The relationship between eosinophil and cardiac syndrome X.
OBJECTIVE
The pathophysiology of cardiac syndrome X (CSX) has not been clearly identified, although multiple abnormalities including microvascular spasm, endothelial dysfunction, and atherothrombosis have been reported. It is known that eosinophils play an important role in vasoconstruction and thrombosis. We aimed to compare the eosinophil counts in patients with CSX versus controls.


METHODS
This study included 50 patients with CSX (20 male, mean age 50.42 ± 9.6 years) and 30 control persons (10 male, mean age 49.16.11 ± 9.2 years). These participants underwent concurrent routine biochemical tests, and their eosinophil counts were obtained on whole blood count. These parameters were compared between groups.


RESULTS
Baseline characteristics of the study groups were comparable. Patients with CSX had a higher eosinophil count and mean platelet volume (MPV) value than the controls (339.4 ± 188 vs 132.7 ± 75 and 8.8 ± 0.2 vs 7.2 ± 0.1 fL; P < .001, respectively).


CONCLUSIONS
As a result, our study revealed a relationship between eosinophil count and MPV in patients with CSX.
Department of Cardiology, Bursa Yüksek İhtisas Education and Research Hospital, Bursa, Turkey drmehmetdemir@hotmail.com.
Mehmet
M
Demir
Department of Cardiology, Bursa Yüksek İhtisas Education and Research Hospital, Bursa, Turkey.
Muhammed
M
Şentürk
Department of Cardiology, Bursa Yüksek İhtisas Education and Research Hospital, Bursa, Turkey.
Mustafa
M
Kuzeytemiz
D000328:Adult; D004804:Eosinophils; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D063847:Mean Platelet Volume; D017566:Microvascular Angina / Q000097:blood*; D008875:Middle Aged
cardiac syndrome X; eosinophil; mean platelet volume; thrombosis; vasospasm