title: Three-dimensional magnetic resonance imaging using single breath-hold k-t BLAST for assessment of global left ventricular functional parameters.
abstract: OBJECTIVE
  To determine the accuracy of three-dimensional k-t broad-use linear acquisition speed-up technique (k-t BLAST) accelerated magnetic resonance imaging (MRI) for the assessment of left ventricular (LV) parameters compared to segmented multiple breath-hold cine imaging.
  
  
  METHODS
  A multislice cine (steady state free precession [SSFP]) sequence was performed with complete ventricular coverage during multiple breath-holds (temporal resolution 47 ms, voxel size 1.25 × 1.25 × 8 mm(3)). In addition, two k-t BLAST sequences with complete coverage were acquired, KT1 (temporal resolution 57 ms, voxel size 1.25 × 1.25 × 4 mm(3)) and k-t2 (temporal resolution 57 ms, voxel size 1.25 × 1.25 × 8 mm(3)), during a single breath-hold. For comparison of SSFP and k-t BLAST, LV parameters were determined: ejection fraction (EF), end-diastolic volume, end-systolic volume, and LV mass.
  
  
  RESULTS
  EF was underestimated by KT1 (47%) and KT2 (48%) compared to the SSFP sequence (53%). All parameters showed high correlation with the k-t BLAST sequences and the SSFP sequence (r = 0.88-0.98, P < .001). The mean relative difference for KT1/KT2 compared to the SSFP sequence was -0.11/-0.09 for the EF, -0.073/-0.086 for the EDV, 0.044/0.051 for the ESV, and 0.085/0.12 for the LV mass.
  
  
  CONCLUSIONS
  The use of three-dimensional k-t BLAST enabled a determination of the LV parameters with high correlation compared to the SSFP sequence. EF was slightly underestimated, and LV mass was slightly overestimated.
authors.affiliation: Department of Radiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany. jennifer.jaroni@web.de
authors.forename: Jennifer
authors.initials: J
authors.lastname: Jaroni
authors.forename: Reinhard
authors.initials: R
authors.lastname: Meier
authors.forename: Ambros
authors.initials: A
authors.lastname: Beer
authors.forename: Ken
authors.initials: K
authors.lastname: Herrmann
authors.forename: Marcus
authors.initials: M
authors.lastname: Settles
authors.forename: Ernst J
authors.initials: EJ
authors.lastname: Rummeny
authors.forename: Armin
authors.initials: A
authors.lastname: Huber
mesh_terms: D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D015656:Respiratory Mechanics; D012680:Sensitivity and Specificity; D013318:Stroke Volume; D018487:Ventricular Dysfunction, Left / Q000473:pathology*
keywords: Three-dimensional k-t BLAST; cardiac imaging; functional MRI; k-t BLAST