[Study on optimization of drying method and its mechanism in Ginkgo biloba leaves].
To provide a scientific evidence for the initial primary processing method, an ultra-high performance liquid chromatography combined with a triple quadrupole electrospray tandem mass spectrometry (UPLC-MS/MS) was used to analyze the contents variation of catechins, flavonoids, flavonoid glycosides, biflavones, terpene lactones and phenolic acids during the process of drying in the sun, in the shade, and baked with 35, 45, 60, 80 degrees C, respectively. The results show that drying in the 80 degrees C is conducive to the accumulation of catechins, flavonoid glycosides, terpene lactones, better than the effects of other procedures. Therefore, the fast drying at 80 degrees C is beneficial for the retention of various types of active ingredient of Ginkgo biloba, and this method could be applied as a preferably dry processing.
Nanjing University of Chinese Medicine, Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae, Nanjing 210046, China. ghlzyq@163.com
Han-Liang
HL
Guan
Da-Wei
DW
Qian
Jin-Ao
JA
Duan
Hao
H
Ren
Ye-Fei
YF
Qian
Yu-Ping
YP
Tang
Pei
P
Liu
D002851:Chromatography, High Pressure Liquid; D020441:Ginkgo biloba / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D053719:Tandem Mass Spectrometry; D013678:Technology, Pharmaceutical