title: Weight loss success in metabolic syndrome by telephone interventions: results from the SHINE Study.
abstract: BACKGROUND
  The Diabetes Prevention Program (DPP) intensive lifestyle intervention resulted in significant weight loss, reducing the development of diabetes, but needs to be adapted to primary care provider (PCP) practices.
  
  
  OBJECTIVE
  To compare a DPP-translation using individual (IC) vs. conference (CC) calls delivered by PCP staff for the outcome of percent weight loss over 2 years.
  
  
  METHODS
  Randomized clinical trial.
  
  
  METHODS
  Five PCP sites.
  
  
  METHODS
  Obese patients with metabolic syndrome, without diabetes (IC, n = 129; CC, n = 128).
  
  
  METHODS
  Telephone delivery of the DPP Lifestyle Balance intervention [16-session core curriculum in year 1, 12-session continued telephone contact in year 2 plus telephone coaching sessions (dietitians).
  
  
  METHODS
  Weight (kg), body mass index (BMI), and waist circumference.
  
  
  RESULTS
  
  
  
  METHODS
  age = 52 years, BMI = 39 kg/m(2), 75 % female, 85 % non-Hispanic White, 13 % non-Hispanic Black, and 48 % annual incomes <$40,000/year. In the intention-to-treat analyses at year 2, mean percent weight loss was -5.6 % (CC, p < 0.001) and -1.8 % (IC, p = 0.046) and was greater for CC than for IC (p = 0.016). At year 2, mean weight loss was 6.2 kg (CC) and 2.2 kg (IC) (p < 0.001). There was similar weight loss at year 1, but between year 1 and year 2 CC participants continued to lose while IC participants regained. At year 2, 52 % and 43 % (CC) and 29 % and 22 % (IC) of participants lost at least 5 % and 7 % of initial weight. BMI also decreased more for CC than IC (-2.1 kg/m(2) vs. -0.8 kg/m(2) p < 0.001). Waist circumference decreased by 3.1 cm (CC) and 2.4 cm (IC) at year 2. Completers (≥9 of 16 sessions; mean 13.3 sessions) lost significantly more weight than non-completers (mean 4.3 sessions).
  
  
  CONCLUSIONS
  PCP staff delivery of the DPP lifestyle intervention by telephone can be effective in achieving weight loss in obese people with metabolic syndrome. Greater weight loss may be attained with a group telephone intervention.
authors.affiliation: SUNY Upstate Medical University, 750 East Adams Street (CWB 353), Syracuse, NY, 13210, USA, weinstor@upstate.edu.
authors.forename: Ruth S
authors.initials: RS
authors.lastname: Weinstock
authors.forename: Paula M
authors.initials: PM
authors.lastname: Trief
authors.forename: Donald
authors.initials: D
authors.lastname: Cibula
authors.forename: Philip C
authors.initials: PC
authors.lastname: Morin
authors.forename: Linda M
authors.initials: LM
authors.lastname: Delahanty
mesh_terms: D000328:Adult; D000368:Aged; D061345:Early Medical Intervention / Q000379:methods*; D015444:Exercise / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D008875:Middle Aged; D015596:Nutrition Assessment; D009765:Obesity / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D040242:Risk Reduction Behavior; D013689:Telephone; D015431:Weight Loss / Q000502:physiology; D061217:Weight Reduction Programs / Q000379:methods*