title: [Nephrotoxicity due to iodine contrasts in computerized tomography studies of diabetic outpatients on metformin].
abstract: BACKGROUND
  To determine the incidence of contrast-induced nephropathy (CIN) among diabetic patients treated with Metformin who underwent computerized tomography (CT) scan with iodinated contrast media.
  
  
  METHODS
  Prospective study of diabetic patients enrolled in a lactic acidosis prevention protocol in whom clinical and analytical follow up after CT scan with intravenous contrast was performed.
  
  
  RESULTS
  In this study, 98 cases were collected. The incidence of CIN in diabetic patients without prior renal failure was 0%. In patients with previous renal failure the incidence of CIN was 4.7%.
  
  
  CONCLUSIONS
  The risk of CIN in diabetic patients with no renal failure undergoing intravenous contrast administration is minimal. Recommendations to stop Metformin to avoid lactic acidosis in patients undergoing intravenous contrast administration may be restricted to patients with abnormal renal function.
authors.affiliation: Servicio de Radiología, Complejo Hospitalario de Navarra, C/ Irunlarrea, 3 31008 Pamplona. hgomezhe@navarra.es
authors.forename: H
authors.initials: H
authors.lastname: Gómez Herrero
authors.forename: C
authors.initials: C
authors.lastname: De Arriba Villamor
authors.forename: M
authors.initials: M
authors.lastname: Buldain Parra
authors.forename: M
authors.initials: M
authors.lastname: Arraiza Sarasa
mesh_terms: D000368:Aged; D003287:Contrast Media / Q000009:adverse effects*; D003920:Diabetes Mellitus / Q000188:drug therapy; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D015994:Incidence; D017613:Iodine Compounds / Q000009:adverse effects*; D007674:Kidney Diseases / Q000139:chemically induced* / Q000453:epidemiology; D008297:Male; D008687:Metformin / Q000627:therapeutic use; D010045:Outpatients; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D007004:Hypoglycemic Agents; D017613:Iodine Compounds; D008687:Metformin