title: Effect of surgical staging on 539 patients with borderline ovarian tumors: a Turkish Gynecologic Oncology Group study.
abstract: OBJECTIVE
  The objectives of this study were to examine demographic and clinicopathologic characteristics and to determine the effects of primary surgery, surgical staging and the extensiveness of staging.
  
  
  METHODS
  In a retrospective Turkish multicenter study, 539 patients, from 14 institutions, with borderline ovarian tumors were investigated. Some of the demographic, clinical and surgical characteristics of the cases were evaluated. The effects of type of surgery, surgical staging; complete or incomplete staging on survival rates were calculated by using Kaplan-Meier method.
  
  
  RESULTS
  The median age at diagnosis was 40 years (range 15-84) and 71.1% of patients were premenopausal. The most common histologic types were serous and mucinous. Majority of the staged cases were in Stage IA (73.5%). 242 patients underwent conservative surgery. Recurrence rates were significantly higher in conservative surgery group (8.3% vs. 3%). Of all patients in this study, 294 (54.5%) have undergone surgical staging procedures. Of the patients who underwent surgical staging, 228 (77.6%) had comprehensive staging including lymphadenectomy. Appendectomy was performed on 204 (37.8%) of the patients. The median follow-up time was 36 months (range 1-120 months). Five-year survival rate was 100% and median survival time was 120 months. Surgical staging, lymph node sampling or dissection and appendectomy didn't cause any difference on survival.
  
  
  CONCLUSIONS
  Comprehensive surgical staging, lymph node sampling or dissection and appendectomy are not beneficial in borderline ovarian tumors surgical management.
authors.affiliation: Celal Bayar University School of Medicine, Department of Obstetrics and Gynecology, Manisa, Turkey. Electronic address: tguvenal@yahoo.com.
authors.forename: Tevfik
authors.initials: T
authors.lastname: Guvenal
authors.forename: Polat
authors.initials: P
authors.lastname: Dursun
authors.forename: Pinar S
authors.initials: PS
authors.lastname: Hasdemir
authors.forename: Merih
authors.initials: M
authors.lastname: Hanhan
authors.forename: Suleyman
authors.initials: S
authors.lastname: Guven
authors.forename: Hakan
authors.initials: H
authors.lastname: Yetimalar
authors.forename: Behice P
authors.initials: BP
authors.lastname: Goksedef
authors.forename: Derya K
authors.initials: DK
authors.lastname: Sakarya
authors.forename: Arzu
authors.initials: A
authors.lastname: Doruk
authors.forename: Mustafa C
authors.initials: MC
authors.lastname: Terek
authors.forename: Bahadir
authors.initials: B
authors.lastname: Saatli
authors.forename: Kadir
authors.initials: K
authors.lastname: Guzin
authors.forename: Aydin
authors.initials: A
authors.lastname: Corakci
authors.forename: Emek
authors.initials: E
authors.lastname: Deger
authors.forename: Husnu
authors.initials: H
authors.lastname: Celik
authors.forename: Ahmet
authors.initials: A
authors.lastname: Cetin
authors.forename: Aydin
authors.initials: A
authors.lastname: Ozsaran
authors.forename: Ayşe
authors.initials: A
authors.lastname: Ozbakkaloglu
authors.forename: Ali
authors.initials: A
authors.lastname: Kolusari
authors.forename: Cetin
authors.initials: C
authors.lastname: Celik
authors.forename: Refik
authors.initials: R
authors.lastname: Keles
authors.forename: Fulya G
authors.initials: FG
authors.lastname: Sagir
authors.forename: Saffet
authors.initials: S
authors.lastname: Dilek
authors.forename: Turhan
authors.initials: T
authors.lastname: Uslu
authors.forename: Yilmaz
authors.initials: Y
authors.lastname: Dikmen
authors.forename: Ozden
authors.initials: O
authors.lastname: Altundag
authors.forename: Ali
authors.initials: A
authors.lastname: Ayhan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001062:Appendectomy; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology / Q000601:surgery; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000473:pathology; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery*; D012189:Retrospective Studies; D014421:Turkey / Q000453:epidemiology; D055815:Young Adult
keywords: Appendectomy; Borderline; Lymphadenectomy; Ovarian tumor; Surgical staging