title: Two birds with one stone: multifunctional and highly selective fluorescent probe for distinguishing Zn2+ from Cd2+ and selective recognition of sulfide anion.
abstract: A coumarin-based multifunctional fluorescent sensor containing a di-2-picolylamine (DPA) moiety (1) was presented. Interestingly, this probe could similarly act as ON-OFF type fluorescent sensor for Co(2+) and Cu(2+), then in situ generated 1-Co(II) and 1-Cu(II) ensembles could further serve as OFF-ON type fluorescent sensors to achieve the discrimination of Zn(2+) from Cd(2+) and selective recognition of sulfide anion in aqueous solution via displacement approach, respectively. Specially, 1-Cu(II) could permeate the cell membrane and could be used in fluorescence imaging of S(2-) in living biological samples. These ON-OFF-ON type fluorescent sensors exhibited high selectivity and sensitivity towards the targets.
authors.affiliation: Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, PR China.
authors.forename: Ji-Ting
authors.initials: JT
authors.lastname: Hou
authors.forename: Bei-Yu
authors.initials: BY
authors.lastname: Liu
authors.forename: Kun
authors.initials: K
authors.lastname: Li
authors.forename: Kang-Kang
authors.initials: KK
authors.lastname: Yu
authors.forename: Ming-Bo
authors.initials: MB
authors.lastname: Wu
authors.forename: Xiao-Qi
authors.initials: XQ
authors.lastname: Yu
mesh_terms: D002413:Cations, Divalent; D002463:Cell Membrane Permeability; D003035:Cobalt / Q000032:analysis*; D003300:Copper / Q000032:analysis*; D003374:Coumarins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D012680:Sensitivity and Specificity; D012996:Solutions; D013050:Spectrometry, Fluorescence / Q000379:methods; D013440:Sulfides / Q000032:analysis*; D014867:Water / Q000737:chemistry; D015032:Zinc / Q000032:analysis*
chemical_list: D002413:Cations, Divalent; D003374:Coumarins; D005456:Fluorescent Dyes; D012996:Solutions; D013440:Sulfides; D014867:Water; D003035:Cobalt; D003300:Copper; D015032:Zinc
keywords: Fluorescent probe; Recognition; Sulfide anion; Zinc ion