title: Efficacy of nonsurgical periodontal therapy on glycaemic control in type II diabetic patients: a randomized controlled clinical trial.
abstract: OBJECTIVE
  Diabetes and periodontal disease are two common diseases with high prevalence rates. Recent evidence has shown a bidirectional relationship between diabetes and periodontitis. The aim of this study was to investigate the effects of nonsurgical periodontal therapy on glycemic control in type 2 diabetes mellitus patients.
  
  
  METHODS
  Sixty subjects aged 35-45 years with blood sugar controlled by oral hypoglycaemic agents were randomly divided equally among 3 groups: group A (scaling, mouthwash, and brushing), group B (mouthwash and brushing), and group C (brushing only). Glycated haemoglobin (HbA1c), fasting blood sugar (FBS), probing pocket depth (PPD), gingival index (GI), plaque index (PI), and the relevant drug history were recorded at baseline and after 3 months of intervention. Comparison of the mean difference among the variables was performed by parametric and nonparametric tests, which were further evaluated using multiple regression analysis.
  
  
  RESULTS
  The mean differences between the PPD, FBS, HbA1c, GI, and PI in groups A and B were found to be statistically significant (P<0.001). Multiple regression analysis in group A showed that out of all the independent variables, GI and frequency of drug administration independently (b=0.3761 and b=0.598) showed a significantly greater impact on HbA1c (R(2)=0.832, P<0.05).
  
  
  CONCLUSIONS
  Nonsurgical periodontal therapy can effectively decrease HbA1c levels in type 2 diabetes mellitus patients on medication.
authors.affiliation: Department of Public Health Dentistry, Kothiwal Dental College & Research Centre, Moradabad, India.
authors.forename: Ravishankar Lingesha
authors.initials: RL
authors.lastname: Telgi
authors.forename: Vaibhav
authors.initials: V
authors.lastname: Tandon
authors.forename: Pradeep Shankar
authors.initials: PS
authors.lastname: Tangade
authors.forename: Amit
authors.initials: A
authors.lastname: Tirth
authors.forename: Sumit
authors.initials: S
authors.lastname: Kumar
authors.forename: Vipul
authors.initials: V
authors.lastname: Yadav
keywords: Glycosylated hemoglobin A; Periodontal debridement; Type II diabetes mellitus
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