title: [Clinical application of a new titanium clip applier in transsphenoidal surgery].
abstract: OBJECTIVE
  To explore the efficacy and safety of a new titanium clip applier in transsphenoidal surgery for the A specially devised surgery instrument was developed and effectively applied in the management of intercavernous sinus hemorrhage and cerebrospinal fluid (CSF) leakage in transsphenoidal surgery.
  
  
  METHODS
  A total of 34 consecutive patients with pituiary adenoma underwent transsphenoidal surgery via a new deep pistol-shaped clip applier versus titanium clip. It was 21 cm long with a rectangular forepart. All patients were evaluated clinically and radiologically at 24 months and magnetic resonance imaging (MRI) was performed at Months 3-18 postoperation.
  
  
  RESULTS
  The application of such a new clip applier was effective. No operation was terminated due to ineffective hemorrhage, postoperative CSF leakage or related complications. Postoperative imaging studies revealed no significant evidence of clip artifact.
  
  
  CONCLUSIONS
  The technique of hemostasis and leakage clogging with such a new clip applier is safer, faster and more reliable than its conventional counterpart in achieving dural closure and intercavernous sinus hemostasis.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Hong
authors.forename: Si-yuan
authors.initials: SY
authors.lastname: Yin
authors.forename: Qun
authors.initials: Q
authors.lastname: Wu
authors.forename: Jun
authors.initials: J
authors.lastname: Yu
authors.forename: Jian-min
authors.initials: JM
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D002559:Cerebrospinal Fluid Rhinorrhea / Q000517:prevention & control; D004388:Dura Mater / Q000601:surgery; D004867:Equipment Design; D005260:Female; D006801:Humans; D007016:Hypophysectomy / Q000295:instrumentation* / Q000379:methods; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D013100:Sphenoid Bone / Q000601:surgery*; D013525:Surgical Instruments; D014025:Titanium
chemical_list: D014025:Titanium