title: Engineering NLR immune receptors for broad-spectrum disease resistance.
abstract: Two recent reports by Maekawa et al. and Narusaka et al. demonstrated the transfer of a nucleotide-binding domain and leucine-rich repeat (NLR) family of immune receptors into evolutionarily diverged plants without causing adverse fitness consequences. The applications of NLRs in engineering durable and broad-spectrum resistance in plants are highlighted here.
authors: Department of Biology, University of Alabama at Birmingham, AL 35294-1170, USA. smukhtar@uab.edu
authors: M Shahid
authors: MS
authors: Mukhtar
mesh_terms: D018556:Crops, Agricultural / Q000235:genetics / Q000276:immunology / Q000592:standards; D060467:Disease Resistance / Q000502:physiology*; D007930:Leucine; D009711:Nucleotides / Q000378:metabolism; D010940:Plant Proteins / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D010944:Plants / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D030821:Plants, Genetically Modified; D015202:Protein Engineering; D017434:Protein Structure, Tertiary; D011971:Receptors, Immunologic / Q000235:genetics*; D020449:Repetitive Sequences, Amino Acid; D019076:Transgenes
chemical_list: D009711:Nucleotides; D010940:Plant Proteins; D011971:Receptors, Immunologic; D007930:Leucine