title: Trace analysis of biocidal oligoguanidines in environmental water samples.
abstract: This paper demonstrates the determination of residues of biocidal oligoguanidines manufactured by polycondensation of guanidine hydrochloride and 2,2'-(ethylenedioxy)bis(ethylamine) in environmental water samples. The analytes were preconcentrated from samples adjusted to pH 4 by solid-phase extraction using a mixed-mode sorbent with weak cation exchange functionalities. Elution from the sorbent was achieved by 2M hydrochloric acid in methanol. After evaporation and reconstitution in water, the extract was analyzed by reversed-phase high performance liquid chromatography combined with quadrupole/time-of-flight or triple quadrupole mass spectrometry employing electrospray ionization. A preconcentration factor of 10,000 could be achieved and detection limits were in the sub-μgL(-1) range. This method looks promising to monitor the fate of these biocides released into the aquatic environment during different applications.
authors.affiliation: Johannes-Kepler-University Linz, Institute of Analytical Chemistry, Altenbergerstrasse 69, A-4040 Linz, Austria. Electronic address: tamara.buchberger@jku.at.
authors.forename: Tamara
authors.initials: T
authors.lastname: Buchberger
authors.forename: Markus
authors.initials: M
authors.lastname: Himmelsbach
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Buchberger
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004202:Disinfectants / Q000737:chemistry* / Q000302:isolation & purification; D019791:Guanidine / Q000031:analogs & derivatives / Q000032:analysis* / Q000302:isolation & purification; D057230:Limit of Detection; D052616:Solid Phase Extraction; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000302:isolation & purification
chemical_list: D004202:Disinfectants; D014874:Water Pollutants, Chemical; D019791:Guanidine
keywords: Biocidal oligomeric guanidines; Liquid chromatography; Mass spectrometry; Residue analysis; Time-of-flight; Triple quadrupole