title: Kyphoplasty increases vertebral height, decreases both pain score and opiate requirements while improving functional status.
abstract: Vertebral compression fractures can result from advanced osteoporosis, or less commonly from metastatic or traumatic insults to the vertebral column, and result in disabling pain and decreased functional capacity. Various vertebral augmentation options including kyphoplasty aim at preventing the sequelae of pain and immobility that can develop as the result of the vertebral fractures. The mechanism for pain relief following kyphoplasty is not entirely understood, and the restoration of a portion of the lost vertebral height is a subject of debate. We retrospectively reviewed radiographic imaging, pain relief, analgesic intake and functional outcomes in 67 consecutive patients who underwent single- or multilevel kyphoplasty with the primary goal of quantifying the restoration of lost vertebral height. We observed a mean of 45% of the lost vertebral height restored postprocedurally. Secondarily, kyphoplasty was associated with significant decreases in pain scores, daily morphine consumption and improvement in patient-reported functional measures.
authors.affiliation: Department of Pain Management, Cleveland Clinic, Cleveland, Ohio, U.S.A.
authors.forename: Reda
authors.initials: R
authors.lastname: Tolba
authors.forename: Robert B
authors.initials: RB
authors.lastname: Bolash
authors.forename: Joshua
authors.initials: J
authors.lastname: Shroll
authors.forename: Shrif
authors.initials: S
authors.lastname: Costandi
authors.forename: Jarrod E
authors.initials: JE
authors.lastname: Dalton
authors.forename: Chirag
authors.initials: C
authors.lastname: Sanghvi
authors.forename: Nagy
authors.initials: N
authors.lastname: Mekhail
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D005260:Female; D050815:Fractures, Compression / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D058498:Kyphoplasty; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D010147:Pain Measurement; D011859:Radiography; D012189:Retrospective Studies; D016103:Spinal Fractures / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D013131:Spine / Q000000981:diagnostic imaging / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D000701:Analgesics, Opioid
keywords: kyphoplasty; kyphosis; osteoporosis; percutaneous vertebral augmentation; vertebral compression fracture; vertebral height restoration