title: [Significance of No.14v lymph node dissection for advanced gastric cancer undergoing D2 lymphadenectomy].
abstract: OBJECTIVE
  To elucidate the necessity of No.14v lymph node dissection in D2 lymphadenectomy for advanced gastric cancer.
  
  
  METHODS
  Clinicopathological data of 131 cases of advanced gastric cancer receiving D2 or D2+ plus No.14v lymph node dissection were reviewed retrospectively. Clinicopathological factors associated with No.14v lymph node metastasis were analyzed and prognostic value of No.14v lymph node metastasis was evaluated.
  
  
  RESULTS
  Of the 131 patients, 24 (18.3%) had positive No.14v lymph node. The incidence of 14v metastasis was associated with tumor location, tumor size, depth of invasion, N staging, TNM staging, No.1, No.6, and No.8a lymph nodes metastasis. Tumor location and N staging were independent risk factors for No.14v metastasis (all P<0.05). The 5-year survival rate was 8.3% and 37.8% in patients with and without No.14v metastasis respectively. The difference was statistically significant (P<0.01). Multivariate analysis revealed that metastasis of No.14v was an independent prognostic factor for advanced gastric cancer after D2 lymphadenectomy (P=0.029, RR=1.807, 95%CI:1.064-3.070).
  
  
  CONCLUSIONS
  For advanced middle and lower gastric cancers, especially those with larger size, serosa invasion and possibility of No.6 lymph node metastasis, it is necessary and feasible to remove the No.14v lymph node.
authors.affiliation: Department of Gastric Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
authors.forename: Yue-xiang
authors.initials: YX
authors.lastname: Liang
authors.forename: Han
authors.initials: H
authors.lastname: Liang
authors.forename: Xue-wei
authors.initials: XW
authors.lastname: Ding
authors.forename: Xiao-na
authors.initials: XN
authors.lastname: Wang
authors.forename: Liang-liang
authors.initials: LL
authors.lastname: Wu
authors.forename: Hong-gen
authors.initials: HG
authors.lastname: Liu
authors.forename: Xu-guang
authors.initials: XG
authors.lastname: Jiao
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000601:surgery*