title: Comparative antimicrobial efficacy of Metapex, Metronidazole, BioPure MTAD, Aztreonam on Bacteroides fragilis and Propionibacterium acne.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the comparative antibacterial efficacy of Biopure MTAD, Metapex, Metronidazole, and Aztreonam against two obligate anerobic bacteria.
  
  
  METHODS
  Antimicrobial efficacy of selected medicaments against two obligate anaerobic bacteria Bacteroides fragilis and Propionibacterium acnes was done by Agar disc-diffusion method. Pre-sterilized Whatman paper discs, 6 mm in diameter and soaked with the test solution, were prepared and placed onto the previously seeded agar Petri plates. Each plate was incubated in anaerobic jar for anerobic environment at 37°C for 48 hours. A zone of inhibition was recorded for each plate and the results were analysed statistically. Saline and ethanol used as control group in this study.
  
  
  RESULTS
  Biopure MTAD, Metapex and Metronidazole were effective against all the selected microorganisms. Aztreonam was effective against Bacteroides fragilis. Saline and ethanol used as control were ineffective.
  
  
  CONCLUSIONS
  Metronidazole showed the superior antibacterial property amongst the tested medicaments.
authors: Department of Conservative Dentistry and Endodontics, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttar Pradesh, India.
authors: Rajkumar
authors: R
authors: Balakrishnan
authors: Sandeep
authors: S
authors: Dubey
authors: Tapan Kumar N
authors: TK
authors: Dhole
authors: Lalit C
authors: LC
authors: Boruah
authors: Sanjeev
authors: S
authors: Srivastava
keywords: Aztreonam; Metapex; Metronidazole; biopure MTAD
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