title: [4+3] Cycloaddition of in situ generated azoalkenes with C,N-cyclic azomethine imines: efficient synthesis of tetrazepine derivatives.
abstract: An unprecedented [4+3] cycloaddition of in situ generated azoalkenes with C,N-cyclic azomethine imines has been developed without the use of any catalyst, providing an efficient and mild approach to synthesise highly functionalized 1,2,4,5-tetrazepine derivatives in high yields (76-92%).
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China.
authors.forename: Xiao-Qiang
authors.initials: XQ
authors.lastname: Hu
authors.forename: Jia-Rong
authors.initials: JR
authors.lastname: Chen
authors.forename: Shuang
authors.initials: S
authors.lastname: Gao
authors.forename: Bin
authors.initials: B
authors.lastname: Feng
authors.forename: Liang-Qiu
authors.initials: LQ
authors.lastname: Lu
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: Xiao
mesh_terms: D001381:Azepines / Q000138:chemical synthesis / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry*; D018360:Crystallography, X-Ray; D061565:Cycloaddition Reaction; D007097:Imines / Q000737:chemistry*; D015394:Molecular Structure; D013882:Thiosemicarbazones / Q000737:chemistry*
chemical_list: D001381:Azepines; D001391:Azo Compounds; D007097:Imines; D013882:Thiosemicarbazones; C512188:azomethine