title: Hemicortical resection and reconstruction using pasteurised autograft for parosteal osteosarcoma of the distal femur.
abstract: The aim of this study was to assess a specific protocol for the treatment of patients with a parosteal osteosarcoma of the distal femur with limb salvage involving hemicortical resection and reconstruction using recycled pasteurised autograft and internal fixation. Between January 2000 and January 2010, 13 patients with a mean age of 26.5 years (17 to 39) underwent this procedure. All the tumours were staged according to Enneking's criteria: there were eight stage IA tumours and five stage IB tumours. The mean follow-up was 101.6 months (58 to 142), and mean post-operative Musculoskeletal Tumour Society functional score was 88.6% (80% to 100%) at the final follow-up. All the patients had achieved bony union; the mean time to union was 11.2 months (6 to 18). Local recurrence occurred in one patient 27 months post-operatively. No patient had a pulmonary metastasis. A hemicortical procedure for the treatment of a parosteal osteosarcoma is safe and effective. Precise pre-operative planning using MRI is essential in order to define the margins of resection. Although it is a technically demanding procedure, gratifying results make it worthwhile for selected patients.
authors.affiliation: Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
authors.forename: T
authors.initials: T
authors.lastname: Liu
authors.forename: Z-Y
authors.initials: ZY
authors.lastname: Liu
authors.forename: Q
authors.initials: Q
authors.lastname: Zhang
authors.forename: X-S
authors.initials: XS
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D016025:Bone Transplantation / Q000379:methods*; D005260:Female; D005266:Femoral Neoplasms / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012516:Osteosarcoma / Q000601:surgery*; D061352:Pasteurization / Q000379:methods; D016879:Salvage Therapy / Q000379:methods*; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D055815:Young Adult
keywords: Hemicortical excision; Limb salvage; Parosteal osteosarcoma; Pasteurised autograft; Reconstruction; Resection