title: CD8 and CD4 T cells in west nile virus immunity and pathogenesis.
abstract: CD4 and CD8 T lymphocytes are adaptive immune cells that play a key role in the immune response to pathogens. They have been extensively studied in a variety of model systems and the mechanisms by which they function are well described. However, the responses by these cell types vary widely from pathogen to pathogen. In this review, we will discuss the role of CD8 and CD4 T cells in the immune response to West Nile virus infection.
authors.affiliation: Department of Immunology, University of Washington, Seattle, WA 98109, USA. mbevan@uw.edu.
authors.forename: Jason
authors.initials: J
authors.lastname: Netland
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Bevan
mesh_terms: D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D006801:Humans; D014901:West Nile Fever / Q000276:immunology* / Q000473:pathology*; D014902:West Nile virus / Q000276:immunology* / Q000472:pathogenicity*