title: Quality of life in patients with multiple sclerosis.
abstract: Multiple sclerosis is a chronic, immune-mediated disease of the central nervous system that typically strikes young adults. It is often associated with a wide range of functional deficits and progressive disability. Common symptoms of multiple sclerosis include vision problems, spasticity, weakness, ataxia, bladder and bowel dysfunctions, fatigue, pain syndromes, tremors, vertigo, cognitive impairment, and mood disorders. Multiple sclerosis has a major negative impact on patient health-related quality of life (HRQoL). Quality of life (QoL) is a multidimensional construct composed of functional, physical, emotional, social and spiritual well-being. Researches have reported that individuals with multiple sclerosis have lower QoL than non-diseased and diseased populations. The inclusion of HRQoL questionnaires in the patient follow-up is a relevant issue to optimize treatment, facilitate treatment decisions and improve adherence, as well as to reduce the inconveniences derived from medication such as side effects.
authors.affiliation: University Department of Neurology, Referral Center for Neurovascular Disorders of the Ministry of Health and Social Welfare of the Republic of Croatia, Sestre milosrdnice University Hospital Center, Zagreb, Croatia. vanjakes@net.hr
authors.forename: Vanja Basić
authors.initials: VB
authors.lastname: Kes
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Cengić
authors.forename: Marijan
authors.initials: M
authors.lastname: Cesarik
authors.forename: Ana Jadrijević
authors.initials: AJ
authors.lastname: Tomas
authors.forename: Iris
authors.initials: I
authors.lastname: Zavoreo
authors.forename: Lucija Zadro
authors.initials: LZ
authors.lastname: Matovina
authors.forename: Lejla
authors.initials: L
authors.lastname: Corić
authors.forename: Sara
authors.initials: S
authors.lastname: Drnasin
authors.forename: Vida
authors.initials: V
authors.lastname: Demarin
mesh_terms: D001259:Ataxia / Q000209:etiology; D059350:Chronic Pain / Q000209:etiology; D003072:Cognition Disorders / Q000209:etiology; D003863:Depression / Q000209:etiology; D004185:Disability Evaluation; D018450:Disease Progression; D005221:Fatigue / Q000209:etiology; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000209:etiology; D019964:Mood Disorders / Q000209:etiology; D009103:Multiple Sclerosis / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D009128:Muscle Spasticity / Q000209:etiology; D018908:Muscle Weakness / Q000209:etiology; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014202:Tremor / Q000209:etiology; D001750:Urinary Bladder, Neurogenic / Q000209:etiology; D014717:Vertigo / Q000209:etiology; D014786:Vision Disorders / Q000209:etiology