Correlation between spectral-domain optical coherence tomography and autofluorescence findings in sclerochoroidal calcification.
OBJECTIVE
The purpose of this article is to report the correlation between spectral domain-optical coherence tomography and autofluorescence findings in 3 consecutive cases with sclerochoroidal calcification.


METHODS
Observational case series.


METHODS
The study involved 3 patients with bilateral sclerochoroidal calcification.


METHODS
B-scan ultrasonography, spectral domain-optical coherence tomography, and autofluorescence were performed in each eye. The choroidal vascular thickness and autofluorescence patterns of the calcified plaques were evaluated with spectral domain-optical coherence tomography and autofluorescence, respectively.


RESULTS
An important variation of choroidal vascular thickness overlying sclerochoroidal calcification was observed in spectral domain-optical coherence tomography. Autofluorescence showed 2 patterns of autofluorescence closely correlated with changes in choroidal vascular thickness. In those zones where the thicknesses of choriocapillaris complex were reduced, a hyperautofluorescence pattern was observed in autofluorescence. The hypoautofluorescence pattern was observed in outpouching zone of retinal pigment epithelium-choriocapillaris complex seen in spectral domain-optical coherence tomography. The hypoautofluorescence pattern was closely correlated with remarkable reduction of the choriocapillaris complex. There were no significant differences between the patterns of autofluorescence except the extension.


CONCLUSIONS
Spectral domain-optical coherence tomography and autofluorescence are noninvasive complementary imaging studies that may help to improve our knowledge about sclerochoroidal calcification. Characteristic patterns of autofluorescence were closely correlated with spectral domain-optical coherence tomography findings. More patients need to be evaluated with both complementary studies to establish conclusions related with these findings.
Department of Ophthalmology, Section of Retina and Ocular Oncology, Hospital Universitari de Bellvitge, Barcelona, Spain.
José María
JM
Caminal-Mitjana
Noel
N
Padrón-Pérez
Luis
L
Arias-Barquet
Marcos Javier
MJ
Rubio-Caso
Jaume
J
Català-Mora
D000328:Adult; D000368:Aged; D002114:Calcinosis / Q000175:diagnosis*; D002829:Choroid / Q000473:pathology; D015862:Choroid Diseases / Q000175:diagnosis*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D015422:Scleral Diseases / Q000175:diagnosis*; D013223:Statistics as Topic; D041623:Tomography, Optical Coherence; D014792:Visual Acuity