title: A novel glucose/pH responsive low-molecular-weight organogel of easy recycling.
abstract: A new phenylboronic acid based gelator was developed to prepare low-molecular-weight organogel (LMOG), which could interact with several solvents to assemble into a three-dimensional nanofiber network. (1)H NMR spectroscopy study suggests that the driving force for the gelation includes hydrogen bonding and π-π stacking. Evaluated by UV-spectroscopy, the gel showed a prompt initial response to glucose at low concentration of 0.012 mmol/mL, which is a critical concentration of venous plasma glucose for diabetes. Significantly, this organogel exhibits excellent sensitivity to glucose among seven sugars tested (i.e., mannitol, galactose, lactose, maltose, sucrose, and fructose). The proposed formation of hydrogen-bonded complexes during the glucose sensing was supported by our energy calculation. Meanwhile, this organogel exhibits pH-response. Importantly, this LMOG could be conveniently recycled and thus be reused.
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University , Wenzhou 325027, China.
authors.forename: Chaoyu
authors.initials: C
authors.lastname: Zhou
authors.forename: Wenxia
authors.initials: W
authors.lastname: Gao
authors.forename: Kaiwen
authors.initials: K
authors.lastname: Yang
authors.forename: Long
authors.initials: L
authors.lastname: Xu
authors.forename: Jinchang
authors.initials: J
authors.lastname: Ding
authors.forename: Jiuxi
authors.initials: J
authors.lastname: Chen
authors.forename: Miaochang
authors.initials: M
authors.lastname: Liu
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Huang
authors.forename: Shun
authors.initials: S
authors.lastname: Wang
authors.forename: Huayue
authors.initials: H
authors.lastname: Wu
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D005782:Gels; D005947:Glucose / Q000032:analysis* / Q000737:chemistry; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D008970:Molecular Weight
chemical_list: D001897:Boronic Acids; D005782:Gels; D005947:Glucose; C010686:benzeneboronic acid