title: GnRH analogues in the prevention of ovarian hyperstimulation syndrome.
abstract: The GnRH analogue (agonist and antagonist GnRH) changed ovarian stimulation. On the one hand, it improved chances of pregnancy to obtain more oocytes and better embryos. This leads to an ovarian hyper-response, which can be complicated by the ovarian hyperstimulation syndrome (OHSS). On the other hand, the GnRH analogue can prevent the incidence of OHSS: GnRH antagonist protocols, GnRH agonist for triggering final oocyte maturation, either together or separately, coasting, and the GnRH analogue may prove useful for avoiding OHSS in high-risk patients. We review these topics in this article.
authors.affiliation: Department of Reproduction, IVI-Valencia, Plaza de la Policia Local, Valencia, Spain.
authors.forename: Pilar
authors.initials: P
authors.lastname: Alama
authors.forename: Jose
authors.initials: J
authors.lastname: Bellver
authors.forename: Carmen
authors.initials: C
authors.lastname: Vidal
authors.forename: Juan
authors.initials: J
authors.lastname: Giles
keywords: GnRH Agonist; GnRH Antagonist; Ovarian Hyperstimulation Syndrome; Ovarian Stimulation; Prevention