Gold(I)-catalyzed formation of furans from γ-acyloxyalkynyl ketones.
Various γ-acyloxyalkynyl ketones were efficiently converted into highly substituted furans with 2.5 mol % of triflimide (triphenylphosphine)gold(I) as a catalyst in dichloroethane at 70 °C.
Laboratoire de Synthèse, Réactivité Organiques et Catalyse, Institut de Chimie, UMR 7177 associé au CNRS, Université de Strasbourg, 4 rue Blaise Pascal, 67070 Strasbourg, France.
Marie
M
Hoffmann
Solène
S
Miaskiewicz
Jean-Marc
JM
Weibel
Patrick
P
Pale
Aurélien
A
Blanc
1,2-migration; alkynyl ketones; cycloisomerization; furans; gold-catalysis