title: Assessment of left ventricular functions in patients with Sjögren's syndrome using tissue Doppler echocardiography.
abstract: OBJECTIVE
  In our study, we aimed to evaluate left ventricular function in patients with Sjögren syndrome (SS) using tissue Doppler echocardiography (TDE) and myocardial performance index (MPI) in addition to conventional echocardiographic methods.
  
  
  METHODS
  We evaluated 50 patients with SS and 48 healthy volunteers with similar demographic characteristics. Systolic and diastolic functions of the left ventricle were analyzed with standard two-dimensional (2D) echocardiography, M-mode echocardiography, pulsed-wave (PW) Doppler and tissue Doppler imaging.
  
  
  RESULTS
  Septal part of the mitral annulus PW TDE showed that systolic myocardial wave (Sm), early diastolic myocardial wave (Em), late diastolic myocardial wave (Am) and Em/Am ratios are significantly lower, and myocardial isovolumetric relaxation time (IVRTm) and MPI values are significantly higher in patients with SS. Lateral site of the mitral annulus PW TDE showed that Em, Sm and Em/Am ratios are significantly lower, and IVRTm and MPI values are significantly higher in patients with SS compared with healthy controls.
  
  
  CONCLUSIONS
  In this study, it was shown that both left ventricle systolic and diastolic functions of patients with SS were disturbed.
authors.affiliation: Departments of Cardiology, Ataturk Education and Research Hospital, Yıldırım Beyazıt University, Ankara, Turkey.
authors.forename: Nihal A
authors.initials: NA
authors.lastname: Bayram
authors.forename: Omer F
authors.initials: OF
authors.lastname: Cicek
authors.forename: Sukran
authors.initials: S
authors.lastname: Erten
authors.forename: Telat
authors.initials: T
authors.lastname: Keles
authors.forename: Tahir
authors.initials: T
authors.lastname: Durmaz
authors.forename: Emine
authors.initials: E
authors.lastname: Bilen
authors.forename: Cenk
authors.initials: C
authors.lastname: Sarı
authors.forename: Engin
authors.initials: E
authors.lastname: Bozkurt
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003971:Diastole / Q000502:physiology; D015150:Echocardiography, Doppler / Q000379:methods; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D063177:Pulse Wave Analysis; D012720:Severity of Illness Index; D012859:Sjogren's Syndrome / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D013599:Systole / Q000502:physiology; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology*
keywords: Sjögren's syndrome; left ventricular diastolic function; left ventricular systolic function; tissue doppler echocardiography