A traceless Staudinger reagent to deliver diazirines.
A triarylphosphine reagent that reacts with organic azides to install amide-linked diazirines is reported. This traceless Staudinger reagent reacts with complex organic azides to yield amide-linked diazirines, thus expanding the scope of the utility of both azide and diazirine chemistry.
University of Arizona , 1306 East University Boulevard, Tucson, Arizona 85721, United States.
Ali M
AM
Ahad
Stephanie M
SM
Jensen
John C
JC
Jewett
D001386:Azides / Q000737:chemistry*; D003978:Diazomethane / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry*; D015394:Molecular Structure; D010720:Phosphines / Q000737:chemistry*
D001386:Azides; D007202:Indicators and Reagents; D010720:Phosphines; D003978:Diazomethane