title: Pd-catalyzed enantioselective C-H iodination: asymmetric synthesis of chiral diarylmethylamines.
abstract: An enantioselective C-H iodination reaction using a mono-N-benzoyl-protected amino acid has been developed for the synthesis of chiral diarylmethylamines. The reaction uses iodine as the sole oxidant and proceeds at ambient temperature and under air.
authors.affiliation: Department of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
authors.forename: Ling
authors.initials: L
authors.lastname: Chu
authors.forename: Xiao-Chen
authors.initials: XC
authors.lastname: Wang
authors.forename: Curtis E
authors.initials: CE
authors.lastname: Moore
authors.forename: Arnold L
authors.initials: AL
authors.lastname: Rheingold
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D008744:Methylamines / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D008744:Methylamines; D009942:Organometallic Compounds; D010165:Palladium