title: RACER: Rapid and accurate correction of errors in reads.
abstract: BACKGROUND
  High-throughput next-generation sequencing technologies enable increasingly fast and affordable sequencing of genomes and transcriptomes, with a broad range of applications. The quality of the sequencing data is crucial for all applications. A significant portion of the data produced contains errors, and ever more efficient error correction programs are needed.
  
  
  RESULTS
  We propose RACER (Rapid and Accurate Correction of Errors in Reads), a new software program for correcting errors in sequencing data. RACER has better error-correcting performance than existing programs, is faster and requires less memory. To support our claims, we performed extensive comparison with the existing leading programs on a variety of real datasets.
  
  
  BACKGROUND
  RACER is freely available for non-commercial use at www.csd.uwo.ca/∼ilie/RACER/.
authors.affiliation: Department of Computer Science, University of Western Ontario, N6A 5B7 London, ON, Canada.
authors.forename: Lucian
authors.initials: L
authors.lastname: Ilie
authors.forename: Michael
authors.initials: M
authors.lastname: Molnar
mesh_terms: D000818:Animals; D016678:Genome; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D013997:Time Factors