title: Incidence and trends of stroke and its subtypes in Changsha, China from 2005 to 2011.
abstract: During the 1990s no significant changes were found for the high incidence of ischemic stroke (IS) in Changsha, in contrast to the increase observed in Beijing and Shanghai. However, the epidemiological patterns of stroke may change with economic development. This study aimed to examine the characteristics of stroke incidence transition in Changsha from 2005 to 2011. In 2007 two communities with a registered population of about 100,000 were selected and data from stroke patients who presented between 2005 and 2007 were retrospectively collected from January to June 2008. From January to December 2007 a stroke surveillance network was established and stroke patients who presented between 2008 and 2011 were prospectively registered. From 2005 to 2011 the mean annual age-adjusted incidence of first-ever stroke was 168.5/100,000 (95% confidence interval [CI] 159.0-178.0/100,000), with 189.3/100,000 (95% CI 175.1-178.0/100,000) for men and 148.7/100,000 (95% CI 136.0-161.4/100,000) for women. The mean annual age-adjusted incidence of IS, intracranial hemorrhage and subarachnoid hemorrhage was 72.6/100,000 (95% CI 66.3-78.9/100,000), 85.1/100,000 (95% CI 78.3-91.9/100,000) and 9.4/100,000 (95% CI 7.1-11.7/100,000), respectively. During the study period, the age-adjusted incidence of stroke increased at an annual rate of 3.7% (p=0.001); at 4.2% for men (p=0.001) and 3.1% for women (p=0.026). The age-adjusted incidence of IS increased at an annual rate of 3.5% (p=0.003) but no significant changes were seen for hemorrhagic stroke. Characteristics of stroke incidence transition may reflect underlying changes in risk factors and there is an urgent need to identify these factors and launch appropriate public health campaigns.
authors.affiliation: Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China. Electronic address: sunyanxia820701@163.com.
authors.forename: Xin-gang
authors.initials: XG
authors.lastname: Sun
authors.affiliation: Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
authors.forename: Yan-li
authors.initials: YL
authors.lastname: Wang
authors.affiliation: Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Zhang
authors.affiliation: Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
authors.forename: Te
authors.initials: T
authors.lastname: Wang
authors.affiliation: Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China. Electronic address: liuyh610622@163.com.
authors.forename: Yun-hai
authors.initials: YH
authors.lastname: Liu
authors.affiliation: Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Jin
authors.affiliation: Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
authors.forename: Ling-juan
authors.initials: LJ
authors.lastname: Li
authors.affiliation: Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Feng
mesh_terms: D017677:Age Distribution; D000368:Aged; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D017678:Sex Distribution; D020521:Stroke / Q000145:classification / Q000453:epidemiology*
keywords: Changsha; Incidence; Intracranial hemorrhage; Ischemic stroke; Stroke; Subarachnoid hemorrhage