title: Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging.
abstract: A novel nano-conjugate containing ultrasmall water-soluble AuNCs protected by ovalbumin as the fluorescent part, folic acid as the targeting ligand and a homopolymer N-acryloxysuccinimide as the linker has been investigated. Moreover, specific staining of HeLa cells by the nano-conjugate has been demonstrated.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems Institute of Chemistry, Chinese Academy of Sciences, No. 2 Zhongguancun Beiyijie, 100190, P. R. China.
authors.forename: Juan
authors.initials: J
authors.lastname: Qiao
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Mu
authors.forename: Li
authors.initials: L
authors.lastname: Qi
authors.forename: Jingjing
authors.initials: J
authors.lastname: Deng
authors.forename: Lanqun
authors.initials: L
authors.lastname: Mao
mesh_terms: D016503:Drug Delivery Systems; D005456:Fluorescent Dyes / Q000737:chemistry*; D005492:Folic Acid / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D008856:Microscopy, Fluorescence; D057054:Molecular Imaging; D015394:Molecular Structure; D009369:Neoplasms / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013194:Staining and Labeling
chemical_list: D005456:Fluorescent Dyes; D011108:Polymers; D006046:Gold; D005492:Folic Acid