Changes in plasma pyridoxal 5'-phosphate concentration during pregnancy stages in Japanese women.
Most Japanese women do not consume the estimated average requirement of vitamin B6 (1.7 mg/d) during pregnancy. Nevertheless, these deficiencies are not reported. We investigated a nutritional biomarker of vitamin B6 in pregnant Japanese women as well as their vitamin B6 intakes. Vitamin B6 intakes in the first, second, and third trimesters of pregnancy, and 1 mo after delivery were 0.79±0.61 (n=56), 0.81±0.29 (n=71), 0.90±0.35 (n=92), and 1.00±0.31 (n=44) mg/d, respectively. Plasma pyridoxal 5'-phosphate (PLP) concentrations in the first, second, and third trimesters of pregnancy, and 1 mo after delivery were 57.1±27.6 (n=56), 23.3±16.7 (n=71), 18.3±12.5 (n=92), and 43.9±33.4 (n=44) nmol/L, respectively. The plasma concentrations significantly decreased in the second and third trimesters of pregnancy compared to values from the first trimester (p<0.05), and these concentrations returned to the values of the first trimester of pregnancy 1 mo after birth.
Department of Nutrition, School of Human Cultures, The University of Shiga Prefecture.
Katsumi
K
Shibata
Akiko
A
Tachiki
Kana
K
Mukaeda
Tsutomu
T
Fukuwatari
Satoshi
S
Sasaki
Yoshiki
Y
Jinno
D000328:Adult; D044466:Asian People; D015415:Biomarkers / Q000097:blood; D004032:Diet; D005260:Female; D006801:Humans; D007564:Japan; D039382:Maternal Nutritional Physiological Phenomena; D009751:Nutritional Requirements; D011247:Pregnancy; D011264:Pregnancy Trimesters; D011732:Pyridoxal Phosphate / Q000097:blood*; D025101:Vitamin B 6 / Q000008:administration & dosage* / Q000097:blood; D026681:Vitamin B 6 Deficiency / Q000097:blood
D015415:Biomarkers; D011732:Pyridoxal Phosphate; D025101:Vitamin B 6