title: Improving cardiac myocytes performance by carbon nanotubes platforms.
abstract: The application of nanotechnology to the cardiovascular system has increasingly caught scientists' attention as a potentially powerful tool for the development of new generation devices able to interface, repair, or boost the performance of cardiac tissue. Carbon nanotubes (CNTs) are considered as promising materials for nanomedicine applications in general and have been recently tested toward excitable cell growth. CNTs are cylindrically shaped structures made up of rolled-up graphene sheets, with unique electrical, thermal, and mechanical properties, able to effectively conducting electrical current in electrochemical interfaces. CNTs-based scaffolds have been recently found to support the in vitro growth of cardiac cells: in particular, their ability to improve cardiomyocytes proliferation, maturation, and electrical behavior are making CNTs extremely attractive for the development and exploitation of interfaces able to impact on cardiac cells physiology and function.
authors.affiliation: Molecular Medicine Group, International Centre for Genetic Engineering and Biotechnology Trieste, Italy.
authors.forename: Valentina
authors.initials: V
authors.lastname: Martinelli
authors.forename: Giada
authors.initials: G
authors.lastname: Cellot
authors.forename: Alessandra
authors.initials: A
authors.lastname: Fabbro
authors.forename: Susanna
authors.initials: S
authors.lastname: Bosi
authors.forename: Luisa
authors.initials: L
authors.lastname: Mestroni
authors.forename: Laura
authors.initials: L
authors.lastname: Ballerini
keywords: cardiac tissue engineering; cardiomyocyte maturation; cardiomyocyte proliferation; nanotechnology; synthetic interface
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