title: Transformed lymphoplasmacytic lymphoma involving the main carina: A case report.
abstract: A 41-year-old male was admitted to Nagoya City University Hospital subsequent to experiencing a cough with bloody sputum for a few days. The patient had a 4-year history of lymphoplasmacytic lymphoma (LPL) and had achieved a good partial response to anticancer chemotherapy. Chest computed tomography (CT) showed an endobronchial tumor of the main carina. A bronchoscopy revealed an exophytic tumor at the main carina, and autofluorescence imaging bronchovideoscopy showed that the tumor and surrounding area were magenta in color. The biopsy specimens demonstrated that the endobronchial tumor was composed of large atypical lymphoid cells. The patient was diagnosed with a high-grade transformation of LPL. In addition to describing a rare case of transformed LPL involving the main carina, the present study also summarizes and discusses endobronchial lymphomas, with a brief review of a number of published studies.
authors.affiliation: Department of Medical Oncology and Immunology, Nagoya City University, School of Medical Sciences, Nagoya, Aichi 467-8601, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Nakao
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Oguri
authors.forename: Mikinori
authors.initials: M
authors.lastname: Miyazaki
authors.forename: Hisatoshi
authors.initials: H
authors.lastname: Hijikata
authors.forename: Midori
authors.initials: M
authors.lastname: Yokoyama
authors.forename: Eiji
authors.initials: E
authors.lastname: Kunii
authors.forename: Takehiro
authors.initials: T
authors.lastname: Uemura
authors.forename: Osamu
authors.initials: O
authors.lastname: Takakuwa
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Ohkubo
authors.forename: Ken
authors.initials: K
authors.lastname: Maeno
authors.forename: Akio
authors.initials: A
authors.lastname: Niimi
keywords: autofluorescence bronchoscopy; endobronchial tumor; lymphoplasmacytic lymphoma; transformation