title: rac-Methyl (3aR*,4S*,5R*,7aR*)-5,7a-bis-(acet-yloxy)-3-oxo-2-phenyl-octa-hydro-1H-iso-indole-4-carboxyl-ate.
abstract: The title molecule, C20H23NO7, the product of nucleophilic cleavage of the 3a,6-ep-oxy bridge in 1-oxo-2-phenyl-octa-hydro-3a,6-ep-oxy-iso-indole-7-carboxyl-ate, comprises a cis-fused bicyclic system containing a 2-pyrrolidinone ring in an envelope conformation (with the C atom bearing the carboxyl-ate substituent as the flap) and a cyclo-hexane ring in a chair conformation. The carboxyl-ate substituent occupies the equatorial position, whereas the two acet-yloxy substituents are in axial positions. The N atom has a trigonal-planar geometry, the sum of the bond angles being 359.3 (3)°. The dihedral angle between the mean plane of the four planar atoms of the pyrrolidinone ring and the phenyl ring is 25.98 (6)°. In the crystal, mol-ecules are linked into zigzag chains along the c-axis direction by C-H⋯O hydrogen bonds.
authors.affiliation: Department of Chemistry, University of Douala, Faculty of Sciences, PO Box 24157, Douala, Republic of , Cameroon.
authors.forename: Flavien A A
authors.initials: FA
authors.lastname: Toze
authors.forename: Eugeniya V
authors.initials: EV
authors.lastname: Nikitina
authors.forename: Vladimir P
authors.initials: VP
authors.lastname: Zaytsev
authors.forename: Fedor I
authors.initials: FI
authors.lastname: Zubkov
authors.forename: Victor N
authors.initials: VN
authors.lastname: Khrustalev