title: CD4+ T cell count, HIV-1 viral loads and demographic variables of newly identified patients with HIV infection in Wuhan, China.
abstract: In China, the rate of human immunodeficiency virus (HIV) testing is increasing among men who have sex with men. The purpose of the present study was to describe HIV-related biomarkers and selected demographic variables of persons with newly diagnosed HIV/AIDS, among men who have sex with men in particular, in Wuhan China. Demographic indicators, and CD4+ T cell counts and HIV-1 viral load were collected from individuals newly identified as HIV-1 antibody positive during 2011. Of 176 enrolled patients, 132 (75.0%) were men who have sex with men. This group was significantly younger and had higher CD4+ T cell counts than patients who were likely infected through heterosexual contact. Most men who have sex with men (56.6%) were discovered by initiative investigation. Among heterosexual patients CD4+ T cell counts and HIV-1 viral load were significantly correlated; among the group of men who have sex with men, no such association was found.
authors.affiliation: Wuhan Centers for Disease Prevention and Control, Wuhan, China.
authors.forename: Man-Qing
authors.initials: MQ
authors.lastname: Liu
authors.forename: Li
authors.initials: L
authors.lastname: Tang
authors.forename: Wen-Hua
authors.initials: WH
authors.lastname: Kong
authors.forename: Ze-Rong
authors.initials: ZR
authors.lastname: Zhu
authors.forename: Jin-Song
authors.initials: JS
authors.lastname: Peng
authors.forename: Xia
authors.initials: X
authors.lastname: Wang
authors.forename: Zhong-Zhao
authors.initials: ZZ
authors.lastname: Yao
authors.forename: Robert
authors.initials: R
authors.lastname: Schilling
authors.forename: Wang
authors.initials: W
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D018791:CD4 Lymphocyte Count; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D002681:China / Q000453:epidemiology; D003710:Demography; D005260:Female; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012725:Sexual Behavior; D019562:Viral Load; D055815:Young Adult
chemical_list: D015483:HIV Antibodies
keywords: CD4+ T cell counts; HIV-1 viral load; Wuhan; heterosexual; men who have sex with men