title: Assessment of resistance to anoikis in ovarian cancer.
abstract: Anoikis, a form of programmed cell death that occurs due to cell detachment from the extracellular matrix, is a critical mechanism in preventing ectopic cell growth. Acquisition of resistance to anoikis is a prerequisite for epithelial ovarian cancer cells to survive in ascitic fluids before forming metastatic foci. Here we describe a colorimetric method for monitoring the resistance of anoikis of ovarian cancer cells in vitro.
authors.affiliation: Mayo Clinic College of Medicine, Rochester, MN, USA.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: He
authors.forename: Jeremy
authors.initials: J
authors.lastname: Chien
authors.forename: Viji
authors.initials: V
authors.lastname: Shridhar
mesh_terms: D023102:Anoikis / Q000235:genetics*; D017209:Apoptosis / Q000235:genetics; D001202:Ascitic Fluid / Q000473:pathology; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D003124:Colorimetry / Q000379:methods*; D005109:Extracellular Matrix / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis / Q000473:pathology; D010051:Ovarian Neoplasms / Q000235:genetics / Q000473:pathology*