title: Asymmetric copper(I)-catalyzed azide-alkyne cycloaddition to quaternary oxindoles.
abstract: We report a highly enantioselective Cu(I)-catalyzed azide-alkyne cycloaddition via asymmetric desymmetrization of oxindole-based 1,6-heptadiynes, which furnishes quaternary oxindoles bearing a 1,2,3-triazole-containing moiety with 84-98% ee.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Zhou
authors.forename: Chen
authors.initials: C
authors.lastname: Tan
authors.forename: Jing
authors.initials: J
authors.lastname: Tang
authors.forename: Yan-Yan
authors.initials: YY
authors.lastname: Zhang
authors.forename: Wei-Ming
authors.initials: WM
authors.lastname: Gao
authors.forename: Hai-Hong
authors.initials: HH
authors.lastname: Wu
authors.forename: Yi-Hua
authors.initials: YH
authors.lastname: Yu
authors.forename: Jian
authors.initials: J
authors.lastname: Zhou