title: Biogenic growth of alloys and core-shell nanostructures using urease as a nanoreactor at ambient conditions.
abstract: Biomineralization is an extremely efficient biologically guided process towards the advancement of nano-bio integrated materials. As a prime module of the natural world, enzymes are expected to play a major role in biogenic growth of inorganic nanostructures. Although there have been developments in designing enzyme-responsive nanoparticle systems or generation of inorganic nanostructures in an enzyme-stimulated environment, reports regarding action of enzymes as reducing agents themselves for the growth of inorganic nanoparticles still remains elusive. Here we present a mechanistic investigation towards the synthesis of metal and metallic alloy nanoparticles using a commonly investigated enzyme, Jack bean urease (JBU), as a reducing as well as stabilizing agent under physiological conditions. The catalytic functionality of urease was taken advantage of towards the development of metal-ZnO core-shell nanocomposites, making urease an ideal bionanoreactor for synthesizing higher order nanostructures such as alloys and core- shell under ambient conditions.
authors.affiliation: Discipline of Chemistry, School of Basic Sciences, Indian Institute of Technology Indore, IET Campus, DAVV, Khandwa Road, Indore 452017, INDIA.
authors.forename: Bhagwati
authors.initials: B
authors.lastname: Sharma
authors.forename: Sonam
authors.initials: S
authors.lastname: Mandani
authors.forename: Tridib K
authors.initials: TK
authors.lastname: Sarma
mesh_terms: D000497:Alloys / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D053768:Metal Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D014510:Urease / Q000737:chemistry*; D015034:Zinc Oxide / Q000737:chemistry
chemical_list: D000497:Alloys; D014510:Urease; D015034:Zinc Oxide
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