title: Chromium level of salvaged blood in patients undergoing revision hip arthroplasty.
abstract: PURPOSE. To evaluate the chromium level of the salvaged blood in patients undergoing revision total hip arthroplasty (THA). METHODS. Records of 7 women and one man aged 54 to 83 (mean, 64.3) years who underwent revision THA for aseptic loosening of the acetabular component (n=6), osteolysis of the acetabulum (n=1), or migration of the outer head (n=1) were reviewed, as were 2 controls who underwent primary THA. The initial THA entailed a metal-on-metal prosthesis (n=4), a metal-on-polyethylene prosthesis (n=3), and a bipolar head prosthesis (n=1). Chromium levels in the preoperative peripheral blood and intraoperative salvaged blood were measured using atomic absorption analysis. RESULTS. For controls and the patient with a bipolar head prosthesis, the mean chromium level in salvaged blood was 0.4 (range, 0.2-0.6) micrograms/l, which was significantly lower than that in the remaining 7 patients undergoing revision THA (mean, 5.6 micrograms/l; range, 1.2-9.8 micrograms/l). CONCLUSION. Salvaged blood of patients with a metal-on-metal prosthesis undergoing revision THA contained higher levels of chromium.
authors.affiliation: Department of Orthopaedic Surgery, Juntendo University School of Medicine, Tokyo, Japan.
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Maezawa
authors.forename: Takahito
authors.initials: T
authors.lastname: Yuasa
authors.forename: Kentaro
authors.initials: K
authors.lastname: Aritomi
authors.forename: Seiki
authors.initials: S
authors.lastname: Ogawa
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Maruyama
authors.forename: Masahiko
authors.initials: M
authors.lastname: Nozawa
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kaneko
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D001672:Biocompatible Materials; D002857:Chromium / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008670:Metals; D008875:Middle Aged; D057725:Operative Blood Salvage; D011475:Prosthesis Failure; D012086:Reoperation
chemical_list: D001672:Biocompatible Materials; D008670:Metals; D002857:Chromium
keywords: arthroplasty, replacement, hip; chromium; operative blood salvage; reoperation