title: Balloon dilatation of anastomotic strictures secondary to surgical repair of oesophageal atresia: a systematic review.
abstract: Surgical repair of oesophageal atresia may result in anastomotic strictures. These strictures are often treated by balloon dilatation (BD) and currently balloon dilatation (fluoroscopic or endoscopic) is the preferred primary treatment method. Here we review the current evidence of the outcomes of balloon dilatation of anastomotic strictures secondary to surgical repair of oesophageal atresia. We searched the standard databases (January, 1960-May, 2012) to identify all studies that reported outcomes of balloon dilatation of anastomotic strictures secondary to surgical repair of oesophageal atresia in children. Data, reported as median (range), were analysed and compared. Outcomes were success of BD, number of BD sessions, number of oesophageal perforations, need for other surgical interventions and mortality. Five studies were found to be relevant (n = 139; 81 [58%] male children). The total number of dilatation sessions was 401 (2.9 dilatations per child patient). General anaesthesia was used in two (40%) studies; sedation in a further two (40%) studies and one (20%) study used a combination of both. The size of balloon catheter ranged from 4 mm to 22 mm. Seven perforations were reported (1.8% per dilatation session), of which only one (14%) required surgery. No deaths were recorded. Balloon dilatation for anastomotic strictures post-EA repair is safe, and associated with a low perforation and mortality rates. Most perforations are amenable to conservative management.
authors.affiliation: Surgery Unit, UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK. m.thyoka@ucl.ac.uk
authors.forename: Mandela
authors.initials: M
authors.lastname: Thyoka
authors.forename: Antonia
authors.initials: A
authors.lastname: Timmis
authors.forename: Tumpale
authors.initials: T
authors.lastname: Mhango
authors.forename: Derek J
authors.initials: DJ
authors.lastname: Roebuck
mesh_terms: D000800:Angioplasty, Balloon; D002404:Catheterization / Q000401:mortality*; D015984:Causality; D015897:Comorbidity; D004106:Dilatation / Q000401:mortality; D004933:Esophageal Atresia / Q000401:mortality* / Q000601:surgery*; D004939:Esophageal Perforation / Q000000981:diagnostic imaging / Q000401:mortality*; D004940:Esophageal Stenosis / Q000401:mortality* / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications / Q000401:mortality*; D015995:Prevalence; D011859:Radiography; D012307:Risk Factors; D015996:Survival Rate