The use of magnetic resonance spectroscopy in the evaluation of epilepsy.
Magnetic resonance spectroscopy (MRS) is indicated in the imaging protocol of the patient with epilepsy to screen for metabolic derangements such as inborn errors of metabolism and to characterize masses that may be equivocal on conventional magnetic resonance imaging for dysplasia versus neoplasia. Single-voxel MRS with echo time of 35 milliseconds may be used for this purpose as a quick screening tool in the epilepsy imaging protocol. MRS is useful in the evaluation of both focal and generalized epilepsy.
Division of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA. pcaruso@partners.org
Paul A
PA
Caruso
Jason
J
Johnson
Ron
R
Thibert
Otto
O
Rapalino
Sandra
S
Rincon
Eva-Maria
EM
Ratai
D015415:Biomarkers / Q000378:metabolism*; D001704:Biopolymers / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D004827:Epilepsy / Q000175:diagnosis* / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
D015415:Biomarkers; D001704:Biopolymers
(1)H MR spectroscopy; Epilepsy; Focal cortical dysplasia; Inborn error of metabolism