title: Kawasaki disease: part I. Diagnosis, clinical features, and pathogenesis.
abstract: Kawasaki disease, or mucocutaneous lymph node syndrome, most commonly affects children between 6 months and 5 years of age. Approximately 90% of patients have mucocutaneous manifestations. This article will focus on the epidemiology of Kawasaki disease in the United States as it relates to other countries, the diagnosis of Kawasaki disease, its clinical course, and the currently accepted theories of pathogenesis. A particular focus is given to the various dermatologic manifestations that may occur.
authors.affiliation: Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Bayers
authors.forename: Stanford T
authors.initials: ST
authors.lastname: Shulman
authors.forename: Amy S
authors.initials: AS
authors.lastname: Paller
mesh_terms: D017677:Age Distribution; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D002675:Child, Preschool; D004502:Education, Medical, Continuing; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index; D017678:Sex Distribution; D014481:United States / Q000453:epidemiology
chemical_list: D016756:Immunoglobulins, Intravenous
keywords: AHA; ALT; American Heart Association; BCG; C-reactive protein; CRP; ESR; IVIG; KD; Kawasaki disease; WBC; alanine aminotransferase; bacillus Calmette–Guérin; diagnosis; epidemiology; erythrocyte sedimentation rate; intravenous immunoglobulin; mucocutaneous lymph node syndrome; pathogenesis; pediatric; vasculitis; white blood cell