Hypothalamic hamartoma associated with central precocious puberty and growth hormone deficiency.
Hypothalamic hamartomas (HHs) are tumors generally associated with isolated central precocious puberty (CPP). To our knowledge, we report a unique case of a girl with HH associated with CPP and growth hormone deficiency. This case highlights the complex interaction between HHs and the hypothalamic-pituitary-gonadal axis. It also emphasizes the value of close follow-up of growth velocity in these patients even after treatment of the CPP.
Isabelle
I
Rousseau-Nepton
Sagi
S
Kaduri
Natasha
N
Garfield
Preetha
P
Krishnamoorthy
D000293:Adolescent; D005260:Female; D013006:Growth Hormone / Q000172:deficiency*; D006222:Hamartoma / Q000150:complications*; D006801:Humans; D007027:Hypothalamic Diseases / Q000150:complications*; D011629:Puberty, Precocious / Q000209:etiology*
D013006:Growth Hormone