title: Pretransplant mortality predictors in living and deceased donor liver transplantation.
abstract: BACKGROUND
  Although there were some reports predicting postoperative morbidity and mortality in patients undergoing liver transplantation, most of them studied deceased-donor liver transplantation (DDLT). In this context, we performed this study to predict early mortality after liver transplantation from preoperative variables in both living-donor liver transplantation (LDLT) and DDLT.
  
  
  METHODS
  We retrospectively reviewed the medical charts of 159 patients undergoing liver transplantation (LDLT, n = 103; DDLT, n = 56). Then, we identified the factors that independently predicted 30-day mortality using multivariable logistic regression models.
  
  
  RESULTS
  The 30-day mortality and 1-year mortality for DDLT versus LDLT were 30% versus 6% and 39% versus 11%, respectively. In multivariate logistic regression analysis, pretransplant hepatic encephalopathy (odds ratio, 5.594; 95% confidence interval, 1.110-28.194; p = 0.037) in patients with DDLT and serum creatinine (odds ratio, 4.883; 95% confidence interval, 1.296-18.399; p = 0.019) in patients with LDLT were the independent risk factors for a composite of 30-day mortality.
  
  
  CONCLUSIONS
  In conclusion, hepatic encephalopathy in DDLT and serum creatinine level in LDLT were the significant pretransplant variables that were related with early death after LT.
authors.affiliation: Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Incheon, South Korea.
authors.forename: Youn Yi
authors.initials: YY
authors.lastname: Jo
authors.affiliation: Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Yong Seon
authors.initials: YS
authors.lastname: Choi
authors.affiliation: Department of Surgery and The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Dong Jin
authors.initials: DJ
authors.lastname: Joo
authors.affiliation: Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Young-Chul
authors.initials: YC
authors.lastname: Yoo
authors.affiliation: Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Seung Gyun
authors.initials: SG
authors.lastname: Nam
authors.affiliation: Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, South Korea. Electronic address: sokoh@yuhs.ac.
authors.forename: Shin Ok
authors.initials: SO
authors.lastname: Koh
mesh_terms: D003404:Creatinine / Q000097:blood; D005260:Female; D005544:Forecasting; D006501:Hepatic Encephalopathy; D006801:Humans; D016031:Liver Transplantation / Q000401:mortality*; D019520:Living Donors; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014019:Tissue Donors
chemical_list: D003404:Creatinine
keywords: creatinine; hepatic encephalopathy; liver transplantation; mortality