Myxoid lipoblastoma.
A rapidly growing soft tissue mass in the axilla of an infant raises the suspicion of a lipoblastoma or a liposarcoma. Excisional/incisional biopsy is vital in confirming the diagnosis and hence avoiding aggressive extirpation. This case report highlights the role of histopathology and immunohistochemistry as the gold standard in differentiating a lipoblastoma from a liposarcoma. In some cases where the histopathology is inconclusive, genetic rearrangement of the PLAG1 (pleomorphic adenoma gene 1) oncogene on chromosome 8q12 helps in confirming the diagnosis of lipoblastoma.
Department of Pediatric Surgery, Lilavati Hospital and Research Centre, Mumbai, India. jankrish.doc@gmail.com
Janani
J
Krishnan
Varun
V
Hathiramani
Meenal
M
Hastak
Rajeev G
RG
Redkar
D001365:Axilla / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D062689:Lipoblastoma / Q000175:diagnosis* / Q000473:pathology; D018208:Liposarcoma, Myxoid / Q000175:diagnosis* / Q000473:pathology