title: Ectopic Complete Hydatidiform Mole Presenting as an Adnexal Tumor in a Postmenopausal Patient.
abstract: Hydatidiform mole (HM) is rare in postmenopause, with only 7 cases reported. The occurrence of ectopic HM is also rare, with 26 fully documented tubal cases. We are not aware of any reported cases of ectopic HM in a postmenopausal patient. In a 51-year-old patient with 3 years amenorrhea, surgery revealed a necrotic, hemorrhagic mass involving the right peritubal space. Microscopically, chorionic villi were seen within the hemorrhagic mass accompanied by circumferential trophoblast hyperplasia. Immunohistochemically, p57(kip2) positive nuclei were prominent in the extravillous (intermediate) trophoblast. The HER2 FISH expression was diploid, consistent with the diagnosis of an early complete HM.
authors.affiliation: University of Medicine, Targu Mures, Romania stolnicu@gmx.net.
authors.forename: Simona
authors.initials: S
authors.lastname: Stolnicu
authors.affiliation: University of Medicine, Targu Mures, Romania.
authors.forename: Ágota
authors.initials: Á
authors.lastname: Ilyés
authors.affiliation: San Cecilio University Hospital, Granada, Spain.
authors.forename: Enoe
authors.initials: E
authors.lastname: Quiñónez
authors.affiliation: San Cecilio University Hospital, Granada, Spain.
authors.forename: Francisco F
authors.initials: FF
authors.lastname: Nogales
mesh_terms: D000291:Adnexal Diseases / Q000175:diagnosis* / Q000473:pathology; D002828:Choristoma / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005187:Fallopian Tubes / Q000473:pathology*; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D017698:Postmenopause; D011247:Pregnancy
keywords: ectopic; hydatidiform mole; menopause