title: CT pulmonary angiography: an over-utilized imaging modality in hospitalized patients with suspected pulmonary embolism.
abstract: OBJECTIVE
  To determine if computed tomographic pulmonary angiography (CTPA) was overemployed in the evaluation of hospitalized patients with suspected acute pulmonary embolism (PE).
  
  
  METHODS
  Data were gathered retrospectively on hospitalized patients (n=185) who had CTPA for suspected PE between June and August 2009 at our institution.
  
  
  RESULTS
  CTPA was done in 185 hospitalized patients to diagnose acute PE based on clinical suspicion. Of these, 30 (16.2%) patients were tested positive for acute PE on CTPA. The Well's pretest probability for PE was low, moderate, and high in 77 (41.6%), 83 (44.9%), and 25 (13.5%) patients, respectively. Out of the 30 PE-positive patients, pretest probability was low in 2 (6.6%), moderate in 20 (66.7%), and high in 8 (26.6%) (p=0.003). Modified Well's criteria applied to all patients in our study revealed 113 (61%) with low and 72 (39%) with high clinical pretest probability. When modified Well's criteria was applied to 30 PE-positive patients, 10 (33.3%) and 20 (66.6%) were found to have low and high pretest probability, respectively (p=0.006). D-dimer assay was done in 30 (16.2%) of the inpatients with suspected PE and all of them were found to have elevated levels. A lower extremity duplex ultrasound confirmed deep venous thrombosis in 17 (9.1%) of the patients with suspected PE, at least 1 week prior to having CTPA.
  
  
  CONCLUSIONS
  Understanding the recommended guidelines, evidence-based literature, and current concepts in evaluation of patients with suspected acute PE will reduce unnecessary CTPA examinations.
authors.affiliation: Department of Internal Medicine, St Luke's Hospital, Bethlehem, PA, USA.
authors.forename: Penchala S
authors.initials: PS
authors.lastname: Mittadodla
authors.forename: Sunil
authors.initials: S
authors.lastname: Kumar
authors.forename: Erin
authors.initials: E
authors.lastname: Smith
authors.forename: Madhu
authors.initials: M
authors.lastname: Badireddy
authors.forename: Mohamed
authors.initials: M
authors.lastname: Turki
authors.forename: Gloria T
authors.initials: GT
authors.lastname: Fioravanti
keywords: CT pulmonary angiography; CTPA over utilization; PE; acute pulmonary embolism; diagnosis of PE