title: Observation of the long-term effects of lifestyle intervention during balneotherapy in metabolic syndrome.
abstract: OBJECTIVE
  Estimate the effect of lifestyle adjustment activities in patients with metabolic syndrome treated by prescribed balneotherapy.
  
  
  METHODS
  Observational pilot cohort study with 12-month follow-up after multidimensional lifestyle training (physical, dietary, educational) during 3-week standard stay in the spa town of Eugénie-les-Bains.
  
  
  RESULTS
  Of 145 eligible patients, 97 were included; 63 were followed and analysable. At inclusion all had ≥3 National cholesterol education program-Adult treatment panel III (NCEP-ATPIII) criteria defining metabolic syndrome, 76.2% were female, mean age was 61.2 years. At the end of follow-up (median:10.4 months, Inter-Quartile Range: [6.7;11.4]), 48 of these 63 patients (76.2%) no longer had metabolic syndrome (95%CI [65.7;86.7]). These 48 patients without metabolic syndrome at the end of follow-up represented 49.5% of the 97 included (95%CI [39.5;59.4]).
  
  
  CONCLUSIONS
  Future studies of lifestyle interventions taking advantage of the spa environment can be expected to find least one third of patients free of metabolic syndrome at the end of 12-month follow-up in the intervention group.
authors.affiliation: Université de Bordeaux, Bordeaux, France.
authors.forename: Henri
authors.initials: H
authors.lastname: Gin
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Demeaux
authors.forename: Angela
authors.initials: A
authors.lastname: Grelaud
authors.forename: Adeline
authors.initials: A
authors.lastname: Grolleau
authors.forename: Cécile
authors.initials: C
authors.lastname: Droz-Perroteau
authors.forename: Philip
authors.initials: P
authors.lastname: Robinson
authors.forename: Régis
authors.initials: R
authors.lastname: Lassalle
authors.forename: Abdelilah
authors.initials: A
authors.lastname: Abouelfath
authors.forename: Michel
authors.initials: M
authors.lastname: Boisseau
authors.forename: Christian
authors.initials: C
authors.lastname: Toussaint
authors.forename: Nicholas
authors.initials: N
authors.lastname: Moore
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry; D001452:Balneology; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D003131:Combined Modality Therapy; D004038:Diet, Reducing; D005081:Exercise Therapy; D005260:Female; D005500:Follow-Up Studies; D006294:Health Resorts; D006801:Humans; D008019:Life Style; D008055:Lipids / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000178:diet therapy / Q000628:therapy*; D008875:Middle Aged; D009042:Motivation; D010353:Patient Education as Topic; D010865:Pilot Projects; D011446:Prospective Studies; D016896:Treatment Outcome; D015431:Weight Loss
chemical_list: D001786:Blood Glucose; D008055:Lipids