title: Preventive or potential therapeutic value of nutraceuticals against ionizing radiation-induced oxidative stress in exposed subjects and frequent fliers.
abstract: Humans are constantly exposed to ionizing radiation deriving from outer space sources or activities related to medical care. Absorption of ionizing radiation doses over a prolonged period of time can result in oxidative damage and cellular dysfunction inducing several diseases, especially in ageing subjects. In this report, we analyze the effects of ionizing radiation, particularly at low doses, in relation to a variety of human pathologies, including cancer, and cardiovascular and retinal diseases. We discuss scientific data in support of protection strategies by safe antioxidant formulations that can provide preventive or potential therapeutic value in response to long-term diseases that may develop following exposure.
authors: IC-CNR Area della ricerca di Roma, Monterotondo scalo 00015, Italy. giardi@mlib.cnr.it
authors: Maria Teresa
authors: MT
authors: Giardi
authors: Eleftherios
authors: E
authors: Touloupakis
authors: Delfina
authors: D
authors: Bertolotto
authors: Gabriele
authors: G
authors: Mascetti
mesh_terms: D000337:Aerospace Medicine; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use; D003359:Cosmic Radiation / Q000009:adverse effects; D019587:Dietary Supplements; D004781:Environmental Exposure; D006801:Humans; D018384:Oxidative Stress / Q000187:drug effects* / Q000528:radiation effects; D011832:Radiation Injuries / Q000517:prevention & control*; D011837:Radiation-Protective Agents / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000975:Antioxidants; D011837:Radiation-Protective Agents
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