title: Current-density imaging using ultra-low-field MRI with adiabatic pulses.
abstract: Magnetic resonance imaging (MRI) allows measurement of electric current density in an object. The measurement is based on observing how the magnetic field of the current density affects the associated spins. However, as high-field MRI is sensitive to static magnetic field variations of only the field component along the main field direction, object rotations are typically needed to image three-dimensional current densities. Ultra-low-field (ULF) MRI, on the other hand, with B0 on the order of 10-100 μT, allows novel MRI sequences. We present a rotation-free method for imaging static magnetic fields and current densities using ULF MRI. The method utilizes prepolarization pulses with adiabatic switch-off ramps. The technique is designed to reveal complete field and current-density information without the need to rotate the object. The method may find applications, e.g., in conductivity imaging. We present simulation results showing the feasibility of the sequence.
authors.affiliation: Department of Biomedical Engineering and Computational Science, Aalto University School of Science, P.O. Box 12200, FI-00076 AALTO, Finland. Electronic address: jaakko.nieminen@aalto.fi.
authors.forename: Jaakko O
authors.initials: JO
authors.lastname: Nieminen
authors.forename: Koos C J
authors.initials: KC
authors.lastname: Zevenhoven
authors.forename: Panu T
authors.initials: PT
authors.lastname: Vesanen
authors.forename: Yi-Cheng
authors.initials: YC
authors.lastname: Hsu
authors.forename: Risto J
authors.initials: RJ
authors.lastname: Ilmoniemi
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D005240:Feasibility Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional; D060526:Magnetic Fields; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015233:Models, Statistical; D010539:Permeability
keywords: Adiabaticity; Current-density imaging; Prepolarization; Rotation-free; Ultra-low-field MRI