title: Does real-time elastography aid in differentiating canine splenic nodules?
abstract: Real-time elastography is a new ultrasonographic technology for measurement of tissue elasticity. Malignant lesions in the human breast, prostate, thyroid and lymph nodes show significantly reduced elasticity. The present study investigated the use of real-time elastography in the spleen of 22 dogs (8 benign and 6 malignant nodules, and 8 normal spleens) and results were compared to contrast-enhanced ultrasound findings. In summary, real-time elastography was neither able to differentiate benign from malignant splenic lesions, nor normal from diseased splenic tissue. No significant associations with contrast-enhanced ultrasound results were found. Real-time elastography, therefore, does not appear a useful tool for the differentiation of splenic nodules in the dog.
authors.affiliation: Clinic for Small Animal Surgery, University of Zurich, Switzerland.
authors.forename: D
authors.initials: D
authors.lastname: Alder
authors.forename: D
authors.initials: D
authors.lastname: Bass
authors.forename: M
authors.initials: M
authors.lastname: Spörri
authors.forename: P
authors.initials: P
authors.lastname: Kircher
authors.forename: S
authors.initials: S
authors.lastname: Ohlerth
mesh_terms: D000818:Animals; D044963:Biopsy, Fine-Needle / Q000662:veterinary; D016022:Case-Control Studies; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000000981:diagnostic imaging*; D004285:Dogs; D054459:Elasticity Imaging Techniques / Q000662:veterinary*; D005260:Female; D008297:Male; D011446:Prospective Studies; D013154:Spleen / Q000000981:diagnostic imaging* / Q000473:pathology; D013158:Splenic Diseases / Q000000981:diagnostic imaging / Q000662:veterinary; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging / Q000662:veterinary*