Severe pertussis in newborns and young vulnerable infants.
A retrospective chart review of 18 nonvaccinated newborns and infants admitted to 6 intensive care units in the north of Portugal between 2007 and 2012 revealed a high rate of admissions in 2012 along with significant rates of severe pulmonary hypertension and mortality. Hyperleukocytosis was significantly associated with a more severe clinical picture and mortality.
From the *Division of Neonatology, Department of Pediatrics, Hospital de São João; †Faculty of Medicine, Porto University; ‡Division of Neonatology, Maternidade Júlio Dinis; §Neonatal and Pediatric Intensive Care Unit, Hospital Geral de Santo António; ¶Division of Neonatology, Department of Pediatrics, Centro Hospitalar de Vila Nova de Gaia; ‖Neonatal Intensive Care Unit, Department of Pediatrics, Hospital Pedro Hispano, Matosinhos, Porto; and **Neonatal Intensive Care Unit, Department of Pediatrics, Hospital de Braga, Braga, Portugal.
Gustavo
G
Rocha
Filipa
F
Flôr-de-Lima
Paulo
P
Soares
Henrique
H
Soares
Susana
S
Pissarra
Elisa
E
Proença
Paula
P
Fernandes
Conceição
C
Quintas
Teresa
T
Martins
Albina
A
Silva
Hercília
H
Guimarães
D003371:Cough; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data; D007958:Leukocyte Count; D011174:Portugal / Q000453:epidemiology; D012189:Retrospective Studies; D014917:Whooping Cough / Q000097:blood / Q000453:epidemiology*