title: An image guided treatment platform for prostate cancer photodynamic therapy.
abstract: This study describes a multimodality images based platform to drive photodynamic therapies of prostate cancer using WST 11 TOOKAD Soluble drug. The platform integrates a pre-treatment planning tool based on magnetic resonance imaging and a per-treatment guidance tool based on transrectal ultrasound images. Evaluation of the platform on clinical data showed that prediction of the therapy outcome was possible with an accuracy of 90 %.
authors.forename: N
authors.initials: N
authors.lastname: Betrouni
authors.forename: P
authors.initials: P
authors.lastname: Colin
authors.forename: P
authors.initials: P
authors.lastname: Puech
authors.forename: A
authors.initials: A
authors.lastname: Villers
authors.forename: S
authors.initials: S
authors.lastname: Mordon
mesh_terms: D001429:Bacteriochlorophylls / Q000627:therapeutic use; D002138:Calibration; D004867:Equipment Design; D005682:Gadolinium / Q000737:chemistry; D006801:Humans; D007091:Image Processing, Computer-Assisted; D019018:Imagery, Psychotherapy; D021621:Imaging, Three-Dimensional / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D010778:Photochemotherapy / Q000295:instrumentation / Q000379:methods*; D011237:Predictive Value of Tests; D011467:Prostate / Q000473:pathology; D017430:Prostate-Specific Antigen; D011471:Prostatic Neoplasms / Q000188:drug therapy*; D015203:Reproducibility of Results; D016896:Treatment Outcome; D014463:Ultrasonography / Q000379:methods
chemical_list: D001429:Bacteriochlorophylls; C456120:palladium-bacteriopheophorbide; D005682:Gadolinium; D017430:Prostate-Specific Antigen