title: [Etiology of fatal pneumonia caused by influenza A(H1N1)pdm2009 virus during the pandemic in Russia].
abstract: The results of the study of the autopsy materials from 61 patients with the diagnosis of pneumonia received by virological and genetic methods are reviewed. The materials were studied at the Influenza Etiology and Epidemiology Center of the Ivanovsky Institute of Virology, Ministry of Health and Social Development of the Russian Federation, during epidemic seasons 2009-2010 and 2010-2011. The data were analyzed with respect to age, sex, comorbidity diseases and identified on the groups of the risk of severe forms of the disease. The presence of the pandemic influenza virus strain RNA was confirmed in 70.5% of materials; RNA of influenza B was detected in 1.2% cases. The co-infections caused by the bocavirus, adenovirus, parainfluenza virus type 2 and 4, rhinovirus, and streptococcus were detected only in 19.7%. In most cases, the influenza virus was the etiologic agent of lethal pneumonia, which justifies the necessity of the early etiological diagnosis and treatment with antiviral drugs.
authors.forename: V V
authors.initials: VV
authors.lastname: Lavrishcheva
authors.forename: E I
authors.initials: EI
authors.lastname: Burtseva
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Khomiakov
authors.forename: E C
authors.initials: EC
authors.lastname: Shevchenko
authors.forename: T A
authors.initials: TA
authors.lastname: Oskerko
authors.forename: S M
authors.initials: SM
authors.lastname: Ivanova
authors.forename: M M
authors.initials: MM
authors.lastname: Danilevskaia
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Shchelkanov
authors.forename: I T
authors.initials: IT
authors.lastname: Fediakina
authors.forename: S V
authors.initials: SV
authors.lastname: Alkhovskiĭ
authors.forename: A G
authors.initials: AG
authors.lastname: Prilipov
authors.forename: M V
authors.initials: MV
authors.lastname: Zhuravleva
authors.forename: L V
authors.initials: LV
authors.lastname: Kolobukhina
authors.forename: N A
authors.initials: NA
authors.lastname: Malyshev
authors.forename: D K
authors.initials: DK
authors.lastname: L'vov
mesh_terms: D000257:Adenoviridae Infections / Q000453:epidemiology / Q000401:mortality / Q000821:virology; D000293:Adolescent; D000328:Adult; D000368:Aged; D001344:Autopsy; D002648:Child; D002675:Child, Preschool; D060085:Coinfection; D005260:Female; D006801:Humans; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D007251:Influenza, Human / Q000150:complications* / Q000453:epidemiology / Q000401:mortality / Q000821:virology; D008297:Male; D008875:Middle Aged; D058873:Pandemics; D010850:Picornaviridae Infections / Q000453:epidemiology / Q000401:mortality / Q000821:virology; D011024:Pneumonia, Viral / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality / Q000821:virology; D012367:RNA, Viral / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D012426:Russia / Q000453:epidemiology; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology / Q000401:mortality
chemical_list: D012367:RNA, Viral