title: Ultrasensitive fluorescence detection of bleomycin via exonuclease III-aided DNA recycling amplification.
abstract: A "signal on" approach for ultrasensitive detection of bleomycin was developed by bleomycin-Fe(II) induced hairpin DNA scission to release its loop, which was subsequently recycled with the aid of exonuclease III and a probe to amplify the detectable fluorescent signal.
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China.
authors.forename: Fenglei
authors.initials: F
authors.lastname: Gao
authors.forename: Jianping
authors.initials: J
authors.lastname: Lei
authors.forename: Huangxian
authors.initials: H
authors.lastname: Ju
mesh_terms: D001761:Bleomycin / Q000032:analysis* / Q000378:metabolism; D004247:DNA / Q000032:analysis / Q000378:metabolism*; D005090:Exodeoxyribonucleases / Q000378:metabolism*; D021141:Nucleic Acid Amplification Techniques; D013050:Spectrometry, Fluorescence
chemical_list: D001761:Bleomycin; D004247:DNA; D005090:Exodeoxyribonucleases; C020133:exodeoxyribonuclease III