title: Calcium signaling: septins organize the SOC channel.
abstract: Store-operated Ca(2+) entry is a widely encountered mechanism for generating cytoplasmic Ca(2+) signals. From a whole-genome screen in HeLa cells, a new study reveals that cytoskeletal septins play a critical role in this process, by organizing signaling structures in the plasma membrane.
authors: Laboratory of Signal Transduction, National Institute of Environmental Health Sciences - NIH, Department of Health and Human Services, Research Triangle Park, NC 27709, USA. putney@niehs.nih.gov
authors: James W
authors: JW
authors: Putney
mesh_terms: D002118:Calcium / Q000378:metabolism*; D006801:Humans; D050778:NFATC Transcription Factors / Q000378:metabolism*; D034622:RNA Interference; D034741:RNA, Small Interfering / Q000235:genetics*; D058112:Septins / Q000378:metabolism*
chemical_list: D050778:NFATC Transcription Factors; D034741:RNA, Small Interfering; D058112:Septins; D002118:Calcium