title: Authors' reply to the letter to the editor by Olivier J.M. Guilbaud.
authors.affiliation: Novartis Pharmaceuticals Corp., One Health Plaza, East Hanover, NJ, USA.
authors.forename: Cheng
authors.initials: C
authors.lastname: Zheng
authors.forename: Jixian
authors.initials: J
authors.lastname: Wang
authors.forename: Lihui
authors.initials: L
authors.lastname: Zhao
mesh_terms: D018849:Controlled Clinical Trials as Topic / Q000379:methods*; D015195:Drug Design; D006801:Humans; D012107:Research Design