Mycophenolic acid for lymphomatoid papulosis.
BACKGROUND
Lymphomatoid papulosis is a rare CD30+ lymphoproliferative T-cell disorder with limited effective treatments.


OBJECTIVE
We describe the case of a 50-year-old woman diagnosed with lymphomatoid papulosis who was unable to access phototherapy and who failed to clear while on systemic treatment with methotrexate.


METHODS
The patient was initiated on mycophenolate mofetil (MMF), a prodrug of mycophenolic acid, at a dose of 2 g divided twice daily.


RESULTS
MMF produced a rapid response with complete clearing within 8 weeks, and the patient has been successfully maintained for 2 years at the same dose with no noted side effects. Other patients in our clinic have had similar success.


CONCLUSIONS
Mycophenolic acid is a safe and well-tolerated therapy for lymphomatoid papulosis.
Trevor
T
Champagne
Scott
S
Walsh
D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D017731:Lymphomatoid Papulosis / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D009173:Mycophenolic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use; D012878:Skin Neoplasms / Q000188:drug therapy*
D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid