Diversity of secondary metabolites from marine Bacillus species: chemistry and biological activity.
Marine Bacillus species produce versatile secondary metabolites including lipopeptides, polypeptides, macrolactones, fatty acids, polyketides, and isocoumarins. These structurally diverse compounds exhibit a wide range of biological activities, such as antimicrobial, anticancer, and antialgal activities. Some marine Bacillus strains can detoxify heavy metals through reduction processes and have the ability to produce carotenoids. The present article reviews the chemistry and biological activities of secondary metabolites from marine isolates. Side by side, the potential for application of these novel natural products from marine Bacillus strains as drugs, pesticides, carotenoids, and tools for the bioremediation of heavy metal toxicity are also discussed.
School of Science and Technology, Bangladesh Open University, Board Bazar, Gazipur 1705, Bangladesh. mondol_sst@yahoo.com
Muhammad Abdul Mojid
MA
Mondol
Hee Jae
HJ
Shin
Mohammad Tofazzal
MT
Islam
D000818:Animals; D001407:Bacillus / Q000378:metabolism*; D001673:Biodegradation, Environmental / Q000187:drug effects; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D015195:Drug Design; D006801:Humans; D019216:Metals, Heavy / Q000633:toxicity
D001688:Biological Products; D019216:Metals, Heavy