title: Ethanol extract of Moringa oliefera prevents in vitro glucose induced cataract on isolated goat eye lens.
abstract: OBJECTIVE
  The aim of current work was to evaluate in vitro anticataract potential of Moringa oliefera extract.
  
  
  METHODS
  Goat eye lenses were divided into 4 groups; Group served as control, Group II as toxic control, Group III and Group IV were incubated in extract (250 μg/ml and 500 μg/ml of extract of M. oliefera) Group II, III and IV were incubated in 55 mM glucose in artificial aqueous humor to induce lens opacification. Estimation of total, water soluble protein, catalase, glutathione and malondialdehyde along with photographic evaluation of lens was done.
  
  
  RESULTS
  Group II (toxic control) lenses showed high amount of MDA (Malondialdehyde), soluble, insoluble protein, decreased catalase and glutathione levels, while lenses treated with Moringa oliefera extract (Group III and Group IV) showed significant (FNx01 P < 0.05) reduction in MDA and increased level of catalase, glutathione, total and soluble protein.
  
  
  CONCLUSIONS
  Results of present findings suggest protective effect of Moringa oliefera in prevention of in vitro glucose induced cataract.
authors.forename: Raghvendra
authors.initials: R
authors.lastname: Kurmi
authors.affiliation: Department of Pharmacy, Shri Ram Institute of Technology, Jabalpur, Madhya Pradesh, India.
authors.forename: Aditya
authors.initials: A
authors.lastname: Ganeshpurkar
authors.forename: Divya
authors.initials: D
authors.lastname: Bansal
authors.forename: Abhishek
authors.initials: A
authors.lastname: Agnihotri
authors.forename: Nazneen
authors.initials: N
authors.lastname: Dubey
mesh_terms: D000818:Animals; D002386:Cataract / Q000139:chemically induced / Q000473:pathology / Q000517:prevention & control*; D004195:Disease Models, Animal; D000431:Ethanol / Q000494:pharmacology*; D005947:Glucose / Q000633:toxicity; D006041:Goats; D007908:Lens, Crystalline / Q000187:drug effects* / Q000473:pathology; D029588:Moringa oleifera; D010936:Plant Extracts / Q000627:therapeutic use*; D012997:Solvents / Q000494:pharmacology
chemical_list: D010936:Plant Extracts; D012997:Solvents; D000431:Ethanol; D005947:Glucose