title: Should ischemia be the main target in selecting a percutaneous coronary intervention strategy?
abstract: Contemporary studies have demonstrated that revascularization therapy targeted at coronary anatomy alone has not been able to consistently yield significant prognostic clinical outcomes. The practice of specific ischemia-targeted intervention for coronary disease in certain study populations has, however, produced important and reproducible clinical outcomes in terms of both symptoms and prognosis. We discuss the recent evidence and propose an ischemia-driven approach for selecting a percutaneous coronary intervention strategy.
authors.affiliation: Wessex Cardiothoracic Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
authors.forename: Kristel
authors.initials: K
authors.lastname: Longman
authors.forename: Nick
authors.initials: N
authors.lastname: Curzen
mesh_terms: D003324:Coronary Artery Disease / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D017202:Myocardial Ischemia / Q000473:pathology / Q000628:therapy; D009204:Myocardial Revascularization / Q000379:methods*; D062645:Percutaneous Coronary Intervention / Q000379:methods*; D011379:Prognosis; D015203:Reproducibility of Results; D016896:Treatment Outcome