title: Retrospective review of pharyngeal gonorrhea treatment failures in Alberta, Canada.
abstract: Our review of Neisseria gonorrhoeae pharyngeal treatment failures from sexually transmitted infection clinics in Alberta suggests that treatment failures with oral cefixime monotherapy were not related to elevated cefixime minimum inhibitory concentrations. Dual therapy with oral cefixime and azithromycin may be a suitable alternate for the treatment of pharyngeal gonorrhea.
authors.affiliation: From the *STI Services, Alberta Health Services (AHS), Edmonton, Canada; †STI Clinic, AHS, Edmonton, Canada; ‡STI Clinic, AHS, Calgary, Canada; and §Provincial Laboratory for Public Health, AHS, Calgary, Canada.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Gratrix
authors.forename: Joshua
authors.initials: J
authors.lastname: Bergman
authors.forename: Cari
authors.initials: C
authors.lastname: Egan
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Drews
authors.forename: Ron
authors.initials: R
authors.lastname: Read
authors.forename: Ameeta E
authors.initials: AE
authors.lastname: Singh
mesh_terms: D000328:Adult; D000416:Alberta / Q000453:epidemiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use*; D020682:Cefixime / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000302:isolation & purification; D010608:Pharyngeal Diseases / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D010614:Pharynx / Q000382:microbiology* / Q000473:pathology; D012189:Retrospective Studies; D012725:Sexual Behavior / Q000706:statistics & numerical data; D017211:Treatment Failure
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin; D020682:Cefixime