title: Same day tri-modality functional brain mapping prior to resection of a lesion involving eloquent cortex: technical feasibility.
abstract: Non-invasive functional evaluation of the brain complements structural MRI imaging and has largely supplanted invasive techniques such as awake craniotomy. Techniques used for functional mapping of the brain include BOLD-functional MRI (fMRI), magnetoencephalography (MEG), and transcranial magnetic stimulation (TMS). We describe the case of a right-handed patient with a lesion centered in the left inferior perirolandic cortex who underwent fMRI, MEG, and TMS on a single day to facilitate maximal lesion resection while preserving eloquent cortex and eloquent white matter tracts.
authors.affiliation: Department of Radiology, Department of Pediatrics, Division of Clinical Neurosciences, Department of Neurosurgery, Department of Ophthalmology, Division of Neurology University of Tennessee, Health Science Center; Memphis, TN, USA - Le Bonheur Neuroscience Institute, Le Bonheur Children's Hospital; Memphis, TN, USA - achoudhri@uthsc.edu.
authors.forename: Asim F
authors.initials: AF
authors.lastname: Choudhri
authors.forename: Shalini
authors.initials: S
authors.lastname: Narayana
authors.forename: Roozbeh
authors.initials: R
authors.lastname: Rezaie
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Whitehead
authors.forename: Samuel S
authors.initials: SS
authors.lastname: McAfee
authors.forename: James W
authors.initials: JW
authors.lastname: Wheless
authors.forename: Frederick A
authors.initials: FA
authors.lastname: Boop
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Papanicolaou
mesh_terms: D001921:Brain / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D001931:Brain Mapping / Q000379:methods*; D001932:Brain Neoplasms / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D059907:Functional Neuroimaging / Q000379:methods*; D005910:Glioma / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D015225:Magnetoencephalography; D008875:Middle Aged; D038361:Neuronavigation / Q000379:methods; D050781:Transcranial Magnetic Stimulation
keywords: brain tumor; functional MRI; image-guided navigation; magnetoencephalography; multimodality; transcranial magnetic stimulation