title: Metallo-toeholds: controlling DNA strand displacement driven by Hg(II) ions.
abstract: Toehold-mediated strand displacement is a powerful tool that permits programmable control over DNA hybridization. Here, we developed a mechanism for strand displacement driven by Hg(2+) ions, in which the insertion of thymine-thymine mismatched base pairs on the toeholds provides additional control through variation of the concentration of Hg(2+) ions.
authors.affiliation: CAS Key Laboratory of Soft Matter Chemistry, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China. hjliang@ustc.edu.cn.
authors.forename: Wei
authors.initials: W
authors.lastname: Ding
authors.forename: Wei
authors.initials: W
authors.lastname: Deng
authors.forename: Hong
authors.initials: H
authors.lastname: Zhu
authors.forename: Haojun
authors.initials: H
authors.lastname: Liang
mesh_terms: D020137:Base Pair Mismatch; D004247:DNA / Q000187:drug effects* / Q000235:genetics; D004587:Electrophoresis, Agar Gel; D008627:Mercuric Chloride / Q000737:chemistry* / Q000494:pharmacology; D013941:Thymine / Q000737:chemistry
chemical_list: D008627:Mercuric Chloride; D004247:DNA; D013941:Thymine