title: An optical deoxyribonucleic acid-based half-subtractor.
abstract: This study introduces an optical DNA-based logic circuit that mimics a half-subtractor. The system contains an Au-surface immobilized molecular-beacon molecule that serves as a dual-gate molecule and outputs two series of fluorescence signals following Boolean INH and XOR patterns after interacting with one or two single-stranded DNA molecules as input. To the best of our knowledge, the system reported herein is rather concise compared to other molecular logic gate systems.
authors: Institute of Biotechnology, National University of Kaohsiung, Kaohsiung, Taiwan. cnyang@nuk.edu.tw.
authors: Chia-Ning
authors: CN
authors: Yang
authors: Yi-Li
authors: YL
authors: Chen
authors: Hung-Yin
authors: HY
authors: Lin
authors: Chun-Yu
authors: CY
authors: Hsu
mesh_terms: D001483:Base Sequence; D002232:Carbocyanines / Q000737:chemistry; D039301:Computers, Molecular; D004247:DNA / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry*; D019793:Fluorescein / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*
chemical_list: D002232:Carbocyanines; D004277:DNA, Single-Stranded; D005456:Fluorescent Dyes; C085321:cyanine dye 5; D006046:Gold; D004247:DNA; D019793:Fluorescein