Tobacco treatment outcomes in patients with and without a history of depression, Czech Republic, 2005-2010.
BACKGROUND
Higher prevalence of smoking among depressed patients, as well as the risk of depression in smokers, is well documented. The proportion of patients with a history of depression among those seeking intensive treatment of tobacco dependence is also high. In contrast, evidence of treatment success in this subgroup of patients is controversial. The aim of this study was to compare smoking abstinence rates after tobacco treatment in smokers with and without a history of depression.


METHODS
We reviewed retrospective data from 1,730 smokers seeking treatment in Prague, Czech Republic. History of depression was defined as past diagnosis of depression or current treatment of depression. After a 1-year, self-reported smoking status was validated by expired-air carbon monoxide. We used logistic regression to analyze associations between abstinence rates, history of depression, and other factors (eg, age, sex, tobacco dependence).


RESULTS
Of 1,730 smokers treated, 289 (16.7%) had a history of depression. The smoking abstinence rate at 1 year was 32.5% for smokers with a history of depression and 38.7% for those with no history (P = .048). Among women, abstinence did not differ between groups (35.0% vs 35.7%; P = .86). However, among men, those with a history of depression had lower rates of abstinence (27.4% vs 41.3%; P = .009). After adjustment for baseline covariates, history of depression was not significantly associated with smoking abstinence in men or women.


CONCLUSIONS
Intensive outpatient tobacco treatment programs can achieve abstinence rates among smokers with a history of depression similar to rates among the general population.
The 3rd Medical Department, and Institute of Hygiene and Epidemiology, First Faculty of Medicine and General University Hospital, Charles University in Prague, Czech Republic.
Lenka
L
Stepankova
Eva
E
Kralikova
Kamila
K
Zvolska
Alexandra
A
Kmetova
Milan
M
Blaha
Zbynek
Z
Bortlicek
Michal
M
Sticha
Martin
M
Anders
Darrell R
DR
Schroeder
Ivana T
IT
Croghan
D018153:Czech Republic / Q000453:epidemiology; D003863:Depression / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012907:Smoking / Q000453:epidemiology*; D016540:Smoking Cessation / Q000379:methods*; D014029:Tobacco Use Disorder / Q000209:etiology* / Q000628:therapy; D016896:Treatment Outcome