title: Recent acquisitions in the medical treatment of infertility caused by Chlamydia Trachomatis.
abstract: The infertility defined as the incapacity of the people to conceive a child in a given period, usually of 1-2 years of sexually unprotected relations, represents a major dysfunction of the genital apparatus. Its frequency is estimated at 10-15% of the couples at the reproductive age. The incidence of sterility is high, a couple out of 10 being sterile. The conjugal sterility is a phenomenon representative for the couple; the woman is responsible for it only in 35-40% of the cases, in 40% of the cases, the male factor is involved. In 20% of the cases, mixed factors are met, both feminine and masculine, and in 5-10% of the cases, the causes cannot be detected. From the multitude of causes of infertility, the infectious factor plays an important role, the Chlamydia infections being lately blamed in the etiology of sterility. The infections due to Chlamydia Trachomatis (CT) represent the most frequent sexually transmitted diseases, which, most of the times lead to sterility. Taking into account the widespread of this bacterium in the sexually active population, the effective treatment of the CT infection is very important. We have selected 200 cases with PID genital infection in the study. All the selected patients had at least 2, 3 and more than 3 inflammation recurrence episodes, this way being considered cases with medium and severe forms of disease. All these selected patients had at least 2, 3 and more than 3 episodes of inflammation recurrence, this way being considered medium and severe disease cases. In conclusion, there is a high clinical efficiency of the azithromycin treatment in PID case.
authors.affiliation: Ghencea Medical Center, Bucharest, Romania. alina_almoushaly@yahoo.com
authors.forename: A
authors.initials: A
authors.lastname: Al-Moushaly
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017963:Azithromycin / Q000627:therapeutic use; D002690:Chlamydia Infections / Q000188:drug therapy / Q000503:physiopathology*; D002692:Chlamydia trachomatis / Q000187:drug effects / Q000472:pathogenicity*; D005260:Female; D006801:Humans; D007246:Infertility / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D011247:Pregnancy
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin
keywords: Azithromycin; Chlamydia Trachomatis; genital infection; infertility; pregnancy
references.citation: Am J Obstet Gynecol. 1991 Jun;164(6 Pt 2):1771-81
references.pmid: 2039031
references.citation: JAMA. 2003 Oct 1;290(13):1767-70
references.pmid: 14519712
references.citation: Hum Reprod Update. 1998 Nov-Dec;4(6):891-903
references.pmid: 10098479
references.citation: Obstet Gynecol. 2003 Nov;102(5 Pt 1):934-9
references.pmid: 14672466
references.citation: Sex Transm Dis. 1998 Jan;25(1):5-11
references.pmid: 9437777
references.citation: Hum Reprod. 2003 Sep;18(9):1841-7
references.pmid: 12923136
references.citation: J Eur Acad Dermatol Venereol. 2009 Dec;23(12):1353-63
references.pmid: 19522706
references.citation: J Clin Microbiol. 2007 May;45(5):1395-402
references.pmid: 17376879