title: Titanium hypersensitivity. A hidden threat for dental implant patients?
abstract: Titanium and its alloys have been widely used for dental prosthetic devices because of their superior mechanical properties and biocompatibility. However, the incidence of titanium hypersensitivity or allergy is still unknown and the discussion about its existence is ongoing. Unexplained implant failures have also forced dental clinicians to investigate the possibility of titanium hypersensitivity or allergy. This review focuses on the potential of dental implant-related titanium hypersensitivity or allergic reactions. It includes an examination of the existing scientific literature and current knowledge. Evidence-based data and studies related to titanium hypersensitivity in dental implant patients are also discussed.
authors.affiliation: Department of Prosthodontics, Istanbul University, Faculty of Dentistry, Istanbul, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Bilhan
authors.forename: Canan
authors.initials: C
authors.lastname: Bural
authors.forename: Onur
authors.initials: O
authors.lastname: Geckili
mesh_terms: D001672:Biocompatible Materials / Q000009:adverse effects; D003722:Dental Alloys / Q000009:adverse effects; D015921:Dental Implants / Q000009:adverse effects*; D003764:Dental Materials / Q000009:adverse effects*; D019232:Dental Restoration Failure; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology* / Q000276:immunology; D014025:Titanium / Q000009:adverse effects* / Q000276:immunology
chemical_list: D001672:Biocompatible Materials; D003722:Dental Alloys; D015921:Dental Implants; D003764:Dental Materials; D014025:Titanium