title: [Current status and future perspectives of hepatocyte transplantation].
abstract: The imbalance between the number of potential beneficiaries and available organs, originates the search for new therapeutic alternatives, such as Hepatocyte transplantation (HT).Even though this is a treatment option for these patients, the lack of unanimity of criteria regarding indications and technique, different cryopreservation protocols, as well as the different methodology to assess the response to this therapy, highlights the need of a Consensus Conference to standardize criteria and consider future strategies to improve the technique and optimize the results.Our aim is to review and update the current state of hepatocyte transplantation, emphasizing the future research attempting to solve the problems and improve the results of this treatment.
authors.affiliation: Unidad de Cirugía Hepato-Bilio-Pancreática y Trasplante Hepático, Hospital Universitario La Fe de Valencia, Valencia, España; Unidad de Terapia Celular Hepática, Hospital Universitario La Fe de Valencia, Valencia, España. Electronic address: gomez_mjo@gva.es.
authors.forename: Eugenia
authors.initials: E
authors.lastname: Pareja
authors.affiliation: Unidad de Cirugía Hepato-Bilio-Pancreática y Trasplante Hepático, King's College Hospital, Institute of Liver Study, Londres, Reino Unido.
authors.forename: Miriam
authors.initials: M
authors.lastname: Cortés
authors.affiliation: Unidad de Terapia Celular Hepática, Hospital Universitario La Fe de Valencia, Valencia, España; Unidad de Hepatología Experimental, Centro de Investigación, Hospital Universitario La Fe de Valencia, Valencia, España.
authors.forename: M José
authors.initials: MJ
authors.lastname: Gómez-Lechón
authors.affiliation: Unidad de Cirugía Hepato-Bilio-Pancreática y Trasplante Hepático, Hospital Universitario La Fe de Valencia, Valencia, España.
authors.forename: Javier
authors.initials: J
authors.lastname: Maupoey
authors.affiliation: Unidad de Cirugía Hepato-Bilio-Pancreática y Trasplante Hepático, Hospital Universitario La Fe de Valencia, Valencia, España.
authors.forename: Fernando
authors.initials: F
authors.lastname: San Juan
authors.affiliation: Unidad de Cirugía Hepato-Bilio-Pancreática y Trasplante Hepático, Hospital Universitario La Fe de Valencia, Valencia, España.
authors.forename: Rafael
authors.initials: R
authors.lastname: López
authors.affiliation: Unidad de Cirugía Hepato-Bilio-Pancreática y Trasplante Hepático, Hospital Universitario La Fe de Valencia, Valencia, España; Unidad de Terapia Celular Hepática, Hospital Universitario La Fe de Valencia, Valencia, España.
authors.forename: Jose
authors.initials: J
authors.lastname: Mir
mesh_terms: D017690:Cell Transplantation / Q000379:methods* / Q000639:trends*; D005544:Forecasting; D022781:Hepatocytes / Q000637:transplantation*; D006801:Humans; D008107:Liver Diseases / Q000601:surgery*
keywords: Criopreservación; Cryopreservation; Células madre pluripotentes inducidas.; Células madre progenitoras; Errores congénitos del metabolismo; Hepatic cell transplantation; Inborn errors of metabolism; Induced pluripotent stem cells; Liver transplantation; Preacondicionamiento hepático; Preconditioning liver; Progenitor stem cell; Trasplante celular hepático; Trasplante hepático