title: Cutaneous B-cell chronic lymphocytic leukaemia resembling a granulomatous rosacea.
abstract: B-cell chronic lymphocytic leukemia (B-CLL) is a low-grade lymphoproliferative disease. Cutaneous involvement of B-CLL is limited and, in most cases, it represents non-specific manifestations related to an impaired immune system. Leukemic skin infiltrates (leukemia cutis) occur in 4-20% of patients. Herein we report the case of a 65-year-old woman with B-CLL presenting with papular, nodular, and plaque skin infiltrates affecting the nose, mimicking granulomatous rosacea. We discuss several aspects of rare cutaneous manifestations of B-CLL involving the face.
authors.affiliation: University of Trieste. nickdimeo@libero.it.
authors.forename: Nicola
authors.initials: N
authors.lastname: di Meo
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Stinco
authors.forename: Giusto
authors.initials: G
authors.lastname: Trevisan
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D019337:Hematologic Neoplasms / Q000150:complications* / Q000532:radiotherapy; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000532:radiotherapy; D008214:Lymphocytes / Q000473:pathology*; D009666:Nose / Q000473:pathology; D012393:Rosacea / Q000175:diagnosis*