title: Osseofix® system for percutaneous stabilization of osteoporotic and tumorous vertebral compression fractures - clinical and radiological results after 12 months.
abstract: OBJECTIVE
  Determining whether implantation of an expandable titanium mesh cage (Osseofix® system) is a successful and safe minimally invasive therapy for osteoporotic and tumorous vertebral compression fractures (VCFs).
  
  
  METHODS
  32 patients (25 women, 7 men, mean age 71) with 46 osteoporotic or tumorous VCFs (T6 to L4) from June 2010 to January 2012 were included. All of them were stabilized with the Osseofix® system. Preinterventionally we performed X-ray, MRI, and bone density measurements (DXA). The clinical and radiological results were evaluated preop, postop and 12 months postop based on the visual analog scale (VAS) and the Oswestry Disability Index (ODI), X-ray (Beck Index, Cobb angle) and CT.
  
  
  RESULTS
  There was a significant improvement in pain intensity (VAS) (7.8 to 1.6) as well as a significant reduction in the mean ODI (71.36 % to 30.4 %) after 12 months. The mean kyphotic angle according to Cobb showed significant improvements (12.3° to 10.8°) after 12 months. Postinterventional imaging showed one case of loss of height in a stabilized lumbar vertebral body (2.2 %) in osteoporosis and one case with adjacent fracture (2.2 %) in osteoporosis. We saw no changes in the posterior vertebral wall. Except for one pronounced postoperative hematoma, we saw no surgical complications including no cement leakage.
  
  
  CONCLUSIONS
  The clinical mid-term results are good at a low complication rate. The stabilization of symptomatic osteoporotic and tumorous VCFs with the Osseofix® system is a safe and effective procedure, even in fractures with posterior wall involvement. The Osseofix® system is an interesting alternative to the established procedures of cement augmentation.
  
  
  CONCLUSIONS
  • The Osseofix® system is well suited for stabilizing osteoporotic and tumorous VCFs.• It is a safe and effective procedure without cement leakage and with a low complication rate.• The procedure is an interesting alternative to established cement augmentation procedures.
authors.affiliation: Department of Orthopaedics and Orthopaedic Surgery, University Medicine Greifswald.
authors.forename: S A
authors.initials: SA
authors.lastname: Ender
authors.affiliation: Department of Trauma, Hand and Reconstructive Surgery, University Medicine Rostock.
authors.forename: G
authors.initials: G
authors.lastname: Gradl
authors.affiliation: Department of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald.
authors.forename: M
authors.initials: M
authors.lastname: Ender
authors.affiliation: Department of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald.
authors.forename: S
authors.initials: S
authors.lastname: Langner
authors.affiliation: Department of Orthopaedics and Orthopaedic Surgery, University Medicine Greifswald.
authors.forename: H R
authors.initials: HR
authors.lastname: Merk
authors.affiliation: Department of Orthopaedics and Orthopaedic Surgery, University Medicine Greifswald.
authors.forename: R
authors.initials: R
authors.lastname: Kayser
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001843:Bone Cements / Q000627:therapeutic use*; D005593:Fracture Fixation, Internal / Q000295:instrumentation*; D050815:Fractures, Compression / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D006801:Humans; D058498:Kyphoplasty / Q000295:instrumentation* / Q000379:methods; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D058866:Osteoporotic Fractures / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D011474:Prosthesis Design; D011859:Radiography; D016103:Spinal Fractures / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements