title: [A novel way to induce coronary hyperaemia].
abstract: Coronary angiography and measurement of fractional flow reserve (FFR) are used for anatomical and functional assessment of coronary stenoses. The achievement of maximal coronary hyperaemia is crucial for an accurate calculation of FFR. Although adenosine and papaverine have been well validated, their mechanisms of action as well as methods of administration have some limitations. New and better agents to induce hyperaemia are therefore still being sought. Currently regadenoson, a selective adenosine A2A receptor agonist, seems to possess the characteristics of the almost ‹ideal› hyperaemic stimulus.
authors.affiliation: Klinika Kardiologii i Chorób Wewnętrznych Wojskowego Instytutu Medycznego w Warszawie.
authors.forename: Konrad
authors.initials: K
authors.lastname: Tkaczewski
authors.forename: Mirosław
authors.initials: M
authors.lastname: Dziuk
authors.forename: Janusz
authors.initials: J
authors.lastname: Kocki
authors.forename: Roman
authors.initials: R
authors.lastname: Pińkowski
mesh_terms: D000241:Adenosine; D017023:Coronary Angiography / Q000379:methods; D023921:Coronary Stenosis / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D053805:Fractional Flow Reserve, Myocardial / Q000187:drug effects* / Q000502:physiology*; D006801:Humans; D006940:Hyperemia / Q000139:chemically induced* / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011687:Purines; D011720:Pyrazoles
chemical_list: D011687:Purines; D011720:Pyrazoles; C430916:regadenoson; D000241:Adenosine