title: Motor cortex activation by H-coil and figure-8 coil at different depths. Combined motor threshold and electric field distribution study.
abstract: OBJECTIVE
  To compare the ability of an H-coil and figure-8 coil to stimulate different motor cortex regions.
  
  
  METHODS
  The resting (rMT) and active (aMT) motor thresholds were measured for the right hand APB and leg AHB muscles in 10 subjects, using an H-coil and a figure-8 coil. The electric field distribution induced by the coils was measured in a head model. The combination of the hand and leg MTs with the field measurements was used to determine the depth of hand and leg motor areas via the intersection points.
  
  
  RESULTS
  The rMT and aMT of both APB and AHB were significantly lower for the H-coil. The ratio and difference between the leg and hand rMT and aMT were significantly lower for the H-Coil. Electric field measurements revealed significantly more favorable depth profile and larger volume of stimulation for the H-coil. The averaged intersection for the APB was at a distance from coil of 1.83±0.54cm and at an intensity of 97.8±21.4V/m, while for the AHB it was at a distance of 2.73±0.44cm and at an intensity of 118.6±21.3V/m.
  
  
  CONCLUSIONS
  The results suggest a more efficient activation of deeper motor cortical regions using the H-coil.
  
  
  CONCLUSIONS
  The combined evaluation of MTs by H- and figure-8 coils allows measurement of the individual depth of different motor cortex regions. This could be helpful for optimizing stimulation parameters for TMS treatment.
authors.affiliation: Department of Life Sciences, Ben-Gurion University, Beer Sheva, Israel. Electronic address: Yiftach@brainsway.com.
authors.forename: Yiftach
authors.initials: Y
authors.lastname: Roth
authors.affiliation: Department of Life Sciences, Ben-Gurion University, Beer Sheva, Israel.
authors.forename: Gaby S
authors.initials: GS
authors.lastname: Pell
authors.affiliation: Department of Neurosurgery, Rambam Health Care Campus and B. Rappaport, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: Andrei V
authors.initials: AV
authors.lastname: Chistyakov
authors.affiliation: Department of Neurosurgery, Rambam Health Care Campus, Haifa, Israel; Department of Neurology, Rambam Health Care Campus, Haifa, Israel.
authors.forename: Alon
authors.initials: A
authors.lastname: Sinai
authors.affiliation: Department of Life Sciences, Ben-Gurion University, Beer Sheva, Israel.
authors.forename: Abraham
authors.initials: A
authors.lastname: Zangen
authors.affiliation: Department of Neurosurgery, Rambam Health Care Campus and B. Rappaport, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: Menashe
authors.initials: M
authors.lastname: Zaaroor
mesh_terms: D000328:Adult; D001931:Brain Mapping; D019054:Evoked Potentials, Motor / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008959:Models, Neurological; D009044:Motor Cortex / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*; D050781:Transcranial Magnetic Stimulation / Q000295:instrumentation / Q000379:methods*
keywords: Electric field; H-coil; Hand motor cortex; Leg motor cortex; Motor threshold; Transcranial magnetic stimulation