title: Characterization of CRF56_cpx, a new circulating B/CRF02/G recombinant form identified in MSM in France.
abstract: Several B/CRF02_AG Unique Recombinant Forms (URFs) have previously been identified in France. Here we show that one of them (URF5_B/02/G) is emerging in MSM, a high-risk population where HIV incidence and number of superinfections are increasing. We describe this new Circulating Recombinant Form, CRF56_cpx, estimate the time to its most recent common ancestor, investigate its origins and show that it probably shares common ancestors with strains from the East Mediterranean.
authors.affiliation: aLaboratoire associé au CNR du VIH, hôpital Ch. Nicolle, CHU de Rouen bGRAM EA 2656, Faculté de Médecine-Pharmacie, Université de Rouen, Rouen, France cComputational and Evolutionary Biology research group, Faculty of Life Science, University of Manchester, Manchester, UK dAssistance Publique - Hopitaux de Paris, Groupe Hospitalier Bichat Claude Bernard, Service de Virologie eAssistance Publique - Hopitaux de Paris, Groupe Hospitalier Saint Louis, Service de Virologie, fAssistance Publique - Hopitaux de Paris, Groupe Hospitalier Pitié Salpêtrière, Service de Virologie, Paris, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Leoz
authors.forename: Felix
authors.initials: F
authors.lastname: Feyertag
authors.forename: Charlotte
authors.initials: C
authors.lastname: Charpentier
authors.forename: Constance
authors.initials: C
authors.lastname: Delaugerre
authors.forename: Marc
authors.initials: M
authors.lastname: Wirden
authors.forename: Veronique
authors.initials: V
authors.lastname: Lemee
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Plantier
mesh_terms: D000328:Adult; D016000:Cluster Analysis; D019143:Evolution, Molecular; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000453:epidemiology* / Q000821:virology*; D015497:HIV-1 / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D015994:Incidence; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA; D055815:Young Adult
chemical_list: D012367:RNA, Viral