Phytochemistry and medicinal properties of Phaleria macrocarpa (Scheff.) Boerl. extracts.
Phaleria macrocarpa, commonly known as Mahkota dewa is a medicinal plant that is indigenous to Indonesia and Malaysia. Extracts of P. macrocarpa have been used since years in traditional medicine that are evaluated scientifically as well. The extracts are reported for a number of valuable medicinal properties such as anti-cancer, anti-diabetic, anti-hyperlipidemic, anti-inflammatory, anti-bacterial, anti-fungal, anti-oxidant and vasorelaxant effect. The constituents isolated from different parts of P. macrocarpa include Phalerin, gallic acid, Icaricide C, magniferin, mahkoside A, dodecanoic acid, palmitic acid, des-acetylflavicordin-A, flavicordin-A, flavicordin-D, flavicordin-A glucoside, ethyl stearate, lignans, alkaloids andsaponins. The present review is an up-to-date summary of occurrence, botanical description, ethnopharmacology, bioactivity and toxicological studies related to P. macrocarpa.
Department of Pharmacology, School of Pharmaceutical Sciences, University Sains Malaysia, Minden, Pulau Pinang, Malaysia.
Rabia
R
Altaf
Mohammad Zaini Bin
MZ
Asmawi
Aidiahmad
A
Dewa
Amirin
A
Sadikun
Muhammad Ihtisham
MI
Umar
Gallic acid; God's crown; Mahkota dewa; magniferin; phalerin; thymelaceae