title: Pathology in metopic synostosis.
abstract: Premature closure and subsequent ossification of the metopic suture results in triangular head shape called trigonocephaly and is characterized by a midline metopic ridge, frontotemporal narrowing, and an increased biparietal diameter. Trigonocephaly is the second most frequent type of craniosynostosis. It can be isolated and associated with other congenital anomalies without any known syndrome, or occurs as part of a multiple malformation syndrome. Improvement in treatment is directed by a thorough understanding of the basic pathology of this condition. This review aims to provide an overview of metopic synostosis by correlating what is known about pathogenesis and pathology of this entity.
authors.affiliation: Department of Pathology, Faculty of Medicine, Selcuk University, Candir mah. Candir sok. Hazal sitesi No. 24/C, 42090, Meram, Konya, Turkey, pinarkarabagli@yahoo.com.
authors.forename: Pinar
authors.initials: P
authors.lastname: Karabagli
mesh_terms: D003393:Cranial Sutures / Q000473:pathology; D003398:Craniosynostoses / Q000473:pathology*; D006801:Humans