title: Comparison of detection and quantification of HBV DNA in chronic HBeAg negative and positive patients by Abbott RealTime HBV and Roche Cobas TaqMan HBV assays.
abstract: Monitoring the serum hepatitis B viral DNA levels with sensitive realtime PCR assays is strongly recommended for the management of patients with chronic HBV infection. This study compares the performance of two realtime HBV quantitative PCR assays with samples from chronic HBeAg(+) and HBeAg(-) patients.
authors.affiliation: University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA.
authors.forename: Carol J
authors.initials: CJ
authors.lastname: Morris
authors.forename: Mary
authors.initials: M
authors.lastname: Hill
authors.forename: Maria
authors.initials: M
authors.lastname: de Medina
authors.forename: Christine
authors.initials: C
authors.lastname: Herman
authors.forename: Gavin A
authors.initials: GA
authors.lastname: Cloherty
authors.forename: Paul
authors.initials: P
authors.lastname: Martin
mesh_terms: D004279:DNA, Viral / Q000097:blood* / Q000235:genetics; D006513:Hepatitis B e Antigens / Q000097:blood*; D006515:Hepatitis B virus / Q000235:genetics / Q000302:isolation & purification*; D019694:Hepatitis B, Chronic / Q000821:virology*; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D060888:Real-Time Polymerase Chain Reaction; D019562:Viral Load / Q000379:methods*
chemical_list: D004279:DNA, Viral; D006513:Hepatitis B e Antigens
keywords: Abbott RealTime HBV assay; Cobas TaqMan HBV assay; HBV viral load; HBeAg negative; HBeAg positive