title: Correlation between vectorcardiographic measures and cardiac magnetic resonance imaging of the left ventricle in an implantable cardioverter defibrillator population.
abstract: BACKGROUND
  Measures of vectorcardiographic changes and LV remodelling have been associated with arrhythmic risk. However the correlation between the two modalities is not well characterised.
  
  
  METHODS
  We correlated spatial QRS-T angle and ventricular gradient with cardiac MRI derived LV global measures and scar pattern in 66 ICD recipients.
  
  
  RESULTS
  Spatial QRS-T angle was significantly larger in patients with ischaemic scar than those without scar (150°±22° vs. 119°±46°, p=0.01). Larger spatial QRS-T angle was also correlated with more depressed LV function, more dilated LV and larger LV mass. Ventricular gradient azimuth was significantly different between patients with no scar, non-ischaemic scar and ischaemic scar (20°±49° vs. 38°±62° vs. 65°±48°, p=0.009), but independent of spatial QRS-T angle and LV structure.
  
  
  CONCLUSIONS
  Spatial QRS-T angle and ventricular gradient are partially related to LV structural properties. Further investigation is warranted to examine their comparative and combined prognostic value in risk stratification of ventricular arrhythmias.
authors.affiliation: Wellington Cardiovascular Research Group, Wellington, New Zealand; Department of Surgery and Anaesthesia, University of Otago, Wellington, New Zealand. Electronic address: bijia.shi@otago.ac.nz.
authors.forename: Bijia
authors.initials: B
authors.lastname: Shi
authors.affiliation: Wellington Cardiovascular Research Group, Wellington, New Zealand; Cardiology Department, Hutt Hospital, Wellington, New Zealand.
authors.forename: Katherine A
authors.initials: KA
authors.lastname: Ferrier
authors.affiliation: Wellington Cardiovascular Research Group, Wellington, New Zealand; Cardiology Department, Wellington Regional Hospital, Wellington, New Zealand.
authors.forename: Alexander
authors.initials: A
authors.lastname: Sasse
authors.affiliation: Wellington Cardiovascular Research Group, Wellington, New Zealand; Cardiology Department, Wellington Regional Hospital, Wellington, New Zealand.
authors.forename: Scott A
authors.initials: SA
authors.lastname: Harding
authors.affiliation: Wellington Cardiovascular Research Group, Wellington, New Zealand; Department of Surgery and Anaesthesia, University of Otago, Wellington, New Zealand.
authors.forename: Peter D
authors.initials: PD
authors.lastname: Larsen
mesh_terms: D017147:Defibrillators, Implantable; D005260:Female; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D016896:Treatment Outcome; D014672:Vectorcardiography / Q000379:methods*; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000517:prevention & control*
keywords: Arrhythmic risk; Cardiac magnetic resonance imaging; Implantable cardioverter defibrillator; LV remodelling; Vectorcardiography