title: Treating symptomatic coronary artery disease in patients with Von Willebrand disease.
abstract: There is limited data on the occurrence of coronary artery disease (CAD) in patients with Von Willebrand disease and the literature is even scarce on their management. We at our institute reviewed the medical records of 198 patients with Von Willebrand disease over a period of 15years, of which 6 were found to have symptomatic CAD. Acute coronary syndrome was noted in 3 patients while the remaining 3 had stable angina. Cardiac catheterization showed that left main coronary artery was the culprit vessel in all of these patients. In terms of management, stents were placed in 3 patients, two of them underwent coronary artery bypass grafting, and the remaining one patient was medically managed. Aspirin, and in some patients clopidogrel, was well tolerated with minimal side effects.
authors.affiliation: Department of Internal Medicine, Henry Ford Hospital, Detroit, MI, USA. Electronic address: drhassan911@gmail.com.
authors.forename: Syed A
authors.initials: SA
authors.lastname: Hassan
authors.forename: Syed
authors.initials: S
authors.lastname: Amer
authors.forename: Waqas
authors.initials: W
authors.lastname: Qureshi
authors.forename: Zaid
authors.initials: Z
authors.lastname: Alirhayim
authors.forename: Philip
authors.initials: P
authors.lastname: Kuriakose
mesh_terms: D000368:Aged; D003324:Coronary Artery Disease / Q000209:etiology* / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014842:von Willebrand Diseases / Q000150:complications* / Q000628:therapy*
keywords: Acute coronary syndrome; Coronary artery disease; Von Willebrand disease