title: [Microsurgical management of adult brainstem gliomas under the DTI and intraoperative nuclei mapping: a retrospective analysis of 19 cases].
abstract: OBJECTIVE
  To explore the role of DTI-Tractography and intraoperative nuclei mapping in microsurgery of adult brainstem gliomas.
  
  
  METHODS
  Nineteen patients with adult brainstem gliomas were recruited for this study in our hospital from 2010 to 2012. The role of DTI-Tractography and intraoperative nuclei mapping in the microsurgery was retrospectively reviewed.
  
  
  RESULTS
  Two patients underwent almost total resection, while 11 patents underwent subtotal resection and 6 patients underwent partial resection. Neurological functions improved or remained stable in 14 patients (73.7%) after surgery; whereas, 5 patients (26.3%) experienced deteriorated or transitory new symptoms. Follow-up visits found that 17 patients (89.5%)had improved or stable neurological functions.
  
  
  CONCLUSIONS
  DTI-Tractography and intraoperative nuclei mapping provides great support to the choice of surgical approach and the determination of degree of resection. It helps achieve maximal safe resection of adult brainstem gliomas.
authors.affiliation: Department of Anesthesiology Pain Management of Ward, West China Hospital, Sichuan University, Chengdu 610041, China. liuli-hsy@163.com
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.forename: Xu-Hui
authors.initials: XH
authors.lastname: Hui
authors.forename: Si
authors.initials: S
authors.lastname: Zhang
authors.forename: Yuan
authors.initials: Y
authors.lastname: Fang
authors.forename: Yue-Kang
authors.initials: YK
authors.lastname: Zhang
authors.forename: Xu-Ping
authors.initials: XP
authors.lastname: Xie
mesh_terms: D000293:Adolescent; D000328:Adult; D001931:Brain Mapping / Q000379:methods*; D020295:Brain Stem Neoplasms / Q000601:surgery*; D056324:Diffusion Tensor Imaging / Q000379:methods*; D005260:Female; D005910:Glioma / Q000601:surgery*; D006801:Humans; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D056347:Neuroanatomical Tract-Tracing Techniques / Q000379:methods; D038361:Neuronavigation / Q000379:methods; D019635:Neurosurgical Procedures / Q000379:methods; D012189:Retrospective Studies; D055815:Young Adult