An epidemiological investigation of Campylobacter in pig and poultry farms in the Mekong delta of Vietnam.
Campylobacter are zoonotic pathogens commonly associated with gastroenteritis. To assess the relevance of Campylobacter in Vietnam, an economically transitioning country in SE Asia, we conducted a survey of 343 pig and poultry farms in the Mekong delta, a region characterized by mixed species farming with limited biosecurity. The animal-level prevalence of Campylobacter was 31·9%, 23·9% and 53·7% for chickens, ducks and pigs, respectively. C. jejuni was predominant in all three host species, with the highest prevalence in pigs in high-density production areas. Campylobacter isolates demonstrated high levels of antimicrobial resistance (21% and 100% resistance against ciprofloxacin and erythromycin, respectively). Multilocus sequence type genotyping showed a high level of genetic diversity within C. jejuni, and predicted C. coli inter-species transmission. We suggest that on-going intensification of animal production systems, limited biosecurity, and increased urbanization in Vietnam is likely to result in Campylobacter becoming an increasingly significant cause of human diarrhoeal infections in coming years.
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
J J
JJ
Carrique-Mas
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
J E
JE
Bryant
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
N V
NV
Cuong
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
N V M
NV
Hoang
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
J
J
Campbell
Sub-Department of Animal Health, Dong Thap Province,Vietnam.
N V
NV
Hoang
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
T T N
TT
Dung
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
D T
DT
Duy
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
N T
NT
Hoa
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
C
C
Thompson
Sub-Department of Animal Health, Dong Thap Province,Vietnam.
V V
VV
Hien
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
V V
VV
Phat
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
J
J
Farrar
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme,Oxford University Clinical Research Unit,Ho Chi Minh City,Vietnam.
S
S
Baker
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002167:Campylobacter / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification; D002169:Campylobacter Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D003430:Cross-Sectional Studies; D024881:Drug Resistance, Bacterial; D005243:Feces / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D058885:Multilocus Sequence Typing; D011200:Poultry; D011201:Poultry Diseases / Q000453:epidemiology* / Q000382:microbiology; D015995:Prevalence; D012307:Risk Factors; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology* / Q000382:microbiology; D014744:Vietnam / Q000453:epidemiology
D000900:Anti-Bacterial Agents