title: Patient-reported outcomes in Spanish patients diagnosed with bilateral age-related macular degeneration.
abstract: OBJECTIVE
  To evaluate the patient-reported outcomes (PRO) in age-related macular degeneration (AMD) patients by using instruments for eliciting health status and vision specific issues.
  
  
  METHODS
  PRO were assessed using the 25-item National Eye Institute Visual Function Questionnaire (NEIVFQ-25) and the Short-Form General Health Survey (SF-12).
  
  
  RESULTS
  The mean age and corrected distance visual acuity (CDVA) in the better eye of the AMD patients were 82.53 ± 5.17 years and 0.82 ± 0.43 logMAR, respectively. The overall NEIVFQ-25 composite score was 57.89. SF-12 physical and mental component summary scores were 37.28 and 57.25, respectively. There were significant correlations (p ≤ 0.05) between CDVA and the following NEIVFQ-25 subscales: general (r = -0.73), near (r = -0.40) and distance vision (r = -0.60), role limitations (r = -0.40), social function (r = -0.48) and mental health (r = -0.38).
  
  
  CONCLUSIONS
  Visual function is severely affected in AMD patients. It hampers their daily living without, however, deeply disturbing their social function. This may help them retain adequate mental health despite their poor physical status.
authors.affiliation: IOBA Eye Institute, University of Valladolid, Valladolid, Spain.
authors.forename: Alberto
authors.initials: A
authors.lastname: López-Miguel
authors.forename: María B
authors.initials: MB
authors.lastname: Coco-Martín
authors.forename: Rosa
authors.initials: R
authors.lastname: Martínez-Fernández
authors.forename: Ana M
authors.initials: AM
authors.lastname: Gómez-Ramírez
authors.forename: Diego
authors.initials: D
authors.lastname: García-Ayuso
authors.forename: Paloma
authors.initials: P
authors.lastname: Sobrado-Calvo
authors.forename: Miguel J
authors.initials: MJ
authors.lastname: Maldonado
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004185:Disability Evaluation; D005260:Female; D006304:Health Status; D006306:Health Surveys; D006801:Humans; D008268:Macular Degeneration / Q000175:diagnosis / Q000503:physiopathology*; D008297:Male; D018434:Sickness Impact Profile; D013030:Spain; D011795:Surveys and Questionnaires; D014786:Vision Disorders / Q000175:diagnosis / Q000503:physiopathology*; D014792:Visual Acuity / Q000502:physiology*; D019987:Persons with Visual Disabilities