title: Biventricular takotsubo cardiomyopathy: case report and general discussion.
abstract: In recent years, our understanding of the physiologic mechanisms of transient takotsubo cardiomyopathy has improved because of the growing use of emergent heart catheterization in patients who present with severe ischemic syndromes. However, even this procedure has revealed only that, in most patients with takotsubo syndrome, the sudden onset of ventricular dysfunction is not due to fixed coronary artery occlusions. We present a case of transient takotsubo cardiomyopathy with an exceptional feature--uneven impairment of both right and left ventricular function, or biventricular takotsubo--and we discuss a novel, comprehensive theory that we have devised to explain the pathophysiology of this syndrome's many manifestations.
authors.affiliation: Department of Cardiology, St. Luke's Episcopal Hospital, Houston, Texas 77030, USA. PAngelini@leachmancardiology.com
authors.forename: Paolo
authors.initials: P
authors.lastname: Angelini
authors.forename: Jorge
authors.initials: J
authors.lastname: Monge
authors.forename: Leo
authors.initials: L
authors.lastname: Simpson
mesh_terms: D000369:Aged, 80 and over; D002317:Cardiovascular Agents / Q000627:therapeutic use; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006439:Hemodynamics; D006801:Humans; D054549:Takotsubo Cardiomyopathy / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D016896:Treatment Outcome; D018497:Ventricular Dysfunction, Right / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D016277:Ventricular Function, Left / Q000187:drug effects; D016278:Ventricular Function, Right / Q000187:drug effects
chemical_list: D002317:Cardiovascular Agents
keywords: Acetylcholine/diagnostic use; angina pectoris, variant; coronary endothelial dysfunction; coronary vasospasm/physiopathology; takotsubo cardiomyopathy/classification/diagnosis/physiopathology; ventricular dysfunction, left/etiology/diagnosis; ventricular dysfunction, right/etiology/diagnosis
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