title: Synthesis of strongly green-photoluminescent graphene quantum dots for drug carrier.
abstract: A novel approach has been developed for the preparation of strongly green-photoluminescent graphene quantum dots (GQDs-PEG) which have been surface-passivated by polyethylene glycol. The photoluminescence (PL) quantum yield of the GQDs-PEG with 400 nm excitation was about 18.8%, which was higher than other GQDs reported in the literature. More importantly, the surface-passivated PEG on GQDs can not only enhance PL intensity but also load drug by hydrogen bonding. Moreover, the high specific surface area of GQDs-PEG endowed them high loading capability (2.5 mg/mg) to carry drug. The results demonstrated that the GQDs-PEG were suitable for drug carrier and cell imaging.
authors: Laboratory of Fiber Materials and Modern Textiles, The Growing Base for State Key Laboratory, College of Chemical and Environment Engineering, Shandong Sino-Japanese, Center for Collaborative Research of Carbon Nanomaterials, CollaborativeInnovation Center for Marine Biomass Fiber Materials and Textiles, Qingdao University, Shandong 266071, PR China. Electronic address: wangzonghua@qdu.edu.cn.
authors: Zonghua
authors: Z
authors: Wang
authors: Jianfei
authors: J
authors: Xia
authors: Chengfeng
authors: C
authors: Zhou
authors: Brian
authors: B
authors: Via
authors: Yanzhi
authors: Y
authors: Xia
authors: Feifei
authors: F
authors: Zhang
authors: Yanhui
authors: Y
authors: Li
authors: Linhua
authors: L
authors: Xia
authors: Jie
authors: J
authors: Tang
mesh_terms: D058948:Cell Tracking / Q000379:methods; D004317:Doxorubicin / Q000008:administration & dosage; D004337:Drug Carriers / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D049449:Luminescence; D046529:Microscopy, Electron, Transmission; D011092:Polyethylene Glycols / Q000737:chemistry; D045663:Quantum Dots / Q000737:chemistry* / Q000648:ultrastructure; D013050:Spectrometry, Fluorescence; D013053:Spectrophotometry; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D004337:Drug Carriers; D011092:Polyethylene Glycols; D006108:Graphite; D004317:Doxorubicin
keywords: Drug carrier; Graphene quantum dots; Photoluminescence; Polyethylene glycol; Surface passivation