Surgical treatment of recurring ameloblastoma, are there options?
Our aim was to evaluate the treatment given to patients with intraosseus ameloblastomas with special emphasis on recurrence and the outcomes of primary and secondary resection. Forty-eight patients who were treated for intraosseous ameloblastoma at 8 centres across Sweden met the inclusion criteria. They showed typical distribution of age, sex, site of lesion, and characteristic presenting features. Eleven of the 48 were initially treated with radical resection and none recurred. Twenty-two of the remaining 37 who were initially treated by conservative resection presented with recurrences. Sixteen of the 22 then had conservative secondary resections, which resulted in further recurrence in 6 patients. Initial radical resection is therefore superior to conservative management as far as recurrences are concerned. We argue, however, that a conservative surgical approach is adequate for many intraosseous ameloblastomas with limited extension, because relapse can be followed by radical resection if clinically indicated in selected cases.
Department of Oral and Maxillofacial Surgery, Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden; Center for Infectious Medicine, F59, Department of Medicine, Huddinge, Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden.
Oscar
O
Hammarfjord
Johan
J
Roslund
Peter
P
Abrahamsson
Peter
P
Nilsson
Andreas
A
Thor
Mikael
M
Magnusson
Göran
G
Kjeller
Charlotta
C
Englesson-Sahlström
Tomas
T
Strandkvist
Gunnar
G
Warfvinge
Carina
C
Krüger-Weiner
D000293:Adolescent; D000328:Adult; D000564:Ameloblastoma / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007573:Jaw Neoplasms / Q000601:surgery*; D008297:Male; D008339:Mandibular Neoplasms / Q000601:surgery; D008441:Maxillary Neoplasms / Q000601:surgery; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D010027:Osteotomy / Q000379:methods; D012086:Reoperation; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
Ameloblastoma; Odontogenic neoplasm; Recurrent ameloblastoma