title: SugarBind database (SugarBindDB): a resource of pathogen lectins and corresponding glycan targets.
abstract: SugarBindDB lists pathogen and biotoxin lectins and their carbohydrate ligands in a searchable format. Information is collected from articles published in peer-reviewed scientific journals. Help files guide the user through the search process and provide a review of structures and names of sugars that appear in human oligosaccharides. Glycans are written in the condensed form of the carbohydrate nomenclature system developed by the International Union of Pure and Applied Chemistry (IUPAC). Since its online publication by The MITRE Corporation in 2005, the database has served as a resource for research on the glycobiology of infectious disease. SugarBindDB is currently hosted by the Swiss Institute of Bioinformatics on the ExPASy server and will be enhanced and linked to related resources as part of the wider UniCarbKB initiative. Enhancements will include the option to display glycans in a variety of formats, including modified 2D condensed IUPAC and symbolic nomenclature.
authors.affiliation: Department of Surgery, University of Chicago Medical Center, Chicago, IL, USA.
authors.forename: Baddr
authors.initials: B
authors.lastname: Shakhsheer
authors.forename: Mark
authors.initials: M
authors.lastname: Anderson
authors.forename: Khaled
authors.initials: K
authors.lastname: Khatib
authors.forename: Leelapavan
authors.initials: L
authors.lastname: Tadoori
authors.forename: Lokesh
authors.initials: L
authors.lastname: Joshi
authors.forename: Frederique
authors.initials: F
authors.lastname: Lisacek
authors.forename: Lynette
authors.initials: L
authors.lastname: Hirschman
authors.forename: Elaine
authors.initials: E
authors.lastname: Mullen
mesh_terms: D001426:Bacterial Proteins; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D030562:Databases, Protein; D006017:Glycolipids / Q000737:chemistry; D006023:Glycoproteins / Q000737:chemistry; D006801:Humans; D037102:Lectins / Q000737:chemistry*; D008969:Molecular Sequence Data; D011134:Polysaccharides / Q000737:chemistry*; D011485:Protein Binding; D014584:User-Computer Interface
chemical_list: D001426:Bacterial Proteins; D006017:Glycolipids; D006023:Glycoproteins; D037102:Lectins; D011134:Polysaccharides
keywords: Adhesin; database; glycan; hemagglutinin; infection; lectin; oligosaccharide; pathogen