title: Paracrine mechanisms of proliferative, anti-apoptotic and anti-inflammatory effects of mesenchymal stromal cells in models of acute organ injury.
abstract: The purpose of this review is to systematize data from many studies and observations of proliferative, anti-apoptotic and anti-inflammatory effects of mesenchymal stromal cell (MSC) paracrine factors and their biologic effects in models of acute organ injury.
authors.affiliation: Sklifosovsky Research Institute for Emergency Medicine, Moscow, Russia.
authors.forename: Mogeli S
authors.initials: MS
authors.lastname: Khubutiya
authors.affiliation: Sklifosovsky Research Institute for Emergency Medicine, Moscow, Russia. Electronic address: vagab13@mail.ru.
authors.forename: Aleksandr V
authors.initials: AV
authors.lastname: Vagabov
authors.affiliation: Sklifosovsky Research Institute for Emergency Medicine, Moscow, Russia.
authors.forename: Andrey A
authors.initials: AA
authors.lastname: Temnov
authors.affiliation: Institute of Cell Biophysics, Puschino, Russia.
authors.forename: Alla N
authors.initials: AN
authors.lastname: Sklifas
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology; D049109:Cell Proliferation; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000502:physiology*; D019899:Paracrine Communication / Q000502:physiology
keywords: cytokines; growth factors; mesenchymal stromal cell-derived conditioned medium; mesenchymal stromal cells; paracrine factors