A practical approach to radiological evaluation of CT lung cancer screening examinations.
Lung cancer is the most common cause of cancer-related death in the world. The Dutch-Belgian Randomized Lung Cancer Screening Trial (Dutch acronym: NELSON) was launched to investigate whether screening for lung cancer by low-dose multidetector computed tomography (CT) in high-risk patients will lead to a decrease in lung cancer mortality. The NELSON lung nodule management is based on nodule volumetry and volume doubling time assessment. Evaluation of CT examinations in lung cancer screening can also include assessment of coronary calcification, emphysema and airway wall thickness, biomarkers for major diseases that share risk factors with lung cancer. In this review, a practical approach to the radiological evaluation of CT lung cancer screening examinations is described.
Center for Medical Imaging - North East Netherlands, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Radiology, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.
Xueqian
X
Xie
Marjolein A
MA
Heuvelmans
Peter M A
PM
van Ooijen
Matthijs
M
Oudkerk
Rozemarijn
R
Vliegenthart
D003324:Coronary Artery Disease / Q000000981:diagnostic imaging; D055088:Early Detection of Cancer; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D011656:Pulmonary Emphysema / Q000000981:diagnostic imaging; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000379:methods*; D061205:Vascular Calcification / Q000000981:diagnostic imaging