title: A new strategy for designing a graphene oxide-based DNA hairpin probe: fluorescence upon switching the orientation of the sticky end.
abstract: Here we report a new strategy for designing a graphene oxide (GO)-quenched dye-labeled DNA hairpin probe by utilizing the sticky end adsorbed onto the GO surface. Only introduction of target DNA can alter the orientation of the sticky end, causing the dye to move apart from the GO surface, resulting in fluorescence restoration.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, Key Laboratory for Bio-Nanotechnology and Molecule Engineering of Hunan Province, Hunan University, Changsha 410082, P. R. China. kmwang@hnu.edu.cn.
authors.forename: Jin
authors.initials: J
authors.lastname: Huang
authors.forename: Xiaohai
authors.initials: X
authors.lastname: Yang
authors.forename: Xiaoxiao
authors.initials: X
authors.lastname: He
authors.forename: Kemin
authors.initials: K
authors.lastname: Wang
authors.forename: Yong
authors.initials: Y
authors.lastname: He
authors.forename: Ke
authors.initials: K
authors.lastname: Quan
mesh_terms: D004247:DNA / Q000737:chemistry*; D015342:DNA Probes / Q000737:chemistry*; D005453:Fluorescence; D006108:Graphite / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D015342:DNA Probes; D010087:Oxides; D006108:Graphite; D004247:DNA