title: Pd-catalyzed Heck-type cascade reactions with N-tosyl hydrazones: an efficient way to alkenes via in situ generated alkylpalladium.
abstract: A palladium-catalyzed Heck-type cascade reaction of aryl halides and N-tosyl hydrazones is reported. The neopentylpalladium species, generated from an intramolecular Heck-type insertion reaction of aryl halides, could efficiently react with carbenes to form highly functionalized alkenes. The synthesis of spiro compounds was also explored via a multiple Heck-type insertion reaction with N-tosyl hydrazone.
authors.affiliation: Department of Chemistry, University of Science and Technology of China , 96 Jinzhai Road, Hefei, Anhui 230026, People's Republic of China.
authors.forename: Xianglei
authors.initials: X
authors.lastname: Liu
authors.forename: Xinna
authors.initials: X
authors.lastname: Ma
authors.forename: Yunze
authors.initials: Y
authors.lastname: Huang
authors.forename: Zhenhua
authors.initials: Z
authors.lastname: Gu