title: Fabrication of graphene quantum dots and hexagonal boron nitride nanocomposites for fluorescent cell imaging.
abstract: Graphene quantum dots (GQDs) with green fluorescence were incorporated onto hexagonal boron nitride sheets (HBN) through electrostatic interaction by using poly(diallyldimethylammonium) (PDDA) as the bridge to fabricate the novel nanocomposites (HBN-GQDs). The HBN-GQDs nanocomposites exhibited strong green fluorescent property, high stability, water solubility, very low cytotoxicity on Hela cells. These properties make the HBN-GQDs nanocomposites as good candidate materials for biological applications. The results for the imaging of live cells indicated that the cell-penetrating HBN-GQDs could be a promising nanoprobe for intracellular imaging and therapeutic applications.
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Peng
authors.forename: Sheng
authors.initials: S
authors.lastname: Wang
authors.forename: Peng-Hui
authors.initials: PH
authors.lastname: Zhang
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Jiang
authors.forename: Jian-Jun
authors.initials: JJ
authors.lastname: Shi
authors.forename: Jun-Jie
authors.initials: JJ
authors.lastname: Zhu
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D003287:Contrast Media / Q000138:chemical synthesis; D005456:Fluorescent Dyes / Q000138:chemical synthesis; D006108:Graphite / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D008422:Materials Testing; D008856:Microscopy, Fluorescence / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry; D045663:Quantum Dots; D013347:Subcellular Fractions / Q000648:ultrastructure*
chemical_list: D001896:Boron Compounds; D003287:Contrast Media; D005456:Fluorescent Dyes; C017282:boron nitride; D006108:Graphite