title: [Acute transverse myelitis after allogeneic bone marrow transplantation for acute lymphoblastic leukemia--a case report].
abstract: Transverse myelitis is an inflammatory disorder of the spinal cord that results in motor, sensory, and autonomic dysfunction. Herein, we describe a 40-year-old Japanese female who developed acute transverse myelitis (ATM) after an unrelated bone marrow transplantation for Philadelphia-positive acute lymphoblastic leukemia in molecular complete remission. Approximately 90 days after transplantation, she suffered from paresthesias, sphincter dysfunction, and lower extremity weakness. Spinal cord magnetic resonance imaging scan demonstrated findings consistent with ATM. The symptoms were resolved with the administration of steroids, followed by intravenous immunoglobulin therapy for a few sequelae. To the best of our knowledge, the presentation of ATM after hematopoietic stem cell transplantation is relatively rare. As the functional prognosis of ATM depends on prompt diagnosis and treatment, we consider that ATM should be included in the differential diagnosis of post-transplant myelopathies.
authors.affiliation: Dept. of Hematology, Osaka City University,
authors.forename: Masahiro
authors.initials: M
authors.lastname: Manabe
authors.forename: Mitsutaka
authors.initials: M
authors.lastname: Nishimoto
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Ito
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okamura
authors.forename: Masato
authors.initials: M
authors.lastname: Bingo
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yoshida
authors.forename: Atsushi
authors.initials: A
authors.lastname: Inoue
authors.forename: Mizuki
authors.initials: M
authors.lastname: Aimoto
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Hayashi
authors.forename: Hideo
authors.initials: H
authors.lastname: Koh
authors.forename: Takahiko
authors.initials: T
authors.lastname: Nakane
authors.forename: Mika
authors.initials: M
authors.lastname: Nakamae
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Terada
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Nakamae
authors.forename: Takafumi
authors.initials: T
authors.lastname: Nakao
authors.forename: Ki-Ryang
authors.initials: KR
authors.lastname: Koh
authors.forename: Manabu
authors.initials: M
authors.lastname: Hirai
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Nakao
authors.forename: Takahisa
authors.initials: T
authors.lastname: Yamane
authors.forename: Masayuki
authors.initials: M
authors.lastname: Hino
mesh_terms: D000208:Acute Disease; D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009188:Myelitis, Transverse / Q000209:etiology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000601:surgery*; D014184:Transplantation, Homologous