title: Chemical composition and biological activity of the essential oil from leaves of Moringa oleifera Lam. cultivated in Mozambique.
abstract: The antioxidant capacity and antimicrobial activity of the essential oil of Moringa oleifera (Moringaceae) grown in Mozambique was investigated. The chemical composition was studied by means of GC and GC-MS analysis. Hexacosane (13.9%), pentacosane (13.3%) and heptacosane (11.4%) were the main components. Ultra High Performance Chromatography-DAD analysis detected the flavonoids quercetin (126 μg/g) and luteolin (6.2 μg/g). The essential oil exhibited a relatively low free radical scavenging capacity. The antimicrobial activity of the essential oil was assayed against two Gram-positive strains (Bacillus cereus, Staphylococcus aureus), two Gram-negative strains (Escherichia coli, Pseudomonas aeruginosa), and five fungal strains of agro-food interest (Penicillium aurantiogriseum, Penicillium expansum, Penicillium citrinum, Penicillium digitatum, and Aspergillus niger spp.). B. cereus and P. aeruginosa, as well as the fungal strains were sensitive to the essential oil.
authors.affiliation: Centre for Research and Development in Ethnobotany-CIDE, Rua de Igreja, Casa zero, Vila Namaacha, Maputo Province, Mozambique. tatiana_marrufo@hotmail.com
authors.forename: Tatiana
authors.initials: T
authors.lastname: Marrufo
authors.forename: Filomena
authors.initials: F
authors.lastname: Nazzaro
authors.forename: Emilia
authors.initials: E
authors.lastname: Mancini
authors.forename: Florinda
authors.initials: F
authors.lastname: Fratianni
authors.forename: Raffaele
authors.initials: R
authors.lastname: Coppola
authors.forename: Laura
authors.initials: L
authors.lastname: De Martino
authors.forename: Adelaide Bela
authors.initials: AB
authors.lastname: Agostinho
authors.forename: Vincenzo
authors.initials: V
authors.lastname: De Feo
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001230:Aspergillus / Q000187:drug effects; D001713:Biphenyl Compounds / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005609:Free Radicals / Q000737:chemistry; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D057927:Hydrophobic and Hydrophilic Interactions; D047311:Luteolin; D008826:Microbial Sensitivity Tests; D029588:Moringa oleifera / Q000737:chemistry*; D009073:Mozambique; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010407:Penicillium / Q000187:drug effects; D010851:Picrates / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D011794:Quercetin
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005609:Free Radicals; D009822:Oils, Volatile; D010851:Picrates; D010938:Plant Oils; D011794:Quercetin; C004931:1,1-diphenyl-2-picrylhydrazyl; D047311:Luteolin
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