title: Redistribution of histones during unfolding of chromosomal DNA.
abstract: Just in the course of unfolding of chromosomal deoxyribonucleoproteins performed in the absence of magnesium ions all DNA-bound histones may be redistributed. This type of redistribution is completely blocked in already 'unfolded' DNP preparations. If the unfolding-induced histone redistribution is allowed it leads to a significant decrease of the average length of free DNA segments in the unfolded, histone F1-depleted DNP. The implications of these data on the mode of DNA packing in chromatin are discussed.
authors.affiliation: Institute of Molecular Biology, Academy of Sciences of the U.S.S.R., Moscow, USSR.
authors.forename: A J
authors.initials: AJ
authors.lastname: Varshavsky
authors.forename: G P
authors.initials: GP
authors.lastname: Georgiev