title: Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma.
authors.affiliation: Netherlands Cancer Institute, Amsterdam, the Netherlands.
authors.forename: Nienke
authors.initials: N
authors.lastname: van Rooij
authors.forename: Marit M
authors.initials: MM
authors.lastname: van Buuren
authors.forename: Daisy
authors.initials: D
authors.lastname: Philips
authors.forename: Arno
authors.initials: A
authors.lastname: Velds
authors.forename: Mireille
authors.initials: M
authors.lastname: Toebes
authors.forename: Bianca
authors.initials: B
authors.lastname: Heemskerk
authors.forename: Laura J A
authors.initials: LJ
authors.lastname: van Dijk
authors.forename: Sam
authors.initials: S
authors.lastname: Behjati
authors.forename: Henk
authors.initials: H
authors.lastname: Hilkmann
authors.forename: Dris
authors.initials: D
authors.lastname: El Atmioui
authors.forename: Marja
authors.initials: M
authors.lastname: Nieuwland
authors.forename: Michael R
authors.initials: MR
authors.lastname: Stratton
authors.forename: Ron M
authors.initials: RM
authors.lastname: Kerkhoven
authors.forename: Can
authors.initials: C
authors.lastname: Kesmir
authors.forename: John B
authors.initials: JB
authors.lastname: Haanen
authors.forename: Pia
authors.initials: P
authors.lastname: Kvistborg
authors.forename: Ton N
authors.initials: TN
authors.lastname: Schumacher
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D000951:Antigens, Neoplasm / Q000276:immunology*; D000970:Antineoplastic Agents / Q000627:therapeutic use; D004273:DNA, Neoplasm / Q000032:analysis; D059472:Exome / Q000235:genetics; D006801:Humans; D000074324:Ipilimumab; D016246:Lymphocytes, Tumor-Infiltrating / Q000276:immunology*; D008297:Male; D008545:Melanoma / Q000188:drug therapy / Q000235:genetics* / Q000276:immunology; D008875:Middle Aged; D012878:Skin Neoplasms / Q000188:drug therapy / Q000235:genetics* / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D000970:Antineoplastic Agents; D004273:DNA, Neoplasm; D000074324:Ipilimumab
references.citation: Nat Methods. 2009 Jul;6(7):520-6
references.pmid: 19543285
references.citation: N Engl J Med. 2010 Aug 19;363(8):711-23
references.pmid: 20525992
references.citation: Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W509-12
references.pmid: 18463140
references.citation: N Engl J Med. 2012 Jun 28;366(26):2443-54
references.pmid: 22658127
references.citation: EMBO J. 2013 Jan 23;32(2):194-203
references.pmid: 23258224
references.citation: Nat Med. 2006 Feb;12(2):246-51
references.pmid: 16462803
references.citation: Oncoimmunology. 2012 Aug 1;1(5):579-580
references.pmid: 22934249
references.citation: Nat Protoc. 2012 Apr 12;7(5):891-902
references.pmid: 22498709
references.citation: Nat Med. 2013 Jun;19(6):747-52
references.pmid: 23644516
references.citation: Bioinformatics. 2004 Jun 12;20(9):1388-97
references.pmid: 14962912
references.citation: Cancer Res. 2008 Feb 1;68(3):889-92
references.pmid: 18245491
references.citation: Nat Genet. 2011 May;43(5):442-6
references.pmid: 21499247
references.citation: Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16723-8
references.pmid: 21933959
references.citation: Nat Genet. 2012 Sep;44(9):1006-14
references.pmid: 22842228
references.citation: Oncoimmunology. 2012 Jul 1;1(4):409-418
references.pmid: 22754759
references.citation: Nat Rev Mol Cell Biol. 2008 Aug;9(8):616-27
references.pmid: 18594563
references.citation: Nat Protoc. 2006;1(3):1120-32
references.pmid: 17406393
references.citation: N Engl J Med. 2012 Jun 28;366(26):2455-65
references.pmid: 22658128
references.citation: Immunogenetics. 2005 Apr;57(1-2):33-41
references.pmid: 15744535
references.citation: Nature. 2012 Feb 08;482(7385):400-4
references.pmid: 22318521
references.citation: Cell. 2012 Jul 20;150(2):251-63
references.pmid: 22817889
references.citation: Cancer Res. 2012 Mar 1;72(5):1081-91
references.pmid: 22237626