title: Au-catalyzed formation of functionalized quinolines from 2-alkynyl arylazide derivatives.
abstract: A new method for converting 2-alkynyl arylazide derivatives into functionalized polysubstituted quinolines following a gold-catalyzed 1,3-acetoxy shift/cyclization/1,2-group shift sequence has been developed. This transformation proceeds under mild reaction conditions, is efficient, and tolerates a large variety of functional groups.
authors.affiliation: Laboratoire de Synthèse Organique, UMR 7652 CNRS/Ecole Polytechnique, Ecole Polytechnique, 91128 Palaiseau, France.
authors.forename: Colombe
authors.initials: C
authors.lastname: Gronnier
authors.forename: Guillaume
authors.initials: G
authors.lastname: Boissonnat
authors.forename: Fabien
authors.initials: F
authors.lastname: Gagosz
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D001386:Azides; D011804:Quinolines; D006046:Gold