title: Immunoglobulin g4-related disease presenting as an obstructing tracheal mass: consideration of surgical indications.
abstract: Immunoglobulin G4 (IgG4)-related disease is increasingly recognized in many organs; however, none are described in detail is the trachea. In addition, the role of surgical intervention in the disease has yet to be fully defined. We describe a patient with IgG4-related airway disease presenting as a low tracheal mass, which was treated with tracheal resection and reconstruction. This novel presentation of the disease highlights the importance of including IgG4-related disease in the differential diagnosis of tracheal masses. Further, possible indications for surgical therapy are considered. As the full clinical spectrum of IgG4-related disease continues to evolve, so too must approaches to disease management.
authors.affiliation: Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, Massachusetts. Electronic address: ekobraei@partners.org.
authors.forename: Edward M
authors.initials: EM
authors.lastname: Kobraei
authors.affiliation: Division of Thoracic Surgery, Massachusetts General Hospital, Boston, Massachusetts.
authors.forename: Tae H
authors.initials: TH
authors.lastname: Song
authors.affiliation: Division of Thoracic Surgery, Massachusetts General Hospital, Boston, Massachusetts.
authors.forename: Douglas J
authors.initials: DJ
authors.lastname: Mathisen
authors.affiliation: Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.
authors.forename: Vikram
authors.initials: V
authors.lastname: Deshpande
authors.affiliation: Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.
authors.forename: Eugene J
authors.initials: EJ
authors.lastname: Mark
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007074:Immunoglobulin G; D010265:Paraproteinemias / Q000150:complications* / Q000175:diagnosis; D014135:Tracheal Stenosis / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery
chemical_list: D007074:Immunoglobulin G
keywords: 15