Runaway transcription.
A newly demonstrated defect in RNA polymerase II termination caused by 7SK snRNA knockdown may have revealed a novel mechanism uncoupling RNA processing from transcription.
Jiannan
J
Guo
Tiandao
T
Li
David H
DH
Price
D020413:3' Untranslated Regions; D000818:Animals; D002843:Chromatin / Q000737:chemistry / Q000378:metabolism; D053595:Embryonic Stem Cells / Q000166:cytology / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D056426:Genetic Loci; D016678:Genome; D051379:Mice; D026723:Polyadenylation; D011401:Promoter Regions, Genetic; D012319:RNA Polymerase II / Q000235:genetics* / Q000378:metabolism; D034741:RNA, Small Interfering / Q000235:genetics / Q000378:metabolism; D012342:RNA, Small Nuclear / Q000037:antagonists & inhibitors / Q000235:genetics* / Q000378:metabolism; D061806:Transcription Termination, Genetic
D020413:3' Untranslated Regions; D002843:Chromatin; D034741:RNA, Small Interfering; D012342:RNA, Small Nuclear; D012319:RNA Polymerase II