title: Recent advances in organocatalytic methods for asymmetric C-C bond formation.
abstract: Beyond a doubt organocatalysis belongs to the most exciting and innovative chapters of organic chemistry today. Organocatalysis has emerged not only as a complement to metal-catalyzed reactions and to biocatalysis over the last decade, but also provides new asymmetric organocatalyzed reactions that cannot be accomplished by metal- or biocatalyzed reactions so far. A large number of organocatalytic processes are already well established in organic synthesis. Nevertheless, the number of publications in this field is still on the increase; new important results are produced constantly. This review gives a detailed overview of the latest developments and main streams in organocatalyzed asymmetric CC bond formation processes of the last three years. It is intended to outline the most important current findings focused on especially new synthetic methodologies.
authors.affiliation: Department of Chemistry, Humboldt-University Berlin, Brook-Taylor Strasse 2, 12489 Berlin (Germany).
authors.forename: Ulf
authors.initials: U
authors.lastname: Scheffler
authors.forename: Rainer
authors.initials: R
authors.lastname: Mahrwald
mesh_terms: D000215:Acylation; D000478:Alkylation; D001573:Benzoin / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D061565:Cycloaddition Reaction; D008670:Metals / Q000737:chemistry; D009930:Organic Chemicals / Q000737:chemistry*
chemical_list: D008670:Metals; D009930:Organic Chemicals; D002244:Carbon; D001573:Benzoin
keywords: CC bond formation; Michael addition; asymmetric synthesis; organocatalysis