title: Feasibility of semiautomated MR volumetry using gadoxetic acid-enhanced MRI at hepatobiliary phase for living liver donors.
abstract: OBJECTIVE
  To assess the feasibility of semiautomated MR volumetry using gadoxetic acid-enhanced MRI at the hepatobiliary phase compared with manual CT volumetry.
  
  
  METHODS
  Forty potential live liver donor candidates who underwent MR and CT on the same day, were included in our study. Semiautomated MR volumetry was performed using gadoxetic acid-enhanced MRI at the hepatobiliary phase. We performed the quadratic MR image division for correction of the bias field inhomogeneity. With manual CT volumetry as the reference standard, we calculated the average volume measurement error of the semiautomated MR volumetry. We also calculated the mean of the number and time of the manual editing, edited volume, and total processing time.
  
  
  RESULTS
  The average volume measurement errors of the semiautomated MR volumetry were 2.35% ± 1.22%. The average values of the numbers of editing, operation times of manual editing, edited volumes, and total processing time for the semiautomated MR volumetry were 1.9 ± 0.6, 8.1 ± 2.7 s, 12.4 ± 8.8 mL, and 11.7 ± 2.9 s, respectively.
  
  
  CONCLUSIONS
  Semiautomated liver MR volumetry using hepatobiliary phase gadoxetic acid-enhanced MRI with the quadratic MR image division is a reliable, easy, and fast tool to measure liver volume in potential living liver donors.
authors.affiliation: School of Computer Science & Engineering, Soongsil University, Seoul, Korea.
authors.forename: Jeongjin
authors.initials: J
authors.lastname: Lee
authors.forename: Kyoung Won
authors.initials: KW
authors.lastname: Kim
authors.forename: So Yeon
authors.initials: SY
authors.lastname: Kim
authors.forename: Bohyoung
authors.initials: B
authors.lastname: Kim
authors.forename: So Jung
authors.initials: SJ
authors.lastname: Lee
authors.forename: Hyoung Jung
authors.initials: HJ
authors.lastname: Kim
authors.forename: Jong Seok
authors.initials: JS
authors.lastname: Lee
authors.forename: Moon Gyu
authors.initials: MG
authors.lastname: Lee
authors.forename: Gi-Won
authors.initials: GW
authors.lastname: Song
authors.forename: Shin
authors.initials: S
authors.lastname: Hwang
authors.forename: Sung-Gyu
authors.initials: SG
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D003287:Contrast Media; D005240:Feasibility Studies; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007472:Iohexol / Q000031:analogs & derivatives; D016031:Liver Transplantation; D019520:Living Donors; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; C073590:gadolinium ethoxybenzyl DTPA; D007472:Iohexol; C038192:iopromide; D019786:Gadolinium DTPA
keywords: Semiautomated liver volumetry; computer-aided diagnosis; gadoxetic acid-enhanced MR; hepatobiliary phase