title: Unusual cause of neuropathy: extensive dural spread of primary cervical osteosarcoma.
abstract: We report a very rare case of a high grade osteosarcoma of the cervical spine in a 62-year-old woman. She presented with a relatively short history of a swelling in the posterior neck and cervical lymphadenopathy. This was associated with hoarseness of the voice, significant weight loss, and right upper arm radicular symptoms initially, progressing to paraplegia. Based on MR and CT imaging of the neck and an excision biopsy of an enlarged right supraclavicular lymph node, the histology revealed a high grade primary osteosarcoma of the cervical spine.
authors.affiliation: Department of Orthopaedic Surgery, Hospital Tuanku Ja'afar , Seremban ; Cancer Research Center, Institute for Medical Research (IMR) , Kuala Lumpur.
authors.forename: Stephen N
authors.initials: SN
authors.lastname: Ponnampalam
authors.forename: Wilkinson Yj
authors.initials: WY
authors.lastname: Tan
authors.forename: Nayyer Naveed
authors.initials: NN
authors.lastname: Wazir
authors.forename: John
authors.initials: J
authors.lastname: George
keywords: Osteosarcoma; metastasis; paraplegia