title: Design of electrochemical detection of thiols based on the cleavage of the disulfide bond coupled with thionine modified gold nanoparticle-assisted amplification.
abstract: A new strategy for the electrochemical detection of thiols based on the disulfide cleavage combined with gold nanoparticle (AuNP) assisted signal amplification and an AuNP and graphene (GR) and ionic liquid (IL) modified carbon paste electrode (AuNP/GR/CILE). A superior detection limit of 0.4 pM toward glutathione could be achieved.
authors.affiliation: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China. hunxu@sohu.com.
authors.forename: Xu
authors.initials: X
authors.lastname: Hun
authors.forename: Wei
authors.initials: W
authors.lastname: Sun
authors.forename: Huanhuan
authors.initials: H
authors.lastname: Zhu
authors.forename: Feng
authors.initials: F
authors.lastname: Du
authors.forename: Fang
authors.initials: F
authors.lastname: Liu
authors.forename: Yaqiong
authors.initials: Y
authors.lastname: Xu
authors.forename: Yunhua
authors.initials: Y
authors.lastname: He
mesh_terms: D015374:Biosensing Techniques / Q000379:methods; D002244:Carbon / Q000737:chemistry; D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D005978:Glutathione / Q000032:analysis*; D006046:Gold / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry; D057230:Limit of Detection; D053758:Nanoparticles / Q000737:chemistry*; D010640:Phenothiazines / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000032:analysis*
chemical_list: D052578:Ionic Liquids; D010640:Phenothiazines; D013438:Sulfhydryl Compounds; D002244:Carbon; D006046:Gold; D006108:Graphite; D005978:Glutathione; C009469:thionine