Definition of stereotactic body radiotherapy: principles and practice for the treatment of stage I non-small cell lung cancer.
This report from the Stereotactic Radiotherapy Working Group of the German Society of Radiation Oncology (Deutschen Gesellschaft für Radioonkologie, DEGRO) provides a definition of stereotactic body radiotherapy (SBRT) that agrees with that of other international societies. SBRT is defined as a method of external beam radiotherapy (EBRT) that accurately delivers a high irradiation dose to an extracranial target in one or few treatment fractions. Detailed recommendations concerning the principles and practice of SBRT for early stage non-small cell lung cancer (NSCLC) are given. These cover the entire treatment process; from patient selection, staging, treatment planning and delivery to follow-up. SBRT was identified as the method of choice when compared to best supportive care (BSC), conventionally fractionated radiotherapy and radiofrequency ablation. Based on current evidence, SBRT appears to be on a par with sublobar resection and is an effective treatment option in operable patients who refuse lobectomy.
Department of Radiation Oncology, University of Würzburg, Josef-Schneider-Str. 11, 97080, Würzburg, Germany, guckenberger_m@klinik.uni-wuerzburg.de.
M
M
Guckenberger
N
N
Andratschke
H
H
Alheit
R
R
Holy
C
C
Moustakis
U
U
Nestle
O
O
Sauer
D002289:Carcinoma, Non-Small-Cell Lung / Q000532:radiotherapy*; D005858:Germany; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy*; D018787:Radiation Oncology / Q000592:standards*; D016634:Radiosurgery / Q000592:standards*; D011880:Radiotherapy Planning, Computer-Assisted / Q000592:standards*