[Intraocular lens as a drug delivery device].
The development of an intraocular lens (IOL) as a drug delivery device has been the purpose of numerous preclinical studies and might become a future technology in cataract surgery. There are three techniques of pharmacological IOL modification: surface modification (coating), optic modification (soaking) or haptic modification with a slow-release-system. The therapeutic goals are endophthalmitis, postoperative inflammation and posterior capsule opacification.
Augenklinik, LMU München, Campus Innenstadt, Mathildenstr. 8, 80336, München, Deutschland, Kirsten.Eibl@med.uni-muenchen.de.
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Eibl-Lindner
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Liegl
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Wertheimer
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Kampik
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D058442:Capsule Opacification / Q000188:drug therapy*; D004343:Drug Implants / Q000008:administration & dosage*; D009877:Endophthalmitis / Q000188:drug therapy*; D006801:Humans; D007910:Lenses, Intraocular; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D011474:Prosthesis Design
D000893:Anti-Inflammatory Agents; D004343:Drug Implants; D009883:Ophthalmic Solutions