title: Bilateral macrodystrophia lipomatosa with syndactyly: a case report and literature review.
abstract: Macrodystrophia lipomatosa is a rare, non-hereditary form of congenital local gigantism characterised by enlargement and hypertrophy of all mesenchymal tissue components with a disproportionate increase in adipose tissue. This form of macrodactyly has been reported in association with other anomalies including polydactyly, brachydactyly, syndactyly, and symphalangism. We describe a previously unreported case of bilateral upper extremity macrodystrophia lipomatosa with syndactyly in a 23-month-old boy. In this report, we emphasise the importance of establishing a diagnosis with imaging and review the described surgical approaches to treating this difficult condition.
authors.affiliation: Division of Plastic Surgery, Michael E. Debakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
authors.forename: Steven B
authors.initials: SB
authors.lastname: Albright
authors.forename: Erik M
authors.initials: EM
authors.lastname: Wolfswinkel
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Caceres
authors.forename: William M
authors.initials: WM
authors.lastname: Weathers
authors.forename: Larry H
authors.initials: LH
authors.lastname: Hollier
mesh_terms: D000015:Abnormalities, Multiple; D003937:Diagnosis, Differential; D005385:Fingers / Q000002:abnormalities* / Q000601:surgery; D005500:Follow-Up Studies; D005877:Gigantism / Q000151:congenital*; D006801:Humans; D008068:Lipomatosis / Q000151:congenital* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D019637:Orthopedic Procedures / Q000379:methods*; D013576:Syndactyly / Q000175:diagnosis*; D055815:Young Adult