title: Hepatitis C virus late relapse after sustained virologic response from interferon and ribavirin treatment as confirmed by RNA sequencing.
abstract: Hepatitis C virus (HCV) viremia is unusual (<5%) after successful treatment, defined as sustained virologic response (SVR) or undetectable HCV PCR 12 to 24 weeks after therapy. We present a case of late virologic relapse (de novo infection was excluded by RNA sequencing) after SVR followed by spontaneous viral clearance.
authors.affiliation: Division of Gastroenterology, McGill University Health Center, McGill University, Montreal, Quebec, Canada.
authors.forename: Yidan
authors.initials: Y
authors.lastname: Lu
authors.forename: Anton
authors.initials: A
authors.lastname: Andonov
authors.forename: David K H
authors.initials: DK
authors.lastname: Wong
mesh_terms: D016000:Cluster Analysis; D005260:Female; D016174:Hepacivirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D006526:Hepatitis C / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D007372:Interferons / Q000627:therapeutic use*; D008875:Middle Aged; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D012008:Recurrence; D012254:Ribavirin / Q000627:therapeutic use*; D017423:Sequence Analysis, RNA; D017385:Sequence Homology; D014759:Viral Envelope Proteins / Q000235:genetics; D014766:Viremia / Q000175:diagnosis* / Q000821:virology
chemical_list: C087035:E1 protein, Hepatitis C virus; D012367:RNA, Viral; D014759:Viral Envelope Proteins; D012254:Ribavirin; D007372:Interferons