title: Ethical and legal issues arising in research on inducing human germ cells from pluripotent stem cells.
abstract: Derivation of eggs or sperm from pluripotent stem cells or direct reprogramming from somatic cells would have huge effects on assisted reproductive technology. Here we discuss important ethical, legal, and social issues that would be raised by the development of such female or male gametes for clinical use.
authors.affiliation: Office of Health and Safety, Hokkaido University, Sapporo 060-0808, Japan. tishii@general.hokudai.ac.jp
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Ishii
authors.forename: Renee A Reijo
authors.initials: RA
authors.lastname: Pera
authors.forename: Henry T
authors.initials: HT
authors.lastname: Greely
mesh_terms: D000818:Animals; D005260:Female; D005854:Germ Cells / Q000166:cytology*; D006801:Humans; D038622:Internationality; D007564:Japan; D008297:Male; D051379:Mice; D039904:Pluripotent Stem Cells / Q000166:cytology*; D035845:Research Embryo Creation / Q000331:legislation & jurisprudence; D057905:Stem Cell Research / Q000941:ethics* / Q000331:legislation & jurisprudence*