title: Type III-B rotaxane dendrimers.
abstract: Type III-B first generation [3]rotaxane and second generation [4]rotaxane dendrimers have been synthesized via (1) a modified copper-catalyzed alkyne-azide cycloaddition (CuAAC), (2) Glaser-Hay's acetylenic oxidative homo-coupling, and (3) amide formation. The dendron does not reveal obvious cytotoxicities in L929 fibroblast cells. The rotaxane dendrimers can capture ammonia and are switchable both in solution and on surfaces.
authors.affiliation: Department of Chemistry, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, P. R. China.
authors.forename: Watson K-W
authors.initials: WK
authors.lastname: Ho
authors.forename: Siu-Fung
authors.initials: SF
authors.lastname: Lee
authors.forename: Chi-Hin
authors.initials: CH
authors.lastname: Wong
authors.forename: Xiao-Ming
authors.initials: XM
authors.lastname: Zhu
authors.forename: Chak-Shing
authors.initials: CS
authors.lastname: Kwan
authors.forename: Chun-Pong
authors.initials: CP
authors.lastname: Chak
authors.forename: Paula M
authors.initials: PM
authors.lastname: Mendes
authors.forename: Christopher H K
authors.initials: CH
authors.lastname: Cheng
authors.forename: Ken Cham-Fai
authors.initials: KC
authors.lastname: Leung
mesh_terms: D000818:Animals; D002460:Cell Line; D002470:Cell Survival; D003500:Cyclization; D050091:Dendrimers / Q000138:chemical synthesis* / Q000737:chemistry; D005347:Fibroblasts / Q000166:cytology; D051379:Mice; D015394:Molecular Structure; D043862:Rotaxanes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D050091:Dendrimers; D043862:Rotaxanes