title: Chronic primary central nervous system histoplasmosis in a healthy child with intermittent neurological manifestations.
abstract: Meningitis is an unusual clinical manifestation of Histoplasma capsulatum infection in nonimmunosuppressed children. We report a previously healthy 6-year-old boy with primary, chronic histoplasma meningitis and magnetic resonance imaging findings consistent with demyelinating disease presenting with brief, intermittent neurological manifestations for 7 months before diagnosis.
authors.affiliation: Department of Pediatrics, Infectious Diseases Division, Vanderbilt University, Nashville, TN 37232, USA.
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Schuster
authors.forename: Curtis A
authors.initials: CA
authors.lastname: Wushensky
authors.forename: M Cecilia
authors.initials: MC
authors.lastname: Di Pentima
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging; D002648:Child; D002908:Chronic Disease; D006658:Histoplasma / Q000302:isolation & purification*; D006660:Histoplasmosis / Q000175:diagnosis* / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D016921:Meningitis, Fungal / Q000175:diagnosis* / Q000473:pathology*; D011859:Radiography; D012008:Recurrence