title: Two new phenylpropanoid glycosides from the roots of Aruncus sylvester.
abstract: Two new phenylpropanoid glycosides, 1,3,4-tri-O-(E)-caffeoyl-β-d-glucopyranoside (1) and 1,4-di-O-(E)-caffeoyl-β-d-glucopyranoside (2), along with four known phenylpropanoid glycosides (3-6), were isolated from the roots of Aruncus sylvester. The structures of 1 and 2 were elucidated using various spectroscopic methods. Compounds 1 and 2 displayed significant scavenging activity of 2,2-diphenyl-1-picrylhydrazyl free radicals with IC50 values of 110 and 258 μM (ascorbic acid: IC50 = 574 μM).
authors.affiliation: a Tianjin Key Laboratory for Modern Drug Delivery and High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University , Tianjin , 300072 , China.
authors.forename: Meng
authors.initials: M
authors.lastname: Que
authors.forename: Yan-Fang
authors.initials: YF
authors.lastname: Su
authors.forename: Shi-Lun
authors.initials: SL
authors.lastname: Yan
authors.forename: Ya-Hui
authors.initials: YH
authors.lastname: Zhou
authors.forename: Xiu-Mei
authors.initials: XM
authors.lastname: Gao
mesh_terms: D000975:Antioxidants / Q000737:chemistry; D001713:Biphenyl Compounds / Q000494:pharmacology; D002109:Caffeic Acids / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification*; D005609:Free Radicals / Q000737:chemistry; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010666:Phenylpropionates / Q000737:chemistry / Q000302:isolation & purification*; D010851:Picrates / Q000494:pharmacology; D027824:Rosaceae / Q000737:chemistry*
chemical_list: C587129:1,3,4-tri-O-(E)-caffeoyl-beta-D-glucopyranoside; C587128:1,4-di-O-(E)-caffeoyl-beta-D-glucopyranoside; D000975:Antioxidants; D001713:Biphenyl Compounds; D002109:Caffeic Acids; D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers; D005609:Free Radicals; D005960:Glucosides; D010666:Phenylpropionates; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl