title: Evaluation of tumor blood flow after feeder embolization in meningiomas by arterial spin-labeling perfusion magnetic resonance imaging.
abstract: Preoperative embolization changes the amount of blood flow and pattern of flow distribution in meningioma. Tumor blood flow was investigated in eight meningioma patients before and after embolization using arterial spin-labeling (ASL) perfusion imaging. Although blood flow was significantly reduced in the whole tumor after embolization, changes in flow distribution patterns varied from one case to another. The findings suggest that evaluation of post-embolization tumor blood flow by ASL perfusion imaging would be useful in the surgical planning of meningioma.
authors.affiliation: Department of Neurosurgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kawaji
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Koizumi
authors.forename: Naoto
authors.initials: N
authors.lastname: Sakai
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Yamasaki
authors.forename: Hisaya
authors.initials: H
authors.lastname: Hiramatsu
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Kanoko
authors.forename: Mika
authors.initials: M
authors.lastname: Kamiya
authors.forename: Shuhei
authors.initials: S
authors.lastname: Yamashita
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Takehara
authors.forename: Harumi
authors.initials: H
authors.lastname: Sakahara
authors.forename: Hiroki
authors.initials: H
authors.lastname: Namba
mesh_terms: D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D002560:Cerebrovascular Circulation; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy*; D008579:Meningioma / Q000473:pathology / Q000628:therapy*; D008875:Middle Aged; D013113:Spin Labels; D016896:Treatment Outcome
chemical_list: D006490:Hemostatics; D013113:Spin Labels
keywords: ASL; Arterial spin-labeling; BBB; CT; DSC; ECA; Embolization; ICA; MMA; MRI; Meningioma; Perfusion imaging; ROI; T/N ratio; Tumor blood flow; arterial spin-labeling; blood–brain barrier; computed tomography; dynamic susceptibility contrast perfusion imaging; external carotid artery; internal carotid artery; magnetic resonance imaging; middle meningeal artery; region of interest; tumor/normal ratio