Pharmacogenomics: current applications and future prospects towards personalized therapeutics.
Personalized Medicine is more than just a metabolic activity of a person. Pharmacogenomics, pharmacogenetics, pharmacoproteomics, and metabolomics play an important role in the development of personalized medicines. Personalized medicine uses information about a person's genes, proteins, enzyme activities, and cellular environment to diagnose and treat disease, cancer included. A major problem of personalized medicine is the fact that there is no portable bedside and low-cost bioanalytical technology that can be used in close proximity to the patient. This technology could play a significant role in defining the dosage setting for subsets of the population. The success of the personalized therapy is possible through the application of technology, which can provide a bridge between metabolism status and an individual's response to a particular drug and therapeutic modality.
Laboratory of Biology, School of Medicine, University of Athens, Athens, Greece.
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Vaiopoulou
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Gazouli
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Karikas
D014408:Biomarkers, Tumor / Q000235:genetics*; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy*; D010597:Pharmacogenetics; D057285:Precision Medicine
D014408:Biomarkers, Tumor