Depressive syndromes in neurological disorders.
Depressive syndromes represent a common and often characteristic feature in a number of neurological disorders. One prominent example is the development of post-stroke depression, which can be observed in more than one-third of stroke survivors in the aftermath of an ischemic stroke. Thus, post-stroke depression represents one of the most prevalent, disabling, and potentially devastating psychiatric post-stroke complications. On the other hand, depressive syndromes may also be considered as a risk factor for certain neurological disorders, as recently revealed by a meta-analysis of prospective cohort studies, which demonstrated an increased risk for ischemic events in depressed patients. Moreover, depressive syndromes represent common comorbidities in a number of other neurological disorders such as Parkinson's disease, multiple sclerosis, or epilepsy, in which depression has a strong impact on both quality of life and outcome of the primary neurological disorder.
Julian
J
Hellmann-Regen
Dominique
D
Piber
Kim
K
Hinkelmann
Stefan M
SM
Gold
Christoph
C
Heesen
Carsten
C
Spitzer
Matthias
M
Endres
Christian
C
Otte
D003866:Depressive Disorder / Q000453:epidemiology / Q000209:etiology* / Q000523:psychology* / Q000628:therapy; D004827:Epilepsy / Q000150:complications / Q000453:epidemiology / Q000523:psychology; D006801:Humans; D009103:Multiple Sclerosis / Q000150:complications / Q000453:epidemiology / Q000523:psychology; D009422:Nervous System Diseases / Q000150:complications* / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy; D010300:Parkinson Disease / Q000150:complications / Q000453:epidemiology / Q000523:psychology; D012307:Risk Factors; D020521:Stroke / Q000150:complications / Q000453:epidemiology / Q000523:psychology