title: Regenerative activity of 2-(1'-hydroxy-4'-isopropenyl-1'-methylcyclohexyl-2'-thio) methyl ethanoate gel.
abstract: We studied regenerative activity of a sulfur-containing menthane terpenoid (2-(1'-hydroxy-4'-isopropenyl-1'-methylcyclohexyl-2'-thio) methyl ethanoate) in the form of gels with different concentrations in experimental superficial non-penetrating corneal wound. The examined compound significantly increased the regenerative activity by accelerating the onset and completion of epithelialization. The use of 2% and 3% gel ensured finer scarring.
authors.affiliation: Territorial Organ of the Federal Service on Surveillance in Healthcare and Social Development of the Chuvash Republic; S. N. Fedorov Intersectoral Research and Technology Complex " Eye Microsurgery", Cheboksary branch, Ministry of Health of the Russian Federation, Russia. ir.ak-na@mail.ru.
authors.forename: I V
authors.initials: IV
authors.lastname: Akulina
authors.forename: N A
authors.initials: NA
authors.lastname: Pozdeeva
authors.forename: I A
authors.initials: IA
authors.lastname: Frolychev
authors.forename: A O
authors.initials: AO
authors.lastname: Shikhanov
authors.forename: V N
authors.initials: VN
authors.lastname: Ovchinnikova
mesh_terms: D000818:Animals; D003315:Cornea / Q000187:drug effects* / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D005131:Eye Injuries / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D008297:Male; D039821:Monoterpenes / Q000008:administration & dosage*; D011817:Rabbits; D062326:Re-Epithelialization / Q000187:drug effects*; D044968:Regenerative Medicine; D013864:Thioglycolates / Q000008:administration & dosage*
chemical_list: D039821:Monoterpenes; D013864:Thioglycolates; C000588688:methyl 2-(1'-hydroxy-4'-isopropenyl-1'-methylcyclohexyl-2'-thio)ethanoate