Organocatalyzed enantioselective desymmetrization of aziridines and epoxides.
Enantioselective desymmetrization of meso-aziridines and meso-epoxides with various nucleophiles by organocatalysis has emerged as a cutting-edge approach in recent years. This review summarizes the origin and recent developments of enantioselective desymmetrization of meso-aziridines and meso-epoxides in the presence of organocatalysts.
Department of Medicinal Chemistry, School of Pharmacy, Fourth Military Medical University, Changle Xilu 17, Xi-An, 710032, P. R. China.
Ping-An
PA
Wang
aziridine; desymmetrization; enantioselectivity; epoxide; organocatalysis