title: Novel polymorphisms in CYP4F2 and VKORC1 may lead to adaptations to the warfarin-dosage algorithm.
mesh_terms: D000465:Algorithms; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics; D000072470:Cytochrome P450 Family 4; D004305:Dose-Response Relationship, Drug; D005838:Genotype; D006801:Humans; D010597:Pharmacogenetics / Q000639:trends*; D064417:Vitamin K Epoxide Reductases / Q000235:genetics; D014859:Warfarin / Q000008:administration & dosage
chemical_list: D014859:Warfarin; D003577:Cytochrome P-450 Enzyme System; D000072470:Cytochrome P450 Family 4; C117480:CYP4F2 protein, human; C578523:VKORC1 protein, human; D064417:Vitamin K Epoxide Reductases