title: Normal tissue dose and second cancer risk due to megavoltage fan-beam CT, static tomotherapy and helical tomotherapy in breast radiotherapy.
abstract: This study investigates the dose from the 1mm collimator width megavoltage fan-beam CT (fine, normal and coarse pitch) available on tomotherapy as well as for whole-breast tomotherapy treatments. The BEIR VII lifetime attributable risk model was utilised to assess the significance of the imaging dose relative to the treatment dose.
authors.affiliation: Northern Sydney Cancer Centre, Royal North Shore Hospital, Australia; Centre for Medical Radiation Physics, University of Wollongong, Australia; Liverpool Cancer Therapy Centre, Liverpool Hospital, Australia. Electronic address: aq908@uowmail.edu.au.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Quinn
authors.forename: Lois
authors.initials: L
authors.lastname: Holloway
authors.forename: Nicholas
authors.initials: N
authors.lastname: Hardcastle
authors.forename: Wolfgang A
authors.initials: WA
authors.lastname: Tomé
authors.forename: Anatoly
authors.initials: A
authors.lastname: Rosenfeld
authors.forename: Peter
authors.initials: P
authors.lastname: Metcalfe
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy*; D054893:Cone-Beam Computed Tomography / Q000009:adverse effects*; D005260:Female; D006801:Humans; D016609:Neoplasms, Second Primary / Q000209:etiology* / Q000473:pathology; D019047:Phantoms, Imaging; D011834:Radiation Monitoring / Q000379:methods; D011874:Radiometry; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000009:adverse effects / Q000379:methods; D011882:Radiotherapy, High-Energy / Q000009:adverse effects* / Q000379:methods; D061089:Radiotherapy, Image-Guided / Q000009:adverse effects / Q000379:methods; D050397:Radiotherapy, Intensity-Modulated / Q000009:adverse effects* / Q000379:methods; D012016:Reference Values; D018570:Risk Assessment; D036542:Tomography, Spiral Computed / Q000009:adverse effects
keywords: Breast; Cancer risk; Dose; Megavoltage CT; Tomotherapy