title: Intraocular cysts of toxoplasma gondii in patients with necrotizing retinitis following periocular/intraocular triamcinolone injection.
abstract: OBJECTIVE
  To report the detection of Toxoplasma gondii cysts in intraocular aspirates of patients with necrotizing retinitis following periocular/intraocular corticosteroid injection.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Two patients (2 eyes) with widespread necrotizing retinitis in a steroid-exposed eye posed a diagnostic challenge and underwent pars plana vitrectomy (PPV). Intraocular samples (vitreous fluid, retinal tissue, and subretinal aspirate in case 1, and vitreous fluid in case 2) were subjected to cytological examination.
  
  
  RESULTS
  The subretinal aspirate (case 1) revealed encysted bradyzoites of Toxoplasma gondii. Vitreous fluid (case 2) tested positive for anti-toxoplasma antibodies and the smear showed encysted forms of Toxoplasma gondii on cytology. CONCLUSION. Toxoplasma gondii cysts were detected in eyes with necrotizing retinitis that developed secondary to injudicious use of corticosteroids.
authors.affiliation: Department of Cytology & Gynecological Pathology and.
authors.forename: Raje
authors.initials: R
authors.lastname: Nijhawan
authors.forename: Reema
authors.initials: R
authors.lastname: Bansal
authors.forename: Nalini
authors.initials: N
authors.lastname: Gupta
authors.forename: Nikhil
authors.initials: N
authors.lastname: Beke
authors.forename: Pandurang
authors.initials: P
authors.lastname: Kulkarni
authors.forename: Amod
authors.initials: A
authors.lastname: Gupta
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D015864:Panuveitis / Q000188:drug therapy; D012173:Retinitis / Q000139:chemically induced* / Q000150:complications / Q000601:surgery; D014122:Toxoplasma / Q000276:immunology / Q000302:isolation & purification*; D014126:Toxoplasmosis, Ocular / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D014221:Triamcinolone / Q000008:administration & dosage / Q000009:adverse effects*; D014821:Vitrectomy
chemical_list: D000913:Antibodies, Protozoan; D014221:Triamcinolone