title: Diphenylcyclopropenone-induced vitiligo in a patient with alopecia universalis.
abstract: Alopecia areata and vitiligo are autoimmune diseases, both associated with multiple autoimmune comorbidities. Many studies show colocalization of these diseases at the same anatomical site. Here, we have a case where both disorders were reported to present in the same patient. Diphenylcyclopropenone (diphencyprone, DCP) is used in the treatment of alopecia areata and may induce vitiligo in some patients. We report on one case of vitiligo that was induced by DCP during therapy for alopecia universalis. Alopecia areata and vitiligo share many susceptibility genes. Follicular melanocyte destruction may represent the link between the two diseases.
authors.affiliation: Dermatology Department, Rumailah Hospital, Doha, Qatar.
authors.forename: Hassan
authors.initials: H
authors.lastname: Riad
authors.forename: Haya Al
authors.initials: HA
authors.lastname: Mannai
authors.forename: Khalid
authors.initials: K
authors.lastname: Mansour
authors.forename: Khalifa Al
authors.initials: KA
authors.lastname: Qaatri
authors.forename: Sharifa Al
authors.initials: SA
authors.lastname: Dosari
authors.forename: Amina Al
authors.initials: AA
authors.lastname: Obaidaly
authors.forename: Emad
authors.initials: E
authors.lastname: Sultan
keywords: Alopecia; Diphenylcyclopropenone; Vitiligo
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