title: Prevention: Polypills for cardiovascular prevention: a step forward?
abstract: The effect of a fixed-dose combination drug strategy ('polypill') on patients' adherence to medication was analysed in a series of 2,004 individuals with, or at high risk of, cardiovascular disease in the UMPIRE study. The polypill improved adherence by >20%, but the reduction in blood-pressure and cholesterol levels was modest.
authors.affiliation: Centro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Alamgro 3, 28029 Madrid, Spain.
authors.forename: Ginés
authors.initials: G
authors.lastname: Sanz
authors.forename: Valentin
authors.initials: V
authors.lastname: Fuster
mesh_terms: D000924:Anticholesteremic Agents / Q000008:administration & dosage*; D000959:Antihypertensive Agents / Q000009:adverse effects*; D002318:Cardiovascular Diseases / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D016903:Drug Monitoring
chemical_list: D000924:Anticholesteremic Agents; D000959:Antihypertensive Agents; D010975:Platelet Aggregation Inhibitors