title: A Unique Case of Classic Kaposi's sarcoma restricted to the toes.
abstract: BACKGROUND
  Kaposi's sarcoma associated-herpesvirus causes all forms of Kaposi's sarcoma, and six major subtypes have been described based on the amino acid sequences of the open reading frame K1.
  
  
  METHODS
  A 71-year-old man from China, HIV negative, presented with nodules on the dorsal aspect of his toes. Biopsy confirmed the diagnosis of Kaposi's sarcoma and virology studies of his blood and saliva confirmed the presence of Kaposi's sarcoma associated-herpesvirus infection. Viral genotyping was consistent with subtype C3. Intervention has been deferred as our patient has remained clinically asymptomatic and without evident growth of his lesions over a 2-year follow up.
  
  
  CONCLUSIONS
  We herein report the first known case of Kaposi's sarcoma restricted to the toes caused by the viral subtype C3 in an HIV-negative patient from Harbin, China.
authors.affiliation: Mount Sinai Medical Center, New York, NY 10029, USA;
authors.forename: Anne S
authors.initials: AS
authors.lastname: Renteria
authors.forename: Vickie A
authors.initials: VA
authors.lastname: Marshall
authors.forename: Yanyu
authors.initials: Y
authors.lastname: Sun
authors.forename: Porselvi
authors.initials: P
authors.lastname: Chockalingam
authors.forename: Jay S
authors.initials: JS
authors.lastname: Cooper
authors.forename: Yiwu
authors.initials: Y
authors.lastname: Huang
authors.forename: Denise
authors.initials: D
authors.lastname: Whitby
keywords: China; HIV; KSHV; Kaposi's sarcoma; human herpesvirus-8 subtypes; viral phylogeny