title: The correlation study on antimicrobial resistance and biofilm related genes in clinical isolates of Acinetobacter baumannii.
abstract: In recent years, the proportion of nosocomial infections caused by Acinetobacter baumannii (Ab) strains has increased significantly, and its resistance to antibiotics is rising. The resistance mechanisms of Ab are complex, which include the integron formation, inactivating or deactivating enzyme, outer membrane permeability, biofilm formation, drug exocytosis mechanism and so on. The biofilm formation by bacteria leads to high resistance and immune evasion ability. The aim of this study is to investigate the resistance and distribution patterns of Ab isolates, and the biofilm formation related genes in Ab isolates in our hospital.
authors.affiliation: Department of Intensive Care Unit, the Affiliated Qingdao Municipal Hospital Dong Yuan of Qingdao University Medical College, Qingdao 266071, Shandong, China.
authors.forename: Rong
authors.initials: R
authors.lastname: Dong
authors.forename: Chun
authors.initials: C
authors.lastname: Guan
authors.forename: Dan
authors.initials: D
authors.lastname: Hu
authors.forename: Ting-ting
authors.initials: TT
authors.lastname: Xin
authors.forename: Yan
authors.initials: Y
authors.lastname: Qu
mesh_terms: D000151:Acinetobacter Infections / Q000382:microbiology*; D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D000890:Anti-Infective Agents / Q000494:pharmacology; D018441:Biofilms; D024881:Drug Resistance, Bacterial; D006801:Humans; D007362:Intensive Care Units; D008826:Microbial Sensitivity Tests
chemical_list: D000890:Anti-Infective Agents