title: [The comparative investigation of antihypoxia activity of glutamic and N-acetylglutamic acids].
abstract: Comparative study of antihypoxic activity of glutamic and N-acetylglutamic acid in doses of 1, 10, 50 and 100 mg/kg was realized. It was experimentally ascertained that the most apparent antihypoxic action of study objects occurs in conditions of hypobaric hypoxia of acetylated derivative of glutamic acid considerably exceeds glutamic acid.
authors.forename: L M
authors.initials: LM
authors.lastname: Makarova
authors.forename: V E
authors.initials: VE
authors.lastname: Pogorelyĭ
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D005971:Glutamates / Q000494:pharmacology*; D018698:Glutamic Acid / Q000494:pharmacology*; D006935:Hypercapnia / Q000503:physiopathology / Q000517:prevention & control*; D000860:Hypoxia / Q000503:physiopathology / Q000517:prevention & control*; D007274:Injections, Intraperitoneal; D008136:Longevity / Q000187:drug effects*; D051379:Mice; D008808:Mice, Inbred CBA; D009599:Nitroprusside / Q000494:pharmacology; D012977:Sodium Nitrite / Q000494:pharmacology
chemical_list: D005971:Glutamates; D009599:Nitroprusside; D018698:Glutamic Acid; D012977:Sodium Nitrite; C016195:N-acetylglutamic acid