The hemodynamic effects of spinal block with low dose of bupivacaine and sufentanil in patients with low myocardial ejection fraction.
The aim of this study was to assess the effect of spinal block with low dose of bupivacaine and sufentanil on patients with low cardiac output who underwent lower limb surgery. Fifteen patients who had ejection fraction less than 40% (group 1) were compared with 65 cases with ejection fraction more than 40% (group 2) in our study. Our subjects underwent spinal block with 7.5 mg hyperbaric bupivacaine 0.5% and 5 µg sufentanil. We recorded early events such as hypotension, bradycardia, vasopressor need and ST segment change in our cases. The average mean arterial pressure decreased 13% (110 mmHg to 95.7 mmHg) in group 1 and 20% (160 mmHg to 128 mmHg) in group 2 (P&lt;0.001). Hypotension due to spinal anesthesia was observed in none of our subjects in both groups and none of our cases need to vasopressor support. All patients remained alert, and no ST segment changes were observed in two groups. In our study none of subjects complained of pain intraoperatively. The subjects were without complaints during the spinal anesthetic in both groups. Spinal block with low dose local anesthetic and sufentanil was a safe and effective method for lower limb surgery in patients with low ejection fraction.
Department of Anesthesiology, Razi Hospital AND Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mehdi
M
Sanatkar
Mostafa
M
Sadeghi
Nafiseh
N
Esmaeili
Hossein
H
Sadrossadat
Mehrdad
M
Shoroughi
Shahrokh
S
Ghazizadeh
Ebrahim
E
Khoshraftar
Hassan
H
Pour Anvari
Nasim
N
Alipour
D000368:Aged; D000369:Aged, 80 and over; D000701:Analgesics, Opioid / Q000494:pharmacology*; D000775:Anesthesia, Spinal / Q000379:methods*; D000779:Anesthetics, Local / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D002045:Bupivacaine / Q000494:pharmacology*; D016022:Case-Control Studies; D006801:Humans; D035002:Lower Extremity / Q000601:surgery; D008875:Middle Aged; D013318:Stroke Volume; D017409:Sufentanil / Q000494:pharmacology*
D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D017409:Sufentanil; D002045:Bupivacaine