title: Vogt Koyanagi Harada disease: treatment and visual prognosis.
abstract: Vogt Koyanagi Harada (VKH) disease is a chronic, bilateral, granulomatous panuveitis associated with central nervous system, auditory and integumentary manifestations. The study was conducted from January 2001 to December 2010 at the Department of Ophthalmology, Khyber Teaching Hospital, Peshawar. A total of 9 patients with diagnosis of Vogt Koyanagi Harada disease were included in the study. Extracted data included age, gender, duration of disease, initial and final visual acuities, treatment and complications. Initial visual acuity was ranging from 6/24 to perception of light. All the patients were treated with systemic and topical corticosteroids. In addition, one patient also received cytotoxic therapy. Final visual acuity was 6/18 or better in all cases (100%). One patient developed bilateral cataract, glaucoma and subretinal fibrosis at the macula. The cataract and glaucoma were managed as per established protocols. The visual prognosis of Vogt Koyanagi Harada disease is generally favourable if the disease is identified early and adequately treated and the associated complications are addressed properly.
authors.affiliation: Department of Ophthalmology, Eye 'B' Unit, Khyber Teaching Hospital, Peshawar.
authors.forename: Mumtaz
authors.initials: M
authors.lastname: Alam
authors.forename: Mustafa
authors.initials: M
authors.lastname: Iqbal
authors.forename: Bakht Samar
authors.initials: BS
authors.lastname: Khan
authors.forename: Ibrar
authors.initials: I
authors.lastname: Hussain
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011379:Prognosis; D016896:Treatment Outcome; D014607:Uveomeningoencephalitic Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D014785:Vision, Ocular; D014792:Visual Acuity / Q000502:physiology*; D055815:Young Adult
chemical_list: D005938:Glucocorticoids