title: 3D reconstruction of skin pathological tissue: the understanding of microrelief pattern and dermal ridge.
abstract: OBJECTIVE
  Most studies about the structures of the human skin have been on the general histologic features of the skin. The purpose of this study was to understand the relationship between the microrelief (MR) pattern and histologic structure of the human skin, and to find the usefulness of the three-dimensional reconstruction (3DR) technique of pathological skin tissue.
  Human skin specimens were obtained from the medial forearm, abdomen, and volar aspects of the finger tips of cadavers. Two-dimensional surface-viewed images of the skin showing MR patterns were obtained using dry dermoscopy. Histologic structures of the skin were evaluated by 3D images obtained using the 3DR technique.
  
  
  RESULTS
  MR was deeper and wider in the abdomen than in the medial side of the forearm. In the medial side of the forearm, 10.27 rete ridges were distributed in a plateau, on average. In the abdomen, about 14.37 rete ridges were distributed in a plateau. From 3DR technique, MR pattern thought to be a superordinate concept to rete ridges.
  
  
  CONCLUSIONS
  The 3DR technique was useful and may allow a better understanding of the pathogenetic changes in the skin surface in aging skin.
authors: Department of Dermatology, College of Medicine, Korea University, Seoul, Korea.
authors: Ga Na
authors: GN
authors: Oh
authors: Jung Hee
authors: JH
authors: Yoon
authors: Hee Sang
authors: HS
authors: Kye
authors: Dai Hyun
authors: DH
authors: Kim
authors: Jong Yeob
authors: JY
authors: Kim
authors: Jae Eun
authors: JE
authors: Choi
authors: Soo Hong
authors: SH
authors: Seo
authors: Young Chul
authors: YC
authors: Kye
authors: Hyo Hyun
authors: HH
authors: Ahn
authors: Im Joo
authors: IJ
authors: Rhyu
mesh_terms: D000328:Adult; D000465:Algorithms; D002102:Cadaver; D046169:Dermoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012867:Skin / Q000473:pathology*; D013499:Surface Properties
keywords: 3D reconstruction; dermal ridge; skin microrelief pattern