An efficient and cost-effective preparation of di-O-acetyl-D-rhamnal.
We have developed a synthetic route to the frequently utilized deoxysugar building block di-O-acetyl-D-rhamnal originating from the inexpensive starting material methyl α-D-glucopyranoside. Our approach proceeds in five steps with minimal column chromatography purification needed to afford the title compound in good overall yield. 2009 Elsevier Ltd. All rights reserved.
Department of Chemistry, Sewanee: The University of the South, 735 University Avenue, Sewanee, TN 37383-1000, USA.
Justin N
JN
Miller
Rongson
R
Pongdee
carbohydrates; deoxysugars; glycosides; natural products