title: Kidney involvement in a Wegener granulomatosis case.
abstract: Wegener Granulomatosis is a systemic Anti-Neutrophil Cytoplasmic Autoantibody-associated Vasculitis, affecting small-to-medium vessels. Clinical presentation with simultaneous involvement of kidney and upper and lower respiratory tract is unusual. We report an instructive case of WG, analyzing clinical course, laboratory, and radiological features, kidney, lung, and larynx histological pictures. Besides renal biopsy, nephrology team performed larynx and lung biopsies because of unusual clinical presentation, computed tomography chest examination, and relevant malignancy risk regarding following immunosuppressant therapy.
authors.affiliation: Department of Nephrology and Dialysis, Civic and Di Cristina Hospital, Palermo, Sicily, Italy. gioacchinolicavoli@libero.it
authors.forename: Gioacchino Li
authors.initials: GL
authors.lastname: Cavoli
authors.forename: Angelo
authors.initials: A
authors.lastname: Ferrantelli
authors.forename: Luisa
authors.initials: L
authors.lastname: Bono
authors.forename: Calogera
authors.initials: C
authors.lastname: Tortorici
authors.forename: Rita
authors.initials: R
authors.lastname: Passantino
authors.forename: Ugo
authors.initials: U
authors.lastname: Rotolo
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007818:Laryngeal Diseases / Q000209:etiology* / Q000473:pathology; D008171:Lung Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011859:Radiography; D051437:Renal Insufficiency / Q000209:etiology* / Q000473:pathology
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic