title: Mitochondrial genome of the natural tetraploid loach Misgurnus anguillicaudatus.
abstract: The mitochondrial genome of the natural tetraploid loach Misgurnus anguillicaudatus is a circular molecule of 16,645 bp in length, containing 13 protein-coding genes, 22 transfer RNA (tRNA) genes, two ribosomal RNA (rRNA) genes, and two main noncoding regions (the control region and the origin of the light strand replication). Most of the genes are encoded on the heavy strand, except for ND6 and eight tRNAs. All the protein-coding genes are initiated with ATG except for COX1, which began with GTG instead. However, the termination codons of 13 protein-coding genes are varied with TAA, TA-, T-- or TAG. The control region is 917 bp in length and located between the tRNA(Pro) and tRNA(Phe) genes, some typical conserved elements (TAS, CSB1-3 and CSB D-F) were found in this region. All these features reflect a typical vertebrate mitochondrial gene arrangement of the tetraploid M. anguillicaudatus.
authors.affiliation: College of Fisheries, Key Lab of Freshwater Animal Breeding, Ministry of Agriculture; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University , Wuhan, Hubei , P.R. China.
authors.forename: Yong-Yao
authors.initials: YY
authors.lastname: Yu
authors.forename: Yan-He
authors.initials: YH
authors.lastname: Li
authors.forename: Ru-Wei
authors.initials: RW
authors.lastname: Li
authors.forename: Wei-Min
authors.initials: WM
authors.lastname: Wang
authors.forename: Xiao-Yun
authors.initials: XY
authors.lastname: Zhou
mesh_terms: D000818:Animals; D001483:Base Sequence; D003531:Cypriniformes / Q000235:genetics*; D004272:DNA, Mitochondrial; D054629:Genome, Mitochondrial; D008969:Molecular Sequence Data; D011003:Ploidies; D012335:RNA, Ribosomal / Q000235:genetics; D012343:RNA, Transfer / Q000235:genetics; D017422:Sequence Analysis, DNA; D017423:Sequence Analysis, RNA
chemical_list: D004272:DNA, Mitochondrial; D012335:RNA, Ribosomal; D012343:RNA, Transfer