Carcinosarcoma in a white Rhinoceros (Ceratotherium simum simum).
In Rhinocerotidae, there are very few reports of tumors and no reports of a mixed tumor. This paper reports the case of a male 33-year-old southern white rhinoceros. Grossly, there were two masses in the coelomic cavity and solid nodules in the liver. Histologically, all tumors had a biphasic pattern that consisted of malignant epithelial cells (cytokeratin- and E-cadherin-positive) and non-epithelial cells (vimentin-positive) with cartilage. In this case, the prostate could not be identified, and instead, the largest tumor mass was present at that site. Furthermore, since structures regarded as the prostate duct remained in this tumor, we considered that this tumor was very likely to be of prostate gland origin. This case is the first report of carcinosarcoma in Rhinocerotidae.
Laboratory of Veterinary Pathology, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan.
Takuya
T
Suzuki
Tomoo
T
Kudo
Shigehisa
S
Kawakami
Yumi
Y
Une
D000818:Animals; D000836:Animals, Zoo; D002296:Carcinosarcoma / Q000473:pathology / Q000662:veterinary*; D017809:Fatal Outcome; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary / Q000662:veterinary*; D008297:Male; D010527:Perissodactyla; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000662:veterinary*