n-BuLi/LiCH2CN-mediated one-carbon homologation of aryl epoxides into conjugated allyl alcohols.
A series of styrene oxides in the presence of a 1:1 mixture of n-butyllithium (n-BuLi) and lithioacetonitrile (LiCH2CN) in THF are converted into one-carbon homologated allyl alcohols in an unusual regioselective manner.
Department of Chemistry and Biochemistry, University of Mississippi , University, Mississippi 38677, United States.
Takashi
T
Tomioka
Rambabu
R
Sankranti
Tsuyoshi
T
Yamada
Courtney
C
Clark