Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis.
The amphiphilic block copolymer, composed of hydrophilic dextran sulfate as the targeting ligand and hydrophobic polycaprolactone as the hydrophobic segment, was prepared via click chemistry to develop self-assembled nanoparticles for targeting rheumatoid arthritis.
Department of Chemical Engineering, Kyung Hee University, Gyeonggi-do 449-701, Republic of Korea.
Seol-Hee
SH
Kim
Jong-Ho
JH
Kim
Dong Gil
DG
You
Gurusamy
G
Saravanakumar
Hong Yeol
HY
Yoon
Ki Young
KY
Choi
Thavasyappan
T
Thambi
V G
VG
Deepagan
Dong-Gyu
DG
Jo
Jae Hyung
JH
Park
D000818:Animals; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D057930:Click Chemistry; D016264:Dextran Sulfate / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D051379:Mice; D058990:Molecular Targeted Therapy; D053758:Nanoparticles / Q000737:chemistry*; D011091:Polyesters / Q000737:chemistry
D004337:Drug Carriers; D011091:Polyesters; C016240:polycaprolactone; D016264:Dextran Sulfate