title: Oral clonidine in the management of acquired opioid dependency.
abstract: Clonidine is a nonnarcotic analgesic historically used as a nasal decongestant and more recently established as an antihypertensive agent in adults. Because of its sedative properties with few adverse effects, clonidine has also been reported to be an effective pharmacologic agent for the treatment of neonatal abstinence syndrome (NAS). The use of oral clonidine as a primary or secondary agent in the treatment of NAS has been found to reduce hospitalization and duration of treatment in this population.
authors.forename: Michele J
authors.initials: MJ
authors.lastname: Beaulieu
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage / Q000627:therapeutic use*; D000701:Analgesics, Opioid / Q000009:adverse effects*; D002648:Child; D003000:Clonidine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009357:Neonatal Abstinence Syndrome / Q000188:drug therapy*; D009293:Opioid-Related Disorders / Q000188:drug therapy*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000188:drug therapy*
chemical_list: D000700:Analgesics; D000701:Analgesics, Opioid; D003000:Clonidine
keywords: NAS; clonidine; pharmacology