title: Chronic kidney disease: classification of CKD should be about more than prognosis.
abstract: Cystatin C continues to show its superiority over serum creatinine in predicting mortality among patients with chronic kidney disease (CKD). This superiority is, in part, due to the non-glomerular filtration rate (GFR) determinants of cystatin C associating with CKD risk factors and outcomes. The definition and classification of CKD should not exclusively equate cystatin C with GFR.
authors.affiliation: Division of Nephrology and Hypertension and Division of Epidemiology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Rule
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Glassock
mesh_terms: D015415:Biomarkers / Q000097:blood; D003404:Creatinine / Q000097:blood; D055316:Cystatin C / Q000097:blood*; D005919:Glomerular Filtration Rate; D006801:Humans; D011379:Prognosis; D051436:Renal Insufficiency, Chronic / Q000097:blood / Q000145:classification*; D018570:Risk Assessment
chemical_list: D015415:Biomarkers; D055316:Cystatin C; D003404:Creatinine