title: [Multicentre study on hepatic adenomas].
abstract: BACKGROUND
  Hepatic adenomas (HA) are benign tumours which can present serious complications, and as such, in the past all were resected. It has now been shown that those smaller than 3 cm not expressing β-catenin only result in complications in exceptional cases and therefore the therapeutic strategy has been changed.
  
  
  METHODS
  Retrospective study in 14 HPB units.
  
  
  METHODS
  patients with resected and histologically confirmed HA.
  
  
  METHODS
  1995-2011.
  
  
  RESULTS
  81 patients underwent surgery. Age: 39.5 years (range: 14-75). Sex: female (75%). Consumption of oestrogen in women: 33%. Size: 8.8 cm (range, 1-20 cm). Only 6 HA (7.4%) were smaller than 3 cm. The HA median was 1 (range: 1-12). Nine patients had adenomatosis (>10HA). A total of 51% of patients displayed symptoms, the most frequent (77%) being abdominal pain. Eight patients (10%) began with acute abdomen due to rupture and/or haemorrhage. A total of 67% of the preoperative diagnoses were correct. Surgery was scheduled for 90% of patients. The techniques employed were: major hepatectomy (22%), minor hepatectomy (77%) and one liver transplantation. A total of 20% were performed laparoscopically. The morbidity rate was 28%. There were no cases of mortality. Three patients had malignisation (3.7%). The follow-up period was 43 months (range 1-192). Two recurrences were detected and resected.
  
  
  CONCLUSIONS
  Patients with resected HA are normally women with large lesions and oestrogen consumption was lower than expected. Its correct preoperative diagnosis is acceptable (70%). The major hepatectomy rate is 25% and the laparoscopy rate is 20%. There was a low morbidity rate and no mortality.
authors.affiliation: Unidad Hepatobiliopancreática, Servicio de Cirugía, Hospital Universitario de Guadalajara, Guadalajara, España. Electronic address: jose_ramia@hotmail.com.
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Ramia
authors.affiliation: Sección Hepatobiliopancreática y de Trasplante Hepático, Servicio de Cirugía, Hospital Central de Asturias, Oviedo, España.
authors.forename: Carmen
authors.initials: C
authors.lastname: Bernardo
authors.affiliation: Unidad Hepatobiliopancreática y de Trasplante Hepático, Servicio de Cirugía, Hospital de Cruces, Bilbao, España.
authors.forename: Andrés
authors.initials: A
authors.lastname: Valdivieso
authors.affiliation: Unidad Hepatobiliopancreática y de Trasplante Hepático, Servicio de Cirugía, Hospital Vall d'Hebron, Barcelona, España.
authors.forename: Cristina
authors.initials: C
authors.lastname: Dopazo
authors.affiliation: Unidad Hepatobiliopancreática, Servicio de Cirugía, Hospital de la Cruz Roja, Getafe, Madrid, España.
authors.forename: José María
authors.initials: JM
authors.lastname: Jover
authors.affiliation: Unidad Hepatobiliopancreática, Servicio de Cirugía, Hospital Josep Trueta, Girona, España.
authors.forename: M Teresa
authors.initials: MT
authors.lastname: Albiol
authors.affiliation: Unidad Hepatobiliopancreática, Servicio de Cirugía, Clínica Universitaria de Navarra, Pamplona, España.
authors.forename: Fernando
authors.initials: F
authors.lastname: Pardo
authors.affiliation: Unidad Hepatobiliopancreática, Unidad de Gestión Clinica de Cirugía General, Digestiva y Trasplantes, Servicio de Cirugía, Hospital Carlos Haya, Málaga, España.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Fernandez Aguilar
authors.affiliation: Unidad Hepatobiliopancreática, Servicio de Cirugía, Hospital Príncipe de Asturias, Alcalá de Henares, Madrid, España.
authors.forename: Alberto
authors.initials: A
authors.lastname: Gutierrez Calvo
authors.affiliation: Unidad Hepatobiliopancreática, Servicio de Cirugía, Hospital Miguel Servet, Zaragoza, España.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Serrablo
authors.affiliation: Unidad Hepatobiliopancreática, Servicio de Cirugía, Hospital Clínico San Carlos, Madrid, España.
authors.forename: Luis
authors.initials: L
authors.lastname: Diez Valladares
authors.affiliation: Servicio de Cirugía, Hospital de Fuenlabrada, Fuenlabrada, Madrid, España.
authors.forename: Fernando
authors.initials: F
authors.lastname: Pereira
authors.affiliation: Unidad Hepatobiliopancreática, Servicio de Cirugía, Hospital Clínico Universitario, Valencia, España.
authors.forename: Luis
authors.initials: L
authors.lastname: Sabater
authors.affiliation: Unidad Hepatobiliopancreática, Servicio de Cirugía, Hospital Virgen de las Nieves, Granada, España.
authors.forename: Karim
authors.initials: K
authors.lastname: Muffak
authors.affiliation: Unidad Hepatobiliopancreática, Servicio de Cirugía, Hospital Josep Trueta, Girona, España.
authors.forename: Joan
authors.initials: J
authors.lastname: Figueras
mesh_terms: D000236:Adenoma / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
keywords: Adenoma; Cirugía; Hígado; Liver; Review; Surgery