title: [First experiences of laparoscopic radical cystectomy].
abstract: OBJECTIVE
  We determined whether laparoscopic radical cystectomy (LRC) was useful for the patients with bladder cancer.
  
  
  METHODS
  We investigated the surgical outcome of LRC in the initial 30 patients with bladder cancer.
  
  
  RESULTS
  Mean patients age was 68 (54-81) years old. Twenty six male and 4 female were enrolled. Lymphnode dissection was variably performed under aeroperitoneum. Twenty six patients were undergone ileal conduit and 4 patients were undergone ileal neobladder as urinary diversion. The urinary diversion of all cases was undergone extra-corporeally. Seventeen patients were received platinum based neo and adjivant-chemotherapy. Mean surgical time was 684 (398-950) min, and mean aeroperitoneum time was 418 (235-660) min. Intraoperative major complications were ureter injury and blood loss. Mean blood loss was 1,063 (150-2,730) ml intraoperatively. Ileus and acute pyeronephritis were observed in the 3 patients postoperatively. Seven patients relapsed and 2 patients died with bladder cancer in 14.9 months of median follow-up period (0.7-35.9) after the surgery. Progression free survival rate and overall survival rate at a year after surgery were 75.2% and 100%, respectively.
  
  
  CONCLUSIONS
  The surgical therapy with LRC was well tolerated and successful in the patients with bladder cancer.
authors.affiliation: Department of Urology, School of Medicine, Kochi University, Nankoku, Japan. karasima@kochi-u.ac.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Karashima
authors.forename: Keiji
authors.initials: K
authors.lastname: Inoue
authors.forename: Satoshi
authors.initials: S
authors.lastname: Fukata
authors.forename: Shingo
authors.initials: S
authors.lastname: Ashida
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Shimamoto
authors.forename: Hideo
authors.initials: H
authors.lastname: Fukuhara
authors.forename: Takashi
authors.initials: T
authors.lastname: Anchi
authors.forename: Maiko
authors.initials: M
authors.lastname: Kamei
authors.forename: Kenji
authors.initials: K
authors.lastname: Tamura
authors.forename: Ichiro
authors.initials: I
authors.lastname: Yamasaki
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kamada
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Satake
authors.forename: Taro
authors.initials: T
authors.lastname: Shuin
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D015653:Cystectomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D015996:Survival Rate; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D014547:Urinary Diversion / Q000379:methods
chemical_list: D002945:Cisplatin