title: The retreatment of carboplatin via high-dose intraperitoneal chemotherapy in patients with a history of a hypersensitivity reaction.
abstract: A hypersensitivity reaction attributed to platinum-based chemotherapy is a relatively common occurrence. Hyperthermic intraperitoneal chemotherapy potentially facilitates the safe retreatment of platinum therapy following this complication. We describe 3 ovarian cancer patients who were successfully retreated with carboplatin via hyperthermic intraperitoneal chemotherapy following hypersensitivity reaction.
authors.affiliation: Gynecologic Oncology Associates, Newport Beach, CA.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Rettenmaier
authors.affiliation: Gynecologic Oncology Associates, Newport Beach, CA.
authors.forename: Crystal M
authors.initials: CM
authors.lastname: Gray
authors.affiliation: Women's Cancer Research Foundation, Newport Beach, CA.
authors.forename: Katrina L
authors.initials: KL
authors.lastname: Lopez
authors.affiliation: Gynecologic Oncology Associates, Newport Beach, CA.
authors.forename: Karen A
authors.initials: KA
authors.lastname: Bechtol
authors.affiliation: Gynecologic Oncology Associates, Newport Beach, CA. Electronic address: bram@gynoncology.com.
authors.forename: Bram H
authors.initials: BH
authors.lastname: Goldstein
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D016190:Carboplatin / Q000008:administration & dosage* / Q000009:adverse effects; D003131:Combined Modality Therapy; D004342:Drug Hypersensitivity / Q000517:prevention & control; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D007263:Infusions, Parenteral / Q000379:methods; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy*; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000601:surgery; D019233:Retreatment
chemical_list: D000970:Antineoplastic Agents; D016190:Carboplatin
keywords: carboplatin; gynecologic oncology; hypersensitivity reactions; hyperthermic intraperitoneal chemotherapy