title: In vivo antiplaque effect of three edible toothpastes.
abstract: OBJECTIVE
  The objective of this study was to analyse the antibacterial and antiplaque activity of three edible toothpastes with the widest worldwide distribution: KidScents™, which contains essential oils; Browning B& B™, with medicinal plants; and Wysong Probiodent™, which contains probiotics.
  
  
  METHODS
  The study group was formed of twenty healthy volunteers (dental students) with a good oral health status. Using a balanced randomisation system, all volunteers performed toothbrushing with four products (the three edible toothpastes and water) at intervals of one week. Bacterial vitality in the saliva was analysed by epifluorescence microscopy and plaque regrowth was evaluated using the Turesky-Quigley-Hein plaque index.
  
  
  RESULTS
  Bacterial vitality in the saliva was significantly higher after toothbrushing with water (positive control) than with the three toothpastes (P=0.002, P=0.003 and P<0.001, respectively). The plaque index was significantly higher after using these three toothpastes than after toothbrushing with water (P=0.047, P=0.032 and P<0.001, respectively).
  
  
  CONCLUSIONS
  The three edible toothpastes analysed have some antimicrobial activity but favour plaque regrowth.
authors.affiliation: c/ Entrerríos sn, 15782 Santiago de Compostela, Spain, susana.rubido@usc.es.
authors.forename: Susana
authors.initials: S
authors.lastname: Rubido
authors.forename: Javier
authors.initials: J
authors.lastname: Fernández-Feijoo
authors.forename: Jacobo
authors.initials: J
authors.lastname: Limeres
authors.forename: Lucía
authors.initials: L
authors.lastname: García-Caballero
authors.forename: María-Teresa
authors.initials: MT
authors.lastname: Abeleira
authors.forename: Pedro
authors.initials: P
authors.lastname: Diz
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003773:Dental Plaque / Q000517:prevention & control*; D006801:Humans; D009822:Oils, Volatile / Q000008:administration & dosage; D010936:Plant Extracts / Q000008:administration & dosage; D019936:Probiotics / Q000008:administration & dosage; D014100:Toothpastes
chemical_list: D000900:Anti-Bacterial Agents; D009822:Oils, Volatile; D010936:Plant Extracts; D014100:Toothpastes