title: Activated platelet chemiluminescence and presence of CD45+ platelets in patients with acute myocardial infarction.
abstract: It has been found that in 15% of acute myocardial infarction patients' platelets generate reactive oxygen species that can be detected with luminol-enhanced chemiluminescence of platelet-rich plasma within 8-10 days after acute myocardial infarction. This increase in generate reactive oxygen species production coincides with the emergence of CD45(+) platelets. The ability of platelets to carry surface leukocyte antigen implies their participation in exchange of specific proteins in the course of acute myocardial infarction. Future studies of CD45(+) platelets in peripheral blood of acute myocardial infarction patients in association with generate reactive oxygen species production may provide a new insight into the complex mechanisms of cell-cell interactions associated with acute myocardial infarction.
authors.affiliation: Institute of Experimental Cardiology, Cardiology Research Center , Moscow , Russia .
authors.forename: Zufar
authors.initials: Z
authors.lastname: Gabbasov
authors.forename: Oxana
authors.initials: O
authors.lastname: Ivanova
authors.forename: Victor
authors.initials: V
authors.lastname: Kogan-Yasny
authors.forename: Evgeniya
authors.initials: E
authors.lastname: Ryzhkova
authors.forename: Olga
authors.initials: O
authors.lastname: Saburova
authors.forename: Inna
authors.initials: I
authors.lastname: Vorobyeva
authors.forename: Elena
authors.initials: E
authors.lastname: Vasilieva
mesh_terms: D001792:Blood Platelets / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D017493:Leukocyte Common Antigens / Q000097:blood*; D049449:Luminescence; D008297:Male; D009203:Myocardial Infarction / Q000097:blood* / Q000473:pathology; D015539:Platelet Activation; D017382:Reactive Oxygen Species / Q000097:blood*; D013997:Time Factors
chemical_list: D017382:Reactive Oxygen Species; D017493:Leukocyte Common Antigens
keywords: Acute myocardial infarction; CD45; chemiluminescence; platelets