title: Changes in cortical excitability and blood lactate after a fatiguing hand-grip exercise.
abstract: Excitability of primary hand motor cortex (PHMC), evaluated with transcranial magnetic stimulation by using the "1 mV resting motor threshold" method, and capillary blood lactate were measured at the end, as well as 5 and 10 min after a fatiguing hand-grip exercise. The relation between blood lactate and the amplitudes of motor-evoked potentials showed a significant direct proportionality. Blood lactate seems to exert a protective role on PHMC against fatigue reduction during extremely intensive isometric exercises.
authors.affiliation: Department of Bio-Medical Sciences, Università degli Studi di Catania , Italy .
authors.forename: Marinella
authors.initials: M
authors.lastname: Coco
authors.forename: Giovanna
authors.initials: G
authors.lastname: Alagona
authors.forename: Valentina
authors.initials: V
authors.lastname: Perciavalle
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Perciavalle
authors.forename: Paolo
authors.initials: P
authors.lastname: Cavallari
authors.forename: Antonio
authors.initials: A
authors.lastname: Caronni
mesh_terms: D000328:Adult; D002540:Cerebral Cortex / Q000502:physiology*; D019054:Evoked Potentials, Motor / Q000502:physiology*; D018737:Hand Strength; D006801:Humans; D007537:Isometric Contraction / Q000502:physiology*; D019344:Lactic Acid / Q000097:blood*; D008297:Male; D018763:Muscle Fatigue / Q000502:physiology*; D050781:Transcranial Magnetic Stimulation
chemical_list: D019344:Lactic Acid