title: Acute post-streptococcal glomerulonephritis with acute kidney injury in nephrotic syndrome with the glomerular deposition of nephritis-associated plasmin receptor antigen.
abstract: We herein report the case of a 17-year-old man who developed an increased plasma creatinine level (11.1 mg/dL) and oliguria with massive proteinuria (27.3 g/day) four weeks after an abraded wound to his right knee. The histology of the renal biopsy specimens showed diffuse endocapillary proliferative glomerulonephritis with the deposition of nephritis-associated plasmin receptor in the glomerulus. A case of acute kidney injury due to nephrotic syndrome caused by acute post-streptococcal glomerulonephritis was diagnosed. His renal function and proteinuria were improved with supportive care, including hemodialysis, without the administration of immunosuppressive agents.
authors.affiliation: Division of Rheumatology and Clinical Immunology, Jichi Medical University, Japan.
authors.forename: Ayako
authors.initials: A
authors.lastname: Kokuzawa
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Morishita
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Yoshizawa
authors.forename: Kana
authors.initials: K
authors.lastname: Iwazu
authors.forename: Takanori
authors.initials: T
authors.lastname: Komada
authors.forename: Tetsu
authors.initials: T
authors.lastname: Akimoto
authors.forename: Osamu
authors.initials: O
authors.lastname: Saito
authors.forename: Takashi
authors.initials: T
authors.lastname: Oda
authors.forename: Fumi
authors.initials: F
authors.lastname: Takemoto
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ando
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Muto
authors.forename: Wako
authors.initials: W
authors.lastname: Yumura
authors.forename: Eiji
authors.initials: E
authors.lastname: Kusano
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D000293:Adolescent; D000942:Antigens, Bacterial / Q000378:metabolism*; D005921:Glomerulonephritis / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D006801:Humans; D007678:Kidney Glomerulus / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D008297:Male; D009404:Nephrotic Syndrome / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D011956:Receptors, Cell Surface / Q000378:metabolism*; D013290:Streptococcal Infections / Q000150:complications* / Q000276:immunology / Q000382:microbiology
chemical_list: D000942:Antigens, Bacterial; D011956:Receptors, Cell Surface; C517776:nephritis-associated plasminogen receptor, Streptococcus