title: Synthesis of spiro[indoline-3,1'-quinolizines] and spiro[indoline-3, 4'-pyrido[1,2-a]quinolines] via three-component reactions of azaarenes, acetylenedicarboxylate, and 3-methyleneoxindoles.
abstract: The three-component reactions of substituted pyridines, dimethyl acetylenedicarboxylates, and 3-phenacylideneoxindoles afforded spiro[indoline-3,1'quinolizines] in high yields and with high diastereoselectivity. The Diels-Alder reactions of spiro[indoline-3,1' quinolizines] with maleic anhydride and N- phenyl maleimides successfully resulted in polyfunctionalized isoquinolinuclidine derivatives. The similar three-component reactions with quinoline resulted in the novel spiro[indoline-3,4' -pyrido[1,2-a]quinolines] in moderate to good yields.
authors.affiliation: College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou,  225002, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Sun
authors.forename: Hui
authors.initials: H
authors.lastname: Gong
authors.forename: Yan
authors.initials: Y
authors.lastname: Sun
authors.forename: Chao-Guo
authors.initials: CG
authors.lastname: Yan
mesh_terms: D020650:Combinatorial Chemistry Techniques; D061565:Cycloaddition Reaction; D015394:Molecular Structure; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D013141:Spiro Compounds