title: A population approach to renal replacement therapy epidemiology: lessons from the EVEREST study.
abstract: The marked variation that exists in renal replacement therapy (RRT) epidemiology between countries and within countries requires careful systematic examination if the root causes are to be understood. While individual patient-level studies are undoubtedly important, there is a complementary role for more population-level, area-based studies--an aetiological approach. The EVEREST Study adopted such an approach, bringing RRT incidence rates, survival and modality mix together with macroeconomic factors, general population factors and renal service organizational factors for up to 46 countries. This review considers the background to EVEREST, its key results and then the main methodological lessons and their potential application to ongoing work.
authors.affiliation: Richard Bright Renal Unit, Southmead Hospital, Bristol, UK School of Clinical Sciences, University of Bristol, Bristol, UK.
authors.forename: Fergus J
authors.initials: FJ
authors.lastname: Caskey
authors.affiliation: ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Kitty J
authors.initials: KJ
authors.lastname: Jager
mesh_terms: D014943:Global Health; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology* / Q000628:therapy*; D009017:Morbidity / Q000639:trends; D017582:Renal Replacement Therapy / Q000706:statistics & numerical data*; D012107:Research Design
keywords: aetiology; epidemiology; macroeconomics; renal replacement therapy; renal service organization