title: Straightforward synthesis of dihydrobenzofurans and benzofurans from arynes.
abstract: Synthesis of dihydrobenzofurans was achieved by a route involving the insertion of arynes into formamides followed by trapping with zinc enolates of α-chlorinated methines. Benzofurans were generated from dihydrobenzofurans having a ketone group via the addition of an ethyl anion, the retro-aldol type reaction, and the elimination of an amino group.
authors.affiliation: School of Pharmacy, Hyogo University of Health Sciences, Minatojima, Kobe 650-8530, Japan.
authors.forename: Eito
authors.initials: E
authors.lastname: Yoshioka
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Tanaka
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kohtani
authors.forename: Hideto
authors.initials: H
authors.lastname: Miyabe
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006844:Hydrocarbons, Cyclic / Q000737:chemistry*; D015394:Molecular Structure; D015032:Zinc / Q000737:chemistry*
chemical_list: D001572:Benzofurans; D006844:Hydrocarbons, Cyclic; D015032:Zinc