title: Streptococcus pneumoniae serotype 6C presenting as recurrent prosthetic knee joint infection in a patient with a history of congenital asplenia and underlying autoimmune disease: a case report and literature review.
abstract: This report describes a case of primary Streptococcus pneumoniae bacteremia with prosthetic joint infection caused by serotype 6C with recurrent infection in a patient with a history of congenital asplenia and underlying autoimmune disease. Isolates from the primary and recurrent infections were determined to be indistinguishable by pulsed-field gel electrophoresis. This study expands the conditions associated with recurrent invasive pneumococcal disease caused by serotype 6C.
authors.affiliation: Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
authors.forename: Amity L
authors.initials: AL
authors.lastname: Roberts
authors.forename: Angela L
authors.initials: AL
authors.lastname: Hewlett
authors.forename: Jigui
authors.initials: J
authors.lastname: Yu
authors.forename: Moon H
authors.initials: MH
authors.lastname: Nahm
authors.forename: Paul D
authors.initials: PD
authors.lastname: Fey
authors.forename: Peter C
authors.initials: PC
authors.lastname: Iwen
mesh_terms: D001327:Autoimmune Diseases; D015373:Bacterial Typing Techniques; D005260:Female; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications*; D007719:Knee Joint / Q000382:microbiology*; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D000081207:Primary Immunodeficiency Diseases; D016459:Prosthesis-Related Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D012008:Recurrence; D013154:Spleen / Q000002:abnormalities*; D013296:Streptococcus pneumoniae / Q000145:classification*
keywords: Prosthetic; Recurrent; Serotype 6C; Streptococcus pneumoniae