Comparison of microwave-assisted and conventional extraction of mangiferin from mango (Mangifera indica L.) leaves.
Mangiferin is the main bioactive component in mango leaves, which possesses anti-inflammatory, antioxidative, antidiabetic, immunomodulatory, and antitumor activities. In the present study, a microwave-assisted extraction method was developed for the extraction of mangiferin from mango leaves. Some parameters such as ethanol concentration, liquid-to-solid ratio, microwave power, and extraction time were optimized by single-factor experiments and response surface methodology. The optimal extraction conditions were 45% ethanol, liquid-to-solid ratio of 30:1 (mL/g), and extraction time of 123 s under microwave irradiation of 474 W. Under optimal conditions, the yield of mangiferin was 36.10 ± 0.72 mg/g, significantly higher than that of conventional extraction. The results obtained are beneficial for the full utilization of mango leaves and also indicate that microwave-assisted extraction is a very useful method for extracting mangiferin from plant materials.
Department of Nutrition and Food Hygiene, School of Public Health, Guangdong Medical College, Dongguan, China.
Tangbin
T
Zou
Hongfu
H
Wu
Huawen
H
Li
Qing
Q
Jia
Gang
G
Song
D005591:Chemical Fractionation / Q000295:instrumentation / Q000379:methods*; D031022:Mangifera / Q000737:chemistry*; D008872:Microwaves; D010936:Plant Extracts / Q000302:isolation & purification*; D018515:Plant Leaves / Q000737:chemistry*; D044004:Xanthones / Q000302:isolation & purification*
D010936:Plant Extracts; D044004:Xanthones; C013592:mangiferin
Mangiferin; Mango leaves; Microwave-assisted extraction; Response surface methodology