isomiRID: a framework to identify microRNA isoforms.
CONCLUSIONS
MicroRNAs (miRNAs) have been extensively studied owing to their important regulatory roles in genic expression. An increasingly number of reports are performing extensive data mining in small RNA sequencing libraries to detect miRNAs isoforms and also 5' and 3' post-transcriptional nucleotide additions, as well as edited miRNAs sequences. A ready to use pipeline, isomiRID, was developed to standardize and automatize the search for miRNAs isoforms in high-throughput small RNA sequencing libraries.


BACKGROUND
isomiRID is a command line Python script available at http://www.ufrgs.br/RNAi/isomiRID/.
Genetics and Molecular Biology Graduation Program and Department of Biophysics, Center of Biotechnology, Universidade Federal do Rio Grande do Sul - UFRGS, Avenida Bento Goncalves 9500, Predio 43431, Sala 213, Porto Alegre, Brasil, CEP 91501-970.
Luiz Felipe Valter
LF
de Oliveira
Ana Paula
AP
Christoff
Rogerio
R
Margis
D001483:Base Sequence; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D006801:Humans; D020407:Internet; D035683:MicroRNAs / Q000032:analysis* / Q000235:genetics; D020033:Protein Isoforms / Q000032:analysis / Q000235:genetics; D017423:Sequence Analysis, RNA / Q000379:methods*; D012984:Software
D035683:MicroRNAs; D020033:Protein Isoforms