title: Regression of severe Behcet's eye disease with infliximab therapy; .first two cases treated in Pakistan.
abstract: We present two cases of Behcet's Disease with severe eye problems along with oral and genital ulcerations. Both cases, initially were treated with steroids and oral immunosuppressive agents, but did not show a response and ocular disease became worse. Both the cases were kept on Infliximab therapy. an immediate positive response with improvement in vision and symptoms was seen. After initial infusions the ocular damage in both the cases stopped.
authors.affiliation: Department of Medicine, Aga Khan University Hospital, Karachi. saliha.ishaq@aku.edu
authors.forename: Saliha
authors.initials: S
authors.lastname: Ishaq
authors.forename: Anum
authors.initials: A
authors.lastname: Saeed
authors.forename: Majid
authors.initials: M
authors.lastname: Jawad
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D001528:Behcet Syndrome / Q000188:drug therapy*; D005128:Eye Diseases / Q000188:drug therapy*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D000069285:Infliximab; D008297:Male
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000911:Antibodies, Monoclonal; D005938:Glucocorticoids; D000069285:Infliximab