[Influence of carbapenem selection pressure on bacterial resistance].
As a result of high resistance of bacterial pathogens to broad-spectrum penicillins and cephalosporins, carbapenems have been increa-singly used recently. The presented study aimed at analyzing the association between carbapenem consumption and resistance of selected Gramnegative pathogens to meropenem. Using linear regression analysis, a statistically significant association was found between carbapenem consumption and resistance of Pseudomonas aeruginosa.
Department of Microbiogy, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Czech Republic. milan.kolar@fnol.cz
Milan
M
Kolář
Miroslava
M
Htoutou Sedláková
Hana
H
Suchánková
Vojtěch
V
Hanulík
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006801:Humans; D000077731:Meropenem; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013845:Thienamycins / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D013845:Thienamycins; D000077731:Meropenem