title: [Men with type 2 diabetes and erectile dysfunction are a particular risk group for LUTS - results of the Witten Diabetes Survey].
abstract: BACKGROUND
  According to our data on 4 071 patients with type 2 diabetes, 65.5% of the men and 70.4% of the women complain of lower urinary tract symptoms (LUTS). That is twice as much as the normal population for the same age group. The most common symptom was overactive bladder (OAB). In patients with a diabetes-related complication such as retinopathy or nephropathy, the incidence for LUTS was about 20% higher than that in patients without complications, whereas in men with diabetes mellitus type 2 and erectile dysfunction (ED) the incidence for LUTS was 31.9% higher than without ED. We wanted to compare the incidence of LUTS in patients with type 2 diabetes and ED against patients without ED as well as women with type 2 diabetes.
  
  
  RESULTS
  Men with ED had a statistically significant longer history of diabetes, a higher HbA1c and increased serum creatinine compared to men without ED (p value <0.0001). The length of diabetes history was not statistically relevant compared to women with type 2 diabetes. However the HbA1c and serum creatinine were higher than those of the women from the data bank (p value <0.0001). Diabetic men with ED complained more often of urinary incontinence, urge incontinence and made more often use of incontinence pads (p value <0.0001). As for pollakisuria and nocturia the difference was not significant. 42.3% of type 2 diabetic patients with ED were diagnosed with OAB by their urologist or GP. That was significantly more than type 2 diabetic patients without ED and type 2 diabetic women (see graph). The same was true of stress incontinence, overflow incontinence and non-classified incontinence with the exception of faecal incontinence. Patients with type 2 diabetes and ED had to take drugs more often than type 2 diabetic men without ED and women with diabetes.
  
  
  CONCLUSIONS
  Amongst patients with type 2 diabetes, ED increases the risk of developing lower urinary tract disorders. Moreover it is connected with a higher HbA1c and a higher risk for LUTS, especially for OAB. The regular use of incontinence pads in every fourth patient with type 2 diabetes and erectile dysfunction demonstrates a high number of under-treated patients. Patients with type 2 diabetes and especially patients with type 2 diabetes AND erectile dysfunction represent a risk group that needs special attention and a special management plan from urologists and GPs.
authors.affiliation: Urologische Abteilung, Evangelisches Krankenhaus Witten. awiedemann@diakonie-ruhr.de
authors.forename: A
authors.initials: A
authors.lastname: Wiedemann
authors.forename: N
authors.initials: N
authors.lastname: Meziane
authors.forename: J
authors.initials: J
authors.lastname: Hirsch
authors.forename: I
authors.initials: I
authors.lastname: Füsgen
mesh_terms: D000368:Aged; D015897:Comorbidity; D003404:Creatinine / Q000097:blood; D003430:Cross-Sectional Studies; D048909:Diabetes Complications / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D005260:Female; D005858:Germany; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D018783:Impotence, Vasculogenic / Q000453:epidemiology*; D015994:Incidence; D059411:Lower Urinary Tract Symptoms / Q000453:epidemiology* / Q000209:etiology*; D008297:Male; D012307:Risk Factors; D012737:Sex Factors; D053201:Urinary Bladder, Overactive / Q000453:epidemiology; D014549:Urinary Incontinence / Q000453:epidemiology
chemical_list: D003404:Creatinine; D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human