title: Infrahepatic inferior vena cava agenesis with bilateral renal vein thrombosis.
abstract: Congenital anomalies of the inferior vena cava (IVC) are rare and are estimated to be present in 0.07-8.7% of the general population. IVC agenesis (IVCA) is found in approximately 5% of cases of unprovoked lower extremity deep vein thrombosis in patients <30 years of age. Renal vein thrombosis (RVT) is an extremely rare and unusual presentation of IVCA. We report a unique case of a 23-year-old previously healthy man presenting with infrahepatic IVCA-induced bilateral RVT with azygos and hemiazygos continuation. To our knowledge, this is the third reported case in the literature of IVCA-induced RVT and the first to affect the bilateral renal veins in the absence of any other thrombogenic risk factors or any lower extremity venous complications. We also present a literature review of IVCA-induced vein thrombosis and highlight the lack of literature to manage this condition.
authors.affiliation: Abbott Northwestern Hospital, Minneapolis Heart Institute, Minneapolis, MN 55407, USA. Nedaa.Skeik@allina.com
authors.forename: Nedaa
authors.initials: N
authors.lastname: Skeik
authors.forename: Kelly K
authors.initials: KK
authors.lastname: Wickstrom
authors.forename: Clark W
authors.initials: CW
authors.lastname: Schumacher
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Sullivan
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D001401:Azygos Vein / Q000002:abnormalities; D006801:Humans; D008297:Male; D010690:Phlebography / Q000379:methods; D012082:Renal Veins; D012307:Risk Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D054079:Vascular Malformations / Q000150:complications* / Q000175:diagnosis; D014682:Vena Cava, Inferior / Q000002:abnormalities*; D020246:Venous Thrombosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D055815:Young Adult
chemical_list: D000925:Anticoagulants