title: Tolterodine for the treatment of urge urinary incontinence.
abstract: BACKGROUND
  Overactive bladder (OAB) and its resultant urge urinary incontinence (UUI) are significant problems that medically, psychologically and financially affect people. The constellation of symptoms comprising OAB affects ∼ 16% of the adult population and its prevalence increases with aging. The typical class of medications used to treat OAB is antimuscarinics.
  
  
  METHODS
  OAB medications, with a focus on tolterodine for the treatment of UUI are reviewed. A thorough review of English language literature using EMBASE/Medline and PubMed has been performed.
  
  
  CONCLUSIONS
  Tolterodine provides a reasonable starting point when treating patients with OAB and UUI. Efficacy and tolerability are generally comparable between tolterodine and other newer antimuscarinics. Tolterodine is a good option as part of the algorithm in the treatment of OAB and UUI.
authors.affiliation: Weill Cornell Medical College of Cornell University, James Buchanan Brady Department of Urology , 425 East 61st Street, 12th floor, New York, NY 10065 , USA.
authors.forename: Dean S
authors.initials: DS
authors.lastname: Elterman
authors.forename: Bilal
authors.initials: B
authors.lastname: Chughtai
authors.forename: Steven A
authors.initials: SA
authors.lastname: Kaplan
authors.forename: Jack
authors.initials: J
authors.lastname: Barkin
mesh_terms: D001559:Benzhydryl Compounds / Q000494:pharmacology / Q000627:therapeutic use*; D003408:Cresols / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D018727:Muscarinic Antagonists / Q000494:pharmacology / Q000627:therapeutic use*; D010665:Phenylpropanolamine / Q000494:pharmacology / Q000627:therapeutic use*; D000068737:Tolterodine Tartrate; D016896:Treatment Outcome; D053201:Urinary Bladder, Overactive / Q000188:drug therapy*; D053202:Urinary Incontinence, Urge / Q000188:drug therapy*; D064804:Urological Agents / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D001559:Benzhydryl Compounds; D003408:Cresols; D018727:Muscarinic Antagonists; D064804:Urological Agents; D010665:Phenylpropanolamine; D000068737:Tolterodine Tartrate