Dendrimer-folate-copper conjugates as bioprobes for synchrotron X-ray fluorescence imaging.
We present a bioprobe for synchrotron X-ray fluorescence imaging based on dendrimer-folate-copper conjugates. The metal nanoclusters within a dendrimer exhibit excellent FR-targeting properties in KB cells. It could be used as a new multifunction bioprobe for synchrotron X-ray fluorescence mapping.
Division of Physical Biology, Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China. huangqing@sinap.ac.cn sunyanhong@sinap.ac.cn.
Yuanqing
Y
Zhang
Xiaoping
X
Xu
Lu
L
Wang
Jun
J
Lin
Ying
Y
Zhu
Zhi
Z
Guo
Yanhong
Y
Sun
Hua
H
Wang
Yun
Y
Zhao
Renzhong
R
Tai
Xiaohan
X
Yu
Chunhai
C
Fan
Qing
Q
Huang
D003300:Copper / Q000737:chemistry*; D050091:Dendrimers / Q000737:chemistry*; D005492:Folic Acid / Q000737:chemistry*; D006801:Humans; D007624:KB Cells; D015335:Molecular Probes / Q000737:chemistry* / Q000378:metabolism; D061848:Optical Imaging / Q000295:instrumentation / Q000379:methods*; D017356:Synchrotrons; D014965:X-Rays
D050091:Dendrimers; D015335:Molecular Probes; D003300:Copper; D005492:Folic Acid