title: Fully automated calcium detection using optical coherence tomography.
abstract: Optical Coherence Tomography (OCT) is a new invasive technology for performing high-resolution cross-sectional imaging of the coronary arteries. In OCT images only Calcified plaque (CA) components can be accurately depicted as light penetrates hard tissue. In this work we present an automated method for detecting CA in OCT images. The method is fully automated as no user intervention is needed and includes three steps. In the first step the region between the lumen and the maximum penetration depth of OCT from the lumen border is determined. In the second step the region is classified into 3 clusters using the K-means algorithm. CA is identified using the results of k-means. The method was validated using experts' annotations on 27 images. The sensitivity of the method is 83% with Positive predictive value (PVV) 74 %.
authors.forename: Lambros S
authors.initials: LS
authors.lastname: Athanasiou
authors.forename: Christos V
authors.initials: CV
authors.lastname: Bourantas
authors.forename: George A
authors.initials: GA
authors.lastname: Rigas
authors.forename: Themis P
authors.initials: TP
authors.lastname: Exarchos
authors.forename: Antonis I
authors.initials: AI
authors.lastname: Sakellarios
authors.forename: Panagiotis K
authors.initials: PK
authors.lastname: Siogkas
authors.forename: Michail I
authors.initials: MI
authors.lastname: Papafaklis
authors.forename: Katerina K
authors.initials: KK
authors.lastname: Naka
authors.forename: Lampros K
authors.initials: LK
authors.lastname: Michalis
authors.forename: Francesco
authors.initials: F
authors.lastname: Prati
authors.forename: Dimitrios I
authors.initials: DI
authors.lastname: Fotiadis
mesh_terms: D000465:Algorithms; D002118:Calcium / Q000737:chemistry*; D016000:Cluster Analysis; D003331:Coronary Vessels / Q000473:pathology*; D003952:Diagnostic Imaging / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D010363:Pattern Recognition, Automated; D058226:Plaque, Atherosclerotic / Q000175:diagnosis; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods
chemical_list: D002118:Calcium