title: Polarization sensitive optical low-coherence reflectometry for blood glucose monitoring in human subjects.
abstract: A device based on polarization sensitive optical low-coherence reflectometry is developed to monitor blood glucose levels in human subjects. The device was initially tested with tissue phantom. The measurements with human subjects for various glucose concentration levels are found to be linearly dependent on the ellipticity obtainable from the home-made phase-sensitive optical low-coherence reflectometry device. The linearity obtained between glucose concentration and ellipticity are explained with theoretical calculations using Mie theory. A comparison of results with standard clinical methods establishes the utility of the present device for non-invasive glucose monitoring.
authors.affiliation: Applied Photonics Laboratory, Department of Applied Physics, Shri G S Institute of Technology and Science, Indore 452 003, India.
authors.forename: Jitendra
authors.initials: J
authors.lastname: Solanki
authors.forename: Om Prakash
authors.initials: OP
authors.lastname: Choudhary
authors.forename: P
authors.initials: P
authors.lastname: Sen
authors.forename: J T
authors.initials: JT
authors.lastname: Andrews
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D006801:Humans; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D055096:Optical Devices; D055620:Optical Phenomena; D019047:Phantoms, Imaging; D012815:Signal Processing, Computer-Assisted
chemical_list: D001786:Blood Glucose