title: SAX-7 and menorin light the path for dendrite morphogenesis.
abstract: Environmental and cellular cues pattern dendritic growth and direct dendrites to their targets. However, little is known about the signals regulating interactions with the surrounding substrate. Dong et al. and Salzberg et al. now identify a tripartite ligand-receptor complex that conveys cues from the substrate necessary for the patterning of complex dendrites in C. elegans.
authors.affiliation: Department of Physiology and Cellular Biophysics, Columbia University Medical Center, 630 West 168th Street, P&S 12-403, New York, NY 10032, USA.
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Ziegenfuss
authors.forename: Wesley B
authors.initials: WB
authors.lastname: Grueber
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000378:metabolism*; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D003712:Dendrites / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism*; D019006:Neural Cell Adhesion Molecules / Q000378:metabolism*; D055495:Neurogenesis; D009474:Neurons / Q000378:metabolism*
chemical_list: D029742:Caenorhabditis elegans Proteins; C569907:DMA-1 protein, C elegans; C585068:MNR-1 protein, C elegans; D008565:Membrane Proteins; D019006:Neural Cell Adhesion Molecules; C501528:SAX-7 protein, C elegans