title: Is the lateral transpsoas approach feasible for the treatment of adult degenerative scoliosis?
abstract: BACKGROUND
  Lumbar degenerative scoliosis is a common condition in the elderly. Open traditional surgical approaches are associated with high-morbidity complication rates. Less invasive options may carry fewer risks in this patient population. A minimally disruptive lateral transpsoas retroperitoneal technique to accomplish interbody fusion was developed to avoid the morbidity of traditional open surgery, but this approach as an anterior stand-alone construction has not been reported yet for the treatment of adult degenerative scoliosis.
  
  
  OBJECTIVE
  We determined (1) the clinical outcomes (VAS scores for back and leg, Oswestry Disability Index), (2) the radiographic outcomes (Cobb angle, lumbar lordosis, sacral slope, high-grade subsidence, osseous fusion), and (3) the reoperation and complication rates in an older population undergoing this surgical approach.
  
  
  METHODS
  Between 2004 and 2008, 62 patients were treated surgically for adult degenerative scoliosis, of whom 46 (74%) were treated with stand-alone lateral lumbar interbody fusion; 11 of these (24%) were lost to followup before 24 months, leaving the records of 35 patients (nine men, 26 women; mean ± SD age, 68 ± 10 years) available for this retrospective review. General indications for this approach included neurogenic claudication and radicular symptoms with history of chronic low-back pain. A total of 107 levels were treated (mean, three; range, one to seven). Clinical and radiographic outcomes were assessed at a followup of 24 months.
  
  
  RESULTS
  Mean VAS back pain scores improved from 85 mm preoperatively to 27 mm at latest followup (p < 0.001). VAS leg pain scores improved from 91 mm to 24 mm (p < 0.001). Oswestry Disability Index scores improved from 51 to 29 (p < 0.001). Coronal alignment improved from Cobb angles of 21° to 12° (p < 0.001). Lumbar lordosis improved from 33° to 41° (p < 0.001). Sacral slope was enhanced from 28° to 35° (p < 0.001). Fusion rate was 84% at final evaluation. High-grade subsidence was seen in 10 patients (29%). Three patients (9%) needed further surgical intervention.
  
  
  CONCLUSIONS
  Use of the lateral approach achieved reasonable coronal and sagittal correction, as well as improvements in pain and function, in mild scoliotic deformities; however, subsidence was a concern, occurring in 29% of patients. Questions still remain regarding the need for additional supplementation or the use of wider cages to prevent subsidence.
  
  
  METHODS
  Level IV, therapeutic study. See Instructions for Authors for a complete description of levels of evidence.
authors.affiliation: Department of Minimally Invasive Spine Surgery, Instituto de Patologia da Coluna, Rua Vergueiro 1421, Sala 305, Torre Sul, 04101-000, São Paulo, SP, Brazil.
authors.forename: Carlos
authors.initials: C
authors.lastname: Castro
authors.forename: Leonardo
authors.initials: L
authors.lastname: Oliveira
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Amaral
authors.forename: Luis
authors.initials: L
authors.lastname: Marchi
authors.forename: Luiz
authors.initials: L
authors.lastname: Pimenta
mesh_terms: D000367:Age Factors; D000368:Aged; D004185:Disability Evaluation; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D010147:Pain Measurement; D011183:Postoperative Complications / Q000209:etiology / Q000601:surgery; D011859:Radiography; D012086:Reoperation; D012189:Retrospective Studies; D012600:Scoliosis / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D013123:Spinal Fusion / Q000009:adverse effects / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome