Light-controlled ion channels formed by amphiphilic small molecules regulate ion conduction via cis-trans photoisomerization.
Light-regulated ion channel-transport across lipid bilayers was realized using structurally simple azobenzene-based amphiphilic small molecules. UV or visible irradiation triggers molecular photoisomerization, which induces structural and membrane affinity changes in self-assembled channels, thus resulting in light-regulated ion transmembrane transport.
Shanghai Key Laboratory of Functional Materials Chemistry, Institute of Fine Chemicals, East China University of Science and Technology, 130# Meilong Road, Shanghai, 200237, P. R. China. baochunyan@ecust.edu.cn linyongzhu@ecust.edu.cn.
Tao
T
Liu
Chunyan
C
Bao
Haiyan
H
Wang
Yao
Y
Lin
Huijuan
H
Jia
Linyong
L
Zhu
D001391:Azo Compounds / Q000737:chemistry*; D004553:Electric Conductivity; D004579:Electron Transport; D007473:Ion Channels / Q000737:chemistry*; D008027:Light; D008051:Lipid Bilayers / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D055668:Photochemical Processes; D013237:Stereoisomerism; D013501:Surface-Active Agents / Q000737:chemistry*; D014466:Ultraviolet Rays
D001391:Azo Compounds; D007473:Ion Channels; D008051:Lipid Bilayers; D013501:Surface-Active Agents; C009850:azobenzene