title: Neural mechanisms of communicative innovation.
abstract: Human referential communication is often thought as coding-decoding a set of symbols, neglecting that establishing shared meanings requires a computational mechanism powerful enough to mutually negotiate them. Sharing the meaning of a novel symbol might rely on similar conceptual inferences across communicators or on statistical similarities in their sensorimotor behaviors. Using magnetoencephalography, we assess spectral, temporal, and spatial characteristics of neural activity evoked when people generate and understand novel shared symbols during live communicative interactions. Solving those communicative problems induced comparable changes in the spectral profile of neural activity of both communicators and addressees. This shared neuronal up-regulation was spatially localized to the right temporal lobe and the ventromedial prefrontal cortex and emerged already before the occurrence of a specific communicative problem. Communicative innovation relies on neuronal computations that are shared across generating and understanding novel shared symbols, operating over temporal scales independent from transient sensorimotor behavior.
authors: Radboud University Nijmegen, Donders Institute for Brain, Cognition, and Behaviour, Nijmegen 6500 HB, The Netherlands. a.stolk@donders.ru.nl
authors: Arjen
authors: A
authors: Stolk
authors: Lennart
authors: L
authors: Verhagen
authors: Jan-Mathijs
authors: JM
authors: Schoffelen
authors: Robert
authors: R
authors: Oostenveld
authors: Mark
authors: M
authors: Blokpoel
authors: Peter
authors: P
authors: Hagoort
authors: Iris
authors: I
authors: van Rooij
authors: Ivan
authors: I
authors: Toni
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000033:anatomy & histology / Q000502:physiology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000502:physiology; D003142:Communication; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008297:Male; D009415:Nerve Net / Q000033:anatomy & histology / Q000502:physiology*; D017397:Prefrontal Cortex / Q000033:anatomy & histology / Q000502:physiology; D011340:Problem Solving / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology; D012919:Social Behavior; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000502:physiology; D055815:Young Adult
keywords: MEG; broadband spectral change; experimental semiotics; social interaction; theory of mind
references: Trends Neurosci. 2013 Mar;36(3):141-51
references: 23273272
references: J Cogn Neurosci. 2008 Apr;20(4):580-91
references: 18052777
references: Comput Intell Neurosci. 2011;2011:156869
references: 21253357
references: Trends Cogn Sci. 2013 Mar;17(3):105-6
references: 23384658
references: Front Hum Neurosci. 2012 Jun 27;6:185
references: 22754517
references: Front Hum Neurosci. 2012 Sep 05;6:251
references: 22973215
references: Front Hum Neurosci. 2012 Sep 25;6:253
references: 23055960
references: Neuroimage. 2005 Apr 15;25(3):653-60
references: 15808966
references: J Neurosci. 2008 Mar 5;28(10):2539-50
references: 18322098
references: Neuroimage. 1997 May;5(4 Pt 1):261-70
references: 9345555
references: J Neurosci. 2001 Jun 15;21(12):RC150
references: 11404442
references: Behav Brain Sci. 2004 Apr;27(2):169-90; discussion 190-226
references: 15595235
references: Trends Cogn Sci. 2004 Nov;8(11):501-7
references: 15491904
references: Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14425-30
references: 20660768
references: Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2717-22
references: 20133780
references: PLoS Comput Biol. 2009 Dec;5(12):e1000609
references: 20019800
references: Front Hum Neurosci. 2009 Jul 30;3:14
references: 19668699
references: Neuroimage. 2013 Mar;68:39-48
references: 23246857
references: Front Neurosci. 2010 Dec 08;4:188
references: 21151781
references: J Neurosci. 2011 Feb 23;31(8):2906-15
references: 21414912
references: Trends Cogn Sci. 2012 Feb;16(2):114-21
references: 22221820
references: Nat Neurosci. 2005 Dec;8(12):1667-76
references: 16299501
references: J Neurosci. 2010 May 12;30(19):6477-9
references: 20463210
references: Curr Biol. 2008 Mar 25;18(6):454-7
references: 18356050
references: J Neurosci. 2009 Oct 28;29(43):13613-20
references: 19864573
references: Nat Rev Neurosci. 2002 Jun;3(6):463-71
references: 12042881
references: Nat Rev Neurosci. 2003 Mar;4(3):179-92
references: 12612631
references: Cognition. 2009 Apr;111(1):46-54
references: 19201397
references: Nat Rev Neurosci. 2012 May 18;13(6):407-20
references: 22595786
references: Nature. 2009 Jul 2;460(7251):94-7
references: 19506558
references: Cogn Sci. 2005 Sep 10;29(5):737-67
references: 21702792
references: Science. 1996 Sep 27;273(5283):1868-71
references: 8791593
references: PLoS Biol. 2005 Mar;3(3):e79
references: 15736981
references: J Neurosci. 2013 Jan 23;33(4):1684-95
references: 23345241
references: J Neurosci Methods. 2007 Aug 15;164(1):177-90
references: 17517438
references: Front Hum Neurosci. 2011 Jun 30;5:52
references: 21747765
references: Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):694-9
references: 11209067
references: Annu Rev Neurosci. 2012;35:203-25
references: 22443509
references: Annu Rev Psychol. 2009;60:693-716
references: 18771388
references: Neuron. 2009 Sep 24;63(6):889-901
references: 19778516
references: Proc Natl Acad Sci U S A. 2010 May 18;107(20):9388-93
references: 20439736
references: J Neurosci. 2012 Mar 28;32(13):4508-19
references: 22457498
references: Behav Brain Sci. 2009 Oct;32(5):429-48; discussion 448-494
references: 19857320
references: Front Hum Neurosci. 2011 Feb 17;5:11
references: 21369364
references: Cognition. 2002 Jul;84(3):295-320
references: 12044737
references: Science. 2009 May 29;324(5931):1160-4
references: 19478175
references: PLoS Comput Biol. 2012;8(7):e1002599
references: 22829759
references: J Neurosci. 2011 May 11;31(19):7102-10
references: 21562272
references: Brain Lang. 1999 Oct 15;70(1):29-69
references: 10534371
references: Front Hum Neurosci. 2012 Nov 22;6:310
references: 23189048
references: J Neurosci. 2012 Nov 7;32(45):16064-9
references: 23136442