title: Assessment of chemomechanical removal of carious lesions using Papacarie Duo™: randomized longitudinal clinical trial.
abstract: BACKGROUND
  Chemomechanical removal of carious lesions consists of the dissolution of carious tissue by the application of a natural or synthetic agent, followed by atraumatic mechanical removal.
  
  
  OBJECTIVE
  The aim of the present study was to assess the effectiveness of Papacarie Duo ® gel in the chemomechanical removal of carious lesions in primary teeth in comparison to the traditional method (low-speed bur).
  
  
  METHODS
  A randomized clinical trial was conducted with 20 children between 5 and 8 years of age.
  
  
  METHODS
  Two teeth were treated in each child (split-mouth design), with the randomization of two methods: Group 1 - chemomechanical caries removal with Papacarie Duo™; and Group 2 - removal of carious dentin tissue using a low-speed bur. Both methods involved restoration with glass ionomer cement and follow up. The following aspects were evaluated: time required for the procedure; pain (face evaluation scale); retention of the restorative material in the cavity; and the presence of secondary caries after 30 days.
  
  
  METHODS
  Chi-squared test, Student's t-test, and Wilcoxon test.
  
  
  RESULTS
  No statistically significant differences between methods were found regarding time required for the procedure (P = 0.13), the occurrence of pain (P = 0.585), or restoration status at the 30-day clinical evaluation (P = 0.713).
  
  
  CONCLUSIONS
  The findings of the present study demonstrate that the two methods achieve similar results. The advantages of minimally invasive treatment, such as chemomechanical caries removal with Papacarie Duo™, are its ease of use, patient comfort, and the fact that it causes less damage to dental tissue.
authors.affiliation: Department of Rehabilitation Sciences Post Graduation Program, Nove de Julho University (UNINOVE), São Paulo, Brazil.
authors.forename: Simone Ferreira Borges
authors.initials: SF
authors.lastname: Matsumoto
authors.forename: Lara Jansiski
authors.initials: LJ
authors.lastname: Motta
authors.forename: Thays Almeida
authors.initials: TA
authors.lastname: Alfaya
authors.forename: Carolina Cardoso
authors.initials: CC
authors.lastname: Guedes
authors.forename: Kristianne Porta Santos
authors.initials: KP
authors.lastname: Fernandes
authors.forename: Sandra Kalil
authors.initials: SK
authors.lastname: Bussadori
mesh_terms: D002648:Child; D002675:Child, Preschool; D003731:Dental Caries / Q000628:therapy*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D010206:Papain / Q000627:therapeutic use*
chemical_list: C509557:Papacarie; D010206:Papain