title: Analysis of male aggressive and sexual behavior in mice.
abstract: Pheromone and odor signals play a pivotal role in male mouse reproductive behaviors, such as sexual and aggressive behavior. There are several methods used to assess male behaviors, each of which examines a unique aspect of the biological function of mice. There are two major ways of assessing male aggressive behavior in mice, one is using isolation-induced aggression, and the other is territorial aggression in pair-housed males. To analyze male sexual behavior, a female mouse that is hormone-primed with estradiol and progesterone is usually introduced into a male home range, and mounting, intromission, and ejaculation behaviors are observed for 1 h. Here, we summarize the detailed protocols for assessing male behaviors.
authors.affiliation: School of Veterinary Medical Sciences, Azabu University, Sagamihara, Japan.
authors.forename: Takefumi
authors.initials: T
authors.lastname: Kikusui
mesh_terms: D000374:Aggression / Q000502:physiology*; D000818:Animals; D005260:Female; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D010675:Pheromones / Q000378:metabolism*; D012726:Sexual Behavior, Animal / Q000502:physiology*; D013731:Territoriality; D014828:Vocalization, Animal / Q000502:physiology*
chemical_list: D010675:Pheromones