title: A case of tracheobronchial amyloidosis treated with endoscopic debulking and external beam radiation therapy.
abstract: We report on a 55-year-old patient who was admitted to hospital because of recurrent pneumonia. CT imaging provided airway narrowing and mural thickening of the distal trachea and mainstem bronchi, compatible with endobronchial polypoid, toric-shaped changes of the distal tracheal wall spreading into both the left and right bronchial system. Bronchoscopy was performed and biopsies revealed the diagnosis of tracheobronchial amyloidosis. We performed a combination of bronchoscopic debulking and consecutive external beam radiation therapy with the result of no further progression of the disease, stable endobronchial situation, and functional improvements at a follow up at 6 months.
authors.affiliation: Department of Respiratory and Critical Care Medicine, Ludwig-Boltzmann-Institute for COPD and Respiratory Epidemiology, Otto Wagner Hospital, Vienna, Austria.
authors.forename: I
authors.initials: I
authors.lastname: Firlinger
authors.forename: U
authors.initials: U
authors.lastname: Setinek
authors.forename: H
authors.initials: H
authors.lastname: Koller
authors.forename: P
authors.initials: P
authors.lastname: Feurstein
authors.forename: H
authors.initials: H
authors.lastname: Prosch
authors.forename: O C
authors.initials: OC
authors.lastname: Burghuber
authors.forename: A
authors.initials: A
authors.lastname: Valipour
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis / Q000628:therapy*; D001982:Bronchial Diseases / Q000175:diagnosis / Q000628:therapy*; D003131:Combined Modality Therapy / Q000379:methods; D004724:Endoscopy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020266:Radiotherapy, Conformal / Q000379:methods*; D014133:Tracheal Diseases / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome