title: The effects of restorative composite resins on the cytotoxicity of dentine bonding agents.
abstract: During restoration of damaged teeth in dental clinics, dentin bonding agents are usually overlaid with restorative resin composites. The purpose of this study was to investigate the effects of restorative resin composites on cytotoxicity of dentin bonding agents. Dentin bonding agents were placed on glass discs, pre-cured and uncured resin composite discs. Bonding agents on the glass discs and composite resins discs were light cured and used for agar overlay cytotoxicity testing. Dentin bonding agents on composite resin discs exhibited far less cytotoxicity than that on glass discs. The polymerization of resin composite increased the surface hardness and decreased the cytotoxicity of bonding agents. In conclusion, composite resins in dental restorations are expected to enhance the polymerization of dentin bonding agents and reduce the elution of resin monomers, resulting in the decrease of cytotoxicity.
authors.affiliation: Department of Dental Biomaterials Science and Dental Research Institute, School of Dentistry, Seoul National University.
authors.forename: Kyunghwan
authors.initials: K
authors.lastname: Kim
authors.forename: Kyung Mi
authors.initials: KM
authors.lastname: Son
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Kwon
authors.forename: Bum-Soon
authors.initials: BS
authors.lastname: Lim
authors.forename: Hyeong-Cheol
authors.initials: HC
authors.lastname: Yang
mesh_terms: D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects*; D003793:Dental Restoration, Permanent / Q000379:methods*; D017220:Dentin-Bonding Agents / Q000633:toxicity*; D005347:Fibroblasts / Q000187:drug effects; D051379:Mice; D008855:Microscopy, Electron, Scanning; D012117:Resins, Synthetic
chemical_list: D017220:Dentin-Bonding Agents; D012117:Resins, Synthetic