title: Quantitative wearable sensors for objective assessment of Parkinson's disease.
abstract: There is a rapidly growing interest in the quantitative assessment of Parkinson's disease (PD)-associated signs and disability using wearable technology. Both persons with PD and their clinicians see advantages in such developments. Specifically, quantitative assessments using wearable technology may allow for continuous, unobtrusive, objective, and ecologically valid data collection. Also, this approach may improve patient-doctor interaction, influence therapeutic decisions, and ultimately ameliorate patients' global health status. In addition, such measures have the potential to be used as outcome parameters in clinical trials, allowing for frequent assessments; eg, in the home setting. This review discusses promising wearable technology, addresses which parameters should be prioritized in such assessment strategies, and reports about studies that have already investigated daily life issues in PD using this new technology.
authors.affiliation: Hertie Institute for Clinical Brain Research, Department of Neurodegeneration, Center of Neurology, University of Tuebingen, Tuebingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany.
authors.forename: Walter
authors.initials: W
authors.lastname: Maetzler
authors.forename: Josefa
authors.initials: J
authors.lastname: Domingos
authors.forename: Karin
authors.initials: K
authors.lastname: Srulijes
authors.forename: Joaquim J
authors.initials: JJ
authors.lastname: Ferreira
authors.forename: Bastiaan R
authors.initials: BR
authors.lastname: Bloem
mesh_terms: D006233:Persons with Disabilities; D005684:Gait / Q000502:physiology*; D006801:Humans; D018670:Monitoring, Ambulatory / Q000295:instrumentation*; D010300:Parkinson Disease / Q000175:diagnosis* / Q000503:physiopathology
keywords: Parkinson's disease; outcomes; quantitative motor assessment; wearable devices