title: Minireview: applied structural bioinformatics in proteomics.
abstract: The limited sequence similarity of protein sequences with known structures has led to an indispensable need for computational technology to predict their structures. Structural bioinformatics (SB) has become integral in elucidating the sequence-structure-function relationship of a protein. This report focuses on the applications of SB within the context of protein engineering including its limitation and future challenges.
authors.affiliation: Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800, Minden, Pulau Pinang, Malaysia, yeesiew@usm.my.
authors.forename: Yee Siew
authors.initials: YS
authors.lastname: Choong
authors.forename: Gee Jun
authors.initials: GJ
authors.lastname: Tye
authors.forename: Theam Soon
authors.initials: TS
authors.lastname: Lim
mesh_terms: D000595:Amino Acid Sequence; D056004:Molecular Dynamics Simulation; D008969:Molecular Sequence Data; D011487:Protein Conformation; D015202:Protein Engineering; D060066:Protein Interaction Maps; D011506:Proteins / Q000737:chemistry*; D040901:Proteomics
chemical_list: D011506:Proteins