title: Tumor-like growth of giant inflammatory polyposis in a patient with ulcerative colitis.
abstract: We report a unique case of giant obstructing inflammatory polyposis associated with ulcerative colitis (UC). A 25-year-old Japanese man with an UC history of 2 years and 6 months was referred to our institution because of diarrhea and melena. His computed tomography scan showed marked dilation of the transverse and descending colon; therefore, we performed total colectomy. Macroscopic evaluation of the excised specimen indicated constricting lesions with giant polyposis in the transverse and descending colon. The polyposis consisted of narrow worm- or noodle-like polyps that bridged over the irregular ulcers. Histologic evaluation of the excised specimen indicated transmural inflammation with a thickened proper muscular layer overlaid with inflammatory polyposis. Based on these data, a diagnosis of giant inflammatory polyposis should be considered in patients who have had UC. Although giant inflammatory polyposis is considered benign, surgical treatment may be indicated to avoid serious complications.
authors.affiliation: Department of Surgery, Toho University Sakura Medical Center, Sakura, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Nagashima
authors.forename: Yui
authors.initials: Y
authors.lastname: Sugishita
authors.forename: Ayako
authors.initials: A
authors.lastname: Moriyama
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Ooshiro
authors.forename: Kengo
authors.initials: K
authors.lastname: Kadoya
authors.forename: Ayami
authors.initials: A
authors.lastname: Sato
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Kitahara
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Takagi
authors.forename: Tasuku
authors.initials: T
authors.lastname: Urita
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yoshida
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tanaka
authors.forename: Takashi
authors.initials: T
authors.lastname: Oshiro
authors.forename: Kentaro
authors.initials: K
authors.lastname: Nakamura
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Hiruta
authors.forename: Shinichi
authors.initials: S
authors.lastname: Okazumi
authors.forename: Ryoji
authors.initials: R
authors.lastname: Katoh
keywords: Filiform polyposis; Giant inflammatory polyposis; Inflammatory bowel disease; Ulcerative colitis
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