Intraoperative dexamethasone implant in uveitis patients with cataract undergoing phacoemulsification.
OBJECTIVE
To study the role of intraoperative intravitreal dexamethasone implant in patients of uveitis with cataract undergoing phacoemulsification.


METHODS
This prospective study included 20 patients with uveitis and cataract who underwent phacoemulsification with intraocular lens implantation. Ten patients (10 eyes) received an intravitreal dexamethasone implant intraoperatively (implant group), and 10 patients (10 eyes) received oral steroids (steroid group). Outcome measures were best-corrected visual acuity (BCVA), intraocular pressure (IOP), and central macular thickness (CMT).


RESULTS
The logMar BCVA improved from 0.93 ± 0.49 to 0.23 ± 0.23 and from 1.29 ± 0.47 to 0.22 ± 0.16 in the implant and steroid groups, respectively. Postoperative IOP and CMT showed no statistically significant differences between the two groups. None of the patients in either group had significant IOP rise requiring any surgical intervention.


CONCLUSIONS
A single intraoperative intravitreal dexamethasone implant during phacoemulsification in patients of uveitis with cataract seems to be an effective alternative for postoperative oral steroids.
Advanced Eye Centre, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research , Chandigarh , India.
Adit
A
Gupta
Jagat
J
Ram
Amod
A
Gupta
Vishali
V
Gupta
D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D002386:Cataract / Q000150:complications* / Q000175:diagnosis; D003907:Dexamethasone / Q000008:administration & dosage*; D004343:Drug Implants; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007432:Intraoperative Period; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D011183:Postoperative Complications / Q000517:prevention & control; D011446:Prospective Studies; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014605:Uveitis / Q000150:complications / Q000188:drug therapy* / Q000601:surgery; D055815:Young Adult
D000893:Anti-Inflammatory Agents; D004343:Drug Implants; D003907:Dexamethasone