title: Aneurysms of medium-sized arteries in Marfan syndrome.
abstract: Marfan syndrome is a relatively common connective tissue disorder that causes skin, ocular, skeletal, and cardiovascular abnormalities. High morbidity and mortality occur with aortic aneurysm and dissection. Other large-artery aneurysms, including carotid, subclavian, and iliac artery aneurysms, have also been associated with Marfan syndrome. It is not clear whether small- to medium-sized artery aneurysms are associated with Marfan syndrome. This report describes 4 patients with Marfan syndrome who have associated small- to medium-sized artery aneurysms with several complications. Additional investigations are needed to determine whether Marfan syndrome can cause small- to medium-sized artery aneurysms and how patients with these aneurysms should be treated.
authors.affiliation: University of Michigan Cardiovascular Center, Ann Arbor, MI. Electronic address: mazena@med.umich.edu.
authors.forename: Mazen
authors.initials: M
authors.lastname: Awais
authors.forename: David M
authors.initials: DM
authors.lastname: Williams
authors.forename: G Michael
authors.initials: GM
authors.lastname: Deeb
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Shea
mesh_terms: D000328:Adult; D000783:Aneurysm / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D002445:Celiac Artery / Q000000981:diagnostic imaging; D004621:Embolization, Therapeutic; D005260:Female; D024405:Gastroepiploic Artery / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008323:Mammary Arteries / Q000000981:diagnostic imaging; D008382:Marfan Syndrome / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D017535:Ulnar Artery / Q000000981:diagnostic imaging