title: Profile: Manhiça Health Research Centre (Manhiça HDSS).
abstract: The Manhiça Health Research Centre, established in 1996 in a rural area of southern Mozambique, currently follows around 92 000 individuals living in approximately 20 000 enumerated and geo-positioned households. Its main strength is the possibility of linking demographic data and clinical data to promote and conduct biomedical research in priority health areas. Socio-demographic data are updated twice a year and clinical data are collected on a daily basis. The data collected in Manhiça HDSS comprises household and individual characteristics, household socio-economic assets, vital data, migration, individual health history and cause of death, among others. Studies conducted in this HDSS contributed to guide the health authorities and decision-making bodies to define or adjust health policies such as the introduction of Mozambique's expanded programme of immunization with different vaccines (Haemophilus influenzae type b, Pneumococcus) or the development of the concept of Intermittent Preventive Treatment for Infants (IPTi) that led to the World Health Organization recommendation of this method as best practice for the control of malaria among infants. Manhiça's data can be accessed through a formal request to Diana Quelhas (diana.quelhas@manhica.net) accompanied by a proposal that will be analysed by the Manhiça HDSS internal scientific and ethics committees.
authors.affiliation: Manhiça Health Research Centre, Manhiça District, Mozambique, Barcelona Centre for International Health Research, Hospital Clínic/Universitat de Barcelona, Spain, National Directorate of Health, Ministry of Health, Maputo, Mozambique, National Institute of Health, Ministry of Health, Maputo Mozambique and Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
authors.forename: Charfudin
authors.initials: C
authors.lastname: Sacoor
authors.forename: Ariel
authors.initials: A
authors.lastname: Nhacolo
authors.forename: Delino
authors.initials: D
authors.lastname: Nhalungo
authors.forename: John J
authors.initials: JJ
authors.lastname: Aponte
authors.forename: Quique
authors.initials: Q
authors.lastname: Bassat
authors.forename: Orvalho
authors.initials: O
authors.lastname: Augusto
authors.forename: Inácio
authors.initials: I
authors.lastname: Mandomando
authors.forename: Jahit
authors.initials: J
authors.lastname: Sacarlal
authors.forename: Natu
authors.initials: N
authors.lastname: Lauchande
authors.forename: Betuel
authors.initials: B
authors.lastname: Sigaúque
authors.forename: Pedro
authors.initials: P
authors.lastname: Alonso
authors.forename: Eusébio
authors.initials: E
authors.lastname: Macete
authors.forename: Khátia
authors.initials: K
authors.lastname: Munguambe
authors.forename: Caterina
authors.initials: C
authors.lastname: Guinovart
authors.forename: Pedro
authors.initials: P
authors.lastname: Aide
authors.forename: Clara
authors.initials: C
authors.lastname: Menendez
authors.forename: Sozinho
authors.initials: S
authors.lastname: Acácio
authors.forename: Diana
authors.initials: D
authors.lastname: Quelhas
authors.forename: Esperança
authors.initials: E
authors.lastname: Sevene
authors.forename: Tacilta
authors.initials: T
authors.lastname: Nhampossa
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000517:prevention & control; D035843:Biomedical Research; D003625:Data Collection; D003967:Diarrhea / Q000453:epidemiology; D004403:Dysentery / Q000453:epidemiology; D004405:Dysentery, Bacillary / Q000453:epidemiology; D004641:Emigration and Immigration; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D017589:Immunization Programs; D008288:Malaria / Q000453:epidemiology / Q000517:prevention & control; D008297:Male; D009026:Mortality; D009073:Mozambique / Q000453:epidemiology; D018410:Pneumonia, Bacterial / Q000453:epidemiology / Q000517:prevention & control; D012424:Rural Population; D012480:Salmonella Infections / Q000453:epidemiology; D014376:Tuberculosis / Q000453:epidemiology / Q000628:therapy
keywords: HDSS; Rural Southern Mozambique; cause of death; fertility; health; households; migration; morbidity; mortality; population