title: Ocular manifestation of lymphoma in newly diagnosed cats.
abstract: Ocular manifestations of lymphoma are described in humans and dogs but rarely in cats. In this prospective study, cats with newly diagnosed and treatment-naïve lymphoma were evaluated concerning clinical stage and ophthalmologic findings. Twenty-six cats were included. In 12 cats (48%), ocular changes were documented. Uveitis anterior and posterior were predominant findings, being present in 58% of affected individuals. Other findings included exophthalmos, corneal surface lesions and chemosis. Eight cats received chemotherapy, two of which had ocular involvement. In these two cats, a complete remission of an anterior and a partial remission of a posterior uveitis were documented. Due to the detection of ocular involvement, a stage migration from stage IV to V occurred in four patients. In the light of these findings, an opthalmological examination may be considered as an important part of staging in feline lymphoma as well as of follow-up examination in affected cats.
authors.affiliation: Small Animal Hospital, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
authors.forename: V
authors.initials: V
authors.lastname: Nerschbach
authors.affiliation: Small Animal Clinic, Faculty of Veterinary Medicine, Freie Universität, Berlin, Germany.
authors.forename: J C
authors.initials: JC
authors.lastname: Eule
authors.affiliation: Small Animal Hospital, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
authors.forename: N
authors.initials: N
authors.lastname: Eberle
authors.affiliation: Small Animal Hospital, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Höinghaus
authors.affiliation: Small Animal Hospital, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Betz
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D002415:Cats; D005128:Eye Diseases / Q000209:etiology / Q000662:veterinary*; D008223:Lymphoma / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D009367:Neoplasm Staging / Q000662:veterinary; D011446:Prospective Studies
keywords: chemotherapy; eye; feline; stage migration; uveitis