title: Does prophylactic stent insertion to the common bile duct during endoscopic retrograde cholangiopancreatography (ERCP) before cholecystectomy have any impact on the rate of biliary complications?
abstract: BACKGROUND
  Patients with choledochocystolithiasis generally undergo endoscopic sphincterotomy (ES) followed by elective cholecystectomy. They can experience the development of recurrent biliary events while waiting for their scheduled surgery.
  
  
  OBJECTIVE
  This study investigated whether stent insertion before cholecystectomy influences the rate of complications.
  
  
  METHODS
  The study compared retrospective and prospective groups of patients with choledochocystolithiasis who underwent ES with or without prophylactic common bile duct stent insertion before cholecystectomy. The rate of emergency cholecystectomies and biliary complications during the waiting period before the elective procedure was analyzed.
  
  
  RESULTS
  For the study, 162 patients with choledochocystolithiasis who underwent endoscopic retrograde cholangiopancreatography (ERCP) with ES were divided to two subgroups. Group A included 52 patients with stent insertion (mean age, 58.3 ± 19.4 years), and group B included 110 patients with no stent insertion (mean age, 61.4 ± 17.7 years) (p = 0.32). Males made up 33.3% of group A and 53.7% of group B (p = 0.018). The median time to elective cholecystectomy (open or laparoscopic) was 41.5 days for the patients without bile duct stent insertion before cholecystectomy and 53.5 days for the patients who had the stent insertion before cholecystectomy (p = 0.63). Repeat emergency ERCP due to acute cholangitis was 5.6% in group A and 1.0% in group B (p = 0.43). Emergency cholecystectomy rates due to acute cholecystitis after ES were 15.4% in group A and 14.5% in group B (p = 1.00). No mortality occurred.
  
  
  CONCLUSIONS
  According to the study findings, prophylactic stent insertion during ERCP before cholecystectomy has no impact on biliary complications.
authors.affiliation: Department of Gastroenterology, Hillel-Yaffe Medical Center, P.O. Box 169, 38100, Hadera, Israel.
authors.forename: V
authors.initials: V
authors.lastname: Verzhbitsky
authors.forename: A R
authors.initials: AR
authors.lastname: Zeina
authors.forename: R
authors.initials: R
authors.lastname: Depsames
authors.forename: B
authors.initials: B
authors.lastname: Ovadia
authors.forename: O
authors.initials: O
authors.lastname: Atia
authors.forename: Z
authors.initials: Z
authors.lastname: Fireman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods*; D002763:Cholecystectomy / Q000379:methods*; D042883:Choledocholithiasis / Q000000981:diagnostic imaging / Q000601:surgery*; D003135:Common Bile Duct / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007557:Israel / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology* / Q000517:prevention & control*; D012189:Retrospective Studies; D015607:Stents; D055815:Young Adult