title: The downs and ups of sensory deprivation: evidence for firing rate homeostasis in vivo.
abstract: Homeostatic adjustment of neuronal firing rates is considered a vital mechanism to keep neurons operating in their optimal range despite dynamically changing input. Two studies in this issue of Neuron, Hengen et al. (2013) and Keck et al. (2013), provide evidence for firing rate homeostasis in the neocortex of freely behaving rodents.
authors.affiliation: Department of Neurobiology, Physiology and Behavior, University of California, Davis, Davis, CA 95616, USA.
authors.forename: Hannah I
authors.initials: HI
authors.lastname: Bishop
authors.forename: Karen
authors.initials: K
authors.lastname: Zito
mesh_terms: D000818:Animals; D005260:Female; D008297:Male; D000200:Action Potentials / Q000502:physiology; D006706:Homeostasis / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology; D012683:Sensory Deprivation / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology; D014793:Visual Cortex / Q000502:physiology