title: Chronic inflammatory diseases and the Acute Respiratory Distress Syndrome (ARDS).
abstract: The Acute Respiratory Distress Syndrome (ARDS) is a highly fatal pro-inflammatory oxidative respiratory disease. Relatively recently, the modulating effects of chronic inflammatory processes on ARDS susceptibility have been recognized in a number of clinical studies. Herein, we briefly review some of the chronic conditions that have been reported to increase (cigarette smoking and alcohol abuse) or decrease (diabetes and obesity) susceptibility to ARDS. We also propose some potential pathways that may hold clues regarding the pathogenesis and/or therapy for ARDS.
authors: Ana
authors: A
authors: Fernandez-Bustamante
authors: University of Colorado SOM, Dept. of Anesthesiology & Webb-Waring Center, 12631 E 17th Ave, AO-1, R2012, MS 8202, Aurora, CO, 80045, USA. Ana.Fernandez-Bustamante@ucdenver.edu.
authors: John E
authors: JE
authors: Repine
mesh_terms: D000437:Alcoholism / Q000150:complications; D000818:Animals; D002908:Chronic Disease; D003920:Diabetes Mellitus / Q000378:metabolism; D004198:Disease Susceptibility; D006801:Humans; D007249:Inflammation / Q000150:complications / Q000503:physiopathology*; D009765:Obesity / Q000378:metabolism; D012128:Respiratory Distress Syndrome / Q000209:etiology / Q000503:physiopathology*; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects