title: Interferons in hematopoiesis and leukemia.
abstract: Interferons not only exert a fundamental role during inflammation and immune responses but also modulate the activity of hematopoietic stem cells during homeostatic and demand-adapted hematopoiesis. Identical mechanisms regulate the homeostasis and proliferation of leukemic stem cells (LSCs). Understanding these mechanisms may lead to novel therapeutic approaches against leukemia.
authors.affiliation: Tumor Immunology; Department of Clinical Research; University of Bern; Bern, Switzerland ; Institute of Pathology; University of Bern; Bern, Switzerland.
authors.forename: Christian M
authors.initials: CM
authors.lastname: Schürch
authors.forename: Carsten
authors.initials: C
authors.lastname: Riether
authors.forename: Adrian F
authors.initials: AF
authors.lastname: Ochsenbein
keywords: hematopoiesis; hematopoietic stem cells; interferon; leukemia; leukemia stem cells
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