title: [Comparative morphology of the gastric mucosa in asthmatic patients using inhaled glucocorticosteroid therapy].
abstract: The immunomorphological characteristics of the gastric mucosa were evaluated and analyzed in patients with asthma of varying severity who received or did not receive inhaled or oral glucocorticosteroid therapy and in the control group. Immunohistological examination and morphometric analysis were used to study inflammatory infiltration in fundic mucosal biopsy specimens from patients with and without asthma. There were crucial immunomorphological differences between the examined patient groups and signs of the gastroprotective effect of inhaled glucocorticosteroids used in the basic therapy of asthma on the gastric mucosa. There was evidence that it is urgent to prevent erosive and atrophic gastritis and other inflammatory stomach diseases in asthma.
authors.forename: L M
authors.initials: LM
authors.lastname: Mikhaleva
authors.forename: T G
authors.initials: TG
authors.lastname: Barkhina
authors.forename: N N
authors.initials: NN
authors.lastname: Shchegoleva
authors.forename: N A
authors.initials: NA
authors.lastname: Gracheva
authors.forename: V E
authors.initials: VE
authors.lastname: Golovanova
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D001249:Asthma / Q000188:drug therapy / Q000473:pathology; D005260:Female; D005748:Gastric Fundus / Q000473:pathology; D005753:Gastric Mucosa / Q000473:pathology*; D005757:Gastritis, Atrophic / Q000139:chemically induced* / Q000473:pathology*; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D005938:Glucocorticoids