title: Characteristics and provision of care in patients with chronic hand eczema: updated data from the CARPE registry.
abstract: The aim of the CARPE registry is to investigate characteristics and medical care in patients affected by chronic hand eczema. Patients are assessed by dermatological examination and patient questionnaire. Socio-economic and clinical data are collected, and quality of life is measured using the Dermatology Life Quality Index (DLQI). A total of 1,163 patients with chronic hand eczema were eligible for analysis (mean age 47.0 years; 54.6% female; mean disease duration 7.6 years). At inclusion, chronic hand eczema was very severe in 23.4%, severe in 47.0%, moderate in 20.1%, and clear or almost clear in 9.6% of patients. Median DLQI was 8.0. In all, 93.8% of patients reported use of topical corticosteroids, 25.6% systemic antihistamines, 28.3% topical calcineurin-inhibitors, 38.0% ultraviolet phototherapy, and 35.3% systemic treatment (19.7% alitretinoin) prior to inclusion in the registry. A significant proportion of patients may not receive adequate treatment according to the guideline on management of hand eczema.
authors.affiliation: Medical Sociology, Department of Epidemiology and Preventive Medicine, University of Regensburg, DE-93053 Regensburg, Germany. Christian.Apfelbacher@klinik.uni-regensburg.de.
authors.forename: Christian
authors.initials: C
authors.lastname: Apfelbacher
authors.forename: Sonja
authors.initials: S
authors.lastname: Molin
authors.forename: Elke
authors.initials: E
authors.lastname: Weisshaar
authors.forename: Andrea
authors.initials: A
authors.lastname: Bauer
authors.forename: Peter
authors.initials: P
authors.lastname: Elsner
authors.forename: Vera
authors.initials: V
authors.lastname: Mahler
authors.forename: Melanie
authors.initials: M
authors.lastname: Weiss
authors.forename: Thomas
authors.initials: T
authors.lastname: Ruzicka
authors.forename: Thomas L
authors.initials: TL
authors.lastname: Diepgen
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000077556:Alitretinoin; D065095:Calcineurin Inhibitors; D002908:Chronic Disease; D004485:Eczema / Q000150:complications* / Q000628:therapy*; D005260:Female; D005858:Germany; D005938:Glucocorticoids / Q000627:therapeutic use; D006229:Hand Dermatoses / Q000150:complications* / Q000628:therapy*; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009790:Occupations / Q000706:statistics & numerical data; D011537:Pruritus / Q000209:etiology; D011788:Quality of Life; D012042:Registries; D012720:Severity of Illness Index; D014212:Tretinoin / Q000627:therapeutic use; D014467:Ultraviolet Therapy; D055815:Young Adult
chemical_list: D065095:Calcineurin Inhibitors; D005938:Glucocorticoids; D006633:Histamine Antagonists; D000077556:Alitretinoin; D014212:Tretinoin