title: Skeletal muscle oxygen saturation (StO2) measured by near-infrared spectroscopy in the critically ill patients.
abstract: According to current critical care management guidelines, the overall hemodynamic optimization process seeks to restore macrocirculatory oxygenation, pressure, and flow variables. However, there is increasing evidence demonstrating that, despite normalization of these global parameters, microcirculatory and regional perfusion alterations might occur, and persistence of these alterations has been associated with worse prognosis. Such observations have led to great interest in testing new technologies capable of evaluating the microcirculation. Near-infrared spectroscopy (NIRS) measures tissue oxygen saturation (StO2) and has been proposed as a noninvasive system for monitoring regional circulation. The present review aims to summarize the existing evidence on NIRS and its potential clinical utility in different scenarios of critically ill patients.
authors.affiliation: Critical Care Department, Hospital de Sabadell, Corporació Sanitària Universitària Parc Taulí, Universitat Autònoma de Barcelona, 08208 Sabadell, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Mesquida
authors.forename: G
authors.initials: G
authors.lastname: Gruartmoner
authors.forename: C
authors.initials: C
authors.lastname: Espinal
mesh_terms: D016638:Critical Illness; D006801:Humans; D008833:Microcirculation / Q000502:physiology; D018482:Muscle, Skeletal / Q000187:drug effects / Q000378:metabolism*; D010100:Oxygen / Q000008:administration & dosage*; D019265:Spectroscopy, Near-Infrared
chemical_list: D010100:Oxygen
references.citation: J Trauma. 2006 Oct;61(4):780-8; discussion 788-90
references.pmid: 17033541
references.citation: J Trauma Acute Care Surg. 2012 Apr;72(4):930-5
references.pmid: 22491607
references.citation: J Emerg Trauma Shock. 2011 Apr;4(2):222-32
references.pmid: 21769210
references.citation: Intensive Care Med. 2012 Jun;38(6):976-83
references.pmid: 22527071
references.citation: J Trauma. 2005 Apr;58(4):806-13; discussion 813-6
references.pmid: 15824660
references.citation: Crit Care. 2009;13 Suppl 5:S13
references.pmid: 19951385
references.citation: Intensive Care Med. 2008 Sep;34(9):1600-7
references.pmid: 18523754
references.citation: New Horiz. 1996 Nov;4(4):420-5
references.pmid: 8968975
references.citation: Anesthesiology. 2005 Jul;103(1):25-32
references.pmid: 15983453
references.citation: Crit Care. 2011;15(5):R223
references.pmid: 21939529
references.citation: J Clin Monit Comput. 2013 Jun;27(3):215-21
references.pmid: 23381608
references.citation: Crit Care. 2010;14(2):R42
references.pmid: 20331856
references.citation: Intensive Care Med. 2011 Apr;37(4):671-7
references.pmid: 21253704
references.citation: Science. 1977 Dec 23;198(4323):1264-7
references.pmid: 929199
references.citation: Intensive Care Med. 2005 Dec;31(12):1661-8
references.pmid: 16205889
references.citation: Eur Respir J. 2014 Jan;43(1):213-20
references.pmid: 23314894
references.citation: Intensive Care Med. 2010 Nov;36(11):1813-25
references.pmid: 20689916
references.citation: Crit Care Med. 2011 Jul;39(7):1828-9
references.pmid: 21685748
references.citation: J Trauma. 2008 Apr;64(4):1010-23
references.pmid: 18404069
references.citation: J Trauma. 2007 Jan;62(1):44-54; discussion 54-5
references.pmid: 17215732
references.citation: Ann Intensive Care. 2012 May 08;2(1):11
references.pmid: 22569165
references.citation: J Trauma. 2001 Apr;50(4):629-34; discussion 634-5
references.pmid: 11303156
references.citation: Crit Care Clin. 1996 Oct;12(4):1019-29
references.pmid: 8902382
references.citation: Intensive Care Med. 2012 Apr;38(4):606-11
references.pmid: 22349421
references.citation: Intensive Care Med. 2012 Apr;38(4):592-7
references.pmid: 22310873
references.citation: Crit Care Med. 2013 Mar;41(3):791-9
references.pmid: 23318492
references.citation: J Trauma. 2009 Sep;67(3):441-3; discussion 443-4
references.pmid: 19741383
references.citation: Anesthesiology. 2009 Aug;111(2):366-71
references.pmid: 19602965
references.citation: Surg Infect (Larchmt). 2008 Oct;9(5):515-9
references.pmid: 18687043
references.citation: J Clin Monit Comput. 2012 Oct;26(5):361-6
references.pmid: 22833180
references.citation: Crit Care. 2009;13 Suppl 5:S3
references.pmid: 19951387
references.citation: Intensive Care Med. 2008 Dec;34(12):2210-7
references.pmid: 18594793
references.citation: J Appl Physiol (1985). 2008 Feb;104(2):475-81
references.pmid: 18006869
references.citation: Med Intensiva. 2011 Nov;35(8):499-508
references.pmid: 21208691
references.citation: J Trauma. 2000 Apr;48(4):637-42
references.pmid: 10780595
references.citation: Crit Care Med. 2011 Apr;39(4):695-701
references.pmid: 21220999
references.citation: Acta Physiol Scand. 2000 Apr;168(4):615-22
references.pmid: 10759598
references.citation: Shock. 1999 Sep;12(3):196-200
references.pmid: 10485597
references.citation: Intensive Care Med. 2006 Jan;32(1):87-92
references.pmid: 16261341
references.citation: Eur Heart J. 2010 Dec;31(24):3032-9
references.pmid: 20829210
references.citation: Am J Respir Crit Care Med. 2002 Jul 1;166(1):98-104
references.pmid: 12091178
references.citation: Crit Care Med. 2008 Jan;36(1):176-82
references.pmid: 18090350
references.citation: Crit Care Med. 2012 Feb;40(2):435-40
references.pmid: 22020233
references.citation: Crit Care Med. 1997 Jan;25(1):166-70
references.pmid: 8989194
references.citation: Lancet. 2002 May 25;359(9320):1812-8
references.pmid: 12044376
references.citation: J Appl Physiol (1985). 1994 Dec;77(6):2740-7
references.pmid: 7896615
references.citation: Intensive Care Med. 2010 Nov;36(11):1882-9
references.pmid: 20689910
references.citation: Intensive Care Med. 2009 Jun;35(6):1106-9
references.pmid: 19183952
references.citation: Surgery. 2004 Jun;135(6):662-70
references.pmid: 15179373
references.citation: Am Surg. 2008 Oct;74(10):1006-11
references.pmid: 18942633
references.citation: Am Surg. 2010 Dec;76(12):1384-92
references.pmid: 21265353
references.citation: Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H1065-71
references.pmid: 17483235
references.citation: J Biomed Opt. 2005 May-Jun;10(3):034017
references.pmid: 16229661
references.citation: J Trauma. 2010 Jul;69 Suppl 1:S14-25
references.pmid: 20622608
references.citation: Intensive Care Med. 2007 Sep;33(9):1549-56
references.pmid: 17572876
references.citation: Crit Care. 2009;13 Suppl 5:S6
references.pmid: 19951390
references.citation: Crit Care. 2007;11(1):R6
references.pmid: 17227587
references.citation: Shock. 2011 May;35(5):456-9
references.pmid: 21192279
references.citation: Shock. 2007 Apr;27(4):348-53
references.pmid: 17414414