title: Bound phytophenols from ready-to-eat cereals: comparison with other plant-based foods.
abstract: Whole-grain diets are linked to reduced risk of several chronic diseases (heart disease, cancer, diabetes, metabolic syndrome) and all-cause mortality. There is increasing evidence that these benefits are associated with the gut microbiota and that release of fibre-related phenolic metabolites in the gut is a contributing factor. Additional sources of these metabolites include fruits and vegetables, but the evidence for their protective effects is less well established. With respect to the availability of bound phytophenols, ready-to-eat cereals are compared with soft fruits (considered rich in antioxidants) and other commonly consumed fruits and vegetables. The results demonstrated that when compared with an equivalent serving of fruits or vegetables, a recommended portion of whole-grain cereals deliver substantially higher amounts of bound phytophenols, which are available for metabolism in the colon. The increased amount of these phenolic metabolites may, in part, explain the evidence for the protective effects of whole-grain cereals.
authors.affiliation: Natural Products Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen AB21 9SB, UK.
authors.forename: M
authors.initials: M
authors.lastname: Neacsu
authors.forename: J
authors.initials: J
authors.lastname: McMonagle
authors.forename: R J
authors.initials: RJ
authors.lastname: Fletcher
authors.forename: L
authors.initials: L
authors.lastname: Scobbie
authors.forename: G J
authors.initials: GJ
authors.lastname: Duncan
authors.forename: L
authors.initials: L
authors.lastname: Cantlay
authors.forename: B
authors.initials: B
authors.lastname: de Roos
authors.forename: G G
authors.initials: GG
authors.lastname: Duthie
authors.forename: W R
authors.initials: WR
authors.lastname: Russell
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism; D004043:Dietary Fiber / Q000032:analysis / Q000378:metabolism; D002523:Edible Grain / Q000737:chemistry* / Q000378:metabolism; D057140:Fast Foods / Q000032:analysis*; D005638:Fruit / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D019800:Phenol / Q000737:chemistry* / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry* / Q000378:metabolism; D014675:Vegetables / Q000737:chemistry* / Q000378:metabolism
chemical_list: D000975:Antioxidants; D004043:Dietary Fiber; D010936:Plant Extracts; D019800:Phenol
keywords: Dietary fibre; Gut microbiota; Phenolic metabolites; Phytochemicals; Whole-grain