title: Brain hypoperfusion on Tc-99m-ethylene dicysteine diethyl ester single-photon emission computed tomography in Hashimoto's encephalopathy.
abstract: We present a 17-year-old female, previously diagnosed of autoimmune hyperthyroidism who had an acute neurological episode and presented high antithyroid antibodies titers, cerebral spinal fluid and electroencephalogram changes. Tc-99m ethylene dicysteine diethyl ester brain single-photon emission computed tomography (SPECT) showed global and patchy hypoperfusion. With glucocorticoid therapy, clinical symptoms disappeared; there was a decrease in antithyroid antibody levels and repeat brain SPECT revealed improvement of perfusion.
authors.affiliation: Department of Nuclear Medicine, University Hospital "Infanta Cristina", Badajoz, Spain.
authors.forename: María Luz Domínguez
authors.initials: ML
authors.lastname: Grande
authors.forename: Ana
authors.initials: A
authors.lastname: Constantino
authors.forename: Juan Ignacio
authors.initials: JI
authors.lastname: Rayo
authors.forename: Justo
authors.initials: J
authors.lastname: Serrano
authors.forename: Jose Rafael
authors.initials: JR
authors.lastname: Infante
authors.forename: Lucia
authors.initials: L
authors.lastname: Garcia
authors.forename: Carmen
authors.initials: C
authors.lastname: Duran
keywords: Antithyroid antibodies; Hashimoto's encephalopathy; brain single-photon emission computed tomography; hypoperfusion