title: A headache presenting in the emergency room, a clinical manifestation of an unfortunate diagnosis (grade III left frontal anaplastic ependymoma with 1p deletion).
abstract: An 18-year-old girl presented with a headache and behavioural changes. She was found to have a frontal mass. Neuroimaging revealed an intra-axial mass, located at the left frontal cortical/subcortical region approximately 6×7, 5×7, 5 cm (TxApxL), having a heterogeneous density with cysts and calcification. She had total gross excision of the neoplasm. Histopathological examination revealed an anaplastic ependymoma. Fluorescence in situ hybridisation, a molecular cytogenetic test, reported deletion of 1p without deletion of 19q. The patient had a good postoperative improvement.
authors.affiliation: Department of Rheumatology Service, Puerta de Hierro Hospital Majadahonda, Madrid, Spain. aldolasa@hotmail.com
authors.forename: B J
authors.initials: BJ
authors.lastname: Flores-Robles
authors.forename: A R
authors.initials: AR
authors.lastname: Hurtarte-Sandoval
authors.forename: R M
authors.initials: RM
authors.lastname: Harrison
authors.forename: C C
authors.initials: CC
authors.lastname: Cuevas
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D004636:Emergency Service, Hospital; D004806:Ependymoma / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D005260:Female; D005625:Frontal Lobe; D017353:Gene Deletion; D006261:Headache / Q000209:etiology; D006801:Humans; D060787:Neoplasm Grading
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