In vitro activity of temocillin against multidrug-resistant clinical isolates of Escherichia coli, Klebsiella spp. and Enterobacter spp., and evaluation of high-level temocillin resistance as a diagnostic marker for OXA-48 carbapenemase.
Antimicrobial Resistance and Healthcare Associated Infections (AMRHAI) Reference Unit, Public Health England, London NW9 5EQ, UK.
Neil
N
Woodford
Rachel
R
Pike
Daniele
D
Meunier
Richard
R
Loy
Robert
R
Hill
Katie L
KL
Hopkins
D001426:Bacterial Proteins / Q000302:isolation & purification; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects* / Q000502:physiology; D004754:Enterobacter / Q000187:drug effects* / Q000302:isolation & purification; D004926:Escherichia coli / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D007709:Klebsiella / Q000187:drug effects* / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests / Q000379:methods; D010406:Penicillins / Q000494:pharmacology*; D001618:beta-Lactamases / Q000302:isolation & purification
D001426:Bacterial Proteins; D010406:Penicillins; C031367:temocillin; D001618:beta-Lactamases; C063912:carbapenemase; C108449:oxacillinase
ESBLs; Enterobacteriaceae; KPC; NDM; VIM