title: [Characteristics of cell-mediated and humoral components of the immune response in the children presenting with chronic adenoiditis].
abstract: The objective of the present study was to determine the magnitude of characteristics of immunity and estimate the immunological status of the children presenting with chronic adenoiditis (CA) at the stage of remission. The valid sample (n=158) was used to analyse the blood cellular spectrum and humoral characteristics in the children at the age from 2.5 to 10 years residing in the city of Krasnoyarsk. It was shown that the development of CA was associated with the activation of non-specific protective factors and consistent with the general physiological patterns. The total T-lymphocyte population significantly increased which excluded the T-cellular immunodepressive state. The reduction in the absolute and relative number of B-lymphocytes suggested insufficiency of the B cell-dependent component of the immune system in the children that was especially well-pronounced in the younger age group.
authors.forename: N V
authors.initials: NV
authors.lastname: Terskova
authors.forename: N I
authors.initials: NI
authors.lastname: Kamzalakova
authors.forename: S G
authors.initials: SG
authors.lastname: Vakhrushev
authors.forename: A S
authors.initials: AS
authors.lastname: Smbatian
mesh_terms: D000234:Adenoids / Q000276:immunology* / Q000473:pathology; D001402:B-Lymphocytes / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D016130:Immunophenotyping / Q000379:methods; D007958:Leukocyte Count; D008213:Lymphocyte Activation / Q000276:immunology; D008297:Male; D012189:Retrospective Studies; D013601:T-Lymphocytes / Q000276:immunology*; D014069:Tonsillitis / Q000276:immunology* / Q000473:pathology