title: [A case of triple-negative breast cancer achieved pCR by epirubicin and cyclophosphamide(EC)therapy followed by gemcitabine plus paclitaxel combination preoperative therapy].
abstract: A 59-year-old woman was diagnosed with triple-negative breast cancer(TNBC)(T2N0M0)and treated with primary systemic therapy. The patient was treated with 4 courses of epirubicin and cyclophosphamide(EC)therapy every 3 weeks, followed by weekly gemcitabine-paclitaxel combination therapy. As she was judged to have achieved a partial response(PR) by ultrasound and CT examination after eight courses, she underwent partial resection of the left breast. CR was revealed by the pathological examination of the resected specimen. Gemcitabine-paclitaxel combination therapy seems to be a one of the useful preoperative chemotherapies for TNBC.
authors.affiliation: Dept. of Surgery, Hoshi General Hospital, Japan.
authors.forename: Motonobu
authors.initials: M
authors.lastname: Saito
authors.forename: Shotaro
authors.initials: S
authors.lastname: Fujita
authors.forename: Takeshi
authors.initials: T
authors.lastname: Sakuma
authors.forename: Masami
authors.initials: M
authors.lastname: Matsuzaki
authors.forename: Naoto
authors.initials: N
authors.lastname: Katagata
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Watanabe
authors.forename: Seiichi
authors.initials: S
authors.lastname: Takenoshita
authors.forename: Tadashi
authors.initials: T
authors.lastname: Nomizu
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D015251:Epirubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage; D012074:Remission Induction; D000093542:Gemcitabine
chemical_list: D003841:Deoxycytidine; D015251:Epirubicin; D003520:Cyclophosphamide; D017239:Paclitaxel; D000093542:Gemcitabine