title: Plasma cells for hire: prior experience required.
abstract: Activation of IgG⁺ memory B cells accounts for much of the antibodies in secondary immune responses. Here, Kometani et al. (2013) demonstrate that reduced amounts of Bach2 in antigen-experienced memory B cells control the robust production of IgG1⁺ plasma cells.
authors.affiliation: Integrated Department of Immunology, K516B, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA. hagmanj@njhealth.org
authors.forename: James
authors.initials: J
authors.lastname: Hagman
authors.forename: Kara
authors.initials: K
authors.lastname: Lukin
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D050976:Basic-Leucine Zipper Transcription Factors / Q000276:immunology*; D002454:Cell Differentiation / Q000276:immunology*; D010950:Plasma Cells / Q000276:immunology*
chemical_list: C102109:Bach2 protein, mouse; D050976:Basic-Leucine Zipper Transcription Factors
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