title: "Nocturnal seizures" in idiopathic pulmonary arterial hypertension.
abstract: The usual differential diagnoses of nocturnal events in children include parasomnias, nocturnal seizures, nocturnal reflux (Sandifer syndrome), hypnic jerks, periodic limb movements of sleep, and sleep disordered breathing. We report a previously healthy young girl who presented to the sleep clinic for evaluation of nocturnal events which were diagnosed as medically refractory nocturnal seizures. It was not until a syncopal event occurred in the daytime, which prompted referral for cardiac evaluation, the diagnosis of idiopathic pulmonary arterial hyper-tension (IPAH) was made. Sleep physicians should consider IPAH in the differential diagnosis of nocturnal events in children.
authors.affiliation: Sleep Disorders Center of New England, St. Vincent Hospital, Worcester, MA ; Center for Pediatric Sleep Disorders, Boston Children's Hospital, Harvard Medical School, Boston, MA.
authors.forename: Anthony
authors.initials: A
authors.lastname: Izzo
authors.forename: Julia
authors.initials: J
authors.lastname: McSweeney
authors.forename: Thomas
authors.initials: T
authors.lastname: Kulik
authors.forename: Umakanth
authors.initials: U
authors.lastname: Khatwa
authors.forename: Sanjeev V
authors.initials: SV
authors.lastname: Kothare
mesh_terms: D002243:Carbolines / Q000008:administration & dosage; D002303:Cardiac Output, Low; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D011464:Epoprostenol / Q000008:administration & dosage / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D010102:Oxygen Inhalation Therapy; D020447:Parasomnias / Q000150:complications / Q000175:diagnosis*; D012640:Seizures / Q000150:complications / Q000175:diagnosis*; D012720:Severity of Illness Index; D012891:Sleep Apnea Syndromes / Q000209:etiology / Q000503:physiopathology; D000068581:Tadalafil; D016896:Treatment Outcome; D014859:Warfarin / Q000008:administration & dosage
chemical_list: D002243:Carbolines; D014859:Warfarin; D000068581:Tadalafil; D011464:Epoprostenol; C427248:treprostinil
keywords: Nocturnal events; children; pulmonary hypertension; syncope