Synthetic studies toward the citrinadin A and B core architecture.
The core architecture of the citrinadin alkaloids has been prepared in racemic form by utilizing a strategy that exploits the alkylation of 2-methoxypyridines. An initially planned indolizidine to quinolizidine transformation to build the D/E rings was unsuccessful. Success was ultimately gained by a direct alkylation to establish the citrinadin core architecture.
Department of Chemistry, University of California , Berkeley, California 94720, United States.
Devon A
DA
Mundal
Richmond
R
Sarpong
D000478:Alkylation; D026121:Indole Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism
D026121:Indole Alkaloids; D011725:Pyridines; C503673:citrinadin A