title: Endonasal resection of early stage squamous cell carcinoma of the nasal vestibule.
abstract: The squamous cell carcinoma of the nasal vestibule (SCCNV) is a comparatively rare malignant disease. It occurs in the transition zone at the limen nasi. The choice of treatment for small tumors is a matter of controversy. Due to better cosmetic results, radiation therapy is usually recommended, however some recent reports have suggested that early stage tumors are equally or even more effectively managed by surgery. There was no standardized surgical procedure applied in these studies, though. The goal of our investigation was the retrospective evaluation of patients with a T1 or T2 carcinoma of the nasal vestibule who were treated surgically with an endonasal, endoscope-controlled approach at our ENT clinic between 2008 and 2010. Given the rarity of SCCNV, the 10 included cases represent the largest group of patients with early stage SCCNV treated primarily surgically by an endonasal approach so far. Our study shows that the endonasal resection of an early stage vestibular carcinoma seems adequate as a possible therapy. In the follow-up observation period no local or loco-regional recurrence was observed. The external cosmetic damage and endonasal scarring do not appear to be pronounced even following cartilage resection and were regarded as not seriously disadvantageous.
authors: Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University, Marchioninistr. 15, 81377, Munich, Germany, johannes_georg.ledderose@med.uni-muenchen.de.
authors: Georg J
authors: GJ
authors: Ledderose
authors: Simone
authors: S
authors: Reu
authors: Anna S
authors: AS
authors: Englhard
authors: Eike
authors: E
authors: Krause
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery*; D002356:Cartilage / Q000473:pathology / Q000601:surgery; D002921:Cicatrix / Q000175:diagnosis; D003131:Combined Modality Therapy; D004724:Endoscopy; D004954:Esthetics; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000473:pathology* / Q000601:surgery*; D009367:Neoplasm Staging; D009669:Nose Neoplasms / Q000473:pathology* / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed
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