title: Electroconvulsive therapy attenuates dendritic arborization in the basolateral amygdala.
abstract: Stress and depression are associated with aberrant neuroplasticity in the amygdala: there is increased dendritic arborization and synaptogenesis, perhaps explaining the increased anxiety and fear that are often apparent in depressed patients. Light microscopy images are presented, which show that 6 once-daily high (but not low)-dose electroconvulsive shocks attenuated dendritic arborization in the basolateral amygdala of Wistar rats, which changes were apparent even 1 month after the last electroconvulsive shock. These changes may explain a part of the mechanism of action of electroconvulsive therapy in conditions such as depression and posttraumatic stress disorder.
authors: Department of Anatomy, St. John's Medical College, Bangalore, India.
authors: Nagarchi
authors: N
authors: Khaleel
authors: Ravindranath
authors: R
authors: Roopa
authors: Jangama S M
authors: JS
authors: Smitha
authors: Chittaranjan
authors: C
authors: Andrade
mesh_terms: D000679:Amygdala / Q000502:physiology* / Q000648:ultrastructure; D000818:Animals; D003712:Dendrites / Q000502:physiology* / Q000648:ultrastructure; D004565:Electroconvulsive Therapy / Q000009:adverse effects*; D008297:Male; D009473:Neuronal Plasticity / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar