title: [Mediastinitis after esophageal perforation].
abstract: BACKGROUND
  Assessment of therapy in patients with mediastinal infection resulting from esophageal perforation.
  
  
  METHODS
  Retrospective (2008-2012) processing of a group of surgically treated patients. The aspects assessed were aetiology, the surgical methods applied and the length of therapy.
  
  
  RESULTS
  The total number of patients treated was 16. In 8 cases, the aetiology was iatrogenic (3 cases of leaking esophageal anastomosis in consequence of resection of the esophagus, 2 cases of perforation after fundoplication, 1 case of esophageal cardiomyotomy, and 2 cases of perforation during endoscopy). In 4 patients, the aetiology was spontaneous perforation, impacted foreign bodies caused difficulties to 3 patients, and the last cause was acid corrosive esophagitis. A stent was applied in all the patients at the site of the defect. The mediastinitis was drained through the access from thoracotomy or left thoracolaparotomy, respectively (8 cases), or by combination of laparotomy/laparostomy and pleural drainage (5 cases). Pleural (in 3 cases) and neck (1 case) drainage meant minimum intervention. Esophagectomy was not carried out in any of the patients. 4 patients died. The average period of time for which the stent was left in situ was 53.7 days; the average time of hospitalization in surviving patients was 53.4 days.
  
  
  CONCLUSIONS
  Stent application does not show any difference regarding patients' survival (25% mortality), but enables shortening the total therapy time and, predominantly, preserving the native esophagus.
authors: Chirurgickfá klinika FN Plzen. safranek@fnplzen.cz
authors: J
authors: J
authors: Safránek
authors: J
authors: J
authors: Geiger
authors: J
authors: J
authors: Klecka
authors: T
authors: T
authors: Skalický
authors: V
authors: V
authors: Spidlen
authors: V
authors: V
authors: Veselý
authors: J
authors: J
authors: Vodicka
mesh_terms: D000328:Adult; D000368:Aged; D004939:Esophageal Perforation / Q000150:complications* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology; D008875:Middle Aged; D015607:Stents