title: Antioxidant properties of 3-deoxyanthocyanidins and polyphenolic extracts from Côte d'Ivoire's red and white sorghums assessed by ORAC and in vitro LDL oxidisability tests.
abstract: Red sorghum is a source of phenolic compounds (PCs), including 3-deoxyanthocyanidins that may protect against oxidative stress related disease such as atherosclerosis. HPLC was used to characterise and quantify PCs extracted from red or white sorghum whole grain flour. Antioxidant activity was measured by an oxygen radical absorbance capacity assay and against LDL-oxidisability, and further compared to that of synthesised 3-deoxyanthocyanidins (i.e., luteolinidin and apigeninidin). Phenolic content of red and white sorghums was evaluated as 3.90 ± 0.01 and 0.07 ± 0.01 mmol gallic acid equivalents L(-1), respectively. Luteolinidin and apigeninidin were mainly found in red sorghum. Red sorghum had almost 3 and 10 times greater specific antioxidant activity compared to luteolinidin and apigeninidin, respectively. Red sorghum PCs and the two 3-deoxyanthocyanidins were also effective at preventing LDL vitamin E depletion and conjugated diene production. Red sorghum flour exhibits antioxidant capacity suggesting that it may be a valuable health-promoting food.
authors.affiliation: UMR 204 NUTRIPASS, University Institute of Clinical Research, 641, Av. Doyen Gaston Giraud, 34093 Montpellier Cedex 5, France. Electronic address: marie-annette.carbonneau@univ-montp1.fr.
authors.forename: Marie-Annette
authors.initials: MA
authors.lastname: Carbonneau
authors.forename: Moctar
authors.initials: M
authors.lastname: Cisse
authors.forename: Nathalie
authors.initials: N
authors.lastname: Mora-Soumille
authors.forename: Sofiane
authors.initials: S
authors.lastname: Dairi
authors.forename: Maxence
authors.initials: M
authors.lastname: Rosa
authors.forename: Françoise
authors.initials: F
authors.lastname: Michel
authors.forename: Céline
authors.initials: C
authors.lastname: Lauret
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Cristol
authors.forename: Olivier
authors.initials: O
authors.lastname: Dangles
mesh_terms: D000872:Anthocyanins / Q000737:chemistry* / Q000302:isolation & purification; D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification; D047310:Apigenin / Q000737:chemistry / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid; D007560:Cote d'Ivoire; D006801:Humans; D008077:Lipoproteins, LDL / Q000737:chemistry; D010084:Oxidation-Reduction; D010936:Plant Extracts / Q000737:chemistry*; D059808:Polyphenols / Q000737:chemistry* / Q000302:isolation & purification; D017382:Reactive Oxygen Species / Q000737:chemistry; D045868:Sorghum / Q000737:chemistry* / Q000378:metabolism; D000094162:Phytoalexins
chemical_list: D000872:Anthocyanins; D000975:Antioxidants; D047310:Apigenin; D008077:Lipoproteins, LDL; D010936:Plant Extracts; D059808:Polyphenols; D017382:Reactive Oxygen Species; C099252:oxidized low density lipoprotein; C104027:apigeninidin; D000094162:Phytoalexins; C518537:luteolinidin
keywords: 3-Deoxyanthocyanidins, apigeninidin, luteolinidin; Low density lipoprotein oxidation; Oxygen radical absorption capacity; Sorghum polyphenols; Vitamin E