title: Indications for invasive prenatal diagnostic procedures at a dedicated fetal medicine centre: an 8 year audit 2003-2010.
abstract: OBJECTIVE
  Analyze indications and type of prenatal diagnostic procedures performed.
  
  
  METHODS
  This retrospective audit was conducted at a dedicated fetal medicine center in Petaling Jaya. All invasive prenatal diagnosis procedures performed from 2003 up until 2010 (amniocentesis, chorionic villous sampling and fetal blood sampling) were analyzed.
  
  
  RESULTS
  A total of 1560 invasive prenatal diagnostic procedures were performed during the 8 year period. Advanced maternal age is the leading indication for invasive prenatal diagnostic procedures followed by fetal abnormalities. The fetal loss rate was 0.2% for amniocentesis and 1.2% for CVS.
  
  
  CONCLUSIONS
  Advanced maternal age is the leading indication for invasive prenatal diagnostic procedures at this centre but is on a declining trend. The fetal loss rates are comparable to auditable standards set by professional bodies, in this case, the Royal College of Obstetricians & Gynecologists of London.
authors.affiliation: Sabah Women & Children Hospital (Likas), PO Box 187, 88996, Kota Kinabalu, Sabah, Malaysia. vj1vela@gmail.com.
authors.forename: Vijayan
authors.initials: V
authors.lastname: Valayatham
authors.forename: Raman
authors.initials: R
authors.lastname: Subramaniam
authors.forename: Yap Moy
authors.initials: YM
authors.lastname: Juan
authors.forename: Patrick
authors.initials: P
authors.lastname: Chia
mesh_terms: D000649:Amniocentesis; D015193:Chorionic Villi Sampling; D006801:Humans; D008423:Maternal Age; D011296:Prenatal Diagnosis; D012189:Retrospective Studies