title: Prognostic value of the qualitative assessments of general movements in late-preterm infants.
abstract: BACKGROUND
  The quality of general movements (GMs) and its predictive value have never been evaluated in late-preterm (LP) infants.
  
  
  OBJECTIVE
  To determine the characteristics of GMs and their predictive value for neurodevelopmental outcome in a cohort of infants born between 34 and 36 weeks' gestation.
  
  
  METHODS
  574 LP infants were examined using the standard methodological principles of Prechtl's method for assessing GMs both during writhing and fidgety periods.
  
  
  METHODS
  Infants were assessed at 2 years of age with neuromotor and developmental scales.
  
  
  RESULTS
  A significant correlation was found between GMs and outcome both at writhing (rs 0.68; p < 0.001) and at fidgety age (rs 0.78; p < 0.001). The assessment at 1 month showed 100% sensitivity and 86% specificity of predicting the development of cerebral palsy (CP), that at 3 months was 100% sensitivity and 97% specificity.
  
  
  CONCLUSIONS
  During the fidgety age GMs predict CP with very high sensitivity and specificity. The qualitative assessment of GMs should be employed to help identify LP infants who require early intervention for neurological abnormalities.
authors.affiliation: Paediatric Neurology Unit, Catholic University, Rome, Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Brogna
authors.forename: Domenico M
authors.initials: DM
authors.lastname: Romeo
authors.forename: Chiara
authors.initials: C
authors.lastname: Cervesi
authors.forename: Luana
authors.initials: L
authors.lastname: Scrofani
authors.forename: Mario G
authors.initials: MG
authors.lastname: Romeo
authors.forename: Eugenio
authors.initials: E
authors.lastname: Mercuri
authors.forename: Andrea
authors.initials: A
authors.lastname: Guzzetta
mesh_terms: D000367:Age Factors; D002547:Cerebral Palsy / Q000175:diagnosis*; D002657:Child Development / Q000502:physiology*; D002675:Child, Preschool; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000502:physiology*; D007558:Italy; D009068:Movement / Q000502:physiology*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
keywords: Cerebral palsy; General movements; Late preterm; Neurological outcome