Outcomes of cataract surgery in ocular cicatricial pemphigoid.
OBJECTIVE
To report the outcomes of cataract surgery in ocular cicatricial pemphigoid (OCP).


METHODS
L. V. Prasad Eye Institute, Hyderabad, India.


METHODS
Retrospective, interventional case series.


METHODS
Patients diagnosed with OCP who had undergone cataract surgery were included. Staging of disease, type of surgery, pre- and postoperative best-corrected visual acuity (BCVA), and number and duration of topical and systemic medications were recorded. Complications and any exacerbation or worsening of disease were noted.


RESULTS
Nine eyes of 7 patients (3 male, 4 female) were included in the study, with mean age of 60.44 ± 2.6 years (range 56-64 years). Follow-up ranged from 6 months to 10 years (mean 52.9 ± 46.25 months). Surgery performed was extracapsular cataract extraction with posterior chamber intraocular lens implantation (n = 5) or phacoemulsification with posterior chamber intraocular lens implantation (n = 4). Best-corrected visual acuity improved by more than 2 lines in 6 of 9 (66.67%) eyes, which remained stable till the last follow-up. Three eyes had no visual improvement due to corneal scar in 2 patients and preexisting posterior staphyloma in 1 eye. Disease progression was noted in 2 of 9 operated eyes by one stage at the end of 1 year.


CONCLUSIONS
In this series, cataract surgery could be safely performed with no major intra- or postoperative complications. While the surgical intervention itself was not associated with acute exacerbations of inflammation, progression of disease was noted in some cases over time. In spite of ongoing disease, cataract surgery in OCP was associated with stable visual outcomes.
Cornea and Anterior Segment Service, L.V. Prasad Eye Institute, Kallam Anji Reddy Campus , Hyderabad , India.
Charuta J
CJ
Puranik
Somasheila I
SI
Murthy
Mukesh
M
Taneja
Virender S
VS
Sangwan
D001706:Biopsy; D002386:Cataract / Q000175:diagnosis / Q000209:etiology*; D002387:Cataract Extraction / Q000379:methods*; D003228:Conjunctiva / Q000473:pathology; D018450:Disease Progression; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D005544:Forecasting; D006801:Humans; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D010390:Pemphigoid, Benign Mucous Membrane / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D016896:Treatment Outcome; D014792:Visual Acuity