title: [Detection of plasma cofilin protein for diagnosis of lung cancer].
abstract: OBJECTIVE
  To detect serum content of cofilin protein in patients with lung cancer and investigate its clinical value.
  
  
  METHODS
  The serum content of cofilin protein was detected in 30 cases of lung cancer and 30 healthy control subjects using enzyme-linked immunosorbent assay.
  
  
  RESULTS
  The mean serum content of cofilin protein was 0.485∓0.465 ng/ml in patients with lung cancer and 0.203∓0.102 ng/ml in the control subjects, showing a significant difference between them (P<0.05). The content of cofilin protein in patients with stage III and IV lung cancer 0.744∓0.584 ng/ml, significantly higher than that in stage II patients (0.257∓0.126 ng/ml).
  
  
  CONCLUSIONS
  Serum cofilin protein is elevated in patients with lung cancer, especially in cases in advanced stages, suggesting its relation with lung cancer staging.
authors.affiliation: Department of Cardiothoracic Surgery, Shantou Chaonan Mingsheng Hospital; First Affiliated Hospital of Shantou University Medical College, Shantou 515041, China. E-mail: zhengyuju@163.com.
authors.forename: Yuju
authors.initials: Y
authors.lastname: Zheng
authors.forename: Ye
authors.initials: Y
authors.lastname: Fang
authors.forename: Shaojin
authors.initials: S
authors.lastname: Li
authors.forename: Bangxi
authors.initials: B
authors.lastname: Zheng
mesh_terms: D051339:Actin Depolymerizing Factors / Q000097:blood*; D000230:Adenocarcinoma / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging
chemical_list: D051339:Actin Depolymerizing Factors