title: Assessment of antimicrobial potential of 10% ginger extract against Streptococcus mutans, Candida albicans, and Enterococcus faecalis: an in vitro study.
abstract: BACKGROUND
  Streptococcus mutans, Candida albicans, and Enterococcus faecalis are the three oral microorganisms most commonly implicated in the causation of oral infections. All these oral microorganisms have shown resistant to routinely used antimicrobials. There is a need for an antimicrobial agent which is effective, safe, and economical. Zingiber officinale, commonly known as ginger is one such plant product which has been used from ancient time. It has been shown to possess promising inhibitory effect on many of the oral microorganisms. On review of dental literature, there was scarcity of studies which had tried to assess antimicrobial potential of ginger extract against S. mutans, E. faecalis, and C. albicans; hence, the present study was designed.
  
  
  OBJECTIVE
  To evaluate the in vitro antimicrobial potential of 10% ginger extract against S. mutans, E. faecalis, and C. albicans.
  
  
  METHODS
  Laboratory setting and experimental design.
  
  
  METHODS
  In the first part of the study, 10% ethanolic ginger extract was prepared in the laboratory of Pharmacy College. It was then subjected to microbiological assay to determine its zone of inhibition using Agar disk diffusion test and minimum inhibitory concentration (MIC) using serial broth dilution method against S. mutans, C. albicans, and E. faecalis.
  
  
  RESULTS
  10% ethanolic ginger extract showed: (a) Maximum zone of inhibition of 8 mm, 14 mm, and 11 mm against S. mutans, C. albicans, and E. faecalis respectively. (b) MIC of 1.25%, 2.5%, and 2.5% against S. mutans, C. albicans, and E. faecalis respectively.
  
  
  CONCLUSIONS
  10% ethanolic ginger extract was found to possess antimicrobial potential against all the three pathogens used in the study.
authors.affiliation: Department of Public Health Dentistry, Bapuji Dental College, Davangere, Karnataka, India.
authors.forename: Anjan
authors.initials: A
authors.lastname: Giriraju
authors.forename: G Y
authors.initials: GY
authors.lastname: Yunus
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D013293:Enterococcus faecalis / Q000187:drug effects*; D020939:Zingiber officinale / Q000737:chemistry*; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D013295:Streptococcus mutans / Q000187:drug effects*
chemical_list: D000890:Anti-Infective Agents; D010936:Plant Extracts