title: [Diagnosis and management of laryngeal verrucous carcinoma (case report in one patient and literature review)].
abstract: OBJECTIVE
  To investigate the clinical, pathological character and differential diagnosis of laryngeal verrucous carcinoma.
  
  
  METHODS
  Clinical data of one case with laryngeal verrucous carcinoma in our hospital were retrospectively analyzed.
  
  
  RESULTS
  The diagnosis of verrucous carcinoma was difficult and depend on repeated biopsy. Verrucous carcinoma of larynx is a highly differentiated variant of squamous carcinoma that has peculiar clinical and morphological features. The basement membrane is not invaded. It is prone to distant metastasis, than to local recurrence. The case underwent the partial laryngectomy, and was followed up for more than 4 years with no recurrence.
  
  
  CONCLUSIONS
  Verrucous carcinoma of the larynx is a special pattern of the well-differentiated squamous cancer. A correct diagnosis requires close cooperation between the laryngologist and the pathologist. The main treatment of verrucous carcinoma is complete surgical excision to reserve larynx function as far as possible and improve the quality of life.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Lv
authors.forename: Hui
authors.initials: H
authors.lastname: Yang
authors.forename: Yuanzhi
authors.initials: Y
authors.lastname: Zhu
authors.forename: Shixi
authors.initials: S
authors.lastname: Liu
mesh_terms: D018289:Carcinoma, Verrucous / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies