title: Asymmetric N-heterocyclic carbene (NHC)-catalyzed annulation of modified enals with enolizable aldehydes.
abstract: N-Heterocyclic carbene (NHC)-catalyzed highly enantioselective lactonization of modified enals with enolizable aldehydes, proceeding via the α,β-unsaturated acylazolium intermediates, is reported. The reaction results in the asymmetric synthesis of synthetically important 4,5-disubstituted dihydropyranones.
authors.affiliation: Organic Chemistry Division, and Center for Materials Characterization, CSIR-National Chemical Laboratory , Dr. Homi Bhabha Road, Pune - 411008, India.
authors.forename: Santhivardhana Reddy
authors.initials: SR
authors.lastname: Yetra
authors.forename: Trinadh
authors.initials: T
authors.lastname: Kaicharla
authors.forename: Sunita S
authors.initials: SS
authors.lastname: Kunte
authors.forename: Rajesh G
authors.initials: RG
authors.lastname: Gonnade
authors.forename: Akkattu T
authors.initials: AT
authors.lastname: Biju