title: Functionalization protocols of silicon micro/nano-mechanical biosensors.
abstract: Functionalization is a key element in biodetection technologies such as micro/nano-mechanical sensors. Since assay sensitivity and stability drastically depends on a proper bioreceptor immobilization, the sensing surface must be first chemically modified with uniform, well-packed, and robust layers. Here, we describe three functionalization protocols that we developed for the surface modification with amino, aldehyde, and carboxyl groups of micro/nano-mechanical biosensors.
authors.affiliation: Politecnico di Torino, Torino, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Frascella
authors.forename: Carlo
authors.initials: C
authors.lastname: Ricciardi
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D055616:Microtechnology / Q000295:instrumentation / Q000379:methods*; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods*; D012825:Silicon / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D012825:Silicon