title: Rh-catalyzed highly enantioselective hydroalkynylation reaction of norbornadiene derivatives.
abstract: The complexes of various Rh precusors with ferrocenyl chiral ligand (R,S)-Cy2PF-PPh2 were found effective catalysts for the asymmetric hydroalkynylation reaction of norbornadiene derivatives. When RhCl3·3H2O was employed, good yields (up to 98%) and high enantioselectivities (up to >99.9% ee) could be obtained for the reactions of a broad scope of substrates.
authors.affiliation: Key Laboratory of Chemistry in Ethnic Medicinal Resources, Yunnan University of Nationalities , Kunming, Yunnan, 650500, China.
authors.forename: Baomin
authors.initials: B
authors.lastname: Fan
authors.forename: Jianbin
authors.initials: J
authors.lastname: Xu
authors.forename: Qingjing
authors.initials: Q
authors.lastname: Yang
authors.forename: Sifeng
authors.initials: S
authors.lastname: Li
authors.forename: Hualei
authors.initials: H
authors.lastname: Chen
authors.forename: Shanshan
authors.initials: S
authors.lastname: Liu
authors.forename: Lu
authors.initials: L
authors.lastname: Yu
authors.forename: Yongyun
authors.initials: Y
authors.lastname: Zhou
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D008024:Ligands; D015394:Molecular Structure; D009636:Norbornanes / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D008024:Ligands; D009636:Norbornanes; D012238:Rhodium