title: Image-guided percutaneous lipiodol-pingyangmycin suspension injection therapy for sacral chordoma.
abstract: A 74-year-old man presented with a progressively worsening pain in sacrum and was diagnosed to have a sacral chordoma by biopsy in May, 2004. Percutaneous intratumoral injection with lipiodol-pingyangmycin suspension (LPS) was carried out under image guidance and repeated when the pain in sacrum recurred and the tumor increased. During a 6-year follow-up period, three sessions of this treatment were executed. CT imaging and Karnofsky Performance Score were used to evaluate the size of tumor and quality of life, respectively. The patient was free of pain after each procedure and had a high quality of life with a Karnofsky Performance Score above 80 points. The tumor lesion in sacral area was effectively controlled. No complications were observed. Percutaneous intratumoral injection with LPS under image guidance may be an effective and safe alternative for the patients with sacral chordoma.
authors.affiliation: Department of Interventional Radiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, P.R.China. ; Department of Medical Imaging, the 2nd Affiliated Hospital, Medical College of Shantou University, Shantou 515041, P.R.China.
authors.forename: Dexiao
authors.initials: D
authors.lastname: Huang
authors.forename: Yong
authors.initials: Y
authors.lastname: Chen
authors.forename: Qingle
authors.initials: Q
authors.lastname: Zeng
authors.forename: Renhua
authors.initials: R
authors.lastname: Wu
authors.forename: Yanhao
authors.initials: Y
authors.lastname: Li
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D001706:Biopsy; D001761:Bleomycin / Q000008:administration & dosage / Q000031:analogs & derivatives; D002817:Chordoma / Q000175:diagnosis / Q000188:drug therapy*; D004998:Ethiodized Oil / Q000008:administration & dosage; D006801:Humans; D015552:Injections, Intralesional; D008279:Magnetic Resonance Imaging; D008297:Male; D012447:Sacrum; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000188:drug therapy*; D013535:Suspensions; D014057:Tomography, X-Ray Computed
chemical_list: D013535:Suspensions; D001761:Bleomycin; C025703:bleomycetin; D004998:Ethiodized Oil
keywords: Lipiodol-pingyangmycin suspension; Percutaneous intratumoral injection; Sacral chordoma
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