title: Electrocatalytic O2 reduction reaction by synthetic analogues of cytochrome P450 and myoglobin: in-situ resonance Raman and dynamic electrochemistry investigations.
abstract: Bioinspired electrodes have been constructed by physiabsorption of two air stable iron porphyrin complexes, one bearing an imidazole coordination and the other bearing a thiolate coordination. To control the electron transfer (ET) rate to these O2 reducing electrocatalysts, the complexes were immobilized on edge plane graphite electrode and alkyl thiol self-assembled monolayer (SAM) modified Au electrodes with varying chain lengths of the thiols. Catalyst immobilized SAM modified surfaces were characterized using surface enhanced resonance Raman spectroscopy (SERRS), and their electrocatalytic O2 reduction properties were investigated using rotating ring disc electrochemistry (RRDE). While the imidazole bound complex showed increase in partially reduced oxygen species (PROS) on decreasing ET rate, the thiolate bound complex showed the opposite trend, that is, the value of PROS reduced on decreasing the ET rate. SERRS coupled to rotating disc electrochemistry (SERRS-RDE) technique helps gain insight into the O2 reduction mechanism. The results obtained indicate that while the imidazole bound iron porphyrin complex reduces O2 through an inner sphere mechanism using a high-spin (HS) Fe(II) species, the thiolate ligated complex shows an inner sphere as well as outer sphere mechanism using a HS Fe(II) and low-spin (LS) Fe(II) species, respectively. The PROS formation by a HS Fe(II) species of this thiolate bound complex increases with decreasing ET rates while that of a LS Fe(II) species decreases with decreasing ET rates.
authors: Department of Inorganic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India.
authors: Sudipta
authors: S
authors: Chatterjee
authors: Kushal
authors: K
authors: Sengupta
authors: Subhra
authors: S
authors: Samanta
authors: Pradip Kumar
authors: PK
authors: Das
authors: Abhishek
authors: A
authors: Dey
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D003577:Cytochrome P-450 Enzyme System / Q000737:chemistry*; D055664:Electrochemical Techniques; D005296:Ferrous Compounds / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry; D008665:Metalloporphyrins / Q000737:chemistry*; D008958:Models, Molecular; D009211:Myoglobin / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D013059:Spectrum Analysis, Raman; D013438:Sulfhydryl Compounds / Q000737:chemistry
chemical_list: D005296:Ferrous Compounds; D007093:Imidazoles; D008665:Metalloporphyrins; D009211:Myoglobin; D013438:Sulfhydryl Compounds; C029899:imidazole; D003577:Cytochrome P-450 Enzyme System; D010100:Oxygen