title: Silver cations fold i-motif at neutral pH.
abstract: i-Motif DNA structures have previously been utilised for many different nanotechnological applications, but all have used acidic conditions to fold the DNA. Herein we describe the use of silver cations to fold an i-motif forming DNA sequence at physiological pH. Subsequent DNA unfolding can be achieved by chelation with cysteine.
authors.affiliation: School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK.
authors.forename: Henry A
authors.initials: HA
authors.lastname: Day
authors.forename: Camille
authors.initials: C
authors.lastname: Huguin
authors.forename: Zoë A E
authors.initials: ZA
authors.lastname: Waller
mesh_terms: D002412:Cations / Q000737:chemistry; D002942:Circular Dichroism; D003545:Cysteine / Q000737:chemistry; D004247:DNA / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D009690:Nucleic Acid Conformation; D012834:Silver / Q000737:chemistry*
chemical_list: D002412:Cations; D012834:Silver; D004247:DNA; D003545:Cysteine