title: Parental permissions: H19 and keeping the stem cell progeny under control.
abstract: H19 is shown by Venkatraman et al. (2013), using maternal-allele-specific deletion of the differentially methylated region, to maintain hematopoietic stem cell repopulating ability through a miR-675-Igf1r signaling circuit. This work establishes function in somatic stem cells for another member of a putative imprinted gene network that may influence organismal growth.
authors.affiliation: Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX 77030, USA. goodell@bcm.edu
authors.forename: Margaret A
authors.initials: MA
authors.lastname: Goodell
mesh_terms: D053687:Adult Stem Cells / Q000166:cytology* / Q000502:physiology*; D000818:Animals; D018392:Genomic Imprinting; D007335:Insulin-Like Growth Factor II / Q000235:genetics* / Q000378:metabolism*; D062085:RNA, Long Noncoding / Q000235:genetics* / Q000378:metabolism*
chemical_list: D062085:RNA, Long Noncoding; D007335:Insulin-Like Growth Factor II