title: True aneurysm of the peripheral pulmonary artery due to necrotizing giant cell arteritis.
abstract: Pulmonary artery aneurysm in adults is a rare diagnosis. Most cases described in the literature are either associated with congenital heart disease or pulmonal arterial hypertension, respectively, or are not true aneurysms but rather pseudoaneurysms, which are usually iatrogenic. We present the case of a 68-year old female patient with the incidental finding of a true aneurysm of the right peripheral pulmonary artery with a maximum diameter of 4 cm. With increasing aneurysm diameter over time, the decision for a surgical resection was made. Complete resection of the aneurysm including lower lobe resection was performed. Histopathological examination showed necrotizing giant cell arteritis as the underlying cause. The postoperative course was uneventful and no signs of further disease activity were detected. To our knowledge, this is the first reported case of a pulmonary artery aneurysm caused by giant cell arteritis, whereas it should be noted that the distinction between Takayasu arteritis and giant cell arteritis is not clearly defined. Considering the high mortality associated with aneurysm rupture, surveillance is advocated for small aneurysms, whereas for larger aneurysms and those showing signs of progression in size despite medical therapy or even dissection, surgical intervention should be considered.
authors: Division of General Thoracic Surgery, University Hospital of Bern, Bern, Switzerland.
authors: Sven C
authors: SC
authors: Steireif
authors: Gregor J
authors: GJ
authors: Kocher
authors: Florin T F
authors: FT
authors: Gebhart
authors: Ralph A
authors: RA
authors: Schmid
mesh_terms: D000368:Aged; D000783:Aneurysm / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D005260:Female; D013700:Giant Cell Arteritis / Q000473:pathology*; D006801:Humans; D009336:Necrosis / Q000473:pathology; D011651:Pulmonary Artery / Q000473:pathology* / Q000601:surgery; D019616:Thoracic Surgical Procedures
keywords: Giant cell arteritis; Pulmonary artery; Pulmonary artery aneurysm; Takayasu arteritis