title: Multidrug-resistant Pseudomonas aeruginosa: a case of pyelonephritis and herbal therapy.
abstract: Multidrug-resistant Pseudomonas aeruginosa, which was only susceptible to colistin, was isolated from the urine of a patient with pyelonephritis. The isolates were confirmed as class A Extended-spectrum-β-lactamase-producing isolates. A blaBEL allele was detected by multiplex polymerase chain reaction. The organisms were identified as ST235, serotype O11. Chinese herbal decoction was orally administered. The patient returned 8 days later with relief of symptoms. No P. aeruginosa was isolated from two urine samples taken after 1 week and 2 weeks from the end of herbal therapy. The case supports the notion that these Chinese herbs are useful in treating pyelonephritis caused by multidrug-resistant P. aeruginosa. Chinese herbal medicine has allowed another choice of treatment.
authors.affiliation: Department of Nephrology, The First Affiliated Hospital to Changchun University of Chinese Medicine , Changchun City, Jilin Province, China .
authors.forename: YanQing
authors.initials: Y
authors.lastname: Tong
authors.forename: Min
authors.initials: M
authors.lastname: Sun
authors.forename: ChuFeng
authors.initials: C
authors.lastname: Wang
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006801:Humans; D010936:Plant Extracts / Q000627:therapeutic use*; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000302:isolation & purification; D011704:Pyelonephritis / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts