title: Levels of selenium, zinc, copper, and cardiac troponin I in serum of patients with acute coronary syndrome.
abstract: The aim of this study was to assess the levels of selenium (Se), zinc (Zn), copper (Cu), and troponin I (TnI) in patients with acute coronary syndrome (ACS) on admission to our emergency department in comparison to healthy control subjects. Patients with diagnosed ACS (n = 100) were included in the study group. Control subjects (n = 100) were selected from healthy volunteers in the same age range. Venous blood samples were obtained to evaluate the levels of Se, Zn, Cu, and TnI (on admission for the ACS group). Serum Se, Zn, and Cu levels were significantly less in the ACS group compared to the control group (p <0.001, p <0.01, and p <0.001, respectively). The serum TnI level was significantly greater in the ACS group compared to the control group (p <0.05). The serum Se level in the ACS group correlated significantly with the TnI level (r = -0.211, p = 0.035). These results indicate that Se, Zn, and Cu deficiencies may be risk factors for ACS, and a decreased serum Se level in patients with ACS might reflect the degree of myocardial necrosis.
authors.affiliation: Emergency Department, Selçuk University Faculty of Medicine, Selçuk, Konya, Turkey. aysegulbayir@hotmail.com
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Bayır
authors.forename: Hasan
authors.initials: H
authors.lastname: Kara
authors.forename: Aysel
authors.initials: A
authors.lastname: Kıyıcı
authors.forename: Bahadır
authors.initials: B
authors.lastname: Oztürk
authors.forename: Fikret
authors.initials: F
authors.lastname: Akyürek
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003300:Copper / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010343:Patient Admission; D012307:Risk Factors; D012643:Selenium / Q000097:blood*; D019210:Troponin I / Q000097:blood*; D015032:Zinc / Q000097:blood*
chemical_list: D019210:Troponin I; D003300:Copper; D012643:Selenium; D015032:Zinc