Palladium-catalyzed decarboxylative ortho acylation of azobenzenes with α-oxocarboxylic acids.
A palladium-catalyzed decarboxylative ortho acylation of azobenzenes with α-oxocarboxylic acids via ligand-directed C-H activation has been explored. The reaction proceeded smoothly with potassium persulfate as the oxidant to afford acylated unsymmetrical azobenzenes in moderate to good yields and tolerated chloro, bromo, iodo, and methoxy groups. Para, ortho, and disubstituted as well as unsymmetrical azobenzenes could be used.
CAS Key Laboratory of Soft Matter Chemistry, Hefei National Laboratory for Physical Sciences at Microscale, and Department of Chemistry, University of Science and Technology of China , Hefei, Anhui 230026, People's Republic of China.
Zhong-Yuan
ZY
Li
Dan-Dan
DD
Li
Guan-Wu
GW
Wang