The role of surgery in patients with clinical n2 disease.
Patients with N2 non-small cell lung carcinoma have ipsilateral mediastinal adenopathy with stage IIIA disease. Most of these patients are still staged solely using imaging techniques, which causes a significant error in staging if not combined with some form of surgical staging of the mediastinum. N2 disease forms a spectrum of disease ranging from occult microscopic disease to bulky multistation adenopathy. Proper understanding of the prognosis and treatment implications for each form of mediastinal lymph node metastases has led to the selective use of surgery to treat these patients. This article reviews the role of surgery in the management of patients with N2 mediastinal involvement.
Department of Thoracic and Cardiovascular Surgery, MD Anderson Cancer Center, 1400 Pressler, FCT 19.5066, Unit 1489, Houston, TX 77030-4009, USA. rjmehran@mdanderson.org
Reza
R
Mehran
D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis / Q000601:surgery* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000601:surgery* / Q000628:therapy; D008198:Lymph Nodes / Q000473:pathology / Q000601:surgery; D008207:Lymphatic Metastasis; D008482:Mediastinum / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D011013:Pneumonectomy; D011379:Prognosis; D016896:Treatment Outcome
Chemotherapy; Metastatic mediastinal lymph node; Non–small lung carcinoma; Radiation therapy; Surgery