title: A spliceosome protein is essential for glioma stem cell viability.
abstract: PHF5A-mediated exon recognition is selectively required for GSC viability and tumor formation.
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000235:genetics; D004268:DNA-Binding Proteins; D059565:G2 Phase Cell Cycle Checkpoints; D005910:Glioma / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D051379:Mice; D014411:Neoplastic Stem Cells / Q000378:metabolism / Q000473:pathology; D016601:RNA-Binding Proteins; D017411:Ribonucleoproteins, Small Nuclear / Q000378:metabolism*; D017381:Spliceosomes / Q000378:metabolism; D015534:Trans-Activators
chemical_list: D002352:Carrier Proteins; D004268:DNA-Binding Proteins; C459458:Phf5a protein, mouse; D016601:RNA-Binding Proteins; D017411:Ribonucleoproteins, Small Nuclear; D015534:Trans-Activators