title: [Atypical mycobacterial infection after kidney transplant: two clinical cases].
abstract: Infections are an important cause of morbidity and mortality during kidney transplant. In areas where tuberculosis is not endemic, Mycobacteria other than tuberculosis (MOOT), also known as 'atypical' Mycobacteria, are more frequently involved in mycobacterial infections than M. tuberculosis. The incidence of MOOT infection in renal transplant recipients ranges from 0.16 to 0.38 percent. This low rate of reported incidence is, however, often due to delay in diagnosis and lack of therapeutic protocols. Further difficulty is caused by the interaction of antimycobacterial drugs with the post-transplant immunosuppressive regimen, necessitating close monitoring of plasma concentrations and careful dose modification. We present two cases of Mycobacterium Chelonae infection in kidney transplant recipients which differ in both clinical presentation and pharmacological approach.
authors.forename: Alessandra Antonia
authors.initials: AA
authors.lastname: Mele
authors.forename: G
authors.initials: G
authors.lastname: Bilancio
authors.forename: Remo
authors.initials: R
authors.lastname: Luciani
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Bellizzi
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Palladino
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology*; D016926:Mycobacterium chelonae / Q000302:isolation & purification; D012867:Skin / Q000187:drug effects / Q000473:pathology; D013640:Tarsal Joints / Q000473:pathology; D013848:Thigh / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000995:Antitubercular Agents; D007166:Immunosuppressive Agents