title: [Skin antisepsis with 0.05% sodium hypochlorite before the insertion of a peripheral venous catheter in adults, children and newborns].
abstract: BACKGROUND
  Antisepsis of the skin of adults, children and newborns before the insertion of a peripheral venous catheter (PVC) reduces the risk of catheter related infections (CRI). Data on the effectiveness of electrolytic sodium hypochlorite are missing.
  
  
  METHODS
  An explorative study was conducted on children, adults and newborns admitted to hospital and with skin antisepsis with sodium hypoclorite 0.057g with active chlorine 0.055g in 100ml (Amukine Med®) to assess the level of contamination of PVC tips, as surrogate sign of infection. Quantitative methods were used and the catheter tip was considered colonized if >1000 CFU (colony forming Units)/catheter segment.
  
  
  RESULTS
  In the sample of 42 adults, 51 children and 52 newborns, 16.7%, 7.8% and 3.8% of catheter tips were contaminated respectively. No catheter related phlebites were observed.
  
  
  CONCLUSIONS
  Skin antisepsis with Amukine Med® seems effective in preventing CRIs but further comparative studies are needed with the antiseptics recommended by guidelines.
authors.forename: Paolo
authors.initials: P
authors.lastname: Chiari
authors.forename: Cristiana
authors.initials: C
authors.lastname: Forni
authors.forename: Ambra
authors.initials: A
authors.lastname: Fiorani
authors.forename: Olimpia
authors.initials: O
authors.lastname: Pezzullo
authors.forename: Veronica
authors.initials: V
authors.lastname: Ricciardi
authors.forename: Domenica
authors.initials: D
authors.lastname: Gazineo
authors.forename: Lucia
authors.initials: L
authors.lastname: Caso
authors.forename: Tania
authors.initials: T
authors.lastname: Sabattini
authors.forename: Fabio
authors.initials: F
authors.lastname: D'Alessandro
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D000985:Antisepsis / Q000379:methods*; D055499:Catheter-Related Infections / Q000451:nursing* / Q000517:prevention & control; D002406:Catheterization, Peripheral / Q000451:nursing*; D002648:Child; D006801:Humans; D007231:Infant, Newborn; D007362:Intensive Care Units; D011446:Prospective Studies; D012867:Skin / Q000187:drug effects* / Q000382:microbiology; D012973:Sodium Hypochlorite / Q000008:administration & dosage*
chemical_list: D000891:Anti-Infective Agents, Local; D012973:Sodium Hypochlorite