title: Fluorescent silver nanoclusters as DNA probes.
abstract: Fluorescent silver nanoclusters (few atoms, quantum sized) have attracted much attention as promising substitutes for conventional fluorophores. Due to their unique environmental sensitivities, new fluorescent probes have been developed based on silver nanoclusters for the sensitive and specific detection of DNA. In this review we present the recent discoveries of activatable and color-switchable properties of DNA-templated silver nanoclusters and discuss the strategies to use these new properties in DNA sensing.
authors.affiliation: Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712, USA.
authors.forename: Judy M
authors.initials: JM
authors.lastname: Obliosca
authors.forename: Cong
authors.initials: C
authors.lastname: Liu
authors.forename: Hsin-Chih
authors.initials: HC
authors.lastname: Yeh
mesh_terms: D004247:DNA / Q000032:analysis; D015342:DNA Probes / Q000737:chemistry*; D031541:Fluorescence Resonance Energy Transfer; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D009693:Nucleic Acid Hybridization; D020641:Polymorphism, Single Nucleotide; D012834:Silver / Q000737:chemistry*
chemical_list: D015342:DNA Probes; D012834:Silver; D004247:DNA