title: A retrospective analysis on the diagnostic value of ultrasound-guided percutaneous biopsy for peritoneal lesions.
abstract: BACKGROUND
  Routine examinations have a low specificity and a low positive rate for the diagnosis of peritoneal lesions. This study aimed to evaluate the diagnostic value and safety of ultrasound-guided percutaneous peritoneal lesion biopsies in patients with ascites and/or abdominal distension with unclear causes.
  
  
  METHODS
  A retrospective analysis was performed in 153 consecutive patients with ascites and/or abdominal distension with unclear causes. All of the patients showed abnormalities of the peritoneum or greater omentum after ultrasonography, and underwent ultrasound-guided percutaneous biopsies using a Bard auto-biopsy gun with 18- or 16-gauge biopsy needles.
  
  
  RESULTS
  The success rate of the procedures was 100% (153/153) and the satisfaction rate of the tissue specimens in the biopsy was 91.5% (140/153). A specific histopathological diagnosis was made in 142 out of 153 patients, with an overall diagnostic accuracy of 92.8%. Among the diagnosed patients, 62 were peritoneal metastatic adenocarcinoma, 49 were peritoneal tuberculosis, 11 were peritoneal malignant mesothelioma, 8 were chronic peritoneal infections, 7 were pseudomyxoma peritonei, and 5 were primary peritoneal lymphoma. Only 11 patients did not get a pathologic diagnosis due to the lack of sufficient tissue specimen. No serious complications occurred.
  
  
  CONCLUSIONS
  Ultrasound-guided percutaneous biopsy could be a simple, safe and accurate diagnostic method in patients with ascites and/or abdominal distension with unclear causes.
authors.affiliation: State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an 710032, China. wangjianhong@medmail.com.cn.
authors.forename: Jianhong
authors.initials: J
authors.lastname: Wang
authors.forename: Liucun
authors.initials: L
authors.lastname: Gao
authors.forename: Shanhong
authors.initials: S
authors.lastname: Tang
authors.forename: Tao
authors.initials: T
authors.lastname: Li
authors.forename: Yiming
authors.initials: Y
authors.lastname: Lei
authors.forename: Huahong
authors.initials: H
authors.lastname: Xie
authors.forename: Jie
authors.initials: J
authors.lastname: Liang
authors.forename: Baojun
authors.initials: B
authors.lastname: Chen
authors.forename: Xian
authors.initials: X
authors.lastname: Wang
authors.forename: Daiming
authors.initials: D
authors.lastname: Fan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001201:Ascites / Q000000981:diagnostic imaging / Q000601:surgery; D001706:Biopsy; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009852:Omentum / Q000000981:diagnostic imaging / Q000601:surgery; D010534:Peritoneal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies; D018084:Ultrasonography, Interventional; D055815:Young Adult