title: [Possibilities of remaxol in prevention of toxic hepatitis during chemotherapy for cancer patients].
abstract: The effectiveness of planning polychemotherapy (PCT) for cancer patients depends on the functional state of the liver. The use of remaxol was studied in 100 patients with advanced forms of cancer (including breast cancer) in a preventive mode in comparison with the control group (100 patients, essentiale group of 40 patients) and in the process of PCT. Remaxol, compared with the control group, allowed reducing the frequency of drug hepatotoxicity by 30 +/- 3.7% and by 6.5 +/- 2.9% in comparison with the group of patients who received essentiale.
authors.forename: V G
authors.initials: VG
authors.lastname: Cherenkov
authors.forename: A B
authors.initials: AB
authors.lastname: Petrov
authors.forename: T M
authors.initials: TM
authors.lastname: Vasil'eva
authors.forename: M M
authors.initials: MM
authors.lastname: Strozhenkov
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects*; D000975:Antioxidants / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy*; D018579:Patient Selection; D010713:Phosphatidylcholines / Q000627:therapeutic use; D020011:Protective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D013386:Succinates / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000975:Antioxidants; D010713:Phosphatidylcholines; D020011:Protective Agents; C555877:Remaxol; D013386:Succinates; C011246:essential 303 forte