title: Chikungunya fever outbreak, Bhutan, 2012.
abstract: In 2012, chikungunya virus (CHIKV) was reported for the first time in Bhutan. IgM ELISA results were positive for 36/210 patient samples; PCR was positive for 32/81. Phylogenetic analyses confirmed that Bhutan CHIKV belongs to the East/Central/South African genotype. Appropriate responses to future outbreaks require a system of surveillance and improved laboratory capacity.
authors.forename: Sonam
authors.initials: S
authors.lastname: Wangchuk
authors.forename: Piyawan
authors.initials: P
authors.lastname: Chinnawirotpisan
authors.forename: Tshering
authors.initials: T
authors.lastname: Dorji
authors.forename: Tashi
authors.initials: T
authors.lastname: Tobgay
authors.forename: Tandin
authors.initials: T
authors.lastname: Dorji
authors.forename: In-Kyu
authors.initials: IK
authors.lastname: Yoon
authors.forename: Stefan
authors.initials: S
authors.lastname: Fernandez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018354:Alphavirus Infections / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D000595:Amino Acid Sequence; D000914:Antibodies, Viral / Q000097:blood; D001631:Bhutan / Q000453:epidemiology; D065632:Chikungunya Fever; D002646:Chikungunya virus / Q000235:genetics / Q000276:immunology* / Q000302:isolation & purification; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D007223:Infant; D008297:Male; D008875:Middle Aged; D025202:Molecular Diagnostic Techniques; D008969:Molecular Sequence Data; D010802:Phylogeny; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014759:Viral Envelope Proteins / Q000235:genetics; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M; D014759:Viral Envelope Proteins
keywords: Aedes aegypti; Aedes albopictus; Alphavirus; Bhutan; Chikungunya fever; Chikungunya virus; Togaviridae; outbreak; re-emerging disease; viruses
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