title: Fever of unknown origin successfully treated by oren-gedoku-to (huanglian-jie-du-tang).
abstract: Oren-gedoku-to is a traditional medicine used for treating inflammatory conditions and is given by prescription in Japan, People's Republic of China, and Korea. Its anti-inflammatory effect is related to the arachidonate cascade and inhibition of cyclo-oxygenase, but research on other anti-inflammatory pathways is ongoing. We report a case of fever of unknown origin in a 33-year-old woman. The possibility of infection due to human immunodeficiency virus, autoimmune, neoplastic, or other disease was examined and excluded. Oren-gedoku-to was successfully used to treat her symptoms and may thus be a suitable treatment for patients with undiagnosed fever of unknown origin.
authors.affiliation: Division of Traditional Japanese Medicine, Department of General Medicine and Emergency Care, Faculty of Medicine, Toho University, Tokyo, Japan.
authors.forename: Koichiro
authors.initials: K
authors.lastname: Tanaka
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nara
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Nishimura
authors.forename: Keiko
authors.initials: K
authors.lastname: Serizawa
authors.forename: Taito
authors.initials: T
authors.lastname: Miyazaki
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Urita
authors.forename: Oto
authors.initials: O
authors.lastname: Miura
keywords: fever of unknown origin; huanglian-jie-du-tang; kampo; oren-gedoku-to