title: Evaluation of the radial artery applanation tonometry technology for continuous noninvasive blood pressure monitoring compared with central aortic blood pressure measurements in patients with multiple organ dysfunction syndrome.
abstract: OBJECTIVE
  We compared blood pressure (BP) measurements obtained using radial artery applanation tonometry with invasive BP measurements using a catheter placed in the abdominal aorta through the femoral artery in patients with multiple organ dysfunction syndrome (MODS).
  
  
  METHODS
  In 23 intensive care unit patients with MODS, we simultaneously assessed BP values for 15 minutes per patient using radial artery applanation tonometry (T-Line TL-200 pro device; Tensys Medical Inc, San Diego, Calif) and the arterial catheter (standard-criterion technique). A total of 2879 averaged 10-beat epochs were compared using Bland-Altman plots.
  
  
  RESULTS
  The mean difference ± SD (with corresponding 95% limits of agreement) between radial artery applanation tonometry-derived BP and invasively assessed BP was +1.0 ± 5.5 mm Hg (-9.9 to +11.8 mm Hg) for mean arterial pressure, -3.3 ± 11.2 mm Hg (-25.3 to +18.6 mm Hg) for systolic arterial pressure, and +4.9 ± 7.0 mm Hg (-8.8 to +18.6 mm Hg) for diastolic arterial pressure, respectively.
  
  
  CONCLUSIONS
  In intensive care unit patients with MODS, mean arterial pressure and diastolic arterial pressure can be determined accurately and precisely using radial artery applanation tonometry compared with central aortic values obtained using a catheter placed in the abdominal aorta through the femoral artery. Although systolic arterial pressure could also be derived accurately, wider 95% limits of agreement suggest lower precision for determination of systolic arterial pressure.
authors.affiliation: II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Strasse 22, 81675 München, Germany.
authors.forename: Agnes S
authors.initials: AS
authors.lastname: Meidert
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Huber
authors.forename: Alexander
authors.initials: A
authors.lastname: Hapfelmeier
authors.forename: Miriam
authors.initials: M
authors.lastname: Schöfthaler
authors.forename: Johannes N
authors.initials: JN
authors.lastname: Müller
authors.forename: Nicolas
authors.initials: N
authors.lastname: Langwieser
authors.forename: Julia Y
authors.initials: JY
authors.lastname: Wagner
authors.forename: Roland M
authors.initials: RM
authors.lastname: Schmid
authors.forename: Bernd
authors.initials: B
authors.lastname: Saugel
mesh_terms: D000368:Aged; D001011:Aorta / Q000502:physiology*; D062186:Arterial Pressure / Q000502:physiology*; D001795:Blood Pressure Determination / Q000295:instrumentation / Q000379:methods*; D003422:Critical Care / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods*; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods*; D009102:Multiple Organ Failure / Q000503:physiopathology*; D017534:Radial Artery / Q000502:physiology*
keywords: Diastolic blood pressure; Hemodynamic monitoring; Mean arterial pressure; Systolic blood pressure; T-Line