title: Clonal diversity among Burkholderia cepacia complex isolates from cystic fibrosis patients in a reference unit.
abstract: BACKGROUND
  The epidemiology of Burkholderia cepacia complex (Bcc) in cystic fibrosis (CF) is not widely known.
  
  
  METHODS
  All CF patients with Bcc between 2002 and 2011 were reviewed, and a molecular analysis of isolates was performed.
  
  
  RESULTS
  The prevalence of Bcc infection was 7.2% (18/250). Molecular analysis of 16 Bcc isolates showed 5 species (7 B. contaminans, 6 B. cepacia, 1 B. cenocepacia, 1 B. multivorans, and 1 B. stabilis) and 13 sequence types. There were no cases of cross-transmission.
  
  
  CONCLUSIONS
  A high diversity of Bcc species was found in infected CF patients.
authors.affiliation: Servicio de Microbiología Clínica, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: Laura
authors.initials: L
authors.lastname: Barrado
authors.forename: M Teresa
authors.initials: MT
authors.lastname: Martinez
authors.forename: Jennifer
authors.initials: J
authors.lastname: Villa
authors.forename: M Ángeles
authors.initials: MÁ
authors.lastname: Orellana
authors.forename: Esther
authors.initials: E
authors.lastname: Viedma
authors.forename: Fernando
authors.initials: F
authors.lastname: Chaves
mesh_terms: D042602:Burkholderia cepacia complex / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D003550:Cystic Fibrosis / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D055815:Young Adult
keywords: Burkholderia cepacia complex; Cystic fibrosis; Epidemiología molecular; Fibrosis quística; Molecular epidemiology