title: Cerebral protection against left ventricular thrombus during transcatheter aortic valve replacement in a patient with critical aortic stenosis.
abstract: Transcatheter aortic valve replacement is an increasingly common treatment of critical aortic stenosis. Many aortic stenosis patients have concomitant left ventricular dysfunction, which can instigate the formation of thrombus resistant to anticoagulation. Recent trials evaluating transcatheter aortic valve replacement have excluded patients with left ventricular thrombus. We present a case in which an 86-year-old man with known left ventricular thrombus underwent successful transcatheter aortic valve replacement under cerebral protection.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, University of Miami Miller School of Medicine, Miami, Florida 33136.
authors.forename: Peeyush M
authors.initials: PM
authors.lastname: Grover
authors.forename: Brian P
authors.initials: BP
authors.lastname: O'Neill
authors.forename: Omaida
authors.initials: O
authors.lastname: Velazquez
authors.forename: Alan W
authors.initials: AW
authors.lastname: Heldman
authors.forename: William W
authors.initials: WW
authors.lastname: O'Neill
authors.forename: Mauricio G
authors.initials: MG
authors.lastname: Cohen
mesh_terms: D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D001281:Atrial Fibrillation / Q000150:complications* / Q000175:diagnosis; D006328:Cardiac Catheterization / Q000295:instrumentation*; D016638:Critical Illness; D057505:Embolic Protection Devices; D006331:Heart Diseases / Q000175:diagnosis / Q000209:etiology*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006352:Heart Ventricles; D006801:Humans; D020766:Intracranial Embolism / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D008297:Male; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology*; D016896:Treatment Outcome
keywords: Aortic valve stenosis/therapy; cerebral infarction/etiology; embolic protection devices; heart valve prosthesis implantation; intracranial embolism/prevention & control; stroke/etiology; thrombus, left ventricular