Treatment of anterior vaginal wall prolapse with and without polypropylene mesh: a prospective, randomized and controlled trial - Part I.
OBJECTIVE
To compare the use of polypropylene mesh (PM) and the traditional anterior vaginal wall colporraphy in women with anterior vaginal wall prolapse (AVWP) using objective and subjective tests and evaluation of quality of life (QoL).


METHODS
One hundred women were randomly distributed in two preoperatory groups. The first group (mesh) (n = 45) received a PM implant and the control group (n = 55) was submitted to traditional colporraphy. Postoperatory follow-up was done after 12 months. The primary objective was the correction of the Ba point ≤ -2 POP-Q (Pelvic Organ Prolapse Quantification System) and the secondary objective was the improvement of vaginal symptoms and QoL through ICIQ-VS (International Consultation on Incontinence Questionnaire - Vaginal Symptoms). Complications related to the use of PM or not were also described.


RESULTS
There was a significant difference between all POP-Q measures of pre- and postoperatory periods of each group in particular. There was a significant difference of the Ba point of the postoperatory period between the Mesh and Control group. The mean of Ba point in the Mesh group was statistically lower than of the Control group, depicting the better anatomical result of the first group. Both techniques improved vaginal symptoms and QoL. The most frequent complication of the Mesh group was prepubic hematoma in the perioperative period. In 9.3% of the cases treated with mesh it was observed PM exposition at the anterior vaginal wall after 12 months, being most of them treated clinically.


CONCLUSIONS
The treatment of AVWP significantly improved the Ba point in the Mesh group in comparison to the Control group. There were no differences of the vaginal symptoms and QoL between the two groups after 12 months. There were few and low grade complications on both groups.
Department of Medicine, Federal University of Sao Carlos, Sao Carlos, SP, Brazil.
José Tadeu Nunes
JT
Tamanini
Mirce Milhomem da Mota
MM
Tamanini
Renata Cristina de Oliveira Souza
RC
Castro
Paulo Cezar
PC
Feldner
Rodrigo de Aquino
Rde A
Castro
Marair Gracio Ferreira
MG
Sartori
Manoel João Batista Castello
MJ
Girão
D000368:Aged; D000369:Aged, 80 and over; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000534:rehabilitation / Q000601:surgery*; D008875:Middle Aged; D011126:Polypropylenes / Q000627:therapeutic use*; D011446:Prospective Studies; D011788:Quality of Life; D012016:Reference Values; D016037:Single-Blind Method; D013526:Surgical Mesh; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000534:rehabilitation / Q000601:surgery; D014596:Uterine Prolapse / Q000534:rehabilitation / Q000601:surgery*
D011126:Polypropylenes