title: [Supraciliary microstent for open-angle glaucoma: clinical results of a prospective multicenter study].
abstract: OBJECTIVE
  The suprachoroidal CyPass micro-stent is designed to be implanted into the supraciliary space to facilitate aqueous outflow along the uveoscleral pathway in patients with open-angle glaucoma (OAG). This study assessed the safety of micro-stent implantation in patients undergoing cataract surgery.
  
  
  METHODS
  In this multicenter study the CyPass microstent was implanted in patients with OAG undergoing cataract surgery. The implantation was performed using a minimally invasive, conjunctiva-sparing, ab interno intervention. Primary endpoints were safety aspects of the implant, secondary endpoints were the reduction of intraocular pressure (IOP) and topical medication.
  
  
  RESULTS
  There were no severe adverse events during or after surgery in any of the patients. In patients with controlled glaucoma (IOP < 21 mmHg) the average IOP remained constant throughout the 24 month follow-up period but mean medication use decreased from 2.0 at baseline to 1.1 postoperative. In patients with IOP of ≥ 21 mmHg the pressure was reduced by 37 % postoperatively and mean medication decreased from 2.2 at baseline to 1.0.
  
  
  CONCLUSIONS
  The safety profile of combined cataract surgery and CyPass microstent implantation is acceptable and patients also showed a decrease in IOP and medication use.
authors: S
authors: S
authors: Grisanti
authors: E
authors: E
authors: Margolina
authors: H
authors: H
authors: Hoeh
authors: M
authors: M
authors: Rau
authors: C
authors: C
authors: Erb
authors: I
authors: I
authors: Kersten-Gomez
authors: H B
authors: HB
authors: Dick
authors: S
authors: S
authors: Grisanti
mesh_terms: D000368:Aged; D019544:Equipment Failure Analysis; D005260:Female; D005858:Germany; D020327:Glaucoma Drainage Implants; D005902:Glaucoma, Open-Angle / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008904:Miniaturization; D019060:Minimally Invasive Surgical Procedures / Q000295:instrumentation* / Q000379:methods; D011474:Prosthesis Design; D016896:Treatment Outcome
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