Long-term survival of proximal humerus allografts for reconstruction following resection of malignant bone tumours.
We previously reported early favourable results concerning allograft use in proximal humerus reconstruction following malignancy. We now present the long-term follow-up of patients who underwent tumour resection with massive humeral allograft reconstruction. This is a retrospective review of 8 consecutive patients who underwent massive proximal humeral allograft for primary or secondary bone tumours. The median age at first surgery was 41 years; the median followup is 11.1 years. The overall revision rate of the allografts was 75%. A total of 10 revision procedures were required in this cohort. Five-year survival for implants was 44%; at ten years no implants were intact. Five-year survival for patients was 88%; it was 60% at ten years. In our experience, proximal humerus allograft reconstruction was associated with a high complication rate and resulted in multiple revision procedures in the long-term. We no longer perform or recommend this procedure.
University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Leicester, UK.
Gareth
G
Squire
Tom J
TJ
Grundy
Nicholas A
NA
Ferran
William M
WM
Harper
Robert U
RU
Ashford
D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006811:Humerus / Q000637:transplantation*; D023821:Limb Salvage; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures; D012086:Reoperation / Q000706:statistics & numerical data; D012509:Sarcoma / Q000556:secondary / Q000601:surgery*; D014184:Transplantation, Homologous; D055815:Young Adult