title: Enhanced antibacterial activity of silver/polyrhodanine-composite-decorated silica nanoparticles.
abstract: This work describes the synthesis of silver/polyrhodanine-composite-decorated silica nanoparticles and their antibacterial activity. Polymerization of polyrhodanine proceeded preferentially on the surface of the silica nanoparticles where Ag(+) ions were located. In addition, the embedded Ag(+) ions were reduced to form metallic Ag nanoparticles; consequently, silver/polyrhodanine-composite nanoparticles (approximately 7 nm in diameter) were formed on the surface of the silica nanoparticles. The resulting nanostructure was investigated using electron microscopy, Fourier-transform infrared spectroscopy, ultraviolet-visible spectroscopy, and X-ray photoelectron spectroscopy. The silver/polyrhodanine-nanocomposite-decorated silica nanoparticles exhibited excellent antimicrobial activity toward gram-negative Escherichia coli and gram-positive Staphylococcus aureus because of the antibacterial effects of the silver nanoparticles and the polyrhodanine. The silver/polyrhodanine-composite nanoparticles may therefore have potential for use as a long-term antibacterial agent.
authors.affiliation: WCU Program of Chemical Convergence for Energy and Environment (C2E2), School of Chemical and Biological Engineering, College of Engineering, Seoul National University , 599 Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea.
authors.forename: Jooyoung
authors.initials: J
authors.lastname: Song
authors.forename: Hyunyoung
authors.initials: H
authors.lastname: Kim
authors.forename: Yoonsun
authors.initials: Y
authors.lastname: Jang
authors.forename: Jyongsik
authors.initials: J
authors.lastname: Jang
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D053761:Nanocomposites / Q000737:chemistry / Q000648:ultrastructure; D012822:Silicon Dioxide / Q000737:chemistry / Q000494:pharmacology; D012834:Silver / Q000737:chemistry / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000254:growth & development*
chemical_list: D000900:Anti-Bacterial Agents; D012834:Silver; D012822:Silicon Dioxide