title: Development of children's hymenoptera venom allergy quality of life scale (CHVAQoLS).
abstract: BACKGROUND
  Venom allergy is a rare but life-threatening disease and may have a considerable impact on the health-related quality of life (HRQoL) of patients, especially children. This paper presents development of the HRQoL scale for children and adolescents with Hymenoptera venom allergy (HVA).
  
  
  METHODS
  The study sample consisted of 71 children, born between 1992 and 2000, who presented with a history of insect sting reaction when referred for consultation in the allergy center of Polish-American Children's Hospital, Krakow, Poland, during the period from 2000 to 2010. The initial pool of 60 items - divided into 6 domains - was prepared. The items with intercorrelations higher than 0.7 were removed from each domain and then principal component analysis was conducted for each domain separately, to provide a one-dimensional subscale for each domain. Reliability of the subscales was assessed using Cronbach alpha coefficient in terms of Classical Test Theory and with rho coefficient in terms of Item Response Theory. The multidimensionality of the scale was tested using multi-trait scaling.
  
  
  RESULTS
  Three to four items from each domain were subsequently selected to constitute six subscales. Rho coefficients for all the subscales reached 0.8, similar results were achieved with the Cronbach alpha coefficients. Multi-trait method showed that the majority of the items indicated stronger correlations with their own subscales than with other subscales, which proves that our constructed subscales measure different dimensions of HRQoL.
  
  
  CONCLUSIONS
  The presented scale comprises high validity and reliability subscales measuring six dimensions of HRQoL related to Hymenoptera venom allergy in children and adolescents. Such information may be useful in everyday clinical practice.
authors.affiliation: Department of Pediatrics, Polish-American Institute of Pediatrics, Jagiellonian University Medical College, Krakow, Poland. mijarosz@cyfronet.pl.
authors.forename: Ewa
authors.initials: E
authors.lastname: Cichocka-Jarosz
authors.forename: Piotr
authors.initials: P
authors.lastname: Brzyski
authors.forename: Beata
authors.initials: B
authors.lastname: Tobiasz-Adamczyk
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Lis
authors.forename: Jacek J
authors.initials: JJ
authors.lastname: Pietrzyk
references.citation: Arch Med Sci. 2012 Dec 20;8(6):1076-82
references.pmid: 23319984
references.citation: J Allergy Clin Immunol. 2002 Jan;109(1):162-70
references.pmid: 11799384
references.citation: Qual Life Res. 1996 Feb;5(1):27-34
references.pmid: 8901364
references.citation: Scand J Public Health. 2004;32(2):84-93
references.pmid: 15255497
references.citation: Przegl Lek. 2010;67(12):1237-42
references.pmid: 21591346
references.citation: Przegl Lek. 2010;67(12):1243-8
references.pmid: 21591347
references.citation: Qual Life Res. 1996 Feb;5(1):35-46
references.pmid: 8901365
references.citation: Health Qual Life Outcomes. 2007 Jan 03;5:1
references.pmid: 17201920
references.citation: J Clin Epidemiol. 1997 Mar;50(3):233-8
references.pmid: 9120521
references.citation: J Allergy Clin Immunol. 2008 Jul;122(1):139-44, 144.e1-2
references.pmid: 18602570
references.citation: Przegl Lek. 2012;69(12):1287-92
references.pmid: 23750441
references.citation: Psychol Bull. 1948 Nov;45(6):507-29
references.pmid: 18893224