title: Aromatic peptide amphiphiles: significance of the Fmoc moiety.
abstract: Aromatic peptide amphiphile hydrogelators commonly utilise the fluorenyl-9-methoxycarbonyl moiety as an N-terminal capping group. Material properties and spectroscopic techniques show the influence of alternative linkers between the fluorenyl moiety and the peptide. This study establishes whether methoxycarbonyl is an optimal or mainly convenient linker, for this class of self-assembling systems.
authors.affiliation: WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow G1 1XL, UK. scott.fleming@strath.ac.uk rein.ulijn@strath.ac.uk.
authors.forename: Scott
authors.initials: S
authors.lastname: Fleming
authors.forename: Sisir
authors.initials: S
authors.lastname: Debnath
authors.forename: Pim W J M
authors.initials: PW
authors.lastname: Frederix
authors.forename: Tell
authors.initials: T
authors.lastname: Tuttle
authors.forename: Rein V
authors.initials: RV
authors.lastname: Ulijn
mesh_terms: D002942:Circular Dichroism; D005449:Fluorenes / Q000737:chemistry*; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry; D018625:Microscopy, Atomic Force; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013237:Stereoisomerism
chemical_list: C496789:9-fluorenylmethoxycarbonyl; D005449:Fluorenes; D010455:Peptides; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate