title: Glutamine, glucose and other fuels for cancer.
abstract: Tumor cells suffer a metabolic reprogramming which allows them to use metabolic fuels (glucose, glutamine, lipids) through anabolic fates to support their enhanced proliferation and other carcinogenesis-related features. The present review tries to address and summarize the broad and growing information available about this reprogramming, whose pieces, put together, make up a complex scheme that encompasses different complexity scales, from cells to systemic networks.
authors.forename: Maria Victoria
authors.initials: MV
authors.lastname: Ruiz-Perez
authors.forename: Francisca
authors.initials: F
authors.lastname: Sanchez-Jimenez
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Alonso
authors.forename: Juan A
authors.initials: JA
authors.lastname: Segura
authors.forename: Javier
authors.initials: J
authors.lastname: Marquez
authors.affiliation: Department of Molecular Biology and Biochemistry, Faculty of Sciences, University of Malaga, Malaga, Spain. mariaviruiz@uma.es.
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: Medina
mesh_terms: D000641:Ammonia / Q000378:metabolism; D000818:Animals; D002952:Citric Acid Cycle; D005947:Glucose / Q000378:metabolism*; D005972:Glutaminase / Q000378:metabolism; D005973:Glutamine / Q000378:metabolism*; D006019:Glycolysis; D006801:Humans; D009369:Neoplasms / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D016160:Retinoblastoma Protein / Q000502:physiology
chemical_list: D016160:Retinoblastoma Protein; D005973:Glutamine; D000641:Ammonia; C586504:GLS2 protein, human; D005972:Glutaminase; D005947:Glucose