title: Expression of taste signal transduction molecules in the caecum of common marmosets.
abstract: The extraoral presence of taste signal transduction proteins has recently been reported in rodents and humans. Here, we report for the first time the presence of these signal transduction proteins in the caecum of a non-human primate, the common marmoset. Quantitative RT-PCR data on the gene expression of taste signal transduction molecules (gustducin and TRPM5) in common marmosets suggested high expression in the caecum, which was not observed in other non-human primates. Immunohistochemical analysis confirmed the specific presence of gustducin and taste receptors in marmoset caecal cells. These results may relate to the specific feeding behaviour of marmosets, which consume plant exudates, primarily gums.
authors.affiliation: Faculty of Applied Biological Sciences, Gifu University, , 1-1 Yanagido, Gifu, Gifu 501-1193, Japan.
authors.forename: Sae
authors.initials: S
authors.lastname: Gonda
authors.forename: Shuichi
authors.initials: S
authors.lastname: Matsumura
authors.forename: Shoichiro
authors.initials: S
authors.lastname: Saito
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Go
authors.forename: Hiroo
authors.initials: H
authors.lastname: Imai
mesh_terms: D000818:Animals; D002144:Callithrix / Q000235:genetics / Q000502:physiology*; D002432:Cecum / Q000378:metabolism*; D016663:Cercopithecinae / Q000235:genetics / Q000502:physiology; D003106:Colon / Q000378:metabolism*; D005247:Feeding Behavior; D005786:Gene Expression Regulation; D007150:Immunohistochemistry; D060888:Real-Time Polymerase Chain Reaction; D043562:Receptors, G-Protein-Coupled / Q000235:genetics / Q000378:metabolism; D012453:Saimiri / Q000235:genetics / Q000502:physiology; D015398:Signal Transduction; D013045:Species Specificity; D050053:TRPM Cation Channels / Q000235:genetics / Q000378:metabolism; D055697:Taste Perception; D015293:Transducin / Q000235:genetics / Q000378:metabolism
chemical_list: D043562:Receptors, G-Protein-Coupled; D050053:TRPM Cation Channels; C075192:gustducin; D015293:Transducin
keywords: New World monkey; Old World monkey; common marmoset