title: Gold nanoparticles coated polystyrene/reduced graphite oxide microspheres with improved dispersibility and electrical conductivity for dopamine detection.
abstract: Gold nanoparticles coated polystyrene/reduced graphite oxide (AuNPs@PS/RGO) microspheres have been successfully prepared via a facile process, and the decorative gold nanoparticles could prevent the aggregation of RGO by electrostatic repulsive interaction, and lead to high dispersibility of the composite. The prepared composite has a highly increased conductivity of 129Sm(-1) due to the unique electrical properties of citrate reduced gold nanoparticles. Being employed as an electrochemical sensor for detection of dopamine, the modified electrode exhibits remarkable sensitivity (3.44μA/μM) and lower detection limit (5nM), with linear response in a range of 0.05-20μM. Moreover, valid response to dopamine obtained in present work also indicates the prospective performances of AuNPs@PS/RGO microspheres to other biological molecules, such as nucleic acids, proteins and enzymes.
authors.affiliation: School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Qian
authors.forename: Chenfei
authors.initials: C
authors.lastname: Yu
authors.forename: Shishan
authors.initials: S
authors.lastname: Wu
authors.forename: Jian
authors.initials: J
authors.lastname: Shen
mesh_terms: D001205:Ascorbic Acid / Q000032:analysis; D004298:Dopamine / Q000032:analysis*; D004553:Electric Conductivity; D055664:Electrochemical Techniques / Q000379:methods*; D006046:Gold; D006108:Graphite / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D008863:Microspheres; D010084:Oxidation-Reduction; D011137:Polystyrenes; D014527:Uric Acid / Q000032:analysis
chemical_list: D011137:Polystyrenes; D014527:Uric Acid; D006046:Gold; D006108:Graphite; D001205:Ascorbic Acid; D004298:Dopamine
keywords: Biosensor; Dispersibility; Gold nanoparticles; Polystyrene; Reduced graphite oxide