title: Impact of different coils on biochemical T2 and T2* relaxation time mapping of articular patella cartilage.
abstract: OBJECTIVE
  The purpose of our study was to assess T2 and T2* relaxation time values of patella cartilage in healthy volunteers using three different coils at 3.0 Tesla MRI and their influence on the quantitative values.
  
  
  METHODS
  Fifteen volunteers were examined on the same 3-Tesla MR unit using three different coils: (i) a dedicated eight-channel knee phased-array coil; (ii) an eight-channel multi-purpose coil, and (iii) a one-channel 1H surface coil. T2 and T2* relaxation time measurements were prepared by a multi-echo spinecho respectively a gradient-echo sequence. A semi-automatic region-of-interest analysis was performed for patella cartilage. To allow stratification, a subregional analysis was carried out (deep-superficial cartilage layer). Statistical analysis-of-variance was performed.
  
  
  RESULTS
  The mean quantitative T2 values showed statistically significant differences in all comparison combinations. The differences between the mean quantitative T2* values were slightly less pronounced than the T2 evaluation and only the comparison between (i) and (ii) showed a significant difference. The results of T2 and T2* values showed, independent of the used coil, higher values in the superficial zone compared to the deep zone (p < 0.05). Looking at the signal alterations, all coils showed clearly higher values (and thus more signal alterations as a sign of noise) in the deep layer. The validation of the reliability showed a high intra-class correlation coefficient and hence a very high plausibility (ICC was between 0.870 and 0.905 for T2 mapping and between 0.879 and 0.888 for T2* mapping).
  
  
  CONCLUSIONS
  The present results demonstrate that biochemical T2 and T2* mapping is significantly dependent on the utilized coil.
authors: MR Center, Department of Radiology, Medical University of Vienna, Lazarettgasse 14, Vienna, Austria, milena.pachowsky@uk-erlangen.de.
authors: Milena L
authors: ML
authors: Pachowsky
authors: Siegfried
authors: S
authors: Trattnig
authors: Sebastian
authors: S
authors: Apprich
authors: Andreas
authors: A
authors: Mauerer
authors: Stephan
authors: S
authors: Zbyn
authors: Goetz H
authors: GH
authors: Welsch
mesh_terms: D000328:Adult; D002358:Cartilage, Articular / Q000033:anatomy & histology*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008280:Magnetics / Q000295:instrumentation*; D008297:Male; D010329:Patella / Q000033:anatomy & histology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014159:Transducers
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