title: Pharmacological treatment of acute heart failure: current treatment and new targets.
abstract: Acute heart failure (AHF) is defined as the rapid onset of, or changes in, the symptoms and signs of heart failure (HF). It is a life-threatening situation in which diagnosis and initiation of therapy are crucial. The treatment aims are to stabilize the patient, improve clinical symptoms, and increase long-term survival rates. Few treatments have been investigated in clinical trials. This review summarizes the principles of pharmacologic treatment, the underlying clinical trials, and new pharmacologic targets.
authors.affiliation: Universitätsklinikum des Saarlandes, Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Homburg/Saar, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Pöss
authors.forename: A
authors.initials: A
authors.lastname: Link
authors.forename: M
authors.initials: M
authors.lastname: Böhm
mesh_terms: D000208:Acute Disease; D000701:Analgesics, Opioid / Q000627:therapeutic use; D002316:Cardiotonic Agents / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D015507:Drugs, Investigational / Q000627:therapeutic use*; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D058990:Molecular Targeted Therapy / Q000639:trends*; D018847:Opioid Peptides; D010100:Oxygen / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D014662:Vasoconstrictor Agents / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000701:Analgesics, Opioid; D002316:Cardiotonic Agents; D004232:Diuretics; D015507:Drugs, Investigational; D018847:Opioid Peptides; D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents; D010100:Oxygen