title: Ischemic Charcot foot: different disease with different treatment?
abstract: OBJECTIVE
  Aim of the study was to describe the presence of peripheral arterial disease in combination with Charcot neuroarthropathy in diabetic patients, and to evaluate the role of revascularization supporting surgical and orthopedic treatment.
  
  
  METHODS
  We retrospectively collected and analyzed data of all diabetic patients affected by Charcot neuroarthropathy in combination with critical limb ischemia, which arrived to our care for the presence of foot lesions and underwent endovascular revascularization, followed by surgical and orthopedic treatment between January 2010 and January 2012. The primary end point was to assess the limb salvage rate. The secondary end point was to evaluate the healing time of the lesions.
  
  
  RESULTS
  Ten diabetic patients (10 men; mean age 69.1±8.5 years), affected by ischemic Charcot neuroarthropathy underwent endovascular revascularization, surgical debridement and orthopedic correction. The limb salvage rate was 90%, avoiding major amputation in 9 patients. In one patient (10%) the infection could not be controlled and below-the-knee amputation was carried out. The required time to heal the lesion was in mean 197.4±22.4 days, after revascularization, surgical and orthopedic treatment.
  
  
  CONCLUSIONS
  Patients with Charcot foot deformity can be affected by critical limb ischemia and revascularization therapy is necessary, to support surgical and orthopedic treatment, avoiding amputation and leading to limb and foot salvage.
authors.affiliation: Interventional Radiology Unit, Policlinico Abano Terme Abano Terme, Padua, Italy. marianopalena@hotmail.com
authors.forename: L M
authors.initials: LM
authors.lastname: Palena
authors.forename: E
authors.initials: E
authors.lastname: Brocco
authors.forename: S
authors.initials: S
authors.lastname: Ninkovic
authors.forename: A
authors.initials: A
authors.lastname: Volpe
authors.forename: M
authors.initials: M
authors.lastname: Manzi
mesh_terms: D000368:Aged; D000671:Amputation, Surgical; D001177:Arthropathy, Neurogenic / Q000175:diagnosis / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D016009:Chi-Square Distribution; D003646:Debridement / Q000009:adverse effects; D017719:Diabetic Foot / Q000150:complications / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D057510:Endovascular Procedures / Q000009:adverse effects; D006801:Humans; D007511:Ischemia / Q000150:complications / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D023821:Limb Salvage; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000009:adverse effects; D058729:Peripheral Arterial Disease / Q000150:complications / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D012086:Reoperation; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014945:Wound Healing