title: Is colonoscopic screening necessary for patients with gastric adenoma or cancer?
abstract: BACKGROUND
  Since colorectal adenoma or cancer is commonly associated with gastric adenoma or cancer, early colorectal adenoma detection can affect the survival of gastric adenoma or cancer patients.
  
  
  OBJECTIVE
  The purpose here was to investigate the colorectal adenoma or cancer prevalence and evaluate the necessity for screening colonoscopy in gastric adenoma or cancer patients.
  
  
  METHODS
  From September 2005 through August 2010, 857 patients younger than 70 years who had gastric adenoma or cancer were enrolled. Healthy age- and sex-matched controls were selected from the general screening population. The prevalence and risk of colorectal adenoma or cancer were compared between the participants and the controls.
  
  
  RESULTS
  Data from 416 patients in the gastric neoplasm group (123 with gastric adenoma and 293 with gastric cancer) and 416 healthy control group participants were included in the statistical analysis. The presence of gastric adenoma or cancer was an independent risk factor for colorectal neoplasm (OR = 1.348, 95 % CI = 1.001-1.815). Patients with diffuse type gastric cancer had a lower prevalence of colorectal adenoma or cancer than those with gastric adenoma or intestinal type cancer. In gastric cancer patients younger than 50 years, intestinal type histology was significantly associated with colorectal adenoma or cancer (OR = 3.838, 95 % CI = 1.077-13.677).
  
  
  CONCLUSIONS
  The colorectal adenoma or cancer risk was significantly increased in patients with gastric adenoma or cancer. Therefore, screening colonoscopy should be considered for gastric adenoma or cancer patients including young patients, in the case of intestinal type gastric cancer.
authors: Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, 516 Gojan-dong, Danwon-gu, Ansan, Gyeonggi-do, 425-707, Korea.
authors: Seung Young
authors: SY
authors: Kim
authors: Sung Woo
authors: SW
authors: Jung
authors: Jong Jin
authors: JJ
authors: Hyun
authors: Ja Seol
authors: JS
authors: Koo
authors: Rok Seon
authors: RS
authors: Choung
authors: Hyung Joon
authors: HJ
authors: Yim
authors: Sang Woo
authors: SW
authors: Lee
authors: Jai Hyun
authors: JH
authors: Choi
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000473:pathology; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D003113:Colonoscopy / Q000592:standards*; D015179:Colorectal Neoplasms / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000150:complications* / Q000473:pathology
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