title: To B or not to B--that is the question for myocardial infarction.
abstract: After myocardial infarction (MI), circulating B cells produce the chemokine Ccl7, which mobilizes inflammatory monocytes from the bone marrow into the blood, after which they are then recruited to the injured heart, a new study shows. B cell depletion after MI limits myocardial injury and improves heart function, suggesting a new approach for the management of acute MI (pages 1273–1280).
authors.affiliation: Center for Immunology & Inflammatory Diseases, Division of Rheumatology, Allergy & Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Nancy D
authors.initials: ND
authors.lastname: Kim
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Luster
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000502:physiology*; D006321:Heart / Q000503:physiopathology*; D006801:Humans; D009000:Monocytes / Q000502:physiology*; D009203:Myocardial Infarction / Q000503:physiopathology*