title: Ultrasonic enhancing amorphization during synthesis of calcium phosphate.
abstract: Amorphous calcium phosphate (ACP) has great application potential in biomaterials field due to its non-cytotoxicity, high bioactivity, good cytocompatibility, and so on. The results of this research demonstrated that ultrasonic obviously enhanced amorphization during synthesis of calcium phosphate. The ACP phase was relatively ideal when the solvent of Ca(NO3)2·4H2O was ethanol and the solvent of (NH4)2HPO4 was a mixture of water and ethanol, under ultrasonic. In-situ crystallization of ACP could be observed by HRTEM. The mechanism on the effects of ultrasonic on amorphization of the synthesized calcium phosphate was discussed. It was suggested that ultrasonic synthesis might be a facile method to prepare pure and safe ACP related biomaterials.
authors.affiliation: Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials, Ministry of Education, Shandong University, Ji'nan 250061, China; School of Materials Science and Engineering, Shandong University, Ji'nan 250061, China.
authors.forename: Kun
authors.initials: K
authors.lastname: He
authors.forename: Gui-Yong
authors.initials: GY
authors.lastname: Xiao
authors.forename: Wen-Hua
authors.initials: WH
authors.lastname: Xu
authors.forename: Rui-Fu
authors.initials: RF
authors.lastname: Zhu
authors.forename: Yu-Peng
authors.initials: YP
authors.lastname: Lu
mesh_terms: D002130:Calcium Phosphates / Q000138:chemical synthesis* / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D000431:Ethanol / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D014465:Ultrasonics; D014867:Water / Q000737:chemistry
chemical_list: D002130:Calcium Phosphates; D012997:Solvents; D014867:Water; D000431:Ethanol; C020243:calcium phosphate
keywords: Amorphous calcium phosphate (ACP); Crystallinity; Hydroxyapatite; Ultrasonic