[Spermatic cord seal-up injection for acute epididymitis: clinical observation of 56 cases].
OBJECTIVE
To investigate the clinical effect of spermatic cord seal-up injection on acute epididymitis and its mechanisms.


METHODS
A total of 120 cases of acute epididymitis were allocated to a trial group (n = 56), aged 18 - 78 (38.4 +/- 9.6) years, and a control group (n = 64), aged 14 -82 (41.3 +/- 7.2) years. The patients in the trial group were given seal-up injections of a mixture of lidocaine, gentamicin (or Amikacin) and dexamethasone into the spermatic cord, qd or bid, for 2 courses of 5 days each, with an interval of 3 to 5 days. Those in the control group were treated by intravenous drip of penicillin, qd, intramuscular injection of Streptomycin, bid, and oral medication of SMZCo (SMZ-TMP), bid, with the initial dose doubled. After less than 2 weeks of treatment, we compared the therapeutic effects between the two groups of patients.


RESULTS
In the trial group, 53.6% of the patients were basically cured, 37.5% obviously improved and 91.1% improved (total rate of effectiveness). The average treatment time for the improved cases was (9.2 +/- 0.5) d. In the control group, 40.6% of the patients were basically cured, 31.2% obviously improved and 71.8% improved (total rate of effectiveness). The average treatment time for the improved cases was (12.8 +/- 0.7) d. There were significant differences between the two groups in the total rate of effectiveness and the average treatment time for the improved cases (P < 0.05).


CONCLUSIONS
Spermatic cord seal-up injection for acute epididymitis deserves wide clinical application for its simple operation, good tolerance, short therapeutic course and high safety and efficacy.
Department of Urology, Jingzhou Third People's Hospital, Jingzhou, Hubei 434000, China. qiaoliang777@sina.com
Liang
L
Qiao
Zhi-Quan
ZQ
Liu
Jun
J
Xiang
Chen
C
Lin
Xiang-E
XE
Liu
Ying
Y
He
Cheng-Hao
CH
Yan
D000208:Acute Disease; D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004823:Epididymitis / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013085:Spermatic Cord; D055815:Young Adult