title: Brewer's Yeast Improves Blood Pressure in Type 2 Diabetes Mellitus.
abstract: BACKGROUND
  This study was conducted to investigate the effects of Brewer's yeast supplementation on serum lipoproteins and blood pressure in patients with Type 2 diabetes mellitus.
  
  
  METHODS
  In a randomized double blind clinical trial, 90 adults with type 2 diabetes mellitus were recruited, and divided randomly into 2 groups, trial group received brewer's yeast (1800 mg/day) and control group received placebo for 12 weeks. Weight, BMI, food consumption (based on 24 hour food recall), fasting serum lipoproteins (Cholesterol, Triglyceride, LDL-c, HDL-c), systolic and diastolic blood pressures were measured before and after the intervention. Data analyses were performed by Statistical Package for Social Sciences ver. 18.0, and the statistical tests included Independent t-test, Paired t-test, Kolmogorov-Smirnov and analysis of covariance. This trial was registered in Iranian Registry of Clinical Trials (IRCT), No.IRCT138807062513N1.
  
  
  RESULTS
  Eighty-four subjects (21 men and 63 women) aged 46.3±6.1 years completed the study. After 12 weeks supplementation, systolic and diastolic blood pressures were decreased in the group receiving brewer's yeast (4.1±1.5, P=0.007 and 5.7±0.6, P=0.001 respectively). No-significant changes in LDL-c, HDL-c, Triglyceride and Cholesterol were shown.
  
  
  CONCLUSIONS
  Supplementation with Brewer's yeast besides the usual treatment of type 2 diabetes mellitus can reduce systolic and diastolic blood pressures in diabetic patients.
authors: International Campus, Tehran University of Medical Sciences, Tehran, Iran.
authors: Payam
authors: P
authors: Hosseinzadeh
authors: Abolghassem
authors: A
authors: Djazayery
authors: Seyed-Ali
authors: SA
authors: Mostafavi
authors: Mohammad Hassan
authors: MH
authors: Javanbakht
authors: Hoda
authors: H
authors: Derakhshanian
authors: Abbas
authors: A
authors: Rahimiforoushani
authors: Mahmoud
authors: M
authors: Djalali
keywords: Blood pressure; Brewer’s yeast; Diabetes
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