title: A highly sensitive near-infrared fluorescent probe for cysteine and homocysteine in living cells.
abstract: A near-infrared fluorescent probe (Cy-O-CHO) for the detection of endogenous Cys/Hcy in living cells was designed and synthesized. Cy-O-CHO exhibited high sensitivity and good selectivity to Cys/Hcy under physiological conditions with a detection limit of 7.9 nM for Cys.
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Ministry of Education, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P.R. China. tangb@sdnu.edu.cn.
authors.forename: Fanpeng
authors.initials: F
authors.lastname: Kong
authors.forename: Renpu
authors.initials: R
authors.lastname: Liu
authors.forename: Ranran
authors.initials: R
authors.lastname: Chu
authors.forename: Xu
authors.initials: X
authors.lastname: Wang
authors.forename: Kehua
authors.initials: K
authors.lastname: Xu
authors.forename: Bo
authors.initials: B
authors.lastname: Tang
mesh_terms: D052160:Benzothiazoles / Q000737:chemistry; D002232:Carbocyanines / Q000737:chemistry; D003500:Cyclization; D003545:Cysteine / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D005978:Glutathione / Q000737:chemistry; D056945:Hep G2 Cells; D006710:Homocysteine / Q000032:analysis*; D006801:Humans; D019265:Spectroscopy, Near-Infrared
chemical_list: D052160:Benzothiazoles; D002232:Carbocyanines; D005456:Fluorescent Dyes; D006710:Homocysteine; C011204:cyanine dye 7; D005978:Glutathione; D003545:Cysteine