title: [Photochemical reaction types of the azole fungicide fluconazole under UV-vis irradiation].
abstract: This study selected the azole fungicide fluconazole as a model compound, and investigated its photodegradation kinetics and photoreaction types in pure water. It was found that under UV-vis irradiation (lambda > 200 nm), the fluconazole photodegraded fast and followed the pseudo-first-order kinetics, whereas under simulated sunlight (lambda > 290 nm), photodegradation did not occur. The ROS scavenging experiments and competition kinetic examination indicated that the compound underwent both direct photolysis and self-sensitized photooxidation via *OH other than 1O2. The bimolecular rate constant for the reaction between fluconazole and *OH was (5.95 +/- 0.58) x 10(9) L x (mol x s)(-1), and the corresponding environmental half-life was calculated to be (32.41 +/- 3.16) h in surface waters. Furthermore, it was deduced from the photodegradation product identification that the UV-vis degradation pathways involved photoinduced defluorination, hydrolysis and photooxidation.
authors.affiliation: Key Laboratory for Ecological Environment in Coastal Areas (SOA), National Marine Environmental Monitoring Center, Dalian 116023, China. lkge@nmemc.gov.cn
authors.forename: Lin-Ke
authors.initials: LK
authors.lastname: Ge
authors.forename: Kai
authors.initials: K
authors.lastname: Li
authors.forename: Kai
authors.initials: K
authors.lastname: Yang
authors.forename: Guang-Shui
authors.initials: GS
authors.lastname: Na
authors.forename: Chun-Yan
authors.initials: CY
authors.lastname: Yu
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
authors.forename: Zi-Wei
authors.initials: ZW
authors.lastname: Yao
mesh_terms: D015725:Fluconazole / Q000737:chemistry*; D005659:Fungicides, Industrial / Q000737:chemistry*; D006207:Half-Life; D007700:Kinetics; D010084:Oxidation-Reduction; D010782:Photolysis; D013472:Sunlight; D014466:Ultraviolet Rays; D014867:Water / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000737:chemistry
chemical_list: D005659:Fungicides, Industrial; D014874:Water Pollutants, Chemical; D014867:Water; D015725:Fluconazole