title: [Relationship between vitamin D status and bone mineral density in Croatian postmenopausal women].
abstract: The aim of the study was to investigate correlation of vitamin D status meassured as 25-hydoxyvitamin D (25(OH)D) concentration with bone mineral density (BMD) in Croatian postmenopausal women. This study was based on the sample of 194 adult, postmenopausal women aged 50 years or over from Croatia. Assessment of 25(OH)D concentration and BMD by dual-energy xray absorptiometry (DXA) was performed to all participants. The average age of the participants in this study was 60.6 years. The average menopause duration was 11.4 years. Among the included participants only 13.9% of women complied with diagnostic criteria for osteoporosis. Mean serum concentration of 25(OH)D was 49.1 nmol/L (+/-17.1 SD). The prevalence of severe vitamin D deficiency was significantly higher in participants with osteoporosis compared with participants with normal BMD (<30 nmol/L; 29.6% vs. 9.8%). Correlation between serum 25(OH)D concentration and BMD was significant and positive at the proximal femur (r=0.18; p=0.026), and at the femoral neck (r=0.15; p<0.001). The results of this study indicate significant and positive correlation between serum 25(OH)D concentration and BMD meassured at the proximal femur and at the femoral neck in Croatian postmenopausal women.
authors.affiliation: Klinika za reumatske bolesti i rehabilitaciju Klinicki bolnicki centar Zagreb. nadica_laktasic@yahoo.com
authors.forename: Nadica
authors.initials: N
authors.lastname: Laktasić-Zerjavić
authors.forename: Kresimir
authors.initials: K
authors.lastname: Rukavina
authors.forename: Durdica
authors.initials: D
authors.lastname: Babić-Naglić
authors.forename: Bozidar
authors.initials: B
authors.lastname: Curković
authors.forename: Branimir
authors.initials: B
authors.lastname: Anić
authors.forename: Dragica
authors.initials: D
authors.lastname: Soldo-Juresa
mesh_terms: D000368:Aged; D015519:Bone Density; D017523:Croatia / Q000453:epidemiology; D005260:Female; D005269:Femur / Q000033:anatomy & histology; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D017698:Postmenopause; D015995:Prevalence; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000150:complications* / Q000453:epidemiology
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D