title: Natural history of Bartonella-infecting rodents in light of new knowledge on genomics, diversity and evolution.
abstract: Among the 33 confirmed Bartonella species to date, more than half are hosted by rodent species, and at least five of them have been involved in human illness causing diverse symptoms including fever, myocarditis, endocarditis, lymphadenitis and hepatitis. In almost all countries, wild rodents are infected by extremely diverse Bartonella strains with a high prevalence. In the present paper, in light of new knowledge on rodent-adapted Bartonella species genomics, we bring together knowledge gained in recent years to have an overview of the impact of rodent-adapted Bartonella infection on humans and to determine how diversity of Bartonella helps to understand their mechanisms of adaptation to rodents and the consequences on human health.
authors.affiliation: USC Bipar, Bartonella et Tiques, INRA, Anses, 23 Avenue du Général de Gaulle, 94 700 Maisons-Alfort, France.
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Buffet
authors.forename: Michael
authors.initials: M
authors.lastname: Kosoy
authors.forename: Muriel
authors.initials: M
authors.lastname: Vayssier-Taussat
mesh_terms: D000220:Adaptation, Biological; D000818:Animals; D001473:Bartonella / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D001474:Bartonella Infections / Q000382:microbiology* / Q000662:veterinary*; D019143:Evolution, Molecular; D014644:Genetic Variation; D016680:Genome, Bacterial; D006801:Humans; D012376:Rodent Diseases / Q000382:microbiology*; D012377:Rodentia