title: Towards a detailed atlas of protein-protein interactions.
abstract: Protein interaction maps are the key to understand the complex world of biological processes inside the cell. Public protein databases have already catalogued hundreds of thousands of experimentally discovered interactions, and struggle to curate all the existing information dispersed through the literature. However, to be most efficient, standard protocols need to be implemented for direct submission of new interaction sets directly into databases. At the same time, great efforts are invested to expand the coverage of the interaction space and unveil the molecular details of such interactions up to the atomistic level. The net result will be the definition of a detailed atlas spanning the universe of protein interactions to guide the everyday work of the biologist.
authors.affiliation: Joint IRB-BSC Program in Computational Biology, Institute for Research in Biomedicine (IRB Barcelona), c/Baldiri Reixac 10-12, Barcelona 08028, Spain.
authors.forename: Roberto
authors.initials: R
authors.lastname: Mosca
authors.forename: Tirso
authors.initials: T
authors.lastname: Pons
authors.forename: Arnaud
authors.initials: A
authors.lastname: Céol
authors.forename: Alfonso
authors.initials: A
authors.lastname: Valencia
authors.forename: Patrick
authors.initials: P
authors.lastname: Aloy
mesh_terms: D019295:Computational Biology; D006801:Humans; D025941:Protein Interaction Mapping / Q000379:methods*; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*
chemical_list: D011506:Proteins