title: Pd(0)-catalyzed benzylic arylation-oxidation of 4-methylquinazolines via sp3 C-H activation under air conditions.
abstract: An efficient and selective Pd(0)-catalyzed sp(3) C-H bond arylation-oxidation of 4-methylquinazolines is reported. The method enables the introduction of arylketone at the benzylic position of 4-methylquinazolines without the use of an additional directing group, and atmospheric oxygen is used as the sole oxidant.
authors: State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, P. R. China.
authors: Dan
authors: D
authors: Zhao
authors: Min-Xue
authors: MX
authors: Zhu
authors: Yue
authors: Y
authors: Wang
authors: Qi
authors: Q
authors: Shen
authors: Jian-Xin
authors: JX
authors: Li
mesh_terms: D000388:Air; D001554:Benzene / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D011799:Quinazolines / Q000737:chemistry*
chemical_list: C578786:4-methylquinazoline; D011799:Quinazolines; D010165:Palladium; D001554:Benzene; D010100:Oxygen