title: Applications of ZnO nanoflowers as antimicrobial agents for Escherichia coli and enzyme-free glucose sensor.
abstract: Well-crystalline ZnO nanoflowers were prepared by a facile solution process and their applications as an antimicrobial agent against Escherichia coli and enzyme-free glucose sensor have been studied. The morphological, structural, compositional, and optical properties of ZnO nanoflowers were characterized by various techniques, which confirmed the well-crystalline wurtzite hexagonal phase. The minimum inhibitory concentration of ZnO nanoflowers for inhibiting the growth of Escherichia coli was found to be 25 microg/ml. ZnO nanoflowers were also tested as an efficient electron mediator for the fabrication of highly sensitive non-enzymatic glucose sensor, which exhibited a high sensitivity of -411 microA M(-1) cm(-2) and detection limit of -1.25 mM with a quick response time of -10.0 s. The presented studies showed that ZnO nanomaterials can be efficiently used as an antimicrobial agent and a highly sensitive non-enzymatic glucose sensor.
authors.affiliation: Promising Centre for Sensors and Electronic Devices, Najran University, Najran 11001, Kingdom of Saudi Arabia. ahmadumar786@gmail.com
authors.forename: Ahmad
authors.initials: A
authors.lastname: Umar
authors.forename: M S
authors.initials: MS
authors.lastname: Chauhan
authors.forename: S
authors.initials: S
authors.lastname: Chauhan
authors.forename: R
authors.initials: R
authors.lastname: Kumar
authors.forename: P
authors.initials: P
authors.lastname: Sharma
authors.forename: Kirti Janghu
authors.initials: KJ
authors.lastname: Tomar
authors.forename: R
authors.initials: R
authors.lastname: Wahab
authors.forename: A
authors.initials: A
authors.lastname: Al-Hajry
authors.forename: Dilbag
authors.initials: D
authors.lastname: Singh
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000737:chemistry; D015374:Biosensing Techniques / Q000295:instrumentation*; D002470:Cell Survival / Q000187:drug effects; D003217:Conductometry / Q000295:instrumentation; D004867:Equipment Design; D019544:Equipment Failure Analysis; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects*; D005947:Glucose / Q000032:analysis* / Q000737:chemistry; D005949:Glucose Oxidase; D008422:Materials Testing; D053758:Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D015034:Zinc Oxide / Q000008:administration & dosage* / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D005949:Glucose Oxidase; D005947:Glucose; D015034:Zinc Oxide