title: Use of the translabyrinthine approach to repair congenital spontaneous cerebrospinal fluid leakage in five Chinese patients with Mondini dysplasia.
abstract: OBJECTIVE
  To introduce a more effective surgical technique for the repair of spontaneous incurable cerebrospinal fluid (CSF) leakage (CSF otorrhea).
  
  
  METHODS
  The cases of five Chinese patients with Mondini dysplasia and CSF leakage were reviewed. All patients presented with rhinorrhea or otorrhea from childhood and recurrent meningitis attacks. CSF leakage was repaired surgically using the translabyrinthine approach.
  
  
  RESULTS
  Facial paralysis occurred in the first two patients, but was cured 2 months later. The other three patients recovered well and had no facial paralysis or complication. CSF leakage did not recur in any patient after follow-up periods of 0.5-3 years.
  
  
  CONCLUSIONS
  Mondini dysplasia with CSF leakage is rare. Adequate diagnosis and treatment are required to avoid life-threatening complications, such as meningitis. We recommend the translabyrinthine approach as an alternative surgical technique that reduces recurrence.
authors.affiliation: Department of Neurosurgery Division 9 and Otolaryngeal-Head Neck Surgery, Beijing Tiantan Hospital, Capital University of Medical Science, Beijing, China; Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China.
authors.forename: H J
authors.initials: HJ
authors.lastname: Yi
authors.forename: H
authors.initials: H
authors.lastname: Guo
authors.forename: W
authors.initials: W
authors.lastname: Ch
authors.forename: S M
authors.initials: SM
authors.lastname: Yang
authors.forename: P N
authors.initials: PN
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D002558:Cerebrospinal Fluid Otorrhea / Q000151:congenital* / Q000000981:diagnostic imaging* / Q000601:surgery*; D002559:Cerebrospinal Fluid Rhinorrhea / Q000151:congenital* / Q000175:diagnosis / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D002681:China; D003051:Cochlea / Q000002:abnormalities* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008581:Meningitis / Q000517:prevention & control; D013506:Otologic Surgical Procedures / Q000379:methods*; D011183:Postoperative Complications / Q000503:physiopathology; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome; D055815:Young Adult
keywords: Cerebrospinal fluid leakage; Mondini dysplasia; Translabyrinthine