title: [An autopsy case of tension pneumothorax due to the rupture of intrapulmonary cavity by mucormycosis during treatment with a ventilator].
abstract: A 50-year-old man with chronic renal failure (hemodialysis treatment) and interstitial pneumonia (IP) was referred to our hospital for exacerbation of IP. We immediately administered a mechanical ventilation, broad spectrum antibiotics, steroid pulse therapy, and endoxan pulse therapy in the intensive care unit, but alveolar opacities became worse. Subsequently, an intrapulmonary cavity appeared in the left middle lung field on the chest X-ray and we also administered amphotericin B. However he died of tension pneumothorax on the tenth day of hospitalization. In an autopsy the rupture of the intrapulmonary cavity of the left S3 region was detected and we diagnosed as invasive pulmonary mucormycosis by Grocott stain of the cavitary lesion. We report a rare case that complicated by fatal tension pneumothorax during treatment with a ventilator in invasive pulmonary mucormycosis and review the literature.
authors.affiliation: Department of Respiratory Medicine, Seirei Yokohama Hosiptal, Japan.
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Nagakawa
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Igari
authors.forename: Kenji
authors.initials: K
authors.lastname: Konishi
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Kashizaki
authors.forename: Mayumi
authors.initials: M
authors.lastname: Aoyama
authors.forename: Akira
authors.initials: A
authors.lastname: Watanabe
authors.forename: Koichiro
authors.initials: K
authors.lastname: Tatsumi
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Kamei
mesh_terms: D001344:Autopsy; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications* / Q000628:therapy*; D011030:Pneumothorax / Q000209:etiology* / Q000473:pathology; D012421:Rupture; D012122:Ventilators, Mechanical / Q000009:adverse effects*