title: Revision of 120 tibial infected non-unions with bone and soft tissue loss treated with epidermato-fascial osteoplasty according to Umiarov.
abstract: Treatment of tibial infected non-unions with bone and soft tissue loss has to solve three problems: infection, lack of bone continuity and lack of skin coverage. The aims of treatment are infection healing, bone consolidation with preservation of limb length and soft tissue reconstruction. The most important stage in the planning is an accurate débridement. Soft tissue reconstruction can be achieved using plastic surgery, and bone reconstruction is accomplished with bone grafts or induced membrane technique, but these methods may present disadvantages and risks. Epidermato-fascial osteoplasty is a modified procedure of compression-distraction osteosynthesis that was first described by Umiarov in 1982. This procedure offers the advantages of exactly classifying the phases of simultaneous bone and soft tissue regeneration, and of eliminating large tissue losses without previous closure of soft tissues or use of grafts, because the transported fragment takes fascia and skin along during the transport and closes the edges of the soft tissue gap until the epidermic and fascial reconstruction is complete. A total of 120 patients underwent this kind of surgery between 1986 and 2010 and were followed up for 2-26 years. Average age was 34 years (range 21-57 years). Cultures were positive for Staphylococcus in all cases, and for Pseudomonas in 27 cases. Adequate antibiotic therapy was administered in collaboration with the Infectious Diseases Specialist. Tibial bone resection was from 6 to 18cm (average 9.5cm). The Ilizarov apparatus was used with the oblique wire technique for bone transport in all patients. No intraoperative complications were observed. One patient died 40 days after the operation because of pulmonary embolism. The duration of treatment for the remaining 119 patients was 7-18 months. In all cases, infection eradication, healing of regenerate bone, consolidation at the docking site (with the aid of an autoplastic bone graft in only 11 patients), and epidermic and fascial reconstruction were observed, and functional results were very good. These techniques are particularly demanding for the patient and for the surgical team, but our results demonstrate that they can provide excellent outcomes in the management of difficult cases of infected non-unions.
authors.affiliation: Department of Orthopedics and Traumatology, University of Pavia, Pavia, Italy. Electronic address: tinomora@hotmail.com.
authors.forename: Redento
authors.initials: R
authors.lastname: Mora
authors.affiliation: Department of Infectious Diseases, University of Pavia, Pavia, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Maccabruni
authors.affiliation: Department of Orthopedics and Traumatology, University of Pavia, Pavia, Italy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Bertani
authors.affiliation: Department of Orthopedics and Traumatology, University of Pavia, Pavia, Italy.
authors.forename: Gabriella
authors.initials: G
authors.lastname: Tuvo
authors.affiliation: Department of Orthopedics and Traumatology, University of Pavia, Pavia, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Lucanto
authors.affiliation: Department of Orthopedics and Traumatology, University of Pavia, Pavia, Italy.
authors.forename: Luisella
authors.initials: L
authors.lastname: Pedrotti
mesh_terms: D000328:Adult; D016025:Bone Transplantation; D003646:Debridement; D005260:Female; D005592:Fracture Fixation / Q000295:instrumentation / Q000379:methods*; D017102:Fracture Healing; D005597:Fractures, Open / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D005599:Fractures, Ununited / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D023821:Limb Salvage / Q000379:methods*; D008297:Male; D008875:Middle Aged; D019857:Osteogenesis, Distraction; D011859:Radiography; D019651:Plastic Surgery Procedures; D020127:Recovery of Function; D017695:Soft Tissue Injuries; D013530:Surgical Wound Infection / Q000188:drug therapy*; D016896:Treatment Outcome
keywords: Bone loss; Bone regeneration; Compression–distraction techniques; Infected non-unions; Soft tissue loss