title: [Comparison of SCORE and Reynolds cardiovascular risk assessments in a cohort without cardiovascular disease].
abstract: BACKGROUND
  Cardiovascular risk assessment may help in the identification of symptom-free subjects with high cardiovascular risk.
  
  
  OBJECTIVE
  The author studied the correlation between SCORE and Reynolds risk assessment systems based on data from the cardiovascular risk screening program carried out in subjects without cardiovascular disease.
  
  
  METHODS
  Data obtained from 4462 subjects (1977 men and 2485 women; mean age, 47,4 years) were analysed. The comparison was based on risk categories of the SCORE system.
  
  
  RESULTS
  There was a strong correlation between the two scoring systems in the low risk population (under <2% SCORE risk the Spearman rho = 1, p < 0.001). A weak correlation was found in the medium risk group (between 3-4% the Spearman rho = 0.59-0.49, p < 0.001 and between 10-14% the Spearman rho = 0.42, ns.) and a stronger correlation in the high risk group (>15% the Spearmen rho = 0.8, p = 0.017). When correlations were analysed in gender and age categories, the weakest correlation was detected in medium risk women over 40 years of age. In cases when the differences between the two scoring systems were significant, the hsCRP levels were significantly higher (4.1 vs. 5.67 mg/L, p < 0.001).
  
  
  CONCLUSIONS
  Introduction of hsCRP into cardiovascular risk assessments can refine the risk status of symptom-free subjects, especially among intermediate risk middle-age women (two-step risk assessment).
authors.affiliation: Irinyi Szakrendelő Kecskemét Irinyi u. 22. 6000.
authors.forename: Csaba
authors.initials: C
authors.lastname: Móczár
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology* / Q000517:prevention & control; D015331:Cohort Studies; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D011237:Predictive Value of Tests; D015995:Prevalence; D018570:Risk Assessment; D012307:Risk Factors; D017678:Sex Distribution
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein
keywords: Reynolds-score; cardiovascular disease free high risk patient; cardiovascular risk assessment; cardiovascularis kockázatbecslés; hsCRP; tünetmentes nagy kockázat