title: Ultrastructural characteristics of molecular release of secretory products from thyroid mast cells induced by lipopolysaccharide.
abstract: Ultrastructural characteristics of molecular release of secretory products from thyroid mast cells during different periods after LPS injection were studied in rats. The main morphological manifestation of this mechanism was progressing hydration of the hyaloplasm around secretory granules and dissolution and release of osmiophilic contents from the granules to the cytoplasm with the formation of a hydropic vacuole at the site of the granule.
authors.affiliation: Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow, Russia. yaglova@mail.ru.
authors.forename: N V
authors.initials: NV
authors.lastname: Yaglova
authors.forename: V V
authors.initials: VV
authors.lastname: Yaglov
mesh_terms: D000818:Animals; D015550:Cell Degranulation / Q000502:physiology; D003594:Cytoplasmic Granules / Q000378:metabolism / Q000648:ultrastructure*; D008070:Lipopolysaccharides; D008297:Male; D008407:Mast Cells / Q000187:drug effects / Q000378:metabolism*; D008854:Microscopy, Electron; D051381:Rats; D017208:Rats, Wistar; D022142:Secretory Vesicles / Q000378:metabolism / Q000648:ultrastructure*; D013961:Thyroid Gland / Q000166:cytology / Q000378:metabolism*
chemical_list: D008070:Lipopolysaccharides