Sternoclavicular osteoradionecrosis following treatment for head and neck cancer.
Osteoradionecrosis (ORN) is a well described complication of radiation therapy (RT) for head and neck cancer (HNC), with a past reported incidence as high as 10-18% [1,4] mostly involving the mandible. ORN rarely involves the sternoclavicular complex in HNC patients treated with RT. Here, we present a case of HNC treated with combined (cytotoxic) chemotherapy and radiation therapy (CCRT) complicated by ORN and osteomyelitis of the sternoclavicular complex involving large segments of both clavicles, the sternum, and the trachea.
Department of Otolaryngology-Head & Neck Surgery, Case Western Reserve University School of Medicine & Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA.
Neal
N
Gehani
Adir
A
Ludin
Jonathan Z
JZ
Baskin
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D002968:Clavicle / Q000473:pathology / Q000601:surgery; D003646:Debridement; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D010025:Osteoradionecrosis / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D013247:Sternoclavicular Joint / Q000473:pathology* / Q000601:surgery; D013249:Sternum / Q000473:pathology / Q000601:surgery; D013524:Surgical Flaps; D014062:Tongue Neoplasms / Q000532:radiotherapy*
D000900:Anti-Bacterial Agents