title: Mid-term outcomes in HIV-positive patients after primary total hip or knee arthroplasty.
abstract: We hypothesized that infection rates following total joint arthroplasty (TJA) in those with the human immunodeficiency virus (HIV) without hemophilia or drug use would be similar to rates in HIV-negative patients. Records at an urban HIV referral hospital were searched for patients who underwent primary total hip and knee arthroplasty from 2003 to 2010. The primary outcome was revision for infection. 372 HIV-negative and 22 HIV-positive TJA patients met inclusion criteria. The HIV-positive group had more deep infections than the HIV-negative group (9.1% v 2.2%, P=0.102). There were no infections in those with AIDS-defining CD4 counts. Those with HIV may have a higher risk of developing a deep infection. A low CD4 count is not an absolute contraindication to TJA in HIV positive patients.
authors.affiliation: Department of Orthopaedic Surgery, Hennepin County Medical Center, Minneapolis, Minnesota.
authors.forename: Carol A
authors.initials: CA
authors.lastname: Lin
authors.affiliation: San Francisco VA Medical Center, San Francisco, California.
authors.forename: Steven
authors.initials: S
authors.lastname: Takemoto
authors.affiliation: Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California; Department of Orthopaedic Surgery, San Francisco General Hospital, San Francisco, California.
authors.forename: Utku
authors.initials: U
authors.lastname: Kandemir
authors.affiliation: San Francisco VA Medical Center, San Francisco, California; Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California.
authors.forename: Alfred C
authors.initials: AC
authors.lastname: Kuo
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D015897:Comorbidity; D005260:Female; D015658:HIV Infections / Q000453:epidemiology*; D006785:Hospitals, University; D006786:Hospitals, Urban; D006801:Humans; D007592:Joint Diseases / Q000453:epidemiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000453:epidemiology* / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000209:etiology; D016896:Treatment Outcome
keywords: HAART; HIV/AIDS; THA; TKA