title: Epidemiology of oral-cavity and oropharyngeal carcinomas: controlling a tobacco epidemic while a human papillomavirus epidemic emerges.
abstract: Although tobacco prevalence is declining in most developed countries, less developed countries are still experiencing an increase in tobacco use. Thus the future burden of oral-cavity and oropharyngeal cancers in less developed countries is expected to be heavy. The incidence of human papillomavirus (HPV)-associated oropharyngeal cancer is dramatically increasing in the United States and other developed countries, although trends in less developed countries are not clear at present. HPV vaccine compliance in the United States is low, although it continues to increase each year. Increasing the HPV vaccination rate to control future HPV-associated cancer incidence remains a priority.
authors.affiliation: Division of Public Health, Department of Family & Preventive Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, 375 Chipeta Way, Suite A, Salt Lake City, UT 84108, USA. mia.hashibe@utah.edu
authors.forename: Mia
authors.initials: M
authors.lastname: Hashibe
authors.forename: Erich M
authors.initials: EM
authors.lastname: Sturgis
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D017281:Cost of Illness; D058872:Epidemics; D005260:Female; D014943:Global Health; D006801:Humans; D015994:Incidence; D008297:Male; D009062:Mouth Neoplasms / Q000453:epidemiology*; D009959:Oropharyngeal Neoplasms / Q000453:epidemiology*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000473:pathology*; D012307:Risk Factors; D014029:Tobacco Use Disorder / Q000150:complications / Q000453:epidemiology* / Q000517:prevention & control; D055815:Young Adult
keywords: HPV vaccine; Human papillomavirus; Oropharyngeal cancer; Tobacco