title: yApoptosis: yeast apoptosis database.
abstract: In the past few years, programmed cell death (PCD) has become a popular research area due to its fundamental aspects and its links to human diseases. Yeast has been used as a model for studying PCD, since the discovery of morphological markers of apoptotic cell death in yeast in 1997. Increasing knowledge in identification of components and molecular pathways created a need for organization of information. To meet the demands from the research community, we have developed a curated yeast apoptosis database, yApoptosis. The database structurally collects an extensively curated set of apoptosis, PCD and related genes, their genomic information, supporting literature and relevant external links. A web interface including necessary functions is provided to access and download the data. In addition, we included several networks where the apoptosis genes or proteins are involved, and present them graphically and interactively to facilitate rapid visualization. We also promote continuous inputs and curation by experts. yApoptosis is a highly specific resource for sharing information online, which supports researches and studies in the field of yeast apoptosis and cell death. DATABASE URL: http://www.ycelldeath.com/yapoptosis/.
authors.affiliation: Department of Chemical and Biological Engineering, Chalmers University of Technology, Kemivägen 10, 41296, Gothenburg, Sweden, Department of Mathematics, Chalmers University of Technology, Chalmers tvärgata 3, 41296, Gothenburg, Sweden, Department of Mathematics, University of Gothenburg, Chalmers tvärgata 3, 41296, Gothenburg, Sweden and Fine Chemicals and Biocatalysis Research, BASF SE, GVF/D - A030, 67056 Ludwigshafen, Germany.
authors.forename: Kwanjeera
authors.initials: K
authors.lastname: Wanichthanarak
authors.forename: Marija
authors.initials: M
authors.lastname: Cvijovic
authors.forename: Andrea
authors.initials: A
authors.lastname: Molt
authors.forename: Dina
authors.initials: D
authors.lastname: Petranovic
mesh_terms: D017209:Apoptosis / Q000235:genetics; D019992:Databases as Topic; D053263:Gene Regulatory Networks / Q000235:genetics; D005800:Genes, Fungal / Q000235:genetics; D006801:Humans; D020407:Internet; D012441:Saccharomyces cerevisiae / Q000166:cytology* / Q000235:genetics; D014584:User-Computer Interface