title: Asymmetric formation of tert-alkylamines from serinols by a dual function catalyst.
abstract: Consecutive intramolecular desymmetrization and kinetic resolution of 2-substituted N-phenoxycarbonylserinols have been achieved in one-pot by a single chiral catalyst, bisox)-CuCl2, to form oxazolidinones with remarkable enantioselectivities (94-99% ee) as tert-alkylamine building blocks. The process culminates in a dual-function of the chiral catalyst.
authors.affiliation: MIRC, Dept. of Chemistry, KAIST, Daejeon 305-701, Korea. shkang@kaist.ac.kr.
authors.forename: Young Suk
authors.initials: YS
authors.lastname: You
authors.forename: Tae Woo
authors.initials: TW
authors.lastname: Kim
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Kang