title: Favorable effect of modest alcohol consumption to fatty liver disease.
abstract: We previously reported that modest alcohol consumption was significantly inversely associated with fatty liver disease. Feng et al pointed out a discrepancy of statistical significance between our current larger scale cohort and a previous cohort. However, the prevalence of non-alcoholic fatty liver disease was higher in non or minimal drinkers than those in light drinkers in both cohorts. They also argue that some potential co-factors such as soft drink consumption and genetic variations should be discussed.
authors: Masahide
authors: M
authors: Hamaguchi
authors: Takao
authors: T
authors: Kojima
mesh_terms: D000428:Alcohol Drinking; D005234:Fatty Liver / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000503:physiopathology*
keywords: Alcohol; Diabetes; Fatty liver disease; Metabolic syndrome; Obesity
references: World J Gastroenterol. 2013 Apr 7;19(13):2129-30
references: 23599638
references: Ann Intern Med. 2005 Nov 15;143(10):722-8
references: 16287793
references: J Gen Intern Med. 2012 Sep;27(9):1120-6
references: 22282311
references: World J Gastroenterol. 2010 Dec 14;16(46):5830-7
references: 21155004
references: J Hepatol. 2012 Feb;56(2):448-54
references: 21756849
references: Am J Gastroenterol. 2009 Sep;104(9):2189-95
references: 19550408
references: World J Gastroenterol. 2010 Jun 7;16(21):2579-88
references: 20518077
references: World J Gastroenterol. 2012 Jan 21;18(3):237-43
references: 22294826
references: Nat Genet. 2008 Dec;40(12):1461-5
references: 18820647
references: World J Gastroenterol. 2012 Jan 14;18(2):156-67
references: 22253522
references: Am J Gastroenterol. 2007 Sep;102(9):1912-9
references: 17509032
references: World J Gastroenterol. 2010 May 28;16(20):2531-6
references: 20503453
references: N Engl J Med. 2010 Mar 25;362(12):1082-9
references: 20335584