Lophomonas blattarum and bronchopulmonary disease.
The natural habitat of the multiflagellate protozoon Lophomonas blattarum is as an endocommensal in the hindgut of insects such as cockroaches. However, it also causes bronchopulmonary disease in humans. The aim of this paper was to review the literature on this organism in the context of respiratory disease. The biology epidemiology, route of transmission, pathogenic mechanisms and diagnosis methods are also described. A total of 61 cases were identified in the literature. The majority of these reports were from China, with some cases from Peru and Spain. Most cases were adult males, although paediatric cases were reported in Peru. Clinical presentation was non-specific, including symptoms such as fever, cough and breathless. Antiprotozoal therapy was generally effective.
Protozoal Respiratory Pathology Research Unit. Fundación INCLÍNICA, Calvo Sotelo, 16-3 dcha, 33007-Oviedo, Spain.
Rafael
R
Martinez-Girón
Institute of Primary Care & Public Health, Cardiff University School of Medicine, Neuadd Meirionnydd, Heath Park, Cardiff CF14 4YS, UK.
Hugo
H
Cornelis van Woerden
D000818:Animals; D002681:China / Q000453:epidemiology; D003058:Cockroaches / Q000469:parasitology; D006801:Humans; D008174:Lung Diseases, Parasitic / Q000453:epidemiology* / Q000469:parasitology / Q000473:pathology* / Q000635:transmission; D056900:Parabasalidea / Q000302:isolation & purification*; D010568:Peru / Q000453:epidemiology; D011528:Protozoan Infections / Q000453:epidemiology* / Q000469:parasitology / Q000473:pathology* / Q000635:transmission; D013030:Spain / Q000453:epidemiology