title: Robotic radical hysterectomy following neoadjuvant chemotherapy in FIGO stage IIIB cervical cancer: a case report.
abstract: BACKGROUND
  The management of advanced cervical cancer is challenging. The administration of neoadjuvant chemotherapy (NACT) followed by radical hysterectomy has proved to be safe in selected cases. Nevertheless, data on the use of minimally invasive surgery is lacking with this clinical application.
  
  
  METHODS
  A 31 year-old woman was diagnosed with a FIGO stage IIIB squamous cell cervical carcinoma. During multidisciplinary consultation it was decided that she should receive NACT, followed by robotic hysterectomy.
  
  
  RESULTS
  After three cycles of TIP (paclitaxel, ifosfamide and cisplatin), the patient achieved a complete clinical and radiological response. She underwent robotic type III/C2 radical hysterectomy with bilateral salpingo-oophorectomy and bilateral systematic pelvic lymphadenectomy. No complications were recorded. The complete response was confirmed at pathological examination. Two additional cycles of adjuvant chemotherapy were administered, and the patient is currently without evidence of disease at 18 months of follow-up.
  
  
  CONCLUSIONS
  In selected patients, robotics is a viable option to accomplish radical hysterectomy, including cases of advanced cervical cancer. Further experiences are needed to confirm our findings.
authors.affiliation: Department of Gynaecology, IRCCS, Humanitas Clinical and Research Centre, Rozzano, Milan, Italy.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Siesto
authors.forename: Domenico
authors.initials: D
authors.lastname: Vitobello
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000295:instrumentation / Q000379:methods*; D007069:Ifosfamide / Q000008:administration & dosage; D008197:Lymph Node Excision / Q000379:methods; D020360:Neoadjuvant Therapy; D017239:Paclitaxel / Q000008:administration & dosage; D012371:Robotics / Q000379:methods*; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000601:surgery*
chemical_list: D017239:Paclitaxel; D002945:Cisplatin; D007069:Ifosfamide
keywords: cervical carcinoma; neoadjuvant chemotherapy; pelvic lymphadenectomy; robot-assisted laparoscopy; robotic surgery