title: Quality of life of adult clients on renal replacement therapies in Nepal.
abstract: OBJECTIVE
  To compare the influence of demographic and clinical variables on quality of life (QOL) amongst haemodialysis (HD) and renal transplantation clients in Nepal.
  
  
  BACKGROUND
  Renal replacement therapy in the form of renal transplant is a newer modality in Nepal. In this study, effectiveness of renal transplant and maintenance HD in clients with end-stage renal disease were evaluated in a Nepalese context.
  
  
  METHODS
  A descriptive, cross-sectional study was conducted to compare the QOL of clients undergoing HD and renal transplantation in two treatment centres in Nepal. Information on QOL was collected by using the WHOQOL-BREF instrument through interviews.
  
  
  RESULTS
  The clients in the transplantation groups were significantly younger, highly educated and employed. The QOL score of clients with renal transplantation was significantly higher in the physical, psychological and social relationship domains. While assessing QOL score in transplantation groups, females scored significantly higher score in the environmental domain compared with males.
  
  
  CONCLUSIONS
  The QOL score in renal transplant recipients was significantly better than that of clients on HD in three of the four WHOQOL-BREF domains. The limited resources and facilities for renal transplantation and the post-transplant follow-up service in Nepal might have contributed to a poorer outcome on the environmental domain in this group.
authors.affiliation: College of Nursing, Chitwan Medical College, Tribhuvan University, Bharatpur, Nepal.
authors.forename: Abja
authors.initials: A
authors.lastname: Sapkota
authors.forename: Arun
authors.initials: A
authors.lastname: Sedhain
authors.forename: Mana Kumari
authors.initials: MK
authors.lastname: Rai
mesh_terms: D000328:Adult; D015897:Comorbidity; D003906:Developing Countries; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000451:nursing* / Q000523:psychology*; D016030:Kidney Transplantation / Q000451:nursing* / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D009390:Nepal; D011788:Quality of Life / Q000523:psychology*; D006435:Renal Dialysis / Q000451:nursing* / Q000523:psychology*
keywords: Haemodialysis; Quality of life; Renal replacement therapies; Renal transplantation