title: Biomimetic artificial ion channels based on beta-cyclodextrin.
abstract: Star polymers based on β-cyclodextrin were synthesized by a ''click-chemistry'' process and characterized by NMR, SEC and BLM. The resulting triazole functional groups create, at a specific pH range, electrostatic hindrance between pores inserted in lipid bilayers, preventing their aggregation, allowing formation of well-defined isolated unitary pores and mimicking biological natural channels.
authors.affiliation: LAMBE, UMR8587, UEVE-CNRS-CEA, Bld François Mitterrand, 91025 Evry, France. cecile.huin@univ-evry.fr.
authors.forename: Yassine
authors.initials: Y
authors.lastname: El Ghoul
authors.forename: Ruddy
authors.initials: R
authors.lastname: Renia
authors.forename: Ibrahima
authors.initials: I
authors.lastname: Faye
authors.forename: Soumassoudrane
authors.initials: S
authors.lastname: Rassou
authors.forename: Nezha
authors.initials: N
authors.lastname: Badi
authors.forename: Véronique
authors.initials: V
authors.lastname: Bennevault-Celton
authors.forename: Cécile
authors.initials: C
authors.lastname: Huin
authors.forename: Philippe
authors.initials: P
authors.lastname: Guégan
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D032701:Biomimetics; D057930:Click Chemistry; D007473:Ion Channels / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry; D055672:Static Electricity; D014230:Triazoles / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D007473:Ion Channels; D008051:Lipid Bilayers; D014230:Triazoles; D047392:beta-Cyclodextrins; C031215:betadex