Teeth and tongue discoloration after linezolid treatment in children.
We describe 3 children who developed teeth and tongue discoloration while receiving intravenous linezolid for 2 to 3 weeks. Linezolid was coadministered with piperacillin-tazobactam or meropenem. Teeth and tongue discoloration was reversible with dental cleaning after discontinuation of linezolid. We review the published pediatric and adult cases regarding teeth and tongue discoloration after linezolid administration.
From the First Department of Pediatrics, University of Athens, "Aghia Sophia" Children's Hospital, Athens, Greece.
Theoni
T
Petropoulou
Evagelia
E
Lagona
Vassiliki
V
Syriopoulou
Athanasios
A
Michos
D000081:Acetamides / Q000009:adverse effects* / Q000627:therapeutic use; D000293:Adolescent; D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006760:Hospitalization; D006801:Humans; D000069349:Linezolid; D008297:Male; D023303:Oxazolidinones / Q000009:adverse effects* / Q000627:therapeutic use; D014059:Tongue / Q000187:drug effects* / Q000473:pathology; D014075:Tooth Discoloration / Q000139:chemically induced* / Q000473:pathology
D000081:Acetamides; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid