title: Subdural haematoma in Plasmodium falciparum and Plasmodium vivax mixed infection presenting multiple clinical complications.
abstract: A 40-year-old man was admitted to hospital with a 5 day history of fever, restlessness and altered sensorium. Peripheral blood smears showed a Plasmodium vivax and Plasmodium falciparum mixed infection as revealed by the presence of rings, schizonts and gametocyte forms of the parasites. The patient soon became unconscious due to subdural haematoma (SDH) associated with disseminated intravascular coagulation and thrombocytopenia. Immediate intervention with a right fronto-parieto temporal craniectomy, evacuation of the SDH and intravenous quinine administration resulted in the patient's complete recovery within 8 days of admission, and he was discharged in good clinical condition.
authors.affiliation: Department of Biochemistry, Kuvempu University, Shankaraghatta-577451, Shimoga, India.
authors.forename: Punith B
authors.initials: PB
authors.lastname: Devaraju
authors.affiliation: Department of Biochemistry, Kuvempu University, Shankaraghatta-577451, Shimoga, India.
authors.forename: Shashiraja
authors.initials: S
authors.lastname: Padukone
authors.affiliation: Department of Biochemistry, Kuvempu University, Shankaraghatta-577451, Shimoga, India.
authors.forename: Shivakumar R
authors.initials: SR
authors.lastname: Veerabhadraiah
authors.affiliation: Department of Biochemistry, Kuvempu University, Shankaraghatta-577451, Shimoga, India.
authors.forename: Vijayakumar S
authors.initials: VS
authors.lastname: Ramachandrappa
authors.affiliation: Department of Neurology, Nanjappa Hospital, Kuvempu Road, Shimoga-577201, India.
authors.forename: Narayan
authors.initials: N
authors.lastname: Panji
authors.affiliation: Department of Medicine, Vaatsalya Hospital, Park Extension, Shimoga-577201, India.
authors.forename: Pruthvi B
authors.initials: PB
authors.lastname: Chandrappagowda
authors.affiliation: Department of Internal Medicine, Shivamogga Institute of Medical Sciences, Shimoga-577201, India.
authors.forename: Maheshmurthy B
authors.initials: MB
authors.lastname: Rudrappa
authors.affiliation: Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
authors.forename: D Channe
authors.initials: DC
authors.lastname: Gowda
authors.affiliation: Department of Biochemistry, Kuvempu University, Shankaraghatta-577451, Shimoga, India.
authors.forename: Rajeshwara N
authors.initials: RN
authors.lastname: Achur
mesh_terms: D000328:Adult; D060085:Coinfection / Q000175:diagnosis* / Q000178:diet therapy; D006801:Humans; D016778:Malaria, Falciparum / Q000175:diagnosis* / Q000178:diet therapy; D016780:Malaria, Vivax / Q000175:diagnosis* / Q000178:diet therapy; D008297:Male; D010963:Plasmodium falciparum / Q000302:isolation & purification*; D010966:Plasmodium vivax / Q000302:isolation & purification*; D011803:Quinine / Q000627:therapeutic use
chemical_list: D011803:Quinine