title: AC/D(eA)C rocks the polymerases.
abstract: In this issue of Molecular Cell, two studies (Chen et al., 2013; Schröder et al., 2013) describe how posttranslational modification of RNA polymerases (Pol) I and II by acetylation mediates the transcriptional response to either stress or growth factors.
authors.affiliation: Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
authors.forename: Clélia
authors.initials: C
authors.lastname: Laitem
authors.forename: Shona
authors.initials: S
authors.lastname: Murphy
mesh_terms: D000818:Animals; D006657:Histones / Q000235:genetics*; D006801:Humans; D008239:Lysine / Q000235:genetics*; D012318:RNA Polymerase I / Q000235:genetics*; D012319:RNA Polymerase II / Q000378:metabolism*; D037761:Sirtuins / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism*; D014158:Transcription, Genetic; D015533:Transcriptional Activation / Q000235:genetics*
chemical_list: D006657:Histones; C099638:POLR1E protein, human; C510661:SIRT7 protein, human; D014157:Transcription Factors; D012319:RNA Polymerase II; D012318:RNA Polymerase I; D037761:Sirtuins; D008239:Lysine