title: Chronic lymphocytic leukemia developing in a case of chronic myelogenous leukemia--accelerated phase: a rare case with review of the literature.
abstract: Chronic myelogenous leukemia (CML) and chronic lymphocytic leukemia (CLL) are two different and common hematological neoplasms. Their coexistence is rare, especially CLL developing in a patient of CML. Till date, only a few cases are reported and all had chronic myeloid leukemia - chronic phase earlier. We report the first case of CLL developing in a patient initially diagnosed in an accelerated phase of chronic myeloid leukemia. The clonality of both CML and CLL was proven by cytogenetic, molecular and flow cytometric studies.
authors.affiliation: Department of Hematology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
authors.forename: Narender
authors.initials: N
authors.lastname: Kumar
authors.forename: Jasmina
authors.initials: J
authors.lastname: Ahluwalia
authors.forename: Pankaj
authors.initials: P
authors.lastname: Malhotra
authors.forename: Man Updesh Singh
authors.initials: MU
authors.lastname: Sachdeva
mesh_terms: D001773:Blood Cells; D001853:Bone Marrow / Q000473:pathology; D003582:Cytogenetics; D003584:Cytological Techniques; D005260:Female; D005434:Flow Cytometry; D006651:Histocytochemistry; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis* / Q000473:pathology*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications*; D008853:Microscopy; D008875:Middle Aged