title: Toxic effects of penoxsulam herbicide in two fish species reared in southern Brazil.
abstract: Toxic effects of penoxsulam herbicide on acetylcholinesterase, thiobarbituric acid-reactive substances and protein carbonyl were studied in silver catfish (Rhamdia sp.) and carp (Cyprinus carpio). Acetylcholinesterase activity was inhibited in both brain and muscle tissue, with the inhibition being greater in carp than in silver catfish. The levels of malondialdehyde (MDA), an indicator of lipid peroxidation, decreased in silver catfish brain tissue, but increased in the carp brain. MDA also increased significantly in muscle tissue of silver catfish. The levels of protein carbonyl, another measure of oxidative damage, increased in the brain of both fish species, and in the muscle of carp. However, silver catfish exhibited a decrease in muscle protein carbonyl. It appears that silver catfish may possess better mechanisms of defense against penoxsulam toxicity than carp.
authors.affiliation: Chemistry Department, Federal University of Santa Maria, Santa Maria, RS, 97105-900, Brazil.
authors.forename: Camila Rebellatto
authors.initials: CR
authors.lastname: Murussi
authors.forename: Maria Luiza
authors.initials: ML
authors.lastname: Thorstenberg
authors.forename: Jossiele
authors.initials: J
authors.lastname: Leitemperger
authors.forename: Maiara
authors.initials: M
authors.lastname: Costa
authors.forename: Bárbara
authors.initials: B
authors.lastname: Clasen
authors.forename: Adriana
authors.initials: A
authors.lastname: Santi
authors.forename: Charlene
authors.initials: C
authors.lastname: Menezes
authors.forename: Vanessa Kruger
authors.initials: VK
authors.lastname: Engers
authors.forename: Vania Lucia
authors.initials: VL
authors.lastname: Loro
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000222:Adaptation, Physiological; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D001938:Brazil; D005399:Fishes / Q000378:metabolism*; D006540:Herbicides / Q000378:metabolism / Q000633:toxicity*; D015227:Lipid Peroxidation / Q000187:drug effects; D008315:Malondialdehyde / Q000378:metabolism; D013449:Sulfonamides / Q000378:metabolism / Q000633:toxicity*; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D014529:Uridine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000633:toxicity
chemical_list: D006540:Herbicides; D013449:Sulfonamides; D017392:Thiobarbituric Acid Reactive Substances; D008315:Malondialdehyde; C504402:penoxsulam; D000110:Acetylcholinesterase; D014529:Uridine