title: Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011.
abstract: To identify unknown human viruses, we analyzed serum and cerebrospinal fluid samples from patients with unexplained paraplegia from Malawi by using viral metagenomics. A novel cyclovirus species was identified and subsequently found in 15% and 10% of serum and cerebrospinal fluid samples, respectively. These data expand our knowledge of cyclovirus diversity and tropism.
authors: ViroClinics BioSciences BV, Rotterdam, The Netherlands. s.smits@erasmusmc.nl
authors: Saskia L
authors: SL
authors: Smits
authors: Ed E
authors: EE
authors: Zijlstra
authors: Jaap J
authors: JJ
authors: van Hellemond
authors: Claudia M E
authors: CM
authors: Schapendonk
authors: Rogier
authors: R
authors: Bodewes
authors: Anita C
authors: AC
authors: Schürch
authors: Bart L
authors: BL
authors: Haagmans
authors: Albert D M E
authors: AD
authors: Osterhaus
mesh_terms: D002555:Cerebrospinal Fluid / Q000821:virology*; D018136:Circoviridae / Q000145:classification / Q000235:genetics*; D018173:Circoviridae Infections / Q000453:epidemiology / Q000821:virology*; D023061:Gene Order; D005814:Genes, Viral; D016679:Genome, Viral; D006801:Humans; D008295:Malawi; D056186:Metagenomics; D008969:Molecular Sequence Data; D010802:Phylogeny; D015995:Prevalence
keywords: Malawi; Paraplegia; cerebrospinal fluid; cyclovirus; random amplification; serum; virus; viruses
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