title: Homolytic substitution at phosphorus for C-P bond formation in organic synthesis.
abstract: Organophosphorus compounds are important in organic chemistry. This review article covers emerging, powerful synthetic approaches to organophosphorus compounds by homolytic substitution at phosphorus with a carbon-centered radical. Phosphination reagents include diphosphines, chalcogenophosphines and stannylphosphines, which bear a weak P-heteroatom bond for homolysis. This article deals with two transformations, radical phosphination by addition across unsaturated C-C bonds and substitution of organic halides.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan ; ACT-C, Japan Science and Technology Agency, Sakyo-ku, Kyoto 606-8502, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Yorimitsu
keywords: addition; free radical; homolysis; phosphine; radical; substitution