title: A new cycloartane nortriterpenoid from stem and leaf of Quercus variabilis.
abstract: A new compound 3-acetyloxy-epicycloeucalenol-24-one (1), with 11 known compounds 3α-acetyloxy-4α,14α-dimethyl-9β,19-cycloergost-24-oic acid (2), 3-epicycloeucalenol (3), 3-epicycloeucalenyl-24-one (4), 3-epicycloeucalenyl acetate (5), 4β,14α-dimethyl-5α-ergosta-9β,19-cyclo-24(31)-en-3β-hydroxy-4α-carboxylic acid (6), cycloeucalenone (7), friedelin (8), epifriedelanol (9), lup-20 (29)-en-3β,30-diol (10), betulin (11), lupeol (12), was isolated from the stems and leaves of Quercus variabilis Blume. Seven compounds (1-7) showed anti-inflammatory activity.
authors.affiliation: a School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang , 110016 , China.
authors.forename: Ling-Yun
authors.initials: LY
authors.lastname: Jia
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Chong-Ning
authors.initials: CN
authors.lastname: Lv
authors.forename: Tan-Ye
authors.initials: TY
authors.lastname: Xu
authors.forename: Ben-Zhi
authors.initials: BZ
authors.lastname: Jia
authors.forename: Jin-Cai
authors.initials: JC
authors.lastname: Lu
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004423:Ear / Q000473:pathology; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D051379:Mice; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D029963:Quercus / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014992:Xylenes / Q000633:toxicity; D000094062:Betulinic Acid; D000094042:Lupanes
chemical_list: D000893:Anti-Inflammatory Agents; D004365:Drugs, Chinese Herbal; D009828:Oleanolic Acid; D014315:Triterpenes; D014992:Xylenes; C585799:3-acetyloxy-epicycloeucalenol-24-one; C472599:cycloeucalenone; C055670:friedelinol; C085352:cycloartane; C002503:betulin; D000094062:Betulinic Acid; C060796:friedelin; D000094042:Lupanes