title: [Radionuclide imaging of neurendocrine tumors: biological basis and diagnostic results].
abstract: Many radiopharmaceuticals have been successfully used in nuclear medicine to detect neuroendocrine tumors, and many of them are based on a specific mechanism of uptake, while others are non-specific probes. This "review" focuses on the clinical applications of metaiodobenzylguanidine, (111)In-pentreotide and positron emission tomography (PET) tracers. New avances in diagnostic imaging will be discussed. Molecular imaging serves these diagnostic functions and provides powerful means for non-invasively detecting disease.
authors.forename: Eugenio Annibale
authors.initials: EA
authors.lastname: Genovese
authors.forename: Vania
authors.initials: V
authors.lastname: Mallardo
authors.forename: Michele
authors.initials: M
authors.lastname: Rossi
authors.forename: Andrea
authors.initials: A
authors.lastname: Vaccaro
authors.forename: Antonio
authors.initials: A
authors.lastname: Raucci
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Della Vecchi
authors.forename: Giovanna
authors.initials: G
authors.lastname: Romano
authors.forename: Teresa
authors.initials: T
authors.lastname: Califano
authors.forename: Francesco
authors.initials: F
authors.lastname: Schillirò
mesh_terms: D019797:3-Iodobenzylguanidine / Q000493:pharmacokinetics; D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging; D014408:Biomarkers, Tumor / Q000032:analysis; D018276:Carcinoma, Medullary / Q000000981:diagnostic imaging; D005770:Gastrointestinal Neoplasms / Q000000981:diagnostic imaging; D006801:Humans; D007457:Iodine Radioisotopes; D018358:Neuroendocrine Tumors / Q000737:chemistry / Q000000981:diagnostic imaging*; D010673:Pheochromocytoma / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D017481:Receptors, Somatostatin / Q000032:analysis; D012680:Sensitivity and Specificity; D013004:Somatostatin / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000502:physiology; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods
chemical_list: D014408:Biomarkers, Tumor; D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin; D019797:3-Iodobenzylguanidine; D013004:Somatostatin; C081788:pentetreotide