title: An evaluation of neuropeptide Y status in subacute sclerosing panencephalitis patients.
abstract: OBJECTIVE
  This study aimed to evaluate the neuropeptide Y values of patients with subacute sclerosing panencephalitis.
  
  
  METHODS
  The study comprised 38 patients diagnosed with subacute sclerosing panencephalitis at our clinic, who were being routinely followed-up, together with a control group of 36. Using the Risk and Haddad classification for clinical staging, 16 patients were determined as Stage II and 22 patients as Stage III. Neuropeptide Y values were measured by Enzyme Immunoassay methods.
  
  
  RESULTS
  The neuropeptide Y values of the all patients with subacute sclerosing panencephalitis were found to be significantly high compared to the control group (p<0.01). The neuropeptide Y values of the Stage III group were found to be significantly high compared to the Stage II and control groups (p<0.05). The neuropeptide Y values of the Stage II group were not determined to be significant compared to the control group (p≤0.05).
  
  
  CONCLUSIONS
  Neuropeptide Y can be considered a useful parameter to confirm diagnosis at advanced stages and to establish differences between stages in patients with subacute sclerosing panencephalitis.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Harran University, Sanliurfa, Turkey. drabuhandan@mynet.com
authors.forename: M
authors.initials: M
authors.lastname: Abuhandan
authors.forename: M
authors.initials: M
authors.lastname: Calik
authors.forename: V
authors.initials: V
authors.lastname: Almaz
authors.forename: A
authors.initials: A
authors.lastname: Taskın
authors.forename: A
authors.initials: A
authors.lastname: Cakmak
authors.forename: S
authors.initials: S
authors.lastname: Selek
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009478:Neuropeptide Y / Q000097:blood*; D012720:Severity of Illness Index; D013344:Subacute Sclerosing Panencephalitis / Q000097:blood*
chemical_list: D009478:Neuropeptide Y