title: Advances in pediatric oncology MRI.
abstract: Refined stratification of disease is thought to result in better survival from childhood malignant disease while minimizing the adverse effects of anticancer therapies. There is a potential for magnetic resonance imaging (MRI) to contribute to such stratification by improved tissue characterization, anatomical depiction, staging, and assessment of early treatment response. Recent advances in pediatric MRI outside the central nervous system (CNS) are reviewed in this context. The focus is on new applications for conventional MRI and on clinical implementation of tissue-specific and quantitative techniques. This area is largely unexplored, and potential directions for research are indicated.
authors.affiliation: Radiology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London, UK.
authors.forename: Øystein E
authors.initials: ØE
authors.lastname: Olsen
mesh_terms: D002648:Child; D003287:Contrast Media; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D009367:Neoplasm Staging; D009369:Neoplasms / Q000175:diagnosis* / Q000473:pathology; D010372:Pediatrics / Q000379:methods*
chemical_list: D003287:Contrast Media; C073590:gadolinium ethoxybenzyl DTPA; D019786:Gadolinium DTPA
keywords: MR diffusion/perfusion; magnetic resonance imaging (MRI); neoplasms – primary; pediatrics; staging