title: Recent expansions in an emergent novel drug delivery technology: Emulgel.
abstract: Emulgel is an emerging topical drug delivery system to which if more effort is paid towards its formulation & development with more number of topically effective drugs it will prove a boon for derma care & cosmetology. Emulgels are either emulsion of oil in water or water in oil type, which is gelled by mixing it with gelling agent. Incorporation of emulsion into gel increases its stability & makes it a dual control release system. Due to lack of excess oily bases & insoluble excipients, it shows better drug release as compared to other topical drug delivery system. Presence of gel phase makes it a non greasy & favors good patient compliance. These reviews give knowledge about Emulgel including its properties, advantages, formulation considerations, and its recent advances in research field. All factors such as selection of gelling agent, oil agent, emulsifiers influencing the stability and efficacy of Emulgel are discussed. All justifications are described in accordance with the research work carried out by various scientists. These brief reviews on formulation method have been included. Current research works that carried out on Emulgel are also discussed and highlighted the wide utility of Emulgel in topical drug delivery system. After the vast study, it can be concluded that the Emulgels appear better & effective drug delivery system as compared to other topical drug delivery system. The comprehensive analysis of rheological and release properties will provide an insight into the potential usage of Emulgel formulation as drug delivery system.
authors.affiliation: Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, India. Electronic address: write2ajaz@gmail.com.
authors.lastname: Ajazuddin
authors.forename: Amit
authors.initials: A
authors.lastname: Alexander
authors.forename: Ajita
authors.initials: A
authors.lastname: Khichariya
authors.forename: Saurabh
authors.initials: S
authors.lastname: Gupta
authors.forename: Ravish J
authors.initials: RJ
authors.lastname: Patel
authors.forename: Tapan Kumar
authors.initials: TK
authors.lastname: Giri
authors.forename: Dulal Krishna
authors.initials: DK
authors.lastname: Tripathi
mesh_terms: D000818:Animals; D002626:Chemistry, Pharmaceutical; D004333:Drug Administration Routes; D016503:Drug Delivery Systems; D004655:Emulsions; D005782:Gels; D006801:Humans; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*
chemical_list: D004655:Emulsions; D005782:Gels; D004364:Pharmaceutical Preparations
keywords: Cosmetic; Emulgel; Emulsion; Gelling agent; Thixotropic; Topical