title: [Successful treatment with prednisone in a critical ill newborn with symptomatic multifocal infantile hepatic hemangioendothelioma].
abstract: Infantile hepatic hemangioendothelioma is the most common vascular tumor of the liver in infancy. The diagnosis can be enunciated without histological defnition, if the clinical, analytical and images fndings are very suggestive; particularly in children less than six months old, because the biopsy is not exempt of complications. We report a female patient, four days old and 3500 g, who developed a hypovolemic shock as a complication of the biopsy from a multifocal infantile hepatic hemangioendothelioma. She developed clinical manifestations of cardiac failure and thrombocytopenia. Because of the critical clinical status we choose the medical treatment with prednisone which was administered for fve month and complete remission of the tumor was obtained. We highlight the Doppler ultrasonography as a safe and no invasive diagnosis method. Management of this disease is commented as well.
authors.affiliation: Servicio de Cirugía Hepatobiliar y Trasplante Hepático, Hospital Pediátrico William Soler, La Habana, Cuba.
authors.forename: Miurkis Endis
authors.initials: ME
authors.lastname: Miranda
authors.forename: Ramón
authors.initials: R
authors.lastname: Villamil Martínez
authors.forename: Pastor Alexander
authors.initials: PA
authors.lastname: Thomas Olivares
authors.forename: Juan Jose
authors.initials: JJ
authors.lastname: Trujillo Gálvez
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D016638:Critical Illness; D005260:Female; D006390:Hemangioendothelioma / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D008113:Liver Neoplasms / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use*; D012074:Remission Induction
chemical_list: D018931:Antineoplastic Agents, Hormonal; D011241:Prednisone