title: Disseminated nocardiosis mimicking exacerbation of pulmonary sarcoidosis.
abstract: Nocardiosis is a rare, mixed suppurative and granulomatous, bacterial infection that can affect various organs, but most commonly lungs. Clinical manifestation is usually uncharacteristic; can mimic fungal, parasitic and mycobacterial infections or malignancy. Presentation can be also similar to that of the other granulomatous diseases, among them sarcoidosis. We present an unusual case of disseminated nocardiosis in a patient diagnosed before with sarcoidosis and treated with glucocorticoids. Clinical symptoms initially mimicked exacerbation of pulmonary sarcoidosis. The course of disease was severe.
authors.affiliation: Division of Allergy and Immunology, 2nd Department of Medicine, Jagiellonian University Medical College, Cracow, Poland. j.zuk@uj.edu.pl
authors.forename: J
authors.initials: J
authors.lastname: Zuk
authors.forename: S
authors.initials: S
authors.lastname: Bazan-Socha
authors.forename: J
authors.initials: J
authors.lastname: Zarychta
authors.forename: A
authors.initials: A
authors.lastname: Leclercq
authors.forename: Marc
authors.initials: M
authors.lastname: Lecuit
authors.forename: A
authors.initials: A
authors.lastname: Le Flèche-Matéos
authors.forename: J
authors.initials: J
authors.lastname: Orłowska-Heitzman
authors.forename: J
authors.initials: J
authors.lastname: Musiał
mesh_terms: D000038:Abscess / Q000000981:diagnostic imaging / Q000453:epidemiology; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D018450:Disease Progression; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008477:Mediastinal Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology; D008775:Methylprednisolone / Q000008:administration & dosage; D009617:Nocardia Infections / Q000175:diagnosis* / Q000453:epidemiology* / Q000473:pathology; D009894:Opportunistic Infections; D017565:Sarcoidosis, Pulmonary / Q000453:epidemiology* / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D005938:Glucocorticoids; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D008775:Methylprednisolone