title: Silver-doped manganese dioxide and trioxide nanoparticles inhibit both gram positive and gram negative pathogenic bacteria.
abstract: Palladium, ruthenium and silver-doped MnO2 and silver doped Mn2O3 nanoparticles were synthesized by simple co-precipitation technique. SEM-TEM analysis revealed the nano-size of these synthesized samples. XPS data illustrates that Mn is present in 4+ and 3+ oxidation states in MnO2 and Mn2O3 respectively. Thermal analysis gave significant evidence for the phase changes with increasing temperature. Antibacterial activity of these synthesized nanoparticles on three Gram positive bacterial cultures (Staphylococcus aureus ATCC 6538, Streptococcus epidermis ATCC 12228, Bacillus subtilis ATCC 6633) and three Gram negative cultures (Escherichia coli ATCC 8739, Salmonella abony NCTC 6017 and Klebsiella pneumoniae ATCC 1003) was investigated using a disc diffusion method and live/dead assay. Only Ag-doped MnO2 and Ag-doped Mn2O3 nanoparticles showed antibacterial property against all six-test bacteria but Ag-doped MnO2 was found to be more effective than Ag-doped Mn2O3.
authors.affiliation: Department of Chemistry, Goa University, Goa 403206, India. Electronic address: kunkalekar.rohan@rediffmail.com.
authors.forename: R K
authors.initials: RK
authors.lastname: Kunkalekar
authors.affiliation: Department of Biological Sciences, Birla Institute of Technology and Science Pilani, K. K. Birla Goa Campus, Zuarinagar, Goa 403726, India.
authors.forename: M S
authors.initials: MS
authors.lastname: Prabhu
authors.affiliation: Department of Microbiology, Goa University, Goa 403206, India.
authors.forename: M M
authors.initials: MM
authors.lastname: Naik
authors.affiliation: Department of Chemistry, Goa University, Goa 403206, India.
authors.forename: A V
authors.initials: AV
authors.lastname: Salker
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D017895:Manganese Compounds / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D053758:Nanoparticles / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D017895:Manganese Compounds; D010087:Oxides; D012834:Silver; C016552:manganese dioxide
keywords: Antibacterial activity; Doped Mn(2)O(3); Doped MnO(2); Nanoparticles; Silver