title: Cervical pregnancy: a report of four cases.
abstract: Various conservative treatments for cervical pregnancy have been reported. However, unlike tubal ectopic pregnancy, the treatment of cervical pregnancy has not been well established. For patients who desire fertility preservation, treatment with methotrexate chemotherapy carries a high success rate for preservation of the uterus. When methotrexate is injected i.v. or i.m., expulsion of pregnant tissue occasionally takes up to 1 month. In this report, we present four cases of cervical pregnancy which were successfully managed by methotrexate injection into the bilateral uterine arteries. In cases presenting with massive bleeding, embolization of the bilateral uterine arteries was performed. Cervical pregnancy was aborted within 8 days safely, and fertility could be preserved without harmful side-effects.
authors.affiliation: Department of Obstetrics and Gynecology, Kurobe City Hospital, Toyama, Japan.
authors.forename: Keiko
authors.initials: K
authors.lastname: Kochi
authors.forename: Takao
authors.initials: T
authors.lastname: Hidaka
authors.forename: Kuniaki
authors.initials: K
authors.lastname: Yasoshima
authors.forename: Kenji
authors.initials: K
authors.lastname: Yoneda
authors.forename: Kazunori
authors.initials: K
authors.lastname: Arai
authors.forename: Takashi
authors.initials: T
authors.lastname: Arai
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage*; D000293:Adolescent; D000328:Adult; D005260:Female; D059247:Fertility Preservation; D006801:Humans; D007269:Injections, Intra-Arterial; D008727:Methotrexate / Q000008:administration & dosage*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy*; D055988:Uterine Artery; D002577:Uterine Cervical Diseases / Q000188:drug therapy*
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate
keywords: cervical pregnancy; chemotherapy; ectopic pregnancy; intra-arterial injection; methotrexate