Representation of frequency-modulated sounds in the human brain.
Frequency-modulation is a ubiquitous sound feature present in communicative sounds of various animal species and humans. Functional imaging of the human auditory system has seen remarkable advances in the last two decades and studies pertaining to frequency-modulation have centered around two major questions: a) are there dedicated feature-detectors encoding frequency-modulation in the brain and b) is there concurrent representation with amplitude-modulation, another temporal sound feature? In this review, we first describe how these two questions are motivated by psychophysical studies and neurophysiology in animal models. We then review how human non-invasive neuroimaging studies have furthered our understanding of the representation of frequency-modulated sounds in the brain. Finally, we conclude with some suggestions on how human neuroimaging could be used in future studies to address currently still open questions on this fundamental sound feature. This article is part of a Special Issue entitled Human Auditory Neuroimaging.
Human Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan; Career-Path Promotion Unit for Young Life Scientists, Kyoto University, Kyoto 606-8501, Japan. Electronic address: altmann@cp.kyoto-u.ac.jp.
Christian F
CF
Altmann
Bernhard H
BH
Gaese
D000161:Acoustic Stimulation; D000818:Animals; D001303:Auditory Cortex / Q000033:anatomy & histology / Q000502:physiology*; D001306:Auditory Pathways / Q000502:physiology; D001307:Auditory Perception; D001522:Behavior, Animal; D001931:Brain Mapping / Q000379:methods; D006801:Humans; D023421:Models, Animal; D011571:Psychoacoustics; D013997:Time Factors
AM; BOLD; EEG; FM; IC; MEG; MMF; MMN; MVPA; PET; PT; STG; aSSR; amplitude modulation; auditory steady-state responses; blood oxygenation level-dependent; electroencephalography; frequency modulation; inferior colliculus; magnetoencephalography; mismatch field; mismatch negativity; multivariate pattern analysis; planum temporale; positron emission tomography; superior temporal gyrus