title: Recurrent lower gastrointestinal bleeding due to primary colonic Kaposi's sarcoma in a patient with AIDS.
abstract: Epidemic Kaposi's sarcoma remains the most common cancer in patients with human immunodeficiency virus and is associated with significant morbidity and mortality in AIDS patients. Primary visceral Kaposi's sarcoma (Kaposi's sarcoma without cutaneous lesions) presenting with lower gastrointestinal bleeding (LGIB) has rarely been reported. Though Kaposi's sarcoma can occur anywhere in gastrointestinal tract, gastrointestinal symptoms are often non-specific such as chronic blood loss anaemia, vomiting, diarrhoea, intestinal obstruction. In these patients, severe gastrointestinal bleeding requiring repeated blood transfusions is extremely rare. Clinicians should be aware of gastrointestinal tract Kaposi's sarcoma since visceral Kaposi's sarcoma can present in the absence of cutaneous involvement. Endoscopy with biopsy is useful in the diagnosis for severe LGIB in patients with AIDS. Furthermore, gastrointestinal Kaposi's sarcoma should be considered in the differential diagnosis of GI bleeding. We report a case of primary colonic KS who presented with recurrent GI bleeding which was eventually diagnosed by sigmoidoscopy and confirmed pathologically.
authors: Department of Internal Medicine, Sound Shore Medical Center, New Rochelle, USA.
authors: Jie
authors: J
authors: Ling
authors: Roger
authors: R
authors: Coron
authors: Prasanta
authors: P
authors: Basak
authors: Stephen
authors: S
authors: Jesmajian
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000473:pathology* / Q000821:virology; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D001706:Biopsy; D017809:Fatal Outcome; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D005770:Gastrointestinal Neoplasms / Q000150:complications / Q000473:pathology* / Q000821:virology; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D012007:Rectum / Q000473:pathology*; D012008:Recurrence; D012514:Sarcoma, Kaposi / Q000150:complications / Q000473:pathology* / Q000821:virology; D012812:Sigmoidoscopy; D014057:Tomography, X-Ray Computed
keywords: AIDS; HIV; KS; Kaposi's sarcoma; Lower gastrointestinal bleeding; proctitis; rectal; sigmoid colon