title: Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology.
abstract: We developed a micromotor based miniature catheter with an outer diameter of 3.2 mm for ultrahigh speed endoscopic swept source optical coherence tomography (OCT) using a vertical cavity surface-emitting laser (VCSEL) at a 1 MHz axial scan rate. The micromotor can rotate a micro-prism at several hundred frames per second with less than 5 V drive voltage to provide fast and stable scanning, which is not sensitive to the bending of the catheter. The side-viewing probe can be pulled back to acquire a three-dimensional (3D) data set covering a large area on the specimen. The VCSEL provides a high axial scan rate to support dense sampling under high frame rate operation. Using a high speed data acquisition system, in vivo 3D-OCT imaging in the rabbit GI tract and ex vivo imaging of a human colon specimen with 8 μm axial resolution, 8 μm lateral resolution and 1.2 mm depth range in tissue at a frame rate of 400 fps was demonstrated.
authors.affiliation: Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
authors.forename: Tsung-Han
authors.initials: TH
authors.lastname: Tsai
authors.forename: Benjamin
authors.initials: B
authors.lastname: Potsaid
authors.forename: Yuankai K
authors.initials: YK
authors.lastname: Tao
authors.forename: Vijaysekhar
authors.initials: V
authors.lastname: Jayaraman
authors.forename: James
authors.initials: J
authors.lastname: Jiang
authors.forename: Peter J S
authors.initials: PJ
authors.lastname: Heim
authors.forename: Martin F
authors.initials: MF
authors.lastname: Kraus
authors.forename: Chao
authors.initials: C
authors.lastname: Zhou
authors.forename: Joachim
authors.initials: J
authors.lastname: Hornegger
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mashimo
authors.forename: Alex E
authors.initials: AE
authors.lastname: Cable
authors.forename: James G
authors.initials: JG
authors.lastname: Fujimoto
keywords: (110.2350) Fiber optics imaging; (120.3890) Medical optics instrumentation; (120.5800) Scanners; (140.3600) Three-dimensional image acquisition; (170.2150) Endoscopic imaging; (170.2680) Gastrointestinal; (170.3880) Medical and biological imaging; (170.4500) Optical coherence tomography