Comparison of poliglecaprone-25 and polyglactin-910 in cutaneous surgery.
BACKGROUND
Few clinical studies have compared deep absorbable sutures. Poliglecaprone-25 and polyglactin-910 are two of the most commonly used absorbable sutures in cutaneous surgery.


OBJECTIVE
To compare the rate of suture extrusion, degree of lumpiness, and appearance of scars from wounds closed with poliglecaprone-25 and polyglactin-910.


METHODS
Poliglecaprone-25 or polyglactin-910 was used for closure of the deep part of Mohs defects. The number of extruded sutures and the number of lumps were recorded at each follow-up visit. Photographs of 1-week and 3-month postoperative scars were rated on a visual analogue scale.


RESULTS
One hundred forty patients completed the study. There was a statistically significant difference in the percentage of extruded sutures between poliglecaprone-25 (3.1%) and polyglactin-910 (11.4%) (p < .01). There was not a statistically significant difference in the percentage of lumps (both 22%) or overall appearance of scars at 1 week or 3 months.


CONCLUSIONS
Poliglecaprone-25 resulted in significantly less extruded sutures than did polyglactin-910, although both resulted in the same degree of lumpiness and similar-appearing scars at 1 week and 3 months.
Pennsylvania Centre for Dermatology, Philadelphia, Pennsylvania.
Thomas
T
Regan
Naomi
N
Lawrence
D000368:Aged; D002921:Cicatrix / Q000209:etiology; D004146:Dioxanes / Q000009:adverse effects; D004423:Ear; D005260:Female; D006801:Humans; D008297:Male; D015580:Mohs Surgery; D009666:Nose; D011091:Polyesters / Q000009:adverse effects; D011098:Polyglactin 910 / Q000009:adverse effects; D013537:Sutures / Q000009:adverse effects
D004146:Dioxanes; D011091:Polyesters; D011098:Polyglactin 910; C095495:glycolide E-caprolactone copolymer