title: Mimicking the binding and unbinding of Fe3+ with transferrin using a single biomimetic nanochannel.
abstract: A new type of apo-Tf functionalized nanochannel is developed to achieve the specific and selective binding and unbinding of Fe(3+) in a multiple and reversible manner via a protein-conformation-gating mechanism. This ion-responsive biomimetic nanochannel provides a simple, robust, and promising model for studying other biological processes.
authors.affiliation: Department of Chemical and Biomolecular Engineering, The University of Akron, Akron, Ohio 44325, USA. zhengj@uakron.edu.
authors.forename: Chao
authors.initials: C
authors.lastname: Zhao
authors.forename: Xiaosi
authors.initials: X
authors.lastname: Li
authors.forename: Lingyan
authors.initials: L
authors.lastname: Li
authors.forename: Xiong
authors.initials: X
authors.lastname: Gong
authors.forename: Yung
authors.initials: Y
authors.lastname: Chang
authors.forename: Jie
authors.initials: J
authors.lastname: Zheng
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry / Q000378:metabolism*; D005290:Ferric Compounds / Q000737:chemistry / Q000378:metabolism*; D007477:Ions / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry*; D011485:Protein Binding; D014168:Transferrin / Q000737:chemistry / Q000378:metabolism*
chemical_list: D005290:Ferric Compounds; D007477:Ions; D014168:Transferrin