Intraoral herpes simplex virus infection in a patient with common variable immunodeficiency.
We report a challenging case of an atypical presentation of recrudescent herpes simplex virus infection in a patient with common variable immunodeficiency. Oral infections in immunosuppressed patients may present with unusual clinical features that can mimic non-infectious diseases. This report discusses the diagnostic steps necessary for definitive diagnosis and to guide appropriate and effective management.
Oral medicine resident; Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA, USA; Assistant Professor, Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA. Electronic address: avilla@post.harvard.edu.
Alessandro
A
Villa
Nathaniel S
NS
Treister
D000212:Acyclovir / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use*; D017074:Common Variable Immunodeficiency / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D017676:Lichen Planus, Oral / Q000175:diagnosis*; D008875:Middle Aged; D009894:Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy*; D013283:Stomatitis, Herpetic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D000077483:Valacyclovir; D014633:Valine / Q000031:analogs & derivatives* / Q000627:therapeutic use
D000998:Antiviral Agents; D014633:Valine; D000077483:Valacyclovir; D000212:Acyclovir