title: Three-dimensional reconstruction of subject-specific knee joint using computed tomography and magnetic resonance imaging image data fusions.
abstract: Three-dimensional reconstruction of human body from a living subject can be considered as the first step toward promoting virtual human project as a tool in clinical applications. This study proposes a detailed protocol for building subject-specific three-dimensional model of knee joint from a living subject. The computed tomography and magnetic resonance imaging image data of knee joint were used to reconstruct knee structures, including bones, skin, muscles, cartilages, menisci, and ligaments. They were fused to assemble the complete three-dimensional knee joint. The procedure was repeated three times with respect to three different methods of reference landmarks. The accuracy of image fusion in accordance with different landmarks was evaluated and compared with each other. The complete three-dimensional knee joint, which included 21 knee structures, was accurately developed. The choice of external or anatomical landmarks was not crucial to improve image fusion accuracy for three-dimensional reconstruction. Further work needs to be done to explore the value of the reconstructed three-dimensional knee joint for its biomechanics and kinematics.
authors.affiliation: Department of Joint Surgery, the First People's Hospital of Lianyungang, Lianyungang, China.
authors.forename: Yuefu
authors.initials: Y
authors.lastname: Dong
authors.forename: Zhifang
authors.initials: Z
authors.lastname: Mou
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Huang
authors.forename: Guanghong
authors.initials: G
authors.lastname: Hu
authors.forename: Yinghai
authors.initials: Y
authors.lastname: Dong
authors.forename: Qingrong
authors.initials: Q
authors.lastname: Xu
mesh_terms: D000328:Adult; D003198:Computer Simulation; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D007719:Knee Joint / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D008297:Male; D008953:Models, Anatomic; D064847:Multimodal Imaging / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D011859:Radiography; D013382:Subtraction Technique
keywords: Computed tomography; image fusion; knee joint; magnetic resonance imaging; three-dimensional reconstruction