title: Highly efficient aminocarbonylation of iodoarenes at atmospheric pressure catalyzed by a robust acenaphthoimidazolyidene allylic palladium complex.
abstract: A robust allylic palladium-NHC complex was developed and exhibited extremely high catalytic activity toward aminocarbonylation of various (hetero)aryl iodides under atmospheric carbon monoxide pressure, in which a broad range of secondary and primary amines were well tolerated. In addition, the concise synthesis of an anticancer drug tamibarotene was accomplished even in a gram scale, further highlighting the practical applicability of the protocol.
authors.affiliation: Department of Chemistry, Fudan University, 220 Handan Road, 200433, Shanghai, China.
authors.forename: Weiwei
authors.initials: W
authors.lastname: Fang
authors.forename: Qinyue
authors.initials: Q
authors.lastname: Deng
authors.forename: Mizhi
authors.initials: M
authors.lastname: Xu
authors.forename: Tao
authors.initials: T
authors.lastname: Tu