title: Low pulmonary function in individuals with impaired fasting glucose: the 2007-2009 Korea national health and nutrition examination survey.
abstract: OBJECTIVE
  To investigate the association between fasting plasma glucose level and pulmonary function.
  
  
  METHODS
  Nutritional information, pulmonary function data, and laboratory test data from 9,223 subjects from the fourth Korea National Health and Nutrition Examination Survey were examined. The participants were divided into five groups according to fasting plasma glucose (FPG) level: normal fasting glucose (NFG)1, FPG <90 mg/dl; NFG2, FPG 90-99 mg/dl; impaired fasting glucose (IFG)1: FPG 100-109 mg/dl; IFG2, FPG 110-125 mg/dl; and diabetes, FPG ≥126 mg/dl and/or current anti-diabetes medications.
  
  
  RESULTS
  After adjustment for several variables, the percentage of predicted forced vital capacity(FVC%) decreased with increasing fasting plasma glucose level in both sexes[men: (mean ± SEM) 92.0±0.3 in NFG1; 91.9±0.3 in NFG2; 92.0±0.4 in IFG1; 90.2±0.7 in IFG2; and 89.9±0.5 in diabetes, P = 0.004; women: 93.7±0.3 in NFG1; 93.7±0.3 in NFG2; 93.1±0.5 in IFG1; 91.1±0.9 in IFG2; and 90.7±0.6 in diabetes, P<0.001]. A logistic regression analysis found that IFG2 and diabetes were independently associated with the lowest quintile of predicted FVC% (IFG2: odds ratio [95%CI], 1.50 [1.18-1.89], P = 0.001; diabetes: 1.56 [1.30-1.88], P<0.001) using NFG1 as a control.
  
  
  CONCLUSIONS
  The current data suggest that forced vital capacity may begin to decrease in the higher range of IFG.
authors.affiliation: Department of Internal Medicine, Inje University College of Medicine, Busan, Korea.
authors.forename: Yun Jeong
authors.initials: YJ
authors.lastname: Lee
authors.forename: Na Kyung
authors.initials: NK
authors.lastname: Kim
authors.forename: Ju Yean
authors.initials: JY
authors.lastname: Yang
authors.forename: Jung Hyun
authors.initials: JH
authors.lastname: Noh
authors.forename: Sung-Soon
authors.initials: SS
authors.lastname: Lee
authors.forename: Kyung Soo
authors.initials: KS
authors.lastname: Ko
authors.forename: Byoung Doo
authors.initials: BD
authors.lastname: Rhee
authors.forename: Dong-Jun
authors.initials: DJ
authors.lastname: Kim
mesh_terms: D000704:Analysis of Variance; D001786:Blood Glucose / Q000032:analysis*; D005215:Fasting / Q000097:blood*; D005260:Female; D044882:Glucose Metabolism Disorders / Q000453:epidemiology* / Q000503:physiopathology; D006801:Humans; D016015:Logistic Models; D008297:Male; D009752:Nutritional Status / Q000502:physiology*; D016017:Odds Ratio; D056910:Republic of Korea / Q000453:epidemiology; D012129:Respiratory Function Tests; D013147:Spirometry; D014797:Vital Capacity / Q000502:physiology*
chemical_list: D001786:Blood Glucose