C-N bond forming cross-coupling reactions: an overview.
Nitrogen containing compounds are of great importance because of their interesting and diverse biological activities. The construction of the C-N bond is of significant importance as it opens avenues for the introduction of nitrogen in organic molecules. Despite significant advancements in this field, the construction of the C-N bond is still a major challenge for organic chemists, due to the involvement of harsh reaction conditions or the use of expensive catalysts in many cases. Thus, it is a challenge to develop alternative, milder and cheaper methodologies for the construction of C-N bonds. Herein, we have selected some prime literature reports that may serve this purpose.
Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), University of Leuven (KU Leuven), Department of Chemistry, Celestijnenlaan 200F, B-3001, Leuven, Belgium. Erik.VanderEycken@chem.kuleuven.be.
Jitender
J
Bariwal
Erik
E
Van der Eycken
D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D017672:Nitrogen Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D009930:Organic Chemicals / Q000138:chemical synthesis / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D028561:Transition Elements / Q000737:chemistry
D017672:Nitrogen Compounds; D009930:Organic Chemicals; D028561:Transition Elements; D010165:Palladium; D002244:Carbon; D003300:Copper