title: Laparoscopic emergency surgery for diverticular disease that failed medical treatment: a valuable option? Results of a retrospective comparative cohort study.
abstract: BACKGROUND
  Laparoscopic surgery has become the standard of treatment for elective management of diverticular disease. However, its use in the acute setting remains controversial.
  
  
  OBJECTIVE
  The aim of this study is to compare the outcomes of laparoscopic surgery with open surgery in the acute management of complicated diverticular disease that failed initial medical treatment.
  
  
  METHODS
  This is a single-center comparative retrospective cohort study.
  
  
  METHODS
  Patients undergoing surgery for complicated diverticular disease after an attempt at medical treatment from 2000 to 2011 were selected.
  
  
  METHODS
  Laparoscopic versus open surgery was compared.
  
  
  METHODS
  The primary outcomes were overall 30-day morbidity and mortality. Secondary outcomes were length of stay, time to resume diet, and need for a permanent stoma.
  
  
  RESULTS
  Forty-two patients were identified by using medical records: 24 laparoscopic surgery and 18 open surgery. Baseline demographics, ASA classification, Acute Physiology and Chronic Health Evaluation scores, Hinchey classification, and Charlson Comorbidity Index did not differ between groups. The mean operative time was 36 minutes longer (p = 0.05) and blood loss was 460 mL less (p < 0.001) for laparoscopic surgery. Two patients (8.3%) in the laparoscopic surgery group required conversion to open surgery. There was no mortality. Overall morbidity was lower favoring laparoscopic surgery (16.7% vs 55.6%; p = 0.01). Two patients in the laparoscopic surgery group experienced an anastomotic leak compared with none in the open surgery group. Mean time to resume diet (3 vs 6.5 days; p < 0.01) and length of stay (5 vs 8 days; p = 0.04) were shorter for the laparoscopic surgery group. Rate of permanent stoma at last follow-up (median, 332 days) did not differ significantly between groups.
  
  
  CONCLUSIONS
  This study is limited by selection bias.
  
  
  CONCLUSIONS
  Compared with open surgery, laparoscopic surgery for patients in whom medical treatment for complicated diverticular disease failed is associated with favorable outcomes, including a reduced rate of morbidity and a shorter length of stay. When applied to selected patients, this approach appears to be a safe procedure with a low rate of conversion.
authors.affiliation: 1Department of Surgery, Faculty of Medicine, Université Laval, Québec City, Québec, Canada 2Department of Social and Preventive Medicine, Faculty of Medicine, Université Laval, Québec City, Québec, Canada 3Department of Surgery, CHU de Québec - Hôpital Saint-François d'Assise, Québec Centre for Minimally Invasive Surgery (QCMIS), Québec City, Québec, Canada.
authors.forename: François
authors.initials: F
authors.lastname: Letarte
authors.forename: Julie
authors.initials: J
authors.lastname: Hallet
authors.forename: Sébastien
authors.initials: S
authors.lastname: Drolet
authors.forename: Roger
authors.initials: R
authors.lastname: Charles Grégoire
authors.forename: Alexandre
authors.initials: A
authors.lastname: Bouchard
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Gagné
authors.forename: Claude
authors.initials: C
authors.lastname: Thibault
authors.forename: Philippe
authors.initials: P
authors.lastname: Bouchard
mesh_terms: D000368:Aged; D015331:Cohort Studies; D003082:Colectomy / Q000379:methods*; D061887:Conversion to Open Surgery; D004238:Diverticulitis / Q000188:drug therapy / Q000601:surgery*; D004638:Emergency Treatment; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000188:drug therapy / Q000601:surgery*; D010535:Laparoscopy / Q000379:methods*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D017211:Treatment Failure; D016896:Treatment Outcome