title: Drug delivery approaches for ovarian cancer therapy.
abstract: Tumor-specific drug delivery represents a challenging issue that restricts the clinical applications of many advanced anticancer therapeutics. Ovarian cancer exhibits a quite specific pattern of dissemination: it spreads primarily within the peritoneal cavity, providing a possibility of locoregional, intraperitoneal drug administration. Considering this unique aspect of ovarian cancer biology, this chapter provides a short review of most promising approaches for therapeutic delivery of genetic drugs.
authors.affiliation: Laboratory of Oncoendocrinology, NN Petrov Institute of Oncology, St. Petersburg, Russia.
authors.forename: Anastasia
authors.initials: A
authors.lastname: Malek
mesh_terms: D004333:Drug Administration Routes; D016503:Drug Delivery Systems / Q000379:methods*; D005260:Female; D015316:Genetic Therapy; D006801:Humans; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000473:pathology; D010529:Peritoneal Cavity