title: [Analysis on genotype distributions and epidemiological characteristics of Yersinia pestis plague foci in Gansu province].
abstract: OBJECTIVE
  To study the genotype distributions and epidemiological characteristics of Yersinia pestis in Gansu province.
  
  
  METHODS
  Primers were designed according to the confirmed 23 differential sections, to genotype the 202 Yersinia pestis DNA of Gansu province by PCR, and to analyze its distribution and epidemiological characteristics.
  
  
  RESULTS
  Yersinia pestis in Gansu province could be divided into eight genotypes: 1b, 5, 7, 8, 13, 26, new genotype 1 (GS1) and new genotype 2 (GS2). They were distributed in various regions. 1b, 8 and GS1 genotypes of Yersinia pestis had been identified since 1960s but the 7, 13 and 26 genotypes had not been isolated for more than 40 years while GS2 and 5 genotypes had been isolated since 1990s.
  
  
  CONCLUSIONS
  1b, 8 and GS1 genotypes of Yersinia pestis continued to be violently prevalent since 1960s but 7, 13 and 26 genotypes had not been isolated for more than 40 years while GS2 and 5 genotypes had started to be popular since 1990s.
authors.affiliation: Gansu Provincial Centre for Disease Control and Prevention, Lanzhou, China.
authors.forename: Xin-hua
authors.initials: XH
authors.lastname: Wang
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.forename: Li-min
authors.initials: LM
authors.lastname: Guo
authors.forename: Ke-jun
authors.initials: KJ
authors.lastname: Miao
authors.forename: Wen-ping
authors.initials: WP
authors.lastname: DA
authors.forename: Bin
authors.initials: B
authors.lastname: Wu
authors.forename: Da-qin
authors.initials: DQ
authors.lastname: Xu
authors.forename: Ya-jun
authors.initials: YJ
authors.lastname: Ge
authors.forename: Tao-xia
authors.initials: TX
authors.lastname: Mu
authors.forename: Guo-juan
authors.initials: GJ
authors.lastname: Chen
authors.forename: Xiao-yan
authors.initials: XY
authors.lastname: Zhou
authors.forename: Shi-ming
authors.initials: SM
authors.lastname: Wang
authors.forename: Peng-fei
authors.initials: PF
authors.lastname: Ge
authors.forename: Jin-xiao
authors.initials: JX
authors.lastname: Xi
mesh_terms: D000818:Animals; D002681:China / Q000453:epidemiology; D017931:DNA Primers; D014644:Genetic Variation; D016680:Genome, Bacterial; D005838:Genotype; D006801:Humans; D010930:Plague / Q000453:epidemiology* / Q000382:microbiology*; D015010:Yersinia pestis / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D017931:DNA Primers