title: New method of analyzing NIRS data from prefrontal cortex at rest.
abstract: The aim of this study was to develop a simple technique for objective assessment of mental stress levels by measuring hemoglobin concentration changes in the bilateral prefrontal cortex (PFC) at rest, employing two-channel near-infrared spectroscopy (NIRS). Each subject was instructed to think about nothing in particular for 3 min and then to complete the State-Trait Anxiety Inventory (STAI) test. Next, NIRS measurements were taken and the left/right asymmetry of PFC activity at rest was evaluated by calculating the proposed Laterality Index at Rest (LIR). There was a significant positive correlation between the LIR and STAI score in 39 subjects. The present method allowed evaluation of mental stress level from NIRS data in the PFC at rest.
authors.affiliation: Department of Electrical Engineering and Bioscience, Waseda University, Tokyo, Japan. ishikawa10@matsumoto.eb.waseda.ac.jp.
authors.forename: Wakana
authors.initials: W
authors.lastname: Ishikawa
authors.affiliation: Department of Electrical Engineering and Bioscience, Waseda University, Tokyo, Japan.
authors.forename: Masakaze
authors.initials: M
authors.lastname: Sato
authors.affiliation: Department of Electrical Engineering and Bioscience, Waseda University, Tokyo, Japan.
authors.forename: Yukikatsu
authors.initials: Y
authors.lastname: Fukuda
authors.affiliation: Department of Electrical Engineering and Bioscience, Waseda University, Tokyo, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsumoto
authors.affiliation: Department of Neurological Surgery, Division of Optical Brain Engineering, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: Naohiro
authors.initials: N
authors.lastname: Takemura
authors.affiliation: Department of Neurological Surgery, Division of Optical Brain Engineering, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: Takeo
authors.initials: T
authors.lastname: Tsujii
authors.affiliation: Department of Neurological Surgery, Division of Optical Brain Engineering, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: Kaoru
authors.initials: K
authors.lastname: Sakatani
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D017397:Prefrontal Cortex / Q000502:physiology* / Q000503:physiopathology; D012146:Rest / Q000502:physiology*; D019265:Spectroscopy, Near-Infrared / Q000379:methods; D013315:Stress, Psychological / Q000378:metabolism* / Q000503:physiopathology*; D055815:Young Adult
chemical_list: D006454:Hemoglobins