Fe-catalyzed regiodivergent [1,2]-shift of α-aryl aldehydes.
An Fe-catalyzed conversion of aldehydes to ketones via [1,2]-shift has been developed. This skeletal rearrangement shows a wide substrate scope and chemoselectivity profile while exhibiting an excellent [1,2]-aryl or [1,2]-alkyl shift selectivity that is easily switched by electronic effects.
Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona, Spain.
Álvaro
Á
Gutiérrez-Bonet
Areli
A
Flores-Gaspar
Ruben
R
Martin