title: Wearable cuff-less PTT-based system for overnight blood pressure monitoring.
abstract: A wearable cuff-less pulse transit time (PTT) based monitoring device is developed for ambulatory blood pressure (BP) monitoring. Ten healthy subjects (aged 27 ± 4 years old) underwent 24-hour ambulatory BP monitoring using 1) a standard brachial cuff-based oscillometric device as reference and 2) the proposed cuff-less PTT measuring system. Raw PTT and BP measurements were linearly interpolated and then smoothed by a low-pass filter to remove aliasing effect caused by the low sampling rate and synchronized. Resampled PTT and BP were assessed for correlation using correlation coefficients and Bland-Altman plots. Our study showed that PTT estimated systolic BP most accurately within 4.8 ± 4.3 mmHg on healthy young subjects during sleep time. We conclude from this study that the proposed cuff-less PTT-based BP monitoring system has potential to be a less intrusive alternative to standard oscillometric method for long-term overnight BP monitoring.
authors.forename: Yali
authors.initials: Y
authors.lastname: Zheng
authors.forename: Bryan P
authors.initials: BP
authors.lastname: Yan
authors.forename: Yuanting
authors.initials: Y
authors.lastname: Zhang
authors.forename: C M
authors.initials: CM
authors.lastname: Yu
authors.forename: Carmen C Y
authors.initials: CC
authors.lastname: Poon
mesh_terms: D000328:Adult; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory / Q000295:instrumentation* / Q000379:methods; D004562:Electrocardiography / Q000295:instrumentation; D005260:Female; D006801:Humans; D008297:Male; D009991:Oscillometry / Q000295:instrumentation; D063177:Pulse Wave Analysis; D012890:Sleep; D055815:Young Adult