title: Long noncoding RNAs-related diseases, cancers, and drugs.
abstract: Long noncoding RNA (lncRNA) function is described in terms of related gene expressions, diseases, and cancers as well as their polymorphisms. Potential modulators of lncRNA function, including clinical drugs, natural products, and derivatives, are discussed, and bioinformatic resources are summarized. The improving knowledge of the lncRNA regulatory network has implications not only in gene expression, diseases, and cancers, but also in the development of lncRNA-based pharmacology.
authors.affiliation: Department of Radiation Oncology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Jen-Yang
authors.initials: JY
authors.lastname: Tang
authors.forename: Jin-Ching
authors.initials: JC
authors.lastname: Lee
authors.forename: Yung-Ting
authors.initials: YT
authors.lastname: Chang
authors.forename: Ming-Feng
authors.initials: MF
authors.lastname: Hou
authors.forename: Hurng-Wern
authors.initials: HW
authors.lastname: Huang
authors.forename: Chih-Chuang
authors.initials: CC
authors.lastname: Liaw
authors.forename: Hsueh-Wei
authors.initials: HW
authors.lastname: Chang
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D015195:Drug Design; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000235:genetics*; D062085:RNA, Long Noncoding / Q000235:genetics*
chemical_list: D000970:Antineoplastic Agents; D062085:RNA, Long Noncoding