The merged basins of signal transduction pathways in spatiotemporal cell biology.
Numerous evidences have indicated that a signal system is composed by signal pathways, each pathway is composed by sub-pathways, and the sub-pathway is composed by the original signal terminals initiated with a protein/gene. We infer the terminal signals merged signal transduction system as "signal basin". In this article, we discussed the composition and regulation of signal basins, and the relationship between the signal basin control and triple W of spatiotemporal cell biology. Finally, we evaluated the importance of the systemic regulation to gene expression by signal basins under triple W. We hope our discussion will be the beginning to cause the attention for this area from the scientists of life science.
Department of Cell Biology, School of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi, China.
Yingchun
Y
Hou
Yang
Y
Hou
Siyu
S
He
Caixia
C
Ma
Mengyao
M
Sun
Huimin
H
He
Ning
N
Gao
D000818:Animals; D003585:Cell Biology; D005786:Gene Expression Regulation; D053263:Gene Regulatory Networks; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics / Q000378:metabolism*; D008954:Models, Biological; D015398:Signal Transduction / Q000235:genetics; D049490:Systems Biology
D047908:Intracellular Signaling Peptides and Proteins