title: [Adiposity percentage relationship with hormone receptors immunoreactive score in breast cancer mexican women].
abstract: BACKGROUND
  Adipose tissue is an important estrogen resource and they are involved in breast cancer development.
  
  
  OBJECTIVE
  To establish the relationship between adiposity percentage and the estrogen and progesterone receptors immunoreactive score in Mexican women with breast cancer.
  
  
  METHODS
  This is a transversal and analytical study. We identified breast cancer women with cancer histologic diagnosis. We calculated: adiposity percentage and immunoreactive score. We performed correlation analysis between adiposity percentage, body mass index, diabetes mellitus and arterial hypertension, with estrogen and progesterone receptors in breast cancer samples. We perform logistic regression and Odds Ratio estimations.
  
  
  RESULTS
  We studied 43 patients with breast cancer and we observed association between adiposity percentage and estrogen and progesterone immnunoreactive score (rP 0.470; p 0.003 and rP 0.328; p 0.042, respectively). The most important risk factor in breast cancer positive to estrogen receptors was obesity (OR 19.1, IC95% 2.1 a 169.1, p 0.008), and previous obesity in breast cancer positive to progesterone receptors (OR 20.7, IC95% 2.3 a 185.9, p 0.007).
  
  
  CONCLUSIONS
  Adiposity percentage is an important risk factor to develop breast cancer positive to hormone receptors related with the risk of breast cancer positive to hormonal receptors.
authors.affiliation: Unidad de Investigación Médica en Epidemiología Clínica, Unidad Médica de Alta Especialidad, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Jalisco, México. luz.ma.adriana@gmail.com
authors.forename: Luz-Ma-Adriana
authors.initials: LM
authors.lastname: Balderas-Peña
authors.forename: Daniel
authors.initials: D
authors.lastname: Sat-Muñoz
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Castro Cervantes
authors.forename: Ricardo-Ernesto
authors.initials: RE
authors.lastname: Ramírez-Orozco
authors.forename: Wenceslao-Guillermo
authors.initials: WG
authors.lastname: Ángeles-Bueno
authors.forename: María-Rosa
authors.initials: MR
authors.lastname: Flores-Márquez
authors.forename: Griselda-Guadalupe
authors.initials: GG
authors.lastname: Macías-López
authors.forename: Sandra-Luz
authors.initials: SL
authors.lastname: Ruiz-Quezada
authors.forename: Ana-Leticia
authors.initials: AL
authors.lastname: Salcedo-Rocha
authors.forename: Javier-Eduardo
authors.initials: JE
authors.lastname: García de Alba-García
authors.forename: Pedro
authors.initials: P
authors.lastname: Solano-Murillo
mesh_terms: D050154:Adiposity / Q000502:physiology*; D000328:Adult; D000368:Aged; D001823:Body Composition / Q000502:physiology; D001943:Breast Neoplasms / Q000378:metabolism*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016015:Logistic Models; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D016017:Odds Ratio; D011960:Receptors, Estrogen / Q000276:immunology* / Q000378:metabolism; D011980:Receptors, Progesterone / Q000276:immunology* / Q000378:metabolism; D012307:Risk Factors
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone