title: Acute respiratory distress syndrome: new definition, current and future therapeutic options.
abstract: Since acute respiratory distress syndrome (ARDS) was first described in 1967 there has been large number of studies addressing its pathogenesis and therapies. Despite this intense research activity, there are very few effective therapies for ARDS other than the use of lung protection strategies. This lack of therapeutic modalities is not only related to the complex pathogenesis of this syndrome but also the insensitive and nonspecific diagnostic criteria to diagnose ARDS. This review article will summarize the key features of the new definition of ARDS, and provide a brief overview of innovative therapeutic options that are being assessed in the management of ARDS.
authors.affiliation: Department of Anesthesia and Critical Care Medicine, University of Turin, Azienda Ospedaliera Città della Salute e della Scienza di Torino, Italy;
authors.forename: Vito
authors.initials: V
authors.lastname: Fanelli
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Vlachou
authors.forename: Shirin
authors.initials: S
authors.lastname: Ghannadian
authors.forename: Umberto
authors.initials: U
authors.lastname: Simonetti
authors.forename: Arthur S
authors.initials: AS
authors.lastname: Slutsky
authors.forename: Haibo
authors.initials: H
authors.lastname: Zhang
keywords: Acute respiratory distress syndrome (ARDS); pathogenesis; therapeutic options