title: Creutzfeldt-Jakob Disease in the hospital setting: a case report and review.
abstract: Rapidly progressive dementia is a neurological condition that results in subacute deterioration in cognitive, behavioral and motor function. The most serious diagnosis for a patient with rapidly progressive dementia is Creutzfeldt-Jakob Disease (CJD), a prion-related illness that typically results in death within one year. However, there are numerous autoimmune, infectious and toxic-metabolic causes of rapidly progressive dementia that are potentially reversible with treatment. Thus, the differential diagnosis for a rapidly progressive dementia is critically important. In this article, the authors discuss a case of CJD diagnosed at a St. Paul hospital to illustrate the differential diagnosis of rapidly progressive dementia and highlight the role of neuroimaging.
authors.affiliation: University of Minnesota, USA.
authors.forename: Pezhman
authors.initials: P
authors.lastname: Roohani
authors.forename: Manish K
authors.initials: MK
authors.lastname: Saha
authors.forename: Michael
authors.initials: M
authors.lastname: Rosenbloom
mesh_terms: D015415:Biomarkers / Q000134:cerebrospinal fluid; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis*; D003704:Dementia / Q000209:etiology; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D018450:Disease Progression; D004562:Electrocardiography; D005260:Female; D006760:Hospitalization; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009460:Neurologic Examination; D011328:Prions / Q000134:cerebrospinal fluid; D012815:Signal Processing, Computer-Assisted
chemical_list: D015415:Biomarkers; D011328:Prions