title: Cell number regulator genes inPrunusprovide candidate genes for the control of fruit size in sweet and sour cherry.
abstract: Striking increases in fruit size distinguish cultivated descendants from small-fruited wild progenitors for fleshy fruited species such asSolanum lycopersicum(tomato) andPrunusspp. (peach, cherry, plum, and apricot). The first fruit weight gene identified as a result of domestication and selection was the tomatoFW2.2gene. Members of theFW2.2gene family in corn (Zea mays) have been namedCNR(Cell Number Regulator) and two of them exert their effect on organ size by modulating cell number. Due to the critical roles ofFW2.2/CNRgenes in regulating cell number and organ size, this family provides an excellent source of candidates for fruit size genes in other domesticated species, such as those found in thePrunusgenus. A total of 23FW2.2/CNRfamily members were identified in the peach genome, spanning the eightPrunuschromosomes. Two of theseCNRswere located within confidence intervals of major quantitative trait loci (QTL) previously discovered on linkage groups 2 and 6 in sweet cherry (Prunus avium), namedPavCNR12andPavCNR20, respectively. An analysis of haplotype, sequence, segregation and association with fruit size strongly supports a role ofPavCNR12in the sweet cherry linkage group 2 fruit size QTL, and this QTL is also likely present in sour cherry (P. cerasus). The finding that the increase in fleshy fruit size in both tomato and cherry associated with domestication may be due to changes in members of a common ancestral gene family supports the notion that similar phenotypic changes exhibited by independently domesticated taxa may have a common genetic basis.
authors: Dipartimento di Scienze Agrarie, Università degli Studi di Bologna, Bologna, Italy.
authors: P
authors: P
authors: De Franceschi
authors: T
authors: T
authors: Stegmeir
authors: A
authors: A
authors: Cabrera
authors: E
authors: E
authors: van der Knaap
authors: U R
authors: UR
authors: Rosyara
authors: A M
authors: AM
authors: Sebolt
authors: L
authors: L
authors: Dondini
authors: E
authors: E
authors: Dirlewanger
authors: J
authors: J
authors: Quero-Garcia
authors: J A
authors: JA
authors: Campoy
authors: A F
authors: AF
authors: Iezzoni
keywords: Cell number regulator; Cherry; Domestication; Fruit size; Marker-assisted selection; Prunus
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