title: Lipomatous ganglioneuroma of the retroperitoneum.
abstract: Lipomatous ganglioneuroma (LG) is a rare variant of ganglioneuroma that is histologically characterized by a mature adipocytic component admixed with a conventional ganglioneuroma. We report the clinicopathological and immunohistochemical features of an LG in a 44-year-old Chinese male; additionally, we review the literature regarding this type of tumor. Magnetic resonance imaging revealed a left paravertebral soft-tissue mass at the T11-L3 levels. Grossly, the encapsulated neoplasm had a white to yellowish cut surface and rubbery consistency. Microscopic evaluation revealed an encapsulated lesion that consisted of areas of ganglioneuroma admixed with areas of mature fat. By immunohistochemistry, the ganglion cells were positive for chromogranin and synaptophysin, whereas the Schwann cells were positive for vimentin, S-100 protein, and glial fibrillary acidic protein (GFAP). This is the second known report of a retroperitoneal LG. The patient was well and without evidence of disease at 2 years' follow-up.
authors: Department of Pathology, Sixth People's Hospital of Jinan City, Zhangqiu, Shandong Province, China. Electronic address: nosixh@hotmail.com.
authors: Qing-Da
authors: QD
authors: Meng
authors: Department of Orthopedics, Sixth People's Hospital of Jinan City, Zhangqiu, Shandong Province, China.
authors: Xiao-Ning
authors: XN
authors: Ma
authors: Department of Orthopedics, Sixth People's Hospital of Jinan City, Zhangqiu, Shandong Province, China.
authors: Hong
authors: H
authors: Wei
authors: Department of Pathology, Sixth People's Hospital of Jinan City, Zhangqiu, Shandong Province, China.
authors: Rong-Hui
authors: RH
authors: Pan
authors: Department of Orthopedics, Sixth People's Hospital of Jinan City, Zhangqiu, Shandong Province, China.
authors: Wei
authors: W
authors: Jiang
authors: Department of Neurosurgery, Sixth People's Hospital of Jinan City, Zhangqiu, Shandong Province, China.
authors: Fang-Shu
authors: FS
authors: Chen
mesh_terms: D017667:Adipocytes / Q000473:pathology*; D000328:Adult; D005729:Ganglioneuroma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012186:Retroperitoneal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery
keywords: ganglioneuroma; lipomatous ganglioneuroma; retroperitoneal tumors