title: An in vitro evaluation of antioxidant and colonic microbial profile levels following mushroom consumption.
abstract: The biological activity of mushroom consumption is achieved by the antioxidant effect of constituent biomolecules released during digestion. In the following study, the consumption of mushroom fungi was determined to increase the number of Lactobacillus and Bifidobacterium strains within the colon. The main phenolic antioxidant compounds identified were both gentisic and homogentisic acids. Moreover, the flavonoid catechin as well as a significant amount of δ - and γ-tocopherols was determined. The amount of Lactobacillus and Bifidobacterium strains from different sections of the human colon was significantly correlated with levels of antioxidative biomolecules. The experimental data clearly demonstrate a significant impact of mushroom consumption on the fermentative function of microorganisms in the human colon, resulting in the homeostasis of normal physiological colonic functions.
authors.affiliation: Department of Industrial Biotechnology, University of Agronomical Sciences and Veterinary Medicine Bucharest, Faculty of Biotechnology, 59 Marasti Boulevard, 011464 Bucharest, Romania.
authors.forename: Emanuel
authors.initials: E
authors.lastname: Vamanu
authors.forename: Diana
authors.initials: D
authors.lastname: Pelinescu
authors.forename: Ionela
authors.initials: I
authors.lastname: Avram
authors.forename: Sultana
authors.initials: S
authors.lastname: Nita
mesh_terms: D000363:Agaricales / Q000737:chemistry; D000975:Antioxidants / Q000008:administration & dosage* / Q000737:chemistry; D001644:Bifidobacterium / Q000187:drug effects / Q000254:growth & development; D003106:Colon / Q000382:microbiology*; D005504:Food Analysis; D006801:Humans; D007778:Lactobacillus / Q000187:drug effects / Q000254:growth & development
chemical_list: D000975:Antioxidants
references.citation: Molecules. 2011 May 25;16(6):4328-38
references.pmid: 21613974
references.citation: Evid Based Complement Alternat Med. 2012;2012:215959
references.pmid: 22454657
references.citation: Zh Mikrobiol Epidemiol Immunobiol. 2005 Jan-Feb;(1):80-2
references.pmid: 15773410
references.citation: Biomed Res Int. 2013;2013:313905
references.pmid: 23509707
references.citation: FEMS Microbiol Ecol. 2004 Dec 27;51(1):143-53
references.pmid: 16329863
references.citation: Food Chem. 2011 Sep 1;128(1):14-21
references.pmid: 25214323
references.citation: Am J Clin Nutr. 2004 Aug;80(2):245-56
references.pmid: 15277142
references.citation: Microbiology (Reading). 2002 Jan;148(Pt 1):257-266
references.pmid: 11782518
references.citation: Antiviral Res. 2011 Aug;91(2):120-32
references.pmid: 21600932
references.citation: J Nutr. 2000 Nov;130(11):2733-8
references.pmid: 11053514
references.citation: J Appl Microbiol. 2011 May;110(5):1297-306
references.pmid: 21338450
references.citation: Expert Opin Ther Targets. 2008 Mar;12(3):301-12
references.pmid: 18269340
references.citation: Appl Environ Microbiol. 2005 Oct;71(10):6150-8
references.pmid: 16204533
references.citation: Biotechnol Bioeng. 2012 Jan;109(1):74-83
references.pmid: 21809332
references.citation: Curr Opin Drug Discov Devel. 2002 Mar;5(2):194-9
references.pmid: 11926125
references.citation: Mol Nutr Food Res. 2007 Sep;51(9):1152-62
references.pmid: 17688297
references.citation: J Nutr. 2005 Jul;135(7):1726-31
references.pmid: 15987856
references.citation: Appl Environ Microbiol. 2010 Jun;76(11):3692-701
references.pmid: 20382813