title: Applicability of scanning laser ophthalmoscopy microperimetry on the fixation patterns of monofixation syndrome.
abstract: OBJECTIVE
  To investigate the monocular fixation pattern and characteristics in patients with monofixation syndrome using scanning laser ophthalmoscopy (SLO) microperimetry (MP).
  
  
  METHODS
  Twenty-four patients older than 5 years who had 8 prism diopters (PD) or less of deviation after surgery were analyzed. The A group included 14 patients with infantile esotropia (ET), and 10 patients with acquired ET were assigned to B group. The monocular fixation pattern and characteristics of all patients were investigated using SLO MP. Central or mild eccentric fixation was defined as eyes with more than 50% of the fixation points located within the 2° diameter circle centred on the fovea.
  
  
  RESULTS
  Mean ages at the time of surgery were 27 (range, 11-48) months in A group and 75 (range, 27-166) months in B group. Mean ages at the time of MP examination were 117 (range, 64-210) months in A group and 106 (range, 64-167) months in B group. Mean distant and near angles of esodeviation were -1.7 PD (-8 to 8) and -2.7 PD (-8 to 6) in A group and 0.6 PD (-2 to 8) and -0.4 PD (-2 to 0) in B group. Central or mild eccentric fixation was present in 8 patients (57%) and moderate or severe eccentric fixation in 6 patients (43%) in A group. In contrast, all patients in B group had central or mild eccentric fixation (p = 0.022).
  
  
  CONCLUSIONS
  Postoperative moderate eccentric or severe eccentric fixations were observed in 43% of patients with infantile ET in either eye; however, all patients with acquired ET showed central or mild eccentric fixation in both eyes.
authors.affiliation: Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Youngsub
authors.initials: Y
authors.lastname: Eom
authors.forename: Seung-Hyun
authors.initials: SH
authors.lastname: Kim
authors.forename: Seong-Woo
authors.initials: SW
authors.lastname: Kim
authors.forename: Yoonae A
authors.initials: YA
authors.lastname: Cho
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004948:Esotropia / Q000601:surgery; D005260:Female; D005403:Fixation, Ocular / Q000502:physiology*; D006801:Humans; D007223:Infant; D008297:Male; D015835:Ocular Motility Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D009801:Oculomotor Muscles / Q000601:surgery; D013508:Ophthalmologic Surgical Procedures / Q000009:adverse effects; D009887:Ophthalmoscopy / Q000379:methods*; D011183:Postoperative Complications; D012160:Retina / Q000503:physiopathology*; D012607:Scotoma / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D013577:Syndrome; D058609:Visual Field Tests / Q000379:methods*