title: West Nile virus RNA in tissues from donor associated with transmission to organ transplant recipients.
abstract: We identified West Nile virus (WNV) RNA in skin, fat, muscle, tendon, and bone marrow from a deceased donor associated with WNV transmission through solid organ transplantation. WNV could not be cultured from the RNA-positive tissues. Further studies are needed to determine if WNV can be transmitted from postmortem tissues.
authors: Dianna M
authors: DM
authors: Blau
authors: Ingrid B
authors: IB
authors: Rabe
authors: Julu
authors: J
authors: Bhatnagar
authors: Rachel
authors: R
authors: Civen
authors: Kavita K
authors: KK
authors: Trivedi
authors: Dominique
authors: D
authors: Rollin
authors: Susan N
authors: SN
authors: Hocevar
authors: Matthew
authors: M
authors: Kuehnert
authors: J Erin
authors: JE
authors: Staples
authors: Sherif R
authors: SR
authors: Zaki
authors: Marc
authors: M
authors: Fischer
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D016377:Organ Transplantation / Q000009:adverse effects; D016133:Polymerase Chain Reaction; D012367:RNA, Viral; D014019:Tissue Donors; D014901:West Nile Fever / Q000175:diagnosis / Q000635:transmission*; D014902:West Nile virus / Q000235:genetics*
chemical_list: D012367:RNA, Viral
keywords: RNA; WNV; West Nile virus; immunodeficiency; organ donor; organ transplantation; organs; solid organ transplantation; tissues; transplant; virus transmission; viruses
references: Transpl Infect Dis. 2012 Jun;14(3):268-77
references: 22606990
references: Clin Infect Dis. 2006 Jun 1;42(11):1527-35
references: 16652309
references: Cell Tissue Bank. 2012 Aug;13(3):499-511
references: 22134724
references: Am J Trop Med Hyg. 1954 Jan;3(1):19-50
references: 13114588
references: Hum Pathol. 2004 Aug;35(8):983-90
references: 15297965
references: N Engl J Med. 2003 Sep 25;349(13):1236-45
references: 14500806
references: Cornea. 1997 Mar;16(2):132-7
references: 9071524
references: MMWR Morb Mortal Wkly Rep. 2011 Dec 23;60(50):1697-700
references: 22189891
references: MMWR Surveill Summ. 2010 Apr 2;59(2):1-17
references: 20360671
references: N Engl J Med. 2003 May 29;348(22):2196-203
references: 12773646
references: Lancet. 2001 Jul 28;358(9278):261-4
references: 11498211
references: Brain Pathol. 2007 Oct;17(4):354-62
references: 17610522
references: Am J Trop Med Hyg. 2012 Feb;86(2):335-40
references: 22302871
references: J Clin Microbiol. 2000 Nov;38(11):4066-71
references: 11060069