title: A pictoral review on somatostatin receptor scintigraphy in neuroendocrine tumors: The role of multimodality imaging with SRS and GLUT receptor imaging with FDG PET-CT.
abstract: Somatostatin receptor scintigraphy is considered as a comprehensive imaging modality for many neuroendocrine tumors. Multiple radiotracers using combinations of gamma or positron emitting radionuclides and tracers are now available. Newer radiopharmaceuticals using (99m)Tc labeled with TOC, TATE, NOC are good alternatives to the 68 - Gallium radiotracers where the PET facility is not available. The pictoral depicts the role of SRS using 99m TC - HYNIC -TOC radiotracers in staging and treatment planning of NETs. Characterization of the tumor biology using combined SRS and FDG PET/CT is also demonstrated with a proposed categorization method. The emerging role of SRS in tailored targeted radionuclide therapy is outlined in brief.
authors.affiliation: Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Parel, Mumbai, India.
authors.forename: Sneha
authors.initials: S
authors.lastname: Shah
authors.forename: Nilendu
authors.initials: N
authors.lastname: Purandare
authors.forename: Archi
authors.initials: A
authors.lastname: Agrawal
authors.forename: Venkatesh
authors.initials: V
authors.lastname: Rangarajan
keywords: 99mTc HYNIC TOC; FDG PET/CT; neuroendocrine tumors; somatostatin receptor imaging