title: Exploring the origin and potential for spread of the 2013 dengue outbreak in Luanda, Angola.
abstract: BACKGROUND
  Dengue in Africa is underreported. Simultaneous reports of travellers with dengue returning from Luanda, Angola, to six countries on four continents suggest that a major dengue outbreak is currently occurring in Angola, South West Africa.
  
  
  METHODS
  To identify the origin of the imported dengue virus, we sequenced the virus from Angola and investigated the interconnectivity via air travel between dengue-endemic countries and Angola.
  
  
  CONCLUSIONS
  Our analyses show that the Angola outbreak was most likely caused by an endemic virus strain that had been circulating in West Africa for many years. We also show that Portugal and South Africa are most likely at the highest risk of importation of dengue from Angola due to the large number of air passengers between Angola and these countries.
authors.affiliation: Program in Emerging Infectious Diseases, Duke-NUS, Singapore. october.sessions@duke-nus.edu.sg
authors.forename: October M
authors.initials: OM
authors.lastname: Sessions
authors.forename: Kamran
authors.initials: K
authors.lastname: Khan
authors.forename: Yan'an
authors.initials: Y
authors.lastname: Hou
authors.forename: Eyal
authors.initials: E
authors.lastname: Meltzer
authors.forename: Mikkel
authors.initials: M
authors.lastname: Quam
authors.forename: Eli
authors.initials: E
authors.lastname: Schwartz
authors.forename: Duane J
authors.initials: DJ
authors.lastname: Gubler
authors.forename: Annelies
authors.initials: A
authors.lastname: Wilder-Smith
mesh_terms: D000810:Angola / Q000453:epidemiology; D003715:Dengue / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D003716:Dengue Virus / Q000235:genetics; D004196:Disease Outbreaks / Q000706:statistics & numerical data*; D005838:Genotype; D006801:Humans; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012307:Risk Factors; D016415:Sequence Alignment; D014195:Travel
keywords: Angola; dengue; dengue in Africa; dengue sequence; international travel
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