[Adrenal carcinoma induced hypoglycemia].
Adrenal carcinoma is a rare malignancy of poor prognosis. The most common clinical presentation is secondary to hormone production, while the development of symptomatic hypoglycemia is exceptional. We report the case of a 37 year old-woman admitted to hospital with severe hypoglycemia, hypertension, hypokalemia and amenorrhea. In the laboratory we found hypoglycemia, with low insulin levels, and androgen levels in tumor range. CT of abdomen and pelvis showed a heterogeneous lesion of solid appearance without a cleavage plane relative to liver parenchyma, and intense contrast enhancement. Retroperitoneal mass was removed, and the patient evolved without complications, blood glucose and potassium were normalized, blood pressure stabilized and menstrual cycles recovered.
Servicio de Endocrinología, Complejo Médico Churruca-Visca, Buenos Aires, Argentina. jimesoutelo@arnet.com.ar
Jimena
J
Soutelo
Melina
M
Saban
Florencia
F
Borghi Torzillo
Ruben
R
Lutfi
Mariela
M
Leal Reyna
D000306:Adrenal Cortex Neoplasms / Q000097:blood / Q000150:complications*; D018268:Adrenocortical Carcinoma / Q000097:blood / Q000150:complications*; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology*; D007328:Insulin / Q000097:blood; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D007335:Insulin-Like Growth Factor II / Q000032:analysis
D001786:Blood Glucose; D007328:Insulin; D007334:Insulin-Like Growth Factor I; D007335:Insulin-Like Growth Factor II
adrenal carcinoma; hypoglycemia; insulin-like growth factor II (IGFII)