title: Anatomic and functional outcomes of 25-gauge vitrectomy for repair of eyes with rhegmatogenous retinal detachment complicated by proliferative vitreoretinopathy.
abstract: BACKGROUND
  The purpose of this study was to evaluate the outcome of 25-gauge vitrectomy for repair of rhegmatogenous retinal detachment (RRD) complicated by proliferative vitreoretinopathy (PVR).
  
  
  METHODS
  Twenty-seven eyes of 27 patients who had undergone 25-gauge vitrectomy for grade C PVR were investigated retrospectively. The surgical procedures, anatomic success, and best-corrected visual acuity were assessed.
  
  
  RESULTS
  The mean number of operations was 1.4 (range 1-4). During the 25-gauge vitrectomy, 20-gauge instruments were needed in eleven eyes (40.7%) to remove resilient fibrous preretinal membranes, to extract subretinal proliferations, or to remove or infuse silicone oil. The retina was reattached in 21 eyes (77.8%) after the initial vitrectomy and in 25 eyes (92.6%) at the final examination. The mean best-corrected visual acuity in logarithm of the minimal angle of resolution units was 1.36 ± 0.81 before vitrectomy and 0.79 ± 0.71 at one month, 0.73 ± 0.72 at 3 months, 0.73 ± 0.75 at 6 months, and 0.75 ± 0.78 at 12 months after vitrectomy. The best-corrected visual acuities were significantly improved compared with the preoperative ones at all postoperative assessments (P<0.001).
  
  
  CONCLUSIONS
  Twenty-five gauge vitrectomy is a relatively safe and efficacious method of treating RRD with PVR, although combined use of 20-gauge instruments may be needed for certain surgical procedures.
authors.affiliation: Osaka Rosai Hospital Clinical Research Center for Occupational Sensory Organ Disability, Sakai, Japan.
authors.forename: Chiharu
authors.initials: C
authors.lastname: Iwahashi-Shima
authors.forename: Tatsuhiko
authors.initials: T
authors.lastname: Sato
authors.forename: Hajime
authors.initials: H
authors.lastname: Bando
authors.forename: Toshihide
authors.initials: T
authors.lastname: Ikeda
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Emi
keywords: 25-gauge vitrectomy; hybrid vitrectomy; proliferative vitreoretinopathy; rhegmatogenous retinal detachment; vitrectomy