title: Comparison of Saliva-Check Mutans and Saliva-Check IgA Mutans with the Cariogram for caries risk assessment.
abstract: The purpose of the study was to evaluate the combined use of two rapid, semiquantitative detection kits (Saliva-Check Mutans and Saliva-Check IgA Mutans) to assess caries risk using the Cariogram computer-based program as a reference method. Stimulated saliva samples were collected from 71 subjects, 20-73 yr of age, and the number of Streptococcus mutans per ml of saliva was measured using Saliva-Check Mutans. After 15 min, a red line in the test detection window indicated >5 × 10(5) colony-forming units (CFU) of S. mutans per ml of saliva. The concentration of salivary IgA in relation to the number of mutans streptococci was examined using the Saliva-Check IgA Mutans test kit. The presence or absence of a red line after 15 min indicated a high or a low concentration of IgA, respectively. By combining the results obtained from these two test systems, each patient was classified into one of four groups of low to high caries risk. Compared with the Cariogram data, the combined results of both detection kits showed that 39 (95%) of 41 subjects had a high chance of avoiding caries and 20 (67%) of 30 subjects had a low chance. The data suggest that the combination of Saliva-Check Mutans and Saliva-Check IgA Mutans could be used for caries risk assessment.
authors.affiliation: Department of Cariology, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
authors.forename: Kerstin
authors.initials: K
authors.lastname: Wennerholm
authors.forename: Claes-Göran
authors.initials: CG
authors.lastname: Emilson
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D003731:Dental Caries / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D018570:Risk Assessment / Q000379:methods*; D012463:Saliva / Q000737:chemistry / Q000382:microbiology*; D012984:Software; D013295:Streptococcus mutans / Q000302:isolation & purification*
chemical_list: D007070:Immunoglobulin A
keywords: Cariogram; Saliva-Check IgA Mutans; Saliva-Check Mutans; caries risk assessment