title: Pre-multidrug-resistant Mycobacterium tuberculosis Beijing strain associated with disseminated tuberculosis in a pet dog.
abstract: Resistance to isoniazid, ethambutol, and streptomycin was detected in a Mycobacterium tuberculosis strain, belonging to the Beijing family lineage, isolated from two nodule exudates of a Yorkshire terrier with generalized tuberculosis. This report alerts medical practitioners to the risk of dissemination of pre-multidrug-resistant tuberculosis (preMDR-TB) through exposure to M. tuberculosis-shedding pets.
authors.affiliation: INIAV, I.P.-Instituto Nacional de Investigação Agrária e Veterinária, Unidade Estratégica de Produção e Saúde Animal, Lisbon, Portugal.
authors.forename: Ana
authors.initials: A
authors.lastname: Botelho
authors.forename: João
authors.initials: J
authors.lastname: Perdigão
authors.forename: Ana
authors.initials: A
authors.lastname: Canto
authors.forename: Teresa
authors.initials: T
authors.lastname: Albuquerque
authors.forename: Nuno
authors.initials: N
authors.lastname: Leal
authors.forename: Rita
authors.initials: R
authors.lastname: Macedo
authors.forename: Isabel
authors.initials: I
authors.lastname: Portugal
authors.forename: Mónica V
authors.initials: MV
authors.lastname: Cunha
mesh_terms: D000818:Animals; D000995:Antitubercular Agents / Q000494:pharmacology*; D004283:Dog Diseases / Q000175:diagnosis* / Q000382:microbiology*; D004285:Dogs; D024901:Drug Resistance, Multiple, Bacterial; D004977:Ethambutol / Q000494:pharmacology; D007538:Isoniazid / Q000494:pharmacology; D008297:Male; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D057805:Pets; D013307:Streptomycin / Q000494:pharmacology; D014388:Tuberculosis, Lymph Node / Q000382:microbiology / Q000662:veterinary*
chemical_list: D000995:Antitubercular Agents; D004977:Ethambutol; D007538:Isoniazid; D013307:Streptomycin