title: Preparation of chiral bromomethylenecyclopropane and its use in Suzuki-Miyaura coupling: synthesis of the arylmethyl-(Z)-cyclopropane structure core.
abstract: A preparative method for an optically active bromomethylenecyclopropane unit and its practical conversion to (Z)-cyclopropane-containing chiral compounds via Suzuki-Miyaura coupling were established.
authors.affiliation: Faculty of Pharmaceutical Sciences and ‡Center for Research and Education on Drug Development, Hokkaido University , Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Tanabe
authors.forename: Mizuki
authors.initials: M
authors.lastname: Watanabe
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Hoshiya
authors.forename: Akira
authors.initials: A
authors.lastname: Mizuno
authors.forename: Hayato
authors.initials: H
authors.lastname: Fukuda
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Arisawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Shuto
mesh_terms: D003521:Cyclopropanes / Q000138:chemical synthesis* / Q000737:chemistry; D006842:Hydrocarbons, Brominated / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D003521:Cyclopropanes; D006842:Hydrocarbons, Brominated