title: Body mass index, cholecystitis, cholelithiasis, pancreatitis and imaging of common bile duct stones.
abstract: OBJECTIVE
  Studies to date have not investigated whether body mass index (BMI) affects the sensitivity and specificity of magnetic resonance cholangiopancreatography (MRCP). The purpose of this study was to investigate the effect of BMI and also concomitant pancreatitis, cholecystitis and cholelithiasis on the sensitivity and specificity of MRCP.
  
  
  METHODS
  Between January 2004 and December 2011, 185 patients were included in the study and divided into 3 groups according to BMI as normal, overweight or obese. Both MRCP and endoscopic retrograde cholangiopancreatography (ERCP) were performed in all patients. ERCP was accepted as the "gold standard." The accuracy, sensitivity and specificity values of the 3 groups were calculated to determine any effects on the results of the MRCP.
  
  
  RESULTS
  Before separating into groups according to BMI, the statistical results for MRCP in the detection of stone disease were as follows: specificity 74.3%, sensitivity 81.7% and accuracy 79%. After dividing the patients into 3 groups according to BMI, the specificity of stone detection with MRCP in the normal-weight group was 93.8% but decreased to 65.5% in the overweight group and to 72% in the obese group. The sensitivity of stone detection with MRCP in the normal-weight group was 85.2% but decreased to 75% in the overweight group and increased to 88.9% in the obese group. The accuracy was 88.3% in the normal-weight group but decreased to 71.6% in the overweight group and to 81.9% in the obese group.
  
  
  CONCLUSIONS
  Our study showed that MRCP performance was decreased in the overweight and obese groups.
authors.affiliation: Departments of Radiology (GC, EY), Gastroenterology (SG, ZC), and General Surgery (ET), Baskent University Faculty of Medicine, Konya; and Department of Statistics and Computer Science (MA), Baskent University Faculty of Science and Letters, Ankara, Turkey.
authors.forename: Gökçen
authors.initials: G
authors.lastname: Coban
authors.forename: Erkan
authors.initials: E
authors.lastname: Yildirim
authors.forename: Savaş
authors.initials: S
authors.lastname: Göktürk
authors.forename: Zuhal
authors.initials: Z
authors.lastname: Calişkan
authors.forename: Emin
authors.initials: E
authors.lastname: Türk
authors.forename: Mehtap
authors.initials: M
authors.lastname: Akçil
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D049448:Cholangiopancreatography, Magnetic Resonance / Q000379:methods* / Q000592:standards; D002764:Cholecystitis / Q000175:diagnosis* / Q000453:epidemiology; D002769:Cholelithiasis / Q000175:diagnosis* / Q000453:epidemiology; D003135:Common Bile Duct / Q000473:pathology; D005260:Female; D042882:Gallstones / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000175:diagnosis / Q000453:epidemiology; D010195:Pancreatitis / Q000175:diagnosis* / Q000453:epidemiology; D055815:Young Adult