title: [Iodide mumps following low-osmolarity contrast medium use in haemodialysis patients].
abstract: Sialadenitis (Iodide Mumps) is a rare complication following the administration of iodinated contrast media. It is characterized by the painless bilateral enlargement of the submandibular salivary glands. The pathogenesis of this adverse reaction remains unclear. It may be due to an idiosyncratic reaction or related to toxic accumulation of iodide in the ductal systems of the salivary glands. Iodide mumps may occur after administration of any iodinated contrast agent: 98% of injected iodide is eliminated by the kidneys and only 2% is excreted from other organs such as salivary, sweat and lacrimal glands. Normally, the injected dose of contrast medium does not provide a sufficiently high iodide concentration to cause iodide mumps, but impaired renal excretion of contrast medium results in liberation of iodide and enables the salivary glands to concentrate inorganic iodide. This condition is rare and self-limiting. The current management is supportive therapy using analgesics and dialysis. We report two cases of iodide mumps in end-stage renal disease (ESRD) patients treated with haemodialysis after administration of iodinated contrast media. The cases were characterized by rapid onset and resolution of the symptoms in the absence of specific treatment.
authors.forename: Paola
authors.initials: P
authors.lastname: Nazzaro
authors.forename: Silvana
authors.initials: S
authors.lastname: Baranello
authors.forename: Marcellino
authors.initials: M
authors.lastname: Corvinelli
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Di Cienzo
authors.forename: Alba Maria Rita
authors.initials: AM
authors.lastname: Salvatore
authors.forename: Maurizio
authors.initials: M
authors.lastname: Brigante
mesh_terms: D003287:Contrast Media / Q000009:adverse effects*; D006801:Humans; D007454:Iodides / Q000009:adverse effects*; D007676:Kidney Failure, Chronic / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D012075:Remission, Spontaneous; D006435:Renal Dialysis; D012793:Sialadenitis / Q000139:chemically induced*
chemical_list: D003287:Contrast Media; D007454:Iodides