title: The effect of xylometazoline spray for expansion of nasal cavity.
abstract: BACKGROUND
  During nasotracheal intubation it is important to have proper pretreatment for nasal mucosa constriction and nasal cavity expanding. Nasal packing of epinephrine gauze is widely used as well as xylometazoline. The aim of this study was to compare and evaluate the efficacy of prophylactic intranasal spray of xylometazoline against epinephrine gauze packing in expanding the nasal cavity.
  
  
  METHODS
  Volunteers (n = 32) in their twenties without nasal disease such as septal deviation or rhinitis were enrolled in the study. The more patent nostril in each subject was measured by acoustic rhinometry as the base value. After intranasal spray of xylometazoline, the same nostril was remeasured by same method. Twenty four hours later, intranasal packing of epinephrine gauze was done and the same treatment was done. Subject preferences about the procedures were asked.
  
  
  RESULTS
  THERE WERE SIGNIFICANT DIFFERENCE AMONG TREATMENTS (BASE VALUE: 0.582 ± 0.164 cm(2), xylometazoline spray: 0.793 ± 0.165 cm(2), epinephrine gauze packing: 0.990 ± 0.290 cm(2)) in acoustic rhinometry. While the epinephrine gauze packing showed more efficient mucosa constriction, subjects preferred xylometazoline spray.
  
  
  CONCLUSIONS
  Even though xylometazoline spray was less effective than epinephrine gauze packing, the simplicity and convenience compensated. In patients undergoing nasotracheal intubation, xylometazoline spray can be an alternative to epinephrine gauze packing.
authors.affiliation: Department of Anesthesiology and Pain Medicine, College of Medicine, Chungbuk National University, Cheongju, Korea.
authors.forename: Jun-Sung
authors.initials: JS
authors.lastname: Han
authors.forename: Sang-Hi
authors.initials: SH
authors.lastname: Park
authors.forename: Young Duck
authors.initials: YD
authors.lastname: Shin
authors.forename: Eunjung
authors.initials: E
authors.lastname: Kwon
authors.forename: Woo Sub
authors.initials: WS
authors.lastname: Shim
authors.forename: Jin Ho
authors.initials: JH
authors.lastname: Bae
keywords: Acoustic rhinometry; Epinephrine; Nasal intubation; Xylometazoline
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