title: [Pressure support ventilation and proportional assist ventilation during weaning from mechanical ventilation].
abstract: OBJECTIVE
  To compare tolerance, duration of mechanical ventilation (MV) and clinical outcomes during weaning from MV in patients subjected to either pressure support ventilation (PSV) or proportional assist ventilation (PAV).
  
  
  METHODS
  A prospective, observational study was carried out.
  
  
  METHODS
  Intensive Care Unit.
  
  
  METHODS
  A total of 40 consecutive subjects were allocated to either the PSV or the PAV group until each group contained 20 patients. Patients were included in the study when they met the criteria to begin weaning and the attending physician decided to initiate the weaning process. The physician selected the modality and set the ventilatory parameters.
  
  
  METHODS
  None.
  
  
  METHODS
  Demographic data, respiratory mechanics, ventilatory parameters, duration of MV, and clinical outcomes (reintubation, tracheostomy, mortality).
  
  
  RESULTS
  Baseline characteristics were similar in both groups. No significant differences were observed between the PSV and PAV groups in terms of the total duration of MV (10 [5-18] vs. 9 [7-19] days; P=.85), reintubation (5 [31%] vs. 3 [19%]; P=.69), or mortality (4 [20%] vs. 5 [25%] deaths; P=1). Eight patients (40%) in the PSV group and 6 patients (30%) in the PAV group (P=.74) required a return to volume assist-control ventilation due to clinical deterioration.
  
  
  CONCLUSIONS
  Tolerance, duration of MV and clinical outcomes during weaning from mechanical ventilation were similar in PSV and PAV.
authors.affiliation: Servicio de Medicina Intensiva, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona (UAB), Barcelona, España; Servicio de Medicina Intensiva, Hospital Sant Joan de Reus, Reus, Tarragona, España. Electronic address: hermar0699@gmail.com.
authors.forename: H
authors.initials: H
authors.lastname: Aguirre-Bermeo
authors.affiliation: Servicio de Medicina Intensiva, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona (UAB), Barcelona, España; Anestesia e Rianimazione 3, Ospedale Niguarda Ca' Granda, Milán, Italia.
authors.forename: M
authors.initials: M
authors.lastname: Bottiroli
authors.affiliation: Servicio de Medicina Intensiva, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona (UAB), Barcelona, España; Servicio de Medicina Intensiva, Hospital Verge de la Cinta, Tortosa, Tarragona, España.
authors.forename: S
authors.initials: S
authors.lastname: Italiano
authors.affiliation: Servicio de Medicina Intensiva, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona (UAB), Barcelona, España; Servicio de Medicina Intensiva, Hospital Sant Joan de Reus, Reus, Tarragona, España.
authors.forename: F
authors.initials: F
authors.lastname: Roche-Campo
authors.affiliation: Servicio de Medicina Intensiva, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona (UAB), Barcelona, España.
authors.forename: J A
authors.initials: JA
authors.lastname: Santos
authors.affiliation: Servicio de Farmacología Clínica, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona (UAB), Barcelona, España.
authors.forename: M
authors.initials: M
authors.lastname: Alonso
authors.affiliation: Servicio de Medicina Intensiva, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona (UAB), Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Mancebo
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D059725:Interactive Ventilatory Support; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012121:Respiration, Artificial; D015300:Ventilator Weaning / Q000379:methods*
keywords: Pressure support ventilation; Proportional assist ventilation; Retirada de ventilación mecánica; Ventilación con presión de soporte; Ventilación proporcional asistida; Weaning from mechanical ventilation