title: Design and implementation of a film dosimetry audit tool for comparison of planned and delivered dose distributions in high dose rate (HDR) brachytherapy.
abstract: A novel phantom is presented for 'full system' dosimetric audit comparing planned and delivered dose distributions in HDR gynaecological brachytherapy, using clinical treatment applicators. The brachytherapy applicator dosimetry test object consists of a near full-scatter water tank with applicator and film supports constructed of Solid Water, accommodating any typical cervix applicator. Film dosimeters are precisely held in four orthogonal planes bisecting the intrauterine tube, sampling dose distributions in the high risk clinical target volume, points A and B, bladder, rectum and sigmoid. The applicator position is fixed prior to CT scanning and through treatment planning and irradiation. The CT data is acquired with the applicator in a near clinical orientation to include applicator reconstruction in the system test. Gamma analysis is used to compare treatment planning system exported RTDose grid with measured multi-channel film dose maps. Results from two pilot audits are presented, using Ir-192 and Co-60 HDR sources, with a mean gamma passing rate of 98.6% using criteria of 3% local normalization and 3 mm distance to agreement (DTA). The mean DTA between prescribed dose and measured film dose at point A was 1.2 mm. The phantom was funded by IPEM and will be used for a UK national brachytherapy dosimetry audit.
authors.affiliation: Department of Physics, Faculty of Engineering and Physical Science, University of Surrey, GU2 7JP, UK. Medical Physics Department, F-Level, Queen Alexandra Hospital, Portsmouth Hospitals NHS Trust, Portsmouth, PO6 3LY, UK.
authors.forename: Antony L
authors.initials: AL
authors.lastname: Palmer
authors.forename: Chris
authors.initials: C
authors.lastname: Lee
authors.forename: Ailsa J
authors.initials: AJ
authors.lastname: Ratcliffe
authors.forename: David
authors.initials: D
authors.lastname: Bradley
authors.forename: Andrew
authors.initials: A
authors.lastname: Nisbet
mesh_terms: D001918:Brachytherapy / Q000592:standards*; D054869:Clinical Audit / Q000379:methods*; D005373:Film Dosimetry / Q000295:instrumentation / Q000592:standards*; D006801:Humans; D019047:Phantoms, Imaging; D010865:Pilot Projects; D011829:Radiation Dosage; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D015203:Reproducibility of Results; D035501:Uncertainty