title: [Different significance in normal subjects and in glaucoma patients tested with Optopol PTS-910, in the galucoma program].
abstract: OBJECTIVE
  to quantify the inter-test variability (dB) for the Optopol PTS automated perimeter, Glaucoma Fast threshold program.
  
  
  METHODS
  A prospective study was performed on 166 glaucomatous patients and a control group of 30 normal subjects, tested by complete ophthalmological exam and automated perimetry (Optopol PTS-910). The visual field was tested weekly for 4 consecutive weeks. The visual field defects were classified according to the Aulhorn-Karmeyer descriptive scale.
  
  
  RESULTS
  For the control group, the medium inter-test variability was of 1.57 +/- 0.24 dB, lower next to fixation and increasing towards the 50 degree isopter. The medium inter-test variability increases along with the perimetric stage :1.57 +/- 0.66 dB for pre-perimetric glaucoma, 2.13 + 1.04 dB for non-specific defects group, 3.23 + 1.01 dB for the stage 1, 3.52 + 2.61 dB, for the stage 2, 3.65 + 1.19dB for the stage 3 and 5.82 +/- 1.67dB for the stage 4. For the cases of preperimetric glaucoma and non-specific defects, a similar profile of variability to the normal subjects can be observed. For the stages 2-4, the profile of the areas with maxim inter-test variability moves towards the relative scotoma and the surrounding area.
  
  
  CONCLUSIONS
  A better description of the inter-test variability and the evolution of this intricate parameter of the retinal light sensitivity is useful for the differential diagnostic between the real change and the "background noise" in early detection of the functional progression in glaucoma.
authors.affiliation: Universitatea de Medicină şi Farmacie Carol Davila Bucureşti.
authors.forename: Ana Maria
authors.initials: AM
authors.lastname: Dascalu
authors.forename: Alina Popa
authors.initials: AP
authors.lastname: Cherecheanu
authors.forename: Daniela
authors.initials: D
authors.lastname: Stana
authors.forename: Dragoş
authors.initials: D
authors.lastname: Serban
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003937:Diagnosis, Differential; D018450:Disease Progression; D042241:Early Diagnosis; D005902:Glaucoma, Open-Angle / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D011237:Predictive Value of Tests; D011446:Prospective Studies; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D058609:Visual Field Tests / Q000295:instrumentation / Q000379:methods*