Meningoencephalitis due to Gemella haemolysans.
Gemella haemolysans is an uncommon but described cause of invasive disease in humans. We report a case of meningitis due to G. haemolysans that did not grow in cerebrospinal fluid culture, demonstrating a potential role for direct 16S rRNA gene PCR and sequencing in culture-negative cerebrospinal fluid when bacterial meningitis is suspected.
Department of Internal Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
Benjamin T
BT
Galen
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
David B
DB
Banach
Pathology and Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.
Melissa R
MR
Gitman
Section of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA.
Terence K
TK
Trow
D000368:Aged; D001431:Bacteriological Techniques; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D058834:Gemella / Q000302:isolation & purification*; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D008853:Microscopy; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA
D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S