title: The positive impact of regular exercise program on stem cell mobilization prior to autologous stem cell transplantation.
abstract: OBJECTIVE
  The present study was planned to determine the effects of regular exercise program on hematopoietic stem cell (HSC) mobilization prior to autologous stem cell transplantation.
  
  
  METHODS
  Twenty-two consecutive patients were enrolled in the study. A regular 20 min exercise program was administered to the patients. The hematopoietic stem cell mobilization outcome, number of Granulocyte Colony-Stimulating Factor (G-CSF) and aphaeresis application days were compared with 20 case-matched controls who did not receive exercise program during HSC mobilization.
  
  
  RESULTS
  The median number of CD34(+) stem cells collected in the exercise and control groups were 8.15 × 10(6)/kg (range: 2.85-33.06 × 10(6)/kg) and 7.3 × 10(6)/kg (range: 1.78-25.9 × 10(6)/kg), respectively (p=0.696). G-CSF was administered for a median of 8 days (range, 5-10) in the exercise group and 8 days (range, 5-12) in the control group (p=0.848). The median apheresis duration was 1 day (range, 1-3) in both exercise and control groups (p=0.226).
  
  
  CONCLUSIONS
  Exercise seems to have a positive impact on stem cell mobilization though without statistical significance.
authors.affiliation: Department of Physiotherapy and Rehabilitation, Gazi University Faculty of Health Sciences, Ankara, Turkey. Electronic address: ilkekeser@yahoo.com.
authors.forename: Ilke
authors.initials: I
authors.lastname: Keser
authors.forename: Elif
authors.initials: E
authors.lastname: Suyani
authors.forename: Sahika Zeynep
authors.initials: SZ
authors.lastname: Aki
authors.forename: Ayhan Gulsan Turkoz
authors.initials: AG
authors.lastname: Sucak
mesh_terms: D000328:Adult; D064592:Autografts; D001781:Blood Component Removal; D015444:Exercise; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage*; D019650:Hematopoietic Stem Cell Mobilization; D006801:Humans; D008297:Male; D008875:Middle Aged; D033581:Stem Cell Transplantation
chemical_list: D016179:Granulocyte Colony-Stimulating Factor
keywords: Exercise; Hematopoietic stem cell; Mobilization; Physiotherapy; Stem cell transplantation