title: [Cytomegalovirus jejunitis diagnosed with single-balloon enteroscopy].
abstract: Cytomegalovirus (CMV) infections are usually diagnosed in immunocompromised patients. A 74-year-old male without any significant medical history visited our center because of abdominal pain and diarrhea which began about a month ago. Abdominal computed tomography revealed segmental enhanced bowel wall thickening on jejunum and single-balloon enteroscopy showed multiple geographic shaped ulcerations covered with exudates on proximal jejunum. Biopsy samples taken during endoscopic examination demonstrated necrotic fibrinopurulent tissue debris and benign ulcer. Nested-PCR analysis of CMV DNA from jejunal tissue was positive. The patient was finally diagnosed with CMV jejunitis and was treated by intravenous ganciclovir for 14 days after which, abdominal pain and diarrhea improved. Our case shows that CMV jejunitis can occur in an immunocompetent adult as multiple jejunal ulcers which can be diagnosed using a single-balloon enteroscope.
authors.affiliation: Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Eung Jun
authors.initials: EJ
authors.lastname: Lee
authors.forename: Hyun Sung
authors.initials: HS
authors.lastname: Yoon
authors.forename: Cho I
authors.initials: CI
authors.lastname: Lee
authors.forename: Yun Serk
authors.initials: YS
authors.lastname: Lee
authors.forename: Sung Noh
authors.initials: SN
authors.lastname: Hong
authors.forename: Sun-Young
authors.initials: SY
authors.lastname: Lee
authors.forename: In-Kyung
authors.initials: IK
authors.lastname: Sung
authors.forename: Chan Sup
authors.initials: CS
authors.lastname: Shim
mesh_terms: D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use; D003587:Cytomegalovirus / Q000235:genetics / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D004279:DNA, Viral / Q000032:analysis; D016099:Endoscopy, Gastrointestinal; D004751:Enteritis / Q000175:diagnosis* / Q000209:etiology / Q000821:virology; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D007275:Injections, Intravenous; D007579:Jejunal Diseases / Q000175:diagnosis* / Q000209:etiology / Q000821:virology; D008297:Male; D016133:Polymerase Chain Reaction; D014057:Tomography, X-Ray Computed
chemical_list: D000998:Antiviral Agents; D004279:DNA, Viral; D015774:Ganciclovir