title: The interdependence of antibody C and V regions on specificity and affinity: significant implications for the engineering of therapeutic antibodies.
authors: Joshua D
authors: JD
authors: Nosanchuk
mesh_terms: D000818:Animals; D000906:Antibodies / Q000737:chemistry / Q000235:genetics* / Q000276:immunology / Q000627:therapeutic use; D000918:Antibody Specificity; D004358:Drug Therapy; D006801:Humans; D007127:Immunoglobulin Constant Regions / Q000235:genetics* / Q000276:immunology / Q000627:therapeutic use; D007135:Immunoglobulin Variable Region / Q000235:genetics* / Q000276:immunology / Q000627:therapeutic use; D051379:Mice; D015202:Protein Engineering
chemical_list: D000906:Antibodies; D007127:Immunoglobulin Constant Regions; D007135:Immunoglobulin Variable Region
keywords: Bacillus anthracis; C region; V region; antibody; isotope; therapeutics
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