title: Biofilm formation and antibiotic resistance in Salmonella Typhimurium are affected by different ribonucleases.
abstract: Biofilm formation and antibiotic resistance are important determinants for bacterial pathogenicity. Ribonucleases control RNA degradation and there is increasing evidence that they have an important role in virulence mechanisms. In this report, we show that ribonucleases affect susceptibility against ribosome-targeting antibiotics and biofilm formation in Salmonella.
authors.affiliation: Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal.
authors.forename: Margarida
authors.initials: M
authors.lastname: Saramago
authors.forename: Susana
authors.initials: S
authors.lastname: Domingues
authors.forename: Sandra Cristina
authors.initials: SC
authors.lastname: Viegas
authors.forename: Cecília Maria
authors.initials: CM
authors.lastname: Arraiano
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects / Q000254:growth & development*; D024881:Drug Resistance, Bacterial; D012260:Ribonucleases / Q000378:metabolism*; D012486:Salmonella typhimurium / Q000187:drug effects / Q000201:enzymology* / Q000502:physiology*
chemical_list: D000900:Anti-Bacterial Agents; D012260:Ribonucleases