Acral coldness in migraineurs.
In search for new biomarkers of vascular disturbances accompanying migraine, we compared the facial and hand skin temperatures in 41 women, including 12 migraine patients during the headache-free period and 29 healthy controls. Compared to the controls, the acral skin temperatures were lower in migraineurs, especially in those with right-sided headache. Our findings suggest that migraine is associated with a peripheral coldness possibly due to abnormal autonomic vascular control. The cold nose and hands may represent easily assessable biomarkers of these disorders.
Institute of Biomedicine, University of Eastern Finland, P.O. Box 1627, FIN-70211 Kuopio, Finland; Institute of Dentistry, University of Eastern Finland, P.O. Box 1627, FIN-70211 Kuopio, Finland. Electronic address: nina.zaproudina@uef.fi.
Nina
N
Zaproudina
Department of Applied Physics, University of Eastern Finland, Kuopio, Finland.
Jukka A
JA
Lipponen
Department of Applied Physics, University of Eastern Finland, Kuopio, Finland.
Pasi A
PA
Karjalainen
Department of Applied Physics, University of Eastern Finland, Kuopio, Finland.
Alexei A
AA
Kamshilin
A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Rashid
R
Giniatullin
Institute of Biomedicine, University of Eastern Finland, P.O. Box 1627, FIN-70211 Kuopio, Finland; Institute of Dentistry, University of Eastern Finland, P.O. Box 1627, FIN-70211 Kuopio, Finland.
Matti
M
Närhi
D001794:Blood Pressure / Q000502:physiology; D003971:Diastole / Q000502:physiology; D005145:Face / Q000098:blood supply / Q000294:innervation / Q000503:physiopathology; D005260:Female; D005385:Fingers / Q000098:blood supply / Q000294:innervation / Q000503:physiopathology*; D006801:Humans; D008881:Migraine Disorders / Q000503:physiopathology*; D012881:Skin Temperature / Q000502:physiology*; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D014661:Vasoconstriction / Q000502:physiology; D014666:Vasomotor System / Q000503:physiopathology
Coldness; Migraine; Skin blood flow; Skin temperature; Vasoconstriction