title: Myofibroblastoma: an unusual rapidly growing benign tumour in a male breast.
abstract: Myofibroblastoma is an unusual benign tumour of the breast predominantly seen in men in their sixth to seventh decade. The gross appearance is that of a well circumscribed nodule, characteristically small, seldom exceeding 3 cm. We present a case of an unusually large myofibroblastoma, which mimicked a malignant breast tumour. A 40 years old male, known case of tetralogy of Fallot, was operated in infancy in abroad, presented with a rapid enlargement of right breast over 5 - 6 weeks. Examination revealed a firm 10 cm hemispherical lump occupying the whole of the right breast with normal overlying skin. Since core biopsy was inconclusive, a subcutaneous mastectomy was performed to remove the tumour, which weighed 500 gms. Histopathology and immunocytochemistry revealed a mixed classical and collagenised type of myofibroblastoma. The patient is well with no evidence of recurrence.
authors.affiliation: Department of Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
authors.forename: Atif
authors.initials: A
authors.lastname: Rafique
authors.forename: Ambreen
authors.initials: A
authors.lastname: Arshad
mesh_terms: D000328:Adult; D018567:Breast Neoplasms, Male / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D006177:Gynecomastia / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D008297:Male; D008408:Mastectomy; D009379:Neoplasms, Muscle Tissue / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D016896:Treatment Outcome; D014463:Ultrasonography