title: Antibacterial screening of traditional herbal plants and standard antibiotics against some human bacterial pathogens.
abstract: Chloroformic and isoamyl alcohol extracts of Cinnnamomum zylanicum, Cuminum cyminum, Curcuma long Linn, Trachyspermum ammi and selected standard antibiotics were investigated for their in vitro antibacterial activity against six human bacterial pathogens. The antibacterial activity was evaluated and based on the zone of inhibition using agar disc diffusion method. The tested bacterial strains were Streptococcus pyogenes, Staphylococcus epidermidis, Klebsiella pneumonia, Staphylococcus aurues, Serratia marcesnces, and Pseudomonas aeruginosa. Ciprofloxacin showed highly significant action against K. pneumonia and S. epidermidis while Ampicillin and Amoxicillin indicated lowest antibacterial activity against tested pathogens. Among the plants chloroform and isoamyl alcohol extracts of C. cyminum, S. aromaticum and C. long Linn had significant effect against P. aeruginosa, S. marcesnces and S. pyogenes. Comparison of antibacterial activity of medicinal herbs and standard antibiotics was also recorded via activity index. Used medicinal plants have various phytochemicals which reasonably justify their use as antibacterial agent.
authors.affiliation: Biotechnology Lab, Department of Zoology, Azad Jammu and Kashmir University, Muzaffarabad, Pakistan.
authors.forename: Uzma Azeem
authors.initials: UA
authors.lastname: Awan
authors.forename: Saiqa
authors.initials: S
authors.lastname: Andleeb
authors.forename: Ayesha
authors.initials: A
authors.lastname: Kiyani
authors.forename: Atiya
authors.initials: A
authors.lastname: Zafar
authors.forename: Irsa
authors.initials: I
authors.lastname: Shafique
authors.forename: Nazia
authors.initials: N
authors.lastname: Riaz
authors.forename: Muhammad Tehseen
authors.initials: MT
authors.lastname: Azhar
authors.forename: Hafeez
authors.initials: H
authors.lastname: Uddin
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts