title: Factors associated with remission of eczema in children: a population-based follow-up study.
abstract: The aim of this study was to analyse factors associated with remission of atopic dermatitis (AD) in childhood. A population-based AD cohort of 894 children aged 1-3 years from a cross-sectional baseline study in 2000 was followed up in 2005. The association between remission, background, health, lifestyle, and environmental variables was estimated with crude and multivariable logistic regression. At follow-up, 52% of the children had remission. Independent factors at baseline predicting remission were: milder eczema (adjusted odds ratio (aOR), 1.43; 95% confidence interval (95% CI) 1.16-1.77); later onset of eczema (aOR 1.40; 95% CI 1.08-1.80); non-flexural eczema (aOR 2.57; 95% CI 1.62-4.09); no food allergy (aOR 1.51; 95% CI 1.11-2.04), and rural living (aOR 1.48; 95% CI 1.07-2.05). Certain aspects of AD and rural living were important for remission, but despite the initial hypotheses to the contrary, the environmental factors examined in this paper were not substantial predictors of remission.
authors.affiliation: Department of Dermatology, Skåne University Hospital, Lund University, SE-205 02 Malmö, Sweden. laura.von_kobyletzki@med.lu.se, Laura.vonKobyletzki@liv.se.
authors.forename: Laura B
authors.initials: LB
authors.lastname: von Kobyletzki
authors.forename: Carl-Gustaf
authors.initials: CG
authors.lastname: Bornehag
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Breeze
authors.forename: Malin
authors.initials: M
authors.lastname: Larsson
authors.forename: Cecilia Boman
authors.initials: CB
authors.lastname: Lindström
authors.forename: Åke
authors.initials: Å
authors.lastname: Svensson
mesh_terms: D017668:Age of Onset; D002675:Child, Preschool; D015331:Cohort Studies; D003876:Dermatitis, Atopic / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D012008:Recurrence; D012424:Rural Population / Q000706:statistics & numerical data; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013548:Sweden / Q000453:epidemiology