title: Hidden magicians of genome evolution.
abstract: Transposable elements (TEs) represent genome's dynamic component, causing mutations and genetic variations. Transposable elements can invade eukaryotic genomes in a short span; these are silenced by homology-dependent gene silencing and some functional parts of silenced elements are utilized to perform novel cellular functions. However, during the past two decades, major interest has been focused on the positive contribution of these elements in the evolution of genomes. The interaction between mobile DNAs and their host genomes are quite diverse, ranging from modifications of gene structure to alterations in general genome architecture and can be regarded as hidden magicians in shaping evolution of genomes. Some of the prominent examples that impressively demonstrate the beneficial impact of TEs on host biology over evolutionary time include their role in structure and functions of eukaryotic genomes.
authors.affiliation: Department of Genetics, Osmania University, Hyderabad, India.
authors.forename: C Sandeep
authors.initials: CS
authors.lastname: Kumar
authors.forename: Sameera Fatima
authors.initials: SF
authors.lastname: Qureshi
authors.forename: Altaf
authors.initials: A
authors.lastname: Ali
authors.forename: M L
authors.initials: ML
authors.lastname: Satyanarayana
authors.forename: Advithi
authors.initials: A
authors.lastname: Rangaraju
authors.forename: A
authors.initials: A
authors.lastname: Venkateshwari
authors.forename: Pratibha
authors.initials: P
authors.lastname: Nallari
mesh_terms: D000818:Animals; D002453:Cell Cycle; D004247:DNA / Q000235:genetics; D004251:DNA Transposable Elements / Q000235:genetics*; D004742:Enhancer Elements, Genetic; D019143:Evolution, Molecular; D020868:Gene Silencing; D022761:Gene Transfer, Horizontal; D016678:Genome; D015894:Genome, Human; D006801:Humans; D008957:Models, Genetic; D011401:Promoter Regions, Genetic; D020079:Terminal Repeat Sequences; D014158:Transcription, Genetic
chemical_list: D004251:DNA Transposable Elements; D004247:DNA