title: [Secondary osteoporosis or secondary contributors to bone loss in fracture. Vitamin D deficiency and fracture].
abstract: Vitamin D plays an important role in maintaining bone and calcium metabolism. Vitamin D deficiency causes not only low bone mineral density via secondary hyperparathyroidism, but also impairment of bone mineralization. Vitamin D deficiency also increases the risk of fall. Thus, vitamin D deficiency results in increased fracture risk. Serum 25 (OH) D level reflects Vitamin D store and more than 30 ng/mL is recommended for bone health, but the measurement of serum 25 (OH) D is not reimbursed by Japanese health insurance system. Vitamin D supplementation to vitamin D deficient osteoporotics reduces the fracture incidence by both increasing bone mineral density and reducing falls. Evaluation of vitamin D status and its adequate supplementation are prerequisite for proper osteoporosis management.
authors.affiliation: Third Department of Medicine, Teikyo University Chiba Medical Center, Japan.
authors.forename: Reiko
authors.initials: R
authors.lastname: Watanabe
authors.forename: Ryo
authors.initials: R
authors.lastname: Okazaki
mesh_terms: D000818:Animals; D015519:Bone Density; D019587:Dietary Supplements; D050723:Fractures, Bone / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D010024:Osteoporosis / Q000209:etiology* / Q000378:metabolism; D014807:Vitamin D / Q000378:metabolism; D014808:Vitamin D Deficiency / Q000150:complications*
chemical_list: D014807:Vitamin D