title: Vertical ridge augmentation with a collagen membrane, bovine bone mineral and fibrin sealer: clinical and histologic findings.
abstract: This study evaluated the treatment of alveolar bone deficiencies combined with dental implant placement. Thirty-five endosseous implants were inserted into 20 patients. After implant placement, the mean height of the supracrestal bone defects measured 4.25 ± 1.34 mm. Bone regeneration procedures were performed using a combination of a bovine bone-derived mineral stabilized with a fibrin-fibronectin sealing system and covered with a bilayered porcine collagen membrane. Healing was uneventful in all instances with maintenance of primary closure throughout the healing period. Stage-two surgery was performed after 6 months, and a hard bonelike tissue was detectable at the defect sites. Histologic examination confirmed the presence of newly formed bone with residual particles of xenograft. The mean bone gain was 3.95 ± 1.47 mm. The positive outcomes in terms of bone regeneration and low complication rate demonstrated the potential of this technique for the treatment of supracrestal ridge deficiencies. Bovine bone mineral combined with a fibrin sealer and protected by a collagen membrane should be considered as an alternative in the treatment of vertical peri-implant bone defects.
authors.affiliation: PROED Institute for Professional Education in Dentistry, Torino, Italy. dacardar@tin.it
authors.forename: Daniele
authors.initials: D
authors.lastname: Cardaropoli
authors.forename: Lorena
authors.initials: L
authors.lastname: Gaveglio
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Cardaropoli
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016301:Alveolar Bone Loss / Q000601:surgery*; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D000818:Animals; D001861:Bone Regeneration; D016025:Bone Transplantation / Q000379:methods*; D002417:Cattle; D003094:Collagen; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D005260:Female; D015718:Fibrin Tissue Adhesive; D006801:Humans; D007576:Jaw, Edentulous, Partially / Q000601:surgery; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D013552:Swine; D016896:Treatment Outcome; D014716:Vertical Dimension
chemical_list: D015921:Dental Implants; D015718:Fibrin Tissue Adhesive; D008567:Membranes, Artificial; D003094:Collagen