title: High-fidelity stereochemical memory in a Fe(II)4L4 tetrahedral capsule.
abstract: A new class of Fe(II)4L4 capsules, based upon a tritopic trialdehyde subcomponent, is reported. One such capsule was prepared diastereoselectively through the incorporation of a chiral amine residue. This amine was displaced by an achiral one, while maintaining the stereochemistry of the cage framework (99% ee); this cage retained its stereochemistry even after 4 days at 90 °C. Mechanistic studies indicate the memory displayed by this capsule to be the result of effective stereochemical communication between the metal centers mediated by the rigid 3-fold-symmetric faces, in combination with a stepwise substitution mechanism.
authors.affiliation: Department of Chemistry, University of Cambridge , Lensfield Road, Cambridge CB2 1EW, United Kingdom.
authors.forename: Ana M
authors.initials: AM
authors.lastname: Castilla
authors.forename: Naoki
authors.initials: N
authors.lastname: Ousaka
authors.forename: Rana A
authors.initials: RA
authors.lastname: Bilbeisi
authors.forename: Elisa
authors.initials: E
authors.lastname: Valeri
authors.forename: Tanya K
authors.initials: TK
authors.lastname: Ronson
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Nitschke