title: Pregnancy outcome of five patients with renal amyloidosis regarding familial Mediterranean fever.
abstract: Familial Mediterranean fever (FMF) is an autosomal recessive disease affecting mainly patients of the Mediterranean basin and its major complication is the development of renal AA amyloidosis. On the other hand pregnancy with amyloidosis is not common; nevertheless, amyloidosis will complicate pregnancies also with the underlying disease and may cause terrible perinatal morbidities and mortalities. We report here the cases of five pregnant women and their pregnancy outcomes, who have been diagnosed with FMF complicated by renal amyloidosis. In the five cases, we observed that increased pregnancy complication such as small for gestational age, intrauterine growth restriction, preeclampsia and preterm birth.
authors.affiliation: Department of Obstetrics and Gynecology, Maternal Fetal Medicine Unit, School of Medicine, Hacettepe University , Ankara , Turkey.
authors.forename: Mert
authors.initials: M
authors.lastname: Turgal
authors.forename: Ilker
authors.initials: I
authors.lastname: Selcuk
authors.forename: Ozgur
authors.initials: O
authors.lastname: Ozyuncu
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000150:complications* / Q000209:etiology; D003078:Colchicine / Q000627:therapeutic use; D010505:Familial Mediterranean Fever / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000150:complications* / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D050257:Tubulin Modulators / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D050257:Tubulin Modulators; D003078:Colchicine