title: Synthesis of a hydrindenone in rings C and D of YW3699.
abstract: A hydrindenone in rings C and D of YW3699 was synthesized starting from (-)-isocarvone. The stereochemical requirement in this ring was successfully achieved by Eschenmoser-Claisen rearrangement followed by alkylation and the aldol reaction to afford the desired hydrindenone, which can be used for further elaboration of YW3699.
authors: Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
authors: Reiko
authors: R
authors: Mizutani
authors: Takahiro
authors: T
authors: Morimitsu
authors: Katsuyuki
authors: K
authors: Nakashima
authors: Motoo
authors: M
authors: Tori
mesh_terms: D000081005:Cyclohexane Monoterpenes; D039821:Monoterpenes / Q000737:chemistry*; D054830:Sesterterpenes / Q000138:chemical synthesis*
chemical_list: D000081005:Cyclohexane Monoterpenes; D039821:Monoterpenes; D054830:Sesterterpenes; C583580:YW3699; C006923:carvone