title: Synthesis and evaluation of pyrrole polyamide-2'-deoxyguanosine 5'-phosphate hybrid.
abstract: Pyrrole polyamide-2'-deoxyguanosine 5'-phosphate hybrid (Hybrid 4) was synthesized and evaluated in terms of the inhibition of mouse mammary carcinoma FM3A cell growth. Hybrid 4 was found to exhibit dose-dependent inhibition of cell growth.
authors.affiliation: School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
authors.forename: Etsuko
authors.initials: E
authors.lastname: Kawashima
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Nakanishi
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Terui
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Tomitori
authors.forename: Keiko
authors.initials: K
authors.lastname: Kashiwagi
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Ohba
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kamaike
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D003848:Deoxyguanine Nucleotides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D015674:Mammary Neoplasms, Animal; D051379:Mice; D015394:Molecular Structure; D009369:Neoplasms / Q000188:drug therapy; D009757:Nylons / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D011758:Pyrroles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
chemical_list: D003848:Deoxyguanine Nucleotides; D009757:Nylons; D011758:Pyrroles; C007257:2'-deoxyguanosine 5'-phosphate