title: Screening of biological activities of Polygonum maritimum L. from Algerian coast.
abstract: OBJECTIVE
  To investigate the antioxidant and the antibacterial activities of crude extract from aerial part of Polygonum maritimum L. (Polygonaceae) (P. maritimum) and to find new actives biomolecules.
  
  
  METHODS
  The whole plant was collected from the Rechgoune coast (West of Algeria), and methanolic crude extract of aerial parts of P. maritimum (PMCE) was prepared. The extract was tested against different bacterial strain and tested for his ability to neutralize free radical (DPPH) and to scavenge the H2O2.
  
  
  RESULTS
  PMCE had a very high content of total phenol, which was (352.49±18.03) mg/g dry weight, expressed as gallic acid equivalent. PMCE exhibited excellent antioxidant activity, as measured using DPPH and H2O2 scavenging assays. It also showed a high antibacterial activity against gram-positive bacterial strains: Bacillus cereus, Bacillus subtilis and Staphylococcus aureus with an highest MIC of 120 µg/mL.
  
  
  CONCLUSIONS
  The antioxidant and antibacterial activity of the PMCE is probably due to phenolic compounds present in the extract. The contemporary presence of antioxidant and antibacterial activities in the PMCE suggests that this plant may be a source of bioactive substances with multifaceted activity.
authors.affiliation: Laboratoire des Produits Naturels, BP 119, Imama 13000, Université Abou Bekr Belkaid-Tlemcen- Algérie. imad.elhaci@mail.univ-tlemcen.dz
authors.forename: Imad Abdelhamid
authors.initials: IA
authors.lastname: El-Haci
authors.forename: Fawzia Atik
authors.initials: FA
authors.lastname: Bekkara
authors.forename: Wissame
authors.initials: W
authors.lastname: Mazari
authors.forename: Fayçal
authors.initials: F
authors.lastname: Hassani
authors.forename: Mohamed Amine
authors.initials: MA
authors.lastname: Didi
mesh_terms: D000462:Algeria; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D005419:Flavonoids / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010636:Phenols / Q000494:pharmacology*; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D028502:Polygonum / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts
keywords: Antibacterial activity; Antioxidant activity; Phenolic compounds; Polygonum maritimum L.
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