[Primary hyperaldosteronism with adrenal adenoma or hyperplasia: surgical case or not?].
Primary hyperaldosteronism is one of the most frequent causes of secondary hypertension. Cardiovascular morbimortality is higher than in essential hypertonic and justifies diagnostic and specific treatment of this pathology. Therapeutic choice depends of health and desire of the patient. It is either medical with mineralocorticoid receptor antagonists, or surgical through adrenalectomy. In this case, a pre-surgery exam including a radiologic examination and a venous adrenal catheterism has to be done. Surgery allows a normalisation of kaliema and a blood pressure decrease in 50 to 88% of the patients. Beyond them, 30% are able to stop entirely their medication. Both therapeutic choices decrease cardiovascular risks equally if blood pressure is controlled.
Service de néphrologie, CHUV, 1011 Lausanne. marie-eve.muller@chuv.ch
Marie-Eve
ME
Muller
Francesco
F
Doenz
Maurice
M
Matter
Grégoire
G
Wuerzner
Michel
M
Burnier
D000306:Adrenal Cortex Neoplasms / Q000473:pathology / Q000601:surgery*; D018246:Adrenocortical Adenoma / Q000473:pathology / Q000601:surgery*; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications / Q000209:etiology*; D006965:Hyperplasia; D006973:Hypertension / Q000209:etiology*; D008875:Middle Aged