title: Treatment outcome after repair of root perforations with mineral trioxide aggregate: a retrospective evaluation of 90 teeth.
abstract: BACKGROUND
  In this retrospective study, the success rate for the repair of root perforations using mineral trioxide aggregate was investigated.
  
  
  METHODS
  One hundred forty consecutive cases of teeth with perforations were included in the sample; 128 finally met the inclusion criteria. All treatments were performed between 1999 and 2009 in a dental office limited to endodontics. Perforations were sealed with mineral trioxide aggregate using a dental operating microscope. Treatment success was assessed by analyzing clinical data and radiographs 1-10 years after treatment. The radiographs were evaluated by 2 independent calibrated examiners. The outcome measure was dichotomized as "healed" or "failure." The relationship between preoperative data and treatment outcome was examined to determine potential prognostic factors.
  
  
  RESULTS
  From 128 teeth, 90 were accessible for recall (70.3%). The mean follow-up interval was 3.4 years. Sixty-six teeth (73.3%) were classified as healed. A significant relationship between treatment success and the presence of a preoperative lesion at the perforation site was found. Those teeth in which a lesion at the perforation site was present before treatment showed a lower healing rate. Teeth with a preoperative communication between the perforation and the oral cavity showed the lowest success rate.
  
  
  CONCLUSIONS
  Two prognostic factors for healing of teeth with perforations were identified. The presence of a preoperative lesion at the perforation site and direct contact between the perforation and the oral cavity were related to lower treatment success rates.
authors.affiliation: Praxis Dr. Bargholz and Partner, Private Practice for Endodontics, Hamburg, Germany. Electronic address: praxis@endodontie.de.
authors.forename: Christian
authors.initials: C
authors.lastname: Krupp
authors.forename: Clemens
authors.initials: C
authors.lastname: Bargholz
authors.forename: Martin
authors.initials: M
authors.lastname: Brüsehaber
authors.forename: Michael
authors.initials: M
authors.lastname: Hülsmann
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017607:Aluminum Compounds / Q000627:therapeutic use*; D017610:Calcium Compounds / Q000627:therapeutic use*; D002126:Calcium Hydroxide / Q000627:therapeutic use; D003786:Dental Pulp Cavity / Q000000981:diagnostic imaging / Q000293:injuries*; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D006171:Gutta-Percha / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008866:Microsurgery / Q000295:instrumentation; D008875:Middle Aged; D010087:Oxides / Q000627:therapeutic use*; D010485:Periapical Periodontitis / Q000150:complications / Q000000981:diagnostic imaging; D016300:Radiography, Bitewing; D012189:Retrospective Studies; D012387:Root Canal Filling Materials / Q000627:therapeutic use*; D012388:Root Canal Irrigants / Q000627:therapeutic use; D012390:Root Canal Therapy / Q000379:methods; D017640:Silicates / Q000627:therapeutic use*; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology; D055815:Young Adult
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants; D017640:Silicates; C086631:mineral trioxide aggregate; D006171:Gutta-Percha; D002126:Calcium Hydroxide
keywords: Mineral trioxide aggregate; root perforation repair; treatment outcome