title: CuBr for KA(2) reaction: en route to propargylic amines bearing a quaternary carbon center.
abstract: A highly efficient CuBr-catalyzed coupling of ketones, amines and alkynes (KA(2)) forming propargylic amines bearing a quaternary carbon center with the broadest scope so far has been developed.
authors: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, P. R. China.
authors: Xinjun
authors: X
authors: Tang
authors: Jinqiang
authors: J
authors: Kuang
authors: Shengming
authors: S
authors: Ma
mesh_terms: D000480:Alkynes / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis / Q000737:chemistry; D001965:Bromides / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry; D010293:Pargyline / Q000031:analogs & derivatives* / Q000737:chemistry; D011437:Propylamines / Q000737:chemistry*
chemical_list: D000480:Alkynes; D000588:Amines; D001965:Bromides; D007659:Ketones; D011437:Propylamines; C408079:cupric bromide; C009054:propargylamine; D002244:Carbon; D003300:Copper; D010293:Pargyline