title: Analysis of ultrasonic waves propagating in a bone plate over a water half-space with and without overlying soft tissue.
abstract: Recent in vitro studies have shown that guided waves can characterize bone properties. However, for clinical applications to be viable, the soft-tissue layer should be considered. This study examined the effect of soft tissue on guided waves using a bovine bone plate over a water half-space and overlaid by a 4-mm gelatin-based soft-tissue mimic. The data (with and without soft tissue) clearly show a high-frequency, fast-propagating wave packet and a low-frequency, delayed phase group. The presence of soft tissue attenuates the signals significantly and increases mode density and number as predicted by theory. The data retain higher frequency content than the bone-plate data at large offsets. Using theoretical dispersion curves, the guided modes can be identified with mode 1 (similar to the A0 Lamb mode) minimally affected by the addition of soft tissue. There is infiltration of high-frequency, late-arriving energy within the low-velocity guided-wave regime. Results of travel-time calculation suggest that P-wave and PP-reflections/multiples within the soft tissue may be responsible for the high-frequency oscillations.
authors.affiliation: Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Tho N H T
authors.initials: TN
authors.lastname: Tran
authors.forename: Lauren
authors.initials: L
authors.lastname: Stieglitz
authors.forename: Yu J
authors.initials: YJ
authors.lastname: Gu
authors.forename: Lawrence H
authors.initials: LH
authors.lastname: Le
mesh_terms: D000818:Animals; D001834:Body Water / Q000502:physiology* / Q000528:radiation effects; D001842:Bone and Bones / Q000502:physiology* / Q000528:radiation effects; D003198:Computer Simulation; D003238:Connective Tissue / Q000502:physiology* / Q000528:radiation effects; D019220:High-Energy Shock Waves; D006801:Humans; D008954:Models, Biological; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods*; D012542:Scattering, Radiation
keywords: Attenuation; Axial transmission; Cortical bone; Dispersion; Guided waves; Osteoporosis; Soft tissue; Ultrasound