title: Problem-based test: replication of mitochondrial DNA during the cell cycle.
abstract: Terms to be familiar with before you start to solve the test: cell cycle, generation time, S-phase, cell culture synchronization, isotopic pulse-chase labeling, density labeling, equilibrium density-gradient centrifugation, buoyant density, rate-zonal centrifugation, nucleoside, nucleotide, kinase enzymes, polymerization of nucleic acids, re-replication block, cell fractionation, Svedberg (sedimentation constant = [ S]), nuclear DNA, mitochondrial DNA, heavy and light mitochondrial DNA chains, heteroplasmy, mitochondrial diseases
authors.affiliation: Department of Medical Biology, Medical School, University of Pécs, H-7624 Pécs, Hungary. gyorgy.setalo.jr@aok.pte
authors.forename: György
authors.initials: G
authors.lastname: Sétáló
mesh_terms: D001671:Biochemistry / Q000193:education*; D002453:Cell Cycle; D002499:Centrifugation, Density Gradient; D004261:DNA Replication; D004272:DNA, Mitochondrial; D004521:Educational Measurement / Q000379:methods*; D009626:Terminology as Topic
chemical_list: D004272:DNA, Mitochondrial