title: Update on preventive therapy (prophylaxis) for hereditary angioedema.
abstract: Both prophylactic and acute treatment of hereditary angioedema have been revolutionized in the past decade. Effective prophylactic treatment has long been provided by the group of attenuated androgens and antifibrinolytic agents, but their use has been attended by side effects. Plasma derived C1 inhibitor has been added to the group of agents effective in prophylaxis and a group of agents, discussed elsewhere in this volume, has been added to the armamentarium for acute therapy.
authors.affiliation: Department of Pediatrics, Duke University Medical Center, Erwin Road, Durham, NC 27710, USA. Electronic address: frank007@mc.duke.edu.
authors.forename: Michael M
authors.initials: MM
authors.lastname: Frank
mesh_terms: D015119:Aminocaproic Acid / Q000627:therapeutic use; D054179:Angioedemas, Hereditary / Q000517:prevention & control* / Q000628:therapy*; D002986:Clinical Trials as Topic; D003174:Complement C1 Inactivator Proteins / Q000627:therapeutic use; D006801:Humans; D011292:Premedication
chemical_list: D003174:Complement C1 Inactivator Proteins; D015119:Aminocaproic Acid
keywords: Androgens; Antifibrinolytics; C1 inhibitor; Hereditary angioedema; Prophylaxis