title: Association of the GDNF gene with depression and heroin dependence, but not schizophrenia, in a Chinese population.
abstract: The association of seven GDNF tag SNPs with depression, heroin dependence (HD) and schizophrenia was evaluated in Chinese. An increased risk of HD and depression was associated with rs2910709 T/T genotype and rs884344 C allele, respectively, suggesting GDNF is a novel susceptibility gene for depression and HD.
authors.affiliation: Department of Psychiatry, The First Affiliated Hospital of Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi, China.
authors.forename: Xian-cang
authors.initials: XC
authors.lastname: Ma
authors.forename: Ce
authors.initials: C
authors.lastname: Chen
authors.forename: Feng
authors.initials: F
authors.lastname: Zhu
authors.forename: Wei
authors.initials: W
authors.lastname: Jia
authors.forename: Cheng-ge
authors.initials: CG
authors.lastname: Gao
mesh_terms: D000483:Alleles; D044466:Asian People / Q000235:genetics* / Q000523:psychology; D016022:Case-Control Studies; D003863:Depression / Q000208:ethnology / Q000235:genetics* / Q000523:psychology; D003866:Depressive Disorder / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000208:ethnology / Q000235:genetics*; D005838:Genotype; D051100:Glial Cell Line-Derived Neurotrophic Factor / Q000235:genetics*; D006556:Heroin Dependence / Q000208:ethnology / Q000235:genetics* / Q000523:psychology; D006801:Humans; D011110:Polymorphism, Genetic; D020641:Polymorphism, Single Nucleotide; D012559:Schizophrenia / Q000235:genetics; D012565:Schizophrenic Psychology
chemical_list: D051100:Glial Cell Line-Derived Neurotrophic Factor
keywords: Depression; Glial cell line-derived neurotrophic factor; Heroin