title: The redox-neutral approach to C-H functionalization.
abstract: The direct functionalization of C-H bonds is an attractive strategy in organic synthesis. Although several advances have been made in this area, the selective activation of inert sp(3) C-H bonds remains a daunting challenge. Recently, a new type of sp(3) C-H activation mode through internal hydride transfer has demonstrated the potential to activate remote sp(3) C-H linkages in an atom-economic manner. This Minireview attempts to classify recent advances in this area including the transition to non-activated sp(3) C-H bonds and asymmetric hydride transfers.
authors.affiliation: Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470 Mülheim an der Ruhr (Germany), Fax: (+49) 2083062974.
authors.forename: Bo
authors.initials: B
authors.lastname: Peng
authors.forename: Nuno
authors.initials: N
authors.lastname: Maulide
keywords: CH activation; CH functionalization; atom economy; hydride transfer; redox chemistry