title: Epstein-Barr virus-associated enteropathy as a complication of infectious mononucleosis mimicking peripheral T-cell lymphoma.
abstract: A 32-year-old man presented with a fever. A laboratory examination detected atypical lymphocytes and liver enzyme elevation. The serological tests for Epstein-Barr virus (EBV) were consistent with an acute infection pattern. Computed tomograpy showed bowel wall thickening, and colonoscopy revealed numerous ulcerations. The histological findings from the biopsy specimens from the colon were consistent with peripheral T-cell lymphoma (PTCL), and in situ hybridization detected EBER-1 in the atypical lymphocytes. Because his clinical and endoscopic abnormalities improved without medication, we diagnosed the patient with EBV-associated enteropathy. We herein report a rare case of EBV-associated enteropathy that required careful differentiation from PTCL.
authors.affiliation: Department of Hematology, National Cancer Center Hospital, Japan.
authors.forename: Shinobu
authors.initials: S
authors.lastname: Tamura
authors.forename: Dai
authors.initials: D
authors.lastname: Maruyama
authors.forename: Akiko
authors.initials: A
authors.lastname: Miyagi Maeshima
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Taniguchi
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Kakugawa
authors.forename: Masakazu
authors.initials: M
authors.lastname: Mori
authors.forename: Teruhisa
authors.initials: T
authors.lastname: Azuma
authors.forename: Sung-Won
authors.initials: SW
authors.lastname: Kim
authors.forename: Takashi
authors.initials: T
authors.lastname: Watanabe
authors.forename: Yukio
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Kensei
authors.initials: K
authors.lastname: Tobinai
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D020031:Epstein-Barr Virus Infections / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications / Q000175:diagnosis*; D016411:Lymphoma, T-Cell, Peripheral / Q000150:complications / Q000175:diagnosis*; D008297:Male