title: Negative-pressure wound therapy with instillation: international consensus guidelines.
abstract: BACKGROUND
  Negative-pressure wound therapy with instillation is increasingly utilized as an adjunct therapy for a wide variety of wounds. Despite its growing popularity, there is a paucity of evidence and lack of guidance to provide effective use of this therapy.
  
  
  METHODS
  A panel of experts was convened to provide guidance regarding the appropriate use of negative-pressure wound therapy with instillation. A face-to-face meeting was held where the available evidence was discussed and individual clinical experience with this therapy was shared. Follow-up communication among the panelists continued until consensus was achieved. The final consensus recommendations were derived through more than 80 percent agreement among the panelists.
  
  
  RESULTS
  Nine consensus statements were generated that address the appropriate use of negative-pressure wound therapy with instillation. The question of clinical effectiveness of this therapy was not directly addressed by the consensus panel.
  
  
  CONCLUSIONS
  This document serves as preliminary guidelines until more robust evidence emerges that will support or modify these consensus recommendations.
authors.affiliation: Washington, D.C.; Heidelberg and Berlin, Germany; Dallas, Texas; Scottsdale, Ariz.; Boston, Mass.; Chicago, Ill.; New York, N.Y.; Vancouver, Wash.; Gainesville, Fla. From the Department of Plastic Surgery, Georgetown University Hospital; the Orthopedic and Trauma Clinic, Heidelberg University; Department of Trauma Senior Surgery and Orthopedics, Reconstructive, Septic, and Hand Surgery, Military Hospital Berlin; the Department of Plastic Surgery, University of Texas Southwestern; the Division of General Surgery, Scottsdale Healthcare Osborn Medical Center; the Department of Surgery, Harvard Medical School; the Department of Clinical Surgery, University of Illinois at Chicago; the Department of Surgery, Columbia University; the Department of Plastic and Maxillofacial Surgery, Southwest Washington Medical Center; and the Department of Wound Research, University of Florida.
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Kim
authors.forename: Christopher E
authors.initials: CE
authors.lastname: Attinger
authors.forename: John S
authors.initials: JS
authors.lastname: Steinberg
authors.forename: Karen K
authors.initials: KK
authors.lastname: Evans
authors.forename: Burkhard
authors.initials: B
authors.lastname: Lehner
authors.forename: Christian
authors.initials: C
authors.lastname: Willy
authors.forename: Larry
authors.initials: L
authors.lastname: Lavery
authors.forename: Tom
authors.initials: T
authors.lastname: Wolvos
authors.forename: Dennis
authors.initials: D
authors.lastname: Orgill
authors.forename: William
authors.initials: W
authors.lastname: Ennis
authors.forename: John
authors.initials: J
authors.lastname: Lantis
authors.forename: Allen
authors.initials: A
authors.lastname: Gabriel
authors.forename: Gregory
authors.initials: G
authors.lastname: Schultz
mesh_terms: D032921:Consensus; D019317:Evidence-Based Medicine; D006801:Humans; D054843:Negative-Pressure Wound Therapy / Q000379:methods* / Q000592:standards*; D017410:Practice Guidelines as Topic; D014945:Wound Healing; D014947:Wounds and Injuries / Q000628:therapy*