title: Antibacterial gold nanoparticles-biomass assisted synthesis and characterization.
abstract: Xylose is a natural monosaccharide found in biomass such as straw, pecan shells, cottonseed hulls, and corncobs. Using this monosaccharide, we report the facile, green synthesis and characterization of stable xylose encapsulated gold nanoparticles (Xyl-GNPs) with potent antibacterial activity. Xyl-GNPs were synthesized using the reduction property of xylose in an aqueous solution containing choloraurate anions carried out at room temperature and atmospheric pressure. These nanoparticles were stable and near spherical in shape with an average diameter of 15 +/- 5 nm. Microbiological assay results showed the concentration dependent antibacterial activity of these particles against both Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus epidermidis) bacteria. Thus the facile, environmentally friendly Xyl-GNPs have many potential applications in chemical and biomedical industries, particularly in the development of antibacterial agents in the field of biomedicine.
authors.affiliation: Department of Chemistry, Western Kentucky University, Bowling Green, KY 42101, USA.
authors.forename: Vivek D
authors.initials: VD
authors.lastname: Badwaik
authors.forename: Chad B
authors.initials: CB
authors.lastname: Willis
authors.forename: Dillon S
authors.initials: DS
authors.lastname: Pender
authors.forename: Rammohan
authors.initials: R
authors.lastname: Paripelly
authors.forename: Monic
authors.initials: M
authors.lastname: Shah
authors.forename: Yogesh A
authors.initials: YA
authors.lastname: Kherde
authors.forename: Lakshmisri M
authors.initials: LM
authors.lastname: Vangala
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Gonzalez
authors.forename: Rajalingam
authors.initials: R
authors.lastname: Dakshinamurthy
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000138:chemical synthesis; D002470:Cell Survival / Q000187:drug effects; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects*; D006046:Gold / Q000737:chemistry* / Q000494:pharmacology*; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D013212:Staphylococcus epidermidis / Q000166:cytology / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D006046:Gold