title: Corticosteroid therapy improves the outcome of semen analysis in an oligozoospermic patient with epididymal sarcoidosis.
abstract: Sarcoidosis is a multisystem, inflammatory disorder characterized by the presence of noncaseating epithelioid granulomas. Sarcoidosis can involve the genitourinary system by affecting the kidney and genitals. Most characteristic genital lesions proceed to granuloma and can comprise the epididymis, testis, and vas deferens. Few case reports have been published on this rare entity. We report a case in which a man presented with bilateral epididymal sarcoidosis and severe oligospermia. Corticosteroid treatment, which was applied in gradually decreasing doses for 6 months, dissolved the testicular granuloma. Consequently, semen analysis demonstrated a significant increase in the sperm count to within normal limits.
authors: Urology II Clinics, Kartal Teaching and Research Hospital, Istanbul, Turkey.
authors: Onder
authors: O
authors: Canguven
authors: Muhsin
authors: M
authors: Balaban
authors: Ahmet
authors: A
authors: Selimoglu
authors: Selami
authors: S
authors: Albayrak
keywords: Infertility; Sperm count; Spermatogenesis; Testicular diseases
references: Urology. 1974 Jun;3(6):750-4
references: 4836337
references: QJM. 2003 Aug;96(8):553-61
references: 12897340
references: Intern Med. 2003 Jan;42(1):92-7
references: 12583627
references: Fertil Steril. 1998 Oct;70(4):777-9
references: 9797115
references: Radiographics. 2002 Jan-Feb;22(1):189-216
references: 11796908
references: Fertil Steril. 2009 May;91(5):1957.e1-4
references: 19249026
references: J Urol. 1993 Jan;149(1):134-6
references: 8417196
references: J Urol. 1986 Feb;135(2):380-1
references: 3944878
references: Sarcoidosis Vasc Diffuse Lung Dis. 2007 Sep;24(2):95-101
references: 18496978
references: Fertil Steril. 2004 Dec;82(6):1672-4
references: 15589877