Electrophysiological tests in evaluation of glaucoma and ocular hypertension treatment--up to date knowledge. A review.
OBJECTIVE
On the basis of the literature data to assess the efficacy of the electrophysiological tests (pattern electroretinogram, multifocal electroretinogram and multifocal visual evoked potentials) in evaluation of retinal ganglion cells function in glaucomatous and ocular hypertension eyes, after intraocular pressure reduction.


METHODS
Data published in the literature available at the Pub Med library between 1964-2012.


RESULTS
Several results of studies suggest, that steady-state pattern electroretinogram reveals significant improvement of retinal ganglion cells function after treatment with timolol, acatazolamide, beta-blockers and prostaglandin analogues. Multifocal electroretinograms' changes, after lowering the intraocular pressure by trabeculectomy, were confirmed in only one study, There were no statistically significant correlations between changes in intraocular pressure reduction and multifocal visual evoked potentials.


CONCLUSIONS
Steady state pattern electroretinogram is the most commonly used electrophysiological test in evaluating the results of glaucoma and ocular hypertension treatment.
Department of Ophthalmology, Pomeranian Medical University, Szczecin, Poland. karaskiewicz.joanna@gmail.com
Joanna
J
Karaśkiewicz
Wojciech
W
Lubiński
Krzysztof
K
Penkala
D000086:Acetazolamide / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D004596:Electroretinography / Q000379:methods*; D005901:Glaucoma / Q000175:diagnosis* / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D007429:Intraocular Pressure; D009798:Ocular Hypertension / Q000175:diagnosis* / Q000188:drug therapy / Q000628:therapy*; D009883:Ophthalmic Solutions / Q000008:administration & dosage; D011461:Prostaglandins F, Synthetic / Q000008:administration & dosage; D013999:Timolol / Q000008:administration & dosage; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome
D009883:Ophthalmic Solutions; D011461:Prostaglandins F, Synthetic; D013999:Timolol; D000086:Acetazolamide