title: A rare association of leiomyosarcoma with squamous cell carcinoma of the larynx: two cases.
abstract: OBJECTIVE
  To discuss the histopathogenesis and treatment choices for synchronous tumours of the larynx.
  
  
  METHODS
  We present two cases of synchronous laryngeal leiomyosarcoma and squamous cell carcinoma. The first case was an early-stage tumour and the second an advanced-stage tumour of the larynx. Selection of adequate treatment for synchronous tumours is difficult because of different spreading rates and metastatic patterns. Treatment choices for both the primary tumour site and the neck should be related to the stage of the squamous component of the tumour.
  
  
  CONCLUSIONS
  In such cases, the tumour location, tumour stage and lymphatic metastases must be carefully evaluated in order to make the optimum treatment choice. Treatment evaluation of the neck should be related to the stage of the squamous component of these synchronous tumours. Partial laryngectomy techniques may be preferred if the extent of the disease permits.
authors.affiliation: Department of Otolaryngology, Ministry of Health, Kozan State Hospital, Adana, Turkey. dremrahkara@gmail.com
authors.forename: E
authors.initials: E
authors.lastname: Kara
authors.forename: M F
authors.initials: MF
authors.lastname: Cetik
authors.forename: U
authors.initials: U
authors.lastname: Tuncer
authors.forename: A
authors.initials: A
authors.lastname: Uguz
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary; D011859:Radiography; D016896:Treatment Outcome