title: Transient anterior subcapsular vacuolar change of the crystalline lens in patients after posterior chamber phakic intraocular lens implantation.
abstract: BACKGROUND
  We present two cases of transient vacuolar changes in the anterior subcapsular space of the crystalline lens in patients after posterior chamber phakic intraocular lens implantation.
  
  
  METHODS
  Implantable collamer lenses (ICL) were implanted in healthy myopic patients. Vacuolar changes developed just after the irrigating procedure through the narrow space between the ICL and the crystalline lens. Slit-lamp examinations and spectral domain optical coherence tomography showed bleb-like lesions in the anterior subcapsular space of one eye in each case, though the lesions gradually improved without visual deterioration. Consequently, the lesions turned into a few anterior subcapsular small faint opacities.
  
  
  CONCLUSIONS
  Direct irrigation of the narrow space confined by the ICL and the crystalline lens is at risk for the development of vacuolar changes in the crystalline lens. The observed spontaneous reversal indicates that surgeons should not rush to surgical intervention but rather opt for close follow over several weeks.
authors.forename: Jin Kwon
authors.initials: JK
authors.lastname: Chung
authors.forename: Jin Hee
authors.initials: JH
authors.lastname: Shin
authors.affiliation: Department of Ophthalmology, Soonchunhyang University Hospital, 59, Daesagwan-gil, Yongsan-gu, Seoul 140-743, Republic of Korea. wismile@schmc.ac.kr.
authors.forename: Sung Jin
authors.initials: SJ
authors.lastname: Lee
mesh_terms: D000328:Adult; D000869:Anterior Eye Segment / Q000473:pathology*; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000009:adverse effects*; D007908:Lens, Crystalline / Q000473:pathology*; D008297:Male; D009216:Myopia / Q000601:surgery*; D054120:Phakic Intraocular Lenses; D011183:Postoperative Complications; D007507:Therapeutic Irrigation / Q000009:adverse effects