title: Stereocontrolled first total syntheses of amarouciaxanthin A and B.
abstract: The first total syntheses of amarouciaxanthin A and B (C40) via the stereoselective Wittig reaction of C15-allenic and C15-acetylenic tri-n-butylphosphonium salts with the unprecedented C25-3,8-dihydroxy-5,6-epoxyapocarotenal have been completed. Oxidation of the two hydroxyl groups in the left part of the resulting condensation products followed by regioselective oxirane ring opening gave the target carotenoids.
authors.affiliation: Department of Organic Chemistry for Life Science, Kobe Pharmaceutical University , 4-19-1, Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan.
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Yamano
authors.forename: Mahankhali Venu
authors.initials: MV
authors.lastname: Chary
authors.forename: Akimori
authors.initials: A
authors.lastname: Wada
mesh_terms: D008968:Molecular Conformation; D013237:Stereoisomerism; D024341:Xanthophylls / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D024341:Xanthophylls; C046849:amarouciaxanthin A; C046850:amarouciaxanthin B