title: [Arthropathia ochronotica: a rare cause of early joint degeneration].
abstract: METHODS
  A 70-year-old deaf-mute women suffered from progressive chronic pain of the right hip joint caused by destructive osteoarthritis of the hip.
  
  
  METHODS
  In addition to painfully restricted range of motion of the right hip joint the clinical examination showed a bluish-black pigmentation of the ear-cartilage and the sclera.
  
  
  METHODS
  A total endoprosthetic replacement of the right hip joint was performed. During surgery, blackening of the hip joint capsule and cartilage was found. Histological, the diagnosis of an ochronosis was confirmed. Discoloration after exposure of urine to air supported the diagnosis. Based on extensive internal medical examination relevant cardiac changes were excluded.
  
  
  CONCLUSIONS
  Ochronosis (arthropathia ochronotica) is a rare entity which can be identified by a visual diagnosis. Early diagnosis can provide crucial information for the prognosis. Additionally, an interdisciplinary treatment concept should be established because of the early onset of degenerative changes at the skeletal system and pathological changes at internal organs. With suspicion on an ochronosis extended internal examinations are recommended in order to avoid complications.
authors.affiliation: Abteilung Orthopädie, Universitätsklinikum Halle/Saale, Germany. sven.freche@uk-halle.de
authors.forename: S
authors.initials: S
authors.lastname: Freche
authors.forename: E
authors.initials: E
authors.lastname: Esmer
authors.forename: K-S
authors.initials: KS
authors.lastname: Delank
authors.forename: H
authors.initials: H
authors.lastname: Bürger
authors.forename: F
authors.initials: F
authors.lastname: Juch
authors.forename: D
authors.initials: D
authors.lastname: Wohlrab
mesh_terms: D000368:Aged; D018771:Arthralgia / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009794:Ochronosis / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D015207:Osteoarthritis, Hip / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D035583:Rare Diseases / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D016896:Treatment Outcome