title: 4-Nitro-phenol-piperazine (2/1).
abstract: In the title adduct, C6H5NO3·0.5C4H10N2, the piperazine ring possesses inversion symmetry and has a chair conformation. Its mean plane makes a dihedral angle of 65.45 (7)° with the 4-nitro-phenol ring. In the crystal, the piperazine ring is linked to two 4-nitro-phenol mol-ecules via O-H⋯N hydrogen bonds. The mol-ecules are also linked via bifurcated N-H⋯(O,O) hydrogen bonds involving the NO2 O atoms, forming a two-dimensional network lying parallel to (102). The networks are linked via C-H⋯O hydrogen bonds, forming a three-dimensional structure.
authors.affiliation: Department of Physics, Anna University, Chennai 600 025, India.
authors.forename: Perumal
authors.initials: P
authors.lastname: Nagapandiselvi
authors.forename: Srinivasan
authors.initials: S
authors.lastname: Muralidharan
authors.forename: Thothadri
authors.initials: T
authors.lastname: Srinivasan
authors.forename: Rengaswamy
authors.initials: R
authors.lastname: Goplalakrishnan
authors.forename: Devadasan
authors.initials: D
authors.lastname: Velmurugan
references.citation: J Med Chem. 2008 Apr 24;51(8):2457-67
references.pmid: 18357976
references.citation: J Med Chem. 2006 Jun 1;49(11):3116-35
references.pmid: 16722631
references.citation: Eur J Med Chem. 2009 Mar;44(3):1363-8
references.pmid: 18514971
references.citation: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references.pmid: 18156677
references.citation: Bioorg Med Chem. 2006 Oct 1;14(19):6539-47
references.pmid: 16806947
references.citation: Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55
references.pmid: 19171970
references.citation: Bioorg Med Chem. 2004 May 1;12(9):2225-38
references.pmid: 15080922
references.citation: Eur J Med Chem. 2007 Jul;42(7):985-92
references.pmid: 17316916