title: RAS mutations in thyroid cancer.
abstract: In recent years, our understanding of the genetic alterations underlying thyroid oncogenesis has greatly expanded. The use of molecular markers, including RAS, in the management of thyroid carcinoma is also increasing. This review summarizes the current literature surrounding RAS and discusses its potential as a diagnostic and prognostic indicator in the management of thyroid cancer.
authors.affiliation: Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.
authors.forename: Gina M
authors.initials: GM
authors.lastname: Howell
authors.forename: Steven P
authors.initials: SP
authors.lastname: Hodak
authors.forename: Linwah
authors.initials: L
authors.lastname: Yip
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics*; D006801:Humans; D009154:Mutation; D011379:Prognosis; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D018631:ras Proteins / Q000235:genetics* / Q000627:therapeutic use
chemical_list: D014408:Biomarkers, Tumor; D018631:ras Proteins
keywords: Molecular markers; RAS; Thyroid cancer; Thyroid nodules