title: Ru-catalyzed 1,4-addition of arylboronic acids to acrylic acid derivatives in the presence of phenols.
abstract: [Ru(p-cymene)Cl2]2-catalyzed 1,4-addition reactions between arylboronic acids and butyl acrylate and acrylamide in the presence of phenols were investigated, good to excellent yields were obtained. The addition of phenols remarkably promoted the protonolysis and inhibited the β-H elimination of the 1,4-addition intermediates, and also efficiently suppressed the protonolysis of arylboronic acids.
authors: School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China.
authors: Lei
authors: L
authors: Zhang
authors: Xiaomin
authors: X
authors: Xie
authors: Zhiyong
authors: Z
authors: Peng
authors: Lei
authors: L
authors: Fu
authors: Zhaoguo
authors: Z
authors: Zhang
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D000081007:Cymenes; D039821:Monoterpenes / Q000737:chemistry; D010636:Phenols / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D000179:Acrylates; D001897:Boronic Acids; D000081007:Cymenes; D039821:Monoterpenes; D010636:Phenols; C007210:4-cymene; C032490:n-butyl acrylate; D012428:Ruthenium; C036658:acrylic acid