title: Regioselective hydroxylation and glucosylation of flavanones with cultured plant cells of Eucalyptus perriniana.
abstract: Cultured plant cells of Eucalyptus perriniana catalyzed reduction, regioselective hydroxylation, and regioselective glycosylation of flavanones. (2S)-Flavanone was converted into (2S)-flavan-4-ol, (2S)-flavan-4,7-diol, (2S)-flavan-7-ol, (2S)-flavan-7-yl glucoside, and (2S)-flavan-7-yl gentiobioside. The cells glucosylated (2S)-flavan-6-ol to (2S)-flavan-6-yl glucoside. (2S)-Flavan-2'-ol was transformed to (2S)-flavan-2',4-diol, (2S)-flavan-2',7-diol, (2S)-flavan-2'-yl glucoside. In addition, (2S)-flavan-4'-ol was transformed to (2S)-flavan-4,4'-diol, (2S)-flavan-4',7-diol, (2S)-flavan-4'-yl glucoside.
authors: Department of Pharmacology, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.
authors: Ryusuke
authors: R
authors: Hosoda
authors: Yoshiyuki
authors: Y
authors: Horio
authors: Kei
authors: K
authors: Shimoda
authors: Manabu
authors: M
authors: Hamada
authors: Hatsuyuki
authors: H
authors: Hamada
authors: Hiroki
authors: H
authors: Hamada
mesh_terms: D001711:Biotransformation; D002478:Cells, Cultured; D005052:Eucalyptus / Q000378:metabolism*; D044950:Flavanones / Q000378:metabolism*; D006031:Glycosylation; D006900:Hydroxylation
chemical_list: D044950:Flavanones