title: [Analysis of risk factors of cardiogenic shock secondary to acute myocardial infarction].
abstract: OBJECTIVE
  To explore risk factors for cardiogenic shock (CS) secondary to acute myocardial infarction (AMI) patients arising from comorbidities so as to identify high risk patients earlier.
  
  
  METHODS
  A retrospective study was conducted on 5523 patients who were hospitalized with AMI in PLA General Hospital from January 1993 to December 2009. The patients were divided into two groups based on presence or absence of CS. Logistic regression analysis was used from comorbidities to evaluate the independent risk factors for CS.
  
  
  RESULTS
  Among 5523 hospitalized AMI patients, 197 (3.57%) developed CS. The 30-day in hospital mortality rate of CS group was significantly higher than that of non-CS group [55.33% (109/197) vs. 7.49% (399/5326), P<0.001]. On the basis of logistic regression analysis, advanced age [odds ratio (OR)=1.03, 95% confidence interval (95%CI) 1.02 - 1.05, P<0.001], previous attack of myocardial infarction (OR=1.57, 95%CI 1.13 - 2.19, P=0.007), history of stroke (OR=1.98, 95%CI 1.20 - 3.27, P=0.008), chronic renal failure (OR=1.76, 95%CI 1.23 - 2.51, P=0.002) and pneumonia (OR=1.72, 95%CI 1.17 - 2.52, P=0.006) were independent risk factors for CS. Using receiver operator characteristic curve (ROC curve) analysis, the model was shown a good quality to judge the outcome of CS patients as the area under curve equals 0.81 (95%CI 0.75 - 0.85, P<0.001).
  
  
  CONCLUSIONS
  Advanced age and comorbidities including previous myocardial infarction, previous stroke, chronic renal failure and pneumonia were independent risk factors for CS.
authors.affiliation: Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
authors.forename: Yu-sheng
authors.initials: YS
authors.lastname: Zhao
authors.forename: Guang-hua
authors.initials: GH
authors.lastname: Liu
authors.forename: Jia-yue
authors.initials: JY
authors.lastname: Li
authors.forename: Xing-li
authors.initials: XL
authors.lastname: Wu
authors.forename: Qiao
authors.initials: Q
authors.lastname: Xue
authors.forename: Lei
authors.initials: L
authors.lastname: Gao
authors.forename: Xue-dong
authors.initials: XD
authors.lastname: Yang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Xu
authors.forename: Ran
authors.initials: R
authors.lastname: Zhang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications*; D012189:Retrospective Studies; D012307:Risk Factors; D012770:Shock, Cardiogenic / Q000209:etiology*