title: The effect of prenatal exposure to 900-MHz electromagnetic field on the 21-old-day rat testicle.
abstract: The aim of this study was to investigate the effect of exposure to a 900-MHz electromagnetic field (EMF) in the prenatal term on the 21-old-day rat testicle. Pregnant rats were divided into control (CG) and EMF (EMFG) groups. EMFG was exposed to 900-MHz EMF during days 13-21 of pregnancy. Newborn CG rats were obtained from the CG and newborn EMFG (NEMFG) rats from the EMFG. Testicles were extracted at postnatal day 21. Lipid peroxidation and DNA oxidation levels, apoptotic index and histopathological damage scores were compared. NEMFG rats exhibited irregularities in seminiferous tubule basal membrane and epithelium, immature germ cells in the lumen, and a decreased diameter in seminiferous tubules and thickness of epithelium. Apoptotic index, lipid peroxidation and DNA oxidation were higher in NEMFG rats than in NCG. 21-day-old rat testicles exposed to 900-MHz EMF in the prenatal term may be adversely affected, and this effect persists after birth.
authors.affiliation: Department of Histology and Embryology, School of Medicine, Karadeniz Technical University, Trabzon 61080, Turkey.
authors.forename: Hatice
authors.initials: H
authors.lastname: Hancı
authors.forename: Ersan
authors.initials: E
authors.lastname: Odacı
authors.forename: Haydar
authors.initials: H
authors.lastname: Kaya
authors.forename: Yüksel
authors.initials: Y
authors.lastname: Aliyazıcıoğlu
authors.forename: İbrahim
authors.initials: İ
authors.lastname: Turan
authors.forename: Selim
authors.initials: S
authors.lastname: Demir
authors.forename: Serdar
authors.initials: S
authors.lastname: Çolakoğlu
mesh_terms: D000818:Animals; D017209:Apoptosis; D004247:DNA / Q000378:metabolism; D004574:Electromagnetic Fields / Q000009:adverse effects*; D005260:Female; D015227:Lipid Peroxidation; D008297:Male; D010084:Oxidation-Reduction; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D013737:Testis / Q000473:pathology*
chemical_list: D004247:DNA
keywords: Apoptosis; Electromagnetic field; Rat; Testicle