title: A new device for the care of Congenital Central Hypoventilation Syndrome patients during sleep.
abstract: Congenital Central Hypoventilation Syndrome (CCHS) is a genetic disease that causes an autonomous nervous system dysregulation. Patients are unable to have a correct ventilation, especially during sleep, facing risk of death. Therefore, most of them are mechanically ventilated during night and their blood oxygenation is monitored, while a supervisor keeps watch over them. If low oxygen levels are detected by the pulse-oximeter, an alarm fires; the supervisor deals with the situation and, if there is neither a technical problem nor a false alarm, wakes the subject, as CCHS patients usually recover from hypoxia when roused from sleep. During a single night multiple alarms may occur, causing fractioned sleep for the subject and a lasting state of anxiety for supervisors.
authors.forename: M
authors.initials: M
authors.lastname: Cavalleri
authors.forename: A
authors.initials: A
authors.lastname: Carcano
authors.forename: F
authors.initials: F
authors.lastname: Morandi
authors.forename: C
authors.initials: C
authors.lastname: Piazza
authors.forename: E
authors.initials: E
authors.lastname: Maggioni
authors.forename: G
authors.initials: G
authors.lastname: Reni
mesh_terms: D006801:Humans; D007040:Hypoventilation / Q000097:blood / Q000151:congenital* / Q000503:physiopathology / Q000628:therapy; D008991:Monitoring, Physiologic; D010092:Oximetry / Q000295:instrumentation*; D010100:Oxygen / Q000097:blood; D012890:Sleep; D020182:Sleep Apnea, Central / Q000097:blood / Q000503:physiopathology / Q000628:therapy*
chemical_list: D010100:Oxygen