title: Chitin microneedles for an easy-to-use tuberculosis skin test.
abstract: An easy-to-use tuberculosis skin test is developed with chitin microneedles that deliver purified protein derivative at the correct skin depth and result in a positive test in BCG-immunized guinea pigs.
authors: Department of Materials Science and Engineering, University of Washington, Seattle, WA, 98103, USA.
authors: Jungho
authors: J
authors: Jin
authors: Valerie
authors: V
authors: Reese
authors: Rhea
authors: R
authors: Coler
authors: Darrick
authors: D
authors: Carter
authors: Marco
authors: M
authors: Rolandi
mesh_terms: D000818:Animals; D002686:Chitin / Q000737:chemistry*; D004867:Equipment Design; D006168:Guinea Pigs; D009339:Needles; D012867:Skin / Q000378:metabolism; D057968:Transdermal Patch; D014373:Tuberculin / Q000737:chemistry / Q000276:immunology; D014374:Tuberculin Test / Q000295:instrumentation* / Q000379:methods*; D014376:Tuberculosis / Q000175:diagnosis*
chemical_list: D014373:Tuberculin; D002686:Chitin
keywords: Mantoux test; chitin; diagnostics; microneedles; tuberculosis