title: Primary intrapulmonary malignant peripheral nerve sheath tumor mimicking lung cancer.
abstract: Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas originating from the cells constituting the nerve sheaths such as Schwann cells, perineural cells or fibroblasts. They represent approximately 5-10% of all soft tissue sarcomas. They have been rarely observed in the lung. We describe a rare case of primary lung MPNST in an elderly male patient, in which surgical approach has obtained a good control of the disease. Immuno-histochemical and molecular analyses have been required on the surgical specimen due to inadequate possibility of recognition through morphology alone.
authors.affiliation: Pathology Unit, National Cancer Institute, Pascale Foundation, Naples, Italy;
authors.forename: Elvira
authors.initials: E
authors.lastname: La Mantia
authors.forename: Renato
authors.initials: R
authors.lastname: Franco
authors.forename: Monica
authors.initials: M
authors.lastname: Cantile
authors.forename: Raffaele
authors.initials: R
authors.lastname: Rocco
authors.forename: Annarosaria
authors.initials: A
authors.lastname: De Chiara
authors.forename: Nicola
authors.initials: N
authors.lastname: Martucci
authors.forename: Gaetano
authors.initials: G
authors.lastname: Rocco
keywords: Malignant peripheral nerve sheath tumor; lung cancer; schwannoma