title: Interface haze associated with topical nonsteroidal anti-inflammatory drug use after descemet stripping automated endothelial keratoplasty.
abstract: OBJECTIVE
  To determine if topical nonsteroidal anti-inflammatory drug (NSAID) use after Descemet stripping automated endothelial keratoplasty (DSAEK) is associated with the development of interface haze.
  
  
  METHODS
  A retrospective case-control study of patients undergoing DSAEK surgery.
  
  
  RESULTS
  Of the 61 patients receiving topical NSAIDs, 51% were noted to develop interface haze, and 9% of the control group (N=100, no NSAID) developed haze. There was no significant difference in best corrected visual acuity between the 2 groups.
  
  
  CONCLUSIONS
  Topical NSAID use is associated with the development of interface haze, although it may not be visually significant and could be related to confounding factors.
authors: 1 Department of Ophthalmology, University of Oklahoma College of Medicine , Oklahoma City, Oklahoma.
authors: Sean
authors: S
authors: Paul
authors: Jeremy J
authors: JJ
authors: Bonkowske
authors: Donald U
authors: DU
authors: Stone
mesh_terms: D060433:Administration, Ophthalmic; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D016022:Case-Control Studies; D003315:Cornea / Q000473:pathology*; D057111:Descemet Stripping Endothelial Keratoplasty / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014792:Visual Acuity
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal