title: Waddlia chondrophila: from biology to pathogenicity.
abstract: Waddlia chondrophila is an emerging pathogen causing miscarriages in humans and abortions in ruminants. The full genome of this Chlamydia-related bacterium has been recently completed, providing new insights into its biology and evolution. Moreover, new cell biology approaches and the use of novel inhibitors have allowed detailed investigations of its interaction with host cells.
authors.affiliation: Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland.
authors.forename: Marie
authors.initials: M
authors.lastname: de Barsy
authors.forename: Gilbert
authors.initials: G
authors.lastname: Greub
mesh_terms: D000022:Abortion, Spontaneous / Q000382:microbiology; D000034:Abortion, Veterinary / Q000382:microbiology; D000818:Animals; D005075:Biological Evolution; D002460:Cell Line; D002473:Cell Wall / Q000235:genetics / Q000378:metabolism; D002689:Chlamydia / Q000472:pathogenicity / Q000502:physiology*; D002690:Chlamydia Infections / Q000382:microbiology; D004734:Energy Metabolism; D016680:Genome, Bacterial; D054884:Host-Pathogen Interactions; D006801:Humans; D042541:Intracellular Space / Q000382:microbiology; D012140:Respiratory Tract Diseases / Q000382:microbiology
keywords: Abs; BCV; Chlamydia-related organism; EBs; ER; Intracellular bacteria; OMP; PG; Pathogenesis; RBs; T3SS; Waddlia chondrophila; aberrant bodies; bacteria containing vacuole; elementary bodies; endoplasmic reticulum; outer membrane protein; p.i.; peptidoglycan; post infection; reticulate bodies; type III secretion system