title: Impact of psychological screening on routine outpatient care of hematopoietic cell transplantation survivors.
abstract: Hematopoietic cell transplantation recipients are at high risk for psychological distress, with reported prevalence rates as high as 40%. Although published guidelines advocate periodic routine screening, it is unclear how screening affects management of psychological symptoms at routine post-HCT outpatient clinic visits. We hypothesized that providers will be more likely to act on patients' psychological symptoms if a screening survey is completed and reviewed before a clinic visit. We used a brief, diagnostically focused Patient Health Questionnaire (PHQ), to assess for depressive disorders, anxiety, substance abuse, and problems in occupational or interpersonal functioning (functional disruption). Adult HCT survivors were randomized to complete the PHQ before meeting with their medical provider (n = 50; experimental group) or afterwards (n = 51; control group). Providers used the experimental group PHQ results at their discretion during the visits. Both providers and patients rated their satisfaction with management of psychological concerns after the visit. The prevalence of clinically significant depression (21%), anxiety (14%), or suicidal ideation (8%) did not differ between the 2 groups. Patients in the experimental group were significantly more likely to have discussion of psychological symptoms than the control group (68% versus 49%, P = .05). Medical providers were significantly more satisfied with the management of psychological issues for the experimental group (P < .001). Patients with depression or anxiety were significantly more likely to prefer the PHQ be used at future visits (P = .02 and P = .001, respectively). These findings suggest an informative yet brief self-report psychological screen can be easily integrated into routine care of hematopoietic cell transplantation survivors, stimulates discussion of psychological symptoms, and improves provider satisfaction with psychological symptom management. Future research will evaluate whether serial prospective administration improves patient outcomes.
authors.affiliation: Department of Psychiatry, University of Michigan, Ann Arbor, Michigan; Department of Psychology, Eastern Michigan University, Ypsilanti, Michigan. Electronic address: fhoodin@emich.edu.
authors.forename: Flora
authors.initials: F
authors.lastname: Hoodin
authors.forename: Lili
authors.initials: L
authors.lastname: Zhao
authors.forename: Jillian
authors.initials: J
authors.lastname: Carey
authors.forename: John E
authors.initials: JE
authors.lastname: Levine
authors.forename: Carrie
authors.initials: C
authors.lastname: Kitko
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis; D055088:Early Detection of Cancer; D005260:Female; D019337:Hematologic Neoplasms / Q000523:psychology / Q000601:surgery; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011594:Psychometrics / Q000379:methods*; D011788:Quality of Life; D017741:Survivors / Q000523:psychology*; D019172:Transplantation Conditioning / Q000379:methods / Q000523:psychology*; D055815:Young Adult
keywords: Cancer survivorship; Depression; Hematopoietic stem cell transplantation; Psychological; Screening
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