title: [Immunophenotypic characteristic of dendritic cells in bronchial asthma in conditions of extract opisthorchis felineus in vitro].
abstract: This work shows comparative characteristics of immunogenic properties of the extract of Opisthorchis felineus in different severity of asthma using antigen presenting dendritic cells in vitro. New data on the effect of Opisthorchis felineus on the expression of surface markers of dendritic cells (CD209, HLA-DR, CD83, CD86) were received. Pronounced expression of CD209, CD86 and HLA-DR on the surface of dendritic cells in mild and severe asthma compared with healthy individuals was shown. In the stimulation of dendritic cells with extract Opisthorchis felineus in vitro weakening of CD86 expression in mild and in severe asthma was found. CD86 molecule may be a regulatory factor in the co-stimulation of dendritic cells which
authors.forename: E É
authors.initials: EÉ
authors.lastname: Kremer
authors.forename: L M
authors.initials: LM
authors.lastname: Ogorodova
authors.forename: N A
authors.initials: NA
authors.lastname: Kirillova
authors.forename: K V
authors.initials: KV
authors.lastname: Khvorilova
authors.forename: T V
authors.initials: TV
authors.lastname: Perevozchikova
authors.forename: E A
authors.initials: EA
authors.lastname: Faĭt
mesh_terms: D000818:Animals; D017951:Antigen Presentation / Q000276:immunology; D000947:Antigens, Helminth; D000954:Antigens, Surface / Q000032:analysis; D001249:Asthma / Q000209:etiology / Q000276:immunology* / Q000473:pathology; D051940:B7-2 Antigen / Q000032:analysis*; D003713:Dendritic Cells / Q000276:immunology; D006801:Humans; D018448:Models, Immunological; D009891:Opisthorchis / Q000276:immunology*; D012720:Severity of Illness Index
chemical_list: D000947:Antigens, Helminth; D000954:Antigens, Surface; D051940:B7-2 Antigen