title: Determination of L-argininamide based on water-soluble fluorescent conjugated polymer-aptamer.
abstract: Water-soluble fluorescent conjugated polymer is a promising material which could be used as an optical platform in highly sensitive molecular sensors. In this paper, a simple label-free DNA sensor, which consisted of a poly(3-alkoxy-4-methylthiophene) and an aptamer, was used to detect L-argininamide (L-Arm). Due to the specific binding reaction between L-Arm and its aptamer, the proposed method can easily determinate the L-Arm through the recovery of fluorescence without any modification. Other ions or similar molecules had little effect on the detection. Moreover, there was a linear relationship between fluorescence intensity and the concentration of L-Arm. The detection limit of L-Arm was as low as 4.7 nM.
authors.affiliation: School of Environment and Civil Engineering, Wuhan Institute of Technology, Wuhan 430074, China.
authors.forename: Hongliang
authors.initials: H
authors.lastname: Guan
authors.forename: Zhike
authors.initials: Z
authors.lastname: He
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