Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria.
Triphenylphosphonium-fluorochromes (TPP-fluorochromes) are a new class of spectrally variable, mitochondrially targeted probes, with an [(18)F] labeling option which, when enabled, allows imaging of a cardiac perfusion deficit using PET/CT.
Center for Advanced Medical Imaging Sciences, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, USA. ljosephson@mgh.harvard.edu.
Hushan
H
Yuan
Hoonsung
H
Cho
Howard H
HH
Chen
Marcelo
M
Panagia
David E
DE
Sosnovik
Lee
L
Josephson