title: Markers of circulating breast cancer cells.
abstract: The detection of circulating tumor cells (CTC) aids in diagnosis of disease, prognosis, disease recurrence, and therapeutic response. The molecular aspects of metastasis are reviewed including its relevance in the identification and characterization of putative markers that may be useful in the detection thereof. Also discussed are methods for CTC enrichment using molecular strategies. The clinical application of CTC in the metastatic disease process is also summarized.
authors.affiliation: Departamento de Genética Médica, Unidad Médica de Alta Especialidad, Hospital de Gineco Obstetricia, No. 4, Dr. Luis Castelazo Ayala, IMSS, Colonia Tizapan San Angel, México, DF. astridkaryme2001@yahoo.com.mx
authors.forename: Eunice
authors.initials: E
authors.lastname: López-Muñoz
authors.forename: Manuel
authors.initials: M
authors.lastname: Méndez-Montes
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000097:blood*; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000473:pathology*; D002469:Cell Separation / Q000379:methods; D005260:Female; D005434:Flow Cytometry / Q000379:methods; D005821:Genetic Techniques; D006801:Humans; D009362:Neoplasm Metastasis / Q000175:diagnosis* / Q000473:pathology; D009360:Neoplastic Cells, Circulating / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor