title: Umbilical artery serum chitotriosidase concentration in pregnancies complicated by preeclampsia and relationship between chitotriosidase levels and fetal blood flow velocity.
abstract: OBJECTIVE
  To evaluate the significance of umbilical cord chitotriosidase concentrations in pregnancies with mild preeclampsia and explore the relationship between fetal chitotriosidase levels and fetal blood flow velocity.
  
  
  METHODS
  The study population included control group (n=40) and study group with mild preeclampsia (n=40). Umbilical cord blood samples were collected immediately after delivery. Umbilical artery (UA) flow velocity waveform was determined just before delivery.
  
  
  RESULTS
  Umbilical cord chitotriosidase levels and UA S/D rate were significantly high in preeclamptic group.
  
  
  CONCLUSIONS
  Chitotriosidase may be useful biochemical marker of fetal compromise that reflects the severity of fetoplacental blood flow resistance in pregnancies complicated by preeclampsia.
authors.affiliation: Department of Obstetrics and Gynecology, Kayseri Training and Education Hospital of Medicine , Kayseri , Turkey .
authors.forename: Ülkü
authors.initials: Ü
authors.lastname: Aksoy
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Aksoy
authors.forename: Gökhan
authors.initials: G
authors.lastname: Açmaz
authors.forename: Mustafa
authors.initials: M
authors.lastname: Babayiğit
authors.forename: Ömer
authors.initials: Ö
authors.lastname: Kandemir
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001783:Blood Flow Velocity; D016022:Case-Control Studies; D005260:Female; D005312:Fetal Blood; D006596:Hexosaminidases / Q000097:blood*; D006801:Humans; D021041:Placental Circulation; D011225:Pre-Eclampsia / Q000201:enzymology* / Q000503:physiopathology; D011247:Pregnancy; D014469:Umbilical Arteries; D055815:Young Adult
chemical_list: D015415:Biomarkers; D006596:Hexosaminidases; C086400:chitotriosidase