title: Review of spectral imaging technology in biomedical engineering: achievements and challenges.
abstract: Spectral imaging is a technology that integrates conventional imaging and spectroscopy to get both spatial and spectral information from an object. Although this technology was originally developed for remote sensing, it has been extended to the biomedical engineering field as a powerful analytical tool for biological and biomedical research. This review introduces the basics of spectral imaging, imaging methods, current equipment, and recent advances in biomedical applications. The performance and analytical capabilities of spectral imaging systems for biological and biomedical imaging are discussed. In particular, the current achievements and limitations of this technology in biomedical engineering are presented. The benefits and development trends of biomedical spectral imaging are highlighted to provide the reader with an insight into the current technological advances and its potential for biomedical research.
authors.affiliation: East China Normal University, Key Laboratory of Polar Materials and Devices, Shanghai 200241, ChinabColumbia University, Department of Psychiatry, Brain Imaging Lab, New York 10032.
authors.forename: Qingli
authors.initials: Q
authors.lastname: Li
authors.forename: Xiaofu
authors.initials: X
authors.lastname: He
authors.forename: Yiting
authors.initials: Y
authors.lastname: Wang
authors.forename: Hongying
authors.initials: H
authors.lastname: Liu
authors.forename: Dongrong
authors.initials: D
authors.lastname: Xu
authors.forename: Fangmin
authors.initials: F
authors.lastname: Guo
mesh_terms: D000818:Animals; D001698:Biomedical Engineering / Q000379:methods*; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D013057:Spectrum Analysis / Q000379:methods*