title: Towards a smart Holter system with high performance analogue front-end and enhanced digital processing.
abstract: Multiple-lead dynamic ECG recorders (Holter) play an important role in the earlier detection of various cardiovascular diseases. In this paper, we present the first several steps towards a 12-lead Holter system with high-performance AFE (Analogue Front-End) and enhanced digital processing. The system incorporates an analogue front-end chip (ADS1298 from TI), which has not yet been widely used in most commercial Holter products. A highly-efficient data management module was designated to handle the data exchange between the ADS1298 and the microprocessor (STM32L151 from ST electronics). Furthermore, the system employs a Field Programmable Gate Array (Spartan-3E from Xilinx) module, on which a dedicated real-time 227-step FIR filter was executed to improve the overall filtering performance, since the ADS1298 has no high-pass filtering capability and only allows limited low-pass filtering. The Spartan-3E FPGA is also capable of offering further on-board computational ability for a smarter Holter. The results indicate that all functional blocks work as intended. In the future, we will conduct clinical trials and compare our system with other state-of-the-arts.
authors.forename: Leilei
authors.initials: L
authors.lastname: Du
authors.forename: Yan
authors.initials: Y
authors.lastname: Yan
authors.forename: Wenxian
authors.initials: W
authors.lastname: Wu
authors.forename: Qiujun
authors.initials: Q
authors.lastname: Mei
authors.forename: Yu
authors.initials: Y
authors.lastname: Luo
authors.forename: Yang
authors.initials: Y
authors.lastname: Li
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
mesh_terms: D000465:Algorithms; D003201:Computers; D004562:Electrocardiography / Q000295:instrumentation* / Q000379:methods; D004566:Electrodes; D004867:Equipment Design; D006801:Humans; D008838:Microcomputers; D008991:Monitoring, Physiologic / Q000295:instrumentation* / Q000379:methods; D012815:Signal Processing, Computer-Assisted; D012984:Software