title: Low-dose mirtazapine in treatment of major depression developed following severe nausea and vomiting during pregnancy: two cases.
abstract: This report presents the successful use of low-dose mirtazapine in the treatment of major depression that developed following severe nausea and vomiting symptoms during the early gestational weeks in two cases. The psychiatric diagnosis was determined with the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Assessments were performed with the Clinical Global Impression-Improvement Scale and the 17-item Hamilton Rating Scale for Depression. Further large-scale studies should be carried out to confirm the useful effects observed in these cases.
authors.affiliation: Department of Psychiatry, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey. Electronic address: farukuguz@gmail.com.
authors.forename: Faruk
authors.initials: F
authors.lastname: Uguz
mesh_terms: D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D003865:Major Depressive Disorder / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000150:complications*; D008803:Mianserin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000078785:Mirtazapine; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000929:Antidepressive Agents, Tricyclic; D008803:Mianserin; D000078785:Mirtazapine
keywords: Antidepressants; Mirtazapine; Pregnancy; Women