title: Genetic characterization and emergence of the metallo-β-lactamase GIM-1 in Pseudomonas spp. and Enterobacteriaceae during a long-term outbreak.
abstract: Since the first isolation in 2002, the metallo-β-lactamase GIM-1 has not been detected outside Germany. The data presented here, for 50 clinical blaGIM-1-positive isolates, including Pseudomonas spp. and Enterobacteriaceae (Enterobacter cloacae, Klebsiella oxytoca, Serratia marcescens, Escherichia coli, and Citrobacter freundii), collected between 2007 and 2012 at the original site in an ongoing outbreak, demonstrate a diverse genetic background and dissemination of the gene conferring resistance to enteric bacteria.
authors.affiliation: Institute of Medical Microbiology and Hospital Hygiene, University Hospital, Heinrich-Heine-University, Düsseldorf, Germany.
authors.forename: Andreas F
authors.initials: AF
authors.lastname: Wendel
authors.forename: Alexander H B
authors.initials: AH
authors.lastname: Brodner
authors.forename: Stephan
authors.initials: S
authors.lastname: Wydra
authors.forename: Sofija
authors.initials: S
authors.lastname: Ressina
authors.forename: Birgit
authors.initials: B
authors.lastname: Henrich
authors.forename: Klaus
authors.initials: K
authors.lastname: Pfeffer
authors.forename: Mark A
authors.initials: MA
authors.lastname: Toleman
authors.forename: Colin R
authors.initials: CR
authors.lastname: Mackenzie
mesh_terms: D004755:Enterobacteriaceae / Q000201:enzymology* / Q000235:genetics*; D032023:Integrons / Q000235:genetics; D008969:Molecular Sequence Data; D011549:Pseudomonas / Q000201:enzymology* / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D001618:beta-Lactamases