title: Childhood Guillain-Barré syndrome subtypes in northern India.
abstract: This prospective cross-sectional study was conducted at a tertiary care research centre in North India to describe the frequency and clinical characteristics of subtypes of childhood Guillain-Barré syndrome. Among the 68 children enrolled, 65 were finally diagnosed with Guillain-Barré syndrome (median age, 60 months); 45 (69%) were boys. The most common subtype was acute motor axonal neuropathy in 27 patients (41.5%, 95% confidence interval [CI] 29-54), followed by acute inflammatory demyelinating polyneuropathy in 15 (23%, 95% CI 13.5-35), and acute motor sensory axonal neuropathy in three (4.6%, 95% CI 1-13). Twelve patients (18.5%, 95% CI 10-30) had inexcitable nerves, and eight (12.4%, 95% CI 5.5-23) were unclassifiable. Those with acute inflammatory demyelinating polyneuropathy were more likely to have had a preceding upper respiratory tract infection. The acute motor axonal neuropathy subtype peaked in incidence during the winter and monsoon months.
authors.affiliation: Neurology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Naveen
authors.initials: N
authors.lastname: Sankhyan
authors.affiliation: Department of Pediatrics, Lady Hardinge Medical College, New Delhi, India.
authors.forename: Suvasini
authors.initials: S
authors.lastname: Sharma
authors.affiliation: Rainbow Children's Hospital and Perinatal Centre, Hyderabad, India.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Konanki
authors.affiliation: Division of Pediatric Neurology, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar East, New Delhi, DL 110029, India. Electronic address: sheffaligulati@gmail.com.
authors.forename: Sheffali
authors.initials: S
authors.lastname: Gulati
mesh_terms: D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D020275:Guillain-Barre Syndrome / Q000145:classification* / Q000453:epidemiology*; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male
keywords: AIDP; AMAN; Acute polyneuropathy; Antiganglioside; GBS; Paralysis