title: Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China.
abstract: We collected data on feasibility and acceptability of a real-time web-linked adherence monitoring container among HIV-positive injection drug users (IDU) in China. "Wisepill" uses wireless technology to track on-time medication dosing. Ten patients on antiretroviral therapy (ART) at the Guangxi CDC HIV clinic in Nanning, China, used Wisepill for one ART medication for one month. We monitored device use and adherence and explored acceptability of the device among patients. Mean adherence was 89.2% (SD 10.6%). Half of the subjects reported a positive overall experience with Wisepill. Seven said that it was inconvenient, supported by comments that it was large and conspicuous. Five worried about disclosure of HIV status due to the device; no disclosures were reported. Twelve signal lapses occurred (5.4% of prescribed doses), of which one was due to technical reasons, nine to behavioral reasons (both intentional and unintentional), and two to unclear reasons. Although the technical components must be monitored carefully, and acceptability to patients presents challenges which warrant further exploration, the Wisepill device has potential for adherence interventions that deliver rapid adherence-support behavioral feedback directly to patients, including IDU. The use of wireless technology appears uniquely promising for providing time-sensitive communication on patient behavior that can be harnessed to maximize the benefits of HIV treatment.
authors: Center for Global Health and Development, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown, 3rd Floor, Boston, MA 02118, USA.
authors: Mary
authors: M
authors: Bachman Desilva
authors: Allen L
authors: AL
authors: Gifford
authors: Xu
authors: X
authors: Keyi
authors: Zhong
authors: Z
authors: Li
authors: Cheng
authors: C
authors: Feng
authors: Mohamad
authors: M
authors: Brooks
authors: Mark
authors: M
authors: Harrold
authors: Hu
authors: H
authors: Yueying
authors: Christopher J
authors: CJ
authors: Gill
authors: Xie
authors: X
authors: Wubin
authors: Taryn
authors: T
authors: Vian
authors: Jessica
authors: J
authors: Haberer
authors: David
authors: D
authors: Bangsberg
authors: Lora
authors: L
authors: Sabin
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