title: [Peri-viability: limits of prematurity in a regional hospital in the last 10 years].
abstract: OBJECTIVE
  To determine the preterm viability between 22 and 25 gestational weeks in our hospital in last 10 years.
  
  
  METHODS
  A descriptive retrospective study was conducted on preterms between 22-25 gestational weeks born between 1-1-2002 and 12-31-2011.
  
  
  RESULTS
  There were 121 newborns, 45 (37%) stillbirths and 76 (63%) live births (16 died in delivery room, and 60 admitted to neonatal intensive unit). Among the 60 admitted, 34 died before hospital discharge, and 26 survived (21% of total, 34% of live births and 43% of those admitted to neonatal intensive unit). The causes of death were: 16 therapeutic effort limitation in delivery room, 8 therapeutic effort limitation in neonatal ward, 7 nosocomial sepsis, 7 NEC, 4 respiratory problems, and 8 of unknown cause. There were no survivors below 24 gestational weeks. Of the 26 survivors, 4 had major neurological disorders, and 11 with a normal neurological outcome. No significant statistical differences were found in the mortality between the two five-year periods analysed.
  
  
  CONCLUSIONS
  The peri-viability has important clinical and ethical problems for neonatologist.
authors.affiliation: Servicio de Neonatología, Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, SESPA, Oviedo, España. Electronic address: gsolis@telefonica.net.
authors.forename: G
authors.initials: G
authors.lastname: Solís Sánchez
authors.affiliation: Servicio de Neonatología, Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, SESPA, Oviedo, España.
authors.forename: C
authors.initials: C
authors.lastname: Pérez González
authors.affiliation: Servicio de Neonatología, Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, SESPA, Oviedo, España.
authors.forename: E
authors.initials: E
authors.lastname: García López
authors.affiliation: Servicio de Neonatología, Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, SESPA, Oviedo, España.
authors.forename: M
authors.initials: M
authors.lastname: Costa Romero
authors.affiliation: Servicio de Neonatología, Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, SESPA, Oviedo, España.
authors.forename: R P
authors.initials: RP
authors.lastname: Arias Llorente
authors.affiliation: Servicio de Neonatología, Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, SESPA, Oviedo, España.
authors.forename: M
authors.initials: M
authors.lastname: Suárez Rodríguez
authors.affiliation: Servicio de Neonatología, Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, SESPA, Oviedo, España.
authors.forename: B
authors.initials: B
authors.lastname: Fernández Colomer
authors.affiliation: Servicio de Neonatología, Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, SESPA, Oviedo, España.
authors.forename: G D
authors.initials: GD
authors.lastname: Coto Cotallo
mesh_terms: D005260:Female; D005328:Fetal Viability; D005865:Gestational Age; D006761:Hospitals; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D012189:Retrospective Studies; D013030:Spain; D013997:Time Factors
keywords: Extreme prematurity; Limit of viability; Límite de la viabilidad; Prematuridad extrema; Supervivencia; Survival