title: Complete genome sequences of three rabies viruses isolated from rabid raccoon dogs and a cow in Korea.
abstract: The complete genomes of three rabies viruses (BD0406CC, BV9901PJ, and 08F40) of two raccoon dogs (Nyctereutes procyonoides koreensis) and a cow were determined. The genomic organization is typical of rabies viruses, and the open reading frames of the N, P, M, G, and L genes are 1,353, 894, 609, 1,575, and 6,384 bases in length, respectively. The full genome length of the three strains was 11,928 nucleotides, and the sequence similarity between the rabies viruses at the nucleotide level was 98.5-99.5%. Sequence comparisons indicated that these rabies viruses belong to the "Arctic and Arctic-like" group, with high homology to the Eurasian cluster. All Korean strains were clustered with the Mongolia strains, which belong to Arctic-like 1 clade. The 08F40 and BD0406CC strains were constructed with rabies virus strains isolated in Gangwon province. The BV9901PJ strain was closely related to strains isolated in Gyeonggi province in Korea. Three strains were more dependent upon geographical distribution and time period than host species. Complete genome sequencing of different host-origin rabies viruses will provide information that should contribute to understanding the transmission cycle and genetic variability of rabies from different hosts.
authors: Viral Disease Diagnostic Laboratory, Animal Disease Diagnostic Division, Animal, Plant and Fisheries Quarantine and Inspection Agency, 480 Anyang-6-Dong, Anyang, 430-824, Republic of Korea.
authors: Jae-Ku
authors: JK
authors: Oem
authors: Seong-Hee
authors: SH
authors: Kim
authors: Yeon-Hee
authors: YH
authors: Kim
authors: Myoung-Heon
authors: MH
authors: Lee
authors: Kyoung-Ki
authors: KK
authors: Lee
mesh_terms: D000818:Animals; D001483:Base Sequence; D002417:Cattle; D002418:Cattle Diseases / Q000821:virology*; D016679:Genome, Viral; D008969:Molecular Sequence Data; D010802:Phylogeny; D011818:Rabies / Q000662:veterinary* / Q000821:virology; D011820:Rabies virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology; D046031:Raccoon Dogs / Q000821:virology*; D056910:Republic of Korea; D014764:Viral Proteins / Q000235:genetics
chemical_list: D014764:Viral Proteins
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