title: Modification of antimicrobial prophylaxis based on rectal culture results to prevent fluoroquinolone-resistant Escherichia coli infections after prostate biopsy.
abstract: For patients undergoing transrectal ultrasound-guided biopsy of the prostate (TRUBP), use of rectal screening culture results to guide antimicrobial prophylaxis was effective for prevention of fluoroquinolone-resistant Escherichia coli infections. In practice, elimination of infections after TRUBP required the rectal screening protocol and addition of gentamicin for patients missing prior screening.
authors.affiliation: Department of Medicine, Division of Infectious Diseases and HIV Medicine, University Hospitals of Cleveland, Cleveland, Ohio, USA.
authors.forename: Nuntra
authors.initials: N
authors.lastname: Suwantarat
authors.forename: Donald M
authors.initials: DM
authors.lastname: Dumford
authors.forename: Rafael
authors.initials: R
authors.lastname: Ponce-Terashima
authors.forename: Sirisha
authors.initials: S
authors.lastname: Kundrapu
authors.forename: Trina F
authors.initials: TF
authors.lastname: Zabarsky
authors.forename: Hui
authors.initials: H
authors.lastname: Zhu
authors.forename: Curtis J
authors.initials: CJ
authors.lastname: Donskey
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000379:methods*; D001706:Biopsy / Q000009:adverse effects* / Q000379:methods; D024881:Drug Resistance, Bacterial; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D024841:Fluoroquinolones / Q000627:therapeutic use*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000382:microbiology / Q000473:pathology*; D012007:Rectum / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones