title: Effects of topical sprays on allergy-induced nasal obstruction in children.
abstract: OBJECTIVE
  This study aims to evaluate the efficacy of mometasone furoate nasal spray, intranasal azelastine, and isotonic sea water nasal spray in the management of allergy-induced nasal obstruction.
  
  
  METHODS
  Between October 2007 and August 2008 60 patients (37 males, 23 females; mean age 9.8±2.6 years; range 7 to 16 years) with a history of allergic rhinitis were included in the study. Laboratory assays including the skin prick test, nasal smear, phadiatop, total immunoglobulin E (IgE), and complete blood count test were performed. The patients were classified into three groups including 20 in each, according to the topical treatment administered. Patients in group 1 received azelastine, group 2 received mometasone furoate nasal spray, and group 3 received isotonic sea water nasal spray. Nasal passage volume was calculated using an acoustic rhinometry device.
  
  
  RESULTS
  Azelastine and mometasone furoate decreased nasal congestion and increased nasal cavity volume more effectively, compared to isotonic sea water nasal spray.
  
  
  CONCLUSIONS
  Mometasone furoate and azelastine which decrease nasal congestion and increase nasal volume are effective in the management of allergic rhinitis in children.
authors.affiliation: Department of Otolaryngology, Kayseri Training and Research Hospital, 38010 Kayseri, Turkey. drmyasar@hotmail.com
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yaşar
authors.forename: Ismail Önder
authors.initials: IÖ
authors.lastname: Uysal
authors.forename: Emine Elif
authors.initials: EE
authors.lastname: Altuntaş
authors.forename: Ömer
authors.initials: Ö
authors.lastname: Cevit
authors.forename: Suphi
authors.initials: S
authors.lastname: Müderris
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D018926:Anti-Allergic Agents / Q000008:administration & dosage*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D000068656:Mometasone Furoate; D009296:Nasal Cavity / Q000473:pathology; D059085:Nasal Sprays; D010793:Phthalazines / Q000008:administration & dosage*; D011244:Pregnadienediols / Q000008:administration & dosage*; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy* / Q000473:pathology; D012623:Seawater; D012882:Skin Tests; D016896:Treatment Outcome
chemical_list: D018926:Anti-Allergic Agents; D059085:Nasal Sprays; D010793:Phthalazines; D011244:Pregnadienediols; D000068656:Mometasone Furoate; C020976:azelastine