title: HLA in Georgians (Caucasus) and their relationship with Eastern Mediterraneans.
abstract: HLA-A, -B, -DQB1, and -DRB1 typing has been performed in a sample of Georgian population (South Caucasus). Allele frequencies, neighbour joining and correspondence relatedness analyses and extended HLA haplotypes have been obtained with comparison with other Middle East and Mediterranean populations. Our Georgian sample tends to be genetically related in these analyses with Eastern Mediterraneans and Middle East people. This is important for future regional transplant programs, and Georgian HLA and disease epidemiology and pharmacogenomics.
authors: Diego
authors: D
authors: Rey
authors: Cristina
authors: C
authors: Areces
authors: Javier
authors: J
authors: Alonso-Rubio
authors: Mercedes
authors: M
authors: Enríquez-de-Salamanca
authors: Sedeka
authors: S
authors: Abd-El-Fatah-Khalil
authors: Nina
authors: N
authors: Bendikuze
authors: Mercedes
authors: M
authors: Fernández-Honrado
authors: Luz
authors: L
authors: Barbolla
authors: José Manuel
authors: JM
authors: Martín-Villa
authors: Antonio
authors: A
authors: Arnaiz-Villena
mesh_terms: D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency / Q000235:genetics; D005828:Genetics, Population; D005843:Geography; D005846:Georgia (Republic); D006680:HLA Antigens / Q000235:genetics*; D015234:HLA-A Antigens / Q000235:genetics; D059866:HLA-DQ beta-Chains / Q000235:genetics; D059811:HLA-DRB1 Chains / Q000235:genetics; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D007802:Language; D015810:Linkage Disequilibrium / Q000235:genetics; D019083:Mediterranean Region; D010802:Phylogeny
chemical_list: D006680:HLA Antigens; D015234:HLA-A Antigens; D059866:HLA-DQ beta-Chains; D059811:HLA-DRB1 Chains
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