title: Late preterm birth is associated with short-term morbidity but not with adverse neurodevelopmental and physical outcomes at 1 year.
abstract: We compared the neonatal and infant outcomes at one year (Bayley mental and psychomotor development index, and physical growth) of babies who were (n = 63) or were not (n = 100) delivered prior to 37 weeks in women admitted in threatened late preterm labor (34-35(+6) weeks) with a cervix ≤15 mm. The women were part of a clinical trial to investigate the tocolytic effect of the oxytocin antagonist barusiban. Babies born late preterm (34-36(+6) weeks) had a significantly increased risk of short-term morbidity (hepatobiliary disorders, respiratory disorders, metabolic disorders, nervous system disorders, infection; p < 0.05 for each) compared with those born at term, but there were no significant differences in the neurodevelopmental and physical outcomes at one year (p > 0.05 for both one-year outcomes).
authors.affiliation: University of Exeter Medical School, University of Exeter, Exeter, UK.
authors.forename: Alice
authors.initials: A
authors.lastname: Hughes
authors.forename: Gorm
authors.initials: G
authors.lastname: Greisen
authors.forename: Joan-Carles
authors.initials: JC
authors.lastname: Arce
authors.forename: Steven
authors.initials: S
authors.lastname: Thornton
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature; D011247:Pregnancy; D047928:Premature Birth; D012306:Risk
keywords: Preterm birth; long-term outcomes; neonatology; short-term outcomes; tocolysis