title: Chemical Constituents of Gymnopilus spectabilis and Their Antioxidant Activity.
abstract: Gymnopilus spectabilis, a hallucinogenic mushroom belonging to the family Cortinariaceae, is found growing in dense clusters on stumps and logs of hardwoods and conifers. It contains the hallucinogenic alkaloid psilocybin and its strongly bitter taste makes it undesirable as an edible. In an effort to identify chemical constituents of Korean native wild mushrooms, 4,6-decadiyne-1,3,8-triol (1), ergosta-4,6,8(14), 22-tetraen-3-one (2), bisnoryangonin (3), and hispidin (4) were isolated from the methanolic extract of the fruiting bodies of G. spectabilis. Their structures were assigned on the basis of various spectroscopic studies. Compounds 3 and 4 displayed significant scavenging activity against the ABTS radical cation, DPPH radical, and superoxide radical anion, while 1 and 2 exhibited no antioxidant activity.
authors.affiliation: Korea Research Institute of Bioscience and Biotechnology (KRIBB), 111 Gwahangno, Yuseong-gu, Daejeon 305-806, Korea.
authors.forename: In-Kyoung
authors.initials: IK
authors.lastname: Lee
authors.forename: Sung-Min
authors.initials: SM
authors.lastname: Cho
authors.forename: Soon-Ja
authors.initials: SJ
authors.lastname: Seok
authors.forename: Bong-Sik
authors.initials: BS
authors.lastname: Yun
keywords: 4,6-Decadiyne-1,3,8-triol; Antioxidant; Bisnoryangonin; Ergosta-4,6,8,22-tetraen-3-one; Gymnopilus spectabilis; Hispidin