title: Calcium oxalate crystal deposition in a patient with Aspergilloma due to Aspergillus niger.
abstract: Discrimination between aspergilloma and chronic necrotizing pulmonary aspergillosis (CNPA) based on radiological findings can difficult. We describe a patient with aspergilloma and organizing pneumonia that was possibly caused by Aspergillus niger infection and radiologically mimicked CNPA. A postmortem histological analysis showed diffuse alveolar damage that had originated in peri-cavitary lung parenchyma. Calcium oxalate or Aspergillus niger was located inside, but not outside the cavity in the right upper lobe. Calcium oxalate or other unknown hyphal bioactive components might provoke severe lung inflammation not only adjacent to the cavity, but also on the contralateral side.
authors.affiliation: Department of Respiratory Medicine, Kyorin University School of Medicine, Tokyo, Japan;
authors.forename: Miku
authors.initials: M
authors.lastname: Oda
authors.forename: Takeshi
authors.initials: T
authors.lastname: Saraya
authors.forename: Megumi
authors.initials: M
authors.lastname: Wakayama
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Shibuya
authors.forename: Yukari
authors.initials: Y
authors.lastname: Ogawa
authors.forename: Toshiya
authors.initials: T
authors.lastname: Inui
authors.forename: Emi
authors.initials: E
authors.lastname: Yokoyama
authors.forename: Manami
authors.initials: M
authors.lastname: Inoue
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Shimoyamada
authors.forename: Masachika
authors.initials: M
authors.lastname: Fujiwara
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Ota
authors.forename: Hajime
authors.initials: H
authors.lastname: Takizawa
authors.forename: Hajime
authors.initials: H
authors.lastname: Goto
keywords: Aspergillus niger; Calcium oxalate crystal deposition; aspergilloma; black deposits