title: mTORC1 regulates glutamine metabolism.
abstract: mTORC1 stimulates glutamine metabolism by inducing glutamate dehydrogenase (GDH).
mesh_terms: D045744:Cell Line, Tumor; D049109:Cell Proliferation; D015972:Gene Expression Regulation, Neoplastic; D005969:Glutamate Dehydrogenase / Q000378:metabolism*; D005973:Glutamine / Q000378:metabolism*; D006801:Humans; D007656:Ketoglutaric Acids / Q000378:metabolism; D000076222:Mechanistic Target of Rapamycin Complex 1; D024101:Mitochondrial Proteins / Q000378:metabolism; D046912:Multiprotein Complexes / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D037761:Sirtuins / Q000378:metabolism; D058570:TOR Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism*
chemical_list: D007656:Ketoglutaric Acids; D024101:Mitochondrial Proteins; D046912:Multiprotein Complexes; D005973:Glutamine; D005969:Glutamate Dehydrogenase; D000076222:Mechanistic Target of Rapamycin Complex 1; D058570:TOR Serine-Threonine Kinases; C525357:SIRT4 protein, human; D037761:Sirtuins