title: Usefulness of ultrasonography in assessment of laryngeal carcinoma.
abstract: OBJECTIVE
  To evaluate the usefulness of ultrasonography in assessing laryngeal cancer.
  
  
  METHODS
  72 patients with laryngeal carcinoma proven by surgery and pathology were enrolled. The pre-therapeutic ultrasonography and CT images were retrospectively evaluated, including tumour detection, localisation and invasion of intra- and extralaryngeal structures. A comparative assessment was made between the detection rate, correspondence rate of localisation and sensitivity and specificity of ultrasonography and CT. The mobility of the larynx was observed on real-time ultrasonography and compared with laryngoscopy.
  
  
  RESULTS
  The detection rate of ultrasonography [63 (87.5%)/72] was lower than that of CT [72 (100.0%)/72] (p=0.006). The primary foci were accurately located in 59 (93.7%) of 63 lesions using ultrasonography compared with 70 (97.2%) of 72 lesions using CT (p=0.392). In the evaluation of invasion, the sensitivity and specificity of ultrasonography were similar to that of CT in most of the intra- and extralaryngeal structures (p=0.059-1.000). A higher specificity was obtained during the assessment of the paraglottic space involvement when using ultrasonography than CT (94.9% vs 66.7%, p=0.001). For vocal cord fixation, no statistical difference was found between ultrasonography and laryngoscopy (p=0.223).
  
  
  CONCLUSIONS
  Ultrasonography could be used as a valuable supplementary imaging method to CT and laryngoscopy in the assessment of laryngeal carcinoma, even in male adults with some calcifications of the thyroid cartilage.
  
  
  CONCLUSIONS
  Our study demonstrates that ultrasonography, which has been used scarcely in the larynx, could supply useful information on the detection, localisation and intra- and extralaryngeal invasion of laryngeal carcinoma.
authors.affiliation: Department of Diagnostic Ultrasound, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: C-X
authors.initials: CX
authors.lastname: Xia
authors.forename: Q
authors.initials: Q
authors.lastname: Zhu
authors.forename: H-X
authors.initials: HX
authors.lastname: Zhao
authors.forename: F
authors.initials: F
authors.lastname: Yan
authors.forename: S-L
authors.initials: SL
authors.lastname: Li
authors.forename: S-M
authors.initials: SM
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D007828:Laryngoscopy; D007830:Larynx / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013957:Thyroid Cartilage / Q000000981:diagnostic imaging / Q000473:pathology; D036542:Tomography, Spiral Computed; D014463:Ultrasonography; D014827:Vocal Cords / Q000000981:diagnostic imaging / Q000473:pathology