title: In situ self-folding assembly of a multi-walled hydrogel tube for uniaxial sustained molecular release.
abstract: This study presents a multi-walled poly(ethylene glycol) diacrylate hydrogel tube formed by the simple self-folding of a bi-layered hydrogel patch. The gel tube has the capability to release encapsulated molecules through designated pathways in a sustained manner. Therefore, the gel tube encapsulating the vascular endothelial growth factor significantly increases the vascular densities and vessel diameters at an implantation site.
authors.affiliation: Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, 61801, USA.
authors.forename: Kwanghyun
authors.initials: K
authors.lastname: Baek
authors.forename: Jae Hyun
authors.initials: JH
authors.lastname: Jeong
authors.forename: Artem
authors.initials: A
authors.lastname: Shkumatov
authors.forename: Rashid
authors.initials: R
authors.lastname: Bashir
authors.forename: Hyunjoon
authors.initials: H
authors.lastname: Kong
mesh_terms: D000818:Animals; D002417:Cattle; D004337:Drug Carriers / Q000737:chemistry*; D020100:Hydrogels / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry; D012710:Serum Albumin, Bovine / Q000737:chemistry; D042461:Vascular Endothelial Growth Factor A / Q000737:chemistry
chemical_list: D004337:Drug Carriers; D020100:Hydrogels; D042461:Vascular Endothelial Growth Factor A; C437167:poly(ethylene glycol)diacrylate; D012710:Serum Albumin, Bovine; D011092:Polyethylene Glycols
keywords: angiogenesis; drug delivery; expansion ratio; neovascularization; self-folding