title: Introduction to the immune system.
abstract: The immune system in a broad sense is a mechanism that allows a living organism to discriminate between "self" and "non-self." Examples of immune systems occur in multicellular organisms as simple and ancient as sea sponges. In fact, complex multicellular life would be impossible without the ability to exclude external life from the internal environment. This introduction to the immune system explores the cell types and soluble factors involved in immune reactions, as well as their location in the body during development and maintenance. Additionally, a description of the immunological events during an innate and adaptive immune reaction to an infection is discussed, as well as a brief introduction to autoimmunity and cancer immunity.
authors: Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, ON, Canada.
authors: Scott
authors: S
authors: McComb
authors: Aude
authors: A
authors: Thiriot
authors: Lakshmi
authors: L
authors: Krishnan
authors: Felicity
authors: F
authors: Stark
mesh_terms: D056704:Adaptive Immunity / Q000502:physiology; D000818:Animals; D015551:Autoimmunity / Q000502:physiology*; D006801:Humans; D007107:Immune System / Q000378:metabolism*; D007113:Immunity, Innate / Q000502:physiology