title: Staged interventional management of a massive thrombus related to coronary artery ectasia in acute coronary syndrome.
abstract: Coronary artery ectasia (CAE), which is reported in 0.3-5.3% of coronary angiograms, is known as a risk factor of acute coronary syndrome (ACS). Optimal treatment of CAE in ACS has not yet been established because of few clinical reports and no randomized trial. We describe a 78-year-old woman in whom thrombolysis with recombinant tissue-plasminogen activator, heparin and dual antiplatelet therapy were performed, and an angiogram after 3 days revealed the disappearance of massive thrombus in the CAE of the left circumflex coronary artery. Staged percutaneous coronary intervention and multidisciplinary procedure are feasible to treat ACS with massive thrombus.
authors.affiliation: Department of Cardiology, Muroran City General Hospital, Yamate-Chou 3-8-1, Muroran, 051-8512, Japan, murohosp131@kujiran.jp.
authors.forename: Makoto
authors.initials: M
authors.lastname: Furugen
authors.forename: Yoshitoki
authors.initials: Y
authors.lastname: Takagawa
mesh_terms: D054058:Acute Coronary Syndrome / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy*; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D006328:Cardiac Catheterization / Q000379:methods; D003131:Combined Modality Therapy; D017023:Coronary Angiography / Q000379:methods; D003328:Coronary Thrombosis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D004108:Dilatation, Pathologic / Q000150:complications / Q000000981:diagnostic imaging; D005260:Female; D005500:Follow-Up Studies; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D018570:Risk Assessment; D015912:Thrombolytic Therapy / Q000379:methods*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional
chemical_list: D006493:Heparin; D010959:Tissue Plasminogen Activator