title: [Neoadjuvant, adjuvant and palliative chemotherapy of penile cancer].
abstract: Data on the treatment of advanced penile carcinoma especially for chemotherapy are very limited. Due to the results of recent studies there has been a shift to taxan/cisplatinum based regimens. Initial case reports also showed a response to targeted therapy especially antibodies against epidermal growth factor receptor (EGFR). Nevertheless, a curative treatment by medicinal approaches alone does not appear to be possible for metastatic penile cancer and can be only cured by multimodal approaches, including neoadjuvant and adjuvant chemotherapy and salvage lymph node dissection. Palliative chemotherapy of advanced penile cancer has to be individually adapted and weighed against best supportive care for the final decision.
authors.affiliation: Klinik und Poliklinik für Urologie, Universitätsmedizin Rostock, E. Heydemannstraße 6, 18055, Rostock, Deutschland, chris.protzel@med.uni-rostock.de.
authors.forename: C
authors.initials: C
authors.lastname: Protzel
authors.forename: A K
authors.initials: AK
authors.lastname: Seitz
authors.forename: O W
authors.initials: OW
authors.lastname: Hakenberg
authors.forename: M
authors.initials: M
authors.lastname: Retz
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D017024:Chemotherapy, Adjuvant / Q000379:methods*; D006801:Humans; D008297:Male; D058990:Molecular Targeted Therapy / Q000379:methods*; D020360:Neoadjuvant Therapy / Q000379:methods; D010166:Palliative Care / Q000379:methods*; D010412:Penile Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents