title: A closer examination of atraumatic dressings for optimal healing.
abstract: The concept that undisturbed wound healing, optimised by dressing choice, improves wound outcomes has become a focal point of consideration when evaluating wound management regimens in recent years. However, little evidence exists related to wound contact layers and the potential detrimental effects of the intimate contact with the wound bed. The aim of this study was to evaluate the effects of atraumatic wound contact dressings on the healing of partial-thickness wounds in comparison to untreated air-exposed wounds. Using an in vivo porcine wound model the handling properties of each dressing in terms of adhesion were analysed. Methods of wound characterisation included histological analysis of granulation tissue formation and epithelialisation and this was correlated with various clinical observations. Differences were found between dressings in terms of adherence to the wound bed and surrounding skin, capacity to retain wound exudates and enhancement of healing.
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL,, USA.
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Davis
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL,, USA.
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL,, USA.
authors.forename: Joel
authors.initials: J
authors.lastname: Gil
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL,, USA.
authors.forename: Jose
authors.initials: J
authors.lastname: Valdes
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL,, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Solis
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL,, USA.
authors.forename: Ryan
authors.initials: R
authors.lastname: Treu
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL,, USA.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Kirnser
mesh_terms: D000818:Animals; D001458:Bandages; D004195:Disease Models, Animal; D005122:Exudates and Transudates; D005260:Female; D006097:Granulation Tissue / Q000473:pathology; D011091:Polyesters; D012828:Silicones; D012883:Skin Ulcer / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D013526:Surgical Mesh; D013552:Swine; D000267:Tissue Adhesions / Q000517:prevention & control*; D014945:Wound Healing / Q000502:physiology*; D014947:Wounds and Injuries / Q000209:etiology / Q000473:pathology / Q000628:therapy*
chemical_list: D011091:Polyesters; D012828:Silicones; C114834:mepitel
keywords: Adherence; Dressings; Porcine model; Wound healing
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