title: Epidermal nevus and ameloblastoma: a rare association.
abstract: Epidermal nevi are clinical manifestations of a malformation affecting the embryonic ectoderm. They appear as linear verrucous lesions and are more often located in the skin of the trunk or the extremities. Rarely, verrucous lesions affect the oral mucosa. Epidermal nevi can be a component of epidermal nevus syndrome (ENS), which is characterized by malformations involving several organs, such as the central nervous system. ENS is rarely associated with other solid tumors. We present the case of a patient affected by ENS who developed maxillary and mandibular ameloblastomas. Epidermal nevi were located in the left middle and lower third of the face and in the left cervical region, whereas the ameloblastomas arose within the left maxillary mucosa and within the left mandibular ramus. Features of the syndrome are described and the relevant literature is reviewed.
authors: Assistant Professor, Department of Maxillofacial Surgery, University of Milan, San Paolo Hospital, Milan, Italy. Electronic address: giacomo.colletti@gmail.com.
authors: Giacomo
authors: G
authors: Colletti
authors: Assistant Professor, Department of Maxillofacial Surgery, University of Milan, San Paolo Hospital, Milan, Italy.
authors: Fabiana
authors: F
authors: Allevi
authors: Assistant Professor, Division of Pathology, Department of Health Sciences, University of Milan, San Paolo Hospital, Milan, Italy.
authors: Laura
authors: L
authors: Moneghini
authors: Assistant Professor, Department of Maxillofacial Surgery, University of Milan, San Paolo Hospital, Milan, Italy.
authors: Dimitri
authors: D
authors: Rabbiosi
authors: Associate Professor, Department of Oral and Maxillofacial Surgery, University of Verona, Italy.
authors: Dario
authors: D
authors: Bertossi
authors: Private practice, Turin, Italy.
authors: Iliuska
authors: I
authors: Frau
authors: Associate Professor, Department of Maxillofacial Surgery, University of Milan, San Paolo Hospital, Milan, Italy.
authors: Federico
authors: F
authors: Biglioli
authors: Consultant Professor, Centro Malattie Cutanee Ereditarie, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano and Pediatric Clinic 1, Milan, Italy.
authors: Gianluca
authors: G
authors: Tadini
mesh_terms: D000564:Ameloblastoma / Q000151:congenital* / Q000000981:diagnostic imaging / Q000601:surgery; D002648:Child; D005260:Female; D006801:Humans; D008339:Mandibular Neoplasms / Q000151:congenital* / Q000000981:diagnostic imaging / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D020752:Neurocutaneous Syndromes / Q000151:congenital* / Q000601:surgery; D009506:Nevus / Q000151:congenital* / Q000601:surgery; D035583:Rare Diseases / Q000151:congenital* / Q000000981:diagnostic imaging / Q000601:surgery; D014057:Tomography, X-Ray Computed