Lung perfusion and ventilation during implantation of left ventricular assist device as a strategy to avoid postoperative pulmonary complications and right ventricular failure.
Right ventricular failure is a major contributor to increased morbidity and mortality in patients undergoing left ventricular assist device implantation. Cardiopulmonary bypass is associated with increased pulmonary ischaemia and pulmonary vascular resistance. Continuous pulmonary perfusion and ventilation represents an emerging strategy for pulmonary protection during cardiac surgery. We hypothesize that this technique may have a pivotal role in reducing postoperative right ventricular dysfunction in high-risk patients undergoing LVAD placement.
Division of Cardiothoracic Surgery, Heart/Lung Transplantation and Artificial Heart Programs, University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, FL, USA.
Francisco Igor B
FI
Macedo
Anthony L
AL
Panos
Fotios M
FM
Andreopoulos
Tomas A
TA
Salerno
Si M
SM
Pham
D000369:Aged, 80 and over; D002315:Cardiopulmonary Bypass; D006333:Heart Failure / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006353:Heart-Assist Devices; D006439:Hemodynamics; D006801:Humans; D008171:Lung Diseases / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D010477:Perfusion / Q000379:methods*; D019919:Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation*; D011652:Pulmonary Circulation; D012121:Respiration, Artificial; D016896:Treatment Outcome; D018497:Ventricular Dysfunction, Right / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D016277:Ventricular Function, Left; D016278:Ventricular Function, Right
Left ventricular assist device; Lung perfusion/ventilation; Pulmonary protection; Right ventricular failure