Endoscopic swept-source optical coherence tomography based on a two-axis microelectromechanical system mirror.
A microelectromechanical system (MEMS) mirror based endoscopic swept-source optical coherence tomography (SS-OCT) system that can perform three-dimensional (3-D) imaging at high speed is reported. The key component enabling 3-D endoscopic imaging is a two-axis MEMS scanning mirror which has a 0.8×0.8  mm2 mirror plate and a 1.6×1.4  mm2 device footprint. The diameter of the endoscopic probe is only 3.5 mm. The imaging rate of the SS-OCT system is 50  frames/s. OCT images of both human suspicious oral leukoplakia tissue and normal buccal mucosa were taken in vivo and compared. The OCT imaging result agrees well with the histopathological analysis.
University of Shanghai for Science and Technology, Ministry of Education, Shanghai Key Lab of Modern Optical System, Engineering Research Center of Optical Instrument and System, No. 516 JunGong Road, Shanghai 200093, China.
Donglin
D
Wang
Linlai
L
Fu
Xin
X
Wang
Zhongjian
Z
Gong
Sean
S
Samuelson
Can
C
Duan
Hongzhi
H
Jia
Jun Shan
JS
Ma
Huikai
H
Xie
D019723:Endoscopes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation*; D007909:Lenses; D008029:Lighting / Q000295:instrumentation*; D055617:Micro-Electrical-Mechanical Systems / Q000295:instrumentation*; D008904:Miniaturization; D009062:Mouth Neoplasms / Q000473:pathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000295:instrumentation*