title: Bispidine as a helix inducing scaffold: examples of helically folded linear peptides.
abstract: We designed and synthesized bispidine-anchored peptides and showed that these peptides as small as (containing four chiral α-amino acid residues) adopt a right handed helical conformation. Bispidine anchored linear peptide adopts a helical conformation in solution and in the solid state.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Delhi, New Delhi-110016, India. h_haridas@hotmail.com.
authors.forename: V
authors.initials: V
authors.lastname: Haridas
authors.forename: Sandhya
authors.initials: S
authors.lastname: Sadanandan
authors.forename: M V S
authors.initials: MV
authors.lastname: Gopalakrishna
authors.forename: M B
authors.initials: MB
authors.lastname: Bijesh
authors.forename: Ram P
authors.initials: RP
authors.lastname: Verma
authors.forename: Srinivas
authors.initials: S
authors.lastname: Chinthalapalli
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Shandilya
mesh_terms: D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry*; D002942:Circular Dichroism; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*; D011392:Proline / Q000737:chemistry; D017433:Protein Structure, Secondary; D013237:Stereoisomerism
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; D010455:Peptides; C495809:bispidine; D011392:Proline