title: Functionalized liposome purification via Liposome Extruder Purification (LEP).
abstract: Liposome Extruder Purification (LEP) allows for the rapid purification of diverse liposome formulations using the same extrusion apparatus employed during liposome formation. The LEP process provides a means for purifying functionalized liposomes from non-conjugated drug or protein contaminants with >93% liposome recovery and >93% contaminant removal in a single step.
authors.affiliation: Department of Chemical and Biomolecular Engineering, University of Notre Dame, 165 Fitzpatrick Hall, Notre Dame, IN 46556-5637, USA.
authors.forename: Nathan J
authors.initials: NJ
authors.lastname: Alves
authors.forename: William
authors.initials: W
authors.lastname: Cusick
authors.forename: Jared F
authors.initials: JF
authors.lastname: Stefanick
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Ashley
authors.forename: Michael W
authors.initials: MW
authors.lastname: Handlogten
authors.forename: Basar
authors.initials: B
authors.lastname: Bilgicer
mesh_terms: D000818:Animals; D002417:Cattle; D005591:Chemical Fractionation / Q000379:methods*; D002626:Chemistry, Pharmaceutical; D008081:Liposomes / Q000737:chemistry / Q000302:isolation & purification*; D013997:Time Factors
chemical_list: D008081:Liposomes