title: Mobile genetic elements of Pseudomonas aeruginosa isolates from hydrotherapy facility and respiratory infections.
abstract: The content of mobile genetic elements in Pseudomonas aeruginosa isolates of a pristine natural mineral water system associated with healthcare was compared with clinical isolates from respiratory infections. One isolate, from the therapy pool circuit, presented a class 1 integron, with 100% similarity to a class 1 integron contained in plasmid p4800 of the Klebsiella pneumoniae Kp4800 strain, which is the first time it has been reported in P. aeruginosa. Class 1 integrons were found in 25.6% of the clinical isolates. PAGI1 orf3 was more prevalent in environmental isolates, while PAGI2 c105 and PAGI3 sg100 were more prevalent in clinical isolates. Plasmids were not observed in either population.
authors.affiliation: Center for Pharmaceutical Studies, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.
authors.forename: S G
authors.initials: SG
authors.lastname: Pereira
authors.forename: O
authors.initials: O
authors.lastname: Cardoso
mesh_terms: D003428:Cross Infection / Q000382:microbiology*; D004251:DNA Transposable Elements; D004269:DNA, Bacterial; D016680:Genome, Bacterial; D006757:Hospital Units; D006801:Humans; D006875:Hydrotherapy / Q000009:adverse effects; D011552:Pseudomonas Infections / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D012141:Respiratory Tract Infections / Q000382:microbiology*
chemical_list: D004251:DNA Transposable Elements; D004269:DNA, Bacterial
keywords: Genomic islands; Pseudomonas aeruginosa; horizontal gene transfer; integrons; mobile genetic elements