title: Enhanced peroxydisulfate electrochemiluminescence for dopamine biosensing based on Au nanoparticle decorated reduced graphene oxide.
abstract: This work reports a novel strategy to amplify the electrochemiluminescence (ECL) signal of peroxydisulfate solution based on the Au nanoparticle decorated reduced graphene oxide (Au NP-RGO), and further an ECL biosensor for sensitive and selective detection of dopamine (DA) was constructed. Due to the synergistic amplification of Au NPs and RGO, the ECL signal of peroxydisulfate solution on the Au NP-RGO modified electrode was about 5-fold enhanced compared to that of the bare electrode with the ECL onset potential positively shifted from -1.2 V to -0.9 V. More interestingly, the ECL intensity of peroxydisulfate solution increased with the increase of DA concentration, based on which an ECL biosensor for DA determination was fabricated. The as-prepared solid-state ECL DA sensor showed a wide linear response of 0.02-40 μM with a detection limit of 6.7 nM (S/N = 3). Moreover, we expect this work would open up a new field in the application of peroxydisulfate solution ECL for highly sensitive bioassays.
authors.affiliation: Key Laboratory of Modern Agriculture Equipment and Technology, School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, 212013, P.R. China. wangkun@ujs.edu.cn.
authors.forename: Yuting
authors.initials: Y
authors.lastname: Yan
authors.forename: Qian
authors.initials: Q
authors.lastname: Liu
authors.forename: Kun
authors.initials: K
authors.lastname: Wang
authors.forename: Ling
authors.initials: L
authors.lastname: Jiang
authors.forename: Xingwang
authors.initials: X
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: Qian
authors.forename: Xiaoya
authors.initials: X
authors.lastname: Dong
authors.forename: Baijing
authors.initials: B
authors.lastname: Qiu
mesh_terms: D015374:Biosensing Techniques; D004298:Dopamine / Q000032:analysis*; D055664:Electrochemical Techniques; D006046:Gold / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D049449:Luminescence; D053768:Metal Nanoparticles; D046529:Microscopy, Electron, Transmission; D010087:Oxides / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman; D013431:Sulfates / Q000737:chemistry*
chemical_list: D010087:Oxides; D013431:Sulfates; D006046:Gold; D006108:Graphite; D004298:Dopamine