title: Cell biology in neuroscience: Cellular and molecular mechanisms underlying axon formation, growth, and branching.
abstract: Proper brain wiring during development is pivotal for adult brain function. Neurons display a high degree of polarization both morphologically and functionally, and this polarization requires the segregation of mRNA, proteins, and lipids into the axonal or somatodendritic domains. Recent discoveries have provided insight into many aspects of the cell biology of axonal development including axon specification during neuronal polarization, axon growth, and terminal axon branching during synaptogenesis.
authors.affiliation: The Scripps Research Institute, Dorris Neuroscience Center, Department of Molecular and Cellular Neuroscience, La Jolla, CA 92037.
authors.forename: Tommy L
authors.initials: TL
authors.lastname: Lewis
authors.forename: Julien
authors.initials: J
authors.lastname: Courchet
authors.forename: Franck
authors.initials: F
authors.lastname: Polleux
mesh_terms: D000818:Animals; D001369:Axons / Q000502:physiology*; D002468:Cell Physiological Phenomena; D006801:Humans; D009474:Neurons / Q000166:cytology* / Q000502:physiology*; D009488:Neurosciences; D015398:Signal Transduction
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