Bone dissemination of prostate cancer after holmium laser enucleation of the prostate: a case report and a review of the literature.
We report a case of dissemination of prostate cancer after holmium laser enucleation of the prostate in an 80-year-old patient. The patient presented at hospital because of nocturia. Transrectal ultrasound-guided biopsy was carried out because of high serum prostate-specific antigen (3.55 ng/mL), but it showed no malignancies. Benign prostate hyperplasia was diagnosed, and he was started on an α1-blocker. Although the urinary symptom improved with silodosin, acute urinary retention occurred 3 years after therapy began. Holmium laser enucleation of the prostate for relief of bladder outlet obstruction enabled discharge of urine. Pathological examination of the resected tissue found adenocarcinoma with a high Gleason score, 4 + 5. Serum alkaline phosphatase increased rapidly after holmium laser enucleation, and bone scintigraphy confirmed multiple bone metastases. Prostate cancer, T1bN0M1b, was diagnosed.
Department of Urology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Dai
D
Koguchi
Morihiro
M
Nishi
Takefumi
T
Satoh
Toshiya
T
Shitara
Kazumasa
K
Matsumoto
Tetsuo
T
Fujita
Kazunari
K
Yoshida
Masatsugu
M
Iwamura
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery*; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects*; D053844:Lasers, Solid-State; D008297:Male; D011468:Prostatectomy / Q000009:adverse effects; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery*; D011877:Radionuclide Imaging; D001748:Urinary Bladder Neck Obstruction / Q000473:pathology / Q000601:surgery
dissemination; holmium laser enucleation of the prostate; prostate cancer