title: The use of cell salvage in women undergoing cesarean hysterectomy for abnormal placentation.
abstract: BACKGROUND
  Although transfusion of autologous blood obtained from cell salvage has increased, its role in obstetric practice remains controversial. This case series reports the use of cell salvage in an attempt to avoid allogeneic transfusion in women undergoing cesarean hysterectomy for placenta accreta.
  
  
  METHODS
  This prospective observational study, conducted in a large public maternity hospital, included 41 women with an antenatal diagnosis of placenta accreta, of whom 20 underwent cesarean hysterectomy and 15 received autologous blood after cell salvage. Intraoperative cell salvage was used for autologous blood transfusion, and salvaged blood was monitored for prewash and postfiltration squamous cells, fetal hemoglobin, and potassium concentration. Pre- and postoperative hemoglobin, platelet count and coagulation profile were compared.
  
  
  RESULTS
  Twenty women underwent caesarean hysterectomy. Cell-salvaged blood was collected in 18 women and re infused in 15 women (83.3%). The mean volume of reinfused salvaged blood was 1476 ± 247 mL. Mean potassium concentrations (1.4 ± 1.2 versus 3.7 ± 0.42 mEq/L) and median squamous cell counts (0 [0-1] versus 8 [3-12]/high power field) were significantly lower postfiltration compared to prewash values. There were no instances of intraoperative or postoperative amniotic fluid embolism, hypotension, sepsis or coagulopathy. Of the 15 women who received autologous blood, 13 (86.7%) did not require allogeneic red blood cell transfusion.
  
  
  CONCLUSIONS
  Autologous transfusion of salvaged blood can be used to minimize allogeneic transfusion in women undergoing cesarean hysterectomy for placenta accreta.
authors: Department of Anesthesiology, North West Armed Forces Hospitals, Tabuk, Saudi Arabia; Department of Anesthesiology, North West Armed Forces Hospitals, Tabuk, Saudi Arabia.
authors: A
authors: A
authors: Elagamy
authors: A
authors: A
authors: Abdelaziz
authors: M
authors: M
authors: Ellaithy
mesh_terms: D000328:Adult; D001804:Blood Transfusion, Autologous; D002585:Cesarean Section / Q000379:methods*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D010921:Placenta Accreta / Q000601:surgery*; D011247:Pregnancy; D011446:Prospective Studies
keywords: Abnormal placentation; Cell salvage; Cesarean hysterectomy; Placenta accreta