title: Regioselective rapid synthesis of fully substituted 1,2,3-triazoles mediated by propargyl cations.
abstract: Regioselective rapid triazole syntheses at low temperature are described. Organic azides and propargyl cations generated by acids gave fully substituted 1H-1,2,3-triazoles. Most reactions could be performed in 5 min at not only rt but also -90 °C. Both terminal and internal alkynes were acceptable, and the sterically bulky substituents could afford the products smoothly. Various types of three-component coupling reactions were demonstrated, and the presence of allenylaminodiazonium intermediates was indicated.
authors.affiliation: Graduate School of Materials Science, Nara Institute of Science and Technology (NAIST) , 8916-5 Takayamacho, Ikoma, Nara 630-0192, Japan.
authors.forename: Huan
authors.initials: H
authors.lastname: Zhang
authors.forename: Hiroki
authors.initials: H
authors.lastname: Tanimoto
authors.forename: Tsumoru
authors.initials: T
authors.lastname: Morimoto
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Nishiyama
authors.forename: Kiyomi
authors.initials: K
authors.lastname: Kakiuchi