title: Angiosarcoma associated with a Kasabach-Merritt syndrome: report of two cases treated with paclitaxel.
abstract: Angiosarcomas are rare, aggressive vascular malignancies of endothelial cell differentiation. Kasabach-Merritt syndrome is a rare condition defined by the association of thrombocytopenia and consumption coagulopathy with specific vascular tumors, such as tufted angioma or kaposiform hemangioendothelioma. We report here two cases of angiosarcomas complicated by a Kasabach-Merritt syndrome and their outcome after treatment with paclitaxel.
authors: Department of Medical Oncology, Institut Bergonié, Bordeaux, France.
authors: Thomas
authors: T
authors: Grellety
authors: Antoine
authors: A
authors: Italiano
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D005260:Female; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D059885:Kasabach-Merritt Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D017239:Paclitaxel / Q000627:therapeutic use*; D011379:Prognosis
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel