title: Peptic ulcer bleeding in China: a multicenter endoscopic survey of 1006 patients.
abstract: OBJECTIVE
  We aimed to describe the clinical picture, management and outcomes of Chinese patients with peptic ulcer bleeding (PUB), especially in those with high risks.
  
  
  METHODS
  A multicenter endoscopic survey was conducted. All consecutive patients with endoscopy confirmed PUB from October 2010 to June 2011 were enrolled. Data including patients' gender, age, symptoms and endoscopic findings, Forrest classification, and endoscopic and medical treatment were documented. High-risk ulcer was defined as Forrest grades Ia to IIb upon endoscopy. Rates of rebleeding, surgery and mortality were recorded.
  
  
  RESULTS
  In all, 1006 patients were included. Of these 437 (43.4%) were categorized with high-risk PUB, among whom 110 (25.2%) received endoscopic treatment, and the success rate was 99.1%. Rebleeding rates 1-3 days, 4-5 days and 6-30 days after treatment in high-risk patients who did and did not receive endoscopic treatment were 10.9% versus 10.4%, 3.6% versus 3.7% and 0.9% versus 1.5%, respectively. The surgery rates of high-risk patients with or without endoscopic treatment were 1.8% (2/110) versus 1.8% (6/327). During the 9-month study period, two patients with high-risk PUB died, therefore, the overall mortality rate of high-risk PUB was 0.5% (2/437).
  
  
  CONCLUSIONS
  The study suggests that the proportions of high-risk PUB in China is 43.4%, while rebleeding and surgery rate after endoscopic treatment as well as the mortality rate of high-risk PUB in China are 15.6%, 1.8% and 0.5%, respectively.
authors.affiliation: Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Bai
authors.forename: Yi Qi
authors.initials: YQ
authors.lastname: Du
authors.forename: Dong
authors.initials: D
authors.lastname: Wang
authors.forename: Duo Wu
authors.initials: DW
authors.lastname: Zou
authors.forename: Zhen Dong
authors.initials: ZD
authors.lastname: Jin
authors.forename: Xian Bao
authors.initials: XB
authors.lastname: Zhan
authors.forename: Xiao Yan
authors.initials: XY
authors.lastname: Zhao
authors.forename: Wei Hong
authors.initials: WH
authors.lastname: Sha
authors.forename: Jiang Bin
authors.initials: JB
authors.lastname: Wang
authors.forename: Weng Fei
authors.initials: WF
authors.lastname: Yu
authors.forename: Yi
authors.initials: Y
authors.lastname: Jiang
authors.forename: Li Ping
authors.initials: LP
authors.lastname: Ye
authors.forename: Shu Tian
authors.initials: ST
authors.lastname: Zhang
authors.forename: Li Ya
authors.initials: LY
authors.lastname: Zhou
authors.forename: Min Hu
authors.initials: MH
authors.lastname: Chen
authors.forename: Xiao Feng
authors.initials: XF
authors.lastname: Yu
authors.forename: Jian Wei
authors.initials: JW
authors.lastname: Zheng
authors.forename: Rong Quan
authors.initials: RQ
authors.lastname: Wang
authors.forename: Xiao Jun
authors.initials: XJ
authors.lastname: Huang
authors.forename: Dong Feng
authors.initials: DF
authors.lastname: Chen
authors.forename: Hua Hong
authors.initials: HH
authors.lastname: Wang
authors.forename: De An
authors.initials: DA
authors.lastname: Tian
authors.forename: Nong Hua
authors.initials: NH
authors.lastname: Lu
authors.forename: Xiao Hua
authors.initials: XH
authors.lastname: Hou
authors.forename: Feng
authors.initials: F
authors.lastname: Ji
authors.forename: Ji Yao
authors.initials: JY
authors.lastname: Wang
authors.forename: Yao Zong
authors.initials: YZ
authors.lastname: Yuan
authors.forename: Dai Ming
authors.initials: DM
authors.lastname: Fan
authors.forename: Kai Chun
authors.initials: KC
authors.lastname: Wu
authors.forename: Bo
authors.initials: B
authors.lastname: Jiang
authors.forename: Zhao Shen
authors.initials: ZS
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China / Q000453:epidemiology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000453:epidemiology* / Q000401:mortality; D011446:Prospective Studies
keywords: bleeding; endoscopy; peptic ulcer