title: Facile and efficient synthesis of new class of imidazole derivatives via one-pot multicomponent reactions in water.
abstract: A water-accelerated multicomponent synthesis of organic target molecules has been used as a key method for the preparation of novel imidazole derivatives. The three-component condensation reactions of primary amines with trichloroacetonitrile in the presence of ninhydrine in water are developed as efficient and clean green synthetic procedures for the high-yielding preparation of imidazoles.
authors.affiliation: Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran. zshossaini@yahoo.com.
authors.forename: Zinatossadat
authors.initials: Z
authors.lastname: Hossaini
authors.forename: Samereh
authors.initials: S
authors.lastname: Seyfi
authors.forename: Faramarz
authors.initials: F
authors.lastname: Rostami-Charati
authors.forename: Mehdi
authors.initials: M
authors.lastname: Ghambarian
mesh_terms: D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D021241:Spectrometry, Mass, Electrospray Ionization; D014867:Water / Q000737:chemistry*
chemical_list: D007093:Imidazoles; D014867:Water