title: A novel and photostable pH probe for selectively staining nuclei in living cells.
abstract: A novel pH probe based on hemi-cyanine was synthesized, which displays extremely large Stokes shift (122 nm) and good photostability. The probe responds to basic pH (pKa 8.32) with a colorimetric and fluorescence turn-on signal. Interestingly, the probe has good cell membrane permeability and could selectively stain nuclei in living cells.
authors.affiliation: Department of Chemistry and Material Sciences, Hubei Engineering University, Xiaogan 432000, P. R. China. zlt1981@126.com.
authors.forename: Lintao
authors.initials: L
authors.lastname: Zeng
authors.forename: Ne
authors.initials: N
authors.lastname: Fan
authors.forename: Jiayu
authors.initials: J
authors.lastname: Zha
authors.forename: Xichao
authors.initials: X
authors.lastname: Hu
authors.forename: Boqiao
authors.initials: B
authors.lastname: Fu
authors.forename: Caiqin
authors.initials: C
authors.lastname: Qin
authors.forename: Liang
authors.initials: L
authors.lastname: Wang
mesh_terms: D002467:Cell Nucleus / Q000378:metabolism*; D004396:Coloring Agents; D006863:Hydrogen-Ion Concentration; D015335:Molecular Probes; D013050:Spectrometry, Fluorescence
chemical_list: D004396:Coloring Agents; D015335:Molecular Probes