title: [Effects of bromocriptine on the treatment of prolactinomas in male patients and its influences on their sexual function].
abstract: OBJECTIVE
  To explore the effect of bromocriptine in the treatment of male patients with prolactinoma and its impacts on their sexual function.
  
  
  METHODS
  The clinical data of 29 male patients with prolactinomas treated with Bromocriptine were analysed, International Index of Erectile Function-5 (IIEF-5) was used to assess the sexual function of married patients before and after the treatment of Bromocriptine.
  
  
  RESULTS
  The main clinical symptoms of male patients with prolactinomas were sexual dysfunction, headache and hypopsia, which were released significantly at 6 months after Bromocriptine therapy, with the decrease of serum prolactin (PRL) level (P < 0.05) and the improvement of basal testosterone (T) level (P < 0.05). The total normalization rate of PRL was 82.8%, and total effective rate of Bromocriptine therapy was 100%. According to the assessment of IIEF-5, all the male patients had their sexual function improved in various degree.
  
  
  CONCLUSIONS
  Bromocriptine can improve the clinical symptoms of male patients with prolactinoma and their sexual function.
authors.affiliation: Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Xin-Cheng
authors.initials: XC
authors.lastname: Xue
authors.forename: Shu
authors.initials: S
authors.lastname: Jiang
authors.forename: Sen-Lin
authors.initials: SL
authors.lastname: Yin
authors.forename: Chuan-Hong
authors.initials: CH
authors.lastname: Zhong
authors.forename: Pei-Zhi
authors.initials: PZ
authors.lastname: Zhou
authors.forename: Shu-Wen
authors.initials: SW
authors.lastname: Cheng
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001971:Bromocriptine / Q000627:therapeutic use*; D007172:Erectile Dysfunction; D006727:Hormone Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000188:drug therapy*; D011388:Prolactin / Q000097:blood; D015175:Prolactinoma / Q000188:drug therapy*; D012735:Sexual Dysfunction, Physiological / Q000188:drug therapy*; D013739:Testosterone / Q000097:blood; D055815:Young Adult
chemical_list: D006727:Hormone Antagonists; D001971:Bromocriptine; D013739:Testosterone; D011388:Prolactin