Diels-alder reactions of styrylcyclohexenones: an efficient procedure for the synthesis of substituted dehydrodecaline derivatives.
The Diels-Alder reaction of styrylcyclohex-2-enone derivatives 1 with N-phenylmaleimide was shown to be an efficient pathway for the synthesis of substituted dehydrodecaline derivatives. At elevated temperatures, mixtures of endo/exo adducts were formed, while in the presence of TiCl4 exclusive formation of the endo stereoisomer was observed. Spectroscopic analysis and X-ray crystallography confirmed the formation of the endo adducts.
M Saeed
MS
Abaee
Mohammad M
MM
Mojtahedi
M Taghi
MT
Rezaei
Hamid Reza
HR
Khavasi