title: Scleroderma renal crisis.
abstract: Systemic sclerosis is an autoimmune connective tissue disorder characterized by endothelial cell injury, vascular hyper-reactivity, obliterative microvasculopathy and excess collagen deposition, particularly within the dermis of the skin. Table 1 outlines the various terms that are used to describe the extent and location of sclerosis. Limited cutaneous and diffuse cutaneous are the two main forms that exist.
authors.affiliation: Core Medical Trainee in Nephrology in the UCL Centre for Nephrology, Royal Free Hospital, London.
authors.forename: Tamer
authors.initials: T
authors.lastname: Rezk
authors.forename: Scott
authors.initials: S
authors.lastname: R Henderson
authors.forename: Bernadette
authors.initials: B
authors.lastname: Lynch
authors.forename: Aine
authors.initials: A
authors.lastname: Burns
mesh_terms: D001327:Autoimmune Diseases; D003240:Connective Tissue Diseases; D006801:Humans; D012595:Scleroderma, Systemic; D012867:Skin