Seroprevalence of human herpesvirus-8 in HIV-1 infected and uninfected individuals in Cameroon.
We evaluated the prevalence of HHV-8 antibodies in 516 plasma samples collected from HIV positive and negative patients from blood banks and urban areas of Cameroon. Among HIV-1 positive samples, HHV-8 seropositivity rate was 61% based on combined reactivity using both ELISA and IFA techniques. HIV negative samples showed 62% seropositivity rate for HHV-8 antibodies. Our results indicate a high HHV-8 prevalence rate in both HIV infected and uninfected individuals in Cameroon.
Division of Emerging and Transmission Transmitted Diseases, Office of Blood Review and Research, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852, USA. Christelle.Mbondji@fda.hhs.gov
Christelle
C
Mbondji-Wonje
Viswanath
V
Ragupathy
Sherwin
S
Lee
Owen
O
Wood
Bih
B
Awazi
Indira K
IK
Hewlett
D000328:Adult; D000914:Antibodies, Viral / Q000276:immunology*; D002163:Cameroon / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000276:immunology*; D015497:HIV-1 / Q000276:immunology* / Q000302:isolation & purification; D006566:Herpesviridae Infections / Q000453:epidemiology* / Q000276:immunology*; D019288:Herpesvirus 8, Human / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D016036:Seroepidemiologic Studies
D000914:Antibodies, Viral