title: A new minor homoisoflavonoid from Caesalpinia sappan.
abstract: Homoisoflavonoid is a special type of flavonoid with the perspectives of both chemical diversity and significant biological activities. During our ongoing studies on the discovery of novel homoisoflavonoids from traditional Chinese medicines, a new minor 3,4-di-O-substituted homoisoflavonoid, 3',4-di-O-methylepisappanol (1), was isolated from Caesalpinia sappan, and its structure was determined to be (3R,4R)-3,7-dihydroxy-3-(3'-methoxy-4'-hydroxybenzyl)-4-methoxychroman by various spectroscopic analyses. Meanwhile, a known xanthone derivate, 2-methoxy-3-hydroxyxanthone (2) was also isolated, which is the first example from the genus Caesalpinia.
authors.affiliation: a Institute of Materia Medica, Shandong Academy of Medical Sciences , Jinan , Shandong 250062 , P.R. China.
authors.forename: Huanxin
authors.initials: H
authors.lastname: Zhao
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Kazuo
authors.initials: K
authors.lastname: Koike
authors.forename: Hong
authors.initials: H
authors.lastname: Bai
mesh_terms: D029911:Caesalpinia / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005419:Flavonoids; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D013237:Stereoisomerism; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C000590810:2-methoxy-3-hydroxyxanthone; C000590809:3',4-di-O-methylepisappanol; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D007529:Isoflavones; D044004:Xanthones; C041477:3-hydroxyflavone