title: A colorimetric and fluorometric BODIPY probe for rapid, selective detection of H2S and its application in live cell imaging.
abstract: A BODIPY-azide based colorimetric and fluorescence turn-ON probe for rapid, selective and sensitive detection of H2S is reported. The probe displayed a fast response time (10 min in HEPES and 30 s in serum albumin), 28-fold fluorescence enhancement and low detection limit up to 259 nM. The application of the probe to the estimation of H2S in live cells was demonstrated.
authors.affiliation: Department of Chemistry, Mendeleev Block. and Indian Institute of Science Education and Research, Pune, India. ptalukdar@iiserpune.ac.in.
authors.forename: Tanmoy
authors.initials: T
authors.lastname: Saha
authors.forename: Dnyaneshwar
authors.initials: D
authors.lastname: Kand
authors.forename: Pinaki
authors.initials: P
authors.lastname: Talukdar
mesh_terms: D001896:Boron Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D002470:Cell Survival; D003124:Colorimetry; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D006862:Hydrogen Sulfide / Q000032:analysis*; D015394:Molecular Structure; D013050:Spectrometry, Fluorescence
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D005456:Fluorescent Dyes; D006862:Hydrogen Sulfide