title: Early and late urodynamic assessment of the orthotopic N-shaped neobladder.
abstract: The present study aimed to report the urodynamic data from 46 male patients who underwent an orthotopic N-shaped neobladder replacement following a radical cystectomy during a 12-month period and to provide urodynamic evidence for the improvement of this technique. A total of 46 consecutive male patients underwent a radical cystectomy and orthotopic N-shaped neobladder substitution due to muscle-invasive bladder cancer. Uroflowmetry, cystometry and urethral pressure profilometry were analyzed at 3-12 months following the surgery. The mean pressure of the neobladders was <15 cm H2O at volumes of <400 ml and 22.4 cm H2O at 100% capacity at 6 months. The mean pressure of the contractions was <40 cm H2O at 6 months. The mean filling pressure following the surgery at 3 months was higher compared with that at 6 months. No difference was observed at the other time-points. When comparing the 9- and 12-month urodynamic characteristics, no significant changes were observed in the cystometric capacity. The mean post-void residual (PVR) urine volume was 58 ml. A mean voiding peak of 16.2 ml/sec was obtained using the Valsalva maneuver. The daytime continence rate was 90% at 12 months while the night-time continence rate was 60%.
authors.affiliation: Department of Urology, Qingdao Municipal Hospital, Qingdao, Shandong 266071, P.R. China ; School of Medicine, Shandong University, Jinan, Shandong 250012, P.R. China.
authors.forename: Zongliang
authors.initials: Z
authors.lastname: Zhang
authors.forename: Haiyan
authors.initials: H
authors.lastname: Qi
authors.forename: Rongxiang
authors.initials: R
authors.lastname: Zhou
authors.forename: Xunbo
authors.initials: X
authors.lastname: Jin
keywords: bladder neoplasms; bladder substitution; ileum; neobladder; radical cystectomy; urodynamics