title: Computed tomographic characteristics of odontogenic neoplasms in dogs.
abstract: Odontogenic neoplasms are locally invasive oral tumors in dogs. The purpose of this retrospective study was to describe CT characteristics for varying histopathologic types of canine odontogenic neoplasms. A board-certified veterinary radiologist who was unaware of histologic findings reviewed and scored imaging studies. A total of 29 dogs were included in the study. Twenty-three of these dogs had concurrent dental radiographs. The most common CT characteristics for all tumor types were a direct association with or in the region of multiple teeth in 96.4% (27/28), contrast enhancement in 96.3% (26/27), alveolar bone lysis in 93.1% (27/29), and mass-associated tooth displacement in 85.2% (23/27). Mass-associated cyst-like structures were identified in 53.6% (15/28) and were only present in tumors containing odontogenic epithelium. Canine acanthomatous ameloblastomas (n = 15) appeared as extra-osseous (10/15) or intra-osseous (5/15) masses. Intra-osseous canine acanthomatous ameloblastomas were more likely to have mass-associated cyst-like structures and were subjectively more aggressive when compared with extra-osseous canine acanthomatous ameloblastomas. Amyloid-producing odontogenic tumors (n = 3) had subjectively uniform CT imaging characteristics and consisted of round soft tissue and mineral attenuating masses with multiple associated cyst-like structures. Fibromatous epulides of periodontal ligament origin (n = 4) were contrast enhancing extra-osseous masses that were rarely referred for CT examinations and 25% (1/4) were not visible with CT. Other odontogenic tumors were less represented or had more variable CT imaging characteristics. Mass-associated tooth destruction was appreciated more often with dental radiographs and extra-oral tumor extension was identified more often with CT.
authors.affiliation: Radiology Section, Department of Clinical Studies, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, 19104.
authors.forename: Joseph T
authors.initials: JT
authors.lastname: Amory
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Reetz
authors.forename: Melissa D
authors.initials: MD
authors.lastname: Sánchez
authors.forename: Charles W
authors.initials: CW
authors.lastname: Bradley
authors.forename: John R
authors.initials: JR
authors.lastname: Lewis
authors.forename: Alexander M
authors.initials: AM
authors.lastname: Reiter
authors.forename: Wilfried
authors.initials: W
authors.lastname: Mai
mesh_terms: D000564:Ameloblastoma / Q000145:classification / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary; D000818:Animals; D004283:Dog Diseases / Q000145:classification / Q000000981:diagnostic imaging* / Q000473:pathology; D004285:Dogs; D005260:Female; D007573:Jaw Neoplasms / Q000145:classification / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D008297:Male; D009808:Odontogenic Tumors / Q000145:classification / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000662:veterinary
keywords: ameloblastoma; amyloid-producing; epulis; neoplasia; odontogenic; odontoma