title: Churg-Strauss syndrome presenting with eosinophilic myocarditis: a diagnostic challenge.
abstract: Churg-Strauss syndrome (CSS) is an unusual disease that presents as systemic vasculitis and peripheral eosinophilia in patients with an atopic constitution. Cardiac involvement is unusual and often not prominent on initial presentation, but is an important cause of morbidity and mortality in patients with CSS. We report the case of a young woman with severe acute myocarditis. Coronary arteriography demonstrated extensive focal vasculopathy, consistent with coronary vasculitis, and myocardial biopsy showed eosinophilic myocarditis. This presentation led to an initial diagnosis of CSS in this patient and appropriate therapy resulted in a spectacular remission of disease activity.
authors.affiliation: Cardiology Department, Centro Hospitalar de São João, Porto, Portugal. Electronic address: sofiakorreia@gmail.com.
authors.forename: Ana Sofia
authors.initials: AS
authors.lastname: Correia
authors.forename: Alexandra
authors.initials: A
authors.lastname: Gonçalves
authors.forename: Vítor
authors.initials: V
authors.lastname: Araújo
authors.forename: João
authors.initials: J
authors.lastname: Almeida e Silva
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Pereira
authors.forename: Pedro
authors.initials: P
authors.lastname: Rodrigues Pereira
authors.forename: Manuel
authors.initials: M
authors.lastname: Pizarro
authors.forename: João Carlos
authors.initials: JC
authors.lastname: Silva
authors.forename: Maria Júlia
authors.initials: MJ
authors.lastname: Maciel
mesh_terms: D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000175:diagnosis*; D004802:Eosinophilia / Q000209:etiology*; D005260:Female; D006801:Humans; D009205:Myocarditis / Q000209:etiology*; D055815:Young Adult
keywords: Churg–Strauss syndrome; Complete reversal of cardiac involvement; Coronary vasculitis; Eosinophilic myocarditis; Miocardite eosinofílica; Reversão completa do envolvimento cardíaco; Síndrome de Churg–Strauss; Vasculite coronária