title: One inositol ring to rule thrombosis.
abstract: In this issue of Blood, Ghosh and colleagues report that knocking out an inositol kinase in mice diminishes polyphosphate in platelet dense granules, thereby reducing hemostasis and protecting against thrombosis.
authors: University of Illinois at Urbana-Champaign.
authors: James H
authors: JH
authors: Morrissey
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000378:metabolism*; D008297:Male; D017856:Phosphotransferases (Phosphate Group Acceptor) / Q000502:physiology*; D011122:Polyphosphates / Q000378:metabolism*
chemical_list: D011122:Polyphosphates; D017856:Phosphotransferases (Phosphate Group Acceptor); C099438:inositol hexakisphosphate kinase