title: [Mixed squamous and glandular papilloma].
abstract: The patient was a 64-year-old man. He had a smoking history for 43 years (20 cigarettes per day). Being pointed out a mass shadow in the left lower lung field on chest X-ray in a regular checkup, he was referred to our hospital. The chest computed tomography (CT) revealed a tumor shadow of 30 mm diameter in the left S8. Blood tests showed that carcinoembryonic antigen (CEA) and squamous cell carcinoma-related antigen (SCC) were elevated. Accumulation of standardized uptake value (SUV) max 9.78/15.17 match the tumor shadow in fluorodeoxyglucose positron emission tomography (FDGPET),suspected of malignancy. As a result of bronchoscopy, squamous cell carcinoma was suspected by cytology, and he was introduced to us for surgery. Video-assisted thoracic surgery (VATS)-left lower lobectomy and lymph node dissection was performed. By pathology, the tumor showed papillary growth in peripheral bronchus, with squamous cell and high columnar epithelial cell components. The tumor was diagnosed as mixed squamous and glandulas papilloma. In addition, a part of the squamous cells was considered to be atypical, indicating squamous cell carcinoma in situ in a mixed epithelial and glandular papilloma.
authors.affiliation: Department of Thoracic Surgery, Tohoku Phermaceutical University Hospital, Sendai, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yabuki
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Tabata
authors.forename: Takafumi
authors.initials: T
authors.lastname: Sugawara
authors.forename: Ken
authors.initials: K
authors.lastname: Fukaya
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Murakami
authors.forename: Shigefumi
authors.initials: S
authors.lastname: Fujimura
mesh_terms: D002278:Carcinoma in Situ / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000473:pathology*; D010212:Papilloma / Q000473:pathology*