title: The Anti-inflammatory Effects of Water Extract from Cordyceps militaris in Murine Macrophage.
abstract: The aim of this study was to determine the in vitro anti-inflammatory effect of hot water extract from Cordyceps militaris fruiting bodies (CMWE) on lipopolysaccharide (LPS)-stimulated nitric oxide (NO) production, tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) release in RAW 264.7 cells. The treatment of macrophages with various concentrations of hot CMWE significantly reduced LPS-induced production as well as NO, TNF-α and IL-6 secretion in a concentration-dependent manner. These results suggest that CMWE have potent inhibitory effects on the production of these inflammatory mediators.
authors: Department of Microbiology, Dong-A University College of Medicine, Busan 604-714, Korea.
authors: Wol Soon
authors: WS
authors: Jo
authors: Yoo Jin
authors: YJ
authors: Choi
authors: Hyoun Ji
authors: HJ
authors: Kim
authors: Jae Yun
authors: JY
authors: Lee
authors: Byung Hyouk
authors: BH
authors: Nam
authors: Jae Dong
authors: JD
authors: Lee
authors: Sang Wha
authors: SW
authors: Lee
authors: Su Yeong
authors: SY
authors: Seo
authors: Min Ho
authors: MH
authors: Jeong
keywords: Anti-inflammatory activity; Cordyceps militaris; Lipopolysaccharide; Nitric oxide; Pro-inflammatory cytokines; RAW 264.7 cell
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