title: Methicillin-resistant Staphylococcus aureus antibiotic resistance and virulence.
abstract: Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most critical causes of healthcare-related or community-related infections. Resistance to most β-lactam antibiotics makes MRSA a big threat to clinical treatment. Utilization of low efficiency antibiotics such as vancomycin and teicoplanin makes new choices for therapies. Recently, much researchhas shed light on relevance between genetic mutations of MRSA and clinical characteristics such as antibiotic resistance, and virulence. These findings could contribute to development of novel antibiotics and vaccines.
authors.affiliation: Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
authors.forename: Jufeng
authors.initials: J
authors.lastname: Xia
authors.forename: Jianjun
authors.initials: J
authors.lastname: Gao
authors.forename: Norihiro
authors.initials: N
authors.lastname: Kokudo
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Wei
authors.initials: W
authors.lastname: Tang
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity*; D009154:Mutation; D014774:Virulence / Q000235:genetics / Q000502:physiology*
chemical_list: D000900:Anti-Bacterial Agents