title: Factors associated with treatment outcomes in mindfulness-based cognitive therapy for panic disorder.
abstract: OBJECTIVE
  Although the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) for panic disorder (PD) has been studied previously, data on the predictors of treatment outcomes in MBCT for PD are scarce.
  
  
  METHODS
  Eighty patients with PD were screened to analyze treatment outcomes such as MBCT completion, treatment response, and remission after undergoing MBCT for PD. Sociodemographic characteristics, comorbid personality disorders, and baseline medication doses were examined. The study administered the Panic Disorder Severity Scale, Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale and Anxiety Sensitivity Inventory-Revised to patients at baseline and at eight weeks.
  
  
  RESULTS
  Sixty-five participants were enrolled in the present study. Comorbid personality disorder was significantly associated with MBCT non-completion. We found that anxiety sensitivity (AS) improvement after an eight week MBCT program was a statistically significant factor associated with treatment response. Using logistic regression analysis, AS improvement after MBCT showed significant association with PD remission after MBCT.
  
  
  CONCLUSIONS
  Comorbid personality disorders of participants could be a potential predictor of MBCT non-completion. Furthermore, AS improvement after MBCT may predict treatment response and remission after MBCT for PD. However, better designed studies with a larger number of patients are needed to confirm our findings.
authors.affiliation: Department of Psychiatry, CHA Bundang Medical Center, CHA University, 59 Yatap-ro, Bundang-gu, Seongnam 463-712, Korea. leesanghyuk@yahoo.com.
authors.forename: Borah
authors.initials: B
authors.lastname: Kim
authors.forename: Sung Joon
authors.initials: SJ
authors.lastname: Cho
authors.forename: Kang Soo
authors.initials: KS
authors.lastname: Lee
authors.forename: Jun-Yeob
authors.initials: JY
authors.lastname: Lee
authors.forename: Ah Young
authors.initials: AY
authors.lastname: Choe
authors.forename: Ji Eun
authors.initials: JE
authors.lastname: Lee
authors.forename: Tai Kiu
authors.initials: TK
authors.lastname: Choi
authors.forename: Sang-Hyuk
authors.initials: SH
authors.lastname: Lee
mesh_terms: D000328:Adult; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D064866:Mindfulness / Q000379:methods*; D016584:Panic Disorder / Q000628:therapy*; D012959:Socioeconomic Factors; D055815:Young Adult
keywords: Mindfulness-Based Cognitive Therapy; anxiety sensitivity; comorbid personality disorder; panic disorder; treatment outcome