title: Translational vitreous proteomics.
abstract: The vitreous is an extracellular matrix that is still poorly understood. Although many constituents and characteristics have been previously determined, there are many attributes still being discovered. Currently, using protein arrays, MS, and bioinformatics, the vitreous provides a wealth of knowledge regarding ocular diseases and potential targets for personalized therapeutics.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USA; Omics Laboratory, University of Iowa, Iowa City, IA, USA.
authors.forename: Vinit B
authors.initials: VB
authors.lastname: Mahajan
authors.forename: Jessica M
authors.initials: JM
authors.lastname: Skeie
mesh_terms: D019295:Computational Biology; D005109:Extracellular Matrix / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods; D057285:Precision Medicine; D040081:Protein Array Analysis; D040901:Proteomics; D014822:Vitreous Body / Q000378:metabolism*
keywords: Retina; Vitrectomy; Vitreoretinopathy; Vitreous