title: [A patient with primary breast cancer who responded remarkably well to neoadjuvant chemotherapy with FEC100 followed by Abraxane].
abstract: A 49-year-old woman visited our hospital presentind with a right breast lump. She underwent core needle biopsy, and her disease was diagnosed as breast cancer(invasive ductal carcinoma, ER slightly positive, PgR and HER2 negative). We chose neoadjuvant chemotherapy because the tumor size was over 3 cm in diameter with a histological grade III, and she asked to have her breast conserved. Because she had an allergy to alcohol, we treated her with FEC100 followed by Abraxane(260mg/ m2)q3W for 4 courses. After chemotherapy, she received breast conserving therapy. During the treatment with Abraxane, the patient was very well and showed no major side effects except for grade 3 neutropenia was found on an outpatient basis. After chemotherapy, breast MRI detected no invasive lesion. Pathological examination showed pCR. We concluded that Abraxane was a good option as neoadjuvant chemotherapy for early breast cancer.
authors.affiliation: Dept. of Breast Surgery, Japanease Red Cross Society of Wakayama Medical Center, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yoshibayashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishiguro
authors.forename: Kanako
authors.initials: K
authors.lastname: Kawaguchi
authors.forename: Mako
authors.initials: M
authors.lastname: Yamoto
authors.forename: Tomomi
authors.initials: T
authors.lastname: Nishimura
authors.forename: Harumi
authors.initials: H
authors.lastname: Yamada
authors.forename: Maki
authors.initials: M
authors.lastname: Namura
authors.forename: Naoko
authors.initials: N
authors.lastname: Nishio
authors.forename: Kyouhei
authors.initials: K
authors.lastname: Nakamura
authors.forename: Koutarou
authors.initials: K
authors.lastname: Shimada
authors.forename: Kazuo
authors.initials: K
authors.lastname: Ono
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kato
mesh_terms: D000068196:Albumin-Bound Paclitaxel; D000418:Albumins / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D017239:Paclitaxel / Q000008:administration & dosage
chemical_list: D000068196:Albumin-Bound Paclitaxel; D000418:Albumins; D017239:Paclitaxel