title: Prevalence and factors associated with erectile dysfunction in a cohort of HIV-infected patients.
abstract: To determine the prevalence of erectile dysfunction and its associated factors we conducted an observational study on a consecutive cohort of asymptomatic HIV-positive men. All the patients completed a questionnaire to evaluate erectile dysfunction based on the International Index of Erectile Function, a validated survey for the diagnosis of anxiety and depression (self-administered HAD), and a questionnaire about cardiovascular risk factors. Epidemiological, clinical, and analytical data were collected. In all, 158 men, participated: mean age 46.0 years, 96.2% on antiretroviral therapy (91.3% undetectable viral load), and the mean CD4 count was 534 cells/mL. Erectile dysfunction was present in 106 (67.1%) patients, and associated factors were age (OR 4.5 for each 5 years; 95% CI 4.3-4.7; p=0.0001) and anxiety (OR 8.2, 95% CI 2.2-30.4; p=0.002). The prevalence of erectile dysfunction is high in men living with HIV, even in those with good immunovirological control. It is related to increasing age and anxiety, both of which are important factors within our HIV cohort.
authors: Unidad de Gestión Clínica de Medicina Interna, Hospital Universitario Virgen de la Victoria, Málaga, Spain.
authors: I
authors: I
authors: Pérez
authors: T
authors: T
authors: Moreno
authors: F
authors: F
authors: Navarro
authors: J
authors: J
authors: Santos
authors: R
authors: R
authors: Palacios
mesh_terms: D000328:Adult; D000367:Age Factors; D019380:Anti-HIV Agents / Q000009:adverse effects / Q000627:therapeutic use; D001008:Anxiety Disorders / Q000150:complications / Q000453:epidemiology; D018791:CD4 Lymphocyte Count; D002318:Cardiovascular Diseases / Q000150:complications / Q000453:epidemiology; D015331:Cohort Studies; D003863:Depression / Q000150:complications / Q000453:epidemiology; D007172:Erectile Dysfunction / Q000150:complications / Q000453:epidemiology* / Q000209:etiology*; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D007006:Hypogonadism / Q000150:complications / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D012959:Socioeconomic Factors; D013030:Spain / Q000453:epidemiology; D011795:Surveys and Questionnaires; D019562:Viral Load
chemical_list: D019380:Anti-HIV Agents
keywords: AIDS; HIV; anxiety disorder; cardiovascular risk; endocrine disorder; erectile dysfunction; men; prevalence