title: Sticky platelets syndrome in a young patient with massive pulmonary embolism.
abstract: METHODS
  Female, 51.
  
  
  METHODS
  Sticky platelets syndrome.
  
  
  METHODS
  Pulmonary embolism.
  
  
  METHODS
  -
  
  
  METHODS
  Thrombolysis.
  
  
  METHODS
  Hematology.
  
  
  OBJECTIVE
  Disease of unknown ethiology.
  
  
  BACKGROUND
  Sticky platelets syndrome (SPS) is an inherited thrombophilia characterized by platelet hyperaggregability, which can lead to the higher risk of thrombosis. The etiology of SPS remains unclear, but several gene polymorphisms have been recently studied and autosomal dominant heredity is suspected. Although SPS is traditionally connected with arterial thrombosis, several cases of SPS as a cause of venous thromboembolism have been described.
  
  
  METHODS
  We report the case of a 51-year-old apparently healthy woman with massive pulmonary embolism, who required thrombolytic therapy. In this patient SPS was identified as the only condition leading to higher risk of developing thromboembolic disease.
  
  
  CONCLUSIONS
  Although at present few physicians have practical experience with SPS, this syndrome may lead to serious health problems or even death. The presented case points to the benefit of SPS diagnostics in standard screening of inherited thrombophilia for effective prophylaxis and treatment in patients with venous thromboembolism.
authors.affiliation: Department of Internal Medicine I, Jessenius Faculty of Medicine, Comenius University, Martin, Slovak Republic.
authors.forename: Stanislava
authors.initials: S
authors.lastname: Darulová
authors.forename: Matej
authors.initials: M
authors.lastname: Samoš
authors.forename: Juraj
authors.initials: J
authors.lastname: Sokol
authors.forename: Radoslava
authors.initials: R
authors.lastname: Simonová
authors.forename: František
authors.initials: F
authors.lastname: Kovář
authors.forename: Peter
authors.initials: P
authors.lastname: Galajda
authors.forename: Ján
authors.initials: J
authors.lastname: Staško
authors.forename: Peter
authors.initials: P
authors.lastname: Kubisz
authors.forename: Marián
authors.initials: M
authors.lastname: Mokáň
keywords: inherited thrombophilia screening; sticky platelets syndrome; venous thromboembolism