title: Incidence and outcomes of bepridil-induced interstitial pneumonia.
abstract: BACKGROUND
  The incidence of bepridil-induced pulmonary toxicity, such as interstitial pneumonia, is still unknown. The aim of the present study was to evaluate the incidence of bepridil-induced pulmonary toxicity.
  
  
  RESULTS
  A total of 253 patients treated with bepridil between January 2009 and January 2011 were retrospectively evaluated. Eight out of the 222 evaluable patients (male/female: 5/3, age range: 64-97 years, average age: 80.5 years, median age: 81.0 years) showed bepridil-induced pulmonary toxicity.
  
  
  CONCLUSIONS
  The incidence of bepridil-induced pulmonary toxicity was 3.60% in our study population.
authors.affiliation: Department of Respiratory Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan.
authors.forename: Kei
authors.initials: K
authors.lastname: Yamasaki
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yatera
authors.forename: Shingo
authors.initials: S
authors.lastname: Noguchi
authors.forename: Keishi
authors.initials: K
authors.lastname: Oda
authors.forename: Kentarou
authors.initials: K
authors.lastname: Akata
authors.forename: Chinatsu
authors.initials: C
authors.lastname: Nishida
authors.forename: Toshinori
authors.initials: T
authors.lastname: Kawanami
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Kawanami
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishimoto
authors.forename: Shiro
authors.initials: S
authors.lastname: Ono
authors.forename: Yukio
authors.initials: Y
authors.lastname: Wakuta
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mukae
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D015764:Bepridil / Q000009:adverse effects*; D002121:Calcium Channel Blockers / Q000009:adverse effects*; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D000889:Anti-Arrhythmia Agents; D002121:Calcium Channel Blockers; D015764:Bepridil
keywords: Bepridil; Drug-induced interstitial pneumonia; Pulmonary toxicity