title: A 22-year-old man with severe osteoporosis due to prolactinoma.
abstract: Prolactin-secreting adenomas represent nearly 40% to 60% of all pituitary adenomas. Prolactin inhibits the secretion of gonadotropin-releasing hormone that is responsible for the synthesis and secretion of gonadotropins. Sex steroids have an important effect on the regulation of bone metabolism in men. Decreased libido and impotence are the most common presenting symptoms of hyperprolactinemia in males. These symptoms are easily neglected by both patients and some physicians. We present a 22-year-old man with multiple osteoporotic fractures associated with prolactinoma despite the use of teriparatide for 18 months. We emphasize and highlight the importance of hyperprolactinemia and fractures caused by high prolactin levels.
authors: Department of Physical Medicine and Rehabilitation, Haydarpaşa Training Hospital, Gülhane Military Medical Academy, İstanbul, Turkey. dandinoglu@gmail.com
authors: Taner
authors: T
authors: Dandinoğlu
authors: Selim
authors: S
authors: Akarsu
authors: Levent
authors: L
authors: Tekin
authors: Serkan
authors: S
authors: Arbal
authors: Umit
authors: U
authors: Dinçer
mesh_terms: D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D019468:Disease Management; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D058866:Osteoporotic Fractures / Q000175:diagnosis / Q000209:etiology; D010911:Pituitary Neoplasms / Q000150:complications* / Q000175:diagnosis*; D011388:Prolactin / Q000378:metabolism; D015175:Prolactinoma / Q000150:complications* / Q000175:diagnosis*; D012720:Severity of Illness Index; D019379:Teriparatide / Q000627:therapeutic use; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D050071:Bone Density Conservation Agents; D019379:Teriparatide; D011388:Prolactin