title: [Wide-field fundus autofluorescence in non-infectious posterior uveitis].
abstract: BACKGROUND
  Posterior uveitis comprises a heterogeneous group of diseases with inflammatory alterations of the posterior fundus and is a common cause of visual impairment and blindness. The goal of this study was to evaluate the diagnostic value of wide-field fundus autofluorescence (FAF) in patients with non-infectious posterior uveitis and chorioretinal alterations.
  
  
  METHODS
  In this study 73 eyes from 51 patients were included. Best-corrected visual acuity, wide-field color and FAF images achieved by a wide-field scanning laser opththalmoscope (SLO, Optomap P200Tx, Optos PLC, Dunfermline UK) and a full ophthalmological examination were obtained from each patient. A systematic analysis of chorioretinal alterations detected with FAF and color images was conducted followed by the evaluation of the diagnostic information of wide-field FAF compared to the clinical finding and wide-field color images.
  
  
  RESULTS
  Of the 73 eyes included in the study 52 showed peripheral alterations. In 32 cases wide-field FAF images revealed a greater number and more extensive chorioretinal alterations than the corresponding wide-field color images of the posterior fundus.
  
  
  CONCLUSIONS
  In this study wide-field FAF images showed more chorioretinal alterations than seen in funduscopy or in color SLO images. Therefore, wide-field FAF images offer important additional information for detection and documentation of peripheral and central chorioretinal alterations.
authors.forename: L
authors.initials: L
authors.lastname: Reznicek
authors.forename: F
authors.initials: F
authors.lastname: Seidensticker
authors.forename: C
authors.initials: C
authors.lastname: Stumpf
authors.forename: J
authors.initials: J
authors.lastname: Langer
authors.forename: S
authors.initials: S
authors.lastname: Thurau
authors.forename: M W
authors.initials: MW
authors.lastname: Ulbig
authors.forename: A
authors.initials: A
authors.lastname: Kampik
authors.forename: A
authors.initials: A
authors.lastname: Neubauer
authors.forename: M
authors.initials: M
authors.lastname: Kernt
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001424:Bacterial Infections / Q000473:pathology; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008297:Male; D018613:Microscopy, Confocal / Q000379:methods*; D008856:Microscopy, Fluorescence / Q000379:methods*; D008875:Middle Aged; D015203:Reproducibility of Results; D012160:Retina / Q000473:pathology*; D042262:Retinoscopy / Q000379:methods*; D012680:Sensitivity and Specificity; D014602:Uvea / Q000473:pathology*; D015866:Uveitis, Posterior / Q000473:pathology*; D055815:Young Adult