title: Successful Salvage Chemotherapy with FOLFIRINOX for Recurrent Mixed Acinar Cell Carcinoma and Ductal Adenocarcinoma of the Pancreas in an Adolescent Patient.
abstract: Pancreatic tumors are rare in children and adolescents. Here, we report the case of a 15-year-old boy who presented with a mixed acinar cell carcinoma/ductal adenocarcinoma with blastomatous components. He received multimodal treatment including various chemotherapy regimens and multistep surgery including liver transplantation. Introduction of FOLFIRINOX after relapse repeatedly achieved a durable metabolic and clinical response with good quality of life.
authors.affiliation: Department of Oncology, University Hospital Zurich, Switzerland.
authors.forename: Sarah
authors.initials: S
authors.lastname: Pfrommer
authors.forename: Achim
authors.initials: A
authors.lastname: Weber
authors.forename: Philipp
authors.initials: P
authors.lastname: Dutkowski
authors.forename: Niklaus G
authors.initials: NG
authors.lastname: Schäfer
authors.forename: Beat
authors.initials: B
authors.lastname: Müllhaupt
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Bourquin
authors.forename: Stefan
authors.initials: S
authors.lastname: Breitenstein
authors.forename: Bernhard C
authors.initials: BC
authors.lastname: Pestalozzi
authors.forename: Frank
authors.initials: F
authors.lastname: Stenner
authors.forename: Christoph
authors.initials: C
authors.lastname: Renner
authors.forename: Giannicola
authors.initials: G
authors.lastname: D'Addario
authors.forename: Hans-Jörg
authors.initials: HJ
authors.lastname: Graf
authors.forename: Alexander
authors.initials: A
authors.lastname: Knuth
authors.forename: Pierre-Alain
authors.initials: PA
authors.lastname: Clavien
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Samaras
keywords: Acinar cell carcinoma; Autologous stem cell transplantation; Ductal adenocarcinoma; FOLFIRINOX; Multimodal treatment; Pancreatic cancer; Pancreatoblastoma