title: The intake effects of Cyssus sicyoides drink on body mass, glycemia and femur parameters in male rats.
abstract: BACKGROUND
  The Cissus sicyoides, popularly called insulin plant, the drink is widely used in folk medicine to control glycemia. However, there are not enough datas about the effect of Cissus sicyoides on bone physiology. Thus, the goal was evaluate the glycemia and femur parameters in male rats.
  
  
  METHODS
  Wistar male rats with 12 weeks were divided control group (C) and treated with 5% of Cissus sicyoides (CS). After 42 days of treatment the groups were sacrificed and the body mass (g), glycemia, body organs and femur parameters were assessed.
  
  
  RESULTS
  In the last week the CS group showed significantly lower body mass and lower glycemia. After 42 days the CS showed heart and liver mass were significantly lower. In regard to bone paramaters, the mass and BMD of femur were significantly lower in CS group.
  
  
  CONCLUSIONS
  Despite the Cissus sicyoides drink decrease the glycemia, nevertheless it intake does not seem unfavorable for bone parameters.
authors.affiliation: Department of Nutrition and Dietetics. Laboratory of Experimental Nutrition (LabNE). Nutrition College. Fluminense Federal University (UFF) Niterói. Brazil.
authors.forename: Paula Cristina
authors.initials: PC
authors.lastname: Alves da Silva
authors.forename: Adriana
authors.initials: A
authors.lastname: da Silva Leal
authors.forename: André Manoel
authors.initials: AM
authors.lastname: Correia dos Santos
authors.forename: Carlos Alberto
authors.initials: CA
authors.lastname: Soares da Costa
authors.forename: Gilson
authors.initials: G
authors.lastname: Teles Boaventura
authors.forename: Armando Ubirajara
authors.initials: AU
authors.lastname: Oliveira Sabaa Srur
mesh_terms: D000818:Animals; D001628:Beverages; D001786:Blood Glucose / Q000187:drug effects*; D015992:Body Mass Index; D015519:Bone Density / Q000187:drug effects*; D032422:Cissus; D005269:Femur / Q000187:drug effects* / Q000502:physiology*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D001786:Blood Glucose; D010936:Plant Extracts