title: New clinical application of high-intensity focused ultrasound: local control of synovial sarcoma.
abstract: High-intensity focused ultrasound (HIFU) is playing an increasingly important role in cancer therapy. Primary synovial sarcomas of the chest wall are extremely rare. We report the first case of noninvasive HIFU therapy for the control of synovial sarcoma. A 51-year-old man was diagnosed with spindle cell sarcoma on the left chest wall through lumpectomy. After four cycles of chemotherapy, local recurrence of the sarcoma was detected. Subsequent extended resection confirmed synovial sarcoma. After five cycles of a new chemotherapy option, the sarcoma relapsed again. Then the patient received five courses of HIFU; this completely ablated the sarcoma without complications. No chemotherapy, radiotherapy, or biological therapy has been applied since. Now the patient is stable and has a high quality of life.
authors.affiliation: Department of Surgical Oncology, Second Affiliated Hospital, Zhejiang University College of Medicine, No, 88 Jiefang Road, Hangzhou, PR China. dengyc001@hotmail.com.
authors.forename: Xiaoye
authors.initials: X
authors.lastname: Hu
authors.forename: Hongke
authors.initials: H
authors.lastname: Cai
authors.forename: Meiqi
authors.initials: M
authors.lastname: Zhou
authors.forename: Haifei
authors.initials: H
authors.lastname: He
authors.forename: Wei
authors.initials: W
authors.lastname: Tian
authors.forename: Yue
authors.initials: Y
authors.lastname: Hu
authors.forename: Lirong
authors.initials: L
authors.lastname: Chen
authors.forename: Yongchuan
authors.initials: Y
authors.lastname: Deng
mesh_terms: D057086:High-Intensity Focused Ultrasound Ablation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D011379:Prognosis; D013584:Sarcoma, Synovial / Q000628:therapy*; D013899:Thoracic Neoplasms / Q000628:therapy*