title: Correlates of health-related quality of life in French people with type 2 diabetes.
abstract: OBJECTIVE
  Diabetes is known to impair health-related quality of life (HrQol). Our aim was to analyse a comprehensive set of potential determinants of HrQol in a large sample of patients with diabetes.
  
  
  METHODS
  This study is based on the ENTRED 2007 study, a representative sample of adults (18 years and older) with diabetes. Data were extracted from postal self-reported questionnaires (from patients and medical practitioners) and from reimbursements from the National health insurance data system. HrQol was assessed with the MOS SF-12 for mental (MCS) and physical (PCS) component summaries. Multivariate linear regression models were used to analyse the variables associated with HrQol.
  
  
  RESULTS
  SF-12 MCS and PCS were available in 2832 patients with T2DM, with a mean age 64 years (1715 males, 56%). Lower income, severe hypoglycaemic episodes, hospitalisation ≥24 h, instrumental daily living (IADL) restriction, low satisfaction for social support and an HbA1c within the 8.1-10.0% range were associated with lower MCS rating, whereas an older age and male gender were associated with higher MCS. Older age, female sex, higher BMI, lower income, insulin treatment, macrovascular complications, severe hypoglycaemic episodes, hospitalisation ≥24 h, and IADL restriction were associated with lower PCS values whereas having no need for social support was associated with higher PCS values.
  
  
  CONCLUSIONS
  HrQol associated factors are multiple but mainly linked with socio-demographic factors, diabetes complications and satisfaction for social support. A patient centred approach should be tested to prevent impairment of HrQol and thus to decrease the burden of diabetes. Assessment of social support should be included.
authors.affiliation: Pole de gérontologie clinique, CHU Bordeaux, France. isabelle.bourdel-marchasson@chu-bordeaux.fr
authors.forename: I
authors.initials: I
authors.lastname: Bourdel-Marchasson
authors.forename: C
authors.initials: C
authors.lastname: Druet
authors.forename: C
authors.initials: C
authors.lastname: Helmer
authors.forename: E
authors.initials: E
authors.lastname: Eschwege
authors.forename: P
authors.initials: P
authors.lastname: Lecomte
authors.forename: M
authors.initials: M
authors.lastname: Le-Goff
authors.forename: A J
authors.initials: AJ
authors.lastname: Sinclair
authors.forename: A
authors.initials: A
authors.lastname: Fagot-Campagna
mesh_terms: D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012944:Social Support; D011795:Surveys and Questionnaires
keywords: Diabetes; Health related quality of life; Social support