title: Evaluation of several novel alkynols, alkenols, and selected host odor blends as attractants to female Aedes albopictus and Culex quinquefasciatus.
abstract: The compound 1-octen-3-ol is a strong attractant for some mosquito species. Based on chemical structure, this may be due to a terminal site of unsaturation or high electron density, a structural capability for hydrogen bonding, e.g., -OH, -NH2, NHR, NR2, etc., a saturated hydrocarbon chain of a certain minimum length, and a certain relative distance between the region of high electron density and the alcohol (or other hydrogen-bonding) functional group. Based on this hypothesis, 4 novel alkynol (triple-bonded) analogs were synthesized and evaluated alone or in combination with acetone and dimethyl disulfide, and with and without carbon dioxide in Mosquito Magnet-X suction traps. Attraction of laboratory-reared adult Aedes albopictus and Culex quinquefasciatus to these analogs and combinations was compared to 1-octen-3-ol as a standard in semi-field trials. For both species none of the alkynols, with and without carbon dioxide or acetone and dimethyl disulfide, were significantly different from 1-octen-3-ol. The compounds 2-octyn-4-ol and 2-nonyn-4-ol alone and with carbon dioxide suppressed Cx. quinquefasciatus collections. An additional 6 alkenol (double-bonded) analogs were tested in mixtures with 3-n-propylphenol and 4-methylphenol in a ratio of 4:1:8, respectively. Using the same trapping methods, Cx. quinquefasciatus catches containing 3-decen-1-ol were increased nearly 3-fold when combined with carbon dioxide. Aedes albopictus collections in traps with the 3-decen-1-ol/phenol mixture and carbon dioxide were significantly greater than similar traps with 1-octen-3-ol. Traps baited with the phenol blends that incorporated (Z)-3-nonen-1-ol, (Z)-8-nonen-3-ol, or 1-octen-3-ol were considerably suppressed in the presence of carbon dioxide.
authors.affiliation: John A. Mulrennan, Sr. Public Health Entomology Research and Education Center, College of Engineering Sciences, Technology and Agriculture, Florida A&M University, 4000 Frankford Avenue, Panama City, FL 32405, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Cilek
authors.forename: C O
authors.initials: CO
authors.lastname: Ikediobi
authors.forename: C F
authors.initials: CF
authors.lastname: Hallmon
authors.forename: R
authors.initials: R
authors.lastname: Johnson
authors.forename: O
authors.initials: O
authors.lastname: Okungbowa
authors.forename: E N
authors.initials: EN
authors.lastname: Onyeozili
authors.forename: L M
authors.initials: LM
authors.lastname: Khalil
authors.forename: L
authors.initials: L
authors.lastname: Ayuk-Takem
authors.forename: L M
authors.initials: LM
authors.lastname: Latinwo
authors.forename: U R
authors.initials: UR
authors.lastname: Bernier
mesh_terms: D000330:Aedes / Q000187:drug effects*; D000438:Alcohols / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001681:Biological Assay; D003465:Culex / Q000187:drug effects*; D005260:Female; D015394:Molecular Structure; D010675:Pheromones / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000438:Alcohols; D010675:Pheromones