title: Can experience from adults regarding acute liver failure fit children?
abstract: Till date, comparison of clinical characteristics in acute liver failure (ALF) between adults and children has not been performed. In this study, authors retrospectively collected data on adult acute liver failure (AALF) and pediatric acute liver failure (PALF) in seven hospitals in different areas of China from January 2007 through December 2012. A total of 177 AALF cases and 32 PALF cases were eventually included. Several vital clinical variables were significantly different between AALF and PALF, including serum alkaline phosphatase, serum creatinine, serum urea nitrogen, serum lactate dehydrogenase, platelet count, prothrombin activity, international normalized ratio and blood ammonia. It is concluded that experience from AALF could not be proper for PALF.
authors.affiliation: Liver Failure Therapy and Research Center, Beijing 302 Hospital (PLA 302 Hospital), No.100 of West Fourth Ring Middle Road, Beijing, 100039, China, doczhaopan@126.com.
authors.forename: Pan
authors.initials: P
authors.lastname: Zhao
authors.forename: Chunya
authors.initials: C
authors.lastname: Wang
authors.forename: Weiwei
authors.initials: W
authors.lastname: Liu
mesh_terms: D000328:Adult; D000367:Age Factors; D002648:Child; D006801:Humans; D017114:Liver Failure, Acute / Q000097:blood