Novel intergenotype human norovirus recombinant GII.16/GII.3 in Bangladesh.
Noroviruses (NoVs) are one of the major etiological agents of acute gastroenteritis in all age groups. In this study, we identified an intergenotype NoV recombinant strain in the fecal specimens of two male infants with acute diarrhea in Bangladesh. Phylogenetic analysis showed that the identified strains were recombinant NoV strains with a GII.3 capsid and a GII.16 polymerase gene. The recombination breakpoint was located in the ORF1/ORF2 overlap region. To the best of our knowledge this is the first report of a NoV recombinant GII.16/GII.3 strain worldwide.
Department of Microbiology, Jahangirnagar University, Savar, Dhaka, Bangladesh. Electronic address: nahar_28@yahoo.com.
Shamsun
S
Nahar
Mokibul Hassan
MH
Afrad
Jelle
J
Matthijnssens
Mohammed Ziaur
MZ
Rahman
Zehadee
Z
Momtaz
Rahena
R
Yasmin
Mohammad
M
Jubair
Abu Syed Golam
AS
Faruque
Mohammad Sahabuddin Kabir
MS
Choudhuri
Tasnim
T
Azim
Mustafizur
M
Rahman
D001459:Bangladesh; D001483:Base Sequence; D017250:Caliciviridae Infections / Q000235:genetics* / Q000821:virology; D036022:Capsid Proteins / Q000235:genetics*; D003967:Diarrhea / Q000821:virology; D005243:Feces / Q000821:virology; D005759:Gastroenteritis / Q000235:genetics* / Q000821:virology; D014644:Genetic Variation; D006801:Humans; D007223:Infant; D008297:Male; D008969:Molecular Sequence Data; D029322:Norovirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D016366:Open Reading Frames / Q000235:genetics; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D012324:RNA-Dependent RNA Polymerase / Q000235:genetics*; D011995:Recombination, Genetic; D017423:Sequence Analysis, RNA
D036022:Capsid Proteins; D012367:RNA, Viral; D012324:RNA-Dependent RNA Polymerase
Bangladesh; Diarrhea; GII.16; GII.3; Norovirus; Recombinant