Elastographic presentation of medullary thyroid carcinoma.
Aim of the study was to evaluate the elastographic appearance of medullary thyroid carcinoma (MTC) by a retrospective evaluation of 18 nodules histologically proven as MTC. Free-hand qualitative elastography was performed using Hitachi Logos EUB 7500. The elasticity score (ES), was assessed based on a colour elastogram, the blue colour being correlated with hard tissue, red colour with soft tissue, and green with intermediate hardness. Nodules were classified into four classes. A alleged diagnosis of malignancy was assigned to nodules with ES3 or 4 and a presumptive diagnosis of benignity was assigned to nodules with an ES1 or 2. More than half (55.6 %) of MTCs have a low-intermediate grade of elasticity. The hardest lesions (ES4) were those with ultrasonographic features highly suspicious for malignancy. In conclusion, most of MTCs present an elastographic pattern of benignity. Therefore, qualitative elastography does not add useful information in pointing out MTC on the basis of its hardness. Our data suggest a marginal role for this technique in MTC evaluation.
Division of Endocrine and Metabolic Diseases, Ospedale San Luca, IRCCS, Istituto Auxologico Italiano, p.le Brescia 20, 20149, Milan, Italy, massimoandrioli1@virgilio.it.
Massimiliano
M
Andrioli
Pierpaolo
P
Trimboli
Stefano
S
Amendola
Stefano
S
Valabrega
Nobuhiro
N
Fukunari
Moro
M
Mirella
Luca
L
Persani
D018278:Carcinoma, Neuroendocrine; D003937:Diagnosis, Differential; D054459:Elasticity Imaging Techniques; D006801:Humans; D009367:Neoplasm Staging; D012107:Research Design; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging*; D016606:Thyroid Nodule / Q000000981:diagnostic imaging