title: Oncogenic brain metazoan parasite infection.
abstract: Multiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis, and a WHO grade IV neuroepithelial tumor with exclusively neuronal differentiation by immunohistochemical stains (immunopositive for synaptophysin, neurofilament protein, and Neu-N and not for GFAP, vimentin, or S100). The colocalization and temporal relationship of these two entities suggest a causal relationship.
authors.affiliation: Department of Surgery, Division of Neurological Surgery, School of Medicine, University of Missouri, Columbia, MO, USA.
authors.forename: Angela N
authors.initials: AN
authors.lastname: Spurgeon
authors.forename: Marshall C
authors.initials: MC
authors.lastname: Cress
authors.forename: Oroszi
authors.initials: O
authors.lastname: Gabor
authors.forename: Qing-Qing
authors.initials: QQ
authors.lastname: Ding
authors.forename: Tomoko
authors.initials: T
authors.lastname: Tanaka
authors.forename: Douglas C
authors.initials: DC
authors.lastname: Miller