title: Zn(2+)-induced conformational changes in a binaphthyl-pyrene derivative monitored by using fluorescence and CD spectroscopy.
abstract: We have developed a unique binaphthyl-pyrene system 1, whose dihedral angle is reversibly modulated by the addition of Zn(2+). Dihedral angle changes in this system were monitored by using circular dichroism (CD) and by an observed "off-on" fluorescence enhancement in aqueous solution. Owing to these changes, the presence of biologically important Zn(2+) ions in samples can be readily monitored by employing CD and fluorescence spectroscopy. Finally, the experimental observations made in this effort are supported by the results of quantum mechanical calculations.
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.forename: Jong Hun
authors.initials: JH
authors.lastname: Moon
authors.forename: Raju
authors.initials: R
authors.lastname: Nandhakumar
authors.forename: Baotao
authors.initials: B
authors.lastname: Kang
authors.forename: Dabin
authors.initials: D
authors.lastname: Kim
authors.forename: Kwan Mook
authors.initials: KM
authors.lastname: Kim
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Lee
authors.forename: Juyoung
authors.initials: J
authors.lastname: Yoon