title: Device closure of a large atrial septal defect in a patient with severe pulmonary arterial hypertension after 1 year use of an oral endothelin receptor antagonist.
abstract: The presence of severe pulmonary arterial hypertension (PAH) in patients with atrial septal defect (ASD) is still thought to preclude shunt closure, although there are several reports of good clinical outcomes after vasodilator therapy. We report the case of a young woman with ASD and severe PAH who was able to successfully undergo percutaneous shunt closure following 1 year use of the oral endothelin receptor antagonist, bosentan.
authors.affiliation: Department of Internal Medicine, Sejong General Hospital, Bucheon, Korea.
authors.forename: In Hyun
authors.initials: IH
authors.lastname: Jung
authors.forename: Sang Yun
authors.initials: SY
authors.lastname: Lee
authors.forename: Sook Jin
authors.initials: SJ
authors.lastname: Lee
authors.forename: Joo Young
authors.initials: JY
authors.lastname: Lee
authors.forename: Nam Jin
authors.initials: NJ
authors.lastname: Park
authors.forename: Dea Sung
authors.initials: DS
authors.lastname: Ahn
authors.forename: Jae Hoon
authors.initials: JH
authors.lastname: Jung
authors.forename: Dong Hee
authors.initials: DH
authors.lastname: Shin
authors.forename: Dal Soo
authors.initials: DS
authors.lastname: Lim
keywords: Atrial septal defect; Pulmonary hypertension; Septal occlude device