title: Sampling scheme and compressed sensing applied to solid-state NMR spectroscopy.
abstract: We describe the incorporation of non-uniform sampling (NUS) compressed sensing (CS) into oriented sample (OS) solid-state NMR for stationary aligned samples and magic angle spinning (MAS) Solid-state NMR for unoriented 'powder' samples. Both simulated and experimental results indicate that 25-33% of a full linearly sampled data set is required to reconstruct two- and three-dimensional solid-state NMR spectra with high fidelity. A modest increase in signal-to-noise ratio accompanies the reconstruction.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0307, United States.
authors.forename: Eugene C
authors.initials: EC
authors.lastname: Lin
authors.affiliation: Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0307, United States. Electronic address: sopella@ucsd.edu.
authors.forename: Stanley J
authors.initials: SJ
authors.lastname: Opella
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D003627:Data Interpretation, Statistical; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D016012:Poisson Distribution; D011208:Powders; D015203:Reproducibility of Results; D059629:Signal-To-Noise Ratio
chemical_list: D011208:Powders
keywords: Compressed sensing; Membrane proteins; Non-uniform sampling; Oriented samples; Protein NMR; Sensitivity; Solid-state NMR