title: The relationship between Anti-Müllerian hormone and other reproductive parameters in normal women and in women with polycystic ovary syndrome.
abstract: OBJECTIVE
  To correlate Anti-Müllerian hormone (AMH) levels with years since menarche as well as to investigate the AMH relationship with ovarian morphology and levels of androgens in healthy normo- ovulatory women and in women with polycystic ovary syndrome (PCOS).
  
  
  METHODS
  Prospective clinical study.
  
  
  METHODS
  University Hospital of Alexandroupolis, Lito Maternity Hospital.
  
  
  METHODS
  Forty two healthy normo-ovulatory women and sixty one women with PCOS, recruited on the basis of the classic PCOS criteria (Rotterdam consensus meeting definition of PCOS (ESHRE/ASRM, 2004).
  
  
  METHODS
  Fasting blood was obtained from all subjects in the early follicular phase (days 5-6) after spontaneous or induced menses (in PCOS), and transvaginal ultrasound examination was performed.
  
  
  METHODS
  Assessment of values for follicular stimulating hormone (FSH), testosterone (T), AMH, as well as assessments of years since menarche and ovarian volume.
  
  
  RESULTS
  AMH had a statistically significant positive correlation with the ovarian volume (r =0,623, r =0,579 P<0.01) and negative correlation with years since menarche (r =-0,766, r =-0,796 (P<0.01). In women with PCOS, AMH and years since menarche had a significant correlation with testosterone (r =0,477, r = -0,527, P<0.01) CONCLUSIONS: This study underlines the relation between AMH and years since menarche as well as the AMH differences in relation with certain clinical or endocrine characteristics between normal and PCOS women.
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece. nikoleta_koutlaki@yahoo.gr
authors.forename: N
authors.initials: N
authors.lastname: Koutlaki
authors.forename: M
authors.initials: M
authors.lastname: Dimitraki
authors.forename: S
authors.initials: S
authors.lastname: Zervoudis
authors.forename: C
authors.initials: C
authors.lastname: Poiana
authors.forename: A
authors.initials: A
authors.lastname: Psillaki
authors.forename: I
authors.initials: I
authors.lastname: Nikas
authors.forename: A
authors.initials: A
authors.lastname: Liberis
authors.forename: C
authors.initials: C
authors.lastname: Badiu
authors.forename: V
authors.initials: V
authors.lastname: Liberis
mesh_terms: D054304:Anti-Mullerian Hormone / Q000097:blood*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D016014:Linear Models; D011085:Polycystic Ovary Syndrome / Q000097:blood*; D011446:Prospective Studies; D013739:Testosterone / Q000097:blood
chemical_list: D013739:Testosterone; D054304:Anti-Mullerian Hormone; D005640:Follicle Stimulating Hormone
keywords: Anti-Müllerian hormone; PCOS; menarche; ovarian volume; testosterone
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