title: The new aryl hydrocarbon receptor antagonist E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one protects against UVB-induced signal transduction.
authors.affiliation: IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.
authors.forename: Julia
authors.initials: J
authors.lastname: Tigges
authors.affiliation: IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Haarmann-Stemmann
authors.affiliation: Department of Environmental Toxicology and Center for Health and the Environment, University of California, Davis, Davis, California, USA.
authors.forename: Christoph F A
authors.initials: CFA
authors.lastname: Vogel
authors.affiliation: Department of Environmental Toxicology and Center for Health and the Environment, University of California, Davis, Davis, California, USA.
authors.forename: Annemarie
authors.initials: A
authors.lastname: Grindel
authors.affiliation: IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.
authors.forename: Ulrike
authors.initials: U
authors.lastname: Hübenthal
authors.affiliation: IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.
authors.forename: Heidi
authors.initials: H
authors.lastname: Brenden
authors.affiliation: IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.
authors.forename: Susanne
authors.initials: S
authors.lastname: Grether-Beck
authors.affiliation: Symrise GmbH & Co. KG, Holzminden, Germany.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Vielhaber
authors.affiliation: Symrise GmbH & Co. KG, Holzminden, Germany.
authors.forename: William
authors.initials: W
authors.lastname: Johncock
authors.affiliation: IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany. Electronic address: jean.krutmann@IUF-duesseldorf.de.
authors.forename: Jean
authors.initials: J
authors.lastname: Krutmann
authors.affiliation: IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.
authors.forename: Ellen
authors.initials: E
authors.lastname: Fritsche
mesh_terms: D001597:Benzylidene Compounds / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D007189:Indans / Q000737:chemistry / Q000494:pharmacology*; D015603:Keratinocytes / Q000187:drug effects*; D018336:Receptors, Aryl Hydrocarbon / Q000037:antagonists & inhibitors* / Q000737:chemistry; D015398:Signal Transduction / Q000187:drug effects* / Q000528:radiation effects*; D013329:Structure-Activity Relationship; D014466:Ultraviolet Rays
chemical_list: C587262:2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one; D001597:Benzylidene Compounds; D007189:Indans; D018336:Receptors, Aryl Hydrocarbon