[Progress in stable isotope labeled quantitative proteomics methods].
Quantitative proteomics is an important research field in post-genomics era. There are two strategies for proteome quantification: label-free methods and stable isotope labeling methods which have become the most important strategy for quantitative proteomics at present. In the past few years, a number of quantitative methods have been developed, which support the fast development in biology research. In this work, we discuss the progress in the stable isotope labeling methods for quantitative proteomics including relative and absolute quantitative proteomics, and then give our opinions on the outlook of proteome quantification methods.
Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, National Chromatographic Research and Analysis Center, Dalian 116023, China.
Yuan
Y
Zhou
Yichu
Y
Shan
Lihua
L
Zhang
Yukui
Y
Zhang
D007553:Isotope Labeling; D040901:Proteomics / Q000379:methods*