title: [Changes parameters of humoral immunity in abdominal tuberculosis].
abstract: We measured the levels of IL-1beta, IL-8, and TNF-alpha, as well as humoral immunity in blood serum of patients with abdominal tuberculosis before and after Koch's test. The content of TNF-alpha increased 2.5 times, the content of IL-8 decreased almost twice, and concentration of IL-1beta decreased three times compared to the controls. We found that Koch's test exacerbates pathogenic manifestations of chronic inflammation which shows changes in cytokine spectrum of blood and allows us to refine diagnosis of abdominal tuberculosis.
authors.forename: N Ie
authors.initials: NIe
authors.lastname: Lapovets'
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D016207:Cytokines / Q000097:blood*; D005260:Female; D006801:Humans; D056724:Immunity, Humoral / Q000276:immunology*; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D014395:Peritonitis, Tuberculous / Q000097:blood / Q000175:diagnosis / Q000276:immunology*; D014374:Tuberculin Test; D055815:Young Adult
chemical_list: D016207:Cytokines; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M