title: Molecular switch based on very weak association between BPX26C6 and two recognition units.
abstract: A [2]rotaxane has been constructed through metal ion-templated pseudorotaxane formation from a weakly interacting host (bis-p-xylyl[26]crown-6)/guest (diphenylurea derivative) complex and post-assembly modification to form another weakly interacting tertiary ammonium ion recognition site for the host. The combination of this pair of weakly interacting components allowed bifunctional (pH, Na(+) ions) switching of the crown ether unit, highlighting the potential applicability of weakly associated components within molecular switches.
authors.affiliation: Department of Chemistry, National Taiwan University , No. 1, Sec. 4, Roosevelt Road, Taipei, 10617, Taiwan. R.O.C. , and Institute of Molecular Biology, National Chung Hsing University and Department of Medical Genetics, China Medical University Hospital , Taichung, Taiwan, R.O.C.
authors.forename: Tsan-Wen
authors.initials: TW
authors.lastname: Lu
authors.forename: Chia-Fong
authors.initials: CF
authors.lastname: Chang
authors.forename: Chien-Chen
authors.initials: CC
authors.lastname: Lai
authors.forename: Sheng-Hsien
authors.initials: SH
authors.lastname: Chiu
mesh_terms: D043844:Crown Ethers / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D043862:Rotaxanes / Q000737:chemistry*
chemical_list: D043844:Crown Ethers; D043862:Rotaxanes; C529529:bis-4-xylyl(26)crown-6