title: Templated hierarchical self-assembly of poly(p-aryltriazole) foldamers.
abstract: A biomimetic approach has been used for the templated self-assembly of a helical poly(para-aryltriazole) foldamer. The solvophobic folding process yields helices that further self-assemble into long nanotubes (see picture; scale bar: 100 nm). Constructs of controlled length and chirality can be generated by applying a poly(γ-benzyl-l-glutamate) scaffold at the appropriate assembly conditions, mimicking tobacco mosaic virus self-assembly.
authors.affiliation: Stellenbosch University, Department of Chemistry and Polymer Science, Private Bag X1, Matieland 7602 (South Africa) http://www.klumperman-group.net/
authors.forename: Rueben
authors.initials: R
authors.lastname: Pfukwa
authors.forename: Paul H J
authors.initials: PH
authors.lastname: Kouwer
authors.forename: Alan E
authors.initials: AE
authors.lastname: Rowan
authors.forename: Bert
authors.initials: B
authors.lastname: Klumperman
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D008968:Molecular Conformation; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D017433:Protein Structure, Secondary; D013698:Templates, Genetic; D014230:Triazoles / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D011108:Polymers; D014230:Triazoles
keywords: biomimetic synthesis; foldamers; information transfer; self-assembly; template