title: [The role of endothelial dysfunction in progression of liver fibrosis and manifestation of сryoglobulinemia syndrome in patients with chronic hepatitis C].
abstract: The study of 78 patients with chronic hepatitis C is presented. It was found that emergence and progression of endothelium-dependent dysfunction of endothelium is combined with progression of liver fibrosis. The manifestation of clinical signs of the HCV-associated crioglobulinemia syndrome is registered in patients with stage F 3-4 liver fibrosis against the background of high concentration of the mixed cryoglobulins, rheumatoid factor of Ig M and the expressed endothelium-dependent dysfunction of endothelium.
authors.forename: Iu Iu
authors.initials: IuIu
authors.lastname: Riabokon'
mesh_terms: D000328:Adult; D000368:Aged; D003449:Cryoglobulinemia / Q000209:etiology / Q000503:physiopathology*; D018450:Disease Progression; D004730:Endothelium, Vascular / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D008103:Liver Cirrhosis / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013577:Syndrome; D014664:Vasodilation; D055815:Young Adult