title: Pain course in conservatively treated patients with back pain and a VCF on the spine radiograph (VERTOS III).
abstract: OBJECTIVE
  Little is known about the natural course of pain from vertebral compression fractures (VCF). In this study we evaluated the pain course in conservatively treated patients with back pain and a VCF on the spine radiograph.
  
  
  METHODS
  Between May 2007 and November 2008, 169 patients with back pain referred by the general practitioner for spine radiographs and with a VCF were requested to participate in this follow-up study. Base line questionnaires about visual analogue scale (VAS) score, type of treatment and use of osteoporosis medication were filled in by 82 patients. Questionnaires were repeated at 6 weeks, and at 3, 6 and 12 months. Significant pain relief was defined as a decrease in VAS score of 50% or more from baseline.
  
  
  RESULTS
  At baseline, mean VAS score in 82 patients was 6.9 (SD 2.0). Significant pain relief at 12 months was reported by 44 patients (54%) while in 38 patients (46%) pain relief was insufficient. No predictors for pain relief could be identified. Patients with insufficient pain relief at 12 months used significantly more analgesics and in these patients physiotherapy did better than other types of therapy.
  
  
  CONCLUSIONS
  More than half of conservatively treated patients with back pain and VCF had sufficient pain relief at 12 months with most pain decrease in the first 3 months. However, a substantial proportion of patients still reported disabling pain. There were no predictors for the development of chronic pain. Patients with continuing pain ≥3 months after diagnosis of VCF may be candidates for vertebroplasty.
authors.affiliation: Department of Radiology, St. Elisabeth Ziekenhuis, Hilvarenbeekseweg 60, 5022GC, Tilburg, The Netherlands, radiol@eztilburg.nl.
authors.forename: Alexander
authors.initials: A
authors.lastname: Venmans
authors.forename: P N M
authors.initials: PN
authors.lastname: Lohle
authors.forename: W J
authors.initials: WJ
authors.lastname: van Rooij
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001416:Back Pain / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D005260:Female; D050815:Fractures, Compression / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D010147:Pain Measurement; D011859:Radiography; D016103:Spinal Fractures / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome