title: A case report of human immunodeficiency virus-associated anaplastic lymphoma kinase protein-negative anaplastic large cell lymphoma.
abstract: Human immunodeficiency virus (HIV)-associated anaplastic large cell lymphoma (ALCL) is not so common, and anaplastic lymphoma kinase protein (ALK)-negative ALCL is rare and has a low survival rate. We report a case of a 31-year-old Japanese man diagnosed with HIV-associated ALK-negative ALCL who presented with long-lasting fever of unknown origin. The diagnosis was based on a full work-up that included inguinal lymph-node biopsy. Eight-cycle chemotherapy that included cyclophosphamide, doxorubicin, vincristine, and prednisone in addition to antiretroviral therapy for HIV infection provided a complete remission of his ALCL and over 5-year survival for him.
authors.affiliation: Department of General Internal Medicine, Kyushu University Hospital, 3-1-1, Maidashi, Higashi-Ku, Fukuoka, 812-8582 Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Taniai
authors.forename: Norihiro
authors.initials: N
authors.lastname: Furusyo
authors.forename: Masayuki
authors.initials: M
authors.lastname: Murata
authors.forename: Fujiko
authors.initials: F
authors.lastname: Mitsumoto
authors.forename: Motohiro
authors.initials: M
authors.lastname: Shimizu
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Toyoda
authors.forename: Eiichi
authors.initials: E
authors.lastname: Ogawa
authors.forename: Mosaburo
authors.initials: M
authors.lastname: Kainuma
authors.forename: Kyoko
authors.initials: K
authors.lastname: Okada
authors.forename: Jun
authors.initials: J
authors.lastname: Hayashi
keywords: Anaplastic large cell lymphoma; Anaplastic lymphoma kinase; Human immunodeficiency virus