title: Diffusion-weighted imaging and positron emission tomography in various cytological subtypes of primary lung adenocarcinoma.
abstract: The purpose of the study was to retrospectively characterize diffusion-weighted magnetic resonance imaging (DWI) and positron emission tomography for differentiating among the various cytological subtypes of primary lung adenocarcinomas. The maximum diffusion signal intensities and the maximum standardized uptake value (SUV max) of 31 lesions were analyzed after delineation of regions of interest on the images. Diffusion intensities were 0.934 for Clara type, 0.938 for type II type, 1.473 for nongoblet type, and 1.617 for poorly differentiated adenocarcinoma type based on Shimosato's cytological classification (P=.020). The SUV max values were 4.926, 5.491, 5.709, and 12.132, respectively (P=.044). DWI might reflect some of the cytological characteristics of the tumor cells for differentiating the subtypes of lung adenocarcinomas.
authors.affiliation: Department of Surgery, Kyorin University School of Medicine, Tokyo, Japan; Department of Thoracic Surgery, Gunma Prefectural Cancer Center, Gunma, Japan. Electronic address: t-ryota@kpb.biglobe.ne.jp.
authors.forename: Ryota
authors.initials: R
authors.lastname: Tanaka
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Nakazato
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Horikoshi
authors.forename: Shigeru
authors.initials: S
authors.lastname: Tsuchida
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Yoshida
authors.forename: Yoko
authors.initials: Y
authors.lastname: Nakazato
authors.forename: Keisei
authors.initials: K
authors.lastname: Tachibana
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Kondo
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Goya
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D000077192:Adenocarcinoma of Lung; D000368:Aged; D000369:Aged, 80 and over; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012189:Retrospective Studies
chemical_list: D019788:Fluorodeoxyglucose F18
keywords: Cytological subtypes; Diffusion-weighted imaging; Lung adenocarcinoma; Magnetic resonance imaging; Positron emission tomography