title: The oxygen supply-demand balance: a monitoring challenge.
abstract: The principal task of acute critical care is to avoid or correct oxygen debt by increasing oxygen delivery (DO2) and/or decreasing oxygen consumption (VO2). The most commonly used methods to assess the relationship of adequate delivery and consumption are mixed venous oxygen saturation and its surrogate, central venous oxygen saturation (ScvO2). The purpose of this article is to review the values and limitations of the two parameters and evaluate the clinical use of ScvO2 in certain clinical scenarios, such as anaemia and transfusion, hypovolaemia, major surgery, septic shock, and in difficult-to-wean patients.
authors.affiliation: Department of Anaesthesia and Intensive Therapy, University of Szeged, 6, Semmelweis St, 6725 Szeged, Hungary. tkrisztian78@gmail.com
authors.forename: Krisztián
authors.initials: K
authors.lastname: Tánczos
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Molnár
mesh_terms: D000740:Anemia / Q000378:metabolism / Q000628:therapy; D000818:Animals; D001803:Blood Transfusion / Q000379:methods; D003422:Critical Care / Q000379:methods; D006801:Humans; D020896:Hypovolemia / Q000378:metabolism / Q000628:therapy; D008991:Monitoring, Physiologic / Q000379:methods*; D010100:Oxygen / Q000097:blood*; D010101:Oxygen Consumption / Q000502:physiology*; D012772:Shock, Septic / Q000378:metabolism / Q000628:therapy
chemical_list: D010100:Oxygen
keywords: central venous oxygen saturation; mixed venous oxygen saturation; oxygen consumption; oxygen delivery