title: Influence of FBG sensors length on temperature measures in laser-irradiated pancreas: theoretical and experimental evaluation.
abstract: Temperature distribution T(x,y,z,t) in tissue undergoing Laser-induced Interstitial Thermotherapy (LITT) plays a crucial role on treatment outcome. Theoretical and experimental assessment of temperature on ex vivo laser-irradiated pancreas is presented. The aim of this work is to assess the influence of thermometers dimensions on temperature measures during LITT. T(x,y,z,t) inside tissue is monitored by optical sensors, i.e., Fiber Bragg Gratings (FBGs): three FBGs with lengths of 10 mm and nine FBGs of 1 mm, at different distances (2 mm, 5 mm and 10 mm) and different quotes (0 mm, 2 mm and 4 mm) from the laser fiber tip are used. Theoretical punctual T(x,y,z,t) is averaged out on both 10 mm and 1 mm in order to compare numerical predictions with experimental data. Results demonstrate the influence of FBG length on T(x,y,z,t) measures. This phenomenon depends on the distance between sensor and applicator: it is particularly significant close to the applicator tip (2 mm) because of the high spatial T(x,y,z,t) gradient within the tissue. Both theoretical results and experimental ones show that just at a distance of 10 mm from the tip, differences between T(x,y,z,t) provided by FBGs of 10 mm and 1 mm are negligible.
authors.forename: P
authors.initials: P
authors.lastname: Saccomandi
authors.forename: G
authors.initials: G
authors.lastname: Lupi
authors.forename: E
authors.initials: E
authors.lastname: Schena
authors.forename: A
authors.initials: A
authors.lastname: Polimadei
authors.forename: M
authors.initials: M
authors.lastname: Caponero
authors.forename: F
authors.initials: F
authors.lastname: Panzera
authors.forename: M
authors.initials: M
authors.lastname: Martino
authors.forename: F M
authors.initials: FM
authors.lastname: Di Matteo
authors.forename: S
authors.initials: S
authors.lastname: Sciuto
authors.forename: S
authors.initials: S
authors.lastname: Silvestri
mesh_terms: D000465:Algorithms; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation / Q000379:methods*; D007834:Lasers; D008962:Models, Theoretical; D010190:Pancreatic Neoplasms / Q000628:therapy; D013696:Temperature