title: Preserved renal function after percutaneous radiofrequency ablation for renal tumors: experience of a single institution.
abstract: BACKGROUND
  Percutaneous radiofrequency ablation (RFA) for small renal tumors has been reported to be effective in patients with poor surgical status. We retrospectively analyzed clinical outcomes, including renal function, after RFA.
  
  
  METHODS
  We retrospectively analyzed data of 24 patients with small renal tumors treated by RFA in our institution from January 2007 to November 2012.
  
  
  RESULTS
  A total of 36 tumors (35 renal cell carcinomas and one colon cancer metastasis) with a mean diameter of 21.1 mm (10-45 mm) in 24 patients were treated. Complete ablation was achieved in 22 patients (91.7%). There were two recurrences in other sites of the kidney (8.3%) and two distant metastases (8.3%) during the mean follow-up period of 21 months (1-57 months). No severe perioperative complications were observed. No significant difference in serum creatinine levels before and after RFA procedures in the 22 evaluable patients, nor in seven patients with a solitary kidney.
  
  
  CONCLUSIONS
  RFA for small renal tumors is a safe treatment with sufficient preservation of renal function, even in patients with a solitary kidney.
authors.affiliation: Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, 13-1 Takaramachi, Kanazawa, Ishikawa, Japan, 920-8640. yasukita@med.kanazawa-u.ac.jp.
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Ofude
authors.forename: Yasuhide
authors.initials: Y
authors.lastname: Kitagawa
authors.forename: Wataru
authors.initials: W
authors.lastname: Koda
authors.forename: Satoru
authors.initials: S
authors.lastname: Ueno
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Kadono
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Konaka
authors.forename: Atsushi
authors.initials: A
authors.lastname: Mizokami
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Gabata
authors.forename: Mikio
authors.initials: M
authors.lastname: Namiki
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000601:surgery*; D017115:Catheter Ablation; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D007668:Kidney / Q000503:physiopathology* / Q000601:surgery; D007680:Kidney Neoplasms / Q000097:blood / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D003404:Creatinine
keywords: Renal tumor; percutaneous radiofrequency ablation; renal function