title: [A case on hemodialysis with castration-resistant prostate cancer which responded to combination chemotherapy with docetaxel and prednisolone].
abstract: A 71-year-old man on hemodialysis was admitted for castration-resistant prostate cancer. He received chemotherapy with docetaxel(60mg/m2 every 3 weeks)and prednisolone(10mg/day). As severe adverse reactions due to chemotherapy were not encountered, he could receive chemotherapy in our outpatient clinic. A total of four courses of chemotherapy resulted in a 56% reduction in PSA, which was judged as PR. Chemotherapy with docetaxel and prednisolone can be safely carried out for a patient with castration-resistant prostate cancer, even while on hemodialysis with the usual dose of docetaxel.
authors.affiliation: Dept. of Urology, University of Fukui, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ito
authors.forename: So
authors.initials: S
authors.lastname: Inamura
authors.forename: Minekatsu
authors.initials: M
authors.lastname: Taga
authors.forename: Katsuki
authors.initials: K
authors.lastname: Tsuchiyama
authors.forename: Naoya
authors.initials: N
authors.lastname: Kusukawa
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Oyama
authors.forename: Hironobu
authors.initials: H
authors.lastname: Akino
authors.forename: Osamu
authors.initials: O
authors.lastname: Yokoyama
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002369:Castration; D000077143:Docetaxel; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy*; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage; D011471:Prostatic Neoplasms / Q000150:complications / Q000188:drug therapy*; D006435:Renal Dialysis; D043823:Taxoids / Q000008:administration & dosage
chemical_list: D043823:Taxoids; D000077143:Docetaxel; D011239:Prednisolone