title: Novel antiplatelet and anticoagulant agents in the cardiac care unit.
abstract: This article reviews the pivotal studies of several novel antiplatelet (prasugrel and ticagrelor) and anticoagulant (dabigatran, rivaroxaban, and apixaban) agents. The clinical use of these drugs in cardiac intensive care is discussed, focusing on the management of acute coronary syndromes, ischemic stroke, atrial fibrillation, and venous thromboembolism.
authors.affiliation: Department of Medicine, The Cardiovascular Institute, Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai, Fifth Avenue at 100th Street, New York, NY 10029-6574, USA.
authors.forename: Vaani Panse
authors.initials: VP
authors.lastname: Garg
authors.forename: Jonathan L
authors.initials: JL
authors.lastname: Halperin
mesh_terms: D054058:Acute Coronary Syndrome / Q000188:drug therapy*; D000208:Acute Disease; D000284:Administration, Oral; D000925:Anticoagulants / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000517:prevention & control; D003325:Coronary Care Units; D003422:Critical Care; D004359:Drug Therapy, Combination; D004554:Electric Countershock / Q000379:methods; D006350:Heart Valve Prosthesis; D006470:Hemorrhage / Q000139:chemically induced / Q000517:prevention & control; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D011655:Pulmonary Embolism / Q000517:prevention & control; D013997:Time Factors; D054556:Venous Thromboembolism / Q000517:prevention & control; D020246:Venous Thrombosis / Q000517:prevention & control
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors
keywords: Acute coronary syndrome; Anticoagulants; Antiplatelet drugs; Atrial fibrillation; Percutaneous coronary intervention; Stroke; Venous thromboembolism