title: Effect of fluoride concentration in adhesives on morphology of acid-base resistant zones.
abstract: This study aimed to investigate the effect of fluoride concentration in adhesives on morphology of acid-base resistant zone (ABRZ). Seven experimental adhesives with different concentrations of NaF (0 wt%; F0 to 100 wt%: F100) were prepared based on the formulation of a commercially available adhesive (Clearfil Protect Bond, F100). The resin-dentin interface of the bonded specimen was subjected to demineralizing solution and NaOCl, sectioned, polished and argon-ion etched for SEM observation. Fluoride release from each adhesive was measured using an ion-selective electrode. Fluoride ion release from the adhesive linearly increased with higher NaF concentration. The ABRZ area increased significantly with higher NaF concentration except for F0, F10, and F20 (p<0.05). F100 showed the largest ABRZ, where a slope of acid-resistant dentin was clearly observed at the bottom of the ABRZ. The concentration of NaF in the two-step self-etching adhesive resin influenced the amount of dentin structure remaining after acid-challenge.
authors.affiliation: Cariology and Operative Dentistry, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
authors.forename: Masaru
authors.initials: M
authors.lastname: Kirihara
authors.forename: Go
authors.initials: G
authors.lastname: Inoue
authors.forename: Toru
authors.initials: T
authors.lastname: Nikaido
authors.forename: Masaomi
authors.initials: M
authors.lastname: Ikeda
authors.forename: Alireza
authors.initials: A
authors.lastname: Sadr
authors.forename: Junji
authors.initials: J
authors.lastname: Tagami
mesh_terms: D000143:Acids / Q000737:chemistry; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry; D001896:Boron Compounds / Q000737:chemistry; D002327:Cariostatic Agents / Q000737:chemistry*; D003188:Composite Resins / Q000737:chemistry; D003461:Crystallography; D001840:Dental Bonding; D003804:Dentin / Q000648:ultrastructure*; D017220:Dentin-Bonding Agents / Q000737:chemistry*; D004058:Diffusion; D006801:Humans; D017736:Ion-Selective Electrodes; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry; D008768:Methylmethacrylates / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D012969:Sodium Fluoride / Q000737:chemistry*; D012973:Sodium Hypochlorite / Q000737:chemistry; D013696:Temperature; D013997:Time Factors; D017001:Tooth Demineralization / Q000473:pathology; D014867:Water / Q000737:chemistry
chemical_list: D000143:Acids; D001896:Boron Compounds; D002327:Cariostatic Agents; C503075:Clearfil Protect Bond; D003188:Composite Resins; D017220:Dentin-Bonding Agents; D008689:Methacrylates; D008768:Methylmethacrylates; D014867:Water; D017438:Bisphenol A-Glycidyl Methacrylate; C005044:hydroxyethyl methacrylate; C069749:methacryloyloxydecyl dihydrogen phosphate; D012969:Sodium Fluoride; C049495:Super-bond; D012973:Sodium Hypochlorite