title: Triple-phase helical computed tomography in dogs with hepatic masses.
abstract: The purpose of this study was to determine the utility of triple-phase helical computed tomography (CT) for differentiating canine hepatic masses. Seventy dogs with hepatic masses underwent triple-phase CT followed by surgical removal of the hepatic masses. Triple-phase helical CT scans for each dog included precontrast, arterial phase, portal venous phase, and delayed phase studies. The removed hepatic masses were histopathologically classified as hepatocellular carcinoma (n = 47), nodular hyperplasia (n = 14), and hepatic metastatic tumors (n = 9) in dogs. Of the 47 hepatocellular carcinomas, the most common CT findings included a heterogeneous pattern with hyper-, iso-, and hypoenhancement in both the arterial and portal venous phases (40/47, 85.1%). Of the 14 nodular hyperplasias, the most common CT findings were a homogeneous pattern with hyper- and isoenhancement in both the portal venous and delayed phases (13/14, 92.9%). Of nine hepatic metastatic tumors, the most common CT findings included a homogeneous hypoenhancement pattern in both the arterial and portal venous phases (8/9, 88.9%). In addition, 5 (55.6%) showed homogeneous hypoenhancement patterns in the delayed phase. Findings from our study indicated that triple-phase CT is a useful tool for preoperative differentiation of hepatocellular carcinoma, nodular hyperplasia, and hepatic metastatic tumors in dogs.
authors.affiliation: Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Kutara
authors.forename: Mamiko
authors.initials: M
authors.lastname: Seki
authors.forename: Chieko
authors.initials: C
authors.lastname: Ishikawa
authors.forename: Manabu
authors.initials: M
authors.lastname: Sakai
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Kagawa
authors.forename: Gentoku
authors.initials: G
authors.lastname: Iida
authors.forename: Kumiko
authors.initials: K
authors.lastname: Ishigaki
authors.forename: Kenji
authors.initials: K
authors.lastname: Teshima
authors.forename: Kazuya
authors.initials: K
authors.lastname: Edamura
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Nakayama
authors.forename: Kazushi
authors.initials: K
authors.lastname: Asano
mesh_terms: D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000662:veterinary; D004283:Dog Diseases / Q000000981:diagnostic imaging*; D004285:Dogs; D005260:Female; D006965:Hyperplasia / Q000000981:diagnostic imaging / Q000662:veterinary*; D008099:Liver / Q000000981:diagnostic imaging* / Q000473:pathology*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000662:veterinary*; D008297:Male; D036542:Tomography, Spiral Computed / Q000662:veterinary
keywords: computed tomography; dog; hepatic metastatic tumor; hepatocellular carcinoma; nodular hyperplasia