title: [Antidepressant treatment associated hyponatremia -- case report].
abstract: Hyponatremia is a potential side-effect of antidepressants that was observed most frequently in connection with compounds acting on the serotonin system. Risk of hyponatremia was found to be higher in the elderly. Authors report a case of a 65-year old male patient who was treated with venlafaxine-mirtazapine combination for recurrent depression. Severe hyponatremia, requiring intensive care, emerged in connection with the treatment. The authors emphasize the importance of the regular checking of serum sodium levels during antidepressant treatment, especially in elderly patients.
authors.affiliation: Egyesített Szent István és Szent László Kórház-Rendelőintézet, Szent László Kórház, IV. Belgyógyászati osztály, Budapest, Hungary. gazdag@lamb.hu.
authors.forename: Zsófia
authors.initials: Z
authors.lastname: Bognár
authors.forename: Gabriella
authors.initials: G
authors.lastname: Vonyik
authors.forename: Gábor
authors.initials: G
authors.lastname: Gazdag
mesh_terms: D000368:Aged; D018687:Antidepressive Agents, Second-Generation / Q000008:administration & dosage; D000929:Antidepressive Agents, Tricyclic / Q000008:administration & dosage / Q000009:adverse effects*; D003422:Critical Care; D003511:Cyclohexanols / Q000008:administration & dosage; D003863:Depression / Q000188:drug therapy; D003865:Major Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D006801:Humans; D007010:Hyponatremia / Q000097:blood / Q000139:chemically induced* / Q000628:therapy; D008297:Male; D008803:Mianserin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D000078785:Mirtazapine; D012008:Recurrence; D012720:Severity of Illness Index; D012964:Sodium / Q000097:blood*; D013406:Suicide, Attempted / Q000517:prevention & control; D016896:Treatment Outcome; D000069470:Venlafaxine Hydrochloride
chemical_list: D018687:Antidepressive Agents, Second-Generation; D000929:Antidepressive Agents, Tricyclic; D003511:Cyclohexanols; D008803:Mianserin; D000069470:Venlafaxine Hydrochloride; D012964:Sodium; D000078785:Mirtazapine