title: Fetal MRI of hereditary multiple intestinal atresia with postnatal correlation.
abstract: Hereditary multiple intestinal atresia (HMIA) is an extremely uncommon cause of congenital bowel obstruction. The morbidity and mortality of this disease differ significantly from those of isolated intestinal atresias and non-hereditary forms of multiple intestinal atresia. Most notably, despite successful operative repairs of the atresias found in this disease, HMIA maintains a 100% lethality rate from continued post-operative intestinal failure and an associated severe immunodeficiency. We present a case of HMIA evaluated with fetal MRI and subsequently diagnosed by a combination of corroborative postnatal imaging with surgical exploration and pathological examination.
authors.affiliation: Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC 5031, Cincinnati, OH, 45229, USA.
authors.forename: Tangayi
authors.initials: T
authors.lastname: Githu
authors.forename: Arnold C
authors.initials: AC
authors.lastname: Merrow
authors.forename: Jason K
authors.initials: JK
authors.lastname: Lee
authors.forename: Aaron P
authors.initials: AP
authors.lastname: Garrison
authors.forename: Rebeccah L
authors.initials: RL
authors.lastname: Brown
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics* / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D007231:Infant, Newborn; D007409:Intestinal Atresia / Q000235:genetics* / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D011296:Prenatal Diagnosis / Q000379:methods*; D013223:Statistics as Topic