title: No link between breast cancer and meningioma: results from a large monoinstitutional retrospective analysis.
abstract: BACKGROUND
  The etiology of meningioma is largely unknown, although breast cancer has been suggested to play a role.
  
  
  METHODS
  A monoinstitutional, retrospective analysis was performed at European Institute of Oncology on 12,330 patients with breast cancer. The cumulative incidence of meningioma was estimated using the Kaplan-Meier method and the log-rank test was used to assess differences between groups.
  
  
  RESULTS
  In total, 33 patients with meningioma were identified from a study population of 12,330, with a 10-year cumulative incidence of meningioma of 0.37%. We did not find a significantly increased risk of meningioma among patients with breast cancer or an association between the hormonal receptor status and the risk of meningioma (P = 0.65).
  
  
  CONCLUSIONS
  Our results do not support a role of breast cancer or endocrine treatments in meningioma development.
  
  
  CONCLUSIONS
  This analysis adds new information on a debated topic.
authors.affiliation: Authors' Affiliations: Breast Cancer Program, Division of Early Drug Development, Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan; and Department of Advanced Biomedical Sciences, Operative Unit of General Surgery and Transplants, University Naples Federico II, Napoli, Italy.
authors.forename: Carmen
authors.initials: C
authors.lastname: Criscitiello
authors.forename: Davide
authors.initials: D
authors.lastname: Disalvatore
authors.forename: Michele
authors.initials: M
authors.lastname: Santangelo
authors.forename: Nicole
authors.initials: N
authors.lastname: Rotmensz
authors.forename: Barbara
authors.initials: B
authors.lastname: Bazolli
authors.forename: Patrick
authors.initials: P
authors.lastname: Maisonneuve
authors.forename: Aron
authors.initials: A
authors.lastname: Goldhirsch
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Curigliano
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008579:Meningioma / Q000453:epidemiology*; D008875:Middle Aged; D012042:Registries; D012189:Retrospective Studies