title: [Histomorphological analyse of accelerating the fibrocartilage layer repair of patella-patellar tendon junction in rabbits by low intensity pulsed ultrasound stimulation].
abstract: OBJECTIVE
  To analyse the effect of low intensity pulsed ultrasound stimulation (LIPUS) on accelerating the fibrocartilage layer repair of patella-patellar tendon junction.
  
  
  METHODS
  A total of 60 mature female New Zealand white rabbits undergoing standard partial patellectomy were divided into 2 groups randomly. The control group was given comfort treatment and the treatment group was given LIPUS treatment starting from day 3 to the end of week 6 postoperatively. The scheduled time points of animal euthanization would be at week 6, week 12 and week 18 postoperatively. The patella-patellar tendon (PPT) complex would be harvested and cut into sections after decalcification for H&E staining, Safranine o/fast green staining. The thickness and gray value of fibrocartilage layer were analyzed by SANO Microscope Partner image analyzer.
  
  
  RESULTS
  At week 6, week 12 and week 18 postoperatively, the fibrocartilage layer in the treatment group was significantly thicker than that in the control group (P<0.01), and the gray value of fibrocartilage layer was significantly smaller than that in the control group (P<0.01).
  
  
  CONCLUSIONS
  LIPUS helps to accelerate the fibrocartilage layer repair of patella-patellar tendon junction in rabbit models.
authors: Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha 410008; Department of Spinal Surgery, Central Hospital of Yongzhou, Yongzhou Hunan 425000,China.
authors: Baoliang
authors: B
authors: Zhang
authors: Hongbin
authors: H
authors: Lü
authors: Jianzhong
authors: J
authors: Hu
authors: Daqi
authors: D
authors: Xu
authors: Jingyong
authors: J
authors: Zhou
authors: Ye
authors: Y
authors: Wang
mesh_terms: D000818:Animals; D005260:Female; D051445:Fibrocartilage / Q000473:pathology* / Q000503:physiopathology; D010329:Patella / Q000601:surgery; D017847:Patellar Ligament / Q000293:injuries* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D011817:Rabbits; D013708:Tendon Injuries / Q000628:therapy*; D014464:Ultrasonic Therapy / Q000379:methods*; D014945:Wound Healing / Q000502:physiology*