title: TERT promoter mutations rather than methylation are the main mechanism for TERT upregulation in adult gliomas.
authors.affiliation: Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Arita
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Narita
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Takami
authors.forename: Shintaro
authors.initials: S
authors.lastname: Fukushima
authors.forename: Yuko
authors.initials: Y
authors.lastname: Matsushita
authors.forename: Akihiko
authors.initials: A
authors.lastname: Yoshida
authors.forename: Yasuji
authors.initials: Y
authors.lastname: Miyakita
authors.forename: Makoto
authors.initials: M
authors.lastname: Ohno
authors.forename: Soichiro
authors.initials: S
authors.lastname: Shibui
authors.forename: Koichi
authors.initials: K
authors.lastname: Ichimura
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000235:genetics*; D005910:Glioma / Q000235:genetics*; D006801:Humans; D008745:Methylation; D009154:Mutation; D011401:Promoter Regions, Genetic; D019098:Telomerase / Q000235:genetics*; D015854:Up-Regulation
chemical_list: C509186:TERT protein, human; D019098:Telomerase