Regulation of hepatic glucose production by Gq-coupled receptors: potential new targets for treatment of type 2 diabetes.
Department of Pharmacology and Toxicology, University of Toronto, 1 King's College Circle, Room 4342, Toronto, Ontario, Canada, M5S 1A8. jane.mitchell@utoronto.ca.
Jane
J
Mitchell
D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000139:chemically induced*; D020536:Enzyme Activators / Q000009:adverse effects*; D005260:Female; D054768:G-Protein-Coupled Receptor Kinases / Q000378:metabolism*; D043802:GTP-Binding Protein alpha Subunits, Gq-G11 / Q000378:metabolism*; D005943:Gluconeogenesis / Q000187:drug effects*; D050261:Glycogenolysis / Q000187:drug effects*; D022781:Hepatocytes / Q000187:drug effects*; D006801:Humans; D008297:Male
D020536:Enzyme Activators; D054768:G-Protein-Coupled Receptor Kinases; D043802:GTP-Binding Protein alpha Subunits, Gq-G11