title: Analytical strategies based on chromatography-mass spectrometry for the determination of estrogen-mimicking compounds in food.
abstract: Food safety can be compromised by the presence of a wide variety of substances, deriving from both natural and anthropogenic sources. Among these substances, compounds exhibiting various degrees of estrogenic activity have been widely studied in environmental samples, whereas less attention has been devoted to food matrices. The aim of the present review is to give a general overview on the recent analytical methods based on gas or liquid chromatography coupled to mass spectrometry for the determination of estrogen-like compounds in foods, including new developments, improvements and upcoming trends in the field. Attention will be focused on four representative groups of compounds, i.e. natural and synthetic estrogens, mycoestrogens, phytoestrogens, and alkylphenols.
authors.affiliation: Dipartimento di Chimica, Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy.
authors.forename: Anna Laura
authors.initials: AL
authors.lastname: Capriotti
authors.forename: Chiara
authors.initials: C
authors.lastname: Cavaliere
authors.forename: Valentina
authors.initials: V
authors.lastname: Colapicchioni
authors.forename: Susy
authors.initials: S
authors.lastname: Piovesana
authors.forename: Roberto
authors.initials: R
authors.lastname: Samperi
authors.forename: Aldo
authors.initials: A
authors.lastname: Laganà
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D052244:Endocrine Disruptors / Q000032:analysis*; D045166:Estradiol Congeners / Q000032:analysis*; D005504:Food Analysis / Q000379:methods*; D059022:Food Safety; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D048789:Phytoestrogens / Q000032:analysis*
chemical_list: D052244:Endocrine Disruptors; D045166:Estradiol Congeners; D048789:Phytoestrogens
keywords: Alkylphenols; Estrogens; Food safety; Mass spectrometry; Mycoestrogens; Phytoestrogens