title: Central pontine myelinolysis in advanced HIV infection with tuberculosis and multicentric Castleman's disease.
abstract: We present a case of central pontine myelinolysis (CPM) in a patient with advanced HIV infection and miliary tuberculosis. While hospitalized the patient developed an unusual ataxic variant of CPM with full clinical recovery. Follow-up imaging revealed resolution of pontine lesions. To our knowledge, this is the first report of a clinical and radiological recovery from CPM in advanced HIV disease. Our report extends our knowledge of neurological presentations in patients with advanced HIV infection. It highlights the importance of considering CPM in patients with advanced HIV disease presenting with an ataxic syndrome, even in the absence of an electrolyte derangement.
authors: Department of Infectious Diseases and Gastroenterology, Auguste-Viktoria-Klinikum, Rubensstraße 125 12157 Berlin. juri.katchanov@charite.de
authors: J
authors: J
authors: Katchanov
authors: G
authors: G
authors: Branding
authors: H
authors: H
authors: Stocker
mesh_terms: D000328:Adult; D005871:Castleman Disease / Q000150:complications*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D017590:Myelinolysis, Central Pontine / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014376:Tuberculosis / Q000150:complications*
keywords: AIDS; Africa; Europe; HIV; Mycobacterium tuberculosis; TB; central pontine myelinolysis; multicentric Castleman's disease