title: Theoretical Investigation of Optical Detection and Recognition of Single Biological Molecules Using Coherent Dynamics of Exciton-Plasmon Coupling.
abstract: We use quantum coherence in a system consisting of one metallic nanorod and one semi-conductor quantum dot to investigate a plasmonic nanosensor capable of digital optical detection and recognition of single biological molecules. In such a sensor the adsorption of a specific molecule to the nanorod turns off the emission of the system when it interacts with an optical pulse having a certain intensity and temporal width. The proposed quantum sensors can count the number of molecules of the same type or differentiate between molecule types with digital optical signals that can be measured with high certainty. We show that these sensors are based on the ultrafast upheaval of coherent dynamics of the system and the removal of coherent blockage of energy transfer from the quantum dot to the nanorod once the adsorption process has occurred.
authors.affiliation: Department of Physics, University of Alabama in Huntsville, Huntsville, Alabama, 35899, USA.
authors.forename: S M
authors.initials: SM
authors.lastname: Sadeghi
authors.forename: B
authors.initials: B
authors.lastname: Hood
authors.forename: K D
authors.initials: KD
authors.lastname: Patty
authors.forename: C-B
authors.initials: CB
authors.lastname: Mao
keywords: Quantum dots; dynamics; metallic; nanorods; nanosensors; quantum coherence
references.citation: Opt Lett. 2007 Aug 1;32(15):2125-7
references.pmid: 17671558
references.citation: Nanotechnology. 2012 Feb 17;23(6):065701
references.pmid: 22248503
references.citation: Nat Nanotechnol. 2012 Apr 15;7(6):379-82
references.pmid: 22504707
references.citation: Nano Lett. 2008 Oct;8(10):3450-5
references.pmid: 18767880
references.citation: Nanotechnology. 2010 Jun 25;21(25):255503
references.pmid: 20516579
references.citation: Nano Lett. 2008 Jul;8(7):2106-11
references.pmid: 18558787
references.citation: Plasmonics. 2006 Mar 1;1(1):5-33
references.pmid: 19890454
references.citation: J Phys Condens Matter. 2013 Jan 30;25(4):045304
references.pmid: 23257986
references.citation: Nanotechnology. 2013 Jan 11;24(1):015502
references.pmid: 23220909
references.citation: Phys Rev Lett. 2003 Feb 21;90(7):077403
references.pmid: 12633271
references.citation: Phys Rev Lett. 2004 Oct 15;93(16):166108
references.pmid: 15525013
references.citation: Nat Biotechnol. 2005 Jun;23(6):741-5
references.pmid: 15908940
references.citation: Nanotechnology. 2009 Jan 7;20(1):015305
references.pmid: 19417250
references.citation: J Am Chem Soc. 2002 Sep 4;124(35):10596-604
references.pmid: 12197762
references.citation: Nano Lett. 2007 Apr;7(4):1054-8
references.pmid: 17378619
references.citation: Nano Lett. 2011 Apr 13;11(4):1826-30
references.pmid: 21428275