title: Stem cells, tissue engineering and periodontal regeneration.
abstract: The aim of this review is to discuss the clinical utility of stem cells in periodontal regeneration by reviewing relevant literature that assesses the periodontal-regenerative potential of stem cells. We consider and describe the main stem cell populations that have been utilized with regard to periodontal regeneration, including bone marrow-derived mesenchymal stem cells and the main dental-derived mesenchymal stem cell populations: periodontal ligament stem cells, dental pulp stem cells, stem cells from human exfoliated deciduous teeth, stem cells from apical papilla and dental follicle precursor cells. Research into the use of stem cells for tissue regeneration has the potential to significantly influence periodontal treatment strategies in the future.
authors.affiliation: Colgate Australian Clinical Dental Research Centre, School of Dentistry, The University of Adelaide, South Australia.
authors.forename: J
authors.initials: J
authors.lastname: Han
authors.forename: D
authors.initials: D
authors.lastname: Menicanin
authors.forename: S
authors.initials: S
authors.lastname: Gronthos
authors.forename: P M
authors.initials: PM
authors.lastname: Bartold
mesh_terms: D016025:Bone Transplantation; D003739:Dental Cementum / Q000166:cytology; D003782:Dental Pulp / Q000166:cytology; D003795:Dental Sac / Q000166:cytology; D005881:Gingiva / Q000166:cytology; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000627:therapeutic use; D059630:Mesenchymal Stem Cells / Q000166:cytology; D010513:Periodontal Ligament / Q000166:cytology / Q000502:physiology; D010519:Periodontium / Q000196:embryology / Q000293:injuries / Q000502:physiology*; D012038:Regeneration / Q000502:physiology*; D013234:Stem Cells / Q000166:cytology / Q000502:physiology*; D023822:Tissue Engineering; D054457:Tissue Scaffolds; D014094:Tooth, Deciduous / Q000166:cytology; D014945:Wound Healing
chemical_list: D036341:Intercellular Signaling Peptides and Proteins
keywords: Periodontium; bioactive materials; bone grafts; repair; scaffolds