title: Aortic stenosis and mitral regurgitation: implications for transcatheter valve treatment.
abstract: Moderate or severe mitral regurgitation (MR) is a common finding in patients with severe aortic stenosis (AS). The combination may be a relative indication for double valve surgery, particularly when MR is severe, degenerative, associated with left atrial dilation, chronic atrial fibrillation, or mitral annular calcium. However, in patients for whom open surgery is not desirable, TAVI may provide a reasonable therapeutic strategy with an expectation in selected patients that MR may improve, be better tolerated, or be amenable to staged transcatheter mitral interventions. In this paper, we briefly review the surgical experience with concomitant AS and MR and discuss the potential implications of transcatheter-based heart valve techniques in this patient group.
authors.affiliation: St. Paul's Hospital, University of British Columbia, Vancouver, Canada.
authors.forename: Marco
authors.initials: M
authors.lastname: Barbanti
authors.forename: Danny
authors.initials: D
authors.lastname: Dvir
authors.forename: John
authors.initials: J
authors.lastname: Tan
authors.forename: John G
authors.initials: JG
authors.lastname: Webb
mesh_terms: D001021:Aortic Valve; D001024:Aortic Valve Stenosis / Q000453:epidemiology / Q000628:therapy*; D006328:Cardiac Catheterization; D015897:Comorbidity; D019468:Disease Management; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008943:Mitral Valve; D008944:Mitral Valve Insufficiency / Q000453:epidemiology / Q000628:therapy*; D012307:Risk Factors; D012720:Severity of Illness Index; D016896:Treatment Outcome