title: A Pt-nanoparticle electrocatalytic assay used for PCR-free sensitive telomerase detection.
abstract: An electrocatalytic assay was developed for telomerase activity detection by using superior catalytic properties of Pt nanoparticles. This design was PCR-free, and highly sensitive for telomerase with a detection limit of less than 2 cells.
authors.affiliation: Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. xqu@ciac.ac.cn.
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Zhang
authors.forename: Li
authors.initials: L
authors.lastname: Wu
authors.forename: Jiasi
authors.initials: J
authors.lastname: Wang
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D001681:Biological Assay / Q000379:methods*; D004563:Electrochemistry; D006801:Humans; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry*; D015394:Molecular Structure; D010984:Platinum / Q000737:chemistry*; D016133:Polymerase Chain Reaction; D019098:Telomerase / Q000032:analysis* / Q000737:chemistry
chemical_list: D010984:Platinum; D019098:Telomerase