title: [New synthesis of highly selective inhibitor of histone deacetylase 6--N-hydroxy-4-(2-methyl-1,2,3,4-tetrahydro-pyrido[4,3b]indol-5-ylmethyl)benzamide--Tubastatin A].
abstract: A four-stage synthesis of highly selective inhibitor of histone deacetylase 6--Tubastatin A was carried out. Convenient and safety reaction conditions were used throughout the synthesis.
authors.forename: M V
authors.initials: MV
authors.lastname: Kozlov
authors.forename: A A
authors.initials: AA
authors.lastname: Kleĭmenova
authors.forename: K A
authors.initials: KA
authors.lastname: Konduktorov
authors.forename: S N
authors.initials: SN
authors.lastname: Kochetkov
mesh_terms: D001549:Benzamides / Q000737:chemistry; D056572:Histone Deacetylase Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry; D006655:Histone Deacetylases / Q000737:chemistry / Q000378:metabolism*; D006877:Hydroxamic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D001549:Benzamides; D056572:Histone Deacetylase Inhibitors; D006877:Hydroxamic Acids; D007211:Indoles; C553587:tubastatin A; C037689:benzamide; D006655:Histone Deacetylases