title: [Arterial stiffness in patients with chronic obstructive lung disease in the presence and absence of ischemic heart disease].
abstract: Aim of the study was assessment of arterial stiffness in patients with chronic obstructive lung disease (COPD) with or without ischemic heart disease (IHD). We included in this open study 130 COPD patients older than 40 years (mean age 60.2+/-8.3 years). Patients with clinical signs of exacerbation of other severe chronic diseases were not included. Control group comprised 18 practically healthy volunteers older than 50years (mean age 56.9+/-7.2 years). Tensioclinic arteriograph was used for evaluation of arterial wall stiffness. The study revealed increase of pulse wave propagation velocity associated with elevation of augmentation indexes in COPD patients both with and without IHD as well as in patients with different degrees of 10-year risk of cardiovascular death. These changes can be considered as systemic manifestations of COPD possibly underlining interrelationships between COPD and cardiovascular diseases.
authors.affiliation: V.I. Razumovsky Saratov State Medical University, ul. Bolshaya Kazachya, 112, 410012 Saratov, Russia.
authors.forename: N A
authors.initials: NA
authors.lastname: Karoli
authors.forename: G R
authors.initials: GR
authors.lastname: Dolishniaia
authors.forename: A P
authors.initials: AP
authors.lastname: Rebrov
mesh_terms: D000368:Aged; D001011:Aorta / Q000503:physiopathology; D001916:Brachial Artery / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000401:mortality / Q000503:physiopathology; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications* / Q000503:physiopathology; D063177:Pulse Wave Analysis / Q000379:methods; D012307:Risk Factors; D012426:Russia; D016019:Survival Analysis; D014652:Vascular Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D059289:Vascular Stiffness