title: CHD7 in charge of neurogenesis.
abstract: In this issue of Cell Stem Cell, Feng et al. (2013) report that the gene mutated in human CHARGE syndrome, ATP-dependent chromatin remodeling factor CHD7, contributes to the control of neurogenesis. The authors also report that exercise ameliorates these defects and suggest it as an intervention worthy of study in CHARGE syndrome.
authors.affiliation: Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
authors.forename: Kimberly H
authors.initials: KH
authors.lastname: Kim
authors.forename: Charles W M
authors.initials: CW
authors.lastname: Roberts
mesh_terms: D000818:Animals; D004268:DNA-Binding Proteins / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental; D058953:Neural Stem Cells / Q000166:cytology*; D055495:Neurogenesis / Q000502:physiology*; D055751:SOXC Transcription Factors / Q000378:metabolism*
chemical_list: C507367:Chd7 protein, mouse; D004268:DNA-Binding Proteins; D055751:SOXC Transcription Factors; C490793:Sox11 protein, mouse; C489990:Sox4 protein, mouse