title: Cation effect on slow release from alginate beads: a fluorescence study.
abstract: In this study, spherical alginate beads containing pyranine (P y ) as a fluorescence probe were prepared by ionotropic gelation of a sodium alginate solution. The steady state fluorescence technique was used to study pyranine release from the alginate beads crosslinked with calcium, barium and aluminum ions, respectively. The slow release of P y was observed with the time drive mode of the spectrophotometer at 512 nm. Fluorescence emission intensity (I p ) from P y was monitored during the release process, and the encapsulation efficiency (EE) of pyranine from the alginate beads was calculated. The Fickian Diffusion model was used to measure the release coefficients, D sl . It was seen that the slow release coefficients of pyranine from the alginate beads crosslinked with Ca(2+), Ba(2+), and Al(3+) ions increased in the following order: D sl (Al(3+))> D sl (Ca(2+))> D sl (Ba(2+)). In contrast, the initial amount of pyranine and EE into the beads showed the reverse behavior.
authors.affiliation: Faculty of Science and Letters, Istanbul Technical University, 34469, Maslak, Istanbul, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Kaygusuz
authors.forename: F Bedia
authors.initials: FB
authors.lastname: Erim
authors.forename: Onder
authors.initials: O
authors.lastname: Pekcan
authors.forename: Gülşen
authors.initials: G
authors.lastname: Akın Evingür
mesh_terms: D000464:Alginates / Q000737:chemistry*; D001190:Arylsulfonates / Q000138:chemical synthesis / Q000737:chemistry*; D002412:Cations / Q000138:chemical synthesis / Q000737:chemistry; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D013050:Spectrometry, Fluorescence
chemical_list: D000464:Alginates; D001190:Arylsulfonates; D002412:Cations; D005456:Fluorescent Dyes; D006603:Hexuronic Acids; D020723:Glucuronic Acid; C005047:pyranine
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