title: Candida pneumonia in a term infant after prolonged use of inhaled corticosteroids for bronchopulmonary dysplasia (BPD).
abstract: Candida spp. frequently cause invasive fungal disease in neonates, and many organs or apparatus can be involved through bloodstream dissemination. Though Candida spp. can heavily colonize the upper and lower respiratory tract, an end-organ localization to the lung is not frequent and acquisition via descending/respiratory route is a questioned entity. Here we report the case of a young infant affected by bronchopulmonary dysplasia (BPD) and treated with inhaled steroids who developed Candida pneumonia likely acquired through descending route.
authors.affiliation: Department of Paediatrics and Neonatology, Silvio Orlandi Hospital, Bussolengo, Verona, Italy. eleonora.buzzi@alice.it
authors.forename: Eleonora
authors.initials: E
authors.lastname: Buzzi
authors.forename: Paolo
authors.initials: P
authors.lastname: Manzoni
authors.forename: Elio
authors.initials: E
authors.lastname: Castagnola
authors.forename: Daniel K
authors.initials: DK
authors.lastname: Benjamin
authors.forename: Renzo
authors.initials: R
authors.lastname: Beghini
authors.forename: Alberto
authors.initials: A
authors.lastname: Dall'agnola
mesh_terms: D000280:Administration, Inhalation; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001997:Bronchopulmonary Dysplasia / Q000150:complications* / Q000188:drug therapy; D002177:Candidiasis / Q000150:complications* / Q000276:immunology; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019570:Inhalation Exposure; D008168:Lung; D008172:Lung Diseases, Fungal / Q000276:immunology / Q000382:microbiology* / Q000628:therapy; D008297:Male; D010102:Oxygen Inhalation Therapy; D012131:Respiratory Insufficiency / Q000276:immunology / Q000382:microbiology / Q000628:therapy; D047929:Term Birth; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D005938:Glucocorticoids