Underwater-transparent nanodendritic coatings for directly monitoring cancer cells.
Underwater-transparent nanodendritic coatings are easily fabricated by a three-step template process. After modification with anti-EpCAM, the coatings exhibit the capability for efficiently capturing rare number of cancer cells from whole blood. On the other hand, the unique underwater transparency enables the coatings to directly monitor captured cancer cells by optical imaging.
Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China; University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Gao
G
Yang
Hongliang
H
Liu
Xueli
X
Liu
Pengchao
P
Zhang
Chao
C
Huang
Tailin
T
Xu
Lei
L
Jiang
Shutao
S
Wang
D000818:Animals; D000906:Antibodies / Q000737:chemistry; D000951:Antigens, Neoplasm / Q000737:chemistry*; D002448:Cell Adhesion; D015815:Cell Adhesion Molecules / Q000737:chemistry*; D045744:Cell Line, Tumor; D002469:Cell Separation / Q000379:methods*; D000071858:Epithelial Cell Adhesion Molecule; D006801:Humans; D061986:MCF-7 Cells; D008422:Materials Testing; D049329:Nanostructures / Q000737:chemistry*; D061848:Optical Imaging; D051381:Rats; D012822:Silicon Dioxide / Q000737:chemistry; D013499:Surface Properties; D014867:Water
D000906:Antibodies; D000951:Antigens, Neoplasm; D015815:Cell Adhesion Molecules; C499379:EPCAM protein, human; D000071858:Epithelial Cell Adhesion Molecule; D014867:Water; D012822:Silicon Dioxide
cancer cells; optical monitoring; surface coating; underwater transparency