title: A photoelectrochemical immunosensor for tris(2,3-dibromopropyl) isocyanurate detection with a multiple hybrid CdTe/Au-TiO2 nanotube arrays.
abstract: In this paper, tris(2,3-dibromopropyl) isocyanurate (TBC) is for the first time as far as we know determined by ultrasensitive photoelectrochemical (PEC) immunoassay using an antibody-modified ternary hybrid CdTe/Au-TiO2 nanotube arrays (NTAs) photoelectrode, developed by the pulse electrodeposition technique. The as-prepared hybrid shows enhanced photon absorption and photocurrent response, which subsequently increased the photoelectrical conversion efficiency in the visible region. TBC-antibody (Ab) was developed in rabbits as a result of immunization with the BSA-TBC conjugate and covalently cross-linked onto the CdTe/Au-TiO2 NTAs. Since the photocurrent is highly dependent on the TiO2 surface properties, the specific interaction between TBC and the antibody results in a sensitive change in the photocurrent, which displayed a linear range of 5.0 × 10(-11) to 5.0 × 10(-5) M and a low detection limit of 5.0 × 10(-11) M for TBC determination. This proposed strategy highlights the application of TiO2 nanotube in visible-light-activated photoelectrochemical biosensing, which could largely reduce the destructive effect of UV light on biomolecules.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, IN 410082, China. qycai0001@hnu.edu.cn.
authors.forename: Hui
authors.initials: H
authors.lastname: Feng
authors.forename: Liping
authors.initials: L
authors.lastname: Zhou
authors.forename: Jiezhen
authors.initials: J
authors.lastname: Li
authors.forename: ThanhThuy
authors.initials: T
authors.lastname: Tran T
authors.forename: Niya
authors.initials: N
authors.lastname: Wang
authors.forename: Lijuan
authors.initials: L
authors.lastname: Yuan
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Yan
authors.forename: Qingyun
authors.initials: Q
authors.lastname: Cai
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000379:methods*; D019187:Cadmium Compounds / Q000737:chemistry; D003722:Dental Alloys / Q000737:chemistry; D055664:Electrochemical Techniques / Q000379:methods*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D007118:Immunoassay / Q000379:methods; D043942:Nanotubes / Q000737:chemistry*; D010755:Organophosphates / Q000737:chemistry; D055668:Photochemical Processes; D011817:Rabbits; D013691:Tellurium / Q000737:chemistry; D014227:Triazines / Q000737:chemistry
chemical_list: D019187:Cadmium Compounds; D003722:Dental Alloys; D010755:Organophosphates; D014227:Triazines; C416206:gold-titanium alloy; C509473:isocyanuric acid; C012085:tris(2,3-dibromopropyl)phosphate; D013691:Tellurium; C028337:cadmium telluride