title: Can the spleen be divided into two functional parts?
abstract: Solid evidence has revealed unsuspected functions of the spleen. Asplenic or hyposplenic patients bear an increased susceptibility to overwhelming postsplenectomy infection. We, for the first time, performed the split splenic transplantation to redress hemophilia A. We also resected the middle part of the spleen completely and anatomically for the first time. Our findings illustrate that the spleen can be divided into 2 functional parts, and may shed a new light on the understanding and practice in splenic surgery.
authors.affiliation: Key Laboratory of Hepatosplenic Surgery, Department of General Surgery, The First Affiliated Hospital, Harbin Medical University, Harbin, China.
authors.forename: Hongchi
authors.initials: H
authors.lastname: Jiang
authors.forename: Lianxin
authors.initials: L
authors.lastname: Liu
authors.forename: Jizhou
authors.initials: J
authors.lastname: Wang
authors.forename: Haiquan
authors.initials: H
authors.lastname: Qiao
authors.forename: Zhaoyang
authors.initials: Z
authors.lastname: Lu
authors.forename: Xuan
authors.initials: X
authors.lastname: Song
mesh_terms: D000328:Adult; D005169:Factor VIII / Q000096:biosynthesis; D005260:Female; D006391:Hemangioma / Q000473:pathology / Q000601:surgery*; D006467:Hemophilia A / Q000097:blood / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D019520:Living Donors; D008297:Male; D013154:Spleen / Q000098:blood supply* / Q000378:metabolism / Q000637:transplantation*; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D007166:Immunosuppressive Agents; C078147:F8 protein, human; D005169:Factor VIII