title: Novel nanomaterials used for sample preparation for protein analysis.
abstract: Sample preparation is of vital importance for proteomic analysis because of the high complexity of biological samples. The rapid development of novel nanomaterials with various compositions, morphologies, and proper surface modifications provides a category of powerful tools for the sample preparation for protein analysis. In this paper, we have summarized recent progresses for the applications of novel nanomaterials in sample preparation for the analysis of proteomes, especially for phosphoproteomes, glycoproteomes, and peptidoms. Several kinds of novel nanomaterials were also discussed for their use in other kinds of proteomics analysis.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Institute of Analytical Chemistry, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.
authors.forename: Liping
authors.initials: L
authors.lastname: Li
authors.forename: Linnan
authors.initials: L
authors.lastname: Xu
authors.forename: Ze
authors.initials: Z
authors.lastname: Li
authors.forename: Yu
authors.initials: Y
authors.lastname: Bai
authors.forename: Huwei
authors.initials: H
authors.lastname: Liu
mesh_terms: D053000:Analytic Sample Preparation Methods; D000818:Animals; D002846:Chromatography, Affinity; D054794:Glycomics / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D049329:Nanostructures / Q000737:chemistry*; D010750:Phosphoproteins / Q000032:analysis; D040901:Proteomics / Q000295:instrumentation / Q000379:methods*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D010750:Phosphoproteins