title: Base excess as a predictor for injury severity in pediatric trauma patients.
abstract: BACKGROUND
  Base excess is considered a predictor of mortality and severity of injury in trauma patients. Base excess had been widely examined in different settings. Only few studies have examined the role of base excess in pediatric trauma patients.
  
  
  OBJECTIVE
  To evaluate the value of admission base excess in pediatric trauma patients with respect to intensive care unit (ICU) admission rate and length of hospital stay.
  
  
  METHODS
  A retrospective study of pediatric trauma patients was conducted at a Level II trauma center. All patients aged 0-16 years for which a trauma team was activated over the years 2006-2009 were included. Study database included admission base excess, mechanism of injury, location and nature of injury, injury severity score, length of hospital stay, and ICU admission.
  
  
  RESULTS
  The study group consisted of 359 patients. There was a weak linear correlation between admission base excess, length of stay in the hospital, and ICU admission. Base excess seemed to show a stronger correlation for the youngest age group (0-6 years) and no correlation for the middle age group. There was a positive but weak correlation (R Spearman = 0.26) between admission base excess and Injury Severity Score (ISS). However, 40% of the children with an ISS score >25 had normal admission base excess values. The area under the curve of the receiver operating characteristic curves of base excess for predicting ICU admission was 0.66.
  
  
  CONCLUSIONS
  The admission base excess in pediatric trauma patients seems to be a weak prognostic factor in our facility.
authors.affiliation: Pediatric Emergency Unit, Assaf Harofeh Medical Center, Zerifin, Israel; Sackler Faculty of Medicine Tel Aviv University, Tel Aviv, Israel.
authors.forename: Yochai
authors.initials: Y
authors.lastname: Levi
authors.forename: Igor
authors.initials: I
authors.lastname: Jeroukhimov
authors.forename: Kobi
authors.initials: K
authors.lastname: Peleg
authors.forename: Michael
authors.initials: M
authors.lastname: Rozenfeld
authors.forename: Itai
authors.initials: I
authors.lastname: Shavit
authors.forename: Eran
authors.initials: E
authors.lastname: Kozer
mesh_terms: D000137:Acid-Base Imbalance / Q000097:blood*; D000293:Adolescent; D000367:Age Factors; D019540:Area Under Curve; D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003422:Critical Care; D005260:Female; D006801:Humans; D007223:Infant; D015601:Injury Severity Score; D007902:Length of Stay; D008297:Male; D011379:Prognosis; D012372:ROC Curve; D012189:Retrospective Studies; D014947:Wounds and Injuries / Q000097:blood*
chemical_list: D015415:Biomarkers
keywords: base excess; injury severity; pediatrics; trauma