From amputation to limb salvage reconstruction: evolution and role of the endoprosthesis in musculoskeletal oncology.
In 1943, Austin Moore developed the first endoprosthesis fashioned from Vitallium, providing the first alternative to traditional amputation as primary treatment of bone tumors. The success of the Vitallium endoprosthesis has since then led to the development of new materials and designs further advancing limb salvage and reconstructive surgery. Combined with the advent of chemotherapy use and imaging advances, conservative treatment of musculoskeletal tumors has expanded greatly. As the implantable options increased with the development of the Lewis expandable adjustable prosthesis and the noninvasive Phenix Growing prosthesis, receiving the diagnosis of a bone tumor no longer equates to automatic limb loss. Our review details the history and development of endoprostheses throughout orthopedic oncology in the treatment of musculoskeletal tumors.
Division of Orthopaedic Oncology, Department of Orthopaedic Surgery, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07101, USA, jhwang12@gmail.com.
John S
JS
Hwang
Anokhi D
AD
Mehta
Richard S
RS
Yoon
Kathleen S
KS
Beebe
D000671:Amputation, Surgical; D001186:Artificial Limbs; D001859:Bone Neoplasms / Q000601:surgery*; D006801:Humans; D023821:Limb Salvage; D011474:Prosthesis Design; D019919:Prosthesis Implantation; D019651:Plastic Surgery Procedures