title: Successful treatment of extensive cerebral venous sinus thrombosis using a combined approach with Penumbra aspiration system and Solitaire FR retrieval device.
abstract: We present a young woman with rapidly progressive neurologic decline in the setting of malignant cerebral edema due to extensive superior sagittal sinus thrombosis and cortical venous thrombosis despite intravenous heparin administration. Complete revascularization of the occluded sinus was achieved using suction thrombectomy with the 5 max Penumbra catheter in combination with the Solitaire FR clot retrieval device. The successful endovascular treatment halted the progression of her cerebral edema, and the patient eventually had an excellent recovery after prolonged intensive medical therapy. To our knowledge, this is the first reported case describing such a combined mechanical approach for cerebral venous sinus thrombosis. The clot retrieval properties of the Solitaire device combined with direct aspiration via the newest generation Penumbra catheters may allow more rapid, safe and efficient revascularization than all previously reported endovascular treatments for this potentially devastating condition.
authors.affiliation: Division of Interventional Neuroradiology, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
authors.forename: Radoslav
authors.initials: R
authors.lastname: Raychev
authors.forename: Satoshi
authors.initials: S
authors.lastname: Tateshima
authors.forename: Sachin
authors.initials: S
authors.lastname: Rastogi
authors.forename: Amit
authors.initials: A
authors.lastname: Balgude
authors.forename: Banafsheh
authors.initials: B
authors.lastname: Yafeh
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Saver
authors.forename: Paul M
authors.initials: PM
authors.lastname: Vespa
authors.forename: Manuel
authors.initials: M
authors.lastname: Buitrago
authors.forename: Gary
authors.initials: G
authors.lastname: Duckwiler
mesh_terms: D000328:Adult; D001929:Brain Edema / Q000150:complications; D005260:Female; D006801:Humans; D020767:Intracranial Thrombosis / Q000150:complications; D020225:Sagittal Sinus Thrombosis / Q000601:surgery*; D013396:Suction / Q000379:methods; D017131:Thrombectomy / Q000379:methods*; D016896:Treatment Outcome
keywords: Hemorrhage; Intracranial Pressure; Stroke; Thrombectomy; Vein
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