title: A new integrative conjugative element detected in Haitian isolates of Vibrio cholerae non-O1/non-O139.
abstract: The presence of SXT/R391-related integrating conjugative elements (ICEs) in Vibrio cholerae O1 and non-O1/non-O139 isolated from clinical and environmental samples in Haiti in 2010 was studied. The main finding of this work was the identification of the novel ICEVchHai2 among closely related V. cholerae non-O1/non-O139 clinical strains. The mosaic structure of this element confirms the role of ICEs as efficient recombination systems whereby new genetic material can be acquired and exchanged, according V. cholerae strains new accessory functions.
authors.affiliation: Maryland Pathogen Research Institute, University of Maryland, College Park, MD 20742, USA.
authors.forename: Daniela
authors.initials: D
authors.lastname: Ceccarelli
authors.affiliation: University College London Genetics Institute, University College London, London WC1E 6BT, UK.
authors.forename: Matteo
authors.initials: M
authors.lastname: Spagnoletti
authors.affiliation: Maryland Pathogen Research Institute, University of Maryland, College Park, MD 20742, USA.|CosmosID Inc., College Park, MD 20742, USA.
authors.forename: Nur A
authors.initials: NA
authors.lastname: Hasan
authors.affiliation: Department of Environmental Science and Technology, University of Maryland, College Park, MD 20742, USA.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Lansing
authors.affiliation: Maryland Pathogen Research Institute, University of Maryland, College Park, MD 20742, USA.|Maryland Institute of Applied Environmental Health, University of Maryland, College Park, MD 20742, USA.
authors.forename: Anwar
authors.initials: A
authors.lastname: Huq
authors.affiliation: Maryland Pathogen Research Institute, University of Maryland, College Park, MD 20742, USA.|CosmosID Inc., College Park, MD 20742, USA.|Maryland Institute of Applied Environmental Health, University of Maryland, College Park, MD 20742, USA.|Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
authors.forename: Rita R
authors.initials: RR
authors.lastname: Colwell
mesh_terms: D002771:Cholera / Q000382:microbiology; D004783:Environmental Microbiology; D019143:Evolution, Molecular; D006205:Haiti; D006801:Humans; D020071:Interspersed Repetitive Sequences; D011995:Recombination, Genetic; D044163:Vibrio cholerae non-O1 / Q000235:genetics* / Q000302:isolation & purification*
keywords: Haiti; Integrative conjugative elements; Non-O1/non-O139; Vibrio cholerae