title: Effects of estrogen fluctuation during the menstrual cycle on the response to stretch-shortening exercise in females.
abstract: The aim of this study was to investigate whether variation in estrogen levels during the menstrual cycle influences susceptibility to exercise-induced muscle damage after stretch-shortening cycle exercise. Physically active women (n = 18; age = 20.2 ± 1.7 yr) participated in this research. The subjects performed one session of 100 maximal drop jumps on day 1 or 2 of the follicular phase and another identical session on day 1 or 2 of the ovulatory phase; the order of the sessions was randomized. Quadriceps femoris muscle peak torque evoked by electrical stimulation and maximal voluntary contraction, muscle pain, and CK activity were measured before and at various times up to 72 h after exercise. It was found that the high estrogen level during the ovulatory phase might be related to an earlier return to baseline muscle strength after strenuous stretch-shortening cycle exercise in that phase compared with the follicular phase. The estrogen effect appears to be highly specific to the damaged site because the differences in most EIMD markers (CK, soreness, and low-frequency fatigue) between the two menstrual cycle phases were small.
authors.affiliation: Department of Applied Physiology and Kinesiotherapy, Lithuanian Sports University, Sporto 6, 44221 Kaunas, Lithuania.
authors.forename: Saulė
authors.initials: S
authors.lastname: Sipavičienė
authors.forename: Laura
authors.initials: L
authors.lastname: Daniusevičiutė
authors.forename: Irina
authors.initials: I
authors.lastname: Klizienė
authors.forename: Sigitas
authors.initials: S
authors.lastname: Kamandulis
authors.forename: Albertas
authors.initials: A
authors.lastname: Skurvydas
mesh_terms: D000328:Adult; D004967:Estrogens / Q000097:blood*; D005260:Female; D006801:Humans; D008597:Menstrual Cycle; D053580:Muscle Strength / Q000502:physiology; D018482:Muscle, Skeletal / Q000502:physiology; D059385:Plyometric Exercise / Q000009:adverse effects*; D019415:Torque; D055815:Young Adult
chemical_list: D004967:Estrogens