title: Biomimetic assembly of the [FeFe] hydrogenase: synthetic mimics in a biological shell.
abstract: Combining synthetic chemistry and biology: A new method that allows the incorporation of synthetic [FeFe] hydrogenase mimics into the apo-hydrogenase is highlighted. Azadithiolato-functionalized model complexes showed similar activity to wild-type enzymes when implemented into the protein.
authors.affiliation: Chair of Inorganic Chemistry I/Bioinorganic Chemistry, Ruhr University Bochum, Universitätsstrasse 150, 44801 Bochum (Germany). ulf.apfel@rub.de.
authors.forename: Ulf-Peter
authors.initials: UP
authors.lastname: Apfel
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Weigand
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry / Q000378:metabolism*; D006859:Hydrogen / Q000737:chemistry / Q000378:metabolism; D006864:Hydrogenase / Q000737:chemistry / Q000378:metabolism*; D007506:Iron-Sulfur Proteins / Q000737:chemistry / Q000378:metabolism*
chemical_list: D007506:Iron-Sulfur Proteins; D006859:Hydrogen; C118830:iron hydrogenase; D006864:Hydrogenase
keywords: dithiolato ligands; hydrogen; hydrogenases; iron; maturase