Isolation and molecular characterization of Fikirini rhabdovirus, a novel virus from a Kenyan bat.
Zoonotic and vector-borne pathogens have comprised a significant component of emerging human infections in recent decades, and bats are increasingly recognized as reservoirs for many of these disease agents. To identify novel pathogens associated with bats, we screened tissues of bats collected in Kenya. Virus isolates were identified by next generation sequencing of viral nucleic acid preparations from the infected cell culture supernatant and characterized. Here we report the identification of Fikirini rhabdovirus, a novel rhabdovirus isolated from a bat, Hipposideros vittatus, captured along the Kenyan coast.
Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Arbovirus Diseases Branch, Fort Collins, CO, USA.
Rebekah C
RC
Kading
Centers for Disease Control and Prevention, Division of High Consequence Pathogens and Pathology, Poxvirus and Rabies Branch, Atlanta, GA, USA.
Amy T
AT
Gilbert
Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Arbovirus Diseases Branch, Fort Collins, CO, USA.
Eric C
EC
Mossel
Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Arbovirus Diseases Branch, Fort Collins, CO, USA.
Mary B
MB
Crabtree
Centers for Disease Control and Prevention, Division of High Consequence Pathogens and Pathology, Poxvirus and Rabies Branch, Atlanta, GA, USA.
Ivan V
IV
Kuzmin
Centers for Disease Control and Prevention, Division of High Consequence Pathogens and Pathology, Poxvirus and Rabies Branch, Atlanta, GA, USA.
Michael
M
Niezgoda
National Museums of Kenya, Nairobi, Kenya.
Bernard
B
Agwanda
University of Pretoria, Department of Microbiology and Plant Pathology, Pretoria, South Africa.
Wanda
W
Markotter
Centers for Disease Control and Prevention, Office of Infectious Disease, National Center for Emerging and Zoonotic Infectious Diseases, Atlanta, GA, USA.|SRA International, Atlanta, GA, USA.
M Ryan
MR
Weil
Centers for Disease Control and Prevention, Global Disease Detection Program, Nairobi, Kenya.
Joel M
JM
Montgomery
Centers for Disease Control and Prevention, Division of High Consequence Pathogens and Pathology, Poxvirus and Rabies Branch, Atlanta, GA, USA.
Charles E
CE
Rupprecht
Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Arbovirus Diseases Branch, Fort Collins, CO, USA.
Barry R
BR
Miller
D000818:Animals; D002685:Chiroptera / Q000821:virology*; D004197:Disease Reservoirs / Q000821:virology; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods; D007630:Kenya; D008099:Liver / Q000821:virology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D012209:Rhabdoviridae / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D018353:Rhabdoviridae Infections / Q000662:veterinary* / Q000821:virology; D017422:Sequence Analysis, DNA / Q000379:methods
D012367:RNA, Viral