title: Fast, single-step, and surfactant-free oligonucleotide modification of gold nanoparticles using DNA with a positively charged tail.
abstract: Fast modification of large gold nanoparticles with DNA is achieved by using DNA with a polycationic tail. The conjugated DNA is available for specific hybridization, and therefore can be used for DNA-based assays or for constructing nanoparticle superstructures based on DNA hybridization.
authors.affiliation: Nanobiophysics Group, MIRA Institute of Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands. r.gill@utwente.nl.
authors.forename: Ron
authors.initials: R
authors.lastname: Gill
authors.forename: Kristian
authors.initials: K
authors.lastname: Göeken
authors.forename: Vinod
authors.initials: V
authors.lastname: Subramaniam
mesh_terms: D000327:Adsorption; D004247:DNA / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D007700:Kinetics; D053768:Metal Nanoparticles / Q000737:chemistry*; D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013438:Sulfhydryl Compounds / Q000737:chemistry; D013501:Surface-Active Agents / Q000737:chemistry
chemical_list: D009841:Oligonucleotides; D013438:Sulfhydryl Compounds; D013501:Surface-Active Agents; D006046:Gold; D004247:DNA