title: Almanac 2013: acute coronary syndromes.
abstract: Unstable coronary artery plaque is the most common underlying cause of acute coronary syndromes (ACS) and can manifest as unstable angina, non-ST segment elevation infarction (NSTE-ACS), and ST elevation myocardial infarction (STEMI), but can also manifest as sudden cardiac arrest due to ischaemia induced tachyarrhythmias. ACS mortality has decreased signiﬁcantly over the last few years, especially from the more extreme manifestations of ACS, STEMI, and cardiac arrest. This trend is likely to continue based on recent therapeutic progress which includes novel antiplatelet agents such as prasugrel, ticagrelor, and cangrelor.
authors.affiliation: Yale-UCLH Cardiovascular Research Programme, The Heart Hospital, University College London Hospitals UCLH, UCLH16-18 Westmoreland Street, W1G 8PH, London-UK. pascalmeier74@gmail.com.
authors.forename: Pascal
authors.initials: P
authors.lastname: Meier
authors.forename: Alexandra J
authors.initials: AJ
authors.lastname: Lansky
authors.forename: Andreas
authors.initials: A
authors.lastname: Baumbach
mesh_terms: D054058:Acute Coronary Syndrome / Q000401:mortality / Q000628:therapy*; D006801:Humans; D009026:Mortality / Q000639:trends; D062645:Percutaneous Coronary Intervention / Q000706:statistics & numerical data; D014481:United States / Q000453:epidemiology