title: Failure of fourth-generation enzyme immunoassay in HIV screening and plasma HIV-1 RNA detection in recent high-risk behavior.
abstract: Acute HIV infection was not detected in a young man presenting symptoms of sexual disease infection using fourth-generation screening tests combining HIV-specific antibody and p24 antigen. Detection of plasma HIV-1 RNA concomitant with screening tests may be proposed in individuals presenting with a symptomatic sexually transmitted infection.
authors.affiliation: Laboratoire de Microbiologie, AP-HP-Hôpital Saint Louis, Paris, France.
authors.forename: Sarah
authors.initials: S
authors.lastname: Maylin
authors.forename: Sébastien
authors.initials: S
authors.lastname: Fouéré
authors.forename: François
authors.initials: F
authors.lastname: Simon
authors.forename: Constance
authors.initials: C
authors.lastname: Delaugerre
mesh_terms: D003951:Diagnostic Errors; D015483:HIV Antibodies / Q000097:blood; D015488:HIV Antigens / Q000097:blood; D015658:HIV Infections / Q000175:diagnosis*; D015497:HIV-1 / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D008297:Male; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D012367:RNA, Viral / Q000097:blood; D012309:Risk-Taking; D014773:Virology / Q000379:methods*; D055815:Young Adult
chemical_list: D015483:HIV Antibodies; D015488:HIV Antigens; D012367:RNA, Viral