title: Feasibility of single-beat full-volume capture real-time three-dimensional echocardiography for quantification of right ventricular volume: validation by cardiac magnetic resonance imaging.
abstract: BACKGROUND
  The lack of an accurate noninvasive method for assessing right ventricular (RV) volume and function has been a major deficiency of two-dimensional (2D) echocardiography. The aim of our study was to test the feasibility of single-beat full-volume capture with real-time three-dimensional echo (3DE) imaging system for the evaluation of RV volumes and function validated by cardiac magnetic resonance imaging (CMRI).
  
  
  METHODS
  Sixty-one subjects (16 normal subjects, 20 patients with hypertension, 16 patients with pulmonary heart disease and 9 patients with coronary heart disease) were studied. RV volume and function assessments using 3DE were compared with manual tracing with CMRI as the reference method.
  
  
  RESULTS
  Fifty-nine of 61 patients (96.7%; 36 male, mean age, 62 ± 15 years) had adequate three-dimensional echocardiographic data sets for analysis. The mean RV end diastolic volume (EDV) was 105 ± 38 ml, end-systolic volume (ESV) was 60 ± 30 and RV ejection fraction (EF) was 44 ± 11% by CMRI; and EDV 103 ± 38 ml, ESV 60 ± 28 ml and RV EF 41 ± 13% by 3DE. The correlations and agreements between measurements estimated by two methods were acceptable.
  
  
  CONCLUSIONS
  RV volumes and function can be analyzed with 3DE software in most of subjects with or without heart diseases, which is able to be estimated with single-beat full-volume capture with real-time 3DE compared with CMRI.
authors.affiliation: Department of Ultrasound, General Hospital of Tai Gang, Shanxi Medical University, PR China.
authors.forename: Quan Bin
authors.initials: QB
authors.lastname: Zhang
authors.forename: Jing Ping
authors.initials: JP
authors.lastname: Sun
authors.forename: Rui Feng
authors.initials: RF
authors.lastname: Gao
authors.forename: Alex Pui-Wai
authors.initials: AP
authors.lastname: Lee
authors.forename: Yan Lin
authors.initials: YL
authors.lastname: Feng
authors.forename: Xiao Rong
authors.initials: XR
authors.lastname: Liu
authors.forename: Wei
authors.initials: W
authors.lastname: Sheng
authors.forename: Feng
authors.initials: F
authors.lastname: Liu
authors.forename: Xing Sheng
authors.initials: XS
authors.lastname: Yang
authors.forename: Fang
authors.initials: F
authors.lastname: Fang
authors.forename: Cheuk-Man
authors.initials: CM
authors.lastname: Yu
mesh_terms: D000368:Aged; D003199:Computer Systems / Q000592:standards*; D019560:Echocardiography, Three-Dimensional / Q000592:standards*; D005240:Feasibility Studies; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000378:metabolism*; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine / Q000592:standards*; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume / Q000502:physiology*
keywords: RV volume; Real time 3D; Right ventricular function