title: Acute retinal necrosis (ARN) in the context of neonatal HSV-2 exposure and subconjunctival dexamethasone: case report and literature review.
abstract: HSV-2 is an important cause of the acute retinal necrosis (ARN) syndrome in younger patients. We describe an atypical case of HSV-2 ARN in the context of neonatal exposure and subconjunctival steroid injection. Clinicians should be aware of the association of neonatal or congenital exposure to HSV-2 as a risk factor for this disease because early treatment may improve outcome and/or avoid involvement of both eyes.
authors.affiliation: Department of Ophthalmology, Royal Brisbane & Women's Hospital; ; School of Medicine, University of Queensland, Brisbane;
authors.forename: Lindsay
authors.initials: L
authors.lastname: McGrath
authors.forename: Marion
authors.initials: M
authors.lastname: Woods
authors.forename: Lawrence
authors.initials: L
authors.lastname: Lee
authors.forename: Diana
authors.initials: D
authors.lastname: Conrad
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D000998:Antiviral Agents / Q000627:therapeutic use; D003907:Dexamethasone / Q000009:adverse effects*; D015828:Eye Infections, Viral / Q000150:complications / Q000821:virology*; D005938:Glucocorticoids / Q000009:adverse effects*; D006561:Herpes Simplex / Q000175:diagnosis*; D018258:Herpesvirus 2, Human / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D011251:Pregnancy Complications, Infectious; D015882:Retinal Necrosis Syndrome, Acute / Q000821:virology*; D016896:Treatment Outcome; D014775:Virus Activation / Q000187:drug effects
chemical_list: D000893:Anti-Inflammatory Agents; D000998:Antiviral Agents; D005938:Glucocorticoids; D003907:Dexamethasone