Is the taste of fat regulated?
Over the last decade, converging data have been accumulated both in rodents and humans, supporting the existence of a sixth taste modality devoted to the perception of dietary lipids. It is well known that the sense of taste is determinant for the food choice and that the overconsumption of highly palatable energy-dense foods contributes to the current obesity epidemic. Thus, an important issue in terms of Public Health is to understand the mechanisms by which the oro-sensory perception of fat is regulated. An overview of our current knowledge in this field of investigations is proposed in this mini-review.
Physiologie de la Nutrition et Toxicologie (NUTox), UMR U866 INSERM/Université de Bourgogne/AgroSup Dijon, AgroSup Dijon, 1, Esplanade Erasme, F-21000 Dijon, France.
Patricia
P
Passilly-Degrace
Michael
M
Chevrot
Arnaud
A
Bernard
Déborah
D
Ancel
Céline
C
Martin
Philippe
P
Besnard
D052436:Adipose Tissue, White / Q000378:metabolism; D000818:Animals; D004041:Dietary Fats / Q000378:metabolism*; D025461:Feedback, Physiological; D005247:Feeding Behavior; D006801:Humans; D009765:Obesity / Q000378:metabolism* / Q000503:physiopathology; D013649:Taste; D013650:Taste Buds / Q000502:physiology
D004041:Dietary Fats
AEA; CCK; CD36; CVP; DIO; Eating behavior; G protein-coupled receptors; GLP-1; GLP-1 receptor; GPCR; Glp1-r; Gustation; LCFA; NPY; NST; Obesity; PPY; PYY; TRC; VIP; cholecystokinin; circumvallate papillae; diet-induced obesity; endocannabinoid anandamide; glucagon-like peptide-1; long-chain fatty acids; neuropeptide Y; nucleus of solitary tract; pancreatic polypeptide; peptide YY; taste receptor cells; vasoactive intestinal peptide