title: Enteric pathogens in HIV infected and HIV uninfected individuals with diarrhea in Pune.
abstract: BACKGROUND
  Diarrhea in HIV infected individuals is a common complication seen in about 90% of patients in developing countries. The objective of this study was to identify enteric pathogens in HIV infected and HIV uninfected individuals in Pune.
  
  
  METHODS
  This study was conducted from January 2009 to May 2010 on 331 consecutive patients presenting with diarrhea admitted at Naidu Municipal Corporation Hospital, Pune and processed using conventional methods.
  
  
  RESULTS
  Intestinal parasitic pathogens were detected in 60% (39/65) of HIV infected and 14.3 (38/266) of HIV uninfected individuals. Bacterial pathogens were detected in 34% (22/65) of HIV infected individuals and 28.2% (75/266) of the HIV uninfected individuals. The common enteric pathogens detected in HIV infected individuals were Cystoisospora belli (28%, 18/65) followed by Cryprotosporidium parvum (12%, 8/65). In HIV uninfected individuals Entamoeba histolytica (7.1%, 19/266) followed by Shigella flexnari (4.9%, 13/266) were the most common pathogens. The difference in detection of enteric parasites in HIV infected individuals and HIV uninfected individuals was found to be significant (p < 0.01).
  
  
  CONCLUSIONS
  Intestinal parasitic pathogens are more common in HIV infected antiretroviral therapy naïve patients. Early detection of enteric pathogens by routine examination of stool samples will help in the management and to improve the quality of life for HIV infected individuals.
authors.affiliation: Department of Microbiology & Clinical Pathology, National AIDS Research Institute, Pune, India.
authors.forename: Sangeeta
authors.initials: S
authors.lastname: Kulkarni
authors.forename: Sudhir
authors.initials: S
authors.lastname: Patsute
authors.forename: Suvarna
authors.initials: S
authors.lastname: Sane
authors.forename: Madhuri
authors.initials: M
authors.lastname: Chandane
authors.forename: Pallavi
authors.initials: P
authors.lastname: Vidhate
authors.forename: Arun
authors.initials: A
authors.lastname: Risbud
mesh_terms: D000293:Adolescent; D000328:Adult; D003967:Diarrhea / Q000453:epidemiology / Q000382:microbiology* / Q000469:parasitology*; D005243:Feces / Q000382:microbiology* / Q000469:parasitology*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007194:India / Q000453:epidemiology; D007411:Intestinal Diseases, Parasitic / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D055815:Young Adult
keywords: Diarrhea; Enteric pathogens; HIV infected individuals