title: Immediate Placement and Provisionalization of Implants Into Sites With Periradicular Infection With and Without Antibiotics: An Exploratory Study.
abstract: This study explored the necessity of perioperative antibiotics on survival rates of implants immediately placed and provisionalized into sites with infection. Subjects were randomly assigned into antibiotic or placebo groups. Extraction, immediate placement, and provisionalization of an implant were performed. Eight subjects received placebo and five subjects received both a pre- and post-operative antibiotic regimen. One implant from each group failed. Perioperative antibiotic therapy may not be needed in selected immediate implant therapy.
authors.affiliation: 1  Department of Prosthodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC.
authors.forename: Edward
authors.initials: E
authors.lastname: Givens
authors.affiliation: 1  Department of Prosthodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC.|2  Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, NC.
authors.forename: Sompop
authors.initials: S
authors.lastname: Bencharit
authors.affiliation: 3  School of Dentistry, University of North Carolina, Chapel Hill, NC.
authors.forename: Warren C
authors.initials: WC
authors.lastname: Byrd
authors.affiliation: 4  Department of Orthodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC.
authors.forename: Ceib
authors.initials: C
authors.lastname: Phillips
authors.affiliation: 5  Department of Endodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC.
authors.forename: Bashir
authors.initials: B
authors.lastname: Hosseini
authors.affiliation: 6  Department of Diagnostic Sciences, School of Dentistry, University of North Carolina, Chapel Hill, NC.
authors.forename: Donald
authors.initials: D
authors.lastname: Tyndall
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019250:Dental Implants, Single-Tooth; D019094:Dental Prosthesis, Implant-Supported; D006801:Humans; D057893:Immediate Dental Implant Loading; D017053:Infection Control; D007239:Infections; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents
keywords: antibiotics; apical infection; dental implants; immediate placement; immediate provisional restoration; randomized controlled trial