title: The challenge of prognostic markers in pleural mesothelioma.
abstract: Malignant pleural mesothelioma (MPM) is a very aggressive tumor, highly resistant to chemo- and radio-therapy. Treatment of MPM patients is often disappointing, regardless of the modality used. Inter-individual variability of response to multimodal treatment remains a challenge and generally the MPM prognosis continues to be poor. Knowledge of predicting factors of outcome is currently insufficient; therefore, it would be highly desirable to find specific prognostic markers for MPM. Translational research projects are to be implemented.
authors.affiliation: Center for Thoracic Surgery, Department of Surgical and Morphological Sciences, University of Insubria, Varese, Italy;
authors.forename: Andrea
authors.initials: A
authors.lastname: Imperatori
authors.forename: Massimo
authors.initials: M
authors.lastname: Castiglioni
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Mortara
authors.forename: Elisa
authors.initials: E
authors.lastname: Nardecchia
authors.forename: Nicola
authors.initials: N
authors.lastname: Rotolo
keywords: Malignant pleural mesothelioma (MPM); prognostic factors; translational research