title: Clinical practice guidelines for the treatment of invasive Aspergillus infections in adults in the Middle East region: Expert panel recommendations.
abstract: The incidence of invasive Aspergillus infections in the Middle East continues to rise with the increase in the number of immunocompromised patients, and carries significant morbidity and mortality. A panel of experts analysed the evidence from the most recent international guidelines and relevant published literature to reach consensus and develop clear clinical practice guidelines to aid diagnosis and treatment of invasive Aspergillus infections in the Middle East. Disease-specific recommendations were provided for the management of invasive aspergillosis. The expert panel acknowledged that these guidelines should be followed as closely as possible but used alongside clinical judgement.
authors.affiliation: King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. Electronic address: habdely@gmail.com.
authors.forename: Hail M
authors.initials: HM
authors.lastname: Al-Abdely
authors.affiliation: King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia. Electronic address: othmanaf@hotmail.com.
authors.forename: Adel F
authors.initials: AF
authors.lastname: Alothman
authors.affiliation: Arabian Gulf University, Ministry of Health, Bahrain. Electronic address: jalsalman@hotmail.com.
authors.forename: Jameela Al
authors.initials: JA
authors.lastname: Salman
authors.affiliation: Saad Specialist Hospital, Al-Khobar, Saudi Arabia. Electronic address: dr_tmusawi@hotmail.com.
authors.forename: Tariq
authors.initials: T
authors.lastname: Al-Musawi
authors.affiliation: Hamad Medical Corporation (HMC), Weill Cornell Medical College, Qatar. Electronic address: malmaslamani@hmc.org.qa.
authors.forename: Muna
authors.initials: M
authors.lastname: Almaslamani
authors.affiliation: Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates. Electronic address: aabutt@skmc.ae.
authors.forename: Adeel A
authors.initials: AA
authors.lastname: Butt
authors.affiliation: King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia. Electronic address: thaqafiao1@ngha.med.sa.
authors.forename: Abdulhakeem O
authors.initials: AO
authors.lastname: Al Thaqafi
authors.affiliation: Pfizer Inc., Dubai, United Arab Emirates. Electronic address: nirvana.raghubir@pfizer.com.
authors.forename: Nirvana
authors.initials: N
authors.lastname: Raghubir
authors.affiliation: Pfizer Inc., Dubai, United Arab Emirates. Electronic address: waleed.elmorsi@pfizer.com.
authors.forename: Waleed El
authors.initials: WE
authors.lastname: Morsi
authors.affiliation: Lebanese University, Faculty of Medical Sciences, Beirut, Lebanon. Electronic address: nay04@mail.aub.edu.
authors.forename: Nadine A
authors.initials: NA
authors.lastname: Yared
mesh_terms: D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D008877:Middle East / Q000453:epidemiology; D017410:Practice Guidelines as Topic
keywords: ABCD; ABLC; ABPA; AMB colloidal dispersion; AMB lipid complex; AMB-D; Aspergillosis; Aspergillus; CNPA; CNS; ECIL4; European Council on Infections in Leukaemia; GVHD; Guidelines; HEPA; IA; IDSA; Infectious Disease Society of America; L-AMB; LFAB; Middle East; Treatment; allergic bronchopulmonary aspergillosis; amphotericin B deoxycholate; central nervous system; chronic necrotising pulmonary aspergillosis; graft-versus-host disease; high-efficiency particulate air filtration; invasive aspergillosis; lipid formulations of amphotericin B; liposomal amphotericin B