title: Management of irritable bowel syndrome with constipation: a flexible approach to treating a complex condition with multiple symptoms.
abstract: Irritable bowel syndrome is a heterogeneous disease with a complex underlying pathophysiology and multiple symptoms - that is, clinical manifestation patterns. As such, management of irritable bowel syndrome requires a flexible approach tailored to the individual patient. This article reviews rational, evidence-based management strategy and treatment options for this variable condition.
authors.affiliation: Medizinische Klinik, Israelitisches Krankenhaus in Hamburg, Orchideenstieg 14, 22297 Hamburg, Germany. p.layer@ik-h.de
authors.forename: Peter
authors.initials: P
authors.lastname: Layer
mesh_terms: D015746:Abdominal Pain / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D003248:Constipation / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D003672:Defecation / Q000187:drug effects*; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D012307:Risk Factors; D040242:Risk Reduction Behavior; D016896:Treatment Outcome
chemical_list: D005765:Gastrointestinal Agents