title: Bivalirudin for prevention of prosthetic valve thrombosis in heparin allergy.
abstract: A 68-year-old male was admitted for implantation of an implantable cardioverter defibrillator (ICD). He had a prosthetic mechanical valve for which he was receiving anticoagulation with warfarin, but had developed an allergy to heparin. Therefore, we decided to use bivalirudin for anticoagulation, which permitted him to undergo the procedure without complications.
authors.affiliation: Instituto Cardiovascular, Hospital Clínico San Carlos, C/Prof. Martín Lagos, s/n, Madrid, Spain.
authors.forename: Julián
authors.initials: J
authors.lastname: Palacios-Rubio
authors.forename: Leonel
authors.initials: L
authors.lastname: Cano
authors.forename: Isidre
authors.initials: I
authors.lastname: Vilacosta
authors.forename: David
authors.initials: D
authors.lastname: Vivas
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage; D002315:Cardiopulmonary Bypass; D017147:Defibrillators, Implantable; D004342:Drug Hypersensitivity / Q000209:etiology*; D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D006350:Heart Valve Prosthesis; D006493:Heparin / Q000009:adverse effects*; D006629:Hirudins / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008943:Mitral Valve; D010446:Peptide Fragments / Q000008:administration & dosage*; D019919:Prosthesis Implantation; D011994:Recombinant Proteins / Q000008:administration & dosage; D013927:Thrombosis / Q000517:prevention & control*; D014859:Warfarin / Q000008:administration & dosage
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006629:Hirudins; D010446:Peptide Fragments; D011994:Recombinant Proteins; D014859:Warfarin; D006493:Heparin; C074619:bivalirudin