title: Stroke by carotid artery complete occlusion in Kawasaki disease: case report and review of literature.
abstract: BACKGROUND
  Kawasaki disease is an acute and time-limited systemic vasculitis primarily affecting young children.
  
  
  METHODS
  We describe an 18-month-old girl with Kawasaki disease who developed cerebral infarction following complete occlusion of her right internal carotid artery.
  
  
  RESULTS
  The occlusion occurred 10 days after the onset of fever, while she was on high-dose aspirin, and the day after she received intravenous immunoglobulin treatment. We present the first literature review on this very rare complication.
  
  
  CONCLUSIONS
  Stroke is a rare neurological complication in Kawasaki disease. Optimal treatment should be begun as soon as possible after diagnosis. Intravenous immunoglobulins seem to reduce the cerebrovascular complications, but evaluation of hydration status is strongly recommended before performing such treatment.
authors.affiliation: Hospices Civils de Lyon, HFME, Service de Neuropédiatrie, Bron, France; Université Claude Bernard Lyon 1, Lyon, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Sabatier
authors.forename: Stéphane
authors.initials: S
authors.lastname: Chabrier
authors.forename: Amandine
authors.initials: A
authors.lastname: Brun
authors.forename: Laure
authors.initials: L
authors.lastname: Hees
authors.forename: Anne
authors.initials: A
authors.lastname: Cheylus
authors.forename: Randy
authors.initials: R
authors.lastname: Gollub
authors.forename: Nouchine
authors.initials: N
authors.lastname: Hadjikhani
authors.forename: Jian
authors.initials: J
authors.lastname: Kong
authors.forename: Vincent
authors.initials: V
authors.lastname: des Portes
authors.forename: Daniel
authors.initials: D
authors.lastname: Floret
authors.forename: Aurore
authors.initials: A
authors.lastname: Curie
mesh_terms: D002343:Carotid Artery, Internal / Q000473:pathology*; D016893:Carotid Stenosis / Q000150:complications*; D002544:Cerebral Infarction / Q000209:etiology; D002941:Circle of Willis / Q000000981:diagnostic imaging; D016206:Databases, Bibliographic / Q000706:statistics & numerical data; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D007223:Infant; D018810:Magnetic Resonance Angiography; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications*; D011859:Radiography; D020521:Stroke / Q000209:etiology*
keywords: Kawasaki disease; carotid artery occlusion; immunoglobulin; infant; stroke