title: Ceftaroline for meticillin-resistant Staphylococcus aureus bacteraemia: case series and review of the literature.
abstract: Data regarding ceftaroline use for meticillin-resistant Staphylococcus aureus bacteraemia (MRSAB) are lacking. Here we review the outcomes of 31 patients with MRSAB treated with ceftaroline, including 9 patients with endocarditis. Clinical success was observed in 23 patients (74.2%). Adverse events associated with prolonged therapy were rare and included eosinophilic pneumonia, rash and diarrhoea. We conclude that ceftaroline can be used for MRSAB.
authors.affiliation: Wright State University Boonshoft School of Medicine, Miami Valley Hospital, 128 East Apple Street, Weber CHE 2nd Floor, Dayton, OH 45409, USA. Electronic address: haralampie1909@gmail.com.
authors.forename: Hari M
authors.initials: HM
authors.lastname: Polenakovik
authors.forename: Craig M
authors.initials: CM
authors.lastname: Pleiman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology; D002511:Cephalosporins / Q000627:therapeutic use*; D064420:Drug-Related Side Effects and Adverse Reactions / Q000453:epidemiology / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D016896:Treatment Outcome; D055815:Young Adult; D000097583:Ceftaroline
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D000097583:Ceftaroline
keywords: Bacteraemia; Ceftaroline; Endocarditis; MRSA; Meticillin-resistant Staphylococcus aureus