title: Thermal amplitude test.
abstract: The thermal amplitude test is performed to determine the reactivity of a cold autoantibody at varying temperatures: 4° C, 22° C, 30° C, and 37° C. Cold autoantibodies that are reactive at temperatures greater than 30° C have the potential to be clinically significant regardless of the antibody titer. Cold antibodies that are reactive at temperatures less than 30° C are not considered to be clinically significant.
authors.affiliation: DO (corresponding author), Medical Director.
authors.forename: Courtney
authors.initials: C
authors.lastname: Hopkins
authors.forename: Tiffany K
authors.initials: TK
authors.lastname: Walters
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood*; D001323:Autoantibodies / Q000097:blood*; D003080:Cold Temperature; D006801:Humans; D007159:Immunologic Tests / Q000379:methods*
chemical_list: D001323:Autoantibodies