title: Extragastric diseases and Helicobacter pylori.
abstract: In the last year, several diseases from outside of the gastrointestinal tract have been associated with Helicobacter pylori infection. Indeed, this bacterium produces a low-grade inflammatory state, induces molecular mimicry mechanisms, and interferes with the absorbance of nutrients and drugs possibly influencing the occurrence or the evolution of many diseases. In addition to its role in some hematologic conditions, such as immune thrombocytopenic purpura, idiopathic sideropenic anemia, and vitamin B12 deficiency, which were included in the current guidelines, several other conditions such as cardiovascular diseases, diabetes mellitus, hepatobiliary diseases, and neurologic disorders have also shown promising results.
authors.affiliation: Université de Bordeaux, Laboratoire de Bactériologie, Bordeaux, France; Pôle de Gérontologie Clinique, Bordeaux, France; INSERM U853, Bordeaux, France.
authors.forename: Claire
authors.initials: C
authors.lastname: Roubaud Baudron
authors.forename: Francesco
authors.initials: F
authors.lastname: Franceschi
authors.forename: Nathalie
authors.initials: N
authors.lastname: Salles
authors.forename: Antonio
authors.initials: A
authors.lastname: Gasbarrini
mesh_terms: D016481:Helicobacter Infections / Q000276:immunology / Q000382:microbiology*; D016480:Helicobacter pylori / Q000302:isolation & purification / Q000502:physiology*; D006801:Humans; D007154:Immune System Diseases / Q000276:immunology / Q000382:microbiology*; D008107:Liver Diseases / Q000382:microbiology*; D009422:Nervous System Diseases / Q000382:microbiology*
keywords: Alzheimer disease; CagA; ITP; hepatobiliary diseases; inflammation; neurologic disorders; sideropenic anemia