title: A systematic review of the effects of different types of therapeutic exercise on physiologic and functional measurements in patients with HIV/AIDS.
abstract: Several studies have reported the benefits of exercise training for adults with HIV, although there is no consensus regarding the most efficient modalities. The aim of this study was to determine the effects of different types of exercise on physiologic and functional measurements in patients with HIV using a systematic strategy for searching randomized controlled trials. The sources used in this review were the Cochrane Library, EMBASE, MEDLINE, and PEDro from 1950 to August 2012. We selected randomized controlled trials examining the effects of exercise on body composition, muscle strength, aerobic capacity, and/or quality of life in adults with HIV. Two independent reviewers screened the abstracts using the Cochrane Collaboration's protocol. The PEDro score was used to evaluate methodological quality. In total, 29 studies fulfilled the inclusion criteria. Individual studies suggested that exercise training contributed to improvement of physiologic and functional parameters, but that the gains were specific to the type of exercise performed. Resistance exercise training improved outcomes related to body composition and muscle strength, with little impact on quality of life. Aerobic exercise training improved body composition and aerobic capacity. Concurrent training produced significant gains in all outcomes evaluated, although moderate intensity and a long duration were necessary. We concluded that exercise training was shown to be a safe and beneficial intervention in the treatment of patients with HIV.
authors.affiliation: Departamento de Biofunção, Curso de Fisioterapia, Universidade Federal da Bahia (UFBA), SalvadorBA, Brazil.
authors.forename: Mansueto
authors.initials: M
authors.lastname: Gomes-Neto
authors.forename: Cristiano Sena
authors.initials: CS
authors.lastname: Conceição
authors.forename: Vitor
authors.initials: V
authors.lastname: Oliveira Carvalho
authors.forename: Carlos
authors.initials: C
authors.lastname: Brites
mesh_terms: D015444:Exercise / Q000502:physiology*; D005081:Exercise Therapy; D005260:Female; D015658:HIV Infections / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D008297:Male; D016032:Randomized Controlled Trials as Topic; D012016:Reference Values; D013997:Time Factors; D016896:Treatment Outcome
references.citation: Cochrane Database Syst Rev. 2004 Oct 18;(4):CD004248
references.pmid: 15495092
references.citation: J Altern Complement Med. 2005 Dec;11(6):1085-92
references.pmid: 16398601
references.citation: J Acquir Immune Defic Syndr. 2005 Apr 1;38(4):399-406
references.pmid: 15764956
references.citation: J Clin Endocrinol Metab. 1999 Apr;84(4):1268-76
references.pmid: 10199766
references.citation: AIDS Res Hum Retroviruses. 2008 Jan;24(1):15-23
references.pmid: 18275343
references.citation: Med Sci Sports Exerc. 1992 Jan;24(1):6-12
references.pmid: 1548998
references.citation: AIDS. 2001 Dec 7;15(18):2431-40
references.pmid: 11740194
references.citation: Arch Phys Med Rehabil. 1990 Aug;71(9):644-8
references.pmid: 2375667
references.citation: Med Sci Sports Exerc. 2000 Jun;32(6):1175-84
references.pmid: 10862549
references.citation: Med Sci Sports Exerc. 2006 Mar;38(3):411-7
references.pmid: 16540826
references.citation: Int J Sports Med. 1999 Feb;20(2):142-6
references.pmid: 10190777
references.citation: Int J Sports Med. 2007 Dec;28(12):1046-52
references.pmid: 17549659
references.citation: Eur J Appl Physiol. 2002 Nov;88(1-2):50-60
references.pmid: 12436270
references.citation: AIDS Care. 2008 Oct;20(9):1066-74
references.pmid: 18608063
references.citation: J Assoc Nurses AIDS Care. 2003 Mar-Apr;14(2):30-40
references.pmid: 12698764
references.citation: Med Sci Sports Exerc. 1999 Jul;31(7):973-9
references.pmid: 10416558
references.citation: AIDS. 2001 Apr 13;15(6):693-701
references.pmid: 11371683
references.citation: Med Sci Sports Exerc. 2011 Jul;43(7):1334-59
references.pmid: 21694556
references.citation: Qual Life Res. 2008 Apr;17(3):377-85
references.pmid: 18320351
references.citation: Aust J Physiother. 2006;52(3):185-90
references.pmid: 16942453
references.citation: J Clin Epidemiol. 1998 Dec;51(12):1235-41
references.pmid: 10086815
references.citation: AIDS Care. 2008 Jul;20(6):631-53
references.pmid: 18576165
references.citation: Arch Intern Med. 2006 Jun 12;166(11):1225-31
references.pmid: 16772251
references.citation: J Assoc Nurses AIDS Care. 2002 Mar-Apr;13(2):33-45
references.pmid: 11936063
references.citation: AIDS. 2004 Feb 20;18(3):465-73
references.pmid: 15090799
references.citation: Med Sci Sports Exerc. 2006 Nov;38(11):1939-44
references.pmid: 17095927
references.citation: AIDS. 1996 Jun;10(6):667-73
references.pmid: 8780822
references.citation: PLoS One. 2009;4(2):e4605
references.pmid: 19242554
references.citation: Med Sci Sports Exerc. 2003 Mar;35(3):456-64
references.pmid: 12618576
references.citation: Ann Intern Med. 2000 Sep 5;133(5):348-55
references.pmid: 10979879
references.citation: Med Care. 2000 Dec;38(12):1210-23
references.pmid: 11186300
references.citation: Am J Physiol Endocrinol Metab. 2011 Jan;300(1):E243-51
references.pmid: 20959530
references.citation: J Clin Endocrinol Metab. 2004 May;89(5):2171-8
references.pmid: 15126538
references.citation: Biofeedback Self Regul. 1990 Sep;15(3):229-42
references.pmid: 2223891
references.citation: J Clin Endocrinol Metab. 2008 Oct;93(10):3860-9
references.pmid: 18628529
references.citation: Eur J Appl Physiol. 2003 Mar;89(1):42-52
references.pmid: 12627304
references.citation: JAMA. 1999 Apr 14;281(14):1282-90
references.pmid: 10208143
references.citation: Sports Med. 2004;34(8):487-99
references.pmid: 15248786
references.citation: Phys Ther. 2003 Aug;83(8):713-21
references.pmid: 12882612
references.citation: Med Sci Sports Exerc. 2001 Oct;33(10):1751-8
references.pmid: 11581562
references.citation: AIDS Patient Care STDS. 2004 Feb;18(2):81-98
references.pmid: 15006183
references.citation: Circulation. 2001 Oct 2;104(14):1694-740
references.pmid: 11581152
references.citation: JAMA. 2000 Feb 9;283(6):763-70
references.pmid: 10683055
references.citation: J Appl Physiol (1985). 2001 Jun;90(6):2166-71
references.pmid: 11356779
references.citation: J Strength Cond Res. 2012 Aug;26(8):2293-307
references.pmid: 22002517
references.citation: Int J Behav Med. 1996;3(1):55-69
references.pmid: 16250767
references.citation: Circulation. 2008 Jul 8;118(2):e29-35
references.pmid: 18566319
references.citation: Am J Physiol Endocrinol Metab. 2002 Dec;283(6):E1214-22
references.pmid: 12388173
references.citation: Sports Med. 2000 Jun;29(6):373-86
references.pmid: 10870864
references.citation: Phys Ther. 2008 Feb;88(2):156-75
references.pmid: 18073267
references.citation: Circulation. 2007 Aug 28;116(9):1081-93
references.pmid: 17671237
references.citation: Med Sci Sports Exerc. 1993 Jun;25(6):684-8
references.pmid: 8100607
references.citation: Med Sci Sports Exerc. 2001 Nov;33(11):1811-7
references.pmid: 11689729
references.citation: Med Sci Sports Exerc. 1998 Jan;30(1):11-6
references.pmid: 9475639