Feasibility trial of a Spanish-language multimedia educational intervention.
BACKGROUND
Hispanic cancer patients are underrepresented in clinical trials; research suggests lack of knowledge and language barriers contribute to low accrual. Multimedia materials offer advantages to Hispanic populations because they have high acceptability, are easy to disseminate, and can be viewed with family.


OBJECTIVE
Hispanic cancer patients and caregivers participated in focus groups to aid in developing a Spanish-language multimedia intervention to educate Hispanic cancer patients about clinical trials. We explored the feasibility of delivering the intervention in medical oncology clinics.


METHODS
A total of 35 patients were randomized to either the multimedia intervention group (n = 18) or a control group (n = 17) who were asked to read the National Cancer Institute's Spanish-language clinical trials brochure. Self-reported data on knowledge about and attitudes toward clinical trials, self-efficacy for participating in a clinical trial, intention to participate in a clinical trial if asked, and receptivity to information about a clinical trial were collected at baseline and 10 days later.


RESULTS
Delivery of the multimedia presentation in oncology clinics was feasible. The intervention group had more knowledge about clinical trials at follow-up than the control group; scores for intention to participate in a clinical trial by participants in the intervention group increased from 3.8 to 4.0 of a possible 5, but declined in the control group from 4.5 to 4.1. No statistically significant difference was detected between groups in scores for attitudes or self-efficacy for making a decision to participate in a clinical trial.


CONCLUSIONS
Our sample size was inadequate to identify differences between the informational methods. Although all patients were asked about their willingness to participate in a clinical trial, this decision was hypothetical. In addition, the study was conducted with a sample of Spanish-speaking Hispanic cancer patients at a comprehensive cancer center in Florida. Thus, the results may not generalize to other Hispanic populations.


CONCLUSIONS
In the pilot project, we demonstrated the feasibility of delivering multimedia information to patients in medical oncology clinics. Because delivery in a clinical setting was found to be feasible, a larger study should be conducted to evaluate the efficacy of the multimedia intervention with respect to promoting accrual of Hispanic patients to clinical trials.
aDepartment of Psychology, San Diego State University, San Diego, CA, USA.
Kristen J
KJ
Wells
Jessica
J
McIntyre
Luis E
LE
Gonzalez
Ji-Hyun
JH
Lee
Kate J
KJ
Fisher
Paul B
PB
Jacobsen
Cathy
C
Meade
Teresita
T
Muñoz-Antonia
Gwendolyn P
GP
Quinn
D000328:Adult; D000368:Aged; D002173:Cancer Care Facilities; D002986:Clinical Trials as Topic / Q000379:methods*; D005260:Female; D017144:Focus Groups; D006266:Health Education / Q000379:methods*; D007722:Health Knowledge, Attitudes, Practice; D006630:Hispanic or Latino; D006801:Humans; D033182:Intention; D007802:Language; D008297:Male; D008875:Middle Aged; D019212:Multimedia; D009369:Neoplasms / Q000208:ethnology* / Q000523:psychology / Q000628:therapy; D035842:Research Subjects / Q000523:psychology*; D020377:Self Efficacy; D012959:Socioeconomic Factors