title: Gorlos-Phos: addressing the stereoselectivity in palladium-catalyzed exo-mode cyclization of allenes with a nucleophilic functionality.
abstract: A novel catalyst system has been indentified for addressing the long-standing issue of Z/E stereoselectivity in palladium-catalyzed exo-mode cyclization reactions of allenes bearing a nucleophilic functionality with organic halides or their equivalents. The readily accessible, sterically hindered monophosphine ligand Gorlos-Phos·HBF4 imparts a remarkable stereocontrolling ability with broad generality under Pd catalysis.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, PR China.
authors.forename: Juntao
authors.initials: J
authors.lastname: Ye
authors.forename: Suhua
authors.initials: S
authors.lastname: Li
authors.forename: Shengming
authors.initials: S
authors.lastname: Ma