title: Restless legs syndrome and akathisia as manifestations of acute pontine infarction.
abstract: Although restless legs syndrome (RLS) and akathisia have similar clinical manifestations and seem to share a common pathophysiology, they are regarded as distinct clinical syndromes. We present three patients with acute pontine infarction and RLS or akathisia as clinical manifestations. They presented with abrupt onset of restlessness of various body parts, as well as other neurological signs including dysarthria or weakness of the legs. Brain MRI of all three patients showed acute pontine infarction. The clinical syndrome in two of the patients was compatible with RLS and one with akathisia. Their symptoms improved after a brief period. Our finding of secondary RLS and akathisia as manifestations of acute pontine infarction provides information that assists in understanding the common anatomical and pathophysiological basis of RLS and akathisia.
authors: Department of Neurology, Chung-Ang University College of Medicine, 224-1, Heukseok-dong, Dongjak-gu, Seoul 156-755, South Korea.
authors: Su-Hyun
authors: SH
authors: Han
authors: Department of Neurology, Chung-Ang University College of Medicine, 224-1, Heukseok-dong, Dongjak-gu, Seoul 156-755, South Korea.
authors: Kwang-Yeol
authors: KY
authors: Park
authors: Department of Neurology, Chung-Ang University College of Medicine, 224-1, Heukseok-dong, Dongjak-gu, Seoul 156-755, South Korea.
authors: Young Chul
authors: YC
authors: Youn
authors: Department of Neurology, Chung-Ang University College of Medicine, 224-1, Heukseok-dong, Dongjak-gu, Seoul 156-755, South Korea. Electronic address: shinhw@cau.ac.kr.
authors: Hae-Won
authors: HW
authors: Shin
mesh_terms: D000368:Aged; D020526:Brain Stem Infarctions / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011149:Pons / Q000473:pathology; D011595:Psychomotor Agitation / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012148:Restless Legs Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
keywords: Akathisia; Pontine infarction; Restless legs syndrome