title: Metal-free oxidative hydroxyalkylarylation of activated alkenes by direct sp3 C-H functionalization of alcohols.
abstract: A metal-free tandem radical addition/cyclization reaction of activated alkenes and alcohols has been developed. The process provides an efficient and atom economical access to various valuable hydroxyl-containing oxindoles through the direct sp(3) C-H functionalization of alcohols.
authors.affiliation: Department of Chemistry, School of Science and MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, Xi'an Jiaotong University, Xi'an 710049, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Meng
authors.forename: Li-Na
authors.initials: LN
authors.lastname: Guo
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
authors.forename: Xin-Hua
authors.initials: XH
authors.lastname: Duan
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D000078183:Oxindoles
chemical_list: D000438:Alcohols; D000475:Alkenes; D007211:Indoles; D000078183:Oxindoles; C022960:2-oxindole