title: Is there a difference in the prevalence of gastroesophageal reflux disease between peritoneal dialysis and hemodialysis patients?
abstract: OBJECTIVE
  Gastroesophageal reflux disease (GERD) is a common upper gastrointestinal disorder in patients with chronic kidney disease (CKD). However, little is known about the prevalence of GERD in dialysis patients. The aim of the present study was to investigate the difference in the prevalence of GERD in peritoneal dialysis and hemodialysis patients.
  
  
  METHODS
  From July 2010 to August 2011, peritoneal dialysis patients (n=30) and hemodialysis patients (n=38) were enrolled. The prevalences of GERD were assessed at a single center with endoscopic findings and interviews using a questionnaire. Also, risk factors of GERD were evaluated.
  
  
  RESULTS
  The prevalences of GERD in peritoneal dialysis and hemodialysis patients were 33.3% and 39.5% (p=0.748), respectively. The prevalences of erosive reflux esophagitis (ERD) in peritoneal dialysis and hemodialysis patients were 16.7% and 23.7% (p=0.477), respectively. The prevalences of nonerosive reflux disease (NERD) in peritoneal dialysis and hemodialysis patients were 16.7% and 13.2% (p=0.685), respectively. The prevalences of GERD, ERD and NERD were higher than those of the general population. The risk factor for GERD was age in hemodialysis patients.
  
  
  CONCLUSIONS
  The prevalence of GERD in dialysis patients was higher than that in the general population. However, there was no significant difference between peritoneal dialysis and hemodialysis patients.
authors.affiliation: Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea.
authors.forename: Hyun Jung
authors.initials: HJ
authors.lastname: Song
authors.forename: Sun Moon
authors.initials: SM
authors.lastname: Kim
authors.forename: Yu Mi
authors.initials: YM
authors.lastname: Lee
authors.forename: Jung Ah
authors.initials: JA
authors.lastname: Hwang
authors.forename: Kyung Min
authors.initials: KM
authors.lastname: Moon
authors.forename: Chang Gi
authors.initials: CG
authors.lastname: Moon
authors.forename: Hoon Sup
authors.initials: HS
authors.lastname: Koo
authors.forename: Kyung Ho
authors.initials: KH
authors.lastname: Song
authors.forename: Yong Seok
authors.initials: YS
authors.lastname: Kim
authors.forename: Tae Hee
authors.initials: TH
authors.lastname: Lee
authors.forename: Kyu Chan
authors.initials: KC
authors.lastname: Huh
authors.forename: Young Woo
authors.initials: YW
authors.lastname: Choi
authors.forename: Young Woo
authors.initials: YW
authors.lastname: Kang
authors.forename: Won Min
authors.initials: WM
authors.lastname: Hwang
authors.forename: Sung Ro
authors.initials: SR
authors.lastname: Yun
mesh_terms: D000368:Aged; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D004942:Esophagitis, Peptic / Q000150:complications / Q000453:epidemiology; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications / Q000453:epidemiology*; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000150:complications; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000706:statistics & numerical data; D015995:Prevalence; D006435:Renal Dialysis / Q000706:statistics & numerical data; D012307:Risk Factors; D012907:Smoking; D011795:Surveys and Questionnaires