title: Are systemic lupus erythematosus patients carrying MEFV gene less prone to renal involvement? Report of three cases and review of the literature.
abstract: Familial Mediterranean fever (FMF) is an autosomal recessive auto inflammatory disease, characterized by acute attacks of serositis, arthritis or skin rash. Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease characterized by multisystem inflammatory lesions affecting any organ systems in the body. Coexistence of FMF and SLE is rare in literature. In this report, we present three patients with FMF associated with SLE.
authors.affiliation: Department of Rheumatology, Yıldırım Beyazıt University, Atatürk Education and Research Hospital, Ankara, Turkey. sukranerten@yahoo.com
authors.forename: Sukran
authors.initials: S
authors.lastname: Erten
authors.forename: Isilay
authors.initials: I
authors.lastname: Taskaldiran
authors.forename: Zeynep Ilerisoy
authors.initials: ZI
authors.lastname: Yakut
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D018501:Antirheumatic Agents / Q000008:administration & dosage; D003078:Colchicine / Q000008:administration & dosage; D003598:Cytoskeletal Proteins / Q000235:genetics*; D010505:Familial Mediterranean Fever / Q000150:complications / Q000188:drug therapy / Q000235:genetics / Q000503:physiopathology; D005260:Female; D006579:Heterozygote; D006801:Humans; D006886:Hydroxychloroquine / Q000008:administration & dosage; D007668:Kidney / Q000503:physiopathology*; D007677:Kidney Function Tests; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy / Q000235:genetics / Q000503:physiopathology; D008775:Methylprednisolone / Q000008:administration & dosage; D009154:Mutation; D062072:Patient Acuity; D000071198:Pyrin; D016896:Treatment Outcome; D050257:Tubulin Modulators / Q000008:administration & dosage
chemical_list: D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents; D003598:Cytoskeletal Proteins; C000604192:MEFV protein, human; D000071198:Pyrin; D050257:Tubulin Modulators; D006886:Hydroxychloroquine; D003078:Colchicine; D008775:Methylprednisolone