title: Fabrication and characterization of magnetic microrobots for three-dimensional cell culture and targeted transportation.
abstract: Magnetically manipulated microrobots are demonstrated for targeted cell transportation. Full three-dimensional (3D) porous structures are fabricated with an SU-8 photoresist using a 3D laser lithography system. Nickel and titanium are deposited as a magnetic material and biocompatible material, respectively. The fabricated microrobots are controlled in the fluid by external magnetic fields. Human embryonic kidney 239 (HEK 239) cells are cultivated in the microrobot to show the possibility for targeted cell transportation.
authors.affiliation: Robotics Engineering Department, Daegu Gyeongbuk Institute of Science and Technology (DGIST), 711-873, Daegu, South Korea; Brain Science Department, Daegu Gyeongbuk Institute of Science and Technology (DGIST), 711-873, Daegu, South Korea.
authors.forename: Sangwon
authors.initials: S
authors.lastname: Kim
authors.forename: Famin
authors.initials: F
authors.lastname: Qiu
authors.forename: Samhwan
authors.initials: S
authors.lastname: Kim
authors.forename: Ali
authors.initials: A
authors.lastname: Ghanbari
authors.forename: Cheil
authors.initials: C
authors.lastname: Moon
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Bradley J
authors.initials: BJ
authors.lastname: Nelson
authors.forename: Hongsoo
authors.initials: H
authors.lastname: Choi
mesh_terms: D018929:Cell Culture Techniques / Q000379:methods*; D016503:Drug Delivery Systems / Q000379:methods*; D005240:Feasibility Studies; D057809:HEK293 Cells; D006801:Humans; D060328:Magnetic Phenomena; D055616:Microtechnology / Q000379:methods*; D011108:Polymers / Q000737:chemistry; D016062:Porosity; D012371:Robotics / Q000379:methods*
chemical_list: D011108:Polymers
keywords: magnetic manipulation; microrobots; targeted cell transportation; three-dimensional cell culture