title: Ovicidal effect of Piperaceae species on Biomphalaria glabrata, Schistosoma mansoni host.
abstract: Schistosomiasis is a neglected disease with public health importance in tropical and subtropical regions. An alternative to the disease control is the use of molluscicides to eliminate or reduce the intermediate host snail population causing a reduction of transmission in endemic regions. In this study nine extracts from eight Piperaceae species were evaluated against Biomphalaria glabrata embryos at blastula stage. The extracts were evaluated in concentrations ranging from 100 to 10 mg/L. Piper crassinervium and Piper tuberculatum extracts were the most active (100% of mortality at 20 mg/L and 30 mg/L respectively).
authors.affiliation: Instituto de Ciências Biomédicas, Universidade de São Paulo, São PauloSP, Brazil, ludmilanr@usp.br, ludmilanr@usp.br.
authors.forename: Ludmila Nakamura
authors.initials: LN
authors.lastname: Rapado
authors.forename: Priscila Orechio de Moraes
authors.initials: PO
authors.lastname: Lopes
authors.forename: Lydia Fumiko
authors.initials: LF
authors.lastname: Yamaguchi
authors.forename: Eliana
authors.initials: E
authors.lastname: Nakano
mesh_terms: D000818:Animals; D001700:Biomphalaria / Q000187:drug effects* / Q000469:parasitology; D004199:Disease Vectors; D008975:Molluscacides / Q000302:isolation & purification / Q000494:pharmacology*; D026321:Piperaceae / Q000737:chemistry* / Q000145:classification; D010936:Plant Extracts / Q000494:pharmacology*; D012555:Schistosomiasis mansoni
chemical_list: D008975:Molluscacides; D010936:Plant Extracts