Genomics informs glioblastoma biology.
Identifying genomic alterations in cancer does not guarantee therapeutic benefit. A new study combining DNA and RNA sequencing with functional validation uncovers new genetic driver alterations in glioblastoma with potential for clinical translation.
Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
David L
DL
Schonberg
Shideng
S
Bao
Jeremy N
JN
Rich
D001932:Brain Neoplasms / Q000235:genetics*; D023281:Genomics; D005909:Glioblastoma / Q000235:genetics*; D006801:Humans