title: Deep brain stimulation in nonparkinsonian movement disorders and emerging technologies, targets, and therapeutic promises in deep brain stimulation.
abstract: This article focuses on the evolution of deep brain stimulation (DBS) targets within the brain, beginning with the discovery of DBS's potential in non-Parkinson disease movement disorders. DBS has gained in popularity and applicability for a growing number of neuropathologic conditions with neural network disorders and dysfunction. Targets within the brain have been based frequently on historical sites used for ablative surgeries in years past, derived from experiment and experience but also have arisen via elucidation of neural networks, transmitter function and location, disease neuropathology, and also, fortuitous discovery.
authors.affiliation: Department of Neurological Surgery, Loyola University Medical Center, 2150 South 1st Avenue, Room 2700, Maywood, IL 60153, USA. dander1@lumc.edu
authors.forename: Douglas
authors.initials: D
authors.lastname: Anderson
authors.forename: Ninith
authors.initials: N
authors.lastname: Kartha
mesh_terms: D046690:Deep Brain Stimulation / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009069:Movement Disorders / Q000628:therapy*
keywords: Deep brain stimulation; Dystonia; Essential tremor; Movement disorders; Tourette syndrome