title: Copper-catalyzed cyclic oxytrifluoromethylation of 2,3-allenoic acids to trifluoromethylated butenolides.
abstract: Rounding up: An efficient copper-catalyzed cyclic oxytrifluoromethylation of 2,3-allenoic acids under mild conditions, providing a straightforward approach to β-trifluoromethylated butenolides has been developed. Based on the successful trapping of a CF3 radical intermediate, a mechanism involving π-allylic copper(III) or radical intermediate is proposed.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 North Zhongshan Lu, Shanghai 200062 (P. R. China).
authors.forename: Qiong
authors.initials: Q
authors.lastname: Yu
authors.forename: Shengming
authors.initials: S
authors.lastname: Ma
keywords: allenoic acids; catalysis; copper; oxytrifluoromethylation; radicals