title: Discrepancy between preoperative imaging and surgical findings in patients with advanced ovarian cancer: a study of initial false-negative lesions.
abstract: OBJECTIVE
  The objective of this study was to determine the patterns of erroneous interpretation of preoperative computed tomography (CT) for detection of peritoneal lesions in advanced ovarian cancer.
  
  
  METHODS
  Between 2007 and 2011, 148 patients with International Federation of Gynecology and Obstetrics stage IIIC-IV ovarian cancer, who underwent multi-detector-row CT before primary cytoreduction, were enrolled. We reviewed the preoperative CT and compared the findings with the surgical findings. For the discrepant cases, false-negative cases were reevaluated after revealing of surgical findings and were categorized as either absence or presence of lesion (missed case). We performed region-based comparisons according to predefined peritoneal lesion locations.
  
  
  RESULTS
  Sixty-eight false-negative cases were identified, of which 43 were revealed to be initially missed cases. The most common locations were found to be the small-bowel mesentery (21%), subdiaphragmatic space (19%), and porta hepatis (16%).
  
  
  CONCLUSIONS
  The missed peritoneal implants commonly resided in the same sites of preoperative imaging criteria that could predict suboptimal primary cytoreduction.
authors.affiliation: Department of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Seok Min
authors.initials: SM
authors.lastname: Ko
authors.forename: Dae Chul
authors.initials: DC
authors.lastname: Jung
authors.forename: Young Taik
authors.initials: YT
authors.lastname: Oh
authors.forename: Sun Ho
authors.initials: SH
authors.lastname: Kim
authors.forename: Sokbom
authors.initials: S
authors.lastname: Kang
mesh_terms: D005188:False Negative Reactions; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000453:epidemiology; D010537:Peritoneum / Q000000981:diagnostic imaging* / Q000601:surgery*; D011300:Preoperative Care; D015995:Prevalence; D019736:Prostheses and Implants / Q000706:statistics & numerical data*; D011859:Radiography; D015203:Reproducibility of Results; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D018570:Risk Assessment; D012680:Sensitivity and Specificity