title: [Radiofrequency catheter ablation of the premature ventricular contractions originating from His bundle region].
abstract: OBJECTIVE
  To explore the electrocardiogram and 3-dimensional electroanatomic mapping features and radiofrequency catheter ablation efficacy of patients with premature ventricular contractions (PVCs ) originating from His bundle region.
  
  
  METHODS
  Between February 2009 and February 2011, 10 consecutive patients ( 4 male, aged from 19 to 59 years) who underwent ablation for frequent PVCs originating close to His bundle region in our department were included. Electroanatomic mapping of RVOT and ASC, ablation was performed with the 7F 4-mm-tip ablation catheter.
  
  
  RESULTS
  Among these 10 patients with PVCs originating from His bundle region, 6 originated from the RVOT, 1 from NCC and 3 from RCC. Eight patients showed LBBB morphology,1 patient with PVCs originated from RCC and 1 patient with PVCs originated from NCC showed RBBB morphology. At the successful ablation sites, local ventricular activation v wave was detected 22-52 (32.6 ± 10.2) ms earlier than the QRS wave in the surface electrocardiogram. The distance between target and His bundle was 5.0-8.4(7.0 ± 1.1)mm. Ablation was successful in all 10 patients without complications (PVCs < 500 beats/24 h post ablation).
  
  
  CONCLUSIONS
  PVCs originating near the His bundle have similar electrocardiographic and electrophysiological characteristics for PVSc originated from the RVOT or ASC. Because of the close anatomical relationship between RVOT and ASC, it is necessary to mapping both RVOT and ASC to accurately identify the site of PVCs origin and to guild successful ablation.
authors.affiliation: China Weifang Medical College, Beijing, China.
authors.forename: Yu-bin
authors.initials: YB
authors.lastname: Wang
authors.forename: Jian-min
authors.initials: JM
authors.lastname: Chu
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Shu-kai
authors.initials: SK
authors.lastname: Song
authors.forename: Xiao-yan
authors.initials: XY
authors.lastname: Liu
authors.forename: Qi
authors.initials: Q
authors.lastname: Guo
authors.forename: Jie-lin
authors.initials: JL
authors.lastname: Pu
authors.forename: Shu
authors.initials: S
authors.lastname: Zhang
mesh_terms: D000328:Adult; D002036:Bundle of His / Q000601:surgery*; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D018879:Ventricular Premature Complexes / Q000601:surgery*; D055815:Young Adult