title: Imidazoles as promising scaffolds for antibacterial activity: a review.
abstract: In the last few decades, a lot of work has been done on heterocycles, especially the imidazole ring, to obtain a scaffold with potential pharmacological properties such as antibacterial, antifungal, anticancer, antiviral, antidiabetic and others, with lesser side effects. The search for new biologically active imidazoles continues to be an interesting area of investigation in medicinal chemistry. The present paper aims to bring together and discuss the wealth of information on antibacterial profile of imidazoles. So it can be employed for future development to obtain new potent drug molecules.
authors.affiliation: Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India. nidhiprajapati8@gmail.com.
authors.forename: Nidhi
authors.initials: N
authors.lastname: Rani
authors.forename: Ajay
authors.initials: A
authors.lastname: Sharma
authors.forename: Randhir
authors.initials: R
authors.lastname: Singh
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D010330:Patents as Topic; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D056831:Coordination Complexes; D007093:Imidazoles; C029899:imidazole