title: Estimated fluoride doses from toothpastes should be based on total soluble fluoride.
abstract: The fluoride dose ingested by young children may be overestimated if based on levels of total fluoride (TF) rather than levels of bioavailable fluoride (total soluble fluoride-TSF) in toothpaste. The aim of the present study was to compare doses of fluoride intake based on TF and TSF. Fluoride intake in 158 Brazilian children aged three and four years was determined after tooth brushing with their usual toothpaste (either family toothpaste (n = 80) or children's toothpaste (n = 78)). The estimated dose (mg F/day/Kg of body weight) of TF or TSF ingested was calculated from the chemical analysis of the toothpastes. Although the ingested dose of TF from the family toothpastes was higher than that from the children's toothpastes (0.074 ± 0.007 and 0.039 ± 0.003 mg F/day/Kg, respectively; p < 0.05), no difference between types of toothpaste was found regarding the ingested dose based on TSF (0.039 ± 0.005 and 0.039 ± 0.005 mg F/day/Kg, respectively; p > 0.05). The fluoride dose ingested by children from toothpastes may be overestimated if based on the TF of the product. This finding suggests that the ingested dose should be calculated based on TSF. Dose of TSF ingested by children is similar whether family or children's toothpaste is used.
authors.affiliation: Department of Paediatric Dentistry and Orthodontics, School of Dentistry, Universidade Estadual de Montes Claros (UNIMONTES), Campus Darcy Ribeiro, Vila Mauricéia, Montes Claros, MG 39410-089, Brazil. carolcm10@hotmail.com.
authors.forename: Maria José L
authors.initials: MJ
authors.lastname: Oliveira
authors.forename: Carolina C
authors.initials: CC
authors.lastname: Martins
authors.forename: Saul M
authors.initials: SM
authors.lastname: Paiva
authors.forename: Livia M A
authors.initials: LM
authors.lastname: Tenuta
authors.forename: Jaime A
authors.initials: JA
authors.lastname: Cury
mesh_terms: D001938:Brazil; D002327:Cariostatic Agents / Q000032:analysis / Q000737:chemistry*; D002675:Child, Preschool; D005459:Fluorides / Q000032:analysis / Q000737:chemistry*; D006801:Humans; D017736:Ion-Selective Electrodes; D012995:Solubility; D014099:Toothbrushing; D014100:Toothpastes / Q000032:analysis / Q000737:chemistry*
chemical_list: D002327:Cariostatic Agents; D014100:Toothpastes; D005459:Fluorides