title: Minimal change disease in pregnancy.
abstract: BACKGROUND
  New onset minimal change disease (MCD) is rare in pregnancy with the potential for serious complications including acute kidney injury (AKI).
  
  
  METHODS
  A case of MCD was diagnosed at 19 weeks gestation by renal biopsy. Within one month of starting steroids, the patient experienced normalization of renal function and resolution of nephrotic syndrome, although hemodialysis was needed as a temporizing measure.
  
  
  CONCLUSIONS
  The differential diagnosis for new onset proteinuria in pregnancy should include MCD. In selected cases, renal biopsy can be used to confirm diagnosis, and when indicated, hemodialysis should be instituted while awaiting a response to steroid therapy.
authors.affiliation: Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine and.
authors.forename: Jamie O
authors.initials: JO
authors.lastname: Lo
authors.forename: Eric
authors.initials: E
authors.lastname: Kerns
authors.forename: Jose
authors.initials: J
authors.lastname: Rueda
authors.forename: Nicole E
authors.initials: NE
authors.lastname: Marshall
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D009402:Nephrosis, Lipoid / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D009404:Nephrotic Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D011241:Prednisone / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D011262:Pregnancy Trimester, Second
chemical_list: D011241:Prednisone
keywords: Acute kidney injury; minimal change disease; nephrotic syndrome; pregnancy complications; renal disease