title: Screening recipients of increased-risk donor organs: a survey of transplant infectious diseases physician practices.
abstract: BACKGROUND
  In 1994, the Public Health Service published guidelines to minimize the risk of human immunodeficiency virus (HIV) transmission and to monitor recipients following the transplantation of organs from increased-risk donors. A 2007 survey revealed the post-transplant surveillance of recipients of organs from increased-risk donors (ROIRD) is variable.
  
  
  METHODS
  An electronic survey was sent to transplant infectious diseases physicians at US solid organ transplant centers.
  
  
  RESULTS
  A total of 126 surveys were sent to infectious diseases physicians, and we received 51 (40%) responses. We found that 22% of respondents obtain only verbal, 69% verbal and written, and 8% do not obtain any special consent from ROIRD, despite an Organ Procurement and Transplantation Network policy requiring such consent. Post-solid organ transplantation serologies for HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) are performed by 6-8% of respondents in all recipients, by 69% of respondents in ROIRD only, and 25% of respondents do not perform them at all. Post-transplant nucleic acid testing is carried out by 55-64% of respondents in ROIRD, by 0-2% in all recipients, and not performed by 35-43% of respondents.
  
  
  CONCLUSIONS
  Screening RIORD for HIV, HBV, and HCV has increased since 2007, but remains less than optimal and is incomplete when screening for disease transmission at many centers.
authors.affiliation: Department of Medicine, Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; Department of Internal Medicine, Division of Infectious Diseases, The Ohio State University College of Medicine, Columbus, Ohio, USA; Northwestern University Transplant Outcomes Research Collaborative (NUTORC), Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
authors.forename: N
authors.initials: N
authors.lastname: Theodoropoulos
authors.forename: D P
authors.initials: DP
authors.lastname: Ladner
authors.forename: M G
authors.initials: MG
authors.lastname: Ison
mesh_terms: D005260:Female; D006678:HIV / Q000276:immunology / Q000302:isolation & purification*; D015658:HIV Infections / Q000517:prevention & control* / Q000635:transmission; D016174:Hepacivirus / Q000276:immunology / Q000302:isolation & purification*; D006509:Hepatitis B / Q000517:prevention & control* / Q000635:transmission; D006515:Hepatitis B virus / Q000276:immunology / Q000302:isolation & purification*; D006526:Hepatitis C / Q000517:prevention & control* / Q000635:transmission; D006801:Humans; D012306:Risk; D014019:Tissue Donors; D009927:Tissue and Organ Procurement; D014481:United States
keywords: HIV; OPTN-defined increased-risk donors; hepatitis B; hepatitis C; organ recipients; screening