title: Esotropia surgery in children with Down syndrome.
abstract: OBJECTIVE
  To evaluate postoperative alignment in children with and without Down syndrome after surgical correction of esotropia.
  
  
  METHODS
  The medical records of consecutive patients with Down syndrome who underwent corrective surgery for esotropia between August 1992 and July 2012 were retrospectively reviewed. Age range for eligibility was between 8 months and 17 years at surgery. The control group comprised randomly selected, age-matched patients without Down syndrome who underwent the same surgical procedure. Postoperative alignment within 10(Δ) of orthotropia at 6 months' follow-up and at the final postoperative visit was considered a successful outcome.
  
  
  RESULTS
  A total of 17 children with Down syndrome and 27 control subjects were included. The control group and Down syndrome group did not differ significantly in either postoperative follow-up (5.2 ± 3.2 versus 5.6 ± 5.2 years, respectively) or magnitude of deviation before surgery (40 ± 18.2(Δ) versus 39 ± 12.8(Δ), respectively). Surgical success was achieved in 76% of patients with Down syndrome and in 85% of control patients at 6 months' follow-up.
  
  
  CONCLUSIONS
  In this patient cohort, good surgical outcomes were achieved in children with esotropia and Down syndrome compared with those with esotropia but without Down syndrome using the same surgical technique.
authors.affiliation: Fundación Oftalmológica los Andes, Santiago, Chile; Universidad de los Andes, Santiago, Chile. Electronic address: ciperezv@gmail.com.
authors.forename: Claudio I
authors.initials: CI
authors.lastname: Perez
authors.forename: Francisca
authors.initials: F
authors.lastname: Zuazo
authors.forename: Mario T
authors.initials: MT
authors.lastname: Zanolli
authors.forename: Juan P
authors.initials: JP
authors.lastname: Guerra
authors.forename: Olga
authors.initials: O
authors.lastname: Acuña
authors.forename: Hernan
authors.initials: H
authors.lastname: Iturriaga
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications*; D004948:Esotropia / Q000209:etiology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009801:Oculomotor Muscles / Q000601:surgery; D016017:Odds Ratio; D012189:Retrospective Studies