Food intake and the risk of endometrial endometrioid adenocarcinoma in Japanese women.
The present study examined the association between food intake and endometrial cancer restricted to endometrial endometrioid adenocarcinoma (EEA) using a case-control study in Japanese women. One hundred sixty-one cases and 380 controls who completed a questionnaire regarding demographic, lifestyle, and food frequency questionnaire were analyzed. Odds ratio (OR) between selected food intakes and EEA were calculated by logistic regression analysis. After adjustment putative confounding factors, the higher intakes of vegetables [odds ratio (OR) = 0.47, 95% confidence interval (CI) = 0.26-0.83], peanuts (OR = 0.48, CI = 0.27-0.86), fish (OR = 0.52, CI = 0.29-0.93), boiled egg (OR = 0.24, CI = 0.33-0.92), instant noodles (OR = 1.94, CI = 1.12-3.34), instant food items (OR = 2.21, CI = 1.31-3.74), and deep-fried foods (OR = 2.87, CI = 1.58-5.21) were associated with a risk for EEA. The inverse association with a risk of EEA was also seen in higher intakes (g/1000 kcal) for vegetables (0.45, CI = 0.25-0.81) and fish (0.53, CI = 0.30-0.94) as compare to lower intake. Higher intake of vegetables, peanuts, fish, and boiled egg was associated with a reduced risk for EEA, whereas instant noodles, instant food items, and deep-fried foods was associated with an increased risk for EAA as compared to lower levels of intake.
a Comprehensive Education Center for Community Medicine , Tohoku University Graduate School of Medicine , Sendai , Japan.
Shin
S
Takayama
Yasutake
Y
Monma
Megumi
M
Tsubota-Utsugi
Satoru
S
Nagase
Yoshitaka
Y
Tsubono
Takehiro
T
Numata
Masafumi
M
Toyoshima
Hiroki
H
Utsunomiya
Junichi
J
Sugawara
Nobuo
N
Yaegashi
D000328:Adult; D000368:Aged; D000818:Animals; D010367:Arachis; D044466:Asian People; D018269:Carcinoma, Endometrioid / Q000517:prevention & control*; D016022:Case-Control Studies; D016001:Confidence Intervals; D004531:Eggs; D016889:Endometrial Neoplasms / Q000517:prevention & control*; D005247:Feeding Behavior; D005260:Female; D005399:Fishes; D005638:Fruit; D006801:Humans; D007564:Japan; D008019:Life Style; D016015:Logistic Models; D008460:Meat; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014675:Vegetables