title: The Genomic Blueprint of Salmonella enterica subspecies enterica serovar Typhi P-stx-12.
abstract: Salmonella enterica subspecies enterica serovar Typhi is a rod-shaped, Gram-negative, facultatively anaerobic bacterium. It belongs to the family Enterobacteriaceae in the class Gammaproteobacteria, and has the capability of residing in the human gallbladder by forming a biofilm and hence causing the person to become a typhoid carrier. Here we present the complete genome of Salmonella enterica subspecies enterica serotype Typhi strain P-stx-12, which was isolated from a chronic carrier in Varanasi, India. The complete genome comprises a 4,768,352 bp chromosome with a total of 98 RNA genes, 4,691 protein-coding genes and a 181,431 bp plasmid. Genome analysis revealed that the organism is closely related to Salmonella enterica serovar Typhi strain Ty2 and Salmonella enterica serovar Typhi strain CT18, although their genome structure is slightly different.
authors.affiliation: Centre for Chemical Biology, Universiti Sains Malaysia, Penang, Malaysia.
authors.forename: Su Yean
authors.initials: SY
authors.lastname: Ong
authors.forename: Chandra Bhan
authors.initials: CB
authors.lastname: Pratap
authors.forename: Xuehua
authors.initials: X
authors.lastname: Wan
authors.forename: Shaobin
authors.initials: S
authors.lastname: Hou
authors.forename: Ahmad Yamin Abdul
authors.initials: AY
authors.lastname: Rahman
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Saito
authors.forename: Gopal
authors.initials: G
authors.lastname: Nath
authors.forename: Maqsudul
authors.initials: M
authors.lastname: Alam
keywords: Enterobacteriaceae; Gram-negative; Salmonella; Typhi; Typhoid Fever; host-specific; pathogen
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