title: Experimental characterisation for micromechanical modelling of CoCr stent fatigue.
abstract: Fatigue of CoCr alloy stents has become a major concern in recent times, owing to cases of premature fracture, often driven by microstructural phenomena. This work presents the development of a micromechanical framework for fatigue design, based on experimental characterisation of a biomedical grade CoCr alloy, including both microscopy and mechanical testing. Fatigue indicator parameters (FIPs) within the micromechanical framework are calibrated for the prediction of microstructure-sensitive fatigue crack initiation (FCI). A multi-scale CoCr stent model is developed, including a 3D global J2 continuum stent-artery model and a 2D micromechanical sub-model. Several microstructure realizations for the stent sub-model allow assessment of the effect of crystallographic orientations on stent fatigue crack initiation predictions. Predictions of FCI are compared with traditional Basquin-Goodman total life predictions, revealing more realistic scatter of data for the microstructure-based FIP approach. Comparison of stent predictions with performance of a 316L stent for the same generic design exposes the design as over-conservative for the CoCr alloy. In response, the micromechanical framework is used to modify the stent design for the CoCr alloy, improving design efficiency.
authors.affiliation: Mechanical Engineering, College of Engineering and Informatics, National University of Ireland Galway, Ireland. Electronic address: c.sweeney4@nuigalway.ie.
authors.forename: Caoimhe A
authors.initials: CA
authors.lastname: Sweeney
authors.forename: Barry
authors.initials: B
authors.lastname: O'Brien
authors.forename: Peter E
authors.initials: PE
authors.lastname: McHugh
authors.forename: Sean B
authors.initials: SB
authors.lastname: Leen
mesh_terms: D002138:Calibration; D002858:Chromium Alloys; D020342:Finite Element Analysis; D008422:Materials Testing; D008958:Models, Molecular; D015607:Stents; D013718:Tensile Strength
chemical_list: D002858:Chromium Alloys
keywords: Cobalt alloy; Fatigue; Microstructure; Modelling; Stent