title: Pharmacokinetics and applications of magnetic nanoparticles.
abstract: Nanomaterials possess enormous potential for biomedical applications, while some of the most promising nanomaterials currently under investigation demonstrate prolonged tissue retention and contain heavy metals. This article investigates the pharmacokinetics of magnetic nanoparticles (MNPs) to help identify promising candidates with optimal pharmacokinetics and clearance from the body for biomedical use and synthesize nanomaterials ideal for biomedical use. The term 'magnetic nanoparticles' (MNPs) refers to nanoparticles with ferromagnetism. Such nanoparticles have special characteristics, and many in the field of biological field have undertaken research involving, e.g., immobilized enzymes and proteins, biological cells, macromolecular separation, drug carriers, and targeted, immune, biological sensors.
authors.affiliation: State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, No.14., 3rd Sec, Ren Min Nan Road, Chengdu 610041, P.R. China. dentistcai@hotmail.com.
authors.forename: Runyi
authors.initials: R
authors.lastname: Mao
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Jiao
authors.initials: J
authors.lastname: Pei
authors.forename: Songtao
authors.initials: S
authors.lastname: Wu
authors.forename: Jie
authors.initials: J
authors.lastname: Feng
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Lin
authors.forename: Xiaoxiao
authors.initials: X
authors.lastname: Cai
mesh_terms: D000818:Animals; D006801:Humans; D060328:Magnetic Phenomena; D053768:Metal Nanoparticles; D010599:Pharmacokinetics