Isoflavones and soyasaponins in soy infant formulas in Brazil: profile and estimated consumption.
In the present study we determine the contents of isoflavones and soyasaponins in seven soy-based infant formulas available in the Brazilian market to estimate the intake of these bioactive compounds by infants. The mean contents of isoflavones and soyasaponins were 65.9mg/kg and 55.0mg/100g, respectively. β-Glycosylated isoflavones and soyasaponin B-I were the most abundant components in the analysed samples. The mean estimated intake of isoflavones by infants fed soy-based formulas was 0.8mg/day/kg of body weight, which is twice that of Japanese adults. For soyasaponins, the mean estimated intake was 9.2mg/day/kg of body weight, which is up to 6 times higher than the daily intake of saponins from beans by vegetarians. Considering the estimated intake of these bioactive compounds from soy-based formulas and the paucity of data regarding their bioavailability, the potential biological effects of isoflavones and soyasaponins in infants should not be overlooked and merits further investigation.
Laboratório de Bioquímica Nutricional e de Alimentos, Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Av. Athos da Silveira Ramos 149, CT, Bloco A, sala 528A, 21941-909 Rio de Janeiro, Brazil. Electronic address: niveadiasdafonseca@gmail.com.
Nívea D
ND
Fonseca
Marcos Paulo Melo
MP
Villar
Carmen Marino
CM
Donangelo
Daniel
D
Perrone
D001938:Brazil; D004435:Eating; D006801:Humans; D007223:Infant; D041943:Infant Formula / Q000737:chemistry* / Q000378:metabolism*; D007529:Isoflavones / Q000032:analysis* / Q000378:metabolism; D064167:Recommended Dietary Allowances; D012503:Saponins / Q000032:analysis* / Q000378:metabolism; D013025:Glycine max / Q000737:chemistry* / Q000378:metabolism
D007529:Isoflavones; D012503:Saponins
Infant formulas; Isoflavones; LC–MS; Saponins; Soy