title: Design, synthesis and evaluation of stationary phases for improved achiral supercritical fluid chromatography separations.
abstract: A series of novel stationary phases for improved Supercritical Fluid Chromatography (SFC) separation of achiral mixtures is described. Several of these stationary phases show chromatographic performance and generality that is comparable with that of the best commercial stationary phases currently available. The effects of stationary phase structure on chromatographic performance and generality are considered, and suggestions for further improvements in this important field are offered.
authors.affiliation: Automated Synthesis & Purifications, Merck Research Laboratories, West Point, PA, USA. ray_mcclain@merck.com
authors.forename: Ray
authors.initials: R
authors.lastname: McClain
authors.forename: Myung Ho
authors.initials: MH
authors.lastname: Hyun
authors.forename: Yinan
authors.initials: Y
authors.lastname: Li
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Welch
mesh_terms: D025924:Chromatography, Supercritical Fluid / Q000379:methods*; D015394:Molecular Structure; D013237:Stereoisomerism
keywords: Achiral SFC; Multipoint interactions; Stationary phases