title: [Anti-Hu antibody syndrome: diagnostic and therapeutic difficulties].
abstract: BACKGROUND
  Anti-Hu antibody syndrome is a paraneoplastic syndrome usually associated with small cell lung carcinoma which induces various symptoms, particularly neurological ones.
  
  
  METHODS
  We describe the case of a 49-year old woman with a small cell lung carcinoma who initially experiences a spontaneous regression but then developed neurological symptoms associated with severe autonomic dysfunction manifesting as chronic intestinal pseudo-obstruction and leading finally to hemodynamic failure.
  
  
  CONCLUSIONS
  Anti-Hu antibody syndrome remains a rare entity. Its diagnosis must be considered in the face of neurologic symptoms associated with small cell lung cancer.
authors.affiliation: Département universitaire de radiothérapie, centre Oscar-Lambret, université Lille II, 59020 Lille cedex, France.
authors.forename: T
authors.initials: T
authors.lastname: Leroy
authors.forename: H
authors.initials: H
authors.lastname: Porte
authors.forename: C
authors.initials: C
authors.lastname: Rousselot
authors.forename: S
authors.initials: S
authors.lastname: Taieb
authors.forename: O
authors.initials: O
authors.lastname: Outteryck
authors.forename: É
authors.initials: É
authors.lastname: Dansin
mesh_terms: D000974:Antibodies, Antinuclear / Q000502:physiology; D003937:Diagnosis, Differential; D051959:ELAV Proteins / Q000276:immunology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000276:immunology; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D055752:Small Cell Lung Carcinoma / Q000150:complications / Q000276:immunology; D012907:Smoking / Q000009:adverse effects
chemical_list: D000974:Antibodies, Antinuclear; D051959:ELAV Proteins
keywords: Anti-Hu antibodies; Anticorps anti-Hu; Bronchial cancer; Cancer bronchique; Cancer petites cellules; Small cell cancer