title: Diphtheria Antibodies and T lymphocyte Counts in Patients Infected With HIV-1.
abstract: We assessed the IgG levels anti-diphtheria (D-Ab) and T cell counts (CD4+ and CD8+) in HIV-1 infected subjects undergoing or not highly active antiretroviral therapy (HAART). Approximately 70% of all HIV-1 patients were unprotected against diphtheria. There were no differences in D-Ab according to CD4 counts. Untreated patients had higher D-Ab (geometric mean of 0.62 IU/ml) than HAART-patients (geometric mean of 0.39 IU/ml). The data indicated the necessity of keeping all HIV-1 patients up-to-date with their vaccination.
authors.affiliation: Instituto de Biologia do Exército , Rio de Janeiro, RJ , Brasil ; Universidade do Estado do Rio de Janeiro, Faculdade de Ciências Médicas, Departamento de Microbiologia, Imunologia e Parasitologia , Rio de Janeiro, RJ , Brasil.
authors.forename: Francisco A B
authors.initials: FA
authors.lastname: Speranza
authors.forename: Solange K
authors.initials: SK
authors.lastname: Ishii
authors.forename: Luiz C S
authors.initials: LC
authors.lastname: Thuler
authors.forename: Paulo V
authors.initials: PV
authors.lastname: Damasco
authors.forename: Raphael
authors.initials: R
authors.lastname: Hirata
authors.forename: Ana L
authors.initials: AL
authors.lastname: Mattos-Guaraldi
authors.forename: Lucimar G
authors.initials: LG
authors.lastname: Milagres
keywords: HIV-1; antibody to diphtheria toxin; vaccination
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