title: Correlation between waist circumference and carotid intima-media thickness in women from Shanghai, China.
abstract: OBJECTIVE
  To evaluate whether waist circumference (WC) ≥85 cm is related to asymptomatic preclinical atherosclerosis in women from Shanghai, China.
  
  
  METHODS
  A total of 2365 females aged ≥20 years recruited from 4 communities underwent physical examination and carotid artery scanning. Their carotid intima-media thickness (C-IMT) was measured.
  
  
  RESULTS
  The C-IMT was significantly higher in overweight or obese women with their BMI ≥25.0 kg/m2(P<0.01) and in those with their WC ≥85 cm than in those with their WC <85 cm (P<0.01). Spearman and partial correlation analysis showed that the C-IMT was significantly correlated with WC which was independent of menopausal status. The C-IMT significantly increased with the increasing WC and reached to a platform in about 85 cm. An increment tendency was found in the subgroup with its WC <85 cm (P<0.01) while no significant tendency was found in the subgroup with its WC≥85 cm (P=0.07).Multiple stepwise regression analysis showed that the WC was an independent risk factor for C-IMT. In logistic regression model, the odd ratio of WC ≥80 cm, ≥80 cm and <85 cm and ≥85 cm for evaluating the risk of C-IMT elevation was 1.632, 1.501, and 1.878, respectively.
  
  
  CONCLUSIONS
  WC is significantly correlated with C-IMT in women from Shanghai, China, and WC≥85 cm may be used in identifying the risk of subclinical carotid atherosclerosis.
authors: Department of Endocrinology and Metabolism, Affiliated Sixth People’s Hospital of Shanghai Jiaotong University; Shanghai Clinical Center for Diabetes; Shanghai Diabetes Institute; Shanghai Key Laboratory of Diabetes Mellitus; Shanghai 200233, China.
authors: Yun
authors: Y
authors: Shen
authors: Lei
authors: L
authors: Zhang
authors: Wen Hong
authors: WH
authors: Zong
authors: Zheng
authors: Z
authors: Wang
authors: Yin
authors: Y
authors: Zhang
authors: Man Jing
authors: MJ
authors: Yang
authors: Xiao Jing
authors: XJ
authors: Ma
authors: Jia An
authors: JA
authors: Zhu
authors: Yu Qian
authors: YQ
authors: Bao
authors: Wei Ping
authors: WP
authors: Jia
mesh_terms: D000328:Adult; D000368:Aged; D002340:Carotid Artery Diseases / Q000453:epidemiology*; D059168:Carotid Intima-Media Thickness; D002681:China / Q000453:epidemiology; D002947:Cities; D005260:Female; D006801:Humans; D008875:Middle Aged; D050177:Overweight / Q000453:epidemiology*; D012307:Risk Factors; D055105:Waist Circumference