title: [Good glycaemic control can prevent diabetic peripheral neuropathy].
abstract: Diabetic peripheral neuropathy (DPN) results in excess morbidity and mortality. Good glycaemic control is the only way to reduce the risk of DPN. A Cochrane review meta-analysed RCTs on the impact of improved glycaemic control on peripheral neuropathy (primary outcome). The few studies addressing the primary outcome showed that improving glycaemic control reduces clinical neuropathy in type 1 diabetes whereas the evidence is less for type 2 diabetes. Several secondary outcomes (e.g. motor nerve conduction) are also improved. Prevention of DPN is a delicate balance between good glycaemic control and reducing the risk of severe hypoglycaemia.
authors.affiliation: Medicinsk Endokrinologisk Afdeling MEA, Aarhus Universitetshospital, Tage-Hansens Gade 2, Aarhus C. soeren.gregersen@aarhus.rm.dk
authors.forename: Søren
authors.initials: S
authors.lastname: Gregersen
mesh_terms: D001786:Blood Glucose / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications; D003929:Diabetic Neuropathies / Q000097:blood / Q000517:prevention & control; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000517:prevention & control; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*; D012196:Review Literature as Topic
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin