Palladium-catalyzed selective fluorination of o-carboranes.
A Pd(II)-catalyzed direct selective fluorination reaction of carboranes using a F(+) reagent has been developed, leading to a series of polyfluorocarboranes in high isolated yields. The mechanism involving electrophilic B-H activation, oxidation of Pd(II) by F(+) species, and reductive elimination is proposed.
Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
Zaozao
Z
Qiu
Yangjian
Y
Quan
Zuowei
Z
Xie
D001880:Boranes / Q000737:chemistry*; D002384:Catalysis; D054879:Halogenation; D010165:Palladium / Q000737:chemistry*; D013379:Substrate Specificity
D001880:Boranes; D010165:Palladium