title: Recurrent bone fractures due to tenofovir-induced renal phosphate wasting.
abstract: A 42-y-old HIV-infected man suffered from several stress fractures due to tenofovir-induced proximal tubular injury. Laboratory examination revealed hypophosphatemia due to renal phosphate wasting. Therefore, more attention has to be paid to the monitoring of serum phosphate and alkaline phosphatase levels, since tenofovir-related nephrotoxicity increases the risk of osteomalacia.
authors.affiliation: From the Division of Nephrology, Kantonsspital Baselland , Liestal.
authors.forename: Katrin F
authors.initials: KF
authors.lastname: Koenig
authors.forename: Stefan
authors.initials: S
authors.lastname: Kalbermatter
authors.forename: Thomas
authors.initials: T
authors.lastname: Menter
authors.forename: Peter
authors.initials: P
authors.lastname: Graber
authors.forename: Denes
authors.initials: D
authors.lastname: Kiss
mesh_terms: D000225:Adenine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects* / Q000627:therapeutic use; D015775:Fractures, Stress / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced*; D008297:Male; D063065:Organophosphonates / Q000009:adverse effects* / Q000627:therapeutic use; D010710:Phosphates / Q000008:administration & dosage / Q000097:blood*; D011859:Radiography; D000068698:Tenofovir; D051598:Whole Body Imaging
chemical_list: D019380:Anti-HIV Agents; D063065:Organophosphonates; D010710:Phosphates; D000068698:Tenofovir; D000225:Adenine