title: The impact of physical and psychological comorbid conditions on the quality of life of patients with acute myocardial infarction: a multi-center, cross-sectional observational study from Turkey.
abstract: OBJECTIVE
  Acute myocardial infarction (MI) has significant and detrimental effects on the lifestyles of the patients. It has been shown that quality of life (QoL) in patients with MI is impaired in every aspect. This study aims to evaluate the impact of depression and physical comorbidity on QoL in Turkish patients with acute first MI.
  
  
  METHODS
  This multi-center cross-sectional study was carried out in 15 centers with 998 patients hospitalized for acute first MI. For detection of depression, Beck Depression Inventory (BDI) was used. For evaluation of QoL, World Health Organization Quality of Life Questionnaire (WHOQOL) was applied.
  
  
  RESULTS
  The mean age of the patients was 57.5 +/- 10.1 years and 79.2 % (n = 792) of the patients were men. Patients with comorbid depression (BDI > or = 10) and comorbid medical conditions, and female patients had significantly lower scores in every domain of WHOQOL. In the regression analysis model, female gender, low education, comorbid medical conditions, especially comorbid hypertension, and BDI score were found to have a significant effect on the domains of WHOQOL.
  
  
  CONCLUSIONS
  Female patients are more prone to impairment in quality of life after myocardial infarction. Both comorbid medical conditions and depression have a significant impact on the impairment of QoL in Turkish patients with acute MI. In order to improve the subjective wellbeing of post MI patients, both psychiatric and physical comorbidities must be detected and managed even in the short-term.
authors: Department of Psychiatry, School of Medicine, Ege University, Izmir, Turkey. onensertoz@gmail.com
authors: O Onen
authors: OO
authors: Sertoz
authors: O
authors: O
authors: Aydemir
authors: D
authors: D
authors: Gulpek
authors: H
authors: H
authors: Elbi
authors: Y
authors: Y
authors: Ozenli
authors: A
authors: A
authors: Yilmaz
authors: E
authors: E
authors: Ozan
authors: F
authors: F
authors: Atesci
authors: E
authors: E
authors: Abay
authors: M
authors: M
authors: Semiz
authors: N
authors: N
authors: Direk
authors: C
authors: C
authors: Hocaoglu
authors: Z
authors: Z
authors: Elyas
authors: M
authors: M
authors: Ozmen
authors: S
authors: S
authors: Ozen
authors: N
authors: N
authors: Konuk
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease / Q000523:psychology*; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000523:psychology*; D010555:Personality Inventory / Q000706:statistics & numerical data; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology*; D011795:Surveys and Questionnaires; D014421:Turkey