title: [DRESS syndrome. A clinical case report].
abstract: BACKGROUND
  DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) or reaction to drugs with eosinophilia and systemic symptoms is a serious drug reaction associated with the use of aromatic anticonvulsants and allopurinol. At least 44 drugs have been associated with DRESS. The aim was to present the case of a patient with DRESS syndrome associated with phenytoin.
  
  
  METHODS
  a 20 year old woman, with a history of seizures since childhood, presented generalised tonic-clonic seizures for the last three months. Therefore, she began treatment with 100 mg of phenytoin, administered orally, every 8 hours. Three weeks later, she developed fever up to 42 degrees, papules in the hands extending to trunk and extremities, generalized rubicund, pruritus, pain while urinating, adding hyperoxia, dysphagia and dry cough. Consequently, she went to the emergency room.
  
  
  CONCLUSIONS
  the diagnosis is clinical and it is set according to the criteria of the scale of RegiSCAR. As the initial manifestations are unspecific, the diagnosis and treatment could be delayed. The importance of recognizing this syndrome is an early treatment to get better prognostics. The mortality is up to 10 %.
authors.affiliation: Fundación Médica Sur, Hospital General de México, OD, Distrito Federal, México, Mexico. drcarlosbriones@yahoo.com.mx.
authors.forename: Jimena
authors.initials: J
authors.lastname: Muciño-Bermejo
authors.forename: Manuel
authors.initials: M
authors.lastname: Díaz de León-Ponce
authors.forename: Carlos Gabriel
authors.initials: CG
authors.lastname: Briones-Vega
authors.forename: Antonio
authors.initials: A
authors.lastname: Guerrero-Hernández
authors.forename: Oswaldo Israel
authors.initials: OI
authors.lastname: Sandoval-Ayala
authors.forename: Ana Gabriela
authors.initials: AG
authors.lastname: Sáenz-Coronado
authors.forename: Jesús Carlos
authors.initials: JC
authors.lastname: Briones-Garduño
mesh_terms: D063926:Drug Hypersensitivity Syndrome / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D055815:Young Adult
keywords: adverse effects; anticonvulsants; drug hypersensitivity, chemically induced