Modeling and analysis of propulsion in the multiflagellated micoorganism Giardia lamblia.
The goal of this work was to analyze the propulsion of multiflagellated microorganisms, and to draw insight to the underlying physics and biology of the movement. Giardia lamblia was chosen as the model organism due to its unique ability to mechanically attach to various surfaces, its rapid movement, and its fine control over steering and navigation. In this work, a mechanics model was utilized to study the mechanics and propulsive contribution of the ventral and anterior flagella in Giardia. It was discovered that energy is supplied mainly at the proximal portion of these flagella, supporting the hypothesis that a decreasing adenosine triphosphate (ATP) gradient along the length of the flagella would not affect the motion observed. Similarly, the elasticity of the flagella allows the energy input at the proximal portion to be transferred to the distal portion, where the majority of thrust is generated. Specifically, we found that the ventral flagella are the driving force for planar propulsion and turning, while the anterior flagella are used for steering and control.
Department of Mechanical, Aerospace, and Biomedical Engineering, University of Tennessee, Knoxville, Tennessee 37996, USA.
Scott C
SC
Lenaghan
Jun
J
Chen
Mingjun
M
Zhang
D001696:Biomechanical Phenomena; D032701:Biomimetics; D005407:Flagella / Q000378:metabolism*; D016829:Giardia lamblia / Q000166:cytology* / Q000502:physiology*; D008954:Models, Biological; D020409:Molecular Motor Proteins / Q000378:metabolism; D009068:Movement
D020409:Molecular Motor Proteins