title: Improvement of gastroesophageal reflux symptoms after standardized laparoscopic sleeve gastrectomy.
abstract: BACKGROUND
  Gastroesophageal reflux disease (GERD) is present in half of morbidly obese patients. Published data reporting the results of laparoscopic sleeve gastrectomy (LSG) in patients with GERD are contradictory. We have shown in a previous study that symptoms of GERD can be reduced for up to 12 months after LSG with careful attention to surgical technique. The present study prospectively evaluated the effect of a standardized LSG technique on the incidence of postoperative GERD symptoms in a larger sample, and followed patients for up to 22 months.
  
  
  METHODS
  This was a concurrent cohort study. All patients who underwent LSG at our center completed a standard multidisciplinary preoperative evaluation and were followed prospectively.
  
  
  RESULTS
  A total of 382 patients underwent surgery. There were no cases of death or fistula. GERD was diagnosed in 170 patients (44.5 %) preoperatively, and hiatal hernia (HH) was detected in 142 patients (37.2 %) intraoperatively. Between 6 and 22 months postoperatively, 373 patients were completely evaluated. Ten (2.6 %) had GERD symptoms 6-22 months postoperatively, and 94 % of patients with preoperative GERD symptoms were asymptomatic at follow-up 6-22 months after LSG. Only 1 patient (0.5 %) of a subgroup of 174 without HH or esophagitis at preoperative evaluation had GERD at follow-up.
  
  
  CONCLUSIONS
  Our results confirm that, contrary to previous reports of LSG in the literature, careful attention to surgical technique can result in significantly reduced GERD symptoms up to 22 months postoperatively suggesting that LSG does not predispose patients to GERD during that period.
authors.affiliation: Minimally Invasive Surgery Department, Clinica Bautista, Carrera 38 calle 71 esquina, Barranquilla, Colombia, jorgedaez@gmail.com.
authors.forename: Jorge
authors.initials: J
authors.lastname: Daes
authors.forename: Manuel E
authors.initials: ME
authors.lastname: Jimenez
authors.forename: Nadim
authors.initials: N
authors.lastname: Said
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Dennis
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects / Q000379:methods; D005764:Gastroesophageal Reflux / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000601:surgery; D011183:Postoperative Complications / Q000453:epidemiology; D017792:Surgical Stapling; D055815:Young Adult