title: Comparison of child morbidity in regions of Ostrava, Czech Republic, with different degrees of pollution: a retrospective cohort study.
abstract: BACKGROUND
  To confirm or refute the hypothesis that the morbidity of children (since birth to age 5) born and living in the heavily polluted (PM10, benzo[a]pyrene) eastern part of Ostrava, Czech Republic, was higher than the morbidity of children living in other parts of the city.
  
  
  METHODS
  Ten pediatricians in 5 districts of Ostrava abstracted the medical records of 1878 children born in 2001-2004 to list all illnesses of each child in ICD-10 codes. The children were divided into four groups according to their residence at birth and thereafter. Most of the children in the eastern area were living in the city district Radvanice and Bartovice.
  
  
  RESULTS
  We report on the incidence of acute illnesses in 1535 children of Czech ethnicity in the first 5 years of life. The most frequent acute illnesses (over 45% of all diagnoses) were upper respiratory infections (URI: J00-J02, J06). In the first year of life, the incidence of URI in 183 children in the eastern area - 372 illnesses/100 children/year - was more than twice as high as in the other 3 areas with a total number of 1352 children. From birth to the age of 5 years, the incidences of pneumonia, tonsillitis, viral infections (ICD-10 code B34) and intestinal infectious diseases were also several times higher in children living in the eastern part of Ostrava. The lowest morbidity was found in children living in the less polluted western part of the city.
  
  
  CONCLUSIONS
  The children born and living in the eastern part of the city of Ostrava had from birth through 5 years significantly higher incidence rates of acute illnesses than children in other parts of Ostrava. They also had a higher prevalence of wheezing, atopic dermatitis and allergic rhinitis.
authors.affiliation: Institute of Experimental Medicine AS CR, Prague, Czech Republic. dostal@biomed.cas.cz.
authors.forename: Miroslav
authors.initials: M
authors.lastname: Dostal
authors.forename: Anna
authors.initials: A
authors.lastname: Pastorkova
authors.forename: Stepan
authors.initials: S
authors.lastname: Rychlik
authors.forename: Eva
authors.initials: E
authors.lastname: Rychlikova
authors.forename: Vlasta
authors.initials: V
authors.lastname: Svecova
authors.forename: Eva
authors.initials: E
authors.lastname: Schallerova
authors.forename: Radim J
authors.initials: RJ
authors.lastname: Sram
mesh_terms: D000393:Air Pollutants / Q000633:toxicity*; D000397:Air Pollution; D002675:Child, Preschool; D015331:Cohort Studies; D018153:Czech Republic / Q000453:epidemiology; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007410:Intestinal Diseases / Q000139:chemically induced / Q000453:epidemiology*; D008297:Male; D009017:Morbidity; D010033:Otitis Media / Q000139:chemically induced / Q000453:epidemiology*; D015995:Prevalence; D012140:Respiratory Tract Diseases / Q000139:chemically induced / Q000453:epidemiology*; D012189:Retrospective Studies; D014777:Virus Diseases / Q000139:chemically induced / Q000453:epidemiology*
chemical_list: D000393:Air Pollutants