title: Granular cell tumour of tongue: A case report.
abstract: Granular cell tumour, also known as Abrikossoff tumour, is a relatively uncommon benign neoplasm, which is more commonly found in females in the 4th to 6th decades of life even though it can occur in all ages. It occurs in all areas of the body but about 45-65% of all lesions are reported in the head and neck region. Intraoral lesions represent about 70% of the granular cell tumours of the head and neck, and account for 1/3 of all cases affecting the whole body. Most of the intraoral lesions occur on the tongue, usually on the lateral aspect, followed by the buccal mucosa and hard palate. Although majority of granular cell tumours are benign, some are clinically aggressive and a few frankly malignant forms have been reported. Some benign lesions exhibit surface ulcerations and this clinical appearance, combined with the overlying pseudoepitheliomatous hyperplasia, seen histologically, may lead to misdiagnosis of malignancy if adequate biopsy material was not taken. A case of granular cell tumour which occurred on the midline area of the dorsum of the posterior 1/3 of the tongue is reported in a 20-year-old female patient. It is interesting because the patient was younger than the average age of occurrence and the tumour occurred in a similar site to that of a lingual thyroid.
authors: Department of Oral and Maxillofacial Surgery, Regional Dental Centre, King Khalid Hospital, P.O. Box 1120, Najran, Saudi Arabia.
authors: John Spencer M
authors: JS
authors: Daniels
keywords: Dorsum of posterior one-third of tongue; Granular cell tumour; Lingual thyroid; Pseudoepitheliomatous hyperplasia; Squamous cell carcinoma of tongue
references: Med Oral Patol Oral Cir Bucal. 2006 Aug 01;11(5):E425-8
references: 16878061
references: J Oral Surg. 1979 Jun;37(6):402-6
references: 220399
references: J Oral Maxillofac Surg. 1995 Jun;53(6):707-11
references: 7776058
references: Arch Otolaryngol Head Neck Surg. 1997 May;123(5):543-7
references: 9158404
references: Minerva Stomatol. 2004 Jul-Aug;53(7-8):465-9
references: 15278025
references: Pediatr Dermatol. 1987 Aug;4(2):94-7
references: 2821522
references: J Am Acad Dermatol. 1981 Aug;5(2):171-82
references: 6267110
references: J Natl Med Assoc. 1980 Dec;72(12):1171-5
references: 6273597
references: Med Oral Patol Oral Cir Bucal. 2006 Mar 01;11(2):E162-4
references: 16505796
references: J Oral Pathol Med. 1989 Jan;18(1):8-10
references: 2545872
references: Arch Surg. 1986 Aug;121(8):945-7
references: 3015070
references: J Surg Oncol. 1980;13(4):301-16
references: 6246310
references: Minerva Stomatol. 1996 May;45(5):231-7
references: 8783871
references: Int J Oral Maxillofac Surg. 1987 Apr;16(2):236-8
references: 3036969
references: J Pathol Bacteriol. 1956 Jan;71(1):85-94
references: 13307337
references: J Craniofac Surg. 2001 Jan;12(1):78-81
references: 11314193
references: Arch Anat Cytol Pathol. 1999;47(1):26-30
references: 10089680
references: J Oral Maxillofac Surg. 2000 Mar;58(3):345-8
references: 10716122
references: Am J Surg. 1979 Oct;138(4):611-4
references: 225962