title: Responsive lanthanide coordination polymer for hydrogen sulfide.
abstract: Metal organic coordination polymers have received great attention because of their flexible compositions and architecture. Here, we report the design and synthesis of a responsive lanthanide coordination polymer (LCP) for hydrogen sulfide (H2S), utilizing self-assembling of biomolecule nucleotide with luminescent terbium ion (Tb(3+)) and sensitizing silver ion (Ag(+)) in aqueous solution. LCP is highly fluorescent due to the inclusion of Ag(+) ions, which sensitized the fluorescence of Tb(3+) ions. H2S can strongly quench the fluorescence of LCP through its high affinity for Ag(+) ions. Such configurated LCP material from initial building blocks showed high sensitivity and selectivity for H2S and was applied to the determination of H2S in human serum. LCP with Tb(3+) ions also has a long fluorescence lifetime, which allows for time-resolved fluorescence assays, possessing particular advantages to probing H2S in biological systems with autofluorescence.
authors.affiliation: State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University , Nanjing, 210096, People's Republic of China.
authors.forename: Baoxia
authors.initials: B
authors.lastname: Liu
authors.forename: Yang
authors.initials: Y
authors.lastname: Chen
mesh_terms: D005453:Fluorescence; D006801:Humans; D006862:Hydrogen Sulfide / Q000097:blood* / Q000737:chemistry*; D028581:Lanthanoid Series Elements / Q000737:chemistry* / Q000378:metabolism; D011108:Polymers / Q000138:chemical synthesis* / Q000378:metabolism; D012834:Silver / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013725:Terbium / Q000737:chemistry
chemical_list: D028581:Lanthanoid Series Elements; D011108:Polymers; D013725:Terbium; D012834:Silver; D006862:Hydrogen Sulfide