title: Effects of weight on blood pressure at rest and during exercise.
abstract: Body weight (BW) and blood pressure (BP) have a close relationship, which has been accounted for by hormonal changes. No previous study has evaluated the effect of wearing an external weight vest on BP to determine whether there is a simple mechanism between BW and BP. Seventeen healthy volunteers underwent weight reduction (WR) through caloric restriction. Before and after WR, BW, body fat percentage and BP at rest and during exercise were measured. Before and after WR, exercise testing was performed twice with the random allocation of a weight vest (10 kg) during one of the tests. Linear regression was used to detect independent associations between BP and the weight vest, BW and body fat percentage. BW decreased from 89.4 ± 15.4 kg to 79.1 ± 14.0 kg following WR (P<0.001). WR led to significant decreases in BP at rest (from 130.0/85.9 mm Hg to 112.5/77.8 mm Hg, P<0.001 for systolic and diastolic BPs) and during exercise. The weight vest significantly increased BP at rest (to 136.1/90.7 mm Hg before and 125.8/84.6 mm Hg after WR) and during exercise. Linear regression analysis identified an independent association between the weight vest and BP (P=0.006 for systolic BP and P=0.009 for diastolic BP at rest). This study demonstrates that wearing an external weight vest has immediate effects on BP at rest and during exercise independent of BW or body fat. More research is needed to understand the physiological mechanisms between weight and BP.
authors: 1] Division of Geriatrics, Department of General Internal Medicine, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland [2] Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland [3] Department of Cardiology and ESH Hypertension Center of Excellence, Luzerner Kantonsspital, Luzern, Switzerland.
authors: Andreas Wolfgang
authors: AW
authors: Schoenenberger
authors: Renate
authors: R
authors: Schoenenberger-Berzins
authors: Paolo Mirco
authors: PM
authors: Suter
authors: Paul
authors: P
authors: Erne
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D001823:Body Composition / Q000502:physiology; D001835:Body Weight / Q000502:physiology*; D002318:Cardiovascular Diseases / Q000150:complications; D018592:Cross-Over Studies; D004038:Diet, Reducing; D004562:Electrocardiography; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D050177:Overweight / Q000503:physiopathology; D012146:Rest; D012307:Risk Factors; D015431:Weight Loss / Q000502:physiology*