title: Braking BRAF: AMPK leaves ERK stranded in the desert.
abstract: In this issue, Shen et al. (2013) show that BRAF phosphorylation by AMPK attenuates BRAF signaling and inhibits cell proliferation. This identifies BRAF as a novel AMPK substrate and further reveals how these pathways interact.
authors.affiliation: The CRUK Manchester Institute, University of Manchester, Manchester M20 4BX, UK.
authors.forename: Matthew
authors.initials: M
authors.lastname: Martin
authors.forename: Richard
authors.initials: R
authors.lastname: Marais
mesh_terms: D055372:AMP-Activated Protein Kinases / Q000378:metabolism*; D000818:Animals; D049109:Cell Proliferation; D005260:Female; D006801:Humans; D011494:Protein Kinases / Q000378:metabolism*; D048493:Proto-Oncogene Proteins B-raf / Q000378:metabolism*
chemical_list: D011494:Protein Kinases; C097199:KSR-1 protein kinase; D048493:Proto-Oncogene Proteins B-raf; D055372:AMP-Activated Protein Kinases