A strategy for addressing aspirin hypersensitivity in patients requiring urgent PCI.
Aspirin is key to the treatment of acute myocardial infarction, particularly if stent implantation is considered. In patients with a history of hypersensitivity to aspirin, the optimal management of ST-segment elevation acute myocardial infarction is unclear. We suggest a strategy for addressing this problem by performing percutaneous coronary intervention with antiplatelet therapy by intravenous glycoprotein IIb/IIIa receptor blockers and performing rapid oral desensitization in the ensuing hours, once the patient has stabilized.
Hôpital d'Instruction des Armées du Val de Grâce, Paris, France.
Patrick
P
Schiano
Philippe Gabriel
PG
Steg
Franck
F
Barbou
Jacques
J
Monségu
Acute myocardial infarction; allergy; aspirin; desensitisation