title: [Influence of Schinus terebinthifolius Raddi (aroeira) and Carapa guianensis Aublet (andiroba) in the healing process of gastrorraphies].
abstract: BACKGROUND
  The gastrorraphy isolated or associated with the use of biological adhesives formed throughout the history of surgery the usual way to promote healing in gastric lesions; however, the use of herbal medicine has been increasingly employed to help the wound healing.
  
  
  OBJECTIVE
  To evaluate the wound healing caused in the stomach of rats using extract of Schinus terebinthifolius Raddi and Carapa guianensis Aublet oil.
  
  
  METHODS
  Ninety rats, adult males were divided into three groups: aroeira, andiroba and control group, which were subdivided into three subgroups of five animals according to the time of the deaths (seven, 14 and 21 days). All underwent the same surgical procedure (injury and suture the stomach) differing only to the animals in groups aroeira and andiroba that received a daily dose of 100 mg / kg of hydroalcoholic extract and oil, by gavage, while the control group received normal saline. The parameters evaluated were the macroscopic and microscopic test of resistance to air insufflation and test the traction force.
  
  
  RESULTS
  All animals showed good healing of gastric and abdominal wall without infection and dehiscence. Both groups presented neighboring organs adhesions on the gastric surface. The endurance test for air insufflation showed higher average pressure within seven days and the test revealed greater traction force of rupture between seven and 14 days in groups aroeira and andiroba. The intensity of chronic inflammation revealed statistically significant differences in angiogenesis and fibroblast proliferation.
  
  
  CONCLUSIONS
  The use of extract of Schinus terebinthifolius Raddi and Carapa guianensis Aublet oil favored the gastric wound healing in rats.
authors.affiliation: Departmento de Medicina II, Universidade Federal do Maranhão, Campus do Bacanga, São Luís, MA, Brasil. 　orlanddojs@hotmail.com
authors.forename: Orlando José Dos
authors.initials: OJ
authors.lastname: Santos
authors.forename: Osvaldo
authors.initials: O
authors.lastname: Malafaia
authors.forename: Jurandir Marcondes
authors.initials: JM
authors.lastname: Ribas-Filho
authors.forename: Nicolau Gregori
authors.initials: NG
authors.lastname: Czeczko
authors.forename: Rayan Haquim Pinheiro
authors.initials: RH
authors.lastname: Santos
authors.forename: Rennan Abud Pinheiro
authors.initials: RA
authors.lastname: Santos
mesh_terms: D027926:Anacardiaceae; D000818:Animals; D008297:Male; D029582:Meliaceae; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D013270:Stomach / Q000601:surgery*; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D010936:Plant Extracts