title: Chemical modulation of bioactive compounds via oligopeptide or amino acid conjugation.
abstract: Conjugation of an oligopeptide or an amino acid to bioactive compounds is one of the simplest chemical modifications to modulate the biological functions of the compounds. Recently, numerous methods have been proposed for the modification of their properties, including the alteration of their chemical and physical properties, and of their original bioactivities. We review the current knowledge of the adaptability of oligopeptide or amino acid conjugation for modulating the biological activities of biomolecules.
authors.affiliation: School of Chemical and Biological Engineering, Seoul National University, Seoul, 151-744, Republic of Korea; Department of Chemical Engineering, Hanyang University, Ansan, 426-791, Republic of Korea.
authors.forename: Seon-Yeong
authors.initials: SY
authors.lastname: Kwak
authors.forename: Jin-Kyoung
authors.initials: JK
authors.lastname: Yang
authors.forename: Jong-Ho
authors.initials: JH
authors.lastname: Kim
authors.forename: Yoon-Sik
authors.initials: YS
authors.lastname: Lee
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D009842:Oligopeptides
chemical_list: D000596:Amino Acids; D009842:Oligopeptides
keywords: amino acid conjugation; chemical modulation; oligopeptide conjugation