title: Madura foot: two case reports, review of the literature, and new developments with clinical correlation.
abstract: "Madura foot" or pedal mycetoma is a rare destructive infection of the skin and subcutaneous tissues of the foot, progressing to involve muscle and bone. The infection can be caused by both bacteria and fungi. Infection typically follows traumatic implantation of bacteria or fungal spores, which are present in soil or on plant material. Clinically, this entity can be difficult to diagnose and can have an indolent and progressive course. Early diagnosis is important to prevent patient morbidity and mortality. We present two cases of pedal mycetoma, review the literature, review new developments in diagnosis, and discuss magnetic resonance imaging (MRI) features of this unusual entity.
authors.affiliation: Department of Radiology, University of Southern California, 1520 San Pablo Street, Suite L-1600, Los Angeles, CA, 90033, USA, ericwhiteusc@gmail.com.
authors.forename: Eric A
authors.initials: EA
authors.lastname: White
authors.forename: Dakshesh B
authors.initials: DB
authors.lastname: Patel
authors.forename: Deborah M
authors.initials: DM
authors.lastname: Forrester
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Gottsegen
authors.forename: Emily
authors.initials: E
authors.lastname: O'Rourke
authors.forename: Paul
authors.initials: P
authors.lastname: Holtom
authors.forename: Timothy
authors.initials: T
authors.lastname: Charlton
authors.forename: George R
authors.initials: GR
authors.lastname: Matcuk
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D005533:Foot Dermatoses / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008911:Minocycline / Q000627:therapeutic use*; D010019:Osteomyelitis / Q000175:diagnosis* / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D008911:Minocycline