title: Ear, nose, and throat involvement in Egyptian patients with pemphigus vulgaris: a step towards a better management.
abstract: BACKGROUND
  The frequency of ear, nose, and throat (ENT) involvement in pemphigus vulgaris (PV) is not clear; thereby, the importance of setting routine ENT examination for patients with PV could not be deduced.
  
  
  OBJECTIVE
  Determine the prevalence of ENT involvement in patients with PV in Egypt; to modify the routine protocol and achieve a step towards better management.
  
  
  METHODS
  Thirty-four patients with PV were included. Patients were asked about ENT symptomatology and evaluated for ENT manifestations.
  
  
  RESULTS
  Twenty-five patients complained from ENT symptoms (74%). The pharyngeal/laryngeal-related symptoms were the most common. Eighty-two percent of patients had positive endoscopic findings. The most common were pharyngeal/laryngeal (76.5%). In total, the positive endoscopic findings superseded the positive symptomatic findings. More severe involvement was documented in non-smoking patients (P < 0.05).
  
  
  CONCLUSIONS
  Full ENT examination as a routine for all patients with PV could be of great value, as it would lead to more accurate diagnosis, therefore improved management.
authors.affiliation: Departments of Dermatology and Otorhinolaryngology, Faculty of Medicine, Cairo University, Cairo, Egypt.
authors.forename: Marwa Mohamed
authors.initials: MM
authors.lastname: Fawzy
authors.forename: Rehab A
authors.initials: RA
authors.lastname: Hegazy
authors.forename: Ahmed F
authors.initials: AF
authors.lastname: Abdel Fattah
mesh_terms: D000328:Adult; D000368:Aged; D004427:Ear Diseases / Q000453:epidemiology* / Q000473:pathology; D004534:Egypt / Q000453:epidemiology; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009668:Nose Diseases / Q000453:epidemiology* / Q000473:pathology; D010392:Pemphigus / Q000453:epidemiology* / Q000473:pathology; D010608:Pharyngeal Diseases / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence; D012720:Severity of Illness Index; D055815:Young Adult