title: Value of EQ-5D in Mexican city older population with and without dementia (SADEM study).
abstract: BACKGROUND
  The EuroQoL-5D (EQ-5D) is a brief, multi-attribute, preference-based health status measurement. The objective of this study was to assess the validity and reliability of EQ-5D in older adults with and without dementia in Mexico City.
  
  
  METHODS
  The Study on Aging and Dementia in Mexico (SADEM) was a survey of 3101, Mexican adults (60 + years old). An in-home face-to-face interview was administered. EQ-5D using ranking to rate states on a 100-point visual analogue scale; Daily Living Activities (ADL), Instrumental Activities of Daily Living (IADL), Mini Mental State Examination (MMSE), Short Form of the quality of life survey (SF-36), and Charlson comorbility index were used for comparison. The validity and reliability of EQ-5D were tested. We identified states of health for direct valuation; state 11111 ("no problems") had to be included because it was essential to the reseating (onto a 0-1 scale) of the visual analogue scale data. We included all plausible combinations of levels across each of the five EQ-5D dimensions and evaluated any significant interaction effects and factorial designs, based on balanced complete blocks.
  
  
  RESULTS
  The EQ-5D was applied to 3101 older people, of whom 109 (3.4%) had dementia. The general reliability of EQ-5D for cases was 0.80 and for controls 0.76, for each dimension. We had a total of 103 combinations for controls and 45 for cases. The percentage for the state of health "no problems" (11111) for controls was 30.4%, and had the highest percentage of cases (8.8%).
  
  
  CONCLUSIONS
  The resulting valuations form the basis for clinical use and facilitate the interpretation and evaluation of health care.
authors.affiliation: Neurological Diseases Research Unit, Specialty Hospital, National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico.
authors.forename: Rosalinda
authors.initials: R
authors.lastname: Sanchez-Arenas
authors.forename: Gilberto
authors.initials: G
authors.lastname: Vargas-Alarcon
authors.forename: Sergio
authors.initials: S
authors.lastname: Sanchez-Garcia
authors.forename: Carmen
authors.initials: C
authors.lastname: Garcia-Peña
authors.forename: Lidia
authors.initials: L
authors.lastname: Gutierrez-Gutierrez
authors.forename: Israel
authors.initials: I
authors.lastname: Grijalva
authors.forename: Angelica
authors.initials: A
authors.lastname: Garcia-Dominguez
authors.forename: Teresa
authors.initials: T
authors.lastname: Juárez-Cedillo
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D010054:Brief Psychiatric Rating Scale; D003704:Dementia / Q000175:diagnosis* / Q000523:psychology; D015577:Geriatric Assessment / Q000379:methods*; D006304:Health Status; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008800:Mexico; D008875:Middle Aged; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires / Q000592:standards*
keywords: aged; dementia; health state valuations; quality of life EQ-5D