title: Thermally induced process-related contaminants: the example of acrolein and the comparison with acrylamide: opinion of the Senate Commission on Food Safety (SKLM) of the German Research Foundation (DFG).
abstract: α,β-Unsaturated aliphatic carbonyl compounds are naturally widespread in food, but are also formed during the thermal treatment of food. This applies, for example, to the genotoxic carcinogen acrylamide (AA), but also to acrolein (AC), the simplest α,β-unsaturated aldehyde. First observations indicate that human exposure to AC may be higher than the exposure to AA. The DFG Senate Commission on Food Safety therefore compared data on AC and AA available in the scientific literature, evaluating current knowledge on formation, occurrence, exposure, metabolism, biological effects, toxicity, and carcinogenicity and defined knowledge gaps as well as research needs in an opinion on November 19, 2012, in German. The English version was agreed on April 17, 2013.
authors: Department of Food Chemistry and Toxicology, University of Kaiserslautern, Kaiserslautern, Germany.
authors: Sabine
authors: S
authors: Guth
authors: Michael
authors: M
authors: Habermeyer
authors: Matthias
authors: M
authors: Baum
authors: Pablo
authors: P
authors: Steinberg
authors: Alfonso
authors: A
authors: Lampen
authors: Gerhard
authors: G
authors: Eisenbrand
mesh_terms: D000171:Acrolein / Q000737:chemistry* / Q000493:pharmacokinetics / Q000633:toxicity*; D020106:Acrylamide / Q000737:chemistry* / Q000493:pharmacokinetics / Q000633:toxicity*; D000818:Animals; D004781:Environmental Exposure / Q000032:analysis; D005506:Food Contamination / Q000032:analysis*; D059022:Food Safety; D005858:Germany; D006077:Government Agencies; D006361:Heating; D006801:Humans; D018675:Toxicity Tests
chemical_list: D020106:Acrylamide; D000171:Acrolein
keywords: Acrolein; Acrylamide; Exposure; Glycidamide; Mercapturic acids