title: Effect of partial weight-supported treadmill gait training on balance in patients with Parkinson disease.
abstract: OBJECTIVE
  To investigate the role of conventional gait training and partial weight-supported treadmill gait training (PWSTT) in improving the balance of patients with Parkinson disease (PD).
  
  
  METHODS
  Prospective randomized controlled design.
  
  
  METHODS
  National-level university tertiary hospital for mental health and neurosciences.
  
  
  METHODS
  Sixty patients with PD fulfilling the United Kingdom Brain Bank PD diagnostic criteria were recruited from the neurology outpatient department and movement disorder clinic.
  
  
  METHODS
  The patients were randomly assigned into 3 equal groups: (1) a control group that only received a stable dosage of dopaminomimetic drugs; (2) a conventional gait training (CGT) group that received a stable dosage of dopaminomimetic drugs and conventional gait training; and (3) a PWSTT group that received a stable dosage of dopaminomimetic drugs and PWSTT with unloading of 20% of body weight. The sessions for the CGT and PWSTT groups were provided for 30 minutes per day, 4 days per week, for 4 weeks (16 sessions).
  
  
  METHODS
  The Unified Parkinson Disease Rating Scale (UPDRS) motor score, dynamic posturography, Berg Balance Scale, and Tinetti performance-oriented mobility assessment (POMA) were used as main outcome measures.
  
  
  RESULTS
  A significant interaction effect was observed in the UPDRS motor score, mediolateral index, Berg Balance Scale, limits of stability (LOS) total score, POMA gait score, and balance score. Post-hoc analysis showed that in comparison with the control group, the PWSTT group had a significantly better UPDRS motor score, balance indices, LOS in 8 directions, POMA gait, and balance score. The CGT group had a significantly better POMA gait score compared with control subjects. Compared with the CGT group, the PWSTT group had a significantly better UPDRS motor score, mediolateral index, POMA gait score, and LOS total score.
  
  
  CONCLUSIONS
  PWSTT may be a better interventional choice than CGT for gait and balance rehabilitation in patients with PD.
authors.affiliation: Department of Neurophysiology, National Institute of Mental Health & Neurosciences, Bangalore, India; currently at Department of Physical Therapy, University of Illinois, Chicago, IL(∗).
authors.forename: Mohan
authors.initials: M
authors.lastname: Ganesan
authors.affiliation: Department of Neurophysiology, National Institute of Mental Health & Neurosciences, Bangalore, India(†).
authors.forename: Talakad N
authors.initials: TN
authors.lastname: Sathyaprabha
authors.affiliation: Neurological Rehabilitation, National Institute of Mental Health & Neurosciences, Bangalore, India(‡).
authors.forename: Anupam
authors.initials: A
authors.lastname: Gupta
authors.affiliation: Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore 560029, India(§). Electronic address: palpramod@hotmail.com.
authors.forename: Pramod Kumar
authors.initials: PK
authors.lastname: Pal
mesh_terms: D000704:Analysis of Variance; D015259:Dopamine Agents / Q000627:therapeutic use; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D020233:Gait Disorders, Neurologic / Q000503:physiopathology / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy / Q000503:physiopathology / Q000534:rehabilitation*; D004856:Postural Balance / Q000502:physiology*; D011446:Prospective Studies
chemical_list: D015259:Dopamine Agents