title: Mediators of 12-month outcomes of two Internet interventions for youth with type 1 diabetes.
abstract: OBJECTIVE
  To determine mediators of 12-month outcomes of Internet interventions for youth with type 1 diabetes transitioning to adolescence.
  
  
  METHODS
  In this multisite clinical trial, 320 youth were randomized to one of two Internet-based interventions: Coping skills (TEENCOPE™) or diabetes education (Managing Diabetes). Mediators of the interventions' effects on glycosylated hemoglobin and quality of life were examined. Data were collected at baseline and at 3, 6, and 12 months.
  
  
  RESULTS
  Self-efficacy mediated treatment effects on quality of life in both interventions. For TEENCOPE™, stress reactivity, primary control coping, and secondary control coping mediated treatment effects, whereas for Managing Diabetes, social acceptance mediated treatment effects. There were no significant effects of either intervention on glycosylated hemoglobin.
  
  
  CONCLUSIONS
  2 Internet interventions for youth with type 1 diabetes resulted in improved quality of life by different mechanisms, suggesting components of both diabetes education and coping skills may help to achieve better outcomes in youth with type 1 diabetes.
authors.affiliation: Vanderbilt University, Department of Pediatrics, 2200 Children's Way, Nashville, TN 37232, USA. sarah.jaser@vanderbilt.edu.
authors.forename: Sarah S
authors.initials: SS
authors.lastname: Jaser
authors.forename: Robin
authors.initials: R
authors.lastname: Whittemore
authors.forename: Ariana
authors.initials: A
authors.lastname: Chao
authors.forename: Sangchoon
authors.initials: S
authors.lastname: Jeon
authors.forename: Melissa S
authors.initials: MS
authors.lastname: Faulkner
authors.forename: Margaret
authors.initials: M
authors.lastname: Grey
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000523:psychology* / Q000628:therapy; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D020407:Internet; D008297:Male; D008960:Models, Psychological; D010353:Patient Education as Topic; D011788:Quality of Life; D012648:Self Care; D020377:Self Efficacy
chemical_list: D006442:Glycated Hemoglobin
keywords: coping skills; intervention studies; quality of life; type 1 diabetes mellitus