title: A Munc13-like protein in Arabidopsis mediates H+-ATPase translocation that is essential for stomatal responses.
abstract: Plants control CO2 uptake and water loss by modulating the aperture of stomata located in the epidermis. Stomatal opening is initiated by the activation of H(+)-ATPases in the guard-cell plasma membrane. In contrast to regulation of H(+)-ATPase activity, little is known about the translocation of the guard cell H(+)-ATPase to the plasma membrane. Here we describe the isolation of an Arabidopsis gene, PATROL1, that controls the translocation of a major H(+)-ATPase, AHA1, to the plasma membrane. PATROL1 encodes a protein with a MUN domain, known to mediate synaptic priming in neuronal exocytosis in animals. Environmental stimuli change the localization of plasma membrane-associated PATROL1 to an intracellular compartment. Plasma membrane localization of AHA1 and stomatal opening require the association of PATROL1 with AHA1. Increased stomatal opening responses in plants overexpressing PATROL1 enhance the CO2 assimilation rate, promoting plant growth.
authors.affiliation: Department of Biology, Faculty of Sciences, Kyushu University, Fukuoka 812-8581, Japan.
authors.forename: Mimi
authors.initials: M
authors.lastname: Hashimoto-Sugimoto
authors.forename: Takumi
authors.initials: T
authors.lastname: Higaki
authors.forename: Takashi
authors.initials: T
authors.lastname: Yaeno
authors.forename: Ayako
authors.initials: A
authors.lastname: Nagami
authors.forename: Mari
authors.initials: M
authors.lastname: Irie
authors.forename: Miho
authors.initials: M
authors.lastname: Fujimi
authors.forename: Megumi
authors.initials: M
authors.lastname: Miyamoto
authors.forename: Kae
authors.initials: K
authors.lastname: Akita
authors.forename: Juntaro
authors.initials: J
authors.lastname: Negi
authors.forename: Ken
authors.initials: K
authors.lastname: Shirasu
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Hasezawa
authors.forename: Koh
authors.initials: K
authors.lastname: Iba
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000235:genetics* / Q000378:metabolism; D002245:Carbon Dioxide / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D018832:Molecular Chaperones / Q000235:genetics* / Q000378:metabolism; D054046:Plant Stomata / Q000235:genetics* / Q000378:metabolism; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D021381:Protein Transport; D006180:Proton-Translocating ATPases / Q000235:genetics* / Q000378:metabolism; D014867:Water / Q000378:metabolism
chemical_list: D029681:Arabidopsis Proteins; D018832:Molecular Chaperones; C585961:PATROL1 protein, Arabidopsis; D014867:Water; D002245:Carbon Dioxide; D006180:Proton-Translocating ATPases; C544444:AHA1 protein, Arabidopsis
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