title: A near-infrared dye based on BODIPY for tracking morphology changes in mitochondria.
abstract: M-DPT, a BODIPY-based water soluble near-infrared fluorescent probe with thiophene at the 1,7-position, is synthesized. M-DPT is found to possess high specificity to mitochondria, superior photostability, and appreciable tolerance to microenvironmental changes. Thus, this probe is a highly suitable imaging agent for targeting mitochondria and tracking morphology changes.
authors.affiliation: State Key Laboratory of Fine Chemicals, Dalian University of Technology, No. 2 Linggong Road, High-Tech District, Dalian 116024, China. fanjl@dlut.edu.cn pengxj@dlut.edu.cn.
authors.forename: Na
authors.initials: N
authors.lastname: Jiang
authors.forename: Jiangli
authors.initials: J
authors.lastname: Fan
authors.forename: Tao
authors.initials: T
authors.lastname: Liu
authors.forename: Jianfang
authors.initials: J
authors.lastname: Cao
authors.forename: Bo
authors.initials: B
authors.lastname: Qiao
authors.forename: Jingyun
authors.initials: J
authors.lastname: Wang
authors.forename: Pan
authors.initials: P
authors.lastname: Gao
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Peng
mesh_terms: D001896:Boron Compounds / Q000737:chemistry* / Q000378:metabolism; D003584:Cytological Techniques / Q000379:methods*; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D007259:Infrared Rays; D061986:MCF-7 Cells; D018613:Microscopy, Confocal; D008928:Mitochondria / Q000378:metabolism / Q000502:physiology*; D011726:Pyridinium Compounds / Q000737:chemistry* / Q000378:metabolism; D011789:Quantum Theory; D013329:Structure-Activity Relationship
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D005456:Fluorescent Dyes; D011726:Pyridinium Compounds