title: Activation of platelets by the endocannabinoids 2-arachidonoylglycerol and virodhamine is mediated by their conversion to arachidonic acid and thromboxane A2, not by activation of cannabinoid receptors.
authors.affiliation: Institute for Prevention of Cardiovascular Diseases, Ludwig Maximilians University of Munich , Munich , Germany.
authors.forename: S Annette
authors.initials: SA
authors.lastname: Brantl
authors.forename: Anna L
authors.initials: AL
authors.lastname: Khandoga
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Siess
mesh_terms: D001095:Arachidonic Acids / Q000378:metabolism / Q000494:pharmacology; D001792:Blood Platelets / Q000378:metabolism*; D063386:Cannabinoid Receptor Agonists / Q000378:metabolism / Q000494:pharmacology*; D002186:Cannabinoids / Q000494:pharmacology*; D063388:Endocannabinoids / Q000378:metabolism / Q000494:pharmacology; D005989:Glycerides / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D015539:Platelet Activation / Q000187:drug effects*; D043882:Receptors, Cannabinoid / Q000378:metabolism; D013928:Thromboxane A2 / Q000378:metabolism*
chemical_list: D001095:Arachidonic Acids; D063386:Cannabinoid Receptor Agonists; D002186:Cannabinoids; D063388:Endocannabinoids; D005989:Glycerides; D043882:Receptors, Cannabinoid; C456739:virodhamine; D013928:Thromboxane A2; C094503:glyceryl 2-arachidonate