Waist circumference in predicting gestational diabetes mellitus.
BACKGROUND
To evaluate waist circumference (WC) measured at 20-24 weeks of gestation as a predictor of gestational diabetes mellitus (GDM).


METHODS
This cross-sectional study included 240 women at 20-24 weeks of gestation. At enrollment, WC was measured, and both prepregnancy and gestational body mass index (BMI) were estimated. According to the results of 75-g oral glucose tolerance test (OGTT) performed at 24-28 weeks, subjects were allocated into two groups, non-GDM and GDM. WC sensitivity and specificity, and odds ratios (OR) and 95% confidence intervals for BMI and WC were estimated, and a receiver operating characteristics curve was generated.


RESULTS
Of the 240 pregnant women enrolled, 31 (13%) had GDM. Prepregnancy BMI (OR = 4.21), gestational BMI (OR = 3.17) and WC at 20-24 weeks (OR = 4.02) correlated with GDM risk. At 20-24 weeks, a WC of 85.5-88.5 cm was the optimal cutoff point for predicting GDM (Sens/Spec balance between 87.1/41.1% and 77.4/56.9%).


CONCLUSIONS
At 20-24 weeks of gestation, WC values in the range of 86-88 cm showed to be a good performance in predicting GDM.
Escola Superior de Ciências da Saúde , FEPECS, Brasília - DF , Brasil and.
Cláudia Vicari
CV
Bolognani
Lilian Barros
LB
de Sousa Moreira Reis
Sulani Silva
SS
de Souza
Adriano
A
Dias
Marilza Vieira Cunha
MV
Rudge
Iracema
I
de Mattos Paranhos Calderon
D015992:Body Mass Index; D003430:Cross-Sectional Studies; D016640:Diabetes, Gestational / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011379:Prognosis; D012307:Risk Factors; D012680:Sensitivity and Specificity; D055105:Waist Circumference / Q000502:physiology*
Gestational diabetes mellitus; risk factor; waist circumference