Successful nonoperative management of the most severe blunt renal injuries: a multicenter study of the research consortium of New England Centers for Trauma.
OBJECTIVE
Severe renal injuries after blunt trauma cause diagnostic and therapeutic challenges for the treating clinicians. The need for an operative vs a nonoperative approach is debated.


OBJECTIVE
To determine the rate, causes, predictors, and consequences of failure of nonoperative management (NOM) in grade IV and grade V blunt renal injuries (BRIs).


METHODS
Retrospective case series.


METHODS
Twelve level I and II trauma centers in New England.


METHODS
A total of 206 adult patients with a grade IV or V BRI who were admitted between January 1, 2000, and December 31, 2011.


METHODS
Failure of NOM, defined as the need for a delayed operation or death due to renal-related complications during NOM.


RESULTS
Of 206 patients, 52 (25.2%) were operated on immediately, and 154 (74.8%) were managed nonoperatively (with the assistance of angiographic embolization for 25 patients). Nonoperative management failed for 12 of the 154 patients (7.8%) and was related to kidney injury in 10 (6.5%). None of these 10 patients had complications because of the delay in BRI management. The mean (SD) time from admission to failure was 17.6 (27.4) hours (median time, 7.5 hours; range, 4.5-102 hours), and the cause was hemodynamic instability in 10 of the 12 patients (83.3%). Multivariate analysis identified 2 independent predictors of NOM failure: older than 55 years of age and a road traffic crash as the mechanism of injury. When both risk factors were present, NOM failure occurred for 27.3% of the patients; when both were absent, there were no NOM failures. Of the 142 patients successfully managed nonoperatively, 46 (32.4%) developed renal-related complications, including hematuria (24 patients), urinoma (15 patients), urinary tract infection (8 patients), renal failure (7 patients), and abscess (2 patients). These patients were managed successfully with no loss of renal units (ie, kidneys). The renal salvage rate was 76.2% for the entire population and 90.3% among patients selected for NOM.


CONCLUSIONS
Hemodynamically stable patients with a grade IV or V BRI were safely managed nonoperatively. Nonoperative management failed for only 6.5% of patients owing to renal-related injuries, and three-fourths of the entire population retained their kidneys.
Department of Surgery, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts.
Gwendolyn M
GM
van der Wilden
George C
GC
Velmahos
D'Andrea K
DK
Joseph
Lenworth
L
Jacobs
M George
MG
Debusk
Charles A
CA
Adams
Ronald
R
Gross
Barbara
B
Burkott
Suresh
S
Agarwal
Adrian A
AA
Maung
Dirk C
DC
Johnson
Jonathan
J
Gates
Edward
E
Kelly
Yvonne
Y
Michaud
William E
WE
Charash
Robert J
RJ
Winchell
Steven E
SE
Desjardins
Michael S
MS
Rosenblatt
Sanjay
S
Gupta
Miguel
M
Gaeta
Yuchiao
Y
Chang
Marc A
MA
de Moya
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007668:Kidney / Q000293:injuries*; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma; D009511:New England / Q000453:epidemiology; D012189:Retrospective Studies; D016879:Salvage Therapy; D013997:Time Factors; D014193:Trauma Centers; D015599:Trauma Severity Indices; D016896:Treatment Outcome; D014949:Wounds, Nonpenetrating / Q000145:classification / Q000401:mortality / Q000601:surgery / Q000628:therapy*