title: The long time follow-up of craniovertebral junction fixation in patients with rheumatoid arthritis.
abstract: BACKGROUND
  Rheumatoid arthritis (RA) can have very destructive effects, especially in the cervical spine. Bone quality is poor in these patients. The purpose of this study is to evaluate the feasibility of fusion and accuracy of fluoroscopy in cervical transpedicular fixation (CPF) in a standardized clinical protocol for RA patients.
  
  
  METHODS
  96 pedicles of 15 patients operated between January 2000 and ay 2010 due to atlanto-axial and subaxial cervical subluxation were investigated for post-operative malposition of the transpedicular screws. Three-dimensional computed tomography was used as a useful tool in preoperative planning and in transarticular or transpedicular screw placement with the free hand technique in the cervical spine of RA patients. Fixation and reduction with fusion was performed in all of the patients, and autogrefts from iliac wing were used for fusion. Ranawat's and Nurick scales were used to assess the results. All screws were evaluated by Kast's criteria. Fusion or stability was evaluated on plain radiographs taken 3 weeks and 6, 12 and 60 months after the surgery.
  
  
  RESULTS
  Female to male ratio was 6/9. The mean age at the time of surgery was 57.4 years (range 44-72 years). Five of the patients were operated for both C1-2 and subaxial subluxation. Two of the 15 patients had only C1-2 subluxation and the remaining eight patients had only subaxial cervical subluxation. The screws were at their correct places in 84 pedicles (87.5.%) while minor breach was detected in 9 (10.9%). According to Ranawat's criteria, seven patients remained the same, and eight patients showed improvement. Instrumentation failure, loss of reduction or non-union was not observed at the final follow-up (average 31.5 months; range 24-60 months).
  
  
  CONCLUSIONS
  CPF provides a very strong three column stabilization and solid fusion in the osteoporotic vertebrae, but also carries a risk of vascular injury without nerve damage or in the RA patients, but the risk is low in experienced hands.
authors.affiliation: Department of Neurosurgery, TC Istanbul Arel University Tepekent, Istanbul, Turkey.
authors.forename: Kadir
authors.initials: K
authors.lastname: Kotil
keywords: Cervical pedicle; cervical posterior fixation; craniovertebral junction; follow-up; rheumatoid arthritis