title: Fundamental differences between wildlife and biomedical research.
abstract: Non-human animals have starred in countless productions of biological research. Whether they play the lead or supporting role depends on the nature of the investigation. These differences in the roles of animals affect nearly every facet of animal involvement, including: the choice of species, the sample size, the source of individuals, and the settings in which the animals are used. These roles establish different baselines for animal use that require substantially different ethical considerations. Efficient and appropriate oversight of wildlife research benefits the animals and their investigators. Toward that end, Institutional Animal Care and Use Committee (IACUCs) must appreciate the profound differences between biomedical and wildlife research and recognize the value of the state and federal permitting processes required for wildlife studies. These processes assure us that potential impacts beyond the level of the individual are minimal or are justified. Most importantly, IACUCs must recognize that they, and their investigators, have an obligation to use appropriate guidelines for evaluating wildlife research.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Sikes
authors.forename: Ellen
authors.initials: E
authors.lastname: Paul
mesh_terms: D035661:Animal Care Committees / Q000639:trends*; D000827:Animal Welfare / Q000941:ethics*; D000818:Animals; D000830:Animals, Laboratory; D000835:Animals, Wild; D004463:Ecology / Q000941:ethics* / Q000379:methods; D033161:Government Regulation; D006801:Humans; D012106:Research; D015046:Zoology / Q000941:ethics* / Q000379:methods
keywords: IACUC; animal models; animal use; biomedical research; wildlife research