title: How did the chicken cross the road? With her striatal cholinergic interneurons, of course.
abstract: Recognizing when the world changes is fundamental for normal learning. In this issue of Neuron, Bradfield et al. (2013) show that cholinergic interneurons in dorsomedial striatum are critical to the process whereby new states of the world are appropriately registered and retrieved during associative learning.
authors.affiliation: Behavioral Neuroscience Branch, NIDA/IRP/NIH/DHHS, Baltimore, MD 21224, USA. geoffrey.schoenbaum@nih.gov
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Schoenbaum
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Stalnaker
authors.forename: Yael
authors.initials: Y
authors.lastname: Niv
mesh_terms: D000818:Animals; D059329:Cholinergic Neurons / Q000502:physiology*; D003342:Corpus Striatum / Q000502:physiology*; D007395:Interneurons / Q000502:physiology*; D007858:Learning / Q000502:physiology*; D008297:Male; D013788:Thalamus / Q000502:physiology*