title: Clinico-pathological profile of sinonasal masses: An experience in tertiary care hospital of Uttarakhand.
abstract: BACKGROUND
  The purpose of this study was to classify various types of non-neoplastic and neoplastic lesions presenting as sinonasal mass and characterize their clinico-pathological profile in a tertiary care center in the state of Uttarakhand.
  
  
  METHODS
  This was a prospective study where 110 cases of sinonasal masses were included over a period of 12 months. Clinico-pathological study was carried out in these cases. A provisional diagnosis was made after clinical assessment and radiologic investigations, but final diagnosis was made after histopathologic examination.
  
  
  METHODS
  The number of non-neoplastic lesions were more than the neoplastic lesion, 60% versus 40% respectively. In the neoplastic group, 19.8% and 23.76% patients presented with benign and malignant lesion, respectively. The incidence was more predominant in the age group of 11-20 years (22.72%) with male to female ratio of 1.08:1. In our study, among non-neoplastic lesions the occurrence of sinonasal polyps was highest seen in 80.30% cases. In neoplastic lesions, angiofibroma was most common benign lesion seen in 35% cases. Carcinoma nasal cavity was the commonest malignant lesion seen in 45.83% cases. In 3.63% patients, clinical and radiologic diagnosis was not correlated with histopathologic diagnosis. Only two cases required immuno-histocytochemistry to confirm the final diagnosis.
  
  
  CONCLUSIONS
  We concluded that for proper evaluation of a sinonasal mass, clinical, radiologic, and histopathologic evaluation should be carried out conjointly in all the cases. Histopathology always gives a confirmatory diagnosis but in few cases immuno-histocytochemistry becomes the ultimate diagnostic technique for correct and timely intervention.
authors.affiliation: Department of E.N.T and Head Neck Surgery, Himalayan Institute of Medical Sciences, H.I.H.T. University, Jolly Grant, Doiwala, Dehradun, Uttarakhand, India.
authors.forename: S S
authors.initials: SS
authors.lastname: Bist
authors.forename: Saurabh
authors.initials: S
authors.lastname: Varshney
authors.forename: Vijay
authors.initials: V
authors.lastname: Baunthiyal
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Bhagat
authors.forename: Anuradha
authors.initials: A
authors.lastname: Kusum
keywords: Histopathology; neoplastic lesion; sinonasal mass