Pressure accelerated 1,3-dipolar cycloaddition of azide and alkyne groups in crystals.
The cycloaddition of azides and alkynes in the solid state was accelerated by high pressure. In situ Raman scattering and synchrotron X-ray diffraction were employed to study reaction kinetics at different pressures which revealed that the pressure acceleration originates from the elevated substrate energy and decreased activation energy.
Beijing National Laboratory for Molecular Sciences (BNLMS), Key Lab of Polymer Chemistry & Physics of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China. ygma@pku.edu.cn.
Ben-Bo
BB
Ni
Kai
K
Wang
Qifan
Q
Yan
Hao
H
Chen
Yuguo
Y
Ma
Bo
B
Zou