title: Current and emerging therapies for Alzheimer's disease.
abstract: Alzheimer's disease (AD) is a devastating neurodegenerative disorder, with a rapidly increasing worldwide prevalence. Although no cure for AD has yet been found, substantial progress has been made in our understanding of AD pathogenesis. This progress has led to the development of numerous promising compounds in various stages of clinical testing. In this review, the current pharmacologic treatments for AD are discussed in detail, followed by an overview of the main experimental strategies that will shape AD therapeutics over the next decade.
authors.affiliation: Department of Neurology, Yale University School of Medicine, New Haven, Connecticut. Electronic address: haakon.nygaard@yale.edu.
authors.forename: Haakon B
authors.initials: HB
authors.lastname: Nygaard
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy* / Q000628:therapy*; D016229:Amyloid beta-Peptides / Q000378:metabolism; D002800:Cholinesterase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D007116:Immunization, Passive; D016233:Immunotherapy, Active; D058990:Molecular Targeted Therapy
chemical_list: D016229:Amyloid beta-Peptides; D002800:Cholinesterase Inhibitors