title: Confronting inconsistencies in the amphibian-chytridiomycosis system: implications for disease management.
abstract: Chytridiomycosis, caused by the pathogenic fungus Batrachochytrium dendrobatidis (Bd), is one of the largest threats to wildlife and is putatively linked to the extirpation of numerous amphibians. Despite over a decade of research on Bd, conflicting results from a number of studies make it difficult to forecast where future epizootics will occur and how to manage this pathogen effectively. Here, we emphasize how resolving these conflicts will advance Bd management and amphibian conservation efforts. We synthesize current knowledge on whether Bd is novel or endemic, whether amphibians exhibit acquired resistance to Bd, the importance of host resistance versus tolerance to Bd, and how biotic (e.g. species richness) and abiotic factors (e.g. climate change) affect Bd abundance. Advances in our knowledge of amphibian-chytrid interactions might inform the management of fungal pathogens in general, which are becoming more common and problematic globally.
authors.affiliation: Department of Integrative Biology, University of South Florida, 4202 East Fowler Avenue, SCA 110, Tampa, FL, 33620, U.S.A.
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Venesky
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Raffel
authors.forename: Taegan A
authors.initials: TA
authors.lastname: McMahon
authors.forename: Jason R
authors.initials: JR
authors.lastname: Rohr
mesh_terms: D000663:Amphibians / Q000276:immunology / Q000382:microbiology*; D000818:Animals; D044822:Biodiversity; D008411:Chytridiomycota / Q000502:physiology*; D057231:Climate Change; D003247:Conservation of Natural Resources; D054884:Host-Pathogen Interactions; D009181:Mycoses / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*
keywords: Batrachochytrium dendrobatidis; alternative hosts; climate change; conservation; dilution effect; emerging infectious disease; fungal pathogen