title: Conjunctival malignant melanoma: A rare variant and review of important diagnostic and therapeutic considerations.
abstract: Malignant melanoma of the conjunctiva is a relatively infrequent neoplasm that can be associated with significant morbidity and cause diagnostic difficulty to both the ophthalmologist and pathologist. We herein describe the first reported case in North American and European databases of a rare variant-signet ring cell melanoma - arising in the background of primary acquired melanosis (PAM) and use this case as a review of important diagnostic and therapeutic considerations when faced with this condition.
authors: University of Ottawa Eye Institute, Ottawa, ON, Canada.
authors: Danah H
authors: DH
authors: Albreiki
authors: Steven M
authors: SM
authors: Gilberg
authors: James P
authors: JP
authors: Farmer
keywords: Conjunctival malignant melanoma; Primary acquired melanosis; Signet ring cell
references: Am J Surg Pathol. 1989 Jun;13(6):522-3
references: 2729501
references: Am J Clin Pathol. 1990 Jun;93(6):731-40
references: 2346132
references: Am J Surg Pathol. 1988 Jan;12(1):28-34
references: 2447807
references: Acta Cytol. 1993 Jul-Aug;37(4):559-62
references: 8328253
references: Mod Pathol. 1992 Sep;5(5):515-20
references: 1344815
references: Histopathology. 1991 Jun;18(6):572-5
references: 1879822
references: Br J Ophthalmol. 1992 Mar;76(3):163-5
references: 1540561
references: Am J Surg Pathol. 2008 Mar;32(3):399-406
references: 18300811
references: Ophthalmic Surg Lasers Imaging. 2003 Sep-Oct;34(5):406-8
references: 14509468
references: Oman J Ophthalmol. 2011 May;4(2):97-9
references: 21897630
references: Am J Ophthalmol. 2008 Jan;145(1):124-129
references: 17981257
references: Ophthalmology. 1998 Jan;105(1):191-4
references: 9442798
references: Jpn J Ophthalmol. 2011 Sep;55(5):583-584
references: 21792740
references: Mayo Clin Proc. 1994 Feb;69(2):151-61
references: 8309267
references: J Cutan Pathol. 2011 Jan;38(1):18-24
references: 20860727
references: Br J Ophthalmol. 1996 Jan;80(1):5-8
references: 8664233
references: Insight. 2010 Jan-Mar;35(1):18-21
references: 20218264
references: Am J Ophthalmol. 2001 Jul;132(1):104-6
references: 11438062