An ICT-based fluorescent switch-on probe for hydrogen sulfide in living cells.
An ICT-based fluorescent turn-on probe for hydrogen sulfide with high selectivity has been designed and synthesized. It exhibits up to 62-fold switch-on response toward H2S at given concentrations and can detect H2S in living cells with high sensitivity.
ZJU-ENS Joint Laboratory of Medicinal Chemistry, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. lixin81@zju.edu.cn.
Xin
X
Li
Shuai
S
Zhang
Ji
J
Cao
Nan
N
Xie
Tao
T
Liu
Bo
B
Yang
Qiaojun
Q
He
Yongzhou
Y
Hu
D000818:Animals; D002460:Cell Line; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000378:metabolism; D006862:Hydrogen Sulfide / Q000032:analysis* / Q000378:metabolism; D008264:Macrophages / Q000737:chemistry; D051379:Mice; D008856:Microscopy, Fluorescence; D013050:Spectrometry, Fluorescence
D005456:Fluorescent Dyes; D006862:Hydrogen Sulfide