title: Thyroid Doppler indices in patients with sickle cell disease.
abstract: OBJECTIVE
  To evaluate the intrathyroidal hemodynamic changes and thyroidal volume in sickle cell disease (SCD) patients.
  
  
  METHODS
  Thirty-two patients with homozygous SCD and 32 control subjects were examined with color Doppler ultrasonography. None of the patients and control subjects had clinical or laboratory evidence of thyroid disease.
  
  
  RESULTS
  SCD patients had significantly higher resistance index (RI) and pulsatility index (PI) values and lower thyroid volume compared with control group.
  
  
  CONCLUSIONS
  Increased intrathyroidal RI and PI and decreased thyroid volume may be due to impaired thyroidal microcirculation. Further and follow-up studies are needed to explain the relationship between Doppler parameters and thyroid functions.
authors.affiliation: Mustafa Kemal University, Faculty of Medicine, Department of Radiology. Electronic address: sinemkarazincir@yahoo.com.
authors.forename: Sinem
authors.initials: S
authors.lastname: Karazincir
authors.forename: Ali
authors.initials: A
authors.lastname: Balci
authors.forename: Zafer
authors.initials: Z
authors.lastname: Yonden
authors.forename: Edip
authors.initials: E
authors.lastname: Gali
authors.forename: Turgay
authors.initials: T
authors.lastname: Daplan
authors.forename: Yeliz
authors.initials: Y
authors.lastname: Beyoglu
authors.forename: Hasan
authors.initials: H
authors.lastname: Kaya
authors.forename: Ertuğrul
authors.initials: E
authors.lastname: Egilmez
mesh_terms: D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000000981:diagnostic imaging*; D002648:Child; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D009929:Organ Size; D013961:Thyroid Gland / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology; D018615:Ultrasonography, Doppler, Color; D014655:Vascular Resistance; D055815:Young Adult
keywords: Doppler ultrasonography; Pulsatility index; Resistance index; Sickle cell disease; Thyroid