title: Mitochondria-specific phosphorescent imaging and tracking in living cells with an AIPE-active iridium(III) complex.
abstract: An AIPE-active iridium(III) complex was found to possess high specificity for mitochondria, superior photostability, low cytotoxicity, and high resistance to the loss of mitochondrial membrane potential. Thus, this complex can be used for mitochondrial imaging and tracking in living cells.
authors.affiliation: MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, State Key Laboratory of Optoelectronic Materials and Technologies, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, P. R. China. ceschh@mail.sysu.edu.cn.
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
authors.forename: Liping
authors.initials: L
authors.lastname: Qiao
authors.forename: Bole
authors.initials: B
authors.lastname: Yu
authors.forename: Guanying
authors.initials: G
authors.lastname: Li
authors.forename: Chunyuan
authors.initials: C
authors.lastname: Liu
authors.forename: Liangnian
authors.initials: L
authors.lastname: Ji
authors.forename: Hui
authors.initials: H
authors.lastname: Chao
mesh_terms: D002470:Cell Survival; D006367:HeLa Cells; D006801:Humans; D007495:Iridium / Q000737:chemistry*; D049408:Luminescent Agents / Q000737:chemistry*; D008928:Mitochondria / Q000378:metabolism*; D008958:Models, Molecular; D008968:Molecular Conformation; D057054:Molecular Imaging / Q000379:methods*; D009942:Organometallic Compounds / Q000737:chemistry*; D010618:Phenanthrolines / Q000737:chemistry
chemical_list: D049408:Luminescent Agents; D009942:Organometallic Compounds; D010618:Phenanthrolines; D007495:Iridium