title: [Evolution of the clinical presentation of renal cancer. Fifteen years experience].
abstract: OBJECTIVE
  To evaluate the evolution of the clinical presentation of this malignancy over time, and its possible prognostic repercussions.
  
  
  METHODS
  A retrospective study of 538 patients subjected to surgery due to renal cancer in our hospital during the period 1995-2011. An analysis was made of the evolution of the clinical manifestations at the time of diagnosis, stratifying the results by years during four time periods.
  
  
  RESULTS
  At the time of diagnosis, 53,4% of the patients were asymptomatic for 1995-1999 and 72% in the period 2008-2011. Pain is the symptom that occurs most frequently (18.8%) followed by hematuria (15.4% ). The proportion of symptomatic patients increases in relation to stage and histopathological grade.
  
  
  CONCLUSIONS
  The clinical presentation of renal cancer has evolved over the years, not in terms of symptoms, which when present are still similar, but in terms of their incidence.
authors.affiliation: Servicios de Urología y Medicina Preventiva. Hospital Universitario La Paz. Madrid. España.
authors.forename: Sonia
authors.initials: S
authors.lastname: Perez Gonzalez
authors.forename: Alfredo
authors.initials: A
authors.lastname: Aguilera Bazán
authors.forename: Carlos Alvaro
authors.initials: CA
authors.lastname: Polo Lopez
authors.forename: Beatriz
authors.initials: B
authors.lastname: Bañuelos Marco
authors.forename: Jesus
authors.initials: J
authors.lastname: Diaz
authors.forename: Javier
authors.initials: J
authors.lastname: De la Peña Barthel
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D015897:Comorbidity; D018450:Disease Progression; D005260:Female; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010146:Pain / Q000209:etiology; D012189:Retrospective Studies; D012737:Sex Factors