title: Vitamin E and its clinical challenges in cosmetic and reconstructive medicine with focus on scars; a review.
abstract: Hypertrophic scars are abnormal scars that develop after wound-healing, especially in some ethnic backgrounds. The after-effects of these scars result in depression, posttraumatic stress syndrome, anxiety, impaired self-esteem and quality of life. Treatment of these scars still is a subject of different studies and is a challenging issue in reconstructive medicine. We reviewed the current published articles about the effects of vitamin E on scar formation and its clinical effectiveness. The application of vitamin E is popular interest, but it still needs more clinical studies to establish its perceived outcomes.
authors.affiliation: Department of General Surgery, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Nasrin
authors.initials: N
authors.lastname: Rahmani
authors.forename: Seyyed Abbas
authors.initials: SA
authors.lastname: Hashemi
authors.forename: Sara
authors.initials: S
authors.lastname: Ehteshami
mesh_terms: D017439:Cicatrix, Hypertrophic / Q000188:drug therapy*; D003357:Cosmetic Techniques; D006801:Humans; D019651:Plastic Surgery Procedures; D014810:Vitamin E / Q000494:pharmacology*
chemical_list: D014810:Vitamin E