INVEX--a web-based tool for integrative visualization of expression data.
CONCLUSIONS
Gene expression or metabolomics data generated from clinical settings are often associated with multiple metadata (i.e. diagnosis, genotype, gender, etc.). It is of great interest to analyze and to visualize the data in these contexts. Here, we introduce INVEX-a novel web-based tool that integrates the server-side capabilities for data analysis with the browse-based technology for data visualization. INVEX has two key features: (i) flexible differential expression analysis for a wide variety of experimental designs; and (ii) interactive visualization within the context of metadata and biological annotations. INVEX has built-in support for gene/metabolite annotation and a fully functional heatmap builder.


METHODS
Freely available at http://www.invex.ca.
Department of Microbiology and Immunology, University of British Columbia, Vancouver, Canada V6T 1Z3, Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, Canada V6T 1Z4 and Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Jianguo
J
Xia
Ngan H
NH
Lyle
Matthew L
ML
Mayer
Olga M
OM
Pena
Robert E W
RE
Hancock
D000818:Animals; D003196:Computer Graphics; D020869:Gene Expression Profiling; D006801:Humans; D020407:Internet; D055432:Metabolomics; D058977:Molecular Sequence Annotation; D012984:Software; D014584:User-Computer Interface