title: 3 TESLA MR imaging in adults with focal onset epilepsy.
abstract: OBJECTIVE
  The finding of cerebral epileptogenic lesions in magnetic resonance (MR) has demonstrated to be a relevant prognostic factor for potential surgical candidates. In a series of consecutive adults with focal onset epilepsy, we investigated the yield of 3T MR imaging for detecting epileptogenic cerebral lesions.
  
  
  METHODS
  We prospectively recruited 161 adult patients with a diagnosis of focal epilepsy, all of whom underwent standardized MR imaging study performed with a 3T magnet.
  
  
  RESULTS
  Lesion-related epilepsy was observed in 48% of patients, and 12% of cryptogenic patients showed subtle or non-specific lesions related to the epileptogenic source. The most common findings were focal cortical dysplasia and vascular lesions, followed by mesial temporal sclerosis, tumors, and scars from previous cerebral injuries. Patients older than 72 years were more likely to have vascular epilepsy.
  
  
  CONCLUSIONS
  Diagnostic assessment using a standardized 3T MR imaging protocol for focal-onset epilepsy detects lesions in nearly half the patients. Our results indicate that elders with focal epilepsy should be searched for vascular lesions.
authors: Epilepsy Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Universitat Autonoma de Barcelona, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain. Electronic address: mtoledo@vhebron.net.
authors: Manuel
authors: M
authors: Toledo
authors: Silvana
authors: S
authors: Sarria-Estrada
authors: Manuel
authors: M
authors: Quintana
authors: Cristina
authors: C
authors: Auger
authors: Xavier
authors: X
authors: Salas-Puig
authors: Estevo
authors: E
authors: Santamarina
authors: Carla
authors: C
authors: Vert
authors: Alex
authors: A
authors: Rovira
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000473:pathology; D001931:Brain Mapping; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology; D020785:Central Nervous System Vascular Malformations / Q000150:complications / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000473:pathology; D002560:Cerebrovascular Circulation; D004828:Epilepsies, Partial / Q000209:etiology / Q000473:pathology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012598:Sclerosis; D013113:Spin Labels; D013702:Temporal Lobe / Q000473:pathology; D055815:Young Adult
chemical_list: D013113:Spin Labels
keywords: Arterial spin labeling; Epilepsy; Magnetic resonance; Seizures; Vascular epilepsy