title: The autism puzzle: challenging a mechanistic model on conceptual and historical grounds.
abstract: Although clinicians and researchers working in the field of autism are generally not concerned with philosophical categories of kinds, a model for understanding the nature of autism is important for guiding research and clinical practice. Contemporary research in the field of autism is guided by the depiction of autism as a scientific object that can be identified with systematic neuroscientific investigation. This image of autism is compatible with a permissive account of natural kinds: the mechanistic property cluster (MPC) account of natural kinds, recently proposed as the model for understanding psychiatric disorders. Despite the heterogeneity, multicausality and fuzzy boundaries that complicate autism research, a permissive account of natural kinds (MPC kinds) provides prescriptive guidance for the investigation of objective causal mechanisms that should inform nosologists in their attempt to carve autism's boundaries at its natural joints. However, this essay will argue that a mechanistic model of autism is limited since it disregards the way in which autism relates to ideas about what kind of behavior is abnormal. As historical studies and definitions of autism show, normative issues concerning disability, impairment and societal needs have been and still are inextricably linked to how we recognize and understand autism. The current search for autism's unity in neurobiological mechanisms ignores the values, social norms and various perspectives on mental pathology that play a significant role in 'the thing called autism'. Autism research needs to engage with these issues in order to achieve more success in the effort to become clinically valuable.
authors.affiliation: Theory and History of Psychology, University of Groningen, Grote Kruisstraat 2/1, 9712 TS Groningen, The Netherlands. berendverhoeff@gmail.com.
authors.forename: Berend
authors.initials: B
authors.lastname: Verhoeff
mesh_terms: D001321:Autistic Disorder / Q000175:diagnosis / Q000266:history; D003210:Concept Formation; D003469:Culture; D003937:Diagnosis, Differential; D039721:Diagnostic and Statistical Manual of Mental Disorders; D049673:History, 20th Century; D006801:Humans; D008962:Models, Theoretical; D010686:Philosophy, Medical; D012106:Research