title: Whole genome sequencing and phylogenetic analysis of West Nile virus lineage 1 and lineage 2 from human cases of infection, Italy, August 2013.
abstract: A human outbreak of West Nile virus (WNV) infection caused by WNV lineage 2 is ongoing in northern Italy. Analysis of six WNV genome sequences obtained from clinical specimens demonstrated similarities with strains circulating in central Europe and Greece and the presence of unique amino acid changes that identify a new viral strain. In addition, WNV lineage 1 Livenza, responsible for a large outbreak in north-eastern Italy in 2012, was fully sequenced from a blood donor during this 2013 outbreak.
authors.affiliation: Department of Molecular Medicine, University of Padova, Padova, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Barzon
authors.forename: M
authors.initials: M
authors.lastname: Pacenti
authors.forename: E
authors.initials: E
authors.lastname: Franchin
authors.forename: E
authors.initials: E
authors.lastname: Lavezzo
authors.forename: G
authors.initials: G
authors.lastname: Masi
authors.forename: L
authors.initials: L
authors.lastname: Squarzon
authors.forename: S
authors.initials: S
authors.lastname: Pagni
authors.forename: S
authors.initials: S
authors.lastname: Toppo
authors.forename: F
authors.initials: F
authors.lastname: Russo
authors.forename: M
authors.initials: M
authors.lastname: Cattai
authors.forename: R
authors.initials: R
authors.lastname: Cusinato
authors.forename: G
authors.initials: G
authors.lastname: Palu
mesh_terms: D001483:Base Sequence; D004196:Disease Outbreaks; D016678:Genome; D006801:Humans; D007558:Italy / Q000453:epidemiology; D017720:Molecular Epidemiology; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics*; D014901:West Nile Fever / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics* / Q000821:virology; D014902:West Nile virus / Q000145:classification* / Q000235:genetics*
chemical_list: D012367:RNA, Viral