title: Post-filler vascular occlusion: a cautionary tale and emphasis for early intervention.
abstract: We report a case of a 36-year-old female who experienced significant vascular occlusion after injection with hyaluronic acid into the nasolabial folds. The patient experienced immediate pain after the injection, however, the vascular compromise was not diagnosed and treated until 48 hours later. The patient suffered tissue damage despite treatment with hyaluronidase, hyperbaric oxygen, nitropaste, and aspirin. The case highlights the importance of proper injection technique by a qualified physician, as well as the need for immediate recognition and treatment of vascular occlusion should it occur.
authors.forename: Lindsay K
authors.initials: LK
authors.lastname: McGuire
authors.forename: Elizabeth K
authors.initials: EK
authors.lastname: Hale
authors.forename: Loyd S
authors.initials: LS
authors.lastname: Godwin
mesh_terms: D000328:Adult; D001241:Aspirin / Q000627:therapeutic use; D003357:Cosmetic Techniques / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000009:adverse effects*; D006821:Hyaluronoglucosaminidase / Q000627:therapeutic use; D006931:Hyperbaric Oxygenation; D007271:Injections, Intradermal; D060052:Nasolabial Fold; D009336:Necrosis; D010146:Pain / Q000209:etiology; D012871:Skin Diseases / Q000209:etiology / Q000628:therapy; D014652:Vascular Diseases / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology
chemical_list: D006820:Hyaluronic Acid; D006821:Hyaluronoglucosaminidase; D001241:Aspirin