title: Obstructive sleep apnea in patients with central serous chorioretinopathy.
abstract: OBJECTIVE
  In this study, we aimed to evaluate the relation between obstructive sleep apnea (OSA) and central serous retinopathy (CSR).
  
  
  METHODS
  Twenty-three consecutive subjects aged >18 years with the diagnosis of CSR were included in this prospective study. Overnight polysomnography was performed to all subjects. Desaturation index and apnea-hypopnea index (AHI) were recorded. Obstructive sleep apnea was classified according to AHI as mild, moderate, or severe. Statistical analysis was performed using chi-square test, Fisher's exact test, and Mann-Whitney U test.
  
  
  RESULTS
  Fourteen of 23 CSR patients (60.9%) had OSA. Prevalence of OSA was significantly higher in male subjects with CSR compared to female subjects with CSR (p = 0.018). One (16.7%) female subject with CSR had OSA whereas thirteen (76.5%) male subjects were found to have OSA. Desaturation index was found to be 5.1 ± 4.2 in females and 12.9 ± 11.1 in males (p = 0.036).
  
  
  CONCLUSIONS
  Obstructive sleep apnea is seen nearly in 2/3 of patients with the diagnosis of CSR. There are possible common pathophysiological mechanisms like oxidative stress, vasoconstriction, or blood coagulation abnormalities. Screening for OSA should be considered in subjects with the diagnosis of CSR.
authors.affiliation: Faculty of Medicine, Department of Ophthalmology, University of Afyon Kocatepe , Afyonkarahisar , Turkey and.
authors.forename: Güliz F
authors.initials: GF
authors.lastname: Yavaş
authors.forename: Tuncay
authors.initials: T
authors.lastname: Küsbeci
authors.forename: Murat
authors.initials: M
authors.lastname: Kaşikci
authors.forename: Ersin
authors.initials: E
authors.lastname: Günay
authors.forename: Mustafa
authors.initials: M
authors.lastname: Doğan
authors.forename: Mehmet
authors.initials: M
authors.lastname: Unlü
authors.forename: Umit Ü
authors.initials: UÜ
authors.lastname: Inan
mesh_terms: D000328:Adult; D000368:Aged; D001777:Blood Coagulation / Q000502:physiology; D056833:Central Serous Chorioretinopathy / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress / Q000502:physiology; D010974:Platelet Aggregation / Q000502:physiology; D017286:Polysomnography; D011446:Prospective Studies; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology*; D014661:Vasoconstriction / Q000502:physiology