title: Severe inflammation may be caused by hyperferritinemia of pseudo-pseudo Meigs' syndrome in lupus patients: two cases reports and a literature review.
abstract: Pseudo-pseudo Meigs' syndrome or Tjalma syndrome is a rare manifestation of patients with systemic lupus erythematosus defined by the presence of ascites, pleural effusions, and an elevated cancer antigen 125 level. In this case, we described a patient with lupus who presented with sudden impaired renal function and subsequent development of massive ascites with marked high serum ferritin. Hyperferritinemia is one of the abnormal laboratory findings in severe inflammation with ferritin functioning as an inflammatory marker. However, its correlation with lupus activity remains unclear. Therefore, a review of the literature regarding pseudo-pseudo Meigs' syndrome associated with lupus and high ferritin level in this disease was carried out.
authors: Sang Yeob
authors: SY
authors: Lee
authors: Sung Won
authors: SW
authors: Lee
authors: Won Tae
authors: WT
authors: Chung
mesh_terms: D000328:Adult; D001201:Ascites / Q000175:diagnosis; D015415:Biomarkers / Q000097:blood; D018394:CA-125 Antigen / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D005293:Ferritins / Q000097:blood*; D006801:Humans; D007249:Inflammation / Q000473:pathology*; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000276:immunology*; D008539:Meigs Syndrome / Q000175:diagnosis / Q000276:immunology*; D008875:Middle Aged; D019152:Paracentesis; D010996:Pleural Effusion / Q000175:diagnosis; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
chemical_list: D015415:Biomarkers; D018394:CA-125 Antigen; D005293:Ferritins
references: Lupus. 2002;11(6):348-55
references: 12139372
references: J R Soc Med. 1987 Apr;80(4):252-3
references: 3585894
references: Gynecol Oncol. 2005 Apr;97(1):288-91
references: 15790480
references: Lancet. 2005 Nov 5;366(9497):1672
references: 16271650
references: Int J Gynaecol Obstet. 1995 May;49(2):193-4
references: 7649329
references: Obstet Gynecol. 1954 May;3(5):471-86
references: 13154792
references: Clin Exp Dermatol. 2008 May;33(3):363-4
references: 18419611
references: Eur J Obstet Gynecol Reprod Biol. 2000 Oct;92(2):199-204
references: 10996681
references: Lancet. 2006 Feb 18;367(9510):567-8
references: 16488797
references: Arthritis Res Ther. 2012 Aug 07;14(4):R182
references: 22871034
references: Eur J Gynaecol Oncol. 2000;21(4):362-3
references: 11055482
references: Arch Intern Med. 1998 Jun 22;158(12):1378-9
references: 9645834
references: Obstet Gynecol. 2002 May;99(5 Pt 2):917-9
references: 11975958
references: Clin Rheumatol. 2013 Jun;32(6):899-904
references: 23483294
references: Rheumatol Int. 2011 Apr;31(4):521-3
references: 19844717