[Construction of analytical method for similarity of traditional Chinese medicine components on the basis of biopharmaceutic properties].
Traditional Chinese medicine components are a complex multi-component system. How to characterize and evaluate their diverse properties have long been key scientific problems in the modernization process of traditional Chinese medicines. According to the relevant regulations for biopharmaceutical properties, we made the criteria for evaluating similarity of Chinese medicine components, while establish an analytical method based on cosine and Grubbs to evaluate the dispersion degree of properties of representative components, so as to provide ideas and methods for classifying traditional Chinese medicine sub-components and evaluating the integrity of component properties.
Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China. xiaoyu9456@sina.com
Dan-Hong
DH
Yu
Xiao-Bin
XB
Jia
D004365:Drugs, Chinese Herbal / Q000032:analysis*; D008516:Medicine, Chinese Traditional; D012995:Solubility
D004365:Drugs, Chinese Herbal