title: A one-pot coupling-addition-cyclocondensation sequence (CACS) to 2-substituted 3-acylpyrroles initiated by a copper-free alkynylation.
abstract: A novel three-component synthesis of 2-substituted 3-acylpyrroles can be initiated by a copper-free Pd-catalyzed alkynylation in a one-pot fashion. The reaction sequence proceeds under mild reaction conditions and in moderate to good yields with a broad scope of diversity.
authors: Lehrstuhl für Organische Chemie, Institut für Organische Chemie und Makromolekulare Chemie, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, D-40225, Düsseldorf, Germany. ThomasJJ.Mueller@uni-duesseldorf.de.
authors: Jan
authors: J
authors: Nordmann
authors: Thomas J J
authors: TJ
authors: Müller
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D003500:Cyclization; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D011758:Pyrroles