title: National observatory on the therapeutic management in ambulatory care patients aged 65 and over, with type 2 diabetes, chronic pain or atrial fibrillation.
abstract: The primary objective of the S.AGES cohort is to describe the real-life therapeutic care of elderly patients. Patients and methods. This is a prospective observational cohort study of 3 700 non-institutionalized patients over the age of 65 years with either type 2 diabetes mellitus (T2DM), chronic pain or atrial fibrillation (AF) recruited by French general practitioners (GPs). Follow-up is planned for 3 years. Baseline characteristics. In the chronic pain sub-cohort, 33% of patients are treated with only grade 1 analgesics, 29% with grade 2 analgesics and 3% with grade 3 analgesics, and 22% have no pain treatment. In the T2DM sub-cohort, 61% of patients have well-controlled diabetes (Hb1c<7%) and 18% are treated with insulin. In the AF sub-cohort, 65% of patients have a CHADS2 score greater than 2, 77% are treated with oral anticoagulants, 17% with platelet inhibitors, 40% with antiarrhythmic drugs and 56% with rate slowing medications. Conclusion. The S.AGES cohort presents a unique opportunity to clarify the real-life therapeutic management of ambulatory elderly subjects and will help to identify the factors associated with the occurrence of major clinical events.
authors: Pharmacology Department Faculty of Medicine Paris-Sud, University Paris-Sud; Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
authors: Laurent
authors: L
authors: Becquemont
authors: Linda
authors: L
authors: Benattar-Zibi
authors: Philippe
authors: P
authors: Bertin
authors: Gilles
authors: G
authors: Berrut
authors: Emmanuelle
authors: E
authors: Corruble
authors: Nicolas
authors: N
authors: Danchin
authors: Tiba
authors: T
authors: Delespierre
authors: Geneviève
authors: G
authors: Derumeaux
authors: Bruno
authors: B
authors: Falissard
authors: Francoise
authors: F
authors: Forette
authors: Olivier
authors: O
authors: Hanon
authors: Florence
authors: F
authors: Pasquier
authors: Michel
authors: M
authors: Pinget
authors: Rissane
authors: R
authors: Ourabah
authors: Céline
authors: C
authors: Piedvache
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000553:Ambulatory Care / Q000592:standards / Q000706:statistics & numerical data*; D001281:Atrial Fibrillation / Q000453:epidemiology / Q000628:therapy*; D059350:Chronic Pain / Q000453:epidemiology / Q000628:therapy*; D015331:Cohort Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology / Q000628:therapy*; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D012111:Residence Characteristics / Q000706:statistics & numerical data