title: [Case of septic shock caused by extended spectrum β-lactamase producing Escherichia coli after transrectal prostate biopsy, successfully treated by endotoxin adsorption therapy].
abstract: A 62-year-old man, with a family history of prostate cancer, referred to our hospital because of elevated prostate-specific antigen (PSA) (6.02 ng/ml). After prophylactic administration of antibiotics (cefotiam), transrectal needle biopsy of the prostate was performed. He was admitted to the hospital due to high fever the next evening. His blood pressure was below the shock level, and his renal function deteriorated progressively. Suspecting septic shock, the patient was treated with Meropenem, γ-globulin, and dopamine, which were not effective. Then, endotoxin adsorption therapy was employed and the condition of the patient recovered soon after the initiation of the therapy. Extended spectrum β -lactamase-producing Escherichia coli was found in his urine. Pathological diagnosis of the biopsy specimen was atypical glands.
authors.affiliation: The Department of Urology, Saitama Cancer Center.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Kohno
authors.forename: Naotaka
authors.initials: N
authors.lastname: Fukui
authors.forename: Yukio
authors.initials: Y
authors.lastname: Kageyama
authors.forename: Yotsuo
authors.initials: Y
authors.lastname: Higashi
mesh_terms: D001707:Biopsy, Needle / Q000009:adverse effects* / Q000379:methods; D004926:Escherichia coli / Q000201:enzymology / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000209:etiology* / Q000382:microbiology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology*; D012772:Shock, Septic / Q000209:etiology* / Q000382:microbiology / Q000628:therapy*; D016060:Sorption Detoxification / Q000379:methods*; D014556:Urine / Q000382:microbiology; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D001618:beta-Lactamases