title: Lack of correlation between preoperative and intraoperative liver hemodynamics: a descriptive analysis.
abstract: BACKGROUND
  Adult living-donor liver transplantation recipients undergo important hemodynamic changes during the procedure, which in turn have proven to be of the upmost importance when dealing with small grafts, to avoid the so-called "small-for-size" syndrome.
  
  
  METHODS
  Back in 2003, we started a hemodynamic monitoring protocol in adult living-donor liver transplantation recipients, which evaluated the hemodynamic status of the patient 24 hr before, during, and 3 days after transplantation. We analyzed the correlation between the same hemodynamic variables measured in the hemodynamic laboratory and those taken in the operating room.
  
  
  RESULTS
  With the exception of cardiac index and indexed systemic vascular resistance, all the other hepatic and systemic hemodynamic parameters measured before and during the intervention, as well as during and after the intervention, showed a lack of correlation.
  
  
  CONCLUSIONS
  The observed lack of correlation may happen due to many factors, such as the influence of vasoactive and anesthetic drugs, total muscular relaxation, or the presence of an open abdomen. As a result, a direct comparison between hemodynamic values should only be done when measured in the same conditions.
authors.affiliation: 1 Hepatobiliopancreatic Surgery and Transplantation Unit, Hospital Clínic de Barcelona, Barcelona, Spain. 2 Hepatology, Liver Hemodynamic Unit, Hospital Clínic de Barcelona, Barcelona, Spain. 3 Anesthesiology Unit, Hospital Clínic de Barcelona, Barcelona, Spain. 4 Address correspondence to: Juan Carlos García-Valdecasas, M.D., Ph.D., Cirurgia General i Digestiva, Unitat de Cirurgia HBP i Transplantament, ICMDM, Hospital Clínic de Barcelona, Barcelona, Spain.
authors.forename: Santiago
authors.initials: S
authors.lastname: Sánchez-Cabús
authors.forename: Juan G
authors.initials: JG
authors.lastname: Abraldes
authors.forename: Pilar
authors.initials: P
authors.lastname: Taurá
authors.forename: David
authors.initials: D
authors.lastname: Calatayud
authors.forename: Constantino
authors.initials: C
authors.lastname: Fondevila
authors.forename: José
authors.initials: J
authors.lastname: Fuster
authors.forename: Joana
authors.initials: J
authors.lastname: Ferrer
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: García-Pagán
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: García-Valdecasas
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006439:Hemodynamics; D006801:Humans; D016014:Linear Models; D008099:Liver / Q000098:blood supply* / Q000601:surgery*; D008102:Liver Circulation; D016031:Liver Transplantation / Q000009:adverse effects / Q000379:methods; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D059035:Perioperative Period; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D013997:Time Factors; D016896:Treatment Outcome