title: Hypertriglyceridemic waist and newly-diagnosed diabetes among remote-dwelling Indigenous Australians.
abstract: OBJECTIVE
  Hypertriglyceridemic waist (HTgW) is predictive of cardiovascular disease. The HTgW relationship with diabetes is little studied.
  
  
  METHODS
  This study analysed data from diabetes and cardiovascular risk factor screening programmes in remote Indigenous Australian settlements. Elevated waist girth (EW) was defined as ≥90 cm for men (n = 1134) or ≥80 cm for women (n = 1313). Hypertriglyceridemia (ETg) was defined as ≥1.7 mmol/L. Diabetes was defined as fasting plasma glucose ≥7.0 mmol/L. Body mass index (BMI) was categorised as <22, 22-24.9 and >25.0 kg/m(2). Logistic regression was used to analyse the odds of newly-diagnosed diabetes for individuals with either HTgW, ETg or EW, relative to individuals with values below cut-offs.
  
  
  RESULTS
  The prevalence of HTgW was 33.2% for men and 34.8% for women. Accounting for age-group and gender, newly-diagnosed diabetes was associated (odds ratio (OR) (95% confidence interval)) with HTgW: 9.6 (6.6, 13.8). The relationship remained strong after accounting for the covariates BMI and smoking (OR = 4.9 (2.7, 8.8)). In BMI-stratified analyses the strongest odds were observed for the lowest category (<22 kg/m(2): OR = 12.9 (4.0, 41.7)).
  
  
  CONCLUSIONS
  HTgW has a high prevalence and is associated with newly-diagnosed diabetes in Indigenous people, particularly those with BMI <22 kg/m(2), whom clinicians might not normally consider for screening.
authors.affiliation: School of Population Health, University of South Australia , Australia .
authors.forename: M
authors.initials: M
authors.lastname: Daniel
authors.forename: C
authors.initials: C
authors.lastname: Paquet
authors.forename: S J
authors.initials: SJ
authors.lastname: Kelly
authors.forename: G
authors.initials: G
authors.lastname: Zang
authors.forename: K G
authors.initials: KG
authors.lastname: Rowley
authors.forename: R
authors.initials: R
authors.lastname: McDermott
authors.forename: K
authors.initials: K
authors.lastname: O'Dea
mesh_terms: D000293:Adolescent; D000328:Adult; D001315:Australia / Q000453:epidemiology; D001827:Body Height; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000453:epidemiology / Q000208:ethnology*; D006801:Humans; D064250:Hypertriglyceridemic Waist / Q000150:complications / Q000453:epidemiology / Q000208:ethnology*; D008875:Middle Aged; D015995:Prevalence; D055105:Waist Circumference; D055815:Young Adult