title: Microneedle electrodes toward an amperometric glucose-sensing smart patch.
abstract: Here, efforts toward the development of a microneedle-based glucose sensor or "smart patch" for intradermal glucose sensing are described. Metallic microneedle array electrodes, conducting polymers, and glucose oxidase form the sensor platform. This work represents the first steps toward the development of painless, transdermal-sensing devices for continuous glucose monitoring.
authors.affiliation: The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA, 02142, USA; Department of Anesthesiology, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA, 02115, USA.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Invernale
authors.forename: Benjamin C
authors.initials: BC
authors.lastname: Tang
authors.forename: Royce L
authors.initials: RL
authors.lastname: York
authors.forename: Long
authors.initials: L
authors.lastname: Le
authors.forename: David Yupeng
authors.initials: DY
authors.lastname: Hou
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Anderson
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D004566:Electrodes; D004867:Equipment Design; D005947:Glucose / Q000032:analysis*; D005949:Glucose Oxidase / Q000737:chemistry; D006801:Humans; D009339:Needles; D011108:Polymers / Q000737:chemistry; D057968:Transdermal Patch
chemical_list: D011108:Polymers; D005949:Glucose Oxidase; D005947:Glucose
keywords: conducting polymers; glucose oxidase; glucose sensors; microneedles