title: Childhood Obesity Prevention and Treatment Research (COPTR): interventions addressing multiple influences in childhood and adolescent obesity.
abstract: This paper is the first of five papers in this issue that describes a new research consortium funded by the National Institutes of Health. It describes the design characteristics of the Childhood Obesity Prevention and Treatment Research (COPTR) trials and common measurements across the trials. The COPTR Consortium is conducting interventions to prevent obesity in pre-schoolers and treat overweight or obese 7-13 year olds. Four randomized controlled trials will enroll a total of 1700 children and adolescents (~50% female, 70% minorities), and will test innovative multi-level and multi-component interventions in multiple settings involving primary care physicians, parks and recreational centers, family advocates, and schools. For all the studies, the primary outcome measure is body mass index; secondary outcomes, moderators and mediators of intervention include diet, physical activity, home and neighborhood influences, and psychosocial factors. COPTR is being conducted collaboratively among four participating field centers, a coordinating center, and NIH project offices. Outcomes from COPTR have the potential to enhance our knowledge of interventions to prevent and treat childhood obesity.
authors.affiliation: National Institutes of Health, United States. Electronic address: prattc@nhlbi.nih.gov.
authors.forename: Charlotte A
authors.initials: CA
authors.lastname: Pratt
authors.forename: Josephine
authors.initials: J
authors.lastname: Boyington
authors.forename: Layla
authors.initials: L
authors.lastname: Esposito
authors.forename: Victoria L
authors.initials: VL
authors.lastname: Pemberton
authors.forename: Denise
authors.initials: D
authors.lastname: Bonds
authors.forename: Melinda
authors.initials: M
authors.lastname: Kelley
authors.forename: Song
authors.initials: S
authors.lastname: Yang
authors.forename: David
authors.initials: D
authors.lastname: Murray
authors.forename: June
authors.initials: J
authors.lastname: Stevens
mesh_terms: D000293:Adolescent; D002648:Child; D002985:Clinical Protocols; D003299:Cooperative Behavior; D005260:Female; D006801:Humans; D008297:Male; D063766:Pediatric Obesity / Q000209:etiology / Q000517:prevention & control* / Q000628:therapy; D016896:Treatment Outcome
keywords: Childhood obesity; Multi-site trial; Prevention; Research consortium; Treatment