title: Novel device to trend impedance and fluorescence of the cervix for preterm birth detection.
abstract: Preterm birth is the leading cause of worldwide neonatal mortality. It follows a pathologically accelerated form of the normal processes that govern cervical softening and dilation. Softening and dilation occur due to changes in cervical collagen crosslinking, which can be measured non-invasively by changes in tissue fluorescence and impedance. We present a novel device designed specifically to take fluorescence and impedance measurements throughout pregnancy, with the end goal of fusing and trending these measurements to form an early diagnosis of preterm labor.
authors.forename: Mozziyar
authors.initials: M
authors.lastname: Etemadi
authors.forename: Philip
authors.initials: P
authors.lastname: Chung
authors.forename: J Alex
authors.initials: JA
authors.lastname: Heller
authors.forename: Jonathan
authors.initials: J
authors.lastname: Liu
authors.forename: Rebecca
authors.initials: R
authors.lastname: Grossman-Kahn
authors.forename: Larry
authors.initials: L
authors.lastname: Rand
authors.forename: Shuvo
authors.initials: S
authors.lastname: Roy
mesh_terms: D000818:Animals; D002417:Cattle; D002584:Cervix Uteri / Q000502:physiology*; D003094:Collagen / Q000032:analysis; D017097:Electric Impedance; D005260:Female; D005453:Fluorescence; D006176:Gynecology / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D007231:Infant, Newborn; D010865:Pilot Projects; D011247:Pregnancy; D047928:Premature Birth / Q000175:diagnosis*; D012015:Reference Standards
chemical_list: D003094:Collagen