title: Vulvar histoplasmosis as a rare cause of genital ulceration.
abstract: BACKGROUND
  Histoplasmosis is an infection caused by the dimorphic fungus Histoplasma capsulatum and primarily presents with pulmonary symptoms. Immunocompromised individuals are at high risk for contracting disseminated histoplasmosis, which can be fatal if left untreated.
  
  
  METHODS
  We present a case involving a 50-year-old woman with acquired immunodeficiency syndrome with an ulcerated vulvar lesion concerning for carcinoma. Extensive workup revealed disseminated histoplasmosis without pulmonary manifestations. She was treated with an extended course of an antifungal agent. Her vulvar lesion resolved.
  
  
  CONCLUSIONS
  Vulvar histoplasmosis is a rare etiology of vulvar pathology but one that should be considered in immunocompromised patients.
authors.affiliation: Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama.
authors.forename: Megan M
authors.initials: MM
authors.lastname: Shine
authors.forename: Monjri M
authors.initials: MM
authors.lastname: Shah
authors.forename: Courtney A
authors.initials: CA
authors.lastname: Hanna
authors.forename: Kerri S
authors.initials: KS
authors.lastname: Bevis
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000382:microbiology*; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D005260:Female; D006658:Histoplasma; D006660:Histoplasmosis / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008875:Middle Aged; D014456:Ulcer / Q000188:drug therapy / Q000382:microbiology*; D014845:Vulvar Diseases / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B