title: New developments in the medical management of overactive bladder.
abstract: Overactive bladder (OAB) is a clinical syndrome describing the symptom complex of urgency, with or without urgency incontinence and is usually associated with frequency and nocturia. Whilst the majority of women will benefit from initial management with conservative and behavioural intervention a significant number will require medical therapy. Antimuscarinics are currently the most widely prescribed drugs for OAB although very often persistence with medication is limited due to lack of efficacy or intolerable adverse effects. The review, whilst giving a brief overview of OAB syndrome, will focus on new developments in drug therapy for OAB. In addition to evaluating new drugs with different methods of action it will also specifically focus on alternative modalities of treatment and how they may benefit patients with this troublesome and distressing condition.
authors: Department of Urogynaecology, Kings College Hospital, United Kingdom. Electronic address: dudley.robinson@nhs.net.
authors: Dudley
authors: D
authors: Robinson
authors: Ilias
authors: I
authors: Giarenis
authors: Linda
authors: L
authors: Cardozo
mesh_terms: D005260:Female; D006801:Humans; D007473:Ion Channels; D018377:Neurotransmitter Agents / Q000627:therapeutic use; D018167:Receptors, Calcitriol; D053201:Urinary Bladder, Overactive / Q000188:drug therapy*
chemical_list: D007473:Ion Channels; D018377:Neurotransmitter Agents; D018167:Receptors, Calcitriol
keywords: Antimuscarinics; Beta 3 agonists; Drug therapy; Overactive bladder