title: Biomarkers in ANCA-associated vasculitis.
abstract: Despite recent advances in the treatment of antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV), relapse remains common and patients often experience a variable clinical course after initial treatment. New biomarkers are needed to aid the management of these complex diseases. Discoveries regarding the pathogenesis of AAV, from the importance both of activated B and T cells and the alternative complement pathway to genomic data, may lay the groundwork for identification of novel biomarkers.
authors: Division of Rheumatology, Hospital for Special Surgery, 535 E. 70th Street, New York, NY 10021, USA. lallyl@hss.edu
authors: Lindsay
authors: L
authors: Lally
authors: Robert F
authors: RF
authors: Spiera
mesh_terms: D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / Q000097:blood* / Q000276:immunology; D001323:Autoantibodies / Q000097:blood; D001402:B-Lymphocytes / Q000276:immunology / Q000378:metabolism; D015415:Biomarkers / Q000097:blood*; D006801:Humans; D013601:T-Lymphocytes / Q000276:immunology / Q000378:metabolism
chemical_list: D001323:Autoantibodies; D015415:Biomarkers
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