title: Fermented milk containing Lactobacillus GG alleviated DSS-induced colitis in mice and activated epidermal growth factor receptor and Akt signaling in intestinal epithelial cells.
abstract: Lactobacillus rhamnosus GG was assessed for its ability to alleviate DSS-induced colitis in mice and activate epidermal growth factor receptor and Akt signaling in intestinal epithelial cells. In this study mice were treated with DSS to induce colitis and they were given Lactobacillus GG fermented milk to assess the effect of probiotic on colitis. Lactobacillus GG fermented milk significantly reduced the colitis associated changes suggesting a protective effect against DSS induced colitis.
authors.affiliation: Technical Research Laboratory, Takanashi Milk Products Co., Ltd., Yokohama, Kanagawa, Japan.
authors.forename: Kazutoyo
authors.initials: K
authors.lastname: Yoda
authors.forename: Fang
authors.initials: F
authors.lastname: He
authors.forename: Kenji
authors.initials: K
authors.lastname: Miyazawa
authors.forename: Masaru
authors.initials: M
authors.lastname: Hiramatsu
authors.forename: Fang
authors.initials: F
authors.lastname: Yan
keywords: EGF receptor; Lactobacillus GG; colitis; fermented milk; intestinal epithelial cell