title: Clinical and oncological outcomes after surgical excision of parotid gland tumours in patients aged over 80 years.
abstract: The objective of this study was to evaluate the surgical and long-term outcomes of a series of patients aged over 80 years, operated on for parotid neoplasms. Among 614 parotidectomies for neoplasms performed between 1998 and 2008, 34 patients (5.5%) aged over 80 years were identified retrospectively. Pathological examination showed a malignant tumour in 24 and a benign tumour in 10 cases. Overall survival (OS) and disease-free survival (DFS) were determined by Kaplan-Meier analysis. A search for parameters that could influence the postoperative complication rate and long-term outcomes was carried out by univariate analysis. There was no postoperative death. Eight patients (24%) had postoperative complications. Malignant histopathology (P=0.05) and radical resection (P=0.033) were found to have a significant negative impact on the postoperative course. Focusing on malignant tumours, only histopathological type (metastasis vs primary tumour) was found to have a negative impact on OS. The 2- and 5-year OS rates were 86% and 86%, respectively, for primary tumours, and 67% and 29%, respectively, for metastasis (P=0.05). Malignant or benign histopathology had no impact on OS. Our results showed acceptable clinical and long-term oncological outcomes in very elderly patients operated on for parotid tumours, including malignant tumours.
authors.affiliation: Service d'ORL et de Chirurgie Cervico-Faciale, Centre Hospitalier Universitaire La Timone, Marseille, France. Electronic address: nicolas.fakhry@ap-hm.fr.
authors.forename: N
authors.initials: N
authors.lastname: Fakhry
authors.forename: B
authors.initials: B
authors.lastname: Aldosari
authors.forename: J
authors.initials: J
authors.lastname: Michel
authors.forename: R
authors.initials: R
authors.lastname: Giorgi
authors.forename: C
authors.initials: C
authors.lastname: Collet
authors.forename: L
authors.initials: L
authors.lastname: Santini
authors.forename: A
authors.initials: A
authors.lastname: Giovanni
authors.forename: P
authors.initials: P
authors.lastname: Dessi
mesh_terms: D000369:Aged, 80 and over; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D009364:Neoplasm Recurrence, Local; D010307:Parotid Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: age; cancer; elderly; salivary glands; surgery