title: Invasive Aspergillus niger complex infections in a Belgian tertiary care hospital.
abstract: The incidence of invasive infections caused by the Aspergillus niger species complex was 0.043 cases/10 000 patient-days in a Belgian university hospital (2005-2011). Molecular typing was performed on six available A. niger complex isolates involved in invasive disease from 2010 to 2011, revealing A. tubingensis, which has higher triazole minimal inhibitory concentrations, in five out of six cases.
authors.affiliation: Catholic University of Leuven, Leuven, Belgium.
authors.forename: E
authors.initials: E
authors.lastname: Vermeulen
authors.forename: J
authors.initials: J
authors.lastname: Maertens
authors.forename: P
authors.initials: P
authors.lastname: Meersseman
authors.forename: V
authors.initials: V
authors.lastname: Saegeman
authors.forename: L
authors.initials: L
authors.lastname: Dupont
authors.forename: K
authors.initials: K
authors.lastname: Lagrou
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use*; D001228:Aspergillosis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*; D001234:Aspergillus niger / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification*; D001530:Belgium; D005260:Female; D006801:Humans; D015994:Incidence; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D058889:Molecular Typing; D016533:Mycological Typing Techniques; D012189:Retrospective Studies; D062606:Tertiary Care Centers; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D014230:Triazoles; D017964:Itraconazole; C101425:posaconazole; D065819:Voriconazole
keywords: Aspergillosis; Aspergillus niger; Aspergillus niger infection; Invasive pulmonary aspergillosis; drug resistance; fungal