title: Granulomatous pododermatitis in the digits caused by Fusarium proliferatum in a cat.
abstract: To the best of our knowledge, we present here the first report of a case involving granulomatous pododermatitis caused by Fusarium proliferatum in a 10-year-old female cat. A cutaneous mass developed on the foot-pad of the right hind leg. Nodular granulomatous dermatitis with numerous macrophages and multinucleated giant cells containing cytoplasmic fungal structures were revealed on histological examination. Periodic acid-Schiff reaction and Fungi-Fluor staining clearly revealed irregular, septate fungal hyphae englobed by macrophages and multinucleated giant cells. Polymerase chain reaction and sequence analysis targeting three domains of the extracted fungal DNA revealed 100% amplicon homology with F. proliferatum.
authors.affiliation: Research Institute of Biosciences, Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan.
authors.forename: Go
authors.initials: G
authors.lastname: Sugahara
authors.forename: Akio
authors.initials: A
authors.lastname: Kiuchi
authors.forename: Reiko
authors.initials: R
authors.lastname: Usui
authors.forename: Ryouichi
authors.initials: R
authors.lastname: Usui
authors.forename: Takayuki
authors.initials: T
authors.lastname: Mineshige
authors.forename: Junichi
authors.initials: J
authors.lastname: Kamiie
authors.forename: Kinji
authors.initials: K
authors.lastname: Shirota
mesh_terms: D000818:Animals; D001483:Base Sequence; D002371:Cat Diseases / Q000276:immunology / Q000382:microbiology* / Q000473:pathology*; D002415:Cats; D016000:Cluster Analysis; D017931:DNA Primers / Q000235:genetics; D003872:Dermatitis / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D005260:Female; D060585:Fusariosis / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D005670:Fusarium / Q000235:genetics / Q000276:immunology*; D006614:Hindlimb / Q000473:pathology; D006652:Histological Techniques / Q000662:veterinary; D008969:Molecular Sequence Data; D010802:Phylogeny; D017422:Sequence Analysis, DNA / Q000662:veterinary
chemical_list: D017931:DNA Primers