title: Adherence in adults with type 1 diabetes mellitus correlates with treatment satisfaction but not with adverse events.
abstract: OBJECTIVE
  Diabetes self-care and self-monitoring adherence has a positive effect on the metabolic control of the disease. The aim of this study was to analyze the adherence to self-care recommendations and to identify its correlates in adults with type 1 diabetes mellitus.
  
  
  METHODS
  One hundred and eleven patients with type 1 diabetes were enrolled in an observational cross-sectional study conducted at the Diabetes Center of the University Hospital in Hradec Králové, Czech Republic. Diabetes self-care adherence was measured by the Self Care Inventory-Revised, and treatment satisfaction by the Diabetes Treatment Satisfaction Questionnaire-status version. Additional data were collected from self-administered questionnaires and medical records. The Mann-Whitney test, Spearman correlations, and multiple linear regressions were used in the statistical analysis.
  
  
  RESULTS
  The mean age of patients was 42.4 years; 59.5% of them were females and 53.2% of all patients used an insulin pump. The mean glycosylated hemoglobin (HbA1c) was 66.2 ± 15.3 mmol/mol and the mean insulin dosage was 0.6 ± 0.3 IU insulin/kg/day. The number of hypoglycemic episodes (including severe) that patients had in the last month before taking the survey was 3.6 ± 3.2. Self-care adherence was associated with treatment satisfaction (0.495; P = 0.004) along with frequency of self-monitoring of before meal blood glucose (0.267; P = 0.003). It was not associated with the incidence of hypoglycemic events or any other insulin therapy-related problems or with socio-demographic or clinical characteristics.
  
  
  CONCLUSIONS
  Treatment satisfaction is one of the key factors that need to be targeted to maximize benefits to patients. Self-care adherence in adults with type 1 diabetes did not correlate with socio-demographic and clinical characteristics, nor with adverse events.
authors.affiliation: Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Hradec Králové, Czech Republic.
authors.forename: Tereza
authors.initials: T
authors.lastname: Hendrychova
authors.forename: Magda
authors.initials: M
authors.lastname: Vytrisalova
authors.forename: Alena
authors.initials: A
authors.lastname: Smahelova
authors.forename: Jiri
authors.initials: J
authors.lastname: Vlcek
authors.forename: Ales Antonin
authors.initials: AA
authors.lastname: Kubena
keywords: diabetes treatment satisfaction questionnaire; self-care inventory revised; self-monitoring; treatment adherence
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