title: The potential for antimicrobials to adversely affect mental state.
abstract: This is a case report highlighting the influence that antimicrobials (clarithromycin in particular) can have on one's mental state. We discuss the case of a middle-aged woman who presented to an acute admissions unit under Irish Mental Health Act for involuntary admission because of concerns expressed by her family and general practitioner regarding a recent change in behaviour and onset of irritable mood. This lady was diagnosed with an episode of mania that was thought to be precipitated by a combination of psychosocial stressors, recent discontinuation of psychotropic medication and complicated by a recent course of clarithromycin.
authors.affiliation: Department of Psychiatry, Galway University Hospital, Galway, Ireland. lelally@yahoo.ie
authors.forename: Leona
authors.initials: L
authors.lastname: Lally
authors.forename: Laura
authors.initials: L
authors.lastname: Mannion
mesh_terms: D000890:Anti-Infective Agents / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000139:chemically induced* / Q000175:diagnosis; D002939:Ciprofloxacin / Q000031:analogs & derivatives; D017291:Clarithromycin / Q000009:adverse effects*; D003134:Commitment of Persons with Psychiatric Disorders; D003221:Confusion / Q000139:chemically induced; D005260:Female; D006801:Humans; D008875:Middle Aged; D015609:Organotechnetium Compounds
chemical_list: D000890:Anti-Infective Agents; D015609:Organotechnetium Compounds; C431804:Technetium Tc 99m ciprofloxacin; D002939:Ciprofloxacin; D017291:Clarithromycin