title: [Statins and the risk of diabetes].
abstract: Statins have a relevant role in decreasing cardiovascular mortality. Statins are effective in primary and secondary prevention. Recently, it has been suggested that statins may have a diabetogenic effect, because a moderate increase in the risk of newly developed diabetes mellitus was observed. The diabetogenic effect of statins is a group effect and it is dose-dependent, too. The effect of statins which lower the cardiovascular risk attenuates the risk of developing diabetes during statin therapy, too. Hence, statins remain the first line therapy of reaching LDL-cholesterol targets.
authors.affiliation: Szent Imre Egyetemi Oktatókórház Anyagcsere Központ Budapest Tétényi út 12-16. 1115.
authors.forename: Gábor
authors.initials: G
authors.lastname: Simonyi
mesh_terms: D015415:Biomarkers / Q000097:blood; D002318:Cardiovascular Diseases / Q000097:blood / Q000517:prevention & control*; D008078:Cholesterol, LDL / Q000097:blood* / Q000187:drug effects; D048909:Diabetes Complications / Q000097:blood / Q000188:drug therapy* / Q000378:metabolism; D003920:Diabetes Mellitus / Q000139:chemically induced* / Q000378:metabolism / Q000517:prevention & control; D004305:Dose-Response Relationship, Drug; D050171:Dyslipidemias / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D012307:Risk Factors
chemical_list: D015415:Biomarkers; D008078:Cholesterol, LDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors
keywords: cardiovascularis hatás; cardiovasular effect; diabeteskockázat; risk of diabetes; statinok; statins