New way of direct nitrogen atom phenylation in quinoline derivatives.
Comparison of ion-molecular reactions of free-phenyl cations generated by tritium β -decay with 2-methyl- and 2-phenylquinolines has been investigated. The reaction of direct nitrogen atom phenylation with the help of nucleogenic phenyl cations has been fulfilled for the first time and a new one-step synthesis of tritium-labeled N-phenyl-2-phenylquinolinium salt-lipophilic radioactive biological marker has been elaborated.
Laboratory of Radiochemistry, Natural Sciences Institute, Perm State University, Perm 614990, Russia.
Nadezhda E
NE
Shchepina
Viktor V
VV
Avrorin
Gennady A
GA
Badun
Scott B
SB
Lewis
Sergey N
SN
Shurov