title: A brief history of animal modeling.
abstract: Comparative medicine is founded on the concept that other animal species share physiological, behavioral, or other characteristics with humans. Over 2,400 years ago it was recognized that by studying animals, we could learn much about ourselves. This technique has now developed to the point that animal models are employed in virtually all fields of biomedical research including, but not limited to, basic biology, immunology and infectious disease, oncology, and behavior.
authors.affiliation: Mutant Mouse Regional Resource Center, Comparative Medicine Program, Department of Veterinary Pathobiology, University of Missouri, USA. franklinc@missouri.edu
authors.forename: Aaron C
authors.initials: AC
authors.lastname: Ericsson
authors.forename: Marcus J
authors.initials: MJ
authors.lastname: Crim
authors.forename: Craig L
authors.initials: CL
authors.lastname: Franklin
mesh_terms: D000818:Animals; D049668:History, 15th Century; D049669:History, 16th Century; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D049690:History, Ancient; D006801:Humans; D023421:Models, Animal; D057170:Translational Research, Biomedical / Q000266:history*