title: Infections in the elderly.
abstract: Infections have plagued humans since the beginning of recorded history. Huge segments of the human population were episodically wiped out by epidemic infectious diseases in past centuries. Infection was and is often the final cause of mortality in the debilitated elderly. Substantial ongoing research has been performed to investigate mechanisms, causes, pathogenesis, and therapy for infectious disease. Much of this work has involved the elderly because that group is uniquely predisposed to morbidity and mortality from infection. It is hoped that continued research will result in a decrease in infection morbidity and mortality in elderly.
authors.forename: Hans Jürgen
authors.initials: HJ
authors.lastname: Hepper
authors.forename: Cornel
authors.initials: C
authors.lastname: Sieber
authors.forename: Sieber
authors.initials: S
authors.lastname: Cornel
authors.forename: Peter
authors.initials: P
authors.lastname: Walger
authors.forename: Walger
authors.initials: W
authors.lastname: Peter
authors.forename: Philipp
authors.initials: P
authors.lastname: Bahrmann
authors.forename: Bahrmann
authors.initials: B
authors.lastname: Philipp
authors.forename: Katrin
authors.initials: K
authors.lastname: Singler
authors.forename: Singler
authors.initials: S
authors.lastname: Katrin
mesh_terms: D000203:Activities of Daily Living; D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000276:immunology* / Q000502:physiology; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D019090:Case Management / Q000592:standards; D002908:Chronic Disease; D003141:Communicable Diseases / Q000150:complications / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D015897:Comorbidity; D003693:Delirium / Q000209:etiology; D018450:Disease Progression; D016330:Frail Elderly; D006801:Humans; D011379:Prognosis; D018570:Risk Assessment; D055948:Sarcopenia
chemical_list: D000890:Anti-Infective Agents
keywords: Elderly; Functional decline; Geriatric; Immune senescence; Infections; Pneumonia; Sepsis