Carbon nanotubes in hyperthermia therapy.
Thermal tumor ablation therapies are being developed with a variety of nanomaterials, including single- and multiwalled carbon nanotubes. Carbon nanotubes (CNTs) have attracted interest due to their potential for simultaneous imaging and therapy. In this review, we highlight in vivo applications of carbon nanotube-mediated thermal therapy (CNMTT) and examine the rationale for use of this treatment in recurrent tumors or those resistant to conventional cancer therapies. Additionally, we discuss strategies to localize and enhance the cancer selectivity of this treatment and briefly examine issues relating the toxicity and long term fate of CNTs.
Department of Cancer Biology, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.
Ravi
R
Singh
Suzy V
SV
Torti
D000818:Animals; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation / Q000379:methods*; D037742:Nanotubes, Carbon / Q000009:adverse effects / Q000737:chemistry*; D009364:Neoplasm Recurrence, Local; D009369:Neoplasms / Q000473:pathology / Q000628:therapy*; D013997:Time Factors
D037742:Nanotubes, Carbon
Cancer therapy; Carbon nanotubes; Multiwalled nanotubes; Photothermal therapy; Single-walled nanotubes