title: Obesity and CKD progression: hard facts on fat CKD patients.
abstract: Obesity is a worldwide epidemic and there is compelling evidence that excess fat is closely associated with chronic kidney disease (CKD) and end-stage kidney failure. In this review, we will describe some important mechanisms related with the pathogenesis and treatment of CKD in obesity by emphasizing the role of excess fat in renal haemodynamic and structural alterations.
authors.affiliation: Nephrology, Dialysis and Transplantation Unit & CNR-IBIM, Reggio Calabria, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Mallamaci
authors.forename: Giovanni
authors.initials: G
authors.lastname: Tripepi
mesh_terms: D050154:Adiposity; D018450:Disease Progression; D006801:Humans; D009765:Obesity / Q000150:complications*; D051436:Renal Insufficiency, Chronic / Q000209:etiology* / Q000473:pathology; D012307:Risk Factors
keywords: body mass index; chronic kidney disease; obesity