title: Comparison of outcomes and survivorship between patients of different age groups following TKA.
abstract: A total of 6275 consecutive TKA patients were divided into three groups based on their age: <55, 55-70 and >70 years. There was a statistically significant difference in the change in WOMAC score (32 vs 31 vs 26, P<0.001) and Knee Society Score (78.9 vs 76.0 vs 69.0, P<0.001) favoring the younger populations. However, the revision rate was higher in the younger patients with a Kaplan-Meier survivorship at 5 years of 95.5%, 97.2% and 98.1% and at 10 years of 92.2%, 95.9% and 97.6%. Infection was the most frequent cause for failure in all groups although aseptic loosening and instability accounted for the increased revision rate in the younger patients. Younger patients may experience slightly better clinical outcomes following TKA but lower survivorship, when compared to older patient populations.
authors.affiliation: London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada.
authors.forename: Richard W
authors.initials: RW
authors.lastname: McCalden
authors.forename: Christopher E
authors.initials: CE
authors.lastname: Robert
authors.forename: James L
authors.initials: JL
authors.lastname: Howard
authors.forename: Douglas D
authors.initials: DD
authors.lastname: Naudie
authors.forename: James P
authors.initials: JP
authors.lastname: McAuley
authors.forename: Steven J
authors.initials: SJ
authors.lastname: MacDonald
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation / Q000401:mortality*; D005260:Female; D006801:Humans; D015994:Incidence; D053208:Kaplan-Meier Estimate; D007720:Knee Prosthesis / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery*; D016459:Prosthesis-Related Infections / Q000453:epidemiology; D015996:Survival Rate; D016896:Treatment Outcome
keywords: TKA; age-related; outcomes; survivorship