[Papilledema secondary to tuberculous meningitis in a patient with type 1 diabetes mellitus].
METHODS
The case is presented of a 29-year-old woman who complained of headache over a period of several days, with loss of visual acuity and pain in her left eye. She had a 3-year history of type 1 diabetes mellitus, and was an immigrant from Ecuador. The funduscopic examination revealed a papilledema. The polymerase chain reaction (PCR) study of the cerebrospinal fluid was positive for Mycobacterium tuberculosis (MTB). She showed a marked improvement after treatment with anti-TB drugs.


CONCLUSIONS
About a third of the world's population has a latent infection of MTB, comorbidity between diabetes mellitus and tuberculosis has been reported, particularly in undeveloped countries.
Servicio de Oftalmología, Hospital Universitario Dr. Peset, Valencia, España. Electronic address: jpcaire@hotmail.com.
J P
JP
Caire Estévez
S
S
González-Ocampo Dorta
P
P
Sanz Solana
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D001284:Atrophy; D002555:Cerebrospinal Fluid / Q000382:microbiology; D003906:Developing Countries; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D004359:Drug Therapy, Combination; D004484:Ecuador / Q000208:ethnology; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007538:Isoniazid / Q000627:therapeutic use; D055985:Latent Tuberculosis / Q000453:epidemiology; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D009887:Ophthalmoscopy; D009900:Optic Nerve / Q000473:pathology; D010211:Papilledema / Q000209:etiology*; D012293:Rifampin / Q000627:therapeutic use; D013129:Spinal Puncture; D014374:Tuberculin Test; D014390:Tuberculosis, Meningeal / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis*
D000995:Antitubercular Agents; D007538:Isoniazid; D012293:Rifampin
Diabetes mellitus; Papiledema; Papilledema; Países en vías de desarrollo; Polymerase chain reaction; Reacción en cadena de la polimerasa; Tuberculosis meníngea; Tuberculous meningitis; Undeveloped countries