Interpersonal problems as predictors of alliance, symptomatic improvement and premature termination in treatment of depression.
BACKGROUND
Previous studies reported inconsistent findings regarding the association of interpersonal problems with therapy outcome. The current study investigates if interpersonal problems predict process and outcome of three different treatments for depression.


METHODS
The data originate from a randomized clinical trial comparing supportive-expressive psychotherapy, antidepressant medication and pill-placebo for treatment of depression. Interpersonal problems were used as predictors of alliance, symptomatic improvement and premature termination of treatment.


RESULTS
Interpersonal problems related to communion predicted better alliances, but slower symptomatic improvement. Low agency predicted slower symptomatic improvement in supportive-expressive psychotherapy, but not in the medication or placebo condition. Lower interpersonal distress was associated with an increased likelihood to terminate treatment prematurely.


CONCLUSIONS
The sample size did not allow the detection of small effects within the treatment groups.


CONCLUSIONS
Interpersonal problems are influential for the treatment of depression, but parts of their effects depend on the type of treatment.
Clinic for General Internal Medicine and Psychosomatics, University of Heidelberg, Thibautstr. 2, 69115 Heidelberg, Germany; Derner Institute of Advanced Psychological Studies, Adelphi University, USA. Electronic address: ulrike.dinger@med.uni-heidelberg.de.
Ulrike
U
Dinger
Derner Institute of Advanced Psychological Studies, Adelphi University, USA.
Sigal
S
Zilcha-Mano
Chestnut Hill College, USA.
Kevin S
KS
McCarthy
Department of Psychiatry, University of Pennsylvania, USA.
Marna S
MS
Barrett
Derner Institute of Advanced Psychological Studies, Adelphi University, USA.
Jacques P
JP
Barber
D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use; D003299:Cooperative Behavior; D003863:Depression; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000523:psychology* / Q000628:therapy*; D005260:Female; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D008875:Middle Aged; D010043:Outcome and Process Assessment, Health Care; D010349:Patient Compliance
D000928:Antidepressive Agents
Depression; Interpersonal problems; Psychotherapy