title: Dysembryoplastic neuroepithelial tumor with rapid recurrence of pilocytic astrocytoma component.
abstract: Dysembryoplastic neuroepithelial tumor (DNT) rarely has aggressive behavior with recurrence. The authors describe a case of DNT with rapid re-growth and features of pilocytic astrocytoma. A 19-year-old girl presented with a 3-year history of complex partial seizure, which was presumably because of DNT located in the left parietal lobe. The tumor was resected, although a tiny residual lesion with cystic space enlarged with ring enhancement identified on MRI 14 days after surgery resulted in re-excision. The recurrent tumor was eventually proved to be predominantly composed of pilocytic astrocytoma. DNT is known to recur only rarely as a tumor with morphologically different components, and no cases of recurrent DNT with rapidly-growing pilocytic astrocytoma have hitherto been reported in the literature. This phenomenon may be histological "replacement" at recurrence.
authors.affiliation: Department of Neurosurgery, Kyoto University Graduate of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
authors.forename: Yasuhide
authors.initials: Y
authors.lastname: Takeuchi
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Arakawa
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Mikami
authors.forename: Riki
authors.initials: R
authors.lastname: Matsumoto
authors.forename: Susumu
authors.initials: S
authors.lastname: Miyamoto
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D004828:Epilepsies, Partial / Q000209:etiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary; D018302:Neoplasms, Neuroepithelial / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D010296:Parietal Lobe; D012086:Reoperation; D055815:Young Adult