Visual outcomes of Femto-LASIK for correction of residual refractive error after corneal graft.
OBJECTIVE
To evaluate the outcomes of the Femto-LASIK method in the treatment of refractive errors following penetrating keratoplasty (PK) at the Persian Eye Clinic, Isfahan, Iran


METHODS
In a prospective, non-comparative case series, 34 consecutive symptomatic eyes of 34 patients after corneal graft, were operated on. Tissue-saving (TS) Femto-LASIK (n = 16), and Zyoptix Personalized Treatment Advanced (PTA) Femto-LASIK (n = 18) were performed using the Bausch & Lomb Technolas 217z excimer laser and Zyoptic algorithm. Uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), manifest refraction, contrast sensitivity, and HOAs were evaluated preoperatively and 12 months after enhancement treatment.


RESULTS
At 12 months, the mean preoperative myopic spherical equivalent refraction (SE) decreased from -6.50 ± 2.8 D to -1.6 ± 1.8 D, and mean hyperopic SE from +3.2 ± 2.20 D to 0.37 ± 1.2 D. The safety index was 1.42 (1.2 in the TS group and 1.5 in the PTA group). In the TS group, 100% of eyes achieved 20/80 or better UCVA and 50%, 20/40 or better and in the PTA group, 100% of eyes achieved 20/80 or better UCVA and 77.7%, 20/40 or better. The efficacy index was 1.08 (0.9 in TS group and 1.21 in the PTA group). Patients obtained statistically significant lower values of root mean square (RMS) of HOAs with spherical aberrations (p < 0.05).


CONCLUSIONS
Femto-LASIK method with Zyoptic programs after PK was safe, effective, and predictable for correction of spherical and cylindrical components of the refractive error.
Isfahan University of Medical Sciences, Isfahan, Iran.
Mohammad
M
Ghoreishi
Afsaneh
A
Naderi Beni
Zahra
Z
Naderi Beni
D000328:Adult; D000465:Algorithms; D001251:Astigmatism / Q000209:etiology / Q000601:surgery; D015350:Contrast Sensitivity / Q000502:physiology; D005260:Female; D005642:Fuchs' Endothelial Dystrophy / Q000601:surgery; D006801:Humans; D006956:Hyperopia / Q000209:etiology / Q000601:surgery*; D007640:Keratoconus / Q000601:surgery; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000209:etiology / Q000601:surgery*; D011446:Prospective Studies; D012029:Refraction, Ocular / Q000502:physiology; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology*; D055815:Young Adult