title: [Management of cognitive impairment in children and adolescents with cerebral palsy treated with pantocalcin].
abstract: A randomized study on the efficacy and safety of the hopantenic acid preparation (pantocalcin) and its effect on cognitive functions in children with cerebral palsy (CCP) has been carried out. The positive effect of pantocalcin on the visual memory and attention concentration, activity and fatigability has been shown. At the same time, there was a decrease of anxiety in children and adolescents with CCP. No evidence for the effect of the drug on visual-motor skills has been found. The results of the study have demonstrated the high safety profile of pantocalcin when used in pediatric practice.
authors.affiliation: Nauchno-prakticheskiĭ tsentr detskoĭ psikhonevrologii Departamenta zdravookhraneniia Moskvy.
authors.forename: T T
authors.initials: TT
authors.lastname: Batysheva
authors.forename: A N
authors.initials: AN
authors.lastname: Platonova
authors.forename: N V
authors.initials: NV
authors.lastname: Chebanenko
authors.forename: O V
authors.initials: OV
authors.lastname: Bykova
mesh_terms: D000293:Adolescent; D001007:Anxiety / Q000209:etiology; D001288:Attention / Q000187:drug effects; D002547:Cerebral Palsy / Q000188:drug therapy*; D002648:Child; D003071:Cognition / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects; D009048:Motor Skills / Q000187:drug effects; D018697:Nootropic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D010205:Pantothenic Acid / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005680:gamma-Aminobutyric Acid / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D018697:Nootropic Agents; C016030:pantogab; D010205:Pantothenic Acid; D005680:gamma-Aminobutyric Acid