title: Poly(meth)acrylate-based coatings.
abstract: Poly(meth)acrylate coatings for pharmaceutical applications were introduced in 1955 with the launch of EUDRAGIT(®) L and EUDRAGIT(®) S, two types of anionic polymers. Since then, by introducing various monomers into their polymer chains and thus altering their properties, diverse forms with specific characteristics have become available. Today, poly(meth)acrylates function in different parts of the gastrointestinal tract and/or release the drug in a time-controlled manner. This article reviews the properties of various poly(meth)acrylates and discusses formulation issues as well as application possibilities.
authors.affiliation: Evonik Industries AG, Kirschenallee, 64293 Darmstadt, Germany. Electronic address: Kathrin.nollenberger@evonik.com.
authors.forename: Kathrin
authors.initials: K
authors.lastname: Nollenberger
authors.forename: Jessica
authors.initials: J
authors.lastname: Albers
mesh_terms: D002626:Chemistry, Pharmaceutical; D004339:Drug Compounding; D005079:Excipients / Q000737:chemistry; D011109:Polymethacrylic Acids / Q000737:chemistry*; D011208:Powders / Q000737:chemistry
chemical_list: D005079:Excipients; D011109:Polymethacrylic Acids; D011208:Powders
keywords: Coating; Delayed release; Poly(meth)acrylates; Polymer; Sustained release; Taste masking