title: Porous metal-organic framework catalyzing the three-component coupling of sulfonyl azide, alkyne, and amine.
abstract: The robustly porous metal-organic framework MOF-Cu2I2(BTTP4) (BTTP4 = benzene-1,3,5-triyl triisonicotinate) was shown to work as an efficiently heterogeneous catalyst for the three-component coupling of sulfonyl azides, alkynes, and amines, leading to the formation of N-sulfonyl amidines in good yields. MOF-Cu2I2(BTTP4) can be recycled by simple filtration and reused at least four times without any loss in yield. Studies of the ligand effects on the three-component coupling reactions showed that BTTP4 could enhance the rate, as well as the chemoselectivity, when aromatic alkynes were employed. The catalytic process has been thoroughly studied by means of single-crystal and powder X-ray diffraction, gas and solvent adsorption, in situ (1)H NMR and FT-IR spectroscopy, X-ray photoelectron spectra (XPS), and ICP analysis of Cu leaching.
authors.affiliation: MOE Laboratory of Bioinorganic and Synthetic Chemistry/KLGHEI of Environment and Energy Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, PR China.
authors.forename: Tao
authors.initials: T
authors.lastname: Yang
authors.forename: Hao
authors.initials: H
authors.lastname: Cui
authors.forename: Changhe
authors.initials: C
authors.lastname: Zhang
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Cheng-Yong
authors.initials: CY
authors.lastname: Su