title: Microbial diversity associated with tetrodotoxin production in marine organisms.
abstract: Tetrodotoxin (TTX), is a potent neurotoxin found in genetically diversed organisms. Many TTX producing microorganism have also been isolated from TTX bearing animals. The TTX producing microbes found in four different phylum (Proteobacteria, Actinobacteria, Firmicutes and Bacteroidetes), the Proteobacteria are the dominating one. In most of the cases, TTX producing microbes are found in the intestine of the TTX producing vector indicating the origin of TTX through food chain. This paper reviews the TTX and its analogs and the geographic distribution of TTX in symbiotic microorganism and its production.
authors.affiliation: CIIMAR, Marine and Environmental Research Center, Porto University, Rua dos Bragas, 289, 4050-123 Porto, Portugal. Electronic address: vpratheepa@gmail.com.
authors.forename: V
authors.initials: V
authors.lastname: Pratheepa
authors.forename: Vitor
authors.initials: V
authors.lastname: Vasconcelos
mesh_terms: D000818:Animals; D044822:Biodiversity; D005399:Fishes; D049851:Gastropoda; D012623:Seawater / Q000382:microbiology*; D013779:Tetrodotoxin / Q000378:metabolism*; D014871:Water Microbiology
chemical_list: D013779:Tetrodotoxin
keywords: Gastropods; Microorganism; Puffer fish; TTX analogs; Tetrodotoxin; Vibrio