title: PhI(OAc)2-mediated synthesis of 6-(trifluoromethyl)phenanthridines by oxidative cyclization of 2-isocyanobiphenyls with CF3SiMe3 under metal-free conditions.
abstract: A mild and efficient method for the synthesis of 6-(trifluoromethyl)phenanthridines through oxidative cyclization of 2-isocyanobiphenyls with CF3SiMe3 under metal-free conditions was developed. The reaction allows the direct formation of C-CF3 bonds and rapid access to phenanthridine ring systems in one catalytic cycle.
authors.affiliation: School of Chemistry and Chemical Engineering, Sun Yat-Sen University , 135 Xingang West Road, Guangzhou 510275, China.
authors.forename: Qile
authors.initials: Q
authors.lastname: Wang
authors.forename: Xichang
authors.initials: X
authors.lastname: Dong
authors.forename: Tiebo
authors.initials: T
authors.lastname: Xiao
authors.forename: Lei
authors.initials: L
authors.lastname: Zhou
mesh_terms: D001713:Biphenyl Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D010084:Oxidation-Reduction; D010617:Phenanthridines / Q000138:chemical synthesis* / Q000737:chemistry; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
chemical_list: C523557:(trifluoromethyl)-trimethylsilane; D001713:Biphenyl Compounds; D006845:Hydrocarbons, Fluorinated; D009570:Nitriles; D010617:Phenanthridines; D014297:Trimethylsilyl Compounds