title: [A case of Crohn's disease accompanied by Peutz-Jeghers syndrome].
abstract: Peutz-Jeghers syndrome is an autosomal dominant inherited disorder characterized by multiple gastrointestinal hamartomatous polyps and mucocutaneous pigmentation. Peutz-Jeghers syndrome has an incidence of approximately 1 in 25,000 to 300,000 births. Crohn's disease is a chronic inflammatory bowel disease that typically manifests as regional enteritis with its incidence ranging from 3.1 to 14.6 cases per 100,000 person-years in North America. Herein, we report a case of a 30-year-old male patient who had both Peutz-Jeghers syndrome and Crohn's disease. We believe that this is the first case in Korea and the second report in the English literatures on Peutz-Jeghers syndrome coincidentally accompanied by Crohn's disease.
authors.affiliation: Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea.
authors.forename: Yoo Jin
authors.initials: YJ
authors.lastname: Um
authors.forename: Sun Moon
authors.initials: SM
authors.lastname: Kim
authors.forename: Jin Sil
authors.initials: JS
authors.lastname: Pyo
authors.forename: Joo Ah
authors.initials: JA
authors.lastname: Lee
authors.forename: Hoon Sup
authors.initials: HS
authors.lastname: Koo
authors.forename: Kyu Chan
authors.initials: KC
authors.lastname: Huh
mesh_terms: D000091162:AMP-Activated Protein Kinase Kinases; D000328:Adult; D003424:Crohn Disease / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology; D007416:Intestinal Perforation / Q000209:etiology; D007417:Intestinal Polyps / Q000473:pathology / Q000601:surgery; D008297:Male; D010580:Peutz-Jeghers Syndrome / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D017346:Protein Serine-Threonine Kinases / Q000235:genetics
chemical_list: D017346:Protein Serine-Threonine Kinases; C109790:STK11 protein, human; D000091162:AMP-Activated Protein Kinase Kinases