title: G-quadruplex unfolding in higher-order DNA structures.
abstract: G-quadruplex unfolding within a sequence of two quadruplex units was characterized by gel electrophoresis, calorimetry and spectroscopy. The obtained results suggest that the kinetics and thermodynamics of the individual quadruplex unfolding are affected by its interaction with other DNA secondary structural elements.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università di Salerno, Via Ponte Don Melillo, 84084, Fisciano (SA), Italy.
authors.forename: Iolanda
authors.initials: I
authors.lastname: Fotticchia
authors.forename: Concetta
authors.initials: C
authors.lastname: Giancola
authors.forename: Luigi
authors.initials: L
authors.lastname: Petraccone
mesh_terms: D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry*; D004591:Electrophoresis, Polyacrylamide Gel; D054856:G-Quadruplexes; D008968:Molecular Conformation
chemical_list: D004247:DNA