title: Psychopharmacologic treatment of borderline personality disorder.
abstract: The best available evidence for psychopharmacologic treatment of borderline personality disorder (BPD) is outlined here. BPD is defined by disturbances in identity and interpersonal functioning, and patients report potential medication treatment targets such as impulsivity, aggression, transient psychotic and dissociative symptoms, and refractory affective instability Few randomized controlled trials of psychopharmacological treatments for BPD have been published recently, although multiple reviews have converged on the effectiveness of specific anticonvulsants, atypical antipsychotic agents, and omega-3 fatty acid supplementation. Stronger evidence exists for medication providing significant improvements in impulsive aggression than in affective or other interpersonal symptoms. Future research strategies will focus on the potential role of neuropeptide agents and medications with greater specificity for 2A serotonin receptors, as well as optimizing concomitant implementation of evidence-based psychotherapy and psychopharmacology, in order to improve BPD patients' overall functioning.
authors.affiliation: Assistant Professor, Dept of Psychiatry, The Mount Sinai School of Medicine, New York, New York, USA.
authors.forename: Luis H
authors.initials: LH
authors.lastname: Ripoll
mesh_terms: D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001883:Borderline Personality Disorder / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents
keywords: aggression; borderline personality disorder; impulsivity; interpersonal; personality disorder; psychopharmacology