Anterior and pan-endophthalmitis caused by Candida albicans and Aspergillus fumigatus: report of two cases.
We report two posttraumatic fungal endophthalmitis cases with anterior and entire segment involvement caused, respectively, by Candida albicans and Aspergillus fumigatus. The anterior endophthalmitis induced by C. albicans presented multifocal lesions with hyphael structures in anterior chamber, but without involvement of posterior vitreous. The pan-endophthalmitis caused by A. fumigatus displayed significant hypopyon and vitritis. Treatment strategies are anterior chamber cleaning for anterior endophthalmitis and vitrectomy for pan-endophthalmitis, excepting systemic and topical antifungal drug applications including intravitreal injection for both types of endophthalmitis. There is a much better outcome in the case with anterior segment involvement than that with entire segment involvement. This case report provides evidence that the different types of posttraumatic fungal endophthalmitis related to different fungal infections indeed existed and should be managed with different strategies.
Eye Hospital of Wenzhou Medical College, Wenzhou, Zhejiang, China.
Anan
A
Wang
Jianxiong
J
Cao
Shufang
S
Hu
Zhenquan
Z
Zhao
Mingling
M
Wang
Tianlin
T
Xiao
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D002176:Candida albicans / Q000302:isolation & purification*; D002177:Candidiasis / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D003646:Debridement; D009877:Endophthalmitis / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D005260:Female; D006801:Humans; D014821:Vitrectomy; D014946:Wound Infection / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology; D014947:Wounds and Injuries / Q000150:complications
D000935:Antifungal Agents