title: Weight loss is more important than the diet type in improving adiponectin levels among overweight/obese adults.
abstract: OBJECTIVE
  The study objective was to compare the effect of a standard calorie- and fat-restricted diet (STD-D) and a calorie- and fat-restricted lacto-ovo-vegetarian diet (LOV-D) on total and high-molecular-weight (HMW) adiponectin levels after 6 months of behavioral intervention.
  
  
  METHODS
  This study is an ancillary study to a randomized clinical trial.
  
  
  METHODS
  Subjects included 143 overweight/obese adults (STD-D = 79; LOV-D = 64).
  
  
  METHODS
  Both groups received the same standard behavioral intervention; the only difference was that LOV-D participants were instructed to eliminate meat, poultry, and fish from their diet.
  
  
  METHODS
  Weight, dietary intake with the 3-day food diary, and total and HMW adiponectin levels were measured.
  
  
  RESULTS
  Both groups significantly increased total (STD-D +7.2 ± 17.8%; LOV-D +9.4 ± 21.8%) and HMW adiponectin levels (STD-D +18.5 ± 32.9%; LOV-D +15.8 ± 34.5%; ps < 0.05) with no significant differences between the groups. We found significant associations between weight loss and increases in total (β (SE) = -.071(.27); p = 0.003) and HMW adiponectin (β (SE) = -1.37(.47); p = 0.001) levels independent of the diet type. Weight loss at the higher quartile was associated with improvements of adiponectin levels (p < 0.05).
  
  
  CONCLUSIONS
  Weight loss was associated with increased total and HMW adiponectin levels regardless of the diet type. Enhancing weight loss may be a means to improve adiponectin levels.
authors.affiliation: a School of Nursing.
authors.forename: Sushama D
authors.initials: SD
authors.lastname: Acharya
authors.forename: Maria M
authors.initials: MM
authors.lastname: Brooks
authors.forename: Rhobert W
authors.initials: RW
authors.lastname: Evans
authors.forename: Faina
authors.initials: F
authors.lastname: Linkov
authors.forename: Lora E
authors.initials: LE
authors.lastname: Burke
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D031204:Caloric Restriction; D015930:Diet Records; D018752:Diet, Fat-Restricted; D014676:Diet, Vegetarian; D002149:Energy Intake; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D015596:Nutrition Assessment; D009765:Obesity / Q000178:diet therapy*; D050177:Overweight / Q000178:diet therapy*; D010349:Patient Compliance; D015431:Weight Loss; D055815:Young Adult
chemical_list: D052242:Adiponectin