title: Interplay of hippocampus and prefrontal cortex in memory.
abstract: Recent studies on the hippocampus and the prefrontal cortex have considerably advanced our understanding of the distinct roles of these brain areas in the encoding and retrieval of memories, and of how they interact in the prolonged process by which new memories are consolidated into our permanent storehouse of knowledge. These studies have led to a new model of how the hippocampus forms and replays memories and how the prefrontal cortex engages representations of the meaningful contexts in which related memories occur, as well as how these areas interact during memory retrieval. Furthermore, they have provided new insights into how interactions between the hippocampus and prefrontal cortex support the assimilation of new memories into pre-existing networks of knowledge, called schemas, and how schemas are modified in this process as the foundation of memory consolidation.
authors.affiliation: Center for Learning and Memory, 1 University Station C7000, University of Texas at Austin, Austin, TX 78712-0805, USA.
authors.forename: Alison R
authors.initials: AR
authors.lastname: Preston
authors.forename: Howard
authors.initials: H
authors.lastname: Eichenbaum
mesh_terms: D000818:Animals; D006624:Hippocampus / Q000502:physiology*; D006801:Humans; D008568:Memory / Q000502:physiology*; D017397:Prefrontal Cortex / Q000502:physiology*; D012377:Rodentia / Q000502:physiology
references.citation: Nature. 1999 Feb 18;397(6720):613-6
references.pmid: 10050854
references.citation: Curr Opin Neurobiol. 1995 Apr;5(2):169-77
references.pmid: 7620304
references.citation: J Cogn Neurosci. 1992 Summer;4(3):257-67
references.pmid: 23964882
references.citation: Neuron. 2011 Jul 28;71(2):224-33
references.pmid: 21791282
references.citation: Learn Mem. 2010 Feb 26;17(3):161-7
references.pmid: 20189961
references.citation: Science. 2004 May 7;304(5672):881-3
references.pmid: 15131309
references.citation: J Neurosci. 2009 Aug 5;29(31):9918-29
references.pmid: 19657042
references.citation: Science. 2007 Apr 6;316(5821):76-82
references.pmid: 17412951
references.citation: Science. 2013 Mar 15;339(6125):1290-5
references.pmid: 23493706
references.citation: Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7550-5
references.pmid: 20363957
references.citation: Science. 2004 Jul 2;305(5680):96-9
references.pmid: 15232109
references.citation: Behav Neurosci. 1996 Oct;110(5):887-97
references.pmid: 8918992
references.citation: Trends Cogn Sci. 2011 Aug;15(8):343-51
references.pmid: 21764357
references.citation: J Neurosci. 2007 Apr 25;27(17):4747-55
references.pmid: 17460087
references.citation: Science. 2008 Sep 5;321(5894):1322-7
references.pmid: 18772431
references.citation: Neurosci Biobehav Rev. 2012 May;36(5):1382-99
references.pmid: 22374224
references.citation: Psychol Rev. 1995 Jul;102(3):419-457
references.pmid: 7624455
references.citation: Nature. 2004 Sep 9;431(7005):188-91
references.pmid: 15356631
references.citation: J Neurosci. 2013 Jun 19;33(25):10243-56
references.pmid: 23785140
references.citation: Learn Mem. 2012 Jul 16;19(8):315-8
references.pmid: 22802592
references.citation: Cereb Cortex. 2013 Jan;23(1):80-96
references.pmid: 22275474
references.citation: Trends Cogn Sci. 2013 Feb;17(2):81-8
references.pmid: 23318095
references.citation: Science. 2012 Oct 5;338(6103):135-9
references.pmid: 23042898
references.citation: J Neurosci. 2000 Jun 1;20(11):4320-4
references.pmid: 10818167
references.citation: Curr Opin Neurobiol. 2006 Dec;16(6):693-700
references.pmid: 17097284
references.citation: J Neurosci. 2009 Jun 3;29(22):7208-19
references.pmid: 19494143
references.citation: Neuron. 2002 Aug 29;35(5):989-96
references.pmid: 12372291
references.citation: J Comp Neurol. 1978 Oct 15;181(4):681-715
references.pmid: 690280
references.citation: Nat Rev Neurosci. 2001 Sep;2(9):624-34
references.pmid: 11533730
references.citation: Science. 2011 Aug 12;333(6044):891-5
references.pmid: 21737703
references.citation: J Anat. 2005 Jul;207(1):35-66
references.pmid: 16011544
references.citation: Neuron. 2010 Jun 24;66(6):921-36
references.pmid: 20620877
references.citation: J Neurosci. 2013 Jan 16;33(3):1002-13
references.pmid: 23325238
references.citation: Behav Neurosci. 2003 Oct;117(5):1054-65
references.pmid: 14570554
references.citation: Neuron. 2005 Sep 15;47(6):907-18
references.pmid: 16157284
references.citation: Nature. 1996 Mar 7;380(6569):69-72
references.pmid: 8598908
references.citation: J Neurosci. 2012 Nov 21;32(47):16982-91
references.pmid: 23175849
references.citation: Hippocampus. 2010 Jan;20(1):208-17
references.pmid: 19405137
references.citation: J Int Neuropsychol Soc. 2011 Sep;17(5):766-80
references.pmid: 21729403
references.citation: Trends Cogn Sci. 2013 May;17(5):230-40
references.pmid: 23597720
references.citation: Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):5086-91
references.pmid: 22421138
references.citation: Trends Cogn Sci. 2007 Sep;11(9):379-86
references.pmid: 17707683
references.citation: Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):7109-14
references.pmid: 9192700
references.citation: Annu Rev Neurosci. 2001;24:167-202
references.pmid: 11283309
references.citation: J Neurosci. 2013 May 1;33(18):8079-87
references.pmid: 23637197
references.citation: Neuroscience. 2006 Apr 28;139(1):23-38
references.pmid: 16324795
references.citation: Neuropsychologia. 2009 Sep;47(11):2261-71
references.pmid: 19038275
references.citation: Nat Rev Neurosci. 2007 Nov;8(11):872-83
references.pmid: 17948032
references.citation: Science. 2012 Jun 15;336(6087):1454-8
references.pmid: 22555434
references.citation: Annu Rev Psychol. 2010;61:49-79, C1-4
references.pmid: 19575620
references.citation: Neuron. 2013 Mar 20;77(6):1163-73
references.pmid: 23522050
references.citation: J Neurol Neurosurg Psychiatry. 1957 Feb;20(1):11-21
references.pmid: 13406589
references.citation: Neuron. 2010 May 13;66(3):438-48
references.pmid: 20471356
references.citation: Neuron. 2009 Sep 24;63(6):889-901
references.pmid: 19778516
references.citation: Curr Opin Neurobiol. 2011 Jun;21(3):467-74
references.pmid: 21571522
references.citation: Nat Neurosci. 2007 Jan;10(1):100-7
references.pmid: 17173043
references.citation: Nat Rev Neurosci. 2005 Feb;6(2):119-30
references.pmid: 15685217
references.citation: J Neurosci. 2012 Mar 7;32(10):3453-61
references.pmid: 22399768
references.citation: Curr Biol. 2010 Aug 10;20(15):1336-44
references.pmid: 20637623
references.citation: Curr Opin Neurobiol. 2005 Apr;15(2):219-24
references.pmid: 15831406
references.citation: Neuron. 2005 Apr 7;46(1):141-51
references.pmid: 15820700
references.citation: Neuron. 1998 Mar;20(3):445-68
references.pmid: 9539121
references.citation: Curr Opin Neurobiol. 1997 Apr;7(2):217-27
references.pmid: 9142752
references.citation: Nature. 1996 Jan 18;379(6562):255-7
references.pmid: 8538790
references.citation: J Cogn Neurosci. 2013 Jan;25(1):14-21
references.pmid: 22905817
references.citation: Neuron. 2011 Aug 25;71(4):737-49
references.pmid: 21867888
references.citation: Nat Neurosci. 2009 Jul;12(7):913-8
references.pmid: 19525943
references.citation: J Neurosci. 2009 Jan 28;29(4):930-8
references.pmid: 19176802
references.citation: Science. 2011 Aug 5;333(6043):773-6
references.pmid: 21817056
references.citation: Proc Natl Acad Sci U S A. 2007 May 1;104(18):7723-8
references.pmid: 17449637
references.citation: Nature. 2004 Jan 22;427(6972):352-5
references.pmid: 14737168
references.citation: Neuron. 2012 Jul 12;75(1):168-79
references.pmid: 22794270
references.citation: Trends Neurosci. 2012 Apr;35(4):211-9
references.pmid: 22398180
references.citation: Annu Rev Neurosci. 2007;30:123-52
references.pmid: 17417939
references.citation: J Cogn Neurosci. 1995 Spring;7(2):144-52
references.pmid: 23961820