An INHIBIT logic gate from a thiophene derivative using iron and zinc ions as the input: tuning the efficiency on moving from naphthalene to anthracene to pyrene for the green luminescent detection of the intracellular iron.
A pyrene-thiophene conjugate has been used for the efficient detection of intracellular irons through the generation of bright green luminescence. Amongst three different probes being reported, it is observed that the efficiency for the naked eye green luminescent detection of iron increases on moving from naphthalene to anthracene to pyrene. The developed technique may be very useful to monitor iron and zinc supplementation as single micronutrients in living systems through the construction of an INHIBIT logic gate.
Department of Chemistry, The University of Burdwan, Burdwan, West Bengal, India. ddas100in@yahoo.com.
Arnab
A
Banerjee
Animesh
A
Sahana
Sudipta
S
Das
Sisir
S
Lohar
Bidisha
B
Sarkar
Subhra Kanti
SK
Mukhopadhyay
Jesús
J
Sanmartín Matalobos
Debasis
D
Das
D000873:Anthracenes / Q000737:chemistry*; D002176:Candida albicans / Q000737:chemistry / Q000378:metabolism; D018360:Crystallography, X-Ray; D007477:Ions / Q000737:chemistry; D007501:Iron / Q000032:analysis*; D008856:Microscopy, Fluorescence; D008968:Molecular Conformation; D009281:Naphthalenes / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013876:Thiophenes / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
D000873:Anthracenes; D007477:Ions; D009281:Naphthalenes; D011721:Pyrenes; D013876:Thiophenes; C031721:naphthalene; C030984:pyrene; D007501:Iron; C034020:anthracene; D015032:Zinc