title: Single incision mid-urethral slings: impact of obesity on outcomes.
abstract: OBJECTIVE
  To assess the potential impact of obesity on the success rate of single incision slings (SIS).
  
  
  METHODS
  This was a retrospective cohort study of women who underwent the SIS procedure for primary stress urinary incontinence. Women were divided into three different groups by body mass index (BMI) according to the WHO classification. The International Consultation on Incontinence-short form (ICIQ-SF), Women Irritative Prostate Symptoms Score (W-IPSS), Patient Global Impression of Severity (PGI-S) and Patient Global Impression of Improvement (PGI-I) questionnaires were used. Objective and subjective outcomes were the primary outcome measures of the study. SPSS software was used for data analysis.
  
  
  RESULTS
  206 patients who underwent the SIS procedure were reviewed. At 1 year follow-up there were 196 women available for the analysis: 69 were normal weight subjects, 91 overweight and 36 obese. Patients in all BMI groups reported a significant improvement in their condition. Nevertheless there was a trend towards lesser objective efficacy of SIS with increasing body weight, with a significant difference between obese women and normal subjects: 75% vs 91.3%, p=0.049; OR 3.74 (95% CI 1.19-11.76). Analysis of the ICIQ-SF and PGI-I showed significant lower mean ± SD improvement in obese women when compared with their normal or overweight counterparts, together with a significantly lower number of obese patients reporting themselves as very much improved or much improved.
  
  
  CONCLUSIONS
  Single incision slings seem to be an effective treatment regardless of BMI, but obese women had nearly 4 times the odds of objective failure as compared to normal weight women.
authors.affiliation: Department of Obstetrics and Gynecology, Azienda Ospedaliera di Legnano, Ospedale "G. Fornaroli", Magenta, Italy. Electronic address: m.meschia@libero.it.
authors.forename: Michele
authors.initials: M
authors.lastname: Meschia
authors.forename: Gabriela
authors.initials: G
authors.lastname: Rossi
authors.forename: Silvia
authors.initials: S
authors.lastname: Bertini
authors.forename: Arianna
authors.initials: A
authors.lastname: Sommacal
authors.forename: Sara
authors.initials: S
authors.lastname: Foina
authors.forename: Francesca
authors.initials: F
authors.lastname: Sandretti
authors.forename: Pietro
authors.initials: P
authors.lastname: Barbacini
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D064887:Observational Studies as Topic; D012189:Retrospective Studies; D053825:Suburethral Slings; D016896:Treatment Outcome; D014550:Urinary Incontinence, Stress / Q000150:complications / Q000601:surgery*
keywords: Body mass index; Complications; Quality of life; Single incision sling; Success rate