title: Early-stage primary signet ring cell carcinoma of the colon.
abstract: Primary signet ring cell carcinoma of the colorectum detected at an early stage is very rare; most cases are detected at an advanced stage. Therefore, its prognosis is poorer than that of ordinary colorectal cancer. A 56-year-old Korean man was seen at this hospital for management of signet ring cell carcinoma of the colon. Colonoscopic examination revealed a IIa-like, ill-defined and flatly elevated 9-mm residual tumor in the cecum. Endoscopic mucosal resection was preformed. Pathological examination of the resected specimen revealed signet ring cell carcinoma that had invaded the lamina propria without venous or perineural invasion. Abdominal computed tomography (CT) and positron CT showed no evidence of primary lesions or distant metastasis. An additional laparoscopic right-hemicolectomy was performed; no residual tumor or lymph node metastasis was found. We report a case of primary signet ring cell carcinoma of the colon detected at an early stage and provide a review of the literature.
authors.affiliation: Department of Gastroenterology, Kosin University College of Medicine, Busan 602-702, South Korea.
authors.forename: Jae Hyun
authors.initials: JH
authors.lastname: Kim
authors.forename: Seun Ja
authors.initials: SJ
authors.lastname: Park
authors.forename: Moo In
authors.initials: MI
authors.lastname: Park
authors.forename: Won
authors.initials: W
authors.lastname: Moon
authors.forename: Sung Eun
authors.initials: SE
authors.lastname: Kim
mesh_terms: D018279:Carcinoma, Signet Ring Cell / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003082:Colectomy / Q000379:methods; D003110:Colonic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003113:Colonoscopy; D055088:Early Detection of Cancer; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D016896:Treatment Outcome
keywords: Colon carcinoma; Early stage; Endoscopic mucosal resection; Primary carcinoma; Signet ring cell carcinoma