title: Mycobacterium kansasii septicaemia in an AIDS patient complicated by acute respiratory distress syndrome and acute liver failure.
abstract: Acute respiratory distress syndrome (ARDS) is a serious complication of sepsis. Only a few cases of non-tuberculous mycobacteria complicated by ARDS have been discussed in the literature to date. Mycobacterium kansasii is the most pathogenic non-tuberculous mycobacterium affecting the lung. In the late stages of acquired immunodeficiency syndrome (AIDS), it may also present as disseminated disease. The clinical course is usually chronic, and the time to clinical diagnosis can sometimes be long, requiring a careful and meticulous search for the pathogen. To our knowledge, this is the first case report of disseminated M. kansasii infection complicated by ARDS and acute liver failure in a patient with end-stage AIDS.
authors: Department of Infectious Diseases, Hematology and Oncology, St Michael's Medical Center, Newark, USA.
authors: Hamid
authors: H
authors: Shaaban
authors: Trevor
authors: T
authors: Layne
authors: John W
authors: JW
authors: Sensakovic
authors: Jack
authors: J
authors: Boghossian
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D017114:Liver Failure, Acute / Q000150:complications* / Q000188:drug therapy; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D019909:Mycobacterium kansasii / Q000187:drug effects / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D012128:Respiratory Distress Syndrome / Q000150:complications*; D018805:Sepsis / Q000150:complications* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000995:Antitubercular Agents
keywords: AIDS; ARDS; HIV; Mycobacterium kansasii; North America; acute respiratory distress syndrome; disseminated infection; liver failure; lung; non-tuberculous mycobacteria; pulmonary; septicaemia; viral disease