title: HPV types in Turkey: multicenter hospital based evaluation of 6388 patients in Turkish gynecologic oncology group centers.
abstract: OBJECTIVE
  To evaluate the prevalence of HPV DNA and cervical cytological abnormalities, to compare cervical cytology results and HPV DNA and to define HPV types distribution in a large series of Turkish women who have undergone HPV analysis in hospitals that are members of the Turkish Gynecological Oncology Group.
  
  
  METHODS
  Between 2006 and 2010, a total of 6388 patients' data was retrospectively evaluated at 12 healthcare centers in Turkey. Demographic characteristics, cervical cytology results, HPV status and types were compared.
  
  
  RESULTS
  The mean age of the patients was 38.9±10.2. Overall, 25% of the women were found to be HPV positive. Presence of HPV-DNA among patients with abnormal and normal cytology was 52% and 27%, respectively. There was significant difference with respect to decades of life and HPV positivity (p < 0.05). HPV was positive in (within the HPV (+) patients) 37%, 9%, 27%, 20%, 22%, and 41% of the ASCUS, ASC-H, LSIL HSIL, glandular cell abnormalities, and SCC cases respectively The most common HPV types in our study were as follows; HPV 16 (32%), HPV 6 (17%), HPV 11 (9%), HPV 18 (8%), HPV 31 (6%), HPV 51 (5%), HPV 33 (3%).
  
  
  CONCLUSIONS
  In this hospital based retrospective analysis, HPV genotypes in Turkish women with normal and abnormal cytology are similar to those reported from western countries. Further population based prospective multicenter studies are necessary to determine non-hospital based HPV prevalence in Turkish women.
authors.affiliation: Department of Obstetrics and Gynecology, Başkent University, Faculty of Medicine, ANKARA, TURKEY.
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authors.lastname: Basaran
authors.forename: Hüseyin
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authors.lastname: Aydoğmuş
authors.forename: Yusuf
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authors.lastname: Ergün
authors.forename: Salim
authors.initials: S
authors.lastname: Şehıralı
authors.forename: Emre
authors.initials: E
authors.lastname: Gültekın
authors.forename: Sükran
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authors.forename: Yusuf
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authors.lastname: Yildirim
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authors.forename: Murat
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authors.forename: Ibrahim
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authors.lastname: Alanbay
authors.forename: Rıza
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authors.forename: Jale
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authors.lastname: Metındır
authors.forename: Levent
authors.initials: L
authors.lastname: Keskın
authors.forename: Işık
authors.initials: I
authors.lastname: Üstüner
authors.forename: Filiz
authors.initials: F
authors.lastname: Avşar
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mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000453:epidemiology / Q000821:virology*; D015995:Prevalence; D012189:Retrospective Studies; D014421:Turkey / Q000453:epidemiology; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000821:virology*; D055815:Young Adult; D002578:Uterine Cervical Dysplasia / Q000453:epidemiology / Q000821:virology*
chemical_list: D004279:DNA, Viral