A mild, selective copper-catalyzed oxidative phosphonation of α-amino ketones.
A novel and selective method of simple copper-salt catalyzed phosphonation of α-amino carbonyl compounds to afford imidoylphosphonates is reported. This reaction system has a broad reaction scope. The convenient and environmentally benign process makes this protocol very attractive.
State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou 730000, P. R. China, and State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics , Lanzhou 730000, P. R. China.
Bin
B
Yang
Ting-Ting
TT
Yang
Xi-An
XA
Li
Jun-Jiao
JJ
Wang
Shang-Dong
SD
Yang
D002384:Catalysis; D003300:Copper; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D007659:Ketones; D009943:Organophosphorus Compounds; D003300:Copper