title: Bordetella holmesii bacteremia cases in the United States, April 2010-January 2011.
abstract: We describe the first report of temporally related cases of Bordetella holmesii bacteremia. Demographic and clinical data were collected through chart abstraction and case-patient interviews. Twenty-two cases were identified from 6 states. Symptom onset dates ranged from April 2010 to January 2011. Median age of patients was 17.1 years and 64% had functional or anatomic asplenia. Pulsed-field gel electrophoresis profiles of a sample of isolates were identical. These cases occurred during a peak in pertussis outbreaks with documented cases of B. holmesii/Bordetella pertussis respiratory coinfection; whether there is a link between B. holmesii respiratory and bloodstream infection is unknown.
authors.affiliation: Meningitis and Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: Sara Y
authors.initials: SY
authors.lastname: Tartof
authors.forename: Prabhu
authors.initials: P
authors.lastname: Gounder
authors.forename: Don
authors.initials: D
authors.lastname: Weiss
authors.forename: Lillian
authors.initials: L
authors.lastname: Lee
authors.forename: Pamela K
authors.initials: PK
authors.lastname: Cassiday
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Clark
authors.forename: Elizabeth C
authors.initials: EC
authors.lastname: Briere
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology; D001884:Bordetella / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D001885:Bordetella Infections / Q000453:epidemiology* / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D004269:DNA, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D058889:Molecular Typing; D013154:Spleen / Q000002:abnormalities; D014481:United States / Q000453:epidemiology; D014917:Whooping Cough / Q000150:complications / Q000453:epidemiology; D055815:Young Adult
chemical_list: D004269:DNA, Bacterial
keywords: Bordetella holmesii; asplenia; bacteremia; pertussis