title: [Kampo medicine for the treatment of adverse effects caused by anticancer drugs].
abstract: In contrast to conventional single-target drugs, multicomponent Kampo medicines are designed to achieve therapeutic effects through multiple drug targets. This article discusses recent advances in mechanistic studies and the clinical effects of eight representative Kampo formulations (Rikkunshito, Hangeshashinto, Daikenchuto, Goshajinkigan, Yokukansan, and the tonics Hochuekkito, Juzentaihoto, and Ninjinyoeito) for the treatment of adverse effects caused by anticancer drugs such as anorexia, oral mucositis, diarrhea, neurotoxicity, abnormal behavior, malaise, weakness, and thrombocytopenia, which Western pharmaceuticals fail to address adequately.
authors.affiliation: Advanced Surgery Center, Sapporo Higashi Tokushukai Hospital.
authors.forename: Toru
authors.initials: T
authors.lastname: Kono
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takeda
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Uezono
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D005894:Panax; D010936:Plant Extracts / Q000627:therapeutic use; D032106:Zanthoxylum; D030521:Zingiberaceae
chemical_list: D000970:Antineoplastic Agents; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; C524644:Yi-Gan San; C121414:dai-kenchu-to; C119642:gosha-jinki-gan; C088236:hange-shashinto; C084136:liu-jun-zi-tang