title: A comparative study of internal laser-assisted and conventional liposuction: a look at the influence of drugs and major surgery on laboratory postoperative values.
abstract: BACKGROUND
  Liposuction is a type of aesthetic surgery that has been performed on humans for decades. There is not much literature addressing the subject matter of pre- and post-surgery blood parameters, although this information is rather interesting. Documentation on patients who received laser-assisted liposuction treatment is particularly scarce. Until now, there has been no literature showing values of platelets, lymphocytes, and neutrophils after liposuction.
  
  
  OBJECTIVE
  The aim of the work is to analyze and interpret values of platelets, lymphocytes and neutrophils in patient blood before and after liposuction, a surgery in which an extraordinarily large amount of potent drugs are used. Moreover, the aim is to compare values changes in patients of conventional and laser-assisted liposuction.
  
  
  METHODS
  We evaluated standard blood samples in patients prior to and after liposuction. This paper covers the number of platelets, lymphocytes, and neutrophils. A total of 54 patients were examined. Moreover, we compared the change in postoperative values in laser-assisted liposuction patients with the change of values in conventional liposuction patients. A paired two-sided Student's t-test was used for statistical evaluation. P < 0.005 was acknowledged to be statistically significant.
  
  
  RESULTS
  Values of platelets were raised both in conventional and in laser-assisted liposuction patients, but this difference was statistically non-significant and levels of platelets were still normal and within the range of blood levels in healthy patients. Values of neutrophils rose by up to 79.49% ± 7.74% standard deviation (SD) and values of lymphocytes dropped by up to 12.68% ± 5.61% SD. The before/after variances of conventional tumescent local anesthesia liposuction and variations in laser-assisted liposuction were similar for all measured parameters; they also showed no statistically significant differences between before and after surgery. The mean value of total operation time without laser-assistance was 3 hours 42 minutes (± 57 minutes SD, range 2 hours 50 minutes to 5 hours 10 minutes). Surgeries with laser-assistance were on average 16 minutes shorter with a mean duration of 3 hours 26 minutes (± 45 minutes SD, range 2 hours 40 minutes to 4 hours 10 minutes). The difference was not statistically significant (P < 0.06). The mean value of aspirate volume for liposuctions performed without laser support was 2,618 mL (± 633.7 SD, range 700 mL to 3,500 mL). Mean aspirate volume for liposuctions with laser assistance was increased by up to 61 mL (2,677 mL ± 499.5 SD, range 1,800 mL to 3,500 mL). The difference was not statistically significant (P < 0.71).
  
  
  CONCLUSIONS
  We conclude that conventional liposuction and laser-assisted liposuction have a similar influence on platelets, lymphocytes, and neutrophils in patients. Moreover, laser-assisted liposuction seems to be less time consuming than conventional liposuction.
authors.affiliation: Department of Aesthetic Medicine, Faculty of Pharmacy, Medical University of Białystok, Białystok, Poland.
authors.forename: Andrzej Feliks
authors.initials: AF
authors.lastname: Przylipiak
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Galicka
authors.forename: Magdalena
authors.initials: M
authors.lastname: Donejko
authors.forename: Marek
authors.initials: M
authors.lastname: Niczyporuk
authors.forename: Jerzy
authors.initials: J
authors.lastname: Przylipiak
mesh_terms: D000328:Adult; D000772:Anesthesia, Local / Q000379:methods*; D001792:Blood Platelets / Q000378:metabolism; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D015187:Lipectomy / Q000379:methods*; D008214:Lymphocytes / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000378:metabolism; D061646:Operative Time; D011184:Postoperative Period; D016896:Treatment Outcome; D055815:Young Adult
keywords: laser; lipolysis; liposuction; lymphocytes; neutrophils; platelets