title: Infectious aortitis in a liver transplant recipient.
abstract: The development of an abdominal aortic aneurysm secondary to infectious aortitis following solid organ transplantation is a rare event that in the absence of surgical intervention, can lead to uncontrolled sepsis, catastrophic hemorrhage and death. Arterial allografts have been a viable surgical option for the past 30 years, although operative modalities have undergone a paradigm shift in recent years. We describe the first case in the literature of a liver transplant recipient who developed an infrarenal aortic aneurysm secondary to Salmonella bacteraemia, which was treated successfully with aortic allograft transplantation.
authors.affiliation: Liver Transplant Unit, Addenbrooke's Hospital, Cambridge, UK.
authors.forename: J
authors.initials: J
authors.lastname: Gerada
authors.forename: G
authors.initials: G
authors.lastname: Ganeshanantham
authors.forename: M F
authors.initials: MF
authors.lastname: Dawwas
authors.forename: A P
authors.initials: AP
authors.lastname: Winterbottom
authors.forename: R
authors.initials: R
authors.lastname: Sivaprakasam
authors.forename: A J
authors.initials: AJ
authors.lastname: Butler
authors.forename: G J
authors.initials: GJ
authors.lastname: Alexander
mesh_terms: D000368:Aged; D001011:Aorta / Q000601:surgery; D001013:Aorta, Thoracic / Q000637:transplantation; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000601:surgery*; D001025:Aortitis / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery*; D016470:Bacteremia / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects*; D010397:Penicillanic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010878:Piperacillin / Q000627:therapeutic use; D000077725:Piperacillin, Tazobactam Drug Combination; D011859:Radiography; D012480:Salmonella Infections / Q000188:drug therapy / Q000209:etiology*; D012477:Salmonella enteritidis; D014184:Transplantation, Homologous
chemical_list: D000077725:Piperacillin, Tazobactam Drug Combination; D010397:Penicillanic Acid; D010878:Piperacillin
keywords: Aortic allograft; Salmonella enteriditis; immune suppression; infectious aortitis; liver transplantation; mycotic abdominal aortic aneurysm