title: Guillain-Barre syndrome. Pattern of muscle weakness.
abstract: OBJECTIVE
  The objective of this study was to determine the pattern of muscle weakness in patients with Guillain-Barre Syndrome.
  
  
  METHODS
  In a cross-sectional study, 50 Iraqi patients aged one to 60 years diagnosed with Guillain-Barre Syndrome according to Asbury criteria, admitted in 5 Neurological Centers in Baghdad, Iraq between October 1997 and October 1999, were studied for pattern of muscle weakness by clinical evaluation of power using scale from 0-5.
  
  
  RESULTS
  In 80% of patients, muscle weakness started in lower limbs while at presentation 4 limb weakness was the most frequent (96%). It was found that the upper extremity weakness was mainly distal in 73% of patients, while lower extremity weakness was mainly proximal in 68%. Weakness in extremities associated with cranial nerve involvement occurred in 72% of patients. Trunk muscles were involved in 34%. Various modes of spread of muscle weakness were seen in this study but the ascending variety was the most common occurring in 78% of patients and it was characterized by upward spread, however, contiguous parts of the body were not always successively involved.
  
  
  CONCLUSIONS
  Upper extremity weakness was mainly distal while lower extremity weakness was mainly proximal and there is predilection for trunk muscle involvement that is quite unusual in other types of polyneuropathy. Therefore, all patients with suspected Guillain-Barre Syndrome should be examined carefully for pattern of muscle weakness in extremities, which may be helpful in differential diagnosis especially in early stages of the disease.
authors: Department of Neurology, Hammad-Shihab Military Teaching Hospital, PO Box 19164, Althobad, Baghdad, Iraq.
authors: Mohamed A
authors: MA
authors: Alzaidi
authors: Kasid A
authors: KA
authors: Nouri