title: Association of apolipoprotein B, apolipoprotein A, and the its ratio with body fat distribution.
abstract: BACKGROUND
  To evaluate the association of apolipoprotein B (apoB), apolipoprotein A (apoA), and apoB/apoA ratio with the body fat indicators in patients with stable angina pectoris (SA).
  
  
  METHODS
  One hundred and twenty two participants aged 40-60 years old, with a mean age of 52.1 ± 7.2 years and SA, were recruited for the present study. Body weight, height, and waist circumference (WC) were measured, and waist to height ratio (WHtR) was calculated. After 12 hours of fasting, a blood sample was obtained and serum levels of apoB and apoA were measured and the apoB/apoA ratio was calculated. These patients underwent an abdominal computerized tomography scan (CTS) to assess visceral and subcutaneous adipose tissue (VAT, SAT). Linear regressions were computed to assess the relation of apoB, apoA, and their ratio with various measurements of adiposity (VAT, SAT, WC, and WHtR), with adjustment for age, sex, and BMI ≥ 25, WC ≥ 80 in women and WC ≥ 90 in men and WHtR ≥ 0.59.
  
  
  RESULTS
  From totally 123 patients with SA with a mean age of 52.1 ± 7.2 years, 44.7% male and 55.3% women were entered. Significant positive associations were found between visceral fat area and the apoB/apoA ratio (P = 0.02, β = 0.2), and significant negative correlations were observed between visceral fat area and apoA concentrations (P = 0.04, β = -0.2).
  
  
  CONCLUSIONS
  As abdominal fat accumulation is associated with other risk factors such as apolipoproteins in ischemic patients, then we most focus on control of these factors.
authors.affiliation: Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Canada.
authors.forename: Masoumeh
authors.initials: M
authors.lastname: Sadeghi
authors.forename: Zahra
authors.initials: Z
authors.lastname: Pourmoghaddas
authors.forename: Ali
authors.initials: A
authors.lastname: Hekmatnia
authors.forename: Hamid
authors.initials: H
authors.lastname: Sanei
authors.forename: Babak
authors.initials: B
authors.lastname: Tavakoli
authors.forename: Andre
authors.initials: A
authors.lastname: Tchernof
authors.forename: Hamidreza
authors.initials: H
authors.lastname: Roohafza
authors.forename: Nizal
authors.initials: N
authors.lastname: Sarrafzadegan
keywords: Apolipoprotein A; apolipoprotein B; apolipoprotein B/apolipoprotein A; cardiovascular disease; intra-abdominal fat