title: [Feasibility of patient-injected anticoagulation therapy: the GRANTED experience].
abstract: BACKGROUND
  Injectable anticoagulation therapy is indicated for several months following diagnosis of venous thromboembolic disease (VTE) in a context of active neoplasia. Certain studies have shown an improvement in patient compliance using self-injections.
  
  
  OBJECTIVE
  Allow patients to safely make their own injections of anticoagulants after checking their aptitude and motivation.
  
  
  METHODS
  At the prescribing physician's request, the GRANTED network provided patients and/or the resource person with specific education and training. The educational program was proposed to patients with an indication for a treatment for at least 3 months. After becoming familiar with the injection material and its manipulation, the patient and/or resource person performed sham injections on test materials. Patients were then allowed to decide for themselves whether or not to participate in the self-injection protocol. The prescribing physician received a report from the training team.
  
  
  RESULTS
  From November 2010 to July 2012, 39 patients participated in the educational program, generally in a context of vitamin K antagonist prescriptions. Sixteen of these patients had a neoplasia. The educational program corrected erroneous or imprecise points of information, particularly concerning syringe purging.
  
  
  CONCLUSIONS
  The education program proved to be interesting for points other than those initially foreseen and allowed the team to rectify a certain number of erroneous messages unrecognized by the prescribing physicians. This result goes in line with the need for accompanying patients who have a prescription for self-injections and also emphasizes the need for careful follow-up.
authors: Unité de médecine vasculaire, clinique de médecine vasculaire, CHU de Grenoble, BP 217, 38043 Grenoble cedex 09, France. Electronic address: JYver@chu-grenoble.fr.
authors: J
authors: J
authors: Yver
authors: L
authors: L
authors: Desbat
authors: E
authors: E
authors: Nozières
authors: B
authors: B
authors: Satger
authors: M
authors: M
authors: Fontaine
authors: S
authors: S
authors: Blaise
authors: G
authors: G
authors: Pernod
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000008:administration & dosage*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications; D010353:Patient Education as Topic; D012646:Self Administration; D054556:Venous Thromboembolism / Q000188:drug therapy* / Q000517:prevention & control; D014812:Vitamin K / Q000037:antagonists & inhibitors
chemical_list: D000925:Anticoagulants; D014812:Vitamin K
keywords: Anticoagulants; Auto-injection; Healthcare network; Neoplasia; Néoplasie; Réseau de santé; Self-injection; Therapeutic education; Traitements anticoagulants; Éducation thérapeutique