title: Test-retest reliability of the infant car-seat challenge.
abstract: OBJECTIVE
  To evaluate how a single infant car-seat challenge (ICSC) predicts subsequent respiratory physiology in premature infants.
  
  
  METHODS
  Prospective observational study of infants born at <37 weeks gestational age. Subjects underwent three ICSCs and we evaluated clinical characteristics, pass rate, and predictive value of a single ICSC pass.
  
  
  RESULTS
  Completed three ICSCs on 60 subjects. Seven failed initial ICSC (11.7%). Those who failed had lower birth weights. Of the 53 that initially passed, 47 passed two subsequent tests (89%). Those who passed an initial test and failed a subsequent test had lower weights at each ICSC.
  
  
  CONCLUSIONS
  Our results indicate that passing an ICSC is highly predictive of passing subsequent ICSCs. Lower weights at birth and at the time of ICSC were associated with increased risk of failure. We recommend including low birth weight as an inclusion criterion for ICSCs.
authors.affiliation: Division of Neonatology, University of Maryland Hospital for Children, Baltimore, MD, USA.
authors.forename: N L
authors.initials: NL
authors.lastname: Davis
authors.affiliation: Division of Newborn Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
authors.forename: M L
authors.initials: ML
authors.lastname: Gregory
authors.affiliation: 1] Division of Respiratory Diseases, Boston Children's Hospital, Boston, MA, USA [2] Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA.
authors.forename: L
authors.initials: L
authors.lastname: Rhein
mesh_terms: D001049:Apnea / Q000209:etiology; D001835:Body Weight; D057207:Child Restraint Systems / Q000009:adverse effects*; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight; D007234:Infant, Premature / Q000502:physiology*; D011446:Prospective Studies; D015203:Reproducibility of Results; D012129:Respiratory Function Tests