title: Applications of basic fibroblastic growth factor (FGF-2, bFGF) in dentistry.
abstract: Recent developments in research have been based on the maintenance and regeneration of natural organs and tissues; among such developments is the use of growth factors (GFs). The use of basic fibroblastic growth factors (bFGF) may be indicated in different disciplines of dentistry such as periodontics and dental traumatology. These cells' ability to induce proliferation and differentiation of cells may make GFs a useful source for the development of natural structures. This mini-review will discuss how bFGF can be beneficial to dentistry in relation to 1) re-implantation/autotransplantation of avulsed teeth and 2) periodontal regeneration.
authors.affiliation: Department of Pediatric Dentistry, School of Dentistry, University of Rome - La Sapienza, Rome, Italy; Private Practice, Rome, Italy.
authors.forename: Ayse B
authors.initials: AB
authors.lastname: Sonmez
authors.forename: Jacopo
authors.initials: J
authors.lastname: Castelnuovo
mesh_terms: D000818:Animals; D003813:Dentistry / Q000639:trends*; D005346:Fibroblast Growth Factors / Q000494:pharmacology*; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D012092:Replantation; D014084:Tooth Avulsion / Q000628:therapy*
chemical_list: D005346:Fibroblast Growth Factors
keywords: ankylosis; avulsion; dentoalveolar trauma; prevention; root resorption; treatment