title: [Cervical cancer--possibilities of detection of human papillomavirus].
abstract: OBJECTIVE
  To describe the possibility of detection of HPV DNA in cervical cancer.
  
  
  METHODS
  Review.
  
  
  METHODS
  Institute of Molecular and Translational Medicine, Laboratory of Experimental Medicine, Palacky University and University Hospital Olomouc.
  
  
  METHODS
  Human papillomavirus (HPV) is the cause of many cancers, especially cervical cancer. Current cervical cancer screening is based on cytological examination, which is followed by HPV DNA diagnostics only in cases with abnormal results of uncertain significance. Methods used for HPV detection are often based on PCR reaction followed by genotyping (complete or partial). HPV DNA diagnostics isn´t currently included into the primary cervical cancer screening in the Czech Republic although it has higher sensitivity than cytology.
  
  
  CONCLUSIONS
  Inclusion of HPV DNA testing into the primary cervical cancer screening would significantly increase its sensitivity and thus would help to reduce the morbidity and mortality of this disease in Czech population.
authors.affiliation: Laboratoř experimentální medicíny, Ústav molekulární a translační medicíny, LF UP a FN, Olomouc. ondryasova.hana@gmail.com
authors.forename: H
authors.initials: H
authors.lastname: Ondryášová
authors.forename: V
authors.initials: V
authors.lastname: Koudeláková
authors.forename: M
authors.initials: M
authors.lastname: Hajdúch
mesh_terms: D018153:Czech Republic; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000821:virology*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000821:virology*