title: [Lupus nephropathy in black patients with systemic lupus erythematosus in Senegal: 43 cases].
abstract: This study sought to assess the prevalence of lupus nephropathy and to determine its clinical, histological, therapeutic and outcome profiles.
  
  
  METHODS
  This retrospective study examined records covering a 10-year period from 1999 to 2009 at the nephrology department of the Aristide Le Dantec University Hospital Center.
  
  
  RESULTS
  The records showed 43 patients with systemic lupus erythematosus (SLE), and 72% had lupus nephritis. The patients' mean age was 32.9 years; 40 were women and 3 men, for a sex ratio of 0.075. The lupus nephritis led to discovery of SLE in 27.9%. The mean proteinuria concentration was 2.01 g/dL. Seventeen patients had impaired renal function, and 26 had renal biopsies. It found class II nephritis in 2 patients, class IV in 10, and class V in 12. In addition, fifteen patients received combined corticosteroid + immunosuppressant treatment. Four patients died during the study period, one from SLE activity, two from complications of renal failure, and the fourth from sepsis.
  
  
  CONCLUSIONS
  A larger study would be useful to assess more acurately the prevalence of various classes and severity of lupus nephropathy among blacks living in sub-Saharan Africa.
authors.affiliation: Service de néphrologie.
authors.forename: E F
authors.initials: EF
authors.lastname: Ka
authors.forename: M M
authors.initials: MM
authors.lastname: Cisse
authors.forename: A T
authors.initials: AT
authors.lastname: Lemrabott
authors.forename: S
authors.initials: S
authors.lastname: Fall
authors.forename: M
authors.initials: M
authors.lastname: Diallo
authors.forename: S
authors.initials: S
authors.lastname: Diallo
authors.forename: M
authors.initials: M
authors.lastname: Faye
authors.forename: A
authors.initials: A
authors.lastname: Niang
authors.forename: B
authors.initials: B
authors.lastname: Diouf
mesh_terms: D000328:Adult; D044383:Black People; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000453:epidemiology*; D008181:Lupus Nephritis / Q000145:classification / Q000453:epidemiology*; D008297:Male; D015995:Prevalence; D011507:Proteinuria / Q000209:etiology; D012189:Retrospective Studies; D012675:Senegal
keywords: Senegal; lupus; nephropathy