title: The pharmacological options in the treatment of eating disorders.
abstract: The eating disorders (DCA) are complex systemic diseases with high social impact, which tend to become chronic with significant medical and psychiatric comorbidities. The literature data showed that there is good evidence to suggest the use of SSRIs, particularly at high doses of fluoxetine, in the treatment of BN reducing both the crisis of binge that the phenomena compensates and reducing the episodes of binge in patients with BED in the short term. Also, the topiramate (an AED) showed a good effectiveness in reducing the frequency and magnitude of episodes of binge with body weight reduction, both in the BN that is in the therapy of BED. To date, modest data support the use of low doses of second-generation antipsychotics in an attempt to reduce the creation of polarized weight and body shapes, the obsessive component, and anxiety in patients with AN. Data in the literature on long-term drug treatment of eating disorders are still very modest. It is essential to remember that the pharmacotherapy has, however, a remarkable efficacy in treating psychiatric disorders that occur in comorbidity with eating disorders, such as mood disorders, anxiety, insomnia, and obsessive-compulsive personality disorders and behavior.
authors: Mental Health Unit, District 24, ASL Napoli 1 Centro, Molosiglio, Via Acton, 80145 Napoli, Italy.
authors: W
authors: W
authors: Milano
authors: M
authors: M
authors: De Rosa
authors: L
authors: L
authors: Milano
authors: A
authors: A
authors: Riccio
authors: B
authors: B
authors: Sanseverino
authors: A
authors: A
authors: Capasso
references: Psychiatry (Edgmont). 2009 Nov;6(11):23-8
references: 20049147
references: Expert Opin Pharmacother. 2012 Oct;13(14):2015-26
references: 22946772
references: J Clin Psychiatry. 2007 Mar;68(3):390-8
references: 17388708
references: Expert Opin Pharmacother. 2004 Nov;5(11):2287-92
references: 15500375
references: Eur Eat Disord Rev. 2010 Jan;18(1):10-21
references: 20054875
references: Curr Clin Pharmacol. 2009 Jan;4(1):78-83
references: 19149506
references: Obesity (Silver Spring). 2008 Sep;16(9):2024-38
references: 19186327
references: Arch Gen Psychiatry. 1986 Feb;43(2):177-81
references: 3511877
references: Br J Psychiatry. 1984 Mar;144:288-92
references: 6367876
references: Eat Behav. 2008 Apr;9(2):129-36
references: 18329590
references: JAMA. 2006 Jun 14;295(22):2605-12
references: 16772623
references: Int J Eat Disord. 2005 Dec;38(4):295-300
references: 16231337
references: Cochrane Database Syst Rev. 2001;(4):CD003391
references: 11687198
references: Adv Ther. 2004 Jul-Aug;21(4):232-7
references: 15605617
references: Adv Ther. 2005 May-Jun;22(3):278-83
references: 16236688
references: Rev Recent Clin Trials. 2009 Jan;4(1):63-9
references: 19149764
references: CNS Drugs. 2009;23(2):139-56
references: 19173373
references: Am J Psychiatry. 2008 Oct;165(10):1281-8
references: 18558642
references: Int Clin Psychopharmacol. 2007 Jul;22(4):197-204
references: 17519642
references: Physiol Behav. 2008 Apr 22;94(1):1-7
references: 18155099
references: Adv Ther. 2005 Jan-Feb;22(1):25-31
references: 15943219
references: Obes Res. 2005 Oct;13(10):1701-8
references: 16286517
references: Lancet. 2010 Feb 13;375(9714):583-93
references: 19931176
references: FEBS Lett. 2008 Jan 9;582(1):132-41
references: 18061579
references: Int J Neuropsychopharmacol. 2012 Mar;15(2):209-22
references: 21439105
references: Int J Neuropsychopharmacol. 2012 Mar;15(2):189-207
references: 21414249
references: J Clin Psychiatry. 1988 Jul;49(7):262-6
references: 3134343
references: J Clin Psychiatry. 2003 Nov;64(11):1335-41
references: 14658948
references: J Clin Psychiatry. 2003 Dec;64(12):1449-54
references: 14728106
references: World J Biol Psychiatry. 2011 Sep;12(6):400-43
references: 21961502
references: Biol Psychiatry. 2007 May 1;61(9):1039-48
references: 17258690
references: Physiol Behav. 2007 Sep 10;92(1-2):263-71
references: 17586536
references: Australas Psychiatry. 2005 Mar;13(1):72-5
references: 15777417
references: Biol Psychiatry. 2007 Feb 1;61(3):348-58
references: 16815322
references: Arch Gen Psychiatry. 1992 Feb;49(2):139-47
references: 1550466
references: Int J Eat Disord. 2012 Mar;45(2):281-9
references: 21744377
references: J Affect Disord. 2011 May;130(3):470-7
references: 21109307
references: CNS Drugs. 2001;15(2):119-36
references: 11460890
references: Child Adolesc Psychiatr Clin N Am. 2009 Jan;18(1):175-87
references: 19014865
references: Arch Gen Psychiatry. 2003 Nov;60(11):1109-16
references: 14609886
references: Am J Psychiatry. 2002 Jan;159(1):96-102
references: 11772696