title: COPD updates: what's new in pathophysiology and management?
abstract: The historic perspective that used to define chronic obstructive pulmonary disease has changed. As reviewed in this article, it is based on a better understanding of the underlying inflammatory airflow obstruction and a multidimensional classification, which mostly targets a subgroup called 'frequent exacerbators'. Clinical and radioimaging predictors are the stamina for an aggressive therapeutic approach. A simplified explanation of the updated Global Initiative for Obstructive Lung Disease guidelines will ease the burden of treatment selection.
authors: Division of Pulmonary and Critical Care, Department of Internal Medicine, Tannourine Governmental Hospital, Batroun, Lebanon. carlosnjeim@hotmail.com
authors: Carlos
authors: C
authors: Noujeim
authors: Pierre
authors: P
authors: Bou-Khalil
mesh_terms: D018450:Disease Progression; D017079:Exercise Tolerance; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D018579:Patient Selection; D010641:Phenotype; D017410:Practice Guidelines as Topic; D011237:Predictive Value of Tests; D015995:Prevalence; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy*; D012129:Respiratory Function Tests; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D016896:Treatment Outcome