title: Selectively N-methylated soluble IAPP mimics as potent IAPP receptor agonists and nanomolar inhibitors of cytotoxic self-assembly of both IAPP and Aβ40.
authors: Division of Peptide Biochemistry, Technische Universität München, Emil-Erlenmeyer-Forum 5, 85354 Freising (Germany) http://pbch.wzw.tum.de/
authors: Li-Mei
authors: LM
authors: Yan
authors: Aleksandra
authors: A
authors: Velkova
authors: Marianna
authors: M
authors: Tatarek-Nossol
authors: Gerhard
authors: G
authors: Rammes
authors: Andrei
authors: A
authors: Sibaev
authors: Erika
authors: E
authors: Andreetto
authors: Michael
authors: M
authors: Kracklauer
authors: Maria
authors: M
authors: Bakou
authors: Eleni
authors: E
authors: Malideli
authors: Burkhard
authors: B
authors: Göke
authors: Jörg
authors: J
authors: Schirra
authors: Martin
authors: M
authors: Storr
authors: Aphrodite
authors: A
authors: Kapurniotu
mesh_terms: D000595:Amino Acid Sequence; D065091:Amylin Receptor Agonists; D000682:Amyloid / Q000037:antagonists & inhibitors* / Q000378:metabolism / Q000648:ultrastructure; D016229:Amyloid beta-Peptides / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D058228:Islet Amyloid Polypeptide / Q000737:chemistry* / Q000378:metabolism / Q000648:ultrastructure; D008745:Methylation; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000648:ultrastructure; D057786:Peptidomimetics / Q000737:chemistry* / Q000494:pharmacology*; D058287:Receptors, Islet Amyloid Polypeptide / Q000378:metabolism
chemical_list: D065091:Amylin Receptor Agonists; D000682:Amyloid; D016229:Amyloid beta-Peptides; D058228:Islet Amyloid Polypeptide; D010446:Peptide Fragments; D057786:Peptidomimetics; D058287:Receptors, Islet Amyloid Polypeptide; C538897:amyloid beta-protein (40-42)
keywords: IAPP receptor agonist; islet amyloid polypeptide; protein interactions; self-assembly; β-amyloid peptide