title: A case report of AA amyloidosis associated with familial periodic fever syndrome diagnosed after kidney transplantation: never say never.
abstract: Recurrent or "de novo" AA amyloidosis in the renal allograft is rarely described. We describe a case of severe nephrotic syndrome in a recipient of a kidney graft with a previous diagnosis of polycystic nephropathy caused by AA amyloidosis diagnosed only after the renal transplantation. The disease was possibly a tumor necrosis factor receptor-associated periodic syndrome (TRAPS). TRAPS is a rare hereditary inflammatory disease never reported to the best of our knowledge, as a de novo diagnosis in the transplantation setting. Biopsy of the renal graft, indicated for the onset of heavy proteinuria, and genetic investigation provided the clues for diagnosis.
authors.affiliation: Division of Nephrology, Dialysis, and Transplantation, Department of Medical Science, San Giovanni Battista Hospital and University of Turin, Turin, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Messina
authors.forename: G
authors.initials: G
authors.lastname: Daidola
authors.forename: G
authors.initials: G
authors.lastname: Restagno
authors.forename: A
authors.initials: A
authors.lastname: Lavacca
authors.forename: A
authors.initials: A
authors.lastname: Ranghino
authors.forename: L
authors.initials: L
authors.lastname: Biancone
authors.forename: G P
authors.initials: GP
authors.lastname: Segoloni
mesh_terms: D000686:Amyloidosis / Q000150:complications*; D005334:Fever / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D016030:Kidney Transplantation; D007690:Polycystic Kidney Diseases / Q000601:surgery