title: [Alzheimer's disease and geriatric eye diseases in the aspect of amyloid genesis].
abstract: Geriatric eye diseases (age-related macular regeneration, pseudoexfoliation syndrome, pseudoexfoliative glaucoma, senile cataract) are one of the most important problems of modern ophthalmology. Meanwhile, the treatment of these diseases continues to be primarily empirically based for lack of not only valid data on their etiology, but even consensus of opinion on their pathogenesis. This review gives the current views on the commonness of the etiopathogenetic and morphological manifestations of Alzheimer's disease and age-related eye diseases in the aspect of amyloid genesis. This approach is a promising attempt to specify the mechanisms responsible for the occurrence and development of neurodegenerative diseases, their markers, and new perspectives in their treatment.
authors.forename: V V
authors.initials: VV
authors.lastname: Ermilov
authors.forename: I N
authors.initials: IN
authors.lastname: Tiurenkov
authors.forename: A A
authors.initials: AA
authors.lastname: Nesterova
authors.forename: V A
authors.initials: VA
authors.lastname: Zagrebin
mesh_terms: D000375:Aging / Q000378:metabolism / Q000473:pathology; D000544:Alzheimer Disease / Q000150:complications / Q000378:metabolism / Q000473:pathology / Q000628:therapy; D000682:Amyloid / Q000378:metabolism*; D005128:Eye Diseases / Q000209:etiology / Q000378:metabolism / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D000682:Amyloid