title: Preclosure of femoral vein access site with the suture-mediated Proglide device during MitraClip implantation.
abstract: This study was designed to show the feasibility, safety, and efficacy of venous access-site closure with a single 6 Fr suture-mediated Proglide (Abbott Vascular) during MitraClip procedures.
  
  
  METHODS
  Preclosure of the right femoral vein with Proglide used for access with the 24 Fr guiding catheter was performed. A total of 72 patients undergoing MitraClip were enrolled in this study (28 patients retrospectively and 44 patients prospectively), of whom 42 patients underwent a groin examination with ultrasound 2 days after the procedure.
  
  
  RESULTS
  Only 1 patient (1.4%) needed transfusion of packed cells because of bleeding and hematoma in the groin due to Proglide failure. None of the patients that were examined with ultrasound revealed an arteriovenous fistula or a spurious aneurysm, a local thrombosis, or a local stenosis related to the Proglide device.
  
  
  CONCLUSIONS
  This study demonstrates that vascular closure with the suture-mediated Proglide system is feasible, safe, and efficacious in large venous sites of 24 Fr as needed in patients undergoing MitraClip implantation despite the necessity of anticoagulation or platelet inhibition.
authors.affiliation: Heart Centre Göttingen - University Medical Centre Göttingen, Cardiology and Pneumology, Robert-Koch-Str. 40, 37099 Göttingen, Germany. schiwolf@med.uni-goettingen.de.
authors.forename: Karin
authors.initials: K
authors.lastname: Rüter
authors.forename: Miriam
authors.initials: M
authors.lastname: Puls
authors.forename: Katrin
authors.initials: K
authors.lastname: von der Ehe
authors.forename: Tobias
authors.initials: T
authors.lastname: Tichelbäcker
authors.forename: Bettina
authors.initials: B
authors.lastname: Sobisiak
authors.forename: Bo Eric
authors.initials: BE
authors.lastname: Beuthner
authors.forename: Mark
authors.initials: M
authors.lastname: Hünlich
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Schillinger
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006328:Cardiac Catheterization / Q000009:adverse effects* / Q000379:methods; D004867:Equipment Design; D005260:Female; D005268:Femoral Vein; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation*; D006489:Hemostatic Techniques / Q000295:instrumentation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000601:surgery*; D011446:Prospective Studies; D012189:Retrospective Studies; D013536:Suture Techniques / Q000295:instrumentation*