title: eRNAs reach the heart of transcription.
abstract: Recently, various studies shed light on the functional significance of enhancer RNAs. Two recent studies published in Nature by Li et al. and Lam et al. highlight the importance of these newly characterized RNA molecules and their key role in controlling transcriptional programs.
authors.affiliation: 1] Division of Gene Regulation, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands [2] Doctoral Programme in Biomedicine and Experimental Biology, Centre for Neuroscience and Cell Biology, Erasmus MC, Rotterdam University, The Netherlands.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Melo
authors.forename: Nicolas
authors.initials: N
authors.lastname: Léveillé
authors.forename: Reuven
authors.initials: R
authors.lastname: Agami
mesh_terms: D000818:Animals; D015536:Down-Regulation / Q000235:genetics*; D004742:Enhancer Elements, Genetic / Q000235:genetics*; D004967:Estrogens / Q000494:pharmacology*; D006801:Humans; D008264:Macrophages / Q000378:metabolism*; D056953:Nuclear Receptor Subfamily 1, Group D, Member 1 / Q000378:metabolism*; D022661:RNA, Untranslated / Q000235:genetics*; D014158:Transcription, Genetic / Q000235:genetics*; D015533:Transcriptional Activation / Q000187:drug effects*
chemical_list: D004967:Estrogens; D056953:Nuclear Receptor Subfamily 1, Group D, Member 1; D022661:RNA, Untranslated