title: Closing in on a new treatment for sleeping sickness.
abstract: A chemoproteomics approach has been employed to identify a kinase that could be used as a druggable target in efforts to develop new treatments for African sleeping sickness.
authors.affiliation: is in the Department of Biological Chemistry and Molecular Pharmacology , Harvard Medical School , Boston , United States emily_derbyshire@hms.harvard.edu.
authors.forename: Emily R
authors.initials: ER
authors.lastname: Derbyshire
authors.forename: Jon
authors.initials: J
authors.lastname: Clardy
mesh_terms: D000981:Antiprotozoal Agents / Q000494:pharmacology*; D005658:Fungi / Q000378:metabolism*; D014346:Trypanosoma brucei brucei / Q000187:drug effects*; D015025:Zearalenone / Q000031:analogs & derivatives*
chemical_list: D000981:Antiprotozoal Agents; D015025:Zearalenone
keywords: Mouse; Other; T. brucei; chemical biology; chemoproteomics; hypothemycin; protein kinase