title: Photoacoustic Imaging for Cancer Detection and Staging.
abstract: Cancer is one of the leading causes of death in the world. Diagnosing a cancer at its early stages of development can decrease the mortality rate significantly and reduce healthcare costs. Over the past two decades, photoacoustic imaging has seen steady growth and has demonstrated notable capabilities to detect cancerous cells and stage cancer. Furthermore, photoacoustic imaging combined with ultrasound imaging and augmented with molecular targeted contrast agents is capable of imaging cancer at the cellular and molecular level, thus opening diverse opportunities to improve diagnosis of tumors, detect circulating tumor cells and identify metastatic lymph nodes. In this paper we introduce the principles of photoacoustic imaging, and review recent developments in photoacoustic imagingas an emerging imaging modality for cancer diagnosis and staging.
authors.affiliation: Department of Biomedical Engineering, University of Texas at Austin, Austin TX 78712, USA ; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota 55901, USA.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Mehrmohammadi
authors.forename: Soon Joon
authors.initials: SJ
authors.lastname: Yoon
authors.forename: Douglas
authors.initials: D
authors.lastname: Yeager
authors.forename: Stanislav Y
authors.initials: SY
authors.lastname: Emelianov
keywords: Photoacoustic imaging; cancer; diagnosis; exogenous contrast agents; spectroscopy; staging; ultrasound
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