title: Epidemiology of malignant pleural mesothelioma in the province of Sassari (Sardinia, Italy). A population-based report.
abstract: The aim of this population-based study was to analyze and describe the epidemiological characteristics and trends of malignant pleural mesothelioma in the province of Sassari (Sardinia, Italy), in the period 1992-2010. Data were obtained from the local tumor registry which makes part of a wider registry web, coordinated today by the Italian Association for Tumor Registries. The overall number of malignant pleural mesothelioma cases registered was 70. The male-to-female ratio was 4:1 and the mean age 65.1 years for males and 63.4 years for females. The standardized incidence rates were 1.2/100,000 and 0.3/100,000 and the standardized mortality rates 0.6/100,000 and 0.2/100,000 for males and females respectively. A trend to increase in incidence in recent years was evidenced. This trend seems to follow the general national tendency and it depends on a large diffusion of asbestos usage in the past, delayed legislative interventions and probably a cleaning strategy of residual contamination fonts to intensify. The relative 5 years survival was low, suggesting the necessity to further intensify research and cure methods for the treatment of this extremely aggressive disease.
  
  
  BACKGROUND
  Asbestos exposure, Mesothelioma, Pleura, Sassari.
authors.forename: Mario
authors.initials: M
authors.lastname: Budroni
authors.forename: Antonio
authors.initials: A
authors.lastname: Cossu
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Paliogiannis
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Palmieri
authors.forename: Federico
authors.initials: F
authors.lastname: Attene
authors.forename: Rosaria
authors.initials: R
authors.lastname: Cesaraccio
authors.forename: Francesco
authors.initials: F
authors.lastname: Tanda
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001194:Asbestos / Q000009:adverse effects*; D002273:Carcinogens; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007558:Italy / Q000453:epidemiology; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000209:etiology* / Q000401:mortality; D008297:Male; D008654:Mesothelioma / Q000453:epidemiology* / Q000209:etiology* / Q000401:mortality; D000086002:Mesothelioma, Malignant; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000453:epidemiology* / Q000209:etiology* / Q000401:mortality; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D015996:Survival Rate
chemical_list: D002273:Carcinogens; D001194:Asbestos