title: Potential role of stem cells for neuropathic pain disorders.
abstract: Chronic neuropathic pain is a debilitating disease process associated with several medical disorders. Different from pain caused by inflammation, neuropathic pain is a diffuse pain disorder often found to be recalcitrant to the limited medical treatments available. Intractable nerve pain may benefit from other therapies capable of longer-lasting pain coverage or greater efficacy. A growing number of reports have emerged suggesting a role for stem cells as a cellular delivery source with neuroprotective agents opposing the effects of nerve damage. Here, the authors review the current experimental therapies examining the use of stem cells for the treatment of neuropathic pain disorders.
authors.affiliation: Division of Pediatric Neurosurgery, Texas Children's Hospital, Department of Neurosurgery, Baylor College of Medicine, Houston, Texas 77030, USA. sxvadive@texaschildrens.org
authors.forename: Sudhakar
authors.initials: S
authors.lastname: Vadivelu
authors.forename: Matthew
authors.initials: M
authors.lastname: Willsey
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Curry
authors.forename: John W
authors.initials: JW
authors.lastname: McDonald
mesh_terms: D000818:Animals; D006801:Humans; D009437:Neuralgia / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D033581:Stem Cell Transplantation / Q000379:methods / Q000639:trends*