title: Crystallographic characterization of a fully rotated, basic diiron dithiolate: model for the H(red) state?
abstract: A lucky break: A combination of steric pressure and electron asymmetry has provided the first example of a diiron dithiolate that is both rotated and basic. The present work establishes the feasibility of a hydride free rotated structure for the Hred state of the enzyme.
authors.affiliation: Department of Chemistry, University of Illinois, 600 S. Goodwin Ave., Urbana, IL 61801 (USA).
authors.forename: Wenguang
authors.initials: W
authors.lastname: Wang
authors.forename: Thomas B
authors.initials: TB
authors.lastname: Rauchfuss
authors.forename: Curtis E
authors.initials: CE
authors.lastname: Moore
authors.forename: Arnold L
authors.initials: AL
authors.lastname: Rheingold
authors.forename: Luca
authors.initials: L
authors.lastname: De Gioia
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Zampella
mesh_terms: D020134:Catalytic Domain; D018360:Crystallography, X-Ray; D006864:Hydrogenase / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D008024:Ligands; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D008024:Ligands; D013438:Sulfhydryl Compounds; D007501:Iron; D006864:Hydrogenase
keywords: active site; co-ligands; hydrides; hydrogenase; iron