title: [Current therapeutic options for Peyronie's disease].
abstract: Peyronie's disease is a heterogeneous disorder with typical symptoms of plaque formation, penile pain, deviation, penile shortening and erectile dysfunction. The etiology is unknown. Repetitive microtraumatic lesions with the formation of inelastic scar tissue at the level of the tunica albuginea are discussed as a trigger mechanism for a questionable genetic disposition. A non-surgical therapy based on a clear pathophysiology does not exist although several conservative treatment regimes are practiced. In the stable stage of the disease surgical therapy of penile angulation is the most frequent operation. Depending on the deviation angle, penile length and erectile dysfunction, different types of straightening surgery can be offered. This article provides an overview of conservative management and commonly used surgical techniques.
authors.affiliation: Klinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Gießen und Marburg GmbH, Standort Gießen, Justus Liebig-Universität Gießen, Rudolf-Buchheim-Straße 7, 35390, Gießen, Deutschland, Arne.Hauptmann@chiru.med.uni-giessen.de.
authors.forename: A
authors.initials: A
authors.lastname: Hauptmann
authors.forename: T
authors.initials: T
authors.lastname: Diemer
authors.forename: W
authors.initials: W
authors.lastname: Weidner
mesh_terms: D010129:4-Aminobenzoic Acid / Q000008:administration & dosage*; D000284:Administration, Oral; D003131:Combined Modality Therapy; D007172:Erectile Dysfunction / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008096:Lithotripsy / Q000379:methods; D008297:Male; D010411:Penile Induration / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D011878:Radiotherapy / Q000379:methods*; D019651:Plastic Surgery Procedures / Q000379:methods*; D013519:Urogenital Surgical Procedures / Q000379:methods*
chemical_list: D010129:4-Aminobenzoic Acid