title: Surgical resection of hepatic metastasis from gastric cancer:  a review and new recommendation in the Japanese gastric cancer  treatment guidelines.
abstract: Liver metastases from gastric cancer are rarely indicated for surgery because they are often diagnosed as multiple nodules occupying both lobes and coexist with extra hepatic disease. A literature search identified no clinical trials on hepatectomy for this disease; only retrospective studies of a relatively small number of cases collected over more than a decade, mostly from a single institution, were found. Five-year survival rates from these reports ranged from 0 % to 37 %, and long-term survivors were observed among carefully selected case series. The most commonly reported prognostic factor was the number of metastatic nodules, and patients with a solitary metastasis tended to have superior outcome. Patients diagnosed to have a small number of metastatic nodules by modern imaging tools could be indicated for surgery. Because both intrahepatic and extrahepatic recurrences are common,patients are likely to benefit from perioperative adjuvant chemotherapy, although it is not possible at this time to specify which regimen is the most appropriate
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Kodera
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Fujitani
authors.forename: Norimasa
authors.initials: N
authors.lastname: Fukushima
authors.forename: Seiji
authors.initials: S
authors.lastname: Ito
authors.forename: Kei
authors.initials: K
authors.lastname: Muro
authors.forename: Norifumi
authors.initials: N
authors.lastname: Ohashi
authors.forename: Takaki
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kobayashi
authors.forename: Chie
authors.initials: C
authors.lastname: Tanaka
authors.forename: Michitaka
authors.initials: M
authors.lastname: Fujiwara
mesh_terms: D006498:Hepatectomy / Q000592:standards*; D006801:Humans; D007564:Japan; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery*; D017410:Practice Guidelines as Topic; D011379:Prognosis; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*
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