title: Biocompatible bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films.
abstract: A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as cross-linker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications.
authors.affiliation: Department of Chemistry and CICECO, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.
authors.forename: Andrea G P R
authors.initials: AG
authors.lastname: Figueiredo
authors.forename: Ana R P
authors.initials: AR
authors.lastname: Figueiredo
authors.forename: Ana
authors.initials: A
authors.lastname: Alonso-Varona
authors.forename: Susana C M
authors.initials: SC
authors.lastname: Fernandes
authors.forename: Teodoro
authors.initials: T
authors.lastname: Palomares
authors.forename: Eva
authors.initials: E
authors.lastname: Rubio-Azpeitia
authors.forename: Ana
authors.initials: A
authors.lastname: Barros-Timmons
authors.forename: Armando J D
authors.initials: AJ
authors.lastname: Silvestre
authors.forename: Carlos
authors.initials: C
authors.lastname: Pascoal Neto
authors.forename: Carmen S R
authors.initials: CS
authors.lastname: Freire
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry* / Q000627:therapeutic use; D002482:Cellulose / Q000737:chemistry* / Q000627:therapeutic use; D041821:Gluconacetobacter / Q000737:chemistry*; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000187:drug effects; D008689:Methacrylates / Q000737:chemistry; D053761:Nanocomposites / Q000008:administration & dosage / Q000737:chemistry* / Q000627:therapeutic use; D011092:Polyethylene Glycols / Q000737:chemistry; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; D008689:Methacrylates; C437167:poly(ethylene glycol)diacrylate; D011092:Polyethylene Glycols; C005044:hydroxyethyl methacrylate; D002482:Cellulose