title: [Chemotherapeutical department: surgical infection prevention and treatment in ICU].
abstract: The article discusses the issues of chemotherapeutical department organization and functioning in multidisciplinary surgical hospital. In connection with a worldwide spread of antibiotic-resistant agents of surgical infections, it becomes necessary to unite efforts of surgeons, resuscitation specialists, clinical pharmacologists - chemiotherapeutists and microbiologists. The main approaches in solving of surgical infection problems are: in-hospital epidemiological situation monitoring, the study ofmicroflora resistance to antibiotics used in the surgical and resuscitation practice, the study of antibacterial therapy clinical-pharmacological aspects (pharmacokinetics, pharmacodynamics, tolerance and efficacy of antimicrobial drugs). The development of pre-emptive antibiotics rotation principles curbs the spread ofnosocomial infections pathogens resistant strains. The 40-year experience of surgical infections prevention and treatment laboratory functioning professes this.
authors.forename: N S
authors.initials: NS
authors.lastname: Bogomolova
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000379:methods*; D003428:Cross Infection / Q000382:microbiology / Q000517:prevention & control*; D024881:Drug Resistance, Bacterial; D006801:Humans; D007362:Intensive Care Units / Q000458:organization & administration / Q000592:standards; D008826:Microbial Sensitivity Tests; D010607:Pharmacy Service, Hospital / Q000379:methods* / Q000458:organization & administration / Q000592:standards; D013530:Surgical Wound Infection / Q000382:microbiology / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents