[Chemichal desympathization in the treatment of throphic ulcer in patients with varicose veins of the lower limbs].
The in vivo study on 25 rabbits and clinical study, involving 60 patients with lower limbs' varicose disease and trophic ulcers was carried out. The in-vivo study was based on the chemical distruction of the sympathic trunk by injecting 95% ethanol and 6% phenol paraneurally along the vascular bundle in the ear. The regeneration of the sympathic neural trunk was registered within 2-3 months after the injury. In human patients the US-guided chemical desympathization led to the increase of the capillary circulation (1.9 times at rest and 0.3 times under the load) during 2 months. The fact favoured the faster regress of inflammatory process in the ulcer.
B S
BS
Sukovatykh
M B
MB
Sukovatykh
A I
AI
Itinson
V V
VV
Kniazev
D000328:Adult; D000368:Aged; D000818:Animals; D004195:Disease Models, Animal; D000431:Ethanol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D008991:Monitoring, Physiologic / Q000379:methods; D019800:Phenol / Q000627:therapeutic use*; D011817:Rabbits; D012039:Regional Blood Flow; D012597:Sclerosing Solutions / Q000627:therapeutic use; D013563:Sympathectomy, Chemical / Q000379:methods*; D016896:Treatment Outcome; D014647:Varicose Ulcer / Q000601:surgery*; D014648:Varicose Veins / Q000601:surgery*; D014945:Wound Healing
D012597:Sclerosing Solutions; D019800:Phenol; D000431:Ethanol