title: Effects of different irrigation solutions on root dentine microhardness, smear layer removal and erosion.
abstract: This study aimed to compare the effects of different irrigants on root dentine microhardness, erosion and smear layer removal. A total of 72 root dentine slices were divided into six groups, according to the final irrigants used: Group 1: 17% ethylenediamine tetra-acetic acid (EDTA) + 2.5% NaOCl, Group 2: 7% maleic acid (MA) + 2.5% sodium hypochloride (NaOCl), Group 3: 1.3% NaOCl + mixture of tetracycline, acid and detergent (MTAD), Group 4: Smear Clear + 2.5% NaOCl, Group 5: 5% NaOCl, Group 6: saline. Vickers microhardness values were measured before and after treatment. In total, 42 root-halves were prepared for scanning electron microscope to evaluate the amount of smear and erosion in the coronal, middle and apical thirds. Data were analysed using two-way anova, Duncan and two-proportion z-tests. Maleic acid showed the greatest reduction in dentine microhardness (P < 0.05), followed by EDTA and MTAD. EDTA, maleic acid, MTAD and Smear Clear removed smear layer efficiently in the coronal and middle thirds of root canal. However, in the apical region, maleic acid showed more efficient removal of the smear layer than the other irrigants (P < 0.05).
authors.affiliation: Gazi University, Faculty of Dentistry, Department of Restorative Dentistry and Endodontics, Ankara, Turkey. ilkeatasoy@yahoo.com
authors.forename: Özgür İ A
authors.initials: Öİ
authors.lastname: Ulusoy
authors.forename: Güliz
authors.initials: G
authors.lastname: Görgül
mesh_terms: D019343:Citric Acid / Q000494:pharmacology; D003786:Dental Pulp Cavity / Q000187:drug effects* / Q000648:ultrastructure; D003804:Dentin / Q000187:drug effects* / Q000648:ultrastructure; D004318:Doxycycline / Q000494:pharmacology; D004338:Drug Combinations; D004492:Edetic Acid / Q000494:pharmacology; D006244:Hardness; D006801:Humans; D008298:Maleates / Q000494:pharmacology; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D011136:Polysorbates / Q000494:pharmacology; D012388:Root Canal Irrigants / Q000494:pharmacology*; D016369:Smear Layer; D012965:Sodium Chloride; D012973:Sodium Hypochlorite / Q000494:pharmacology; D019227:Tooth Apex / Q000187:drug effects / Q000648:ultrastructure; D014077:Tooth Erosion / Q000139:chemically induced / Q000473:pathology
chemical_list: D004338:Drug Combinations; C475043:MTAD (intracanal irrigant); D008298:Maleates; D011136:Polysorbates; D012388:Root Canal Irrigants; C521331:Smear Clear; D019343:Citric Acid; D012965:Sodium Chloride; C030272:maleic acid; D004492:Edetic Acid; D012973:Sodium Hypochlorite; D004318:Doxycycline
keywords: irrigation; maleic acid; microhardness; root canal; smear layer