title: Consequence of the antioxidant activities and tyrosinase inhibitory effects of various extracts from the fruiting bodies of Pleurotus ferulae.
abstract: This study was initiated to screen the antioxidant activities, tyrosinase inhibitory effects on the fruiting bodies of Pleurotus ferulae extracted with acetone, methanol and hot water. The antioxidant activities were performed on β-carotene-linoleic acid, reducing power, DPPH, ferrous ions chelating abilities, and xanthine oxidase. In addition to this, phenolic compounds were also analyzed. The methanolic extract showed the strongest β-carotene-linoleic acid inhibition and high reducing power as compared to other extracts. The scavenging effects on DPPH radicals, the acetonic and methanolic extracts were more effective than hot water extracts. The strongest chelating effect was obtained from the methanolic extract as compared to the tested synthetic antioxidant. Gallic acid, protocatechuic acid, caffeic acid, vanillin, ferulic acid, naringin, resveratrol, naringenin, hesperetin, formononetin and biochanin-A were detected from acetonitrile and hydrochloric acid (5:1) solvent extract. Xanthine oxidase and tyrosinase inhibitory activities of acetonic, methanolic, and hot water extracts of P. ferulae increased with increasing concentration. The results suggested that consumption of P. ferulae might be beneficial to the antioxidant, xanthine oxidase, and tyrosinase protection system of the human body against oxidative damage and others complications.
authors: Division of Life Sciences, University of Incheon, Incheon 406-840, Republic of Korea.
authors: Nuhu
authors: N
authors: Alam
authors: Ki Nam
authors: KN
authors: Yoon
authors: Jae Seong
authors: JS
authors: Lee
authors: Hae Jin
authors: HJ
authors: Cho
authors: Tae Soo
authors: TS
authors: Lee
keywords: Antioxidant; Phenolic compounds; Pleurotus ferulae; Tyrosinase inhibition; Xanthine oxidase
references: J Agric Food Chem. 2008 Aug 27;56(16):7265-70
references: 18616260
references: Biosci Biotechnol Biochem. 2005 Jan;69(1):197-201
references: 15665485
references: Crit Rev Food Sci Nutr. 1992;32(1):67-103
references: 1290586
references: Environ Microbiol. 2008 May;10(5):1145-57
references: 18218030
references: Molecules. 2011 Mar 10;16(3):2334-47
references: 21394078
references: Biochem J. 1984 Apr 1;219(1):1-14
references: 6326753
references: Planta Med. 2001 Mar;67(2):158-61
references: 11301865
references: Planta Med. 1992 Aug;58(4):342-4
references: 1332092
references: J Ethnopharmacol. 2008 Oct 28;119(3):507-12
references: 18573327
references: J Ethnopharmacol. 1999 Feb;64(2):149-60
references: 10197750
references: Mutat Res. 1988 Dec;202(2):377-86
references: 3057368
references: Microbiology (Reading). 2001 Jul;147(Pt 7):1755-1763
references: 11429453
references: J Ethnopharmacol. 2003 May;86(1):51-8
references: 12686441
references: Arch Biochem Biophys. 1994 Nov 15;315(1):161-9
references: 7979394
references: J Agric Food Chem. 2003 Apr 9;51(8):2168-73
references: 12670151
references: Mycobiology. 2010 Dec;38(4):295-301
references: 23956669