title: [Progress of research on preparation and application of praziquantel].
abstract: Praziquantel remains the drug of choice for schistosomiasis, but it has the low bioavailability and single dosage form. This paper reviews the properties of praziquantel in vivo and in vitro, the pathogenic characteristics of schistosomiasis, and the progress of research on the formation of praziquantel, so as to enhance the efficiency of praziquantel against schistosomiasis and provide consults for relevant drug researches.
authors.affiliation: Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
authors.forename: De-Zhi
authors.initials: DZ
authors.lastname: Wu
authors.forename: Zheng
authors.initials: Z
authors.lastname: Ma
authors.forename: Yun-Feng
authors.initials: YF
authors.lastname: Liu
authors.forename: Wei-Feng
authors.initials: WF
authors.lastname: Zhu
authors.forename: An
authors.initials: A
authors.lastname: Ning
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage* / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D011223:Praziquantel / Q000008:administration & dosage* / Q000737:chemistry / Q000494:pharmacology*; D012552:Schistosomiasis / Q000188:drug therapy*
chemical_list: D000871:Anthelmintics; D011223:Praziquantel