title: Transdermal scopolamine in the management of postparotidectomy salivary fistula.
abstract: Parotid fistula represents an uncommon complication in parotid surgery. Its early recognition contributes to successful management. The condition is distressing for both the patient and the surgeon, since conservative and operative treatment frequently fail. There is no consensus on the optimal management of parotid gland fistula. The aim of this study is to describe a new, simple procedure in the treatment of this condition using transdermal scopolamine. We report 3 cases of salivary fistulae occurring after parotidectomy. The patients were admitted to our department with swelling in the parotid region and an output of clear drainage from the drain site during oral intake. The patients were treated with a scopolamine transdermal release system applied to hairless skin overlying the parotid region. A prompt and remarkable decrease in daily salivary output was observed. Fistulae healed completely within 3 days. No collateral effects were observed. Parotid fistulae do not generally occur as a complication of parotidectomies. Their management can be difficult, and several methods of treatment have been attempted. We believe that the use of transdermal scopolamine is a valid option in the treatment of parotid fistulae without causing collateral effects.
authors.affiliation: Department of Otorhinolaryngology, "Sapienza" University of Rome, Via Adolfo Venturi 19, 00162 Rome, Italy. andrea.gallo@uniroma1.it.
authors.forename: Andrea
authors.initials: A
authors.lastname: Gallo
authors.forename: Valentina
authors.initials: V
authors.lastname: Manciocco
authors.forename: Giulio
authors.initials: G
authors.lastname: Pagliuca
authors.forename: Salvatore
authors.initials: S
authors.lastname: Martellucci
authors.forename: Marco
authors.initials: M
authors.lastname: de Vincentiis
mesh_terms: D000279:Administration, Cutaneous; D017577:Cutaneous Fistula / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018727:Muscarinic Antagonists / Q000627:therapeutic use*; D010307:Parotid Neoplasms / Q000601:surgery*; D011183:Postoperative Complications / Q000188:drug therapy* / Q000209:etiology; D012467:Salivary Gland Fistula / Q000188:drug therapy* / Q000209:etiology; D012601:Scopolamine / Q000627:therapeutic use*
chemical_list: D018727:Muscarinic Antagonists; D012601:Scopolamine