title: Control of vertebrate development by MYC.
abstract: The study of MYC has led to pivotal discoveries in cancer biology, induced pluripotency, and transcriptional regulation. In this review, continuing advances in our understanding of the function of MYC as a transcription factor and how its transcriptional activity controls normal vertebrate development and contributes to developmental disorders is discussed.
authors.affiliation: Shriners Hospitals for Children Portland, Portland, Oregon 97239.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Hurlin
mesh_terms: D000818:Animals; D050976:Basic-Leucine Zipper Transcription Factors / Q000502:physiology; D019070:Cell Lineage / Q000235:genetics; D049109:Cell Proliferation; D000013:Congenital Abnormalities / Q000235:genetics; D047108:Embryonic Development / Q000235:genetics; D016259:Genes, myc / Q000502:physiology*; D014158:Transcription, Genetic / Q000502:physiology; D015533:Transcriptional Activation / Q000502:physiology; D014714:Vertebrates / Q000254:growth & development*
chemical_list: D050976:Basic-Leucine Zipper Transcription Factors; C067850:Myc associated factor X