Transcostal high-intensity focused ultrasound treatment using phased array with geometric correction.
In the high-intensity focused ultrasound treatment of liver tumors, ultrasound propagation is affected by the rib cage. Because of the diffraction and absorption of the bone, the sound distribution at the focal plane is altered, and more importantly, overheating on the rib surface might occur. To overcome these problems, a geometric correction method is applied to turn off the elements blocked by the ribs. The potential of steering the focus of the phased-array along the propagation direction to improve the transcostal treatment was investigated by simulations and experiments using different rib models and transducers. The ultrasound propagation through the ribs was computed by a hybrid method including the Rayleigh-Sommerfeld integral, k-space method, and angular spectrum method. A modified correction method was proposed to adjust the output of elements based on their relative area in the projected "shadow" of the ribs. The simulation results showed that an increase in the specific absorption rate gain up to 300% was obtained by varying the focal length although the optimal value varied in each situation. Therefore, acoustic simulation is required for each clinical case to determine a satisfactory treatment plan.
Biomedical Instrument Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China.
Shan
S
Qiao
Guofeng
G
Shen
Jingfeng
J
Bai
Yazhu
Y
Chen
D000042:Absorption; D003198:Computer Simulation; D004867:Equipment Design; D057086:High-Intensity Focused Ultrasound Ablation / Q000295:instrumentation / Q000379:methods*; D008954:Models, Biological; D009038:Motion; D009716:Numerical Analysis, Computer-Assisted; D011312:Pressure; D012272:Ribs / Q000033:anatomy & histology*; D013016:Sound; D014159:Transducers