title: Dissociable neural routes to successful prospective memory.
abstract: Identifying the processes by which people remember to execute an intention at an appropriate moment (prospective memory) remains a fundamental theoretical challenge. According to one account, top-down attentional control is required to maintain activation of the intention, initiate intention retrieval, or support monitoring. A diverging account suggests that bottom-up, spontaneous retrieval can be triggered by cues that have been associated with the intention and that sustained attentional processes are not required. We used a specialized experimental design and functional MRI methods to selectively marshal and identify each process. Results revealed a clear dissociation. One prospective-memory task recruited sustained activity in attentional-control areas, such as the anterior prefrontal cortex; the other engaged purely transient activity in parietal and ventral brain regions associated with attentional capture, target detection, and episodic retrieval. These patterns provide critical evidence that there are two neural routes to prospective memory, with each route emerging under different circumstances.
authors.affiliation: 1Department of Psychology, Washington University in St. Louis.
authors.forename: Mark A
authors.initials: MA
authors.lastname: McDaniel
authors.forename: Pamela
authors.initials: P
authors.lastname: Lamontagne
authors.forename: Stefanie M
authors.initials: SM
authors.lastname: Beck
authors.forename: Michael K
authors.initials: MK
authors.lastname: Scullin
authors.forename: Todd S
authors.initials: TS
authors.lastname: Braver
mesh_terms: D000293:Adolescent; D000328:Adult; D001288:Attention / Q000502:physiology; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods; D003463:Cues; D006801:Humans; D033182:Intention; D008279:Magnetic Resonance Imaging / Q000379:methods; D008568:Memory / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*; D055815:Young Adult
keywords: cognitive neuroscience; memory
references.citation: Neuropsychologia. 2014 Jan;52:37-50
references.pmid: 24200918
references.citation: Neuropsychologia. 2001;39(6):545-55
references.pmid: 11257280
references.citation: Nat Rev Neurosci. 2002 Mar;3(3):201-15
references.pmid: 11994752
references.citation: J Exp Psychol Learn Mem Cogn. 2010 Jul 1;36(4):1089-1095
references.pmid: 20852726
references.citation: J Exp Psychol Learn Mem Cogn. 2009 Jul;35(4):905-15
references.pmid: 19586260
references.citation: Brain. 2006 Mar;129(Pt 3):564-83
references.pmid: 16399806
references.citation: J Exp Psychol Learn Mem Cogn. 2004 May;30(3):605-14
references.pmid: 15099129
references.citation: J Exp Psychol Gen. 2005 Aug;134(3):327-42
references.pmid: 16131267
references.citation: Neuroimage. 2011 Jun 1;56(3):1655-65
references.pmid: 21376819
references.citation: J Exp Psychol Learn Mem Cogn. 2003 May;29(3):347-61
references.pmid: 12776746
references.citation: Neuropsychologia. 2006;44(12):2189-208
references.pmid: 16806314
references.citation: Trends Cogn Sci. 2007 Feb;11(2):49-57
references.pmid: 17188554
references.citation: Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):506-11
references.pmid: 10618448
references.citation: Neuropsychologia. 2011 Jul;49(8):2246-57
references.pmid: 21329712
references.citation: J Exp Psychol Learn Mem Cogn. 2010 May;36(3):736-49
references.pmid: 20438269
references.citation: Nat Rev Neurosci. 2008 Aug;9(8):613-25
references.pmid: 18641668
references.citation: Neuroimage. 1995 Jun;2(2):166-72
references.pmid: 9343599
references.citation: J Neurosci. 2007 Feb 28;27(9):2349-56
references.pmid: 17329432
references.citation: Cereb Cortex. 2009 May;19(5):1208-21
references.pmid: 18854581
references.citation: Neuroimage. 2012 Jul 16;61(4):1277-86
references.pmid: 22484411
references.citation: J Exp Psychol Learn Mem Cogn. 2010 Jul;36(4):1082-8; discussion 1089-95
references.pmid: 20565226
references.citation: J Exp Psychol Learn Mem Cogn. 2002 Jul;28(4):652-9
references.pmid: 12109759
references.citation: Neuroimage. 1997 Oct;6(3):218-29
references.pmid: 9344826
references.citation: Psychol Bull. 2000 Mar;126(2):247-59
references.pmid: 10748642
references.citation: Conscious Cogn. 2012 Dec;21(4):1644-53
references.pmid: 23064406
references.citation: Cogn Affect Behav Neurosci. 2003 Dec;3(4):255-74
references.pmid: 15040547
references.citation: Trends Cogn Sci. 2012 Feb;16(2):106-13
references.pmid: 22245618
references.citation: Neuroimage. 2010 Jan 1;49(1):865-74
references.pmid: 19744566
references.citation: Neuroimage. 2003 Aug;19(4):1694-708
references.pmid: 12948724
references.citation: Trends Cogn Sci. 2005 Sep;9(9):445-53
references.pmid: 16054861
references.citation: Cereb Cortex. 1999 Dec;9(8):815-23
references.pmid: 10601000
references.citation: J Cogn Neurosci. 2006 Jun;18(6):932-48
references.pmid: 16839301
references.citation: Hum Brain Mapp. 2005 May;25(1):46-59
references.pmid: 15846822
references.citation: Neuropsychologia. 2011 Jul;49(8):2147-55
references.pmid: 21192957