title: Acute adverse events associated with ventral slot decompression in 546 dogs with cervical intervertebral disc disease.
abstract: OBJECTIVE
  To report the frequency, types, and risk factors for acute perioperative adverse events (AEs) in dogs that had ventral slot decompression (VSD) for cervical intervertebral disc disease (IVDD).
  
  
  METHODS
  Retrospective, case-control study.
  
  
  METHODS
  Dogs (n = 546) with cervical IVDD treated by VSD; 54 cases experiencing AE and 492 controls.
  
  
  METHODS
  Historical, clinical, diagnostic, operative, and outcome data were collected. AE were graded using a Spine Adverse Events Severity (SAVES) system. Associations between the development of AE and hypothesized risk factors were analyzed using bi- and multi-variable analyses.
  
  
  RESULTS
  AE were observed in 54 dogs (9.9%). Minor AE (SAVES Grade 1-2) occurred in 3.5% (19 dogs) and major (SAVES Grades 3-5) AE in 6.4% (35 dogs). Deterioration in neurologic status (n = 13), persistent pain (12), and intraoperative hemorrhage (7) were common major AE. NSAID administration, surgeon experience, C7-T1 disc location, and intraoperative hypotension were significantly associated with AE in multivariate analyses. Improvement of AE occurred in 48/54 (88.9%) of cases, although reoperative neurosurgery was required in 48.5% (17/35) of dogs experiencing major AE. Dogs with major AE had significantly longer hospitalization and worse outcomes than dogs with minor AE or controls. No fatal AE occurred, although 0.7% (4/546) of dogs were euthanatized postoperatively.
  
  
  CONCLUSIONS
  AE occurred in 9.9% of dogs that had VSD, and were significantly associated with perioperative hypotension, C7-T1 disc extrusions, surgeon experience, and NSAID usage. Identification of a major postoperative AE is an indication for immediate diagnostic imaging studies, as 50% of dogs experiencing major AE required reoperation.
authors: Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia.
authors: John H
authors: JH
authors: Rossmeisl
authors: Courtney
authors: C
authors: White
authors: Theresa E
authors: TE
authors: Pancotto
authors: Alicia
authors: A
authors: Bays
authors: P Natalia
authors: PN
authors: Henao-Guerrero
mesh_terms: D000818:Animals; D016022:Case-Control Studies; D002574:Cervical Vertebrae / Q000601:surgery; D019299:Decompression, Surgical / Q000009:adverse effects / Q000662:veterinary*; D004283:Dog Diseases / Q000601:surgery*; D004285:Dogs; D005260:Female; D007405:Intervertebral Disc Displacement / Q000601:surgery / Q000662:veterinary*; D008297:Male; D011183:Postoperative Complications / Q000662:veterinary*; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome