title: Feasibility of newly developed endoscopic ultrasound with zone sonography technology for diagnosis of pancreatic diseases.
abstract: OBJECTIVE
  To confirm the feasibility of using newly developed endoscopic ultrasound (EUS) with Zone sonography™ technology (ZST; Fujifilm Corp.).
  
  
  METHODS
  Seventy-five patients with pancreatic disorders were enrolled: 45 with intraductal papillary mucinous neoplasm; 15 with ductal carcinoma; five with neuroendocrine tumors; three with serous cystic neoplasms; and seven with simple cysts. The endoscopes used were EG-530UR2 and EG-530UT2 (Fujifilm Corp.). Two items were evaluated: visualization depth among four frequencies and image quality after automatic adjustment of sound speed (AASS), assessed using a 5-scale Likert scale by two endosonographers blinded to disease status. Because sound speed could be manually controlled, besides AASS, image quality at sound speeds of 1,440 and 1,600 m/sec were also assessed.
  
  
  RESULTS
  In all cases, sufficient images were obtained in the range of 3 cm from the EUS probe. Judgments of image quality before AASS were 3.49±0.50, 3.65±0.48, respectively. After AASS, A and B scored 4.36±0.48 and 4.40±0.49 (p<0.0001). There were significant differences in the data before and after AASS and plus 60 m/sec, but no significant difference between the datasets were seen after AASS and at sound speeds manually set for minus 100 m/sec.
  
  
  CONCLUSIONS
  EUS with ZST was shown to be feasible in this preliminary experiment. Further evaluation of this novel technology is necessary and awaited.
authors.affiliation: Department of Endoscopy, Nagoya University Hospital, Nagoya, Japan.
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Hirooka
authors.forename: Akihiro
authors.initials: A
authors.lastname: Itoh
authors.forename: Hiroki
authors.initials: H
authors.lastname: Kawashima
authors.forename: Eizaburo
authors.initials: E
authors.lastname: Ohno
authors.forename: Yuya
authors.initials: Y
authors.lastname: Itoh
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hiramatsu
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Sugimoto
authors.forename: Hajime
authors.initials: H
authors.lastname: Sumi
authors.forename: Daijiro
authors.initials: D
authors.lastname: Hayashi
authors.forename: Naoki
authors.initials: N
authors.lastname: Ohmiya
authors.forename: Ryoji
authors.initials: R
authors.lastname: Miyahara
authors.forename: Masanao
authors.initials: M
authors.lastname: Nakamura
authors.forename: Kohei
authors.initials: K
authors.lastname: Funasaka
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Ishigami
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Katano
authors.forename: Hidemi
authors.initials: H
authors.lastname: Goto
keywords: Automatic adjustment of sound speed; Endosonography; Enhanced attenuation; ZONE sonography technology
references.citation: World J Clin Oncol. 2011 May 10;2(5):217-24
references.pmid: 21611098
references.citation: J Gastroenterol Hepatol. 2011 Aug;26(8):1256-61
references.pmid: 21501226
references.citation: J Ultrasound Med. 2010 Nov;29(11):1581-8
references.pmid: 20966469
references.citation: J Gastroenterol Hepatol. 2009 Mar;24(3):384-90
references.pmid: 19032453
references.citation: J Gastroenterol Hepatol. 2004 Apr;19(4):454-9
references.pmid: 15012785
references.citation: Ultrason Imaging. 1987 Jul;9(3):180-94
references.pmid: 3445403
references.citation: Ultrasonics. 2006 Dec 22;44 Suppl 1:e43-6
references.pmid: 17056083
references.citation: J Gastroenterol Hepatol. 2003 Nov;18(11):1323-4
references.pmid: 14535994
references.citation: Gastrointest Endosc. 2003 Jun;57(7):931-6
references.pmid: 12776049
references.citation: J Gastroenterol Hepatol. 2009 Jan;24(1):90-6
references.pmid: 19196396
references.citation: J Gastroenterol Hepatol. 2003 Jul;18(7):828-35
references.pmid: 12795756
references.citation: Rofo. 1999 Dec;171(6):480-4
references.pmid: 10668514
references.citation: Clin Gastroenterol Hepatol. 2009 Nov;7(11 Suppl):S63-7
references.pmid: 19896102
references.citation: J Acoust Soc Am. 1993 Oct;94(4):1944-52
references.pmid: 8227740