title: Dentinogenesis Imperfecta : A Family which was Affected for Over Three Generations.
abstract: Dentinogenesis Imperfecta (DI) or hereditary opalescent dentin is inherited in a simple autosomal dominant mode with high penetrance and low mutation rates. It generally affects both the deciduous and the permanent dentitions. DI corresponds to a localized form of mesodermal dysplasia which is observed in the histo-differentiation. An early diagnosis and treatment are therefore fundamental, which aim at obtaining a favourable prognosis, since at late intervention makes the treatment more complex. We are presenting here a case of DI in which the disease affected the three generations of a family in India.
authors.affiliation: Professor & HOD, Paediatric & Preventive Dentistry College of Dental Sciences , Davangere, Karnataka, India .
authors.forename: Poornima
authors.initials: P
authors.lastname: Surendra
authors.forename: Rohan
authors.initials: R
authors.lastname: Shah
authors.forename: Roshan
authors.initials: R
authors.lastname: N M
authors.forename: V V Subba
authors.initials: VV
authors.lastname: Reddy
keywords: Autosomal dominant; Deciduous dentition; Dentinogenesis imperfecta; Opalescent dentin; Osteogenesis imperfecta