title: Rheumatic inflammatory eye diseases of childhood.
abstract: Chronic inflammatory eye diseases are a common manifestation of pediatric rheumatologic diseases, potentially leading to lifelong vision impairment and disability. The mechanisms leading to the breach of the blood eye/brain barrier and the subsequent immune attack against a variety of intraocular mostly unidentified antigens remains poorly understood. Pediatric rheumatologists need to be familiar with the various inflammatory eye diseases because they are often responsible for selecting and supervising treatment in close collaboration with the ophthalmologist. This article provides an update of recent developments in the pathogenesis and treatment of the most relevant ocular diseases encountered in rheumatologic practice.
authors.affiliation: Division of Rheumatology, Children's Hospital Los Angeles, Los Angeles, CA, USA. Electronic address: areiff@chla.usc.edu.
authors.forename: Andreas
authors.initials: A
authors.lastname: Reiff
authors.forename: Sibel
authors.initials: S
authors.lastname: Kadayifcilar
authors.forename: Seza
authors.initials: S
authors.lastname: Özen
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001528:Behcet Syndrome / Q000175:diagnosis / Q000188:drug therapy; D002648:Child; D055952:Cogan Syndrome / Q000175:diagnosis / Q000188:drug therapy; D005128:Eye Diseases / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D009395:Nephritis, Interstitial / Q000175:diagnosis / Q000188:drug therapy; D015868:Pars Planitis / Q000175:diagnosis / Q000188:drug therapy; D012216:Rheumatic Diseases / Q000175:diagnosis* / Q000188:drug therapy; D014605:Uveitis / Q000175:diagnosis* / Q000188:drug therapy; D014607:Uveomeningoencephalitic Syndrome / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D018501:Antirheumatic Agents; D007166:Immunosuppressive Agents
keywords: Blood eye/brain barrier; Inflammatory eye diseases; Ocular coherence tomography; Uveitis