title: Early impairment in brain metabolism detected by MR spectroscopy antedates structural changes in mouse models of spinocerebellar ataxias.
authors.affiliation: Center for High-Field MR, Medical University of Vienna, Vienna, Austria.
authors.forename: Vladimír
authors.initials: V
authors.lastname: Mlynárik
authors.forename: Mary C
authors.initials: MC
authors.lastname: McKenna
mesh_terms: D000818:Animals; D000067696:Ataxin-1; D000067528:Ataxins; D002531:Cerebellum / Q000378:metabolism* / Q000473:pathology*; D006801:Humans; D008297:Male; D009419:Nerve Tissue Proteins / Q000235:genetics*; D009687:Nuclear Proteins / Q000235:genetics*; D020754:Spinocerebellar Ataxias / Q000378:metabolism* / Q000473:pathology*
chemical_list: C000593749:ATXN1 protein, human; D000067696:Ataxin-1; D000067528:Ataxins; C000593750:Atxn1 protein, mouse; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins