Laparoscopic versus open liver resection for benign and malignant solid liver tumors: a case-matched study.
BACKGROUND
Laparoscopic liver resection (LLR) is proposed as an alternative to open liver resection (OLR) for treatment of liver tumors. The aim of this study was to compare the surgical and oncological outcomes of LLR versus OLR in benign and malignant solid liver tumors.


METHODS
In this case-matched study, charts of 497 patients with liver lesions who had LLR or OLR in our center were retrospectively reviewed. Among them, 54 consecutive patients with benign or malignant solid liver tumors who had LLR were matched with a similar number of patients with OLR based on the pathology and extent of liver resection. Additionally, the surgical and oncological outcomes such as operating room time, amount of blood transfusion requirement, free resection margin rate, length of hospital stay, complication rate, perioperative mortality, and survival were compared between the two groups.


RESULTS
Demographics, pathological characteristics of the tumor, and extent of liver resection were similar between the two groups. Twenty-nine (54%) patients in each group had malignant lesions. There were no statistically significant differences between the two groups in terms of operating room time, amount of blood transfusion requirement, free resection margin, or postoperative complication rate or survival. However, hospital stay was significantly shorter in the laparoscopic group (5.9 versus 9 days, P=.006). Although no perioperative mortality was observed in patients with benign tumors, among the patients with malignant tumors, 2 died perioperatively in each group.


CONCLUSIONS
Our results in accordance with previous studies demonstrated that although the oncological outcomes of LLR and OLR were comparable, LLR patients had a shorter hospital stay.
1 John C. McDonald Regional Transplant and Hepatopancreatobiliary Surgery Center , Willis-Knighton Health System, Shreveport, Louisiana.
Mohammad Kazem
MK
Fallahzadeh
Gazi B
GB
Zibari
Alireza
A
Hamidian Jahromi
Quyen
Q
Chu
Runhua
R
Shi
Hosein
H
Shokouh-Amiri
D000236:Adenoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D000368:Aged; D002277:Carcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000401:mortality / Q000473:pathology / Q000601:surgery; D006222:Hamartoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D006391:Hemangioma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D006498:Hepatectomy; D006801:Humans; D010535:Laparoscopy; D007902:Length of Stay; D008113:Liver Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000401:mortality / Q000473:pathology / Q000601:surgery; D061646:Operative Time; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome