[Tubular renal acidosis].
Renal tubular acidosis (RTAs) are a group of metabolic disorders characterized by metabolic acidosis with normal plasma anion gap. There are three main forms of RTA: a proximal RTA called type II and a distal RTA (type I and IV). The RTA type II is a consequence of the inability of the proximal tubule to reabsorb bicarbonate. The distal RTA is associated with the inability to excrete the daily acid load and may be associated with hyperkalaemia (type IV) or hypokalemia (type I). The most common etiology of RTA type IV is the hypoaldosteronism. The RTAs can be complicated by nephrocalcinosis and obstructive nephrolithiasis. Alkalinization is the cornerstone of treatment.
Université Versailles Saint-Quentin-en-Yvelines, 78000 Versailles, France; Service de médecine interne, hôpital Ambroise-Paré, AP-HP, 92104 Boulogne-Billancourt cedex, France; Service de néphrologie, hôpital Ambroise-Paré, AP-HP, 92104 Boulogne-Billancourt cedex, France. Electronic address: alexandre.seidowsky@apr.aphp.fr.
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Seidowsky
Service de néphrologie, hôpital Ambroise-Paré, AP-HP, 92104 Boulogne-Billancourt cedex, France.
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Moulonguet-Doleris
Université Versailles Saint-Quentin-en-Yvelines, 78000 Versailles, France; Service de médecine interne, hôpital Ambroise-Paré, AP-HP, 92104 Boulogne-Billancourt cedex, France.
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Hanslik
Service de néphrologie, hôpital Ambroise-Paré, AP-HP, 92104 Boulogne-Billancourt cedex, France.
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Yattara
Service de néphrologie, hôpital Ambroise-Paré, AP-HP, 92104 Boulogne-Billancourt cedex, France.
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Ayari
Université Versailles Saint-Quentin-en-Yvelines, 78000 Versailles, France; Service de médecine interne, hôpital Ambroise-Paré, AP-HP, 92104 Boulogne-Billancourt cedex, France.
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Rouveix
Université Versailles Saint-Quentin-en-Yvelines, 78000 Versailles, France; Service de néphrologie, hôpital Ambroise-Paré, AP-HP, 92104 Boulogne-Billancourt cedex, France.
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Massy
Université Versailles Saint-Quentin-en-Yvelines, 78000 Versailles, France; Service de néphrologie, hôpital Ambroise-Paré, AP-HP, 92104 Boulogne-Billancourt cedex, France.
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Prinseau
D000138:Acidosis / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D000141:Acidosis, Renal Tubular / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D000328:Adult; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007008:Hypokalemia / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D008297:Male; D008875:Middle Aged
Acidose tubulaire distale; Acidose tubulaire proximale; Distal tubular renal acidosis; Nephrocalcinosis; Néphrocalcinose; Proximal tubular renal acidosis; Trou anionique urinaire; Urinary anionic gap