title: [Antiproliferative effect of polar lipids of maral antlers and peat in prostate benign hyperplasia model].
abstract: Lipids isolated from maral antlers and peat decreased the prostate posterior and lateral lobule mass and normalized its acinar and stromal histological structure, reduced protein content, decreased formation of lipid peroxidation products, and intensified antioxidant protection in homogenates, decreased prolactine and 5a-dihydrotestosterone blood level, and increased testosterone blood content in male rats of late reproductive age with prostate benign hyperplasia model caused by sulpiride injections. Polar lipids of maral antlers and peat more effectively suppress prostate hyperplasia and hyperprolactinemia development in comparison to the action of Serenoa repens extract (permixon).
authors.forename: A I
authors.initials: AI
authors.lastname: Vengerovskiĭ
authors.forename: V N
authors.initials: VN
authors.lastname: Burkova
authors.forename: N V
authors.initials: NV
authors.lastname: Iudina
authors.forename: A I
authors.initials: AI
authors.lastname: Iatsenkov
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D000999:Antlers / Q000737:chemistry*; D049109:Cell Proliferation / Q000187:drug effects*; D045424:Complex Mixtures / Q000737:chemistry / Q000494:pharmacology*; D003670:Deer; D004195:Disease Models, Animal; D015227:Lipid Peroxidation / Q000187:drug effects; D008055:Lipids / Q000737:chemistry / Q000494:pharmacology*; D008297:Male; D051379:Mice; D011470:Prostatic Hyperplasia / Q000097:blood / Q000188:drug therapy*; D013739:Testosterone / Q000097:blood
chemical_list: D000975:Antioxidants; D045424:Complex Mixtures; D008055:Lipids; D013739:Testosterone