title: In vivo antinuclear antibodies of the skin: A rare phenomenon on direct immunofluorescence.
abstract: Detection of immunoglobulins in epidermal cell nuclei or in vivo antinuclear antibodies on direct immunoflorescence microscopy of skin biopsies is an easily detectable immunopathologic feature. It is an unusual, but not totally rare, occurrence in systemic connective tissue disorders. This positive epidermal nuclear reaction is found to be commonly associated with immunoglobulin G.
authors.affiliation: PGIMER, Chandigarh, UT, India.
authors.forename: Seema
authors.initials: S
authors.lastname: Chhabra
authors.forename: Sandeep Kumar
authors.initials: SK
authors.lastname: Arora
authors.forename: Ranjana Walker
authors.initials: RW
authors.lastname: Minz
authors.forename: Suneel
authors.initials: S
authors.lastname: Dogra
mesh_terms: D000974:Antibodies, Antinuclear / Q000032:analysis* / Q000097:blood; D000918:Antibody Specificity; D001706:Biopsy; D002467:Cell Nucleus / Q000276:immunology; D003240:Connective Tissue Diseases / Q000276:immunology* / Q000473:pathology; D004817:Epidermis / Q000276:immunology*; D019085:Fluorescent Antibody Technique, Direct; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis / Q000097:blood; D012189:Retrospective Studies
chemical_list: D000974:Antibodies, Antinuclear; D007074:Immunoglobulin G