title: An efficient synthesis of polysubstituted pyrroles via copper-catalyzed coupling of oxime acetates with dialkyl acetylenedicarboxylates under aerobic conditions.
abstract: A Cu-catalyzed [3+2]-type condensation reaction of oxime acetates and dialkyl acetylenedicarboxylates that provides highly substituted pyrroles under aerobic conditions is described. The newly formed pyrroles are easily employed for further transformations to prepare pyrrolo[2,1-a]isoquinoline skeletons.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China. jianghf@scut.edu.cn.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Tang
authors.forename: Liangbin
authors.initials: L
authors.lastname: Huang
authors.forename: Chaorong
authors.initials: C
authors.lastname: Qi
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
mesh_terms: D000085:Acetates / Q000737:chemistry*; D000114:Acetylene / Q000031:analogs & derivatives*; D002264:Carboxylic Acids / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007546:Isoquinolines / Q000138:chemical synthesis / Q000737:chemistry; D010091:Oximes / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000085:Acetates; D002264:Carboxylic Acids; D007546:Isoquinolines; D010091:Oximes; D011758:Pyrroles; D003300:Copper; C039109:isoquinoline; D000114:Acetylene