title: Detection of influenza H7N9 virus: all molecular tests are not equal.
abstract: The recent emergence of influenza A virus (H7N9) emphasizes the need for its rapid detection. While commercial nucleic acid amplification tests (NAATs) are commonly used to detect seasonal influenza virus, this study demonstrated that the analytical sensitivity of commercial assays is highly variable compared to that of CDC-based in-house NAATs for the detection of H7N9.
authors: Division of Microbiology, Department of Pathology and Laboratory Medicine, Capital District Health Authority (CDHA), Halifax, Nova Scotia, Canada.
authors: Todd F
authors: TF
authors: Hatchette
authors: Steven J
authors: SJ
authors: Drews
authors: Nathalie
authors: N
authors: Bastien
authors: Yan
authors: Y
authors: Li
authors: Gregory
authors: G
authors: German
authors: Nick
authors: N
authors: Antonishyn
authors: Hugues
authors: H
authors: Charest
authors: Tony
authors: T
authors: Mazzulli
authors: Kevin
authors: K
authors: Fonseca
authors: Mel
authors: M
authors: Krajden
authors: Martin
authors: M
authors: Petric
authors: Kerry
authors: K
authors: Dust
authors: Jason J
authors: JJ
authors: LeBlanc
mesh_terms: D006801:Humans; D064766:Influenza A Virus, H7N9 Subtype / Q000235:genetics / Q000302:isolation & purification*; D007251:Influenza, Human / Q000175:diagnosis* / Q000821:virology*; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D012680:Sensitivity and Specificity; D014773:Virology / Q000379:methods*
references: N Engl J Med. 2013 May 16;368(20):1888-97
references: 23577628
references: Euro Surveill. 2013 May 23;18(21):
references: 23725980
references: J Clin Microbiol. 2013 Sep;51(9):3160-1
references: 23784125
references: J Clin Virol. 2009 Jul;45(3):200-2
references: 19515609
references: Can J Public Health. 2009 May-Jun;100(3):204-7
references: 19507723
references: J Clin Virol. 2007 Feb;38(2):169-71
references: 17194622
references: Crit Rev Clin Lab Sci. 2011 Sep-Dec;48(5-6):217-49
references: 22185616
references: J Clin Microbiol. 2006 Apr;44(4):1596-7
references: 16597906
references: Influenza Other Respir Viruses. 2009 Jul;3(4):171-6
references: 19627374
references: Euro Surveill. 2013 Apr 18;18(16):20461
references: 23611031
references: Influenza Other Respir Viruses. 2013 Jul;7(4):491-6
references: 22984843
references: J Clin Microbiol. 2009 Dec;47(12):3805-13
references: 19794033