Sulfonic acid functionalized nano-γ-Al2O3: a new, efficient, and reusable catalyst for synthesis of 3-substituted-2H-1,4-benzothiazines.
A simple and efficient synthetic protocol has been developed for the synthesis of 3-substituted-2H-1,4-benzothiazines by using a novel sulfonic acid functionalized nano-γ-Al2O3 catalyst, devoid of corrosive acidic, and basic reagents. The developed method has the advantages of good to excellent yields, short reaction times, operational simplicity, and a recyclable catalyst. The catalyst can be prepared by a simple procedure from inexpensive and readily available nano-γ-Al2O3 and has been shown to be recoverable and reusable up to six cycles without any loss of activity.
Department of Medicinal Chemistry, Pharmacy College of Xinxiang Medical University, Xinxiang 453003, China. linweilin1977@163.com
Wei Lin
WL
Li
Shuan Bao
SB
Tian
Feng
F
Zhu
D000537:Aluminum Oxide / Q000737:chemistry*; D002384:Catalysis; D046529:Microscopy, Electron, Transmission; D036103:Nanotechnology; D017550:Spectroscopy, Fourier Transform Infrared; D013451:Sulfonic Acids / Q000737:chemistry*; D013843:Thiazines / Q000737:chemistry*
D013451:Sulfonic Acids; D013843:Thiazines; D000537:Aluminum Oxide