title: Poly(ether-ether-ketone) orthopedic bearing surface modified by self-initiated surface grafting of poly(2-methacryloyloxyethyl phosphorylcholine).
abstract: We investigated the production of free radicals on a poly(ether-ether-ketone) (PEEK) substrate under ultraviolet (UV) irradiation. The amount of the ketyl radicals produced from the benzophenone (BP) units in the PEEK molecular structure initially increased rapidly and then became almost constant. Our observations revealed that the BP units in PEEK acted as photoinitiators, and that it was possible to use them to control the graft polymerization of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC). This "self-initiated surface graft polymerization" method is very convenient in the absence of external photoinitiator. We also investigated the effects of the monomer concentration and UV irradiation time on the extent of the grafted PMPC layer. Furthermore, as an application to improving the durability of artificial hips, we demonstrated the nanometer-scale photoinduced grafting of PMPC onto PEEK and carbon fiber-reinforced PEEK (CFR-PEEK) orthopedic bearing surfaces and interfaces. A variety of test revealed significant improvements in the water wettability, frictional properties, and wear resistance of the surfaces and interfaces.
authors.affiliation: Department of Materials Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kyomoto
authors.forename: Toru
authors.initials: T
authors.lastname: Moro
authors.forename: Shihori
authors.initials: S
authors.lastname: Yamane
authors.forename: Masami
authors.initials: M
authors.lastname: Hashimoto
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Takatori
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Ishihara
mesh_terms: D001577:Benzophenones / Q000737:chemistry; D018786:Bone Substitutes / Q000737:chemistry* / Q000528:radiation effects; D002244:Carbon / Q000737:chemistry; D000077482:Carbon Fiber; D005609:Free Radicals / Q000737:chemistry; D017276:Friction / Q000528:radiation effects; D006622:Hip Prosthesis; D007659:Ketones / Q000737:chemistry*; D008422:Materials Testing; D018625:Microscopy, Atomic Force; D046529:Microscopy, Electron, Transmission; D009985:Orthopedics; D010767:Phosphorylcholine / Q000031:analogs & derivatives* / Q000737:chemistry; D011092:Polyethylene Glycols / Q000737:chemistry*; D058105:Polymerization; D011108:Polymers; D011109:Polymethacrylic Acids / Q000737:chemistry*; D013314:Stress, Mechanical; D013499:Surface Properties / Q000528:radiation effects; D014466:Ultraviolet Rays; D017155:Wettability / Q000528:radiation effects
chemical_list: D001577:Benzophenones; D018786:Bone Substitutes; D000077482:Carbon Fiber; D005609:Free Radicals; D007659:Ketones; D011108:Polymers; D011109:Polymethacrylic Acids; C115766:poly(2-methacryloyloxyethyl-phosphorylcholine); D010767:Phosphorylcholine; C063834:polyetheretherketone; D011092:Polyethylene Glycols; C047723:benzophenone; D002244:Carbon
keywords: Joint replacement; Phosphorylcholine; Photopolymerization; Poly(ether-ether-ketone); Surface modification; Wear mechanism