title: Two cases of male breast cancer at a university hospital in southeast Brazil.
abstract: We report two rare cases of breast cancer in men treated with modified radical mastectomy. The patients were aged 67 and 45 years at the time of diagnosis. Tumor sizes were 2 cm and 8 cm in the older and younger patient, respectively. The histopathologic diagnosis was infiltrating ductal carcinoma in the first patient and infiltrating papillary carcinoma in the second patient. Immunohistochemical tests demonstrated estrogen and progesterone receptor positivity and HER2/c-erbB-2 negativity in both cases. The rarity of these cases is noted, in view of their uncommon occurrence at an early age in men and their immunophenotypic positivity, similar to breast cancer in women.
authors.affiliation: Pathology Service, Pathology Department, Hospital Universitário Antonio Pedro, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil.
authors.forename: Fabiana Resende
authors.initials: FR
authors.lastname: Rodrigues
authors.forename: André Vallejo
authors.initials: AV
authors.lastname: da Silva
authors.forename: Calina Maria Loures
authors.initials: CM
authors.lastname: de Oliveira Teixeira
authors.forename: Samantha Cunha Gomes
authors.initials: SC
authors.lastname: Antunes
authors.forename: Mayra Carrijo
authors.initials: MC
authors.lastname: Rochael
keywords: breast cancer; histopathology; immunohistochemistry; men; radical mastectomy