title: Primary nasal tuberculosis during anti-tumour necrosis factor alpha treatment of a patient with rheumatoid arthritis.
abstract: Anti-tumour necrosis factor alpha (anti-TNFα) therapy is increasingly used in several inflammatory disease processes, including rheumatoid arthritis. However it has a significant potential for adverse events, such as reactivation of latent tuberculosis, which is frequently found in disseminated or extrapulmonary forms. We present a rare case of primary nasal tuberculosis within the context of anti-TNFα therapy for rheumatoid arthritis. To our knowledge, this is the first reported case of primary nasal tuberculosis in a patient with rheumatoid arthritis receiving anti-TNFα therapy.
authors: Department of Internal Medicine, Hospital Santo António, Centro Hospitalar do Porto , Portugal.
authors: Sofia
authors: S
authors: Ribeiro
authors: Betânia
authors: B
authors: Ferreira
authors: Raquel
authors: R
authors: Duarte
authors: Isabel
authors: I
authors: Almeida
authors: Carlos
authors: C
authors: Vasconcelos
mesh_terms: D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009668:Nose Diseases / Q000139:chemically induced* / Q000188:drug therapy / Q000382:microbiology*; D014376:Tuberculosis / Q000139:chemically induced* / Q000188:drug therapy; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D018501:Antirheumatic Agents; D000995:Antitubercular Agents; D014409:Tumor Necrosis Factor-alpha