Macrofinancing efficient remodeling of damaged muscle tissue.
In this issue of Cell Metabolism, Mounier et al. (2013) show that AMPKα1 is a crucial contributor to the regeneration of damaged muscle tissues, acting in macrophages at the nexus between proinflammatory debris removal and resolution of muscle tissue inflammation.
Bone-Muscle-Joint-Urology, Lilly Research Laboratories, Indianapolis, IN 46225, USA. krishnan_gary@lilly.com
Venkatesh
V
Krishnan
Benjamin C
BC
Yaden
D055372:AMP-Activated Protein Kinases / Q000378:metabolism*; D000818:Animals; D007249:Inflammation / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism*; D010587:Phagocytosis / Q000276:immunology*
C548179:Prkaa1 protein, mouse; D055372:AMP-Activated Protein Kinases