title: Multiple cutaneous hemangiomas in a patient with combined pituitary hormone deficiency.
abstract: Combined pituitary hormone deficiency (CPHD) refers to a rare heterogeneous group of conditions in which there is a deficiency in at least two anterior pituitary hormones. Patients with POU1F1 mutations show a combined pituitary deficiency with low or absent levels of growth hormone, prolactin, and thyroid-stimulating hormone. In this study, a 7-month-old girl with a CPHD is presented. She had facial dysmorphologic features, hypertrichosis, and hypotonia. Additionally, she also presented with multiple cutaneous hemangioma that until now has not been reported in association with this disorder.
authors.forename: Ayca
authors.initials: A
authors.lastname: Aykut
authors.forename: Samim
authors.initials: S
authors.lastname: Ozen
authors.forename: Damla Gokşen
authors.initials: DG
authors.lastname: Sımsek
authors.forename: Huseyin
authors.initials: H
authors.lastname: Onay
authors.forename: Ozgur
authors.initials: O
authors.lastname: Cogulu
authors.forename: Sukran
authors.initials: S
authors.lastname: Darcan
authors.forename: Ferda
authors.initials: F
authors.lastname: Ozkinay
mesh_terms: D005260:Female; D006391:Hemangioma / Q000150:complications*; D006720:Homozygote; D006801:Humans; D007231:Infant, Newborn; D009154:Mutation; D010907:Pituitary Hormones / Q000172:deficiency*; D012878:Skin Neoplasms / Q000150:complications*; D050817:Transcription Factor Pit-1 / Q000235:genetics
chemical_list: C494187:POU1F1 protein, human; D010907:Pituitary Hormones; D050817:Transcription Factor Pit-1