title: Topiramate induced sudden loss of vision.
abstract: The case of a 20 year old female presenting with overnight acute loss of vision is reported. The patient was recently started on topiramate (Hitop) for her recurrent migraine and developed sudden loss of vision due to acute myopia. Topiramate was discontinued and the patient's vision returned to normal. Delayed and incorrect treatment may result in permanent vision loss, secondary to angle closure glaucoma; therefore it is imperative that prescribing physicians are aware of this rare but serious ocular emergency.
authors.affiliation: Department of Ophthalmology and Retinal Surgery, Shahzad Eye Hospital, Gulshan-e-Iqbal, Karachi, Pakistan.
authors.forename: Mehreen
authors.initials: M
authors.lastname: Baloch
authors.forename: Muhammad Abdul Rehman
authors.initials: MA
authors.lastname: Siddiqui
mesh_terms: D004487:Edema / Q000139:chemically induced; D005260:Female; D005632:Fructose / Q000009:adverse effects / Q000031:analogs & derivatives*; D015812:Glaucoma, Angle-Closure / Q000139:chemically induced*; D006801:Humans; D009216:Myopia / Q000139:chemically induced*; D018696:Neuroprotective Agents / Q000009:adverse effects*; D000077236:Topiramate; D055815:Young Adult
chemical_list: D018696:Neuroprotective Agents; D000077236:Topiramate; D005632:Fructose