title: Intrinsic activity of odorant receptors guides sensory map formation.
abstract: Olfactory sensory neurons innervate the olfactory bulb in stereotyped patterns according to the odorant receptors they express. A study by Nakashima et al. in this issue demonstrates that the odorant receptor's level of intrinsic activity-in the absence of activating odorant-influences the guidance of olfactory axons to their targets.
authors.affiliation: Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute and QB3 Functional Genomics Laboratory, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: jngai@berkeley.edu.
authors.forename: John
authors.initials: J
authors.lastname: Ngai
mesh_terms: D000818:Animals; D001369:Axons / Q000378:metabolism*; D009833:Olfactory Pathways / Q000196:embryology*; D018035:Receptors, Odorant / Q000378:metabolism*; D011984:Sensory Receptor Cells / Q000378:metabolism*
chemical_list: D018035:Receptors, Odorant
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