title: Synthesis of inosine 6-phosphate diesters via phosphitylation of the carbonyl oxygen.
abstract: Inosine derivatives bearing a phosphodiester group at the O(6)-position of the nucleobase were synthesized via phosphitylation of the carbonyl oxygen using phosphoramidites activated by non-nucleophilic acidic activators.
authors.affiliation: Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan. oka@gifu-u.ac.jp.
authors.forename: Natsuhisa
authors.initials: N
authors.lastname: Oka
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Morita
authors.forename: Yuta
authors.initials: Y
authors.lastname: Itakura
authors.forename: Kaori
authors.initials: K
authors.lastname: Ando
mesh_terms: D001388:Aziridines / Q000737:chemistry; D004952:Esters / Q000737:chemistry; D019271:Hypoxanthine / Q000737:chemistry; D007292:Inosine Nucleotides / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry; D010100:Oxygen / Q000737:chemistry
chemical_list: D001388:Aziridines; D004952:Esters; D007292:Inosine Nucleotides; D008698:Mesylates; D019271:Hypoxanthine; D010100:Oxygen