title: [Clinical characteristics of patients and number of stem cells in the myocardium of right atrial appendage in patients with ischemic heart disease].
abstract: In the last years stem cells (SC) have been identified in rodent and human hearts. These cells have ability to multilineage differentiation in vitro and in vivo and improve cardiac function. The development of new methods of isolation SC offers new approaches to cardiac regeneration. However, the question of how individual patient characteristics influence the number of SC remains unclear. In our study we aimed to define the correlation between patient characteristics and SC number. Our findings suggest that clinical characteristics and severity of the disease may affect the yield of SC in heart tissue. Our data contribute to the development of efficient methods for SC isolation for stem cell therapy.
authors: K V
authors: KV
authors: Dergilev
authors: K A
authors: KA
authors: Rubina
authors: V Iu
authors: VIu
authors: Sysoeva
authors: A I
authors: AI
authors: Gmyzina
authors: G V
authors: GV
authors: Sharonov
authors: E I
authors: EI
authors: Ratner
authors: E V
authors: EV
authors: Parfenova
authors: R S
authors: RS
authors: Akchurin
mesh_terms: D020517:Atrial Appendage / Q000166:cytology*; D002454:Cell Differentiation; D017023:Coronary Angiography; D004452:Echocardiography; D015716:Electrocardiography, Ambulatory; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000601:surgery*; D032383:Myocytes, Cardiac / Q000166:cytology / Q000637:transplantation*; D033581:Stem Cell Transplantation / Q000379:methods*; D013234:Stem Cells / Q000166:cytology*; D016896:Treatment Outcome