title: Glomus tumor of the shoulder: A case report and review of the literature.
abstract: Glomus tumors are benign neoplasms that arise from neuromyoarterial glomus bodies, with clinical manifestations that include acute pain, cold intolerance and tenderness. Glomus tumors may occur anywhere in the skin, soft tissue or gastrointestinal tract, but are most frequently encountered in the nail bed of the hands. The present study reports the case of a 30-year-old female with a history of shoulder pain caused by a cystic neoformation. Following surgery, a microscopic examination revealed nests of small cells of a rounded and regular shape. The tumor cells exhibited positive expression for CD34 and smooth muscle actin. This study supports and confirms the fact that a glomus tumor is a benign neoplasm that may occur in multiple locations. Therefore, the significance of a histological and immunohistochemical approach for a correct characterization of this lesion is required.
authors.affiliation: Division of Pathological Anatomy, Department of Surgery, Medical, Molecular and Critical Area Pathology, University of Pisa, Pisa, Italy.
authors.forename: Agnese
authors.initials: A
authors.lastname: Proietti
authors.forename: Greta
authors.initials: G
authors.lastname: Alì
authors.forename: Francesca
authors.initials: F
authors.lastname: Quilici
authors.forename: Pietro
authors.initials: P
authors.lastname: Bertoglio
authors.forename: Alfredo
authors.initials: A
authors.lastname: Mussi
authors.forename: Gabriella
authors.initials: G
authors.lastname: Fontanini
keywords: extradigital glomus tumour; glomangioma; glomus tumour; review; shoulder