title: [Double esophageal carcinosarcomas showing rapid growth of a new polypoid tumor after sloughing of another polypoid tumor].
abstract: A 55-year-old man presented at our hospital with a large polypoid esophageal tumor. Initial upper gastrointestinal endoscopy revealed that this tumor had sloughed off to be replaced with ulceration in the thoracic esophagus. However, after the tumor at the thoracic esophagus sloughed off, a semi-circular, superficial, flat squamous cell carcinoma was observed adjacent to the ulceration. In addition, a separate carcinosarcoma, 2cm in diameter, was found at the esophagogastric junction. Approximately one month later, endoscopic re-examination revealed a new polypoid tumor approximately 4cm in diameter that was growing rapidly in the center of the superficial thoracic esophageal carcinoma lesion. Standard subtotal esophagectomy was performed. Histopathological examination revealed that both lesions were esophageal carcinosarcomas. This is a rare case of double esophageal carcinosarcoma associated with rapid polypoid tumor growth from a superficial squamous cell carcinoma lesion.
authors.affiliation: Department of Gastroenterology, Kobe City Medical Center West Hospital, Japan. yamashita@kobe-nishishimin-hospi.jp
authors.forename: Yukimasa
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Masashi
authors.initials: M
authors.lastname: Fukushima
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Sumitomo
authors.forename: Yongi
authors.initials: Y
authors.lastname: Son
authors.forename: Masayuki
authors.initials: M
authors.lastname: Maruo
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Itai
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ono
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Kimura
authors.forename: Eiji
authors.initials: E
authors.lastname: Ikeda
authors.forename: Mariko
authors.initials: M
authors.lastname: Takada
authors.forename: Sakae
authors.initials: S
authors.lastname: Mikami
authors.forename: Takayuki
authors.initials: T
authors.lastname: Nishigami
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002296:Carcinosarcoma / Q000473:pathology*; D016099:Endoscopy, Gastrointestinal; D004938:Esophageal Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology