title: Novel pharmacological agents targeting memory and cognition in the treatment of anxiety disorders.
abstract: OBJECTIVE
  The aim of this study is to review data for several promising novel pharmacological drugs for anxiety disorders and describe how they exert their effects.
  
  
  METHODS
  We presented a review of the published literature. Online search plus reference list checking was also used.
  
  
  RESULTS
  The neurobiology of anxiety is overviewed. N-methyl-D-aspartate and beta adrenaline are involved in memory consolidation. We describe studies using memantine, D-cycloserine, propranolol, and riluzole that modulate these pathways.
  
  
  CONCLUSIONS
  There are a number of promising new therapies, but these require further studies before they can enter routine clinical practice.
authors.forename: Harpal Singh
authors.initials: HS
authors.lastname: Nandhra
authors.forename: Catherine Louise
authors.initials: CL
authors.lastname: Murphy
authors.forename: Akeem
authors.initials: A
authors.lastname: Sule
mesh_terms: D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001008:Anxiety Disorders / Q000188:drug therapy* / Q000503:physiopathology; D003071:Cognition / Q000187:drug effects; D015195:Drug Design; D006801:Humans; D008568:Memory / Q000187:drug effects; D058990:Molecular Targeted Therapy; D016202:N-Methylaspartate / Q000378:metabolism; D011943:Receptors, Adrenergic, beta / Q000378:metabolism
chemical_list: D014151:Anti-Anxiety Agents; D011943:Receptors, Adrenergic, beta; D016202:N-Methylaspartate