title: First Iranian imported case of dengue.
abstract: Dengue fever, a mosquito-borne flavivirus infection, is endemic in Southeast Asia. Currently, incidences have been increasing among adults. There have been no published reports of dengue fever from Iran. Widespread connection between different countries may predispose them for acquisition of infection. The patient was a 58-year-old Iranian woman with acute unexplained high-grade fever for 4 days, associated with skin rash, after returning from Southeast Asia. CBC showed WBC = 1600/mm(3) and platelet count 99,000/mm(3). The patient also had hematuria. ELISA immunoglobulin M (IgM) antibodies to dengue and serum RT-PCR for dengue virus was positive. The patient managed with conservative treatment and due to good general condition and improvement specific antiviral treatment was not started. She became afebrile at the 3(rd) day of hospitalization and discharged with good general condition on fourth day. She was afebrile after two weeks follow-up. Dengue fever has been increasing among adults. It should be suspected, when a patient presents with acute febrile illness and skin rashes returning from endemic region. Conservative treatment may be conducted in uncomplicated cases.
authors.affiliation: Infectious Diseases and Tropical Medical Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Masoud
authors.initials: M
authors.lastname: Mardani
authors.forename: Farhad
authors.initials: F
authors.lastname: Abbasi
authors.forename: Morteza
authors.initials: M
authors.lastname: Aghahasani
authors.forename: Babak
authors.initials: B
authors.lastname: Ghavam
keywords: Dengue fever; Iran; first case