title: Clinical application of iodine-eluting stent in patients with advanced esophageal cancer.
abstract: The aim of the present study was to compare the clinical effectiveness of an iodine-eluting stent with a conventional stent in patients with advanced esophageal cancer. Patients with malignant esophageal cancer were randomly assigned to receive a conventional stent (group A) or an iodine-eluting stent (group B). Following implantation, the relief from dysphagia, survival time, routine blood tests, thyroid function examination and complications were compared in the two groups. Groups A and B consisted of 36 and 31 patients, respectively. The mean value that the dysphagia score decreased by was significantly lower in group A (0.83) compared with group B (1.65). The median survival time was longer in group B compared with group A (P=0.0022). No significant differences were observed in the severe complications between the two groups (P=0.084). The iodine-eluting esophageal stent is a relatively safe, feasible and effective treatment for malignant esophageal strictures.
authors.affiliation: Key Laboratory of Cancer Prevention and Therapy, Endoscopy Center, Tianjin Medical University, Cancer Institute and Hospital, Tianjin 300060, P.R. China.
authors.forename: Zhenbo
authors.initials: Z
authors.lastname: Dai
authors.forename: Dejun
authors.initials: D
authors.lastname: Zhou
authors.forename: Jianzhang
authors.initials: J
authors.lastname: Hu
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Yunshou
authors.initials: Y
authors.lastname: Lin
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.forename: Fengling
authors.initials: F
authors.lastname: Li
authors.forename: Peng
authors.initials: P
authors.lastname: Liu
authors.forename: Hua
authors.initials: H
authors.lastname: Li
authors.forename: Fuliang
authors.initials: F
authors.lastname: Cao
keywords: esophageal cancer; stent