title: The correlations of disease activity, socioeconomic status, quality of life, and depression/anxiety in Chinese patients with systemic lupus erythematosus.
abstract: The prevalence of psychological problems is frequent in systemic lupus erythematosus (SLE) patients and appears to be increasing. The current study investigated the relationship among disease parameters, quality of life, and the psychological status in Chinese patients with SLE. A self-report survey design was administered to 170 SLE patients and 210 healthy individuals using the Self-Rating Anxiety Scale, the Self-Rating Depression Scale, and the Short Form 36 health survey (SF-36). Our results showed that 20.3% SLE patients had anxiety, and 32.9% had depression, which were significantly higher than the control group (7.1%, 14.3%, resp.). And there were significant correlations among socioeconomic status (SES), disease activity, and anxiety/depression in SLE patients. Meanwhile, SF-36 analysis results revealed that VT, PF, and RP scales were the most powerful predictors of anxiety of SLE patients, and SLEDAI, VT, PF, SF, and RE domains were significantly accounted for anxiety. In summary, there were significant relationships among disease parameters, quality of life, and anxiety/depression in Chinese SLE patients. Therefore, it is necessary to have psychiatric and psychological evaluations and formulate an integrated approach for managing mental health in Chinese lupus patients, especially those who have high disease activity, low SES, and poor quality of life.
authors.affiliation: Department of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, China.
authors.forename: Biyu
authors.initials: B
authors.lastname: Shen
authors.forename: Wei
authors.initials: W
authors.lastname: Tan
authors.forename: Guijuan
authors.initials: G
authors.lastname: Feng
authors.forename: Yan
authors.initials: Y
authors.lastname: He
authors.forename: Jinwei
authors.initials: J
authors.lastname: Liu
authors.forename: Weijun
authors.initials: W
authors.lastname: Chen
authors.forename: Xiaoqin
authors.initials: X
authors.lastname: Huang
authors.forename: Zhanyun
authors.initials: Z
authors.lastname: Da
authors.forename: Xujuan
authors.initials: X
authors.lastname: Xu
authors.forename: Hong
authors.initials: H
authors.lastname: Liu
authors.forename: Zhifeng
authors.initials: Z
authors.lastname: Gu
mesh_terms: D000328:Adult; D001007:Anxiety / Q000150:complications / Q000208:ethnology / Q000503:physiopathology / Q000523:psychology*; D044466:Asian People; D016022:Case-Control Studies; D003863:Depression / Q000150:complications / Q000208:ethnology / Q000503:physiopathology / Q000523:psychology*; D005260:Female; D006306:Health Surveys; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000208:ethnology / Q000503:physiopathology / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D012720:Severity of Illness Index; D012923:Social Class