Sickle cell disease: taking a multidisciplinary approach.
A costly major public health concern, sickle cell disease (SCD) affects up to 100,000 Americans and can cause life-threatening complications. This article reviews the pathophysiology, signs and symptoms, diagnostic testing, management, and treatment of patients with SCD.
Beth Israel Medical Center, New York City, USA.
Stephanie
S
Apanah
Denise
D
Rizzolo
D000700:Analgesics / Q000627:therapeutic use; D000755:Anemia, Sickle Cell / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D000986:Antisickling Agents / Q000627:therapeutic use; D017707:Erythrocyte Transfusion; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D010146:Pain / Q000188:drug therapy / Q000209:etiology; D011008:Pneumococcal Infections / Q000209:etiology / Q000517:prevention & control
D000700:Analgesics; D000986:Antisickling Agents; D006918:Hydroxyurea