title: Primary malignant melanoma of the esophagus: a rare and aggressive disease.
abstract: Primary malignant melanoma of the esophagus is an uncommon tumor, with approximately 300 cases having been reported thus far. The purpose of this study was to describe a case of a 60 year-old man with a 10 month history of progressive dysphagia and thoracic pain, the investigations of which led to a diagnosis of primary malignant melanoma of the esophagus. The patient underwent a transhiatal esophagectomy with subcarinal lymphadenectomy, and isoperistaltic gastric tube replacement of the esophagus. Nine months after surgery, he developed ischemic colitis, and metastasis in the mesentery was diagnosed. His disease progressed and he died one year after the esophagectomy. A review of the literature was performed.
authors: Departments of Gastroenterology/Pathology, Instituto do Câncer do Estado de São Paulo - ICESP, University of São Paulo School of Medicine, São Paulo, Brazil. ulyssesribeiro@terra.com.br.
authors: Flávio Hiroshi Ananias
authors: FH
authors: Morita
authors: Ulysses
authors: U
authors: Ribeiro
authors: Rubens Antonio Aissar
authors: RA
authors: Sallum
authors: Marcos Roberto
authors: MR
authors: Tacconi
authors: Flávio Roberto
authors: FR
authors: Takeda
authors: Julio Rafael Mariano
authors: JR
authors: da Rocha
authors: Giovanna de Sanctis Callegari
authors: Gde S
authors: Ligabó
authors: Evandro Sobrosa
authors: ES
authors: de Melo
authors: Wilson Modesto
authors: WM
authors: Pollara
authors: Ivan
authors: I
authors: Cecconello
mesh_terms: D004938:Esophageal Neoplasms / Q000473:pathology* / Q000601:surgery; D016629:Esophagectomy; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D011183:Postoperative Complications; D011379:Prognosis
references: Ann Thorac Surg. 1997 May;63(5):1461-3
references: 9146346
references: Melanoma Res. 2010 Feb;20(1):59-60
references: 20010440
references: Rev Gastroenterol Peru. 2009 Apr-Jun;29(2):185-90
references: 19609335
references: J Gastroenterol. 2012 Jan;47(1):21-8
references: 22048255
references: Dis Esophagus. 2002;15(3):244-9
references: 12444999
references: Arch Pathol Lab Med. 2008 Oct;132(10):1623-9
references: 18834221
references: Dis Esophagus. 2011 Feb;24(2):109-13
references: 21040150
references: Am J Gastroenterol. 1989 Dec;84(12):1475-81
references: 2688398
references: Am J Gastroenterol. 1996 May;91(5):1048-9
references: 8633555
references: Dis Esophagus. 2000;13(2):172-4
references: 14601912
references: Adv Anat Pathol. 2011 May;18(3):235-52
references: 21490441
references: Hepatogastroenterology. 1999 Jan-Feb;46(25):295-8
references: 10228810
references: J Surg Oncol. 1997 Nov;66(3):201-6
references: 9369967
references: Mod Pathol. 2011 Apr;24(4):495-501
references: 21131919