title: Antipsychotic treatment resistance in schizophrenia associated with elevated glutamate levels but normal dopamine function.
authors.affiliation: Department of Psychosis Studies, Institute of Psychiatry, King's College London; Psychiatric Imaging, MRC Clinical Sciences Centre.
authors.forename: Arsime
authors.initials: A
authors.lastname: Demjaha
authors.affiliation: Department of Psychosis Studies, Institute of Psychiatry, King's College London; Psychiatric Imaging, MRC Clinical Sciences Centre. Electronic address: Alice.Egerton@kcl.ac.uk.
authors.forename: Alice
authors.initials: A
authors.lastname: Egerton
authors.affiliation: Department of Psychosis Studies, Institute of Psychiatry, King's College London.
authors.forename: Robin M
authors.initials: RM
authors.lastname: Murray
authors.affiliation: Department of Psychosis Studies, Institute of Psychiatry, King's College London.
authors.forename: Shitij
authors.initials: S
authors.lastname: Kapur
authors.affiliation: Department of Psychosis Studies, Institute of Psychiatry, King's College London; Psychiatric Imaging, MRC Clinical Sciences Centre.
authors.forename: Oliver D
authors.initials: OD
authors.lastname: Howes
authors.affiliation: Centre for Mental Health, Division of Brain Sciences, Imperial College London.
authors.forename: James M
authors.initials: JM
authors.lastname: Stone
authors.affiliation: Department of Psychosis Studies, Institute of Psychiatry, King's College London.
authors.forename: Philip K
authors.initials: PK
authors.lastname: McGuire
mesh_terms: D000704:Analysis of Variance; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives / Q000493:pharmacokinetics; D004298:Dopamine / Q000378:metabolism*; D005260:Female; D018698:Glutamic Acid / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D049268:Positron-Emission Tomography; D011522:Protons; D012559:Schizophrenia / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000378:metabolism*
chemical_list: D014150:Antipsychotic Agents; D011522:Protons; C043437:fluorodopa F 18; D001224:Aspartic Acid; D018698:Glutamic Acid; D004295:Dihydroxyphenylalanine; C000179:N-acetylaspartate; D004298:Dopamine