The concentration of manganese, iron, and strontium in hip joint bone obtained from patients undergoing hip replacement surgery.
The aim of this study was to determine the concentrations of manganese (Mn), iron (Fe) and strontium (Sr) in the cartilage with adjacent compact bone and spongy bone collected from patients after total hip replacement surgery. In addition, we examined relations between the concentrations of the metals in the bone and selected environmental factors. The concentration of Fe was the highest while Mn concentration was the lowest. The concentrations of Fe in the spongy bone in patients from larger cities were higher than in those living in smaller towns and villages. Significant correlations were found between Fe and Mn concentrations in the cartilage with adjacent compact bone and in the spongy bone, and between Mn and Sr in the spongy bone. In general, Mn, Fe and Sr concentrations in the bones of patients from NW Poland were lower than in other Polish regions and Europe, especially in industrialized countries. In conclusion, it seems that in addition to routine monitoring of the abiotic environment, it is essential to monitor concentrations of heavy metals having a long-term impact in humans.
Department of Biology and Medical Parasitology, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland; Department of Health Education, University of Szczecin, Piastow 40B, 71-065 Szczecin, Poland.
Halina
H
Budis
Department of Biology and Medical Parasitology, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Elzbieta
E
Kalisinska
Department of Biology and Medical Parasitology, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Natalia
N
Lanocha
Department of Biology and Medical Parasitology, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland. Electronic address: kodan@pum.edu.pl.
Danuta
D
Kosik-Bogacka
Chair and Clinics of Orthopedics and Traumatology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Sebastian
S
Sokolowski
Chair and Clinics of Orthopedics and Traumatology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Konrad
K
Dobiecki
Chair and Clinics of Orthopedics and Traumatology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Lukasz
L
Kolodziej
Chair and Clinics of Orthopedics and Traumatology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Andrzej
A
Bohatyrewicz
D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D005260:Female; D005270:Femur Head / Q000378:metabolism; D006621:Hip Joint / Q000378:metabolism*; D006801:Humans; D007501:Iron / Q000378:metabolism*; D008297:Male; D008345:Manganese / Q000378:metabolism*; D008875:Middle Aged; D013324:Strontium / Q000378:metabolism*
D008345:Manganese; D007501:Iron; D013324:Strontium
Femur head; Iron; Manganese; Strontium