title: A rhodamine-based fluorescent probe for detecting Hg(2+) in a fully aqueous environment.
abstract: A water-soluble fluorescent probe for Hg(2+) based on a rhodamine B derivative was designed and synthesized. The new probe showed reversible colorimetric and fluorescent response to Hg(2+) in a fully aqueous solution. The probe exhibited real-time detection of Hg(2+) with high selectivity in media containing less than 1% organic cosolvent. Furthermore, bioimaging studies indicated that the new probe was cell permeable and suitable for the real-time imaging of Hg(2+) in living cells by confocal microscopy.
authors.affiliation: Department of Chemistry, Anhui University, Hefei 230039, P. R. China. mengxm@ahu.edu.cn fy70@163.com.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Chen
authors.forename: Xiangming
authors.initials: X
authors.lastname: Meng
authors.forename: Shuxing
authors.initials: S
authors.lastname: Wang
authors.forename: Yulei
authors.initials: Y
authors.lastname: Cai
authors.forename: Yifan
authors.initials: Y
authors.lastname: Wu
authors.forename: Yan
authors.initials: Y
authors.lastname: Feng
authors.forename: Manzhou
authors.initials: M
authors.lastname: Zhu
authors.forename: Qingxiang
authors.initials: Q
authors.lastname: Guo
mesh_terms: D002470:Cell Survival; D003124:Colorimetry; D018360:Crystallography, X-Ray; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008628:Mercury / Q000032:analysis*; D008958:Models, Molecular; D015394:Molecular Structure; D012235:Rhodamines / Q000138:chemical synthesis / Q000737:chemistry*; D012995:Solubility; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D014867:Water / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D012235:Rhodamines; D014867:Water; D008628:Mercury; C029773:rhodamine B