title: Active pulmonary tuberculosis and latent tuberculosis infection among homeless people in Seoul, South Korea: a cross-sectional study.
abstract: BACKGROUND
  The aim of this study was to determine the prevalence rate of latent TB infection (LTBI) and active TB among homeless in Seoul metropolitan city, South Korea, and to compare the TB burden among homeless people with that of a control group.
  
  
  METHODS
  The homeless participants were recruited from five sites between October 30, 2009 and April 12, 2010. LTBI was diagnosed through the QuantiFERON(R) TB Gold In-Tube(QFT-GIT) assay and a tuberculin skin test(TST) and, and active PTB was diagnosed based on chest radiography.
  
  
  RESULTS
  Among 313 participants, the prevalence of LTBI was 75.9% (95% CI, 71.1-80.8%) and 79.8% (95% CI, 74.9-84.7%) based on a QFT-GIT assay and the TST, respectively, and that of active PTB was 5.8% (95% CI, 3.2-8.3%). The prevalence of LTBI among homeless participants was about five times higher than controls. Also, the age-specific prevalence rate ratio of active PTB was as high as 24.86.
  
  
  CONCLUSIONS
  The prevalence rate of LTBI as well as active PTB among homeless people was much higher than that of the general population in South Korea. Thus, adequate strategies to reduce the TB burden among homeless people are needed.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
authors.forename: Chang-Hoon
authors.initials: CH
authors.lastname: Lee
authors.forename: Yun-Jeong
authors.initials: YJ
authors.lastname: Jeong
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Heo
authors.forename: Jong Sun
authors.initials: JS
authors.lastname: Park
authors.forename: Ji Sun
authors.initials: JS
authors.lastname: Lee
authors.forename: Byoung Jun
authors.initials: BJ
authors.lastname: Lee
authors.forename: Young Sik
authors.initials: YS
authors.lastname: Park
authors.forename: Eun Hee
authors.initials: EH
authors.lastname: Song
authors.forename: Yun Jung
authors.initials: YJ
authors.lastname: Yang
authors.forename: Young Soo
authors.initials: YS
authors.lastname: Cho
authors.forename: En-hi
authors.initials: EH
authors.lastname: Cho
authors.forename: Kyoung-in
authors.initials: KI
authors.lastname: Na
authors.forename: Eun-Jeong
authors.initials: EJ
authors.lastname: Oh
authors.forename: Jin-beom
authors.initials: JB
authors.lastname: Lee
authors.forename: Soo-Yeon
authors.initials: SY
authors.lastname: Oh
authors.forename: HeeJin
authors.initials: H
authors.lastname: Kim
authors.forename: Chang Min
authors.initials: CM
authors.lastname: Park
authors.forename: Jae-Joon
authors.initials: JJ
authors.lastname: Yim
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017281:Cost of Illness; D003430:Cross-Sectional Studies; D005260:Female; D006703:Ill-Housed Persons / Q000706:statistics & numerical data*; D006801:Humans; D055985:Latent Tuberculosis / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000453:epidemiology*; D014505:Urban Population
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