title: Outbreak of herpangina in the Brazilian Amazon in 2009 caused by Enterovirus B.
abstract: In October 2009, our laboratory was contacted by a Brazilian Public Health organization regarding a severe community outbreak of an acute exanthematic and febrile disease in the Brazilian Amazon that primarily affected children. A total of 44 patients with febrile disease were identified by the local public health system, 37 of whom were children between 1 and 9 years of age. Molecular virological and phylogenetic characterization revealed that enterovirus B was the etiological agent of this outbreak, which was characterized by a clinical presentation known as herpangina.
authors.affiliation: Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Antônio Carlos 6627, Caixa Postal 486, Belo Horizonte, MG, 31270-901, Brazil.
authors.forename: D B
authors.initials: DB
authors.lastname: Oliveira
authors.forename: R K
authors.initials: RK
authors.lastname: Campos
authors.forename: M S
authors.initials: MS
authors.lastname: Soares
authors.forename: R B
authors.initials: RB
authors.lastname: Barros
authors.forename: T C A
authors.initials: TC
authors.lastname: Batista
authors.forename: P C P
authors.initials: PC
authors.lastname: Ferreira
authors.forename: C A
authors.initials: CA
authors.lastname: Bonjardim
authors.forename: G S
authors.initials: GS
authors.lastname: Trindade
authors.forename: J S
authors.initials: JS
authors.lastname: Abrahão
authors.forename: Erna Geessien
authors.initials: EG
authors.lastname: Kroon
mesh_terms: D000328:Adult; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D029822:Enterovirus B, Human / Q000235:genetics / Q000302:isolation & purification*; D004769:Enterovirus Infections / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D006557:Herpangina / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D006801:Humans; D007223:Infant; D010802:Phylogeny