title: Analysis and perspective of Dosing accuracy and insulin flow rate characteristics of a new disposable insulin pen, FlexTouch, compared with SoloSTAR.
abstract: Pen injectors for the administration of insulin have been available since the 1980s. The first insulin pen, NovoPen®, was introduced by Novo in 1985 (http://www.novonordisk.com/about_us/history/step-by-step.asp). In the years since, insulin pens have seen innovation in both features and functionality, and many more manufacturers have entered the market. This analysis discusses several features and design alternatives of insulin pens and comments on a new study by Bohnet and coauthors in this issue of Journal of Diabetes Science and Technology that compared the dosing accuracy of the spring-driven FlexTouch® (FT; Novo Nordisk; insulin aspart) with that of the manually operated SoloSTAR® (Sanofi; insulin glulisine). The volumetric flow rate of insulin delivery with FT was also evaluated.
authors.affiliation: Eli Lilly and Company, Lilly Corporate Center DC, Indianapolis, IN 46285, USA. yeager_harold_k@lilly.com
authors.forename: Harold K
authors.initials: HK
authors.lastname: Yeager
authors.forename: Debra A
authors.initials: DA
authors.lastname: Ignaut
mesh_terms: D004209:Disposable Equipment; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007328:Insulin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D061267:Insulin Aspart / Q000008:administration & dosage*; D007332:Insulin Infusion Systems
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin; C479079:insulin glulisine; D061267:Insulin Aspart
references.citation: J Diabetes Sci Technol. 2011 Jan 01;5(1):150-5
references.pmid: 21303637
references.citation: J Diabetes Sci Technol. 2013 Jul 01;7(4):1021-6
references.pmid: 23911185