title: Incidence and cost of pneumonia in older adults with COPD in the United States.
abstract: OBJECTIVE
  To estimate the incidence of pneumonia by COPD status and the excess cost of inpatient primary pneumonia in elders with COPD.
  
  
  METHODS
  A retrospective, longitudinal study using claims linked to eligibility/demographic data for a 5% sample of fee-for-service Medicare beneficiaries from 2005 through 2007.
  
  
  METHODS
  Incidence rates of pneumonia were calculated for elders with and without COPD and for elders with COPD and coexistent congestive heart failure (CHF). Propensity-score matching with multivariate generalized linear regression was used to estimate the excess direct medical cost of inpatient primary pneumonia in elders with COPD as compared with elders with COPD but without a pneumonia hospitalization.
  
  
  RESULTS
  Elders with COPD had nearly six-times the incidence of pneumonia compared with elders without COPD (167.6/1000 person-years versus 29.5/1000 person-years; RR=5.7, p <0 .01); RR increased to 8.1 for elders with COPD and CHF compared with elders without COPD. The incidence of inpatient primary pneumonia among elders with COPD was 54.2/1000 person-years compared with 7/1000 person-years for elders without COPD; RR=7.7, p<0.01); RR increased to 11.0 for elders with COPD and CHF compared with elders without COPD. The one-year excess direct medical cost of inpatient pneumonia in COPD patients was $ 22,697 ($45,456 in cases vs. $ 22,759 in controls (p <0.01)); 70.2% of this cost was accrued during the quarter of the index hospitalization. During months 13 through 24 following the index hospitalization, the excess direct medical cost was $ 5,941 ($23,215 in cases vs. $ 17,274 in controls, p<0.01).
  
  
  CONCLUSIONS
  Pneumonia occurs more frequently in elders with COPD than without COPD. The excess direct medical cost in elders with inpatient pneumonia extends up to 24 months following the index hospitalization and represents $28,638 in 2010 dollars.
authors.affiliation: Brandeis University, Schneider Institute on Healthcare Systems, Heller School, Waltham, Massachusetts, United States of America.
authors.forename: Marian
authors.initials: M
authors.lastname: Ryan
authors.forename: Jose A
authors.initials: JA
authors.lastname: Suaya
authors.forename: John D
authors.initials: JD
authors.lastname: Chapman
authors.forename: William B
authors.initials: WB
authors.lastname: Stason
authors.forename: Donald S
authors.initials: DS
authors.lastname: Shepard
authors.forename: Cindy Parks
authors.initials: CP
authors.lastname: Thomas
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D011014:Pneumonia / Q000191:economics* / Q000453:epidemiology*; D029424:Pulmonary Disease, Chronic Obstructive / Q000191:economics* / Q000453:epidemiology*; D012189:Retrospective Studies; D014481:United States