title: Concentrated arabinoxylan but not concentrated β-glucan in wheat bread has similar effects on postprandial insulin as whole-grain rye in porto-arterial catheterized pigs.
abstract: The acute glycemic effects of concentrated dietary fibers (DF) versus whole-grain rye were studied in porto-arterial catheterized pigs. Two white wheat breads with wheat arabinoxylan (AX) or oat β-glucan (BG), two rye breads with intact rye kernels (RK) or milled rye (GR), and a low DF white wheat bread were fed to six pigs in a randomized crossover design. Blood profiles were collected for 4 h after feeding. Glucose absorption was reduced in pigs fed the AX bread at 60 min postprandial (3.1 mmol/min for AX compared to 9.4 mmol/min for WF, P = 0.02) and insulin secretion was lowered at 30 min postprandial for AX and GR (74.4 and 129 pmol/min for AX and GR, respectively, compared to 738 pmol/min for WF, P < 0.04). In conclusion, the GR and AX breads were most effective in improving insulin economy, suggesting that arabinoxylan from wheat and rye induces similar outcomes in the metabolic response.
authors.affiliation: Department of Animal Science, Aarhus University , Blichers Allé 20, DK-8830 Tjele, Denmark.
authors.forename: Kirstine L
authors.initials: KL
authors.lastname: Christensen
authors.forename: Mette S
authors.initials: MS
authors.lastname: Hedemann
authors.forename: Helle N
authors.initials: HN
authors.lastname: Lærke
authors.forename: Henry
authors.initials: H
authors.lastname: Jørgensen
authors.forename: Shivaprakash J
authors.initials: SJ
authors.lastname: Mutt
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Herzig
authors.forename: Knud E
authors.initials: KE
authors.lastname: Bach Knudsen
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D001939:Bread / Q000032:analysis*; D004043:Dietary Fiber / Q000378:metabolism*; D005260:Female; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D023421:Models, Animal; D019518:Postprandial Period; D011897:Random Allocation; D012434:Secale / Q000737:chemistry / Q000378:metabolism*; D013552:Swine; D014908:Triticum / Q000737:chemistry / Q000378:metabolism*; D014990:Xylans / Q000378:metabolism*; D047071:beta-Glucans / Q000378:metabolism*
chemical_list: D001786:Blood Glucose; D004043:Dietary Fiber; D007328:Insulin; D014990:Xylans; D047071:beta-Glucans; C085118:arabinoxylan