title: Intrathyroidal parathyroid carcinoma mimicking a thyroid nodule in a MEN type 1 patient.
abstract: A 59-year-old woman with classic manifestations of hyperparathyroidism associated with multiple endocrine neoplasia type 1 presented with a right adrenal mass and two pituitary microadenomas on imaging studies. For evaluation of hypercalcemia, (99m) Tc-MIBI scintigraphy was done and showed focal uptake at the thyroid level of the right anterior neck. Subsequent neck sonography showed several thyroid nodules, but there was no parathyroid tumor. Percutaneous fine-needle aspiration of the dominant thyroid nodule indicated a follicular nodule. After surgery, final histopathology revealed intrathyroidal parathyroid carcinoma. This case illustrates the difficulty in diagnosing parathyroid carcinoma via fine-needle aspiration.
authors.affiliation: Department of Radiology, Graduate College of Medicine, Kyung Hee University, #26 Kyunghee-daero, Dongdaemun-gu, Seoul, 130-702, Korea.
authors.forename: Kyung Mi
authors.initials: KM
authors.lastname: Lee
authors.forename: Eui Jong
authors.initials: EJ
authors.lastname: Kim
authors.forename: Woo Suk
authors.initials: WS
authors.lastname: Choi
authors.forename: Won Seo
authors.initials: WS
authors.lastname: Park
authors.forename: Sung Won
authors.initials: SW
authors.lastname: Kim
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D018761:Multiple Endocrine Neoplasia Type 1 / Q000150:complications*; D010280:Parathyroid Glands / Q000000981:diagnostic imaging* / Q000601:surgery; D010282:Parathyroid Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging* / Q000601:surgery; D013964:Thyroid Neoplasms / Q000175:diagnosis; D016606:Thyroid Nodule / Q000175:diagnosis; D014463:Ultrasonography
keywords: multiple endocrine neoplasia type 1; parathyroid, carcinoma, ectopic location; ultrasonography