title: Changing incidence of orthopedic surgery in rheumatic disease: contributing factors.
abstract: Rheumatic diseases are multisystem conditions that predominantly affect the musculoskeletal system, leading to soft tissue and articular damage. Historically, medical therapy was able to slow, but not prevent, erosion and joint destruction, resulting in the frequent need for orthopedic procedures to maintain function and minimize pain. However, the widespread use of disease-modifying anti-rheumatic drugs (DMARDs) and biologic therapy over the last twenty years has resulted in a dramatic decrease in the incidence of musculoskeletal damage and impairment among these patients. This review will discuss changing patterns of orthopedic surgery among patients with rheumatic diseases, focusing on rheumatoid arthritis and systemic lupus erythematosus.
authors: Division of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA, bernsteine@hss.edu
authors: Elana J
authors: EJ
authors: Bernstein
authors: Lisa A
authors: LA
authors: Mandl
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D006801:Humans; D015994:Incidence; D019637:Orthopedic Procedures / Q000706:statistics & numerical data*; D012216:Rheumatic Diseases / Q000188:drug therapy / Q000601:surgery*
chemical_list: D018501:Antirheumatic Agents
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