title: Asymmetric synthesis of (+)- and (-)-pauciflorol F: confirmation of absolute stereochemistry.
abstract: An efficient, formal enantioselective synthesis of (+)- and (-)-pauciflorol F has been achieved using a recently introduced oxazolidinone controlled torquoselective Nazarov reaction. The absolute stereochemistry of pauciflorol F and its biosynthetic precursors has been unambiguously confirmed using X-ray crystallography.
authors.affiliation: Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Vic 3052, Australia.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Kerr
authors.forename: Michael
authors.initials: M
authors.lastname: Miletic
authors.forename: Narasimhulu
authors.initials: N
authors.lastname: Manchala
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: White
authors.forename: Bernard L
authors.initials: BL
authors.lastname: Flynn
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D015394:Molecular Structure; D013237:Stereoisomerism; D013267:Stilbenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D013267:Stilbenes; C487911:pauciflorol F