title: Chronic hepatitis B virus infection in women is not associated with IVF/ICSI outcomes.
abstract: OBJECTIVE
  This study was to evaluate whether chronic HBV (Hepatitis B virus) infection in women is associated with poor performance following IVF/ICSI (in vitro fertilization/intracytoplasmic sperm injection) treatments.
  
  
  METHODS
  123 cycles with female chronic HBV infection were compared with 246 cycles with no-infected couples, matched for female age, D3 serum FSH (follicles stimulation hormone) levels, body mass index and assisted reproductive technology approach used (IVF or ICSI), in a ratio of 1:2.
  
  
  RESULTS
  The details in IVF/ICSI cycles, including the dosage of gonadotrophin used, the serum estradiol levels and the endometrial thickness on the day of hCG (human chorionic gonadotrophin) injection, the mean number of oocytes retrieved, and the embryology data, were similar among seropositive and seronegative women. And there was no significant differences in implantation rates and live birth rates between seropositive women group and matched control (30.52 versus 28.34% per transfer; 42.28 versus 40.65%).
  
  
  CONCLUSIONS
  The results indicated that women with chronic HBV infection is not associated with outcomes of IVF/ICSI treatments.
authors.affiliation: The Reproductive Medicine Center, The Second Affiliated Hospital of WenZhou Medical University, WenZhou, China, chenhua_222@163.com.
authors.forename: Hua
authors.initials: H
authors.lastname: Chen
authors.forename: Hong-Shan
authors.initials: HS
authors.lastname: Ge
authors.forename: Jie-Qiang
authors.initials: JQ
authors.lastname: Lv
authors.forename: Xin-Mei
authors.initials: XM
authors.lastname: Wu
authors.forename: Hai-Tao
authors.initials: HT
authors.lastname: Xi
authors.forename: Jian-Ying
authors.initials: JY
authors.lastname: Huang
authors.forename: Chun-Fang
authors.initials: CF
authors.lastname: Zhu
mesh_terms: D000328:Adult; D010064:Embryo Implantation; D005260:Female; D005307:Fertilization in Vitro; D019694:Hepatitis B, Chronic / Q000150:complications*; D006801:Humans; D007247:Infertility, Female / Q000150:complications / Q000628:therapy*; D011247:Pregnancy; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic; D016896:Treatment Outcome