title: Rhodium catalyzed cyanation of chelation assisted C-H bonds.
abstract: A rhodium-catalyzed cyanation of chelation assisted C-H bonds is described employing N-cyano-N-phenyl-p-methylbenzenesulfonamide as an efficient cyanating reagent. The present method allowed the synthesis of various benzonitirle derivatives in good to excellent yield. A number of chelating groups are also effective in the present cyanation of C-H bonds. In addition, the developed methodology was applied in the formal synthesis of the isoquinoline alkaloid, menisporphine.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Madras , Chennai-600036, India.
authors.forename: Manthena
authors.initials: M
authors.lastname: Chaitanya
authors.forename: Dongari
authors.initials: D
authors.lastname: Yadagiri
authors.forename: Pazhamalai
authors.initials: P
authors.lastname: Anbarasan
mesh_terms: D002384:Catalysis; D002614:Chelating Agents / Q000737:chemistry*; D006860:Hydrogen Bonding; D007202:Indicators and Reagents / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*
chemical_list: D002614:Chelating Agents; D007202:Indicators and Reagents; D009570:Nitriles; D012238:Rhodium