title: Variant human T-cell lymphotropic virus type 1c and adult T-cell leukemia, Australia.
abstract: Human T-cell lymphotropic virus type 1 is endemic to central Australia among Indigenous Australians. However, virologic and clinical aspects of infection remain poorly understood. No attempt has been made to control transmission to indigenous children. We report 3 fatal cases of adult T-cell leukemia/lymphoma caused by human T-cell lymphotropic virus type 1 Australo-Melanesian subtype c.
authors.forename: Lloyd
authors.initials: L
authors.lastname: Einsiedel
authors.forename: Olivier
authors.initials: O
authors.lastname: Cassar
authors.forename: Peter
authors.initials: P
authors.lastname: Bardy
authors.forename: Daniel
authors.initials: D
authors.lastname: Kearney
authors.forename: Antoine
authors.initials: A
authors.lastname: Gessain
mesh_terms: D000368:Aged; D001315:Australia; D017809:Fatal Outcome; D005260:Female; D015368:Human T-lymphotropic virus 1 / Q000235:genetics*; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000175:diagnosis* / Q000821:virology; D008297:Male; D008875:Middle Aged; D058889:Molecular Typing; D010802:Phylogeny
keywords: ATLL; Australia; HTLV-1; adult T-cell leukemia/lymphoma; human T-cell lymphotropic virus type 1; indigenous Australians; molecular epidemiology; viruses
references.citation: Med J Aust. 1993 Jul 5;159(1):28-9
references.pmid: 8316109
references.citation: Med J Aust. 1993 Jul 5;159(1):12-6
references.pmid: 8316104
references.citation: Front Microbiol. 2012 Nov 15;3:388
references.pmid: 23162541
references.citation: Aust N Z J Med. 1991 Oct;21(5):739-41
references.pmid: 1759923
references.citation: Am J Clin Pathol. 1997 Jan;107(1):81-7
references.pmid: 8980372
references.citation: Lancet Infect Dis. 2007 Apr;7(4):266-81
references.pmid: 17376384
references.citation: J Virol. 1993 Feb;67(2):843-51
references.pmid: 8093491
references.citation: Clin Infect Dis. 2012 Jan 1;54(1):43-50
references.pmid: 22095566
references.citation: J Infect Dis. 2007 Aug 15;196(4):510-21
references.pmid: 17624835
references.citation: Leukemia. 2003 Jan;17(1):26-38
references.pmid: 12529656
references.citation: J Infect Dis. 2004 Nov 1;190(9):1605-9
references.pmid: 15478065
references.citation: Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7694-8
references.pmid: 1881912
references.citation: Med J Aust. 1988 Jul 18;149(2):104
references.pmid: 2839756