title: Perceptions, knowledge, and satisfaction with contralateral prophylactic mastectomy among young women with breast cancer: a cross-sectional survey.
abstract: Chinese translation
  
  
  BACKGROUND
  Rates of contralateral prophylactic mastectomy (CPM) have increased dramatically, particularly among younger women with breast cancer, but little is known about how women approach the decision to have CPM.
  
  
  OBJECTIVE
  To examine preferences, knowledge, decision making, and experiences of young women with breast cancer who choose CPM.
  
  
  METHODS
  Cross-sectional survey.
  
  
  METHODS
  8 academic and community medical centers that enrolled 550 women diagnosed with breast cancer at age 40 years or younger between November 2006 and November 2010.
  
  
  METHODS
  123 women without known bilateral breast cancer who reported having bilateral mastectomy.
  
  
  METHODS
  A 1-time, 23-item survey that included items related to decision making, knowledge, risk perception, and breast cancer worry.
  
  
  RESULTS
  Most women indicated that desires to decrease their risk for contralateral breast cancer (98%) and improve survival (94%) were extremely or very important factors in their decision to have CPM. However, only 18% indicated that women with breast cancer who undergo CPM live longer than those who do not. BRCA1 or BRCA2 mutation carriers more accurately perceived their risk for contralateral breast cancer, whereas women without a known mutation substantially overestimated this risk.
  
  
  CONCLUSIONS
  The survey, which was administered a median of 2 years after surgery, was not validated, and some questions might have been misinterpreted by respondents or subject to recall bias. Generalizability of the findings might be limited.
  
  
  CONCLUSIONS
  Despite knowing that CPM does not clearly improve survival, women who have the procedure do so, in part, to extend their lives. Many women overestimate their actual risk for cancer in the unaffected breast. Interventions aimed at improving risk communication in an effort to promote evidence-based decision making are warranted.
  
  
  BACKGROUND
  Susan G. Komen for the Cure.
authors.forename: Shoshana M
authors.initials: SM
authors.lastname: Rosenberg
authors.forename: Michaela S
authors.initials: MS
authors.lastname: Tracy
authors.forename: Meghan E
authors.initials: ME
authors.lastname: Meyer
authors.forename: Karen
authors.initials: K
authors.lastname: Sepucha
authors.forename: Shari
authors.initials: S
authors.lastname: Gelber
authors.forename: Judi
authors.initials: J
authors.lastname: Hirshfield-Bartek
authors.forename: Susan
authors.initials: S
authors.lastname: Troyan
authors.forename: Monica
authors.initials: M
authors.lastname: Morrow
authors.forename: Lidia
authors.initials: L
authors.lastname: Schapira
authors.forename: Steven E
authors.initials: SE
authors.lastname: Come
authors.forename: Eric P
authors.initials: EP
authors.lastname: Winer
authors.forename: Ann H
authors.initials: AH
authors.lastname: Partridge
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000235:genetics / Q000601:surgery*; D003430:Cross-Sectional Studies; D003657:Decision Making; D005260:Female; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008408:Mastectomy / Q000379:methods* / Q000523:psychology; D009154:Mutation; D017060:Patient Satisfaction; D010465:Perception; D011446:Prospective Studies; D012307:Risk Factors; D011795:Surveys and Questionnaires
references.citation: J Clin Oncol. 2007 Jan 20;25(3):285-91
references.pmid: 17159191
references.citation: Breast Dis. 2005-2006;23:103-13
references.pmid: 16823173
references.citation: J Clin Oncol. 2005 Nov 1;23(31):7849-56
references.pmid: 16204003
references.citation: Ann Surg Oncol. 2010 Oct;17(10):2702-9
references.pmid: 20853163
references.citation: J Clin Oncol. 2009 Feb 20;27(6):974-85
references.pmid: 19124808
references.citation: Ann Surg Oncol. 2012 Aug;19(8):2600-6
references.pmid: 22396004
references.citation: Cancer Prev Res (Phila). 2010 Aug;3(8):1026-34
references.pmid: 20647335
references.citation: J Clin Oncol. 2007 Nov 20;25(33):5203-9
references.pmid: 17954711
references.citation: Br J Cancer. 2005 Aug 8;93(3):287-92
references.pmid: 16052221
references.citation: Ann Surg Oncol. 2009 Oct;16(10):2697-704
references.pmid: 19653045
references.citation: J Clin Oncol. 2011 Apr 20;29(12):1564-9
references.pmid: 21402610
references.citation: N Engl J Med. 1986 Aug 28;315(9):559-63
references.pmid: 3736639
references.citation: Ann Surg Oncol. 2011 Oct;18(11):3129-36
references.pmid: 21947590
references.citation: J Clin Oncol. 2005 Aug 20;23(24):5526-33
references.pmid: 16110013
references.citation: Br J Cancer. 2009 Feb 24;100(4):583-9
references.pmid: 19209174
references.citation: Ann Surg Oncol. 1999 Sep;6(6):546-52
references.pmid: 10493622
references.citation: Med Decis Making. 1995 Jan-Mar;15(1):25-30
references.pmid: 7898294
references.citation: Ann Surg Oncol. 2010 Oct;17 Suppl 3:330-7
references.pmid: 20853055
references.citation: J Natl Cancer Inst. 2009 Oct 7;101(19):1337-47
references.pmid: 19720966
references.citation: Lancet Oncol. 2013 Jun;14(7):e262-9
references.pmid: 23725708
references.citation: Cancer. 1999 Nov 1;86(9):1768-74
references.pmid: 10547550
references.citation: Eur J Cancer. 2012 Nov;48(17):3150-6
references.pmid: 22695071
references.citation: Ann Surg Oncol. 2011 Oct;18(11):3110-6
references.pmid: 21947589
references.citation: J Clin Oncol. 2013 Feb 1;31(4):433-9
references.pmid: 23269995
references.citation: J Natl Cancer Inst. 2012 Mar 7;104(5):386-405
references.pmid: 22271773
references.citation: J Natl Cancer Inst. 2008 Feb 20;100(4):243-51
references.pmid: 18270338
references.citation: Breast J. 2011 Jan-Feb;17(1):18-23
references.pmid: 21155919
references.citation: BMC Med Inform Decis Mak. 2012 Jun 08;12:51
references.pmid: 22681763
references.citation: Ann Surg Oncol. 2010 Oct;17(10):2554-62
references.pmid: 20461470
references.citation: JAMA. 2010 Sep 1;304(9):967-75
references.pmid: 20810374
references.citation: J Clin Oncol. 2007 Mar 20;25(9):1067-73
references.pmid: 17369570
references.citation: Oncologist. 2011;16(7):935-41
references.pmid: 21672945
references.citation: Breast Cancer Res Treat. 2010 Dec;124(3):835-44
references.pmid: 20446031
references.citation: Breast Cancer Res Treat. 2007 Sep;104(3):321-9
references.pmid: 17066320
references.citation: J Clin Oncol. 2004 May 15;22(10):1849-56
references.pmid: 15143077
references.citation: Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):675-80
references.pmid: 20160274
references.citation: Breast Cancer Res. 2012 May 23;14(3):R82
references.pmid: 22621306
references.citation: J Clin Oncol. 2011 Jun 1;29(16):2158-64
references.pmid: 21464413
references.citation: J Clin Oncol. 2012 Nov 10;30(32):3960-6
references.pmid: 23032615
references.citation: Ann Surg Oncol. 2009 Oct;16(10):2691-6
references.pmid: 19506956
references.citation: JAMA. 2004 Jul 28;292(4):435-41
references.pmid: 15280341
references.citation: Patient Educ Couns. 2012 Feb;86(2):195-204
references.pmid: 21665420
references.citation: J Clin Oncol. 2006 Mar 20;24(9):1350-6
references.pmid: 16549829
references.citation: J Natl Cancer Inst. 1995 Feb 15;87(4):286-92
references.pmid: 7707420
references.citation: J Clin Oncol. 2008 Mar 1;26(7):1093-7
references.pmid: 18195327
references.citation: Can Fam Physician. 2010 Aug;56(8):e308-14
references.pmid: 20705870
references.citation: J Clin Oncol. 2009 Mar 20;27(9):1362-7
references.pmid: 19224844
references.citation: J Natl Cancer Inst Monogr. 2005;(35):55-60
references.pmid: 16287886
references.citation: Qual Life Res. 2005 Aug;14(6):1467-79
references.pmid: 16110927
references.citation: Cancer Epidemiol Biomarkers Prev. 2012 Jul;21(7):1066-77
references.pmid: 22556274