title: Alkoxide activation of aminoboranes towards selective amination.
abstract: Piece of the (inter)action: The interaction of alkoxides with the sp(2) Bpin (pin=pinacol) moiety in aminoboranes forms the in situ Lewis acid-base adduct [RO(-) →B(OR)2 N(R')2 ] which enables the amino moiety to react as a strong nucleophile with several electrophiles, thus providing amino alcohols, β-enamino esters, and β-hydroxy amides in a direct and remarkably selective way.
authors.affiliation: Department Química Física i Inorgànica, University Rovira i Virgili, C/Marcel lí Domingo s/n, 43007 Tarragona (Spain) http://www.quimica.urv.cat/tecat/catalytic_organoborane_chemistry.php.
authors.forename: Cristina
authors.initials: C
authors.lastname: Solé
authors.forename: Elena
authors.initials: E
authors.lastname: Fernández
keywords: Lewis acid; aminoboranes; diastereoselectivity; organocatalysis; synthetic methods