title: [Lifestyle-recommendations on weight loss in type 2 diabetes--useful, or not?].
abstract: Weight loss is recommended for overweight or obese patients with type 2 diabetes on the basis of short-term studies, but the long-term effects of weight loss on cardiovascular disease are unknown. The recently published Look AHEAD (Action for health in diabetes) study investigated the 10-year effect of an intensive lifestyle intervention designed to achieve weight loss on cardiovascular morbidity and mortality among overweight or obese adults with type 2 diabetes. In this commentary, we discuss the results and clinical implications of this study.
authors.affiliation: Academisch Medisch Centrum, afd. Inwendige Geneeskunde, Amsterdam.
authors.forename: Wanda M
authors.initials: WM
authors.lastname: Admiraal
authors.forename: Frits
authors.initials: F
authors.lastname: Holleman
authors.forename: Joost B L
authors.initials: JB
authors.lastname: Hoekstra
mesh_terms: D002318:Cardiovascular Diseases / Q000401:mortality / Q000517:prevention & control; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000628:therapy*; D015431:Weight Loss / Q000502:physiology*