title: Isolation of a 2-hydroxytetrahydrofuran complex from copper-promoted hydroxylation of THF.
abstract: A complex of a binucleating macrocyclic ligand comprising a [Cu(II)(μ-OH)Na](2+) core reacts with CuI in THF/CH3CN to yield a novel species with a deprotonated 2-hydroxytetrahydrofuran (THF-2-ol) bridging between Cu(II) and Na(I) ions. The complexes were characterized by X-ray crystallography, electron paramagnetic resonance spectroscopy, and electrospray ionization mass spectrometry. (18)O-labeling studies support incorporation of the O atom from μ-OH into the coordinated THF-2-ol ligand.
authors.affiliation: Department of Chemistry and Center for Metals in Biocatalysis, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455, United States.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Halvagar
authors.forename: William B
authors.initials: WB
authors.lastname: Tolman
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D005663:Furans / Q000737:chemistry*; D006900:Hydroxylation; D008958:Models, Molecular; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D005663:Furans; D009942:Organometallic Compounds; C018674:tetrahydrofuran; D003300:Copper