title: Vitreo-retinal interface changes on optical coherence tomography in the fellow eyes of patients with macular hole.
abstract: OBJECTIVE
  To study the vitreo-retinal interface and macular changes on optical coherence tomography (OCT) in the fellow eyes of patients with macular hole.
  
  
  METHODS
  Patients with idiopathic macular hole in one or both eyes presented to our institute between January 2003 and December 2009 were evaluated retrospectively. Demographic details, best-corrected visual acuity and vitreo-retinal interface, and macular changes of the fellow eye on OCT were studied.
  
  
  RESULTS
  Seventy patients underwent OCT of both eyes during the study period. The average age group was 61.96 years and 35 (50%) were females. Among the fellow eyes, normal foveal contour was noted in 36 (51.4%) eyes and 34 (48.6%) eyes were observed to have vitreo-retinal interface changes. Of them, 13 (18.6%) eyes had some stage of full thickness macular hole and 21 (30.0%) eyes had interface changes. There was no statistical correlation between involved eye lesions (P=0.64) or visual acuity (P=0.55) as predictors of development of either fellow eye lesions or poor visual acuity.
  
  
  CONCLUSIONS
  There is a significant chance of having vitreo-retinal interface findings in the fellow eyes of patients presenting with macular hole. OCT should be considered in both eyes of patients with macular hole to detect early changes in the fellow eyes, which may require an early intervention.
authors.affiliation: Smt. Kanuri Santhamma Retina Vitreous Centre, L.V. Prasad Eye Institute, Kallam Anji Reddy Campus, L.V. Prasad Marg, Banjara Hills, Hyderabad 500034, India.
authors.forename: Ajit Babu
authors.initials: AB
authors.lastname: Majji
authors.forename: Jay Kumar
authors.initials: JK
authors.lastname: Chhablani
authors.forename: Bupesh
authors.initials: B
authors.lastname: Bagga
keywords: fellow eye; macular hole; optical coherence tomography; vitreo-retinal interface