title: TSH-Secreting Pituitary Macroadenoma in a Girl with Lingual Thyroid.
abstract: Patients with long-standing hypothyroid are, in some cases, reported to develop pituitary gland hyperplasia due to loss of feedback inhibition of thyroxine in hypothalamus-the condition of which typically regresses after thyroxine replacement. Herein, a 15-year-old girl-with long-standing untreated lingual hypothyroid-presents with a pathologically proven TSH pituitary macroadenoma and bilateral large ovarian cysts. Although MR imaging may differentiate between hyperplasia and macroadenoma of the pituitary gland, pathological examination is still a cornerstone to correct diagnosis.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Wacharasindhu
authors.forename: S
authors.initials: S
authors.lastname: Shuangshoti
authors.forename: S
authors.initials: S
authors.lastname: Sunthornyothin