title: CENP-E hangs on at dynamic microtubule ends.
abstract: During mitosis, kinetochores attach to microtubule plus ends, thus allowing dynamic microtubules to properly segregate chromosomes. How this type of 'end-on' attachment between microtubule plus ends and kinetochores is formed and maintained is unclear. CENP-E, a kinesin-7 family member, is now shown to have a role in associating kinetochores with dynamic microtubule plus ends.
authors.affiliation: Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA.
authors.forename: Melissa K
authors.initials: MK
authors.lastname: Gardner
mesh_terms: D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism*; D006801:Humans; D018386:Kinetochores / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D008938:Mitosis / Q000235:genetics*
chemical_list: D002868:Chromosomal Proteins, Non-Histone; C068688:centromere protein E