title: Factors influencing weight gain in an Asian population of psychiatric inpatients: a retrospective study in Taiwan.
abstract: BACKGROUND
  The aim of this study was to investigate the factors associated with weight gain by psychiatric inpatients in short-term treatment.
  
  
  METHODS
  A total of 378 medical records were reviewed, and sociodemographic, clinical, and baseline biochemical data from 221 psychiatric inpatients were analyzed.
  
  
  RESULTS
  Evaluation of baseline characteristics indicated that the following were significant predictors of weight gain: Axis I diagnosis, treatment with second-generation antipsychotics and mood stabilizers, length of stay, admission body weight, low-density lipoprotein value, triglyceride level, and triglyceride/high-density lipoprotein ratio. Multiple linear regression analysis showed that the independent predictors of weight gain were length of stay and taking both a second-generation antipsychotic and a mood stabilizer. The triglyceride/high-density lipoprotein ratio was an influencing factor inversely associated with weight gain (P = 0.063).
  
  
  CONCLUSIONS
  Length of hospitalization and polypharmacy strongly predicted weight gain among psychiatric inpatients receiving short-term treatment.
authors.affiliation: Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taiwan; School of Medicine, Chang Gung University, Taoyuan, Taiwan.
authors.forename: Yu-Tsung
authors.initials: YT
authors.lastname: Liu
authors.forename: Yeuk-Lun
authors.initials: YL
authors.lastname: Chau
authors.forename: Shih-Chieh
authors.initials: SC
authors.lastname: Hsu
authors.forename: Chun-Lin
authors.initials: CL
authors.lastname: Chu
authors.forename: Ching-Yen
authors.initials: CY
authors.lastname: Chen
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D007297:Inpatients; D008297:Male; D001523:Mental Disorders / Q000097:blood / Q000188:drug therapy; D012189:Retrospective Studies; D013624:Taiwan; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D014150:Antipsychotic Agents; D002784:Cholesterol
keywords: length of hospitalization; polypharmacy; psychiatric inpatient, risk factor triglyceride/high-density lipoprotein ratio; weight gain