title: Mechanism and physiological significance of growth factor-related autophagy.
abstract: Growth factors, typically defined as natural substances capable of stimulating cell growth and differentiation, are vital regulators for the survival of metazoan cells. In this review, we will focus on growth factor signaling pathways that are closely related to autophagy induction and discuss the critical roles of this fascinating cellular process in intracellular energy homeostasis, cell fate determination, and pathophysiological regulation.
authors.affiliation: State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.
authors.forename: Terytty Yang
authors.initials: TY
authors.lastname: Li
authors.forename: Shu-Yong
authors.initials: SY
authors.lastname: Lin
authors.forename: Sheng-Cai
authors.initials: SC
authors.lastname: Lin
mesh_terms: D000818:Animals; D017209:Apoptosis; D001343:Autophagy; D006706:Homeostasis; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D036341:Intercellular Signaling Peptides and Proteins; D051057:Proto-Oncogene Proteins c-akt