title: Structure of active coagulation factor XIII triggered by calcium binding: basis for the design of next-generation anticoagulants.
authors.affiliation: Department of Pharmaceutical Chemistry, Philipps-University, Marbacher Weg 6, 35032 Marburg (Germany).
authors.forename: Martin
authors.initials: M
authors.lastname: Stieler
authors.forename: Johannes
authors.initials: J
authors.lastname: Weber
authors.forename: Martin
authors.initials: M
authors.lastname: Hils
authors.forename: Peter
authors.initials: P
authors.lastname: Kolb
authors.forename: Andreas
authors.initials: A
authors.lastname: Heine
authors.forename: Christian
authors.initials: C
authors.lastname: Büchold
authors.forename: Ralf
authors.initials: R
authors.lastname: Pasternack
authors.forename: Gerhard
authors.initials: G
authors.lastname: Klebe
mesh_terms: D000925:Anticoagulants; D002118:Calcium / Q000737:chemistry*; D015195:Drug Design; D005176:Factor XIII; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D011503:Transglutaminases / Q000737:chemistry*
chemical_list: D000925:Anticoagulants; D005176:Factor XIII; D011503:Transglutaminases; D002118:Calcium
keywords: anticoagulation; calcium; drug design; structure elucidation; transglutaminase