title: HLA-G 5' URR SNPs and 3' UTR 14-bp insertion/deletion polymorphism in an Afro-Brazilian population from Paraná State.
abstract: The present study investigated 23 SNPs in the 5'URR promoter region and the 14 bp ins/del polymorphism at the 3'UTR region of the HLA-G gene in 150 individuals with Afro-Brazilian ancestry. Three haplotypes were found to be the most frequent. Comparing these polymorphisms in other samples, our data suggest that Afro-Brazilians are more similar to the Euro-Brazilians than to Hutterite population.
authors.affiliation: Department of Genetics, Laboratory of Immunogenetics and Histocompatibility, Universidade Federal do Paraná, Curitiba, Brazil.
authors.forename: L V
authors.initials: LV
authors.lastname: Tureck
authors.forename: L C
authors.initials: LC
authors.lastname: Santos
authors.forename: P F
authors.initials: PF
authors.lastname: Wowk
authors.forename: S B
authors.initials: SB
authors.lastname: Mattar
authors.forename: J S
authors.initials: JS
authors.lastname: Silva
authors.forename: J C M
authors.initials: JC
authors.lastname: Magalhães
authors.forename: V M M S
authors.initials: VM
authors.lastname: Roxo
authors.forename: M G
authors.initials: MG
authors.lastname: Bicalho
mesh_terms: D020413:3' Untranslated Regions; D020121:5' Untranslated Regions; D000483:Alleles; D001938:Brazil; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D005838:Genotype; D059951:HLA-G Antigens / Q000235:genetics*; D006239:Haplotypes; D006801:Humans; D054643:INDEL Mutation; D008297:Male; D020641:Polymorphism, Single Nucleotide
chemical_list: D020413:3' Untranslated Regions; D020121:5' Untranslated Regions; D059951:HLA-G Antigens