title: Multiparametric multidetector computed tomography scanning on suspicion of hyperacute ischemic stroke: validating a standardized protocol.
abstract: Multidetector computed tomography (MDCT) scanning has enabled the early diagnosis of hyperacute brain ischemia. We aimed at validating a standardized protocol to read and report MDCT techniques in a series of adult patients. The inter-observer agreement among the trained examiners was tested, and their results were compared with a standard reading. No false positives were observed, and an almost perfect agreement (Kappa>0.81) was documented when the CT angiography (CTA) and cerebral perfusion CT (CPCT) map data were added to the noncontrast CT (NCCT) analysis. The inter-observer agreement was higher for highly trained readers, corroborating the need for specific training to interpret these modern techniques. The authors recommend adding CTA and CPCT to the NCCT analysis in order to clarify the global analysis of structural and hemodynamic brain abnormalities. Our structured report is suitable as a script for the reproducible analysis of the MDCT of patients on suspicion of ischemic stroke.
authors.affiliation: Division of Neuroradiology, Santa Casa de Misericórdia de São Paulo, São PauloSP, Brazil.
authors.forename: Felipe Torres
authors.initials: FT
authors.lastname: Pacheco
authors.forename: Antônio José da
authors.initials: AJ
authors.lastname: Rocha
authors.forename: Ingrid Aguiar
authors.initials: IA
authors.lastname: Littig
authors.forename: Antonio Carlos Martins Maia
authors.initials: AC
authors.lastname: Júnior
authors.forename: Rubens José
authors.initials: RJ
authors.lastname: Gagliardi
mesh_terms: D000208:Acute Disease; D000328:Adult; D002545:Brain Ischemia / Q000000981:diagnostic imaging*; D002533:Cerebral Angiography / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D061330:Multidetector Computed Tomography / Q000379:methods / Q000592:standards*; D015588:Observer Variation; D015203:Reproducibility of Results; D020521:Stroke / Q000000981:diagnostic imaging*