title: Decreased portal vein flow during Kawasaki disease in a liver transplant patient.
abstract: Abnormalities of liver function tests are frequently documented in patients with Kawasaki disease, but the mechanism responsible for this has not yet been established. Described herein is the case of a 1-year-10-month-old girl who underwent liver transplantation at 11 months of age. Eleven months after transplantation the patient was diagnosed with Kawasaki disease, which was associated with some portal flow reduction, and received i.v. immunoglobulin, after which fever abated with improvement of portal flow to its pre-fever level. Abnormalities of liver function tests in Kawasaki disease patients may occur as a result of inflammation of both the biliary and portal systems. There are no reports on the potential relationship between Kawasaki disease and the portal vein, and accumulation of further data is necessary to better examine this relationship.
authors.affiliation: Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Aomori, Japan; Department of Transplant Surgery, Jichi Medical University, Shimotsuke, Japan.
authors.forename: Taiichi
authors.initials: T
authors.lastname: Wakiya
authors.forename: Taizen
authors.initials: T
authors.lastname: Urahashi
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Ihara
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Sanada
authors.forename: Naoya
authors.initials: N
authors.lastname: Yamada
authors.forename: Noriki
authors.initials: N
authors.lastname: Okada
authors.forename: Kenichi
authors.initials: K
authors.lastname: Hakamada
authors.forename: Koichi
authors.initials: K
authors.lastname: Mizuta
mesh_terms: D001656:Biliary Atresia / Q000601:surgery*; D001783:Blood Flow Velocity / Q000502:physiology*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006975:Hypertension, Portal / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D007223:Infant; D016031:Liver Transplantation; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D011169:Portal Vein / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed; D018608:Ultrasonography, Doppler
keywords: Kawasaki disease; liver; liver transplantation; portal hypertension; portal vein