title: Ovulation and rate of implantation following unilateral ovariectomy in mice.
abstract: OBJECTIVE
  Removal of an ovary of any side of the body is called the unilateral ovariectomy (ULO). ULO models are used to analyze the existence of functional and physiological asymmetries between the ovaries, including the ovum implantation.
  
  
  METHODS
  ULO was done in mice without any specification on their stages of the estrous cycle. The animals were mated between 3(rd) and 15(th) day after ULO to observe the consequence of ULO on ovulation and ovum implantation.
  
  
  RESULTS
  Ovulation and number of implantation were decreased in proportion to single contralateral ovary if the animals were mated within 36 hrs of ULO. It resulted in increased weight of contralateral ovary due to hypertrophy, and also in compensatory ovulation, formation of corpus luteum (CL) that reached a peak after 14(th) and 15(th) day of ULO (sacrificed on 5(th) day of pregnancy i.e., 19(th) and 20(th) day of ULO) compared to animals undergone sham-surgery. Numbers of implantations were also increased progressively on the contralateral ovarian side and get to a peak after similar days of compensation.
  
  
  CONCLUSIONS
  Following ULO, the remaining ovary started to compensate within 5(th) to 6(th) day of ULO even during pregnancy. Ovarian histology also showed increased formation of CL which is a marker of rate of ovulation.
authors.affiliation: Department of Physiology, Vidyasagar College for Women, University of Calcutta, Kolkata, India.
authors.forename: Koushik
authors.initials: K
authors.lastname: Bhattacharya
keywords: Corpus luteum; follicle stimulating hormone; implantation; ovariectomy; ovulation