title: Risk factors for severe diverticulitis in computed tomography-confirmed acute diverticulitis in Korea.
abstract: OBJECTIVE
  Acute complicated diverticulitis can be subdivided into moderate diverticulitis and severe diverticulitis. Although there have been numerous studies on the risk factors for complicated diverticulitis, little research has focused on severe diverticulitis. This study was designed to identify the risk factors for severe diverticulitis in an acute diverticulitis attack using the modified Hinchey classification.
  
  
  METHODS
  Patients were included if they had any evidence of acute diverticulitis detected by computed tomography. The patients were subdivided into severe diverticulitis (Hinchey class ≥Ib; abscesses or peritonitis) and moderate diverticulitis (Hinchey class Ia; pericolic inflammation) groups.
  
  
  RESULTS
  Of the 128 patients, 25 exhibited severe diverticulitis, and 103 exhibited moderate diverticulitis. In a multivariate analysis, age >50 years (odds ratio [OR], 5.27; p=0.017), smoking (OR, 3.61; p=0.044), comorbidity (OR, 4.98; p=0.045), leukocytosis (OR, 7.70; p=0.003), recurrence (OR, 4.95; p=0.032), and left-sided diverticulitis (OR, 6.92; p=0.006) were significantly associated with severe diverticulitis.
  
  
  CONCLUSIONS
  This study suggests that the risk factors for severe diverticulitis are age >50 years, smoking, comorbidity, leukocytosis, recurrent episodes, and left-sided diverticulitis.
authors.affiliation: Division of Gastroenterology and Hepatology, Department of Internal Medicine, Institute of Digestive Disease and Nutrition, Korea University College of Medicine, Seoul, Korea.
authors.forename: Nark-Soon
authors.initials: NS
authors.lastname: Park
authors.forename: Yoon Tae
authors.initials: YT
authors.lastname: Jeen
authors.forename: Hyuk Soon
authors.initials: HS
authors.lastname: Choi
authors.forename: Eun Sun
authors.initials: ES
authors.lastname: Kim
authors.forename: Young Jin
authors.initials: YJ
authors.lastname: Kim
authors.forename: Bora
authors.initials: B
authors.lastname: Keum
authors.forename: Yeon Seok
authors.initials: YS
authors.lastname: Seo
authors.forename: Hoon Jai
authors.initials: HJ
authors.lastname: Chun
authors.forename: Hong Sik
authors.initials: HS
authors.lastname: Lee
authors.forename: Soon Ho
authors.initials: SH
authors.lastname: Um
authors.forename: Chang Duck
authors.initials: CD
authors.lastname: Kim
authors.forename: Ho Sang
authors.initials: HS
authors.lastname: Ryu
keywords: Computed tomography; Diverticulitis; Hinchey classification; Severity
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