title: The effects of strict salt control on blood pressure and cardiac condition in end-stage renal disease: prospective-study.
abstract: BACKGROUND
  Overhydration is the main contributory factor of left ventricular hypertrophy and closely associated with cardiovascular events in end stage renal disease (ESRD) patients. The aim of this prospective-study was to investigate the impact of strict salt and volume control on hypertension and cardiac condition in ESRD patients.
  
  
  METHODS
  A total of 12 peritoneal dialysis (PD) and 15 prevalent hemodialysis (HD) patients were enrolled. All patients either PD or HD were allocated to intervention of strict salt restriction according to basal hydration state of empty abdomen in PD and midweek predialysis HD which were estimated by body composition monitor (BCM) and echocardiography.
  
  
  RESULTS
  Mean ages were 48.3 ± 16.7 years for PD, and 48.8 ± 18 for HD patients. Extracellular water/height was 10.04 ± 2.70 and 10.39 ± 1.53 L/m in PD and HD groups. Systolic blood pressures decreased in PD and HD from 133.1 ± 28 and 147.3 ± 28.5 to 114.8 ± 16.5 and 119.3 ± 12.1 mmHg, respectively, (p < 0.00). IDKA/DW were decreased from 3.26 ± 1.6 to 2.97 ± 1.63 % in HD group (p > 0.05). LVMI and LAI were not increased in both groups.
  
  
  CONCLUSIONS
  Strict salt and volume control in ESRD patients after assessment of hydration status with either using BCM or echocardiography provides better management of volume control leading to more precise cardiovascular protection.
authors.affiliation: Department of Nephrology, Bulent Ecevit University , Zonguldak , Turkey .
authors.forename: Kemal
authors.initials: K
authors.lastname: Magden
authors.forename: Ender
authors.initials: E
authors.lastname: Hur
authors.forename: Gursel
authors.initials: G
authors.lastname: Yildiz
authors.forename: Sennur Budak
authors.initials: SB
authors.lastname: Kose
authors.forename: Selahattin
authors.initials: S
authors.lastname: Bicak
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Yildirim
authors.forename: Muhammet Rasit
authors.initials: MR
authors.lastname: Sayin
authors.forename: Soner
authors.initials: S
authors.lastname: Duman
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D004039:Diet, Sodium-Restricted; D006801:Humans; D006973:Hypertension / Q000178:diet therapy* / Q000209:etiology; D017379:Hypertrophy, Left Ventricular / Q000178:diet therapy* / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000150:complications*; D008875:Middle Aged; D011446:Prospective Studies