title: C3 glomerulopathy: consensus report.
abstract: C3 glomerulopathy is a recently introduced pathological entity whose original definition was glomerular pathology characterized by C3 accumulation with absent or scanty immunoglobulin deposition. In August 2012, an invited group of experts (comprising the authors of this document) in renal pathology, nephrology, complement biology, and complement therapeutics met to discuss C3 glomerulopathy in the first C3 Glomerulopathy Meeting. The objectives were to reach a consensus on: the definition of C3 glomerulopathy, appropriate complement investigations that should be performed in these patients, and how complement therapeutics should be explored in the condition. This meeting report represents the current consensus view of the group.
authors.affiliation: Centre for Complement and Inflammation Research, Imperial College London, London, UK.
authors.forename: Matthew C
authors.initials: MC
authors.lastname: Pickering
authors.forename: Vivette D
authors.initials: VD
authors.lastname: D'Agati
authors.forename: Carla M
authors.initials: CM
authors.lastname: Nester
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Smith
authors.forename: Mark
authors.initials: M
authors.lastname: Haas
authors.forename: Gerald B
authors.initials: GB
authors.lastname: Appel
authors.forename: Charles E
authors.initials: CE
authors.lastname: Alpers
authors.forename: Ingeborg M
authors.initials: IM
authors.lastname: Bajema
authors.forename: Camille
authors.initials: C
authors.lastname: Bedrosian
authors.forename: Michael
authors.initials: M
authors.lastname: Braun
authors.forename: Mittie
authors.initials: M
authors.lastname: Doyle
authors.forename: Fadi
authors.initials: F
authors.lastname: Fakhouri
authors.forename: Fernando C
authors.initials: FC
authors.lastname: Fervenza
authors.forename: Agnes B
authors.initials: AB
authors.lastname: Fogo
authors.forename: Véronique
authors.initials: V
authors.lastname: Frémeaux-Bacchi
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Gale
authors.forename: Elena
authors.initials: E
authors.lastname: Goicoechea de Jorge
authors.forename: Gene
authors.initials: G
authors.lastname: Griffin
authors.forename: Claire L
authors.initials: CL
authors.lastname: Harris
authors.forename: V Michael
authors.initials: VM
authors.lastname: Holers
authors.forename: Sally
authors.initials: S
authors.lastname: Johnson
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Lavin
authors.forename: Nicholas
authors.initials: N
authors.lastname: Medjeral-Thomas
authors.forename: B
authors.initials: B
authors.lastname: Paul Morgan
authors.forename: Cynthia C
authors.initials: CC
authors.lastname: Nast
authors.forename: Laure-Hélène
authors.initials: LH
authors.lastname: Noel
authors.forename: D Keith
authors.initials: DK
authors.lastname: Peters
authors.forename: Santiago
authors.initials: S
authors.lastname: Rodríguez de Córdoba
authors.forename: Aude
authors.initials: A
authors.lastname: Servais
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Sethi
authors.forename: Wen-Chao
authors.initials: WC
authors.lastname: Song
authors.forename: Paul
authors.initials: P
authors.lastname: Tamburini
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Thurman
authors.forename: Michael
authors.initials: M
authors.lastname: Zavros
authors.forename: H Terence
authors.initials: HT
authors.lastname: Cook
mesh_terms: D035843:Biomedical Research; D001706:Biopsy; D003176:Complement C3 / Q000032:analysis*; D003299:Cooperative Behavior; D005921:Glomerulonephritis / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D006801:Humans; D007391:International Cooperation; D007678:Kidney Glomerulus / Q000276:immunology* / Q000473:pathology; D011237:Predictive Value of Tests; D011379:Prognosis
chemical_list: C038245:C3 protein, human; D003176:Complement C3