title: Emerging concepts in the management of acute retinal necrosis.
abstract: Acute retinal necrosis (ARN), also known as Kirisawa-type uveitis, is an uncommon condition caused by infection of the retina by one of the herpes family of viruses, most typically varicella zoster virus or herpes simplex virus and less commonly cytomegalovirus. Clinical diagnosis can be challenging and is often aided by PCR-based analysis of ocular fluids. Treatment typically involves extended use of one or more antiviral agents. Long term retinal detachment risk is high. We review the literature on ARN and present an approach to the diagnosis and management of this serious condition.
authors.affiliation: Austin Retina Associates, Austin, Texas, USA.
authors.forename: Robert William
authors.initials: RW
authors.lastname: Wong
authors.forename: J Michael
authors.initials: JM
authors.lastname: Jumper
authors.forename: H Richard
authors.initials: HR
authors.lastname: McDonald
authors.forename: Robert N
authors.initials: RN
authors.lastname: Johnson
authors.forename: Arthur
authors.initials: A
authors.lastname: Fu
authors.forename: Brandon J
authors.initials: BJ
authors.lastname: Lujan
authors.forename: Emmett T
authors.initials: ET
authors.lastname: Cunningham
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D003587:Cytomegalovirus; D014645:Herpesvirus 3, Human; D006801:Humans; D015882:Retinal Necrosis Syndrome, Acute / Q000628:therapy*
chemical_list: D000998:Antiviral Agents
keywords: Infection; Inflammation