title: Clival keloid after nasopharyngeal radium irradiation masquerading as skull base malignancy.
abstract: Nonchordomatous lesions of the clivus are rare entities. Nasopharyngeal radium irradiation (NRI) treatment consists of application of radium to the posterior nasopharynx near the orifice of the Eustachian tubes, an area adjacent to the clivus. Here we present a unique case of a patient with a history of NRI 70 years prior to presentation with a space-occupying clival lesion suspicion for a skull-based malignancy. This lesion was resected using an endoscopic endonasal approach. Histopathological analysis revealed a clival keloid, an entity not previously reported in the literature.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Neurological Institute of New Jersey, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.
authors.forename: Vivek V
authors.initials: VV
authors.lastname: Kanumuri
authors.forename: Milap D
authors.initials: MD
authors.lastname: Raikundalia
authors.forename: Mohemmed N
authors.initials: MN
authors.lastname: Khan
authors.forename: Qasim
authors.initials: Q
authors.lastname: Husain
authors.forename: Alejandro
authors.initials: A
authors.lastname: Vasquez
authors.forename: Jean Anderson
authors.initials: JA
authors.lastname: Eloy
mesh_terms: D000368:Aged; D001847:Bone Diseases / Q000175:diagnosis*; D002908:Chronic Disease; D003388:Cranial Fossa, Posterior; D003937:Diagnosis, Differential; D006801:Humans; D007627:Keloid / Q000175:diagnosis*; D008297:Male; D009304:Nasopharyngitis / Q000150:complications / Q000532:radiotherapy; D009305:Nasopharynx; D011878:Radiotherapy / Q000009:adverse effects; D011883:Radium / Q000627:therapeutic use; D012220:Rhinitis / Q000150:complications / Q000532:radiotherapy; D012852:Sinusitis / Q000150:complications / Q000532:radiotherapy; D019292:Skull Base Neoplasms / Q000175:diagnosis*
chemical_list: D011883:Radium
keywords: Skull base; clival lesion; clivus; keloid; nasopharyngeal radium irradiation; radium irradiation