title: Giant basal cell carcinoma of the anterior chest wall with bone invasion.
abstract: Giant basal cell carcinoma (BCC) of the chest wall is rare and poses challenges related to resection and reconstruction. A 69-year old man presented with giant BCC invading sternum. Wide resection and reconstruction with polymethylmethacrylate and mesh was performed. The soft tissue defect was covered with a pedicled omental flap and skin graft. He developed an infection requiring removal of the mesh construct; however, debridement and antibiotics cleared the infection. This case illustrates the locally aggressive nature of this disease and the need for tertiary-level care.
authors.affiliation: Department of Orthopaedics and Rehabilitation, University of Florida, Gainesville, FL, USA.
authors.forename: Lukas M
authors.initials: LM
authors.lastname: Nystrom
authors.forename: C Parker
authors.initials: CP
authors.lastname: Gibbs
authors.forename: Dhruv
authors.initials: D
authors.lastname: Singhal
authors.forename: Charles T
authors.initials: CT
authors.lastname: Klodell
mesh_terms: D000368:Aged; D002280:Basal Cell Carcinoma; D006801:Humans; D008297:Male; D011859:Radiography; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms; D013249:Sternum / Q000000981:diagnostic imaging / Q000473:pathology; D013524:Surgical Flaps; D013899:Thoracic Neoplasms; D035441:Thoracic Wall / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery
keywords: Cancer; Chest wall; Reconstruction