title: When cells become organelle donors.
abstract: More than 40 variations of intercellular organelle transfer, such as a mitochondria or lysosome originating in one cell being transported to another cell, have been described. We review the mechanisms and subcellular structures by which, and conditions under which, transfer occurs, with particular attention paid to the role of external cell stress in activating transfer. We propose a research agenda for answering key questions in this burgeoning field.
authors.affiliation: Lung Biology Laboratory, Department of Medicine, and Department of Physiology & Cellular Biophysics, Columbia University, College of Physicians & Surgeons, New York.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Rogers
authors.forename: Jahar
authors.initials: J
authors.lastname: Bhattacharya
mesh_terms: D000818:Animals; D001692:Biological Transport; D002450:Cell Communication; D006801:Humans; D015388:Organelles / Q000502:physiology*; D015398:Signal Transduction; D013312:Stress, Physiological