title: Anti-obesity effects of black ginseng extract in high fat diet-fed mice.
abstract: Black ginseng is produced by a repeated steaming process. The aim of this study was to investigate the anti-obesity effects of black ginseng ethanol extract (BG-EE) in high fat (HF) diet-fed mice. Two groups were fed either a normal control (NC) diet or a HF diet (45% kcal fat). The other three groups were given a HF diet supplemented with 1% BG-EE, 3% BG-EE, and 5% BG-EE for 12 wk. The anti-obesity effects of the BG-EE supplement on body weight, the development of fat mass, and lipid mechanisms were assessed in obese mice. HF-induced hyperlipidemia, fat accumulation in the liver, and white adipose tissues were reduced after BG-EE supplementation. Total fecal weight and the amount of fecal fat excretion also were increased after BG-EE supplementation. These results suggest that BG-EE may be useful to ameliorate HF-induced obesity through the strong inhibition of fat digestion.
authors.affiliation: Daedeok Bio Corporation Research and Development center, Daejeon 305-764, Korea.
authors.forename: Mi Ra
authors.initials: MR
authors.lastname: Lee
authors.forename: Byung Chan
authors.initials: BC
authors.lastname: Kim
authors.forename: Ran
authors.initials: R
authors.lastname: Kim
authors.forename: Hyun In
authors.initials: HI
authors.lastname: Oh
authors.forename: Hyun Kyoung
authors.initials: HK
authors.lastname: Kim
authors.forename: Kang Ju
authors.initials: KJ
authors.lastname: Choi
authors.forename: Chang Keun
authors.initials: CK
authors.lastname: Sung
keywords: Black ginseng; High fat diet; Hyperlipidemia; Obesity; Panax ginseng