title: Hypophosphatemic vitamin D-resistant osteomalacia: A case report.
abstract: This study concerns the case of a 59-year-old woman who was admitted to hospital after experiencing systemic bone pain and muscle weakness for more than 2 years. The patient was diagnosed with numerous fractures via bone imaging emission computed tomography (ECT) and hypophosphatemia. Laboratory results showed a high alkaline phosphatase concentration. Thyroid nodules were visible on the thyroid and parathyroid glands during ultrasound examinations. However, no symptomatic or biochemical improvement was observed following a thyroid nodulectomy. The patient was administered large doses of neutral phosphate preparations, vitamin D3 and calcium. A gradual improvement in the condition of the patient was observed. For bone pain associated with multiple fractures in elderly patients, calcium and phosphorus metabolism disorders, and active vitamin D deficiency should be considered and an early diagnosis should be performed.
authors.affiliation: Department of Neurology, Jinan Military General Hospital, Jinan, Shandong 250031, P.R. China.
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.forename: Xia
authors.initials: X
authors.lastname: Cao
authors.forename: Bingzhen
authors.initials: B
authors.lastname: Cao
keywords: adult-onset hypophosphatemic vitamin D-resistant osteomalacia; parathyroid; thyroid; tumor-induced osteomalacia