title: Thyroid MIBG uptake in Parkinson's disease with diabetes mellitus.
abstract: In our work, we investigated thyroid and cardiac MIBG uptake as potential differential markers. We observed reduced cardiac uptake of MIBG in PD and diabetic CAN, in agreement with the previous studies. However, there was a significant difference between the PD and diabetic cardiac autonomic neuropathy groups with respect to early and delayed thyroid MIBG uptake, in that reduced thyroid MIBG uptake was seen in PD but not in diabetic autonomic neuropathy. We therefore propose that this parameter could be a marker for identifying parkinsonism when it presents together with DM.
authors.affiliation: Department of Neurology, Gangneung Asan Hospital, University of Ulsan, College of Medicine, Bangdong-ri, Sacheon-myeon, Gangneung-si, Gangwon-do, 210-711, Korea.
authors.forename: Wooyoung
authors.initials: W
authors.lastname: Jang
authors.forename: Joong-Seok
authors.initials: JS
authors.lastname: Kim
authors.forename: Jin Whan
authors.initials: JW
authors.lastname: Cho
authors.forename: Jin Young
authors.initials: JY
authors.lastname: Ahn
authors.forename: Yun Young
authors.initials: YY
authors.lastname: Choi
authors.forename: Hee-Tae
authors.initials: HT
authors.lastname: Kim
mesh_terms: D019797:3-Iodobenzylguanidine / Q000493:pharmacokinetics*; D000368:Aged; D048909:Diabetes Complications / Q000000981:diagnostic imaging*; D003929:Diabetic Neuropathies / Q000000981:diagnostic imaging / Q000378:metabolism; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000378:metabolism; D010300:Parkinson Disease / Q000150:complications / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D013961:Thyroid Gland / Q000000981:diagnostic imaging* / Q000378:metabolism*
chemical_list: D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine