title: [Study on one stage reconstruction of cranial base defects with ADM].
abstract: OBJECTIVE
  The purpose of this study is to explore the effect of reconstruction for the nose cranial base defects after removal of tumor with ADM.
  
  
  METHODS
  Thirteen patients with the nose skull base defects after tumors resection underwent cranial base reconstruction with ADM at the same time. Postoperatively, routine endoscopic and CT scan were performed on all patients at regular intervals.
  
  
  RESULTS
  The successful cranial base reconstruction was achieved in 13 patients with ADM. Intracranial infection occurred in 3 patients and recovered after two weeks postoperatively, given combination of antibiotics, dexamethasone anti-inflammatory, mannitol, reduce intracranial pressure with diuretics and cooling, sedation processing. All patients developed no delayed complications.
  
  
  CONCLUSIONS
  Our experience has demonstrated that the cranial base reconstruction with the ADM "I" shaped sandwich has harvest the satisfactory effect.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hospital of Zheng-zhou University, Zhengzhou, 450052, China.
authors.forename: Weiwei
authors.initials: W
authors.lastname: Wang
authors.forename: Weihua
authors.initials: W
authors.lastname: Lou
authors.forename: Liang
authors.initials: L
authors.lastname: Wang
authors.forename: Wuhao
authors.initials: W
authors.lastname: Lu
authors.forename: Tao
authors.initials: T
authors.lastname: Li
mesh_terms: D062088:Acellular Dermis; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures / Q000379:methods*; D016038:Skin Transplantation / Q000379:methods*; D019291:Skull Base / Q000601:surgery*; D014184:Transplantation, Homologous; D055815:Young Adult