title: Drug-induced supersensitivity psychosis revisited: characteristics of relapse in treatment-compliant patients.
abstract: BACKGROUND
  An association between abnormal involuntary movements and psychotic relapse was previously reported in a group of patients compliant with antipsychotic medication (Fallon and Dursun 2011). This was interpreted as the presence of an antipsychotic medication-induced supersensitivity psychosis.
  
  
  METHODS
  From the results of that study and the Chouinard diagnostic criteria for supersensitivity psychosis an abbreviated diagnostic checklist was developed to identify the phenomenon. In the present study the checklist was used on a larger sample of medication-compliant individuals experiencing a psychotic relapse.
  
  
  RESULTS
  The checklist demonstrated its utility by identifying a cause of relapse in 70% (29/41) of patients. Furthermore, it identified the presence of supersensitivity psychosis in 39% (16/41) of patients. This study also replicated a number of findings from the previous paper supporting the idea that supersensitivity psychosis is one cause of relapse in psychosis.
  
  
  CONCLUSIONS
  These results suggested that clinicians should exercise caution in prescribing and may have to augment treatment with other agents or switch to low dopamine-affinity antipsychotics.
authors: Paul
authors: P
authors: Fallon
authors: Serdar
authors: S
authors: Dursun
authors: Bill
authors: B
authors: Deakin
keywords: diagnostic checklist; relapse; supersensitivity psychosis
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