title: Elucidating the immunological function of the Cryptococcus neoformans capsule.
abstract: The encapsulated fungal pathogen Cryptococcus neoformans represents a significant agent of life-threatening infections in immunocompromised subjects. A unique characteristic of Cryptococcus species is the presence of a polysaccharide capsule, which is essential for virulence and endows Cryptococcus with potent immunoregulatory properties. This review provides an overview of the immunological properties of the principal components of C. neoformans capsule.
authors.affiliation: Department of Experimental Medicine, Microbiology Section, University of Perugia, Perugia, 06132, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Vecchiarelli
authors.forename: Eva
authors.initials: E
authors.lastname: Pericolini
authors.forename: Elena
authors.initials: E
authors.lastname: Gabrielli
authors.forename: Samyr
authors.initials: S
authors.lastname: Kenno
authors.forename: Stefano
authors.initials: S
authors.lastname: Perito
authors.forename: Elio
authors.initials: E
authors.lastname: Cenci
authors.forename: Claudia
authors.initials: C
authors.lastname: Monari
mesh_terms: D003455:Cryptococcus neoformans / Q000276:immunology*; D006801:Humans; D007155:Immunologic Factors; D011134:Polysaccharides / Q000276:immunology*; D037521:Virulence Factors / Q000276:immunology
chemical_list: D007155:Immunologic Factors; D011134:Polysaccharides; D037521:Virulence Factors