title: Cardiac resynchronization therapy in a patient with amyloid cardiomyopathy.
abstract: Cardiac involvement in systemic light chain amyloidosis carries poor prognosis. Amyloid deposition in the myocardium can alter regional left ventricular contraction and cause dyssynchrony. Cardiac resynchronization therapy (CRT) is an effective treatment strategy for patients with advanced heart failure and echocardiographic dyssynchrony. We report a clinical and echocardiographic response of a patient with amyloid cardiomyopathy, treated with a combination of chemotherapy and CRT.
authors.affiliation: Department of Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia. davidzizek@yahoo.com
authors.forename: David
authors.initials: D
authors.lastname: Zizek
authors.forename: Marta
authors.initials: M
authors.lastname: Cvijić
authors.forename: Igor
authors.initials: I
authors.lastname: Zupan
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis / Q000628:therapy*; D001706:Biopsy; D058406:Cardiac Resynchronization Therapy / Q000379:methods*; D009202:Cardiomyopathies / Q000000981:diagnostic imaging / Q000628:therapy*; D004452:Echocardiography; D005500:Follow-Up Studies; D006801:Humans; D000075363:Immunoglobulin Light-chain Amyloidosis; D008297:Male; D012867:Skin / Q000473:pathology