title: [Do anti-inflammatory drugs worsen odontogenic cervico-facial cellulitis?].
abstract: OBJECTIVE
  The aim of this prospective study was to determine the influence of anti-inflammatory drugs on the severity of odontogenic cellulitis in patients admitted to our hospital emergency unit.
  
  
  METHODS
  The study was made from April 30 to October 31 2006. The clinical and pharmacological data was prospectively collected at admission, during hospitalization, and during systematic follow-up. We first studied the whole population and then compared the two groups: patients having received anti-inflammatory drugs before admission or not.
  
  
  RESULTS
  Two hundred and sixty-seven patients were included. The only severity criterion significantly different between the two groups was spreading of cervical lymphangitis (P = 0.028). None of the four studied parameters was identified as a risk factor for spreading of cervical lymphangitis in multivariate analysis: anti-inflammatory use (OR = 5.99, 95%CI [0.71-50.88]), alcohol abuse (OR = 4.00, 95%CI [0.66-24.12]), dental hygiene (OR = 1.53, 95%CI [0.36-6.56]), and tobacco use (OR = 0.27, 95%CI [0.57-1.28]).
  
  
  CONCLUSIONS
  The use of anti-inflammatory drugs during the initial phase of an odontogenic infection was not related to the severity of infection.
authors.affiliation: Department of oral and maxillofacial surgery, Roger-Salengro Hospital, CHU de Lille, rue Emile-Laine, 59000 Lille, France; UDSL, université Lille Nord de France, 59000 Lille, France. Electronic address: romain.nicot@gmail.com.
authors.forename: R
authors.initials: R
authors.lastname: Nicot
authors.forename: C
authors.initials: C
authors.lastname: Hippy
authors.forename: C
authors.initials: C
authors.lastname: Hochart
authors.forename: A
authors.initials: A
authors.lastname: Wiss
authors.forename: A
authors.initials: A
authors.lastname: Brygo
authors.forename: S
authors.initials: S
authors.lastname: Gautier
authors.forename: J
authors.initials: J
authors.lastname: Caron
authors.forename: J
authors.initials: J
authors.lastname: Ferri
authors.forename: G
authors.initials: G
authors.lastname: Raoul
mesh_terms: D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002481:Cellulitis / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D005145:Face; D005260:Female; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009333:Neck; D010343:Patient Admission / Q000706:statistics & numerical data; D009057:Stomatognathic Diseases / Q000150:complications* / Q000453:epidemiology / Q000628:therapy; D055815:Young Adult
chemical_list: D000893:Anti-Inflammatory Agents
keywords: Anti-inflammatoires; Anti-inflammatory agent; Cellulite; Cellulitis; Infection