title: Multimodality imaging features of hereditary multiple exostoses.
abstract: Hereditary multiple exostoses (HME) or diaphyseal aclasis is an inherited disorder characterised by the formation of multiple osteochondromas, which are cartilage-capped osseous outgrowths, and the development of associated osseous deformities. Individuals with HME may be asymptomatic or develop clinical symptoms, which prompt imaging studies. Different modalities ranging from plain radiographs to cross-sectional and nuclear medicine imaging studies can be helpful in the diagnosis and detection of complications in HME, including chondrosarcomatous transformation. We review the role and imaging features of these different modalities in HME.
authors.affiliation: Department of Radiology, Tallaght Hospital, Dublin, Ireland. terrykok@gmail.com
authors.forename: H K
authors.initials: HK
authors.lastname: Kok
authors.forename: L
authors.initials: L
authors.lastname: Fitzgerald
authors.forename: N
authors.initials: N
authors.lastname: Campbell
authors.forename: I D
authors.initials: ID
authors.lastname: Lyburn
authors.forename: P L
authors.initials: PL
authors.lastname: Munk
authors.forename: O
authors.initials: O
authors.lastname: Buckley
authors.forename: W C
authors.initials: WC
authors.lastname: Torreggiani
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000150:complications; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000473:pathology; D002471:Cell Transformation, Neoplastic; D002813:Chondrosarcoma / Q000150:complications; D003952:Diagnostic Imaging; D005097:Exostoses, Multiple Hereditary / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008297:Male; D011859:Radiography; D011877:Radionuclide Imaging