title: The combined use of chlorhexidine and fluoride therapy can reduce the risk for dental caries.
abstract: BACKGROUND
  A randomized clinical trial of anticaries therapies targeted according to risk assessment (caries management by risk assessment). Featherstone JDB, White JM, Hoover CI, Rapozo-Hilo M, Weintraub JA, Wilson RS, Zhan L, Gansky SA. Caries Res 2012;46(2):118-29.
  
  
  METHODS
  Marcelle M. Nascimento, DDS, MS, PhD PURPOSE/QUESTION: The study sought to determine whether the use of preventive and restorative therapies based on individual caries risk for 2 years could reduce caries increment compared to traditional dental care provided at the University of California, San Francisco School of Dentistry (UCSF) SOURCE OF FUNDING: The main research support was provided by NIH/NIDCR and the oral products used in the study were provided by Proctor and Gamble, Omnii Oral Pharmaceuticals and Oral B TYPE OF STUDY/DESIGN: Randomized controlled trial
  
  
  METHODS
  Level 1: Good-quality, patient-oriented evidence
  
  
  METHODS
  Not applicable.
authors.affiliation: Assistant Professor, Department of Restorative Dental Sciences, Division of Operative Dentistry, College of Dentistry, University of Florida, 1395 Center Drive, Room D9-6, PO Box 100415, Gainesville, FL 32610-0415, USA. Tel.: +1 352 273 5858; fax: +1 352 846 1643. Electronic address: mnascimento@dental.ufl.edu.
authors.forename: Marcelle M
authors.initials: MM
authors.lastname: Nascimento
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002327:Cariostatic Agents / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000031:analogs & derivatives*; D003731:Dental Caries / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D012969:Sodium Fluoride / Q000627:therapeutic use*
chemical_list: D000891:Anti-Infective Agents, Local; D002327:Cariostatic Agents; D012969:Sodium Fluoride; D002710:Chlorhexidine