Detecting Sex-Biased Gene Flow in African-Americans through the Analysis of Intra- and Inter-Population Variation at Mitochondrial DNA and Y- Chromosome Microsatellites.
This study reports on variations at the mitochondrial DNA (mtDNA) hypervariable region 1 (HVR-1) and at seven Y-chromosome microsatellites in an African-American population sample from Chicago, IL, USA. Our results support the hypothesis that the population studied had undergone a European male-biased gene flow. We show that comparisons of intra-and inter-population diversity parameters between African-Americans, Europeans and Africans may help detect sex-biased gene flow, providing a complement to quantitative methods to estimate genetic admixture.
Dipartimento di Biologia Ambientale, Università "La Sapienza", Roma, Italia.
C
C
Battaggia
P
P
Anagnostou
I
I
Bosch
F
F
Brisighelli
G
G
Destro-Bisol
M
M
Capocasa
Admixture; African-Americans; Mitochondrial DNA (mtDNA); Sex-biased gene flow; Y-chromosome