Proton magnetic resonance spectroscopy: technique for the neuroradiologist.
Magnetic resonance spectroscopy (MRS) provides information on neuronal and axonal viability, energetics of cellular structures, and status of cellular membranes. Proton MRS appeals to clinicians and scientists because its application in the clinical setting can increase the specificity of MR imaging. The objective of this article is to provide descriptive concepts of the technique and its application in vivo for a variety of patient populations. When appropriately incorporating MRS into the neuroradiologic evaluation, this technique produces relevant information to radiologists and clinicians for their understanding of adult and pediatric neurologically based disease processes.
Department of Radiology, Pediatrics, Neuroscience and Environmental Health, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. kim.cecil@cchmc.org
Kim M
KM
Cecil
D015415:Biomarkers / Q000378:metabolism*; D001704:Biopolymers / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D001927:Brain Diseases / Q000175:diagnosis* / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009656:North America; D011522:Protons
D015415:Biomarkers; D001704:Biopolymers; D011522:Protons
Chemical shift; Localization; Metabolite; Shimming; Spectral dispersion; Suppression