Short Interval Infield Sarcoma Development following Resection of Glioblastoma and Adjuvant Radiotherapy and Temozolomide.
Background. The development of 2 unassociated brain cancers in the same patient is a rare occurrence. Secondary cancers are generally thought to develop as an oncogenic consequence of the radiation therapy delivered to treat the primary cancers, always requiring a significant time interval between radiation treatment and secondary cancer development. Case Description. We report the development of an undifferentiated myxoid sarcoma only 13 months following radiation therapy for a glioblastoma. Conclusion. This case represents the shortest time interval reported between radiation therapy and secondary brain cancer development.
Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University and Department of Neurosurgery, McGill University Health Centre, 3801 University Avenue, 109 Montreal, QC, Canada H3A 2B4.
Fahad E
FE
Alotaibi
Kevin
K
Petrecca