title: Consumption of three strong opioids (morphine, oxycodone and fentanyl) in seven European countries during seven years (2003-2009).
abstract: OBJECTIVE
  The aim was to analyse the consumption of selected strong opioid analgesics during a seven-year period of 2003-2009 in order to compare Slovak consumption with that in six other European countries and to determine our position.
  
  
  METHODS
  Drug consumption data from the State Institute for Drug Control in Slovak Republic were used. As to the data from other countries, annual health statistics published on websites were used in comparison.
  
  
  RESULTS
  Obviously the consumption of one of studied opioid drugs with transdermal aplication route, particularly fentanyl, tended to increase in all countries during the observed period. Oxycodone tends to yield a rapid increase in consumption as well. As opposed to the latter drugs, the consumption of morphine was decreasing throughout the observed period. The consumption of these drugs in Slovakia remains low (except for that of fentanyl).
  
  
  CONCLUSIONS
  Our analysis confirmed a clear shift from oral to transdermal therapy as well as usage of newer drugs. Drug consumption data are a relatively new source of information for health research. Our analysis showed increasing trends in fentanyl (patch opioid) consumption in all compared countries as well as an increasing consumption of oxycodone and decreasing consumption of morphine (Fig. 3, Ref. 17).
authors.forename: R
authors.initials: R
authors.lastname: Hudec
authors.forename: J
authors.initials: J
authors.lastname: Tisonova
authors.forename: V
authors.initials: V
authors.lastname: Foltan
authors.forename: V
authors.initials: V
authors.lastname: Kristova
mesh_terms: D000701:Analgesics, Opioid / Q000627:therapeutic use*; D004363:Drug Utilization / Q000706:statistics & numerical data*; D005060:Europe; D005283:Fentanyl / Q000627:therapeutic use*; D006801:Humans; D009020:Morphine / Q000627:therapeutic use*; D010098:Oxycodone / Q000627:therapeutic use*; D018154:Slovakia; D013997:Time Factors
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine; D010098:Oxycodone; D005283:Fentanyl
keywords: morphine, fentanyl, oxycodone, consumption, pain treatment.