title: Radical scavenging activity of selected medicinal plants from Limpopo province of South Africa.
abstract: Plants collected from Limpopo province of South Africa were investigated for their antioxidative potential using the DPPH radical scavenging assay. Acetone extracts of Flueggea virosa had the highest antioxidant activity with an IC₅₀ value of 30 µg/ml, closely matching the ascorbic acid with an IC₅₀ value of 25 µg/ml. The lowest antioxidant readings were observed with extracts of Rhynchosia venulosa (root extract) and Ficus ingens (leaf extract). Acetone extract of Bridelia virosa leaves had the highest phenolic content (156 mg GAE/g extract), while the lowest content was recorded for R. venulosa root extract and leaf extract of F. ingens (8.3 and 17.7 mg GAE/g extract, respectively). There was a linear correlation between antioxidant activity and total phenolic content. Extracts with high phenolic content had low IC₅₀ values, while extracts with low phenolic concentrations had high IC₅₀ values.
authors: Department of Biomedical Sciences, Faculty of Science, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa.
authors: A M
authors: AM
authors: Chauke
authors: L J
authors: LJ
authors: Shai
authors: P M
authors: PM
authors: Mphahlele
authors: M A
authors: MA
authors: Mogale
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000378:metabolism; D044002:Bryophyta / Q000737:chemistry*; D007887:Fabaceae / Q000737:chemistry*; D030681:Ficus / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000494:pharmacology; D010636:Phenols / Q000494:pharmacology*; D010851:Picrates / Q000378:metabolism; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves; D018517:Plant Roots; D010946:Plants, Medicinal / Q000737:chemistry*; D013019:South Africa
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D010636:Phenols; D010851:Picrates; D010936:Plant Extracts; C004931:1,1-diphenyl-2-picrylhydrazyl
keywords: DPPH; antioxidant activity; medicinal plants; phenolics
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