title: Role of tricalcium phosphate implant in bridging the large osteoperiosteal gaps in rabbits.
abstract: Treatment options for large osteoperiosteal defects are limited and that which are available are not ideal. Osteoperiosteal defect were created in ulnae of both forelimbs of rabbits and tricalcium phosphate implant was used to bridge the gap. Amongst the 35 implanted ulnae, one implant got dislodged. Rest of the implants showed good adherence to host bone until the final follow up. Five control rabbit limbs (in which no implants were put) showed persistent bone gap. Histological and Electron microscopic examination revealed bone tissues covering the surface of the implant and bridging the gap. New bone was formed in the pores also. Tricalcium phosphate implants showed new bone formation due to osteoconductive properties. They are biodegradable. It is suggested that tricalcium phosphate implants are viable treatment alternatives in management of large osteoperiosteal defects with minimal to no adverse effects.
authors.affiliation: Department of Orthopaedics, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, India. drscgoel@hotmail.com
authors.forename: Satish Chandra
authors.initials: SC
authors.lastname: Goel
authors.forename: Davinder
authors.initials: D
authors.lastname: Singh
authors.forename: Amit
authors.initials: A
authors.lastname: Rastogi
authors.forename: Vinay
authors.initials: V
authors.lastname: Kumaraswamy
authors.forename: Ashank
authors.initials: A
authors.lastname: Gupta
authors.forename: Nitin
authors.initials: N
authors.lastname: Sharma
mesh_terms: D000818:Animals; D002130:Calcium Phosphates / Q000494:pharmacology*; D010521:Periosteum / Q000473:pathology*; D019736:Prostheses and Implants; D011817:Rabbits
chemical_list: D002130:Calcium Phosphates; C018392:tricalcium phosphate