Identification of malate dehydrogenase 2 as a target protein of the HIF-1 inhibitor LW6 using chemical probes.
College of Pharmacy, Dongguk University-Seoul, 26 Pildong, Junggu, Seoul 100-715 (Korea).
Kyeong
K
Lee
Hyun Seung
HS
Ban
Ravi
R
Naik
Ye Seul
YS
Hong
Seohyun
S
Son
Bo-Kyung
BK
Kim
Yan
Y
Xia
Kyung Bin
KB
Song
Hong-Sub
HS
Lee
Misun
M
Won
D045744:Cell Line, Tumor; D057930:Click Chemistry; D006801:Humans; D051793:Hypoxia-Inducible Factor 1 / Q000037:antagonists & inhibitors*; D008291:Malate Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D019920:Photoaffinity Labels / Q000032:analysis / Q000138:chemical synthesis / Q000378:metabolism*; D011485:Protein Binding
D051793:Hypoxia-Inducible Factor 1; D019920:Photoaffinity Labels; D008291:Malate Dehydrogenase
HIF inhibitors; click chemistry; fluorescent probes; malate dehydrogenase 2; photoaffinity labeling