title: Towards a physiological signal-based access solution for a non-verbal adolescent with severe and multiple disabilities.
abstract: OBJECTIVE
  To find physiologically arousing stimuli and labile physiological channels in a non-verbal adolescent with severe and multiple congenital disabilities, who did not have a reliable means of communication.
  
  
  METHODS
  The client was repeatedly presented with visual and audiovisual stimuli, representing variations of six contextual factors over three sessions in a one month period. For each stimulus, reactions were detected in the client's four peripheral autonomic nervous system signals using a rule-based classification algorithm.
  
  
  RESULTS
  During the presentation of audiovisual stimuli, the number of physiological reactions significantly differed from that observed in baseline (χ(2) = 3.93, p = 0.0476). Aural stimuli articulated in an unfamiliar voice, and aural stimuli containing anticipatory patterns were also physiologically arousing. Fingertip temperature was the client's most labile physiological signal.
  
  
  CONCLUSIONS
  The results of this case study suggest that physiological data may complement caregiver acumen in deciphering the reactions of non-verbal clients with severe and multiple disabilities.
authors.affiliation: David Geffen School of Medicine, University of California Los Angeles , Los Angeles, CA , USA .
authors.forename: Negar
authors.initials: N
authors.lastname: Memarian
authors.forename: Stefanie
authors.initials: S
authors.lastname: Blain-Moraes
authors.forename: Tom
authors.initials: T
authors.lastname: Chau
mesh_terms: D000015:Abnormalities, Multiple / Q000534:rehabilitation*; D000293:Adolescent; D001143:Arousal; D001341:Autonomic Nervous System / Q000473:pathology; D017028:Caregivers; D002547:Cerebral Palsy / Q000534:rehabilitation*; D003142:Communication; D003143:Communication Devices for People with Disabilities; D004867:Equipment Design; D005385:Fingers; D006339:Heart Rate; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D011782:Quadriplegia / Q000534:rehabilitation*; D056152:Respiratory Rate; D012815:Signal Processing, Computer-Assisted; D012881:Skin Temperature
keywords: Access pathway; arousal; people with severe disabilities; physiological signals