title: Bacterial persistence: finding the "sweet spot".
abstract: Studies described by Eisele et al. (2013) and Xavier et al. (2013) in this issue of Cell Host & Microbe show that the bacterial pathogens Salmonella and Brucella exploit the increased levels of glucose present in alternatively activated macrophages to sustain chronic infections in experimentally infected mice.
authors: Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27858, USA. roopr@ecu.edu
authors: R Martin
authors: RM
authors: Roop
authors: Clayton C
authors: CC
authors: Caswell
mesh_terms: D000818:Animals; D002003:Brucella abortus / Q000502:physiology*; D005947:Glucose / Q000378:metabolism*; D054884:Host-Pathogen Interactions; D008262:Macrophage Activation; D008264:Macrophages / Q000382:microbiology*; D050296:Microbial Viability; D047494:PPAR delta / Q000378:metabolism*; D047495:PPAR gamma / Q000378:metabolism*; D012486:Salmonella typhimurium / Q000502:physiology*
chemical_list: D047494:PPAR delta; D047495:PPAR gamma; D005947:Glucose