title: Eco-bio-social determinants for house infestation by non-domiciliated Triatoma dimidiata in the Yucatan Peninsula, Mexico.
abstract: BACKGROUND
  Chagas disease is a vector-borne disease of major importance in the Americas. Disease prevention is mostly limited to vector control. Integrated interventions targeting ecological, biological and social determinants of vector-borne diseases are increasingly used for improved control.
  
  
  RESULTS
  We investigated key factors associated with transient house infestation by T. dimidiata in rural villages in Yucatan, Mexico, using a mixed modeling approach based on initial null-hypothesis testing followed by multimodel inference and averaging on data from 308 houses from three villages. We found that the presence of dogs, chickens and potential refuges, such as rock piles, in the peridomicile as well as the proximity of houses to vegetation at the periphery of the village and to public light sources are major risk factors for infestation. These factors explain most of the intra-village variations in infestation.
  
  
  CONCLUSIONS
  These results underline a process of infestation distinct from that of domiciliated triatomines and may be used for risk stratification of houses for both vector surveillance and control. Combined integrated vector interventions, informed by an Ecohealth perspective, should aim at targeting several of these factors to effectively reduce infestation and provide sustainable vector control.
authors.affiliation: Laboratorio de Parasitología, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi", Universidad Autónoma de Yucatán, Mérida, Yucatán, Mexico ; Department of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, United States of America.
authors.forename: Eric
authors.initials: E
authors.lastname: Dumonteil
authors.forename: Pierre
authors.initials: P
authors.lastname: Nouvellet
authors.forename: Kathryn
authors.initials: K
authors.lastname: Rosecrans
authors.forename: Maria Jesus
authors.initials: MJ
authors.lastname: Ramirez-Sierra
authors.forename: Rubi
authors.initials: R
authors.lastname: Gamboa-León
authors.forename: Vladimir
authors.initials: V
authors.lastname: Cruz-Chan
authors.forename: Miguel
authors.initials: M
authors.lastname: Rosado-Vallado
authors.forename: Sébastien
authors.initials: S
authors.lastname: Gourbière
mesh_terms: D000818:Animals; D000829:Animals, Domestic; D017753:Ecosystem; D005191:Family Characteristics; D006801:Humans; D007303:Insect Vectors; D008800:Mexico; D012111:Residence Characteristics; D012424:Rural Population; D014224:Triatoma / Q000254:growth & development*