title: Genetically engineered peptides for inorganics: study of an unconstrained bacterial display technology and bulk aluminum alloy.
abstract: The first-ever peptide biomaterial discovery using an unconstrained engineered bacterial display technology is reported. Using this approach, we have developed genetically engineered peptide binders for a bulk aluminum alloy and use molecular dynamics simulation of peptide conformational fluctuations to demonstrate sequence-dependent, structure-function relationships for metal and metal oxide interactions.
authors.affiliation: U.S. Army Research Laboratory, RDRL-SEE-B, 2800 Powder Mill Road, Adelphi, MD 20783, USA.
authors.forename: Bryn L
authors.initials: BL
authors.lastname: Adams
authors.forename: Amethist S
authors.initials: AS
authors.lastname: Finch
authors.forename: Margaret M
authors.initials: MM
authors.lastname: Hurley
authors.forename: Deborah A
authors.initials: DA
authors.lastname: Sarkes
authors.forename: Dimitra N
authors.initials: DN
authors.lastname: Stratis-Cullum
mesh_terms: D000497:Alloys / Q000737:chemistry*; D000535:Aluminum / Q000737:chemistry*; D004926:Escherichia coli / Q000235:genetics*; D005818:Genetic Engineering; D019151:Peptide Library; D010455:Peptides / Q000737:chemistry / Q000235:genetics*; D013499:Surface Properties
chemical_list: D000497:Alloys; D019151:Peptide Library; D010455:Peptides; D000535:Aluminum
keywords: GEPI; biomineralization; biopanning; molecular dynamics; peptide display; solid-binding peptide