title: [Prophylactic use of VFS in patients with coronary artery disease in the perioperative coronary artery bypass grafting].
abstract: Tachyarrhythmias (TA) - dangerous postoperative complications of coronary artery bypass grafting, threatening the lives of patients and found, according to different authors, in 13-40% of cases. VFS - an antiarrhythmic drug that belongs to a class 1C, is effective in the treatment and prevention of a variety of cardiac arrhythmias. The aim of the work was to study the clinical efficacy of VFS CHD patients with a history of tachyarrhythmias during the perioperative period of coronary bypass surgery, as well as its comparison with other antiarrhythmic drug (amiodarone). Clinical efficacy was evaluated in 218 patients with coronary heart disease at baseline with a history of tachyarrhythmia (paroxysmal atrial fibrillation or premature ventricular high grade (IV and V class on classification of Lown B. and Wolf M. in the modification of Ryan M.). Shown that the VFS is more effective than amiodarone, both in paroxysmal atrial fibrillation and ventricular arrhythmias when high gradation.
authors.affiliation: Republican Cardiological Dispensary, ul. St. Kuvykina 96, 450106 Ufa, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Plechev
authors.forename: Sh Z
authors.initials: ShZ
authors.lastname: Zagidullin
authors.forename: V M
authors.initials: VM
authors.lastname: Iunusov
authors.forename: I G
authors.initials: IG
authors.lastname: Zubareva
authors.forename: I E
authors.initials: IE
authors.lastname: Nikolaeva
mesh_terms: D000157:Aconitine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D000638:Amiodarone / Q000008:administration & dosage / Q000009:adverse effects; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000009:adverse effects; D018890:Chemoprevention / Q000379:methods; D057186:Comparative Effectiveness Research; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D003324:Coronary Artery Disease / Q000601:surgery; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019990:Perioperative Care / Q000379:methods; D011183:Postoperative Complications / Q000503:physiopathology / Q000517:prevention & control*; D012189:Retrospective Studies; D013610:Tachycardia / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D016896:Treatment Outcome
chemical_list: D000889:Anti-Arrhythmia Agents; C051402:allapinin; D000638:Amiodarone; D000157:Aconitine