title: [Charles Bonnet syndrome precipitated by brimonidine].
abstract: METHODS
  An 81-year-old woman with age-related macular degeneration and pseudoexfoliative glaucoma developed visual hallucinations (faces, flowers and frames) shortly after beginning brimonidine drops. Neurologic and psychiatric examination was normal. Visual hallucinations disappeared within 10 days after discontinuing the drug.
  
  
  CONCLUSIONS
  The Charles Bonnet syndrome (CBS) is characterised by complex visual hallucinations in elderly patients in the setting of significant visual impairment without any psychiatric symptoms. Awareness of CBS among ophthalmologist is essential. Clinicians should treat visual impairment and be aware of possible visual hallucinations in patients treated with brimonidine.
authors.affiliation: Unidad de Neurooftalmología, Hospital Clínico San Carlos, Madrid, España. rociogarciacatalan@gmail.com
authors.forename: M R
authors.initials: MR
authors.lastname: García-Catalán
authors.forename: P
authors.initials: P
authors.lastname: Arriola-Villalobos
authors.forename: E
authors.initials: E
authors.lastname: Santos-Bueso
authors.forename: J
authors.initials: J
authors.lastname: Gil-de-Bernabé
authors.forename: D
authors.initials: D
authors.lastname: Díaz-Valle
authors.forename: J M
authors.initials: JM
authors.lastname: Benítez-del-Castillo
authors.forename: J
authors.initials: J
authors.lastname: García-Sánchez
mesh_terms: D060433:Administration, Ophthalmic; D058647:Adrenergic alpha-2 Receptor Agonists / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D000369:Aged, 80 and over; D000068438:Brimonidine Tartrate; D017889:Exfoliation Syndrome / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006212:Hallucinations / Q000139:chemically induced* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D008268:Macular Degeneration / Q000150:complications* / Q000188:drug therapy; D009460:Neurologic Examination; D009778:Occipital Lobe / Q000503:physiopathology; D011183:Postoperative Complications / Q000188:drug therapy; D011810:Quinoxalines / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D013449:Sulfonamides / Q000627:therapeutic use; D013843:Thiazines / Q000627:therapeutic use; D014130:Trabeculectomy; D014792:Visual Acuity
chemical_list: D058647:Adrenergic alpha-2 Receptor Agonists; D011810:Quinoxalines; D013449:Sulfonamides; D013843:Thiazines; D000068438:Brimonidine Tartrate; C111827:brinzolamide
keywords: Advanced age; Agudeza visual; Alucinaciones visuales; Brimonidina; Brimonidine; Charles Bonnet syndrome; Edad avanzada; Síndrome de Charles Bonnet; Visual acuity; Visual hallucinations