title: Synovial sarcoma of the neck masquerading as a malignant second branchial cleft cyst.
abstract: Synovial sarcoma is an uncommon, aggressive malignant tumor of the soft tissues primarily involving the extremities of young adults. Head and neck synovial sarcoma is rare, and its diagnosis and therapy are still challenging.We report a case of a young patient with synovial sarcoma, clinically masquerading as cystic mass of the neck and malignant second branchial cleft cyst. The pathological diagnosis of the sarcoma was confirmed by a multimodality diagnostic protocol, including histological, immunohistochemical and molecular genetic analysis. The patient underwent complete surgical excision followed by postoperative radiotherapy and recovered well.
authors.affiliation: Department of Otorhinolaryngology, Hangzhou First People's Hospital Hangzhou, 310006, P.R. China.
authors.forename: Yao-Shu
authors.initials: YS
authors.lastname: Teng
authors.forename: Zhi-Hong
authors.initials: ZH
authors.lastname: Lin
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
authors.forename: Xiao-Lin
authors.initials: XL
authors.lastname: Cao
authors.forename: Feng-Chun
authors.initials: FC
authors.lastname: Lin
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Xiang
mesh_terms: D001935:Branchioma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008297:Male; D009333:Neck / Q000473:pathology* / Q000601:surgery; D013584:Sarcoma, Synovial / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult
keywords: Synovial sarcoma; branchial cleft cyst; head and neck; molecular genetic testing