title: [Tuberculosis and HIV co-infection: clinical trial under the coordination of the Institut Pasteur in Cambodia].
abstract: Tuberculosis is a major cause of death among adults infected by HIV. The CAMELIA (ANRS 1295/CIPRA KH001) randomized clinical trial aimed to determine the optimal timing of ARV initiation after tuberculosis treatment onset to reduce mortality. Here, we describe the trial implementation in five hospitals in Cambodia under the coordination of the Institut Pasteur in Cambodia, its conduct, the challenges and public health benefits in Cambodia and beyond.
authors.affiliation: Unité d'épidémiologie et de santé publique, Institut Pasteur du Cambodge, 5 boulevard Monivong, Phnom Penh, Cambodge.
authors.forename: Laurence
authors.initials: L
authors.lastname: Borand
authors.forename: Phearavin
authors.initials: P
authors.lastname: Pheng
authors.forename: Manil
authors.initials: M
authors.lastname: Saman
authors.forename: Chanthy
authors.initials: C
authors.lastname: Leng
authors.forename: Phalla
authors.initials: P
authors.lastname: Chea
authors.forename: Sao
authors.initials: S
authors.lastname: Sarady Ay
authors.forename: Sophea
authors.initials: S
authors.lastname: Suom
authors.forename: Nimul
authors.initials: N
authors.lastname: Roat Men
authors.forename: Eric
authors.initials: E
authors.lastname: Nerrienet
authors.forename: Olivier
authors.initials: O
authors.lastname: Marcy
mesh_terms: D000047:Academies and Institutes / Q000458:organization & administration*; D000328:Adult; D044966:Anti-Retroviral Agents / Q000008:administration & dosage; D000995:Antitubercular Agents / Q000008:administration & dosage; D002160:Cambodia; D060085:Coinfection; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology / Q000628:therapy*; D015497:HIV-1 / Q000502:physiology; D006801:Humans; D007391:International Cooperation; D016032:Randomized Controlled Trials as Topic; D014376:Tuberculosis / Q000150:complications / Q000453:epidemiology / Q000628:therapy*
chemical_list: D044966:Anti-Retroviral Agents; D000995:Antitubercular Agents