title: Validity of colour doppler sonography for evaluation of portal venous system in hepatocellular carcinoma.
abstract: OBJECTIVE
  To assess the validity of colour doppler sonography in the evaluation of portal venous system in hepatocellular carcinoma.
  
  
  METHODS
  The study was conducted at the Department of Diagnostic and Interventional Radiology at Shifa International Hospital, Islamabad, from March to November 2009, and comprised 100 patients who were already diagnosed cases of hepatocellular carcinoma or those having high suspicion based on clinical criteria (e.g., chronic hepatitis B or C, liver cirrhosis, increased alpha fetoprotein level [>400ng/dl]) and/or Imaging findings (e.g., sonography, magnetic resonance imaging, computed tomography). Data was collected on pre-designed proforma and analysed on SPSS 10.
  
  
  RESULTS
  Portal vein thrombosis was found in 28 (28%) patients having hepatocellular carcinoma. Colour doppler sonography had 89.3% sensitivity and 95.8% specificity in the detection of portal vein thrombosis in comparison with biphasic computed tomography, which was taken as the gold standard.
  
  
  CONCLUSIONS
  Colour doppler sonognaphy is an effective, non-invasive method for evaluating the presence of portal vein thrombosis associated with hepatocellular carcinoma.
authors.affiliation: Radiology Department, Shifa International Hospital, Islamabad. Shahjehan135@yahoo.com
authors.forename: Shahjehan
authors.initials: S
authors.lastname: Alam
authors.forename: Rayyan
authors.initials: R
authors.lastname: Pervez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019540:Area Under Curve; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging*; D002648:Child; D003287:Contrast Media; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007479:Iopamidol; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011169:Portal Vein / Q000000981:diagnostic imaging*; D018615:Ultrasonography, Doppler, Color; D020246:Venous Thrombosis / Q000000981:diagnostic imaging*
chemical_list: D003287:Contrast Media; D007479:Iopamidol