title: [Effect of physical countermeasures against support load deficiency on the hemostasis system in an experiment with 7-day immersion].
abstract: In an experiment with 7-d dry immersion for testing the mechanic foot and electrical muscle stimulation procedures of compensating the support load deficiency the following biochemical parameters were studied: activated partial thromboplastin time, prothrombin time, prothrombin index, international normalized ratio, thrombin time (TT), fibrinogen, soluble fibrin-monomer complexes, D-dimer (DD), plasminogen (PG); antithrombin III activity (ATIII), protein C (PC) and alpha2-antiplasmin (AP). Control subjects (immersed w/o stimulation) did not exhibit significant shifts in the hemostasis system: however, they decreased ATIII, PC and PG in the post-experimental period. Mechanic foot stimulation did not have a noteworthy effect on the hemostasis system functioning during immersion, whereas electromyostimulation increased procoagulant and fibrinolytic activity in blood plasma.
authors.forename: D S
authors.initials: DS
authors.lastname: Kuzichkin
authors.forename: A A
authors.initials: AA
authors.lastname: Markin
authors.forename: B V
authors.initials: BV
authors.lastname: Morukov
authors.forename: O A
authors.initials: OA
authors.lastname: Zhuravleva
authors.forename: I V
authors.initials: IV
authors.lastname: Zabolotskaya
authors.forename: L V
authors.initials: LV
authors.lastname: Vostrikova
mesh_terms: D001780:Blood Coagulation Tests; D004558:Electric Stimulation; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D012426:Russia; D018561:Space Simulation; D013997:Time Factors; D018544:Weightlessness Countermeasures