title: Parathyrsoidins A-D, four new sesquiterpenoids from the soft coral Paralemnalia thyrsoides.
abstract: Four new nardosinane-type sesquiterpenoids, parathyrsoidins A-D (1-4) were isolated from the soft coral Paralemnalia thyrsoides. The structures of parathyrsoidins A-D (1-4) were determined by extensive spectral analysis and their cytotoxicity against selected cancer cell lines as well as antiviral activity against human cytomegalovirus (HCMV) were evaluated in vitro.
authors.affiliation: Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. pit0424@yahoo.com.tw
authors.forename: Yen-Ju
authors.initials: YJ
authors.lastname: Tseng
authors.forename: Yu-Sheng
authors.initials: YS
authors.lastname: Lee
authors.forename: Shang-Kwei
authors.initials: SK
authors.lastname: Wang
authors.forename: Jyh-Horng
authors.initials: JH
authors.lastname: Sheu
authors.forename: Chang-Yih
authors.initials: CY
authors.lastname: Duh
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology; D001685:Biological Factors / Q000737:chemistry* / Q000494:pharmacology; D045744:Cell Line, Tumor; D003587:Cytomegalovirus / Q000187:drug effects; D006801:Humans; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry*
chemical_list: D000998:Antiviral Agents; D001685:Biological Factors; D012717:Sesquiterpenes