title: [Oral status and oral mucosa blood circulation changes in patients with chronic heart failure].
abstract: The objective of this study was to characterize dental status and oral mucosa blood flow in patients with chronic heart failure and amyloid deposits in oral mucosa. Histological and immunohistochemical analysis of 80 oral mucosa biopsies taken from patients aged 32-72 years with chronic heart failure I-IV NYHA functional class was carried out. It detected a systemic amyloidosis in 15.7% of cases; a local amyloid deposition in oral mucosa was found in 58.5% of cases. Amyloid deposition in oral mucosa was associated with severe chronic generalized periodontitis in more than a half of cases. Amyloid deposits in oral mucosa were revealed more often in patients with metabolic syndrome (63.5%). The article describes dental status and oral mucosa blood flow in patients with heart failure.
authors.forename: L Iu
authors.initials: LIu
authors.lastname: Orekhova
authors.forename: M G
authors.initials: MG
authors.lastname: Rybakova
authors.forename: A A
authors.initials: AA
authors.lastname: Barmasheva
authors.forename: I A
authors.initials: IA
authors.lastname: Kuznetsova
authors.forename: E N
authors.initials: EN
authors.lastname: Semernin
authors.forename: N A
authors.initials: NA
authors.lastname: Shirshova
authors.forename: E V
authors.initials: EV
authors.lastname: Shliakhto
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Gudkova
mesh_terms: D000328:Adult; D000368:Aged; D000686:Amyloidosis / Q000150:complications / Q000473:pathology; D001775:Blood Circulation; D001783:Blood Flow Velocity; D002908:Chronic Disease; D005260:Female; D006333:Heart Failure / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000098:blood supply* / Q000473:pathology*; D009909:Oral Health; D010518:Periodontitis / Q000150:complications / Q000473:pathology; D018616:Ultrasonography, Doppler, Duplex