title: The impact of pre-operative weight loss on incidence of surgical site infection and readmission rates after total joint arthroplasty.
abstract: This study characterized a cohort of obese total hip arthroplasty (THA) and total knee arthroplasty (TKA) patients (1/1/2008-12/31/2010) and evaluated whether a clinically significant amount of pre-operative weight loss (5% decrease in body weight) is associated with a decreased risk of surgical site infections (SSI) and readmissions post-surgery. 10,718 TKAs and 4066 THAs were identified. During the one year pre-TKA 7.6% of patients gained weight, 12.4% lost weight, and 79.9% remained the same. In the one year pre-THA, 6.3% of patients gained weight, 18.0% lost weight, and 75.7% remained the same. In TKAs and THAs, after adjusting for covariates, the risk of SSI and readmission was not significantly different in the patients who gained or lost weight pre-operatively compared to those who remained the same.
authors.affiliation: Joint Doctoral Program Epidemiology, San Diego State University/University of California, San Diego, California.
authors.forename: Maria C S
authors.initials: MC
authors.lastname: Inacio
authors.affiliation: Department of Family and Preventive Medicine, University of California San Diego School of Medicine, San Diego California.
authors.forename: Donna
authors.initials: D
authors.lastname: Kritz-Silverstein
authors.affiliation: Department of Biostatistics, University of California San Diego School of Medicine, San Diego, California.
authors.forename: Rema
authors.initials: R
authors.lastname: Raman
authors.affiliation: Graduate School of Public Health, San Diego State University, San Diego, California.
authors.forename: Caroline A
authors.initials: CA
authors.lastname: Macera
authors.affiliation: School of Exercise & Nutritional Sciences, San Diego State University, San Diego, California.
authors.forename: Jeanne F
authors.initials: JF
authors.lastname: Nichols
authors.affiliation: Graduate School of Public Health, San Diego State University, San Diego, California.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Shaffer
authors.affiliation: Southern California Permanente Medical Group, Department of Orthopaedic Surgery, San Diego, California.
authors.forename: Donald C
authors.initials: DC
authors.lastname: Fithian
mesh_terms: D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D002140:California / Q000453:epidemiology; D015331:Cohort Studies; D015897:Comorbidity; D005260:Female; D006801:Humans; D015994:Incidence; D007592:Joint Diseases / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000453:epidemiology / Q000628:therapy; D010359:Patient Readmission / Q000706:statistics & numerical data; D057234:Preoperative Period; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control*; D016896:Treatment Outcome; D015431:Weight Loss
keywords: Total hip arthroplasty; Total knee arthroplasty; infection; obesity; readmission; weight loss