title: Bioactive metabolites isolated from Penicillium sp. YY-20, the endophytic fungus from Ginkgo biloba.
abstract: Six known metabolites, adenosine (1), methyl β-D-ribofuranoside (2), adenine (3), 2'-deoxyadenosine (4), 3-methylpiperazine-2,5-dione (5) and 2'-deoxyuridine (6), were isolated from the extracts of the endophytic fungus Penicillium sp. YY-20 isolated from the root of Ginkgo biloba, and their structures were elucidated by spectroscopic methods. The antioxidant and growth-promoting activities of these compounds were first evaluated. The results indicated that compounds 1, 3 and 4 exhibited potential DPPH-scavenging activities compared with positive control. In addition, all the compounds (except 5) stimulated seed germination of Raphanus sativus, Brassica napus and Brassica chinensis but had weak stimulating effect on their root and hypocotyl growth.
authors.affiliation: a College of Science, Northwest A&F University , Yangling , Shaanxi 712100 , P.R. China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Yuan
authors.forename: Jun-Mian
authors.initials: JM
authors.lastname: Tian
authors.forename: Jian
authors.initials: J
authors.lastname: Xiao
authors.forename: Qi
authors.initials: Q
authors.lastname: Shao
authors.forename: Jin-Ming
authors.initials: JM
authors.lastname: Gao
mesh_terms: D000225:Adenine / Q000737:chemistry / Q000302:isolation & purification; D000241:Adenosine / Q000737:chemistry / Q000302:isolation & purification; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000494:pharmacology; D001937:Brassica / Q000187:drug effects / Q000254:growth & development; D003839:Deoxyadenosines / Q000737:chemistry / Q000302:isolation & purification; D003857:Deoxyuridine / Q000737:chemistry / Q000302:isolation & purification; D020441:Ginkgo biloba / Q000382:microbiology*; D006133:Growth Substances / Q000302:isolation & purification; D015394:Molecular Structure; D010407:Penicillium / Q000737:chemistry*; D010851:Picrates / Q000494:pharmacology; D018517:Plant Roots / Q000382:microbiology; D031224:Raphanus / Q000187:drug effects / Q000254:growth & development
chemical_list: D000975:Antioxidants; D001688:Biological Products; D001713:Biphenyl Compounds; D003839:Deoxyadenosines; D006133:Growth Substances; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl; D000225:Adenine; D000241:Adenosine; C058118:2'-deoxyadenosine; D003857:Deoxyuridine