title: Towards a more open debate about values in decision-making on agricultural biotechnology.
abstract: Regulatory decision-making over the use of products of new technology aims to be based on science-based risk assessment. In some jurisdictions, decision-making about the cultivation of genetically modified (GM) plants is blocked supposedly because of scientific uncertainty about risks to the environment. However, disagreement about the acceptability of risks is primarily a dispute over normative values, which is not resolvable through natural sciences. Natural sciences may improve the quality and relevance of the scientific information used to support environmental risk assessments and make scientific uncertainties explicit, but offer little to resolve differences about values. Decisions about cultivating GM plants will thus not necessarily be eased by performing more research to reduce scientific uncertainty in environmental risk assessments, but by clarifying the debate over values. We suggest several approaches to reveal values in decision-making: (1) clarifying policy objectives; (2) determining what constitutes environmental harm; (3) making explicit the factual and normative premises on which risk assessments are based; (4) better demarcating environmental risk assessment studies from ecological research; (5) weighing the potential for environmental benefits (i.e., opportunities) as well as the potential for environmental harms (i.e., risks); and (6) expanding participation in the risk governance of GM plants. Recognising and openly debating differences about values will not remove controversy about the cultivation of GM plants. However, by revealing what is truly in dispute, debates about values will clarify decision-making criteria.
authors.affiliation: GMO Unit, European Food Safety Authority (EFSA), Via Carlo Magno 1, 43126, Parma, Italy, Yann.Devos@efsa.europa.eu.
authors.forename: Yann
authors.initials: Y
authors.lastname: Devos
authors.forename: Olivier
authors.initials: O
authors.lastname: Sanvido
authors.forename: Joyce
authors.initials: J
authors.lastname: Tait
authors.forename: Alan
authors.initials: A
authors.lastname: Raybould
mesh_terms: D001709:Biotechnology / Q000331:legislation & jurisprudence*; D018556:Crops, Agricultural; D003657:Decision Making; D004784:Environmental Monitoring / Q000331:legislation & jurisprudence*; D006801:Humans; D030821:Plants, Genetically Modified; D011050:Policy Making; D018570:Risk Assessment
references.citation: GM Crops. 2010 Jan-Feb;1(1):25-31
references.pmid: 21912209
references.citation: Trends Biotechnol. 2013 Sep;31(9):493-6
references.pmid: 23973171
references.citation: EMBO Rep. 2012 Feb 01;13(2):100-5
references.pmid: 22240974
references.citation: Environ Biosafety Res. 2003 Apr-Jun;2(2):81-8
references.pmid: 15612274
references.citation: Nature. 2013 May 2;497(7447):22-3
references.pmid: 23636377
references.citation: Environ Biosafety Res. 2006 Jul-Sep;5(3):119-25
references.pmid: 17445509
references.citation: EMBO Rep. 2011 Jul 15;12(8):763-8
references.pmid: 21760612
references.citation: Science. 2005 Feb 11;307(5711):815
references.pmid: 15705810
references.citation: Nat Biotechnol. 2013 Jun;31(6):498-500
references.pmid: 23752432
references.citation: Science. 2005 Dec 23;310(5756):1908-9
references.pmid: 16373561
references.citation: EMBO Rep. 2004 Nov;5(11):1021-4
references.pmid: 15520800
references.citation: Ecol Evol. 2013 Aug;3(8):2739-50
references.pmid: 24567836
references.citation: Transgenic Res. 2010 Jun;19(3):425-36
references.pmid: 19757133
references.citation: GM Crops. 2011 Jan-Mar;2(1):7-23
references.pmid: 21844695
references.citation: Transgenic Res. 2012 Feb;21(1):1-21
references.pmid: 21526422
references.citation: Transgenic Res. 2010 Feb;19(1):1-12
references.pmid: 19548100
references.citation: Transgenic Res. 2012 Aug;21(4):691-8
references.pmid: 22476694
references.citation: Trends Plant Sci. 2003 May;8(5):208-12
references.pmid: 12758037
references.citation: Sci Total Environ. 2012 Jan 15;415:31-8
references.pmid: 21733564
references.citation: Nat Biotechnol. 2011 Apr;29(4):315-7
references.pmid: 21478843
references.citation: Nature. 2007 Dec 13;450(7172):921
references.pmid: 18075528
references.citation: EMBO Rep. 2009 Aug;10 Suppl 1:S18-22
references.pmid: 19636298
references.citation: Trends Biotechnol. 2008 Mar;26(3):122-5
references.pmid: 18243381
references.citation: GM Crops Food. 2012 Jan-Mar;3(1):9-20
references.pmid: 22430852
references.citation: EMBO Rep. 2012 Oct;13(10):885-9
references.pmid: 22986553
references.citation: Nat Biotechnol. 2013 May;31(5):386-7
references.pmid: 23657387
references.citation: Nature. 2009 Sep 3;461(7260):27-32
references.pmid: 19727179
references.citation: Environ Biosafety Res. 2009 Apr-Jun;8(2):65-78
references.pmid: 19833074
references.citation: Transgenic Res. 2011 Feb;20(1):1-22
references.pmid: 20938806
references.citation: Conserv Biol. 2007 Feb;21(1):12-7
references.pmid: 17298504
references.citation: Transgenic Res. 2013 Apr;22(2):255-67
references.pmid: 23430588
references.citation: Transgenic Res. 2014 Feb;23(1):1-25
references.pmid: 23963741
references.citation: Environ Biosafety Res. 2003 Jul-Sep;2(3):161-71
references.pmid: 15612414
references.citation: EMBO Rep. 2007 Apr;8(4):309-15
references.pmid: 17401403
references.citation: Nat Biotechnol. 2006 Jul;24(7):748-9
references.pmid: 16841049
references.citation: Nat Biotechnol. 2009 Jul;27(7):592-4
references.pmid: 19587656
references.citation: Trends Plant Sci. 2007 Jan;12(1):1-5
references.pmid: 17161972
references.citation: Environ Int. 2006 Dec;32(8):1066-71
references.pmid: 16899295
references.citation: Pest Manag Sci. 2005 Mar;61(3):318-25
references.pmid: 15627240
references.citation: Adv Biochem Eng Biotechnol. 2007;107:235-78
references.pmid: 17522828
references.citation: Transgenic Res. 2010 Feb;19(1):13-6
references.pmid: 19565349
references.citation: Environ Biosafety Res. 2010 Jul-Sep;9(3):123-33
references.pmid: 21975253
references.citation: Trends Plant Sci. 2013 Jun;18(6):312-24
references.pmid: 23623240
references.citation: Annu Rev Plant Biol. 2009;60:511-59
references.pmid: 19400729