title: Reuse of a previously transplanted kidney: does success come with a price?
abstract: Longer wait times for deceased donor kidney transplant have prompted newer initiatives to expedite the process. Reuse of a previously transplanted kidney might be appropriate in certain circumstances. However, one must also consider the unique issues that may arise after such transplants. We describe our experience in one such case where the donor kidney had lesions of focal and segmental glomerulosclerosis and signs of alloreactivity (positive C4d staining) prior to transplantation and the recipient developed ganciclovir-resistant cytomegalovirus (CMV) infection, which was perhaps transmitted from the donor. Despite the challenges, the allograft function remained stable 5 years after reuse.
authors.affiliation: Division of Nephrology and Hypertension, Department of Medicine , University of Texas Medical Branch , Galveston, TX , USA.
authors.forename: Pradeep V
authors.initials: PV
authors.lastname: Kadambi
authors.forename: W James
authors.initials: WJ
authors.lastname: Chon
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Josephson
authors.forename: Amishi
authors.initials: A
authors.lastname: Desai
authors.forename: J Richard
authors.initials: JR
authors.lastname: Thistlethwaite
authors.forename: Robert C
authors.initials: RC
authors.lastname: Harland
authors.forename: Shane M
authors.initials: SM
authors.lastname: Meehan
authors.forename: Marc R
authors.initials: MR
authors.lastname: Garfinkel
keywords: cytomegalovirus (CMV); ganciclovir resistance; organ reuse; rejection