title: Is being female a risk factor for shallow anterior chamber? The associations between anterior chamber depth and age, sex, and body height.
abstract: OBJECTIVE
  To analyze the association between anterior chamber depth (ACD) and age, sex, and body height (BH).
  
  
  METHODS
  One thousand four hundred eighty eyes of 1480 adults 40 years of age and older receiving preoperative evaluation for cataract surgery were recruited consecutively from June 1, 2006, to December 31, 2010. ACD was measured with the Zeiss IOLMaster. Univariate and multivariate linear regression models were used to analyze the correlations, and receiving operator characteristic (ROC) curves and the area under the curve (AUC) were used for evaluating the predictability of an ACD less than 2.70 mm.
  
  
  RESULTS
  ACD was negatively correlated with age and positively correlated with BH in both univariate and multivariate regression analysis (P < 0.001). Sex was associated with ACD in univariate analysis, but not after adjustment with age and BH. In predicting an ACD less than 2.70 mm, the AUCs of ROC curves for 'age and sex', 'age and BH', and 'age, sex, and BH' were 0.687, 0.689, and 0.689, respectively.
  
  
  CONCLUSIONS
  Age and BH were independent associating factors of ACD; however, sex was not. Older people and shorter ones likely had shallower ACD, and therefore were predisposed to Primary angle closure glaucoma (PACG). The predictability of ACD by age and BH solely was low, and adding sex did not increase it.
authors.forename: Wei-Cherng
authors.initials: WC
authors.lastname: Hsu
authors.forename: Elizabeth P
authors.initials: EP
authors.lastname: Shen
authors.affiliation: Department of Ophthalmology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei; School of Medicine, Tzu Chi University, Hualien; National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Yi-Ting
authors.initials: YT
authors.lastname: Hsieh
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000867:Anterior Chamber / Q000473:pathology*; D001827:Body Height; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012372:ROC Curve; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D013624:Taiwan / Q000453:epidemiology; D041623:Tomography, Optical Coherence / Q000379:methods*