title: Hemimegalencephaly: A rare cause of hemihypoperfusion on 99m technetium-ethyl cysteinate dimer brain perfusion single-photon emission computed tomography.
abstract: Hemimegalencephaly is a rare congenital neuronal migration disorder that can presents with the equally rare finding of hemihypoperfusion on brain perfusion single-photon emission computed tomography (SPECT). It is an extremely rare cause of intractable epilepsy. Technetium-99m ethyl cysteinate dimer (ECD) brain perfusion SPECT is useful in excluding other foci of hypoperfusion in the contralateral since hemispherectomy has been suggested to be the treatment of choice. Furthermore, hemimegalencephaly may present with hyper as well as hypoperfusion on ECD SPECT. We present the case of an 11-year-old male child with intractable seizures who showed hemihypoperfusion in the hemimegalecephalic hemisphere.
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Nishikant A
authors.initials: NA
authors.lastname: Damle
authors.forename: Abhinav
authors.initials: A
authors.lastname: Singhal
authors.forename: Anirban
authors.initials: A
authors.lastname: Mukherjee
authors.forename: Manas Kumar
authors.initials: MK
authors.lastname: Sahoo
authors.forename: Madhavi
authors.initials: M
authors.lastname: Tripathi
authors.forename: Chandrasekhar
authors.initials: C
authors.lastname: Bal
keywords: 99m technetium-ethyl cysteinate dimer brain single-photon emission computed tomography; hemihypoperfusion; hemimegalencephaly