title: Effects of calcitonin and calcium medication in treatment of edentulous osteoporotic mandible.
abstract: OBJECTIVE
  In addition to damage of the bones that support the remaining teeth, degradation of osteoporotic oral bones also lead to a consequent reduction of supporting tissues and the loss of dentures retention. The aim of this study was to assess the clinical and radiographic outcomes following injection of a calcitonin and calcium solution into the buccal aspects of edentulous mandibles.
  
  
  METHODS
  The experimental group of 67 edentulous patients diagnosed with osteoporosis, and the control group of 19 nonosteoporotic edentulous patients were treated with the calcitonin and calcium once solution per month. Mandibular bone density was measured from panoramic radiographs, supplemented by T scores of skeletal density in the experimental group.
  
  
  RESULTS
  After the therapy, measurements showed moderate increases in bone density, compensating for up to 4% of the total loss of minerals and solidity of denture-bearing areas of osteoporotic mandibles. Osteoporosis affected women earlier than men in this study.
  
  
  CONCLUSIONS
  Application of a calcitonin and calcium solution is a suitable method of preprosthetic therapy for edentulous osteoporotic patients.
authors.affiliation: Clinic of Dental Prosthetic, Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia. srdjan.postic@stomf.bg.ac.rs
authors.forename: Srdjan D
authors.initials: SD
authors.lastname: Postic
mesh_terms: D015502:Absorptiometry, Photon; D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density / Q000187:drug effects; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002116:Calcitonin / Q000008:administration & dosage / Q000627:therapeutic use*; D002118:Calcium / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging*; D008875:Middle Aged; D009066:Mouth, Edentulous / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D010024:Osteoporosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011862:Radiography, Panoramic; D016896:Treatment Outcome
chemical_list: D050071:Bone Density Conservation Agents; D002116:Calcitonin; D002118:Calcium