title: Reduction of prevalence of persistent BVDV infection in cattle herds by long-term vaccination program (preliminary clinical study).
abstract: Effectiveness of long-term anti-BVDV vaccination program in reducing prevalence of persistent BVDV infection in cattle herds was evaluated in seven years observational study (2005-2011). Among three seropositive dairy cattle herds (within herd seroprevalence 100%, confirmed by ELISA Herd Check BVDV Ab, IDEXX, Sweden) vaccination program based on inactivated vaccine (cytopathic strain 5960) was commenced in 2007 in two herds and continued till 2010. In the years 2007-2011 all calves aged 2-12 weeks in all three herds were tested yearly with RT-PCR in order to detect persistently infected individuals. For the entire study period true prevalence of BVDV persistent infection was significantly lower in vaccinated than in non-vaccinated herd. This may imply the role of long-term vaccination program in reducing prevalence of persistent BVDV infection in cattle herds.
authors: Division of Infectious Diseases and Veterinary Administration, Department of Epizootiology with Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, University of Environmental and Life Sciences, Pl. Grunwaldzki 45, 50-366 Wrocław, Poland. krzysztof.rypula@up.wroc.pl
authors: K
authors: K
authors: Rypuła
authors: K
authors: K
authors: Płoneczka-Janeczko
authors: J
authors: J
authors: Bania
authors: E
authors: E
authors: Wałecka
authors: K
authors: K
authors: Bierowiec
authors: W
authors: W
authors: Rozpedek
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000097:blood / Q000453:epidemiology / Q000517:prevention & control*; D002417:Cattle; D003612:Dairying; D001908:Diarrhea Viruses, Bovine Viral; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D015995:Prevalence; D012680:Sensitivity and Specificity; D013997:Time Factors; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines