title: Blood pressure elevation in hemodialysis patients after the Great East Japan Earthquake.
abstract: A major earthquake measuring 9.0 on the Richter scale struck northeastern Japan at 2:46 pm on 11 March 2011. Several reports have described transient increases in blood pressure after major earthquakes, but the impact of such increases on hemodialysis patients has not been reported. We retrospectively investigated changes in blood pressure and influencing factors in 205 patients (mean age 66.6±13.0 years; male 51.7%; median dialysis vintage 6.0 (2.0-11.0) years) on chronic dialysis at three dialysis centers in the affected area (Fukushima City) for 8 weeks after the earthquake. Pre-dialysis blood pressure was significantly elevated at 1 week after the earthquake compared with baseline (systolic vs. diastolic blood pressure: 153.1±20.2/80.1±13.5 vs. 148.6±20.0/77.5±12.8 mm Hg, P<0.001), similarly post-dialysis blood pressure was elevated for up to 8 weeks. Independent factors influencing changes in blood pressure after the earthquake comprised baseline blood pressure and α-blockers. The earthquake induced a significant elevation in blood pressure among patients on chronic dialysis, and activation of the sympathetic nervous system might at least in part be associated with the mechanism underlying this increase.
authors.affiliation: Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Tani
authors.affiliation: Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Nakayama
authors.affiliation: Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Tanaka
authors.affiliation: Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan.
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Hayashi
authors.affiliation: Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Asahi
authors.affiliation: Division of Urology, Fukushima Minami Junkankika Hospital, Fukushima, Japan.
authors.forename: Tatsuhiko
authors.initials: T
authors.lastname: Kamata
authors.affiliation: Ogihara Clinic, Fukushima, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Ogihara
authors.affiliation: Division of Nephrology, Fujita General Hospital, Fukushima, Japan.
authors.forename: Keiji
authors.initials: K
authors.lastname: Sato
authors.affiliation: Division of Clinical Epidemiology, Jikei University School of Medicine, Tokyo, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Matsushima
authors.affiliation: Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Watanabe
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure / Q000502:physiology*; D015897:Comorbidity; D004232:Diuretics / Q000627:therapeutic use; D055866:Earthquakes; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007564:Japan / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000503:physiopathology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012084:Renin-Angiotensin System / Q000187:drug effects
chemical_list: D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D004232:Diuretics