title: Fusobacterium spp. and colorectal cancer: cause or consequence?
abstract: Although increasing evidence suggests a relationship between bacterial dysbiosis and colorectal cancer (CRC), few studies have identified specific microbial etiologic factors. Recent studies have implicated overabundance of Fusobacterium in association with colorectal adenomas and cancer. Two articles published in Cell Host & Microbe provide insights into the Fusobacterium-CRC relationship.
authors.affiliation: Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: tokeku@med.unc.edu.
authors.forename: Temitope O
authors.initials: TO
authors.lastname: Keku
authors.forename: Amber N
authors.initials: AN
authors.lastname: McCoy
authors.forename: Andrea M
authors.initials: AM
authors.lastname: Azcarate-Peril
mesh_terms: D018829:Adhesins, Bacterial / Q000378:metabolism*; D000818:Animals; D015820:Cadherins / Q000378:metabolism*; D063646:Carcinogenesis / Q000276:immunology*; D015179:Colorectal Neoplasms / Q000276:immunology* / Q000382:microbiology*; D016967:Fusobacterium nucleatum / Q000276:immunology* / Q000378:metabolism* / Q000472:pathogenicity*; D006801:Humans; D015398:Signal Transduction; D037521:Virulence Factors / Q000378:metabolism*; D051176:beta Catenin / Q000378:metabolism*
chemical_list: D018829:Adhesins, Bacterial; D015820:Cadherins; D037521:Virulence Factors; D051176:beta Catenin
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