title: Applications of nanomaterials in mass spectrometry analysis.
abstract: Mass spectrometry (MS) based analyses have received intense research interest in a series of rapidly developing disciplines. Although current MS techniques have enjoyed great successes, several key challenges still remain in practical applications, especially for the detection of biomolecules in biological systems. The use of nanomaterials in MS based analysis provides a promising approach due to their unique physical and chemical properties. In this review, nanomaterials with different compositions and nanostructures employed in MS applications are summarised and classified by their functions. Such an integrated and wide reaching review will provide a comprehensive handbook to researchers with various backgrounds working in this exciting interdisciplinary area.
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia. c.yu@uq.edu.au.
authors.forename: Chang
authors.initials: C
authors.lastname: Lei
authors.forename: Kun
authors.initials: K
authors.lastname: Qian
authors.forename: Owen
authors.initials: O
authors.lastname: Noonan
authors.forename: Amanda
authors.initials: A
authors.lastname: Nouwens
authors.forename: Chengzhong
authors.initials: C
authors.lastname: Yu
mesh_terms: D000818:Animals; D006031:Glycosylation; D006801:Humans; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods*; D049329:Nanostructures / Q000737:chemistry*; D010316:Particle Size; D010446:Peptide Fragments / Q000737:chemistry / Q000378:metabolism; D010750:Phosphoproteins / Q000737:chemistry / Q000378:metabolism; D010766:Phosphorylation; D059748:Proteolysis; D013048:Specimen Handling; D013379:Substrate Specificity
chemical_list: D010446:Peptide Fragments; D010750:Phosphoproteins