title: A prospective observational study of paediatric cardiac surgery outcomes in a postoperative intensive care unit in Iran.
abstract: OBJECTIVE
  To evaluate the incidence of complications, morbidity and mortality, and the associated risk factors with mortality at a Paediatric Cardiology Intensiv Care Unit of a developing country.
  
  
  METHODS
  The prospective observational study was conducted at Shahid Modarres Hospital, Tehran, Iran, from August 2009 to July 2010. A total of 202 patients were monitored from the time they entered the Paediatric Cardiology Intensive Care Unit till their final discharge. SPSS 16 was used for statistical analysis and p < or = 0.05 was considered statistically significant.
  
  
  RESULTS
  Of the total, 107 (53%) were male and 95 (47%) were female. The mean age of the patients was 4.5 +/- 4.9 years (range: 2 days to 18 years). Among the patients 59 (29.2%) had complications and 25 (12.37%) of them died. A total of 177 (87.6%) survived and were discharged. Infants (p = 0.012), cyanotic congenital heart disease (p = 0.002), longer duration of cardiopulmonary bypass (p = 0.027), longer aortic cross-clamp time (p = 0.038), longer mechanical ventilation time (p < 0.006), and early post-operative period (p = 0.05) were associated factors for mortality. According to regression analysis, cyanotic congenital heart disease, longer intubation time, and early post-operative period were major factors for mortality (p = 0.01, p < 0.001, and p = 0.001) respectively.
  
  
  CONCLUSIONS
  Critically ill cyanotic young infants in the first 24 hours after operation experienced high mortality. Prolonged mechanical ventilation was also associated with high mortality.
authors.affiliation: Department of Paediatric Cardiology and Paediatric Cardiac Surgery, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. roodpeyma_shahla@yahoo.com
authors.forename: Shahla
authors.initials: S
authors.lastname: Roodpeyma
authors.forename: Manuchehr
authors.initials: M
authors.lastname: Hekmat
authors.forename: Maryam
authors.initials: M
authors.lastname: Dordkhar
authors.forename: Sima
authors.initials: S
authors.lastname: Rafieyian
authors.forename: Arash
authors.initials: A
authors.lastname: Hashemi
mesh_terms: D000293:Adolescent; D006348:Cardiac Surgical Procedures / Q000009:adverse effects* / Q000401:mortality*; D002648:Child; D002675:Child, Preschool; D003422:Critical Care; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications / Q000401:mortality* / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015278:Intensive Care Units, Pediatric; D007492:Iran; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome