A Possible Role of BA8 in Pre-surgical fMRI. Homage to an Exceptional Neuroscientist.
More than 100 years ago Korbinian Brodmann published an article on the cytoarchitecture of the cortical areas of the human brain. This article is meant to honor this great neuroscientist and his incredible thorough analysis of the cortical layers, a work that still remains a valid reference to present day neuroscientists. This is illustrated by the fMRI observation of co-activation of Brodmann's area 8 with activation of Broca, confirming Broca's activation even when the Broca area is displaced by tumor. This connection helps to ascertain and even quantify uni - or bilateral presence of the executive language area's. Although DTI-fiber tracking allows visualization of the connection between Broca's and Wernicke's area by the arcuate fasciculus, no such "wiring" could be shown between Broca's area and Brodmann's area 8.
VU Academic Medical Center, MRI Center; Amsterdam, The Netherlands - jaap.valk@mricentrum.nl.
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