title: Incidence of lower urinary tract symptoms in a population-based study of men and women.
abstract: OBJECTIVE
  To report the incidence of lower urinary tract symptoms (LUTS) in a racially and ethnically and age-diverse U.S. population-based sample of men and women.
  
  
  METHODS
  We conducted a prospective cohort study with 5 years of follow-up. A stratified 2-stage cluster random sampling method was used to recruit 5502 Boston residents aged 30-79 years of black, Hispanic, or white race or ethnicity. Of these, 4144 (1610 men and 2534 women) completed the follow-up protocol. The American Urological Association Symptom Index was used to define moderate-to-severe LUTS.
  
  
  RESULTS
  Of the 3301 men and women with no or mild LUTS at baseline, the 5-year incidence of moderate-to-severe LUTS (American Urological Association Symptom Index ≥8) was 11.4% overall and was higher for women than for men (13.9% vs 8.5%, P = .02). Although the incidence increased with age (P <.001), it had a plateau among women aged 50-70 years and then doubled to 35.0% among women aged ≥70 years. White men had a distinctly lower incidence (7%) than all other sex and race subgroups (13%).
  
  
  CONCLUSIONS
  Approximately 1 in 10 adults had newly developed LUTS at 5 years follow-up of in our study, with differences by sex and race or ethnicity, indicating a greater occurrence of urologic problems among black and Hispanic participants and women.
authors.affiliation: New England Research Institutes, Watertown, MA, USA. nmaserejian@neriscience.com
authors.forename: Nancy N
authors.initials: NN
authors.lastname: Maserejian
authors.forename: Shan
authors.initials: S
authors.lastname: Chen
authors.forename: Gretchen R
authors.initials: GR
authors.lastname: Chiu
authors.forename: Carrie G
authors.initials: CG
authors.lastname: Wager
authors.forename: Varant
authors.initials: V
authors.lastname: Kupelian
authors.forename: Andre B
authors.initials: AB
authors.lastname: Araujo
authors.forename: John B
authors.initials: JB
authors.lastname: McKinlay
mesh_terms: D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data*; D000367:Age Factors; D000368:Aged; D001900:Boston / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006630:Hispanic or Latino / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D059411:Lower Urinary Tract Symptoms / Q000453:epidemiology* / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012720:Severity of Illness Index; D012737:Sex Factors; D044465:White People / Q000706:statistics & numerical data*