title: Outbreak of extensively drug-resistant Acinetobacter baumannii indigo-pigmented strains.
abstract: Acinetobacter baumannii pigmented strains are not common in clinical settings. Here, we report an outbreak caused by indigo-pigmented A. baumannii strains isolated in an acute care hospital in Argentina from March to September 2012. Pan-PCR assays exposed a unique pattern belonging to the recently described regional CC113(B)/CC79(P) clonal complex that confirms the relevant relationships among the indigo-pigmented A. baumannii strains. All of them were extensively drug resistant and harbored different genetic elements associated with horizontal genetic transfer, such as the transposon Tn2006, class 2 integrons, AbaR-type islands, IS125, IS26, strA, strB, florR, and the small recombinase ISCR2 associated with the sul2 gene preceded by ISAba1.
authors.affiliation: Instituto de Microbiología y Parasitología Médica (IMPaM, UBA-CONICET), Facultad de Medicina, Universidad de Buenos Aires.
authors.forename: Elisabet
authors.initials: E
authors.lastname: Vilacoba
authors.forename: Marisa
authors.initials: M
authors.lastname: Almuzara
authors.forename: Lucia
authors.initials: L
authors.lastname: Gulone
authors.forename: Rocio
authors.initials: R
authors.lastname: Rodriguez
authors.forename: Elida
authors.initials: E
authors.lastname: Pallone
authors.forename: Romina
authors.initials: R
authors.lastname: Bakai
authors.forename: Daniela
authors.initials: D
authors.lastname: Centrón
authors.forename: María Soledad
authors.initials: MS
authors.lastname: Ramírez
mesh_terms: D000151:Acinetobacter Infections / Q000453:epidemiology* / Q000382:microbiology*; D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000302:isolation & purification / Q000378:metabolism*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001118:Argentina; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004196:Disease Outbreaks; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D005838:Genotype; D006801:Humans; D020071:Interspersed Repetitive Sequences; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D058889:Molecular Typing; D010860:Pigments, Biological / Q000378:metabolism*; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial; D010860:Pigments, Biological