title: Ductus venosus versus cerebral transverse sinus Doppler velocimetry for predicting acidemia at birth in pregnancies complicated by placental insufficiency.
abstract: OBJECTIVE
  The objectives of this study is to compare ductus venosus (DV) and cerebral transverse sinus (CTS) Doppler velocimetry for predicting acidemia at birth in pregnancies complicated by placental insufficiency.
  
  
  METHODS
  A prospective cross-sectional study involving 69 cases. Doppler assessment of the DV and CTS was carried out in the last 24 hours prior to delivery. The sensitivity, specificity, positive and negative predictive values, and the accuracy and false-positive and false-negative rates were calculated for those parameters considered to be good predictors of acidemia. The McNemar test was used to compare the various parameters.
  
  
  RESULTS
  The DV pulsatility index(PI), S/A, and (S - A)/S ratios as well as the CTS PI and the (S - A)/S ratio were good predictors of acidemia. The comparison between DV and CTS showed that for pulsatility index for veins, the sensitivity was 52.4% versus 66.7%, p = 0.508; the specificity was 81.2% versus 77.1%, p = 0.774; and the accuracy was 72.5% versus 73.9%, p = 1.00. For the (S - A)/S ratio the sensitivity was 52.4% versus 52.4%, p = 1.00; the specificity was 85.4% versus 79.2%, p = 0.508; and the accuracy was 75.4% versus 71%, p = 0.647.
  
  
  CONCLUSIONS
  In pregnancies with placental insufficiency, the PI and the (S - A)/S ratio of both DV and CTS were equally effective in predicting acidemia at birth.
authors.affiliation: Assis Chateaubriand Maternity Teaching Hospital, Federal University of Ceará (UFC), Fortaleza, Brazil.
authors.forename: Manoel
authors.initials: M
authors.lastname: Martins Neto
authors.forename: Francisco Herlânio Costa
authors.initials: FH
authors.lastname: Carvalho
authors.forename: Maurício Mendes
authors.initials: MM
authors.lastname: Barbosa
authors.forename: Rosa Maria Salani
authors.initials: RM
authors.lastname: Mota
authors.forename: Denise Teixeira
authors.initials: DT
authors.lastname: de Menezes
authors.forename: Carlos Geraldo Viana
authors.initials: CG
authors.lastname: Murta
authors.forename: Renato Martins
authors.initials: RM
authors.lastname: Santana
authors.forename: Antonio Fernandes
authors.initials: AF
authors.lastname: Moron
mesh_terms: D000138:Acidosis / Q000175:diagnosis* / Q000209:etiology; D003430:Cross-Sectional Studies; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D017078:Laser-Doppler Flowmetry; D010927:Placental Insufficiency / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D011446:Prospective Studies; D011673:Pulsatile Flow; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal; D014469:Umbilical Arteries; D014680:Veins / Q000196:embryology*