title: Alcohol Consumption and Breast Cancer Survival: A Meta- analysis of Cohort Studies.
abstract: OBJECTIVE
  Evidence for associations between alcohol consumption with breast cancer survival are conflicting, so we conducted the present meta-analysis.
  
  
  METHODS
  Comprehensive searches were conducted to find cohort studies that evaluated the relationship between alcohol consumption with breast cancer survival. Data were analyzed with meta-analysis software.
  
  
  RESULTS
  We included 25 cohort studies. The meta-analysis results showed that alcohol consumption was not associated with increased breast cancer mortality and recurrence after pooling all data from highest versus lowest comparisons. Subgroup analyses showed that pre-diagnostic or post-diagnostic consumpotion, and ER status did not affect the relationship with breast cancer mortality and recurrence. Although the relationships of different alcohol consumption with breast cancer mortality and recurrence were not significant, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence. Only alcohol consumption of >20 g/d was associated with increased breast cancer mortality, but not with increased breast cancer recurrence.
  
  
  CONCLUSIONS
  Although our meta-analysis showed alcohol drinking was not associated with increased breast cancer mortality and recurrence, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence and alcohol consumption of >20 g/d was associated with increased breast cancer mortality.
authors.affiliation: Department of Thoracic Surgery, Lanzhou University, Second Hospital, Lanzhou, Gansu Province, China E-mail : hexiaodong2006@126.com.
authors.forename: Yun-Jiu
authors.initials: YJ
authors.lastname: Gou
authors.forename: Ding-Xiong
authors.initials: DX
authors.lastname: Xie
authors.forename: Ke-Hu
authors.initials: KH
authors.lastname: Yang
authors.forename: Ya-Li
authors.initials: YL
authors.lastname: Liu
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Zhang
authors.forename: Bin
authors.initials: B
authors.lastname: Li
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: He
mesh_terms: D000428:Alcohol Drinking / Q000401:mortality*; D001943:Breast Neoplasms / Q000401:mortality*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000401:mortality*; D011379:Prognosis; D015996:Survival Rate