Human papillomavirus-associated plantar epidermoid cysts: MR and US imaging appearance.
Epidermoid cysts are epithelial cysts that present as slow-growing intradermal or subcutaneous lesions. While recent epidemiological studies have isolated human papillomavirus (HPV) from plantar epidermoid cysts, imaging findings in HPV-associated epidermoid cysts have not been previously reported. We describe imaging findings in two patients with HPV-associated plantar epidermoid cysts. Magnetic resonance (MR) imaging and ultrasonography (US) showed linear arrangement of several adjacent globular cysts. This appearance is hypothesized to result from HPV-associated eccrine duct metaplasia leading to cyst formation and later traumatic rupture leading to formation of multiple adjacent cystic components. It may be useful to suggest assessing the presence of HPV antigen in plantar lesions having these imaging findings.
Department of Radiology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan, maroty0507@gmail.com.
Yoshinao
Y
Sato
Taiki
T
Nozaki
Masaki
M
Matsusako
Hikaru
H
Eto
Mizuko
M
Matsui
Naoyuki
N
Ohtake
Koyu
K
Suzuki
Jay
J
Starkey
Yukihisa
Y
Saida
D000293:Adolescent; D000328:Adult; D052685:Alphapapillomavirus / Q000302:isolation & purification*; D004814:Epidermal Cyst / Q000175:diagnosis* / Q000821:virology*; D005260:Female; D005534:Foot Diseases / Q000175:diagnosis* / Q000821:virology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D014463:Ultrasonography / Q000379:methods*