title: Antibacterial, antiurease, and antioxidant activities of some arylidene barbiturates.
abstract: Some series of arylidene barbiturates and thiobarbiturates were evaluated for their antibacterial, antioxidant, and urease inhibition activities. The arylidene barbiturates and thiobarbiturates were tested for antimicrobial activity using the agar well diffusion technique against 13 bacteria. The synthesized compounds (1a-g) were screened for antiurease and antioxidant activities. The results showed that the synthesized compounds (1a-g) had effective antiurease, antioxidant, and antibacterial activities.
authors.affiliation: Department of Chemistry, Faculty of Arts and Sciences, Giresun University, 28049, Giresun, Turkey, baharsokmen@yahoo.com.
authors.forename: Bahar Bilgin
authors.initials: BB
authors.lastname: Sokmen
authors.forename: Serpil
authors.initials: S
authors.lastname: Ugras
authors.forename: Hasan Yucel
authors.initials: HY
authors.lastname: Sarikaya
authors.forename: Halil Ibrahim
authors.initials: HI
authors.lastname: Ugras
authors.forename: Refiye
authors.initials: R
authors.lastname: Yanardag
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000975:Antioxidants / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001463:Barbiturates / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010084:Oxidation-Reduction / Q000187:drug effects; D013858:Thiobarbiturates / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D014510:Urease / Q000037:antagonists & inhibitors
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D001463:Barbiturates; D013858:Thiobarbiturates; D014510:Urease
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