Hypervalent iodine/TEMPO-mediated oxidation in flow systems: a fast and efficient protocol for alcohol oxidation.
Hypervalent iodine(III)/TEMPO-mediated oxidation of various aliphatic, aromatic and allylic alcohols to their corresponding carbonyl compounds was successfully achieved by using microreactor technology. This method can be used as an alternative for the oxidation of various alcohols achieving excellent yields and selectivities in significantly shortened reaction times.
Cardiff University, School of Chemistry, Park Place, Cardiff CF10 3AT, UK.
Nida
N
Ambreen
Ravi
R
Kumar
Thomas
T
Wirth
alcohols; carbonyl compounds; flow chemistry; microreactor; oxidation