title: Relevance of postprandial lipemia in metabolic syndrome.
abstract: Metabolic Syndrome (MetS) is a complex disorder defined by the aggregation of interconnected cardiometabolic risk factors which increase the risk of diabetes mellitus type 2 and cardiovascular disease (CVD). MetS is currently a matter of concern and it will continue to be in the future, since there is likely to be a dramatic increase in its prevalence, and subjects with MetS will have an increased risk of mortality, mainly through CVD. Moreover, the implications on the global health burden and the worldwide epidemic of this complex disorder will impact greatly on socioeconomic cost. MetS is therefore a matter of serious concern and we need to understand its etiology in order to improve strategies of treatment and prevention. In this regard, postprandial lipemia has increased in importance over the last few years as it has been demonstrated to influence the development of atherosclerosis. In addition, in modern times, fasting is not the typical physiological state of humans; in fact, they spend most of the time in the postprandial state. However, although it is obvious that postprandial lipemia is present in conditions of obesity, little is known about the relevance of postprandial lipemia in MetS. In the current review, we will explore some aspects of postprandial lipemia which could be of interest for understanding the pathogenesis of this complex disorder and which may help us advance towards more personalized nutrition.
authors.forename: Antonio
authors.initials: A
authors.lastname: Garcia-Rios
authors.forename: Javier
authors.initials: J
authors.lastname: Delgado-Lista
authors.forename: Pablo
authors.initials: P
authors.lastname: Perez-Martinez
authors.forename: Nieves
authors.initials: N
authors.lastname: Delgado-Casado
authors.forename: Francisco
authors.initials: F
authors.lastname: Perez-Jimenez
authors.affiliation: Servicio de Medicina Interna. Unidad de Lipidos y Arteriosclerosis. Hospital Universitario Reina Sofia. Edificio de Consultas Externas, 2ª planta. 14004 Cordoba, Spain. jlopezmir@uco.es.
authors.forename: Jose
authors.initials: J
authors.lastname: Lopez-Miranda
mesh_terms: D000818:Animals; D004730:Endothelium, Vascular / Q000378:metabolism / Q000473:pathology; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood* / Q000175:diagnosis / Q000453:epidemiology*; D024821:Metabolic Syndrome / Q000097:blood* / Q000175:diagnosis / Q000453:epidemiology*; D009765:Obesity / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology; D018384:Oxidative Stress / Q000502:physiology; D019518:Postprandial Period / Q000502:physiology*; D012307:Risk Factors