title: Pediatricians' perceptions of vaccine effectiveness and safety are significant predictors of vaccine administration in India.
abstract: BACKGROUND
  New vaccine introduction is important to decrease morbidity and mortality in India. The goal of this study was to identify perceptions that are associated with administration of four selected vaccines for prevention of Japanese encephalitis (JE), typhoid fever, influenza and human papillomavirus (HPV) infection.
  
  
  METHODS
  A random sample of 785 pediatricians from a national list of Indian Academy of Pediatrics members was selected for a survey to assess perceptions of vaccine effectiveness and safety, and vaccine administration practices. Logistic regression was used to assess factors associated with selective or routine use.
  
  
  RESULTS
  Pediatricians reported administering typhoid (91.6%), influenza (60.1%), HPV (46.0%) and JE (41.9%) vaccines selectively or routinely. Pediatricians who perceived the vaccine to be safe were significantly more likely to report administration of JE (OR 2.6, 95% CI 1.3 to 5.3), influenza (OR 4.3, 95% CI 2.0 to 9.6) and HPV vaccine (OR 6.2, 95% CI 3.1 to 12.7). Pediatricians who perceived the vaccine to be effective were significantly more likely to report administration of JE (OR 3.3, 95% CI 1.6 to 6.5), influenza (OR 7.7, 95% CI 2.5 to 23.1) and HPV vaccine (OR 3.2, 95% CI 1.6 to 6.4) CONCLUSION: Understanding the role perceptions play provides an opportunity to design strategies to build support for vaccine use.
authors.affiliation: Emory University, School of Medicine, 1462 Clifton Road NE, Room 446, Atlanta, GA 30322, USA.
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Gargano
authors.forename: Naveen
authors.initials: N
authors.lastname: Thacker
authors.forename: Panna
authors.initials: P
authors.lastname: Choudhury
authors.forename: Paul S
authors.initials: PS
authors.lastname: Weiss
authors.forename: Rebecca M
authors.initials: RM
authors.lastname: Russ
authors.forename: Karen
authors.initials: K
authors.lastname: Pazol
authors.forename: Manisha
authors.initials: M
authors.lastname: Arora
authors.forename: Walter A
authors.initials: WA
authors.lastname: Orenstein
authors.forename: Saad B
authors.initials: SB
authors.lastname: Omer
authors.forename: James M
authors.initials: JM
authors.lastname: Hughes
mesh_terms: D001291:Attitude of Health Personnel; D006801:Humans; D007194:India; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000009:adverse effects; D022321:Japanese Encephalitis Vaccines / Q000008:administration & dosage / Q000009:adverse effects; D016017:Odds Ratio; D053918:Papillomavirus Vaccines / Q000008:administration & dosage / Q000009:adverse effects; D061214:Patient Safety; D010372:Pediatrics; D010820:Physicians; D016896:Treatment Outcome; D014436:Typhoid-Paratyphoid Vaccines / Q000008:administration & dosage / Q000009:adverse effects; D014611:Vaccination / Q000009:adverse effects; D014612:Vaccines / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D007252:Influenza Vaccines; D022321:Japanese Encephalitis Vaccines; D053918:Papillomavirus Vaccines; D014436:Typhoid-Paratyphoid Vaccines; D014612:Vaccines
keywords: Human papillomavirus vaccine; India; Influenza vaccine; Japanese encephalitis vaccine; Typhoid vaccine
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