title: Iron oxide-loaded hollow mesoporous silica nanocapsules for controlled drug release and hyperthermia.
abstract: Magnetic field-responsive iron oxide-loaded hollow mesoporous silica nanocapsules that exhibit high drug loading capacity were synthesized using polymer nanospheres as sacrificial templates. Due to their magnetic field induced heating and remotely triggered drug release capabilities, these hybrid nanomaterials provide an excellent platform for the combination of hyperthermia and chemotherapy.
authors.affiliation: Department of Chemistry, Case Western Reserve University, 10900 Euclid Ave., Cleveland, OH 44106, USA. anna.samia@case.edu.
authors.forename: Feng
authors.initials: F
authors.lastname: Lu
authors.forename: Adriana
authors.initials: A
authors.lastname: Popa
authors.forename: Shiwei
authors.initials: S
authors.lastname: Zhou
authors.forename: Jun-Jie
authors.initials: JJ
authors.lastname: Zhu
authors.forename: Anna Cristina S
authors.initials: AC
authors.lastname: Samia
mesh_terms: D004317:Doxorubicin / Q000008:administration & dosage / Q000737:chemistry / Q000378:metabolism; D005290:Ferric Compounds / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006979:Hyperthermia, Induced; D060526:Magnetic Fields; D053769:Nanocapsules / Q000737:chemistry*; D009369:Neoplasms / Q000188:drug therapy; D011108:Polymers / Q000737:chemistry; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*; D013696:Temperature
chemical_list: D005290:Ferric Compounds; D053769:Nanocapsules; D011108:Polymers; C000499:ferric oxide; D012822:Silicon Dioxide; D004317:Doxorubicin