title: Substrate hydrolysis triggered formation of fluorescent gold nanoclusters--a new platform for the sensing of enzyme activity.
abstract: Substrate hydrolysis was utilized to trigger a "top-down" etching process for the generation of fluorescent gold nanoclusters, and the changes in emission intensity of the assay solution provide a facile way for the sensing of enzyme activity.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. China. congyu@ciac.ac.cn.
authors.forename: Yang
authors.initials: Y
authors.lastname: Chen
authors.forename: Huipeng
authors.initials: H
authors.lastname: Zhou
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Wenying
authors.initials: W
authors.lastname: Li
authors.forename: Jian
authors.initials: J
authors.lastname: Chen
authors.forename: Quan
authors.initials: Q
authors.lastname: Lin
authors.forename: Cong
authors.initials: C
authors.lastname: Yu
mesh_terms: D004789:Enzyme Activation; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism*; D005453:Fluorescence; D006046:Gold / Q000737:chemistry / Q000378:metabolism*; D006868:Hydrolysis; D053768:Metal Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D013499:Surface Properties
chemical_list: D004798:Enzymes; D006046:Gold