title: PXR-ALAS1: a key regulatory pathway in liver toxicity induced by isoniazid-rifampicin antituberculosis treatment.
authors.affiliation: Université Versailles-Saint-Quentin-en-Yvelines, Guyancourt, France; Inserm U773, université Paris-Diderot, centre de recherche biomédicale Bichat-Beaujon, site Bichat, Paris, France.
authors.forename: Said
authors.initials: S
authors.lastname: Lyoumi
authors.forename: Thibaud
authors.initials: T
authors.lastname: Lefebvre
authors.forename: Zoubida
authors.initials: Z
authors.lastname: Karim
authors.forename: Laurent
authors.initials: L
authors.lastname: Gouya
authors.forename: Hervé
authors.initials: H
authors.lastname: Puy
mesh_terms: D000818:Animals; D000995:Antitubercular Agents / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects*; D008297:Male; D011987:Receptors, Steroid / Q000187:drug effects*; D012293:Rifampin / Q000009:adverse effects*
chemical_list: D000995:Antitubercular Agents; D011987:Receptors, Steroid; D007538:Isoniazid; D012293:Rifampin