title: [Characteristics of thyroid para-follicular cells in the offspring of female rats with chronic experimental liver injury at different stages of postnatal ontogenesis].
abstract: Structural and functional features of thyroid gland parafol-licular cell (PFC) population were studied the in 48 animals born to females with chronic experimental liver injury induced by injection of D-galactosamine hydrochloride. Using Grimelius silver nitrate impregnation method, PFC numbers were calculated and their subtypes according to their granular content and degranulation degree determined. Compared with the animals of the control group, the increase of PFC number per unit area together with the number of degranulated cells and the cells with a predominant location of granules on vascular pole was found. At the same time, the increase in the number of cells with moderate and significant degranulation was detected. The changes observed may be indicative of increased functional activity of PFC population in the experimental animals
authors.forename: D R
authors.initials: DR
authors.lastname: Soliannikova
authors.forename: G V
authors.initials: GV
authors.lastname: Briukhin
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development; D056487:Chemical and Drug Induced Liver Injury, Chronic / Q000473:pathology*; D005260:Female; D005688:Galactosamine / Q000633:toxicity; D006801:Humans; D008099:Liver / Q000473:pathology; D010298:Parity / Q000187:drug effects; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D013961:Thyroid Gland / Q000187:drug effects* / Q000254:growth & development / Q000473:pathology*
chemical_list: D005688:Galactosamine