title: Management of actinic keratosis.
abstract: Actinic keratoses are common, often multiple, epidermal lesions found mainly on the sun-exposed skin of fair-skinned middle-aged and older people.(1) Over time, lesions may remain unchanged or may proliferate, regress, reappear or develop into squamous cell carcinoma (SCC).(2) Detectable (spot) lesions are often associated with alteration of the surrounding skin (field) where subclinical lesions might be present.(2) Interventions may target individual or multiple lesions or a whole field.(2) Here, we update our previous review(3) on the prevention and treatment of actinic keratoses, focusing on the licensed treatments most commonly used in the UK and recommended in UK guidelines.
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects / Q000627:therapeutic use*; D017679:Cryotherapy / Q000379:methods*; D003475:Curettage / Q000379:methods*; D006801:Humans; D055623:Keratosis, Actinic / Q000628:therapy*; D010778:Photochemotherapy / Q000379:methods*; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic; D013472:Sunlight / Q000009:adverse effects; D016896:Treatment Outcome; D006113:United Kingdom
chemical_list: D000964:Antimetabolites, Antineoplastic