title: Target delineation for radiosurgery of a small brain arteriovenous malformation using high-resolution contrast-enhanced cone beam CT.
abstract: Three years following endovascular embolization of a 3 mm ruptured arteriovenous malformation (AVM) of the left superior colliculus in a 42-year-old man, digital subtraction angiography showed continuous regrowth of the lesion. Thin-slice MRI acquired for treatment planning did not show the AVM nidus. The patient was brought back to the angiography suite for high-resolution contrast-enhanced cone beam CT (VasoCT) acquired using an angiographic c-arm system. The lesion and nidus were visualized with VasoCT. MRI, CT and VasoCT data were transferred to radiation planning software and mutually co-registered. The nidus was annotated for radiation on VasoCT data by an experienced neurointerventional radiologist and a dose/treatment plan was completed. Due to image registration, the treatment area could be directly adopted into the MRI and CT data. The AVM was completely obliterated 10 months following completion of the radiosurgery treatment.
authors.affiliation: Department of Radiology, University of Massachusetts, Worcester, Massachusetts, USA.
authors.forename: Imramsjah M J
authors.initials: IM
authors.lastname: van der Bom
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Gounis
authors.forename: Linda
authors.initials: L
authors.lastname: Ding
authors.forename: Anna Luisa
authors.initials: AL
authors.lastname: Kühn
authors.forename: David
authors.initials: D
authors.lastname: Goff
authors.forename: Ajit S
authors.initials: AS
authors.lastname: Puri
authors.forename: Ajay K
authors.initials: AK
authors.lastname: Wakhloo
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D002533:Cerebral Angiography; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000000981:diagnostic imaging* / Q000601:surgery*; D008297:Male; D011300:Preoperative Care / Q000379:methods; D016634:Radiosurgery; D016896:Treatment Outcome
keywords: Arteriovenous Malformation; CT; Technique