title: Antibiotic pressure mediated selection of non-biofilm forming strain of Elizabethkingia meningosepticum causing fatal nosocomial meningitis in a term infant.
abstract: We describe a fatal case of hospital acquired meningitis in a term infant due to the antibiotic pressure mediated selection of Elizabethkingia meningosepticum. The antibiotics were administered for multi-drug resistant Acinetobacter baumannii infection. The strain was also phenotypically characterized for beta lactamase production, biofilm forming capability and resistance to in use disinfectants.
authors.affiliation: Department of Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India.
authors.forename: Sumit
authors.initials: S
authors.lastname: Rai
authors.forename: Devendra Kumar
authors.initials: DK
authors.lastname: Niranjan
authors.forename: Prakash
authors.initials: P
authors.lastname: Mishra
authors.forename: Narendra Pal
authors.initials: NP
authors.lastname: Singh
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D018441:Biofilms / Q000254:growth & development; D003428:Cross Infection / Q000382:microbiology; D004202:Disinfectants / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D017809:Fatal Outcome; D005260:Female; D041965:Flavobacteriaceae / Q000187:drug effects* / Q000302:isolation & purification* / Q000502:physiology; D045826:Flavobacteriaceae Infections / Q000382:microbiology*; D006801:Humans; D007231:Infant, Newborn; D016920:Meningitis, Bacterial / Q000382:microbiology*; D012641:Selection, Genetic
chemical_list: D000900:Anti-Bacterial Agents; D004202:Disinfectants