title: Perfectionism and physical disability predict depression in multiple sclerosis.
abstract: OBJECTIVE
  The relationship between depression and physical disability in multiple sclerosis (MS) is unclear. This investigation examines the interaction between disability and perfectionism in predicting depression in MS.
  
  
  METHODS
  Participants (n=51) completed the frost multidimensional perfectionism scale (FMPS), the Chicago multiscale depression inventory (CMDI), and the Expanded Disability Status Scale (EDSS).
  
  
  RESULTS
  Regression revealed that the FMPS×EDSS interaction predicted depression above the variance predicted by each variable alone. Perfectionism predicted depression at high levels of disability.
  
  
  CONCLUSIONS
  Our results suggest a means of reconciling inconsistent findings regarding physical disability and depression in MS and offer a potential target for psychotherapy.
authors.affiliation: Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1000, USA. megan-m-smith@uiowa.edu
authors.forename: Megan M
authors.initials: MM
authors.lastname: Smith
authors.forename: Peter A
authors.initials: PA
authors.lastname: Arnett
mesh_terms: D000328:Adult; D003863:Depression / Q000150:complications / Q000523:psychology*; D003866:Depressive Disorder / Q000150:complications / Q000523:psychology*; D004185:Disability Evaluation; D006233:Persons with Disabilities / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications / Q000523:psychology*; D010551:Personality; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life
keywords: Depression; Multiple sclerosis; Neuropsychology; Physical disability