title: PillCam small bowel capsule endoscopy gastric passage interval association with patient's complaints and pathological findings: a prospective study.
abstract: OBJECTIVE
  Prolonged gastric transit interval of small bowel video capsule endoscopy (SBCE) can potentially indicate a motility disorder and disrupt whole small bowel visualization. The aim of this study was to prospectively examine the association of prolonged gastric passage interval with symptoms, anthropometric and laboratory factors, and factors related to the SBCE examination, such as indications and pathological findings.
  
  
  METHODS
  This was a prospective single-center study that included 100 patients who underwent SBCE for any indication. Before the examination, clinical, demographic, and anthropometric data were recorded. The patients filled the Gastroparesis Cardinal Symptoms Index (GCSI) questionnaire. We assessed the difference in the study parameters between the prolonged gastric transit (≥45 min) group and the group with a normal gastric transit.
  
  
  RESULTS
  Seventy-six patients had normal gastric passage interval and 24 patients had prolonged gastric passage interval. No significant differences were found between the groups in age, sex, prevalence of diabetes mellitus, use of antimotility drugs, indications for the exam and levels of hemoglobin, C-reactive protein, and albumin. Esophageal and small bowel transition intervals did not vary between both groups. The mean score for any GCSI item and the mean total GCSI score did not differ significantly between the normal and the prolonged gastric passage interval groups. There were no significant differences between the groups in pathological findings in the small bowel.
  
  
  CONCLUSIONS
  In the study population, prolonged SBCE gastric transit interval had no clinical significance, and therefore, probably does not mandate any further gastrointestinal evaluation.
authors.affiliation: aDepartment of Gastroenterology, Chaim Sheba Medical Center, Tel Hashomer bSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Dan
authors.initials: D
authors.lastname: Carter
authors.forename: Rami
authors.initials: R
authors.lastname: Eliakim
authors.forename: Ofir
authors.initials: O
authors.lastname: Har-Noy
authors.forename: Shulamit
authors.initials: S
authors.lastname: Goldstein
authors.forename: Estela
authors.initials: E
authors.lastname: Derazne
authors.forename: Eytan
authors.initials: E
authors.lastname: Bardan
mesh_terms: D000328:Adult; D000368:Aged; D053704:Capsule Endoscopy / Q000009:adverse effects* / Q000295:instrumentation*; D004867:Equipment Design; D005260:Female; D005772:Gastrointestinal Transit; D018589:Gastroparesis / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007421:Intestine, Small / Q000473:pathology*; D007557:Israel; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013997:Time Factors