title: Treatment of neonatal progressive ventricular dilatation: a single-centre experience.
abstract: OBJECTIVE
  To describe our experience with a cohort of 295 infants with progressive ventricular dilatation occurring in the antenatal or neonatal period.
  
  
  METHODS
  A search was performed in our cranial ultrasound database. All records and images of infants in whom an imaging diagnosis of progressive ventricular dilatation had been made were retrieved. In addition, modes of treatment were analysed.
  
  
  RESULTS
  Between February 1991 and March 2012, 295 neonates were admitted to our level 3 neonatal intensive care unit (NICU), and developed progressive ventricular dilatation for which they required intervention. In the majority of these infants, progressive ventricular dilatation developed following IVH grade III or IV (240/295; 81%) of whom 214/240 (89%) were preterms. Temporary treatment with lumbar punctures and punctures from ventricular reservoirs was sufficient for the majority of the preterms. A ventricular reservoir was inserted in 216/295 infants (73%). The overall infection rate was low (6%). A ventriculoperitoneal shunt (VP shunt) was inserted in 32% of the whole cohort, revision within 3 months was necessary in 20%, and shunt-related infection occurred in 12%.
  
  
  CONCLUSIONS
  This large, single-centre cohort study reports the management of progressive ventricular dilatation in newborn infants. We have shown that with our approach, complications stay within acceptable limits.
authors: a Departments of Neonatology and.
authors: A J
authors: AJ
authors: Brouwer
authors: a Departments of Neonatology and.
authors: F
authors: F
authors: Groenendaal
authors: b Department of Neurosurgery , Wilhelmina Children's Hospital, University Medical Centre Utrecht , Utrecht , The Netherlands.
authors: K S
authors: KS
authors: Han
authors: a Departments of Neonatology and.
authors: L S
authors: LS
authors: de Vries
mesh_terms: D001927:Brain Diseases / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D057785:Catheters; D002552:Cerebral Ventricles / Q000473:pathology*; D015331:Cohort Studies; D004108:Dilatation, Pathologic; D006801:Humans; D006849:Hydrocephalus; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D007363:Intensive Care Units, Neonatal; D020300:Intracranial Hemorrhages / Q000150:complications*; D013129:Spinal Puncture; D016896:Treatment Outcome; D017287:Ventriculoperitoneal Shunt
keywords: Hydrocephalus; IVH; PHVD; preterm