title: A self antigen reopens the games in pancreatic cancer.
abstract: We have recently demonstrated that the administration of a plasmid coding for α-enolase can elicit robust immune responses in genetically engineered mice that spontaneously develop pancreatic cancer, resulting in a significant improvement of their survival. This approach provides a springboard for the elaboration of new forms of immunotherapy for pancreatic cancer.
authors.affiliation: Center for Experimental Research and Medical Studies (CERMS); Città della Salute e della Scienza di Torino; University of Torino; Torino, Italy ; Department of Molecular Biotechnology and Health Sciences; University of Torino; Torino, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Cappello
authors.forename: Francesco
authors.initials: F
authors.lastname: Novelli
keywords: DNA vaccination; cancer immunotherapy; mouse models; pancreatic cancer; α-enolase
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