Mortality among HIV/AIDS patients coinfected with Mycobacterium tuberculosis in southern Thailand.
The purpose of this study was to investigate the mortality rate among HIV/AIDS patients coinfected with Mycobacterium tuberculosis in southern Thailand. A prospective, hospital-based cohort study was conducted among 52,459 HIV/AIDS patients registered at hospitals in 14 provinces of southern Thailand between January 1990 and April 2010. Twenty-seven point nine percent of the subjects were coinfected with Mycobacterium tuberculosis. Coinfection with Mycobacterium tuberculosis was not significantly associated with an increased mortality among subjects (HR 1.01; 95%CI 0.96-1.05). Subjects with pulmonary tuberculosis infection were 19% more likely to have a longer life (HR 0.81, 95%CI 0.73-0.91) and subjects with extrapulmonary tuberculosis were 31% more likely to have a longer life (HR 0.69; 95%CI 0.57-0.83). Early treatment of tuberculosis in HIV/AIDS patients can decrease mortality rates in southern Thailand.
Faculty of Health and Sports Science, Thaksin University, Phatthalung Campus, Phattalung, Thailand. bchaimay@gmail.com
Bhunyabhadh
B
Chaimay
Somkiattiyos
S
Woradet
Sawanya
S
Chantutanon
Supparaporn
S
Phuntara
Kannika
K
Suwanna
D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology* / Q000401:mortality; D000163:Acquired Immunodeficiency Syndrome / Q000401:mortality; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000401:mortality; D006801:Humans; D007223:Infant; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013785:Thailand / Q000453:epidemiology; D014376:Tuberculosis / Q000453:epidemiology* / Q000401:mortality; D055815:Young Adult