title: When knowing what to do is not sufficient to make good decisions: deficient use of explicit understanding in remitted patients with histories of suicidal acts.
abstract: Disadvantageous decision-making has been reported in patients who had attempted suicide and may represent a cognitive risk factor for suicide. Making decisions necessitates both implicit/associative and explicit/analytic processes. Here, we explored explicit mechanisms, and hypothesized that suicide attempters fail to use explicit understanding to make favorable choices. The Iowa Gambling Task (IGT) was used to assess decision-making in 151 non-depressed patients with a history of mood disorder and suicidal act, 81 non-depressed patients with a history of mood disorders but no suicidal act, and 144 healthy individuals. After performing the task, we assessed the explicit understanding of the participants of the contingencies in the task, i.e. which options yielded higher gain or loss. Correct explicit understanding was reported less often in suicide attempters and affective controls than in healthy controls (45.7% and 42.0% vs. 66.0%). Moreover, understanding was associated with better performance in healthy and affective controls, but not in suicide attempters, with no between-group difference among those who did not reach understanding. Patients with histories of suicide attempt, therefore, show a disconnection between what they "know" and what they "do", possibly reflecting underlying impairments in implicit associative processes. These cognitive alterations should be addressed in preventative interventions targeting suicide.
authors: Department of Psychiatry, McGill University, Montréal, Québec, Canada; Douglas Mental Health University Institute, Montréal, Québec, Canada; McGill Group for Suicide Studies, Montréal, Québec, Canada. Electronic address: fabrice.jollant@mcgill.ca.
authors: Fabrice
authors: F
authors: Jollant
authors: Sébastien
authors: S
authors: Guillaume
authors: Isabelle
authors: I
authors: Jaussent
authors: Antoine
authors: A
authors: Bechara
authors: Philippe
authors: P
authors: Courtet
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002755:Choice Behavior; D003657:Decision Making; D005260:Female; D005715:Gambling / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000175:diagnosis / Q000523:psychology*; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D012959:Socioeconomic Factors; D059020:Suicidal Ideation; D013406:Suicide, Attempted / Q000523:psychology*
keywords: Attempted; Cognition; Comprehension; Decision-making; Mood disorders; Remission; Suicide