title: Nasal carriage of 200 patients with nasal bone fracture in Korea.
abstract: BACKGROUND
  Pathogens in the nasal cavity during nasal surgery could lead to a systemic infectious condition, such as bacteremia, nosocomial infection, or toxic shock syndrome. However, there is no research about the prevalence of nasal carriage in patients with nasal bone fracture.
  
  
  METHODS
  This was a prospective, double-blind, randomized study about the rate of nasal carriage in 200 patients with nasal bone fracture in Korea. Nasal secretions were taken from both the middle nasal meatus and colonized. All analyses were carried out using SPSS software.
  
  
  RESULTS
  Pathogens were identified in 178 of the 200 cases. Coagulase-negative staphylococci (CNS) were the most cultured bacteria in 127 (66.84%) of the 190 total patients after excluding 10 cases of contaminated samples, and methicillin-resistant coagulase-negative staphylococci (MRCNS) were found in 48 (25.26%). Staphylococcus aureus was the second most identified pathogen, found in 36 (18.95%), followed by 7 cases (3.68%) of methicillin-resistant Staphylococcus aureus (MRSA). The prevalence rate of MRSA in the females was higher than that in the males (RR=4.70; 95% CI, 1.09-20.18), but other demographic factors had no effect on the prevalence rate of MRSA and MRCNS.
  
  
  CONCLUSIONS
  The prevalence rate of these pathogens in patients with nasal bone fracture in Korea was similar to other reports. However, few studies have addressed the prevalence rate of CNS and MRCNS in accordance with risk factors or the change in prevalence according to specific prophylaxis against infectious complications. Additional research is needed on the potential connections between clinical factors and microbiological data.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Jun Wook
authors.initials: JW
authors.lastname: Lee
authors.forename: Young Joon
authors.initials: YJ
authors.lastname: Kim
authors.forename: Hoon
authors.initials: H
authors.lastname: Kim
authors.forename: Sang Hyun
authors.initials: SH
authors.lastname: Nam
authors.forename: Bo Moon
authors.initials: BM
authors.lastname: Shin
authors.forename: Young Woong
authors.initials: YW
authors.lastname: Choi
keywords: Methicillin-resistant Staphylococcus aureus; Nasal bone; Staphylococcus aureus