title: [Multiple-choice vocabulary intelligence test MWT in schizophrenia: valid measure of premorbid intelligence?].
abstract: OBJECTIVE
  The multiple-choice vocabulary intelligence test MWT (Mehrfachwahl-Wortschatz-Intelligenztest) as a measure of premorbid IQ is widely used in clinical practice and research in Germany. The study examined whether the MWT is actually insensitive to brain dysfunction and psychopathology in patients with schizophrenia.
  
  
  METHODS
  81 post-acute patients with schizophrenia and 27 matched healthy controls completed the MWT at two points in time. At baseline, we further applied a neuropsychological test battery and a psychopathology rating.
  
  
  RESULTS
  The multiple linear regression analysis showed that the MWT-IQ of patients is significantly confounded by neuropsychological dysfunctions and psychopathology. The repeated measurement ANOVA pointed to a significant recovery effect of the MWT-IQ during clinical remission in the patient group.
  
  
  CONCLUSIONS
  The results question the validity of the MWT as a measure of premorbid IQ in schizophrenia.
authors.affiliation: Universitätsklinik für Psychiatrie und Psychotherapie, Tübingen.
authors.forename: Andreas
authors.initials: A
authors.lastname: Wittorf
authors.affiliation: Klinik für Psychiatrie und Psychotherapie, Klinikum Fulda.
authors.forename: Georg
authors.initials: G
authors.lastname: Wiedemann
authors.affiliation: Universitätsklinik für Psychiatrie und Psychotherapie, Tübingen.
authors.forename: Stefan
authors.initials: S
authors.lastname: Klingberg
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007360:Intelligence; D007361:Intelligence Tests / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D062706:Prodromal Symptoms; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011594:Psychometrics / Q000706:statistics & numerical data; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000523:psychology*; D012016:Reference Values; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000175:diagnosis*; D012563:Schizophrenia, Paranoid / Q000175:diagnosis / Q000523:psychology; D012565:Schizophrenic Psychology; D014825:Vocabulary; D055815:Young Adult