title: Mitral and tricuspid valve surgery for Coffin-Lowry syndrome.
abstract: Coffin-Lowry syndrome is a rare X-linked disorder characterized by craniofacial and skeletal abnormalities, mental retardation, short stature, and hypotonia. An 18-year-old man with morphologic features characteristic of Coffin-Lowry syndrome was referred to our institution for valve disease surgery for worsening cardiac failure. Echocardiography showed severe mitral valve regurgitation associated with tricuspid valve regurgitation. Mitral valve implantation with a biological valve and tricuspid annular plication with a ring was performed. The ascending aorta was hypoplastic. Both the mitral papillary muscle originating near the mitral annulus and the chordae were shortened. The patient's postoperative course was uneventful and his cardiac failure improved.
authors.affiliation: Cardiovascular Surgery Department, Matsubara Tokushukai Hospital, 7-13-26 Amamihigashi, Matsubara, Osaka, 580-0032, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yoshida
authors.forename: Takeki
authors.initials: T
authors.lastname: Ohashi
authors.forename: Masato
authors.initials: M
authors.lastname: Furui
authors.forename: Souichirou
authors.initials: S
authors.lastname: Kageyama
authors.forename: Noriko
authors.initials: N
authors.lastname: Kodani
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Hirai
authors.forename: Reo
authors.initials: R
authors.lastname: Sakakura
mesh_terms: D000293:Adolescent; D001011:Aorta / Q000601:surgery; D001705:Bioprosthesis; D038921:Coffin-Lowry Syndrome / Q000150:complications*; D004452:Echocardiography / Q000379:methods; D006333:Heart Failure / Q000209:etiology / Q000601:surgery; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000601:surgery; D058386:Mitral Valve Annuloplasty / Q000379:methods*; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000601:surgery*; D010210:Papillary Muscles / Q000002:abnormalities / Q000601:surgery; D014261:Tricuspid Valve / Q000601:surgery; D014262:Tricuspid Valve Insufficiency / Q000150:complications / Q000601:surgery*