title: Role of biopsy in low-grade laryngeal chondrosarcoma: report of two cases.
abstract: Laryngeal chondrosarcomas are rare tumours that account for less than 1% of all sarcomas and originate principally from the crycoid cartilage. We report two cases: the former arising from thyroid cartilage in an 85-year-old male presenting with a palpable neck mass and hoarseness, dyspnoea and dysphagia; the other in a 54-year-old male with a mass growing from crycoid cartilage, who underwent biopsy followed by total laryngectomy. We discuss the peculiarity of the site of origin and the role of biopsy, the clinical presentation of the former case and the diagnostic and therapeutic procedures of the latter. Since it is a rare form of sarcoma arising in the larynx, we discuss the role of biopsy as a crucial although still controversial diagnostic tool.
authors.affiliation: Division of Pathology, Bollate e Garbagnate Milanese, A.O.G. Salvini, Garbagnate Milanese, Milan, Italy. monica.onorati@libero.it
authors.forename: M
authors.initials: M
authors.lastname: Onorati
authors.forename: L
authors.initials: L
authors.lastname: Moneghini
authors.forename: A
authors.initials: A
authors.lastname: Maccari
authors.forename: M
authors.initials: M
authors.lastname: Albertoni
authors.forename: I
authors.initials: I
authors.lastname: Talamo
authors.forename: F
authors.initials: F
authors.lastname: Ferrario
authors.forename: G
authors.initials: G
authors.lastname: Bulfamante
authors.forename: S
authors.initials: S
authors.lastname: Romagnoli
authors.forename: F
authors.initials: F
authors.lastname: Di Nuovo
mesh_terms: D000369:Aged, 80 and over; D001706:Biopsy; D002813:Chondrosarcoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006685:Hoarseness / Q000209:etiology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D013957:Thyroid Cartilage / Q000473:pathology / Q000601:surgery