title: Possible role of an error detection mechanism in brain processing of deception: PET-fMRI study.
abstract: To investigate brain maintenance of deliberate deception the positron emission tomography and the event related functional MRI studies were performed. We used an experimental paradigm that presupposed free choices between equally beneficial deceptive or honest actions. Experimental task simulated the "Cheat" card game which aims to defeat an opponent by sequential deceptive and honest claims. Results of both the PET and the fMRI studies revealed that execution of both deliberately deceptive and honest claims is associated with fronto-parietal brain network comprised of inferior and middle frontal gyri, precentral gyrus (BA 6), caudate nucleus, and inferior parietal lobule. Direct comparison between those claims, balanced in terms of decision making and action outcome (gain and losses), revealed activation of areas specifically associated with deception execution: precentral gyrus (BA 6), caudate nuclei, thalamus and inferior parietal lobule (BA 39/40). The obtained experimental data were discussed in relation to a possible role of an error detection system in processing deliberate deception.
authors.affiliation: N.P. Bechtereva Institute of the Human Brain, Russian Academy of Sciences, Academika Pavlova Street 9, St. Petersburg 197376, Russia. Electronic address: maxim.v.kireev@gmail.com.
authors.forename: Maxim
authors.initials: M
authors.lastname: Kireev
authors.forename: Alexander
authors.initials: A
authors.lastname: Korotkov
authors.forename: Natalia
authors.initials: N
authors.lastname: Medvedeva
authors.forename: Svyatoslav
authors.initials: S
authors.lastname: Medvedev
mesh_terms: D000328:Adult; D001921:Brain / Q000098:blood supply* / Q000000981:diagnostic imaging*; D001931:Brain Mapping; D008192:Deception; D005260:Female; D007839:Functional Laterality; D005717:Games, Experimental; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008014:Lie Detection; D008279:Magnetic Resonance Imaging; D008297:Male; D010100:Oxygen / Q000097:blood; D049268:Positron-Emission Tomography; D055815:Young Adult
chemical_list: D010100:Oxygen
keywords: Deception; Error detection; Functional magnetic resonance imaging; Positron emission tomography