Effectiveness of diaphragmatic stimulation with single-channel electrodes in rabbits.
Every year, a large number of individuals become dependent on mechanical ventilation because of a loss of diaphragm function. The most common causes are cervical spinal trauma and neuromuscular diseases. We have developed an experimental model to evaluate the performance of electrical stimulation of the diaphragm in rabbits using single-channel electrodes implanted directly into the muscle. Various current intensities (10, 16, 20, and 26 mA) produced tidal volumes above the baseline value, showing that this model is effective for the study of diaphragm performance at different levels of electrical stimulation.
Federal University of Rio Grande do Sul, Porto Alegre Hospital de Clínicas, Porto Alegre, Brazil.
Rodrigo Guellner
RG
Ghedini
Julio de Oliveira
Jde O
Espinel
Elaine Aparecida
EA
Felix
Artur de Oliveira
Ade O
Paludo
Rodrigo
R
Mariano
Arthur Rodrigo Ronconi
AR
Holand
Cristiano Feijó
CF
Andrade
D000818:Animals; D003964:Diaphragm / Q000503:physiopathology*; D004195:Disease Models, Animal; D004558:Electric Stimulation / Q000295:instrumentation / Q000379:methods*; D004567:Electrodes, Implanted; D005260:Female; D010791:Phrenic Nerve / Q000503:physiopathology*; D011817:Rabbits; D015203:Reproducibility of Results; D012121:Respiration, Artificial