title: [Coronary artery disease in Russia: todays reality evidenced by the international CLARIFY registry].
abstract: This paper presents the specific features of clinical manifestation and treatment of coronary heart disease (CHD) in the Russian Federation and compares them to the data from other countries participating in the international CLARIFY (ProspeCtive observational LongitudinAl RegIstry oF patients with stable coronary arterY disease) Registry. In accordance with the exclusion and inclusion criteria, 2249 patients from 43 Russian regions were included in the Registry. Russian patients were younger and had a higher prevalence of risk factors and comorbidities, compared to patients from other countries. In particular, the former more often had cardiovascular disease in family history, smoked (20.9% vs 11.8%; p<0.0001), and had dyslipidemia (77.8% vs 74.6%; p<0.0001) or hypertension (79.6% vs 70.3%; p<0.0001).They also had a higher heart rate (p<0.0001). ). While the incidence of myocardial infarction, based on medical history, was significantly higher than in patients from other countries (78.3% vs 58.4%; p<0.0001), percutaneous coronary intervention (PCI) was performed 2.5 times less often. Particularly striking differences were observed for the prevalence of stable angina and heart failure, which was, respectively, 4.0 and 7.8 times higher in Russian patients, despite the fact that the prescription frequency was similar in the Russian Federation and other countries. These findings should focus Russian doctors attention on the potential ways to solve the problem of "national features" in the treatment of stable CHD.
authors.affiliation: Research Center for Preventive Medicine, Petroverigsky per. 10, 101990 Moscow, Russia.
authors.forename: S A
authors.initials: SA
authors.lastname: Shal'nova
authors.forename: R G
authors.initials: RG
authors.lastname: Oganov
authors.forename: Ph G
authors.initials: PG
authors.lastname: Steg
authors.forename: Ian
authors.initials: I
authors.lastname: Ford
mesh_terms: D002317:Cardiovascular Agents / Q000627:therapeutic use*; D015897:Comorbidity; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D015994:Incidence; D038622:Internationality; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D062645:Percutaneous Coronary Intervention / Q000706:statistics & numerical data*; D012042:Registries; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology; D016019:Survival Analysis
chemical_list: D002317:Cardiovascular Agents