title: Pulmonary hyalinizing granuloma detected in a family member after confirmation of tuberculosis in his father.
abstract: Pulmonary hyalinizing granuloma (PHG) is an uncommon lung disease that usually presents as bilateral multiple nodules, and more rarely as a solitary nodule. An exaggerated immune response to antigenic stimuli resulting from infection or an autoimmune process has been suggested as the cause of PHG. Here, we describe a rare case of solitary PHG that was detected in a family member after tuberculosis had been confirmed in his father, without any background of infectious disease or autoimmune abnormality.
authors.affiliation: Department of Thoracic Surgery, National Hospital Organization Himeji Medical Center, Hyogo, Japan.
authors.forename: Katsunari
authors.initials: K
authors.lastname: Matsuoka
authors.forename: Naoko
authors.initials: N
authors.lastname: Imanishi
authors.forename: Takahisa
authors.initials: T
authors.lastname: Matsuoka
authors.forename: Shinjiro
authors.initials: S
authors.lastname: Nagai
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Ueda
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Miyamoto
mesh_terms: D000328:Adult; D058070:Asymptomatic Diseases; D001706:Biopsy; D005220:Fathers; D015769:Granuloma, Respiratory Tract / Q000175:diagnosis* / Q000276:immunology / Q000378:metabolism / Q000382:microbiology / Q000601:surgery; D006801:Humans; D006818:Hyalin; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D009169:Mycobacterium tuberculosis / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity*; D011013:Pneumonectomy / Q000379:methods; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis* / Q000276:immunology / Q000378:metabolism / Q000382:microbiology / Q000601:surgery; D020775:Thoracic Surgery, Video-Assisted; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology / Q000635:transmission