title: Phenol ring nitration induced by the unprecedented reduction of the Cu(II) centre by nitrogen dioxide.
abstract: Nitrogen dioxide (˙NO2) induces tyrosine nitration through a radical mechanism in biological systems. Two copper(II) complexes, 1 and 2, with ligands L₁ and L₂ [L₁ = 2,4-di-tert-butyl-6-(((2-(dimethylamino)ethyl)(isopropyl)amino)methyl)phenol; L₂ = 6,6'-(((2-(dimethylamino)ethyl)azanediyl)bis(methylene))bis(2,4-di-tert-butylphenol)], respectively, have been made to react with ˙NO2. In both cases, the reduction of the copper(II) center was observed in the presence of ˙NO2 which induces phenol ring nitration through nitronium ion (NO2(+)) formation.
authors.forename: Vikash
authors.initials: V
authors.lastname: Kumar
authors.forename: Aswini
authors.initials: A
authors.lastname: Kalita
authors.forename: Biplab
authors.initials: B
authors.lastname: Mondal
mesh_terms: D056831:Coordination Complexes / Q000737:chemistry; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D007477:Ions / Q000737:chemistry; D008968:Molecular Conformation; D009574:Nitro Compounds / Q000737:chemistry; D009585:Nitrogen Dioxide / Q000737:chemistry*; D010084:Oxidation-Reduction; D019800:Phenol / Q000737:chemistry*; D026361:Reactive Nitrogen Species / Q000737:chemistry
chemical_list: D056831:Coordination Complexes; D007477:Ions; D009574:Nitro Compounds; D026361:Reactive Nitrogen Species; D019800:Phenol; D003300:Copper; D009585:Nitrogen Dioxide