title: Time-Motion Analysis of Four Automated Systems for the Detection of Chlamydia trachomatis and Neisseria gonorrhoeae by Nucleic Acid Amplification Testing.
abstract: Next-generation diagnostics for Chlamydia trachomatis and Neisseria gonorrhoeae are available on semi- or fully-automated platforms. These systems require less hands-on time than older platforms and are user friendly. Four automated systems, the ABBOTT m2000 system, Becton Dickinson Viper System with XTR Technology, Gen-Probe Tigris DTS system, and Roche cobas 4800 system, were evaluated for total run time, hands-on time, and walk-away time. All of the systems evaluated in this time-motion study were able to complete a diagnostic test run within an 8-h work shift, instrument setup and operation were straightforward and uncomplicated, and walk-away time ranged from approximately 90 to 270 min in a head-to-head comparison of each system. All of the automated systems provide technical staff with increased time to perform other tasks during the run, offer easy expansion of the diagnostic test menu, and have the ability to increase specimen throughput.
authors.affiliation: Indiana University School of Medicine, Indianapolis, IN, USA jaawilli@iupui.edu.
authors.forename: James A
authors.initials: JA
authors.lastname: Williams
authors.affiliation: Indiana University School of Medicine, Indianapolis, IN, USA.
authors.forename: Laura
authors.initials: L
authors.lastname: Eddleman
authors.affiliation: Indiana University School of Medicine, Indianapolis, IN, USA.
authors.forename: Amy
authors.initials: A
authors.lastname: Pantone
authors.affiliation: TriCore Reference Laboratories, Albuquerque, NM, USA.
authors.forename: Regina
authors.initials: R
authors.lastname: Martinez
authors.affiliation: TriCore Reference Laboratories, Albuquerque, NM, USA Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
authors.forename: Stephen
authors.initials: S
authors.lastname: Young
authors.affiliation: Indiana University School of Medicine, Indianapolis, IN, USA Indiana University School of Public Health, Bloomington, IN, USA.
authors.forename: Barbara
authors.initials: B
authors.lastname: Van Der Pol
mesh_terms: D057205:Automation, Laboratory / Q000379:methods / Q000706:statistics & numerical data*; D002690:Chlamydia Infections / Q000175:diagnosis / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000235:genetics*; D006069:Gonorrhea / Q000175:diagnosis / Q000382:microbiology; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods / Q000706:statistics & numerical data*; D009344:Neisseria gonorrhoeae / Q000235:genetics*; D021141:Nucleic Acid Amplification Techniques / Q000379:methods / Q000706:statistics & numerical data*; D011933:Reagent Kits, Diagnostic; D013996:Time and Motion Studies
chemical_list: D011933:Reagent Kits, Diagnostic
keywords: Chlamydia trachomatis; Neisseria gonorrhoeae; Time motion; automation; nucleic acid diagnostics