title: A "big data" view of the tumor "immunome".
abstract: Tumors are complex masses containing not just neoplastic cells but also stromal cells, neovasculature, and a gamut of immune cells. In this issue, Bindea et al. (2013) identify a surprising new "immune landscape" associated with prolonged disease-free survival.
authors.affiliation: Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Center for Regenerative Medicine, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: restifo@nih.gov.
authors.forename: Nicholas P
authors.initials: NP
authors.lastname: Restifo
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D002277:Carcinoma / Q000276:immunology*; D054382:Chemokine CXCL13 / Q000276:immunology*; D015179:Colorectal Neoplasms / Q000276:immunology*; D006801:Humans; D007378:Interleukins / Q000276:immunology*; D009364:Neoplasm Recurrence, Local / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*; D000098546:Interleukin-21
chemical_list: C110663:CXCL13 protein, human; D054382:Chemokine CXCL13; D007378:Interleukins; D000098546:Interleukin-21