Erasmus syndrome: silicosis and systemic sclerosis.
The silicosis is the pneumoconiosis more frequent, resulting from the inhalation of silica or silicates containing mineral dust, mainly characterized by irreversible lung fibrosis. It is associated with the development of other diseases, including pulmonary tuberculosis, lung cancer and autoimmune diseases. The connective tissue disease after exposure to silica occurs usually after 15 years of initial exposure.The Erasmus syndrome describes the association of systemic sclerosis following exposure to silica with or without silicosis. The authors report two cases of patients with diagnosis of silicosis who developed systemic sclerosis.
Aryádine Allinne Machado
AA
de Miranda
Alice Carvalho
AC
Nascimento
Isy Lima
IL
Peixoto
Juliana Alves
JA
Scrignoli
Maria do Socorro de Lucena
Mdo S
Cardoso
Sandra Lúcia Euzébio
SL
Ribeiro
D000328:Adult; D006801:Humans; D008297:Male; D012595:Scleroderma, Systemic / Q000175:diagnosis / Q000209:etiology; D012829:Silicosis / Q000150:complications / Q000175:diagnosis; D013577:Syndrome