title: Sinus Augmentation With Platelet-Rich Fibrin in Combination With Bovine Bone Graft Versus Bovine Bone Graft in Combination With Collagen Membrane.
abstract: The purpose of this study was to compare the efficacy between the use of bovine bone graft material and platelet-rich fibrin (PRF) mixture (test group) and bovine bone graft material and collagen membrane combination (control group) in 2-stage maxillary sinus augmentation. According to specific inclusion/exclusion criteria, patients treated between 2008 and 2012 were selected. Panoramic radiographs were used for radiologic assessments. To evaluate the relationship between sinus-graft height and each implant, the bone level (BL) was divided by implant length (IL). To evaluate the change in the height of grafted sinus, the grafted sinus floor above the lowest part of the original sinus height (GSH) was divided by the original sinus height (OSH). Samples taken during implant surgery were used for histologic and histomorphometric analyses. Twenty-five patients, 32 augmentation surgeries, and 66 one-stage implants were included in the study. No implant loss or complication was observed in either group. There were no statistical differences according to new bone formation (P = .61) and biomaterial remnant (P = .87). During the evaluation period, the test group showed statistically less change in the BL/IL ratio (P = .022). The difference of GSH/OSH ratio was found to be insignificant between groups (P = .093). It was observed that the grafted sinus covering the implant apex and sinus floor was above the original sinus height in both groups. It may be concluded from this study that both combinations can be successfully used for sinus augmentation. Further studies evaluating different graft materials and PRF combinations in the early phases of healing would be beneficial.
authors.affiliation: 1  Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
authors.forename: Nilufer
authors.initials: N
authors.lastname: Bolukbasi
authors.affiliation: 1  Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
authors.forename: Selim
authors.initials: S
authors.lastname: Ersanlı
authors.affiliation: 2  Department of Histology and Embryology, Istanbul University, Istanbul, Turkey.
authors.forename: Nurullah
authors.initials: N
authors.lastname: Keklikoglu
authors.affiliation: 1  Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
authors.forename: Cansu
authors.initials: C
authors.lastname: Basegmez
authors.affiliation: 1  Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
authors.forename: Tayfun
authors.initials: T
authors.lastname: Ozdemir
mesh_terms: D000818:Animals; D018786:Bone Substitutes; D016025:Bone Transplantation; D002417:Cattle; D003094:Collagen; D003758:Dental Implantation, Endosseous; D006801:Humans; D008443:Maxillary Sinus; D000073183:Platelet-Rich Fibrin; D059546:Sinus Floor Augmentation
chemical_list: D018786:Bone Substitutes; D003094:Collagen
keywords: bovine bone graft; collagen membrane; platelet-rich fibrin; sinus augmentation