title: Spectral Doppler analysis of parathyroid adenoma: correlation between resistive index and serum parathyroid hormone concentration.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the correlation between spectral wave analyses by measuring the resistive index and serum intact parathyroid hormone (iPTH) concentration in primary hyperparathyroidism.
  
  
  METHODS
  From March 2008 to April 2012, 46 consecutively registered patients underwent color and spectral Doppler ultrasonography for determination of vascularity and vascular resistance of parathyroid adenoma. The color Doppler sonographic findings were compared with methoxyisobutylisonitrile (MIBI) scintigraphic findings, serum iPTH concentration, and the volume of the gland.
  
  
  RESULTS
  The mean resistive index in parathyroid adenoma was 0.69 ± 0.12. The study showed a strong negative relation between resistive index and serum iPTH concentration. There was a significant negative relation between the volume of the gland and the resistive index.
  
  
  CONCLUSIONS
  There is a relation between degree of perfusion in parathyroid adenoma and serum iPTH concentration. Resistive index may be an objective alternative parameter for determining the vascularity of adenoma for monitoring of response to alcohol ablation therapy and medical management.
authors.affiliation: Department of Radiology, Urmia University of Medical Sciences, Modaress Blvd, Ershad Ave, Urmia, West Azerbaijan, 05555 Iran. Mohamadi_afshin@yahoo.com
authors.forename: Afshin
authors.initials: A
authors.lastname: Mohammadi
authors.forename: Farzad
authors.initials: F
authors.lastname: Moloudi
authors.forename: Mohammad
authors.initials: M
authors.lastname: Ghasemi-rad
mesh_terms: D000236:Adenoma / Q000097:blood* / Q000000981:diagnostic imaging* / Q000601:surgery; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000097:blood / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood*; D010282:Parathyroid Neoplasms / Q000097:blood / Q000000981:diagnostic imaging* / Q000601:surgery; D016105:Parathyroidectomy; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D018615:Ultrasonography, Doppler, Color; D014655:Vascular Resistance
chemical_list: D010281:Parathyroid Hormone