title: New approach to managing genital warts.
abstract: OBJECTIVE
  To summarize and determine the appropriate use for the new and old management tools for genital warts.
  
  
  METHODS
  The following databases were searched: MEDLINE, PubMed, EMBASE, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, ACP Journal Club, and Trip. The bibliographies of retrieved papers were also reviewed. Clinical trials, qualitative review articles, consensus reports, and clinical practice guidelines were retrieved.
  
  
  RESULTS
  Symptomatic warts are prevalent in at least 1% of the population between the ages of 15 and 49, with estimates of up to 50% of the population being infected with human papillomavirus at some point in their lifetime. Imiquimod and podophyllotoxin are 2 new treatments for external genital warts that are less painful and can be applied by patients at home. In addition, the quadrivalent human papillomavirus vaccine has been shown to be efficacious in preventing genital warts and cervical cancer. There is still a role for the older treatment methods in certain situations, such as intravaginal, urethral, anal, or recalcitrant warts; or for pregnant patients.
  
  
  CONCLUSIONS
  The new treatments of external genital warts can reduce the pain of treatment and the number of office visits. Other treatment methods are still useful in certain situations.
authors.affiliation: Department of Family Medicine, University of Alberta, 205 College Plaza, Edmonton, AB T6G 2C8. c.lopaschuk@shaw.ca
authors.forename: Catharine C
authors.initials: CC
authors.lastname: Lopaschuk
mesh_terms: D000634:Aminoquinolines / Q000627:therapeutic use*; D002985:Clinical Protocols; D003218:Condylomata Acuminata / Q000188:drug therapy* / Q000628:therapy; D005260:Female; D006801:Humans; D000077271:Imiquimod; D030361:Papillomavirus Infections / Q000188:drug therapy* / Q000517:prevention & control; D053918:Papillomavirus Vaccines; D011034:Podophyllotoxin / Q000627:therapeutic use*; D011247:Pregnancy; D002583:Uterine Cervical Neoplasms / Q000517:prevention & control*
chemical_list: D000634:Aminoquinolines; D053918:Papillomavirus Vaccines; D011034:Podophyllotoxin; D000077271:Imiquimod