title: From perception to attenuation: auxin signalling and responses.
abstract: The plant hormone auxin is essential for growth, development, and responses to environmental factors. Recently, Auxin Binding Protein 1 was shown to mediate non-transcriptional auxin signalling at the cell periphery. This has provoked reexamination of the paradigm that all auxin perception is intracellular and is mediated by the TIR1/AFB-Aux/IAA co-receptors for which auxin functions as a concentration-dependent molecular glue. Further, another F-box protein, SKP2a, was shown to bind auxin in the same way as TIR1/AFB, which provides a link to the role of auxin in the cell cycle. New work on auxin signalling and homeostasis include D6 PROTEIN KINASE activation of PINFORMED (PIN) auxin carriers, ROP-GTPase mediation of PIN localization, endoplasmic reticulum localization PIN and PIN-LIKES auxin carriers, and auxin biosynthesis and metabolism.
authors.affiliation: Department of Environmental Science and Technology, University of Maryland, 5138 Plant Science Building, College Park, MD 20742, USA; Department of Plant Science and Landscape Architecture, University of Maryland, 5138 Plant Science Building, College Park, MD 20742, USA. Electronic address: wapeer@umd.edu.
authors.forename: Wendy Ann
authors.initials: WA
authors.lastname: Peer
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D006706:Homeostasis; D007210:Indoleacetic Acids / Q000378:metabolism*; D008024:Ligands; D008954:Models, Biological; D010937:Plant Growth Regulators / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D029681:Arabidopsis Proteins; D007210:Indoleacetic Acids; D008024:Ligands; D010937:Plant Growth Regulators