title: Association between retinal venular dilation and serous retinal detachment in diabetic macular edema.
abstract: OBJECTIVE
  To study the relationship between retinal vessel diameter and qualitative and quantitative evaluations on spectral-domain optical coherence tomography in patients with diabetic macular edema.
  
  
  METHODS
  One hundred and eight consecutive eyes of 80 patients, with clinically significant macular edema underwent optical coherence tomography and color fundus photography. The authors evaluated the retinal thickness of the Early Treatment Diabetic Retinopathy Study grid and foveal pathomorphologies including cystoid macular edema and serous retinal detachment on the optical coherence tomography images. The diameters of the superotemporal or inferotemporal retinal vessels originating from the optic disk were measured using a computer-assisted technique.
  
  
  RESULTS
  The mean diameters of the superotemporal and inferotemporal venules were larger in eyes with diabetic macular edema than in healthy eyes. The mean diameter of the temporal venules but not the arterioles was associated with perifoveal thickening in the inferior subfield in eyes with diabetic macular edema (P = 0.014). Although the retinal thickening in the central subfield was not correlated with the diameters of the retinal vessels, eyes with foveal serous retinal detachment had larger mean diameters of superotemporal and inferotemporal venules than those without serous retinal detachment (P < 0.001).
  
  
  CONCLUSIONS
  The mean diameters of the superotemporal and inferotemporal venules were significantly associated with foveal serous retinal detachment in diabetic macular edema.
authors: *Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan; and †Nishijima Eye Clinic, Kyoto, Japan.
authors: Yuki
authors: Y
authors: Muraoka
authors: Tomoaki
authors: T
authors: Murakami
authors: Kazuaki
authors: K
authors: Nishijima
authors: Tadamichi
authors: T
authors: Akagi
authors: Akihito
authors: A
authors: Uji
authors: Takahiro
authors: T
authors: Horii
authors: Naoko
authors: N
authors: Ueda-Arakawa
authors: Munemitsu
authors: M
authors: Yoshikawa
authors: Akitaka
authors: A
authors: Tsujikawa
authors: Nagahisa
authors: N
authors: Yoshimura
mesh_terms: D000328:Adult; D000368:Aged; D003930:Diabetic Retinopathy / Q000150:complications*; D004108:Dilatation, Pathologic; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008269:Macular Edema / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D012169:Retinal Vein / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014699:Venules / Q000473:pathology