title: Family history of immigration from a tuberculosis endemic country and low family income are associated with a higher BCG vaccination coverage in Ile-de-France region, France.
abstract: After withdrawal of multipuncture BCG device from the French market in January 2006, vaccination coverage (VC) with the intradermal device has dropped and since remained sub-optimal in Ile-de-France, the only region of mainland France where BCG is recommended to all children. We conducted a cross-sectional study to identify socio-economic factors associated with BCG VC in children of Paris metropolitan area born after January 2006. Two-stage random sampling was used to include 425 children up to 5 years old from Paris and its suburbs. Information was collected through face-to-face interviews and vaccination status confirmed by a vaccination document. Poisson regression analyzed the association between VC and potential determinants. VC of children from families with the lowest incomes (first quartile of family income/consumption unit (CU) (<883 €) was close to 100% regardless of family origin. In families with higher incomes (≥ 883 €/CU), VC was significantly higher among children born to families from a tuberculosis highly endemic country (98.2%) compared with other children (76.2%) (p=0.004). Children of low socio-economic background as well as those with a family history of immigration, regardless of family income, are correctly identified as being at high risk of tuberculosis and properly vaccinated with BCG in this area.
authors.affiliation: Institut de veille sanitaire, 12, rue du Val d'Osne, 94415 Saint-Maurice cedex, France. Electronic address: jp.guthmann@invs.sante.fr.
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Guthmann
authors.forename: Pierre
authors.initials: P
authors.lastname: Chauvin
authors.forename: Yann
authors.initials: Y
authors.lastname: Le Strat
authors.forename: Marion
authors.initials: M
authors.lastname: Soler
authors.forename: Laure
authors.initials: L
authors.lastname: Fonteneau
authors.forename: Daniel
authors.initials: D
authors.lastname: Lévy-Bruhl
mesh_terms: D000328:Adult; D001500:BCG Vaccine / Q000008:administration & dosage* / Q000276:immunology*; D002675:Child, Preschool; D015331:Cohort Studies; D054242:Emigrants and Immigrants; D004641:Emigration and Immigration; D005260:Female; D006801:Humans; D007182:Income; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010297:Paris; D012959:Socioeconomic Factors; D014376:Tuberculosis / Q000517:prevention & control*; D014611:Vaccination / Q000706:statistics & numerical data*
chemical_list: D001500:BCG Vaccine
keywords: BCG; France; Immunization coverage; Socioeconomic determinants