title: Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia.
abstract: BACKGROUND
  Event-related potential studies in schizophrenia have demonstrated amplitude reduction of the P3 in oddball tasks. The P3 has been linked to attention and memory brain functions.
  
  
  METHODS
  In 24 schizophrenia patients and 28 control subjects, wavelet transform was used to reveal event-related modulations of the EEG signal during target trials in delta, theta, alpha, beta, and gamma frequency bands.
  
  
  RESULTS
  Patients showed reductions in P3 amplitude accompanied by reduced low frequency delta-theta and increased beta-gamma band EEG activity.
  
  
  CONCLUSIONS
  These results indicate abnormalities in the synchronization and/or efficiency of neural processes involved in memory and attention networks in schizophrenia.
authors: University of North Carolina at Chapel Hill, Department of Psychiatry, Chapel Hill, NC, USA; Tilburg University, Department of Psychology, Tilburg, the Netherlands. Electronic address: franc_donkers@med.unc.edu.
authors: Franc C L
authors: FC
authors: Donkers
authors: Zoë A
authors: ZA
authors: Englander
authors: Paul H E
authors: PH
authors: Tiesinga
authors: Katherine M
authors: KM
authors: Cleary
authors: Hongbin
authors: H
authors: Gu
authors: Aysenil
authors: A
authors: Belger
mesh_terms: D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D058256:Brain Waves / Q000502:physiology*; D004569:Electroencephalography; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000503:physiopathology*; D058067:Wavelet Analysis; D055815:Young Adult
keywords: Delta frequency band; Gamma frequency band; P3; Schizophrenia; Theta frequency band; Time–frequency analysis; Wavelet analysis