[Pigment dispersion syndrome and pigmentary glaucoma. Morphometric analysis of the anterior chamber segment with SL-OCT].
BACKGROUND
The purpose of this study was to analyze if anterior chamber parameters are risk factors for the development of pigment dispersion syndrome (PDS) and/or for the conversion to pigmentary glaucoma (PG).


METHODS
This study included a total of 63 eyes from 35 patients with PDS and PG and 65 eyes from 49 unaffected volunteers as the control group. The following parameters were measured by slit lamp optical coherence tomography (SL-OCT): anterior chamber volume (ACV) and depth (ACD), angle opening distance (AOD) and the trabecular iris space area (TISA) at 500 µm and 750 μm from the scleral spur. Comparisons between the following groups were performed: between the PDS/PG and the control group, between PDS and PG and between male and female patients.


RESULTS
The results of ACV, ACD, AOD and TISA were significantly higher in PDS/PG patients when compared to the control group. There were no significant differences between PDS and PG. The gender-specific comparison also showed no significant differences.


CONCLUSIONS
Significantly higher anterior chamber parameters are a possible risk factor for development of PDS; however, a higher risk of conversion to PG does not seem to correlate with increased anterior chamber parameters. The parameters of the anterior chamber are apparently not associated with the male predominance of PDS and PG.
Augenklinik, Friedrich-Alexander Universität Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Deutschland.
B
B
Birner
T
T
Tourtas
J M
JM
Wessel
A G
AG
Jünemann
C Y
CY
Mardin
F E
FE
Kruse
R
R
Laemmer
D000328:Adult; D000368:Aged; D000869:Anterior Eye Segment / Q000473:pathology*; D017889:Exfoliation Syndrome / Q000150:complications* / Q000473:pathology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012307:Risk Factors; D012680:Sensitivity and Specificity; D012737:Sex Factors; D066167:Slit Lamp; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*