Evidence for cytomegalovirus-induced haemophagocytic syndrome in a young patient with AIDS.
A 29-year-old man with HIV infection was referred to our department because of a 1-month history of low-grade fever and fatigue. Bone marrow aspiration and biopsy showed findings consistent with haemophagocytic syndrome (HPS), and immunohistochemical assessment showed cytomegalovirus (CMV) infection. HIV-associated HPS can occur at any stages of HIV disease and requires diverse differential diagnosis. CMV-associated HPS (CMV-HPS) in patients with HIV infection is relatively rare, but the present case showed that the clinicians should consider the possibility of CMV-HPS as a clinical feature of CMV infection.
Department of Respiratory Medicine, Kyorin University School of Medicine, Mitaka, Japan.
Kosuke
K
Ohkuma
Takeshi
T
Saraya
Mitsuru
M
Sada
Shin
S
Kawai
D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D001706:Biopsy; D003587:Cytomegalovirus; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D014057:Tomography, X-Ray Computed