title: Sesquiterpenyl indoles.
abstract: The natural product sesquiterpenyl indoles are structural hybrids from farnesyl pyrophosphate and tryptophan or its precursors, often with unusual and complex structural features, many of them with interesting biological activities. In this review the compounds of this class known until now are classified, a biosynthetic approach of each group is proposed and a review of the synthesis or synthetic approaches is communicated.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Salamanca, Plaza de los Caidos 1-5, 37008 Salamanca, Spain. ismarcos@usal.es.
authors.forename: Isidro S
authors.initials: IS
authors.lastname: Marcos
authors.forename: Rosalina F
authors.initials: RF
authors.lastname: Moro
authors.forename: Isabel
authors.initials: I
authors.lastname: Costales
authors.forename: Pilar
authors.initials: P
authors.lastname: Basabe
authors.forename: David
authors.initials: D
authors.lastname: Díez
mesh_terms: D001688:Biological Products / Q000737:chemistry / Q000378:metabolism; D007211:Indoles / Q000737:chemistry / Q000378:metabolism; D015394:Molecular Structure; D011106:Polyisoprenyl Phosphates / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000378:metabolism
chemical_list: D001688:Biological Products; D007211:Indoles; D011106:Polyisoprenyl Phosphates; D012717:Sesquiterpenes; C004808:farnesyl pyrophosphate