title: Relation of visceral and subcutaneous adipose tissue to bone mineral density in chinese women.
abstract: The relationship between adipose and bone tissues is still being debated. The purpose of our study was to evaluate whether the distribution and volume of abdomen adipose tissue are correlated to trabecular bone mineral density in the lumbar spine. In this cross-sectional study, 320 Chinese women, being divided into two groups according to age ≥55 years and <55 years, were evaluated with quantitative computed tomography (QCT) of the spine to simultaneously evaluate the average trabecular BMD of L2-L4, VAT, and SAT. Possible covariates of height, weight, age, and comorbidities were considered. In the <55-year-old sample, multiple linear regression analyses indicated that VAT volume was negatively correlated to trabecular BMD (P value = 0.0003) and SAT volume had no correlation to trabecular BMD. In contrast, there was no significant correlation between VAT or SAT and BMD in the ≥55-year-old sample. Our results indicate that high VAT volume is associated with low BMD in Chinese women aged <55 years and SAT has no relation with BMD.
authors.affiliation: Department of Radiology, Beijing Jishuitan Hospital, Beijing 100035, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Li
authors.initials: L
authors.lastname: Xu
authors.forename: Xiaoguang
authors.initials: X
authors.lastname: Cheng
authors.forename: Yimin
authors.initials: Y
authors.lastname: Ma
authors.forename: Dan
authors.initials: D
authors.lastname: Liu
authors.forename: Zhe
authors.initials: Z
authors.lastname: Guo
authors.forename: Yongbin
authors.initials: Y
authors.lastname: Su
authors.forename: Qianqian
authors.initials: Q
authors.lastname: Wang