title: Three new ursane-type triterpenoids from the aerial parts of Isodon excisoides.
abstract: Three new ursane-type triterpenoids, 2α,3β-dihydroxy-11α,12α-epoxy-urs-28,13β-olide (1), 2α,3β,24-trihydroxy-11α,12α-epoxy-urs-28,13β-olide (2), and 2α,3α,24-trihydroxy-11,20(30)-dien-urs-28,13β-olide (6), together with six known ursane-type triterpenoids (3-5, 7-9), were isolated from the EtOAc extract of the aerial parts of Isodon excisoides. Their structures were elucidated on the basis of 1D NMR and 2D NMR analyses as well as HRMS experiments.
authors.affiliation: a Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji School of Pharmaceutical Sciences, Huazhong University of Science and Technology , Wuhan , 430030 , China.
authors.forename: Ke
authors.initials: K
authors.lastname: Jiao
authors.forename: Huo-Yun
authors.initials: HY
authors.lastname: Li
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
authors.forename: Hui-Fang
authors.initials: HF
authors.lastname: Pi
authors.forename: Han-Li
authors.initials: HL
authors.lastname: Ruan
authors.forename: Ji-Zhou
authors.initials: JZ
authors.lastname: Wu
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D037602:Isodon / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: C585698:2alpha,3alpha,24-trihydroxy-11,20(30)-dien-urs-28,13beta-olide; C585699:2alpha,3beta,24-trihydroxy-11alpha,12alpha-epoxy-urs-28,13beta-olide; C585697:2alpha,3beta-dihydroxy-11alpha,12alpha-epoxy-urs-28,13beta-olide; D004365:Drugs, Chinese Herbal; D014315:Triterpenes