title: The Brucella pathogens are polarized bacteria.
abstract: Brucella pathogens are responsible for brucellosis, a worldwide zoonosis. They are facultative intracellular pathogens characterized by their asymmetric division and their unipolar growth. This growth modality generates poles with specialized functions (through polar recruitment of polar adhesins or of cell cycle regulators) and progeny cells with potentially different fates.
authors.affiliation: Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 19, 1015 Lausanne, Switzerland.
authors.forename: Charles
authors.initials: C
authors.lastname: Van der Henst
authors.forename: Marie
authors.initials: M
authors.lastname: de Barsy
authors.forename: Angeles
authors.initials: A
authors.lastname: Zorreguieta
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Letesson
authors.forename: Xavier
authors.initials: X
authors.lastname: De Bolle
mesh_terms: D018829:Adhesins, Bacterial; D000818:Animals; D060049:Asymmetric Cell Division; D001426:Bacterial Proteins / Q000378:metabolism; D002002:Brucella / Q000145:classification / Q000502:physiology*; D002006:Brucellosis / Q000382:microbiology; D002453:Cell Cycle; D004260:DNA Repair; D005407:Flagella / Q000502:physiology; D054884:Host-Pathogen Interactions; D006801:Humans
chemical_list: D018829:Adhesins, Bacterial; D001426:Bacterial Proteins
keywords: Adhesion; Brucella; Cell cycle; Growth; Host–pathogen interaction; Polarity