title: Career perspective: John W. Severinghaus.
abstract: After training in physics during World War II, I spent 2 years designing radar at Massachusetts Institute of Technology and then switched to biophysics. After medical school and a residency, I was doctor drafted to National Institutes of Health where I studied blood gas transport in hypothermia and developed the carbon dioxide electrode and the blood gas analyzer (pH, partial pressure of O2, and partial pressure of CO2). I joined the University of California San Francisco in 1958 in a new anesthesia department and new Cardiovascular Research Institute. My research aims were anesthesia patient monitoring, respiratory physiology, blood gas transport, and high-altitude acclimatization and pathology.
authors.affiliation: University of California San Francisco, San Francisco, CA 94607, USA.
authors.forename: John W
authors.initials: JW
authors.lastname: Severinghaus
keywords: Acclimatization; Altitude; Anesthesia; Blood gas analysis; CO2 electrode; Cerebral blood flow; Monitor; Oximetry; Oxygen dissociation curve; Regulation of respiration