title: Nematicidal enzymes from microorganisms and their applications.
abstract: Microorganisms can attack and kill nematodes by diverse processes such as capturing, parasitizing, and producing toxins and enzymes. Extracellular enzymes, including serine proteases, chitinases, and collagenases are shown to be important virulence factors that can degrade the main chemical constituents of the nematode cuticle and eggshell. Here, we review the structure, function, regulation, and evolution of these nematicidal enzymes and provide insights into the mechanisms of microbial infections against nematodes. We discuss the practical applications of these nematicidal enzymes in agriculture and other areas.
authors.affiliation: Laboratory for Conservation and Utilization of Bio-Resources, and Key Laboratory of Microbial Diversity in Southwest China, Ministry of Education, Yunnan University, Kunming 650091, People's Republic of China.
authors.forename: Jinkui
authors.initials: J
authors.lastname: Yang
authors.forename: Lianming
authors.initials: L
authors.lastname: Liang
authors.forename: Juan
authors.initials: J
authors.lastname: Li
authors.forename: Ke-Qin
authors.initials: KQ
authors.lastname: Zhang
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000378:metabolism*; D001419:Bacteria / Q000201:enzymology* / Q000472:pathogenicity; D005658:Fungi / Q000201:enzymology* / Q000472:pathogenicity; D006836:Hydro-Lyases / Q000378:metabolism*; D009348:Nematoda / Q000187:drug effects* / Q000382:microbiology; D037521:Virulence Factors / Q000378:metabolism*
chemical_list: D000969:Antinematodal Agents; D037521:Virulence Factors; D006836:Hydro-Lyases