title: Stability of cefepime hydrochloride dextrose in 5% dextrose injection and 0.9% sodium chloride injection.
abstract: The stability of cefepime hydrochloride in 5% dextrose injection and 0.9% sodium chloride injection was studied using a stability-indicating assay method developed in our laboratory. This method is precise and accurate, with a percent relative standard deviation of 0.7% based on five readings. The admixtures were stable for two days at 25 deg C and 23 days at 5 deg C. The pH values of the admixtures did not change throughout this study, and the colors had changed from a very light yellow to a light yellow. The manufacturer recommends an expiry date of 24 hours at 20 to 25 deg C and seven days at 2 to 8 deg C.
authors.affiliation: Division of Pharmaceutics, University of Houston, Houston, TX.
authors.forename: V D
authors.initials: VD
authors.lastname: Gupta
authors.forename: J
authors.initials: J
authors.lastname: Maswoswe
authors.forename: R E
authors.initials: RE
authors.lastname: Bailey