title: [The compared study in detecting the recurrence and metastases of breast cancer patients post treatment between (18)F-FDG PET/CT and conventional workup].
abstract: OBJECTIVE
  This study is to investigate the clinical role of (18)F-FDG PET/CT in detecting the recurrence and metastases of patients with breast cancer post treatment, compared to the conventional imaging technology, such as CT, MRI, and ultrasound.
  
  
  METHODS
  The reports of FDG PET/CT whole body scans and conventional imaging technology, such as CT, MRI, and ultrasound, performed from Jan to Aug 2011 on 70 patients with breast cancer post treatment were retrospectively reviewed.The accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 2 groups in detecting the recurrence and metastases were calculated and compared.
  
  
  RESULTS
  The accuracy, sensitivity, specificity, PPV and NPV of FDG PET/CT were 84.3%, 95.6%, 64.0%, 82.7% and 88.9%.The conventional imaging technology was 70.0%, 68.9%, 72.0%, 81.6% and 56.3% respectively.FDG PET/CT had altered the medical management of 20% of patients and detected 3 second primary malignancies.
  
  
  CONCLUSIONS
  FDG PET/CT is superior to conventional imaging in detecting the recurrence and metastases of patients with breast cancer post therapy.
authors.affiliation: Department of Nuclear Medicine, Sun Yat-sen University, Guangzhou, China. wanggh@sysucc.org.cn
authors.forename: Wei-guang
authors.initials: WG
authors.lastname: Zhang
authors.forename: Guo-hui
authors.initials: GH
authors.lastname: Wang
authors.forename: Wei-dong
authors.initials: WD
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Fan
authors.forename: Jian
authors.initials: J
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18