title: Molecular subtyping of Treponema pallidum in Paris, France.
abstract: Two major Treponema pallidum subtypes, 14 d/g and 14 d/f, were identified in a population of 119 patients with syphilis in Paris, France, characterized by a high proportion of men who have sex with men. A new subtype named 11 q/j was characterized, and a reinfection case was determined in 1 patient having consecuitve syphilis infection at 19-month interval.
authors.affiliation: Laboratoire de Recherche en Dermatologie, EA 1833, Centre National de Référence Syphilis, Faculté de Médecine, Université Sorbonne Paris Descartes, Paris, France.
authors.forename: Philippe Alain
authors.initials: PA
authors.lastname: Grange
authors.forename: Caroline
authors.initials: C
authors.lastname: Allix-Beguec
authors.forename: Johan
authors.initials: J
authors.lastname: Chanal
authors.forename: Nadjet
authors.initials: N
authors.lastname: Benhaddou
authors.forename: Philippe
authors.initials: P
authors.lastname: Gerhardt
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Morini
authors.forename: Jean
authors.initials: J
authors.lastname: Deleuze
authors.forename: François
authors.initials: F
authors.lastname: Lassau
authors.forename: Michel
authors.initials: M
authors.lastname: Janier
authors.forename: Nicolas
authors.initials: N
authors.lastname: Dupin
mesh_terms: D000293:Adolescent; D000328:Adult; D060085:Coinfection; D004256:DNA Polymerase I / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000453:epidemiology; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D058889:Molecular Typing; D010297:Paris / Q000453:epidemiology; D016133:Polymerase Chain Reaction; D018571:Sentinel Surveillance; D013048:Specimen Handling; D013587:Syphilis / Q000453:epidemiology / Q000382:microbiology*; D014210:Treponema pallidum / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D004269:DNA, Bacterial; D004256:DNA Polymerase I