title: Whole-exome sequencing identifies a novel somatic mutation in MMP8 associated with a t(1;22)-acute megakaryoblastic leukemia.
authors.affiliation: 1] Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA [2] Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: V P
authors.initials: VP
authors.lastname: Schulz
authors.affiliation: Section of Hematology/Oncology, Department of Pediatrics, University of California, Davis, Comprehensive Cancer Center, Sacramento, CA, USA.
authors.forename: N
authors.initials: N
authors.lastname: Satake
authors.affiliation: 1] Departments of Oncology, St Jude Children's Research Hospital, Memphis, TN, USA [2] Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.
authors.forename: T A
authors.initials: TA
authors.lastname: Gruber
authors.affiliation: 1] Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA [2] Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA [3] Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Teixeira
authors.affiliation: Yale Comprehensive Cancer Center, Division of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: S
authors.initials: S
authors.lastname: Halene
authors.affiliation: 1] Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA [2] Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: P G
authors.initials: PG
authors.lastname: Gallagher
authors.affiliation: 1] Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA [2] Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA [3] Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: D S
authors.initials: DS
authors.lastname: Krause
mesh_terms: D002648:Child; D002878:Chromosomes, Human, Pair 1; D002892:Chromosomes, Human, Pair 22; D004268:DNA-Binding Proteins / Q000235:genetics; D059472:Exome; D006801:Humans; D007947:Leukemia, Megakaryoblastic, Acute / Q000188:drug therapy / Q000235:genetics*; D008297:Male; D020784:Matrix Metalloproteinase 8 / Q000235:genetics*; D009154:Mutation; D015514:Oncogene Proteins, Fusion / Q000235:genetics; D020641:Polymorphism, Single Nucleotide; D016601:RNA-Binding Proteins / Q000235:genetics; D015534:Trans-Activators; D014178:Translocation, Genetic
chemical_list: D004268:DNA-Binding Proteins; C431575:MRTFA protein, human; D015514:Oncogene Proteins, Fusion; C431574:RBM15 protein, human; D016601:RNA-Binding Proteins; D015534:Trans-Activators; C488762:MMP8 protein, human; D020784:Matrix Metalloproteinase 8