title: Protein structure in context: the molecular landscape of angiogenesis.
abstract: A team of students, educators, and researchers has developed new materials to teach cell signaling within its cellular context. Two nontraditional modalities are employed: physical models, to explore the atomic details of several of the proteins in the angiogenesis signaling cascade, and illustrations of the proteins in their cellular environment, to give an intuitive understanding of the cellular context of the pathway. The experiences of the team underscore the use of these types of materials as an effective mode for fostering students' understanding of the molecular world and the scientific method used to define it.
authors.affiliation: Department of Pharmaceutical Sciences, Concordia University Wisconsin, Mequon, WI 53097, USA
authors.forename: Elise A
authors.initials: EA
authors.lastname: Span
authors.forename: David S
authors.initials: DS
authors.lastname: Goodsell
authors.forename: Ramani
authors.initials: R
authors.lastname: Ramchandran
authors.forename: Margaret A
authors.initials: MA
authors.lastname: Franzen
authors.forename: Tim
authors.initials: T
authors.lastname: Herman
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Sem
mesh_terms: D043925:Angiogenesis Inducing Agents / Q000737:chemistry*; D003479:Curriculum / Q000592:standards*; D006801:Humans; D008962:Models, Theoretical; D008967:Molecular Biology / Q000193:education*; D015394:Molecular Structure; D011506:Proteins / Q000737:chemistry*; D015398:Signal Transduction; D013334:Students
chemical_list: D043925:Angiogenesis Inducing Agents; D011506:Proteins
keywords: VEGF signaling; angiogenesis; protein structure; visual learning