title: Neutrophil to lymphocyte ratio as a measure of systemic inflammation in psoriasis.
abstract: OBJECTIVE
  Psoriasis is a chronic systemic inflammatory disorder. The neutrophil to lymphocyte ratio (N/L ratio) has been used as a marker for systemic inflammatory status. In our study, we aimed to evaluate N/L ratio in patients with psoriasis.
  
  
  METHODS
  This cross-sectional study population consisted of 138 patients with psoriasis and 120 age- and sex-matched control subjects.
  
  
  RESULTS
  The patients had significantly higher neutrophil counts and lower lymphocyte counts than the controls. The N/L ratios and high sensitivity C reactive protein (hs-CRP) levels were also significantly higher in patients. The N/L ratios and hs-CRP levels were increasing with increasing in Psoriasis Area and Severity Index score. Furthermore, the N/L ratios and hs-CRP levels of patients were found to be positively correlated.
  
  
  CONCLUSIONS
  Our data show that the N/L ratio to be a simple, inexpensive and easily assessable marker of systemic inflammation in patients with psoriasis.
authors.affiliation: Department of Dermatology and.
authors.forename: Bilge Bulbul
authors.initials: BB
authors.lastname: Sen
authors.forename: Emine Nur
authors.initials: EN
authors.lastname: Rifaioglu
authors.forename: Ozlem
authors.initials: O
authors.lastname: Ekiz
authors.forename: Mehmet Ugur
authors.initials: MU
authors.lastname: Inan
authors.forename: Tugba
authors.initials: T
authors.lastname: Sen
authors.forename: Nihat
authors.initials: N
authors.lastname: Sen
mesh_terms: D000328:Adult; D002097:C-Reactive Protein / Q000032:analysis; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007249:Inflammation / Q000276:immunology; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology*; D011565:Psoriasis / Q000097:blood / Q000453:epidemiology / Q000276:immunology*; D012720:Severity of Illness Index; D014421:Turkey / Q000453:epidemiology
chemical_list: D002097:C-Reactive Protein
keywords: Inflammation; neutrophil lymphocyte ratio; psoriasis