title: Breast MRI at 7 Tesla with a bilateral coil and T1-weighted acquisition with robust fat suppression: image evaluation and comparison with 3 Tesla.
abstract: OBJECTIVE
  To evaluate the image quality of T1-weighted fat-suppressed breast MRI at 7 T and to compare 7-T and 3-T images.
  
  
  METHODS
  Seventeen subjects were imaged using a 7-T bilateral transmit-receive coil and 3D gradient echo sequence with adiabatic inversion-based fat suppression (FS). Images were graded on a five-point scale and quantitatively assessed through signal-to-noise ratio (SNR), fibroglandular/fat contrast and signal uniformity measurements.
  
  
  RESULTS
  Image scores at 7 and 3 T were similar on standard-resolution images (1.1 × 1.1 × 1.1-1.6 mm(3)), indicating that high-quality breast imaging with clinical parameters can be performed at 7 T. The 7-T SNR advantage was underscored on 0.6-mm isotropic images, where image quality was significantly greater than at 3 T (4.2 versus 3.1, P ≤ 0.0001). Fibroglandular/fat contrast was more than two times higher at 7 T than at 3 T, owing to effective adiabatic inversion-based FS and the inherent 7-T signal advantage. Signal uniformity was comparable at 7 and 3 T (P < 0.05). Similar 7-T image quality was observed in all subjects, indicating robustness against anatomical variation.
  
  
  CONCLUSIONS
  The 7-T bilateral transmit-receive coil and adiabatic inversion-based FS technique produce image quality that is as good as or better than at 3 T.
  
  
  CONCLUSIONS
  • High image quality bilateral breast MRI is achievable with clinical parameters at 7 T. • 7-T high-resolution imaging improves delineation of subtle soft tissue structures. • Adiabatic-based fat suppression provides excellent fibroglandular/fat contrast at 7 T. • 7- and 3-T 3D T1-weighted gradient-echo images have similar signal uniformity. • The 7-T dual solenoid coil enables bilateral imaging without compromising uniformity.
authors.affiliation: Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Langone Medical Center, 660 First Avenue, Room 401, New York, NY, USA, ryan.brown@nyumc.org.
authors.forename: Ryan
authors.initials: R
authors.lastname: Brown
authors.forename: Pippa
authors.initials: P
authors.lastname: Storey
authors.forename: Christian
authors.initials: C
authors.lastname: Geppert
authors.forename: KellyAnne
authors.initials: K
authors.lastname: McGorty
authors.forename: Ana Paula Klautau
authors.initials: AP
authors.lastname: Leite
authors.forename: James
authors.initials: J
authors.lastname: Babb
authors.forename: Daniel K
authors.initials: DK
authors.lastname: Sodickson
authors.forename: Graham C
authors.initials: GC
authors.lastname: Wiggins
authors.forename: Linda
authors.initials: L
authors.lastname: Moy
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D000328:Adult; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004867:Equipment Design; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008875:Middle Aged; D015203:Reproducibility of Results; D059629:Signal-To-Noise Ratio; D055815:Young Adult
references.citation: AJR Am J Roentgenol. 2009 Sep;193(3):840-9
references.pmid: 19696300
references.citation: Magn Reson Med. 2004 Jan;51(1):35-45
references.pmid: 14705043
references.citation: Eur Radiol. 1997;7 Suppl 5:276-80
references.pmid: 9370559
references.citation: Acad Radiol. 2010 Aug;17(8):1050-6
references.pmid: 20599158
references.citation: Magn Reson Med. 1991 Apr;18(2):371-83
references.pmid: 2046518
references.citation: J Magn Reson Imaging. 2010 Jan;31(1):234-9
references.pmid: 20027594
references.citation: NMR Biomed. 2013 Apr;26(4):367-75
references.pmid: 23076877
references.citation: J Magn Reson Imaging. 2012 Oct;36(4):865-72
references.pmid: 22730242
references.citation: Invest Radiol. 2011 Jun;46(6):370-6
references.pmid: 21317792
references.citation: Magn Reson Imaging. 2013 May;31(4):613-7
references.pmid: 23116848
references.citation: Magn Reson Med. 1997 Nov;38(5):852-7
references.pmid: 9358462
references.citation: Magn Reson Imaging Clin N Am. 2007 Aug;15(3):315-20, vi
references.pmid: 17893052
references.citation: Magn Reson Med. 2011 Jul;66(1):281-9
references.pmid: 21287593
references.citation: J Magn Reson Imaging. 2013 Aug;38(2):454-9
references.pmid: 23292822
references.citation: Radiology. 2007 Sep;244(3):929-30
references.pmid: 17709843
references.citation: Phys Med Biol. 2007 Oct 21;52(20):6093-115
references.pmid: 17921574
references.citation: AJR Am J Roentgenol. 2011 May;196(5):W641-7
references.pmid: 21512057
references.citation: Radiology. 2005 Dec;237(3):1014-9
references.pmid: 16237142
references.citation: Radiology. 2012 Jul;264(1):51-8
references.pmid: 22589320