title: Effects of pulse current on endurance exercise and its anti-fatigue properties in the hepatic tissue of trained rats.
abstract: Fatigue is synonymous with a wide spectrum of familiar physiological conditions, from pathology and general health, to sport and physical exercise. Strenuous, prolonged exercise training causes fatigue. Although several studies have investigated the effects of electrical stimulation frequency on muscle fatigue, the effects of percutaneous pulse current stimulation on fatigue in the hepatic tissue of trained rats is still unclear. In order to find an effective strategy to prevent fatigue or enhance recovery, the effects of pulse current on endurance exercise and its anti-fatigue properties in exercised rats were studied. Rats were subjected to one, three or five weeks of swimming exercise training. After exercise training, rats in the treated group received daily applications of pulse current. All rats were sacrificed after one, three or five weeks of swimming exercise, and the major biochemical indexes were measured in serum and liver. The results demonstrate that pulse current could prolong the exhaustion swimming time, as well as decrease serum ALT, AST and LD levels and liver MDA content. It also elevated serum LDH activity, liver SOD activity and glycogen content. Furthermore, pulse current increased the expression of Bcl-2 and decreased the expression of Bax. Taken together, these results show that pulse current can elevate endurance capacity and facilitate recovery from fatigue.
authors.affiliation: Institute of Military Training Related Medical Science, The 150th Hospital of PLA, Luoyang, Henan, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Chang
authors.forename: Xinfang
authors.initials: X
authors.lastname: Miao
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Ju
authors.forename: Lvgang
authors.initials: L
authors.lastname: Zhu
authors.forename: Changlin
authors.initials: C
authors.lastname: Huang
authors.forename: Tao
authors.initials: T
authors.lastname: Huang
authors.forename: Xincheng
authors.initials: X
authors.lastname: Zuo
authors.forename: Chunfang
authors.initials: C
authors.lastname: Gao
mesh_terms: D000818:Animals; D004558:Electric Stimulation; D005221:Fatigue / Q000378:metabolism / Q000503:physiopathology*; D006003:Glycogen / Q000378:metabolism; D008099:Liver / Q000378:metabolism / Q000502:physiology*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D018763:Muscle Fatigue / Q000502:physiology*; D018482:Muscle, Skeletal / Q000378:metabolism / Q000502:physiology; D010805:Physical Conditioning, Animal / Q000502:physiology*; D010807:Physical Endurance / Q000502:physiology*; D051381:Rats; D013550:Swimming / Q000502:physiology
chemical_list: D008315:Malondialdehyde; D006003:Glycogen