title: Neuropsychological functioning in adolescents with anorexia nervosa before and after cognitive remediation therapy: a feasibility trial.
abstract: OBJECTIVE
  To investigate neuropsychological functioning in adolescents with anorexia nervosa (AN) before and after receiving cognitive remediation therapy (CRT).
  
  
  METHODS
  Twenty young females with AN participated in an individually-delivered CRT treatment program. Neuropsychological and psychiatric assessments were administered before and after treatment. Weight, depression, anxiety, duration of illness, and level of eating disorder psychopathology were considered as covariates in statistical analyses.
  
  
  RESULTS
  Significant changes in weight, depression, visio-spatial memory, perceptual disembedding abilities, and verbal fluency were observed. Changes in weight had a significant effect on improvements in visuo-spatial memory and verbal fluency. Results also revealed a significant effect of depressive symptoms on perceptual disembedding abilities.
  
  
  CONCLUSIONS
  The results suggest improvements on a number of neuropsychological functions during the course of CRT. Future studies should explore the use of additional assessment instruments, and include control groups to assess the effectiveness of the intervention.
authors.affiliation: Division of Mental Health and Addiction, Regional Department for Eating Disorders, Oslo University Hospital Ullevål HF, Norway.
authors.forename: Camilla Lindvall
authors.initials: CL
authors.lastname: Dahlgren
authors.forename: Bryan
authors.initials: B
authors.lastname: Lask
authors.forename: Nils Inge
authors.initials: NI
authors.lastname: Landrø
authors.forename: Øyvind
authors.initials: Ø
authors.lastname: Rø
mesh_terms: D000293:Adolescent; D000856:Anorexia Nervosa / Q000523:psychology* / Q000628:therapy; D001835:Body Weight; D003072:Cognition Disorders / Q000150:complications / Q000628:therapy*; D015928:Cognitive Behavioral Therapy / Q000379:methods; D003863:Depression / Q000150:complications / Q000628:therapy; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D009483:Neuropsychological Tests
keywords: adolescents; anorexia nervosa; assessment; cognitive remediation therapy; neuropsychology