title: Bone morphogenetic protein signaling in nephron progenitor cells.
abstract: Bone morphogenetic protein (BMP) signaling plays an essential role in many aspects of kidney development, and is a major determinant of outcome in kidney injury. BMP treatment is also an essential component of protocols for differentiation of nephron progenitors from pluripotent stem cells. This review discusses the role of BMP signaling to nephron progenitor cells in each of these contexts.
authors: Department of Molecular Medicine, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME, 04106, USA, oxburl@mmc.org.
authors: Leif
authors: L
authors: Oxburgh
authors: Aaron C
authors: AC
authors: Brown
authors: Sree Deepthi
authors: SD
authors: Muthukrishnan
authors: Jennifer L
authors: JL
authors: Fetting
mesh_terms: D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000378:metabolism*; D006801:Humans; D009399:Nephrons / Q000196:embryology* / Q000378:metabolism*; D038081:Organogenesis / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*; D013234:Stem Cells / Q000378:metabolism*
chemical_list: D019485:Bone Morphogenetic Proteins
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