title: Lifting the veil on amyloid drug design.
abstract: High resolution structures and computational methods have been used to identify compounds that prevent amyloid fibrils associated with Alzheimer's disease from dissociating into toxic species.
authors.affiliation: is in the Center for Biotechnology & Interdisciplinary Studies, Department of Chemical and Biological Engineering , Rensselaer Polytechnic Institute , New York , United States tillek@rpi.edu.
authors.forename: Kathryn E
authors.initials: KE
authors.lastname: Tiller
authors.forename: Peter M
authors.initials: PM
authors.lastname: Tessier
mesh_terms: D016229:Amyloid beta-Peptides / Q000633:toxicity*; D006801:Humans
chemical_list: D016229:Amyloid beta-Peptides
keywords: Alzheimer's disease; Other; amyloid fiber; computational biology; drug discovery; ligand docking