title: Multiple cancers in a patient with systemic sclerosis and aggravated interstitial lung disease by chemotherapy.
abstract: Although the relationship between malignancy risk with systemic sclerosis (SSc) has been inconclusive, there are some previous studies for a positive correlation. Most patients with SSc have some degree of lung parenchymal involvement in the form of interstitial thickening and fibrosis. Interstitial lung disease is the most common pulmonary manifestation of SSc. Interstitial lung disease following chemotherapy (5-fluorouracil, leucovorin, and oxaliplatin [FOLFOX]) is an uncommon life-threatening complication and it is induced by oxaliplatin. We report a case of multiple cancers in a patient with SSc and aggravated interstitial lung disease by chemotherapy.
authors.affiliation: Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Chan Kwon
authors.initials: CK
authors.lastname: Park
authors.forename: Seok Jong
authors.initials: SJ
authors.lastname: Lee
authors.forename: Hyung Jun
authors.initials: HJ
authors.lastname: Cho
authors.forename: Kyeong Soo
authors.initials: KS
authors.lastname: Lee
authors.forename: Sung Jun
authors.initials: SJ
authors.lastname: Kim
authors.forename: Gu Min
authors.initials: GM
authors.lastname: Cho
authors.forename: Ha Ni
authors.initials: HN
authors.lastname: Lee
keywords: Lung Diseases, Interstitial; Lung Neoplasms; Scleroderma, Systemic