title: Disease patterns of juvenile dermatomyositis from Western India.
abstract: A retrospective assessment of clinical characteristics, complications/ associations, laboratory investigations, treatment modalities and outcome in an inceptional cohort of 22 (male-13) children with juvenile dermatomyositis (JDM) receiving treatment at Jaslok Hospital, Mumbai during 1997- 2012 was performed . Mean age at diagnosis was 7.52 ± 3.99 years. Typical skin rash and muscle weakness were present in all children. Common complications included cutaneous ulcers (27.27%), dysphagia (22.72%) and calcinosis (18.18%).All patients presented with at least one of the serum muscle enzymes elevated. Absence of mortality and cardio-pulmonary complications and a monocyclic course in 72.7% of our patients are at variance from Western series.
authors.affiliation: Department of Pediatrics, Jaslok Hospital and Research Centre, Dr G Deshmukh Marg, Mumbai, India. Correspondence to: Dr Raju P Khubchandani, 31, Kailas Darshan, Near Kennedy Bridge, Nana Chowk, Mumbai 400 007, India. rajukhubchandani@yahoo.co.in.
authors.forename: Pranav R
authors.initials: PR
authors.lastname: Chickermane
authors.forename: Deepali
authors.initials: D
authors.lastname: Mankad
authors.forename: Raju P
authors.initials: RP
authors.lastname: Khubchandani
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003882:Dermatomyositis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D012189:Retrospective Studies; D013256:Steroids / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D013256:Steroids