title: Surface rendering of external genitalia of a fetus at the 32nd week of gestation affected by partial androgen insensitivity syndrome.
abstract: Objectives. To demonstrate the feasibility of the prenatal diagnosis of partial androgen insensitivity syndrome by 3D-4D ultrasound. Methods. To report prenatal diagnosis of partial androgen insensitivity syndrome at 32nd week of gestation by 3D-4D ultrasound in a fetus with a 46XY karyotype, testing negative to the mutation analysis of SRY gene and the 5 α -reductase 2 gene (SRD5A2). Results. 3D-4D surface rendering allows the detection of external and internal genital malformations and can address the prenatal diagnosis of PAIS and can exclude associated complications. Conclusions. Prenatal diagnosis of PAIS allows an adequate parental counseling and an early optimal management of the condition, not only for the psychological and social reflections but also for the avoidance of complications and postnatal morbidity due to misdiagnosis or delays in the treatment of the genital ambiguity.
authors.affiliation: Prenatal Medicine Unit, Policlinico Modena, Via Largo Del Pozzo 71, 41124 Modena, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Mazza
authors.forename: Emma
authors.initials: E
authors.lastname: Bertucci
authors.forename: Silvia
authors.initials: S
authors.lastname: Latella
authors.forename: Carlotta
authors.initials: C
authors.lastname: Cani
authors.forename: Pierluca
authors.initials: P
authors.lastname: Ceccarelli
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Iughetti
authors.forename: Fulvia
authors.initials: F
authors.lastname: Baldinotti
authors.forename: Antonio
authors.initials: A
authors.lastname: Percesepe
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