title: Effect of consecutive intragastric balloon (BIB®) plus diet versus single BIB® plus diet on eating disorders not otherwise specified (EDNOS) in obese patients.
abstract: BACKGROUND
  Eating disorders are a group of conditions characterised by abnormal eating habits. Greater than 50 % of patients with eating disorders have an 'eating disorder not otherwise specified' (EDNOS). No specific tools exist to evaluate EDNOS, and patients are identified only with a diagnosis of exclusion from the other eating disorders. The BioEnterics® Intragastric Balloon (BIB®) is used worldwide as a short-term treatment option in obese patients. A new frequency score was used to evaluate the influence of double consecutive BIB® treatment compared with single BIB® treatment followed by diet on four categories of EDNOS (grazing, emotional eating, sweet-eating and after-dinner grazing).
  
  
  METHODS
  A prospective study allocated 50 obese patients (age range 25-35, BMI range 40.0-44.9) into two groups: BIB® (6 months) followed by diet therapy (7 months; group A (N = 25)) and BIB® placement for 6 months followed by another BIB® for 6 months, with a 1-month interval between placement (group B (N = 25)). Baseline demographics were similar across both groups.
  
  
  RESULTS
  At the time of removal of the first BIB® device, EDNOS scores in both groups were not significantly different, but decreased significantly from baseline. By the end of the study, all EDNOS scores were significantly lower in patients undergoing consecutive BIB®, compared with single BIB® followed by diet therapy.
  
  
  CONCLUSIONS
  The placement of an intragastric balloon in obese patients allows for a reduction in the intensity of grazing, emotional eating, sweet-eating and after-dinner grazing. A more significant reduction in the EDNOS score was observed with two consecutive BIBs®.
authors.affiliation: Surgical Sciences Department, Medical School "Sapienza" University, Rome, Italy.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Genco
authors.forename: Roberta
authors.initials: R
authors.lastname: Maselli
authors.forename: Francesca
authors.initials: F
authors.lastname: Frangella
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Cipriano
authors.forename: Emanuela
authors.initials: E
authors.lastname: Paone
authors.forename: Valentina
authors.initials: V
authors.lastname: Meuti
authors.forename: Giovanni
authors.initials: G
authors.lastname: Baglio
authors.forename: Giovanni
authors.initials: G
authors.lastname: Casella
authors.forename: Michele
authors.initials: M
authors.lastname: Lorenzo
authors.forename: Nicola
authors.initials: N
authors.lastname: Basso
authors.forename: Redler
authors.initials: R
authors.lastname: Adriano
mesh_terms: D000328:Adult; D015992:Body Mass Index; D020878:Device Removal / Q000379:methods / Q000523:psychology; D004038:Diet, Reducing; D005247:Feeding Behavior / Q000523:psychology; D001068:Feeding and Eating Disorders / Q000453:epidemiology / Q000523:psychology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D015905:Gastric Balloon; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D009767:Obesity, Morbid / Q000453:epidemiology / Q000523:psychology / Q000601:surgery*; D015995:Prevalence; D011446:Prospective Studies; D016896:Treatment Outcome; D015431:Weight Loss