title: What we are watching--five top global infectious disease threats, 2012: a perspective from CDC's Global Disease Detection Operations Center.
abstract: Disease outbreaks of international public health importance continue to occur regularly; detecting and tracking significant new public health threats in countries that cannot or might not report such events to the global health community is a challenge. The Centers for Disease Control and Prevention's (CDC) Global Disease Detection (GDD) Operations Center, established in early 2007, monitors infectious and non-infectious public health events to identify new or unexplained global public health threats and better position CDC to respond, if public health assistance is requested or required. At any one time, the GDD Operations Center actively monitors approximately 30-40 such public health threats; here we provide our perspective on five of the top global infectious disease threats that we were watching in 2012: 1 avian influenza A (H5N1), 2 cholera, 3 wild poliovirus, 4 enterovirus-71, and 5 extensively drug-resistant tuberculosis11†Current address: Division of Integrated Biosurveillance, Armed Forces Health Surveillance Center, US Department of Defense, Silver Spring, MD, USA.
authors.affiliation: Division of Global Disease Detection and Emergency Response, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA. DOT9@cdc.gov
authors.forename: Kira A
authors.initials: KA
authors.lastname: Christian
authors.forename: Kashef
authors.initials: K
authors.lastname: Ijaz
authors.forename: Scott F
authors.initials: SF
authors.lastname: Dowell
authors.forename: Catherine C
authors.initials: CC
authors.lastname: Chow
authors.forename: Rohit A
authors.initials: RA
authors.lastname: Chitale
authors.forename: Joseph S
authors.initials: JS
authors.lastname: Bresee
authors.forename: Eric
authors.initials: E
authors.lastname: Mintz
authors.forename: Mark A
authors.initials: MA
authors.lastname: Pallansch
authors.forename: Steven
authors.initials: S
authors.lastname: Wassilak
authors.forename: Eugene
authors.initials: E
authors.lastname: McCray
authors.forename: Ray R
authors.initials: RR
authors.lastname: Arthur
mesh_terms: D000818:Animals; D055877:Biosurveillance; D001717:Birds; D002487:Centers for Disease Control and Prevention, U.S.; D002771:Cholera / Q000453:epidemiology / Q000517:prevention & control; D003140:Communicable Disease Control; D004196:Disease Outbreaks / Q000517:prevention & control*; D024901:Drug Resistance, Multiple, Bacterial; D029821:Enterovirus A, Human; D004769:Enterovirus Infections / Q000453:epidemiology / Q000517:prevention & control; D014943:Global Health; D006801:Humans; D053124:Influenza A Virus, H5N1 Subtype; D005585:Influenza in Birds / Q000453:epidemiology / Q000517:prevention & control; D011051:Poliomyelitis / Q000453:epidemiology / Q000517:prevention & control; D017955:Poliovirus; D014376:Tuberculosis / Q000453:epidemiology / Q000517:prevention & control; D014481:United States
keywords: CDC; disease detection; emergency response; epidemic intelligence; epidemiology; global health