title: Determination of the antibacterial activity of crude extracts and compounds isolated from Hortia oreadica (Rutaceae) against oral pathogens.
abstract: Extracts from Hortia oreadica afforded four dihydrocinnamic acid derivatives, isolated from the n-hexane extract, as well as limonoid guyanin and the furoquinoline alkaloid dictamnine, both isolated from the dichloromethane extract. The extracts and the isolated compounds were tested against some oral pathogens, so as to investigate their antibacterial activity. The results showed that the n-hexane extract and the compound dictamnine are the most active against the selected microorganisms.
authors.affiliation: Centro de Ciências Exatas e de Tecnologia, Departamento de Química, Universidade Federal de São Carlos , São Carlos, SP , Brasil.
authors.forename: Vanessa Gisele Pasqualotto
authors.initials: VG
authors.lastname: Severino
authors.forename: Maria Fátima das Graças Fernandes
authors.initials: MF
authors.lastname: da Silva
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Lucarini
authors.forename: Lilian Bueno
authors.initials: LB
authors.lastname: Montanari
authors.forename: Wilson Roberto
authors.initials: WR
authors.lastname: Cunha
authors.forename: Adriana Helena Chicharo
authors.initials: AH
authors.lastname: Vinholis
authors.forename: Carlos Henrique Gomes
authors.initials: CH
authors.lastname: Martins
keywords: Hortia oreadica; MIC; Rutaceae; antibacterial activity; oral pathogens
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