Auditory neuroimaging with fMRI and PET.
For much of the past 30 years, investigations of auditory perception and language have been enhanced or even driven by the use of functional neuroimaging techniques that specialize in localization of central responses. Beginning with investigations using positron emission tomography (PET) and gradually shifting primarily to usage of functional magnetic resonance imaging (fMRI), auditory neuroimaging has greatly advanced our understanding of the organization and response properties of brain regions critical to the perception of and communication with the acoustic world in which we live. As the complexity of the questions being addressed has increased, the techniques, experiments and analyses applied have also become more nuanced and specialized. A brief review of the history of these investigations sets the stage for an overview and analysis of how these neuroimaging modalities are becoming ever more effective tools for understanding the auditory brain. We conclude with a brief discussion of open methodological issues as well as potential clinical applications for auditory neuroimaging. This article is part of a Special Issue entitled Human Auditory Neuroimaging.
School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN, USA; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA. Electronic address: tmt@purdue.edu.
Thomas M
TM
Talavage
Javier
J
Gonzalez-Castillo
Sophie K
SK
Scott
D000818:Animals; D001303:Auditory Cortex / Q000033:anatomy & histology / Q000098:blood supply / Q000000981:diagnostic imaging / Q000502:physiology*; D001306:Auditory Pathways / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology; D001307:Auditory Perception; D001931:Brain Mapping / Q000379:methods*; D002560:Cerebrovascular Circulation; D006439:Hemodynamics; D006801:Humans; D008279:Magnetic Resonance Imaging; D049268:Positron-Emission Tomography