title: Association between shiftwork and glomerular filtration rate in police officers.
abstract: OBJECTIVE
  To investigate associations between shiftwork and glomerular filtration rate among white/Hispanic (n = 273) and African American (n = 81) police officers.
  
  
  METHODS
  Analysis of variance/analysis of variance was utilized to compare mean values of estimated glomerular filtration rate (eGFR) across shiftwork categories.
  
  
  RESULTS
  Shiftwork was significantly associated with eGFR among white/Hispanic officers only: day (88.6 ± 2.8), afternoon (90.6 ± 2.9), and night shift (83.1 ± 3.1 mL/min/1.73 m); afternoon versus night, P = 0.007. Percentage of hours worked on the night shift was inversely associated with mean levels of eGFR, trend P = 0.001. Body mass index modified the association between shiftwork and eGFR (interaction P = 0.038). Among officers with body mass index 25 kg/m or higher, those who worked the night shift had the lowest mean eGFR (afternoon vs night, P = 0.012; day vs night, P = 0.029).
  
  
  CONCLUSIONS
  Night-shift work was associated with decreased kidney function among white/Hispanic officers. Longitudinal studies are warranted among all races.
authors.affiliation: From the Biostatistics and Epidemiology Branch (Dr Charles, Ms Gu, Dr Fekedulegn, Dr Andrew, and Dr Burchfiel), Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WVa; and Department of Social and Preventive Medicine (Dr Violanti), School of Public Health and Health Professions, State University of New York at Buffalo.
authors.forename: Luenda E
authors.initials: LE
authors.lastname: Charles
authors.forename: Ja K
authors.initials: JK
authors.lastname: Gu
authors.forename: Desta
authors.initials: D
authors.lastname: Fekedulegn
authors.forename: Michael E
authors.initials: ME
authors.lastname: Andrew
authors.forename: John M
authors.initials: JM
authors.lastname: Violanti
authors.forename: Cecil M
authors.initials: CM
authors.lastname: Burchfiel
mesh_terms: D000328:Adult; D001741:Black or African American; D015992:Body Mass Index; D005260:Female; D005919:Glomerular Filtration Rate; D006630:Hispanic or Latino; D006801:Humans; D035846:Law Enforcement; D008297:Male; D008875:Middle Aged; D016495:Police; D011795:Surveys and Questionnaires; D013997:Time Factors; D044465:White People; D014940:Work Schedule Tolerance / Q000502:physiology*