title: In vitro selection of peptide aptamers using a ribosome display for a conducting polymer.
abstract: Ribosome display was used to select peptide aptamers from a random library composed of hydrophilic amino acids for a conducting polymer, poly(3-hexylthiophene-2,5-diyl). Binding of aptamers was measured by quartz crystal microbalance, and the secondary structure of the peptide was investigated by circular dichroism.
authors.affiliation: Nano Medical Engineering Laboratory, RIKEN, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan; Emergent Bioengineering Materials Research Team, RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan; Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 1259 Nagatsuda, Midori-ku, Yokohama-shi, Kanagawa 226-8501, Japan.
authors.forename: Zha
authors.initials: Z
authors.lastname: Li
authors.affiliation: Nano Medical Engineering Laboratory, RIKEN, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan; Emergent Bioengineering Materials Research Team, RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan.
authors.forename: Takanori
authors.initials: T
authors.lastname: Uzawa
authors.affiliation: Responsive Organic Materials Laboratory, RIKEN, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan.
authors.forename: Haichao
authors.initials: H
authors.lastname: Zhao
authors.affiliation: Responsive Organic Materials Laboratory, RIKEN, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan.
authors.forename: Shyh-Chyang
authors.initials: SC
authors.lastname: Luo
authors.affiliation: Responsive Organic Materials Laboratory, RIKEN, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan.
authors.forename: Hsiao-hua
authors.initials: HH
authors.lastname: Yu
authors.affiliation: Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 1259 Nagatsuda, Midori-ku, Yokohama-shi, Kanagawa 226-8501, Japan.
authors.forename: Eiry
authors.initials: E
authors.lastname: Kobatake
authors.affiliation: Nano Medical Engineering Laboratory, RIKEN, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan; Emergent Bioengineering Materials Research Team, RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan; Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 1259 Nagatsuda, Midori-ku, Yokohama-shi, Kanagawa 226-8501, Japan. Electronic address: y-ito@riken.jp.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Ito
mesh_terms: D052158:Aptamers, Peptide / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism*; D002942:Circular Dichroism; D004553:Electric Conductivity; D019151:Peptide Library; D011108:Polymers / Q000737:chemistry* / Q000378:metabolism*; D011485:Protein Binding; D058525:Quartz Crystal Microbalance Techniques; D012270:Ribosomes / Q000378:metabolism*; D012666:Semiconductors; D013876:Thiophenes / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D052158:Aptamers, Peptide; D019151:Peptide Library; D011108:Polymers; D013876:Thiophenes; C000588862:poly(3-hexylthiophene-2,5-diyl)
keywords: Binding ability; In vitro selection; Peptide aptamer; Poly(3-hexylthiophene-2,5-diyl); Ribosome display