title: miRNAs in development and pathogenesis of the nervous system.
abstract: The human nervous system expresses approximately 70% of all miRNAs (microRNAs). Changing levels of certain ubiquitous and brain-specific miRNAs shape the development and function of the nervous system. It is becoming clear that misexpression of some miRNAs can contribute towards neurodevelopmental disorders. In the present article, we review the current knowledge of the role of miRNAs in development and pathogenesis of the nervous system.
authors.affiliation: Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, UK.
authors.forename: Jakub S
authors.initials: JS
authors.lastname: Nowak
authors.forename: Gracjan
authors.initials: G
authors.lastname: Michlewski
mesh_terms: D000328:Adult; D006801:Humans; D035683:MicroRNAs / Q000502:physiology*; D009420:Nervous System / Q000196:embryology* / Q000254:growth & development; D009422:Nervous System Diseases / Q000503:physiopathology*; D055495:Neurogenesis; D009473:Neuronal Plasticity
chemical_list: D035683:MicroRNAs