title: A case of Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) related to rufinamide.
abstract: Drug Rash (or Reaction) with Eosinophilia and Systemic Symptoms (DRESS) is a potentially life-threatening hypersensitivity reaction to drugs characterized by rash, fever, lymphadenopathy, hematologic abnormalities, and involvement of internal organs. Initially coined in 1996, the term is used to refer to an idiosyncratic reaction to several drugs, the most common of which are carbamazepine, allopurinol, sulfasalazine, and phenobarbital. We report the first case of DRESS related to rufinamide in a ten year old boy with a history of a complex seizure disorder.
authors.affiliation: School of Medicine, University of California, Davis, Sacramento, California.
authors.forename: S
authors.initials: S
authors.lastname: Shahbaz
authors.forename: R K
authors.initials: RK
authors.lastname: Sivamani
authors.forename: T
authors.initials: T
authors.lastname: Konia
authors.forename: B
authors.initials: B
authors.lastname: Burrall
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D063926:Drug Hypersensitivity Syndrome / Q000188:drug therapy / Q000209:etiology*; D017029:Epilepsy, Complex Partial / Q000188:drug therapy; D005632:Fructose / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D000077287:Levetiracetam; D008297:Male; D010889:Piracetam / Q000031:analogs & derivatives / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D000077236:Topiramate; D014230:Triazoles / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D000927:Anticonvulsants; D014230:Triazoles; D000077236:Topiramate; D005632:Fructose; D000077287:Levetiracetam; D011241:Prednisone; C079703:rufinamide; D010889:Piracetam