title: Outcomes of traumatic brain injury in Hong Kong: validation with the TRISS, CRASH, and IMPACT models.
abstract: We aimed to test prognostic models (the Trauma Injury Severity Score, International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury, and Corticosteroid Randomisation After Significant Head Injury models) for 14-day mortality, 6-month mortality, and 6-month unfavorable outcome in a cohort of trauma patients with traumatic brain injury (TBI) in Hong Kong. We analyzed 661 patients with significant TBI treated in a regional trauma centre in Hong Kong over a 3-year period. The discriminatory power of the models was assessed as the area under the receiver operating characteristic curve. One-sample t-tests were used to compare actual outcomes in the cohort against predicted outcomes. All three prognostic models were shown to have good discriminatory power and no significant systemic over-estimation or under-estimation. In conclusion, all three predictive models are applicable to eligible TBI patients in Hong Kong. These predictive models can be utilized to audit TBI management outcomes for trauma service development in the future.
authors.affiliation: Division of Neurosurgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong. Electronic address: georgewong@surgery.cuhk.edu.hk.
authors.forename: George Kwok Chu
authors.initials: GK
authors.lastname: Wong
authors.forename: Jeremy
authors.initials: J
authors.lastname: Teoh
authors.forename: Janice
authors.initials: J
authors.lastname: Yeung
authors.forename: Emily
authors.initials: E
authors.lastname: Chan
authors.forename: Eva
authors.initials: E
authors.lastname: Siu
authors.forename: Peter
authors.initials: P
authors.lastname: Woo
authors.forename: Timothy
authors.initials: T
authors.lastname: Rainer
authors.forename: Wai Sang
authors.initials: WS
authors.lastname: Poon
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001930:Brain Injuries / Q000175:diagnosis* / Q000401:mortality*; D005260:Female; D006723:Hong Kong; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D011379:Prognosis; D015599:Trauma Severity Indices
keywords: Mortality; Outcome; Prediction; Traumatic brain injury