title: Distribution of dopaminergic cell bodies in the median raphe nucleus of the rat brain.
abstract: An increasing amount of data suggests that a dysfunction in dopamine (DA) neurotransmission is involved in the pathophysiology of various neurological and psychiatric disorders. With this in mind, the distribution and connectivity of the dopaminergic system in the rat brain has been studied extensively. So far, little is known about the distribution of DA containing neurons in the median raphe nucleus (MnR). This nucleus is mainly defined by a large population of serotonin containing neurons. Using quantitative immunohistochemistry, we observed the presence of a small number of DA containing neurons in the rat MnR, which was in contrast to a previous report.
authors.affiliation: Department of Translational Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands; Department of Neurosurgery, Maastricht University Medical Center, Maastricht, The Netherlands; European Graduate School of Neuroscience (EURON), Maastricht University Medical Center, Maastricht, The Netherlands. Electronic address: a.jahanshahianvar@maastrichtuniversity.nl.
authors.forename: Ali
authors.initials: A
authors.lastname: Jahanshahi
authors.forename: Harry W M
authors.initials: HW
authors.lastname: Steinbusch
authors.forename: Yasin
authors.initials: Y
authors.lastname: Temel
mesh_terms: D000818:Animals; D059290:Dopaminergic Neurons / Q000166:cytology*; D007150:Immunohistochemistry; D008297:Male; D011903:Raphe Nuclei / Q000166:cytology*; D051381:Rats; D017207:Rats, Sprague-Dawley
keywords: Dopamine; Median raphe nucleus; Tyrosine hydroxylase