title: Current progress and challenges in the search for autism biomarkers.
abstract: Autism spectrum disorders (ASD) encompass a range of neurodevelopmental conditions that are clinically and etiologically very heterogeneous. ASD is currently diagnosed entirely on behavioral criteria, but intensive research efforts are focused on identifying biological markers for disease risk and early diagnosis. Here, we discuss recent progress toward identifying biological markers for ASD and highlight specific challenges as well as ethical aspects of translating ASD biomarker research into the clinic.
authors.affiliation: School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, Sydney, NSW 2052, Australia.
authors.forename: Irina
authors.initials: I
authors.lastname: Voineagu
authors.forename: Hee Jeong
authors.initials: HJ
authors.lastname: Yoo
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology / Q000503:physiopathology; D002508:Cephalometry; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D005819:Genetic Markers; D020022:Genetic Predisposition to Disease; D006801:Humans; D008928:Mitochondria / Q000378:metabolism; D018384:Oxidative Stress; D012701:Serotonin / Q000378:metabolism; D059467:Transcriptome
chemical_list: D005819:Genetic Markers; D012701:Serotonin