title: An element of life: competition for zinc in host-pathogen interaction.
abstract: Zinc homeostasis plays a plethora of different roles in the immune response. In this issue of Immunity, Vignesh et al. (2013) demonstrate that stimulation of macrophages with GM-CSF deprives intracellular Histoplasma capsulatum of zinc, improving pathogen clearance.
authors.affiliation: Institute of Immunology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany. Electronic address: hhaase@ukaachen.de.
authors.forename: Hajo
authors.initials: H
authors.lastname: Haase
mesh_terms: D000818:Animals; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000494:pharmacology*; D006658:Histoplasma / Q000276:immunology*; D006660:Histoplasmosis / Q000378:metabolism*; D006801:Humans; D017737:Macrophages, Peritoneal / Q000276:immunology*; D013481:Superoxides / Q000378:metabolism*; D015032:Zinc / Q000378:metabolism*
chemical_list: D013481:Superoxides; D016178:Granulocyte-Macrophage Colony-Stimulating Factor; D015032:Zinc