title: [Structural analysis of subsidiary tar dyes contained in Food red No. 102].
abstract: Three unknown colors (A1, A2 and A3) in Food red No. 102 (R102) were identified by LC-MS and NMR analysis. Red dye A1 was azo rubine (AZO), which is not designated as a coloring agent in Japan. Red dye A2 was a structural isomer of Fast Red E (FRE), which is also not designated as a coloring agent in Japan. Red dye A3 was predicted to be an overreaction product of R102, possessing the R102 structural framework. Furthermore, AZO, which was assumed to have been produced by dimerization of a diazonium salt used as a synthetic intermediate of R102, was also identified in Food red No. 2 (R2).
authors.affiliation: Safety Science Institute, Quality Assurance Division, Suntory Business Expert Limited, Suntory Research Center, 1-1-1 Wakayamadai, Shimamoto-cho, Mishima-gun, Osaka 618-8503, Japan. Mami_Gouda@suntory.co.jp
authors.forename: Mami
authors.initials: M
authors.lastname: Goda
authors.forename: Manabu
authors.initials: M
authors.lastname: Horikawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Iwashita
authors.forename: Motomitsu
authors.initials: M
authors.lastname: Sawada
authors.forename: Daisuke
authors.initials: D
authors.lastname: Tsukazaki
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Tachibana
authors.forename: Katsumi
authors.initials: K
authors.lastname: Sugane
authors.forename: Masami
authors.initials: M
authors.lastname: Harada
mesh_terms: D001391:Azo Compounds / Q000737:chemistry* / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid; D019281:Dimerization; D005505:Food Coloring Agents / Q000737:chemistry*; D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry
chemical_list: D001391:Azo Compounds; D005505:Food Coloring Agents