts