title: [Non-surgical treatment for adenoidal hypertrophy].
abstract: OBJECTIVE
  Study the practicability of non-surgical treatment for adenoidal hypertrophy.
  
  
  METHODS
  Fifty-seven children were recruited in a randomized,placebo-controlled trial. Group T1 underwent intranasal corticosteroids treatment, group T2 underwent leukotriene receptor antagonists treatment, group C underwent placebo treatment:the records of 3 groups were analyzed.
  
  
  RESULTS
  After a 12-week treatment with intranasal corticosteroids or leukotriene receptor antagonists, group T1 and T2 patients demonstrated significant improvements in clinical symptoms and a more-pronounced reduction in adenoid size compared with control group patients, the difference was statistically significant. No statistically significant difference in group T1 and T2 patients.
  
  
  CONCLUSIONS
  Intranasal corticosteroids and leukotriene receptor antagonists may be considered useful in decreasing adenoid pad size and the severity of symptoms related to adenoidal hypertrophy. Children with adenoidal hypertrophy should be considered for non-surgical treatment before surgery is planned.
authors.affiliation: Department of Otolaryngology, Nanjing Children's Hospital Affiliated to Nanjing Medical University, Nanjing, 210008, China. llxuu@sina.com
authors.forename: Xu
authors.initials: X
authors.lastname: Li
authors.forename: Qun
authors.initials: Q
authors.lastname: Huang
mesh_terms: D000234:Adenoids / Q000473:pathology*; D000281:Administration, Intranasal; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000188:drug therapy*; D020024:Leukotriene Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male
chemical_list: D000305:Adrenal Cortex Hormones; D020024:Leukotriene Antagonists