A novel sodium iodide and ammonium molybdate co-catalytic system for the efficient synthesis of 2-benzimidazoles using hydrogen peroxide under ultrasound irradiation.
The reaction of aldehydes and o-phenylenediamine for the preparation of 2-benzimidazoles has been studied using hydrogen peroxide as an oxidant under ultrasound irradiation at room temperature in this paper. The combination of substoichiometric sodium iodide and ammonium molybdate as co-catalysts, together with using small amounts of hydrogen peroxide, makes this transformation very efficient and attractive under ultrasound. Thus, a mild, green and efficient method is established to carry out this reaction in high yield.
Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, PR China. Electronic address: baiguoyi@hotmail.com.
Guo-Yi
GY
Bai
Xing-Wang
XW
Lan
Guo-Feng
GF
Chen
Xiao-Fang
XF
Liu
Tian-Yu
TY
Li
Ling-Juan
LJ
Shi
D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D055772:Green Chemistry Technology; D006861:Hydrogen Peroxide / Q000737:chemistry*; D008982:Molybdenum / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry; D012974:Sodium Iodide / Q000737:chemistry*; D014465:Ultrasonics
D001562:Benzimidazoles; D016877:Oxidants; D008982:Molybdenum; D006861:Hydrogen Peroxide; D012974:Sodium Iodide; C022175:ammonium molybdate
Aldehydes; Benzimidazole; Hydrogen peroxide; Ultrasound; o-Phenylenediamine