title: Amplified detection of DNA by an analyte-induced Y-shaped junction probe assembly followed with a nicking endonuclease-mediated autocatalytic recycling process.
abstract: A simple, isothermal and autocatalytic system for the amplified detection of DNA was ingeniously designed based on target-triggered Y-shaped junction probe assembly, followed with a nicking endonuclease-mediated cascade recycling process. A superior detection limit of 0.1 pM towards the target DNA with an excellent selectivity could be achieved.
authors.affiliation: College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, 700 Changcheng Road, Qingdao 266109, China. lifeng@qust.edu.cn.
authors.forename: Shufeng
authors.initials: S
authors.lastname: Liu
authors.forename: Chengxin
authors.initials: C
authors.lastname: Zhang
authors.forename: Jingjing
authors.initials: J
authors.lastname: Ming
authors.forename: Chunfeng
authors.initials: C
authors.lastname: Wang
authors.forename: Tao
authors.initials: T
authors.lastname: Liu
authors.forename: Feng
authors.initials: F
authors.lastname: Li
mesh_terms: D001331:Automation; D015374:Biosensing Techniques; D002384:Catalysis; D004247:DNA / Q000032:analysis*; D004720:Endonucleases / Q000737:chemistry*; D005453:Fluorescence; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*
chemical_list: D004247:DNA; D004720:Endonucleases