title: Sensitivity, specificity, and reproducibility of the Capilia TB-Neo assay.
abstract: The performance of the Capilia TB-Neo assay, a new-generation assay, was assessed by determining its sensitivity, specificity, reproducibility, and cross-reaction with contaminating organisms. The sensitivity and specificity were 99.2 and 96.4% and 89.3 and 100% in pure and mixed-culture isolates, respectively. The kappa statistic was 95.0 and 77.9% in pure and mixed culture isolates, respectively. There was no cross-reaction with contaminating organisms.
authors.affiliation: Zambia AIDS-Related Tuberculosis Project, University of Zambia School of Medicine, Department of Medicine, Lusaka, Zambia.
authors.forename: Monde
authors.initials: M
authors.lastname: Muyoyeta
authors.forename: Winnie C
authors.initials: WC
authors.lastname: Mwanza
authors.forename: Nkatya
authors.initials: N
authors.lastname: Kasese
authors.forename: Maina
authors.initials: M
authors.lastname: Cheeba-Lengwe
authors.forename: Maureen
authors.initials: M
authors.lastname: Moyo
authors.forename: Deborah
authors.initials: D
authors.lastname: Kaluba-Milimo
authors.forename: Helen
authors.initials: H
authors.lastname: Ayles
mesh_terms: D003429:Cross Reactions; D003955:Diagnostic Tests, Routine / Q000379:methods*; D006801:Humans; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000175:diagnosis*