μ-Synthesis of dissimilation process of glycerol to 1,3-propanediol in microbial continuous culture.
In this paper, robust control problem using μ-synthesis in microbial continuous culture is studied. The dissimilation process of glycerol to 1,3-propanediol cannot avoid the disturbances caused by uncertain factors. Based on the biodynamical model, a control system with the initial glycerol concentration as input control is proposed to simplify the controller design. μ-synthesis method is applied to find a feedback controller to assure both of robust stability and robust performance of the closed-loop system simultaneously. To solve the corresponding structured singular value optimization problem, a converged result is obtained through D-K iteration method. The μ-synthesis system is also compared with the corresponding H(∞) system. The simulation results indicate that the μ-controller might be more feasible for the continuous bioprocess controlling.
Xi
X
Zhu
Jinlong
J
Yuan
Xinying
X
Wang
Enmin
E
Feng
Zhilong
Z
Xiu
D001711:Biotransformation; D005285:Fermentation; D005990:Glycerol / Q000378:metabolism*; D007711:Klebsiella pneumoniae / Q000254:growth & development / Q000378:metabolism*; D008962:Models, Theoretical; D011409:Propylene Glycols / Q000378:metabolism*
D011409:Propylene Glycols; C041787:1,3-propanediol; D005990:Glycerol