title: Sensitivity Analysis of the Parameters of Korea's Pandemic Influenza Preparedness Plan.
abstract: OBJECTIVE
  Our aim was to evaluate Korea's Pandemic Influenza Preparedness Plan.
  
  
  METHODS
  We conducted a sensitivity analysis on the expected number of outpatients and hospital bed occupancy, with 1,000,000 parameter combinations, in a situation of pandemic influenza, using the mathematical simulation program InfluSim.
  
  
  RESULTS
  Given the available resources in Korea, antiviral treatment and social distancing must be combined to reduce the number of outpatients and hospitalizations sufficiently; any single intervention is not enough. The antiviral stockpile of 4-6% is sufficient for the expected eligible number of cases to be treated. However, the eligible number assumed (30% for severe cases and 26% for extremely severe cases) is very low compared to the corresponding number in European countries, where up to 90% of the population are assumed to be eligible for antiviral treatment.
  
  
  CONCLUSIONS
  A combination of antiviral treatment and social distancing can mitigate a pandemic, but will only bring it under control for the most optimistic parameter combinations.
authors.affiliation: Division of Epidemic Intelligence Service, Korea Centers for Disease Control and Prevention, Osong, Korea.
authors.forename: Chaeshin
authors.initials: C
authors.lastname: Chu
authors.forename: Junehawk
authors.initials: J
authors.lastname: Lee
authors.forename: Dong Hoon
authors.initials: DH
authors.lastname: Choi
authors.forename: Seung-Ki
authors.initials: SK
authors.lastname: Youn
authors.forename: Jong-Koo
authors.initials: JK
authors.lastname: Lee
keywords: influenza pandemic; preparedness planning; sensitivity analysis