title: Helicobacter pylori infection in Nigerians with dyspepsia.
abstract: BACKGROUND
  Helicobacter pylori is the most common chronic bacterial infection, and a significant aetiological factor in acid peptic diseases and gastric cancer. Dyspepsia is a common gastrointestinal disorder, and the most common indication for gastroscopy. Detection of this organism during endoscopy has become standard clinical practice. We determine the prevalence of H. pylori infection among dyspeptic patients using serology and histology.
  
  
  METHODS
  Patients with dyspepsia underwent gastroscopy, and biopsies were taken from the antral portions of their stomach and processed. Their serum samples were tested for H. pylori infection using ELISA to detect anti-bodies.
  
  
  RESULTS
  One hundred and twenty-five patients, comprising 49 (39.2%) males and 76 (60.8%) females were studied. A prevalence rate of 93.6% for H. pylori was found by serology while a rate of 80.0% was found by histology.
  
  
  CONCLUSIONS
  There is a high prevalence of H. pylori infection in patients with dyspepsia; and a high percentage of detection by serological and histological tests.
authors: Department Of Medicine, University Of Ilorin, Ilorin, Kwara 240001, Nigeria. drabolokoba@yahoo.com
authors: A B
authors: AB
authors: Olokoba
authors: W
authors: W
authors: Gashau
authors: S
authors: S
authors: Bwala
authors: A
authors: A
authors: Adamu
authors: F K
authors: FK
authors: Salawu
mesh_terms: D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D001706:Biopsy; D004415:Dyspepsia / Q000453:epidemiology / Q000382:microbiology*; D016099:Endoscopy, Gastrointestinal; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000453:epidemiology* / Q000473:pathology; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence; D013270:Stomach / Q000473:pathology; D055815:Young Adult
chemical_list: D000907:Antibodies, Bacterial
keywords: Helicobacter pylori; Nigerians; dyspepsia; histology; serology
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