title: Temporal variation of breast cancer surgical treatment in a university hospital in Brazil's Central West region.
abstract: OBJECTIVE
  To assess the types of surgical treatments for breast cancer performed by the Mastology program of the Clinics Hospital, Federal University of Goiás (HC-UFG).
  
  
  METHODS
  We conducted a cross-sectional, cohort study on the breast operations performed at HC-UFG from January 2002 to December 2009. We evaluated the surgical records for: surgical time and size, surgeon, type of operation, diagnosis, and type of anesthesia. The medical charts were researched for: pathology report of the tumor, lymph node involvement, primary tumor size, staging and performance of neoadjuvant therapies. We excluded operations for the removal of benign breast tumors. The temporal variation was analyzed using Poisson regression, considering the annual percentage change (APC).
  
  
  RESULTS
  403 operations were performed for breast cancer during the study period, with an average of 50.38 operations per year. The most common histological type was invasive ductal carcinoma (72.6%). The mean age of patients was 52 years, and 29% had disease in stages III and IV. The temporal trend revealed a significant increase in tumor size (p <0.01), the clinical stages III and IV (p = 0.01) and the use of neoadjuvant chemotherapy (p = 0.02). There was increase in mastectomies (APC = 9 cases/year, p = .04). There was no increase in cases of breast conservation treatments or of mastectomies with immediate reconstruction.
  
  
  CONCLUSIONS
  In recent years, the HC-UFG has had an increased number of mastectomies as a result of increased incidence of locoregionally advanced breast cancer.
authors.affiliation: Faculdade de Medicina, Universidade Federal de Goiás-UFGO, Goiânia, Goiás State, Brazil. ruffojr@terra.com.br
authors.forename: Ruffo
authors.initials: R
authors.lastname: Freitas
authors.forename: Liza Batista
authors.initials: LB
authors.lastname: Siqueira
authors.forename: Eduardo Nazareno dos Anjos
authors.initials: EN
authors.lastname: Carrijo
authors.forename: Roberta Pinter
authors.initials: RP
authors.lastname: Lacerda
authors.forename: Régis Resende
authors.initials: RR
authors.lastname: Paulinelli
authors.forename: Rosemar Macedo Sousa
authors.initials: RM
authors.lastname: Rahal
authors.forename: Luis Fernando Pádua
authors.initials: LF
authors.lastname: Oliveira
mesh_terms: D001938:Brazil; D001943:Breast Neoplasms / Q000601:surgery*; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D006785:Hospitals, University; D006801:Humans; D008408:Mastectomy / Q000379:methods* / Q000639:trends*; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors