title: Emergence in Western African countries of MDR-TB, focus on Côte d'Ivoire.
abstract: Tuberculosis (TB) is responsible for a high mortality rate (2.5%) worldwide, mainly in developing countries with a high prevalence of human immunodeficiency virus (HIV). The emergence of multiresistant strains of TB poses an extreme risk for TB outbreaks and highlights the need for global TB control strategies. Among Western African countries, Côte d'Ivoire (CI) represents a specific example of a country with great potential to prevent TB. Specifically, CI has a promising healthcare system for monitoring diseases, including vaccination programs. However, military and political conflict in CI favors the spread of infectious diseases, TB being among the most devastating. Compilation of the studies identifying common causes of TB would be extremely beneficial for the development of treatment and prevention strategies. Therefore, the purpose of this comprehensive review is to evaluate the epidemiology of TB in CI, describe the factors involved in pathogenesis, and suggest simple and applicable prevention strategies.
authors.affiliation: Département de Bactériologie-Virologie, Institut Pasteur de Côte d'Ivoire, 01 BP 490 Abidjan 01, Cote D'Ivoire ; Thérapeutiques Cliniques et Expérimentales des Infections, Département des Maladies Infectieuses UFR de Médecine, 1, rue Gaston Veil, 44035 Nantes Cedex, France.
authors.forename: Euloge
authors.initials: E
authors.lastname: Ekaza
authors.forename: Raymond Kouassi
authors.initials: RK
authors.lastname: N'Guessan
authors.forename: Adèle
authors.initials: A
authors.lastname: Kacou-N'Douba
authors.forename: N'Guetta
authors.initials: N
authors.lastname: Aka
authors.forename: Jacquemin
authors.initials: J
authors.lastname: Kouakou
authors.forename: Françoise
authors.initials: F
authors.lastname: Le Vacon
authors.forename: Fréderic
authors.initials: F
authors.lastname: Altare
authors.forename: Gilles
authors.initials: G
authors.lastname: Potel
authors.forename: Marie-France
authors.initials: MF
authors.lastname: de-La-Cochetiere
mesh_terms: D007560:Cote d'Ivoire / Q000453:epidemiology; D004196:Disease Outbreaks; D006678:HIV / Q000472:pathogenicity; D015658:HIV Infections / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D015995:Prevalence; D018088:Tuberculosis, Multidrug-Resistant / Q000453:epidemiology* / Q000382:microbiology* / Q000821:virology