title: Brain abscess in a rhesus macaque (Macaca mulatta) with a cephalic implant.
abstract: We report a case of brain abscess after craniotomy and the placement of a recording chamber for electrophysiologic records in an adult rhesus macaque (Macaca mulatta) enrolled in visual research. Approximately 2 wk after surgery, the macaque presented with nonspecific gastrointestinal signs and showed no evidence of fever, neurologic deficits, increased intracranial pressure, suggestive alterations in the CBC, or abnormal changes in the recording chamber. The macaque responded to symptomatic and antibiotic treatment and showed no behavioral or abnormal clinical signs for 3 wk before collapsing suddenly. The macaque was euthanized, and pathologic evaluation revealed a large brain abscess immediately under the original craniotomy.
authors.affiliation: Animal Resources Department, The Salk Institute for Biological Studies, La Jolla, California, USA. mleblanc@salk.edu.
authors.forename: Mathias
authors.initials: M
authors.lastname: Leblanc
authors.forename: Kristy
authors.initials: K
authors.lastname: Berry
authors.forename: Holly
authors.initials: H
authors.lastname: McCort
authors.forename: Jon D
authors.initials: JD
authors.lastname: Reuter
mesh_terms: D000818:Animals; D001921:Brain / Q000382:microbiology / Q000473:pathology; D001922:Brain Abscess / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D003399:Craniotomy / Q000009:adverse effects / Q000662:veterinary*; D020007:Implants, Experimental / Q000009:adverse effects* / Q000382:microbiology; D008253:Macaca mulatta; D008992:Monkey Diseases / Q000382:microbiology / Q000473:pathology*