title: Alleviation of weight-gain in mice by an ethanolic extract from Rubus coreanus under conditions of a high-fat diet and exercise.
abstract: The administration of an ethanolic extract (RCE) from Rubus coreanus significantly reduced the body weight and epididymal fat tissue of mice under conditions of a high-fat diet (HFD) and exercise. The mice also displayed enhanced muscular carnitine palmitoyltransferase 1 (CPT1) expression and increased superoxide dismutase and glutathione levels. These results suggest that RCE exerted an anti-obesity effect by up-regulating CPT1 and elevating the level of antioxidants.
authors.affiliation: Division of Food and Nutritional Science, Chonnam National University.
authors.forename: Changsik
authors.initials: C
authors.lastname: Chung
authors.forename: Yanghee
authors.initials: Y
authors.lastname: You
authors.forename: Ho-Geun
authors.initials: HG
authors.lastname: Yoon
authors.forename: Kyungmi
authors.initials: K
authors.lastname: Kim
authors.forename: Yoo-Hyun
authors.initials: YH
authors.lastname: Lee
authors.forename: Jeongmin
authors.initials: J
authors.lastname: Lee
authors.forename: Jin Woong
authors.initials: JW
authors.lastname: Chung
authors.forename: Hyunjung
authors.initials: H
authors.lastname: Chung
authors.forename: Soojin
authors.initials: S
authors.lastname: Yang
authors.forename: Woojin
authors.initials: W
authors.lastname: Jun
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology; D059305:Diet, High-Fat / Q000009:adverse effects*; D000431:Ethanol / Q000737:chemistry*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010805:Physical Conditioning, Animal; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology*; D027824:Rosaceae / Q000737:chemistry*; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D000975:Antioxidants; D010936:Plant Extracts; D000431:Ethanol