title: Stable isotope dilution mass spectrometry for membrane transporter quantitation.
abstract: This review provides an introduction to stable isotope dilution mass spectrometry (MS) and its emerging applications in the analysis of membrane transporter proteins. Various approaches and application examples, for the generation and use of quantitation reference standards—either stable isotope-labeled peptides or proteins—are discussed as they apply to the MS quantitation of membrane proteins. Technological considerations for the sample preparation of membrane transporter proteins are also presented.
authors.forename: Vahid
authors.initials: V
authors.lastname: Farrokhi
authors.forename: Adam J
authors.initials: AJ
authors.lastname: McShane
authors.forename: Reza
authors.initials: R
authors.lastname: Nemati
authors.forename: Xudong
authors.initials: X
authors.lastname: Yao
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000737:chemistry; D006801:Humans; D007553:Isotope Labeling / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D026901:Membrane Transport Proteins / Q000032:analysis*
chemical_list: D026901:Membrane Transport Proteins
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