title: Synthesis of silica-polymer core-shell nanoparticles by reversible addition-fragmentation chain transfer polymerization.
abstract: Hybrid nanoparticles hold great promise for a range of applications such as drug-delivery vectors or colloidal crystal self-assemblies. The challenge of preparing highly monodisperse particles for these applications has recently been overcome by using living radical polymerization techniques. In particular, the use of reversible addition-fragmentation chain transfer (RAFT), initiated from silica surfaces, yields well-defined particles from a range of precursor monomers resulting in nanoparticles of tailored sizes that are accessible via the rational selection of polymerization conditions. Furthermore, using RAFT allows post-polymerization modification to afford multifunctional, monodisperse, nanostructures under mild and non-stringent reaction conditions.
authors.affiliation: Key Centre for Polymers & Colloids, School of Chemistry, The University of Sydney, NSW 2006, Australia. sebastien.perrier@sydney.edu.au.
authors.forename: John
authors.initials: J
authors.lastname: Moraes
authors.forename: Kohji
authors.initials: K
authors.lastname: Ohno
authors.forename: Thomas
authors.initials: T
authors.lastname: Maschmeyer
authors.forename: Sébastien
authors.initials: S
authors.lastname: Perrier
mesh_terms: D003102:Colloids / Q000737:chemistry; D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry; D005609:Free Radicals / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry*; D058105:Polymerization; D011108:Polymers / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D003102:Colloids; D004337:Drug Carriers; D005609:Free Radicals; D011108:Polymers; D012822:Silicon Dioxide