title: Massive bone marrow involvement in an end stage renal failure case with erythropoietin-resistant anemia and primary hyperoxaluria.
abstract: Primary hyperoxaluria is a rare autosomal recessive disorder. Type 1 PH is the most common form and develops due to a defect in a liver specific enzyme the alanine aminotransferase enzyme. As a result of the enzyme deficiency, there is an overproduction of oxalate and excessive urinary excretion. Recurrent urolithiasis and nephrocalcinosis are the most important findings of the disorder and often at the beginning end-stage renal disease develops. This report presents a case backed up by literature of a patient with end stage renal failure and erythropoietin-resistant anaemia whose bone marrow biopsy showed crystal deposition which received delayed diagnosis of oxalosis.
authors.affiliation: Department of Pathology, Bozyaka Training and Research Hospital, Izmir, Turkey. fundadr@gmail.com
authors.forename: Funda
authors.initials: F
authors.lastname: Taşlı
authors.forename: Güliz
authors.initials: G
authors.lastname: Özkök
authors.forename: Ebru Sevinç
authors.initials: ES
authors.lastname: Ok
authors.forename: Nur
authors.initials: N
authors.lastname: Soyer
authors.forename: Hülya
authors.initials: H
authors.lastname: Mollamehmetoğlu
authors.forename: Enver
authors.initials: E
authors.lastname: Vardar
mesh_terms: D000328:Adult; D000740:Anemia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D001853:Bone Marrow / Q000473:pathology*; D004921:Erythropoietin / Q000627:therapeutic use*; D006801:Humans; D006959:Hyperoxaluria / Q000175:diagnosis / Q000209:etiology*; D006960:Hyperoxaluria, Primary / Q000150:complications / Q000175:diagnosis*; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000209:etiology*; D008297:Male
chemical_list: D004921:Erythropoietin