title: Excessive gestational weight gain over multiple pregnancies and the prevalence of obesity at age 40.
abstract: OBJECTIVE
  Although several studies have found an association between excessive gestational weight gain (GWG) and obesity later in life, to the best of our knowledge, no studies have explored the role of GWG events across the life course.
  
  
  METHODS
  We describe how the prevalence of midlife obesity (BMI⩾30 at age 40 or 41) among women varies by life course patterns of GWG (using 2009 IOM guidelines) in the USA's National Longitudinal Survey of Youth 1979 cohort.
  
  
  RESULTS
  Among women who reported 1-3 births before age 40, the prevalence of midlife obesity increased with a rising number of excessive GWG events: from none (23.4%, n=875) to one (37.6%, n=707), from none (23.4%, n=875) to two (46.8%, n=427) and from none (23.4%, n=875) to three (54.6%, n=108), P<0.00005 for trend. Obesity prevalence was similar for the same number of excessive GWG events, regardless of parity. No clear pattern emerged for the sequencing of excessive GWG event(s) and later obesity.
  
  
  CONCLUSIONS
  In our descriptive exploratory study, excessive GWG events appear to be associated with increased prevalence of obesity for parous women, suggesting the importance of preventive interventions regardless of timing of pregnancy-related weight changes over the life course.
authors: Division of Epidemiology, University of California Berkeley School of Public Health, Berkeley, CA, USA.
authors: A K
authors: AK
authors: Cohen
authors: Division of Epidemiology, University of California Berkeley School of Public Health, Berkeley, CA, USA.
authors: B W
authors: BW
authors: Chaffee
authors: Division of General Medical Disciplines, Stanford University School of Medicine, Stanford, CA, USA.
authors: D H
authors: DH
authors: Rehkopf
authors: Division of Biostatistics, University of California Berkeley School of Public Health, Berkeley, CA, USA.
authors: J R
authors: JR
authors: Coyle
authors: 1] Division of Epidemiology, University of California Berkeley School of Public Health, Berkeley, CA, USA [2] Division of Community Health and Human Development, University of California Berkeley School of Public Health, Berkeley, CA, USA.
authors: B
authors: B
authors: Abrams
mesh_terms: D000328:Adult; D015992:Body Mass Index; D005260:Female; D017408:Guidelines as Topic; D006801:Humans; D008019:Life Style; D008137:Longitudinal Studies; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology* / Q000517:prevention & control; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000517:prevention & control; D011272:Pregnancy, Multiple / Q000706:statistics & numerical data*; D015995:Prevalence; D011795:Surveys and Questionnaires; D015430:Weight Gain
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