Assessing Jasminum grandiflorum L. authenticity by HPLC-DAD-ESI/MS(n) and effects on physiological enzymes and oxidative species.
The dried flower buds of Jasminum grandiflorum L. are widely consumed as infusion and used in traditional medicine for psychiatric disorders. It is important to have a well-established method for the chemical characterization of J. grandiflorum since there are resemblances with a toxic species, Gelsemium sempervirens (L.) Jaume Saint-Hilaire. HPLC-DAD-ESI/MS(n) analysis allowed identifying six phenolic compounds for the first time. Moreover, the evaluation of in vitro activity against central nervous system (CNS) related enzymes was undertaken for the first time, as well as against reactive species in order to support the efficacy towards CNS disorders.
Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS (CSIC), P.O. Box 164, 30100 Campus University Espinardo, Murcia, Spain. Electronic address: federico@cebas.csic.es.
Federico
F
Ferreres
Clara
C
Grosso
Angel
A
Gil-Izquierdo
Patrícia
P
Valentão
Paula B
PB
Andrade
D000470:Alkaloids / Q000032:analysis; D000928:Antidepressive Agents / Q000032:analysis; D000975:Antioxidants / Q000032:analysis / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D002800:Cholinesterase Inhibitors / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D004791:Enzyme Inhibitors / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry; D035264:Flowers / Q000737:chemistry; D031660:Jasminum / Q000737:chemistry*; D008519:Medicine, Traditional; D008996:Monoamine Oxidase Inhibitors / Q000032:analysis; D010100:Oxygen / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry; D010936:Plant Extracts / Q000032:analysis*; D026361:Reactive Nitrogen Species / Q000737:chemistry; D017382:Reactive Oxygen Species / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
D000470:Alkaloids; D000928:Antidepressive Agents; D000975:Antioxidants; D002800:Cholinesterase Inhibitors; D004791:Enzyme Inhibitors; D005419:Flavonoids; D008996:Monoamine Oxidase Inhibitors; D010636:Phenols; D010936:Plant Extracts; D026361:Reactive Nitrogen Species; D017382:Reactive Oxygen Species; D010100:Oxygen
Cholinesterases; HPLC-DAD-ESI/MS(n); Jasminum grandiflorum L.; MAO-A; Oxidative species; Phenolic compounds