title: Nephrolithiasis: nutrition as cause or therapeutic tool.
abstract: Nephrolithiasis is a very common disease with an increasing prevalence among industrialized populations. Kidney stone formation is a complex phenomenon, involving genetic and metabolic patterns, and nutrition can play an important role in this match both as a promoter or as a protective factor. To promote a deeper knowledge of such a challenging disease, clinicians and researchers have met in Rome, Italy, last March 2013, at the International Congress "Nephrolithiasis: a systemic disorder" to discuss patho-physiology and possible treatment of kidney stones. During the meeting, a whole session was dedicated to nutrition, seen both as a cause or a therapeutic tool for nephrolithiasis. Due to its etiopathogenesis, nephrolithiasis is also an ideal model for a nutrigenetics and nutrigenomics approach. Nutrigenomics and nutrigenetic respectively study the effects of a dietary treatment on gene expression and, on the other hand, the impact of an inherited trait on the response to a specific dietary treatment.
authors.affiliation: Department of Health Sciences, Università degli Studi di Milano, via A, Di Rudini 8, 20142, Milano, Italy. irene.brenna@unimi.it
authors.forename: Irene
authors.initials: I
authors.lastname: Brenna
authors.forename: Elena
authors.initials: E
authors.lastname: Dogliotti
authors.forename: Annalisa
authors.initials: A
authors.lastname: Terranegra
authors.forename: Benedetta
authors.initials: B
authors.lastname: Raspini
authors.forename: Laura
authors.initials: L
authors.lastname: Soldati
mesh_terms: D057890:Epigenomics; D005260:Female; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D006801:Humans; D007669:Kidney Calculi / Q000628:therapy; D008297:Male; D053040:Nephrolithiasis / Q000209:etiology* / Q000628:therapy*; D054647:Nutrigenomics; D009752:Nutritional Status; D015995:Prevalence
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