title: Risk factors of liver failure after right-sided hepatectomy.
abstract: BACKGROUND
  To prevent hepatic failure after major hepatectomy, it is important to assess preoperative factors related to liver failure.
  
  
  METHODS
  We examined 80 patients who underwent right-sided hepatectomy. Hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay were defined as liver failure after hepatectomy, and these 3 factors were evaluated in relation to clinicopathological and surgical factors.
  
  
  RESULTS
  In the 80 patients, hyperbilirubinemia was observed in 10 (12.7%) patients, uncontrolled ascites in 18 (22.5%) patients, and prolonged hospital stay after surgery in 39 (48.8%) patients. Multivariate analyses identified platelet count as a risk factor of hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay, and the ratio of remnant liver volume to body surface area (RLV/BSA ratio) as an additional risk factor of hyperbilirubinemia and prolonged postoperative hospital stay.
  
  
  CONCLUSIONS
  Platelet count and RLV/BSA ratio are useful risk factors for prediction of liver failure after right-sided hepatectomy.
authors.affiliation: Department of Surgery I, Faculty of Medicine, Oita University, Hasama-machi, Yufu, Japan. teij03@oita-u.ac.jp
authors.forename: Teijiro
authors.initials: T
authors.lastname: Hirashita
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ohta
authors.forename: Yukio
authors.initials: Y
authors.lastname: Iwashita
authors.forename: Kentaro
authors.initials: K
authors.lastname: Iwaki
authors.forename: Hiroki
authors.initials: H
authors.lastname: Uchida
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yada
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Seigo
authors.initials: S
authors.lastname: Kitano
mesh_terms: D000368:Aged; D001201:Ascites / Q000453:epidemiology*; D005260:Female; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D006932:Hyperbilirubinemia / Q000453:epidemiology*; D007564:Japan / Q000453:epidemiology; D007902:Length of Stay / Q000706:statistics & numerical data; D008107:Liver Diseases / Q000601:surgery*; D017093:Liver Failure / Q000453:epidemiology*; D008297:Male; D009929:Organ Size; D010976:Platelet Count; D011183:Postoperative Complications / Q000453:epidemiology*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome
keywords: Hepatectomy; Liver failure; Major hepatectomy; Morbidity; Platelet count; Volumetry