title: Intense splenic 99mTc-MDP uptake in a patient with myelofibrosis.
abstract: 99mTc-MDP bone scan was performed in a 49-year-old woman with breast cancer. Whole-body bone scan showed multiple foci of increased MDP activity in the bone and intense splenic 99mTc-MDP uptake. Initial bone marrow aspiration in multiple locations yielded no blood cells. A subsequent bone marrow biopsy in the left anterior superior iliac spine showed myelofibrosis in addition to the known bone metastasis.
authors.affiliation: From the *Department of Nuclear Medicine, the First Hospital of Lanzhou University, Lanzhou; and †Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Beijing, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Chen
authors.forename: Chun
authors.initials: C
authors.lastname: Liu
authors.forename: Jigang
authors.initials: J
authors.lastname: Yang
mesh_terms: D001692:Biological Transport; D005260:Female; D006801:Humans; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000000981:diagnostic imaging* / Q000378:metabolism*; D011877:Radionuclide Imaging; D013154:Spleen / Q000000981:diagnostic imaging / Q000378:metabolism*; D013669:Technetium Tc 99m Medronate / Q000378:metabolism*
chemical_list: D013669:Technetium Tc 99m Medronate