title: Single-chain self-folding of synthetic polymers induced by metal-ligand complexation.
abstract: The controlled folding of a single polymer chain is for the first time realized by metal- complexation. α,ω-Bromine functional linear polymers are prepared via activators regenerated by electron transfer (ARGET) ATRP (M¯n,SEC = 5900 g mol(-1) , Đ = 1.07 and 12 000 g mol(-1) , Đ = 1.06) and the end groups of the polymers are subsequently converted to azide functionalities. A copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction is carried out in the presence of a novel triphenylphosphine ligand and the polymers to afford homotelechelic bis-triphenylphosphine polymeric-macroligands (MLs) (M¯n,SEC = 6600 g mol(-1) , Đ = 1.07, and 12 800 g mol(-1) , Đ = 1.06). Single-chain metal complexes (SCMCs) are formed in the presence of Pd(II) ions in highly diluted solution at ambient temperature. The results derived via (1) H and (31) P{(1) H} NMR experiments, SEC, and DLS unambiguously evidence the efficient formation of SCMCs via metal ligand complexation.
authors.affiliation: Preparative Macromolecular Chemistry, Institut für Technische Chemie und Polymerchemie, Karlsruhe Institute of Technology (KIT), Engesserstr. 18, 76128, Karlsruhe, Germany; Institut für Biologische Grenzflächen, Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Willenbacher
authors.forename: Ozcan
authors.initials: O
authors.lastname: Altintas
authors.forename: Peter W
authors.initials: PW
authors.lastname: Roesky
authors.forename: Christopher
authors.initials: C
authors.lastname: Barner-Kowollik
mesh_terms: D000480:Alkynes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D002384:Catalysis; D002850:Chromatography, Gel; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D011108:Polymers / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001386:Azides; D008024:Ligands; D011108:Polymers; D003300:Copper
keywords: macroligands; metal complexes; single-chain folding; synthetic proteins