title: Risk factors for incisional surgical site infections in elective surgery for colorectal cancer: focus on intraoperative meticulous wound management.
abstract: OBJECTIVE
  An incisional surgical site infection (I-SSI) is a frequently observed complication following colorectal surgery. Intraoperative wound management is one of the most important factors that determine the incidence of postoperative I-SSI. The purpose of this study was to assess the impact of the methods used for intraoperative wound management on the incidence of I-SSI following elective surgery for colorectal cancer.
  
  
  METHODS
  Between November 2009 and February 2011, the data of 1,980 consecutive patients who underwent elective colorectal resection for colorectal cancer were prospectively collected from 19 affiliated hospitals. The incidence of and risk factors for I-SSI were investigated.
  
  
  RESULTS
  Overall, 233 I-SSIs were identified (11.7 %). Forty-two possible risk factors were analyzed. Using a multivariate analysis, the independent risk factors for I-SSI were identified to be a high body mass index, previous laparotomy, chronic liver disease, wound length, contaminated wound class, creation or closure of an ostomy, right hemicolectomy procedure, the suture material used for fascial closure and the incidence of organ/space SSI.
  
  
  CONCLUSIONS
  To prevent I-SSI following elective colorectal surgery, it is crucial to avoid making large incisions and reduce fecal contamination whenever possible. A high quality randomized control trial is necessary to confirm the definitive intraoperative procedure(s) that can minimize the incidence of I-SSI.
authors.affiliation: The Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan.
authors.forename: Keita
authors.initials: K
authors.lastname: Itatsu
authors.forename: Gen
authors.initials: G
authors.lastname: Sugawara
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kaneoka
authors.forename: Takehito
authors.initials: T
authors.lastname: Kato
authors.forename: Eiji
authors.initials: E
authors.lastname: Takeuchi
authors.forename: Michio
authors.initials: M
authors.lastname: Kanai
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hasegawa
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Arai
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Yokoyama
authors.forename: Masato
authors.initials: M
authors.lastname: Nagino
mesh_terms: D000368:Aged; D015992:Body Mass Index; D015179:Colorectal Neoplasms / Q000601:surgery*; D013505:Digestive System Surgical Procedures / Q000379:methods; D017558:Elective Surgical Procedures / Q000379:methods; D005260:Female; D006801:Humans; D015994:Incidence; D007430:Intraoperative Care / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000517:prevention & control*
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