title: [Effect of electroacupuncture combined epidural anesthesia on plasma concentration of IL-1beta in patients undergoing gynecological surgery].
abstract: OBJECTIVE
  To study the effect of electroacupuncture (EA) combined epidural anesthesia on plasma concentration of IL-1beta in patients undergoing gynecological surgery.
  
  
  METHODS
  Forty patients who were scheduled to receive gynecological operation under epidural anesthesia were randomly assigned to the epidural anesthesia group (Group A, 20 cases) and the epidural combined EA group (Group B, 20 cases). All patients in the two groups received epidural anesthesia. Continuous EA at Zusanli (ST36) and Sanyinjiao (SP6) with the frequency of 30 -100 Hz was applied in those in Group B. The peri-operative hemodynamic changes, visual analog scale (VAS), and the plasma concentration of IL-1 3 were observed.
  
  
  RESULTS
  There was no statistical difference in peri-operative hemodynamic changes between the two groups (P >0.05). Compared with Group A, the VAS was lower in Group B at post-operative 8, 24, and 48 h, respectively (P <0.05), and the plasma concentration of IL-1beta was also lower in Group B at post-operative 4 h, 24 h, and 3 days (P <0. 05).
  
  
  CONCLUSIONS
  Acupuncture could ease postoperative pain and reduce the plasma concentration of IL-1beta.
authors.affiliation: Department of Anesthesiology, Wuhan Hospital of Integrative Medicine, Wuhan 430022, China.
authors.forename: Xin-Min
authors.initials: XM
authors.lastname: Feng
authors.forename: Jin
authors.initials: J
authors.lastname: Li
mesh_terms: D000328:Adult; D000767:Anesthesia, Epidural; D015671:Electroacupuncture; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D053583:Interleukin-1beta / Q000097:blood*; D007432:Intraoperative Period; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy
chemical_list: D053583:Interleukin-1beta