title: Early features in acute macular neuroretinopathy.
abstract: Acute macular neuroretinopathy (AMNR) is a rare disorder characterised by acute onset of unilateral or bilateral visual impairment associated with reddish-brown wedge-shaped outer macular lesions. It is more frequently reported in young females and though the pathophysiology remains unclear, factors reported in association with its onset include post-viral illness and vasoconstrictor use. We report a case of AMNR in an 18-year old female patient presenting with a 2-day history of acute painless blurring of central vision bilaterally, following 1 month of preceding flu-like illness. For 1 week prior to presentation, the patient had taken large doses of oral preparations containing phenylephrine hydrochloride. In addition to demonstrating characteristic optical coherence tomography findings seen in AMNR, we illustrate some rarely seen acute ophthalmoscopic features. Based on associations from this case, we add further insight into the pathophysiology of this condition which remains poorly understood.
authors.affiliation: Department of Ophthalmology, King's College Hospital, Bessemer Road, London, SE5 9RS, UK.
authors.forename: Anurag
authors.initials: A
authors.lastname: Garg
authors.forename: Anish N
authors.initials: AN
authors.lastname: Shah
authors.forename: Theresa
authors.initials: T
authors.lastname: Richardson
authors.forename: Eoin
authors.initials: E
authors.lastname: O'Sullivan
authors.forename: Haralabos
authors.initials: H
authors.lastname: Eleftheriadis
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D012166:Retinal Hemorrhage / Q000473:pathology*; D014786:Vision Disorders / Q000175:diagnosis*
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