title: Preparation of non-heme {FeNO}7 models of cysteine dioxygenase: sulfur versus nitrogen ligation and photorelease of nitric oxide.
abstract: We present the synthesis and spectroscopic characterization of [Fe(NO)(N3PyS)]BF4 (3), the first structural and electronic model of NO-bound cysteine dioxygenase. The nearly isostructural all-N-donor analogue [Fe(NO)(N4Py)](BF4)2 (4) was also prepared, and comparisons of 3 and 4 provide insight regarding the influence of S vs N ligation in {FeNO}(7) species. One key difference occurs upon photoirradiation, which causes the fully reversible release of NO from 3, but not from 4.
authors.affiliation: Department of Chemistry, The Johns Hopkins University , Baltimore, Maryland 21218, United States.
authors.forename: Alison C
authors.initials: AC
authors.lastname: McQuilken
authors.forename: Yang
authors.initials: Y
authors.lastname: Ha
authors.forename: Kyle D
authors.initials: KD
authors.lastname: Sutherlin
authors.forename: Maxime A
authors.initials: MA
authors.lastname: Siegler
authors.forename: Keith O
authors.initials: KO
authors.lastname: Hodgson
authors.forename: Britt
authors.initials: B
authors.lastname: Hedman
authors.forename: Edward I
authors.initials: EI
authors.lastname: Solomon
authors.forename: Guy N L
authors.initials: GN
authors.lastname: Jameson
authors.forename: David P
authors.initials: DP
authors.lastname: Goldberg
mesh_terms: D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry* / Q000528:radiation effects; D050558:Cysteine Dioxygenase / Q000737:chemistry*; D008027:Light; D015394:Molecular Structure; D009569:Nitric Oxide / Q000737:chemistry*; D020030:Nitric Oxide Donors / Q000138:chemical synthesis / Q000737:chemistry* / Q000528:radiation effects; D013457:Sulfur Compounds / Q000737:chemistry*
chemical_list: D056831:Coordination Complexes; D020030:Nitric Oxide Donors; D013457:Sulfur Compounds; D009569:Nitric Oxide; D050558:Cysteine Dioxygenase
references.citation: J Am Chem Soc. 2007 Jun 13;129(23):7427-38
references.pmid: 17506560
references.citation: Dalton Trans. 2012 Jul 14;41(26):8047-59
references.pmid: 22653336
references.citation: J Am Chem Soc. 2009 Oct 7;131(39):13910-1
references.pmid: 19746912
references.citation: Biochemistry. 1992 May 19;31(19):4602-12
references.pmid: 1316153
references.citation: J Phys Chem A. 2012 Jan 12;116(1):582-91
references.pmid: 22091701
references.citation: Biochemistry. 2007 Jul 24;46(29):8569-78
references.pmid: 17602574
references.citation: Inorg Chem. 2011 Jan 17;50(2):427-36
references.pmid: 21158471
references.citation: J Am Chem Soc. 2009 Jun 24;131(24):8340-1
references.pmid: 19473015
references.citation: Biochim Biophys Acta. 2011 Dec;1814(12):2003-9
references.pmid: 21839860
references.citation: J Am Chem Soc. 2004 Apr 28;126(16):5138-53
references.pmid: 15099097
references.citation: J Am Chem Soc. 2011 Nov 16;133(45):18148-60
references.pmid: 21981763
references.citation: Chem Commun (Camb). 2012 Dec 21;48(98):11981-3
references.pmid: 23133836
references.citation: J Am Chem Soc. 2011 Feb 9;133(5):1274-7
references.pmid: 21207980
references.citation: Org Biomol Chem. 2012 Jul 28;10(28):5401-9
references.pmid: 22714822
references.citation: Chem Rev. 2002 Apr;102(4):993-1018
references.pmid: 11942785
references.citation: J Am Chem Soc. 2011 Feb 9;133(5):1419-27
references.pmid: 21207999
references.citation: J Am Chem Soc. 2004 Jan 21;126(2):505-15
references.pmid: 14719948
references.citation: Inorg Chem. 2003 Oct 20;42(21):6812-23
references.pmid: 14552634
references.citation: Inorg Chem. 2009 Oct 5;48(19):9104-11
references.pmid: 19722518
references.citation: J Am Chem Soc. 2012 May 30;134(21):8758-61
references.pmid: 22578255
references.citation: Biochemistry. 2012 Jan 10;51(1):257-64
references.pmid: 22122511
references.citation: Angew Chem Int Ed Engl. 2012 Feb 27;51(9):2234-7
references.pmid: 22287034
references.citation: J Inorg Biochem. 2013 May;122:1-7
references.pmid: 23416309
references.citation: Biochemistry. 2011 Nov 29;50(47):10241-53
references.pmid: 21992268
references.citation: J Am Chem Soc. 2011 Mar 23;133(11):3869-82
references.pmid: 21344861
references.citation: Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3796-801
references.pmid: 12655067
references.citation: J Am Chem Soc. 2004 Sep 8;126(35):10867-74
references.pmid: 15339171
references.citation: Inorg Chem. 2002 Jul 1;41(13):3444-56
references.pmid: 12079463
references.citation: J Am Chem Soc. 2010 Sep 8;132(35):12214-5
references.pmid: 20712312
references.citation: Chem Rev. 2004 Feb;104(2):939-86
references.pmid: 14871146
references.citation: Chem Rev. 2004 Feb;104(2):403-18
references.pmid: 14871130
references.citation: Biochemistry. 2008 Nov 4;47(44):11390-2
references.pmid: 18847220
references.citation: Dalton Trans. 2012 Aug 28;41(36):10883-99
references.pmid: 22814765
references.citation: Angew Chem Int Ed Engl. 2002 Jul 15;41(14):2512-5
references.pmid: 12203518
references.citation: Inorg Chem. 2010 Jul 19;49(14):6293-316
references.pmid: 20666388
references.citation: Inorg Chem. 2010 Feb 15;49(4):1854-64
references.pmid: 20067276
references.citation: J Am Chem Soc. 2012 Jul 11;134(27):11112-5
references.pmid: 22713134