title: Isolation of new flavan-3-ol and lignan glucoside from Loropetalum chinense and their antimicrobial activities.
abstract: Phytochemical and antimicrobial activity study on the ethanol extract of the leaves and stems of Loropetalum chinense led to the isolation of a new flavan-3-ol compounds, 8-[1-(3,4-dihydroxyphenyl)-3-methoxy-3-oxopropyl]-catechin (loropetaliside A) (1) and a new lignan glucoside, 1-(5-hydroxy-3-methoxyphenyl)-2-(2-β-glucopyranosyl-4-hydroxy-5-(1-(E)propen-3-ol)-phenyl)-propane-3-ol (loropetaliside B) (3) and several known compounds manglieside D (2), quercetin (4), kaempferol-3-O-D-glucopyranoside (5), quercetin-3-O-β-L-rhamnoside (6) and tiliroside (7). Their structures were elucidated on the basis of extensive spectroscopic analysis.
authors: College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang 330045, PR China.
authors: Qinghua
authors: Q
authors: Zhang
authors: Dan
authors: D
authors: Fan
authors: Bingjian
authors: B
authors: Xiong
authors: Lingbao
authors: L
authors: Kong
authors: Xiangdong
authors: X
authors: Zhu
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029201:Hamamelidaceae / Q000737:chemistry*; D044949:Kaempferols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D018515:Plant Leaves; D018547:Plant Stems; D011794:Quercetin / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D005419:Flavonoids; D005960:Glucosides; D044949:Kaempferols; D017705:Lignans; D010936:Plant Extracts; C052083:tiliroside; C006552:kaempferol; D011794:Quercetin
keywords: Antimicrobial activity; Loropetaliside A; Loropetaliside B; Loropetalum chinense