title: Hypertension in children with autosomal dominant polycystic kidney disease (ADPKD).
abstract: Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disease, affecting 1 in 1000 individuals. Previously termed "adult polycystic kidney disease", ADPKD is now known to have important clinical manifestations beginning early in life and even in utero. Hypertension is an important risk factor for progressive renal and cardiovascular disease in children with ADPKD and may signify irremediable organ injury. The purpose of this article is to review current knowledge and treatment strategies in hypertension associated with pediatric ADPKD.
authors: PKD Research Group, University of Colorado Anschutz Medical Campus, 13001 E. 17th Place, MSC283, Aurora, Colorado 80045, USA. Melissa.Cadnapaphornchai@ucdenver.edu
authors: Melissa A
authors: MA
authors: Cadnapaphornchai
mesh_terms: D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000209:etiology / Q000503:physiopathology; D002648:Child; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000503:physiopathology; D007668:Kidney / Q000503:physiopathology; D016891:Polycystic Kidney, Autosomal Dominant / Q000150:complications* / Q000503:physiopathology; D012307:Risk Factors