title: Implantable acceleration plethysmography for blood pressure determination.
abstract: This paper presents an implantable accelerometer which detects plethysmograms directly at an artery. The sensor provides a new method for continuous blood pressure monitoring. In vivo measurements indicate that the accelerometer is well suited for determining the Pulse Transit Time (PTT) and the Reflected Wave Transit Time (RWTT). Both parameters show a high correlation with the systolic blood pressure. By varying the blood pressure, it was seen that RWTT more closely agrees with theory than PTT. Through several blood pressure sweeps the RWTT, as detected by the accelerometer, coincided very well with the systolic blood pressure, with a correlation coefficient of 0.96 and mean deviation of 4.3% for 1800 pulses.
authors.forename: Michael
authors.initials: M
authors.lastname: Theodor
authors.forename: Dominic
authors.initials: D
authors.lastname: Ruh
authors.forename: Katharina
authors.initials: K
authors.lastname: Förster
authors.forename: Claudia
authors.initials: C
authors.lastname: Heilmann
authors.forename: Friedhelm
authors.initials: F
authors.lastname: Beyersdorf
authors.forename: Hans
authors.initials: H
authors.lastname: Zappe
authors.forename: Andreas
authors.initials: A
authors.lastname: Seifert
mesh_terms: D000054:Acceleration; D000818:Animals; D001011:Aorta / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D001795:Blood Pressure Determination / Q000379:methods*; D004562:Electrocardiography; D008297:Male; D010991:Plethysmography / Q000379:methods*; D019736:Prostheses and Implants; D063177:Pulse Wave Analysis; D011817:Rabbits; D012815:Signal Processing, Computer-Assisted