title: 6-(4-Meth-oxy-phen-yl)-6a-nitro-6,6a,6b,7,8,9,10,12a-octa-hydro-spiro-[chromeno[3,4-a]indolizine-12,3'-indolin]-2'-one.
abstract: In the title compound, C29H27N3O5, the hydropyran ring adopts an envelope conformation with the methine C atom bearing the para-meth-oxy-benzene ring as the flap. The central pyrrolidine ring has a twist conformation on the N-C bond involving the spiro C atom. The piperidine ring adopts a chair conformation. An intra-molecular C-H⋯O contact closes an S(7) ring. In the crystal, inversion dimers linked by C-H⋯O inter-actions generate R 2 (2)(18) loops and N-H⋯O hydrogen bonds connect the dimers into [100] chains.
authors.affiliation: Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India.
authors.forename: Seenivasan Karthiga
authors.initials: SK
authors.lastname: Devi
authors.forename: Thothadri
authors.initials: T
authors.lastname: Srinivasan
authors.forename: Jonnalagadda Naga Siva
authors.initials: JN
authors.lastname: Rao
authors.forename: Raghavachary
authors.initials: R
authors.lastname: Raghunathan
authors.forename: Devadasan
authors.initials: D
authors.lastname: Velmurugan
references.citation: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references.pmid: 18156677
references.citation: Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55
references.pmid: 19171970
references.citation: Acta Crystallogr Sect E Struct Rep Online. 2013 May 31;69(Pt 6):o993
references.pmid: 23795144