title: Prognostic value of elevated mean platelet volume in patients undergoing primary angioplasty for ST-elevation myocardial infarction.
abstract: OBJECTIVE
  The aim of this study was to evaluate the prognostic value of mean platelet volume (MPV) in patients with STEMI undergoing primary percutaneous coronary intervention (PCI).
  
  
  METHODS
  We prospectively enrolled 495 consecutive STEMI patients.The study population was divided into tertiles based on admission MPV values. The high MPV group (n= 148) was defined as a value in the third tertile (> 8.9), and the low MPV group (n = 347) included those patients with a value in the lower two tertiles (< or = 8.9). Clinical characteristics, in-hospital and six-month outcomes of primary PCI were analysed.
  
  
  RESULTS
  Higher six-month all-cause mortality rates were observed in the high MPV group In Cox multivariate analysis; a high admission MPV value (> 8.9) was found to be a powerful independent predictor of six-month all-cause mortality.
  
  
  CONCLUSIONS
  These results suggest that a high admission MPV level was associated with increased six-month all-cause mortality in patients with STEMI undergoing primary PCI.
authors.affiliation: Dept. of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Istanbul, Turkey. droakgul@yahoo.com
authors.forename: Ozgur
authors.initials: O
authors.lastname: Akgul
authors.forename: Huseyin
authors.initials: H
authors.lastname: Uyarel
authors.forename: Hamdi
authors.initials: H
authors.lastname: Pusuroglu
authors.forename: Mehmet
authors.initials: M
authors.lastname: Gul
authors.forename: Nilgun
authors.initials: N
authors.lastname: Isiksacan
authors.forename: Selahattin
authors.initials: S
authors.lastname: Turen
authors.forename: Mehmet
authors.initials: M
authors.lastname: Erturk
authors.forename: Ozgur
authors.initials: O
authors.lastname: Surgit
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cetin
authors.forename: Umit
authors.initials: U
authors.lastname: Bulut
authors.forename: Omer Faruk
authors.initials: OF
authors.lastname: Baycan
authors.forename: Nevzat
authors.initials: N
authors.lastname: Uslu
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D001792:Blood Platelets / Q000166:cytology / Q000502:physiology*; D002423:Cause of Death / Q000639:trends; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000401:mortality / Q000601:surgery; D010976:Platelet Count; D057234:Preoperative Period; D011379:Prognosis; D011446:Prospective Studies; D012720:Severity of Illness Index; D013997:Time Factors; D014421:Turkey / Q000453:epidemiology