title: Novel graphene flowers modified carbon fibers for simultaneous determination of ascorbic acid, dopamine and uric acid.
abstract: A novel and sensitive carbon fiber electrode (CFE) modified by graphene flowers was prepared and used to simultaneously determine ascorbic acid (AA), dopamine (DA) and uric acid (UA). SEM images showed that beautiful and layer-petal graphene flowers homogeneously bloomed on the surface of CFE. Moreover, sharp and obvious oxidation peaks were found at the obtained electrode when compared with CFE and glassy carbon electrode (GCE) for the oxidation of AA, DA and UA. Also, the linear calibration plots for AA, DA and UA were observed, respectively, in the ranges of 45.4-1489.23 μM, 0.7-45.21 μM and 3.78-183.87 μM in the individual detection of each component. By simultaneously changing the concentrations of AA, DA and UA, their oxidation peaks appeared at -0.05 V, 0.16 V and 2.6 V, and the good linear responses ranges were 73.52-2305.53 μM, 1.36-125.69 μM and 3.98-371.49 μM, respectively. In addition, the obtained electrode showed satisfactory results when applied to the determination of AA, DA and UA in urine and serum samples.
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Industrial Park, Renai Road, Suzhou 215123, PR China.
authors.forename: Jiao
authors.initials: J
authors.lastname: Du
authors.forename: Ruirui
authors.initials: R
authors.lastname: Yue
authors.forename: Fangfang
authors.initials: F
authors.lastname: Ren
authors.forename: Zhangquan
authors.initials: Z
authors.lastname: Yao
authors.forename: Fengxing
authors.initials: F
authors.lastname: Jiang
authors.forename: Ping
authors.initials: P
authors.lastname: Yang
authors.forename: Yukou
authors.initials: Y
authors.lastname: Du
mesh_terms: D001205:Ascorbic Acid / Q000097:blood / Q000652:urine; D015374:Biosensing Techniques / Q000379:methods*; D002244:Carbon / Q000737:chemistry; D004298:Dopamine / Q000097:blood / Q000652:urine; D006108:Graphite / Q000737:chemistry; D006801:Humans; D010084:Oxidation-Reduction; D014527:Uric Acid / Q000097:blood / Q000652:urine
chemical_list: D014527:Uric Acid; D002244:Carbon; D006108:Graphite; D001205:Ascorbic Acid; D004298:Dopamine
keywords: Ascorbic acid; Dopamine; Graphene flowers; Uric acid