The Moran model with selection: fixation probabilities, ancestral lines, and an alternative particle representation.
We reconsider the Moran model in continuous time with population size N, two allelic types, and selection. We introduce a new particle representation, which we call the labelled Moran model, and which has the same distribution of type frequencies as the original Moran model, provided the initial values are chosen appropriately. In the new model, individuals are labelled 1,2,…,N; neutral resampling events may take place between arbitrary labels, whereas selective events only occur in the direction of increasing labels. With the help of elementary methods only, we not only recover fixation probabilities, but also obtain detailed insight into the number and nature of the selective events that play a role in the fixation process forward in time.
Faculty of Technology, Bielefeld University, Box 100131, 33501 Bielefeld, Germany.
Sandra
S
Kluth
Ellen
E
Baake
D008957:Models, Genetic; D011336:Probability
Ancestral line; Defining event; Fixation probability; Labelled Moran model; Moran model with selection