title: Improved stereochemical analysis of conformationally flexible diamines by binding to a bisporphyrin molecular clip.
abstract: The relative stereochemistry of acyclic diamines with several stereogenic centers has been analyzed by NMR spectroscopy in combination with conformational deconvolution. Binding to a bisporphyrin molecular clip improves the stereochemical assignment significantly. The diamines were synthesized from inexpensive sugar alcohols, and their stable hydrochlorides were quantitatively converted into free bases by treatment with ion-exchange resin.
authors.affiliation: Uppsala University, Department of Chemistry, BMC, Box 576, 751 23 Uppsala (Sweden).
authors.forename: Sara
authors.initials: S
authors.lastname: Norrehed
authors.forename: Henrik
authors.initials: H
authors.lastname: Johansson
authors.forename: Helena
authors.initials: H
authors.lastname: Grennberg
authors.forename: Adolf
authors.initials: A
authors.lastname: Gogoll
keywords: N ligands; NMR spectroscopy; configuration determination; conformation analysis; host-guest systems