Direct construction of quaternary carbons from tertiary alcohols via photoredox-catalyzed fragmentation of tert-alkyl N-phthalimidoyl oxalates.
A convenient method for the direct construction of quaternary carbons from tertiary alcohols by visible-light photoredox coupling of tert-alkyl N-phthalimidoyl oxalate intermediates with electron-deficient alkenes is reported.
Department of Chemistry, University of California , Irvine, California 92697-2025, United States.
Gregory L
GL
Lackner
Kyle W
KW
Quasdorf
Larry E
LE
Overman
D000438:Alcohols / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D004583:Electrons; D008027:Light; D010070:Oxalates / Q000737:chemistry*; D010084:Oxidation-Reduction; D055668:Photochemical Processes; D010797:Phthalimides / Q000737:chemistry*; D013237:Stereoisomerism
D000438:Alcohols; D000475:Alkenes; D010070:Oxalates; D010797:Phthalimides; D002244:Carbon