title: Successful treatment of Erdheim-Chester disease by interleukin-1 receptor antagonist protein.
abstract: Erdheim-Chester disease is a rare non-langerhans systemic histiocytosis of unknown origin, associated with bone diseases and severe visceral complications. Therapies have been disappointing. A recombinant form of interleukin-1 receptor antagonist (anakinra) has been used in a few cases when usual treatment fails. We report a new case of successfully interleukin-1 receptor antagonist treatment in Erdheim-Chester disease.
authors: Inserm UMR1033, université de Lyon, Hospices Civils de Lyon, Department of rheumatology, Pavillon F, hospital Edouard-Herriot, 5, place d'Arsonval, 69003 Lyon, France.
authors: Audrey
authors: A
authors: Courcoul
authors: Inserm UMR1033, université de Lyon, Hospices Civils de Lyon, Department of rheumatology, Pavillon F, hospital Edouard-Herriot, 5, place d'Arsonval, 69003 Lyon, France.
authors: Emmanuelle
authors: E
authors: Vignot
authors: Inserm UMR1033, université de Lyon, Hospices Civils de Lyon, Department of rheumatology, Pavillon F, hospital Edouard-Herriot, 5, place d'Arsonval, 69003 Lyon, France. Electronic address: roland.chapurlat@chu-lyon.fr.
authors: Roland
authors: R
authors: Chapurlat
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D031249:Erdheim-Chester Disease / Q000188:drug therapy*; D006801:Humans; D053590:Interleukin 1 Receptor Antagonist Protein / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
chemical_list: D018501:Antirheumatic Agents; D053590:Interleukin 1 Receptor Antagonist Protein
keywords: Anakinra; Erdheim-Chester disease; Histiocytosis; Interleukin-1 receptor antagonist protein