title: Neurological complications of tick borne encephalitis: the experience of 89 patients studied and literature review.
abstract: Tick borne encephalitis (TBE) is an acute febrile syndrome that can be complicated with neurological symptoms ranging from mild meningitis to severe encephalomyelitis. The causative agent is a virus belonging to the family of flaviviruses. We have collected a series of 89 patients and compared the clinical course with the main data of the literature of TBE. This review in addition describes the clinical manifestations associated with TBE infections, the main molecular-biological properties of these viruses, and the different factors that define the incidence and severity of disease who are frequently situated in the age group young/adult with a social harm and functional non-negligible. This review also contains diagnostic elements and neuropathological features typical of this infection and a brief summary of vaccination against TBE.
authors.affiliation: Department of Neurology, San Martino Hospital, Belluno, Italy, sandro.zambito@ulss.belluno.it.
authors.forename: Sandro
authors.initials: S
authors.lastname: Zambito Marsala
authors.forename: Michele
authors.initials: M
authors.lastname: Pistacchi
authors.forename: Manuela
authors.initials: M
authors.lastname: Gioulis
authors.forename: Rosanna
authors.initials: R
authors.lastname: Mel
authors.forename: Corrado
authors.initials: C
authors.lastname: Marchini
authors.forename: Ermenegildo
authors.initials: E
authors.lastname: Francavilla
mesh_terms: D004675:Encephalitis, Tick-Borne / Q000150:complications*; D006801:Humans; D009422:Nervous System Diseases / Q000821:virology*