title: Hepatic brucelloma.
abstract: We present a case of hepatic abscess caused by Brucella melitensis (or hepatic brucelloma) diagnosed in a 59-year-old man 33 years after an episode of acute brucellosis that had completely resolved. Recovery from symptoms and a decrease in lesion size seen on radiological assessment were achieved through prolonged combined antibiotic therapy, without the need for surgery. Hepatic brucelloma is a rare complication of brucellosis, which is the most common zoonosis globally, mainly occurring in specific endemic areas and causing a range of clinical manifestations. In this Grand Round, we review the clinical manifestations, diagnostic approach (through laboratory, radiology, and histology findings), differential diagnosis, treatment, and prognosis of hepatic brucelloma.
authors.affiliation: Emergency Department, Santa Croce and Carle General Hospital, Cuneo, Italy; School of Emergency Medicine, University of Turin, Turin, Italy. Electronic address: letiziabarutta@alice.it.
authors.forename: Letizia
authors.initials: L
authors.lastname: Barutta
authors.forename: Domenico
authors.initials: D
authors.lastname: Ferrigno
authors.forename: Remo
authors.initials: R
authors.lastname: Melchio
authors.forename: Valentina
authors.initials: V
authors.lastname: Borretta
authors.forename: Christian
authors.initials: C
authors.lastname: Bracco
authors.forename: Chiara
authors.initials: C
authors.lastname: Brignone
authors.forename: Alessia
authors.initials: A
authors.lastname: Giraudo
authors.forename: Cristina
authors.initials: C
authors.lastname: Serraino
authors.forename: Enrico
authors.initials: E
authors.lastname: Baralis
authors.forename: Maurizio
authors.initials: M
authors.lastname: Grosso
authors.forename: Luigi Maria
authors.initials: LM
authors.lastname: Fenoglio
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017347:Brucella melitensis / Q000302:isolation & purification*; D002006:Brucellosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008100:Liver Abscess / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D015047:Zoonoses / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents