title: Microsporidial keratitis after collagen cross-linking.
abstract: OBJECTIVE
  To report a case of infectious keratitis due to Microsporidium after collagen crosslinking (CXL).
  
  
  METHODS
  A 36-year-old man presented with a 3-day history of pain, redness and diminution of vision in his left eye. The patient had received CXL for keratoconus in the left eye 6 days prior to presentation. Best-corrected visual acuity (BCVA) was 20/25 OD and counting fingers OS. Slit lamp examination of the left eye showed a central epithelial defect measuring and multiple stromal infiltrates.
  
  
  RESULTS
  Gram and Giemsa staining of corneal scrapings showed spores characteristic of Microsporidia. Hourly 0.5% moxifloxacin eye drops, 0.5% moxifloxcain eye ointment nocte and oral albendazole 400 mg twice daily were commenced. Corneal debridement was performed twice during the first week. At the end of 6 weeks BCVA was 20/60 in the left eye.
  
  
  CONCLUSIONS
  Microsporidial infection can be confirmed on microbiological examination. Our case responded well to medical treatment alone.
authors: Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences , New Delhi , India and.
authors: Gautam
authors: Vishal
authors: V
authors: Jhanji
authors: Gita
authors: G
authors: Satpathy
authors: Sudarshan
authors: S
authors: Khokhar
authors: Tushar
authors: T
authors: Agarwal
mesh_terms: D000328:Adult; D003094:Collagen / Q000008:administration & dosage / Q000009:adverse effects*; D003315:Cornea / Q000382:microbiology / Q000473:pathology; D003432:Cross-Linking Reagents / Q000008:administration & dosage / Q000009:adverse effects*; D003937:Diagnosis, Differential; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D007267:Injections; D007634:Keratitis / Q000175:diagnosis / Q000382:microbiology*; D007640:Keratoconus / Q000601:surgery; D008297:Male; D016814:Microsporidia / Q000302:isolation & purification*; D016881:Microsporidiosis / Q000175:diagnosis / Q000382:microbiology*; D019919:Prosthesis Implantation / Q000009:adverse effects; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000382:microbiology*; D014792:Visual Acuity
chemical_list: D003432:Cross-Linking Reagents; D003094:Collagen