title: Cobalt-catalyzed oxidative [3 + 2] cycloaddition reactions: an efficient synthesis of pyrrolo- and imidazo-[2,1-a]isoquinolines.
abstract: A cobalt-catalyzed oxidative [3 + 2] cycloaddition cascades of dihydroisoquinoline esters with nitroolefins or N-sulfuryl aldimines were developed at room temperature. A multi-component reaction for the synthesis of 5,6-dihydroimidazo[2,1-a]isoquinolines were also realized under almost identical conditions. This method is particularly suitable for the synthesis of tricyclic nitrogen heterocycles due to its simple manipulation, wide scope of the reaction substrates and excellent regioselectivity.
authors.affiliation: Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China. zwang3@ustc.edu.cn.
authors.forename: Chengtao
authors.initials: C
authors.lastname: Feng
authors.forename: Ji-Hu
authors.initials: JH
authors.lastname: Su
authors.forename: Yizhe
authors.initials: Y
authors.lastname: Yan
authors.forename: Fengfeng
authors.initials: F
authors.lastname: Guo
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Wang