title: Rapid intra-hepatic dissemination of hepatocellular carcinoma with pulmonary metastases following combined loco-regional therapy.
abstract: This manuscript describes an unusual case of rapid intra-hepatic dissemination of hepatocellular carcinoma with pulmonary metastases occurring 1 month after combined chemoembolization and radiofrequency ablation. Inferior vena cava and portal vein invasion tumor thrombus was also detected, possibly accounting for the mechanism of disease dissemination route of disease.
authors.affiliation: Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore. druei@yahoo.com
authors.forename: Uei
authors.initials: U
authors.lastname: Pua
mesh_terms: D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001706:Biopsy; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D017115:Catheter Ablation / Q000009:adverse effects*; D016461:Chemoembolization, Therapeutic / Q000009:adverse effects*; D054893:Cone-Beam Computed Tomography; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology* / Q000628:therapy; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary*; D008297:Male
chemical_list: D000970:Antineoplastic Agents
keywords: Chemoembolization; Hepatocellular carcinoma; Metastases; Radiofrequency ablation
references.citation: World J Gastroenterol. 2004 Apr 15;10(8):1137-40
references.pmid: 15069713
references.citation: Am J Surg. 2004 Aug;188(2):165-7
references.pmid: 15249243
references.citation: World J Gastroenterol. 2005 Nov 21;11(43):6828-32
references.pmid: 16425391
references.citation: Hepatol Int. 2009 Sep;3(3):509-15
references.pmid: 19669252