title: Prediction of the mesiodistal size of unerupted canines and premolars for a group of Romanian children: a comparative study.
abstract: OBJECTIVE
  The aim of the present study was to develop an optimization method of multiple linear regression equation (MLRE), using a genetic algorithm to determine a set of coefficients that minimize the prediction error for the sum of permanent premolars and canine dimensions in a group of young people from a central area of Romania represented by a city called Sibiu.
  
  
  METHODS
  To test the proposed method, we used a multiple linear regression equation derived from the estimation method proposed by Mojers, to which we adjusted regression coefficients using the Breeder genetic algorithm. A total of 92 children were selected with complete permanent teeth with no clinically visible dental caries, proximal restorations or orthodontic treatment. A hard dental stone was made for each of these models, which was then measured with a digital caliper. The Dahlberg analyses of variance had been performed to determine the error of method, then the Correlation t Test was applied, and finally the MLRE equations were obtained using the version 16 for Windows of the SPSS program.
  
  
  RESULTS
  The correlation coefficient of MLRE was between 51-67% and the significance level was set at α=0.05. Comparing predictions provided by the new and respectively old method, we can conclude that the Breeder genetic algorithm is capable of providing the best values for parameters of multiple linear regression equations, and thus our equations are optimized for the best performance.
  
  
  CONCLUSIONS
  The prediction error rates of the optimized equations using the Breeder genetic algorithm are smaller than those provided by the multiple linear regression equations proposed in the recent study.
authors.affiliation: Department of Preventive Dentistry, College of Medicine V. Papilian, Lucian Blaga University of Sibiu, Sibiu, Romania. boitorcornel@yahoo.com
authors.forename: Cornel Gheorghe
authors.initials: CG
authors.lastname: Boitor
authors.forename: Florin
authors.initials: F
authors.lastname: Stoica
authors.forename: Hamdan
authors.initials: H
authors.lastname: Nasser
mesh_terms: D000293:Adolescent; D000465:Algorithms; D001641:Bicuspid / Q000033:anatomy & histology*; D002648:Child; D003481:Cuspid / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D009811:Odontometry / Q000379:methods*; D009929:Organ Size; D011237:Predictive Value of Tests; D012016:Reference Values; D015203:Reproducibility of Results; D012383:Romania; D014097:Tooth, Unerupted / Q000033:anatomy & histology*