title: Adaptation capacity of microcirculatory bed of the skin under conditions of high-frequency rate fractionated automated tibial elongation.
abstract: The status of the microcirculatory bed in the skin in the bone regenerate projection was studied under conditions of fractionated automated tibial elongation by transosteal distraction osteosynthesis at a rate of 3 mm/day in adult mongrel dogs. Histological and physiological data indicated that the distraction period was associated with changes in the functional components of the skin microcirculatory bed. Active neovasculogenesis and formation of additional arteriovenular anastomoses provided sufficient oxygenation of tissues and maintained venous outflow. This led to rapid recovery of the functional potentialities of skin microvessels as early as 1 month after the end of forced fixation.
authors.affiliation: G. A. Ilizarov Russian Research Center of Reconstructive Traumatology and Orthopedics, Ministry of Health and Social Development of Russia, Kurgan, Russia. gorbach.e@mail.ru.
authors.forename: E N
authors.initials: EN
authors.lastname: Gorbach
authors.forename: N A
authors.initials: NA
authors.lastname: Kononovich
mesh_terms: D000818:Animals; D001861:Bone Regeneration / Q000502:physiology*; D004285:Dogs; D005593:Fracture Fixation, Internal / Q000379:methods; D008833:Microcirculation / Q000502:physiology*; D018919:Neovascularization, Physiologic / Q000502:physiology*; D012867:Skin / Q000098:blood supply* / Q000254:growth & development; D012879:Skin Physiological Phenomena; D013977:Tibia / Q000378:metabolism*