title: Evaluation of the in vitro anti-atherogenic properties of lipid fractions of olive pomace, olive pomace enriched fish feed and gilthead sea bream (Sparus aurata) fed with olive pomace enriched fish feed.
abstract: Given the pivotal role of Platelet-Activating-Factor (PAF) in atherosclerosis and the cardio-protective role of PAF-inhibitors derived from olive pomace, the inclusion of olive pomace in fish feed has been studied for gilthead sea bream (Sparus aurata). The aim of the current research was to elucidate the anti-atherogenic properties of specific HPLC lipid fractions obtained from olive pomace, olive pomace enriched fish feed and fish fed with the olive pomace enriched fish feed, by evaluating their in vitro biological activity against washed rabbit platelets. This in vitro study underlines that olive pomace inclusion in fish feed improves the nutritional value of both fish feed and fish possibly by enriching the marine lipid profile of gilthead sea bream (Sparus aurata) with specific bioactive lipid compounds of plant origin.
authors.affiliation: Laboratory of Food Chemistry, Faculty of Chemistry, School of Sciences, National and Kapodistrian University of Athens, Athens 15771, Greece. cnasopoulou@chem.uoa.gr.
authors.forename: Constantina
authors.initials: C
authors.lastname: Nasopoulou
authors.forename: Vassiliki
authors.initials: V
authors.lastname: Gogaki
authors.forename: Giorgos
authors.initials: G
authors.lastname: Stamatakis
authors.forename: Leonidas
authors.initials: L
authors.lastname: Papaharisis
authors.forename: Constantinos A
authors.initials: CA
authors.lastname: Demopoulos
authors.forename: Ioannis
authors.initials: I
authors.lastname: Zabetakis
mesh_terms: D000821:Animal Feed; D000818:Animals; D050197:Atherosclerosis / Q000188:drug therapy*; D005399:Fishes / Q000378:metabolism*; D008055:Lipids / Q000737:chemistry*; D000069463:Olive Oil; D010938:Plant Oils / Q000737:chemistry* / Q000494:pharmacology*; D021541:Sea Bream / Q000378:metabolism*
chemical_list: D008055:Lipids; D000069463:Olive Oil; D010938:Plant Oils