title: Laparoscopically assisted vaginal radical hysterectomy: systematic review of the literature.
abstract: Laparoscopically assisted vaginal radical vaginal hysterectomy (LAVRH), a minimally invasive technique that seems to be an attractive alternative to traditional surgery, remains unexplored in the treatment of cervical cancer. We searched Medline (1966-2013) and Scopus (2004-2013) search engines, as well as reference lists from all included studies. Ten studies were retrieved; including 6 retrospective cohort studies, 2 prospective cohort studies, 1 retrospective randomized trial, and a phase II randomized control trial. LAVRH provided equal recurrence-free rates when performed in patients with tumors not exceeding 2 cm in greatest diameter. Its main advantages seem to be less intraoperative blood loss and more radical pelvic lymphadenectomy. The primary disadvantages of the technique are a higher rate of disease-positive surgical margins, resulting in the need for adjuvant therapy, and the slow learning curve required for a surgeon to gain expertise. With use in minimally invasive surgery of newer techniques such as total laparoscopic radical hysterectomy and robotic-assisted radical hysterectomy, and possible future adoption of more conservative techniques such as cervical conization with pelvic lymphadenectomy, the question remains as to whether LAVRH will be adopted by the surgical community or lost to oblivion.
authors.affiliation: Department of Gynecologic Oncology, 1st Department of Obstetrics and Gynecology, Alexandra Maternity Hospital, University of Athens Medical School, Chalandri, Greece. Electronic address: pergialiotis@yahoo.gr.
authors.forename: Vassileios
authors.initials: V
authors.lastname: Pergialiotis
authors.forename: Alexandros
authors.initials: A
authors.lastname: Rodolakis
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Christakis
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Thomakos
authors.forename: Georgios
authors.initials: G
authors.lastname: Vlachos
authors.forename: Aristides
authors.initials: A
authors.lastname: Antsaklis
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000379:methods*; D010535:Laparoscopy / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: Coelio-Schauta; LAVRH; Radical hysterectomy; Vaginal; Wertheim