title: Molecular diagnosis of maturity onset diabetes of the young in India.
abstract: Diabetes is highly prevalent in India and the proportion of younger patients developing diabetes is on the increase. Apart from the more universally known type 1 diabetes and obesity related type 2 diabetes, monogenic forms of diabetes are also suspected to be prevalent in many young diabetic patients. The identification of the genetic basis of the disease not only guides in therapeutic decision making, but also aids in genetic counselling and prognostication. Genetic testing may establish the occurrence and frequency of early diabetes in our population. This review attempts to explore the utilities and horizons of molecular genetics in the field of maturity onset diabetes of the young (MODY), which include the commoner forms of monogenic diabetes.
authors.affiliation: Department of Endocrinology, Diabetes and Metabolism, Christian Medical College Hospital, Vellore, India.
authors.forename: Veena V
authors.initials: VV
authors.lastname: Nair
authors.forename: Aaron
authors.initials: A
authors.lastname: Chapla
authors.forename: Nishanth
authors.initials: N
authors.lastname: Arulappan
authors.forename: Nihal
authors.initials: N
authors.lastname: Thomas
keywords: Consanguinity; epigenetics; maturity onset diabetes of the young; molecular diagnosis; monogenic diabetes; neonatal diabetes