title: [Treatment of irritable bowel syndrome by Chinese medicine and pharmacy: an analysis of data mining on experiences of experts].
abstract: OBJECTIVE
  The pathogenesis of irritable bowel syndrome (IBS), a functional gastrointestinal disorder, is poorly understood. Treatment by Chinese medicine and pharmacy (CMP) is superior to treatment by Western medicine (WM). Therefore, we aimed to analyze Chinese medical experts' experiences in treating IBS by data mining.
  
  
  METHODS
  By retrieving related literatures from 1994 to 2012 from CNKI, we chose proved cases and screened effective medical records to establish a database using structural electronic medical case collecting system and data mining. The thinking ways of modern physicians in diagnosis and treatment of IBS were analyzed.
  
  
  RESULTS
  Totally 116 medical cases from 46 Chinese medical experts were recruited and analyzed. Results showed that Gan depression and Pi deficiency were most basic syndrome elements. In addition, cold dampness, damp heat, yang deficiency, and Shen deficiency were main elements for the development of diarrhea predominant IBS (IBS-D). Qi stagnation, yin deficiency, qi deficiency, and blood stasis were main elements for the development of constipation predominant IBS (IBS-C). Soothing Gan-qi and strengthening Pi was the most important treatment method. White peony root, prepared atractylodes, prepared licorice, tangerine peel, poria, bupleurum, Radix sileris, lanceolata, and Radix aucklandiae were the most common Chinese herbs used in treating IBS.
  
  
  CONCLUSIONS
  (1) Gan depression and Pi deficiency was the main pathogenesis for IBS. Diagnosis and treatment of IBS should be performed clinically according to its development. Tongxie Yao-fang should be used as the basic prescription with modification according to syndrome differentiation. (2) Data mining will have a wide application prospect in studying medical cases.
authors: Graduate School, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors: Bei-Hua
authors: BH
authors: Zhang
authors: Rui
authors: R
authors: Gao
authors: Zhen-Hua
authors: ZH
authors: Li
authors: Bao-Shuang
authors: BS
authors: Li
authors: Feng-Yun
authors: FY
authors: Wang
authors: Xu-Dong
authors: XD
authors: Tang
mesh_terms: D057225:Data Mining; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000175:diagnosis / Q000188:drug therapy; D008516:Medicine, Chinese Traditional / Q000379:methods*; D008517:Phytotherapy / Q000379:methods*