title: Clear cell carcinoma of female urethral diverticulum--a case report.
abstract: Primary malignancies of female urethral diverticulum are rare. A well-documented female patient with primary clear cell carcinoma of the urethral diverticulum is presented here. A 65-year-old woman presented with frequency and voiding difficulty for 2 months. Physical examination showed a 4-cm mass protruding from anterior vaginal wall. Intravenous urography, magnetic resonance imaging, and cystoscopy showed a polypoid mass in urethral diverticulum. She then underwent anterior exenteration with ileal conduit diversion and urethrectomy. Pathology confirmed the diagnosis of clear cell adenocarcinoma with bladder neck invasion. She had no disease recurrence at 2-year follow-up. Careful clinical examination and image studies are helpful in making the preoperative diagnosis for the rare disease. Early radical surgery can achieve better survival.
authors.affiliation: Department of Urology, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Wen-Ching
authors.initials: WC
authors.lastname: Weng
authors.forename: Chung-Chieh
authors.initials: CC
authors.lastname: Wang
authors.forename: Chen-Hsun
authors.initials: CH
authors.lastname: Ho
authors.forename: Hong-Chiang
authors.initials: HC
authors.lastname: Chang
authors.forename: Shyh-Chyan
authors.initials: SC
authors.lastname: Chen
authors.forename: Hong-Jeng
authors.initials: HJ
authors.lastname: Yu
authors.forename: Kuo-How
authors.initials: KH
authors.lastname: Huang
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D000368:Aged; D004240:Diverticulum / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D014522:Urethral Diseases / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D014523:Urethral Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*
keywords: clear cell carcinoma; urethral diverticulum