title: Macular ganglion cell complex thickness in glaucoma with superior or inferior visual hemifield defects.
abstract: OBJECTIVE
  To elucidate the relationship between the macular ganglion cell complex thickness (GCCT) and its corresponding superior or inferior visual hemifield defects, and the apparently normal visual hemifield, and to explore the relationship between the macular GCCT of the corresponding apparently normal hemifield and the severity of the glaucomatous visual field defects in the same eye.
  
  
  METHODS
  Sixty-seven eyes of 67 patients with open-angle glaucoma showed superior or inferior hemifield defects. We measured the visual field using the Humphrey Field Analyzer programs Central 30-2 and 10-2, and the GCCT using spectral domain optical coherence tomography. For the GCCT measurement, we selected 3 points each in the inner or outer sectors of the parafovea.
  
  
  RESULTS
  We observed a significant correlation between the macular GCCT of the inner or outer sector of the parafovea and in the change of the visual field in each hemifield defect or the apparently normal hemifield. The decrease of the GCCT corresponding to the apparently normal hemifield correlated with the progression of the severity of the glaucomatous defects, using the Anderson classification.
  
  
  CONCLUSIONS
  The macular GCCT is a sensitive marker of early glaucomatous change, allowing detection of structural changes associated with glaucoma even in the apparently normal hemifield.
authors.affiliation: *Department of Ophthalmology, Gifu University Graduate School of Medicine †Department of Ophthalmology, Gifu Municipal Hospital, Gifu, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Inuzuka
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Kawase
authors.forename: Hiroki
authors.initials: H
authors.lastname: Yamada
authors.forename: Shinya
authors.initials: S
authors.lastname: Oie
authors.forename: Satoko
authors.initials: S
authors.lastname: Kokuzawa
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis*; D006423:Hemianopsia / Q000175:diagnosis*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D012029:Refraction, Ocular / Q000502:physiology; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014065:Tonometry, Ocular; D014792:Visual Acuity / Q000502:physiology; D058609:Visual Field Tests; D014794:Visual Fields / Q000502:physiology