[The factors that require short acting beta-blockers during general anesthesia using remifentanil].
BACKGROUND
Short acting beta-blockers (SBB) have been utilized effectively to prevent adverse cardiac events perioperatively. After recent introduction of remifentanil in Japan, applications of SBB could have been changed because of its intense analgesic and negative chronotrophic effects. Thus, we evaluated the factors that require SBB during general anesthesia using remifentanil.


METHODS
Total of 1,631 patients who had general anesthesia with remifentanil were enrolled. Groups were divided by the use of SBB. Using logistic multivariable analysis, the factors significantly increasing the chance of using SBB were evaluated including patients' characteristics, surgical procedures, and anesthetic methods. A P value < 0.05 was considered as statistical significance.


RESULTS
One hundred thirty one patients received SBB perioperatively, 94 of them received only when awake and 34 of them received during remifentanil anesthesia. Emergency operation and preoperative ECG abnormalities were significant factors requiring SBB during anesthesia using remifentanil (OR; 3.0, 4.9 respectively).


CONCLUSIONS
Even with use of remifentanil there are the patients, such as those under emergency operation or with ECG abnormalities who require SBB perioperatively.
Department of Anesthesiology, Nagasaki University School of Medicine, Nagasaki 852-8501.
Mai
M
Okada
Tetsuya
T
Hara
Sungsam
S
Cho
Koji
K
Sumikawa
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000768:Anesthesia, General / Q000379:methods; D004630:Emergencies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D059035:Perioperative Period; D010880:Piperidines; D000077208:Remifentanil; D013610:Tachycardia / Q000150:complications
D000319:Adrenergic beta-Antagonists; D010880:Piperidines; D000077208:Remifentanil