title: Determination of trace levels of acetamide, propanamide, and butyramide in surface and drinking water using gas chromatography-mass spectrometry after derivatization with 9-xanthydrol.
abstract: A sensitive gas chromatographic mass spectrometric (GC-MS) method has been established for the simultaneous determination of acetamide (AA), propanamide (PA), and butyramide (BA) in surface and drinking water based on derivatization with 9-xanthydrol. Deuterated acrylamide was chosen as the internal standard for analyzing the water sample. The derivatization of AA, PA, and BA was performed directly in water and the reaction conditions (10.0-mM 9-xanthydrol, 0.5-M HCl, 20-min reaction time, and ambient temperature) were established. Under these conditions, the detection limit of the analytes was 0.03 μg L(-1), and the interday relative standard deviation was less than 16% at concentrations of 1.0, 5.0 and 10.0 μg L(-1). The proposed GC-MS method enables the reliable analysis of trace AA, PA, and BA in environmental water.
authors.affiliation: Department of Environmental Science, Kongju National University, Kongju 314-701, Republic of Korea.
authors.forename: Young-Hwan
authors.initials: YH
authors.lastname: Cho
authors.forename: Ho-Sang
authors.initials: HS
authors.lastname: Shin
mesh_terms: D000081:Acetamides / Q000032:analysis*; D000577:Amides / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D011422:Propionates / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*; D014966:Xanthenes / Q000737:chemistry*
chemical_list: D000081:Acetamides; D000577:Amides; D011422:Propionates; D014874:Water Pollutants, Chemical; D014966:Xanthenes; C009690:xanthydrol; C030686:acetamide; C006866:butyramide
keywords: Acetamide; Butyramide; Gas chromatography–mass spectrometry; Propanamide; Water; Xanthydrol derivatization