title: Long noncoding RNAs usher in a new era in the biology of enhancers.
abstract: Enhancer-associated long noncoding RNAs act over long distances and across chromosomes to activate transcription at distal promoters. Here, we address the latest advances made toward understanding the role of long noncoding RNA expression and the involvement of these RNAs in enhancer function through association with protein factors and modulation of chromatin structure.
authors.affiliation: Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany. Electronic address: oerom@molgen.mpg.de.
authors.forename: Ulf Andersson
authors.initials: UA
authors.lastname: Ørom
authors.forename: Ramin
authors.initials: R
authors.lastname: Shiekhattar
mesh_terms: D000818:Animals; D002843:Chromatin / Q000378:metabolism; D004742:Enhancer Elements, Genetic; D006801:Humans; D011401:Promoter Regions, Genetic; D062085:RNA, Long Noncoding / Q000378:metabolism*; D014158:Transcription, Genetic; D015533:Transcriptional Activation
chemical_list: D002843:Chromatin; D062085:RNA, Long Noncoding
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