title: Analysis of 118 pesticides in tobacco after extraction with the modified QuEChRS method by LC-MS-MS.
abstract: A liquid chromatography-tandem quadrupole mass spectrometry (LC-MS-MS) multi-residue method for the simultaneous target analysis of a wide range of pesticides in tobacco has been developed. Gradient elution has been used in conjunction with positive mode electrospray ionization tandem mass spectrometry to detect up to 118 pesticides in tobacco. The recoveries obtained for each pesticide ranged between 70 and 118% at two spiked concentration levels. Good linear relationships were observed with correlation coefficients r(2) > 0.992 for all analytes. The established method was successfully applied to the determination of pesticide residues in real tobacco samples in order to validate the suitability for routine analysis.
authors.affiliation: China National Tobacco Quality Supervision & Test Center, Zhengzhou 450000, PR China.
authors.forename: Fei
authors.initials: F
authors.lastname: Yang
authors.affiliation: China National Tobacco Quality Supervision & Test Center, Zhengzhou 450000, PR China No.2, Fengyang Street, Zhengzhou New & Hi-Tech Industries Development Zone, Henan, China zybian@126.com.
authors.forename: Zhaoyang
authors.initials: Z
authors.lastname: Bian
authors.affiliation: China National Tobacco Quality Supervision & Test Center, Zhengzhou 450000, PR China.
authors.forename: Xiaoshui
authors.initials: X
authors.lastname: Chen
authors.affiliation: China National Tobacco Quality Supervision & Test Center, Zhengzhou 450000, PR China.
authors.forename: Sansan
authors.initials: S
authors.lastname: Liu
authors.affiliation: China National Tobacco Quality Supervision & Test Center, Zhengzhou 450000, PR China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.affiliation: China National Tobacco Quality Supervision & Test Center, Zhengzhou 450000, PR China.
authors.forename: Gangling
authors.initials: G
authors.lastname: Tang
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D010575:Pesticides / Q000032:analysis*; D015203:Reproducibility of Results; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014026:Nicotiana / Q000737:chemistry*
chemical_list: D010575:Pesticides