title: Synthesis of ZnO nanoparticles and evaluation of antioxidant and cytotoxic activity.
abstract: ZnO nanoparticles were synthesized by thermal decomposition method and were characterized by UV-vis spectroscopy, XRD, SEM, EDX and TEM analysis. The resultant nanoparticles are nearly spherical and size is in the range of 40-50 nm. The antioxidant behavior of ZnO nanoparticles was assessed by scavenging free radicals of 2,2-diphenyl-1-picrylhydrazyl hydrate (DPPH) with varying nanoparticle concentration and time interval individually. The DPPH scavenging activity was monitored by UV-vis spectrophotometer. ZnO nanoparticles were also showing cytotoxic activity which was studied by hemolytic potentiality test.
authors.affiliation: Department of Chemical Sciences, India.
authors.forename: Dhaneswar
authors.initials: D
authors.lastname: Das
authors.affiliation: Department of Physics, India.
authors.forename: Bikash Chandra
authors.initials: BC
authors.lastname: Nath
authors.affiliation: Department of Molecular Biology and Biotechnology, Tezpur University, Napaam, Assam, India.
authors.forename: Pinkee
authors.initials: P
authors.lastname: Phukon
authors.affiliation: Department of Chemical Sciences, India.
authors.forename: Amarjyoti
authors.initials: A
authors.lastname: Kalita
authors.affiliation: Department of Chemical Sciences, India. Electronic address: dolui@tezu.ernet.in.
authors.forename: Swapan Kumar
authors.initials: SK
authors.lastname: Dolui
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D016923:Cell Death / Q000187:drug effects; D006461:Hemolysis / Q000187:drug effects; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D012756:Sheep; D013052:Spectrometry, X-Ray Emission; D013056:Spectrophotometry, Ultraviolet; D013997:Time Factors; D014961:X-Ray Diffraction; D015034:Zinc Oxide / Q000138:chemical synthesis* / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D015034:Zinc Oxide
keywords: Antioxidant; Cytotoxic; DPPH; Nanoparticle; ZnO