title: Photoinduced cell morphology alterations quantified within adipose tissues by spectral optical coherence tomography.
abstract: Morphological changes of the adipose tissue at phototreatment are studied in vitro using optical coherence tomography. The 200 to 600 μm fat tissue slices are used in the experiments. The observed change in the tissue structure was associated with fat cell lipolysis and destruction caused by the photodynamic effect. It is found that overall heating of a sample from room to physiological temperature leads to deeper and faster morphology tissue changes if other processing conditions are kept constant. These data support the hypothesis that photodynamic/photothermal treatment induces fat cell lipolysis during some period after treatment.
authors.affiliation: Saratov State University, Research-Educational Institute of Optics and Biophotonics, 83 Astrakhanskaya Street, Saratov 410012, Russia. irina-yanina@list.ru
authors.forename: Irina Yu
authors.initials: IY
authors.lastname: Yanina
authors.forename: Natalia A
authors.initials: NA
authors.lastname: Trunina
authors.forename: Valery V
authors.initials: VV
authors.lastname: Tuchin
mesh_terms: D000273:Adipose Tissue / Q000166:cytology* / Q000528:radiation effects*; D000465:Algorithms; D048429:Cell Size / Q000528:radiation effects; D006652:Histological Techniques; D007259:Infrared Rays; D008066:Lipolysis / Q000528:radiation effects*; D013696:Temperature; D041623:Tomography, Optical Coherence / Q000379:methods*