title: miRNAs: biogenesis, origin and evolution, functions on virus-host interaction.
abstract: MicroRNAs (miRNAs) are small endogenous non-coding functional RNAs. They can play vital roles in post-transcriptional regulating mRNAs transcripts in nearly all biological processes. More and more reports on miRNAs come from different species (animal, plant, bacteria, virus) in the researches in development, immunity, apoptosis, tumor, virus-host interaction. These recent findings provide new insights into the roles of miRNAs as well as their function. This review outlines the ever-deepening understanding of miRNAs (biogenesis, origin, evolution), and discusses functions from host and viral miRNAs in the context of virus-host interaction.
authors.affiliation: Department of Burn and Plastic Surgery, the 118th Hospital of PLA (The People's Liberation Army, China), Wenzhou, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhuo
authors.forename: Guohui
authors.initials: G
authors.lastname: Gao
authors.forename: Jian An
authors.initials: JA
authors.lastname: Shi
authors.forename: Xuexue
authors.initials: X
authors.lastname: Zhou
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Wang
mesh_terms: D000818:Animals; D017209:Apoptosis; D005075:Biological Evolution; D007107:Immune System / Q000378:metabolism / Q000821:virology; D007438:Introns; D035683:MicroRNAs / Q000378:metabolism*; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D012322:RNA Precursors / Q000378:metabolism; D014780:Viruses / Q000235:genetics / Q000378:metabolism*
chemical_list: D035683:MicroRNAs; D012322:RNA Precursors