title: Fast grating-based X-ray phase-contrast tomosynthesis.
abstract: As an imaging technique with low radiation dose and improved contrast, digital x-ray tomosynthesis is widely used in clinical diagnoses. Based on the superior capability of x-ray phase-contrast imaging (PCI) techniques for imaging low density materials, the combination of X-ray tomosynthesis and PCI can potentially provide higher efficiency in the detection of soft tissues. The goal of this work was to develop a fast imaging method for phase-contrast tomosynthesis, called fast grating-based phase-contrast tomosynthesis (GPC-Tomo), which integrates tomosynthesis with a grating-based PCI technique. Following the interlaced phase-stepping (PS) data collection method, which is much faster than conventional PS method, we propose a novel image reconstruction method called inner-focusing (IF) reconstruction for the fast GPC-Tomo. The proposed IF reconstruction method was validated by real experiments and the results suggested its effectiveness in achieving a fast GPC-Tomo.
authors.forename: Yan
authors.initials: Y
authors.lastname: Xi
authors.forename: Jun
authors.initials: J
authors.lastname: Zhao
mesh_terms: D000818:Animals; D006801:Humans; D021621:Imaging, Three-Dimensional; D008810:Mice, Inbred C57BL; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement / Q000379:methods*