title: Benign-onset acute disseminated encephalomyelitis: a report on two cases.
abstract: The signs and symptoms of acute disseminated encephalomyelitis are heterogeneous and dependent on the location and severity of the inflammatory process. The meningoencephalitic presentation may include meningism, impaired consciousness (occasionally leading to coma), seizures and confusion, or behavioral disturbances. Multifocal neurological features include a combination of optic neuritis, visual field defects, cranial neuropathy, sensorimotor impairment, ataxia, aphasia, and involuntary movements. One definition of acute disseminated encephalomyelitis is "an initial clinical event with a presumed inflammatory and demyelinating cause, with acute or sub-acute onset affecting multifocal areas of the central nervous system". Patients with acute disseminated encephalomyelitis frequently suffer from seizures, disturbances of consciousness, fever, and headaches, and occasionally there are focal signs and symptoms. Here, we report on two cases who presented with different symptoms, but the clinical findings that the patients showed were benign.
authors.affiliation: Pamukkale University, Faculty of Medicine, Neurology Department, Denizli, Turkey. eylemteke@yahoo.com
authors.forename: Eylem
authors.initials: E
authors.lastname: Degirmenci
authors.forename: Cagdas
authors.initials: C
authors.lastname: Erdogan
authors.forename: Attila
authors.initials: A
authors.lastname: Oguzhanoglu
authors.forename: Levent Sinan
authors.initials: LS
authors.lastname: Bir
mesh_terms: D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001921:Brain / Q000473:pathology*; D003287:Contrast Media; D003937:Diagnosis, Differential; D004673:Encephalomyelitis, Acute Disseminated / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D004751:Enteritis / Q000150:complications; D005260:Female; D005682:Gadolinium; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D018908:Muscle Weakness / Q000209:etiology; D010612:Pharyngitis / Q000150:complications; D013064:Speech Disorders / Q000209:etiology; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D003287:Contrast Media; D005682:Gadolinium; D008775:Methylprednisolone