title: The effect of age on Br, Ca, Cl, K, Mg, Mn, and Na mass fraction in pediatric and young adult prostate glands investigated by neutron activation analysis.
abstract: The effect of age on chemical element mass fractions in intact prostate of 50 apparently healthy 0-30 year old males was investigated by neutron activation analysis with high resolution spectrometry of short-lived radionuclides. Mean values (M ± SΕΜ) for mass fraction (mgkg(-1), dry mass basis) of chemical elements before the time of puberty and in the period of puberty and post-puberty were: Br 46.0 ± 6.7, Ca 1151 ± 140, Cl 14572 ± 700, K 10147 ± 700, Mg 771 ± 131, Mn 2.13 ± 0.25, Na 9880 ± 659 and Br 29.0 ± 4.6, Ca 2049 ± 364, Cl 11518 ± 1121, K 13029 ± 542, Mg 1186 ± 134, Mn 1.74 ± 0.16, Na 9887 ± 716, respectively. A tendency of age-related increase in Ca, K, and Mg mass fraction and of age-related decrease in Br mass fraction was observed in period of life from 0 to 30 years. This new data indicates that of the elements studied, only the Ca, K, and Mg mass fraction in prostate tissue is an androgen-dependent parameter.
authors.affiliation: Radionuclide Diagnostics Department, Medical Radiological Research Centre, Koroleva Str.-4, Obninsk 249036, Kaluga Region, Russia. Electronic address: vezai@obninsk.com.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Zaichick
authors.forename: Sofia
authors.initials: S
authors.lastname: Zaichick
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001774:Blood Chemical Analysis; D001966:Bromine / Q000032:analysis; D002118:Calcium / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D002713:Chlorine / Q000032:analysis; D004602:Elements; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008099:Liver / Q000737:chemistry; D008297:Male; D008345:Manganese / Q000032:analysis; D009501:Neutron Activation Analysis; D011188:Potassium / Q000032:analysis; D011467:Prostate / Q000737:chemistry*; D011627:Puberty / Q000378:metabolism; D012016:Reference Values; D012964:Sodium / Q000032:analysis; D055815:Young Adult
chemical_list: D004602:Elements; D008345:Manganese; D002713:Chlorine; D012964:Sodium; D011188:Potassium; D001966:Bromine; D002118:Calcium
keywords: Neutron activation analysis; Pediatric and young adult prostate glands; Trace elements