Follicular variant of papillary carcinoma presenting as a hyperfunctioning thyroid nodule.
In this study, we describe a case of papillary carcinoma in a 15-year-old girl who presented with a hyperfunctioning (hot) thyroid nodule and discuss it in the context of current management guidelines for patients with thyroid nodules. In adults, hot nodules rarely require cytologic or histologic evaluation, and hyperthyroidism is often treated with radioiodine (131I). However, in children and adolescents, the malignancy rate for nodules (both cold and hot) is higher and surgery is often necessary. Surgery may serve as a therapy, as well as a diagnostic tool, to treat hot nodules in children and adolescents.
Departments of *Internal Medicine IV †Pediatrics ‡The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital in Hradec Kralove, Hradec Králové, Czech Republic.
Filip
F
Gabalec
Ioannis
I
Svilias
Ivana
I
Plasilova
Eva
E
Hovorkova
Aler
A
Ryska
Jiri
J
Horacek
D000293:Adolescent; D018265:Carcinoma, Papillary, Follicular / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000601:surgery; D016606:Thyroid Nodule / Q000175:diagnosis*; D013965:Thyroidectomy