title: A highly efficient regioselective addition of acetylides to enediones based on steric effects.
abstract: A simple and efficient strategy for the synthesis of 1-ethynylcyclohex-2-enol derivatives was developed utilizing regioselective addition of acetylides to enediones based on steric effects. Further investigation of the substrate scope of enediones indicated that all the addition reactions ocurred in good yield.
authors.affiliation: Department of Applied Chemistry, China Agricultural University, 2 West Yuanmingyuan West Road, Beijing 100193, China.
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Han
authors.forename: Chuan
authors.initials: C
authors.lastname: Wan
authors.forename: Dongyan
authors.initials: D
authors.lastname: Yang
authors.forename: Xiaoyong
authors.initials: X
authors.lastname: Yuan
authors.forename: Shijie
authors.initials: S
authors.lastname: Du
authors.forename: Yumei
authors.initials: Y
authors.lastname: Xiao
authors.forename: Zhaohai
authors.initials: Z
authors.lastname: Qin
mesh_terms: D002384:Catalysis; D007659:Ketones / Q000138:chemical synthesis*; D008094:Lithium / Q000737:chemistry*; D009281:Naphthalenes / Q000138:chemical synthesis; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007659:Ketones; D009281:Naphthalenes; D009942:Organometallic Compounds; C434823:n-butyllithium; D008094:Lithium