title: Overview of liquid handling instrumentation for high-throughput screening applications.
abstract: Liquid handling in the laboratory has unique challenges specific to the types of research being performed. The devices employed for purposes of performing liquid handling can be broken down into three general categories: bulk reagent dispensers, transfer devices, and plate washers. An overview of these types of liquid handlers, as well as common features and relevance to high-throughput applications, are discussed in this article. Important topics such as sterility, ease of use, cost, and instrument design advantages and disadvantages are also covered. Curr. Protoc. Chem Biol. 1:43-54. © 2009 by John Wiley & Sons, Inc.
authors.affiliation: ICCB-Longwood Screening Facility, Harvard Medical School, Boston, Massachusetts.
authors.forename: Stewart
authors.initials: S
authors.lastname: Rudnicki
authors.forename: Sean
authors.initials: S
authors.lastname: Johnston
keywords: high throughput screening (HTS); laboratory automation; liquid handling; plate filler; plate washer