title: Effects of the organic acids produced by a lactic acid bacterium in Apis mellifera colony development, Nosema ceranae control and fumagillin efficiency.
abstract: The European honey bee Apis mellifera is known to be affected by many parasites and pathogens that have great impact over the insect development. Among parasites affecting bee health, Nosema ceranae is one of the main biotic factors affecting colony populations. As honey bee populations decline, interest in pathogenic and mutualistic relationships between bees and microorganisms has increased. The main goal of the current study was to assess the effect of the oral administration of the metabolites produced by Lactobacillus johnsonii CRL1647 (mainly organic acids) supplemented in syrup, on: (I) N. ceranae sporulation dynamics before and after fumagillin application, and (II) performance of A. mellifera colonies. Different experiments were conducted to evaluate the effects of these bacterial metabolites on bees: in vitro administration revealed no toxic effects against bees. Colonies fed with the lactic acids incremented their beehive population and also the amount of fat bodies per bee. Finally, the organic acids reduced the intensity of the pathogen after the second application of treatment as well as enhanced the fumagillin efficiency. This study provides important information for the development of new control substances against nosemosis.
authors: Laboratorio de Artrópodos, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata, 7600 Mar del Plata, Argentina; CONICET, Consejo Nacional de Investigaciones Científicas y Técnicas, Rivadavia 1917, C1033AJ Buenos Aires, Argentina. Electronic address: biomaggi@gmail.com.
authors: Matías
authors: M
authors: Maggi
authors: Pedro
authors: P
authors: Negri
authors: Santiago
authors: S
authors: Plischuk
authors: Nicolás
authors: N
authors: Szawarski
authors: Fiorella
authors: F
authors: De Piano
authors: Leonardo
authors: L
authors: De Feudis
authors: Martín
authors: M
authors: Eguaras
authors: Carina
authors: C
authors: Audisio
mesh_terms: D000143:Acids / Q000494:pharmacology*; D000704:Analysis of Variance; D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology / Q000633:toxicity; D001516:Bees / Q000187:drug effects / Q000382:microbiology*; D003510:Cyclohexanes / Q000494:pharmacology* / Q000633:toxicity; D005216:Fat Body / Q000187:drug effects; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology* / Q000633:toxicity; D007778:Lactobacillus / Q000737:chemistry* / Q000378:metabolism; D016818:Nosema / Q000187:drug effects* / Q000502:physiology*; D010572:Pest Control, Biological; D012717:Sesquiterpenes / Q000494:pharmacology / Q000633:toxicity
chemical_list: D000143:Acids; D000935:Antifungal Agents; D003510:Cyclohexanes; D005231:Fatty Acids, Unsaturated; D012717:Sesquiterpenes; C026211:fumagillin
keywords: Apis mellifera; Bacterial metabolites; Fumagillin; Nosema ceranae control; Organic acids