title: Useful indicators to interpret the cancer burden in Italy.
abstract: BACKGROUND
  In the last decades the demographics of most Western countries have undergone a deep transformation, which has caused a steady increase in degenerative chronic diseases and has made maintaining health and social support by the welfare system difficult. This paper aims to present a set of indicators pertaining to the health status of the Italian population and to the national economic and social systems, as an aid to a better interpretation of the cancer burden impact and of its future tendencies.
  
  
  METHODS
  All indicators were derived from the ISTAT Health for All database. They were presented by region or macro area, globally or by gender, considering the most recent regional distribution and their time trends. The following features of the Italian population were chosen: percent of people aged over 65 years; life expectancy at birth; birth rate; crude and age-standardized overall mortality rates; dependency ratio; percent of single persons; percent of people with no more than a junior high school diploma; percent of people attaining at least the short first university degree; percent of people employed in the service and tertiary sectors; unemployment rate; incidence of poverty; total health expenditure (THE) as an absolute value and as percent of GDP; percent of public THE; percent of out-of-pocket THE of households; percent of smokers; proportion of overweight and obese people aged ≥18 years.
  
  
  RESULTS
  Italy presented an unbalanced demographic situation with an increasingly old population, a decreasing middle-aged age group, a low birth rate, high crude overall mortality rates, and decreasing standardized overall mortality rates. The Italian population is characterized by a constant increase in the dependency ratio and in the percentage of people living alone, together with increasing expenses for health care, both at the public and households levels. Smoking has reduced its impact in men but not yet in women. The increasing proportion of overweight and obese people may explain the convergence in time of the mortality rates of the different Italian macro areas.
  
  
  CONCLUSIONS
  The Italian situation seems to be not well fitted to face the expected growing cancer burden. Along with the aging of the population, the corresponding lowering of the national GDP due to the persisting global economic crisis will lead the public sector and families to reduce health expenditure, while the number of people affected by cancer is bound to increase. Moreover, the social support provided by family members and the advantages of the Mediterranean dietary habits are declining. The strategies for facing the challenging evolution of the future should focus on successful primary prevention and a wider application of evidence-based medicine to optimize the choice of diagnostic and therapeutic procedures offered to citizens.
authors.forename: Marina
authors.initials: M
authors.lastname: Vercelli
authors.forename: Alberto
authors.initials: A
authors.lastname: Quaglia
authors.forename: Roberto
authors.initials: R
authors.lastname: Lillini
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease / Q000453:epidemiology; D017281:Cost of Illness; D016208:Databases, Factual; D004522:Educational Status; D004651:Employment; D005260:Female; D059066:Gross Domestic Product; D005102:Health Expenditures; D006304:Health Status; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008017:Life Expectancy / Q000639:trends*; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009026:Mortality / Q000639:trends; D009369:Neoplasms / Q000453:epidemiology* / Q000401:mortality; D009765:Obesity / Q000453:epidemiology; D011157:Population Dynamics / Q000639:trends*; D015995:Prevalence; D017150:Public Sector; D012944:Social Support; D015996:Survival Rate / Q000639:trends