title: Coblation for metastatic vertebral disease.
abstract: OBJECTIVE
  Plasma-mediated radiofrequency ablation (coblation) creates a cavity for directed polymethylmethacrylate deposition through molecular dissociation, providing a safe and efficacious cementoplasty for patients with high-risk, painful vertebral body metastatic disease. The purpose of this study was to retrospectively review and report details regarding the feasibility, safety, and efficacy of coblation and cementoplasty for treating painful advanced vertebral body metastatic disease.
  
  
  METHODS
  Fifteen patients with painful metastatic vertebral body fractures with a posterior cortical defect and/or epidural tumor extension underwent percutaneous coblation and cementoplasty. Each patient's medical record was reviewed for technical success, imaging outcome, complications, and palliative effect.
  
  
  RESULTS
  Of the 15 cases, 14 were completed successfully. Postprocedure imaging studies demonstrated adequate cement deposition within the targeted vertebral body without cement extravasation or fracture progression during the 1-3 months follow-up period. Pain relief was achieved in all patients, and no neurological damage was reported (mean follow-up, 141.1 ± 132.5 days).
  
  
  CONCLUSIONS
  Percutaneous image-guided coblation-mediated cavity creation prior to vertebroplasty allows for safe, efficacious cement deposition in patients with metastatic foci. Future studies prospectively comparing this procedure with other standard-of-care regimens are warranted.
authors.affiliation: From the Department of Radiology (J.D.P.  jdprologo@hotmail.com, J.B., K.M., I.P.), University Hospitals of Cleveland, Cleveland, Ohio, USA; The University of Toledo College of Medicine (E.L.), Toledo, Ohio, USA; the Division of Vascular and Interventional Radiology (J.D.P.), Urological Institute, Anesthesia Pain Management, and the National Center for Regenerative Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA.
authors.forename: John David
authors.initials: JD
authors.lastname: Prologo
authors.forename: Ji
authors.initials: J
authors.lastname: Buethe
authors.forename: Kelly
authors.initials: K
authors.lastname: Mortell
authors.forename: Eric
authors.initials: E
authors.lastname: Lee
authors.forename: Indravadan
authors.initials: I
authors.lastname: Patel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017115:Catheter Ablation / Q000379:methods*; D060826:Cementoplasty; D005240:Feasibility Studies; D005260:Female; D005471:Fluoroscopy; D050815:Fractures, Compression / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology / Q000601:surgery; D015641:Radiography, Interventional; D012189:Retrospective Studies; D016103:Spinal Fractures / Q000209:etiology / Q000601:surgery*; D013125:Spinal Neoplasms / Q000150:complications / Q000556:secondary* / Q000601:surgery