title: IgA nephropathy factors that predict and accelerate progression to end-stage renal disease.
abstract: IgA nephropathy (IgAN) or Berger's disease is a slowly progressing disease that leads to end-stage renal disease in 50 % of the patients within 25 years of the disease. However, several factors are associated with the accelerated progression of this disease causing early development of end-stage disease. Persistent proteinuria or hematuria, poorly controlled hypertension, elevated serum creatinine and prevalent glomerulosclerosis are some of the risk factors that expedite the deteriorative effects of IgAN. Thus, the progression of the disease can be delayed if the associated risk factors are handled and addressed in the nick of time.
authors.affiliation: Division of Nephrology, Affiliated Hospital of Chengde Medical College, Chengde, Hebei, China.
authors.forename: Lan
authors.initials: L
authors.lastname: Huang
authors.forename: Feng-Ling
authors.initials: FL
authors.lastname: Guo
authors.forename: Jin
authors.initials: J
authors.lastname: Zhou
authors.forename: Ya-Juan
authors.initials: YJ
authors.lastname: Zhao
mesh_terms: D015415:Biomarkers / Q000097:blood / Q000652:urine; D018450:Disease Progression; D005922:Glomerulonephritis, IGA / Q000097:blood / Q000150:complications* / Q000175:diagnosis* / Q000652:urine; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology*; D008019:Life Style; D011379:Prognosis
chemical_list: D015415:Biomarkers