title: pH-Triggered Au-fluorescent mesoporous silica nanoparticles for 19F MR/fluorescent multimodal cancer cellular imaging.
abstract: Novel pH-triggered nanoprobe were fabricated for (19)F MRI and fluorescence imaging (MRI-FI) of cancer cells. The biocompatibility, durability, high internalizing efficiency and pore architecture justify the Au-fluorescent mesoporous silica nanoparticles as ideal, highly sensitive and highly specific vectors for (19)F MRI and FI of cancer cells.
authors.affiliation: Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory for Magnetic Resonance and Atomic and Molecular Physics, Wuhan Center for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan 430071, China. xinzhou@wipm.ac.cn.
authors.forename: Shizhen
authors.initials: S
authors.lastname: Chen
authors.forename: Yuqi
authors.initials: Y
authors.lastname: Yang
authors.forename: Haidong
authors.initials: H
authors.lastname: Li
authors.forename: Xin
authors.initials: X
authors.lastname: Zhou
authors.forename: Maili
authors.initials: M
authors.lastname: Liu
mesh_terms: D045744:Cell Line, Tumor; D003287:Contrast Media / Q000737:chemistry / Q000378:metabolism; D005461:Fluorine / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008279:Magnetic Resonance Imaging; D008856:Microscopy, Fluorescence; D053758:Nanoparticles / Q000737:chemistry* / Q000378:metabolism; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism; D016062:Porosity; D011859:Radiography; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D003287:Contrast Media; D005461:Fluorine; D006046:Gold; D012822:Silicon Dioxide