title: Surface acoustic wave microfluidics.
abstract: The recent introduction of surface acoustic wave (SAW) technology onto lab-on-a-chip platforms has opened a new frontier in microfluidics. The advantages provided by such SAW microfluidics are numerous: simple fabrication, high biocompatibility, fast fluid actuation, versatility, compact and inexpensive devices and accessories, contact-free particle manipulation, and compatibility with other microfluidic components. We believe that these advantages enable SAW microfluidics to play a significant role in a variety of applications in biology, chemistry, engineering and medicine. In this review article, we discuss the theory underpinning SAWs and their interactions with particles and the contacting fluids in which they are suspended. We then review the SAW-enabled microfluidic devices demonstrated to date, starting with devices that accomplish fluid mixing and transport through the use of travelling SAW; we follow that by reviewing the more recent innovations achieved with standing SAW that enable such actions as particle/cell focusing, sorting and patterning. Finally, we look forward and appraise where the discipline of SAW microfluidics could go next.
authors.affiliation: Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
authors.forename: Xiaoyun
authors.initials: X
authors.lastname: Ding
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.forename: Sz-Chin Steven
authors.initials: SC
authors.lastname: Lin
authors.forename: Zackary S
authors.initials: ZS
authors.lastname: Stratton
authors.forename: Nitesh
authors.initials: N
authors.lastname: Nama
authors.forename: Feng
authors.initials: F
authors.lastname: Guo
authors.forename: Daniel
authors.initials: D
authors.lastname: Slotcavage
authors.forename: Xiaole
authors.initials: X
authors.lastname: Mao
authors.forename: Jinjie
authors.initials: J
authors.lastname: Shi
authors.forename: Francesco
authors.initials: F
authors.lastname: Costanzo
authors.forename: Tony Jun
authors.initials: TJ
authors.lastname: Huang
mesh_terms: D002469:Cell Separation / Q000295:instrumentation; D006801:Humans; D050866:Liquid Crystals / Q000737:chemistry; D044085:Microfluidics / Q000295:instrumentation*; D008962:Models, Theoretical; D037742:Nanotubes, Carbon / Q000737:chemistry; D013016:Sound
chemical_list: D037742:Nanotubes, Carbon
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