title: Clinical evolution of mediastinitis in patients undergoing adjuvant hyperbaric oxygen therapy after coronary artery bypass surgery.
abstract: OBJECTIVE
  To evaluate the use of hyperbaric oxygen therapy as an adjunctive treatment in mediastinitis after coronary artery bypass surgery.
  
  
  METHODS
  This is a retrospective descriptive study, performed between October 2010 and February 2012. Hyperbaric oxygen therapy was indicated in difficult clinical management cases despite antibiotic therapy.
  
  
  RESULTS
  We identified 18 patients with mediastinitis during the study period. Thirty three microorganisms were isolated, and polymicrobial infection was present in 11 cases. Enterobacteriaceae were the most prevalent pathogens and six were multi-resistant agents. There was only 1 hospital death, 7 months after the oxygen therapy caused by sepsis, unrelated to hyperbaric oxygen therapy. This treatment was well-tolerated.
  
  
  CONCLUSIONS
  The initial data showed favorable clinical outcomes.
authors.forename: Julyana Galvão Tabosa do
authors.initials: JG
authors.lastname: Egito
authors.forename: Cely Saad
authors.initials: CS
authors.lastname: Abboud
authors.forename: Aline Pâmela Vieira de
authors.initials: AP
authors.lastname: Oliveira
authors.forename: Carlos Alberto Gonçalves
authors.initials: CA
authors.lastname: Máximo
authors.forename: Carolina Moreira
authors.initials: CM
authors.lastname: Montenegro
authors.forename: Vivian Lerner
authors.initials: VL
authors.lastname: Amato
authors.forename: Roberto
authors.initials: R
authors.lastname: Bammann
authors.forename: Pedro Silvio
authors.initials: PS
authors.lastname: Farsky
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy / Q000379:methods; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008480:Mediastinitis / Q000209:etiology / Q000628:therapy*; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents