title: LongevityMap: a database of human genetic variants associated with longevity.
abstract: Understanding the genetic basis of human longevity remains a challenge but could lead to life-extending interventions and better treatments for age-related diseases. Toward this end we developed the LongevityMap (http://genomics.senescence.info/longevity/), the first database of genes, loci, and variants studied in the context of human longevity and healthy ageing. We describe here its content and interface, and discuss how it can help to unravel the genetics of human longevity.
authors.affiliation: The Shraga Segal Department of Microbiology, Immunology and Genetics, Center for Multidisciplinary Research on Aging, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel; Judea Regional Research and Development Center, Carmel 90404, Israel.
authors.forename: Arie
authors.initials: A
authors.lastname: Budovsky
authors.forename: Thomas
authors.initials: T
authors.lastname: Craig
authors.forename: Jingwei
authors.initials: J
authors.lastname: Wang
authors.forename: Robi
authors.initials: R
authors.lastname: Tacutu
authors.forename: Attila
authors.initials: A
authors.lastname: Csordas
authors.forename: Joana
authors.initials: J
authors.lastname: Lourenço
authors.forename: Vadim E
authors.initials: VE
authors.lastname: Fraifeld
authors.forename: João Pedro
authors.initials: JP
authors.lastname: de Magalhães
mesh_terms: D001483:Base Sequence; D030541:Databases, Genetic; D014644:Genetic Variation; D006801:Humans; D008136:Longevity / Q000235:genetics*; D008969:Molecular Sequence Data
keywords: GWAS; ageing; genetics; humans; lifespan; polymorphisms