Palladium-catalyzed intermolecular asymmetric allylic dearomatization reaction of naphthol derivatives.
Baring all: The title reaction provides β-naphthalenones bearing an all-carbon quaternary center in good to excellent yields, as well as excellent chemo- and enantioselectivity.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032 (China) http://shuliyou.sioc.ac.cn/
Chun-Xiang
CX
Zhuo
Shu-Li
SL
You
allylic dearomatization; arenes; asymmetric catalysis; palladium; synthetic methods