title: Fbxw7 hotspot mutations and human colon cancer: mechanistic insights from new mouse models.
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Grim
mesh_terms: D018256:Adenomatous Polyps / Q000235:genetics*; D000818:Animals; D014408:Biomarkers, Tumor / Q000235:genetics*; D018797:Cell Cycle Proteins / Q000235:genetics*; D015179:Colorectal Neoplasms / Q000235:genetics*; D044783:F-Box Proteins / Q000235:genetics*; D000073979:F-Box-WD Repeat-Containing Protein 7; D006801:Humans; D007417:Intestinal Polyps / Q000235:genetics*; D020125:Mutation, Missense; D044767:Ubiquitin-Protein Ligases / Q000235:genetics*
chemical_list: D014408:Biomarkers, Tumor; D018797:Cell Cycle Proteins; D044783:F-Box Proteins; D000073979:F-Box-WD Repeat-Containing Protein 7; C513273:FBXW7 protein, human; C513272:Fbxw7 protein, mouse; D044767:Ubiquitin-Protein Ligases
keywords: Basic Sciences; Cancer Genetics; Cell Biology; Colon Carcinogenesis; Colorectal Cancer Genes