title: Coronary arteries bypass grafting surgery in elderly patients.
abstract: BACKGROUND
  The incidence of coronary artery bypass grafting surgery (CABG) in elderly patients has been increasing. There are contradictory reports on the early outcome of elderly coronary artery patients as compared with their young counterparts. We designed this retrospective study to address this issue.
  
  
  METHODS
  We retrospectively analyzed the results of 1489 on-pump CABG cases performed at our hospital during a 4.5-year period. Perioperative data such as demographic, medical, clinical, operative, and postoperative variables were collected and compared between patients 70 years old or younger (Group A, n = 1164) and patients above 70 years of age (Group B, n = 325). Statistical analysis was performed using the t-test for the continuous and the X(2) tests for the categorical variables. Significant variables according to the univariate analysis (X(2) and t-test) were further analyzed using multivariate logistic regression analysis.
  
  
  RESULTS
  The variables of weight (P value < 0.001), preoperative PO2 (P value = 0.005), ejection fraction > 30% (P value = 0.001), body surface area (P value = 0.003), and hypercholesterolemia (P value = 0.007) were higher in Group A, whereas preoperative myocardial infarction (P value < 0.001), postoperative low cardiac output syndrome (P value = 0.019), emergent surgery (P value = 0.003), inotropic drug use (P value < 0.001), preoperative heparin use (P value < 0.001), re-exploration for bleeding (P value = 0.015), hospital stay (P value < 0.001), low ejection fraction (≤ 30%) (P value = 0.001), preoperative creatinine > 1.5 mg/dl (P value < 0.001), chronic obstructive pulmonary disease (P value < 0.001), intra-aortic balloon pump use (P value < 0.001), infection (P value < 0.001), pulmonary complications (P value < 0.001), atrial fibrillation (P value < 0.001), postoperative renal complications (P value < 0.001), and death (P value = 0.012) were more frequent in Group B.
  
  
  CONCLUSIONS
  CABG in the elderly patients had certain surgical risks such as chronic obstructive pulmonary disease, preoperative myocardial infarction, emergent surgery, and death. Also, postoperative complications such as pulmonary complications, inotropic drug use, intra-aortic balloon pump use, and infection were more frequent in the elderly than in the younger patients.
authors: Imam Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
authors: Feridoun
authors: F
authors: Sabzi
authors: Hashem
authors: H
authors: Kazerani
authors: Arash
authors: A
authors: Jalali
authors: Mojgan
authors: M
authors: Samadi
authors: Fahime
authors: F
authors: Ghasemi
keywords: Aged; Coronary artery bypass; Treatment outcome
references: Am Rev Respir Dis. 1973 Oct;108(4):879-85
references: 4741883
references: Ann Thorac Surg. 1991 Jun;51(6):983-6
references: 2039331
references: Aust N Z J Med. 1985 Feb;15(1):27-32
references: 3859260
references: Clin Pharm. 1986 Jan;5(1):55-8
references: 3485028
references: Ann Thorac Surg. 1994 Aug;58(2):445-50; discussion 450-1
references: 8067847
references: Anadolu Kardiyol Derg. 2002 Mar;2(1):26-34
references: 12101791
references: CMAJ. 2001 Sep 18;165(6):759-64
references: 11584563
references: JAMA. 1992 May 6;267(17):2344-8
references: 1564774
references: Thorac Cardiovasc Surg. 1995 Jun;43(3):129-33
references: 7570563
references: Cardiol J. 2012;19(6):618-24
references: 23224925
references: Ann Thorac Surg. 1981 Jun;31(6):496-501
references: 6972746
references: J Am Coll Cardiol. 1983 Feb;1(2 Pt 1):383-90
references: 6600758
references: J Thorac Cardiovasc Surg. 1991 Jan;101(1):56-65
references: 1986170
references: Prog Cardiovasc Dis. 1974 Mar-Apr;16(5):469-95
references: 4602879
references: JAMA. 2004 Apr 14;291(14):1720-9
references: 15082699
references: Ann Surg. 1997 Oct;226(4):501-11; discussion 511-3
references: 9351718
references: Scand J Thorac Cardiovasc Surg. 1995;29(2):63-9
references: 8643928
references: J Cardiothorac Vasc Anesth. 2005 Oct;19(5):583-8
references: 16202890
references: Eur J Cardiothorac Surg. 2012 Nov;42(5):e102-7
references: 22922696
references: Ann Thorac Surg. 1993 Sep;56(3):539-49
references: 8379728
references: Acta Cardiol. 2013 Feb;68(1):11-8
references: 23457904
references: J Thorac Cardiovasc Surg. 1982 Aug;84(2):219-23
references: 6980329
references: Ann Surg. 1998 Sep;228(3):297-306
references: 9742913
references: CMAJ. 2000 Apr 4;162(7):1005-6
references: 10763400
references: Ann Thorac Surg. 1983 Oct;36(4):437-43
references: 6605126
references: Circulation. 1987 Nov;76(5 Pt 2):V6-12
references: 3499259
references: Isr J Med Sci. 1996 Dec;32(12):1322-5
references: 9007182
references: Ann Thorac Surg. 1998 Jul;66(1):60-7
references: 9692439
references: N Engl J Med. 1988 Jul 21;319(3):131-6
references: 3386692
references: Prog Cardiovasc Dis. 1989 Mar-Apr;31(5):367-78
references: 2646657
references: J Thorac Cardiovasc Surg. 1990 Jan;99(1):92-5; discussion 95-6
references: 2294368
references: Rev Bras Cir Cardiovasc. 2012 Dec;27(4):600-6
references: 23515733
references: Circulation. 1983 Sep;68(3 Pt 2):II190-9
references: 6603283
references: Cardiology. 1992;80(3-4):215-25
references: 1511468
references: J Am Coll Cardiol. 2012 Nov 20;60(21):2150-7
references: 23153843
references: Ann Thorac Surg. 1985 Jun;39(6):552-7
references: 3873921
references: Asian Cardiovasc Thorac Ann. 2009 Jun;17(3):253-8
references: 19643848
references: J Thorac Cardiovasc Surg. 1980 Dec;80(6):876-87
references: 6968859
references: Eur J Cardiothorac Surg. 1999 Jan;15(1):61-6
references: 10077375
references: Circulation. 1990 Nov;82(5 Suppl):IV229-36
references: 2225409
references: Cleve Clin J Med. 1988 Jan-Feb;55(1):23-34
references: 3257723
references: Am Surg. 1993 Sep;59(9):564-8
references: 8368661
references: Ann Thorac Surg. 1995 Oct;60(4):1038-43
references: 7574944
references: J Thorac Cardiovasc Surg. 1991 Oct;102(4):532-8
references: 1681137
references: Ann Thorac Surg. 1994 Nov;58(5):1419-26
references: 7979669
references: Ann Thorac Surg. 1994 Oct;58(4):1069-72
references: 7944752
references: Ann Thorac Surg. 2001 Feb;71(2):591-6
references: 11235712
references: Ann Thorac Surg. 1995 Oct;60(4):1033-7
references: 7574943
references: Ann Thorac Surg. 1996 May;61(5):1323-7; discussion 1328-9
references: 8633935
references: CMAJ. 1999 Mar 23;160(6):823-5
references: 10189429
references: J Thorac Cardiovasc Surg. 1990 Sep;100(3):338-42
references: 2391970
references: Am J Surg. 1992 Nov;164(5):517-21
references: 1443380