title: Lipids in innate antiviral defense.
abstract: It is becoming apparent that infections by a major class of viruses, those with envelopes, can be inhibited during their entry at the step of fusion with cellular membranes. In this review, we discuss multiple innate immune mechanisms that have evolved to modify the lipid composition of cellular and viral membranes to inhibit virion fusion of enveloped viruses.
authors.affiliation: Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: john.schoggins@utsouthwestern.edu.
authors.forename: John W
authors.initials: JW
authors.lastname: Schoggins
authors.forename: Glenn
authors.initials: G
authors.lastname: Randall
mesh_terms: D000818:Animals; D006801:Humans; D007113:Immunity, Innate; D008563:Membrane Lipids / Q000378:metabolism*; D014777:Virus Diseases / Q000276:immunology*; D053586:Virus Internalization; D014780:Viruses
chemical_list: D008563:Membrane Lipids