Autologous fibrin sealant in tubeless percutaneous nephrolithotomy; a prospective study.
OBJECTIVE
To evaluate the efficacy of autologous single-donor fibrin glue after tubeless percutaneous nephrolithotomy (PCNL).


METHODS
Forty-three patients were planned for tubeless PCNL in a prospective cohort study and randomized in two groups with or without using fibrin glue. Randomization method was based on the computer-generated random numbers.


RESULTS
Transfusion, urinary leakage, or major complications were found in neither of the groups. There was no difference between two groups in stone free rate (P = .53), and changes in hemoglobin (P = .61) and serum creatinine (P = .63) level.


CONCLUSIONS
Although autologous fibrin glue did not play any significant role in improving results or decreasing complications after tubeless PCNL in our study, its use was safe and did not increase complications.
Urology and Nephrology Research Center, No. 103, 9th Boustan St., Pasdaran Ave., Tehran, Iran. nouralizadeh@yahoo.com.
Seyyed Amir Mohsen
SA
Ziaee
Reza
R
Sarhangnejad
Hassan
H
Abolghasemi
Peyman
P
Eshghi
Mohammad Hadi
MH
Radfar
Ali
A
Ahanian
Mehdi
M
Kardoust Parizi
Nasser
N
Amirizadeh
Akbar
A
Nouralizadeh
D000328:Adult; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009403:Nephrostomy, Percutaneous / Q000379:methods*; D011446:Prospective Studies; D014014:Tissue Adhesives / Q000627:therapeutic use*
D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives