title: Highly sensitive and selective fluoride detection in water through fluorophore release from a metal-organic framework.
abstract: The detection, differentiation and visualization of compounds such as gases, liquids or ions are key challenges for the design of selective optical chemosensors. Optical chemical sensors employ a transduction mechanism that converts a specific analyte recognition event into an optical signal. Here we report a novel concept for fluoride ion sensing where a porous crystalline framework serves as a host for a fluorescent reporter molecule. The detection is based on the decomposition of the host scaffold which induces the release of the fluorescent dye molecule. Specifically, the hybrid composite of the metal-organic framework NH2-MIL-101(Al) and fluorescein acting as reporter shows an exceptional turn-on fluorescence in aqueous fluoride-containing solutions. Using this novel strategy, the optical detection of fluoride is extremely sensitive and highly selective in the presence of many other anions.
authors.affiliation: Department of Chemistry and Center for NanoScience, University of Munich, Butenandtstraße 11E, Munich, Germany.
authors.forename: Florian M
authors.initials: FM
authors.lastname: Hinterholzinger
authors.forename: Bastian
authors.initials: B
authors.lastname: Rühle
authors.forename: Stefan
authors.initials: S
authors.lastname: Wuttke
authors.forename: Konstantin
authors.initials: K
authors.lastname: Karaghiosoff
authors.forename: Thomas
authors.initials: T
authors.lastname: Bein
mesh_terms: D005456:Fluorescent Dyes / Q000032:analysis* / Q000737:chemistry*; D005459:Fluorides / Q000032:analysis*; D008670:Metals / Q000737:chemistry*; D009930:Organic Chemicals / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods*; D014867:Water / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D005456:Fluorescent Dyes; D008670:Metals; D009930:Organic Chemicals; D014874:Water Pollutants, Chemical; D014867:Water; D005459:Fluorides