title: [Characteristics of 200 patients with suspected implant allergy compared to 100 symptom-free arthroplasty patients].
abstract: BACKGROUND
  Data on implant allergies are incomplete; therefore, we compared the data on allergy history, patch test (PT) and lymphocyte transformation test (LTT) results in a patient series from the Munich implant allergy outpatient department with symptom-free arthroplasty patients.
  
  
  METHODS
  In this study 200 arthroplasty patients with complaints involving the prosthesis (130 female, 187 knee and 13 hip prostheses) and in parallel 100 symptom-free patients (75 female, 47 knee and 53 hip prostheses) were investigated. A questionnaire-aided history including implant type, cementing, intolerance of dental materials, atopy, cutaneous metal intolerance (CMI) and PT, including a standard series with Ni, Co, Cr, seven bone cement components, including gentamicin and benzoyl peroxide and LTT for Ni, Co and Cr.
  
  
  RESULTS
  In the knee arthroplasty patients with complaints 9.1% showed dental material intolerance, 23.5% atopy, 25.7% CMI, 18.2% metal allergies, 7.4% gentamicin allergy and 27.8% positive metal LTT (mostly to Ni). In symptom-free patients 0% showed dental material intolerance, 19.1% atopy, 12.8% CMI, 12.8% metal allergy, 0% gentamicin allergy and 17% positive metal LTT.
  
  
  CONCLUSIONS
  Characteristics of the patients with complaints were increased intolerance of dental materials, higher rates of atopy, CMI, metal and gentamicin allergy and LTT reactivity.
authors.affiliation: Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum der Ludwig-Maximilians-Universität München, Frauenlobstr. 9-11, 80337, München, Deutschland. Peter.Thomas@med.uni-muenchen.de
authors.forename: P
authors.initials: P
authors.lastname: Thomas
authors.forename: K
authors.initials: K
authors.lastname: Stauner
authors.forename: A
authors.initials: A
authors.lastname: Schraml
authors.forename: V
authors.initials: V
authors.lastname: Mahler
authors.forename: I J
authors.initials: IJ
authors.lastname: Banke
authors.forename: H
authors.initials: H
authors.lastname: Gollwitzer
authors.forename: R
authors.initials: R
authors.lastname: Burgkart
authors.forename: P M
authors.initials: PM
authors.lastname: Prodinger
authors.forename: S
authors.initials: S
authors.lastname: Schneider
authors.forename: M
authors.initials: M
authors.lastname: Pritschet
authors.forename: F
authors.initials: F
authors.lastname: Mazoochian
authors.forename: C
authors.initials: C
authors.lastname: Schopf
authors.forename: A
authors.initials: A
authors.lastname: Steinmann
authors.forename: B
authors.initials: B
authors.lastname: Summer
mesh_terms: D000328:Adult; D001178:Arthroplasty / Q000295:instrumentation / Q000706:statistics & numerical data*; D001843:Bone Cements; D005260:Female; D005839:Gentamicins; D005858:Germany / Q000453:epidemiology; D006622:Hip Prosthesis / Q000706:statistics & numerical data*; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000453:epidemiology*; D007595:Joint Prosthesis; D007720:Knee Prosthesis / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors
chemical_list: D001843:Bone Cements; D005839:Gentamicins
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