A new indole alkaloidal glucoside from the aerial parts of Clematis terniflora DC.
A new indole alkaloidal glucoside together with three known compounds aurantiamide acetate (2), eleutheroside E (3) and 1-O-caffeoyl-β-D-glucopyranoside (4) has been isolated from ethanol extract of the aerial parts of Clematis terniflora DC. On the basis of their spectroscopic and chemical evidence, the new compound was elucidated as (6-O-β-D-glucopyranosyl-1H-indol-3-yl) carboxylic acid methyl ester (1). Compounds 1 and 3 showed significant cytotoxicity against human ECA-109.
a The Key Laboratory of Biomedical Engineering Ministry of Education, 38 Zheda Road, Zhejiang University , Hangzhou, 310027 Zhejiang , P.R. China.
Wen-Ting
WT
Li
Bing-Xian
BX
Yang
Wei
W
Zhu
Ming-Hua
MH
Gong
Xiang-Dong
XD
Xu
Xiang-Hong
XH
Lu
Lian-Li
LL
Sun
Jing-Kui
JK
Tian
Lin
L
Zhang
D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D039324:Clematis / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D026121:Indole Alkaloids / Q000737:chemistry* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry*
D005960:Glucosides; D026121:Indole Alkaloids