title: Basidiobolomycosis a mysterious fungal infection mimic small intestinal and colonic tumour with renal insufficiency and ominous outcome.
abstract: Basidiobolomycosis is a rare fungal infection caused by Basidiobolus ranarum a worldwide environmental saprophyte fungus that is potentially a pathogen. B ranarum mainly affects the subcutaneous tissues but gastrointestinal and disseminated infections rarely have been reported previously. We report a case of B ranarum infection in a 12-year-old immunocompetent boy presented with abdominal pain from 2 months earlier before admission in the hospital. Abdominal CT scan revealed a lobulated mass-like lesion in the vicinity of right lower quadrant enveloping ascending colon and terminal ileum with involvement of mesentery. Histopathological examination showed severe full-thickness infiltration of inflammatory cells mainly eosinophils admixed with multinucleated giant cells and large areas of necrosis with granulomatous feature. Periodic acid Schiff staining demonstrated thin-walled septate fungal hyphae's surrounded by eosinophilic material (Splendore-Hoppeli phenomenon) identified as a basidiobolomycosis.
authors.affiliation: Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd, Islamic Republic of Iran. shokouh_zahir@yahoo.com
authors.forename: Shokouh Taghipour
authors.initials: ST
authors.lastname: Zahir
authors.forename: Naser Sefidrokh
authors.initials: NS
authors.lastname: Sharahjin
authors.forename: Saeed
authors.initials: S
authors.lastname: Kargar
mesh_terms: D015746:Abdominal Pain / Q000382:microbiology; D002648:Child; D003110:Colonic Neoplasms / Q000175:diagnosis; D003937:Diagnosis, Differential; D020091:Entomophthorales; D017809:Fatal Outcome; D006801:Humans; D007078:Ileal Neoplasms / Q000175:diagnosis*; D007411:Intestinal Diseases, Parasitic / Q000175:diagnosis*; D008297:Male; D051437:Renal Insufficiency / Q000382:microbiology*; D020096:Zygomycosis / Q000150:complications / Q000175:diagnosis*
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