title: Preventing neurovascular invasion in desmoid tumors.
abstract: Desmoid tumors or aggressive fibromatoses are rare, non-encapsulated, infiltrative and locally aggressive tumors originating from deep musculo-aponeurotic structures. Traditionally, preferred treatment method for desmoid tumors is wide local excision. Depending on the side and type of resection, the reported local recurrence rates range from 15 to 77%. Similarly, in our institution there is a significant recurrence rate (24%) in patients who underwent surgery for desmoid tumor. After several recurrences, amputation may be inevitable following repeating vascular and nerve reconstructions. There is a need for a nonviable barrier in order to prevent the invasion of the viable tumor to the neurovascular structures which are also viable tissues. Depending on this need, we present two cases that we used synthetic vascular graft in their operations to cover neurovascular structures in order to prevent tumor invasion. For patients who are not suitable for radiotherapy and the neurovascular structures need to be secured because of the risk of local recurrence, this method can prevent possible future invasion of vessels and nerves.
authors.affiliation: Department of Orthopaedics and Traumatology, İstanbul Faculty of Medicine, İstanbul University, İstanbul, Turkey.
authors.forename: Harzem
authors.initials: H
authors.lastname: Özger
authors.forename: Okan
authors.initials: O
authors.lastname: Özkunt
authors.forename: Turgut
authors.initials: T
authors.lastname: Akgül
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Sağlam
mesh_terms: D000293:Adolescent; D001807:Blood Vessel Prosthesis; D002648:Child; D005260:Female; D018222:Desmoid Tumors / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness / Q000517:prevention & control*; D010524:Peripheral Nervous System Neoplasms / Q000473:pathology / Q000517:prevention & control*; D019651:Plastic Surgery Procedures / Q000379:methods*; D019043:Vascular Neoplasms / Q000473:pathology / Q000517:prevention & control*