title: A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients.
abstract: OBJECTIVE
  Complex sleep behaviors (CSBs) are classified as "parasomnias" in the International Classifcation of Sleep Disorders, Second Edition (ICSD-2). To realize the potential danger after taking two short-acting Z-hypnosedative drugs, we estimated the incidence of CSBs in nonpsychotic patients in Taiwan.
  
  
  METHODS
  Subjects (N = 1,220) using zolpidem or zopiclone were enrolled from the psychiatric outpatient clinics of a medical center in Taiwan over a 16-month period in 2006-2007. Subjects with zolpidem (N = 1,132) and subjects with zopiclone (N = 88) were analyzed. All subjects completed a questionnaire that included demographic data and complex sleep behaviors after taking hypnotics.
  
  
  RESULTS
  Among zolpidem and zopiclone users, 3.28% of patients reported incidents of somnambulism or amnesic sleep-related behavior problems. The incidence of CSBs with zolpidem and zopiclone were 3.27%, and 3.41%, respectively, which was signifcantly lower than other studies in Taiwan.
  
  
  CONCLUSIONS
  These results serve as a reminder for clinicians to make inquiries regarding any unusual performance of parasomnic activities when prescribing zolpidem or zopiclone.
authors: Department of Psychiatry, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei City, Taiwan.
authors: Li-Fen
authors: LF
authors: Chen
authors: Ching-En
authors: CE
authors: Lin
authors: Yu-Ching
authors: YC
authors: Chou
authors: Wei-Chung
authors: WC
authors: Mao
authors: Yi-Chyan
authors: YC
authors: Chen
authors: Nian-Sheng
authors: NS
authors: Tzeng
keywords: amnesic sleep-related behavior; parasomnia; sleepwalking; somnambulism; zolpidem; zopiclone
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