Synthesis and activity of novel acylthiourea with hydantoin.
The 41 novel acylthiourea derivatives with hydantoin were synthesized in moderate to excellent yields by using 5-(4-aminophenyl)- and 5-(4-aminobenzyl)-hydantoin or 5-(4-aminobenzyl)-thiohydantoin as raw materials and characterized by IR, 1H NMR spectra and elementary analysis. The preliminary bioassay showed that these compounds exhibit certain selectively herbicidal activities with the 91%, 94% and 87% inhibition rates of 7l, 8o and 8p against B. campestris, 100%, 100% and 95% efficacy against B. campestris in a greenhouse test, respectively. 7a, 7b, 7c and 7d exhibited 74%, 79%, 79% and 71% inhibition rates against F. oxysporum, respectively.
Department of Applied Chemistry, China Agricultural University, Beijing 100193, China. wangma@cau.edu.cn.
Jintao
J
Han
Hongbo
H
Dong
Zhihong
Z
Xu
Jinmin
J
Wang
Mingan
M
Wang
D006540:Herbicides / Q000737:chemistry* / Q000494:pharmacology*; D006827:Hydantoins / Q000737:chemistry* / Q000494:pharmacology*
D006540:Herbicides; D006827:Hydantoins