title: Left-right asymmetry in neck lymph nodes distribution in patients with bilateral laryngeal cancer.
abstract: OBJECTIVE
  We aimed to examine left-right asymmetry in involved and total neck lymph nodes distribution in patients with bilateral laryngeal cancer in the present study.
  
  
  METHODS
  Forty-six patients with bilateral laryngeal cancer was included the study. The oncologic database of our otorhinolaryngology department was used. The right and left lymph node with and without involvement by cancer cells counts were retrieved from pathological reports.
  
  
  RESULTS
  The numbers of both involved and total neck lymph nodes were significantly higher on right side than on left side for all neck levels in laryngeal malignancies.
  
  
  CONCLUSIONS
  The results of the present study suggest the existence of a left-right asymmetry in neck lymph node distribution and in the neck lymph node distribution involved by laryngeal cancer cells. The stronger cell-mediated immune activity in the left side of humans may be associated with the blocking of the metastatic invasion of cancer cells from laryngeal malignancies in the left body side.
authors.affiliation: Department of Otorhinolaryngology, Ataturk University, Faculty of Medicine, Erzurum, Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Yoruk
authors.forename: Ramazan
authors.initials: R
authors.lastname: Yuksel
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Yuksel
authors.forename: Senol
authors.initials: S
authors.lastname: Dane
mesh_terms: D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D009333:Neck
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