title: Measured versus self-reported physical function in adult survivors of childhood cancer.
abstract: OBJECTIVE
  Childhood cancer survivors (CCS) experience late effects that interfere with physical function. Limitations in physical function can affect CCS abilities to actively participate in daily activities. The purpose of this investigation was to evaluate the concordance between self-reported physical performance and clinically evaluated physical performance among adult CCS.
  
  
  METHODS
  CCS 18 yr or older and 10 yr or older from diagnosis who are participants in the St. Jude Lifetime cohort study responded to the physical function section of the Medical Outcome Survey Short Form (SF-36). Measured physical performance was evaluated using the Physical Performance Test and the 6-Minute Walk Test.
  
  
  RESULTS
  Individuals (N = 1778, 50.8% female) with a median time since diagnosis of 24.9 yr (range = 10.9-48.2) and a median age of 32.4 yr (range = 19.1-48.2) completed testing. Limitations in physical performance were self-reported by 14.1% of participants. The accuracy of self-report physical performance was 0.87 when the SF-36 was compared with the 6-Minute Walk Test or the Physical Performance Test. Reporting inaccuracies most often involved reporting a physical performance limitation. Poor accuracy was associated with previous diagnosis of a bone or CNS tumor, lymphoma, older age, and large body size.
  
  
  CONCLUSIONS
  These results suggest that self-report, using the physical performance subscale of the SF-36, correctly identifies CCS who do not have physical performance limitations. In contrast, this same measure is less able to identify individuals who have performance limitations.
authors.affiliation: 1Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN; 2Departments of Health, Exercise Science, and Recreation, University of Mississippi, University, MS; 3Department of Urology, The Ohio State University College of Medicine, Columbus, OH; and 4Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.
authors.forename: Webb A
authors.initials: WA
authors.lastname: Smith
authors.forename: Zhenghong
authors.initials: Z
authors.lastname: Li
authors.forename: Mark
authors.initials: M
authors.lastname: Loftin
authors.forename: Brent E
authors.initials: BE
authors.lastname: Carlyle
authors.forename: Melissa M
authors.initials: MM
authors.lastname: Hudson
authors.forename: Leslie L
authors.initials: LL
authors.lastname: Robison
authors.forename: Kirsten K
authors.initials: KK
authors.lastname: Ness
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D015992:Body Mass Index; D001859:Bone Neoplasms / Q000503:physiopathology; D016543:Central Nervous System Neoplasms / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D005080:Exercise Test; D005260:Female; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008223:Lymphoma / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000503:physiopathology*; D011237:Predictive Value of Tests; D057566:Self Report; D017741:Survivors; D016138:Walking / Q000502:physiology*; D055815:Young Adult
references.citation: BMJ. 1997 May 31;314(7094):1580-3
references.pmid: 9169401
references.citation: Eur Heart J. 2000 Apr;21(7):540-9
references.pmid: 10775009
references.citation: Pediatr Pulmonol. 1996 Aug;22(2):85-9
references.pmid: 8875580
references.citation: Ann Intern Med. 2005 Nov 1;143(9):639-47
references.pmid: 16263886
references.citation: Spine (Phila Pa 1976). 2000 Dec 15;25(24):3130-9
references.pmid: 11124729
references.citation: Gerontologist. 2007 Dec;47(6):838-44
references.pmid: 18192637
references.citation: Br Med J (Clin Res Ed). 1982 May 29;284(6329):1607-8
references.pmid: 6805625
references.citation: Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1588-95
references.pmid: 16030088
references.citation: Eur Respir J. 2008 Mar;31(3):571-8
references.pmid: 17989117
references.citation: Qual Life Res. 2005 Feb;14(1):259-64
references.pmid: 15789959
references.citation: Arch Gerontol Geriatr. 2012 Mar-Apr;54(2):e57-62
references.pmid: 21890222
references.citation: J Public Health (Oxf). 2005 Sep;27(3):281-91
references.pmid: 15870099
references.citation: Arch Phys Med Rehabil. 2008 Jan;89(1):128-36
references.pmid: 18164342
references.citation: Clin Rehabil. 2006 Jan;20(1):83-90
references.pmid: 16502754
references.citation: Am J Respir Crit Care Med. 2000 Apr;161(4 Pt 1):1396
references.pmid: 10764338
references.citation: J Gerontol A Biol Sci Med Sci. 1997 Jan;52(1):M19-26
references.pmid: 9008665
references.citation: PLoS One. 2012;7(10):e47944
references.pmid: 23082232
references.citation: J Thorac Oncol. 2009 May;4(5):602-7
references.pmid: 19276833
references.citation: BMJ. 1994 Jun 11;308(6943):1552
references.pmid: 8019315
references.citation: Ann Epidemiol. 2006 Mar;16(3):197-205
references.pmid: 16137893
references.citation: J Geriatr Phys Ther. 2010 Jan-Mar;33(1):16-8
references.pmid: 20503729
references.citation: Curr Opin Pediatr. 2007 Feb;19(1):23-31
references.pmid: 17224658
references.citation: N Engl J Med. 2006 Oct 12;355(15):1572-82
references.pmid: 17035650
references.citation: Int J Cancer. 2007 Aug 1;121(3):633-40
references.pmid: 17405119
references.citation: J Clin Oncol. 2009 May 10;27(14):2382-9
references.pmid: 19332713
references.citation: Am J Public Health. 1992 Jun;82(6):841-5
references.pmid: 1533995
references.citation: Eur J Heart Fail. 2003 Jun;5(3):247-52
references.pmid: 12798821
references.citation: J Am Geriatr Soc. 1990 Oct;38(10):1105-12
references.pmid: 2229864
references.citation: Pediatr Blood Cancer. 2013 May;60(5):856-64
references.pmid: 23024097
references.citation: Am J Epidemiol. 1999 Feb 1;149(3):228-35
references.pmid: 9927217
references.citation: J Gerontol A Biol Sci Med Sci. 2000 Jun;55(6):M350-5
references.pmid: 10843356
references.citation: Health Qual Life Outcomes. 2006 Oct 05;4:77
references.pmid: 17022814
references.citation: Am J Respir Crit Care Med. 1998 Nov;158(5 Pt 1):1384-7
references.pmid: 9817683
references.citation: Soc Sci Med. 1994 Apr;38(7):937-42
references.pmid: 8202742