title: Effectiveness of green tea mouthwash in postoperative pain control following surgical removal of impacted third molars: double blind randomized clinical trial.
abstract: BACKGROUND
  Pain following surgical removal of impacted molars has remained an important concern among practitioners. Various protocols have been proposed to reduce postoperative pain. However, each one has special side effects and limitations. As green tea possesses anti-inflammatory and antibacterial properties, the aim of the current study was to evaluate the effectiveness of green tea mouthwash in controlling postoperative pain.
  
  
  METHODS
  In a study with split-mouth and double blind design, 44 patients in need of bilateral removal of impacted third molars underwent randomized surgical extraction; following one surgery patients rinsed with a green tea mouthwash from the first to seventh postoperative day and after other extraction rinsed with placebo mouthwash in the same duration. Both patients and surgeon were blinded to the type of mouthwash. The predictor variable was type of mouthwash and primary outcome variable was postoperative pain measured by visual analogue scale (VAS) during first week after surgery. In addition, number of analgesics patients used after surgery recorded. To measure the effect of green tea mouthwash, repeated measures test with confidence interval of 95% was performed.
  
  
  RESULTS
  Total of 43 patients with mean age of 24 years underwent total of 86 surgeries. VAS value had no statistically difference prior rinsing among groups (P-value > 0.05). However, the mean value of VAS following rinsing with green tea was statistically lower than placebo in postoperative days of 3-7 (P-value < 0.05). In addition, while rinsing with green tea, patients took significantly lower number of analgesics after surgery (P-value < 0.05). No side effects reported.
  
  
  CONCLUSIONS
  Green tea mouthwash could be an appropriate and safe choice to control postoperative pain after third molar surgery.
authors.forename: Majid
authors.initials: M
authors.lastname: Eshghpour
authors.forename: Hamed
authors.initials: H
authors.lastname: Mortazavi
authors.forename: Naser
authors.initials: N
authors.lastname: Mohammadzadeh Rezaei
authors.forename: AmirHossein
authors.initials: A
authors.lastname: Nejat
mesh_terms: D000293:Adolescent; D000328:Adult; D000700:Analgesics / Q000627:therapeutic use*; D028241:Camellia sinensis / Q000737:chemistry*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008964:Molar, Third / Q000601:surgery*; D009067:Mouthwashes / Q000627:therapeutic use*; D010149:Postoperative Pain / Q000188:drug therapy*; D010936:Plant Extracts / Q000627:therapeutic use*; D014081:Tooth Extraction / Q000009:adverse effects*; D014095:Tooth, Impacted / Q000601:surgery; D055815:Young Adult
chemical_list: D000700:Analgesics; D009067:Mouthwashes; D010936:Plant Extracts