title: Effects of electroacupuncture and Chinese kidney-nourishing medicine on polycystic ovary syndrome in obese patients.
abstract: OBJECTIVE
  To explore the effect of electroacupuncture and Chinese kidney-nourishing medicine on insulin (INS), adiponectin (APN), leptin (LEP), and glucolipid metabolism of obese patients with polycystic ovary syndrome (PCOS).
  
  
  METHODS
  Sixty-seven obese PCOS patients were randomly divided into two groups. Thirty-three patients in the acupuncture-medicine group were treated three times a week with electroacupuncture at the Tianshu (ST 25), Zhongwan (CV 12), Qi-hai (CV 6), Sanyinjiao (SP 6), Geshu (BL 17), and Ciliao (BL 32) acupoints. They also took the Chinese drug, Tiankui capsule, for 3 months as a course of treatment. Point-taking and treatment in the electroacupuncture group of 34 patients was the same as those in the acupuncture-medicine group. We observed and compared the changes in the obesity-related indexes of body weight (BW), body mass index (BMI), and waist-hip ratio (WHR), as well as fasting plasma glucose (FPG), fasting insulin (FINS), APN, and LEP.
  
  
  RESULTS
  BW, BMI, WHR, and FINS decreased and insulin sensitivity index (ISI) and APN were higher in the acupuncture-medicine group than in the electroacupuncture group (P < 0.01). There was no obvious difference in LEP between the two groups (P > 0.05).
  
  
  CONCLUSIONS
  Acupuncture combined with medicine is better than just electroacupuncture for obese PCOS patients by improving obesity-related indexes, insulin sensitivity, and APN level. This indicates that acupuncture-medicine therapy is worth clinical popularization.
authors.affiliation: Department of Acupuncture and Moxibustion, Shanghai Tianshan Hospital of Traditional Chinese Medicine, Shanghai 200051, China.
authors.forename: Liqing
authors.initials: L
authors.lastname: Yu
authors.forename: Yanjun
authors.initials: Y
authors.lastname: Liao
authors.forename: Huangan
authors.initials: H
authors.lastname: Wu
authors.forename: Jimeng
authors.initials: J
authors.lastname: Zhao
authors.forename: Luyi
authors.initials: L
authors.lastname: Wu
authors.forename: Yin
authors.initials: Y
authors.lastname: Shi
authors.forename: Jianqiao
authors.initials: J
authors.lastname: Fang
mesh_terms: D052242:Adiponectin / Q000378:metabolism; D000293:Adolescent; D000328:Adult; D001835:Body Weight; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D015671:Electroacupuncture; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007333:Insulin Resistance; D020738:Leptin / Q000378:metabolism; D009765:Obesity / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D011085:Polycystic Ovary Syndrome / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D049629:Waist-Hip Ratio; D055815:Young Adult
chemical_list: D052242:Adiponectin; D004365:Drugs, Chinese Herbal; D020738:Leptin; D005947:Glucose