title: Inhibitory effect of saponins and polysaccharides from Radix ranunculi ternati on human gastric cancer BGC823 cells.
abstract: The effects of different Radix ranunculi ternati extracts on human gastric cancer BGC823 cells were investigated, different methods were used to extract the saponins and polysaccharides from Radix ranunculi ternati, and MTT assay and colony formation assay were used to observe the effects of saponins and polysaccharides from Radix ranunculi ternati on in-vitro cultured human gastric cancer BGC823 cells. The results found that the saponins and polysaccharides from Radix Ranunculi Ternati had certain effects on both the growth and colony formation of human gastric cancer BGC823 cells, while improving the immune function of normal mice, of which saponins had more significant effects than polysaccharides.
authors.affiliation: The First Affiliated Hospital of Xinxiang Medical University.
authors.forename: Lidan
authors.initials: L
authors.lastname: Niu
authors.forename: Yingfeng
authors.initials: Y
authors.lastname: Zhou
authors.forename: Bing
authors.initials: B
authors.lastname: Sun
authors.forename: Junling
authors.initials: J
authors.lastname: Hu
authors.forename: Lingyu
authors.initials: L
authors.lastname: Kong
authors.forename: Sufang
authors.initials: S
authors.lastname: Duan
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology / Q000627:therapeutic use*; D045744:Cell Line, Tumor; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007109:Immunity / Q000187:drug effects; D008517:Phytotherapy; D018517:Plant Roots; D011134:Polysaccharides / Q000494:pharmacology / Q000627:therapeutic use*; D031947:Ranunculus / Q000737:chemistry*; D012503:Saponins / Q000494:pharmacology / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000188:drug therapy*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D011134:Polysaccharides; D012503:Saponins
keywords: Radix Ranunculi Ternati; human gastric cancer BGC823 cells; polysaccharide; saponin