title: Epidemiological features of hand-foot-and-mouth disease in Shenzhen, China from 2008 to 2010.
abstract: This study analysed the spatio-temporal distribution and propagation of hand-foot-and-mouth disease (HFMD) in Shenzhen from 2008 to 2010. Specifically, we examined the epidemiological data, temporal distribution and spatial distribution, and then the relationship between meteorological, social factors and the number of reported HFMD cases was analysed using Spearman's rank correlation. Finally, a geographically weighted regression model was constructed for the number of reported HFMD cases in 2009. It was found that three independent variables, i.e. the number of reported HFMD cases in 2008 and, annual average temperature and precipitation, had different spatial impacts on the number of reported HFMD cases in 2009. In addition, these variables accounted for the propagation mechanism of HFMD in the centre and east of Shenzhen, where the high incidence rate areas are located. These results will be of great help in understanding the spatio-temporal distribution of HFMD and developing approaches to prevent this disease.
authors.affiliation: State Key Laboratory of Remote Sensing Science,Jointly Sponsored by the Institute of Remote Sensing and Digital Earth of the Chinese Academy of Sciences and Beijing Normal University,Beijing,China.
authors.forename: S
authors.initials: S
authors.lastname: Zheng
authors.affiliation: State Key Laboratory of Remote Sensing Science,Jointly Sponsored by the Institute of Remote Sensing and Digital Earth of the Chinese Academy of Sciences and Beijing Normal University,Beijing,China.
authors.forename: C X
authors.initials: CX
authors.lastname: Cao
authors.affiliation: Shenzhen Center for Disease Control and Prevention, Shenzhen,China.
authors.forename: J Q
authors.initials: JQ
authors.lastname: Cheng
authors.affiliation: Shenzhen Center for Disease Control and Prevention, Shenzhen,China.
authors.forename: Y S
authors.initials: YS
authors.lastname: Wu
authors.affiliation: Shenzhen Center for Disease Control and Prevention, Shenzhen,China.
authors.forename: X
authors.initials: X
authors.lastname: Xie
authors.affiliation: State Key Laboratory of Remote Sensing Science,Jointly Sponsored by the Institute of Remote Sensing and Digital Earth of the Chinese Academy of Sciences and Beijing Normal University,Beijing,China.
authors.forename: M
authors.initials: M
authors.lastname: Xu
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006232:Hand, Foot and Mouth Disease / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008685:Meteorological Concepts; D011891:Rain; D012959:Socioeconomic Factors; D062211:Spatio-Temporal Analysis; D013696:Temperature