title: Temporal dynamics of recovery from extinction shortly after extinction acquisition.
abstract: Evidence suggests that extinction is new learning. Memory acquisition involves both short-term memory (STM) and long-term memory (LTM) components; however, few studies have examined early phases of extinction retention. Retention of auditory fear extinction was examined at various time points. Shortly (1-4 h) after extinction acquisition spontaneous recovery was high compared to that after longer delays (8-24 h). Recall of a consolidated extinction trace was also impaired if it was preceded 1 h by extinction of a novel CS; propranolol did not attenuate this effect. These results suggest poor extinction retention reflects a retrieval impairment caused by the aversive experience of extinction training.
authors.affiliation: Department of Psychology, McGill University, Montreal, Quebec, Canada H3A1B1. georgina.archbold@mail.mcgill.ca
authors.forename: Georgina E
authors.initials: GE
authors.lastname: Archbold
authors.forename: Nick
authors.initials: N
authors.lastname: Dobbek
authors.forename: Karim
authors.initials: K
authors.lastname: Nader
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D005108:Extinction, Psychological / Q000187:drug effects / Q000502:physiology*; D005239:Fear / Q000187:drug effects / Q000502:physiology*; D008297:Male; D008568:Memory / Q000187:drug effects / Q000502:physiology*; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol