title: [Expert consensus on the detection and clinical management of familial hypercholesterolemia].
abstract: Familial hypercholesterolemia (FH) is one of the most common and severe genetic diseases, causing disabilities and premature death to those who suffer it. Lipid-lowering therapy substantially improves the prognosis of FH patients and, therefore, appropriate pharmacological treatment is of the utmost importance. The Spanish Society of Arteriosclerosis (SEA) has always been a pioneer in the diagnosis and treatment of FH. Since its inception, FH has been one of the main areas of clinical and scientific interest, mainly for Lipids Units of the SEA, where most patients with this pathology are referred in Spain. This document arises from the willingness of our society to update the scientific knowledge on this subject and to provide physicians with clear clinical guidelines regarding diagnosis and treatment of FH. These guidelines can be summarized in two main aspects: early diagnosis of the disease and a rapid normalization of LDLcholesterol. In the coming years, health providers should accomplish that the majority of patients with FH are aware of their diagnosis and that adequate treatment is provided.
authors.affiliation: Sociedad Española de Arteriosclerosis, España.
authors.forename: Lluís
authors.initials: L
authors.lastname: Masana
authors.forename: Fernando
authors.initials: F
authors.lastname: Civeira
authors.forename: Juan
authors.initials: J
authors.lastname: Pedro-Botet
authors.forename: Isabel
authors.initials: I
authors.lastname: de Castro
authors.forename: Miguel
authors.initials: M
authors.lastname: Pocoví
authors.forename: Núria
authors.initials: N
authors.lastname: Plana
authors.forename: Rocío
authors.initials: R
authors.lastname: Mateo-Gallego
authors.forename: Estíbaliz
authors.initials: E
authors.lastname: Jarauta
authors.forename: Àngels
authors.initials: À
authors.lastname: Pedragosa
mesh_terms: D008078:Cholesterol, LDL / Q000097:blood; D042241:Early Diagnosis; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D017410:Practice Guidelines as Topic; D011379:Prognosis; D012955:Societies, Medical; D013030:Spain
chemical_list: D008078:Cholesterol, LDL; D000960:Hypolipidemic Agents
keywords: Clinical management; Directrices; Familial hypercholesterolemia; Guidelines; Hipercolesterolemia familiar; Manejo clínico