title: Rhombencephalitis caused by Francisella tularensis.
abstract: Common presentations of tularemia include pneumonia and ulceroglandular, oropharyngeal, or typhoidal disease. Neuromeningeal involvement is extremely rare. We report a case of a severe rhombencephalitis due to Francisella tularensis. Diagnosis was possible thanks to a very precise interview, and the patient dramatically improved after specific antibiotherapy.
authors.affiliation: Infectious Disease and Intensive Care Unit, CHU, Rennes, France.
authors.forename: M
authors.initials: M
authors.lastname: Barbaz
authors.forename: C
authors.initials: C
authors.lastname: Piau
authors.forename: J M
authors.initials: JM
authors.lastname: Tadie
authors.forename: I
authors.initials: I
authors.lastname: Pelloux
authors.forename: S
authors.initials: S
authors.lastname: Kayal
authors.forename: P
authors.initials: P
authors.lastname: Tattevin
authors.forename: Y
authors.initials: Y
authors.lastname: Le Tulzo
authors.forename: M
authors.initials: M
authors.lastname: Revest
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging; D004660:Encephalitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D005604:Francisella tularensis / Q000302:isolation & purification*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011859:Radiography; D016896:Treatment Outcome; D014406:Tularemia / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*
chemical_list: D000900:Anti-Bacterial Agents
references.citation: Clin Infect Dis. 2012 Nov 15;55(10):1283-90
references.pmid: 22911645
references.citation: Clin Infect Dis. 2011 Nov;53(10):e133-41
references.pmid: 22002987
references.citation: Clin Infect Dis. 2009 May 1;48(9):1266-7, 1327-8
references.pmid: 19344255
references.citation: Clin Infect Dis. 2009 Dec 15;49(12):1838-47
references.pmid: 19929384
references.citation: Clin Microbiol Rev. 2002 Oct;15(4):631-46
references.pmid: 12364373
references.citation: Arch Neurol. 2009 Apr;66(4):523-7
references.pmid: 19364939
references.citation: Int J Antimicrob Agents. 2007 Oct;30(4):297-308
references.pmid: 17629679
references.citation: Am J Pathol. 1932 Jan;8(1):57-62.3
references.pmid: 19969998
references.citation: Infect Immun. 1995 Apr;63(4):1478-83
references.pmid: 7890413