title: Antifungal susceptibility of emerging opportunistic yeasts and yeast-like fungi from Rhea americana.
abstract: Opportunistic yeasts and yeast-like fungi have been recognized as important pathogens in high-risk patients. This study aimed to evaluate the presence of these microorganisms in the microbiota of captive rheas and to investigate the antifungal susceptibility of the isolated strains. Isolates representing Magnusiomyces capitatus (Geotrichum capitatum, n = 11), Trichosporon mucoides (n = 11), Trichosporon asteroides (n = 5), Rhodotorula mucilaginosa (n = 4), Trichosporon asahii (n = 3), Trichosporon cutaneum (n = 3), and Trichosporon ovoides (n = 3) were obtained from the oropharynx, cloaca, and feces of 58 animals. Most of the isolates were susceptible to antifungals in vitro; however, resistance against fluconazole (n = 1) and itraconazole (n = 2) was detected among T. mucoides. This study indicates that healthy rheas can be reservoirs of opportunistic pathogens. Primary resistance to azoles in T. mucoides obtained from these animals demonstrates the potential risk to humans.
authors.affiliation: Department of Pathology and Legal Medicine, School of Medicine, Specialized Medical Mycology Center, Postgraduate Program in Medical Microbiology, Federal University of Ceará, Rua Coronel Nunes de Melo, 1315 CEP: 60430-270 Fortaleza, CE, Brazil. rossanacordeiro@ufc.br
authors.forename: Rossana
authors.initials: R
authors.lastname: de Aguiar Cordeiro
authors.forename: Lucas
authors.initials: L
authors.lastname: Pereira de Alencar
authors.forename: Raimunda Sâmia
authors.initials: RS
authors.lastname: Nogueira Brilhante
authors.forename: Débora
authors.initials: D
authors.lastname: de Souza Collares Maia Castelo-Branco
authors.forename: Carlos Eduardo
authors.initials: CE
authors.lastname: Cordeiro Teixeira
authors.forename: Ramila
authors.initials: R
authors.lastname: de Brito Macedo
authors.forename: Daniel
authors.initials: D
authors.lastname: Teixeira Lima
authors.forename: Manoel
authors.initials: M
authors.lastname: Paiva de Araújo Neto
authors.forename: André
authors.initials: A
authors.lastname: Jalles Monteiro
authors.forename: Nilza
authors.initials: N
authors.lastname: Dutra Alves
authors.forename: Moacir
authors.initials: M
authors.lastname: Franco de Oliveira
authors.forename: José Júlio
authors.initials: JJ
authors.lastname: Costa Sidrim
authors.forename: Marcos Fábio
authors.initials: MF
authors.lastname: Rocha Gadelha
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D025141:Drug Resistance, Fungal; D005658:Fungi / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D020311:Rheiformes / Q000382:microbiology*; D015003:Yeasts / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000935:Antifungal Agents