title: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome.
abstract: Drug rash with eosinophilia and systemic symptoms syndrome is a severe idiosyncratic drug reaction with a long latency period. It has been described using many terms; however, drug rash with eosinophilia and systemic symptoms syndrome appears to be the most appropriate. This syndrome causes a diverse array of clinical symptoms, anywhere from 2 to 8 weeks after initiating the offending drug. Standardized criteria for the diagnosis have been developed; however, their utility remains to be validated. Unfortunately, the management of drug rash with eosinophilia and systemic symptoms syndrome is not well supported by strong evidence-based data.
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.
authors.forename: Sonal
authors.initials: S
authors.lastname: Choudhary
authors.forename: Michael
authors.initials: M
authors.lastname: McLeod
authors.forename: Daniele
authors.initials: D
authors.lastname: Torchia
authors.forename: Paolo
authors.initials: P
authors.lastname: Romanelli