title: [Relationship between maternal milk and serum thyroid hormones in patients with thyroid related diseases].
abstract: OBJECTIVE
  To explore the relationship between maternal milk and serum thyroid hormones in patients with thyroid-related diseases.
  
  
  METHODS
  Serum and breast milk samples were collected from 56 breastfeeding mothers. Milk and serum free triiodothyronine (FT3), free thyroxine (FT4), triiodothyronine(T3), thyroxine (T4), and thyrotrophin (TSH) were determined, and T3/T4 was calculated. Using the serum thyroid hormones as the independent variables and milk thyroid hormones as the dependent variables, we performed linear regression analysis.
  
  
  RESULTS
  The milk FT3, FT4, T3, T4, TSH, and T3/T4 were (2.30 ± 0.82) pg/ml ,(0.45 ± 0.26) ng/dl, (0.35 ± 0.20) ng/ml, (2.96 ± 1.55) Μg/dl, (0.12 ± 0.08) ΜU/ml, and 0.12 ± 0.04, respectively. Milk FT3 (r = 0.778, P = 0.000), T3 (r = 0.603, P = 0.000), T4 (r = 0.485, P = 0.004), and TSH (r = 0.605, P = 0.000) concentrations were positively correlated with those in serum.
  
  
  CONCLUSIONS
  Thyroid hormones are present in human milk and are positively correlated with those in serum.
authors.affiliation: Department of Endocrinology, PUMC Hospital, Beijing, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhang
authors.forename: Xiao-lan
authors.initials: XL
authors.lastname: Lian
authors.forename: Xiao-feng
authors.initials: XF
authors.lastname: Chai
authors.forename: Yao
authors.initials: Y
authors.lastname: Bai
authors.forename: Wei-xin
authors.initials: WX
authors.lastname: Dai
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008895:Milk, Human / Q000737:chemistry*; D013959:Thyroid Diseases / Q000097:blood*; D013963:Thyroid Hormones / Q000097:blood* / Q000737:chemistry; D013972:Thyrotropin / Q000097:blood / Q000737:chemistry; D014284:Triiodothyronine / Q000097:blood / Q000737:chemistry
chemical_list: D013963:Thyroid Hormones; D014284:Triiodothyronine; D013972:Thyrotropin