title: [The lymph nodes imprint for the diagnosis of lymphoid neoplasms].
abstract: BACKGROUND
  lymphoma is the most frequent lymphoid neoplasm in our country. Its diagnosis is based on histopathological findings. The lymph node imprint has been used for more than 40 years. The aim was to establish the sensitivity, specificity, positive predictive value and negative predictive value of lymph node imprint and estimate the inter-observer rate.
  
  
  METHODS
  we did an observational, retrospective, prolective study, based on the lymph node imprint obtained by excisional biopsies over a period of 6 years.
  
  
  RESULTS
  the inclusion criteria was met on 199 samples, 27.1 % were considered as reactive (n = 54), 16.1 % Hodgkin lymphoma (n = 32), 40.2 % (n = 80) non-Hodgkin lymphoma and 16.6 % (n = 33) as metastatic carcinoma. Comparing with the final histopathology report, the sensitivity and specificity of lymph node imprint were 88 % (0.81-0.95) and 64 % (0.55-0.73) respectively, the positive predictive value was 67 % (0.59-0.76) and the negative predictive value was 86 % (0.79-0.94). The interobserver kappa index was 0.467.
  
  
  CONCLUSIONS
  the lymph node imprint remains as a useful tool for the diagnosis of lymphoid neoplasm. The agreement between observers was acceptable.
authors.affiliation: Departamento de Hematología, Hospital General de México, Secretaría de Salud, Distrito Federal, México, Mexico. leukemiachop@hotmail.com.
authors.forename: Carolina
authors.initials: C
authors.lastname: Peniche-Alvarado
authors.forename: Christian Omar
authors.initials: CO
authors.lastname: Ramos-Peñafiel
authors.forename: Carlos
authors.initials: C
authors.lastname: Martínez-Murillo
authors.forename: Mónica
authors.initials: M
authors.lastname: Romero-Guadarrama
authors.forename: Irma
authors.initials: I
authors.lastname: Olarte-Carrillo
authors.forename: Etta
authors.initials: E
authors.lastname: Rozen-Fuller
authors.forename: Adolfo
authors.initials: A
authors.lastname: Martínez-Tovar
authors.forename: Juan
authors.initials: J
authors.lastname: Collazo-Jaloma
authors.forename: Carlos Alberto
authors.initials: CA
authors.lastname: Mendoza-García
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008223:Lymphoma / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D055815:Young Adult
keywords: excisión del linfoma; ganglio linfático; lymph node excision; lymphatic metastasis; lymphoma; metástasis linfática; predictive value of tests; valor predictivo de las pruebas