title: Total synthesis and biological evaluation of jerantinine E.
authors.affiliation: Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fédérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015 Lausanne (Switzerland) http://lcso.epfl.ch/
authors.forename: Reto
authors.initials: R
authors.lastname: Frei
authors.forename: Davide
authors.initials: D
authors.lastname: Staedler
authors.forename: Aruna
authors.initials: A
authors.lastname: Raja
authors.forename: Raimo
authors.initials: R
authors.lastname: Franke
authors.forename: Florenz
authors.initials: F
authors.lastname: Sasse
authors.forename: Sandrine
authors.initials: S
authors.lastname: Gerber-Lemaire
authors.forename: Jérôme
authors.initials: J
authors.lastname: Waser
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D030009:Aspidosperma / Q000737:chemistry*; D002460:Cell Line; D002465:Cell Movement / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D026121:Indole Alkaloids; D061986:MCF-7 Cells; D051379:Mice; D008968:Molecular Conformation; D058105:Polymerization / Q000187:drug effects; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014404:Tubulin / Q000378:metabolism; D014748:Vinca Alkaloids / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D026121:Indole Alkaloids; D014404:Tubulin; D014748:Vinca Alkaloids; C000589416:jerantinine E
keywords: alkaloids; cancer; indoles; natural products; total synthesis