Evaluation of biopsy methods in the diagnosis of submandibular space pathology.
The aim of this study was to evaluate the performance of fine needle aspiration cytology (FNAC), ultrasound-guided core needle biopsy (USCNB), punch biopsy, and surgical excision biopsy in neoplasms presenting within the submandibular space. A retrospective analysis of all patients with a pathological diagnosis of a submandibular space neoplasm within a 12-year period (February 1999 to June 2011) was performed. Biopsy results were compared to histopathological diagnosis obtained from surgical excision biopsy. Eighty-one specimens from 44 patients met the search criteria (15 FNAC, 24 USCNB, 7 punch biopsy, and 35 surgical excision biopsy). The final diagnosis was established by USCNB, punch biopsy, or surgical excision biopsy and not by FNAC alone. Surgical excision biopsy was performed as a primary diagnostic (n = 8), secondary diagnostic (n = 15), or as a post-diagnostic therapeutic procedure (n = 12). Non-diagnostic results were: FNAC 11/15, USCNB 2/24, and punch biopsy 1/7. Diagnostic results were: FNAC 2/15, USCNB 20/24, and punch biopsy 5/7. No complications were reported. Although punch biopsy demonstrated good yield and accuracy, its use is restricted to a small cohort of patients. USCNB is a safe and accurate technique in the submandibular space, with a low non-diagnostic rate.
Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK. Electronic address: jide.olubaniyi@nhs.net.
B O
BO
Olubaniyi
Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK.
V
V
Chow
Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK.
U
U
Mandalia
Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK.
S
S
Haldar
Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK.
G
G
Gok
Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK.
P
P
Michl
Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK.
K
K
Ramesar
Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK.
E
E
Sellon
Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK.
M
M
Williams
Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK.
D C
DC
Howlett
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy / Q000379:methods*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013365:Submandibular Gland Neoplasms / Q000473:pathology*; D018084:Ultrasonography, Interventional
fine needle aspiration cytology; punch biopsy; salivary gland; submandibular gland; surgical excision biopsy; ultrasound-guided core needle biopsy