title: [Bone mineral density and adequacy of dietary pattern of patients with chronic kidney disease in hemodialysis].
abstract: BACKGROUND
  In chronic kidney disease (CKD) patients, malnutrition is common with loss of muscle mass and decreased bone mineral density (BMD), increasing the risk of morbidity.
  
  
  OBJECTIVE
  To compare body composition, bone mineral density (BMD) and bone mineral content (BMC) between CKD patients and healthy subjects, and relate these parameters with energy, macronutrients and micronutrients intake.
  
  
  METHODS
  Body composition was assessed 30 haemodialysis patients and compared with 28 healthy volunteers with DEXA. In patients, three 24 hours records of dietary intake were filled.
  
  
  RESULTS
  A significantly lower BMD (p < 0.01) and BMC (p < 0.0) were found in CKD patients. There was a trend for patients to have lower fat free mass (FFM) than controls (p = 0.06). In men, differences in BMD and BMC lost significance when adjusting for fat mass FM (%) and FFM (kg). In CKD, 34.5% and 27.6% of patients had an adequate intake of energy and protein, respectively. However, it was observed a deficit of energy and protein intake in 31.0% and 44.8% of patients, respectively. No significant correlation was found in CKD patients between macronutrient and calcium intake and BMD or BMC.
  
  
  CONCLUSIONS
  CKD have lower BMD and BMC than healthy volunteers. These differences lost significance in men, after adjusting for body composition parameters. A poor dietary adequacy was found in most patients with CKD, but no association was observed between these variables and body composition or bone mineral density.
authors.affiliation: Departamento de Nutrición, Facultad de Medicina, Universidad de Chile, Chile.
authors.forename: Fernando
authors.initials: F
authors.lastname: Carrasco
authors.forename: Marcelo
authors.initials: M
authors.lastname: Cano
authors.forename: Jean
authors.initials: J
authors.lastname: Camousseigt
authors.forename: Pamela
authors.initials: P
authors.lastname: Rojas
authors.forename: Jorge
authors.initials: J
authors.lastname: Inostroza
authors.forename: Rubén
authors.initials: R
authors.lastname: Torres
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001823:Body Composition / Q000502:physiology; D015519:Bone Density / Q000502:physiology*; D002908:Chronic Disease; D004032:Diet; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D006435:Renal Dialysis; D051436:Renal Insufficiency, Chronic / Q000473:pathology* / Q000628:therapy*; D055815:Young Adult