title: Persistence of histoplasma in adrenals 7 years after antifungal therapy.
abstract: Adrenal histoplasmosis is an uncommon cause for adrenal insufficiency. The duration of treatment for adrenal histoplasmosis is not clear. Existing treatment regimens advocate antifungals given for periods ranging from 6 months to 2 years. We report here a rare case who showed persistence of histoplasma in adrenal biopsy 7 years after being initially treated with itraconazole for 9 months. This calls for a prolonged therapy with regular review of adrenal morphology and histology in these patients.
authors.affiliation: Endocrinology Unit, Dr. RML Hospital, Delhi, India.
authors.forename: Deepak
authors.initials: D
authors.lastname: Kothari
authors.forename: Shweta
authors.initials: S
authors.lastname: Chopra
authors.forename: Minakshi
authors.initials: M
authors.lastname: Bhardwaj
authors.forename: Ajay K
authors.initials: AK
authors.lastname: Ajmani
authors.forename: Bindu
authors.initials: B
authors.lastname: Kulshreshtha
keywords: Addison's disease; antifungal therapy; histoplasma