title: N-heterocyclic carbene-catalyzed highly enantioselective synthesis of substituted dihydropyranopyrazolones.
abstract: Highly optically pure multisubstituted dihydropyrano[2,3-c]pyrazol-6-(1H)-ones were synthesized via the N-heterocyclic carbene-catalyzed enantioselective [4 + 2] annulation of α-chloroaldehydes and pyrazolone-derived oxodienes.
authors: Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors: Han-Ming
authors: HM
authors: Zhang
authors: Hui
authors: H
authors: Lv
authors: Song
authors: S
authors: Ye
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D006571:Heterocyclic Compounds / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D011714:Pyrans / Q000138:chemical synthesis*; D047069:Pyrazolones / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D006571:Heterocyclic Compounds; D011714:Pyrans; D047069:Pyrazolones; C030011:carbene; D008697:Methane