title: Chiral tertiary amine thiourea-catalyzed asymmetric inverse-electron-demand Diels-Alder reaction of chromone heterodienes using 3-vinylindoles as dienophiles.
abstract: A straightforward and efficient protocol for the construction of structurally and biologically interesting chiral flavanoids incorporating three privileged structures, i.e., chromanone, dihydropyran, and indole, has been developed on the basis of chiral bifunctional tertiary amine thiourea-catalyzed asymmetric inverse-electron-demand Diels-Alder reaction of chromone heterodienes and 3-vinylindoles, which were used as dienophiles.
authors.affiliation: State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210093, People's Republic of China.
authors.forename: Zhijie
authors.initials: Z
authors.lastname: Mao
authors.forename: Aijun
authors.initials: A
authors.lastname: Lin
authors.forename: Yan
authors.initials: Y
authors.lastname: Shi
authors.forename: Haibin
authors.initials: H
authors.lastname: Mao
authors.forename: Weipeng
authors.initials: W
authors.lastname: Li
authors.forename: Yixiang
authors.initials: Y
authors.lastname: Cheng
authors.forename: Chengjian
authors.initials: C
authors.lastname: Zhu
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D002867:Chromones / Q000737:chemistry*; D061565:Cycloaddition Reaction; D004583:Electrons; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D000588:Amines; D002867:Chromones; D007211:Indoles; D014753:Vinyl Compounds; C030374:indole