title: [Assessment of the therapeutic possibilities of systemic radiotherapy as a component of combined treatment for advanced ovarian carcinoma].
abstract: The new technology of combined treatment for patients with ovarian carcinoma of III-IV stages and its relapse is presented. The essentially new component is systemic radiotherapy in nontumoricidal doses. It is used with both traditional surgical and chemotherapeutic components. Systemic radiotherapy is carried out in a form of subtotal body irradiation in two dose-time options with total dose of 1 Gy and 9 Gy. The choice of radiation option is carried out taking into account the initial somatic resource of patients estimated by the condition of lymphopoiesis. The use of systemic radiotherapy in combined treatment of advanced ovarian carcinoma allowed to achieve the significant increase of 3-, 5-year survival in patients as compared to traditional chemo-surgical method. Indirect mechanism of nontumoricidal systemic radiotherapy is to be considered as a vital way for tumor control.
authors.forename: L E
authors.initials: LE
authors.lastname: Iurkova
authors.forename: A N
authors.initials: AN
authors.lastname: Shutko
mesh_terms: D000328:Adult; D000368:Aged; D000077216:Carcinoma, Ovarian Epithelial; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D009375:Neoplasms, Glandular and Epithelial / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant; D012008:Recurrence; D012189:Retrospective Studies; D012426:Russia; D016019:Survival Analysis; D016896:Treatment Outcome; D014916:Whole-Body Irradiation / Q000009:adverse effects / Q000379:methods