title: An epidemiological study of Hypoderma infection and control using ivermectin in yaks in Qinghai Province, China.
abstract: The prevalence of Hypoderma spp. in yaks grazed in the east of Qinghai province was investigated in 2008. In this area, the prevalence in young yaks (1- to 3-year-old) was very high at 82.2-98.7%, whilst in adult yaks (4-year-old and older), the prevalence was 42.4-50.6%. The seasonal development and migration pattern of Hypoderma larvae in yak bodies was found to be similar for different locations in this area. The numbers of first, second and third instar larvae detected in yak bodies peaked in October, December and March, respectively. Different doses of ivermectin (125 to 500 µg/kg body weight) almost completely dewormed the larvae from yaks, suggesting that using a quarter of the prescribed dose (500 µg/kg body weight) was effective. In October of each year between 2009 and 2012, ivermectin (125 µg/kg body weight) was administered to a total of 562,995 yaks grazed in four counties in Qinghai province, and the pevalence of Hypoderma larval infection in yaks was reduced to 0.5-1.0%.
authors.affiliation: Academy of Animal and Veterinary Medicine, University of Qinghai, No. 1, Weier road, Sci-biological Industry Areas, Xining, Qinghai, The People of Republic of China.
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Yong
authors.initials: Y
authors.lastname: Fu
authors.forename: Hong
authors.initials: H
authors.lastname: Duo
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Guo
authors.forename: Xiuying
authors.initials: X
authors.lastname: Shen
authors.forename: Fuqiang
authors.initials: F
authors.lastname: Huang
authors.forename: Kai
authors.initials: K
authors.lastname: Feng
authors.forename: Zhisheng
authors.initials: Z
authors.lastname: Dang
authors.forename: Peng
authors.initials: P
authors.lastname: Mao
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Nasu
authors.forename: Nariaki
authors.initials: N
authors.lastname: Nonaka
mesh_terms: D000367:Age Factors; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology* / Q000469:parasitology* / Q000517:prevention & control*; D002681:China / Q000453:epidemiology; D004175:Diptera / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D007306:Insecticides / Q000494:pharmacology*; D007559:Ivermectin / Q000494:pharmacology; D009198:Myiasis / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary*; D015995:Prevalence; D012621:Seasons
chemical_list: D007306:Insecticides; D007559:Ivermectin