title: An efficient biomimetic coating methodology for a prosthetic alloy.
abstract: The combination of the load-bearing metallic implants with the bioactive materials in the design of synthetic implants is an important aspect in the biomaterials research. Biomimetic coating of bioinert alloys with calcium phosphate phases provides a good alternative to the prerequisite for the continual replacement of implants because of the failure of bone-implant integration. We attempted to accelerate the biomimetic coating process of stainless steel alloy (316L) with biomimetic apatite. In addition, we investigated the incorporation of functioning minerals such as strontianite and smithsonite into the deposited layer. In order to develop a highly mature apatite coating, our method requires soaking of the pre-treated alloy in highly concentrated synthetic body fluid for only few hours. Surface characterizations were performed by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX) and Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS). Also, the deposited apatitic layers were analysed by powder diffraction X-ray analysis (XRD). 316L surface showed the growth of highly crystalline, low carbonated hydroxyapatite, after only 6h of the whole soaking process.
authors.affiliation: Physics Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, Egypt. a.adawy@science.ru.nl
authors.forename: Alaa
authors.initials: A
authors.lastname: Adawy
authors.forename: Wafa I
authors.initials: WI
authors.lastname: Abdel-Fattah
mesh_terms: D000497:Alloys / Q000494:pharmacology*; D040761:Biomimetic Materials / Q000494:pharmacology*; D032701:Biomimetics / Q000379:methods*; D001826:Body Fluids / Q000187:drug effects; D020099:Coated Materials, Biocompatible / Q000494:pharmacology*; D007501:Iron / Q000494:pharmacology; D008855:Microscopy, Electron, Scanning; D019736:Prostheses and Implants; D012996:Solutions; D013052:Spectrometry, X-Ray Emission; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D000497:Alloys; D020099:Coated Materials, Biocompatible; D012996:Solutions; C109374:SUS 316L; D007501:Iron
keywords: 10×SBF; 316L; DRIFTS; HA; Sr; Zn