title: Comparison of central line-associated bloodstream infection rates when changing to a zero fluid displacement intravenous needleless connector in acute care settings.
abstract: This was a multicenter, quasiexperimental, 140-month, acute care study comparing central line-associated bloodstream infection rates associated with positive or negative intravenous connectors to a zero fluid displacement connector. A decrease in central line-associated bloodstream infections was found after changing from either negative or positive intravenous connectors to the zero fluid displacement connector (P = .004) with total cost savings of over $3 million.
authors: Georgia Regents University, Augusta, GA. Electronic address: cchernecky@gru.edu.
authors: Cynthia C
authors: CC
authors: Chernecky
authors: Nurse Consultant, Marietta, GA.
authors: Denise
authors: D
authors: Macklin
authors: Jason & Jarvis Associates, LLC, Hilton Head Island, SC.
authors: William R
authors: WR
authors: Jarvis
authors: Georgia Regents University, Augusta, GA.
authors: Thomas V
authors: TV
authors: Joshua
mesh_terms: D055499:Catheter-Related Infections / Q000453:epidemiology*; D002406:Catheterization, Peripheral / Q000009:adverse effects* / Q000379:methods*; D006801:Humans
keywords: CLABSI; Comparative effectiveness; Mechanical valve; Negative pressure; Neutral; Positive pressure; Split septum