title: Presentation and management of trapped neutrophil syndrome (TNS) in UK Border collies.
abstract: Three UK bred Border collie puppies were presented for investigation of pyrexia and severe lameness with associated joint swelling. Investigations revealed neutropenia, radiographic findings suggesting metaphyseal osteopathy, and polyarthritis and all dogs were subsequently confirmed with trapped neutrophil syndrome. Clinical improvement was seen after treatment with prednisolone and antibiotics and the dogs all survived to adulthood with a good short- to medium-term outcome. Trapped neutrophil syndrome is an important differential diagnosis for young Border collie dogs in the UK presenting with pyrexia, neutropenia and musculoskeletal signs.
authors.affiliation: School of Veterinary Science, University of Liverpool, Neston, CH64 7TE.
authors.forename: S L
authors.initials: SL
authors.lastname: Mason
authors.forename: R
authors.initials: R
authors.lastname: Jepson
authors.forename: M
authors.initials: M
authors.lastname: Maltman
authors.forename: D J
authors.initials: DJ
authors.lastname: Batchelor
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001168:Arthritis / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics / Q000662:veterinary; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D004285:Dogs; D005260:Female; D005334:Fever / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics / Q000662:veterinary; D007958:Leukocyte Count / Q000662:veterinary; D008297:Male; D009503:Neutropenia / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D009504:Neutrophils; D011239:Prednisolone / Q000627:therapeutic use; D013577:Syndrome; D006113:United Kingdom
chemical_list: D000900:Anti-Bacterial Agents; D011239:Prednisolone