The clinical utilization of circulating cell free DNA (CCFDNA) in blood of cancer patients.
Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for the management of malignant and benign neoplasms. Detecting circulating DNA in cancer patients may help develop a DNA profile for early stage diagnosis in malignancies. The technical issues of obtaining, using, and analyzing CCFDNA from blood will be discussed.
Division of Cancer Research and Training, Department of Internal Medicine, Charles Drew University of Medicine and Science, 1720 East 120th Street, Los Angeles, CA 90059, USA. elshimali@gmail.com.
Yahya I
YI
Elshimali
Husseina
H
Khaddour
Marianna
M
Sarkissyan
Yanyuan
Y
Wu
Jaydutt V
JV
Vadgama
D004247:DNA / Q000097:blood*; D019175:DNA Methylation; D006801:Humans; D019656:Loss of Heterozygosity; D053842:Microsatellite Instability; D060885:Multiplex Polymerase Chain Reaction; D009369:Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000235:genetics
D004247:DNA