title: A real-time spectral mapper as an emerging diagnostic technology in biomedical sciences.
abstract: Real time spectral imaging and mapping at video rates can have tremendous impact not only on diagnostic sciences but also on fundamental physiological problems. We report the first real-time spectral mapper based on the combination of snap-shot spectral imaging and spectral estimation algorithms. Performance evaluation revealed that six band imaging combined with the Wiener algorithm provided high estimation accuracy, with error levels lying within the experimental noise. High accuracy is accompanied with much faster, by 3 orders of magnitude, spectral mapping, as compared with scanning spectral systems. This new technology is intended to enable spectral mapping at nearly video rates in all kinds of dynamic bio-optical effects as well as in applications where the target-probe relative position is randomly and fast changing.
authors.forename: George
authors.initials: G
authors.lastname: Epitropou
authors.forename: Vassilis
authors.initials: V
authors.lastname: Kavvadias
authors.forename: Dimitris
authors.initials: D
authors.lastname: Iliou
authors.forename: Efstathios
authors.initials: E
authors.lastname: Stathopoulos
authors.forename: Costas
authors.initials: C
authors.lastname: Balas
mesh_terms: D000465:Algorithms; D020811:Biomedical Technology / Q000295:instrumentation*; D001943:Breast Neoplasms / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000473:pathology; D003116:Color; D003199:Computer Systems; D003952:Diagnostic Imaging / Q000295:instrumentation*; D005260:Female; D006416:Hematoxylin / Q000737:chemistry; D006801:Humans
chemical_list: D006416:Hematoxylin