title: [Pharmacotherapy for rheumatoid arthritis in the early 21st century: Russian and international experience].
abstract: The paper summarizes the data of international and Russian studies concerning current approaches to the pharmacotherapy of rheumatoid arthritis. Particular emphasis is placed on the substantiation of the treat-to-target concept, on the efficacy and safety of genetically engineered biological agents, including the inhibitors of tumor necrosis factor, interleukin-6 receptors, T-lymphocyte co-stimulation, and anti-B-cell therapy.
authors.forename: E L
authors.initials: EL
authors.lastname: Nasonov
authors.forename: D E
authors.initials: DE
authors.lastname: Karateev
authors.forename: G V
authors.initials: GV
authors.lastname: Lukina
mesh_terms: D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000266:history / Q000276:immunology; D049674:History, 21st Century; D006801:Humans; D007155:Immunologic Factors / Q000276:immunology / Q000627:therapeutic use*; D012219:Rheumatology / Q000266:history / Q000639:trends*; D012426:Russia
chemical_list: D007155:Immunologic Factors