Diversity and evolution of ABC proteins in basidiomycetes.
ABC proteins constitute one of the largest families of proteins. They are implicated in wide variety of cellular processes ranging from ribosome biogenesis to multidrug resistance. With the advance of fungal genomics, the number of known fungal ABC proteins increases rapidly but the information on their biological functions remains scarce. In this work we extended the previous analysis of fungal ABC proteins to include recently sequenced species of basidiomycetes. We performed an identification and initial cataloging of ABC proteins from 23 fungal species representing 10 orders within class Agaricomycotina. We identified more than 1000 genes coding for ABC proteins. Comparison of sets of ABC proteins present in basidiomycetes and ascomycetes revealed the existence of two groups of ABC proteins specific for basidiomycetes. Results of survey should contribute to the better understanding of evolution of ABC proteins in fungi and support further experimental work on their characterization.
Department of Forest Sciences, P.O. Box 27, Latokartanonkaari 7, 00014 University of Helsinki, Helsinki, Finland.
Andriy
A
Kovalchuk
Yong-Hwan
YH
Lee
Fred O
FO
Asiegbu
D018528:ATP-Binding Cassette Transporters / Q000737:chemistry / Q000235:genetics*; D001487:Basidiomycota / Q000737:chemistry / Q000145:classification / Q000235:genetics*; D019143:Evolution, Molecular; D005656:Fungal Proteins / Q000737:chemistry / Q000235:genetics*; D014644:Genetic Variation; D016681:Genome, Fungal; D005810:Multigene Family; D017434:Protein Structure, Tertiary
D018528:ATP-Binding Cassette Transporters; D005656:Fungal Proteins
ABC transporters; fungi; multidrug transporters; protein family evolution