title: First imported case of skin infection caused by PVL-positive ST30 community-associated methicillin-resistant Staphylococcus aureus clone in a returning Korean traveler from the Philippines.
abstract: Although pandemic community-associated (CA-) methicillin-resistant Staphylococcus aureus (MRSA) ST30 clone has successfully spread into many Asian countries, there has been no case in Korea. We report the first imported case of infection caused by this clone in a Korean traveler returning from the Philippines. A previously healthy 30-yr-old Korean woman developed a buttock carbuncle while traveling in the Philippines. After coming back to Korea, oral cephalosporin was given by a primary physician without any improvement. Abscess was drained and MRSA strain isolated from her carbuncle was molecularly characterized and it was confirmed as ST30-MRSA-IV. She was successfully treated with vancomycin and surgery. Frequent international travel and migration have increased the risk of international spread of CA-MRSA clones. The efforts to understand the changing epidemiology of CA-MRSA should be continued, and we should raise suspicion of CA-MRSA infection in travelers with skin infections returning from CA-MRSA-endemic countries.
authors.affiliation: Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Jaehoon
authors.initials: J
authors.lastname: Ko
authors.forename: Doo Ryeon
authors.initials: DR
authors.lastname: Chung
authors.forename: So Yeon
authors.initials: SY
authors.lastname: Park
authors.forename: Jin Yang
authors.initials: JY
authors.lastname: Baek
authors.forename: So Hyun
authors.initials: SH
authors.lastname: Kim
authors.forename: Cheol-In
authors.initials: CI
authors.lastname: Kang
authors.forename: Kyong Ran
authors.initials: KR
authors.lastname: Peck
authors.forename: Nam Yong
authors.initials: NY
authors.lastname: Lee
authors.forename: Jae-Hoon
authors.initials: JH
authors.lastname: Song
mesh_terms: D000328:Adult; D001427:Bacterial Toxins / Q000378:metabolism; D002270:Carbuncle / Q000382:microbiology; D002511:Cephalosporins / Q000627:therapeutic use; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000382:microbiology; D005098:Exotoxins / Q000378:metabolism; D005260:Female; D006801:Humans; D007956:Leukocidins / Q000378:metabolism; D016106:Methicillin Resistance; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D010679:Philippines; D056910:Republic of Korea; D013207:Staphylococcal Skin Infections / Q000188:drug therapy* / Q000601:surgery; D014195:Travel; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D001427:Bacterial Toxins; D002511:Cephalosporins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D014640:Vancomycin
keywords: Carbuncle; Community-Acquired Infections; Methicillin Resistance; Staphylococcus aureus; Travel