title: Comparison of macroscopic one-layer over number 1 nylon suture vasovasostomy with the standard two-layer microsurgical procedure.
abstract: OBJECTIVE
  To compare the outcomes of macroscopic one-layer vasovasostomy (MOLVV) with those of two-layer microsurgical vasovasostomy (TLMVV).
  
  
  METHODS
  Standard TLMVV was performed in 112 men (Group 1), while MOLVV was performed in 94 patients. All of the MOLVVs were performed with number 1 nylon suture as a temporary stent. The outcome measures were as follows: patency rate, pregnancy rate, operation time, total procedure cost, and complications.
  
  
  RESULTS
  The mean operation duration was 114 ± 10 min for the TLMVV technique, and 74 ± 5 min for the MOLVV procedure (P = 0.024). In patients who underwent vasal patency at 6-month postoperative period, the median sperm density (10⁶/mL) was 28.3 and 27.7 in Groups 1 and 2, respectively (P = 0.62). At the same time, the median total motile sperm count (× 10⁶) was 39.4 and 32.6 in two-layer microsurgical and one-layer macroscopic groups, respectively (P = 0.47). Patency rates were 82.1% in Group 1 and 77.7% in Group 2, which were not significantly different (P = 0.21). The pregnancy rate was 28.4% for patients in Group 1 and 26.7% for patients in Group 2 (P = 0.38).
  
  
  CONCLUSIONS
  There were no significant differences in terms of patency and pregnancy rates between MOLVV and TLMVV methods, but the MOLVV technique offers a decreased cost and operative time, and a simplified procedure.
authors.affiliation: Clinical Center for Urological Disease Diagnosis and Private Clinic Specializing in Urological and Andrological Genetics , Tehran , Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Safarinejad
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Lashkari
authors.forename: Seyyed Alaeddin
authors.initials: SA
authors.lastname: Asgari
authors.forename: Alireza
authors.initials: A
authors.lastname: Farshi
authors.forename: Ali Reza
authors.initials: AR
authors.lastname: Babaei
mesh_terms: D000328:Adult; D017046:Cost Savings; D003365:Costs and Cost Analysis; D005260:Female; D017048:Health Care Costs; D006801:Humans; D007492:Iran / Q000453:epidemiology; D059012:Lost to Follow-Up; D008297:Male; D008866:Microsurgery / Q000009:adverse effects* / Q000191:economics; D008875:Middle Aged; D061646:Operative Time; D011183:Postoperative Complications / Q000517:prevention & control; D011247:Pregnancy; D018873:Pregnancy Rate; D055101:Semen Analysis; D014669:Vasovasostomy / Q000009:adverse effects / Q000191:economics / Q000379:methods*