title: Real-time study of protein adsorption kinetics in porous silicon.
abstract: This paper presents an optical method for real-time monitoring of protein adsorption using porous silicon self-supported microcavities as a label-free detection platform. The study combines an experimental approach with a physical model for the adsorption process. The proposed model agrees well with experimental observations, and provides information about the kinetics of diffusion and adsorption of proteins within the pores, which will be useful for future experimental designs.
authors.affiliation: INTEC (UNL-CONICET), Güemes 3450, 3000 Santa Fe, Argentina. Electronic address: llasave@intec.unl.edu.ar.
authors.forename: Liliana C
authors.initials: LC
authors.lastname: Lasave
authors.affiliation: INTEC (UNL-CONICET), Güemes 3450, 3000 Santa Fe, Argentina; Facultad de Ingeniería Química (UNL), Santiago del Estero 2829, 3000 Santa Fe, Argentina.
authors.forename: Raúl
authors.initials: R
authors.lastname: Urteaga
authors.affiliation: INTEC (UNL-CONICET), Güemes 3450, 3000 Santa Fe, Argentina; Facultad de Ingeniería Química (UNL), Santiago del Estero 2829, 3000 Santa Fe, Argentina.
authors.forename: Roberto R
authors.initials: RR
authors.lastname: Koropecki
authors.affiliation: INTEC (UNL-CONICET), Güemes 3450, 3000 Santa Fe, Argentina.
authors.forename: Verónica D
authors.initials: VD
authors.lastname: Gonzalez
authors.affiliation: INTEC (UNL-CONICET), Güemes 3450, 3000 Santa Fe, Argentina.
authors.forename: Roberto D
authors.initials: RD
authors.lastname: Arce
mesh_terms: D000327:Adsorption; D003199:Computer Systems; D005949:Glucose Oxidase / Q000737:chemistry; D006735:Horseradish Peroxidase / Q000737:chemistry; D007700:Kinetics; D008958:Models, Molecular; D016062:Porosity; D011506:Proteins / Q000737:chemistry*; D012825:Silicon / Q000737:chemistry*
chemical_list: D011506:Proteins; D005949:Glucose Oxidase; D006735:Horseradish Peroxidase; D012825:Silicon
keywords: Kinetics; Porous silicon; Protein adsorption