title: An efficient generation of a functionalized tertiary-alkyl radical for copper-catalyzed tertiary-alkylative Mizoroki-Heck type reaction.
abstract: α-Halocarbonyl compounds undergo β-hydrogen elimination to give conjugated olefins in the presence of a transition-metal catalyst. However, a copper/triamine catalyst system can induce the alkylative Mizoroki–Heck reaction of styrenes with tertiary-alkyl halides possessing a withdrawing group under very mild conditions. This reaction provides an efficient synthetic methodology for tertiary-alkylated styrenes.
authors.forename: Takashi
authors.initials: T
authors.lastname: Nishikata
authors.forename: Yushi
authors.initials: Y
authors.lastname: Noda
authors.forename: Ryo
authors.initials: R
authors.lastname: Fujimoto
authors.forename: Tomomi
authors.initials: T
authors.lastname: Sakashita