title: Construction of quaternary stereocenters: asymmetric α-amination of branched aldehydes catalyzed by monoimide substituted cyclohexane-1,2-diamines.
abstract: A highly efficient enantioselective α-amination of branched aldehydes catalyzed by chiral imide monosubstituted 1,2-diamine derivatives was reported to afford the quaternary stereogenic centers in excellent yields (up to 99%) and enantioselectivities (up to 97% ee). Chirality 25:668-672, 2013. © 2013 Wiley Periodicals, Inc.
authors.affiliation: Key Laboratory of Asymmetric Synthesis and Chirotechnology of Sichuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, P.R. China; College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan, P.R. China.
authors.forename: Ji-Ya
authors.initials: JY
authors.lastname: Fu
authors.forename: Qi-Lin
authors.initials: QL
authors.lastname: Wang
authors.forename: Lin
authors.initials: L
authors.lastname: Peng
authors.forename: Yong-Yuan
authors.initials: YY
authors.lastname: Gui
authors.forename: Xiao-Ying
authors.initials: XY
authors.lastname: Xu
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Wang
keywords: asymmetric amination; branched aldehydes; primary amine