Mechanical nociception thresholds in lame sows: evidence of hyperalgesia as measured by two different methods.
Lameness is a frequently occurring, painful condition of breeding sows that may result in hyperalgesia, i.e., an increased sensitivity to pain. In this study a mechanical nociception threshold (MT) test was used (1) to determine if hyperalgesia occurs in sows with naturally-occurring lameness; (2) to compare measurements obtained with a hand-held probe and a limb-mounted actuator connected to a digital algometer; and (3) to investigate the systematic left-to-right and cranial-to-caudal differences in MT. Twenty-eight pregnant sows were investigated, of which 14 were moderately lame and 14 were not lame. Over three testing sessions, repeated measurements were taken at 5 min intervals on the dorsal aspects of the metatarsi and metacarpi of all limbs. The MT was defined as the force in Newtons (N) that elicited an avoidance response, and this parameter was found to be lower in limbs affected by lameness than in normal limbs (P<0.05). Forelimbs had higher MTs than hindlimbs (P<0.001). The hand-held probe systematically yielded lower values than the actuator (P<0.001), and the MT differed between morning and afternoon testing sessions (P<0.001), as well as between days (P<0.001). The findings provide evidence that lame sows experience hyperalgesia. Systematic differences between forelimb and hindlimb MT must be taken into account when such assessments are performed.
Institute for Agricultural and Fisheries Research (ILVO), Animal Sciences Unit, Scheldeweg 68, 9090 Melle, Belgium; Ghent University, Faculty of Veterinary Medicine, Department of Obstetrics, Reproduction and Herd Health, Salisburylaan 133, 9820 Merelbeke, Belgium. Electronic address: elena.nalon@gmail.com.
E
E
Nalon
D
D
Maes
S
S
Piepers
M M J
MM
van Riet
G P J
GP
Janssens
S
S
Millet
F A M
FA
Tuyttens
D000822:Animal Husbandry / Q000379:methods*; D000818:Animals; D001696:Biomechanical Phenomena; D005260:Female; D006930:Hyperalgesia / Q000209:etiology / Q000503:physiopathology / Q000662:veterinary*; D007794:Lameness, Animal / Q000209:etiology / Q000503:physiopathology*; D059225:Nociception; D013552:Swine; D013553:Swine Diseases / Q000209:etiology / Q000503:physiopathology*
Hyperalgesia; Lameness; Mechanical threshold; Nociception; Sow