title: Leveraging the national cyberinfrastructure for biomedical research.
abstract: In the USA, the national cyberinfrastructure refers to a system of research supercomputer and other IT facilities and the high speed networks that connect them. These resources have been heavily leveraged by scientists in disciplines such as high energy physics, astronomy, and climatology, but until recently they have been little used by biomedical researchers. We suggest that many of the 'Big Data' challenges facing the medical informatics community can be efficiently handled using national-scale cyberinfrastructure. Resources such as the Extreme Science and Discovery Environment, the Open Science Grid, and Internet2 provide economical and proven infrastructures for Big Data challenges, but these resources can be difficult to approach. Specialized web portals, support centers, and virtual organizations can be constructed on these resources to meet defined computational challenges, specifically for genomics. We provide examples of how this has been done in basic biology as an illustration for the biomedical informatics community.
authors: National Center for Genome Analysis Support, Indiana University, Bloomington, Indiana, USA.
authors: Richard
authors: R
authors: LeDuc
authors: Matthew
authors: M
authors: Vaughn
authors: John M
authors: JM
authors: Fonner
authors: Michael
authors: M
authors: Sullivan
authors: James G
authors: JG
authors: Williams
authors: Philip D
authors: PD
authors: Blood
authors: James
authors: J
authors: Taylor
authors: William
authors: W
authors: Barnett
mesh_terms: D035843:Biomedical Research / Q000458:organization & administration*; D003199:Computer Systems; D023281:Genomics; D033181:Information Dissemination / Q000379:methods*; D020407:Internet; D008490:Medical Informatics
keywords: Big Data; Genomics; National Cyberinfrastructure
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