title: Diagnosis and treatment of perianal Crohn disease: NASPGHAN clinical report and consensus statement.
abstract: Inflammatory bowel disease is a chronic inflammatory disorder of the gastrointestinal tract that includes both Crohn disease (CD) and ulcerative colitis. Abdominal pain, rectal bleeding, diarrhea, and weight loss characterize both CD and ulcerative colitis. The incidence of IBD in the United States is 70 to 150 cases per 100,000 individuals and, as with other autoimmune diseases, is on the rise. CD can affect any part of the gastrointestinal tract from the mouth to the anus and frequently will include perianal disease. The first description connecting regional enteritis with perianal disease was by Bissell et al in 1934, and since that time perianal disease has become a recognized entity and an important consideration in the diagnosis and treatment of CD. Perianal Crohn disease (PCD) is defined as inflammation at or near the anus, including tags, fissures, fistulae, abscesses, or stenosis. The symptoms of PCD include pain, itching, bleeding, purulent discharge, and incontinence of stool. In this report, we review and discuss the etiology, diagnosis, evaluation, and treatment of PCD.
authors: Department of Pediatrics, University of Colorado School of Medicine, Children's Hospital Colorado, Denver, CO, USA.
authors: Edwin F
authors: EF
authors: de Zoeten
authors: Brad A
authors: BA
authors: Pasternak
authors: Peter
authors: P
authors: Mattei
authors: Robert E
authors: RE
authors: Kramer
authors: Howard A
authors: HA
authors: Kader
mesh_terms: D000038:Abscess / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D001003:Anal Canal / Q000473:pathology*; D001004:Anus Diseases / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D032921:Consensus; D003424:Crohn Disease / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D005242:Fecal Incontinence / Q000209:etiology; D005401:Fissure in Ano / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D005402:Fistula / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006470:Hemorrhage / Q000209:etiology; D007249:Inflammation / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D010146:Pain / Q000209:etiology; D011538:Pruritus Ani / Q000209:etiology; D013492:Suppuration / Q000209:etiology