title: Prevalence of Toxoplasma gondii and Toxocara canis among Patients with Uveitis.
abstract: OBJECTIVE
  To investigate the prevalence of Toxoplasma gondii and Toxocara canis in patients with uveitis.
  
  
  METHODS
  Patients with uveitis were examined. Serum antibodies to T. gondii and T. canis were tested by using the enzyme-linked immunosorbent assay. Polymerase chain reaction (PCR) was done using blood and aqueous humor (AH).
  
  
  RESULTS
  Ninety-eight patients were enrolled. Mean age was 43.5 ± 13.2 years. Six patients were seropositive for T. gondii with the following pattern: anterior uveitis, 1; posterior uveitis with retinitis, 2; pan uveitis, 2. One patient had a positive PCR result for T. gondii in AH, who showed panuveitis. Twenty-three patients were positive to serum IgG for T. canis with the following clinical manifestation: granuloma, 6; pigmented scar, 3; vitritis, 6--but none were PCR positive.
  
  
  CONCLUSIONS
  T. gondii and T. canis are still important causes of uveitis. Ocular toxocariasis is not an uncommon cause of uveitis, even in adults.
authors.affiliation: The Retina Center of Nune Eye Hospital , Seoul , Korea .
authors.forename: Su Jin
authors.initials: SJ
authors.lastname: Lim
authors.forename: Sang Eun
authors.initials: SE
authors.lastname: Lee
authors.forename: Sun Hyun
authors.initials: SH
authors.lastname: Kim
authors.forename: Sung-Hee
authors.initials: SH
authors.lastname: Hong
authors.forename: Yong Sung
authors.initials: YS
authors.lastname: You
authors.forename: Oh Woong
authors.initials: OW
authors.lastname: Kwon
authors.forename: Hyeun Seung
authors.initials: HS
authors.lastname: Kim
mesh_terms: D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D001082:Aqueous Humor / Q000276:immunology; D016054:DNA, Protozoan / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D015995:Prevalence; D011446:Prospective Studies; D056910:Republic of Korea / Q000453:epidemiology; D017166:Toxocara canis / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D014122:Toxoplasma / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis / Q000453:epidemiology* / Q000469:parasitology; D014605:Uveitis / Q000175:diagnosis / Q000453:epidemiology* / Q000469:parasitology
chemical_list: D000913:Antibodies, Protozoan; D016054:DNA, Protozoan
keywords: Ocular toxocariasis; ocular toxoplasmosis; parasite; serologic test; uveitis