title: A split mouth randomized controlled study to evaluate the adjunctive effect of platelet-rich fibrin to coronally advanced flap in Miller's class-I and II recession defects.
abstract: BACKGROUND
  There are various techniques developed to treat the exposed roots, a recent innovation in dentistry is the use of second generation platelet concentrate which is an autologous platelet-rich fibrin gel (PRF) with growth factors and cicatricial properties for root coverage procedures. Therefore, the present research was undertaken to study the additional benefits of PRF when used along with coronally advanced flap (CAF).
  
  
  METHODS
  Total of 15 systemically healthy subjects presenting bilateral isolated Miller's class I and II recession were enrolled into the study. Each patient was randomly treated with a combination of CAF along with a platelet-rich fibrin (PRF) membrane on the test site and CAF alone on the control site. Recession depth, clinical attachment level (CAL), and width of keratinized gingiva (WKG) were compared with baseline at 1, 3, and 6 months between test and control sites.
  
  
  RESULTS
  Mean percentage root coverage in the test group after 1, 3, and 6 months was 34.58, 70.73, and 100, respectively. Differences between the control and test groups were statistically significant. This study also showed a statistically significant increase in WKG in the test group (2.94 ± 0.77 at baseline to 5.38 ± 1.67 at 6 months).
  
  
  CONCLUSIONS
  CAF is a predictable treatment for isolated Miller's class I and II recession defects. The addition of PRF membrane with CAF provides superior root coverage with additional benefits of gain in CAL and WKG at 6 months postoperatively.
authors.affiliation: Department of Periodontics, Coorg Institute of Dental Sciences, K.K. Campus, Maggula, Virajpet, Coorg, Karnataka, India.
authors.forename: Rajan
authors.initials: R
authors.lastname: Padma
authors.forename: Ande
authors.initials: A
authors.lastname: Shilpa
authors.forename: Pavaluri Aravind
authors.initials: PA
authors.lastname: Kumar
authors.forename: Meganderao
authors.initials: M
authors.lastname: Nagasri
authors.forename: Chetan
authors.initials: C
authors.lastname: Kumar
authors.forename: Annaji
authors.initials: A
authors.lastname: Sreedhar
keywords: Coronally advanced flap; gingival recession; platelet rich fibrin; root coverage procedures