title: LDK378: a promising anaplastic lymphoma kinase (ALK) inhibitor.
authors.affiliation: Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, University of Michigan , Ann Arbor, Michigan 48109, United States.
authors.forename: Jianyong
authors.initials: J
authors.lastname: Chen
authors.forename: Cheng
authors.initials: C
authors.lastname: Jiang
authors.forename: Shaomeng
authors.initials: S
authors.lastname: Wang
mesh_terms: D000077548:Anaplastic Lymphoma Kinase; D000818:Animals; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000188:drug therapy*; D047428:Protein Kinase Inhibitors / Q000138:chemical synthesis*; D011743:Pyrimidines / Q000138:chemical synthesis*; D020794:Receptor Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors*; D013450:Sulfones / Q000138:chemical synthesis*
chemical_list: D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D013450:Sulfones; C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases; C586847:ceritinib