title: Emerging roles for RNA polymerase II CTD in Arabidopsis.
abstract: Post-translational modifications of the carboxy-terminal domain of the largest subunit of RNA polymerase II (RNAPII CTD) provide recognition marks to coordinate recruitment of numerous nuclear factors controlling transcription, cotranscriptional RNA processing, chromatin remodeling, and RNA export. Compared with the progress in yeast and mammals, deciphering the regulatory roles of position-specific combinatorial CTD modifications, the so-called CTD code, is still at an early stage in plants. In this review, we discuss some of the recent advances in understanding of the molecular mechanisms controlling the deposition and recognition of RNAPII CTD marks in plants during the transcriptional cycle and highlight some intriguing differences between regulatory components characterized in yeast, mammals, and plants.
authors.affiliation: Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, D-50829 Cologne, Germany. Electronic address: hajheida@mpipz.mpg.de.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Hajheidari
authors.forename: Csaba
authors.initials: C
authors.lastname: Koncz
authors.forename: Dirk
authors.initials: D
authors.lastname: Eick
mesh_terms: D000818:Animals; D017360:Arabidopsis / Q000201:enzymology* / Q000235:genetics; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D008322:Mammals; D008954:Models, Biological; D010749:Phosphoprotein Phosphatases / Q000235:genetics; D010766:Phosphorylation; D011494:Protein Kinases / Q000235:genetics; D011499:Protein Processing, Post-Translational; D017434:Protein Structure, Tertiary; D012319:RNA Polymerase II / Q000235:genetics / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000235:genetics; D013045:Species Specificity; D014158:Transcription, Genetic
chemical_list: D029681:Arabidopsis Proteins; D011494:Protein Kinases; C060137:carboxy-terminal domain kinase; D012319:RNA Polymerase II; D010749:Phosphoprotein Phosphatases; C116022:carboxy-terminal domain phosphatase
keywords: CTD kinase; RNA polymerase II CTD; RNA processing; histone mark; miRNA; transcription