title: [The clinical value of combining multiple features of CT in discriminating between benign and malignant lung lesions].
abstract: OBJECTIVE
  To develop a set of combined criteria of multiple features of chest CT for discriminating between benign and malignant lung lesions.
  
  
  METHODS
  Patients whose chest CT showed abnormalities were recruited from the West China Hospital in March and April 2010. The patients were examined with bronchoscopy and the results of CT and pathology were compared.
  
  
  RESULTS
  A total of 105 patients participated in this study and 85 had confirmed pathological results. The CT identified 27 cases of malignant lesions, 22 of which were confirmed by the pathology. The CT identified 58 cases of benign lesions, 55 of which were confirmed by the pathology. The set of combined criteria of multiple features of chest CT had an accuracy of 90.59%, a sensitivity of 88.00%, and a specificity of 91.67% in diagnosing benign and malignant lung lesions.
  
  
  CONCLUSIONS
  The combined criteria of multiple imaging signs of CT have good clinical values for diagnosing malignant lung lesions.
authors.affiliation: Department of Respiratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Wei
authors.initials: W
authors.lastname: He
authors.forename: Subhash
authors.initials: S
authors.lastname: Yogi
authors.forename: De-Yun
authors.initials: DY
authors.lastname: Cheng
authors.forename: Nikunj
authors.initials: N
authors.lastname: Yogi
authors.forename: Jian-Qun
authors.initials: JQ
authors.lastname: Yu
authors.forename: Xue-Ming
authors.initials: XM
authors.lastname: Li
authors.forename: Ting
authors.initials: T
authors.lastname: Li
authors.forename: Dai-Yun
authors.initials: DY
authors.lastname: Chen
authors.forename: Xue-Ying
authors.initials: XY
authors.lastname: Su
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D001999:Bronchoscopy / Q000379:methods; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging* / Q000473:pathology; D036542:Tomography, Spiral Computed / Q000379:methods*; D055815:Young Adult