title: [Chemical constituents of surface layer of Poria cocos and their pharmacological properties (I)].
abstract: The surface layer of the sclerotia of Poria cocos, named Fu-Ling-Pi, is used as a diuretic in traditional Chinese medicine to treat edema and urinary dysfunction. Recent studies have showed that the triterpenes (lanostane and 3,4-secolanostane skeletons) and polysaccharides (beta-pachyman) are the main components of Fu-Ling-Pi and they exhibited various biological activities, such as anti-tumor, antibacterial and antioxidant, etc. This review was focused on the chemistry, pharmacology, and clinical uses of this drug and it may provide scientific foundation for further development and utilization of Fulingpi.
authors.affiliation: Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, the College of Life Sciences, Northwest University, Xi'an 710069, China. fengyalong2012@163.com
authors.forename: Ya-Long
authors.initials: YL
authors.lastname: Feng
authors.forename: Ying-Yong
authors.initials: YY
authors.lastname: Zhao
authors.forename: Fan
authors.initials: F
authors.lastname: Ding
authors.forename: Zhi-Hui
authors.initials: ZH
authors.lastname: Xi
authors.forename: Ting
authors.initials: T
authors.lastname: Tian
authors.forename: Fan
authors.initials: F
authors.lastname: Zhou
authors.forename: Xiao
authors.initials: X
authors.lastname: Du
authors.forename: Dan-Qian
authors.initials: DQ
authors.lastname: Chen
authors.forename: Feng
authors.initials: F
authors.lastname: Wei
authors.forename: Xian-Long
authors.initials: XL
authors.lastname: Cheng
authors.forename: Rui-Chao
authors.initials: RC
authors.lastname: Lin
mesh_terms: D000818:Animals; D004358:Drug Therapy; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D015394:Molecular Structure; D055441:Poria / Q000737:chemistry*; D000070660:Wolfiporia
chemical_list: D004365:Drugs, Chinese Herbal