title: [Analysis of the characteristics of toxins in 6005 cases of acute poisoning in Guangxi].
abstract: OBJECTIVE
  To investigate the toxin characteristics of toxins in patients of acute poisoning in the Guangxi area.
  
  
  METHODS
  A retrospective study was conducted. The data of acute poisoning cases and the causative toxins collected from 63 hospitals of Guangxi, including 36 city hospitals, 12 county hospitals, and 15 township health centers from January 2005 to December 2009 were collected. The data were descriptively analyzed and classified by year.
  
  
  RESULTS
  A total of 6005 cases with acute poisoning induced by 532 kinds of poisons were enrolled. The 532 kinds of toxin were classified by high-occurrence (producing poisoning for 5 continuous years), low-occurrence (leading to poisoning for 2-4 continuous years) and newly occurred categories (leading to poisoning only in 1 year). The numbers of poisons of these 3 categories accounted for 10.15% (54 kinds), 29.70% (158 kinds), 60.15% (320 kinds) of total number of poisons, respectively. There were 4688 (78.07%), 780 (12.99%), and 537 (8.94%) cases for each category respectively. And the poisoning cases of each toxin involved from 8 to 837, 2 to 25, and 1 to 69 cases respectively. 77.78% (42/54) of high-occurrence poisons affect more than 20 cases, and 89.87% (142/158), 98.75% (316/320) of low-occurrence and new-occurrence poisons involved less than 10 cases. In the dynamic analyses for 5 years, frequency of toxin caused by high-occurrence, low-occurrence and newly occurred poisons in 5 years were 5 times, 2.6 times, and 1 time, respectively. The number of poisons caused by the high-occurrence toxin each year were same, but the average-annual growth rates of poison numbers caused by the low-occurrence and new-occurrence poisons each year were 17.61% and 20.10%. The average-annual growth rates of poisoning cases caused by the 3 categories of poisons were 14.08%, 16.53%, 31.96%, and the average-annual growth rates of poisoning cases caused by each categories were 10.28%, 1.13%, 11.45%, respectively.
  
  
  CONCLUSIONS
  In the high-occurrence category, the poison species was least, the poisoning cases were most, the variety of the affected cases by each poison was largest, and the case involved by each toxin was increased by year. But in the newly occurred category, the poison constituent ratio was largest, but the poisoning population was the least, the disparity of each poison was least, and the toxin increased and the population affected each year were elevated. The characteristics of low-occurrence poison were between high-occurrence poison and newly occurred poison.
authors.affiliation: Guangxi Institute of Occupational Disease, Nanning 530021, Guangxi, China.
authors.forename: Dong-fang
authors.initials: DF
authors.lastname: Jiang
authors.forename: Zhen-ming
authors.initials: ZM
authors.lastname: Zhang
authors.forename: De-hong
authors.initials: DH
authors.lastname: Hu
authors.forename: Qing-hua
authors.initials: QH
authors.lastname: Liu
mesh_terms: D002681:China / Q000453:epidemiology; D006801:Humans; D011041:Poisoning / Q000453:epidemiology*; D011042:Poisons / Q000032:analysis* / Q000145:classification*; D012189:Retrospective Studies
chemical_list: D011042:Poisons