title: Stroke: a new CHANCE for combination antiplatelet therapy?
abstract: Patients with transient ischaemic attack or minor ischaemic stroke have a high risk of early recurrence. A new study in Chinese patients suggests that this risk is reduced following treatment with clopidogrel plus aspirin compared with aspirin alone. However, whether the findings can be extrapolated to other populations remains unclear.
authors.affiliation: Department of Neurology and Stroke Centre, University Duisburg-Essen, Hufelandstrasse 55, 45147 Essen, Germany.
authors.forename: Hans-Christoph
authors.initials: HC
authors.lastname: Diener
authors.forename: Christian
authors.initials: C
authors.lastname: Weimar
mesh_terms: D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000188:drug therapy*; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D020521:Stroke / Q000188:drug therapy*; D013988:Ticlopidine / Q000031:analogs & derivatives*
chemical_list: D010975:Platelet Aggregation Inhibitors; D013988:Ticlopidine
references.citation: N Engl J Med. 2013 Jul 4;369(1):11-9
references.pmid: 23803136
references.citation: Curr Clin Pharmacol. 2007 Jan;2(1):93-109
references.pmid: 18690857
references.citation: Lancet. 2007 Oct 20;370(9596):1432-42
references.pmid: 17928046
references.citation: Circulation. 2005 May 3;111(17):2233-40
references.pmid: 15851601
references.citation: Int J Stroke. 2015 Jul;10(5):686-91
references.pmid: 23692560
references.citation: Lancet Neurol. 2007 Nov;6(11):953-60
references.pmid: 17928270
references.citation: N Engl J Med. 2012 Aug 30;367(9):817-25
references.pmid: 22931315
references.citation: Lancet. 2004 Jul 24-30;364(9431):331-7
references.pmid: 15276392
references.citation: N Engl J Med. 2006 Apr 20;354(16):1706-17
references.pmid: 16531616
references.citation: Stroke. 2012 Apr;43(4):1058-66
references.pmid: 22282894