title: Pneumosinus dilatans multiplex associated with hormonal imbalance.
abstract: Pneumosinus dilatans describes an abnormal dilation of one or more paranasal sinuses without radiological evidence of localised bone destruction, hyperostosis or mucous membrane thickening. Dilation of mastoid air cells also occurs rarely along with involvement of paranasal sinuses. This rare combination of unknown aetiology was reported in two cases in the literature and termed 'Pneumosinus Dilatans Multiplex' (PSDM). It is usually asymptomatic, and is detected incidentally on plain radiography, CT or MRI. If left untreated, it can further erode the bone leading to complications such as facial asymmetry, neurological disorders and pathological fractures. The aetiology of the condition remains obscure. Various hypotheses proposed are the presence of gas-forming microorganisms, spontaneous drainage of a mucocele, the presence of a one-way valve, dysregulation of hormonal levels leading to a disturbance of osteoblastic and osteoclastic activity. This paper describes a case of PSDM possibly secondary to hormonal disturbance.
authors: Department of Oral and Maxillofacial Surgery, Amrita School of Dentistry, Ernakulam, Kerala, India.
authors: P
authors: P
authors: Ushas
authors: V
authors: V
authors: Ravi
authors: Jaeson Mohanan
authors: JM
authors: Painatt
authors: Preeti P
authors: PP
authors: Nair
mesh_terms: D000293:Adolescent; D004108:Dilatation, Pathologic / Q000150:complications / Q000175:diagnosis; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications / Q000175:diagnosis*; D008297:Male; D061330:Multidetector Computed Tomography; D010014:Osteolysis / Q000150:complications / Q000175:diagnosis*; D010254:Paranasal Sinus Diseases / Q000150:complications / Q000175:diagnosis*; D011862:Radiography, Panoramic; D014808:Vitamin D Deficiency / Q000150:complications / Q000175:diagnosis*
references: J Craniofac Surg. 2000 Sep;11(5):487-90
references: 11314069
references: J Laryngol Otol. 2002 May;116(5):382-5
references: 12081000
references: J Oral Maxillofac Surg. 2008 Nov;66(11):2380-6
references: 18940511
references: Surg Neurol. 1996 Nov;46(5):471-4
references: 8874548
references: Dentomaxillofac Radiol. 2007 Jul;36(5):298-303
references: 17586858
references: J Craniomaxillofac Surg. 2013 Jan;41(1):28-33
references: 22795165
references: Eur Arch Otorhinolaryngol. 2003 Aug;260(7):386-9
references: 12937914
references: Eur J Dermatol. 2010 Mar-Apr;20(2):205-7
references: 20103498
references: Ann Otol Rhinol Laryngol. 1987 Mar-Apr;96(2 Pt 1):210-2
references: 3566062
references: Ann Otolaryngol Chir Cervicofac. 1965 Jul-Aug;82(7):619-21
references: 5851844
references: J Laryngol Otol. 1955 Feb;69(2):108-14
references: 14354342
references: J Laryngol Otol. 2012 Jan;126(1):88-93
references: 22040674
references: J Craniofac Surg. 2011 May;22(3):978-81
references: 21558910