title: Radiation dose reduction in paranasal sinus CT using model-based iterative reconstruction.
abstract: OBJECTIVE
  CT performed with Veo model-based iterative reconstruction has shown the potential for radiation-dose reduction. This study sought to determine whether Veo could reduce noise and improve the image quality of low-dose sinus CT.
  
  
  METHODS
  Twenty patients consented to participate and underwent low- and standard-dose sinus CT on the same day. Standard-dose CT was created with filtered back-projection (120 kV[peak], 210 mA, 0.4-second rotation, and 0.531 pitch). For low-dose CT, mA was decreased to 20 (the remaining parameters were unchanged), and images were generated with filtered back-projection and Veo. Standard- and low-dose datasets were reconstructed by using bone and soft-tissue algorithms, while the low-dose Veo reconstruction only had a standard kernel. Two blinded neuroradiologists independently evaluated the image quality of multiple osseous and soft-tissue craniofacial structures. Image noise was measured by using multiple regions of interest.
  
  
  RESULTS
  Eight women and 12 men (mean age, 63.3 years) participated. Volume CT dose indices were 2.9 mGy (low dose) and 31.6 mGy (standard dose), and mean dose-length products were 37.4 mGy-cm (low dose) and 406.1 mGy-cm (standard dose). Of all the imaging series, low-dose Veo demonstrated the least noise (P < .001). Compared with filtered back-projection low-dose CT using soft-tissue and bone algorithms, Veo had the best soft-tissue image quality but the poorest bone image quality (P < .001).
  
  
  CONCLUSIONS
  Veo significantly reduces noise in low-dose sinus CT. Although this reduction improves soft-tissue evaluation, thin bone becomes less distinct.
authors.affiliation: From the Departments of Radiology (J.M.H., G.P.F., A.C.P., R.G.P, A.K.H.).
authors.forename: J M
authors.initials: JM
authors.lastname: Hoxworth
authors.forename: D
authors.initials: D
authors.lastname: Lal
authors.forename: G P
authors.initials: GP
authors.lastname: Fletcher
authors.forename: A C
authors.initials: AC
authors.lastname: Patel
authors.forename: M
authors.initials: M
authors.lastname: He
authors.forename: R G
authors.initials: RG
authors.lastname: Paden
authors.forename: A K
authors.initials: AK
authors.lastname: Hara
mesh_terms: D000368:Aged; D000465:Algorithms; D016477:Artifacts; D001921:Brain / Q000000981:diagnostic imaging; D015331:Cohort Studies; D005123:Eye / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography / Q000379:methods* / Q000592:standards; D010254:Paranasal Sinus Diseases / Q000000981:diagnostic imaging*; D011300:Preoperative Care / Q000379:methods / Q000592:standards; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement / Q000379:methods / Q000592:standards