First trimester maternal serum vitamin D and markers of preeclampsia.
OBJECTIVE
There is evidence that vitamin D deficiency is associated with preeclampsia. The aim of the study was to determine if maternal levels of vitamin D at 1st trimester were related to markers of preeclampsia.


METHODS
Serum levels of 25-hydroxy-vitamin D (25OHD), PAPP-A, PlGF, uterine artery pulsatility index and mean arterial pressure were measured in 280 pregnant women.


RESULTS
Preeclampsia markers were not related to 25OHD concentration.


CONCLUSIONS
First trimester maternal serum concentration of vitamin D does not seem to be connected with markers of preeclampsia.
1st Department of Obstetrics and Gynecology and.
Dorota A
DA
Bomba-Opon
Robert
R
Brawura-Biskupski-Samaha
Szymon
S
Kozlowski
Przemyslaw
P
Kosinski
Zbigniew
Z
Bartoszewicz
Tomasz
T
Bednarczuk
Miroslaw
M
Wielgos
D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D000072483:Placenta Growth Factor; D011225:Pre-Eclampsia / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000097:blood; D011261:Pregnancy Trimester, First / Q000097:blood*; D011266:Pregnancy-Associated Plasma Protein-A / Q000378:metabolism; D012307:Risk Factors; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications* / Q000175:diagnosis
D015415:Biomarkers; C000608036:PGF protein, human; D011257:Pregnancy Proteins; D014807:Vitamin D; D000072483:Placenta Growth Factor; C104450:25-hydroxyvitamin D; D011266:Pregnancy-Associated Plasma Protein-A
Mean artery pressure; PAPP-A; PlGF; preeclampsia; pregnancy; uterine artery pulsatility index; vitamin D