Marine-Lenhart syndrome in a young girl.
Graves' disease is the most common reason of hyperthyroidism in children. Graves' disease with accompanying functioning nodules is defined as Marine-Lenhart syndrome. This syndrome has not been described in children before. Here, a 15-year-old girl with Graves' disease and a coexisting cold nodule is presented. A thyroid scan showed diffuse uptake of Tc-99m pertechnatate in both lobes and decreased uptake in accordance with the left lobe nodule. The nodule was histologically diagnosed as benign. The patient was diagnosed with type 1 diabetes mellitus and polyglandular autoimmune syndrome during clinical follow-up. The differential diagnoses of Graves' disease with coexisting nodules should include the Marine-Lenhart syndrome. Treatment options should be determined taking this rare condition into account.
Yaşar
Y
Şen
Emine Ayça
EA
Cimbek
Sevil Arı
SA
Yuca
Gonca Kara
GK
Gedik
Oktay
O
Sarı
D000293:Adolescent; D013956:Antithyroid Agents / Q000627:therapeutic use; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D005260:Female; D006111:Graves Disease / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008713:Methimazole / Q000627:therapeutic use; D016884:Polyendocrinopathies, Autoimmune / Q000150:complications; D013577:Syndrome
D013956:Antithyroid Agents; D007457:Iodine Radioisotopes; D008713:Methimazole