title: [The role of immunomodulating therapy in the treatment and prevention of exacerbations of chronic cystitis].
abstract: The article presents the results of the examination and treatment of 60 women with chronic cystitis aged 20 to 80 years. The mean disease duration was 4,9 years (ranged from 6 months to 40 years). Immunomodulator Tilorone was included in the complex therapy of 30 patients of the main group. Besides the standard examination, immunological studies, including the definition of netrophil phagocytic rates in the patients were performed. It was revealed that the inclusion of immunomodulator in the treatment regimen of exacerbations of chronic cystitis contributes to an increase of index of activation of neutrophil phagocytic reserve, significant reduction in the frequency of exacerbations of the disease after the basic and preventive courses of treatment.
authors.forename: O S
authors.initials: OS
authors.lastname: Strel'tsova
authors.forename: V N
authors.initials: VN
authors.lastname: Krupin
authors.forename: G G
authors.initials: GG
authors.lastname: Rastorguev
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018856:Cystitis, Interstitial / Q000276:immunology / Q000473:pathology / Q000628:therapy*; D005260:Female; D006801:Humans; D007369:Interferon Inducers / Q000008:administration & dosage*; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology / Q000473:pathology; D010587:Phagocytosis / Q000187:drug effects / Q000276:immunology; D013994:Tilorone / Q000008:administration & dosage*
chemical_list: D007369:Interferon Inducers; D013994:Tilorone