title: Versatile synthesis of benzothiophenes and benzoselenophenes by rapid assembly of arylzinc reagents, alkynes, and elemental chalcogens.
abstract: Rapidly aSSembled: The combination of cobalt-catalyzed migratory arylzincation and copper-mediated/catalyzed chalcogenative cyclization allows the construction of benzothiophenes and benzoselenophenes from arylzinc reagents, alkynes, and elemental chalcogens. Benzothiophenes and benzoselenophenes diversely functionalized at the benzene ring moiety can be prepared, which are not readily accessible by conventional methods.
authors: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore) http://www3.ntu.edu.sg/home/nyoshikai/yoshikai_group/Home.html.
authors: Bin
authors: B
authors: Wu
authors: Naohiko
authors: N
authors: Yoshikai
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis / Q000737:chemistry*; D018011:Chalcogens / Q000138:chemical synthesis / Q000737:chemistry*; D003500:Cyclization; D009942:Organometallic Compounds / Q000737:chemistry*; D018036:Selenium Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013876:Thiophenes / Q000138:chemical synthesis* / Q000737:chemistry; D015032:Zinc / Q000737:chemistry*
chemical_list: D000480:Alkynes; D018011:Chalcogens; D009942:Organometallic Compounds; D018036:Selenium Compounds; D013876:Thiophenes; C088015:benzothiophene; D015032:Zinc
keywords: copper; heterocycles; multicomponent coupling; selenium; sulfur