title: [Diagnosis of and therapy for choroidal melanoma].
abstract: BACKGROUND
  Prognosis evaluation of patients with choroidal and ciliary melanoma has experienced recent progress through tumour sampling and cytogenetic analysis of metastatic risk. By allocating tumor extension, height and linear basal diameter to defined TNM stages, an estimation of prognosis can also be made without invasive tissue sampling.
  
  
  METHODS
  Therapeutic strategies of organ preserving irradiation using different sources have clearly come to the forefront.
  
  
  RESULTS
  Due to microscopic haematogenous spreading of tumour cells prior to treatment, the metastatic risk following radiation of any form is not influenced in comparison to primary enucleation.
  
  
  CONCLUSIONS
  However, metastatic disease still remains a fatal condition which currently may only be influenced by early detection and treatment of uveal melanomas.
authors.affiliation: Campus Benjamin Franklin, Charité Augenklinik, Berlin.
authors.forename: A C
authors.initials: AC
authors.lastname: Lipski
authors.forename: N
authors.initials: N
authors.lastname: Lakotka
authors.forename: A I
authors.initials: AI
authors.lastname: Riechardt
authors.forename: G D
authors.initials: GD
authors.lastname: Willerding
authors.forename: J
authors.initials: J
authors.lastname: Heufelder
authors.forename: S
authors.initials: S
authors.lastname: Türkmen
authors.forename: U
authors.initials: U
authors.lastname: Keilholz
authors.forename: L
authors.initials: L
authors.lastname: Moser
authors.forename: A M
authors.initials: AM
authors.lastname: Joussen
mesh_terms: D002830:Choroid Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D020732:Cytogenetic Analysis / Q000379:methods; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D008545:Melanoma / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D013508:Ophthalmologic Surgical Procedures / Q000379:methods; D011878:Radiotherapy / Q000379:methods