title: Microencapsulation of stem cells to study cellular interactions.
abstract: Microencapsulation is a technique used in both controlled delivery of materials over time as well as preservation of these materials while delivery is occurring. The range of materials able to be encapsulated is variable, from drugs to living cells. The latter is described here. Electrospray microencapsulation applies a high-voltage field, through which a polymeric material is extruded. A gelling bath, comprising a cross-linking material, is used to create a stable hydrogel containing secondary substances intended for delivery. Control of extrusion parameters, such as flow rate and voltage, allows for specification of diameter and pore sizes of the microcapsules.
authors: Biomedical Engineering Program, University of South Carolina, Columbia, SC, USA.
authors: Keith
authors: K
authors: Moore
authors: Adam
authors: A
authors: Vandergriff
authors: Jay D
authors: JD
authors: Potts
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells; D002214:Capsules; D002478:Cells, Cultured; D016503:Drug Delivery Systems / Q000379:methods*; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry; D059630:Mesenchymal Stem Cells / Q000502:physiology*; D051381:Rats
chemical_list: D002214:Capsules; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate