The role of magnetic nanoparticles in the localization and treatment of breast cancer.
The role of magnetic nanoparticles (MNPs) in medical applications is rapidly developing. Advances in nanotechnology are bringing us closer to the development of dual and multifunctional nanoparticles that are challenging the traditional distinction between diagnostic and treatment agents. The current use of MNPs in breast cancer falls into four main groups: (1) imaging of primary and metastatic disease, (2) sentinel lymph node biopsy (SLNB), (3) drug delivery systems, and (4) magnetic hyperthermia. The current evidence for the use of MNPs in these fields is mounting, and potential cutting-edge clinical applications, particularly with relevance to the fields of breast oncological surgery, are emerging.
Department of Research Oncology, King's College London, Guy's Hospital Campus, Great Maze Pond, London, UK. muneer.ahmed@kcl.ac.uk
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D001943:Breast Neoplasms / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D003952:Diagnostic Imaging; D016503:Drug Delivery Systems; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D058185:Magnetite Nanoparticles / Q000008:administration & dosage* / Q000627:therapeutic use; D021701:Sentinel Lymph Node Biopsy
D058185:Magnetite Nanoparticles