title: [Advancement in the research of early detection of bacterial nucleic acid in molecular diagnosis of sepsis].
abstract: Early diagnosis of sepsis helps make effective clinical decisions and improve the survival rate of patients with severe infection. However, the timely and accurate diagnosis of sepsis is still a great challenge in clinic. In order to settle the very problem, the scientists in the world have made a lot of exploration and research in the field of rapid molecular identification of pathogens. Nowadays, the nucleic acid detection of sepsis is mainly composed of 3 types of methodological strategies, either based on positive blood culture, single colonies, or directly on blood specimens. This paper presents a comprehensive overview of advances in the research of early detection of bacterial nucleic acid as molecular diagnosis of sepsis.
authors.affiliation: School of Nursing, the Third Military Medical University, Chongqing 400038, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Liu
authors.forename: Hui
authors.initials: H
authors.lastname: Ren
authors.forename: Dai-zhi
authors.initials: DZ
authors.lastname: Peng
mesh_terms: D004269:DNA, Bacterial / Q000097:blood*; D006801:Humans; D018805:Sepsis / Q000097:blood / Q000175:diagnosis*
chemical_list: D004269:DNA, Bacterial