title: Neonatal pleural empyema caused by emm type 6 group A streptococcus.
abstract: Since the mid-1980s, there have been increasing reports of severe invasive group A streptococcal (GAS) disease in children and adults. There are few reports, however, of neonatal invasive disease, particularly neonatal pleural empyema caused by GAS. Although many mechanisms have been reported for the pathophysiology of invasive GAS infections, similar reports for neonates were unable to be located. Reported herein is the case of a 3-day-old girl with pleural empyema caused by GAS that demonstrated a high invasive capacity for human epithelial cells.
authors.affiliation: Department of Pediatrics, Asahikawa Medical University, Hokkaido, Japan. nohara@asahikawamed.ac.jp
authors.forename: Fumikatsu
authors.initials: F
authors.lastname: Nohara
authors.forename: Ken
authors.initials: K
authors.lastname: Nagaya
authors.forename: Hiroko
authors.initials: H
authors.lastname: Asai
authors.forename: Etsushi
authors.initials: E
authors.lastname: Tsuchida
authors.forename: Toshio
authors.initials: T
authors.lastname: Okamoto
authors.forename: Tokitsugi
authors.initials: T
authors.lastname: Hayashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sakata
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Terao
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Azuma
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000942:Antigens, Bacterial / Q000276:immunology*; D016724:Empyema, Pleural / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D013290:Streptococcal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000276:immunology* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D000942:Antigens, Bacterial
keywords: neonate; pleural empyema; streptococcus group A