title: How the devil facial tumor disease escapes host immune responses.
abstract: The devil facial tumor disease (DFTD) is a contagious cancer that has recently emerged among Tasmanian devils, rapidly decimating the population. We have recently discovered that DFTD cells lose the expression MHC molecules on the cell surface, explaining how this tumor avoids recognition by host CD8+T cells.
authors.affiliation: University of Cambridge; Department of Pathology; Cambridge, UK.
authors.forename: Hannah V
authors.initials: HV
authors.lastname: Siddle
authors.forename: Jim
authors.initials: J
authors.lastname: Kaufman
keywords: CTVT; DFTD; MHC; Tasmanian devil; conservation; contagious cancer; epigenetics; extinction; interferon; transmissible tumor