title: [A novel naphthalene derivative from Aloe barbadensis].
abstract: To investigate the chemical constituents of A. barbadensis, aqueous extract of the plant was subjected to preparative medium pressure liquid chromatography (MPLC). The chemical structures were mainly determined by spectroscopic evidences (UV, IR, HR-MS, 1H NMR, 13C NMR, HSQC, 1H-1H COSY and HMBC) and chemical methods. A new O, O, O-triglucosylated naphthalene derivative, together with two known 6-phenyl-2-pyrone derivatives and four 5-methylchromones, were isolated and identified as 1-((3-((4- O-beta-D-glucopyranosyl)-beta-D-xylopyranosyloxymethyl)-1-hydroxy-8-alpha-L-rhamnopyranosyloxy)naphthalene-2-y])-ethanone (1), 10-O-beta-D-glucopyranosyl aloenin (2), aloenin B (3), aloesin (4), 8-C-glucosyl-(R)-aloesol (5), 8-C-glucosyl-7-O-methyl-(S)-aloesol (6), and isoaloeresin D (7). Compound 1 is a novel naphthalene derivative and named as aloveroside B, compounds 2-3 are isolated from this Aloe species for the first time.
authors.affiliation: Lab of Pharmaceutical Analysis, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
authors.forename: Xiao-Fang
authors.initials: XF
authors.lastname: Wu
authors.forename: Jin-Zhi
authors.initials: JZ
authors.lastname: Wan
authors.forename: Bing-Jun
authors.initials: BJ
authors.lastname: Luo
authors.forename: Miao-Rong
authors.initials: MR
authors.lastname: Yang
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: Ding
authors.forename: Jia-Sheng
authors.initials: JS
authors.lastname: Zhong
mesh_terms: D000504:Aloe / Q000737:chemistry*; D002867:Chromones / Q000737:chemistry / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D002867:Chromones; D005960:Glucosides; D006027:Glycosides; D009281:Naphthalenes; C000604297:aloveroside B; C069868:aloesin