title: Ehlers-Danlos Syndrome Type VIII: A Rare Cause of Leg Ulcers in Young Patients.
abstract: Ehlers-Danlos syndrome type VIII (EDS-VIII) is a very rare autosomal dominant disease characterized by early-onset periodontitis associated with features of Ehlers-Danlos syndrome. We report a 32-year-old man whose chronic leg ulcer led to the diagnosis of EDS-VIII. He had severe periodontitis with complete loss of permanent teeth and skin fragility with thin skin, atrophic scars, and brownish atrophic pretibial plaques. Leg ulcer is not a prominent feature of EDS-VIII. We suggest adding EDS-VIII to the list of rare diseases accounting for chronic leg ulcers, if this case report prompts others to report leg ulcers associated with EDS-VIII.
authors.affiliation: Department of Dermatology, Pontchaillou University Hospital, 2 Rue Henri Le Guilloux, 35033 Rennes, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Ronceray
authors.forename: Juliette
authors.initials: J
authors.lastname: Miquel
authors.forename: Antoine
authors.initials: A
authors.lastname: Lucas
authors.forename: Gérald E
authors.initials: GE
authors.lastname: Piérard
authors.forename: Trinh
authors.initials: T
authors.lastname: Hermanns-Lê
authors.forename: Anne
authors.initials: A
authors.lastname: De Paepe
authors.forename: Alain
authors.initials: A
authors.lastname: Dupuy