title: [Oral manifestations of systemic sclerosis].
abstract: Systemic sclerosis is a relatively rare connective tissue disorder, in which a severe and progressive fibrosis of the skin and sometimes also of internal organs often develops as a result of an increased deposition of collagen. Fibrosis of the salivary glands may cause hyposalivation and xerostomia. Fibrosis of the perioral skin reduces the maximum opening of the mouth, thereby hampering dental treatment and the maintenance of oral hygiene. Periodontitis and bone resorption ofthe jaws are more frequently observed in systemic sclerosis patients.
authors.affiliation: Uit de afdeling Reumatologie en Klinische Immunologie van bet Universitair Medisch Centrum Utrecht. j.m.van-laar@ncl.ac.uk
authors.forename: J M R
authors.initials: JM
authors.lastname: Michels-van Amelsfort
authors.forename: H S
authors.initials: HS
authors.lastname: Brand
authors.forename: J M
authors.initials: JM
authors.lastname: van Laar
mesh_terms: D001862:Bone Resorption / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D009059:Mouth Diseases / Q000453:epidemiology / Q000209:etiology; D009909:Oral Health; D010518:Periodontitis / Q000453:epidemiology / Q000209:etiology*; D012595:Scleroderma, Systemic / Q000150:complications*