title: Non spherical polyvinyl alcohol versus gelatin sponge particles for uterine artery embolization for symptomatic fibroids.
abstract: OBJECTIVE
  To compare clinical and magnetic resonance imaging (MRI) outcomes after uterine artery embolization (UAE) with non spherical polyvinyl alcohol (nPVA) versus gelatin sponge particles.
  
  
  METHODS
  During ten months, from Jan 2011 to Oct 2011, 60 patients underwent UAE in a standardized manner. nPVA (n = 30) or gelatin sponge particles (n = 30) were used in all patients. Pelvic MRI and clinical symptoms were reviewed before and after the procedure. Changes in tumor, uterine volume and infarction rate of dominant tumor were assessed using MRI.
  
  
  RESULTS
  At three months after embolization, the outcome data were collected. The improvement of the mean bleeding score was more pronounced with gelatin sponge particles than with nPVA particles (p = 0.035). The mean volume reduction rate and infarction rate of dominant fibroid were 47.9 ± 20.8%, 97.7 ± 5.2% and 60.2 ± 18.1, 96 ± 7.0% after UAE with nPVA compared to gelatin sponge particles, respectively.
  
  
  CONCLUSIONS
  This study showed the superiority of gelatin sponge particles over nPVA in terms of improvement of mean bleeding score and volume reduction rate of dominant fibroid at three months follow-up after UAE, although the infarction rate of dominant fibroid was similar across groups at three months.
authors.affiliation: Department of Radiology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine , Changwon , Korea.
authors.forename: Yun Gyu
authors.initials: YG
authors.lastname: Song
authors.forename: Hong
authors.initials: H
authors.lastname: Jang
authors.forename: Keung Do
authors.initials: KD
authors.lastname: Park
authors.forename: Man Deuk
authors.initials: MD
authors.lastname: Kim
authors.forename: Chang-Woon
authors.initials: CW
authors.lastname: Kim
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D005781:Gelatin Sponge, Absorbable / Q000008:administration & dosage; D006801:Humans; D007889:Leiomyoma / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011142:Polyvinyl Alcohol / Q000008:administration & dosage; D011446:Prospective Studies; D016896:Treatment Outcome; D055357:Uterine Artery Embolization / Q000379:methods*; D014594:Uterine Neoplasms / Q000628:therapy*
chemical_list: D011142:Polyvinyl Alcohol