title: Status of primary liver cancer found through routine health check-up.
abstract: This study aimed to investigate the status of primary liver cancers found through a routine health check-up. The data of subjects who were diagnosed with primary liver cancer for the first time through a routine health check-up during a period of 8-yr were analyzed. Primary liver cancers were detected for the first time in 34 subjects among 91,219 routine health check-up subjects. Only 11.8% of primary liver cancer subjects had been under previous surveillance. Of them, 55.8% were positive for HBsAg, 17.7% were positive for anti-HCV, and 8.8% were heavy alcohol comsumers. However, 17.7% of the subjects were neither heavy alcohol consumers nor positive for both HBsAg and anti-HCV. Of the subjects, 50.0% had a single nodular tumor, 23.5% had multi-nodular tumors, and 26.5% had an infiltrative tumor. A routine health check-up may provide beneficial opportunities to detect a liver cancer in a very early stage. It is beneficial to start surveillance in high-risk subjects for liver cancer or to detect any liver cancer in subjects without risk factors of chronic viral hepatitis or heavy alcohol consumption.
authors.affiliation: Department of Internal Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea.
authors.forename: Changhyun
authors.initials: C
authors.lastname: Lee
authors.forename: Jong In
authors.initials: JI
authors.lastname: Yang
authors.forename: Hee Jin
authors.initials: HJ
authors.lastname: Byun
authors.forename: Jung Mook
authors.initials: JM
authors.lastname: Kang
authors.forename: Seoungho
authors.initials: S
authors.lastname: Choi
authors.forename: Jeong Yoon
authors.initials: JY
authors.lastname: Yim
mesh_terms: D000367:Age Factors; D000428:Alcohol Drinking; D055088:Early Detection of Cancer; D006514:Hepatitis B Surface Antigens / Q000097:blood; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000453:epidemiology; D012737:Sex Factors; D012907:Smoking; D011795:Surveys and Questionnaires; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies
keywords: Liver Neoplasms; Mass Screening; Population Surveillance