title: [Comparative antioxidant and antihypoxic activities of new 1,4-dihydro-4-oxopyrimidine derivative--compound PDMpT.HCl and mexidol].
abstract: Compound PDMpT.HCI reduces intensity of lipoperoxidation, activates antioxidant system and increases animal life expectancy under hypoxic circumstance.
authors.forename: E V
authors.initials: EV
authors.lastname: Petrova
authors.forename: É T
authors.initials: ÉT
authors.lastname: Oganesian
authors.forename: I P
authors.initials: IP
authors.lastname: Kodonidi
authors.forename: E N
authors.initials: EN
authors.lastname: Zhoglo
mesh_terms: D000818:Animals; D021461:Animals, Outbred Strains; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D006112:Gravitation; D020925:Hypoxia-Ischemia, Brain / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D015227:Lipid Peroxidation / Q000187:drug effects; D008136:Longevity / Q000187:drug effects; D008297:Male; D051379:Mice; D010847:Picolines / Q000494:pharmacology; D011743:Pyrimidines / Q000737:chemistry / Q000494:pharmacology*; D011744:Pyrimidinones / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D015427:Reperfusion Injury / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D013482:Superoxide Dismutase / Q000378:metabolism; D014050:Toluene / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology
chemical_list: C583667:2,6-dimethyl-5-phenyl-1-p-tolyl-1H-pyrimidin-4-one; D000975:Antioxidants; D010847:Picolines; D011743:Pyrimidines; D011744:Pyrimidinones; C070020:emoxypine succinate; D014050:Toluene; D013482:Superoxide Dismutase