title: Sensitivity and responsiveness of the health-related quality of life in stroke patients-40 (HRQOLISP-40) scale.
abstract: OBJECTIVE
  To investigate the sensitivity and responsiveness of the Health-Related Quality of Life in Stroke Patients-40 (HRQOLISP-40) scale in evaluating stroke patients from onset to 12 months.
  
  
  METHODS
  Fifty-five patients with first-incidence stroke were followed-up for 12 months. The HRQOLISP-40 scale was used to assess health-related quality of life (HRQOL) while stroke severity was assessed with the Stroke Levity Scale. Sensitivity to change was assessed by analyzing changes in the HRQOLISP-40 scores between pairs of months with paired samples t-test. Standardized effect size (SES) and standardized response mean (SRM) were used to express responsiveness.
  
  
  RESULTS
  Overall HRQOL and domains in the physical sphere of the HRQOLISP-40 were sensitive to change at different time intervals in the first 12 months post-stroke. Marked responsiveness (SES and SRM >0.7) was demonstrated by the overall scale, and the physical, psycho-emotional and cognitive domains at varying time intervals. For instance, SRM was greater than 0.7 between 1 and 6, 3 and 12, 1 and 9, and 1 and 12 months for both the physical and psycho-emotional domains.
  
  
  CONCLUSIONS
  The HRQOLISP-40 is a sensitive and responsive stroke-specific quality of life measure that can be used to evaluate the outcome of stroke rehabilitation.
  
  
  CONCLUSIONS
  Enhancing the health-related quality of life (HRQOL) of stroke survivors can be regarded as the ultimate goal of stroke rehabilitation. Sensitive and responsive stroke-specific HRQOL measures are required for use in evaluative studies, and clinical trials and practice. The Health-Related Quality of Life in Stroke Patients-40 (HRQOLISP-40) is a sensitive and responsive stroke-specific scale.
authors: Department of Medical Rehabilitation (Physiotherapy), University of Maiduguri , Borno State , Nigeria .
authors: Grace O
authors: GO
authors: Vincent-Onabajo
authors: Mayowa O
authors: MO
authors: Owolabi
authors: Talhatu K
authors: TK
authors: Hamzat
mesh_terms: D000328:Adult; D000368:Aged; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D011446:Prospective Studies; D011788:Quality of Life; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D020521:Stroke / Q000503:physiopathology / Q000523:psychology*; D000071939:Stroke Rehabilitation
keywords: HRQOLISP-40; Health-related quality of life; health-related quality of life in stroke patients-40 scale; responsiveness; sensitivity; stroke