title: Clinical and biological aspects of rotator cuff tears.
abstract: Rotator cuff tears are common and are a frequent source of shoulder pain and disability. A wide variation in the prevalence of rotator cuff tears has been reported. The etiology of rotator cuff tear remains multifactorial and attempts to unify intrinsic and extrinsic theories tried to explain the etiopathogenesis of rotator cuff tears. Knowledge of the etiopathogenesis of rotator cuff tears is important to improve our therapies, surgical techniques and promote tendon repair. Several strategies have been proposed to enhance tendon healing and recently research has focused on regenerative therapies, such as Growth Factors (GFs) and Plasma Rich Platelet (PRP), with high expectations of success.
authors.affiliation: Department of Orthopaedic and Traumatology, University of Rome "Tor Vergata", School of Medicine, Rome, Italy.
authors.forename: Alessio Giai
authors.initials: AG
authors.lastname: Via
authors.forename: Mauro
authors.initials: M
authors.lastname: De Cupis
authors.forename: Marco
authors.initials: M
authors.lastname: Spoliti
authors.forename: Francesco
authors.initials: F
authors.lastname: Oliva
keywords: growth factors; platelet rich plasma; rotator cuff tears; shoulder