title: Electrical stimulation therapy improves sleep respiratory parameters in obstructive sleep apnea syndrome: a meta-analysis.
abstract: Recent clinical trials have shown that electrical stimulation has beneficial effects in obstructive sleep apnea syndrome (OSAS). The purpose of this study was to evaluate the efficacy of electrical stimulation therapy for OSAS with a meta-analysis. The meta-analysis of all relative studies was performed through searching international literature, including PUBMED, CNKI, and EMBASE databases. This literature analysis compared all patients undergoing electrical stimulation therapy with respect to the respiratory disturbance index (RDI) and changes in sleep structure. Six studies were selected involving a total of 91 patients. The meta-analysis indicated that electrical stimulation therapy reduced RDI, longest apnea time, and improved the minimum SaO2. Based on the evidence found, electrical stimulation may be a potential therapy for OSAS, warranting further clinical trials.
authors.affiliation: Department of Rehabilitation, The Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China. gdtjw@21cn.com.
authors.forename: Jie-Wen
authors.initials: JW
authors.lastname: Tan
authors.affiliation: Faculty of Rehabilitation, Zhongshan Medical College, Sun Yat-sen University, Guangzhou, 510089, China.
authors.forename: Wei-Wei
authors.initials: WW
authors.lastname: Qi
authors.affiliation: Department of Rehabilitation, The Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
authors.forename: Rui-Xin
authors.initials: RX
authors.lastname: Ye
authors.affiliation: Department of Rehabilitation, The Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Wu
mesh_terms: D004599:Electric Stimulation Therapy / Q000379:methods*; D006801:Humans; D015656:Respiratory Mechanics / Q000502:physiology*; D012890:Sleep / Q000502:physiology; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology* / Q000628:therapy*