title: Rapidly progressing primary splenic angiosarcoma with fatal hemorrhagic event.
abstract: Primary angiosarcoma of the spleen is an extremely rare malignancy. Splenic angiosarcoma is difficult to diagnose, and treatment is often challenging. The prognosis is dismal, with a mean survival of less than 1 year. Currently, no standard treatment methods have been established. Anecdotal reports suggest that early diagnosis and prompt splenectomy followed by cytotoxic chemotherapy can be effective treatment modalities. We report a case of rapidly progressing primary splenic angiosarcoma with multiple liver and bone metastases and a fatal hemorrhagic outcome.
authors.forename: Eun Ae
authors.initials: EA
authors.lastname: Cho
authors.forename: Won-Young
authors.initials: WY
authors.lastname: Choi
authors.forename: Seung-Hun
authors.initials: SH
authors.lastname: Kim
authors.forename: Ji-Yun
authors.initials: JY
authors.lastname: Hong
authors.forename: Sung-Hoon
authors.initials: SH
authors.lastname: Jung
authors.forename: Min-Jee
authors.initials: MJ
authors.lastname: Kim
authors.forename: Jun-Eul
authors.initials: JE
authors.lastname: Hwang
authors.forename: Woo-Kyun
authors.initials: WK
authors.lastname: Bae
authors.forename: Hyun-Jeong
authors.initials: HJ
authors.lastname: Shim
authors.forename: Kyung-Hwa
authors.initials: KH
authors.lastname: Lee
authors.forename: Sang-Hee
authors.initials: SH
authors.lastname: Cho
authors.forename: Ik-Joo
authors.initials: IJ
authors.lastname: Chung
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary; D018450:Disease Progression; D017809:Fatal Outcome; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000188:drug therapy*; D006470:Hemorrhage; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D011379:Prognosis; D013160:Splenic Neoplasms / Q000175:diagnosis / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed
keywords: Angiosarcoma,; Chemotherapy; Spleen,; Splenectomy,