Increased (18)F-fluoroestradiol uptake in radiation pneumonia.
A 54-year-old metastatic breast cancer patient who had undergone chemotherapy and radiotherapy was transferred to our hospital for further treatment. We utilized (18)F-fluoroestradiol (FES) to assess the estrogen receptor (ER) status of metastatic lesions. Interestingly, high accumulation of (18)F-FES in pneumonia caused by radiation was detected. Hence, this draws oncologists' attention to the possible false-positive result of (18)F-FES, which may lead to inappropriate endocrine therapy.
Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270, Dong'an Road, Xuhui District, Shanghai, China.
Zhongyi
Z
Yang
Yifei
Y
Sun
Zhifeng
Z
Yao
Jing
J
Xue
Yongping
Y
Zhang
Yingjian
Y
Zhang
D001692:Biological Transport; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy; D004958:Estradiol / Q000378:metabolism*; D005189:False Positive Reactions; D005260:Female; D005462:Fluorine Radioisotopes; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis; D049268:Positron-Emission Tomography; D017564:Radiation Pneumonitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism*
D005462:Fluorine Radioisotopes; D004958:Estradiol