title: Histopathological findings of endometrial specimens in abnormal uterine bleeding.
abstract: OBJECTIVE
  The aim of this study was to assess the frequency of different histopathological findings obtained from dilatation and curettage (D&C) specimens in patients with abnormal uterine bleeding (AUB).
  
  
  METHODS
  In a retrospective review of 591 specimens, the included subjects were all women with AUB who underwent D&C between 2002 and 2006 in Be'sat Hospital, Tehran, Iran. The pathological diagnoses were analyzed in four groups from normal to malignant endometrium. The pathological groups were evaluated for patients' characteristics including demographic data and medical history.
  
  
  RESULTS
  The majority of patients (61.6%) were in the 41-50 year age group. Totally, 81.4% of patients had normal pathology. The disordered proliferative endometrium/polyps, hyperplasia, and malignant pathology were found in 15.4, 2.5, and 0.7% of specimens, respectively. The abnormal pathologies were seen more among patients with postmenopausal status, nulli-/primigravid women, and those with hypertension, diabetes, hypothyroidism, and polycystic ovary syndrome.
  
  
  CONCLUSIONS
  The proliferative endometrium and secretory endometrium were the most common histopathological observations in AUB patients in our region, and except normal endometrium, disordered proliferative endometrium was the most common cause of AUB.
authors.affiliation: Department of Pathology, Be'sat Hospital, AJA University of Medical Sciences, Basij Highway, Tehran, Iran.
authors.forename: Ebrahim
authors.initials: E
authors.lastname: Soleymani
authors.forename: Katayoun
authors.initials: K
authors.lastname: Ziari
authors.forename: Omid
authors.initials: O
authors.lastname: Rahmani
authors.forename: Masoomeh
authors.initials: M
authors.lastname: Dadpay
authors.forename: Maryam
authors.initials: M
authors.lastname: Taheri-Dolatabadi
authors.forename: Kamyab
authors.initials: K
authors.lastname: Alizadeh
authors.forename: Nahid
authors.initials: N
authors.lastname: Ghanbarzadeh
mesh_terms: D000328:Adult; D001706:Biopsy; D004107:Dilatation and Curettage / Q000009:adverse effects / Q000706:statistics & numerical data*; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D007492:Iran; D008875:Middle Aged; D011127:Polyps / Q000473:pathology*; D012189:Retrospective Studies; D012307:Risk Factors; D014592:Uterine Hemorrhage / Q000209:etiology / Q000473:pathology*