title: Highly enantioselective iron(II)-catalyzed opening reaction of aromatic meso-epoxides with indoles.
abstract: A highly enantioselective method for the catalytic cis-stilbene oxide opening reaction with indole derivatives was developed. The scope of the reaction was studied with a selection of aromatic meso-epoxides and various indoles, and the desired 2-(indol-3-yl)ethanol derivatives were obtained in good to excellent yields with excellent enantioselectivities (from 96 to >99% ee).
authors.affiliation: Département de chimie, Université Laval, 1045 avenue de la Médecine, Québec (Québec) G1V 0A6, Canada. thierry.ollevier@chm.ulaval.ca.
authors.forename: Baptiste
authors.initials: B
authors.lastname: Plancq
authors.forename: Mathieu
authors.initials: M
authors.lastname: Lafantaisie
authors.forename: Simon
authors.initials: S
authors.lastname: Companys
authors.forename: Cendrella
authors.initials: C
authors.lastname: Maroun
authors.forename: Thierry
authors.initials: T
authors.lastname: Ollevier