title: Genetic testing in children.
abstract: Increasing availability of DNA based tests in clinical practice has lead to widespread debate on the ethical issues involved. The wider usage of these tests in children has raised many questions regarding the ethics, validity of the request and its effects on childs psychosocial well-being. Though there have been much discussion with many studies attempting to address the issue, there is no consensus. Formulation of guidelines has been hampered by the diversity of tests available for varied indications and lack of research studying the effects of testing in children over a time. Some tests have valid indications with proven benefits over harms while others have less clear justification. We attempt to address this issue with the intent to sensitize the caregivers regarding various aspects to be considered before offering any genetic tests in children.
authors.affiliation: Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India. Correspondence to: Dr Shubha Rajendra Phadke, Head of the Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rai Bareilley Road, Lucknow 226 001, Uttar Pradesh, India. shubharaophadke@gmail.com.
authors.forename: Shubha
authors.initials: S
authors.lastname: Phadke
authors.forename: Mamatha
authors.initials: M
authors.lastname: Gowda
mesh_terms: D002648:Child; D005817:Genetic Counseling / Q000941:ethics / Q000379:methods; D005820:Genetic Testing / Q000941:ethics* / Q000379:methods*; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000941:ethics / Q000379:methods; D010372:Pediatrics / Q000941:ethics / Q000379:methods; D011296:Prenatal Diagnosis / Q000941:ethics / Q000379:methods