title: InBr3-mediated one-pot synthesis of 2-(polyhydroxylatedalkyl)-N-aryl-/-alkylpyrroles from 1,2-cyclopropa-3-pyranone and amines.
abstract: An efficient one-pot synthesis of polyhydroxyalkyl-substituted pyrroles from 1,2-cyclopropa-3-pyranones with primary amines is reported. With 10% of InBr3 as the catalyst, both aryl- and alkylamines as well as various 1,2-cyclopropa-3-pyranones are well tolerated. This method is highly appealing because of its one-pot process, mild reaction conditions, substrate simplicity, and broad substrate scope.
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, China.
authors.forename: Pingyuan
authors.initials: P
authors.lastname: Wang
authors.forename: Shanshan
authors.initials: S
authors.lastname: Song
authors.forename: Zehong
authors.initials: Z
authors.lastname: Miao
authors.forename: Guangfu
authors.initials: G
authors.lastname: Yang
authors.forename: Ao
authors.initials: A
authors.lastname: Zhang
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D007204:Indium / Q000737:chemistry*; D015394:Molecular Structure; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D000588:Amines; D011753:Pyrones; D011758:Pyrroles; C530781:indium bromide; D007204:Indium