title: Leiomyosarcoma.
abstract: This article presents an overview of the current literature about the biology, pathology, and the clinical management of leiomyosarcoma. In addition, the article emphasizes and discusses the current systemic treatment options available for patients with leiomyosarcoma, which range from cytotoxic chemotherapy to target therapies. Particular leiomyosarcoma subtypes, such as uterine leiomyosarcoma and inferior vena cava leiomyosarcoma, are discussed separately.
authors.affiliation: Fletcher Laboratory, Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Thorn 528, Boston, MA 02115, USA; Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
authors.forename: César
authors.initials: C
authors.lastname: Serrano
authors.forename: Suzanne
authors.initials: S
authors.lastname: George
mesh_terms: D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*
keywords: Chemotherapy; Leiomyosarcoma; Prognostic factors; Targeted therapy; Uterine leiomyosarcoma