title: Surgical outcomes after application of a liquid adhesive ocular bandage to clear corneal incisions during cataract surgery.
abstract: OBJECTIVE
  To compare the anatomic and refractive outcomes in eyes having phacoemulsification with 1 of 3 clear corneal incision (CCI) closure methods.
  
  
  METHODS
  Ambulatory surgical center, Makati, Philippines.
  
  
  METHODS
  Prospective randomized clinical trial.
  
  
  METHODS
  Patients having phacoemulsification cataract surgery had wound closure using no additional treatment (control), a single 10-0 nylon suture, or a liquid adhesive ocular bandage (Ocuseal). The main outcome measures were wound-edge closure rates, surgically induced astigmatism (SIA), foreign-body sensation, and intraocular pressure (IOP) 1, 3, 5, 7, and 14 days postoperatively.
  
  
  RESULTS
  The study evaluated 90 eyes. There was a significant improvement in wound-edge closure rates in the suture group and the ocular bandage group compared with the control group (P<.001). A significant increase in SIA occurred in the sutured group but not in the control or ocular bandage groups (P<.001). The ocular bandage group had significantly less foreign-body sensation than the control and suture groups (P<.001). There were no significant differences in IOP between the groups (P=.515).
  
  
  CONCLUSIONS
  The liquid adhesive ocular bandage resulted in improved wound-edge closure, reduced SIA, and diminished foreign-body sensation. Suturing was associated with improved wound-edge closure but increased SIA and foreign-body sensation. Unsutured incisions led to delayed wound-edge closure and increased foreign-body sensation.
authors.affiliation: From Philippine General Hospital (Uy), University of the Philippines, Manila, St. Luke's Medical Center (Uy), Quezon City, and the Pacific Eye and Laser Institute (Uy), Makati, Philippines; Harvard Medical School, Tufts University School of Medicine, and Schepens Eye Research Institute (Kenyon), Boston, Massachusetts, USA. Electronic address: harveyuy@yahoo.com.
authors.forename: Harvey S
authors.initials: HS
authors.lastname: Uy
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Kenyon
mesh_terms: D000368:Aged; D001251:Astigmatism / Q000503:physiopathology; D047070:Bandages, Hydrocolloid; D001699:Biometry; D003315:Cornea / Q000187:drug effects* / Q000503:physiopathology / Q000601:surgery; D004728:Endothelium, Corneal / Q000473:pathology; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D007429:Intraocular Pressure / Q000502:physiology; D019654:Lens Implantation, Intraocular; D008875:Middle Aged; D018918:Phacoemulsification; D011446:Prospective Studies; D013536:Suture Techniques; D014014:Tissue Adhesives / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D014014:Tissue Adhesives; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate