title: Dynamics of Parecoxib or Meloxicam effect on acute postoperative pain after orthopedic surgical interventions: comparative study in hospitalized women and men.
abstract: The dynamics of Parecoxib or Meloxicam analgesic effect on acute postoperative pain was studied in 48 patients (22 female and 26 male) sustaining arthroprosthetic (Parecoxib analgesia) or arthroscopic (Meloxicam analgesia) orthopedic surgery. The results show higher postoperative pain and slower dynamics of Parecoxib and Meloxicam analgesia in women than in men, which necessitates supplementation of the applied analgesic medication in the female patients.
authors.affiliation: Clinic of Orthopedics and Reconstructive Surgery, Military Medical Academy, Sofia.
authors.forename: P
authors.initials: P
authors.lastname: Kraevsky
authors.forename: L
authors.initials: L
authors.lastname: Kasakov
authors.forename: M
authors.initials: M
authors.lastname: Vlaskovska
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000698:Analgesia; D000700:Analgesics / Q000627:therapeutic use*; D052246:Cyclooxygenase 2 Inhibitors / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007555:Isoxazoles / Q000627:therapeutic use*; D008297:Male; D000077239:Meloxicam; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000009:adverse effects; D010149:Postoperative Pain / Q000188:drug therapy* / Q000209:etiology; D013843:Thiazines / Q000627:therapeutic use*; D013844:Thiazoles / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D000700:Analgesics; D052246:Cyclooxygenase 2 Inhibitors; D007555:Isoxazoles; D013843:Thiazines; D013844:Thiazoles; C409945:parecoxib; D000077239:Meloxicam