title: Non-natural phenolic amino acids Synthesis and application in peptide chemistry.
abstract: Several non-natural phenolic amino acids have been synthesized.t-Butylated tyrosine and thyroxine derivatives, on one-electron oxidation, give persistent radicals which can be used as positional and/or spin labels for amino acids. Two-electron oxidation ofN-protected tyrosines leads to spirolactones, useful active esters for peptide coupling.
authors.affiliation: Institute of Organic Chemistry, University of Tübingen, Auf der Morgenstelle 18, D-72076, Tübingen, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Hutinec
authors.forename: A
authors.initials: A
authors.lastname: Ziogas
authors.forename: A
authors.initials: A
authors.lastname: Rieker