title: Tula hantavirus infection in immunocompromised host, Czech Republic.
abstract: We report molecular evidence of Tula hantavirus as an etiologic agent of pulmonary-renal syndrome in an immunocompromised patient. Acute hantavirus infection was confirmed by using serologic and molecular methods. Sequencing revealed Tula virus genome RNA in the patient's blood. This case shows that Tula virus can cause serious disease in humans.
authors.forename: Hana
authors.initials: H
authors.lastname: Zelená
authors.forename: Jakub
authors.initials: J
authors.lastname: Mrázek
authors.forename: Tomáš
authors.initials: T
authors.lastname: Kuhn
mesh_terms: D000293:Adolescent; D000914:Antibodies, Viral / Q000276:immunology; D018153:Czech Republic; D016679:Genome, Viral; D005921:Glomerulonephritis / Q000175:diagnosis*; D006476:Orthohantavirus / Q000145:classification* / Q000235:genetics* / Q000276:immunology; D018778:Hantavirus Infections / Q000175:diagnosis*; D006470:Hemorrhage / Q000175:diagnosis*; D006801:Humans; D016867:Immunocompromised Host; D008171:Lung Diseases / Q000175:diagnosis*; D008297:Male; D008969:Molecular Sequence Data; D010802:Phylogeny; D012367:RNA, Viral
chemical_list: D000914:Antibodies, Viral; D012367:RNA, Viral
keywords: Tula virus; hantavirus; hantavirus pulmonary syndrome; hemorrhagic fever with renal syndrome; immunocompromised host; viruses