title: [The mechanism of the antitumor effect of total/subtotal radiotherapy with non-tumoricidal doses of radiation].
abstract: The myelodepression at therapy for solid malignancies is considered as a mediating element of common antineoplastic activity on the basis of ability of stem cells of hemapoietic system to participate in regeneration of the various tissues of the body, including tumor. The equivalence of the therapeutic benefit mediated by both mild myelodepression due to total/subtotal radiation exposure and conventional chemotherapy with cytotoxic drugs is argued.
authors.forename: A N
authors.initials: AN
authors.lastname: Shutko
authors.forename: I V
authors.initials: IV
authors.lastname: Akushevich
authors.forename: L P
authors.initials: LP
authors.lastname: Ekimova
authors.forename: V F
authors.initials: VF
authors.lastname: Mus
authors.forename: B P
authors.initials: BP
authors.lastname: Sokurenko
authors.forename: L E
authors.initials: LE
authors.lastname: Iurkova
authors.forename: K S
authors.initials: KS
authors.lastname: Matiurin
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001853:Bone Marrow / Q000528:radiation effects*; D003037:Cobalt Radioisotopes / Q000008:administration & dosage* / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D012189:Retrospective Studies
chemical_list: D000970:Antineoplastic Agents; D003037:Cobalt Radioisotopes