title: Measurement properties of the Work Limitations Questionnaire were sufficient among cancer survivors.
abstract: OBJECTIVE
  The purpose of this study was to determine reproducibility, validity, and responsiveness of the Work Limitations Questionnaire (WLQ) among cancer survivors.
  
  
  METHODS
  A cohort of 53 cancer survivors completed the WLQ and other questionnaires at baseline, 4-week, and 6-month follow-up. We assessed internal consistency, intraclass correlation coefficient, standard error of measurement, floor- and ceiling effects and compared the WLQ with other constructs. For responsiveness, we assessed the following anchor-based measures: minimal important change (MIC) versus smallest detectable change (SDC) and area under the curve (AUC) of receiver operation characteristic (ROC).
  
  
  RESULTS
  We found sufficient reproducibility at group level but not at individual level as the MIC (4.0) exceeded SDC at group level (3.1) but not at individual level (18.0). There was no indication of systematic bias or proportional bias. The internal consistency and construct validity for the WLQ and its subscales were sufficient or slightly less than sufficient. There was a floor effect for one subscale, but there were no ceiling effects. Responsiveness was sufficient with an AUC of a ROC of 0.65.
  
  
  CONCLUSIONS
  The WLQ is reproducible, valid, and responsive for use at group level among cancer survivors but not sufficiently reproducible for use at individual level.
authors.affiliation: Coronel Institute of Occupational Health, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE, Amsterdam, The Netherlands, s.j.tamminga@amc.nl.
authors.forename: Sietske J
authors.initials: SJ
authors.lastname: Tamminga
authors.forename: Jos H A M
authors.initials: JH
authors.lastname: Verbeek
authors.forename: Monique H W
authors.initials: MH
authors.lastname: Frings-Dresen
authors.forename: Angela G E M
authors.initials: AG
authors.lastname: De Boer
mesh_terms: D000328:Adult; D019540:Area Under Curve; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000503:physiopathology* / Q000523:psychology*; D009426:Netherlands; D009790:Occupations / Q000706:statistics & numerical data; D011446:Prospective Studies; D011788:Quality of Life; D012372:ROC Curve; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D017741:Survivors / Q000523:psychology*; D014937:Work / Q000706:statistics & numerical data*
references.citation: Lancet. 1986 Feb 8;1(8476):307-10
references.pmid: 2868172
references.citation: J Clin Epidemiol. 2008 Feb;61(2):102-9
references.pmid: 18177782
references.citation: J Occup Environ Med. 2012 Oct;54(10):1293-9
references.pmid: 22995808
references.citation: Med Care. 2000 Sep;38(9 Suppl):II84-90
references.pmid: 10982093
references.citation: J Rheumatol. 2005 Jun;32(6):1006-12
references.pmid: 15940759
references.citation: J Clin Epidemiol. 2010 May;63(5):524-34
references.pmid: 19926446
references.citation: Scand J Work Environ Health. 1992;18 Suppl 2:8-10
references.pmid: 1514096
references.citation: Phys Ther. 2011 Feb;91(2):254-66
references.pmid: 21212376
references.citation: Scand J Work Environ Health. 2012 Jan;38(1):5-18
references.pmid: 21874208
references.citation: Occup Med (Lond). 2002 Jun;52(4):177-81
references.pmid: 12091582
references.citation: J Clin Epidemiol. 2007 Jan;60(1):34-42
references.pmid: 17161752
references.citation: J Occup Environ Med. 2008 Jul;50(7):777-84
references.pmid: 18617833
references.citation: Eur J Cancer. 2003 Jul;39(11):1562-7
references.pmid: 12855263
references.citation: J Occup Environ Med. 2001 Mar;43(3):218-25
references.pmid: 11285869
references.citation: J Rehabil Med. 2011 Jan;43(1):23-31
references.pmid: 21103849
references.citation: J Occup Environ Med. 2007 Jul;49(7):803-11
references.pmid: 17622854
references.citation: Med Care. 2001 Jan;39(1):72-85
references.pmid: 11176545
references.citation: J Clin Epidemiol. 2006 Oct;59(10):1033-9
references.pmid: 16980142
references.citation: BMC Med Res Methodol. 2011 Jun 06;11:87
references.pmid: 21645355
references.citation: JAMA. 2009 Feb 18;301(7):753-62
references.pmid: 19224752
references.citation: Qual Life Res. 2004 Mar;13(2):311-20
references.pmid: 15085903
references.citation: Psychooncology. 2002 Mar-Apr;11(2):124-31
references.pmid: 11921328
references.citation: Br J Cancer. 1990 Dec;62(6):1034-8
references.pmid: 2257209
references.citation: Psychooncology. 2008 Jan;17(1):91-7
references.pmid: 17429835
references.citation: J Cancer Surviv. 2008 Dec;2(4):296-302
references.pmid: 19003541
references.citation: Arthritis Care Res (Hoboken). 2010 Jan 15;62(1):28-37
references.pmid: 20191488
references.citation: Anesth Analg. 2000 Mar;90(3):593-602
references.pmid: 10702443
references.citation: Health Technol Assess. 2007 Dec;11(50):iii, ix-51
references.pmid: 18021577