Synthesis and characterization of novel stimuli-responsive hydrogels based on starch and L-aspartic acid.
Starch is a hydrophilic biopolymer that is desirable in synthesizing new hydrogels. L-Aspartic acid is a multifunctional amino acid that can be used to modify starch in order to introduce new functional groups on its chains. In this research, a series of novel natural hydrogels based on starch and L-aspartic acid have been synthesized. These hydrogels exhibited temperature-responsive swelling behavior, pH sensitivity and superabsorbency properties. They were characterized by Nuclear Magnetic Resonance (NMR), Infra-Red Spectroscopy (IR), and X-ray Diffraction (XRD). The thermal properties of the hydrogels were evaluated using Thermo-Gravimetric Analysis (TGA) and Differential Scanning Calorimetery (DSC). Swelling studies were carried out at various temperatures and pHs. All of the hydrogels exhibited a high swelling ratio; in aqueous media, this value was greater at higher pH than at lower pH. These properties introduce a novel carrier having applications in delivery systems.
Department of Chemistry, Firoozabad Branch, Islamic Azad University, Fars, Iran. Electronic address: mrvakili@gmail.com.
Mohammad Reza
MR
Vakili
Nahid
N
Rahneshin
D000327:Adsorption; D001224:Aspartic Acid / Q000737:chemistry*; D004337:Drug Carriers / Q000138:chemical synthesis* / Q000737:chemistry; D020100:Hydrogels / Q000138:chemical synthesis* / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D013213:Starch / Q000737:chemistry*; D013696:Temperature; D013818:Thermogravimetry; D014867:Water / Q000737:chemistry*
D004337:Drug Carriers; D020100:Hydrogels; D014867:Water; D001224:Aspartic Acid; D013213:Starch
Hydrogel; Starch; Stimuli-responsive; Superabsorbent; l-Aspartic acid