Cemented versus uncemented hemiarthroplasty for femoral neck fractures in elderly patients: a meta-analysis.
OBJECTIVE
Controversy still exists regarding using cemented or uncemented hemiarthroplasty for femoral neck fractures in elderly patients. The aim of this study is to compare the effectiveness and safety of the two surgical techniques in femoral neck fracture patients over 70 years old.


METHODS
We searched PUBMED, EMBASE, Cochrane Library, CNKI and VIP Database from inception to December 2012 for relevant randomized controlled trials (RCTs). Outcomes of interest include postoperative hip function, residue pain, complication rates, mortality, reoperation rate, operation time and intraoperative blood loss. Odds ratios (OR) and weighted mean differences (WMD) from each trial were pooled using random-effects model or fixed-effects model given on the heterogeneity of the included studies.


RESULTS
7 RCTs involving 1,125 patients (1,125 hips) were eligible for meta-analysis. Our results demonstrate that cemented hemiarthroplasty is associated with better postoperative hip function (OR = 0.48, 95% CI, 0.31-0.76; P = 0.002), lower residual pain (OR = 0.43, 95%CI, 0.29-0.64; P<0.0001), less implant-related complications (OR = 0.15, 95%CI, 0.09-0.26; P<0.00001) and longer operation time (WMD = 7.43 min, 95% CI, 5.37-9.49 min; P<0.00001). No significant difference was observed between the two groups in mortality, cardiovascular and cerebrovascular complications, local complications, general complications, reoperation rate and intraoperative blood loss.


CONCLUSIONS
Compared with uncemented hemiarthroplasty, the existing evidence indicates that cemented hemiarthroplasty can achieve better hip function, lower residual pain and less implant-related complications with no increased risk of mortality, cardiovascular and cerebrovascular complications, general complications, local complications and reoperation rate in treating elderly patients with femoral neck fractures.
Department of Orthopaedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, China.
Tao
T
Li
Qianyu
Q
Zhuang
Xisheng
X
Weng
Lei
L
Zhou
Yanyan
Y
Bian
D000368:Aged; D015982:Bias; D016063:Blood Loss, Surgical; D001843:Bone Cements / Q000494:pharmacology*; D016001:Confidence Intervals; D005265:Femoral Neck Fractures / Q000601:surgery*; D062785:Hemiarthroplasty / Q000009:adverse effects; D006615:Hip / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007430:Intraoperative Care; D016017:Odds Ratio; D011182:Postoperative Care; D011183:Postoperative Complications / Q000209:etiology; D012086:Reoperation; D018570:Risk Assessment; D013997:Time Factors
D001843:Bone Cements