title: Successful cure of C1q deficiency in human subjects treated with hematopoietic stem cell transplantation.
authors.affiliation: Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom; Departments of Paediatric Immunology, Rheumatology and Bone Marrow Transplantation, Royal Manchester Children's Hospital, Manchester, United Kingdom. Electronic address: peter.arkwright@nhs.net.
authors.forename: Peter D
authors.initials: PD
authors.lastname: Arkwright
authors.affiliation: Departments of Paediatric Immunology, Rheumatology and Bone Marrow Transplantation, Royal Manchester Children's Hospital, Manchester, United Kingdom.
authors.forename: Philip
authors.initials: P
authors.lastname: Riley
authors.affiliation: Departments of Paediatric Immunology, Rheumatology and Bone Marrow Transplantation, Royal Manchester Children's Hospital, Manchester, United Kingdom.
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Hughes
authors.affiliation: Department of Immunology, Salford Royal Foundation Trust, Manchester, United Kingdom.
authors.forename: Hana
authors.initials: H
authors.lastname: Alachkar
authors.affiliation: Departments of Paediatric Immunology, Rheumatology and Bone Marrow Transplantation, Royal Manchester Children's Hospital, Manchester, United Kingdom.
authors.forename: Robert F
authors.initials: RF
authors.lastname: Wynn
mesh_terms: D000293:Adolescent; D000074323:Alemtuzumab; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage; D058846:Antibodies, Monoclonal, Murine-Derived / Q000008:administration & dosage; D001323:Autoantibodies / Q000097:blood; D002308:Cardiolipins / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D046528:Chimerism; D015922:Complement C1q / Q000235:genetics*; D003241:Consanguinity; D018572:Disease-Free Survival; D006086:Graft vs Host Disease / Q000209:etiology / Q000517:prevention & control*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000276:immunology / Q000628:therapy*; D008297:Male; D010154:Pakistan; D010375:Pedigree; D011183:Postoperative Complications / Q000517:prevention & control*; D020127:Recovery of Function; D012261:Ribonucleoproteins / Q000276:immunology; D000069283:Rituximab; D019172:Transplantation Conditioning / Q000379:methods; D000099207:SS-A Antigen
chemical_list: D000074323:Alemtuzumab; D061067:Antibodies, Monoclonal, Humanized; D058846:Antibodies, Monoclonal, Murine-Derived; D001323:Autoantibodies; D002308:Cardiolipins; D015922:Complement C1q; D012261:Ribonucleoproteins; D000069283:Rituximab; D000099207:SS-A Antigen