title: Regioselective synthesis of oxepinones and azepinones by gold-catalyzed cycloisomerization of functionalyzed cyclopropyl alkynes.
abstract: A regioselective synthesis of oxepinones and azepinones in good to excellent yields from alkynylcyclopropanecarboxylic acid derivatives is described. This novel cycloisomerization cascade process consists of a nucleophilic addition followed by a cyclopropane ring-opening, where both donor and acceptor groups are required as substituents of the cyclopropane ring.
authors.affiliation: Instituto Universitario de Química Organometálica "Enrique Moles", Departamento de Química Orgánica e Inorgánica, Universidad de Oviedo, C/Julián Clavería, 8, 33006, Oviedo, Spain. eah@uniovi.es.
authors.forename: Jesús M
authors.initials: JM
authors.lastname: Fernández-García
authors.forename: Patricia
authors.initials: P
authors.lastname: García-García
authors.forename: Manuel A
authors.initials: MA
authors.lastname: Fernández-Rodríguez
authors.forename: Alexandra
authors.initials: A
authors.lastname: Pérez-Anes
authors.forename: Enrique
authors.initials: E
authors.lastname: Aguilar