title: Cerium ammonium nitrate (CAN)-catalyzed four-component one-pot synthesis of multi-substituted pyrano[2,3-c] pyrazoles under ultrasound irradiation.
abstract: A convenient and efficient synthesis of multi-substituted dihydropyrano[2,3-c]pyrazole derivatives is reported. The four-component reaction of 4-hydrazinobenzoic acid, β-keto esters, aromatic aldehydes, and malononitrile using 10 mol% CAN catalyst in water under ultrasound irradiation produced the target compounds in good-to-excellent yields. This method has advantages over conventional methods in being economic, non-toxic, and environmentally compatible due to its use of efficient and eco-friendly CAN catalyst and water solvent.
authors.affiliation: Key Laboratory of Oil & Gas Fine Chemicals, Ministry of Education & Xinjiang Uyghur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Ürümqi, 830046, People's Republic of China, ablajan209@hotmail.com.
authors.forename: Keyume
authors.initials: K
authors.lastname: Ablajan
authors.forename: Wang
authors.initials: W
authors.lastname: Liju
authors.forename: Yakefujiang
authors.initials: Y
authors.lastname: Kelimu
authors.forename: Feng
authors.initials: F
authors.lastname: Jun
mesh_terms: D002384:Catalysis; D002563:Cerium / Q000737:chemistry*; D015394:Molecular Structure; D009566:Nitrates / Q000737:chemistry*; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D013010:Sonication
chemical_list: D009566:Nitrates; D011720:Pyrazoles; D012997:Solvents; C032786:cerium nitrate; D002563:Cerium; C031280:pyrazole; C006568:ammonium nitrate
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