title: Delivering and phenotyping mouse models for the respiratory community: a report on the Biochemical Society Workshop.
abstract: The IMPC (International Mouse Phenotyping Consortium) was launched recently, and its aim is to develop and phenotype mouse knockouts of 4000 genes over the next 5 years and, ultimately, of all 20000 or so genes in the mouse genome. As part of the IMPC, the MRC (Medical Research Council) also launched a call for MRC mouse networks, where groups of U.K.-based researchers could form a consortium based around a particular area of research. Members of the respiratory research community formed the RDDRC (Respiratory Development and Disease Research Consortium) to consolidate and develop respiratory phenotyping methods suitable for high-throughput screening. This paper, arising from a Biochemical Society workshop held in London in 2012, highlights the purposes of the RDDRC and the needs of the respiratory research community.
authors.affiliation: Leukocyte Biology, National Heart and Lung Institute, Imperial College London, UK. c.dean@imperial.ac.uk
authors.forename: Charlotte
authors.initials: C
authors.lastname: Dean
authors.forename: Colin
authors.initials: C
authors.lastname: Bingle
authors.forename: Matthew
authors.initials: M
authors.lastname: Hind
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D007391:International Cooperation; D051379:Mice; D018345:Mice, Knockout / Q000235:genetics*; D020380:Needs Assessment; D010641:Phenotype; D012140:Respiratory Tract Diseases / Q000235:genetics*