title: [Utility of endoscopic ultrasound-guided fine needle aspiration for diagnosis of Burkitt lymphoma in two pediatric cases].
abstract: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) was performed as a diagnostic procedure for two pediatric patients with intra-abdominal tumors. Case 1 was an 8-year-old boy with a huge tumor in the portal-hepatic region. Case 2 was a 17-year-old girl with a history of diabetes and recurrent relapse of Burkitt lymphoma, who had a newly developing tumor in the pancreatic body. In both cases, EUS-FNA was performed as a less invasive diagnostic procedure than open biopsy or total resection of the tumor. Tumor cells were determined to be of the B cell lineage by flow cytometric and immunostaining analyses. Both cases were diagnosed as having Burkitt lymphoma based on detection of IgH/C-MYC translocation by FISH. The aspiration was successfully conducted without severe complications, and both patients were immediately given chemotherapy. EUS-FNA is a safe and minimally invasive procedure with high diagnostic value for pediatric cases with intra-abdominal tumors.
authors.affiliation: Department of Pediatrics, Graduate School of Medicine, Kyoto University.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Hamabata
authors.forename: Katsutsugu
authors.initials: K
authors.lastname: Umeda
authors.forename: Seishiro
authors.initials: S
authors.lastname: Noudomi
authors.forename: Tomoo
authors.initials: T
authors.lastname: Daifu
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Morishima
authors.forename: Satoshi
authors.initials: S
authors.lastname: Saida
authors.forename: Eitaro
authors.initials: E
authors.lastname: Hiejima
authors.forename: Itaru
authors.initials: I
authors.lastname: Kato
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Hiramatsu
authors.forename: Ken-ichiro
authors.initials: K
authors.lastname: Watanabe
authors.forename: Akira
authors.initials: A
authors.lastname: Kurita
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Kodama
authors.forename: Toshio
authors.initials: T
authors.lastname: Heike
authors.forename: Souichi
authors.initials: S
authors.lastname: Adachi
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D000293:Adolescent; D044963:Biopsy, Fine-Needle / Q000379:methods; D002051:Burkitt Lymphoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D002648:Child; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D016896:Treatment Outcome