title: Central retinal vein occlusion following hypobaric chamber exposure.
abstract: BACKGROUND
  Mountain climbers who ascend to a high altitude could suffer high altitude retinopathy, which varies from tortuous retinal vessels and hemorrhages to retinal vascular obstruction. As hypobaric chamber training could imitate a fast ascent and could lead to decompression sickness, a simulated flight could also lead to a high altitude retinopathy.
  
  
  METHODS
  This paper will present a case of central retinal vein occlusion that occurred after exposure to a hypobaric chamber and Valsalva maneuver. Although the patient was treated with an intravitreal bevacizumab injection, his macular edema was aggravated after a helicopter flight, which involved re-exposure to high altitudes and a Valsalva maneuver.
  
  
  CONCLUSIONS
  Systemic evaluation including blood coagulation and carotid Doppler studies did not reveal any lesion. Notably, central retinal vein occlusion can occur in young, healthy individuals after hypobaric chamber exposure.
authors.affiliation: Aerospace Medical Center, Republic of Korea Air Force, Cheongwon-gun, Chungbuk, Korea.
authors.forename: Kyoung Min
authors.initials: KM
authors.lastname: Lee
authors.forename: Seok Ju
authors.initials: SJ
authors.lastname: Yoo
authors.forename: Se Joon
authors.initials: SJ
authors.lastname: Woo
mesh_terms: D000337:Aerospace Medicine; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use; D001273:Atmosphere Exposure Chambers / Q000009:adverse effects*; D000068258:Bevacizumab; D006801:Humans; D058449:Intravitreal Injections; D008269:Macular Edema / Q000188:drug therapy / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012166:Retinal Hemorrhage / Q000000981:diagnostic imaging; D012170:Retinal Vein Occlusion / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014636:Valsalva Maneuver
chemical_list: D020533:Angiogenesis Inhibitors; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab