title: Retrospective molecular analysis of DIM-1 metallo-β-lactamase discovered in Pseudomonas stutzeri from India in 2000.
abstract: Among 220 clinical isolates of Gram-negative bacilli collected in India during 2000, 22 strains showing elevated imipenem MICs were evaluated for carbapenemase production. One DIM-1-producing Pseudomonas stutzeri isolate was detected, and no other carbapenemase-encoding genes were identified. This detection of a DIM-1-producing P. stutzeri isolate from India predating the finding of this gene in the index Dutch strain and the very recent detection of DIM-1 in Africa suggest an unidentified environmental source of this metallo-β-lactamase gene.
authors.affiliation: JMI Laboratories, North Liberty, Iowa, USA.
authors.forename: Lalitagauri M
authors.initials: LM
authors.lastname: Deshpande
authors.forename: Ronald N
authors.initials: RN
authors.lastname: Jones
authors.forename: Leah N
authors.initials: LN
authors.lastname: Woosley
authors.forename: Mariana
authors.initials: M
authors.lastname: Castanheira
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism*; D007194:India; D008826:Microbial Sensitivity Tests; D044223:Pseudomonas stutzeri / Q000201:enzymology*; D012189:Retrospective Studies; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase