Generalized acanthosis nigricans without systemic disease associated.
Acanthosis nigricans (OMIM ID % 100600) is a dermatosis characterized by velvety hyperpigmentation, skin thickening, and papillomatosis. It mainly affects flexural areas. In most cases, the generalized form is related to malignancy in adults; it is rarely reported in the absence of systemic disease in children and adolescents. The present report is aimed at describing an unusual case of generalized acanthosis nigricans in a 17 year-old patient, in which, after extensive investigation (clinical, laboratorial and by imaging methods) no association with systemic disease was found.
School of Medical Sciences, Universidade de Marilia.
Rafael
R
Denadai
Ricardo Martinhao
RM
Souto
Mariam Patricia
MP
Auada-Souto
D000052:Acanthosis Nigricans / Q000145:classification / Q000175:diagnosis* / Q000473:pathology; D000293:Adolescent; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D018450:Disease Progression; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019344:Lactic Acid / Q000008:administration & dosage / Q000627:therapeutic use; D012880:Skin Pigmentation; D014212:Tretinoin / Q000008:administration & dosage / Q000627:therapeutic use
D003879:Dermatologic Agents; D019344:Lactic Acid; D014212:Tretinoin