title: Vibration response imaging versus perfusion scan in lung cancer surgery evaluation.
abstract: OBJECTIVE
  Ventilation/perfusion scan is a standard procedure in high-risk surgical patients to predict pulmonary function after surgery. Vibration response imaging is a technique that could be used in these patients. The objective of our study was to compare this imaging technique with the usual scanning technique for predicting postoperative forced expiratory volume.
  
  
  METHODS
  We assessed 48 patients with lung cancer who were candidates for lung resection. Forced spirometry, vibration response imaging, and ventilation/perfusion scan were performed in patients before surgery, and spirometry was performed after intervention.
  
  
  RESULTS
  We included 48 patients (43 men; mean age, 64 years) undergoing lung cancer surgery (32 lobectomies/16 pneumonectomies). On comparison of both techniques, for pneumonectomy, we found a concordance of 0.84 (95% confidence interval, 0.76-0.92) and Bland-Altman limits of agreement of -0.33 to +0.45, with an average difference of 0.064. By comparing postoperative spirometry with vibration response imaging, we found a concordance of 0.66 (95% confidence interval, 0.38-0.93) and Bland-Altman limits of agreement of -0.60 to +0.33, with an average difference of -0.13.
  
  
  CONCLUSIONS
  The 2 techniques presented good concordance values. Vibration response imaging shows non-negligible confidence intervals. Vibration response imaging may be useful in preoperative algorithms in patients before lung cancer surgery.
authors.affiliation: Department of Pulmonology, Cruces University Hospital, Basque Country, Spain. Electronic address: nuria.marinamalanda@osakidetza.net.
authors.forename: Nuria
authors.initials: N
authors.lastname: Marina
authors.affiliation: Department of Pulmonology, San Carlos Hospital, Madrid, Spain; Complutense University, Madrid, Spain.
authors.forename: Gema
authors.initials: G
authors.lastname: Rodriguez-Trigo
authors.affiliation: Department of Thoracic Surgery, Cruces University Hospital, Basque Country, Spain.
authors.forename: Unai
authors.initials: U
authors.lastname: Jimenez
authors.affiliation: Department of Pulmonology, San Carlos Hospital, Madrid, Spain.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Morales
authors.affiliation: Department of Pulmonology, Cruces University Hospital, Basque Country, Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: López de Santa María
authors.affiliation: Epidemiology Department, Cruces University Hospital, Basque Country, Spain.
authors.forename: José Ignacio
authors.initials: JI
authors.lastname: Pijoan
authors.affiliation: Department of Pulmonology, Cruces University Hospital, Basque Country, Spain; CibeRes and Basque Country University, Basque Country, Spain.
authors.forename: Juan B
authors.initials: JB
authors.lastname: Gáldiz
mesh_terms: D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D055420:Perfusion Imaging; D011013:Pneumonectomy; D011237:Predictive Value of Tests; D011446:Prospective Studies; D015203:Reproducibility of Results; D013147:Spirometry; D016896:Treatment Outcome; D014732:Vibration
keywords: 10; CI; CT; DLCO; FEV1; V/Q; VRI; computed tomography; confidence interval; diffusing capacity of the lung for carbon monoxide; forced expiratory volume in 1 second; ppoFEV1; predicted postoperative forced expiratory volume in 1 second; ventilation/perfusion scintigraphy; vibration response imaging