Effects of plateletpheresis on blood coagulation parameters in healthy donors at National Blood Centre, Kuala Lumpur, Malaysia.
Plateletpheresis is a method used to remove platelet from the body either from random volunteer donors, patient's family members or HLA matched donors. A cross sectional study was carried out on 59 plateletpheresis donors aged between 18 and 55 years at National Blood Center (NBC), Kuala Lumpur. We compared the blood parameters before and after plateletpheresis and we found that the platelet count, FVIII, fibrinogen and thrombophilia markers anti-thrombin (AT), protein C and protein S were significantly reduced (p<0.05) with prolonged PT and APTT. There were significant changes in blood coagulation parameters but it is within acceptable range.
Advanced Medical and Dental Institute (AMDI), Universiti Sains Malaysia, Pulau Pinang, Malaysia; National Blood Centre, Kuala Lumpur, Malaysia.
A K
AK
Siti Nadiah
M
M
Nor Asiah
A T
AT
Nur Syimah
M
M
Normi
E
E
Anza
A Nor
AN
Aini
T H
TH
Mohd Zahari
M
M
Shahnaz
A K
AK
Faraizah
M A
MA
Faisal
D000293:Adolescent; D000328:Adult; D001777:Blood Coagulation / Q000502:physiology*; D001782:Blood Donors; D005260:Female; D006801:Humans; D008296:Malaysia; D008297:Male; D008875:Middle Aged; D010983:Plateletpheresis / Q000379:methods*; D055815:Young Adult
Apheresis; Blood coagulation; Cell separator; Platelet; Plateletpheresis