title: Comparison of logistic regression and neural network classifiers in the detection of hard exudates in retinal images.
abstract: Diabetic Retinopathy (DR) is a common cause of visual impairment in industrialized countries. Automatic recognition of DR lesions in retinal images can contribute to the diagnosis and screening of this disease. The aim of this study is to automatically detect one of these lesions: hard exudates (EXs). Based on their properties, we extracted a set of features from image regions and selected the subset that best discriminated between EXs and the retinal background using logistic regression (LR). The LR model obtained, a multilayer perceptron (MLP) classifier and a radial basis function (RBF) classifier were subsequently used to obtain the final segmentation of EXs. Our database contained 130 images with variable color, brightness, and quality. Fifty of them were used to obtain the training examples. The remaining 80 images were used to test the performance of the method. The highest statistics were achieved for MLP or RBF. Using a lesion based criterion, our results reached a mean sensitivity of 95.9% (MLP) and a mean positive predictive value of 85.7% (RBF). With an image-based criterion, we achieved a 100% mean sensitivity, 87.5% mean specificity and 93.8% mean accuracy (MLP and RBF).
authors.forename: Maria
authors.initials: M
authors.lastname: Garcia
authors.forename: Carmen
authors.initials: C
authors.lastname: Valverde
authors.forename: Maria I
authors.initials: MI
authors.lastname: Lopez
authors.forename: Jesus
authors.initials: J
authors.lastname: Poza
authors.forename: Roberto
authors.initials: R
authors.lastname: Hornero
mesh_terms: D000465:Algorithms; D003116:Color; D003930:Diabetic Retinopathy / Q000175:diagnosis / Q000473:pathology; D005122:Exudates and Transudates / Q000166:cytology*; D006801:Humans; D016015:Logistic Models; D016571:Neural Networks, Computer; D012160:Retina / Q000473:pathology*