title: SdrA, a new DeoR family regulator involved in Streptomyces avermitilis morphological development and antibiotic production.
abstract: The SAV3339 (SdrA) protein of Streptomyces avermitilis, a member of the DeoR family of regulators, was assessed to determine its in vivo function by gene knockdown through the use of cis-encoded noncoding RNA and knockout of the sdrA gene. These analyses revealed that SdrA represents another class of Streptomyces regulator that controls morphological development and antibiotic production.
authors.affiliation: International Center for Biotechnology, Osaka University, Osaka, Japan.
authors.forename: Dana
authors.initials: D
authors.lastname: Ulanova
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kitani
authors.forename: Eiichiro
authors.initials: E
authors.lastname: Fukusaki
authors.forename: Takuya
authors.initials: T
authors.lastname: Nihira
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D015964:Gene Expression Regulation, Bacterial; D055785:Gene Knockdown Techniques; D055786:Gene Knockout Techniques; D013302:Streptomyces / Q000166:cytology* / Q000235:genetics / Q000378:metabolism*; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D014157:Transcription Factors