title: An 'inflammatory' variant of solar purpura: a simulant of leukocytoclastic vasculitis and neutrophilic dermatoses.
abstract: To study the clinical and pathological features of cases of apparent solar purpura, with attention to the recently described phenomenon of inflammatory changes within otherwise typical lesions.
  
  
  
  We studied 95 cases diagnosed as solar purpura and identified 10 cases (10.5%) in which significant neutrophilic inflammation was present, potentially simulating a leukocytoclastic vasculitis or neutrophilic dermatosis. An additional three cases were identified in subsequent routine practice. The clinical features, including follow-up for subsequent development of vasculitis and histological features were studied.
  
  
  
  In all cases the histological features were typical of solar purpura, with the exception of inflammatory changes, typically associated with clefting of elastotic stroma. Clinical follow-up information was available for all patients and none developed subsequent evidence of a cutaneous or systemic vasculitis or neutrophilic dermatosis.
  
  
  
  Inflammatory changes appear to be more frequent in solar purpura than is generally recognised. Awareness of this histological variation and correlation with the clinical findings and evolution is important in avoiding misdiagnosis.
authors.affiliation: PathWest Laboratory Medicine, QEII Medical Center and Sir Charles Gairdner Hospital, the University of Western Australia, Perth, Western Australia, Australia.
authors.forename: Benjamin A
authors.initials: BA
authors.lastname: Wood
authors.forename: Philip E
authors.initials: PE
authors.lastname: LeBoit
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D006801:Humans; D015994:Incidence; D007249:Inflammation / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology*; D011693:Purpura / Q000145:classification* / Q000175:diagnosis* / Q000473:pathology; D012189:Retrospective Studies; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D016463:Sweet Syndrome / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology