title: Phaeochromocytoma [corrected] crisis.
abstract: Phaeochromocytoma [corrected] crisis is an endocrine emergency associated with significant mortality. There is little published guidance on the management of phaeochromocytoma [corrected] crisis. This clinical practice update summarizes the relevant published literature, including a detailed review of cases published in the past 5 years, and a proposed classification system. We review the recommended management of phaeochromocytoma [corrected] crisis including the use of alpha-blockade, which is strongly associated with survival of a crisis. Mechanical circulatory supportive therapy (including intra-aortic balloon pump or extra-corporeal membrane oxygenation) is strongly recommended for patients with sustained hypotension. Surgical intervention should be deferred until medical stabilization is achieved.
authors.affiliation: King's College Hospital - Endocrinology, London, UK.
authors.forename: B C
authors.initials: BC
authors.lastname: Whitelaw
authors.forename: J K
authors.initials: JK
authors.lastname: Prague
authors.forename: O G
authors.initials: OG
authors.lastname: Mustafa
authors.forename: K-M
authors.initials: KM
authors.lastname: Schulte
authors.forename: P A
authors.initials: PA
authors.lastname: Hopkins
authors.forename: J A
authors.initials: JA
authors.lastname: Gilbert
authors.forename: A M
authors.initials: AM
authors.lastname: McGregor
authors.forename: S J B
authors.initials: SJ
authors.lastname: Aylwin
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000188:drug therapy* / Q000503:physiopathology; D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D006801:Humans; D010673:Pheochromocytoma / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000317:Adrenergic alpha-Antagonists