title: The effect of cognitive status and visuospatial performance on affective theory of mind in Parkinson's disease.
abstract: It is now well accepted that theory of mind (ToM) functioning is impaired in Parkinson's disease (PD) patients. However, what remain unknown are the functions that underlie this impairment. It has been suggested that cognitive skills may be key in this area of functioning; however, many of the cognitive tests used to assess this have relied on intact visuospatial abilities. This study aimed to examine whether deficits in ToM were generated by cognitive or visuospatial dysfunction and the mediating effect of visuospatial function on ToM performance. Fifty PD patients (31 male, 19 female; mean age = 66.34 years) and 49 healthy controls (16 male, 33 female; mean age = 67.29 years) completed a ToM task (reading the mind in the eyes) and visuospatial task (line orientation). The results revealed that current cognitive status was a significant predictor for performance on the ToM task, and that 54% of the total effect of cognitive status on ToM was mediated by visuospatial abilities. It was concluded that visuospatial functioning plays an important mediating role for the relationship between executive dysfunction and affective ToM deficits in PD patients, and that visuospatial deficits may directly contribute to the presence of affective ToM difficulties seen in individuals with PD.
authors.affiliation: Department of Psychology, University of Canterbury, Christchurch, New Zealand ; Department of Psychology and Psychiatry, Monash University, Clayton, VIC, Australia.
authors.forename: Audrey
authors.initials: A
authors.lastname: McKinlay
authors.forename: Michelle
authors.initials: M
authors.lastname: Albicini
authors.forename: Phillip S
authors.initials: PS
authors.lastname: Kavanagh
keywords: Parkinson’s disease; executive function; social cognition; theory of mind; visuospatial function
references.citation: Am J Phys Med Rehabil. 1997 Sep-Oct;76(5):383-8
references.pmid: 9354492
references.citation: J Int Neuropsychol Soc. 2010 Mar;16(2):268-77
references.pmid: 20003582
references.citation: Br J Psychol. 2002 Nov;93(Pt 4):465-85
references.pmid: 12519529
references.citation: Neuropsychologia. 2005;43(4):598-608
references.pmid: 15716150
references.citation: Parkinsonism Relat Disord. 2012 Jan;18(1):21-4
references.pmid: 21868278
references.citation: Cortex. 2009 Sep;45(8):972-81
references.pmid: 19371867
references.citation: Parkinsonism Relat Disord. 2011 May;17(4):246-8
references.pmid: 20889365
references.citation: J Child Psychol Psychiatry. 2001 Feb;42(2):241-51
references.pmid: 11280420
references.citation: Cogn Neuropsychiatry. 2003 Aug;8(3):191-209
references.pmid: 16571560
references.citation: J Int Neuropsychol Soc. 2000 Nov;6(7):781-8
references.pmid: 11105468
references.citation: Neurology. 2001 Nov;57(10 Suppl 3):S11-26
references.pmid: 11775596
references.citation: Behav Brain Res. 2011 Jun 1;219(2):342-50
references.pmid: 21238496
references.citation: Neuropsychology. 2013 Jan;27(1):37-47
references.pmid: 23356595
references.citation: Psychol Med. 2012 Nov;42(11):2445-52
references.pmid: 22440401
references.citation: Mov Disord. 2012 Jan;27(1):98-105
references.pmid: 21915910
references.citation: Psychol Aging. 2002 Dec;17(4):598-609
references.pmid: 12507357
references.citation: J Clin Psychiatry. 1987 Aug;48(8):314-8
references.pmid: 3611032
references.citation: Parkinsonism Relat Disord. 2010 Aug;16(7):466-70
references.pmid: 20538499
references.citation: Neuropsychologia. 2009 Jan;47(2):406-14
references.pmid: 18845171
references.citation: Arch Neurol. 1978 Jun;35(6):364-7
references.pmid: 655909
references.citation: Parkinsonism Relat Disord. 2006 Apr;12(3):169-75
references.pmid: 16563850