title: Boron nitride nanotubes functionalized with mesoporous silica for intracellular delivery of chemotherapy drugs.
abstract: Boron nitride nanotube (BNNT)@mesoporous silica hybrids with controllable surface zeta potential were fabricated for intracellular delivery of doxorubicin. The materials showed higher suspension ability, doxorubicin intracellular endocytosis efficiency, and LNcap prostate cancer cell killing ability compared with naked BNNTs.
authors.affiliation: World Premier International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), Namiki 1-1, Tsukuba, Ibaraki 305-0044, Japan. LI.Xia@nims.go.jp
authors.forename: Xia
authors.initials: X
authors.lastname: Li
authors.forename: Chunyi
authors.initials: C
authors.lastname: Zhi
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Hanagata
authors.forename: Maho
authors.initials: M
authors.lastname: Yamaguchi
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Bando
authors.forename: Dmitri
authors.initials: D
authors.lastname: Golberg
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000737:chemistry; D001896:Boron Compounds / Q000737:chemistry*; D002478:Cells, Cultured; D004317:Doxorubicin / Q000008:administration & dosage; D016503:Drug Delivery Systems; D006801:Humans; D008297:Male; D043942:Nanotubes / Q000737:chemistry*; D016062:Porosity; D011471:Prostatic Neoplasms / Q000188:drug therapy; D012822:Silicon Dioxide / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000970:Antineoplastic Agents; D001896:Boron Compounds; C017282:boron nitride; D012822:Silicon Dioxide; D004317:Doxorubicin