[Digestive insufficiency of the stomach in children from the positions of clinical morphology and its role in the assessment of the indications for nutritional support ].
The structure of gastric mucosa (GM) of the stomach fundus (SF) was studied in children with various gastrointestinal diseases. In children, the main structural parameters of the SF (GM thickness, depth of glands and thickness of the mucosal epithelium area) varied widely (3.5-5.3 times). The following ranges were allocated: hypotrophy ("atrophy"), eutrophy (area of mean values) and hypertrophy of SF GM thickness, depth of the glands and thickness of the mucosal epithelium area. Hypotrophy ("atrophy") of the SF glands was found in approximately one third of the children of different age which could lead to decrease in the digestive function of the stomach and cause specific clinical symptoms of dyspepsia. Atrophic changes of SF GM were observed in children of all age groups. Most often (49%), fundic glands hypotrophy was observed in children of early age. With age, the incidence of atrophic changes of SF GM decreased. Atrophic changes in the GM can be detected during microanatomical or histopathological (using morphometry) examination of the SF.
Iu A
IuA
Lysikov
T A
TA
Malitsyna
A V
AV
Krasavin
L N
LN
Tsvetkova
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004063:Digestion / Q000502:physiology*; D004066:Digestive System Diseases / Q000150:complications / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D005753:Gastric Mucosa / Q000503:physiopathology / Q000648:ultrastructure; D005757:Gastritis, Atrophic / Q000150:complications / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D005758:Gastritis, Hypertrophic / Q000150:complications / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007223:Infant; D018529:Nutritional Support; D009929:Organ Size / Q000502:physiology; D013270:Stomach / Q000473:pathology* / Q000503:physiopathology