title: Toxic effects of the interaction of titanium dioxide nanoparticles with chemicals or physical factors.
abstract: Due to their chemical stability and nonallergic, nonirritant, and ultraviolet protective properties, titanium dioxide (TiO2) nanoparticles (NPs) have been widely used in industries such as electronics, optics, and material sciences, as well as architecture, medicine, and pharmacology. However, increasing concerns have been raised in regards to its ecotoxicity and toxicity on the aquatic environment as well as to humans. Although insights have been gained into the effects of TiO2 NPs on susceptible biological systems, there is still much ground to be covered, particularly in respect of our knowledge of the effects of the interaction of TiO2 NPs with other chemicals or physical factors. Studies suggest that interactions of TiO2 NPs with other chemicals or physical factors may result in an increase in toxicity or adverse effects. This review highlights recent progress in the study of the interactive effects of TiO2 NPs with other chemicals or physical factors.
authors.affiliation: Public Health Department of Medical School, Zhejiang Provincial Key Laboratory of Pathological and Physiological Technology, Ningbo University, Ningbo, Zhejiang Province, People's Republic of China.
authors.forename: Kui
authors.initials: K
authors.lastname: Liu
authors.forename: Xialu
authors.initials: X
authors.lastname: Lin
authors.forename: Jinshun
authors.initials: J
authors.lastname: Zhao
mesh_terms: D000818:Animals; D001559:Benzhydryl Compounds; D054750:Ecotoxicology; D006801:Humans; D006843:Hydrocarbons, Chlorinated; D053768:Metal Nanoparticles; D008670:Metals; D051379:Mice; D010599:Pharmacokinetics; D010636:Phenols; D014025:Titanium; D014466:Ultraviolet Rays; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D006843:Hydrocarbons, Chlorinated; D008670:Metals; D010636:Phenols; D014025:Titanium; C009495:titanium dioxide; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: TiO2; chemicals; interaction; nanoparticles; physical factors; titanium dioxide
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