title: CKD is associated with recurrent ischemia but not with hemorrhagic transformation in acute ischemic stroke patients.
abstract: BACKGROUND
  We investigated the associations of Recurrent Ischemic Stroke (RIS) and Hemorrhagic Transformation (HT) with CKD in acute ischemic stroke patients.
  
  
  METHODS
  The subjects were 160 patients, divided into two groups: with eGFR <60 mL/min/1.73 m2 (CKD), with eGFR ≥60 mL/min/1.73 m2 (without CKD).
  
  
  RESULTS
  Subjects having DM (p = 0.018), CKD (p = 0.025) and treated with ACEI/ARB (p = 0.039) revealed association with RIS. Regression analysis disclosed only CKD (p = 0.04). Carotid artery stenosis (p = 0.030) and serum calcium levels (p = 0.013) showed significant association with HT.
  
  
  CONCLUSIONS
  Our results disclosed that CKD could be a risk factor for RIS. There is no relation between CKD and HT.
authors.affiliation: Department of Nephrology , and.
authors.forename: Hasan
authors.initials: H
authors.lastname: Micozkadioglu
authors.forename: Ruya
authors.initials: R
authors.lastname: Ozelsancak
authors.forename: Semih
authors.initials: S
authors.lastname: Giray
authors.forename: Zulfikar
authors.initials: Z
authors.lastname: Arlier
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000150:complications*; D002118:Calcium / Q000097:blood; D016893:Carotid Stenosis / Q000150:complications; D002543:Cerebral Hemorrhage / Q000097:blood / Q000209:etiology*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D051436:Renal Insufficiency, Chronic / Q000150:complications* / Q000503:physiopathology; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000150:complications*
chemical_list: D002118:Calcium