title: Polyketides from the plant endophytic fungus Cladosporium sp. IFB3lp-2.
abstract: Chemical study of the ethyl acetate extract of the plant endophytic fungus Cladosporium sp. (strain no. IFB3lp-2) yielded three new polyketides (1-3), together with nine known compounds. All of the structures were elucidated on the basis of spectroscopic methods. The isolated compounds were screened for their cytotoxic, antiviral, and acetyl cholinesterase inhibitory activities. Regretfully, no compounds showed any significant activity in these assays.
authors.affiliation: a Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University , Nanjing , 210093 , China.
authors.lastname: Wuringege
authors.forename: Zhi-Kai
authors.initials: ZK
authors.lastname: Guo
authors.forename: Wei
authors.initials: W
authors.lastname: Wei
authors.forename: Rui-Hua
authors.initials: RH
authors.lastname: Jiao
authors.forename: Tong
authors.initials: T
authors.lastname: Yan
authors.forename: Le-Yun
authors.initials: LY
authors.lastname: Zang
authors.forename: Rong
authors.initials: R
authors.lastname: Jiang
authors.forename: Ren-Xiang
authors.initials: RX
authors.lastname: Tan
authors.forename: Hui-Ming
authors.initials: HM
authors.lastname: Ge
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002681:China; D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002963:Cladosporium / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D005260:Female; D045325:HCT116 Cells; D056945:Hep G2 Cells; D006801:Humans; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D018515:Plant Leaves / Q000382:microbiology; D061065:Polyketides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D043982:Rhizophoraceae / Q000382:microbiology
chemical_list: D000998:Antiviral Agents; D002800:Cholinesterase Inhibitors; D061065:Polyketides