title: [Antibodies to neurotransmitters as possible neuroimmune risk markers of formation dependence to psychoactive substances].
abstract: In the sera of patients with opioid addiction has been found elevated levels of autoantibodies to the neurotransmitters dopamine, norepinephrine and serotonin in comparison with a control group of healthy people of the same age. In the group of patients with acute withdrawal was showed a reduction of antibody to dopamine, noradrenaline and serotonin in the blood serum when compared with patients in the period of postabstinent disorders. In the group of patients with risk for the formation of substance dependence in serum was observed decrease in autoantibodies to dopamine and norepinephrine compared with the control group.
authors.affiliation: Institute for General Pathology and Pathophysiology, RAMS, Mosow, Russia
authors.forename: T V
authors.initials: TV
authors.lastname: Davydova
authors.forename: L A
authors.initials: LA
authors.lastname: Vetrile
authors.forename: T P
authors.initials: TP
authors.lastname: Vetlugina
authors.forename: T I
authors.initials: TI
authors.lastname: Nevidimova
authors.forename: N A
authors.initials: NA
authors.lastname: Bokhan
authors.forename: E I
authors.initials: EI
authors.lastname: Batukhtina
authors.forename: V G
authors.initials: VG
authors.lastname: Fomina
authors.forename: I A
authors.initials: IA
authors.lastname: Zakharova
mesh_terms: D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D018377:Neurotransmitter Agents / Q000276:immunology*; D013375:Substance Withdrawal Syndrome / Q000097:blood / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D015415:Biomarkers; D018377:Neurotransmitter Agents