title: The Association of Sleep Disorder, Obesity Status, and Diabetes Mellitus among US Adults-The NHANES 2009-2010 Survey Results.
abstract: To examine the association between sleep disorders, obesity status, and the risk of diabetes in adults, a total of 3668 individuals aged 40+ years from the NHANES 2009-2010 without missing information on sleep-related questions, measurements related to diabetes, and BMI were included in this analysis. Subjects were categorized into three sleep groups based on two sleep questions: (a) no sleep problems; (b) sleep disturbance; and (c) sleep disorder. Diabetes was defined as having one of a diagnosis from a physician; an overnight fasting glucose > 125 mg/dL; Glycohemoglobin > 6.4%; or an oral glucose tolerance test > 199 mg/dL. Overall, 19% of subjects were diabetics, 37% were obese, and 32% had either sleep disturbance or sleep disorder. Using multiple logistic regression models adjusting for covariates without including BMI, the odds ratios (OR, (95% CI)) of diabetes were 1.40 (1.06, 1.84) and 2.04 (1.40, 2.95) for those with sleep disturbance and with sleep disorder, respectively. When further adjusting for BMI, the ORs were similar for those with sleep disturbance 1.36 (1.06, 1.73) but greatly attenuated for those with sleep disorders (1.38 [0.95, 2.00]). In conclusion, the impact of sleep disorders on diabetes may be explained through the individuals' obesity status.
authors: Brock University, 500 Glenridge Avenue, St. Catharines, ON, Canada L2T 3A1.
authors: Jian
authors: J
authors: Liu
authors: John
authors: J
authors: Hay
authors: Brent E
authors: BE
authors: Faught
references: Sleep Breath. 2000;4(4):173-176
references: 11894204
references: N Engl J Med. 2011 Mar 17;364(11):987-9
references: 21410367
references: Ann N Y Acad Sci. 2008;1129:287-304
references: 18591489
references: J Appl Physiol (1985). 2005 Nov;99(5):2008-19
references: 16227462
references: Prev Med. 2007 Nov;45(5):348-52
references: 17889292
references: Diabetes Care. 2013 Jan;36 Suppl 1:S67-74
references: 23264425
references: Ann N Y Acad Sci. 2012 Aug;1264:110-34
references: 22827862
references: Am J Clin Nutr. 2002 Oct;76(4):743-9
references: 12324286
references: Eur Heart J. 2011 Jun;32(12):1484-92
references: 21300732
references: Diabetes Res Clin Pract. 2009 Nov;86(2):e34-6
references: 19631400
references: Sleep Breath. 2007 Sep;11(3):149-57
references: 17221274
references: Lancet. 2005 Mar 19-25;365(9464):1046-53
references: 15781100
references: Diabet Med. 2013 Jun;30(6):676-80
references: 23425048
references: BMJ Open. 2012 Aug 07;2(4):
references: 22872722
references: J Am Coll Cardiol. 2004 Feb 18;43(4):678-83
references: 14975482
references: Lancet. 1999 Oct 23;354(9188):1435-9
references: 10543671
references: Lipids Health Dis. 2011 Aug 23;10:148
references: 21861897
references: Int J Obes (Lond). 2013 Apr;37(4):552-8
references: 23419602
references: Diabetes Care. 2003 Feb;26(2):380-4
references: 12547866
references: Diabetes Care. 2005 Nov;28(11):2762-7
references: 16249553
references: BMJ. 2009 Jun 29;338:b2393
references: 19564179
references: Pediatrics. 2008 Feb;121(2):361-8
references: 18245428
references: Diabetes Care. 2012 Feb;35(2):313-8
references: 22210572
references: Diabetes Care. 2009 Jun;32(6):1017-9
references: 19279303
references: Epidemiol Rev. 2007;29:115-28
references: 17494056
references: Can J Public Health. 2011 Mar-Apr;102(2):139-43
references: 21608387
references: Diabetes. 1988 Dec;37(12):1595-607
references: 3056758
references: Diabetes Care. 2013 Mar;36(3):611-7
references: 23150286
references: Front Biosci (Elite Ed). 2012 Jan 01;4:2007-21
references: 22202016
references: Intern Med. 2011;50(21):2499-502
references: 22041348
references: Sleep. 2000 Feb 1;23(1):71-9
references: 10678467
references: Diabetes Care. 2005 Nov;28(11):2739-44
references: 16249549