title: [Prognostic role of C-reactive protein in progression of atherosclerosis in a year after coronary bypass surgery].
abstract: Aim of the study was to assess prognostic role of high sensitivity C-reactive protein (CRP) in progression of atherosclerosis in patients with ischemic heart disease (IHD) in a year after coronary artery bypass grafting (CABG). We examined 49 patients with stable IHD subjected to elective CABG (45 with and 4 without without cardiopulmonary bypass). In a year after surgery patients were divided into 2 groups: with (group 1, n=18, 36.7%) and without (group 2, n=31, 63.3%) progression of atherosclerosis of any localization. Contribution of various clinical and instrumental factors, type of intervention, CRP level before and in 1 year after surgery was analyzed. Before CABS CRP level was 3 times higher in group 1 compared with group 2 (=0.03). Increase of intima-media thickness was registered in a year after CABS in both groups, but it was significant only in patients with atherosclerosis progression (=0.04). Other clinical factors, gender characteristics of groups, type of intervention exerted no significant influence on progression of systemic atherosclerosis.
authors: Iu V
authors: IuV
authors: Baĭrakova
authors: E D
authors: ED
authors: Bazdyrev
authors: Ia V
authors: IaV
authors: Kazachek
authors: N A
authors: NA
authors: Kalichenko
authors: N A
authors: NA
authors: Bezdenezhnykh
authors: O V
authors: OV
authors: Gruzdeva
authors: S V
authors: SV
authors: Ivanov
authors: O V
authors: OV
authors: Barbarash
mesh_terms: D001158:Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology; D050197:Atherosclerosis / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D015415:Biomarkers / Q000032:analysis / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D059168:Carotid Intima-Media Thickness; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000379:methods; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood / Q000601:surgery; D011183:Postoperative Complications / Q000097:blood / Q000175:diagnosis; D011184:Postoperative Period; D011379:Prognosis; D015203:Reproducibility of Results
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein