Prediction of coronary risk by SYNTAX and derived scores: synergy between percutaneous coronary intervention with taxus and cardiac surgery.
The introduction of the SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery) score has prompted a renewed interest for angiographic risk stratification in patients undergoing percutaneous coronary intervention. Syntax score is based on qualitative and quantitative characterization of coronary artery disease by including 11 angiographic variables that take into consideration lesion location and characteristics. Thus far, this score has been shown to be an effective tool to risk-stratify patients with complex coronary artery disease undergoing percutaneous coronary intervention in the landmark SYNTAX trial, as well as in other clinical settings. This review provides an overview of its current applications, including its integration with other nonangiographic clinical scores, and explores future applications of the SYNTAX and derived scores.
Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York.
Mayank
M
Yadav
Istituto di Cardiologia, University of Bologna, Bologna, Italy.
Tullio
T
Palmerini
Hospital Israelita Albert Einstein and Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.
Adriano
A
Caixeta
Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York.
Mahesh V
MV
Madhavan
Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York.
Elias
E
Sanidas
Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York.
Ajay J
AJ
Kirtane
Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York.
Gregg W
GW
Stone
Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York; Hôpital du Sacré-Coeur de Montréal, Université de Montréal, Montréal, Québec, Canada. Electronic address: pg2295@columbia.edu.
Philippe
P
Généreux
D006348:Cardiac Surgical Procedures / Q000379:methods*; D003327:Coronary Disease / Q000175:diagnosis / Q000601:surgery*; D054855:Drug-Eluting Stents; D006801:Humans; D062645:Percutaneous Coronary Intervention / Q000379:methods*; D010936:Plant Extracts / Q000494:pharmacology*; D012720:Severity of Illness Index; D020946:Taxus
D010936:Plant Extracts
CABG; CAD; CSS; FFR; FSS; GRC; LM; MACCE; MACE; MI; PCI; SS; SYNTAX score; TVR; clinical SYNTAX score; coronary artery bypass graft; coronary artery disease; coronary risk stratification; fractional flow reserve; functional SYNTAX score; global risk classification; left main; major adverse cardiac event(s); major adverse cardiovascular and cerebrovascular event(s); myocardial infarction; percutaneous coronary intervention; rSS; residual SYNTAX score; risk score; target vessel revascularization