title: Facile preparation of ammonium alginate-derived nanofibers carrying diverse therapeutic cargo.
abstract: Alginic acid was converted to a variety of ammonium alginate derivatives carrying diverse chemical cargo such as analgesics, antibiotics, and enzymes. These functional polymers could be fashioned into nanofibrous mats by electrostatic spinning. The therapeutic payload could be released in functional form by a simple ion exchange mechanism. Prospects in wound healing are discussed.
authors.affiliation: The University of Tulsa, Department of Chemistry and Biochemistry, Tulsa, Oklahoma, USA, 74104. ruya-ozer@utulsa.edu justin-chalker@utulsa.edu.
authors.forename: Caitlin E
authors.initials: CE
authors.lastname: Pegg
authors.forename: Gregory H
authors.initials: GH
authors.lastname: Jones
authors.forename: Thushara J
authors.initials: TJ
authors.lastname: Athauda
authors.forename: Ruya R
authors.initials: RR
authors.lastname: Ozer
authors.forename: Justin M
authors.initials: JM
authors.lastname: Chalker
mesh_terms: D000464:Alginates / Q000138:chemical synthesis / Q000737:chemistry*; D064751:Ammonium Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D016503:Drug Delivery Systems; D020723:Glucuronic Acid / Q000138:chemical synthesis / Q000737:chemistry; D006603:Hexuronic Acids / Q000138:chemical synthesis / Q000737:chemistry; D008958:Models, Molecular; D057139:Nanofibers / Q000737:chemistry* / Q000648:ultrastructure; D014945:Wound Healing
chemical_list: D000464:Alginates; D064751:Ammonium Compounds; D006603:Hexuronic Acids; D020723:Glucuronic Acid