title: [Blood lipids in Chilean children 10-14 years of age].
abstract: OBJECTIVE
  Plasma lipid levels in children and adolescents are evaluated with international references. The objective was to describe them in Chilean students, to compare them with the most used reference (Lipids Research Clinics Program) and the cut-off points recommended in 2011.
  
  
  METHODS
  Cross-sectional study in 3325 children, 10 to 14 years of age. Anthropometry and auto-report of pubertal development were performed. A 12 hours fast blood sample was taken to measure total (TC), highdensity lipoprotein cholesterol (HDLC) and triglycerides (TG). Low-density lipoprotein cholesterol (LDLC) was calculated with Friedewald formula. Variables were described, Hochberg test for multiple comparisons and stepwise lineal regression were applied. The degree of agreement between local percentiles and the two international references was studied.
  
  
  RESULTS
  We studied 3,063 children, 11.4 ± 0.9 years old, 53% girls, 20.9% pre-pubertal, 22.6% had overweight, and 15.8% obesity. Averages: TC: 159.2 ± 28.3, HDLC: 51.9 ± 12.1, LDLC: 89.0 ± 31.5 and TG: 93.2 ± 60 mg/dL. Boys had higher HDLC: 53.3 ± 12.2 vs. 50.6 ± 11.8 mg/dL and lower TG: 86.2 ± 58.2 vs. 99.5 ± 61.7 mg/dL than girls (p < 0,001). Influences of nutritional status, sex and age were significant. We founded high agreement with the reference for TC and LDLC, but HDLC levels were lower and TG were higher, for their cut-off points: percentiles 10th and 95th, respectively.
  
  
  CONCLUSIONS
  Blood lipids were influenced by nutritional status, sex and age. Percentile values were comparable to the international reference except for HDLC and TG, showing a more atherogenic pattern.
authors.affiliation: Departamento de Pediatría, Facultad de Medicina, Pontificia Universidad Católica de Chile, Chile.
authors.forename: Salesa
authors.initials: S
authors.lastname: Barja
authors.forename: Ximena
authors.initials: X
authors.lastname: Barrios
authors.forename: Pilar
authors.initials: P
authors.lastname: Arnaiz
authors.forename: Angélica
authors.initials: A
authors.lastname: Domínguez
authors.forename: Luis
authors.initials: L
authors.lastname: Villarroel
authors.forename: Oscar
authors.initials: O
authors.lastname: Castillo
authors.forename: Marcelo
authors.initials: M
authors.lastname: Farías
authors.forename: Catterina
authors.initials: C
authors.lastname: Ferreccio
authors.forename: Francisco
authors.initials: F
authors.lastname: Mardones
mesh_terms: D000293:Adolescent; D002648:Child; D002677:Chile; D008076:Cholesterol, HDL / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D014280:Triglycerides / Q000097:blood*
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides