title: Enhanced photothermal effect of plasmonic nanoparticles coated with reduced graphene oxide.
abstract: We report plasmonic gold nanoshells and nanorods coated with reduced graphene oxide that produce an enhanced photothermal effect when stimulated by near-infrared (NIR) light. Electrostatic interactions between nanosized graphene oxide and gold nanoparticles followed by in situ chemical reduction generated reduced graphene oxide-coated nanoparticles; the coating was demonstrated using Raman and HR-TEM. Reduced graphene oxide-coated gold nanoparticles showed enhanced photothermal effect compared to noncoated or nonreduced graphene oxide-coated gold nanoparticles. Reduced graphene oxide-coated gold nanoparticles killed cells more rapidly than did noncoated or nonreduced graphene oxide-coated gold nanoparticles.
authors.affiliation: Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Children's Hospital Boston, Harvard Medical School , 300 Longwood Avenue, Boston, Massachusetts 02115, United States.
authors.forename: Dong-Kwon
authors.initials: DK
authors.lastname: Lim
authors.forename: Aoune
authors.initials: A
authors.lastname: Barhoumi
authors.forename: Ryan G
authors.initials: RG
authors.lastname: Wylie
authors.forename: Gally
authors.initials: G
authors.lastname: Reznor
authors.forename: Robert S
authors.initials: RS
authors.lastname: Langer
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Kohane
mesh_terms: D002470:Cell Survival; D006046:Gold / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D061307:Human Umbilical Vein Endothelial Cells; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D057145:Nanoshells / Q000737:chemistry; D036103:Nanotechnology; D043942:Nanotubes / Q000737:chemistry; D055095:Optics and Photonics; D010087:Oxides / Q000737:chemistry*; D020349:Surface Plasmon Resonance
chemical_list: D010087:Oxides; D006046:Gold; D006108:Graphite