title: Characteristics of atheromatous renovascular disease in Dubai: a single-center experience.
abstract: To determine the characteristics of atherosclerotic renal artery stenosis (ARAS) in a cohort of patients who attended the Nephrology Department of NMC Specialty Hospital in Dubai from 2006 through 2010, including their clinical and investigational features and their response to various remedial modalities, we studied 20 patients with a diagnosis of ARAS based on magnetic resonance angiography. Three (15%) patients developed acute renal failure (ARF) after the initiation of angiotensin converting enzyme inhibitors or angiotensin II receptor blockers and 13 (65%) patients presented with chronic kidney disease (CKD) of either ischemic nephropathy or nephroangiosclerosis etiology. Four (20%) patients presented with resistant arterial hypertension (RAH). Plasma renin activity was elevated in all the patients. Fifteen (75%) patients were diabetics. We conclude that CKD was the main presentation of ARAS followed by RAH and ARF in our study. Diabetes Mellitus was the main risk factor for ARAS found in our study.
authors.affiliation: NMC Specialty Hospital, Dubai, United Arab Emirates. drwaellatif@hotmail.com
authors.forename: Wael Lateef
authors.initials: WL
authors.lastname: Jebur
authors.forename: Khalid
authors.initials: K
authors.lastname: Abdulla
authors.forename: Sohrab
authors.initials: S
authors.lastname: Tomaraei
mesh_terms: D000368:Aged; D003404:Creatinine / Q000097:blood; D003928:Diabetic Nephropathies / Q000150:complications / Q000473:pathology; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D058226:Plaque, Atherosclerotic / Q000150:complications / Q000473:pathology*; D012078:Renal Artery Obstruction / Q000150:complications / Q000473:pathology*; D051436:Renal Insufficiency, Chronic / Q000150:complications; D012083:Renin / Q000097:blood; D012307:Risk Factors; D014479:United Arab Emirates
chemical_list: D003404:Creatinine; D012083:Renin