The impact of previous traumatic brain injury on health and functioning: a TRACK-TBI study.
The idea that multiple traumatic brain injury (TBI) can have a cumulative detrimental effect on functioning is widely accepted. Most research supporting this idea comes from athlete samples, and it is not known whether remote history of previous TBI affects functioning after subsequent TBI in community-based samples. This study investigates whether a previous history of TBI with loss of consciousness (LOC) is associated with worse health and functioning in a sample of individuals who require emergency department care for current TBI. Twenty-three percent of the 586 individuals with current TBI in the Transforming Research and Clinical Knowledge in Traumatic Brain Injury study reported having sustained a previous TBI with LOC. Individuals with previous TBI were more likely to be unemployed (χ(2)=17.86; p=0.000), report a variety of chronic medical and psychiatric conditions (4.75≤χ(2)≥24.16; p<0.05), and report substance use (16.35≤χ(2)≥27.57; p<0.01) before the acute injury, compared to those with no previous TBI history. Those with a previous TBI had less-severe acute injuries, but experienced worse outcomes at 6-month follow-up. Results of a series of regression analyses controlling for demographics and acute injury severity indicated that individuals with previous TBI reported more mood symptoms, more postconcussive symptoms, lower life satisfaction, and had slower processing speed and poorer verbal learning, compared to those with no previous TBI history. These findings suggest that history of TBI with LOC may have important implications for health and psychological functioning after TBI in community-based samples.
1 Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai , New York, New York.
Kristen
K
Dams-O'Connor
Lisa
L
Spielman
Ayushi
A
Singh
Wayne A
WA
Gordon
Hester F
HF
Lingsma
Andrew I R
AI
Maas
Geoffrey T
GT
Manley
Pratik
P
Mukherjee
David O
DO
Okonkwo
Ava M
AM
Puccio
David M
DM
Schnyer
Alex B
AB
Valadka
John K
JK
Yue
Esther L
EL
Yuh
D000328:Adult; D001930:Brain Injuries / Q000175:diagnosis* / Q000453:epidemiology* / Q000503:physiopathology; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020127:Recovery of Function / Q000502:physiology; D057566:Self Report; D055815:Young Adult