title: Simultaneous LC-MS/MS analysis of glyphosate, glufosinate, and their metabolic products in beer, barley tea, and their ingredients.
abstract: Glyphosate and glufosinate are non-selective herbicides that have been extensively used worldwide. Their ionic and water-soluble characteristics often make it difficult to analyze them, especially in food components. A method was developed in this study for the simultaneous analysis of glyphosate, glufosinate, and three metabolic products in beer, barley tea, and their ingredients (malt and corn). The analytical samples were extracted with H2O, purified with a strong anion-exchange solid-phase extraction (SPE) cartridge, and then analyzed by liquid chromatography tandem mass spectrometry (LC-MS/MS) with an anion-exchange high-performance liquid chromatography (HPLC) column. This method enabled a rapid and sensitive analysis [limit of quantification (LOQ) = 10 µg/kg] of the herbicides to be achieved.
authors.affiliation: Research Laboratories for Food Safety Chemistry, Asahi Group Holdings Ltd.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Nagatomi
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Yoshioka
authors.forename: Mayumi
authors.initials: M
authors.lastname: Yanagisawa
authors.forename: Atsuo
authors.initials: A
authors.lastname: Uyama
authors.forename: Naoki
authors.initials: N
authors.lastname: Mochizuki
mesh_terms: D000613:Aminobutyrates / Q000302:isolation & purification*; D001515:Beer / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid / Q000379:methods; D004785:Environmental Pollutants / Q000302:isolation & purification*; D006540:Herbicides / Q000302:isolation & purification*; D001467:Hordeum / Q000737:chemistry*; D006801:Humans; D007474:Ion Exchange; D010936:Plant Extracts / Q000737:chemistry*; D052616:Solid Phase Extraction; D053719:Tandem Mass Spectrometry / Q000379:methods; D014867:Water
chemical_list: D000613:Aminobutyrates; D004785:Environmental Pollutants; D006540:Herbicides; D010936:Plant Extracts; D014867:Water; C003121:phosphinothricin