title: [Combined choroidal biopsy and cytology for diagnosis of intraocular tumour].
abstract: METHODS
  No intraocular biopsy technique is free of risk and all have the possibility of giving false negatives due to the difficulty in obtaining a sufficient sample. A modified chorioretinal biopsy was performed on a patient with suspected choroidal melanoma after negative biopsy with 25G vitrectomy. In addition to removing a solid fragment of tumor material using bimanual surgery, material from the lesion was obtained with the vitreotome to perform cytology, which confirmed the diagnosis of melanoma.
  
  
  CONCLUSIONS
  Cytology obtained through the vitreotome in association with removing a solid sample of the choroidal lesion may improve the efficiency of intraocular biopsy.
authors.affiliation: Hospital Clínico Universitario de Valladolid, Universidad de Valladolid, Valladolid, España. annasalapuigdollers@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Sala-Puigdollers
authors.forename: E
authors.initials: E
authors.lastname: Rodríguez-de la Rúa
authors.forename: M A
authors.initials: MA
authors.lastname: Saornil
authors.forename: C
authors.initials: C
authors.lastname: García-Álvarez
authors.forename: E
authors.initials: E
authors.lastname: García-Lagarto
authors.forename: Y
authors.initials: Y
authors.lastname: Ovelar Arribas
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001707:Biopsy, Needle / Q000295:instrumentation / Q000379:methods*; D002829:Choroid / Q000473:pathology*; D002830:Choroid Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003930:Diabetic Retinopathy / Q000150:complications / Q000601:surgery; D015353:Eye Enucleation; D005260:Female; D006801:Humans; D017075:Laser Coagulation; D008545:Melanoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D065006:Papanicolaou Test; D014463:Ultrasonography; D014604:Uveal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014821:Vitrectomy; D000098943:Uveal Melanoma
chemical_list: D014408:Biomarkers, Tumor
keywords: Biopsia intraocular; Choroidal melanoma; Citología; Cytology; Intraocular biopsy; Intraocular tumor; Melanoma de coroides; Tumor intraocular; Vitrectomy; Vitrectomía