title: Tentative biosynthetic pathways of some microbial diketopiperazines.
abstract: Cyclodipeptides and their derivatives, the diketopiperazines (DKPs), constitute a large class of natural products that exhibit various biological properties. Until recently, there are a few characterized DKP biosynthetic pathways. In all these cases, the formation of the cyclodipeptides that harbor the DKP scaffold is catalyzed either by nonribosomal peptide synthetases or by cyclodipeptide synthases. This review focuses on the DKP biosynthetic pathways and their associated molecular mechanisms.
authors: Key Laboratory of Applied Marine Biotechnology of the Ministry of Education, Ningbo University, Ningbo, 315211, China.
authors: Binbin
authors: B
authors: Gu
authors: Shan
authors: S
authors: He
authors: Xiaojun
authors: X
authors: Yan
authors: Lixin
authors: L
authors: Zhang
mesh_terms: D000900:Anti-Bacterial Agents / Q000378:metabolism*; D053898:Biosynthetic Pathways; D054659:Diketopiperazines / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D054659:Diketopiperazines