title: Stereocontrolled synthesis of (E,Z)-dienals via tandem Rh(I)-catalyzed rearrangement of propargyl vinyl ethers.
abstract: A novel Rh(I)-catalyzed approach to functionalized (E,Z) dienals has been developed via tandem transformation where a stereoselective hydrogen transfer follows a propargyl Claisen rearrangement. Z-Stereochemistry of the first double bond suggests the involvement of a six-membered cyclic intermediate whereas the E-stereochemistry of the second double bond stems from the subsequent protodemetalation step giving an (E,Z)-dienal.
authors: Department of Chemistry & Biochemistry, Florida State University, Tallahassee, Florida 32306, USA.
authors: Dinesh V
authors: DV
authors: Vidhani
authors: Marie E
authors: ME
authors: Krafft
authors: Igor V
authors: IV
authors: Alabugin