title: Host and viral transcriptional regulators in Sulfolobus: an overview.
abstract: The genus Sulfolobus includes microorganisms belonging to the domain Archaea, sub-kingdom Crenarchaeota, living in geographically distant acidic hot springs. Their adaptation to such particular habitats requires finely regulated mechanisms of gene expression, among which, those modulated by sequence-specific transcription factors (TFs) play a key role. In this review, we summarize the current knowledge on the repertoires of TFs found in Sulfolobus spp. and their viruses, focusing on the description of their DNA-binding domains and their structure-function relationship.
authors.affiliation: Dipartimento di Biologia, Università di Napoli Federico II, via Cinthia, Edificio 7, 80126, Napoli, Italy.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Contursi
authors.forename: Salvatore
authors.initials: S
authors.lastname: Fusco
authors.forename: Danila
authors.initials: D
authors.lastname: Limauro
authors.forename: Gabriella
authors.initials: G
authors.lastname: Fiorentino
mesh_terms: D000595:Amino Acid Sequence; D019843:Archaeal Proteins / Q000737:chemistry* / Q000378:metabolism; D023641:Archaeal Viruses / Q000378:metabolism* / Q000472:pathogenicity; D008969:Molecular Sequence Data; D016944:Sulfolobus / Q000378:metabolism* / Q000821:virology; D014157:Transcription Factors / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D014764:Viral Proteins / Q000737:chemistry* / Q000378:metabolism
chemical_list: D019843:Archaeal Proteins; D014157:Transcription Factors; D014764:Viral Proteins