title: A novel nonenzymatic sensor based on CuO nanoneedle/graphene/carbon nanofiber modified electrode for probing glucose in saliva.
abstract: Here, we report on a novel nonenzymatic amperometric glucose sensor based on CuO nanoneedle/graphene/carbon nanofiber modified electrode. The results of the scanning electron microscopy indicate that electronic network was formed through their direct binding with the graphene/carbon nanofiber, which leads to larger active surface areas and faster electron transfer for the glucose sensor. High electrocatalytic activity toward the oxidation of glucose was observed with a rapid response (<2 s), a low detection limit (0.1 µM), a wide and useful linear range (1-5.3 mM) as well as good stability and repeatability. Moreover, the common interfering species, such as ascorbic acid, uric acid, dopamine and so forth did not cause obvious interference. The sensor can also be used for quantification of glucose concentration in real saliva samples. Therefore, this work has demonstrated a simple and effective sensing platform for nonenzymatic detection of glucose.
authors.affiliation: Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, PR China.
authors.forename: Daixin
authors.initials: D
authors.lastname: Ye
authors.forename: Guohai
authors.initials: G
authors.lastname: Liang
authors.forename: Huixiang
authors.initials: H
authors.lastname: Li
authors.forename: Juan
authors.initials: J
authors.lastname: Luo
authors.forename: Song
authors.initials: S
authors.lastname: Zhang
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.forename: Jilie
authors.initials: J
authors.lastname: Kong
mesh_terms: D003300:Copper / Q000737:chemistry*; D055664:Electrochemical Techniques; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D046529:Microscopy, Electron, Transmission; D057139:Nanofibers / Q000737:chemistry* / Q000648:ultrastructure; D010084:Oxidation-Reduction; D012463:Saliva / Q000737:chemistry*
chemical_list: D006108:Graphite; D003300:Copper; D005947:Glucose; C030973:cupric oxide
keywords: Carbon fiber; CuO nanoneedle; Glucose; Graphene