title: Nevirapine-induced rash with eosinophilia and systemic symptoms (DRESS).
abstract: Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is an adverse reaction commonly occurring with antiepileptic agents. It was earlier referred to by various names such as dilantin hypersensitivity syndrome and anticonvulsant hypersensitivity syndrome. It is characterized by the triad of fever, skin eruption, and systemic involvement. DRESS syndrome has also been reported with a number of other drugs including allopurinol, minocycline, terbinafine, sulfonamides, azathioprine, dapsone, and antiretroviral agents such as abacavir and nevirapine. We describe a rare case of nevirapine-induced hypersensitivity syndrome that was successfully treated with oral steroids.
authors.affiliation: Department of Internal Medicine, Armed Forces Medical College, Pune, Maharashtra, India.
authors.forename: Shaman
authors.initials: S
authors.lastname: Gill
authors.forename: Amitabh
authors.initials: A
authors.lastname: Sagar
authors.forename: S
authors.initials: S
authors.lastname: Shankar
authors.forename: Velu
authors.initials: V
authors.lastname: Nair
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D004802:Eosinophilia / Q000139:chemically induced*; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D008297:Male; D019829:Nevirapine / Q000009:adverse effects*
chemical_list: D019380:Anti-HIV Agents; D019829:Nevirapine
keywords: Drug reaction with eosinophilia and systemic symptoms syndrome; drug rash; hypersensitivity; nevirapine