title: Bronchial asthma control after argon plasma coagulation turbinectomy in patients with chronic rhinitis.
abstract: Bronchial asthma is frequently accompanied by chronic rhinitis. It has been observed that effective treatment of rhinitis may reduce asthma symptoms. The aim of the study was the evaluation of the control of bronchial asthma symptoms in patients with chronic rhinitis after argon plasma coagulation turbinectomy (APCt). The effect of APCt was assessed in 47 adults with drug-resistant chronic rhinitis and bronchial asthma 3-month post-procedure. Changes of asthma symptoms were scored using Asthma Control Test (ACT). Subjective improvement of nasal congestion 3 months after APCt was observed in 87% and of rhinorrhoea in 75% patients. Rhinomanometry showed 219 ± 19 cm³/s increase of flow and 0.75 ± 0.06 Pa/cm³/s reduction of resistance. The prevalence of patients with insufficient bronchial asthma control decreased from 79 to 4%. The decrease was associated with diminished frequency of eosinophils >20% in nasal cytology from 83% pre-procedure to 28% in the follow-up. The percentage of eosinophils >20% in cytology before APCt increased the chance for asthma control improvement by 22.8 times. Reduction in symptoms of drug-resistant rhinitis after APCt is followed by significant improvement of asthma control. The most beneficial therapeutic effects of APCt are noted in patients with a high rate of eosinophils in nasal cytology.
authors.affiliation: ENT Department, Medical University of Silesia, Francuska Str. 20-24, 40-027, Katowice, Poland, edytajura@interia.pl.
authors.forename: Edyta
authors.initials: E
authors.lastname: Jura-Szołtys
authors.forename: Rafał
authors.initials: R
authors.lastname: Ficek
authors.forename: Joanna
authors.initials: J
authors.lastname: Ficek
authors.forename: Jarosław
authors.initials: J
authors.lastname: Markowski
authors.forename: Jerzy
authors.initials: J
authors.lastname: Chudek
mesh_terms: D000328:Adult; D000368:Aged; D057908:Argon Plasma Coagulation / Q000379:methods*; D001249:Asthma / Q000150:complications / Q000628:therapy*; D002908:Chronic Disease; D015331:Cohort Studies; D004804:Eosinophils / Q000166:cytology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000166:cytology; D011446:Prospective Studies; D012220:Rhinitis / Q000150:complications / Q000601:surgery*; D016896:Treatment Outcome; D014420:Turbinates / Q000601:surgery*; D055815:Young Adult