Metastatic castration-resistant prostate cancer hungers for leucine.
Affiliation of author: Institute of Cancer and Genetics, Cardiff University, Wales, United Kingdom.
Andrew R
AR
Tee
D051701:Activating Transcription Factor 4 / Q000378:metabolism*; D026923:Amino Acid Transport Systems, Basic / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D018931:Antineoplastic Agents, Hormonal / Q000494:pharmacology*; D006801:Humans; D007930:Leucine / Q000037:antagonists & inhibitors*; D008297:Male; D020360:Neoadjuvant Therapy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000503:physiopathology*; D011944:Receptors, Androgen / Q000378:metabolism*
C410798:AR protein, human; C497109:ATF4 protein, human; D026923:Amino Acid Transport Systems, Basic; D000596:Amino Acids; D018931:Antineoplastic Agents, Hormonal; D011944:Receptors, Androgen; C469951:SLC7A6 protein, human; D051701:Activating Transcription Factor 4; D007930:Leucine