Fatal outcome of rhino-orbital-cerebral mucormycosis due to bilateral internal carotid occlusion in a child after hematopoietic stem cell transplantation.
Rhino-orbito-cerebral mucormycosis is a rare fulminant opportunistic fungal infection that particularly occurs in immunocompromised patients. We present a case of fatal invasive rhino-orbito-cerebral mucormycosis complicated by bilateral thrombotic occlusion of the internal carotid artery with consequent cerebral infarction in a 5-year-old boy after hematopoietic stem cell transplantation for acute pre-B-cell lymphoblastic leukemia.
From the Departments of *Neurology, †Diagnostic Imaging and ‡Immunology, University Children's Hospital of Zurich, Zurich, Switzerland.
Lucia
L
Abela
Sandra P
SP
Toelle
Annette
A
Hackenberg
Ianina
I
Scheer
Tayfun
T
Güngör
Barbara
B
Plecko
D001927:Brain Diseases / Q000382:microbiology / Q000473:pathology*; D002341:Carotid Artery Thrombosis / Q000473:pathology*; D002675:Child, Preschool; D017809:Fatal Outcome; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009091:Mucormycosis / Q000473:pathology*; D009668:Nose Diseases / Q000382:microbiology / Q000473:pathology; D009894:Opportunistic Infections / Q000382:microbiology / Q000473:pathology*; D009916:Orbital Diseases / Q000382:microbiology / Q000473:pathology; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000601:surgery