title: Utilization of carboxymethyl chitosan in cosmetics.
abstract: Carboxymethyl chitosan is a chitosan derivative of the most intensively investigated due to its water solubility in wider pH range compared with the parent compound, thus extended its use in various applications. In this review, different preparation conditions, which resulting in the N- and O-carboxylated chitosan, diverse degree of substitution and water solubility are recapitulated. Five important features of carboxymethyl chitosan from recent studies, which are moisture absorption-retention, anti-microbial properties, antioxidant capacities, delivery system and emulsion stabilization, have been centred and emphasized for cosmetic utilization. Additionally, cytotoxicity information has been inclusively incorporated to ensure its safety in application.
authors.affiliation: School of Cosmetic Science, Mae Fah Luang University, Muang, Chiangrai, 57100, Thailand.
authors.forename: A
authors.initials: A
authors.lastname: Jimtaisong
authors.affiliation: School of Cosmetic Science, Mae Fah Luang University, Muang, Chiangrai, 57100, Thailand.
authors.forename: N
authors.initials: N
authors.lastname: Saewan
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D048271:Chitosan / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D003358:Cosmetics / Q000737:chemistry*; D006801:Humans
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D003358:Cosmetics; C514968:carboxymethyl-chitosan; D048271:Chitosan
keywords: anti-microbial; carboxymethyl chitosan; delivery system; emulsion stabilizer; moisture retention