title: Inversion of enantioselectivity of a mononuclear non-heme iron(II)-dependent hydroxylase by tuning the interplay of metal-center geometry and protein structure.
authors.affiliation: Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, Petersgasse 12, 8010 Graz, Austria.
authors.forename: Sarah M
authors.initials: SM
authors.lastname: Pratter
authors.forename: Cornelia
authors.initials: C
authors.lastname: Konstantinovics
authors.forename: Cristiana M L
authors.initials: CM
authors.lastname: Di Giuro
authors.forename: Erich
authors.initials: E
authors.lastname: Leitner
authors.forename: Devesh
authors.initials: D
authors.lastname: Kumar
authors.forename: Sam P
authors.initials: SP
authors.lastname: de Visser
authors.forename: Gideon
authors.initials: G
authors.lastname: Grogan
authors.forename: Grit D
authors.initials: GD
authors.lastname: Straganz
mesh_terms: D055162:Biocatalysis; D018360:Crystallography, X-Ray; D006900:Hydroxylation; D007501:Iron / Q000737:chemistry*; D007700:Kinetics; D006899:Mixed Function Oxygenases / Q000737:chemistry* / Q000378:metabolism; D017434:Protein Structure, Tertiary; D013237:Stereoisomerism
chemical_list: D007501:Iron; D006899:Mixed Function Oxygenases
keywords: asymmetric catalysis; hydroxylation; metalloenzymes; non-heme iron; protein design