title: Co-infections with Ureaplasma parvum, Mycoplasma hominis and Chlamydia trachomatis in a human immunodeficiency virus positive woman with vaginal discharge.
abstract: A 30-year-old human immunodeficiency virus (HIV)-1 infected woman presented with vaginal discharge and associated vulval irritation. The vaginal swabs tested positive for Ureaplasma parvum and Mycoplasma hominis by both culture and polymerase chain reaction (PCR). The specimen also tested positive for Chlamydia trachomatis deoxyribonucleic acid (DNA) by cryptic plasmid and omp1 gene PCR assays. The patient was successfully treated with azithromycin based on the antibiotic susceptibility testing results of U. parvum and M. hominis by microbroth dilution. Since sexually transmitted infections enhance the transmission of HIV, HIV-positive patients should be screened routinely for these pathogens.
authors.affiliation: Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Arnab
authors.initials: A
authors.lastname: Ghosh
authors.forename: Jyoti
authors.initials: J
authors.lastname: Rawre
authors.forename: Neena
authors.initials: N
authors.lastname: Khanna
authors.forename: Benu
authors.initials: B
authors.lastname: Dhawan
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D017963:Azithromycin / Q000494:pharmacology / Q000627:therapeutic use; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D060085:Coinfection / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008826:Microbial Sensitivity Tests; D008828:Microbiological Techniques; D009175:Mycoplasma Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D019535:Mycoplasma hominis / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D014509:Ureaplasma / Q000302:isolation & purification; D016869:Ureaplasma Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D019522:Vaginal Discharge / Q000175:diagnosis* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin