Hyaline vascular Castleman's disease involving the biliary tract.
We report a case of Castleman's Disease (CD), hyaline vascular subtype involving the biliary tract with obstruction. A 43 year old man presented with a 5 week history of abdominal and back pain with biliary obstructive symptoms. He was jaundiced with persistently high LFTs. Radiological investigation revealed a stricture in the extrahepatic biliary tract. The clinical impression at the time was of sclerosing cholangitis with bile duct cholangiocarcinoma. A Whipple's procedure was performed. Histology and immunohistochemistry supported the histologic diagnosis of CD of hyaline vascular subtype. There was no evidence of disease elsewhere and the patient was disease free after a 6 year follow-up. Our case describes the hyaline vascular subtype of CD, a relatively rare disease occurring in a previously undescribed location.
St Vincent's University Hospital, Elm Park, Dublin 4. kalimuthu.sangeetha@gmail.com
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Kalimuthu
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Traynor
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Albores-Saavedra
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K
Sheahan
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Gibbons
D000328:Adult; D017734:Bile Ducts, Extrahepatic / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D005871:Castleman Disease / Q000175:diagnosis* / Q000601:surgery; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods; D001651:Cholestasis, Extrahepatic / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D006818:Hyalin; D008297:Male; D016577:Pancreaticoduodenectomy; D016896:Treatment Outcome