title: [Off-label use of alitretinoin].
abstract: Oral alitretinoin (9-cis retinoic acid) is an endogenous retinoid related to vitamin A. Studies have shown that oral alitretinoin is effective and well-tolerated in the treatment of severe chronic hand eczema, so that it is approved for this indication. This review summarizes new studies and clinical experience on the off-label use of alitretinoin.
authors.affiliation: Haut und Laser Centrum - Landau, Reduitstr. 13, 76829, Landau, Deutschland, drklausfritz@t-online.de.
authors.forename: K
authors.initials: K
authors.lastname: Fritz
authors.forename: G S
authors.initials: GS
authors.lastname: Tiplica
authors.forename: C
authors.initials: C
authors.lastname: Salavastru
authors.forename: M
authors.initials: M
authors.lastname: Onder
mesh_terms: D000077556:Alitretinoin; D002908:Chronic Disease; D003879:Dermatologic Agents / Q000009:adverse effects / Q000627:therapeutic use; D064420:Drug-Related Side Effects and Adverse Reactions / Q000209:etiology* / Q000517:prevention & control; D004485:Eczema / Q000188:drug therapy*; D019317:Evidence-Based Medicine; D006229:Hand Dermatoses / Q000188:drug therapy*; D006801:Humans; D056687:Off-Label Use; D016896:Treatment Outcome; D014212:Tretinoin / Q000009:adverse effects* / Q000627:therapeutic use*
chemical_list: D003879:Dermatologic Agents; D000077556:Alitretinoin; D014212:Tretinoin