title: The diagnosis and management of brain arteriovenous malformations.
abstract: Although uncommon in the general population, cerebral arteriovenous malformations (AVMs) can pose a significant health risk if a rupture occurs. Advances in noninvasive imaging have led to an increase in the identification of unruptured AVMs, presenting new challenges in management, given their poorly understood natural history. Over the past decade, there have been significant developments in the management and treatment of intracranial AVMs. This article discusses the pathophysiology, natural history, clinical presentations, and current treatment options, including multimodal approaches, for these vascular malformations.
authors.affiliation: Neuroradiology Division, Department of Radiology, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9178, USA.
authors.forename: Roberta L
authors.initials: RL
authors.lastname: Novakovic
authors.forename: Marc A
authors.initials: MA
authors.lastname: Lazzaro
authors.forename: Alicia C
authors.initials: AC
authors.lastname: Castonguay
authors.forename: Osama O
authors.initials: OO
authors.lastname: Zaidat
mesh_terms: D001921:Brain / Q000473:pathology; D002533:Cerebral Angiography; D057510:Endovascular Procedures; D006470:Hemorrhage / Q000209:etiology / Q000628:therapy; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D012640:Seizures / Q000209:etiology / Q000628:therapy
keywords: AVM treatment; Arteriovenous malformations; Embolization; Radiosurgery; Surgical resection