title: A systematic review of interventions for children with cerebral palsy: state of the evidence.
abstract: OBJECTIVE
  The aim of this study was to describe systematically the best available intervention evidence for children with cerebral palsy (CP).
  
  
  METHODS
  This study was a systematic review of systematic reviews. The following databases were searched: CINAHL, Cochrane Library, DARE, EMBASE, Google Scholar MEDLINE, OTSeeker, PEDro, PsycBITE, PsycINFO, and speechBITE. Two independent reviewers determined whether studies met the inclusion criteria. These were that (1) the study was a systematic review or the next best available; (2) it was a medical/allied health intervention; and (3) that more than 25% of participants were children with CP. Interventions were coded using the Oxford Levels of Evidence; GRADE; Evidence Alert Traffic Light; and the International Classification of Function, Disability and Health.
  
  
  RESULTS
  Overall, 166 articles met the inclusion criteria (74% systematic reviews) across 64 discrete interventions seeking 131 outcomes. Of the outcomes assessed, 16% (21 out of 131) were graded 'do it' (green go); 58% (76 out of 131) 'probably do it' (yellow measure); 20% (26 out of 131) 'probably do not do it' (yellow measure); and 6% (8 out of 131) 'do not do it' (red stop). Green interventions included anticonvulsants, bimanual training, botulinum toxin, bisphosphonates, casting, constraint-induced movement therapy, context-focused therapy, diazepam, fitness training, goal-directed training, hip surveillance, home programmes, occupational therapy after botulinum toxin, pressure care, and selective dorsal rhizotomy. Most (70%) evidence for intervention was lower level (yellow) while 6% was ineffective (red).
  
  
  CONCLUSIONS
  Evidence supports 15 green light interventions. All yellow light interventions should be accompanied by a sensitive outcome measure to monitor progress and red light interventions should be discontinued since alternatives exist.
authors: Cerebral Palsy Alliance, Sydney, Australia; University of Notre Dame Australia, Sydney, Australia.
authors: Iona
authors: I
authors: Novak
authors: Sarah
authors: S
authors: McIntyre
authors: Catherine
authors: C
authors: Morgan
authors: Lanie
authors: L
authors: Campbell
authors: Leigha
authors: L
authors: Dark
authors: Natalie
authors: N
authors: Morton
authors: Elise
authors: E
authors: Stumbles
authors: Salli-Ann
authors: SA
authors: Wilson
authors: Shona
authors: S
authors: Goldsmith
mesh_terms: D002547:Cerebral Palsy / Q000628:therapy*; D002648:Child; D002986:Clinical Trials as Topic; D016208:Databases, Factual / Q000706:statistics & numerical data; D006801:Humans; D016896:Treatment Outcome