title: Anthracene-bisphosphonate based novel fluorescent organic nanoparticles explored as apoptosis inducers of cancer cells.
abstract: We report the first synthesis and use of a well defined fluorescent organic nanoparticle (FON), tetraethyl anthracene-9,10-diyl-9,10-bis(phosphonate) [TEABP], as a selective anticancer candidate by apoptosis mediated cancer therapy towards U937 cells together with its unique solvatochromic properties.
authors.affiliation: Department of Materials Science, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India. msab@iacs.res.in.
authors.forename: Malay
authors.initials: M
authors.lastname: Pramanik
authors.forename: Nabanita
authors.initials: N
authors.lastname: Chatterjee
authors.forename: Subhadip
authors.initials: S
authors.lastname: Das
authors.forename: Krishna Das
authors.initials: KD
authors.lastname: Saha
authors.forename: Asim
authors.initials: A
authors.lastname: Bhaumik
mesh_terms: D000873:Anthracenes / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects*; D004164:Diphosphonates / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D005456:Fluorescent Dyes / Q000737:chemistry; D006801:Humans; D018613:Microscopy, Confocal; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry*; D009369:Neoplasms / Q000188:drug therapy; D020298:U937 Cells
chemical_list: D000873:Anthracenes; D000970:Antineoplastic Agents; D004164:Diphosphonates; D005456:Fluorescent Dyes; C587916:tetraethyl anthracene-9,10-diyl-9,10-bis(phosphonate); C034020:anthracene