title: Phthalates and parabens in personal care products from China: concentrations and human exposure.
abstract: Our previous studies showed that populations in China are widely exposed to phthalates and parabens. Nevertheless, sources of Chinese exposure to phthalates and parabens are not well understood. In this study, we measured concentrations of nine phthalates and six parabens in five categories of personal care products (PCPs, N = 52) collected from Tianjin, China, and estimated human exposure doses to these compounds. The most frequently detected phthalates and parabens in PCPs were diethyl phthalate (DEP) (detection frequency 54 %), methyl paraben (MeP), and n-propyl paraben (PrP) (~75 %). The concentrations of DEP in PCPs ranged from not detected (ND; <0.1 μg/g) to 937 μg/g. The highest concentrations of MeP and PrP were 2,826 and 1,564 μg/g, respectively. Median exposure dose to parabens through dermal application of PCPs in China was estimated at 18,700 μg/d, which was two orders of magnitude greater than that calculated for phthalates (45.5 μg/d). Hand and body lotions were the major contributors to exposures, and the daily exposure doses for DEP, MeP, and PrP from these products were 38.4, 10,200 and 4,890 μg, respectively.
authors.affiliation: Wadsworth Center, New York State Department of Health, and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, NY, 12201-0509, USA.
authors.forename: Ying
authors.initials: Y
authors.lastname: Guo
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Kurunthachalam
authors.initials: K
authors.lastname: Kannan
mesh_terms: D003358:Cosmetics / Q000737:chemistry*; D004781:Environmental Exposure / Q000032:analysis / Q000706:statistics & numerical data*; D015386:Hazardous Substances / Q000032:analysis*; D006801:Humans; D010226:Parabens / Q000032:analysis*; D010795:Phthalic Acids / Q000032:analysis*; D018570:Risk Assessment
chemical_list: D003358:Cosmetics; D015386:Hazardous Substances; D010226:Parabens; D010795:Phthalic Acids; C032279:phthalic acid