Bifunctional primary amine-thioureas in asymmetric organocatalysis.
Research disclosed since the demonstration of the first examples of primary amine-thiourea organocatalysis in 2006 has shown that primary amine-based thioureas can successfully catalyze a diverse variety of highly enantioselective transformations providing a wide range of versatile organic compounds. Recent remarkable progress with these chiral catalysts is summarized in this review.
Department of Chemistry and Pharmacy, Institute of Organic Chemistry 1, University of Erlangen-Nuremberg, Henkestrasse 42, 91054 Erlangen, Germany. tsogoeva@chemie.uni-erlangen.de.
Olga V
OV
Serdyuk
Christina M
CM
Heckel
Svetlana B
SB
Tsogoeva