title: Electrical and mechanical office-based neuromodulation.
abstract: Overactive bladder (OAB) is commonly encountered in urologic practice. Treatment algorithms begin with conservative therapy and pharmacotherapy with antimuscarinics. Some patients do not receive adequate relief from these methods or they do not tolerate side effects from pharmacotherapy. A test stimulation for sacral neuromodulation and percutaneous tibial nerve stimulation are office-based techniques that are commonly used as the next step in the algorithm of care in patients with OAB. These techniques are efficacious and approved by the Food and Drug Administration for treatment of overactive bladder and its associated symptoms.
authors.affiliation: Division of Urology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.
authors.forename: Ravi
authors.initials: R
authors.lastname: Kacker
authors.forename: Aaron
authors.initials: A
authors.lastname: Lay
authors.forename: Anurag
authors.initials: A
authors.lastname: Das
mesh_terms: D004599:Electric Stimulation Therapy; D006801:Humans; D008160:Lumbosacral Plexus; D018727:Muscarinic Antagonists / Q000627:therapeutic use; D013979:Tibial Nerve; D053201:Urinary Bladder, Overactive / Q000628:therapy*
chemical_list: D018727:Muscarinic Antagonists
keywords: Electric stimulation therapy; Neuromodulation; Overactive bladder; Sacral nerve; Tibial nerve