title: One-pot synthesis of dihydropyrano [2,3-c]chromenes via a three-component reaction in aqueous media.
abstract: An efficient protocol for the synthesis of dihydropyrano [2,3-c] chromenes derivatives by one-pot threecomponent reaction of aromatic aldehydes, malononitrile or methyl cyanoacetate, and 4-hydroxy coumarin has been developed using catalytic amount (10%) of three different catalysts piperidine, triethyl amine, and natrium carbonate in aqueous media. The present protocol has significant features such as easy set-up and work-up, environmentally benign, high yields, short reaction times.
authors.affiliation: Peptide Chemistry Research Center, K. N. Toosi University of Technology, P. O. Box 15875-4416, Tehran, Iran. balalaie@kntu.ac.ir.
authors.forename: Saeed
authors.initials: S
authors.lastname: Balalaie
authors.forename: Ahmad
authors.initials: A
authors.lastname: Khazaie
authors.forename: Morteza
authors.initials: M
authors.lastname: Ashouriha
mesh_terms: D001578:Benzopyrans / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D014867:Water / Q000737:chemistry*
chemical_list: D001578:Benzopyrans; D014867:Water