title: Right ventricular and septal function in patients with pulmonary hypertension.
abstract: OBJECTIVE
  Pulmonary hypertension (PHT) exacerbates the functions of both ventricles. This prospective, randomised study was planned to investigate the effects of PHT on kinetics of both ventricles and the septum.
  
  
  METHODS
  Twenty-five patients were randomly selected among the patients who had been planned to undergo mitral valve replacement (MVR) because of isolated mitral stenosis and divided into two groups according to their preoperative pulmonary artery pressure (PAP) values. Blood pool gated single photon emission tomography (BPGS) and transthoracic echocardiography were performed. Ventricles' regional, global and functional parameters were also assessed by using pulsed wave Doppler tissue imaging (DTI).
  
  
  RESULTS
  Preoperative and postoperative PAP of the group 1 (PAP < 50 mmHg) were 40.0 ± 2.8 and 30.0 ± 2.6 mmHg (p = 0.03), group 2 (PAP ≥ 50 mmHg) were 71.9 ± 4.7 and 50.6 ± 3.5 mmHg (p < 0.05). The global right and left ventricle scores were decreased after the operation. The decrement was only significant in group 2. Considering the septal kinetics, right ventricle septal score was decreased from 7.6 to 3.3 (p < 0.05) in group 1, from 3.8 to 1.6 (p < 0.05) in group 2 postoperatively.
  
  
  CONCLUSIONS
  Following MVR, a decrement in PAP values, and an improvement in ventricular function, especially in the right ventricular and septal kinetics were achieved. Furthermore, it was found that both DTI and BPGS techniques are beneficial to investigate the functional changes postoperatively and in the follow-up period of the patients who undergo mitral valve surgery.
authors.affiliation: Department of Cardiovascular Surgery, Türkiye Yüksek Ihtisas Hospital, Ankara, Turkey. Electronic address: uluss@yahoo.com.
authors.forename: A Tulga
authors.initials: AT
authors.lastname: Ulus
authors.forename: Nilüfer Yıldırım
authors.initials: NY
authors.lastname: Poyraz
authors.forename: Nurcan
authors.initials: N
authors.lastname: Arat
authors.forename: Seyhan
authors.initials: S
authors.lastname: Babaroğlu
authors.forename: A İhsan
authors.initials: Aİ
authors.lastname: Parlar
authors.forename: Soner
authors.initials: S
authors.lastname: Yavaş
authors.forename: Mustafa
authors.initials: M
authors.lastname: Unlü
mesh_terms: D000328:Adult; D005260:Female; D015637:Gated Blood-Pool Imaging; D006346:Heart Septum / Q000000981:diagnostic imaging / Q000503:physiopathology; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D008297:Male; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D011446:Prospective Studies; D016278:Ventricular Function, Right
keywords: Blood pool SPECT; Doppler tissue imaging; Mitral stenosis; Mitral valve replacement; Pulmonary artery hypertension