title: Management recommendations for invasive dental treatment in patients using oral antithrombotic medication, including novel oral anticoagulants.
abstract: OBJECTIVE
  The aims were (1) to search the scientific literature from 2007 to 2012 for guidelines and new studies on the dental management of patients using oral antithrombotic medication; (2) to summarize the articles' evidence and recommendations; and (3) to propose an updated clinical practice guideline for general dentists.
  
  
  METHODS
  A systematic literature search in MEDLINE, Embase, and the Guideline websites, from October 2007 to October 2012, produced articles that were critically evaluated.
  
  
  RESULTS
  The systematic literature search for guidelines yielded 74 citations (MEDLINE, 45; Embase, 22; and the Guideline websites, 7). Of these, only 2 guideline publications and 2 systematic reviews met the inclusion criteria. They yielded 32 recommendations.
  
  
  CONCLUSIONS
  The evidence and subsequent recommendations from published guidelines all point in the same direction: do not interrupt oral antithrombotic medication, not even dual antiplatelet therapy, in simple dental procedures.
authors.affiliation: Assistant Professor and Director of Medicine, Clinic for Medical-Dental Interaction, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, the Netherlands. Electronic address: d.v.diermen@acta.nl.
authors.forename: Denise E
authors.initials: DE
authors.lastname: van Diermen
authors.forename: Isaäc
authors.initials: I
authors.lastname: van der Waal
authors.forename: Johan
authors.initials: J
authors.lastname: Hoogstraten
mesh_terms: D000284:Administration, Oral; D000925:Anticoagulants / Q000008:administration & dosage*; D017742:Dental Care for Chronically Ill; D006801:Humans; D019647:Oral Surgical Procedures; D019106:Postoperative Hemorrhage / Q000517:prevention & control*; D017410:Practice Guidelines as Topic
chemical_list: D000925:Anticoagulants