title: Non-lyme tick-borne diseases: a neurological perspective.
abstract: Tick-borne diseases are prevalent throughout the world and present a diagnostic challenge owing to their nonspecific clinical symptoms. Many tick-borne diseases involve the central and peripheral nervous systems. Early diagnosis or at least suspicion of a tick-borne cause is necessary to institute early empiric treatment. After a brief review of tick biology, we present the most common tick-borne diseases. A brief discussion of epidemiology, the transmission route, and pathogenesis is followed by a discussion of the clinical manifestations, diagnosis and treatment options when available. The review emphasizes the infectious causes with a significant neurological manifestation.
authors.affiliation: Department of Neurology, Wayne State University, Detroit, MI 48201, USA. naseraji@med.wayne.edu
authors.forename: Navid
authors.initials: N
authors.lastname: Seraji-Bozorgzad
authors.forename: Alexandros C
authors.initials: AC
authors.lastname: Tselis
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D006801:Humans; D009422:Nervous System Diseases / Q000209:etiology* / Q000469:parasitology; D017282:Tick-Borne Diseases / Q000150:complications* / Q000453:epidemiology*; D013987:Ticks / Q000472:pathogenicity / Q000502:physiology