title: [Endoscopic endonasal detection of cerebrospinal fluid leakage with topical fluorescein].
abstract: We evaluated the effectiveness of intraoperative topical application of fluorescein to detect the leakage point of cerebrospinal fluid(CSF)rhinorrhea. Three patients with CSF rhinorrhea were treated with an endoscopic endonasal technique. Ten percent fluorescein was topically used for intraoperative localization of the leak site. A change of the fluorescein color from brown to green due to dilation of CSF were recognized as evidence of CSF rhinorrhea. We repeated the procedure to detect any small defects. All CSF rhinorrheas were successfully repaired by this endoscopic endonasal approach. Topical application of fluorescein is simple and sensitive for identifying intraoperative CSF rhinorrhea.
authors.affiliation: Department of Neurosurgery, Fukushima Medical University.
authors.forename: Taku
authors.initials: T
authors.lastname: Sato
authors.forename: Yugo
authors.initials: Y
authors.lastname: Kishida
authors.forename: Tadashi
authors.initials: T
authors.lastname: Watanabe
authors.forename: Akiko
authors.initials: A
authors.lastname: Tani
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Tada
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Tamura
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ichikawa
authors.forename: Jun
authors.initials: J
authors.lastname: Sakuma
authors.forename: Koichi
authors.initials: K
authors.lastname: Omori
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Saito
mesh_terms: D000328:Adult; D000368:Aged; D002559:Cerebrospinal Fluid Rhinorrhea / Q000175:diagnosis / Q000601:surgery*; D004724:Endoscopy / Q000379:methods; D005260:Female; D019793:Fluorescein; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D016896:Treatment Outcome
chemical_list: D019793:Fluorescein