title: All-carbon-nanotube flexible multi-electrode array for neuronal recording and stimulation.
abstract: Neuro-prosthetic devices aim to restore impaired function through artificial stimulation of the nervous system. A lingering technological bottleneck in this field is the realization of soft, micron sized electrodes capable of injecting enough charge to evoke localized neuronal activity without causing neither electrode nor tissue damage. Direct stimulation with micro electrodes will offer the high efficacy needed in applications such as cochlear and retinal implants. Here we present a new flexible neuronal micro electrode device, based entirely on carbon nanotube technology, where both the conducting traces and the stimulating electrodes consist of conducting carbon nanotube films embedded in a polymeric support. The use of carbon nanotubes bestows the electrodes flexibility and excellent electrochemical properties. As opposed to contemporary flexible neuronal electrodes, the technology presented here is both robust and the resulting stimulating electrodes are nearly purely capacitive. Recording and stimulation tests with chick retinas were used to validate the advantageous properties of the electrodes and demonstrate their suitability for high-efficacy neuronal stimulation applications.
authors: School of Electrical Engineering, Tel-Aviv University, Tel-Aviv, 6997801, Israel.
authors: Moshe
authors: M
authors: David-Pur
authors: Lilach
authors: L
authors: Bareket-Keren
authors: Giora
authors: G
authors: Beit-Yaakov
authors: Dorit
authors: D
authors: Raz-Prag
authors: Yael
authors: Y
authors: Hanein
mesh_terms: D000818:Animals; D002645:Chickens; D055664:Electrochemical Techniques; D004566:Electrodes; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009474:Neurons / Q000737:chemistry / Q000166:cytology; D011108:Polymers / Q000737:chemistry*; D012160:Retina / Q000737:chemistry / Q000166:cytology
chemical_list: D037742:Nanotubes, Carbon; D011108:Polymers
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