title: Low-contrast agent dose dual-energy CT monochromatic imaging in pulmonary angiography versus routine CT.
abstract: OBJECTIVE
  This study aimed to retrospectively evaluate the feasibility and reliability of low-contrast agent dose dual-energy computed tomography (DECT) monochromatic imaging in pulmonary angiography.
  
  
  METHODS
  Computed tomography pulmonary angiography was performed in 86 patients, 41 in 120-kVp computed tomography (CT) and 45 in DECT with low-contrast agent dose. The images in DECT were reconstructed at optimal kiloelectron-voltage (keV), demonstrating the best contrast-to-noise ratio between pulmonary artery and soft tissue, and at 70 keV. Image quality was compared by quantitative and subjective indexes. The radiation doses were recorded.
  
  
  RESULTS
  Compared with 120-kVp CT, optimal keV showed superior quantitative indexes with inferior subjective image quality, whereas 70 keV demonstrated no statistical difference in quantitative indexes with superior subjective image quality. All suspicious pulmonary embolisms in DECT were diagnosed confidently by combination of 2 kinds of monochromatic imaging. The radiation dose in DECT is almost twice as 120-kVp CT.
  
  
  CONCLUSIONS
  Low-contrast agent dose DECT monochromatic imaging in pulmonary angiography accommodates superior intravascular enhancement and contrast in pulmonary arteries, and improves diagnostic confidence with compatible radiation dose.
authors.affiliation: Department of Radiology, Peking University First Hospital, Beijing, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Dong
authors.forename: Xiaoying
authors.initials: X
authors.lastname: Wang
authors.forename: Xuexiang
authors.initials: X
authors.lastname: Jiang
authors.forename: Li
authors.initials: L
authors.lastname: Gao
authors.forename: Feiyu
authors.initials: F
authors.lastname: Li
authors.forename: Jianxing
authors.initials: J
authors.lastname: Qiu
authors.forename: Yufeng
authors.initials: Y
authors.lastname: Xu
authors.forename: He
authors.initials: H
authors.lastname: Wang
mesh_terms: D000368:Aged; D000792:Angiography / Q000379:methods*; D003287:Contrast Media / Q000008:administration & dosage*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007483:Iothalamic Acid / Q000008:administration & dosage*; D008297:Male; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging*; D015900:Radiography, Dual-Energy Scanned Projection / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007483:Iothalamic Acid