title: Bilateral sudden hearing loss following habitual abortion: a case report and review of literature.
abstract: Sudden sensorineural hearing loss (SSNHL) is usually unilateral and can be associated with tinnitus and vertigo. The most common causes of this disease are known to be the vascular and viral agents, but immune disorders are involved in the development of sudden deafness. The antiphospholipid syndrome (APS) is an acquired autoimmune system disorder, which is defined as the presence of antiphospholipid antibodies (APA) in the patient's blood, then cause venous and/or arterial thrombosis in various organs of the body, for example, thrombosis can occur in the placenta and/or the inner ear. As a result, it can cause abortion and/or sudden deafness. Bilateral SSNHL following habitual abortion is a rare clinical event. Here, we report a case of 32-year-old woman who presented with bilateral sudden hearing loss following recurrent pregnancy loss (RPL) as the first manifestation of primary antiphospholipid syndrome. Combine the literature, the diagnosis, clinical implication and treatment are discussed.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, The Second Xiangya Hospital, Central South University Changsha, Hunan, China, 410011.
authors.forename: Tuanfang
authors.initials: T
authors.lastname: Yin
authors.forename: Fengying
authors.initials: F
authors.lastname: Huang
authors.forename: Jihao
authors.initials: J
authors.lastname: Ren
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Xing
authors.initials: X
authors.lastname: Chen
authors.forename: Lihua
authors.initials: L
authors.lastname: Li
authors.forename: Dinghua
authors.initials: D
authors.lastname: Xie
authors.forename: Yongde
authors.initials: Y
authors.lastname: Lu
keywords: Sudden sensorineural hearing loss (SSNHL); anticardiolipin antibody (ACA); antiphospholipid antibody (APA); antiphospholipid syndrome (APS); autoimmune disease; habitual abortion; recurrent pregnancy loss (RPL); thrombosis
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