title: [Characterization of a probiotic Lactobacillus strain isolated from oral cavity].
abstract: OBJECTIVE
  From oral cavity we isolated and characterized probiotic lactobacilli that could probability be applied to therapy and prevention of oral diseases.
  
  
  METHODS
  Lactobacillus strains were isolated by plating the saliva and dental plaque of healthy donors on selective medium. Then the target strains were tested for inhibiting the growth of a Streptococcus mutans strain belonging to cariogenic pathogen species. Other properties such as production of extracellular polysaccharide and resistance to the antibacterial substances were also investigated.
  
  
  RESULTS
  Lactobacillus fermentum Y29, a strain with antimicrobial activity against Streptococcus mutans, was obtained from dental plaque. This strain was an extracellular polysaccharide producer, which corresponds to its aggregation ability. Moreover, L. fermentum Y29 showed resistance to 1.0 mg/mL lysozyme and 140 microg/g hydrogen peroxide that may guarantee its persistence in the complex oral niche.
  
  
  CONCLUSIONS
  Probiotic properties were characterized of an oral isolate L. fermentum Y29, which provided a possibility for its application in prevention and treatment of oral diseases.
authors.affiliation: Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China. wwwyangjie3436@126.com
authors.forename: Juan
authors.initials: J
authors.lastname: Yang
authors.forename: Guocheng
authors.initials: G
authors.lastname: Du
authors.forename: Jian
authors.initials: J
authors.lastname: Chen
authors.forename: Fang
authors.initials: F
authors.lastname: Fang
mesh_terms: D003773:Dental Plaque / Q000382:microbiology*; D052197:Limosilactobacillus fermentum / Q000187:drug effects / Q000302:isolation & purification* / Q000378:metabolism / Q000502:physiology*; D009055:Mouth / Q000382:microbiology*; D019936:Probiotics; D012463:Saliva / Q000382:microbiology*; D013295:Streptococcus mutans / Q000378:metabolism