title: Nanoemulsions and nonwoven fabrics carrying AgNPs: antibacterial but may be cytotoxic.
abstract: Abstract The aim of this study is to prepare nonwoven fabrics carrying silver nanoparticles (AgNPs), and to investigate their antibacterial activities and cytotoxicities in parallel. AgNPs were impregnated from their nanoemulsions onto two commercially available nonwoven fabrics: pure-cotton fabrics (PCF) and polyester/viscous fabrics (PVF), by a simple adsorption (dipping) and were then heat stabilized. PCF exhibited stronger antibacterial effects on both Staphylococcus aureus and Escherichia coli. In-vitro cell culture studies demonstrated that AgNPs nanoemulsions and also fabrics carrying them were cytotoxic on L929-fibroblasts in all concentrations used here (6.25-400 ppm) in different extends. Only the fabrics loaded with AgNPs using nanoemulsion with the lowest concentration of 6.25 ppm exhibited low cytotoxicity but were still antibacterial.
authors.affiliation: Division of Nanotechnology and Nanomedicine, Hacettepe University , Ankara , Turkey.
authors.forename: Farzaneh
authors.initials: F
authors.lastname: Moghtader
authors.forename: Mojtaba
authors.initials: M
authors.lastname: Salouti
authors.forename: Mustafa
authors.initials: M
authors.lastname: Türk
authors.forename: Erhan
authors.initials: E
authors.lastname: Pişkin
mesh_terms: D000327:Adsorption; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D032561:Cotton Fiber; D004655:Emulsions / Q000737:chemistry / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects* / Q000502:physiology; D005347:Fibroblasts / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D051379:Mice; D049329:Nanostructures; D011091:Polyesters / Q000737:chemistry; D012834:Silver / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000502:physiology
chemical_list: D000900:Anti-Bacterial Agents; D004655:Emulsions; D011091:Polyesters; D012834:Silver
keywords: Antibacterial effects; Cytotoxicity; Nonwoven fabrics; Silver nanoparticles