title: Low-level laser therapy and vibration therapy for the treatment of localized adiposity and fibrous cellulite.
abstract: BACKGROUND
  In recent years, there has been an upsurge in the application of low-level laser therapy in various medical diseases. Additionally, vibration therapy is a new and effective measure to prevent muscular atrophy and osteoporosis, along with some general health-related beneficial effects of exercise on skeletal muscles such as improvement of endothelial function and an increased enzyme capacity of energy metabolism. The aim of this study was to evaluate the application of a 635 nm and 0.040 W exit power per multiple diode laser in combination with vibration therapy for the application of non-invasive reduction of circumference in patients with localized adiposity and cellulite.
  
  
  METHODS
  The study enrolled men and women (N = 33) aged 18-64 years with localized adiposity or fibrous cellulite. The evaluation parameters were: photographic evaluation, perimetric evaluation, blood tests, ecographic evaluation, histological evaluation, and subjective and objective tests.
  
  
  RESULTS
  The results produced were statistically analyzed and resulted in a significant reduction of fat thickness when compared to the measurement prior to the treatment (P < 0.0001). Moreover, subjective and objective tests, as well as ecographic and histological evaluations, confirmed the reduction of fat thickness.
  
  
  CONCLUSIONS
  In this study we have demonstrated the safety and efficacy of the combination between low-level laser therapy and vibration therapy for the resolution of localized adiposity and fibrous cellulite.
authors.affiliation: Promoitalia Group S.p.A, Pozzuoli, Naples Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Savoia
authors.forename: Simone
authors.initials: S
authors.lastname: Landi
authors.forename: Fulvio
authors.initials: F
authors.lastname: Vannini
authors.forename: Alfonso
authors.initials: A
authors.lastname: Baldi
keywords: Body contouring; Fibrous cellulite; Localized adiposity; Low-level laser therapy; Ultrasound; Vibration therapy