Sonographic synovial vascularity of synovitis in rheumatoid arthritis.
RA is a condition of multiple synovitis. Abnormal synovial vascularity (SV) is evident with the onset of joint inflammation. The idea of estimating the level of joint inflammation by sonographic SV was conceived with the advancement of US. The ideal treatment strategy, called treat to target (T2T), requires early diagnosis and assessment of RA. Detection of positive SV can be useful for proving the presence of synovitis and finally diagnosing RA. In the assessment of RA, US-based global scores aimed at assessing overall disease activity have the potential to be useful for the achievement of T2T because US can directly detect changes in synovitis. Remaining SV in local joints increases the risk of structural deterioration. RA requires both improvement of overall disease activity and the disappearance of local SV for remission. The evaluation of SV provides various information and contributes to the clinical treatment of RA.
Hokkaido Medical Center for Rheumatic Diseases, 1-45, 3-Chome, 1-Jo, Kotoni, Nishi-ku, Sapporo 063-0811, Japan. jun.fukae@ryumachi-jp.com.
Jun
J
Fukae
Kazuhide
K
Tanimura
Tatsuya
T
Atsumi
Takao
T
Koike
D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging*; D012720:Severity of Illness Index; D013583:Synovial Membrane / Q000098:blood supply / Q000000981:diagnostic imaging*; D013585:Synovitis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000209:etiology; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler
D018501:Antirheumatic Agents
power Doppler sonography; rheumatoid arthritis; synovial vascularity; synovitis; treat to target; ultrasound