title: A case report of melioidosis in a diabetic patient in a union territory.
abstract: Melioidosis is an emerging disease in India. Cases have also been reported from South East Asia, Australia and Japan. Major risk factors for melioidosis are diabetes mellitus, preexisting renal disease and thalassemia. Exposure to contaminated soil and water are also significant occupational hazards associated with the disease. A patient with diabetes of six years duration on regular medication presented with fever, generalised myalgia and headache for a week. Blood and bone marrow culture yielded Burkholderia pseudomallei. A Computed tomography (CT) study of the thorax also revealed multiple scattered nodules in both lungs. The patient was treated with imipenem and doxycycline. His condition improved gradually and he was advised oral sulfamethoxazole/trimethoprim and doxycycline for a period of three months and has been followed up regularly.
authors.affiliation: Department of Microbiology, Pondicherry Institute of Medical Sciences, Ganapthichettikulum, Kalapet, Puducherry - 605014.
authors.forename: Esther
authors.initials: E
authors.lastname: Paul
authors.forename: M
authors.initials: M
authors.lastname: Sudhagar
authors.forename: S
authors.initials: S
authors.lastname: Anandhalakshmi
authors.forename: Shanthi
authors.initials: S
authors.lastname: Mathias
keywords: Bone marrow culture; Burkholderia pseudomallei; Diabetes mellitus; Melioidosis
references.citation: Int J Tuberc Lung Dis. 2008 Oct;12(10):1209-15
references.pmid: 18812053
references.citation: BMC Infect Dis. 2012 Oct 04;12:242
references.pmid: 23035948
references.citation: BMC Infect Dis. 2010 Oct 21;10:302
references.pmid: 20964837
references.citation: J Assoc Physicians India. 2002 Nov;50:1438-9
references.pmid: 12583480
references.citation: J Clin Pathol. 2000 Feb;53(2):159-60
references.pmid: 10767836
references.citation: Clin Infect Dis. 1999 Aug;29(2):408-13
references.pmid: 10476750
references.citation: Clin Infect Dis. 2003 Mar 1;36(5):e71-2
references.pmid: 12594658
references.citation: Asian Pac J Trop Med. 2012 Apr;5(4):329-30
references.pmid: 22449529
references.citation: Trans R Soc Trop Med Hyg. 2002 Jan-Feb;96(1):72-6
references.pmid: 11926000
references.citation: Antimicrob Agents Chemother. 2005 Oct;49(10):4020-5
references.pmid: 16189075
references.citation: Southeast Asian J Trop Med Public Health. 2010 Mar;41(2):401-9
references.pmid: 20578524
references.citation: Rev Infect Dis. 1989 May-Jun;11(3):413-25
references.pmid: 2665001
references.citation: Clin Infect Dis. 2000 Oct;31(4):981-6
references.pmid: 11049780
references.citation: Clin Infect Dis. 2012 Feb 1;54(3):362-9
references.pmid: 22057702
references.citation: Infect Immun. 2006 Mar;74(3):1706-11
references.pmid: 16495542
references.citation: Trans R Soc Trop Med Hyg. 1990 Jul-Aug;84(4):585-7
references.pmid: 2091358
references.citation: Int J Biomed Sci. 2007 Sep;3(3):144-52
references.pmid: 23675037
references.citation: Trans R Soc Trop Med Hyg. 2000 May-Jun;94(3):301-4
references.pmid: 10975006
references.citation: Clin Microbiol Rev. 2005 Apr;18(2):383-416
references.pmid: 15831829
references.citation: Acta Trop. 2000 Feb 5;74(2-3):121-7
references.pmid: 10674639
references.citation: Curr Opin Infect Dis. 2010 Dec;23(6):554-9
references.pmid: 20847695
references.citation: Infect Immun. 1993 Oct;61(10):4045-50
references.pmid: 7691742