title: Characterisation of a catalase-negative methicillin-resistant Staphylococcus aureus isolate from a dog.
abstract: A catalase-negative MRSA strain and a methicillin resistant Staphylococcus pseudintermedius strain (MRSP) were isolated from a dog affected by a severe form of pododermatitis. The catalase negative isolate was typed as SCCmec I, PVL negative, ST5 t002 strain. A deletion at position 487 of the kat gene altered the functionality of the catalase enzyme. This is the first report of a catalase-negative MRSA in animals. As catalase test is a rapid assay routinely employed for the identification of staphylococci in clinical microbiology laboratories, the presence of MRSA with this uncommon phenotype may be underestimated. Moreover, catalase-negative staphylococci should be investigated more in-depth in order to assess their virulence.
authors.affiliation: Department of Veterinary Medicine, University of Bari "Aldo Moro", Strada provinciale per Casamassima km. 3, 70010 Valenzano, Bari, Italy. Electronic address: marialaura.corrente@uniba.it.
authors.forename: Marialaura
authors.initials: M
authors.lastname: Corrente
authors.forename: Gianpiero
authors.initials: G
authors.lastname: Ventrella
authors.forename: Maria Fiorella
authors.initials: MF
authors.lastname: Greco
authors.forename: Vito
authors.initials: V
authors.lastname: Martella
authors.forename: Antonio
authors.initials: A
authors.lastname: Parisi
authors.forename: Domenico
authors.initials: D
authors.lastname: Buonavoglia
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics*; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D010544:Peroxidases / Q000235:genetics*; D017384:Sequence Deletion; D013203:Staphylococcal Infections / Q000382:microbiology / Q000662:veterinary*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D010544:Peroxidases; C081610:catalase-peroxidase, bacteria
keywords: Catalase; Dog; MRSA