title: Surgery for posterior vaginal wall prolapse.
abstract: OBJECTIVE
  The aim was to review the safety and efficacy of surgery for posterior vaginal wall prolapse.
  
  
  METHODS
  Every 4 years and as part of the Fifth International Collaboration on Incontinence we reviewed the English-language scientific literature after searching PubMed, Medline, Cochrane library and Cochrane database of systematic reviews, published up to January 2012. Publications were classified as level 1 evidence (randomised controlled trials [RCT] or systematic reviews), level 2 (poor quality RCT, prospective cohort studies), level 3 (case series or retrospective studies) and level 4 (case reports). The highest level of evidence was utilised by the committee to make evidence-based recommendations based upon the Oxford grading system. Grade A recommendation usually depends on consistent level 1 evidence. Grade B recommendation usually depends on consistent level 2 and/or 3 studies, or "majority evidence" from RCTs. Grade C recommendation usually depends on level 4 studies or "majority evidence from level 2/3 studies or Delphi processed expert opinion. Grade D "no recommendation possible" would be used where the evidence is inadequate or conflicting and when expert opinion is delivered without a formal analytical process, such as by Delphi.
  
  
  RESULTS
  Level 1 and 2 evidence suggest that midline plication posterior repair without levatorplasty might have superior objective outcomes compared with site-specific posterior reopair (grade B). Higher dyspareunia rates are reported when levatorplasty is employed (grade C). The transvaginal approach is superior to the transanal approach for repair of posterior wall prolapse (grade A). To date, no studies have shown any benefit of mesh overlay or augmentation of a suture repair for posterior vaginal wall prolapse (grade B). While modified abdominal sacrocolpopexy results have been reported, data on how these results would compare with traditional transvaginal repair of posterior vaginal wall prolapse are lacking.
  
  
  CONCLUSIONS
  Midline fascial plication without levatorplasty is the procedure of choice for posterior compartment prolapse. No evidence supports the use of polypropylene mesh or biological graft in posterior vaginal compartment prolapse surgery.
authors.affiliation: The Christ Hospital, Cincinnati, OH, USA.
authors.forename: Mickey
authors.initials: M
authors.lastname: Karram
authors.forename: Christopher
authors.initials: C
authors.lastname: Maher
mesh_terms: D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D056887:Pelvic Organ Prolapse / Q000473:pathology / Q000601:surgery*; D020047:Rectocele / Q000473:pathology / Q000601:surgery*; D014621:Vagina / Q000473:pathology