An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst.
Highly efficient and eco-friendly protocol for the synthesis of bis(3-indolyl)methanes by the electrophilic substitution reaction of indole with aldehydes catalyzed by poly(4-vinylpyridinium)hydrogen sulfate was described. Excellent yields, shorter reaction times, simple work-up procedure, avoiding hazardous organic solvents, and reusability of the catalyst are the most obvious advantages of this method.
Department of Chemistry, National Institute of Technology, Warangal, Andhra Pradesh 506 004, India.
Janardhan
J
Banothu
Rajitha
R
Gali
Ravibabu
R
Velpula
Rajitha
R
Bavantula
Peter A
PA
Crooks