title: Sleeve gastrectomy and gastroesophageal reflux disease.
abstract: Bariatric surgery, when combined with lifestyle and medical interventions, is a common and successful treatment modality in the obese patient. Laparoscopic sleeve gastrectomy is one such procedure that has increased in popularity as a definitive bariatric operation. Although laparoscopic sleeve gastrectomy has been shown to be effective in producing weight loss and improving type 2 diabetes mellitus, its effect on gastroesophageal reflux disease (GERD) has been inconsistent. This paper aims to summarize the available literature regarding GERD prevalence following laparoscopic sleeve gastrectomy, 8 studies demonstrate increased GERD prevalence, and 5 demonstrate decreased GERD prevalence following laparoscopic sleeve gastrectomy. The relationship between GERD and SG is complex and no clear relationship exists. The anatomic and physiologic changes caused by laparoscopic sleeve gastrectomy are discussed in the context of these inconsistent results.
authors: Department of Surgery, University of Alberta, Edmonton, AB, Canada.
authors: Michael
authors: M
authors: Laffin
authors: Johnny
authors: J
authors: Chau
authors: Richdeep S
authors: RS
authors: Gill
authors: Daniel W
authors: DW
authors: Birch
authors: Shahzeer
authors: S
authors: Karmali
mesh_terms: D050110:Bariatric Surgery / Q000009:adverse effects* / Q000379:methods; D005743:Gastrectomy / Q000009:adverse effects* / Q000379:methods; D005764:Gastroesophageal Reflux / Q000453:epidemiology*; D006801:Humans; D009767:Obesity, Morbid / Q000453:epidemiology / Q000601:surgery*; D015995:Prevalence; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D015431:Weight Loss
references: J Clin Invest. 1980 Feb;65(2):256-67
references: 7356677
references: Obes Surg. 2012 Dec;22(12):1874-9
references: 22915063
references: Obes Surg. 2007 Oct;17(10):1297-305
references: 18098398
references: Arch Intern Med. 2001 Jul 9;161(13):1581-6
references: 11434789
references: Obes Surg. 2010 Mar;20(3):357-62
references: 20013071
references: Ann Surg. 2010 Aug;252(2):319-24
references: 20622654
references: Am J Gastroenterol. 2002 Feb;97(2):241-8
references: 11866257
references: Aliment Pharmacol Ther. 2002 Apr;16(4):735-42
references: 11929391
references: Surg Endosc. 2012 Mar;26(3):831-7
references: 22179438
references: Am J Gastroenterol. 1996 Jun;91(6):1077-89
references: 8651151
references: Ann Surg. 2008 Mar;247(3):401-7
references: 18376181
references: J Gastrointest Surg. 2009 Aug;13(8):1440-7
references: 19475461
references: N Engl J Med. 1982 Dec 16;307(25):1547-52
references: 7144836
references: Obes Surg. 2007 Nov;17(11):1534-5
references: 18219786
references: Am J Gastroenterol. 2006 Aug;101(8):1900-20; quiz 1943
references: 16928254
references: Gut. 1995 Apr;36(4):505-10
references: 7737554
references: Cochrane Database Syst Rev. 2009 Apr 15;(2):CD003641
references: 19370590
references: Lancet. 2006 Jun 24;367(9528):2086-100
references: 16798392
references: Surg Obes Relat Dis. 2011 Jul-Aug;7(4):510-5
references: 21130052
references: Gastroenterology. 1995 Aug;109(2):601-10
references: 7615211
references: Surg Laparosc Endosc Percutan Tech. 2012 Dec;22(6):479-86
references: 23238373
references: Am J Physiol. 1989 Jan;256(1 Pt 1):G139-44
references: 2912145
references: Obes Surg. 2003 Feb;13(1):10-6
references: 12630607
references: Dig Dis Sci. 1988 Mar;33(3):270-5
references: 3342718
references: Ann Intern Med. 1993 Oct 1;119(7 Pt 2):655-60
references: 8363192
references: Obes Surg. 2006 Nov;16(11):1450-6
references: 17132410
references: Obes Surg. 2011 Mar;21(3):295-9
references: 21165778
references: Surg Obes Relat Dis. 2011 Sep-Oct;7(5):569-72
references: 21429818
references: Surg Obes Relat Dis. 2013 Jan-Feb;9(1):21-5
references: 23201209
references: Obes Surg. 2008 Sep;18(9):1083-8
references: 18535864
references: Ann Surg. 2013 Dec;258(6):976-82
references: 23160151
references: Obes Surg. 2009 May;19(5):565-70
references: 18855083
references: Ann Intern Med. 1992 Dec 15;117(12):977-82
references: 1443984
references: Surg Endosc. 2013 Apr;27(4):1260-6
references: 23232995
references: Obes Surg. 2008 Oct;18(10):1251-6
references: 18663545
references: Surg Obes Relat Dis. 2013 May-Jun;9(3):356-61
references: 22867558
references: Obes Surg. 2007 Jan;17(1):57-62
references: 17355769
references: Obes Surg. 2005 Aug;15(7):1024-9
references: 16105401
references: Surg Obes Relat Dis. 2010 Nov-Dec;6(6):707-13
references: 20947447
references: Annu Rev Public Health. 2001;22:355-75
references: 11274526
references: Obes Surg. 2008 Oct;18(10):1323-9
references: 18535867
references: Surg Obes Relat Dis. 2011 Nov-Dec;7(6):709-13
references: 21955743
references: Annu Rev Physiol. 2003;65:103-31
references: 12500969
references: JAMA. 1999 Oct 27;282(16):1523-9
references: 10546691
references: Obes Surg. 2008 May;18(5):560-5
references: 18317859
references: Obes Surg. 1998 Jun;8(3):267-82
references: 9678194
references: Obes Surg. 2010 Jan;20(1):1-6
references: 19802646
references: Surg Endosc. 2011 Jul;25(7):2323-9
references: 21298527
references: Obes Surg. 2009 Nov;19(11):1515-21
references: 19714384
references: Obes Surg. 2009 May;19(5):544-8
references: 19280267
references: N Engl J Med. 2012 Apr 26;366(17):1567-76
references: 22449319
references: Am J Physiol Gastrointest Liver Physiol. 2012 Jul;303(1):G42-53
references: 22517773
references: Surg Obes Relat Dis. 2010 Mar 4;6(2):152-7
references: 20189465
references: Arch Mal Appar Dig Mal Nutr. 1953 Jun;42(6):750-74
references: 13105424
references: Int J Cancer. 2006 Jan 15;118(2):458-66
references: 16049963
references: Obes Surg. 2007 Jul;17(7):962-9
references: 17894158
references: Am J Gastroenterol. 2013 Mar;108(3):308-28; quiz 329
references: 23419381
references: Gut. 1999 Apr;44(4):476-82
references: 10075953
references: J Gastrointest Surg. 2000 Jul-Aug;4(4):398-406
references: 11058858
references: Gastroenterology. 2007 Mar;132(3):883-9
references: 17324403
references: Am J Gastroenterol. 2007 May;102(5):1056-63
references: 17319930