title: Potential of fluid-attenuated inversion recovery MRI as an alternative to contrast-enhanced MRI for oral and maxillofacial vascular malformations: experimental and clinical studies.
abstract: OBJECTIVE
  To determine the potential of fluid-attenuated inversion recovery (FLAIR) imaging of oral and maxillofacial vascular malformations as an alternative to contrast-enhanced magnetic resonance imaging (MRI), we investigated the influence of differences in T1 and T2 values on image contrast in FLAIR images and evaluated the diagnostic utility of such images.
  
  
  METHODS
  FLAIR imaging and heavily T2-weighted (hT2-weighted) imaging were performed using a phantom. FLAIR and hT2-weighted images of 32 lesions (11 mucous cysts, 12 vascular malformations, and 9 tumors) were also studied retrospectively. The contrast-to-noise ratios (CNRs) and CNR change ratios were compared.
  
  
  RESULTS
  All aqueous solutions except those with a short T2 value were discriminated by CNR change ratio (P < .05). All 3 types of lesions were discriminated by CNR change ratio (P < .05).
  
  
  CONCLUSIONS
  FLAIR imaging has potential as an alternative to contrast-enhanced MRI in differentiating vascular malformations from other types of lesions in the oral and maxillofacial region.
authors.affiliation: PhD Student, Department of Oral and Maxillofacial Radiology, Tokyo Dental College, Chiba, Japan. Electronic address: sasakiyoshinori@tdc.ac.jp.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Sasaki
authors.forename: Junichiro
authors.initials: J
authors.lastname: Sakamoto
authors.forename: Mika
authors.initials: M
authors.lastname: Otonari-Yamamoto
authors.forename: Keiichi
authors.initials: K
authors.lastname: Nishikawa
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Sano
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002648:Child; D003287:Contrast Media; D005145:Face / Q000473:pathology*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008437:Maxilla / Q000473:pathology*; D008875:Middle Aged; D009055:Mouth / Q000473:pathology*; D019047:Phantoms, Imaging; D054079:Vascular Malformations / Q000175:diagnosis*
chemical_list: D003287:Contrast Media