title: Systemic allergic dermatitis caused by Apiaceae root vegetables.
abstract: BACKGROUND
  Immediate hypersensitivity reactions to root vegetables of the Umbelliferae plant family (Apiaceae) is well known. Delayed-type hypersensitivity is rarely reported.
  
  
  OBJECTIVE
  To report the first case of systemic contact dermatitis caused by root vegetables and some chemical implications.
  
  
  METHODS
  Prick and patch testing were performed with fresh vegetables and selected allergens, and this was followed by high-performance liquid chromatography-mass spectrometry (MS)/MS analysis of the falcarinol syringe.
  
  
  RESULTS
  The patient was contact-sensitive to celeriac, parsnip, and carrot, but tested negative to falcarinol. Subsequent analysis showed that the syringe contained falcarinol.
  
  
  CONCLUSIONS
  The non-occupational sensitization resulting from both direct and systemic contact with Apiaceae root vegetables was apparently not caused by falcarinol.
authors.affiliation: Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, DK-5000, Odense C, Denmark.
authors.forename: Evy
authors.initials: E
authors.lastname: Paulsen
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Petersen
authors.forename: Xavier C
authors.initials: XC
authors.lastname: Fretté
authors.forename: Klaus E
authors.initials: KE
authors.lastname: Andersen
authors.forename: Lars P
authors.initials: LP
authors.lastname: Christensen
mesh_terms: D000328:Adult; D000077102:Apium / Q000009:adverse effects; D003231:Conjunctivitis / Q000209:etiology; D018552:Daucus carota / Q000009:adverse effects; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D053280:Diynes / Q000009:adverse effects; D005233:Fatty Alcohols / Q000009:adverse effects; D005260:Female; D005512:Food Hypersensitivity / Q000209:etiology*; D006229:Hand Dermatoses / Q000139:chemically induced / Q000209:etiology; D006801:Humans; D028529:Pastinaca / Q000009:adverse effects; D010328:Patch Tests; D012220:Rhinitis / Q000209:etiology; D013280:Stomatitis / Q000209:etiology; D014675:Vegetables / Q000009:adverse effects*
chemical_list: D053280:Diynes; D005233:Fatty Alcohols; C018541:falcarinol
keywords: Apiacae; Apium graveolens var. rapaceum; Daucus carota; Pastinaca sativa; allergic contact dermatitis; carrot; celeriac; parsnip; patch testing; systemic allergic dermatitis