title: Cortical high-density counterstream architectures.
abstract: Small-world networks provide an appealing description of cortical architecture owing to their capacity for integration and segregation combined with an economy of connectivity. Previous reports of low-density interareal graphs and apparent small-world properties are challenged by data that reveal high-density cortical graphs in which economy of connections is achieved by weight heterogeneity and distance-weight correlations. These properties define a model that predicts many binary and weighted features of the cortical network including a core-periphery, a typical feature of self-organizing information processing systems. Feedback and feedforward pathways between areas exhibit a dual counterstream organization, and their integration into local circuits constrains cortical computation. Here, we propose a bow-tie representation of interareal architecture derived from the hierarchical laminar weights of pathways between the high-efficiency dense core and periphery.
authors.affiliation: Stem cell and Brain Research Institute, INSERM U846, 18 Avenue Doyen Lépine, 69500 Bron, France.|Université de Lyon, Université Lyon I, 69003 Lyon, France.|Yale University, Department of Neurobiology, New Haven, CT 06520, USA.
authors.forename: Nikola T
authors.initials: NT
authors.lastname: Markov
authors.affiliation: Faculty of Physics, Babeş-Bolyai University, Cluj-Napoca, 400084 Romania.
authors.forename: Mária
authors.initials: M
authors.lastname: Ercsey-Ravasz
authors.affiliation: Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, MO 63110-1093, USA.
authors.forename: David C
authors.initials: DC
authors.lastname: Van Essen
authors.affiliation: Stem cell and Brain Research Institute, INSERM U846, 18 Avenue Doyen Lépine, 69500 Bron, France.|Université de Lyon, Université Lyon I, 69003 Lyon, France.
authors.forename: Kenneth
authors.initials: K
authors.lastname: Knoblauch
authors.affiliation: Department of Physics and Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, IN 46556, USA.|Max Planck Institute for the Physics of Complex Systems, 01187 Dresden, Germany.
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Toroczkai
authors.affiliation: Stem cell and Brain Research Institute, INSERM U846, 18 Avenue Doyen Lépine, 69500 Bron, France.|Université de Lyon, Université Lyon I, 69003 Lyon, France.
authors.forename: Henry
authors.initials: H
authors.lastname: Kennedy
mesh_terms: D002540:Cerebral Cortex / Q000502:physiology* / Q000648:ultrastructure*; D006801:Humans; D008606:Mental Processes / Q000502:physiology; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology* / Q000648:ultrastructure*