title: Acute lymphoblastic leukemia in pregnancy: a case report with literature review.
abstract: The management of acute lymphoblastic leukemia (ALL) during pregnancy requires treatment with high-dose chemotherapy that can pose risks to both the mother and fetus. Special consideration to chemotherapy regimen and its doses and to fetal gestational age at the time of chemotherapy administration should be taken in order to limit fetal exposure while still providing optimal therapy to the mother. Here we describe a 22-year-old patient who was diagnosed at 26 weeks gestation with ALL and was treated in the third trimester with HyperCVAD (cytoxan, vincristine, adriamycin, dexamethasone) combination chemotherapy giving birth via Caesarean section to a healthy baby girl 4 weeks after induction chemotherapy.
authors.affiliation: Department of Hematology/Oncology, MD Anderson Cancer Center Orlando, 1400 South Orange Avenue, Orlando, FL 32801, USA.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Ticku
authors.forename: Shilpa
authors.initials: S
authors.lastname: Oberoi
authors.forename: Sarah
authors.initials: S
authors.lastname: Friend
authors.forename: John
authors.initials: J
authors.lastname: Busowski
authors.forename: Mary
authors.initials: M
authors.lastname: Langenstroer
authors.forename: Said
authors.initials: S
authors.lastname: Baidas
keywords: Leukemia; pregnancy