title: [New application of phosphodiesterase-5 inhibitors in uro-andrology].
abstract: Phosphodiesterase type 5 (PDE5) inhibitors are the most classic first-line medicine for male erectile dysfunction. Recent researches have demonstrated that PDE5 inhibitors can also be employed in the treatment of lower urinary tract symptoms, renal ischemia/reperfusion injury and testicular torsion. This article updates the application of PDE5 inhibitors in these fields and their relevant mechanisms.
authors.affiliation: Department of Urology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Human Sperm Bank, Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China. Lizhengboshi@163.com
authors.forename: Zheng
authors.initials: Z
authors.lastname: Li
authors.forename: Hui
authors.initials: H
authors.lastname: Lu
mesh_terms: D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000188:drug therapy*; D008297:Male; D058986:Phosphodiesterase 5 Inhibitors / Q000627:therapeutic use*; D015427:Reperfusion Injury / Q000188:drug therapy*; D013086:Spermatic Cord Torsion / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D058986:Phosphodiesterase 5 Inhibitors