title: A cross-species socio-emotional behaviour development revealed by a multivariate analysis.
abstract: Recent progress in affective neuroscience and social neurobiology has been propelled by neuro-imaging technology and epigenetic approach in neurobiology of animal behaviour. However, quantitative measurements of socio-emotional development remains lacking, though sensory-motor development has been extensively studied in terms of digitised imaging analysis. Here, we developed a method for socio-emotional behaviour measurement that is based on the video recordings under well-defined social context using animal models with variously social sensory interaction during development. The behaviour features digitized from the video recordings were visualised in a multivariate statistic space using principal component analysis. The clustering of the behaviour parameters suggested the existence of species- and stage-specific as well as cross-species behaviour modules. These modules were used to characterise the behaviour of children with or without autism spectrum disorders (ASDs). We found that socio-emotional behaviour is highly dependent on social context and the cross-species behaviour modules may predict neurobiological basis of ASDs.
authors.affiliation: 1] Tokyo University of Agriculture and Technology, Tokyo, Japan [2] National Institute of Neuroscience, NCNP, Tokyo, Japan [3] Saitama Medical University, Saitama, Japan.
authors.forename: Mamiko
authors.initials: M
authors.lastname: Koshiba
authors.forename: Aya
authors.initials: A
authors.lastname: Senoo
authors.forename: Koki
authors.initials: K
authors.lastname: Mimura
authors.forename: Yuka
authors.initials: Y
authors.lastname: Shirakawa
authors.forename: Genta
authors.initials: G
authors.lastname: Karino
authors.forename: Saya
authors.initials: S
authors.lastname: Obara
authors.forename: Shinpei
authors.initials: S
authors.lastname: Ozawa
authors.forename: Hitomi
authors.initials: H
authors.lastname: Sekihara
authors.forename: Yuta
authors.initials: Y
authors.lastname: Fukushima
authors.forename: Toyotoshi
authors.initials: T
authors.lastname: Ueda
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Kishino
authors.forename: Toshihisa
authors.initials: T
authors.lastname: Tanaka
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Ishibashi
authors.forename: Hideo
authors.initials: H
authors.lastname: Yamanouchi
authors.forename: Kunio
authors.initials: K
authors.lastname: Yui
authors.forename: Shun
authors.initials: S
authors.lastname: Nakamura
mesh_terms: D000293:Adolescent; D000339:Affect; D000819:Animal Communication; D000818:Animals; D002144:Callithrix; D002645:Chickens; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000523:psychology; D004644:Emotions; D005260:Female; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D015999:Multivariate Analysis; D025341:Principal Component Analysis; D012919:Social Behavior
references.citation: PLoS Biol. 2005 Jul;3(7):e208
references.pmid: 15934787
references.citation: Neuron. 2010 Mar 25;65(6):768-79
references.pmid: 20346754
references.citation: J Neurodev Disord. 2012 May 24;4(1):14
references.pmid: 22958572
references.citation: Nat Neurosci. 2004 Oct;7(10):1048-54
references.pmid: 15452576
references.citation: Nat Rev Neurosci. 2005 Oct;6(10):766-74
references.pmid: 16276354
references.citation: J Neurosci. 2003 Apr 15;23(8):3483-90
references.pmid: 12716957
references.citation: Trends Cogn Sci. 2004 Sep;8(9):396-403
references.pmid: 15350240
references.citation: Nat Rev Neurosci. 2009 Jan;10(1):59-70
references.pmid: 19096369
references.citation: Psychol Rev. 2003 Jan;110(1):145-72
references.pmid: 12529060
references.citation: Philos Trans R Soc Lond B Biol Sci. 2003 Mar 29;358(1431):593-602
references.pmid: 12689384
references.citation: Science. 2004 Jun 25;304(5679):1983-6
references.pmid: 15218152
references.citation: Neuropsychologia. 1994 Apr;32(4):417-23
references.pmid: 8047249
references.citation: Ann N Y Acad Sci. 2004 Dec;1036:106-27
references.pmid: 15817733
references.citation: PLoS Comput Biol. 2012;8(3):e1002385
references.pmid: 22412358
references.citation: PLoS One. 2011 Apr 20;6(4):e18802
references.pmid: 21533093
references.citation: Psychol Rev. 1991 Apr;98(2):164-81
references.pmid: 2047512
references.citation: Neuron. 2010 Mar 25;65(6):780-94
references.pmid: 20346755
references.citation: Neuron. 2010 Mar 25;65(6):752-67
references.pmid: 20346753
references.citation: J Clin Psychopharmacol. 2012 Apr;32(2):200-6
references.pmid: 22370992
references.citation: Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19762-6
references.pmid: 18077409
references.citation: Trends Cogn Sci. 2012 Jan;16(1):72-80
references.pmid: 22177032
references.citation: Nat Rev Neurosci. 2008 Apr;9(4):267-77
references.pmid: 18354399
references.citation: Brain. 2002 Aug;125(Pt 8):1839-49
references.pmid: 12135974
references.citation: J Neurosci. 2000 Apr 1;20(7):2683-90
references.pmid: 10729349
references.citation: Neuropsychopharmacology. 2009 Dec;34(13):2655-66
references.pmid: 19710635
references.citation: Nature. 2009 May 28;459(7246):523-7
references.pmid: 19478777
references.citation: Curr Biol. 2006 Apr 18;16(8):R279-80
references.pmid: 16631570
references.citation: Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 1;35(6):1493-8
references.pmid: 21238530
references.citation: PLoS One. 2011;6(9):e21236
references.pmid: 21915252
references.citation: Dev Sci. 2010 Jul;13(4):565-77
references.pmid: 20590721
references.citation: Neurosci Lett. 2013 Jun 28;547:70-5
references.pmid: 23689249
references.citation: Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4483-5
references.pmid: 20160095
references.citation: Nat Neurosci. 2009 Feb;12(2):200-9
references.pmid: 19151710
references.citation: PLoS One. 2012;7(11):e49019
references.pmid: 23139831
references.citation: Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):809-13
references.pmid: 18174333
references.citation: Trends Neurosci. 1998 Jul;21(7):306-11
references.pmid: 9683323
references.citation: Brain. 2005 Oct;128(Pt 10):2430-41
references.pmid: 15958508
references.citation: Anim Cogn. 2010 May;13(3):555-64
references.pmid: 20052512
references.citation: Ann N Y Acad Sci. 2003 Oct;1001:253-61
references.pmid: 14625365
references.citation: Neuron. 2005 May 19;46(4):681-92
references.pmid: 15944135
references.citation: Nat Neurosci. 2004 Aug;7(8):847-54
references.pmid: 15220929
references.citation: Autism Res. 2012 Aug;5(4):231-44
references.pmid: 22447729
references.citation: Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 1;35(6):1499-504
references.pmid: 21300127
references.citation: Sci Rep. 2013;3:2503
references.pmid: 23974241
references.citation: Nat Rev Neurosci. 2004 Feb;5(2):108-20
references.pmid: 14735114
references.citation: J Neuroendocrinol. 2011 Nov;23(11):1054-65
references.pmid: 21951160
references.citation: Nat Neurosci. 2009 Aug;12(8):970-2
references.pmid: 19578379
references.citation: Ann N Y Acad Sci. 2003 Dec;1000:337-47
references.pmid: 14766647
references.citation: PLoS One. 2013;8(3):e58847
references.pmid: 23520539
references.citation: Nat Neurosci. 2006 Sep;9(9):1094-5
references.pmid: 16921371