title: Dipyrone (metamizole) can nullify the antiplatelet effect of aspirin in patients with coronary artery disease.
authors: University Hospital Düsseldorf, Medical Faculty, Division of Cardiology, Pulmonology, and Vascular Medicine, Heinrich Heine University Medical Center Düsseldorf, Düsseldorf, Germany. Electronic address: amin.polzin@med.uni-duesseldorf.de.
authors: Amin
authors: A
authors: Polzin
authors: University Hospital Düsseldorf, Medical Faculty, Division of Cardiology, Pulmonology, and Vascular Medicine, Heinrich Heine University Medical Center Düsseldorf, Düsseldorf, Germany.
authors: Tobias
authors: T
authors: Zeus
authors: Institute for Pharmacology and Clinical Pharmacology, Heinrich Heine University, Düsseldorf, Germany.
authors: Karsten
authors: K
authors: Schrör
authors: University Hospital Düsseldorf, Medical Faculty, Division of Cardiology, Pulmonology, and Vascular Medicine, Heinrich Heine University Medical Center Düsseldorf, Düsseldorf, Germany.
authors: Malte
authors: M
authors: Kelm
authors: Institute for Pharmacology and Clinical Pharmacology, Heinrich Heine University, Düsseldorf, Germany.
authors: Thomas
authors: T
authors: Hohlfeld
mesh_terms: D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D001241:Aspirin / Q000627:therapeutic use*; D003324:Coronary Artery Disease / Q000188:drug therapy*; D004177:Dipyrone / Q000009:adverse effects*; D004347:Drug Interactions; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D013931:Thromboxanes / Q000096:biosynthesis
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D010975:Platelet Aggregation Inhibitors; D013931:Thromboxanes; D004177:Dipyrone; D001241:Aspirin
keywords: aspirin; coronary artery disease; dipyrone; high treatment-platelet reactivity; metamizole; nonresponder