title: Performance of acceleromyography with a short and light TOF-tube compared with mechanomyography: a clinical comparison.
abstract: BACKGROUND
  Disturbances in the thumb's movement interfere with the functioning of acceleromyography in many clinical settings. The short and light (SL) train-of-four (TOF)-Tube is a new version of a rigid tubular device that was designed to protect the thumb from external disturbances during surgery, even when the hand is not accessible by the anaesthesiologist.
  
  
  OBJECTIVE
  To compare the precision and performance of acceleromyography performed with the aid of the SL TOF-Tube (AMGTT) with standard isometric mechanomyography (MMG).
  
  
  METHODS
  Simultaneous arm-to-arm comparison of both methods in the same anaesthetised patient.
  
  
  METHODS
  A monocentric study, performed from September 2007 to June 2008.
  
  
  METHODS
  Nineteen ASA I to II patients scheduled to undergo lower limb orthopaedic surgery under general anaesthesia.
  
  
  METHODS
  Neuromuscular transmission monitoring during baseline, onset and spontaneous recovery of rocuronium-induced neuromuscular block.
  
  
  METHODS
  Initial baseline and repeatability coefficients were assessed during 10 consecutive measurements of the first twitch height (T1) and TOF T4/T1 ratio and compared using a z test. The spontaneous recoveries of defined blockade levels (onset, T1 25% of initial calibration and TOF ratio 0.9) were compared in terms of duration and intensity. Agreement between both techniques was assessed by the Bland-Altman method.
  
  
  RESULTS
  The mean ± SD control TOF ratios were 98 ± 1% (MMG) and 103 ± 2% (AMGTT). The repeatability coefficients were higher (P < 0.001) and the onset was longer (mean 0.44 min) (P < 0.001) when they were measured by AMGTT. The recoveries of T1 25% and TOF ratio 0.9 were not significantly different between the two methods, and the limits of agreement were in the usual range of contralateral comparisons (-19 and +24% for TOF ratio 0.9).
  
  
  CONCLUSIONS
  Compared with mechanomyography, acceleromyography performed with the aid of an SL TOF-Tube offered acceptable precision and equivalent performance during neuromuscular block recovery.
authors.affiliation: From the Department of Anaesthesiology, University of Louvain, CHU UCL Mont-Godinne-Dinant, Yvoir (PED, JM, MG, CD), MDB Engineering, Spin-off University of Brussels ULB, Brussels (MDB), Scientific Support Unit, University of Louvain, CHU UCL Mont-Godinne-Dinant, Yvoir, Belgium (JJ), and Department of Anaesthesiology, University Hospital, Geneva, Switzerland (AH).
authors.forename: Philippe E
authors.initials: PE
authors.lastname: Dubois
authors.forename: Maxime
authors.initials: M
authors.lastname: De Bel
authors.forename: Jacques
authors.initials: J
authors.lastname: Jamart
authors.forename: John
authors.initials: J
authors.lastname: Mitchell
authors.forename: Maximilien
authors.initials: M
authors.lastname: Gourdin
authors.forename: Christophe
authors.initials: C
authors.lastname: Dransart
authors.forename: Alain
authors.initials: A
authors.lastname: d'Hollander
mesh_terms: D061725:Accelerometry / Q000295:instrumentation* / Q000379:methods*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000732:Androstanols; D000768:Anesthesia, General; D002138:Calibration; D005260:Female; D006801:Humans; D007537:Isometric Contraction / Q000502:physiology; D035002:Lower Extremity / Q000601:surgery; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000295:instrumentation* / Q000379:methods*; D009119:Muscle Contraction / Q000187:drug effects; D009213:Myography / Q000295:instrumentation* / Q000379:methods*; D019148:Neuromuscular Blockade; D003473:Neuromuscular Nondepolarizing Agents; D019637:Orthopedic Procedures; D015203:Reproducibility of Results; D000077123:Rocuronium; D055815:Young Adult
chemical_list: D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D000077123:Rocuronium