title: [Oxygen supply to the brain in chronic disturbances of cerebral circulation in patients with pathology of brachiocephalic arteries].
abstract: We assessed objective parameters of cerebral oxygen supply in 469 patients with multifocal atherosclerosis, hemodynamically significant lesions in brachiocephalic arteries in dependence on degree of severity of vascular cerebral insufficiency according to A.V. Pokrovsky classification of chronic disturbances of cerebral circulation. Comparison of clinical classification with parameters of cerebral oximetry and level of cerebral tolerance to hypoxia allowed to characterize pathophysiological mechanisms of cerebral oxygen metabolism, what was important for determination of risk of surgical treatment and postoperative prognosis.
authors.affiliation: Academian E.N. Meshalkin Novosibirsk State Research Institute of Circulation Pathology, ul. Rechkunovskaya, 15, 630055 Novosibirsk, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Kamenskaia
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Loginova
authors.forename: A A
authors.initials: AA
authors.lastname: Karpenko
authors.forename: A M
authors.initials: AM
authors.lastname: Karas'kov
authors.forename: R A
authors.initials: RA
authors.lastname: Kuzhuget
mesh_terms: D000368:Aged; D050197:Atherosclerosis / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D001921:Brain / Q000098:blood supply / Q000378:metabolism; D002545:Brain Ischemia / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D002560:Cerebrovascular Circulation; D002908:Chronic Disease; D016894:Endarterectomy, Carotid / Q000379:methods; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography / Q000379:methods; D010101:Oxygen Consumption; D011379:Prognosis; D012720:Severity of Illness Index; D019265:Spectroscopy, Near-Infrared / Q000379:methods