title: [Cytoflavin in the detoxification of alcohol-dependent patients].
abstract: Cytoflavin was used in the complex detoxification of 30 alcohol-dependent patients and 30 patients of the comparison group who did not receive this drug. It has been shown that cytoflavin promotes the regression of alcohol withdrawal symptoms, including arterial hypertension, tachycardia, nausea, vomiting, hyperhydrosis, tremor, the severity of head and headache. At the same time, cytoflavin significantly reduces the total score on the CIWA-Ar scale and severity of an autonomic component of pathological alcohol craving to the fifth day of treatment. It has been concluded that cytoflavin is effective and safe for the complex detoxification of alcohol-dependent patients.
authors.forename: A I
authors.initials: AI
authors.lastname: Minko
authors.forename: I V
authors.initials: IV
authors.lastname: Linskiĭ
authors.forename: V N
authors.initials: VN
authors.lastname: Kuz'minov
authors.forename: E S
authors.initials: ES
authors.lastname: Samoĭlova
authors.forename: V V
authors.initials: VV
authors.lastname: Goloshchapov
authors.forename: K A
authors.initials: KA
authors.lastname: Artemchuk
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000188:drug therapy* / Q000378:metabolism; D004338:Drug Combinations; D000431:Ethanol / Q000493:pharmacokinetics*; D005260:Female; D005486:Flavin Mononucleotide / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008658:Inactivation, Metabolic; D007290:Inosine Diphosphate / Q000627:therapeutic use*; D009536:Niacinamide / Q000627:therapeutic use*; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy* / Q000378:metabolism; D013386:Succinates / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D004338:Drug Combinations; D013386:Succinates; C507879:cytoflavin; D009536:Niacinamide; D000431:Ethanol; D005486:Flavin Mononucleotide; D007290:Inosine Diphosphate