title: Entropy-based complexity of the cardiovascular control in Parkinson disease: comparison between binning and k-nearest-neighbor approaches.
abstract: Entropy-based approaches are frequently used to quantify complexity of short-term cardiovascular control from spontaneous beat-to-beat variability of heart period (HP) and systolic arterial pressure (SAP). Among these tools the ones optimizing a critical parameter such as the pattern length are receiving more and more attention. This study compares two entropy-based techniques for the quantification of complexity making use of completely different strategies to optimize the pattern length. Comparison was carried out over HP and SAP variability series recorded from 12 Parkinson's disease (PD) patients without orthostatic hypotension or symptoms of orthostatic intolerance and 12 age-matched healthy control (HC) subjects. Regardless of the method, complexity of cardiovascular control increased in PD group, thus suggesting the early impairment of cardiovascular function.
authors.forename: Alberto
authors.initials: A
authors.lastname: Porta
authors.forename: Vlasta
authors.initials: V
authors.lastname: Bari
authors.forename: Tito
authors.initials: T
authors.lastname: Bassani
authors.forename: Andrea
authors.initials: A
authors.lastname: Marchi
authors.forename: Stefano
authors.initials: S
authors.lastname: Tassin
authors.forename: Margherita
authors.initials: M
authors.lastname: Canesi
authors.forename: Franca
authors.initials: F
authors.lastname: Barbic
authors.forename: Raffaello
authors.initials: R
authors.lastname: Furlan
mesh_terms: D000368:Aged; D000465:Algorithms; D001794:Blood Pressure / Q000502:physiology; D002319:Cardiovascular System / Q000503:physiopathology*; D019277:Entropy; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology*; D013599:Systole / Q000502:physiology