title: Antioxidant activity of phenolics in leaves of three red pepper (Capsicum annuum) cultivars.
abstract: The antioxidant properties and phenolic profiles were first investigated in this paper on the leaves of three red pepper cultivars, Blackcuban (BCPL), Hongjinju (HPL), and Yeokgang-hongjanggun (YHPL). Of the ethanol extract of the three cultivars, BCPL showed potent antioxidant activities against the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and the 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical. Nine antioxidative compounds from the red pepper leaves were isolated and identified as one polyamine phenolic conjugate, N-caffeoylputrescine (1); three chlorogenic acid derivatives, 5-O-caffeoylquinic acid (2), 5-O-caffeoylquinic acid methyl ester (4), and 5-O-caffeoylquinic acid butyl ester (9); one anthocyanin, delphinidin-3-[4-trans-coumaroyl-l-rhamnosyl(1→6)glucopyranoside]-5-O-glucopyranoside (3); and four flavone glycosides, luteolin-7-O-apiofuranosyl(1→2)glucopyranoside (5), luteolin-7-O-glucopyranoside (6), apigenin 7-O-apiofuranosyl(1→2)glucopyranoside (7), apigenin-7-O-glucopyranoside (8). 1 and 3 had the greatest potential for radical-scavenging activity and HepG2 cells protecting effect against oxidative stress. BCPL exhibited the highest content of 1 and 3. Of the three cultivars BCPL may be considered a good source of antioxidants.
authors.affiliation: Functional Food Center, Korea Institute of Science and Technology (KIST) Gangneung Institute , Gangneung 210-340, Korea.
authors.forename: Woo-Ri
authors.initials: WR
authors.lastname: Kim
authors.forename: Eun Ok
authors.initials: EO
authors.lastname: Kim
authors.forename: Kyungsu
authors.initials: K
authors.lastname: Kang
authors.forename: Sarangerel
authors.initials: S
authors.lastname: Oidovsambuu
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Jung
authors.forename: Byung Sup
authors.initials: BS
authors.lastname: Kim
authors.forename: Chu Won
authors.initials: CW
authors.lastname: Nho
authors.forename: Byung-Hun
authors.initials: BH
authors.lastname: Um
mesh_terms: D000872:Anthocyanins / Q000302:isolation & purification / Q000494:pharmacology; D000975:Antioxidants / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology; D002212:Capsicum / Q000737:chemistry*; D056945:Hep G2 Cells; D006801:Humans; D018384:Oxidative Stress / Q000187:drug effects; D010636:Phenols / Q000032:analysis* / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry*; D013045:Species Specificity; D020122:tert-Butylhydroperoxide / Q000494:pharmacology
chemical_list: D000872:Anthocyanins; D000975:Antioxidants; D010636:Phenols; D010936:Plant Extracts; D020122:tert-Butylhydroperoxide