title: Plasma exchange and ribavirin for rapidly progressive severe fever with thrombocytopenia syndrome.
abstract: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease caused by a novel bunyavirus. Although the increasing numbers of cases and deaths is of great concern, an effective treatment strategy for SFTS has not been established. We present the cases of two patients with rapidly progressing SFTS who were successfully treated with plasma exchange and ribavirin.
authors.affiliation: Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea.
authors.forename: Won Sup
authors.initials: WS
authors.lastname: Oh
authors.affiliation: Department of Internal Medicine, Jeju National University School of Medicine, 102 Jejudaehakno, Jeju-si, Jeju Special Self-Governing Province, 690-756, Korea. Electronic address: neosangtaek@naver.com.
authors.forename: Sang Taek
authors.initials: ST
authors.lastname: Heo
authors.affiliation: Department of Laboratory Medicine, Jeju National University School of Medicine, Jeju, Korea.
authors.forename: Sun Hyung
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Epidemic Intelligence Service Officer, Division of Health and Sanitation, Jeju, Korea.
authors.forename: Won Jun
authors.initials: WJ
authors.lastname: Choi
authors.affiliation: Division of Arboviruses, Center for Immunology and Pathology, National Institute of Health, Cheongwon, Korea.
authors.forename: Myung Guk
authors.initials: MG
authors.lastname: Han
authors.affiliation: Department of Internal Medicine, Jeju National University School of Medicine, 102 Jejudaehakno, Jeju-si, Jeju Special Self-Governing Province, 690-756, Korea.
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Kim
mesh_terms: D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use*; D002044:Bunyaviridae Infections / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D016851:Orthobunyavirus; D010951:Plasma Exchange; D056910:Republic of Korea; D012254:Ribavirin / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D012254:Ribavirin
keywords: Bunyavirus; Plasma exchange; Ribavirin; Severe fever with thrombocytopenia syndrome