title: Programmable hydrogels for the controlled release of therapeutic nucleic acid aptamers via reversible DNA hybridization.
abstract: Reversible DNA hybridization can be used as a new mechanism to control the sustained and triggered release of therapeutic oligonucleotides from hydrogels.
authors.affiliation: Department of Bioengineering, College of Engineering, The Pennsylvania State University, University Park, PA 16802-6804, USA. yxwbio@engr.psu.edu.
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Zhang
authors.forename: Mark R
authors.initials: MR
authors.lastname: Battig
authors.forename: Yong
authors.initials: Y
authors.lastname: Wang
mesh_terms: D052157:Aptamers, Nucleotide / Q000008:administration & dosage* / Q000737:chemistry; D004247:DNA / Q000737:chemistry; D003692:Delayed-Action Preparations / Q000737:chemistry*; D020100:Hydrogels / Q000737:chemistry*; D009693:Nucleic Acid Hybridization
chemical_list: D052157:Aptamers, Nucleotide; D003692:Delayed-Action Preparations; D020100:Hydrogels; D004247:DNA