title: Unusual orange-colored choroidal metastases.
abstract: OBJECTIVE
  To report the clinical and paraclinical features of two patients with orange- colored choroidal metastases in whom the primary cancers have not previously been associated with such lesions.
  
  
  METHODS
  Orange-colored choroidal lesions were detected on the fundus examination of one patient with metastatic small cell neuroendocrine tumor of the larynx and oropharynx, and in another subject with metastatic alveolar soft part sarcoma of the leg. Although ultrasonographic characteristics of the choroidal masses were comparable to those of choroidal hemangiomas, fluorescein angiography revealed delayed initial fluorescence along with minimal fluorescence in subsequent phases of the angiogram which were in clear distinction from the earlier appearing and progressively intense fluorescence observed with circumscribed choroidal hemangiomas.
  
  
  CONCLUSIONS
  Small cell neuroendocrine tumors and alveolar soft part sarcomas should be considered among the differential diagnoses for orange-colored choroidal metastases. Identifying these choroidal lesions could facilitate localizing the occult primary tumor. Fluorescein angiography may differentiate a unifocal orange choroidal metastasis from a circumscribed choroidal hemangioma.
authors.affiliation: Departments of Ocular & Radiation Oncology, Princess Margaret Cancer Center, University of Toronto, Toronto, ON, Canada.
authors.forename: Hatem
authors.initials: H
authors.lastname: Krema
authors.forename: Hugh
authors.initials: H
authors.lastname: McGowan
authors.forename: Herbert
authors.initials: H
authors.lastname: Tanzer
authors.forename: Rand
authors.initials: R
authors.lastname: Simpson
authors.forename: Normand
authors.initials: N
authors.lastname: Laperriere
keywords: Color; Eye; Metastasis; Neuroendocrine; Orange; Sarcoma