title: Vitiquinolone--a quinolone alkaloid from Hibiscus vitifolius Linn.
abstract: Phytochemical investigations of the powdered root of Hibiscus vitifolius Linn. (Malvaceae) was extracted successively with n-hexane and chloroform. Analysis of the n-hexane extract by GC-MS led to the identification of twenty-six components by comparison of their mass spectra with GC-MS library data. A novel quinolone alkaloid, vitiquinolone (5) together with eight known compounds viz. β-Amyrin acetate (1), n-octacosanol (2), β-Amyrin (3), stigmasterol (4), xanthyletin (6), alloxanthoxyletin (7), xanthoxyletin (8) and betulinic acid (9) were isolated from chloroform extract by column chromatography over silica gel. The structure of vitiquinolone was established on the basis of spectroscopic methods including UV, IR, 1D, 2D NMR and ESI-MS. The known compounds were identified on the basis of their physical and spectroscopic data as reported in the literature.
authors.affiliation: Department of Chemistry, Regional Research Institute of Unani Medicine, Royapuram, Chennai 600 013, Tamil Nadu, India. Electronic address: samy_durai1978@yahoo.co.in.
authors.forename: D
authors.initials: D
authors.lastname: Ramasamy
authors.forename: A
authors.initials: A
authors.lastname: Saraswathy
mesh_terms: D000470:Alkaloids / Q000032:analysis* / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification; D001578:Benzopyrans / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D003374:Coumarins / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D062126:Databases, Chemical; D020834:Ethnopharmacology; D005233:Fatty Alcohols / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D005410:Flame Ionization; D008401:Gas Chromatography-Mass Spectrometry; D031584:Hibiscus / Q000737:chemistry* / Q000378:metabolism; D007194:India; D008515:Medicine, Ayurvedic; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000032:analysis / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry* / Q000378:metabolism; D015363:Quinolones / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D021241:Spectrometry, Mass, Electrospray Ionization; D013265:Stigmasterol / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D014315:Triterpenes / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism
chemical_list: D000470:Alkaloids; D001578:Benzopyrans; D003374:Coumarins; D005233:Fatty Alcohols; D010936:Plant Extracts; D015363:Quinolones; D014315:Triterpenes; D009828:Oleanolic Acid; C044309:1-octacosanol; D013265:Stigmasterol; C000265:beta-amyrin acetate
keywords: Alloxanthoxyletin; Betulinic acid; Hibiscus vitifolius Linn.; Vitiquinolone; Xanthoxyletin; Xanthyletin