title: Catatonic schizophrenia: therapeutic challenges and potentially a new role for electroconvulsive therapy?
abstract: A 36-year-old man with known schizophrenia, presented with increasingly bizarre behaviour. The development of catatonia and subsequent neuroleptic malignant syndrome in itself posed numerous therapeutic challenges. However, following resolution of neuroleptic malignant syndrome, the reintroduction of antipsychotics was not tolerated. This case report proposes a novel use for electroconvulsive therapy as a treatment of mental state, following resolution of neuroleptic malignant syndrome, to facilitate successful reintroduction of antipsychotics.
authors.affiliation: St Brigid's Hospital, Co Galway, Ireland. philbind@tcd.ie
authors.forename: Deirdre
authors.initials: D
authors.lastname: Philbin
authors.forename: D
authors.initials: D
authors.lastname: Mulryan
authors.forename: M
authors.initials: M
authors.lastname: O'Grady
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D004565:Electroconvulsive Therapy; D006801:Humans; D008297:Male; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology / Q000628:therapy*; D012560:Schizophrenia, Catatonic / Q000188:drug therapy*
chemical_list: D014150:Antipsychotic Agents
references.citation: J Natl Med Assoc. 1992 Sep;84(9):800-2
references.pmid: 1404479
references.citation: Br J Anaesth. 2000 Jul;85(1):129-35
references.pmid: 10928001
references.citation: Aust N Z J Psychiatry. 1999 Oct;33(5):650-9
references.pmid: 10544988
references.citation: Encephale. 2010 Apr;36(2):105-10
references.pmid: 20434626
references.citation: J Clin Psychiatry. 1998 May;59(5):254-5
references.pmid: 9632037
references.citation: Minerva Psichiatr. 1994 Dec;35(4):199-219
references.pmid: 7861943
references.citation: Biol Psychiatry. 1998 Sep 15;44(6):499-507
references.pmid: 9777183
references.citation: Drugs. 2004;64(15):1715-36
references.pmid: 15257633
references.citation: Int Clin Psychopharmacol. 2004 Nov;19(6):351-3
references.pmid: 15486522
references.citation: Parkinsonism Relat Disord. 2003 Apr;9 Suppl 1:S3-9
references.pmid: 12735909
references.citation: Am J Psychiatry. 1999 Feb;156(2):169-80
references.pmid: 9989551