title: Combinatorial drug screening identifies synergistic co-targeting of Bruton's tyrosine kinase and the proteasome in mantle cell lymphoma.
authors: Department of Microbiology, Immunology and Cancer Biology, University of Virginia Health System, Charlottesville, VA, USA.
authors: M
authors: M
authors: Axelrod
authors: Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors: Z
authors: Z
authors: Ou
authors: Division of Hematology/Oncology, University of Virginia Health System, Charlottesville, VA USA.
authors: L K
authors: LK
authors: Brett
authors: Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors: L
authors: L
authors: Zhang
authors: Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors: E R
authors: ER
authors: Lopez
authors: Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors: A T
authors: AT
authors: Tamayo
authors: Department of Microbiology, Immunology and Cancer Biology, University of Virginia Health System, Charlottesville, VA, USA.
authors: V
authors: V
authors: Gordon
authors: Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors: R J
authors: RJ
authors: Ford
authors: Division of Hematology/Oncology, University of Virginia Health System, Charlottesville, VA USA.
authors: M E
authors: ME
authors: Williams
authors: Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors: L V
authors: LV
authors: Pham
authors: Department of Microbiology, Immunology and Cancer Biology, University of Virginia Health System, Charlottesville, VA, USA.
authors: M J
authors: MJ
authors: Weber
authors: Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors: M L
authors: ML
authors: Wang
mesh_terms: D000077329:Agammaglobulinaemia Tyrosine Kinase; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor / Q000379:methods; D004357:Drug Synergism; D006801:Humans; D020522:Lymphoma, Mantle-Cell / Q000188:drug therapy / Q000378:metabolism*; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism*; D061988:Proteasome Inhibitors / Q000494:pharmacology*; D047428:Protein Kinase Inhibitors / Q000494:pharmacology*; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D061988:Proteasome Inhibitors; D047428:Protein Kinase Inhibitors; D011505:Protein-Tyrosine Kinases; D000077329:Agammaglobulinaemia Tyrosine Kinase; D046988:Proteasome Endopeptidase Complex
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