title: Bloch simulations towards direct detection of oscillating magnetic fields using MRI with spin-lock sequence.
abstract: A new MRI method using the spin-lock sequence has attracted wide attention because of its potential for detecting small oscillating magnetic fields. However, as the mechanism involved is complicated, we visualized the magnetization performance during the spin-lock sequence in order to better understand interaction of the spin-lock pulse and the externally applied oscillating magnetic fields by means of a fast-and-simple method using matrix operations to solve a time-dependent Bloch equation. To improve spin-lock imaging in the detection of small magnetic fields (in an fMRI experiment that modeled neural magnetic fields), we observed that the phenomenon decreases MR signals, which led us to investigate how spin-lock parameters cause the MR signal to decrease; based on this, we determined that MR signals decrease in oscillating magnetic fields that are resonant with the spin-lock pulse. We also determined that MR signals decrease is directly proportional to spin-lock duration. Our results suggest that MRI can feasibly detect oscillating magnetic fields directly by using of the spin-lock sequence.
authors.forename: Shizue
authors.initials: S
authors.lastname: Nagahara
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Kobayashi
mesh_terms: D003198:Computer Simulation; D060526:Magnetic Fields; D008279:Magnetic Resonance Imaging; D012815:Signal Processing, Computer-Assisted; D013113:Spin Labels
chemical_list: D013113:Spin Labels