title: [Factors associated with quality of life in patients in renal replacement therapy in Brazil].
abstract: End-stage renal disease (ESRD) is a serious public health problem. The study of the impact of renal replacement therapy (RRT) in quality of life (QoL) has become increasingly important. The aim of this study was to evaluate the QoL of patients on RRT and associated factors. 3036 patients on RRT in Brazil were interviewed in relation to socioeconomic, demographic, clinical and QoL aspects. Patients were randomly selected after a cluster sampling process on two levels: health services and patients. QoL was measured by Eq5D. The instrument allows the indirect measurement of QoL and utility calculation, in addition to the direct measurement of QoL by a visual analog scale (VAS). It was observed that transplant patients have better QoL and that the most prejudicial aspects are pain/discomfort and anxiety/depression. The main factors associated with QOL are age, female gender, variables associated with the clinical condition of the patient such as the need for hospitalization and the presence of comorbidities, social class and variables associated with the health service use. The correlation between VAS and utility calculated was moderate and the 5 Eq5D questions explain 43% of the variability of VAS. The calculated utility can be used in cost-utility analysis.
authors.affiliation: Departamento de Farmácia Social, Universidade Federal de Minas Gerais, R. Silvianopolis 425/302, Bairro Santa Tereza, Belo Horizonte, MG. jualvares@gmail.com
authors.forename: Juliana
authors.initials: J
authors.lastname: Alvares
authors.forename: Alessandra Maciel
authors.initials: AM
authors.lastname: Almeida
authors.forename: Daniele Araujo Campos
authors.initials: DA
authors.lastname: Szuster
authors.forename: Isabel Cristina
authors.initials: IC
authors.lastname: Gomes
authors.forename: Eli Iola Gurgel
authors.initials: EI
authors.lastname: Andrade
authors.forename: Francisco de Assis
authors.initials: Fde A
authors.lastname: Acurcio
authors.forename: Mariângela Leal
authors.initials: ML
authors.lastname: Cherchiglia
mesh_terms: D001938:Brazil; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D017582:Renal Replacement Therapy