title: [Soft tissue tumors of the head and neck region].
abstract: BACKGROUND
  The incidence of soft tissue tumors of the head and neck region is low: 300 and 3 in 100,000 for benign and malignant tumors, respectively. However, sarcomas particularly show a wide variety of different histological subtypes. This article provides an overview of the soft tissue tumors of the head and neck region treated in the authors' institution.
  
  
  METHODS
  This is a retrospective study including 106 patients treated between 2002 and 2010 due to a soft tissue tumor. Tumor- and patient-specific data were collected (benign/malignant tumor, location, TNM classification, therapy, R classification, grade).
  
  
  RESULTS
  In total, 77 benign tumors, 5 of intermediate benign/malignant nature and 24 sarcomas (with 7 different subtypes) were identified. Whereas the benign and intermediate tumors were treated by surgical removal, in 21 of the 24 sarcomas, treatment comprised a multimodal therapy regimen including radio- and/or chemotherapy.
  
  
  CONCLUSIONS
  Whereas benign tumors can be successfully treated by surgical resection, there is no uniform therapy regimen for sarcomas due to the variety of different histological subtypes. Only case-specific interdisciplinary disease management can offer good perspectives for therapeutic success.
authors.affiliation: Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde/Chirurgie, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Deutschland, Wiebke.Laffers@gmx.de.
authors.forename: W
authors.initials: W
authors.lastname: Laffers
authors.forename: G
authors.initials: G
authors.lastname: Stöhr
authors.forename: F
authors.initials: F
authors.lastname: Göke
authors.forename: E
authors.initials: E
authors.lastname: Wardelmann
authors.forename: S
authors.initials: S
authors.lastname: Keiner
authors.forename: M
authors.initials: M
authors.lastname: Zipfel
authors.forename: H
authors.initials: H
authors.lastname: Schüller
authors.forename: A O H
authors.initials: AO
authors.lastname: Gerstner
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D005858:Germany / Q000453:epidemiology; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult
references.citation: Cancer. 1994 Jul 15;74(2):697-702
references.pmid: 8033050
references.citation: Orthopade. 2010 Dec;39(12):1171-80
references.pmid: 21107807
references.citation: CA Cancer J Clin. 1987 Mar-Apr;37(2):66-76
references.pmid: 3102004
references.citation: HNO. 2012 Dec;60(12):1093-5
references.pmid: 23202866
references.citation: Int J Oral Maxillofac Surg. 2008 May;37(5):428-32
references.pmid: 18343096
references.citation: Head Neck. 2005 Sep;27(9):814-24
references.pmid: 16086411
references.citation: HNO. 2011 Apr;59(4):371-4
references.pmid: 21359585
references.citation: Ann Surg Oncol. 2004 Jun;11(6):619-28
references.pmid: 15172935
references.citation: Indian J Cancer. 2011 Jul-Sep;48(3):284-8
references.pmid: 21921324
references.citation: Laryngorhinootologie. 2004 Jul;83(7):433-7
references.pmid: 15257491
references.citation: Cancer. 2001 May 15;91(10):1914-26
references.pmid: 11346874
references.citation: Clin Sarcoma Res. 2012 Oct 04;2(1):14
references.pmid: 23036164
references.citation: Head Neck. 2007 May;29(5):439-45
references.pmid: 17163467
references.citation: Unfallchirurg. 1997 Dec;100(12):970-8
references.pmid: 9492644
references.citation: Cancer. 2000 Aug 15;89(4):868-72
references.pmid: 10951351
references.citation: Cancer. 2008 Aug 1;113(3):573-81
references.pmid: 18521899
references.citation: Head Neck. 2005 Oct;27(10):916-22
references.pmid: 16136585
references.citation: Ann Oncol. 2007 Oct;18(10):1716-21
references.pmid: 17660492
references.citation: Curr Oncol Rep. 2009 Mar;11(2):135-42
references.pmid: 19216845
references.citation: Eur J Cancer. 2008 Feb;44(3):432-40
references.pmid: 18077150
references.citation: Cancer Treat Rev. 2011 Oct;37(6):431-9
references.pmid: 21592670
references.citation: HNO. 2012 Nov;60(11):962-7
references.pmid: 23114542
references.citation: Eur J Surg Oncol. 2010 Jul;36(7):684-90
references.pmid: 20542404
references.citation: Oral Oncol. 2010 Nov;46(11):786-90
references.pmid: 20947413
references.citation: Crit Rev Oncol Hematol. 2007 Aug;63(2):111-24
references.pmid: 17555981
references.citation: HNO. 2012 Nov;60(11):957-61
references.pmid: 23114541
references.citation: Int J Radiat Oncol Biol Phys. 1997 Mar 15;37(5):975-84
references.pmid: 9169803
references.citation: Oral Oncol. 2004 Oct;40(9):890-7
references.pmid: 15380166
references.citation: Acta Otorrinolaringol Esp. 2011 Nov-Dec;62(6):436-42
references.pmid: 21820641
references.citation: Arch Otolaryngol Head Neck Surg. 1994 Sep;120(9):981-6
references.pmid: 8074826
references.citation: Oral Oncol. 2006 Aug;42(7):703-9
references.pmid: 16529978