title: A multiple cavity malignancy involving the renal capsule, pleura and meninges: A case report and review of the literature.
abstract: Malignant renal subcapsular effusions commonly arise from primary or metastatic renal neoplasms. The current case report presents a rare case of malignancy with a massive renal subcapsular effusion accompanied by a malignant pleural effusion of an unknown primary site, which underwent progression to carcinomatous meningitis during chemotherapy. The type of adenocarcinoma present was determined by effusion cytology. Intravenous chemotherapy (docetaxel plus oxaliplatin and gemcitabine plus cisplatin) were administered; however, the disease still progressed. Time to progression was 9 months during treatment of gefitinib. Comprehensive therapies, including intracavity chemotherapy, immunotherapy and gefitinib, were shown to be effective and prolonged the patient's survival time.
authors.affiliation: The Comprehensive Cancer Center, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu 2l0008, P.R. China.
authors.forename: Li-Jing
authors.initials: LJ
authors.lastname: Zhu
authors.forename: Bao-Rui
authors.initials: BR
authors.lastname: Liu
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Qian
authors.forename: Wei-Wei
authors.initials: WW
authors.lastname: Kong
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: Hu
authors.forename: Juan
authors.initials: J
authors.lastname: DU
authors.forename: Hai-Qing
authors.initials: HQ
authors.lastname: Zhu
keywords: adenocarcinoma; neoplasms; pleural effusion; renal; unknown primary site