title: Estimation of patient dose in (18)F-FDG and (18)F-FDOPA PET/CT examinations.
abstract: OBJECTIVE
  To estimate specific organ and effective doses to patients resulting from the (18)F-FDG ((18)F-2-deoxy-D-glucose) and (18)F-FDOPA (6-fluoro-((18)F)-L-3, 4-dihydroxyphenylalanine) PET/CT examinations for whole body and brain.
  
  
  METHODS
  Three protocols for whole body and three for brain PET/CT were used. The CTDI values were measured using standard head and body CT phantoms and also computed using a software CT-Expo for dose evaluation from the CT component. OLINDA software based on MIRD method was used for estimating doses from the PET component of the PET/CT examination.
  
  
  RESULTS
  The organ doses from (18)F-FDG and (18)F-FDOPA whole body and brain PET/CT studies were estimated. The total effective dose from a typical protocol of whole body PET/CT examination was 14.4 mSv for females and 11.8 mSv for male patients from (18)F-FDG, whereas it was 11 mSv for female and 9.1 mSv for male patients from (18)F-FDOPA. The total effective doses from a typical protocol for PET/CT studies of brain was 6.5 mSv for females and 5.1 mSv for males from (18)F-FDG whereas it was 3.7 mSv for females and 2.8 mSv for males from (18)F-FDOPA.
  
  
  CONCLUSIONS
  The effective radiation doses from whole body PET/CT examination was approximately 4-8 times higher than the background radiation dose from both (18)F-FDG and (18)F-FDOPA scans, while it was 1-3 times the background radiation dose from PET/CT scans of brain.
authors.affiliation: Department of Radiation Biosciences, Institute of Nuclear Medicine and Allied Sciences, Brig. S.K. Mazumdar Road, Timarpur, Delhi, India.
authors.forename: Aruna
authors.initials: A
authors.lastname: Kaushik
authors.forename: Abhinav
authors.initials: A
authors.lastname: Jaimini
authors.forename: Madhavi
authors.initials: M
authors.lastname: Tripathi
authors.forename: Maria
authors.initials: M
authors.lastname: D'Souza
authors.forename: Rajnish
authors.initials: R
authors.lastname: Sharma
authors.forename: Anil K
authors.initials: AK
authors.lastname: Mishra
authors.forename: Anupam
authors.initials: A
authors.lastname: Mondal
authors.forename: Bilikere S
authors.initials: BS
authors.lastname: Dwarakanath
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D009928:Organ Specificity; D049268:Positron-Emission Tomography / Q000379:methods; D011829:Radiation Dosage; D011874:Radiometry; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed / Q000379:methods; D055815:Young Adult
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; C043437:fluorodopa F 18; D004295:Dihydroxyphenylalanine