title: Malignant mesothelioma: development to therapy.
abstract: Malignant mesothelioma (MM) is an aggressive cancer of the mesothelium caused by asbestos. Asbestos use has been reduced but not completely stopped. In addition, natural or man-made disasters will continue to dislodge asbestos from old buildings into the atmosphere and as long as respirable asbestos is available, MM will continue to be a threat. Due to the long latency period of MM development, it would still take decades to eradicate this disease if asbestos was completely removed from our lives today. Therefore, there is a need for researchers and clinicians to work together to understand this deadly disease and find a solution for early diagnosis and treatment. This article focuses on developmental mechanisms as well as current therapies available for MM.
authors: Pathology Department, University of Vermont, College of Medicine, Burlington, Vermont.
authors: Joyce K
authors: JK
authors: Thompson
authors: Catherine M
authors: CM
authors: Westbom
authors: Arti
authors: A
authors: Shukla
mesh_terms: D001194:Asbestos / Q000633:toxicity*; D006801:Humans; D008175:Lung Neoplasms / Q000139:chemically induced / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology / Q000628:therapy*; D008654:Mesothelioma / Q000139:chemically induced / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology / Q000628:therapy*; D000086002:Mesothelioma, Malignant; D058990:Molecular Targeted Therapy
chemical_list: D001194:Asbestos
keywords: ASBESTOS; INFLAMMATION; MALIGNANT MESOTHELIOMA; MESOTHELIUM
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