title: [Endoscopic variceal ligation in prevention from esophageal variceal hemorrhage of advanced schistosomiasis patients].
abstract: OBJECTIVE
  To evaluate the effect of the endoscopic esophageal variceal ligation on the prevention from recurrence of esophageal varices and variceal hemorrhage.
  
  
  METHODS
  Forty-two advanced schistosomiasis patients with variceal hemorrhage in the treatment group received the endoscopic esophageal variceal ligation, and 30 patients in the control group did not, and all of them had oral propranolol, spironolactone and 5 single-isosorbide dinitrate etc. in hospital for the same period and had these drugs for 3-6 months after discharge. The re-examinations of endoscopy were performed once 3 to 6 months.
  
  
  RESULTS
  The time of follow-up was from 2 to 3 years and the average was 29 months. In the treatment group, the rate of recurrence of esophageal varices was 19.0% (8/42) and the average time was 30 months; the incidence of esophageal variceal bleeding was 11.9% (5/42) and 2 patients died. In the control group, the rate of recurrence of esophageal varices was 43.3% (13/30) and the average time was 18 months; the incidence of esophageal variceal bleeding was 36.7% (11/30) and 7 patients died. The therapeutic efficacy of the treatment group was much superior to that of the control group.
  
  
  CONCLUSIONS
  The endoscopic esophageal variceal ligation is effective and safe, and can become one of the preferred methods in the prevention from variceal hemorrhage.
authors.affiliation: Third People' s Hospital of Jingzhou City, Hubei Province, Jingzhou 434001, China.
authors.forename: Lie-Quan
authors.initials: LQ
authors.lastname: Liu
authors.forename: Zhang-Yu
authors.initials: ZY
authors.lastname: Zhou
authors.forename: Zheng-Mei
authors.initials: ZM
authors.lastname: Wan
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Yue-Xiao
authors.initials: YX
authors.lastname: Tian
authors.forename: Heng
authors.initials: H
authors.lastname: Hu
mesh_terms: D000328:Adult; D000368:Aged; D004724:Endoscopy / Q000379:methods; D004932:Esophageal and Gastric Varices / Q000469:parasitology / Q000517:prevention & control* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006471:Gastrointestinal Hemorrhage / Q000469:parasitology / Q000517:prevention & control* / Q000601:surgery; D006801:Humans; D008026:Ligation / Q000379:methods; D008297:Male; D008875:Middle Aged; D012552:Schistosomiasis / Q000150:complications* / Q000601:surgery; D055502:Secondary Prevention; D055815:Young Adult