title: The relation of platelet-lymphocyte ratio and coronary collateral circulation in patients with stable angina pectoris and chronic total occlusion.
abstract: OBJECTIVE
  We aimed to investigate the relationship between the platelet-lymphocyte ratio (PLR) and coronary collateral circulation (CCC) in patients with stable angina pectoris (SAP) and chronic total occlusion (CTO).
  
  
  METHODS
  A total of 294 patients with both SAP and CTO were classified according to their Rentrop collateral grades as either poor (Rentrop grades/0-1) or good (Rentrop grades/2-3).
  
  
  RESULTS
  The PLR values were significantly higher in patients with poor CCC than in those with good CCC (156.8 + 30.7 vs 132.1 + 24.4, P < 0.001). In regression analysis, PLR (unit = 10) [odds ratio 1.48, 95% confidence interval (CI) 1.33 -1.65; P < 0.001] and high-sensitivity C-reactive protein were found to be the independent predictors of poor CCC. In receiver operator characteristic curve analysis, optimal cut-off value of PLR to predict poor CCC was found as 138.1, with 76% sensitivity and 65% specificity.
  
  
  CONCLUSIONS
  PLR may be an important, simple, and cost effective tool predicting the degree of collateralization in patients with SAP and CTO.
authors.affiliation: Department of Cardiology, Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey gokselacar81@hotmail.com.
authors.forename: Göksel
authors.initials: G
authors.lastname: Açar
authors.affiliation: Department of Cardiology, Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey.
authors.forename: Mehmet Emin
authors.initials: ME
authors.lastname: Kalkan
authors.affiliation: Department of Cardiology, Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey.
authors.forename: Anıl
authors.initials: A
authors.lastname: Avci
authors.affiliation: Department of Cardiology, Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey.
authors.forename: Elnur
authors.initials: E
authors.lastname: Alizade
authors.affiliation: Department of Cardiology, Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey.
authors.forename: Mehmet Mustafa
authors.initials: MM
authors.lastname: Tabakci
authors.affiliation: Department of Cardiology, Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey.
authors.forename: Cüneyt
authors.initials: C
authors.lastname: Toprak
authors.affiliation: Department of Cardiology, Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey.
authors.forename: Birol
authors.initials: B
authors.lastname: Özkan
authors.affiliation: Department of Cardiology, Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey.
authors.forename: Gökhan
authors.initials: G
authors.lastname: Alici
authors.affiliation: Department of Cardiology, Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey.
authors.forename: Ali Metin
authors.initials: AM
authors.lastname: Esen
mesh_terms: D060050:Angina, Stable / Q000097:blood*; D001792:Blood Platelets / Q000378:metabolism*; D002908:Chronic Disease; D003324:Coronary Artery Disease / Q000097:blood* / Q000503:physiopathology; D003326:Coronary Circulation; D054059:Coronary Occlusion / Q000097:blood* / Q000628:therapy; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism*; D008297:Male; D008875:Middle Aged
keywords: atherosclerosis; cardiology; vascular disease