title: Carcinosarcoma of the biliary system in a cat.
abstract: A 12-year-old, mixed-breed domestic cat was diagnosed with a multicystic hepatic mass via ultrasonographic examination and computer tomography scan. The tumor associated with the left medial liver lobe, and connected by a thin stalk to the hilar region, was surgically removed. The mass was firm, encapsulated, mottled white to red black, multinodular, and cystic. Histologic diagnosis was carcinosarcoma supported by positive immunohistochemistry for cytokeratins and vimentin of atypical neoplastic cell populations. On the basis of morphology, the origin was considered to be in the biliary tract. Biliary carcinosarcoma is a rare neoplasm that occurs in people. The epidemiology and risk factors have not yet been determined, and the prognosis is poor except for cases in which curative resection is performed.
authors.affiliation: 1Laura Cavicchioli, Department of Comparative Biomedicine and Food Sciences, University of Padova, Viale dell'Università 16, 35020 Legnaro (PD), Italy. laura.cavicchioli@unipd.it.
authors.forename: Laura
authors.initials: L
authors.lastname: Cavicchioli
authors.forename: Silvia
authors.initials: S
authors.lastname: Ferro
authors.forename: Carolina
authors.initials: C
authors.lastname: Callegari
authors.forename: Edoardo
authors.initials: E
authors.lastname: Auriemma
authors.forename: Eric
authors.initials: E
authors.lastname: Zini
authors.forename: Valentina
authors.initials: V
authors.lastname: Zappulli
mesh_terms: D000818:Animals; D001659:Biliary Tract / Q000000981:diagnostic imaging / Q000473:pathology*; D002296:Carcinosarcoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D002371:Cat Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D002415:Cats; D007150:Immunohistochemistry / Q000662:veterinary; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000662:veterinary*; D008297:Male; D014463:Ultrasonography
keywords: Biliary system; carcinosarcoma; cats; cytokeratin; feline; immunohistochemistry