title: [Evaluation of the efficacy of a Soybean Allergenic Extract in the Diagnosis of Immediate Hypersensitivity].
abstract: BACKGROUND
  Allergy to soybean has an increasing tendency due to the high consumption of soybean as a basic food resource available in poor countries, and also for being so widely used for commercial purposes. This fact demands the development of safer and cheaper allergenic extracts for skin prick tests, with better diagnostic accuracy.
  
  
  OBJECTIVE
  To evaluate the safety and diagnostic accuracy of a soybean¥s extract for skin prick test to diagnose food allergy.
  
  
  METHODS
  In this observational and prospective research 60 individuals were studied, 30 of them with the clinical diagnosis of soybean¥s allergy and 30 controls. Skin prick tests were performed with both, shell and soybean grain extracts (0,1mg/mL and 1mg/mL), and specificity, sensitivity and accuracy were calculated.
  
  
  RESULTS
  Sixty percent of all patients with soybean allergy showed a positive result to soybean grain extract. On the other hand, the patients in the control group had all negative results for both allergen extract concentrations (p < 0.05). All extracts¥ dilutions have 100% specificity. We observed that the soybean grain extract at 1 mg/mL was sensitive in 60%, specific in 100% and effective in 80% for soybean allergy diagnosis.
  
  
  CONCLUSIONS
  The soybean grain extract has both safety and diagnostic accuracy for the diagnosis of food allergy to soybean at the higher concentration.
authors.affiliation: Servicio de AlergologÌa, Hospital CQ Hermanos Ameijeiras, La Habana, Cuba. iglermis@infomed.sld.cu.
authors.forename: Iglermys
authors.initials: I
authors.lastname: Figueroa-Garcìa
authors.forename: Ilonka María
authors.initials: IM
authors.lastname: Estruch-Fajardo
authors.forename: Alexis
authors.initials: A
authors.lastname: Labrada-Rosado
authors.forename: Marilys
authors.initials: M
authors.lastname: León-Rivero
mesh_terms: D000485:Allergens; D005512:Food Hypersensitivity / Q000175:diagnosis; D006801:Humans; D006969:Hypersensitivity, Immediate; D011446:Prospective Studies; D012882:Skin Tests; D013025:Glycine max
chemical_list: D000485:Allergens