title: Increase in prominence of electrocardiographic J waves after a single dose of propofol in a patient with early ventricular repolarisation.
abstract: J waves appear on an electrocardiogram as an elevation of the J point in the terminal portion of the QRS complex. J waves are often benign, but may be associated with malignant ventricular arrhythmias. In some cases, such problems appear to have been precipitated by propofol infusions. We observed a sudden increase in J waves and profound hypotension following a single intravenous dose of propofol in an 84-year-old woman with early repolarisation in the inferior ventricular wall. When early repolarisation (as shown by electrocardiographic J waves) is observed in the inferior ventricular wall pre-operatively, patients should be carefully monitored. Myocardial ischaemia and the use of drugs that might worsen J waves should be avoided.
authors.affiliation: Department of Dental Anaesthesiology, The University of Tokushima Graduate School, Tokushima, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Takaishi
authors.forename: S
authors.initials: S
authors.lastname: Kawahito
authors.forename: H
authors.initials: H
authors.lastname: Yamada
authors.forename: T
authors.initials: T
authors.lastname: Soeki
authors.forename: M
authors.initials: M
authors.lastname: Sata
authors.forename: H
authors.initials: H
authors.lastname: Kitahata
mesh_terms: D000369:Aged, 80 and over; D018686:Anesthetics, Intravenous / Q000009:adverse effects*; D004562:Electrocardiography / Q000187:drug effects; D005260:Female; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D007431:Intraoperative Complications / Q000139:chemically induced*; D016343:Monitoring, Intraoperative / Q000379:methods; D015742:Propofol / Q000009:adverse effects*; D014693:Ventricular Fibrillation / Q000139:chemically induced*
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol