title: [Trans fatty acids in the nutrition of children with neurological disorders].
abstract: BACKGROUND
  Trans-fatty acids are present in various foods, being the only source of the same in humans. Its presence in high concentrations is a risk factor for health, being involved in a series of events, cardiovascular, inflammatory, etc. Therefore, steps have been taken for its decrease in the diet. The aim is to determine serum and phospholipids of membranes in healthy children and neurological alterations.
  
  
  METHODS
  It has analyzed the fatty acids trans in 34 healthy children and 374 with various neurological pathologies. Serum and blood cells, making the lipid extraction, samples have been separation of the phospholipids of cells membranes, methylation of fatty acids, separation by gas chromatography and quantification using mass detector. The data have been processed statistically.
  
  
  RESULTS
  The distribution of trans fatty acids and their sum is not normally distributed, so its nonparemetric tests were used. The values are higher than in serum phospholipids and membrane with a weak but significant correlation. The tC18: 1 is in a double proportion in children with neurological disorders in healthy children, both in serum and membrane phospholipids, with significant differences.
  
  
  CONCLUSIONS
  The highest proportion of trans-fatty acids in the group of children with neurological disorders is caused no doubt by an increase in intake, due to less adequate food.
authors.affiliation: Universidad Miguel Hernández, España.
authors.forename: E
authors.initials: E
authors.lastname: Cortés
authors.forename: M J
authors.initials: MJ
authors.lastname: Aguilar
authors.forename: M M
authors.initials: MM
authors.lastname: Rizo
authors.forename: M J
authors.initials: MJ
authors.lastname: Hidalgo
mesh_terms: D002462:Cell Membrane / Q000737:chemistry; D002648:Child; D004032:Diet; D005260:Female; D005504:Food Analysis; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008297:Male; D008745:Methylation; D009422:Nervous System Diseases / Q000378:metabolism*; D009752:Nutritional Status; D010743:Phospholipids / Q000032:analysis*; D044242:Trans Fatty Acids / Q000032:analysis*
chemical_list: D010743:Phospholipids; D044242:Trans Fatty Acids