title: Trick to treat: tricking the thymus to treat cancer.
abstract: In this issue of Blood, Schmitt et al address the biology and safety of T cells engineered to express T-cell receptor (TCR) variants endowed with enhanced affinity for tumor-associated antigens.
authors.affiliation: San Raffaele Scientific Institute.
authors.forename: Chiara
authors.initials: C
authors.lastname: Bonini
authors.forename: Anna
authors.initials: A
authors.lastname: Mondino
mesh_terms: D000818:Animals; D000951:Antigens, Neoplasm / Q000276:immunology*; D001324:Autoantigens / Q000276:immunology*; D015316:Genetic Therapy; D006801:Humans; D011948:Receptors, Antigen, T-Cell / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology*
chemical_list: D000951:Antigens, Neoplasm; D001324:Autoantigens; D011948:Receptors, Antigen, T-Cell