title: Sleep duration and glycemic control in patients with diabetes mellitus: Korea National Health and Nutrition Examination Survey 2007-2010.
abstract: Short sleep duration has been reported to increase the risk of diabetes. However, the influence of sleep duration on glycemic control in diabetic patients has not been clarified. In this study we evaluated the association between sleep duration and glycemic control in diabetic patients. We analyzed the data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2007-2010. Sleep duration was classified into five groups: <6, 6, 7, 8, and ≥9 h/day. Fasting blood glucose and HbA1c showed a U-shaped trend according to sleep duration. Sleep duration of 7 h/day had the lowest HbA1c (7.26%) among the subjects (P=0.026). In the older age group (≥65 yr), a sleep duration of 6 h/day was associated with the lowest HbA1c (7.26%). The adjusted odds ratio (OR) with a 95% confidence interval (CI) of worse glycemic control (HbA1c ≥7.0%) in group of sleep duration of ≥9 h/day was 1.48 (1.04-2.13) compared with the group of 7 h/day. This relationship disappeared after adjusting duration of diabetes (OR, 1.38; 95% CI, 0.93-2.03). Our results suggest that sleep duration and glycemic control in diabetic patients has U-shaped relationship which was mainly affected by duration of diabetes.
authors.affiliation: Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.
authors.forename: Bu Kyung
authors.initials: BK
authors.lastname: Kim
authors.forename: Bong Sun
authors.initials: BS
authors.lastname: Kim
authors.forename: So-Yeon
authors.initials: SY
authors.lastname: An
authors.forename: Min Suk
authors.initials: MS
authors.lastname: Lee
authors.forename: Yong Jun
authors.initials: YJ
authors.lastname: Choi
authors.forename: Seung Jin
authors.initials: SJ
authors.lastname: Han
authors.forename: Yoon-sok
authors.initials: YS
authors.lastname: Chung
authors.forename: Kwan-Woo
authors.initials: KW
authors.lastname: Lee
authors.forename: Dae Jung
authors.initials: DJ
authors.lastname: Kim
mesh_terms: D000367:Age Factors; D000368:Aged; D044466:Asian People; D001786:Blood Glucose / Q000032:analysis*; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis* / Q000378:metabolism; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D016017:Odds Ratio; D056910:Republic of Korea; D012307:Risk Factors; D012890:Sleep / Q000502:physiology*
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin
keywords: Diabetes Mellitus; Insulin Resistance; Sleep