title: Accuracy in prescriptions compounded by pharmacy students.
abstract: Most compounded prescriptions are not analyzed to determine the accuracy of the employed instruments and procedures. The assumption is that the compounded prescription will be +/- 5% the labeled claim. Two classes of School of Pharmcacy students who received repeated instruction and supervision on proper compounding techniques and procedures were assessed to determine their accuracy of compounding a diphenhydramine hydrochloride prescription. After two attempts, only 62% to 68% of the students could compound the prescription within +/- 5% the labeled claim; but 84% to 96% could attain an accuracy of +/- 10%. The results suggest that an accuracy of +/- 10% labeled claim is the least variation a pharmacist can expect when extemporaneously compounding prescriptions.
authors.affiliation: Pharmaceutical Care Laboratories, Division of Pharmaceutics, School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC.
authors.forename: R P
authors.initials: RP
authors.lastname: Shrewsbury
authors.forename: K H
authors.initials: KH
authors.lastname: Deloatch