title: The relationship between traits optimism and anxiety and health-related quality of life in patients hospitalized for chronic diseases: data from the SATISQOL study.
abstract: BACKGROUND
  The impact of psychological factors is often taken into account in the evaluation of quality of life. However, the effect of optimism and trait anxiety remains controversial and they are rarely studied simultaneously. We aimed to study the effect of this factor on health-related quality of life (HRQOL) of patients after a hospitalization in relation with their chronic disease.
  
  
  METHODS
  Using cross-sectional data from the SATISQOL cohort, we conducted a multicentric study, including patients hospitalized for an intervention in connection with their chronic disease. Six months after hospitalization, patients completed a generic HRQOL questionnaire (SF-36), and the STAI and LOT-R questionnaires to evaluate optimism and trait anxiety. We studied the effect of each trait on HRQOL separately, and simultaneously, taking account of their interaction in 3 models, using an ANOVA.
  
  
  RESULTS
  In this study, 1529 patients were included in three participating hospitals and there existed wide diversity in the chronic diseases in our population. The HRQOL score increased for all dimensions of SF36 between 15,8 and 44,5 when the level of anxiety decreased (p < 0.0001) for the model 1, assessing the effect of anxiety on HRQOL and increased for all dimensions of SF36 between 3.1 and 12.7 with increasing level of optimism (< 0.0001) in the model 2 assessing the effect of optimism on HRQOL. In the model 3, assessing the effect of both anxiety and optimism on HRQOL, and their interaction, the HRQOL score for all dimensions of the SF36 increased when the level of anxiety decreased (p < 0.0001). It increased with increasing level of optimism (p < 0.006) in the model for all dimensions of SF36 except the Role Physical dimension. In this model, interaction between anxiety and optimism was significant for the Social Functioning dimension (p = 0.0021).
  
  
  CONCLUSIONS
  Optimism and trait anxiety appeared to be significantly correlated with HRQOL. Furthermore, an interaction existed between the trait anxiety and optimism for some dimensions of SF36. Contrary to optimism, it seems essential to evaluate trait anxiety in future studies about HRQOL, since it could represent a confounding factor.
authors.affiliation: University of Franche-Comté, UPRES EA 3181, Besançon, France. sabrinakepka@yahoo.fr
authors.forename: Sabrina
authors.initials: S
authors.lastname: Kepka
authors.forename: Cédric
authors.initials: C
authors.lastname: Baumann
authors.forename: Amélie
authors.initials: A
authors.lastname: Anota
authors.forename: Gaelle
authors.initials: G
authors.lastname: Buron
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Spitz
authors.forename: Pascal
authors.initials: P
authors.lastname: Auquier
authors.forename: Francis
authors.initials: F
authors.lastname: Guillemin
authors.forename: Mariette
authors.initials: M
authors.lastname: Mercier
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001007:Anxiety / Q000175:diagnosis / Q000523:psychology*; D002908:Chronic Disease / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy; D015331:Cohort Studies; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011594:Psychometrics; D019984:Quality Indicators, Health Care; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires
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