title: [Opiate substitution treatment's cycles in a five-year followed-up cohort in ambulatory practice].
abstract: OBJECTIVE
  To describe opiate substitution treatment (OST) cycles in a five year followed-up cohort of patients initiating OST during 5 years in ambulatory practice.
  
  
  METHODS
  Data were extracted from Health Insurance System Database from January 1(st) 2005 to December 31(st) 2010 for "Haute Garonne" (South Western France area, 1 million inhabitants). Patients starting OST were included. Drop-outs were identified throughout the follow-up.
  
  
  RESULTS
  Five hundred patients were included, 72% of men, median age of 33 years. Median number of OST cycles was 2 [1; 3] on 5 years. Median duration of first OST cycle was 214 [77; 689] days. Median delay between first and second OST cycle was 80 [23; 241] days. Retention rate at one year was 38.2%.
  
  
  CONCLUSIONS
  More than 50% of patients had at least 2 cycles of OST.
authors.affiliation: Département universitaire de Médecine générale, Faculté de Médecine, Toulouse, France. julie.dupouy@univ-tlse3.fr
authors.forename: Julie
authors.initials: J
authors.lastname: Dupouy
authors.forename: Jacques
authors.initials: J
authors.lastname: Bez
authors.forename: Jacques
authors.initials: J
authors.lastname: Barsony
authors.forename: Stéphane
authors.initials: S
authors.lastname: Oustric
authors.forename: Maryse
authors.initials: M
authors.lastname: Lapeyre-Mestre
mesh_terms: D000328:Adult; D000553:Ambulatory Care / Q000706:statistics & numerical data*; D002047:Buprenorphine / Q000008:administration & dosage / Q000627:therapeutic use*; D015897:Comorbidity; D003695:Delivery of Health Care; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D005602:France; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008691:Methadone / Q000008:administration & dosage / Q000627:therapeutic use*; D058850:Opiate Substitution Treatment / Q000379:methods* / Q000706:statistics & numerical data; D009293:Opioid-Related Disorders / Q000188:drug therapy* / Q000534:rehabilitation; D010352:Patient Dropouts; D019338:Polypharmacy; D011247:Pregnancy; D011248:Pregnancy Complications; D012959:Socioeconomic Factors; D055815:Young Adult
chemical_list: D002047:Buprenorphine; D008691:Methadone