title: Preparation and application of surface molecularly imprinted silica gel for selective extraction of melamine from milk samples.
abstract: Highly selective molecularly imprinted layer-coated silica gel (MIP@SiO2) for melamine (MEL) was prepared by the surface molecular imprinting technique on the supporter of silica gel. Non-imprinted polymer layer-coated silica gel (NIP@SiO2) and bulk molecularly imprinted polymer (MIP) were also prepared for comparison. Characterization and performance tests of the obtained products revealed that MIP@SiO2 not only had excellent selectivity to the target molecule MEL compared with NIP@SiO2, but also displayed absorption capacity superior to MIP due to the molecular recognition sites on the surface of silica gel. As the MIP@SiO2 were adopted as the adsorbents of solid-phase extraction for detecting MEL in milk samples, the recoveries of spiked samples ranged from 75.6% to 96.8% with the relative standard deviation of spiked samples less than 10%, which reveals that the MIP@SiO2 were efficient SPE adsorbents for melamine.
authors.affiliation: Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150001, China.
authors.forename: Wenjing
authors.initials: W
authors.lastname: Cheng
authors.forename: Zhujuan
authors.initials: Z
authors.lastname: Liu
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000327:Adsorption; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004785:Environmental Pollutants / Q000302:isolation & purification*; D057230:Limit of Detection; D008855:Microscopy, Electron, Scanning; D008892:Milk / Q000737:chemistry*; D054802:Molecular Imprinting / Q000295:instrumentation / Q000379:methods*; D011208:Powders; D058428:Silica Gel / Q000737:chemistry*; D052616:Solid Phase Extraction; D017550:Spectroscopy, Fourier Transform Infrared; D014227:Triazines / Q000302:isolation & purification*
chemical_list: D004785:Environmental Pollutants; D011208:Powders; D014227:Triazines; D058428:Silica Gel; C011907:melamine
keywords: Melamine; Molecularly imprinted polymer; Silica gel; Solid-phase extraction