title: Chemical composition and biological activities of essential oils of Eremanthus erythropappus (DC) McLeisch (Asteraceae).
abstract: The chemical composition of the essential oils obtained by hydrodistillation of different parts of Eremanthus erythropappus, including leaves, branches and inflorescences, was investigated by Gas Chromatography and Gas Chromatography/Mass Spectrometry. The antimicrobial activity of the oils was assessed by the disc diffusion and microdilution methods, while the antioxidant activity was evaluated by DPPH and reducing power tests. The main compounds found in the essential oils derived from the inflorescences and leaves were β-caryophyllene, germacrene-D, α-copaene and β-pinene. α-Bisabolol was the major component in the branches. The oils were active against Staphylococcus aureus, Streptococcus pyogenes and fungi, but not Escherichia coli and Pseudomonas aeruginosa. The MIC values ranged from 0.01 to 0.50 mg/mL. Using the DPPH test, the IC50 values ranged from 38.77 ± 0.76 to 102.24 ± 1.96 μg/mL, while the reducing power test produced IC50 values between 109.85 ± 1.68 and 169.53 ± 0.64 μg/mL. The results revealed that the E. erythropappus oils are new promising potential sources of antimicrobial and antioxidant compounds with good future practical applications for human health.
authors: Department of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, São Pedro, Juiz de Fora, Minas Gerais 36036-330, Brazil.
authors: Marcelo S
authors: MS
authors: Silvério
authors: Glauciemar
authors: G
authors: Del-Vechio-Vieira
authors: Míriam A O
authors: MA
authors: Pinto
authors: Maria S
authors: MS
authors: Alves
authors: Orlando V
authors: OV
authors: Sousa
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry; D000975:Antioxidants / Q000737:chemistry; D019659:Asteraceae / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D000081222:Monocyclic Sesquiterpenes; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology; D000081223:Polycyclic Sesquiterpenes; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012717:Sesquiterpenes / Q000737:chemistry / Q000494:pharmacology; D045788:Sesquiterpenes, Germacrane / Q000737:chemistry; D013211:Staphylococcus aureus / Q000187:drug effects; D013297:Streptococcus pyogenes / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D000081222:Monocyclic Sesquiterpenes; D009822:Oils, Volatile; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; D045788:Sesquiterpenes, Germacrane; C004497:bisabolol; C024714:caryophyllene; C027259:germacrene D
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