title: Dipyridamole and paracetamol overdose resulting in multi-organ failure.
abstract: Dipyridamole intoxication is rare and few reports exist amongst the current literature. A case of dipyridamole and paracetamol overdose is described in a previously healthy 58-year-old woman, which resulted in multi-organ failure requiring dialysis, inotropic support, ventilation and extensive surgical intervention for small bowel ischaemia. This case highlights the dangers of an unusually large overdose of a commonly prescribed drug, and reviews current knowledge of dipyridamole intoxication.
authors: Faculty of Medicine, University of Glasgow, UK. cullispaul@gmail.com
authors: P S
authors: PS
authors: Cullis
authors: D
authors: D
authors: Watson
authors: A
authors: A
authors: Cameron
authors: R F
authors: RF
authors: McKee
mesh_terms: D000082:Acetaminophen / Q000506:poisoning*; D018712:Analgesics, Non-Narcotic / Q000506:poisoning*; D003863:Depression / Q000188:drug therapy / Q000523:psychology; D004176:Dipyridamole / Q000506:poisoning*; D062787:Drug Overdose / Q000150:complications* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006760:Hospitalization; D006801:Humans; D007813:Laparotomy; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000139:chemically induced* / Q000188:drug therapy / Q000601:surgery; D016331:Parenteral Nutrition, Home; D010975:Platelet Aggregation Inhibitors / Q000506:poisoning*; D011379:Prognosis; D006435:Renal Dialysis; D012606:Scotland; D013406:Suicide, Attempted; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D018712:Analgesics, Non-Narcotic; D010975:Platelet Aggregation Inhibitors; D000082:Acetaminophen; D004176:Dipyridamole
keywords: Dipyridamole; ischaemic bowel; multi-organ failure; overdose