Extended-spectrum beta-lactamase-producing Enterobacteriaceae carriage upon hospital admission: prevalence and risk factors.
The aim of this study was to assess the value of surveillance cultures in identifying extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL) carriers upon admission to hospital, and to identify risk factors for carriage. This prospective cross-sectional study included all hospital admissions over one week. Of 525 patients screened, 56 were positive for ESBLs. Half were only identified through screening. Four independent risk factors were identified: nursing home residency, hospitalization in the previous year, prior antibiotic treatment and prior ESBL carriage. Over 50% of the screened patients had at least one risk factor. By screening this targeted population, 87.5% of positive patients would have been identified.
Infectious Diseases Unit, Meir Medical Centre, Kfar Saba, Israel; Sackler Medical School, Tel-Aviv University, Tel-Aviv, Israel.
P
P
Shitrit
S
S
Reisfeld
Y
Y
Paitan
B-S
BS
Gottesman
M
M
Katzir
M
M
Paul
M
M
Chowers
D000368:Aged; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology; D003430:Cross-Sectional Studies; D003955:Diagnostic Tests, Routine; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D001618:beta-Lactamases / Q000378:metabolism*
D001618:beta-Lactamases
ESBL; Risk factors; Surveillance