title: Tonsillar Kaposi sarcoma in a patient with membranous glomerulonephritis on immunosuppressive therapy.
abstract: Kaposi sarcoma is a malignant vascular neoplasm uncommonly seen in immunosuppressed patients. Herein we report an unusual case of tonsillar Kaposi sarcoma in a patient with membranous glomerulonephritis treated with prednisolone and cyclosporine. The patient presented after 10 months of starting the treatment with a tonsillar mass. Histological examination was typical of monomorphic spindle cell proliferation with slit-like vascular channels. The tumor cells expressed CD34, D2-40 and positive nuclear stain for HHV-8. Kaposi sarcoma is associated with immunosuppression and rarely occurs in the tonsil. Clinicians should be aware of this rare presentation of Kaposi sarcoma.
authors.affiliation: Department of Pathology, Farwaniya Hospital, Salmiya, Kuwait 22034. nabeel.albrahim@gmail.com
authors.forename: Nabeel
authors.initials: N
authors.lastname: Al-Brahim
authors.forename: Ashraf H
authors.initials: AH
authors.lastname: Zaki
authors.forename: Khaled
authors.initials: K
authors.lastname: El-Merhi
authors.forename: Mahmoud S
authors.initials: MS
authors.lastname: Ahmad
mesh_terms: D000328:Adult; D016572:Cyclosporine / Q000627:therapeutic use; D015433:Glomerulonephritis, Membranous / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D012514:Sarcoma, Kaposi / Q000175:diagnosis*; D014067:Tonsillar Neoplasms / Q000175:diagnosis*
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011239:Prednisolone