title: The effect of solar-geomagnetic activity during and after admission on survival in patients with acute coronary syndromes.
abstract: A number of studies have established the effects of solar-geomagnetic activity on the human cardio-vascular system. It is plausible that the heliophysical conditions existing during and after hospital admission may affect survival in patients with acute coronary syndromes (ACS). We analyzed data from 1,413 ACS patients who were admitted to the Hospital of Kaunas University of Medicine, Lithuania, and who survived for more than 4 days. We evaluated the associations between active-stormy geomagnetic activity (GMA), solar proton events (SPE), and solar flares (SF) that occurred 0-3 days before and after admission, and 2-year survival, based on Cox's proportional-hazards model, controlling for clinical data. After adjustment for clinical variables, active-stormy GMA on the 2nd day after admission was associated with an increased (by 1.58 times) hazard ratio (HR) of cardiovascular death (HR=1.58, 95 % CI 1.07-2.32). For women, geomagnetic storm (GS) 2 days after SPE occurred 1 day after admission increased the HR by 3.91 times (HR=3.91, 95 % CI 1.31-11.7); active-stormy GMA during the 2nd-3rd day after admission increased the HR by over 2.5 times (HR=2.66, 95 % CI 1.40-5.03). In patients aged over 70 years, GS occurring 1 day before or 2 days after admission, increased the HR by 2.5 times, compared to quiet days; GS in conjunction with SF on the previous day, nearly tripled the HR (HR=3.08, 95 % CI 1.32-7.20). These findings suggest that the heliophysical conditions before or after the admission affect the hazard ratio of lethal outcome; adjusting for clinical variables, these effects were stronger for women and older patients.
authors.affiliation: Institute of Cardiology, Vytautas Magnus University, K. Donelaičio g. 58, 44248, Kaunas, Lithuania, j.vencloviene@gmf.vdu.lt.
authors.forename: Jone
authors.initials: J
authors.lastname: Vencloviene
authors.forename: Ruta
authors.initials: R
authors.lastname: Babarskiene
authors.forename: Irena
authors.initials: I
authors.lastname: Milvidaite
authors.forename: Raimondas
authors.initials: R
authors.lastname: Kubilius
authors.forename: Jolanta
authors.initials: J
authors.lastname: Stasionyte
mesh_terms: D054058:Acute Coronary Syndrome / Q000401:mortality*; D000368:Aged; D000789:Angina, Unstable / Q000401:mortality*; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D053208:Kaplan-Meier Estimate; D008097:Lithuania / Q000453:epidemiology; D060328:Magnetic Phenomena; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality*; D019445:Solar Activity
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