title: Beta-band activity in auditory pathways reflects speech localization and recognition in bilateral cochlear implant users.
abstract: In normal-hearing listeners, localization of auditory speech involves stimulus processing in the postero-dorsal pathway of the auditory system. In quiet environments, bilateral cochlear implant (CI) users show high speech recognition performance, but localization of auditory speech is poor, especially when discriminating stimuli from the same hemifield. Whether this difficulty relates to the inability of the auditory system to translate binaural electrical cues into neural signals, or to a functional reorganization of auditory cortical pathways following long periods of binaural deprivation is unknown. In this electroencephalography study, we examined the processing of auditory syllables in postlingually deaf adults with bilateral CIs and in normal-hearing adults. Participants were instructed to either recognize ("recognition" task) or localize ("localization" task) the syllables. The analysis focused on event-related potentials and oscillatory brain responses. N1 amplitudes in CI users were larger in the localization compared with recognition task, suggesting an enhanced stimulus processing effort in the localization task. Linear beamforming of oscillatory activity in CI users revealed stronger suppression of beta-band activity after 200 ms in the postero-dorsal auditory pathway for the localization compared with the recognition task. In normal-hearing adults, effects for longer latency event-related potentials were found, but no effects were observed for N1 amplitudes or beta-band responses. Our study suggests that difficulties in speech localization in bilateral CI users are not reflected in a functional reorganization of cortical auditory pathways. New signal processing strategies of cochlear devices preserving unambiguous binaural cues may improve auditory localization performance in bilateral CI users.
authors.affiliation: Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg, Germany; Department of Psychiatry and Psychotherapy Charité-Universitätsmedizin, Berlin, St. Hedwig Hospital, Große Hamburger Str. 5-11, Berlin, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Senkowski
authors.forename: Ulrich
authors.initials: U
authors.lastname: Pomper
authors.forename: Inga
authors.initials: I
authors.lastname: Fitzner
authors.forename: Andreas Karl
authors.initials: AK
authors.lastname: Engel
authors.forename: Andrej
authors.initials: A
authors.lastname: Kral
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D000704:Analysis of Variance; D001306:Auditory Pathways / Q000503:physiopathology*; D001611:Beta Rhythm / Q000502:physiology*; D001931:Brain Mapping; D019929:Cochlear Implantation / Q000379:methods; D003054:Cochlear Implants; D003638:Deafness / Q000503:physiopathology* / Q000628:therapy; D004569:Electroencephalography; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D013017:Sound Localization / Q000502:physiology*; D013060:Speech; D013067:Speech Perception / Q000502:physiology*
keywords: EEG; beta-band responses; cortical plasticity; deafness; oscillatory activity