title: Prevalence of dementia and subtypes in Valladolid, northwestern Spain: the DEMINVALL study.
abstract: OBJECTIVE
  To describe the prevalence of dementia and subtypes in a general elderly population in northwestern Spain and to analyze the influence of socio-demographic factors.
  
  
  METHODS
  Cross-sectional, two-phase, door-to-door, population-based study. A total of 870 individuals from a rural region and 2,119 individuals from an urban region of Valladolid, Spain, were involved. The seven-minute screen neurocognitive battery was used in the screening phase. A control group was included.
  
  
  RESULTS
  A total of 2,170 individuals aged 65 to 104 years (57% women) were assessed. There were 184 subjects diagnosed with dementia. The crude prevalence was 8.5% (95% CI: 7.3-9.7). Age- and sex-adjusted prevalence was 5.5 (95% CI: 4.5-6.5). Main subtypes of dementia were: Alzheimer's disease (AD) 77.7%, Lewy Body disease, 7.6% and vascular dementia (VD) 5.9%. Crude prevalences were 6.6% (AD), 0.6% (Lewy Body disease), and 0.5% (VD). Dementia was associated with age (OR 1.14 for 1-year increase in age), female sex (OR 1.79) and the absence of formal education (OR 2.53 compared to subjects with primary education or more).
  
  
  CONCLUSIONS
  The prevalence of dementia in the study population was lower than the most recent estimates for Western Europe. There was a high proportion of AD among all dementia cases and very low prevalence of VD. Old age, female sex, and low education level were independent risk factors for dementia and AD.
authors.affiliation: Department of Neurology, Hospital Universitario Río Hortega, Valladolid, Spain.
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: Tola-Arribas
authors.forename: María Isabel
authors.initials: MI
authors.lastname: Yugueros
authors.forename: María José
authors.initials: MJ
authors.lastname: Garea
authors.forename: Fernando
authors.initials: F
authors.lastname: Ortega-Valín
authors.forename: Ana
authors.initials: A
authors.lastname: Cerón-Fernández
authors.forename: Beatriz
authors.initials: B
authors.lastname: Fernández-Malvido
authors.forename: Antonio
authors.initials: A
authors.lastname: San José-Gallegos
authors.forename: Marta
authors.initials: M
authors.lastname: González-Touya
authors.forename: Ana
authors.initials: A
authors.lastname: Botrán-Velicia
authors.forename: Vanessa
authors.initials: V
authors.lastname: Iglesias-Rodríguez
authors.forename: Bárbara
authors.initials: B
authors.lastname: Díaz-Gómez
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000453:epidemiology; D003704:Dementia / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012959:Socioeconomic Factors; D013030:Spain / Q000453:epidemiology