title: The antimicrobial susceptibility, biofilm formation and genotypic profiles of Staphylococcus haemolyticus from bloodstream infections.
abstract: We analysed the antimicrobial susceptibility, biofilm formation and genotypic profiles of 27 isolates of Staphylococcus haemolyticus obtained from the blood of 19 patients admitted to a hospital in Rio de Janeiro, Brazil. Our analysis revealed a clinical significance of 36.8% and a multi-resistance rate of 92.6% among these isolates. All but one isolate carried the mecA gene. The staphylococcal cassette chromosome mec type I was the most prevalent mec element detected (67%). Nevertheless, the isolates showed clonal diversity based on pulsed-field gel electrophoresis analysis. The ability to form biofilms was detected in 66% of the isolates studied. Surprisingly, no icaAD genes were found among the biofilm-producing isolates.
authors.affiliation: Faculdade de Medicina, Universidade Federal Fluminense, NiteróiRJ, Brasil.
authors.forename: Patricia Vollú
authors.initials: PV
authors.lastname: Silva
authors.forename: Raquel Souza
authors.initials: RS
authors.lastname: Cruz
authors.forename: Luiz Sérgio
authors.initials: LS
authors.lastname: Keim
authors.forename: Geraldo Renato de
authors.initials: GR
authors.lastname: Paula
authors.forename: Bernadete Teixeira Ferreira
authors.initials: BT
authors.lastname: Carvalho
authors.forename: Leonardo Rocchetto
authors.initials: LR
authors.lastname: Coelho
authors.forename: Maria Cícera da Silva
authors.initials: MC
authors.lastname: Carvalho
authors.forename: Joel Mauricio Corrêa da
authors.initials: JM
authors.lastname: Rosa
authors.forename: Agnes Marie Sá
authors.initials: AM
authors.lastname: Figueiredo
authors.forename: Lenise Arneiro
authors.initials: LA
authors.lastname: Teixeira
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology; D018441:Biofilms / Q000254:growth & development*; D002648:Child; D002675:Child, Preschool; D004352:Drug Resistance, Microbial / Q000502:physiology*; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012307:Risk Factors; D041162:Staphylococcus haemolyticus / Q000187:drug effects / Q000235:genetics / Q000502:physiology; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents
references.citation: Eur J Clin Microbiol Infect Dis. 2012 Apr;31(4):605-14
references.pmid: 21822565
references.citation: PLoS One. 2011;6(5):e20191
references.pmid: 21637845
references.citation: J Med Microbiol. 2007 Oct;56(Pt 10):1328-1333
references.pmid: 17893169
references.citation: J Antimicrob Chemother. 2006 May;57(5):855-64
references.pmid: 16551694
references.citation: Eur J Clin Microbiol Infect Dis. 2011 Nov;30(11):1349-54
references.pmid: 21744039
references.citation: J Clin Microbiol. 1995 Sep;33(9):2400-4
references.pmid: 7494036
references.citation: Am J Infect Control. 2008 Jun;36(5):309-32
references.pmid: 18538699
references.citation: J Clin Microbiol. 2009 Apr;47(4):1172-80
references.pmid: 19144798
references.citation: Clin Microbiol Infect. 2007 Jul;13(7):725-7
references.pmid: 17403127
references.citation: Antimicrob Agents Chemother. 2009 Feb;53(2):531-40
references.pmid: 19064897
references.citation: Braz J Microbiol. 2011 Jan;42(1):248-55
references.pmid: 24031628
references.citation: Antimicrob Agents Chemother. 2008 Oct;52(10):3512-6
references.pmid: 18676883
references.citation: Antimicrob Agents Chemother. 2012 May;56(5):2792-3
references.pmid: 22314531
references.citation: J Clin Microbiol. 2012 Jan;50(1):166-8
references.pmid: 21976766