title: Carbamazepine-induced DRESS syndrome in a child: rapid response to pulsed corticosteroids.
abstract: DRESS syndrome is an idiosyncratic reaction to drugs, which can occur in both adults and children. To date there is no agreed upon criteria for its diagnosis; there is even less consensus on its management. We report the case of a 14- year-old boy with carbamazepine induced DRESS syndrome, predominantly involving the liver. He responded rapidly to high dose pulsed intravenous corticosteroids.
authors.affiliation: Queensland Institute of Dermatology Greenslopes.
authors.forename: Paul
authors.initials: P
authors.lastname: Teng
authors.forename: Boon
authors.initials: B
authors.lastname: Tan
mesh_terms: D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D001930:Brain Injuries / Q000150:complications; D002220:Carbamazepine / Q000009:adverse effects* / Q000627:therapeutic use; D063926:Drug Hypersensitivity Syndrome / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D004359:Drug Therapy, Combination; D004643:Emollients / Q000627:therapeutic use*; D005446:Fluocinolone Acetonide / Q000008:administration & dosage / Q000627:therapeutic use*; D006529:Hepatomegaly / Q000139:chemically induced / Q000188:drug therapy; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D008899:Mineral Oil / Q000627:therapeutic use*; D020551:Pulse Therapy, Drug; D012640:Seizures / Q000188:drug therapy / Q000209:etiology; D012867:Skin / Q000473:pathology; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use*
chemical_list: D000893:Anti-Inflammatory Agents; D000927:Anticonvulsants; D004643:Emollients; D005446:Fluocinolone Acetonide; D002220:Carbamazepine; D014580:Ursodeoxycholic Acid; D008899:Mineral Oil; D008775:Methylprednisolone