title: [Advances in head and neck cancers on behalf of the French Intergroup ORL and GORTEC].
abstract: Head and neck cancers are the fifth among the most common cancers in France. Two thirds of cases occur at an advanced stage. For advanced disease, progression-free survival, despite undeniable progress, remains below 50% at three years. The last 20 years have been marked by the necessity to identify situations where less intense surgery and/or radiotherapy and/or chemotherapy is possible without jeopardizing the prognosis, and situations where a therapeutic intensification is necessary and results in a gain in survival while better preserving function with less toxicity. French cooperative groups gathering radiation oncologists (GORTEC), surgeons (GETTEC) and medical oncologists or physicians involved in the management of systemic treatments in head and neck cancers (GERCOR) are now belonging to the INCa-labelled Intergroup ORL to deal with the challenges of head and neck cancers.
authors.affiliation: Intergroupe ORL (GORTEC, GETTEC, GERCOR), Institut de Cancérologie de l'Ouest René-Gauducheau, boulevard Jacques-Monod, 44805 Saint-Herblain, France.
authors.forename: J
authors.initials: J
authors.lastname: Thariat
authors.forename: F
authors.initials: F
authors.lastname: Jegoux
authors.forename: Y
authors.initials: Y
authors.lastname: Pointreau
authors.forename: J
authors.initials: J
authors.lastname: Fayette
authors.forename: P
authors.initials: P
authors.lastname: Boisselier
authors.forename: P
authors.initials: P
authors.lastname: Blanchard
authors.forename: M
authors.initials: M
authors.lastname: Alfonsi
authors.forename: A
authors.initials: A
authors.lastname: Aupérin
authors.forename: E
authors.initials: E
authors.lastname: Bardet
authors.forename: R-J
authors.initials: RJ
authors.lastname: Bensadoun
authors.forename: P
authors.initials: P
authors.lastname: Garaud
authors.forename: L
authors.initials: L
authors.lastname: Geoffrois
authors.forename: P
authors.initials: P
authors.lastname: Graff
authors.forename: J
authors.initials: J
authors.lastname: Guigay
authors.forename: F
authors.initials: F
authors.lastname: Janot
authors.forename: M
authors.initials: M
authors.lastname: Lapeyre
authors.forename: J-L
authors.initials: JL
authors.lastname: Lefebvre
authors.forename: L
authors.initials: L
authors.lastname: Martin
authors.forename: S
authors.initials: S
authors.lastname: Racadot
authors.forename: F
authors.initials: F
authors.lastname: Rolland
authors.forename: C
authors.initials: C
authors.lastname: Sire
authors.forename: Y
authors.initials: Y
authors.lastname: Tao
authors.forename: C
authors.initials: C
authors.lastname: Tuchais
authors.forename: B
authors.initials: B
authors.lastname: Chibaudel
authors.forename: M-H
authors.initials: MH
authors.lastname: Girard-Calais
authors.forename: A
authors.initials: A
authors.lastname: Cornely
authors.forename: N
authors.initials: N
authors.lastname: Vintonenko
authors.forename: G
authors.initials: G
authors.lastname: Calais
authors.forename: D
authors.initials: D
authors.lastname: De Raucourt
authors.forename: J
authors.initials: J
authors.lastname: Lacau Saint-Guily
authors.forename: J
authors.initials: J
authors.lastname: Bourhis
mesh_terms: D059248:Chemoradiotherapy / Q000379:methods / Q000639:trends; D018572:Disease-Free Survival; D005602:France; D006801:Humans; D060828:Induction Chemotherapy / Q000379:methods; D054020:Lasers, Gas / Q000627:therapeutic use; D008495:Medical Oncology / Q000458:organization & administration; D059351:Organ Sparing Treatments / Q000379:methods; D010036:Otolaryngology / Q000379:methods / Q000458:organization & administration* / Q000639:trends; D010039:Otorhinolaryngologic Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy* / Q000821:virology; D030361:Papillomavirus Infections / Q000150:complications; D010255:Paranasal Sinus Neoplasms / Q000601:surgery; D010789:Phototherapy / Q000379:methods; D018787:Radiation Oncology / Q000379:methods / Q000458:organization & administration* / Q000639:trends; D019233:Retreatment / Q000379:methods; D012371:Robotics / Q000379:methods; D021701:Sentinel Lymph Node Biopsy
keywords: cancer; chemotherapy; head and neck; radiation therapy; surgery