title: The EuroNet paediatric hodgkin network - modern imaging data management for real time central review in multicentre trials.
abstract: Since 2007, children and adolescents with Hodgkin lymphomas are treated in the Europe-wide EuroNet-PHL trials. A real time central review process for stratification of the patients enhances quality control and efficient therapy management. This process includes reading of all cross-sectional-images. Since reference evaluation is time critical, a fast, easy to handle and safe data transfer is important. In addition, immediate and constant access to all the data has to be guaranteed in case of queries and for regulatory reasons. To meet the mentioned requirements the EuroNet Paediatric Hodgkin Data Network (funded by the European Union - Project Number: 2007108) was established between 2008 and 2011. A respective tailored data protection plan was formulated. The aim of this article is to describe the networks' mode of operation and the advantages for multi-centre trials that include centralized image review.
authors.affiliation: Department of Nuclear Medicine, University Hospital of Leipzig, Germany.
authors.forename: L
authors.initials: L
authors.lastname: Kurch
authors.forename: C
authors.initials: C
authors.lastname: Mauz-Körholz
authors.forename: S
authors.initials: S
authors.lastname: Bertling
authors.forename: M
authors.initials: M
authors.lastname: Wallinder
authors.forename: M
authors.initials: M
authors.lastname: Kaminska
authors.forename: D
authors.initials: D
authors.lastname: Marwede
authors.forename: L
authors.initials: L
authors.lastname: Tchavdarova
authors.forename: T W
authors.initials: TW
authors.lastname: Georgi
authors.forename: A
authors.initials: A
authors.lastname: Elsner
authors.forename: A
authors.initials: A
authors.lastname: Barthel
authors.forename: D
authors.initials: D
authors.lastname: Stoevesandt
authors.forename: D
authors.initials: D
authors.lastname: Hasenclever
authors.forename: B
authors.initials: B
authors.lastname: Sattler
authors.forename: O
authors.initials: O
authors.lastname: Sabri
authors.forename: D
authors.initials: D
authors.lastname: Körholz
authors.forename: R
authors.initials: R
authors.lastname: Kluge
mesh_terms: D000293:Adolescent; D002648:Child; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data*; D003195:Computer Communication Networks / Q000458:organization & administration*; D016494:Computer Security; D003625:Data Collection; D003628:Database Management Systems / Q000458:organization & administration*; D003952:Diagnostic Imaging; D005060:Europe; D005062:European Union; D006689:Hodgkin Disease / Q000628:therapy*; D006801:Humans; D015337:Multicenter Studies as Topic / Q000706:statistics & numerical data*; D011786:Quality Control; D011873:Radiology Information Systems / Q000458:organization & administration*