title: Malignant soft tissue tumors in children.
abstract: Soft tissue masses are frequently seen in children. Although most are benign or reactive, soft tissue sarcomas (STS)-both rhabdomyosarcoma (most common) and non-rhabdo STS, do occur in the extremities. Appropriate evaluation of extremity soft tissue tumors often includes a biopsy as the clinical and imaging features may not be enough to establish a definitive diagnosis. Much needs to be done for improving the treatment of these rare but often devastating sarcomas. Given the small numbers of these cases seen at various centers, collaborative efforts should be made to further our understanding and improve the management of these challenging cases.
authors.affiliation: Department of Orthopedic Surgery, Nemours - Alfred I duPont Hospital for Children, 1600 Rockland Road, Wilmington, DE 19803, USA. Electronic address: mihir.thacker@nemours.org.
authors.forename: Mihir M
authors.initials: MM
authors.lastname: Thacker
mesh_terms: D001706:Biopsy; D002648:Child; D003582:Cytogenetics; D006801:Humans; D007150:Immunohistochemistry; D009367:Neoplasm Staging; D012509:Sarcoma / Q000175:diagnosis / Q000235:genetics / Q000628:therapy*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000628:therapy*
keywords: Extremity; Lump; Pediatric; Sarcoma; Soft tissue mass; Soft tissue tumor