title: Association between non-alcoholic fatty liver disease, insulin resistance and Helicobacter pylori.
abstract: Here we report a case of a 55-year Caucasian man, who improved the metabolic profile after the treatment for Helicobacter pylori eradication. In particular, we report the changes in homeostatic model assessment of insulin resistance, fatty liver index and echographic liver pattern. We hypothesize the co-factorial role of H. pylori in the mechanisms involved in non-alcoholic fatty liver disease pathogenesis and insulin resistance, by the cytokine serum changes. If this correlation is confirmed, the H. pylori treatment may represent an option in the clinical management of liver steatosis.
authors.affiliation: Department of Health Sciences, University "Magna Græcia", Viale Europa - Germaneto, 88100 Catanzaro, Italy. Electronic address: l.abenavoli@unicz.it.
authors.forename: Ludovico
authors.initials: L
authors.lastname: Abenavoli
authors.forename: Natasa
authors.initials: N
authors.lastname: Milic
authors.forename: Mario
authors.initials: M
authors.lastname: Masarone
authors.forename: Marcello
authors.initials: M
authors.lastname: Persico
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000658:Amoxicillin; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001786:Blood Glucose; D017291:Clarithromycin; D016207:Cytokines / Q000097:blood; D005234:Fatty Liver / Q000188:drug therapy*; D016481:Helicobacter Infections / Q000188:drug therapy*; D016480:Helicobacter pylori; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance / Q000502:physiology*; D007558:Italy; D008297:Male; D055442:Metabolome / Q000187:drug effects*; D008875:Middle Aged; D065626:Non-alcoholic Fatty Liver Disease
chemical_list: D000900:Anti-Bacterial Agents; D001786:Blood Glucose; D016207:Cytokines; D007328:Insulin; D000658:Amoxicillin; D000410:Alanine Transaminase; D017291:Clarithromycin