title: [Analysis on status and characteristics of laboratory-acquired vaccinia virus infections cases].
abstract: OBJECTIVE
  By analyzing the status and characteristics of vaccinia virus laboratory-acquired infections in the bibliographical information, this paper provides relevant recommendations and measures for prevention and control of vaccinia virus laboratory-acquired infections in China.
  
  
  METHODS
  Choosing PubMed, Embase, Biosis and SCIE, SSCI, CPCI-S as well as CPCI-SSH covered by Web of Science as the data source, indexing the bibliography of vaccinia virus laboratory-acquired infections, this paper analyzes the information on whether to vaccinate, the occurrence time of symptoms, diseasedparts, symptom characteristics and the disease-causing reasons.
  
  
  RESULTS
  The outcome shows that 52. 9% of the cases never get vaccinated, 82.4% engaged in vaccinia virus related researches never get vaccinated in 10 years, 52. 9% get infected by the accidental needlestick in hands during the process of handling animal experiments, 70. 6% of infections occur in the hands and having symptoms after being exposed with an average of 5. 1 days.
  
  
  CONCLUSIONS
  Although it is still controversial that whether or not to be vaccinated before carrying out vaccinia virus related works, it should be important aspects of prevention and control of vaccinia virus laboratory-acquired infections with the strict compliance with the operating requirements of the biosafety, by strengthening personal protection and timely taking emergency measures when unforeseen circumstances occur, as well as providing the research background information to doctors.
authors.affiliation: Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wei
authors.forename: Xuan-cheng
authors.initials: XC
authors.lastname: Lu
authors.forename: Gui-zhen
authors.initials: GZ
authors.lastname: Wu
mesh_terms: D002681:China; D006801:Humans; D007757:Laboratory Infection / Q000517:prevention & control* / Q000635:transmission / Q000821:virology*; D016602:Needlestick Injuries / Q000821:virology; D016273:Occupational Exposure / Q000009:adverse effects*; D014615:Vaccinia / Q000209:etiology* / Q000517:prevention & control* / Q000635:transmission / Q000821:virology; D014616:Vaccinia virus