title: Organocatalyzed asymmetric synthesis of dihydrodibenzofurans based on a dienamine process.
abstract: The first organocatalyzed asymmetric method for the synthesis of dihydrodibenzofurans based on a dienamine process has been developed. This two-step protocol works with a broad range of substrates and delivers only the cis-diastereomer in good yield with up to 91% ee. The enantioenriched products have been transformed to highly functionalized and partially hydrogenated dibenzofurans in excellent diastereoselectivities.
authors.affiliation: Department of Chemistry, The University of Hong Kong , Pokfulam Road, Hong Kong, P. R. China.
authors.forename: Zi-Yu
authors.initials: ZY
authors.lastname: Wang
authors.forename: Wing-Tak
authors.initials: WT
authors.lastname: Wong
authors.forename: Dan
authors.initials: D
authors.lastname: Yang
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006865:Hydrogenation; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001572:Benzofurans