title: Implant stability change and osseointegration speed of immediately loaded photofunctionalized implants.
abstract: OBJECTIVE
  This study evaluated the degree and rate of implant stability development for photofunctionalized dental implants in humans.
  
  
  METHODS
  Thirty-three implants (7 patients) placed in the maxilla and immediate loaded were evaluated. Photofunctionalization was performed by treating implants with ultraviolet for 15 minutes immediately before placement. Implant stability was assessed by measuring the implant stability quotient (ISQ) weekly starting from implant placement up to 3 months. Osseointegration speed index (OSI), defined as ISQ increase per month, was also evaluated.
  
  
  RESULTS
  The average ISQ for photofunctionalized implants at week 6 was 78.0, which was considerably higher than the average ISQ of 66.1, reported in literature for various as-received implants after a longer healing time of 2 to 6 months. No stability dip was observed for photofunctionalized implants regardless of the initial ISQ values. The OSI for photofunctionalized implants was 6.3 and 3.1 when their initial ISQ was 65 to 70 and 71 to 75, respectively, whereas the OSI values for as-received implants calculated from literature ranged from -3.0 to 1.17 with an average of -0.10.
  
  
  CONCLUSIONS
  Photofunctionalization accelerated and enhanced osseointegration of dental implants, providing novel and practical avenues for further advancement in implant therapy.
authors.affiliation: *Director, Lion Implant Center, Kanagawa, Japan. †Professor, Department of Hospital Administration, Juntendo University School of Medicine, Tokyo, Japan. ‡Professor, The Weintraub Center for Reconstructive Biotechnology, Division of Advanced Prosthodontics, University of California, Los Angeles, School of Dentistry, Los Angeles, CA.
authors.forename: Senichi
authors.initials: S
authors.lastname: Suzuki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Takahiro
authors.initials: T
authors.lastname: Ogawa
mesh_terms: D000368:Aged; D003758:Dental Implantation, Endosseous / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016348:Osseointegration; D013997:Time Factors; D014025:Titanium; D016896:Treatment Outcome; D014467:Ultraviolet Therapy / Q000379:methods*; D014945:Wound Healing
chemical_list: D014025:Titanium