title: Characterization of ultrananocrystalline diamond microsensors forin vivodopamine detection.
abstract: We show the technical feasibility of coating and micro patterning boron-doped ultrananocrystalline diamond (UNCD®) on metal microwires and of applying them as microsensors for the detection of dopaminein vivousing fast-scan cyclic voltammetry. UNCD electrode surface consistently generated electrochemical signals with high signal-to-noise ratio of >800 using potassium ferrocyanide-ferricyanide redox couple. Parylene patterned UNCD microelectrodes were effectively applied to detect dopamine reliablyin vitrousing flow injection analysis with a detection limit of 27 nM and in the striatum of the anesthetized rat during electrical stimulation of dopamine neurons.
authors.affiliation: Advanced Diamond Technologies, Inc., 48 E Belmont Drive, Romeoville, Illinois 60446, USA.
authors.forename: Prabhu U
authors.initials: PU
authors.lastname: Arumugam
authors.forename: Hongjun
authors.initials: H
authors.lastname: Zeng
authors.forename: Shabnam
authors.initials: S
authors.lastname: Siddiqui
authors.forename: Dan P
authors.initials: DP
authors.lastname: Covey
authors.forename: John A
authors.initials: JA
authors.lastname: Carlisle
authors.forename: Paul A
authors.initials: PA
authors.lastname: Garris
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