title: Pseudothrombocytopenia observed with ethylene diamine tetra acetate and citrate anticoagulants, resolved using 37°C incubation and Kanamycin.
abstract: Pseudothrombocytopenia (PTP) is defined by falsely low platelet counts on automated analyzers caused by in vitro phenomena including large platelet aggregates in blood samples. Diagnosis and resolution of PTP is crucial as it can lead to unwarranted interventions. We discuss a case of PTP in a pre-surgical setting, which was resolved using 37°C incubation and Kanamycin.
authors.affiliation: Department of Transfusion Medicine and Immunohaematology, Christian Medical College, Vellore, Tamil Nadu, India.
authors.forename: Vandana
authors.initials: V
authors.lastname: Kamath
authors.forename: Parimal
authors.initials: P
authors.lastname: Sarda
authors.forename: Mary Purna
authors.initials: MP
authors.lastname: Chacko
authors.forename: Usha
authors.initials: U
authors.lastname: Sitaram
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000378:metabolism*; D019343:Citric Acid / Q000378:metabolism*; D003951:Diagnostic Errors; D004492:Edetic Acid / Q000378:metabolism*; D006801:Humans; D007612:Kanamycin / Q000378:metabolism*; D008297:Male; D013048:Specimen Handling / Q000379:methods*; D013696:Temperature; D013921:Thrombocytopenia / Q000175:diagnosis*
chemical_list: D000925:Anticoagulants; D019343:Citric Acid; D007612:Kanamycin; D004492:Edetic Acid