title: Circadian variation of fatigue in both patients with paralytic poliomyelitis and post-polio syndrome.
abstract: OBJECTIVE
  It was to evaluate the degree of fatigue in patients with paralytic poliomyelitis (PP) and with post-polio syndrome (PPS), and correlate it with parameters of sleep and the circadian cycle.
  
  
  METHODS
  Thirty patients, 17 female (56.7%), participated in the study: they answered the Revised Piper Fatigue Scale and performed a nocturnal polysomnographic study. Eleven had PP (mean age±standard deviation of 47.9±6.4 years), and 19 had PPS (mean age±standard deviation of 46.4±5.6 years).
  
  
  RESULTS
  Our study showed that fatigue was worse in the afternoon in the PP Group and had a progressive increase throughout the day in the PPS Group. We also observed compromised quality of sleep in both groups, but no statically significant difference was found in the sleep parameters measured by polysomnography.
  
  
  CONCLUSIONS
  Fatigue has a well-defined circadian variation, especially in PPS Group. Poor sleep quality is associated with fatigue and, therefore, sleep disturbances should be evaluated and treated in this group of PPS.
authors.affiliation: Departamento de Neurologia, Universidade Federal de São Paulo/Escola Paulista de Medicina (UNIFESP/EPM), São Paulo SP, Brazil. celianafigueiredo@hotmail.com
authors.forename: Celiana Figueiredo
authors.initials: CF
authors.lastname: Viana
authors.forename: Márcia
authors.initials: M
authors.lastname: Pradella-Hallinan
authors.forename: Abrahão Augusto Juviniano
authors.initials: AA
authors.lastname: Quadros
authors.forename: Luis Fabiano
authors.initials: LF
authors.lastname: Marin
authors.forename: Acary Souza Bulle
authors.initials: AS
authors.lastname: Oliveira
mesh_terms: D000328:Adult; D002940:Circadian Rhythm / Q000502:physiology*; D005221:Fatigue / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011051:Poliomyelitis / Q000503:physiopathology*; D017286:Polysomnography; D016262:Postpoliomyelitis Syndrome / Q000503:physiopathology; D012016:Reference Values; D012890:Sleep / Q000502:physiology; D011795:Surveys and Questionnaires; D013997:Time Factors