title: Asymptomatic Schistosoma haematobium infection in a traveler with negative urine microscopy and late seroconversion presumably linked to artemisinin.
abstract: We describe a Schistosoma haematobium infection with asymptomatic eosinophilia, persistently negative urine microscopy, and late seroconversion (7.5 months) in a traveler returning from Mali. After initial negative parasitological tests, travel history led to diagnostic cystoscopy, allowing final diagnosis with urine microscopy after the bladder biopsy. The patient was successfully treated with praziquantel. Difficulties in making the diagnosis of schistosomiasis in asymptomatic returning travelers are discussed; we propose a trial treatment in these cases.
authors.affiliation: Division of Infectious Diseases; Department of Internal Medicine.
authors.forename: Nicolás
authors.initials: N
authors.lastname: Martínez-Calle
authors.forename: Ignacio
authors.initials: I
authors.lastname: Pascual
authors.forename: Manuel
authors.initials: M
authors.lastname: Rubio
authors.forename: Rafael
authors.initials: R
authors.lastname: Carias
authors.forename: José Luis
authors.initials: JL
authors.lastname: Del Pozo
authors.forename: José Ramón
authors.initials: JR
authors.lastname: Yuste
mesh_terms: D000328:Adult; D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000009:adverse effects; D037621:Artemisinins / Q000008:administration & dosage / Q000009:adverse effects*; D058070:Asymptomatic Diseases; D003558:Cystoscopy / Q000379:methods; D057210:Delayed Diagnosis; D004802:Eosinophilia / Q000209:etiology*; D006801:Humans; D008297:Male; D008302:Mali; D011223:Praziquantel / Q000008:administration & dosage*; D012548:Schistosoma haematobium / Q000187:drug effects / Q000302:isolation & purification; D012552:Schistosomiasis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology / Q000503:physiopathology; D012698:Serologic Tests / Q000379:methods; D014195:Travel; D016896:Treatment Outcome; D016482:Urinalysis / Q000379:methods
chemical_list: D000871:Anthelmintics; D000890:Anti-Infective Agents; D037621:Artemisinins; D011223:Praziquantel; C031327:artemisinin