Three-component Synthesis of Novel Highly Functionalized 2,6-dihydropyrimido[2,1-a]isoindole Derivatives.
Three-component reaction of dialkyl acetylenedicarboxylates, isocyanides and 1,3- diimino isoindoline affords highly functionalized 2,6-dihydropyrimido[2,1-a]isoindole derivatives in good yields under catalyst free and mild reaction conditions.
Robabeh
R
Baharfar
Najmeh
N
Abbasi