title: Enantioselective synthesis of 3-hydroxy oxindoles by ytterbium-catalysed decarboxylative addition of β-ketoacids to isatins.
abstract: A ytterbium(III)-indapybox catalysed enantioselective decarboxylative addition reaction of β-ketoacids to isatins is described. The biologically important 3-hydroxy oxindoles were obtained in high yields and excellent enantioselectivities.
authors: School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, China. yiwang@nju.edu.cn.
authors: Zhiqiang
authors: Z
authors: Duan
authors: Jianlin
authors: J
authors: Han
authors: Ping
authors: P
authors: Qian
authors: Zirui
authors: Z
authors: Zhang
authors: Yi
authors: Y
authors: Wang
authors: Yi
authors: Y
authors: Pan
mesh_terms: D002384:Catalysis; D003653:Decarboxylation; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D007510:Isatin / Q000737:chemistry*; D007651:Keto Acids / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D015018:Ytterbium / Q000737:chemistry*
chemical_list: D007211:Indoles; D007651:Keto Acids; D009942:Organometallic Compounds; D007510:Isatin; D015018:Ytterbium