Association between physical activity measurements and key parameters of cardiopulmonary exercise testing in patients with heart failure.
BACKGROUND
A hallmark characteristic of heart failure (HF) is reduced physical activity (PA) patterns. The relationship between key cardiopulmonary exercise testing (CPX) variables and PA patterns has not been investigated. Therefore, we evaluated PA patterns in patients with ischemic HF and its relationship to peak oxygen consumption (VO2), the minute ventilation/carbon dioxide production (VE/VCO2) slope, and the oxygen uptake efficiency slope (OUES).


RESULTS
Sixteen patients with HF wore an accelerometer for six days to measure total steps/day as well as percentage of time at light, moderate, and vigorous PA. Symptom-limited CPX was performed on a treadmill using a ramping protocol. Total steps correlated with VO2 (r = 0.64 P < .05), the VE/VCO2 slope (r = -0.72; P < .05), and the OUES (0.63; P < .05). The percentage of time at light-intensity PA correlated with the VE/VCO2 slope (r = 0.58; P < .05) and the OUES (r = -0.51; P < .05). The percentage of time at vigorous-intensity PA correlated with peak VO2 (r = 0.55; P < .05) and the VE/VCO2 slope (r = -0.52; P < .05).


CONCLUSIONS
PA assessed by accelerometer is significantly associated with key CPX variables in patients with HF.
Division of Physical Therapy, Ceilandia College, University of Brasilia, Brasilia, Brazil; Ergometry and Sports Medicine Department, Heart Institute of Distrito Federal, Brasília, Brazil. Electronic address: viniciusmaldaner@gmail.com.
Vinicius Z M
VZ
da Silva
Alexandra C
AC
Lima
Fillippe T
FT
Vargas
Lawrence P
LP
Cahalin
Ross
R
Arena
Gerson
G
Cipriano
D000368:Aged; D003430:Cross-Sectional Studies; D016208:Databases, Factual; D005080:Exercise Test / Q000379:methods*; D006333:Heart Failure / Q000175:diagnosis* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D010101:Oxygen Consumption / Q000502:physiology
Heart failure; exercise test; physical activity