title: Three new compounds from the cultures of basidiomycete Boreostereum vibrans.
abstract: Three new compounds, vibranether (1), myrrhlalkyldiol (2), vibralactone H (3), together with three known compounds, 2-methyl-6-p-tolylheptane-2,3-diol (4), 2-hydroxy-2-methyl-6-p-tolylheptan-3-one (5), and vibralactone (6), were isolated from the cultures of the basidiomycete Boreostereum vibrans. Their structures were determined on the basis of spectroscopic evidences (1D and 2D NMR, HRMS, UV, and IR data), chemical methods, and the literature data. The new compounds displayed no significant cytotoxicities against five human cancer cell lines (IC50>40 μM).
authors.affiliation: a College of Chemistry and Chemical Engineering, Hunan University , Changsha , 410082 , China.
authors.forename: Gang-Qiang
authors.initials: GQ
authors.lastname: Wang
authors.forename: Kun
authors.initials: K
authors.lastname: Wei
authors.forename: Zheng-Hui
authors.initials: ZH
authors.lastname: Li
authors.forename: Tao
authors.initials: T
authors.lastname: Feng
authors.forename: Jian-Hai
authors.initials: JH
authors.lastname: Ding
authors.forename: Qiu-An
authors.initials: QA
authors.lastname: Wang
authors.forename: Ji-Kai
authors.initials: JK
authors.lastname: Liu
mesh_terms: D001487:Basidiomycota / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D007783:Lactones; C522315:vibralactone