title: Persistent hypoglycemia.
abstract: Hypoglycemia is a common finding in emergency departments. In this article, we review the causes of hypoglycemia in children, the evaluation and management of a child with persistent hypoglycemia, and causes of adrenal insufficiency in children. We report a case of adrenoleukodystrophy, a type of primary adrenal insufficiency, in a 5-year-old boy who presented with altered mental status, seizures, and hypoglycemia.
authors.affiliation: Division of Emergency Medicine, Carman and Ann Adam Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI 48201, USA. docklevasseur@gmail.com
authors.forename: Kelly Anne
authors.initials: KA
authors.lastname: Levasseur
authors.forename: Helene
authors.initials: H
authors.lastname: Tigchelaar
authors.forename: Nirupama
authors.initials: N
authors.lastname: Kannikeswaran
mesh_terms: D000074063:ATP Binding Cassette Transporter, Subfamily D, Member 1; D018528:ATP-Binding Cassette Transporters / Q000172:deficiency / Q000235:genetics; D000312:Adrenal Hyperplasia, Congenital / Q000175:diagnosis; D000309:Adrenal Insufficiency; D000326:Adrenoleukodystrophy / Q000175:diagnosis* / Q000235:genetics; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis; D002675:Child, Preschool; D003244:Consciousness Disorders / Q000209:etiology; D003681:Dehydration / Q000209:etiology / Q000628:therapy; D057210:Delayed Diagnosis; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D003967:Diarrhea / Q000209:etiology; D018450:Disease Progression; D005440:Fluid Therapy; D005759:Gastroenteritis / Q000175:diagnosis; D040181:Genetic Diseases, X-Linked / Q000175:diagnosis; D006801:Humans; D000075262:Hypoadrenocorticism, Familial; D007003:Hypoglycemia / Q000188:drug therapy / Q000209:etiology* / Q000235:genetics; D008297:Male; D012640:Seizures / Q000209:etiology; D014839:Vomiting / Q000209:etiology
chemical_list: C115572:ABCD1 protein, human; D000074063:ATP Binding Cassette Transporter, Subfamily D, Member 1; D018528:ATP-Binding Cassette Transporters