title: Oxygen Releasing Biomaterials for Tissue Engineering.
abstract: Due to the increasing demand to generate thick and vascularized tissue engineered constructs, novel strategies are currently being developed. An emerging example is the generation of oxygen-releasing biomaterials to tackle mass transport and diffusion limitations within engineered tissue-like constructs. Biomaterials containing oxygen releasing molecules can be fabricated in various forms such as, hybrid thin films, microparticles, or three dimensional (3D) scaffolds. In this perspective, we will summarize various oxygen-releasing reagents and their potential applications in regenerative engineering. Moreover, we will review the main approaches to fabricate oxygen-releasing biomaterials for a range of tissue engineering applications.
authors.affiliation: Center for Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA ; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.
authors.forename: Gulden
authors.initials: G
authors.lastname: Camci-Unal
authors.forename: Neslihan
authors.initials: N
authors.lastname: Alemdar
authors.forename: Nasim
authors.initials: N
authors.lastname: Annabi
authors.forename: Ali
authors.initials: A
authors.lastname: Khademhosseini
keywords: cell survival; oxygen-releasing biomaterials; peroxides; tissue engineering