title: Thoracoabdominal aortic aneurysm: hybrid repair outcomes.
abstract: BACKGROUND
  Thoracoabdominal aortic aneurysms (TAAA) remain amongst the most formidable of surgical challenges, particularly degenerative aneurysms in the elderly population with concomitant pulmonary disease. This report presents an update of our robust single-institution experience with "hybrid" TAAA repair including complete visceral debranching and endovascular aneurysm exclusion in high-risk patients.
  
  
  METHODS
  Between March 2005 and June 2012, 58 patients underwent extra-anatomic debranching of all visceral vessels followed by aneurysm exclusion via endovascular means at a single institution. The median number of visceral vessels bypassed was 4. The debranching and endovascular portions of the procedure were performed as a single stage in the initial 33 patients and as a staged approach in the most recent n=25 cases.
  
  
  RESULTS
  Median patient age was 69.0 years; 50% were female. All had significant co-morbidity and were considered suboptimal candidates for conventional open surgical repair. Mean aortic diameter was 6.7¡À1.2 cm. Thirty-day/in-hospital rates of death, stroke, and permanent paraparesis/paraplegia were 9%, 0%, and 4%, respectively; in the most recent 25 patients undergoing staged repair these rates were 4%, 0%, and 0%. Over a mean follow-up of 26¡À21 months, visceral graft patency is 95.3%; all occluded limbs were to renal vessels and none resulted in permanent dialysis. Two patients (3%) have required re-intervention, one for type Ib and one for type III endoleak. Five-year freedom from re-intervention was 94%. Kaplan-Meier overall survival was 78% at 1 year and 62% at 5 years, with a 5-year aorta-specific survival of 87%.
  
  
  CONCLUSIONS
  These updated results continue to support hybrid TAAA repair via complete visceral debranching and endovascular aneurysm exclusion as a good option for elderly high-risk patients less suited to conventional open repair. A staged approach to debranching and endovascular aneurysm exclusion appears to yield optimal results.
authors: Divisions of Cardiovascular and Thoracic Surgery;
authors: G Chad
authors: GC
authors: Hughes
authors: Nicholas D
authors: ND
authors: Andersen
authors: Jennifer M
authors: JM
authors: Hanna
authors: Richard L
authors: RL
authors: McCann
keywords: Thoracoabdominal aortic aneurysms (TAAA); endovascular aneurysm; pulmonary disease
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