title: MRA versus DSA for follow-up of coiled intracranial aneurysms: a meta-analysis.
abstract: MR angiography is proposed as a safer and less expensive alternative to the reference standard, DSA, in the follow-up of intracranial aneurysms treated with endovascular coil occlusion. We performed a systematic review and meta-analysis to evaluate the accuracy of TOF-MRA and contrast-enhanced MRA in detecting residual flow in the follow-up of coiled intracranial aneurysms. Literature was reviewed through the PubMed, Cochrane, and EMBASE data bases. In comparison with DSA, the sensitivity of TOF-MRA was 86% (95% CI: 82-89%), with a specificity of 84% (95% CI: 81-88%), for the detection of any recurrent flow. For contrast-enhanced MRA, the sensitivity and specificity were 86% (95% CI: 82-89%) and 89% (95% CI: 85-92%), respectively. Both TOF-MRA and contrast-enhanced MRA are shown to be highly accurate for detection of any recanalization in intracranial aneurysms treated with endovascular coil occlusion.
authors.affiliation: From the Departments of Neurosurgery (M.J.v.A., H.D.B., J.d.V., R.H.M.A.B.).
authors.forename: M J
authors.initials: MJ
authors.lastname: van Amerongen
authors.affiliation: From the Departments of Neurosurgery (M.J.v.A., H.D.B., J.d.V., R.H.M.A.B.) h.boogaarts@nch.umcn.nl.
authors.forename: H D
authors.initials: HD
authors.lastname: Boogaarts
authors.affiliation: From the Departments of Neurosurgery (M.J.v.A., H.D.B., J.d.V., R.H.M.A.B.).
authors.forename: J
authors.initials: J
authors.lastname: de Vries
authors.affiliation: Epidemiology and Biostatistics (A.L.M.V.).
authors.forename: A L M
authors.initials: AL
authors.lastname: Verbeek
authors.affiliation: Radiology/Neuroradiology (F.J.A.M., M.P.), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
authors.forename: F J A
authors.initials: FJ
authors.lastname: Meijer
authors.affiliation: Radiology/Neuroradiology (F.J.A.M., M.P.), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: Prokop
authors.affiliation: From the Departments of Neurosurgery (M.J.v.A., H.D.B., J.d.V., R.H.M.A.B.).
authors.forename: R H M A
authors.initials: RH
authors.lastname: Bartels
mesh_terms: D015901:Angiography, Digital Subtraction / Q000379:methods*; D004621:Embolization, Therapeutic / Q000295:instrumentation / Q000379:methods; D057510:Endovascular Procedures / Q000295:instrumentation / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging* / Q000628:therapy; D018810:Magnetic Resonance Angiography / Q000379:methods*