Discrepancy in ABO blood grouping.
Discrepancies in blood typing is one of the major reasons in eliciting a transfusion reaction. These discrepancies can be avoided through detailed analysis for the blood typing. Here, we report a subgroup of blood group type-B in the ABO system. Donor's blood was analyzed by employing commercial antisera for blood grouping. The results of forward (known antisera) and reverse (known antigen) reaction were not complimentary. A detailed analysis using the standard protocols by American Association of Blood Banking revealed the blood type as a variant of blood group-B instead of blood group-O. This is suggestive of the fact that blood group typing should be performed with extreme care and any divergence, if identified, should be properly resolved to avoid transfusion reactions. Moreover, a major study to determine the blood group variants in Pakistani population is needed.
Department of Physiology, University of Karachi, Karachi, Pakistan.
Mohammad Noman
MN
Khan
Taseer Ahmed
TA
Khan
Zulfiqar
Z
Ahmed
D000017:ABO Blood-Group System; D000328:Adult; D044466:Asian People; D001782:Blood Donors; D001787:Blood Group Incompatibility / Q000517:prevention & control*; D001788:Blood Grouping and Crossmatching; D006801:Humans; D008297:Male
D000017:ABO Blood-Group System