title: Single-chain polymer self-assembly using complementary hydrogen bonding units.
abstract: A triblock copolymer containing the complementary hydrogen bonding recognition pair ureidoguanosine-diaminonaphthyridine (UG-DAN) as pendant functional groups is synthesized using ring-opening metathesis polymerization (ROMP). The norbornene-based DAN monomer is shown to allow for a controlled polymerization when polymerized in the presence of a modified-UG molecule that serves as a protecting group, subsequently allowing for the fabrication of functionalized triblock copolymers. The self-assembly of the copolymers was characterized using dynamic light scattering and (1) H NMR spectroscopy. It is demonstrated that the polymers self-assemble via complementary hydrogen bonding motifs even at low dilutions, indicating intramolecular interactions.
authors: Department of Chemistry and Molecular Design Institute, New York University, New York, NY, 10003, USA.
authors: Joy
authors: J
authors: Romulus
authors: Marcus
authors: M
authors: Weck
mesh_terms: D006151:Guanosine / Q000737:chemistry; D006860:Hydrogen Bonding; D008027:Light; D009682:Magnetic Resonance Spectroscopy; D009287:Naphthyridines / Q000737:chemistry; D009636:Norbornanes / Q000737:chemistry; D058105:Polymerization; D011108:Polymers / Q000737:chemistry*; D012542:Scattering, Radiation
chemical_list: D009287:Naphthyridines; D009636:Norbornanes; D011108:Polymers; D006151:Guanosine
keywords: ROMP; hydrogen bonding; intramolecular folding; self-assembly