title: Can we vaccinate against atherosclerosis?
abstract: A large body of evidence implicates the immune system in the pathogenesis of atherosclerosis. Both active and passive immunizations have been tested as immunomodulation strategies to confer protective effect against atherogenesis. This review focuses on the current knowledge of the complex role and the potential for immune modulation therapy via active immunization for atherosclerosis.
authors.affiliation: 1Division of Cardiology, Oppenheimer Atherosclerosis Research Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
authors.forename: Kuang-Yuh
authors.initials: KY
authors.lastname: Chyu
authors.forename: Prediman K
authors.initials: PK
authors.lastname: Shah
mesh_terms: D000818:Animals; D050197:Atherosclerosis / Q000276:immunology / Q000517:prevention & control*; D006801:Humans; D007107:Immune System / Q000276:immunology; D007116:Immunization, Passive / Q000379:methods; D014611:Vaccination / Q000379:methods*; D014612:Vaccines / Q000008:administration & dosage* / Q000276:immunology
chemical_list: D014612:Vaccines
keywords: atherosclerosis; immunization; vaccine