title: Clarithromycin-induced haemorrhagic colitis.
abstract: Haemorrhagic colitis by Klebsiella oxytoca has been described as an antibiotic-associated colitis, particularly with the use of ampicillin. Here we report a patient with haemorrhagic colitis caused by K oxytoca after the use of clarithromycin. A 67-year-old Japanese woman with diabetes presented with mucobloody diarrhoea and abdominal pain. Stool culture grew K oxytoca. Colonoscopy showed the appearance of haemorrhagic colitis. Further history taking revealed that she had received a course of oral clarithromycin for upper respiratory tract infection. She had recovered by conservative treatment. We should be careful about gastrointestinal symptoms in patients on clarithromycin, which can cause haemorrhagic colitis associated with K oxytoca.
authors: Department of General Internal Medicine, Mito Kyodo General Hospital, University of Tsukuba, Mito, Ibaraki, Japan.
authors: Ryosuke
authors: R
authors: Miyauchi
authors: Kensuke
authors: K
authors: Kinoshita
authors: Yasuharu
authors: Y
authors: Tokuda
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D017291:Clarithromycin / Q000009:adverse effects*; D003092:Colitis / Q000139:chemically induced* / Q000382:microbiology; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced*; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy; D041121:Klebsiella oxytoca
chemical_list: D000900:Anti-Bacterial Agents; D017291:Clarithromycin
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