title: Response to Comment on "Influence of HLA-C expression level on HIV control".
abstract: Lo Monaco et al. propose that human leukocyte antigen E (HLA-E) and HLA-C expression levels both contribute to HIV control. The minimal, flat level of cell surface HLA-E detectable by staining with available HLA-E-specific antibodies questions a role for differential HLA-E expression in determining HIV control. Evidence remains far stronger that HLA-C expression levels as detected by the DT9 antibody specifically affect HIV control.
authors.affiliation: Cancer and Inflammation Program, Laboratory of Experimental Immunology, Science Applications International Corporation Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Apps
authors.forename: Mary
authors.initials: M
authors.lastname: Carrington
mesh_terms: D005786:Gene Expression Regulation; D006678:HIV / Q000276:immunology*; D015658:HIV Infections / Q000235:genetics* / Q000276:immunology*; D015236:HLA-C Antigens / Q000235:genetics*; D006801:Humans; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*
chemical_list: D015236:HLA-C Antigens
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