title: A simple meningococcal sepsis prognostic score: focusing on the human animal.
abstract: A simple cheap meningococcal sepsis prognostic score based on readily available, rapid, objective laboratory base excess and platelet count was developed and validated retrospectively. This BEP score should facilitate sepsis clinical trials, allowing study of the relevant human animal model.
authors.forename: Paula
authors.initials: P
authors.lastname: Holinski
authors.forename: Ari R
authors.initials: AR
authors.lastname: Joffe
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008589:Meningococcal Infections / Q000097:blood* / Q000401:mortality*; D018805:Sepsis / Q000097:blood* / Q000401:mortality*; D012720:Severity of Illness Index
references.citation: Nature. 2012 Sep 6;489(7414):52-5
references.pmid: 22955614
references.citation: Crit Care Med. 2009 Jan;37(1 Suppl):S30-7
references.pmid: 19104223
references.citation: Proc Natl Acad Sci U S A. 2008 May 13;105(19):6987-92
references.pmid: 18458337
references.citation: Crit Care. 2013 Apr 11;17(2):R68
references.pmid: 23577792
references.citation: Lancet. 2007 Mar 10;369(9564):836-843
references.pmid: 17350452
references.citation: BMJ. 2005 Jun 25;330(7506):1475
references.pmid: 15976421
references.citation: Lancet. 2012 Apr 21;379(9825):1551-9
references.pmid: 22516561
references.citation: Nat Rev Drug Discov. 2003 Feb;2(2):151-4
references.pmid: 12563306
references.citation: Nature. 2011 Oct 19;478(7369):343-8
references.pmid: 22012392
references.citation: J Infect Dis. 2010 Jan 15;201(2):223-32
references.pmid: 20001600
references.citation: Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3507-12
references.pmid: 23401516
references.citation: Lancet. 2000 Sep 16;356(9234):961-7
references.pmid: 11041396
references.citation: EMBO Rep. 2004 Nov;5(11):1016-20
references.pmid: 15520799