title: Superior mesenteric artery syndrome and its associated gastrointestinal implications.
abstract: The superior mesenteric artery (SMA) syndrome is a rare but potentially life-threatening gastrointestinal condition. Over the years, it has been referenced by several names, the most common of which is Wilkie's syndrome. These numerous terminologies have made it difficult to estimate its true frequency in the general population. Common symptoms associated with this syndrome include intermittent postprandial abdominal pain, nausea, and bilious vomiting. Our review revealed that although it is currently well-defined in the literature, the diagnosis of SMA syndrome remains challenging as other disorders can mimic its presentation. However, CT angiography is currently favored in the literature for diagnosis as it can not only show the narrowed aorto-mesenteric angle and distance, but also the extent of duodenal obstruction. In addition, we found no consensus on the preferred mode of therapy once SMA syndrome is diagnosed. The agreement among authors is that the treatment options should be based on severity of the disease, using conservative measures as the first line of therapy in mild SMA syndrome. Duodenojejunostomy is the preferred surgical approach when conservative management fails, or in severe cases.
authors: Department of Anatomical Sciences, School of Medicine, St. George's University, Grenada, West Indies.
authors: Njambi
authors: N
authors: Mathenge
authors: Stephen
authors: S
authors: Osiro
authors: Iliana I
authors: II
authors: Rodriguez
authors: Christian
authors: C
authors: Salib
authors: R Shane
authors: RS
authors: Tubbs
authors: Marios
authors: M
authors: Loukas
mesh_terms: D000792:Angiography; D004380:Duodenal Obstruction / Q000175:diagnosis; D004385:Duodenostomy; D004386:Duodenum / Q000000981:diagnostic imaging* / Q000196:embryology; D006801:Humans; D007582:Jejunostomy; D017538:Mesenteric Artery, Superior / Q000000981:diagnostic imaging* / Q000196:embryology; D013478:Superior Mesenteric Artery Syndrome / Q000175:diagnosis* / Q000196:embryology / Q000628:therapy; D014057:Tomography, X-Ray Computed
keywords: CT angiography; SMA syndrome; duodenal compression; duodenojejunostomy; gastrointestinal emergency