title: Renal cell carcinoma presenting with brain metastasis from a 1.6 cm primary tumor.
abstract: Small renal cell carcinoma (RCC) tumors are believed to have a negligible risk of metastasis. We report on a 77-year-old man presenting with extremity weakness who was found to have a 2.5 cm brain metastasis from a subsequently discovered 1.6 cm clear cell RCC primary tumor. We review what is known about synchronous and metachronous metastasis from small renal tumors and prognostic features informing treatment for such lesions.
authors.affiliation: The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
authors.forename: Heather J
authors.initials: HJ
authors.lastname: Chalfin
authors.forename: Grzegorz T
authors.initials: GT
authors.lastname: Gurda
authors.forename: Hans-Joerg
authors.initials: HJ
authors.lastname: Hammers
authors.forename: George J
authors.initials: GJ
authors.lastname: Netto
authors.forename: Trinity J
authors.initials: TJ
authors.lastname: Bivalacqua
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000556:secondary* / Q000628:therapy; D002292:Carcinoma, Renal Cell / Q000175:diagnosis* / Q000556:secondary* / Q000628:therapy; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D059146:Metastasectomy; D009392:Nephrectomy; D011379:Prognosis; D011878:Radiotherapy; D014057:Tomography, X-Ray Computed