title: Stent-assisted coiling in endovascular treatment of 500 consecutive cerebral aneurysms with long-term follow-up.
abstract: OBJECTIVE
  Stent-assisted coil embolization has become one of the most preferred techniques in the treatment of wide-neck intracranial aneurysms; however, long-term patency and safety of the self-expanding neurostents and their role in durability of the endovascular treatment has remained ambiguous. We sought to retrospectively examine the long-term results of self-expanding stent usage in conjunction with coil embolization in treatment of wide-neck cerebral aneurysms.
  
  
  METHODS
  We coiled 500 wide-neck cerebral aneurysms with different types of self-expanding neurostent assistance in 468 patients. Patient and aneurysm characteristics, pharmacologic therapy protocol, complications, and initial occlusion grades were analyzed. Patients underwent angiographic follow-up at 6 months to 7 years after treatment. DSA or MRA images of all patients were analyzed to assess the occlusion rate of aneurysms and patency of the parent artery.
  
  
  RESULTS
  Enterprise (n = 340), Solitaire (n = 98), Wingspan (n = 41), LEO (n = 16), and Neuroform (n = 5) stent systems were used in this series. Stent-related thromboembolic events occurred in 21 patients and intraoperative rupture occurred in 4 patients. Initially, complete occlusion was achieved in 42.2% of the aneurysms, and, according to the last follow-up data, the rate had progressed to 90.8%. Recanalization rate at 6 months was 8%, whereas the late recanalization rate was 2%.
  
  
  CONCLUSIONS
  The use of stents in endovascular treatment provides high rates of complete occlusion and low rates of recurrence at a long-term follow-up study.
authors.affiliation: Department of Radiology, Hacettepe University Hospitals, Ankara, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Geyik
authors.forename: K
authors.initials: K
authors.lastname: Yavuz
authors.forename: N
authors.initials: N
authors.lastname: Yurttutan
authors.forename: I
authors.initials: I
authors.lastname: Saatci
authors.forename: H S
authors.initials: HS
authors.lastname: Cekirge
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001807:Blood Vessel Prosthesis / Q000009:adverse effects / Q000706:statistics & numerical data*; D002533:Cerebral Angiography / Q000706:statistics & numerical data; D002548:Cerebral Revascularization / Q000009:adverse effects / Q000706:statistics & numerical data*; D002648:Child; D015897:Comorbidity; D019544:Equipment Failure Analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis / Q000401:mortality* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000401:mortality*; D015995:Prevalence; D011474:Prosthesis Design; D012307:Risk Factors; D015607:Stents / Q000009:adverse effects / Q000706:statistics & numerical data*; D013923:Thromboembolism / Q000175:diagnosis / Q000209:etiology / Q000401:mortality*; D016896:Treatment Outcome; D014421:Turkey / Q000453:epidemiology; D055815:Young Adult