title: The effect of a caffeinated mouth-rinse on endurance cycling time-trial performance.
abstract: The purpose of this study was to investigate if acute caffeine exposure via mouth-rinse improved endurance cycling time-trial performance in well-trained cyclists. It was hypothesized that caffeine exposure at the mouth would enhance endurance cycling time-trial performance. Ten well-trained male cyclists (mean ± SD: 32.9 ± 7.5 years, 74.7 ± 5.3 kg, 176.8 ± 5.1cm, VO₂peak = 59.8 ± 3.5 ml·kg⁻¹·min⁻¹) completed two experimental time-trials following 24 hr of dietary and exercise standardization. A randomized, double-blind, placebo-controlled, cross-over design was employed whereby cyclists completed a time-trial in the fastest time possible, which was equivalent work to cycling at 75% of peak aerobic power output for 60 min. Cyclists were administered 25 ml mouth-rinses for 10 s containing either placebo or 35 mg of anhydrous caffeine eight times throughout the time-trial. Perceptual and physiological variables were recorded throughout. No significant improvement in time-trial performance was observed with caffeine (3918 ± 243 s) compared with placebo mouth-rinse (3940 ± 227 s). No elevation in plasma caffeine was detected due to the mouth-rinse conditions. Caffeine mouth-rinse had no significant effect on rating of perceived exertion, heart rate, rate of oxygen consumption or blood lactate concentration. Eight exposures of a 35 mg dose of caffeine at the buccal cavity for 10s does not significantly enhance endurance cycling time-trial performance, nor does it elevate plasma caffeine concentration.
authors: Sport Performance Optimisation Research Team, School of Health Sciences, University of Tasmania, Tasmania Australia.
authors: Thomas M
authors: TM
authors: Doering
authors: James W
authors: JW
authors: Fell
authors: Michael D
authors: MD
authors: Leveritt
authors: Ben
authors: B
authors: Desbrow
authors: Cecilia M
authors: CM
authors: Shing
mesh_terms: D000284:Administration, Oral; D000328:Adult; D054874:Athletic Performance / Q000502:physiology*; D001642:Bicycling / Q000502:physiology*; D002110:Caffeine / Q000008:administration & dosage* / Q000097:blood / Q000494:pharmacology; D018592:Cross-Over Studies; D004311:Double-Blind Method; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D019344:Lactic Acid / Q000097:blood; D008297:Male; D009055:Mouth; D009067:Mouthwashes; D010101:Oxygen Consumption / Q000187:drug effects; D010465:Perception; D010807:Physical Endurance / Q000187:drug effects* / Q000502:physiology; D005082:Physical Exertion
chemical_list: D009067:Mouthwashes; D019344:Lactic Acid; D002110:Caffeine