title: Pd(II)-catalyzed one-pot, three-step route for the synthesis of unsymmetrical acridines.
abstract: Unsymmetric acridines are synthesized via a one-pot amination/cyclization/aromatization reaction for the first time. With Pd(OAc)2-X-Phos as the catalyst, a series of unsymmetric acridines are obtained in moderate to excellent yields (up to 99% yield). Meanwhile, the diphenylamine intermediate could be isolated, which is evidence of the domino process.
authors.affiliation: School of Chemistry and Chemical Engineering, Henan Normal University , Xinxiang 453007, Henan, China, and School of Chemistry and Chemical Engineering, Henan Institute of Science and Technology , Xinxiang 453003, China.
authors.forename: Hai-Ming
authors.initials: HM
authors.lastname: Guo
authors.forename: Run-Ze
authors.initials: RZ
authors.lastname: Mao
authors.forename: Qiao-Tian
authors.initials: QT
authors.lastname: Wang
authors.forename: Hong-Ying
authors.initials: HY
authors.lastname: Niu
authors.forename: Ming-Sheng
authors.initials: MS
authors.lastname: Xie
authors.forename: Gui-Rong
authors.initials: GR
authors.lastname: Qu
mesh_terms: D000166:Acridines / Q000138:chemical synthesis* / Q000737:chemistry; D000586:Amination; D002384:Catalysis; D003500:Cyclization; D004159:Diphenylamine / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D000166:Acridines; D010165:Palladium; D004159:Diphenylamine