title: The outcome of different post-thawed culture period in frozen-thawed embryo transfer cycle.
abstract: OBJECTIVE
  To study the influence of post-thawed culture (2-4 h and 20-24 h) on the outcome of frozen-thawed embryo transfer (FET) cycle.
  
  
  METHODS
  In this retrospective study, a total of 1,353 patients were undergoing the FET treatment at the reproductive medical center between June 2010 and July 2012. 3,398 frozen-thawed embryos were divided in two study groups, depending on their post-thawed culture period: short culture (2-4 h) group and long culture (20-24 h) group. Groups were compared including clinical pregnancy rate, implantation rate, spontaneous abortion rate, ectopic pregnancy rate, multiple pregnancy rate, live birth rate and birth weight.
  
  
  RESULTS
  When embryos including at least one grade I embryo after thawed transferred, the clinical pregnancy rate, implantation rate, multiple pregnancy rate, abortion rate, ectopic pregnancy rate, live birth rate and birth weight were similar in the short culture group compared with these in the long culture group.
  
  
  CONCLUSIONS
  The outcomes of the two approaches (short culture and long culture) are no different in FET cycles.
authors.affiliation: Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Baiyundadaobei Road, Baiyun District, Guangzhou, 510515, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Guo
authors.forename: Chen
authors.initials: C
authors.lastname: Luo
authors.forename: Song
authors.initials: S
authors.lastname: Quan
authors.forename: Leining
authors.initials: L
authors.lastname: Chen
authors.forename: Hong
authors.initials: H
authors.lastname: Li
authors.forename: Yangchun
authors.initials: Y
authors.lastname: Guo
authors.forename: Zhiming
authors.initials: Z
authors.lastname: Han
authors.forename: Xianghong
authors.initials: X
authors.lastname: Ou
mesh_terms: D001723:Birth Rate; D015925:Cryopreservation; D010064:Embryo Implantation; D004624:Embryo Transfer / Q000379:methods*; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D011247:Pregnancy; D018873:Pregnancy Rate