title: Sympathomimetic amines effectively control pain for interstitial cystitis that had not responded to other therapies.
abstract: OBJECTIVE
  To further investigate the efficacy of treatment of interstitial cystitis that had been refractory to standard treatment with sympathomimetic amines.
  
  
  METHODS
  Dextroamphetamine sulfate sustained release capsules up to 30 mg per day were prescribed in women with refractory painful bladder syndrome/interstitial cystitis in six new cases. The patients were carefully evaluated for relief of symptoms.
  
  
  RESULTS
  All six women found marked relief in their painful bladder syndrome in a rather short length of time. The benefit persisted as long as the therapy was maintained. Temporary cessation resulted in prompt return of symptoms, but resumption of sympathomimetic amines again allowed good relief of bladder pain and related symptoms.
  
  
  CONCLUSIONS
  Because of very few side-effects and no drug dependence in the dosage used, sympathomimetic amines should be considered for first-line therapy.
authors: The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology Division of Reproductive Endocrinology & Infertility, Camden, New Jersey, USA. laurie@ccivf.com
authors: J H
authors: JH
authors: Check
authors: G
authors: G
authors: Cohen
authors: R
authors: R
authors: Cohen
authors: J
authors: J
authors: Dipietro
authors: B
authors: B
authors: Steinberg
mesh_terms: D018856:Cystitis, Interstitial / Q000188:drug therapy* / Q000503:physiopathology; D003913:Dextroamphetamine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010146:Pain / Q000188:drug therapy; D013566:Sympathomimetics / Q000627:therapeutic use*
chemical_list: D013566:Sympathomimetics; D003913:Dextroamphetamine