title: An unusual presentation of giant pilomatrixoma in an adult patient.
abstract: BACKGROUND
  Pilomatrixoma (OMIM ID #132600) is a benign cutaneous tumor originating from the pilosebaceous follicle and characterized by the presence of subcutaneous nodules of up to 3.0 cm in diameter, usually on the head, neck and upper extremities. It is most common in the first two decades of life and after the age of 60.
  
  
  METHODS
  An adult female patient was evaluated, presenting a solid tumoral lesion with erythematous surface and purplish tone, with approximately 7.5 x 5.0 cm in size, in the interscapulovertebral region. It was thought to be an epidermoid cyst, sarcoma, calcified hemangioma, giant dermatofibroma, or nodular basal cell carcinoma. The resection of the lesion was carried out and, at the histological examination, specific details were observed that led to the diagnosis of pilomatrixoma.
  
  
  CONCLUSIONS
  Pilomatrixoma should be suspected in the differential diagnosis of giant adnexal tumors.
authors.affiliation: Department of Clinical Medicine, School of Medical Sciences, Universidade de Marília (UNIMAR), Marília, São Paulo state, Brazil;
authors.forename: Mariam Patrícia Auada
authors.initials: MP
authors.lastname: Souto
authors.forename: Marcus de Medeiros
authors.initials: Mde M
authors.lastname: Matsushita
authors.forename: Graziela de Macedo
authors.initials: Gde M
authors.lastname: Matsushita
authors.forename: Luís Ricardo Martinhão
authors.initials: LR
authors.lastname: Souto
keywords: adnexal tumor; hair follicle; pilomatricoma; pilomatrixoma; sebaceous gland; tumor