title: Metal/N-heterocyclic carbene complexes: opportunities for the development of anticancer metallodrugs.
authors.affiliation: Institut de Chimie de Clermont-Ferrand, UMR CNRS 6296, Université Blaise Pascal, BP 10448, 63000 Clermont-Ferrand (France).
authors.forename: Federico
authors.initials: F
authors.lastname: Cisnetti
authors.forename: Arnaud
authors.initials: A
authors.lastname: Gautier
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D017209:Apoptosis / Q000187:drug effects; D045744:Cell Line, Tumor; D056831:Coordination Complexes / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006367:HeLa Cells; D006571:Heterocyclic Compounds / Q000737:chemistry; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy; D008175:Lung Neoplasms / Q000188:drug therapy; D008670:Metals / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D051379:Mice; D008819:Mice, Nude; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D010051:Ovarian Neoplasms / Q000188:drug therapy; D014183:Transplantation, Heterologous
chemical_list: D000970:Antineoplastic Agents; D056831:Coordination Complexes; D006571:Heterocyclic Compounds; D008670:Metals; C030011:carbene; D008697:Methane
keywords: DNA; N-heterocyclic carbenes; antitumor agents; drug design; proteins