title: [Hypothermia risk factors in the very low weight newborn and associated morbidity and mortality in a neonatal care unit].
abstract: BACKGROUND
  Heat loss in the newborn after delivery could interfere with post-natal adaptation due to metabolic and hemodynamic instability. Associated perinatal factors and their relationship with morbidity and mortality during the neonatal period have not been systematically studied in our unit.
  
  
  OBJECTIVE
  To determine the temperature of very low birth weight (VLBW) infants on admission to our NICU, and to determine the associated perinatal variables, and the association of temperature with morbidity and mortality.
  
  
  METHODS
  Infants born in our maternity from January 2006 to November 2012, with birth weights (BW) 401 g to 1,499 g and/or less than 30 weeks gestational age, were included. A multivariate analysis was performed using the perinatal variables and the temperature on admission, as well as a logistic regression between these and the morbidity-mortality variables, in order to detect any independent associations.
  
  
  RESULTS
  A total of 635 infants were included, with a mean (± SD) birth weight and gestational age of 1,137.6 ± 257.6g, and 29.5 ± 2.0 weeks, respectively. The mean admission temperature was 35.8 ± 0.6°C (range: 33.0-37.8°C). The proportion of infants with a temperature < 36°C was 44.4%. Independently associated perinatal variables were chorioamnionitis, birth weight, vaginal delivery, and advanced cardiopulmonary resuscitation (CPR). Admission hypothermia was associated with severe intraventricular haemorrhage (IVH) (grades 3 and 4) (OR: 0.377; 95% CI: 0.221-0.643; P<.001), and mortality (OR: 0.329; 95% CI: 0.208-0.519; P=.012).
  
  
  CONCLUSIONS
  Hypothermia on admission is frequent among our VLBW infants. Birth weight, vaginal delivery, and advanced CPR were the principal variables associated with hypothermia. A low temperature on admission was related to an increased risk of IVH and mortality.
authors.affiliation: Servicio de Neonatología, Hospital Universitario Materno-Infantil de Las Palmas, Las Palmas de Gran Canaria, España. Electronic address: fgarciamu@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: García-Muñoz Rodrigo
authors.affiliation: Servicio de Neonatología, Hospital Universitario Materno-Infantil de Las Palmas, Las Palmas de Gran Canaria, España.
authors.forename: S
authors.initials: S
authors.lastname: Rivero Rodríguez
authors.affiliation: Servicio de Neonatología, Hospital Universitario Materno-Infantil de Las Palmas, Las Palmas de Gran Canaria, España.
authors.forename: C
authors.initials: C
authors.lastname: Siles Quesada
mesh_terms: D005260:Female; D006801:Humans; D007035:Hypothermia / Q000150:complications* / Q000453:epidemiology* / Q000401:mortality; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D007363:Intensive Care Units, Neonatal; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors
keywords: Hemorragia intraventricular; Hospital morbidity and mortality; Hypothermia on admission; Mortalidad; Prematuridad; Reanimación neonatal; Recién nacido de muy bajo peso; Risk factors; Temperatura; Very low birth weight infants