title: DNAzyme-functionalized gold nanoparticles for biosensing.
abstract: Recent progress in using DNAzyme-functionalized gold nanoparticles (AuNPs) for biosensing is summarized in this chapter. A variety of methods, including those for attaching DNA on AuNPs, detecting metal ions and small molecules by DNAzyme-functionalized AuNPs, and intracellular applications of DNAzyme-functionalized AuNPs are discussed. DNAzyme-functionalized AuNPs will increasingly play more important roles in biosensing and many other multidisciplinary applications. This chapter covers the recent advancement in biosensing applications of DNAzyme-functionalized gold nanoparticles, including the detection of metal ions, small molecules, and intracellular imaging.
authors.affiliation: Department of Chemistry and Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
authors.forename: Yu
authors.initials: Y
authors.lastname: Xiang
authors.forename: Peiwen
authors.initials: P
authors.lastname: Wu
authors.forename: Li Huey
authors.initials: LH
authors.lastname: Tan
authors.forename: Yi
authors.initials: Y
authors.lastname: Lu
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D003124:Colorimetry / Q000379:methods*; D021881:DNA, Catalytic / Q000737:chemistry* / Q000235:genetics*; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D020349:Surface Plasmon Resonance / Q000379:methods*
chemical_list: D021881:DNA, Catalytic; D006046:Gold