title: Blood Tfh cells come with colors.
abstract: Blood CXCR5⁺ CD4⁺ T cells share phenotypic and functional similarities with T follicular helper cells. Studies by He et al. (2013) and Locci et al. (2013) in this issue of Immunity provide insight into their ontogeny and functionally distinct subsets.
authors.affiliation: Baylor Institute for Immunology Research, Baylor Research Institute, Dallas, TX 75204, USA.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Schmitt
authors.forename: Hideki
authors.initials: H
authors.lastname: Ueno
mesh_terms: D000818:Animals; D000906:Antibodies / Q000276:immunology*; D057134:Antibodies, Neutralizing / Q000096:biosynthesis*; D015483:HIV Antibodies / Q000096:biosynthesis*; D015658:HIV Infections / Q000276:immunology*; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D007156:Immunologic Memory; D061026:Programmed Cell Death 1 Receptor / Q000276:immunology*; D054387:Receptors, CXCR / Q000276:immunology*; D054380:Receptors, CXCR5 / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*
chemical_list: C501896:ACKR3 protein, human; D000906:Antibodies; D057134:Antibodies, Neutralizing; C095085:CXCR5 protein, human; D015483:HIV Antibodies; C105992:PDCD1 protein, human; D061026:Programmed Cell Death 1 Receptor; D054387:Receptors, CXCR; D054380:Receptors, CXCR5