Non-effect of an antibiotic treatment on dietary fiber-induced goblet cell proliferation in the ileum of rats.
We examined the effect or not of an antibiotic treatment on dietary fiber-induced goblet cell proliferation in the rat ileum. The number of goblet cells in the ileum increased when rats consumed dietary fiber. However, this effect was maintained with a concurrent treatment of antibiotics, suggesting that the fiber effect on goblet cell response would remain irrespective of a bacterial component such as endotoxin.
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University.
Shingo
S
Hino
Hiroyoshi
H
Saita
Tatsuya
T
Morita
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D049109:Cell Proliferation / Q000187:drug effects*; D004043:Dietary Fiber / Q000008:administration & dosage; D004731:Endotoxins / Q000378:metabolism; D020397:Goblet Cells / Q000187:drug effects* / Q000378:metabolism; D007082:Ileum / Q000187:drug effects; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism; D051381:Rats
D000900:Anti-Bacterial Agents; D004043:Dietary Fiber; D004731:Endotoxins