title: The clinical research office of the endourological society ureteroscopy global study: indications, complications, and outcomes in 11,885 patients.
abstract: OBJECTIVE
  To assess the current indications for ureteroscopy (URS) treatment, outcome in terms of stone-free rate, and intra- and postoperative complications using the modified Clavien grading system.
  
  
  METHODS
  The Clinical Research Office of the Endourological Society collected prospective data as part of the URS Global Study for consecutive patients treated with URS at centers around the world for 1 year. URS was performed according to study protocol and local clinical practice guidelines. The stone size and location were recorded and postoperative outcome and complications, graded according to the modified Clavien grading system, reported.
  
  
  RESULTS
  Between January 2010 and October 2012, 11,885 patients received URS at 114 centers in 32 countries; 1852 had only renal stones, 8676 had only ureteral stones, and 1145 patients had both types of stone. Fragmentation was performed principally using a laser device (49.0%) or a pneumatic device (30.3%); no device was used in 17.9% of the patients. A high stone-free rate (85.6%) was achieved. The large majority of patients did not receive any further treatment for renal or ureter stones (89.4%). The postoperative complication rate was low (3.5%). The most frequent complication was fever (1.8%); a blood transfusion was required in 0.2% of patients. The majority of complications were Clavien grade I or II (2.8% of patients).
  
  
  CONCLUSIONS
  URS is an established minimal invasive treatment for urinary stones with a high success rate and low morbidity. Recent advances have expanded the indication for urinary stones, which now ranges from treatment of smaller sized distal ureter stones by semirigid URS to larger sized renal pelvis stones treated by flexible URS.
authors.affiliation: 1 Department of Urology, AMC University Hospital , Amsterdam, The Netherlands .
authors.forename: Jean
authors.initials: J
authors.lastname: de la Rosette
authors.forename: John
authors.initials: J
authors.lastname: Denstedt
authors.forename: Petrisor
authors.initials: P
authors.lastname: Geavlete
authors.forename: Francis
authors.initials: F
authors.lastname: Keeley
authors.forename: Tadashi
authors.initials: T
authors.lastname: Matsuda
authors.forename: Margaret
authors.initials: M
authors.lastname: Pearle
authors.forename: Glenn
authors.initials: G
authors.lastname: Preminger
authors.forename: Olivier
authors.initials: O
authors.lastname: Traxer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D035843:Biomedical Research; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007390:International Agencies; D007669:Kidney Calculi / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*; D011184:Postoperative Period; D011446:Prospective Studies; D012955:Societies, Medical; D016896:Treatment Outcome; D014514:Ureteral Calculi / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D018666:Ureteroscopy / Q000009:adverse effects*; D055815:Young Adult