title: Ulcerative tracheobronchitis due to Aspergillus.
abstract: Aspergillus ulcerative tracheobronchitis is a life-threatening form of invasive aspergillosis and is seldom seen in patients without underlying an immunocompromised state. Bronchoscopists must be familiar with this entity and consider Aspergillus ulcerative tracheobronchitis whenever mucosal erosions are seen, especially when unconventional risk factors such as intensive care unit admission and short-term glucocorticoid therapy are present. We present a case of invasive Aspergillus causing widespread ulcerative tracheobronchitis in a 39-year-old man with an asthma exacerbation requiring intensive care unit admission.
authors.affiliation: Department of Respiratory Medicine, University of British Columbia, Vancouver, BC, Canada.
authors.forename: Giulio S
authors.initials: GS
authors.lastname: Dominelli
authors.forename: Tawimas
authors.initials: T
authors.lastname: Shaipanich
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D001249:Asthma / Q000503:physiopathology / Q000628:therapy; D001706:Biopsy; D001991:Bronchitis / Q000382:microbiology* / Q000473:pathology; D001999:Bronchoscopy; D003422:Critical Care / Q000379:methods; D006801:Humans; D033162:Incidental Findings; D008297:Male; D011743:Pyrimidines / Q000627:therapeutic use; D012121:Respiration, Artificial / Q000379:methods; D020545:Respiratory Mucosa / Q000382:microbiology / Q000473:pathology; D014136:Tracheitis / Q000382:microbiology* / Q000473:pathology; D014139:Tracheostomy / Q000379:methods; D017211:Treatment Failure; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use; D014456:Ulcer / Q000382:microbiology* / Q000473:pathology; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole