title: Morphological and functional outcome after brilliant blue G-assisted macular hole surgery.
abstract: OBJECTIVE
  To investigate the outcome of brilliant blue G (BBG)-assisted internal limiting membrane peeling in macular hole surgery after a follow-up of 6 months.
  
  
  METHODS
  In this retrospective study 20 eyes have been treated with BBG-assisted macular hole surgery. After a follow-up of 6 months, the functional and anatomical outcomes have been analyzed.
  
  
  RESULTS
  The mean preoperative best-corrected visual acuity (BCVA) was 0.7 logMAR units (mean ± SD 0.66 ± 0.27). After 3 months, the mean BCVA increased not significantly to 0.4 (0.54 ± 0.30), but a significant improvement to 0.2 logMAR units (0.28 ± 0.23) could be detected after 6 months compared to baseline (p < 0.01). Primary macular hole closure after a single surgery was found in 17 of 20 eyes.
  
  
  CONCLUSIONS
  BBG exhibits sufficient staining qualities and safety profile leading to a significant functional improvement after successful macular hole surgery.
authors.affiliation: University Eye Hospital, University of Lübeck, Lübeck, Germany.
authors.forename: Julia
authors.initials: J
authors.lastname: Lüke
authors.forename: Inger
authors.initials: I
authors.lastname: Lüdeke
authors.forename: Alina
authors.initials: A
authors.lastname: Acksteiner
authors.forename: Khaled
authors.initials: K
authors.lastname: Nassar
authors.forename: Hans
authors.initials: H
authors.lastname: Hoerauf
authors.forename: Salvatore
authors.initials: S
authors.lastname: Grisanti
authors.forename: Matthias
authors.initials: M
authors.lastname: Lüke
mesh_terms: D000328:Adult; D000368:Aged; D001485:Basement Membrane / Q000473:pathology / Q000601:surgery*; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012167:Retinal Perforations / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D012394:Rosaniline Dyes; D013194:Staining and Labeling / Q000379:methods; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology
chemical_list: D004396:Coloring Agents; D012394:Rosaniline Dyes; C004692:coomassie Brilliant Blue