title: Radiographic evaluation of the effect of obesity on alveolar bone in rats with ligature-induced periodontal disease.
abstract: There is evidence that the lack of metabolic control of obese patients may accelerate periodontitis. The aim of this study was to evaluate radiographically the effect of cafeteria-diet-induced obesity on alveolar bone loss in rats subjected to periodontal disease. Twenty male Wistar rats were randomly divided into four groups: 1) control group, 2) control and ligature group; 3) cafeteria group; and 4) cafeteria and ligature group. The animals were evaluated for obesity and euthanized, and the mandible of each rat was removed to perform a radiographic evaluation of alveolar bone loss and its effect on diet-induced obesity. The results showed greater alveolar bone loss in the mice in Group 4 (P<0.01). Thus, we concluded that obese mice, on average, showed greater radiographic evidence of alveolar bone loss than mice undergoing induction of obesity.
authors.affiliation: Biologica Science and Health Center, State University of West Paraná (UNIOESTE), Cascavel, Paraná, Brazil.
authors.forename: Cassiane Merigo
authors.initials: CM
authors.lastname: do Nascimento
authors.forename: Tiago
authors.initials: T
authors.lastname: Cassol
authors.forename: Fernanda Soares
authors.initials: FS
authors.lastname: da Silva
authors.forename: Maria Lucia
authors.initials: ML
authors.lastname: Bonfleur
authors.forename: Carlos Augusto
authors.initials: CA
authors.lastname: Nassar
authors.forename: Patricia Oehlmeyer
authors.initials: PO
authors.lastname: Nassar
keywords: obesity; periodontal disease; radiography