title: Antibacterial activities of selected edible plants extracts against multidrug-resistant Gram-negative bacteria.
abstract: BACKGROUND
  In response to the propagation of bacteria resistant to many antibiotics also called multi-drug resistant (MDR) bacteria, the discovery of new and more efficient antibacterial agents is primordial. The present study was aimed at evaluating the antibacterial activities of seven Cameroonian dietary plants (Adansonia digitata, Aframomum alboviolaceum, Aframomum polyanthum, Anonidium. mannii, Hibiscus sabdarifa, Ocimum gratissimum and Tamarindus indica).
  
  
  METHODS
  The phytochemical screening of the studied extracts was performed using described methods whilst the liquid broth micro dilution was used for all antimicrobial assays against 27 Gram-negative bacteria.
  
  
  RESULTS
  The results of the phytochemical tests indicate that all tested extracts contained phenols and triterpenes, other classes of chemicals being selectively present. The studied extracts displayed various degrees of antibacterial activities. The extracts of A. digitata, H. sabdarifa, A. polyanthum, A. alboviolaceum and O. gratissimum showed the best spectra of activity, their inhibitory effects being recorded against 81.48%, 66.66%, 62.96%, 55.55%, and 55.55% of the 27 tested bacteria respectively. The extract of A. polyanthum was very active against E. aerogenes EA294 with the lowest recorded minimal inhibitory concentration (MIC) of 32 μg/ml.
  
  
  CONCLUSIONS
  The results of the present work provide useful baseline information for the potential use of the studied edible plants in the fight against both sensitive and MDR phenotypes.
authors.forename: Doriane E
authors.initials: DE
authors.lastname: Djeussi
authors.forename: Jaurès A K
authors.initials: JA
authors.lastname: Noumedem
authors.forename: Jackson A
authors.initials: JA
authors.lastname: Seukep
authors.forename: Aimé G
authors.initials: AG
authors.lastname: Fankam
authors.forename: Igor K
authors.initials: IK
authors.lastname: Voukeng
authors.forename: Simplice B
authors.initials: SB
authors.lastname: Tankeo
authors.forename: Antoine H L
authors.initials: AH
authors.lastname: Nkuete
authors.forename: Victor
authors.initials: V
authors.lastname: Kuete
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002163:Cameroon; D004032:Diet; D018432:Drug Resistance, Multiple / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006801:Humans; D019684:Magnoliopsida; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D010945:Plants, Edible
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts