title: Oxidative palladium(II)-catalyzed C-7 alkenylation of indolines.
abstract: A mild procedure for C-7-selective C-H alkenylation of various indolines under oxidative palladium(II) catalysis is reported. A fully substituted urea, formed by carbamoylation of the indoline nitrogen atom, functions as a directing group. Both α,β-unsaturated acceptors and styrenes participate in this direct C-H functionalization. With a free NH group at the urea terminus, the nitrogen atom subsequently cyclizes in a 1,4-fashion to yield a six-membered ring.
authors.affiliation: Institut für Chemie, Technische Universität Berlin , Strasse des 17. Juni 115, 10623 Berlin, Germany.
authors.forename: Lin-Yu
authors.initials: LY
authors.lastname: Jiao
authors.forename: Martin
authors.initials: M
authors.lastname: Oestreich