Toxic pyrrolizidinalkaloids as undesired contaminants in food and feed: degradation of the PAs from Senecio jacobaea in silage.
Pyrrolizidine alkaloids (PAs) can show a hazardous potential for men and animals. They can act as cancerogenic, mutagenic, teratogenic and fetotoxic agents. One pathway of a human intoxication is its occurence as contaminants in food and feed. Here, the contamination of cereals already led to severe and fatal intoxication episodes. Besides this, milk is of special concern as it is the main food for children which show a very high susceptibility for a PA intoxication. Milk can contain PAs in case the milk producing animals have access to contaminated feed. In this context it is of special interest whether the PA content of contaminated silage remains stable during the ensiling procedure or show a more or less high level of decomposition. We could show that ensiling will not lead to PA-free silage.
Pharmazeutisches Institut der Universität, Bonn, Germany.
J
J
Becerra-Jiminez
M
M
Kuschak
E
E
Roeder
H
H
Wiedenfeld
D000821:Animal Feed / Q000032:analysis*; D000818:Animals; D005504:Food Analysis; D005506:Food Contamination / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D008129:Lolium / Q000737:chemistry; D008892:Milk / Q000737:chemistry; D011763:Pyrrolizidine Alkaloids / Q000032:analysis* / Q000633:toxicity*; D012015:Reference Standards; D012674:Senecio / Q000737:chemistry*; D012820:Silage / Q000032:analysis*
D011763:Pyrrolizidine Alkaloids