title: Ongoing applicative studies of plant thioredoxins.
abstract: Studies triggered by the discovery of the function of thioredoxin (Trx) in photosynthesis have revealed its role throughout biology. Parallel biochemical and proteomic analyses have led to the identification of its numerous putative targets. Recently, to verify the biological significance of these targets, in vivo studies using transformants in which Trx is overexpressed or suppressed are in progress, and the transformants themselves that are being used in such studies show their potential applicative values. Moreover, Trx's mitigation of allergenicity for some proteins offers promising prospects in the food industry. Practical studies based on redox regulation, once only on the horizon, are now achieving new dimensions. This short review focuses on the industrial applications of Trx studies, the current situation, and future perspectives. The putative targets obtained by the proteomics approach in comparison with in vivo observations of the transformants are also examined. Applicative studies of glutathione, a counterpart of Trx, are also discussed briefly.
authors: National Food Research Institute, National Agriculture and Food Research Organization, Kannondai 2-1-12, Tsukuba, Ibaraki 305-8642, Japan.
authors: Hiroyuki
authors: H
authors: Yano
mesh_terms: D005978:Glutathione / Q000378:metabolism; D007221:Industry; D010944:Plants / Q000378:metabolism; D013879:Thioredoxins / Q000276:immunology / Q000378:metabolism
chemical_list: D013879:Thioredoxins; D005978:Glutathione
keywords: allergen; food; redox regulation; target; thioredoxin.