title: Pd(II)-catalyzed C-H iodination using molecular I2 as the sole oxidant.
abstract: Pd-catalyzed ortho-C-H iodination directed by a weakly coordinating amide auxiliary using I2 as the sole oxidant was developed. This reaction is compatible with a wide range of heterocycles including pyridines, imidazoles, oxazoles, thiazoles, isoxazoles, and pyrazoles.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.
authors.forename: Xiao-Chen
authors.initials: XC
authors.lastname: Wang
authors.forename: Yi
authors.initials: Y
authors.lastname: Hu
authors.forename: Samuel
authors.initials: S
authors.lastname: Bonacorsi
authors.forename: Yang
authors.initials: Y
authors.lastname: Hong
authors.forename: Richard
authors.initials: R
authors.lastname: Burrell
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu
mesh_terms: D002384:Catalysis; D006847:Hydrocarbons, Iodinated / Q000138:chemical synthesis* / Q000737:chemistry; D007455:Iodine / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D006847:Hydrocarbons, Iodinated; D009942:Organometallic Compounds; D016877:Oxidants; D010165:Palladium; D007455:Iodine