title: The effects of simple and radical hysterectomy and radiotherapy on lower urinary tract symptoms and urodynamics.
abstract: OBJECTIVE
  To evaluate effects of simple/radical hysterectomy, radiotherapy, and their combination on lower urinary tract symptoms (LUTS) and urodynamics.
  
  
  METHODS
  Four groups were formed as simple hysterectomy; Group 1 (n = 20), Type-II hysterectomy; Group 2 (n = 11), Type-II hysterectomy + radiotherapy; Group 3 (n = 16), radiotherapy; Group 4 (n = 20). LUTS, bladder diary, pad test, Q-tip test, stress-test, urodynamics, bladder-wall-thickness measurement, King's Health Questionnaire (KHQ) performed prior and at six and 18 months after treatment.
  
  
  RESULTS
  Pre-treatment prevalence of LUTS was higher in Group 1 and decreased at six and 18 months. LUTS increased in Groups 2, 3, and 4 at six months; some of the symptoms decreased to pre-treatment levels at 18 months. Quality of life improved in Group 1 and worsened in the others. Maximum bladder capacity increased in Group 1 and decreased in Groups 2 and 3. Bladder-wall-thickness, maximum detrusor pressures increased, urine sensation decreased in Groups 2 and 4. Maximum vesical pressure increased and compliance decreased in Groups 2 and 3.
  
  
  CONCLUSIONS
  LUTS may decrease after simple hysterectomy. Radical hysterectomy and radiotherapy result in voiding dysfunction; however some of the symptoms may decrease to pre-treatment levels during follow-up.
authors: Istanbul University, Istanbul Medical Faculty, Department of Obstetrics and Gynecology, Istanbul, Turkey.
authors: E
authors: E
authors: Gilbaz
authors: F
authors: F
authors: Gungor Ugurlucan
authors: I
authors: I
authors: Aslay
authors: O
authors: O
authors: Yalcin
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects*; D059411:Lower Urinary Tract Symptoms / Q000209:etiology*; D008875:Middle Aged; D009367:Neoplasm Staging; D011788:Quality of Life; D011878:Radiotherapy / Q000009:adverse effects; D014563:Urodynamics / Q000528:radiation effects; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000523:psychology / Q000532:radiotherapy* / Q000601:surgery*