title: [Granulomatosis with polyangiitis (previously Wegener's granulomatosis) mimicking malingering].
abstract: BACKGROUND
  ANCA vasculitis may involve the skin and develop slowly without specific histology, and without autoantibodies.
  
  
  METHODS
  We report a 50-year-old woman who experienced bilateral mastectomy because of ulcero-necrotic, non-specific inflammatory cutaneous lesions of the breasts. First considered by others as a malinger patient, she developed oto-neurological lesions leading to the diagnosis of Wegener's granulomatosis. Five years later, specific antibodies of the disease were present.
  
  
  CONCLUSIONS
  Cutaneous involvement by ANCA vasculitis can be isolated for a long time. Physicians must have a high degree of suspicion to avoid diagnostic delay of ANCA vasculitis.
authors.affiliation: Service de médecine interne, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex, France.
authors.forename: N
authors.initials: N
authors.lastname: Ene
authors.affiliation: Service de médecine interne, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex, France. Electronic address: pauline.belenotti@ap-hm.fr.
authors.forename: P
authors.initials: P
authors.lastname: Bélénotti
authors.affiliation: Service de médecine interne, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Benyamine
authors.affiliation: Service de médecine interne, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex, France.
authors.forename: S
authors.initials: S
authors.lastname: Sovaila
authors.affiliation: Service de médecine interne, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex, France.
authors.forename: M H
authors.initials: MH
authors.lastname: Ben Sahla Talet
authors.affiliation: Service de cardiologie, médecine interne, CHU Brabois Médecine J, avenue de Bourgogne, 54500 Vandœuvre-lès-Nancy, France.
authors.forename: P
authors.initials: P
authors.lastname: Kaminsky
authors.affiliation: Service de médecine interne, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex, France.
authors.forename: J
authors.initials: J
authors.lastname: Serratrice
authors.affiliation: Service de médecine interne, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille cedex, France.
authors.forename: P-J
authors.initials: PJ
authors.lastname: Weiller
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D001940:Breast / Q000473:pathology; D057210:Delayed Diagnosis; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D014890:Granulomatosis with Polyangiitis / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007155:Immunologic Factors / Q000097:blood*; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D008306:Malingering; D008408:Mastectomy; D008875:Middle Aged; D017211:Treatment Failure; D016896:Treatment Outcome
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D015415:Biomarkers; D005938:Glucocorticoids; D007155:Immunologic Factors; D007166:Immunosuppressive Agents
keywords: Anti-neutrophil cytoplasmic antibody; Anticorps anti-cytoplasme des polynucléaires; Breast tumor; Granulomatose avec polyangéite; Granulomatosis with polyangiitis; Maladie de Wegener; Tumeur mammaire; Wegener granulomatosis