title: [Septal alcohol ablation in patients with hypertrophic cardiomyopathy].
abstract: OBJECTIVE
  to know the clinical and hemodynamic course in septal obstructive hypertrophic cardiomyopathy (SOHC) after alcohol ablation.
  
  
  METHODS
  this was an observational, longitudinal study, including 21 patients with SOHC with functional class of the New York Heart Association (CF-NYHA) refractory to treatment and/or = 30 mm Hg gradient at rest or = 60 mm Hg provoked, or have systolic anterior motion or mitral incompetence (MI) > grade II by echocardiography.
  
  
  RESULTS
  average age was 50 ± 16 years, males 38.1 %, females 61.9 %; symptoms: angina 42.9 %, dyspnea 85.7 %, syncope 23.8 %. Pre-ablation CF-NYHA was III and IV in 61.9 %; after a year follow-up all of them were class I-II. Pre-ablation, after and one year later, interventricle septum measures were 22.7 ± 4.9 and 20.7 ± 3.1 mm; left ventricular ejection fraction was 65.5 ± 7 %, 62.2 % ± 6.5 % and 68.7 ± 6.2 %; the output gradient of the left ventricle were 106.9 ± 29.9, 44.6 ± 24.3 and 22.0 ± 5.7 mm Hg. Pre-ablation MI grade-III and IV were 33.3 % and 47.6 %; after a year it was grade-0, 52.4 %, grade-I 28.6 %, grade-II, 19 %. There were no hospital mortality.
  
  
  CONCLUSIONS
  the alcohol septal ablation in SOHC patients had a high success treatment with a low complication rate.
authors.affiliation: Hospital de Cardiología, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, Mexico.
authors.forename: Gustavo
authors.initials: G
authors.lastname: López-Aburto
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Palacios-Rodríguez
authors.forename: Samuel
authors.initials: S
authors.lastname: Cantú-Ramírez
authors.forename: Eduardo
authors.initials: E
authors.lastname: Galván-García
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Tolosa-Dzul
authors.forename: Armando
authors.initials: A
authors.lastname: Morán-Benavente
authors.forename: Raúl
authors.initials: R
authors.lastname: Ontiveros-Martínez
mesh_terms: D055011:Ablation Techniques; D002312:Cardiomyopathy, Hypertrophic / Q000628:therapy*; D000431:Ethanol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D000431:Ethanol
keywords: ablation techniques; cardiomiopatía hipertrófica; etanol; ethanol; hypertrophic cardiomyopathy; técnicas de ablación