title: Natural orifice transluminal endoscopic surgery (NOTES) for clinical management of intra-abdominal diseases.
abstract: Clinical research on natural orifice transluminal endoscopic surgery (NOTES) has been increasingly reported over the past 5 years and more than 1200 patients have received various NOTES procedures. The present article reviews the clinical practice of NOTES for the treatment of intra-abdominal diseases, and was carried out through systematic search with specific keywords in major databases for NOTES-related clinical literature. The last date of the search was 15 August, 2012. Transvaginal cholecystectomy is the commonest NOTES procedure reported, and its clinical feasibility and safety was established through prospective case series and randomized trials. There is a regional difference in NOTES development with the majority of NOTES fromCaucasian countries being transvaginal cholecystectomy and most reports from Asian countries being NOTES-related procedures. Safe closure of gastrointestinal access remains challenging, and novel endoscopic instruments are essential to enhance future development of NOTES.
authors: Department of Surgery, Chinese University of Hong Kong, Hong Kong, China.
authors: Liu
authors: L
authors: Liu
authors: Philip W Y
authors: PW
authors: Chiu
authors: Nagewasher
authors: N
authors: Reddy
authors: Khek-Yu
authors: KY
authors: Ho
authors: Seigo
authors: S
authors: Kitano
authors: Dong Wan
authors: DW
authors: Seo
authors: Hisao
authors: H
authors: Tajiri
mesh_terms: D000007:Abdominal Injuries / Q000209:etiology; D001062:Appendectomy / Q000379:methods; D002763:Cholecystectomy / Q000379:methods; D004939:Esophageal Perforation / Q000209:etiology; D005767:Gastrointestinal Diseases / Q000601:surgery*; D006801:Humans; D022125:Lacerations / Q000209:etiology; D057605:Natural Orifice Endoscopic Surgery / Q000009:adverse effects* / Q000379:methods*; D011446:Prospective Studies
keywords: natural orifice transluminal endoscopic surgery (NOTES); transgastric endoscopic cholecystectomy; transgastric endoscopic peritoneoscopy; transvaginal endoscopic cholecystectomy