title: Proregenerative properties of ECM molecules.
abstract: After traumatic injuries to the nervous system, regrowing axons encounter a complex microenvironment where mechanisms that promote regeneration compete with inhibitory processes. Sprouting and axonal regrowth are key components of functional recovery but are often counteracted by inhibitory molecules. This review covers extracellular matrix molecules that support neuron axonal outgrowth.
authors.affiliation: Department of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden.
authors.forename: Stefan
authors.initials: S
authors.lastname: Plantman
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D004195:Disease Models, Animal; D016326:Extracellular Matrix Proteins / Q000502:physiology*; D005353:Fibronectins / Q000502:physiology; D006801:Humans; D016023:Integrins / Q000502:physiology; D007797:Laminin / Q000502:physiology; D009416:Nerve Regeneration / Q000502:physiology*; D009419:Nerve Tissue Proteins / Q000502:physiology; D009474:Neurons / Q000502:physiology; D053495:Osteopontin / Q000502:physiology; D059348:Peripheral Nerve Injuries / Q000503:physiopathology; D013119:Spinal Cord Injuries / Q000503:physiopathology; D019699:Thrombospondins / Q000502:physiology; D019096:Vitronectin / Q000502:physiology
chemical_list: D016326:Extracellular Matrix Proteins; D005353:Fibronectins; D016023:Integrins; D007797:Laminin; D009419:Nerve Tissue Proteins; D019699:Thrombospondins; D019096:Vitronectin; D053495:Osteopontin