title: [Vitreomacular adhesion in HD-OCT images in the age-related macular degeneration].
abstract: OBJECTIVE
  The aim of this study was to evaluate an incidence of the vitreomacular adhesion in patients with age-related macular degeneration.
  
  
  METHODS
  We examined 472 eyes in 241 patients (136 W/ 105 M) in age of 54-92 years (mean 62.6 years +/- 8.5) with dry or wet age-related macular degeneration using Cirrus HD-OCT (Zeiss) macular cube 512x128 program or 5-line pro-gram.
  
  
  RESULTS
  Vitreomacular adhesion was observed in 139 eyes with dry age-related macular degeneration (29.4%, p=0.000*), in 101 eyes with drusen (21.4%, p=0.000*), in 38 eyes with retinal pigment epithelium alterations (8%, p=0.202), in 278 eyes with wet age-related macular degeneration (58.9%, p=0.001*), in 21 eyes with pigment epithelial detachment (4.4%, p=0.303), in 161 eyes with choroidal neovascularzation (34. 1%, p=0.031*/ and in 96 eyes with scar (20.4%, p=0.040*).
  
  
  CONCLUSIONS
  Probably, vitreomacular adhesion alone is not able to induce age-related macular degeneration, but it may be associated with choroidal neovascularization development, it can contribute to exudate formation and choroidal neovascularization, it may induces or sustains a chronic low-grade inflammation in the macula region.
authors.affiliation: Klinika Chirurgii Siatk6wki i Ciała Szklistego Katedry Okulistyki Uniwersytetu Medycznego w Lublinie Kierownik. mlatalska@o2.pl
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Latalska
authors.forename: Anna
authors.initials: A
authors.lastname: Swiech-Zubilewicz
authors.forename: Jerzy
authors.initials: J
authors.lastname: Mackiewicz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015984:Causality; D020256:Choroidal Neovascularization / Q000453:epidemiology* / Q000473:pathology*; D015897:Comorbidity; D005260:Female; D006801:Humans; D015994:Incidence; D008266:Macula Lutea / Q000473:pathology*; D008268:Macular Degeneration / Q000453:epidemiology* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy / Q000706:statistics & numerical data; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D000267:Tissue Adhesions / Q000453:epidemiology / Q000473:pathology; D041623:Tomography, Optical Coherence / Q000706:statistics & numerical data; D014822:Vitreous Body / Q000473:pathology*