title: D-Penicillamine induced myasthenia gravis.
abstract: Myasthenia gravis is a disorder of impaired neuromuscular transmission resulting in weakness and abnormal fatigability on exertion, improved by anti-acetyl cholinesterase drugs. A number of drugs are known to exacerbate myasthenia gravis or interfere with neuromuscular transmission. We report a case of D-penicillamine induced myasthenia gravis who developed ptosis, diplopia and easy fatigability, 4 years after initiation of the drug for Wilson`s disease. On stopping the drug, within 3 months all her symptoms disappeared without any anti-acetyl cholinesterase drugs. Thus, the onset of drug induced myasthenia gravis could be insidious but the withdrawal of the drug leads to rapid recovery.
authors: Department of Child Health, The Royal Hospital, PO Box 1331, P.C. 111, Seeb CPO, Sultanate of Oman. Tel. +968 593667. Fax. +968 699869. E-mail: tomas@omantel.net.om.
authors: Thomas
authors: T
authors: Varghese
authors: Riaz
authors: R
authors: Ahmed
authors: Jayaram D
authors: JD
authors: Sankaran
authors: Saleh M
authors: SM
authors: Al-Khusaiby