Efficient chromium(II)-catalyzed cross-coupling reactions between Csp2 centers.
Low-toxicity chromium(II) chloride catalyzes at 25 °C within minutes the coupling reactions of various (hetero)arylmagnesium reagents with N-heterocyclic halides, aromatic halogenated ketones or imines, and alkenyl iodides. Remarkably, much lower amounts of homo-coupling side products are obtained compared to related iron, cobalt, or manganese cross-couplings.
Department of Chemistry, Ludwig-Maximilians-Universität , Butenandtstrasse 5-13, 81377 Munich, Germany.
Andreas K
AK
Steib
Olesya M
OM
Kuzmina
Sarah
S
Fernandez
Dietmar
D
Flubacher
Paul
P
Knochel
D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D017608:Chromium Compounds / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry
D002712:Chlorides; D017608:Chromium Compounds; D009942:Organometallic Compounds; C017133:chromous chloride