title: Fluid structural analysis of human cerebral aneurysm using their own wall mechanical properties.
abstract: Computational Structural Dynamics (CSD) simulations, Computational Fluid Dynamics (CFD) simulation, and Fluid Structure Interaction (FSI) simulations were carried out in an anatomically realistic model of a saccular cerebral aneurysm with the objective of quantifying the effects of type of simulation on principal fluid and solid mechanics results. Eight CSD simulations, one CFD simulation, and four FSI simulations were made. The results allowed the study of the influence of the type of material elements in the solid, the aneurism's wall thickness, and the type of simulation on the modeling of a human cerebral aneurysm. The simulations use their own wall mechanical properties of the aneurysm. The more complex simulation was the FSI simulation completely coupled with hyperelastic Mooney-Rivlin material, normal internal pressure, and normal variable thickness. The FSI simulation coupled in one direction using hyperelastic Mooney-Rivlin material, normal internal pressure, and normal variable thickness is the one that presents the most similar results with respect to the more complex FSI simulation, requiring one-fourth of the calculation time.
authors.affiliation: Department of Mechanical Engineering, Universidad de Chile, 8370448 Santiago, Chile.
authors.forename: Alvaro
authors.initials: A
authors.lastname: Valencia
authors.forename: Patricio
authors.initials: P
authors.lastname: Burdiles
authors.forename: Miguel
authors.initials: M
authors.lastname: Ignat
authors.forename: Jorge
authors.initials: J
authors.lastname: Mura
authors.forename: Eduardo
authors.initials: E
authors.lastname: Bravo
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Rivera
authors.forename: Juan
authors.initials: J
authors.lastname: Sordo
mesh_terms: D001696:Biomechanical Phenomena; D001698:Biomedical Engineering / Q000295:instrumentation; D003198:Computer Simulation; D055119:Elastic Modulus; D020342:Finite Element Analysis; D006801:Humans; D057446:Hydrodynamics; D021621:Imaging, Three-Dimensional; D002532:Intracranial Aneurysm / Q000473:pathology / Q000503:physiopathology*; D016014:Linear Models; D008955:Models, Cardiovascular