title: Pulsed ultrasound modulated optical tomography utilizing the harmonic response of lock-in detection.
abstract: Ultrasound modulated optical tomography (USMOT) can image the optical properties of a scattering medium at a spatial resolution approaching that of ultrasound (US). A lock-in parallel speckle detection technique is proposed to detect pulsed US modulated light using a multipixel detector. The frequency components of the pass band match those of the US pulse train and provide efficient detection. The modulation depth is extracted by taking the difference between a pair of speckle patterns modulated by a pair of phase-inversed US bursts. Modification to pulse inversion mode enables the second harmonic US modulation due to nonlinear US propagation to be detected.
authors.affiliation: Electrical Systems and Optics Research Division, Faculty of Engineering, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
authors.forename: H
authors.initials: H
authors.lastname: Ruan
authors.forename: M L
authors.initials: ML
authors.lastname: Mather
authors.forename: S P
authors.initials: SP
authors.lastname: Morgan
mesh_terms: D000162:Acoustics; D003198:Computer Simulation; D005583:Fourier Analysis; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008027:Light; D055095:Optics and Photonics; D019047:Phantoms, Imaging; D012542:Scattering, Radiation; D041622:Tomography, Optical / Q000295:instrumentation* / Q000379:methods; D014465:Ultrasonics; D014463:Ultrasonography / Q000379:methods*