title: Recyclable and stable silver deposited magnetic nanoparticles with poly (vinyl pyrrolidone)-catechol coated iron oxide for antimicrobial activity.
abstract: This paper introduces a facile method to make highly stable and recyclable antimicrobial magnetic nanoparticles (NPs). Initially, magnetic iron oxide nanoparticles (IONPs) were coated with poly (vinyl pyrrolidone) conjugated catechol (PVP-CCDP). Afterward, silver nanoparticles (Ag(0)) were deposited onto PVP-CCDP coated IONPs using remain catechol. The prepared nanoparticles showed long term (~4 weeks) colloidal stability and redispersibility, respectively, against external magnetic field and over a broad range of pH (4-12). The NPs were characterized by UV-vis, SEM, XPS, and XRD measurements. TEM and DLS analyses showed that the mean particle size of PVP-CCDP coated IONPs/Ag(0) were about 72 nm. The recyclable magnetic NPs possessed a high antibacterial effect against the model microbes Staphylococcus aureus and Escherichia coli and could be separated easily using magnet following antibacterial test for repeated uses and maintained 100% antibacterial efficiency during three cycles. In MTT assay, the magnetic nanoparticles possessed no measureable cytotoxicity to live cells.
authors.affiliation: Department of Green Bio Engineering, Korea National University of Transportation, Chungju-Si 380-702, Republic of Korea.
authors.forename: Tamim
authors.initials: T
authors.lastname: Mosaiab
authors.forename: Chan Jin
authors.initials: CJ
authors.lastname: Jeong
authors.forename: Gyo Jic
authors.initials: GJ
authors.lastname: Shin
authors.forename: Kyung Ho
authors.initials: KH
authors.lastname: Choi
authors.forename: Sang Kug
authors.initials: SK
authors.lastname: Lee
authors.forename: Iksoo
authors.initials: I
authors.lastname: Lee
authors.forename: Insik
authors.initials: I
authors.lastname: In
authors.forename: Sung Young
authors.initials: SY
authors.lastname: Park
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology; D002396:Catechols / Q000737:chemistry / Q000494:pharmacology*; D016923:Cell Death / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D020099:Coated Materials, Biocompatible / Q000494:pharmacology; D004285:Dogs; D004926:Escherichia coli / Q000187:drug effects; D005290:Ferric Compounds / Q000737:chemistry*; D061985:Madin Darby Canine Kidney Cells; D060328:Magnetic Phenomena; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008826:Microbial Sensitivity Tests; D010316:Particle Size; D056951:Photoelectron Spectroscopy; D011760:Pyrrolidinones / Q000737:chemistry*; D059027:Recycling; D012834:Silver / Q000494:pharmacology*; D013052:Spectrometry, X-Ray Emission; D013056:Spectrophotometry, Ultraviolet; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D002396:Catechols; D020099:Coated Materials, Biocompatible; D005290:Ferric Compounds; D011760:Pyrrolidinones; C000499:ferric oxide; D012834:Silver; C034221:catechol
keywords: Antimicrobial; Catechol; Iron oxide; Recyclable; Silver nanoparticles