title: Comparing EPI-743 treatment in siblings with Leber's hereditary optic neuropathy mt14484 mutation.
authors.affiliation: Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, Calif.; Federal University of Sao Paulo, Sao Paulo, Brazil.
authors.forename: Carlos F
authors.initials: CF
authors.lastname: Chicani
authors.forename: Edward R
authors.initials: ER
authors.lastname: Chu
authors.forename: Guy
authors.initials: G
authors.lastname: Miller
authors.forename: Shalom E
authors.initials: SE
authors.lastname: Kelman
authors.forename: Alfredo A
authors.initials: AA
authors.lastname: Sadun
mesh_terms: D002648:Child; D004272:DNA, Mitochondrial / Q000235:genetics*; D006801:Humans; D008297:Male; D018977:Micronutrients / Q000627:therapeutic use*; D028361:Mitochondrial Diseases / Q000188:drug therapy* / Q000235:genetics; D009154:Mutation; D029242:Optic Atrophy, Hereditary, Leber / Q000188:drug therapy* / Q000235:genetics; D010375:Pedigree; D016133:Polymerase Chain Reaction; D035781:Siblings; D016896:Treatment Outcome; D014451:Ubiquinone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014792:Visual Acuity / Q000187:drug effects; D014794:Visual Fields / Q000187:drug effects
chemical_list: D004272:DNA, Mitochondrial; D018977:Micronutrients; D014451:Ubiquinone; C571746:alpha-tocotrienol quinone