title: Epidemiology, prevention, and control of the number one foodborne illness: human norovirus.
abstract: Human norovirus (NoV) is the number one cause of foodborne illness. Despite tremendous research efforts, human NoV is still poorly understood and understudied. There is no effective measure to eliminate this virus from food and the environment. Future research efforts should focus on developing: (1) an efficient cell culture system and a robust animal model, (2) rapid and sensitive detection methods, (3) novel sanitizers and control interventions, and (4) vaccines and antiviral drugs. Furthermore, there is an urgent need to build multidisciplinary and multi-institutional teams to combat this important biodefense agent.
authors.affiliation: Department of Food Science and Technology, College of Food, Agricultural, and Environmental Sciences, The Ohio State University, 110 Parker Food Science and Technology Building, 2015 Fyffe Road, Columbus, OH 43210, USA.
authors.forename: Erin
authors.initials: E
authors.lastname: Dicaprio
authors.forename: Yuanmei
authors.initials: Y
authors.lastname: Ma
authors.forename: John
authors.initials: J
authors.lastname: Hughes
authors.forename: Jianrong
authors.initials: J
authors.lastname: Li
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D017250:Caliciviridae Infections / Q000453:epidemiology / Q000517:prevention & control / Q000821:virology; D005517:Foodborne Diseases / Q000453:epidemiology / Q000517:prevention & control / Q000821:virology; D006801:Humans; D029322:Norovirus / Q000472:pathogenicity; D014765:Viral Vaccines / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D000998:Antiviral Agents; D014765:Viral Vaccines
keywords: Acute gastroenteritis; Detection methods; Epidemiology; Foodborne illness; Human norovirus; Prevention and control strategies; Vaccine development