title: A survey on the prevalence of Chlamydia trachomatis and Mycoplasma genitalium infections in symptomatic and asymptomatic men referring to urology clinic of labbafinejad hospital, tehran, iran.
abstract: BACKGROUND
  Chlamydia trachomatis and Mycoplasma genitalium infections are the most prevalent sexually transmitted bacterial infections in the world that cause urogenital infections in both men and women. It appears that infertility is a complication of these infections.
  
  
  OBJECTIVE
  This study was designed to estimate the prevalence of Chlamydia trachomatis and Mycoplasma genitalium in symptomatic and asymptomatic men and to assess risk factors associated with infection.
  
  
  METHODS
  Urine specimens were collected from 200 men; 100 of them were symptomatic and 100 asymptomatic. Samples were examined by PCR to detect the infections.
  
  
  RESULTS
  C. trachomatis was detected in 20% of symptomatic and in 4% of asymptomatic men (P < 0.001). The prevalence of M. genitalium was revealed to be 12% and 2% in symptomatic and asymptomatic men, respectively (P < 0.01). Four of 100 men in the symptomatic group were infected with both organisms. C. trachomatis infection was associated with dysuria, urethral discharge, testicular swelling, and genital ulcer (P < 0.05). M. genitalium infection was related with dysuria, testis inflammation, pelvic pain and low educational level (P < 0.05). Furthermore, the prevalence of infections at ages 30-39 years was more than other ages.
  
  
  CONCLUSIONS
  Considering the role of these bacteria in urogenital infections, a screening test is recommended. Since the PCR assay is a highly sensitive and specific assay for the detection of these bacteria in male urine specimens, it provides a noninvasive technique for routine screening.
authors.affiliation: Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, IR Iran.
authors.forename: Omid
authors.initials: O
authors.lastname: Yeganeh
authors.forename: Mahmood
authors.initials: M
authors.lastname: Jeddi-Tehrani
authors.forename: Farhad
authors.initials: F
authors.lastname: Yaghmaie
authors.forename: Kourosh
authors.initials: K
authors.lastname: Kamali
authors.forename: Hamed
authors.initials: H
authors.lastname: Heidari-Vala
authors.forename: Hojjat
authors.initials: H
authors.lastname: Zeraati
authors.forename: Nasser
authors.initials: N
authors.lastname: Shakhssalim
authors.forename: Saeed
authors.initials: S
authors.lastname: Zarei
authors.forename: Leili
authors.initials: L
authors.lastname: Chamani-Tabriz
keywords: Asymptomatic Infections; Chlamydia Trachomatis; Infertility; Mycoplasma Genitalium; Prevalence