title: Diagnosis, prevention, and treatment of claudication.
abstract: Lower extremity chronic ischemia due to atherosclerosis represents the continuum of peripheral arterial disease, encompassing intermittent claudication, rest pain, and tissue loss. Traditionally, the indication for invasive intervention has been critical limb ischemia as a means to prevent amputation. This article highlights claudication and reviews its diagnosis, available treatment modalities, and preventative measures.
authors.affiliation: Section of Vascular Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
authors.forename: Jordan P
authors.initials: JP
authors.lastname: Knepper
authors.forename: Peter K
authors.initials: PK
authors.lastname: Henke
mesh_terms: D000368:Aged; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D002317:Cardiovascular Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D057510:Endovascular Procedures / Q000379:methods; D006801:Humans; D007383:Intermittent Claudication / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy; D008487:Medical History Taking; D008875:Middle Aged; D016540:Smoking Cessation; D014057:Tomography, X-Ray Computed
chemical_list: D002317:Cardiovascular Agents
keywords: Atherosclerosis; Claudication; Peripheral arterial disease