title: Epicardial fat thickness is independently associated with psoriasis.
abstract: BACKGROUND
  Several studies have showed an association between psoriasis and cardiovascular (CV) diseases and metabolic syndrome (MS). Assessment of CV risk in patients with psoriasis has become an important issue. Epicardial fat thickness (EFT) is an emerging cardiometabolic risk factor and has been shown to be related to atherosclerosis. EFT has not been studied in the context of psoriasis.
  
  
  OBJECTIVE
  To compare the EFT in psoriasis patients with that in control subjects.
  
  
  METHODS
  31 patients with psoriasis and 32 control subjects were included in this case-control study. EFT was evaluated by two-dimensional transthoracic echocardiography.
  
  
  RESULTS
  EFT was significantly higher in psoriasis patients compared to controls (p = 0.027). Multiple linear regression analysis showed that the association of EFT with psoriasis was independent of MS and age.
  
  
  CONCLUSIONS
  EFT, which has been suggested as a cardiometabolic risk factor in various diseases, is also independently associated with psoriasis.
authors.affiliation: Department of Cardiology, İzmir Katip Çelebi University Ataturk Training and Research Hospital, Izmir, Turkey.
authors.forename: Zehra Ilke
authors.initials: ZI
authors.lastname: Akyildiz
authors.forename: Sila
authors.initials: S
authors.lastname: Seremet
authors.forename: Volkan
authors.initials: V
authors.lastname: Emren
authors.forename: Sinan
authors.initials: S
authors.lastname: Ozcelik
authors.forename: Bilal
authors.initials: B
authors.lastname: Gediz
authors.forename: Ahmet
authors.initials: A
authors.lastname: Tastan
authors.forename: Cem
authors.initials: C
authors.lastname: Nazlı
mesh_terms: D050154:Adiposity; D000328:Adult; D000367:Age Factors; D015415:Biomarkers; D002318:Cardiovascular Diseases / Q000150:complications* / Q000503:physiopathology; D016022:Case-Control Studies; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000503:physiopathology; D008875:Middle Aged; D010496:Pericardium / Q000000981:diagnostic imaging*; D011565:Psoriasis / Q000150:complications* / Q000503:physiopathology; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D015415:Biomarkers