title: [Role of androgen in the elderly. Current status of development of selective androgen receptor modulator].
abstract: The research to develop a drug, so called selective androgen receptor modulator (SARM) , which shows beneficial androgenic action on bone and muscle, but hardly possesses the stimulatory action on prostate has been making a progress. However, no drug is available in the market at present. Most of such drugs are developed, aiming at the application to age-related muscle reduction (sarcopenia) and osteoporosis. We are now trying to develop a SARM which may have beneficial effect on metabolic syndrome.
authors.affiliation: Department of Endocrinology and Diabetes Mellitus, School of Medicine, Fukuoka University, Japan.
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Yanase
mesh_terms: D000368:Aged; D000375:Aging; D000726:Androgen Antagonists / Q000494:pharmacology*; D000728:Androgens / Q000378:metabolism*; D000818:Animals; D004195:Disease Models, Animal; D055808:Drug Discovery; D006801:Humans; D011944:Receptors, Androgen / Q000378:metabolism*
chemical_list: D000726:Androgen Antagonists; D000728:Androgens; D011944:Receptors, Androgen