title: Comparative study of valved and nonvalved fully implantable catheters inserted via ultrasound-guided puncture for chemotherapy.
abstract: BACKGROUND
  Fully implantable catheters are important for oncology treatments. They can be functionally categorized as valved or nonvalved. Theoretically, a valve prevents spontaneous blood reflux into the catheter, reducing the incidence of complications. We sought to compare the results from the implantation of valved and nonvalved fully implantable 8-French catheters inserted via ultrasound-guided puncture in cancer patients undergoing chemotherapy treatment.
  
  
  METHODS
  A retrospective analysis of 100 patients who underwent long-term catheter implantation guided by ultrasound was performed looking for early (≤30 days) or late (≥90 days) complications. They were evaluated regarding the use of valved or nonvalved catheter and assessed on univariate model.
  
  
  RESULTS
  The only early complication (hematoma) was identified in the valved group. Twenty-two late complications were identified (72.72% in the valved group and 27.27% in the nonvalved group; P = 0.009). Blood reflux dysfunction, which occurred in 12 patients in the valved and none in the nonvalved devices group, was the only complication with an incidence that was significantly different between the groups.
  
  
  CONCLUSIONS
  Fully implantable valved catheters with Groshong (Bard Medical Division, Covington, GA) valves have a higher rate of blood reflux dysfunction compared with nonvalved catheters, but this did not interfere with the efficacy of the treatment.
authors.affiliation: Hospital A.C. Camargo Cancer Center, São Paulo, Brazil. Electronic address: guilherme.bomfim@accamargo.org.br.
authors.forename: Guilherme A
authors.initials: GA
authors.lastname: Zottele Bomfim
authors.affiliation: Hospital A.C. Camargo Cancer Center, São Paulo, Brazil.
authors.forename: Nelson
authors.initials: N
authors.lastname: Wolosker
authors.affiliation: Hospital A.C. Camargo Cancer Center, São Paulo, Brazil.
authors.forename: Guilherme
authors.initials: G
authors.lastname: Yazbek
authors.affiliation: Hospital A.C. Camargo Cancer Center, São Paulo, Brazil.
authors.forename: Christiano V
authors.initials: CV
authors.lastname: Bernardi
authors.affiliation: Hospital A.C. Camargo Cancer Center, São Paulo, Brazil.
authors.forename: Luisa A
authors.initials: LA
authors.lastname: Valentim
authors.affiliation: Hospital A.C. Camargo Cancer Center, São Paulo, Brazil.
authors.forename: Thiago M
authors.initials: TM
authors.lastname: De Castro
authors.affiliation: Hospital A.C. Camargo Cancer Center, São Paulo, Brazil.
authors.forename: Bruno S
authors.initials: BS
authors.lastname: Pignataro
authors.affiliation: Hospital A.C. Camargo Cancer Center, São Paulo, Brazil.
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Benitti
authors.affiliation: Hospital A.C. Camargo Cancer Center, São Paulo, Brazil.
authors.forename: Kenji
authors.initials: K
authors.lastname: Nishinari
mesh_terms: D061605:Administration, Intravenous; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002405:Catheterization, Central Venous / Q000009:adverse effects / Q000295:instrumentation*; D002408:Catheters, Indwelling; D004867:Equipment Design; D005260:Female; D006406:Hematoma / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011677:Punctures; D012189:Retrospective Studies; D013997:Time Factors; D018084:Ultrasonography, Interventional; D062666:Vascular Access Devices; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents