title: Pancreatic cancer stem cells: their role in pancreatic cancer patient outcomes and what is future?
abstract: There is emerging evidence that stem cells might be playing an important role when it comes to cancer aggressiveness, metastasis, recurrence, resistance to chemotherapy and overall survival in hematologic malignancies as well as solid tumors including pancreatic adenocarcinoma. We review Abstract #e15058 presented at the 2013 ASCO Annual Meeting in Chicago by Andrikou et al.. Pancreatic cancer patients over-expressing pancreatic cancer stem cell markers were associated with aggressive tumors and worse survival.
authors.affiliation: Steward St. Elizabeth Medical Center, Tufts University School of Medicine. Boston, MA 02111, USA. dmhabib@gmail.com
authors.forename: Muzzamal
authors.initials: M
authors.lastname: Habib
authors.forename: Muhammad Wasif
authors.initials: MW
authors.lastname: Saif
mesh_terms: D000071916:AC133 Antigen; D000230:Adenocarcinoma / Q000378:metabolism / Q000473:pathology*; D015703:Antigens, CD / Q000378:metabolism; D014408:Biomarkers, Tumor / Q000378:metabolism; D006023:Glycoproteins / Q000378:metabolism; D006801:Humans; D018960:Hyaluronan Receptors / Q000378:metabolism; D014411:Neoplastic Stem Cells / Q000378:metabolism / Q000473:pathology*; D050814:Octamer Transcription Factor-3 / Q000378:metabolism; D010190:Pancreatic Neoplasms / Q000378:metabolism / Q000473:pathology*; D010455:Peptides / Q000378:metabolism; D011379:Prognosis; D016019:Survival Analysis
chemical_list: D000071916:AC133 Antigen; D015703:Antigens, CD; D014408:Biomarkers, Tumor; D006023:Glycoproteins; D018960:Hyaluronan Receptors; D050814:Octamer Transcription Factor-3; C494173:POU5F1 protein, human; D010455:Peptides