title: Combined angiography for high-quality near-infrared autofluorescence images.
abstract: OBJECTIVE
  To describe an innovative imaging technique to obtain high-quality near-infrared autofluorescence (NIA) images.
  
  
  METHODS
  Simultaneous fluorescein angiography + indocyanine green angiography (FA + ICGA) acquisition mode (without dye injection) of Spectralis HRA + OCT (Heidelberg Retina Angiograph; Heidelberg Engineering, Heidelberg, Germany), setting maximum level of illuminance, and Automatic Real-time (ART) Module (Heidelberg Engineering) to increase signal-to-noise ratio.
  
  
  RESULTS
  The combined confocal scanning laser ophthalmoscope technique allows the Spectralis HRA + OCT device to create high-quality NIA ART images.
  
  
  CONCLUSIONS
  This innovative imaging technique, consisting of simultaneous FA + ICGA acquisition mode, setting maximum level of illuminance, and ART, allows the Spectralis HRA + OCT device to create high-quality NIA ART images, without requiring the need for the HRA2 (Heidelberg Retina Angiograph; Heidelberg Engineering) device.
authors.affiliation: *MD, PhD Department of Ophthalmology, University Paris Est Creteil, Centre Hospitalier Intercommunal de Creteil, Creteil, France (GQ, EHS); and Department of Ophthalmology, Hospital San Raffaele, University Vita Salute San Raffaele, Milan, Italy (GQ).
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Querques
authors.forename: Eric H
authors.initials: EH
authors.lastname: Souied
mesh_terms: D004396:Coloring Agents; D003952:Diagnostic Imaging / Q000379:methods*; D015352:Dry Eye Syndromes / Q000175:diagnosis; D005451:Fluorescein Angiography / Q000379:methods*; D006801:Humans; D007208:Indocyanine Green; D007259:Infrared Rays; D019721:Ophthalmoscopes
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green