title: [From endoplasmic reticulum to Golgi apparatus: a secretory pathway controlled by signal molecules].
abstract: Protein transport from endoplasmic reticulum (ER) to Golgi apparatus has long been known to be a central process for protein quality control and sorting. Recent studies have revealed that a large number of signal molecules are involved in regulation of membrane trafficking through ER, ER-Golgi intermediate compartment and Golgi apparatus. These molecules can significantly change the transport rate of proteins by regulating vesicle budding and fusion. Protein transport from ER to Golgi apparatus is not only controlled by signal pathways triggered from outside the cell, it is also regulated by feedback signals from the transport pathway.
authors.affiliation: Institute of Neuroscience, Zhejiang University School of Medicine, Hangzhou 310058, China.
authors.forename: Jiasheng
authors.initials: J
authors.lastname: Wang
authors.forename: Jianhong
authors.initials: J
authors.lastname: Luo
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Zhang
mesh_terms: D004721:Endoplasmic Reticulum / Q000378:metabolism*; D006056:Golgi Apparatus / Q000378:metabolism*; D006801:Humans; D021381:Protein Transport / Q000502:physiology*; D055571:Secretory Pathway; D015398:Signal Transduction