title: Comparative study of antibacterial and antifungal effects of rigid gas permeable contact lens disinfecting solutions.
abstract: The aim of this study was to compare antimicrobial efficacy of rigid contact lens disinfecting solutions. We tested five commercially available solutions: Unique pH (Alcon Laboratories), Boston Advance (Polymer Technology Corp.), Nitilens Conditioner GP (Avizor), Total Care (AMO), Boston Simplus (Bausch&Lomb). Their efficacy to disinfect saline solution experimentally contaminated with American Type Culture Collection (ATCC): Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans (ATCC 90028) and Staphylococcus epidermidis (isolated from our laboratory) was tested. All tested solutions reduced concentrations of bacteria and fungi below 1000 CFU/mL (Colony forming unit; reduction by 3 log and 1 log, respectively) after the 8 hours period. Overall, all contact lens care solutions showed good disinfecting activity against tested bacteria and fungi, with more variation in their antifungal than in antibacterial efficacy. Results of our study might be valuable when selecting appropriate solutions for non-compliant contact lens wearers.
authors.affiliation: University of Zagreb, Zagreb University Hospital Centre, Department of Ophthalmology, Zagreb, Croatia. tomislav.kuzman@kbc-zagreb.hr
authors.forename: Tomislav
authors.initials: T
authors.lastname: Kuzman
authors.forename: Marija Barisić
authors.initials: MB
authors.lastname: Kutija
authors.forename: Rajko
authors.initials: R
authors.lastname: Kordić
authors.forename: Smiljka
authors.initials: S
authors.lastname: Popović-Sui
authors.forename: Sonja
authors.initials: S
authors.lastname: Jandroković
authors.forename: Ivan
authors.initials: I
authors.lastname: Skegro
authors.forename: Rajko
authors.initials: R
authors.lastname: Pokupec
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D018639:Contact Lens Solutions / Q000494:pharmacology*; D003261:Contact Lenses
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D018639:Contact Lens Solutions