title: "Hidden" bone metastasis from thyroid carcinoma: a clinical note.
abstract: The (131)I-iodide ((131)I) whole-body scan, for thyroid carcinoma is at times difficult to interpret. In a diagnostic whole body (131)I scan of a patient with follicular carcinoma, a posterior skull lesion was partially hidden by overlapping facial structures. On lateral head view, the abnormality was clearly evident. SPECT/CT and MRI showed the lesion originated in the occipital bone and had enlarged into the posterior fossa. The mass was surgically removed and the patient received (131)I therapy for residual tissue. The study demonstrates a pitfall in the reading of two dimensional radioiodine images which can be overcome by SPECT or lateral imaging.
authors.affiliation: Nuclear Medicine Division, Department of Radiology and Imaging Sciences, Bethesda, MD, USA.
authors.forename: C
authors.initials: C
authors.lastname: Sioka
authors.affiliation: Diabetes, Obesity and Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA.
authors.forename: M C
authors.initials: MC
authors.lastname: Skarulis
authors.affiliation: Epidemiology Research Unit, Tropical Medicine Research, The University of the West Indies, Kingston, Jamaica.
authors.forename: M K
authors.initials: MK
authors.lastname: Tulloch-Reid
authors.affiliation: Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke, Bethesda, MD, USA.
authors.forename: J D
authors.initials: JD
authors.lastname: Heiss
authors.affiliation: Nuclear Medicine Division, Department of Radiology and Imaging Sciences, Bethesda, MD, USA. Electronic address: jreynolds@mail.cc.nih.gov.
authors.forename: J C
authors.initials: JC
authors.lastname: Reynolds
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000175:diagnosis / Q000556:secondary*; D018249:Adenoma, Oxyphilic / Q000175:diagnosis / Q000556:secondary*; D001859:Bone Neoplasms / Q000556:secondary; D003951:Diagnostic Errors; D005260:Female; D006111:Graves Disease / Q000150:complications; D006261:Headache / Q000209:etiology; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008371:Manubrium / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D064847:Multimodal Imaging; D009777:Occipital Bone / Q000000981:diagnostic imaging* / Q000473:pathology; D012888:Skull Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D013964:Thyroid Neoplasms / Q000150:complications / Q000473:pathology*; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D007457:Iodine Radioisotopes
keywords: (131)I-Iodide; Cáncer folicular de tiroides; Enfermedad metastásica; Follicular thyroid cancer; Metastatic disease; Radioiodine therapy; SPECT; Terapia con yodo radioactivo; Yodo radioactivo (131)I