title: Orbital myositis associated with celiac disease.
abstract: A 26-year-old female patient presented with redness, lid edema on the right eye and diplopia on left gaze. There was a minimal limitation of adduction of the right eye, accompanied with pain and diplopia. Orbital magnetic resonance imaging confirmed the diagnosis of orbital myositis. Anti-endomysial immunoglobulin (Ig) A, anti-endomysial IgG, anti-gliadin IgA and anti-tissue transglutaminase IgG antibodies were positive, while other tests for autoimmune diseases were unremarkable. The patient stated that her diarrhea had been relieved by a gluten-free diet. Methylprednisolone therapy (1 mg/kg) was started and on her next visit her complaints were relieved. Later, methotrexate (15 mg/week) was added to the therapy as the patient became steroid-dependent, and she has been attack-free for the last 3 months under methotrexate and low-dose methylprednisolone (4 mg/day) treatment. Associations between orbital myositis and various autoimmune diseases have previously been reported. We report here the first case of associated orbital myositis and celiac disease.
authors.affiliation: Department of Ophthalmology, Marmara University School of Medicine, Istanbul, Turkey, erencerman@yahoo.com.
authors.forename: Eren
authors.initials: E
authors.lastname: Cerman
authors.forename: Fehim
authors.initials: F
authors.lastname: Esen
authors.forename: Muhsin
authors.initials: M
authors.lastname: Eraslan
authors.forename: Haluk
authors.initials: H
authors.lastname: Kazokoglu
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002446:Celiac Disease / Q000150:complications*; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D055622:Orbital Myositis / Q000209:etiology*; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone