title: [Combined therapy of lapatinib and capecitabine effective against local recurrence of breast cancer].
abstract: A 67-year-old woman after mastectomy was afflicted with local recurrence of left breast cancer during adjuvant trastuzumab therapy. Oral administration of lapatinib and capecitabine served to distinguish the recurrent tumor and also reduce the patient's distressing symptoms. This combined anti-cancer therapy may be available for patients with breast cancer for whom trastuzumab therapy was not adequately effective.
authors.affiliation: Dept. of Surgery, Fukuoka Higashi Medical Center.
authors.forename: Tadahiro
authors.initials: T
authors.lastname: Nozoe
authors.forename: Emiko
authors.initials: E
authors.lastname: Nozoe
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Iguchi
authors.forename: Shuhei
authors.initials: S
authors.lastname: Ito
authors.forename: Takefumi
authors.initials: T
authors.lastname: Ohga
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Koga
authors.forename: Takahiro
authors.initials: T
authors.lastname: Ezaki
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D000069287:Capecitabine; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000188:drug therapy*; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000031:analogs & derivatives; D006801:Humans; D000077341:Lapatinib; D011799:Quinazolines / Q000008:administration & dosage; D012008:Recurrence; D014057:Tomography, X-Ray Computed
chemical_list: D011799:Quinazolines; D000077341:Lapatinib; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil