title: N-heterocyclic carbene catalyzed regioselective oxo-acyloxylation of alkenes with aromatic aldehydes: a high yield synthesis of α-acyloxy ketones and esters.
abstract: An N-heterocyclic carbene (NHC)-catalyzed reaction of alkenes with aromatic aldehydes providing for a high yield synthesis of α-acyloxy ketones and esters has been described. This unprecedented regioselective oxidative process employs NBS and Et3N in stoichiometric amounts and O2 (1 atm) as an oxidant under ambient conditions in DMSO as a solvent.
authors: Chemical Engineering and Process Development Division, National Chemical Laboratory (CSIR), Pashan Road, Pune, 411008, India. a.sudalai@ncl.res.in.
authors: Rambabu N
authors: RN
authors: Reddi
authors: Pushpa V
authors: PV
authors: Malekar
authors: Arumugam
authors: A
authors: Sudalai
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D000475:Alkenes; D004952:Esters; D006571:Heterocyclic Compounds; D007659:Ketones; C030011:carbene; D008697:Methane; D010100:Oxygen