[A new method for measuring pulmonary function parameters].
OBJECTIVE
To propose a new method for acquiring pulmonary function parameters based on measurement of volume changes of thoracic impedance.


METHODS
We studied the relationship between the volume changes of thoracic impedance and pulmonary function parameters during forced breathing based on bioimpedance measurement, and developed an instrument for measuring thoracic impedance. Using this instrument and a MRI spirolab III lung function test instrument, both based on flowmeter measurement, we measured such pulmonary function parameters including forced vital capacity (FVC), forced expiratory volume in one second/FVC (FEV1/FVC), and peak expiratory flow in 10 healthy volunteers and compared the measurement results.


RESULTS
The differences in the parameters measured using the two instruments were all within two folds of the positive and negative standard deviations of the average values, demonstrating good consistency in the measurement between the two methods.


CONCLUSIONS
The measurement results of the bioimpedance-based instrument we developed show good consistency with those by the commercially available pulmonary function test instrument.
Institute of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.E-mail: 361879471@qq.com.
Jianming
J
Yang
Shenghe
S
Zhong
Feixue
F
Liang
Jinsong
J
Guo
Weilong
W
Li
Jinming
J
Li
D000328:Adult; D017097:Electric Impedance; D005541:Forced Expiratory Volume; D006801:Humans; D010366:Peak Expiratory Flow Rate; D012129:Respiratory Function Tests / Q000379:methods*; D013909:Thorax / Q000502:physiology*; D014797:Vital Capacity; D055815:Young Adult