title: Prevalence and molecular typing of oxacillin-susceptible mecA-positive Staphylococcus aureus from multiple hospitals in China.
abstract: Among 1588 non-duplicated Staphylococcus aureus isolates from 10 cities in China, 60 isolates were susceptible to oxacillin (MIC50: 1 μg/mL; MIC90: 2 μg/mL) but were mecA-positive. Twenty-one spa and 5 staphylococcal cassette chromosome mec (SCCmec) types were detected, and combined with multilocus sequence typing method, ST59-t437-SCCmecIV/V was the predominant clone (26.7%, 16/60).
authors.affiliation: Department of Clinical Laboratory, Peking University People's Hospital, Beijing 100044, China.
authors.forename: Wenqiang
authors.initials: W
authors.lastname: He
authors.forename: Hongbin
authors.initials: H
authors.lastname: Chen
authors.forename: Chunjiang
authors.initials: C
authors.lastname: Zhao
authors.forename: Feifei
authors.initials: F
authors.lastname: Zhang
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics*; D002681:China / Q000453:epidemiology; D006761:Hospitals; D006801:Humans; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D058889:Molecular Typing; D010068:Oxacillin / Q000494:pharmacology*; D046915:Penicillin-Binding Proteins; D015995:Prevalence; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013205:Staphylococcal Protein A / Q000235:genetics; D013211:Staphylococcus aureus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D046915:Penicillin-Binding Proteins; D013205:Staphylococcal Protein A; C487789:mecA protein, Staphylococcus aureus; D010068:Oxacillin
keywords: Oxacillin; Staphylococcus aureus; mecA