title: Anti-Inflammatory Effects of Hyptis albida Chloroform Extract on Lipopolysaccharide-Stimulated Peritoneal Macrophages.
abstract: We examined the effects of a chloroform extract of Hyptis albida (CHA) on inflammatory responses in mouse lipopolysaccharide (LPS) induced peritoneal macrophages. Our findings indicate that CHA inhibits LPS-induced production of tumor necrosis factor (TNF- α ) and interleukin-6 (IL-6). During the process, levels of cyclooxygenase-2 (COX-2), nitric oxide synthase (iNOS), and nitric oxide (NO) increased in the mouse peritoneal macrophages; however, the extract suppressed them significantly. These results provide novel insights into the anti-inflammatory actions of CHA and support its potential use in the treatment of inflammatory diseases.
authors: Departamento Sistemas Biológicos, Universidad Autónoma Metropolitana-Xochimilco, Calzada del Hueso 1100, Colonia Villa Quietud, 04960 Mexico, DF, Mexico.
authors: Elizabeth
authors: E
authors: Sánchez Miranda
authors: Julia
authors: J
authors: Pérez Ramos
authors: Cristina
authors: C
authors: Fresán Orozco
authors: Miguel Angel
authors: MA
authors: Zavala Sánchez
authors: Salud
authors: S
authors: Pérez Gutiérrez
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