title: Micropulse diode laser treatment for chronic central serous chorioretinopathy: a randomized pilot trial.
abstract: OBJECTIVE
  To evaluate 810-nm subthreshold diode micropulse (SDM) laser in patients with chronic central serous chorioretinopathy (CSC).
  
  
  METHODS
  Prospective, randomized, double-blind, sham-controlled pilot trial. Patients were randomized to SDM laser treatment (group 1) or sham procedure (group 2). Primary outcome measure was change in best corrected visual acuity (BCVA); secondary outcome was central macular thickness after 3 months. Laser treatment was performed along the detached area. At the 3-month visit, all patients were evaluated for re-treatment if they met re-treatment criteria.
  
  
  RESULTS
  Fifteen patients were included in this study: five patients in the sham group and 10 in the treatment group. At 3 months, BCVA was significantly enhanced in the treatment group (P = .006) compared with the sham group (P = .498). All patients from the sham group needed treatment after 3 months. An improvement in central macular thickness and leakage on fluorescein angiography was noted in all treated patients (in both groups).
  
  
  CONCLUSIONS
  In this limited-size, short-term exploratory study, SDM laser was effective in treating chronic CSC. There was no evidence of retinal damage induced by treatment.
authors.forename: Luiz
authors.initials: L
authors.lastname: Roisman
authors.forename: Fernanda Pedreira
authors.initials: FP
authors.lastname: Magalhães
authors.forename: Daniel
authors.initials: D
authors.lastname: Lavinsky
authors.forename: Nilva
authors.initials: N
authors.lastname: Moraes
authors.forename: Flávio E
authors.initials: FE
authors.lastname: Hirai
authors.forename: José Augusto
authors.initials: JA
authors.lastname: Cardillo
authors.forename: Michel Eid
authors.initials: ME
authors.lastname: Farah
mesh_terms: D000328:Adult; D056833:Central Serous Chorioretinopathy / Q000601:surgery*; D002908:Chronic Disease; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D017075:Laser Coagulation / Q000379:methods*; D054023:Lasers, Semiconductor; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011446:Prospective Studies; D014792:Visual Acuity