title: Neurobiological factors as predictors of cognitive-behavioral therapy outcome in individuals with antisocial behavior: a review of the literature.
abstract: This review focuses on the predictive value of neurobiological factors in relation to cognitive-behavioral therapy outcome among individuals with antisocial behavior. Ten relevant studies were found. Although the literature on this topic is scarce and diverse, it appears that specific neurobiological characteristics, such as physiological arousal levels, can predict treatment outcome. The predictive value of neurobiological factors is important as it could give more insight into the causes of variability in treatment outcome among individuals with antisocial behavior. Furthermore, results can contribute to improvement in current treatment selection procedures and to the development of alternative treatment options.
authors.affiliation: The Netherlands Institute for the Study of Crime and Law Enforcement (NSCR), Amsterdam, The Netherlands Research and Documentation Centre (WODC), Ministry of Security and Justice, Den Haag, The Netherlands LCornet@nscr.nl.
authors.forename: Liza J M
authors.initials: LJ
authors.lastname: Cornet
authors.affiliation: Research and Documentation Centre (WODC), Ministry of Security and Justice, Den Haag, The Netherlands.
authors.forename: Catharina H
authors.initials: CH
authors.lastname: de Kogel
authors.affiliation: Altrecht, Den Dolder, The Netherlands Radboud University, Nijmegen, The Netherlands.
authors.forename: Henk L I
authors.initials: HL
authors.lastname: Nijman
authors.affiliation: Departments of Criminology, Psychiatry, and Psychology, University of Pennsylvania, Philadelphia, USA.
authors.forename: Adrian
authors.initials: A
authors.lastname: Raine
authors.affiliation: The Netherlands Institute for the Study of Crime and Law Enforcement (NSCR), Amsterdam, The Netherlands Faculty of Law, VU University, Amsterdam, The Netherlands.
authors.forename: Peter H
authors.initials: PH
authors.lastname: van der Laan
mesh_terms: D000293:Adolescent; D000328:Adult; D000987:Antisocial Personality Disorder / Q000503:physiopathology* / Q000523:psychology / Q000628:therapy; D001143:Arousal / Q000502:physiology*; D002648:Child; D015928:Cognitive Behavioral Therapy; D005625:Frontal Lobe / Q000503:physiopathology; D006728:Hormones / Q000097:blood; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology; D010913:Pituitary-Adrenal System / Q000503:physiopathology; D017397:Prefrontal Cortex / Q000503:physiopathology; D011379:Prognosis; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D006728:Hormones
keywords: antisocial behavior; cognitive–behavioral therapy; neurobiology