title: The use of cannabinoids in chronic pain.
abstract: We present the case of a 56-year-old man who developed chronic pain following the excision of a facial cancer that was poorly controlled despite multiple analgesic medications. Following the starting of nabilone (a synthetic cannabinoid) his pain control was greatly improved and this had a huge impact on his quality of life. We also managed to significantly reduce his doses of opioid analgesia and ketamine. We review the current literature regarding the medicinal use of cannabinoids, with an emphasis on chronic pain, in an attempt to clarify their role and how to select patients who may benefit from this treatment.
authors.affiliation: University Hospital of Wales, Cardiff, UK. reynoldstd@doctors.org.uk
authors.forename: Timothy David
authors.initials: TD
authors.lastname: Reynolds
authors.forename: Hannah Louise
authors.initials: HL
authors.lastname: Osborn
mesh_terms: D000700:Analgesics / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D059350:Chronic Pain / Q000517:prevention & control*; D013759:Dronabinol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008048:Lip Neoplasms / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000517:prevention & control; D013365:Submandibular Gland Neoplasms / Q000601:surgery
chemical_list: D000700:Analgesics; C011941:nabilone; D013759:Dronabinol
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