title: Carney complex with biatrial cardiac myxoma.
abstract: Cardiac myxomas make up approximately 50% of all benign cardiac tumors and represented 86% of all surgically treated cardiac tumors. Most of them originated from the left atrium, in some cases from both of atria. We report a case of male patient with biatrial myxomas and other extra-cardiac involvement: hypophyseal adenoma, enlargement of thyroid gland, tubular adenoma polyp of colon and bilateral large cell calcifying Sertoli cell tumor (LCCSCT) of testis. These findings led to the diagnosis of Carney's complex, which is a syndrome with multiple neoplasias, cardiac myxomas, lentigines, and endocrine abnormalities. A genetic test confirm this diagnosis.
authors.affiliation: Department of Anaesthesiology and Intensive Care, National Institute of Cardiovascular Disease, Bratislava, Slovakia.
authors.forename: Eniko
authors.initials: E
authors.lastname: Havrankova
authors.forename: Emoke
authors.initials: E
authors.lastname: Stenova
authors.forename: Ingrid
authors.initials: I
authors.lastname: Olejarova
authors.forename: Katarina
authors.initials: K
authors.lastname: Sollarova
authors.forename: Sona
authors.initials: S
authors.lastname: Kinova
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000235:genetics; D001706:Biopsy; D006348:Cardiac Surgical Procedures; D056733:Carney Complex / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D054756:Cyclic AMP-Dependent Protein Kinase RIalpha Subunit / Q000235:genetics; D004252:DNA Mutational Analysis; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006325:Heart Atria / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D009154:Mutation; D009232:Myxoma / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D011237:Predictive Value of Tests; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D014408:Biomarkers, Tumor; D054756:Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; C517834:PRKAR1A protein, human