title: Improved weight gain in very-low-birth-weight infants after the introduction of a self-created computer calculation program for individualized parenteral nutrition.
abstract: BACKGROUND
  Although 90% of babies <1500 g (very-low-birth-weight or VLBW) are appropriate for gestational age (AGA) at birth, almost all are small for gestational age at 36 weeks of gestation, mainly due to nutritional deficiency in the first weeks of life. A computer calculation program (CCP) to calculate parenteral nutrition (PN) was introduced to improve nutritional intake in preterm infants.
  
  
  METHODS
  Somatometric data and composition of PN of VLBW infants were compared with two points of time measured over a period of 4 years.
  
  
  RESULTS
  Data from 56 patients born before the introduction of the CCP (2001-2002) and 59 patients born after the introduction of the CCP (2004-2005) were obtained. Although the number of AGA infants at birth did not differ, the computer-calculated group had significantly more AGA infants at the time of discharge from hospital (44% vs. 14%, p < 0.05). In this group, more protein and fat were administered in the first 5 days of life (7.3 g/kg vs. 4.5 g/kg, p < 0.05 and 5 g/kg vs. 0.5 g/kg, p < 0.05) and the duration of total PN was shorter (16 days vs. 24 days, p < 0.05).
  
  
  CONCLUSIONS
  Because the CCP contributes to a better weight gain in VLBW infants due to simplification of PN calculation, we suggest its use in the calculation of PN in VLBW infants.
authors.affiliation: Department of Pediatrics II (Neonatology), Innsbruck Medical University, Innsbruck, Austria.
authors.forename: Maria
authors.initials: M
authors.lastname: Gnigler
authors.affiliation: Department of Pediatrics II (Neonatology), Innsbruck Medical University, Innsbruck, Austria.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Schlenz
authors.affiliation: Department of Pediatrics II (Neonatology), Innsbruck Medical University, Innsbruck, Austria.
authors.forename: Ursula
authors.initials: U
authors.lastname: Kiechl-Kohlendorfer
authors.affiliation: Department of Neonatology and Pediatric Intensive Care, University Hospital Carl Gustav Carus, Dresden, Germany.
authors.forename: Mario
authors.initials: M
authors.lastname: Rüdiger
authors.affiliation: Department of Pediatrics II (Neonatology), Innsbruck Medical University, Innsbruck, Austria. Electronic address: Salvador.navarro-Psihas@uki.at.
authors.forename: Salvador
authors.initials: S
authors.lastname: Navarro-Psihas
mesh_terms: D005260:Female; D006801:Humans; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight / Q000254:growth & development*; D008297:Male; D009017:Morbidity; D010288:Parenteral Nutrition; D012984:Software; D015430:Weight Gain
keywords: growth retardation; parenteral nutrition; small for gestational age; very-low-birth-weight infant; weight gain