title: The occurrence of endometriosis with ovarian carcinomas is not purely coincidental.
abstract: OBJECTIVE
  To explore the association between epithelial ovarian cancer (EOC) and common benign gynecological disorders.
  
  
  METHODS
  The medical records of 226 patients with EOC treated at Peking Union Medical College Hospital between March 2011 and March 2012 were reviewed. Histological evaluations had been performed to determine the presence of coexisting pelvic endometriosis (n=17), uterine leiomyoma (n=66), adenomyosis (n=22), or endometrial polyps (n=17).
  
  
  RESULTS
  Coexistence of endometriosis occurred in 35.3% and 36.4% of cases of the clear cell and endometrioid subtypes of EOC histology, respectively. Endometriosis was more likely associated with clear cell or endometrioid ovarian carcinoma, but less likely with high grade serous cancer. No differences were observed in the concurrence of uterine myoma, adenomyosis or endometrial polyps among the different subtypes of EOC.
  
  
  CONCLUSIONS
  In contrast to other common benign gynecological disorders, endometriosis showed close relationships with the clear cell and endometrioid subtypes of EOC specifically.
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, PR China.
authors.forename: Lin
authors.initials: L
authors.lastname: Qiu
authors.forename: Shu
authors.initials: S
authors.lastname: Wang
authors.forename: Jing He
authors.initials: JH
authors.lastname: Lang
authors.forename: Keng
authors.initials: K
authors.lastname: Shen
authors.forename: Hui Fang
authors.initials: HF
authors.lastname: Huang
authors.forename: Ling Ya
authors.initials: LY
authors.lastname: Pan
authors.forename: Ming
authors.initials: M
authors.lastname: Wu
authors.forename: Jia Xin
authors.initials: JX
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000453:epidemiology / Q000209:etiology*; D002681:China / Q000453:epidemiology; D004715:Endometriosis / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies; D014591:Uterine Diseases / Q000150:complications* / Q000453:epidemiology; D055815:Young Adult
keywords: Endometriosis; Epithelial ovarian carcinoma; Histology