title: [Chordoma: diagnostic considerations and review of the literature].
abstract: Chordoma is a rare malignant tumor of the bone; it arises from embryonic remnants of the primitive notochord and occurs along the midline from the skull base to the sacrum. In this article, we reviewed the origin, location, clinical, histopatological and imaging features, treatment, and differential diagnosis of chordoma.
authors.forename: Renata
authors.initials: R
authors.lastname: Conforti
authors.forename: Angela
authors.initials: A
authors.lastname: Sardaro
authors.forename: Mario
authors.initials: M
authors.lastname: Tecame
authors.forename: Claudia
authors.initials: C
authors.lastname: Rossi
authors.forename: Ottavia
authors.initials: O
authors.lastname: Vargas
authors.forename: Antonio
authors.initials: A
authors.lastname: Raucci
authors.forename: Assunta
authors.initials: A
authors.lastname: Sica
mesh_terms: D014408:Biomarkers, Tumor; D002813:Chondrosarcoma / Q000175:diagnosis; D002817:Chordoma / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000196:embryology / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D003287:Contrast Media; D016371:Cranial Irradiation; D003399:Craniotomy; D003937:Diagnosis, Differential; D005870:Giant Cell Tumors / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009361:Neoplasm Invasiveness; D059906:Neuroimaging / Q000379:methods*; D009672:Notochord / Q000473:pathology; D010014:Osteolysis / Q000209:etiology / Q000473:pathology; D010954:Plasmacytoma / Q000175:diagnosis; D019292:Skull Base Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000196:embryology / Q000473:pathology / Q000628:therapy; D013117:Spinal Cord Compression / Q000209:etiology / Q000473:pathology; D013125:Spinal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000196:embryology / Q000473:pathology / Q000628:therapy; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D014408:Biomarkers, Tumor; D003287:Contrast Media