title: Association of early-onset androgenetic alopecia and metabolic syndrome in Thai men: a case-control study.
abstract: BACKGROUND
  There are many studies of the association between early-onset androgenetic alopecia (AGA) and metabolic syndrome (MS), which is known to increase the risk of cardiovascular diseases. However the results are inconsistent. There is no study in a Thai population.
  
  
  OBJECTIVE
  To evaluate the association of early-onset AGA and metabolic syndrome in Thai male patients.
  
  
  METHODS
  Patients were recruited from the check-up clinic. There were 80 male subjects: 40 with a diagnosis of early-onset AGA (before 35 years of age) and 40 control subjects without alopecia. Data from medical records, self-administered forms, and interview were collected and analyzed.
  
  
  RESULTS
  Patients with early-onset AGA had the 3.48-fold higher risk of metabolic syndrome than in a control group (p = 0.015, odd ratio = 3.48, 95% confidence interval = 1.25-9.75). There was no relationship between AGA severity and metabolic syndrome (p = 0.629). There were no significant differences between the groups in terms of metabolic syndrome parameter
  
  
  CONCLUSIONS
  The present study found the association between early onset A GA and metabolic syndrome in Thai men. Early detection of metabolic syndrome in this population may be useful to prevent cardiovascular diseases.
authors.affiliation: Department of Dermatology, School of Anti-aging and Regenerative Medicine, Mae Fah Luang Hospital (Bangkok), Bangkok, Thailand.
authors.forename: Nopparat
authors.initials: N
authors.lastname: Pengsalae
authors.forename: Chuchai
authors.initials: C
authors.lastname: Tanglertsampan
authors.forename: Thanapat
authors.initials: T
authors.lastname: Phichawong
authors.forename: Saridpong
authors.initials: S
authors.lastname: Lee
mesh_terms: D000328:Adult; D017668:Age of Onset; D000505:Alopecia / Q000453:epidemiology*; D016022:Case-Control Studies; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008875:Middle Aged; D013785:Thailand / Q000453:epidemiology