Macular findings in healthy full-term Hispanic newborns observed by hand-held spectral-domain optical coherence tomography.
OBJECTIVE
To enhance understanding of ethnically diverse normal newborn retinal morphology, the authors report spectral-domain optical coherence tomography (SD-OCT) macular findings in healthy Hispanic newborns.


METHODS
In this IRB-approved prospective, observational case series, 20 full-term Hispanic newborns had dilated retinal examinations and imaging by hand-held SD-OCT without sedation at the Duke Birthing Center.


RESULTS
Of 20 newborns imaged (35% male; median gestational age: 39 weeks; range: 36 to 40 weeks), two (10%) had bilateral subfoveal fluid, including one case of bilateral double subretinal fluid pockets. Three eyes of two infants (10%) had retinal macular cystoid structures (one enlarged at 1.5 months, with resolution by 3 months). These SD-OCT findings were not visible by indirect ophthalmoscopy.


CONCLUSIONS
Some Hispanic newborns have subretinal fluid or macular cystoid structures on SD-OCT. This study expands our understanding of findings seen by SD-OCT in healthy full-term newborns of various races.
Michelle T
MT
Cabrera
Rachelle V
RV
O'Connell
Cynthia A
CA
Toth
Ramiro S
RS
Maldonado
Du
D
Tran-Viet
Michael J
MJ
Allingham
Stephanie J
SJ
Chiu
Sina
S
Farsiu
Gabriela M
GM
Maradiaga Panayotti
Geeta K
GK
Swamy
Sharon F
SF
Freedman
D005260:Female; D005584:Fovea Centralis / Q000473:pathology; D006630:Hispanic or Latino; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D019095:Point-of-Care Systems; D011446:Prospective Studies; D012164:Retinal Diseases / Q000175:diagnosis / Q000208:ethnology; D058471:Subretinal Fluid; D047929:Term Birth / Q000502:physiology*; D041623:Tomography, Optical Coherence / Q000379:methods*