The use of111Ag as a tool for studying biological distribution of silver-based antimicrobials.
Recently, there has been an emergence of significant interest in silver-based antimicrobials. Our goal was to develop a radioactive tracer for investigating the biological fate of such compounds. Purified111Ag was incorporated into the methylated caffeine analogue, IC1 to yield the silver carbene complex designated as [111Ag]SCC1 and investigated in biodistribution studies.
Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, 510 S. Kingshighway Blvd, St. Louis, MO 63110. ; Tel: 314-362-0284; Tel: 314-367-5537; Tel: 314-362-8154.
Tolulope A
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Aweda
Oluwatayo
O
Ikotun
Tara
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Mastren
Carolyn L
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Cannon
Brian
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Wright
Wiley J
WJ
Youngs
Cathy
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Cutler
James
J
Guthrie
Suzanne E
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Lapi