title: CD64 expression on monocytes in children with adenoid hypertrophy.
abstract: OBJECTIVE
  Adenoids with obstructive hypertrophy (AH) are considered to be one of the most ancient and common problems in Paediatrics. This study aimed at investigating the expression of CD 64 on monocytes in children who had to undergo adenoidectomy.
  
  
  METHODS
  Therefore, 66 children (24 females, 42 males, mean age 4.9 years), affected by AH and requiring adenoidectomy (54%) or adeno-tonsillectomy (46%) were consecutively enrolled into the study. Moreover, 30 healthy children (11 females, 19 males, mean age 11.2 years) were enrolled in this study as controls. CD64 expression on monocytes was measured.
  
  
  RESULTS
  Children with severe AH had higher CD64 values than children with AH size 3 and controls.
  
  
  CONCLUSIONS
  This preliminary study shows that CD64 expression on monocytes may be associated with severe AH, suggesting a more intense immune activation in these subjects.
authors.affiliation: Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. gio.cip@libero.it
authors.forename: Fabio
authors.initials: F
authors.lastname: Pagella
authors.forename: Mara
authors.initials: M
authors.lastname: De Amici
authors.forename: Elina
authors.initials: E
authors.lastname: Matti
authors.forename: Alessandro
authors.initials: A
authors.lastname: Pusateri
authors.forename: Marco
authors.initials: M
authors.lastname: Benazzo
authors.forename: Giorgio
authors.initials: G
authors.lastname: Ciprandi
mesh_terms: D000234:Adenoids / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005786:Gene Expression Regulation; D006801:Humans; D006984:Hypertrophy; D008297:Male; D009000:Monocytes / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D017452:Receptors, IgG / Q000096:biosynthesis* / Q000276:immunology
chemical_list: D017452:Receptors, IgG