title: Lipofibroadenoma of the thymus: a case report.
abstract: We observed an unusual case of Lipofibroadenoma (LFA) in the anterior mediastinum with a 21-year-old man, who was detected with a mass on a chest X-ray scan for one month. Thymothymectomy was then performed and the mass was excised completely, in which the tumor was histologically composed of epithelial cells, lymphocytes, mature adipose and fibrous tissue. Within the tumor, the fat cells was distributed singly or multifocally under the ground of fibro tissue with hyaline degeneration, and the epithelial cells were arranged as crack structure with lymphocytes infiltrated sparsely. By immunohistochemical staining assay, the epithelial cells were positive for AE1/AE3 and CK19, and the lymphocytes were CD3 and CD20 positive. Based on the histological characters, a diagnosis of LFA was made, and the total follow-up period was determined to be forty six months. The final repeated CT scan revealed no recurring or residual lesions were detected during the post-surgical course.
  The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1500429801911703.
authors.affiliation: Department of Pathology, Affiliated Yantai Yuhuangding Hospital, Medical College of Qingdao University, No,20, Yuhuangding East Road, Yantai 264000, PR China.
authors.forename: Guimei
authors.initials: G
authors.lastname: Qu
authors.forename: Guohua
authors.initials: G
authors.lastname: Yu
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhang
authors.forename: Junjie
authors.initials: J
authors.lastname: Ma
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Wang
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D018226:Fibroadenoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008067:Lipoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008297:Male; D013934:Thymectomy; D013953:Thymus Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor