title: [Physical activity and cancer survival].
abstract: Physical activity has been shown in large cohort studies to positively impact survival in cancer survivors. Existing randomized controlled trials showed a beneficial effect of physical activity on physical fitness, quality of life, anxiety and self-esteem; however, the small sample size, the short follow-up and the lack of standardization of physical activity intervention across studies impaired definite conclusion in terms of survival. Physical activity reduces adiposity and circulating estrogen levels and increases insulin sensitivity among other effects. A workshop was conducted at the International Agency for Research on Cancer in April 2011 to discuss the role of physical activity on cancer survival and the methodology to develop multicentre randomized intervention trials, including the type of physical activity to implement and its association with nutritional recommendations. The authors discuss the beneficial effect of physical activity on cancer survival with a main focus on breast cancer and report the conclusions from this workshop.
authors.affiliation: International Agency for Research on Cancer, 150, cours Albert-Thomas, 69372 Lyon cedex 08, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Romieu
authors.forename: Marina
authors.initials: M
authors.lastname: Touillaud
authors.forename: Pietro
authors.initials: P
authors.lastname: Ferrari
authors.forename: Yves-Jean
authors.initials: YJ
authors.lastname: Bignon
authors.forename: Sami
authors.initials: S
authors.lastname: Antoun
authors.forename: Sophie
authors.initials: S
authors.lastname: Berthouze-Aranda
authors.forename: Patrick
authors.initials: P
authors.lastname: Bachmann
authors.forename: Martine
authors.initials: M
authors.lastname: Duclos
authors.forename: Grégory
authors.initials: G
authors.lastname: Ninot
authors.forename: Gilles
authors.initials: G
authors.lastname: Romieu
authors.forename: Pierre
authors.initials: P
authors.lastname: Sénesse
authors.forename: Jan
authors.initials: J
authors.lastname: Behrendt
authors.forename: Jacques
authors.initials: J
authors.lastname: Balosso
authors.forename: Michel
authors.initials: M
authors.lastname: Pavic
authors.forename: Pierre
authors.initials: P
authors.lastname: Kerbrat
authors.forename: Daniel
authors.initials: D
authors.lastname: Serin
authors.forename: Olivier
authors.initials: O
authors.lastname: Trédan
authors.forename: Béatrice
authors.initials: B
authors.lastname: Fervers
mesh_terms: D001943:Breast Neoplasms / Q000401:mortality / Q000503:physiopathology / Q000523:psychology / Q000534:rehabilitation; D002423:Cause of Death; D015331:Cohort Studies; D015897:Comorbidity; D016207:Cytokines / Q000378:metabolism; D015444:Exercise; D005081:Exercise Therapy; D005221:Fatigue / Q000209:etiology / Q000517:prevention & control; D005260:Female; D005500:Follow-Up Studies; D012739:Gonadal Steroid Hormones / Q000378:metabolism; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism; D015201:Meta-Analysis as Topic; D008954:Models, Biological; D009043:Motor Activity; D015337:Multicenter Studies as Topic / Q000706:statistics & numerical data; D009369:Neoplasms / Q000401:mortality / Q000523:psychology / Q000534:rehabilitation*; D009765:Obesity / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D011446:Prospective Studies; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data; D017741:Survivors / Q000523:psychology
chemical_list: D016207:Cytokines; D012739:Gonadal Steroid Hormones; D036341:Intercellular Signaling Peptides and Proteins
keywords: cancer; nutrition; physical activity; prevention