title: Cu(II)-catalyzed allylic silylation of Morita-Baylis-Hillman alcohols via dual activation of Si-B bond and hydroxyl group.
abstract: The reaction of Morita-Baylis-Hillman (MBH) alcohols with Me2PhSiBpin under the catalysis of Cu(OTf)2/pyridine in methanol has been developed. The direct silylation of allylic alcohols via dual activation of the Si-B bond and the hydroxyl group of the MBH alcohol provides an efficient and convenient method for the synthesis of functionalized allylsilanes.
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
authors.forename: Qing-Qing
authors.initials: QQ
authors.lastname: Xuan
authors.forename: Neng-Jun
authors.initials: NJ
authors.lastname: Zhong
authors.forename: Chuan-Li
authors.initials: CL
authors.lastname: Ren
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.forename: Dong
authors.initials: D
authors.lastname: Wang
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Chen
authors.forename: Chao-Jun
authors.initials: CJ
authors.lastname: Li
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D012821:Silanes / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D008698:Mesylates; D012821:Silanes; C012077:trifluoromethanesulfonic acid