title: Chemical and genetic diversity of Cremanthodium lineare.
abstract: Chemical constituents and evolutionally neutral DNA sequences of six samples of Cremanthodium lineare Maxim., collected in the Sichuan Province of China, were studied. Three samples produced furanoeremophilanes and the other three, eremophilan-8-ones. The chemotypes were found to be correlated with DNA sequence types, suggesting that the chemical diversity observed has a genetic origin. Production of furanoeremophilanes by a Cremanthodium species suggests an evolutionary relationship between Cremanthodium and Ligularia species, and possibly to related genera.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Saito
authors.forename: Mayu
authors.initials: M
authors.lastname: Ichihara
authors.forename: Koji
authors.initials: K
authors.lastname: Takiguchi
authors.forename: Yui
authors.initials: Y
authors.lastname: Tanio
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Okamoto
authors.forename: Ryo
authors.initials: R
authors.lastname: Hanai
authors.forename: Chiaki
authors.initials: C
authors.lastname: Kuroda
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kawahara
authors.forename: Xun
authors.initials: X
authors.lastname: Gong
authors.forename: Motoo
authors.initials: M
authors.lastname: Tori
mesh_terms: D019659:Asteraceae / Q000737:chemistry* / Q000145:classification / Q000235:genetics*; D001483:Base Sequence; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification*; D014644:Genetic Variation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry / Q000235:genetics; D017422:Sequence Analysis, DNA; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D004365:Drugs, Chinese Herbal; D012717:Sesquiterpenes
keywords: Asteraceae; Cremanthodium lineare Maxim.; Diversity; Furanoeremophilane; ITS; Sesquiterpenoid; atpB-rbcL