title: Open-Phylo: a customizable crowd-computing platform for multiple sequence alignment.
abstract: Citizen science games such as Galaxy Zoo, Foldit, and Phylo aim to harness the intelligence and processing power generated by crowds of online gamers to solve scientific problems. However, the selection of the data to be analyzed through these games is under the exclusive control of the game designers, and so are the results produced by gamers. Here, we introduce Open-Phylo, a freely accessible crowd-computing platform that enables any scientist to enter our system and use crowds of gamers to assist computer programs in solving one of the most fundamental problems in genomics: the multiple sequence alignment problem.
authors.forename: Daniel
authors.initials: D
authors.lastname: Kwak
authors.forename: Alfred
authors.initials: A
authors.lastname: Kam
authors.forename: David
authors.initials: D
authors.lastname: Becerra
authors.forename: Qikuan
authors.initials: Q
authors.lastname: Zhou
authors.forename: Adam
authors.initials: A
authors.lastname: Hops
authors.forename: Eleyine
authors.initials: E
authors.lastname: Zarour
authors.forename: Arthur
authors.initials: A
authors.lastname: Kam
authors.forename: Luis
authors.initials: L
authors.lastname: Sarmenta
authors.forename: Mathieu
authors.initials: M
authors.lastname: Blanchette
authors.forename: Jérôme
authors.initials: J
authors.lastname: Waldispühl
mesh_terms: D000465:Algorithms; D023281:Genomics / Q000379:methods*; D008962:Models, Theoretical; D016415:Sequence Alignment / Q000379:methods*; D017421:Sequence Analysis / Q000379:methods*; D018910:Video Games