title: Detection of Mogibacterium timidum in subgingival biofilm of aggressive and non-diabetic and diabetic chronic periodontitis patients.
abstract: The aim of the present study was to evaluate the frequency of detection of Mogibacterium timidum in subgingival samples of subjects with generalized aggressive periodontitis (GAgP) and uncontrolled diabetic and non-diabetic subjects with generalized chronic periodontitis (GChP). 48 patients with GAgP, 50 non-diabetic and 39 uncontrolled (glycated hemoglobin >7%) type 2 diabetic subjects with GChP were enrolled in this study. Subgingival biofilm were collected from deep pockets (probing depth > 7 mm). After DNA extraction, M. timidum was detected by Nested Polymerase Chain Reaction and chi-square test was used to data analysis (p>0.05). There were no differences in the frequency of detection of M. timidum between subjects with GAgP (35%) and non-diabetic subjects with GChP (40%) (p>0.05). The frequency of detection of M. timidum was significantly higher in deep pockets of diabetic subjects with GChP (56%) when compared to GAgP (p<0.05), but similar to non-diabetic subjects with GChP (p>0.05). The frequency of detection of M. timidum was higher in subjects GChP presenting uncontrolled type 2 diabetes mellitus, when compared to GAgP subjects.
authors.affiliation: Divisião de Periodontia, Universidade Paulista , São Paulo, SP , Brasil ; Departamento de Prótese e Periodontia, Universidade Estadual de Campinas , Piracicaba, SP , Brasil.
authors.forename: Renato Corrêa Viana
authors.initials: RC
authors.lastname: Casarin
authors.forename: Daniel
authors.initials: D
authors.lastname: Saito
authors.forename: Vanessa Renata
authors.initials: VR
authors.lastname: Santos
authors.forename: Suzana Peres
authors.initials: SP
authors.lastname: Pimentel
authors.forename: Poliana Mendes
authors.initials: PM
authors.lastname: Duarte
authors.forename: Márcio Zaffalon
authors.initials: MZ
authors.lastname: Casati
authors.forename: Reginaldo Bruno
authors.initials: RB
authors.lastname: Gonçalves
keywords: Aggressive periodontitis; Chronic periodontitis; Diabetes mellitus; Mogibacterium timidum
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