title: Deep endometriosis and bladder and detrusor functions in women without urinary symptoms: a pilot study through an unexplored world.
abstract: OBJECTIVE
  To evaluate the impact of deep endometriosis (DE) on bladder function, focusing on detrusor pattern, in patients without preoperative urinary symptoms.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  Academic research center.
  
  
  METHODS
  A total of 25 asymptomatic patients: 12 patients with DE (group 1) and 13 patients with ovarian endometriosis (group 2, control group).
  
  
  METHODS
  Preoperative urodynamic evaluation.
  
  
  METHODS
  The impact of DE on urodynamic parameters.
  
  
  RESULTS
  For the first time, a urodynamic diagnosis of detrusor overactivity was correlated with the presence of deep infiltrating endometriosis (group 1, 91.7% [11/12] vs. group 2, 7.7% [1/13]). All involuntary detrusor contractions were detected only during the filling phase. All cystometry parameters were found to be altered in group 1 and statistically different between the two groups. No pressure/flow study parameter significantly differed between the two groups, besides maximal detrusor pressure (46 cmH2O [33-79] vs. 29 cmH2O [15-40]), which was significantly higher in group 1. Therefore, all detrusor-related parameters are statistically different between the two groups. Postvoid residual does not reach a statistically significant difference.
  
  
  CONCLUSIONS
  DE could significantly impair detrusor functions. A preoperative urodynamic evaluation allows the attainment of important functional information, even in asymptomatic patients.
authors.affiliation: Department of Obstetrics and Gynecology, University of Insubria, Varese, Italy. Electronic address: mauserati@hotmail.com.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Serati
authors.forename: Elena
authors.initials: E
authors.lastname: Cattoni
authors.forename: Andrea
authors.initials: A
authors.lastname: Braga
authors.forename: Stefano
authors.initials: S
authors.lastname: Uccella
authors.forename: Antonella
authors.initials: A
authors.lastname: Cromi
authors.forename: Fabio
authors.initials: F
authors.lastname: Ghezzi
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004715:Endometriosis / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D010049:Ovarian Diseases / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D010865:Pilot Projects; D011237:Predictive Value of Tests; D011300:Preoperative Care; D011312:Pressure; D011446:Prospective Studies; D012187:Retroperitoneal Space; D012307:Risk Factors; D001743:Urinary Bladder / Q000503:physiopathology*; D053201:Urinary Bladder, Overactive / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D014563:Urodynamics; D055815:Young Adult
keywords: Deep endometriosis; bladder function; detrusor overactivity; urodynamics