title: Photochirogenesis with mutant human serum albumins: enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylate.
abstract: Mutant human serum albumins accelerated the photocyclodimerization of 2-anthracenecarboxylate to afford chiral cyclodimers in 75-85% enantiomeric excesses, revealing that the mutations to impair non-productive sites 1 and/or 2 enhanced the substrate binding to site 3 without seriously damaging its inherently high photochirogenic ability.
authors.affiliation: Office for University-Industry Collaboration, Osaka University, Yamada-oka, Suita, 565-0871, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Nishijima
authors.forename: Hanako
authors.initials: H
authors.lastname: Kato
authors.forename: Gaku
authors.initials: G
authors.lastname: Fukuhara
authors.forename: Cheng
authors.initials: C
authors.lastname: Yang
authors.forename: Tadashi
authors.initials: T
authors.lastname: Mori
authors.forename: Toru
authors.initials: T
authors.lastname: Maruyama
authors.forename: Masaki
authors.initials: M
authors.lastname: Otagiri
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Inoue
mesh_terms: D000873:Anthracenes / Q000737:chemistry / Q000378:metabolism*; D001665:Binding Sites; D002264:Carboxylic Acids / Q000737:chemistry / Q000378:metabolism*; D003500:Cyclization; D019281:Dimerization; D006801:Humans; D009154:Mutation; D055668:Photochemical Processes; D012709:Serum Albumin / Q000235:genetics* / Q000378:metabolism*; D013237:Stereoisomerism
chemical_list: C476641:2-anthracenecarboxylate; D000873:Anthracenes; D002264:Carboxylic Acids; D012709:Serum Albumin