Microbial sulfation of 8-prenylnaringenin.
Out of 24 fungal strains tested for their ability to transform 8-prenylnaringenin, Syncephalastrum racemosum was found to convert this phytoestrogen to a sulfate derivative. The conjugation with sulfuric acid observed in this study is paralleled in mammals indicating that microbes can be used to mimic mammalian metabolism.
Department of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. agnieszka.bartmanska@up.wroc.pl
Agnieszka
A
Bartmańska
Tomasz
T
Tronina
Ewa
E
Huszcza
D002851:Chromatography, High Pressure Liquid; D044950:Flavanones / Q000378:metabolism*; D027582:Humulus / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D009090:Mucorales / Q000378:metabolism*; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet; D013431:Sulfates / Q000378:metabolism*
C119737:8-prenylnaringenin; D044950:Flavanones; D013431:Sulfates