title: [Evaluation of implanted cardioverter-defibrillators for primary prevention of sudden cardiac death].
abstract: OBJECTIVE
  To evaluate the clinical effect of implanted cardioverter-defibrillators (ICD) for primary prevention of sudden cardiac death.
  
  
  METHODS
  According to ACC/AHA Guideline of ICD implantation (2005), 35 patients successfully received ICD/CRT-D implantation for primary prevention of sudden cardiac death in our hospital from January 2006 to December 2009. All the patients were followed up for a mean of 2 years.
  
  
  RESULTS
  During the follow up, 11 (31.43%) patients experienced ventricular arrhythmic episodes, for which 16 defibrillation therapies and 75 anti-tachycardia pacing (ATP) therapies were delivered without mistaken shock or death. The incidence rate of NVM was 100%, that of PVT was 66.67%, Brugada syndrome 50%, HCM 25% and DCM 16.67%. Of these episodes, the incidence of VF episodes among PVC patients was 87.5% (14 beats), ventricular tachycardia PVC was 82.28% (65 times), 5 beats in NVM patients, 4 beats in HCM and Brugada syndrome patients, and 1 beat in DCM patients. No ICD implantation-related complication was detected, and no ventricular tachycardia induced syncope occurred in these cases. All patients showed improved quality of life after the implantation.
  
  
  CONCLUSIONS
  ICD implantation can prevent malignant ventricular arrhythmia episodes, especially for PVT, NVM and Brugada syndrome in high risk SCD patients, demonstrating the value of implantation of ICD as a primary prevention in high-risk SCD patients.
authors.affiliation: Department of Cardiology, Guangdong Provincial Cardiovascular Institute, Guangzhou 510080, China. E-mail: lie_liu@hotmail.com.
authors.forename: Lie
authors.initials: L
authors.lastname: Liu
authors.forename: Dongli
authors.initials: D
authors.lastname: Chen
authors.forename: Silin
authors.initials: S
authors.lastname: Chen
authors.forename: Chunying
authors.initials: C
authors.lastname: Lin
authors.forename: Yuanhong
authors.initials: Y
authors.lastname: Liang
authors.forename: Hongwen
authors.initials: H
authors.lastname: Fei
mesh_terms: D000328:Adult; D000368:Aged; D016757:Death, Sudden, Cardiac / Q000453:epidemiology / Q000517:prevention & control*; D017147:Defibrillators, Implantable; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011322:Primary Prevention