title: Exploring the genetic basis of stroke. Spanish stroke genetics consortium.
abstract: This article provides an overview of stroke genetics studies ranging from the candidate gene approach to more recent studies by the genome wide association. It highlights the complexity of stroke owing to its different aetiopathogenic mechanisms, the difficulties in studying its genetic component, and the solutions provided to date. The study emphasises the importance of cooperation between the different centres, whether this takes places occasionally or through the creation of lasting consortiums. This strategy is currently essential to the completion of high-quality scientific studies that allow researchers to gain a better knowledge of the genetic component of stroke as it relates to aetiology, treatment, and prevention.
authors.affiliation: Grupo de Investigación Neurovascular, Departamento de Neurología, IMIM-Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, España. Electronic address: 96714@parcdesalutmar.cat.
authors.forename: E
authors.initials: E
authors.lastname: Giralt-Steinhauer
authors.affiliation: Grupo de Investigación Neurovascular, Departamento de Neurología, IMIM-Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Jiménez-Conde
authors.affiliation: Grupo de Investigación Neurovascular, Departamento de Neurología, IMIM-Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: C
authors.initials: C
authors.lastname: Soriano Tárraga
authors.affiliation: Grupo de Investigación Neurovascular, Departamento de Neurología, IMIM-Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: M
authors.initials: M
authors.lastname: Mola
authors.affiliation: Grupo de Investigación Neurovascular, Departamento de Neurología, IMIM-Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez-Campello
authors.affiliation: Grupo de Investigación Neurovascular, Departamento de Neurología, IMIM-Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: E
authors.initials: E
authors.lastname: Cuadrado-Godia
authors.affiliation: Grupo de Investigación Neurovascular, Departamento de Neurología, IMIM-Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: A
authors.initials: A
authors.lastname: Ois
authors.affiliation: Laboratorio de Investigación Neurovascular, Institut de Recerca, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: I
authors.initials: I
authors.lastname: Fernández-Cádenas
authors.affiliation: Laboratorio de Investigación Neurovascular, Institut de Recerca, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: C
authors.initials: C
authors.lastname: Carrera
authors.affiliation: Laboratorio de Investigación Neurovascular, Institut de Recerca, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Montaner
authors.affiliation: Departamento de Neurología, Hospital Universitari Son Espases, Mallorca, Baleares, España.
authors.forename: R M
authors.initials: RM
authors.lastname: Díaz Navarro
authors.affiliation: Departamento de Neurología, Hospital Universitari Son Espases, Mallorca, Baleares, España.
authors.forename: C
authors.initials: C
authors.lastname: Vives-Bauzá
authors.affiliation: Grupo de Investigación Neurovascular, Departamento de Neurología, IMIM-Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Roquer
mesh_terms: D044127:Epigenesis, Genetic; D020022:Genetic Predisposition to Disease; D055106:Genome-Wide Association Study; D006801:Humans; D020641:Polymorphism, Single Nucleotide; D012307:Risk Factors; D020521:Stroke / Q000235:genetics*
keywords: Asociación; Association; Consorcio; Consortium; Factores de riesgo genético; Genetic risk factors; Genetics; Genética; Ictus; Predicción; Prediction; Stroke