title: Modeling of cerebral aneurysm using equivalent electrical circuit (Lumped Model).
abstract: The circle of Willis (CoW) is a key asset in brain performance as it supports adequate blood supply to the brain. The lumped method (electrical equivalent circuits) is a useful model to simulate the process of the human cardiovascular system. In this study, the whole cardiovascular system is modeled, using an equivalent electrical circuit to investigate an aneurysm in an artery. The cerebrovascular system consists of 29 compartments, which includes the CoW. Each vessel is modeled by a resistor, a capacitor and an inductor. Using MATLAB Simulink, the left and right ventricles are modeled by controlled voltage sources and diodes. The effects of the left internal carotid artery aneurysm (Fusiform) on the pressure of the efferent arteries in the circle of Willis are studied. The modeling results are entirely in agreement with the available clinical observations. The results of the present study may have clinical implications for modeling different cardiovascular diseases, such as arterial stiffness and atherosclerosis.
authors.affiliation: 1Department of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Abdi
authors.forename: A
authors.initials: A
authors.lastname: Karimi
authors.forename: M
authors.initials: M
authors.lastname: Navidbakhsh
authors.forename: K
authors.initials: K
authors.lastname: Hassani
authors.forename: S
authors.initials: S
authors.lastname: Faghihi
mesh_terms: D002941:Circle of Willis / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D002532:Intracranial Aneurysm / Q000473:pathology* / Q000503:physiopathology*; D008955:Models, Cardiovascular
keywords: aneurysm; cerebrovascular; circle of Willis (CoW); left internal carotid artery; lumped method