title: Solitary plasmacytoma of skull: a rare cytological diagnosis.
abstract: Solitary Plasmacytoma of the Skull (SPS) is very rare and only 35 cases have been reported in the English literature. It remains controversial whether a solitary plasmacytoma of the skull is essentially identical with a Solitary Plasmacytoma of Bone (SPB) or not. A solitary plasmacytoma of bone, which includes a solitary plasmacytoma of the skull, is characterized by a radiologically solitary bone lesion, neoplastic plasma cells in the biopsy specimen, fewer than 5% plasma cells in bone marrow, less than 2.0 g/dl monoclonal protein in the serum when it is present and a negative urine test for Bence Jones protein (monoclonal light chain). A solitary plasmacytoma of bone tends to disseminate or progress to multiple myeloma, even as long as 7-23 years after its presentation.
authors.affiliation: Senior Resident, Department of Pathology, SR in UCMS/GTBH , Delhi, India .
authors.forename: Manmeet Kaur
authors.initials: MK
authors.lastname: Gill
authors.forename: Manisha
authors.initials: M
authors.lastname: Makkar
authors.forename: Satinder Pal Singh
authors.initials: SP
authors.lastname: Bains
keywords: Fine needle aspiration cytology; Skull; Solitary plasmacytoma