title: Why Candida sepsis should matter to ICU physicians.
abstract: The incidence of candidemia and invasive Candida infections has increased substantially over the last 2 decades. These infections are associated with risk factors that characterize intensive care unit patients. Candidemia and invasive Candida are highly morbid and associated with significantly increased mortality. Outcomes in the intensive care setting depend on physician awareness and rapid intervention. The epidemiology of the disease, its diagnostic challenges, and management strategies, including prophylactic, preemptive, and definitive therapeutic approaches, are presented herein.
authors.affiliation: Department of Medicine, Université de Montréal, 5415 Boulevard De l'Assomption, Montréal, Québec H1T 2M4, Canada; Respiratory Critical Care Group, Respiratory Health Network of the FRQS, Montréal, Québec, Canada. Electronic address: yoanna.skrobik@umontreal.ca.
authors.forename: Yoanna
authors.initials: Y
authors.lastname: Skrobik
authors.forename: Michel
authors.initials: M
authors.lastname: Laverdiere
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002175:Candida; D058387:Candidemia / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D004347:Drug Interactions; D005283:Fentanyl / Q000494:pharmacology; D006801:Humans; D017053:Infection Control / Q000379:methods*; D007362:Intensive Care Units / Q000458:organization & administration*; D008874:Midazolam / Q000494:pharmacology; D012307:Risk Factors
chemical_list: D000935:Antifungal Agents; D008874:Midazolam; D005283:Fentanyl
keywords: Candidemia; Critical care; Intensive care; Invasive candidiasis; Sepsis