title: Primary orbital chronic granulomatous reaction to deep staphylococcal infection due to trauma in immunocompetent.
abstract: A 53-year-old man presented with a slow-growing mass in the right orbit and temporal area of 1 year duration following a road traffic accident. Examination revealed a nodular fungating mass involving the orbit, right temporal area with multiple discharging sinuses causing proptosis and restricted ocular motility. The patient denied light perception in the right eye. There was exposure keratopathy and optic atrophy. Imaging showed mass lesion of the orbit extending intracranially. Tissue biopsy and culture revealed a chronic granulomatous reaction due to deep infection with coagulase-positive staphylococci. The patient showed remarkable improvement to systemic antibiotics and anticonvulsants. Mortality is high in such cases due to intracranial extension if there is a delay in treatment. This case report summarises a rare aetiology and successful treatment of a case of chronic granulomatous reaction due to deep bacterial infection following trauma and is deemed rare as cases of primary orbital infection in immunocompetent have not been reported so far.
authors.affiliation: Department of Ophthalmology, Kasturba Medical College, Manipal, Karnataka, India.
authors.forename: Lavanya G
authors.initials: LG
authors.lastname: Rao
authors.forename: Sarita R J
authors.initials: SR
authors.lastname: Gonsalves
authors.forename: Atiya
authors.initials: A
authors.lastname: Pathan
authors.forename: Akansha
authors.initials: A
authors.lastname: Sinha
mesh_terms: D002908:Chronic Disease; D006259:Craniocerebral Trauma / Q000150:complications; D006099:Granuloma / Q000382:microbiology*; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008875:Middle Aged; D009916:Orbital Diseases / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000150:complications* / Q000209:etiology
references.citation: J Oral Maxillofac Surg. 1995 May;53(5):599-605
references.pmid: 7722732
references.citation: J Am Acad Dermatol. 1991 Mar;24(3):393-6
references.pmid: 2061434
references.citation: Int J Dermatol. 1996 Jun;35(6):381-8
references.pmid: 8737868
references.citation: Indian J Dent Res. 2007 Jul-Sep;18(3):131-4
references.pmid: 17687177
references.citation: Am J Pathol. 1959 Jan-Feb;35(1):153-67
references.pmid: 13617416
references.citation: J Laryngol Otol. 1997 Jan;111(1):77-9
references.pmid: 9292141
references.citation: J Clin Pathol. 1998 May;51(5):399-400
references.pmid: 9708210