title: Surface molecular imprinting onto silver microspheres for surface enhanced Raman scattering applications.
abstract: A simple route for the synthesis of core-shell Ag-molecularly imprinted polymer (Ag@MIP) hybrid was proposed. Silver microspheres were first fabricated by the acid-directed self-assembly technique, and then they were modified using coupling agent, core-shell Ag@MIP hybrid were finally obtained through surface molecular imprinting technique. The morphology and structure of the resulting hybrid were characterized by X-ray diffraction, energy dispersive spectroscopy, transmission and scanning electron microscopy, and Fourier transform infrared spectroscopy. The obtained Ag@MIP substrate is extremely high surface enhanced Raman scattering (SERS) activity toward the target molecule 4-mercaptobenzoic acid (4-MBA)，and exhibits a 10(-15)M detection limit. The SERS signals of 4-MBA show good reproducibility and selectivity. A possible mechanism for our SERS enhancement was briefly discussed using a molecularly imprinting "gate effect" model. Our experimental results show that the Ag@MIP hybrid as SERS platform is potential for ultrasensitive sensing and analytical applications.
authors.affiliation: School of Chemistry, Jilin Normal University, Siping 136000, China. Electronic address: aaaa2139@163.com.
authors.forename: Limin
authors.initials: L
authors.lastname: Chang
authors.forename: Yan
authors.initials: Y
authors.lastname: Ding
authors.forename: Xin
authors.initials: X
authors.lastname: Li
mesh_terms: D001565:Benzoates / Q000032:analysis*; D057230:Limit of Detection; D008863:Microspheres; D054802:Molecular Imprinting; D012834:Silver / Q000737:chemistry*; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013438:Sulfhydryl Compounds / Q000032:analysis*
chemical_list: D001565:Benzoates; D013438:Sulfhydryl Compounds; C013594:4-mercaptobenzoate; D012834:Silver
keywords: 4-Mercaptobenzoic acid; Molecularly imprinted polymer; Silver; Surface enhanced Raman scattering