title: Rewiring immunity: generating a functional thymus from hESCs… are we there yet?
abstract: Two papers in this issue of Cell Stem Cell have made a significant advance in solving one of the great challenges of modern immunology-resurrecting thymus function through the induction of thymus epithelial cells (TECs) by directed differentiation of human embryonic stem cells (hESCs).
authors.affiliation: Department of Anatomy and Developmental Biology, Monash University, Clayton, 3800, Victoria, Australia. richard.boyd@monash.edu
authors.forename: Richard L
authors.initials: RL
authors.lastname: Boyd
authors.forename: Chew-Li
authors.initials: CL
authors.lastname: Soh
authors.forename: Nicholas R
authors.initials: NR
authors.lastname: Boyd
authors.forename: Edouard G
authors.initials: EG
authors.lastname: Stanley
authors.forename: Ann P
authors.initials: AP
authors.lastname: Chidgey
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D060833:Cellular Microenvironment; D053595:Embryonic Stem Cells / Q000166:cytology*; D004847:Epithelial Cells / Q000166:cytology*; D004848:Epithelium / Q000254:growth & development*; D006801:Humans; D013601:T-Lymphocytes / Q000166:cytology*; D013950:Thymus Gland / Q000166:cytology* / Q000254:growth & development*