Calciphylaxis treated with sodium thiosulfate: report of two cases.
Although traditionally observed in patients with end-stage renal disease and secondary hyperparathyroidism, calciphylaxis has been reported in patients with normal renal and parathyroid function. There is no evidence-based therapy available. The use of sodium thiosulfate (STS) has been increasingly described. Herein we describe two patients who responded well to this treatment.
Complexo Hospitalario de Pontevedra.
Celia Posada
CP
Garcia
Elena
E
Roson
Gonzalo
G
Peon
Maria Teresa
MT
Abalde
Carlos
C
De La Torre
D000074:Acenocoumarol / Q000009:adverse effects / Q000627:therapeutic use; D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000188:drug therapy / Q000453:epidemiology; D002115:Calciphylaxis / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D057915:Drug Substitution; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications; D054068:Livedo Reticularis / Q000453:epidemiology; D009765:Obesity / Q000453:epidemiology; D016491:Peripheral Vascular Diseases / Q000453:epidemiology; D012307:Risk Factors; D012772:Shock, Septic / Q000209:etiology; D013885:Thiosulfates / Q000494:pharmacology / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000150:complications; D014808:Vitamin D Deficiency / Q000150:complications
D006495:Heparin, Low-Molecular-Weight; D013885:Thiosulfates; C017717:sodium thiosulfate; D000074:Acenocoumarol