title: Chemical-physical properties of experimental root canal sealers based on butyl ethylene glycol disalicylate and MTA.
abstract: OBJECTIVE
  The aim of this study was to evaluate the calcium release, pH, flow, solubility, water absorption, setting and working time of three experimental root canal sealers based on mineral trioxide aggregate (MTA) and two forms of calcium phosphates (CaP).
  
  
  METHODS
  The materials were composed of a base and a catalyst pastes mixed in a 1:1. The base paste was made by 60% bismuth oxide and 40% butyl ethylene glycol disalicylate. Three different catalyst pastes were formulated containing 60% MTA or 40% MTA+20% CaP (hydroxyapatite HA or dibasic calcium phosphate dehydrate DCPD), 39% Resimpol 8% and 1% titanium dioxide. MTA Fillapex was used as control. The release of calcium and hydroxyl ions, solubility and water absorption were measured on regular intervals for 28 days. The working time and flow were tested according to ISO 6876:2001 and the setting time according to ASTM C266. The data were analyzed using 1-way ANOVA with Tukey's test (p<.01).
  
  
  RESULTS
  All the cements showed basifying activity and released calcium ions. MTA Fillapex showed the highest values of flow (p<.01) and working/setting times (p<.01) and the smallest values of solubility (p<.01) and water absorption (p<.01).
  
  
  CONCLUSIONS
  All experimental materials showed satisfactory physical-chemical properties to be used as endodontic sealers in clinical practice.
authors.affiliation: Department of Restorative Dentistry, University of Campinas, Piracicaba, Brazil; Department of Odontostomatological Science, University of Bologna, Bologna, Italy. Electronic address: rafavitti@fop.unicamp.br.
authors.forename: Rafael P
authors.initials: RP
authors.lastname: Vitti
authors.forename: Carlo
authors.initials: C
authors.lastname: Prati
authors.forename: Mário Alexandre C
authors.initials: MA
authors.lastname: Sinhoreti
authors.forename: Cesar H
authors.initials: CH
authors.lastname: Zanchi
authors.forename: Manuela G
authors.initials: MG
authors.lastname: Souza E Silva
authors.forename: Fabrício A
authors.initials: FA
authors.lastname: Ogliari
authors.forename: Evandro
authors.initials: E
authors.lastname: Piva
authors.forename: Maria G
authors.initials: MG
authors.lastname: Gandolfi
mesh_terms: D017607:Aluminum Compounds / Q000737:chemistry*; D002118:Calcium / Q000737:chemistry; D017610:Calcium Compounds / Q000737:chemistry*; D004338:Drug Combinations; D005026:Ethylene Glycols / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D010087:Oxides / Q000737:chemistry*; D012387:Root Canal Filling Materials; D012459:Salicylates / Q000737:chemistry*; D017640:Silicates / Q000737:chemistry*; D012995:Solubility
chemical_list: C000601791:1,3-butyl ethylene glycol disalicylate; D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D005026:Ethylene Glycols; D010087:Oxides; D012387:Root Canal Filling Materials; D012459:Salicylates; D017640:Silicates; C086631:mineral trioxide aggregate; D002118:Calcium
keywords: Calcium release; Calcium-silicate cement; Endodontic sealer; Mineral trioxide aggregate (MTA); pH