Synthesis of highly functionalized macrocycles by tandem multicomponent reactions and intramolecular Sonogashira cross-coupling.
An efficient chemoselective process for the synthesis of 14- and 15-membered triazole-containing macrocycle compounds has been developed through the combination of two multicomponent reactions and an intramolecular Sonogashira cross-coupling reaction.
Chemical Engineering College, Nanjing University of Science and Technology, Nanjing, 210094, P. R. China. c.cai@mail.njust.edu.cn.
Teng-fei
TF
Niu
Mu
M
Sun
Mei-fang
MF
Lv
Wen-bin
WB
Yi
Chun
C
Cai
D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry
D047028:Macrocyclic Compounds; D014230:Triazoles