title: Distilled water peritoneal lavage in patients with rupture hepatocellular carcinoma.
abstract: OBJECTIVE
  Intra-peritoneal lavage is well known and used in intra-peritoneal malignancy However, the clinical role for patients with rupture of HCC has not yet been established. The aim of this study was to evaluate the clinical value of intraoperative peritoneal lavage for patients with rupture of HCC.
  
  
  METHODS
  A retrospective study of operative findings, other factors, and outcome was performed in 66 patients with rupture of HCC who underwent distilled water peritoneal lavage (DWPL) during hepatectomy.
  
  
  RESULTS
  There was a trend towards a higher intra-peritoneal, extra-hepatic recurrence rate in patients without DWPL. Patients who underwent DWPL had a significantly better 5-year disease-free survival rate than control group, 11.5±4.6 months and 30.2±8.4 months (p=0.018), respectively, and better overall survival rate, 21.7±6.2 months, than control group, 57.3±11.2 months (p=0.001).
  
  
  CONCLUSIONS
  DWPL during liver resection retards tumor recurrence and improves the intraoperative survival rate in patients with spontaneously ruptured HCC.
authors.affiliation: Department of Surgery, National Defense Medical Center, Taipei, Taiwan, Republic of China.
authors.forename: Yuan-Min
authors.initials: YM
authors.lastname: Chang
authors.forename: Kuo-Feng
authors.initials: KF
authors.lastname: Hsu
authors.forename: Jyh-Cherng
authors.initials: JC
authors.lastname: Yu
authors.forename: De-Chuan
authors.initials: DC
authors.lastname: Chan
authors.forename: Cheng-Jueng
authors.initials: CJ
authors.lastname: Chen
authors.forename: Teng-Wei
authors.initials: TW
authors.lastname: Chen
authors.forename: Chung-Bao
authors.initials: CB
authors.lastname: Hsieh
authors.forename: Huan Fa
authors.initials: HF
authors.lastname: Hsieh
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000628:therapy*; D057168:Distillation; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010533:Peritoneal Lavage; D012189:Retrospective Studies; D012422:Rupture, Spontaneous; D015996:Survival Rate; D014867:Water
chemical_list: D014867:Water