title: Hypokalemic paralysis as a presenting manifestation of primary Sjögren's syndrome accompanied by vitamin D deficiency.
abstract: Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease characterized by progressive lymphocyte infiltration of the exocrine glands. Overt or latent renal tubular acidosis (RTA) is a common extraglandular manifestation of pSS.Vitamin D deficiency is associated with autoimmune disorders; however, the potential correlation between pSS and vitamin D deficiency is rarely discussed. The current patient presented with distal RTA, hypocalcemia, and hypophosphatemia that were found to be secondary to both vitamin D deficiency and pSS. In patients diagnosed with both distal RTA and vitamin D deficiency, clinicians should consider autoimmune diseases such as pSS, as a possible underlying etiology.
authors.affiliation: Department of Medicine, Kaohsiung Armed Forces General Hospital, Taiwan.
authors.forename: Chen-Yi
authors.initials: CY
authors.lastname: Liao
authors.forename: Chih-Chiang
authors.initials: CC
authors.lastname: Wang
authors.forename: I-Hung
authors.initials: IH
authors.lastname: Chen
authors.forename: Jeng-Chuan
authors.initials: JC
authors.lastname: Shiang
authors.forename: Mei-Yu
authors.initials: MY
authors.lastname: Liu
authors.forename: Ming-Kai
authors.initials: MK
authors.lastname: Tsai
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D007008:Hypokalemia / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010243:Paralysis / Q000175:diagnosis* / Q000209:etiology; D012859:Sjogren's Syndrome / Q000150:complications / Q000175:diagnosis*; D014808:Vitamin D Deficiency / Q000150:complications / Q000175:diagnosis*