title: Effect of herbal formula xiao pi-II on functional dyspepsia.
abstract: OBJECTIVE
  To investigate the therapeutic effect of the herbal medication Xiao Pi-II on the symptoms and gastric motility of patients with functional dysepsia (FD).
  
  
  METHODS
  A total of 180 FD patients were divided randomly and equally into Xiao Pi-II and mosapride groups. The two groups were treated with Xiao Pi-II (100 mL, t.d.s., ante cibum) and mosapride (5 mg, t. d.s., ante cibum) for 2 weeks. Before treatment and 3 days after all medication was stopped, patients responded to a questionnaire evaluating gastrointestinal symptoms and were assessed with abdominal three dimensional ultrasonography (3D-US) for gastric motility.
  
  
  RESULTS
  Gastrointestinal symptoms (especially bloating, post-prandial fullness and eructation) were improved significantly in FD patients treated with Xiao Pi-II (P < 0.05, P < 0.05, and P < 0.05), but no significant difference was found in the mosapride group (P > 0.05). The effective rates in the Xiao Pi-II and mosapride group were 86.7% and 60.0%, respectively (P < 0.05). The gastric liquid emptying rate (GLER) in the Xiao Pi-II group showed a significant increase (P < 0.01) after 2 weeks of treatment but there was no significant change (P > 0.05) of GLER in the mosapride group.
  
  
  CONCLUSIONS
  Compared with mosapride, Xiao Pi-II improved symptoms and GLER significantly in FD patients with delayed gastric emptying.
authors.affiliation: Department of Gastroenterology, First Affiliated Hospital of Liaoning Medical University, Jinzhou 121001, China.
authors.forename: Baohai
authors.initials: B
authors.lastname: Liu
authors.forename: Xuehua
authors.initials: X
authors.lastname: Piao
authors.forename: Lianyi
authors.initials: L
authors.lastname: Guo
mesh_terms: D000328:Adult; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D004415:Dyspepsia / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D005746:Gastric Emptying / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D004365:Drugs, Chinese Herbal