title: Non-vascular drug eluting stents as localized controlled drug delivery platform: preclinical and clinical experience.
abstract: Stents occupy an important place in the medical field for their widespread application. They have been used in vascular as well as in non-vascular organs for various reasons. Among vascular stents, development of coronary drug eluting stents (DESs) has completely revolutionised the percutaneous coronary intervention. Similarly, attempts have been made to make use of this modality in non-vascular organs. This paper focuses on the preclinical and clinical experience with drug-eluting non-vascular stents with emphasis on drug delivery systems and regulatory requirements for their development.
authors: Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA 5000, Australia.
authors: Mohsin
authors: M
authors: Shaikh
authors: Flinders Centre for Innovation in Cancer, Flinders University/Flinders Medical Centre, Medical Oncology, Bedford Park, Adelaide, SA 5042, Australia.
authors: Ganessan
authors: G
authors: Kichenadasse
authors: Ian Wark Research Institute, University of South Australia, Mawson Lakes Campus, Mawson Lakes, Adelaide, SA 5095, Australia.
authors: Namita Roy
authors: NR
authors: Choudhury
authors: Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA 5000, Australia.
authors: Ross
authors: R
authors: Butler
authors: Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA 5000, Australia. Electronic address: Sanjay.Garg@unisa.edu.au.
authors: Sanjay
authors: S
authors: Garg
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D018795:Device Approval; D016503:Drug Delivery Systems / Q000295:instrumentation*; D054855:Drug-Eluting Stents; D004867:Equipment Design; D006801:Humans
keywords: Clinical trials; Drug eluting stents; Non-vascular stents; Preclinical studies