title: A randomized controlled trial comparing health and quality of life of lung transplant recipients following nurse and computer-based triage utilizing home spirometry monitoring.
abstract: BACKGROUND
  Lung transplantation is now a standard intervention for patients with advanced lung disease. Home monitoring of pulmonary function and symptoms has been used to follow the progress of lung transplant recipients in an effort to improve care and clinical status. The study objective was to determine the relative performance of a computer-based Bayesian algorithm compared with a manual nurse decision process for triaging clinical intervention in lung transplant recipients participating in a home monitoring program.
  
  
  METHODS
  This randomized controlled trial had 65 lung transplant recipients assigned to either the Bayesian or nurse triage study arm. Subjects monitored and transmitted spirometry and respiratory symptoms daily to the data center using an electronic spirometer/diary device. Subjects completed the Short Form-36 (SF-36) survey at baseline and after 1 year. End points were change from baseline after 1 year in forced expiratory volume at 1 s (FEV1) and quality of life (SF-36 scales) within and between each study arm.
  
  
  RESULTS
  There were no statistically significant differences between groups in FEV1 or SF-36 scales at baseline or after 1 year.: Results were comparable between nurse and Bayesian system for detecting changes in spirometry and symptoms, providing support for using computer-based triage support systems as remote monitoring triage programs become more widely available.
  
  
  CONCLUSIONS
  The feasibility of monitoring critical patient data with a computer-based decision system is especially important given the likely economic constraints on the growth in the nurse workforce capable of providing these early detection triage services.
authors.affiliation: 1 Department of Laboratory Medicine and Pathology/Health Informatics, University of Minnesota , Minneapolis, Minnesota.
authors.forename: Stanley M
authors.initials: SM
authors.lastname: Finkelstein
authors.forename: Bruce R
authors.initials: BR
authors.lastname: Lindgren
authors.forename: William
authors.initials: W
authors.lastname: Robiner
authors.forename: Ruth
authors.initials: R
authors.lastname: Lindquist
authors.forename: Marshall
authors.initials: M
authors.lastname: Hertz
authors.forename: Bradley P
authors.initials: BP
authors.lastname: Carlin
authors.forename: Arin
authors.initials: A
authors.lastname: VanWormer
mesh_terms: D000328:Adult; D000368:Aged; D003658:Decision Making, Computer-Assisted; D005260:Female; D006304:Health Status; D006699:Home Care Services; D006801:Humans; D016040:Lung Transplantation / Q000451:nursing; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods*; D011788:Quality of Life; D013147:Spirometry; D066027:Transplant Recipients; D014218:Triage / Q000379:methods*; D055815:Young Adult