title: Kinetic analysis of the HBTM-catalyzed esterification of an enantiopure secondary alcohol.
abstract: A detailed kinetic analysis of the homobenzotetramisole-mediated esterification of the enantiopure secondary alcohol (1R,2S)-2-phenylcyclohexanol is presented. The results of this analysis show that the reaction is first order in the homobenzotetramisole catalyst, first order in (1R,2S)-2-phenylcyclohexanol, and first order in propionic anhydride. Initial rates, the turnover frequency of the catalyst, and "different excess" plots were utilized in this evaluation. Additionally, a "same excess" plot revealed no noticeable catalyst decomposition or product inhibition during the course of the reaction.
authors.affiliation: Department of Chemistry, 1102 Natural Sciences II, University of California-Irvine , Irvine, California, 92697, United States.
authors.forename: Alexander J
authors.initials: AJ
authors.lastname: Wagner
authors.forename: Scott D
authors.initials: SD
authors.lastname: Rychnovsky