title: The impact of Helicobacter pylori on the complications of laparoscopic sleeve gastrectomy.
abstract: Helicobacter pylori (H. pylori) is a very common bacterium present in the gastric tissue of up to 50 % of people, and the mucosal damage it causes can predispose to multiple comorbid conditions. This study aims to observe the prevalence of H. pylori infection in patients undergoing laparoscopic sleeve gastrectomy (LSG) and its correlation with postoperative complications. A retrospective study was done on the gastric pathology specimen results of 682 patients who underwent LSG at Amiri Hospital from 2008 to 2012. Symptomatic patients had preoperative upper gastrointestinal endoscopies (UGIEs) based on the decision of the treating surgeon, along with campylobacter-like organism test (CLO test) for H. pylori detection. The intraoperatively excised gastric specimen was sent for histopathological assessment of H. pylori, and the patients were followed up for complications. Of the 682 patients, 629 (92.2 %) were found to be H. pylori negative intraoperatively, while 53 (7.8 %) were positive. A total of 32 (4.7 %) patients were found to have postoperative complications, of which 2 (6.3 %) had H. pylori intraoperatively. No statistical significance (p = 0.71), however, was seen between the overall complication rate and H. pylori. Specifically, there were five (0.7 %) cases of leak and eight (1.2 %) cases of neuropathy, both of which were not significantly associated with H. pylori (p = 0.33 and p = 0.12, respectively). All the other complications had no evidence of H. pylori. There appears to be no association between H. pylori infection and post-LSG complications.
authors.affiliation: Department of Surgery, Amiri Hospital, Kuwait Ministry of Health, Kuwait, Kuwait.
authors.forename: Sulaiman
authors.initials: S
authors.lastname: Almazeedi
authors.forename: Salman
authors.initials: S
authors.lastname: Al-Sabah
authors.forename: Dheidan
authors.initials: D
authors.lastname: Alshammari
authors.forename: Shamlan
authors.initials: S
authors.lastname: Alqinai
authors.forename: Ahmed
authors.initials: A
authors.lastname: Al-Mulla
authors.forename: Ahmed
authors.initials: A
authors.lastname: Al-Murad
authors.forename: Khaled
authors.initials: K
authors.lastname: Al-Enezi
authors.forename: Talib
authors.initials: T
authors.lastname: Jumaa
mesh_terms: D016099:Endoscopy, Gastrointestinal; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects; D005753:Gastric Mucosa / Q000382:microbiology*; D016481:Helicobacter Infections / Q000150:complications* / Q000382:microbiology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D009767:Obesity, Morbid / Q000150:complications / Q000382:microbiology*; D011300:Preoperative Care; D015995:Prevalence; D012189:Retrospective Studies; D016896:Treatment Outcome