A 78-year-old man with rapidly-progressing sarcomatoid renal cell carcinoma.
We report a case of metastatic sarcomatoid renal cell carcinoma (SRCC), which presented as nephrotic syndrome with diffuse peripheral edema. At the time of diagnosis, the metastatic disease involved bone, with peritoneal lymphadenopathy. The nephrotic syndrome did not improve after nephrectomy. Systemic disease progressed quickly postoperatively. The sarcomatoid renal cell carcinoma in this case had an aggressive clinical course. CNS metastasis quickly developed, and the patient passed away soon after.
University of New England, College of Osteopathic Medicine, USA.
Jennie Myers-Pacheco
JM
Wang
Xuemei
X
Li
D000368:Aged; D001859:Bone Neoplasms / Q000175:diagnosis / Q000556:secondary*; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D010535:Laparoscopy; D008207:Lymphatic Metastasis; D008297:Male; D009392:Nephrectomy; D009404:Nephrotic Syndrome / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D010537:Peritoneum; D014057:Tomography, X-Ray Computed