title: [Nano-electrospray ionization-ion mobility spectrometry and its combination with high performance liquid chromatography].
abstract: A nano-electrospray ionization-ion mobility spectrometer (nanoESI-IMS) was built up. Firstly, the effects of the parameters such as drift gas flow rate and solvent flow rate on the desolvation capability were studied and optimized. Then, a series of compounds were used to characterize the nanoESI-IMS system. The results showed that, complete desolvation was achieved for nano-electrospray ion droplets with the nanoESI-IMS apparatus. The limit of detection of this instrument for trioctylamine could reach 10 microg/L. Finally, this instrument was coupled to the high performance liquid chromatography (HPLC) as a detector for amines analysis. A test mixture containing triethylamine, diethylamine and butylamine was successfully separated and determined by the HPLC-nanoESI-IMS system. Linear response ranges of about two orders of magnitude were achieved for triethylamine, diethylamine and butylamine with this system.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
authors.forename: Chuang
authors.initials: C
authors.lastname: Chen
authors.forename: Weiguo
authors.initials: W
authors.lastname: Wang
authors.forename: Xixi
authors.initials: X
authors.lastname: Liang
authors.forename: Qinghu
authors.initials: Q
authors.lastname: Zhou
authors.forename: Liying
authors.initials: L
authors.lastname: Peng
authors.forename: Meng
authors.initials: M
authors.lastname: Wen
authors.forename: Bangyu
authors.initials: B
authors.lastname: Ju
authors.forename: Kun
authors.initials: K
authors.lastname: Zhao
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.forename: Haiyang
authors.initials: H
authors.lastname: Li