title: Outcome from spontaneous subarachnoid haemorrhage--results from 2007-2011 and comparison with our previous series.
abstract: OBJECTIVE
  The management of patients with spontaneous subarachnoid haemorrhage (SAH) has changed, in part due to interventions now being extended to patients who are older and in a worse clinical condition. This study evaluates the effects of these changes on a complete 5-year patient material.
  
  
  METHODS
  Demographic data and results from 615 patients with SAH admitted from 2007 to 2011 were put together. Aneurysms were found in 448 patients (72.8%). They were compared with the aneurysm group (n = 676) from a previously published series from our centre (2001-2006). Linear regression was used to determine variables predicting functional outcome in the whole aneurysm group (2001-2011).
  
  
  RESULTS
  Patients in the more recent aneurysm group were older, and they were in a worse clinical condition on admission. Regarding younger patients admitted in World Federation of Neurosurgical Societies SAH grading (WFNS) 3, there were fewer with a good outcome. In the whole aneurysm group 2001-2011, outcome was best predicted by age, clinical condition at admission, and the size of the bleeding, and not by treatment mode or localization of aneurysm.
  
  
  CONCLUSIONS
  It seems important for the outcome that aneurysms are treated early. The clinical course after that depends largely on the condition of the patient on admission rather than on aneurysm treatment method. This, together with the fact that older patients and those in worse condition are now being admitted, increases demands on neurointensive care. Further improvement in patient outcome depends on better understanding of acute brain injury mechanisms and improved neurointensive care as well as rehabilitation measures.
authors.affiliation: Department of Neuroscience, Neurosurgery, Uppsala University, University Hospital , 751 85 Uppsala , Sweden.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Ronne-Engström
authors.forename: Ljubisa
authors.initials: L
authors.lastname: Borota
authors.forename: Raj
authors.initials: R
authors.lastname: Kothimbakam
authors.forename: Niklas
authors.initials: N
authors.lastname: Marklund
authors.forename: Anders
authors.initials: A
authors.lastname: Lewén
authors.forename: Per
authors.initials: P
authors.lastname: Enblad
mesh_terms: D000368:Aged; D000792:Angiography / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013345:Subarachnoid Hemorrhage / Q000503:physiopathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome