title: An update on liver surgery for cholangiocarcinoma.
abstract: Cholangiocarcinoma is a malignant neoplasm that originates from biliary epithelial cells. Complete tumor resection remains the most effective treatment of intra-hepatic or perihilar cholangiocarcinomas (PHCs). The objectives of this are to update and discuss methods that are likely to increase the resectability of cholangiocarcinomas, and to define the limits beyond which the risks of the treatments outweigh their benefits. We analyzed intra-hepatic cholangiocarcinomas and PHCs separately to determine the site of origin and the resectability of the tumor. We discussed the site at which to perform hepatic optimization prior to surgery, and whether liver transplantation might affect cholangiocarcinoma treatment.
authors.affiliation: Service de Chirurgie Hépatobiliaire et Digestive, Centre Hospitalier Universitaire de Rennes, Université de Rennes 1, Rennes Cedex, France, karim.boudjema@chu-rennes.fr.
authors.forename: Karim
authors.initials: K
authors.lastname: Boudjema
authors.forename: Giovanni Battista
authors.initials: GB
authors.lastname: Levi Sandri
authors.forename: Eveline
authors.initials: E
authors.lastname: Boucher
authors.forename: Tanguy
authors.initials: T
authors.lastname: Rohou
authors.forename: Michel
authors.initials: M
authors.lastname: Rayar
authors.forename: Laurent
authors.initials: L
authors.lastname: Sulpice
mesh_terms: D001650:Bile Duct Neoplasms / Q000601:surgery*; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000601:surgery*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000601:surgery*