title: [A case of advanced gastric cancer with tumor embolus in portal vein successfully treated by neoadjuvant chemotherapy, operation and chemoradiotherapy].
abstract: A 66-year-old man was admitted to our hospital with a diagnosis of advanced gastric cancer, with a tumor embolus in the portal vein and lymph node metastases. Since curative surgery was deemed impossible, we started neoadjuvant chemotherapy using S-1 plus CDDP. After 1 course of chemotherapy, the embolus in the portal vein disappeared. After additional chemotherapy, the primary tumor and lymph nodes were reduced in size, and a total gastrectomy with splenectomy and lymph node dissection was performed. Although he received S-1 medication as adjuvant chemotherapy, a tumor embolus in the portal vein appeared 8 months after the operation. Chemoradiotherapy(S-1+total of 50.4 Gy)was performed and the tumor embolus disappeared.
authors.affiliation: Dept. of Surgery, Toyohashi Medical Center, Japan.
authors.forename: Naohiro
authors.initials: N
authors.lastname: Nomura
authors.forename: Katsuya
authors.initials: K
authors.lastname: Yamashita
authors.forename: Hiroki
authors.initials: H
authors.lastname: Uchida
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Muto
authors.forename: Kiichiro
authors.initials: K
authors.lastname: Okamoto
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Sato
authors.forename: Toru
authors.initials: T
authors.lastname: Ichihara
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D059248:Chemoradiotherapy; D002945:Cisplatin / Q000008:administration & dosage; D004338:Drug Combinations; D004617:Embolism / Q000209:etiology*; D006801:Humans; D008297:Male; D020360:Neoadjuvant Therapy; D010094:Oxonic Acid / Q000008:administration & dosage; D011169:Portal Vein / Q000473:pathology*; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin