title: Diagnostic role of computed tomographic enterography differentiating crohn disease from intestinal tuberculosis.
abstract: OBJECTIVE
  The aim of the present study was to evaluate the diagnostic role of computed tomographic enterography (CTE) in distinguishing Crohn disease (CD) from intestinal tuberculosis (ITB).
  
  
  METHODS
  From January 2006 to August 2011, a total of 81 consecutive patients (64 patients with CD and 17 patients with ITB) who received CTE on the initial workup were included. In CTE, degree of bowel involvement (number and length), mural change (mural hyperenhancement, stratification, wall thickening, and distribution), adjacent mesenteric change (comb sign, fibrofatty proliferation, fistula, abscess, and lymphadenopathy), and peritoneal change (peritoneal thickening and ascites) were assessed.
  
  
  RESULTS
  Segmental involvement, comb sign, fibrofatty changes, moderate wall thickening, and asymmetric distribution were significantly more common in the patients with CD than those with ITB. A positive comb sign was the most suggestive finding of CD (sensitivity, 74.1%; specificity, 90.9%).
  
  
  CONCLUSIONS
  A positive comb sign is the most suggestive finding that differentiates CD from ITB.
authors.affiliation: From the *Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul; †Department of Diagnostic Radiology, Konyang University Hospital, Konyang University College of Medicine, Daejon; and ‡Department of Radiology, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Yoon Hea
authors.initials: YH
authors.lastname: Park
authors.forename: Woo-Suk
authors.initials: WS
authors.lastname: Chung
authors.forename: Joon Seok
authors.initials: JS
authors.lastname: Lim
authors.forename: Soo Jung
authors.initials: SJ
authors.lastname: Park
authors.forename: Jae Hee
authors.initials: JH
authors.lastname: Cheon
authors.forename: Tae Il
authors.initials: TI
authors.lastname: Kim
authors.forename: Won Ho
authors.initials: WH
authors.lastname: Kim
authors.forename: Sung Pil
authors.initials: SP
authors.lastname: Hong
mesh_terms: D000328:Adult; D000368:Aged; D003424:Crohn Disease / Q000453:epidemiology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D015203:Reproducibility of Results; D056910:Republic of Korea / Q000453:epidemiology; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data*; D014385:Tuberculosis, Gastrointestinal / Q000175:diagnosis* / Q000453:epidemiology*; D055815:Young Adult