title: Spinal neural tube defects on in utero MRI.
abstract: Spinal neural tube defects are a heterogeneous group of disorders, which remain relatively common, with a prevalence of 1-2 per 1000 live births despite advances in maternal antenatal care. They range from mild disorders with limited neurodevelopmental sequelae to extensive abnormalities with significant morbidity and mortality. The advent of in utero magnetic resonance imaging has enabled accurate anatomical characterization of an increasing number of abnormalities with increasing confidence. Recognition of the salient radiological features of these disorders and their relationship to the embryogenesis of the spinal cord and its coverings is now possible. This review describes the radiological appearances of these disorders with examples from Fetal Imaging Unit, University of Sheffield to illustrate the key anatomical and radiological features to aid the radiologist in their recognition.
authors.affiliation: Department of Neuroradiology, Royal Hallamshire Hospital, Sheffield, UK. Electronic address: fionnw1@doctors.org.uk.
authors.forename: F
authors.initials: F
authors.lastname: Williams
authors.forename: P D
authors.initials: PD
authors.lastname: Griffiths
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009436:Neural Tube Defects / Q000175:diagnosis / Q000196:embryology* / Q000473:pathology; D011296:Prenatal Diagnosis / Q000379:methods*; D013116:Spinal Cord / Q000196:embryology / Q000473:pathology