Albumin as a drug delivery and diagnostic tool and its market approved products.
Albumin is one of the most extensively studied endogenous proteins which are used in the fabrication of drug delivery and diagnostic technologies during last 10 years. This review provides a summary of products involving the use of albumin as a drug delivery tool for getting better the pharmacokinetics of a drug by developing the targetted drug delivery systems and diagnosing the pathologies. Using albumin, following market approved products have been developed: Levemir and Victoza (antidiabetic product), Abraxane (antimetastatic breast cancer product), and Nanocoll and Albures (for lymphoscintigraphy and diagnosis of cancer and rheumatoid arthritis).
Department of Pharmacy, Government College University, Faisalabad, Pakistan.
Ayesha
A
Sethi
Muhammad
M
Sher
Muhammad Rouf
MR
Akram
Sabiha
S
Karim
Sonia
S
Khiljee
Ashif
A
Sajjad
Syed Nisar Hussain
SN
Shah
Ghulam
G
Murtaza
D000068196:Albumin-Bound Paclitaxel; D000418:Albumins / Q000008:administration & dosage* / Q000737:chemistry; D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D004337:Drug Carriers; D052216:Glucagon-Like Peptide 1 / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000737:chemistry; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000737:chemistry; D000069057:Insulin Detemir; D049528:Insulin, Long-Acting / Q000008:administration & dosage / Q000737:chemistry; D000069450:Liraglutide; D017239:Paclitaxel / Q000008:administration & dosage / Q000737:chemistry; D011237:Predictive Value of Tests; D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin
D000068196:Albumin-Bound Paclitaxel; D000418:Albumins; D000970:Antineoplastic Agents; D004337:Drug Carriers; D007004:Hypoglycemic Agents; D049528:Insulin, Long-Acting; D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; C083602:technetium Tc 99m nanocolloid; D000069057:Insulin Detemir; D000069450:Liraglutide; D052216:Glucagon-Like Peptide 1; D017239:Paclitaxel