[Involvement of sympathetic nervous system in the pathogenesis of hypertension].
Sustained activation of sympathetic nervous system in response to stimulation of a wide variety of stress factors is an independent risk factor for the development of essential hypertension. Adrenal hormone biosynthesis pathway as an important part of the sympathetic nervous system consists of hormones, neurotransmitters, receptors, and a variety of synthases and invertases. In this article, we have systematically reviewed research progresses made in elucidating the interactions between genes of the adrenal hormone biosynthesis pathway and stress factors in the pathogenesis of essential hypertension.
Department of Hypertension, Xinjiang Medical University Affiliated Fifth Hospital, Urumqi, Xinjiang 830011, P. R. China. Email: guml@big.ac.cn.
Wenxi
W
Jiang
Xue-zhi
XZ
Zhang
Ming-liang
ML
Gu
D000818:Animals; D006728:Hormones / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D013564:Sympathetic Nervous System / Q000378:metabolism / Q000473:pathology*
D006728:Hormones