title: Antibacterial activity of a 7,10-dihydroxy-8(E)-octadecenoic acid against plant pathogenic bacteria.
abstract: 7,10-Dihydroxy-8(E)-octadecenoic acid (DOD), one of hydroxy fatty acids, was successfully produced from oleic acid and natural vegetable oils containing oleic acid by a bacterial strain Pseudomonas aeruginosa (PR3). However, biological properties of DOD remained unknown so far. In this study, as a trial to determine the biological properties of DOD molecule, antibacterial activities of DOD against plant pathogenic bacteria were determined qualitatively and quantitatively. DOD presented strong antibacterial activities against all the bacterial strains tested with MIC value being in the range of 125-1000μg/ml and there was no sensitivity preference detected between Gram-positive and Gram-negative strains.
authors.affiliation: School of Food Science and Biotechnology, Kyungpook National University, Daegu 702-701, Republic of Korea.
authors.forename: Hye-Ran
authors.initials: HR
authors.lastname: Sohn
authors.forename: Jae-Han
authors.initials: JH
authors.lastname: Bae
authors.forename: Ching T
authors.initials: CT
authors.lastname: Hou
authors.forename: Hak-Ryul
authors.initials: HR
authors.lastname: Kim
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000472:pathogenicity; D001709:Biotechnology; D048230:Corynebacterium glutamicum / Q000187:drug effects / Q000472:pathogenicity; D052978:Disk Diffusion Antimicrobial Tests; D004885:Erwinia / Q000187:drug effects / Q000472:pathogenicity; D008826:Microbial Sensitivity Tests; D019301:Oleic Acid / Q000378:metabolism; D009829:Oleic Acids / Q000096:biosynthesis / Q000494:pharmacology*; D010944:Plants / Q000382:microbiology*; D011549:Pseudomonas / Q000187:drug effects / Q000472:pathogenicity; D011550:Pseudomonas aeruginosa / Q000378:metabolism; D044224:Pseudomonas syringae / Q000187:drug effects / Q000472:pathogenicity; D043368:Ralstonia solanacearum / Q000187:drug effects / Q000472:pathogenicity; D013045:Species Specificity
chemical_list: C477043:7,10-dihydroxy-8-octadecenoic acid; D000900:Anti-Bacterial Agents; D009829:Oleic Acids; D019301:Oleic Acid
keywords: 7,10-Dihydroxy-8(E)-octadecenoic acid; Antibacterial activity; Bioconversion; Plant pathogenic bacteria; Pseudomonas aeruginosa; Vegetable oil