title: [Potential applications of beta-elemene in anti-atherosclerosis and anti-restenosis].
abstract: It is well known that beta-elemene is a broadly effective antitumor drug. In recent years, many studies suggested that beta-elemene also has potential value in the treatment of atherosclerosis and restenosis. In this paper, the effect of beta-elemene in inhibition of angiogenesis, inhibition of thrombus formation, improvement of hemorheology, protection against oxidative injuries, anti-inflammation and suppression of restenosis after percutaneous transluminal coronary angioplasty (PTCA) are summarized and reviewed.
authors.affiliation: Key Laboratory of Biorheological Science and Technology, Ministry of Education, Chongqing Engineering Laboratory in Vascular Implants, Bioengineering College of Chongqing University, Chongqing 400044, China.
authors.forename: Qinglei
authors.initials: Q
authors.lastname: Dong
authors.forename: Tieying
authors.initials: T
authors.lastname: Yin
authors.forename: Guixue
authors.initials: G
authors.lastname: Wang
mesh_terms: D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D050197:Atherosclerosis / Q000517:prevention & control*; D023903:Coronary Restenosis / Q000517:prevention & control*; D006801:Humans; D012717:Sesquiterpenes / Q000494:pharmacology*
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D012717:Sesquiterpenes; C445979:beta-elemene