title: An updated review of sepsis for the anesthesiologist.
abstract: Severe sepsis and septic shock continue to be among of the leading causes of death in intensive care unit patients, carrying an estimated mortality rate between 30% and 50%. This article provides an evidence-based focused review of sepsis, including an update on management strategies based on the most recent guidelines published by the Surviving Sepsis Campaign.
authors.affiliation: 1University of Rochester, Rochester, NY, USA.
authors.forename: Konstantine N
authors.initials: KN
authors.lastname: Tzimas
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Papadakos
mesh_terms: D000776:Anesthesiology / Q000379:methods; D019317:Evidence-Based Medicine; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data; D017410:Practice Guidelines as Topic; D018805:Sepsis / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D012772:Shock, Septic / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*
keywords: anticoagulants; antithrombosis; circulatory; coagulopathy; critical care; inflammation; inotropic agents; monitoring; outcome; thrombin