title: Takotsubo cardiomyopathy associated with severe hypocalcemia secondary to idiopathic hypoparathyroidism.
abstract: The etiology and pathophysiology of takotsubo cardiomyopathy have not yet been fully clarified. We report a case of takotsubo cardiomyopathy associated with severe hypocalcemia secondary to hypoparathyroidism. A 69-year-old woman presented with acute pulmonary edema caused by severe left ventricular dysfunction with apical ballooning compatible with takotsubo cardiomyopathy. Laboratory tests revealed severe hypocalcemia secondary to idiopathic hypoparathyroidism. Coronary angiography showed normal coronary artery function. Her symptoms and signs of heart failure improved dramatically with the correction of hypocalcemia through calcium and calcitriol replacement.
authors.affiliation: Department of Internal Medicine, School of Medicine, Soonchunhyang University, Cheonan Hospital, Cheonan, Korea.
authors.forename: Ho Sung
authors.initials: HS
authors.lastname: Rhee
authors.forename: Se-Whan
authors.initials: SW
authors.lastname: Lee
authors.forename: Young Kyu
authors.initials: YK
authors.lastname: Jung
authors.forename: Ung
authors.initials: U
authors.lastname: Jeon
authors.forename: Sang-Ho
authors.initials: SH
authors.lastname: Park
authors.forename: Seung-Jin
authors.initials: SJ
authors.lastname: Lee
authors.forename: Won-Yong
authors.initials: WY
authors.lastname: Sin
authors.forename: Dong-Kyu
authors.initials: DK
authors.lastname: Jin
keywords: Hypocalcemia; Hypoparathyroidism; Takotsubo cardiomyopathy
references.citation: Ann Med Interne (Paris). 2001 Nov;152(7):483-5
references.pmid: 11965090
references.citation: Am J Med. 1985 Jun;78(6 Pt 1):1033-5
references.pmid: 4014262
references.citation: N Engl J Med. 2005 Feb 10;352(6):539-48
references.pmid: 15703419
references.citation: J Clin Invest. 1981 Apr;67(4):1215-27
references.pmid: 6259214
references.citation: J Am Coll Cardiol. 2003 Mar 5;41(5):737-42
references.pmid: 12628715
references.citation: J Am Coll Cardiol. 2001 Jul;38(1):11-8
references.pmid: 11451258
references.citation: Am Heart J. 2002 Mar;143(3):448-55
references.pmid: 11868050
references.citation: Clin Cardiol. 1998 Mar;21(3):227-8
references.pmid: 9541771
references.citation: Br Heart J. 1990 Jan;63(1):58-60
references.pmid: 2310646
references.citation: Int J Cardiol. 2008 Mar 14;124(3):283-92
references.pmid: 17651841
references.citation: Chest. 1980 Oct;78(4):663-5
references.pmid: 6448134
references.citation: Int J Cardiol. 1997 Aug 29;61(1):89-91
references.pmid: 9292338
references.citation: S Afr Med J. 1988 Feb 20;73(4):242-4
references.pmid: 3340968