title: Space filling of β-cyclodextrin and β-cyclodextrin derivatives by volatile hydrophobic guests.
abstract: The inclusion of volatile derivatives of benzene and cyclohexane in β-cyclodextrin (β-CD), hydroxypropyl-β-CD, and hydrophilic β-CD-thioethers was investigated by static headspace gas chromatography (HS-GC) and molecular modelling. The obtained binding constants strongly increase with the amount of space filling of the CD cavity and the salt concentration. β-CD thioethers show a 3-10 times higher binding potential than native β-CD.
authors.affiliation: University Lille Nord de France, F-59000 Lille, France ; ULCO, UCEIV, F-59140 Dunkerque, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Fourmentin
authors.forename: Anca
authors.initials: A
authors.lastname: Ciobanu
authors.forename: David
authors.initials: D
authors.lastname: Landy
authors.forename: Gerhard
authors.initials: G
authors.lastname: Wenz
keywords: cyclodextrins; inclusion compound; molecular modelling; space filling; static headspace gas chromatography; vapor pressure