title: The role of epidemiology in the era of molecular epidemiology and genomics: Summary of the 2013 AJE-sponsored Society of Epidemiologic Research Symposium.
abstract: On June 20, 2013, the American Journal of Epidemiology sponsored a symposium at the Society for Epidemiologic Research's 46th Annual Meeting in Boston, Massachusetts, entitled, "What Is the Role of Epidemiology in the Era of Molecular Biology and Genomics?" The future of epidemiology depends on innovation in generating interesting and important testable hypotheses that are relevant to population health. These new strategies will depend on new technology, both in measurement of agents and environment and in the fields of pathophysiology and outcomes, such as cellular epidemiology and molecular pathology. The populations to be studied, sample sizes, and study designs should be selected based on the hypotheses to be tested and include case-control, cohort, and clinical trials. Developing large mega cohorts without attention to specific hypotheses is inefficient, will fail to address many associations with high-quality data, and may well produce spurious results.
authors.forename: Lewis H
authors.initials: LH
authors.lastname: Kuller
authors.forename: Michael B
authors.initials: MB
authors.lastname: Bracken
authors.forename: Shuji
authors.initials: S
authors.lastname: Ogino
authors.forename: Ross L
authors.initials: RL
authors.lastname: Prentice
authors.forename: Russell P
authors.initials: RP
authors.lastname: Tracy
mesh_terms: D000486:Allergy and Immunology; D004777:Environment; D004812:Epidemiologic Methods; D016021:Epidemiologic Studies; D004813:Epidemiology / Q000458:organization & administration*; D023281:Genomics / Q000458:organization & administration*; D015438:Health Behavior; D006801:Humans; D007256:Information Systems; D008019:Life Style; D008967:Molecular Biology / Q000458:organization & administration*; D010641:Phenotype
keywords: immunology; pathology; study design