title: [Advances in the biochemical markers of complications associated with carotid endarterectomy].
abstract: Carotid endarterectomy(CEA)has been proved to be an effective surgery to treat the cerebral ischemia caused by carotid atherosclerotic stenosis. However,there is still no effective mean for the early diagnosis of the CEA-related severe complications such as stroke and death. Many studies have explored the potential biomarkers for stroke alert,although there is still a long way to go for their actual application in clinical settings. The carotid atherosclerotic stenosis,the perioperative complications of CEA,and the stroke share similar pathogenic mechanisms,and some biomarkers such as S100B,matrix metalloproteinase 9,asymmetric dimethylarginine,and neuron-specific enolase have been studied in the clinical trails of CEA. This article summarizes recent advances in this field.
authors.affiliation: Department of Vascular Surgery, PUMC Hospital, CAMS and PUMC, Beijing, China.
authors.forename: Li-fei
authors.initials: LF
authors.lastname: Wu
authors.forename: Zhi-cao
authors.initials: ZC
authors.lastname: Lai
authors.forename: Chang-wei
authors.initials: CW
authors.lastname: Liu
authors.forename: Tian-jia
authors.initials: TJ
authors.lastname: Li
authors.forename: Bao
authors.initials: B
authors.lastname: Liu
mesh_terms: D015415:Biomarkers / Q000378:metabolism*; D016894:Endarterectomy, Carotid; D006801:Humans; D007432:Intraoperative Period; D011183:Postoperative Complications / Q000517:prevention & control*; D018570:Risk Assessment; D064568:S100 Calcium Binding Protein beta Subunit / Q000378:metabolism
chemical_list: D015415:Biomarkers; D064568:S100 Calcium Binding Protein beta Subunit