title: CFD modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with CT.
abstract: The objective of this study is to find a correlation between the abdominal aortic aneurysm (AAA) geometric parameters, wall stress shear (WSS), abdominal flow patterns, intraluminal thrombus (ILT), and AAA arterial wall rupture using computational fluid dynamics (CFD). Real AAA 3D models were created by three-dimensional (3D) reconstruction of in vivo acquired computed tomography (CT) images from 5 patients. Based on 3D AAA models, high quality volume meshes were created using an optimal tetrahedral aspect ratio for the whole domain. In order to quantify the WSS and the recirculation inside the AAA, a 3D CFD using finite elements analysis was used. The CFD computation was performed assuming that the arterial wall is rigid and the blood is considered a homogeneous Newtonian fluid with a density of 1050 kg/m(3) and a kinematic viscosity of 4 × 10(-3) Pa·s. Parallelization procedures were used in order to increase the performance of the CFD calculations. A relation between AAA geometric parameters (asymmetry index ( β ), saccular index ( γ ), deformation diameter ratio ( χ ), and tortuosity index ( ε )) and hemodynamic loads was observed, and it could be used as a potential predictor of AAA arterial wall rupture and potential ILT formation.
authors.affiliation: Centre Internacional de Mètodes Numèrics en Enginyeria, Biomedical Engineering Department, Technical University of Catalonia, C/Gran Capità, s/n, 08034 Barcelona, Spain.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Soudah
authors.forename: E Y K
authors.initials: EY
authors.lastname: Ng
authors.forename: T H
authors.initials: TH
authors.lastname: Loong
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bordone
authors.forename: Uei
authors.initials: U
authors.lastname: Pua
authors.forename: Sriram
authors.initials: S
authors.lastname: Narayanan
mesh_terms: D000465:Algorithms; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D019295:Computational Biology; D003198:Computer Simulation; D020342:Finite Element Analysis; D006439:Hemodynamics; D006801:Humans; D057446:Hydrodynamics; D021621:Imaging, Three-Dimensional / Q000379:methods; D008297:Male; D008955:Models, Cardiovascular; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods; D013314:Stress, Mechanical; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data