title: Control of nanoparticles on branched DNA nanostructures.
abstract: Recently, DNA has been used to guide the self-assembly of functional materials. Based on programmability of DNA, branched DNA nanostructures were created and precisely labeled with quantum dots and gold nanoparticles. The precise molecular recognition of DNA allows the precise design and synthesis of multifunctional hybrid materials by building DNA nanostructures. The first step of obtaining multi-functionality is to precisely label function materials on DNA building block or branched DNA before construction of complicated nanostructures. In this paper, we introduce the two routes to label functional nanoparticle on DNA structure. Quantum dots were successfully conjugated on branched DNA by streptavidin-biotin interaction and gold nanoparticles were attached on the DNA nanostructure by hybridization.
authors.affiliation: Department of Chemical Engineering, University of Seoul, Seoulsiripdaero 163, Dongdaemun-gu, Seoul 130-743, Republic of Korea. JBLEE@uos.ac.kr
authors.forename: Jong Bum
authors.initials: JB
authors.lastname: Lee
authors.forename: Hyuncheol
authors.initials: H
authors.lastname: Kim
mesh_terms: D003460:Crystallization / Q000379:methods*; D004247:DNA / Q000737:chemistry* / Q000648:ultrastructure*; D046911:Macromolecular Substances / Q000737:chemistry; D008422:Materials Testing; D008968:Molecular Conformation; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size; D045663:Quantum Dots; D013194:Staining and Labeling / Q000379:methods; D013499:Surface Properties
chemical_list: D046911:Macromolecular Substances; D004247:DNA