title: [A case of mucinous adenocarcinoma of the sigmoid colon with disseminated carcinomatosis of the bone marrow successfully treated with FOLFOX4/bevacizumab].
abstract: A 68-year-old man complaining of back pain was given the diagnosis of mucinous adenocarcinoma of the sigmoid colon with disseminated carcinomatosis of bone marrow and disseminated intravascular coagulation(DIC). We started chemotherapy using FOLFOX4. After we confirmed that DIC had improved following 2 courses of FOLFOX4, bevacizumab was added to FOLFOX4. Laboratory studies revealed a serum CEA level of 11, 432 ng/mL, which improved to 245 ng/mL after a total of 9 courses of chemotherapy. Chemotherapy is continuing as scheduled at 6 months from the onset of this disease.
authors.affiliation: Dept. of Gastroenterology, Chuno Kosei Hospital.
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamazaki
authors.forename: Naoki
authors.initials: N
authors.lastname: Katsumura
authors.forename: Noritaka
authors.initials: N
authors.lastname: Ozawa
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Ogiso
authors.forename: Yoriko
authors.initials: Y
authors.lastname: Hanai
authors.forename: Kentaro
authors.initials: K
authors.lastname: Otsuji
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Toda
authors.forename: Kotaro
authors.initials: K
authors.lastname: Morino
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Mori
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Araki
authors.forename: Hisataka
authors.initials: H
authors.lastname: Moriwaki
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000188:drug therapy* / Q000556:secondary; D000368:Aged; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D000068258:Bevacizumab; D019046:Bone Marrow Neoplasms / Q000188:drug therapy* / Q000556:secondary; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D012811:Sigmoid Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D009944:Organoplatinum Compounds; D000068258:Bevacizumab; D002955:Leucovorin; D005472:Fluorouracil