title: Examining the cognitive effects of a special extract of Bacopa monniera (CDRI08: Keenmnd): a review of ten years of research at Swinburne University.
abstract: Bacopa monniera (EBm), an Indian aquatic herb, has been used in traditional Ayurvedic medicine for centuries for indications related to memory and inflammation. More recently specific extracts of EBm have emerged that have been subjected to rigorous in vitro, animal and now human clinical trials. In this paper we discuss some of these studies with special reference to mechanisms and efficacy of a special extract of Bacopa (CDRI08). Studies using this extract indicate that CDRI08 has several modes of action on the human brain. Promising indications for use in humans include improving cognition in the elderly and in patients with neurodegenerative disorders.
authors: Swinburne Centre for Human Psychopharmacology, Swinburne University, Hawthorn, Melbourne, Victoria, Australia. cstough@swin.edu.au
authors: Con
authors: C
authors: Stough
authors: Andrew
authors: A
authors: Scholey
authors: Vanessa
authors: V
authors: Cropley
authors: Keith
authors: K
authors: Wesnes
authors: Andrea
authors: A
authors: Zangara
authors: Matthew
authors: M
authors: Pase
authors: Karen
authors: K
authors: Savage
authors: Karen
authors: K
authors: Nolidin
authors: Justine
authors: J
authors: Lomas
authors: Luke
authors: L
authors: Downey
mesh_terms: D000818:Animals; D001315:Australia; D034681:Bacopa; D003071:Cognition / Q000187:drug effects; D006801:Humans; D018697:Nootropic Agents / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D014495:Universities
chemical_list: D018697:Nootropic Agents; D010936:Plant Extracts