title: [The influence of physical-chemical characteristics of surface modified copper nanoparticles on E. coli cell population growth suppression and on electrostatic properties of their membranes].
abstract: The biological activity of copper nanoparticles, able to suppress growth of E. coli cells population under contact interactions, was explored. Three types of samples with oxide layers of various sizes, thickness and composition were used in experiments. It was found out, that an increase in electron density on the external membrane of E. coli correlated with copper nanoparticles suppression capability and with lower activation energy of electron transfer on bacteria. The analysis of experimental data helps to correct conditions for obtaining nanoparticles with certain properties of their surface oxide layers. The character of temperature dependence of electron density reveals the electron type of conductivity in contact area of E. coli and nanoparticles. These results help to find approach to understanding the nature of toxic influence of copper nanoparticles on E. coli cells under contact interaction.
authors.forename: L A
authors.initials: LA
authors.lastname: Volodina
authors.forename: A N
authors.initials: AN
authors.lastname: Zhigach
authors.forename: I O
authors.initials: IO
authors.lastname: Leĭpunskiĭ
authors.forename: E S
authors.initials: ES
authors.lastname: Zotova
authors.forename: N N
authors.initials: NN
authors.lastname: Glushchenko
mesh_terms: D002462:Cell Membrane / Q000378:metabolism* / Q000648:ultrastructure; D003300:Copper / Q000737:chemistry / Q000494:pharmacology*; D048168:Escherichia coli K12 / Q000254:growth & development* / Q000378:metabolism / Q000648:ultrastructure; D053768:Metal Nanoparticles; D010084:Oxidation-Reduction / Q000187:drug effects
chemical_list: D003300:Copper