title: Fenofibrate-induced rhabdomyolysis in a patient with stage 4 chronic renal failure due to diabetes mellitus.
abstract: Rhabdomyolysis is defined as a pathological condition of skeletal muscle cell damage leading to the release of toxic intracellular components into the circulation. Several factors may lead to rhabdomyolysis. Fenofibrate is a fibric acid derivative agent that is used in the treatment of hyperlipidaemia. Although several case reports of rhabdomyolysis have been reported due to the combination of statin and fenofibrate, fenofibrate alone rarely causes rhabdomyolysis. When administering fenofibrate in chronic renal failure, dose should be adjusted. Here, we report a case with fenofibrate-induced rhabdomyolysis in a patient with chronic renal failure.
authors.affiliation: Department of Nephrology, University of Yuzuncu Yil, Van, Turkey. yaseminsoyoral@yahoo.com
authors.forename: Yasemin Usul
authors.initials: YU
authors.lastname: Soyoral
authors.forename: Esra Turan
authors.initials: ET
authors.lastname: Canbaz
authors.forename: Mehmet Fatih
authors.initials: MF
authors.lastname: Erdur
authors.forename: Habib
authors.initials: H
authors.lastname: Emre
authors.forename: Huseyin
authors.initials: H
authors.lastname: Begenik
authors.forename: Reha
authors.initials: R
authors.lastname: Erkoc
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D011345:Fenofibrate / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D000960:Hypolipidemic Agents / Q000009:adverse effects; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D012206:Rhabdomyolysis / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000960:Hypolipidemic Agents; D011345:Fenofibrate