title: Oxidative 1,2-difunctionalization of activated alkenes with benzylic C(sp3)-H bonds and aryl C(sp2)-H bonds.
abstract: DTBP (di-tert-butyl peroxide) is utilized to mediate oxidative 1,2-difunctionalization of activated alkenes with an aryl C(sp(2))-H bond and a benzylic C(sp(3))-H bond for the synthesis of functionalized oxindoles. This reaction is a new organomediated strategy for alkene difunctionalization facilitated by Lewis acids.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. jhli@hnu.edu.cn.
authors.forename: Ming-Bo
authors.initials: MB
authors.lastname: Zhou
authors.forename: Cheng-Yong
authors.initials: CY
authors.lastname: Wang
authors.forename: Ren-Jie
authors.initials: RJ
authors.lastname: Song
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
authors.forename: Wen-Ting
authors.initials: WT
authors.lastname: Wei
authors.forename: Jin-Heng
authors.initials: JH
authors.lastname: Li
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D003510:Cyclohexanes / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D000078183:Oxindoles
chemical_list: D000475:Alkenes; D003510:Cyclohexanes; D007211:Indoles; D000078183:Oxindoles; C022960:2-oxindole; C067220:di-tert-butylperoxy-3,3,5-trimethylcyclohexane peroxide