title: Synthesis, spectral features and biological activity of some novel hetarylazo dyes derived from 8-chloro-4-hydroxyl-2-quinolone.
abstract: In this study, 8-chloro-4-hydroxyl-2-quinolone was synthesized from cyclocondensation of corresponding dianilide and subsequently used as a potent coupling component with some diazotized heterocyclic amines. These compounds were characterized by UV-vis, FT-IR, (1)H NMR spectroscopic techniques and elemental analysis. Absorption spectra of these dyes were measured in six polar solvents and discussed with respect to the nature of solvents and substituted groups. The effects of acid, base, temperature and concentration on the visible absorption spectra of the dyes were reported. In addition, the antimicrobial activity of the dyes was explored in detail.
authors.affiliation: Department of Chemistry, Faculty of Sciences University of Guilan, Rasht, Iran. Electronic address: yahyazadeh@guilan.ac.ir.
authors.forename: Asieh
authors.initials: A
authors.lastname: Yahyazadeh
authors.forename: Hessamoddin
authors.initials: H
authors.lastname: Yousefi
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001391:Azo Compounds / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D004396:Coloring Agents / Q000737:chemistry* / Q000494:pharmacology*; D006571:Heterocyclic Compounds / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D015363:Quinolones / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D001391:Azo Compounds; D004396:Coloring Agents; D006571:Heterocyclic Compounds; D015363:Quinolones; D012997:Solvents
keywords: Antimicrobial activity; Azo dye; Hetarylazo; Quinolone; Solvent effect; Substituent effect