title: ECG-gated cardiac MDCT for detection of systolic anterior motion of mitral valve.
abstract: OBJECTIVE
  Evaluating ECG-gated cardiac MDCT detection of systolic anterior motion of the mitral valve, in comparison to trans-thoracic echocardiography as a gold standard.
  
  
  METHODS
  Study group included 83 consecutive patients (57 men; average age 56.1 years) evaluated with both retrospective ECG-gated cardiac MDCT and trans-thoracic echocardiography within an interval of 30 days. ECG-gated cardiac MDCT imaging was performed with retrospective ECG- gating using 64-slice and 128-slice CT scanners with an inherent temporal resolution range of 75-165 ms. MDCT's and trans- thoracic echocardiograms were retrospectively and independently evaluated by experienced radiologist and cardiologist respectively, for presence of systolic anterior motion of the mitral valve.
  
  
  RESULTS
  7 patients (8.4%) were found to have systolic anterior motion by trans-thoracic echocardiography, from which 6 were found to have systolic anterior motion by ECG-gated cardiac MDCT. Of the 76 patients without systolic anterior motion on trans-thoracic echocardiography, all were correctly identified using ECG-gated cardiac MDCT. The sensitivity, specificity, positive and negative predictive values and accuracy of ECG-gated cardiac MDCT in identifying systolic anterior motion of the mitral valve were 85.7% (6/7), 100% (76/76), 100% (6/6), 98.7% (76/77) and 98.8% (82/83), respectively.
  
  
  CONCLUSIONS
  ECG-gated cardiac MDCT is comparable to trans-thoracic echocardiography in detecting systolic anterior motion of the mitral valve.
authors: Department of Radiology, Leonard M. Miller School of Medicine, University of Miami, Florida, USA. eghersin@med.miami.edu
authors: Eduard
authors: E
authors: Ghersin
authors: Ivan
authors: I
authors: Castellon
authors: Jennifer E
authors: JE
authors: Runco Therrien
authors: Tanyanan
authors: T
authors: Tanawuttiwat
authors: Jonathan
authors: J
authors: Lessick
authors: Adam
authors: A
authors: Checkver
authors: Victor
authors: V
authors: Soto
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D009202:Cardiomyopathies / Q000175:diagnosis*; D004452:Echocardiography / Q000295:instrumentation* / Q000379:methods; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000503:physiopathology*; D061330:Multidetector Computed Tomography / Q000295:instrumentation* / Q000379:methods; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D013599:Systole / Q000502:physiology*