title: Predictive factors of open globe injury in patients requiring vitrectomy.
abstract: BACKGROUND
  To determine the outcomes and predictive factors of patients with open globe injury requiring pars plana vitrectomy (PPV).
  
  
  METHODS
  The medical records of 114 patients age 10 years or older who had undergone PPV due to ocular trauma, with at least 6 months follow up, were retrospectively reviewed.
  
  
  RESULTS
  The mean age of the patients was 42 (SD14) years, with males accounting for 89% of the cases. Penetrating eye injury was the most common injury mechanism (43%) with most injuries occurring secondary to work related incidents (54%). After surgical interventions, 78% of the patients had visual improvement of one or more Snellen lines, while no light perception occurred in 10%. Anatomical attachment was achieved in 87% of eyes at the final follow up. Logistic regression analysis showed that the presence of a relative afferent pupillary defect (RAPD) was a significant predictive factor of visual outcome, while initial retinal detachment was a significant predictor of anatomical outcome.
  
  
  CONCLUSIONS
  Pupillary reaction is an important presenting ocular sign in estimating the post-vitrectomy poor visual outcome for open globe injury. Vision was restored and improved in more than half of the patients in this study; however, long-term sequelae should be monitored.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Thailand.
authors.forename: Weeraya
authors.initials: W
authors.lastname: Pimolrat
authors.forename: Janejit
authors.initials: J
authors.lastname: Choovuthayakorn
authors.forename: Nawat
authors.initials: N
authors.lastname: Watanachai
authors.forename: Direk
authors.initials: D
authors.lastname: Patikulsila
authors.forename: Paradee
authors.initials: P
authors.lastname: Kunavisarut
authors.forename: Voraporn
authors.initials: V
authors.lastname: Chaikitmongkol
authors.forename: Nimitr
authors.initials: N
authors.lastname: Ittipunkul
mesh_terms: D000328:Adult; D005131:Eye Injuries / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery*; D015807:Eye Injuries, Penetrating / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D011237:Predictive Value of Tests; D011379:Prognosis; D011680:Pupil; D012163:Retinal Detachment / Q000517:prevention & control*; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*
keywords: Open globe injury; Prognosis; Trauma; Vitrectomy; Vitreoretinal surgery