title: Synergistic growth effect among bacteria recovered from root canal infections.
abstract: The objective of this study was to determine the ecological relationships between bacterial species that colonize infected root canals. Root canal bacteria recovered from one patient with pulp canal necrosis were evaluated in vitro for synergistic and antagonistic activities determined by mono and co-culture growth kinetics and the production of bacteriocin-like substances using the double layer diffusion method. Peptostreptococcus prevotii triggered a significant increase of Fusobacterium nucleatum growth, while the former bacteria did not affect the growth of P. prevotii. The bacterial species did not produce antagonism activity against itself or against any of the other two species. Despite many studies have demonstrated the capability of root canal microorganisms to produce antagonistic substances, these in vitro experimental tests show the synergistic effect of P. prevotii on the growth of F. nucleatum.
authors.affiliation: Faculdade de Odontologia, Universidade de Itaúna , Itaúna, MG , Brasil.
authors.forename: Gil
authors.initials: G
authors.lastname: Moreira Júnior
authors.forename: Antônio Paulino
authors.initials: AP
authors.lastname: Ribeiro Sobrinho
authors.forename: Bernardo Henrique Silva
authors.initials: BH
authors.lastname: Bambirra
authors.forename: Felipe Henrique Silva
authors.initials: FH
authors.lastname: Bambirra
authors.forename: Maria Auxiliadora Roque
authors.initials: MA
authors.lastname: Carvalho
authors.forename: Luiz Macedo
authors.initials: LM
authors.lastname: Farias
authors.forename: Jacques Robert
authors.initials: JR
authors.lastname: Nicoli
authors.forename: Elizabeth Spangler
authors.initials: ES
authors.lastname: Moreira
keywords: Root canal; bacterial relationships; infection
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