title: Severe eyelid oedema in Graves' ophthalmopathy.
abstract: We report a case of severe eyelid oedema due to Graves' ophthalmopathy (GO). The aim was to present a case report and review of the literature about eyelid oedema due to GO. The case report includes a history of patient data and literature review. The patient was offered intravenous methylprednisolone and gave consent. A dosage of 500 mg intravenous methylprednisolone once weekly for 6 weeks, followed by 250 mg intravenous methylprednisolone once weekly for 6 weeks, with a total treatment period of 12 weeks was given. Up to day, minor improvement has been observed. Severe eyelid oedema due to GO is a rare manifestation of Graves' disease. In cases of active and moderate-to-severe disease, treatment with intravenous glucorticoids is recommended alone or with orbital radiotherapy, followed by rehabilitative surgery.
authors.affiliation: Endocrinology-Diabetes Department, Hippokration Hospital, Thessaloniki, Greece.
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Anagnostis
authors.forename: Fotini
authors.initials: F
authors.lastname: Adamidou
authors.forename: Maria
authors.initials: M
authors.lastname: Poulasouchidou
authors.forename: Spyridon
authors.initials: S
authors.lastname: Karras
mesh_terms: D004487:Edema / Q000188:drug therapy / Q000209:etiology*; D005141:Eyelid Diseases / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D049970:Graves Ophthalmopathy / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D012720:Severity of Illness Index
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone