title: Chronic myeloid leukemia following colon cancer treatment: A case report and literature review.
abstract: BACKGROUND
  Solid tumors may occur in 3% of the patients with chronic myeloid leukemia (CML). In this paper, we presented a case of CML following treatment of colon cancer.
  
  
  METHODS
  A 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. Following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. Then he developed BCR-ABL positive CML. With Imatinib 400 mg/day, he achieved hematologic response but died because of progressive colon cancer.
  
  
  CONCLUSIONS
  This article emphasizes that there is a possibility for etiologic correlation between CML and chemotherapeutic agents in solid cancers.
authors.affiliation: Department of Hematology and Medical Oncology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Vakili-Sadeghi
authors.forename: Mohammadhasan
authors.initials: M
authors.lastname: Omranpour
keywords: Chemotherapy; Chronic myelogenous leukemia; Colon cancer