title: Effect of Terminalia chebula extract and chlorhexidine on salivary pH and periodontal health: 2 weeks randomized control trial.
abstract: A double blind, randomized, controlled study with three parallel treatment groups was done to evaluate the efficacy of a Terminalia chebula 10% mouth rinse compared with chlorhexidine 0.12% mouth rinse, applied two times daily for 2 weeks, in the treatment of dental plaque and gingivitis. Seventy-eight patients were included in the study. The efficacy variables were periodontal indices on days 0, 7 and 14 after commencement of therapy. Twenty six patients received chlorhexidine mouth rinse, twenty six Terminalia chebula mouth rinse and twenty six received saline solution. The clinical parameters were significantly reduced by both chlorhexidine and Terminalia chebula mouth rinse although no significant difference was seen between the two groups (P > 0.05). This study demonstrated that Terminalia chebula mouth rinse is effective in reducing microbial plaque, gingival inflammation and neutralizing salivary pH.
authors.affiliation: Department of Public Health Dentistry, Teerthanker Mahaveer Dental College and Research Centre, Moradabad, Uttar Pradesh, India.
authors.forename: Devanand
authors.initials: D
authors.lastname: Gupta
authors.forename: D J
authors.initials: DJ
authors.lastname: Bhaskar
authors.forename: Rajendra Kumar
authors.initials: RK
authors.lastname: Gupta
authors.forename: Bushra
authors.initials: B
authors.lastname: Karim
authors.forename: Vipul
authors.initials: V
authors.lastname: Gupta
authors.forename: Himanshu
authors.initials: H
authors.lastname: Punia
authors.forename: Manu
authors.initials: M
authors.lastname: Batra
authors.forename: Ankita
authors.initials: A
authors.lastname: Jain
authors.forename: Amit
authors.initials: A
authors.lastname: Agarwal
authors.forename: Pradeep
authors.initials: P
authors.lastname: Singh
mesh_terms: D000328:Adult; D002710:Chlorhexidine / Q000627:therapeutic use*; D003773:Dental Plaque / Q000188:drug therapy*; D003774:Dental Plaque Index; D004311:Double-Blind Method; D005260:Female; D005638:Fruit / Q000737:chemistry; D005891:Gingivitis / Q000188:drug therapy*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D009067:Mouthwashes / Q000627:therapeutic use*; D010512:Periodontal Index; D010936:Plant Extracts / Q000627:therapeutic use*; D012463:Saliva / Q000737:chemistry; D029766:Terminalia / Q000737:chemistry*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D009067:Mouthwashes; D010936:Plant Extracts; D002710:Chlorhexidine
keywords: Terminalia chebula; chlorhexidine; gingival index; mouthwash; plaque index