title: Proteinuria: Tubular handling of albumin-degradation or salvation?
abstract: In a recent study using transgenic mice with inducible podocyte-specific expression of tagged albumin, Tenten and colleagues report transtubular transport of albumin, possibly mediated by the neonatal Fc receptor. This study raises several questions about the physiological importance of this potential pathway and the implications for albuminuria in renal disease.
authors.affiliation: Department of Biomedicine, Aarhus University, Wilhelm Meyers Allé 3, DK-8000 Aarhus C, Denmark.
authors.forename: Erik I
authors.initials: EI
authors.lastname: Christensen
authors.forename: Henrik
authors.initials: H
authors.lastname: Birn
mesh_terms: D000419:Albuminuria / Q000378:metabolism*; D000818:Animals; D006801:Humans; D007687:Kidney Tubules, Proximal / Q000378:metabolism*; D008954:Models, Biological; D012709:Serum Albumin / Q000378:metabolism*; D057900:Transcytosis / Q000502:physiology*
chemical_list: D012709:Serum Albumin