title: Efficient synthesis of imino-methano Tröger bases by nitrene insertions into C-N bonds.
abstract: A direct nitrene insertion into C-N bonds is observed upon treatment of methano-Tröger bases with arylsulfonyl iminophenyliodinanes under copper and dirhodium catalysis. Novel cyclic imino-methano Tröger bases are obtained (55-88%). Enantiopure products (ee ≥ 99%) can be obtained with tailored substrates.
authors.affiliation: University of Geneva, Department of Organic Chemistry, 30 Quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland.
authors.forename: Sandip A
authors.initials: SA
authors.lastname: Pujari
authors.forename: Laure
authors.initials: L
authors.lastname: Guénée
authors.forename: Jérôme
authors.initials: J
authors.lastname: Lacour