title: Chick stem cells: current progress and future prospects.
abstract: Chick embryonic stem cells (cESCs) can be derived from cells obtained from stage X embryos (blastoderm stage); these have the ability to contribute to all somatic lineages in chimaeras, but not to the germ line. However, lines of stem cells that are able to contribute to the germ line can be established from chick primordial germ cells (cPGCs) and embryonic germ cells (cEGCs). This review provides information on avian stem cells, emphasizing different sources of cells and current methods for derivation and culture of pluripotent cells from chick embryos. We also review technologies for isolation and derivation of chicken germ cells and the production of transgenic birds.
authors.affiliation: Department of Cell and Developmental Biology and UCL Centre for Stem Cells and Regenerative Medicine, University College London, Gower Street, London WC1E 6BT, UK.
authors.forename: Sittipon
authors.initials: S
authors.lastname: Intarapat
authors.forename: Claudio D
authors.initials: CD
authors.lastname: Stern
mesh_terms: D000650:Amnion / Q000166:cytology; D000818:Animals; D030801:Animals, Genetically Modified; D002469:Cell Separation; D002645:Chickens; D053595:Embryonic Stem Cells / Q000166:cytology* / Q000378:metabolism; D005854:Germ Cells / Q000166:cytology / Q000378:metabolism; D057026:Induced Pluripotent Stem Cells / Q000166:cytology / Q000378:metabolism; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000378:metabolism; D018482:Muscle, Skeletal / Q000166:cytology; D058953:Neural Stem Cells / Q000166:cytology / Q000378:metabolism