title: Comparative Study of Cytomorphological Robinson's Grading for Breast Carcinoma with Modified Bloom-Richardson Histopathological Grading.
abstract: Objective. To study the correlation of cytomorphological Robinson's grading for breast cancers with a modified Bloom-Richardson histopathological grading. Materials and Methods. One hundred sixteen cytologically malignant breast tumour cases were included in this study and correlated with paraffin embedded sections. Breast lumps were varied from less than 1 cm to 11 cm in greatest dimension. FNA was performed from different sites of the breast lump, and smears were stained with Giemsa and H&E stain and evaluated for cytological grading according to Robinson's grading system. Paraffin embedded tissue sections were stained with hematoxylin and eosin stain and graded according to modified Bloom-Richardson grading system. Comparison between these two grading systems was done. Results. Cytologically grade I, grade II, and grade III cases were 13.8%, 64.65%, and 21.55%, respectively. Histologically 25%, 54.31%, and 20.69% cases were grade I, grade II, and grade III, respectively. Concordance rate between cytology and histology of grade I, grade II, and grade III tumors was 75%, 70.67%, and 60% respectively. The absolute concordance rate was 68.97%. Conclusion. In the era of multiple treatment modalities and neoadjuvant therapy, cytological grading can be used as a prognostic factor for better management of patients.
authors.affiliation: Department of Pathology, D.D.U. Hospital, Harinagar, New Delhi 110066, India.
authors.forename: Neelam
authors.initials: N
authors.lastname: Sood
authors.forename: Jitendra Singh
authors.initials: JS
authors.lastname: Nigam
authors.forename: Poonam
authors.initials: P
authors.lastname: Yadav
authors.forename: Shivani
authors.initials: S
authors.lastname: Rewri
authors.forename: Ankit
authors.initials: A
authors.lastname: Sharma
authors.forename: Anita
authors.initials: A
authors.lastname: Omhare
authors.forename: Jaya
authors.initials: J
authors.lastname: Malhotra