title: Management of postoperative instrumented spinal wound infection.
abstract: BACKGROUND
  Wound infection following spinal instrumented surgery is a frequent complication. The optimal treatment of acute deep wound infection following spinal instrumentation fusion remains controversial because of variability in cohort identification, definition of an infection, and the instrument used to measure outcomes. This retrospective study evaluated the clinical curative effect for postoperative spinal infection after instrumented spine fusion with extensive debridement, or implant removal.
  
  
  METHODS
  From January 2004 to October 2009, 851 patients were identified who underwent surgical treatment of spinal diseases. The medical records of patients who developed infections were reviewed in detail.
  
  
  RESULTS
  Of 851 patients, 41 (4.9%) developed an infection. Thirty-three were acute, and eight were delayed. Acute infected cases were managed with antibiotic therapy, and aggressive debridement of the wound and soft tissues leaving all instrumentation in situ in all but one patient. The most common symptoms of acute infection included: posterior incisional drainage (26 of 33 patients), back pain (22 of 33 patients) and fever (13 of 33 patients). Among patients with delayed onset infection, five of eight patients had local pain, four of eight patients had incision drainage, and one patient had a prolonged period of intermittent fever. The most frequent causative organism for postoperative spinal infection following spine surgery is Staphylococcus aureus. Pseudarthrosis was noted in long-term follow-up in four of 41 patients.
  
  
  CONCLUSIONS
  We recommend irrigation and debridement, no instrumentation removal, and, if necessary, repeat debridement followed by delayed primary closure for the treatment of acute deep infection with instrumentation.
authors.affiliation: Department of Orthopaedics, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China (Email: fangxiutong@163.com).
authors.forename: Xiu-tong
authors.initials: XT
authors.lastname: Fang
authors.forename: Kirkham B
authors.initials: KB
authors.lastname: Wood
mesh_terms: D003646:Debridement; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000175:diagnosis* / Q000188:drug therapy / Q000517:prevention & control / Q000601:surgery*