Pivoting the plant immune system from dissection to deployment.
Diverse and rapidly evolving pathogens cause plant diseases and epidemics that threaten crop yield and food security around the world. Research over the last 25 years has led to an increasingly clear conceptual understanding of the molecular components of the plant immune system. Combined with ever-cheaper DNA-sequencing technology and the rich diversity of germ plasm manipulated for over a century by plant breeders, we now have the means to begin development of durable (long-lasting) disease resistance beyond the limits imposed by conventional breeding and in a manner that will replace costly and unsustainable chemical controls.
Department of Biology, University of North Carolina, Chapel Hill, NC 27599, USA. dangl@email.unc.edu
Jeffery L
JL
Dangl
Diana M
DM
Horvath
Brian J
BJ
Staskawicz
D000483:Alleles; D001947:Breeding; D018556:Crops, Agricultural / Q000235:genetics / Q000276:immunology* / Q000382:microbiology / Q000469:parasitology; D060467:Disease Resistance / Q000235:genetics; D017343:Genes, Plant; D010935:Plant Diseases / Q000276:immunology*; D057865:Plant Immunity / Q000235:genetics; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism; D010944:Plants / Q000235:genetics / Q000276:immunology* / Q000382:microbiology / Q000469:parasitology; D030821:Plants, Genetically Modified; D011639:Public Opinion; D051192:Receptors, Pattern Recognition / Q000235:genetics / Q000378:metabolism
D010940:Plant Proteins; D051192:Receptors, Pattern Recognition