title: [Pathological calcifications: a medical diagnosis based on their physicochemical properties].
abstract: This paper gathers different investigations dedicated to pathological calcifications made of apatite in order to define the structural characteristics, which display a clinical significance. Such approach helps the clinician to define the characterisation tools, which have to be combined to obtain such structural characteristics in order to establish a possible relationship between the structural characteristics of the pathological calcifications and the disease. The fact that it is now possible to perform such experiments at the subcellular scale gives new opportunities for a large number of diseases associated to pathological calcification. Moreover, new diagnostic tools based on these characterisation techniques, quite sensitive to analyze microcrystals, can be defined.
authors: CNRS, laboratoire de chimie de la matière condensée de Paris, UPMC, collège de France, 75231 Paris cedex 05, France; Université Paris-XI, laboratoire de physique des solides, 91405 Orsay cedex, France.
authors: Dominique
authors: D
authors: Bazin
authors: AP-HP, hôpital Tenon, service d'explorations fonctionnelles, 75970 Paris cedex 20, France.
authors: Jean-Philippe
authors: JP
authors: Haymann
authors: AP-HP, hôpital Tenon, service d'explorations fonctionnelles, 75970 Paris cedex 20, France.
authors: Emmanuel
authors: E
authors: Letavernier
authors: AP-HP, hôpital Tenon, service d'explorations fonctionnelles, 75970 Paris cedex 20, France.
authors: Julie
authors: J
authors: Rode
authors: AP-HP, hôpital Tenon, service d'explorations fonctionnelles, 75970 Paris cedex 20, France. Electronic address: michel.daudon@tnn.aphp.fr.
authors: Michel
authors: M
authors: Daudon
mesh_terms: D001031:Apatites / Q000737:chemistry*; D002114:Calcinosis / Q000175:diagnosis*; D055598:Chemical Phenomena; D006801:Humans
chemical_list: D001031:Apatites