title: In vivo Noninvasive Small Animal Molecular Imaging.
abstract: The remarkable efforts that are made on molecular imaging technologies demonstrate its potential importance and range of applications. The generation of disease-specific animal models, and the developments of target-specific probes and genetically encoded reporters are another important component. Continued improvements in the instrumentation, the identification of novel targets and genes, and the availability of improved imaging probes should be made. Multimodal imaging probes should provide easier transitions between laboratory studies, including small animal studies and clinical applications. Here, we reviewed basic strategies of noninvasive in vivo imaging methods in small animals to introducing the concept of molecular imaging.
authors.affiliation: Department of Nuclear Medicine, Cancer Imaging Center, Seoul National University Cancer Hospital, Seoul, Korea ; Laboratory of Molecular Imaging and Therapy, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Hyewon
authors.initials: H
authors.lastname: Youn
authors.forename: Kee-Jong
authors.initials: KJ
authors.lastname: Hong
keywords: animal imaging; computed tomography; magnetic resonance imaging; nuclear imaging; optical imaging; ultrasonography