title: [A case of pleomorphic liposarcoma in a patient with Crohn's disease taking azathioprine].
abstract: Azathioprine is frequently used for the treatment of inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis. Lymphomas, squamous cell carcinomas, and undifferentiated pleomorphic sarcomas have been reported among patients receiving azathioprine therapy. Herein, we report a case of pleomorphic liposarcoma of chest wall which occurred in a 44-year-old man with Crohn's disease taking azathioprine. He was diagnosed with Crohn's disease 3 years ago after suffering from abdominal pain and hematochezia for 12 years. He had been taking 50 mg of azathioprine per day for 23 months when he visited the thoracic and cardiovascular surgery clinic due to right chest palpable mass that had rapidly grown during the past 2 months. Excisional biopsy was performed and the mass was diagnosed as pleomorphic liposarcoma. Therefore, he underwent radical excision of the right chest wall mass, which measured 11.0 × 6.5 cm in size. He is scheduled to receive radiation therapy and chemotherapy.
authors.affiliation: Departments of Internal Medicine, Thoracic and Cardiovascular Surgery and Pathology, National Police Hospital, Seoul, Korea.
authors.forename: Soo Min
authors.initials: SM
authors.lastname: Ahn
authors.forename: Seong O
authors.initials: SO
authors.lastname: Suh
authors.forename: Yu Mi
authors.initials: YM
authors.lastname: Oh
authors.forename: Chang Yong
authors.initials: CY
authors.lastname: Yun
authors.forename: Hyoung Hun
authors.initials: HH
authors.lastname: Sim
authors.forename: Chae A
authors.initials: CA
authors.lastname: Park
authors.forename: Cheol Min
authors.initials: CM
authors.lastname: Song
authors.forename: Ji Yoon
authors.initials: JY
authors.lastname: Bae
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use*; D003113:Colonoscopy; D003131:Combined Modality Therapy; D003424:Crohn Disease / Q000150:complications / Q000188:drug therapy*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008080:Liposarcoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D008297:Male; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D007166:Immunosuppressive Agents; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D001379:Azathioprine