title: Treatment outcomes of chemical castration on Korean sex offenders.
abstract: After the recent enactment of the chemical castration legislation for sex offenders in Korea, we sought to report primary treatment outcomes for 38 patients at the National Forensic Hospital since 2011. After chemical castration, these patients experienced reductions in frequency and intensity of sexual drive, frequency of masturbation and sexual fantasies. The incidence of adverse effects was similar to that of previous reports. Serial hormonal evaluations showed an association between testosterone level and degree of paraphilic and non-paraphilic sexual thoughts. A notable finding was an unexpected upsurge of testosterone levels with intense sexual drive and fantasy observed during the first 2 months after cessation of treatment. This suggested the need for a temporary anti-androgen therapy or close surveillance during this period. When proper precautions are taken, chemical castration may be an effective treatment strategy for paraphilic and non-paraphilic sex offenders.
authors.affiliation: Department of Urology and Urological Science Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, South Korea. gckoo@yuhs.ac
authors.forename: Kyo Chul
authors.initials: KC
authors.lastname: Koo
authors.forename: Geum Sook
authors.initials: GS
authors.lastname: Shim
authors.forename: Hyoun Hee
authors.initials: HH
authors.lastname: Park
authors.forename: Koon Ho
authors.initials: KH
authors.lastname: Rha
authors.forename: Young Deuk
authors.initials: YD
authors.lastname: Choi
authors.forename: Byung Ha
authors.initials: BH
authors.lastname: Chung
authors.forename: Sung Joon
authors.initials: SJ
authors.lastname: Hong
authors.forename: Jae Woo
authors.initials: JW
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D000726:Androgen Antagonists / Q000008:administration & dosage* / Q000009:adverse effects; D003430:Cross-Sectional Studies; D003692:Delayed-Action Preparations; D006801:Humans; D007279:Injections, Subcutaneous; D016729:Leuprolide / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010262:Paraphilic Disorders / Q000188:drug therapy* / Q000523:psychology; D011446:Prospective Studies; D056910:Republic of Korea; D011795:Surveys and Questionnaires; D013739:Testosterone / Q000097:blood; D055815:Young Adult
chemical_list: D000726:Androgen Antagonists; D003692:Delayed-Action Preparations; D013739:Testosterone; D016729:Leuprolide
keywords: Castration; Paraphilia; Testosterone