title: Polychlorinated biphenyls, polybrominated diphenyl ethers, and phthalates in roach from the Seine River basin (France): impact of densely urbanized areas.
abstract: Endocrine disruptors (EDs) from three chemical classes-polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), and phthalates-were investigated in the Seine River and one tributary, the Orge River, upstream and downstream of urban areas. The impact of urban areas was characterized by a concentration increase of all compounds in the Seine River and for phthalates and PBDEs in the Orge River. In the Seine River, from upstream (Marnay) to downstream (Triel) of urban areas, water concentration increases were greater for diethylhexyl phthalate (DEHP) (6 times, p < 0.05) and ∑tri-hexa BDE (5 times [p < 0.05]) than for ∑7PCBi (2.6 times). Simultaneously, sediments displayed a strong accumulation of contaminants downstream and compared with upstream values, their concentrations increased greatly: 202-fold for DEHP, 69-fold for BDE209, 25-fold for ∑tri-hexa-BDE, and 11-fold for ∑7PCBi. Variations of fish ED concentrations gave an indication of their habitat contamination increase observed downstream of densely urbanized areas of the Seine River, especially for PBDEs (∑tri-hexa-PBDEs = 14-fold increase ≤15.7 ± 6.9 ng g(-1) dry weight [dw; p < 0.001]) and for PCBs (∑7PCBi eightfold increase ≤211 ± 55 ng g(-1) dw [p < 0.01]). PCA results highlighted relationships between the different ED classes. A correlation (p < 0.05) was observed between PCB and PBDE fish concentrations, suggesting common sources and similar absorption mechanisms. For PCBs, which were poorly biodegraded, the bioaccumulation factor was strongly correlated (p < 0.001) to molecular hydrophobicity, whereas for PBDEs a negative correlation (p < 0.05) was observed related active debromination processes. This multichemical study investigates for the first time the occurrence of a wide range of EDs in roach, which was chosen as a sentinel species for this survey of surface water contamination.
authors.affiliation: Unité mixte de recherche-UMR 7619 SISYPHE, CNRS/Université Pierre et Marie Curie, Paris, France, marie-jeanne.teil@upmc.fr.
authors.forename: Marie-Jeanne
authors.initials: MJ
authors.lastname: Teil
authors.forename: Khawla
authors.initials: K
authors.lastname: Tlili
authors.forename: Martine
authors.initials: M
authors.lastname: Blanchard
authors.forename: Pierre
authors.initials: P
authors.lastname: Labadie
authors.forename: Fabrice
authors.initials: F
authors.lastname: Alliot
authors.forename: Marc
authors.initials: M
authors.lastname: Chevreuil
mesh_terms: D000818:Animals; D003530:Cyprinidae / Q000378:metabolism*; D004784:Environmental Monitoring; D005411:Flame Retardants / Q000378:metabolism; D005602:France; D055768:Halogenated Diphenyl Ethers / Q000378:metabolism*; D010795:Phthalic Acids / Q000378:metabolism*; D011078:Polychlorinated Biphenyls / Q000378:metabolism*; D045483:Rivers / Q000737:chemistry; D014507:Urbanization; D014874:Water Pollutants, Chemical / Q000378:metabolism*
chemical_list: D005411:Flame Retardants; D055768:Halogenated Diphenyl Ethers; D010795:Phthalic Acids; D014874:Water Pollutants, Chemical; C032279:phthalic acid; D011078:Polychlorinated Biphenyls