title: Hospitalization costs ofTAVI in one Belgian university hospital.
abstract: OBJECTIVE
  Considering the sizeable cost of transcatheter aortic valve implantation (TAVI) and conflicting cost-effectiveness studies, it is useful to gain more insight into the cost structure of the TAVI hospitalization. This study provides such a cost analysis and starts to evaluate options to soften the hospitalization cost burden in order to make TAVI economically more feasible.
  
  
  METHODS
  Costs forTAVI hospitalization in the University Hospital of Antwerp were analysed uni- and bivariately. Graphical and numerical displays of the data are supplemented with the non-parametric Wilcoxon rank sum statistic and Spearman rank rho correlation.
  
  
  RESULTS
  Overall, 47 percent of the cost could be attributed to the implanted valve and 21 percent was accounted for by the room costs. Further, costs seemed highly insensitive to pre-existing patient characteristics. Only patients with pulmonary hypertension were characterized with systematically higher costs (Wilcoxon rank sum P-value of 0.049). Complications related to TAVI had a significant upward impact on the costs and there was also evidence for a learning effect on total costs.
  
  
  CONCLUSIONS
  In general the analyses showed that only limited options remain for cost reduction of the TAVI hospitalization cost. The most promising option is the reduction of the valve price. Avoidance of complications is hard to achieve given the current state of the art although this would significantly reduce overall costs.
authors.affiliation: Dept. of Economics, University of Antwerp, Antwerpen, Belgium. Raf.VanGestel@ua.ac.be
authors.forename: Raf
authors.initials: R
authors.lastname: Van Gestel
authors.forename: Diana
authors.initials: D
authors.lastname: De Graeve
authors.forename: Christiaan
authors.initials: C
authors.lastname: Vrints
authors.forename: Inez
authors.initials: I
authors.lastname: Rodrigus
authors.forename: Johan
authors.initials: J
authors.lastname: Bosmans
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000191:economics / Q000601:surgery*; D001530:Belgium; D006328:Cardiac Catheterization / Q000191:economics*; D003362:Cost-Benefit Analysis; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000191:economics* / Q000379:methods; D017722:Hospital Charges / Q000706:statistics & numerical data*; D006760:Hospitalization / Q000191:economics*; D006785:Hospitals, University / Q000191:economics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012042:Registries; D012189:Retrospective Studies