title: The feasibility study on 3-dimensional fluorescent x-ray computed tomography using the pinhole effect for biomedical applications.
abstract: We propose a 3-dimensional fluorescent x-ray computed tomography (CT) pinhole collimator, aimed at providing molecular imaging with quantifiable measures and sub-millimeter spatial resolution. In this study, we demonstrate the feasibility of this concept and investigate imaging properties such as spatial resolution, contrast resolution and quantifiable measures, by imaging physical phantoms using a preliminary imaging system developed with monochromatic synchrotron x rays constructed at the BLNE-7A experimental line at KEK, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Sunaguchi
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yuasa
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Hyodo
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Zeniya
mesh_terms: D005240:Feasibility Studies; D006801:Humans; D021621:Imaging, Three-Dimensional; D019047:Phantoms, Imaging; D011857:Radiographic Image Interpretation, Computer-Assisted; D014057:Tomography, X-Ray Computed / Q000379:methods*