title: A general strategy for the synthesis of P-stereogenic compounds.
abstract: A great leap forward toward the general synthesis of P-stereogenic compounds: Heating H3 PO2 with (-)-menthol and paraformaldehyde gives easily crystallized menthyl hydroxymethyl-H-phosphinate (1). From this product, virtually any P-stereogenic compound can be synthesized.
authors.affiliation: Department of Chemistry, Box 298860, Texas Christian University, Fort Worth, TX 76133 (USA).
authors.forename: Olivier
authors.initials: O
authors.lastname: Berger
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Montchamp
keywords: H-phosphinates; chiral auxiliaries; menthol; organophosphorus compounds; phosphinates