title: From germinal matrix to cerebellar haemorrhage.
abstract: For many years cerebellar development after preterm birth has been poorly investigated and has been studied without taking germinal matrix-intraventricular haemorrhage into account. Advanced neuroimaging techniques like magnetic resonance imaging, as well as the use of various acoustic windows (mastoid fontanelle, occipital foramen) have allowed for in vivo diagnosis of acquired focal haemorrhagic lesions in the cerebellum of very preterm babies. The vulnerability of the cerebellum also seems to be related to specific gestational ages, i.e., between 23 and 27 weeks, when rapid growth in cerebellar volume occurs and at a much faster rate than mean brain volume increase. In this paper, the contribution of the cerebellum in long-term motor cognitive, learning and behavioural functions, including psychiatric ones, is discussed.
authors: a NICU, Department of Clinical Sciences and Community Health , Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano , Milan , Italy and.
authors: Monica
authors: M
authors: Fumagalli
authors: a NICU, Department of Clinical Sciences and Community Health , Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano , Milan , Italy and.
authors: Laura
authors: L
authors: Bassi
authors: a NICU, Department of Clinical Sciences and Community Health , Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano , Milan , Italy and.
authors: Ida
authors: I
authors: Sirgiovanni
authors: a NICU, Department of Clinical Sciences and Community Health , Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano , Milan , Italy and.
authors: Fabio
authors: F
authors: Mosca
authors: b Neonatal Intensive Care Unit , Istituto Giannina Gaslini , Genova , Italy.
authors: Andrea
authors: A
authors: Sannia
authors: b Neonatal Intensive Care Unit , Istituto Giannina Gaslini , Genova , Italy.
authors: Luca A
authors: LA
authors: Ramenghi
mesh_terms: D001921:Brain / Q000196:embryology* / Q000473:pathology / Q000503:physiopathology; D002531:Cerebellum / Q000098:blood supply* / Q000254:growth & development / Q000503:physiopathology; D002552:Cerebral Ventricles / Q000098:blood supply; D004453:Echoencephalography; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases; D020300:Intracranial Hemorrhages / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D065886:Neurodevelopmental Disorders / Q000209:etiology
keywords: Brain development; ELBW; GMH-IVH; cerebellar haemorrhages; cerebellar lesions; pons development