title: Systemic capillary leak syndrome: recognition prevents morbidity and mortality.
abstract: Idiopathic systemic capillary leak syndrome (SCLS) is extremely rare but carries a high morbidity and mortality. The diagnosis is made clinically by a classic triad of hypotension, hypoalbuminaemia and haemoconcentration. There have been recent advances in understanding the pathophysiological basis for SCLS and in effective prophylaxis. We report a case of SCLS to increase awareness of the condition and to highlight the benefits of prophylactic intravenous immunoglobulin in this condition.
authors.affiliation: Department of Haematology, The Canberra Hospital, Canberra, Australian Capital Territory, Australia.
authors.forename: D J
authors.initials: DJ
authors.lastname: Rabbolini
authors.forename: N
authors.initials: N
authors.lastname: Ange
authors.forename: G D
authors.initials: GD
authors.lastname: Walters
authors.forename: M
authors.initials: M
authors.lastname: Pidcock
authors.forename: K L
authors.initials: KL
authors.lastname: Randall
mesh_terms: D019559:Capillary Leak Syndrome / Q000097:blood* / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009017:Morbidity
chemical_list: D016756:Immunoglobulins, Intravenous
keywords: intravenous immunoglobulin; oedema; polycythaemia; shock; systemic capillary leak syndrome