title: A case of incidentally discovered subclinical cushing syndrome in a patient with chronic fatigue and anxiety.
abstract: Subclinical Cushing syndrome (SCS) is a hypothalamic-pituitary-adrenal axis abnormality characterized by autonomous cortisol secretion in patients with no typical signs or symptoms of Cushing syndrome. SCS patients may have adverse metabolic and cardiovascular effects due to slight, but continuous glucocorticoid secretion. Glucocorticoids also affect behavior, mood, neural activity, and a number of specific biochemical processes in the central nervous system. Here, we report a case of SCS due to an adrenal incidentaloma in a hypertensive diabetic patient who presented with chronic fatigue and anxiety that disappeared after the removal of the adrenal adenoma.
authors.affiliation: Department of Family Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.
authors.forename: Kyung-Jee
authors.initials: KJ
authors.lastname: Nam
authors.forename: Yun-Jin
authors.initials: YJ
authors.lastname: Kim
authors.forename: Sang-Yeoup
authors.initials: SY
authors.lastname: Lee
authors.forename: Jeong-Gyu
authors.initials: JG
authors.lastname: Lee
authors.forename: Young-Hye
authors.initials: YH
authors.lastname: Cho
authors.forename: Yu-Hyun
authors.initials: YH
authors.lastname: Lee
authors.forename: Eun-Jung
authors.initials: EJ
authors.lastname: Choi
authors.forename: Young-Jin
authors.initials: YJ
authors.lastname: Tak
authors.forename: Dong-Won
authors.initials: DW
authors.lastname: Yi
authors.forename: Sung-Woo
authors.initials: SW
authors.lastname: Park
authors.forename: Dong-Wook
authors.initials: DW
authors.lastname: Jeong
keywords: Adrenal Incidentaloma; Anxiety; Chronic Fatigue; Subclinical Cushing Syndrome
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