title: Quantification of finger joint loadings using musculoskeletal modelling clarifies mechanical risk factors of hand osteoarthritis.
abstract: Owing to limited quantitative data related to the loadings (forces and pressures) acting upon finger joints, several clinical observations regarding mechanical risk factors of hand osteoarthritis remain misunderstood. To improve the knowledge of this pathology, the present study used musculoskeletal modelling to quantify the forces and pressures acting upon hand joints during two grasping tasks. Kinematic and grip force data were recorded during both a pinch and a power grip tasks. Three-dimensional magnetic resonance imaging measurements were conducted to quantify joint contact areas. Using these datasets as input, a musculoskeletal model of the hand and wrist, including twenty-three degrees of freedom and forty-two muscles, has been developed to estimate joint forces and joint pressures. When compared with the power grip task, the pinch grip task resulted in two to eight times higher joint loadings whereas the grip forces exerted on each finger were twice lower. For both tasks, joint forces and pressures increased along a disto-proximal direction for each finger. The quantitative dataset provided by the present hand model clarified two clinical observations about osteoarthritis development which were not fully understood, i.e., the strong risk associated to pinch grip tasks and the high frequency of thumb-base osteoarthritis.
authors.affiliation: Aix-Marseille Université, CNRS, ISM UMR 7287, 13288 Marseille cedex 09, France. Electronic address: benjamin.demonsabert@gmail.com.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Goislard de Monsabert
authors.affiliation: Aix-Marseille Université, CNRS, ISM UMR 7287, 13288 Marseille cedex 09, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Vigouroux
authors.affiliation: Aix-Marseille Université, CNRS, CRMBM UMR 7339, 13005 Marseille, France.
authors.forename: David
authors.initials: D
authors.lastname: Bendahan
authors.affiliation: Aix-Marseille Université, CNRS, ISM UMR 7287, 13288 Marseille cedex 09, France.
authors.forename: Eric
authors.initials: E
authors.lastname: Berton
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D005384:Finger Joint / Q000502:physiology* / Q000503:physiopathology; D006225:Hand; D018737:Hand Strength / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008954:Models, Biological; D009132:Muscles / Q000502:physiology* / Q000503:physiopathology; D010003:Osteoarthritis / Q000503:physiopathology*; D011312:Pressure; D012307:Risk Factors; D016474:Weight-Bearing; D055815:Young Adult
keywords: Hand; Joint pressure; Musculoskeletal modelling; Osteoarthritis; Pinch grip; Power grip