title: C-H alkenylation of azoles with enols and esters by nickel catalysis.
abstract: Rather u(Ni)que: Two new C-H alkenylation reactions, that is C-H/C-O alkenylation and decarbonylative C-H alkenylation, of azoles are uniquely catalyzed by Ni/dcype. These azole alkenylation reactions are successfully applied to the convergent formal synthesis of siphonazole B.
authors.affiliation: Department of Chemistry, Graduate School of Science, Nagoya University, Chikusa, Nagoya 464-8602 (Japan); College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei, 430072 (P.R. China).
authors.forename: Lingkui
authors.initials: L
authors.lastname: Meng
authors.forename: Yuko
authors.initials: Y
authors.lastname: Kamada
authors.forename: Kei
authors.initials: K
authors.lastname: Muto
authors.forename: Junichiro
authors.initials: J
authors.lastname: Yamaguchi
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Itami
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis*; D001393:Azoles / Q000737:chemistry*; D001688:Biological Products; D002384:Catalysis; D004952:Esters / Q000737:chemistry*; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*
chemical_list: D000475:Alkenes; D001393:Azoles; D001688:Biological Products; D004952:Esters; D009532:Nickel
keywords: CH activation; alkenes; heterocycles; natural products; nickel