Intraperitoneal bupivacaine for pain relief after minilaparoscopy in patients with infertility.
OBJECTIVE
To evaluate the efficacy of intraperitoneal bupivacaine to reduce post operative pain after diagnostic minilaparoscopy in patients with infertility.


METHODS
A prospective randomized study was performed.


METHODS
The study group consisted of 104 women with infertility undergoing diagnostic minilaparoscopy. At the end of the procedure, the treatment group (Group A) was given 10 mL of intraperitoneal 0.25 % bupivacaine (100 mg) and the control group (Group B) given 10 mL of intraperitoneal saline. Post operative pain was recorded with the use of a visual analog scale with scores ranging from 1 to 10 at 2, 4, 6 and 8 h intervals after the surgery. Additional analgesics given to the patients in the post operative period and any other side effects were noted.


RESULTS
The treatment group had significantly lower pain scores at 2, 4, 6 and 8 h after the procedure (P < 0.05). The need for post operative analgesics also was significantly lower in the treatment group (P = 0.007).


CONCLUSIONS
Post operative intraperitoneal bupivacaine administration is beneficial for patients undergoing diagnostic minilaparoscopy. It can significantly decrease post operative pain for up to 8 h and reduce the need for additional analgesics.
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Room No 3076, Third Floor, Teaching Block, Ansarinagar, New Delhi, 110029, India.
Kallol Kumar
KK
Roy
Murali
M
Subbaiah
Moumita
M
Naha
Sunesh
S
Kumar
Jai Bhagwan
JB
Sharma
Nandini
N
Jahagirdar
D000328:Adult; D000700:Analgesics / Q000008:administration & dosage; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000175:diagnosis*; D007274:Injections, Intraperitoneal; D010535:Laparoscopy / Q000295:instrumentation / Q000379:methods*; D059408:Pain Management; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D011446:Prospective Studies
D000700:Analgesics; D000779:Anesthetics, Local; D002045:Bupivacaine