title: Chemotherapy-related gallbladder visualization in a 99mTc-HMDP SPECT/CT bone scan.
abstract: Nonosseous uptakes are occasionally found on bone scintigraphy. Most of them are easily explained by current pathophysiological mechanisms (metastatic calcifications, metabolic process, or extravascular accumulation of radiopharmaceutical) or current artifacts. Other unusual findings are still unexplained. We report 1 didactic case of incidental gallbladder uptake on bone scan. Additional single-photon emission computed tomography-computed tomography (SPECT/CT) imaging was performed to better characterize abnormal location. The significance of this serendipitous uptake is not clearly established. This finding could be due to altered distribution induced by the chemotherapy regimen and is not the result of intrinsic gallbladder disease.
authors.affiliation: From the *Department of Nuclear Medicine Lumen, and University Claude Bernard Lyon, Lyon; †INSERM U1028-CNRS UMRS5292, Lyon; and ‡EA 3738, Faculté Charles Mérieux Lyon Sud, Lyon, France.
authors.forename: Juliette
authors.initials: J
authors.lastname: Bozzetto
authors.forename: Sophie
authors.initials: S
authors.lastname: Lancelot
authors.forename: Francesco
authors.initials: F
authors.lastname: Giammarile
mesh_terms: D016477:Artifacts; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging*; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008875:Middle Aged; D013669:Technetium Tc 99m Medronate / Q000031:analogs & derivatives*; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: C024226:technetium Tc 99m hydroxymethylene diphosphonate; D013669:Technetium Tc 99m Medronate