title: A novel molecularly imprinted polymer of the specific ionic liquid monomer for selective separation of synephrine from methanol-water media.
abstract: A novel molecularly imprinted polymer (MIP) using the specific ionic liquid (i.e. 1-vinyl-3-carboxymethylimidazolium bromide, 1-vinyl-3-carboxyethylimidazolium bromide, 1-viny-3-carboxybutylimidazolium bromide, or 1-vinyl-3-carboxypentylimidazolium bromide) as functional monomer was prepared via precipitation polymerization, which can be used to selectively separate synephrine (SYN) from methanol-water media. Ionic liquids are facile to be designed with varying the cation or anion, which enables the specific ionic liquid to be effectively designed to be a functional monomer for the preparation of MIP. The MIP showed a good selectivity and high adsorption capacity for SYN in methanol-water media. The adsorption process could be described by the pseudo-first-order model, which meant that the adsorption kinetics described a diffusion-controlled process. The equilibrium data fitted well to the Freundlich model, indicating multilayer adsorption. Finally, the MIP were successfully applied as sorbent to selectively enrich and separate SYN from the extracts of Aurantii Fructus Immaturus with a relatively high recovery (80-90%).
authors.affiliation: Key Laboratory of Poyang Lake Ecology and Bio-Resource Utilization of Ministry of Education, Nanchang University, Nanchang 330031, China. jasperfan@163.com
authors.forename: Jie-Ping
authors.initials: JP
authors.lastname: Fan
authors.forename: Ze-You
authors.initials: ZY
authors.lastname: Tian
authors.forename: Sheng
authors.initials: S
authors.lastname: Tong
authors.forename: Xue-Hong
authors.initials: XH
authors.lastname: Zhang
authors.forename: Yan-Long
authors.initials: YL
authors.lastname: Xie
authors.forename: Rui
authors.initials: R
authors.lastname: Xu
authors.forename: Yu
authors.initials: Y
authors.lastname: Qin
authors.forename: Lie
authors.initials: L
authors.lastname: Li
authors.forename: Jian-Hang
authors.initials: JH
authors.lastname: Zhu
authors.forename: Xiao-Kun
authors.initials: XK
authors.lastname: Ouyang
mesh_terms: D000327:Adsorption; D002957:Citrus / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D052578:Ionic Liquids / Q000737:chemistry*; D054802:Molecular Imprinting; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D013578:Synephrine / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D004365:Drugs, Chinese Herbal; D052578:Ionic Liquids; D011108:Polymers; D013578:Synephrine
keywords: Aurantii Fructus Immaturus; Molecularly imprinted polymers; Separation; Specific ionic liquid; Synephrine