title: Retrospective derivation and validation of a search algorithm to identify emergent endotracheal intubations in the intensive care unit.
abstract: BACKGROUND
  The development and validation of automated electronic medical record (EMR) search strategies are important in identifying emergent endotracheal intubations in the intensive care unit (ICU).
  
  
  OBJECTIVE
  To develop and validate an automated search algorithm (strategy) for emergent endotracheal intubation in the critically ill patient.
  
  
  METHODS
  The EMR search algorithm was created through sequential steps with keywords applied to an institutional EMR database. The search strategy was derived retrospectively through a secondary analysis of a 450-patient subset from the 2,684 patients admitted to either a medical or surgical ICU from January 1, 2010, through December 31, 2011. This search algorithm was validated against an additional 450 randomly selected patients. Sensitivity, specificity, and negative and positive predictive values of the automated search algorithm were compared with a manual medical record review (the reference standard) for data extraction of emergent endotracheal intubations.
  
  
  RESULTS
  In the derivation subset, the automated electronic note search strategy achieved a sensitivity of 74% (95% CI, 69%-79%) and a specificity of 98% (95% CI, 92%-100%). With refinements in the search algorithm, sensitivity increased to 95% (95% CI, 91%-97%) and specificity decreased to 96% (95% CI, 92%-98%) in this subset. After validation of the algorithm through a separate patient subset, the final reported sensitivity and specificity were 95% (95% CI, 86%-99%) and 100% (95% CI, 98%-100%).
  
  
  CONCLUSIONS
  Use of electronic search algorithms allows for correct extraction of emergent endotracheal intubations in the ICU, with high degrees of sensitivity and specificity. Such search algorithms are a reliable alternative to manual chart review for identification of emergent endotracheal intubations.
authors.forename: N J
authors.initials: NJ
authors.lastname: Smischney
authors.forename: V M
authors.initials: VM
authors.lastname: Velagapudi
authors.forename: J A
authors.initials: JA
authors.lastname: Onigkeit
authors.forename: B W
authors.initials: BW
authors.lastname: Pickering
authors.forename: V
authors.initials: V
authors.lastname: Herasevich
authors.forename: R
authors.initials: R
authors.lastname: Kashyap
mesh_terms: D000465:Algorithms; D057225:Data Mining; D057286:Electronic Health Records; D006801:Humans; D007362:Intensive Care Units; D007442:Intubation, Intratracheal; D015203:Reproducibility of Results; D012121:Respiration, Artificial; D012189:Retrospective Studies; D018401:Sample Size
keywords: Electronic medical record; emergent; endotracheal intubation; intensive care unit; search algorithm