title: A statistical method for characterizing the noise in nonlinearly reconstructed images from undersampled MR data: the POCS example.
abstract: The projection-onto-convex-sets (POCS) algorithm is a powerful tool for reconstructing high-resolution images from undersampled k-space data. It is a nonlinear iterative method that attempts to estimate values for missing data. The convergence of the algorithm and its other deterministic properties are well established, but relatively little is known about how noise in the source data influences noise in the final reconstructed image. In this paper, we present an experimental treatment of the statistical properties in POCS and investigate 12 stochastic models for its noise distribution beside its nonlinear point spread functions. Statistical results show that as the ratio of the missing k-space data increases, the noise distribution in POCS images is no longer Rayleigh as with conventional linear Fourier reconstruction. Instead, the probability density function for the noise is well approximated by a lognormal distribution. For small missing data ratios, however, the noise remains Rayleigh distributed. Preliminary results show that in the presence of noise, POCS images are often dominated by POCS-enhanced noise rather than POCS-induced artifacts. Implicit in this work is the presentation of a general statistical method that can be used to assess the noise properties in other nonlinear reconstruction algorithms.
authors.affiliation: Department of Radiology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA. Electronic address: MSabati@med.miami.edu.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Sabati
authors.forename: Haidong
authors.initials: H
authors.lastname: Peng
authors.forename: M Louis
authors.initials: ML
authors.lastname: Lauzon
authors.forename: Richard
authors.initials: R
authors.lastname: Frayne
mesh_terms: D000465:Algorithms; D016477:Artifacts; D001921:Brain / Q000473:pathology; D005583:Fourier Analysis; D064368:Healthy Volunteers; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D017711:Nonlinear Dynamics; D019047:Phantoms, Imaging; D011336:Probability
keywords: Noise; Nonlinear image reconstruction; Point spread function; Projection-onto-convex sets (POCS); Random distributions; Sparse sampling; Statistical methods; Undersampled acquisition; Zero-filling