title: Morphological characteristics of the terminal villi in placental failure.
abstract: A comparative morphological study of the placentas in spontaneous and induced pregnancy aggravated by placental failure was carried out. Placental failure manifested by shrinkage of the terminal villi, lesser number and section areas of their capillaries, and higher expression of vascular endothelium growth factor and endothelial NO synthase in the syncytiotrophoblast and villous endotheliocytes. The changes were more pronounced in pregnancy developing after in vitro fertilization.
authors.affiliation: V. I. Kulakov Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of the Russian Federation, Moscow, Russia. e_dubova@oparina4.ru.
authors.forename: E A
authors.initials: EA
authors.lastname: Dubova
authors.forename: F B
authors.initials: FB
authors.lastname: Buranova
authors.forename: T A
authors.initials: TA
authors.lastname: Fyodorova
authors.forename: A I
authors.initials: AI
authors.lastname: Shchyogolev
authors.forename: G T
authors.initials: GT
authors.lastname: Sukhikh
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002824:Chorionic Villi / Q000098:blood supply / Q000378:metabolism / Q000473:pathology*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008875:Middle Aged; D018919:Neovascularization, Physiologic; D052250:Nitric Oxide Synthase Type III / Q000378:metabolism; D010922:Placenta Diseases / Q000473:pathology*; D011247:Pregnancy; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism; D055815:Young Adult
chemical_list: C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; C496314:NOS3 protein, human; D052250:Nitric Oxide Synthase Type III