title: Nonlegumes respond to rhizobial Nod factors by suppressing the innate immune response.
abstract: Virtually since the discovery of nitrogen-fixing Rhizobium-legume symbioses, researchers have dreamed of transferring this capability into nonlegume crop species (for example, corn). In general, nonlegumes were assumed to lack the ability to respond to the rhizobial lipo-chitin Nod factors, which are the essential signal molecules that trigger legume nodulation. However, our data indicate that Arabidopsis thaliana plants, as well as other nonlegumes, recognize the rhizobial Nod factor via a mechanism that results in strong suppression of microbe-associated molecular pattern (MAMP)-triggered immunity. The mechanism of action leads to reduced levels of pattern-recognition receptors on the plasma membrane involved in MAMP recognition.
authors.affiliation: Division of Plant Science, National Center for Soybean Biotechnology, Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
authors.forename: Yan
authors.initials: Y
authors.lastname: Liang
authors.forename: Yangrong
authors.initials: Y
authors.lastname: Cao
authors.forename: Kiwamu
authors.initials: K
authors.lastname: Tanaka
authors.forename: Sandra
authors.initials: S
authors.lastname: Thibivilliers
authors.forename: Jinrong
authors.initials: J
authors.lastname: Wan
authors.forename: Jeongmin
authors.initials: J
authors.lastname: Choi
authors.forename: Chang ho
authors.initials: Ch
authors.lastname: Kang
authors.forename: Jing
authors.initials: J
authors.lastname: Qiu
authors.forename: Gary
authors.initials: G
authors.lastname: Stacey
mesh_terms: D017360:Arabidopsis / Q000187:drug effects / Q000276:immunology* / Q000382:microbiology*; D029681:Arabidopsis Proteins / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D005408:Flagellin / Q000276:immunology; D007113:Immunity, Innate / Q000187:drug effects / Q000276:immunology*; D008070:Lipopolysaccharides / Q000276:immunology* / Q000494:pharmacology; D009586:Nitrogen Fixation / Q000235:genetics; D009844:Oligosaccharides / Q000276:immunology / Q000494:pharmacology; D011494:Protein Kinases / Q000378:metabolism; D059748:Proteolysis; D051192:Receptors, Pattern Recognition / Q000378:metabolism; D013025:Glycine max / Q000276:immunology / Q000382:microbiology; D013559:Symbiosis
chemical_list: D029681:Arabidopsis Proteins; D008070:Lipopolysaccharides; D009844:Oligosaccharides; D051192:Receptors, Pattern Recognition; D005408:Flagellin; C091899:Nod factor V, Bradyrhizobium japonicum; C012238:chitotetrose; D011494:Protein Kinases; C411853:FLS2 protein, Arabidopsis