title: Mortality among Japanese with a history of Kawasaki disease: results at the end of 2009.
abstract: BACKGROUND
  The long-term outcomes of Kawasaki disease (KD) are unknown.
  
  
  METHODS
  Fifty-two collaborating hospitals collected data on all patients who had received a new definite diagnosis of KD between July 1982 and December 1992. Patients were followed until December 31, 2009 or death. Standardized mortality ratios (SMRs) were calculated based on Japanese vital statistics data.
  
  
  RESULTS
  Of the 6576 patients enrolled, 46 (35 males and 11 females) died (SMR: 1.00; 95% CI: 0.73-1.34). Among persons without cardiac sequelae, SMRs were not high after the acute phase of KD (SMR: 0.65; 95% CI: 0.41-0.96). Among persons with cardiac sequelae, 13 males and 1 female died during the observation period (SMR: 1.86; 95% CI: 1.02-3.13).
  
  
  CONCLUSIONS
  In this cohort, the mortality rate among Japanese with cardiac sequelae due to KD was significantly higher than that of the general population. In contrast, the rates for males and females without sequelae were not elevated.
authors.affiliation: Department of Public Health, Jichi Medical University.
authors.forename: Yosikazu
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Eiko
authors.initials: E
authors.lastname: Aso
authors.forename: Mayumi
authors.initials: M
authors.lastname: Yashiro
authors.forename: Satoshi
authors.initials: S
authors.lastname: Tsuboi
authors.forename: Takao
authors.initials: T
authors.lastname: Kojo
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Aoyama
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Kotani
authors.forename: Ritei
authors.initials: R
authors.lastname: Uehara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yanagawa
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006331:Heart Diseases / Q000209:etiology; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications / Q000401:mortality*; D015996:Survival Rate; D055815:Young Adult
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