title: MisPred: a resource for identification of erroneous protein sequences in public databases.
abstract: Correct prediction of the structure of protein-coding genes of higher eukaryotes is still a difficult task; therefore, public databases are heavily contaminated with mispredicted sequences. The high rate of misprediction has serious consequences because it significantly affects the conclusions that may be drawn from genome-scale sequence analyses of eukaryotic genomes. Here we present the MisPred database and computational pipeline that provide efficient means for the identification of erroneous sequences in public databases. The MisPred database contains a collection of abnormal, incomplete and mispredicted protein sequences from 19 metazoan species identified as erroneous by MisPred quality control tools in the UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, NCBI/RefSeq and EnsEMBL databases. Major releases of the database are automatically generated and updated regularly. The database (http://www.mispred.com) is easily accessible through a simple web interface coupled to a powerful query engine and a standard web service. The content is completely or partially downloadable in a variety of formats. DATABASE URL: http://www.mispred.com.
authors.affiliation: Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, H-1113 Budapest, Hungary.
authors.forename: Alinda
authors.initials: A
authors.lastname: Nagy
authors.forename: László
authors.initials: L
authors.lastname: Patthy
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D030562:Databases, Protein; D020407:Internet; D058977:Molecular Sequence Annotation; D008969:Molecular Sequence Data; D011506:Proteins / Q000737:chemistry*; D020539:Sequence Analysis, Protein; D014584:User-Computer Interface; D014981:Xenopus
chemical_list: D011506:Proteins