title: [Multiorgan failure associated with hyperthermia in an infant with Prader-Willi syndrome. case report].
abstract: Heat stroke is a medical emergency characterized primarily by an elevated core temperature associated with a systemic inflammatory response, which causes multiple organ dysfunction in which encephalopathy predominates. If it is not early treated has high mortality. The Prader-Willi syndrome is a multisystem genetic disorder secondary to an abnormality in long arm chromosome 15 (15q11-q13), characterized by neonatal central hypotonia, developmental delay, hypogonadism, hyperphagia and obesity. These patients are susceptible to developing thermoregulatory problems. We report the case of a 5-month-old infant, in whom a diagnosis of Prader-Willi syndrome was established in the course of a febrile episode without known focus, who developed multiorganic failure and rhabdomyolysis secondary to hyperthermia.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Donoso
authors.forename: Daniela
authors.initials: D
authors.lastname: Arriagada
authors.forename: Stephanie
authors.initials: S
authors.lastname: Campbell
authors.forename: Pablo
authors.initials: P
authors.lastname: Cruces
mesh_terms: D005260:Female; D005334:Fever / Q000150:complications*; D006801:Humans; D007223:Infant; D009102:Multiple Organ Failure / Q000209:etiology*; D011218:Prader-Willi Syndrome / Q000150:complications*