title: The first genetically confirmed case of Dioctophyme renale (Nematoda: Dioctophymatida) in a patient with a subcutaneous nodule.
abstract: We describe a nematode larva in a subcutaneous nodule excised from a 44-year-old Chinese male who had been living in Japan for 15 years. Morphological features suggested that the worm was a dioctophimatid nematode. PCR amplification and sequencing of small subunit ribosomal DNA and mitochondrial cytochrome subunit c oxidase genes allowed us to identify the larva as the giant kidney worm, Dioctophyme renale (Goeze, 1972). This is the first molecularly confirmed human case of a dermal D. renale infection.
authors.affiliation: Section of Environmental Parasitology, Graduate School of Medicine and Dentistry Science, Tokyo Medical and Dental University, 1-5-45 Yushima, Tokyo 113-8519, Japan.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Tokiwa
authors.forename: Wataru
authors.initials: W
authors.lastname: Ueda
authors.forename: Satoshi
authors.initials: S
authors.lastname: Takatsuka
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Okawa
authors.forename: Masayuki
authors.initials: M
authors.lastname: Onodera
authors.forename: Nobuo
authors.initials: N
authors.lastname: Ohta
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Akao
mesh_terms: D000038:Abscess / Q000469:parasitology / Q000473:pathology; D000328:Adult; D000818:Animals; D001483:Base Sequence; D018509:DNA, Helminth / Q000235:genetics; D006099:Granuloma / Q000469:parasitology / Q000473:pathology; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D009348:Nematoda / Q000145:classification* / Q000235:genetics; D009349:Nematode Infections / Q000469:parasitology* / Q000473:pathology; D010802:Phylogeny
chemical_list: D018509:DNA, Helminth
keywords: Adenophorea; Dermal infection; Dioctophymatid nematode; Dioctophyme renale; Larva migrans; Molecular diagnosis