title: Risk factors associated with asbestos-related diseases: a community-based case-control study.
abstract: BACKGROUND
  Asbestos is a first level carcinogen. However, few epidemiological studies analyse the risk and protective factors associated with asbestos-related diseases and follow up these conditions in the general population. Pleural mesothelioma, caused by inhalation of asbestos fibres at work, at home or in the environment, is the most representative asbestos-related disease.The objectives of this study are to analyse the risk and protective factors associated with asbestos-related diseases and to investigate the incidence of new clinical manifestations in patients already diagnosed with some form of ARD.
  
  
  METHODS
  We have designed a matched case-control study with follow up of both cohorts from a population of a health district of the Barcelona province that has been exposed to asbestos for a period of 90 years.
  
  
  CONCLUSIONS
  A better understanding of asbestos-related diseases should improve i) the clinical and epidemiological follow up of patients with this condition; ii) the design of new treatment strategies; iii) and the development of preventive activities. At the end of the study, the two cohorts created in this study (affected cases and healthy controls) will constitute the basis for future research.
authors.affiliation: Primary Care Team Serraparera, Catalan Institute of Health, Cerdanyola del Vallès, Spain. mrosell.mn.ics@gencat.cat.
authors.forename: Magdalena-Isabel
authors.initials: MI
authors.lastname: Rosell-Murphy
authors.forename: Rafael
authors.initials: R
authors.lastname: Abós-Herràndiz
authors.forename: Josep Tarrés
authors.initials: JT
authors.lastname: Olivella
authors.forename: Constança
authors.initials: C
authors.lastname: Alberti-Casas
authors.forename: Isabel García
authors.initials: IG
authors.lastname: Allas
authors.forename: Xavier Martinez
authors.initials: XM
authors.lastname: Artés
authors.forename: Ilona Krier
authors.initials: IK
authors.lastname: Günther
authors.forename: Isidre Grimau
authors.initials: IG
authors.lastname: Malet
authors.forename: Ramon Orriols
authors.initials: RO
authors.lastname: Martínez
authors.forename: Jaume
authors.initials: J
authors.lastname: Canela-Soler
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001194:Asbestos / Q000009:adverse effects; D001195:Asbestosis / Q000453:epidemiology* / Q000517:prevention & control; D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000517:prevention & control; D008297:Male; D008654:Mesothelioma / Q000453:epidemiology* / Q000517:prevention & control; D000086002:Mesothelioma, Malignant; D016273:Occupational Exposure / Q000706:statistics & numerical data; D012107:Research Design; D012111:Residence Characteristics; D012306:Risk; D012307:Risk Factors; D013030:Spain
chemical_list: D001194:Asbestos
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