title: [Cowden syndrome].
abstract: BACKGROUND
  Cowden syndrome is rare; oral symptoms are not always diagnosed. This case of Cowden syndrome was revealed by gingival hypertrophy.
  
  
  METHODS
  A 21-year-old female patient consulted for gingival hypertrophy and multiple papules in the mouth. She had a history of thyroid lobectomy due to a goiter. The gingival papillomatosis and the goiter suggested a Cowden syndrome. The diagnosis was confirmed clinically by facial skin papules.
  
  
  CONCLUSIONS
  Cutaneous and oral lesions are usually the first symptoms of the syndrome. Diffuse gingival papillomatosis may suggest a Cowden syndrome and should lead to screen for associated symptoms. A high-risk diagnosis of breast and thyroid cancer is associated to Cowden syndrome and the patient should have a yearly follow-up.
authors.affiliation: Service de parodontologie, faculté de médecine dentaire, université Mohammed V Souissi, Rabat, Morocco. o.ennibi@um5s.net.ma
authors.forename: O
authors.initials: O
authors.lastname: Ennibi
authors.forename: M
authors.initials: M
authors.lastname: Guedira
authors.forename: N
authors.initials: N
authors.lastname: Amrani
mesh_terms: D002432:Cecum; D005260:Female; D005886:Gingival Hypertrophy / Q000175:diagnosis* / Q000209:etiology; D006223:Hamartoma Syndrome, Multiple / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007417:Intestinal Polyps / Q000175:diagnosis / Q000209:etiology; D055815:Young Adult