title: Synthesis and antibacterial activity of monocyclic 3-carboxamide tetramic acids.
abstract: A chemical library of carboxamide-substituted tetramates designed by analogy with antibacterial natural products, a method for their rapid construction, and the evaluation of their antibacterial activity is reported.
authors.affiliation: Chemistry Research Laboratory, University of Oxford, Mansfield Rd, University of Oxford, OX1 3TA, UK.
authors.forename: Yong-Chul
authors.initials: YC
authors.lastname: Jeong
authors.forename: Mark G
authors.initials: MG
authors.lastname: Moloney
keywords: acylation; antibacterial; drug discovery; natural products; tetramate