title: Measurement of dentin hypersensitivity with the Jay Sensitivity Sensor Probe and the Yeaple probe to compare relief from dentin hypersensitivity by dentifrices.
abstract: OBJECTIVE
  To compare relief from dentin hypersensitivity (DH) after use of dentifrices formulated with potassium nitrate or fluoride. For the study, DH evaluations were conducted with the Jay Sensitivity Sensor Probe (Jay Probe), a novel tactile hypersensitivity instrument, in conjunction with three other DH methods, i.e. Yeaple probe (tactile), air blast, and the Visual Analog Scale (VAS).
  
  
  METHODS
  Adults (n = 100) who presented two teeth with DH and met study criteria were enrolled for this double-blind, randomized, parallel, controlled clinical trial conducted in an outpatient setting. DH evaluations at baseline were conducted by the tactile, air blast, and VAS methods. Subjects were randomly assigned a dentifrice formulated with 5% potassium nitrate and 1,000 ppm fluoride (as sodium monofluorophosphate) (Colgate Sensitive toothpaste; Test) or a commercially available fluoride dentifrice with 1,000 ppm fluoride as sodium monofluorophosphate (Colgate Cibaca toothpaste; Negative control). Subjects were recalled for DH evaluations after 4 and 8 weeks of product use.
  
  
  RESULTS
  85 subjects completed the entire study with evaluable results. Both treatments resulted in significant reductions in DH from baseline to all recall visits. In comparison to the Negative control, subjects in the Test group demonstrated significantly greater reductions for all DH evaluations at both 4 and 8 weeks (P < 0.05). Average tactile DH scores at week 8 for the Test and Negative control groups were 36.25 and 15.24 with the Yeaple probe and 35 and 12.43 with the Jay probe. Correspondingly, subjects in the Test group demonstrated significantly greater reductions in air blast and VAS responses for DH than those in the Negative control group (P < 0.05).
authors.affiliation: Global Health Research Group, H 8 Masjid Moth, Gk-2, New Delhi 110048, India. ashish@ghrg.org
authors.forename: Ashish
authors.initials: A
authors.lastname: Kakar
authors.forename: Kanupriya
authors.initials: K
authors.lastname: Kakar
mesh_terms: D000293:Adolescent; D000328:Adult; D000388:Air; D003802:Dentifrices / Q000627:therapeutic use*; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000175:diagnosis / Q000517:prevention & control*; D019719:Diagnostic Equipment; D004311:Double-Blind Method; D004867:Equipment Design; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008838:Microcomputers; D008875:Middle Aged; D009566:Nitrates / Q000627:therapeutic use; D010147:Pain Measurement; D010710:Phosphates / Q000627:therapeutic use; D010812:Physical Stimulation; D017680:Potassium Compounds / Q000627:therapeutic use; D014110:Touch; D014160:Transducers, Pressure; D055815:Young Adult
chemical_list: D003802:Dentifrices; D057133:Dentin Desensitizing Agents; D009566:Nitrates; D010710:Phosphates; D017680:Potassium Compounds; C012980:fluorophosphate; D005459:Fluorides; C023844:potassium nitrate