title: The high failure rate of biologic resurfacing of the glenoid in young patients with glenohumeral arthritis.
abstract: BACKGROUND
  The current study evaluated the outcomes of biologic resurfacing of the glenoid using a lateral meniscus allograft or human acellular dermal tissue matrix at intermediate-term follow-up.
  
  
  METHODS
  Forty-five patients (mean age, 42.2 years) underwent biologic resurfacing of the glenoid, and 41 were available for follow-up at a mean of 2.8 years. Lateral meniscal allograft resurfacing was used in 31 patients and human acellular dermal tissue matrix interposition in 10. Postoperative range of motion and clinical outcomes were assessed at the final follow-up.
  
  
  RESULTS
  The overall clinical failure rate was 51.2%. The lateral meniscal allograft cohort had a failure rate of 45.2%, with a mean time to failure of 3.4 years. Human acellular dermal tissue matrix interposition had a failure rate of 70.0%, with a mean time to failure of 2.2 years. Overall, significant improvements were seen compared with baseline with respect to the visual analog pain score (3.0 vs. 6.3), American Shoulder and Elbow Surgeons score (62.0 vs. 36.8), and Simple Shoulder Test score (7.0 vs. 4.0). Significant improvements were seen for forward elevation (106° to 138°) and external rotation (31° to 51°).
  
  
  CONCLUSIONS
  Despite significant improvements compared with baseline values, biologic resurfacing of the glenoid resulted in a high rate of clinical failure at intermediate follow-up. Our results suggest that biologic resurfacing of the glenoid may have a minimal and as yet undefined role in the management of glenohumeral arthritis in the young active patient over more traditional methods of hemiarthroplasty or total shoulder arthroplasty.
authors.affiliation: New York University Hospital for Joint Diseases, New York, NY, USA. Electronic address: eric.strauss@nyumc.org.
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Strauss
authors.affiliation: Midwest Orthopaedics at Rush University Medical Center, Chicago, IL, USA.
authors.forename: Nikhil N
authors.initials: NN
authors.lastname: Verma
authors.affiliation: University Hospital, Case Medical Center, Cleveland, OH, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Salata
authors.affiliation: New York University Hospital for Joint Diseases, New York, NY, USA.
authors.forename: Kevin C
authors.initials: KC
authors.lastname: McGill
authors.affiliation: New York University Hospital for Joint Diseases, New York, NY, USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Klifto
authors.affiliation: New York University Hospital for Joint Diseases, New York, NY, USA.
authors.forename: Gregory P
authors.initials: GP
authors.lastname: Nicholson
authors.affiliation: New York University Hospital for Joint Diseases, New York, NY, USA.
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Cole
authors.affiliation: New York University Hospital for Joint Diseases, New York, NY, USA.
authors.forename: Anthony A
authors.initials: AA
authors.lastname: Romeo
mesh_terms: D062088:Acellular Dermis; D000293:Adolescent; D000328:Adult; D064591:Allografts; D018771:Arthralgia / Q000209:etiology / Q000517:prevention & control; D019643:Arthroplasty, Replacement / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D061165:Glenoid Cavity / Q000601:surgery*; D062785:Hemiarthroplasty / Q000379:methods; D006801:Humans; D008297:Male; D008592:Menisci, Tibial / Q000637:transplantation*; D008875:Middle Aged; D010003:Osteoarthritis / Q000150:complications / Q000601:surgery*; D011182:Postoperative Care; D011859:Radiography; D016059:Range of Motion, Articular; D012086:Reoperation; D012785:Shoulder Joint / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D017211:Treatment Failure; D055815:Young Adult
keywords: Glenohumeral arthritis; Graftjacket; biologic resurfacing; lateral meniscal allograft