title: [Pap test used for detection of cellular changes associated with human papillomavirus].
abstract: Human papilloma virus can infect any mucous of the body and can cause cancer of the uterine cervix. This suggests recommending the Papanicolaou smear combined with a test for detection of human papillomavirus with a frequency interval of 3 years, since it grants greater information and fidelity to the result. The detection studies should begin at the age of 21 years and should stop at 65 years age. Until recently specific treatments did not exist to treat human papilloma virus, but recently some drugs that have demonstrated good effectiveness in curing the infection of human papilloma virus. One example is glycirrhicinic acid, which has demonstrated fewer adverse effects, as well as the possibility that its systemic employment allows treatment of lesions that are difficult to approach. The medical recommendations should be in constant revision, since a clinical trial can modify the interpretation of what is necessary to individualize each patient's treatment.
authors.affiliation: Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Distrito Federal, Mexico. mhernandezvalencia@prodigy.net.mx
authors.forename: Marcelino
authors.initials: M
authors.lastname: Hernández-Valencia
authors.forename: Adia
authors.initials: A
authors.lastname: Carrillo-Pacheco
authors.forename: Tomás
authors.initials: T
authors.lastname: Hernández-Quijano
authors.forename: Arturo
authors.initials: A
authors.lastname: Zárate
mesh_terms: D005260:Female; D006801:Humans; D065006:Papanicolaou Test; D030361:Papillomavirus Infections / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000821:virology*; D014626:Vaginal Smears
keywords: frotis vaginal; neoplasias del cuello uterino; papilloma; papiloma; uterine cervical neoplasms; vaginal smears