title: Multidisciplinary approach as the optimum for surgical treatment of retroperitoneal sarcomas in women.
abstract: BACKGROUND
  The study aimed at evaluating surgical treatment results of retroperitoneal sarcomas (RPS) in female patients in terms of urological and oncological-gynecological collaboration.
  
  
  METHODS
  The authors performed a retrospective review of 17 women who underwent resection of a retroperitoneal tumor. The surgical results, complications, and both overall and disease-free survivals were evaluated. The assessment of a positive surgical margin and the size of the tumor were the second objective. The Kaplan-Meyer survival analysis was used for statistical evaluation.
  
  
  RESULTS
  The median follow-up was 60 (26 - 128) months. The mean age was 55.4 (35 - 75) years. The mean size of tumors was 14.8 (6 - 45) cm. Local recurrences were recorded in three patients, while distal metastases were reported in one patient. Two patients died of distal metastases. The overall and cancer-specific survival was 87.5% and disease-free survival was 76.5%.
  
  
  CONCLUSIONS
  Complete resection is the only effective treatment of retroperitoneal sarcomas. Presence of positive surgical margin is connected with a high risk of local recurrence regardless of an adjuvant chemo-and radiotherapy. The size of tumor had no impact on the survival or risk of local recurrence in the study group. The uro-gynecological collaboration was evaluated as well-suited in this part of oncological surgery.
authors: Department of Urology, Medical Faculty of the Charles University and Faculty Hospital, Hradec Kralove, Czech Republic. brodak@fnhk.cz
authors: M
authors: M
authors: Brodak
authors: J
authors: J
authors: Spacek
authors: J
authors: J
authors: Pacovsky
authors: E
authors: E
authors: Krepinska
mesh_terms: D000328:Adult; D000368:Aged; D003299:Cooperative Behavior; D005260:Female; D006801:Humans; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D012509:Sarcoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*