title: WholeCellViz: data visualization for whole-cell models.
abstract: BACKGROUND
  Whole-cell models promise to accelerate biomedical science and engineering. However, discovering new biology from whole-cell models and other high-throughput technologies requires novel tools for exploring and analyzing complex, high-dimensional data.
  
  
  RESULTS
  We developed WholeCellViz, a web-based software program for visually exploring and analyzing whole-cell simulations. WholeCellViz provides 14 animated visualizations, including metabolic and chromosome maps. These visualizations help researchers analyze model predictions by displaying predictions in their biological context. Furthermore, WholeCellViz enables researchers to compare predictions within and across simulations by allowing users to simultaneously display multiple visualizations.
  
  
  CONCLUSIONS
  WholeCellViz was designed to facilitate exploration, analysis, and communication of whole-cell model data. Taken together, WholeCellViz helps researchers use whole-cell model simulations to drive advances in biology and bioengineering.
authors: Department of Bioengineering, Stanford University, Stanford, CA 94025, USA. mcovert@stanford.edu.
authors: Ruby
authors: R
authors: Lee
authors: Jonathan R
authors: JR
authors: Karr
authors: Markus W
authors: MW
authors: Covert
mesh_terms: D002453:Cell Cycle / Q000235:genetics; D002874:Chromosome Mapping; D019295:Computational Biology / Q000379:methods*; D003198:Computer Simulation; D016208:Databases, Factual; D030541:Databases, Genetic; D020407:Internet; D008954:Models, Biological; D012984:Software
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