title: Life tables adjusted for comorbidity more accurately estimate noncancer survival for recently diagnosed cancer patients.
abstract: OBJECTIVE
  To provide cancer patients and clinicians with more accurate estimates of a patient's life expectancy with respect to noncancer mortality, we estimated comorbidity-adjusted life tables and health-adjusted age.
  
  
  METHODS
  Using data from the Surveillance Epidemiology and End Results-Medicare database, we estimated comorbidity scores that reflect the health status of people who are 66 years of age and older in the year before cancer diagnosis. Noncancer survival by comorbidity score was estimated for each age, race, and sex. Health-adjusted age was estimated by systematically comparing the noncancer survival models with US life tables.
  
  
  RESULTS
  Comorbidity, cancer status, sex, and race are all important predictors of noncancer survival; however, their relative impact on noncancer survival decreases as age increases. Survival models by comorbidity better predicted noncancer survival than the US life tables. The health-adjusted age and national life tables can be consulted to provide an approximate estimate of a person's life expectancy, for example, the health-adjusted age of a black man aged 75 years with no comorbidities is 67 years, giving him a life expectancy of 13 years.
  
  
  CONCLUSIONS
  The health-adjusted age and the life tables adjusted by age, race, sex, and comorbidity can provide important information to facilitate decision making about treatment for cancer and other conditions.
authors.affiliation: Division of Cancer Control and Population Sciences, National Cancer Institute, 9609 Medical Center Drive, Bethesda, MD 20892, USA. Electronic address: mariotta@mail.nih.gov.
authors.forename: Angela B
authors.initials: AB
authors.lastname: Mariotto
authors.forename: Zhuoqiao
authors.initials: Z
authors.lastname: Wang
authors.forename: Carrie N
authors.initials: CN
authors.lastname: Klabunde
authors.forename: Hyunsoon
authors.initials: H
authors.lastname: Cho
authors.forename: Barnali
authors.initials: B
authors.lastname: Das
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Feuer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005260:Female; D006801:Humans; D008017:Life Expectancy / Q000208:ethnology; D015993:Life Tables; D008297:Male; D009369:Neoplasms / Q000175:diagnosis / Q000453:epidemiology*; D044469:Racial Groups / Q000706:statistics & numerical data; D015203:Reproducibility of Results; D018426:SEER Program; D016019:Survival Analysis; D014481:United States / Q000453:epidemiology
keywords: Cancer; Comorbidity; Health-adjusted age; Life expectancy; Life tables; SEER–Medicare; Survival
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