title: [Gene disorders and molecular genetic subtypes of malignant gliomas].
abstract: Malignant brain tumors are noteworthy for a lot of genetic disorders that show itself as decreased or increased gene function of different genes and lead to tumor development. The differences in the molecular genetic profile can identify several subtypes of malignant gliomas, which are distinguished by both their clinical course and susceptibility to drugs. This can be the basis for developing individualized therapy options in patients with malignant gliomas.
authors.forename: K E
authors.initials: KE
authors.lastname: Borisov
authors.forename: D D
authors.initials: DD
authors.lastname: Sakaeva
mesh_terms: D001932:Brain Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D002869:Chromosome Aberrations; D052138:Genes, Neoplasm; D005910:Glioma / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D006801:Humans; D009363:Neoplasm Proteins / Q000235:genetics / Q000378:metabolism
chemical_list: D009363:Neoplasm Proteins