title: Par-4 prevents breast cancer recurrence.
abstract: Therapy resistance and disease recurrence are two of the most challenging aspects in breast cancer treatment. A recent article in Cancer Cell makes a significant contribution toward a better understanding of this therapeutic problem by establishing downregulation of the tumor suppressor Par-4 as the primary determinant of breast cancer recurrence. This viewpoint brings forth the importance of their findings and its implications on future research and therapy.
authors.forename: Nikhil
authors.initials: N
authors.lastname: Hebbar
authors.forename: Tripti
authors.initials: T
authors.lastname: Shrestha-Bhattarai
authors.forename: Vivek M
authors.initials: VM
authors.lastname: Rangnekar
mesh_terms: D000818:Animals; D051017:Apoptosis Regulatory Proteins / Q000502:physiology*; D001943:Breast Neoplasms / Q000209:etiology*; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000209:etiology*
chemical_list: D051017:Apoptosis Regulatory Proteins