title: Peristaltic hemodynamics of a new pediatric circulatory assist system for Fontan circulation using shape memory alloy fibers.
abstract: Fontan procedure is one of the common surgical treatments of congenital heart diseases. Patients with Fontan circulation have single ventricle in the systemic circulation with the total cavopulmonary connection. We have been developing a pulmonary circulatory assist device using shape memory alloy fibers for Fontan circulation with total cavopulmonary connection. It consisted of the shape memory alloy fibers, the diameter of which are 100 µm. The fibers could wrap the ePTFE conduit for Fontan TCPC connection from the outside. We designed the sequential motion control system for sophisticated pulmonary hemodynamics by the pulsatile flow generation. In order to achieve pulsatile flow assistance in pulmonary arterial system, we fabricated a mechanical structure by sequential contraction of shape memory alloy fibers. Then, we developed a sequential contraction controller for the assist system, which could reproduce the wall contractile velocity at 6.0 to 20.0 cm/sec. We examined hemodynamic characteristic of its function using a mock circulatory system, which consisted of two overflow tanks representing venous and pulmonary arterial pressures in Fontan circulation. As a result, the pulmonary circulation assist device with sequential contraction could achieve effective promotion of the pulsatility in pulmonary arterial flow.
authors.forename: A
authors.initials: A
authors.lastname: Yamada
authors.forename: Y
authors.initials: Y
authors.lastname: Shiraishi
authors.forename: H
authors.initials: H
authors.lastname: Miura
authors.forename: T
authors.initials: T
authors.lastname: Yambe
authors.forename: M H
authors.initials: MH
authors.lastname: Omran
authors.forename: T
authors.initials: T
authors.lastname: Shiga
authors.forename: Y
authors.initials: Y
authors.lastname: Tsuboko
authors.forename: D
authors.initials: D
authors.lastname: Homma
authors.forename: M
authors.initials: M
authors.lastname: Yamagishi
mesh_terms: D006348:Cardiac Surgical Procedures / Q000295:instrumentation; D002648:Child; D018729:Fontan Procedure / Q000295:instrumentation*; D006330:Heart Defects, Congenital / Q000503:physiopathology / Q000601:surgery*; D006352:Heart Ventricles / Q000601:surgery; D006439:Hemodynamics; D006801:Humans; D015918:Infusion Pumps, Implantable; D009200:Myocardial Contraction; D011651:Pulmonary Artery / Q000503:physiopathology / Q000601:surgery; D011652:Pulmonary Circulation; D011673:Pulsatile Flow