title: First report of a phylogenetic analysis of an autochthonous Plasmodium vivax strain isolated from a malaria case in East Attica, Greece.
abstract: Malaria has become an emerging infection in Greece, which is the doorstep to Europe for thousands of immigrants. With increasing immigration, cases with evidence of domestic transmission (autochthonous) are being reported. In the present study, an isolate of Plasmodium vivax from an autochthonous clinical case was subjected to phylogenetic analysis of the genes encoding the merozoite surface protein 1 (MSP-1) and the circumsporozoite protein (CSP). In the MSP region, the strain was related with strains from Brazil, South Korea, Turkey and Thailand, whereas in the CSP region, with strains from Brazil, Colombia and New Guinea. The present study establishes for the first time in Greece the basis for the creation of a database comprising genotypic and phylogenetic characteristics of Plasmodium spp.
authors.affiliation: Department of Biopathology and Clinical Microbiology, Athens Medical School, Aeginition Hospital, Vass, Sophias av, 72-74, Athens 115 28, Greece. schatzipa@gmail.com.
authors.forename: Anastasios
authors.initials: A
authors.lastname: Ioannidis
authors.forename: Chryssoula
authors.initials: C
authors.lastname: Nicolaou
authors.forename: Athina
authors.initials: A
authors.lastname: Stoupi
authors.forename: Athanasios
authors.initials: A
authors.lastname: Kossyvakis
authors.forename: Petros
authors.initials: P
authors.lastname: Matsoukas
authors.forename: Melina-Vassiliki
authors.initials: MV
authors.lastname: Liakata
authors.forename: Emmanouil
authors.initials: E
authors.lastname: Magiorkinis
authors.forename: Efthimia
authors.initials: E
authors.lastname: Petinaki
authors.forename: Stylianos
authors.initials: S
authors.lastname: Chatzipanagiotou
mesh_terms: D000328:Adult; D016000:Cluster Analysis; D016054:DNA, Protozoan / Q000737:chemistry / Q000235:genetics; D005260:Female; D006115:Greece; D006801:Humans; D016780:Malaria, Vivax / Q000175:diagnosis* / Q000469:parasitology*; D020066:Merozoite Surface Protein 1 / Q000235:genetics*; D008969:Molecular Sequence Data; D010802:Phylogeny; D010966:Plasmodium vivax / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D015800:Protozoan Proteins / Q000235:genetics*; D017422:Sequence Analysis, DNA
chemical_list: D016054:DNA, Protozoan; D020066:Merozoite Surface Protein 1; D015800:Protozoan Proteins; C041595:circumsporozoite protein, Protozoan