title: Evaluation of a novel automated non-invasive pulse pressure variation algorithm.
abstract: In mechanically ventilated patients, Pulse Pressure Variation (PPV) has been shown to be a useful parameter to guide fluid management. We evaluated a real-time automated PPV-algorithm by comparing it to manually calculated PPV-values. In 10 critically ill patients, blood pressure was measured invasively (IBP) and non-invasively (CNAP(®) Monitor, CNSystems Medizintechnik, Austria). PPV was determined manually and compared to automated PPV values: PPVmanIBP vs. PPVautoIBP was -0.19 ± 1.65% (mean bias ± standard deviation), PPVmanCNAP vs. PPVautoCNAP was -1.02 ± 2.03% and PPVautoCNAP vs. PPVmanIBP was -2.10 ± 3.14%, suggesting that the automated CNAP(®) PPV-algorithm works well on both blood pressure waveforms but needs further clinical evaluation.
authors.affiliation: Institute for Medical Engineering, University of Technology Graz, Austria.
authors.forename: Martin
authors.initials: M
authors.lastname: Schmid
authors.forename: Helga
authors.initials: H
authors.lastname: Prettenthaler
authors.forename: Christian
authors.initials: C
authors.lastname: Weger
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Smolle
mesh_terms: D000328:Adult; D000465:Algorithms; D001331:Automation / Q000295:instrumentation / Q000379:methods; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination / Q000295:instrumentation / Q000379:methods*; D016638:Critical Illness; D005260:Female; D005385:Fingers / Q000098:blood supply / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results; D012121:Respiration, Artificial; D012815:Signal Processing, Computer-Assisted
keywords: CNAP(®) Monitor 500; Continuous non-invasive arterial blood pressure monitoring; Fluid management; Mechanical ventilation; Pulse pressure variation; Vascular unloading