title: Cloud prediction of protein structure and function with PredictProtein for Debian.
abstract: We report the release of PredictProtein for the Debian operating system and derivatives, such as Ubuntu, Bio-Linux, and Cloud BioLinux. The PredictProtein suite is available as a standard set of open source Debian packages. The release covers the most popular prediction methods from the Rost Lab, including methods for the prediction of secondary structure and solvent accessibility (profphd), nuclear localization signals (predictnls), and intrinsically disordered regions (norsnet). We also present two case studies that successfully utilize PredictProtein packages for high performance computing in the cloud: the first analyzes protein disorder for whole organisms, and the second analyzes the effect of all possible single sequence variants in protein coding regions of the human genome.
authors: TUM, Department of Informatics, Bioinformatics & Computational Biology-I12, Garching, Germany. lkajan@rostlab.org
authors: László
authors: L
authors: Kaján
authors: Guy
authors: G
authors: Yachdav
authors: Esmeralda
authors: E
authors: Vicedo
authors: Martin
authors: M
authors: Steinegger
authors: Milot
authors: M
authors: Mirdita
authors: Christof
authors: C
authors: Angermüller
authors: Ariane
authors: A
authors: Böhm
authors: Simon
authors: S
authors: Domke
authors: Julia
authors: J
authors: Ertl
authors: Christian
authors: C
authors: Mertes
authors: Eva
authors: E
authors: Reisinger
authors: Cedric
authors: C
authors: Staniewski
authors: Burkhard
authors: B
authors: Rost
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D003198:Computer Simulation; D057225:Data Mining / Q000379:methods; D030562:Databases, Protein; D020407:Internet; D008956:Models, Chemical; D008957:Models, Genetic; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011381:Programming Languages; D011506:Proteins / Q000737:chemistry / Q000235:genetics / Q000648:ultrastructure; D020539:Sequence Analysis, Protein / Q000379:methods; D012984:Software; D013329:Structure-Activity Relationship
chemical_list: D011506:Proteins
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