title: Decrease of uteroplacental blood flow after feticide during second-trimester pregnancy termination with complete placenta previa: quantitative analysis using contrast-enhanced ultrasound imaging.
abstract: Contrast enhanced ultrasound (CEUS) was used to quantify the dynamic changes in uteroplacental blood flow before and after the interruption of fetal villus circulation resulting from feticide during a second trimester pregnancy termination in a patient with complete placenta previa. Quantitative analysis was performed on time-intensity curves acquired 24 h before and 48 h and 120 h after feticide and demonstrated the persistence of utero-placental blood flow with a progressive and two-step reduction in intervillous space and uteroplacental blood flow. Our results suggest that placental blood flow reduction after interruption of fetal circulation is a progressive and delayed mechanism.
authors.affiliation: Unite de Medecine Foetale, Centre Olympe de Gouges, CHRU Bretonneau, Tours, France; INSERM UMR U930, Université de Tours, Tours, France. Electronic address: helene.bazin@etu.univ-tours.fr.
authors.forename: H
authors.initials: H
authors.lastname: Poret-Bazin
authors.forename: E G
authors.initials: EG
authors.lastname: Simon
authors.forename: A
authors.initials: A
authors.lastname: Bleuzen
authors.forename: P A
authors.initials: PA
authors.lastname: Dujardin
authors.forename: F
authors.initials: F
authors.lastname: Patat
authors.forename: F
authors.initials: F
authors.lastname: Perrotin
mesh_terms: D000025:Abortion, Eugenic; D000328:Adult; D003287:Contrast Media; D015536:Down-Regulation; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D010743:Phospholipids; D010923:Placenta Previa / Q000503:physiopathology*; D021041:Placental Circulation; D011184:Postoperative Period; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D013459:Sulfur Hexafluoride; D016896:Treatment Outcome; D016216:Ultrasonography, Prenatal; D014599:Uterus / Q000098:blood supply* / Q000000981:diagnostic imaging
chemical_list: D003287:Contrast Media; D010743:Phospholipids; C420843:contrast agent BR1; D013459:Sulfur Hexafluoride
keywords: Contrast enhanced ultrasound; Human; Placenta previa; Pregnancy termination; Uteroplacental perfusion