title: AlCl3-promoted [3 + 2] annulation of cis-2,3-disubstituted cyclopropane 1,1-diesters with isothiocyanates: stereoselective synthesis of densely substituted 2-iminodihydrothiophenes.
abstract: cis-2,3-Disubstituted cyclopropane 1,1-diesters were found to be much more reactive than their corresponding trans-isomers in the AlCl3-promoted [3 + 2]-annulations with isothiocyanates. The reaction with the cis-cyclopropanes proceeded to completion within minutes, providing a variety of densely substituted diastereomerically pure 2-iminodihydrothiophenes in moderate to excellent yields.
authors.affiliation: Key Laboratory of Functionalized Molecular Solids, Ministry of Education, Anhui Key Laboratory of Molecule-Based Materials, Institute of Organic Chemistry, College of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241000, China. gshyang@mail.ahnu.edu.cn chaizhuo@mail.ahnu.edu.cn.
authors.forename: Yongxian
authors.initials: Y
authors.lastname: Sun
authors.forename: Gaosheng
authors.initials: G
authors.lastname: Yang
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Chai
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Mu
authors.forename: Jun
authors.initials: J
authors.lastname: Chai