title: [Correlation between pulmonary function indexes and survival time in patients with advanced lung cancer].
abstract: BACKGROUND
  To those patients with advanced lung cancer, the ultimate objective is to improve the curative effect and quality of life, lung function indexes are an important factor. We investigate the change of lung function and the relationship between pulmonary function indexs and survival time in patients with advanced lung cancer.
  
  
  METHODS
  Lung function was detected in 59 cases with lung cancer and 63 normal controls. The relationship between pulmonary function indexs and survival time was analyzed.
  
  
  RESULTS
  There was significant difference in ventilation function and diffusing capacity between in lung cancer group and control group. Vital capacity (VC), forced expiratory volume in one second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF), peak expiratory flow% (PEF%), maximal ventilatory volume (MVV) were positively correlated with survival time in patients with advanced lung cancer (r=0.29, 0.28, 0.28, 0.27, 0.26, 0.28, P<0.05), residual volume/total lung capacity was negatively correlated with survival time (r=-0.31, P<0.05).
  
  
  CONCLUSIONS
  The lung function decreases in the patients with lung cancer. VC, FEV1, FVC, PEF, PEF%, MVV, residual volume/total lung capacity were correlated with survival time in patients with advanced lung cancer. The pulmonary function indexs were important marker of prognosis in patients with lung cancer.
authors.affiliation: Department of Respiratory Medicine, Subei People's Hospital of Jiangsu Province, Yangzhou 225001, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Ge
authors.forename: Zhenghua
authors.initials: Z
authors.lastname: Jiang
authors.forename: Qian
authors.initials: Q
authors.lastname: Huang
authors.forename: Muyun
authors.initials: M
authors.lastname: Zhu
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate