title: Transplantable liver organoids made from only three ingredients.
abstract: Liver cell therapies using induced pluripotent stem cells (iPSCs) are in development. A recent paper in Nature by Takebe et al. expands the range of liver diseases that could be treated with iPSC-derived hepatocytes by combining them with endothelial and stromal cells to generate organoids that survive and function extrahepatically.
authors.affiliation: Department of Surgery, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, and Liver Center, University of California, San Francisco, San Francisco, CA 94143, USA. willenbringh@stemcell.ucsf.edu
authors.forename: Holger
authors.initials: H
authors.lastname: Willenbring
authors.forename: Alejandro
authors.initials: A
authors.lastname: Soto-Gutierrez
mesh_terms: D000818:Animals; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology*; D008099:Liver / Q000098:blood supply* / Q000502:physiology*; D044968:Regenerative Medicine / Q000379:methods*
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