title: A radiologist's guide to treatment response criteria in oncologic imaging: anatomic imaging biomarkers.
abstract: OBJECTIVE
  The purpose of this article is to describe the imaging biomarkers of treatment response and provide an overview of anatomic imaging biomarkers.
  
  
  CONCLUSIONS
  Imaging biomarkers of treatment response have evolved into the primary endpoint of response in most phase 2 studies. Anatomic imaging biomarkers are applied to depict change in tumor size in response to treatment and are currently the most commonly applied method of treatment response evaluation.
authors.affiliation: Department of Radiology, John H. Stroger Jr. Hospital, 1901 W Harrison St, Chicago, IL 60612, USA. pedramrezai@hotmail.com
authors.forename: Pedram
authors.initials: P
authors.lastname: Rezai
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Pisaneschi
authors.forename: Chun
authors.initials: C
authors.lastname: Feng
authors.forename: Vahid
authors.initials: V
authors.lastname: Yaghmai
mesh_terms: D014408:Biomarkers, Tumor; D003952:Diagnostic Imaging; D017408:Guidelines as Topic; D006801:Humans; D009369:Neoplasms / Q000473:pathology* / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor