Guidelines for the management of accidental tetanus in adult patients.
Although tetanus can be prevented by appropriate immunization, accidental tetanus continues to occur frequently in underdeveloped and developing countries. Tetanus mortality rates remain high in these areas, and studies regarding the best therapy for tetanus are scarce. Because of the paucity of data on accidental tetanus and the clinical relevance of this condition, the Associação de Medicina Intensiva Brasileira (AMIB) organized a group of experts to develop these guidelines, which are based on the best available evidence for the management of tetanus in patients requiring admission to the intensive care unit. The guidelines discuss the management of tetanus patients in the intensive care unit, including the use of immunoglobulin therapy, antibiotic therapy, management of analgesics, sedation and neuromuscular blockade, management of dysautonomia and specific issues related to mechanical ventilation and physiotherapy in this population.
Thiago
T
Lisboa
Yeh-Li
YL
Ho
Gustavo Trindade
GT
Henriques Filho
Janete Salles
JS
Brauner
Jorge Luis Dos Santos
JL
Valiatti
Juan Carlos
JC
Verdeal
Flavia Ribeiro
FR
Machado