Chemically triggered C-ON bond homolysis of alkoxyamines. 8. Quaternization and steric effects.
The C-ON bond homolysis in alkoxyamine 2a was chemically triggered by quaternization of the 1-(pyridin-2-yl)ethyl fragment using protonation, acylation, and oxidation into the N-oxide. The solvent effect was also investigated, and DFT calculations were performed to explore this chemical activation. Alkoxyamines 2a-d were also compared to the 1-(pyridin-4-yl)ethyl analogues 3a-d.
Aix-Marseille Université, CNRS, Institut de Chimie Radicalaire UMR 7273, Avenue Escadrille Normandie-Niemen, 13397 Marseille cedex 20, France.
Gérard
G
Audran
Lionel
L
Bosco
Paul
P
Brémond
Sylvain R A
SR
Marque
Valérie
V
Roubaud
Didier
D
Siri