title: In vivo effectiveness of enamel sealants around orthodontic brackets.
abstract: OBJECTIVE
  In this randomized study, the caries-protective effect on vestibular enamel of two fluoride-containing sealants (Protecto® and Light Bond®) during multibracket treatment was investigated.
  
  
  METHODS
  In all, 40 orthodontic patients about to receive a multibracket appliance with the brackets bonded to the vestibular tooth surfaces were randomly included in this study. Each one was randomly assigned to one of four groups. A crossover design was selected in which a sealed quadrant was contralateral to an unsealed quadrant, then choosing the reverse configuration in the opposite jaw. Two sealants were, thus, tested on vestibular enamel on left and right anterior teeth and premolars in both jaws of each patient over 6 months of multibracket treatment. A DIAGNOdent® pen measuring laser fluorescence was used to analyze the relevant enamel surfaces both at baseline and after 6 months.
  
  
  RESULTS
  Neither the incidence nor the characteristics of the demineralization we observed during the study differed between the 4 groups.
  
  
  CONCLUSIONS
  Single application of smooth-surface sealants did not protect enamel around brackets from incipient carious lesions during the first 6 months of multibracket treatment.
authors.affiliation: Department of Orthodontics, Center of Dentistry, Oral Medicine, and Maxillofacial Surgery, Eberhard-Karls University Tübingen, Osianderstr. 2-8, 72076, Tübingen, Germany.
authors.forename: T E
authors.initials: TE
authors.lastname: Bechtold
authors.forename: A
authors.initials: A
authors.lastname: Sobiegalla
authors.forename: M
authors.initials: M
authors.lastname: Markovic
authors.forename: M
authors.initials: M
authors.lastname: Berneburg
authors.forename: G R
authors.initials: GR
authors.lastname: Göz
mesh_terms: D000293:Adolescent; D002327:Cariostatic Agents / Q000627:therapeutic use; D001840:Dental Bonding / Q000009:adverse effects*; D003743:Dental Enamel / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008689:Methacrylates / Q000627:therapeutic use*; D016910:Orthodontic Brackets / Q000009:adverse effects*; D010895:Pit and Fissure Sealants / Q000627:therapeutic use*; D017640:Silicates / Q000627:therapeutic use*; D017001:Tooth Demineralization / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D002327:Cariostatic Agents; D008689:Methacrylates; D010895:Pit and Fissure Sealants; D017640:Silicates; C030887:Protecto