title: lncRNome: a comprehensive knowledgebase of human long noncoding RNAs.
abstract: The advent of high-throughput genome scale technologies has enabled us to unravel a large amount of the previously unknown transcriptionally active regions of the genome. Recent genome-wide studies have provided annotations of a large repertoire of various classes of noncoding transcripts. Long noncoding RNAs (lncRNAs) form a major proportion of these novel annotated noncoding transcripts, and presently known to be involved in a number of functionally distinct biological processes. Over 18,000 transcripts are presently annotated as lncRNA, and encompass previously annotated classes of noncoding transcripts including large intergenic noncoding RNA, antisense RNA and processed pseudogenes. There is a significant gap in the resources providing a stable annotation, cross-referencing and biologically relevant information. lncRNome has been envisioned with the aim of filling this gap by integrating annotations on a wide variety of biologically significant information into a comprehensive knowledgebase. To the best of our knowledge, lncRNome is one of the largest and most comprehensive resources for lncRNAs. Database URL: http://genome.igib.res.in/lncRNome.
authors.affiliation: GN Ramachandran Knowledge Center for Genome Informatics, CSIR Institute of Genomics and Integrative Biology, Mall Road, Delhi 110007, India.
authors.forename: Deeksha
authors.initials: D
authors.lastname: Bhartiya
authors.forename: Koustav
authors.initials: K
authors.lastname: Pal
authors.forename: Sourav
authors.initials: S
authors.lastname: Ghosh
authors.forename: Shruti
authors.initials: S
authors.lastname: Kapoor
authors.forename: Saakshi
authors.initials: S
authors.lastname: Jalali
authors.forename: Bharat
authors.initials: B
authors.lastname: Panwar
authors.forename: Sakshi
authors.initials: S
authors.lastname: Jain
authors.forename: Satish
authors.initials: S
authors.lastname: Sati
authors.forename: Shantanu
authors.initials: S
authors.lastname: Sengupta
authors.forename: Chetana
authors.initials: C
authors.lastname: Sachidanandan
authors.forename: Gajendra Pal Singh
authors.initials: GP
authors.lastname: Raghava
authors.forename: Sridhar
authors.initials: S
authors.lastname: Sivasubbu
authors.forename: Vinod
authors.initials: V
authors.lastname: Scaria
mesh_terms: D001483:Base Sequence; D017124:Conserved Sequence / Q000235:genetics; D030561:Databases, Nucleic Acid; D044127:Epigenesis, Genetic; D056426:Genetic Loci / Q000235:genetics; D014644:Genetic Variation; D015894:Genome, Human / Q000235:genetics; D006801:Humans; D051188:Knowledge Bases; D058977:Molecular Sequence Annotation; D059372:Nucleotide Motifs / Q000235:genetics; D010455:Peptides / Q000235:genetics / Q000378:metabolism; D011485:Protein Binding / Q000235:genetics; D012323:RNA Processing, Post-Transcriptional / Q000235:genetics; D062085:RNA, Long Noncoding / Q000235:genetics* / Q000378:metabolism
chemical_list: D010455:Peptides; D062085:RNA, Long Noncoding