title: [Dependence of a functionally-metabolic state of phagocytes and a complement activity from the immune deficiency degree in the patients with HIV-infection].
abstract: Some indices of nonspeciphic immunity were analyzed in 60 HIV-infected patients with various content of CD4-lymphocytes. In a HIV-infected persons, not depending on the CD4-lymphocytes content, the raising of the circulating immune complexes level was revealed. When the CD4-lymphocytes content is less than 200 cells in 1 microl the complement (CH50) activity is raising, bactericidal activity of phagocytes (in accordance with the HCT-test data) is lowering. These changes cause no effective intracellular elimination, enhancement of persistence of causative agents in phagocytes and their further dissemination in organism of the patients.
authors.forename: D H
authors.initials: DH
authors.lastname: Zhyvytsia
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000097:blood / Q000453:epidemiology / Q000276:immunology; D000328:Adult; D000936:Antigen-Antibody Complex / Q000097:blood*; D018791:CD4 Lymphocyte Count; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D016022:Case-Control Studies; D015941:Complement Hemolytic Activity Assay; D005260:Female; D015658:HIV Infections / Q000097:blood / Q000453:epidemiology / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010586:Phagocytes / Q000276:immunology* / Q000378:metabolism*; D010587:Phagocytosis / Q000276:immunology; D055815:Young Adult
chemical_list: D000936:Antigen-Antibody Complex