title: Comparative review of interferometric detection of plasmonic nanoparticles.
abstract: Noble metal nanoparticles exhibit enhanced scattering and absorption at specific wavelengths due to a localized surface plamson resonance. This unique property can be exploited to enable the use of plasmonic nanoparticles as contrast agents in optical imaging. A range of optical techniques have been developed to detect nanoparticles in order to implement imaging schemes. Here we review several different approaches for using optical interferometry to detect the presence and concentration of nanoparticles. The strengths and weaknesses of the various approaches are discussed and quantitative comparisons of the achievable signal to noise ratios are presented. The benefits of each approach are outlined as they relate to specific application goals.
authors.affiliation: Department of Biomedical Engineering and Fitzpatrick Institute for Photonics, Duke University, Durham NC 27708, USA.
authors.forename: Adam
authors.initials: A
authors.lastname: Wax
authors.forename: Amihai
authors.initials: A
authors.lastname: Meiri
authors.forename: Siddarth
authors.initials: S
authors.lastname: Arumugam
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Rinehart
keywords: (120.3180) Interferometry; (160.4236) Nanomaterials; (170.1650) Coherence imaging