title: Hepatoprotective effects of mushrooms.
abstract: The particular characteristics of growth and development of mushrooms in nature result in the accumulation of a variety of secondary metabolites such as phenolic compounds, terpenes and steroids and essential cell wall components such as polysaccharides, b-glucans and proteins, several of them with biological activities. The present article outlines and discusses the available information about the protective effects of mushroom extracts against liver damage induced by exogenous compounds. Among mushrooms, Ganoderma lucidum is indubitably the most widely studied species. In this review, however, emphasis was given to studies using other mushrooms, especially those presenting efforts of attributing hepatoprotective activities to specific chemical components usually present in the mushroom extracts.
authors.affiliation: Department of Biochemistry, State University of Maringá, Maringá 87015-900, Brazil. andasoares7@gmail.com
authors.forename: Andréia Assunço
authors.initials: AA
authors.lastname: Soares
authors.forename: Anacharis Babeto
authors.initials: AB
authors.lastname: de Sá-Nakanishi
authors.forename: Adelar
authors.initials: A
authors.lastname: Bracht
authors.forename: Sandra Maria Gomes
authors.initials: SM
authors.lastname: da Costa
authors.forename: Eloá Angélica
authors.initials: EA
authors.lastname: Koehnlein
authors.forename: Cristina Giatti Marques
authors.initials: CG
authors.lastname: de Souza
authors.forename: Rosane Marina
authors.initials: RM
authors.lastname: Peralta
mesh_terms: D000363:Agaricales / Q000737:chemistry* / Q000378:metabolism; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D010636:Phenols / Q000737:chemistry / Q000494:pharmacology; D011134:Polysaccharides / Q000737:chemistry / Q000494:pharmacology; D020011:Protective Agents / Q000737:chemistry / Q000627:therapeutic use*; D011506:Proteins / Q000737:chemistry; D020940:Reishi / Q000737:chemistry / Q000378:metabolism; D013256:Steroids / Q000737:chemistry / Q000494:pharmacology; D013729:Terpenes / Q000737:chemistry / Q000494:pharmacology; D047071:beta-Glucans / Q000737:chemistry / Q000494:pharmacology
chemical_list: D010636:Phenols; D011134:Polysaccharides; D020011:Protective Agents; D011506:Proteins; D013256:Steroids; D013729:Terpenes; D047071:beta-Glucans