title: Is photodynamic therapy with adjunctive non-surgical periodontal therapy effective in the treatment of periodontal disease under immunocompromised conditions?
abstract: The aim was to assess whether or not photodynamic therapy (PDT) with adjunctive scaling-and-root-planing (SRP) is effective in the treatment of periodontitis under immunocompromised conditions. PubMed/Medline and Google-Scholar databases were searched from 1967 to May 2013 using various key words. Six studies (five experimental and one clinical) were included. In the clinical study, SRP with PDT was reported to be ineffective in treating chronic periodontitis in T2DM patients. All experimental studies reported significantly less bone loss in periodontal defects treated with SRP+PDT than those treated with SRP alone. Efficacy of PDT+SRP in the treatment of periodontal disease under immunocompromised conditions remains unclear.
authors.affiliation: Engineer Abdullah Bugshan Research Chair for Growth Factors and Bone Regeneration, 3D Imaging and Biomechanical Laboratory, College Applied Medical Sciences, King Saud University, Riyadh, KSA.
authors.forename: Fawad
authors.initials: F
authors.lastname: Javed
authors.forename: Talat
authors.initials: T
authors.lastname: Qadri
authors.forename: Hameeda Bashir
authors.initials: HB
authors.lastname: Ahmed
authors.forename: Khalid
authors.initials: K
authors.lastname: Al-Hezaimi
authors.forename: Francis Esmonde
authors.initials: FE
authors.lastname: Corbet
authors.forename: Georgios E
authors.initials: GE
authors.lastname: Romanos
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D012534:Dental Scaling; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D010510:Periodontal Diseases / Q000188:drug therapy*; D010512:Periodontal Index; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use; D016745:Root Planing; D016896:Treatment Outcome
chemical_list: D017319:Photosensitizing Agents