[Thrombocytopenia during pregnancy].
Thrombocytopenia during pregnancy can be caused by a broad variety of disorders. An early diagnosis is essential for timely and adequate therapy. In cases of severe thrombocytopenia, a multidisciplinary approach by a team of obstetricians, haematologists and anaesthesiologists is needed. We describe a 30-year-old patient at a gestational age of 35 weeks who presented with preterm rupture of membranes. Coincidentally, she also had severe thrombocytopenia that proved to be due to immune thrombocytopenia (ITP). The severe thrombocytopenia persisted despite standard first-line treatment with corticosteroids and intravenous immunoglobulins. Based on this case report we discuss the differential diagnosis of thrombocytopenia during pregnancy with a focus on the management of ITP in pregnant women.
Erasmus Medisch Centrum, Rotterdam.
C
C
Rokx
R M
RM
Swart
A A
AA
van Houten
M B
MB
Leys
J J
JJ
Duvekot
P A W
PA
Te Boekhorst
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007136:Immunoglobulins / Q000627:therapeutic use; D007752:Obstetric Labor, Premature / Q000209:etiology; D010976:Platelet Count; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D011256:Pregnancy Outcome; D011295:Prenatal Care; D013921:Thrombocytopenia / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy
D000305:Adrenal Cortex Hormones; D007136:Immunoglobulins