title: Efficient metal-free synthesis of various pyrido[2',1':2,3]imidazo- [4,5-b]quinolines.
abstract: Dancing with diversity: The synthesis of diverse pyrido[2',1':2,3]imidazo[4,5-b]quinolines bearing several substitution patterns was developed based on combining a multicomponent reaction (Groebke-Blackburn-Bienaymé reaction) with an original cyclization as a secondary transformation (see scheme; DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene).
authors: Institut de Chimie Organique et Analytique (ICOA), Université d'Orléans, UMR-CNRS 7311, BP 6759, rue de Chartres, 45067 Orléans cedex 2 (France), Fax: (+33) 2-38-41-72-81.
authors: Mathieu
authors: M
authors: Arnould
authors: Marie-Aude
authors: MA
authors: Hiebel
authors: Stéphane
authors: S
authors: Massip
authors: Jean Michel
authors: JM
authors: Léger
authors: Christian
authors: C
authors: Jarry
authors: Sabine
authors: S
authors: Berteina-Raboin
authors: Gérald
authors: G
authors: Guillaumet
mesh_terms: D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000737:chemistry*; D003500:Cyclization; D008670:Metals / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; D008670:Metals; D011804:Quinolines; C031033:1,8-diazabicyclo(5.4.0)undec-7-ene
keywords: Groebke-Blackburn-Bienaymé reaction; aromatic cyclization; cyclization; diversity-oriented synthesis; multicomponent reactions