title: Synthetic biological networks.
abstract: Despite their obvious relationship and overlap, the field of physics is blessed with many insightful laws, while such laws are sadly absent in biology. Here we aim to discuss how the rise of a more recent field known as synthetic biology may allow us to more directly test hypotheses regarding the possible design principles of natural biological networks and systems. In particular, this review focuses on synthetic gene regulatory networks engineered to perform specific functions or exhibit particular dynamic behaviors. Advances in synthetic biology may set the stage to uncover the relationship of potential biological principles to those developed in physics.
authors.affiliation: Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Eric
authors.initials: E
authors.lastname: Archer
authors.forename: Gürol M
authors.initials: GM
authors.lastname: Süel
mesh_terms: D000818:Animals; D058045:Artificial Cells / Q000737:chemistry* / Q000378:metabolism*; D053263:Gene Regulatory Networks / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D015398:Signal Transduction / Q000502:physiology*; D058615:Synthetic Biology / Q000379:methods*