title: Idiopathic urolithiasis in Tunisian children: a report of 134 cases.
abstract: We evaluated the metabolic and the nutritional aspects of 134 urolithiasis children in order to outline the characteristics of idiopathic urolithiasis in children. This prospective study group of 134 children (56 females, 78 males) with renal calculi was evaluated. The age range of the patients was six months to 16 years. A dietary survey was performed on every child. All patients were investigated with respect to stone localization and serum and urine risk factors. Statistical analysis of data was carried out using software SPSS 11.0 for Windows. Hypercalciuria was the most common risk factor detected in this group (28.3%). A decrease of water intake was noted in all age groups, especially in the rural area (549.6 mL/day vs. 1150.6 mL/day), and there was an increase in animal protein intake in 17 cases (mean: 1.9 g/kg). In addition, increased intake of starchy foods and food with high oxalate content (sorgum) were detected in the ten to 16 years age group (51%) of our study. Calcium oxalate monohydrate represents the principal component of idiopathic stone (58.2%), which is more frequent in children (68%) than in infants (51.7%) (P <0.02). The major etiology of idiopathic urolithiasis highlights the influence of dietary habit in stone formers in our country. The increased occurrence of calcium oxalate stones in school age children confirms the change in the etiology of urolithiasis according to age.
authors.affiliation: Department of Biochemistry and Toxicology, Unité de Nutrition et Métaux Lourds, Monastir, Tunisia. akram_alaya@yahoo.co.uk
authors.forename: A
authors.initials: A
authors.lastname: Alaya
authors.forename: R
authors.initials: R
authors.lastname: Sakly
authors.forename: A
authors.initials: A
authors.lastname: Nouri
authors.forename: M F
authors.initials: MF
authors.lastname: Najjar
authors.forename: M
authors.initials: M
authors.lastname: Belgith
authors.forename: R
authors.initials: R
authors.lastname: Jouini
mesh_terms: D000293:Adolescent; D002129:Calcium Oxalate / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D004032:Diet; D004034:Diet Surveys; D004044:Dietary Proteins; D005260:Female; D006801:Humans; D053565:Hypercalciuria / Q000453:epidemiology; D007223:Infant; D007669:Kidney Calculi / Q000737:chemistry / Q000453:epidemiology*; D008297:Male; D011446:Prospective Studies; D014416:Tunisia
chemical_list: D004044:Dietary Proteins; D002129:Calcium Oxalate