title: MicroRNA-148a: a potential therapeutic target for cancer.
abstract: MicroRNA-148a (miR-148a) which suppresses tumor growth by directly decreasing DNMT1 expression has been demonstrated as an important role for cancer therapy. The mechanisms for miR-148a in cancer will become potential future researches.
authors.affiliation: Institute for Liver Diseases of Anhui Medical University (AMU), School of Pharmacy, Anhui Key Laboratory of Bioactivity of Natural Products, Anhui Medical University, Hefei 230032, China.
authors.forename: Zhaolin
authors.initials: Z
authors.lastname: Chen
authors.forename: Taotao
authors.initials: T
authors.lastname: Ma
authors.forename: Cheng
authors.initials: C
authors.lastname: Huang
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Tao
authors.initials: T
authors.lastname: Xu
authors.forename: Tingting
authors.initials: T
authors.lastname: Hu
authors.forename: Jun
authors.initials: J
authors.lastname: Li
mesh_terms: D006801:Humans; D035683:MicroRNAs / Q000187:drug effects*; D009369:Neoplasms / Q000188:drug therapy* / Q000235:genetics
chemical_list: C550570:MIRN148 microRNA, human; D035683:MicroRNAs
keywords: CAFs; DNA methyltransferase 1; DNMT1; HCC; NFs; RUNX3; Runt-related transcription factor 3; cancer-associated fibroblasts; hepatocellular carcinoma; miR-148a; microRNA-148a; normal tissue fibroblasts