title: Quality of life assessment by applying EORTC questionnaires to rectal cancer patients after surgery and neoadjuvant and adjuvant treatment.
abstract: BACKGROUND
  Quality of Life (QoL) is a key element in rectal cancer (RC) patients.
  
  
  OBJECTIVE
  this study assesses QoL in a sample of RC patients in their treatment follow-up period, and compares surgery modalities.
  
  
  METHODS
  eighty four locally advanced RC patients who had received surgery and neoadjuvant chemoradiotherapy were included in the study. Of these, 70 had adjuvant chemotherapy. All patients completed the EORTC QLQ-C30 and the QLQ-CR29 once at least one year after completion of their treatment. Low anterior resection (LAR) patients also completed a Functional Evaluation questionnaire.
  
  
  RESULTS
  QoL scores in the EORTC questionnaires for the sample as a whole were high in most dimensions, in line with the general population´s QoL values, although moderate limitations (> 30 points)were observed in urinary frequency, flatulence, impotence and sexual function. The scores for the Functional Evaluation were adequate (mean combined bowel function score of 18.2). LAR patients had a higher stool frequency than those with abdominoperineal resection (APR; p < 0.001). No differences in body image were found amongst LAR and APR patients. LAR patients with a lower anastomosis had higher faecal incontinence (p = 0.02), whereas those with a reservoir had better emotional functioning (p = 0.04) and higher faecal incontinence (p = 0.03).
  
  
  CONCLUSIONS
  QoL scores and functional evaluation indicated patients had adapted to their disease and treatment. The few differences in QoL found between surgery modalities are in line with other recent studies and in contrast with earlier ones that suggested a lower QoL in APR patients.
authors: Juan Ignacio
authors: JI
authors: Arraras
authors: Javier
authors: J
authors: Suárez
authors: Fernando
authors: F
authors: Arias-de-la-Vega
authors: Ruth
authors: R
authors: Vera
authors: Berta
authors: B
authors: Ibáñez
authors: Gemma
authors: G
authors: Asin
authors: Antonio
authors: A
authors: Viudez
authors: Uxue
authors: U
authors: Zarandona
authors: Mikel
authors: M
authors: Rico
authors: Irene
authors: I
authors: Hernández
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D059186:Chemoradiotherapy, Adjuvant; D013505:Digestive System Surgical Procedures; D005242:Fecal Incontinence; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000601:surgery / Q000628:therapy*; D011795:Surveys and Questionnaires