title: [RSF model optimization and its application to brain tumor segmentation in MRI].
abstract: Magnetic resonance imaging (MRI) is usually obscure and non-uniform in gray, and the tumors inside are poorly circumscribed, hence the automatic tumor segmentation in MRI is very difficult. Region-scalable fitting (RSF) energy model is a new segmentation approach for some uneven grayscale images. However, the level set formulation (LSF) of RSF model is not suitable for the environment with different grey level distribution inside and outside the intial contour, and the complex intensity environment of MRI always makes it hard to get ideal segmentation results. Therefore, we improved the model by a new LSF and combined it with the mean shift method, which can be helpful for tumor segmentation and has better convergence and target direction. The proposed method has been utilized in a series of studies for real MRI images, and the results showed that it could realize fast, accurate and robust segmentations for brain tumors in MRI, which has great clinical significance.
authors.affiliation: Digital Medical Research Center, Fudan University, Shanghai 200032, China.
authors.forename: Zhaoning
authors.initials: Z
authors.lastname: Cheng
authors.forename: Zhijian
authors.initials: Z
authors.lastname: Song
mesh_terms: D000465:Algorithms; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008962:Models, Theoretical