title: Anti-parietal cell antibodies and pernicious anemia in patients with type 1 diabetes mellitus and multiethnic background.
abstract: Anti-parietal cell (APC) antibodies and pernicious anemia (PA) were evaluated in patients with type 1 diabetes (n=75) and in controls. A higher frequency of APC (13.3%) and PA (4%) was found in cases than in controls (p=0.003), associated with other autoimmune diseases (p=0.003), but not with insulin or PTPN22 polymorphisms.
authors.affiliation: Federal University of Rio de Janeiro, Clementino Fraga Filho Universitary Hospital, Diabetes and Nutrology Department, Brazil.
authors.forename: Alinna Lage Ferraz
authors.initials: AL
authors.lastname: Pinto
authors.forename: Joana Rodrigues
authors.initials: JR
authors.lastname: Dantas
authors.forename: Debora
authors.initials: D
authors.lastname: Araujo
authors.forename: Bianca
authors.initials: B
authors.lastname: Barone
authors.forename: José Ângelo
authors.initials: JÂ
authors.lastname: de Souza Papi
authors.forename: José Egídio Paulo
authors.initials: JE
authors.lastname: de Oliveira
authors.forename: Lenita
authors.initials: L
authors.lastname: Zajdenverg
authors.forename: Melanie
authors.initials: M
authors.lastname: Rodacki
mesh_terms: D000293:Adolescent; D000328:Adult; D000752:Anemia, Pernicious / Q000097:blood / Q000150:complications*; D001323:Autoantibodies / Q000097:blood*; D016022:Case-Control Studies; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications*; D005006:Ethnicity; D005260:Female; D006801:Humans; D007328:Insulin / Q000235:genetics; D008297:Male; D010295:Parietal Cells, Gastric / Q000276:immunology*; D054596:Protein Tyrosine Phosphatase, Non-Receptor Type 22 / Q000235:genetics; D055815:Young Adult
chemical_list: D001323:Autoantibodies; D007328:Insulin; C516765:PTPN22 protein, human; D054596:Protein Tyrosine Phosphatase, Non-Receptor Type 22
keywords: Pernicious anemia; Type 1 diabetes