title: Effect of synthetic pyrethroid pesticide exposure during pregnancy on the growth and development of infants.
abstract: Antenatal urine of 497 pregnant women was collected in the Department of Gynecology and Obstetrics of a county hospital in Jiaozuo, Henan. The content of the main metabolites of synthetic pyrethroid pesticides in urine were determined. After 1 year, physical development indices of 1-year old infants, such as height, weight, and head and chest circumference, were measured. The neural and mental development of the infants was assessed by the Development Screen Test (DST) scale. We observed that the level of synthetic pyrethroid pesticide exposure was negatively related to the neural and mental development of infants (β = -0.1527, P < 0.05). Therefore, direct or indirect exposure to synthetic pyrethroid pesticides should be avoided during pregnancy.
authors: Department of Neurology, The Ninety-first Central Hospital of PLA, Jiaozuo, Henan Province, China. xuezhanyou@126.com
authors: Zhanyou
authors: Z
authors: Xue
authors: Xiaoqiong
authors: X
authors: Li
authors: Qian
authors: Q
authors: Su
authors: Li
authors: L
authors: Xu
authors: Peng
authors: P
authors: Zhang
authors: Zhenyu
authors: Z
authors: Kong
authors: Jianhui
authors: J
authors: Xu
authors: Junfang
authors: J
authors: Teng
mesh_terms: D000293:Adolescent; D000328:Adult; D002657:Child Development / Q000187:drug effects*; D002681:China; D002658:Developmental Disabilities / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D001523:Mental Disorders / Q000139:chemically induced; D008875:Middle Aged; D009420:Nervous System / Q000187:drug effects / Q000254:growth & development; D009422:Nervous System Diseases / Q000139:chemically induced; D010575:Pesticides / Q000633:toxicity* / Q000652:urine; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000139:chemically induced*; D011722:Pyrethrins / Q000633:toxicity* / Q000652:urine; D055815:Young Adult
chemical_list: D010575:Pesticides; D011722:Pyrethrins
keywords: growth and development; infants; neural development; pregnancy; synthetic pyrethroid pesticide