title: [Cutaneous pemphigus vulgaris. A case report].
abstract: Pemphigus is an autoimmune bullous disease that involves skin and mucous membranes caused by autoantibodies against antigens on the surface of keratinocytes. We report a 30-year-old mole presenting with a five months history of pruriginous alopecic and crusted lesions in the scalp, that extended posteriorly to the trunk and limbs. Mucous membranes were not involved. A skin biopsy was performed, showing extensive loss of epidermis and acantholysis. Immuno fluorescence was positive for C3 and intercellular and epidermic IgG. With the presumptive diagnosis of pemphigus vulgaris (PV) without mucous involvement, the patient was treated with prednisone, observing an excellent clinical response. There are only few cases published in the literature of PV without mucous involvement. Some authors refer to this subtype of PV as "Cutaneous pemphigus vulgaris".
authors.affiliation: Departamento de Dermatología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Chile. cbello@med.puc.el
authors.forename: Cristina
authors.initials: C
authors.lastname: Bello
authors.forename: Luis
authors.initials: L
authors.lastname: Mondaca-Cornejo
authors.forename: Cristian
authors.initials: C
authors.lastname: Navarrete-Dechent
authors.forename: Sergio
authors.initials: S
authors.lastname: González
mesh_terms: D000328:Adult; D001706:Biopsy; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010392:Pemphigus / Q000188:drug therapy / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D012536:Scalp Dermatoses / Q000188:drug therapy / Q000473:pathology
chemical_list: D005938:Glucocorticoids; D011241:Prednisone