title: Drug and disease model resources: a consortium to create standards and tools to enhance model-based drug development.
abstract: Model-based drug development (MBDD) is accepted as a vital approach in understanding patients' drug-related benefit and risk by integrating quantitative information integration from diverse sources collected throughout drug development.(1) This perspective introduces the activities of the Drug and Disease Model Resources (DDMoRe) consortium, founded in 2011 through the Innovative Medicines Initiative Joint Undertaking (IMI-JU)(2) as a European public-private partnership to address a lack of common tools, languages, and standards for modeling and simulation (M&S) to improve model-based knowledge integration.CPT: Pharmacometrics & Systems Pharmacology (2013) 2, e34; doi:10.1038/psp.2013.10; advance online publication 20 March 2013.
authors.affiliation: Clinical Pharmacology/Pharmacometrics, Pfizer, Sandwich, UK.
authors.forename: L
authors.initials: L
authors.lastname: Harnisch
authors.forename: I
authors.initials: I
authors.lastname: Matthews
authors.forename: J
authors.initials: J
authors.lastname: Chard
authors.forename: M O
authors.initials: MO
authors.lastname: Karlsson