title: Secondary hypertension and hirsutism as a clinical manifestation of tumor duplicity.
abstract: BACKGROUND
  The differential diagnosis of the pathogenetic causes of hirsutism in combination with hypertension is a challenge for clinicians.
  
  
  RESULTS
  This case report demonstrates a patient suffering from two hormonally active tumors - an adrenal adenoma with primary aldosteronism and a Leydig cell ovarian tumor with hyperandrogenism. The task of the authors was easier due to the perimenopausal age of the proband. Adrenal selective venous sampling was very helpful in the diagnosis of these active endocrine tumors. Both were resolved by a single laparoscopic surgery.
  
  
  CONCLUSIONS
  The combination of the two described tumors is a unique clinical finding. The resolution using laparoscopy in a single procedure provided an elegant and efficient therapeutic approach.
authors.affiliation: Department of Internal Medicine III - Nephrology, Rheumatology and Endocrinology, University Hospital Olomouc, Czech Republic.
authors.forename: Zdenek
authors.initials: Z
authors.lastname: Frysak
authors.forename: David
authors.initials: D
authors.lastname: Karasek
authors.forename: Igor
authors.initials: I
authors.lastname: Hartmann
authors.forename: Ladislava
authors.initials: L
authors.lastname: Kucerova
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006628:Hirsutism / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000209:etiology*; D007984:Leydig Cell Tumor / Q000150:complications* / Q000175:diagnosis; D010051:Ovarian Neoplasms / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed