title: Updates in diverticular disease.
abstract: Diverticulosis and its major complications, diverticulitis and diverticular bleeding, are increasingly common indications for hospitalization and outpatient visits. Recent publications in the field of diverticular disease have challenged long-standing disease concepts and management strategies. This article will highlight studies which have helped to clarify the contribution of genetic factors, fiber consumption and medication use to the development of diverticular disease, the role of antibiotics in the treatment of acute diverticulitis, and the association between diverticulitis, irritable bowel syndrome, and colon cancer.
authors.affiliation: Department of Medicine, Division of Gastroenterology, University of Washington, Seattle, WA 98105, USA. atempleton@medicine.washington.edu
authors.forename: Adam W
authors.initials: AW
authors.lastname: Templeton
authors.forename: Lisa L
authors.initials: LL
authors.lastname: Strate
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D003110:Colonic Neoplasms / Q000209:etiology; D004043:Dietary Fiber / Q000008:administration & dosage; D004238:Diverticulitis / Q000188:drug therapy / Q000209:etiology*; D004241:Diverticulum, Colon / Q000209:etiology*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D020022:Genetic Predisposition to Disease; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000209:etiology; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004043:Dietary Fiber