title: Molecular characterization of a catalase-negative methicillin-susceptible Staphylococcus aureus subsp. aureus strain collected from a patient with cutaneous abscess.
abstract: We describe a cutaneous abscess caused by catalase-negative methicillin-susceptible Staphylococcus aureus subsp. aureus in a patient who was concomitantly colonized with virulent USA300 methicillin-resistant S. aureus (MRSA). Sequencing of the katA gene demonstrated a thymine insertion leading to a frameshift mutation and premature truncation of catalase to 21 amino acids.
authors.affiliation: Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
authors.forename: Michael W
authors.initials: MW
authors.lastname: Ellis
authors.forename: Ryan C
authors.initials: RC
authors.lastname: Johnson
authors.forename: Katrina
authors.initials: K
authors.lastname: Crawford
authors.forename: Jeffrey B
authors.initials: JB
authors.lastname: Lanier
authors.forename: D Scott
authors.initials: DS
authors.lastname: Merrell
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000382:microbiology*; D002374:Catalase / Q000235:genetics*; D018389:Codon, Nonsense; D016368:Frameshift Mutation; D006801:Humans; D008297:Male; D017422:Sequence Analysis, DNA; D013207:Staphylococcal Skin Infections / Q000175:diagnosis* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000201:enzymology* / Q000302:isolation & purification*; D055815:Young Adult
chemical_list: D018389:Codon, Nonsense; D002374:Catalase