title: Malignant peripheral nerve sheath tumor of the chest wall associated with neurofibromatosis: a case report.
abstract: Primary chest wall tumors are relatively rare and represent approximately 5% of all thoracic neoplasms. Malignant peripheral nerve sheath tumor (MPNST) is highly aggressive and occurs in the second or third decade of patients with neurofibromatosis type 1 (NF-1). The estimated incidence of MPNST in patients with NF-1 is 2-5% (general population, 0.001%). This neoplasm usually affects the extremities and rarely the thoracic cavity. We present a case of MPNST of the chest wall in a patient with NF-1 who developed local recurrence 5 months after complete surgical resection and postoperative adjuvant radiotherapy.
authors.affiliation: Division of Thoracic Surgery and Department of Surgery, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan; ; Division of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, Taipei 114, Taiwan;
authors.forename: Chin-Chieh
authors.initials: CC
authors.lastname: Hsu
authors.forename: Tsai-Wang
authors.initials: TW
authors.lastname: Huang
authors.forename: Jane-Yi
authors.initials: JY
authors.lastname: Hsu
authors.forename: Nieh
authors.initials: N
authors.lastname: Shin
authors.forename: Hung
authors.initials: H
authors.lastname: Chang
keywords: Malignant peripheral nerve sheath tumor (MPNST); chest wall tumor; neurofibromatosis type 1