Cherubism: panoramic and CT features in adults.
OBJECTIVE
To describe the panoramic radiographic and CT features of cherubism in an unselected series of 15 adults.


METHODS
In this cross-sectional study, 15 individuals aged 29-84 years with familial non-syndromal molecularly confirmed cherubism were examined with panoramic radiography and CT. Bone abnormalities were analysed and described.


RESULTS
11 (73%) of the 15 adults had mandibular abnormalities. These abnormalities ranged from subtly detectable to severe, and were less prevalent and expansive but could be rather similar to the characteristic image features in children. Unilocular radiolucencies were more common than multilocular radiolucencies, and a specific feature of these abnormalities was that they were exclusively found in the anterior mandible.


CONCLUSIONS
The radiographic and CT abnormalities of cherubism in adults were frequent and extremely heterogeneous, with some distinct features.
Department of Maxillofacial Radiology, Faculty of Dentistry, University of Oslo, Blindern, Oslo, Norway;
M
M
Redfors
J L
JL
Jensen
K
K
Storhaug
T
T
Prescott
T A
TA
Larheim
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000539:Alveolar Process / Q000000981:diagnostic imaging; D002636:Cherubism / Q000000981:diagnostic imaging*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000000981:diagnostic imaging; D008439:Maxillary Diseases / Q000000981:diagnostic imaging; D008443:Maxillary Sinus / Q000000981:diagnostic imaging; D008875:Middle Aged; D010159:Palate / Q000000981:diagnostic imaging; D011862:Radiography, Panoramic / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*
cherubism; computed tomography; genetics; radiology