title: Synthesis and evaluation of cyanine-styryl dyes with enhanced photostability for fluorescent DNA staining.
abstract: The photostability of cyanine-styryl dyes of the indole-quinolinium type can be significantly improved by structural variations while the excellent optical properties including the bright fluorescence in the presence of DNA can be maintained or even improved, too.
authors.affiliation: Institute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany. Wagenknecht@kit.edu.
authors.forename: Peggy R
authors.initials: PR
authors.lastname: Bohländer
authors.forename: Hans-Achim
authors.initials: HA
authors.lastname: Wagenknecht
mesh_terms: D052160:Benzothiazoles / Q000138:chemical synthesis / Q000737:chemistry*; D002232:Carbocyanines / Q000138:chemical synthesis / Q000737:chemistry*; D004247:DNA / Q000032:analysis* / Q000737:chemistry*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D055668:Photochemical Processes; D013050:Spectrometry, Fluorescence; D013194:Staining and Labeling / Q000379:methods*
chemical_list: D052160:Benzothiazoles; D002232:Carbocyanines; D005456:Fluorescent Dyes; C528472:benzothiazole styrylcyanine; D004247:DNA