title: Thrombolytic therapy in Kawasaki disease: a report of four cases.
abstract: Four patients with a thrombus in a coronary artery aneurysm due to Kawasaki disease (KD) were treated at our hospital between 1994 and 2009. All the cases were treated with intravenous coronary thrombolysis (IVCT) therapy and the cases with acute myocardial infarction were treated with additional intracoronary thrombolysis therapy. Although both thrombolytic therapies were effective, IVCT required more time than intracoronary thrombolysis to resolve the thrombus. We concluded that IVCT can be used as the first-line thrombolytic therapy for KD, except in cases with acute myocardial infarction.
authors.affiliation: Pediatrics and Adolescent Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.
authors.forename: Mana
authors.initials: M
authors.lastname: Harada
authors.forename: Katsumi
authors.initials: K
authors.lastname: Akimoto
authors.forename: Masao
authors.initials: M
authors.lastname: Otaka
authors.forename: Keiko
authors.initials: K
authors.lastname: Sato
authors.forename: Hisayuki
authors.initials: H
authors.lastname: Oda
authors.forename: Masahiro
authors.initials: M
authors.lastname: Otsuki
authors.forename: Ken
authors.initials: K
authors.lastname: Takahashi
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kishiro
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Shimizu
mesh_terms: D003323:Coronary Aneurysm / Q000150:complications* / Q000188:drug therapy; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D004452:Echocardiography; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications* / Q000188:drug therapy; D012189:Retrospective Studies; D015912:Thrombolytic Therapy / Q000379:methods*
chemical_list: D005343:Fibrinolytic Agents
keywords: Kawasaki disease; acute myocardial infarction; intracoronary thrombolysis; intravenous coronary thrombolysis; tissue polypeptide antigen