title: Nonarteriosclerotic vascular disease.
abstract: Thromboangiitis obliterans, or Buerger disease, is a chronic nonatherosclerotic endarteritis manifesting as inflammation and thrombosis of distal extremity small and medium-sized arteries resulting in relapsing episodes of distal extremity ischemia. Takayasu arteritis is a rare syndrome characterized by inflammation of the aortic arch, pulmonary, coronary, and cerebral vessels, presenting with cerebrovascular symptoms, myocardial ischemia, or upper extremity claudication in young, often female, patients. Kawasaki disease is a small- and medium-vessel acute systemic vasculitis of young children, with morbidity and mortality stemming from coronary artery aneurysms. Microscopic polyangiitis, Churg-Strauss syndrome, and Wegener granulomatosis are systemic small-vessel vasculitides, affecting arterioles, capillary beds and venules, and each presenting with variable effects on the pulmonary, renal and gastrointestinal systems.
authors.affiliation: Division of Vascular Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
authors.forename: William
authors.initials: W
authors.lastname: Wu
authors.forename: Rabih A
authors.initials: RA
authors.lastname: Chaer
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001706:Biopsy / Q000379:methods; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D002317:Cardiovascular Agents / Q000627:therapeutic use; D003097:Collateral Circulation / Q000502:physiology; D003952:Diagnostic Imaging / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D015424:Reperfusion / Q000379:methods; D012307:Risk Factors; D016896:Treatment Outcome; D014657:Vasculitis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones; D002317:Cardiovascular Agents
keywords: Giant cell arteritis; Kawasaki disease; Polyarteritis nodosa; Radiation arteritis; Raynaud phenomenon; Small-vessel vasculitides; Takayasu autoimmune arteritis; Thromboangiitis obliterans