title: Morbidity of central compartment dissection for differentiated thyroid carcinoma of the follicular epithelium.
abstract: OBJECTIVE
  To study the morbidity of central compartment dissection in differentiated thyroid carcinoma of the follicular epithelium.
  
  
  METHODS
  A retrospective study of 83 patients (61 patients operated by total thyroidectomy and 22 patients operated by total thyroidectomy and central dissection) was performed. Postoperative serum calcium and laryngeal mobility were studied and statistically compared (Chi(2) test, Fisher's exact test).
  
  
  RESULTS
  No significant difference was observed between the two groups in terms of the incidence of recurrent laryngeal nerve paralysis or permanent hypoparathyroidism. In contrast, transient hypoparathyroidism was more frequent among patients undergoing thyroidectomy associated with central dissection (P=0.02).
  
  
  CONCLUSIONS
  Central compartment dissection associated with total thyroidectomy does not increase the risk of recurrent laryngeal nerve paralysis or permanent hypoparathyroidism, but is responsible for an increased rate of transient hypoparathyroidism.
authors.affiliation: Service d'ORL et chirurgie cervicofaciale, centre hospitalier Nord, place Victor-Pauchet, 80054 Amiens cedex, France. Electronic address: boutepic@hotmail.com.
authors.forename: P
authors.initials: P
authors.lastname: Boute
authors.forename: J
authors.initials: J
authors.lastname: Merlin
authors.forename: A
authors.initials: A
authors.lastname: Biet
authors.forename: P
authors.initials: P
authors.lastname: Cuvelier
authors.forename: V
authors.initials: V
authors.lastname: Strunski
authors.forename: C
authors.initials: C
authors.lastname: Page
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000097:blood / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D002118:Calcium / Q000097:blood; D002291:Carcinoma, Papillary / Q000097:blood / Q000473:pathology / Q000601:surgery*; D004210:Dissection / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007011:Hypoparathyroidism / Q000209:etiology*; D007828:Laryngoscopy; D008197:Lymph Node Excision / Q000379:methods; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000097:blood / Q000209:etiology*; D012189:Retrospective Studies; D012306:Risk; D013964:Thyroid Neoplasms / Q000473:pathology / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods*; D014826:Vocal Cord Paralysis / Q000209:etiology*
chemical_list: D002118:Calcium
keywords: Central compartment dissection; Hypoparathyroidism; Lymph node metastasis; Recurrent laryngeal nerve paralysis; Thyroid carcinoma