title: Chinese dyslexics show neural differences in morphological processing.
abstract: Previous behavioral studies have suggested that morphological awareness is impaired in Chinese children with reading disability (RD), but how this is reflected in brain alterations is not known. Using functional magnetic resonance imaging (fMRI), the current study compared morphological processing in a RD group (11-13 years old) to an age-matched typically developing (TD) group. Participants made semantic relatedness judgments to incongruent word pairs that were either semantically related but did not share a morpheme or semantically unrelated but did share a morpheme. This was compared to conditions where semantic relatedness and morphemic information was congruent. A smaller incongruency effect was found in left dorsal posterior (BA9) and ventral anterior (BA47) inferior frontal gyrus (IFG) in the RD compared to the TD, suggesting that the RD is less sensitive to morphological information. This was a specific deficit as a phonological control task that manipulated congruency between orthography and phonology did not show group differences in the IFG. Moreover, brain activation in the IFG for the incongruency effect in the semantic task was negatively correlated with reading skill for the RD group only, suggesting that higher skill children with RD may rely on a compensatory whole-word strategy by ignoring the morphemic information.
authors.affiliation: State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, PR China.
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.forename: Ran
authors.initials: R
authors.lastname: Tao
authors.forename: Wenjing
authors.initials: W
authors.lastname: Wang
authors.forename: Wenping
authors.initials: W
authors.lastname: You
authors.forename: Danling
authors.initials: D
authors.lastname: Peng
authors.forename: James R
authors.initials: JR
authors.lastname: Booth
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology* / Q000503:physiopathology*; D001931:Brain Mapping; D002648:Child; D002681:China; D004410:Dyslexia / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007600:Judgment; D008279:Magnetic Resonance Imaging; D008297:Male; D010700:Phonetics; D011932:Reading; D012660:Semantics
keywords: Chinese dyslexia; Functional magnetic resonance imaging (fMRI); Morphological processing