Physicochemical properties of silica gel coated with a thin layer of polyaniline (PANI) and its application in non-suppressed ion chromatography.
Physicochemical properties of a new sorbent and its potential application in non-suppressed ion chromatography (IC) have been investigated. The sorbent was obtained in a process of covering silica gel particles with a film of polyaniline (PANI). The properties of silica modified with polyaniline such as particle size, porosity, average quantity of polyaniline covering carrier and density of sorbent were determined. In our study the following methods were used: microscopic analysis, laser diffraction technique, combustion analysis, mercury porosimetry and helium pycnometry. Column with the newly obtained packing was used for the separation of inorganic anions. Optimized chromatographic system was successfully employed for analysis of iodide and bromide in selected pharmaceutical products (Bochnia salt and Iwonicz salt) applied in chronic respiratory disease. Analysis was carried out using 0.1M solution of HCl in mixture of methanol/water (50:50v/v) as a mobile phase; the flow rate was 0.3 mL min(-1), temperature was 24°C and λ=210 nm. Validation parameters such as correlation coefficient, RSD values, recovery, detection and quantification limits were found to be satisfactory.
Department of Analytical Chemistry, Medical University, Chodźki 4a, 20-093 Lublin, Poland. Electronic address: i.sowa@umlub.pl.
Ireneusz
I
Sowa
Ryszard
R
Kocjan
Magdalena
M
Wójciak-Kosior
Ryszard
R
Swieboda
Dominika
D
Zajdel
Mieczysław
M
Hajnos
D000814:Aniline Compounds; D001965:Bromides / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods*; D007454:Iodides / Q000302:isolation & purification*; D010316:Particle Size; D016062:Porosity; D058428:Silica Gel / Q000737:chemistry*; D012996:Solutions; D014867:Water
D000814:Aniline Compounds; D001965:Bromides; D007454:Iodides; D012996:Solutions; C416807:polyaniline; D014867:Water; D058428:Silica Gel
Iodide; New stationary phase; Non-suppressed ion chromatography; Physicochemical properties of stationary phases; Polyaniline