title: Unprecedented synthesis of alkynylphosphine-boranes through room-temperature oxidative alkynylation.
abstract: An original and user-friendly synthesis of alkynylphosphine-boranes, useful building blocks in organic synthesis, based on an oxidative P-alkynylation reaction with readily available copper acetylides is reported. The ability of a secondary phosphine protected with a borane to undergo oxidative coupling without oxidation of the P-moiety is demonstrated for the first time. The reaction, which proceeds at room temperature, is applicable to the preparation of enantioenriched and structurally complex alkynylphosphine-boranes.
authors: Institut Lavoisier de Versailles, UMR CNRS 8180, Université de Versailles Saint-Quentin en Yvelines, 45, avenue des Etats-Unis, 78035 Versailles Cedex, France.
authors: Kévin
authors: K
authors: Jouvin
authors: Romain
authors: R
authors: Veillard
authors: Cédric
authors: C
authors: Theunissen
authors: Carole
authors: C
authors: Alayrac
authors: Annie-Claude
authors: AC
authors: Gaumont
authors: Gwilherm
authors: G
authors: Evano