title: [The clinical significance of 1,3-beta-D glucanase detection in plasma to the diagnosis of fungal rhinosinusitis].
abstract: OBJECTIVE
  To investigate the clinical significance of 1,3-beta-D glucanase detection in plasma to the diagnosis of fungal rhinosinusitis.
  
  
  METHODS
  MB-80 rapid microorganism detection system was used to detect preoperative and postoperative 1,3-beta-D glucanase in plasma of 37 patients of fungal rhinosinusitis which were treated by endoscopic sinus surgery and confirmed by postoperative pathology. Blood samples of 47 patients who underwent endoscopic surgery(fungal rhinosinusitis excluded) were taken as control group.
  
  
  RESULTS
  1,3-beta-D glucanase content is more than 10 pg/ml in 34 cases of the fungal rhinosinusitis group,and every 1,3-beta-D glucanase content of 47 control cases is less than 10 pg/ml. Significant difference is found between case and control groups(chi2 = 72.6, P < 0.01).
  
  
  CONCLUSIONS
  1,3-beta-D glucanase detection in plasma is a simple,rapid diagnostic method of fungal rhinosinusitis.
authors.affiliation: Department of Otolaryngology, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Yang
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Bian
authors.forename: Bo
authors.initials: B
authors.lastname: Yu
authors.forename: Xin
authors.initials: X
authors.lastname: Hu
authors.forename: Haibo
authors.initials: H
authors.lastname: Zhang
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Cao
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D044644:Endo-1,3(4)-beta-Glucanase / Q000097:blood*; D005260:Female; D005658:Fungi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000097:blood / Q000175:diagnosis*; D012852:Sinusitis / Q000097:blood* / Q000175:diagnosis* / Q000382:microbiology; D055815:Young Adult
chemical_list: D044644:Endo-1,3(4)-beta-Glucanase