Targeting endothelial cells by gene therapy.
In this issue of Blood, Abel et al designed lentiviral vectors (LVs) enabling specific gene delivery into endothelial cells in vivo. This opens new perspectives for gene therapy of hereditary disorders, cardiovascular diseases, and cancer.
UNIVERSITY OF BRUSSELS;
Thierry
T
Vandendriessche
Marinee K
MK
Chuah
D000818:Animals; D001158:Arteries; D042783:Endothelial Cells / Q000378:metabolism*; D018014:Gene Transfer Techniques; D005822:Genetic Vectors / Q000235:genetics*; D006801:Humans; D008099:Liver