title: Brain infarction with a predilection for cerebellum in a patient with double-outlet left ventricle and vascular malformations.
abstract: Double-outlet left ventricle (DOLV) is a rare congenital heart disease characterized by the origin of the great arteries arising predominantly or completely from the left ventricle. In this report, we describe a case with brain infarction with a predilection for cerebellum in a patient with DOLV and vascular malformations. The cerebellar predilection of ischemic lesions appeared to have been caused by hemodynamic effects related to the specific anatomy of the brachiocephalic trunk. This is further supported by our observation that the mean flow velocity was significantly higher in the vertebral arteries than in the common carotid arteries.
authors.affiliation: Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan. Electronic address: yinoue@fc.kuh.kumamoto-u.ac.jp.
authors.forename: Yasuteru
authors.initials: Y
authors.lastname: Inoue
authors.affiliation: Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Watanabe
authors.affiliation: Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
authors.forename: Yukio
authors.initials: Y
authors.lastname: Ando
mesh_terms: D000015:Abnormalities, Multiple; D000368:Aged; D015901:Angiography, Digital Subtraction; D000925:Anticoagulants / Q000627:therapeutic use; D020520:Brain Infarction / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D002526:Cerebellar Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D002531:Cerebellum / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology; D002533:Cerebral Angiography; D038524:Diffusion Magnetic Resonance Imaging; D004310:Double Outlet Right Ventricle / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D020766:Intracranial Embolism / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D018810:Magnetic Resonance Angiography; D054079:Vascular Malformations / Q000150:complications* / Q000175:diagnosis
chemical_list: D000925:Anticoagulants
keywords: Ischemic stroke; deep vein thrombosis; double-outlet left ventricle; dural arteriovenous fistula