title: Analysis on 113 cases of adverse reactions caused by β-lactam antibiotics.
abstract: The objectives of this study were to learn about the characteristics and rules of the occurrence of adverse reactions caused by lactam antibiotics and provide a reference for clinical drug use.
  
  
  METHODS
  A retrospective study was made to analyse the 113 case reports of adverse reactions caused by β-lactam antibiotics collected in our hospital between 2007 and 2009.
  
  
  RESULTS
  113 cases of ADR involved 17 kinds of β-lactam antibiotics, headed by ceftriaxone sodium. The most common manifestation was skin and accessory damage; nervous system and gastrointestinal system damage were also easier to find, and the administration route was mainly intravenous infusion.
  
  
  CONCLUSIONS
  The clinical application of β-lactam antibiotics should pay attention to adverse reaction monitoring and rational drug use to reduce the incidence of adverse reactions.
authors.affiliation: Department of Orthopedics, Traditional Chinese Medicine Hospital of Qidong City, Jiangsu Pprovince, PR China, 226200.
authors.forename: Jianquan
authors.initials: J
authors.lastname: Lu
authors.forename: Chunyue
authors.initials: C
authors.lastname: Cai
authors.forename: Yufeng
authors.initials: Y
authors.lastname: Gu
authors.forename: Yanhui
authors.initials: Y
authors.lastname: Tang
authors.forename: Jinbiao
authors.initials: J
authors.lastname: Xue
authors.forename: Kaijian
authors.initials: K
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002443:Ceftriaxone / Q000009:adverse effects; D002648:Child; D005260:Female; D041981:Gastrointestinal Tract / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009420:Nervous System / Q000187:drug effects; D012189:Retrospective Studies; D012867:Skin / Q000187:drug effects; D055815:Young Adult; D047090:beta-Lactams / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000900:Anti-Bacterial Agents; D047090:beta-Lactams; D002443:Ceftriaxone
keywords: adverse drug reactions; β-lactam antibiotics