title: Patients' perceptions of quality of life during active treatment for locally advanced rectal cancer: the importance of preoperative exercise.
abstract: OBJECTIVE
  The purpose of this longitudinal study was to explore advanced rectal cancer patients' perceptions of quality of life (QoL) during participation in a pre-surgery structured exercise program.
  
  
  METHODS
  Patients (n = 10) participated in repeated semi-structured in-depth interviews which covered four broad QoL domains (i.e., physical, psychological, social, and spiritual well-being). Patients' personal accounts of QoL were explored prior to (0 weeks), midway (3 weeks), and at completion (6 weeks) of the program. Data were analyzed using strategies grounded in a phenomenological approach.
  
  
  RESULTS
  Participation in the program facilitated positive changes in QoL over time by (1) fostering a greater sense of vitality, (2) cultivating a positive attitude, (3) enhancing social connections, and (4) fostering a strong sense of purpose in life for these patients.
  
  
  CONCLUSIONS
  Based on these data, preoperative exercise programs can be effective in promoting QoL among patients diagnosed and treated for locally advanced rectal cancer during a particularly difficult time in the cancer trajectory. Additional research is needed to develop and evaluate implementation strategies to facilitate the delivery of preoperative exercise programs as part of routine care in this population.
authors.affiliation: Centre for Sport and Exercise Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, LS29JT, UK, s.burke@leeds.ac.uk.
authors.forename: Shaunna M
authors.initials: SM
authors.lastname: Burke
authors.forename: Jennifer
authors.initials: J
authors.lastname: Brunet
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Sabiston
authors.forename: Sandy
authors.initials: S
authors.lastname: Jack
authors.forename: Michael P W
authors.initials: MP
authors.lastname: Grocott
authors.forename: Malcolm A
authors.initials: MA
authors.lastname: West
mesh_terms: D000368:Aged; D059186:Chemoradiotherapy, Adjuvant; D015444:Exercise / Q000523:psychology*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D010465:Perception; D011300:Preoperative Care / Q000379:methods / Q000523:psychology; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000473:pathology / Q000523:psychology* / Q000628:therapy*
references.citation: Psychooncology. 2007 Nov;16(11):980-4
references.pmid: 17351987
references.citation: Psychol Sci. 2012 Dec;23(12):1455-60
references.pmid: 23090755
references.citation: Qual Life Res. 2000 Mar;9(2):151-9
references.pmid: 10983479
references.citation: Cochrane Database Syst Rev. 2010 Jun 16;(6):CD005211
references.pmid: 20556760
references.citation: Cancer Pract. 2001 May-Jun;9(3):119-27
references.pmid: 11879296
references.citation: J Clin Oncol. 2006 Oct 1;24(28):4620-5
references.pmid: 17008704
references.citation: J Clin Oncol. 2011 Feb 1;29(4):406-12
references.pmid: 21172892
references.citation: J Natl Compr Canc Netw. 2012 Dec 1;10(12):1528-64
references.pmid: 23221790
references.citation: J Clin Oncol. 2005 Jun 1;23(16):3830-42
references.pmid: 15923576
references.citation: Cancer. 2007 Aug 1;110(3):590-8
references.pmid: 17582629
references.citation: CA Cancer J Clin. 1999 Jan-Feb;49(1):8-31, 1
references.pmid: 10200775
references.citation: Int J Palliat Nurs. 2010 Nov;16(11):536-41
references.pmid: 21135786
references.citation: J Consult Clin Psychol. 2008 Oct;76(5):863-75
references.pmid: 18837603
references.citation: Disabil Rehabil. 2013 May;35(9):732-9
references.pmid: 22897354
references.citation: J Pain Symptom Manage. 2012 Jan;43(1):96-110
references.pmid: 21640547
references.citation: CA Cancer J Clin. 2012 Jan-Feb;62(1):10-29
references.pmid: 22237781
references.citation: Am Psychol. 2000 Jun;55(6):647-54
references.pmid: 10892207
references.citation: Ann Surg. 2011 Jan;253(1):71-7
references.pmid: 21135694
references.citation: J Clin Oncol. 2012 Nov 1;30(31):3777-8
references.pmid: 23008292
references.citation: J Adv Nurs. 2004 Mar;45(5):512-8
references.pmid: 15009354
references.citation: Clin J Oncol Nurs. 2012 Jun 1;16(3):293-300
references.pmid: 22641322
references.citation: J Sport Exerc Psychol. 2007 Aug;29(4):419-38
references.pmid: 17968046
references.citation: Surg Endosc. 2013 Apr;27(4):1072-82
references.pmid: 23052535
references.citation: Oncology (Williston Park). 1997 Apr;11(4):565-8, 571; discussion 572, 575-6
references.pmid: 9130276
references.citation: West J Nurs Res. 1999 Dec;21(6):728-42
references.pmid: 11512210
references.citation: Am J Respir Crit Care Med. 2003 Jan 15;167(2):211-77
references.pmid: 12524257
references.citation: Arch Phys Med Rehabil. 2007 Nov;88(11):1416-22
references.pmid: 17964881
references.citation: Health Psychol. 1996 Mar;15(2):135-48
references.pmid: 8681922
references.citation: Ann Surg. 2011 Jul;254(1):97-102
references.pmid: 21494121
references.citation: J Clin Epidemiol. 2004 Jul;57(7):653-61
references.pmid: 15358393
references.citation: Cancer Epidemiol Biomarkers Prev. 2007 Dec;16(12):2572-8
references.pmid: 18086760
references.citation: Qual Life Res. 1995 Dec;4(6):523-31
references.pmid: 8556012
references.citation: Ann Behav Med. 1999 Spring;21(2):171-9
references.pmid: 10499138
references.citation: Eur J Cancer Care (Engl). 2004 Sep;13(4):362-70
references.pmid: 15305905
references.citation: Psychooncology. 2003 Jun;12(4):357-74
references.pmid: 12748973
references.citation: CMAJ. 2001 Aug 21;165(4):421-5
references.pmid: 11531050