title: Amrinone, forerunner of novel cardiotonic agents, caused paradigm shift of heart failure pharmacotherapy.
authors.affiliation: Department of Pharmacology, Yamagata University School of Medicine, Yamagata, Japan. mendou@med.id.yamagata-u.ac.jp
authors.forename: Masao
authors.initials: M
authors.lastname: Endoh
mesh_terms: D000676:Amrinone / Q000494:pharmacology / Q000627:therapeutic use*; D000818:Animals; D020013:Calcium Signaling / Q000502:physiology; D002316:Cardiotonic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002908:Chronic Disease; D004195:Disease Models, Animal; D004285:Dogs; D004358:Drug Therapy / Q000639:trends*; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D058987:Phosphodiesterase 3 Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D014664:Vasodilation / Q000187:drug effects / Q000502:physiology
chemical_list: D002316:Cardiotonic Agents; D058987:Phosphodiesterase 3 Inhibitors; D000676:Amrinone