title: [The sexual peculiarities of aging changes in circannual rhythms of pineal gland, hypophysis, adrenal cortex and thymus functions in healthy subjects].
abstract: The interrelations of circannual rhythms of the functional state of pineal gland, hypophysis, adrenal cortex, thymus in healthy women and men from 20 to 79 years were studied. Fluctuations of melatonin, ACTH, cortisol and thymic serum factor, which were exchanged in aging (the season peaks of hormones and its acrophase) were found in blood of healthy 20-29 years old people. The changes of rhythmicity of indices were in male earlier (pineal gland and hypophysis over 30 years, thymus and adrenal cortex over 40 years) and more impressive than in women. The aging changes of pineal gland function's rhythm in healthy subjects have important role for changes of interrelations of circannual rhythms hypophysis, adrenal cortex and thymus.
authors.forename: I F
authors.initials: IF
authors.lastname: Labunets
mesh_terms: D000302:Adrenal Cortex / Q000502:physiology*; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D000368:Aged; D000375:Aging / Q000097:blood*; D015415:Biomarkers / Q000097:blood*; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008550:Melatonin / Q000097:blood; D008875:Middle Aged; D010870:Pineal Gland / Q000502:physiology*; D010902:Pituitary Gland / Q000502:physiology*; D012737:Sex Factors; D013935:Thymic Factor, Circulating / Q000378:metabolism; D013950:Thymus Gland / Q000502:physiology*; D055815:Young Adult
chemical_list: D015415:Biomarkers; D000324:Adrenocorticotropic Hormone; D013935:Thymic Factor, Circulating; D008550:Melatonin; D006854:Hydrocortisone