title: Randomized trial of a presurgical scheduled reduced smoking intervention for patients newly diagnosed with cancer.
abstract: OBJECTIVE
  Cancer patients who smoke are advised to quit smoking to reduce treatment complications and future cancer risk. This study's main objective was to evaluate the efficacy of a novel, presurgical cessation intervention in newly diagnosed cancer patients scheduled for surgical hospitalization.
  
  
  METHODS
  We conducted a parallel-arm, randomized controlled trial comparing the efficacy of our hospital-based, tobacco cessation "best practices" treatment model (BP; cessation counseling and nicotine replacement therapy) with BP enhanced by a behavioral tapering regimen (scheduled reduced smoking; BP + SRS) administered by a handheld computer before hospitalization for surgery. Cessation outcomes were short (hospital admission and 3 months) and longer-term (6 months) biochemically verified smoking abstinence. We hypothesized that BP + SRS would be superior to BP alone. One hundred eighty-five smokers were enrolled.
  
  
  RESULTS
  Overall, 7-day-point prevalence, confirmed abstinence rates at 6 months for BP alone (32%) and BP + SRS (32%) were high; however, no main effect of treatment was observed. Patients who were older and diagnosed with lung cancer were more likely to quit smoking.
  
  
  CONCLUSIONS
  Compared to best practices for treating tobacco dependence, a presurgical, scheduled reduced smoking intervention did not improve abstinence rates among newly diagnosed cancer patients.reserved).
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center.
authors.forename: Jamie S
authors.initials: JS
authors.lastname: Ostroff
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center.
authors.forename: Jack E
authors.initials: JE
authors.lastname: Burkhalter
authors.affiliation: Department of Behavioral Sciences, MD Anderson Cancer Center.
authors.forename: Paul M
authors.initials: PM
authors.lastname: Cinciripini
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center.
authors.forename: Yuelin
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center.
authors.forename: Mariya P
authors.initials: MP
authors.lastname: Shiyko
authors.affiliation: MD Anderson Cancer Center.
authors.forename: Cho Y
authors.initials: CY
authors.lastname: Lam
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Hay
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center.
authors.forename: Lara K
authors.initials: LK
authors.lastname: Dhingra
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Lord-Bessen
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center.
authors.forename: Susan M
authors.initials: SM
authors.lastname: Holland
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center.
authors.forename: Ruth
authors.initials: R
authors.lastname: Manna
mesh_terms: D000368:Aged; D003376:Counseling; D055317:Evidence-Based Practice; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000175:diagnosis* / Q000601:surgery; D011300:Preoperative Care; D016540:Smoking Cessation / Q000379:methods* / Q000706:statistics & numerical data*; D000074606:Smoking Prevention; D061485:Tobacco Use Cessation Devices; D016896:Treatment Outcome
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