title: A squaraine and Hg(2+)-based colorimetric and "turn on" fluorescent probe for cysteine.
abstract: A novel squaraine derivative (SQ-1) was synthesized and characterized for the determination of cysteine. Binding with Hg(2+) as a fluorescent quencher to SQ-1 leads to absorption and emission turn-off. More significantly, the SQ-1-Hg(2+) complex exhibits a dual-channel chromofluorogenic responses to biologically important cysteine with a high sensitivity and selectivity over other natural amino acids, along with a low detection limit of 36.7 nM.
authors: Key Laboratory of Analysis and Detection for Food Safety, Ministry of Education, and Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, PR China.
authors: Qian
authors: Q
authors: Lin
authors: Yangwei
authors: Y
authors: Huang
authors: Juan
authors: J
authors: Fan
authors: Ruyong
authors: R
authors: Wang
authors: Nanyan
authors: N
authors: Fu
mesh_terms: D015374:Biosensing Techniques; D003124:Colorimetry; D003503:Cyclobutanes / Q000737:chemistry*; D003545:Cysteine / Q000032:analysis* / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D008628:Mercury / Q000032:analysis / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*
chemical_list: D003503:Cyclobutanes; D005456:Fluorescent Dyes; D010636:Phenols; C480596:squaraine; D008628:Mercury; D003545:Cysteine
keywords: Cysteine; Fluorescent chemosensor; Mercury; Squaraine