title: First Report of bla(IMP-8) in Raoultella planticola.
abstract: Two carbapenem-resistant Raoultella planticola clinical isolates were isolated from patients with pneumonia and Port-A catheter-related bacteremia, respectively, in Taiwan. These isolates remained susceptible to fluoroquinolone, aminoglycoside, and colistin. Though the two isolates had the same antibiogram, plasmidic carbapenemase blaIMP-8, class 1 integron cassette (dfrA12-orfF-aadA2), and qnrB2, they had different pulsed-field gel electrophoresis patterns, plasmid sizes, and outer membrane protein loss profiles. To our knowledge, this is the first report of blaIMP-8 found in R. planticola. Interestingly, blaIMP-8 is the most common carbapenemase found in Klebsiella pneumoniae in Taiwan. In the literature, carbapenemase genes in R. planticola in each country were also found in carbapenem-resistant Enterobacteriaceae in the same country.
authors.affiliation: Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Sung-Pin
authors.initials: SP
authors.lastname: Tseng
authors.forename: Jann-Tay
authors.initials: JT
authors.lastname: Wang
authors.forename: Chih-Yuan
authors.initials: CY
authors.lastname: Liang
authors.forename: Pei-Shan
authors.initials: PS
authors.lastname: Lee
authors.forename: Yee-Chun
authors.initials: YC
authors.lastname: Chen
authors.forename: Po-Liang
authors.initials: PL
authors.lastname: Lu
mesh_terms: D000368:Aged; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D007711:Klebsiella pneumoniae / Q000201:enzymology; D008297:Male; D008875:Middle Aged; D010462:Peptostreptococcus / Q000201:enzymology*; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: C436760:IMP-8 enzyme; D001618:beta-Lactamases