Pathogen profile in men with inflammation of paraurethral glands.
OBJECTIVE
To investigate the pathogen profile in men with inflammation of the paraurethral glands.


METHODS
We enrolled 40 patients with first-onset, drug-naive inflammation of the paraurethral glands. Discharge from the lesions was collected for Gram staining. Microscopy was performed for screening for trichomonads and detecting Gram-negative intracellular diplococci within phagocytes. Cultures for detection of Neisseria gonorrhoeae, Ureaplasma urealyticum and other bacteria, and Chlamydia-trachomatis-associated antigens were performed. PCR was conducted for herpes simplex virus type 1 or 2.


RESULTS
From these 40 patients, there were nine microbial species, which included Gram-negative bacteria (23 cases, 54.8%), Gram-positive bacteria (15 cases, 35.7%) and other pathogens (4 cases, 9.5%). The top three pathogens were gonococci (38.1%), Staphylococcus aureus (16.7%) and Escherichia coli (14.3%).


CONCLUSIONS
Inflammation of paraurethral glands in men may be caused by a variety of pathogens and not just by gonococcal infection.
Department of Dermatology, First People's Hospital of Changshu City, Changshu Hospital, Affiliated to Soochow University, , Changshu, Jiangsu Province, P R China.
Wenge
W
Fan
Qingsong
Q
Zhang
Tingwang
T
Jiang
D000328:Adult; D001424:Bacterial Infections / Q000150:complications* / Q000175:diagnosis; D002846:Chromatography, Affinity; D006561:Herpes Simplex / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014521:Urethra / Q000382:microbiology / Q000473:pathology*
Infection; Inflammation; Males