title: Shigella takes the temperature.
abstract: For bacteria, temperature is a fairly reliable cue for entry into a vertebrate host. Many pathogenic bacteria sense elevated temperatures (37°C) and turn on virulence and metabolic genes appropriate for survival and growth within the host. A recent study demonstrated that the expression of a heme uptake protein in Shigella dysenteriae and pathogenic Escherichia coli was dependent on an RNA thermometer.
authors.affiliation: Veterinary Science and Microbiology; University of Arizona, Tucson, AZ, USA. vkv@email.arizona.edu
authors.forename: V K
authors.initials: VK
authors.lastname: Viswanathan
mesh_terms: D004926:Escherichia coli / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial / Q000235:genetics*; D006801:Humans; D007501:Iron / Q000378:metabolism*; D012329:RNA, Bacterial / Q000378:metabolism*; D012762:Shigella dysenteriae / Q000235:genetics*; D013696:Temperature
chemical_list: D012329:RNA, Bacterial; D007501:Iron
keywords: Listeria; PrfA; RNA thermometer; Shigella; ShuA; UPEC; heme; iron