Visual outcomes comparison of 2 femtosecond laser platforms for laser in situ keratomileusis.
OBJECTIVE
To compare the efficacy, predictability, and safety outcomes of 2 femtosecond laser platforms for flap creation during laser in situ keratomileusis (LASIK) for myopia and myopic astigmatism.


METHODS
Singapore National Eye Centre, Singapore.


METHODS
Retrospective case review.


METHODS
In this single-center multisurgeon study, patients had LASIK with flaps created using a Visumax 500 kHz or Intralase 60 kHz femtosecond laser system. Ablation was performed with the Wavelight Allegretto Eye-Q 400 Hz excimer laser in all patients. Preoperative and 3-month postoperative manifest refraction, attempted treatment spherical equivalent (SE), visual acuity, and complications were compared.


RESULTS
The 500 kHz femtosecond laser group comprised 381 patients (381 eyes) and the 60 kHz femtosecond laser group, 362 patients (362 eyes). Three months postoperatively, the uncorrected distance visual acuity was 20/40 or better in 99.1% of eyes in the 60 kHz laser group and 99.4% of eyes in the 500 kHz laser group (P=.678). Regarding predictability, 98.6% of eyes and 97.4% of eyes, respectively, were within ± 1.0 diopter of the attempted SE correction postoperatively (P=.228). The safety index was similar in the 60 kHz laser group and the 500 kHz laser group (mean 1.06 ± 0.16 [SD] versus 1.05 ± 0.14) (P=.321).


CONCLUSIONS
The safety, predictability, and efficacy profiles of the 500 kHz femtosecond platform for LASIK were excellent and comparable to those of the 60 kHz platform.
From Singapore National Eye Centre (Ang, Mehta, Rosman, Li, Koh, Tan, Chan), Singapore Eye Research Institute (Ang, Mehta, Htoon, Rosman, Li, Tan), Duke-NUS Graduate Medical School (Mehta), and the National University Health System (Mehta, Tan), Singapore.
Marcus
M
Ang
Jodhbir S
JS
Mehta
Mohamad
M
Rosman
Lim
L
Li
Jane C W
JC
Koh
Hla M
HM
Htoon
Donald
D
Tan
Cordelia
C
Chan
D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D012029:Refraction, Ocular; D012189:Retrospective Studies; D013524:Surgical Flaps; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology*; D055815:Young Adult