title: Lack of association of IDH1, IDH2 and DNMT3A mutations with outcome in older patients with acute myeloid leukemia treated with hypomethylating agents.
authors.affiliation: Department of Leukemia, University of Texas M. D. Anderson Cancer Center , Houston, TX , USA.
authors.forename: Courtney D
authors.initials: CD
authors.lastname: DiNardo
authors.forename: Keyur P
authors.initials: KP
authors.lastname: Patel
authors.forename: Guillermo
authors.initials: G
authors.lastname: Garcia-Manero
authors.forename: Rajyalakshmi
authors.initials: R
authors.lastname: Luthra
authors.forename: Sherry
authors.initials: S
authors.lastname: Pierce
authors.forename: Gautam
authors.initials: G
authors.lastname: Borthakur
authors.forename: Elias
authors.initials: E
authors.lastname: Jabbour
authors.forename: Tapan
authors.initials: T
authors.lastname: Kadia
authors.forename: Naveen
authors.initials: N
authors.lastname: Pemmaraju
authors.forename: Marina
authors.initials: M
authors.lastname: Konopleva
authors.forename: Stefan
authors.initials: S
authors.lastname: Faderl
authors.forename: Jorge
authors.initials: J
authors.lastname: Cortes
authors.forename: Hagop M
authors.initials: HM
authors.lastname: Kantarjian
authors.forename: Farhad
authors.initials: F
authors.lastname: Ravandi
mesh_terms: D001374:Azacitidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D004248:DNA (Cytosine-5-)-Methyltransferases / Q000235:genetics*; D000090205:DNA Methyltransferase 3A; D000077209:Decitabine; D006801:Humans; D007521:Isocitrate Dehydrogenase / Q000235:genetics*; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000235:genetics* / Q000401:mortality; D009154:Mutation; D011379:Prognosis; D016896:Treatment Outcome
chemical_list: C000717967:DNMT3A protein, human; D000077209:Decitabine; C538784:IDH2 protein, human; D007521:Isocitrate Dehydrogenase; C543588:IDH1 protein, human; D004248:DNA (Cytosine-5-)-Methyltransferases; D000090205:DNA Methyltransferase 3A; D001374:Azacitidine