title: [Radiculopathy in patients with Heerfordt's syndrome: two case presentations and review of the literature].
abstract: As a subtype of the clinical presentations associated with sarcoidosis, the combination of uveitis, parotid gland swelling, and facial nerve palsy is known as Heerfordt's syndrome. This syndrome is an extremely rare disorder that has been estimated to affect only 4.1-5.6% of patients with sarcoidosis. We present 2 cases of Heerfordt's syndrome associated with radiculopathy in the trunk. The 2 patients experienced unilateral or bilateral radiculopathy in the trunk and in the trigeminal nerve area associated with Heerfordt's syndrome. Radiculopathy is also a rare manifestation in patients with neurosarcoidosis. A literature review revealed that only 51 cases of radiculopathy associated with sarcoidosis have been documented. A diagnosis of Heerfordt's syndrome was observed in 7 out of these 51 cases. Together with our 2 cases, 9 out of 53 patients with radiculopathy associated with sarcoidosis have been diagnosed as having Heerfordt's syndrome (estimated frequency, 16.9%). In conclusion, radiculopathy is a common neurological manifestation in patients with Heerfordt's syndrome. On the basis of our experience, we suggest that physicians consider the possibility of Heerfordt's syndrome in cases of radiculopathy with unknown cause.
authors.affiliation: Department of Neurology, Fukuoka University Faculty of Medicine.
authors.forename: Kousuke
authors.initials: K
authors.lastname: Fukuhara
authors.forename: Aika
authors.initials: A
authors.lastname: Fukuhara
authors.forename: Jun
authors.initials: J
authors.lastname: Tsugawa
authors.forename: Shinji
authors.initials: S
authors.lastname: Oma
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Tsuboi
mesh_terms: D000328:Adult; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000188:drug therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D011843:Radiculopathy / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D012507:Sarcoidosis / Q000175:diagnosis / Q000188:drug therapy; D016896:Treatment Outcome; D014608:Uveoparotid Fever / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D011239:Prednisolone