title: Cupration of C2F5H: isolation, structure, and synthetic applications of [K(DMF)2][(t-BuO)Cu(C2F5)]. Highly efficient pentafluoroethylation of unactivated aryl bromides.
abstract: Pentafluoroethane, C2F5H (HFC-125), is smoothly cuprated with preisolated or in situ-generated [K(DMF)][(t-BuO)2Cu] to give [K(DMF)2][(t-BuO)Cu(C2F5)] (1) in nearly quantitative yield. Complex 1 has been isolated, structurally characterized, and demonstrated to be an exceedingly versatile pentafluoroethylating reagent for a variety of substrates, including unactivated aryl bromides.
authors: Institute of Chemical Research of Catalonia (ICIQ), Tarragona 43007, Spain.
authors: Anton
authors: A
authors: Lishchynskyi
authors: Vladimir V
authors: VV
authors: Grushin
mesh_terms: D003300:Copper / Q000737:chemistry*; D005466:Fluorocarbons / Q000737:chemistry*; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D005466:Fluorocarbons; D006842:Hydrocarbons, Brominated; D009942:Organometallic Compounds; C078256:pentafluoroethane; D003300:Copper