title: Photocatalytic antibacterial effects are maintained on resin-based TiO2 nanocomposites after cessation of UV irradiation.
abstract: Photocatalysis induced by TiO2 and UV light constitutes a decontamination and antibacterial strategy utilized in many applications including self-cleaning environmental surfaces, water and air treatment. The present work reveals that antibacterial effects induced by photocatalysis can be maintained even after the cessation of UV irradiation. We show that resin-based composites containing 20% TiO2 nanoparticles continue to provide a pronounced antibacterial effect against the pathogens Escherichia coli, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus mutans and Enterococcus faecalis for up to two hours post UV. For biomaterials or implant coatings, where direct UV illumination is not feasible, a prolonged antibacterial effect after the cessation of the illumination would offer new unexplored treatment possibilities.
authors.affiliation: Division for Nanotechnology and Functional Materials, Department of Engineering Sciences, The Ångström Laboratory, Uppsala University, Uppsala, Sweden.
authors.forename: Yanling
authors.initials: Y
authors.lastname: Cai
authors.forename: Maria
authors.initials: M
authors.lastname: Strømme
authors.forename: Ken
authors.initials: K
authors.lastname: Welch
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology* / Q000528:radiation effects; D002384:Catalysis; D013293:Enterococcus faecalis / Q000187:drug effects / Q000254:growth & development; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D050296:Microbial Viability / Q000187:drug effects; D053761:Nanocomposites / Q000737:chemistry / Q000528:radiation effects*; D053758:Nanoparticles / Q000737:chemistry / Q000528:radiation effects*; D055668:Photochemical Processes; D012117:Resins, Synthetic / Q000737:chemistry / Q000494:pharmacology* / Q000528:radiation effects; D013212:Staphylococcus epidermidis / Q000187:drug effects / Q000254:growth & development; D013295:Streptococcus mutans / Q000187:drug effects / Q000254:growth & development; D013297:Streptococcus pyogenes / Q000187:drug effects / Q000254:growth & development; D013997:Time Factors; D014025:Titanium / Q000737:chemistry / Q000494:pharmacology* / Q000528:radiation effects; D014466:Ultraviolet Rays
chemical_list: D000900:Anti-Bacterial Agents; D012117:Resins, Synthetic; C009495:titanium dioxide; D014025:Titanium