title: Clinical and microbiological profile of infectious keratitis in children.
abstract: BACKGROUND
  Infectious keratitis is a sight-threatening condition for children. The purpose of this study was to describe the clinical profile, risk factors and microbiological profile of infectious keratitis in children.
  
  
  METHODS
  Retrospective review of clinical records of patients under 16 years of age with history of microbial keratitis seen at a tertiary referral center. Clinical characteristics, risk factors, visual and surgical outcomes as well as the microbiological profile are analyzed.
  
  
  RESULTS
  Forty-one eyes of 41 patients. Mean age was 8.7 years. Time between the onset of symptoms and ophthalmological examination was 12.7 days. Predisposing factors were found in 78%; ocular trauma was the most common (25%). Visual acuity equal or worse than 20/200 at admission correlated positively with a poorer visual outcome, p=0.002. Positivity of cultures was 34%. Gram-positive bacteria were isolated in 78.5%; Staphylococcus epidermidis (28.6%) was the most common microorganism.
  
  
  CONCLUSIONS
  Our study emphasizes the importance of a prompt diagnosis and treatment of infectious corneal ulcers in children. Trauma and contact lenses were the main predisposing factors. Gram-positive organisms were isolated in the vast majority of cases and visual outcomes are usually poor.
authors.forename: Patricia
authors.initials: P
authors.lastname: Chirinos-Saldaña
authors.forename: Victor Manuel
authors.initials: VM
authors.lastname: Bautista de Lucio
authors.forename: Julio Cesar
authors.initials: JC
authors.lastname: Hernandez-Camarena
authors.forename: Alejandro
authors.initials: A
authors.lastname: Navas
authors.forename: Arturo
authors.initials: A
authors.lastname: Ramirez-Miranda
authors.forename: Lizet
authors.initials: L
authors.lastname: Vizuet-Garcia
authors.forename: Mariana
authors.initials: M
authors.lastname: Ortiz-Casas
authors.forename: Nadia
authors.initials: N
authors.lastname: Lopez-Espinosa
authors.forename: Carolina
authors.initials: C
authors.lastname: Gaona-Juarez
authors.forename: Luis Antonio
authors.initials: LA
authors.lastname: Bautista-Hernandez
authors.affiliation: Cornea and Refractive Surgery Department, Institute of Ophthalmology "Fundación de Asistencia Privada Conde de Valenciana", Mexico City, Mexico. labauh@hotmail.com.
authors.forename: Enrique O
authors.initials: EO
authors.lastname: Graue-Hernandez
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D001419:Bacteria / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D003320:Corneal Ulcer / Q000382:microbiology; D005260:Female; D005658:Fungi / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D007429:Intraocular Pressure / Q000502:physiology; D007634:Keratitis / Q000382:microbiology* / Q000503:physiopathology; D008297:Male; D011379:Prognosis; D012044:Regression Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D014792:Visual Acuity / Q000502:physiology