title: Unusual choroidal mass.
abstract: We present a unique case of disseminated tuberculosis presenting initially in the eye solely as a choroidal mass without any inflammation, mimicking choroidal metastasis. A 19-year-old girl presented with a large choroidal mass lesion in the right eye. Systemic examination revealed axillary lymphadenopathy. A fundus fluorescein angiography, positron emission tomography scan, abdominal ultrasonography and raised biochemical markers such as serum CA-125 pointed towards the diagnosis of choroidal metastases with primary in the ovaries. Fine needle aspiration cytology of the adnexal mass and ascitic fluid revealed granulomatous inflammation with a negative acid-fast bacilli stain. A multiplex PCR of ascitic fluid for the sequence MPB64 and IS6110 was positive for tuberculosis. The final diagnosis of disseminated tuberculosis was made and the patient subsequently showed a good response to antitubercular therapy.
authors.affiliation: Advanced Eye Centre, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors.forename: Swapnil Madhukar
authors.initials: SM
authors.lastname: Parchand
authors.forename: Kusum
authors.initials: K
authors.lastname: Sharma
authors.forename: Aman
authors.initials: A
authors.lastname: Sharma
authors.forename: Ramandeep
authors.initials: R
authors.lastname: Singh
mesh_terms: D015862:Choroid Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D014392:Tuberculosis, Ocular / Q000175:diagnosis*; D055815:Young Adult
references.citation: Indian J Med Res. 2011 Jul;134:40-6
references.pmid: 21808133
references.citation: Gynecol Oncol. 2006 Nov;103(2):565-9
references.pmid: 16740297
references.citation: Surv Ophthalmol. 2004 Jan-Feb;49(1):78-89
references.pmid: 14711441
references.citation: Br J Ophthalmol. 2011 Sep;95(9):1290-4
references.pmid: 20935307
references.citation: Surv Ophthalmol. 2007 Nov-Dec;52(6):561-87
references.pmid: 18029267
references.citation: Ocul Immunol Inflamm. 2006 Feb;14(1):35-40
references.pmid: 16507489
references.citation: BJOG. 2003 Dec;110(12):1129-31
references.pmid: 14664888
references.citation: Medicine (Baltimore). 2012 Jul;91(4):179-194
references.pmid: 22732948