title: Giant petroclival endodermal cyst with xanthogranulomatous changes.
abstract: Endodermal cyst is a rare developmental cyst of the CNS, such as a Rathke cleft and colloid cyst lined by columnar epithelium of presumed endodermal origin. Intracranial endodermal cysts are rare, and most are found in the posterior fossa. The authors report a case of petroclival endodermal cyst with extensive bone destruction. A 12-year-old boy presented with transient facial weakness and headache. Imaging revealed a 3 × 3 × 4-cm, partial rim, enhanced cystic lesion in the petroclival area that was isointense on T1-weighted imaging and hyperintense in T2-weighted imaging. The cyst wall was partially removed and the cyst was obliterated using a lateral approach. Histological examination revealed ciliated, simple-to-pseudostratified cuboidal epithelium with a basement membrane that was consistent with an endodermal cyst, with the rare finding of xanthogranulomatous changes.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Ji Eun
authors.initials: JE
authors.lastname: Choi
authors.forename: Ho Jun
authors.initials: HJ
authors.lastname: Seol
authors.forename: Yang-Sun
authors.initials: YS
authors.lastname: Cho
mesh_terms: D020863:Central Nervous System Cysts / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D004707:Endoderm / Q000473:pathology*; D006801:Humans; D008297:Male; D010579:Petrous Bone / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014972:Xanthogranuloma, Juvenile / Q000175:diagnosis* / Q000473:pathology