title: [Effect of melatonin on the thrombocyte hemostasis and its circadian organization].
abstract: Melatonin produced by pineal gland and some peripheral cells effect both spontaneous and induced aggregation of platelets. As a natural inhibitor of aggregation, melatonin limits hemostasis in night hours. A decrease in the plasma level of melatonin in early morning hours is probably responsible for cardiovascular disorders and may be recommended for use in pharmacotherapy.
authors.forename: É B
authors.initials: ÉB
authors.lastname: Arushanian
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000378:metabolism* / Q000503:physiopathology*; D002940:Circadian Rhythm; D006487:Hemostasis; D006801:Humans; D008550:Melatonin / Q000378:metabolism*
chemical_list: D008550:Melatonin