Skeletal alterations in women affected by obesity.
Obesity has always been considered a protective factor for the skeleton and for osteoporosis. However, new epidemiologic and clinical data have shown that high level of fat mass might be a risk factor for osteoporosis and fragility fractures. Further, increasing evidences seem to indicate that the different components of metabolic syndrome (i.e. hypertension, increased triglycerides, and reduced high-density lipoprotein cholesterol) are also potential risk factors for the development of low bone mineral density and osteoporosis.
Unit of Endocrinology, Department of Movement, Human and Health Sciences, University "Foro Italico" of Rome, Largo de Bosis 14, 00135, Rome, Italy, migliacciosilvia@hotmail.it.
Silvia
S
Migliaccio
Emanuela A
EA
Greco
Rachele
R
Fornari
Lorenzo M
LM
Donini
Luigi
L
Di Luigi
Andrea
A
Lenzi
D015519:Bone Density; D001847:Bone Diseases / Q000150:complications* / Q000378:metabolism; D001842:Bone and Bones / Q000378:metabolism / Q000503:physiopathology; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D007249:Inflammation; D007333:Insulin Resistance; D024821:Metabolic Syndrome / Q000150:complications* / Q000378:metabolism; D009765:Obesity / Q000150:complications* / Q000378:metabolism; D015675:Osteocalcin / Q000378:metabolism; D010024:Osteoporosis / Q000150:complications*; D017698:Postmenopause; D012307:Risk Factors; D014807:Vitamin D / Q000378:metabolism
D015675:Osteocalcin; D014807:Vitamin D