title: A longitudinal study of hearing and middle ear status of individuals with cleft palate with and without additional malformations/syndromes.
abstract: Objective : To describe and compare the middle ear status and hearing sensitivity in adolescence with isolated cleft palate plus additional malformations and/or syndromes with those with only an isolated cleft palate. Design : Retrospective and longitudinal. Two groups of individuals with isolated cleft palate were compared. Participants : A cohort of individuals born over 4 years in the western region of Sweden. The cohort was divided into one group with isolated cleft palate (n = 31; ICP) and one group with isolated cleft palate plus additional malformations and/or syndromes (n = 37; ICP+). Methods : Middle ear status and hearing thresholds were collected from the medical records at 7, 10, 13, and 16 years of age, examined, and compared within and between groups over time. Results : The ICP+ group demonstrated a significantly higher prevalence of abnormal middle ear status and elevated hearing thresholds as compared with the ICP group. As the individuals aged, the prevalence of abnormal middle ear status decreased. The hearing levels in both groups decreased in the low to middle frequencies as individuals aged; however, the hearing in the high frequencies did not. Conclusions : Individuals with cleft palate need to be followed routinely for middle ear status and hearing thresholds to ensure optimal audiological rehabilitation, with particular attention to those with additional malformations and/or syndromes.
authors.forename: Traci
authors.initials: T
authors.lastname: Flynn
authors.forename: Christina
authors.initials: C
authors.lastname: Persson
authors.forename: Claes
authors.initials: C
authors.lastname: Moller
authors.forename: Anette
authors.initials: A
authors.lastname: Lohmander
authors.forename: Lennart
authors.initials: L
authors.lastname: Magnusson
mesh_terms: D000158:Acoustic Impedance Tests; D000293:Adolescent; D001301:Audiometry, Pure-Tone; D002648:Child; D002972:Cleft Palate / Q000453:epidemiology*; D004432:Ear, Middle / Q000002:abnormalities*; D005260:Female; D006311:Hearing Disorders / Q000453:epidemiology*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies; D013548:Sweden / Q000453:epidemiology; D013577:Syndrome
keywords: additional malformations; hearing; isolated cleft palate; middle ear status; syndromes