title: Reduced collagen internalization via down-regulation of MRC2 expression by UVA irradiation and its recovery by all-trans retinoic acid.
authors.affiliation: Bioscience Research Institute, Amorepacific Corporation R&D Center, Yongin-si, Gyeonggi-do 446-729, Republic of Korea.
authors.forename: Joong Hyun
authors.initials: JH
authors.lastname: Shim
authors.affiliation: Bioscience Research Institute, Amorepacific Corporation R&D Center, Yongin-si, Gyeonggi-do 446-729, Republic of Korea. Electronic address: biopang@amorepacific.com.
authors.forename: Dong Wook
authors.initials: DW
authors.lastname: Shin
authors.affiliation: College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
authors.forename: Min Soo
authors.initials: MS
authors.lastname: Noh
authors.affiliation: Bioscience Research Institute, Amorepacific Corporation R&D Center, Yongin-si, Gyeonggi-do 446-729, Republic of Korea. Electronic address: TRLee@amorepacific.com.
authors.forename: Tae Ryong
authors.initials: TR
authors.lastname: Lee
mesh_terms: D002469:Cell Separation; D002478:Cells, Cultured; D003094:Collagen / Q000378:metabolism*; D015536:Down-Regulation; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism*; D005434:Flow Cytometry; D006801:Humans; D037241:Mannose-Binding Lectins / Q000378:metabolism*; D008562:Membrane Glycoproteins / Q000378:metabolism*; D008863:Microspheres; D011956:Receptors, Cell Surface / Q000378:metabolism*; D012867:Skin / Q000187:drug effects / Q000528:radiation effects*; D015595:Skin Aging; D014212:Tretinoin / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: C404106:MRC2 protein, human; D037241:Mannose-Binding Lectins; D008562:Membrane Glycoproteins; D011956:Receptors, Cell Surface; D014212:Tretinoin; D003094:Collagen
keywords: ATRA; All-trans retinoic acid; Collagen; Fibroblasts; HDEs; MRC2; NHDFs; UVA; Ultraviolet A; all-trans retinoic acid; human dermal equivalents; mannose receptor C, type 2; normal human dermal fibroblasts; ultraviolet A