title: Prevalence of occult hepatitis B virus infection in kidney transplant recipients.
abstract: In this cross-sectional study, 207 hepatitis B surface antigen (HBsAg)-negative kidney transplant recipients were evaluated based on demographic and epidemiological data and on the levels of serological markers of hepatitis B virus (HBV) and hepatitis C virus infection and liver enzymes. Patients with HBV or human immunodeficiency virus infection were excluded. Sera were analysed for the presence of HBV-DNA. HBV-DNA was detected in two patients (1%), indicating occult hepatitis B (OHB) infection (the HBV-DNA loads were 3.1 and 3.5 IU/mL in these patients). The results of the liver function tests were normal and no serological markers indicative of HBV infection were detected. The prevalence of OHB infection was low among kidney transplant recipients, most likely due to the low HBsAg endemicity in the general population of the study area.
authors.affiliation: Departamento de Clínica Médica, Serviço de Hepatologia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. franz.cibele@gmail.com
authors.forename: Cibele
authors.initials: C
authors.lastname: Franz
authors.forename: Renata de Mello
authors.initials: Rde M
authors.lastname: Perez
authors.forename: Mariano Gustavo
authors.initials: MG
authors.lastname: Zalis
authors.forename: Ana Carolina Jonard
authors.initials: AC
authors.lastname: Zalona
authors.forename: Pedro Túlio Monteiro de Castro e Abreu
authors.initials: PT
authors.lastname: Rocha
authors.forename: Renato Torres
authors.initials: RT
authors.lastname: Gonçalves
authors.forename: Letícia Cancella
authors.initials: LC
authors.lastname: Nabuco
authors.forename: Cristiane Alves
authors.initials: CA
authors.lastname: Villela-Nogueira
mesh_terms: D000328:Adult; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006509:Hepatitis B / Q000175:diagnosis / Q000453:epidemiology*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006515:Hepatitis B virus / Q000235:genetics / Q000276:immunology; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D015995:Prevalence
chemical_list: D004279:DNA, Viral; D006514:Hepatitis B Surface Antigens
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