title: Graphics processing unit accelerated intensity-based optical coherence tomography angiography using differential frames with real-time motion correction.
abstract: We demonstrate intensity-based optical coherence tomography (OCT) angiography using the squared difference of two sequential frames with bulk-tissue-motion (BTM) correction. This motion correction was performed by minimization of the sum of the pixel values using axial- and lateral-pixel-shifted structural OCT images. We extract the BTM-corrected image from a total of 25 calculated OCT angiographic images. Image processing was accelerated by a graphics processing unit (GPU) with many stream processors to optimize the parallel processing procedure. The GPU processing rate was faster than that of a line scan camera (46.9 kHz). Our OCT system provides the means of displaying structural OCT images and BTM-corrected OCT angiographic images in real time.
authors.affiliation: Yamagata University, Bio-systems Engineering, Graduate School of Science and Engineering, 4-3-16 Johnan, Yonezawa, Yamagata 992-8510, Japan. ywata@yz.yamagata-u.ac.jp
authors.forename: Yuuki
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Yuhei
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Numazawa
mesh_terms: D000792:Angiography / Q000295:instrumentation / Q000379:methods*; D003196:Computer Graphics; D003199:Computer Systems; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D009038:Motion; D009262:Nails / Q000098:blood supply; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*