title: Membrane-based recovery of glucose from enzymatic hydrolysis of ionic liquid pretreated cellulose.
abstract: In this work, a membrane-based downstream process for the recovery of glucose from cellulose hydrolysis is described and evaluated. The cellulose is pretreated with the ionic liquid 1,3-dimethyl-imidazolium dimethylphosphate to reduce its crystallinity. After enzymatic conversion of cellulose to glucose the hydrolysate is filtered with an ultrafiltration membrane to remove residual particulates and enzymes. Nanofiltration is applied to purify the glucose from molecular intermediates, such as cellobiose originating from the hydrolysis reaction. Finally, the ionic liquid is removed from the hydrolysate via electrodialysis. Technically, these process steps are feasible. An economic analysis of the process reveals that the selling price of glucose from this production process is about 2.75 €/kg which is too high as compared to the current market price.
authors.affiliation: Aachener Verfahrenstechnik - Chemical Process Engineering, RWTH Aachen University, Turmstr. 46, 52064 Aachen, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Abels
authors.forename: Kristof
authors.initials: K
authors.lastname: Thimm
authors.forename: Helene
authors.initials: H
authors.lastname: Wulfhorst
authors.forename: Antje Christine
authors.initials: AC
authors.lastname: Spiess
authors.forename: Matthias
authors.initials: M
authors.lastname: Wessling
mesh_terms: D002475:Cellobiose / Q000302:isolation & purification; D002480:Cellulase / Q000378:metabolism*; D002482:Cellulose / Q000378:metabolism*; D003365:Costs and Cost Analysis; D055664:Electrochemical Techniques / Q000191:economics; D005947:Glucose / Q000191:economics / Q000302:isolation & purification*; D006868:Hydrolysis / Q000187:drug effects; D007475:Ion Exchange Resins; D052578:Ionic Liquids / Q000494:pharmacology*; D008567:Membranes, Artificial; D036103:Nanotechnology; D014462:Ultrafiltration
chemical_list: D007475:Ion Exchange Resins; D052578:Ionic Liquids; D008567:Membranes, Artificial; D002475:Cellobiose; D002482:Cellulose; D002480:Cellulase; D005947:Glucose
keywords: Cellulose; Electrodialysis; Enzymatic hydrolysis; Ionic liquid; Nanofiltration; Ultrafiltration