title: Vocal fold paralysis in the presence of thyroid disease: management strategies.
abstract: BACKGROUND
  The presentation of vocal fold palsy with associated goitre has historically been considered to be due to malignancy with recurrent laryngeal nerve involvement.
  
  
  METHODS
  In total, 830 consecutive patients who underwent thyroid surgery were reviewed. Patients with vocal fold paralysis and thyroid disease were examined to determine the aetiology of the paralysis.
  
  
  RESULTS
  Nine patients were identified with new onset vocal fold paralysis prior to thyroid surgery. Six of the patients with recurrent laryngeal nerve paralysis had benign thyroid disease, and for three of the patients the paralysis was secondary to malignancy.
  
  
  CONCLUSIONS
  Recurrent laryngeal nerve paralysis in the presence of thyroid disease is not pathognomonic for malignancy. The current literature may underestimate the association between vocal fold paralysis and benign thyroid disease. The paper also highlights the importance of recurrent laryngeal nerve preservation in patients who present with palsy and thyroid disease; the relief of benign compression often leads to complete recovery of recurrent laryngeal nerve paralysis.
authors.affiliation: Department of Otolaryngology Head And Neck Surgery, Royal Victoria Eye and Ear Hospital, Dublin, Ireland. fergaloduffy@hotmail.com
authors.forename: F
authors.initials: F
authors.lastname: O'Duffy
authors.forename: C
authors.initials: C
authors.lastname: Timon
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012009:Recurrent Laryngeal Nerve / Q000601:surgery; D012189:Retrospective Studies; D013959:Thyroid Diseases / Q000150:complications* / Q000601:surgery; D013964:Thyroid Neoplasms / Q000150:complications; D013965:Thyroidectomy; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000209:etiology* / Q000601:surgery* / Q000628:therapy