title: Conjunctival lymphoma: immunophenotype and outcome in five dogs and three cats.
abstract: Conjunctival lymphoma is well documented in the medical literature, but veterinary reports are few. We report five cases of canine lymphoma, and three of feline in which the presenting sign was conjunctival involvement. All animals were in apparently good health at the time of presentation, and attended the referring clinic because of conjunctival disease. One dog showed generalized lymphadenopathy at presentation, although the ocular lesion was the reason for consultation, but all other patients were well with no detectable disease beyond the eye. All cats were presented for their ocular disease. All dogs were confirmed to have T-cell tumors, although the histological appearance of these was variable. In contrast, all cats had B-cell tumors. Referring clinicians and owners were contacted for follow-up information. Three dogs had been euthanased within 6 months of diagnosis for deterioration of general health. The remaining two were alive and showed no signs of systemic disease. Two cats had good survival following diagnosis, the other died of lesions that may not be related.
authors.affiliation: University of Melbourne Veterinary Clinical Centre, 250 Princes Hwy, Werribee, Melbourne, 3030, Vic., Australia; Veterinary Diagnostics, Biosciences Research Division, Department of Primary Industries, 5 Ring Road, Bundoora, Melbourne, 308, Vic., Australia.
authors.forename: Christina
authors.initials: C
authors.lastname: McCowan
authors.forename: Julia
authors.initials: J
authors.lastname: Malcolm
authors.forename: Simon
authors.initials: S
authors.lastname: Hurn
authors.forename: Anu
authors.initials: A
authors.lastname: O'Reilly
authors.forename: Chloe
authors.initials: C
authors.lastname: Hardman
authors.forename: Robin
authors.initials: R
authors.lastname: Stanley
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D002415:Cats; D003230:Conjunctival Neoplasms / Q000175:diagnosis / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D004285:Dogs; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D008223:Lymphoma / Q000175:diagnosis / Q000662:veterinary*; D008297:Male
keywords: canine; conjunctiva; feline; immunohistochemistry; lymphoma; outcome