title: Surgery for giant primary neuroendocrine carcinoma of the liver.
abstract: Liver resection for primary hepatic neuroendocrine carcinoma (phNEC) has only scarcely been reported in the literature. We herein report on a 19-year-old female with a solitary 27 × 13-cm-big phNEC, which was initially considered as hemangioma. An extended right hepatectomy (segments V-VIII, partially IVa) was performed. Resection margins were free of tumor (R0 resection). Ki67 expression was 35%. Postoperative course was uneventful, and the patient was discharged on the seventh postoperative day. Two years after surgery, the patient remains disease-free and in good general condition. Large series and longer follow-up studies are required for the better understanding on this rare tumor entity.
authors.affiliation: 2nd Department of Propedeutic Surgery, University of Athens Medical School, Athens, Greece, georgios.sotiropoulos@uni-due.de.
authors.forename: Georgios C
authors.initials: GC
authors.lastname: Sotiropoulos
authors.forename: Petros
authors.initials: P
authors.lastname: Charalampoudis
authors.forename: Ioanna
authors.initials: I
authors.lastname: Delladetsima
authors.forename: Paraskevas
authors.initials: P
authors.lastname: Stamopoulos
authors.forename: Spyridon
authors.initials: S
authors.lastname: Dourakis
authors.forename: Gregory
authors.initials: G
authors.lastname: Kouraklis
mesh_terms: D018278:Carcinoma, Neuroendocrine / Q000737:chemistry / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D019394:Ki-67 Antigen / Q000032:analysis; D008113:Liver Neoplasms / Q000737:chemistry / Q000473:pathology / Q000601:surgery*; D047368:Tumor Burden; D055815:Young Adult
chemical_list: D019394:Ki-67 Antigen