title: Investigation of the risk factors for leukoaraiosis (LA).
abstract: Leukoaraiosis (LA) describes abnormal changes in the cerebral white matter frequently seen on CT and MRI in older adults. Its appearance indicates mild brain injury, and it is often regarded as a mark of senile dementia. Through the analysis of related risk factors of 6000 patients with LA diagnosed by cranial MRI in our department, we found that age, cerebral infarction, lacunar infarction, history of brain hemorrhage, and increased triglycerides were risk factors for LA, and the relative risk odds ratio values were 2.135 (95% confidence interval [CI] = 1.874-2.501), 3.330 (95% CI = 1.922-3.997), 3.412 (95% CI = 2.986-3.512), 3.611 (95% CI = 2.054-9.147), and 1.457 (95% CI = 1.058-1.769), respectively. Through the identification of the risk factors for LA and effective interventions, the occurrence of dementia, stroke, and premature death may be effectively prevented.
authors: People's Hospital of Zhengzhou, Zhengzhou, Henan Province, China. 13703923296@163.com
authors: Sijia
authors: S
authors: Zhang
authors: Xia
authors: X
authors: Kang
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001921:Brain / Q000473:pathology*; D002544:Cerebral Infarction / Q000453:epidemiology; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000453:epidemiology; D049292:Leukoaraiosis / Q000175:diagnosis* / Q000453:epidemiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D059409:Stroke, Lacunar / Q000453:epidemiology; D014280:Triglycerides / Q000097:blood; D055815:Young Adult
chemical_list: D014280:Triglycerides
keywords: investigation; leukoaraiosis (LA); magnetic resonance imaging (MRI) examination; regression analysis; risk factors