title: Enantio- and regioselective conjugate addition of organometallic reagents to linear polyconjugated nitroolefins.
abstract: The copper-catalysed conjugate addition of trialkylaluminium and dialkylzinc reagents to polyconjugated nitroolefins (nitrodiene and nitroenyne derivatives) is reported. A reversed Josiphos ligand L7 allows for the selective 1,4- or 1,6-addition with high enantioselectivities.
authors.affiliation: Department of Organic Chemistry, Université de Genève, 30, Quai Ernest Ansermet, 1211 Genève-4, Switzerland.
authors.forename: Matthieu
authors.initials: M
authors.lastname: Tissot
authors.forename: Alexandre
authors.initials: A
authors.lastname: Alexakis
keywords: asymmetric catalysis; conjugate addition; copper; ligand effects; phosphine ligands