title: Evidence on acne therapy.
abstract: Among the current treatments available for acne vulgaris, many widely practiced options lack support from studies at the best level of scientific evidence. The aim of this narrative review was to present the very latest information on topical and systemic treatments for acne vulgaris. Information from systematic reviews and well-designed clinical trials, obtained through a systematic search of the major medical databases, is emphasized. There are important issues regarding the clinical management of acne that still lack consistent grounding in scientific evidence. Among these are the optimum dose and duration of treatment with oral antibiotics that can be given without inducing bacterial resistance, and the safety of oral isotretinoin.
authors.affiliation: Universidade Federal de São Paulo, Brazil. carolinescosta2@terra.com.br
authors.forename: Caroline Sousa
authors.initials: CS
authors.lastname: Costa
authors.forename: Edileia
authors.initials: E
authors.lastname: Bagatin
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001585:Benzoyl Peroxide / Q000627:therapeutic use; D003277:Contraceptives, Oral, Combined / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D006801:Humans; D015474:Isotretinoin / Q000627:therapeutic use; D012176:Retinoids / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D003277:Contraceptives, Oral, Combined; D003879:Dermatologic Agents; D012176:Retinoids; D015474:Isotretinoin; D001585:Benzoyl Peroxide
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