Long-term hearing outcome after retrosigmoid removal of vestibular schwannoma.
Although many investigators have reported the hearing function in the immediate postoperative period in patients with vestibular schwannoma (VS), little is known about the long-term outcomes of the postoperative hearing. The aim of this study was to analyze the long-term hearing outcomes at a mean follow-up of 5 years in patients with unilateral VS treated via the retrosigmoid approach. Twenty-four patients with immediate postoperative serviceable hearing who underwent repeated audiogram or phone interview were included in this study. During the mean follow-up period (68.8 ± 30.2 months, range 14-123 months), serviceable hearing was preserved in 20 out of the 24 patients (83%). Pure tone average (PTA) was reevaluated within 6 months in seven patients. In the two patients whose PTA deteriorated ≥ 5 dB in 6 months after surgery, their PTA worsened ≥ 15 dB compared to the immediate postoperative PTA. In the remaining five patients whose PTA deteriorated < 5 dB in 6 months after surgery, PTA was maintained within a 15-dB deterioration at the final follow-up (p = 0.04, Fisher's exact test). According to Kaplan-Meier survival plots, the 5-year or 7-year preservation rate of serviceable hearing was 86.2% or 71.8%, respectively. Further study will be needed to clarify the mechanism underlying the long-term decline of serviceable hearing; however, the deterioration of PTA in the early postoperative period may help to predict the long-term outcomes of hearing.
Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University.
Akira
A
Nakamizo
Megumu
M
Mori
Daisuke
D
Inoue
Toshiyuki
T
Amano
Masahiro
M
Mizoguchi
Koji
K
Yoshimoto
Tomio
T
Sasaki
D000328:Adult; D001301:Audiometry, Pure-Tone; D003392:Cranial Sinuses; D005260:Female; D005500:Follow-Up Studies; D006319:Hearing Loss, Sensorineural / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D046088:Hearing Loss, Unilateral / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000150:complications / Q000601:surgery*; D059351:Organ Sparing Treatments; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D011930:Reaction Time; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult