title: Visualization of adult stem cells within their niches using the Drosophila germline as a model system.
abstract: The germaria of the fruit fly Drosophila melanogaster present an excellent model to study germline stem cell-niche interactions. Two to three adult stem cells are surrounded by a number of somatic cells that form the niche. Here we describe how Drosophilae germaria can be dissected and specifically immuno-stained to allow for identification and analysis of both the adult stem cells and their somatic niche cells.
authors: Max Planck Research Group of Gene Expression and Signaling, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
authors: Annekatrin
authors: A
authors: König
authors: Halyna R
authors: HR
authors: Shcherbata
mesh_terms: D053687:Adult Stem Cells / Q000378:metabolism*; D000822:Animal Husbandry; D000818:Animals; D029721:Drosophila Proteins / Q000378:metabolism; D004331:Drosophila melanogaster / Q000166:cytology*; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D007814:Larva / Q000166:cytology; D008297:Male; D010053:Ovary / Q000166:cytology*; D055153:Stem Cell Niche
chemical_list: D029721:Drosophila Proteins