title: Necrolytic migratory erythema and glucagonoma rising from pancreatic head.
abstract: Glucagonoma syndrome encompasses necrolytic migratory erythema (NME), hyperglucagonemia, diabetes mellitus, anemia, weight loss, glossitis, angular cheilitis, steatorrhea, diarrhea, venous thrombosis, and neuropsychiatric disturbance. Of all the symptoms, NME is a rare skin disorder which is pathognomonic for glucagonoma. We present a 61-year-old woman diagnosed initially as pancreatic head adenocarcinoma with liver metastasis prior to the skin eruption. From the dermatologic finding and other clues, glucagonoma was diagnosed finally.
authors.affiliation: Department of Dermatology, Chang Gung Memorial Hospital - Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
authors.forename: Han-Chi
authors.initials: HC
authors.lastname: Tseng
authors.forename: Chien-Ting
authors.initials: CT
authors.lastname: Liu
authors.forename: Ji-Chen
authors.initials: JC
authors.lastname: Ho
authors.forename: Shang-Hong
authors.initials: SH
authors.lastname: Lin
mesh_terms: D005260:Female; D005935:Glucagonoma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008875:Middle Aged; D058568:Necrolytic Migratory Erythema / Q000175:diagnosis* / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000175:diagnosis*
keywords: Glucagonoma; Glucagonoma syndrome; Necrolytic migratory erythema; Pancreatic head; Pancreatic neuroendocrine tumor