title: Primary primitive neuroectodermal tumor of the cervix.
abstract: Primary primitive neuroectodermal tumors (PNETs) are rare and high-grade malignant tumors that mostly occur in children and young adults. The most common sites are the trunk, limbs, and retroperitoneum. Herein, we present a case of a PNET involving the cervix uteri in a 27-year-old woman. The lesion showed characteristic histologic features of a PNET and was positive for the immunohistochemical markers cluster of differentiation (CD) 99, vimentin, neuron-specific enolase, neural cell adhesion molecule 1 (CD56), and CD117 (c-kit), further defining the tumor while helping to confirm PNET. The clinical Stage IIIB tumor was treated with chemotherapy and radiotherapy.
authors.affiliation: Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, People's Republic of China.
authors.forename: Bo
authors.initials: B
authors.lastname: Li
authors.forename: Ling
authors.initials: L
authors.lastname: Ouyang
authors.forename: Xue
authors.initials: X
authors.lastname: Han
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhou
authors.forename: Xin
authors.initials: X
authors.lastname: Tong
authors.forename: Shulang
authors.initials: S
authors.lastname: Zhang
authors.forename: Qingfu
authors.initials: Q
authors.lastname: Zhang
keywords: PNET; cervical neoplasm; immunohistochemistry; primitive neuroectodermal tumor