title: [Influence of bronchodilatation test on duration of forced expiratory tracheal noises in young men].
abstract: A diagnostic effect of evaluation of forced expiratory noises duration in revealing bronchial obstruction was shown previously. The objective is an analysis of response of forced expiratory noises duration to bronchodilatation test with beta2-agonist among homogeneous in age and gender group of healthy volunteers and bronchial asthma patients, which was treated as a model of variable bronchial obstruction, 260 young men (age of 16-25 years) were examined. It was shown that in bronchial asthma patients with spirometry confirmed bronchial obstruction dominated response of shortening forced expiratory noises duration. Furthermore the magnitude of shortening was significantly dependent on background bronchial obstruction severity. Absence of statistically significant response of forced expiratory noises duration dominated among healthy volunteers (nonsmokers as well as smokers) and bronchial asthma patients without spirometry confirmed bronchial obstruction. However shortening response was met significantly frequently in bronchial asthma patients relatively to healthy volunteers. High specificity (86%) of forced expiratory noises duration shortening response to beta2-agonist may be useful for diagnostics.
authors.forename: I A
authors.initials: IA
authors.lastname: Pochekutova
authors.forename: V I
authors.initials: VI
authors.lastname: Korenbaum
mesh_terms: D000293:Adolescent; D058666:Adrenergic beta-2 Receptor Agonists / Q000008:administration & dosage*; D000328:Adult; D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology*; D001993:Bronchodilator Agents / Q000008:administration & dosage*; D005540:Forced Expiratory Flow Rates; D006801:Humans; D008297:Male; D012135:Respiratory Sounds; D014132:Trachea / Q000503:physiopathology*
chemical_list: D058666:Adrenergic beta-2 Receptor Agonists; D001993:Bronchodilator Agents