title: Hepatocellular carcinoma that arose from primary Sjögren's syndrome.
abstract: Hepatocellular carcinoma (HCC) typically originates from HBV or HCV associated liver cirrhosis. Primary Sjögren's syndrome (pSS) is a kind of autoimmune disease. A sixty-two year old female patient with mild liver damage was diagnosed with pSS after excluding viral, alcoholic and drug-induced hepatitis according to serum immunological detection and liver biopsy. But when she was hospitalized for a second time two years later, a CT scan revealed liver neoplasm. Surgery confirmed HCC and liver cirrhosis by pathology. The elevated level of AFP recovered to normal after tumorectomy. In conclusion, HCC might be a candidate outcome in patients with pSS; it is the doctors' responsibility to keep this kind of patient under surveillance.
authors.affiliation: Department of Gastroenterology and.
authors.forename: Ming-Xian
authors.initials: MX
authors.lastname: Yan
authors.forename: Jing
authors.initials: J
authors.lastname: Yang
authors.forename: Qing
authors.initials: Q
authors.lastname: Sun
authors.forename: Chang-Hong
authors.initials: CH
authors.lastname: Liu
authors.forename: Yi-Guo
authors.initials: YG
authors.lastname: Wang
authors.forename: Wen-Qi
authors.initials: WQ
authors.lastname: Wang
mesh_terms: D001706:Biopsy; D006528:Carcinoma, Hepatocellular / Q000097:blood / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008103:Liver Cirrhosis / Q000209:etiology; D008113:Liver Neoplasms / Q000097:blood / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D000509:alpha-Fetoproteins / Q000378:metabolism
chemical_list: C097353:AFP protein, human; D000509:alpha-Fetoproteins