title: Risk factors and predictive factors for anastomotic leakage after resection for colorectal cancer: reappraisal of the literature.
abstract: Anastomotic leakage is a serious complication that can occur after colorectal surgery. Several risk factors for anastomotic leakage have been reported based on the findings of prospective and retrospective studies, including patient characteristics, the use of neoadjuvant therapy, the tumor location, intraoperative events, etc. However, as these risk factors affect each other, the statistical results have differed in each study. In addition, differences in surgical methods, including laparoscopy versus laparotomy or stapling anastomosis versus handsewn anastomosis, may influence the incidence of anastomotic leakage. This mini-review summarizes the results of reported papers to clarify the current evidence of risk factors for anastomotic leakage.
authors.affiliation: Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, Nagasaki, 852-8501, Japan, ffujita-ngs@umin.ac.jp.
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Fujita
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Torashima
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Kuroki
authors.forename: Susumu
authors.initials: S
authors.lastname: Eguchi
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D057868:Anastomotic Leak / Q000453:epidemiology / Q000209:etiology*; D059186:Chemoradiotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000601:surgery*; D013505:Digestive System Surgical Procedures / Q000379:methods; D005260:Female; D005544:Forecasting; D006801:Humans; D015994:Incidence; D010535:Laparoscopy; D007813:Laparotomy; D008297:Male; D020360:Neoadjuvant Therapy; D012307:Risk Factors; D017792:Surgical Stapling; D013536:Suture Techniques