title: Assessment of liver function in two groups of outdoor workers exposed to arsenic.
abstract: OBJECTIVE
  To evaluate whether the exposure to arsenic (As) causes alterations of liver enzymes in two groups of outdoor workers.
  
  
  METHODS
  Total urinary As and the levels of AST/GOT, ALT/GPT, and GGT were measured on 80 traffic policemen and 50 police drivers. Personal air samples were obtained for assessing the exposure to As on a subgroup of 20 traffic policemen and 20 police drivers.
  
  
  RESULTS
  Mean values of personal exposure to As, urinary As, AST/GOT, and ALT/GPT were significantly higher in traffic policemen than in the police drivers. Multiple linear regression models showed associations between urinary As and airborne As, ALT/GPT and the job variables, and BMI and urinary As.
  
  
  CONCLUSIONS
  These findings contribute toward the evaluation of the hepatic effects of exposure to As in the urban workers.
authors.affiliation: Unit of Occupational Medicine, Department of Anatomy, Histology, Legal Medicine and Orthopedics, University of Rome "Sapienza", Viale Regina Elena 336, 00161, Rome, Italy, info@spinoff-sipro.it.
authors.forename: Teodorico
authors.initials: T
authors.lastname: Casale
authors.forename: Maria Valeria
authors.initials: MV
authors.lastname: Rosati
authors.forename: Manuela
authors.initials: M
authors.lastname: Ciarrocca
authors.forename: Ilaria
authors.initials: I
authors.lastname: Samperi
authors.forename: Giorgia
authors.initials: G
authors.lastname: Andreozzi
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: Schifano
authors.forename: Assunta
authors.initials: A
authors.lastname: Capozzella
authors.forename: Benedetta
authors.initials: B
authors.lastname: Pimpinella
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Tomei
authors.forename: Tiziana
authors.initials: T
authors.lastname: Caciari
authors.forename: Francesco
authors.initials: F
authors.lastname: Tomei
mesh_terms: D000328:Adult; D000395:Air Pollutants, Occupational / Q000494:pharmacology*; D001151:Arsenic / Q000494:pharmacology*; D004032:Diet; D004784:Environmental Monitoring; D006801:Humans; D007558:Italy; D008099:Liver / Q000201:enzymology*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D016495:Police; D014505:Urban Population
chemical_list: D000395:Air Pollutants, Occupational; D001151:Arsenic