title: Risk factors for tube shunt exposure: a matched case-control study.
abstract: Purpose. To evaluate potential risk factors for developing tube shunt exposure in glaucoma patients. Patients and Methods. Forty-one cases from 41 patients that had tube shunt exposure from 1996 to 2005 were identified from the Robert Cizik Eye Clinic and Bascom Palmer Eye Institute. Each case was matched with 2 controls of the same gender and with tube shunts implanted within 6 months of the index case. Conditional logistic regression was used to determine risk factors. Results. The study cohort includes a total of 121 eyes from 121 patients. The mean age was 63.6 ± 19.7 years, ranging from 1 to 96 years. The average time to exposure was 19.29 ± 23.75 months (range 0.36-85.74 months). Risk factors associated with tube exposure were Hispanic ethnicity (P = 0.0115; OR = 3.6; 95% CI, 1.3-9.7), neovascular glaucoma (P = 0.0064; OR = 28.5; 95% CI, 2.6-316.9), previous trabeculectomy (P = 0.0070; OR = 5.3; 95% CI, 1.6-17.7), and combined surgery (P = 0.0381; OR = 3.7; 95% CI, 1.1-12.7). Conclusions. Hispanic ethnicity, neovascular glaucoma, previous trabeculectomy, and combined surgery were identified as potential risk factors for tube shunt exposure. These potential risk factors should be considered when determining the indication for performing tube shunt implantation and the frequency of long-term followup.
authors: Ruiz Department of Ophthalmology and Visual Science, The University of Texas Medical School at Houston, 6431 Fannin Street, MSB 7.024, Houston, TX 77030, USA ; Glaucoma Service, Wills Eye Institute, 840 Walnut Street, Philadelphia, PA 19107, USA.
authors: Michael S
authors: MS
authors: Koval
authors: Fouad F
authors: FF
authors: El Sayyad
authors: Nicholas P
authors: NP
authors: Bell
authors: Alice Z
authors: AZ
authors: Chuang
authors: David A
authors: DA
authors: Lee
authors: Stephen M
authors: SM
authors: Hypes
authors: Davinder S
authors: DS
authors: Grover
authors: Laura A
authors: LA
authors: Baker
authors: Stephen M
authors: SM
authors: Huddleston
authors: Donald L
authors: DL
authors: Budenz
authors: Robert M
authors: RM
authors: Feldman
references: J Glaucoma. 2008 Jan-Feb;17(1):48-51
references: 18303385
references: Ophthalmology. 2011 Mar;118(3):443-52
references: 20932583
references: Ophthalmology. 2007 Dec;114(12):2265-70
references: 17466376
references: Ophthalmology. 2002 Oct;109(10):1916-20
references: 12359614
references: Ophthalmology. 2001 Jul;108(7):1323-7
references: 11425695
references: Am J Ophthalmol. 2012 May;153(5):804-814.e1
references: 22244522
references: Curr Opin Ophthalmol. 2004 Apr;15(2):141-6
references: 15021227
references: J Glaucoma. 2002 Apr;11(2):143-7
references: 11912362
references: Ophthalmology. 2008 Jun;115(6):1089-98
references: 18519069
references: J Glaucoma. 2013 Aug;22(6):433-8
references: 21673598
references: JAMA. 2003 Oct 8;290(14):1884-90
references: 14532317
references: Jpn J Ophthalmol. 2009 Mar;53(2):114-119
references: 19333694
references: Ophthalmology. 2005 Oct;112(10):1801-8
references: 16111757