title: Marine microorganisms as a source of bioactive agents.
abstract: Several ecological factors of the marine environment were used in developing a strategy for discovering useful bioactive agents from marine microorganisms. By consideration of sea water requirements, production and degradation of marine polymers, and plasmid content, several novel anti-malarial antibiotics, anti-tumor polysaccharides, glucan-degrading enzymes, and aminoglycoside antibiotics were found.
authors.affiliation: Institute of Microbial Chemistry, 3-14-23 Kamiosaki, Shinagawa-ku, 141, Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Okami