title: Topical timolol 0.5% gel-forming solution for small deep facial infantile hemangiomas.
abstract: We report three cases of successful treatment of proliferating deep infantile hemangiomas with topical timolol 0.5% gel-forming solution (GFS) used two to three times daily. We recommend considering timolol as an initial option for small, deep facial hemangiomas that are not causing functional compromise or complications but may have an unsatisfactory cosmetic appearance. In our experience, albeit limited, this is a safe alternative to watchful waiting.
authors.affiliation: Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Sorrell
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Chamlin
mesh_terms: D000287:Administration, Topical; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D005153:Facial Neoplasms / Q000188:drug therapy*; D005260:Female; D005782:Gels; D006391:Hemangioma / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008297:Male; D012878:Skin Neoplasms / Q000188:drug therapy*; D013999:Timolol / Q000008:administration & dosage*; D016896:Treatment Outcome; D057832:Watchful Waiting
chemical_list: D000319:Adrenergic beta-Antagonists; D005782:Gels; D013999:Timolol