title: Heparin-induced thrombocytopenia causing graft thrombosis and bowel ischemia postendovascular aneurysm repair.
abstract: Heparin-induced thrombocytopenia (HIT) is an immune-mediated thrombocytopenia resulting from prior heparin exposure. It can be associated with limb- or life-threatening thrombotic events. Patients undergoing any vascular procedures including endovascular procedures that require heparin administration are at risk. There is very little reported in the literature with regards to thrombosis associated with HIT after endovascular aortic aneurysm repair. All reported cases of HIT thrombosis presented as acute arterial lower limb ischemia or deep vein thrombosis. In this report, we present a case of HIT complicated by stent graft thrombosis and bowel ischemia.
authors.affiliation: Division of Vascular Surgery, McGill University, McGill University Heath Centre, Royal Victoria Hospital, Montreal, Quebec, Canada.
authors.forename: Abdulmajeed
authors.initials: A
authors.lastname: Altoijry
authors.affiliation: Division of Vascular Surgery, McGill University, McGill University Heath Centre, Royal Victoria Hospital, Montreal, Quebec, Canada.
authors.forename: Kent S
authors.initials: KS
authors.lastname: MacKenzie
authors.affiliation: Division of Vascular Surgery, McGill University, McGill University Heath Centre, Royal Victoria Hospital, Montreal, Quebec, Canada.
authors.forename: Marc-Michel
authors.initials: MM
authors.lastname: Corriveau
authors.affiliation: Division of Vascular Surgery, McGill University, McGill University Heath Centre, Royal Victoria Hospital, Montreal, Quebec, Canada.
authors.forename: Daniel I
authors.initials: DI
authors.lastname: Obrand
authors.affiliation: Division of Vascular Surgery, McGill University, McGill University Heath Centre, Royal Victoria Hospital, Montreal, Quebec, Canada.
authors.forename: Cherrie Z
authors.initials: CZ
authors.lastname: Abraham
authors.affiliation: Division of Vascular Surgery, McGill University, McGill University Heath Centre, Royal Victoria Hospital, Montreal, Quebec, Canada. Electronic address: oren.steinmetz@muhc.mcgill.ca.
authors.forename: Oren K
authors.initials: OK
authors.lastname: Steinmetz
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D017544:Aortic Aneurysm, Abdominal / Q000175:diagnosis / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D057915:Drug Substitution; D057510:Endovascular Procedures / Q000009:adverse effects*; D006083:Graft Occlusion, Vascular / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D065666:Mesenteric Ischemia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D013921:Thrombocytopenia / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D006493:Heparin