title: [Metabolic therapy in neurology].
abstract: We studied the efficacy of rheosorbilact, an original infusion drug based on polyalcohols, in the complex therapy of patients with brain ischemia and diabetic neuropathy. Reosorbilact was used intravenously indrops 200-400 ml in day - 20 days. The primary endpoint of the study was the improvement of quality of life assessed with the SF-36 scale after 1 month of treatment. Patients with brain ischemia underwent neuropsychological tests and ultrasound duplex scanning of the carotid and vertebral arteries. In the group of patients with diabetic neuropathy, we evaluated the intensity of pain syndrome with the NRS, blood glucose level and electroneuromyography parameters of low extremities nerves. Some characteristics of acid-base balance were studied in patients of both groups. The results obtained in the study indicate the significant clinical effect of reosorbilact in patients with brain ischemia and diabetic neuropathy.
authors.forename: S A
authors.initials: SA
authors.lastname: Zhivolupov
authors.forename: I N
authors.initials: IN
authors.lastname: Samartsev
authors.forename: N A
authors.initials: NA
authors.lastname: Rashidov
authors.forename: T V
authors.initials: TV
authors.lastname: Bodrova
authors.forename: M N
authors.initials: MN
authors.lastname: Vorob'eva
mesh_terms: D000136:Acid-Base Equilibrium; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000627:therapeutic use; D003929:Diabetic Neuropathies / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009462:Neurology / Q000379:methods*; D008063:Thioctic Acid / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000975:Antioxidants; D008063:Thioctic Acid