title: Epidermodysplasia verruciformis associated with HPV 10.
abstract: Epidermodysplasia verruciformis (EV) is a rare, inherited dermatologic condition demonstrating an increased susceptibility to specific HPV genotypes, resulting in both benign and malignant skin lesions. Epidermodysplasia verruciformis lesions are frequently described as pityriasis versicolor-like scaly macules, flat wart-like papules, or verrucous and seborrhic keratosis-like papules and plaques. Acquired EV has been described in patients with HIV and in those who are on immunosuppressive therapy. We discuss a patient with congenital EV who presents with skin lesions associated with HPV 10, a less frequently cited causative subtype, and histological findings that are not classic for EV.
authors.affiliation: Department of Dermatology, Medical Faculty Associates, George Washington University, Washington, DC.
authors.forename: Amir
authors.initials: A
authors.lastname: Zahir
authors.forename: Lauren
authors.initials: L
authors.lastname: Craig
authors.forename: Peter
authors.initials: P
authors.lastname: Rady
authors.forename: Stephen
authors.initials: S
authors.lastname: Tyring
authors.forename: Alison
authors.initials: A
authors.lastname: Ehrlich
mesh_terms: D000328:Adult; D052685:Alphapapillomavirus / Q000302:isolation & purification / Q000472:pathogenicity*; D015344:DNA Probes, HPV; D004279:DNA, Viral / Q000235:genetics; D004819:Epidermodysplasia Verruciformis / Q000151:congenital / Q000235:genetics / Q000473:pathology / Q000821:virology*; D020022:Genetic Predisposition to Disease; D006801:Humans; D017403:In Situ Hybridization; D008297:Male; D030361:Papillomavirus Infections / Q000150:complications* / Q000821:virology; D016133:Polymerase Chain Reaction
chemical_list: D015344:DNA Probes, HPV; D004279:DNA, Viral