title: A convenient method to screen for carbapenemase-producing Pseudomonas aeruginosa.
abstract: A combined-disk method using imipenem and cloxacillin was evaluated to discriminate between carbapenemase-producing (n = 56) and nonproducing (n = 62) strains of Pseudomonas aeruginosa. With a cloxacillin load of 4,000 μg/disk, this very simple method showed a sensitivity and a specificity of 100%, irrespective of the type of carbapenemase produced.
authors: Centre National de Référence de la Résistance aux Antibiotiques, Centre Hospitalier Régional Universitaire de Besançon, Besançon, France.
authors: Damien
authors: D
authors: Fournier
authors: Pauline
authors: P
authors: Garnier
authors: Katy
authors: K
authors: Jeannot
authors: Amélie
authors: A
authors: Mille
authors: Anne-Sophie
authors: AS
authors: Gomez
authors: Patrick
authors: P
authors: Plésiat
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000032:analysis*; D001431:Bacteriological Techniques / Q000379:methods*; D003023:Cloxacillin / Q000494:pharmacology; D006801:Humans; D011552:Pseudomonas Infections / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000201:enzymology*; D012680:Sensitivity and Specificity; D001618:beta-Lactamases / Q000032:analysis*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase; D003023:Cloxacillin
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