title: Hair follicle signaling networks: a dermal papilla-centric approach.
abstract: Functional testing of dermal papilla (DP) signaling inputs into hair follicle (HF) morphogenesis and regeneration is becoming possible with the advent of new Cre lines. Targeted deletion of the signature genes in early DP precursors has revealed significant signaling redundancy during HF morphogenesis. Furthermore, the DP lineage commitment program can be exploited for generating highly inductive DP cells to be used in HF bioengineering assays.
authors.affiliation: Department of Developmental and Cell Biology, Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, California, USA.
authors.forename: Raul
authors.initials: R
authors.lastname: Ramos
authors.affiliation: Department of Developmental and Cell Biology, Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, California, USA.
authors.forename: Christian F
authors.initials: CF
authors.lastname: Guerrero-Juarez
authors.affiliation: Department of Developmental and Cell Biology, Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, California, USA. Electronic address: plikus@uci.edu.
authors.forename: Maksim V
authors.initials: MV
authors.lastname: Plikus
mesh_terms: D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000378:metabolism*; D020405:Dermis / Q000196:embryology*; D005260:Female; D006197:Hair / Q000254:growth & development*; D018859:Hair Follicle / Q000196:embryology* / Q000378:metabolism*; D008049:Lipase / Q000235:genetics*; D008297:Male; D009024:Morphogenesis / Q000502:physiology*; D010727:Phosphoric Diester Hydrolases / Q000235:genetics*; D011247:Pregnancy; D055748:SOXB1 Transcription Factors / Q000378:metabolism*; D000099189:Lysophospholipase D
chemical_list: D019485:Bone Morphogenetic Proteins; D008049:Lipase; D010727:Phosphoric Diester Hydrolases; D055748:SOXB1 Transcription Factors; D000099189:Lysophospholipase D; C584508:lipase H, mouse
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