title: Pain, sleep disturbances, and functional limitations in people living with HIV/AIDS-associated distal sensory peripheral neuropathy.
abstract: BACKGROUND
  Pain, sleep, and functional disturbances are a common occurrence in people living with HIV/AIDS-related distal sensory peripheral neuropathy (PLWHA-DSPN) yet lack group classification and quantification.
  
  
  METHODS
  A total of 46 PLWHA-DSPN were recruited, as part of a 2-group intervention study, to complete the Neuropathic Pain Scale and the Pittsburgh Sleep Quality Index (PSQI) questionnaires. The participant's performance during a forward reach task and walking distance in 6 minutes was recorded as a measure of function.
  
  
  RESULTS
  The pain (60.77 +/- 17.85) and sleep (14.62 +/- 4.28) scores denote marked pain and sleep disturbances, compared to seronegative, age-matched individuals. The ambulation distance was limited (243.99 +/- 141.04 m) and inversely associated with the PSQI-sleep efficiency subscale (rs = -.35, P < .05). The average reaching distances measured (36.07 +/- 7.37 cm) were similar to seronegative, age-matched individuals. Pain, sleep, and functional measures exhibited significant associations.
  
  
  CONCLUSIONS
  The data collected suggest that PLWHA-DSPN report moderate-to-severe pain and significant sleep disturbances and exhibit limited ambulation distances.
authors.forename: Roberto
authors.initials: R
authors.lastname: Sandoval
authors.forename: Toni
authors.initials: T
authors.lastname: Roddey
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Giordano
authors.forename: Katy
authors.initials: K
authors.lastname: Mitchell
authors.forename: Carolyn
authors.initials: C
authors.lastname: Kelley
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D005080:Exercise Test; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000453:epidemiology*; D010147:Pain Measurement; D010523:Peripheral Nervous System Diseases / Q000453:epidemiology*; D012893:Sleep Wake Disorders / Q000453:epidemiology*; D013647:Task Performance and Analysis