title: Nonbacterial thrombotic endocarditis leading to acute heart failure due to aortic stenosis in a patient with lung cancer.
abstract: We herein report an autopsied case of a patient with adenocarcinoma of the lungs who developed nonbacterial thrombotic endocarditis (NBTE) that caused acute heart failure (AHF) due to acute aortic stenosis (AS). A 37-year-old man was admitted to our hospital due to chest pain and fever. He was diagnosed as having Stage IV lung cancer. Following the administration of chemotherapy, the patient presented with acute onset of dyspnea. He was diagnosed with having AHF based on his clinical course and physical findings, and ultimately he died without responding to treatment. The autopsy revealed that NBTE caused acute AS leading to AHF.
authors.affiliation: Department of Respirology, Tokyo Saiseikai Central Hospital, Japan. daisuketaniyama@gmail.com
authors.forename: Daisuke
authors.initials: D
authors.lastname: Taniyama
authors.forename: Ryusuke
authors.initials: R
authors.lastname: Yamamoto
authors.forename: Maki
authors.initials: M
authors.lastname: Kawasaki
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Kamata
authors.forename: Keisuke
authors.initials: K
authors.lastname: Miyamoto
authors.forename: Shuko
authors.initials: S
authors.lastname: Mashimo
authors.forename: Fumio
authors.initials: F
authors.lastname: Sakamaki
mesh_terms: D000208:Acute Disease; D000230:Adenocarcinoma / Q000150:complications / Q000601:surgery; D000328:Adult; D001024:Aortic Valve Stenosis / Q000150:complications* / Q000601:surgery; D004696:Endocarditis / Q000150:complications* / Q000601:surgery; D006331:Heart Diseases / Q000150:complications* / Q000601:surgery; D006333:Heart Failure / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000601:surgery; D008297:Male; D013927:Thrombosis / Q000150:complications* / Q000601:surgery