title: Correlation of antibiotic prophylaxis and difficulty of extraction with postoperative inflammatory complications in the lower third molar surgery.
abstract: Our aim was to investigate the correlation among antibiotic prophylaxis, difficulty of extraction, and postoperative complications in the removal of lower 3rd molars. A total of 1222 such extractions in 890 patients between January 2010 and January 2012 were analysed retrospectively. The difficulty of extraction measured by Pederson's index, antibiotic prophylaxis with cefditoren, and postoperative complications were recorded. The difficulty of extraction was significantly associated with postoperative complications (p=0.03). There were no significant associations between antibiotic prophylaxis and postoperative complications in groups of equal difficulty ("easy" group (class I) p=1.00; "moderate" group (class II) p=1.00; and "difficult" group (class III) p=0.65). There was a small but insignificant increase in the number of dry sockets and infections in class III cases. In conclusion, this study provides further evidence that antibiotic prophylaxis for the prevention of postoperative inflammatory complications is unnecessary for extraction of 3rd molars.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Korea University Graduate School of Clinical Dentistry, Seoul, Republic of Korea. Electronic address: denti1@hanmail.net.
authors.forename: J Y
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Department of Oral and Maxillofacial Surgery, Korea University Graduate School of Clinical Dentistry, Seoul, Republic of Korea. Electronic address: progdo@hanmail.net.
authors.forename: H S
authors.initials: HS
authors.lastname: Do
authors.affiliation: Department of Oral and Maxillofacial Surgery, Korea University Graduate School of Clinical Dentistry, Seoul, Republic of Korea. Electronic address: surgidenta@hanmail.net.
authors.forename: J H
authors.initials: JH
authors.lastname: Lim
authors.affiliation: Department of Oral and Maxillofacial Surgery, Korea University Graduate School of Clinical Dentistry, Seoul, Republic of Korea. Electronic address: omfs1109@korea.ac.kr.
authors.forename: H S
authors.initials: HS
authors.lastname: Jang
authors.affiliation: Department of Oral and Maxillofacial Surgery, Korea University Graduate School of Clinical Dentistry, Seoul, Republic of Korea. Electronic address: jaesrim@korea.ac.kr.
authors.forename: J S
authors.initials: JS
authors.lastname: Rim
authors.affiliation: Department of Oral and Maxillofacial Surgery, Korea University Graduate School of Clinical Dentistry, Seoul, Republic of Korea. Electronic address: kwonjj@korea.ac.kr.
authors.forename: J J
authors.initials: JJ
authors.lastname: Kwon
authors.affiliation: Department of Oral and Maxillofacial Surgery, Korea University Graduate School of Clinical Dentistry, Seoul, Republic of Korea. Electronic address: ees225@hanmail.net.
authors.forename: E S
authors.initials: ES
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000766:Anesthesia, Dental / Q000379:methods; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis; D002511:Cephalosporins / Q000627:therapeutic use; D004368:Dry Socket / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery*; D008875:Middle Aged; D008964:Molar, Third / Q000601:surgery*; D009407:Nerve Block / Q000379:methods; D010027:Osteotomy / Q000379:methods; D010149:Postoperative Pain / Q000209:etiology; D011183:Postoperative Complications; D012189:Retrospective Studies; D013524:Surgical Flaps / Q000601:surgery; D013530:Surgical Wound Infection / Q000209:etiology; D014081:Tooth Extraction / Q000145:classification / Q000379:methods*; D014313:Trismus / Q000209:etiology; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; C073460:cefditoren
keywords: Antibiotic prophylaxis; Cefditoren; Difficulty of extraction; Mandibular third molar; Pederson's classification