title: Determination of diosmin in pharmaceutical formulations using Fourier transform infrared spectrophotometry.
abstract: A Fourier transform infrared (FT-IR) spectrometric method was developed for the rapid, direct measurement of diosmin in different pharmaceutical drugs. Conventional KBr-spectra were compared for best determination of active substance in commercial preparations. The Beer-Lambert law and two chemometric approaches, partial least squares (PLS) and principal component regression (PCR+) methods, were tried in data processing.
authors: Cromatec_plus srl, Analytical Research Department, 18 Sos. Cotroceni, Bucharest 6, 060114, Romania.
authors: Andrei A
authors: AA
authors: Bunaciu
authors: Gabriela Elena
authors: GE
authors: Udristioiu
authors: Lavinia L
authors: LL
authors: Ruţă
authors: Serban
authors: S
authors: Fleschin
authors: Hassan Y
authors: HY
authors: Aboul-Enein
keywords: Chemometric methods; Diosmin; Drug analysis; FT-IR analysis
references: J Pharm Sci. 1969 Aug;58(8):911-29
references: 4899118
references: Angiology. 1994 Jun;45(6):419-28
references: 8203767