title: Towards quantum simulations of biological information flow.
abstract: Recent advances in the spectroscopy of biomolecules have highlighted the possibility of quantum coherence playing an active role in biological energy transport. The revelation that quantum coherence can survive in the hot and wet environment of biology has generated a lively debate across both the physics and biology communities. In particular, it remains unclear to what extent non-trivial quantum effects are used in biology and what advantage, if any, they afford. We propose an analogue quantum simulator, based on currently available techniques in ultra-cold atom physics, to study a model of energy and electron transport based on the Holstein Hamiltonian. By simulating the salient aspects of a biological system in a tunable laboratory set-up, we hope to gain insight into the validity of several theoretical models of biological quantum transport in a variety of relevant parameter regimes.
authors.affiliation: Blackett Laboratory, Imperial College London, London, UK ; Clarendon Laboratory, University of Oxford, Oxford, UK.
authors.forename: Ross
authors.initials: R
authors.lastname: Dorner
authors.forename: John
authors.initials: J
authors.lastname: Goold
authors.forename: Vlatko
authors.initials: V
authors.lastname: Vedral
keywords: biological transport; quantum biology; quantum simulation
references.citation: Science. 1996 Aug 23;273(5278):1073-8
references.pmid: 8688088
references.citation: Science. 2009 Oct 2;326(5949):108-11
references.pmid: 19797653
references.citation: J Chem Phys. 2009 Jun 21;130(23):234111
references.pmid: 19548715
references.citation: Science. 2011 Oct 7;334(6052):57-61
references.pmid: 21885735
references.citation: J Chem Phys. 2008 Nov 7;129(17):174106
references.pmid: 19045332
references.citation: Philos Trans A Math Phys Eng Sci. 2012 Aug 13;370(1972):3771-86
references.pmid: 22753825
references.citation: J Phys Chem B. 2011 Feb 17;115(6):1531-7
references.pmid: 21268616
references.citation: J Chem Phys. 2011 Sep 21;135(11):114501
references.pmid: 21950865
references.citation: Nature. 2009 Nov 5;462(7269):74-7
references.pmid: 19890326
references.citation: Proc Natl Acad Sci U S A. 1974 Sep;71(9):3640-4
references.pmid: 16592178
references.citation: Nature. 2007 Apr 12;446(7137):782-6
references.pmid: 17429397
references.citation: Science. 2006 Mar 10;311(5766):1430-6
references.pmid: 16469879
references.citation: Nature. 2007 Apr 12;446(7137):740-1
references.pmid: 17429387
references.citation: Philos Trans A Math Phys Eng Sci. 2010 Aug 13;368(1924):3581-92
references.pmid: 20603369
references.citation: Phys Rev Lett. 2009 Oct 9;103(15):150601
references.pmid: 19905615
references.citation: Nature. 2008 Jun 5;453(7196):736-8
references.pmid: 18528388
references.citation: Nature. 2002 Jan 3;415(6867):39-44
references.pmid: 11780110
references.citation: Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):12766-70
references.pmid: 20615985
references.citation: Phys Rev Lett. 2011 Sep 16;107(12):120501
references.pmid: 22026760
references.citation: Nature. 2006 Oct 19;443(7113):787-95
references.pmid: 17051205
references.citation: Science. 2010 Jul 30;329(5991):547-50
references.pmid: 20558666