title: Local recurrence as a first sign of parathyroid malignancy! Need to redefine the criteria for diagnosis of parathyroid carcinoma.
abstract: Pathological criteria alone do not make an accurate diagnosis of parathyroid carcinoma in cases of well-defined organ contained lesion without local and distant metastasis. Intra-operative appearance of pale, grayish, firm tumor is highly suggestive of parathyroid carcinoma, even though this finding is not included in the pathological criteria for diagnosing a malignancy. Gross features of the tumor also should be added to the pathological criteria so as to ensure an accurate assessment of the biological behavior of the parathyroid tumor.
authors.affiliation: Department of Endocrine Surgery, Narayana Medical College and Superspeciality Hospital, Chinthareddypalem, Nellore, Andhra Pradesh, India.
authors.forename: P V
authors.initials: PV
authors.lastname: Pradeep
authors.forename: Vydehi Venkata
authors.initials: VV
authors.lastname: Bheemaraju
keywords: Adenoma; parathyroid carcinoma; primary hyperparathyroidism