title: Catalytic 1,4-selective hydrosilylation of pyridines and benzannulated congeners.
abstract: Radically different! The hydrosilylation of pyridines and quinolines is strictly 1,4-selective and likely involves an ionic one-step rather than the established radical two-step hydride transfer from a ruthenium(II) hydride complex onto the respective pyridinium and quinolinium ion intermediates (see scheme; Ar(F) =3,5-(CF3)2C6H3). Even 4-substituted substrates react highly regioselectively. Isoquinolines yield the 1,2-reduced heterocycles.
authors.affiliation: Institut für Chemie, Technische Universität Berlin, Strasse des 17. Juni 115, 10623 Berlin (Germany) http://www.organometallics.tu-berlin.de.
authors.forename: C David F
authors.initials: CD
authors.lastname: Königs
authors.forename: Hendrik F T
authors.initials: HF
authors.lastname: Klare
authors.forename: Martin
authors.initials: M
authors.lastname: Oestreich
mesh_terms: D002384:Catalysis; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D012821:Silanes / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D011725:Pyridines; D012821:Silanes
keywords: N-heterocycles; SiH bond activation; homogeneous catalysis; hydrosilylation; regioselectivity