Arylations of substituted enamides by aryl iodides: regio- and stereoselective synthesis of (Z)-β-amido-β-arylacrylates.
Arylations of substituted enamides by aryl iodides were achieved for the first time via an unusual PdCl2(COD)/Ag3PO4 catalytic system. A broad range of (Z)-β-amido-β-arylacrylates were prepared regio- and stereoselectively in a highly efficient manner.
School of Chemical Science and Technology, Yunnan University, Kunming, Yunnan, 650091, PR China.
Quan
Q
Gou
Bin
B
Deng
Hongbin
H
Zhang
Jun
J
Qin