title: Breast cancer bone metastases: it's all about the neighborhood.
abstract: In order to establish themselves in distal sites, metastatic cancer cells need to acquire organ-specific traits. Zhang et al. provide evidence in breast cancer that a tumor cell's acquisition of properties for successful bone metastasis is influenced by signals from the stroma of the primary tumor.
authors.affiliation: Department of Medicine, Division of Endocrinology, Indiana University, Indianapolis, IN 46202, USA. Electronic address: tguise@iu.edu.
authors.forename: Theresa A
authors.initials: TA
authors.lastname: Guise
mesh_terms: D000818:Animals; D001859:Bone Neoplasms / Q000556:secondary*; D001943:Breast Neoplasms / Q000473:pathology*; D006801:Humans; D009362:Neoplasm Metastasis; D015398:Signal Transduction