title: Microtubule motors: a new hope for kinesin-5 inhibitors?
abstract: A new study demonstrates that two microtubule plus end-directed kinesins can oppose each other. The cause of this apparent contradiction is the specific orientation of microtubules on which each motor exerts its force.
authors.affiliation: Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. Aaron_Groen@hms.harvard.edu
authors.forename: Aaron
authors.initials: A
authors.lastname: Groen
mesh_terms: D002453:Cell Cycle; D006801:Humans; D016547:Kinesins / Q000235:genetics*; D018386:Kinetochores / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D008941:Spindle Apparatus / Q000378:metabolism*
chemical_list: C486567:KIF15 protein, human; D016547:Kinesins