title: Increased ion conductance across mammalian membranes modified with conjugated oligoelectrolytes.
abstract: Variation in conjugated oligoelectrolyte (COE) repeat units is shown to affect the rate of COE insertion into mammalian membrane patches and membrane patch stabilities. These findings suggest that it is possible to find COE structures that do not destroy membranes while at the same time allow for more facile transmembrane movement of ions/substrates.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.
authors.forename: Jenny
authors.initials: J
authors.lastname: Du
authors.forename: Alexander W
authors.initials: AW
authors.lastname: Thomas
authors.forename: Xiaofen
authors.initials: X
authors.lastname: Chen
authors.forename: Logan E
authors.initials: LE
authors.lastname: Garner
authors.forename: Carol A
authors.initials: CA
authors.lastname: Vandenberg
authors.forename: Guillermo C
authors.initials: GC
authors.lastname: Bazan
mesh_terms: D000818:Animals; D019556:COS Cells; D002462:Cell Membrane / Q000378:metabolism*; D002522:Chlorocebus aethiops; D004573:Electrolytes / Q000737:chemistry / Q000378:metabolism*; D017136:Ion Transport; D007477:Ions / Q000378:metabolism*; D011145:Polyvinyls / Q000737:chemistry / Q000378:metabolism*
chemical_list: D004573:Electrolytes; D007477:Ions; D011145:Polyvinyls; C530822:oligo(p-phenylene vinylene)