title: [Super high-flux continuous hemodialysis in septic shock: a case report].
abstract: Continuous renal replacement therapy (CRRT) with a high cutoff (HCO) membrane is proposed for septic shock as a blood purification technique. The aim of this therapy is to modulate the immune response through the increase of the clearances of the inflammatory mediators as compared to standard CRRT. The use of HCO membranes in daily clinical practice is limited due to the related theoretical albumin loss. Super high-flux (SHF) membranes have an optimized cutoff and, when used in a diffusive mode, may allow for high clearances of middle molecules with limited albumin loss. We report the case of a patient with pneumonia and septic shock treated with continuous hemodialysis with a SHF membrane in order to present the clinical application of this new extracorporeal blood purification technique.
authors.affiliation: Service d'anesthésie-réanimation, pavillon P réanimation, hôpital Édouard-Herriot, 5, place d'Arsonval, 69437 Lyon cedex 03, France. Electronic address: thomas.madelaine@orange.fr.
authors.forename: Thomas
authors.initials: T
authors.lastname: Madelaine
authors.forename: Mathieu
authors.initials: M
authors.lastname: Page
authors.forename: Johanne
authors.initials: J
authors.lastname: Prothet
authors.forename: Charles-Éric
authors.initials: CÉ
authors.lastname: Ber
authors.forename: Julien
authors.initials: J
authors.lastname: Crozon
authors.forename: Bernard
authors.initials: B
authors.lastname: Allaouchiche
authors.forename: Thomas
authors.initials: T
authors.lastname: Rimmelé
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods; D012772:Shock, Septic / Q000628:therapy*
keywords: Blood purification; Choc septique; Cytokines; Hemodialysis; Hemofiltration; Hémodialyse; Hémofiltration; Purification sanguine; Septic shock