title: In-vivo alignment comparing patient specific instrumentation with both conventional and computer assisted surgery (CAS) instrumentation in total knee arthroplasty.
abstract: Patient specific instrumentation (PSI) was developed to increase total knee arthroplasty (TKA) accuracy and efficiency. The study purpose was to compare immediate post-operative mechanical alignment, achieved using PSI, with conventional and computer assisted surgery (CAS) instruments in high volume TKA practices. This prospective, multicenter, non-randomized study accrued 66 TKA patients using PSI. A computed tomography (CT) based algorithm was used to develop the surgical plan. Sixty-two percent were females, 99% were diagnosed with osteoarthritis, average age at surgery was 66 years, and 33 was the average body mass index. A historical control group was utilized that underwent TKA using conventional instruments (n=86) or CAS (n=81), by the same set of surgeons. Postoperative mechanical alignment was comparable across the groups. Operative time mean and variance were significant.
authors.affiliation: Valley Orthopaedics, Seattle, Washington.
authors.forename: William
authors.initials: W
authors.lastname: Barrett
authors.affiliation: Summit Orthopaedics, Woodbury, Minnesota.
authors.forename: Daniel
authors.initials: D
authors.lastname: Hoeffel
authors.affiliation: Towson Orthopaedics, Towson Orthopaedics Associates, Baltimore, Maryland.
authors.forename: David
authors.initials: D
authors.lastname: Dalury
authors.affiliation: OrthoCarolina, Charlotte, North Carolina.
authors.forename: J Bohannon
authors.initials: JB
authors.lastname: Mason
authors.affiliation: DePuy Synthes, Warsaw, Indiana.
authors.forename: Jeff
authors.initials: J
authors.lastname: Murphy
authors.affiliation: DePuy Synthes, Warsaw, Indiana.
authors.forename: Sam
authors.initials: S
authors.lastname: Himden
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation*; D017760:Bone Malalignment / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery; D011446:Prospective Studies; D025321:Surgery, Computer-Assisted; D013997:Time Factors
keywords: customized cutting blocks; customized patient instrumentation patient specific; instrumentation; mechanical alignment; surgical time; total knee arthroplasty