title: Risk factors for squamous cell carcinoma, a study by the National Dermatology Centre of Colombia.
abstract: BACKGROUND
  Nonmelanoma skin cancer is the most common malignancy in white individuals. The risk factors for squamous cell carcinoma, which belongs to the family of nonmelanoma skin cancers, have not been studied in Colombia.
  
  
  OBJECTIVE
  To determine the risk factors for squamous cell carcinoma in patients at a national referral center for skin diseases in Colombia.
  
  
  METHODS
  We conducted a case-control study that evaluated sociodemographic, epidemiological, and clinical factors among 332 individuals. Risk was calculated as odds ratio (ORs) using the multivariate conditional logistic regression analysis method.
  
  
  RESULTS
  The following risk factors were identified: family history of skin cancer (OR, 6.55; 95% CI, 1.4-28.9), living in a rural area after the age of 30 years (OR, 3.13; 95% CI, 1.3-7.2), a lifetime working outdoors (OR, 2.98; 95% CI, 1.5-5.7), smoking more than 10 cigarettes a day (OR, 2.96; 95% CI, 1.3-6.5), actinic conjunctivitis (OR, 2.68; 95% CI, 1.2-5.9), poikiloderma of Civatte (OR, 3.29; 95% CI, 1.7-6.1), numerous facial actinic keratoses (OR, 9.23; 95% CI, 4.9-17.1), and numerous freckles (OR, 3.68; 95% CI, 1.3-10.1).
  
  
  CONCLUSIONS
  We have documented clinical characteristics and personal history factors that should guide the physician in making decisions on the preventive and follow-up measures to be adopted for individuals at risk of squamous cell carcinoma. These findings may help guide policy for controlling the disease using local information.
authors: Centro Dermatológico Federico Lleras Acosta, E.S.E, Bogotá D.C., Colombia. Electronic address: guillermosanchezvanegas@gmail.com.
authors: G
authors: G
authors: Sánchez
authors: J
authors: J
authors: Nova
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001152:Arsenicals / Q000009:adverse effects; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology*; D016022:Case-Control Studies; D003105:Colombia / Q000453:epidemiology; D005148:Facial Dermatoses / Q000453:epidemiology; D005260:Female; D006801:Humans; D055623:Keratosis, Actinic / Q000453:epidemiology; D008297:Male; D008548:Melanosis / Q000453:epidemiology; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology; D009790:Occupations / Q000706:statistics & numerical data; D011481:Protective Clothing / Q000706:statistics & numerical data; D012307:Risk Factors; D012424:Rural Population / Q000706:statistics & numerical data; D012878:Skin Neoplasms / Q000453:epidemiology*; D012907:Smoking / Q000453:epidemiology; D012959:Socioeconomic Factors; D013472:Sunlight / Q000009:adverse effects; D013473:Sunscreening Agents; D011795:Surveys and Questionnaires; D062606:Tertiary Care Centers / Q000706:statistics & numerical data
chemical_list: D001152:Arsenicals; D013473:Sunscreening Agents
keywords: Carcinoma espinocelular; Case-control studies; Colombia; Estudios de casos y controles; Factores de riesgo; Neoplasias cutáneas; Radiación solar; Risk factors; Skin tumors; Solar radiation; Squamous cell carcinoma