title: A Bach2 link between pre-B cell receptor checkpoint and pre-B cell ALL.
abstract: Bach2 is a transcription factor required for affinity maturation of B cells. A recent study reveals, quite unexpectedly, that Bach2 also plays a key role in the pre-B cell receptor checkpoint and functions as a tumor suppressor in pre-B cell acute lymphocytic leukemia.
authors.affiliation: Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: hilda.ye@einstein.yu.edu.
authors.forename: B Hilda
authors.initials: BH
authors.lastname: Ye
authors.forename: Yun
authors.initials: Y
authors.lastname: Mai
mesh_terms: D000818:Animals; D050976:Basic-Leucine Zipper Transcription Factors / Q000378:metabolism*; D054420:Pre-B Cell Receptors / Q000378:metabolism*; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*
chemical_list: D050976:Basic-Leucine Zipper Transcription Factors; D054420:Pre-B Cell Receptors; D016159:Tumor Suppressor Protein p53