title: Transitions in latent classes of sexual risk behavior among young injection drug users following HIV prevention intervention.
abstract: We analyzed data from a large randomized HIV/HCV prevention intervention trial with young injection drug users (IDUs). Using categorical latent variable analysis, we identified distinct classes of sexual behavior for men and women. We conducted a latent transition analysis to test the effect of the intervention on transitions from higher to lower risk classes. Men who were in a high-risk class at baseline who received the intervention were 86 % more likely to be in a low-risk class at follow-up compared to those in the control group (p = 0.025). High-risk intervention participants were significantly more likely to transition to the class characterized by unprotected sex with a main partner only, while low-risk intervention participants were significantly less likely to transition to that class. No intervention effect was detected on the sexual risk behavior of women, or of men who at baseline were having unprotected sex with a main partner only.
authors: Division of Epidemiology and Biostatistics, School of Public Health, Community Outreach Intervention Projects , University of Illinois at Chicago, 1603 W. Taylor St., MC 923, Chicago, IL, 60612, USA, mmamiti@uic.edu.
authors: Mary Ellen
authors: ME
authors: Mackesy-Amiti
authors: Lawrence J
authors: LJ
authors: Ouellet
authors: Lorna
authors: L
authors: Finnegan
authors: Holly
authors: H
authors: Hagan
authors: Elizabeth
authors: E
authors: Golub
authors: Mary
authors: M
authors: Latka
authors: Karla
authors: K
authors: Wagner
authors: Richard S
authors: RS
authors: Garfein
mesh_terms: D000293:Adolescent; D000328:Adult; D055030:Drug Users / Q000193:education* / Q000523:psychology / Q000706:statistics & numerical data; D005260:Female; D015658:HIV Infections / Q000517:prevention & control* / Q000523:psychology; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D016485:Needle Sharing / Q000523:psychology / Q000706:statistics & numerical data; D010353:Patient Education as Topic / Q000379:methods*; D010379:Peer Group; D040242:Risk Reduction Behavior; D012309:Risk-Taking; D012725:Sexual Behavior / Q000523:psychology*; D012747:Sexual Partners; D012959:Socioeconomic Factors; D015819:Substance Abuse, Intravenous / Q000523:psychology*; D016896:Treatment Outcome; D047568:Unsafe Sex / Q000517:prevention & control / Q000523:psychology
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