title: Determinants of health-related quality of life in psoriasis patients in Malaysia.
abstract: Psoriasis is a chronic dermatological disorder that has a negative impact on quality of life (QoL). This hospital-based cross-sectional study determined factors associated with health-related QoL (HRQoL) impairment in adult psoriasis patients. HRQoL was assessed using the Dermatology Life Quality Index (DLQI). Disease severity was assessed using the Psoriasis Area and Severity Index (PASI). A total of 223 patients, aged 18 to 83 years, were recruited. For 67 (30%) patients, psoriasis had very large to extremely large effect on their life (DLQI score = 11-30). The median DLQI score was 7 (interquartile range = 7). Factors significantly associated with severe impact on HRQoL (DLQI ≥ 10) were disease severity, single status, working status, sports activities, nail dystrophy, exposed area involvement, itch, disturbed sleep, stress, and infection. The factor predictive of severe impact of psoriasis on HRQoL was disease severity. A holistic approach in the management, including psychosocial issues, is absolutely crucial for the optimal care of psoriasis patients.
authors.affiliation: MAHSA University, Kuala Lumpur, Malaysia wint2008@gmail.com.
authors.forename: Wint Wint Thu
authors.initials: WW
authors.lastname: Nyunt
authors.affiliation: University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Wah Yun
authors.initials: WY
authors.lastname: Low
authors.affiliation: University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Rokiah
authors.initials: R
authors.lastname: Ismail
authors.affiliation: University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Sargunan
authors.initials: S
authors.lastname: Sockalingam
authors.affiliation: MAHSA University, Kuala Lumpur, Malaysia.
authors.forename: Aung Ko Ko
authors.initials: AK
authors.lastname: Min
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008296:Malaysia; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000523:psychology*; D011788:Quality of Life; D012720:Severity of Illness Index; D055815:Young Adult
keywords: Dermatology Life Quality Index; Psoriasis Area and Severity Index; dermatology; quality of life; skin disorder