title: Ureaplasma--Are you sitting comfortably?
abstract: The role of Ureaplasma spp. in human disease has been controversial, as these bacteria are commonly isolated as part of the normal genital tract flora. Ureaplasma has been shown to have a causal role in urogenital infections and is associated with significant foetal and neonatal morbidity and mortality when infection occurs during the perinatal period. Although rare, invasive Ureaplasma infection (meningitis, renal abscess, mediastinitis and arthritis) has also been reported in both adults and children. This review outlines the unique microbiological features and various clinical presentations of Ureaplasma infection. It also discusses the treatment options, which in the neonatal period can be particularly challenging.
authors.affiliation: Infectious Diseases Unit, The Royal Children's Hospital Melbourne, Parkville, Victoria 3052, Australia. Electronic address: amanda.gwee@rch.org.au.
authors.forename: Amanda
authors.initials: A
authors.lastname: Gwee
authors.forename: Nigel
authors.initials: N
authors.lastname: Curtis
mesh_terms: D005260:Female; D052776:Female Urogenital Diseases / Q000150:complications / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D008297:Male; D052801:Male Urogenital Diseases / Q000150:complications / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology*; D015995:Prevalence; D016019:Survival Analysis; D014509:Ureaplasma / Q000302:isolation & purification*; D016869:Ureaplasma Infections / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology*
keywords: Child; Genitourinary; Macrolide; Meningitis; Mycoplasma; Neonate; Newborn; Perinatal infections; Pregnancy