title: The relationship between serum levels of vitamin D and migraine.
abstract: BACKGROUND
  Migraine is common worldwide. In recent years, vitamin D deficiency has been determined as a global health problem. A few studies have shown inverse relationship between serum vitamin D levels and headache. Thus, in this study, we assessed relationship between serum vitamin D levels with migraine.
  
  
  METHODS
  The present study was a cross-sectional. Seventy-six migraine patients aged 10-61 years were included. The multiple linear regression was used to show association between serum 25-0H-D3 and migraine. Adjustments were performed for age, sex, waist circumference, body mass index (BMI), number of chronic diseases, and education level.
  
  
  RESULTS
  The positive weak relationship was observed between serum vitamin D and headache diary result (P = 0.042, r = 0.19). But, no significant relationship was observed between serum vitamin D and migraine severity (P = 0.741).
  
  
  CONCLUSIONS
  High levels of serum 25-OH-D3 was related to higher headache diary result. After adjustment for confounding variables, this significant association remained. No significant relationship was shown between serum vitamin D and migraine severity.
authors: Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Tayebeh
authors: T
authors: Mottaghi
authors: Fariborz
authors: F
authors: Khorvash
authors: Gholamreza
authors: G
authors: Askari
authors: Mohammad Reza
authors: MR
authors: Maracy
authors: Reza
authors: R
authors: Ghiasvand
authors: Zahra
authors: Z
authors: Maghsoudi
authors: Bijan
authors: B
authors: Iraj
keywords: Migraine; relationship; vitamin D
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