title: Refining the notion of maturing out: results from the national epidemiologic survey on alcohol and related conditions.
abstract: OBJECTIVE
  Our aim was to determine if the decrease in drug use disorders with age is attributable to changes in persistence, as implied by the notion of maturing out. Also, we examined the association between role transitions and persistence, recurrence, and new onset of drug use disorders.
  
  
  METHODS
  We performed secondary analysis of the 2 waves of the National Epidemiologic Survey on Alcohol and Related Conditions data (baseline assessment 2001-2002, follow-up conducted 2004-2005). We conducted logistic regressions and multinomial logistic regression to determine the effect of age on wave 2 diagnosis status, as well as the interaction between age and role transitions.
  
  
  RESULTS
  Rates of persistence were stable over the life span, whereas rates of new onset and recurrence decreased with age. Changes in parenthood, marital, and employment status were associated with persistence, new onset, and recurrence. We found an interaction between marital status and age.
  
  
  CONCLUSIONS
  Our findings challenge commonly held notions that the age-related decrease in drug use disorders is attributable to an increase in persistence, and that the effects of role transitions are stronger during young, compared with middle and older, adulthood.
authors.affiliation: Alvaro Vergés, Angela M. Haeny, Timothy J. Trull, Phillip K. Wood, and Kenneth J. Sher are with the Department of Psychological Sciences, University of Missouri-Columbia. Kristina M. Jackson is with the Department of Community Health, Brown University, Providence, RI. Kathleen K. Bucholz and Julia D. Grant are with the School of Medicine, Washington University, St Louis, MO.
authors.forename: Alvaro
authors.initials: A
authors.lastname: Vergés
authors.forename: Angela M
authors.initials: AM
authors.lastname: Haeny
authors.forename: Kristina M
authors.initials: KM
authors.lastname: Jackson
authors.forename: Kathleen K
authors.initials: KK
authors.lastname: Bucholz
authors.forename: Julia D
authors.initials: JD
authors.lastname: Grant
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Trull
authors.forename: Phillip K
authors.initials: PK
authors.lastname: Wood
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Sher
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000375:Aging; D016001:Confidence Intervals; D006306:Health Surveys; D006801:Humans; D016015:Logistic Models; D008137:Longitudinal Studies; D008875:Middle Aged; D016017:Odds Ratio; D012008:Recurrence; D019966:Substance-Related Disorders / Q000453:epidemiology* / Q000523:psychology; D014481:United States / Q000453:epidemiology; D055815:Young Adult