title: Is mesenteric panniculitis truely a paraneoplastic phenomenon? A matched pair analysis.
abstract: OBJECTIVE
  Mesenteric panniculitis (MP) is an underdiagnosed inflammatory condition of mesenteric adipose tissue. Prior studies suggested an association of MP with malignancy. To reassess this hypothesis, we performed the first matched case-control study comparing prevalence of malignancy and other disease in patients with and without MP.
  
  
  METHODS
  With a keyword search we identified CT examinations of MP patients between 2010 and 2012. Each MP patient was matched with two control patients for age, gender, abdominal diameter and CT protocol. Manifestation and extent of mesenteric panniculitis was classified independently by two investigators according to established criteria. Concomitant disease, laboratory parameters and follow up CTs were recorded and analyzed for all patients.
  
  
  RESULTS
  77 of 13485 CT patients were diagnosed with MP (prevalence 0.58%). 50.6% of MP patients suffered from malignancy vs. 60.2% in the control group (p=0.157). Over up to 4 years of follow up in 35 of these 77 MP patients no association between development of MP and the course of tumor diseases could be identified. There was also no significant difference in the rate of frequent concomitant diseases such as hypertension, diabetes or previous surgery between the two groups.
  
  
  CONCLUSIONS
  In this first case-control-study we could show that, contrary to previous reports, mesenteric panniculitis is neither paraneoplastic nor is it associated with other diseases.
authors.affiliation: Vivantes Klinikum Neukölln, Department for Radiology and Interventional Therapy, Berlin, Germany. Electronic address: Oezlem.Goegebakan@vivantes.de.
authors.forename: Ö
authors.initials: Ö
authors.lastname: Gögebakan
authors.forename: T
authors.initials: T
authors.lastname: Albrecht
authors.forename: M A
authors.initials: MA
authors.lastname: Osterhoff
authors.forename: A
authors.initials: A
authors.lastname: Reimann
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D016555:Matched-Pair Analysis; D008875:Middle Aged; D015436:Panniculitis, Peritoneal / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D010257:Paraneoplastic Syndromes / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D015203:Reproducibility of Results; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data*
keywords: Abdomen; CT; Inflammation; Mesenteric panniculitis; Mesentery; Neoplasm