title: The role of drug-eluting stents for the treatment of coronary chronic total occlusions.
abstract: First generation drug-eluting stents (DES) had a major impact on our capacity to percutaneously treat coronary chronic total occlusions by significantly reducing the risk for in-stent restenosis compared to bare metal stents. Second generation drug-eluting stents further improved our capacity to treat these complex lesions by providing improved deliverability and enhanced efficacy and safety. The ongoing development of bioabsorbable stents will likely be the next major advancement to improve the durability of chronic total occlusion interventions.
authors.affiliation: VA North Texas Healthcare System, University of Texas Southwestern Medical Center at Dallas, Division of Cardiology 4500 S. Lancaster Rd, Dallas, TX 75216, USA.
authors.forename: Emmanouil S
authors.initials: ES
authors.lastname: Brilakis
authors.forename: Anna
authors.initials: A
authors.lastname: Kotsia
authors.forename: Michael
authors.initials: M
authors.lastname: Luna
authors.forename: Santiago
authors.initials: S
authors.lastname: Garcia
authors.forename: Shuaib M
authors.initials: SM
authors.lastname: Abdullah
authors.forename: Subhash
authors.initials: S
authors.lastname: Banerjee
mesh_terms: D020341:Absorbable Implants; D023903:Coronary Restenosis / Q000517:prevention & control*; D023921:Coronary Stenosis / Q000503:physiopathology / Q000601:surgery*; D054855:Drug-Eluting Stents; D006801:Humans; D062645:Percutaneous Coronary Intervention / Q000379:methods; D011474:Prosthesis Design; D015607:Stents