title: Muscular sarcoidosis detected by F-18 FDG PET/CT in a hypercalcemic patient.
abstract: Sarcoidosis is a systemic granulomatous disease of unknown etiology that involves many organs, occasionally mimicking malignancy. We herein report a 50-yr-old woman of muscular sarcoidosis of chronic myopathic type, manifested by hypercalcemia and muscle wasting. Besides insignificant hilar lymphadenopathy, her sarcoidosis was confined to generalized atrophic muscles and therefore, F-18 FDG PET/CT alone among conventional imaging studies provided diagnostic clues for the non-parathyroid-related hypercalcemia. On follow-up PET/CT during low-dose steroid treatment, FDG uptake in the muscles disappeared whereas that in the hilar lymph nodes remained. PET/CT may be useful in the evaluation of unexpected disease extent and monitoring treatment response in suspected or known sarcoidosis patients.
authors.affiliation: Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors.forename: Eun Ji
authors.initials: EJ
authors.lastname: Han
authors.forename: Yi Sun
authors.initials: YS
authors.lastname: Jang
authors.forename: In Suk
authors.initials: IS
authors.lastname: Lee
authors.forename: Jong Min
authors.initials: JM
authors.lastname: Lee
authors.forename: Siwon
authors.initials: S
authors.lastname: Kang
authors.forename: Hye Soo
authors.initials: HS
authors.lastname: Kim
mesh_terms: D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D006934:Hypercalcemia / Q000150:complications / Q000175:diagnosis*; D007669:Kidney Calculi / Q000150:complications / Q000175:diagnosis; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008875:Middle Aged; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012507:Sarcoidosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D013256:Steroids / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D013256:Steroids; D019788:Fluorodeoxyglucose F18
keywords: Fluorine-18 Fluorodeoxyglucose; Hypercalcemia; Muscular Disease; Positron Emission Tomography; Sarcoidosis