title: Percutaneous edge-to-edge mitral valve repair. Current clinical evidence with the MitraClip System.
abstract: In the past few years, a myriad of technologies have been developed for percutaneous repair of the mitral valve for patients with severe mitral regurgitation (MR) and at high risk for traditional open-heart mitral valve surgery. Among them, MitraClip has emerged as the only clinically safe and effective method for percutaneous mitral valve repair. This device mimics the surgical edge-to-edge mitral valve repair initially described by Dr. Alfieri. In this article, we review the current clinical evidence on the use of the MitraClip--from the randomized control trial EVEREST II to the information derived from expert high-volume centers.
authors.affiliation: Department of Cardiology, Rigshospitalet Copenhagen, Blegdamsvej 9, Copenhagen, Denmark.
authors.forename: R
authors.initials: R
authors.lastname: Estevez-Loureiro
authors.forename: O
authors.initials: O
authors.lastname: Franzen
mesh_terms: D019317:Evidence-Based Medicine; D006801:Humans; D058386:Mitral Valve Annuloplasty / Q000295:instrumentation* / Q000706:statistics & numerical data*; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery*; D015995:Prevalence; D011474:Prosthesis Design; D015641:Radiography, Interventional / Q000706:statistics & numerical data*; D013525:Surgical Instruments / Q000706:statistics & numerical data*; D016896:Treatment Outcome