title: Presentation and revascularization patterns of patients admitted for acute coronary syndromes in France between 2004 and 2008 (from the National Observational Study of Diagnostic and Interventional Cardiac Catheterization [ONACI]).
abstract: Patients with acute coronary syndrome (ACS) comprise a heterogeneous group. Despite clear guidelines, the management of ACS in clinical practice is variable. We aimed to evaluate clinical characteristics and myocardial revascularization patterns of patients presenting with ACS from a large French nationwide registry. The National Observational Study of Diagnostic and Interventional Cardiac Catheterization is a multicenter registry including all interventional cardiology procedures performed since 2004. Patient demographics and co-morbidities, invasive parameters, treatment options, and procedural techniques were prospectively collected. The present study is focused on data collected between 2004 and 2008. Patients were recruited in 99 hospitals (55% in private clinics, 45% in public institutions). Over a 5-year period, 64,932 patients with ACS were included (mean age 65.7 ± 13.3; 73% men, 31% ST-elevation myocardial infarction [STEMI]). Patients presenting with unstable angina pectoris and non-ST-elevation myocardial infarction weresimilar with regards to clinical presentation and coronary artery disease (CAD) extension. Overall, these patients were older, had a higher cardiovascular risk profile, and had more severe CAD compared with STEMI patients. In-hospital mortality during the first 24 hours was higher in STEMI patients. Patient's characteristics and CAD were highly dependent on the type of ACS. Patients with unstable angina/non-STEMI were older and had a more severe CAD. In-hospital complications were higher in STEMI patients.
authors.affiliation: Department of Cardiology, Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, France; Université Paris Descartes, Paris, France; Department of Biomedical and Surgical Sciences, Cardiology Section, University of Verona, Verona, Italy.
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: Donataccio
authors.forename: M
authors.initials: M
authors.lastname: PiaDonataccio
authors.affiliation: Department of Cardiology, Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, France; Université Paris Descartes, Paris, France; INSERM U970, Paris Cardiovascular Research Center PARCC, Paris, France. Electronic address: etiennepuymirat@yahoo.fr.
authors.forename: Etienne
authors.initials: E
authors.lastname: Puymirat
authors.affiliation: Department of Biomedical and Surgical Sciences, Cardiology Section, University of Verona, Verona, Italy.
authors.forename: Corrado
authors.initials: C
authors.lastname: Vassanelli
authors.affiliation: Department of Cardiology, Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, France; Université Paris Descartes, Paris, France.
authors.forename: Didier
authors.initials: D
authors.lastname: Blanchard
authors.affiliation: Department of Cardiology, University Hospital of Rennes, Rennes, France.
authors.forename: Hervé
authors.initials: H
authors.lastname: le Breton
authors.affiliation: INSERM U970, Paris Cardiovascular Research Center PARCC, Paris, France.
authors.forename: Marie-Cécile
authors.initials: MC
authors.lastname: Perier
authors.affiliation: Department of Cardiology, University Hospital of Brest, Brest, France.
authors.forename: Martine
authors.initials: M
authors.lastname: Gilard
authors.affiliation: Department of Cardiology, Institut hospitalier Jacques Cartier, Massy, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Lefèvre
authors.affiliation: Department of Cardiology, Clinique les Fleurs, Ollioules, France.
authors.forename: Paul
authors.initials: P
authors.lastname: Barragan
authors.affiliation: Société Française de Cardiologie, Paris, France.
authors.forename: Geneviève
authors.initials: G
authors.lastname: Mulak
authors.affiliation: Department of Cardiology, Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, France; Université Paris Descartes, Paris, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Danchin
authors.affiliation: Department of Cardiology, Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, France; Université Paris Descartes, Paris, France; INSERM U970, Paris Cardiovascular Research Center PARCC, Paris, France.
authors.forename: Christian
authors.initials: C
authors.lastname: Spaulding
authors.affiliation: Department of Cardiology, Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, France; Université Paris Descartes, Paris, France; INSERM U970, Paris Cardiovascular Research Center PARCC, Paris, France.
authors.forename: Xavier
authors.initials: X
authors.lastname: Jouven
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D054058:Acute Coronary Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D006328:Cardiac Catheterization / Q000379:methods; D017023:Coronary Angiography; D004562:Electrocardiography; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D017052:Hospital Mortality / Q000639:trends; D015994:Incidence; D009204:Myocardial Revascularization / Q000379:methods; D011183:Postoperative Complications / Q000453:epidemiology; D011379:Prognosis; D011446:Prospective Studies; D012042:Registries; D012307:Risk Factors; D015996:Survival Rate / Q000639:trends