title: [Persistence of the treatment of overactive bladderin Czech Republic].
abstract: BACKGROUND
  Overactive bladder is chronic disease with high prevalence rate (9-42%). This syndrome requires longterm therapy but the persistence of this treatment in comparison with other chronic diseases as diabetes, hypertension, osteoporosis etc. is low. Accorging many studies the persistence variability is high and could be influenced by regional circumstanses. We desided to analyze real situation in parasympatolytics persitance in two years period in Czech Republic based on registry of health insurance company.
  
  
  METHODS
  We analyzed data between 2009 and 2010 of all clients of health insurance company where they fullfil their prescribtion. We analyzed the persistence in one year period in different periods of the year and within one year.
  
  
  RESULTS
  In comparison of the same period between those two year there was a trend of increase of prescription but it was not significant: 1306(SD 56.3) vs 1410 (SD 68.1) - p = 0.056. Prescription of the treatment after one year was only 18.5%(min. 16.8 - max. 20.4, SD 1.56). Major drop-out was in first 3-month period where renewed their prescription only 25.9% of the patients.
  
  
  CONCLUSIONS
  This one of the first study analyzing the parasympatolytics prescription persistence based on registry of health insurence company. The persistence in Czech Republic was low but withing the range of international data. Those result should be used as a reference data for comparison of the effect of varius strategies influencing the overactive bladder treatment.
authors.affiliation: Gynekologicko-porodnická klinika VFN a 1. LF UK, Praha. kamil@svabik.cz
authors.forename: K
authors.initials: K
authors.lastname: Svabík
authors.forename: J
authors.initials: J
authors.lastname: Krhut
authors.forename: V
authors.initials: V
authors.lastname: Finsterle
authors.forename: A
authors.initials: A
authors.lastname: Martan
mesh_terms: D000368:Aged; D018153:Czech Republic / Q000453:epidemiology; D005260:Female; D006801:Humans; D007348:Insurance, Health; D008297:Male; D008875:Middle Aged; D012042:Registries; D012189:Retrospective Studies; D053201:Urinary Bladder, Overactive / Q000188:drug therapy* / Q000453:epidemiology*