title: Are sexes affected differently by ketamine? An exploratory study in ketamine users.
abstract: One hundred primary ketamine users and 100 controls were recruited in Hong Kong between December 2009 and December 2011. Cognitive assessment included general intelligence, working, verbal, and visual memory, and executive functions. A Univariate General Linear Model was used to compare cognitive performance between the male and female ketamine users and controls. The female users appeared to have a higher risk of visual memory impairment than their male counterparts. Further studies are warranted to clarify the mechanism of the sex-specific effect of ketamine on cognitive functions.
authors.affiliation: 1Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Hua Jun
authors.initials: HJ
authors.lastname: Liang
authors.forename: Chieh Grace
authors.initials: CG
authors.lastname: Lau
authors.forename: Ka Lam Alan
authors.initials: KL
authors.lastname: Tang
authors.forename: Fu
authors.initials: F
authors.lastname: Chan
authors.forename: Gabor Sandor
authors.initials: GS
authors.lastname: Ungvari
authors.forename: Wai Kwong
authors.initials: WK
authors.lastname: Tang
mesh_terms: D016022:Case-Control Studies; D003071:Cognition / Q000187:drug effects*; D005260:Female; D006801:Humans; D007649:Ketamine / Q000494:pharmacology*; D016014:Linear Models; D008297:Male; D008568:Memory / Q000187:drug effects*; D012737:Sex Factors; D019966:Substance-Related Disorders / Q000150:complications*
chemical_list: D007649:Ketamine