title: Myeloma after local external beam radiotherapy jet: Is it a new entity?
abstract: Multiple myeloma, also known as Kahler's disease, is a cancer of plasma cells that abnormally accumulate in bone marrow. Radiation therapy may be indicated in multiple myeloma to relieve pain, alleviate spinal cord compression or reduce tumor mass. We report the case of a patient presenting a multiple myeloma, treated with radiation therapy for a spinal cord compression, who developed, eleven months later, an in-field subcutaneous relapse. We called this phenomenon myeloma appearance after local external beam radiotherapy jet (MAALEJ). A review of literature was performed trying to explain this uncommon relapse feature.
authors.affiliation: Radiation oncology department, Salah-Azaiez Institute, Bab-Saadoun, 1006 Tunis, Tunisia; Medicine university of Tunis, Tunis-El-Manar University, 1068 El-Manar 2, Tunisia.
authors.forename: M
authors.initials: M
authors.lastname: Maalej
authors.forename: A
authors.initials: A
authors.lastname: Belaïd
authors.forename: M
authors.initials: M
authors.lastname: Laabidi
authors.forename: N
authors.initials: N
authors.lastname: Ben Romdhane
authors.forename: L
authors.initials: L
authors.lastname: Kochbati
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000532:radiotherapy*; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000532:radiotherapy; D012878:Skin Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D013117:Spinal Cord Compression / Q000209:etiology / Q000628:therapy
keywords: Champ; Cutaneous; Cutané; Field; Multiple myeloma; Myélome multiple; Radiation therapy; Radiothérapie; Relapse; Récidive