title: Epidemiological evaluation of laryngeal cancer incidence in Kazakhstan for the years 1999-2009.
abstract: The purpose was to provide a descriptive epidemiological assessment of the incidence of cancer of the larynx in Kazakhstan and spatial evaluation with gender characteristics. This retrospective study covered all new cases of laryngeal cancer in 11 years (1999-2009). The total number was 4,967 cases, 4,535 (91.3%) in males and 432 (8.7%) in women, with a ratio of 10.5:1. The higher incidence in men compared to women was evident in all age groups, the differences being statistically significant (p<0.05). At the same time revealed a unimodal growth with age, peaking at 70 years and older both sexes. In the dynamics, incidence rates of laryngeal cancer demonstrated a tendency to decrease, in women (T=-6.7%) this being more pronounced than in men (T=-3.3%). Levels were determined to produce cartograms of cancer of the larynx for male and female populations, clear geographical variation being evidenced. The data are discussed with reference to possible risk factors.
authors.affiliation: Central Asia Cancer Institute, Kazakhstan. nurbek_igisinov@mail.ru
authors.forename: Nurbek
authors.initials: N
authors.lastname: Igissinov
authors.forename: Vera
authors.initials: V
authors.lastname: Zatoskikh
authors.forename: Malcolm Anthony
authors.initials: MA
authors.lastname: Moore
authors.forename: Saginbek
authors.initials: S
authors.lastname: Igissinov
authors.forename: Rais
authors.initials: R
authors.lastname: Toulebaeyev
authors.forename: Meruert
authors.initials: M
authors.lastname: Mustafina
authors.forename: Saule
authors.initials: S
authors.lastname: Valieva
authors.forename: Gulmira
authors.initials: G
authors.lastname: Aldiyarova
authors.forename: Zhanar
authors.initials: Z
authors.lastname: Bukeyeva
authors.forename: Anatoly
authors.initials: A
authors.lastname: Venglovskiy
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007623:Kazakhstan / Q000453:epidemiology; D007822:Laryngeal Neoplasms / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012042:Registries / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors