title: [Effects of gastric bypass on estimated cardiovascular risk in morbidly obese patients with metabolic syndrome].
abstract: BACKGROUND
  The major goal of surgical treatment in morbid obesity is to decrease morbidity and mortality associated with excess weight. In this sense, the main factors of death are cardiovascular disease and metabolic syndrome. The objective of this study is to evaluate the effects of gastric bypass on cardiovascular risk estimation in patients after bariatric surgery.
  
  
  METHODS
  We retrospectively evaluated pre and postoperative cardiovascular risk estimation of 402 morbidly obese patients who underwent laparoscopic gastric bypass. The major variable studied is the cardiovascular risk estimation that is calculated preoperatively and after 12 months. Cardiovascular risk estimation analysis has been performed with the REGICOR Equation. REGICOR formulation allows calculating a 10 year risk of cardiovascular events adapted to the Spanish population and is expressed in percentages.
  
  
  RESULTS
  We reported an overall 4.1±3.0 mean basal REGICOR score. One year after the operation, cardiovascular risk estimation significantly decreased to 2,2±1,6 (P<.001). In patients with metabolic syndrome according to ATP-III criteria, basal REGICOR score was 4.8±3.1 whereas in no metabolic syndrome patients 2.2±1.8. Evaluation 12 months after surgery, determined a significant reduction in both groups (metabolic syndrome and non metabolic syndrome) with a mean REGICOR score of 2.3±1.6 and 1.6±1.0 respectively.
  
  
  CONCLUSIONS
  The results of our study demonstrate favorable effects of gastric bypass on the cardiovascular risk factors included in the REGICOR equation.
authors.affiliation: Servicio de Cirugía Gastrointestinal, Unidad Funcional de la Obesidad, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic de Barcelona, Barcelona, España. Electronic address: rcodina@clinic.ub.es.
authors.forename: Ricard
authors.initials: R
authors.lastname: Corcelles
authors.affiliation: Servicio de Endocrinología, Unidad Funcional de la Obesidad, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic de Barcelona, Barcelona, España.
authors.forename: Josep
authors.initials: J
authors.lastname: Vidal
authors.affiliation: Servicio de Cirugía Gastrointestinal, Unidad Funcional de la Obesidad, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic de Barcelona, Barcelona, España.
authors.forename: Salvadora
authors.initials: S
authors.lastname: Delgado
authors.affiliation: Servicio de Cirugía Gastrointestinal, Unidad Funcional de la Obesidad, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic de Barcelona, Barcelona, España.
authors.forename: Ainitze
authors.initials: A
authors.lastname: Ibarzabal
authors.affiliation: Servicio de Cirugía Gastrointestinal, Unidad Funcional de la Obesidad, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic de Barcelona, Barcelona, España.
authors.forename: Raquel
authors.initials: R
authors.lastname: Bravo
authors.affiliation: Servicio de Cirugía Gastrointestinal, Unidad Funcional de la Obesidad, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic de Barcelona, Barcelona, España.
authors.forename: Dulce
authors.initials: D
authors.lastname: Momblan
authors.affiliation: Servicio de Cirugía Gastrointestinal, Unidad Funcional de la Obesidad, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic de Barcelona, Barcelona, España.
authors.forename: Juanjo
authors.initials: J
authors.lastname: Espert
authors.affiliation: Servicio de Cirugía Gastrointestinal, Unidad Funcional de la Obesidad, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic de Barcelona, Barcelona, España.
authors.forename: Xavi
authors.initials: X
authors.lastname: Morales
authors.affiliation: Servicio de Cirugía Gastrointestinal, Unidad Funcional de la Obesidad, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic de Barcelona, Barcelona, España.
authors.forename: Raúl
authors.initials: R
authors.lastname: Almenara
authors.affiliation: Servicio de Cirugía Gastrointestinal, Unidad Funcional de la Obesidad, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic de Barcelona, Barcelona, España.
authors.forename: Antonio M
authors.initials: AM
authors.lastname: Lacy
mesh_terms: D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D015390:Gastric Bypass; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications* / Q000601:surgery*; D012189:Retrospective Studies; D018570:Risk Assessment
keywords: Bypass gástrico laparoscópico; Cardiovascular risk; Ecuación Registre Gironí del Cor; Equation Registre Gironí del Cor; Laparoscopic gastric bypass; Metabolic syndrome; Riesgo cardiovascular; Síndrome metabólico