title: Use of lactate in small animal clinical practice.
abstract: Lactate is a product of anaerobic metabolism. Lactate concentration in blood is used clinically as an indicator of tissue hypoperfusion and hypoxia to determine disease severity, assess response to therapy, and predict outcome. This article reviews lactate physiology, sample collection and processing, and interpretation of lactate concentration in clinical practice.
authors.affiliation: Veterinary Clinical Sciences Department, University of Minnesota College of Veterinary Medicine, 1352 Boyd Avenue, St Paul, MN 55108, USA. Electronic address: Shark009@umn.edu.
authors.forename: Leslie C
authors.initials: LC
authors.lastname: Sharkey
authors.forename: Maxey L
authors.initials: ML
authors.lastname: Wellman
mesh_terms: D000818:Animals; D015415:Biomarkers; D007773:Lactates / Q000097:blood*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012698:Serologic Tests / Q000379:methods / Q000662:veterinary*; D014730:Veterinary Medicine / Q000379:methods*
chemical_list: D015415:Biomarkers; D007773:Lactates
keywords: Hypoperfusion; Hypoxia; Lactate; Lactic acidosis; Metabolic acidosis; d-Lactate; l-Lactate