title: HBsAg Positive Patient Characteristics in Hospital and Blood Donation Camps.
abstract: Background. Prevention of the residual risk of transfusion transmitted hepatitis B virus infection (HBV) is mostly dependant on serological screening of blood donors for HBsAg and antibody to hepatitis B core antigen (anti-HBc Ab). This study aimed to study the prevalence of HBsAg and anti-HBc Ab and to compare the profile of blood donors attending a blood donation camp and people attending a hospital based camp. Methods. In the blood donor camp, all the blood units were screened for HBV, (HBsAg and anti-HBc), and in the hospital based camp, screening was done for HBsAg alone. Baseline demographic characteristics were noted. Results. The number of blood bank donors was 363 (47.5%) and hospital camp attendees was 402 (52.5%). Prevalence of HBsAg positivity was similar in both the groups at 1.7% and 1.9%, respectively. Anti-HBc Ab positivity (Total) was 6% among the blood donors; Overall prevalence of HBV infection in this group was 3.2%. Conclusion. Policy for checking the collected blood unit by 3 tests for anti-HBc, anti-HBsAb, and HBsAg should be reconsidered to possibly achieve the zero risk goal of transfusion transmitted HBV infection. Blood obtained from a vaccinated donor may give an added protection to the recipient.
authors.affiliation: Department of Transfusion Medicine, Global Hospitals & Health City, Chennai, India.
authors.forename: Deepti
authors.initials: D
authors.lastname: Sachan
authors.forename: Joy
authors.initials: J
authors.lastname: Varghese
authors.forename: Jensingh
authors.initials: J
authors.lastname: Joseph
authors.forename: Vijaya
authors.initials: V
authors.lastname: Srinivasan
authors.forename: Venkataraman
authors.initials: V
authors.lastname: Jayanthi
authors.forename: Mohamed
authors.initials: M
authors.lastname: Rela