title: Extraction and Characteristics of Anti-obesity Lipase Inhibitor from Phellinus linteus.
abstract: To develop a potent anti-obesity lipase inhibitor from mushroom, the lipase inhibitory activities of various mushroom extracts were determined. Methanol extracts from Phellinus linteus fruiting body exhibited the highest lipase inhibitory activity (72.8%). The inhibitor was maximally extracted by treatment of a P. linteus fruiting body with 80% methanol at 40℃ for 24 hr. After partial purification by systematic solvent extraction, the inhibitor was stable in the range of 40~80℃ and pH 2.0~9.0. In addition to lipase inhibitory activity, the inhibitor showed 59.4% of superoxide dismutase-like activity and 56.3% of acetylcholinesterase inhibitory activity.
authors: Chungnam Agricultural Research and Extension Services, Yesan 340-861, Korea.
authors: Jong-Kug
authors: JK
authors: Lee
authors: Jeong-Hoon
authors: JH
authors: Jang
authors: Jong-Tae
authors: JT
authors: Lee
authors: Jong-Soo
authors: JS
authors: Lee
keywords: Anti-obesity; Lipase inhibitor; Phellinus linteus
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