title: Comparative study on effects of dietary with diphenyl diselenide on oxidative stress in carp (Cyprinus carpio) and silver catfish (Rhamdia sp.) exposed to herbicide clomazone.
abstract: The study investigated the capacity of diphenyl diselenide [(PhSe)2] (3.0mg/kg), on reduce the oxidative damage in liver, gills and muscle of carp and silver catfish exposed to clomazone (192h). Silver catfish exposed to clomazone showed increased thiobarbituric acid-reactive substance (TBARS) in liver and muscle and protein carbonyl in liver and gills. Furthermore, clomazone in silver catfish decrease non-protein thiols (NPSH) in liver and gills and glutathione peroxidase and ascorbic acid in liver. (PhSe)2 reversed the effects caused by clomazone in silver catfish, preventing increases in TBARS and protein carbonyl. Moreover, NPSH and ascorbic acid were increased by values near control. The results suggest that (PhSe)2 attenuated the oxidative damage induced by clomazone in silver catfish. The clomazone no caused an apparent situation of oxidative stress in carp, showing that this species is more resistant to this toxicant. Altogether, the containing (PhSe)2 diet helps fish to increase antioxidants defenses.
authors.affiliation: Programa de Pós-Graduação em Bioquímica Toxicológica, Departamento de Química, Brazil; Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
authors.forename: Charlene
authors.initials: C
authors.lastname: Menezes
authors.affiliation: Programa de Pós-Graduação em Bioquímica Toxicológica, Departamento de Química, Brazil; Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
authors.forename: Jossiele
authors.initials: J
authors.lastname: Leitemperger
authors.affiliation: Programa de Pós-Graduação em Farmacologia e Fisiologia, Departamento de Fisiologia e Farmacologia, Brazil; Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
authors.forename: Cândida
authors.initials: C
authors.lastname: Toni
authors.affiliation: Programa de Pós-Graduação em Bioquímica Toxicológica, Departamento de Química, Brazil; Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
authors.forename: Adriana
authors.initials: A
authors.lastname: Santi
authors.affiliation: Programa de Pós-Graduação em Bioquímica Toxicológica, Departamento de Química, Brazil; Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
authors.forename: Thais
authors.initials: T
authors.lastname: Lópes
authors.affiliation: Programa de Pós-Graduação em Bioquímica Toxicológica, Departamento de Química, Brazil; Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
authors.forename: Nilda Berenice Vargas
authors.initials: NBV
authors.lastname: Barbosa
authors.affiliation: Programa de Pós-Graduação em Zootecnia, Departamento de Zootecnia, Brazil; Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
authors.forename: João Radünz
authors.initials: JR
authors.lastname: Neto
authors.affiliation: Programa de Pós-Graduação em Bioquímica Toxicológica, Departamento de Química, Brazil; Universidade Federal de Santa Maria, Santa Maria, RS, Brazil. Electronic address: vania.loro@gmail.com.
authors.forename: Vania Lucia
authors.initials: VL
authors.lastname: Loro
mesh_terms: D000821:Animal Feed; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001205:Ascorbic Acid / Q000378:metabolism; D001555:Benzene Derivatives / Q000494:pharmacology*; D002347:Carps / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D002397:Catfishes / Q000378:metabolism*; D004032:Diet; D019587:Dietary Supplements; D005880:Gills / Q000187:drug effects / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D006540:Herbicides / Q000633:toxicity*; D007555:Isoxazoles / Q000633:toxicity*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D009132:Muscles / Q000187:drug effects / Q000378:metabolism; D016566:Organoselenium Compounds / Q000494:pharmacology*; D023303:Oxazolidinones / Q000633:toxicity*; D018384:Oxidative Stress / Q000187:drug effects*; D050050:Protein Carbonylation / Q000187:drug effects; D013045:Species Specificity; D013438:Sulfhydryl Compounds / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D000975:Antioxidants; D001555:Benzene Derivatives; D006540:Herbicides; D007555:Isoxazoles; D016566:Organoselenium Compounds; D023303:Oxazolidinones; D013438:Sulfhydryl Compounds; D017392:Thiobarbituric Acid Reactive Substances; D014874:Water Pollutants, Chemical; C061132:diphenyldiselenide; C095255:clomazone; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005982:Glutathione Transferase; D001205:Ascorbic Acid
keywords: Antioxidant; Fish; Oxidative damage; Pesticide; Selenium