title: Comparison of one-stage revision with antibiotic cement versus two-stage revision results for infected total hip arthroplasty.
abstract: Eighty three patients of infected total hip arthroplasty (THA) treated by implant removal and staged revision were retrospectively analyzed. Clinical characteristics and treatment outcomes were compared between three groups: 17 one-stage revisions (one-stage group), 44 two-stage revisions with second stage reimplantation (two-stage reimplanted group), and 22 planned two-stage but no reimplantation (two-stage non-reimplanted group). The rate of infection control was 82% (14/17) in the one-stage group, 75% (33/44) in the two-stage reimplanted group, and 68% (15/22) in the two-stage non-reimplanted group (P=0.60). The mean of latest Harris hip score was 77, 60, and 58 (P=0.14), and the UCLA activity score was 4.0, 4.2, and 3.6 (P=0.74) for each group, respectively. Results of this study suggest that one-stage revision arthroplasty can be a treatment option in selected cases of infected THA with a satisfactory infection control rate and functional outcomes comparable to those of two-stage revision.
authors: Harris Orthopedic Laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital, Boston, Massachusetts.
authors: Ho-Rim
authors: HR
authors: Choi
authors: Young-Min
authors: YM
authors: Kwon
authors: Andrew A
authors: AA
authors: Freiberg
authors: Henrik
authors: H
authors: Malchau
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001168:Arthritis / Q000601:surgery; D019644:Arthroplasty, Replacement, Hip / Q000295:instrumentation / Q000379:methods*; D001843:Bone Cements / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006622:Hip Prosthesis / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000601:surgery; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000188:drug therapy*; D012086:Reoperation / Q000295:instrumentation / Q000379:methods; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements
keywords: comparison; infection; one-stage revision; total hip arthroplasty; two-stage revision