title: I2/TBHP-catalyzed chemoselective amination of indoles.
abstract: A novel I2/TBHP-mediated direct oxidative diamination reaction of indoles with anilines was developed. The reaction proceeded smoothly under aqueous and open air reaction conditions. This protocol provides a practical synthetic method for the synthesis of Tryptanthrin and the construction of N-C3 linked pyrrolidinoindolines which is the core structure of Psychotrimine.
authors.affiliation: Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University , Suzhou 215123, China.
authors.forename: Zhong-Jian
authors.initials: ZJ
authors.lastname: Cai
authors.forename: Shun-Yi
authors.initials: SY
authors.lastname: Wang
authors.forename: Shun-Jun
authors.initials: SJ
authors.lastname: Ji
mesh_terms: D000586:Amination; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D018360:Crystallography, X-Ray; D007211:Indoles / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D020122:tert-Butylhydroperoxide / Q000737:chemistry*
chemical_list: D000588:Amines; D007211:Indoles; D020122:tert-Butylhydroperoxide; D007455:Iodine