title: Synthesis and antioxidant activity of a novel class of fluorescein-based β-C-glycosides.
abstract: A series of fluorescein-based β-C-glycosyl ketones were synthesized through aldol condensation of β-C-glycosyl ketones with fluorescein monoaldehyde under ambient reaction conditions in good yields. Formation of the expected product has been confirmed through different spectral techniques. Fluorescein-based β-C-glycosides show moderate anti-oxidant activities with maximum inhibitory activity of 60%.
authors.affiliation: Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai, India.
authors.forename: Mani
authors.initials: M
authors.lastname: Rajasekar
authors.forename: Thangamuthu Mohan
authors.initials: TM
authors.lastname: Das
mesh_terms: D000975:Antioxidants / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000037:antagonists & inhibitors; D019793:Fluorescein / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000037:antagonists & inhibitors; D006027:Glycosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D015394:Molecular Structure; D010851:Picrates / Q000037:antagonists & inhibitors
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D006027:Glycosides; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl; D019793:Fluorescein
keywords: Aldol condensation; Antioxidant activity; Fluorescein derivatives; β-C-glycosides