title: [Anxiogenic and depressogenic side-effects of non-psychiatric drugs].
abstract: Although medications such as anticancer, antimicrobial, immunomodulatory, neurological or hormonal therapies may have a negative impact on mood, adequate attention was not paid until the withdrawal of rimonabant in 2008. In the present study the authors review full spectrum of currently available medications discussing anxiety and depression as possible adverse effects of treatment. A relatively high risk of depression should always be considered when pharmacotherapy applied, especially if current depressive episodes, positive family history, or neurotic personality traits increasing susceptibility to depressogenic effects. Prior to start of medical treatment, the potential effectiveness of the given drug should be precisely evaluated, and alternative medical and non-medical treatment options should also be carefully considered. In addition, monitoring patients during treatment for signs of depressive or anxious symptoms is necessary.
authors: Semmelweis Egyetem, Gyógyszerésztudományi Kar Gyógyszerhatástani Intézet Budapest Nagyvárad tér 4. 1089.
authors: Eszter
authors: E
authors: Kirilly
authors: Xénia
authors: X
authors: Gonda
authors: Gabriella
authors: G
authors: Juhász
authors: György
authors: G
authors: Bagdy
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000009:adverse effects; D000890:Anti-Infective Agents / Q000009:adverse effects*; D019440:Anti-Obesity Agents / Q000009:adverse effects*; D000927:Anticonvulsants / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000978:Antiparkinson Agents / Q000009:adverse effects; D001007:Anxiety / Q000139:chemically induced*; D001008:Anxiety Disorders / Q000139:chemically induced; D002317:Cardiovascular Agents / Q000009:adverse effects*; D002491:Central Nervous System Agents / Q000008:administration & dosage / Q000009:adverse effects*; D003863:Depression / Q000139:chemically induced*; D003866:Depressive Disorder / Q000139:chemically induced; D003879:Dermatologic Agents / Q000009:adverse effects*; D005300:Fertility Agents, Female / Q000009:adverse effects*; D006801:Humans; D007155:Immunologic Factors / Q000009:adverse effects*; D016899:Interferon-beta / Q000009:adverse effects; D057285:Precision Medicine
chemical_list: D018712:Analgesics, Non-Narcotic; D000890:Anti-Infective Agents; D019440:Anti-Obesity Agents; D000927:Anticonvulsants; D000970:Antineoplastic Agents; D000978:Antiparkinson Agents; D002317:Cardiovascular Agents; D002491:Central Nervous System Agents; D003879:Dermatologic Agents; D005300:Fertility Agents, Female; D007155:Immunologic Factors; D016899:Interferon-beta