title: Capsule-odometer: a concept to improve accurate lesion localisation.
abstract: In order to improve lesion localisation in small-bowel capsule endoscopy, a modified capsule design has been proposed incorporating localisation and - in theory - stabilization capabilities. The proposed design consists of a capsule fitted with protruding wheels attached to a spring-mechanism. This would act as a miniature odometer, leading to more accurate lesion localization information in relation to the onset of the investigation (spring expansion e.g., pyloric opening). Furthermore, this capsule could allow stabilization of the recorded video as any erratic, non-forward movement through the gut is minimised. Three-dimensional (3-D) printing technology was used to build a capsule prototype. Thereafter, miniature wheels were also 3-D printed and mounted on a spring which was attached to conventional capsule endoscopes for the purpose of this proof-of-concept experiment. In vitro and ex vivo experiments with porcine small-bowel are presented herein. Further experiments have been scheduled.
authors.affiliation: Alexandros Karargyris, National Library of Medicine, National Institutes of Health, Bethesda, MD 20814, United States.
authors.forename: Alexandros
authors.initials: A
authors.lastname: Karargyris
authors.forename: Anastasios
authors.initials: A
authors.lastname: Koulaouzidis
mesh_terms: D000818:Animals; D053705:Capsule Endoscopes; D053704:Capsule Endoscopy / Q000295:instrumentation*; D004867:Equipment Design; D005240:Feasibility Studies; D006801:Humans; D007421:Intestine, Small / Q000033:anatomy & histology*; D008422:Materials Testing; D008904:Miniaturization; D013552:Swine
keywords: Capsule endoscopy; Hardware; Localisation; Odometer; Software