title: MRI findings of elevated intracranial pressure in cerebral venous thrombosis versus idiopathic intracranial hypertension with transverse sinus stenosis.
abstract: OBJECTIVE
  To determine whether MRI signs suggesting elevated intracranial pressure (ICP) are preferentially found in patients with idiopathic intracranial hypertension (IIH) than in those with cerebral venous thrombosis (CVT).
  
  
  METHODS
  Among 240 patients who underwent standardized contrast-enhanced brain MRI/MRV at our institution between 9/2009 and 9/2011, 60 with abnormal imaging findings on MRV were included: 27 patients with definite IIH, 2 patients with presumed IIH, and 31 with definite CVT. Medical records were reviewed, and imaging studies were prospectively evaluated by the same neuroradiologist to assess for presence or absence of transverse sinus stenosis (TSS), site of CVT if present, posterior globe flattening, optic nerve sheath dilation/tortuosity, and the size/appearance of the sella turcica.
  
  
  RESULTS
  29 IIH patients (28 women, 19 black, median-age 28, median-body mass index, 34) had bilateral TSS. 31 CVT patients (19 women, 13 black, median-age 46, median-BMI 29) had thrombosis of the sagittal (3), sigmoid (3), cavernous (1), unilateral transverse (7), or multiple (16) sinuses or cortical veins (1). Empty/partially-empty sellae were more common in IIH (3/29 and 24/29) than in CVT patients (1/31 and 19/31) (p<0.001). Flattening of the globes and dilation/tortuosity of the optic nerve sheaths were more common in IIH (20/29 and 18/29) than in CVT patients (13/31 and 5/31) (p<0.04).
  
  
  CONCLUSIONS
  Although abnormal imaging findings suggestive of raised ICP are more common in IIH, they are not specific for IIH and are found in patients with raised ICP from other causes such as CVT.
authors.affiliation: Department of Ophthalmology (MR, BB, BR, LK, NN, VB), Emory University, Atlanta, Georgia, USA.
authors.forename: Maysa A
authors.initials: MA
authors.lastname: Ridha
authors.forename: Amit M
authors.initials: AM
authors.lastname: Saindane
authors.forename: Beau B
authors.initials: BB
authors.lastname: Bruce
authors.forename: Bryan D
authors.initials: BD
authors.lastname: Riggeal
authors.forename: Linda P
authors.initials: LP
authors.lastname: Kelly
authors.forename: Nancy J
authors.initials: NJ
authors.lastname: Newman
authors.forename: Valerie
authors.initials: V
authors.lastname: Biousse
keywords: MRI; MRV; cerebral venous thrombosis; empty sella; idiopathic intracranial hypertension; venous hypertension
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