title: Directing self-assembly of DNA nanotubes using programmable seeds.
abstract: Control over when and where nanostructures arise is essential for the self-assembly of dynamic or multicomponent devices. We design and construct a DNA origami seed for the control of DAE-E tile DNA nanotube assembly. Seeds greatly accelerate nanotube nucleation and growth because they serve as nanotube nucleation templates. Seeds also control nanotube circumference. Simulations predict nanotube growth rates and suggest a small nucleation barrier remains when nanotubes grow from seeds.
authors.affiliation: Chemical and Biomolecular Engineering and ‡Computer Science, Johns Hopkins University , Baltimore, Maryland 21218, United States.
authors.forename: Abdul M
authors.initials: AM
authors.lastname: Mohammed
authors.forename: Rebecca
authors.initials: R
authors.lastname: Schulman
mesh_terms: D004247:DNA / Q000138:chemical synthesis / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology; D043942:Nanotubes / Q000737:chemistry*; D009690:Nucleic Acid Conformation
chemical_list: D004247:DNA