title: Feasibility and early safety of hybrid coronary revascularisation combining off-pump coronary surgery through J-hemisternotomy with percutaneous coronary intervention.
abstract: OBJECTIVE
  To assess the procedural feasibility and early safety of hybrid coronary revascularisation, combining off-pump left internal mammary artery grafting to the left descending coronary artery (LAD) through an inferior J-hemisternotomy (JOPCAB) with percutaneous coronary intervention (PCI) of non-LAD lesions.
  
  
  RESULTS
  A total of 100 patients with multivessel coronary artery disease involving LAD were included in this prospective registry. Hybrid revascularisation was performed by JOPCAB, either prior to PCI (89%) or following PCI (11%). In 96% of the cases, the procedure was carried out according to the preoperative strategy and without perioperative (24 hours) major adverse cardiac or cerebral events. At one month, we observed no deaths, one stroke and two procedure-related myocardial infarctions. Five patients underwent reoperation for graft dysfunction, four of whom were identified by angiography without prior signs of ischaemia. Reoperation due to bleeding was necessary in six patients, and nine patients received red blood cell transfusion.
  
  
  CONCLUSIONS
  Our prospective registry documented promising procedural feasibility and early safety of coronary hybrid revascularisation combining JOPCAB with PCI. ClinicalTrials.gov identifier: NCT01496664.
authors.affiliation: Department of Cardiothoracic Surgery, Aarhus University Hospital, Skejby, Aarhus, Denmark.
authors.forename: Ivy S
authors.initials: IS
authors.lastname: Modrau
authors.forename: Per H
authors.initials: PH
authors.lastname: Nielsen
authors.forename: Hans E
authors.initials: HE
authors.lastname: Bøtker
authors.forename: Evald H
authors.initials: EH
authors.lastname: Christiansen
authors.forename: Lars R
authors.initials: LR
authors.lastname: Krusell
authors.forename: Anne K
authors.initials: AK
authors.lastname: Kaltoft
authors.forename: Michael
authors.initials: M
authors.lastname: Mæng
authors.forename: Christian J
authors.initials: CJ
authors.lastname: Terkelsen
authors.forename: Steen D
authors.initials: SD
authors.lastname: Kristensen
authors.forename: Jens F
authors.initials: JF
authors.lastname: Lassen
authors.forename: Leif
authors.initials: L
authors.lastname: Thuesen
mesh_terms: D054058:Acute Coronary Syndrome / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D060050:Angina, Stable / Q000601:surgery*; D015331:Cohort Studies; D003131:Combined Modality Therapy; D047549:Coronary Artery Bypass, Off-Pump / Q000379:methods*; D003324:Coronary Artery Disease / Q000601:surgery; D054059:Coronary Occlusion / Q000601:surgery*; D023921:Coronary Stenosis / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006470:Hemorrhage / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology; D061646:Operative Time; D062645:Percutaneous Coronary Intervention / Q000379:methods*; D011183:Postoperative Complications / Q000453:epidemiology; D011446:Prospective Studies; D012042:Registries; D012086:Reoperation; D056346:Sternotomy / Q000379:methods