Metastatic renal cell carcinoma in the nasopharynx.
Metastatic renal cell carcinoma of the nasopharynx, nasal cavity, and paranasal sinuses can be misdiagnosed as primary malignant or benign diseases. A 33-year-old male attended our outpatient clinic complaining of difficulty breathing through the nose, bloody nasal discharge, postnasal drop, snoring, and discharge of phlegm. Endoscopic nasopharyngeal examination showed a vascularized nasopharyngeal mass. Under general anesthesia, multiple punch biopsies were taken from the nasopharynx. Pathologically, the tumor cells had clear cytoplasm and were arranged in a trabecular pattern lined by a layer of endothelial cells. After the initial pathological examination, the pathologist requested more information about the patient's clinical status. A careful history revealed that the patient had undergone left a nephrectomy for a kidney mass diagnosed as renal cell carcinoma 3 years earlier. Subsequently, nasopharyngeal metastatic renal cell carcinoma was diagnosed by immunohistochemical staining with CD10 and vimentin. Radiotherapy was recommended for treatment.
Department of Otorhinolaryngology, Yenikent Government Hospital, Sakarya, Turkey.
Yavuz
Y
Atar
Ilhan
I
Topaloglu
Deniz
D
Ozcan
D000328:Adult; D001706:Biopsy; D002292:Carcinoma, Renal Cell / Q000473:pathology* / Q000532:radiotherapy; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000556:secondary*; D009305:Nasopharynx / Q000473:pathology; D009333:Neck / Q000000981:diagnostic imaging; D009362:Neoplasm Metastasis; D015260:Neprilysin / Q000032:analysis; D011859:Radiography; D014746:Vimentin / Q000032:analysis
D014746:Vimentin; D015260:Neprilysin