title: Pulmonary hypertension after hematopoietic stem cell transplantation.
abstract: Pulmonary hypertension (PH) is a potentially fatal complication of hematopoietic stem cell transplantation (HSCT). Given its nonspecific clinical presentation, it is likely that this clinical entity is underdiagnosed after HSCT. Data describing the incidence, risk factors, and etiology of PH in HSCT recipients are minimal. Physicians caring for HSCT recipients should be aware of this severe post-transplant complication because timely diagnosis and treatment may allow improved clinical outcomes. We summarize the pathophysiology, clinical presentation, diagnosis, and management of PH in HSCT recipients.
authors.affiliation: Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Electronic address: christopher.dandoy@cchmc.org.
authors.forename: Christopher E
authors.initials: CE
authors.lastname: Dandoy
authors.forename: Russel
authors.initials: R
authors.lastname: Hirsch
authors.forename: Ranjit
authors.initials: R
authors.lastname: Chima
authors.forename: Stella M
authors.initials: SM
authors.lastname: Davies
authors.forename: Sonata
authors.initials: S
authors.lastname: Jodele
mesh_terms: D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology*; D012307:Risk Factors; D019172:Transplantation Conditioning / Q000009:adverse effects; D014182:Transplantation, Autologous
keywords: Pulmonary arterial hypertension; Pulmonary hypertension; Pulmonary veno-occlusive disease; Thrombotic microangiopathy