Thrombocytopenia induces multiple intracranial hemorrhages in patients with severe burns: A review of 16 cases.
The aim of this study was to explore the etiology and diagnosis of multiple intracranial hemorrhages (ICHs) following severe burns, with a retrospective review of 16 cases of severe burns further complicated by multiple ICHs. Using cranial CT scans of the brains, we identified that all patients presented with low platelet counts and coagulation abnormalities prior to intracranial hemorrhaging. Following conventional treatment and various supporting treatments, five cases succumbed following a progressive reduction in blood platelet levels and the ICHs were cured in 11 cases following the restoration of normal platelet levels. We conclude that low platelet counts and coagulation abnormalities may cause multiple ICHs following severe burns and early diagnosis and treatment is the key to successful treatment.
The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Jianda
J
Zhou
Jinyan
J
Liu
Chengqun
C
Luo
Feng
F
Hu
Rui
R
Liu
Zizi
Z
Chen
Yao
Y
Chen
Wu
W
Xiong
Jianfei
J
Xie
Quanyong
Q
He
Chaoqi
C
Yin
Shaohua
S
Wang
Yanwen
Y
Zhang
Sainan
S
Zeng
burn; coagulation abnormalities; complication; multiple intracranial hemorrhages; platelet