title: Optimisation methodology in the chiral and achiral separation in electrokinetic chromatography in the case of a multicomponent sample of dansyl amino acids.
abstract: Two different chiral selectors synthesised in our laboratory were used to test the possibility of separation for a sample consisting of ten different enantiomeric pairs of dansyl-derivatives of α-amino acids in electrokinetic chromatography. It was possible to observe all the peaks, though only partly resolved, due to the twenty analytes through an accurate strategy of choice of the experimental conditions. As a part of this strategy, a procedure of identification of the single peaks in the electropherograms called LACI (lastly added component identification) has been developed.
authors.affiliation: Department of Chemical Sciences, University of Catania, viale A. Doria, 6, 95125 Catania, Italy. agiuffri@unict.it
authors.forename: Alessandro
authors.initials: A
authors.lastname: Giuffrida
authors.forename: Marianna
authors.initials: M
authors.lastname: Messina
authors.forename: Annalinda
authors.initials: A
authors.lastname: Contino
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Cucinotta
mesh_terms: D000596:Amino Acids / Q000032:analysis*; D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D003619:Dansyl Compounds / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D003619:Dansyl Compounds
keywords: Amino acids; Chiral separations; Cyclodextrin derivatives; Electrokinetic chromatography