title: [Polymorphisms of 21 short tandem repeat loci of Salar minority ethnic group in Qinghai Province].
abstract: OBJECTIVE
  To investigate the polymorphisms of 21 short tandem repeat (STR)loci of Salar minority ethnic group in Qinghai Province.
  
  
  METHODS
  Blood samples were collected from 120 unrelated healthy Salar individuals from Gandu town in Hualong county. DNA templates were screened by home-made AGCU21+1 kit. The findings were further compared with those of Hans in Zhejiang Province, Hans in Ningxia Hui Autonomous Region, Tibetans in Tibet Autonomous Region, and Tujias in Hubei Province.
  
  
  RESULTS
  The allele frequencies of 21 STR loci ranged 0.0042-0.4917, the genotype frequencies ranged 0.0083-0.3750, the power of discrimination ranged 0.796-0.948, the heterozygosity ranged 0.650-0.817, the polymorphism information contents ranged 0.590-0.810, and the power of exclusion ranged 0.355-0.630. The cumulative coupling probability was 1.75×10(-20), and the cumulative power of exclusion was 0.9999999. Significant differences were found at 14, 12, 12, 13 of the 21 STR loci between Salar and Hans of Zhejiang Province, Ningxia Hui Autonomous Region, Tibetans of Tibet Autonomous Region, and Tujias of Hubei Province (P<0.05).
  
  
  CONCLUSIONS
  The 21 STR loci used in this study are highly polymorphic in Salar minority ethnic group from Qinghai Province and therefore suitable for population genetics study, screening of disease-related genes, and forensic individual identification.
authors.affiliation: Institute of Forensic Science of Changzhou, Changzhou, Jiangsu 213003, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Ma
authors.forename: Yan-bin
authors.initials: YB
authors.lastname: Wang
authors.forename: Kai
authors.initials: K
authors.lastname: Li
authors.forename: Jian-wen
authors.initials: JW
authors.lastname: Wang
mesh_terms: D044466:Asian People / Q000235:genetics*; D002681:China; D005006:Ethnicity / Q000235:genetics; D005838:Genotype; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D008913:Minority Groups; D011110:Polymorphism, Genetic