title: Eco-geographical differentiation among Colombian populations of the Chagas disease vector Triatoma dimidiata (Hemiptera: Reduviidae).
abstract: Triatoma dimidiata is currently the main vector of Chagas disease in Mexico, most Central American countries and several zones of Ecuador and Colombia. Although this species has been the subject of several recent phylogeographic studies, the relationship among different populations within the species remains unclear. To elucidate the population genetic structure of T. dimidiata in Colombia, we analyzed individuals from distinct geographical locations using the cytochrome c oxidase subunit 1 gene and 7 microsatellite loci. A clear genetic differentiation was observed among specimens from three Colombian eco-geographical regions: Inter Andean Valleys, Caribbean Plains and Sierra Nevada de Santa Marta mountain (SNSM). Additionally, evidence of genetic subdivision was found within the Caribbean Plains region as well as moderate gene flow between the populations from the Caribbean Plains and SNSM regions. The genetic differentiation found among Colombian populations correlates, albeit weakly, with an isolation-by-distance model (IBD). The genetic heterogeneity among Colombian populations correlates with the eco-epidemiological and morphological traits observed in this species across regions within the country. Such genetic and epidemiological diversity should be taken into consideration for the development of vector control strategies and entomological surveillance.
authors.affiliation: Grupo BCEI, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellin, Colombia. Electronic address: amgomezpa@gmail.com.
authors.forename: Andrés
authors.initials: A
authors.lastname: Gómez-Palacio
authors.forename: Omar
authors.initials: O
authors.lastname: Triana
authors.forename: Nicolás
authors.initials: N
authors.lastname: Jaramillo-O
authors.forename: Ellen M
authors.initials: EM
authors.lastname: Dotson
authors.forename: Paula L
authors.initials: PL
authors.lastname: Marcet
mesh_terms: D000818:Animals; D014355:Chagas Disease / Q000453:epidemiology / Q000635:transmission*; D003105:Colombia / Q000453:epidemiology; D003576:Electron Transport Complex IV / Q000235:genetics*; D051456:Gene Flow; D014644:Genetic Variation; D006801:Humans; D007303:Insect Vectors / Q000145:classification / Q000235:genetics / Q000469:parasitology; D018895:Microsatellite Repeats / Q000235:genetics*; D014224:Triatoma / Q000145:classification / Q000235:genetics* / Q000469:parasitology*; D014349:Trypanosoma cruzi / Q000472:pathogenicity
chemical_list: D003576:Electron Transport Complex IV
keywords: Chagas disease; Cytochrome c oxidase subunit 1; Multilocus microsatellite analysis; Population genetics; Triatoma dimidiata; Triatominae
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