title: Comparative analysis of flavonoids and polar metabolites from hairy roots of Scutellaria baicalensis and Scutellaria lateriflora.
abstract: Baicalin, baicalein, and wogonin were accumulated in hairy roots derived from Scutellaria lateriflora and Scutellaria baicalensis. The levels of baicalein and baicalin were 6.8 and 5.0 times higher, respectively, in S. baicalensis than in S. lateriflora. A total of 47 metabolites were detected and identified in Scutellaria species by GC-TOF MS. The metabolites from the two species were subjected to principal component analysis (PCA) to evaluate differences. PCA fully distinguished between the two species. The results showed that individual phenolic acids and phenylalanine, precursors for the phenylpropanoid biosynthetic pathway, were higher in S. baicalensis than in S. lateriflora. This GC-TOF MS-based metabolic profiling approach was a viable alternative method to differentiate metabolic profiles between species.
authors.affiliation: Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, 406-772, Korea.
authors.forename: Jae Kwang
authors.initials: JK
authors.lastname: Kim
authors.forename: Young Seon
authors.initials: YS
authors.lastname: Kim
authors.forename: Yeji
authors.initials: Y
authors.lastname: Kim
authors.forename: Md Romij
authors.initials: MR
authors.lastname: Uddin
authors.forename: Yeon Bok
authors.initials: YB
authors.lastname: Kim
authors.forename: Haeng Hoon
authors.initials: HH
authors.lastname: Kim
authors.forename: Soo Yun
authors.initials: SY
authors.lastname: Park
authors.forename: Mi Young
authors.initials: MY
authors.lastname: Lee
authors.forename: Sun Ok
authors.initials: SO
authors.lastname: Chung
authors.forename: Sang Un
authors.initials: SU
authors.lastname: Park
mesh_terms: D005419:Flavonoids / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D018517:Plant Roots / Q000737:chemistry*; D031363:Scutellaria / Q000737:chemistry*
chemical_list: D005419:Flavonoids