title: [A case of brain abscess secondary to bisphosphonate-related osteonecrosis of the jaws in metastatic bone lesions from breast carcinoma].
abstract: Bisphosphonates have been used clinically as highly effective drugs in the treatment of hypercalcemia of malignancy, and bone metastasis of solid cancers. Despite these benefits, however, the emergence of bisphosphonate-related osteonecrosis of the jaws has become a growing and significant problem in a subset of patients receiving these drugs. We report a rare case of brain abscess secondary to BRONJ in metastatic bone lesions from breast carcinoma.
authors.affiliation: Dept. of Surgery, Sakai Municipal Hospital, Japan.
authors.forename: Ako
authors.initials: A
authors.lastname: Matsushita
authors.forename: Shunji
authors.initials: S
authors.lastname: Kamigaki
authors.forename: Yukio
authors.initials: Y
authors.lastname: Nakamura
mesh_terms: D000328:Adult; D001922:Brain Abscess / Q000209:etiology*; D001943:Breast Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D004164:Diphosphonates / Q000009:adverse effects* / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007573:Jaw Neoplasms / Q000188:drug therapy / Q000556:secondary*; D010020:Osteonecrosis / Q000139:chemically induced* / Q000601:surgery
chemical_list: D004164:Diphosphonates