title: Glaucoma drainage implant surgery and ocular surface transplant graft preservation.
abstract: Glaucoma may develop or worsen after ocular surface transplantation and often requires surgical management for adequate intraocular pressure control. Traditional glaucoma filtering procedures in patients with prior ocular surface transplant may be problematic for several reasons, which include mechanical disruption of the pre-existing graft, epithelial and stem cell toxicity induced by antifibrotic agents, and increased risk of future corneal transplantation failure. We describe the implantation of a glaucoma drainage implant via a limbal-based conjunctival incision with tube placement in the ciliary sulcus in three eyes of two patients with prior ocular surface transplantation. At a follow-up interval of 3-7 months, all three eyes have excellent postoperative control of intraocular pressure, stable vision, and healthy ocular surface grafts.
authors.affiliation: Illinois Eye & Ear Infirmary, University of Illinois at Chicago School of Medicine , Chicago, Illinois , USA.
authors.forename: Ahmad A
authors.initials: AA
authors.lastname: Aref
authors.forename: Kavitha R
authors.initials: KR
authors.lastname: Sivaraman
authors.forename: Ali R
authors.initials: AR
authors.lastname: Djalilian
mesh_terms: D064591:Allografts; D003316:Corneal Diseases / Q000601:surgery*; D004847:Epithelial Cells / Q000637:transplantation; D005260:Female; D005901:Glaucoma / Q000601:surgery*; D020327:Glaucoma Drainage Implants; D006085:Graft Survival / Q000502:physiology*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D016850:Limbus Corneae / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D019919:Prosthesis Implantation / Q000379:methods; D033581:Stem Cell Transplantation; D014065:Tonometry, Ocular; D055815:Young Adult
keywords: Glaucoma drainage device; glaucoma tube shunt; limbal stem-cell deficiency; limbal stem-cell transplant; ocular surface disease