An iridium(III)-based lab-on-a-molecule for cysteine/homocysteine and tryptophan using triple-channel interrogation.
Iridium complex is a lab-on-a-molecule for recognising and quantifying cysteine/homocysteine and tryptophan in a mixture of all proteinogenic amino acids. UV-Vis and photoluminescence channels are suitable for quantification of homocysteine and cysteine in aqueous media, e.g. by emission enhancement at 606 nm, while tryptophan was selectively quantified in the electrochemiluminescence channel.
Center for Micro- and Nanochemistry and Engineering, Organische Chemie, Universität Siegen, Adolf-Reichwein-Strasse, D-57068, Siegen, Germany. schmittel@chemie.uni-siegen.de.
Kun
K
Chen
Michael
M
Schmittel
D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D056831:Coordination Complexes / Q000737:chemistry; D003545:Cysteine / Q000032:analysis*; D006710:Homocysteine / Q000032:analysis*; D007495:Iridium / Q000737:chemistry*; D056656:Lab-On-A-Chip Devices; D014364:Tryptophan / Q000032:analysis*
D056831:Coordination Complexes; D006710:Homocysteine; D007495:Iridium; D014364:Tryptophan; D003545:Cysteine