title: Use of a once-daily NSAID in treatment of cyclic vomiting syndrome.
abstract: Cyclic vomiting syndrome (CVS) is a rare disorder characterized by episodes of intense vomiting and nausea separated by symptom-free periods. We report the case of a 71-year-old man who presented with a long history of poorly controlled CVS whose symptoms resolved with the addition of a once-daily dose of meloxicam, a semi-selective non-steroidal anti-inflammatory drug (NSAID). This is the first report of symptom alleviation in a CVS patient using a once-daily NSAID, as well as one with selectivity to COX-2 inhibition. This is important due to both the increased compliance seen with once-daily medications, as well as the decreased gastrointestinal effects seen with selective COX-2 inhibitors compared to nonselective NSAIDS.
authors.affiliation: Feinberg School of Medicine, Northwestern University, 1913 W. North Ave, Chicago, IL, 60622, USA.
authors.forename: Mahesh K
authors.initials: MK
authors.lastname: Vidula
authors.forename: Anil
authors.initials: A
authors.lastname: Wadhwani
authors.forename: Kaleigh
authors.initials: K
authors.lastname: Roberts
authors.forename: Lyle L
authors.initials: LL
authors.lastname: Berkowitz
mesh_terms: D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D016896:Treatment Outcome; D014839:Vomiting / Q000175:diagnosis* / Q000188:drug therapy*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal