title: [Optimization of wine-roasting technology of coptidis rhizoma using orthogonal design].
abstract: OBJECTIVE
  To optimize the processing technology of Coptidis Rhizoma roasting with yellow rice wine.
  
  
  METHODS
  The total content of four kinds of alkaloids was used as index. Orthogonal design was applied to study the processing technology of Coptidis Rhizoma roasting with yellow rice wine. L9 (3(4)) orthogonal table was decided with three factors: roasting temperature, roasting time and the amount of yellow rice wine.
  
  
  RESULTS
  Of the three factors, only B factor (roasting time) had obvious effect on the total content of four kinds of alkaloids.
  
  
  CONCLUSIONS
  The optimal processing technology is as follows: Coptidis Rhizoma should be roasted with 15% yellow rice wine for 30 min at 150 degrees C.
authors.affiliation: Property and Pharmacodynamic Key Laboratory of TCM, State Administration of Traditional Chinese Medicine, Department of Pharmaceutics, Hunan University of Tradition Chinese Medicine, Changsha 410202, China. hnsjl@163.com
authors.forename: Ji-Lian
authors.initials: JL
authors.lastname: Shi
authors.forename: Fang
authors.initials: F
authors.lastname: He
authors.forename: Yan-Tao
authors.initials: YT
authors.lastname: Yang
authors.forename: Hong-Bing
authors.initials: HB
authors.lastname: Zhao
authors.forename: Fu-Yuan
authors.initials: FY
authors.lastname: He
mesh_terms: D000470:Alkaloids / Q000032:analysis*; D001599:Berberine / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D039323:Coptis / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D006358:Hot Temperature; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D013678:Technology, Pharmaceutical; D013997:Time Factors; D014920:Wine
chemical_list: D000470:Alkaloids; D004365:Drugs, Chinese Herbal; D001599:Berberine