title: Polymorphisms in the MTRN1A gene and their effects on the productive and reproductive traits in buffaloes.
abstract: The main environmental factor that affects the regulation of reproductive seasonality is photoperiod through its effects on melatonin secretion. The melatonin receptor MTRN1A appears to be involved in regulating the reproductive seasonality and milk production in the period. The aim of this study was to identify polymorphisms in the MTRN1A gene and their possible associations with milk, fat and protein productions, fat and protein percentages, age at first calving, and first calving interval in buffaloes. Three genotypes (CC, CT, and TT) were identified by PCR-RFLP, and there was a significant association with protein percentage (P < 0.0001). Further studies are necessary to better understand the influence of melatonin gene and their receptors in the productive functions of buffaloes.
authors.affiliation: Animal Science Department, São Paulo State University, Via de acesso Professor Paulo Donato Castelane, 14884-900, Jaboticabal, São Paulo, Brazil.
authors.forename: Larissa
authors.initials: L
authors.lastname: Zetouni
authors.forename: Gregório Miguel Ferreira
authors.initials: GM
authors.lastname: de Camargo
authors.forename: Patricia Dias
authors.initials: PD
authors.lastname: da Silva Fonseca
authors.forename: Diercles Francisco
authors.initials: DF
authors.lastname: Cardoso
authors.forename: Fernanda Maria Monsalves
authors.initials: FM
authors.lastname: Gil
authors.forename: Naudin Alejandro
authors.initials: NA
authors.lastname: Hurtado-Lugo
authors.forename: Rusbel Raul
authors.initials: RR
authors.lastname: Aspilcueta-Borquis
authors.forename: Marcelo
authors.initials: M
authors.lastname: Cervini
authors.forename: Humberto
authors.initials: H
authors.lastname: Tonhati
mesh_terms: D000818:Animals; D002020:Buffaloes / Q000235:genetics / Q000502:physiology*; D005260:Female; D005786:Gene Expression Regulation / Q000502:physiology; D005838:Genotype; D007774:Lactation / Q000235:genetics / Q000502:physiology; D017440:Photoperiod; D011110:Polymorphism, Genetic; D011247:Pregnancy; D044122:Receptor, Melatonin, MT1 / Q000235:genetics / Q000378:metabolism*; D012098:Reproduction / Q000235:genetics* / Q000502:physiology
chemical_list: D044122:Receptor, Melatonin, MT1