title: Bioglycerol-based sulphonic acid functionalized carbon: an efficient and recyclable, solid acid catalyst for the regioselective azidolysis of epoxides in aqueous acetonitrile.
abstract: A convinent and efficient method was developed for the synthesis of 1,2-azidoalcohols by ring opening of terminal epoxides with sodium azide employing glycerol-based sulphonic acid functionalized carbon as heterogeneous catalyst in aqueous acetonitrile. The reaction is highly regioselective and affords the corresponding products in excellent yields (78-100%) under mild reaction conditions. The catalyst exhibited efficient reusability without loosing its activity even after 5 cycles of azidolysis of methyl 10,11-epoxy undecanoate under optimized conditions within 2 h.
authors.affiliation: Centre for Lipid Research, Indian Institute of Chemical Technology.
authors.forename: Manneganti
authors.initials: M
authors.lastname: Vijay
authors.forename: Rachapudi Badari Narayana
authors.initials: RB
authors.lastname: Prasad
authors.forename: Bethala Lakshmi Anu Prabhavathi
authors.initials: BL
authors.lastname: Devi
mesh_terms: D000097:Acetonitriles / Q000737:chemistry*; D000438:Alcohols / Q000138:chemical synthesis*; D001386:Azides / Q000138:chemical synthesis*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D004852:Epoxy Compounds / Q000737:chemistry*; D005990:Glycerol / Q000737:chemistry*; D019810:Sodium Azide / Q000737:chemistry*; D013451:Sulfonic Acids / Q000737:chemistry*; D013997:Time Factors; D014867:Water / Q000737:chemistry
chemical_list: D000097:Acetonitriles; D000438:Alcohols; D001386:Azides; D004852:Epoxy Compounds; D013451:Sulfonic Acids; D014867:Water; D002244:Carbon; D019810:Sodium Azide; D005990:Glycerol; C032159:acetonitrile