title: Visualization of pulsatile CSF motion separated by membrane-like structure based on four-dimensional phase-contrast (4D-PC) velocity mapping.
abstract: This work was performed to indicate the usefulness of magnetic resonance (MR) 4-dimentional phase contrast (4D-PC) technique in assessing CerebroSpinal Fluid (CSF) motion in comparison with the time-Spatial Labeling Inversion Pulse (Time-SLIP) technique. 4D-velocity vector, their curl, and, pressure gradient were evaluated in both flow phantom, and normal volunteers and a patient with hydrocepharus. The velocity and pressure gradient fields obtained by the 4D-PC technique were useful to visualize the CSF dynamics under the presence of a membrane-like structure, unlike the Time-SLIP in which the spin travel was visualized. Quantitative property was another advantage of the 4D-PC. The curl and the pressure gradient fields obtained with actual units should help clinicians to classify the conditions of the patients with CSF disorders.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yatsushiro
authors.forename: Akihiro
authors.initials: A
authors.lastname: Hirayama
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Matsumae
authors.forename: Kagayaki
authors.initials: K
authors.lastname: Kuroda
mesh_terms: D000328:Adult; D000465:Algorithms; D016080:Arachnoid Cysts / Q000473:pathology; D002555:Cerebrospinal Fluid; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000134:cerebrospinal fluid / Q000473:pathology; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008567:Membranes, Artificial; D008858:Microscopy, Phase-Contrast; D008875:Middle Aged; D019047:Phantoms, Imaging; D011312:Pressure; D011673:Pulsatile Flow; D055815:Young Adult
chemical_list: D008567:Membranes, Artificial