title: Lymphoplasmacytic hypophysitis associated with immunoglobulin G4.
abstract: We present the unusual case of a 33-year-old woman who presented with a 2 year history of amenorrhoea and an expanding sellar lesion. Initial MRI revealed a lesion in the pituitary fossa, thought to be a pituitary adenoma. One year later, the lesion had enlarged by 5mm, with associated enhancement of the dura of the planum sphenoidale and pituitary stalk. Histopathology revealed a lymphocytic and plasma cell inflammatory infiltrate suggestive of lymphoplasmacytic hypophysitis associated with immunoglobulin G4.
authors: Liverpool Hospital, Elizabeth Street, Liverpool, NSW 2170, Australia. Electronic address: petekhong@yahoo.com.
authors: Peter
authors: P
authors: Khong
authors: Liverpool Hospital, Elizabeth Street, Liverpool, NSW 2170, Australia.
authors: Alar
authors: A
authors: Enno
authors: Liverpool Hospital, Elizabeth Street, Liverpool, NSW 2170, Australia.
authors: Balsam
authors: B
authors: Darwish
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000209:etiology; D005260:Female; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology; D007074:Immunoglobulin G / Q000097:blood / Q000378:metabolism*; D007249:Inflammation / Q000150:complications / Q000276:immunology / Q000473:pathology*; D008214:Lymphocytes; D008279:Magnetic Resonance Imaging; D010900:Pituitary Diseases / Q000150:complications / Q000276:immunology / Q000473:pathology*; D010902:Pituitary Gland / Q000473:pathology; D010950:Plasma Cells
chemical_list: D007074:Immunoglobulin G
keywords: Hypophysitis; Lymphoplasmacytic; Pituitary