title: The ANNSERS (Antipsychotic Non-Neurological Side Effects Rating Scale): Validation of Sexual Side-Effect Measurement.
abstract: Antipsychotic nonneurological side effects, such as sexual dysfunction, can adversely affect the quality of patients' relationships, their treatment adherence and their quality of life. In the UK CUtLASS (Cost Utility of the Latest Antipsychotics in Severe Schizophrenia) study, nonneurological side effects were assessed using the ANNSERSv1 (Antipsychotic Non-Neurological Side Effects Rating Scale version 1), a new scale to assess the side effects associated with both first- and second-generation antipsychotic drugs. A total of 26 participants also completed the Derogatis Interview for Sexual Functioning (self-report version, DISF-SR). A statistically significant, and specific, correlation was found between scores on the DISF-SR and the sexual side-effect section of the ANNSERS at baseline. The sexual side-effects subscale of the ANNSERS is a valid measure of sexual dysfunction in the treatment of schizophrenia.
authors: Mental Health and Neurodegeneration Research Group, School of Community-based Medicine, University of Manchester, Manchester, UK.
authors: Ahmed
authors: A
authors: Mahmoud
authors: Karen P
authors: KP
authors: Hayhurst
authors: Richard J
authors: RJ
authors: Drake
authors: Shôn W
authors: SW
authors: Lewis
authors: Thomas R E
authors: TR
authors: Barnes
keywords: adverse effects; antipsychotics; assessment; schizophrenia; sexual dysfunction
references: Psychol Med. 1990 Nov;20(4):843-8
references: 1980954
references: Schizophr Bull. 2006 Oct;32(4):715-23
references: 16540702
references: Int J Clin Pract. 2009 Nov;63(11):1578-88
references: 19780867
references: J Sex Marital Ther. 1997 Winter;23(4):291-304
references: 9427208
references: Eur Psychiatry. 2004 Nov;19(7):415-22
references: 15504648
references: J Psychopharmacol. 2008 May;22(3):323-9
references: 18541627
references: Arch Gen Psychiatry. 2006 Oct;63(10):1079-87
references: 17015810
references: Int Clin Psychopharmacol. 2007 Jul;22(4):238-43
references: 17519648
references: J Psychopharmacol. 2008 May;22(3):244-53
references: 18308789