title: Renal artery fibromuscular dysplasia in 2,640 renal donor subjects: a CT angiography analysis.
abstract: OBJECTIVE
  To present the incidence, demographics, and clinical presentation of patients diagnosed with renal fibromuscular dysplasia (FMD) who underwent computed tomography (CT) angiography for evaluation of living renal donor protocol.
  
  
  METHODS
  A retrospective review was performed from January 1, 2000, to December 31, 2011 on patients who underwent CT angiography for evaluation of living renal donor protocol. Of 2,640 patients identified, only patients with a diagnosis of FMD by the radiology report underwent independent reader evaluation of CT angiography for the presence of FMD and associated characteristics. The demographics, medical history, and presentation were reviewed using the electronic medical chart.
  
  
  RESULTS
  The independent readers who evaluated CT angiography identified a diagnosis of FMD in 68 patients (2.6%; 59 female) with an average age of 52 years ± 10. Unilateral FMD was observed in 46 patients (68%), and bilateral FMD was observed in 22 patients (32%). Three patients had aneurysms of the renal artery. Comorbidities included hypertension (n = 21, 31%), dyslipidemia, (n = 13, 19%), history of migraines (n = 3, 4%), and history of smoking (n = 14, 21%). No patients had diabetes mellitus, coronary artery disease, or family history of FMD. Of 21 patients (31%) with a history of hypertension, 13 patients (62%) were treated with antihypertensive medications.
  
  
  CONCLUSIONS
  The incidence of FMD in patients who underwent CT angiography for evaluation of living renal donor protocol is 2.6%.
authors.affiliation: Department of Vascular and Interventional Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905.
authors.forename: Gavin A
authors.initials: GA
authors.lastname: McKenzie
authors.forename: Gustavo S
authors.initials: GS
authors.lastname: Oderich
authors.forename: Akira
authors.initials: A
authors.lastname: Kawashima
authors.forename: Sanjay
authors.initials: S
authors.lastname: Misra
mesh_terms: D017677:Age Distribution; D000792:Angiography / Q000706:statistics & numerical data*; D015897:Comorbidity; D005260:Female; D005352:Fibromuscular Dysplasia / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D016030:Kidney Transplantation / Q000706:statistics & numerical data*; D019520:Living Donors / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D008910:Minnesota / Q000453:epidemiology; D011183:Postoperative Complications / Q000000981:diagnostic imaging* / Q000453:epidemiology; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012307:Risk Factors; D012680:Sensitivity and Specificity; D017678:Sex Distribution; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data*; D016896:Treatment Outcome
keywords: DSA; FMD; digital subtraction angiography; fibromuscular dysplasia
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