title: Incidence and outcome of cerebrovascular events related to cervical artery dissection: the Dijon Stroke Registry.
abstract: BACKGROUND
  Reliable epidemiological data on the true incidence of cerebrovascular events related to spontaneous cervical artery dissection, including stroke and transient ischemic attack, are scarce.
  
  
  OBJECTIVE
  To evaluate the incidence, characteristics, and outcome of cerebrovascular events due to cervical artery dissection.
  
  
  METHODS
  All cerebrovascular events (stroke and transient ischemic attack) occurring in Dijon, France, from 2006 to 2011, were retrieved from a population-based registry. Patients with a cervical artery dissection were identified. Incidence rates, baseline characteristics, and outcome at three-months were described.
  
  
  RESULTS
  Among the 1368 patients with cerebrovascular events, 27 had cervical artery dissection (2·0%, 52% men, mean age 49·1±17·1), including 10 patients with internal carotid artery dissection, 16 patients with vertebral artery dissection, and one patients with both internal carotid artery dissection and vertebral artery dissection. The crude incidence rate of cerebrovascular events due to cervical artery dissection was 2·97/100,000/year. Corresponding rates were 1·21/100,000/year for internal carotid artery dissection, and 1·87/100,000/year for vertebral artery dissection. Seventy per cent of patients had a stroke and among these, higher severity was observed in those with internal carotid artery dissection. A good outcome (m-Rankin score 0-2) was observed in 89% of patients at three-months, whatever the location of the cervical artery dissection. One patient with vertebral artery dissection died at day 38.
  
  
  CONCLUSIONS
  The incidence of cerebrovascular events related to vertebral artery dissection is greater than previously reported, which may indicate a better identification of patients due to improvements in diagnostic procedures.
authors.affiliation: Dijon Stroke Registry, EA4184, University Hospital, Medical School of Dijon, University of Burgundy, Dijon, France.
authors.forename: Yannick
authors.initials: Y
authors.lastname: Béjot
authors.forename: Benoit
authors.initials: B
authors.lastname: Daubail
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Debette
authors.forename: Jérôme
authors.initials: J
authors.lastname: Durier
authors.forename: Maurice
authors.initials: M
authors.lastname: Giroud
mesh_terms: D020215:Carotid Artery, Internal, Dissection / Q000150:complications / Q000453:epidemiology* / Q000503:physiopathology / Q000628:therapy; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D002546:Ischemic Attack, Transient / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012042:Registries; D020521:Stroke / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D020217:Vertebral Artery Dissection / Q000150:complications / Q000453:epidemiology* / Q000503:physiopathology / Q000628:therapy
keywords: acute stroke; cervical artery dissection; epidemiology; incidence; outcome; registry