Neonatal seizure as a manifestation of unrecognized maternal hyperparathyroidism.
Maternal hypercalcemia suppresses parathyroid activity in the fetus resulting in impaired parathyroid responsiveness to hypocalcemia after birth. Resultant hypocalcemia may be severe and prolonged and rarely may lead to convulsions. Here, we present a newborn infant admitted to the pediatric emergency department at age two weeks with recurrent tonic convulsions due to asymptomatic maternal hyperparathyroidism and vitamin D deficiency. Physicians should be aware that undiagnosed maternal hyperparathyroidism can cause severe hypocalcemia in the newborn.
Dr. Behçet Uz Children Disease and Surgery Training and Research Hospital, Department of Pediatric Endocrinology, İzmir, Turkey. E-mail: drkorkmazanil@hotmail.com.
Hüseyin Anıl
HA
Korkmaz
Behzat
B
Ozkan
Demet
D
Terek
Ceyhun
C
Dizdarer
Sertaç
S
Arslanoğlu
D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000150:complications*; D006961:Hyperparathyroidism / Q000150:complications*; D006996:Hypocalcemia / Q000150:complications* / Q000175:diagnosis; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology*; D008297:Male; D011247:Pregnancy; D012640:Seizures / Q000209:etiology; D014808:Vitamin D Deficiency / Q000150:complications; D055815:Young Adult