title: EZH2 takes the stage when BRCA1 loses.
authors.affiliation: Department of Biochemistry and Molecular Biology; Mayo Clinic College of Medicine; Rochester, MN USA.
authors.forename: Lan
authors.initials: L
authors.lastname: Wang
authors.forename: Haojie
authors.initials: H
authors.lastname: Huang
mesh_terms: D019313:BRCA1 Protein / Q000378:metabolism*; D000071221:Enhancer of Zeste Homolog 2 Protein; D004847:Epithelial Cells / Q000166:cytology / Q000378:metabolism; D005260:Female; D006801:Humans; D042361:Mammary Glands, Human / Q000166:cytology; D063151:Polycomb Repressive Complex 2 / Q000737:chemistry / Q000378:metabolism*; D062085:RNA, Long Noncoding / Q000378:metabolism
chemical_list: D019313:BRCA1 Protein; C561566:HOTAIR long untranslated RNA, human; D062085:RNA, Long Noncoding; C498409:EZH2 protein, human; D000071221:Enhancer of Zeste Homolog 2 Protein; D063151:Polycomb Repressive Complex 2
keywords: BRCA1; EZH2; HOTAIR; PRC2; basal-like breast cancer; cancer therapy; embryonic stem cell; epigenetics; gene silencing; non-coding RNA