title: Churg-Strauss angiitis.
abstract: Churg-Strauss angiitis is a rare vasculitic disorder affecting small- and medium-sized blood vessels. It is clinically characterized by the presence of a wide spectrum of multisystem organ involvement, with allergic rhinitis, asthma and peripheral blood eosinophilia as the most typical manifestations. The authors describe 2 cases of Churg-Strauss angiitis from an urban community of Southern Louisiana, exhibiting an atypical presentation with myocardial ischemia and cerebrovascular complications. Epidemiology, pathophysiology and clinical overview are presented. The therapeutic management is also discussed.
authors.affiliation: Department of Internal Medicine (NN) and Respiratory Institute (TN), Cleveland Clinic Foundation, Cleveland, Ohio; and Departments of Rheumatology (LRE) and Medicine (LRE), Section of Clinical Immunology (SD), Allergy & Rheumatology, Department of Medicine, Tulane Medical Center, New Orleans, Louisiana.
authors.forename: Neha
authors.initials: N
authors.lastname: Narula
authors.forename: Tathagat
authors.initials: T
authors.lastname: Narula
authors.forename: Stephen
authors.initials: S
authors.lastname: Derbes
authors.forename: Luis R
authors.initials: LR
authors.lastname: Espinoza
mesh_terms: D001249:Asthma / Q000188:drug therapy; D001921:Brain / Q000473:pathology*; D002545:Brain Ischemia / Q000175:diagnosis / Q000209:etiology*; D015267:Churg-Strauss Syndrome / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D020024:Leukotriene Antagonists / Q000009:adverse effects*; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000209:etiology*; D010523:Peripheral Nervous System Diseases / Q000209:etiology*; D014057:Tomography, X-Ray Computed
chemical_list: D020024:Leukotriene Antagonists