title: Mutant Gene snm2-1 (ts), conferring thermoconditional mutagen sensitivity in Saccharomyces cerevisiae, is allelic with RAD5.
abstract: Of two mutant genes (snm1-2 (ts) and snm2-1 (ts)) conferring thermoconditional mutagen sensitivity in Saccharomyces cerevisiae one (snm2-1 (ts)) is shown to be centromere-linked. At the restrictive temperature this allele reduces UV-induced back mutation frequency of the ochre allele hiss-2 but has no influence on forward mutation at the CAN1 locus. Complementation tests and recombination analysis revealed snm2 (ts) to be allelic with rad5 (rev2).
authors.affiliation: Institut für Mikrobiologie, Johann Wolfgang Goethe-Universität, Theodor-Stern -Kai 7, Haus 75, 6000, Frankfurt/M., Germany.
authors.forename: W
authors.initials: W
authors.lastname: Siedel
authors.forename: M
authors.initials: M
authors.lastname: Brendel