title: Using of porous portion to simulate pulmonary resistance in the computational fluid dynamic models of Fontan connection.
abstract: In this study, we performed computational fluid dynamic (CFD) simulations in a patient-specific three-dimensional extracardiac conduit Fontan connection. The pulmonary resistance was incorporated in the CFD model by connecting porous portions in the left and right pulmonary arteries. The pressure in the common atrium was set as boundary conditions at the outlets of the pulmonary arteries. The flow rate in the innominate veins and the inferior vena cava (IVC) was set as inflow boundary conditions. Furthermore, the inflow rate of IVC was increased to 2 and 3 times of that measured to perform another two simulations and the resistance provided by the porous portions was compared among these three conditions. We found out that the pulmonary resistance set as porous portion in the CFD models remains relatively steady despite the change of the inflow rate. We concluded that, in the CFD simulations for the Fontan connections, porous portion could be used to represent pulmonary resistance steadily. The pulmonary resistance and pressure in the common atrium could be acquired directly by clinical examination. The employment of porous portion together with pressure in the common atrium in the CFD model could facilitate and accurate the set of outlet boundary conditions especially for those actual pulmonary flow splits was unpredictable such as virtual operative designs related CFD simulations.
authors.forename: Qi
authors.initials: Q
authors.lastname: Sun
authors.forename: Jinlong
authors.initials: J
authors.lastname: Liu
authors.forename: Yi
authors.initials: Y
authors.lastname: Qian
authors.forename: Haifa
authors.initials: H
authors.lastname: Hong
authors.forename: Jinfen
authors.initials: J
authors.lastname: Liu
mesh_terms: D002675:Child, Preschool; D003198:Computer Simulation; D018729:Fontan Procedure; D006330:Heart Defects, Congenital / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D057446:Hydrodynamics; D021621:Imaging, Three-Dimensional; D008297:Male; D011651:Pulmonary Artery / Q000503:physiopathology / Q000601:surgery; D014655:Vascular Resistance