No indication for an unexpected high rate of coronary artery aneurysms after angioplasty with drug-coated balloons.
OBJECTIVE
Coronary artery aneurysms (CAA) are a rare complication after percutaneous coronary intervention (PCI) and are reported with an incidence of 0.6% to 3.9%. While in recent years the use of paclitaxel drug-coated balloons (DCB) has increased, so far no CAA formation after DCB intervention has been reported.


RESULTS
During the years 2010 and 2011 we used DCBs in 704 PCIs. Follow-up angiography was scheduled at four months in all patients and has so far been achieved in 380 PCIs. In three patients we found development of a CAA at the former PCI site within four months of observation. Aneurysm length varied between 8.4 mm and 13 mm and lumina increased 58% to 131%. Retrospectively all patients with CAA development showed small intimal dissection partially with tiny persisting contrast bands parallel to the lumen according to type B and type C of the NHLBI classification after PCI.


CONCLUSIONS
CAA formation after DCB intervention was found in three out of 380 PCIs with DCB, consistent with an incidence of 0.8%. Thus, PCI with DCB does not cause an unexpectedly high rate of coronary artery aneurysms.
Charité - University Medicine Berlin, Berlin, Germany.
Franz X
FX
Kleber
Antonia
A
Schulz
Klaus
K
Bonaventura
Annette
A
Fengler
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D003323:Coronary Aneurysm / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D023903:Coronary Restenosis / Q000453:epidemiology*; D054855:Drug-Eluting Stents / Q000009:adverse effects; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects*; D012189:Retrospective Studies; D016896:Treatment Outcome