title: Quadrupole mass filter: design and performance for operation in stability zone 3.
abstract: The predicted performance of a quadrupole mass filter (QMF) operating in Mathieu stability zone 3 is described in detail using computer simulations. The investigation considers the factors that limit the ultimate maximum resolution (Rmax) and percentage transmission (%Tx), which can be obtained for a given QMF for a particular scan line of operation. The performance curve (i.e., the resolution (R) versus number (N) of radio frequency (rf) cycles experienced by the ions in the mass filter) has been modeled for the upper and lower tip of stability zone 3. The saturation behavior of the performance curve observed in practice for zone 3 is explained. Furthermore, new design equations are presented by examining the intersection of the scan line with stability zone 3. Resolution versus transmission characteristics of stability zones 1 and 3 are compared and the dependence of performance for zones 1 and 3 is related to particular instrument operating parameters.
authors: Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool, L69 3GJ, UK.
authors: Sarfaraz U A H
authors: SU
authors: Syed
authors: Thomas J
authors: TJ
authors: Hogan
authors: Mariya J
authors: MJ
authors: Antony Joseph
authors: Simon
authors: S
authors: Maher
authors: Stephen
authors: S
authors: Taylor
references: Mass Spectrom Rev. 2009 Nov-Dec;28(6):937-60
references: 19492304
references: J Am Soc Mass Spectrom. 2011 Aug;22(8):1381-7
references: 21953192
references: J Am Soc Mass Spectrom. 2012 May;23(5):988-95
references: 22328208