title: Clinical Recovery despite Cortical Cerebral and Cerebellar Damage in Heat Stroke.
abstract: The prognosis of heat stroke has considerably improved with a mortality rate drop to 10% when therapeutic measurements including external cooling and aggressive rehydration are adopted. The role of imaging in predicting prognosis is uncertain. Some noted that development of cortical cerebellar atrophy is associated with development of a pancerebellar syndrome, while others suggested that evidence of cerebral cortical damage due to hypoxic-ischemic injury implies a poor prognosis. We observed a 17-year-old female who presented with lost of consciousness and seizure while jogging on a hot summer day followed by multi-organ failure. Brain MRI revealed a symmetric area of T2 hyperintensity and decreased diffusion in the cortical gyri of the frontal lobes. The patient made a complete recovery. MRI two years later showed disappearance of signal changes in the frontal cortex, but progressive atrophy of the cerebellum which was clinically silent. Our observation challenges the view of a close correlation between the imaging findings and prognosis in heat stroke.
authors.affiliation: Department of Radiology, University of Pisa; Pisa, Italy - s.decori@libero.it.
authors.forename: S
authors.initials: S
authors.lastname: De Cori
authors.forename: G
authors.initials: G
authors.lastname: Biancofiore
authors.forename: L
authors.initials: L
authors.lastname: Bindi
authors.forename: M
authors.initials: M
authors.lastname: Cosottini
authors.forename: I
authors.initials: I
authors.lastname: Pesaresi
authors.forename: L
authors.initials: L
authors.lastname: Murri
authors.forename: M
authors.initials: M
authors.lastname: Mascalchi