title: The regulation of cell size.
abstract: An adult animal consists of cells of vastly different size and activity, but the regulation of cell size remains poorly understood. Recent studies uncovering some of the signaling pathways important for size/growth control, together with the identification of diseases resulting from aberrations in these pathways, have renewed interest in this field. This Review will discuss our current understanding of how a cell sets its size, how it can adapt its size to a changing environment, and how these processes are relevant to human disease.
authors.affiliation: MRC Laboratory for Molecular Cell Biology and the UCL Cancer Institute, University College London, Gower Street, London WC1E 6BT, UK. Electronic address: alison.lloyd@ucl.ac.uk.
authors.forename: Alison C
authors.initials: AC
authors.lastname: Lloyd
mesh_terms: D000818:Animals; D002453:Cell Cycle; D049109:Cell Proliferation; D048429:Cell Size; D006706:Homeostasis; D006801:Humans; D009369:Neoplasms / Q000378:metabolism / Q000473:pathology; D009929:Organ Size; D015398:Signal Transduction