title: Effect of whole-body vibration exercise on mobility, balance ability and general health status in frail elderly patients: a pilot randomized controlled trial.
abstract: OBJECTIVE
  To study the effects of whole-body vibration exercises on the mobility function, balance and general health status, and its feasibility as an intervention in frail elderly patients.
  
  
  METHODS
  Pilot randomized controlled trial.
  
  
  METHODS
  Forty-four frail older persons (85.27 ± 3.63 years) meeting the Fried Frailty Criteria.
  
  
  METHODS
  All eligible subjects were randomly assigned to the experimental group, who received a whole-body vibration exercise alone (vibration amplitude: 1-3 mm; frequency: 6-26 Hz; 4-5 bouts × 60 seconds; 3-5 times weekly), or a control group, who received usual care and exercises for eight weeks.
  
  
  METHODS
  The Timed Up and Go Test, 30-second chair stand test, lower extremities muscle strength, balance function, balance confidence and General Health Status were assessed at the beginning of the study, after four weeks and eight weeks of the intervention.
  
  
  RESULTS
  Whole-body vibration exercise reduced the time of the Timed Up and Go Test (40.47 ± 15.94 s to 21.34 ± 4.42 s), improved the bilateral knees extensor strength (6.96 ± 1.70 kg to 11.26 ± 2.08 kg), the posture stability (surface area ellipse: 404.58 ± 177.05 to 255.95 ± 107.28) and General Health Status (Short-form Health Survey score: 24.51 ± 10.69 and 49.63 ± 9.85 to 45.03 ± 11.15 and 65.23 ± 9.39, respectively). The repeated-measures ANOVA showed that there were significant differences in the Timed Up and Go Test, 30-second chair stand test, bilateral knees extensor strength, activities-specific balance confidence score and general health status between the two groups (P < 0.05). No side-effects were observed during the training.
  
  
  CONCLUSIONS
  Whole-body vibration exercise is a safe and effective method that can improve the mobility, knee extensor strength, balance and the general health status in the frail elderly.
authors.affiliation: 1Department of Rehabilitation Medicine, Nan Lou of Chinese PLA General Hospital, Beijing, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Changshui
authors.initials: C
authors.lastname: Weng
authors.forename: Miao
authors.initials: M
authors.lastname: Liu
authors.forename: Qiuhua
authors.initials: Q
authors.lastname: Wang
authors.forename: Liming
authors.initials: L
authors.lastname: Liu
authors.forename: Yao
authors.initials: Y
authors.lastname: He
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D016330:Frail Elderly; D006304:Health Status; D006801:Humans; D008297:Male; D009068:Movement / Q000502:physiology*; D010865:Pilot Projects; D004856:Postural Balance / Q000502:physiology*; D014732:Vibration / Q000627:therapeutic use*
keywords: Whole-body vibration; balance; elderly; exercise; frail elderly; health status; lower extremity; mechanical oscillation; muscle strength; musculoskeletal system