Pulse granuloma involving Meckel's diverticulum: a case report and literature review.
Pulse granuloma is a rare, benign entity that most likely represents a reaction to vegetable material and is characterized by hyaline rings and foreign-body giant cells. We report a case of a pulse granuloma involving Meckel's diverticulum. The patient presented with abdominal pain and radiological findings consistent with Meckel's diverticulum. Microscopic examination of the resected tissue confirmed diagnosis of Meckel's diverticulum with small bowel mucosa. Peridiverticular foreign-body giant cells, hyaline rings and circular structures containing calcified basophilic granules were also identified, consistent with pulse granuloma. Pulse granulomas have been reported in a variety of locations, most commonly in the oral cavity. To the best of our knowledge, this is the first reported example of pulse granuloma in Meckel's diverticulum. Familiarity with pulse granuloma allows for the timely and accurate diagnosis of this entity, particularly in sites not previously described in the literature.
Thomas Jefferson University Hospital, Methodist Division, Philadelphia, PA 19148, USA. julie.karp@jefferson.edu
J K
JK
Karp
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A
Davis
P J
PJ
Read
A
A
Mashayekh
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A
Bombonati
F
F
Palazzo
D001491:Basophils; D003937:Diagnosis, Differential; D015743:Giant Cells, Foreign-Body / Q000473:pathology; D006099:Granuloma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D006818:Hyalin; D008297:Male; D008467:Meckel Diverticulum / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D011877:Radionuclide Imaging