title: Frustrated Lewis pair catalyzed hydroamination of terminal alkynes.
abstract: Catalytic amounts of the Lewis acid B(C6 F5 )3 enable the hydroamination of terminal alkynes by aryl amines to the corresponding enamines. In accord with the results of stoichiometric reactions, the mechanism of this reaction involves a frustrated Lewis pair (FLP). The hydroamination can be followed by an FLP-catalyzed hydrogenation, resulting in a one-pot stepwise synthesis of amine derivatives.
authors.affiliation: Department of Chemistry, University of Toronto, 80 St. George St, Toronto Ontario M5S 3H6 (Canada).
authors.forename: Tayseer
authors.initials: T
authors.lastname: Mahdi
authors.forename: Douglas W
authors.initials: DW
authors.lastname: Stephan
keywords: alkynes; enamines; frustrated Lewis pairs; hydroamination; hydrogenation