[Blood transfusion and infectious diseases].
Blood transfusion is essential in current medical treatment. In the era of selling blood, around 50% of recipients seemed to be infected by hepatitis virus. After the establishment of the blood donation system and many safety measures, the risk of blood contamination has decreased markedly; however, blood products still have a risk of known and unknown pathogens. In this manuscript, we discuss the remaining problems of HBV and HIV-1. As emerging infectious diseases, we examine Trypanosoma crusi, West Nile virus, Chikungunya virus, and Dengue virus. Finally, XMRV is exemplified as a rumored virus. Gathering accurate information about pathogens and preparing for outbreaks in advance are crucial for blood safety.
Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Musashimurayama 208-0011, Japan. 130hama@nih.go.jp
Isao
I
Hamaguchi
D001782:Blood Donors; D058731:Blood Safety; D017848:Blood-Borne Pathogens / Q000302:isolation & purification; D021821:Communicable Diseases, Emerging / Q000097:blood*; D006801:Humans; D012306:Risk; D065227:Transfusion Reaction