title: Bioactive compounds from marine mussels and their effects on human health.
abstract: The consumption of marine mussels as popular seafood has increased steadily over the past decades. Awareness of mussel derived molecules, that promote health, has contributed to extensive research efforts in that field. This review highlights the bioactive potential of mussel components from species of the genus Mytilus (e.g. M. edulis) and Perna (e.g. P. canaliculus). In particular, the bioactivity related to three major chemical classes of mussel primary metabolites, i.e. proteins, lipids, and carbohydrates, is evaluated. Within the group of proteins the focus is mainly on mussel peptides e.g. those obtained by bio-transformation processes, such as fermentation. In addition, mussel lipids, comprising polyunsaturated fatty acids (PUFAs), are discussed as compounds that are well known for prevention and treatment of rheumatoid arthritis (RA). Within the third group of carbohydrates, mussel polysaccharides are investigated. Furthermore, the importance of monitoring the mussel as food material in respect to contaminations with natural toxins produced by microalgae is discussed.
authors.affiliation: School of Chemistry, National University of Ireland, Galway (NUIG), University Road, Galway, Ireland.
authors.forename: Ulrike
authors.initials: U
authors.lastname: Grienke
authors.forename: Joe
authors.initials: J
authors.lastname: Silke
authors.forename: Deniz
authors.initials: D
authors.lastname: Tasdemir
mesh_terms: D000818:Animals; D049872:Bivalvia / Q000737:chemistry* / Q000145:classification; D058870:Food, Organic / Q000032:analysis*; D006801:Humans; D008055:Lipids / Q000032:analysis / Q000191:economics; D008387:Marine Toxins / Q000032:analysis; D011134:Polysaccharides / Q000032:analysis; D011506:Proteins / Q000032:analysis; D012758:Shellfish / Q000032:analysis* / Q000145:classification
chemical_list: D008055:Lipids; D008387:Marine Toxins; D011134:Polysaccharides; D011506:Proteins
keywords: AA; AMP; ASP; AZP; Antimicrobial peptide; Bioactivity; CFP; COX; DHA; DSP; EPA; HAB; LO; Lyprinol®; Marine biotoxins; Mollusc; Mussel; Mytilus; NSP; PSP; PUFA; Perna; amino acid; amnesic shellfish poisoning; antimicrobial peptide; azaspiracid shellfish poisoning; ciguatera fish poisoning; cyclooxigenase; diarrhetic shellfish poisoning; docosapentaenoic acid; eicosapentaenoic acid; harmful algal bloom; lipoxygenase; neurotoxic shellfish poisoning; paralytic shellfish poisoning; polyunsaturated fatty acid