title: The estimation of glomerular filtration rate in type 2 diabetic patients may depend on the equation used.
abstract: BACKGROUND
  The aim of this study was to compare the estimation of glomerular filtration rate (GFR) in type 2 diabetes mellitus (DM) outpatients.
  
  
  METHODS
  The study included 1686 subjects, aged 68±10 years. GFR was evaluated with five different equations: GFRMDRD186, GFRMDRD175, GFRCKD-EPI, GFRMAYO, GFRC-G.
  
  
  RESULTS
  GFR was lower than 60 ml min-1 kg-1 in 456 patients (27%) by GFRMDRD186, in 531 (31.5%) by GFRMDRD175, in 504 (30%) by GFRCKD-EPI, in 433 (26%) by GFRC-G, and in 255 (15%) by GFRMAYO. The mean differences in measuring GFR with the different formulae ranged from 1.03±6.20 to -14.5±11.9 ml min-1 1.73 m2-1.
  
  
  CONCLUSIONS
  The evaluation of GFR with different formulae in type 2 DM patients may identify different chronic kidney disease (CKD) stages. Physicians could take advantage by the knowledge of the formula used for evaluation of renal function, for a better interpretation of values and a more appropriate use in the everyday clinical practice.
authors.affiliation: Institute of Clinical Medicine, School of Medicine, University Hospital of Ferrara, Ferrara, Italy. f.fabbian@ospfe.it.
authors.forename: F
authors.initials: F
authors.lastname: Fabbian
authors.forename: M
authors.initials: M
authors.lastname: Pala
authors.forename: M
authors.initials: M
authors.lastname: Monesi
authors.forename: A
authors.initials: A
authors.lastname: De Giorgi
authors.forename: A
authors.initials: A
authors.lastname: Mallozzi Menegatti
authors.forename: F
authors.initials: F
authors.lastname: Tomasi
authors.forename: F
authors.initials: F
authors.lastname: Portaluppi
authors.forename: R
authors.initials: R
authors.lastname: Manfredini
mesh_terms: D000368:Aged; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D051436:Renal Insufficiency, Chronic / Q000175:diagnosis