Magnetic resonance spectroscopy in metabolic disorders.
Magnetic resonance spectroscopy (MRS) is a powerful clinical tool for investigating the metabolic characteristics of neurologic diseases. Proton ((1)H)-MRS is the most commonly used and widely available method. In this article, a brief introduction regarding technical issues of (1)H-MRS applied to the study of metabolic diseases is followed by a description of findings in some of the most common entities in this large, heterogeneous group of neurologic disorders. The aim was to provide a focused representation of the most common applications of (1)H-MRS to metabolic disorders in a routine clinical setting.
Pediatric Neuroradiology Unit, Istituto Giannina Gaslini, Genoa 16147, Italy. andrearossi@ospedale-gaslini.ge.it
Andrea
A
Rossi
Roberta
R
Biancheri
D015415:Biomarkers / Q000378:metabolism*; D001704:Biopolymers / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D001928:Brain Diseases, Metabolic; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
D015415:Biomarkers; D001704:Biopolymers
Hypomyelination; Leukodystrophy; Leukoencephalopathy; MR spectroscopy; Metabolic diseases; White matter