title: Determination of amino acid enantiopurity and absolute configuration: synergism between configurationally labile metal-based receptors and dynamic covalent interactions.
abstract: Reliable determination of the enantiomeric excess of free amino acids can be obtained by measuring the induced circular dichroism of a multicomponent assembly formed by a modified tris(2-pyridylmethyl)amine ligand, a zinc salt, and the amino acid of interest. The systems furnish reliable information for all natural amino acids.
authors.affiliation: Dipartimento di Scienze Chimiche, Università degli Studi di Padova, Via Marzolo 1, 35131 Padova (Italy).
authors.forename: Francesca A
authors.initials: FA
authors.lastname: Scaramuzzo
authors.forename: Giulia
authors.initials: G
authors.lastname: Licini
authors.forename: Cristiano
authors.initials: C
authors.lastname: Zonta
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D002942:Circular Dichroism; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism; D015032:Zinc / Q000737:chemistry*
chemical_list: D000596:Amino Acids; D011725:Pyridines; C431843:tris(2-pyridylmethyl)amine; D015032:Zinc
keywords: amino acids; chirality; circular dichroism; configuration determination; ligands; molecular recognition