11α-Ethoxy-β-boswellic acid and nizwanone, a new boswellic acid derivative and a new triterpene, respectively, from Boswellia sacra.
A new boswellic acid derivative, 11α-ethoxy-β-boswellic acid (EBA; 1) and a new ursane-type triterpene, named nizwanone (2), were isolated from Omani frankincense Boswellia sacra Flueck. together with two known compounds papyriogenin B and rigidenol. The structures of 1 and 2 were elucidated by detailed spectroscopic analysis using (1) H- and (13) C-NMR, (1) H,(1) H-COSY, HMQC, HMBC, and HR-EI-MS techniques. The relative configurations of 1 and 2 were assigned by comparative analysis of the NMR spectral data with those of known analogs together with NOESY experiments. Structures of known compounds were identified by comparison with the reported data.
Department of Biological Sciences and Chemistry, University of Nizwa, P.O. Box 33, Postal Code 616, Birkat Al Mauz, Nizwa, Sultanate of Oman. aharrasi@unizwa.edu.om
Ahmed
A
Al-Harrasi
Liaqat
L
Ali
Najeeb
N
Ur Rehman
Javid
J
Hussain
Hidayat
H
Hussain
Ahmed
A
Al-Rawahi
Tania
T
Shamim Rizvi
D029743:Boswellia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012116:Resins, Plant / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
D012116:Resins, Plant; D014315:Triterpenes
Boswellia sacra; Nizwanone; Triterpenes; Ursanes; β-Boswellic acid, 11α-ethoxy-