title: Unusual secondary metabolites from Astragalus halicacabus LAM.
abstract: From the whole plant of Astragalus halicacabus (Sect. Halicacabus), a new cycloartane-type glycoside, (20R,24S)-3-O-[α-L-arabinopyranosyl-(1→2)-β-D-xylopyranosyl]-20,24-epoxy-16-O-β-D-glucopyranosyl-3β,6α,16β,25-tetrahydroxycycloartane, and a new glycoside, 3-O-[β-D-apiofuranosyl-(1→2)-β-D-glucopyranosyl]maltol were isolated together with seven known cycloartane-type glycosides, i.e., cyclocanthoside D, askendosides D, F, and G, cyclosieversioside G, cyclostipuloside A, elongatoside, and a known maltol glucoside, 3-O-β-D-glucopyranosylmaltol. The structures were elucidated by means of high-resolution mass spectrometry, and extensive 1D- and 2D-NMR spectroscopic analysis. This is the first phytochemical work on A. halicacabus, and a maltol glycoside was encountered for the first time in the Leguminosae family.
authors.affiliation: Ege University, Faculty of Science, Department of Chemistry, Bornova, 35100, İzmir, Turkey.
authors.forename: Basile-Jimmy
authors.initials: BJ
authors.lastname: Djimtombaye
authors.forename: Özgen
authors.initials: Ö
authors.lastname: Alankuş-Çalışkan
authors.forename: Derya
authors.initials: D
authors.lastname: Gülcemal
authors.forename: Ikhlas A
authors.initials: IA
authors.lastname: Khan
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Anıl
authors.forename: Erdal
authors.initials: E
authors.lastname: Bedir
mesh_terms: D027883:Astragalus Plant / Q000737:chemistry / Q000378:metabolism*; D003512:Cyclohexanones / Q000737:chemistry* / Q000302:isolation & purification; D004187:Disaccharides / Q000737:chemistry* / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008968:Molecular Conformation; D014315:Triterpenes / Q000737:chemistry
chemical_list: D003512:Cyclohexanones; D004187:Disaccharides; D006027:Glycosides; D014315:Triterpenes; C085352:cycloartane
keywords: Astragalus halicacabus; Cycloartanes; Glycosides; Maltol glycosides