title: [Neutrophils expression of adhesion molecules in diabetic nephropaty patients].
abstract: CD11b and CD54 expression on neutrophils in patients with diabetic nephropathy (DN), arterial hypertension patients and healthy donors were examined. Development of DN associates with an increase of the number of CD11b and CD54 positive cells and violation of cellular co-operation. In the conditions of diabetic microenvironment expression of adhesion molecules rises substantially, what may characterized the mechanism of connection between hyperglycemia and vascular and tissues injury at DN. Authentication of morphological and biochemical markers of intercellular co-operation must in a prospect assist the deeper understanding of pathogenic mechanisms of DN.
authors.forename: T D
authors.initials: TD
authors.lastname: Shcherban'
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D039481:CD11b Antigen / Q000096:biosynthesis / Q000276:immunology; D015815:Cell Adhesion Molecules / Q000096:biosynthesis* / Q000097:blood; D003928:Diabetic Nephropathies / Q000097:blood* / Q000276:immunology; D005260:Female; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000096:biosynthesis / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D039481:CD11b Antigen; D015815:Cell Adhesion Molecules; D018799:Intercellular Adhesion Molecule-1