title: A copper(I)-catalyzed three-component domino process: assembly of complex 1,2,3-triazolyl-5-phosphonates from azides, alkynes, and H-phosphates.
abstract: Three is better than one! A new copper-catalyzed tricomponent reaction of a terminal alkyne, organic azide, and H-phosphate (CuAA[P]C) leads to a structurally diverse polysubstituted 1,2,3-triazolyl-5-phosphonate, which provides an efficient tool for the direct introduction of phosphonic acid groups by a "click reaction".
authors.affiliation: Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007 (P. R. China), Fax: (+86) 3733325250. lingjunlee@htu.cn.
authors.forename: Lingjun
authors.initials: L
authors.lastname: Li
authors.forename: Guoliang
authors.initials: G
authors.lastname: Hao
authors.forename: Anlian
authors.initials: A
authors.lastname: Zhu
authors.forename: Xincui
authors.initials: X
authors.lastname: Fan
authors.forename: Guisheng
authors.initials: G
authors.lastname: Zhang
authors.forename: Lihe
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry; D063065:Organophosphonates / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction; D010710:Phosphates / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry
chemical_list: D000480:Alkynes; D001386:Azides; D063065:Organophosphonates; D010710:Phosphates; D014230:Triazoles; D003300:Copper; D006859:Hydrogen
keywords: alkynes; azides; catalysis; copper; multicomponent reactions