title: Introduction to autoinflammatory syndromes and diseases.
abstract: Autoinflammatory syndromes and diseases are a group of disorders of innate immunity. This group has grown rapidly in recent years as a result of research advancements in molecular biology and genetics. These diseases often present with skin manifestations and the dermatologist may not recognize the constellation of symptoms and medical history as a systemic inflammatory disease. Dermatologists would benefit from a deeper understanding of these diseases and the new treatments available for them.
authors.affiliation: Department of Medicine, Baylor University Medical Center and Texas A&M Medical School, 3500 Gaston Avenue, Dallas, TX 75246, USA. drA@dermcenter.us
authors.forename: William
authors.initials: W
authors.lastname: Abramovits
authors.forename: Marcial
authors.initials: M
authors.lastname: Oquendo
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D015551:Autoimmunity / Q000276:immunology; D001685:Biological Factors / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005260:Female; D056660:Hereditary Autoinflammatory Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology; D007249:Inflammation / Q000276:immunology; D007375:Interleukin-1 / Q000037:antagonists & inhibitors; D008297:Male; D012871:Skin Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D013577:Syndrome
chemical_list: D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D001685:Biological Factors; D007375:Interleukin-1
keywords: Autoinflammation; Familial Mediterranean fever; Inflammasome; Interleukins; Recurrent fever