title: [Consumption of medications, alcohol and smoking in pregnancy and assessment of teratogenic risks].
abstract: Medications, alcohol and smoking can cause fetal damage. A cross-sectional study was conducted with 326 mothers of the Fortaleza General Hospital to evaluate the use of drugs, alcohol and smoking during pregnancy and its relation to teratogenic potential in different population characteristics, between 2006 and 2007. Postpartum women who had their babies in the research site were included and those whose babies were not admitted as hospital inpatients were excluded. Chi-square tests and t-tests were used in the analysis, with a p value <0.05 considered significant. 96.6% of the mothers took medications (2.8 drugs/ pregnancy) and self-medication occurred in 11.3% of the cases. Single women took more drugs with high teratogenic potential (p=0.037). 11 cases of fetal malformation were observed, five of them were exposed to high teratogenic risks. Smoking occurred in 11.3% and alcohol use in 16%. Being single was found to be a risk factor for exposure to high teratogenic potential. Quality of prenatal care and other sociodemographic variables weren't related to exposure to teratogenic risks.
authors.affiliation: Universidade Estadual do Ceará (UECE), Fortaleza-CE, Brasil. bekinharocha@hotmail.com
authors.forename: Rebeca Silveira
authors.initials: RS
authors.lastname: Rocha
authors.forename: Samara Cavalcante
authors.initials: SC
authors.lastname: Bezerra
authors.forename: José Welington de Oliveira
authors.initials: JW
authors.lastname: Lima
authors.forename: Fabrício da Silva
authors.initials: Fda S
authors.lastname: Costa
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000453:epidemiology / Q000209:etiology; D000293:Adolescent; D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects / Q000453:epidemiology*; D001938:Brazil / Q000453:epidemiology; D000013:Congenital Abnormalities / Q000453:epidemiology* / Q000209:etiology; D003430:Cross-Sectional Studies; D004363:Drug Utilization / Q000706:statistics & numerical data*; D004522:Educational Status; D005260:Female; D006769:Hospitals, General / Q000706:statistics & numerical data; D006801:Humans; D007231:Infant, Newborn; D017533:Marital Status / Q000706:statistics & numerical data; D008875:Middle Aged; D004366:Nonprescription Drugs; D011247:Pregnancy / Q000706:statistics & numerical data*; D011295:Prenatal Care / Q000706:statistics & numerical data; D012307:Risk Factors; D012494:Sampling Studies; D012651:Self Medication / Q000706:statistics & numerical data; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D004366:Nonprescription Drugs