title: Detection of human taeniases in Tibetan endemic areas, China.
abstract: Detection of taeniasis carriers of Taenia solium is essential for control of cysticercosis in humans and pigs. In the current study, we assessed the positive detection rate of a self-detection tool, stool microscopy with direct smear and coproPCR for taeniasis carriers in endemic Tibetan areas of northwest Sichuan. The self-detection tool through questioning about a history of proglottid expulsion within the previous one year showed an overall positive detection rate of more than 80% for Taenia saginata, T. solium and T. asiatica. The positive detection rate was similar for T. saginata and T. solium. In 132 taeniid tapeworm carriers, 68 (51·5%) were detected by microscopy and 92 (69·7%) were diagnosed by coproPCR. A combination of microscopy and coproPCR increased the positive detection rate to 77·3%. There remained 10 cases (7·6%) coproPCR negative but microscopy positive. Due to the high cost and complicated process, coproPCR is required for the identification of Taenia species only when necessary, though it had a significant higher positive detection rate than microscopy. Combined use of self-detection and stool microscopy are recommended in community-based mass screening for taeniases in this Tibetan area or in other situation-similar endemic regions.
authors.affiliation: Institute of Parasitic Diseases, Sichuan Centers for Disease Control and Prevention, Chengdu 610041, Sichuan, China.
authors.forename: Tiaoying
authors.initials: T
authors.lastname: Li
authors.forename: Xingwang
authors.initials: X
authors.lastname: Chen
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yanagida
authors.forename: Hao
authors.initials: H
authors.lastname: Wang
authors.forename: Changping
authors.initials: C
authors.lastname: Long
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Sako
authors.forename: Munehir
authors.initials: M
authors.lastname: Okamoto
authors.forename: Yunfei
authors.initials: Y
authors.lastname: Wu
authors.forename: Patrick
authors.initials: P
authors.lastname: Giraudoux
authors.forename: Francis
authors.initials: F
authors.lastname: Raoul
authors.forename: Agathe
authors.initials: A
authors.lastname: Nkouawa
authors.forename: Minoru
authors.initials: M
authors.lastname: Nakao
authors.forename: Philip S
authors.initials: PS
authors.lastname: Craig
authors.forename: Akira
authors.initials: A
authors.lastname: Ito
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D002353:Carrier State / Q000175:diagnosis* / Q000453:epidemiology; D002648:Child; D059026:Diagnostic Self Evaluation; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D008853:Microscopy; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D013552:Swine; D013621:Taenia / Q000235:genetics / Q000302:isolation & purification*; D041202:Taenia saginata / Q000235:genetics / Q000302:isolation & purification*; D041201:Taenia solium / Q000235:genetics / Q000302:isolation & purification*; D013622:Taeniasis / Q000175:diagnosis* / Q000453:epidemiology; D018609:Tibet / Q000453:epidemiology