title: Changing the intraoperative nodal status of a breast cancer patient using freehand SPECT for sentinel lymph node biopsy.
abstract: Radio-guided sentinel lymph node biopsy in early-stage breast cancer is standard of care. Freehand SPECT is a system for intraoperative visualization of radioactivity in the body. It generates a 3-dimensional image of the radioactivity distribution complementing the acoustic information of the gamma probe by providing depth and radioactive uptake information. In the reported case, freehand SPECT was used in a breast cancer patient as a control method after conventional sentinel lymph node biopsy. Freehand SPECT identified an additional lymph node, changing the original stage from pN1(mic) (micrometastasis) to pN1a (nodal positive), resulting in an axillary lymph node dissection.
authors.affiliation: From the *Department of Nuclear Medicine, Technische Universität München, Munich; †Department of Nuclear Medicine, University of Würzburg, Würzburg; and ‡Department of Obstetrics and Gynecology, Technische Universität München, Munich, Germany.
authors.forename: Christina
authors.initials: C
authors.lastname: Bluemel
authors.forename: Andreas
authors.initials: A
authors.lastname: Schnelzer
authors.forename: Alexandra
authors.initials: A
authors.lastname: Ehlerding
authors.forename: Klemens
authors.initials: K
authors.lastname: Scheidhauer
authors.forename: Marion
authors.initials: M
authors.lastname: Kiechle
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D021701:Sentinel Lymph Node Biopsy; D015899:Tomography, Emission-Computed, Single-Photon