title: REM sleep phase preference in the crepuscular Octodon degus assessed by selective REM sleep deprivation.
abstract: OBJECTIVE
  To determine rapid eye movement (REM) sleep phase preference in a crepuscular mammal (Octodon degus) by challenging the specific REM sleep homeostatic response during the diurnal and nocturnal anticrepuscular rest phases.
  
  
  METHODS
  We have investigated REM sleep rebound, recovery, and documented REM sleep propensity measures during and after diurnal and nocturnal selective REM sleep deprivations.
  
  
  METHODS
  Nine male wild-captured O. degus prepared for polysomnographic recordings.
  
  
  METHODS
  Animals were recorded during four consecutive baseline and two separate diurnal or nocturnal deprivation days, under a 12:12 light-dark schedule. Three-h selective REM sleep deprivations were performed, starting at midday (zeitgeber time 6) or midnight (zeitgeber time 18).
  
  
  RESULTS
  Diurnal and nocturnal REM sleep deprivations provoked equivalent amounts of REM sleep debt, but a consistent REM sleep rebound was found only after nocturnal deprivation. The nocturnal rebound was characterized by a complete recovery of REM sleep associated with an augment in REM/total sleep time ratio and enhancement in REM sleep episode consolidation.
  
  
  CONCLUSIONS
  Our results support the notion that the circadian system actively promotes REM sleep. We propose that the sleep-wake cycle of O. degus is modulated by a chorus of circadian oscillators with a bimodal crepuscular modulation of arousal and a unimodal promotion of nocturnal REM sleep
authors.affiliation: Programa de Fisiología y Biofísica, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile. neuro@gmail.com
authors.forename: Adrián
authors.initials: A
authors.lastname: Ocampo-Garcés
authors.forename: Felipe
authors.initials: F
authors.lastname: Hernández
authors.forename: Adrian G
authors.initials: AG
authors.lastname: Palacios
mesh_terms: D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology; D008297:Male; D046329:Octodon / Q000502:physiology*; D017286:Polysomnography; D012892:Sleep Deprivation / Q000503:physiopathology*; D012895:Sleep, REM / Q000502:physiology*; D013997:Time Factors
keywords: Octodon degus; REM sleep; REM sleep homeostasis; REM sleep rebound; crepuscular chronotype
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