title: Less invasive palliative surgery for spinal metastases.
abstract: BACKGROUND
  There may be patients with spinal metastasis for whom neither vertebroplasty/kyphoplasty nor open surgery is appropriate. Percutaneous pedicle screw fixation (PPSF) may fill the gap between techniques.
  
  
  OBJECTIVE
  To assess the outcome of the PPSF and radiotherapy/chemotherapy.
  
  
  METHODS
  PPSF was performed for 16 patients (mean age, 57  ± 12 years) with pathologic fractures, Tomita score ≥ 5, 3-6 months of life expectancy, minimal epidural tumor extension and a Nurick grade better than 3. PPSF was performed under general anesthesia. Collapsed vertebra(e) was restored during assembly of contoured rod. Vertebroplasty was then performed for 14 patients at the restored vertebra(e). The Eastern Cooperative Oncology Group (ECOG) performance status grade was 2 in seven patients and 3 in nine. The numerical rating pain score (NRS) was 8.2  ± 1.8. The follow-up was 261 ± 193 days.
  
  
  RESULTS
  All patients walked home at postoperative day 4-7. Radiotherapy and chemotherapy was performed for 8 and 10 patients, respectively. ECOG was improved or stationary in 13/16 (81%) at 1-month and improved in 6/6 of alive patients at the last follow-up. NRS was 3.8 ± 2.0. The median ambulation and survival times were 207 and 222 days.
  
  
  CONCLUSIONS
  Using a multidisciplinary approach, quality of life can be improved for fragile patients with spinal metastasis.
authors: Department of Neurosurgery, Seoul National University Hospital and College of Medicine, Seoul, South Korea; Neuroscience Research Institute, Seoul National University Medical Research Center, Seoul, South Korea; Clinical Research Institute, Seoul National University Hospital, Seoul, South Korea.
authors: Chi Heon
authors: CH
authors: Kim
authors: Chun Kee
authors: CK
authors: Chung
authors: Seil
authors: S
authors: Sohn
authors: Sungjoon
authors: S
authors: Lee
authors: Sung Bae
authors: SB
authors: Park
mesh_terms: D001863:Bone Screws; D059186:Chemoradiotherapy, Adjuvant; D005260:Female; D006801:Humans; D016268:Internal Fixators; D008297:Male; D008875:Middle Aged; D013125:Spinal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery*; D016896:Treatment Outcome
keywords: Tomita; instrumentation; less invasive; neoplasm metastasis; palliative; spine