title: Application of immediate breast reconstruction with silicon prosthetic implantation following bilateral mammary gland excision in treatment of young patients with early breast cancer.
abstract: OBJECTIVE
  To evaluate the application of immediate breast reconstruction (IBR) with silicon prosthetic implantation following bilateral nipple-preserving subcutaneous mammary gland excision in the treatment of young patients with early breast cancer.
  
  
  METHODS
  We retrospectively analyzed the clinical data of 21 patients with breast cancer who were performed on IBR following bilateral nipple-preserving subcutaneous mammary gland excision in our hospital from January 2006 to March 2011.
  
  
  RESULTS
  The operations were successful in all the 21 patients. Also, the treatment provided a good cosmetic effect. No local recurrence or distant metastasis was found in these 21 patients during the 6-66-month follow-up.
  
  
  CONCLUSIONS
  For the young patients with early breast cancer, mammary gland excision on the affected side along with prophylactic excision of the contralateral side, namely IBR following bilateral nipple-preserving subcutaneous mammary gland excision, provides good clinical effectiveness and cosmetological effects.
authors.affiliation: Division of Breast Surgery, Department of General Surgery, General Hospital of Chinese People's Liberation Army (301 Hospital), Beijing, China;
authors.forename: Xi-Ru
authors.initials: XR
authors.lastname: Li
authors.forename: Yan-Jun
authors.initials: YJ
authors.lastname: Zhang
authors.forename: Jian-Dong
authors.initials: JD
authors.lastname: Wang
authors.forename: Liu-Quan
authors.initials: LQ
authors.lastname: Cheng
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.forename: Yi-Qiong
authors.initials: YQ
authors.lastname: Zheng
authors.forename: Xin
authors.initials: X
authors.lastname: Tang
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.forename: Ying
authors.initials: Y
authors.lastname: Gao
keywords: Breast cancer; immediate breast reconstruction; prophylactic mastectomy