title: Small vessel disease and memory loss: what the clinician needs to know to preserve patients' brain health.
abstract: Small vessel disease (SVD) in the brain manifests in the periventricular and deep white matter and radiographically is described as "leukoaraiosis". It is increasingly recognized as a cause of morbidity from middle age onward and this clinical relevance has paralleled advances in the field of neuroradiology. Overall, SVD is a heterogenous group of vascular disorders that may be asymptomatic, or a harbinger of many conditions that jeopardize brain health. Management and prevention focuses on blood pressure control, lifestyle modification, and symptomatic treatment.
authors.affiliation: Department of Neurology, University Hospitals Case Medical Center, 3619 Park East Drive, suite 211, Beachwood, OH, 44122, USA.
authors.forename: Christian
authors.initials: C
authors.lastname: Schenk
authors.forename: Timothy
authors.initials: T
authors.lastname: Wuerz
authors.forename: Alan J
authors.initials: AJ
authors.lastname: Lerner
mesh_terms: D001794:Blood Pressure / Q000187:drug effects; D002560:Cerebrovascular Circulation; D015140:Dementia, Vascular / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D049292:Leukoaraiosis / Q000150:complications / Q000503:physiopathology*; D008297:Male; D008569:Memory Disorders / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control; D008833:Microcirculation; D011788:Quality of Life; D040242:Risk Reduction Behavior; D009626:Terminology as Topic