title: Direct C-2 arylation of 7-azaindoles: chemoselective access to multiarylated derivatives.
abstract: Pd-catalyzed direct C-H arylation of N-methyl-7-azaindole at the C-2 position by diverse arylboronic acids was achieved at room temperature. The method is general and was applied in chemoselective synthesis of multiarylated 7-azaindole derivatives bearing three different aryl groups at the 2, 3, and 5 positions.
authors.affiliation: Academy of Scientific and Innovative Research (AcSIR) and Medicinal Chemistry Division, Indian Institute of Integrative Medicine(CSIR) , Jammu 180001, India.
authors.forename: Prakash
authors.initials: P
authors.lastname: Kannaboina
authors.forename: K
authors.initials: K
authors.lastname: Anilkumar
authors.forename: S
authors.initials: S
authors.lastname: Aravinda
authors.forename: Ram A
authors.initials: RA
authors.lastname: Vishwakarma
authors.forename: Parthasarathi
authors.initials: P
authors.lastname: Das
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D001897:Boronic Acids; D007211:Indoles; C587704:N-methyl-7-azaindole; D010165:Palladium