title: Exploring adenylylation and phosphocholination as post-translational modifications.
abstract: Editing the translations: Adenylylation and phosphocholination have recently been found as important post-translational modifications used by pathogenic bacteria during the infection process. This review discusses the combined use of chemical handles and specific antibodies for the identification of previously unknown substrates of these post-translational modifications in infected host cells.
authors.affiliation: Department of Physical Biochemistry, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund (Germany).
authors.forename: Matthias P
authors.initials: MP
authors.lastname: Müller
authors.forename: Michael F
authors.initials: MF
authors.lastname: Albers
authors.forename: Aymelt
authors.initials: A
authors.lastname: Itzen
authors.forename: Christian
authors.initials: C
authors.lastname: Hedberg
mesh_terms: D000241:Adenosine / Q000737:chemistry / Q000378:metabolism*; D000906:Antibodies / Q000276:immunology; D001419:Bacteria / Q000378:metabolism; D004798:Enzymes / Q000378:metabolism; D010455:Peptides / Q000032:analysis / Q000138:chemical synthesis; D010767:Phosphorylcholine / Q000737:chemistry / Q000378:metabolism*; D011499:Protein Processing, Post-Translational
chemical_list: D000906:Antibodies; D004798:Enzymes; D010455:Peptides; D010767:Phosphorylcholine; D000241:Adenosine
keywords: adenylylation; antibodies; bioorganic chemistry; mass spectrometry; phosphocholination; post-translational modifications