title: Acceptability and feasibility of serial HIV antibody testing during pregnancy/postpartum and male partner testing in Tororo, Uganda.
abstract: Our objective was to determine whether serial HIV testing during pregnancy and the postpartum period as well as male partner testing are acceptable and feasible in Tororo, Uganda. This was a prospective study of pregnant women at the Tororo District Hospital (TDH) Antenatal Clinic. Patients presenting for routine antenatal care were asked to participate in a serial HIV testing integrated into standard antenatal and postpartum/child immunization visits, and to invite their male partners for HIV testing. Serial testing was defined as ≥2 tests during pregnancy and ≥2 tests within 24 weeks postpartum. Of the 214 enrolled women, 80 (37%) completed serial testing, 176 (82%) had ≥2 tests, and 147 (69%) had ≥3 tests during the study period. One hundred eighty-two women (85%) accepted male partner testing, but only 19 men (10%) participated. One woman seroconverted during the study, for a cumulative HIV incidence of 0.5% (1/214). In multivariable logistic regression analysis, longer distance between home and clinic (aOR 0.87 [95% CI 0.79-0.97]) and not knowing household income (aOR 0.30 [95% CI 0.11-0.84]) were predictive of not completing serial testing. Higher level of education was associated with completing serial testing (linear trend p value = 0.05). In conclusion, partial serial HIV testing was highly acceptable and feasible, but completion of serial testing and male partner testing had poor uptake.
authors.affiliation: a The Department of Obstetrics, Gynecology & Reproductive Sciences , University of California , San Francisco , CA , USA.
authors.forename: Lena H
authors.initials: LH
authors.lastname: Kim
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Arinaitwe
authors.forename: Bridget
authors.initials: B
authors.lastname: Nzarubara
authors.forename: Moses R
authors.initials: MR
authors.lastname: Kamya
authors.forename: Tamara D
authors.initials: TD
authors.lastname: Clark
authors.forename: Pius
authors.initials: P
authors.lastname: Okong
authors.forename: Edwin D
authors.initials: ED
authors.lastname: Charlebois
authors.forename: Diane V
authors.initials: DV
authors.lastname: Havlir
authors.forename: Deborah
authors.initials: D
authors.lastname: Cohan
mesh_terms: D000328:Adult; D005240:Feasibility Studies; D005260:Female; D015483:HIV Antibodies / Q000032:analysis*; D006679:HIV Seropositivity / Q000175:diagnosis* / Q000523:psychology; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D008297:Male; D008403:Mass Screening / Q000523:psychology / Q000706:statistics & numerical data; D010342:Patient Acceptance of Health Care / Q000523:psychology / Q000706:statistics & numerical data*; D049590:Postpartum Period; D011247:Pregnancy; D011446:Prospective Studies; D012747:Sexual Partners / Q000523:psychology; D014454:Uganda / Q000453:epidemiology
chemical_list: D015483:HIV Antibodies