title: Outcome of total knee arthroplasty in hemophilic arthropathy.
abstract: The clinical histories of 45 consecutively performed TKAs in 32 patients with hereditary bleeding disorders were reviewed retrospectively. The mean follow up was 88.7 (range, 24-232) months. The cumulative probability of infection free-survival was 87.8% after 180 months. When removal of component was defined as endpoint, the survival probability was 86.4% after 180 months. In regression analysis no significant independent risk factors for infection or aseptic loosening were identified. The HSS score improved significantly from 45 to 85 points. Hemophilic patients can be considered to be at high risk for prosthetic failure, our study has demonstrated favorable functional results of total knee arthroplasty in hemophilic patients.
authors: Department of Orthopaedics, Medical University of Vienna, Vienna, Austria.
authors: Joannis
authors: J
authors: Panotopoulos
authors: Department of Medicine I, Clinical Division of Haematology and Haemostaseology, Medical University of Vienna, Vienna, Austria.
authors: Cihan
authors: C
authors: Ay
authors: Department of Orthopaedics, Hospital Wels-Grieskirchen, Vienna, Austria.
authors: Klemens
authors: K
authors: Trieb
authors: Department of Orthopaedics, Medical University of Vienna, Vienna, Austria.
authors: Reinhard
authors: R
authors: Schuh
authors: Department of Orthopaedics, Medical University of Vienna, Vienna, Austria.
authors: Reinhard
authors: R
authors: Windhager
authors: Department of Orthopaedics, Medical University of Vienna, Vienna, Austria.
authors: Hugo A
authors: HA
authors: Wanivenhaus
mesh_terms: D000328:Adult; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D025861:Blood Coagulation Disorders, Inherited / Q000150:complications* / Q000628:therapy; D006801:Humans; D007592:Joint Diseases / Q000209:etiology / Q000601:surgery*; D007719:Knee Joint / Q000601:surgery*; D007720:Knee Prosthesis / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure / Q000209:etiology; D016459:Prosthesis-Related Infections / Q000209:etiology; D012086:Reoperation; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
keywords: arthroplasty; haemophilia; hemophilic arthropathy; knee; outcome