title: Selective Co/Ti cooperatively catalyzed biaryl couplings of aryl halides with aryl metal reagents.
abstract: Various aryl bromides or chlorides, including those bearing a free COOH, OH, CONHR, and SO2NHR group, coupled with aryl magnesium or lithium reagents in the presence of 7.5 mol % CoCl2/15 mol % PBu3 and substoichiometric Ti(OEt)4 (40 mol % to ArM) at room temperature in high yields with high chemo- and regioslectivity. This simple reaction represents the first example of Co/Ti cooperative catalysis which plays a key role in suppressing undesired homocouplings.
authors.affiliation: College of Chemistry, Beijing Normal University , Beijing, 100875, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zeng
authors.forename: Kun Ming
authors.initials: KM
authors.lastname: Liu
authors.forename: Xin Fang
authors.initials: XF
authors.lastname: Duan