title: Influence of the toothpaste with brazilian ethanol extract propolis on the oral cavity health.
abstract: Propolis-based therapeutic agents represent this potential for the development of new drugs in dental care. The aim of a clinical-cohort study was to determine the influence of application of toothpaste enriched with Brazilian extract of propolis (EEP) on health status of oral cavity. Laboratory analysis was conducted in order to assess the chemical composition of EEP including total phenolic compounds, the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity, ABTS radical cation scavenging activity, and FRAP assay. Clinical research involved two groups of subjects comprising 32 adult patients, with assessment based on the preliminary evaluation of the state of their marginal periodontium. The investigation of oral health indices API, OHI, and SBI and microbiological examination of oral microflora were also carried out. Results obtained indicated time-dependent microbial action of EEP at 50 mg/L concentration, with antimicrobial activity against Gram-positive bacteria. The total decrease of API, OHI, and SBI mean values was observed. Hygienic preparations with 3% content of Brazilian ethanol extract of green propolis (EEP) efficiently support removal of dental plaque and improve the state of marginal periodontium.
authors.affiliation: Department of Conservative Dentistry with Endodontics, Faculty of Medicine and Dentistry, Medical University of Silesia in Katowice, Plac Akademicki 17, 41902 Bytom, Poland.
authors.forename: Dariusz
authors.initials: D
authors.lastname: Skaba
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Morawiec
authors.forename: Marta
authors.initials: M
authors.lastname: Tanasiewicz
authors.forename: Anna
authors.initials: A
authors.lastname: Mertas
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Bobela
authors.forename: Ewelina
authors.initials: E
authors.lastname: Szliszka
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Skucha-Nowak
authors.forename: Monika
authors.initials: M
authors.lastname: Dawiec
authors.forename: Rindai
authors.initials: R
authors.lastname: Yamamoto
authors.forename: Shinobu
authors.initials: S
authors.lastname: Ishiai
authors.forename: Yuki
authors.initials: Y
authors.lastname: Makita
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Redzynia
authors.forename: Beata
authors.initials: B
authors.lastname: Janoszka
authors.forename: Iwona
authors.initials: I
authors.lastname: Niedzielska
authors.forename: Wojciech
authors.initials: W
authors.lastname: Król