title: Caregiver burden in frontotemporal degeneration and corticobasal syndrome.
abstract: OBJECTIVE
  Caregiver stress is often a serious problem when caring for a patient with frontal lobe dysfunction.
  
  
  METHODS
  A total of 102 caregivers of both patients with frontotemporal degeneration and corticobasal syndrome completed the Frontal Systems Behavior Scale (FrSBe) and the Zarit Burden Interview (ZBI). To analyze the association between apathy or disinhibition (or both) and caregiver burden, the effects of the total FrSBe and the apathy and disinhibition subscales of the FrSBE on the total ZBI score were assessed with logistic regressions and t tests.
  
  
  RESULTS
  Total FrSBE score and the apathy FrSBE subscore predicted caregiver burden. Apathy occurred without disinhibition, and the two occurred together, but disinhibition without apathy was very rare.
  
  
  CONCLUSIONS
  Disinhibition without apathy occurred very rarely. Apathy was more associated with caregiver burden than disinhibition.
authors.affiliation: Department of Epidemiology, Mailman School of Public Health, New York, N.Y., USA.
authors.forename: Nicole
authors.initials: N
authors.lastname: Armstrong
authors.forename: Nicole
authors.initials: N
authors.lastname: Schupf
authors.forename: Jordan
authors.initials: J
authors.lastname: Grafman
authors.forename: Edward D
authors.initials: ED
authors.lastname: Huey
mesh_terms: D000223:Adaptation, Psychological; D057565:Apathy; D017028:Caregivers / Q000523:psychology*; D017281:Cost of Illness; D056344:Executive Function; D005260:Female; D057180:Frontotemporal Dementia / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D016015:Logistic Models; D008297:Male; D019636:Neurodegenerative Diseases / Q000175:diagnosis / Q000628:therapy*; D009784:Occupational Diseases / Q000523:psychology*; D013315:Stress, Psychological / Q000523:psychology*; D011795:Surveys and Questionnaires; D013577:Syndrome
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