title: Hypersensitivity to Etoposide in case of metastatic gestational choriocarcinoma.
abstract: Etoposide is commonly used in the treatment of a variety of neoplasms. Hypersensitivity reactions to etoposide are infrequently reported and include hypotension, hypertension, flushing, diaphoresis, chest discomfort, dyspnea, bronchospasm and loss of consciousness. We report the case of a 39-year-old woman who experienced acute bronchospasm, tachycardia, hypoxia and hypotension. The symptoms resolved within an hour after administration of intravenous fluids, methylprednisolone, diphenhydramine and oxygen. Subsequently, the patient was given etoposide phosphate without incident.
authors.affiliation: Department of Pulmonology, Clinical Hospital Center Zemun-Belgrade, Serbia, Germany.
authors.forename: Biljana
authors.initials: B
authors.lastname: Lazović
authors.forename: Vera
authors.initials: V
authors.lastname: Milenković
authors.forename: Marina
authors.initials: M
authors.lastname: Delić
authors.forename: Sanja
authors.initials: S
authors.lastname: Mazić
authors.forename: Katarina
authors.initials: K
authors.lastname: Jeremic
authors.forename: Zlatko
authors.initials: Z
authors.lastname: Hrgović
keywords: Allergy; Etoposide; Gynecological malignancy