title: Relationship between repolarization abnormalities and myocardial edema in atypical Tako-Tsubo syndrome.
abstract: In typical "apical" Tako-Tsubo syndrome (TTS), an association between dynamic T-wave inversion/QTc interval prolongation and myocardial edema as evidenced by cardiac magnetic resonance has been reported. We describe a patient with atypical "mid-ventricular" TTS who showed T-waves inversion/QTc prolongation confined to the lateral leads. Cardiac magnetic resonance revealed transmural myocardial edema with the highest signal intensity in the mid-lateral wall, in accordance with the ECG location of repolarization abnormalities. This finding indicates that the association of dynamic T-wave inversion/QTc interval prolongation with myocardial edema is demonstrable also in atypical variant of TTS and contributes to support the emerging concept of a cause-effect relationship between transient myocardial edema and dynamic repolarization changes.
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Padova, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Zorzi
authors.forename: Martina
authors.initials: M
authors.lastname: Perazzolo Marra
authors.forename: Federico
authors.initials: F
authors.lastname: Migliore
authors.forename: Manuel
authors.initials: M
authors.lastname: De Lazzari
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Tarantini
authors.forename: Sabino
authors.initials: S
authors.lastname: Iliceto
authors.forename: Domenico
authors.initials: D
authors.lastname: Corrado
mesh_terms: D001145:Arrhythmias, Cardiac / Q000175:diagnosis* / Q000209:etiology*; D003937:Diagnosis, Differential; D004489:Edema, Cardiac / Q000175:diagnosis* / Q000209:etiology*; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013223:Statistics as Topic; D054549:Takotsubo Cardiomyopathy / Q000150:complications* / Q000175:diagnosis*