Gniditrin is the main diterpenoid constituent in the bark of Daphne mezereum L.
The bark of Daphne mezereum L. is known as toxic drug due to the presence of diterpene esters. The phytochemical analysis of the bark used for preparation of homeopathic mother tinctures showed that gniditrin was the main diterpene constituent, only in the fruits of D. mezereum mezerein could be detected. The complete NMR data of gniditrin are published for the first time.
Institute of Pharmacy, Freie Universität Berlin, Germany.
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D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis* / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid; D032364:Daphne / Q000737:chemistry*; D004224:Diterpenes / Q000032:analysis* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008419:Materia Medica; D024301:Plant Bark / Q000737:chemistry; D010936:Plant Extracts / Q000032:analysis; D021241:Spectrometry, Mass, Electrospray Ionization
D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; D008419:Materia Medica; D010936:Plant Extracts; C010461:gniditrin