title: [Lupus and pregnancy: study of 26 cases, an internal medicine department experience and review of the literature].
abstract: OBJECTIVE
  To study the maternal and fetal outcomes in women with systemic lupus erythematosus.
  
  
  METHODS
  A retrospective study of 26 pregnancies in 15 systemic erythematosus patients diagnosed before or during pregnancy regarding to American College of Rheumatology criteria in a single reference center.
  
  
  RESULTS
  The mean patient age was 31.52 years (24-39 years). The mean interval from the diagnosis of the systemic lupus erythematosus to pregnancy was 4.2 years. Eight pregnancies were planned. The flare rate of lupus during pregnancy was 31%, life birth rate was 65% and fetal loss rate was 35%.
  
  
  CONCLUSIONS
  As an increase in disease activity can occur during pregnancy and because of a higher rate of obstetrical complications in patients with lupus, it is important to carefully plan pregnancy. Pregnancy in lupus patients must be closely monitored by a multispeciality care of the patients.
authors.affiliation: Service de médecine interne B, CHU Charles-Nicolle, Tunis, Tunisie. Electronic address: syrinebellakhal@yahoo.fr.
authors.forename: S
authors.initials: S
authors.lastname: Bellakhal
authors.forename: L
authors.initials: L
authors.lastname: Ben Hassine
authors.forename: E
authors.initials: E
authors.lastname: Cherif
authors.forename: I
authors.initials: I
authors.lastname: Boukhris
authors.forename: S
authors.initials: S
authors.lastname: Azzabi
authors.forename: Z
authors.initials: Z
authors.lastname: Kaouache
authors.forename: C
authors.initials: C
authors.lastname: Kooli
authors.forename: N
authors.initials: N
authors.lastname: Khalfallah
mesh_terms: D000328:Adult; D005260:Female; D006748:Hospital Departments / Q000706:statistics & numerical data; D006801:Humans; D007231:Infant, Newborn; D007388:Internal Medicine; D050498:Live Birth / Q000453:epidemiology; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000453:epidemiology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000209:etiology; D011256:Pregnancy Outcome / Q000453:epidemiology*; D012189:Retrospective Studies; D055815:Young Adult
keywords: Complications de la grossesse; Grossesse; Lupus érythémateux systémique; Poussée de lupus érythémateux systémique; Pregnancy; Pregnancy complications; Systemic lupus erythematosus; Systemic lupus erythematosus flare