title: [Targeted nanomedicine in diagnostics and therapy of neurological diseases].
abstract: The incidence of neurological diseases increases. The up to date diagnostics and therapeutics approaches require the cost-effective and personalized solutions. The nanomedicine now, --and likely more in the future--opens a new horizon in the treatment of neurological diseases. The nano-size materials have several advantages that make it their use as drug delivery systems, and imaging agent. Very important aspect is that these materials can transfer across the blood-brain barrier. The functionalization and surface modification of nanomaterials enhances this effect. The authors summarize of neurological application of nanoparticles according to the current data. They provide an overview about the most common used nanomedical materials, targeted drug delivery mechanisms and nano-imaging opportunities.
authors.affiliation: Miskolci Egyetem, Egészségügyi Kar, Nanobiotechnológiai és Regenerativ Medicina Tanszék, Miskolc. fodor@uni-miskolc.hu
authors.forename: Fodor
authors.initials: F
authors.lastname: Bertalan
authors.forename: Barkai
authors.initials: B
authors.lastname: László
authors.forename: Valikovics
authors.initials: V
authors.lastname: Attila
mesh_terms: D001812:Blood-Brain Barrier / Q000187:drug effects; D050091:Dendrimers / Q000737:chemistry / Q000627:therapeutic use; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D008081:Liposomes / Q000737:chemistry / Q000627:therapeutic use; D050997:Nanomedicine / Q000379:methods* / Q000639:trends; D053758:Nanoparticles / Q000737:chemistry / Q000627:therapeutic use; D049329:Nanostructures / Q000737:chemistry* / Q000627:therapeutic use*; D009422:Nervous System Diseases / Q000175:diagnosis* / Q000188:drug therapy*; D059906:Neuroimaging / Q000379:methods*; D011108:Polymers / Q000737:chemistry / Q000627:therapeutic use
chemical_list: D050091:Dendrimers; D008081:Liposomes; D011108:Polymers