title: Selective deprotection method of N-phenylcarbamoyl group.
abstract: We report an improved method for the selective deprotection of the N-phenylcarbamoyl group, which yields the corresponding alcohol without affecting other protecting groups. Deprotection was performed using di-tert-butyl dicarbonate and tetra-n-butylammonium nitrite (Boc2O and Bu4NNO2) in pyridine at room temperature. This method is also effective for deprotecting the fluorous N-phenylcarbamoyl group.
authors.affiliation: Department of Material and Life Chemistry, Faculty of Engineering, Kanagawa University, Rokkakubashi, Kanagawa-ku, Yokohama 221-8686, Japan. akais001@kanagawa-u.ac.jp
authors.forename: Shoji
authors.initials: S
authors.lastname: Akai
authors.forename: Rika
authors.initials: R
authors.lastname: Tanaka
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Hoshi
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Sato
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*
chemical_list: D000438:Alcohols; D011725:Pyridines