Focused fluorescent probe library for metal cations and biological anions.
A focused fluorescent probe library for metal cations was developed by combining metal chelators and picolinium/quinolinium moieties as combinatorial blocks connected through a styryl group. Furthermore, metal complexes derived from metal chelators having high binding affinities for metal cations were used to construct a focused probe library for phosphorylated biomolecules. More than 250 fluorescent probes were screened for identifying an ultraselective probe for dTTP.
Department of Chemistry, Seoul National University , Seoul 151-747, Korea.
Hyun-Woo
HW
Rhee
Sang Wook
SW
Lee
Jun-Seok
JS
Lee
Young-Tae
YT
Chang
Jong-In
JI
Hong
D000838:Anions / Q000032:analysis; D002412:Cations / Q000032:analysis; D002614:Chelating Agents / Q000138:chemical synthesis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D008670:Metals / Q000032:analysis*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010847:Picolines / Q000737:chemistry; D011806:Quinolinium Compounds / Q000737:chemistry; D054852:Small Molecule Libraries / Q000737:chemistry*
D000838:Anions; D002412:Cations; D002614:Chelating Agents; D005456:Fluorescent Dyes; D008670:Metals; D009942:Organometallic Compounds; D010847:Picolines; D011806:Quinolinium Compounds; D054852:Small Molecule Libraries