title: Cyclohexyl iodide promoted approach for coumarin analog synthesis using small scaffold.
abstract: New chemical approaches were adopted for the synthesis of biologically important coumarins utilizing cyclohexane-1,3-dione derivatives as novel scaffold which were prepared from acetone and ethyl acrylate following our previous report. The stepwise strategies of aromatization, dehydrogenation, and demethylative cyclization were followed for coumarins synthesis from cyclohexane-1,3-dione derivatives. This work reports the first time cyclohexyl iodide was used for the demethylative cyclization reaction of [Formula: see text]-diaryl acrylates for 4-arylcoumarins synthesis.
authors.affiliation: Natural Plant Products Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, 176061, HP, India.
authors.forename: Dharminder
authors.initials: D
authors.lastname: Sharma
authors.forename: C B
authors.initials: CB
authors.lastname: Reddy
authors.forename: Arun K
authors.initials: AK
authors.lastname: Shil
authors.forename: Rashi Prakash
authors.initials: RP
authors.lastname: Saroach
authors.forename: Pralay
authors.initials: P
authors.lastname: Das
mesh_terms: D003374:Coumarins / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D007454:Iodides / Q000737:chemistry*
chemical_list: D003374:Coumarins; D007454:Iodides; C030123:coumarin