title: Well-being of newly diagnosed women with breast cancer: which factors matter more?
abstract: BACKGROUND
  The assessment of health-related quality of life (HRQL) in newly diagnosed breast cancer patients is necessary to address predictive factors in supportive clinical practice.
  
  
  OBJECTIVE
  The objectives of this study are to evaluate self-reported HRQL within 1 year after breast cancer diagnosis and to determine important factors associated with self-reported impaired HRQL.
  
  
  METHODS
  A cross-sectional study was performed in newly diagnosed breast cancer patients. The statistical analysis included descriptive statistics and stepwise logistic regression modeling.
  
  
  RESULTS
  The survey response rate was 67 % (n = 338). Almost 50 % of the studied population was identified as experiencing anxiety. The impaired HRQL domains were emotional functioning and global health status. Severely expressed symptoms included insomnia, fatigue, and financial difficulties. Poor financial situation, comorbidities, unemployment, and lack of psychological counseling were identified as important predictive factors (p < 0.001).
  
  
  CONCLUSIONS
  Psychosocial, but not clinical, factors were the prevalent predictive factors in impaired HRQL. Early identification of women that are at risk of poorer HRQL and interventions of psychosocial support following breast cancer diagnosis are recommended.
authors.affiliation: Department of Preventive Medicine, Academy of Medicine, Lithuanian University of Health Sciences, Eivenių 4, Kaunas, LT-50161, Lithuania, rugile.ivanauskiene@lsmuni.lt.
authors.forename: Rugilė
authors.initials: R
authors.lastname: Ivanauskienė
authors.forename: Žilvinas
authors.initials: Ž
authors.lastname: Padaiga
authors.forename: Renata
authors.initials: R
authors.lastname: Šimoliūnienė
authors.forename: Giedrė
authors.initials: G
authors.lastname: Smailytė
authors.forename: Auksė
authors.initials: A
authors.lastname: Domeikienė
mesh_terms: D001007:Anxiety / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D001943:Breast Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006304:Health Status; D006801:Humans; D008097:Lithuania / Q000453:epidemiology; D008875:Middle Aged; D010549:Personal Satisfaction; D011788:Quality of Life; D057566:Self Report; D011795:Surveys and Questionnaires