title: A whole-genome DNA marker map for cotton based on the D-genome sequence of Gossypium raimondii L.
abstract: We constructed a very-high-density, whole-genome marker map (WGMM) for cotton by using 18,597 DNA markers corresponding to 48,958 loci that were aligned to both a consensus genetic map and a reference genome sequence. The WGMM has a density of one locus per 15.6 kb, or an average of 1.3 loci per gene. The WGMM was anchored by the use of colinear markers to a detailed genetic map, providing recombinational information. Mapped markers occurred at relatively greater physical densities in distal chromosomal regions and lower physical densities in the central regions, with all 1 Mb bins having at least nine markers. Hotspots for quantitative trait loci and resistance gene analog clusters were aligned to the map and DNA markers identified for targeting of these regions of high practical importance. Based on the cotton D genome reference sequence, the locations of chromosome structural rearrangements plotted on the map facilitate its translation to other Gossypium genome types. The WGMM is a versatile genetic map for marker assisted breeding, fine mapping and cloning of genes and quantitative trait loci, developing new genetic markers and maps, genome-wide association mapping, and genome evolution studies.
authors: Plant Genome Mapping Laboratory, University of Georgia, Athens, Georgia 30605.
authors: Zining
authors: Z
authors: Wang
authors: Dong
authors: D
authors: Zhang
authors: Xiyin
authors: X
authors: Wang
authors: Xu
authors: X
authors: Tan
authors: Hui
authors: H
authors: Guo
authors: Andrew H
authors: AH
authors: Paterson
mesh_terms: D002874:Chromosome Mapping; D032461:Chromosomes, Plant / Q000235:genetics; D018744:DNA, Plant / Q000235:genetics*; D008040:Genetic Linkage; D005819:Genetic Markers; D018745:Genome, Plant; D003368:Gossypium / Q000235:genetics*; D018895:Microsatellite Repeats; D012150:Polymorphism, Restriction Fragment Length; D040641:Quantitative Trait Loci; D017422:Sequence Analysis, DNA
chemical_list: D018744:DNA, Plant; D005819:Genetic Markers
keywords: inversions; quantitative trait loci; resistance gene analog; restriction fragment length polymorphism; simple sequence repeat
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