title: Breast osteosarcoma 29 years after radiation therapy for epithelial breast cancer.
abstract: Radiation therapy has a solid role in the management of breast adenocarcinoma. It significantly reduces the rates of disease recurrence. Nevertheless, radiation therapy is not without side effects and patients who have undergone breast irradiation are at increased risk for lung disease, sarcomas, acute leukemia and esophageal cancer. We present a case of radiation-induced breast osteosarcoma 29 years after radiation therapy and lumpectomy for breast adenocarcinoma. The patient had several disease recurrences after surgical resection and was found to have pulmonary metastases.
authors.affiliation: Saint Joseph Hospital, Department of Internal Medicine, Chicago, Ill., USA.
authors.forename: Nwabundo
authors.initials: N
authors.lastname: Nwankwo
authors.forename: Aram
authors.initials: A
authors.lastname: Barbaryan
authors.forename: Alaa M
authors.initials: AM
authors.lastname: Ali
authors.forename: Nasir
authors.initials: N
authors.lastname: Hussain
authors.forename: Raya
authors.initials: R
authors.lastname: Saba
authors.forename: Suartcha
authors.initials: S
authors.lastname: Prueksaritanond
authors.forename: Aibek E
authors.initials: AE
authors.lastname: Mirrakhimov
authors.forename: Teresita
authors.initials: T
authors.lastname: Zdunek
authors.forename: Nora
authors.initials: N
authors.lastname: Bucher
keywords: Breast osteosarcoma; Epithelial breast cancer; Radiation therapy
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