Treatment of anterior vaginal wall prolapse with and without polypropylene mesh: a prospective, randomized and controlled trial - Part II.
OBJECTIVE
To compare the effects of two surgical procedures for the correction of anterior vaginal wall prolapse (AVWP) on the lower urinary tract symptoms (LUTS) using symptom questionnaires and quality of life (QoL).


METHODS
One hundred women with Pelvic Organ Prolapse Quantification stage (POP-Q) ≥ 2 were randomly distributed in two preoperatory groups. The first group (mesh) (n = 45) received a polypropylene mesh (PM) implant and the control group (n = 55) was submitted to anterior colporraphy with or without synthetic sling. Postoperatory follow-up was done after 12 months. The primary objective was to compare the effect of the surgeries on LUTS using the final scores of the International Consultation on Incontinence Questionnaire Urinary Incontinence Short Form (ICIQ-UI SF) and Overactive Bladder Questionnaire (OAB-V8), as well as the analysis of the incapacitating urinary symptoms and ″de novo″ urinary symptoms after 12 months of surgery in both groups.


RESULTS
Although there was a different number of women in each group, randomization was adequate, resulted in homogeneous groups that could be compared regarding socio demographic, clinical and gynecological (POP-Q) variables. Patients of both groups showed improvements regarding LUTS and QoL, whether using polypropylene mesh or not, based on the final scores of the ICIQ-UI SF and OAB-V8 questionnaires after 12-month follow-up. There were few incapacitating and ″de novo ″ urinary symptoms, without any significant statistical difference between both groups after 12 months of surgery.


CONCLUSIONS
There was a general improvement of LUTS and QoL in both groups after 12-month follow-up. However, there was no significant difference of LUTS, as well as the more incapacitating and ″de novo ″ urinary symptoms between both groups after 12 months of surgery.
Department of Medicine, Federal University of Sao Carlos, Sao Carlos, Sao Carlos, SP, Brazil.
José Tadeu Nunes
JT
Tamanini
Renata Cristina de Oliveira Souza
RC
Castro
Juliana Milhomem
JM
Tamanini
Paulo Cezar
PC
Feldner
Rodrigo de Aquino
Rde A
Castro
Marair Gracio Ferreira
MG
Sartori
Manoel João Batista Castello
MJ
Girão
D000368:Aged; D000369:Aged, 80 and over; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000534:rehabilitation / Q000601:surgery*; D008875:Middle Aged; D011126:Polypropylenes / Q000627:therapeutic use*; D011446:Prospective Studies; D011788:Quality of Life; D012016:Reference Values; D016037:Single-Blind Method; D013526:Surgical Mesh; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000534:rehabilitation / Q000601:surgery; D014596:Uterine Prolapse / Q000534:rehabilitation / Q000601:surgery*
D011126:Polypropylenes