[Flavonoids from Humulus lupulus].
Nine compounds were isolated and purified by column chromatographic techniques including macroporous resin, silica gel, ODS, Sephadex LH-20, and preparative reversed-phase HPLC. Their structures were elucidated as taxifolin (1), naringenin (2), chalconaringenin (3), acacetin (4), quercetin 3-O-beta-D-galactopyranoside (5), 6-prenylnaringenin (6) xanthohumol (7), desmethylxanthohumol (8), xanthohumol B (9) on the basis of MS and NMR spectroscopic data analysis. Compounds 1-5 were isolated from Humulus lupulus for the first time.
Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China. cpuzwk@163.com
Wei-Ku
WK
Zhang
Shou-Bao
SB
Wang
Cheng-Yu
CY
Fu
Ping
P
Li
Jie-Kun
JK
Xu
D003911:Dextrans / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D044950:Flavanones / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry*; D027582:Humulus / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D011794:Quercetin / Q000031:analogs & derivatives / Q000737:chemistry
D003911:Dextrans; D004365:Drugs, Chinese Herbal; D044950:Flavanones; D005419:Flavonoids; C025614:sephadex; D011794:Quercetin; C003377:taxifolin; C005273:naringenin