title: Anti-inflammatory and antioxidative effects of a methanol extract from bulbs of Scilla scilloides.
abstract: The extract from bulbs of Scilla scilloides exhibited inhibitory effects in lipoxygenase and hyaluronidase assays and various oxidation models in vitro. Incubating the cells in the presence of this extract ameliorated t-butyl hydroperoxide-induced cytotoxicity from 27% to 57% in a macrophage model. The results may indicate the potential role of S. scilloides for its anti-inflammatory and antioxidative effects.
authors.affiliation: Department of Bioscience, School of Agriculture, Tokai University, Kyoto 606-8502, Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Yasuda
authors.forename: Youichirou
authors.initials: Y
authors.lastname: Nishida
authors.forename: Kensuke
authors.initials: K
authors.lastname: Wada
authors.forename: Daisuke
authors.initials: D
authors.lastname: Akiyama
authors.forename: Daiki
authors.initials: D
authors.lastname: Toyohisa
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Tanaka
authors.forename: Keiji
authors.initials: K
authors.lastname: Igoshi
authors.forename: Masateru
authors.initials: M
authors.lastname: Ono
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000302:isolation & purification / Q000494:pharmacology*; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D002460:Cell Line; D008264:Macrophages / Q000378:metabolism; D000432:Methanol / Q000737:chemistry*; D051379:Mice; D018384:Oxidative Stress / Q000187:drug effects; D018547:Plant Stems / Q000737:chemistry*; D031445:Scilla / Q000737:chemistry*
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D000432:Methanol