title: Evaluation of cardiovascular anomalies in patients with asymptomatic turner syndrome using multidetector computed tomography.
abstract: Turner syndrome is well known to be associated with significant cardiovascular abnormalities. This paper studied the incidence of cardiovascular abnormalities in asymptomatic adolescent patients with Turner syndrome using multidetector computed tomography (MDCT) instead of echocardiography. Twenty subjects diagnosed with Turner syndrome who had no cardiac symptoms were included. Blood pressure and electrocardiography (ECG) was checked. Cardiovascular abnormalities were checked by MDCT. According to the ECG results, 11 had a prolonged QTc interval, 5 had a posterior fascicular block, 3 had a ventricular conduction disorder. MDCT revealed vascular abnormalities in 13 patients (65%). Three patients had an aberrant right subclavian artery, 2 had dilatation of left subclavian artery, and others had an aortic root dilatation, aortic diverticulum, and abnormal left vertebral artery. As for venous abnormalities, 3 patients had partial anomalous pulmonary venous return and 2 had a persistent left superior vena cava. This study found cardiovascular abnormalities in 65% of asymptomatic Turner syndrome patients using MDCT. Even though, there are no cardiac symptoms in Turner syndrome patients, a complete evaluation of the heart with echocardiography or MDCT at transition period to adults must be performed.
authors: Department of Pediatrics, Sungae Hospital, Seoul, Korea.
authors: Sun Hee
authors: SH
authors: Lee
authors: Ji Mi
authors: JM
authors: Jung
authors: Min Seob
authors: MS
authors: Song
authors: Seok jin
authors: Sj
authors: Choi
authors: Woo Yeong
authors: WY
authors: Chung
mesh_terms: D000293:Adolescent; D001794:Blood Pressure; D018376:Cardiovascular Abnormalities / Q000150:complications / Q000453:epidemiology; D004562:Electrocardiography; D006801:Humans; D007621:Karyotyping; D061330:Multidetector Computed Tomography; D015995:Prevalence; D014424:Turner Syndrome / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D054079:Vascular Malformations / Q000150:complications / Q000453:epidemiology; D014711:Vertebral Artery / Q000002:abnormalities; D055815:Young Adult
keywords: Adolescent; Cardiovascular Malformation; Multidetector Computed Tomography; Turner Syndrome
references: Pediatr Cardiol. 1999 Mar-Apr;20(2):108-12
references: 9986886
references: J Pediatr. 1963 Oct;63:577-88
references: 14074416
references: J Med Genet. 1980 Apr;17(2):133-4
references: 7381868
references: J Thorac Imaging. 2009 May;24(2):89-95
references: 19465830
references: Pediatrics. 1964 Jun;33:919-25
references: 14169637
references: Pediatrics. 1998 Jan;101(1):E11
references: 9417175
references: Teratology. 1984 Jun;29(3):355-61
references: 6463900
references: J Clin Endocrinol Metab. 2007 Jan;92(1):10-25
references: 17047017
references: Growth Horm IGF Res. 2006 Jul;16 Suppl A:S103-8
references: 16624607
references: J Vasc Surg. 1991 Mar;13(3):452-8
references: 1999868
references: Am J Cardiol. 1989 Sep 1;64(8):507-12
references: 2773795
references: Medicine (Baltimore). 1958 Sep;37(3):217-79
references: 13577293
references: Radiol Clin North Am. 2011 Sep;49(5):997-1010
references: 21889018
references: Pediatrics. 1990 Aug;86(2):273-6
references: 2371102
references: Pediatrics. 1998 Jul;102(1):e12
references: 9651464
references: J Pediatr. 1986 Aug;109(2):302-5
references: 3734967
references: Am J Med Sci. 1989 Apr;297(4):260-2
references: 2650544
references: Eur J Pediatr. 1988 Nov;148(2):101-3
references: 3069469
references: Korean J Radiol. 2010 Jan-Feb;11(1):4-18
references: 20046490
references: Europace. 2008 May;10(5):588-90
references: 18319265
references: J Cardiovasc Surg (Torino). 1997 Jun;38(3):257-9
references: 9219475
references: J Pediatr. 1998 Nov;133(5):688-92
references: 9821430
references: Helv Paediatr Acta. 1988 Aug;43(1-2):25-31
references: 3170246
references: Australas Radiol. 1992 Aug;36(3):204-9
references: 1445102
references: Pediatrics. 1988 Mar;81(3):445-51
references: 3344189
references: Circulation. 2004 Sep 21;110(12):1694-700
references: 15353492
references: Proc (Bayl Univ Med Cent). 2008 Apr;21(2):115-9
references: 18382748
references: Eur J Endocrinol. 2004 Dec;151(6):657-87
references: 15588233