title: Hydrogen bond templated 1:1 macrocyclization through an olefin metathesis/hydrogenation sequence.
abstract: The construction of pyridine-containing macrocyclic architectures using a nonmetallic template is described. 4,6-Dichlororesorcinol was used as an exotemplate to self-organize two aza-heterocyclic units by OH···N hydrogen bonds. Subsequent sequential double olefin metathesis/hydrogenation reactions employing a single ruthenium-alkylidene precatalyst open access to macrocyclic molecules.
authors.affiliation: Chimie et Photonique Moléculaires, Institut des Sciences Chimiques de Rennes, UMR 6226 CNRS - Université de Rennes 1, Campus de Beaulieu, CS 74205, 35042 Rennes Cedex, France.
authors.forename: Andrada Stefania
authors.initials: AS
authors.lastname: Trita
authors.forename: Thierry
authors.initials: T
authors.lastname: Roisnel
authors.forename: Florence
authors.initials: F
authors.lastname: Mongin
authors.forename: Floris
authors.initials: F
authors.lastname: Chevallier
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006860:Hydrogen Bonding; D006865:Hydrogenation; D047028:Macrocyclic Compounds / Q000737:chemistry*; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D012118:Resorcinols / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D000475:Alkenes; D047028:Macrocyclic Compounds; D011725:Pyridines; D012118:Resorcinols; D012428:Ruthenium