Wide linear-range detecting nonenzymatic glucose biosensor based on CuO nanoparticles inkjet-printed on electrodes.
Inkjet-printed copper oxide nanoparticles (CuO NPs) on silver electrodes were used to fabricate the nonenzymatic glucose biosensor. The inkjet-printed CuO NPs electrodes produced high and reproducible sensitivity of 2762.5 μAm M(-1) cm(-2) at an applied potential of +0.60 V with the wide linear-detecting range of 0.05-18.45 mM and the detection limit of ~0.5 μM (S/N = 3). The long-term stability and reproducibility of sensor in glucose electro-oxidation resulted from the chemical stability of CuO NPs and pore-like structure formed on Ag surface, which prevented the CuO NPs from conglomeration and the interference of oxygen in the air. Significantly, the effect of interfering species, such as AA, UA, and DA were negligible, whereas sugar derivatives (lactose, fructose, and mannose) show insignificant interference. Finally, the electrode was applied to analyze glucose concentration in human serum samples.
Department of BIN Fusion Technology, School of Semiconductor and Chemical Engineering, Chonbuk National University , 567 Baekje-daero, Deokjin-gu, Jeonju 561-756, Republic of Korea.
Rafiq
R
Ahmad
Mohammad
M
Vaseem
Nirmalya
N
Tripathy
Yoon-Bong
YB
Hahn
D015374:Biosensing Techniques; D003300:Copper / Q000737:chemistry*; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D053768:Metal Nanoparticles; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D014961:X-Ray Diffraction
D003300:Copper; D005947:Glucose; C000520:cuprous oxide