title: Infectious endotheliitis: a rare case of presumed mycotic origin.
abstract: OBJECTIVE
  To report an interesting case of infectious endotheliitis of presumed mycotic origin.
  
  
  METHODS
  A case report of a 56-year-old male farmer who sought medical attention after a month-long evolution of irritative symptoms in his right eye, accompanied by visual acuity (VA) impairment. The patient received topical and oral broad-spectrum antibiotic treatment with no improvement before being referred to a cornea specialist, where he was found to have VA of 20/150 and was noted on biomicroscopy to have endothelial feathery coalescent lesions. The patient was admitted to the hospital for an aqueous humor sample and intravenous voriconazole.
  
  
  RESULTS
  The microbiological studies did not isolate any micro-organisms. However, clinical evidence of improvement was confirmed after 5 days of antimycotic intravenous therapy. Complete clinical resolution was achieved at 1 month after treatment completion with oral voriconazole, as evidenced by VA of 20/20 and disappearance of endothelial lesions.
  
  
  CONCLUSIONS
  Endothelial involvement by fungi is a rare condition. In this case, no microbes were isolated, but the characteristic morphology of the lesions, the history of onychomycosis, and the spectacular response to voriconazole turn this case into a valid presumptive diagnosis.
authors.affiliation: Department of Ophthalmology Hospital Pablo Tobón Uribe.
authors.forename: Luis Fernando
authors.initials: LF
authors.lastname: Zapata
authors.forename: José David
authors.initials: JD
authors.lastname: Paulo
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Restrepo
authors.forename: Luis Fernando
authors.initials: LF
authors.lastname: Velásquez
authors.forename: Andrés E Toro
authors.initials: AE
authors.lastname: Montoya
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Zapata
keywords: endotheliitis; keratitis; mycotic; voriconazole
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