title: Asymptomatic hyper-creatine-kinase-emia as sole manifestation of inclusion body myositis.
abstract: Sporadic inclusion body myositis (sIBM) usually manifests with painless weakness of the hand, finger and hip flexors. Absence of symptoms or signs, but mild hyper-CK-emia as the sole manifestation of IBM, has not been reported. We report the case of a 73-year-old male who presented with asymptomatic recurrent hyper-CK-emia ranging from 200 to 1324U/L (n<171U/L), since 10 years. Clinical neurologic investigation, nerve conduction studies and EMG were non-informative. Muscle biopsy surprisingly revealed sIBM. sIBM may be asymptomatic and may manifest with hyper-CK-emia exclusively. So, it has to be included in the differential diagnoses of asymptomatic hyper-CK-emia.
authors.affiliation: Krankenanstalt Rudolfstiftung.
authors.forename: Josef
authors.initials: J
authors.lastname: Finsterer
authors.forename: Claudia
authors.initials: C
authors.lastname: Stöllberger
authors.forename: Gabor G
authors.initials: GG
authors.lastname: Kovacs
keywords: cardiomyopathy; creatine-kinase; muscle biopsy; myositis; neuromuscular disorder