title: Premature mortality in a Georgian cohort of people with epilepsy.
abstract: Mortality in people with epilepsy has not previously been estimated in Georgia. We identified a prevalent cohort of people with epilepsy from a tertiary referral centre in Tbilisi, Georgia and attempted to establish survivorship status for all. One-way sensitivity analysis estimating mortality rates in those lost to follow-up was also used. Of 1952 people, 1250 (64%) were located; 93 (7%) had died over a median of 11 years follow up. The main cause specific Proportional Mortality Ratios were: underlying diseases (39%) and accidental death (9%). One SUDEP was confirmed with a further 4 possible, but the cause of death was unknown in 47%. The overall SMR was 1.4, with much higher SMRs (up to 12) in young people. The sensitivity analysis suggested an SMR of 3.0.
authors.affiliation: Institute of Neurology and Neuropsychology, Tbilisi, Georgia. Electronic address: teia_k@yahoo.com.
authors.forename: Teia
authors.initials: T
authors.lastname: Kobulashvili
authors.forename: Giorgi
authors.initials: G
authors.lastname: Lomidze
authors.forename: Sofia
authors.initials: S
authors.lastname: Kasradze
authors.forename: Josemir W
authors.initials: JW
authors.lastname: Sander
mesh_terms: D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D004827:Epilepsy / Q000175:diagnosis / Q000208:ethnology* / Q000401:mortality*; D005260:Female; D005500:Follow-Up Studies; D005846:Georgia (Republic) / Q000208:ethnology; D006801:Humans; D008297:Male; D008875:Middle Aged; D061213:Mortality, Premature / Q000208:ethnology*; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult
keywords: PMR; Premature death; Retrospective cohort; SMR