title: [Research progress of mesenchymal stem cells in burn wound repair].
abstract: OBJECTIVE
  To review the research progress of mesenchymal stem cells (MSCs) in burn wound repair.
  
  
  METHODS
  The recent literature about MSCs involved in burn wound repair and mechanism was extensively reviewed and analyzed.
  
  
  RESULTS
  MSCs have the capacity of self-renew, rapid proliferation, differentiation and paracrine, and promote burn wound repair through differentiating into a series of skin wound cells and regulating wound microenvironment.
  
  
  CONCLUSIONS
  MSCs have great potentials in the burn field. However, the cell survival and outcome are also facing challenges from poor microenvironment of the burn wound.
authors.affiliation: Department of Burn & Plastic Surgery, the First Affiliated Hospital of Chinese PLA General Hospital, Beijing, 100037, PR China.
authors.forename: Yusen
authors.initials: Y
authors.lastname: Huo
authors.forename: Hongjie
authors.initials: H
authors.lastname: Duan
authors.forename: Lingying
authors.initials: L
authors.lastname: Liu
authors.forename: Quan
authors.initials: Q
authors.lastname: Hu
authors.forename: Jiake
authors.initials: J
authors.lastname: Chai
mesh_terms: D000818:Animals; D002056:Burns / Q000473:pathology / Q000628:therapy*; D002454:Cell Differentiation; D002465:Cell Movement; D049109:Cell Proliferation; D002478:Cells, Cultured; D016207:Cytokines / Q000378:metabolism; D005347:Fibroblasts / Q000166:cytology / Q000502:physiology; D006801:Humans; D008214:Lymphocytes / Q000276:immunology / Q000378:metabolism; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000276:immunology / Q000502:physiology; D018919:Neovascularization, Physiologic / Q000502:physiology*; D012867:Skin / Q000293:injuries* / Q000378:metabolism / Q000473:pathology; D023822:Tissue Engineering; D014945:Wound Healing / Q000502:physiology*
chemical_list: D016207:Cytokines