Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores.
Novel organic photoCORMs based on micelle-encapsulated unsaturated cyclic α-diketones were designed and synthesized. These photoCORMs can be activated by visible light, have potentially low toxicity, allow the delivery of carbon monoxide to be monitored by fluorescence imaging techniques, and thus are useful tools for the study of the biological function of CO.
Department of Chemistry, University of Central Florida, Orlando, FL 32816, USA.
Ping
P
Peng
Chaoming
C
Wang
Zheng
Z
Shi
Valentine K
VK
Johns
Liyuan
L
Ma
Jeremiah
J
Oyer
Alicja
A
Copik
Robert
R
Igarashi
Yi
Y
Liao
D002214:Capsules; D002248:Carbon Monoxide / Q000032:analysis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry; D008027:Light; D008823:Micelles
D002214:Capsules; D005456:Fluorescent Dyes; D007659:Ketones; D008823:Micelles; D002248:Carbon Monoxide