title: Current trends in the management of the complications of chronic otitis media with cholesteatoma.
abstract: OBJECTIVE
  Complications of cholesteatoma can be of a different nature from those of other otitis media. This review aims to undertake an analysis of current literature regarding management of the complications of cholesteatoma.
  
  
  RESULTS
  Despite a significant decline in the incidence of complications secondary to cholesteatoma in developed countries it is still a considerable problem in the developing countries. Among intratemporal complications, facial nerve paralysis and labrynthine fistula and among intracranial complications, meningitis, brain abscess and lateral sinus thrombosis are most common. In cases of facial nerve paralysis, decompression with complete disease eradication is considered to be the mainstay of treatment and usefulness of an epineural incision and the range of the decompression are still debatable. Labyrinthine fistula is commonly managed by a single staged matrix removal, followed by closure of the fistula. Partial labrynthectomy in difficult cases is gaining favor among surgeons today. Meningitis and brain abscesses are treated with antibiotics and steroid therapy followed by surgery when the patient is neurologically stable. In lateral sinus thrombosis, mastoidectomy and removal of infected tissue is the primary treatment. Sinus incision and thrombectomy does not seem to improve recanalization and anticoagulation is usually not necessary. Treatment of meningoencephalic herniations is based mainly on the diameter of the herniation.
  
  
  CONCLUSIONS
  There is considerable debate in the management of almost every complication of cholesteatoma. Multicentric studies to compare the efficacies of various treatment modalities are the need of the hour to come to definitive conclusions regarding the best treatment options.
authors.affiliation: Department of Otology, Neurotology & Skull Base Surgery, Gruppo Otologico, Piacenza-Rome, Italy. sampathcp@yahoo.co.in
authors.forename: Sampath C
authors.initials: SC
authors.lastname: Prasad
authors.forename: Seung-Ho
authors.initials: SH
authors.lastname: Shin
authors.forename: Alessandra
authors.initials: A
authors.lastname: Russo
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Di Trapani
authors.forename: Mario
authors.initials: M
authors.lastname: Sanna
mesh_terms: D018424:Cholesteatoma, Middle Ear / Q000150:complications*; D002908:Chronic Disease; D007758:Ear, Inner / Q000601:surgery; D005155:Facial Nerve Diseases / Q000209:etiology / Q000601:surgery*; D005402:Fistula / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007759:Labyrinth Diseases / Q000209:etiology / Q000601:surgery*; D020227:Lateral Sinus Thrombosis / Q000209:etiology / Q000601:surgery*; D008581:Meningitis / Q000209:etiology / Q000601:surgery*; D010033:Otitis Media / Q000150:complications*