title: Imidazolium salts and their polymeric materials for biological applications.
abstract: Imidazolium salts, distinct from their parent imidazoles, are made up of a discrete cation and anion pair, and have found widespread utility as ionic liquids. A lesser known function of such imidazolium salts includes the application of these salts in biological systems, and several areas of bio-applications, including antitumour, antimicrobial, antioxidant and bioengineering applications, will be presented and discussed in this review. The wide-ranging applications and versatility of these imidazolium salts stem from the ease of their structural variation, in which properties such as amphiphilicity, lipophilicity and solubility can be tuned.
authors: Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore. siti@ibn.a-star.edu.sg ygzhang@ibn.a-star.edu.sg.
authors: Siti Nurhanna
authors: SN
authors: Riduan
authors: Yugen
authors: Y
authors: Zhang
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001688:Biological Products / Q000737:chemistry; D015374:Biosensing Techniques; D002470:Cell Survival / Q000187:drug effects; D004337:Drug Carriers / Q000737:chemistry; D005658:Fungi / Q000187:drug effects; D007093:Imidazoles / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D011108:Polymers / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D000975:Antioxidants; D001688:Biological Products; D004337:Drug Carriers; D007093:Imidazoles; D011108:Polymers