title: [Effects of early goal-directed diuresis therapy on the outcomes of critical ill patients].
abstract: OBJECTIVE
  To evaluate the effects of early goal-directed diuresis therapy on the outcomes of critical ill patients.
  
  
  METHODS
  A total of 56 critical patients enrolled received an injection of furosemide 5-40 mg under a precondition of stable hemodynamics. They were divided into two groups:standard group [Central venous pressure (CVP) decreased below 8 mm Hg] (n = 30) and control group (if not) (n = 26) depending on the goal of CVP.And the differences of survival rate, intensive care unit (ICU) days and ventilation days after diuresis therapy were compared between two groups.
  
  
  RESULTS
  The survival rate of standard group was significantly higher than that of control group (96.7% vs 84.6%, P < 0.05) while the ICU days (4.4 ± 3.6 days) and ventilation days (1.2 ± 1.1 days) after diuresis therapy of standard group were significantly shorter than that of control group (12.5 ± 11.7 and 9.8 ± 9.6 days, P < 0.05).
  
  
  CONCLUSIONS
  Early goal-directed diuresis therapy can improve the prognosis of critical ill patients.
authors.affiliation: Department of Surgical Intensive Care Unit, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
authors.forename: Xiu-kai
authors.initials: XK
authors.lastname: Chen
authors.forename: Qi
authors.initials: Q
authors.lastname: Ding
authors.forename: Da-wei
authors.initials: DW
authors.lastname: Liu
authors.forename: Wen-xiong
authors.initials: WX
authors.lastname: Li
authors.forename: Li-feng
authors.initials: LF
authors.lastname: Huang
authors.forename: Feng
authors.initials: F
authors.lastname: Sui
authors.forename: Yue
authors.initials: Y
authors.lastname: Zheng
authors.forename: Song
authors.initials: S
authors.lastname: Zhao
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016638:Critical Illness; D004231:Diuresis; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008875:Middle Aged; D011379:Prognosis; D055815:Young Adult