title: Implant-retained dental rehabilitation in head and neck cancer patients: an assessment of success and failure.
abstract: BACKGROUND
  This study aimed to evaluate the rate of osseointegration (ROI) and overall success rate (OSR) of implants placed in native and grafted jaws with or without radiotherapy at a 5-year follow-up in Indian head and neck cancer patients.
  
  
  METHODS
  Thirty head and neck cancer patients from various socioeconomic strata were accrued. Eighty-five implants were inserted in 17 native and 13 grafted jaws. Nineteen patients received radiation therapy. A 5-year follow-up ROI and OSR of implants were reported.
  
  
  RESULTS
  The 5-year ROI and OSR were 88% and 77%, respectively. ROI was 93% for grafted, 85% for native, 83% for irradiated, and 100% for nonirradiated jaws. OSR was 73% for grafted, 80% for native, 71% for irradiated, and 89% for nonirradiated jaws. Patients from higher socioeconomic strata had higher OSR (92%) as compared with those belonging to lower socioeconomic strata (65%).
  
  
  CONCLUSIONS
  The failure rate observed in this study was 24% for implants placed in head and neck cancer patients at a 5-year follow-up.
authors.affiliation: *Head and Professor, Department of Dental and Prosthetic Surgery, Tata Memorial Hospital, Mumbai, India. †Assistant Professor, Department of Dental and Prosthetic Surgery, Tata Memorial Hospital, Mumbai, India. ‡Head, Department of Cancer Surgery, Tata Memorial Hospital, Mumbai, India. §Assistant Professor, Department of Cancer Surgery, Tata Memorial Hospital, India. ‖Fellow, Department of Dental and Prosthetic Surgery, Tata Memorial Hospital, Mumbai, India.
authors.forename: Kanchan P
authors.initials: KP
authors.lastname: Dholam
authors.forename: Hrishikesh A
authors.initials: HA
authors.lastname: Pusalkar
authors.forename: Prabha S
authors.initials: PS
authors.lastname: Yadav
authors.forename: Ghazwan A
authors.initials: GA
authors.lastname: Quazi
authors.forename: Priyanka P
authors.initials: PP
authors.lastname: Somani
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003758:Dental Implantation, Endosseous; D017268:Dental Prosthesis Retention / Q000706:statistics & numerical data*; D019232:Dental Restoration Failure / Q000706:statistics & numerical data; D005260:Female; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000534:rehabilitation / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016348:Osseointegration; D055815:Young Adult