title: Current Approaches of Bone Morphogenetic Proteins in Dentistry.
abstract: Bone morphogenic proteins (BMPs) are a group of osteoinductive proteins obtained from nonmineralized bone matrix; they are capable of stimulating the differentiation of pluripotent mesenchymal cells to osteoprogenitor cells. They have become a likely treatment option, given their action on regeneration and remodeling of bone lesions and increasing the bone response around alloplastic materials. It may be feasible in the near future for BMPs to replace autologous and allogenic bone grafts. The application of specific growth factors for osteoinduction without using a bone graft constitutes a real impact on bone regeneration. The use of BMP is not only focused on osteogenic regeneration: There are a variety of studies investigating other properties, such as periodontal or dental regeneration from the conservative viewpoint. In this review, we will highlight the role of the BMP in bone, periodontal and dental regeneration.
authors.affiliation: 1  School of Dentistry, University of Seville, Seville, Spain.
authors.forename: Rosa-María
authors.initials: RM
authors.lastname: Díaz-Sánchez
authors.affiliation: 1  School of Dentistry, University of Seville, Seville, Spain.
authors.forename: Rosa-María
authors.initials: RM
authors.lastname: Yáñez-Vico
authors.affiliation: 1  School of Dentistry, University of Seville, Seville, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Fernández-Olavarría
authors.affiliation: 1  School of Dentistry, University of Seville, Seville, Spain.
authors.forename: Regina
authors.initials: R
authors.lastname: Mosquera-Pérez
authors.affiliation: 1  School of Dentistry, University of Seville, Seville, Spain.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Iglesias-Linares
authors.affiliation: 2  Department of Stomatology, University of Seville, Seville, Spain.
authors.forename: Daniel
authors.initials: D
authors.lastname: Torres-Lagares
mesh_terms: D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D001861:Bone Regeneration; D002454:Cell Differentiation; D003813:Dentistry; D010012:Osteogenesis; D016212:Transforming Growth Factor beta
chemical_list: D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D016212:Transforming Growth Factor beta
keywords: bone morphogenetic proteins; bone regeneration; dental regeneration; periodontal regeneration