title: Food allergy: management, diagnosis and treatment strategies.
abstract: Food allergy is an increasing problem in western countries, with strict avoidance being the only available reliable treatment. However, accidental ingestion can occur and anaphylactic reactions still happen. In recent years, many efforts have been made to better understand the humoral and cellular mechanisms involved in food allergy, and to improve the strategies for diagnosis and treatment. This review focuses on IgE-mediated food hypersensitivity and provides an overview of the diagnostic strategies and treatment advances. Specific immunotherapy, including different routes of administration and allergen sources, such as natural, recombinant and T-cell epitopes, are analyzed in detail. Other treatments such as anti-IgE monoclonal antibody therapy, adjuvant therapy and Chinese herbs will also be described.
authors.affiliation: Research Laboratory for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain.
authors.forename: Enrique
authors.initials: E
authors.lastname: Gómez
authors.forename: Cristobalina
authors.initials: C
authors.lastname: Mayorga
authors.forename: Francisca
authors.initials: F
authors.lastname: Gómez
authors.forename: Ana Belen
authors.initials: AB
authors.lastname: Blázquez
authors.forename: Araceli
authors.initials: A
authors.lastname: Díaz-Perales
authors.forename: Miguel
authors.initials: M
authors.lastname: Blanca
authors.forename: María José
authors.initials: MJ
authors.lastname: Torres
mesh_terms: D000485:Allergens / Q000276:immunology / Q000627:therapeutic use*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D003888:Desensitization, Immunologic / Q000379:methods* / Q000639:trends; D003937:Diagnosis, Differential; D004333:Drug Administration Routes; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D018984:Epitopes, T-Lymphocyte / Q000276:immunology; D005512:Food Hypersensitivity / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D011994:Recombinant Proteins / Q000276:immunology
chemical_list: D000485:Allergens; D000911:Antibodies, Monoclonal; D004365:Drugs, Chinese Herbal; D018984:Epitopes, T-Lymphocyte; D011994:Recombinant Proteins; D007073:Immunoglobulin E