title: The peculiarities of food allergies in accordance with the level of injury of respiratory tract in children of Eastern Siberia.
abstract: OBJECTIVE
  To determine the course of food allergy in accordance with the level of respiratory tract injury in children of Eastern Siberia.
  We have examined 70 children aged 2-16 , who have food sensibilization. We divided them into 2 groups: group I (n = 32) with diseases of the upper and middle respiratory tract; and group II (n = 38) with diseases of the lower respiratory tract.
  
  
  METHODS
  Allergological medical history, clinical laboratory examination and immunological examination, including the determination of IgA, IgM, IgG and IgE in blood serum. In cases where causal allergens were found, elimination diets were recommended.
  
  
  RESULTS
  Onset of upper respiratory tract injury in group I was more often registered in children aged 0-1; in group II, it was in the 3-7 age group. Isolated food sensibilization was more often marked in group I as compared to group II. Atopic mechanisms of respiratory tract injuries were more often registered in group II children. In the course of the elimination diet, we marked positive dynamics in 100% of group I and in 75% of group II.
  
  
  CONCLUSIONS
  The most frequent allergens that cause respiratory forms of food allergy are hen eggs, cow milk, nutritive cereals, vegetables and fruit. Indices of a humoral link of immunity in the examined patients were more often registered as normal or their level is increased. Timely etiotropic therapy in the majority of cases allows for a stabilization of allergic inflammation.
authors.affiliation: Federal State Budget Institution, Scientific Research Institute for Medical Problems of the North, Siberian Division of Russian Academy of Medical Sciences, Krasnoyarsk, Russia. svetvita@mail.ru
authors.forename: Irina V
authors.initials: IV
authors.lastname: Borisova
authors.forename: Svetlana V
authors.initials: SV
authors.lastname: Smirnova
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000485:Allergens / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005502:Food; D005512:Food Hypersensitivity / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D056724:Immunity, Humoral / Q000276:immunology; D007070:Immunoglobulin A / Q000097:blood; D007073:Immunoglobulin E / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D012140:Respiratory Tract Diseases / Q000453:epidemiology* / Q000276:immunology; D012800:Siberia / Q000453:epidemiology
chemical_list: D000485:Allergens; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007073:Immunoglobulin E
keywords: elimination diet; food allergy; respiratory tract