title: Reconstruction of normal and abnormal gastric electrical sources using a potential based inverse method.
abstract: The use of cutaneous recordings to non-invasively characterize gastric slow waves has had limited clinical acceptance, primarily due to the uncertainty in relating the recorded signal to the underlying gastric slow waves. In this study we aim to distinguish and quantitatively reconstruct different slow wave patterns using an inverse algorithm. Slow wave patterns corresponding to normal, retrograde and uncoupled activity at different frequencies were imposed on a stomach surface model. Gaussian noise (10% peak-to-peak) was added to cutaneous potentials and the Greensite-Tikhonov inverse method was used to reconstruct the potentials on the stomach. The effectiveness of the number or location of electrodes on the accuracy of the inverse solutions was investigated using four different electrode configurations. Results showed the reconstructed solutions were able to reliably distinguish the different slow wave patterns and waves with lower frequency were better correlated to the known solution than those with higher. The use of up to 228 electrodes improved the accuracy of the inverse solutions. However, the use of 120 electrodes concentrated around the stomach was able to achieve similar results. The most efficient electrode configuration for our model involved 120 electrodes with an inter-electrode distance of 32 mm.
authors.affiliation: Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.
authors.forename: J H K
authors.initials: JH
authors.lastname: Kim
authors.forename: P
authors.initials: P
authors.lastname: Du
authors.forename: L K
authors.initials: LK
authors.lastname: Cheng
mesh_terms: D004560:Electricity; D004566:Electrodes; D055724:Electrophysiological Phenomena; D012815:Signal Processing, Computer-Assisted; D013270:Stomach / Q000166:cytology / Q000502:physiology