title: Cortical mapping of 3D optical topography in infants.
abstract: Precise localisation of cortical activation in the early development of the infant brain remains unclear. It is challenging to co-register haemodynamic responses during functional activation in infants with the underlying anatomy of the brain. We used a multispectral imaging algorithm to reconstruct 3D optical topographic images of haemodynamic responses in an infant during voice processing. In this chapter, we present a method for co-registering 3D optical topography images reconstructed from functional activation data in infants onto anatomical brain images obtained from MRI structurals of the individual infants.
authors.affiliation: Biomedical Optics Research Laboratory, Medical Physics and Bioengineering, University College London, London, UK. m.papademetriou@ucl.ac.uk.
authors.forename: Maria D
authors.initials: MD
authors.lastname: Papademetriou
authors.affiliation: Department of Psychology, University of South Carolina, Columbia, SC, USA.
authors.forename: John
authors.initials: J
authors.lastname: Richards
authors.affiliation: Biomedical Optics Research Laboratory, Medical Physics and Bioengineering, University College London, London, UK.
authors.forename: Teresa
authors.initials: T
authors.lastname: Correia
authors.affiliation: Centre for Brain and Cognitive Development, Birkbeck College, London, UK.|Department of Neurodevelopmental Science, Institute of Psychiatry, Kings College, London, UK.
authors.forename: Anna
authors.initials: A
authors.lastname: Blasi
authors.affiliation: Department of Neurodevelopmental Science, Institute of Psychiatry, Kings College, London, UK.
authors.forename: Declan G
authors.initials: DG
authors.lastname: Murphy
authors.affiliation: Centre for Brain and Cognitive Development, Birkbeck College, London, UK.
authors.forename: Sarah
authors.initials: S
authors.lastname: Lloyd-Fox
authors.affiliation: Centre for Brain and Cognitive Development, Birkbeck College, London, UK.
authors.forename: Mark H
authors.initials: MH
authors.lastname: Johnson
authors.affiliation: Biomedical Optics Research Laboratory, Medical Physics and Bioengineering, University College London, London, UK.
authors.forename: Clare E
authors.initials: CE
authors.lastname: Elwell
mesh_terms: D000465:Algorithms; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D007223:Infant; D008279:Magnetic Resonance Imaging / Q000379:methods*