title: Chiral phosphoric acid-catalyzed oxidative kinetic resolution of indolines based on transfer hydrogenation to imines.
abstract: The oxidative kinetic resolution of 2-substituted indoline derivatives was achieved by hydrogen transfer to imines by means of a chiral phosphoric acid catalyst. The oxidative kinetic resolution was applicable to racemic alkyl- or aryl-substituted indolines, and the remaining indolines were obtained in good yields with excellent enantioselectivities.
authors.affiliation: Department of Chemistry, Faculty of Science, Gakushuin University, 1-5-1 Mejiro, Toshima-ku, Tokyo 171-8588, Japan.
authors.forename: Kodai
authors.initials: K
authors.lastname: Saito
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Shibata
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yamanaka
authors.forename: Takahiko
authors.initials: T
authors.lastname: Akiyama
mesh_terms: D002384:Catalysis; D006865:Hydrogenation; D007097:Imines / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D007700:Kinetics; D010084:Oxidation-Reduction; D010756:Phosphoric Acids / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007097:Imines; D007211:Indoles; D010756:Phosphoric Acids; C057812:indoline; C030242:phosphoric acid