title: The relationship between type 2 diabetes family history, body composition and blood basal glycemia in sedentary people.
abstract: The aim of this study was to verify whether there is a positive correlation between family history to type 2 diabetes mellitus and body mass and composition, and alterations in blood basal glycaemia levels in sedentary male and female. Anthropometric variables, blood parameters, body composition and body surface area were evaluated on 183 male and 237 female sedentary individuals. Participants were classified into two groups: FH(+) (family history positive) and FH(-) (familiar history negative) according to their medical history. The FH(+) group showed higher values of body mass and body surface area than FH(-) group. These differences were statistically significant (p < 0.05) for the female subgroup. When compared to the FH(-) group, FH(+) female individuals showed a significantly greater fat mass (p < 0.01) and a significantly lower free fat mass-to-fat mass ratio (FFM/FM ratio) (p < 0.05). FH(+) female individuals showed significant lower levels of basal glucose values for Kg of FFM (p < 0.05), FM (p < 0.01) and BSA (p < 0.01) than FH(-) group. The results of this study indicate that body mass and composition correlate positively to family history to type 2 diabetes. The relationship between family history and body composition is particularly evident in young FH(+) female. Thus, as family history might represent a risk factor for the development of type 2 diabetes, this could be considered as an important parameter able to predict the onset of the disease itself. This knowledge could be used to improve preventive interventions (i.e. increasing levels of physical activity) promoting healthy lifestyle.
authors.affiliation: Sport and Exercise Sciences Research Unit, University of Palermo, Via Eleonora Duse 2, 90146, Palermo, Italy, antonino.bianco@unipa.it.
authors.forename: Antonino
authors.initials: A
authors.lastname: Bianco
authors.forename: Francesco
authors.initials: F
authors.lastname: Pomara
authors.forename: Margherita
authors.initials: M
authors.lastname: Raccuglia
authors.forename: Marianna
authors.initials: M
authors.lastname: Bellafiore
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Battaglia
authors.forename: Davide
authors.initials: D
authors.lastname: Filingeri
authors.forename: Antonio
authors.initials: A
authors.lastname: Paoli
authors.forename: Antonio
authors.initials: A
authors.lastname: Palma
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D001823:Body Composition; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology / Q000209:etiology; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors; D057185:Sedentary Behavior; D012737:Sex Factors; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D001786:Blood Glucose