title: Changes in blood coagulation induced by exercise training in young athletic horses.
abstract: Prothrombin Time (PT), Activated Partial Prothrombin Time (APTT), Fibrinogen concentration (Fbg) and Platelet number (Plt) were evaluated in 20 young athletic horses during a training program. A standardized exercise test (SET) was performed every month for three months. The V4 variations (the speed, in m/min, reached at the blood lactate concentration of 4 mmol/l) obtained for each test were calculated to assess the effect of training program on athletic performance. Blood samples were collected at 20-day intervals over a period of 80 days from the beginning of the training program. The V4 (P < 0.001), PT (P < 0.001), APTT (P < 0.01), Fbg (P < 0.01) and Plt (P < 0.001) varied throughout the training period showing that the modifications of clotting mechanism in response to training period may be considered as a normal physiological response of the hemostatic system to training exercise.
authors.affiliation: Dipartimento di Scienze Sperimentali e Biotecnologie Applicate, Laboratorio di Fisiologia Comparata dell'Esercizio Fisico, Facoltà di Medicina Veterinaria, Università degli Studi di Messina, Polo Universitario Annunziata, 98168 Messina, Italy. Electronic address: aassenza@unime.it.
authors.forename: A
authors.initials: A
authors.lastname: Assenza
authors.forename: F
authors.initials: F
authors.lastname: Tosto
authors.forename: S
authors.initials: S
authors.lastname: Casella
authors.forename: F
authors.initials: F
authors.lastname: Fazio
authors.forename: C
authors.initials: C
authors.lastname: Giannetto
authors.forename: G
authors.initials: G
authors.lastname: Piccione
mesh_terms: D000818:Animals; D001777:Blood Coagulation / Q000502:physiology*; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006736:Horses / Q000097:blood* / Q000502:physiology; D007773:Lactates / Q000097:blood; D008297:Male; D010314:Partial Thromboplastin Time; D010805:Physical Conditioning, Animal; D010976:Platelet Count / Q000662:veterinary; D011517:Prothrombin Time / Q000662:veterinary
chemical_list: D007773:Lactates; D005340:Fibrinogen
keywords: Athletic horse; Blood coagulation; Clotting parameters; Exercise training; SET