title: Isotretinoin-induced skin fragility in a teenaged athlete: a case report.
abstract: Isotretinoin is approved by the US Food and Drug Administration for the treatment of severe recalcitrant nodular acne. Mucocutaneous toxicity is the most commonly observed side effect of isotretinoin use. Because atrophy and skin fragility may occur while taking isotretinoin, most warnings recommend avoidance of cosmetic procedures, such as dermabrasion, laser treatments, waxing, and chemical peels. We report a case of isotretinoin-induced skin fragility in a 16-year-old adolescent boy who presented with an unusual amount of skin erosions and excoriations on his face during wrestling season. We propose that it may be prudent to advise athletes who are involved in contact sports that skin fragility and increased erosions may occur during or after their course of treatment with isotretinoin.
authors: 181 N Belle Mead Rd, Ste 5, East Setauket, NY 11733, USA. michelle.pavlis@gmail.com.
authors: Michelle B
authors: MB
authors: Pavlis
authors: Lawrence
authors: L
authors: Lieblich
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy; D000293:Adolescent; D001265:Athletic Injuries / Q000473:pathology; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology; D014952:Wrestling
chemical_list: D003879:Dermatologic Agents; D015474:Isotretinoin