title: Asthma: beyond corticosteroid treatment.
abstract: Asthma is one of the most common chronic diseases in the world, affecting over 300 million people. It is an inflammatory disorder characterized by bronchoconstriction and airway hyperresponsiveness, followed by inflammatory manifestations in the respiratory system. The prevalence of asthma is rising and there is a clinical need to develop more effective treatments. While corticosteroids (glucocorticosteroids) remain the mainstay of asthma therapy, they have limitations because of their potentially severe side-effects and the presence of corticosteroid resistance in some patients. This review discusses current strategies in the treatment of asthma and considers new therapeutic regimens of asthma in the drug development pipeline.
authors.affiliation: Department of Pharmacology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Yasser
authors.initials: Y
authors.lastname: Marandi
authors.forename: Neda
authors.initials: N
authors.lastname: Farahi
authors.forename: Goudarz Sadeghi
authors.initials: GS
authors.lastname: Hashjin
keywords: asthma; corticosteroids; inflammation