Direct access to triazole-olefins through catalytic cycloaddition of azides to unsaturated aldehydes.
In situ formed dienamines as HOMO-raising dipolarophiles react with azides to afford the corresponding triazole-olefins in good to excellent yields via a catalytic inverse-electron-demand 1,3-dipolar cycloaddition process.
Department of Chemistry, National University of Singapore, Block S15, Level 5, 3 Science Drive 3, Singapore117543. chmwangj@nus.edu.sg.
Wenjun
W
Li
Qianfa
Q
Jia
Zhiyun
Z
Du
Jian
J
Wang
D000447:Aldehydes / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D061565:Cycloaddition Reaction; D015394:Molecular Structure; D014230:Triazoles / Q000737:chemistry*
D000447:Aldehydes; D000475:Alkenes; D001386:Azides; D014230:Triazoles