title: Preparation of carboxylic acid-bearing polysaccharide nanofiber made from euglenoid β-1,3-glucans.
abstract: This paper introduces a new strategy for creating surface modified polysaccharide nanofibers. To demonstrate proof of principle, the synthesis, structure, and self-assembly behavior of a carboxylic acid-bearing polysaccharide made from paramylon (β-1,3-glucan) and succinic anhydride were investigated. Examination by a combination of NMR, FT-IR, and SEC-MALLS confirmed that successful preparation of the desired succinylated paramylon without significant depolymerization. NMR, SEC-MALLS, visible absorption and CD spectroscopic analyses indicated that the paramylon derivative forms the triplex structure in solutions. SEM observation revealed that succinylated paramylon forms a nanofiber that has carboxylic acid on the surface.
authors.affiliation: Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 6th, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan. moto.shibakami@aist.go.jp
authors.forename: Motonari
authors.initials: M
authors.lastname: Shibakami
authors.forename: Gen
authors.initials: G
authors.lastname: Tsubouchi
authors.forename: Makoto
authors.initials: M
authors.lastname: Nakamura
authors.forename: Masahiro
authors.initials: M
authors.lastname: Hayashi
mesh_terms: D002236:Carbohydrate Conformation; D002264:Carboxylic Acids / Q000737:chemistry*; D005055:Euglena / Q000737:chemistry*; D005240:Feasibility Studies; D005936:Glucans / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D055595:Mechanical Phenomena; D008970:Molecular Weight; D057139:Nanofibers / Q000737:chemistry*; D019802:Succinic Acid / Q000737:chemistry; D013499:Surface Properties; D013696:Temperature
chemical_list: D002264:Carboxylic Acids; D005936:Glucans; C003045:paramylon; D019802:Succinic Acid
keywords: Carboxylic acid; Euglena; Nanofiber; Paramylon; β-1,3-glucan