title: Histologic variants of seminoma mimicking lymphatic malignancies of the testis: a literature review with a report of case series focusing on problems in differential diagnosis.
abstract: We focused on the clinical and morphologic similarities that may cause a misdiagnosis between histologic variants of seminoma and we highlighted the differences between spermatocytic seminoma and high-mitotic rate seminoma or plasmocytic testicular lymphoma or plasmacytoma of the testis. We emphasized on the difficult points in the differential diagnosis, with a critical review of the literature, reporting a case series to discuss problems in differential diagnosis.
authors: Department of Histology and Molecular Diagnostics, University Hospital Careggi, Florence, Italy.
authors: Maria Rosaria
authors: MR
authors: Raspollini
mesh_terms: D000328:Adult; D063194:Adventitia / Q000473:pathology; D000368:Aged; D000369:Aged, 80 and over; D018951:Antigens, CD20 / Q000378:metabolism; D002454:Cell Differentiation; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D008938:Mitosis; D050814:Octamer Transcription Factor-3 / Q000378:metabolism*; D009919:Orchiectomy; D019009:Proto-Oncogene Proteins c-kit / Q000378:metabolism; D018239:Seminoma / Q000175:diagnosis* / Q000473:pathology; D013090:Spermatocytes / Q000473:pathology*; D006848:Testicular Hydrocele / Q000175:diagnosis* / Q000473:pathology; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000473:pathology
chemical_list: D018951:Antigens, CD20; D050814:Octamer Transcription Factor-3; C494174:Pou5f1 protein, mouse; D019009:Proto-Oncogene Proteins c-kit