title: Multiple liver abscess formation and primary gastrointestinal stromal tumor.
abstract: Gastrointestinal stromal tumors are the most common mesenchymal tumors of the gastrointestinal tract. The introduction of a number of small molecule tyrosine kinase inhibitors has revolutionized the management of metastatic disease. Surgery is the mainstay of management for localized disease. Patients with high risk tumors are treated with adjuvant imatinib. We report the rare presentation of a localized primary small bowel gastrointestinal stromal tumor in association with multiple liver abscesses. Cystic liver lesions should be fully evaluated in gastro intestinal tumor patients to exclude an infective cause. Treatment with intravenous antibiotics resulted in clinical and radiological improvement of the liver abscesses. The small bowel tumor was treated with surgical resection.
authors.affiliation: University of Washington Medical Center, Fred Hutchinson Cancer Research Center , Seattle, WA, USA.
authors.forename: Amy E
authors.initials: AE
authors.lastname: Chang
authors.forename: Gary N
authors.initials: GN
authors.lastname: Mann
authors.forename: Benjamin
authors.initials: B
authors.lastname: Hoch
authors.forename: Elizabeth T
authors.initials: ET
authors.lastname: Loggers
authors.forename: Seth M
authors.initials: SM
authors.lastname: Pollack
authors.forename: Orpheus
authors.initials: O
authors.lastname: Kolokythas
authors.forename: Robin L
authors.initials: RL
authors.lastname: Jones
keywords: gastrointestinal stromal tumor; imatinib; liver abscess; therapy