title: GET-SERF, a new gradient encoded SERF experiment for the trivial edition of 1H-19F couplings.
abstract: A new spatially encoded heteronuclear (1)H-(19)F selective refocusing NMR experiment (GET-SERF) is proposed. This sequence allows editing in one single 2D experiment all couplings between a selected fluorine site and all the proton nuclei of the molecule. Its efficiency is illustrated in the case of diflunisal, a difluorinated anti-inflammatory drug, in isotropic and anisotropic media.
authors.affiliation: Equipe de RMN en milieu orienté, ICMMO, UMR 8182, Université Paris-Sud. 15, Georges Clemenceau, Orsay, France.
authors.forename: Maria Enrica
authors.initials: ME
authors.lastname: Di Pietro
authors.forename: Christie
authors.initials: C
authors.lastname: Aroulanda
authors.forename: Denis
authors.initials: D
authors.lastname: Merlet
keywords: Couplings extraction; Fluorinated compounds; NMR spectroscopy; SERF experiment; Spatial encoding