title: A case of disseminated cryptococcosis with skin manifestations in a patient with newly diagnosed HIV.
abstract: In this case report, we provide a concise review of the pathogenesis, clinical presentation, key diagnostic findings, and treatment options for Cryptococcus. Cryptococcus neoformans is a ubiquitous dimorphic fungus that can potentially be life threatening, especially in immunocompromised hosts. It commonly infects the respiratory tract or central nervous system. However, skin manifestations can be a marker of severe and disseminated disease, particularly in individuals at higher risk, including those patients with AIDS, cancer, long-term corticosteroid use, and organ transplant recipients. A timely diagnostic workup, including skin biopsy,blood cultures, and lumber puncture, is crucial since skin lesions may mimic other infectious processes. In addition, prompt, appropriate antifungal treatment should be initiatedto decrease morbidity and mortality.
authors.affiliation: Louisiana State University Health Sciences Center, New Orleans, USA.
authors.forename: Annette
authors.initials: A
authors.lastname: Zacharia
authors.forename: Muhammad F
authors.initials: MF
authors.lastname: Khan
authors.forename: Anne E
authors.initials: AE
authors.lastname: Hull
authors.forename: Appalanaidu
authors.initials: A
authors.lastname: Sasapu
authors.forename: Michael A
authors.initials: MA
authors.lastname: Leroy
authors.forename: Joanne T
authors.initials: JT
authors.lastname: Maffei
authors.forename: Akram
authors.initials: A
authors.lastname: Shakashiro
authors.forename: Fred A
authors.initials: FA
authors.lastname: Lopez
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D003453:Cryptococcosis / Q000175:diagnosis* / Q000188:drug therapy; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000935:Antifungal Agents