title: High-grade glioma: refined diagnostics steering stratified therapy.
abstract: An adequately sampled tumor histology that is evaluated by an experienced neuropathologist is the current international standard for the diagnosis of high-grade gliomas. We present the case of a 30-year-old female for whom clinical and radiological information dramatically changed the histological diagnosis. We suggest a new algorithm including these parameters to refine the accuracy of histological diagnosis both for standard treatment and centrally reviewed clinical trials.
authors.affiliation: Department of Neurology and Wilhelm Sander NeuroOncology Unit, University Hospital Regensburg, Regensburg, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Uhl
authors.forename: Peter
authors.initials: P
authors.lastname: Hau
keywords: Glioblastoma; Histology; MRI
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