title: Antitumor and Antioxidant Activities of the Extracts from Fruiting Body of Phellinus linteus.
abstract: Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods. Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein contents were 6.2%, 21.8%, respectively. Amino acid pattern showed that two extracts contained large amount of aspartic acid and alanine. Two extracts showed characteristic IR absorption pattern for glycosidic bond at 890 cm(-1). PL-H was divided two fractions by gel filtration chromatography and the molecular weights of each fraction were estimated to be about 10 kD and 225 kD, respectively and also PL-A was estimated 10 kD. Two extracts showed strong antitumor, immunomodulating and antioxidant activities, and were compared with commercialized glycopeptide anticancer drugs.
authors.affiliation: Department of Food Processing and Cooking, Kyungbuk College, Yeongjusi 750-712, Korea.
authors.forename: June Woo
authors.initials: JW
authors.lastname: Lee
authors.forename: Seong Jin
authors.initials: SJ
authors.lastname: Baek
authors.forename: Woo Chul
authors.initials: WC
authors.lastname: Bae
authors.forename: Jeong Min
authors.initials: JM
authors.lastname: Park
authors.forename: Yong Seok
authors.initials: YS
authors.lastname: Kim
keywords: Antioxidant; Antitumor; Immunostimulation; Phellinus linteus; Polysaccharide
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