title: Cerebral and splenic infarctions after injection of N-butyl-2-cyanoacrylate in esophageal variceal bleeding.
abstract: Variceal bleeding is the most serious complication of portal hypertension, and it accounts for approximately one fifth to one third of all deaths in liver cirrhosis patients. Currently, endoscopic treatment remains the predominant method for the prevention and treatment of variceal bleeding. Endoscopic treatments include band ligation and injection sclerotherapy. Injection sclerotherapy with N-butyl-2-cyanoacrylate has been successfully used to treat variceal bleeding. Although injection sclerotherapy with N-butyl-2-cyanoacrylate provides effective treatment for variceal bleeding, injection of N-butyl-2-cyanoacrylate is associated with a variety of complications, including systemic embolization. Herein, we report a case of cerebral and splenic infarctions after the injection of N-butyl-2-cyanoacrylate to treat esophageal variceal bleeding.
authors.affiliation: Dae-Seong Myung, Cho-Yun Chung, Hyung-Chul Park, Jong-Sun Kim, Sung-Bum Cho, Wan-Sik Lee, Sung-Kyu Choi, Young-Eun Joo, Department of Internal Medicine, Chonnam National University Medical School, Gwangju 501-757, South Korea.
authors.forename: Dae-Seong
authors.initials: DS
authors.lastname: Myung
authors.forename: Cho-Yun
authors.initials: CY
authors.lastname: Chung
authors.forename: Hyung-Chul
authors.initials: HC
authors.lastname: Park
authors.forename: Jong-Sun
authors.initials: JS
authors.lastname: Kim
authors.forename: Sung-Bum
authors.initials: SB
authors.lastname: Cho
authors.forename: Wan-Sik
authors.initials: WS
authors.lastname: Lee
authors.forename: Sung-Kyu
authors.initials: SK
authors.lastname: Choi
authors.forename: Young-Eun
authors.initials: YE
authors.lastname: Joo
mesh_terms: D002544:Cerebral Infarction / Q000209:etiology*; D004659:Enbucrilate / Q000008:administration & dosage / Q000009:adverse effects*; D004932:Esophageal and Gastric Varices / Q000150:complications / Q000628:therapy*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007267:Injections; D008875:Middle Aged; D015911:Sclerotherapy / Q000009:adverse effects*; D013159:Splenic Infarction / Q000209:etiology*
chemical_list: D004659:Enbucrilate
keywords: Cerebrum; Esophageal varix; Infarction; N-butyl-2-cyanoacrylate; Spleen
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