title: A covariate-adjusted response-adaptive allocation in clinical trials for a general class of responses.
abstract: A class of covariate-adjusted adaptive allocation procedures is developed for a general class of responses with an aim to satisfy relevant clinical requirements. Some exact and asymptotic properties of the procedures, proposed and a reasonable competitor, are studied and compared under the presence of treatment-covariate interaction.
authors.affiliation: Department of Statistics, University of Calcutta, Kolkata, India.
authors.forename: Uttam
authors.initials: U
authors.lastname: Bandyopadhyay
authors.forename: Rahul
authors.initials: R
authors.lastname: Bhattacharya
mesh_terms: D000328:Adult; D000367:Age Factors; D002986:Clinical Trials as Topic / Q000379:methods*; D003627:Data Interpretation, Statistical; D006801:Humans; D006973:Hypertension / Q000178:diet therapy; D008875:Middle Aged; D012107:Research Design
keywords: covariate-adjusted allocation; ethics; response-adaptive design