title: Nine-year follow-up of local implantation of autologous skeletal myoblasts in a patient with coronary heart disease.
abstract: METHODS
  gender - Male, age - 63 year-old.
  Acute myocardial infarction.
  Hypertension.
  
  
  METHODS
  Aspirin • beta-blocker • captopril.
  
  
  METHODS
  CABG • autologous skeletal myoblast transplantation • PCI.
  
  
  METHODS
  Cardiology.
  
  
  OBJECTIVE
  Unusual or unexpected effect of treatment.
  
  
  BACKGROUND
  Cell transplantation has been viewed as a promising strategy for end-stage heart failure, but long-term follow-up results are lacking.
  
  
  METHODS
  In December 2002 we began transplanting autologous skeletal myoblasts in one patient because of serious coronary heart disease. Here, we present the 9-year follow-up results of this patient. No ventricular tachyarrhythmias were detected after treatment. The patient had another myocardial infarction in April 2012 and was treated successful with PCI.
  
  
  CONCLUSIONS
  Autologous skeletal myoblast transplantation with bypass surgery is associated with improvement in cardiac function and lack of adverse effects in long-term follow-up, making it a promising therapy for patients with heart failure.
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China.
authors.forename: Dingguo
authors.initials: D
authors.lastname: Zhang
authors.forename: Liansheng
authors.initials: L
authors.lastname: Wang
authors.forename: Fumin
authors.initials: F
authors.lastname: Zhang
authors.forename: Chunjian
authors.initials: C
authors.lastname: Li
authors.forename: Tiebing
authors.initials: T
authors.lastname: Zhu
authors.forename: Kejiang
authors.initials: K
authors.lastname: Cao
authors.forename: Wenzhu
authors.initials: W
authors.lastname: Ma
authors.forename: Zhijian
authors.initials: Z
authors.lastname: Yang
keywords: cellular transplantation; heart failure; ischemic heart disease; skeletal myoblast