title: Does organic material on hospital surfaces reduce the effectiveness of hypochlorite and UV radiation for disinfection of Clostridium difficile?
abstract: An organic load of 5%-10% fetal calf serum significantly reduced hypochlorite and UV radiation killing of Clostridium difficile spores, but organic material collected from hospital surfaces did not affect hypochlorite and only modestly affected UV killing of spores. Hypochlorite reduced aerobic microorganisms on unclean surfaces with no wiping.
authors.affiliation: Case Western Reserve University School of Medicine, Cleveland, Ohio.
authors.forename: Andrew
authors.initials: A
authors.lastname: Zhang
authors.forename: Michelle M
authors.initials: MM
authors.lastname: Nerandzic
authors.forename: Sirisha
authors.initials: S
authors.lastname: Kundrapu
authors.forename: Curtis J
authors.initials: CJ
authors.lastname: Donskey
mesh_terms: D000818:Animals; D002417:Cattle; D016360:Clostridioides difficile / Q000187:drug effects / Q000528:radiation effects; D003428:Cross Infection / Q000517:prevention & control; D004202:Disinfectants / Q000494:pharmacology*; D004203:Disinfection / Q000379:methods*; D004761:Enterocolitis, Pseudomembranous / Q000517:prevention & control; D004866:Equipment Contamination / Q000517:prevention & control; D006801:Humans; D010362:Patients' Rooms; D044967:Serum; D012973:Sodium Hypochlorite / Q000494:pharmacology*; D013171:Spores, Bacterial; D014466:Ultraviolet Rays
chemical_list: D004202:Disinfectants; D012973:Sodium Hypochlorite