Disseminated microsporidiosis in a renal transplant recipient: case report and review of the literature.
Microsporidia are opportunistic pathogens that usually cause a limited disease in the gastrointestinal tract. Occasionally, they can cause disseminated disease. In solid organ transplant recipients, disseminated disease has been reported only rarely. We describe a 68-year-old woman who presented with fever, cough, and acute kidney injury 6 months after kidney transplantation. Dissemination was confirmed by identification of microsporidial spores in urine and bronchoalveolar lavage fluid. Polymerase chain reaction analysis identified the species as Encephalitozoon cuniculi.
Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.
A
A
Nagpal
B S
BS
Pritt
E C
EC
Lorenz
H
H
Amer
S H
SH
Nasr
L D
LD
Cornell
S
S
Iqbal
M P
MP
Wilhelm
D000368:Aged; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D009670:Encephalitozoon cuniculi / Q000235:genetics / Q000302:isolation & purification*; D016890:Encephalitozoonosis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007668:Kidney / Q000473:pathology; D016030:Kidney Transplantation / Q000009:adverse effects*; D009894:Opportunistic Infections; D013172:Spores, Fungal; D016896:Treatment Outcome
Encephalitozoon; FUO; immunocompromised host; kidney transplant; microsporidiosis