title: First case of Mycobacterium tuberculosis transmission by heart transplantation from donor to recipient.
abstract: We report the first documented case of a Mycobacterium tuberculosis transmission by an orthotopic heart transplantation from the donor to the recipient. Mycobacterium tuberculosis positive blood culture showed systemic prevalence of the Mycobacteria, however, prophylactic therapy was able to prevent a clinical manifestation of tuberculosis in the recipient.
authors.affiliation: Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Germany. Electronic address: jweile@hdz-nrw.de.
authors.forename: Jan
authors.initials: J
authors.lastname: Weile
authors.forename: Holm
authors.initials: H
authors.lastname: Eickmeyer
authors.forename: Jens
authors.initials: J
authors.lastname: Dreier
authors.forename: Michael
authors.initials: M
authors.lastname: Liebke
authors.forename: Uwe
authors.initials: U
authors.lastname: Fuchs
authors.forename: Johann-Wolfgang
authors.initials: JW
authors.lastname: Wittke
authors.forename: Elvira
authors.initials: E
authors.lastname: Richter
authors.forename: Jan
authors.initials: J
authors.lastname: Gummert
authors.forename: Cornelius
authors.initials: C
authors.lastname: Knabbe
authors.forename: Uwe
authors.initials: U
authors.lastname: Schulz
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D018890:Chemoprevention / Q000379:methods*; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D016896:Treatment Outcome; D014376:Tuberculosis / Q000517:prevention & control* / Q000635:transmission*
chemical_list: D000995:Antitubercular Agents
keywords: Donor; Heart transplantation; Recipient; Transmission; Tuberculosis