title: Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase.
authors.affiliation: Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.
authors.forename: Shannon
authors.initials: S
authors.lastname: Nangle
authors.forename: Weiman
authors.initials: W
authors.lastname: Xing
authors.forename: Ning
authors.initials: N
authors.lastname: Zheng
mesh_terms: D000818:Animals; D001665:Binding Sites; D002227:Carbazoles / Q000737:chemistry / Q000378:metabolism; D056931:Cryptochromes / Q000737:chemistry* / Q000378:metabolism; D018360:Crystallography, X-Ray; D044783:F-Box Proteins / Q000737:chemistry / Q000378:metabolism; D005182:Flavin-Adenine Dinucleotide / Q000737:chemistry / Q000378:metabolism; D051379:Mice; D008958:Models, Molecular; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D013449:Sulfonamides / Q000737:chemistry / Q000378:metabolism; D044767:Ubiquitin-Protein Ligases / Q000737:chemistry* / Q000378:metabolism
chemical_list: D002227:Carbazoles; C538967:Cry2 protein, mouse; D056931:Cryptochromes; D044783:F-Box Proteins; C519794:Fbxl3 protein, mouse; C574808:KL001; D013449:Sulfonamides; D005182:Flavin-Adenine Dinucleotide; D044767:Ubiquitin-Protein Ligases