title: Endocervical-like versus intestinal-type mucinous borderline ovarian tumors: a large retrospective series focusing on the clinicopathologic characteristics.
abstract: OBJECTIVE
  To evaluate the clinical and pathologic features of patients with mucinous borderline tumor (MBT) of the ovary with special emphasis on the endocervical-like (EMBT) and intestinal-type (IMBT).
  
  
  METHODS
  This is a retrospective review of patients with MBT who were diagnosed and treated between 1995 and 2009 at a single institution. The records were analyzed for the patients' clinicopathologic information. The survival rates were calculated using the Kaplan-Meier method.
  
  
  RESULTS
  Of a total of 203 patients with MBT, there were 56 (27.6%) with EMBTs and 147 (72.4%) with IMBTs. Patients with EMBTs were significantly more asymptomatic (58.9%), had higher CA125 and CA19-9 levels, larger tumors (mean 17.3 cm), less frequent bilateral occurrence (5.4%), and less relation to endometriosis (1.4%), compared with those with IMBTs (all p < 0.05). During the median follow-up of 57.3 months (range 6-158), a total of 8 recurrences were identified: 6 were borderline and 2 were invasive lesion. With regard to the recurrence, EMBT and IMBT showed a 7-year recurrence-free survival rate of 97.1 and 92.1%, respectively, with no significant difference.
  
  
  CONCLUSIONS
  EMBT and IMBT had different clinicopathological profiles, although the histologic distinction of MBT was not associated with the prognosis.
authors.affiliation: Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, Republic of Korea.
authors.forename: Taejong
authors.initials: T
authors.lastname: Song
authors.forename: Chel Hun
authors.initials: CH
authors.lastname: Choi
authors.forename: Yoo-Young
authors.initials: YY
authors.lastname: Lee
authors.forename: Tae-Joong
authors.initials: TJ
authors.lastname: Kim
authors.forename: Jeong-Won
authors.initials: JW
authors.lastname: Lee
authors.forename: Chang Ohk
authors.initials: CO
authors.lastname: Sung
authors.forename: Sang Yong
authors.initials: SY
authors.lastname: Song
authors.forename: Duk-Soo
authors.initials: DS
authors.lastname: Bae
authors.forename: Byoung-Gie
authors.initials: BG
authors.lastname: Kim
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology* / Q000601:surgery; D000328:Adult; D018394:CA-125 Antigen / Q000032:analysis; D018395:CA-19-9 Antigen / Q000032:analysis; D002584:Cervix Uteri / Q000473:pathology; D005260:Female; D006801:Humans; D007422:Intestines / Q000473:pathology; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate
chemical_list: D018394:CA-125 Antigen; D018395:CA-19-9 Antigen