title: EQ-5D as a measure of programme outcome: results from the Singapore early psychosis intervention programme.
abstract: The current study aimed to establish the Health-Related Quality of Life (HRQoL) among participants with First Episode Psychosis (FEP) in Singapore, to elucidate the sociodemographic and clinical correlates of HRQoL, and ascertain the change after 1-year of treatment. Two hundred and forty one patients accepted into an Early Psychosis Intervention Programme (EPIP) from April 2009 to June 2011 and who had completed baseline EuroQol-5D (EQ-5D) assessments were included in this analysis. The mean (S.D.) EQ-5D index at baseline was 0.788 (0.258). One hundred thirty five (56.0%) patients who completed the EQ-5D assessment at the 12-month follow-up had a significantly higher EQ-5D index as compared to baseline. EQ-5D index was significantly higher among those patients who met criteria for remission at the 12-month interval than those who were not in remission. Our results suggest that the EQ-5D is responsive to improvement as it corresponded well to objective ratings of remission in our patients with FEP.
authors.affiliation: Research Division, Institute of Mental Health, Singapore. Electronic address: Mythily@imh.com.sg.
authors.forename: Mythily
authors.initials: M
authors.lastname: Subramaniam
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Edimansyah
authors.initials: E
authors.lastname: Abdin
authors.affiliation: Department of Early Psychosis Intervention, Institute of Mental Health, Singapore.
authors.forename: Lye Yin
authors.initials: LY
authors.lastname: Poon
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Janhavi Ajit
authors.initials: JA
authors.lastname: Vaingankar
authors.affiliation: Department of Early Psychosis Intervention, Institute of Mental Health, Singapore.
authors.forename: Helen
authors.initials: H
authors.lastname: Lee
authors.affiliation: Research Division, Institute of Mental Health, Singapore.
authors.forename: Siow Ann
authors.initials: SA
authors.lastname: Chong
authors.affiliation: Department of Early Psychosis Intervention, Institute of Mental Health, Singapore.
authors.forename: Swapna
authors.initials: S
authors.lastname: Verma
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care; D011618:Psychotic Disorders / Q000523:psychology / Q000628:therapy*; D011788:Quality of Life; D012559:Schizophrenia / Q000628:therapy*; D012565:Schizophrenic Psychology; D012846:Singapore; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D055815:Young Adult
keywords: Duration of untreated Psychosis; EQ-5D; Early psychosis; Remission; Singapore