title: [Cardiac resynchronization therapy in patients with permanent atrial fibrillation].
abstract: In our study we compared effect of cardiac resynchronization therapy (CRT) in chronic heart failure (CHF) patients with permanent atrial fibrillation (AF) and patients with sinus rhythm. Special feature of our work was that patients with permanent atrial fibrillation didnt have obligatory ablation of atrio-ventricular node but underwent aggressive rate control to achieve more than 90% of biventricular (BV) complexes. We used 24 hours Holter monitoring because there are data that this method is more accurate than CRT counters.
  
  
  METHODS
  We included 30 patients: 21 patients with sinus rhythm and 9 patients with permanent AF with ejection fraction <35%, II-IV NYHA class and wide QRS (>120 ms). We examined patients before implantation of CRT and after 6 months.
  
  
  RESULTS
  mean NYHA class decreased from III to II. Distance at 6-min walk test increased by 107 m in AF group and by 105 in sinus rhythm group. EF increased by 7% in AF group and by 6% in sinus rhythm group. Mean time of further observation was 2 years (from 10 months to 5 years). There was 1 death (11.1%) in AF group and 3 deaths (15%) in sinus rhythm group (p>0,05).
  
  
  CONCLUSIONS
  CRT is effective in CHF patients with permanent AF and pharmacological rate control if percent of BV pacing is more than 90% on Holter monitoring.
authors: Iu V
authors: IuV
authors: Mareev
authors: V N
authors: VN
authors: Shitov
authors: V G
authors: VG
authors: Kiktev
authors: O V
authors: OV
authors: Sapel'nikov
authors: R S
authors: RS
authors: Latypov
authors: I R
authors: IR
authors: Grishin
authors: T A
authors: TA
authors: Malkina
authors: L Iu
authors: LIu
authors: Nesterenko
authors: Iu A
authors: IuA
authors: Iuricheva
authors: S F
authors: SF
authors: Sokolov
authors: M A
authors: MA
authors: Saidova
authors: R S
authors: RS
authors: Akchurin
authors: S P
authors: SP
authors: Golitsyn
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000503:physiopathology / Q000628:therapy*; D058406:Cardiac Resynchronization Therapy / Q000379:methods*; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome