title: Iron-catalyzed trifluoromethylation with concomitant C-C bond formation via 1,2-migration of an aryl group.
abstract: Iron-catalyzed trifluoromethylation with concomitant 1,2-migration of an aryl group starting from diaryl allyl alcohol was achieved under mild conditions. This reaction system affords α-substituted-β-trifluoromethyl carbonyl compounds in high efficiency. In the case of substrates bearing different aryl groups, selective migration was observed.
authors.affiliation: Synthetic Organic Chemistry Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Egami
authors.forename: Ryo
authors.initials: R
authors.lastname: Shimizu
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Usui
authors.forename: Mikiko
authors.initials: M
authors.lastname: Sodeoka
mesh_terms: D002384:Catalysis; D005461:Fluorine / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D008745:Methylation; D015394:Molecular Structure
chemical_list: D005461:Fluorine; D007501:Iron