title: Focus on gastrointestinal and liver cancers.
abstract: Digestive cancers, such as colorectal cancer, gastric cancer and liver cancer, remain major threats to human health in coming decades and their epidemiology is under dynamic changes. Recent advances in genotyping and sequencing technologies together with other molecular and cellular biology techniques have led to a clearer delineation of the pathogenic mechanisms underlying genetic and environmental factors that contribute to digestive cancers. Such expansion of knowledge continues to fuel the development of novel biomarkers and therapeutics. In this special issue of Seminars in Cancer Biology, hot topics in basic and translational research of digestive cancers will be reviewed.
authors.affiliation: Institute of Digestive Diseases and State Key Laboratory of Digestive Diseases, Department of Medicine & Therapeutics, LKS Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China. Electronic address: wukakei@cuhk.edu.hk.
authors.forename: William K K
authors.initials: WK
authors.lastname: Wu
authors.forename: Joseph J Y
authors.initials: JJ
authors.lastname: Sung
mesh_terms: D005770:Gastrointestinal Neoplasms / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D008113:Liver Neoplasms / Q000453:epidemiology* / Q000209:etiology*
keywords: Colorectal cancer; Esophageal cancer; Gastric cancer; Liver cancer