title: The effect of the severity of liver cirrhosis on the level of lipids  and lipoproteins.
abstract: The effect of severity of liver cirrhosis, an alcoholic and non-alcoholic genesis, on the results of serum lipids and lipoproteins was evaluated. Serum cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-Ch), and low-density lipoprotein cholesterol (LDL-Ch) were measured in the sera of 59 patients suffering from alcoholic cirrhosis and 34 patients with non-alcoholic cirrhosis. The level of serum triglycerides depends on the severity of liver damage in alcoholic liver cirrhosis, being the highest in Child-Pugh score B. The severity of liver damage significantly affects the HDL-Ch and LDL-Ch levels in cirrhosis of non-alcoholic origin, reaching the highest value for LDL-Ch and the lowest for HDL-Ch in score C. It should not be generalized that the levels of lipids and lipoproteins in liver cirrhosis progressively diminished with the deterioration of liver function. The serum HDL-Ch and LDL-Ch may be considered as markers of severity of liver damage in non-alcoholic cirrhosis, but the triglycerides only in disease of alcoholic origin.
authors.forename: Lech
authors.initials: L
authors.lastname: Chrostek
authors.forename: Lukasz
authors.initials: L
authors.lastname: Supronowicz
authors.forename: Anatol
authors.initials: A
authors.lastname: Panasiuk
authors.forename: Bogdan
authors.initials: B
authors.lastname: Cylwik
authors.forename: Ewa
authors.initials: E
authors.lastname: Gruszewska
authors.forename: Robert
authors.initials: R
authors.lastname: Flisiak
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008103:Liver Cirrhosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D055815:Young Adult
chemical_list: D015415:Biomarkers; D008055:Lipids; D008074:Lipoproteins