title: Sirtuin 3: A major control point for obesity-related metabolic diseases?
abstract: Obesity and obesity-related complications are epidemic issues currently plaguing much of the developed world with increasing associated morbidity, mortality, and economic burden. In this brief review, we discuss emerging evidence and remaining questions regarding the possible role for mitochondrial sirtuin 3 as a therapeutic target for the treatment of obesity-related metabolic diseases.
authors.affiliation: Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO USA.
authors.forename: Sean A
authors.initials: SA
authors.lastname: Newsom
authors.forename: Kristen E
authors.initials: KE
authors.lastname: Boyle
authors.forename: Jacob E
authors.initials: JE
authors.lastname: Friedman