title: Long-term follow-up of gastric adenocarcinoma with chief cell differentiation using upper gastrointestinal tract endoscopy.
abstract: During upper endoscopic screening, a 71-year-old asymptomatic woman was found to have a small, yellowish, superficial elevated lesion in the upper third of her stomach, without any signs of atrophic mucosa. The patient underwent endoscopic follow-up once a year for approximately five years; however, changes in the tumor were barely detectable. Endoscopic mucosal resection was performed, and a histological examination confirmed the diagnosis of gastric adenocarcinoma with chief cell differentiation (GA-CCD). GA-CCD is rare; therefore, its clinicopathological features remain unknown. This case suggests that only barely detectable endoscopic changes may be observed in GA-CCD during long-term follow-up.
authors.affiliation: Department of Gastroenterology, Oita Kouseiren Tsurumi Hospital, Japan. takashi0315@oita-u.ac.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Abe
authors.forename: Takayuki
authors.initials: T
authors.lastname: Nagai
authors.forename: Junji
authors.initials: J
authors.lastname: Fukunaga
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Okawara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nakashima
authors.forename: Mitsutaka
authors.initials: M
authors.lastname: Syutou
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Kajimoto
authors.forename: Ryojin
authors.initials: R
authors.lastname: Wake
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Oyama
authors.forename: Takashi
authors.initials: T
authors.lastname: Yao
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D000368:Aged; D002454:Cell Differentiation / Q000502:physiology; D019872:Chief Cells, Gastric / Q000473:pathology*; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D013997:Time Factors