title: [Obesity and hypertension].
abstract: The frequency of hypertension and obesity is gradually growing in Hungary. At present 68.5% of men and 78% of women are obese. Hypertension and obesity are the most important risk factors of morbidity and mortality from cardiovascular disease. The relationship between increased sympathetic activity and hypertension is well known. Waist circumference and body fat mass correlate significantly with sympathetic activity, in which hyperlipidemia plays also a role. The increased activity of renin-angiotensin-aldosterone system via its vascular and renal effects also contributes to an increase of blood pressure. Increased sympathetic activity with decreasing vagal tone accompanying the imbalance of the autonomous nervous system is independent and significant risk factor of cardiovascular events including sudden cardiac death.
authors.affiliation: Szent Imre Egyetemi Oktatókórház Anyagcsere Központ Budapest Tétényi út 12-16. 1115.
authors.forename: Gábor
authors.initials: G
authors.lastname: Simonyi
authors.forename: Réka
authors.initials: R
authors.lastname: Kollár
mesh_terms: D054392:Adipokines / Q000378:metabolism; D001794:Blood Pressure; D004730:Endothelium, Vascular / Q000503:physiopathology; D005260:Female; D006801:Humans; D006946:Hyperinsulinism / Q000209:etiology / Q000503:physiopathology; D006973:Hypertension / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology*; D007668:Kidney / Q000503:physiopathology*; D008297:Male; D009765:Obesity / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology*; D012084:Renin-Angiotensin System; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000209:etiology / Q000503:physiopathology
chemical_list: D054392:Adipokines
keywords: elhízás; fokozott szimpatikus aktivitás; hypertension; hypertonia; increased sympathetic activity; obesity