title: Increased red cell distribution width level is associated with absence of coronary collateral vessels in patients with acute coronary syndromes.
abstract: OBJECTIVE
  Several studies have evaluated a relationship between increased red cell distribution width (RDW) and morbidity and mortality of acute coronary syndrome (ACS). In this study, we aimed to investigate the association of serum RDW levels and development of coronary collateral vessel (CCV) in patients with ACS.
  
  
  METHODS
  We evaluated 226 patients with ACS in this prospective and cross-sectional study. Traditional laboratory and clinical parameters and serum RDW levels were measured on admission. All patients underwent coronary angiography on the first day after admission and patients with >80% stenosis were included in the study. The CCV was graded according to the Rentrop scoring system, and a Rentrop grade 0 was accepted as no CCV development (Group 1), while Rentrop grades 1-2-3 were accepted as presence of CCV development (Group 2).
  
  
  RESULTS
  Only levels of RDW were significantly higher in Group 1 than in Group 2 (Group 1 RDW 14.6±1.9, Group 2 RDW 14.1±1.4, p=0.02). The predictive value of serum RDW level for absence of collaterals (sensitivity of 58% and specificity of 54%, area under the receiver operating characteristic (ROC) curve = 0.573) was 13.90.
  
  
  CONCLUSIONS
  We found that high levels of RDW were associated with absence of CCV in patients with ACS.
authors.affiliation: Department of Cardiology, Kayseri Training and Research Hospital, Kayseri, Turkey. mduran2@gmail.com
authors.forename: Mustafa
authors.initials: M
authors.lastname: Duran
authors.forename: Onur Kadir
authors.initials: OK
authors.lastname: Uysal
authors.forename: Ozgür
authors.initials: O
authors.lastname: Günebakmaz
authors.forename: Yücel
authors.initials: Y
authors.lastname: Yılmaz
authors.forename: Fatih
authors.initials: F
authors.lastname: Akın
authors.forename: Oğuzhan
authors.initials: O
authors.lastname: Baran
authors.forename: Mehmet Tuğrul
authors.initials: MT
authors.lastname: Inanç
authors.forename: Namık Kemal
authors.initials: NK
authors.lastname: Eryol
authors.forename: Ali
authors.initials: A
authors.lastname: Ergin
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Oğuzhan
authors.forename: Mehmet Güngör
authors.initials: MG
authors.lastname: Kaya
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000000981:diagnostic imaging; D001810:Blood Volume; D003097:Collateral Circulation; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D004909:Erythrocyte Indices; D004912:Erythrocytes; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012372:ROC Curve