title: Effects of silicone hydrogel contact lenses on ocular surface after Sub-Bowman's Keratomileusis.
abstract: OBJECTIVE
  To evaluate the efficacy of silicone hydrogel contact lenses on ocular surface after Sub-Bowman Keratomileusis (SBK).
  
  
  METHODS
  Forty-six patients suffered from myopia underwent a bilateral SBK. Post-operatively, one eye of each patient wore a PureVision contact lens for 24 h as a treated eye and the contralateral eye was as a blank control. Afterwards, corneal fluorescein (FL) staining, tear break-up time (TBUT), schirmer I test (SIT), central corneal thickness (CCT), ocular surface disease index (OSDI), corneal hysteresis (CH), corneal resistance factor (CRF) and corneal flap complications were assessed 1 d (except for CH and CRF), 1 week, 1 month and 3 months postoperatively.
  
  
  RESULTS
  Following SBK, in contrast to the control, corneal fluorescein staining of treated eyes were significantly reduced and tear break-up time of treated eyes were significantly improved at 1 d and 1 week after SBK. However, Schirmer I test of treated and control eyes were not different after SBK. Central corneal thickness of treated eyes were significantly thinner than that of control at 1 d after SBK, however, there were no differences at other time points. Ocular surface disease index of treated eyes were obviously alleviated more than that of control at 1 d after SBK, but no differences were found at other visits. Moreover, Corneal hysteresis and corneal resistance factor of treated and un-treated eyes were not different after surgery. And also the rate of corneal flap complications were not different between treated and control eyes after SBK.
  
  
  CONCLUSIONS
  Silicone hydrogel contact lenses played a positive role in accelerating corneal epithelial healing, enhancing tear film stability and reducing discomfort of patients in the early stage after SBK.
authors.affiliation: Zhongshan Ophthalmic Center and State Key Laboratory of Ophthalmology, Hainan Eye Hospital, Sun Yat-sen University , Guangzhou , China.
authors.forename: Shaohui
authors.initials: S
authors.lastname: Gao
authors.forename: Junshu
authors.initials: J
authors.lastname: Wu
authors.forename: Lili
authors.initials: L
authors.lastname: Li
authors.forename: Yong
authors.initials: Y
authors.lastname: Wang
authors.forename: Xingwu
authors.initials: X
authors.lastname: Zhong
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D003263:Contact Lenses, Hydrophilic; D019573:Epithelium, Corneal / Q000502:physiology / Q000601:surgery; D005260:Female; D019793:Fluorescein; D005456:Fluorescent Dyes; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D008297:Male; D009216:Myopia / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D012828:Silicones; D013524:Surgical Flaps; D016896:Treatment Outcome; D014945:Wound Healing; D055815:Young Adult
chemical_list: D005456:Fluorescent Dyes; D012828:Silicones; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D019793:Fluorescein