title: The mismatch between the health research and development (R&D) that is needed and the R&D that is undertaken: an overview of the problem, the causes, and solutions.
abstract: One of the most pressing global health problems is that there is a mismatch between the health research and development (R&D) that is needed and that which is undertaken. The dependence of health R&D on market incentives in the for-profit private sector and the lack of coordination by public and philanthropic funders on global R&D priorities have resulted in a global health R&D landscape that neglects certain products and populations and is characterised, more generally, by a distribution that is not 'needs-driven'. This article provides an overview of the mismatch, its causes, and solutions.
authors.affiliation: Department of Primary and Community Care, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands; Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK; rikviergever@gmail.com.
authors.forename: Roderik F
authors.initials: RF
authors.lastname: Viergever
mesh_terms: D035843:Biomedical Research / Q000458:organization & administration; D002567:Certificate of Need; D003906:Developing Countries; D014943:Global Health; D006292:Health Priorities / Q000458:organization & administration; D006801:Humans; D058069:Neglected Diseases / Q000628:therapy; D017149:Private Sector; D017150:Public Sector; D012109:Research Support as Topic / Q000458:organization & administration
keywords: R&D; agenda; pharmaceutical industry; priorities; research funding