title: Luminogenic "clickable" lanthanide complexes for protein labeling.
abstract: Development of lanthanide-based luminescent "switch-on" systems via azide-alkyne [3+2] cycloaddition is described. We used these for non-specific protein labeling and as tags for specific and selective activity-based protein labeling.
authors.affiliation: Clermont-Université, Université Blaise Pascal and ENSCCF, Institut de Chimie de Clermont-Ferrand, F-63177 Aubière, France. arnaud.gautier@univ-bpclermont.fr.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Candelon
authors.forename: Niculina D
authors.initials: ND
authors.lastname: Hădade
authors.forename: Mihaela
authors.initials: M
authors.lastname: Matache
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Canet
authors.forename: Federico
authors.initials: F
authors.lastname: Cisnetti
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Funeriu
authors.forename: Lionel
authors.initials: L
authors.lastname: Nauton
authors.forename: Arnaud
authors.initials: A
authors.lastname: Gautier
mesh_terms: D000480:Alkynes / Q000737:chemistry; D000818:Animals; D001386:Azides / Q000737:chemistry; D002417:Cattle; D057930:Click Chemistry; D056831:Coordination Complexes / Q000737:chemistry*; D061565:Cycloaddition Reaction; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D010206:Papain / Q000737:chemistry / Q000378:metabolism; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D012710:Serum Albumin, Bovine / Q000737:chemistry / Q000378:metabolism; D013050:Spectrometry, Fluorescence
chemical_list: D000480:Alkynes; D001386:Azides; D056831:Coordination Complexes; D028581:Lanthanoid Series Elements; D011506:Proteins; D012710:Serum Albumin, Bovine; D010206:Papain