title: Two Unique Cases with Anti-GluR Antibody-Positive Encephalitis.
abstract: We report two cases of anti-glutamic acid receptor (anti-GluR) antibody-positive encephalitis in males with symptoms such as Parkinsonism, urinary retention, and paralytic ileus. Although non-herpetic encephalitis typically shows magnetic resonance imaging (MRI) lesions in the limbic system during early stages, the present cases showed MRI lesions during later stages in the bilateral claustrum and pons. In both cases, anti-GluRɛ2 and δ2 antibodies were later shown to be positive in the cerebrospinal fluid but negative in the serum. Although early detection of anti-GluR antibodies is essential, early treatment may be significantly more important.
authors.affiliation: Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Matsuzono
authors.forename: Tomoko
authors.initials: T
authors.lastname: Kurata
authors.forename: Shoko
authors.initials: S
authors.lastname: Deguchi
authors.forename: Toru
authors.initials: T
authors.lastname: Yamashita
authors.forename: Kentaro
authors.initials: K
authors.lastname: Deguchi
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Ikeda
authors.forename: Koji
authors.initials: K
authors.lastname: Abe
keywords: MRI; Parkinsonism; anti-GluR antibody-positive encephalitis; autonomic failure