title: Comparative analysis of type of myocardial infarction in patients with successful or unsuccessful streptokinase thrombolysis following ST elevation myocardial infarction.
abstract: OBJECTIVE
  To study the effect of thrombolytic therapy in term of success and failure on the type of ST elevation MI, using streptokinase.
  
  
  METHODS
  This was a comparative study, conducted at Department of Cardiology, Lady Reading Hospital, Peshawar, from October 2006 to October 2007. Patients with first acute myocardial infarction were divided into group A (successful thrombolysis) and group B (unsuccessful thrombolysis) using ECG criteria.
  
  
  RESULTS
  Total number of patients were 200. Group A included 136 (68%) patients and group B included 64 (32%) patients. There were total 88 (44%) patients of anterior MI with 47 patients in group A and 41 patients in group B (34.6% vs 64.0%, p < 0.001). There were total 110 (55.0%) patients of inferior MI with 88 patients in group A and 22 patients in group B (64.7% vs 34.4%, p < 0.001). Lateral myocardial infarction was diagnosed in 2 (1%) patients with 1 patient each in group A and group B (0.7% vs 1.6%, p = 0.583).
  
  
  CONCLUSIONS
  Anterior MI was associated with a higher rate of thromblysis failure while inferior MI and lateral wall MI was associated with a higher rate of successful thrombolysis.
authors.affiliation: Department of Cardiology, Lady Reading Hospital Peshawar, Pakistan. docyousafzai@yahoo.com
authors.forename: Sher Bahadar
authors.initials: SB
authors.lastname: Khan
authors.lastname: Rafiullah
authors.forename: Lubna
authors.initials: L
authors.lastname: Noor
authors.forename: Khurshid
authors.initials: K
authors.lastname: Ahmad
authors.forename: Yasir
authors.initials: Y
authors.lastname: Adnan
authors.forename: Amber
authors.initials: A
authors.lastname: Ashraf
authors.forename: Asif
authors.initials: A
authors.lastname: Iqbal
authors.forename: Hafiz
authors.initials: H
authors.lastname: ur Rehman
authors.forename: Mohammad
authors.initials: M
authors.lastname: Hafizullah
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004562:Electrocardiography; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D013300:Streptokinase / Q000627:therapeutic use*; D015912:Thrombolytic Therapy; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D013300:Streptokinase