title: Corticosteroid Induced, HHV-8 Positive Kaposi's Sarcoma in a Non-HIV Elderly Patient.
abstract: Kaposi's sarcoma (KS) was first described in 1872 by Moritz Kaposi. In 1994, Chang et al. first identified DNA sequences corresponding to human herpesvirus-8 (HHV-8) in AIDS-associated Kaposi sarcoma biopsies. It is now believed that presence of HHV-8 is necessary but not sufficient to cause KS. Other factors like immunosuppressive therapy also play a role. We describe an HIV-negative elderly patient who developed KS of skin and mucous membrane after prolonged use of corticosteroids for knee pain. The patient was positive for HHV-8.
authors.affiliation: Department of Dermatology, Venereology and Leprosy Sheri-Kashmir Institute of Medical Sciences (SKIMS).
authors.forename: Gh Mohiuddin
authors.initials: GM
authors.lastname: Wani
authors.forename: Sheikh Manzoor
authors.initials: SM
authors.lastname: Ahmad
authors.forename: Seema
authors.initials: S
authors.lastname: Qayoom
authors.forename: Bilquees
authors.initials: B
authors.lastname: Khursheed
authors.forename: A R
authors.initials: AR
authors.lastname: Khan
keywords: HHV-8; HIV/AIDS; Kaposi sarcoma; corticosteroids