title: [Case-control study on the risk factors of type 2 diabetes of Dong nationality in Western Hunan].
abstract: OBJECTIVE
  To explore the risk factors of type 2 diabetes mellitus (T2DM) of Dong nationality in Western Hunan, and to provide a scientific basis for the prevention and treatment of T2DM in the district.
  
  
  METHODS
  In the case-control study, the subjects were divided into a T2DM group, an impaired glucose regulation (IGR) group and a normal glucose tolerance (NGT) group through oral glucose tolerance test (OGTT). A questionnaire survey was conducted, and physical measurements and the detection of blood glucose, blood lipids and serum insulin were done.
  
  
  RESULTS
  Univariate analysis found significant difference in age, fasting insulin (FINS), HOMA insulin resistance index (HOMA-IRI), HOMA β-cell function index (HOMA-βC), trigalloyl glycerol (TG), high density lipoprotein cholesterol (HDL-C), systolic blood pressure, and diastolic blood pressure in the glucose metabolism among different groups (P<0.05). Body mass index (BMI), waist/hip ratio (WHR), family history of diabetes, number of physical activities per week, dinner taste, fat and protein-rich foods, fresh vegetables and fruits intake were associated with T2DM. Multifactor non-conditional ordinal logistic regression indicated that age was the risk factor of T2DM and IGR. Compared with the group whose age was≤50, the odds ratios of the groups of 50<age≤60, 60<age≤70 and age>>70 were 1.85, 2.83 and 2.64 respectively, P<0.05. The risk of suffering from diabetes of the overweighted or obese people was 2.13 times that of a normal BMI group, P<0.01. The other influencing factors included WHR (OR=2.06), family history of diabetes (OR=11.36), and fat and protein-rich foods (OR=1.90).
  
  
  CONCLUSIONS
  The main influencing factors of T2DM of Dong nationality in Western Hunan include age, BMI, WHR, family history of diabetes, fat and protein-rich foods. We must strengthen the health eduation of T2DM of Dong nationality in Western Hunan to reduce the risk of T2DM.
authors.affiliation: School of Public Health, Central South University, Changsha 410078;Department of Medical Laboratory, Huaihua Medical College, Huaihua Hunan 418000,China.
authors.forename: Liya
authors.initials: L
authors.lastname: Liu
authors.forename: Lizhang
authors.initials: L
authors.lastname: Chen
authors.forename: Jinxiong
authors.initials: J
authors.lastname: Dai
authors.forename: Jiaxiong
authors.initials: J
authors.lastname: Chen
authors.forename: Ying
authors.initials: Y
authors.lastname: Liang
authors.forename: Tingli
authors.initials: T
authors.lastname: Pei
authors.forename: Yongbin
authors.initials: Y
authors.lastname: Huang
mesh_terms: D001786:Blood Glucose; D015992:Body Mass Index; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000208:ethnology; D005006:Ethnicity; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin; D007333:Insulin Resistance; D050417:Insulin-Secreting Cells; D008055:Lipids; D009765:Obesity; D050177:Overweight; D012307:Risk Factors; D012959:Socioeconomic Factors
chemical_list: D001786:Blood Glucose; D007328:Insulin; D008055:Lipids