title: U2AF1 mutations in primary myelofibrosis are strongly associated with anemia and thrombocytopenia despite clustering with JAK2V617F and normal karyotype.
authors.affiliation: Division of Hematology, Mayo Clinic, Department of Medicine, Rochester, MN, USA.
authors.forename: A
authors.initials: A
authors.lastname: Tefferi
authors.affiliation: Division of Hematology, Mayo Clinic, Department of Medicine, Rochester, MN, USA.
authors.forename: C M
authors.initials: CM
authors.lastname: Finke
authors.affiliation: Division of Hematology, Mayo Clinic, Department of Medicine, Rochester, MN, USA.
authors.forename: T L
authors.initials: TL
authors.lastname: Lasho
authors.affiliation: Division of Hematology, Mayo Clinic, Department of Medicine, Rochester, MN, USA.
authors.forename: E A
authors.initials: EA
authors.lastname: Wassie
authors.affiliation: Division of Cytogenetics, Mayo Clinic, Rochester, MN, USA.
authors.forename: R
authors.initials: R
authors.lastname: Knudson
authors.affiliation: Division of Cytogenetics, Mayo Clinic, Rochester, MN, USA.
authors.forename: R P
authors.initials: RP
authors.lastname: Ketterling
authors.affiliation: Division of Hematopathology, Mayo Clinic, Rochester, MN, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Hanson
authors.affiliation: Division of Hematology, Mayo Clinic, Department of Medicine, Rochester, MN, USA.
authors.forename: A
authors.initials: A
authors.lastname: Pardanani
mesh_terms: D000740:Anemia / Q000209:etiology*; D006801:Humans; D053614:Janus Kinase 2 / Q000235:genetics*; D059785:Karyotype; D009154:Mutation; D009687:Nuclear Proteins / Q000235:genetics*; D055728:Primary Myelofibrosis / Q000150:complications* / Q000235:genetics*; D012261:Ribonucleoproteins / Q000235:genetics*; D000072668:Splicing Factor U2AF; D013921:Thrombocytopenia / Q000209:etiology*
chemical_list: D009687:Nuclear Proteins; D012261:Ribonucleoproteins; D000072668:Splicing Factor U2AF; C076753:U2AF1 protein, human; D053614:Janus Kinase 2