title: Vitamin D and physical performance in older men and women visiting the emergency department because of a fall: data from the improving medication prescribing to reduce risk of falls (IMPROveFALL) study.
abstract: OBJECTIVE
  To investigate whether serum 25-hydroxy vitamin D (25(OH)D) is associated with physical performance in men and women.
  
  
  METHODS
  Cross-sectional.
  
  
  METHODS
  Emergency departments (EDs) of five hospitals.
  
  
  METHODS
  Older adults who visited an ED because of a fall (N = 616).
  
  
  METHODS
  Physical performance was assessed using the Timed Up and Go Test, the Five Time Sit to Stand Test, handgrip strength, and the tandem stand test. Multivariate linear regression was used to assess the association between physical performance and log-transformed 25(OH)D concentration adjusted for potential confounders.
  
  
  RESULTS
  In men, higher serum 25(OH)D concentration was significantly associated with better handgrip strength (regression coefficient (B) = 3.86, 95% confidence interval (CI) = 2.04-5.69), faster TUG time (B = -2.82, 95% CI = -4.91 to -0.73), and faster FTSS time (B = -3.39, 95% CI = -5.67 to -1.11). In women, higher serum 25(OH)D concentration was significantly associated with faster TUG time (B = -2.68, 95% CI = -4.87 to -0.49).
  
  
  CONCLUSIONS
  A positive association was found between serum 25(OH)D level and physical performance in men and women. Intervention studies are needed of vitamin D-deficient older men and women to further investigate the effect of vitamin D supplementation in this group.
authors.affiliation: Section of Geriatric Medicine, Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands; Department of Surgery-Traumatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
authors.forename: Nicole D A
authors.initials: ND
authors.lastname: Boyé
authors.forename: Christian
authors.initials: C
authors.lastname: Oudshoorn
authors.forename: Nathalie
authors.initials: N
authors.lastname: van der Velde
authors.forename: Esther M M
authors.initials: EM
authors.lastname: van Lieshout
authors.forename: Oscar J
authors.initials: OJ
authors.lastname: de Vries
authors.forename: Paul
authors.initials: P
authors.lastname: Lips
authors.forename: Ed F
authors.initials: EF
authors.lastname: van Beeck
authors.forename: Peter
authors.initials: P
authors.lastname: Patka
authors.forename: Tischa J M
authors.initials: TJ
authors.lastname: van der Cammen
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control; D000368:Aged; D003430:Cross-Sectional Studies; D004636:Emergency Service, Hospital; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D053580:Muscle Strength; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D
keywords: falls; muscle strength; older adults; physical performance; vitamin D