Chronic cough management: dealing with a sensation of irritation in the throat.
Among the various types of laryngeal paraesthesia suffered by chronic cough patients, we often encounter 'a sensation of irritation in the throat (SIT)'. Our study indicated that capsaicin cough threshold was significantly (P < 0.05) lower in the SIT-positive group (13.9 μmol/L) than in the SIT-negative group (49.6 μmol/L). The establishment of treatment strategies for SIT would be advantageous for treating chronic cough patients suffering from this laryngeal sensation.
The Division of Pulmonary Medicine, Ishikawa-ken Saiseikai Kanazawa Hospital, Kanazawa, Japan.
Haruhiko
H
Ogawa
Masaki
M
Fujimura
Noriyuki
N
Ohkura
Koichi
K
Makimura
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001985:Bronchial Provocation Tests; D002211:Capsaicin / Q000009:adverse effects; D002908:Chronic Disease; D003371:Cough / Q000175:diagnosis / Q000628:therapy*; D019468:Disease Management; D005260:Female; D006801:Humans; D007818:Laryngeal Diseases / Q000150:complications / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010292:Paresthesia / Q000150:complications / Q000503:physiopathology; D010614:Pharynx / Q000503:physiopathology*; D012189:Retrospective Studies; D012677:Sensation / Q000502:physiology*
D002211:Capsaicin
cough hypersensitivity; cough suppression therapy; laryngeal sensation; sensation of irritation in the throat; sensation of mucus in the throat