title: Effect of a lifestyle therapy program using cardiac rehabilitation resources on metabolic syndrome components.
abstract: OBJECTIVE
  To assess the effect of a lifestyle therapy program using cardiac rehabilitation (CR) resources for patients at risk for metabolic syndrome (MetS).
  
  
  METHODS
  We designed a cardiometabolic program (CMP) using CR facilities and resources. We compared MetS components of 240 patients classified as either obese (body mass index, ≥30 kg/m) or hyperglycemic (fasting glucose, >100 mg/dL): 58 enrolled and completed the CMP, 59 signed up for the CMP but never attended or dropped out early (control 1) but had followup data, and 123 did not sign up for the CMP (control 2).
  
  
  RESULTS
  The CMP group showed a significant improvement at 6 weeks in waist circumference, body weight, diastolic blood pressure, and total cholesterol. At 6 months, fasting glucose also improved. In contrast, improvements in control 1 and control 2 were modest at best. Comparing the 6-month changes in the CMP group versus control 1 group, those in the CMP had pronounced weight loss (-4.5 ± 5 kg vs. -0.14 ± 6 kg; P < .001), decreased systolic blood pressure (-1.1 ± 17 mm Hg vs. +9.6 ± 20 mm Hg; P = .004), and decreased diastolic blood pressure (-4.6 ± 11 mm Hg vs. +3.4 ± 15 mm Hg; P = .002). Similarly, comparing CMP group versus control 2 group, body weight (-4.5 ± 5 kg vs. -0.9 ± 3 kg; P < .001) and diastolic blood pressure (-4.6 ± 11 mm Hg vs. -0.7 ± 9 mm Hg; P = .02) declined in the CMP group.
  
  
  CONCLUSIONS
  A lifestyle therapy program using resources of a CR program is effective for individuals who have or are at risk for MetS, although enrollment and completion rates are low.
authors.affiliation: Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota (Drs Rodriguez-Escudero, Somers, Thomas, Squires, Sochor, and Lopez-Jimenez and Ms Heath); and Department of Cardiovascular Diseases, International Clinic Research Center, St Anne's University Hospital Brno, Brno, Czech Republic (Dr Sochor).
authors.forename: Juan P
authors.initials: JP
authors.lastname: Rodriguez-Escudero
authors.forename: Virend K
authors.initials: VK
authors.lastname: Somers
authors.forename: Amy L
authors.initials: AL
authors.lastname: Heath
authors.forename: Randal J
authors.initials: RJ
authors.lastname: Thomas
authors.forename: Ray W
authors.initials: RW
authors.lastname: Squires
authors.forename: Ondrej
authors.initials: O
authors.lastname: Sochor
authors.forename: Francisco
authors.initials: F
authors.lastname: Lopez-Jimenez
mesh_terms: D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D015992:Body Mass Index; D001835:Body Weight; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008019:Life Style; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000503:physiopathology / Q000534:rehabilitation*; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D001786:Blood Glucose