title: Comment: infection antedating autoimmunity-- shared mechanisms in the brain?
abstract: Anti-NMDA receptor (NMDAR) encephalitis is a well-recognized immunotherapy-responsive condition, often diagnosed in younger individuals with characteristic clinical symptoms. In women, ovarian teratomas are frequently found and thought to trigger the antibody response against the NMDAR by ectopically expressing neuronal antigens. The present study describes the case of a patient with HSV encephalitis (HSVE) who develops a second episode of neurologic abnormalities, which is in fact NMDAR encephalitis.(1.)
authors.affiliation: From Charité University Medicine Berlin and German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.
authors.forename: Harald
authors.initials: H
authors.lastname: Prüss
mesh_terms: D060426:Anti-N-Methyl-D-Aspartate Receptor Encephalitis / Q000209:etiology / Q000276:immunology / Q000821:virology; D015551:Autoimmunity; D001921:Brain / Q000473:pathology* / Q000821:virology*; D018792:Encephalitis, Viral / Q000150:complications*; D006801:Humans; D012189:Retrospective Studies; D018139:Simplexvirus / Q000472:pathogenicity