title: [Influence of superfine grinding on micromeritic properties of Scutellaria baicalensis].
abstract: OBJECTIVE
  To study the micromeritic properties of different particle size of Scutellaria baicalensis and provide a basis for being directly used or as raw material of Chinese herba preparation.
  
  
  METHODS
  Size distribution, surface area and pore volume, contact angle, angle of repose and bulk density, moisture absorption, micromorphology, Infrared spectrum, HPLC fingerprint were used to evaluate the differences of micromeritic properties of 4 kinds of Scutellaria baicalensis superfine grinding.
  
  
  RESULTS
  With the particle size of powders decreased, size distribution and bulk density decreased, the surface area and pore volume, contact angle and moisture absorption increased, angle of repose first increased and then decreased. Infrared spectrum and HPLC fingerprint showed no change of chemical composition of Scutellaria baicalensis.
  
  
  CONCLUSIONS
  Different particle size of Scutellaria baicalensis leads to the differences of micromeritic properties. Superfine grinding III is determined as a better particle size.
authors.affiliation: Chengdu University of Traditional Chinese Medicine/Provincial and State Constructed Key Laboratory Breeding Base of System Research and Development of Chinese Herbal Medicine Resource, Chengdu 611137, China. 821004405@qq.com
authors.forename: Nian-Ming
authors.initials: NM
authors.lastname: Wang
authors.forename: Ding-Kun
authors.initials: DK
authors.lastname: Zhang
authors.forename: Ming
authors.initials: M
authors.lastname: Yang
authors.forename: Chun-Feng
authors.initials: CF
authors.lastname: Qin
authors.forename: Li
authors.initials: L
authors.lastname: Han
authors.forename: Zhe-Tong
authors.initials: ZT
authors.lastname: Su
authors.forename: Zhi-Ping
authors.initials: ZP
authors.lastname: Guo
mesh_terms: D002626:Chemistry, Pharmaceutical; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D010316:Particle Size; D018517:Plant Roots / Q000737:chemistry; D011208:Powders; D015203:Reproducibility of Results; D031364:Scutellaria baicalensis / Q000737:chemistry*; D012995:Solubility; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D004365:Drugs, Chinese Herbal; D011208:Powders