title: Gastrointestinal stromal tumors (GIST): lesser known facts.
abstract: In an era of molecular targeted therapy, patients with advanced gastrointestinal stromal tumor (GIST) are living longer and are often followed with imaging. Therefore, it is important for the radiologists to be aware of the atypical subtypes of GIST, implications of molecular makeup, its behavior, and the uncommon metastatic sites. The aim of this pictorial review is to illustrate the lesser-known aspects of GIST including histological and molecular classifications, syndromes associated with GIST, and uncommon metastatic sites.
authors.affiliation: Department of Radiology, Cork University Hospital, Wilton, Cork, Ireland.
authors.forename: Kevin N
authors.initials: KN
authors.lastname: O'Regan
authors.forename: Atul B
authors.initials: AB
authors.lastname: Shinagare
authors.forename: Sachin S
authors.initials: SS
authors.lastname: Saboo
authors.forename: Nikhil H
authors.initials: NH
authors.lastname: Ramaiya
authors.forename: Jyothi P
authors.initials: JP
authors.lastname: Jagannathan
authors.forename: Sree Harsha
authors.initials: SH
authors.lastname: Tirumani
mesh_terms: D000328:Adult; D056733:Carney Complex / Q000145:classification / Q000188:drug therapy / Q000473:pathology; D002648:Child; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000145:classification* / Q000188:drug therapy / Q000473:pathology; D046152:Gastrointestinal Stromal Tumors / Q000145:classification* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008297:Male; D058990:Molecular Targeted Therapy; D009456:Neurofibromatosis 1 / Q000145:classification / Q000188:drug therapy / Q000473:pathology
keywords: Atypical metastases; Gastrointestinal stromal tumor; Molecular classification; Syndromes associated with GIST; Tumor biology