Emotional reactivity and its impact on neural circuitry for attention-emotion interaction in childhood and adolescence.
Attention modulation when confronted with emotional stimuli is considered a critical aspect of executive function, yet rarely studied during childhood and adolescence, a developmental period marked with changes in these processes. We employed a novel, and child-friendly fMRI task that used emotional faces to investigate the neural underpinnings of the attention-emotion interaction in a child and adolescent sample (n=23, age M=13.46, SD=2.86, range=8.05-16.93 years). Results implied modulation of activation in the orbitofrontal cortex (OFC) due to emotional distractor valence, which marginally correlated with participant age. Additionally, parent-reported emotional reactivity predicted the trajectory of BOLD signal increase for fearful emotional face distractors such that participants low in emotional reactivity had a steeper latency to peak activation. Results imply that the use of the OFC to modulate attention in the face of social/emotional stimuli may mature with age and may be tightly coupled with adaptive emotional functioning. Findings are discussed in the context of risk for the development of psychiatric disorders, where increased emotional reactivity is particularly apparent.
University of Pittsburgh Department of Psychiatry, United States. Electronic address: perlmansb2@upmc.edu.
Susan B
SB
Perlman
University of Pittsburgh Department of Psychiatry, United States.
Tyler C
TC
Hein
University of Pittsburgh Department of Psychiatry, United States.
Stephanie D
SD
Stepp
D000293:Adolescent; D000375:Aging / Q000523:psychology; D001288:Attention / Q000502:physiology*; D002648:Child; D004644:Emotions / Q000502:physiology*; D056344:Executive Function; D005149:Facial Expression; D005239:Fear / Q000523:psychology; D005260:Female; D005625:Frontal Lobe / Q000502:physiology / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009434:Neural Pathways / Q000502:physiology*; D010775:Photic Stimulation
Adolescence; Attention; Development; Emotion; Emotional reactivity; Orbitofrontal cortex