title: Oxidant-free conversion of primary amines to nitriles.
abstract: An amide-derived NNN-Ru(II) hydride complex catalyzes oxidant-free, acceptorless, and chemoselective dehydrogenation of primary and secondary amines to the corresponding nitriles and imines with liberation of dihydrogen. The catalyst system tolerates oxidizable functionality and is selective for the dehydrogenation of primary amines (-CH2NH2) in the presence of amines without α-CH hydrogens.
authors.affiliation: Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.
authors.forename: Kuei-Nin T
authors.initials: KN
authors.lastname: Tseng
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Rizzi
authors.forename: Nathaniel K
authors.initials: NK
authors.lastname: Szymczak
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry
chemical_list: D000588:Amines; D009570:Nitriles; D009942:Organometallic Compounds