title: Cardiovascular disease and spinal cord injury: results from a national population health survey.
abstract: OBJECTIVE
  To evaluate the association between cardiovascular disease (CVD) and spinal cord injury (SCI) in a large representative sample.
  
  
  METHODS
  Data were compiled from more than 60,000 individuals from the 2010 cycle of the cross-sectional Canadian Community Health Survey (CCHS). Multivariable logistic regression analysis was conducted to examine this relationship, adjusting for confounders and using probability weighting to account for the CCHS sampling method.
  
  
  RESULTS
  After adjusting for age and sex, SCI was associated with a significant increased odds of heart disease (adjusted odds ratio [OR] = 2.72, 95% confidence interval [CI] 1.94-3.82) and stroke (adjusted OR = 3.72, 95% CI 2.22-6.23).
  
  
  CONCLUSIONS
  These remarkably heightened odds highlight the exigent need for targeted interventions and prevention strategies addressing modifiable risk factors for CVD in individuals with SCI.
authors.affiliation: School of Population and Public Health, Faculty of Medicine, International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver Canada. craggj@interchange.ubc.ca
authors.forename: Jacquelyn J
authors.initials: JJ
authors.lastname: Cragg
authors.forename: Vanessa K
authors.initials: VK
authors.lastname: Noonan
authors.forename: Andrei
authors.initials: A
authors.lastname: Krassioukov
authors.forename: Jaimie
authors.initials: J
authors.lastname: Borisoff
mesh_terms: D000328:Adult; D000368:Aged; D002170:Canada / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D015984:Causality; D015897:Comorbidity; D005260:Female; D019538:Health Care Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D016016:Proportional Hazards Models; D012307:Risk Factors; D013119:Spinal Cord Injuries / Q000453:epidemiology*; D020521:Stroke