title: [Next-generation sequencing].
abstract: Next generation or massive parallel sequencing (MPS) is a rapidly advancing method in molecular genetics that will bring significant changes in the personalized medicine field. In this review we briefly describe major types of MPS, including whole-genome, -exome, -transcriptome and amplicon sequencing. We also present an overview of the advantages, drawbacks and possible applications of sequencing technologies available in the Czech Republic.
authors: Laboratoř molekulární genetiky CLIP, Klinika detske hematologie a onkologie 2. LF UK a FN Motol, Praha. eva.fronkova@lfmotol.cuni.cz
authors: Eva
authors: E
authors: Froňková
mesh_terms: D018153:Czech Republic; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D006801:Humans; D008967:Molecular Biology / Q000379:methods*; D057285:Precision Medicine / Q000379:methods*