Oxidation of 2-arylindoles for synthesis of 2-arylbenzoxazinones with oxone as the sole oxidant.
A novel and efficient method for the oxidation of 2-arylindoles to synthesize 2-arylbenzoxazinones utilizing oxone as the sole oxidant has been developed. The reaction tolerates a wide range of functional groups and allows quick and atom-economical assembly of a variety of valuable 2-arylbenzoxazinones in high yields.
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University, Xi'an 710069, PR China.
Xiao-Li
XL
Lian
Hao
H
Lei
Xue-Jing
XJ
Quan
Zhi-Hui
ZH
Ren
Yao-Yu
YY
Wang
Zheng-Hui
ZH
Guan
D048588:Benzoxazines / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D016877:Oxidants / Q000737:chemistry*; D010084:Oxidation-Reduction; D013464:Sulfuric Acids / Q000737:chemistry*
D048588:Benzoxazines; D007211:Indoles; D016877:Oxidants; D013464:Sulfuric Acids; C048813:potassium peroxymonosulfuric acid