title: Severe allergic dermatitis after closure of foramen ovale with Amplatzer occluder.
abstract: Allergic reaction to nitinol is rarely reported, and its incidence, symptoms, and course have not been clearly defined. We report an occurrence of severe progressive generalized exanthema 3 days after the implantation of an Amplatzer occluder for a patent foramen ovale, with symptoms disappearing immediately after surgical removal of the device 3 months later. The risks and possible prevention of allergic reaction to nickel and especially to titanium are discussed.
authors.affiliation: 2nd Department of Medicine-Cardiovascular Medicine, 1st Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic. jan.belohlavek@vfn.cz
authors.forename: Jan
authors.initials: J
authors.lastname: Belohlavek
authors.forename: Simona
authors.initials: S
authors.lastname: Belohlavkova
authors.forename: Jaroslav
authors.initials: J
authors.lastname: Hlubocky
authors.forename: Vratislav
authors.initials: V
authors.lastname: Mrazek
authors.forename: Ales
authors.initials: A
authors.lastname: Linhart
authors.forename: Stepan
authors.initials: S
authors.lastname: Podzimek
mesh_terms: D000328:Adult; D000497:Alloys / Q000009:adverse effects*; D006328:Cardiac Catheterization / Q000379:methods; D017449:Dermatitis, Allergic Contact / Q000209:etiology* / Q000503:physiopathology; D020878:Device Removal / Q000379:methods*; D004868:Equipment Failure; D005260:Female; D005500:Follow-Up Studies; D054092:Foramen Ovale, Patent / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D035583:Rare Diseases; D055989:Septal Occluder Device / Q000009:adverse effects*; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D000497:Alloys; C013616:nitinol
keywords: 21