title: GLM analysis of time resolved NIRS data of motor activation during different motor tasks.
abstract: The hemodynamic response to motor activation was investigated by time-resolved NIRS in healthy subjects and patients with unilateral impairment in motor ability. Healthy subjects performed a simple and a complex finger movement task, patients a handgrip task. A General Linear Model approach (GLM) was applied during NIRS data processing. In general, compared to the integral (continuous wave signal), higher significance of activation was found for the variance signal that selectively represents changes in the deep compartment. A discussion of GLM results with respect to task complexity and difficulty is provided.
authors.forename: Erika
authors.initials: E
authors.lastname: Molteni
authors.forename: Heidrun
authors.initials: H
authors.lastname: Wabnitz
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Bianchi
authors.forename: Oliver
authors.initials: O
authors.lastname: Steinkellner
authors.forename: Tilmann
authors.initials: T
authors.lastname: Sander-Thoemmes
authors.forename: Frederik
authors.initials: F
authors.lastname: Geisler
authors.forename: Bruno-Marcel
authors.initials: BM
authors.lastname: Mackert
authors.forename: Stefanie
authors.initials: S
authors.lastname: Leistner
authors.forename: Sergio
authors.initials: S
authors.lastname: Cerutti
mesh_terms: D000328:Adult; D020520:Brain Infarction / Q000097:blood* / Q000503:physiopathology; D016022:Case-Control Studies; D005260:Female; D018737:Hand Strength; D006439:Hemodynamics; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D019265:Spectroscopy, Near-Infrared
chemical_list: D006454:Hemoglobins