title: Prevalence and risk factors of onychomycosis in primary school children living in rural and urban areas in Central Anatolia of Turkey.
abstract: BACKGROUND
  Onychomycosis is a world-wide public health concern in children, requiring epidemiological data for different regions for control and prevention.
  
  
  OBJECTIVE
  The aim of this study was to evaluate the predominant pathogens and risk factors for onychomycosis in school children living in Kayseri, Turkey.
  
  
  METHODS
  This study included 8122 school children, aged 5-16 years, living in the rural and urban areas around Kayseri. Onychomycosis was clinically classified as distal and lateral subungual (DLSO), proximal subungual, superficial white, endonyx and totally dystrophic onychomycosis. Nail samples from children with clinically diagnosed onychomycosis were collected, examined by direct microscopy and inoculated for culture study. The demographic features and possible risk factors were recorded and assessed by logistic regression models.
  
  
  RESULTS
  We clinically diagnosed onychomycosis in 152 out of 8,122 (0.18%) school children. DLSO was the most frequent clinical diagnosis (120/152, 78.9%). Culture-positive onychomycosis was detected in 27/152 (17.7%) children. The prevalence of culture-positive onychomycosis was determined as 0.33%. All culture-positive samples were only from toenails. The onychomycosis causative agents were dermatophytes in 17/27 cases (62.9%), including Trichophyton rubrum 12 (44.4%), Trichophyton mentagrophytes 1 (3.7%), Trichophyton tonsurans 1 (3.7%) and Trichophyton spp. 3 (11.1%) and yeasts in 10/27 cases (37.1%), including Candida glabrata 4 (14.8%), Candida parapsilosis 1 (3.7%), Trichosporon 2 (7.4%) and Rhodotorula 3 (11.1%). Age, father's occupation, number of siblings and rooms were statistically associated with the frequency of onychomycosis.
  
  
  CONCLUSIONS
  Although to be prevalence of onychomycosis in school children in central Anatolia of Turkey seems very low degree, pediatric onychomycosis is a growing public health concern all over the world. Children having more siblings or unemployed fathers and children living in small house as well as older children should be examined carefully for onychomycosis.
authors.affiliation: Department of Pediatrics, Gulhane Military Medical Faculty, Ankara, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Gulgun
authors.forename: Elcin
authors.initials: E
authors.lastname: Balci
authors.forename: Abdulbaki
authors.initials: A
authors.lastname: Karaoglu
authors.forename: Vural
authors.initials: V
authors.lastname: Kesik
authors.forename: Oguzhan
authors.initials: O
authors.lastname: Babacan
authors.forename: Muzaffer Kursat
authors.initials: MK
authors.lastname: Fidanci
authors.forename: Turker
authors.initials: T
authors.lastname: Turker
authors.forename: Duran
authors.initials: D
authors.lastname: Tok
authors.forename: Nedret
authors.initials: N
authors.lastname: Koc
mesh_terms: D000293:Adolescent; D002176:Candida albicans / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005533:Foot Dermatoses / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D008297:Male; D014009:Onychomycosis / Q000175:diagnosis / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D012424:Rural Population / Q000639:trends; D013334:Students; D014421:Turkey / Q000453:epidemiology; D014505:Urban Population / Q000639:trends