title: Effects of electro-acupuncture on personality traits in depression: a randomized controlled study.
abstract: OBJECTIVE
  To explore the personality-adjusting effect of electro-acupuncture treatment for depression and compared this treatment with paroxetine treatment.
  
  
  METHODS
  A non-blinded, randomized controlled trial was adopted. Sixty depressed patients, who met trial criteria, were randomly assigned to the treatment and the control groups. In the treatment group, electro-acupuncture treatment was used, and paroxetine treatment was used in the control group. During the 24-week study period, 12 patients dropped out and 48 patients completed the study. The Minnesota Multiple Personality Inventory (MMPI) was adopted as the evaluation tool. At the same time, the Self-rating Depression Scale (SDS), Self-rating Anxiety Scale (SAS) and Montgomery-Asberg Depression Rating Scale (MADRS) were used to evaluate the psychological state. Evaluations were done before and after treatment.
  
  
  RESULTS
  After treatment, patients' psychological state improved significantly in both groups (P<0.01). For the treatment group, within-group comparison between baseline and after 24 weeks of treatment showed that severity of depression had significantly decreased (P<0.01). MADRS and SDS scores decreased significantly (P<0.05) and MMPI subscale scores for hypochondriasis, depression, psychopathic deviate, psychasthenia, social introversion and fake decreased significantly (P<0.05). For the control group, severity of depression also decreased significantly. MADRS and SDS scores decreased significantly (P<0.05); and MMPI subscale scores for hypochondriasis, depression, hysteria, paranoia, and psychasthenia decreased significantly (P<0.05). Between-group comparison demonstrated that for the MMPI subscales paranoia and social introversion, the decrease of score was greater in the treatment group than in the control group (P<0.05). However, there were no other significant differences between the control group and the treatment group.
  
  
  CONCLUSIONS
  Electro-acupuncture is effective for treating depression and affects personality traits.
authors.affiliation: Department of Psychology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China, prof_wwd@126.com.
authors.forename: Wei-dong
authors.initials: WD
authors.lastname: Wang
authors.forename: Xue-yu
authors.initials: XY
authors.lastname: Lu
authors.forename: Siu-man
authors.initials: SM
authors.lastname: Ng
authors.forename: Lan
authors.initials: L
authors.lastname: Hong
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhao
authors.forename: Ying-na
authors.initials: YN
authors.lastname: Lin
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
mesh_terms: D016022:Case-Control Studies; D003710:Demography; D003863:Depression / Q000188:drug therapy / Q000523:psychology* / Q000628:therapy*; D015671:Electroacupuncture; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017374:Paroxetine / Q000627:therapeutic use; D010352:Patient Dropouts; D010551:Personality; D010555:Personality Inventory; D011569:Psychiatric Status Rating Scales
chemical_list: D017374:Paroxetine