title: Anesthesia with isoflurane and sevoflurane in the crested serpent eagle (Spilornis cheela hoya): minimum anesthetic concentration, physiological effects, hematocrit, plasma chemistry and behavioral effects.
abstract: The initial goal of this study was to determine the minimum anesthetic concentration (MAC) for isoflurane (ISO) and sevoflurane (SEVO) for the crested serpent eagle. Next, we compared the anesthetic effects of each on the physiological effects, hematocrit, plasma chemistry values and behavior in spontaneously breathing captive adult crested serpent eagles. Sixteen eagles were randomly allocated to two groups for anesthesia with ISO (n=8) or SEVO (n=8). First, we measured the MAC values of ISO and SEVO, and four weeks later, we investigated the effect of each on the physiological effects, hematocrit (HCT) and plasma chemistry values. The MAC values of ISO and SEVO for crested serpent eagles were 1.46 ± 0.30 and 2.03 ± 0.32%, respectively. The results revealed no significant differences between the two anesthetics in induction time, while time of extubation to recovery was significantly shorter with SEVO. A time-related increase in end-tidal CO₂ and decreases in body temperature and respiratory rates were observed during anesthesia with each anesthetic. There were no significant differences between the effect of the two anesthetics on heart rate, hematocrit, plasma chemistry values or respiration, although each caused minor respiration depression. We concluded that SEVO is a more effective inhalant agent than ISO for use in eagles, showing the most rapidest induction and recovery from anesthesia.
authors: Department of Veterinary Medicine, National Chung Hsing University, 250 Kuo-Kuang Road, Taichung, Taiwan 402, R.O.C.
authors: Fang-Tse
authors: FT
authors: Chan
authors: Geng-Ruei
authors: GR
authors: Chang
authors: Hsien-Chi
authors: HC
authors: Wang
authors: Tien-Huan
authors: TH
authors: Hsu
mesh_terms: D000769:Anesthesia, Inhalation / Q000662:veterinary*; D000818:Animals; D001774:Blood Chemical Analysis; D001831:Body Temperature / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D020307:Eagles / Q000097:blood / Q000378:metabolism*; D005260:Female; D006400:Hematocrit; D007530:Isoflurane / Q000494:pharmacology*; D008297:Male; D008738:Methyl Ethers / Q000494:pharmacology*; D020127:Recovery of Function; D056152:Respiratory Rate / Q000187:drug effects; D000077149:Sevoflurane; D018709:Statistics, Nonparametric; D013624:Taiwan; D013997:Time Factors
chemical_list: D008738:Methyl Ethers; D000077149:Sevoflurane; D007530:Isoflurane
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