title: [Late-onset hypogonadism among old and middle-aged males in a rural community of Zhejiang Province].
abstract: OBJECTIVE
  To investigate the epidemiology of late-onset hypogonadism (LOH) in old and middle-aged males in the rural area of Southern China.
  
  
  METHODS
  Using the age-stratified sampling method, we conducted a questionnaire investigation on androgen deficiency in aging males (ADAM), aging male symptoms (AMS) and IIEF-5 among 996 males aged 40 -80 years in a rural community of Jiashan county, Zhejiang Province from April to October 2012. We also determined the concentrations of serum total testosterone (TT), serum sex hormone binding globulin (SHBG) and serum albumin (ALB), detected the levels of free testosterone (cFT) and bio-available testosterone (Bio-T) by Vermeulen formula, and measured the volumes of the prostate and testis by ultrasonography.
  
  
  RESULTS
  The mean age of the males was 56.22 +/- 8.82 years. The positive rates of LOH were 62.86% and 23.05% based on ADAM and AMS, respectively, and the incidence of erectile dysfunction (ED) was 68.83%. There were significant differences among different age groups in the levels of luteinizing hormone (LH), SHBG, cFT and Bio-T, but not in TT concentration.
  
  
  CONCLUSIONS
  Ours was the first survey on the epidemiology of LOH among old and middle-aged males in the rural area of China. The incidence of LOH in the rural community of Zhejiang Province was lower than that in the urban areas reported in other studies, but the positive rate of ED showed no significant difference.
authors.affiliation: Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, China. wumanrj@126.com
authors.forename: Min
authors.initials: M
authors.lastname: Wu
authors.forename: Jian-Hui
authors.initials: JH
authors.lastname: Li
authors.forename: Xiao-Hua
authors.initials: XH
authors.lastname: Yu
authors.forename: Guo-Qing
authors.initials: GQ
authors.lastname: Liang
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Liu
authors.forename: Yi-Ran
authors.initials: YR
authors.lastname: Huang
authors.forename: Ying-Hao
authors.initials: YH
authors.lastname: Sun
authors.forename: Zheng
authors.initials: Z
authors.lastname: Li
mesh_terms: D000328:Adult; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D002681:China / Q000453:epidemiology; D007172:Erectile Dysfunction / Q000453:epidemiology; D006801:Humans; D007006:Hypogonadism / Q000453:epidemiology*; D015994:Incidence; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D012424:Rural Population; D011795:Surveys and Questionnaires; D013739:Testosterone / Q000097:blood
chemical_list: D013739:Testosterone; D007986:Luteinizing Hormone