title: [Lymph node metastases and disease-free survival in cervical cancer patients].
abstract: OBJECTIVE
  To establish the prognostic significance of lymph node metastases (LNM) in terms of disease-free survival and incidence rate and localization of relapses.
  
  
  METHODS
  296 patients with invasive cervical cancer FIGO staged: IB1-110; IB2-98 and IIB-86 had been operated on between 2002-2011. Patients age ranges from 27 to 84 years, average 48 years. Follow-up period was estimated from the date of registration until September 2011 or until the occurrance of relapse. (2-96, average 45 months). 294 patients were submitted to pelvic lymphadenectomy and paraaortic lymphadenectomy was optional.
  
  
  RESULTS
  We presented the relationships between number of LNM, incidence rate of LNM, macro- and micro- LNM and incidence rate and localization of local and distant relapses.
  
  
  CONCLUSIONS
  Lymph node macrometastases leads to significantly higher incidence rate of relapses outside true pelvis in comparison to lymph node micrometastases.
authors.forename: Y
authors.initials: Y
authors.lastname: Kornovski
authors.forename: E
authors.initials: E
authors.lastname: Ismail
authors.forename: S
authors.initials: S
authors.lastname: Slavchev
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002031:Bulgaria / Q000453:epidemiology; D002584:Cervix Uteri / Q000473:pathology; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D011379:Prognosis; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*