title: [A case of bipolar I disorder with autistic disorder showing "waiting-for-instruction" as a depressive symptom].
abstract: We have experienced a case of bipolor I disorder complicated by mental retardation and autistic disorder. Acquired daily life activities such as eating, clothing and toileting without assistance were gradually lost during depressive periods, which was consistent with the previous reports. Before losing daily life skills, the patient could no longer perform daily life activities without consecutive instructions. This "waiting-for-instruction" behavior may be an early diagnostic key for major depressive episode in mentally-retarded children and adolescents.
authors.affiliation: Division of Clinical Nursing, Yamagata University School of Nursing, Yamagata. schumann@med.id.yamagata-u.ac.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yokoyama
authors.forename: Mieko
authors.initials: M
authors.lastname: Hirose
authors.forename: Chieko
authors.initials: C
authors.lastname: Nara
authors.forename: Keisuke
authors.initials: K
authors.lastname: Wakusawa
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kubota
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Haginoya
authors.forename: Shigeru
authors.initials: S
authors.lastname: Tsuchiya
authors.forename: Kazuie
authors.initials: K
authors.lastname: Iinuma
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D001321:Autistic Disorder / Q000150:complications* / Q000175:diagnosis; D001714:Bipolar Disorder / Q000175:diagnosis / Q000628:therapy*; D003863:Depression / Q000150:complications* / Q000175:diagnosis; D042241:Early Diagnosis; D006801:Humans; D008607:Intellectual Disability / Q000150:complications* / Q000175:diagnosis; D008297:Male