title: Is daytime blood pressure adequate in cardiovascular risk assessment in patients with coronary atherosclerosis?
abstract: OBJECTIVE
  The goal of our study was to estimate the impact of abnormal night-time blood pressure (BP) on cardiovascular (CV) mortality in hypertensive patients with significant atherosclerosis established in coronary angiography.
  
  
  METHODS
  We enrolled 891 patients, 63.7 ± 9.4 years of age. They were divided into patients with normal daytime BP values, and patients with abnormal daytime BP values. During a follow-up period of 4.7 years in total, all-cause mortality and both CV and non-CV mortality were assessed.
  
  
  RESULTS
  In the group with normal daytime BP, a clinic BP value ≥ 140/90 mmHg was observed in 25.7% (n = 161) of patients, and a night-time BP value ≥ 120/70 mmHg was observed in 37.8% (n = 236) of patients. In the group of patients with normal daytime BP in comparison with those with abnormal daytime BP, there was lower CV mortality (5.6% vs 9.8%, p < 0.02). Abnormal daytime BP was associated with a hazard ratio of CV mortality of 1.80 (95% CI 1.08-3.00, p < 0.02), and abnormal night-time BP with a hazard ratio of 1.63 (95% CI 1.03-2.66, p < 0.04).
  
  
  CONCLUSIONS
  Assessment of both daytime and night-time BP is essential and superior over clinic BP in CV risk evaluation in patients with coronary artery disease confirmed in coronary angiography.
authors.affiliation: I Department of Cardiology, Medical University of Gdansk , Debinki 7, 80-211 Gdansk , Poland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Sobiczewski
authors.forename: Marcin
authors.initials: M
authors.lastname: Wirtwein
authors.forename: Marcin
authors.initials: M
authors.lastname: Gruchala
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination; D018660:Blood Pressure Monitoring, Ambulatory; D002940:Circadian Rhythm / Q000502:physiology; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000401:mortality / Q000503:physiopathology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000401:mortality / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors; D015996:Survival Rate