title: [Thrombosis risk during pregnancy after history of cerebral venous thrombosis].
abstract: BACKGROUND
  Few data have been published about the prognosis of a pregnancy following an episode of venous cerebral thrombosis (CVT), and far less about preventive strategy.
  
  
  METHODS
  This is a retrospective study of a case series of 11 pregnancies in six women who had previously presented a CVT.
  
  
  RESULTS
  The first pregnancies after CVT occurred on average 58 months later. Prevention with aspirin or heparin was administered in ten cases during pregnancy, and in all the cases with heparin in postpartum. No recurrence of CVT was observed. A minor pulmonary embolism was diagnosed in postpartum in one case.
  
  
  CONCLUSIONS
  Prognosis of a pregnancy after a CVT seems to be favourable if a sufficient delay after CVT is respected. Although no results of controlled trials are available, prophylaxis with heparin is probably reasonable as benefit seems higher than risks and is strongly advised during the postpartum period.
authors.affiliation: Consultation de médecine interne, service de réanimation médicale et médecine interne, université de Poitiers, CHU de Poitiers, 2, rue de la Milétrie, BP 577, 86021 Poitiers, France. Electronic address: o.pourrat@chu-poitiers.fr.
authors.forename: O
authors.initials: O
authors.lastname: Pourrat
authors.affiliation: Service de neurologie, université de Poitiers, CHU de Poitiers, 2, rue de la Milétrie, BP 577, 86021 Poitiers, France.
authors.forename: J-P
authors.initials: JP
authors.lastname: Neau
authors.affiliation: Fédération de médecine interne, centre hospitalier Georges-Renon, 79021 Niort, France.
authors.forename: J-F
authors.initials: JF
authors.lastname: Pouget-Abadie
authors.affiliation: Service de gynécologie obstétrique, université de Poitiers, CHU de Poitiers, 2, rue de la Milétrie, BP 577, 86021 Poitiers, France.
authors.forename: F
authors.initials: F
authors.lastname: Pierre
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D018890:Chemoprevention; D005192:Family Health / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D020767:Intracranial Thrombosis / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D013927:Thrombosis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D055815:Young Adult
chemical_list: D000925:Anticoagulants; D001241:Aspirin
keywords: Accident vasculaire cérébral; Antithrombotics; Antithrombotiques; Cerebral venous thrombosis; Grossesse à risque; High-risk pregnancy; Stroke; Thrombophilia; Thrombophilie; Thrombophlébite cérébrale; Thrombose veineuse cérébrale