title: Clinical features and outcomes of vitrectomy in pediatric ocular injuries-eye injury vitrectomy study.
abstract: BACKGROUND
  Severe pediatric ocular injury remains a frequent and difficult problem. Vitrectomy is a major technique that has been used to manage severely damaged eyes. However, limited follow-up studies exist currently.
  
  
  OBJECTIVE
  To evaluate the clinical features and predictive factors of visual and anatomic outcomes in Eye Injury Vitrectomy Study (EIVS).
  
  
  METHODS
  Retrospective, consecutive, interventional case series.
  
  
  METHODS
  Reviewing and analyzing records of children, aged 15 years or younger, who had undergone vitrectomy for eye injuries in EIVS database between January 1997 and December 2009.
  
  
  METHODS
  Descriptive analyses and multiple Logistic regressions were employed for all variables using SPSS software (version 17.0, SPSS Inc.).
  
  
  RESULTS
  Eighty-seven children (89 eyes) with more than 6 months follow-up and complete records identified in EIVS were included in this study. Average follow-up was 12.7 months. The mean age was 9.4 ± 3.8 years. Seventy-seven eyes (86.5%) had open globe injuries, and 12 (13.5%) had closed globe injuries. Seventeen eyes (19.3%) presented with endophthalmitis. Seventy-five eyes (88.2%) presented with visual acuity of 4/200 or worse; however, 42 eyes (47.7%) achieved 4/200 or better vision with anatomical restoration after vitrectomy. Multiple analysis showed that choroidal damage, large scleral wound, and endophthalmitis were significantly associated with unfavorable outcome, the OR values were 16.7 (95% CI: 2.7-102.4, P = 0.002), 10.9 (95% CI: 1.7-71.6, P = 0.013), and 6.6 (95% CI: 1.0-42.4, P = 0.048), respectively.
  
  
  CONCLUSIONS
  Vitrectomy intervention resulted in favorable visual and anatomic outcomes in almost half of the injured eyes. Choroidal damage, large scleral wound, and endophthalmitis were the prognostic indicators of unfavorable outcome.
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Feng
authors.forename: Kang
authors.initials: K
authors.lastname: Feng
authors.forename: Yuntao
authors.initials: Y
authors.lastname: Hu
authors.affiliation: Department of Ophthalmology, Peking University Third Hospital, Ministry of Education's Key Laboratory of Vision Loss and Restoration, Beijing, China.
authors.forename: Zhizhong
authors.initials: Z
authors.lastname: Ma
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005129:Eye Foreign Bodies / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D015807:Eye Injuries, Penetrating / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D015599:Trauma Severity Indices; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*