title: Intracerebral and spinal cord syphilitic gummata in an HIV-negative man: a case report.
abstract: We present a case of an HIV-negative individual who presented with worsening central and peripheral neurological symptoms and signs. Clinical, serological, histopathological, and radiological features were in keeping with concurrent cerebral and spinal cord syphilitic gummata, a tertiary manifestation of syphilis. Clinical improvement occurred after treatment of neurosyphilis.
authors.affiliation: Department of Sexual Health and HIV, Whittall Street Clinic, University Hospitals Birmingham NHS Foundation Trust, Whittall Street, Birmingham, UK. divya.dhasmana@nhs.net
authors.forename: Divya
authors.initials: D
authors.lastname: Dhasmana
authors.forename: Jaishree
authors.initials: J
authors.lastname: Joshi
authors.forename: Kaveh
authors.initials: K
authors.lastname: Manavi
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D018023:HIV Seronegativity; D006801:Humans; D007262:Infusions, Intravenous; D008279:Magnetic Resonance Imaging; D008297:Male; D009494:Neurosyphilis / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D010400:Penicillin G / Q000008:administration & dosage / Q000627:therapeutic use*; D013116:Spinal Cord / Q000382:microbiology / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D010400:Penicillin G