title: Secondary signet ring cell carcinoma of prostate.
abstract: True metastases to prostate from solid tumors are reported only in 0.2% of all surgical prostatic specimens and 2.9% of all male postmortems. Clinical context, morphological features, and immunohistochemical localization of prostate specific antigen (PSA) are supposed to clarify the differential diagnosis between a secondary and a primary tumor. We report an unusual and rare case of secondary signet ring cell carcinoma (SRCC) of prostate in which the clinical data and signet ring cell morphology pointed toward the diagnosis of a primary SRCC. Immunohistochemistry (IHC) for PSA not only proved the case to be a secondary SRCC but also initiated the process for diagnosis of the occult primary malignancy in the patient's stomach.
authors.affiliation: Department of Pathology, North Bengal Medical College, Sushruta Nagar, Darjeeling, India.
authors.forename: Kalyan
authors.initials: K
authors.lastname: Khan
authors.forename: Arghya
authors.initials: A
authors.lastname: Bandyopadhyay
authors.forename: Mimi
authors.initials: M
authors.lastname: Gangopadhyay
authors.forename: Subrata
authors.initials: S
authors.lastname: Chakraborty
authors.forename: Pranati
authors.initials: P
authors.lastname: Bera
keywords: Prostate specific antigen; prostate; signet ring cell carcinoma
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