title: Phylogenetic analysis and molecular characteristics of 17 porcine reproductive and respiratory syndrome virus isolates in Southern China from 2010 to 2011.
abstract: We analyzed the complete genomic sequences of 17 porcine reproductive and respiratory syndrome virus (PRRSV) isolates from Southern China obtained between 2010 and 2011 and found that four of seven isolates from 2011 were closely related to the JXA1-R strain (vaccine virus of JXA1). This close relationship between field isolates and China domestic vaccine viruses has not been reported to date. The occurrence of vaccine-like viruses potentially creates a threat for the pig breeding industry and brings difficulties for control of this disease.
authors.affiliation: MOA Key Laboratory of Animal Vaccine Development, Ministry of China, College of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Tianhe District, Guangzhou 510642, China.
authors.forename: Minze
authors.initials: M
authors.lastname: Zhang
authors.forename: Jiexiong
authors.initials: J
authors.lastname: Xie
authors.forename: Long
authors.initials: L
authors.lastname: Sun
authors.forename: Zhenpeng
authors.initials: Z
authors.lastname: Cao
authors.forename: Honglang
authors.initials: H
authors.lastname: Gu
authors.forename: Shengchao
authors.initials: S
authors.lastname: Deng
authors.forename: Yao
authors.initials: Y
authors.lastname: Chen
authors.forename: Zongxi
authors.initials: Z
authors.lastname: Cao
authors.forename: Fengfeng
authors.initials: F
authors.lastname: Tang
authors.forename: Shuo
authors.initials: S
authors.lastname: Su
authors.forename: Guihong
authors.initials: G
authors.lastname: Zhang
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002681:China / Q000453:epidemiology; D014644:Genetic Variation; D016679:Genome, Viral; D005838:Genotype; D008969:Molecular Sequence Data; D010802:Phylogeny; D019318:Porcine Reproductive and Respiratory Syndrome / Q000453:epidemiology / Q000276:immunology / Q000821:virology*; D019316:Porcine respiratory and reproductive syndrome virus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D013552:Swine; D014612:Vaccines / Q000235:genetics*
chemical_list: D014612:Vaccines
keywords: Complete genome; GP5; Nsp2; PRRSV