title: Electrophile induced branching cascade: a powerful approach to access various molecular scaffolds and their exploration as novel anti-mycobacterial agents.
abstract: Herein we report on the Electrophile Induced Branching Cascade (EIBC), a new technique to produce a variety of biologically important molecular scaffolds. Some compounds exhibit excellent activities against Mycobacterium smegmatis.
authors.affiliation: CSIR - Indian Institute of Chemical Technology, Hyderabad - 500 007, India.
authors.forename: Nitin T
authors.initials: NT
authors.lastname: Patil
authors.forename: Ashok
authors.initials: A
authors.lastname: Konala
authors.forename: Sudha
authors.initials: S
authors.lastname: Sravanti
authors.forename: Ashita
authors.initials: A
authors.lastname: Singh
authors.forename: Ramesh
authors.initials: R
authors.lastname: Ummanni
authors.forename: Balasubramanian
authors.initials: B
authors.lastname: Sridhar
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D004353:Drug Evaluation, Preclinical; D015394:Molecular Structure; D020102:Mycobacterium smegmatis / Q000187:drug effects*; D054852:Small Molecule Libraries / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D013237:Stereoisomerism
chemical_list: D000900:Anti-Bacterial Agents; D054852:Small Molecule Libraries