title: Results of a preoperative autologous blood donation program for patients undergoing elective major spine surgery.
abstract: OBJECTIVE
  Spinal surgery has been shown to have a high blood transfusion requirement. Preoperative autologous blood donation (PABD) is a strategy to reduce the allogeneic transfusions in this subset of patients.
  
  
  METHODS
  We retrospectively reviewed transfusion outcome of patients undergoing elective major spinal surgery from 2005 to 2011, and included in the PABD program. Transfusion outcome was compared with a group of patients that did not enter in the program during the same period.
  
  
  RESULTS
  A total of 148 patients were included in the program during the analyzed period. Patients in the PABD program benefited from reduced exposure to allogeneic blood (Odds Ratio: 0.077, 95% confidence interval 0.043-0.140). However, 12.16% (n=18) of these patients received also allogeneic blood (total 40 red blood cell units). Univariate analysis showed the following parameters as significantly predictors of transfusion: inclusion in the program (p<0.000), number of levels fused (Odds Ratio: 1.143, p=0.010), and number of autologous red blood cells donated (Odds Ratio: 1.906, p<0.000).
  
  
  CONCLUSIONS
  The preoperative autologous blood donation program designed in our hospital was effective for reducing allogeneic transfusion in mostly young patients under major elective spinal surgery. However and as expected, their inclusion in the program increased the risk to be transfused.
authors.affiliation: Blood Bank, Hematology Department, Hospital Universitari I Politècnic La Fe, Valencia 46026, Spain. Electronic address: solves_pil@gva.es.
authors.forename: Pilar
authors.initials: P
authors.lastname: Solves
authors.forename: Nelly
authors.initials: N
authors.lastname: Carpio
authors.forename: Federico
authors.initials: F
authors.lastname: Moscardo
authors.forename: Teresa
authors.initials: T
authors.lastname: Bas
authors.forename: Carolina
authors.initials: C
authors.lastname: Cañigral
authors.forename: Claudia
authors.initials: C
authors.lastname: Salazar
authors.forename: Blanca
authors.initials: B
authors.lastname: Boluda
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: Sanz
mesh_terms: D000293:Adolescent; D000328:Adult; D001782:Blood Donors; D001804:Blood Transfusion, Autologous; D002648:Child; D017558:Elective Surgical Procedures; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D012189:Retrospective Studies; D013131:Spine / Q000601:surgery*
keywords: Allogeneic transfusion; Autologous transfusion; Preoperative blood collection; Spinal surgery; Transfusion outcome