title: Lethal fetal stroke in utero.
abstract: OBJECTIVE
  Fetal intracranial hemorrhage (ICH) in utero is a rare complication of pregnancy associated with subsequent neurological sequelae or fetal death.
  
  
  METHODS
  A 34-year-old woman with Crohn's disease presented at 36 weeks' gestation due to decreased fetal movement. Fetal heart-rate tracing indicated poor beat-to-beat variability. In addition, a Doppler ultrasonography suggested a prenatal stroke with evidences of ICH, reverse-end diastolic velocity of the middle cerebral artery, and a persistent distended bladder. A nonaggressive treatment option was chosen after counseling about the unfavorable prognosis. However, 22 hours after her admission, intrauterine fetal death occurred.
  
  
  CONCLUSIONS
  Fetal ICH in utero might be a rare yet lethal complication of Crohn's disease in pregnancy.
authors.affiliation: Dianthus Maternal Fetal Medicine Clinic, Taipei City, Taiwan.
authors.forename: Tzu-Hung
authors.initials: TH
authors.lastname: Lin
authors.forename: Chien-Nan
authors.initials: CN
authors.lastname: Lee
authors.forename: Yi-Ning
authors.initials: YN
authors.lastname: Su
mesh_terms: D000328:Adult; D003424:Crohn Disease; D017809:Fatal Outcome; D005260:Female; D005313:Fetal Death; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D020300:Intracranial Hemorrhages / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011248:Pregnancy Complications / Q000000981:diagnostic imaging / Q000473:pathology; D020521:Stroke / Q000000981:diagnostic imaging* / Q000473:pathology*; D016216:Ultrasonography, Prenatal
keywords: Crohn's disease; fetal cerebral hemorrhage; fetal intracranial hemorrhage; fetal intraventricular hemorrhage; fetal stroke