title: The first chiral Raman spectrum report of a protein: a perspective of 20 years.
abstract: In 1990 the article on the first Raman spectrum of a protein using a circularly polarized light as excitation radiation, authored by the group of Prof. L. Barron, was published in ChemComm. In this viewpoint we analyze this pioneering work and we used it as a starting point to highlight, after 20 years since its publication, the most outstanding contributions in the application of the Raman Optical Activity to proteins and biological systems.
authors.affiliation: Departamento de Química Física, Universidad de Málaga, 29071 Málaga, Spain. teodomiro@uma.es.
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Ramírez
authors.forename: Belén
authors.initials: B
authors.lastname: Nieto-Ortega
authors.forename: Juan
authors.initials: J
authors.lastname: Casado
authors.forename: Juan T
authors.initials: JT
authors.lastname: López Navarrete
mesh_terms: D049673:History, 20th Century; D009113:Muramidase / Q000737:chemistry; D009904:Optical Rotation; D011506:Proteins / Q000737:chemistry*; D013059:Spectrum Analysis, Raman / Q000266:history*; D013237:Stereoisomerism
chemical_list: D011506:Proteins; D009113:Muramidase