title: A laboratory diagnostic approach to hepatobiliary disease in small animals.
abstract: Routine biochemical tests generally include serum enzymes, proteins, and other markers useful for identifying hepatobiliary disease in dogs and cats. Obtaining results outside the reference intervals can occur with direct hepatocellular injury, enzyme induction by hepatocytes or biliary epithelium, or decreased hepatic function. However, detection of biochemical abnormalities does not necessarily indicate clinically significant disease. For a comprehensive approach to detection and treatment of hepatobiliary disease, the laboratory results must be correlated with the history and physical examination findings, diagnostic imaging results, and other assays.
authors.affiliation: IDEXX Laboratories Inc, 300 East Wilson Bridge Road, Suite 200, Worthington, OH 43085, USA. Electronic address: seth-chapman@idexx.com.
authors.forename: Seth E
authors.initials: SE
authors.lastname: Chapman
authors.forename: Roger A
authors.initials: RA
authors.lastname: Hostutler
mesh_terms: D000818:Animals; D001649:Bile Duct Diseases / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D002371:Cat Diseases / Q000097:blood / Q000175:diagnosis*; D002415:Cats; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis*; D004285:Dogs; D008107:Liver Diseases / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D012016:Reference Values
keywords: Bile acids; Bilirubin; Enzymes; Hepatic disease; Proteins