title: Yield of screening for TB and HIV among children failing to thrive in Botswana.
abstract: BACKGROUND
  Failure to thrive (FTT) is a sign of tuberculosis (TB) and human immunodeficiency virus (HIV) infection. We assessed TB and HIV prevalence in children with FTT at one clinic in Botswana.
  
  
  METHODS
  In July 2010, we screened all children attending a 'Well Child' clinic for FTT. Children with FTT were referred to a paediatrician who: (i) assessed causes of FTT, (ii) evaluated for HIV and TB and (iii) reviewed the patient chart for evaluations for TB and HIV.
  
  
  RESULTS
  Of 919 children screened, 176 (19%) had FTT. One hundred eighteen (67%) children saw a paediatrician, and of these, 95 (81%) completed the TB evaluation. TB was newly diagnosed in 6 of 95 (6%). At review, HIV status was known in 23 of 118 (19%). Ninety-five had an unknown HIV status. Forty-five (47%) tested for HIV; all tested HIV-negative.
  
  
  CONCLUSIONS
  TB and HIV screening among children with FTT diagnosed TB in 6% of cases completing an evaluation, but no new HIV infections.
authors: Botswana-UPenn Partnership, Gaborone, Botswana.
authors: Tonya
authors: T
authors: Arscott-Mills
authors: Ari
authors: A
authors: Ho-Foster
authors: Margaret
authors: M
authors: Lowenstein
authors: Haruna
authors: H
authors: Jibril
authors: Japhter
authors: J
authors: Masunge
authors: Phanuel
authors: P
authors: Mweemba
authors: Paul
authors: P
authors: Nashara
authors: Robert
authors: R
authors: Makombe
authors: Joconiah
authors: J
authors: Chirenda
authors: Harvey M
authors: HM
authors: Friedman
authors: Andrew P
authors: AP
authors: Steenhoff
authors: Nurit
authors: N
authors: Harari
mesh_terms: D001902:Botswana / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005183:Failure to Thrive / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D008297:Male; D008403:Mass Screening / Q000379:methods*; D010043:Outcome and Process Assessment, Health Care; D010044:Outpatient Clinics, Hospital; D015995:Prevalence; D012959:Socioeconomic Factors; D014376:Tuberculosis / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology*; D014505:Urban Population / Q000706:statistics & numerical data
keywords: HIV; children; failure to thrive; tuberculosis
references: Am J Respir Crit Care Med. 2007 Feb 15;175(4):367-416
references: 17277290
references: Pediatrics. 2006 Nov;118(5):e1350-9
references: 17079536
references: Pediatr Infect Dis J. 2010 Feb;29(2):e11-8
references: 19935116
references: Clin Infect Dis. 2008 Jan 15;46(2):289-95
references: 18171265
references: Arch Dis Child. 1982 May;57(5):347-51
references: 6807215
references: Pediatr AIDS HIV Infect. 1996 Apr;7(2):83-90
references: 11361485
references: Eur J Pediatr. 2009 Nov;168(11):1285-90
references: 19396462
references: Arch Dis Child. 2005 Nov;90(11):1171-4
references: 15964862
references: Pediatr Infect Dis J. 2002 Nov;21(11):1053-61
references: 12442029