title: Rauhut-Currier-type reaction with Morita-Baylis-Hillman carbonates of 2-cyclohexenone and alkylidenemalononitriles to access chromene derivatives.
abstract: An assembly of MBH carbonates of cyclohexen-2-one and alkylidenemalononitriles was investigated by the catalysis of a tertiary amine, which efficiently provides aromatic chromene derivatives with dense functionalities through a domino Rauhut-Currier-type reaction, cyclization, and isomerization process under metal-free conditions.
authors.affiliation: Key Laboratory of Drug-Targeting and Drug Delivery System of the Ministry of Education, Department of Medicinal Chemistry, West China School of Pharmacy and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University , Chengdu, Sichuan 610041, China, and College of Pharmacy, Third Military Medical University , Shapingba, Chongqing 400038, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Peng
authors.forename: Xin
authors.initials: X
authors.lastname: Huang
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Zheng
authors.forename: Ying-Chun
authors.initials: YC
authors.lastname: Chen
mesh_terms: D001578:Benzopyrans / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D003512:Cyclohexanones / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001578:Benzopyrans; D003512:Cyclohexanones; D009570:Nitriles; C028215:2-cyclohexen-1-one; C000945:dicyanmethane