title: In vitro activities of eight antifungal drugs against 106 waterborne and cutaneous exophiala species.
abstract: The in vitro activities of eight antifungal drugs against 106 clinical and environmental isolates of waterborne and cutaneous Exophiala species were tested. The MICs and minimum effective concentrations for 90% of the strains tested (n = 106) were, in increasing order, as follows: posaconazole, 0.063 μg/ml; itraconazole, 0.25 μg/ml; micafungin, 1 μg/ml; voriconazole, 2 μg/ml; isavuconazole, 4 μg/ml; caspofungin, 8 μg/ml; amphotericin B, 16 μg/ml; fluconazole, 64 μg/ml.
authors.affiliation: Department of Parasitology and Mycology, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: M J
authors.initials: MJ
authors.lastname: Najafzadeh
authors.forename: M
authors.initials: M
authors.lastname: Saradeghi Keisari
authors.forename: V A
authors.initials: VA
authors.lastname: Vicente
authors.forename: P
authors.initials: P
authors.lastname: Feng
authors.forename: S A A
authors.initials: SA
authors.lastname: Shamsian
authors.forename: A
authors.initials: A
authors.lastname: Rezaei-Matehkolaei
authors.forename: G S
authors.initials: GS
authors.lastname: de Hoog
authors.forename: I
authors.initials: I
authors.lastname: Curfs-Breuker
authors.forename: J F
authors.initials: JF
authors.lastname: Meis
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology*; D000077336:Caspofungin; D054714:Echinocandins / Q000494:pharmacology; D005093:Exophiala / Q000187:drug effects*; D015725:Fluconazole / Q000494:pharmacology; D017964:Itraconazole / Q000494:pharmacology; D055666:Lipopeptides / Q000494:pharmacology; D000077551:Micafungin; D008826:Microbial Sensitivity Tests; D009570:Nitriles / Q000494:pharmacology; D011725:Pyridines / Q000494:pharmacology; D011743:Pyrimidines / Q000494:pharmacology; D014230:Triazoles / Q000494:pharmacology; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D009570:Nitriles; D011725:Pyridines; D011743:Pyrimidines; D014230:Triazoles; D017964:Itraconazole; C508735:isavuconazole; C101425:posaconazole; D000666:Amphotericin B; D015725:Fluconazole; D000077336:Caspofungin; D065819:Voriconazole; D000077551:Micafungin