title: Gold nanoparticle-sensitized quartz crystal microbalance sensor for rapid and highly selective determination of Cu(II) ions.
abstract: A novel quartz crystal microbalance (QCM) sensor for rapid, highly selective and sensitive detection of copper ions was developed. As a signal amplifier, gold nanoparticles (Au NPs) were self-assembled onto the surface of the sensor. A simple dip-and-dry method enabled the whole detection procedure to be accomplished within 20 min. High selectivity of the sensor towards copper ions is demonstrated by both individual and coexisting assays with interference ions. This gold nanoparticle mediated amplification allowed a detection limit down to 3.1 μM. Together with good repeatability and regeneration, the QCM sensor was also applied to the analysis of copper contamination in drinking water. This work provides a flexible method for fabricating QCM sensors for the analysis of important small molecules in environmental and biological samples.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Zhongguancun North First Street 2, 100190, Beijing, PR China.
authors.forename: Yulong
authors.initials: Y
authors.lastname: Jin
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Huang
authors.forename: Guoquan
authors.initials: G
authors.lastname: Liu
authors.forename: Rui
authors.initials: R
authors.lastname: Zhao
mesh_terms: D015097:3-Mercaptopropionic Acid / Q000737:chemistry; D003300:Copper / Q000032:analysis*; D060766:Drinking Water / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D008024:Ligands; D053768:Metal Nanoparticles / Q000737:chemistry*; D058525:Quartz Crystal Microbalance Techniques / Q000379:methods*; D013499:Surface Properties; D013997:Time Factors
chemical_list: D060766:Drinking Water; D008024:Ligands; D006046:Gold; D003300:Copper; D015097:3-Mercaptopropionic Acid