Matching the power of high throughput screening to the chemical diversity of natural products.
Covering up to 2013. Application of high throughput screening technologies to natural product samples demands alterations in assay design as well as sample preparation in order to yield meaningful hit structures at the end of the campaign.
Basic Science Program, SAIC-Frederick, Inc., Frederick National Lab, Frederick, MD 21702, USA. henrichcj@mail.nih.gov.
Curtis J
CJ
Henrich
John A
JA
Beutler
D001688:Biological Products / Q000494:pharmacology; D015195:Drug Design
D001688:Biological Products