title: Effect of maternal and infant vitamin D supplementation on vitamin D levels of breastfed infants.
abstract: The aim of our study was to investigate the effect of maternal vitamin D3 (400 U/day) supplementation on breastfed infants at 6 months of age. Mothers (n=96) were enrolled within 1 month after birth and assigned to the 400 IU/day regimen or no vitamin D3 supplementation for 6 months. All infants received 400 IU/day of vitamin D3 and were exclusively breastfed until 4 months of age. Of all mothers, 22.2% had vitamin D levels above 20 ng/ml initially. At the end of the study, vitamin D levels of mothers and their infants were similar in both groups. Thirteen percent of the infants in the intervention group and 20.5% in the control group had vitamin D levels below 12 ng/ml. Serum 25-hydroxyvitamin D (25(OH)D) concentrations at 6 months had increased significantly in mothers in the intervention group. Lactating mothers and their children need vitamin D supplementation but further studies are required with higher doses.
authors.affiliation: Department of Pediatrics, İstanbul Faculty of Medicine, İstanbul University, İstanbul, Turkey. esradevecioglu@gmail.com.
authors.forename: Fuat
authors.initials: F
authors.lastname: Buğrul
authors.forename: Esra
authors.initials: E
authors.lastname: Devecioğlu
authors.forename: Tülin
authors.initials: T
authors.lastname: Ozden
authors.forename: Gülbin
authors.initials: G
authors.lastname: Gökçay
authors.forename: Beyhan
authors.initials: B
authors.lastname: Omer
mesh_terms: D000328:Adult; D001942:Breast Feeding; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D015999:Multivariate Analysis; D011446:Prospective Studies; D013472:Sunlight; D014807:Vitamin D / Q000008:administration & dosage* / Q000031:analogs & derivatives / Q000097:blood; D055815:Young Adult
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D