title: Gastric somatostatinoma: an extremely rare cause of upper gastrointestinal bleeding.
abstract: A 49-year-old woman presented with chronic abdominal discomfort, significant weight loss, and chronic intermittent diarrhea. She suddenly developed massive upper gastrointestinal bleeding and was referred for further treatment. Endoscopy indicated a large mass in the upper gastric body with antral and duodenal bulb involvement. Endosonography showed a large well-defined isoechoic gastric subepithelial mass with multiple intra-abdominal and peripancreatic lymphadenopathy, suspected to be malignant on the basis of fine needle aspiration cytology. The tumor was surgically removed, and histopathology showed typical characteristics of a neuroendocrine tumor. On the basis of immunohistochemical staining, somatostatinoma, a rare neuroendocrine tumor, was diagnosed. Gastrointestinal bleeding is a rare presentation and the stomach is an uncommon tumor location.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Siriraj Hospital, Mahidol University Faculty of Medicine, Bangkok, Thailand.
authors.forename: Varayu
authors.initials: V
authors.lastname: Prachayakul
authors.forename: Pitulak
authors.initials: P
authors.lastname: Aswakul
authors.forename: Morakod
authors.initials: M
authors.lastname: Deesomsak
authors.forename: Ananya
authors.initials: A
authors.lastname: Pongpaibul
keywords: Endosonography; Neuroendocrine tumors; Somatostatinoma; Stomach metastasis