title: Cocaine-induced postpartum coronary artery dissection: a case report and 80-year review of literature.
abstract: The incidence of cocaine-induced myocardial infarction (MI) in pregnancy is unknown. During the peripartum period, cocaine-abusing women are highly susceptible to MI caused by the effect of cocaine on a heart that is already stressed by hemodynamic changes of pregnancy. MI is an infrequent event during pregnancy and the peripartum period, with an estimated rate of 1 in 16,000 patients. Spontaneous coronary artery dissection (SCAD) can account for up to 27% of pregnancy-related MIs. We describe a case of MI diagnosed by increased troponin I levels in a postpartum patient with recent crack cocaine use in the setting of SCAD that required percutaneous coronary intervention of the left anterior descending and diagonal arteries. We also provide a comprehensive review of published literature related to this clinical entity.
authors.affiliation: Department of Cardiology, Louisiana State University Health Sciences Center in Shreveport, Shreveport, LA 71103, USA. pkatik@lsuhsc.edu
authors.forename: Pavan K
authors.initials: PK
authors.lastname: Katikaneni
authors.forename: Nuri I
authors.initials: NI
authors.lastname: Akkus
authors.forename: Neeraj
authors.initials: N
authors.lastname: Tandon
authors.forename: Kalgi
authors.initials: K
authors.lastname: Modi
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D003042:Cocaine / Q000009:adverse effects*; D003330:Coronary Vessel Anomalies / Q000139:chemically induced* / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D062645:Percutaneous Coronary Intervention; D049590:Postpartum Period; D016896:Treatment Outcome; D019210:Troponin I / Q000097:blood; D014652:Vascular Diseases / Q000139:chemically induced / Q000150:complications / Q000151:congenital* / Q000175:diagnosis
chemical_list: D015415:Biomarkers; D019210:Troponin I; D003042:Cocaine