title: [Usefulness of thoracoscopy under local anesthesia in the diagnosis of tuberculous pleurisy occurring during infliximab administration: a case report].
abstract: We report the case of a 71-year-old man with rheumatoid arthritis. Infliximab administration was started as treatment for rheumatoid arthritis in January 2009. As he showed a positive result for the tuberculin test, he was treated with isoniazid for 9 months. He was subsequently referred to our department in October 2011 with a right-sided pleural effusion. When thoracoscopy was performed under local anesthesia, white and red protruding lesions of various sizes were observed in the pleural cavity. A biopsy revealed fibrous granulation tissue, and tissue culture and all sensitivity tests were positive for Mycobacterium tuberculosis. Therefore, thoracoscopy is useful for not only diagnosis but also determining whether resistant tuberculosis is present.
authors.affiliation: Division of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan. satishii@hosp.ncgm.go.jp
authors.forename: Satoru
authors.initials: S
authors.lastname: Ishii
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Takeda
authors.forename: Jin
authors.initials: J
authors.lastname: Takasaki
authors.forename: Masayuki
authors.initials: M
authors.lastname: Hojo
authors.forename: Haruhito
authors.initials: H
authors.lastname: Sugiyama
mesh_terms: D000368:Aged; D000772:Anesthesia, Local; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D006801:Humans; D000069285:Infliximab; D008297:Male; D013906:Thoracoscopy / Q000379:methods*; D014396:Tuberculosis, Pleural / Q000175:diagnosis* / Q000473:pathology
chemical_list: D000911:Antibodies, Monoclonal; D000069285:Infliximab