title: [Effect of intermittent pneumatic compression on coagulation function and deep venous hemodynamics of lower limbs after rectal cancer resection].
abstract: OBJECTIVE
  To investigate the effects of intermittent pneumatic compression (IPC) on coagulation function, deep venous hemodynamics and prevention of deep venous thrombosis (DVT) of lower limbs in patients after rectal cancer resection.
  
  
  METHODS
  A total of 120 patients undergoing rectal cancer resection were randomly divided into non-IPC group (control group, n=60) and IPC group (n=60). The control group received routine treatment after resection and the IPC group received IPC based on the routine treatments. Prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB), international normalized ratio (INR) and volume of D-dimer (D-D) were detected before operation and 1-, 3-, 5- and 7-day after operation. Meanwhile, blood flow velocity and caliber of external iliac vein, femoral vein and popliteal vein were examined by color Doppler ultrasound, then the average blood flow velocity and blood flow volume were calculated.
  
  
  RESULTS
  Incidence of lower limb DVT was 13.3% (8/60) and 1.7% (1/60) in control group and IPC group respectively with significant difference (P<0.05). The differences in PT, APTT and INR were not significant (P>0.05) at 1-day after operation as compared to the preoperative level, while FIB and D-D both increased (P<0.05), all presented no significant difference among the two groups (P>0.05). PT shortened gradually (P<0.05), APTT and INR did not change significantly (P>0.05), FIB and D-D increased gradually (P<0.05), and no significant differences were found between the two groups at the same time point (all P>0.05). All the above parameters in the control group were significantly lower than those in IPC group (all P<0.05).
  
  
  CONCLUSIONS
  IPC can improve hemodynamics indexes of deep veins of lower limb in patients after rectal cancer operation, and prevent the lower limb DVT. IPC is a safe, simple and convenient physical therapy.
authors: Research Institute of General Surgery, Department of General Surgery, Fuzhou General Hospital of Nanjing Military Command, Fuzhou 350025, China. fzptwk@21cn.com.
authors: Jian-ping
authors: JP
authors: Wang
authors: Yu-dong
authors: YD
authors: Lin
authors: Lie
authors: L
authors: Wang
authors: Fang-gui
authors: FG
authors: Xu
authors: Yuan
authors: Y
authors: Gao
authors: Cheng-jin
authors: CJ
authors: Li
authors: Yin
authors: Y
authors: Xia
authors: Jian-Ping
authors: JP
authors: Zhu
authors: Zhong-Qiu
authors: ZQ
authors: Wu
mesh_terms: D000368:Aged; D005260:Female; D005268:Femoral Vein / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D048228:Intermittent Pneumatic Compression Devices; D035002:Lower Extremity / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011183:Postoperative Complications / Q000517:prevention & control; D012004:Rectal Neoplasms / Q000601:surgery; D020246:Venous Thrombosis / Q000209:etiology / Q000517:prevention & control*