title: Risk factors for multidrug-resistant bacteremia in hospitalized cancer patients with febrile neutropenia: a cohort study.
abstract: We conducted a prospective cohort study in a single tertiary hospital with the aim of assessing predictors of multidrug-resistant bacteremia in 307 cases of febrile neutropenia in adult patients with cancer. On multivariate analysis using stepwise logistic regression, age (P = .009), duration of neutropenia (P = .022), and presence of an indwelling central venous catheter (P = .022) were associated with bloodstream infection by multidrug-resistant bacteria.
authors.affiliation: Infectious Diseases Division and Infection Control Committee, Hospital de Clínicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
authors.forename: Regis G
authors.initials: RG
authors.lastname: Rosa
authors.affiliation: Infectious Diseases Division and Infection Control Committee, Hospital de Clínicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
authors.forename: Luciano Z
authors.initials: LZ
authors.lastname: Goldani
authors.affiliation: Infectious Diseases Division and Infection Control Committee, Hospital de Clínicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. Electronic address: rpsantos@hcpa.ufrgs.br.
authors.forename: Rodrigo P
authors.initials: RP
authors.lastname: dos Santos
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000453:epidemiology*; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification*; D015331:Cohort Studies; D024901:Drug Resistance, Multiple, Bacterial; D064147:Febrile Neutropenia / Q000150:complications* / Q000453:epidemiology*; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications* / Q000628:therapy; D011446:Prospective Studies; D012307:Risk Factors; D062606:Tertiary Care Centers; D055815:Young Adult
keywords: Bacterial; Drug resistance; Fever; Immunocompromised host