title: Global profiling of carbonyl metabolites with a photo-cleavable isobaric labeling affinity tag.
abstract: A carbonyl-reactive photo-cleavable isobaric labeling affinity tag can provide a selective, high-throughput, and reproducible approach for the quantitative analysis of aldehyde and ketone metabolites in complex biological samples.
authors.affiliation: Institute for Bioscience and Biotechnology Research (IBBR), University of Maryland, Rockville, MD 20850, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Yuan
authors.forename: James L
authors.initials: JL
authors.lastname: Edwards
authors.forename: Shuwei
authors.initials: S
authors.lastname: Li
mesh_terms: D000447:Aldehydes / Q000737:chemistry* / Q000378:metabolism*; D007202:Indicators and Reagents / Q000737:chemistry; D007659:Ketones / Q000737:chemistry* / Q000378:metabolism*; D055668:Photochemical Processes; D013194:Staining and Labeling / Q000379:methods*; D013379:Substrate Specificity
chemical_list: D000447:Aldehydes; D007202:Indicators and Reagents; D007659:Ketones