title: Orthotopic heart transplantation in two infants with histiocytoid cardiomyopathy and left ventricular non-compaction.
abstract: HC is a rare cause of congestive heart failure that typically presents with malignant ventricular arrhythmias in infants, often requiring urgent intervention. Successful heart transplantation in a patient with HC has only been reported once (J Heart Lung Transplant 2004: 23: 902). The combination of HC with concurrent LVNC has only been described three times (Int J Legal Med 2009: 123: 47; Hum Pathol 2005: 36: 403; Pediatr Dev Pathol 2012: 15: 397). We report two rare cases of HC with LVNC in two infants presenting with cardiogenic shock, one requiring ECMO support who was successfully bridged to orthotopic heart transplantation with a Berlin Heart LVAD.
authors.affiliation: Division of Pediatric Cardiology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, USA.
authors.forename: Stephanie L
authors.initials: SL
authors.lastname: Siehr
authors.forename: Daniel
authors.initials: D
authors.lastname: Bernstein
authors.forename: Justin
authors.initials: J
authors.lastname: Yeh
authors.forename: Gerald J
authors.initials: GJ
authors.lastname: Berry
authors.forename: David N
authors.initials: DN
authors.lastname: Rosenthal
authors.forename: Seth A
authors.initials: SA
authors.lastname: Hollander
mesh_terms: D009202:Cardiomyopathies / Q000151:congenital* / Q000628:therapy; D002311:Cardiomyopathy, Dilated / Q000628:therapy; D014450:Electron Transport Complex III / Q000172:deficiency*; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006321:Heart / Q000503:physiopathology; D006333:Heart Failure / Q000628:therapy; D016027:Heart Transplantation / Q000379:methods*; D006352:Heart Ventricles / Q000503:physiopathology*; D006353:Heart-Assist Devices; D006801:Humans; D007223:Infant; D008297:Male; D012770:Shock, Cardiogenic / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D014450:Electron Transport Complex III
keywords: cardiomyopathy; histiocytoid; pediatric transplantation