title: Demodex folliculitis presenting as periocular vesiculopustular rash.
abstract: OBJECTIVE
  To report an unusual case of Demodex folliculitis presenting as periocular vesiculopustular rash.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  A 68 year-old woman presented with a unilateral periocular rash that was initially treated by her primary ophthalmologist with topical steroids and antivirals. Slit-lamp examination revealed severe bilateral blepharitis, right greater than left, with waxy sleeves around the eyelashes. The diagnosis of Demodex infestation was considered. Treatment with daily lid scrub with polyhexamethylene biguanide (PHMB), 1,2-hexanediol and 1,2-octanediol (OCuSOFT PLUS) and erythromycin ointment twice a day resulted in complete resolution of the symptoms after 4 weeks.
  
  
  CONCLUSIONS
  Ophthalmologists should be aware of Demodex and consider it in the differential diagnosis of periocular skin lesions.
authors.affiliation: Department of Ophthalmology and Visual Sciences, Yale School of Medicine, New Haven , Connecticut , USA.
authors.forename: Samuel H
authors.initials: SH
authors.lastname: Yun
authors.forename: Flora
authors.initials: F
authors.lastname: Levin
authors.forename: Javier
authors.initials: J
authors.lastname: Servat
mesh_terms: D000368:Aged; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001645:Biguanides / Q000627:therapeutic use; D001762:Blepharitis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D004202:Disinfectants / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004917:Erythromycin / Q000627:therapeutic use; D005260:Female; D005499:Folliculitis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D006018:Glycols / Q000627:therapeutic use; D006586:Hexanes / Q000627:therapeutic use; D006801:Humans; D008924:Mite Infestations / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D008925:Mites; D000442:Octanols / Q000627:therapeutic use; D009824:Ointments; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology
chemical_list: D000900:Anti-Bacterial Agents; D001645:Biguanides; D004202:Disinfectants; D006018:Glycols; D006586:Hexanes; D000442:Octanols; D009824:Ointments; C535047:1,2-octanediol; C031233:polihexanide; D004917:Erythromycin; C119102:1,2-hexanediol