title: Response initiation in young adults at risk for psychosis in the Northern Finland 1986 Birth Cohort.
abstract: BACKGROUND
  This is one of the very few studies to investigate the specific executive function/processing speed component of response initiation in subjects at familial risk (FR) for psychosis, and the first such study in subjects at clinical risk (CR) for psychosis.
  
  
  METHODS
  Participants (N = 177) were members of the general population-based Northern Finland 1986 Birth Cohort in the following four groups: FR for psychosis (n = 62), CR for psychosis (n = 21), psychosis (n = 25) and control subjects (n = 69). The response initiation of these groups was compared in three different tests: Semantic fluency, Stockings of Cambridge and Spatial working memory.
  
  
  RESULTS
  The two risk groups did not differ significantly from control group, but differed from, and outperformed the psychosis group in semantic fluency response initiation.
  
  
  CONCLUSIONS
  Response initiation deficits were not evident in a non-help seeking psychosis high-risk sample.
authors.affiliation: a Department of Psychiatry , Institute of Clinical Medicine, University of Oulu , Oulu , Finland.
authors.forename: S
authors.initials: S
authors.lastname: Mukkala
authors.forename: T
authors.initials: T
authors.lastname: Ilonen
authors.forename: J
authors.initials: J
authors.lastname: Koskela
authors.forename: T
authors.initials: T
authors.lastname: Nordström
authors.forename: J
authors.initials: J
authors.lastname: Loukkola
authors.forename: J
authors.initials: J
authors.lastname: Miettunen
authors.forename: J H
authors.initials: JH
authors.lastname: Barnett
authors.forename: G K
authors.initials: GK
authors.lastname: Murray
authors.forename: P B
authors.initials: PB
authors.lastname: Jones
authors.forename: M
authors.initials: M
authors.lastname: Heinimaa
authors.forename: E
authors.initials: E
authors.lastname: Jääskeläinen
authors.forename: P
authors.initials: P
authors.lastname: Mäki
authors.forename: I
authors.initials: I
authors.lastname: Moilanen
authors.forename: J
authors.initials: J
authors.lastname: Veijola
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D056344:Executive Function / Q000502:physiology*; D005192:Family Health; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D007231:Infant, Newborn; D008137:Longitudinal Studies; D008297:Male; D008570:Memory, Short-Term / Q000502:physiology*; D011618:Psychotic Disorders / Q000453:epidemiology* / Q000503:physiopathology*; D012307:Risk Factors; D012660:Semantics; D055815:Young Adult