title: Prospective cohort study comparing seasonal and H1N1(2009) pandemic influenza virus illnesses in HIV-infected children during 2009.
abstract: A cohort of 410 young HIV-infected children was prospectively investigated for seasonal and A(H1N1p)2009 influenza virus illness during 2009. The incidence of confirmed illness due to seasonal influenza was 3-fold greater than A(H1N1p)2009 (0.7 vs. 0.2 per 100 child-weeks, respectively; P = 0.0001), and the clinical presentations were similar. Illnesses due to seasonal and A(H1N1p)2009 influenza were self-limiting without neuraminidase inhibitor therapy.
authors.affiliation: From the *National Institute of Communicable Diseases-Division of National Health Laboratory Service; †Department of Science and Technology/National Research Foundation: Vaccine Preventable Diseases; ‡Medical Research Council: Respiratory and Meningeal Pathogens Research Unit; and §Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: Shabir A
authors.initials: SA
authors.lastname: Madhi
authors.forename: Locadiah
authors.initials: L
authors.lastname: Kuwanda
authors.forename: Marietjie
authors.initials: M
authors.lastname: Venter
authors.forename: Avy
authors.initials: A
authors.lastname: Violari
mesh_terms: D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006678:HIV; D015658:HIV Infections / Q000453:epidemiology* / Q000821:virology*; D006801:Humans; D015994:Incidence; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype; D007252:Influenza Vaccines / Q000008:administration & dosage; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control / Q000821:virology*; D008297:Male; D058873:Pandemics / Q000706:statistics & numerical data; D011446:Prospective Studies; D013019:South Africa / Q000453:epidemiology
chemical_list: D007252:Influenza Vaccines