title: An in vitro evaluation of the biological effects of carbon nanotube-coated dental zirconia.
abstract: THE PURPOSE OF THIS STUDY IS TO EVALUATE FUNCTIONALIZED MULTIWALLED CARBON NANOTUBES (FMWCNTS) AS A POTENTIAL COATING MATERIAL FOR DENTAL ZIRCONIA FROM A BIOLOGICAL PERSPECTIVE: its effect on cell proliferation, viability, morphology, and the attachment of an osteoblast-like cell. Osteoblast-like (Saos-2) cells were seeded on uncoated and fMWCNT-coated zirconia discs and in culture dishes that served as controls. The seeding density was 10(4) cells/cm(2), and the cells were cultured for 6 days. Cell viability, proliferation and attachment of the Saos-2 cells were studied. The results showed that Saos-2 cells were well attached to both the uncoated and the fMWCNT-coated zirconia discs. Cell viability and proliferation on the fMWCNT-coated zirconia discs were almost the same as for the control discs. Better cell attachment was seen on the fMWCNT-coated than on the uncoated zirconia discs. In conclusion, fMWCNTs seem to be a promising coating material for zirconia-based ceramic surfaces to increase the roughness and thereby enhance the osseointegration of zirconia implants.
authors.affiliation: Dental Materials Science, Department of Odontology, Faculty of Medicine, Umeå University, 90781 Umeå, Sweden.
authors.forename: Wen
authors.initials: W
authors.lastname: Kou
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Akasaka
authors.forename: Fumio
authors.initials: F
authors.lastname: Watari
authors.forename: Göran
authors.initials: G
authors.lastname: Sjögren
references.citation: Biomed Mater. 2010 Apr;5(2):22001
references.pmid: 20339169
references.citation: J Biomed Mater Res. 2001 Jan;54(1):139-48
references.pmid: 11077413
references.citation: Biomed Mater Eng. 2012;22(6):383-98
references.pmid: 23114467
references.citation: J Am Chem Soc. 2003 Dec 10;125(49):15174-82
references.pmid: 14653752
references.citation: Chem Soc Rev. 2012 Mar 21;41(6):2323-43
references.pmid: 22170510
references.citation: Biomed Mater Eng. 2009;19(2-3):147-53
references.pmid: 19581708
references.citation: J Biomed Mater Res B Appl Biomater. 2009 Aug;90(2):629-34
references.pmid: 19213050
references.citation: J Oral Rehabil. 2011 Apr;38(4):286-94
references.pmid: 20969613
references.citation: Biomed Mater Eng. 2009;19(1):45-52
references.pmid: 19458445
references.citation: Chem Rev. 1999 Jul 14;99(7):1787-1800
references.pmid: 11849010
references.citation: Acc Chem Res. 2013 Mar 19;46(3):702-13
references.pmid: 22999420
references.citation: Clin Oral Implants Res. 2012 Mar;23(3):287-93
references.pmid: 21545535
references.citation: Clin Oral Implants Res. 2009 Sep;20 Suppl 4:32-47
references.pmid: 19663947
references.citation: Nanomedicine. 2010 Apr;6(2):245-56
references.pmid: 19699321
references.citation: Mol Biosyst. 2005 Jul;1(2):176-82
references.pmid: 16880981
references.citation: Int J Nanomedicine. 2012;7:5361-74
references.pmid: 23091380