title: Modification of insulin sensitivity and glycemic control by activity and exercise.
abstract: Type 2 diabetes has progressed into a major contributor to preventable death, and developing optimal therapeutic strategies to prevent future type 2 diabetes and its primary clinical manifestation of cardiovascular disease is a major public health challenge. This article will provide a brief overview of the role of activity and exercise in modulating insulin sensitivity and will outline the effect of physical activity, high-intensity interval training, and resistance training on insulin sensitivity and glycemic control.
authors.affiliation: 1Exercise and Metabolic Disease Research Laboratory, Translational Sciences Section, School of Nursing, University of California, Los Angeles, CA; 2Faculty of Health and Social Development, School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, BC, CANADA; 3Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO; and 4Medicine-Division of Gastroenterology and Hepatology, University of Missouri, Columbia, MO.
authors.forename: Christian K
authors.initials: CK
authors.lastname: Roberts
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: Little
authors.forename: John P
authors.initials: JP
authors.lastname: Thyfault
mesh_terms: D001786:Blood Glucose / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000503:physiopathology* / Q000517:prevention & control; D015444:Exercise / Q000502:physiology*; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D010806:Physical Education and Training / Q000379:methods; D055070:Resistance Training
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin