title: Synthesis of a metal-free coordinating ring via formation of a cleavable [2]catenane.
abstract: We describe an efficient methodology which allows for the preparation of a macrocycle incorporating a free coordination site. It is based on a transition metal-templated strategy and RCM to provide access to a Cu(I)-complexed [2]catenane consisting of the desired cyclised compound and a cleavable ring. Release of the cleavable ring leads to the formation of the target macrocycle in quantitative yield.
authors.affiliation: Institut de Science et d'Ingénierie Supramoléculaires (ISIS), Université de Strasbourg et CNRS, 8 allée Gaspard Monge, 67000 Strasbourg, France. jpsauvage@unistra.fr.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Niess
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Sauvage
mesh_terms: D043863:Catenanes / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D043863:Catenanes; D047028:Macrocyclic Compounds