title: Pleomorphic adenoma of the nasal septum.
abstract: BACKGROUND
  Pleomorphic adenoma is the most common benign tumour of the salivary glands. The major salivary glands are most commonly involved, or more rarely accessory salivary glands, especially the oral cavity. Other locations, such as the nasal cavity, paranasal sinuses or upper aerodigestive tract, are exceptional.
  
  
  METHODS
  A 26-year-old female presented with right-sided nasal obstruction. Radiology found a lesion involving the anterior third of the nasal septum. The patient underwent complete surgical resection of the tumour via an endonasal approach. Histological examination found a mixed cellular component (epithelial and myoepithelial) and mesenchymatous tissue with chondromyxoid stroma, enabling diagnosis of a typical pleomorphic adenoma.
  
  
  CONCLUSIONS
  Pleomorphic adenoma is exceptional in the nasal cavity, with only a few cases reported in the literature. Although benign, the risk of local recurrence, malignant transformation and metastasis requires close long-term follow-up.
authors.affiliation: Service ORL et chirurgie cervico-faciale, centre hospitalier intercommunal André-Grégoire, 56, boulevard de Boissière, 93130 Montreuil, France.
authors.forename: S
authors.initials: S
authors.lastname: Baron
authors.affiliation: Service ORL et chirurgie cervico-faciale, centre hospitalier intercommunal André-Grégoire, 56, boulevard de Boissière, 93130 Montreuil, France. Electronic address: v.koka@noos.fr.
authors.forename: V
authors.initials: V
authors.lastname: Koka
authors.affiliation: Service ORL et chirurgie cervico-faciale, centre hospitalier intercommunal André-Grégoire, 56, boulevard de Boissière, 93130 Montreuil, France.
authors.forename: P
authors.initials: P
authors.lastname: El Chater
authors.affiliation: Service de pathologie, groupe hospitalier intercommunal Le-Raincy-Montfermeil, 10, avenue du Général-Leclerc, 93370 Montfermeil, France.
authors.forename: J
authors.initials: J
authors.lastname: Cucherousset
authors.affiliation: Service ORL et chirurgie cervico-faciale, centre hospitalier intercommunal André-Grégoire, 56, boulevard de Boissière, 93130 Montreuil, France.
authors.forename: C
authors.initials: C
authors.lastname: Paoli
mesh_terms: D008949:Adenoma, Pleomorphic / Q000175:diagnosis / Q000601:surgery; D000328:Adult; D005260:Female; D006801:Humans; D009300:Nasal Septum; D009669:Nose Neoplasms / Q000175:diagnosis / Q000601:surgery
keywords: Benign tumor; Nasal cavity; Nasal septum; Pleomorphic adenoma; Salivary glands