title: Dental pulp response to collagen and pulpotec cement as pulpotomy agents in primary dentition: A histological study.
abstract: BACKGROUND
  As the search for a better biocompatible medicament is on, aim of the present study was to evaluate the pulpal response to collagen particles impregnated in antibiotics (Biofil-AB™) and new commercially available cement (Pulpotec) that can be used as pulpal medicament.
  
  
  METHODS
  Total sample of 40 teeth from 20 children in the age group of 7-10 years which are noncarious having bilateral retained primary teeth were enrolled for the study. Nine teeth each were treated with collagen particles (group I) and Pulpotec cement (group II), and the remaining samples were discarded due to various reasons. Both groups were randomly subdivided into three teeth each that were extracted after 7, 15, and 30 days intervals and examined histologically.
  
  
  RESULTS
  Moderate to severe inflammatory cells with newly formed blood vessels and disorganized odontoblastic cell layer was observed in group I after all three intervals with dentinal bridge formation in two specimens. On contrary, none of the specimens in group II showed any signs of inflammation, but there was a discontinuity in the odontoblastic layer lining along the dentin walls.
  
  
  CONCLUSIONS
  Both materials were proven to be promising alternatives as pulp medicaments. However, collagen was found to be a better material.
authors.affiliation: Department of Pedodontics, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India.
authors.forename: Pranitha
authors.initials: P
authors.lastname: Kakarla
authors.forename: Jogendra Sai Sankar
authors.initials: JS
authors.lastname: Avula
authors.forename: George Manojkumar
authors.initials: GM
authors.lastname: Mellela
authors.forename: Sujatha
authors.initials: S
authors.lastname: Bandi
authors.forename: Sampath
authors.initials: S
authors.lastname: Anche
keywords: Collagen; Pulpotec® cement; pulpotomy