title: Cancer in pregnancy: a 10-year experience in shahid sadoughi hospital, yazd, iran.
abstract: BACKGROUND
  Although occurrence of cancer during pregnancy is rare, it leads to high morbidity and mortality in both mother and fetus. Recent trends in prolongation of child-bearing age have made cancer-associated pregnancies more frequent than past. As yet there are few documents concerning cancer and its related treatment outcomes during pregnancy. This study aimed at describing clinical characteristics of pregnant women with cancer in the Shahid Sadoughi hospital in Yazd, Iran.
  
  
  METHODS
  Case series were reviewed retrospectively, which included 19 pregnant women diagnosed with cancer in Shahid Sadoughi hospital from 2002 to 2012. Data collected comprised demographics, pregnancy characteristics and outcomes, type of cancer, clinical stage, treatment and oncological.
  
  
  RESULTS
  From 17 pregnant women with cancer, 4 women had gynecologic cancers and 13 had non-gynecologic cancers. The Following tumors were observed: breast [6], acute myeloblastic leukemia [3], uterine cervix carcinoma [3], ovary [1], chronic myelogenous leukemia [1], lymphoma [1], papillary carcinoma of thyroid [1], and pseudopapillary carcinoma of pancreas [1]. The mean age of patients was 30.6 years, and the mean gestational age at diagnosis was 21.1 weeks. Surgical treatment was performed in 3 patients, 6 patients were treated by chemotherapy, and in 3 by both.
  
  
  CONCLUSIONS
  Although cancer during pregnancy is uncommon, it is considered an important problem due to unsuitable maternal and fetal outcomes and lack of standard management guidelines. Our cases represent examples of feasible or justifiable managements for them.
authors.affiliation: Department of Gynecological Oncology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran;
authors.forename: M
authors.initials: M
authors.lastname: Karimi-Zarchi
authors.forename: M Ghane
authors.initials: MG
authors.lastname: Ezabadi
authors.forename: S
authors.initials: S
authors.lastname: Hekmatimoghaddam
authors.forename: M
authors.initials: M
authors.lastname: Mortazavizade
authors.forename: S
authors.initials: S
authors.lastname: Taghipour
authors.forename: M
authors.initials: M
authors.lastname: Vahidfar
authors.forename: H
authors.initials: H
authors.lastname: Vahedian
authors.forename: M
authors.initials: M
authors.lastname: Forat
authors.forename: F
authors.initials: F
authors.lastname: Shamsi
authors.forename: A
authors.initials: A
authors.lastname: Miratashi-Yazdi
keywords: Yazd; cancer; diagnosis; management; outcome; pregnancy; treatment