title: Distortion product otoacoustic emission level maps from normal and noise-damaged cochleae.
abstract: Distortion product otoacoustic emission (DPOAE) level mapping may be useful for detecting noise-induced hearing loss (NIHL) early. Employing DPOAE mapping effectively requires knowledge of the optimal mapping parameters to use for detecting noise-induced changes. The goal of this project was to show the map regions that differ most between normal and noise-damaged cochlea to determine the optimal mapping parameters for detecting NIHL. DPOAE level maps were generated for the 2f 1 -f 2 and the 2f 2 -f 1 DPOAEs for 17 normal hearing male subjects and 19 male subjects with NIHL. DPOAEs were measured in DPOAE frequency steps of approximately 44 Hz from 0.5 kHz to 6 kHz using constant f 2 /f 1 ratios incremented in 0.025 steps from 1.025 to 1.5 using both unequal-level (L1,L2 = 65,55 dB sound pressure level (SPL)) and equi-level (L1,L2 = 75,75 dB SPL) stimulus paradigms. Maximal responses for the 2f 2 -f 1 emission at L1,L2 = 65,55 dB SPL were found at lower ratios compared to previous studies. The map regions where NIHL eliminated or reduced DPOAE magnitude were identified. DPOAE level mapping using higher-level, equi-level primaries produced significantly more detectable emissions particularly for the 2f 2 -f 1 emission. The data from this study can be used to optimize DPOAE level mapping parameters for tracking noise-exposed subjects longitudinally.
authors: University of Northern Colorado, Greeley, CO 80639, USA. Deanna.Meinke@unco.edu
authors: Deanna K
authors: DK
authors: Meinke
authors: Odile H
authors: OH
authors: Clavier
authors: Jesse
authors: J
authors: Norris
authors: Robert
authors: R
authors: Kline-Schoder
authors: Lindsay
authors: L
authors: Allen
authors: Jay C
authors: JC
authors: Buckey
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D001301:Audiometry, Pure-Tone; D016022:Case-Control Studies; D003051:Cochlea / Q000503:physiopathology*; D006317:Hearing Loss, Noise-Induced / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*; D055815:Young Adult