title: A delayed, unusual non-cardiogenic pulmonary edema after intravascular administration of non-ionic, low osmolar radiocontrast media for coronary angiography.
abstract: Non-cardiogenic pulmonary edema (NCPE) is a rare adverse reaction to iodinated radiocontrast media (RCM), in which all previous cases were immediate reactions. A 56-year-old male was given iopamidol, a non-ionic, low osmolar RCM, during coronary artery angiography. He developed pulmonary edema and fever a day after the procedure. Despite diuretic therapy, the patient's pulmonary edema worsened and his high fever persisted. The patient's pulmonary edema was eventually resolved with intravenous steroid treatment. We interpreted the patient's condition as NCPE manifesting as a delayed reaction to RCM. To our knowledge, our case is the first to show NCPE as a delayed hypersensitivity reaction.
authors: Division of Cardiology, Department of Medicine, Seoul Paik Hospital, Inje University School of Medicine, Seoul, Korea.
authors: Min-Ho
authors: MH
authors: Kang
authors: Jong-Chun
authors: JC
authors: Nah
keywords: Contrast media; Hypersensitivity; Pulmonary edema
references: Eur Radiol. 2000;10(12):1965-75
references: 11305580
references: Lancet. 2002 Mar 23;359(9311):1037-8
references: 11937188
references: Immunol Allergy Clin North Am. 2009 Aug;29(3):453-68
references: 19563991
references: Emerg Radiol. 2006 Jul;12(5):210-5
references: 16688432
references: Eur Radiol. 2011 Nov;21(11):2305-10
references: 21779853
references: Ann Allergy Asthma Immunol. 1995 Oct;75(4):308-10
references: 7583844
references: Allergy. 2005 Feb;60(2):150-8
references: 15647034
references: J Invasive Cardiol. 2009 Oct;21(10):548-51
references: 19805846
references: J Allergy Clin Immunol. 1995 Nov;96(5 Pt 1):698-9
references: 7499690
references: Eur Radiol. 2003 Jan;13(1):181-4
references: 12541128
references: Curr Opin Allergy Clin Immunol. 2002 Aug;2(4):333-9
references: 12130948
references: Acta Radiol. 1998 Jan;39(1):81-3
references: 9498876
references: Acta Radiol. 1996 Sep;37(5):823-5
references: 8915300
references: No Shinkei Geka. 2005 Jul;33(7):703-7
references: 16001811
references: Pediatr Radiol. 2001 Aug;31(8):597-9
references: 11550775