title: Quantitative elastography and its application to blood pressure estimation: theoretical and experimental results.
abstract: Elastography is a method that can be used to measure the elasticity of soft biological tissue and, ultimately, to detect cancerous tumors. In this paper, quantitative elastography is developed using a fast multi-scale approach. Results are presented in simulation and preliminary results are presented in experiment. The optimization methods of elastography are applied to measure noninvasively the arterial wall stiffness of a vessel as well as blood pressure. Simulation results are presented that confirm the accuracy of methods, and preliminary experimental results are presented that measure pressure within a cylindrical cavity in a phantom. Using ultrasound, these methods could provide noninvasive continuous measurement of blood pressure in major arteries and could give doctors another method with which to gather information about a patient's cardiovascular health.
authors.forename: Aaron M
authors.initials: AM
authors.lastname: Zakrzewski
authors.forename: Brian W
authors.initials: BW
authors.lastname: Anthony
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination / Q000379:methods*; D003198:Computer Simulation; D054459:Elasticity Imaging Techniques / Q000379:methods*; D007091:Image Processing, Computer-Assisted; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging