title: Safety and efficacy of a non-polymeric paclitaxel-eluting microporous stent in real-world percutaneous coronary intervention.
abstract: At present, there is an increasing focus on stents that have a biodegradable polymer coating, rather than a permanent polymer coating. This is due to the fact that following the implantation of a drug-eluting stent (DES) with a permanent polymer coating, the continued existence of the coating may result in a foreign body reaction and delayed re-endothelialization. The aim of the present study was to evaluate the safety and efficacy of a non-polymeric paclitaxel-eluting microporous (YINYI™) stent in real-life percutaneous coronary intervention (PCI) for patients with coronary artery disease (CAD). A total of 686 YINYI™ stents were implanted in 404 patients with CAD in a PCI procedure and outpatient follow-ups were performed 1, 6, 12 and 15 months subsequent to the PCI, respectively. The observation endpoints were major adverse cardiac events (MACEs), including cardiac death, non-fatal myocardial infarction (MI), restenosis, target lesion revascularization, stent thrombosis and recurrence of angina pectoris. The average follow-up time was 15 months. The results revealed that the cumulative incidences of MACEs were as follows: mortality, 0.99%; non-fatal MI, 0.74%; restenosis, 4.0%; and target lesion revascularization, 2.7%. The results at the short- and long-term clinical follow-ups indicated that YINYI™ stents are effective and safe for use in PCI for patients with CAD.
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China.
authors.forename: Shao-Peng
authors.initials: SP
authors.lastname: Wang
authors.forename: Rong-Chong
authors.initials: RC
authors.lastname: Huang
authors.forename: Hao
authors.initials: H
authors.lastname: Zhu
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.forename: Zhen-Guo
authors.initials: ZG
authors.lastname: Zheng
authors.forename: DA
authors.initials: D
authors.lastname: Yin
authors.forename: Jun-Jie
authors.initials: JJ
authors.lastname: Wang
authors.forename: Xu-Chen
authors.initials: XC
authors.lastname: Zhou
keywords: YINYI™ stent; coronary artery disease; follow-up; non-polymeric paclitaxel-eluting microporous stent; percutaneous coronary intervention