title: ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy.
abstract: Tumor cells succumb to chemotherapy while releasing ATP. We have found that extracellular ATP attracts dendritic cell (DC) precursors into the tumor bed, facilitates their permanence in the proximity of dying cells and promotes their differentiation into mature DCs endowed with the capacity of presenting tumor-associated antigens.
authors.affiliation: INSERM, U848; Villejuif, France ; Institut Gustave Roussy; Villejuif, France ; Université Paris Sud/Paris XI; Le Kremlin Bicêtre; Paris, France.
authors.forename: Yuting
authors.initials: Y
authors.lastname: Ma
authors.forename: Sandy
authors.initials: S
authors.lastname: Adjemian
authors.forename: Heng
authors.initials: H
authors.lastname: Yang
authors.forename: João Paulo Portela
authors.initials: JP
authors.lastname: Catani
authors.forename: Dalil
authors.initials: D
authors.lastname: Hannani
authors.forename: Isabelle
authors.initials: I
authors.lastname: Martins
authors.forename: Mickaël
authors.initials: M
authors.lastname: Michaud
authors.forename: Oliver
authors.initials: O
authors.lastname: Kepp
authors.forename: Abdul Qader
authors.initials: AQ
authors.lastname: Sukkurwala
authors.forename: Erika
authors.initials: E
authors.lastname: Vacchelli
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Galluzzi
authors.forename: Laurence
authors.initials: L
authors.lastname: Zitvogel
authors.forename: Guido
authors.initials: G
authors.lastname: Kroemer
keywords: CD39; apoptosis; autophagy; calreticulin; doxorubicin; immunogenic cell death
references.citation: Science. 2011 Dec 16;334(6062):1573-7
references.pmid: 22174255
references.citation: Annu Rev Immunol. 2013;31:51-72
references.pmid: 23157435
references.citation: Cell Cycle. 2009 Nov 15;8(22):3723-8
references.pmid: 19855167
references.citation: Immunity. 2013 Apr 18;38(4):729-41
references.pmid: 23562161
references.citation: Oncoimmunology. 2012 May 1;1(3):393-395
references.pmid: 22737627
references.citation: Oncoimmunology. 2012 Mar 1;1(2):179-188
references.pmid: 22720239
references.citation: Science. 2012 Sep 28;337(6102):1678-84
references.pmid: 23019653
references.citation: J Exp Med. 2011 Mar 14;208(3):491-503
references.pmid: 21383056
references.citation: Nat Rev Drug Discov. 2012 Feb 03;11(3):215-33
references.pmid: 22301798
references.citation: Oncoimmunology. 2012 Nov 1;1(8):1323-1343
references.pmid: 23243596