title: Comparative analysis of ABO-incompatible living donor kidney transplantation with ABO-compatible grafts: a single-center experience in Korea.
abstract: BACKGROUND
  Serious organ shortages have necessitated the use of ABO-incompatible (ABOi) kidneys transplantation, which has been increasingly preformed in Korea. However there are few detailed comparative data regarding patient and graft survival, graft function, and complications in Korean patients receiving ABO-compatible (ABOc) and ABOi kidney transplants (KT).
  
  
  METHODS
  This retrospective study compared 35 consecutive ABOi living donor KTs with 138 ABOc living donor KTs using same immunosuppressive regimens. We examined preoperative demographic factors, immunologic risk factors, patient and graft survivals, postoperative renal function, acute rejection episodes, infections, medical and surgical complications, duration of hospital stay as well as cause for readmission, and their rates.
  
  
  RESULTS
  Patient survival, graft survival, and graft function over the 2 years after transplantation were similar between the 2 groups. There were no significant differences in terms of complications with exception of bleeding and BK virus infection. Acute antibody-mediated rejection episodes, bleeding complications, BK virus infections, and preoperative hospital stay were significantly greater in the ABOi group (P = .001, P = .002, P = .005, and P < .001 respectively).
  
  
  CONCLUSIONS
  We concluded that, despite some disadvantages, ABOi KT is a viable, safe option for patients whose only available donor is blood group incompatible.
authors.affiliation: Department of Surgery, Dajeon St Mary's Hospital, Seoul St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea.
authors.forename: J-K
authors.initials: JK
authors.lastname: Hwang
authors.forename: Y-K
authors.initials: YK
authors.lastname: Kim
authors.forename: J-M
authors.initials: JM
authors.lastname: Kim
authors.forename: B-H
authors.initials: BH
authors.lastname: Chung
authors.forename: B-S
authors.initials: BS
authors.lastname: Choi
authors.forename: C-W
authors.initials: CW
authors.lastname: Yang
authors.forename: Y-S
authors.initials: YS
authors.lastname: Kim
authors.forename: I-S
authors.initials: IS
authors.lastname: Moon
authors.forename: J-I
authors.initials: JI
authors.lastname: Kim
mesh_terms: D000017:ABO Blood-Group System; D000328:Adult; D005260:Female; D006085:Graft Survival; D006650:Histocompatibility Testing; D006801:Humans; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D056910:Republic of Korea; D016019:Survival Analysis
chemical_list: D000017:ABO Blood-Group System