title: SON sheds light on RNA splicing and pluripotency.
abstract: The role of RNA splicing in the regulation of stem cell properties has remained largely unexplored. The splicing-associated protein SON is now shown to be necessary for embryonic stem cell maintenance, by influencing the splicing of pluripotency regulators.
authors.affiliation: Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra (Givat Ram) Campus, Jerusalem, 91904, Israel.
authors.forename: Ilana
authors.initials: I
authors.lastname: Livyatan
authors.forename: Eran
authors.initials: E
authors.lastname: Meshorer
mesh_terms: D004268:DNA-Binding Proteins / Q000378:metabolism*; D053595:Embryonic Stem Cells / Q000378:metabolism; D006801:Humans; D015778:Minor Histocompatibility Antigens; D039904:Pluripotent Stem Cells / Q000378:metabolism*; D012326:RNA Splicing / Q000502:physiology*
chemical_list: D004268:DNA-Binding Proteins; D015778:Minor Histocompatibility Antigens; C088203:SON protein, human