title: Silver nanoparticles and mitochondrial interaction.
abstract: Nanotechnology has gone through a period of rapid growth, thus leading to the constant increase in the application of engineered nanomaterials in daily life. Several different types of nanoparticles have been engineered to be employed in a wide array of applications due to their high surface to volume ratio that leads to unique physical and chemical properties. So far, silver nanoparticles (AgNps) have been used in many more different medical devices than any other nanomaterial, mainly due to their antimicrobial properties. Despite the promising advantages posed by using AgNps in medical applications, the possible health effects associated with the inevitable human exposure to AgNps have raised concerns as to their use since a clear understanding of their specific interaction with biological systems has not been attained yet. In light of such consideration, aim of the present work is the morphological analysis of the intracellular behavior of AgNps with a diameter of 10 nm, with a special attention to their interaction with mitochondria.
authors.affiliation: Department of Biomedical Sciences, University of Padova, Via G. Colombo 3, 35100 Padova, Italy.
authors.forename: Eriberto
authors.initials: E
authors.lastname: Bressan
authors.forename: Letizia
authors.initials: L
authors.lastname: Ferroni
authors.forename: Chiara
authors.initials: C
authors.lastname: Gardin
authors.forename: Chiara
authors.initials: C
authors.lastname: Rigo
authors.forename: Michele
authors.initials: M
authors.lastname: Stocchero
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Vindigni
authors.forename: Warren
authors.initials: W
authors.lastname: Cairns
authors.forename: Barbara
authors.initials: B
authors.lastname: Zavan