title: An ultrasensitive electrochemical aptasensor with autonomous assembly of hemin-G-quadruplex DNAzyme nanowires for pseudo triple-enzyme cascade electrocatalytic amplification.
abstract: We for the first time fabricate a pseudo triple-enzyme cascade electrocatalytic electrochemical aptasensor by using the alcohol dehydrogenase (ADH) as well as the autonomously assembled hemin-G-quadruplex that simultaneously acted as an NADH oxidase and HRP-mimicking DNAzyme.
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
authors.forename: Yali
authors.initials: Y
authors.lastname: Yuan
authors.forename: Yaqin
authors.initials: Y
authors.lastname: Chai
authors.forename: Ruo
authors.initials: R
authors.lastname: Yuan
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhuo
authors.forename: Xianxue
authors.initials: X
authors.lastname: Gan
mesh_terms: D000426:Alcohol Dehydrogenase / Q000737:chemistry; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D002384:Catalysis; D021881:DNA, Catalytic / Q000737:chemistry*; D004563:Electrochemistry; D054856:G-Quadruplexes; D006427:Hemin / Q000737:chemistry*; D057230:Limit of Detection; D053770:Nanowires / Q000737:chemistry*
chemical_list: D052157:Aptamers, Nucleotide; D021881:DNA, Catalytic; D006427:Hemin; D000426:Alcohol Dehydrogenase