[Acute myocardial infarction in women. Initial characteristics, management and early outcome. The FAST-MI registry].
OBJECTIVE
To assess gender differences in characteristics, management, and hospital outcomes in patients participating in the French FAST-MI 2010 registry.


METHODS
Three thousand and seventy-nine patients hospitalised for ST-elevation (STEMI) or non-ST-elevation (NSTEMI) myocardial infarction in 213 French centres during a 1-month period at the end of 2010.


RESULTS
Women account for 27% of the population and more frequently present with NSTEMI. They are 9 years older than men on average, although 25% of women with STEMI are less than 60 years of age. Management of STEMI is similar, after adjustment for baseline characteristics. However, fewer women are treated with primary percutaneous coronary angioplasty. In NSTEMI, although use of coronary angiography is similar, fewer women get treated with angioplasty. Most medications are used in a similar way in men and women, except thienopyridines, with fewer women receive prasugrel. After adjustment, in-hospital mortality is similar for men and women.


CONCLUSIONS
Myocardial infarction is not specific to men: one out of four patients admitted for myocardial infarction is a woman. Initial management is rather similar for men and women, after taking into account differences in baseline characteristics. Percutaneous coronary angioplasty, however, remains less frequently used in women. In-hospital complications have become rarer and do not differ according to sex.
Service de pharmacologie clinique, URC-EST, hôpital Saint-Antoine, AP-HP, université Pierre-et-Marie-Curie-Paris-06, 75012 Paris, France.
T
T
Simon
E
E
Puymirat
V
V
Lucke
N
N
Bouabdallaoui
T
T
Lognoné
N
N
Aissaoui
S
S
Cohen
G
G
Ashrafpoor
G
G
Roul
B
B
Jouve
G
G
Levy
S
S
Charpentier
G
G
Grollier
J
J
Ferrières
N
N
Danchin
D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary / Q000706:statistics & numerical data*; D017023:Coronary Angiography; D004562:Electrocardiography; D005260:Female; D005602:France / Q000453:epidemiology; D006329:Heart Conduction System / Q000503:physiopathology*; D017052:Hospital Mortality; D006801:Humans; D007297:Inpatients / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D012042:Registries / Q000706:statistics & numerical data; D012307:Risk Factors; D017678:Sex Distribution; D013997:Time Factors; D016896:Treatment Outcome
Infarctus; Management; Mortalité; Myocardial infarction; Outcomes; Prise en charge; Sex; Sexe