Total spondylectomy following carbon ion radiotherapy to treat chordoma of the mobile spine.
The main form of treatment of a chordoma of the mobile spine is total en bloc spondylectomy (TES), but the clinical results are not satisfactory. Stand-alone carbon ion radiotherapy (CIRT) for bone and soft-tissue sarcomas has recently been reported to have a high rate of local control with a low rate of local recurrence. We report two patients who underwent TES after CIRT for treating a chordoma in the lumbar spine with good medium-term outcomes. At operation, there remained histological evidence of viable tumour cells in both cases. After the combination use of TES following CIRT, neither patient showed signs of recurrence at the follow-up examination. These two cases suggest that CIRT should be combined with total spondylectomy in the treatment of chordoma of the mobile spine.
Nagoya University Graduate School of Medicine, Department of Orthopaedic Surgery, 65 Tsurumai-cho, Showa-ku, Nagoya city, Aichi 466-8550, Japan.
T
T
Matsumoto
S
S
Imagama
Z
Z
Ito
R
R
Imai
T
T
Kamada
Y
Y
Shimoyama
Y
Y
Matsuyama
N
N
Ishiguro
D000368:Aged; D002817:Chordoma / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D063193:Heavy Ion Radiotherapy / Q000379:methods*; D006801:Humans; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018365:Neoplasm, Residual / Q000473:pathology; D019637:Orthopedic Procedures / Q000379:methods; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D013904:Thoracic Vertebrae
Carbon ion radiotherapy; Chordoma; Histological findings; Mobile spine; Total spondylectomy