title: Angiosarcomas and other sarcomas of endothelial origin.
abstract: Although benign hemangiomas are among the most common diagnoses among connective tissue tumors, angiosarcomas and other sarcomas arising from blood vessels are rare, even among sarcomas. Because endothelial tumors have unique embryonal derivation compared with other sarcomas, it is not surprising they have unique characteristics. Herein are reviewed some of these unique characteristics and therapeutic options for patients with some of these diagnoses, highlighting the potential of new agents for these tumors, which will in all likelihood also impact treatment on more common cancers.
authors.affiliation: Department of Medicine, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, Box 1128, New York, NY 10029-6574, USA; Department of Pediatrics, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, Box 1128, New York, NY 10029-6574, USA.
authors.forename: Angela
authors.initials: A
authors.lastname: Cioffi
authors.forename: Sonia
authors.initials: S
authors.lastname: Reichert
authors.forename: Cristina R
authors.initials: CR
authors.lastname: Antonescu
authors.forename: Robert G
authors.initials: RG
authors.lastname: Maki
mesh_terms: D006394:Hemangiosarcoma / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D006801:Humans
keywords: Angiosarcoma; Epithelioid hemangioendothelioma; FLT4; KDR; Kaposi sarcoma; Organ transplant; Translocation; VEGF; Vascular sarcoma