Decrease in the incidence of culture-positive meningitis and cerebral tuberculomas in France from 1990 to 2007.
We evaluated the incidence rate of culture-positive central nervous system tuberculosis (CNS TB) in France in 2007 and its time trend between 1990 and 2007. We used a capture-recapture analysis by using data recorded in 2007 by the mandatory notification system and the national network of the National Reference Centre (NRC). The 2007 sensitivity of the NRC was 79·4%. The previous sensitivity for 2000 (75·6%) and that for 2007 yielded a pooled estimate of 77·4% (95% confidence interval 64·8-88·0), which was used to extrapolate the number of culture-positive CNS TB cases from those reported in four surveys (1990, 1995, 2000, 2007). The extrapolated number of culture-positive CNS TB cases fell from 90 to 35 between 1990 and 2007, and the extrapolated incidence rates fell from 1·6 to 0·55 cases/million (P < 0·001). This favourable trend should be closely monitored following the change of the BCG vaccination policy in 2007.
EA 1541/ER5, Faculté de Médecine Pierre et Marie Curie-Paris 6, Site Pitié,UPMC,Paris,France.
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Bui
EA 1541/ER5, Faculté de Médecine Pierre et Marie Curie-Paris 6, Site Pitié,UPMC,Paris,France.
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Meyssonnier
UMR S 707, Faculté de Médecine Pierre et Marie Curie-Paris 6,UPMC,Paris,France.
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Boelle
Département des Maladies Infectieuses,Institut de Veille Sanitaire (InVS),Saint-Maurice,France.
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Che
Département des Maladies Infectieuses,Institut de Veille Sanitaire (InVS),Saint-Maurice,France.
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Antoine
EA 1541/ER5, Faculté de Médecine Pierre et Marie Curie-Paris 6, Site Pitié,UPMC,Paris,France.
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Jarlier
EA 1541/ER5, Faculté de Médecine Pierre et Marie Curie-Paris 6, Site Pitié,UPMC,Paris,France.
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Robert
D000328:Adult; D001500:BCG Vaccine / Q000008:administration & dosage; D001927:Brain Diseases / Q000453:epidemiology* / Q000382:microbiology; D018563:Disease Notification; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008581:Meningitis / Q000453:epidemiology* / Q000382:microbiology; D008875:Middle Aged; D012189:Retrospective Studies; D016862:Tuberculoma, Intracranial / Q000453:epidemiology* / Q000382:microbiology; D055815:Young Adult
D001500:BCG Vaccine