title: Copper-catalyzed gem-difluoroolefination of diazo compounds with TMSCF3 via C-F bond cleavage.
abstract: A novel Cu-catalyzed gem-difluoroolefination of diazo compounds is described. This transformation starts from readily available TMSCF3 and diazo compounds, via trifluoromethylation followed by C-F bond cleavage, to afford the desired 1,1-difluoroalkene products.
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Ling-Ling Road, Shanghai 200032, China.
authors.forename: Mingyou
authors.initials: M
authors.lastname: Hu
authors.forename: Zhengbiao
authors.initials: Z
authors.lastname: He
authors.forename: Bing
authors.initials: B
authors.lastname: Gao
authors.forename: Lingchun
authors.initials: L
authors.lastname: Li
authors.forename: Chuanfa
authors.initials: C
authors.lastname: Ni
authors.forename: Jinbo
authors.initials: J
authors.lastname: Hu
mesh_terms: D001391:Azo Compounds / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012821:Silanes / Q000737:chemistry*
chemical_list: D001391:Azo Compounds; D006845:Hydrocarbons, Fluorinated; D012821:Silanes; D003300:Copper; C509472:trimethyl(trifluoromethyl)silane