title: Is routine bronchoscopic culture indicated in areas with low tuberculosis prevalence?
abstract: METHODS
  Tertiary care university-affiliated medical centre.
  
  
  OBJECTIVE
  To determine the value of routine culture of bronchoscopy samples for mycobacteria even when tuberculosis (TB) is not strongly suspected in low TB prevalence areas.
  
  
  METHODS
  A prospective study of 362 consecutive patients who underwent a bronchoscopy procedure. All demographic, clinical and computed tomography findings, and bacterial and mycobacterial culture results were collected.
  
  
  RESULTS
  A total of 217 men and 145 women, with a mean age of 63 ± 15 years, were included in the study. All underwent bronchoscopy with routine culture for TB. Ten cultures (2.8%) grew mycobacteria: 2 (0.55%) Mycobacterium tuberculosis and 8 (2.2%) non-tuberculous mycobacteria (NTM). The NTM included M. avium complex (MAC) in six patients and M. simiae in two patients. Two patients had two different mycobacteria species: 1 patient with M. simiae and MAC and the other with TB and MAC. All eight patients were negative for microscopy.
  
  
  CONCLUSIONS
  Based on our results, we suggest that routine culture of bronchial specimens for TB is not indicated in patients with a low clinical suspicion of active TB in countries with a low TB burden.
authors.affiliation: Pulmonary Department, Meir Medical Center, Kfar Saba, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: O
authors.initials: O
authors.lastname: Talker
authors.forename: A
authors.initials: A
authors.lastname: Matveychuk
authors.forename: A
authors.initials: A
authors.lastname: Guber
authors.forename: M M
authors.initials: MM
authors.lastname: Mandelbaum-Livnat
authors.forename: S
authors.initials: S
authors.lastname: Varsano
authors.forename: D
authors.initials: D
authors.lastname: Shitrit
mesh_terms: D000046:Academic Medical Centers; D000368:Aged; D001999:Bronchoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000453:epidemiology; D015269:Mycobacterium avium Complex / Q000302:isolation & purification; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis / Q000453:epidemiology; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D009170:Nontuberculous Mycobacteria / Q000302:isolation & purification; D015995:Prevalence; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed; D014376:Tuberculosis / Q000175:diagnosis* / Q000453:epidemiology