title: Ultrasound methodology used to construct the fetal growth standards in the INTERGROWTH-21st Project.
abstract: A unified protocol is essential to ensure that fetal ultrasound measurements taken in multicentre research studies are accurate and reproducible. This paper describes the methodology used to take two-dimensional, ultrasound measurements in the longitudinal, fetal growth component of the INTERGROWTH-21(st) Project. These standardised methods should minimise the systematic errors associated with pooling data from different study sites. They represent a model for carrying out similar research studies in the future.
authors.affiliation: Nuffield Department of Obstetrics & Gynaecology and Oxford Maternal & Perinatal Health Institute, Green Templeton College, University of Oxford, Oxford, UK.
authors.forename: A T
authors.initials: AT
authors.lastname: Papageorghiou
authors.forename: I
authors.initials: I
authors.lastname: Sarris
authors.forename: C
authors.initials: C
authors.lastname: Ioannou
authors.forename: T
authors.initials: T
authors.lastname: Todros
authors.forename: M
authors.initials: M
authors.lastname: Carvalho
authors.forename: G
authors.initials: G
authors.lastname: Pilu
authors.forename: L J
authors.initials: LJ
authors.lastname: Salomon
mesh_terms: D000653:Amniotic Fluid / Q000000981:diagnostic imaging; D001837:Body Weights and Measures / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D002985:Clinical Protocols; D005260:Female; D047109:Fetal Development; D005865:Gestational Age; D057238:Growth Charts; D006801:Humans; D008137:Longitudinal Studies / Q000379:methods / Q000592:standards; D015337:Multicenter Studies as Topic / Q000379:methods* / Q000592:standards; D010920:Placenta / Q000000981:diagnostic imaging; D011247:Pregnancy; D012107:Research Design / Q000592:standards; D016216:Ultrasonography, Prenatal / Q000295:instrumentation / Q000379:methods* / Q000592:standards
keywords: Fetal biometry; INTERGROWTH-21st; fetal growth; standards; ultrasound