title: False-positive rapid plasma reagin testing in patients with acute Plasmodium vivax malaria: a case control study.
abstract: Non-treponemal tests such as the rapid plasma reagin (RPR) assay are mainstays of syphilis diagnosis, but false-positive tests are common. We identified false-positive RPR titers in 8.2% of patients with malaria due to Plasmodium vivax in northern Peru. Similar rates were not detected in patients with other acute febrile illnesses.
authors.affiliation: United States Naval Medical Research Unit No. 6, Lima, Peru; Division of Infectious Diseases, Department of Internal Medicine, Naval Medical Center San Diego, San Diego, CA, United States. Electronic address: ryan.maves@med.navy.mil.
authors.forename: Ryan C
authors.initials: RC
authors.lastname: Maves
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Naval Medical Center San Diego, San Diego, CA, United States.
authors.forename: Katherine
authors.initials: K
authors.lastname: Dean
authors.affiliation: United States Naval Medical Research Unit No. 6, Lima, Peru.
authors.forename: Nilda
authors.initials: N
authors.lastname: Gadea
authors.affiliation: United States Naval Medical Research Unit No. 6, Lima, Peru.
authors.forename: Eric S
authors.initials: ES
authors.lastname: Halsey
authors.affiliation: United States Naval Medical Research Unit No. 6, Lima, Peru; Department of Laboratory Medicine, Naval Medical Center San Diego, San Diego, CA, United States.
authors.forename: Paul C F
authors.initials: PC
authors.lastname: Graf
authors.affiliation: United States Naval Medical Research Unit No. 6, Lima, Peru.
authors.forename: Andres G
authors.initials: AG
authors.lastname: Lescano
mesh_terms: D000208:Acute Disease; D000328:Adult; D016022:Case-Control Studies; D003710:Demography; D005189:False Positive Reactions; D005260:Female; D005335:Fever of Unknown Origin / Q000209:etiology*; D006801:Humans; D016780:Malaria, Vivax / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D010568:Peru; D010966:Plasmodium vivax / Q000302:isolation & purification*; D011935:Reagins / Q000097:blood*; D013587:Syphilis / Q000150:complications*; D013588:Syphilis Serodiagnosis; D013997:Time Factors; D055815:Young Adult
chemical_list: D011935:Reagins
keywords: Diagnostic test; Syphilis; Vivax malaria