title: Brønsted acid catalyzed and NIS-promoted cyclization of diynones: selective synthesis of 4-pyrone, 4-pyridone, and 3-pyrrolone derivatives.
abstract: Brønsted acid catalyzed tandem cyclization was found to be highly effective for the preparation of a series of polysubstituted 4-pyrones from diynones (yield up to 99%). 4-Pyridone and 3-pyrrolone derivatives were also selectively synthesized by employing NIS and/or Brønsted acid. NIS as an electrophilic reagent could promote these reactions efficiently and rapidly under very mild reaction conditions.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou 730000, People's Republic of China.
authors.forename: Yi-Feng
authors.initials: YF
authors.lastname: Qiu
authors.forename: Fang
authors.initials: F
authors.lastname: Yang
authors.forename: Zi-Hang
authors.initials: ZH
authors.lastname: Qiu
authors.forename: Mei-Jin
authors.initials: MJ
authors.lastname: Zhong
authors.forename: Li-Jing
authors.initials: LJ
authors.lastname: Wang
authors.forename: Yu-Ying
authors.initials: YY
authors.lastname: Ye
authors.forename: Bo
authors.initials: B
authors.lastname: Song
authors.forename: Yong-Min
authors.initials: YM
authors.lastname: Liang
mesh_terms: D000143:Acids / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D011728:Pyridones / Q000138:chemical synthesis* / Q000737:chemistry; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000143:Acids; D007659:Ketones; D011728:Pyridones; D011753:Pyrones; D011758:Pyrroles; C534143:4-pyridone