[Progress in myofibroblast and its application in forensic medicine].
The myofibroblasts have dual characteristics of smooth muscle cells and fibroblasts. In repairing tissular wound, myofibroblasts are involved in fibrogenesis and remodeling the extracellular matrix of the fibrotic cascades reaction. The review describes the morphological characteristics and biological behaviors of myofibroblasts and the application of skin wound age determination, which may provide reference for research in forensic medicine.
Key Laboratory of Evidence Science, Ministry of Education, China University of Political Science and Law, Beijing 100040, China. yutianshui-2000@sohu.com
Tian-Shui
TS
Yu
Yue
Y
Ling
Da-Wei
DW
Guan
D000199:Actins / Q000378:metabolism; D000818:Animals; D002454:Cell Differentiation; D002478:Cells, Cultured; D005109:Extracellular Matrix / Q000378:metabolism; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism / Q000502:physiology; D049429:Forensic Pathology / Q000379:methods*; D006801:Humans; D009130:Muscle, Smooth / Q000166:cytology / Q000502:physiology; D058628:Myofibroblasts / Q000166:cytology / Q000378:metabolism / Q000502:physiology; D012867:Skin / Q000293:injuries; D013997:Time Factors; D014945:Wound Healing; D014947:Wounds and Injuries / Q000378:metabolism / Q000473:pathology
D000199:Actins