Mechanical strength and biocompatibility of ultrafine-grained commercial purity titanium.
The effect of grain refinement of commercial purity titanium by equal channel angular pressing (ECAP) on its mechanical performance and bone tissue regeneration is reported. In vivo studies conducted on New Zealand white rabbits did not show an enhancement of biocompatibility of ECAP-modified titanium found earlier by in vitro testing. However, the observed combination of outstanding mechanical properties achieved by ECAP without a loss of biocompatibility suggests that this is a very promising processing route to bioimplant manufacturing. The study thus supports the expectation that commercial purity titanium modified by ECAP can be seen as an excellent candidate material for bone implants suitable for replacing conventional titanium alloy implants.
Centre for Advanced Hybrid Materials, Department of Materials Engineering, Monash University, Clayton, VIC 3800, Australia. yuri.estrin@monash.edu
Yuri
Y
Estrin
Hyoun-Ee
HE
Kim
Rimma
R
Lapovok
Hoi Pang
HP
Ng
Ji-Hoon
JH
Jo
D000818:Animals; D001672:Biocompatible Materials; D008422:Materials Testing; D055595:Mechanical Phenomena; D010006:Osteoblasts / Q000502:physiology; D019736:Prostheses and Implants; D011817:Rabbits; D013499:Surface Properties; D014025:Titanium
D001672:Biocompatible Materials; D014025:Titanium