title: Current treatment of low grade gliomas.
abstract: Low grade gliomas affect predominantly young adults, and have a relatively favorable prognosis compared to grade III and grade IV gliomas. The challenge for an optimal management of these patients is to find the balance between an optimal survival and the preservation of neurological function including cognition. Because all medical treatments may induce side effects, in young and nearly asymptomatic patients the choices can be difficult. This review summarizes the current strategies: a watch-and-wait policy, surgery, chemotherapy, and radiotherapy.
authors.affiliation: Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands ; Daniel den Hoed Oncology Center, Neuro-Oncology Unit, PO Box 5201, 3008 AE Rotterdam, The Netherlands.
authors.forename: Martin J
authors.initials: MJ
authors.lastname: van den Bent
authors.forename: Tom J
authors.initials: TJ
authors.lastname: Snijders
authors.forename: Jacoline E C
authors.initials: JE
authors.lastname: Bromberg
keywords: Astrocytoma; Chemotherapy; Low grade glioma; Oligodendroglioma; Radiotherapy; Surgery; Temozolomide