On the Autistic Spectrum Disorder concordance rates of twins and non-twin siblings.
Using the Interactive Autism Network Research Database, the Autistic Spectrum Disorder concordance rates for twins and non-twin siblings were calculated. For males, females and both genders together, the concordance rate for dizygotic twins is approximately twice that of non-twin siblings. We also determined that the concordance rate for non-twin siblings decreases as the interval between pregnancies increases. Our results appear to indicate that the uterine environment may contribute to autism concordance rates.
Department of Physics and Astronomy, Wayne State University, Detroit, MI 48202, USA.
H V
HV
Bohm
M G
MG
Stewart
A M
AM
Healy
D001721:Birth Intervals / Q000706:statistics & numerical data*; D002659:Child Development Disorders, Pervasive / Q000453:epidemiology*; D004200:Diseases in Twins / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008954:Models, Biological; D035781:Siblings; D014427:Twins; D014599:Uterus / Q000502:physiology*