title: Factors associated with receipt of adjuvant chemotherapy among married women with breast cancer.
abstract: BACKGROUND
  Adjuvant chemotherapies are recommended for most women after breast cancer surgery, and can greatly affect the patients' survival. We describe and evaluate possible factors influencing receipt of postoperative adjuvant chemotherapy among breast cancer patients in China.
  
  
  METHODS
  A total of 1,431 women diagnosed with breast cancer from 1997 to 2005 were enrolled. We reviewed medical records and abstracted information about these patients. Details on social-demographic factors and clinical-pathological characteristics of participants were collected and analyzed. To meet our objectives, the patient's age at diagnosis, comorbidities, menstrual status, rural/urban status, tumor size, lymph node status, distant metastasis, tumor stage and hormone receptor status were estimated.
  
  
  RESULTS
  Overall, 936 of these 1,431 patients (65.41%) received adjuvant chemotherapy. Receipt of chemotherapy was significantly associated with age at diagnosis, rural-urban disparities, and lymph node status of patients, though no significant difference was found between the age <50 and age 50 to 64 groups. Moderate association was also observed between hormone receptor status and receipt of adjuvant chemotherapy, though it was still not statistically significant.
  
  
  CONCLUSIONS
  Our study suggests that age at diagnosis, rural-urban disparities and lymph node status of breast cancer patients are independent predictors for receipt of adjuvant chemotherapy among married Chinese women. Further investigations are warranted, and related public health education needs to be expanded in China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Hua
authors.initials: H
authors.lastname: Gao
authors.forename: Yulan
authors.initials: Y
authors.lastname: Bu
authors.affiliation: Department of Nursing, Qilu Hospital and School of Nursing, Shandong University, West Wenhua Road, Ji'nan, Shandong 250012, P,R China. fxiuzhen@sdu.edu.cn.
authors.forename: Xiuzhen
authors.initials: X
authors.lastname: Fan
authors.forename: Jihui
authors.initials: J
authors.lastname: Jia
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy* / Q000473:pathology; D018275:Carcinoma, Lobular / Q000188:drug therapy* / Q000473:pathology; D017024:Chemotherapy, Adjuvant / Q000706:statistics & numerical data; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D017533:Marital Status; D008593:Menopause; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis