title: Anesthetic implications of emergent Cesarean section in a parturient with Noonan syndrome and bacterial endocarditis.
abstract: Noonan syndrome is a relatively common genetically transmitted disorder characterized by facial, cardiac, and musculoskeletal abnormalities. The management of a 27 year old woman with Noonan syndrome at 23 weeks' gestation, presenting with premature labor, who required an emergent Cesarean section for placental abruption, is discussed. In addition to Noonan syndrome, this patient had bacterial endocarditis involving the mitral and aortic valves. The anesthetic implications of Noonan syndrome and endocarditis during pregnancy are presented.
authors: Anesthesiologists of Greater Orlando, Orlando, FL 32803, USA.
authors: Charles J
authors: CJ
authors: Chase
authors: Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA; Anesthesiology Service, Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI 53295, USA.
authors: Elena J
authors: EJ
authors: Holak
authors: Anesthesiology Service, Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI 53295, USA. Electronic address: pspagel@mcw.edu.
authors: Paul S
authors: PS
authors: Pagel
mesh_terms: D000037:Abruptio Placentae; D000328:Adult; D000773:Anesthesia, Obstetrical / Q000379:methods; D001021:Aortic Valve / Q000382:microbiology; D002585:Cesarean Section / Q000379:methods*; D004697:Endocarditis, Bacterial / Q000382:microbiology*; D005260:Female; D006801:Humans; D008943:Mitral Valve / Q000382:microbiology; D009634:Noonan Syndrome / Q000503:physiopathology*; D007752:Obstetric Labor, Premature; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011251:Pregnancy Complications, Infectious / Q000382:microbiology
keywords: Anesthesia, obstetrical; Cardiomyopathy, hypertrophic; Cesarean section; Endocarditis; Noonan syndrome; Placental abruption