title: Role of surgery in pediatric ulcerative colitis.
abstract: Pediatric ulcerative colitis (UC) has a more extensive and progressive clinical course than adult UC. Therefore, more aggressive initial therapies and more frequent surgical treatments are needed. The therapeutic goal is to gain clinical and laboratory control of the disease with minimal adverse effects while permitting the patient to function as normally as possible. Approximately 5-10 % of patients with UC require acute surgical intervention because of fulminant colitis refractory to medical therapy. Mucosal proctocolectomy with ileal J-pouch anal anastomosis is currently recommended as a standard curative surgical procedure for UC in both children and adults worldwide. This review will focus on the current issues regarding the surgical indications for pediatric UC, the technical details of procedures and results of most recent published series to take the most appropriate next step to improve the surgical outcomes and patients' quality of life.
authors.affiliation: Division of Pediatric Surgery, Department of Surgery, Bambino Gesù Children's Hospital IRCCS, Palidoro, Rome, Italy, emanuela.ceriati@opbg.net.
authors.forename: Emanuela
authors.initials: E
authors.lastname: Ceriati
authors.forename: Francesco
authors.initials: F
authors.lastname: De Peppo
authors.forename: Massimo
authors.initials: M
authors.lastname: Rivosecchi
mesh_terms: D001003:Anal Canal / Q000601:surgery*; D000714:Anastomosis, Surgical / Q000379:methods; D002648:Child; D002675:Child, Preschool; D003093:Colitis, Ulcerative / Q000601:surgery*; D039021:Colonic Pouches; D006801:Humans; D007082:Ileum / Q000601:surgery*; D016737:Proctocolectomy, Restorative / Q000379:methods*; D011788:Quality of Life