title: Polymeric nanoparticles for optical sensing.
abstract: Nanotechnology is a powerful tool for use in diagnostic applications. For these purposes a variety of functional nanoparticles containing fluorescent labels, gold and quantum dots at their cores have been produced, with the aim of enhanced sensitivity and multiplexing capabilities. This work will review progress in the application of polymeric nanoparticles in optical diagnostics, both for in vitro and in vivo detection, together with a discussion of their biodistribution and biocompatibility.
authors: Cranfield Health, Cranfield University, Cranfield, Bedfordshire MK43 0AL, United Kingdom. Electronic address: f.canfarotta@cranfield.ac.uk.
authors: Francesco
authors: F
authors: Canfarotta
authors: Michael J
authors: MJ
authors: Whitcombe
authors: Sergey A
authors: SA
authors: Piletsky
mesh_terms: D000818:Animals; D006801:Humans; D051379:Mice; D050997:Nanomedicine; D053758:Nanoparticles; D061848:Optical Imaging; D011108:Polymers; D014018:Tissue Distribution
chemical_list: D011108:Polymers
keywords: Diagnostic applications; Fluorescence; Multifunctional nanoparticles; Optical detection; Polymeric coatings; Polymeric nanoparticles; Silica