title: [Molecular components of JAK/STAT signaling pathway and its connection with transcription machinery].
abstract: JAK/STAT is one of the conservative signaling pathways in higher eukaryotes which plays a critical role in different ontogenesis processes. This article gives a review of the pathway structure at the molecular level, mainly in a model organism Drosophila. There are data about relationship of the signaling pathway and transcription machinery of higher eukaryotes.
authors.forename: A V
authors.initials: AV
authors.lastname: Shaposhnikov
authors.forename: I F
authors.initials: IF
authors.lastname: Komar'kov
authors.forename: L A
authors.initials: LA
authors.lastname: Lebedeva
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Shidlovskiĭ
mesh_terms: D000818:Animals; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D004331:Drosophila melanogaster; D006801:Humans; D053612:Janus Kinases / Q000235:genetics / Q000378:metabolism*; D050791:STAT Transcription Factors / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic / Q000502:physiology*
chemical_list: D029721:Drosophila Proteins; D050791:STAT Transcription Factors; D014157:Transcription Factors; D053612:Janus Kinases; C085845:hop protein, Drosophila