Sex-specific association of the ST8SIAII gene with schizophrenia in a Spanish population.
We investigated the association between ST8SIAII and schizophrenia in a sample of Spanish origin. We found that the G allele (P=0.044) and the AG genotype (P=0.040) of rs3759916 were associated in females. The ACAG haplotype (rs3759914, rs3759915, rs3759916 and rs2305561) was associated in males (P=0.028).
Genetics Department, Faculty of Biological Sciences, University of Valencia, Spain; Neurobiology Unit and Program in Basic and Applied Neurosciences, Department of Cell Biology, University of Valencia, Spain; CIBERSAM, Spain; INCLIVA, Valencia, Spain.
Javier
J
Gilabert-Juan
Juan
J
Nacher
Julio
J
Sanjuán
María Dolores
MD
Moltó
D000483:Alleles; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005838:Genotype; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D008297:Male; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D011401:Promoter Regions, Genetic / Q000235:genetics; D012559:Schizophrenia / Q000208:ethnology / Q000235:genetics*; D012737:Sex Factors; D012799:Sialyltransferases / Q000235:genetics*; D013030:Spain / Q000453:epidemiology; D044465:White People / Q000235:genetics* / Q000523:psychology
C046778:CMP-N-acetylneuraminate-poly-alpha-2,8-sialosyl sialyltransferase; D012799:Sialyltransferases
ST8SIAII; Schizophrenia; Sex