Understanding the role of cleaning in the control of Salmonella Typhimurium in grower-finisher pigs: a modelling approach.
Salmonella Typhimurium (STM) infection in pigs represents a considerable food safety concern. This study used mathematical modelling to evaluate the effectiveness of cleaning (faeces removal) as a measure to control STM spread among grower-finisher pigs. A modified Susceptible-Infected-Recovered-Susceptible (SIRS) model of STM transmission through a contaminated environment was developed. Infected pigs were divided into three states according to the pathogen level being shed in their faeces. Infection transmission was evaluated using the basic reproduction number (R 0) and the prevalence of infectious pigs at slaughter age. Although increased frequency and efficiency of cleaning did reduce the prevalence of STM shedding at the time of slaughter, these efforts alone were not capable of eliminating the infection from the population. The level of STM faecal shedding by infectious pigs strongly influenced the infection spread and prevalence at slaughter. To control STM in pigs, cleaning should be combined with vaccination and/or isolation of high-level shedders.
Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
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Gautam
Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
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Lahodny
Department of Mathematics and Statistics, University of Missouri-Kansas City, Kansas City, MO, USA.
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Bani-Yaghoub
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
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Morley
Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
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Ivanek
D000818:Animals; D005243:Feces / Q000382:microbiology; D017053:Infection Control; D008954:Models, Biological; D015203:Reproducibility of Results; D012481:Salmonella Infections, Animal / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D012486:Salmonella typhimurium; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission