title: Anaesthesia in children with osteogenesis imperfecta - report of 14 general anaesthetics in three children.
abstract: Osteogenesis imperfecta is a rare, genetically inherited syndrome involving connective tissue. It results in extremely fragile bones and disorders of other organs and body systems. Children with osteogenesis imperfecta are susceptible to bone fractures and often require surgery and anaesthesia. We describe a series of 14 general anaesthetics in three patients suffering from this disease. In one of these cases, perioperative hyperthermia was observed. Anaesthetic management of osteogenesis imperfecta and a possible relationship between this syndrome and malignant and non-malignant hyperthermia are discussed.
authors.affiliation: Department of Anaesthesiology and Intensive Therapy, District Hospital of Orthopaedics and Trauma Surgery in Piekary Śląskie, Poland. oit_urazowy@wp.pl
authors.forename: Ewa
authors.initials: E
authors.lastname: Górnik-Właszczuk
authors.forename: Jacek
authors.initials: J
authors.lastname: Majewski
authors.forename: Rafał
authors.initials: R
authors.lastname: Szczygieł
authors.forename: Andrzej
authors.initials: A
authors.lastname: Dusiel
mesh_terms: D000293:Adolescent; D000768:Anesthesia, General / Q000379:methods*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010013:Osteogenesis Imperfecta / Q000601:surgery*