title: Respiratory disease related mortality and morbidity on an island of Greece exposed to perlite and bentonite mining dust.
abstract: A morbidity and mortality study took place, focused on Milos Island, where perlite and bentonite mining sites are located. Official data concerning number and cause of deaths, regarding specific respiratory diseases and the total of respiratory diseases, for both Milos Island and the Cyclades Prefecture were used. Standardized Mortality Ratios (SMRs) were computed, adjusted specifically for age, gender and calendar year. Tests of linear trend were performed. By means of a predefined questionnaire, the morbidity rates of specific respiratory diseases in Milos, were compared to those of the municipality of Oinofita, an industrial region. Chi-square analysis was used and the confounding factors of age, gender and smoking were taken into account, by estimating binary logistic regression models. The SMRs for Pneumonia and Chronic Obstructive Pulmonary Disease (COPD) were found elevated for both genders, although they did not reach statistical significance. For the total of respiratory diseases, a statistically significant SMR was identified regarding the decade 1989-1998. The morbidity study revealed elevated and statistically significant Odds Ratios (ORs), associated with allergic rhinitis, pneumonia, COPD and bronchiectasis. An elevated OR was also identified for asthma. After controlling for age, gender and smoking, the ORs were statistically significant and towards the same direction.
authors.affiliation: Hellenic Center for Disease Control and Prevention (HCDCP), 3-5 Agrafon street, Athens 15235, Greece. stefanos.sampatakakis@gmail.com.
authors.forename: Stefanos
authors.initials: S
authors.lastname: Sampatakakis
authors.forename: Athena
authors.initials: A
authors.lastname: Linos
authors.forename: Eleni
authors.initials: E
authors.lastname: Papadimitriou
authors.forename: Athanasios
authors.initials: A
authors.lastname: Petralias
authors.forename: Archontoula
authors.initials: A
authors.lastname: Dalma
authors.forename: Eirini Saranti
authors.initials: ES
authors.lastname: Papasaranti
authors.forename: Eleni
authors.initials: E
authors.lastname: Christoforidou
authors.forename: Melina
authors.initials: M
authors.lastname: Stoltidis
mesh_terms: D007516:Adenoma, Islet Cell; D000393:Air Pollutants / Q000009:adverse effects; D000537:Aluminum Oxide / Q000009:adverse effects*; D001546:Bentonite / Q000009:adverse effects*; D004391:Dust; D005260:Female; D006115:Greece / Q000453:epidemiology; D006801:Humans; D008297:Male; D008906:Mining; D012140:Respiratory Tract Diseases / Q000139:chemically induced* / Q000453:epidemiology / Q000401:mortality; D012822:Silicon Dioxide / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D000393:Air Pollutants; D004391:Dust; C003076:Perlite; D001546:Bentonite; D012822:Silicon Dioxide; D000537:Aluminum Oxide