title: Late-onset Leclercia adecarboxylata sepsis in a premature neonate.
abstract: The epidemiology, etiology and outcome of neonatal sepsis are changing over time. While monitoring longitudinal trends in neonatal sepsis in our institution, we encountered a case of late-onset neonatal sepsis due to Leclercia adecarboxylata. A Gram-negative rod previously not encountered in the clinical setting, L. adecarboxylata has recently emerged as a human pathogen, primarily in immunosuppressed patients. This report describes the clinical and laboratory features of this case of late-onset L. adecarboxylata sepsis, and reviews significant features of infection associated with this emerging pathogen.
authors.affiliation: Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA.
authors.forename: M U
authors.initials: MU
authors.lastname: Nelson
authors.forename: Y
authors.initials: Y
authors.lastname: Maksimova
authors.forename: V
authors.initials: V
authors.lastname: Schulz
authors.forename: M J
authors.initials: MJ
authors.lastname: Bizzarro
authors.forename: P G
authors.initials: PG
authors.lastname: Gallagher
mesh_terms: D004755:Enterobacteriaceae; D004756:Enterobacteriaceae Infections / Q000175:diagnosis* / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D009102:Multiple Organ Failure / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012127:Respiratory Distress Syndrome, Newborn / Q000150:complications / Q000628:therapy*; D012772:Shock, Septic / Q000175:diagnosis* / Q000628:therapy; D013275:Stomach Rupture / Q000150:complications* / Q000175:diagnosis / Q000628:therapy