title: Endobronchial ultrasound-guided transbronchial needle aspiration in the mediastinal staging of non-small cell lung cancer: a meta-analysis.
abstract: In this article, we assessed the pooled sensitivity and specificity of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in studies during the last 10 years that have solely used EBUS-TBNA as a minimally invasive technique, with or without computed tomography or positron-emission tomography screening. The meta-analysis included 1,066 patients from 9 studies who underwent EBUS-TBNA. The results show EBUS-TBNA is a potential technique for the investigation, diagnosis, and staging of non-small cell lung cancer among patients with suspected lung cancer. It has excellent sensitivity, specificity, accuracy, positive predictive value, and negative predictive value. EBUS-TBNA is well tolerated and does not lead to complications in patients.
authors.affiliation: Department of Hematology-Oncology, Tianjin Medical University General Hospital, Tianjin, China.
authors.forename: Xifeng
authors.initials: X
authors.lastname: Dong
authors.affiliation: Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Xiaochun
authors.initials: X
authors.lastname: Qiu
authors.affiliation: Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Sbarro Institute for Cancer Research and Molecular Medicine, Center of Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania. Electronic address: jackjia2010@gmail.com.
authors.forename: Jack
authors.initials: J
authors.lastname: Jia
mesh_terms: D001999:Bronchoscopy; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging / Q000473:pathology*; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008482:Mediastinum; D009367:Neoplasm Staging / Q000379:methods; D012680:Sensitivity and Specificity
keywords: 10