title: Subcutaneous infusions of apomorphine: a reappraisal of its therapeutic efficacy in advanced Parkinson's disease.
abstract: Subcutaneous infusion of apomorphine is a useful treatment for motor and nonmotor complications in Parkinson's disease patients and improves the patient's quality of life. An adequate selection of suitable candidates is crucial for obtaining the best results with this therapy. Parkinsonian patients with severe biphasic dyskinesias, demented or having experienced serious neuropsychiatric side effects with other dopamine agonists should not be offered this treatment. The therapeutic effect of continuous apomorphine infusion is reviewed and practical recommendations on its use are provided.
authors.affiliation: Movement Disorders Research Unit, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Grandas
mesh_terms: D000818:Animals; D001058:Apomorphine / Q000008:administration & dosage / Q000627:therapeutic use*; D018491:Dopamine Agonists / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D055104:Infusions, Subcutaneous / Q000379:methods; D010300:Parkinson Disease / Q000188:drug therapy*; D011788:Quality of Life; D016896:Treatment Outcome
chemical_list: D018491:Dopamine Agonists; D001058:Apomorphine