Age differences in the neuroelectric adaptation to meaningful sounds.
Much of what we know regarding the effect of stimulus repetition on neuroelectric adaptation comes from studies using artificially produced pure tones or harmonic complex sounds. Little is known about the neural processes associated with the representation of everyday sounds and how these may be affected by aging. In this study, we used real life, meaningful sounds presented at various azimuth positions and found that auditory evoked responses peaking at about 100 and 180 ms after sound onset decreased in amplitude with stimulus repetition. This neural adaptation was greater in young than in older adults and was more pronounced when the same sound was repeated at the same location. Moreover, the P2 waves showed differential patterns of domain-specific adaptation when location and identity was repeated among young adults. Background noise decreased ERP amplitudes and modulated the magnitude of repetition effects on both the N1 and P2 amplitude, and the effects were comparable in young and older adults. These findings reveal an age-related difference in the neural processes associated with adaptation to meaningful sounds, which may relate to older adults' difficulty in ignoring task-irrelevant stimuli.
Department of Occupational Therapy and Centre for Neuroscience, University of Alberta, Edmonton, Canada.
Ada W S
AW
Leung
Yu
Y
He
Cheryl L
CL
Grady
Claude
C
Alain
D000161:Acoustic Stimulation; D000222:Adaptation, Physiological; D000328:Adult; D000367:Age Factors; D000368:Aged; D001288:Attention; D001303:Auditory Cortex / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology*; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009622:Noise; D011930:Reaction Time / Q000502:physiology; D013016:Sound