Liver transplantation after severe hepatic trauma: a sustainable practice. A single-center experience and review of the literature.
Severe hepatic trauma is a rare indication for liver transplantation (LT). We report our single-center experience of LT for hepatic trauma. Four new cases are discussed in light of a literature review in order to depict the pathways leading from hepatic trauma to LT and to assess the outcomes of this practice. LT is generally indicated in case of uncontrollable hemorrhage, acute liver failure, or post-traumatic late sequelae. Hepatic vessels thrombosis, sepsis, major hepatic resections, and a late referral are factors associated with the progression toward irreversible liver failure. Considering all reported cases, early patient and graft survival reached 68% and 62%, respectively, but in the last decade both have improved to 84%. LT after severe hepatic trauma is a sustainable practice considering the current good outcomes and the ineluctable death of these patients without LT.
General Surgery 8 and Liver Transplantation Center, San Giovanni Battista - Molinette University Hospital, A. O. Città della Salute e della Scienza, Turin, Italy.
Damiano
D
Patrono
Andrea
A
Brunati
Renato
R
Romagnoli
Mauro
M
Salizzoni
D000293:Adolescent; D000328:Adult; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D055815:Young Adult; D006085:Graft Survival; D008099:Liver / Q000293:injuries / Q000601:surgery; D017093:Liver Failure / Q000601:surgery; D016031:Liver Transplantation; D011183:Postoperative Complications; D011379:Prognosis; D012196:Review Literature as Topic; D002986:Clinical Trials as Topic
hemorrhage; liver failure; liver transplantation; sepsis; thrombosis