title: Factors affecting bilirubin levels during first 48 hours of life in healthy infants.
abstract: OBJECTIVE
  To investigate the relationship of delivery type, maternal anesthesia, feeding modalities, and first feeding and meconium passage times with early bilirubin levels of healthy infants.
  
  
  METHODS
  Cord, 24 hours' and 48 hours' total bilirubin levels were measured in 388 study infants.
  
  
  RESULTS
  Infants born with cesarean section were fed later and more often had mixed feeding. First meconium passage was delayed with general anesthesia. Cord, 24 and 48 hours' bilirubin levels were not correlated with first feeding time, meconium passage time, mode of delivery, existence and type of anesthesia, and feeding modalities. Being in high intermediate risk zone at 72 hours of Bhutani's nomogram was only related to first feeding time and high cord bilirubin level. Late preterm infants were more frequently born with cesarean section and offered supplementary formula. Therefore, first meconium passage times and bilirubin levels were similar in the late preterm and term infants.
  
  
  CONCLUSIONS
  Type of delivery or anesthesia, late prematurity, feeding modalities, and first meconium passage time were not related to early bilirubin levels in healthy neonates, but delayed first feeding and high cord bilirubin levels were related to be in higher risk zone for later hyperbilirubinemia.
authors.affiliation: Division of Neonatology, Department of Pediatrics, Ege University Faculty of Medicine, Izmir, Turkey.
authors.forename: Betul
authors.initials: B
authors.lastname: Siyah Bilgin
authors.forename: Ozge
authors.initials: O
authors.lastname: Altun Koroglu
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yalaz
authors.forename: Semra
authors.initials: S
authors.lastname: Karaman
authors.forename: Nilgun
authors.initials: N
authors.lastname: Kultursay
mesh_terms: D000758:Anesthesia / Q000009:adverse effects; D001663:Bilirubin / Q000097:blood*; D001942:Breast Feeding; D002585:Cesarean Section; D005260:Female; D005312:Fetal Blood; D006801:Humans; D006932:Hyperbilirubinemia / Q000097:blood / Q000209:etiology / Q000473:pathology*; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases; D008470:Meconium / Q000378:metabolism; D011247:Pregnancy
chemical_list: D001663:Bilirubin