title: Use of the 46/1 haplotype to model JAK2(V617F) clonal architecture in PV patients: clonal evolution and impact of IFNα treatment.
authors.affiliation: 1] INSERM, UMR 1009, Laboratory of Excellence GR-Ex, Villejuif, France [2] Université Paris-Sud, UMR 1009, Institut Gustave Roussy, Villejuif, France [3] Gustave Roussy, Institut Gustave Roussy, Villejuif, France.
authors.forename: S
authors.initials: S
authors.lastname: Hasan
authors.affiliation: AP-HP, Service de Biologie Cellulaire, Hôpital Saint-Louis, Paris, France.
authors.forename: B
authors.initials: B
authors.lastname: Cassinat
authors.affiliation: 1] INSERM, UMR 1009, Laboratory of Excellence GR-Ex, Villejuif, France [2] Université Paris-Sud, UMR 1009, Institut Gustave Roussy, Villejuif, France [3] Gustave Roussy, Institut Gustave Roussy, Villejuif, France.
authors.forename: N
authors.initials: N
authors.lastname: Droin
authors.affiliation: 1] INSERM, UMR 1009, Laboratory of Excellence GR-Ex, Villejuif, France [2] Université Paris-Sud, UMR 1009, Institut Gustave Roussy, Villejuif, France [3] Gustave Roussy, Institut Gustave Roussy, Villejuif, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Le Couedic
authors.affiliation: 1] INSERM, UMR 1009, Laboratory of Excellence GR-Ex, Villejuif, France [2] Université Paris-Sud, UMR 1009, Institut Gustave Roussy, Villejuif, France [3] Gustave Roussy, Institut Gustave Roussy, Villejuif, France.
authors.forename: F
authors.initials: F
authors.lastname: Favale
authors.affiliation: 1] INSERM, UMR 1009, Laboratory of Excellence GR-Ex, Villejuif, France [2] Université Paris-Sud, UMR 1009, Institut Gustave Roussy, Villejuif, France [3] Gustave Roussy, Institut Gustave Roussy, Villejuif, France.
authors.forename: B
authors.initials: B
authors.lastname: Monte-Mor
authors.affiliation: 1] INSERM, UMR 1009, Laboratory of Excellence GR-Ex, Villejuif, France [2] Université Paris-Sud, UMR 1009, Institut Gustave Roussy, Villejuif, France [3] Gustave Roussy, Institut Gustave Roussy, Villejuif, France.
authors.forename: C
authors.initials: C
authors.lastname: Lacout
authors.affiliation: AP-HP, Hôpital Cochin, Service d'Hématologie biologique, Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Fontenay
authors.affiliation: AP-HP, Service de Biologie Cellulaire, Hôpital Saint-Louis, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Dosquet
authors.affiliation: 1] AP-HP, Service de Biologie Cellulaire, Hôpital Saint-Louis, Paris, France [2] Université Paris-Diderot, Sorbonne Paris Cité, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Chomienne
authors.affiliation: 1] INSERM, UMR 1009, Laboratory of Excellence GR-Ex, Villejuif, France [2] Université Paris-Sud, UMR 1009, Institut Gustave Roussy, Villejuif, France [3] Gustave Roussy, Institut Gustave Roussy, Villejuif, France.
authors.forename: E
authors.initials: E
authors.lastname: Solary
authors.affiliation: 1] INSERM, UMR 1009, Laboratory of Excellence GR-Ex, Villejuif, France [2] Université Paris-Sud, UMR 1009, Institut Gustave Roussy, Villejuif, France [3] Gustave Roussy, Institut Gustave Roussy, Villejuif, France.
authors.forename: J L
authors.initials: JL
authors.lastname: Villeval
authors.affiliation: 1] INSERM, UMR 1009, Laboratory of Excellence GR-Ex, Villejuif, France [2] AP-HP, Laboratoire d'hématologie, Hôpital Saint Antoine, Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Casadevall
authors.affiliation: AP-HP, Centre d'Investigations Cliniques, Hôpital Saint-Louis, Paris, France.
authors.forename: J J
authors.initials: JJ
authors.lastname: Kiladjian
authors.affiliation: 1] INSERM, UMR 1009, Laboratory of Excellence GR-Ex, Villejuif, France [2] Université Paris-Sud, UMR 1009, Institut Gustave Roussy, Villejuif, France [3] Gustave Roussy, Institut Gustave Roussy, Villejuif, France.
authors.forename: W
authors.initials: W
authors.lastname: Vainchenker
authors.affiliation: 1] INSERM, UMR 1009, Laboratory of Excellence GR-Ex, Villejuif, France [2] Université Paris-Sud, UMR 1009, Institut Gustave Roussy, Villejuif, France [3] Gustave Roussy, Institut Gustave Roussy, Villejuif, France.
authors.forename: I
authors.initials: I
authors.lastname: Plo
mesh_terms: D000483:Alleles; D060965:Clonal Evolution; D006239:Haplotypes; D006412:Hematopoietic Stem Cells / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D053614:Janus Kinase 2 / Q000235:genetics*; D008954:Models, Biological; D009154:Mutation; D011087:Polycythemia Vera / Q000188:drug therapy / Q000235:genetics* / Q000378:metabolism*
chemical_list: D016898:Interferon-alpha; D053614:Janus Kinase 2