title: The association between bone mineral density and periodontitis in Korean adults (KNHANES 2008-2010).
abstract: OBJECTIVE
  This study investigated the association between bone mineral density (BMD) and periodontitis in a representative sample of Korean adults.
  
  
  METHODS
  Of 36 188 individuals who participated in the Korea National Health and Nutrition Examination Survey in 2008, 2009, and 2010, 9977 participants aged ≥40 years were included in this cross-sectional study. The associations of BMD of lumbar spine, total femur, and femoral neck with periodontitis were investigated using logistic regression analysis. Additionally, dose-response relationships with BMD divided into quintiles and the association between osteoporosis and periodontitis were investigated.
  
  
  RESULTS
  With the set of Community Periodontal Index (CPI) ≥ 3 as a dependent variable, logistic regression analysis revealed that a decrease of BMD was significantly associated with higher odds of periodontitis [range of adjusted odds ratios (AORs); 1.15-1.20, P < 0.001 for all BMD sites]. Similarly, these associations were also found in the CPI 4 model. With regard to dose-response relations, the lower the BMD quintile, the higher the AORs appeared with statistical significance in the CPI ≥ 3 model. (P for trend < 0.001) Participants with osteoporosis had 2.26 and 1.91 times higher odds for CPI ≥ 3 and CPI 4, respectively, than those with normal BMD, indicating a significant association between the two diseases.
  
  
  CONCLUSIONS
  Our results suggest that BMD is significantly associated with periodontitis.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Ewha Womans University, Seoul, Korea.
authors.forename: J W
authors.initials: JW
authors.lastname: Kim
authors.forename: K A
authors.initials: KA
authors.lastname: Kong
authors.forename: H Y
authors.initials: HY
authors.lastname: Kim
authors.forename: H S
authors.initials: HS
authors.lastname: Lee
authors.forename: S J
authors.initials: SJ
authors.lastname: Kim
authors.forename: S H
authors.initials: SH
authors.lastname: Lee
authors.forename: K W
authors.initials: KW
authors.lastname: Sim
authors.forename: M R
authors.initials: MR
authors.lastname: Kim
authors.forename: J H
authors.initials: JH
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D015519:Bone Density; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D010024:Osteoporosis / Q000453:epidemiology* / Q000503:physiopathology; D010512:Periodontal Index; D010518:Periodontitis / Q000453:epidemiology*; D056910:Republic of Korea / Q000453:epidemiology
keywords: Community Periodontal Index; National Health and Nutrition Examination Survey; bone mineral density; osteopenia; osteoporosis; periodontitis