title: Dynamins are forever: MxB inhibits HIV-1.
abstract: Human MxA (MX1) protein is an interferon-induced restriction factor for a diverse range of viruses, whereas the related MxB (MX2) protein was thought to lack such activity. Three recent papers, including one in this issue of Cell Host & Microbe, show that MxB inhibits human immunodeficiency virus type 1 (HIV-1) infection.
authors.affiliation: Institute of Virology, Department of Medical Microbiology and Hygiene, University of Freiburg, D-79104 Freiburg, Germany. Electronic address: otto.haller@uniklinik-freiburg.de.
authors.forename: Otto
authors.initials: O
authors.lastname: Haller
mesh_terms: D021984:Cyclophilin A / Q000378:metabolism*; D015658:HIV Infections / Q000517:prevention & control* / Q000821:virology*; D015497:HIV-1 / Q000276:immunology* / Q000502:physiology*; D054884:Host-Pathogen Interactions; D006801:Humans; D016898:Interferon-alpha / Q000276:immunology*; D007372:Interferons / Q000276:immunology*; D064547:Myxovirus Resistance Proteins / Q000378:metabolism*; D016662:Virus Integration / Q000276:immunology*
chemical_list: D016898:Interferon-alpha; C579068:MX2 protein, human; D064547:Myxovirus Resistance Proteins; D007372:Interferons; D021984:Cyclophilin A