title: [The studies on clinical value of AFP-L3 detected by microspincolum method for judgment of treatment response in patients with HCC undergoing TACE].
abstract: OBJECTIVE
  To explore the clinical value of Lens culinaris agglutinin-reactive alpha-fetoprotein detected by microspincolum method for judgment of treatment response in patients with hepatocellular carcinoma undergoing transcatheter arterial chemoembolization.
  
  
  METHODS
  Twenty eight patients with HCC undergoing TACE follow-up in hospital were recruited. AFP and AFP-L3 were measured in all the patients before and after TACE, and correlations were analyzed between AFP-L3% and response to treatment.
  
  
  RESULTS
  Among the twenty eight patients with HCC undergoing TACE, 8 out 11 case in AFP-L3% descent group had well treatment response, 5 out 17 case in AFP-L3% elevated group had well treatment response(Chi2 = 4. 858, P < 0. 05).
  
  
  CONCLUSIONS
  The detection of AFP-L3 by microspincolum method is useful to judgment of treatment response in patients with HCC undergoing TACE.
authors.affiliation: Zejiang University, Hangzhou, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhou
authors.forename: Hong-ming
authors.initials: HM
authors.lastname: Pan
authors.forename: Gong-ying
authors.initials: GY
authors.lastname: Chen
authors.forename: Meng-fei
authors.initials: MF
authors.lastname: Zhu
authors.forename: Xiong-ying
authors.initials: XY
authors.lastname: Zhu
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.forename: Bai-lu
authors.initials: BL
authors.lastname: Ren
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000737:chemistry* / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000737:chemistry* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D000509:alpha-Fetoproteins / Q000032:analysis*
chemical_list: D000509:alpha-Fetoproteins