title: Comment on "Influence of HLA-C expression level on HIV control".
abstract: Apps et al. (Reports, 5 April 2013, p. 87) found that high human leukocyte antigen C (HLA-C) expression favors HIV-1 control. However, as noted here, HLA-C was assessed with a monoclonal antibody (DT9) that cross-reacts with HLA-E. In the context of the available evidence, this is consistent with the idea that the two leukocyte antigens collaborate to keep the HIV-1 virus at bay.
authors.affiliation: Istituto Nazionale Tumori Regina Elena, Via delle Messi d'Oro 156, 00158 Roma, Italy.
authors.forename: Elisa
authors.initials: E
authors.lastname: Lo Monaco
authors.forename: Elisa
authors.initials: E
authors.lastname: Tremante
authors.forename: Priscilla
authors.initials: P
authors.lastname: Biswas
authors.forename: Martin P
authors.initials: MP
authors.lastname: Cranage
authors.forename: Donato
authors.initials: D
authors.lastname: Zipeto
authors.forename: Alberto
authors.initials: A
authors.lastname: Beretta
authors.forename: Patrizio
authors.initials: P
authors.lastname: Giacomini
mesh_terms: D005786:Gene Expression Regulation; D006678:HIV / Q000276:immunology*; D015658:HIV Infections / Q000235:genetics* / Q000276:immunology*; D015236:HLA-C Antigens / Q000235:genetics*; D006801:Humans; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*
chemical_list: D015236:HLA-C Antigens