Pooling ocular swab specimens from Tanzania for testing by Roche Amplicor and Aptima Combo 2 assays for the detection of Chlamydia trachomatis: accuracy and cost-savings.
Ocular swabs collected in Tanzania were evaluated by Amplicor CT PCR and Aptima Combo2 assays for the detection of Chlamydia trachomatis to determine if pooling could be used to reduce the cost of detection. Pooling would be an accurate method and has thus far resulted in a cost-savings of 62.2%.
Division of Infectious Diseases and Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA. Electronic address: Ldize2@jhmi.edu.
Laura
L
Dize
Sheila
S
West
Thomas C
TC
Quinn
Charlotte A
CA
Gaydos
D002690:Chlamydia Infections / Q000175:diagnosis*; D002692:Chlamydia trachomatis / Q000235:genetics*; D017046:Cost Savings; D015818:Eye Infections, Bacterial / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction / Q000379:methods; D011933:Reagent Kits, Diagnostic / Q000191:economics / Q000592:standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013636:Tanzania
D011933:Reagent Kits, Diagnostic
Chlamydia trachomatis; Cost-savings; Pooling; Trachoma