title: Association between aortic calcification and the risk of osteoporosis in a chinese cohort: the Chongqing osteoporosis study.
abstract: The aim of this study was to examine the relationship between aortic calcification (AC) and the risk of osteoporosis for a community of residents in China. We conducted a 5-year prospective study on 1,729 Chinese elderly subjects. An AC scale (ACS) was determined semiquantitatively from baseline lateral radiographs of the lumbar spine. Dual-energy X-ray absorptiometry was used to determine bone mineral density (BMD). Only subjects who completed the study were included in the final analysis; 432 subjects (25.0 %) developed osteoporosis. The BMD of vertebrae, femoral neck, and the total hip in the Q4 quartile of the ACS (ACS > 6) was lower when compared with the Q1 quartile (ACS = 0, p < 0.05). Cox proportional hazards model analysis showed that ACS (Q4), BMD, CTX, current smoking, and daily drinking were associated with increased risk of osteoporosis. A higher ACS was associated with an increased risk of osteoporosis in both women and men. The present study found that AC carried a higher risk of osteoporosis.
authors: Department of Orthopedics, The Orthopedic Surgery Center of Chinese PLA, Southwest Hospital, Third Military Medical University, Chongqing, 400038, People's Republic of China, zhourui519@foxmail.com.
authors: Rui
authors: R
authors: Zhou
authors: Huadong
authors: H
authors: Zhou
authors: Min
authors: M
authors: Cui
authors: Yanjiang
authors: Y
authors: Wang
authors: Jun
authors: J
authors: Tan
authors: Darrell
authors: D
authors: Sawmiller
authors: Jianzhong
authors: J
authors: Xu
mesh_terms: D000368:Aged; D001018:Aortic Diseases / Q000150:complications* / Q000453:epidemiology*; D044466:Asian People / Q000706:statistics & numerical data; D015519:Bone Density; D002947:Cities / Q000706:statistics & numerical data; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000453:epidemiology* / Q000209:etiology*; D012307:Risk Factors; D061205:Vascular Calcification / Q000150:complications* / Q000453:epidemiology*