title: Hepato-pancreato-biliary lesions are present in both Carney complex and McCune Albright syndrome: comments on P. Salpea and C. Stratakis.
abstract: One of the key messages of recent Salpea and Stratakis work is to underline the clinical similarities shared by these syndromes that could be explained by a defect in the same signaling pathway, i.e. activation of the cAMP pathway. That being said, we would like to emphasize that hepatopancreato-biliary lesions are one additional feature shared both by Carney complex and McCune Albright syndrome.
authors.affiliation: AP-HP, Hôpital Beaujon, Department of Hepato-Pancreato-Biliary Surgery - Pôle des Maladies de l'Appareil Digestif (PMAD), Clichy 92110, France; Institut National de la Santé et de la Recherche Médicale, U773, Groupe Hospitalier Paris Nord Val de Seine, Paris, France; Université Paris Diderot, Paris, France. Electronic address: sebastien.gaujoux@gmail.com.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Gaujoux
authors.affiliation: AP-HP, Centre de Référence des Maladies Endocriniennes Rares de la Croissance, Service d'Endocrinologie et des Maladies de la Reproduction, Hôpital Bicêtre, Le Kremlin Bicêtre F-94275, France; Université Paris-Sud 11, UMR 693, F-94276 Le Kremlin-Bicêtre, France; Institut National de la Santé et de la Recherche Médicale, U986, Groupe hospitalier Paris-Sud, 94270 Le Kremlin-Bicêtre, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Chanson
authors.affiliation: Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France; Institut National de la Santé et de la Recherche Médicale, U1016 Paris, France; Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Department of Endocrinology, Reference Center for Rare Adrenal Diseases, Paris, France; INCa Comete Network, Assistance Publique des Hôpitaux de Paris, Hôpital Cochin, 75014 Paris, France.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Bertherat
authors.affiliation: AP-HP, Hôpital Beaujon, Department of Hepato-Pancreato-Biliary Surgery - Pôle des Maladies de l'Appareil Digestif (PMAD), Clichy 92110, France; Institut National de la Santé et de la Recherche Médicale, U773, Groupe Hospitalier Paris Nord Val de Seine, Paris, France; Université Paris Diderot, Paris, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Sauvanet
authors.affiliation: Institut National de la Santé et de la Recherche Médicale, U773, Groupe Hospitalier Paris Nord Val de Seine, Paris, France; Université Paris Diderot, Paris, France; AP-HP, Hôpital Beaujon, Department of Gastroenterology, Pôle des Maladies de l'Appareil Digestif (PMAD), Clichy 92110, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Ruszniewski
mesh_terms: D001652:Bile Ducts / Q000378:metabolism / Q000473:pathology*; D056733:Carney Complex / Q000473:pathology*; D005359:Fibrous Dysplasia, Polyostotic / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000378:metabolism / Q000473:pathology*; D010179:Pancreas / Q000378:metabolism / Q000473:pathology*
keywords: Carney complex; GNAS; IPMN; McCune Albright syndrome