title: Design and evaluation of a miniature probe integrating diffuse optical tomography and electroencephalographic source localization.
abstract: We present a dual-modality three-dimensional imaging approach that integrates diffuse optical tomography (DOT) and electroencephalographic source localization (ESL). This dual-modal DOT/ESL approach is evaluated using solid tissue-like phantoms where targets having both optical and electrical contrasts relative to the background phantom are included. The results obtained from extensive phantom experiments show that this dual-modal approach is suitable for imaging seizure focus in the study of epilepsy.
authors.affiliation: Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611, USA.
authors.forename: Hao
authors.initials: H
authors.lastname: Yang
authors.forename: Huabei
authors.initials: H
authors.lastname: Jiang
mesh_terms: D003199:Computer Systems; D004569:Electroencephalography / Q000295:instrumentation* / Q000379:methods; D004827:Epilepsy / Q000175:diagnosis / Q000503:physiopathology*; D004867:Equipment Design; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional; D008904:Miniaturization; D055095:Optics and Photonics / Q000379:methods; D019047:Phantoms, Imaging; D012640:Seizures / Q000175:diagnosis / Q000503:physiopathology*; D019265:Spectroscopy, Near-Infrared / Q000379:methods; D041622:Tomography, Optical / Q000295:instrumentation* / Q000379:methods