title: Kaposi's sarcoma and pregnancy: case report and literature review.
abstract: We report the observation of cutaneous Kaposi's sarcoma (KS) worsening during the second trimester of pregnancy in 2 African women. Both patients were tested seronegative for HIV. They had no complication during their pregnancy, and no evidence of extracutaneous disease was found, allowing therapeutic abstention. They gave birth to healthy children showing no clinical evidence of human herpesvirus 8 (HHV-8) infection. Based on these observations and on the review of the literature, we discuss the risk of vertical transmission of HHV-8 as well as the impact of pregnancy on KS.
authors.affiliation: Department of Dermatology, APHP St Louis Hospital, University Paris Diderot, Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Brunet-Possenti
authors.forename: C
authors.initials: C
authors.lastname: Pages
authors.forename: R
authors.initials: R
authors.lastname: Rouzier
authors.forename: N
authors.initials: N
authors.lastname: Dupin
authors.forename: M
authors.initials: M
authors.lastname: Bagot
authors.forename: C
authors.initials: C
authors.lastname: Lebbé
mesh_terms: D000328:Adult; D018450:Disease Progression; D005260:Female; D006566:Herpesviridae Infections / Q000635:transmission* / Q000821:virology; D019288:Herpesvirus 8, Human; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D050498:Live Birth; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000821:virology; D012514:Sarcoma, Kaposi / Q000473:pathology* / Q000821:virology; D012878:Skin Neoplasms / Q000473:pathology* / Q000821:virology; D055815:Young Adult