title: Prevalence of positive culture of genitourinary tract microorganisms in pregnant women with presumptive preterm labor.
abstract: BACKGROUND
  Cultures of genitourinary tract microorganisms have been included in routine evaluation for all pregnant women who present with presumptive preterm labor However some studies found that this assessment is costly and adds little value.
  
  
  OBJECTIVE
  To determine the proportion of pregnant women with presumptive preterm labor who had positive culture of genitourinary tract microorganisms and to determine the relationship of positive genitourinary infection and pregnancy outcomes.
  
  
  METHODS
  This retrospective cohort study was performed at Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital, Mahidol University. Medical records of pregnant women with presumptive preterm labor who were admitted in non-private labor room between January 2003 and December 2008 were reviewed Characteristics, results of vaginal swab culture and urine culture, and clinical outcomes were analyzed and reported.
  
  
  RESULTS
  The prevalence of positive culture of genitourinary tract microorganisms in presumptive preterm labor-women (total n = 704) was 24.3% (95% CI = 21.3-27.6), 22.1% (95% CI = 19.1-25.4) of vaginal swab culture and 5.3% (95% CI = 3.8-7.2) of urine culture. However only 9.8% were pathologic organisms. There were no statistically significant differences in characteristics and rate of preterm labor between women with a positive and a negative culture. Moreover, there were no statistically significant differences in characteristics and preterm birth outcomes between women in both groups.
  
  
  CONCLUSIONS
  There were no clinical significances of positivity of pathologic bacteria from genitourinary tract as a predictor of preterm delivery and its outcomes. Although the prevalence is quite high, the value of these screenings is still questionable.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. siacl@mahidolac.th
authors.forename: Amphan
authors.initials: A
authors.lastname: Chalermchockchareonkit
authors.forename: Sukhumarn
authors.initials: S
authors.lastname: Phoethong
authors.forename: Pornpimol
authors.initials: P
authors.lastname: Ruangvutilert
authors.forename: Manopchai
authors.initials: M
authors.lastname: Thamkhantho
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007752:Obstetric Labor, Premature; D011237:Predictive Value of Tests; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000382:microbiology*; D011256:Pregnancy Outcome; D015995:Prevalence; D012189:Retrospective Studies; D013785:Thailand / Q000453:epidemiology; D016482:Urinalysis; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000382:microbiology*