The role of anesthetic drugs in liver apoptosis.
BACKGROUND
The modern practice of anesthesia is highly dependent ona group of anesthetic drugs which many of them are metabolized in the liver.


METHODS
The liver, of course, usually tolerates this burden. However, this is not always an unbroken rule. Anesthetic induced apoptosis has gained great concern during the last years; especially considering the neurologic system.


RESULTS
However, we have evidence that there is some concern regarding their effects on the liver cells. Fortunately not all the anesthetics are blamed and even some could be used safely, based on the available evidence.


CONCLUSIONS
Besides, there are some novel agents, yet under research, which could affect the future of anesthetic agents' fate regarding their hepatic effects.
Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Ali
A
Dabbagh
Samira
S
Rajaei
Anesthesiology; Apoptosis; Liver; Pharmacology