Evaluation of linear accelerator-based stereotactic radiosurgery in the management of meningiomas: a single center experience.
OBJECTIVE
Stereotactic radiosurgery (SRS) has emerged as a viable alternative to surgery in the management of meningioma through exploiting the advantage of being minimally invasive with few complications and acceptable local control rates. The aim of this study was to evaluate the efficiency of linear accelerator (LINAC)-based SRS in the management of meningiomas and to report our experience using this sophisticated technique.


METHODS
Between July 1998 and March 2012, 79 patients (42 female, 37 male) were treated using LINAC-based SRS in the Department of Radiation Oncology, Gulhane Military Medical Academy. Median dose was 13 Gy (range 10- 16) prescribed to the 80-95% isodose line encompassing the target.


RESULTS
Median follow-up time was 53 months (range 9-112). Median tumor volume was 3.43 cc (range 0.3-14.1). Local tumor control was 89.7% in the 68 patients with adequate follow-up.


CONCLUSIONS
LINAC-based SRS offers a safe and effective treatment alternative to surgery in intracranial meningiomas with high local control rates and low morbidity.
Department of Radiation Oncology, Gulhane Military Medical Academy, Ankara, Turkey.
F
F
Dincoglan
M
M
Beyzadeoglu
O
O
Sager
B
B
Uysal
S
S
Demiral
H
H
Gamsiz
B
B
Dirican
D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000601:surgery*; D008579:Meningioma / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D060787:Neoplasm Grading; D011379:Prognosis; D016634:Radiosurgery; D014057:Tomography, X-Ray Computed