[Vesical tuberculosis after Bacillus Calmette-Guerin intravesical instillation therapy for bladder cancer].
An 82-year-old man who had undergone transurethral resection (TUR) for superficial bladder cancer (pT1 G3) in June and Luly 2011 received intravesical Bacillus Calmette-Guerin therapy (80 mg weekly for 6 weeks) in September 2011. Seven months later, a follow-up cystoscopy revealed a slowly growing torose lesion at the site of the previous TUR. The lesion was removed by TUR in June 2012. Pathological examination showed an inflammatory response with small granulomatous lesions. The specimen stained positive for TB DNA-RTPCR. Mycobacterium bovis was detected from the bladder specimen and urine. He was administered antituberculous agents, isoniazid 300 mg and rifampicin 450 mg daily, for 3 months. He is well with no recurrence of bladder carcinoma and urinary cultures were negative during the follow-up.
The Department of Urology, Yokohama City University, Japan.
Shinji
S
Ohtake
Kaoru
K
Kawaji
Noboru
N
Nakaigawa
Yoshiaki
Y
Inayama
Yoshinobu
Y
Kubota
D000283:Administration, Intravesical; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D009163:Mycobacterium bovis; D014401:Tuberculosis, Urogenital / Q000209:etiology*; D001745:Urinary Bladder Diseases / Q000209:etiology*; D001749:Urinary Bladder Neoplasms / Q000628:therapy*