title: Changing the mind? Not really-activity and connectivity in the caudate correlates with changes of choice.
abstract: Changes in preference are inherently subjective and internal psychological events. We have identified brain events that presage ultimate (rather than intervening) choices, and signal the finality of a choice. At the first exposure to a pair of faces, caudate activity reflected the face of final choice, even if an initial choice was different. Furthermore, the orbitofrontal cortex and hippocampus exhibited correlations only when the subject had made a choice that would not change.
authors.affiliation: Brain Science Institute, Tamagawa University, 6-1-1, Tamagawa Gakuen, Machida, Tokyo 194-8610, Japan, Division of Biology/Option Representative, Computation and Neural Systems, California Institute of Technology, 139-74, Pasadena, CA 91125, USA, and Department of Pharmacology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
authors.forename: Takehito
authors.initials: T
authors.lastname: Ito
authors.affiliation: Brain Science Institute, Tamagawa University, 6-1-1, Tamagawa Gakuen, Machida, Tokyo 194-8610, Japan, Division of Biology/Option Representative, Computation and Neural Systems, California Institute of Technology, 139-74, Pasadena, CA 91125, USA, and Department of Pharmacology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
authors.forename: Daw-An
authors.initials: DA
authors.lastname: Wu
authors.affiliation: Brain Science Institute, Tamagawa University, 6-1-1, Tamagawa Gakuen, Machida, Tokyo 194-8610, Japan, Division of Biology/Option Representative, Computation and Neural Systems, California Institute of Technology, 139-74, Pasadena, CA 91125, USA, and Department of Pharmacology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Marutani
authors.affiliation: Brain Science Institute, Tamagawa University, 6-1-1, Tamagawa Gakuen, Machida, Tokyo 194-8610, Japan, Division of Biology/Option Representative, Computation and Neural Systems, California Institute of Technology, 139-74, Pasadena, CA 91125, USA, and Department of Pharmacology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
authors.forename: Manami
authors.initials: M
authors.lastname: Yamamoto
authors.affiliation: Brain Science Institute, Tamagawa University, 6-1-1, Tamagawa Gakuen, Machida, Tokyo 194-8610, Japan, Division of Biology/Option Representative, Computation and Neural Systems, California Institute of Technology, 139-74, Pasadena, CA 91125, USA, and Department of Pharmacology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Suzuki
authors.affiliation: Brain Science Institute, Tamagawa University, 6-1-1, Tamagawa Gakuen, Machida, Tokyo 194-8610, Japan, Division of Biology/Option Representative, Computation and Neural Systems, California Institute of Technology, 139-74, Pasadena, CA 91125, USA, and Department of Pharmacology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Shimojo
authors.affiliation: Brain Science Institute, Tamagawa University, 6-1-1, Tamagawa Gakuen, Machida, Tokyo 194-8610, Japan, Division of Biology/Option Representative, Computation and Neural Systems, California Institute of Technology, 139-74, Pasadena, CA 91125, USA, and Department of Pharmacology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan tetsuya@lab.tamagawa.ac.jp sshimojo@caltech.edu.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Matsuda
mesh_terms: D000293:Adolescent; D001288:Attention / Q000502:physiology*; D001921:Brain / Q000098:blood supply / Q000502:physiology*; D001931:Brain Mapping; D002755:Choice Behavior / Q000502:physiology*; D005145:Face; D005260:Female; D005403:Fixation, Ocular; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016014:Linear Models; D008279:Magnetic Resonance Imaging; D008297:Male; D010100:Oxygen / Q000097:blood; D010364:Pattern Recognition, Visual / Q000502:physiology*; D010775:Photic Stimulation; D055815:Young Adult
chemical_list: D010100:Oxygen
keywords: caudate; changing mind; fMRI; face preference; gaze manipulation
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