title: Double jeopardy: Blepharophimosis syndrome with congenital nasolacrimal duct obstruction in twins.
abstract: OBJECTIVE
  Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) is an autosomal dominant disorder characterized by bilateral ptosis with poor levator function, epicanthus inversus and shortened horizontal palpebral fissures.
  
  
  METHODS
  Eighteen -month -old twin sisters presented with history of watering from their left eyes since birth. Examination revealed features of BPES with left congenital nasolacrimal duct obstruction in both.
  
  
  RESULTS
  the twins underwent therapeutic probing, which was successful in one and failed in the other. the second child was subsequently managed by external dacryocystorhinostomy.
  
  
  CONCLUSIONS
  To our knowledge, this is the first report of Blepharophimosis syndrome with congenital nasolacrimal duct obstruction occurring in twin sisters.
authors.affiliation: Department of Orbit, Oculoplasty, Reconstructive & Aesthetic Services, Sankara Nethralaya, Medical Research Foundation , Chennai , India.
authors.forename: Bipasha
authors.initials: B
authors.lastname: Mukherjee
authors.forename: Md Shahid
authors.initials: MS
authors.lastname: Alam
mesh_terms: D016569:Blepharophimosis / Q000175:diagnosis* / Q000601:surgery*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D012868:Skin Abnormalities / Q000175:diagnosis* / Q000601:surgery*; D014427:Twins; D014564:Urogenital Abnormalities