Association of preoperative obstructive jaundice with postoperative infectious complications following pancreaticoduodenectomy.
OBJECTIVE
The aim of this study was to evaluate the effects of obstructive jaundice on Infectious Complications of the patients who underwent pancreaticoduodenectomy.


METHODS
One-hundred and sixteen consecutive patients without preoperative biliary drainage underwent pancreaticoduodenectomy from January 2006 to April 2010 and their data of post-operative complication were analyzed. Different level of bilirubin and different times of jaundice on infectious complications of the patients underwent pancreaticoduodenectomy were analysis.


RESULTS
Patients with severe jaundice (Total bilirubin ≥5 mg/dL; n = 55), had a higher incidence in subsequent infectious complications than the patients with total bilirubin level of less than 5 mg/dL (n = 61) (36.06% vs. 56.36%, p <0.05). The patients with preoperative TB level of 5 or more sub classified according to the duration of jaundice. However, two groups without statistical significance in terms of post-operative complications. There were no significant differences in post-operative mortality rate among the different groups.


CONCLUSIONS
The elevated serum bilirubin increases the rate of infectious complications of the patients underwent pancreaticoduodeneotomy.
Sizhen
S
Wang
Xinbo
X
Wang
Liang
L
Li
Hongshan
H
Dai
Jianming
J
Han
D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000209:etiology*; D001663:Bilirubin / Q000097:blood; D005260:Female; D006801:Humans; D041781:Jaundice, Obstructive / Q000150:complications*; D008297:Male; D008875:Middle Aged; D016577:Pancreaticoduodenectomy / Q000009:adverse effects* / Q000401:mortality; D011183:Postoperative Complications / Q000209:etiology*
D001663:Bilirubin