title: Multiple allelic states of the cyh2 gene cause low- and high-level cycloheximide resistance in Saccharomyces cerevisiae.
abstract: At least four different mutations at the cyh2 locus (rp1X; gene product: YL24) of Saccharomyces cerevisiae confer cycloheximide resistance. The mutant YL24 proteins are either more basic (high-level resistant phenotype), more acidic (low-level resistant phenotype), or unchanged in their electrophoretic mobility (both low-and high-level resistant phenotypes). None of the mutations at other loci seem to induce high-level resistance to cycloheximide.
authors.affiliation: Lehrstuhl für Mikrobiologie der Universität, Maria-Ward-Str. 1a, 8000, München 19, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Stöcklein
authors.forename: A
authors.initials: A
authors.lastname: Jiménez
authors.forename: B
authors.initials: B
authors.lastname: Littlewood
authors.forename: W
authors.initials: W
authors.lastname: Piepersberg
authors.forename: J
authors.initials: J
authors.lastname: Davies