Surveillance of methicillin-resistant Staphylococcus aureus causing nosocomial infections in five medical centers of Monterrey, Nuevo León, México from 2005-2009.
OBJECTIVE
Staphylococcus aureus is a principal cause of human bacterial infection worldwide. The dissemination of antibiotic resistance among S. aureus strains is very import in the treatment of Staphylococcal infections. We undertook this study to identify methicillin-resistant Staphylococcus aureus (MRSA) clones responsible for nosocomial infection in five medical centers in Monterrey, Nuevo León (N.L.), México from 2005-2009.


METHODS
One hundred ninety MRSA strains collected from 2005-2009 from five hospitals affiliated with the Instituto Mexicano del Seguro Social (IMSS) in Monterrey, N.L., México were characterized by antimicrobial susceptibility, pulsed field gel electrophoresis (PFGE) and Staphylococcal Cassette Chromosome mec (SCCmec) typing.


RESULTS
Only one clone was present in the five hospitals (clone C); this clone is strongly associated with the New York-Japan clone (SCCmec II) with a broad resistance profile.


CONCLUSIONS
This study clearly documented the high ability for dissemination and the persistence of the New York-Japan clone in these centers.
Departamento de Evaluación de Vacunas, Instituto Nacional de Salud Pública, Cuernavaca, Mexico.
Maria Elena
ME
Velazquez-Meza
Margarita
M
Hernández-Salgado
Juan F
JF
Contreras-Cordero
Patricia
P
Pérez-Cortes
Licet
L
Villarreal-Treviño
D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D016521:Electrophoresis, Gel, Pulsed-Field; D006761:Hospitals; D006801:Humans; D016106:Methicillin Resistance; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification* / Q000302:isolation & purification / Q000378:metabolism; D008800:Mexico; D010802:Phylogeny; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology
MRSA; Mexico; New York/Japan Clone