Vaginal myofibroblastoma with prostatic glands: is there an association with tamoxifen use? A case report.
BACKGROUND
Both ectopic prostate tissue in the female genital tract and vaginal myofibroblastoma have rarely been reported in the literature. Tamoxifen use has been associated with the development of vaginal myofibroblastoma.


METHODS
A 76-year-old, multiparous woman who had taken tamoxifen for breast cancer presented with postmenopausal bleeding and a vaginal mass. Endometrial work-up revealed a benign polyp, and the polypoid tumor in the vagina was found to be a myofibroblastoma harboring ectopic prostatic glands.


CONCLUSIONS
To our knowledge this is the first case of these two rare pathologic entities occurring together. Of note, this patient also had a history of tamoxifen therapy, like some of the previous patients with vaginal myofibroblastoma.
Department of Obstetrics and Gynecology, Tufts University School of Medicine, Baystate Medical Center, 759 Chestnut Street, S-1681, Springfield, MA 01199, USA.
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D000368:Aged; D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy; D002828:Choristoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D009379:Neoplasms, Muscle Tissue / Q000473:pathology*; D011467:Prostate; D013629:Tamoxifen / Q000009:adverse effects*; D014625:Vaginal Neoplasms / Q000473:pathology*
D018931:Antineoplastic Agents, Hormonal; D013629:Tamoxifen