title: Molecular Biology and Epidemiology of Hepatopancreatic parvovirus of Penaeid Shrimp.
abstract: Hepatopancreatic parvovirus (HPV) is one of the major shrimp parvovirus which is known to cause slow growth in penaeid shrimps. HPV has been found in wild and cultured penaeid shrimps throughout the world and there is high genetic variation among the different geographic isolates/host species. Given its high prevalence, wide distribution and ability to cause considerable economic loss in shrimp aquaculture industry, HPV deserves more attention than it has received. Till date, a total of four complete genome sequences of HPV have been reported in addition to a large number of partial sequences. HPV infection is seldom observed alone in epizootics and has occurred in multiple infections with other more pathogenic viruses and in most cases, heavy infections result in no visible inflammatory response. A great deal of information has accumulated in recent years on the clinical signs, geographical distribution, transmission and genetic diversity of HPV infection in shrimp aquaculture. However, the mechanism by which HPV enters the shrimp tissues and pathogenesis of virus is still unknown. To date, no effective prophylactic measures are available to reduce the infection in shrimps. To control and prevent HPV infection, considerable research efforts are on. This review provides information on current knowledge on HPV infection in penaeid shrimp aquaculture.
authors.affiliation: Department of Fishery Microbiology, College of Fisheries, Karnataka Veterinary, Animal and Fisheries Sciences University, Mangalore, 575 002 India.
authors.forename: Muhammed P
authors.initials: MP
authors.lastname: Safeena
authors.forename: Praveen
authors.initials: P
authors.lastname: Rai
authors.forename: Indrani
authors.initials: I
authors.lastname: Karunasagar
keywords: Diagnosis; HPV; PCR; Penaeid shrimps; PmoDNV