title: Low-dose CT scan screening for lung cancer: comparison of images and radiation doses between low-dose CT and follow-up standard diagnostic CT.
abstract: OBJECTIVE
  This study aim to compare image quality and radiation doses between low-dose CT and follow-up standard diagnostic CT for lung cancer screening.
  
  
  METHODS
  In a single medical institution, 19 subjects who had been screened for lung cancer by low-dose CT before going through follow-up standard diagnostic CT were randomly selected. Both CT image sets for all subjects were independently evaluated by five specialized physicians.
  
  
  RESULTS
  There were no significant differences between low-dose CT screening and follow-up standard diagnostic CT for lung cancer screening in all 11 criteria. The concordance rate for the diagnoses was approximately 80% (p < 0.001) for all categories. Agreement of the evaluation of all categories in the final diagnosis exceeded 94% (p < 0.001). Five physicians detecting and characterizing the pulmonary nodules did not recognized the difference between low-dose CT screening and follow-up standard diagnostic CT. With low-dose CT, the effective dose ranged between 1.3 and 3.4 mSv, whereas in the follow-up diagnostic CT, the effective dose ranged between 8.5 and 14.0 mSv.
  
  
  CONCLUSIONS
  This study suggests that low-dose CT can be effectively used as a follow-up standard diagnostic CT in place of standard-dose CT in order to reduce the radiation dose.
authors.affiliation: Faculty of Nursing at Higashigaoka, Tokyo Healthcare University, 2-5-1, Higashigaoka, Meguro, Tokyo, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Ono
authors.forename: Toru
authors.initials: T
authors.lastname: Hiraoka
authors.forename: Asami
authors.initials: A
authors.lastname: Ono
authors.forename: Eiji
authors.initials: E
authors.lastname: Komatsu
authors.forename: Takehiko
authors.initials: T
authors.lastname: Shigenaga
authors.forename: Hajime
authors.initials: H
authors.lastname: Takaki
authors.forename: Toru
authors.initials: T
authors.lastname: Maeda
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ogusu
authors.forename: Shintaro
authors.initials: S
authors.lastname: Yoshida
authors.forename: Kiyoyasu
authors.initials: K
authors.lastname: Fukushima
authors.forename: Michiaki
authors.initials: M
authors.lastname: Kai
keywords: ImPACT; Llow-dose; Lung cancer; Screening CT; WAZA-ARI