title: Benign infantile convulsions associated with mild gastroenteritis: an electroclinical study of 34 patients.
abstract: OBJECTIVE
  To analyze the electroclinical features and evolution of patients diagnosed with convulsions with mild gastroenteritis (CwG) from southwest China.
  
  
  METHODS
  We reviewed and analyzed the medical records of 34 patients (13 males) diagnosed with CwG and followed-up for at least 12 months.
  
  
  RESULTS
  The age of onset was 6-29 months and the female/male ratio 1.62. Seizures were generalized in 32 cases. Single seizures in 15 cases were <5 min and multiple seizures 24-48 h after seizure onset were seen in 18 cases. Seizure duration was <1 min in 32.35%, between 1 and 5 min in 55.88%, and between 5 and 10 min in 8.82% of seizures. The average interval between the onset of gastroenteritis and seizures was 2.47 days. Rotavirus antigen was positive in stools in 26.47% of cases. During the acute phase, diazepam and phenobarbital as first-line treatment were effective in 25% and 83.33% of cases, respectively. Fourteen patients showed non-specific anomalies in the interictal electroencephalography. During 12-36 months follow-up, 33 cases showed normal psychomotor development and no seizures.
  
  
  CONCLUSIONS
  CwG occurred mostly in toddlers. During the acute phase, phenobarbital is more effective in controlling seizures. For a good prognosis, it is unnecessary to administrate long-term anticonvulsants.
authors.affiliation: Department of Neurology, Children's Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Tingsong
authors.initials: T
authors.lastname: Li
authors.affiliation: Department of Neurology, Children's Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Siqi
authors.initials: S
authors.lastname: Hong
authors.affiliation: Maternal and Child Health Hospital of Changshou District, Chongqing, China.
authors.forename: Xing
authors.initials: X
authors.lastname: Peng
authors.affiliation: Department of Neurology, Children's Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Min
authors.initials: M
authors.lastname: Cheng
authors.affiliation: Department of Neurology, Children's Hospital of Chongqing Medical University, Chongqing, China; Ministry of Education Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, China. Electronic address: neurojiang@gmail.com.
authors.forename: Li
authors.initials: L
authors.lastname: Jiang
mesh_terms: D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004569:Electroencephalography / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D005759:Gastroenteritis / Q000175:diagnosis* / Q000453:epidemiology* / Q000503:physiopathology; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D012640:Seizures / Q000175:diagnosis* / Q000453:epidemiology* / Q000503:physiopathology
keywords: AEDs; Benign convulsions; CSF; CwG; EEG; Electroclinical features; Enteroteritis; ILAE; International League Against Epilepsy; anti-epilepticus drugs; benign convulsions associated with mild gastroenteritis; cerebrospinal fluid; electroencephalography