title: Synthesis of solid 2-pyridylzinc reagents and their application in Negishi reactions.
abstract: In search of alternatives to unstable or unreliable 2-pyridylboron reagents, we have explored two new varieties of solid, moderately air-stable 2-pyridylzinc reagents. Both reagents can be manipulated in air and are competent nucleophiles in Negishi cross-coupling reactions.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology , 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States, and Department Chemie, Ludwig-Maximilians-Universität München , Butenandtstr. 5-13, 81377 München, Germany.
authors.forename: James R
authors.initials: JR
authors.lastname: Colombe
authors.forename: Sebastian
authors.initials: S
authors.lastname: Bernhardt
authors.forename: Christos
authors.initials: C
authors.lastname: Stathakis
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Buchwald
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel
mesh_terms: D002384:Catalysis; D007202:Indicators and Reagents / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D007202:Indicators and Reagents; D011725:Pyridines; D015032:Zinc