title: Dot by dot: analyzing the glycome using lectin microarrays.
abstract: The glycome, that is, the cohort of carbohydrates within a cell or tissue, plays a key part in diverse biological interactions involved in health and disease. Glycans are structurally complex and notoriously difficult to analyze. Lectin microarrays, a sensitive and high-throughput method for glycomic profiling, provide a global view of the glycome. In recent work, this technology has been successfully applied to a wide range of studies, from identification of glycan-based stem cell markers to the detection of pathogens and early diagnosis of disease. This review focuses on advances in the field of lectin microarrays.
authors.affiliation: Biomedical Chemistry Institute, New York University, 100 Washington Square East, Room 1001, New York, NY 10003, USA.
authors.forename: João P
authors.initials: JP
authors.lastname: Ribeiro
authors.forename: Lara K
authors.initials: LK
authors.lastname: Mahal
mesh_terms: D003116:Color; D054794:Glycomics / Q000379:methods*; D006031:Glycosylation; D006801:Humans; D037102:Lectins / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry
chemical_list: D037102:Lectins; D011134:Polysaccharides