title: Colloidal and biological properties of cationic single-chain and dimeric surfactants.
abstract: The colloidal and biological properties of the two single-chain surfactants N-benzyl-N,N-dimethyl-N-(1-dodecyl)ammonium bromide (PH12) and N-cyclohexylmethyl-N,N-dimethyl-N-(1-dodecyl)ammonium bromide (CH12) and their two dimeric counterparts N,N'-(1,3-phenylenebis(methylene))bis(N,N-dimethyl-N-(1-dodecyl)ammonium dibromide (12PH12) and N,N'-(cyclohexane-1,3-diylbis(methylene))bis(N,N-dimethyl-N-(1-dodecyl)ammonium dibromide (12CH12) were investigated. The thermodynamic functions of the self-aggregation process were estimated by using calorimetric measurements and the micellization enthalpy values, ΔHM, were examined considering the different enthalpic contributions to ΔHM. In the investigation of the structure-property relationship, it was found that the surfactant structure does not influence practically the foamability of the surfactants, but it plays a key role in their solubilization capacity, antimicrobial activity and biodegradability.
authors.affiliation: Departamento de Microbiología y Parasitología, Universidad de Sevilla, C/Profesor García González 2, 41012 Sevilla, Spain; Instituto de Recursos Naturales y Agrobiología de Sevilla, CSIC, Avda. Reina Mercedes 10, 41012 Sevilla, Spain; Departamento de Química Física, Universidad de Sevilla, C/Profesor García González 1, 41012 Sevilla, Spain.
authors.forename: Victoria Isabel
authors.initials: VI
authors.lastname: Martín
authors.affiliation: Departamento de Microbiología y Parasitología, Universidad de Sevilla, C/Profesor García González 2, 41012 Sevilla, Spain.
authors.forename: Rafael R
authors.initials: RR
authors.lastname: de la Haba
authors.affiliation: Departamento de Microbiología y Parasitología, Universidad de Sevilla, C/Profesor García González 2, 41012 Sevilla, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Ventosa
authors.affiliation: Instituto de Recursos Naturales y Agrobiología de Sevilla, CSIC, Avda. Reina Mercedes 10, 41012 Sevilla, Spain.
authors.forename: Eleonora
authors.initials: E
authors.lastname: Congiu
authors.affiliation: Instituto de Recursos Naturales y Agrobiología de Sevilla, CSIC, Avda. Reina Mercedes 10, 41012 Sevilla, Spain.
authors.forename: José Julio
authors.initials: JJ
authors.lastname: Ortega-Calvo
authors.affiliation: Departamento de Química Física, Universidad de Sevilla, C/Profesor García González 1, 41012 Sevilla, Spain. Electronic address: moya@us.es.
authors.forename: María Luisa
authors.initials: ML
authors.lastname: Moyá
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001673:Biodegradation, Environmental / Q000187:drug effects; D002151:Calorimetry; D002412:Cations / Q000737:chemistry*; D003102:Colloids / Q000737:chemistry*; D019281:Dimerization; D008823:Micelles; D008826:Microbial Sensitivity Tests; D012995:Solubility; D012996:Solutions; D013499:Surface Properties; D013501:Surface-Active Agents / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D000890:Anti-Infective Agents; D002412:Cations; D003102:Colloids; D008823:Micelles; D012996:Solutions; D013501:Surface-Active Agents
keywords: Antimicrobial activity; Biodegradability; Cationic surfactants; Dimeric surfactants; Foamability; Isothermal titration calorimetry; Single-chain surfactants; Solubilization capacity