title: Dystonia associated with lamotrigine therapy: a case report and review of the literature.
abstract: The association of extrapyramidal side effects (EPS) with the use of conventional antipsychotics is well established, however, EPS can occur during treatment with anticonvulsant medications as well. We will present the case of a patient who developed an acute dystonic reaction during treatment with lamotrigine and again during re-challenge with the same agent. We will review common side effects of this medication and the previous reports of lamotrigine-associated dystonias. We will also discuss a possible underlying mechanism.
authors.forename: Paola C
authors.initials: PC
authors.lastname: Marrero-Gonzalez
authors.forename: Orlando L
authors.initials: OL
authors.lastname: Ruano
authors.forename: Glenn
authors.initials: G
authors.lastname: Catalano
authors.affiliation: Mental Health and Behavioral Sciences Service, James A. Haley Veterans Hospital, 13000 Bruce B. Downs, Boulevard #116A, Tampa, Florida 33612. glenn.catalano@va.gov.
authors.forename: Maria C
authors.initials: MC
authors.lastname: Catalano
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001480:Basal Ganglia Diseases / Q000139:chemically induced; D004421:Dystonia / Q000139:chemically induced*; D006801:Humans; D000077213:Lamotrigine; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000150:complications / Q000188:drug therapy; D019966:Substance-Related Disorders / Q000150:complications; D014227:Triazines / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000928:Antidepressive Agents; D014227:Triazines; D000077213:Lamotrigine