title: Indirect effect of financial strain on daily cortisol output through daily negative to positive affect index in the Coronary Artery Risk Development in Young Adults Study.
abstract: Daily affect is important to health and has been linked to cortisol. The combination of high negative affect and low positive affect may have a bigger impact on increasing HPA axis activity than either positive or negative affect alone. Financial strain may both dampen positive affect as well as increase negative affect, and thus provides an excellent context for understanding the associations between daily affect and cortisol. Using random effects mixed modeling with maximum likelihood estimation, we examined the relationship between self-reported financial strain and estimated mean daily cortisol level (latent cortisol variable), based on six salivary cortisol assessments throughout the day, and whether this relationship was mediated by greater daily negative to positive affect index measured concurrently in a sample of 776 Coronary Artery Risk Development in Young Adults (CARDIA) Study participants. The analysis revealed that while no total direct effect existed for financial strain on cortisol, there was a significant indirect effect of high negative affect to low positive affect, linking financial strain to elevated cortisol. In this sample, the effects of financial strain on cortisol through either positive affect or negative affect alone were not significant. A combined affect index may be a more sensitive and powerful measure than either negative or positive affect alone, tapping the burden of chronic financial strain, and its effects on biology.
authors: Department of Psychiatry, University of California, San Francisco, United States. Electronic address: eli.puterman@ucsf.edu.
authors: Eli
authors: E
authors: Puterman
authors: Jana
authors: J
authors: Haritatos
authors: Nancy E
authors: NE
authors: Adler
authors: Steve
authors: S
authors: Sidney
authors: Joseph E
authors: JE
authors: Schwartz
authors: Elissa S
authors: ES
authors: Epel
mesh_terms: D000293:Adolescent; D000328:Adult; D000339:Affect / Q000502:physiology*; D015992:Body Mass Index; D003324:Coronary Artery Disease / Q000453:epidemiology* / Q000523:psychology*; D004522:Educational Status; D005006:Ethnicity; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D007182:Income; D008297:Male; D018570:Risk Assessment; D012959:Socioeconomic Factors; D013315:Stress, Psychological / Q000191:economics* / Q000523:psychology*; D055815:Young Adult
chemical_list: D006854:Hydrocortisone
keywords: Cortisol; Financial strain; Negative affect; Positive affect
references: Emotion. 2012 Apr;12(2):256-67
references: 21787072
references: Integr Physiol Behav Sci. 2001 Jul-Sep;36(3):205-19
references: 11777016
references: Psychosom Med. 2006 Jan-Feb;68(1):41-50
references: 16449410
references: Behav Res Methods Instrum Comput. 2004 Nov;36(4):717-31
references: 15641418
references: Menopause. 2011 Mar;18(3):273-8
references: 21037488
references: Psychosom Med. 2005 Mar-Apr;67(2):281-7
references: 15784795
references: Psychophysiology. 2009 Jul;46(4):862-9
references: 19470128
references: Int J Cardiol. 2009 Jun 26;135(2):175-83
references: 18619689
references: Annu Rev Public Health. 2008;29:235-52
references: 18031225
references: Psychol Methods. 2006 Jun;11(2):142-63
references: 16784335
references: Psychoneuroendocrinology. 2010 Nov;35(10):1573-7
references: 20299157
references: Hormones (Athens). 2009 Jan-Mar;8(1):7-22
references: 19269917
references: Behav Res Methods. 2008 Aug;40(3):879-91
references: 18697684
references: Brain Behav Immun. 2012 Feb;26(2):346-52
references: 22119400
references: Soc Sci Med. 2010 Jul;71(2):259-265
references: 20452712
references: Diabetes Care. 2013 Jan;36 Suppl 1:S67-74
references: 23264425
references: J Pers Soc Psychol. 2001 Oct;81(4):684-96
references: 11642354
references: Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):17058-63
references: 17075058
references: Health Psychol. 2011 Jan;30(1):58-66
references: 21299295
references: Psychosom Med. 2006 Sep-Oct;68(5):657-61
references: 17012518
references: J Pers. 2005 Dec;73(6):1511-38
references: 16274444
references: Psychosom Med. 2012 Feb-Mar;74(2):187-92
references: 22286855
references: J Gerontol B Psychol Sci Soc Sci. 2008 Nov;63(6):S369-74
references: 19092046
references: Psychol Sci. 2010 Jul;21(7):984-91
references: 20501521
references: Cogn Emot. 1998 Mar 1;12(2):191-220
references: 21852890
references: Cogn Emot. 2012;26(8):1412-27
references: 22671768
references: Eur Heart J. 2010 Feb;31(4):424-9
references: 19744954
references: Physiol Rev. 2007 Jul;87(3):873-904
references: 17615391