title: Chemical reconstruction of skin scars therapy using 100% trichloroacetic Acid in the treatment of atrophic facial post varicella scars: a pilot study.
abstract: BACKGROUND
  Chickenpox (varicella) is a common viral disease caused by Varicella zoster virus. Facial atrophic scars after varicella infection are not uncommon and pose a cosmetic problem. Like atrophic scars of other aetiologies, they are a difficult condition to treat. There are not enough references in the literature regarding efficient treatment of post varicella scars. High strength Trichloroacetic acid (TCA), which is known to cause dermal collagen remodelling, was used to treat varicella scars in the present study.
  
  
  OBJECTIVE
  The study was undertaken to assess the efficiency of Chemical Reconstruction of Skin Scars (CROSS) technique using 100% TCA in the treatment of atrophic facial post varicella scars.
  
  
  METHODS
  Open label, pilot study.
  
  
  METHODS
  A total of 16 patients with atrophic facial post varicella scars were treated by focal application of 100% TCA solution by pressing down upon the scar surface by a toothpick (CROSS technique). Total 4 sittings were given at 2 weekly intervals and the results evaluated after 3 months of follow-up. Statistical analysis was carried out using Fischer's exact t-test.
  
  
  RESULTS
  All of the 13 patients who completed the study showed good clinical improvement, with 69% patients grading the response as excellent (>75%) improvement, whereas the rest 31% patients reporting good (51-75%) improvement. No significant complications were seen in any patient.
  
  
  CONCLUSIONS
  CROSS technique using 100% TCA is a safe, cheap and effective therapy for the treatment of post varicella scars.
authors.affiliation: Department of Dermatology, RNT Medical College, Udaipur, Rajasthan, India.
authors.forename: Nidheesh
authors.initials: N
authors.lastname: Agarwal
authors.forename: Asit
authors.initials: A
authors.lastname: Mittal
authors.forename: Cm
authors.initials: C
authors.lastname: Kuldeep
authors.forename: Lalit Kumar
authors.initials: LK
authors.lastname: Gupta
authors.forename: Ashok Kumar
authors.initials: AK
authors.lastname: Khare
authors.forename: Sharad
authors.initials: S
authors.lastname: Mehta
keywords: Chemical reconstruction of skin scars; scar; trichloroacetic acid; varicella