title: Palladium catalyzed oxidative coupling of α-enolic dithioesters: a new entry to 3,4,5-trisubstituted 1,2-dithioles via a double activation strategy.
abstract: An operationally simple, facile, and convenient one-pot straightforward method for the construction of 3,4,5-trisubstituted 1,2-dithioles has been explored and developed via palladium catalyzed self-coupling of α-enolic dithioesters for the first time. Pd(0) efficiently catalyzes the activation and cleavage of S-H and C-S bonds to achieve cascade coupling, which results in the concomitant formation of new S-S and C-C bonds. Optimization data, substrate scope, and mechanistic insights are discussed.
authors.affiliation: Department of Chemistry, Faculty of Science, Banaras Hindu University , Varanasi-221005, India, and Department of Chemistry, Loughborough University , Loughborough, Leicestershire LE11 3TU, U.K.
authors.forename: Sushobhan
authors.initials: S
authors.lastname: Chowdhury
authors.forename: Tanmoy
authors.initials: T
authors.lastname: Chanda
authors.forename: Suvajit
authors.initials: S
authors.lastname: Koley
authors.forename: B Janaki
authors.initials: BJ
authors.lastname: Ramulu
authors.forename: Raymond C F
authors.initials: RC
authors.lastname: Jones
authors.forename: Maya Shankar
authors.initials: MS
authors.lastname: Singh