title: Pattern of intraocular pressure fluctuation in uveitic eyes treated with corticosteroids.
abstract: OBJECTIVE
  To determine IOP fluctuation in uveitic eyes treated with corticosteroids.
  
  
  METHODS
  Prospective Observational Study.
  
  
  METHODS
  Study of 116 consecutive new uveitis patients visiting Uveitis clinic, BPKLCOS. IOP was meticulously monitored. Data was analyzed in SPSS-16 using paired samples 't-test'.
  
  
  RESULTS
  The mean IOP in all patients at presentation, at 1 week, 3 weeks and 6 weeks were respectively 14.66 mmHg, 14.72 mmHg, 14.75 mmHg and 14.93 mmHg. This progressive IOP rise was not statistically significant. Ocular hypertension was seen in 20% eyes; 64.5% were due to corticosteroids. Steroid-induced ocular hypertension was seen in 37.03% of oral group, 14.28% of posterior subtenon group, 8.57% of topical group. Antiglaucoma medications were started in 61.2% of the cases with raised IOP. None had to undergo glaucoma filtering surgery.
  
  
  CONCLUSIONS
  Incidence of ocular hypertension in uveitic eyes was 20% in this study. Majority of them was corticosteroid induced. Timely medical treatment averted the necessity of surgical intervention for IOP control.
authors.affiliation: BP Koirala Lions Centre for Ophthalmic Studies, Maharajgunj , Kathmandu , Nepal.
authors.forename: Sneha
authors.initials: S
authors.lastname: Shrestha
authors.forename: Madhu
authors.initials: M
authors.lastname: Thapa
authors.forename: Dev Narayan
authors.initials: DN
authors.lastname: Shah
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D015994:Incidence; D007429:Intraocular Pressure / Q000187:drug effects / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009390:Nepal / Q000453:epidemiology; D009798:Ocular Hypertension / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D011446:Prospective Studies; D012307:Risk Factors; D014605:Uveitis / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D055815:Young Adult
chemical_list: D005938:Glucocorticoids