title: The effects of maggot secretions on the inflammatory cytokines in serum of traumatic rats.
abstract: The objective of this study was to analyse the changes of inflammatory cytokines level in traumatic rat serum after maggot secretions intervention. Acute traumatic rats were randomly divided into three groups that included maggot secretions group, negative group, and the control group. TNF-α, IL-6, SOD, LPO levels were measured by radioimmunoassay. The experimental results showed that TNF-α, IL-6, and SOD levels in the model group were significantly increased; LPO level was decreased and showed significant differences. Thus, the content of inflammatory cytokines in acute skin wounds could be reduced by maggot secretions, which play a role in enhancing wound healing.
authors.affiliation: Central Laboratory, The Luhe Teaching Hospital of the Capital Medical University.
authors.forename: Xiaorong
authors.initials: X
authors.lastname: Li
authors.forename: Ning
authors.initials: N
authors.lastname: Liu
authors.forename: Xiaoyong
authors.initials: X
authors.lastname: Xia
authors.forename: Shaochun
authors.initials: S
authors.lastname: Zhang
authors.forename: Junlong
authors.initials: J
authors.lastname: Bai
authors.forename: Jiangning
authors.initials: J
authors.lastname: Wang
mesh_terms: D000818:Animals; D001688:Biological Products / Q000494:pharmacology; D012634:Bodily Secretions; D016207:Cytokines / Q000097:blood*; D004175:Diptera; D005260:Female; D018836:Inflammation Mediators / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood; D007814:Larva; D008297:Male; D010545:Peroxides / Q000097:blood; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000293:injuries*; D013482:Superoxide Dismutase / Q000097:blood; D014409:Tumor Necrosis Factor-alpha / Q000097:blood; D014945:Wound Healing / Q000187:drug effects*; D014951:Wounds, Stab / Q000097:blood*
chemical_list: D001688:Biological Products; D016207:Cytokines; D018836:Inflammation Mediators; D015850:Interleukin-6; D010545:Peroxides; D014409:Tumor Necrosis Factor-alpha; D013482:Superoxide Dismutase
keywords: Maggot secretions; inflammatory cytokines; serum; wounds