title: Applications of organoboron compounds in carbohydrate chemistry and glycobiology: analysis, separation, protection, and activation.
abstract: The reversible covalent interactions between organoboron compounds and diols have been applied for many years in carbohydrate chemistry. They form the basis of efficient methods for the detection of carbohydrates, and applications in cellular imaging and glycoprotein analysis are beginning to emerge. The interactions are also of widespread utility in carbohydrate synthesis: depending upon the coordination geometry at boron, either protection or activation of a bound diol motif may be achieved. This review article uses recent examples to illustrate the breadth of applications of organoboron compounds in carbohydrate chemistry.
authors.affiliation: Department of Chemistry, University of Toronto, 80 St. George St., Toronto, ON M5S 3H6, Canada.
authors.forename: Corey A
authors.initials: CA
authors.lastname: McClary
authors.forename: Mark S
authors.initials: MS
authors.lastname: Taylor
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D002241:Carbohydrates / Q000032:analysis*; D054794:Glycomics; D006023:Glycoproteins / Q000032:analysis*; D015394:Molecular Structure
chemical_list: D001896:Boron Compounds; D002241:Carbohydrates; D006023:Glycoproteins
keywords: Boronic acids; Carbohydrates; Catalysis; Drug delivery; Fluorescence; Glycosylation