title: Magnetic particle imaging scanner with 10-kHz drive-field frequency.
abstract: Magnetic particle imaging (MPI) can be used as a fast diagnostic method for obtaining three-dimensional images from inside the body of small animals by the use of functionalized magnetic nanoparticles as tracer. Here, we present our scanner setup working at 10-kHz drive-field frequency to sample a field of view of 22 × 22 × 15 mm(3) with up to 32 volume images per second. A resolution of about 1 × 2 × 1 mm(3) is achieved with iron oxide nanoparticles (Resovist). We discuss the properties of the complete system for application in imaging small animals such as mice.
authors.forename: Meinhard
authors.initials: M
authors.lastname: Schilling
authors.forename: Frank
authors.initials: F
authors.lastname: Ludwig
authors.forename: Christian
authors.initials: C
authors.lastname: Kuhlmann
authors.forename: Thilo
authors.initials: T
authors.lastname: Wawrzik
mesh_terms: D000818:Animals; D003287:Contrast Media; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007089:Image Enhancement / Q000295:instrumentation / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000662:veterinary*; D058185:Magnetite Nanoparticles; D051379:Mice; D057054:Molecular Imaging / Q000295:instrumentation* / Q000662:veterinary*; D019047:Phantoms, Imaging; D051381:Rats; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D058185:Magnetite Nanoparticles