title: Cardiac troponin-T in acute pericarditis.
abstract: BACKGROUND
  The long-term outcome of acute pericarditis with high cardiac troponin-T (cTnT) is unknown. Our purpose was to investigate the prognostic and clinical value of cTnT in myopericardial inflammatory syndromes.
  
  
  METHODS
  Between January 2001 and September 2011, 107 patients hospitalized for acute pericarditis or myopericarditis were enrolled. Postinfarction pericarditis and neoplastic pericarditis were excluded. Physical examination, ECG, echocardiography and blood tests were performed.
  
  
  RESULTS
  Among the 105 patients (89% men, mean age 36 ± 15 years-old), a cTnT rise was detectable in 64 patients (60.9%). Only younger age was found as an independent factor for higher values of cTnT in multivariate analysis (P = 0.03). After a mean follow-up of 51 months, a similar rate of complications was found in patients with a positive or a negative cTnT test: recurrent pericarditis (11 vs. 19%, P = 0.23) and cardiac tamponade (2 vs. 5%, P = 0.56). No cases of constrictive pericarditis, residual left ventricular dysfunction or hospital death were detected. The left ventricular ejection fraction remained unchanged during the follow-up (62.6 ± 6.5 vs. 61.9 ± 5.8, P = 0.89).
  
  
  CONCLUSIONS
  In acute pericarditis, a cTnT rise is a frequent finding and commonly found in younger patients. However, unlike acute coronary syndrome, cTnT rise is not a negative prognostic marker.
authors.affiliation: aDepartment of Cardiology bIntensive Care Unit, Jerez Hospital, Jerez, Spain.
authors.forename: Sergio
authors.initials: S
authors.lastname: Gamaza-Chulián
authors.forename: Javier
authors.initials: J
authors.lastname: León-Jiménez
authors.forename: María
authors.initials: M
authors.lastname: Recuerda-Núñez
authors.forename: Santiago
authors.initials: S
authors.lastname: Camacho-Freire
authors.forename: Alejandro
authors.initials: A
authors.lastname: Gutiérrez-Barrios
authors.forename: José C
authors.initials: JC
authors.lastname: Vargas-Machuca
mesh_terms: D000208:Acute Disease; D000328:Adult; D015415:Biomarkers / Q000097:blood; D002305:Cardiac Tamponade / Q000097:blood / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010493:Pericarditis / Q000097:blood* / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D013318:Stroke Volume; D013997:Time Factors; D020107:Troponin T / Q000097:blood*; D015854:Up-Regulation; D016277:Ventricular Function, Left; D055815:Young Adult
chemical_list: D015415:Biomarkers; C545568:TNNT2 protein, human; D020107:Troponin T