title: Synthesis of (spiro)cyclopentapyridinones via C(sp3)-H functionalization: a post-Ugi gold-catalyzed regioselective tandem cyclization.
abstract: A gold-catalyzed regioselective tandem cyclization of N-propynylbutynamide via Csp(3)-H functionalization has been described, providing a distinctive methodology for the architecture of cyclopentapyridinones as well as spirocyclopentapyridinones.
authors.affiliation: Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, University of Leuven (KU Leuven), Celestijnenlaan 200F, B-3001, Leuven, Belgium.
authors.forename: Dipak D
authors.initials: DD
authors.lastname: Vachhani
authors.forename: Marzia
authors.initials: M
authors.lastname: Galli
authors.forename: Jeroen
authors.initials: J
authors.lastname: Jacobs
authors.forename: Luc
authors.initials: L
authors.lastname: Van Meervelt
authors.forename: Erik V
authors.initials: EV
authors.lastname: Van der Eycken
mesh_terms: D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D011728:Pyridones / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D011728:Pyridones; D013141:Spiro Compounds; D006046:Gold