title: Mixed cryoglobulinemia and thyroid autoimmune disorders.
abstract: In patients with hepatitis C virus-associated mixed cryoglobulinemia (MC+HCV) the following thyroid disorders are significantly more frequent than in HCV not infected controls: 1) high levels of serum anti-thyroperoxidase autoantibody (AbTPO), 2) high levels of serum AbTPO and/or anti-thyroglobulin (AbTg) autoantibody; 3) humoral and ultrasonographical signs of thyroid autoimmunity (35%); 4) prevalence of subclinical hypothyroidism (11%). Also, the prevalence of papillary thyroid cancer has been found higher in MC+HCV patients than in controls, in particular in patients with autoimmune thyroiditis. These results suggest a careful monitoring of thyroid function in these patients.
authors.affiliation: Departments of Clinical and Experimental Medicine, University of Pisa, Pisa.
authors.forename: P
authors.initials: P
authors.lastname: Fallahi
authors.forename: S M
authors.initials: SM
authors.lastname: Ferrari
authors.forename: D
authors.initials: D
authors.lastname: Giuggioli
authors.forename: A
authors.initials: A
authors.lastname: Corrado
authors.forename: S
authors.initials: S
authors.lastname: Fabiani
authors.forename: S
authors.initials: S
authors.lastname: Marchi
authors.forename: C
authors.initials: C
authors.lastname: Ferri
authors.forename: A
authors.initials: A
authors.lastname: Antonelli
mesh_terms: D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications*; D003449:Cryoglobulinemia / Q000150:complications*; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D013959:Thyroid Diseases / Q000150:complications* / Q000276:immunology*