title: Placement in an acidic environment increase the solubility of white mineral trioxide aggregate.
abstract: OBJECTIVE
  The aim of the present study was to evaluate solubility of white mineral trioxide aggregate (WMTA) in an acidic environment.
  
  
  METHODS
  Twenty-four metal rings were prepared, filled with WMTA and randomly divided into two groups. The samples in groups 1 and 2 were set in synthetic tissue fluid with pH values of 7.4 and 4.4, respectively and then were transferred to beakers containing synthetic tissue fluid with pH values of 7.7 and 4.4. Solubility of WMTA samples were calculated at the 9 experimental intervals. Data was analyzed with two-factor ANOVA and Bonferroni test (P < 0.03).
  
  
  RESULTS
  The total solubility of WMTA in groups 1 and 2 were -9.1796 ± 1.9158% and -1.1192 ± 2.6236%, (P = 0.028) with weight changes of 9.1574 ± 2.1432% and 7.3276 ± 1.5823%, respectively (P = 0.002). Statistical analysis revealed significant differences between the two groups.
  
  
  CONCLUSIONS
  It was concluded that solubility of WMTA increases in acidic environments and additional therapeutic precautions should be taken to decrease inflammation in endodontic treatment.
authors.affiliation: Department of Endodontic, Tabriz Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: Hamid Reza
authors.initials: HR
authors.lastname: Yavari
authors.forename: Zahra
authors.initials: Z
authors.lastname: Borna
authors.forename: Saeed
authors.initials: S
authors.lastname: Rahimi
authors.forename: Shahriar
authors.initials: S
authors.lastname: Shahi
authors.forename: Hadi
authors.initials: H
authors.lastname: Valizadeh
authors.forename: Morteza
authors.initials: M
authors.lastname: Ghojazadeh
keywords: Acidic environment; mineral trioxide aggregate; pH; solubility