title: Pulmonary veno-occlusive disease in a female gardener.
abstract: Pulmonary veno-occlusive disease (PVOD) is a subgroup of pulmonary arterial hypertension with a poor prognosis. The diagnosis is usually delayed and treatment options other than lung transplantation are unfortunately limited. We report the case of 51-year-old female gardener diagnosed with PVOD by open lung biopsy before her death. Although there are many reported cases of hepatic veno-occlusive disease due to toxic agents present in nature, such as pyrrolizidine alkaloid exposure, to date this has not been linked to PVOD.
authors.affiliation: Servicio de Neumología, Hospital General Universitario Gregorio Marañón, IiSGM, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Paula
authors.initials: P
authors.lastname: Rodríguez Rodríguez
authors.affiliation: Servicio de Neumología, Hospital General Universitario Gregorio Marañón, IiSGM, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Fernando
authors.initials: F
authors.lastname: Pedraza Serrano
authors.affiliation: Servicio de Neumología, Hospital General Universitario Gregorio Marañón, IiSGM, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Liliana Patricia
authors.initials: LP
authors.lastname: Morán Caicedo
authors.affiliation: Servicio de Neumología, Hospital General Universitario Gregorio Marañón, IiSGM, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Maria Carmen
authors.initials: MC
authors.lastname: Rodríguez de Guzmán
authors.affiliation: Departamento de Anatomía Patológica, Hospital General Universitario Gregorio Marañón, Madrid, España.
authors.forename: María
authors.initials: M
authors.lastname: Cebollero Presmanes
authors.affiliation: Servicio de Neumología, Hospital General Universitario Gregorio Marañón, IiSGM, Universidad Complutense de Madrid, Madrid, España. Electronic address: jmiguel.hgugm@salud.madrid.org.
authors.forename: Javier
authors.initials: J
authors.lastname: de Miguel Díez
mesh_terms: D001706:Biopsy; D057210:Delayed Diagnosis; D018450:Disease Progression; D004417:Dyspnea / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D051639:Gardening; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology; D008875:Middle Aged; D016273:Occupational Exposure; D010944:Plants / Q000737:chemistry; D011668:Pulmonary Veno-Occlusive Disease / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D011763:Pyrrolizidine Alkaloids / Q000633:toxicity*; D014057:Tomography, X-Ray Computed
chemical_list: D011763:Pyrrolizidine Alkaloids
keywords: Biopsia pulmonar abierta; Edema pulmonar; Enfermedad pulmonar venooclusiva; Hipertensión arterial pulmonar; Open lung biopsy; Pulmonary arterial hypertension; Pulmonary edema; Pulmonary veno-occlusive disease