title: Open source drug discovery - a limited tutorial.
abstract: Open science is a new concept for the practice of experimental laboratory-based research, such as drug discovery. The authors have recently gained experience in how to run such projects and here describe some straightforward steps others may wish to take towards more openness in their own research programmes. Existing and inexpensive online tools can solve many challenges, while some psychological barriers to the free sharing of all data and ideas are more substantial.
authors.affiliation: School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
authors.forename: Murray N
authors.initials: MN
authors.lastname: Robertson
authors.affiliation: School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
authors.forename: Paul M
authors.initials: PM
authors.lastname: Ylioja
authors.affiliation: School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
authors.forename: Alice E
authors.initials: AE
authors.lastname: Williamson
authors.affiliation: School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Woelfle
authors.affiliation: School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Robins
authors.affiliation: School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
authors.forename: Katrina A
authors.initials: KA
authors.lastname: Badiola
authors.affiliation: Medicines for Malaria Venture, PO Box 1826, 20 rte de Pré-Bois, 1215 Geneva 15, Switzerland.
authors.forename: Paul
authors.initials: P
authors.lastname: Willis
authors.affiliation: UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland.
authors.forename: Piero
authors.initials: P
authors.lastname: Olliaro
authors.affiliation: Medicines for Malaria Venture, PO Box 1826, 20 rte de Pré-Bois, 1215 Geneva 15, Switzerland.
authors.forename: Timothy N C
authors.initials: TN
authors.lastname: Wells
authors.affiliation: School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
authors.forename: Matthew H
authors.initials: MH
authors.lastname: Todd
mesh_terms: D000871:Anthelmintics / Q000138:chemical synthesis / Q000494:pharmacology; D000962:Antimalarials / Q000138:chemical synthesis / Q000494:pharmacology; D030881:Disclosure / Q000941:ethics*; D055808:Drug Discovery; D006801:Humans; D033181:Information Dissemination / Q000941:ethics / Q000379:methods*; D020407:Internet; D008288:Malaria / Q000188:drug therapy / Q000469:parasitology; D012552:Schistosomiasis / Q000188:drug therapy / Q000469:parasitology; D012984:Software
chemical_list: D000871:Anthelmintics; D000962:Antimalarials