title: Patients with penile cancer and the risk of (pre)malignant cervical lesions in female partners: a retrospective cohort analysis.
abstract: OBJECTIVE
  To determine if female partners of patients with penile cancer have more cervical lesions and neoplasia than would be expected from population-based data.
  
  
  METHODS
  We included all consecutive patients with primary penile carcinoma in the period 2004-2010. Results of Dutch cervical cancer screening were used to consider (pre)malignant cervical lesions in female partners of patients with penile cancer.
  
  
  RESULTS
  In all, 206 women were included. Gynaecological information was available in 195 women: Papanicolaou test (PAP) smears were normal were in 129 partners, 10 smears were abnormal (5.1%, 95% confidence interval 2.5-9.2). PAP2 was found in five, PAP3a in two, PAP3b in two women and PAP4 in one woman. Colposcopy in two women with PAP3b showed cervical intraepithelial neoplasia grade 3 in both. This prevalence was not different from baseline results in the general Dutch population.
  
  
  CONCLUSIONS
  Female partners of patients with penile cancer did not show more premalignant cervical lesions than in the general population.
authors.affiliation: Department of Urology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
authors.forename: Roderick E
authors.initials: RE
authors.lastname: de Bruijn
authors.forename: Danielle A M
authors.initials: DA
authors.lastname: Heideman
authors.forename: Gemma G
authors.initials: GG
authors.lastname: Kenter
authors.forename: Marc
authors.initials: M
authors.lastname: van Beurden
authors.forename: Harm
authors.initials: H
authors.lastname: van Tinteren
authors.forename: Simon
authors.initials: S
authors.lastname: Horenblas
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms; D011230:Precancerous Conditions / Q000453:epidemiology* / Q000473:pathology*; D012189:Retrospective Studies; D012307:Risk Factors; D012747:Sexual Partners; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000473:pathology*
keywords: human papilloma virus; penile neoplasms; uterine cervical neoplasms