title: [Clinical factors of pulmonary tuberculosis in non-tuberculosis wards and its incidence among contact patients and healthcare workers in our hospital using QuantiFERON GOLD testing].
abstract: OBJECTIVE
  In our hospital, we analyzed the clinical factors of pulmonary tuberculosis (TB) diagnosed in non-TB wards and the incidence of TB infection among contact patients and healthcare workers (HCWs) using QuantiFERON-TB GOLD (QFT) testing.
  
  
  METHODS
  This study included 16 patients who were diagnosed with pulmonary TB in non-TB wards in our hospital from January 2008 to May 2011. Eight contact patients and 120 HCWs were also enrolled.
  
  
  RESULTS
  The 16 TB patients comprised 11 men (77.7 years) and 5 women (74.4 years). Among them, only 9 patients exhibited positive results for Mycobacterium tuberculosis after the first acid-fast bacterial examination; the other 7 patients presented positive results only after the second or third examinations. Moreover, there were 3 cases of positive Mycobacterium avium samples in the first acid-fast bacterial examination. Among 16 pulmonary Mycobacterium tuberculosis cases, 8 were sputum smear and culture positive, 7 were sputum smear negative and culture positive, and 1 was sputum smear and culture negative. Moreover, 17 days had elapsed from the time of admission to the non-TB ward to diagnosis. TB contact examination revealed that QFT results for 2 HCWs changed from negative to positive.
  
  
  CONCLUSIONS
  We suspected pulmonary aspergillosis or old TB when presented with cases with a history of TB. Moreover, we believe that the periods from admission to diagnosis were delayed when the first acid-fast bacterial sputum examination was negative or showed non-tuberculous mycobacteria.
authors.affiliation: Department of Respiratory Medicine, Fukujuji Hospital, Japan Anti-Tuberculosis Association (JATA), 3-1-24, Matsuyama, Kiyose-shi, Tokyo 204-8522 Japan. okumuram@fukujuji.org
authors.forename: Masao
authors.initials: M
authors.lastname: Okumura
authors.forename: Atsuko
authors.initials: A
authors.lastname: Satoh
authors.forename: Takashi
authors.initials: T
authors.lastname: Yoshiyama
authors.forename: Hideki
authors.initials: H
authors.lastname: Yanai
authors.forename: Yuka
authors.initials: Y
authors.lastname: Sasaki
authors.forename: Shoji
authors.initials: S
authors.lastname: Kudoh
authors.forename: Hideo
authors.initials: H
authors.lastname: Ogata
mesh_terms: D000368:Aged; D003428:Cross Infection; D005260:Female; D006801:Humans; D017757:Infectious Disease Transmission, Professional-to-Patient; D059425:Interferon-gamma Release Tests; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000635:transmission*