title: Mrap2: an accessory protein linked to obesity.
abstract: Melanocortin receptors are critical modulators of energy balance and glucose homeostasis. Companion studies published in Science (Asai et al., 2013; Sebag et al., 2013) establish a role for melanocortin receptor accessory protein 2 (Mrap2) in regulating melanocortin receptor activity and in the development of obesity in zebrafish, rodents, and humans.
authors.affiliation: Division of Hypothalamic Research, Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75235, USA.
authors.forename: Tiemin
authors.initials: T
authors.lastname: Liu
authors.forename: Joel K
authors.initials: JK
authors.lastname: Elmquist
authors.forename: Kevin W
authors.initials: KW
authors.lastname: Williams
mesh_terms: D000818:Animals; D001835:Body Weight / Q000235:genetics*; D002352:Carrier Proteins / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000235:genetics*; D058261:Receptor Activity-Modifying Proteins / Q000378:metabolism*; D044105:Receptor, Melanocortin, Type 4 / Q000378:metabolism*; D015027:Zebrafish / Q000196:embryology*; D029961:Zebrafish Proteins / Q000378:metabolism*
chemical_list: D002352:Carrier Proteins; D058261:Receptor Activity-Modifying Proteins; D044105:Receptor, Melanocortin, Type 4; D029961:Zebrafish Proteins