title: Blueberry and mulberry juice prevent obesity development in C57BL/6 mice.
abstract: OBJECTIVE
  To establish whether blueberry (Vaccinium ashei) and mulberry (Morus australis Poir) juice, anthocyanin rich fruit juice, may help counteract obesity.
  
  
  METHODS
  And Methods: Four-week-old C57BL/6 mice were fed a high-fat diet (HFD) with or without blueberry and mulberry juice for 12 weeks. Body weight, serum and hepatic lipids, liver and adipose tissues morphology, insulin and leptin were assessed.
  
  
  RESULTS
  Mice fed HFD exhibited increased body weight, insulin resistance, serum and hepatic lipids. In comparison, blueberry and mulberry juice inhibited body weight gain, decreased the serum cholesterol, reduced the resistance to insulin, attenuated lipid accumulation and decreased the leptin secretin.
  
  
  CONCLUSIONS
  These results indicate that blueberry and mulberry juice may help counteract obesity.
authors.affiliation: College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, Zhejiang, China ; Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wu
authors.forename: Qiong
authors.initials: Q
authors.lastname: Tang
authors.forename: Zichun
authors.initials: Z
authors.lastname: Gao
authors.forename: Zhuoping
authors.initials: Z
authors.lastname: Yu
authors.forename: Haizhao
authors.initials: H
authors.lastname: Song
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Zheng
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
mesh_terms: D052242:Adiponectin / Q000097:blood; D052436:Adipose Tissue, White / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D000872:Anthocyanins / Q000032:analysis / Q000494:pharmacology; D001628:Beverages; D029798:Blueberry Plants / Q000737:chemistry*; D001835:Body Weight / Q000187:drug effects; D059305:Diet, High-Fat / Q000009:adverse effects; D004326:Drinking / Q000187:drug effects; D007328:Insulin / Q000097:blood; D020738:Leptin / Q000097:blood; D050356:Lipid Metabolism / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D031625:Morus / Q000737:chemistry*; D009765:Obesity / Q000097:blood / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*
chemical_list: D052242:Adiponectin; D000872:Anthocyanins; D007328:Insulin; D020738:Leptin