title: How will the growing threat of resistant hypertension impact the future treatment of high blood pressure?
abstract: Hypertension treatment and control efforts represent a major component of primary care with dedicated clinical guidelines and recommendations. However, high blood pressure (BP) control rates are complicated with the difficult to treat and resistant hypertensive patients. This category of patient, therefore, affects the development and implementation of the clinical guidelines. The recommendations of specific algorithms for resistant hypertension and difficult-to-treat patients with elevated BPs have been developed in consideration of new therapies and combination drug treatment. Hypertension treatment guidelines include and will continue to grade evidence from randomized clinical trials with detailed strategies on the management of these high-risk patients. Although resistant hypertension affects high BP control rates, the inclusion of refined pharmaceutical and device treatment strategies in evidence-based guidelines will be expected to have a significant impact on the clinical management of this high-risk patient population.
authors.affiliation: Department of Neurosciences, Medical University of South Carolina, 19 Hagood Ave, Suite 501,Charleston, SC 29425, USA +1 843 876 1141 lackland@musc.edu.
authors.forename: Daniel T
authors.initials: DT
authors.lastname: Lackland
mesh_terms: D000465:Algorithms; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure; D004351:Drug Resistance; D019317:Evidence-Based Medicine; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D017410:Practice Guidelines as Topic; D012306:Risk; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents