title: Associations between piscine reovirus infection and life history traits in wild-caught Atlantic salmon Salmo salar L. in Norway.
abstract: Piscine Reovirus (PRV), the putative causative agent of heart and skeletal muscle inflammation (HSMI), is widely distributed in both farmed and wild Atlantic salmon (Salmo salar L.) in Norway. While HSMI is a common and commercially important disease in farmed Atlantic salmon, the presence of PRV has so far not been associated with HSMI related lesions in wild salmon. Factors associated with PRV-infection were investigated in returning Atlantic salmon captured in Norwegian rivers. A multilevel mixed-effect logistic regression model confirmed clustering within rivers and demonstrated that PRV-infection is associated with life-history, sex, catch-year and body length as a proxy for sea-age. Escaped farmed salmon (odds ratio/OR: 7.32, p<0.001) and hatchery-reared salmon (OR: 1.69 p=0.073) have higher odds of being PRV-infected than wild Atlantic salmon. Male salmon have double odds of being PRV infected compared to female salmon (OR: 2.11, p<0.001). Odds of being PRV-infected increased with body-length measured as decimetres (OR: 1.20, p=0.004). Since body length and sea-age are correlated (r=0.85 p<0.001), body length serves as a proxy for sea-age, meaning that spending more years in sea increases the odds of being PRV-infected.
authors.affiliation: Norwegian Veterinary Institute, P.O. Box 5695, Sluppen, NO-7485 Trondheim, Norway. ase-helen.garseth@vetinst.no
authors.forename: Ase Helen
authors.initials: AH
authors.lastname: Garseth
authors.forename: Eirik
authors.initials: E
authors.lastname: Biering
authors.forename: Arnfinn
authors.initials: A
authors.lastname: Aunsmo
mesh_terms: D000367:Age Factors; D000818:Animals; D005260:Female; D005393:Fish Diseases / Q000453:epidemiology* / Q000821:virology; D008297:Male; D008954:Models, Biological; D009664:Norway / Q000453:epidemiology; D016133:Polymerase Chain Reaction / Q000662:veterinary; D015995:Prevalence; D012367:RNA, Viral / Q000032:analysis; D012087:Reoviridae / Q000235:genetics* / Q000302:isolation & purification; D012088:Reoviridae Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D020317:Salmo salar / Q000502:physiology*; D012737:Sex Factors
chemical_list: D012367:RNA, Viral
keywords: Atlantic salmon; Disease interaction; Hierarchical; Multilevel mixed-effect model; Piscine reovirus; Sex-bias; Wild