title: Fluorescent organic nanocrystals and non-doped nanoparticles for biological applications.
abstract: The recently developed fluorescent organic nanocrystals and non-doped nanoparticles (FONs) occupy a special position among other nanoparticle systems that are used for studying a variety of fundamental processes in the life sciences. Understanding their particular photophysical behavior allows proper design of FONs. The usual preparation methods are described. It is shown that FONs lead to original applications as biochemical sensors and biolabels for immunoassays. They also show high potentialities for bio-imaging of cell cultures, drug-delivery control, angiography and in vivo bio-imaging of solid tumors.
authors.affiliation: CNRS, ITAV-USR 3505, Advanced Technology Institute in Life Sciences, 1 place Pierre Potier, Oncopole-BP 50624, 31106 Toulouse, France. suzanne.fery-forgues@itav-recherche.fr
authors.forename: Suzanne
authors.initials: S
authors.lastname: Fery-Forgues
mesh_terms: D000818:Animals; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry; D004247:DNA / Q000737:chemistry; D004337:Drug Carriers / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D007118:Immunoassay; D051379:Mice; D018613:Microscopy, Confocal; D041681:NIH 3T3 Cells; D053758:Nanoparticles / Q000737:chemistry*; D009369:Neoplasms / Q000000981:diagnostic imaging; D011092:Polyethylene Glycols / Q000737:chemistry; D011859:Radiography; D019265:Spectroscopy, Near-Infrared
chemical_list: D002593:Cetrimonium Compounds; D004337:Drug Carriers; D005456:Fluorescent Dyes; D011092:Polyethylene Glycols; D004247:DNA; D000077286:Cetrimonium