title: Lewis base catalyzed synthesis of multisubstituted 4-sulfonyl-1H-pyrazole involving a novel 1,3-sulfonyl shift.
abstract: A facile synthesis of highly substituted 4-sulfonyl-1H-pyrazoles from N-propargylic sulfonylhydrazone derivatives has been developed. Allenic sulfonamide formation and 1,3-sulfonyl shift were established to be the critical steps of this transformation.
authors.affiliation: Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, Fujian, P. R. China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhu
authors.forename: Wen-Ting
authors.initials: WT
authors.lastname: Lu
authors.forename: Hong-Chao
authors.initials: HC
authors.lastname: Sun
authors.forename: Zhuang-Ping
authors.initials: ZP
authors.lastname: Zhan
mesh_terms: D002384:Catalysis; D006835:Hydrazones / Q000737:chemistry*; D058115:Lewis Bases / Q000737:chemistry*; D015394:Molecular Structure; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: C585709:4-sulfonyl-1H-pyrazole; D006835:Hydrazones; D058115:Lewis Bases; C585708:N-propargylic sulfonylhydrazone; D011720:Pyrazoles; C031280:pyrazole