[Analysis of alkaloids in Zanthoxylum nitidum by HPLC-DAD/ESI-Q-TOF-MS].
The alkaloids in Zanthoxylum nitidum were identified by HPLC-DAD/ESI-Q-TOF-MS. Separation was performed on a Hanbon C18 column with acetonitrile (with 0.1% formic acid) and water(with 0.1% formic acid) as mobile phase. Based on the high-resolution mass information, MS/MS fragmentation behaviors and chemical components from literatures, 48 components were identified or tentatively characterized including 6 new compounds. This work could be useful for the quality control and further studies of the plant.
Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China. jcp841006@yahoo.com.cn
Chang-Ping
CP
Jia
Xue-Li
XL
Huang
Yun
Y
Li
Fang
F
Feng
D000470:Alkaloids / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D021241:Spectrometry, Mass, Electrospray Ionization; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D032106:Zanthoxylum / Q000737:chemistry*
D000470:Alkaloids