title: Electron paramagnetic resonance study of tumor affected bone marrow.
abstract: To study the mechanism of interaction of tumor cells with bone marrow cells continuous wave electron paramagnetic resonance (EPR) experiments at 9 GHz including a spin trapping of superoxide were carried out. The common features of the EPR spectra in healthy and tumor affected tissues of donors and rats as well as their difference are presented and discussed. It is proposed that labile iron pool plays a significant role in mechanisms of tumor invasion. We hope that the observed EPR features could be used to study the mechanisms of invasion and progression of tumor in different organs.
authors.affiliation: R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine, Kiev, Ukraine.
authors.forename: A P
authors.initials: AP
authors.lastname: Burlaka
authors.forename: I I
authors.initials: II
authors.lastname: Ganusevich
authors.forename: M R
authors.initials: MR
authors.lastname: Gafurov
authors.forename: S N
authors.initials: SN
authors.lastname: Lukin
authors.forename: E P
authors.initials: EP
authors.lastname: Sidorik
references.citation: Nat Rev Cancer. 2013 May;13(5):342-55
references.pmid: 23594855
references.citation: Nat Rev Mol Cell Biol. 2007 Oct;8(10):813-24
references.pmid: 17848967
references.citation: NMR Biomed. 2004 Aug;17(5):335-51
references.pmid: 15366033
references.citation: Phys Med Biol. 1969 Jul;14(3):373-96
references.pmid: 4307051
references.citation: Stem Cells. 2001;19(3):219-25
references.pmid: 11359947