title: [Surgical treatment for left-sided heart valve disease in a national reference hospital in Lima, Peru].
abstract: OBJECTIVE
  To describe the preoperative, intraoperative and postoperative characteristics of patients with left-sided heart valve disease treated in the thoracic and cardiovascular surgery service of a national reference hospital; as well as to describe the occurrence of thromboembolic and bleeding events in these patients.
  
  
  METHODS
  A retrospective longitudinal study was carried out, which included 185 patients who underwert surgery between 1999 and 2006 at the Hospital Nacional Dos de Mayo (Lima, Peru). The patients were divided into 4 groups: patients with mitral commissurotomy; with aortic valve replacement; with mitral valve replacement and with double valve replacement. T-student test, Chi-square test, analysis of variance and Bonferroni test were used. The survival analysis took into account the severe thromboembolic and bleeding events and a follow-up period of 7 years was set.
  
  
  RESULTS
  The average durations of disease was 4.6 years. The most frequent etiology was rheumatic valve disease (74.6%). Hospital mortality was 3.8%, the most frequent cause of death was low cardiac output syndrome associated to multiple organ failure. The incidence of ischemic events (thrombosis or embolization) in patients who had a long-term valve replacement (more than 6 months) was 3.2%, and the incidence of bleeding events was 4.3%.
  
  
  CONCLUSIONS
  The results of surgical treatment for left-sided heart valve disease in Peru are favorable. The rate of complications and hospital mortality rate, as well as the long-term thromboembolic and bleeding events are comparable to those reported in the world literature.
authors.affiliation: Portneuf Medical Center, Idaho, EE. UU.
authors.forename: Julio C
authors.initials: JC
authors.lastname: Vasquez
authors.forename: Ciro A
authors.initials: CA
authors.lastname: Barrantes
authors.forename: Julio E
authors.initials: JE
authors.lastname: Peralta
authors.forename: Luis E
authors.initials: LE
authors.lastname: Rojas
mesh_terms: D000293:Adolescent; D000328:Adult; D006348:Cardiac Surgical Procedures / Q000379:methods; D002648:Child; D005260:Female; D006349:Heart Valve Diseases / Q000601:surgery*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010568:Peru; D011183:Postoperative Complications / Q000453:epidemiology*; D019106:Postoperative Hemorrhage / Q000453:epidemiology*; D012017:Referral and Consultation; D012189:Retrospective Studies; D013923:Thromboembolism / Q000453:epidemiology*; D055815:Young Adult