title: Metabolic syndrome, inflammation and atherothrombosis.
abstract: Extensive research of the past decades altered our traditional concept about the genesis of atherosclerosis fundamentally. Today, the crucial role of inflammation in the formation and progression of atherosclerotic plaques is indisputable. Patients at high risk for developing cardiovascular disease, owing to poor diet, obesity and low physical activity have been shown to exhibit a particular inflammatory pattern. Therefore, the present review highlights the crosslink between the metabolic syndrome (MetS), adipose tissue, adipokines and selected inflammatory cytokines in the context of atherothrombosis and cardiovascular disease.
authors: Miklos Rohla, 3rd Medical Department, Cardiology and Emergency Medicine, Wilhelminenhospital, Vienna, Austria, Tel. +43/1/491 50 23 01, Fax +43/1/491 50 23 09, E-mail: miklos.rohla@meduniwien.ac.at.
authors: M
authors: M
authors: Rohla
authors: T W
authors: TW
authors: Weiss
mesh_terms: D000818:Animals; D050197:Atherosclerosis / Q000276:immunology*; D016207:Cytokines / Q000276:immunology*; D006801:Humans; D007249:Inflammation / Q000276:immunology*; D024821:Metabolic Syndrome / Q000276:immunology*; D008955:Models, Cardiovascular; D018448:Models, Immunological; D013927:Thrombosis / Q000276:immunology*
chemical_list: D016207:Cytokines
keywords: Metabolic syndrome; atherosclerosis; cardiovascular disease inflammation