title: Endothelial dysfunction in primary Sjögren syndrome.
abstract: OBJECTIVE
  In this study, we aimed to investigate endothelial functions in primary Sjögren syndrome.
  
  
  METHODS
  Thirty-five patients with primary Sjögren syndrome and 20 age and sex-matched healthy volunteers were recruited to the present study. Flow mediated dilatation of brachial artery and carotid intima-media thickness were measured in the study population.
  
  
  RESULTS
  Carotid intima-media thickness values were similar between groups (0.50 +/- 0.10, 0.53 +/- 0.08, p > 0.05). Flow mediated dilatation of the brachial artery was disrupted in the primary Sjögren syndrome group (7% vs 12%, p = 0.002).
  
  
  CONCLUSIONS
  There is endothelial dysfunction in patients with primary Sjögren syndrome, although they had comparable carotid intima-media thickness with the healthy control group.
authors.affiliation: Etlik Ihtisas Education and Research Hospital, Department of Cardiology, Ankara, Turkey. akyelahmet@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Akyel
authors.forename: Y
authors.initials: Y
authors.lastname: Tavil
authors.forename: C
authors.initials: C
authors.lastname: Yayla
authors.forename: A
authors.initials: A
authors.lastname: Tufan
authors.forename: A
authors.initials: A
authors.lastname: Kaya
authors.forename: M E
authors.initials: ME
authors.lastname: Tezcan
authors.forename: M A
authors.initials: MA
authors.lastname: Ozturk
authors.forename: B
authors.initials: B
authors.lastname: Boyaci
mesh_terms: D000328:Adult; D001916:Brachial Artery / Q000503:physiopathology*; D059168:Carotid Intima-Media Thickness; D004730:Endothelium, Vascular / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006940:Hyperemia / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012859:Sjogren's Syndrome / Q000175:diagnosis* / Q000503:physiopathology*; D014664:Vasodilation / Q000502:physiology*