title: Long-acting Preparations in Substance Abuse Management: A Review and Update.
abstract: Many pharmacological approaches have been used in managing substance use disorders. Conventional pharmacological agents have relatively short durations of action which make them vulnerable to non-adherence and relapse to substance use disorder. To overcome this problem, long-acting preparations have been developed with the aim of reducing the frequency of use and hence improving adherence. This review takes a broad overview of the long-acting preparations available for the management of substance use disorders. The pharmacology, advantages and disadvantages of these preparations are discussed. Many of these preparations hold promise for improving patient outcomes.
authors.affiliation: Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Aditya
authors.initials: A
authors.lastname: Hegde
authors.forename: Shubh Mohan
authors.initials: SM
authors.lastname: Singh
authors.forename: Siddharth
authors.initials: S
authors.lastname: Sarkar
keywords: Depots; implants; long acting preparations; pharmacoprophylaxis; substance use disorders