title: Effect of treatment for 12 weeks with rilapladib, a lipoprotein-associated phospholipase A2 inhibitor, on arterial inflammation as assessed with 18F-fluorodeoxyglucose-positron emission tomography imaging.
authors: Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address: atawakol@partners.org.
authors: Ahmed
authors: A
authors: Tawakol
authors: Cardiac MR-PET-CT Program, Division of Cardiac Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
authors: Parmanand
authors: P
authors: Singh
authors: Division of Cardiovascular Medicine, University of Cambridge, Cambridge, United Kingdom.
authors: James H F
authors: JH
authors: Rudd
authors: Metabolic Pathways and Cardiovascular Therapeutic Area, GlaxoSmithKline, King of Prussia, Pennsylvania.
authors: Joseph
authors: J
authors: Soffer
authors: Metabolic Pathways and Cardiovascular Therapeutic Area, GlaxoSmithKline, King of Prussia, Pennsylvania.
authors: Gengqian
authors: G
authors: Cai
authors: Cardiac MR-PET-CT Program, Division of Cardiac Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
authors: Esad
authors: E
authors: Vucic
authors: Metabolic Pathways and Cardiovascular Therapeutic Area, GlaxoSmithKline, King of Prussia, Pennsylvania.
authors: Sarah P
authors: SP
authors: Brannan
authors: Metabolic Pathways and Cardiovascular Therapeutic Area, GlaxoSmithKline, King of Prussia, Pennsylvania.
authors: Elizabeth A
authors: EA
authors: Tarka
authors: Metabolic Pathways and Cardiovascular Therapeutic Area, GlaxoSmithKline, King of Prussia, Pennsylvania.
authors: Bonnie C
authors: BC
authors: Shaddinger
authors: Metabolic Pathways and Cardiovascular Therapeutic Area, GlaxoSmithKline, King of Prussia, Pennsylvania.
authors: Lea
authors: L
authors: Sarov-Blat
authors: Metabolic Pathways and Cardiovascular Therapeutic Area, GlaxoSmithKline, King of Prussia, Pennsylvania; Division of Brain Sciences, Imperial College London, London, United Kingdom.
authors: Paul
authors: P
authors: Matthews
authors: Cardiac MR-PET-CT Program, Division of Cardiac Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
authors: Sharath
authors: S
authors: Subramanian
authors: Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Peter Munk Cardic Centre and the Heart and Stroke Richard Lewar Centre of Excellence, University of Toronto, Toronto, Ontario, Canada.
authors: Michael
authors: M
authors: Farkouh
authors: Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Zahi A
authors: ZA
authors: Fayad
mesh_terms: D043203:1-Alkyl-2-acetylglycerophosphocholine Esterase / Q000037:antagonists & inhibitors*; D001167:Arteritis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D019788:Fluorodeoxyglucose F18; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D064801:Phospholipase A2 Inhibitors / Q000008:administration & dosage*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D016032:Randomized Controlled Trials as Topic; D013997:Time Factors
chemical_list: D064801:Phospholipase A2 Inhibitors; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D043203:1-Alkyl-2-acetylglycerophosphocholine Esterase