title: [Association of carotid intima-media thickness with traditional cardiovascular risk and metabolic factors].
abstract: BACKGROUND
  Carotid intima-media thickness (IMT) is a surrogate marker of subclinical atherosclerosis and is associated with cardiovascular risk factors (CVRF) AIM: To analyze the association of CVRF and metabolic factors (MF) with IMT, and if the clustering of these factors modify IMT.
  
  
  METHODS
  Cross sectional study in 187 participants aged 46±10 years (53% male) without CV disease. Weight, height, waist circumference (WC), blood pressure, fasting plasma glucose and lipid profile were measured. Abdominal obesity (AOb) was defined by ATP III criteria. Mean carotid IMT was measured at the far wall of the common carotid artery. The cutoff point for an abnormally high IMT was set at the 75th IMT percentile of the sample.
  
  
  RESULTS
  The 75th IMT percentile of the sample was 0.67 mm. In a multivariate analysis four factors were significantly related with a high IMT: age (odds ratio (OR): 5.3, confidence intervals (CI): 2.2-12.9), dyslipidemia (OR: 6.4 CI: 2.3-17.9), systolic blood pressure (OR: 2.9, CI: 1.2-7.1) and AOb (OR: 2.9 (IC: 1.1-7.2). The presence of Oto 4 of these factors was associated with an IMT increment from 0.54 to 0.71 mm (p < 0,001).
  
  
  CONCLUSIONS
  In this sample dyslipidemia, systolic blood pressure and abdominal obesity were the main predictors of a high IMT.
authors.affiliation: Unidad de Cardiología, Servicio de Medicina Interna, Hospital de Carabineros, Chile.
authors.forename: Paola
authors.initials: P
authors.lastname: Varleta
authors.forename: Roberto
authors.initials: R
authors.lastname: Concepción
authors.forename: Patricio
authors.initials: P
authors.lastname: Vargas
authors.forename: Héctor
authors.initials: H
authors.lastname: Casanova
mesh_terms: D000328:Adult; D000368:Aged; D050197:Atherosclerosis / Q000150:complications; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000378:metabolism*; D020212:Carotid Artery Injuries; D017536:Carotid Artery, Common; D059168:Carotid Intima-Media Thickness; D002677:Chile; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome; D008875:Middle Aged; D012307:Risk Factors; D055105:Waist Circumference