Acute late-onset encephalopathy after radiotherapy: an unusual life-threatening complication.
Unusual late-onset complications of brain irradiation, characterized by reversible neurologic focal signs, seizures, and MRI alterations, have recently been reported and classified as stroke-like migraine attacks after radiation therapy (SMART)(1) and peri-ictal pseudoprogression (PIPG).(2.)
From C. Mondino National Institute of Neurology Foundation (A.L.D., G.B., P.V., C.A.G., M.C., S.B., L.D., E.M.), IRCCS, Pavia, Italy; Neuroscience Consortium (G.B., L.D.), University of Pavia, Monza Policlinico and Pavia Mondino, Italy; Department of Neuro-oncology (F.D.), Hospices Civils de Lyon, Lyon Neuroscience Research Center INSERM U1028/CNRS UMR 5292, Université Claude Bernard Lyon, France; Department of Neuroscience (M.C., S.B.), University of Pavia, Italy; Bone Marrow Transplant Unit (A.A.C.), Department of Hematology Oncology, Foundation IRCCS, Policlinico San Matteo, Pavia, Italy; C.O.U. of Diagnostic Radiology and Interventional Radiology and Neuroradiology (A. Simoncelli), IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; Department of Neurology (M.C.B., B.G.), Ospedale Ca' Foncello, Treviso, Italy; Neuro-oncology Unit (P.G., A. Silvani), Neurological Institute C. Besta, Milan, Italy; and SC Neurologia (A. Salmaggi), Ospedale A. Manzoni, Lecco, Italy.
Anna Luisa
AL
Di Stefano
Giulia
G
Berzero
Paolo
P
Vitali
Carlo Andrea
CA
Galimberti
Francois
F
Ducray
Mauro
M
Ceroni
Stefano
S
Bastianello
Anna Amelia
AA
Colombo
Anna
A
Simoncelli
Marta Claudia
MC
Brunelli
Bruno
B
Giometto
Luca
L
Diamanti
Paola
P
Gaviani
Andrea
A
Salmaggi
Antonio
A
Silvani
Enrico
E
Marchioni
D000293:Adolescent; D000328:Adult; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D055815:Young Adult