title: [The pharmacodynamic research on fuxiye, a Chinese herbal lotion for external wash].
abstract: OBJECTIVE
  To observe antisepsis, anti-swelling, and therapeutic effects of Fuxiye (FXY), a Chinese medical lotion for external wash in treating vaginitis model rats.
  
  
  METHODS
  The cervicitis rat model was induced by agar plate diffusion, ear auricle swelling induced by dimethylbenzene, and chemical stimulus. The in vitro antibiotic actions of FXY were observed. Besides, its effects on the swelling and inflammation in model rats were also observed.
  
  
  RESULTS
  FXY at 25 mg/mL could completely inhibit the growth of Pseudomonas aeruginosa, Escherichia coli, pyogenic Streptococcus, and Streptococcus agalactiae. FXY at 50 mg/mL could completely inhibit the growth of Staphylococcus aureus and Candida albicans. It obviously restrained dimethylbenzene induced ear auricle swelling. It significantly alleviated cervicitis induced by chemical stiumli.
  
  
  CONCLUSIONS
  FXY showed better effects on antisepsis, anti-inflammation, and treating cervicitis.
authors.affiliation: Zhejiang Provincial Administration of Traditional Chinese Medicine, Hangzhou 310006, China.
authors.forename: Xue-Qi
authors.initials: XQ
authors.lastname: Chen
authors.forename: Bei-Fen
authors.initials: BF
authors.lastname: Ge
authors.forename: Wei
authors.initials: W
authors.lastname: Shen
authors.forename: Pei
authors.initials: P
authors.lastname: Liu
authors.forename: Jun-Ming
authors.initials: JM
authors.lastname: Cao
authors.forename: Zhe
authors.initials: Z
authors.lastname: Chen
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000494:pharmacology*; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000494:pharmacology*; D004304:Dosage Forms; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D051381:Rats; D017207:Rats, Sprague-Dawley; D002575:Uterine Cervicitis / Q000188:drug therapy*; D014627:Vaginitis / Q000188:drug therapy
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D004304:Dosage Forms; D004365:Drugs, Chinese Herbal