title: [How I treat dandruff].
abstract: Dandruff and seborrheic dermatitis form a continuum of desquamative conditions associated with the excessive colonization of the stratum corneum by yeasts of the genus Malassezia spp. Such colonization is heterogeneous in density, ranging from discrete to abundant according to the fungal ability to adhere to individual corneocytes. The rate of action of antidandruff shampoos shed some doubts about a direct antifungal effect, but rather suggests the involvement of innate immune defenses and the chemical alteration of molecular adhesion modalities between Malassezia and corneocytes.
authors.affiliation: Unilab Lg, Service de Dermatopathologie, CHU de Liege. claudine.franchimont@ulg.ac.be
authors.forename: C
authors.initials: C
authors.lastname: Piérard-Franchimont
authors.forename: G E
authors.initials: GE
authors.lastname: Piérard
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D063807:Dandruff / Q000188:drug therapy* / Q000382:microbiology* / Q000473:pathology; D012628:Dermatitis, Seborrheic / Q000188:drug therapy* / Q000382:microbiology* / Q000473:pathology; D006203:Hair Preparations / Q000627:therapeutic use; D006801:Humans; D008290:Malassezia
chemical_list: D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D006203:Hair Preparations