title: Characterization of a high-spin non-heme {FeNO}(8) complex: implications for the reactivity of iron nitroxyl species in biology.
abstract: Stable but able: Chemical and electrochemical reduction of a five-coordinate high-spin non-heme {FeNO}(7) complex (see structure: N blue, Fe orange, and O red) generated the first stable high-spin (S=1) non-heme {FeNO}(8) model complex. The finding that the reduction is metal-centered and causes a decrease in FeNO covalency indicates that in biological systems, reduction activates stable non-heme FeNO units for further transformations.
authors.affiliation: Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109 (USA).
authors.forename: Amy L
authors.initials: AL
authors.lastname: Speelman
authors.forename: Nicolai
authors.initials: N
authors.lastname: Lehnert
mesh_terms: D056831:Coordination Complexes / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006418:Heme / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D058085:Iron Compounds / Q000737:chemistry*; D008968:Molecular Conformation; D009569:Nitric Oxide / Q000737:chemistry*; D009589:Nitrogen Oxides / Q000737:chemistry*; D011789:Quantum Theory
chemical_list: D056831:Coordination Complexes; D058085:Iron Compounds; D009589:Nitrogen Oxides; D009569:Nitric Oxide; D006418:Heme; D007501:Iron; C039900:nitroxyl
keywords: bioinorganic chemistry; nitrogen oxides; nitroxyl complexes; non-heme iron; reduction