title: Desmoid tumors: a comprehensive review of the evolving biology, unpredictable behavior, and myriad of management options.
abstract: Desmoid tumors are rare, clonal collections of benign fibrous tissue that exhibit a highly variable clinical course. This article presents a comprehensive review of desmoid tumors and summarizes the current literature pertaining to clinical presentation, diagnostic modalities, pathogenesis, prognostic factors, and management options.
authors.affiliation: Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan, C407 Med Inn Building, 1500 East Medical Center Drive, SPC 5848, Ann Arbor, MI 48109-5848, USA.
authors.forename: Sumana
authors.initials: S
authors.lastname: Devata
authors.forename: Rashmi
authors.initials: R
authors.lastname: Chugh
mesh_terms: D018222:Desmoid Tumors / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D006801:Humans
keywords: Aggressive fibromatosis; Desmoid; Familial adenomatous polyposis; Review; Tyrosine kinase inhibitors