title: Fatal neurological side-effects with necrosis of spinal cord following nelarabine treatment in a child with relapsed T-cell acute lymphoblastic leukemia.
authors.affiliation: Clinic of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
authors.forename: Bernd
authors.initials: B
authors.lastname: Hartz
authors.forename: Ulrike
authors.initials: U
authors.lastname: Löbel
authors.forename: Christian
authors.initials: C
authors.lastname: Hagel
authors.forename: Gabriele
authors.initials: G
authors.lastname: Escherich
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects*; D001087:Arabinonucleosides / Q000008:administration & dosage / Q000009:adverse effects*; D002531:Cerebellum / Q000187:drug effects / Q000473:pathology; D002648:Child; D003520:Cyclophosphamide / Q000008:administration & dosage; D003561:Cytarabine / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D017809:Fatal Outcome; D020275:Guillain-Barre Syndrome / Q000139:chemically induced*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008526:Medulla Oblongata / Q000187:drug effects / Q000473:pathology; D008727:Methotrexate / Q000008:administration & dosage; D009336:Necrosis; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy*; D011239:Prednisolone / Q000008:administration & dosage; D012008:Recurrence; D012640:Seizures / Q000139:chemically induced*; D013116:Spinal Cord / Q000187:drug effects / Q000473:pathology*
chemical_list: D000964:Antimetabolites, Antineoplastic; D001087:Arabinonucleosides; D003561:Cytarabine; C104457:nelarabine; D005047:Etoposide; D003520:Cyclophosphamide; D011239:Prednisolone; D008727:Methotrexate