Inter-individual and inter-strain variations in zebrafish locomotor ontogeny.
Zebrafish exhibit remarkable alterations in behaviour and morphology as they develop from early larval stages to mature adults. In this study we compare the locomotion parameters of six common zebrafish strains from two different laboratories to determine the stability and repeatability of these behaviours. Our results demonstrate large variability in locomotion and fast swim events between strains and between laboratories across time. These data highlight the necessity for careful, strain-specific controls when analysing locomotor phenotypes and open up the possibility of standardising the quantification of zebrafish behaviour at multiple life stages.
Zebrafish Neurogenetics, Neurobiologie et Développement, Insitut de Neurobiologie Albert Fessard, Centre National de la Recherche Scientifique, Gif-sur-Yvette, Essonne, France.
Merlin
M
Lange
Frederic
F
Neuzeret
Benoit
B
Fabreges
Cynthia
C
Froc
Sebastien
S
Bedu
Laure
L
Bally-Cuif
William H J
WH
Norton
D000704:Analysis of Variance; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D005260:Female; D014644:Genetic Variation / Q000502:physiology*; D007814:Larva / Q000502:physiology*; D008124:Locomotion / Q000502:physiology*; D008297:Male; D013550:Swimming / Q000502:physiology; D015027:Zebrafish / Q000502:physiology*