title: Experimental validation of the fluid-structure interaction simulation of a bioprosthetic aortic heart valve.
abstract: Experiments performed on a 19 mm diameter bioprosthetic valve were used to successfully validate the fluid-structure interaction (FSI) simulation of an aortic valve at 72 bpm. The FSI simulation was initialized via a novel approach utilizing a Doppler sonogram of the experimentally tested valve. Using this approach very close quantitative agreement (≤12.5%) between the numerical predictions and experimental values for several key valve performance parameters, including the peak systolic transvalvular pressure gradient, rapid valve opening time and rapid valve closing time, was obtained. The predicted valve leaflet kinematics during opening and closing were also in good agreement with the experimental measurements.
authors.affiliation: Department of Mechanical and Mechatronic Engineering, Stellenbosch University, Private Bag X1, Matieland, Stellenbosch, Western Cape Province 7602, South Africa.
authors.forename: I
authors.initials: I
authors.lastname: Kemp
authors.forename: K
authors.initials: K
authors.lastname: Dellimore
authors.forename: R
authors.initials: R
authors.lastname: Rodriguez
authors.forename: C
authors.initials: C
authors.lastname: Scheffer
authors.forename: D
authors.initials: D
authors.lastname: Blaine
authors.forename: H
authors.initials: H
authors.lastname: Weich
authors.forename: A
authors.initials: A
authors.lastname: Doubell
mesh_terms: D001021:Aortic Valve / Q000502:physiology* / Q000601:surgery*; D032701:Biomimetics / Q000295:instrumentation; D001705:Bioprosthesis; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D003198:Computer Simulation; D017076:Computer-Aided Design; D019544:Equipment Failure Analysis; D006350:Heart Valve Prosthesis; D006801:Humans; D008955:Models, Cardiovascular; D011474:Prosthesis Design; D012212:Rheology / Q000295:instrumentation* / Q000379:methods*