title: High genetic diversity of Staphylococcus aureus in a tertiary care hospital in Southwest Nigeria.
abstract: Phenotypic and genetic characterization of 62 Staphylococcus aureus isolates recovered in Nigeria indicated a high proportion of Panton-Valentine leukocidin-positive isolates and a high genetic diversity among the 22 methicillin-resistant S. aureus. This underlines the need for infection control in Africa to prevent further dissemination of potentially highly virulent and resistant clones.
authors.affiliation: Department of Medical Microbiology and Parasitology, Lagos State University College of Medicine (LASUCOM), Ikeja, Nigeria; BTHDC, Lagos State University Teaching Hospital (LASUTH), Ikeja, Nigeria.
authors.forename: Adeola
authors.initials: A
authors.lastname: Raji
authors.forename: Omorugho
authors.initials: O
authors.lastname: Ojemhen
authors.forename: Uche
authors.initials: U
authors.lastname: Umejiburu
authors.forename: Albert
authors.initials: A
authors.lastname: Ogunleye
authors.forename: Dominique S
authors.initials: DS
authors.lastname: Blanc
authors.forename: Patrick
authors.initials: P
authors.lastname: Basset
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003428:Cross Infection; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D008826:Microbial Sensitivity Tests; D058885:Multilocus Sequence Typing; D009549:Nigeria / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000235:genetics*; D062606:Tertiary Care Centers
chemical_list: D000900:Anti-Bacterial Agents
keywords: Lagos; MRSA; Molecular epidemiology; Nigeria; PVL; Staphylococcus aureus