Zebrafish-based small molecule screens for novel cardiovascular drugs.
The zebrafish is increasingly being adopted as an in vivo model of high throughput drug screening. In this brief review we outline the advantages and disadvantages of this approach and summarize recent screens that have attempted to identify novel small molecules with activity on the cardiovascular system.
Peter
P
Novodvorsky
Marc M J
MM
Da Costa
Timothy J A
TJ
Chico
D000818:Animals; D002317:Cardiovascular Agents; D004353:Drug Evaluation, Preclinical; D057166:High-Throughput Screening Assays; D015027:Zebrafish
D002317:Cardiovascular Agents