title: Management of locally aggressive mandibular tumours using a gas combination cryosurgery.
abstract: This study evaluated the results of curettage followed by cryosurgery using a combination of propane, butane, and isobutane gas for several benign but locally aggressive bone tumours on the mandible. Twenty-nine patients (16 men and 13 women) participated in the study. Patient ages ranged from 6 to 87 years (mean, 23.72 years). Before enucleation and cryosurgery, some patients received prior treatment consisting of marsupialisation to decrease tumour size. Twenty-seven of the 29 patients (93.10%) showed no evidence of clinical or radiographic recurrence after treatment through enucleation and cryosurgery. Wound dehiscence, which was observed in all cases, healed by second intention. The average follow-up period was 70.55 months (range, 53-120 months). These results suggest that enucleation followed by cryosurgery is an effective therapy for managing locally aggressive mandible tumours. In addition, this treatment is a less expensive intervention than more radical procedures.
authors.affiliation: Department of Dentistry (Head: PhD, Fabrício Mesquita Tuji), Ophir Loyola Hospital, Belém, PA, Brazil; Avenida Governador Magalhães Barata (Head: PhD, Fabrício Mesquita Tuji), 992, Belém, PA 66063-240, Brazil.
authors.forename: José Thiers
authors.initials: JT
authors.lastname: Carneiro
authors.affiliation: Department of Dentistry (Head: PhD, Fabrício Mesquita Tuji), Ophir Loyola Hospital, Belém, PA, Brazil; Avenida Governador Magalhães Barata (Head: PhD, Fabrício Mesquita Tuji), 992, Belém, PA 66063-240, Brazil; School of Dentistry, Federal University of Pará-UFPA, Belém, PA, Brazil. Electronic address: alinecarreira@hotmail.com.
authors.forename: Aline Semblano Carreira
authors.initials: AS
authors.lastname: Falcão
authors.affiliation: Department of Dentistry (Head: PhD, Fabrício Mesquita Tuji), Ophir Loyola Hospital, Belém, PA, Brazil; Avenida Governador Magalhães Barata (Head: PhD, Fabrício Mesquita Tuji), 992, Belém, PA 66063-240, Brazil.
authors.forename: Ana Karla
authors.initials: AK
authors.lastname: da Silva Tabosa
authors.affiliation: Department of Dentistry (Head: PhD, Fabrício Mesquita Tuji), Ophir Loyola Hospital, Belém, PA, Brazil; Avenida Governador Magalhães Barata (Head: PhD, Fabrício Mesquita Tuji), 992, Belém, PA 66063-240, Brazil; Albert Einstein Hospital, São Paulo, SP, Brazil.
authors.forename: Elio Hitoshi
authors.initials: EH
authors.lastname: Shinohara
authors.affiliation: Department of Dentistry (Head: PhD, Fabrício Mesquita Tuji), Ophir Loyola Hospital, Belém, PA, Brazil; Avenida Governador Magalhães Barata (Head: PhD, Fabrício Mesquita Tuji), 992, Belém, PA 66063-240, Brazil.
authors.forename: Lucas Machado
authors.initials: LM
authors.lastname: de Menezes
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000564:Ameloblastoma / Q000601:surgery; D002073:Butanes / Q000627:therapeutic use*; D002648:Child; D003452:Cryosurgery / Q000379:methods*; D003475:Curettage / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000601:surgery*; D008875:Middle Aged; D009808:Odontogenic Tumors / Q000601:surgery; D011407:Propane / Q000627:therapeutic use*; D012189:Retrospective Studies; D013529:Surgical Wound Dehiscence / Q000209:etiology; D014945:Wound Healing / Q000502:physiology; D055815:Young Adult
chemical_list: D002073:Butanes; C046888:butane; D011407:Propane
keywords: Cryosurgery; Cryotherapy; Jaw neoplasms