title: Pancreatic cancer mortality in Serbia from 1991-2010 - a joinpoint analysis.
abstract: OBJECTIVE
  To analyze the trends of pancreatic cancer mortality in Serbia.
  
  
  METHODS
  The study covered the population of Serbia in the period 1991 to 2010. Mortality trends were assessed by the joinpoint regression analysis by age and sex.
  
  
  RESULTS
  Age-standardized mortality rates ranged from 5.93 to 8.57 per 100 000 in men and from 3.51 to 5.79 per 100 000 in women. Pancreatic cancer mortality in all age groups was higher among men than among women. It was continuously increasing since 1991 by 1.6% (95% confidence interval [CI] 1.1 to 2.0) yearly in men and by 2.2% (95% CI 1.7 to 2.7) yearly in women. Changes in mortality were not significant in younger age groups for both sexes. In older men (≥55 years), mortality was increasing, although in age groups 70-74 and 80-84 the increase was not significant. In 65-69 years old men, the increase in mortality was significant only in the period 2004 to 2010. In ≥50 years old women, mortality significantly increased from 1991 onward. In 75-79 years old women, a non-significant decrease in the period 1991 to 2000 was followed by a significant increase from 2000 to 2010.
  
  
  CONCLUSIONS
  Serbia is one of the countries with the highest pancreatic cancer mortality in the world, with increasing mortality trend in both sexes and in most age groups.
authors.affiliation: Ilic Milena, MD, PhD, Faculty of Medical Sciences, University of Kragujevac, S. Markovica 69, 34000 Kragujevac, Republic of Serbia, drmilenailic@yahoo.com.
authors.forename: Milena
authors.initials: M
authors.lastname: Ilić
authors.forename: Hristina
authors.initials: H
authors.lastname: Vlajinac
authors.forename: Jelena
authors.initials: J
authors.lastname: Marinković
authors.forename: Nikola
authors.initials: N
authors.lastname: Kocev
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000401:mortality*; D012044:Regression Analysis; D055771:Serbia / Q000453:epidemiology; D017678:Sex Distribution