title: Acute Profound Thrombocytopenia after Using Abciximab for No-Reflow during Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction.
abstract: Glycoprotein IIb/IIIa antagonists are well established for their effectiveness in improving clinical outcomes in acute coronary syndrome patients undergoing percutaneous coronary intervention. Acute profound thrombocytopenia is a rare complication of abciximab. We present a case which was managed successfully for the rare complication of acute profound thrombocytopenia after using abciximab and an intra-aortic balloon pump for the treatment of a no-reflow phenomenon and consecutive cardiogenic shock during primary percutaneous coronary intervention.
authors.affiliation: Regional Cardiovascular Center, Division of Cardiology, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea.
authors.forename: Soonyoung
authors.initials: S
authors.lastname: Park
authors.forename: Jooyoung
authors.initials: J
authors.lastname: Lee
authors.forename: Sang Yeub
authors.initials: SY
authors.lastname: Lee
authors.forename: Jang-Whan
authors.initials: JW
authors.lastname: Bae
authors.forename: Kyung-Kuk
authors.initials: KK
authors.lastname: Hwang
authors.forename: Dong-Woon
authors.initials: DW
authors.lastname: Kim
authors.forename: Myeong-Chan
authors.initials: MC
authors.lastname: Cho
authors.forename: Sang Min
authors.initials: SM
authors.lastname: Kim
keywords: Abciximab; No-reflow phenomenon; Thrombocytopenia
references.citation: Am J Cardiol. 1995 Apr 15;75(12):778-82
references.pmid: 7717278
references.citation: Pharmacol Ther. 2011 Oct;132(1):72-85
references.pmid: 21664376
references.citation: Circulation. 2000 Dec 12;102(24):2923-9
references.pmid: 11113041
references.citation: Circulation. 1995 Nov 1;92(9):2373-80
references.pmid: 7586333
references.citation: Catheter Cardiovasc Interv. 2003 Oct;60(2):194-201
references.pmid: 14517924
references.citation: Lancet. 1998 Jul 11;352(9122):87-92
references.pmid: 9672272
references.citation: Circulation. 2004 May 11;109(18):2203-6
references.pmid: 15117843
references.citation: Heart. 2001 Dec;86(6):E18
references.pmid: 11711483
references.citation: Eur J Vasc Endovasc Surg. 2003 Jan;25(1):85-7
references.pmid: 12525818
references.citation: Br J Haematol. 2003 May;121(4):535-55
references.pmid: 12752095
references.citation: N Engl J Med. 1994 Apr 7;330(14):956-61
references.pmid: 8121459