title: Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity.
abstract: The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity.
authors.affiliation: Faculdade de Química, Universidade Federal do Pará, BelémPA, Brasil.
authors.forename: Eduardo A A
authors.initials: EA
authors.lastname: Pinheiro
authors.affiliation: Faculdade de Química, Universidade Federal do Pará, BelémPA, Brasil.
authors.forename: Josiwander M
authors.initials: JM
authors.lastname: Carvalho
authors.affiliation: Faculdade de Química, Universidade Federal do Pará, BelémPA, Brasil.
authors.forename: Diellem C P dos
authors.initials: DC
authors.lastname: Santos
authors.affiliation: Faculdade de Química, Universidade Federal do Pará, BelémPA, Brasil.
authors.forename: André O
authors.initials: AO
authors.lastname: Feitosa
authors.affiliation: Faculdade de Química, Universidade Federal do Pará, BelémPA, Brasil.
authors.forename: Patrícia S B
authors.initials: PS
authors.lastname: Marinho
authors.affiliation: Faculdade de Química, Universidade Federal do Pará, BelémPA, Brasil.
authors.forename: Giselle Maria S P
authors.initials: GM
authors.lastname: Guilhon
authors.affiliation: Faculdade de Química, Universidade Federal do Pará, BelémPA, Brasil.
authors.forename: Lourivaldo S
authors.initials: LS
authors.lastname: Santos
authors.affiliation: Departamento de Química, Universidade Federal do Amazonas, ManausAM, Brasil.
authors.forename: Afonso L D de
authors.initials: AL
authors.lastname: Souza
authors.affiliation: Faculdade de Química, Universidade Federal do Pará, BelémPA, Brasil.
authors.forename: Andrey M R
authors.initials: AM
authors.lastname: Marinho
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001230:Aspergillus / Q000737:chemistry*; D036481:Bauhinia / Q000382:microbiology*; D008401:Gas Chromatography-Mass Spectrometry; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents