title: [The diversity of ghrelin gene in its products and functions].
abstract: By alternative splicing and posttranslational modification, ghrelin gene encodes multiple products ranging from acyl-ghrelin, des-acyl-ghrelin, to obestatin. These products exhibit diverse functions such as stimulating growth hormone secretion, regulating food uptake, glucose and lipid metabolism, protecting cardiovascular system, and modulating immune and inflammation. This review summarizes the recent advances on the products of ghrelin gene and their diverse functions.
authors.affiliation: Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100191, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Tang
authors.forename: Wei-Zhen
authors.initials: WZ
authors.lastname: Zhang
mesh_terms: D054439:Ghrelin / Q000235:genetics* / Q000502:physiology*; D005947:Glucose / Q000378:metabolism; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D007109:Immunity / Q000502:physiology; D007249:Inflammation / Q000503:physiopathology; D050356:Lipid Metabolism / Q000502:physiology
chemical_list: D054439:Ghrelin; C422650:ghrelin, des-n-octanoyl; D013006:Growth Hormone; D005947:Glucose