title: [Contamination of surgical materials by exfoliated cancer cells during gastric carcinoma operation].
abstract: OBJECTIVE
  To explore the exfoliated cancer cell contamination in different surgical materials during the malignant gastrectomy.
  
  
  METHODS
  Ninety gastric cancer patients undergoing gastrectomy were prospectively enrolled in this study. The operation materials of these 90 gastrectomy were divided into 5 groups: surgical instruments (A), gloves for surgeons (B), gloves and gauzes of scrub nurse (C), gauzes for hemostasis (D), anastomosis instrument (E). The rinse fluid of materials was cultured to verify positive cancer cells. Associations among different pathological stages, differentiations, materials and positive cancer cells rates were examined.
  
  
  RESULTS
  Stage II and III patients had higher positive rates of exfoliated cancer cell contamination than stage I patients [26.5 (9/34) and 47.5% (21/46) vs. 10.0% (1/10),P=0.046]. Low differentiated adenocarcinoma group had higher positive rate than moderately and well differentiated adenocarcinoma groups [44.8% (26/58) vs. 16.7% (4/24) and 12.5% (1/8), P=0.020]. Positive cancer cell rates of 5 kinds of materials were as follows: 12.2% (11/90) in A group, 6.7% (6/90) in B group, 22.2% (20/90) in C group, 15.6% (14/90) in D group and 3.3% (3/90) in E group, and the differences were significant (P<0.01).
  
  
  CONCLUSIONS
  Different operation materials have different risks to be contaminated by cancer cells, which is associated with the contact frequency, cancer staging and pathological classification.
authors.affiliation: Department of Surgery, Zhejiang Provincial People's Hospital, Hangzhou, China. yxf4800@163.com
authors.forename: Xiao-fen
authors.initials: XF
authors.lastname: Yu
authors.forename: Zai-yuan
authors.initials: ZY
authors.lastname: Ye
authors.forename: Qin-fang
authors.initials: QF
authors.lastname: Zhang
authors.forename: Xian-qin
authors.initials: XQ
authors.lastname: Hu
mesh_terms: D000328:Adult; D000368:Aged; D004866:Equipment Contamination; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009366:Neoplasm Seeding; D011446:Prospective Studies; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery*; D013523:Surgical Equipment