title: In vitro and in vivo imaging application of a 1,8-naphthalimide-derived Zn(2+) fluorescent sensor with nuclear envelope penetrability.
abstract: A newly developed fluorescent sensor, , shows a specific turn-on response to Zn(2+) and can be excited by visible light. The in situ nuclear Zn(2+) imaging in HeLa and HepG2 cells reveals the nuclear envelope penetrability of the sensor. The specific sensor location in a zebrafish larva was also demonstrated.
authors.affiliation: State Key Laboratory of Coordination Chemistry, Coordination Chemistry Institute, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China. heweij69@nju.edu.cn zguo@nju.edu.cn.
authors.forename: Changli
authors.initials: C
authors.lastname: Zhang
authors.forename: Zhipeng
authors.initials: Z
authors.lastname: Liu
authors.forename: Yunling
authors.initials: Y
authors.lastname: Li
authors.forename: Weijiang
authors.initials: W
authors.lastname: He
authors.forename: Xiang
authors.initials: X
authors.lastname: Gao
authors.forename: Zijian
authors.initials: Z
authors.lastname: Guo
mesh_terms: D000480:Alkynes / Q000737:chemistry; D000818:Animals; D000873:Anthracenes / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D056945:Hep G2 Cells; D006801:Humans; D007814:Larva / Q000378:metabolism; D008027:Light; D018613:Microscopy, Confocal; D009685:Nuclear Envelope / Q000737:chemistry / Q000378:metabolism*; D015027:Zebrafish / Q000254:growth & development; D015032:Zinc / Q000737:chemistry*
chemical_list: D000480:Alkynes; D000873:Anthracenes; D005456:Fluorescent Dyes; C545666:9,10-bis(phenylethynyl)anthracene; D015032:Zinc