title: Presentation of suspected pediatric uveitis.
abstract: Presentation of suspected pediatric uveitis: Pediatric uveitis is usually managed in specialized ophthalmic centers in the UK. Meaningful data acquisition in these clinics may be helpful in clinical governance, and healthcare planning in a specialty that is gradually changing due to changes in treatment choices.
  
  
  METHODS
  Retrospective analysis of prospectively acquired data in the Liverpool pediatric uveitis database was performed.
  
  
  RESULTS
  Analysis of our data, based on 147 patients, with a mean age of 10 years, indicated a female to male ratio of 2:1. 99% of patients were Caucasian. Our data indicates 86% of all patients attending the uveitis clinic were diagnosed with juvenile idiopathic arthritis, followed by intermediate uveitis 5% and idiopathic uveitis 4%. 46% of patients required treatment. Systemic treatment included methotrexate (34%), prednisolone (14%), etanercept (6%), ciclosporin (6%), mycophenolate (3%), and infliximab (1%). Severe visual loss (defined by counting fingers or below vision) was seen in 10 eyes despite appropriately treated chronic uveitis.
  
  
  CONCLUSIONS
  Our data shows uveitis-related ocular morbidity in a predominantly pediatric Caucasian population. Patients with severe and chronic uveitis may experience significant uveitis-related complications and subsequent visual loss despite aggressive treatment.
authors: Ophthalmology Department, Royal Liverpool Children's Hospital , Liverpool , UK .
authors: Muhammad Usman
authors: MU
authors: Saeed
authors: Syed Hamid
authors: SH
authors: Raza
authors: Sudeshna
authors: S
authors: Goyal
authors: Gavin
authors: G
authors: Cleary
authors: William David
authors: WD
authors: Newman
authors: Arvind
authors: A
authors: Chandna
mesh_terms: D000293:Adolescent; D000974:Antibodies, Antinuclear / Q000097:blood; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000175:diagnosis* / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D005260:Female; D015796:HLA-B27 Antigen / Q000032:analysis; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D014605:Uveitis / Q000175:diagnosis* / Q000188:drug therapy; D014786:Vision Disorders / Q000175:diagnosis; D014792:Visual Acuity; D055815:Young Adult
chemical_list: D000974:Antibodies, Antinuclear; D018501:Antirheumatic Agents; D015796:HLA-B27 Antigen