title: ARF1 and SAR1 GTPases in endomembrane trafficking in plants.
abstract: Small GTPases largely control membrane traffic, which is essential for the survival of all eukaryotes. Among the small GTP-binding proteins, ARF1 (ADP-ribosylation factor 1) and SAR1 (Secretion-Associated RAS super family 1) are commonly conserved among all eukaryotes with respect to both their functional and sequential characteristics. The ARF1 and SAR1 GTP-binding proteins are involved in the formation and budding of vesicles throughout plant endomembrane systems. ARF1 has been shown to play a critical role in COPI (Coat Protein Complex I)-mediated retrograde trafficking in eukaryotic systems, whereas SAR1 GTPases are involved in intracellular COPII-mediated protein trafficking from the ER to the Golgi apparatus. This review offers a summary of vesicular trafficking with an emphasis on the ARF1 and SAR1 expression patterns at early growth stages and in the de-etiolation process.
authors.affiliation: Plant Molecular Biology Laboratory, Genetic Engineering and Biotechnology Institute, Marmara Research Center, The Scientific and Technical Research Council of Turkey, TUBITAK, P.O. Box: 21, Gebze 41470, Kocaeli, Turkey. birsen.keskin@tubitak.gov.tr.
authors.forename: Birsen
authors.initials: B
authors.lastname: Cevher-Keskin
mesh_terms: D020823:ADP-Ribosylation Factor 1 / Q000378:metabolism*; D001692:Biological Transport; D004721:Endoplasmic Reticulum / Q000378:metabolism; D020558:GTP Phosphohydrolases / Q000378:metabolism*; D006056:Golgi Apparatus / Q000378:metabolism; D007425:Intracellular Membranes / Q000378:metabolism*; D008954:Models, Biological; D010940:Plant Proteins / Q000378:metabolism*; D050683:R-SNARE Proteins / Q000378:metabolism*
chemical_list: D010940:Plant Proteins; D050683:R-SNARE Proteins; D020558:GTP Phosphohydrolases; D020823:ADP-Ribosylation Factor 1