title: Optimizing reperfusion in patients with STEMI: a critical evaluation of pharmacologic and non-pharmacologic strategies.
abstract: Among patients with ST-elevation myocardial infarction (STEMI), rapidly re-establishing normal coronary blood flow is of paramount importance. More than 25 % of hospitals in the USA do not have access to timely primary percutaneous coronary intervention, highlighting the need for clinicians to understand both pharmacologic and non-pharmacologic strategies for STEMI. This manuscript reviews the current state of the art in STEMI care, describing both pharmacologic and non-pharmacologic strategies for reperfusion.
authors.affiliation: Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Interventional Cardiology Section, 1 Deaconess Road, Palmer 415, Boston, MA, 02215, USA.
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Yang
authors.forename: Duane S
authors.initials: DS
authors.lastname: Pinto
authors.forename: Anjan K
authors.initials: AK
authors.lastname: Chakrabarti
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000379:methods / Q000592:standards*; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D009203:Myocardial Infarction / Q000628:therapy*; D015425:Myocardial Reperfusion / Q000379:methods / Q000592:standards*; D016032:Randomized Controlled Trials as Topic / Q000379:methods / Q000592:standards; D015912:Thrombolytic Therapy / Q000379:methods / Q000592:standards*; D061665:Time-to-Treatment / Q000592:standards / Q000639:trends
chemical_list: D005343:Fibrinolytic Agents