title: Solid organ transplants in HIV-infected patients.
abstract: There is a growing need for kidney and liver transplants in persons living with HIV. Fortunately, with the significant advances in antiretroviral therapy and management of opportunistic infections, HIV infection is no longer an absolute contraindication for solid organ transplantation. Data from several large prospective multi-center cohort studies have shown that solid organ transplantation in carefully selected HIV-infected individuals is safe. However, significant challenges have been identified including prevention of acute rejection, management of drug-drug interactions and treatment of recurrent viral hepatitis. This article reviews the selection criteria, outcomes, and special management considerations for HIV-infected patients undergoing liver or kidney transplantation.
authors.affiliation: Department of Surgery, University of California San Francisco, 513 Parnassus Ave., Room S321, San Francisco, CA 94143, USA. jack.harbell@ucsfmedctr.org
authors.forename: Jack
authors.initials: J
authors.lastname: Harbell
authors.forename: Norah A
authors.initials: NA
authors.lastname: Terrault
authors.forename: Peter
authors.initials: P
authors.lastname: Stock
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000517:prevention & control; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D058625:End Stage Liver Disease / Q000601:surgery*; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation; D016031:Liver Transplantation; D018579:Patient Selection
chemical_list: D044966:Anti-Retroviral Agents
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