Comment on "Community-wide isoniazid preventive therapy drives drug-resistant tuberculosis: a model-based analysis".
Mills et al. recently used mathematical modeling to show that community-wide isoniazid preventative therapy may lead to a long-term increase in resistance at the population level. Although community-wide isoniazid preventive therapy may be useful in preventing tuberculosis (TB) in low-TB/HIV settings, isoniazid resistance is especially of concern in high TB/HIV populations.
Department of Internal Medicine, Federal Teaching Hospital, P. O. Box 06, Abakaliki, Ebonyi State 480281, Nigeria.
Kingsley N
KN
Ukwaja
D000995:Antitubercular Agents / Q000627:therapeutic use*; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D014376:Tuberculosis / Q000188:drug therapy*
D000995:Antitubercular Agents; D007538:Isoniazid