title: Biomarkers of acute kidney injury.
abstract: Creatinine remains the standard for laboratory diagnosis of AKI. Efforts to prevent nephrotoxicity have been harmed by the delay in the diagnosis of AKI criteria by using only the creatinine as a marker, therefore there is great interest in identifying early reliable biomarkers. Moreover, early treatment of ARF can be correlated with a better prognosis and identification of biomarkers for early diagnosis would improve the efficacy of a therapeutic strategy. Thus, it becomes imperative to find biomarkers that can stratify correctly the extent of renal damage that each patient has suffered and the risk of developing chronic kidney disease (CKD). Here, we review the main features of emerging biomarkers in nephrology.
authors.forename: Luis Alberto Batista
authors.initials: LA
authors.lastname: Peres
authors.forename: Ademar Dantas da
authors.initials: AD
authors.lastname: Cunha Júnior
authors.forename: Alex Júnior
authors.initials: AJ
authors.lastname: Schäfer
authors.forename: Aline Liene da
authors.initials: AL
authors.lastname: Silva
authors.forename: Arianne Ditzel
authors.initials: AD
authors.lastname: Gaspar
authors.forename: Deborah Francisca
authors.initials: DF
authors.lastname: Scarpari
authors.forename: Julia Barazetti Ferrari
authors.initials: JB
authors.lastname: Alves
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Girelli Neto
authors.forename: Thaís Figueiredo Teodoro de
authors.initials: TF
authors.lastname: Oliveira
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood* / Q000175:diagnosis*; D000209:Acute-Phase Proteins; D015415:Biomarkers / Q000097:blood; D003404:Creatinine / Q000097:blood; D006801:Humans; D000071068:Lipocalin-2; D054834:Lipocalins / Q000097:blood; D011518:Proto-Oncogene Proteins / Q000097:blood
chemical_list: D000209:Acute-Phase Proteins; D015415:Biomarkers; C489506:LCN2 protein, human; D000071068:Lipocalin-2; D054834:Lipocalins; D011518:Proto-Oncogene Proteins; D003404:Creatinine