Mixtures of L-amino acids as reaction medium for formation of iron nanoparticles: the order of addition into a ferrous salt solution matters.
Owing to Mössbauer spectroscopy, an advanced characterization technique for iron-containing materials, the present study reveals previously unknown possibilities using l-amino acids for the generation of magnetic particles. Based on our results, a simple choice of the order of l-amino acids addition into a reaction mixture containing ferrous ions leads to either superparamagnetic ferric oxide/oxyhydroxide particles, or magnetically strong Fe0-Fe2O3/FeOOH core-shell particles after chemical reduction. Conversely, when ferric salts are employed with the addition of selected l-amino acids, only Fe0-Fe2O3/FeOOH core-shell particles are observed, regardless of the addition order. We explain this phenomenon by a specific transient/intermediate complex formation between Fe2+ and l-glutamic acid. This type of complexation prevents ferrous ions from spontaneous oxidation in solutions with full air access. Moreover, due to surface-enhanced Raman scattering spectroscopy we show that the functional groups of l-amino acids are not destroyed during the borohydride-induced reduction. These functionalities can be further exploited for (i) attachment of l-amino acids to the as-prepared magnetic particles, and (ii) for targeted bio- and/or environmental applications where the surface chemistry needs to be tailored and directed toward biocompatible species.
Department of Physical Chemistry, Regional Centre of Advanced Technologies and Materials, Palacký University in Olomouc, 783 71 Olomouc, Czech Republic. radek.zboril@upol.cz.
Karolína M
KM
Šišková
Libor
L
Machala
Jiři
J
Tuček
Josef
J
Kašlík
Peter
P
Mojzeš
Radek
R
Zbořil
D000596:Amino Acids / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D008280:Magnetics / Q000379:methods; D053758:Nanoparticles / Q000737:chemistry*; D010084:Oxidation-Reduction; D012996:Solutions / Q000737:chemistry*
D000596:Amino Acids; D012996:Solutions; D007501:Iron