title: Hrp mutant bacteria as biocontrol agents: toward a sustainable approach in the fight against plant pathogenic bacteria.
abstract: Sustainable agriculture necessitates development of environmentally safe methods to protect plants against pathogens. Among these methods, application of biocontrol agents has been efficiently used to minimize disease development. Here we review current understanding of mechanisms involved in biocontrol of the main Gram-phytopathogenic bacteria-induced diseases by plant inoculation with strains mutated in hrp (hypersensitive response and pathogenicity) genes. These mutants are able to penetrate plant tissues and to stimulate basal resistance of plants. Novel protection mechanisms involving the phytohormone abscisic acid appear to play key roles in the biocontrol of wilt disease induced by Ralstonia solanacearum in Arabidopsis thaliana. Fully understanding these mechanisms and extending the studies to other pathosystems are still required to evaluate their importance in disease protection.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Hanemian
authors.forename: Binbin
authors.initials: B
authors.lastname: Zhou
authors.forename: Laurent
authors.initials: L
authors.lastname: Deslandes
authors.forename: Yves
authors.initials: Y
authors.lastname: Marco
authors.forename: Dominique
authors.initials: D
authors.lastname: Trémousaygue
mesh_terms: D000040:Abscisic Acid / Q000378:metabolism; D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism / Q000382:microbiology; D010935:Plant Diseases / Q000276:immunology / Q000382:microbiology; D010944:Plants / Q000235:genetics / Q000378:metabolism* / Q000382:microbiology*; D043368:Ralstonia solanacearum / Q000472:pathogenicity*
chemical_list: D000040:Abscisic Acid