title: No relevant association between coronary artery ectasia and mean platelet volume, gamma-glutamyltransferase and uric acid levels.
abstract: OBJECTIVE
  In this study, we aimed to investigate whether there is an association between mean platelet volume (MPV), gamma-glutamyltransferase (GGT) and uric acid and coronary artery ectasia (CAE) in a large patient population.
  
  
  METHODS
  A total of 406 patients (245 male, 161 female; mean age: 55±9 years) were selected retrospectively as the study population from among 3265 individuals who underwent coronary angiography between August 2011 and December 2012. Information regarding blood tests of the patients obtained during hospitalization was extracted from the institute electronic database.
  
  
  RESULTS
  MPV, GGT and uric acid levels were significantly higher in subjects with stenotic coronary artery disease (CAD) and in subjects with both CAD and CAE compared with subjects with isolated CAE and subjects with normal coronary arteries (NCA). There were no significant differences between the isolated CAE and NCA groups in terms of MPV (8.6±1.2 fL vs. 8.6±1.1, respectively, p=0.993), serum GGT (33±15 U/L vs. 30±15 U/L, respectively, p=0.723) and uric acid levels (5.4±1.6 mg/dl vs. 5.2±1.7 mg/dl, respectively, p=0.845).
  
  
  CONCLUSIONS
  Unlike previous studies, our study failed to demonstrate any association between CAE and MPV, uric acid and GGT levels.
authors.affiliation: Department of Cardiology, Kayseri Training and Research Hospital, Kayseri, Turkey. drsarli@yahoo.com.
authors.forename: Bahadır
authors.initials: B
authors.lastname: Sarlı
authors.forename: Ahmet Oğuz
authors.initials: AO
authors.lastname: Baktır
authors.forename: Hayrettin
authors.initials: H
authors.lastname: Sağlam
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Arınç
authors.forename: Serkan
authors.initials: S
authors.lastname: Kurtul
authors.forename: Zakir
authors.initials: Z
authors.lastname: Karadağ
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Katlandur
authors.forename: Mahmut
authors.initials: M
authors.lastname: Akpek
authors.forename: Mehmet Güngör
authors.initials: MG
authors.lastname: Kaya
mesh_terms: D003324:Coronary Artery Disease / Q000097:blood* / Q000201:enzymology / Q000473:pathology; D004108:Dilatation, Pathologic / Q000097:blood / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D012189:Retrospective Studies; D014527:Uric Acid / Q000097:blood*; D005723:gamma-Glutamyltransferase / Q000097:blood*
chemical_list: D014527:Uric Acid; D005723:gamma-Glutamyltransferase