title: SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs).
abstract: New technologies enabling genome-wide interrogation have led to a large and rapidly growing number of autism spectrum disorder (ASD) candidate genes. Although encouraging, the volume and complexity of these data make it challenging for scientists, particularly non-geneticists, to comprehensively evaluate available evidence for individual genes. Described here is the Gene Scoring module within SFARI Gene 2.0 (https://gene.sfari.org/autdb/GS_Home.do), a platform developed to enable systematic community driven assessment of genetic evidence for individual genes with regard to ASD.
authors.affiliation: Departments of Genetics and Neuroscience, Albert Einstein College of Medicine, Bronx, NY, USA.
authors.forename: Brett S
authors.initials: BS
authors.lastname: Abrahams
authors.affiliation: McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Dan E
authors.initials: DE
authors.lastname: Arking
authors.affiliation: Zilkha Neurogenetic Institute and Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Campbell
authors.affiliation: Department of Pediatrics, Division of Genetic Medicine, University of Washington, Seattle, WA, USA.
authors.forename: Heather C
authors.initials: HC
authors.lastname: Mefford
authors.affiliation: Department of Molecular Biology, Cell Biology and Biochemistry; and Department of Psychiatry and Human Behavior, Brown University, Providence, RI, USA.
authors.forename: Eric M
authors.initials: EM
authors.lastname: Morrow
authors.affiliation: IMHRO/Staglin Assistant Professor, Department of Psychiatry, Institute for Human Genetics, Center for Neurobiology and Psychiatry, UCSF, San Francisco, CA, USA.
authors.forename: Lauren A
authors.initials: LA
authors.lastname: Weiss
authors.affiliation: MindSpec Inc., 8280 Greensboro Drive, Suite 150, McLean, VA, USA.|Department of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
authors.forename: Idan
authors.initials: I
authors.lastname: Menashe
authors.affiliation: MindSpec Inc., 8280 Greensboro Drive, Suite 150, McLean, VA, USA.
authors.forename: Tim
authors.initials: T
authors.lastname: Wadkins
authors.affiliation: MindSpec Inc., 8280 Greensboro Drive, Suite 150, McLean, VA, USA.
authors.forename: Sharmila
authors.initials: S
authors.lastname: Banerjee-Basu
authors.affiliation: Simons Foundation Autism Research Initiative, New York, NY, USA.
authors.forename: Alan
authors.initials: A
authors.lastname: Packer