title: Light activation for the versatile and accurate kinetic analysis of disassembly of self-immolative spacers.
abstract: Three procedures that rely on photoactivation are introduced to accurately analyze the disassembly kinetics of a collection of self-immolative spacer groups within the window 10(-2)-10(3) s. Our results are relevant for deriving quantitative structure-property relationships. In particular, we have been able to access 20 ms temporal resolution, which made possible the measurement of the shortest ever reported disassembly time for an activated self-immolative spacer.
authors.affiliation: Institut Curie, Centre de Recherche, 26 rue d'Ulm, 75248 Paris, France.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Alouane
authors.forename: Raphaël
authors.initials: R
authors.lastname: Labruère
authors.forename: Thomas
authors.initials: T
authors.lastname: Le Saux
authors.forename: Isabelle
authors.initials: I
authors.lastname: Aujard
authors.forename: Sylvie
authors.initials: S
authors.lastname: Dubruille
authors.forename: Frédéric
authors.initials: F
authors.lastname: Schmidt
authors.forename: Ludovic
authors.initials: L
authors.lastname: Jullien
keywords: disassembly; fluorescence; kinetics; photochemistry; self-immolation