title: Electroconvulsive therapy and Klinefelter syndrome.
abstract: Klinefelter syndrome is a common sex chromosome disorder characterized by the presence of 1 or more extra X chromosomes, and the most prevalent karyotype is 47,XXY. Epidemiological studies have showed that patients with Klinefelter syndrome had a significantly increased risk of psychosis. We presented a case of a patient with Klinefelter syndrome who was characterized by psychiatric symptoms. The patients had been refractory to clozapine and sodium valproate, but a remarkable improvement occurred after a cycle of 11 sessions of modified electroconvulsive therapy.
authors: Department of Neurology, the First Affiliated Hospital of Anhui Medical University, Anhui Province, China.
authors: Qiang
authors: Q
authors: Wei
authors: Xinhui
authors: X
authors: Xie
authors: Yang
authors: Y
authors: Chen
authors: Yanghua
authors: Y
authors: Tian
authors: Honghao
authors: H
authors: Wang
authors: Keyong
authors: K
authors: Wang
authors: Kai
authors: K
authors: Wang
mesh_terms: D000758:Anesthesia; D004565:Electroconvulsive Therapy / Q000009:adverse effects / Q000379:methods*; D004569:Electroencephalography; D006801:Humans; D007713:Klinefelter Syndrome / Q000150:complications* / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000628:therapy; D012565:Schizophrenic Psychology; D016896:Treatment Outcome