title: [Giant rhinoscleroma].
abstract: Rhinoscleroma is a chronic granulomatous respiratory tract disease. The initial lesion site is often intra-nasal. Giant tumor presentations are rare. The authors report a case of extensive nasal rhinoscleroma.
  
  
  METHODS
  A 35-year-old African male patient consulted for a large tumor of the nose. The tumor had appeared 25 years before; the initial lesion site was intra-nasal. It presented as a small non-obstructive growth. The tumor was removed 20 years before, and recurred in an exophytic presentation. The main tumor was associated to peripheral, peri-nasal, and upper lip nodules. There was a central granuloma, bleeding on contact. Nasal obstruction was complete. The histological and bacteriological examination of a biopsy specimen confirmed the diagnosis of rhinoscleroma. Trimethoprim-sulfamethoxazole was effective on the infection.
  
  
  CONCLUSIONS
  Rhinoscleroma is frequently located on the nasal mucosa, but extra-nasal giant tumor presentations are rare. It can involve the whole respiratory tract. It is endemic in developing countries. Sporadic cases have been described in non-endemic areas, among migrants. The diagnosis is proved by histology. Specific and early antibiotic therapy is effective. It avoids surgical mutilation, sequels, and recurrence.
authors.affiliation: Service de chirurgie plastique reconstructrice et esthétique, chirurgie de la main et brûlologie, CHU de Treichville, Abidjan 01, Côte-d'Ivoire. allahkchristophe@yahoo.fr
authors.forename: K C
authors.initials: KC
authors.lastname: Allah
authors.forename: H
authors.initials: H
authors.lastname: Kossoko
authors.forename: V
authors.initials: V
authors.lastname: Assi Djè Bi Djè
authors.forename: S
authors.initials: S
authors.lastname: Yéo
authors.forename: M
authors.initials: M
authors.lastname: Richard Kadio
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D018450:Disease Progression; D006801:Humans; D007710:Klebsiella Infections / Q000150:complications / Q000628:therapy; D007711:Klebsiella pneumoniae / Q000502:physiology; D008297:Male; D015508:Nasal Obstruction / Q000601:surgery; D009666:Nose / Q000601:surgery; D015366:Pefloxacin / Q000627:therapeutic use; D019651:Plastic Surgery Procedures; D012226:Rhinoscleroma / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000628:therapy; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D015366:Pefloxacin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination