title: Renal replacement therapy after cardiac surgery; renal function recovers.
abstract: OBJECTIVE
  To assess renal outcome in patients discharged from hospital following cardiac surgery-associated acute kidney injury (CSA-AKI) with need for renal replacement therapy.
  
  
  METHODS
  In April 2012 we conducted a cross-sectional study of patients treated with renal replacement therapy following cardiac surgery during 2008-2010. We included all adult patients with a pre-operative serum creatinine (sCr) < 200 μM, surviving to discharge. Primary endpoint was use of renal replacement therapy after hospital discharge; secondary endpoint was a sCr > 200 μM at the time of follow-up.
  
  
  RESULTS
  We reviewed the records of 3828 patients receiving cardiac surgery in the defined period. A total of 107 adult patients with sCr concentrations < 200 μM were treated with post-operative renal replacement therapy of whom 70 survived to discharge. Fifty-six patients were alive at follow-up and none had required renal replacement therapy after initial discharge. Median sCr concentration at follow-up was 111 [56-257] μM and two patients had sCr above 200 μM.
  
  
  CONCLUSIONS
  In this study, renal function recovered in patients discharged from hospital following renal replacement therapy after CSA-AKI. No patients needed further renal replacement therapy and only two (4%) had a sCr > 200 μM at follow-up.
authors.affiliation: Department of Cardiothoracic Surgery, Rigshospitalet, Copenhagen University Hospital , Copenhagen , Denmark.
authors.forename: Kristin Julia
authors.initials: KJ
authors.lastname: Steinthorsdottir
authors.forename: Kristian
authors.initials: K
authors.lastname: Kandler
authors.forename: Nis
authors.initials: N
authors.lastname: Agerlin Windeløv
authors.forename: Daniel Andreas
authors.initials: DA
authors.lastname: Steinbrüchel
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D003404:Creatinine / Q000097:blood; D003430:Cross-Sectional Studies; D003718:Denmark / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D057234:Preoperative Period; D017582:Renal Replacement Therapy
chemical_list: D003404:Creatinine