title: [The efficacy of imidafenacin in patients with over active bladder, nocturia, or sleep disorders (Sayama-Iruma-Hannou study)].
abstract: The effect of imidafenacin for the treatment of over active bladder (OAB), in 100 patients with urgency, nocturia or sleep disorders was examined by an open-labeled, non-randomized,non-controlled study. Prior to administration and at 4 weeks after administration (0.1 or 0 2 mg/day, p. o,), symptoms and sleep disorders were assessed using the Over Active Bladder Symptom Score (OABSS) and the Athens Insomnia Scale (AIS), respectively. After administration, OABSS scores and AIS scales were improved significantly when compared to baseline values. The change of nocturia scores was correlated closely with that of AIS scales. Imidafenacin was effective in OAB patients with urgency and nocturia. In addition, imidafenacin secondarily mitigated sleep disorders significantly.
authors.affiliation: Motokaji Clinic, Japan.
authors.forename: Tsuneki
authors.initials: T
authors.lastname: Suzuki
authors.forename: Noriyasu
authors.initials: N
authors.lastname: Uwatoko
authors.forename: Akiko
authors.initials: A
authors.lastname: Watanabe
authors.forename: Kazutoyo
authors.initials: K
authors.lastname: Miyata
mesh_terms: D000368:Aged; D018680:Cholinergic Antagonists / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D008297:Male; D053158:Nocturia / Q000188:drug therapy*; D012893:Sleep Wake Disorders / Q000188:drug therapy*; D053201:Urinary Bladder, Overactive / Q000188:drug therapy*
chemical_list: D018680:Cholinergic Antagonists; D007093:Imidazoles; C120953:imidafenacin