[Analysis of polymorphisms of mitochondrial DNA in 3 ethnic groups of Guizhou].
OBJECTIVE
To analyze the population genetics characteristics of mitochondrial DNA (mtDNA) in Gelao, Mulao, Maonan ethnic groups from Guizhou.


METHODS
Minisequenceing and restriction fragment length polymorphism (RFLP) were used to analyze 12 single nucleotide polymorphism (SNPs) of mitochondrial DNA in the 3 ethnic groups.


RESULTS
A total of 30 haplotypes were detected in 156 samples. The distribution of H1, H23 had differed between Mulao, Maonan and Gelao, respectively, and so did M7 among the three groups. The difference was statistically significant (P < 0.05). Mulao, Maonan had respectively differed from Gelao and the difference was also statistically significant (P < 0.05).


CONCLUSIONS
There was a great similarity in the distribution of haplotypes of the mtDNA among the three ethnic groups, except for some difference in the distribution of certain haplotypes.
Key Laboratory of Molecular Biology, Guiyang Medical University, Guiyang, Guizhou 550004, P. R. China. Email: annieheyan@gmc.edu.cn.
Ling-yan
LY
Ren
Yan
Y
He
Ting
T
Zhang
Chan-juan
CJ
Wang
Zhi-zhong
ZZ
Guan
Keren
K
Shan
D044466:Asian People / Q000208:ethnology* / Q000235:genetics*; D002681:China / Q000208:ethnology; D004272:DNA, Mitochondrial / Q000235:genetics*; D006801:Humans; D008297:Male; D010375:Pedigree; D011110:Polymorphism, Genetic
D004272:DNA, Mitochondrial