Relation of neutrophil-to-lymphocyte ratio with GRACE risk score to in-hospital cardiac events in patients with ST-segment elevated myocardial infarction.
In this study, we aimed to investigate the association of the neutrophil-to-lymphocyte ratio (NLR) with Global Registry of Acute Coronary Events (GRACE) risk score in patients with ST-segment elevated myocardial infarction (STEMI). We analyzed 101 consecutive patients with STEMI. Patients were divided into 3 groups by use of GRACE risk score. The association between NLR and GRACE risk score was assessed. The NLR showed a proportional increase correlated with GRACE risk score (P < .001). The occurrence of in-hospital cardiac death, reinfarction, or new-onset heart failure was significantly related to NLR at admission (P < .001). Likewise, NLR and GRACE risk score showed a significant positive correlation (r = .803, P < .001). In multivariate analysis, NLR resulted as a predictor of worse in-hospital outcomes independent of GRACE risk score. Our study suggests that the NLR is significantly associated with adverse in-hospital outcomes, independent of GRACE risk score in patients with STEMI.
Department of Cardiology, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
Ramazan Can
RC
Oncel
Department of Cardiology, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
Mustafa
M
Ucar
Department of Cardiology, Nigde State Hospital, Nigde, Turkey mserkan19@hotmail.com.
Mustafa Serkan
MS
Karakas
Department of Cardiology, Burdur State Hospital, Burdur, Turkey.
Baris
B
Akdemir
Department of Cardiology, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
Atakan
A
Yanikoglu
Department of Cardiology, Sanliurfa Research and Education Hospital, Sanliurfa, Turkey.
Ali Riza
AR
Gulcan
Department of Cardiology, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
Refik Emre
RE
Altekin
Department of Cardiology, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
Ibrahim
I
Demir
D000328:Adult; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000209:etiology / Q000401:mortality; D017052:Hospital Mortality; D006801:Humans; D018655:Lymphocyte Count; D008214:Lymphocytes; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000150:complications / Q000401:mortality; D009504:Neutrophils; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors
GRACE risk score; acute myocardial infarction; inflammation; neutrophil-to-lymphocyte ratio