title: Closure of the uterine incision with one or two layers after caesarean section: a randomized controlled study in sheep.
abstract: OBJECTIVE
  To compare the quality of the uterine scar with one or two layer closure after caesarean section by studying biomechanical and pathological properties of the scar.
  
  
  METHODS
  A randomized controlled trial performed on eight term pregnant ewes assigned into two groups during caesarean according to type of uterine closure: single-layer or double-layer. Hysterectomy was performed 8 months after caesarean delivery. Tensile strength of all scars and of unscarred myometrium was measured. Pathological properties of the scars were analyzed histologically.
  
  
  RESULTS
  The force required to reach the yield point was similar between scarred and unscarred myometrium (p=0.96), and between the scars in single-layer and double-layer closure groups (p=0.65). There was a significant increase in fibrosis width on the superficial part of the uterus in the double-layer closure group compared to the single-layer group (p=0.02).
  
  
  CONCLUSIONS
  Double-layer uterine closure modified wound healing without significant change in biomechanical properties.
authors: Department of Obstetrics and Gynecology .
authors: Korine
authors: K
authors: Lapointe-Milot
authors: Edmond
authors: E
authors: Rizcallah
authors: Larissa
authors: L
authors: Takser
authors: Nadia
authors: N
authors: Abdelouahab
authors: Charles
authors: C
authors: Duvareille
authors: Jean-Charles
authors: JC
authors: Pasquier
mesh_terms: D000818:Animals; D002585:Cesarean Section / Q000379:methods*; D002921:Cicatrix / Q000473:pathology*; D005260:Female; D009215:Myometrium / Q000473:pathology*; D011247:Pregnancy; D011897:Random Allocation; D012756:Sheep; D013536:Suture Techniques