title: Long-term safety and efficacy of low-dose clopidogrel in Japanese patients undergoing coronary stenting: a preliminary study.
abstract: This study evaluated long-term safety and efficacy of low-dose (50-mg) clopidogrel in Japanese patients undergoing coronary stenting. A total of 126 patients with 153 lesions who consented to take a 50-mg maintenance dose of clopidogrel to prevent stent thrombosis were enrolled. The duration of clinical follow-up was 13.9 ± 9.7 months. There was one early stent thrombosis (0.65%). Neither late nor very late stent thrombosis was observed in patients on clopidogrel plus aspirin. Side effects of clopidogrel were observed in 9 patients (7.1%). This preliminary study shows that 50-mg maintenance dose of clopidogrel may be acceptable in Japanese patients undergoing coronary stenting.
authors.affiliation: Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8677, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Ohkubo
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Kobayashi