title: The vagotomy alleviates the anorectic effect of an excess amount of dietary leucine on rats fed a low-protein diet.
abstract: It is well known that large dose of leucine reduces the food intake and causes growth retardation in experimental animals when leucine is given with a low-protein diet. However, the mechanism for the anorectic effect of leucine has not yet been clarified. We demonstrate here that the anorectic effect of leucine was significantly reduced in a vagotomized rat.
authors.affiliation: Laboratory of Molecular Nutrition, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto 606-8522, Japan.
authors.forename: Ryoji
authors.initials: R
authors.lastname: Yoshimura
authors.forename: Yee Yin
authors.initials: YY
authors.lastname: Ho
authors.forename: Takafumi
authors.initials: T
authors.lastname: Mizushige
authors.forename: Kousaku
authors.initials: K
authors.lastname: Ohinata
authors.forename: Ryuhei
authors.initials: R
authors.lastname: Kanamoto
mesh_terms: D000818:Animals; D001067:Appetite Depressants / Q000494:pharmacology*; D004032:Diet; D018753:Diet, Protein-Restricted / Q000009:adverse effects*; D007930:Leucine / Q000494:pharmacology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D014628:Vagotomy
chemical_list: D001067:Appetite Depressants; D007930:Leucine