title: [A case of laryngeal necrosis following concurrent chemoradiotherapy for advanced hypopharyngeal cancer after insertion of a nasogastric tube].
abstract: A 62-year-old male with cT4bN2cM0 hypopharyngeal carcinoma with ipsilateral vocal cord fixation was initially treated with concurrent chemoradiotherapy. Since the patient complained of dysphagia caused by mucositis, a nasogastric tube was placed on the day of irradiation with a dose of 20 Gy. Bilateral vocal cord fixation and laryngeal necrosis became evident 3 weeks after the concurrent chemoradiotherapy. He underwent a total pharyngolaryngectomy (neck dissection, and reconstruction with a free jejunal graft) followed by adjuvant chemotherapy. It is highly suspected that the nasogastric tube compressed the mucosa of the post cricoid region, resulting in laryngeal necrosis.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kitamura
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Tomiyama
authors.forename: Tadashi
authors.initials: T
authors.lastname: Yoshii
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Takenaka
authors.forename: Hidenori
authors.initials: H
authors.lastname: Inohara
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery*; D059248:Chemoradiotherapy / Q000009:adverse effects* / Q000379:methods; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000473:pathology* / Q000628:therapy*; D007825:Laryngectomy / Q000379:methods; D007830:Larynx / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009336:Necrosis / Q000209:etiology; D010611:Pharyngectomy / Q000379:methods; D000077195:Squamous Cell Carcinoma of Head and Neck; D016896:Treatment Outcome