title: On-pump versus off-pump coronary artery bypass surgery: what is the status after ROOBY, DOORS, CORONARY and GOPCABE?
abstract: Off-pump coronary artery bypass surgery has been purported to be safer than conventional coronary artery bypass surgery performed using cardiopulmonary bypass. This theory was supported by a number of early series, but failed to be confirmed by a number of small, randomized, controlled trials. Conversely, it has been suggested that revascularization after off-pump surgery is associated with fewer grafts and lower graft patency, potentially leading to a higher risk of cardiovascular morbidity and need for repeated coronary interventions. Since 2009, four major randomized controlled trials have been published, increasing the level of evidence significantly.
authors.affiliation: Department of Vascular Surgery, Kolding Hospital, Skovvangen 6-8, 6000 Kolding, Denmark. kim.christian.houlind@slb.regionsyddanmark.dk
authors.forename: Kim
authors.initials: K
authors.lastname: Houlind
mesh_terms: D001026:Coronary Artery Bypass / Q000379:methods*; D047549:Coronary Artery Bypass, Off-Pump / Q000379:methods; D006801:Humans; D017202:Myocardial Ischemia / Q000601:surgery*; D055502:Secondary Prevention; D016896:Treatment Outcome