title: Late-onset bleb-related endophthalmitis caused by Streptococcus pseudopneumoniae.
abstract: We report our findings in a 63-year-old male who developed late-onset bleb-related endophthalmitis. The patient had undergone glaucoma surgery 46 years earlier, and had a thin-walled cystic bleb prior to the endophthalmitis in his right eye. He underwent immediate vitrectomy with intravitreal injections of ceftazidime and vancomycin. After surgery, he was given topical 0.5 % moxifloxacin and 1 % vancomycin, intravenous doripenem, and oral minocycline. Culture of the vitreous specimen identified Streptococcus pseudopneumoniae by 16S rRNA sequence analysis, by optochin susceptibility test, and by bile solubility test. Our findings indicate that S. pseudopneumoniae can be isolated from a late-onset bleb-related endophthalmitis and that molecular analysis and phenotypic testing can be accurate methods to identify S. pseudopneumoniae.
authors.affiliation: Department of Ophthalmology, Gifu Municipal Hospital, 7-1 Kashima-cho, Gifu, 500-8513, Japan, hkawa-gif@umin.ac.jp.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kawakami
authors.forename: Yuko
authors.initials: Y
authors.lastname: Nakane
authors.forename: Hiroko
authors.initials: H
authors.lastname: Inuzuka
authors.forename: Tominori
authors.initials: T
authors.lastname: Fukagawa
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Muto
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Mochizuki
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Ohkusu
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Suematsu
authors.forename: Yuka
authors.initials: Y
authors.lastname: Yamagishi
authors.forename: Hiroshige
authors.initials: H
authors.lastname: Mikamo
mesh_terms: D017668:Age of Onset; D001768:Blister / Q000382:microbiology*; D009877:Endophthalmitis / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013290:Streptococcal Infections / Q000382:microbiology*; D013291:Streptococcus / Q000302:isolation & purification*