title: A novel and other bioactive secondary metabolites from a marine fungus Penicillium oxalicum 0312F1.
abstract: A new compound 2-(4-hydroxybenzoyl) quinazolin-4(3H)-one (1) and four known compounds were isolated from a marine fungus Penicillium oxalicum 0312F1. The structure of the new compound 1 was elucidated based on the spectroscopic analysis. Bioactivity assays showed that 2-(4-hydroxybenzyl) quinazolin-4(3H)-one (2) and methyl 4-hydroxyphenylacetate (5) had potent inhibitory activity against tobacco mosaic virus (TMV), and the new compound 1 had moderate inhibitory activity against TMV and human gastric cancer cell SGC-7901.
authors: a Institute of Biotechnology of Qinghai Academy of Agriculture and Forestry , Xining , 810016 , P.R. China.
authors: Shuo
authors: S
authors: Shen
authors: Wei
authors: W
authors: Li
authors: Jian
authors: J
authors: Wang
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry* / Q000494:pharmacology*; D015394:Molecular Structure; D010407:Penicillium / Q000737:chemistry*; D014027:Tobacco Mosaic Virus / Q000187:drug effects
chemical_list: D000998:Antiviral Agents