title: Effects of animal liver and bile extracts on biochemical values of rat ethanol-induced fatty liver.
abstract: The purposes of this study were to assess the improvement of fatty liver induced by ethanol with animal liver and bile extracts. This research aimed to increase the economic values of animal liver and bile extracts and used these to reduce damage of ethanol-induced fatty liver. Extracts came from animal liver and bile, including pig bile powder, pig liver extract, a mixture of pig bile powder and pig liver extract, chicken bile powder, chicken liver extract, and a mixture of chicken bile powder and chicken liver extract, and these were fed to Long-Evans rats. The results showed that rats fed ethanol for long terms could increase values of aspartate transaminase, cholesterol, γ-glutamy-transferase and alkaline phosphatase. Pig bile powder could decrease the values of aspartate transaminase, cholesterol and γ-glutamy-transferase. The significances also decreased on aspartate transaminase, γ-glutamy-transferase and aspartate transaminase, which were carried out with the pig liver extract treatment. These results suggest pig bile and liver extracts have high potential to improve rats' ethanol-induced fatty liver with serum biochemical parameters.
authors.affiliation: Animal Products Processing Division, Livestock Research Institute, Council of Agriculture, Tainan, Taiwan.
authors.forename: Tien-Chun
authors.initials: TC
authors.lastname: Wan
authors.forename: Yu-Tse
authors.initials: YT
authors.lastname: Liu
authors.forename: Lan-Tyi
authors.initials: LT
authors.lastname: Duann
authors.forename: Kuo-Hui
authors.initials: KH
authors.lastname: Yu
authors.forename: Chih-Ming
authors.initials: CM
authors.lastname: Chen
authors.forename: Liang-Chuan
authors.initials: LC
authors.lastname: Lin
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Sakata
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001646:Bile / Q000737:chemistry*; D002645:Chickens; D002784:Cholesterol / Q000097:blood; D005235:Fatty Liver, Alcoholic / Q000097:blood / Q000628:therapy*; D008099:Liver / Q000737:chemistry*; D008297:Male; D020318:Rats, Long-Evans; D013552:Swine; D014020:Tissue Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D014020:Tissue Extracts; D002784:Cholesterol; D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase
keywords: bile; ethanol-induced fatty liver; extract; liver