Changes in lipid density induce membrane curvature.
Highly curved bilayer lipid membranes make up the shell of many intra- and extracellular compartments, including organelles and vesicles. Using all-atom molecular dynamics simulations, we show that increasing the density of lipids in the bilayer membrane can induce the membrane to form a curved shape.
Department of Chemistry & Biochemistry and the BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303, USA.
Armando J
AJ
de Jesus
Noah
N
Kastelowitz
Hang
H
Yin