title: Reported changes in sexual behaviour and human papillomavirus knowledge in Peruvian female sex workers following participation in a human papillomavirus vaccine trial.
abstract: Limited data exist on the effect of clinical trial participation on sexual behavioural change. Two hundred female sex workers working in Lima, Peru received human papillomavirus (HPV) vaccine in either the standard (0, 2, 6 months) or modified (0, 3, 6 months) schedule. Participants received comprehensive screening and treatment for sexually transmitted infections (STIs), counselling on safe sex practices, education about HPV and the HPV vaccine, contraceptives (oral and condoms) and family planning at each visit. We assessed vaccine completion rates, change in sexual practices, and changes in HPV knowledge before and after participation in the vaccine trial. There were high rates of vaccine completion, 91% overall. The estimated number of reported new and total clients over a 30-day period decreased significantly (P < 0.001). Knowledge about HPV and HPV-related disease increased among all participants. In addition, all participants listed at least one preventive strategy during the month 7 follow-up survey.
authors: Program in Public Health, Department of Population Health & Disease Prevention, University of California, Anteater Instruction and Research Building #2024, Irvine, CA 92697, USA. brandojb@uci.edu
authors: B
authors: B
authors: Brown
authors: M M
authors: MM
authors: Blas
authors: O
authors: O
authors: Heidari
authors: C
authors: C
authors: Carcamo
authors: N A
authors: NA
authors: Halsey
mesh_terms: D000293:Adolescent; D000328:Adult; D017280:Condoms / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000517:prevention & control; D007722:Health Knowledge, Attitudes, Practice; D006630:Hispanic or Latino / Q000523:psychology / Q000706:statistics & numerical data; D006801:Humans; D030361:Papillomavirus Infections / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000008:administration & dosage*; D010568:Peru; D040242:Risk Reduction Behavior; D021841:Safe Sex / Q000523:psychology / Q000706:statistics & numerical data; D060386:Sex Workers; D012725:Sexual Behavior / Q000523:psychology* / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D053918:Papillomavirus Vaccines
keywords: HIV; HPV vaccine; Peruvian female sex workers; human papillomavirus; prevention; sexual risk behaviour; sexually transmitted infections