title: A thymine tetrad assembly templated from thymidylic acid.
abstract: A template tetra-coupled with thymidylic acid through a phosphate linkage was characterized in methanol for emergent properties of nucleobase tetrad formation. Intramolecular hydrogen bonded base pairing in the absence of a cation was indicated for the thymidylic acid species supporting a monomeric template-assembled structure. Thus, an initial report of a stabilized individual thymine tetrad assembly is presented here. Consistent with previous investigations, a deoxyguanylic acid variant templated an analogous methanolic monomeric G-tetrad in comparison to the thymine species.
authors.affiliation: Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC, Canada, V6T 1Z1.
authors.forename: Grant A L
authors.initials: GA
authors.lastname: Bare
authors.forename: John C
authors.initials: JC
authors.lastname: Sherman
mesh_terms: D006860:Hydrogen Bonding; D015394:Molecular Structure; D013938:Thymidine Monophosphate / Q000737:chemistry*; D013941:Thymine / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D013938:Thymidine Monophosphate; D013941:Thymine