Circuitous route to transcription regulation.
In this issue of Molecular Cell, Zhang and colleagues (2013) identify a new class of intron-derived circular RNAs (ciRNAs) and show that they have the potential to enhance transcription of their host gene.
Department of Genetics and Developmental Biology, Institute for Systems Genomics, University of Connecticut Health Center, Farmington, CT 06030, USA.
Mohan T
MT
Bolisetty
Brenton R
BR
Graveley
D004257:DNA Polymerase II / Q000235:genetics*; D006801:Humans; D012319:RNA Polymerase II / Q000235:genetics*; D062085:RNA, Long Noncoding / Q000235:genetics*; D014158:Transcription, Genetic
D062085:RNA, Long Noncoding; D012319:RNA Polymerase II; D004257:DNA Polymerase II