title: Blue two-photon fluorescence metal cluster probe precisely marking cell nuclei of two cell lines.
abstract: A bifunctional peptide was designed to in situ reduce Cu ions and anchor a Cu cluster. The peptide-Cu cluster probe, mainly composed of Cu14, emitted blue two-photon fluorescence under femtosecond laser excitation. Most important, the probe can specifically mark the nuclei of HeLa and A549 cells, respectively.
authors.affiliation: Lab for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, P. R. China. gaoxy@ihep.ac.cn.
authors.forename: Yaling
authors.initials: Y
authors.lastname: Wang
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Cui
authors.forename: Ru
authors.initials: R
authors.lastname: Liu
authors.forename: Yueteng
authors.initials: Y
authors.lastname: Wei
authors.forename: Xinglu
authors.initials: X
authors.lastname: Jiang
authors.forename: Huarui
authors.initials: H
authors.lastname: Zhu
authors.forename: Liang
authors.initials: L
authors.lastname: Gao
authors.forename: Yuliang
authors.initials: Y
authors.lastname: Zhao
authors.forename: Zhifang
authors.initials: Z
authors.lastname: Chai
authors.forename: Xueyun
authors.initials: X
authors.lastname: Gao
mesh_terms: D002460:Cell Line; D002467:Cell Nucleus / Q000502:physiology*; D003300:Copper / Q000737:chemistry*; D005453:Fluorescence; D006367:HeLa Cells; D006801:Humans; D009842:Oligopeptides / Q000138:chemical synthesis; D017785:Photons; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013056:Spectrophotometry, Ultraviolet
chemical_list: D009842:Oligopeptides; D003300:Copper