title: Association between central obesity and circadian parameters of blood pressure from the korean ambulatory blood pressure monitoring registry: Kor-ABP registry.
abstract: Central obesity has been reported as a risk for atherosclerosis and metabolic syndrome. The influence of central obesity on diurnal blood pressure (BP) has not been established. In this study, we investigated the influence of central obesity on the circadian parameters of BP by 24 hr ambulatory BP monitoring. Total 1,290 subjects were enrolled from the Korean Ambulatory BP registry. Central obesity was defined as having a waist circumference≥90 cm in males and ≥85 cm in females. The central-obese group had higher daytime systolic BP (SBP), nighttime SBP and diastolic BP (DBP) than the non-obese group (all, P<0.001). There were no differences in nocturnal dipping (ND) patterns between the groups. Female participants showed a higher BP mean difference (MD) than male participants with concerns of central obesity (daytime SBP MD 5.28 vs 4.27, nighttime SBP MD 6.48 vs 2.72) and wider pulse pressure (PP). Central obesity within the elderly (≥65 yr) also showed a higher BP MD than within the younger group (daytime SBP MD 8.23 vs 3.87, daytime DBP 4.10 vs 1.59). In conclusion, central obesity has no influence on nocturnal dipping patterns. However, higher SBP and wider PP are associated with central obesity, which is accentuated in women.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, School of Medicine, Ewha Womans University, Seoul, Korea.
authors.forename: In Sook
authors.initials: IS
authors.lastname: Kang
authors.forename: Wook Bum
authors.initials: WB
authors.lastname: Pyun
authors.forename: Jinho
authors.initials: J
authors.lastname: Shin
authors.forename: Ju Han
authors.initials: JH
authors.lastname: Kim
authors.forename: Soon Gil
authors.initials: SG
authors.lastname: Kim
authors.forename: Gil Ja
authors.initials: GJ
authors.lastname: Shin
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D044466:Asian People; D001794:Blood Pressure / Q000502:physiology; D018660:Blood Pressure Monitoring, Ambulatory; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D056128:Obesity, Abdominal / Q000150:complications* / Q000453:epidemiology* / Q000473:pathology; D012042:Registries; D056910:Republic of Korea / Q000453:epidemiology; D012737:Sex Factors; D055105:Waist Circumference
keywords: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Obesity, Abdominal