title: [A case of long remission for about 5 years as an outpatient with second-line chemotherapy of weekly PTX after palliative distal gastrectomy for pStage IV advanced gastric cancer].
abstract: A 59-year-old man underwent palliative distal gastrectomy for Stage IV advanced gastric cancer with cytological and histopathological peritoneal dissemination. After surgery, he began to receive chemotherapy by S-1 oral administration as an outpatient. About one year and 9 months after surgery, cartinomatous peritonitis grew, and severe obstruction of gastrojejunostomy and dilatation of residual stomach were detected by CT tomography. Then, second-line chemotherapy by weekly paclitaxel(PTX)was started. After one course of weekly PTX was completed, he was feeling better gradually with obvious improvement of carcinomatous peritonitis, which was revealed by sequential CT tomography examinations. Weekly PTX chemotherapy has been continued successfully for 43 courses, and he remains alive today with a good QOL, about 5 years after surgery. He is an outpatient with only a grade 2 or less complication of peripheral neuropathy.
authors.affiliation: Dept. of Surgery, Hyogo Prefectural Tsukaguchi Hospital.
authors.forename: Takashi
authors.initials: T
authors.lastname: Imamura
authors.forename: Satoru
authors.initials: S
authors.lastname: Chujo
authors.forename: Kumiko
authors.initials: K
authors.lastname: Suzuki
authors.forename: Hideaki
authors.initials: H
authors.lastname: Iwama
authors.forename: Shohei
authors.initials: S
authors.lastname: Kondo
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Suwa
authors.forename: Jun
authors.initials: J
authors.lastname: Tamura
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Katayama
authors.forename: Gakuji
authors.initials: G
authors.lastname: Ohshio
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010045:Outpatients; D017239:Paclitaxel / Q000627:therapeutic use*; D010166:Palliative Care; D011788:Quality of Life; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel