title: [Lymphangitis-associated rickettsiosis caused by Rickettsia sibirica mongolitimonae].
abstract: Rickettsia sibirica mongolitimonae was first isolated 20 years ago in Asia but has now been identified on three continents. Hyalomma spp. and Rhipicephalus pusillus ticks are vectors but only a small number of cases have been reported to date, mainly on the Mediterranean coast. This bacterium induces the lymphangitis-associated rickettsiosis, a still unfamiliar rickettsiosis that is mainly characterized by fever with a rope-like lymphangitis and/or lymphadenopathy and skin eschar occurring after tick bites. These features are especially evocative if they occur in spring. Sequellae are very rare and treatment with doxycycline is recommended.
authors.affiliation: URMITE, UM63, UMR CNRS 7278, IRD 198, Inserm U1095, faculté de médecine, Aix-Marseille université, 27, boulevard Jean-Moulin, 13385 Marseille cedex 5, France.
authors.forename: M
authors.initials: M
authors.lastname: Foissac
authors.forename: C
authors.initials: C
authors.lastname: Socolovschi
authors.forename: D
authors.initials: D
authors.lastname: Raoult
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000469:parasitology; D000835:Animals, Wild / Q000469:parasitology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017963:Azithromycin / Q000627:therapeutic use; D002478:Cells, Cultured; D000075202:Contraindications; D003937:Diagnosis, Differential; D004318:Doxycycline / Q000627:therapeutic use; D005260:Female; D005602:France / Q000453:epidemiology; D014943:Global Health; D006801:Humans; D026863:Ixodidae / Q000382:microbiology*; D008205:Lymphangitis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D008208:Lymphatic System / Q000382:microbiology; D008297:Male; D019083:Mediterranean Region / Q000453:epidemiology; D016133:Polymerase Chain Reaction / Q000379:methods; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000382:microbiology; D012281:Rickettsia / Q000145:classification / Q000302:isolation & purification* / Q000472:pathogenicity; D012282:Rickettsia Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission; D012698:Serologic Tests / Q000379:methods; D013045:Species Specificity; D064927:Tick Bites / Q000150:complications / Q000382:microbiology*; D013984:Tick Infestations / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary; D017282:Tick-Borne Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin; D004318:Doxycycline
keywords: Adenopathy; Adénopathie; Escarre d’inoculation; Eschar; Lymphangite; Lymphangitis; Rickettsia sibirica mongolitimonae; Rickettsiose; Rickettsiosis; Tick; Tique