title: Precise patterning of silk microstructures using photolithography.
abstract: Photolithography is used in conjunction with a "silk fibroin photoresist" to form precise protein microstructures directly and rapidly on a variety of substrates. High-resolution features in two and three dimensions with line widths down to one micrometer are formed. Photo-crosslinked protein structures guide cell adhesion, providing precise spatial control of cells without requiring adhesive ligands.
authors.affiliation: Department of Chemical and Life Science Engineering, Virginia Commonwealth University, 601 W Main Street, Richmond, VA, USA, 23284.
authors.forename: Nicholas E
authors.initials: NE
authors.lastname: Kurland
authors.forename: Tuli
authors.initials: T
authors.lastname: Dey
authors.forename: Subhas C
authors.initials: SC
authors.lastname: Kundu
authors.forename: Vamsi K
authors.initials: VK
authors.lastname: Yadavalli
keywords: fibroin; micropatterning; photolithography; protein photoresist; silk