title: [Padma 28 in cytostatic-induced dysesthesia and edema of the hands--a case from practice].
abstract: BACKGROUND
  The herbal complex formula Padma 28 is mostly used in circulation-induced paresthesia, in feelings of heaviness and tension in the legs and arms, and in numbness of the hands and feet.
  
  
  METHODS
  In the case presented here of a patient with breast cancer, status after full mastectomy, severe cytostatic-induced edema, and dysesthesia occurred on both hands, which made simple, daily tasks impossible. Treatment with high doses of vitamin B6 was unsuccessful. Padma 28 was given under the rationale to improve the microcirculation and thus to protect the delicate nerve endings. Despite ongoing chemotherapy, this treatment led to an improvement of the dysesthesia after 2 weeks, and after 5 weeks, the sensory disturbances and edema of the hands had completely disappeared.
  
  
  CONCLUSIONS
  Padma 28 seems therefore suitable for adjuvant use in paresthesia and swelling caused by cytotoxic drugs during chemotherapy.
authors.affiliation: Allgemeine Innere Medizin FMH, Institut für Naturheilkunde, UniversitätsSpital Zürich, Schweiz.
authors.forename: Bettina
authors.initials: B
authors.lastname: Kneip
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D044584:Carcinoma, Ductal / Q000188:drug therapy* / Q000473:pathology; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D000077143:Docetaxel; D005260:Female; D005500:Follow-Up Studies; D006225:Hand / Q000098:blood supply / Q000294:innervation*; D006801:Humans; D008197:Lymph Node Excision; D008209:Lymphedema / Q000139:chemically induced* / Q000188:drug therapy*; D008408:Mastectomy; D038861:Medicine, Tibetan Traditional; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D010292:Paresthesia / Q000139:chemically induced* / Q000188:drug therapy*; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D011984:Sensory Receptor Cells / Q000187:drug effects; D043823:Taxoids / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D010936:Plant Extracts; D043823:Taxoids; C066069:Padma 28; D000077143:Docetaxel