title: The physiological and pathophysiological roles of adipocyte miRNAs.
abstract: MicroRNAs (miRNAs) are highly conserved, small, noncoding RNAs that regulate gene expression at the posttranscriptional level. Their actions affect numerous important biological processes, including adipocyte differentiation and function, sugar and lipid metabolism, and insulin production and secretion. Recent reports suggest miRNAs may also be involved in the pathogenic processes of obesity, diabetes, and insulin resistance. In this review, we summarize research progresses on adipocyte miRNAs and their physiological and pathological implications.
authors.affiliation: Department of Physiology, School of Medicine, University of South China, Hengyang, PR China.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Ling
authors.forename: Xing
authors.initials: X
authors.lastname: Li
authors.forename: Chao Hua
authors.initials: CH
authors.lastname: Yao
authors.forename: Bi
authors.initials: B
authors.lastname: Hu
authors.forename: Duanfang
authors.initials: D
authors.lastname: Liao
authors.forename: Shuidong
authors.initials: S
authors.lastname: Feng
authors.forename: Gebo
authors.initials: G
authors.lastname: Wen
authors.forename: Liang
authors.initials: L
authors.lastname: Zhang
mesh_terms: D041721:3T3-L1 Cells; D017667:Adipocytes / Q000166:cytology*; D050156:Adipogenesis; D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D002454:Cell Differentiation; D003920:Diabetes Mellitus / Q000378:metabolism; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007333:Insulin Resistance; D050356:Lipid Metabolism; D051379:Mice; D035683:MicroRNAs / Q000378:metabolism*; D009765:Obesity / Q000378:metabolism
chemical_list: D035683:MicroRNAs; D005947:Glucose