title: Two new antioxidant diarylheptanoids from the fruits of Alpinia oxyphylla.
abstract: Two new diarylheptanoids, 1-(3',5'-dihydroxy-4'-methoxyphenyl)-7-phenyl-3-heptanone (1) and 1-(2',4'-dihydroxy-3'-methoxyphenyl)-7-(4″-methoxyphenyl)-3-heptanone (2), along with known diarylheptanoid yakuchinone A (3), and five flavanoids, tectochrysin (4), chrysin (5), izalpinin (6), kaempferol 7, 4'-dimethyl ether (7), and kaempferide (8) were isolated from the fruits of Alpinia oxyphylla Miq. Their structures were determined by means of spectroscopic methods. Antioxidant activities of all the isolated compounds were evaluated using a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Compounds 1-3 and 6-8 exhibited potent antioxidant activities in the DPPH assay.
authors.affiliation: a Department of Pharmacy , Yancheng Institute of Health Science , Yancheng , 224005 , China.
authors.forename: Qing-Ya
authors.initials: QY
authors.lastname: Bian
authors.forename: Shi-Yun
authors.initials: SY
authors.lastname: Wang
authors.forename: Li-Jia
authors.initials: LJ
authors.lastname: Xu
authors.forename: Chi-On
authors.initials: CO
authors.lastname: Chan
authors.forename: Daniel K W
authors.initials: DK
authors.lastname: Mok
authors.forename: Si-Bao
authors.initials: SB
authors.lastname: Chen
mesh_terms: D032429:Alpinia / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000494:pharmacology; D036381:Diarylheptanoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D005638:Fruit / Q000737:chemistry; D006139:Guaiacol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D044949:Kaempferols / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010851:Picrates / Q000494:pharmacology
chemical_list: C585999:1-(2',4'-dihydroxy-3'-methoxyphenyl)-7-(4'-methoxyphenyl)-3-heptanone; C585998:1-(3',5'-dihydroxy-4'-methoxyphenyl)-7-phenyl-3-heptanone; D000975:Antioxidants; D001713:Biphenyl Compounds; D036381:Diarylheptanoids; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D044949:Kaempferols; D010851:Picrates; C043561:chrysin; D006139:Guaiacol; C006552:kaempferol; C042566:yakuchinone-A; C402729:tectochrysin; C004931:1,1-diphenyl-2-picrylhydrazyl