title: Non-healing ulcer on the foot: early onset unilateral Mali-type acroangiodermatitis.
abstract: Acroangiodermatitis (pseudo-Kaposi's sarcoma, AAD) is a benign vascular dermatosis that resembles Kaposi's sarcoma clinically and histopathologically (1). Four types have been defined: the Stewart-Bluefarb type accompanying chronic arteriovenous malformations, the Mali type accompanying stasis dermatitis, a type accompanying the first gestation, and a type accompanying arteriovenous shunts in patients with chronic kidney failure (3). Although AAD development is associated with chronic venous failure, less frequently AAD can develop as a complication of extremity paralysis, hemodialysis, post-traumatic arteriovenous fistula, amputated extremities, and vascular malformations (e.g., Klippel-Trénaunay syndrome). Pseudo-Kaposi's sarcoma can be histopathologically and clinically confused with malignant diseases such as Kaposi's sarcoma (1, 4). A 22-year-old male was referred to our outpatient clinic with a complaint of a non-healing wound on the distal phalanx of the left first toe. The patient was referred to various centers for 2 years and stated that he had received infection treatments but that his complaints did not disappear. An AAD diagnosis was established for the patient based on clinical and histopathologic evidence. Because he had early-onset disease and it was unilateral, the diagnosis was delayed. In addition, due to the rare occurrence of the disease, we histopathologically diagnosed this patient as having acroangiodermatitis.
authors.affiliation: Bezmiâlem Vakif University, Medical Faculty, Department of Dermatology, Istanbul, Turkey. dilekozkaya@gmail.com
authors.forename: Dilek Bıyık
authors.initials: DB
authors.lastname: Ozkaya
authors.forename: Ozlem
authors.initials: O
authors.lastname: Su
authors.forename: Nahide
authors.initials: N
authors.lastname: Onsun
authors.forename: Hande
authors.initials: H
authors.lastname: Ulusal
authors.forename: Cuyan
authors.initials: C
authors.lastname: Demirkesen
mesh_terms: D000169:Acrodermatitis / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D016523:Foot Ulcer / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D035583:Rare Diseases; D018570:Risk Assessment; D012514:Sarcoma, Kaposi / Q000175:diagnosis / Q000473:pathology*; D012720:Severity of Illness Index; D017445:Skin Diseases, Vascular / Q000175:diagnosis / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology; D014034:Toes / Q000473:pathology*; D055815:Young Adult