title: Surgical corner: a prospective randomized evaluation of cyanoacrylate glue devices in the closure of surgical wounds.
abstract: BACKGROUND
  The use of medical adhesives for topical wound closure is gaining in popularity over conventional wound closure materials such as sutures and staples. Adhesives provide advantages in both wound closure and patient management with good cosmetic outcome and surgeon and patient satisfaction reported.
  
  
  OBJECTIVE
  To compare the use of two currently marketed medical adhesives; LiquiBand® Flow Control and High Viscosity Dermabond ™ for the topical closure of surgical incisions.
  
  
  METHODS
  In a prospective blinded manner, subjects were randomly assigned LiquiBand® or DermabondTM for topical closure of a surgical incision. Variables compared included ease of use, time taken to close wound, subject and surgeon satisfaction with device and wound closure, cosmetic outcome at 90 days, and complication rates.
  
  
  RESULTS
  Use of both devices resulted in effective wound closure with similar high levels of cosmesis subject and surgeon satisfaction, with only minor complications reported. There was no statistically significant difference between the devices for all the parameters studied, with the exception that the Liquiband device was found to significantly reduce the amount of time required for closure.
  
  
  CONCLUSIONS
  As the two devices appear substantially equivalent in terms of key surgeon and patient variables, product cost should be the primary determinant in selection of the tissue glue device.
authors.affiliation: Beverly Hospital Oncology Care Center, Beverly, MA, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Maloney
authors.forename: Gary S
authors.initials: GS
authors.lastname: Rogers
authors.forename: Mitesh
authors.initials: M
authors.lastname: Kapadia
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003487:Cyanoacrylates / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011446:Prospective Studies; D013514:Surgical Procedures, Operative / Q000379:methods; D013997:Time Factors; D014014:Tissue Adhesives / Q000008:administration & dosage*; D058106:Wound Closure Techniques; D014945:Wound Healing
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate