title: Effects of continuous positive airway pressure therapy in three Japanese patients with obstructive sleep apnea and resistant hypertension.
abstract: The following three case reports present the effects of 6-month continuous positive airway pressure (CPAP) therapy on blood pressure (BP) in severe obstructive sleep apnea patients with resistant hypertension. Case 1 A 58-year-old woman exhibited a decreased 24-hour BP and changes in the nocturnal BP dipping pattern from non-dipper to dipper. Case 2 A 64-year-old man showed no improvements in nocturnal BP. Case 3 A 78-year-old man with ischemic cardiomyopathy exhibited changes in the nocturnal BP dipping pattern from non-dipper to dipper. These results suggest that 6-month CPAP therapy improves the nocturnal BP dipping status in some patients with obstructive sleep apnea and resistant hypertension.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Japan.
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Sekizuka
authors.forename: Naohiko
authors.initials: N
authors.lastname: Osada
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Miyake
mesh_terms: D000368:Aged; D044466:Asian People; D001794:Blood Pressure / Q000502:physiology; D045422:Continuous Positive Airway Pressure / Q000379:methods*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome