Polyacrylamide phantom for self-actuating needle-tissue interaction studies.
This study presents a polyacrylamide gel as a phantom material for needle insertion studies specifically developed for self-actuating needles to enhance the precise placement of needles in prostate. Bending of these self-actuating needles within tissue is achieved by Nitinol actuators attached to the needle body; however these actuators usually involve heating that can thermally damage the tissue surrounding the needles. Therefore, to develop and access feasibility of these needles, a polyacrylamide gel has been developed that mimics the thermal damage and mechanical properties of prostate tissue. Mechanical properties of the polyacrylamide gel was controlled by varying the concentrations of acrylamide monomer and N,N-methylene-bisacrylamide (BIS) cross-linker, and thermal sensitivity was achieved by adding bovine serum albumin (BSA) protein. Two polyacrylamide gels with different concentrations were developed to mimic the elastic modulus of the tissue. The two phantoms showed different rupture toughness and different deflection of bevel-tip needle. To study the thermal damage, a Nitinol wire was embedded in the phantom and resistively heated. The measured opaque zone (0.40mm) formed around the wire was close to the estimated damage zone (0.43mm) determined using the cumulative equivalent minutes at 43°C.
Department of Mechanical Engineering, Temple University, 1947 North 12th Street, Philadelphia, PA 19122, United States.
Naresh V
NV
Datla
Department of Mechanical Engineering, Temple University, 1947 North 12th Street, Philadelphia, PA 19122, United States.
Bardia
B
Konh
Department of Mechanical Engineering, Temple University, 1947 North 12th Street, Philadelphia, PA 19122, United States.
Joe J Y
JJ
Koo
Department of Mechanical Engineering, Temple University, 1947 North 12th Street, Philadelphia, PA 19122, United States.
Daniel J W
DJ
Choi
Department of Radiation Oncology, Thomas Jefferson University, 111 South 11th Street, Philadelphia, PA 19107, United States.
Yan
Y
Yu
Department of Radiation Oncology, Thomas Jefferson University, 111 South 11th Street, Philadelphia, PA 19107, United States.
Adam P
AP
Dicker
Departments of Radiation Oncology, University Hospitals, Case Western Reserve University, Cleveland, OH 44106, United States.
Tarun K
TK
Podder
Department of Mechanical Engineering, Temple University, 1947 North 12th Street, Philadelphia, PA 19122, United States.
Kurosh
K
Darvish
Department of Mechanical Engineering, Temple University, 1947 North 12th Street, Philadelphia, PA 19122, United States. Electronic address: hutapea@temple.edu.
Parsaoran
P
Hutapea
D000180:Acrylic Resins / Q000737:chemistry; D000818:Animals; D002417:Cattle; D055119:Elastic Modulus; D005240:Feasibility Studies; D008297:Male; D009339:Needles; D019047:Phantoms, Imaging; D011467:Prostate / Q000166:cytology*; D012710:Serum Albumin, Bovine / Q000737:chemistry; D013696:Temperature; D000099166:Polyacrylamides
D000180:Acrylic Resins; D012710:Serum Albumin, Bovine; D000099166:Polyacrylamides
Phantom; Polyacrylamide; Prostate; Self-actuating needle; Thermal damage