Impact of autologous blood transfusion on the use of pack of red blood cells in coronary artery bypass grafting surgery.
OBJECTIVE
To evaluate the impact of Cell Saver autologous blood transfusion system (CS) on the use of packed red blood cells (pRBC) in coronary artery bypass grafting (CABG) surgery.


METHODS
We carried out a retrospective cross-sectional study in 87 patients undergoing primary elective CABG with miniaturized cardiopulmonary bypass (miniCPB), divided in two groups: 44 without-CS and 43 with-CS. We investigated the necessity of absolute use and the volume of packed red blood cells (pRBC) in each group, as well as cardiovascular risk factors, presurgical variables and intraoperative surgical parameters. All data were collected from medical records and there was no randomization or intervention on group selection. Statistical analysis was performed with Student t-test, Mann-Whitney U-test and χ² test, with a 5% significance level.


RESULTS
There were no significant differences between the two groups in terms of cardiovascular risk factors and pre and intraoperative variables. Evaluating the absolute use of pRBC during surgery, there was a statistically significant difference (P=0.00008) between the groups without-CS (21/44 cases; 47.7%) and with-CS (4/43 cases; 9.3%). There was also a statistically significant difference (P=0.000117) in the volumes of pRBC between the groups without-CS (198.651258.65 ml) and with-CS (35.061125.67 ml). On the other hand, in the early postoperative period (up to 24h) there was no difference regarding either the absolute use or the volumes of pRBC between both studied groups.


CONCLUSIONS
Autologous erythrocyte transfusion with CS use reduces the use of intraoperative homologous pRBC in coronary artery bypass grafting surgeries associated with miniCPB.
University Hospital of Santa Maria (HUSM), Post-Graduate Program on Health Sciences, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil. leonardolms@gmail.com
Leonardo Leiria de Moura da
LL
Silva
Anna Júlia de Borba
AJ
Andres
Roberta
R
Senger
Ralf
R
Stuermer
Maria Celoni de Mello de
MC
Godoy
Eduardo Francisco Mafassioli
EF
Correa
Virgínia Maria
VM
Cóser
D000368:Aged; D001804:Blood Transfusion, Autologous; D001026:Coronary Artery Bypass / Q000379:methods*; D003430:Cross-Sectional Studies; D017707:Erythrocyte Transfusion / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D057725:Operative Blood Salvage; D012016:Reference Values; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D018709:Statistics, Nonparametric; D016896:Treatment Outcome