title: Recurrence of a functional adrenocortical oncocytoma of borderline malignant potential showing high FDG uptake on 18F-FDG PET/CT.
abstract: Adrenocortical oncocytoma is a very rare tumor, which is not malignant and nonfunctioning in most cases. We report a case of a 53-year-old male with a 9.8 cm sized hyperfunctioning, well-encapsulated adrenal mass, which exhibited by high FDG uptake on a PET/CT scan. The patient had complained of symptoms of Cushing's syndrome for 4 months. Laparoscopic adrenalectomy was performed and the mass was pathologically confirmed as adrenocortical oncocytoma of uncertain malignant potential. Four years after surgery, the tumor recurred with distant metastases, which was proven by subsequent biopsy. 18F-FDG PET/CT also showed hypermetabolism in the recurred tumor and multiple metastatic lesions. Adrenocortical oncocytoma of borderline malignant potential with high FDG uptake may require long-term follow-up with clinical, hormonal, and imaging evaluations.
authors.affiliation: Department of Nuclear Medicine, Kyungpook National University School of Medicine and Hospital, 807 Hogukno, Buk-gu, Daegu, 702-210, Republic of Korea.
authors.forename: Seung Hyun
authors.initials: SH
authors.lastname: Son
authors.forename: Sang-Woo
authors.initials: SW
authors.lastname: Lee
authors.forename: Bong-Il
authors.initials: BI
authors.lastname: Song
authors.forename: Yun-Jin
authors.initials: YJ
authors.lastname: Jang
authors.forename: Ji-Young
authors.initials: JY
authors.lastname: Park
authors.forename: Shin Young
authors.initials: SY
authors.lastname: Jeong
authors.forename: Byeong-Cheol
authors.initials: BC
authors.lastname: Ahn
authors.forename: Jaetae
authors.initials: J
authors.lastname: Lee
mesh_terms: D018249:Adenoma, Oxyphilic / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology*; D000306:Adrenal Cortex Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology*; D001692:Biological Transport; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D012008:Recurrence; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18