title: Eumycetoma of the foot caused by Exophiala jeanselmei in a Guinean woman.
abstract: Eumycetomas are chronic infectious entities characterized by presence of mycotic grains in (sub-)cutaneous tissues, after accidental inoculation of an exogenous filamentous fungus in the skin. The lesions evolve towards painless pseudotumor of the soft parts. We report the original case of a Guinean woman exhibiting eumycetoma of the right foot. Both laboratory tests identified a dematiaceous fungus, Exophiala jeanselmei, as the responsible infectious agent. A medical treatment with voriconazole alone was sufficient to notice a substantial clinical improvement. This finding is unusual as E. jeanselmei is uncommon in Guinea-Conakry, and as optimal treatment rather associate antifungal azoles and surgical excision.
authors.affiliation: Service de parasitologie-mycologie--médecine tropicale, CHU de Tours, Tours cedex 09, France.
authors.forename: G
authors.initials: G
authors.lastname: Desoubeaux
authors.forename: A
authors.initials: A
authors.lastname: Millon
authors.forename: B
authors.initials: B
authors.lastname: Freychet
authors.forename: A
authors.initials: A
authors.lastname: de Muret
authors.forename: D
authors.initials: D
authors.lastname: Garcia-Hermoso
authors.forename: E
authors.initials: E
authors.lastname: Bailly
authors.forename: P
authors.initials: P
authors.lastname: Rosset
authors.forename: J
authors.initials: J
authors.lastname: Chandenier
authors.forename: L
authors.initials: L
authors.lastname: Bernard
mesh_terms: D000328:Adult; D005093:Exophiala / Q000302:isolation & purification / Q000502:physiology*; D005260:Female; D005534:Foot Diseases / Q000000981:diagnostic imaging / Q000382:microbiology*; D016701:Guinea; D006801:Humans; D008271:Mycetoma / Q000000981:diagnostic imaging / Q000382:microbiology*; D014463:Ultrasonography
keywords: Champignon dématié; Dematiaceous fungus; Eumycetomas; Eumycétomes; Exophiala jeanselmei; Exérèse chirurgicale; Grains fongique; Mycotic grains; Surgical excision; Voriconazole