title: A comparison of dentifrices for clinical relief from dentin hypersensitivity using the Jay Sensitivity Sensor Probe.
abstract: OBJECTIVE
  To evaluate the clinical relief from dentin hypersensitivity among subjects provided with a dentifrice formulated with 8% arginine, calcium carbonate and 1,000 ppm fluoride [sodium monofluorophosphate (MFP)] in comparison to those issued a commercially available dentifrice containing 1,000 ppm fluoride [as sodium monofluorophosphate (MFP)]. Clinical evaluations for hypersensitivity were performed with a novel tactile hypersensitivity measuring instrument--the Jay Sensitivity Sensor (Jay) Probe--in conjunction with evaporative triggers by air blast (Schiff scale) and Visual Analog Scores (VAS).
  
  
  METHODS
  Qualified adults from the Mangalore, India area who presented two teeth with dentin hypersensitivity were enrolled for this double-blind, randomized, parallel, controlled clinical trial conducted in an outpatient clinical setting. At baseline, dentin hypersensitivity was evaluated by the Jay Probe (tactile), air blast and VAS methods. Subjects were randomly issued a study dentifrice and instructed to brush their teeth for 1 minute twice daily with the provided dentifrice. Clinical evaluations for hypersensitivity were repeated after 2, 4 and 8 weeks of product use.
  
  
  RESULTS
  86 subjects (35 males and 51 females) complied with the study protocol and completed the entire study. At each recall visit, both treatment groups demonstrated significant reductions in dentin hypersensitivity from their corresponding baselines (P < 0.05). Subjects assigned the 8% arginine, calcium carbonate and 1,000 ppm fluoride dentifrice demonstrated statistically significant reductions in responses to tactile stimuli, air blast, and VAS responses in comparison to those using the dentifrice containing 1,000 ppm fluoride after 2, 4, and 8 weeks, respectively.
authors.affiliation: Department of Periodontics, Yenepova Dental College, Magalore, India.
authors.forename: Shashikanth
authors.initials: S
authors.lastname: Hegde
authors.forename: B H Sripathi
authors.initials: BH
authors.lastname: Rao
authors.forename: Ravish Chander
authors.initials: RC
authors.lastname: Kakar
authors.forename: Ashish
authors.initials: A
authors.lastname: Kakar
mesh_terms: D000328:Adult; D000388:Air; D001120:Arginine / Q000627:therapeutic use; D002119:Calcium Carbonate / Q000627:therapeutic use; D003802:Dentifrices / Q000627:therapeutic use*; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000175:diagnosis / Q000517:prevention & control*; D019719:Diagnostic Equipment; D004311:Double-Blind Method; D004867:Equipment Design; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008838:Microcomputers; D008875:Middle Aged; D010147:Pain Measurement; D010710:Phosphates / Q000627:therapeutic use; D010812:Physical Stimulation; D014110:Touch; D014160:Transducers, Pressure; D055815:Young Adult
chemical_list: D003802:Dentifrices; D057133:Dentin Desensitizing Agents; D010710:Phosphates; C012980:fluorophosphate; D001120:Arginine; D002119:Calcium Carbonate; D005459:Fluorides