Deposition of metal nanoparticles on phospholipid multilayer membranes modified by gramicidin.
A planar dipalmitoyl phosphatidylcholine (DPPC) multilayer phospholipid membrane was structurally modified by introducing a transmembrane protein, gramicidin (up to 25 mol %), to study its effect on the metal nanoparticles deposited on the membrane. Without gramicidin, when 3-nm-thick Ag, Sn, Al, and Au were deposited, the nanoparticles hardly nucleated on the DPPC membrane in rigid gel state (except for Au); however, the gramicidin addition dramatically enhanced the DPPC membrane surface's affinity for metal atoms so that a dense array of metal (Ag, Sn, and Au) or metal-oxide (Al-oxide) nanoparticles was produced on the membrane surface. The particle sizes ranged from 3 to 15 nm depending on the metal and gramicidin concentration, whereas the particle density was strongly dictated by the gramicidin concentration. The proposed method provides a convenient, generally applicable synthesis route for preparing different metal or metal-oxide nanoparticles on a relatively robust biocompatible membrane.
Department of Materials Science and Engineering, Hanyang University , Seoul, 133-791 Korea.
Won Bae
WB
Han
Yongdeok
Y
Kim
Hyeun Hwan
HH
An
Hee-Soo
HS
Kim
Chong Seung
CS
Yoon
D006046:Gold / Q000737:chemistry*; D006096:Gramicidin / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D010743:Phospholipids / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D013499:Surface Properties; D014001:Tin / Q000737:chemistry*
D010743:Phospholipids; D006096:Gramicidin; D012834:Silver; D014001:Tin; D006046:Gold