title: [Clinical evaluation of influence of aspirin on post-operative bleeding after tooth extraction in the elderly].
abstract: OBJECTIVE
  To investigate the feasibility of continuation of aspirin before tooth extraction in the elderly.
  
  
  METHODS
  The patients enrolled in this study were the elderly requiring a single non-impacted tooth extraction. 300 elderly outpatients used lidocaine local infiltration anesthesia, 200 patients without using aspirin before tooth extraction served as control group I, 100 patients with prolong use of aspirin before tooth extraction as observation group I. 300 elderly outpatients used compound articaine local infiltration anesthesia, 200 patients without using aspirin before tooth extraction served as control group II, 100 patients with prolong use of aspirin before tooth extraction as observation group II.Bleedings at 5, 10, 30 min, 24 h after tooth extraction were observed and the relationship between postoperative bleeding and intake of aspirin was analyzed.
  
  
  RESULTS
  There was no significant difference at 5, 10, 30 min, 24 h in postoperative bleeding after extraction between control group I and observation group. The incidence of bleeding of observation group II after tooth extraction at 5 min was higher than that of control group II and there was no significant difference at 10, 30 min, 24 h between the two groups.
  
  
  CONCLUSIONS
  Continuation of aspirin have no influence on postoperative bleeding. Therefore we suggest that there was no indication to discontinue aspirin for the elderly before a single non-impacted tooth extraction.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
authors.forename: Wen-ying
authors.initials: WY
authors.lastname: Wang
authors.forename: Nian-hui
authors.initials: NH
authors.lastname: Cui
authors.forename: En-bo
authors.initials: EB
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000772:Anesthesia, Local; D001241:Aspirin / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008012:Lidocaine; D008297:Male; D008875:Middle Aged; D006472:Oral Hemorrhage / Q000209:etiology*; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*; D019106:Postoperative Hemorrhage / Q000209:etiology*; D014081:Tooth Extraction / Q000009:adverse effects*
chemical_list: D010975:Platelet Aggregation Inhibitors; D008012:Lidocaine; D001241:Aspirin