title: Distinct neural circuits subserve interpersonal and non-interpersonal emotions.
abstract: Emotions elicited by interpersonal versus non-interpersonal experiences have different effects on neurobiological functioning in both animals and humans. However, the extent to which the brain circuits underlying interpersonal and non-interpersonal emotions are distinct still remains unclear. The goal of our study was to assess whether different neural circuits are implicated in the processing of arousal and valence of interpersonal versus non-interpersonal emotions. During functional magnetic resonance imaging, participants imagined themselves in emotion-eliciting interpersonal or non-interpersonal situations and then rated the arousal and valence of emotions they experienced. We identified (1) separate neural circuits that are implicated in the arousal and valence dimensions of interpersonal versus non-interpersonal emotions, (2) circuits that are implicated in arousal and valence for both types of emotion, and (3) circuits that are responsive to the type of emotion, regardless of the valence or arousal level of the emotion. We found extensive recruitment of limbic (for arousal) and temporal-parietal (for valence) systems associated with processing of specifically interpersonal emotions compared to non-interpersonal ones. The neural bases of interpersonal and non-interpersonal emotions may, therefore, be largely distinct.
authors.affiliation: a Division of Developmental Neuroscience, Department of Psychiatry , Columbia University College of Physicians and Surgeons, and New York State Psychiatric Institute , New York , NY , USA.
authors.forename: Alla
authors.initials: A
authors.lastname: Landa
authors.forename: Zhishun
authors.initials: Z
authors.lastname: Wang
authors.forename: James A
authors.initials: JA
authors.lastname: Russell
authors.forename: Jonathan
authors.initials: J
authors.lastname: Posner
authors.forename: Yunsuo
authors.initials: Y
authors.lastname: Duan
authors.forename: Alayar
authors.initials: A
authors.lastname: Kangarlu
authors.forename: Yuankai
authors.initials: Y
authors.lastname: Huo
authors.forename: Brian A
authors.initials: BA
authors.lastname: Fallon
authors.forename: Bradley S
authors.initials: BS
authors.lastname: Peterson
mesh_terms: D000328:Adult; D001143:Arousal; D001921:Brain / Q000098:blood supply / Q000502:physiology*; D001931:Brain Mapping; D004644:Emotions / Q000502:physiology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007398:Interpersonal Relations; D008279:Magnetic Resonance Imaging; D008297:Male; D009415:Nerve Net / Q000098:blood supply / Q000502:physiology*; D010100:Oxygen; D010775:Photic Stimulation; D012919:Social Behavior; D055815:Young Adult
chemical_list: D010100:Oxygen
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