title: Overview of the pancreatic toxicity and carcinogenesis session.
abstract: The theme of the Society of Toxicologic Pathology Annual Symposium 2013 was "Toxicologic Pathology of the Digestive Tract and Pancreas." The last session focused on pancreatic toxicity and carcinogenesis. This overview highlights the various presentations in this session, focusing on pancreatic toxicologic pathology, responses of the pancreas to xenobiotics, and current understanding on pancreatic carcinogenesis. The objective of this symposium overview and the subsequent articles from this session is to enable the audience to develop a better appreciation for the pancreas as a target organ in toxicological studies.
authors.affiliation: 1Experimental Pathology Laboratories, Inc., Research Triangle Park, North Carolina, USA.
authors.forename: Arun R
authors.initials: AR
authors.lastname: Pandiri
authors.forename: A Eric
authors.initials: AE
authors.lastname: Schultze
mesh_terms: D000818:Animals; D063646:Carcinogenesis / Q000473:pathology*; D004195:Disease Models, Animal; D006801:Humans; D010179:Pancreas / Q000187:drug effects / Q000473:pathology*; D010182:Pancreatic Diseases / Q000473:pathology*; D015262:Xenobiotics / Q000009:adverse effects
chemical_list: D015262:Xenobiotics
keywords: CCK agonist; cholecystokinin; exocrine pancreas; islet–acinar axis; pancreatic cancer.; pancreatitis