title: Facile synthesis of dibranched conjugated dienes via palladium-catalyzed oxidative coupling of N-tosylhydrazones.
abstract: A facile and highly regioselective Pd-catalyzed oxidative coupling of N-tosylhydrazones providing efficient access to 2,3-disubstituted-1,3-butadienes has been developed. This process features readily available starting materials and mild reaction conditions. Further transformations of the obtained dibranched 1,3-dienes, through Diels-Alder reactions and indene synthesis, are also demonstrated, which reveal their great potential for synthetic utility.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China. jianghf@scut.edu.cn.
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
authors.forename: Li
authors.initials: L
authors.lastname: He
authors.forename: Xianwei
authors.initials: X
authors.lastname: Li
authors.forename: Huoji
authors.initials: H
authors.lastname: Chen
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.forename: Wei
authors.initials: W
authors.lastname: Fu
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D002070:Butadienes / Q000737:chemistry; D002384:Catalysis; D061565:Cycloaddition Reaction; D006835:Hydrazones / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry; D058451:Oxidative Coupling; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D002070:Butadienes; D006835:Hydrazones; C030011:carbene; D010165:Palladium; D008697:Methane