title: Young people at risk of psychosis: their subjective experiences of monitoring and cognitive behaviour therapy in the early detection and intervention evaluation 2 trial.
abstract: OBJECTIVE
  To explore participants' experiences of 'enhanced monitoring' and cognitive behaviour therapy (CBT) within a randomized controlled trial evaluating early detection and prevention of psychosis ('early detection and intervention evaluation [EDIE] 2').
  
  
  METHODS
  Semi-structured qualitative interviews were conducted with a sample of participants at the end of their involvement with the trial.
  
  
  METHODS
  Ten young people were interviewed; six males and four females, with a mean age of 27.5. Nine participants identified themselves as White British and one Black British. All participants had received 'enhanced monitoring' during the trial, and 8 of 10 also received CBT. Interviews were transcribed verbatim and analysed using thematic analysis to identify central themes within and among participants' accounts.
  
  
  RESULTS
  Three super-ordinate thematic areas were identified: 'a chance to talk', monitoring-specific themes, and CBT-specific themes. The central theme ('a chance to talk') was drawn from across all participants' accounts and represents the most consistently valued attribute of participants' experiences of the EDIE 2 trial. Sub-themes of this topic were identified as follows: interpersonal engagement, informality and normalization, and 'opening up'. Sub-themes related to monitoring include the following: clarity and reassurance, 'a therapeutic process', and challenges. CBT experience was most consistently conceptualized as 'rethinking things', and two additional CBT-specific sub-themes were identified: hard work and moving forward.
  
  
  CONCLUSIONS
  Our findings suggest that for young people at risk of psychosis, a normalizing psychosocially oriented assessment and monitoring process may have benefits for many, while CBT may help to reduce the negative impact of unusual psychological experiences for both the short- and long term.
  
  
  CONCLUSIONS
  Young people considered at risk of psychosis highly value normalizing, collaborative, and flexible approaches when engaging with research or clinical staff. All of our participants highlighted the primary value of their engagement with staff members as having a 'chance to talk' about their experiences and difficulties. CBT seems to be widely acceptable among 'at-risk' participants, though further research is required to establish the 'key ingredients' of effective CBT for 'at-risk' individuals. Valued CBT-related outcomes highlighted by participants included improved psychosocial understanding of their difficulties, improved coping ability, and greater optimism for the future.
authors: Greater Manchester West Mental Health NHS Foundation Trust, Manchester, UK; The University of Manchester, UK.
authors: Rory E
authors: RE
authors: Byrne
authors: Anthony P
authors: AP
authors: Morrison
mesh_terms: D000328:Adult; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D042241:Early Diagnosis; D061345:Early Medical Intervention / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care; D011369:Professional-Patient Relations; D011618:Psychotic Disorders / Q000175:diagnosis / Q000517:prevention & control / Q000523:psychology; D012306:Risk; D055815:Young Adult
keywords: Cognitive behaviour therapy; Early detection; Psychosis