title: Oxidized-low density lipoprotein in gingival crevicular fluid of patients with chronic periodontitis: a possible link to atherogenesis.
abstract: OBJECTIVE
  To investigate a possible link between periodontitis and atherogenesis by examining the levels of anti-oxidized low density lipoprotien (ox LDL) and low density lipoprotien (LDL) in gingival crevicular fluid (GCF) and serum of healthy subjects and chronic periodontitis patients.
  
  
  METHODS
  Sixty male subjects (35-55 years) were grouped into 30 healthy individuals and 30 subjects with chronic periodontitis. Serum and GCF samples were obtained from each subject and were assessed for anti-ox LDL and LDL levels.
  
  
  RESULTS
  A significant difference (p < 0.001) was found between the anti-ox-LDL levels in GCF of healthy vs chronic periodontitis groups. Also the ratio of GCF anti-ox LDL to GCF LDL was significantly higher (p < 0.001) in chronic periodontitis patients as compared to the healthy group.
  
  
  CONCLUSIONS
  A significant rise in ox LDL level in otherwise systemically healthy chronic periodontitis patients may put these subjects at an increased risk of developing atherosclerosis.
authors.affiliation: Department of Periodontics, Bapuji Dental College and Hospital , Davangere, Karnataka , India.
authors.forename: Rucha
authors.initials: R
authors.lastname: Shah
authors.forename: Raison
authors.initials: R
authors.lastname: Thomas
authors.forename: Dhoom Singh
authors.initials: DS
authors.lastname: Mehta
mesh_terms: D002908:Chronic Disease; D005883:Gingival Crevicular Fluid / Q000378:metabolism*; D006801:Humans; D008077:Lipoproteins, LDL / Q000378:metabolism*; D010518:Periodontitis / Q000378:metabolism*
chemical_list: D008077:Lipoproteins, LDL; C099252:oxidized low density lipoprotein