title: Cognitive behavioural therapy for obsessive-compulsive disorder with comorbid schizophrenia: a case report with repetitive measurements.
abstract: BACKGROUND
  Obsessive-compulsive disorder (OCD) has been observed in a substantial proportion of patients with schizophrenia. Although cognitive-behavioural therapy (CBT) is well documented for OCD, few case studies are available regarding CBT for comorbid OCD in schizophrenia.
  
  
  OBJECTIVE
  The study aims to present a case study to augment the limited knowledge concerning CBT treatment for OCD in patients with schizophrenia.
  
  
  METHODS
  The research adopted a case study approach, with a baseline condition and repeated assessments during the 3-week treatment and 6-month follow-up period.
  
  
  RESULTS
  The treatment was successful and the patient achieved clinical significant change in OCD symptoms. The patient had a reduction on the Y-BOCS from 24 to 5 (79%) and from 38 to 10 (73%) on the OCI-R from before treatment to 6 months follow-up. He did not fulfil the criteria for an OCD diagnosis at the end of the 3-week treatment period, or the follow-up at 3- and 6 months.
  
  
  CONCLUSIONS
  The results strengthen the impressions given by previous case studies suggesting that CBT may be a promising treatment for OCD in patients with schizophrenia.
authors.affiliation: St. Olav's University Hospital, and Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Kristen
authors.initials: K
authors.lastname: Hagen
authors.affiliation: Norwegian University of Science and Technology, and St Olav's University Hospital, Trondheim, Norway.
authors.forename: Stian
authors.initials: S
authors.lastname: Solem
authors.affiliation: University Hospital, Bergen, and Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Bjarne
authors.initials: B
authors.lastname: Hansen
mesh_terms: D000328:Adult; D003024:Clozapine / Q000627:therapeutic use; D003131:Combined Modality Therapy; D015897:Comorbidity; D005500:Follow-Up Studies; D006801:Humans; D007171:Implosive Therapy / Q000379:methods; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000523:psychology* / Q000628:therapy*; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011594:Psychometrics; D013811:Psychotherapeutic Processes; D011788:Quality of Life; D012563:Schizophrenia, Paranoid / Q000175:diagnosis / Q000523:psychology* / Q000628:therapy*; D012648:Self Care / Q000523:psychology
chemical_list: D003024:Clozapine