title: Assessment of leukocyte trafficking in humans using the cantharidin blister model.
abstract: The cantharidin blister model provides an in vivo assessment of the innate inflammatory response in humans. It allows researchers to profile the acute and resolving inflammatory response in healthy and diseased states and for the design of crossover trials for the testing of new treatments for acute inflammation. Below we describe the materials and methods required to prepare, induce, aspirate and analyse the forearm cantharidin blisters, in preparation for future study design.
authors.affiliation: Centre for Clinical Pharmacology, Division of Medicine, University College London , London WC1E 6JF , UK.
authors.forename: William J
authors.initials: WJ
authors.lastname: Jenner
authors.forename: Derek W
authors.initials: DW
authors.lastname: Gilroy