title: Non-melanoma skin cancer incidence and impact of skin cancer screening on incidence.
abstract: Non-melanoma skin cancer (NMSC) is the most common malignancy, whose public health significance is often unrecognized. This analysis has two objectives: first, to provide up-to-date incidence estimates by sex, age group, histological type, and body site; and second, to study the impact of skin cancer screening. The impact of screening on NMSC incidence in Schleswig-Holstein, Germany, is analyzed by comparing four time periods of different screening settings (no screening (1998-2000), pilot project (Skin Cancer Research to Provide Evidence for Effectiveness of Screening in Northern Germany, SCREEN, 2003-2004), after SCREEN (2004-2008), and nation-wide skin cancer screening (2008-2010)) to a reference region (Saarland, Germany). Age-standardized (Europe) NMSC incidence was 119/100,000 for women and 145/100,000 for men in the most recent screening period in Schleswig-Holstein (2008-2010). During implementation of SCREEN (2003-2004), incidence increased from 81.5/100,000 to 111.5/100,000 (1998-2000) by 47% for women and 34% for men. All age groups in women were affected by the increase, but increases for men were mostly limited to the older age groups. Incidence in Saarland first increased slowly, but increased steeply with the introduction of the nation-wide skin cancer screening in 2008 (+47% for women and +40% for men, reference 2004-2008). Observed changes are most likely attributed to screening activities.
authors.affiliation: Institute of Cancer Epidemiology, University of Luebeck, Luebeck, Germany. Electronic address: nora.eisemann@krebsregister-sh.de.
authors.forename: Nora
authors.initials: N
authors.lastname: Eisemann
authors.affiliation: Institute of Social Medicine and Epidemiology, University Hospital Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.
authors.forename: Annika
authors.initials: A
authors.lastname: Waldmann
authors.affiliation: Department of Social and Behavioral Sciences, Harvard School of Public Health, Boston, Massachusetts, USA.
authors.forename: Alan C
authors.initials: AC
authors.lastname: Geller
authors.affiliation: Dermatoepidemiology Unit, VA Medical Center Providence, Providence, Rhode Island, USA; Department of Dermatology, Rhode Island Hospital, Providence, Rhode Island, USA; Departments of Dermatology and Epidemiology, Brown University, Providence, Rhode Island, USA.
authors.forename: Martin A
authors.initials: MA
authors.lastname: Weinstock
authors.affiliation: Center of Dermatology, Elbe Clinics, Buxtehude, Germany.
authors.forename: Beate
authors.initials: B
authors.lastname: Volkmer
authors.affiliation: Center of Dermatology, Elbe Clinics, Buxtehude, Germany.
authors.forename: Ruediger
authors.initials: R
authors.lastname: Greinert
authors.affiliation: Center of Dermatology, Elbe Clinics, Buxtehude, Germany; Association of Dermatological Prevention (ADP) e. V., Hamburg, Germany.
authors.forename: Eckhard W
authors.initials: EW
authors.lastname: Breitbart
authors.affiliation: Institute of Cancer Epidemiology, University of Luebeck, Luebeck, Germany; Institute of Social Medicine and Epidemiology, University Hospital Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Katalinic
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D015266:Carcinoma, Merkel Cell / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D055088:Early Detection of Cancer / Q000706:statistics & numerical data*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012509:Sarcoma / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control; D017678:Sex Distribution; D012878:Skin Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control