title: Substrate-induced rearrangements in glutamate-transporter homologs.
abstract: Sodium-coupled glutamate transporters regulate excitatory signaling in the brain. A new crystal structure shows how the substrate induces changes in the binding pocket of an archaeal transporter homolog, providing new insights into the mechanism of transport.
authors.affiliation: Department of Biochemistry and Molecular Biology, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
authors.forename: Baruch I
authors.initials: BI
authors.lastname: Kanner
mesh_terms: D001224:Aspartic Acid / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*
chemical_list: D002352:Carrier Proteins; D001224:Aspartic Acid