title: Silver ion promoted, Pd(II)-catalyzed arylation of arenes with a free amine as directing group in aqueous medium.
abstract: Palladium(II)-catalyzed arylation of arenes with aryl boronic acids and a free amine as directing group in aqueous medium has been developed. High reactivity and chemoselectivity for the formation of carbon-carbon bonds were achieved by the use of soluble silver salts. The addition of water is crucial to improve the arylation yield.
authors.affiliation: ZJU-NHU United R&D Center, Department of Chemistry, Zhejiang University, Hangzhou 310027 (P. R. China), Fax: (+86) 571-87953244.
authors.forename: Zunjun
authors.initials: Z
authors.lastname: Liang
authors.forename: Jinzhong
authors.initials: J
authors.lastname: Yao
authors.forename: Kai
authors.initials: K
authors.lastname: Wang
authors.forename: Haoran
authors.initials: H
authors.lastname: Li
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Zhang
keywords: CH activation; amines; homogeneous catalysis; palladium; silver