title: A redox-responsive cationic supramolecular polymer constructed from small molecules as a promising gene vector.
abstract: A novel class of redox-responsive cationic supramolecular polymer with effective DNA condensation ability and H2O2-induced DNA release behavior has been successfully constructed from small molecules. This supramolecular polymer can be used in vitro as a promising nonviral vector for gene therapy.
authors.affiliation: School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, 800 Dongchuan Road, 200240 Shanghai, People's Republic of China. yuesu@sjtu.edu.cn xyzhu@sjtu.edu.cn.
authors.forename: Ruijiao
authors.initials: R
authors.lastname: Dong
authors.forename: Yue
authors.initials: Y
authors.lastname: Su
authors.forename: Songrui
authors.initials: S
authors.lastname: Yu
authors.forename: Yongfeng
authors.initials: Y
authors.lastname: Zhou
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Lu
authors.forename: Xinyuan
authors.initials: X
authors.lastname: Zhu
mesh_terms: D002412:Cations / Q000737:chemistry; D004247:DNA / Q000737:chemistry; D019281:Dimerization; D005296:Ferrous Compounds / Q000737:chemistry*; D015316:Genetic Therapy; D005822:Genetic Vectors / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry; D046911:Macromolecular Substances / Q000737:chemistry; D000075163:Metallocenes; D010084:Oxidation-Reduction; D010957:Plasmids / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D002412:Cations; D005296:Ferrous Compounds; D046911:Macromolecular Substances; D000075163:Metallocenes; D011108:Polymers; D047392:beta-Cyclodextrins; D004247:DNA; D006861:Hydrogen Peroxide; C031215:betadex; C004998:ferrocene