title: Comparison of sirolimus-, paclitaxel-, and everolimus-eluting stent in unprotected left main coronary artery percutaneous coronary intervention.
abstract: OBJECTIVE
  This retrospective study evaluated the outcomes of patients who underwent unprotected left main coronary artery (ULMCA) percutaneous coronary intervention (PCI) with different types of drug-eluting stents (DES).
  
  
  BACKGROUND
  The standard of care for patients with ULMCA is coronary artery bypass surgery. However, current guidelines recommend PCI in clinical conditions where there is an increased risk of adverse surgical outcomes. Clinical outcomes of patients undergoing ULMCA PCI with different types of drug-eluting stents (DES) are unknown.
  
  
  METHODS
  Data from a multicenter international registry, which included 239 consecutive patients from four institutions who ULMCA PCI with DES, were collected.
  
  
  RESULTS
  There were 42 patients receiving paclitaxel-eluting stent (PES), 158 patients receiving sirolimus-eluting stent (SES), and 39 patients receiving everolimus-eluting stent (EES). There was no statistical difference in major adverse cardiovascular events, cardiac death, myocardial infarction, target lesion revascularization, and stent thrombosis among PES, SES, and EES at 30 days and 1 year.
  
  
  CONCLUSIONS
  There are no differences in clinical events among patients receiving PES, SES, and EES for ULMCA disease.
authors.affiliation: UCLA Medical Center, Los Angeles, CA, United States ; UCSD Medical Center, La Jolla, CA, United States ; Santa Barbara Cottage Hospital, Santa Barbara, CA, United States ; University of Turin - San Giovanni Battista "Molinette" Hospital, Turin, Italy.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Lee
authors.forename: Ehtisham
authors.initials: E
authors.lastname: Mahmud
authors.forename: Lawrence
authors.initials: L
authors.lastname: Ang
authors.forename: Gentian
authors.initials: G
authors.lastname: Lluri
authors.forename: Richard K
authors.initials: RK
authors.lastname: Cheng
authors.forename: Joseph
authors.initials: J
authors.lastname: Aragon
authors.forename: Imad
authors.initials: I
authors.lastname: Sheiban
keywords: Drug-eluting stent; Left main disease; Percutaneous coronary intervention