title: Advances in diagnosis and spatial analysis of cysticercosis and taeniasis.
abstract: Human cysticercosis, caused by accidental ingestion of eggs of Taenia solium, is one of the most pathogenic helminthiases and is listed among the 17 WHO Neglected Tropical Diseases. Controlling the life-cycle of T. solium between humans and pigs is essential for eradication of cysticercosis. One difficulty for the accurate detection and identification of T. solium species is the possible co-existence of two other human Taenia tapeworms (T. saginata and T. asiatica, which do not cause cysticercosis in humans). Several key issues for taeniasis/cysticercosis (T/C) evidence-based epidemiology and control are reviewed: (1) advances in immunological and molecular tools for screening of human and animals hosts and identification of Taenia species, with a focus on real-time detection of taeniasis carriers and infected animals in field community screenings, and (2) spatial ecological approaches that have been used to detect geospatial patterns of case distributions and to monitor pig activity and behaviour. Most recent eco-epidemiological studies undertaken in Sichuan province, China, are introduced and reviewed.
authors.affiliation: Chrono-environment Lab, UMR 6249 University of Franche-Comté and CNRS, Besançon, France.
authors.forename: Francis
authors.initials: F
authors.lastname: Raoul
authors.forename: Tiaoying
authors.initials: T
authors.lastname: Li
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Sako
authors.forename: Xingwang
authors.initials: X
authors.lastname: Chen
authors.forename: Changping
authors.initials: C
authors.lastname: Long
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yanagida
authors.forename: Yunfei
authors.initials: Y
authors.lastname: Wu
authors.forename: Minoru
authors.initials: M
authors.lastname: Nakao
authors.forename: Munehiro
authors.initials: M
authors.lastname: Okamoto
authors.forename: Philip S
authors.initials: PS
authors.lastname: Craig
authors.forename: Patrick
authors.initials: P
authors.lastname: Giraudoux
authors.forename: Akira
authors.initials: A
authors.lastname: Ito
mesh_terms: D000818:Animals; D000947:Antigens, Helminth / Q000302:isolation & purification*; D002681:China / Q000453:epidemiology; D003551:Cysticercosis / Q000175:diagnosis* / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary*; D018509:DNA, Helminth / Q000302:isolation & purification*; D005243:Feces / Q000469:parasitology; D006801:Humans; D017720:Molecular Epidemiology; D058069:Neglected Diseases; D062206:Spatial Analysis; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000635:transmission; D013621:Taenia / Q000145:classification / Q000302:isolation & purification*
chemical_list: D000947:Antigens, Helminth; D018509:DNA, Helminth