[Clinical effectiveness of metformin and ramipril combination in complex therapy of patients with metabolic syndrome].
6 monthly application of the combination of metformin with ramipril (1000 and 5 mg per day respectively) in complex treatment of metabolic syndrome (MS) leads to improvement of the clinical course of ischemic heart disease (decrease of quantity and duration of painful cardial attacks, depression of the functional class of an angina of exertion, decrease of displays of chronic heart failure), normalization of arterial pressure and decrease of an abdominal obesity which can be considered as prophylaxis of development of diabetes mellitus 2 types and its cardiovascular complications. Combination of metformin with ramipril in complex treatment of a MS is effective and safe option of therapy of MS.
L H
LH
Savchenko
E I
EI
Kaĭdasheva
L O
LO
Kutsenko
N L
NL
Kutsenko
I L
IL
Hordyns'ka
T V
TV
Mamontova
T M
TM
Markina
I P
IP
Kaĭdashev
D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure / Q000187:drug effects; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology; D004359:Drug Therapy, Combination; D006801:Humans; D024821:Metabolic Syndrome / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology; D008687:Metformin / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D017257:Ramipril / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
D001786:Blood Glucose; D008687:Metformin; D017257:Ramipril