title: Synthesis of isoquinolines via Rh(III)-catalyzed C-H activation using hydrazone as a new oxidizing directing group.
abstract: An efficient and mechanistically interesting method for the synthesis of highly substituted isoquinolines by a Rh(III)-catalyzed hydrazone directed ortho C-H bond activation and annulation without an external oxidant is described. This reaction is accomplished via a C-C and C-N bond formation along with N-N bond cleavage.
authors.affiliation: Department of Chemistry, National Tsing Hua University , Hsinchu 30013, Taiwan.
authors.forename: Sheng-Chieh
authors.initials: SC
authors.lastname: Chuang
authors.forename: Parthasarathy
authors.initials: P
authors.lastname: Gandeepan
authors.forename: Chien-Hong
authors.initials: CH
authors.lastname: Cheng
mesh_terms: D002384:Catalysis; D006835:Hydrazones / Q000737:chemistry*; D006860:Hydrogen Bonding; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*
chemical_list: D006835:Hydrazones; D007546:Isoquinolines; D012238:Rhodium