title: Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor: Case report and literature review.
abstract: Hereditary angioedema (HAE) is a rare disorder caused by a deficiency of C1 esterase inhibitor. Minor trauma and emotional stress are the most common initiating events leading to contact system activation and excessive uncontrolled bradykinin release. This manifests as angioedema, a vascular reaction of the deeper layers of the skin and mucous membranes, with vasodilatation and increased permeability resulting in tissue swelling. Severe angioedema can occur in the perioperative period, leading to fatal airway obstruction. We describe the anaesthetic management of a child with HAE for dental rehabilitation and provide an review of the relevant literature.
authors: Department of Anaesthesia & Intensive Care, Sultan Qaboos University Hospital, Muscat, Oman.
authors: Aravind
authors: A
authors: Narayanan
authors: Rohit R
authors: RR
authors: Date
authors: Sanathkumar
authors: S
authors: Birur
authors: Pradipta
authors: P
authors: Bhakta
authors: Sinnakirouchenane
authors: S
authors: Srinivasan
keywords: Anesthesia; C1 esterase inhibitor deficiency; Case Report; Hereditary angioedema; Oman
references: Drugs. 2008;68(18):2561-73
references: 19093699
references: J Allergy Clin Immunol. 2008 Feb;121(2 Suppl):S398-401; quiz S419
references: 18241690
references: Arch Intern Med. 2003 May 26;163(10):1229-35
references: 12767961
references: Ann Allergy Asthma Immunol. 2007 Apr;98(4):383-8
references: 17458436
references: Am J Rhinol Allergy. 2011 Nov-Dec;25(6):373-8
references: 22185738
references: Anesth Analg. 1998 Aug;87(2):480-8
references: 9706955
references: Clin Cosmet Investig Dermatol. 2011;4:61-8
references: 21760740
references: Allergy. 2012 Feb;67(2):147-57
references: 22126399
references: Am J Rhinol Allergy. 2011 Nov-Dec;25(6):379-82
references: 22185739
references: Ann Allergy Asthma Immunol. 2012 Dec;109(6):395-402
references: 23176876
references: J Am Dent Assoc. 2003 Aug;134(8):1088-94
references: 12956349
references: Can J Anaesth. 1987 Jan;34(1):76-8
references: 3829289
references: N Engl J Med. 2008 Sep 4;359(10):1027-36
references: 18768946
references: Trends Mol Med. 2009 Feb;15(2):69-78
references: 19162547
references: Arch Intern Med. 2001 Mar 12;161(5):714-8
references: 11231704
references: Allergy Asthma Clin Immunol. 2010 Jul 28;6(1):19
references: 20667122
references: J Allergy Clin Immunol. 2012 Sep;130(3):692-7
references: 22841766
references: Anaesthesia. 2010 Jan;65(1):74-7
references: 19849675
references: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Feb;109(2):168-72
references: 20123405
references: Clin Ther. 2012 Mar;34(3):623-30
references: 22386830
references: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Jul;112(1):58-64
references: 21601496
references: Pediatrics. 2007 Sep;120(3):e713-22
references: 17724112
references: Lancet. 2012 Feb 4;379(9814):474-81
references: 22305226
references: Am J Med. 2012 Sep;125(9):938.e1-7
references: 22800873
references: Allergy Asthma Clin Immunol. 2010 Jul 28;6(1):24
references: 20667127