title: Autism in a child with common variable immunodeficiency.
abstract: Autism is a neurodevelopmental disorder, characterized by poor social interaction and communication impairment and repetitive behavior. Autism is considered as a genetic and multifactorial disorder, with diverse risk factors involved.Herein, we report a 13-year-old male with common variable immunodeficiency (CVID), who was diagnosed with autism at the age of 3 years old. As there are some evidences about the role of the immune system defects in the pathogenesis of autism, specific primary antibody deficiency diseases such as CVID might predispose some affected cases to such neurodevelopmental disorders.
authors.affiliation: Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. ms.sadaghiani@gmail.com.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Salehi Sadaghiani
authors.forename: Asghar
authors.initials: A
authors.lastname: Aghamohammadi
authors.forename: Mahmoud-Reza
authors.initials: MR
authors.lastname: Ashrafi
authors.forename: Firozeh
authors.initials: F
authors.lastname: Hosseini
authors.forename: Hassan
authors.initials: H
authors.lastname: Abolhassani
authors.forename: Nima
authors.initials: N
authors.lastname: Rezaei
mesh_terms: D000293:Adolescent; D001321:Autistic Disorder / Q000209:etiology*; D017074:Common Variable Immunodeficiency / Q000150:complications*; D006801:Humans; D008297:Male