title: Doxorubicin-induced dilated cardiomyopathy for modified radical mastectomy: A case managed under cervical epidural anaesthesia.
abstract: Doxorubicin (Dox) is an antineoplastic agent used in a wide variety of malignancies. Its use is limited because of a cumulative, dose-dependent irreversible cardiomyopathy. We report a case of Dox induced cardiomyopathy, posted for modified radical mastectomy. The patient had poor LV function along with moderate pulmonary hypertension. Regional anaesthesia was planned as the risk associated with general anaesthesia was more. A cervical epidural was placed and a block adequate for surgery could be achived. The haemodynamic parameters as measured by esophageal doppler showed a stable trend. The surgery could be managed well under cervical epidural and also provided a good postoperative pain relief.
authors.affiliation: Department of Anaesthesiology, Sanjay Gandhi Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
authors.forename: Anuj
authors.initials: A
authors.lastname: Jain
authors.forename: Kamal
authors.initials: K
authors.lastname: Kishore
keywords: Adriamycin; cervical epidural; dilated cardiomyopathy; pulmonary arterial hypertension