title: Rocuronium anaphylaxis in a 3-year-old girl with no previous exposure to neuromuscular blocking agents.
abstract: During the perioperative period, anaphylactic reactions rarely occur. Neuromuscular blocking agents (NMBAs) are responsible for 60-70% of perioperative anaphylactic reactions. This case, we report a case of rocuronium-induced anaphylaxis in a 3-year-old girl with no previous exposure to NMBAs. This case cautions and informs practitioners that an IgE-mediated anaphylactic reaction with rocuronium is possible even in young children with no previous exposure to NMBAs.
authors.affiliation: Department of Pediatrics, School of Medicine, Kyung Hee University, Seoul, Republic of Korea. chsh0414@khu.ac.kr
authors.forename: Sun-Hee
authors.initials: SH
authors.lastname: Choi
authors.forename: Jae-Woo
authors.initials: JW
authors.lastname: Yi
authors.forename: Yeong-Ho
authors.initials: YH
authors.lastname: Rha
mesh_terms: D000707:Anaphylaxis / Q000097:blood* / Q000139:chemically induced* / Q000276:immunology; D000732:Androstanols / Q000008:administration & dosage / Q000009:adverse effects*; D002675:Child, Preschool; D004342:Drug Hypersensitivity / Q000097:blood* / Q000276:immunology; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood* / Q000276:immunology; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage / Q000009:adverse effects*; D000077123:Rocuronium
chemical_list: D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D007073:Immunoglobulin E; D000077123:Rocuronium