title: An ultrasensitive biosensor for DNA detection based on hybridization chain reaction coupled with the efficient quenching of a ruthenium complex to CdTe quantum dots.
abstract: A highly sensitive and selective DNA biosensor based on hybridization chain reaction is described, which combines CdTe quantum dots (QDs) and a ruthenium complex. Based on the variation of fluorescence signals of the CdTe QDs, the target DNA is determined.
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, PR China.
authors.forename: Yufei
authors.initials: Y
authors.lastname: Liu
authors.forename: Ming
authors.initials: M
authors.lastname: Luo
authors.forename: Ji
authors.initials: J
authors.lastname: Yan
authors.forename: Xia
authors.initials: X
authors.lastname: Xiang
authors.forename: Xinghu
authors.initials: X
authors.lastname: Ji
authors.forename: Guohua
authors.initials: G
authors.lastname: Zhou
authors.forename: Zhike
authors.initials: Z
authors.lastname: He
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D019187:Cadmium Compounds / Q000737:chemistry*; D056831:Coordination Complexes / Q000737:chemistry*; D004247:DNA / Q000032:analysis*; D004279:DNA, Viral / Q000032:analysis; D004867:Equipment Design; D027383:Papillomaviridae / Q000235:genetics; D045663:Quantum Dots; D012428:Ruthenium / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013050:Spectrometry, Fluorescence; D013691:Tellurium / Q000737:chemistry*
chemical_list: D019187:Cadmium Compounds; D056831:Coordination Complexes; D004279:DNA, Viral; D012428:Ruthenium; D004247:DNA; D013691:Tellurium; C028337:cadmium telluride