title: Oral hyperpigmented lesions--a case study.
abstract: An overweight woman, aged 58 years, presented for follow up of hypertension, diabetes and dyslipidaemia. She was noted to have hyperpigmented brown macules on the inner surface of the lower lip and buccal mucosa (Figure 1). She stated that she had first noticed these lesions when aged in her 40s. Her mother died at age 58 years from gastric cancer with extensive metastases, and her brother died at age 45 years from colon cancer with spread to the liver and lungs.
authors.affiliation: Department of Family Medicine, International Medical University, Seremban, Negri Sembilan, Malaysia. kwaskim2@yahoo.co.uk
authors.forename: Siew Kim
authors.initials: SK
authors.lastname: Kwa
authors.forename: Esha Das
authors.initials: ED
authors.lastname: Gupta
mesh_terms: D000091162:AMP-Activated Protein Kinase Kinases; D003937:Diagnosis, Differential; D005260:Female; D005817:Genetic Counseling; D005820:Genetic Testing; D006801:Humans; D017495:Hyperpigmentation / Q000175:diagnosis* / Q000235:genetics; D008875:Middle Aged; D009059:Mouth Diseases / Q000175:diagnosis* / Q000235:genetics; D009061:Mouth Mucosa / Q000473:pathology*; D010580:Peutz-Jeghers Syndrome / Q000175:diagnosis* / Q000235:genetics; D017346:Protein Serine-Threonine Kinases / Q000235:genetics
chemical_list: D017346:Protein Serine-Threonine Kinases; C109790:STK11 protein, human; D000091162:AMP-Activated Protein Kinase Kinases