title: Nonspecific motility disorders, irritable esophagus, and chest pain.
abstract: This paper presents commentaries on whether Starling's law applies to the esophagus; whether erythromycin affects esophageal motility; the relationship between hypertensive lower esophageal sphincter and vigorous achalasia; whether ethnic- and gender-based norms affect diagnosis and treatment of esophageal motor disorders; health care and epidemiology of chest pain; whether normal pH excludes esophageal pain; the role of high-resolution manometry in noncardiac chest pain; whether pH-impedance should be included in the evaluation of noncardiac chest pain; whether there are there alternative therapeutic options to PPI for treating noncardiac chest pain; and the usefulness of psychological treatment and alternative medicine in noncardiac chest pain.
authors.affiliation: Mech-Sense, Department of Gastroenterology, Aalborg University, Aalborg, Denmark.
authors.forename: Anne Lund
authors.initials: AL
authors.lastname: Krarup
authors.affiliation: Mech-Sense, Department of Gastroenterology, Aalborg University, Aalborg, Denmark.
authors.forename: Donghua
authors.initials: D
authors.lastname: Liao
authors.affiliation: Mech-Sense, Department of Gastroenterology, Aalborg University, Aalborg, Denmark.
authors.forename: Hans
authors.initials: H
authors.lastname: Gregersen
authors.affiliation: Mech-Sense, Department of Gastroenterology, Aalborg University, Aalborg, Denmark.
authors.forename: Asbjørn Mohr
authors.initials: AM
authors.lastname: Drewes
authors.affiliation: Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, Texas.
authors.forename: Reza A
authors.initials: RA
authors.lastname: Hejazi
authors.affiliation: Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, Texas.
authors.forename: Richard W
authors.initials: RW
authors.lastname: McCallum
authors.affiliation: Division of Digestive Diseases and Nutrition, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Vega
authors.affiliation: Fisiopatologia Digestiva, Nuovo Ospedale S. Agostino, Modena, Italy.
authors.forename: Marzio
authors.initials: M
authors.lastname: Frazzoni
authors.affiliation: Fisiopatologia Digestiva, Nuovo Ospedale S. Agostino, Modena, Italy.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Frazzoni
authors.affiliation: Division of Gastroenterology, Johns Hopkins University, Baltimore, Maryland.
authors.forename: John O
authors.initials: JO
authors.lastname: Clarke
authors.affiliation: Mayo College of Medicine, Mayo Clinic, Jacksonville, Florida.
authors.forename: Sami R
authors.initials: SR
authors.lastname: Achem
mesh_terms: D002637:Chest Pain / Q000209:etiology* / Q000503:physiopathology; D004931:Esophageal Achalasia / Q000150:complications / Q000503:physiopathology; D015154:Esophageal Motility Disorders / Q000150:complications* / Q000503:physiopathology; D004947:Esophagus / Q000503:physiopathology*; D006801:Humans; D008365:Manometry
keywords: NCCP; PPI; achalasia; antidepressant