title: Multiagent chemotherapy for metastatic adenocarcinoma of the seminal vesicle.
abstract: Adenocarcinoma of the seminal vesicle is a rare condition, with fewer than 60 cases described in the literature. Most reports highlight the histopathological characteristics of the tumor; however, the role of chemotherapy, especially in the metastatic setting, is poorly described. In this paper, we describe a patient with metastatic disease, who sustained a response to modified FOLFOX6 as first-line therapy. This platinum-based combination therapy seems effective in this scenario and may provide an opportunity for extended survival and relief of symptoms.
authors.affiliation: Department of Radiology and Oncology, Cancer Institute of the State of São Paulo, Medical School of the University of São Paulo, São Paulo, Brazil.
authors.forename: Rodrigo S C
authors.initials: RS
authors.lastname: Guindalini
authors.forename: Milena P
authors.initials: MP
authors.lastname: Mak
authors.forename: Tiago K
authors.initials: TK
authors.lastname: Takahashi
authors.forename: Laura
authors.initials: L
authors.lastname: Testa
authors.forename: Carlos
authors.initials: C
authors.lastname: Dzik
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005472:Fluorouracil / Q000627:therapeutic use; D005834:Genital Neoplasms, Male / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008297:Male; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D010166:Palliative Care; D010984:Platinum / Q000008:administration & dosage / Q000627:therapeutic use; D012669:Seminal Vesicles / Q000473:pathology*
chemical_list: D009944:Organoplatinum Compounds; D010984:Platinum; D002955:Leucovorin; D005472:Fluorouracil