Plant pararetroviruses: interactions of cauliflower mosaic virus with plants and insects.
Virion associated protein (VAP) binds to the icosahedral capsid of cauliflower mosaic virus (CaMV) - a plant pararetrovirus. The interactive coiled-coil domains of this protein can interact with the coiled-coils of either the movement protein or the aphid transmission factor, thereby mediating both cell-to-cell movement and aphid transmission. The host counters CaMV infection with two lines of defense: innate immunity and silencing. The viral protein 'transactivator/viroplasmin' (TAV) is recognized as an effector and either initiates the innate immunity reaction in a non-permissive host or interferes with it in a permissive host. As a silencing suppressor, TAV interferes with dicing of dsRNAs.
Basel University, Botanical Institute, Basel, Switzerland. Electronic address: hohn@fmi.ch.
Thomas
T
Hohn
D000818:Animals; D017796:Caulimovirus / Q000502:physiology*; D054884:Host-Pathogen Interactions; D007313:Insecta / Q000821:virology*; D010944:Plants / Q000821:virology*; D011485:Protein Binding; D014764:Viral Proteins / Q000378:metabolism; D053585:Virus Attachment
D014764:Viral Proteins