title: PedWiz: a web-based tool for pedigree informatics.
abstract: A novel web-based tool PedWiz that pipelines the informatics process for pedigree data is introduced. PedWiz is designed to assist researchers in the analysis of pedigree data. It provides a convenient tool for pedigree informatics: descriptive statistics, relative pairs, genetic similarity coefficients, the variance-covariance matrix for three estimated coefficients of allele identical-by-descent sharing as well as mean allele sharing, a plot of the pedigree structures, and a visualization of the identity coefficients. With a renewed interest in linkage and other family based methods, PedWiz will be a valuable tool for the analysis of family data.
authors.affiliation: Department of Epidemiology and Biostatistics, Case Western Reserve University Cleveland, OH, USA.
authors.forename: Yeunjoo E
authors.initials: YE
authors.lastname: Song
authors.forename: Robert C
authors.initials: RC
authors.lastname: Elston
keywords: family data; genetic similarity; identity-by-descent; informatics; pedigree; relative pairs