Prevalence of melioidosis in patients with suspected pulmonary tuberculosis and sputum smear negative for acid-fast bacilli in northeast Thailand.
The clinical and radiological features of pulmonary melioidosis can mimic tuberculosis. We prospectively evaluated 118 patients with suspected pulmonary tuberculosis who were acid-fast bacilli (AFB) smear negative at Udon Thani Hospital, northeast Thailand. Culture of residual sputum from AFB testing was positive for Burkholderia pseudomallei in three patients (2.5%; 95% confidence interval [CI] 0.5-7.3%). We propose that in melioidosis-endemic areas, residual sputum from AFB testing should be routinely cultured for B. pseudomallei.
Pornpan
P
Suntornsut
Kriangsak
K
Kasemsupat
Santi
S
Silairatana
Gumphol
G
Wongsuvan
Yaowaruk
Y
Jutrakul
Vanaporn
V
Wuthiekanun
Nicholas P J
NPJ
Day
Sharon J
SJ
Peacock
Direk
D
Limmathurotsakul
D000368:Aged; D001431:Bacteriological Techniques; D016957:Burkholderia pseudomallei / Q000302:isolation & purification*; D003470:Culture Media; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008554:Melioidosis / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D008875:Middle Aged; D009169:Mycobacterium tuberculosis; D015995:Prevalence; D011446:Prospective Studies; D013183:Sputum / Q000382:microbiology*; D013785:Thailand / Q000453:epidemiology; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology
D003470:Culture Media