[Treatment of primary thyroid lymphomas].
Primary lymphomas of the thyroid (LPT) are a rare entity. LPT represent between 5 and 15% of all thyroid neoplasms. Cytology has limited value; biopsy should be recommended. The differential diagnosis of thyroid carcinoma is differentiated forms indolent or aggressive forms for anaplastic and high grade that may occur by a mass rapidly progressive and compressive. LPT represent a histologically and clinically heterogeneous disease. The most common forms are high-grade LPT (DBLCL) of diffuse large cell type or mucosa-associated lymphoid tissue (MALT). DBLCL receive chemotherapy. The benefit of irradiation is highly debated in view of the data from randomized lymphoma studies (nodal with a minority of extranodal forms) versus those of retrospective studies specifically addressing the case of LPT. Localized MALT lymphomas can be treated with radiation alone. The treatment of other LPT is presented.
CHRU de Besançon, département de radiothérapie, 3, boulevard Fleming, 25030 Besançon, France, Centre hospitalier Belfort-Montbéliard, département de radiothérapie, boulevard du Maréchal-Juin, 25209 Montbéliard cedex, France.
Xu Shan
XS
Sun
Jacques-Olivier
JO
Bay
Pierre-Yves
PY
Marcy
Yasser
Y
Hammoud
Alexis
A
Lacout
Jean-Jacques
JJ
Michels
Nicolas
N
Guevara
Juliette
J
Thariat
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D017728:Lymphoma, Large-Cell, Anaplastic / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D011379:Prognosis; D011879:Radiotherapy Dosage; D035583:Rare Diseases / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*
chemotherapy; lymphoma; radiotherapy; rare cancer; thyroid