title: High-order sliding-mode control for anesthesia.
abstract: Depth of anesthesia can be indirectly measured by Bispectral Index (BIS), therefore it is possible to administer propofol in a closed loop to maintain the optimal level of anesthesia while minimizing the dose to improve the postanesthesia recovery. High-Order Sliding-Mode control can be used to individualize drug dosing. In this study, the controller is tested with four in silico patients.
authors.forename: Ana
authors.initials: A
authors.lastname: Gallardo Hernández
authors.forename: Jonathan
authors.initials: J
authors.lastname: Eslava Escobar
authors.forename: Ron
authors.initials: R
authors.lastname: Leder
authors.forename: Ana Luisa
authors.initials: AL
authors.lastname: Hernández Pérez
authors.forename: Leonid
authors.initials: L
authors.lastname: Fridman
authors.forename: Jorge
authors.initials: J
authors.lastname: Dávila
authors.forename: Cristina
authors.initials: C
authors.lastname: Revilla Monsalve
authors.forename: Sergio
authors.initials: S
authors.lastname: Islas Andrade
mesh_terms: D000328:Adult; D000465:Algorithms; D000758:Anesthesia / Q000379:methods*; D003198:Computer Simulation; D056805:Consciousness Monitors; D005260:Female; D006801:Humans; D008875:Middle Aged; D015742:Propofol / Q000008:administration & dosage; D013514:Surgical Procedures, Operative
chemical_list: D015742:Propofol