Alcohol use and death from respiratory disease in a prospective Chinese elderly cohort study in Hong Kong.
OBJECTIVE
In Western settings, moderate drinking is negatively associated with respiratory disease. However, moderate drinking is socially patterned, making this association vulnerable to contextual biases. Evidence from other contexts where the typical drinking pattern is different may clarify such observations.


METHODS
Multivariable Cox regression analysis was used to assess the adjusted associations of alcohol use with death from respiratory disease using a population-based prospective cohort of 66,820 Chinese aged ≥65 years enrolled from July 1998 to December 2001 at all the 18 Elderly Health Centers of the Hong Kong Government Department of Health and followed till May 30, 2012.


RESULTS
During ten-year follow-up, 4065 deaths from respiratory disease occurred. Most current drinkers were occasional drinkers (<1 day/week). Both moderate and occasional drinking (<1 day/week) were associated with a lower risk of death from respiratory disease, but the point estimates and pattern of associations were similar between these two types of drinkers.


CONCLUSIONS
The typical drinking pattern, i.e. occasional drinking (<1 day/week), which is unlikely to have any biological effect, was similarly associated with a lower risk of respiratory disease as moderate alcohol use, suggesting the attributes of being a typical drinker may be protective.
Life Course and Lifestyle Epidemiology Group, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Chen
C
Shen
Michael Yuxuan
MY
Ni
C Mary
CM
Schooling
Wai Man
WM
Chan
Siu Yin
SY
Lee
Tai Hing
TH
Lam
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000009:adverse effects* / Q000453:epidemiology; D005260:Female; D006304:Health Status; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D008297:Male; D011014:Pneumonia / Q000209:etiology / Q000401:mortality; D016016:Proportional Hazards Models; D011446:Prospective Studies; D029424:Pulmonary Disease, Chronic Obstructive / Q000209:etiology / Q000401:mortality; D012141:Respiratory Tract Infections / Q000209:etiology / Q000401:mortality*; D012307:Risk Factors; D012959:Socioeconomic Factors
Alcohol; BMI; CI; COPD; HR; ICD; International Classification of Disease; Mortality; Respiratory disease; body mass index; chronic obstructive pulmonary disease; confidence interval; hazard ratio