title: HbA1c as a Diagnostic Test for Diabetes Mellitus - Reviewing the Evidence.
abstract: The evidence base in support of HbA1c as a diagnostic test for diabetes mellitus is focused on predicting a clinical outcome, considered to be the pinnacle of the Stockholm Hierarchy applied to reference intervals and clinical decision limits. In the case of diabetes, the major outcome of interest is the long term microvascular complications for which a large body of data has been accumulated, leading to the endorsement of HbA1c for diagnosis in many countries worldwide, with some variations in cut-offs and testing strategies.
authors.affiliation: Canterbury Health Laboratories, PO Box 151, Christchurch, New Zealand.
authors.forename: Chris
authors.initials: C
authors.lastname: Florkowski