title: Lower fat and better quality diet therapy for children with pharmacoresistant epilepsy.
abstract: The ketogenic diet (KD) is an established, effective, nonpharmacologic treatment for children with pharmacoresistant epilepsy. Although the KD is the most well-established dietary therapy for epilepsy, it is too restrictive and is associated with serious complications; therefore, alternative lower-fat diets, including a modified Atkins diet and low-glycemic index diet, have been developed. Recent ongoing clinical evidence suggests that other dietary therapies have an efficacy almost comparable to that of the KD. In addition, a diet rich in polyunsaturated fatty acids appears to increase the efficacy of diet therapy and reduce the complications of a high-fat diet. Here, we review the systematic information about lower-fat diets and better-quality dietary therapies and the current clinical status of each of these dietary approaches.
authors.affiliation: Division of Pediatric Neurology, Department of Pediatrics, Pediatric Epilepsy Clinic, Epilepsy Research Institute, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jung-Rim
authors.initials: JR
authors.lastname: Yoon
authors.forename: Heung Dong
authors.initials: HD
authors.lastname: Kim
authors.forename: Hoon-Chul
authors.initials: HC
authors.lastname: Kang
keywords: Atkins diet; Epilepsy; Ketogenic diet; Low-glycemic index diet; Polyunsaturated fatty acid
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