title: Migraine Mistakes: Error Awareness.
abstract: Error awareness or detection is the conscious and subconscious processing to evaluate physiological signals that are different from a baseline or homeostatic level. Migraine is a unique neurological disorder in which there are repeated attacks interspersed by attack-free periods. These attacks are dynamic and multidimensional in the sense that sensory, affective, autonomic, and cognitive functions are altered and these changes evolve differently before (pre-ictal), during (ictal), and immediately after (post-ictal) an attack. Thus migraine serves as a model disease to understand how the brain monitors and react to the presence of errors.
authors.affiliation: Center for Pain and the Brain and PAIN Group (Boston Children's Hospital, Massachusetts General Hospital, and McLean Hospital), Harvard Medical School, Boston, MA, USA dborsook@partners.org.
authors.forename: David
authors.initials: D
authors.lastname: Borsook
authors.affiliation: Center for Pain and the Brain and PAIN Group (Boston Children's Hospital, Massachusetts General Hospital, and McLean Hospital), Harvard Medical School, Boston, MA, USA.
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Aasted
authors.affiliation: Beth Israel Deaconess Hospital, Harvard Medical School, Boston, MA, USA.
authors.forename: Rami
authors.initials: R
authors.lastname: Burstein
authors.affiliation: Center for Pain and the Brain and PAIN Group (Boston Children's Hospital, Massachusetts General Hospital, and McLean Hospital), Harvard Medical School, Boston, MA, USA.
authors.forename: Lino
authors.initials: L
authors.lastname: Becerra
mesh_terms: D001364:Awareness / Q000502:physiology*; D001921:Brain / Q000503:physiopathology*; D006801:Humans; D008881:Migraine Disorders / Q000503:physiopathology*
keywords: basal ganglia; headache; insula; neural networks; pain