title: Depression and health related quality of life in breast cancer patients.
abstract: OBJECTIVE
  To investigate the prevalence of depression in women with breast cancer and relate it to their health-related quality of life.
  
  
  METHODS
  The cross-sectional study was conducted at the Imam Khomeini Hospital in Iran between January and December 2009, and comprised 60 women with breast cancer with a mean age of 43.8 +/- 47.12 years. In order to assess the health-related quality of life, the study used the parameters of the Iranian version of the Functional Assessment of Cancer Therapy for Breast Cancer. To identify expressive symptoms, the Beck Depression Inventory was used. General linear model regression and SPSS 14 were used to analyse the data.
  
  
  RESULTS
  Significant differences in the prevalence of depression between treatment types was found. The presence of depression was significantly correlated with poorer overall health-related quality of life and the four subscales of the protocol. The patients reported statistically significant effects of depression in the overall category (p= 0.001). Participants with depression were more likely to have a poorer overall health-related quality of life, the exception being the social/family well-being subscale.
  
  
  CONCLUSIONS
  Depression affects health-related quality of life in breast cancer patients. Although further studies are necessary to confirm our findings, but our results emphasise the necessity for better mental health strategies for such patients.
authors.affiliation: Clinical Psychology Department, Panjab University, India. didehdar@gmail.com
authors.forename: Maryam Didehdar
authors.initials: MD
authors.lastname: Ardebil
authors.forename: Zinnatossadat
authors.initials: Z
authors.lastname: Bouzari
authors.forename: Mohsen Hagh
authors.initials: MH
authors.lastname: Shenas
authors.forename: Masoud
authors.initials: M
authors.lastname: Keighobadi
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000150:complications / Q000175:diagnosis / Q000523:psychology*; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006304:Health Status; D006801:Humans; D007492:Iran; D008603:Mental Health; D008875:Middle Aged; D015995:Prevalence; D011788:Quality of Life; D055815:Young Adult