title: A fast Peptide Match service for UniProt Knowledgebase.
abstract: CONCLUSIONS
  We have developed a new web application for peptide matching using Apache Lucene-based search engine. The Peptide Match service is designed to quickly retrieve all occurrences of a given query peptide from UniProt Knowledgebase (UniProtKB) with isoforms. The matched proteins are shown in summary tables with rich annotations, including matched sequence region(s) and links to corresponding proteins in a number of proteomic/peptide spectral databases. The results are grouped by taxonomy and can be browsed by organism, taxonomic group or taxonomy tree. The service supports queries where isobaric leucine and isoleucine are treated equivalent, and an option for searching UniRef100 representative sequences, as well as dynamic queries to major proteomic databases. In addition to the web interface, we also provide RESTful web services. The underlying data are updated every 4 weeks in accordance with the UniProt releases.
  
  
  BACKGROUND
  http://proteininformationresource.org/peptide.shtml.
  
  
  BACKGROUND
  chenc@udel.edu.
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors: Center for Bioinformatics and Computational Biology and Protein Information Resource, University of Delaware, Newark, DE 19711, USA, Protein Information Resource, Georgetown University Medical Center, Washington, DC 20007, USA, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK and Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1211 Geneva 4, Switzerland.
authors: Chuming
authors: C
authors: Chen
authors: Zhiwen
authors: Z
authors: Li
authors: Hongzhan
authors: H
authors: Huang
authors: Baris E
authors: BE
authors: Suzek
authors: Cathy H
authors: CH
authors: Wu
mesh_terms: D030562:Databases, Protein; D020407:Internet; D051188:Knowledge Bases; D010455:Peptides / Q000737:chemistry*; D040901:Proteomics; D057386:Search Engine; D020539:Sequence Analysis, Protein
chemical_list: D010455:Peptides
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