title: Macrophages and transplant rejection: a novel future target?
abstract: In this issue of Transplantation, Ma et al. describe the protective effect of administering the c-fms kinase inhibitor upon cellular rejection, suggesting an important pathogenic role for macrophages. In contrast, no effect upon the development of humerol rejection was evident. The role of macrophages in rejection is discussed.
authors.affiliation: MRC Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK.
authors.forename: George H
authors.initials: GH
authors.lastname: Tse
authors.forename: Jeremy
authors.initials: J
authors.lastname: Hughes
mesh_terms: D000818:Animals; D006084:Graft Rejection / Q000276:immunology*; D007111:Immunity, Cellular; D056724:Immunity, Humoral; D016030:Kidney Transplantation / Q000009:adverse effects*; D008264:Macrophages / Q000276:immunology*