title: Nitinol stents with polymer-free paclitaxel coating for stenosis of failing infrainguinal bypass grafts.
abstract: OBJECTIVE
  This study was designed to investigate the immediate and one-year outcomes of polymer-free paclitaxel coated drug-eluting stent (DES) implantation in a consecutive series of patients presenting with stenosis of infrainguinal bypass grafts.
  
  
  METHODS
  Between January 2011 and January 2012, 11 patients with failing infrainguinal bypass grafts were treated in two institutions. Clinical status and Duplex scan parameters were recorded at baseline and over a follow-up period of one year.
  
  
  RESULTS
  DES implantation was successfully performed in all patients. Ten patients received a single stent and one patient received two stents. At one year, one patient showed total bypass graft occlusion (9%). In all the remaining patients, Duplex scan examination documented patency of the treated grafts.
  
  
  CONCLUSIONS
  DES implantation in failing infrainguinal bypass grafts can be safely performed and provides satisfactory clinical outcomes. The patency rate of 91% favourably compares with those obtained with other endovascular treatments such as plain balloon or cutting balloon angioplasty.
authors.affiliation: Cardiovascular Department, Multimedica IRCCS, Sesto San Giovanni, Milan, Italy - flavio.airoldi@multimedica.it.
authors.forename: F
authors.initials: F
authors.lastname: Airoldi
authors.forename: G
authors.initials: G
authors.lastname: Baldino
authors.forename: P
authors.initials: P
authors.lastname: Mortola
authors.forename: S
authors.initials: S
authors.lastname: Losa
authors.forename: G
authors.initials: G
authors.lastname: Clerici
authors.forename: D
authors.initials: D
authors.lastname: Tavano
authors.forename: A
authors.initials: A
authors.lastname: Latib
authors.forename: A
authors.initials: A
authors.lastname: Gori
authors.forename: E
authors.initials: E
authors.lastname: Faglia
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000497:Alloys; D000800:Angioplasty, Balloon / Q000009:adverse effects / Q000295:instrumentation*; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation*; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D003251:Constriction, Pathologic; D054855:Drug-Eluting Stents; D005260:Female; D006083:Graft Occlusion, Vascular / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007558:Italy; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage*; D011474:Prosthesis Design; D011475:Prosthesis Failure; D013997:Time Factors; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex; D014654:Vascular Patency
chemical_list: D000497:Alloys; D002317:Cardiovascular Agents; C013616:nitinol; D017239:Paclitaxel