title: Investigation on the effect of collagen and vitamins on biomimetic hydroxyapatite coating formation on titanium surfaces.
abstract: This study uses an in vitro experimental approach to investigate the roles of collagen and vitamins in regulating the deposition of hydroxyapatite layer on the pure titanium surface. Titanium implants were coated with a hydroxyapatite layer under biomimetic conditions by using a supersaturated calcification solution (SCS), modified by adding vitamins A and D3, and collagen. The hydroxyapatite deposits on titanium were investigated by means of scanning electron microscopy (SEM) coupled with X-ray analysis (EDX), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD) and Fourier transformed infrared (FTIR) spectroscopy. The results obtained have shown that hydroxyapatite coatings were produced in vitro under vitamins and collagen influence.
authors.affiliation: Gheorghe Asachi Technical University of Iasi, Faculty of Chemical Engineering and Environmental Protection, Prof. dr. docent Dimitrie Mangeron Rd., no. 63, zip: 700050, Iasi, Romania. gciobanu03@yahoo.co.uk
authors.forename: Gabriela
authors.initials: G
authors.lastname: Ciobanu
authors.forename: Octavian
authors.initials: O
authors.lastname: Ciobanu
mesh_terms: D000468:Alkalies / Q000494:pharmacology; D000818:Animals; D040761:Biomimetic Materials / Q000494:pharmacology*; D002417:Cattle; D020099:Coated Materials, Biocompatible / Q000494:pharmacology*; D003094:Collagen / Q000494:pharmacology*; D017886:Durapatite / Q000494:pharmacology*; D008855:Microscopy, Electron, Scanning; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D014025:Titanium / Q000494:pharmacology*; D014815:Vitamins / Q000494:pharmacology*; D014961:X-Ray Diffraction
chemical_list: D000468:Alkalies; D020099:Coated Materials, Biocompatible; D014815:Vitamins; D003094:Collagen; D017886:Durapatite; D014025:Titanium
keywords: Biomimetic coating; Collagen; Hydroxyapatite; Titanium; Vitamin