title: Recombination is associated with an outbreak of novel highly pathogenic porcine reproductive and respiratory syndrome viruses in China.
abstract: In 2009 to 2010, there was a marked increase in the number of infections with highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) in China. Through phylogenetic analysis, we show that viruses from this outbreak originated from a single recombination event, illustrating the potential importance of this process for disease emergence.
authors.affiliation: Sydney Emerging Infections and Biosecurity Institute, School of Biological Sciences and Sydney Medical School, The University of Sydney, NSW, Australia.
authors.forename: Mang
authors.initials: M
authors.lastname: Shi
authors.forename: Edward C
authors.initials: EC
authors.lastname: Holmes
authors.forename: Manreetpal Singh
authors.initials: MS
authors.lastname: Brar
authors.forename: Frederick Chi-Ching
authors.initials: FC
authors.lastname: Leung
mesh_terms: D000818:Animals; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D016679:Genome, Viral; D010802:Phylogeny; D019318:Porcine Reproductive and Respiratory Syndrome / Q000453:epidemiology* / Q000235:genetics / Q000821:virology; D019316:Porcine respiratory and reproductive syndrome virus / Q000472:pathogenicity*; D012367:RNA, Viral / Q000235:genetics; D011995:Recombination, Genetic; D013552:Swine
chemical_list: D012367:RNA, Viral