title: Spectroscopic studies of micelle-enhanced ligand exchange of gallium (III)/4-(2-pyridylazo) resorcinol complex by calf thymus DNA.
abstract: The effect of cationic micelles of cetyltrimethylammonium bromide (CTAB) on the interaction of gallium (III) with 4-(2-pyridylazo) resorcinol (PAR) under varying conditions has been studied spectrophotometrically. At pH 6.0, CTAB (0.05% w/v) markedly enhanced the absorption intensity of gallium (III)-PAR complex. Furthermore, the introduction of CTAB provided unique selectivity for the ligand exchange of Ga(III)-PAR by calf thymus dsDNA over calf thymus ssDNA. This phenomenon offers a novel spectrophotometric sensing strategy for direct detection of dsDNA.
authors: Department of Chemistry, North Carolina Central University, Durham, NC 27707, USA.
authors: Jennifer M
authors: JM
authors: Romeika
authors: Charina L
authors: CL
authors: Spurgeon
authors: Fei
authors: F
authors: Yan
mesh_terms: D000818:Animals; D002417:Cattle; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry / Q000378:metabolism; D056831:Coordination Complexes / Q000737:chemistry* / Q000378:metabolism; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D005708:Gallium / Q000737:chemistry* / Q000378:metabolism; D008024:Ligands; D008099:Liver / Q000378:metabolism; D008823:Micelles; D015394:Molecular Structure; D012118:Resorcinols / Q000737:chemistry* / Q000378:metabolism; D013056:Spectrophotometry, Ultraviolet; D013501:Surface-Active Agents / Q000737:chemistry / Q000378:metabolism
chemical_list: D002593:Cetrimonium Compounds; D056831:Coordination Complexes; D008024:Ligands; D008823:Micelles; D012118:Resorcinols; D013501:Surface-Active Agents; D004247:DNA; C427203:calf thymus DNA; D005708:Gallium; C028398:4-(2-pyridylazo)resorcinol; D000077286:Cetrimonium
keywords: CTAB; Gallium; Micelle; PAR; dsDNA; ssDNA