title: Methotrexate toxicity induced by ciprofloxacin leading to psoriatic plaque ulceration: a case report.
abstract: We present the case of a 90-year-old woman with psoriasis vulgaris who had been treated with methotrexate for many years. The patient presented with psoriatic plaque ulcerations uniquely limited to the active border as well as acute oral ulcerations and severe gastrointestinal upset after undergoing a course of ciprofloxacin for treatment of a bacterial infection.
authors.affiliation: 515 Spruce St, San Francisco, CA 94118, USA. fkamangar@gmail.com.
authors.forename: Faranak
authors.initials: F
authors.lastname: Kamangar
authors.forename: Timothy G
authors.initials: TG
authors.lastname: Berger
authors.forename: Nasim
authors.initials: N
authors.lastname: Fazel
authors.forename: John Y M
authors.initials: JY
authors.lastname: Koo
mesh_terms: D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy; D002939:Ciprofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004347:Drug Interactions; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D011565:Psoriasis / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents; D002939:Ciprofloxacin; D008727:Methotrexate