title: Prevalence and risk factors of posterior vitreous detachment in a Chinese adult population: the Handan eye study.
abstract: BACKGROUND
  To describe the prevalence and associations of posterior vitreous detachment (PVD) in a rural adult Chinese population.
  
  
  METHODS
  All eligible subjects were requested to carry out a comprehensive eye examination; PVD was a pre-specified outcome variable and was determined via biomicroscopical examination (slit-lamp biomicroscopy) with a +90-D preset lens after mydriasis. Prevalence was standardized to China population census (2000).
  
  
  RESULTS
  5890 (86.2%) subjects completed the examination of slit-lamp biomicroscopy with a +90-D lens. PVD was present in 160 participants (2.7%); the standardized prevalence was 2.0% (95% confidence interval [CI], 1.6-2.3%). PVD developed increasingly with age (P for trend < 0.001) for both men and women. Using a multivariate regression model, older people were found to run a higher risk of developing PVD than younger people, and women were found to have a higher risk than men (OR, 2.9; 95% CI, 1.5-5.9). Diabetes, hypertension, smoking, drinking, and intraocular pressure (IOP) were not significantly associated with PVD.
  
  
  CONCLUSIONS
  About one in fifty people is found to have PVD in this population-based study. Age and female are independently associated with PVD occurrence.
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Shen
authors.forename: Xinrong
authors.initials: X
authors.lastname: Duan
authors.forename: Fenghua
authors.initials: F
authors.lastname: Wang
authors.forename: Ningli
authors.initials: N
authors.lastname: Wang
authors.forename: Yi
authors.initials: Y
authors.lastname: Peng
authors.forename: David T L
authors.initials: DT
authors.lastname: Liu
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Peng
authors.forename: Sizhen
authors.initials: S
authors.lastname: Li
authors.forename: Yuanbo
authors.initials: Y
authors.lastname: Liang
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D015995:Prevalence; D012307:Risk Factors; D012424:Rural Population; D012737:Sex Factors; D020255:Vitreous Detachment / Q000453:epidemiology*