title: Age Predicts Functional Outcome in Acute Stroke Patients with rt-PA Treatment.
abstract: The standard treatment for acute ischemic stroke is thrombolytic therapy. There is limited data on prognostic factors of acute stroke with thrombolytic therapy particularly in Asian population. Acute ischemic stroke patients who were treated with thrombolytic therapy at Srinagarind Hospital between May 2008 and July 2010 were included. Factors associated with Barthel index more than 80 were studied by multiple logistic regression analysis. There were 75 patients included in the study. The mean NIHSS scores before treatment and at 3 months were 9.16 ± 4.82 and 3.83 ± 4.00, respectively, and median Barthel index at 3 months was 86. Only significant predictor for having Barthel index more than 80 points at 3 months was age (adjusted odds ratio 0.929, 95% confidence interval 0.874, 0.988). Four patients developed intracranial hemorrhage after the treatment (5%), and two died (2.6%). In conclusion, age predicts Barthel index in acute stroke patients with rt-PA treatment.
authors.affiliation: Department of Medicine, Faculty of Medicine, Khon Kaen University, 123 Mitraparp Road, Khon Kaen 40002, Thailand.
authors.forename: Jarin
authors.initials: J
authors.lastname: Chindaprasirt
authors.forename: Kittisak
authors.initials: K
authors.lastname: Sawanyawisuth
authors.forename: Paiboon
authors.initials: P
authors.lastname: Chattakul
authors.forename: Panita
authors.initials: P
authors.lastname: Limpawattana
authors.forename: Somsak
authors.initials: S
authors.lastname: Tiamkao
authors.forename: Patcharin
authors.initials: P
authors.lastname: Aountri
authors.forename: Verajit
authors.initials: V
authors.lastname: Chotmongkol