A selective fluorescent chemosensor for phosphoserine.
A fluorescent chemosensor for the detection of phosphoserine is reported. The ditopic sensor features a phosphate-coordinating zinc(II)-dipicolylamine (Zn(2+)-DPA) unit tethered to an amine-binding coumarin aldehyde fluorophore. With phosphoserine, the sensor demonstrates a 30-fold fluorescence enhancement under buffered aqueous conditions.
Department of Chemistry, University of Missouri, 601 South College Avenue, Columbia, MO 65211, USA. GlassT@missouri.edu.
Chad M
CM
Cooley
Kenneth S
KS
Hettie
Jessica L
JL
Klockow
Shana
S
Garrison
Timothy E
TE
Glass
D000588:Amines / Q000737:chemistry; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D005456:Fluorescent Dyes / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010710:Phosphates / Q000737:chemistry; D010768:Phosphoserine / Q000032:analysis* / Q000737:chemistry; D010848:Picolinic Acids / Q000737:chemistry
C501847:2,2'-dipicolylamine; D000588:Amines; D005456:Fluorescent Dyes; D009942:Organometallic Compounds; D010710:Phosphates; D010848:Picolinic Acids; D010768:Phosphoserine