title: [Prevalence of Cutaneous Reactivity to an Allergenic Extract of Mus musculus in Patients with Allergic Rhinitis and Asthma].
abstract: BACKGROUND
  A high prevalence of sensitization to antigen Mus musculus (mouse) in patients with allergic respiratory diseases has been reported worldwide.
  
  
  OBJECTIVE
  To determine the prevalence of skin reactivity to the Mus musculus antigen in patients with asthma and allergic rhinitis in the Department of Allergy and Clinical Immunology, Hospital Universitario de Puebla.
  
  
  METHODS
  We conducted a cross-sectional, observational, prospective and descriptive study in patients of both genders, from 2 to 58 years old. All patients were attending the hospital for the first time, in a period of 6 months with the diagnoses of asthma, allergic rhinitis, or both. Each patient underwent skin prick test with epithelial antigen Mus musculus. Data were analyzed with SPSS-Statistics software, version 18.
  
  
  RESULTS
  We included 110 patients, 50% were women, mean age was 24.1 years (SD 16.2); 92.7% were from urban areas and the rest from rural areas. The overall prevalence of skin reactivity to the antigen tested was 1.8%; corresponding to patients with allergic rhinitis 2.4% and the remaining subgroups showed no reactivity. One of the three patients with positive skin tests worked in an animal laboratory, exposed to Mus musculus.
  
  
  CONCLUSIONS
  We found a low prevalence of positive skin tests with mouse antigen. However, in patients with respiratory allergy symptoms and a strong exposure to mice or rodents we suggest to perform skin tests with mice allergen extracts.
authors.affiliation: Servicio de Alergia e InmunologÌa ClÌnica, Hospital Universitario de Puebla, BenemÈrita Universidad AutÛnoma de Puebla, Puebla, MÈxico. gengyny@yahoo.com.
authors.forename: Chrystopherson Gengyny
authors.initials: CG
authors.lastname: Caballero-López
authors.forename: Aida Inés
authors.initials: AI
authors.lastname: López-García
authors.forename: Oswaldo
authors.initials: O
authors.lastname: Arana-Muñoz
authors.forename: Marìa Socorro Yolanda
authors.initials: MS
authors.lastname: Carcaño-Pérez
authors.forename: Sergio
authors.initials: S
authors.lastname: Papaqui-Tapia
authors.forename: Erica Marisol
authors.initials: EM
authors.lastname: Martínez-Villegas
authors.forename: Guadalupe
authors.initials: G
authors.lastname: Morales-de-León
mesh_terms: D000818:Animals; D001249:Asthma / Q000453:epidemiology; D003430:Cross-Sectional Studies; D006801:Humans; D051379:Mice; D015995:Prevalence; D011446:Prospective Studies; D065631:Rhinitis, Allergic; D012882:Skin Tests