title: Enteropathogenic Escherichia coli Outbreak and its Incubation Period: Is it Short or Long?
abstract: OBJECTIVE
  The aim of this study is to determine the incubation period of enteropathogenic Escherichia coli (EPEC), which creates several outbreaks in a year in South Korea.
  
  
  METHODS
  We reviewed all water and food-borne outbreaks data reported to the Korea Centers for Disease Control and Prevention (KCDC) from 2009 to 2010 and determined their characteristics. Through this process, we can presume the incubation period of EPEC among outbreaks in South Korea.
  
  
  RESULTS
  A total of 497 water and food-borne outbreaks were reported to KCDC and 66 (13.28%) are defined as E coli-origin outbreaks. EPEC was the most common subtype of E coli, being confirmed as a causative organism in 26 outbreaks. Overall attack rate was 15.85% (range 0.9-100). The subjects were eight outbreaks that have a clear history of single exposure and we can estimate the incubation time of EPEC as minimum 0.5 hours to maximum 34.0 hours with a mean 12.9 hours (range 4.5-24.0). The cases of those cannot completely rule out the chance of multiple exposure from same source or place have minimum 1.0 hour, to a maximum of 195.5 hours and a mean 30.5 (range 22.7-61.0) hours of incubation period.
  
  
  CONCLUSIONS
  This serial analysis suggests that EPEC has actually shorter mean incubation period as much as 12 hours. When this period is longer than 1 day or over, then the epidemiologic investigator should consider the chance of repeated or continuous exposure by making it clear whether there is any chance of any other exposure in common.
authors.affiliation: Division of Public Health Crisis Responses, Korea Centers for Disease Control and Prevention, Osong, Korea.
authors.forename: Dong-Woo
authors.initials: DW
authors.lastname: Lee
authors.forename: Jin
authors.initials: J
authors.lastname: Gwack
authors.forename: Seun-Ki
authors.initials: SK
authors.lastname: Youn
keywords: EPEC; enteropathogenic E coli; incubation period; outbreak; single exposure