title: Ductal carcinoma in situ of the breasts: review of MR imaging features.
abstract: The incidence of ductal carcinoma in situ (DCIS) has increased over the past few decades and now accounts for over 20% of newly diagnosed cases of breast cancer. Although the detection of DCIS has increased with the advent of widespread mammography screening, it is essential to have a more accurate assessment of the extent of DCIS for successful breast conservation therapy. Recent studies evaluating the detection of DCIS with magnetic resonance (MR) imaging have used high spatial resolution techniques and have increasingly been performed to screen a high-risk population as well as to evaluate the extent of disease. This work has shown that MR imaging is the most sensitive modality currently available for identifying DCIS and is more accurate than mammography in evaluating the extent of DCIS. MR imaging is particularly sensitive for identifying high-grade and intermediate-grade DCIS. DCIS may have variable morphologic features on MR images, with non-mass enhancement morphology being the most common manifestation. Less commonly, DCIS may also manifest as a mass on MR images, in which case it is most likely to be irregular. The kinetics of DCIS are also variable, with fast uptake and a plateau curve reported as the most common kinetic pattern. Additional MR imaging tools such as diffusion-weighted imaging and quantitative kinetic analysis combined with the benefit of high field strength, such as 3 T, may increase the sensitivity and specificity of breast MR imaging in the detection of DCIS.
authors.affiliation: Department of Radiology, New York University School of Medicine, 550 First Ave, New York, NY 10016.
authors.forename: Heather I
authors.initials: HI
authors.lastname: Greenwood
authors.forename: Samantha L
authors.initials: SL
authors.lastname: Heller
authors.forename: Sungheon
authors.initials: S
authors.lastname: Kim
authors.forename: Eric E
authors.initials: EE
authors.lastname: Sigmund
authors.forename: Sara D
authors.initials: SD
authors.lastname: Shaylor
authors.forename: Linda
authors.initials: L
authors.lastname: Moy
mesh_terms: D001706:Biopsy; D001943:Breast Neoplasms / Q000175:diagnosis*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis*; D003287:Contrast Media; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008327:Mammography; D012680:Sensitivity and Specificity; D016217:Ultrasonography, Mammary
chemical_list: D003287:Contrast Media