title: Cancer therapeutics revisited; novel drugs targeting cell signalling pathways, genome wide association studies and other trials and tribulations.
authors.affiliation: Section of Clinical Pharmacology, Department of Medicine, The Geisel School of Medicine at Dartmouth & The Norris Cotton Cancer Center, One Medical Center Drive, Lebanon, New Hampshire, 03756, USA.
authors.forename: Lionel D
authors.initials: LD
authors.lastname: Lewis
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D017209:Apoptosis / Q000187:drug effects / Q000235:genetics; D055106:Genome-Wide Association Study; D006801:Humans; D058990:Molecular Targeted Therapy / Q000379:methods*; D009369:Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents
references.citation: Cell. 2011 Mar 4;144(5):646-74
references.pmid: 21376230
references.citation: Br J Clin Pharmacol. 2013 Sep;76(3):467-74
references.pmid: 23701184
references.citation: Br J Clin Pharmacol. 2013 Sep;76(3):412-24
references.pmid: 23601153
references.citation: Br J Clin Pharmacol. 2013 Sep;76(3):338-47
references.pmid: 23834355
references.citation: Br J Clin Pharmacol. 2013 Sep;76(3):370-80
references.pmid: 23701381
references.citation: Br J Clin Pharmacol. 2013 Sep;76(3):486-8
references.pmid: 23713740
references.citation: Angiology. 2006 May-Jun;57(3):367-71
references.pmid: 16703198
references.citation: Br J Clin Pharmacol. 2006 Jun;61(6):677-81
references.pmid: 16722828
references.citation: J Natl Cancer Inst. 2002 Aug 21;94(16):1247-9
references.pmid: 12189228
references.citation: Br J Clin Pharmacol. 2013 Sep;76(3):320-8
references.pmid: 23451731
references.citation: Br J Clin Pharmacol. 2006 Jul;62(1):1-4
references.pmid: 16842373
references.citation: Br J Clin Pharmacol. 2013 Sep;76(3):381-95
references.pmid: 23782006
references.citation: Br J Clin Pharmacol. 2013 Sep;76(3):358-69
references.pmid: 23593991
references.citation: Br J Clin Pharmacol. 2013 Sep;76(3):348-57
references.pmid: 23617405
references.citation: Br J Clin Pharmacol. 2013 Sep;76(3):396-411
references.pmid: 23362829
references.citation: Br J Clin Pharmacol. 2013 Sep;76(3):329-37
references.pmid: 23594375