Autoimmune hypothyroidism presenting as pituitary hyperplasia.
Pituitary hyperplasia with hyperprolactinemia has been described as a rare presentation of primary hypothyroidism. A 12-y-old child presented with intermittent headache, easy fatigability, coarseness of facial features, and hoarseness of voice for 6 mo duration. Brain imaging findings showed pituitary hyperplasia; hormonal assessment revealed primary hypothyroidism and hyperprolactinemia. Pituitary hyperplasia regressed with thyroid hormone replacement therapy. This report describes an unusual case of pituitary hyperplasia with hyperprolactinemia secondary to primary hypothyroidism.
Department of Endocrinology and Metabolism, Narayana Medical College and Superspeciality Hospital, Nellore, 524003, India.
Rajendra Prasad
RP
Namburi
Takkolu Sriram
TS
Karthik
Amaresh Reddy
AR
Ponnala
D002648:Child; D050031:Hashimoto Disease / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D006965:Hyperplasia / Q000209:etiology; D008297:Male; D010902:Pituitary Gland / Q000473:pathology*; D013967:Thyroiditis, Autoimmune / Q000150:complications / Q000175:diagnosis*