title: Current diagnostic trends in coagulation disorders among dogs and cats.
abstract: The diagnostic workup to differentiate hemorrhage caused by vascular injury from a systemic hemostatic imbalance typically involves a combination of broad screening tests and specific assays. The characterization of 3 overlapping phases of primary hemostasis, secondary hemostasis, and fibrinolysis provides a simple diagnostic framework for evaluating patients with clinical signs of hemorrhage. New techniques such as flow cytometry, thrombin-generation assays, thrombelastography, and anticoagulant drug monitoring are under investigation for veterinary patients; however, their ability to improve diagnosis or treatment requires further study in clinical trials.
authors.affiliation: Comparative Coagulation Section, Animal Health Diagnostic Center, College of Veterinary Medicine, Cornell University, 240 Farrier Road, Ithaca, NY 13501, USA. Electronic address: mbb9@cornell.edu.
authors.forename: Marjory B
authors.initials: MB
authors.lastname: Brooks
authors.forename: James L
authors.initials: JL
authors.lastname: Catalfamo
mesh_terms: D000818:Animals; D001778:Blood Coagulation Disorders / Q000175:diagnosis / Q000662:veterinary*; D002371:Cat Diseases / Q000097:blood / Q000175:diagnosis*; D002415:Cats; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis*; D004285:Dogs
keywords: Coagulopathy; Fibrinolysis; Hemorrhagic disorders; Hemostasis; Platelet aggregometry; Platelet function; Thrombelastography; Thrombin(IIa) generation