title: Amide I Band and Photoinduced Disassembly of a Peptide Hydrogel.
abstract: Peptide hydrogels are promising candidates for a wide range of medical and biotechnological applications. To further expand the potential utility of peptide hydrogels, herein we demonstrate a simple yet effective strategy to render peptide hydrogels photodegradable, making controlled disassembly of the gel structure of interest feasible. In addition, we find that the high-frequency amide I' component (i.e., the peak at ~1685 cm-1) of the photodegradable peptide hydrogel studied shows an unusually large enhancement, in comparison to that of other peptide fibrils consisting of antiparallel β-sheets, making it a good model system for further study of the coupling-structure relationship.
authors.affiliation: Department of Chemistry, University of Pennsylvania, 231 South 34 Street, Philadelphia, PA 19104, USA.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Measey
authors.forename: Beatrice N
authors.initials: BN
authors.lastname: Markiewicz
authors.forename: Feng
authors.initials: F
authors.lastname: Gai