title: The Arabidopsis thaliana RNA editing factor SLO2, which affects the mitochondrial electron transport chain, participates in multiple stress and hormone responses.
abstract: Recently, we reported that the novel mitochondrial RNA editing factor SLO2 is essential for mitochondrial electron transport, and vital for plant growth through regulation of carbon and energy metabolism. Here, we show that mutation in SLO2 causes hypersensitivity to ABA and insensitivity to ethylene, suggesting a link with stress responses. Indeed, slo2 mutants are hypersensitive to salt and osmotic stress during the germination stage, while adult plants show increased drought and salt tolerance. Moreover, slo2 mutants are more susceptible to Botrytis cinerea infection. An increased expression of nuclear-encoded stress-responsive genes, as well as mitochondrial-encoded NAD genes of complex I and genes of the alternative respiratory pathway, was observed in slo2 mutants, further enhanced by ABA treatment. In addition, H2O2 accumulation and altered amino acid levels were recorded in slo2 mutants. We conclude that SLO2 is required for plant sensitivity to ABA, ethylene, biotic, and abiotic stress. Although two stress-related RNA editing factors were reported very recently, this study demonstrates a unique role of SLO2, and further supports a link between mitochondrial RNA editing events and stress response.
authors.affiliation: Laboratory of Functional Plant Biology, Department of Physiology, Ghent University, K.L. Ledeganckstraat 35, B-9000 Ghent, Belgium.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zhu
authors.forename: Jasper
authors.initials: J
authors.lastname: Dugardeyn
authors.forename: Chunyi
authors.initials: C
authors.lastname: Zhang
authors.forename: Per
authors.initials: P
authors.lastname: Mühlenbock
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Eastmond
authors.forename: Roland
authors.initials: R
authors.lastname: Valcke
authors.forename: Barbara
authors.initials: B
authors.lastname: De Coninck
authors.forename: Sevgi
authors.initials: S
authors.lastname: Oden
authors.forename: Michael
authors.initials: M
authors.lastname: Karampelias
authors.forename: Bruno P A
authors.initials: BP
authors.lastname: Cammue
authors.forename: Els
authors.initials: E
authors.lastname: Prinsen
authors.forename: Dominique
authors.initials: D
authors.lastname: Van Der Straeten
mesh_terms: D000040:Abscisic Acid / Q000378:metabolism*; D017360:Arabidopsis / Q000235:genetics / Q000254:growth & development / Q000378:metabolism* / Q000382:microbiology; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D020171:Botrytis / Q000502:physiology; D004579:Electron Transport; D005030:Ethylenes / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant; D008928:Mitochondria / Q000235:genetics / Q000378:metabolism*; D024101:Mitochondrial Proteins / Q000235:genetics / Q000378:metabolism*; D010935:Plant Diseases / Q000382:microbiology; D010937:Plant Growth Regulators / Q000378:metabolism*; D013312:Stress, Physiological
chemical_list: D029681:Arabidopsis Proteins; D005030:Ethylenes; D024101:Mitochondrial Proteins; D010937:Plant Growth Regulators; C000589711:SLO2 protein, Arabidopsis; D000040:Abscisic Acid; C036216:ethylene
keywords: ABA; Arabidopsis thaliana; PPR protein; RNA editing; SLO2; ethylene; mitochondria; plant stress; stress.