title: The embrace device significantly decreases scarring following scar revision surgery in a randomized controlled trial.
abstract: BACKGROUND
  Mechanically offloading or shielding an incision significantly reduces scarring in both animal and first-in-human studies. Whether or not this strategy would be effective following scar revision surgery was previously unknown. In this article, the authors report that the embrace device, which uses principles of mechanomodulation, significantly improves aesthetic outcomes following scar revision surgery.
  
  
  METHODS
  A prospective, open-label, randomized, single-center study was conducted to evaluate the appearance of scars following revision and embrace treatment. Revision surgery was performed on 12 patients, each acting as his or her own control, and outcomes were assessed at 6 months. A visual analogue scale was used to evaluate each scar, rated by four independent surgeons who were not involved in the study.
  
  
  RESULTS
  Evaluation of 6-month scar images by four independent surgeons using the visual analogue scale demonstrated a highly significant improvement in scar appearance following embrace treatment (p < 0.005).
  
  
  CONCLUSIONS
  The embrace device represents a powerful new technology for significantly improving scar appearance following revision surgery.
  
  
  METHODS
  Therapeutic, II.
authors.affiliation: Palo Alto, Stanford, and Menlo Park, Calif. From the Duet Plastic Surgery Clinic; the Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine; and Neodyne Biosciences, Inc.
authors.forename: Angeline F
authors.initials: AF
authors.lastname: Lim
authors.forename: Jennifer
authors.initials: J
authors.lastname: Weintraub
authors.forename: Ernest N
authors.initials: EN
authors.lastname: Kaplan
authors.forename: Michael
authors.initials: M
authors.lastname: Januszyk
authors.forename: Christy
authors.initials: C
authors.lastname: Cowley
authors.forename: Peggy
authors.initials: P
authors.lastname: McLaughlin
authors.forename: Bill
authors.initials: B
authors.lastname: Beasley
authors.forename: Geoffrey C
authors.initials: GC
authors.lastname: Gurtner
authors.forename: Michael T
authors.initials: MT
authors.lastname: Longaker
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001458:Bandages; D002921:Cicatrix / Q000209:etiology / Q000517:prevention & control* / Q000601:surgery; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012086:Reoperation / Q000009:adverse effects; D012826:Silicone Elastomers; D055815:Young Adult
chemical_list: D012826:Silicone Elastomers