Polyarteritis nodosa in childhood: recognition of early dermatologic signs may prevent morbidity.
Systemic polyarteritis nodosa (PAN) is a vasculitis that affects small to medium-size arteries. Onset in childhood is rare and can cause significant morbidity. Often, cutaneous manifestations can provide early clues toward diagnosis. This article describes a case of childhood systemic PAN that presented with fever, a necrotic skin lesion, and oral ulceration. Intestinal perforation complicated this case. Prompt recognition of childhood PAN is important to prevent serious complications.
Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama.
Kathleen M
KM
Beckum
David J
DJ
Kim
David R
DR
Kelly
Peter
P
Weiser
Diego A
DA
Lara
Amy
A
Theos
D002675:Child, Preschool; D003106:Colon / Q000473:pathology; D042241:Early Diagnosis; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D009017:Morbidity; D010488:Polyarteritis Nodosa / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D012867:Skin / Q000473:pathology
D007166:Immunosuppressive Agents