title: A cyanobenzo[a]phenoxazine-based near infrared lysosome-tracker for in cellulo imaging.
abstract: A cyanobenzo[a]phenoxazine-based pH probe with pKa = 5.0 exhibits OFF-ON emission at 625-850 nm upon excitation at 600 nm in aqueous buffers. The in cellulo imaging experiments with HeLa cells indicate that the probe can serve as a lysosome-specific probe under red light excitation (633 nm) with near infrared emission (650-790 nm).
authors.affiliation: College of Chemistry, Chemical Engineering and Material Science, Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, 199 Ren'Ai Road, Suzhou 215123, China. lujm@suda.edu.cn ge_jianfeng@hotmail.com.
authors.forename: Ru
authors.initials: R
authors.lastname: Sun
authors.forename: Wu
authors.initials: W
authors.lastname: Liu
authors.forename: Yu-Jie
authors.initials: YJ
authors.lastname: Xu
authors.forename: Jian-Mei
authors.initials: JM
authors.lastname: Lu
authors.forename: Jian-Feng
authors.initials: JF
authors.lastname: Ge
authors.forename: Masataka
authors.initials: M
authors.lastname: Ihara
mesh_terms: D005456:Fluorescent Dyes / Q000138:chemical synthesis; D006367:HeLa Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007259:Infrared Rays; D008027:Light; D008247:Lysosomes / Q000502:physiology*; D010078:Oxazines; D013050:Spectrometry, Fluorescence / Q000379:methods
chemical_list: D005456:Fluorescent Dyes; D010078:Oxazines; C039203:phenoxazine