title: A red fluorescent turn-on probe for hydrogen sulfide and its application in living cells.
abstract: A novel selective fluorescent chemosensor has been synthesized with a phenanthrene-fused dipyrromethene structure. Selective binding of Cu(2+) by results in a complex that displays high selectivity and sensitivity for H2S. The signal transduction occurs via reversible formation-separation of the complex and CuS. Its potential utility for biological applications was confirmed by fluorescence imaging of H2S in live cells.
authors.affiliation: State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210093, P. R. China.
authors.forename: Xingyu
authors.initials: X
authors.lastname: Qu
authors.forename: Cuijuan
authors.initials: C
authors.lastname: Li
authors.forename: Huachao
authors.initials: H
authors.lastname: Chen
authors.forename: John
authors.initials: J
authors.lastname: Mack
authors.forename: Zijian
authors.initials: Z
authors.lastname: Guo
authors.forename: Zhen
authors.initials: Z
authors.lastname: Shen
mesh_terms: D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D006862:Hydrogen Sulfide / Q000032:analysis*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D011789:Quantum Theory
chemical_list: D005456:Fluorescent Dyes; D009942:Organometallic Compounds; D006862:Hydrogen Sulfide