title: Endovenous radiofrequency ablation and combined foam sclerotherapy treatment of multiple refluxing perforator veins in a Klippel-Trenaunay syndrome patient.
abstract: We describe an unusual pattern of venous abnormality and the use of endovenous radiofrequency ablation, using the TRans-Luminal Occlusion of Perforator technique to treat multiple refluxing perforators in a 29-year-old patient with Klippel-Trenaunay syndrome. Klippel-Trenaunay syndrome is a rare congenital anomaly characterised by a triad of features including unilateral limb overgrowth, venous varicosities and capillary malformations of the affected limb. Ultrasound findings demonstrated 22 incompetent perforator veins in the lateral aspect of the patients left leg, communicating with a complex network of large calibre varicosities causing unilateral leg oedema and pain. Staged radiofrequency ablation procedures using the Olympus Celon RFITT (radiofrequency-induced thermotherapy; please see Technical Note) device under local anaesthetic were performed. These procedures were followed with two sessions of foam sclerotherapy. This case report describes the efficacy of this treatment regime and this patient's significantly improved morbidity 18 months after initial treatment.
authors.affiliation: The Whiteley Clinic, Guildford, Surrey, UK Charmaine@thewhiteleyclinic.co.uk.
authors.forename: Cc
authors.initials: C
authors.lastname: Harrison
authors.affiliation: The Whiteley Clinic, Guildford, Surrey, UK.
authors.forename: Jm
authors.initials: J
authors.lastname: Holdstock
authors.affiliation: The Whiteley Clinic, Guildford, Surrey, UK.
authors.forename: Ba
authors.initials: B
authors.lastname: Price
authors.affiliation: The Whiteley Clinic, Guildford, Surrey, UK.
authors.forename: Ms
authors.initials: M
authors.lastname: Whiteley
mesh_terms: D000328:Adult; D000772:Anesthesia, Local; D017115:Catheter Ablation / Q000379:methods*; D057510:Endovascular Procedures / Q000379:methods*; D006801:Humans; D007715:Klippel-Trenaunay-Weber Syndrome / Q000628:therapy*; D008297:Male; D012597:Sclerosing Solutions / Q000008:administration & dosage / Q000627:therapeutic use*; D015911:Sclerotherapy / Q000379:methods*; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex; D014648:Varicose Veins / Q000000981:diagnostic imaging / Q000628:therapy*
chemical_list: D012597:Sclerosing Solutions
keywords: Klippel-Trenaunay; foam sclerotherapy; perforators; radiofrequency ablation