title: Nanostructure-induced DNA condensation.
abstract: The control of the DNA condensation process is essential for compaction of DNA in chromatin, as well as for biological applications such as nonviral gene therapy. This review endeavours to reflect the progress of investigations on DNA condensation effects of nanostructure-based condensing agents (such as nanoparticles, nanotubes, cationic polymer and peptide agents) observed by using atomic force microscopy (AFM) and other techniques. The environmental effects on structural characteristics of nanostructure-induced DNA condensates are also discussed.
authors.affiliation: National Center for Nanoscience and Technology (NCNST), Beijing 100190, PR China.
authors.forename: Ting
authors.initials: T
authors.lastname: Zhou
authors.forename: Axel
authors.initials: A
authors.lastname: Llizo
authors.forename: Chen
authors.initials: C
authors.lastname: Wang
authors.forename: Guiying
authors.initials: G
authors.lastname: Xu
authors.forename: Yanlian
authors.initials: Y
authors.lastname: Yang
mesh_terms: D004247:DNA / Q000737:chemistry*; D050091:Dendrimers / Q000737:chemistry; D015316:Genetic Therapy; D006801:Humans; D049329:Nanostructures / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry; D004364:Pharmaceutical Preparations / Q000737:chemistry; D011108:Polymers / Q000737:chemistry
chemical_list: D050091:Dendrimers; D010455:Peptides; D004364:Pharmaceutical Preparations; D011108:Polymers; D004247:DNA