title: Thirty-day outcome of carotid artery stenting in Chinese patients: a single-center experience.
abstract: BACKGROUND
  Carotid artery stenting (CAS) as a competing treatment modality has had to adhere to limits to gain widespread acceptance in some studies. This study analyzed the clinical data of 1700 consecutive patients after CAS to retrospectively evaluate the 30-day outcome of CAS for internal carotid artery stenosis in a Chinese population.
  
  
  METHODS
  Medical records of 1700 patients who underwent CAS at Xuanwu Hospital affiliated to Capital Medical University between January 2001 and August 2012 were reviewed. Postoperative 30-day complication rates were analyzed and compared with those of other studies. Univariate and multivariate Logistic regression analyses were used to identify factors associated with perioperation myocardial infarction (MI), stroke, and death.
  
  
  RESULTS
  The overall 30-day rate of MI, stroke, and death after CAS was 2.53%. In univariate analysis, patients who were symptomatic, had a neurological deficit (modified Rankin score (mRS) ≥3; P = 0.001), and who were not taking statins experienced a significantly increased rate of MI, stroke, and death (P = 0.017). In multivariate Logistic regression analysis, the presence of symptoms (odds ratio (OR) = 2.485; 95% confidence interval (CI) = 1.267-4.876; P = 0.008) and a neurological deficit (mRS ≥3) (OR = 3.025; 95% CI = 1.353-6.763; P = 0.007) were independent risk factors for perioperative MI, stroke, and death.
  
  
  CONCLUSIONS
  According to this single-center experience, CAS may effectively prevent and treat carotid artery stenosis that would otherwise lead to stroke. Being symptomatic and having a neurological deficit (mRS ≥3) increased the risk of perioperative MI, stroke, and death.
authors.affiliation: Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
authors.forename: Li-qun
authors.initials: LQ
authors.lastname: Jiao
authors.forename: Gang
authors.initials: G
authors.lastname: Song
authors.forename: Shen-mao
authors.initials: SM
authors.lastname: Li
authors.forename: Zhong-rong
authors.initials: ZR
authors.lastname: Miao
authors.forename: Feng-shui
authors.initials: FS
authors.lastname: Zhu
authors.forename: Xun-ming
authors.initials: XM
authors.lastname: Ji
authors.forename: Guo-yang
authors.initials: GY
authors.lastname: Yin
authors.forename: Yan-fei
authors.initials: YF
authors.lastname: Chen
authors.forename: Ya-bing
authors.initials: YB
authors.lastname: Wang
authors.forename: Yan
authors.initials: Y
authors.lastname: Ma
authors.forename: Feng
authors.initials: F
authors.lastname: Ling
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016893:Carotid Stenosis / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction; D015607:Stents; D020521:Stroke / Q000601:surgery*; D016896:Treatment Outcome