title: Functional pituitary tumors masquerading as primary glaucoma and effect of hypophysectomy on intraocular tension.
abstract: We report 2 bilateral cases that presented as primary ocular hypertension and primary angle-closure glaucoma, respectively; however, they were subsequently discovered to be harboring secretory pituitary tumors. After transsphenoidal tumor resection, intraocular pressures (IOPs) in all 4 eyes returned to normal levels. Sudden rise in IOP then again served as a primary manifestation of relapse in the second patient with growth hormone secreting pituitary tumor. It was not found feasible for resurgery; thus, patient needed trabeculectomy in both eyes to achieve an optimum control of intraocular tension. We conclude that pituitary adenomas may mimic primary glaucoma without producing vertical hemianopia and cause a reversible rise in IOP. Furthermore, a careful ongoing expert ophthalmologic assessment may serve as a useful clinical marker for early relapse in these tumors.
authors: Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
authors: Shikha
authors: S
authors: Gupta
authors: Ramanjit
authors: R
authors: Sihota
authors: Viney
authors: V
authors: Gupta
authors: Tanuj
authors: T
authors: Dada
authors: Varun
authors: V
authors: Gogia
authors: Ajay
authors: A
authors: Sharma
mesh_terms: D049913:ACTH-Secreting Pituitary Adenoma / Q000175:diagnosis* / Q000601:surgery; D000236:Adenoma / Q000175:diagnosis* / Q000601:surgery; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007016:Hypophysectomy; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis* / Q000601:surgery; D014130:Trabeculectomy; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology