title: Comparative evaluation of antimicrobial efficacy of various root canal filling materials along with aloevera used in primary teeth: a microbiological study.
abstract: OBJECTIVE
  this study was conducted to evaluate the antimicrobial effectiveness of 6 root canal filling materials and a negative control agent against 18 strains of bacteria isolated from infected root canals of primary molar teeth using agar diffusion assay.
  
  
  METHODS
  Aloevera with sterile water Zinc oxide and Eugenol, Zinc oxide-Eugenol with aloevera, Calcium hydroxide and sterile water, Calcium hydroxide with sterile water and aloevera, Calcium hydroxide and Iodoform (Metapex) and Vaseline (Control). MIC and MBC of aloevera was calculated.
  
  
  RESULTS
  All materials except Vaseline showed varied antimicrobial activity against the test bacterias. The zones of inhibition were ranked into 4 inhibition categories based on the proportional distribution of the data. All the 18 bacterial isolates were classified under 2 groups based on Gram positive and Gram negative aerobes. Statistical analysis was carried out to compare the antimicrobial effectiveness between materials tested with each of the bacterial groupings.
  
  
  CONCLUSIONS
  Aloevera + Sterile Water was found to have superior antimicrobial activity against most of the microorganisms followed by ZOE + Aloevera, calcium hydroxide + Aloevera, ZOE, calcium hydroxide, Metapex in the descending order and Vaseline showed no inhibition.
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Sharad Pawar Dental College and Hospital, Wardha, Maharashtra, India. Ritika.kriplani@gmail.com
authors.forename: R
authors.initials: R
authors.lastname: Kriplani
authors.forename: N
authors.initials: N
authors.lastname: Thosar
authors.forename: M S
authors.initials: MS
authors.lastname: Baliga
authors.forename: P
authors.initials: P
authors.lastname: Kulkarni
authors.forename: N
authors.initials: N
authors.lastname: Shah
authors.forename: R
authors.initials: R
authors.lastname: Yeluri
mesh_terms: D000504:Aloe; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology*; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000494:pharmacology; D002126:Calcium Hydroxide / Q000008:administration & dosage / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D003751:Dental Fistula / Q000382:microbiology; D003786:Dental Pulp Cavity / Q000382:microbiology*; D003790:Dental Pulp Necrosis / Q000382:microbiology; D004338:Drug Combinations; D006089:Gram-Negative Anaerobic Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D006847:Hydrocarbons, Iodinated / Q000008:administration & dosage / Q000494:pharmacology; D008422:Materials Testing; D008826:Microbial Sensitivity Tests; D008963:Molar / Q000382:microbiology; D010482:Periapical Abscess / Q000382:microbiology; D010577:Petrolatum / Q000494:pharmacology; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology*; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D012827:Silicone Oils / Q000008:administration & dosage / Q000494:pharmacology; D014094:Tooth, Deciduous / Q000382:microbiology*; D015035:Zinc Oxide-Eugenol Cement / Q000008:administration & dosage / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D006847:Hydrocarbons, Iodinated; C498115:Metapex; D010936:Plant Extracts; D012387:Root Canal Filling Materials; D012827:Silicone Oils; D015035:Zinc Oxide-Eugenol Cement; D010577:Petrolatum; C010473:iodoform; D002126:Calcium Hydroxide