title: Localization of brachytherapy seeds in MRI by deconvolution.
abstract: MRI has the potential to be used as a preferred imaging method for brachytherapy during the seed insertion and post-surgery evaluation. However, the brachytherapy seeds usually appear dark in the MRI magnitude images. Previously, we have developed a method based on susceptibility mapping to generate positive contrast of the seeds, which allows improved seed localization. In this paper, we propose a new method to localize the seeds by deconvolution using a seed kernel (i.e. the calculated magnetic field surrounding a seed). The deconvolution is solved using a regularized L1 minimization. Results from simulated and experimental data sets show that the seeds can be identified and localized using the proposed method more precisely.
authors.forename: Ying
authors.initials: Y
authors.lastname: Dong
authors.forename: Zheng
authors.initials: Z
authors.lastname: Chang
authors.forename: Gregory
authors.initials: G
authors.lastname: Whitehead
authors.forename: Jim
authors.initials: J
authors.lastname: Ji
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D003198:Computer Simulation; D003287:Contrast Media; D006801:Humans; D007091:Image Processing, Computer-Assisted; D060328:Magnetic Phenomena; D008279:Magnetic Resonance Imaging / Q000379:methods*
chemical_list: D003287:Contrast Media