title: The prevalence of phenotypic subgroups in Greek women with polycystic ovarian syndrome.
abstract: BACKGROUND
  Since 2003, when the American Society for Reproductive Medicine (ASRM) and European Society of Human Reproduction and Embryology (ESHRE) sponsored consensus established criteria for polycystic ovarian syndrome (PCOS) diagnosis, the phenotypic spectrum of the syndrome has been significantly broadened.
  
  
  OBJECTIVE
  This survey makes an effort to distinguish PCOS according to phenotypic expression and to estimate its prevalence in a Greek population.
  
  
  METHODS
  Greek women from 18 to 35 years of age, who visited the outpatient department, claiming either irregular menstruation (oligo- or anovulation, OA) or clinical manifestations of hyperandrogenemia (HA) were recruited. They gave full disease history and underwent clinical examination, including transvaginal ultrasound (TVUS) scan to identify PCO morphology. Blood samples were collected to perform hormonal and metabolic analyses. Acute or chronic disorders were excluded. Finally, 266 PCOS women constituted the study population.
  
  
  CONCLUSIONS
  The full-blown phenotype (HA+OA+PCO) is the predominant phenotype in this Greek population.
authors: Third Department of Obstetrics and Gynecology, University of Athens, Attikon University Hospital, Athens, Greece.
authors: V
authors: V
authors: Vaggopoulos
authors: E
authors: E
authors: Trakakis
authors: P
authors: P
authors: Panagopoulos
authors: G
authors: G
authors: Basios
authors: I
authors: I
authors: Salloum
authors: C
authors: C
authors: Christodoulaki
authors: C
authors: C
authors: Chrelias
mesh_terms: D000293:Adolescent; D000328:Adult; D000728:Androgens / Q000097:blood; D000735:Androstenedione / Q000097:blood; D000858:Anovulation; D015992:Body Mass Index; D005260:Female; D006115:Greece; D006801:Humans; D017588:Hyperandrogenism; D010641:Phenotype; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000145:classification* / Q000000981:diagnostic imaging; D013739:Testosterone / Q000097:blood; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D000728:Androgens; D013739:Testosterone; D000735:Androstenedione