title: What on "irf" is this gene 4? Irf4 transcription-factor-dependent dendritic cells are required for T helper 2 cell responses in murine skin.
abstract: Interferon regulatory factors play an important role in the transcriptional regulation of immunity. In this issue of Immunity, Kumamoto et al. (2013) and Gao et al. (2013) identify an Irf4-dependent migratory dendritic cell subset required for T helper 2 cell polarization following cutaneous challenge.
authors.affiliation: St. John's Institute of Dermatology, King's College London, London SE1 9RT, UK.
authors.forename: Barry
authors.initials: B
authors.lastname: Flutter
authors.forename: Frank O
authors.initials: FO
authors.lastname: Nestle
mesh_terms: D000818:Animals; D003713:Dendritic Cells / Q000276:immunology*; D007111:Immunity, Cellular; D037181:Lectins, C-Type / Q000276:immunology*; D012867:Skin / Q000276:immunology*; D017206:Strongylida Infections / Q000276:immunology*; D018418:Th2 Cells / Q000276:immunology*
chemical_list: D037181:Lectins, C-Type; C464940:MGL2 protein, mouse