title: The 3D genome shapes up for pluripotency.
abstract: Chromosome folding has been long associated with gene expression. Articles in Cell Stem Cell and Cell by Apostolou et al., (2013), Phillips-Cremins et al., (2013), Wei et al., (2013), and Zhang et al., (2013) uncover chromatin interaction networks linked to the establishment or maintenance of pluripotency and identify some responsible factors.
authors.affiliation: Institute of Human Genetics, UPR 1142, CNRS, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France.
authors.forename: Tom
authors.initials: T
authors.lastname: Sexton
authors.forename: Giacomo
authors.initials: G
authors.lastname: Cavalli
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins / Q000378:metabolism*; D019070:Cell Lineage; D065150:Cellular Reprogramming / Q000235:genetics*; D002843:Chromatin / Q000235:genetics* / Q000378:metabolism*; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism*; D002875:Chromosomes / Q000235:genetics*; D053595:Embryonic Stem Cells / Q000166:cytology*; D044127:Epigenesis, Genetic; D016678:Genome; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology*; D000090062:Kruppel-Like Factor 4; D051741:Kruppel-Like Transcription Factors / Q000378:metabolism*; D009687:Nuclear Proteins / Q000032:analysis*; D050814:Octamer Transcription Factor-3 / Q000378:metabolism*; D039904:Pluripotent Stem Cells / Q000166:cytology*; D000098550:Structural Maintenance of Chromosome Protein 1
chemical_list: D018797:Cell Cycle Proteins; D002843:Chromatin; D002868:Chromosomal Proteins, Non-Histone; D000090062:Kruppel-Like Factor 4; D051741:Kruppel-Like Transcription Factors; D009687:Nuclear Proteins; D050814:Octamer Transcription Factor-3; C494174:Pou5f1 protein, mouse; D000098550:Structural Maintenance of Chromosome Protein 1