Hypothyroidism and iodine deficiency in an infant requiring total parenteral nutrition.
While iodine deficiency remains a relatively rare cause of thyroid dysfunction in the United States, little is known about iodine status and deficiency in children requiring parenteral nutrition (PN). This population may be at an elevated risk of thyroid dysregulation and neurodevelopmental sequelae due to low concentrations in typical PN formulations. Furthermore, with the widespread practice of switching from iodine-based antiseptics to chlorhexadine, previous inadvertent sources of iodine are being eliminated as well.
Internal Medicine/Pediatrics, University of Cincinnati Medical Center/Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio Katherine.Clarridge@cchmc.org.
Katherine Elizabeth
KE
Clarridge
Internal Medicine/Pediatrics, University of Cincinnati Medical Center/Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Erin E
EE
Conway
UC Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
John
J
Bucuvalas
D006801:Humans; D007037:Hypothyroidism / Q000209:etiology*; D007223:Infant; D007455:Iodine / Q000172:deficiency*; D008297:Male; D009752:Nutritional Status; D010289:Parenteral Nutrition, Total / Q000009:adverse effects*; D014131:Trace Elements / Q000172:deficiency*
D014131:Trace Elements; D007455:Iodine
minerals/trace elements nutrition; parenteral nutrition; pediatrics life cycle