title: [Research progress in sperm mediated gene transfer technology].
abstract: With the rapid development of biotechnology, we can change the trait of organism using transgenetic technology. In recent years, there are growing interests in the establishment of sperm mediated gene transfer (SMGT) technology as an effective and convenient method to produce transgenic animals. SMGT technology is a transgenetic method, which is easy in operation and does little harm to the cell compared with the other transgenetic methods. In this review, we expound the background, development, mechanism, operation and application of SMGT.
authors.affiliation: Company Four, Third Military Medical University, Chongqing 400038, China.
authors.forename: Xiaoxiong
authors.initials: X
authors.lastname: Hao
authors.forename: Zheng
authors.initials: Z
authors.lastname: Zhu
authors.forename: Mianfu
authors.initials: M
authors.lastname: Cao
authors.forename: Chengren
authors.initials: C
authors.lastname: Li
authors.forename: Yunlai
authors.initials: Y
authors.lastname: Lin
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D018014:Gene Transfer Techniques; D005818:Genetic Engineering / Q000379:methods*; D008297:Male; D013083:Sperm Transport / Q000502:physiology; D013094:Spermatozoa / Q000378:metabolism* / Q000502:physiology