title: Urinary dysfunction with detrusor hyperactivity in women with Parkinson's disease cannot be blamed as a factor of worsening motor performance.
abstract: BACKGROUND
  Detrusor hyperactivity is the leading cause of urinary dysfunction in Parkinson's disease (PD). There are few studies correlating PD clinical aspects with this autonomic feature.
  
  
  METHODS
  A cohort of 63 women with PD were prospectively examined for assessment of clinical aspects and disease severity using unified Parkinson's disease rating scale and Hoehn-Yahr scale, respectively. The urologic function was evaluated by the urodynamic study. Two groups were categorized at this time - groups with and without detrusor hyperactivity. After seven years, the same parameters were re-evaluated.
  
  
  RESULTS
  Progression of the disease on mental scores was found in the group with detrusor hyperactivity. On follow-up, clinical symptoms and severity did not show significant worsening between the groups.
  
  
  CONCLUSIONS
  Detrusor hyperactivity is a frequent urodynamic finding in PD, and even though it is associated with dopaminergic dysfunction, it cannot be blamed as a factor of worsening motor performance, but is probably associated with poor cognitive and mental prognosis.
authors.affiliation: Movement Disorders Unit, Department of Neurology, Universidade Federal do Piauí, TeresinaPI, Brazil.
authors.forename: Raimundo Nonato
authors.initials: RN
authors.lastname: Campos-Sousa
authors.forename: Elizabeth Maria Aparecida Barasnevicius
authors.initials: EM
authors.lastname: Quagliato
authors.forename: Kelson James
authors.initials: KJ
authors.lastname: Almeida
authors.forename: Inácio Augusto Dias de
authors.initials: IA
authors.lastname: Castro
authors.forename: Viriato
authors.initials: V
authors.lastname: Campelo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D018450:Disease Progression; D005260:Female; D006801:Humans; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000503:physiopathology; D011379:Prognosis; D011446:Prospective Studies; D011597:Psychomotor Performance; D012720:Severity of Illness Index; D053201:Urinary Bladder, Overactive / Q000150:complications*; D014555:Urination Disorders / Q000209:etiology*