title: Carcinosarcoma of the uterine corpus on 18F-FDG PET/CT in a postmenopausal woman with elevated AFP.
abstract: Uterine carcinosarcoma (termed malignant mixed müllerian tumor) is a rare neoplasm of the uterus with a poor prognosis. There have been very few cases in the literature describing the PET/CT findings of uterine carcinosarcoma. We report a case of tissue-proven carcinosarcoma of the uterine corpus in a 65-year-old woman with elevated serum alpha-fetoprotein (AFP), whose 18F-FDG PET/CT showed a 10.3-cm mass in the uterus with uneven high FDG uptake. The SUVmax was 12.8. After surgery, the patient received 6 courses of chemotherapy, and the serum levels of AFP decreased to reference range.
authors.affiliation: From the Department of Nuclear Medicine, the Fourth Hospital of Wuxi, Wuxi, Jiangsu, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Chen
authors.forename: Chunjing
authors.initials: C
authors.lastname: Yu
authors.forename: Xuyang
authors.initials: X
authors.lastname: You
authors.forename: Boming
authors.initials: B
authors.lastname: Mi
authors.forename: Weixing
authors.initials: W
authors.lastname: Wan
mesh_terms: D000368:Aged; D002296:Carcinosarcoma / Q000097:blood / Q000000981:diagnostic imaging*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D018200:Mixed Tumor, Mullerian / Q000097:blood / Q000000981:diagnostic imaging*; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D017698:Postmenopause; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D014594:Uterine Neoplasms / Q000097:blood / Q000000981:diagnostic imaging*; D000509:alpha-Fetoproteins / Q000378:metabolism*
chemical_list: D019275:Radiopharmaceuticals; D000509:alpha-Fetoproteins; D019788:Fluorodeoxyglucose F18