title: Clinical and radiologic results of endovascular coil embolization for cerebral aneurysm in young patients.
abstract: OBJECTIVE
  This study is an overview of the clinical and radiologic outcomes of endovascular coil embolization for cerebral aneurysm in patients aged 40 years and younger.
  
  
  METHODS
  Between January 2008 and June 2011, 218 aneurysms were treated using endovascular coil embolization and followed up with cerebral angiography at least six months later. Twenty-one aneurysms occurred in patients aged 40 years and younger, while 197 occurred in 179 patients older than 40 years. The clinical and radiologic results were retrospectively analyzed and compared between the two groups using the modified Rankin scale scores and the modified Raymond scale.
  
  
  RESULTS
  Follow-up cerebral angiography revealed two (9.5%) major and two (9.5%) minor recanalized aneurysms in patients aged 40 years and younger, and six (3.0%) major and 35 (17.7%) minor recanalized aneurysms in patients older than 40 years. However, the differences between the groups were not statistically significant. The preoperative and postoperative mean modified Rankin scale scores at time for follow-up angiography were 1.14 and 0.19 respectively for patients aged 40 years and younger, and 1.30 and 0.30 respectively for patients older than 40 years.
  
  
  CONCLUSIONS
  The younger patients had clinically favorable outcomes with tolerable angiographic follow-up results. More regular and long-term imaging follow-up is required for younger patients due to their longer life expectancy.
authors.affiliation: Department of Neurosurgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
authors.forename: Hyun Seok
authors.initials: HS
authors.lastname: Park
authors.forename: Soon Chan
authors.initials: SC
authors.lastname: Kwon
authors.forename: Shang Hoon
authors.initials: SH
authors.lastname: Shin
authors.forename: Eun Suk
authors.initials: ES
authors.lastname: Park
authors.forename: Hong Bo
authors.initials: HB
authors.lastname: Sim
authors.forename: In Uk
authors.initials: IU
authors.lastname: Lyo
keywords: Age groups; Cerebral aneurysm; Coil embolization; Treatment outcomes
references.citation: Childs Nerv Syst. 2001 Jan;17(1-2):37-41
references.pmid: 11219621
references.citation: Stroke. 2000 Jan;31(1):100-10
references.pmid: 10625723
references.citation: J Neurosurg. 1992 Oct;77(4):515-24
references.pmid: 1527608
references.citation: AJNR Am J Neuroradiol. 1994 May;15(5):815-20
references.pmid: 8059647
references.citation: Stroke. 2001 Sep;32(9):1998-2004
references.pmid: 11546888
references.citation: Neurosurgery. 1998 Nov;43(5):1016-25
references.pmid: 9802844
references.citation: Neurosurgery. 2007 Apr;60(4):626-36; discussion 636-7
references.pmid: 17415199
references.citation: Childs Nerv Syst. 1986;2(4):185-90
references.pmid: 3779680
references.citation: Br J Neurosurg. 1991;5(6):575-80
references.pmid: 1772602
references.citation: Neuroradiology. 2007 Jan;49(1):41-7
references.pmid: 17094000
references.citation: J Neurosurg. 1991 Jul;75(1):8-14
references.pmid: 2045924
references.citation: Stroke. 2002 Jan;33(1):210-7
references.pmid: 11779912
references.citation: Acta Neurochir (Wien). 1985;77(3-4):103-9
references.pmid: 4072780
references.citation: J Neurosurg. 1984 Jun;60(6):1163-6
references.pmid: 6726359
references.citation: Radiology. 1998 Feb;206(2):499-510
references.pmid: 9457205
references.citation: Neurosurgery. 2002 Feb;50(2):239-49; discussion 249-50
references.pmid: 11844258
references.citation: Radiology. 1997 Mar;202(3):783-92
references.pmid: 9051034
references.citation: Neurosurgery. 2006 Nov;59(5 Suppl 3):S93-102; discussion S3-13
references.pmid: 17053622
references.citation: Neurosurgery. 2006 Jan;58(1):51-9; discussion 51-9
references.pmid: 16385329
references.citation: Stroke. 2003 Jun;34(6):1398-403
references.pmid: 12775880
references.citation: Lancet. 2002 Oct 26;360(9342):1267-74
references.pmid: 12414200
references.citation: Radiology. 1999 Aug;212(2):348-56
references.pmid: 10429689
references.citation: Radiology. 2003 Jun;227(3):720-4
references.pmid: 12773678
references.citation: Acta Neurochir (Wien). 2001;143(5):451-5
references.pmid: 11482694
references.citation: Neurol Med Chir (Tokyo). 2004 Sep;44(9):456-65; discussion 466
references.pmid: 15600280
references.citation: J Neurosurg. 2003 May;98(5):959-66
references.pmid: 12744354