title: Influence of the 3K3A-activated protein C variant on the plasma clot lysis activity of t-PA and of t-PA on the variant's anticoagulant activity.
authors.affiliation: Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA.
authors.forename: L O
authors.initials: LO
authors.lastname: Mosnier
authors.forename: J A
authors.initials: JA
authors.lastname: Fernández
authors.forename: T P
authors.initials: TP
authors.lastname: Davis
authors.forename: B V
authors.initials: BV
authors.lastname: Zlokovic
authors.forename: J H
authors.initials: JH
authors.lastname: Griffin
mesh_terms: D000409:Alanine / Q000235:genetics; D000925:Anticoagulants / Q000378:metabolism*; D001777:Blood Coagulation; D004305:Dose-Response Relationship, Drug; D014644:Genetic Variation; D006801:Humans; D007511:Ischemia / Q000473:pathology / Q000628:therapy; D009154:Mutation; D010314:Partial Thromboplastin Time; D010958:Plasminogen / Q000378:metabolism; D011486:Protein C / Q000235:genetics* / Q000378:metabolism; D011994:Recombinant Proteins / Q000378:metabolism; D020521:Stroke / Q000473:pathology / Q000628:therapy; D013917:Thrombin / Q000378:metabolism; D015912:Thrombolytic Therapy; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000378:metabolism*
chemical_list: D000925:Anticoagulants; D011486:Protein C; D011994:Recombinant Proteins; D010958:Plasminogen; D013917:Thrombin; D010959:Tissue Plasminogen Activator; D000409:Alanine
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