title: Preoperative oral use of Ibuprofen or dexamethasone may improve the anesthetic efficacy of an inferior alveolar nerve block in patients diagnosed with irreversible pulpitis.
abstract: BACKGROUND
  Effect of premedication with ibuprofen and dexamethasone on success rate of inferior alveolar nerve block for teeth with asymptomatic irreversible pulpitis: a randomized clinical trial. Shahi S, Moktari H, Rahimi S, Yavari HR, Narimani S, Abdolrahmi M, Nezafati S. J Endod 2013;39(2):160-2.
  
  
  METHODS
  John M. Nusstein, DDS, MS PURPOSE/QUESTION: To determine whether preoperative oral administration of ibuprofen (400 mg), dexamethasone (0.5 mg), or placebo (lactose) would improve the anesthetic success rate of an inferior alveolar nerve block in patients with molars diagnosed with asymptomatic irreversible pulpitis
  
  
  BACKGROUND
  University: Dental and Periodontal Research Center of Tabriz, Tabriz University of Medical Sciences, Tabriz, Iran
  
  
  METHODS
  Randomized controlled trial
  
  
  METHODS
  Level 2: Limited-quality, patient-oriented evidence
  
  
  METHODS
  Not applicable.
authors.affiliation: Division of Endodontics, The Ohio State University College of Dentistry, 305 W. 12th Ave., Columbus, OH 43210, USA. Electronic address: nusstein.1@osu.edu.
authors.forename: John M
authors.initials: JM
authors.lastname: Nusstein
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D003907:Dexamethasone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use*; D008297:Male; D008340:Mandibular Nerve; D009407:Nerve Block / Q000379:methods*; D011292:Premedication; D011671:Pulpitis / Q000503:physiopathology*
chemical_list: D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D003907:Dexamethasone; D007052:Ibuprofen