title: Central fever due to hypothalamic lesion in a patient with tuberculous meningitis.
abstract: Abnormalities of body temperature are perhaps the most common features in many systemic pathologic processes. Such pathologic alterations are nearly always the result of extrinsic factors (for example, systemic pyrogens) which affect the hypothalamic thermoregulatory center by way of circulatory system. Much less common is alterations in temperature regulation resulting from intrinsic lesions of the thermoregulatory center in the hypothalamus. We report a patient with tuberculous meningitis who continued to have persistent fever despite the satisfactory treatment of her tuberculosis. A central thermoregulatory defect was documented and was attributed to a small structural lesion in the anterior hypothalamus.
authors: Department of Neurosciences, King Faisal Specialist Hospital and Research Centre, MBC J76, PO Box 40047, Jeddah 21499, Kingdom of Saudi Arabia. Tel. +966 (2) 6677777 Ext. 5819 Fax. +966 (2) 6677777 Ext. 5813. E-mail: amalshahrani@hotmail.com.
authors: Abdulrahman M
authors: AM
authors: Alshahrani
authors: Yousef A
authors: YA
authors: Al-Said
authors: Irfan A
authors: IA
authors: Mamoun
authors: Leopold J
authors: LJ
authors: Streletz