title: Modeling the shape of cylindrically focused transducers in three-dimensional optoacoustic tomography.
abstract: Cross sectional tomographic systems based on cylindrically focused transducers are widely used in optoacoustic (photoacoustic) imaging due to important advantages they provide such as high-cross sectional resolution, real-time imaging capacity, and high-throughput performance. Tomographic images in such systems are commonly obtained by means of two-dimensional (2-D) reconstruction procedures assuming point-like detectors, and volumetric (whole-body) imaging is performed by superimposing the cross sectional images for different positions along the scanning direction. Such reconstruction strategy generally leads to in-plane and out-of-plane artifacts as well as significant quantification errors. Herein, we introduce two equivalent full three-dimensional (3-D) models capable of accounting for the shape of cylindrically focused transducers. The performance of these models in 3-D reconstructions considering several scanning positions is analyzed in this work. Improvements of the results rendered with the introduced reconstruction procedure as compared with the 2-D-based approach are described and discussed for simulations and experiments with phantoms and biological tissues.
authors.affiliation: Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany. daniel.queiros@helmholtz-muenchen.de
authors.forename: Daniel
authors.initials: D
authors.lastname: Queirós
authors.forename: Xosé Luís
authors.initials: XL
authors.lastname: Déan-Ben
authors.forename: Andreas
authors.initials: A
authors.lastname: Buehler
authors.forename: Daniel
authors.initials: D
authors.lastname: Razansky
authors.forename: Amir
authors.initials: A
authors.lastname: Rosenthal
authors.forename: Vasilis
authors.initials: V
authors.lastname: Ntziachristos
mesh_terms: D000818:Animals; D003198:Computer Simulation; D005583:Fourier Analysis; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D051379:Mice; D019047:Phantoms, Imaging; D061088:Photoacoustic Techniques / Q000295:instrumentation / Q000379:methods*; D013154:Spleen / Q000033:anatomy & histology; D041622:Tomography, Optical / Q000295:instrumentation / Q000379:methods*; D014159:Transducers