title: A Case of Nephrotic Syndrome With Minimal-Change Disease and Waldenstrom's Macroglobulinemia.
abstract: Kidney disease is a rare complication of Waldenstrom's macroglobulinemia. We report a case of nephrotic syndrome and minimal change disease in a patient with biopsy proven Waldenstrom's macroglobulinemia. The patient presented with over 12 grams of proteinuria and was successfully treated with oral prednisone over the course of 4 weeks. Repeat serum protein electrophoresis as well as serum immunoelectrophoresis revealed no paraproteins, urine analysis was negative for protein or blood by dipstick and spot urine protein was 9 mg/dL with creatinine of 101 mg/dL at time of last office visit. This case illustrates the successful treatment with corticosteroids alone with prolonged complete remission.
authors.affiliation: Albany Medical College, 47 New Scotland Avenue, Albany, N.Y. 12208, USA ; Albany College of Pharmacy and Health Sciences, 106 New Scotland Avenue, Albany, N.Y. 12208, USA ; Albany Nephrology Pharmacy Group (ANephRx), USA.
authors.forename: Darren W
authors.initials: DW
authors.lastname: Grabe
authors.forename: Bo
authors.initials: B
authors.lastname: Li
authors.forename: Syed S
authors.initials: SS
authors.lastname: Haqqie
keywords: Minimal change disease; Nephrotic syndrome; Waldenstrom’s macroglobulinemia