title: Vestibular papillomatosis as a normal vulvar anatomical condition.
abstract: At the beginning of the nineteen-eighties, vulvar vestibular papillomatosis (VVP) was thought to be a human papilloma virus (HPV) disease. Based upon these findings many clinicians have been treating this condition with laser ablation or by topical application of podophyllin or trichloroacetic acid. Currently, most authors believe that VVP should be considered an anatomical variant of the vestibular mucosa and not HPV related. We present a case of VVP in which there was no histological or molecular evidence of HPV; unnecessary treatment should be avoided.
authors.affiliation: National Institute of Medical Sciences and Nutrition.
authors.forename: Jose Manuel
authors.initials: JM
authors.lastname: Diaz Gonzales
authors.forename: Eduwiges
authors.initials: E
authors.lastname: Martinez Luna
authors.forename: Adriana
authors.initials: A
authors.lastname: Pena Romero
authors.forename: Alma
authors.initials: A
authors.lastname: Molina Hernandez
authors.forename: Judith
authors.initials: J
authors.lastname: Dominguez Cherit
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005833:Genital Neoplasms, Female / Q000473:pathology* / Q000821:virology; D006801:Humans; D009092:Mucous Membrane / Q000033:anatomy & histology / Q000473:pathology; D027383:Papillomaviridae / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000473:pathology*; D016133:Polymerase Chain Reaction; D014844:Vulva / Q000033:anatomy & histology* / Q000473:pathology; D014846:Vulvar Neoplasms / Q000473:pathology* / Q000821:virology