title: Murine models of human wound healing.
abstract: In vivo wound healing experiments remain the most predictive models for studying human wound healing, allowing an accurate representation of the complete wound healing environment including various cell types, environmental cues, and paracrine interactions. Small animals are economical, easy to maintain, and allow researchers to take advantage of the numerous transgenic strains that have been developed to investigate the specific mechanisms involved in wound healing and regeneration. Here we describe three reproducible murine wound healing models that recapitulate the human wound healing process.
authors.affiliation: Department of Surgery, Stanford University, Stanford, CA, USA.
authors.forename: Jerry S
authors.initials: JS
authors.lastname: Chen
authors.forename: Michael T
authors.initials: MT
authors.lastname: Longaker
authors.forename: Geoffrey C
authors.initials: GC
authors.lastname: Gurtner
mesh_terms: D000818:Animals; D001706:Biopsy; D004195:Disease Models, Animal; D006801:Humans; D051379:Mice; D014945:Wound Healing; D014947:Wounds and Injuries / Q000209:etiology* / Q000473:pathology
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