title: Microwave radiation induced oxidative stress, cognitive impairment and inflammation in brain of Fischer rats.
abstract: Public concerns over possible adverse effects of microwave radiation emitted by mobile phones on health are increasing. To evaluate the intensity of oxidative stress, cognitive impairment and inflammation in brain of Fischer rats exposed to microwave radiation, male Fischer-344 rats were exposed to 900 MHz microwave radiation (SAR = 5.953 x 10(-4) W/kg) and 1800 MHz microwave radiation (SAR = 5.835 x 10(-4) W/kg) for 30 days (2 h/day). Significant impairment in cognitive function and induction of oxidative stress in brain tissues of microwave exposed rats were observed in comparison with sham exposed groups. Further, significant increase in level of cytokines (IL-6 and TNF-alpha) was also observed following microwave exposure. Results of the present study indicated that increased oxidative stress due to microwave exposure may contribute to cognitive impairment and inflammation in brain.
authors.affiliation: Environmental Biochemistry and Molecular Biology Laboratory, Department of Biochemistry, University College of Medical Sciences & G.T.B. Hospital (University of Delhi), Dilshad Garden, Delhi 110 095, India.
authors.forename: Kanu
authors.initials: K
authors.lastname: Megha
authors.forename: Pravin Suryakantrao
authors.initials: PS
authors.lastname: Deshmukh
authors.forename: Basu Dev
authors.initials: BD
authors.lastname: Banerjee
authors.forename: Ashok Kumar
authors.initials: AK
authors.lastname: Tripathi
authors.forename: Mahesh Pandurang
authors.initials: MP
authors.lastname: Abegaonkar
mesh_terms: D000818:Animals; D003072:Cognition Disorders / Q000097:blood / Q000209:etiology*; D004307:Dose-Response Relationship, Radiation; D004660:Encephalitis / Q000097:blood / Q000209:etiology*; D005609:Free Radicals; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D018782:Maze Learning / Q000528:radiation effects; D008872:Microwaves / Q000009:adverse effects*; D018384:Oxidative Stress / Q000528:radiation effects*; D011833:Radiation Injuries, Experimental / Q000097:blood / Q000209:etiology*; D011897:Random Allocation; D051381:Rats; D011916:Rats, Inbred F344; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
chemical_list: D005609:Free Radicals; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha