title: Myofibroma of the tongue: a case suggesting autosomal dominant inheritance.
abstract: Myofibroma and myofibromatosis are rare, benign mesenchymal neoplasms composed of spindle-shaped contractile myoid cells and myofibroblasts, which generally develop in infancy or before the age of 2 years. At present, the precise etiology of this condition is unknown, with most cases reported as sporadic. However, some cases have suggested the possibility of a familial pattern of inheritance, with both dominant and -recessive patterns of inheritance have been reported. Presented here is a case of myofibroma associated with a family history of myofibromatosis, suggesting autosomal-dominant inheritance.
authors.affiliation: Assistant Professor, Department of Regenerative Oral Surgery, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. Electronic address: n-tajima@nagasaki-u.ac.jp.
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Tajima
authors.affiliation: Assistant Professor, Department of Regenerative Oral Surgery, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shiraishi
authors.affiliation: Lecturer, Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences, University of Fukui, Eiheiji-cho, Japan.
authors.forename: Seigo
authors.initials: S
authors.lastname: Ohba
authors.affiliation: Associate Professor, Department of Oral Pathology and Bone Metabolism, Unit of Basic Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Fujita
authors.affiliation: Professor, Department of Regenerative Oral Surgery, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors.forename: Izumi
authors.initials: I
authors.lastname: Asahina
mesh_terms: D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D020022:Genetic Predisposition to Disease; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D047708:Myofibroma / Q000175:diagnosis* / Q000235:genetics* / Q000473:pathology; D014062:Tongue Neoplasms / Q000175:diagnosis* / Q000235:genetics* / Q000473:pathology