title: Effect of menopause on cardiovascular disease and its risk factors: a 9-year follow-up study.
abstract: OBJECTIVE
  To explore the cardiovascular risk attributable to menopausal status in a 9-year follow-up, population-based study.
  
  
  METHODS
  All middle-aged women who met our eligibility criteria were selected from the Tehran Lipid and Glucose Study cohort. Data were collected by face-to-face interviews, physical examination and biochemical assessments at 3-year intervals. The World Health Organization classification was used to define menopausal status. Cardiovascular events that occurred in the cohort were investigated by a panel of medical specialists.
  
  
  RESULTS
  Based on menopausal status, there were no significant differences in cardiovascular disease after adjustment for age, body mass index and other confounders; however, significant relationships between serum concentrations of low density cholesterol and total cholesterol and menopausal status were observed.
  
  
  CONCLUSIONS
  Menopause, independent of other cardiovascular disease risk factors, incurred cardiometabolic risk.
authors.affiliation: * Reproductive Endocrinology Research Center.
authors.forename: F
authors.initials: F
authors.lastname: Ramezani Tehrani
authors.forename: S
authors.initials: S
authors.lastname: Behboudi-Gandevani
authors.forename: A
authors.initials: A
authors.lastname: Ghanbarian
authors.forename: F
authors.initials: F
authors.lastname: Azizi
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008593:Menopause; D012307:Risk Factors; D011795:Surveys and Questionnaires
chemical_list: D008078:Cholesterol, LDL; D002784:Cholesterol