title: The efficacy and safety of modified Snyder-Thompson posterior scleral reinforcement in extensive high myopia of Chinese children.
abstract: BACKGROUND
  To observe the efficacy and safety of modified Snyder-Thompson posterior scleral reinforcement in extensive high myopia of Chinese children. We had a retrospective design, and included a control group of children with natural progression of high myopia.
  
  
  METHODS
  This study included 64 eyes in 41 Chinese children with extensive high myopia who underwent modified Snyder-Thompson posterior scleral reinforcement surgery (PSR group), and 17 eyes in 11 age- and myopia-matched children who wore spectacles (control group). The mean follow-up was 4.99 ± 1.3 years in the PSR group and 4.48 ± 1.3 years in the control group. Axial length, spherical equivalent (SE), uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA) and fundus examinations were recorded before and after treatment, and complications were noted.
  
  
  RESULTS
  The mean change in SE at the end of the follow-up period was 1.5 ± 1.44 diopters (D) and 3.02 ± 1.57D in the PSR and control groups respectively. These changes were equivalent to an increase in axial length of 1.27 ± 0.54 mm and 2.05 ± 0.91 mm respectively. The PSR group showed less myopic progression and less eye elongation (p < 0.001). A notable increase in UCVA was only found in the PSR group (p = 0.0001). The improvement in BCVA was significantly greater in the PSR group (p = 0.0354). There were no serious complications of PSR surgery.
  
  
  CONCLUSIONS
  The modified Snyder-Thompson PSR surgery was effective and safe in controlling extensive high myopia of Chinese children.
authors.affiliation: Department of Ophthalmology, EYE and ENT Hospital of Fudan University, No.83, Fenyang Road, Shanghai, 200031, China.
authors.forename: Minjie
authors.initials: M
authors.lastname: Chen
authors.forename: Jinhui
authors.initials: J
authors.lastname: Dai
authors.forename: Renyuan
authors.initials: R
authors.lastname: Chu
authors.forename: Yifeng
authors.initials: Y
authors.lastname: Qian
mesh_terms: D044466:Asian People; D058452:Axial Length, Eye / Q000473:pathology; D002648:Child; D018450:Disease Progression; D004388:Dura Mater / Q000637:transplantation*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D047728:Myopia, Degenerative / Q000208:ethnology / Q000601:surgery*; D013508:Ophthalmologic Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D012189:Retrospective Studies; D012590:Sclera / Q000601:surgery*; D014792:Visual Acuity / Q000502:physiology
references.citation: Spec Rep Ser Med Res Counc (G B). 1957;11(293):1-69
references.pmid: 13399546
references.citation: Prog Retin Eye Res. 2005 Jan;24(1):1-38
references.pmid: 15555525
references.citation: Lancet. 2012 May 5;379(9827):1739-48
references.pmid: 22559900
references.citation: Oftalmol Zh. 1989;(4):204-7
references.pmid: 2797690
references.citation: Ann Acad Med Singap. 2004 Jan;33(1):27-33
references.pmid: 15008558
references.citation: Clin Exp Optom. 2003 Sep;86(5):273-5
references.pmid: 14558848
references.citation: Ophthalmic Physiol Opt. 2001 Nov;21(6):477-83
references.pmid: 11727876
references.citation: Am J Ophthalmol. 2008 Jul;146(1):102-110
references.pmid: 18455142
references.citation: Am J Ophthalmol. 1987 Apr 15;103(4):544-8
references.pmid: 3551619
references.citation: Clin Exp Ophthalmol. 2009 Sep;37(7):660-3
references.pmid: 19788661
references.citation: Invest Ophthalmol Vis Sci. 2009 Nov;50(11):5130-6
references.pmid: 19553618
references.citation: Invest Ophthalmol Vis Sci. 2000 Aug;41(9):2486-94
references.pmid: 10937558
references.citation: Ophthalmology. 1996 Aug;103(8):1241-4
references.pmid: 8764794
references.citation: Acta Ophthalmol Scand. 1997 Dec;75(6):618-23
references.pmid: 9527318
references.citation: Ophthalmic Surg. 1985 Feb;16(2):90-4
references.pmid: 4000627
references.citation: Optom Vis Sci. 2001 Apr;78(4):234-9
references.pmid: 11349931
references.citation: Eye (Lond). 2009 Dec;23(12):2169-74
references.pmid: 19229272
references.citation: Invest Ophthalmol Vis Sci. 2003 Nov;44(11):4630-8
references.pmid: 14578378
references.citation: Am J Ophthalmol. 1978 Dec;86(6):782-90
references.pmid: 736075
references.citation: Bratisl Lek Listy. 2001;102(2):73-8
references.pmid: 11396127
references.citation: Br J Ophthalmol. 1970 Jan;54(1):46-50
references.pmid: 5417654
references.citation: Ophthalmic Physiol Opt. 2005 Sep;25(5):381-91
references.pmid: 16101943
references.citation: Am J Ophthalmol. 1972 Aug;74(2):273-7
references.pmid: 5054236
references.citation: Br J Ophthalmol. 1976 Apr;60(4):271-2
references.pmid: 1276114
references.citation: J Biomed Mater Res. 1996 Oct;32(2):181-6
references.pmid: 8884493
references.citation: Ophthalmic Physiol Opt. 2012 Jan;32(1):3-16
references.pmid: 22150586
references.citation: J Biol Chem. 2003 May 9;278(19):16587-94
references.pmid: 12606541
references.citation: Arch Ophthalmol. 2009 Dec;127(12):1632-9
references.pmid: 20008719
references.citation: Invest Ophthalmol Vis Sci. 2004 Mar;45(3):793-9
references.pmid: 14985292
references.citation: Retina. 2012 Jun;32(6):1121-8
references.pmid: 22027863