title: [Epidemic process and vaccine prophylaxis of pertussis].
abstract: Analysis of data on epidemic process of pertussis infection in conditions of wide coverage of population by prophylactic vaccination is presented. Post-vaccination immunity against pertussis was shown to reduce with age; therefore a large part of vaccinated children becomes susceptible to this infection already in primary school age. Epidemic process of pertussis continues both as manifest form and as subclinical and atypical forms. The main reservoir of pertussis infection is older age population groups. The necessity to implement programs of revaccination against pertussis in older children, adolescents and adults is justified, Characteristics of vaccines for immune prophylaxis of pertussis infection are given.
authors.forename: E M
authors.initials: EM
authors.lastname: Zaĭtsev
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines / Q000008:administration & dosage / Q000276:immunology*; D058872:Epidemics / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007117:Immunization, Secondary; D007223:Infant; D012426:Russia / Q000453:epidemiology; D014613:Vaccines, Attenuated; D022223:Vaccines, Subunit; D014917:Whooping Cough / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*
chemical_list: D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines; D014613:Vaccines, Attenuated; D022223:Vaccines, Subunit