title: Brugada ECG disclosed by acute malaria: is it all about fever and propofol?
abstract: Brugada syndrome is an electrical cardiac disease predisposing to ventricular arrhythmias in which typical electrocardiographic (ECG) features consist of nonischemic repolarization abnormalities in the right precordial leads V1-V3. The appearance of a Brugada-ECG pattern is increasingly observed in critically ill patients and is traditionally attributed to the effect of body temperature and/or drug modulation on cardiac ion channels ("acquired Brugada syndrome"). A patient with complicated malaria in whom Brugada-ECG abnormalities appeared in concomitance with fever and propofol administration is presented. The repolarization changes did not disappear until the patient's clinical course improved.
authors.affiliation: Division of Anesthesiology and Intensive Care, University Hospital of Padova, 31100 Padua, Italy. Electronic address: meggiomarco@libero.it.
authors.forename: Marco
authors.initials: M
authors.lastname: Meggiolaro
authors.forename: Alessandro
authors.initials: A
authors.lastname: Zorzi
authors.forename: Mohamed
authors.initials: M
authors.lastname: El Maghawry
authors.forename: Francesco
authors.initials: F
authors.lastname: Peruzza
authors.forename: Federico
authors.initials: F
authors.lastname: Migliore
authors.forename: Giovanni Maria
authors.initials: GM
authors.lastname: Pittoni
mesh_terms: D053840:Brugada Syndrome / Q000209:etiology*; D004562:Electrocardiography; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects*; D008288:Malaria / Q000150:complications*; D016779:Malaria, Cerebral / Q000150:complications*; D008297:Male; D015742:Propofol / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D006993:Hypnotics and Sedatives; D015742:Propofol
keywords: Anesthesia: cardiac; Brugada syndrome; Electrocardiographic abnormality; Malaria