New natural compounds from Rhododendron lepidotum.
Phytochemical investigation of the aerial parts of Rhododendron lepidotum yielded 8-[2',6'-dimethoxy-4'-(1″,2″,3″-trihydroxy-propyl)-phenyl]-7-hydroxy benzopyranone (1), 3-O-β-d-glycopyranosyl betulinic amide (2) and 8-hydroxy-7,7'-oxydicoumarin (4) and five known compounds. Among the known molecules, betulinic amide (3) was earlier reported as a semi-synthetic product. The structures of new molecules 1, 2 and 4 were elucidated on the basis of extensive spectroscopic investigations (1D NMR, 2D NMR and mass spectrometry).
a Natural Product Chemistry Division, Indian Institute of Integrative Medicine (CSIR) , Srinagar , 190 005 , India.
Shakeel-U-Rehman
Shahnawaz Nabi
SN
Sofi
Mohammad Akbar
MA
Khuroo
Subhash Chandra
SC
Taneja
Khursheed Ahmad
KA
Bhat
Ram
R
Vishwakarma
D007294:Inositol / Q000031:analogs & derivatives / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000737:chemistry; D029793:Rhododendron / Q000737:chemistry*; D000094062:Betulinic Acid
D007294:Inositol; D009828:Oleanolic Acid; C508784:(3-oxo-20(29)-lupene-28-oyl)-3-aminopropionamide; D000094062:Betulinic Acid; C021730:pinitol