title: Multiple malignant tumors.
abstract: BACKGROUND
  Due to the improvement in diagnosis and therapy for certain malignant tumors, we are now faced with patients who develop in time multiple malignancies.
  
  
  METHODS
  We conducted a retrospective analysis of the patients diagnosed with at least two primary cancers that were admitted and treated in Cluj-Napoca Municipal Hospital. The study followed patients for a period of 7.5 years.
  
  
  RESULTS
  We included in the present study 217 patients (4.33%) with two or more malignant primary tumors from 5003 cases diagnosed with a primary cancer. The most common sites for multiple malignant tumors were related to the breast, colorectum, urinary bladder, prostate and kidneys.
  
  
  CONCLUSIONS
  We should always take into consideration the possibility of synchronous tumors and we have to keep in mind that a successful treatment of cancer might not prevent the onset of another primary mass.
authors: Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. dacianachirila@gmail.com
authors: D N
authors: DN
authors: Chirila
authors: N A
authors: NA
authors: Turdeanu
authors: N A
authors: NA
authors: Constantea
authors: I
authors: I
authors: Coman
authors: T
authors: T
authors: Pop
authors: R A
authors: RA
authors: Popp
authors: O
authors: O
authors: Balacescu
authors: S C
authors: SC
authors: Vesa
authors: C
authors: C
authors: Ciuce
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000453:epidemiology; D015179:Colorectal Neoplasms / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006773:Hospitals, Municipal; D006801:Humans; D015994:Incidence; D007680:Kidney Neoplasms / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology* / Q000601:surgery; D016609:Neoplasms, Second Primary / Q000453:epidemiology* / Q000601:surgery; D011471:Prostatic Neoplasms / Q000453:epidemiology; D012189:Retrospective Studies; D012383:Romania / Q000453:epidemiology; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology