title: Nickel-catalyzed decarbonylative alkylidenation of phthalimides with trimethylsilyl-substituted alkynes.
abstract: We have developed a nickel-catalyzed transformation, in which phthalimides react with trimethylsilyl-substituted alkynes in the presence of Ni(0)/PMe3/MAD catalyst to provide isoindolinones. The reaction process displays an unusual mechanistic feature-decarbonylation and alkylidenation. The use of both trimethylsilyl-substiuted alkynes and MAD was found to be essential for the transformation with high selectivities.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University , Kyoto 615-8510, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Shiba
authors.forename: Takuya
authors.initials: T
authors.lastname: Kurahashi
authors.forename: Seijiro
authors.initials: S
authors.lastname: Matsubara