title: [An autopsy of G-CSF-producing anaplastic carcinoma of the pancreas with impaired accumulation on FDG-PET after S-1 chemotherapy].
abstract: This paper presents a woman in her 70's with G-CSF producing anaplastic carcinoma of the pancreas(Stage IVb)who underwent chemotherapy by S-1 alone. On FDG-PET after the first course, accumulation of FDG was impaired remarkably. After the second course, the patient died of carcinomatous pleuritis and peritonitis on the 88th day after initiation of treatment. G-CSF producing anaplastic carcinoma of the pancreas is extremely rare and there are no reports with regard to response evaluation by FDG-PET. Thus, this case has significant clinical value.
authors.affiliation: Dept. of Internal Medicine, Toyota Kosei Hospital, Japan.
authors.forename: Shohei
authors.initials: S
authors.lastname: Ikeda
authors.forename: Kenji
authors.initials: K
authors.lastname: Okubo
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Shibahara
authors.forename: Michihiko
authors.initials: M
authors.lastname: Narita
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Morita
authors.forename: Atsufumi
authors.initials: A
authors.lastname: Takeuchi
authors.forename: Hironobu
authors.initials: H
authors.lastname: Kanazawa
authors.forename: Takanori
authors.initials: T
authors.lastname: Ito
authors.forename: Daisaku
authors.initials: D
authors.lastname: Nishimura
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Katada
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001344:Autopsy; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000378:metabolism; D004338:Drug Combinations; D017809:Fatal Outcome; D005260:Female; D019788:Fluorodeoxyglucose F18; D016179:Granulocyte Colony-Stimulating Factor / Q000096:biosynthesis; D006801:Humans; D010094:Oxonic Acid / Q000627:therapeutic use*; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000378:metabolism; D010998:Pleurisy / Q000209:etiology; D049268:Positron-Emission Tomography; D005641:Tegafur / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; D019788:Fluorodeoxyglucose F18; D016179:Granulocyte Colony-Stimulating Factor; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid