title: Morphometrical study of minor salivary gland in xerostomic patients with altered lipid metabolism.
abstract: OBJECTIVE
  To evaluate the correlation between dyslipidemia in patients with oral dryness and the development of non-specific histopathological findings in their labial salivary gland biopsies.
  
  
  METHODS
  Thirty seven patients suffering from oral dryness (18 patients with dyslipidemia and 19 age-matched patients with normal lipid blood levels) underwent labial salivary gland biopsy. Total acinar area (TAA), acinar cell number, acinar lumen area (ALA), duct lumen area (DLA), area occupied by cells in acinus (AoCA), and area of one acinar cell (OAC) were calculated.
  
  
  RESULTS
  A significantly (P < 0.05) increased AoCA, OAC, and DLA in labial glands from patients with impaired lipid metabolism, compared to controls, were found.
  
  
  CONCLUSIONS
  A positive relationship between dyslipidemia and morphological changes in labial salivary glands was obtained.
authors.affiliation: Salivary Gland Clinic and Saliva Diagnostic Laboratory, Department of Oral Medicine, Hadassah Faculty of Dental Medicine, Jerusalem, Israel.
authors.forename: L
authors.initials: L
authors.lastname: Lukach
authors.forename: A
authors.initials: A
authors.lastname: Maly
authors.forename: A
authors.initials: A
authors.lastname: Zini
authors.forename: D J
authors.initials: DJ
authors.lastname: Aframian
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D050171:Dyslipidemias / Q000150:complications / Q000378:metabolism*; D005260:Female; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D012470:Salivary Glands, Minor / Q000473:pathology*; D014987:Xerostomia / Q000150:complications / Q000378:metabolism* / Q000473:pathology*
keywords: Sjogren's syndrome; dyslipidemia; labial salivary glands; oral dryness; xerostomia