title: Greasing the SCIDs for universal flu antibodies.
abstract: In this issue, Nakamura et al. (2013) describe a robust SCID mouse-based method for isolating human monoclonal antibodies of desired specificity from adoptively transferred human B cells. As proof of principle, they isolate human mAbs that could potentially be used to treat or prevent human infection with any influenza A virus strain.
authors.affiliation: Laboratory of Viral Diseases, NIAID, Bethesda, MD 20892, USA. jyewdell@nih.gov
authors.forename: Jonathan W
authors.initials: JW
authors.lastname: Yewdell
authors.forename: William L
authors.initials: WL
authors.lastname: Ince
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D005260:Female; D006801:Humans; D009980:Influenza A virus / Q000276:immunology*; D007251:Influenza, Human / Q000188:drug therapy*; D008297:Male; D009500:Neutralization Tests / Q000379:methods*; D010950:Plasma Cells / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral