title: Diffuse anaplastic leptomeningeal oligodendrogliomatosis mimicking neurosarcoidosis.
abstract: Diffuse leptomeningeal oligodendrogliomatosis is a rare, frequently fatal CNS malignancy that most often affects children.1Although potentially treatable with chemotherapy and radiation, the radiologic findings are nonspecific and pathologic confirmation of the diagnosis is difficult. We describe an adult patient whose initial presentation mimicked neurosarcoidosis. Despite extensive imaging abnormalities, 3 biopsies were required before the diagnosis of diffuse leptomeningeal oligodendrogliomatosis was confirmed.
authors.affiliation: Departments of Neurology (A.N.L.H., A.J.A.), Neurosurgery (F.B.M.), Radiology (J.M.M.), and Pathology (J.E.P., C.G.), Mayo Clinic College of Medicine, Rochester, MN; and the Department of Neurological Sciences (R.K.Z.) and the Division of Neurosurgery (W.E.T.), Nebraska Medical Center, Omaha.
authors.forename: Andrea N
authors.initials: AN
authors.lastname: Leep Hunderfund
authors.forename: Rana K
authors.initials: RK
authors.lastname: Zabad
authors.forename: Allen J
authors.initials: AJ
authors.lastname: Aksamit
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Morris
authors.forename: Fredric B
authors.initials: FB
authors.lastname: Meyer
authors.forename: William E
authors.initials: WE
authors.lastname: Thorell
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Parisi
authors.forename: Caterina
authors.initials: C
authors.lastname: Giannini
references.citation: Eur Neurol. 2009;62(1):16-22
references.pmid: 19407451
references.citation: AJNR Am J Neuroradiol. 2000 Jun-Jul;21(6):1122-6
references.pmid: 10871026
references.citation: J Neuropathol Exp Neurol. 1951 Jan;10(1):16-29
references.pmid: 14804124
references.citation: J Neurol Sci. 2009 Dec 15;287(1-2):267-70
references.pmid: 19751941
references.citation: Acta Neuropathol. 2012 Nov;124(5):627-41
references.pmid: 22941225
references.citation: J Neurooncol. 2007 Jan;81(1):75-9
references.pmid: 17077938