title: Attention deficit hyperactivity disorder in cocaine-dependent adults: a psychiatric comorbidity analysis.
abstract: OBJECTIVE
  Attention deficit hyperactivity disorder (ADHD) is highly prevalent among drug abusers. We studied the psychiatric comorbidity and characteristics of cocaine use in relation to the presence of ADHD among patients with cocaine dependence.
  
  
  METHODS
  A total of 200 cocaine-dependent patients attending an Outpatient Drug Clinic participated in the study. A systematic evaluation of ADHD (CAADID-II), the severity of addiction (EuropASI) and other axes I and II psychiatric disorders was made (SCID-I and SCID-II). A descriptive, bivariate, and multivariate analysis of the data was performed.
  
  
  RESULTS
  In the multivariate analysis, the identified risk factors for the development of ADHD were a history of behavioral disorder in childhood (OR: 3.04), a lifetime history of cannabis dependence in the course of life (OR: 2.68), and age at the start of treatment (OR: 1.08). The bivariate analysis showed ADHD to be associated with other factors such as male gender, age at start of cocaine use and dependence, the amount of cocaine consumed weekly, increased occupational alteration, alcohol consumption, general psychological discomfort, depressive disorder, and antisocial personality disorder.
  
  
  CONCLUSIONS
  We conclude that ADHD is associated with increased psychiatric comorbidity and greater severity of addiction.
authors: Servei de Psiquiatria, Hospital Universitari Vall d'Hebron, CIBERSAM, Department of Psychiatry, Universitat Autònoma de Barcelona, Spain. cdaigre@vhebron.net
authors: Constanza
authors: C
authors: Daigre
authors: Carlos
authors: C
authors: Roncero
authors: Lara
authors: L
authors: Grau-López
authors: Nieves
authors: N
authors: Martínez-Luna
authors: Gemma
authors: G
authors: Prat
authors: Sergi
authors: S
authors: Valero
authors: Rosa
authors: R
authors: Tejedor
authors: Josep A
authors: JA
authors: Ramos-Quiroga
authors: Miguel
authors: M
authors: Casas
mesh_terms: D000328:Adult; D000367:Age Factors; D001289:Attention Deficit Disorder with Hyperactivity / Q000453:epidemiology* / Q000209:etiology / Q000523:psychology; D019970:Cocaine-Related Disorders / Q000453:epidemiology* / Q000209:etiology / Q000523:psychology; D015897:Comorbidity; D003430:Cross-Sectional Studies; D004651:Employment / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D002189:Marijuana Abuse / Q000453:epidemiology; D015999:Multivariate Analysis; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors