title: Proposal for the use in emergency departments of cardiac troponins measured with the latest generation methods in patients with suspected acute coronary syndrome without persistent ST-segment elevation.
abstract: The purpose of this document is to develop recommendations on the use of the latest generation of cardiac troponins in emergency room settings for the diagnosis of myocardial infarction in patients with suspected acute coronary syndrome (ACS) without persistent ST-segment elevation (NSTE-ACS). The main points which have been addressed reaching a consensus are represented by: Suitability and appropriateness of the terminology. Appropriateness of the request. Confirmation of the diagnosis of myocardial infarction (rule-in). Exclusion of the diagnosis of myocardial infarction (rule-out).
  
  
  METHODS
  Each point has been analyzed by taking into account the evidence presented in medical publications. Recommendations were developed using the criteria adopted by the European Society of Cardiology and the American Heart Association/American College of Cardiology (www.escardio.org/guidelines). Each point of the recommendation was submitted for validation to an external audit by a Group of Experts (named above).
authors.forename: Ivo
authors.initials: I
authors.lastname: Casagranda
authors.forename: Mario
authors.initials: M
authors.lastname: Cavazza
authors.forename: Aldo
authors.initials: A
authors.lastname: Clerico
authors.forename: Marcello
authors.initials: M
authors.lastname: Galvani
authors.forename: Filippo
authors.initials: F
authors.lastname: Ottani
authors.forename: Martina
authors.initials: M
authors.lastname: Zaninotto
authors.forename: Luigi Maria
authors.initials: LM
authors.lastname: Biasucci
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Cervellin
authors.forename: Tiziano
authors.initials: T
authors.lastname: Lenzi
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lippi
authors.forename: Mario
authors.initials: M
authors.lastname: Plebani
authors.forename: Marco
authors.initials: M
authors.lastname: Tubaro
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology; D000367:Age Factors; D000789:Angina, Unstable / Q000097:blood / Q000175:diagnosis; D004562:Electrocardiography; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D012737:Sex Factors; D019210:Troponin I / Q000097:blood*; D020107:Troponin T / Q000097:blood*
chemical_list: D019210:Troponin I; D020107:Troponin T