Investigation of the relation between anaerobic bacteria genus clostridium and late-onset autism etiology in children.
The aim of this study was to investigate the relation between the etiology of late-onset childhood autism and anaerobic bacteria. Thirty children diagnosed with autistic disorder and control group have been included in the study. 3-(3-hydroxy phenyl)-3-hydroxypropionic acid (HPHPA) excretion rates which is a metabolic product of the genus Clostridium, were measured via mass spectrometry-gas chromatography (MS-GC) method from urine samples. When the assayed average HPHPA values compared with each group, a statistically significant difference was found (p < 0.05). Data obtained from this study support the existence of a significant correlation between autism etiology and anaerobic bacteria.
a Department of Microbiology , Konya Education and Research Hospital , Konya , Trukey.
Recep
R
Keşli
Cem
C
Gökçen
Ufuk
U
Buluğ
Yüksel
Y
Terzi
D000293:Adolescent; D017668:Age of Onset; D000693:Anaerobiosis; D001321:Autistic Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology / Q000652:urine; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003013:Clostridium / Q000378:metabolism* / Q000472:pathogenicity; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008297:Male; D010666:Phenylpropionates / Q000652:urine; D014421:Turkey / Q000453:epidemiology
D010666:Phenylpropionates; C041797:3-(3-hydroxyphenyl)-3-hydroxypropanoic acid