Cystovirus maturation at atomic resolution.
Cystoviruses are dsRNA viruses that infect bacteria and include bacteriophages Φ8 and Φ6. In this issue of Structure, El Omari and colleagues and Nemecek and colleagues report crystal structures of capsid protein P1 pentamers found in procapsid cores of Φ8 and Φ6. The two structures show a striking resemblance in the absence of sequence similarity and offer new mechanistic and evolutionary insights.
Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
David
D
Veesler
John E
JE
Johnson
D036022:Capsid Proteins / Q000737:chemistry*; D017910:Cystoviridae / Q000648:ultrastructure*; D017105:Pseudomonas Phages / Q000648:ultrastructure*; D012087:Reoviridae
D036022:Capsid Proteins