title: Hepatic pseudocystic metastasis of well-differentiated ileal neuroendocrine tumor: a case report with review of the literature.
abstract: Imaging appearance of cyst-like changes is most frequently described in primary neuroendocrine lesions, especially pancreatic NETs.The imaging finding of a pseudocystic lesion of the liver puts in differential diagnosis many pathologies such as infectious diseases, simple biliary cysts up to biliary cystadenomas and eventually to primary or metastatic malignancies.Primary or metastatic hepatic malignancies with pseudocystic aspects are rare, and a pseudocystic aspect is reported only after neo-adjuvant treatment.Liver metastasis of untreated neuroendocrine tumors are usually solid and, to our knowledge, only two cases of neuroendocrine cystic hepatic metastases of ileal atypical carcinoids have been reported so far.We present a case of a 67 years old man with synchronous finding of an untreated hepatic pseudocystic lesion and an ileal mass histologically diagnosed as a well differentiated (G1) neuroendocrine tumor.
  The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1443883503102967.
authors.affiliation: Division of Pathology, Fondazione IRCCS "Ca' Granda" - Ospedale Maggiore Policlinico, Via Francesco Sforza 35, Milano 20100, Italy. alessandro.delgobbo@unimi.it.
authors.forename: Stefano
authors.initials: S
authors.lastname: Fiori
authors.forename: Alessandro
authors.initials: A
authors.lastname: Del Gobbo
authors.forename: Gabriella
authors.initials: G
authors.lastname: Gaudioso
authors.forename: Lucio
authors.initials: L
authors.lastname: Caccamo
authors.forename: Sara
authors.initials: S
authors.lastname: Massironi
authors.forename: Federica
authors.initials: F
authors.lastname: Cavalcoli
authors.forename: Silvano
authors.initials: S
authors.lastname: Bosari
authors.forename: Stefano
authors.initials: S
authors.lastname: Ferrero
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D002454:Cell Differentiation; D017024:Chemotherapy, Adjuvant; D003082:Colectomy; D003560:Cysts / Q000473:pathology*; D003937:Diagnosis, Differential; D006498:Hepatectomy; D006801:Humans; D007078:Ileal Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000737:chemistry / Q000556:secondary* / Q000628:therapy; D008297:Male; D018297:Neoplasms, Cystic, Mucinous, and Serous / Q000737:chemistry / Q000556:secondary* / Q000628:therapy; D018358:Neuroendocrine Tumors / Q000737:chemistry / Q000556:secondary* / Q000628:therapy; D011237:Predictive Value of Tests; D013004:Somatostatin / Q000031:analogs & derivatives / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D013004:Somatostatin
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