title: An unusual case of diffuse large B-cell lymphoma involving the vulva evaluated by 18F-FDG PET/CT.
abstract: We describe an unusual case of diffuse large B-cell lymphoma involving the vulva detected and staged by F-FDG PET/CT. An 83-year-old female patient with history of endometrial carcinoma underwent F-FDG PET/CT for follow-up. PET/CT detected an area of increased F-FDG uptake corresponding to a vulvar nodule; moderate and diffuse F-FDG uptake in the bone marrow was also evident. Based on these PET/CT findings, the patient underwent biopsy of the vulvar nodule. Histology demonstrated the presence of a diffuse large B-cell lymphoma of the vulva. Bone marrow biopsy was positive for lymphoid infiltration.
authors.affiliation: From the *Department of Nuclear Medicine and PET/CT Centre, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland; and †Institute of Pathology, Locarno, Switzerland.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Treglia
authors.forename: Gaetano
authors.initials: G
authors.lastname: Paone
authors.forename: Ulrike
authors.initials: U
authors.lastname: Perriard
authors.forename: Luca
authors.initials: L
authors.lastname: Ceriani
authors.forename: Luca
authors.initials: L
authors.lastname: Giovanella
mesh_terms: D000369:Aged, 80 and over; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D016403:Lymphoma, Large B-Cell, Diffuse / Q000000981:diagnostic imaging*; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D014844:Vulva / Q000000981:diagnostic imaging* / Q000473:pathology
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18