title: Vitamin D and psychosis: mini meta-analysis.
abstract: Individuals with psychotic disorders are more likely to have vitamin D (VD) deficiency, while evidence suggests VD could have pathophysiological roles. We summarized meta-analytically the available evidence on VD levels in psychotic disorders in comparison with healthy controls and other psychiatric illnesses. We found seven studies, all reporting insufficient VD levels in patients with psychosis. Schizophrenia had a medium effect size for lower VD than healthy controls, and a trend for lower levels than other psychoses. There were non-significant differences between schizophrenia and major depression. No study has investigated the potential psychotropic effects of VD supplementation in patients with psychosis.
authors.affiliation: Department of Neurosciences Division of Psychiatry, University of Parma, Parma, Italy; King's College London, Institute of Psychiatry, Department of Psychological Medicine, London, UK. Electronic address: martino.belvederi@gmail.com.
authors.forename: Martino
authors.initials: M
authors.lastname: Belvederi Murri
authors.forename: Matteo
authors.initials: M
authors.lastname: Respino
authors.forename: Mattia
authors.initials: M
authors.lastname: Masotti
authors.forename: Marco
authors.initials: M
authors.lastname: Innamorati
authors.forename: Valeria
authors.initials: V
authors.lastname: Mondelli
authors.forename: Carmine
authors.initials: C
authors.lastname: Pariante
authors.forename: Mario
authors.initials: M
authors.lastname: Amore
mesh_terms: D006801:Humans; D011618:Psychotic Disorders / Q000209:etiology*; D039781:PubMed / Q000706:statistics & numerical data; D014808:Vitamin D Deficiency / Q000150:complications*
keywords: Psychosis; Schizophrenia; Vitamin D