title: Genetics and preterm birth.
abstract: Although the etiology of preterm birth is incompletely understood, phenotype classifications combined with recent technologies such as genome-wide association studies and next-generation sequencing could lead to discovering genotypes associated with preterm birth. Identifying genetic contributions will allow for genetic screening tests to predict or detect pregnancies with potential for preterm birth. In this article we discuss current knowledge regarding phenotype classifications, genotypes, and their associations with preterm birth.
authors.forename: Carolyn M
authors.initials: CM
authors.lastname: Allen
authors.forename: Sandra A
authors.initials: SA
authors.lastname: Founds
mesh_terms: D005260:Female; D005544:Forecasting; D020022:Genetic Predisposition to Disease / Q000209:etiology* / Q000517:prevention & control; D005820:Genetic Testing / Q000592:standards* / Q000639:trends; D055106:Genome-Wide Association Study; D023281:Genomics; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D020380:Needs Assessment; D011247:Pregnancy; D047928:Premature Birth / Q000235:genetics* / Q000517:prevention & control; D014481:United States
keywords: GWAS; NGS; SNPs; genetic screening; parturition; premature birth; preterm birth