title: Degradation study of enniatins by liquid chromatography-triple quadrupole linear ion trap mass spectrometry.
abstract: Enniatins A, A1, B and B1 (ENs) are mycotoxins produced by Fusarium spp. and are normal contaminants of cereals and derivate products. In this study, the stability of ENs was evaluated during food processing by simulation of pasta cooking. Thermal treatments at different incubation times (5, 10 and 15 min) and different pH (4, 7 and 10) were applied in an aqueous system and pasta resembling system (PRS). The concentrations of the targeted mycotoxins were determined using liquid chromatography coupled to tandem mass spectrometry. High percentages of ENs reduction (81-100%) were evidenced in the PRS after the treatments at 5, 10 and 15 min of incubation. In contrast to the PRS, an important reduction of the ENs was obtained in the aqueous system after 15 min of incubation (82-100%). In general, no significant differences were observed between acid, neutral and basic solutions. Finally, several ENs degradation products were identified using the technique of liquid chromatography-triple quadrupole linear ion trap mass spectrometry.
authors.affiliation: Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Spain.
authors.forename: A B
authors.initials: AB
authors.lastname: Serrano
authors.forename: G
authors.initials: G
authors.lastname: Meca
authors.forename: G
authors.initials: G
authors.lastname: Font
authors.forename: E
authors.initials: E
authors.lastname: Ferrer
mesh_terms: D002851:Chromatography, High Pressure Liquid; D047630:Depsipeptides / Q000737:chemistry*; D006358:Hot Temperature; D013058:Mass Spectrometry; D015394:Molecular Structure; D009183:Mycotoxins / Q000737:chemistry*; D014908:Triticum / Q000737:chemistry*
chemical_list: D047630:Depsipeptides; D009183:Mycotoxins; C100264:enniatins
keywords: Degradation products; Enniatins; LC–MS-LIT; LC–MS/MS; Reduction; Thermal treatments