title: Sonographically guided core biopsy: a minimally invasive procedure for managing adnexal masses.
abstract: OBJECTIVE
  We hypothesized that sonographically guided core biopsy is an effective method for the differential diagnosis of adnexal masses and evaluated patients who underwent core biopsies in our gynecologic oncology department.
  
  
  METHODS
  We reviewed the medical records of 55 patients who underwent sonographically guided core biopsies in our gynecologic oncology department between 2010 and 2013. Patients with suspected ovarian malignancies who were unsuitable for optimal debulking surgery and patients at risk for higher morbidity and mortality because of a poor performance status, suspected nongynecologic tumors, and peritoneal tuberculosis were indicated for sonographically guided biopsy.
  
  
  RESULTS
  The indications for sonographically guided core biopsy were candidacy for suboptimal cytoreduction (n = 32 [58.2%]), a poor performance status (n = 11 [20.0%]), and suspected nongynecologic tumors (n = 12 [21.8%]). Histopathologic evaluations revealed primary ovarian tumors in 36 patients (65.5%). Tuberculosis was found to be the second most common disease (n = 8 [14.5%]) among the patients who underwent core biopsies. In 2 patients (3.6%), histologic examination revealed metastatic colorectal cancer.
  
  
  CONCLUSIONS
  Sonographically guided core biopsy may be preferred as a minimally invasive procedure for managing adnexal masses, particularly in patients with advanced ovarian cancer and high comorbidities who might benefit from neoadjuvant chemotherapy and in cases of suspected nongynecologic tumors, including pelvic tuberculosis.
authors.affiliation: Department of Obstetrics and Gynecology, Eskisehir Osmangazi University School of Medicine, 26100 Eskisehir, Turkey. tufanoge@yahoo.com.
authors.forename: Tufan
authors.initials: T
authors.lastname: Oge
authors.forename: Omer T
authors.initials: OT
authors.lastname: Yalcin
authors.forename: S Sinan
authors.initials: SS
authors.lastname: Ozalp
authors.forename: Mahmut
authors.initials: M
authors.lastname: Kebapci
authors.forename: Yunus
authors.initials: Y
authors.lastname: Aydin
authors.forename: Elcin
authors.initials: E
authors.lastname: Telli
mesh_terms: D000291:Adnexal Diseases / Q000000981:diagnostic imaging* / Q000473:pathology*; D062005:Biopsy, Large-Core Needle / Q000379:methods*; D005260:Female; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D018084:Ultrasonography, Interventional / Q000379:methods*; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology
keywords: advanced ovarian cancer; core biopsy; neoadjuvant chemotherapy; peritoneal tuberculosis; sonographically guided biopsy