title: Antibacterial activity of Phyllantus emblica, Coriandrum sativum, Culinaris medic, Lawsonia alba and Cucumis sativus.
abstract: Present study deals with the demonstration of the antibacterial activity of very common medicinal plants of Pakistani origin i.e., Phyllantus emblica, Coriandrum sativum, Culinaris medic, Lawsonia alba and Cucumis sativus. The extracts were prepared in crude form by the use of hydro-alcoholic solution and were screened for antibacterial activity against various bacterial species by disk diffusion method. Assay was performed using clinical isolates of B. cereus, S. aureus, P. aeruginosa and E. coli. Crude extract of Phyllantus emblica fruit exhibited strong activity against standard cultures of all studied bacteria. Lawsonia alba showed good activity against standard cultures of all the used microorganisms. Coriandrum sativum was effective only against Bacillus cereus, while Cucumis sativus and Culinaris medic showed poor activity against Pseudomonas aeruginosa only. Hence, Phyllantus emblica exhibited strong antibacterial activity against a wide range of bacteria it means that Phyllantus emblica extract contains some compounds which have broad spectrum of bactericidal activity.
authors.affiliation: Department of Pharmaceutics, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan. khanalidawood@gmail.com
authors.forename: Dawood Ali
authors.initials: DA
authors.lastname: Khan
authors.forename: Fouzia
authors.initials: F
authors.lastname: Hassan
authors.forename: Hanif
authors.initials: H
authors.lastname: Ullah
authors.forename: Sabiha
authors.initials: S
authors.lastname: Karim
authors.forename: Abdul
authors.initials: A
authors.lastname: Baseer
authors.forename: Mobasher Ali
authors.initials: MA
authors.lastname: Abid
authors.forename: Muhammad
authors.initials: M
authors.lastname: Ubaidi
authors.forename: Shujaat Ali
authors.initials: SA
authors.lastname: Khan
authors.forename: Ghulam
authors.initials: G
authors.lastname: Murtaza
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D028526:Coriandrum / Q000737:chemistry; D028462:Cucumis / Q000737:chemistry; D031564:Lawsonia Plant / Q000737:chemistry; D027806:Lens Plant / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents