title: [Hypertrophic cardiomyopathy -- modern state of the problem. Issues of epidemiology and nomenclature, genetics and pathophysiology, variants of course and differential diagnosis].
abstract: The problem of the study of hypertrophic cardiomyopathy (HCM) has preserved its actuality because of high prevalence (1:500), risk of sudden cardiac death (SCD) in individuals of young able-bodied age. Subject of great interest appear problems of search for additional clinical, instrumental and genetic markers, environmental factors which are capable to influence formation of a clinical variant of HCM course, risk of SCD, and prognosis of HCM. Important problem requiring further study appears to be molecular genetic characteristic of the disease. Integrated nomenclature of various forms and variants of course of HCM is essential for elaboration of tactics of management of patients and assessment of results of multicenter trials.
authors: Iu N
authors: IuN
authors: Belenkov
authors: E V
authors: EV
authors: Privalova
authors: V Iu
authors: VIu
authors: Kaplunova
authors: N V
authors: NV
authors: Khabarova
authors: G A
authors: GA
authors: Shakar'iants
mesh_terms: D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D003937:Diagnosis, Differential; D003935:Diagnostic Techniques, Cardiovascular; D020022:Genetic Predisposition to Disease; D014943:Global Health; D006801:Humans; D009017:Morbidity; D012307:Risk Factors; D009626:Terminology as Topic