title: An unusual case of pulmonary granulocytic sarcoma treated with combined chemotherapy and radiation.
abstract: We report an unusual case of a 6-year-old male child who presented with fever and a cough of one month's duration. A bone marrow aspiration and cytogenetics were suggestive of acute myeloid leukaemia with t(8;21)(q22;q22). A chest x-ray and computed tomography of the thorax showed a soft tissue lesion in the right lung. The fine needle aspiration cytology (FNAC) of this lesion was suggestive of pulmonary granulocytic sarcoma. The patient was successfully treated with induction chemotherapy (cytosine arabinoside + daunomycin), followed by consolidation with high-dose cytosine arabinoside. In view of the persistent lesion in the right lung, the patient was given external beam radiotherapy (EBRT), which resulted in near total resolution of the lung granulocytic sarcoma. We report this case in view of its rarity and clinical importance, and to highlight the treatment options in this scenario.
authors.affiliation: Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, Karnataka 560029, India.
authors.forename: Vishwanath
authors.initials: V
authors.lastname: Sathyanarayanan
authors.forename: Nagesh Taterao
authors.initials: NT
authors.lastname: Sirsath
authors.forename: Umesh
authors.initials: U
authors.lastname: Das
authors.forename: M
authors.initials: M
authors.lastname: Malathi
authors.forename: Suma Lakshmipathi
authors.initials: SL
authors.lastname: Reddy
authors.forename: Kavitha S
authors.initials: KS
authors.lastname: Srivatsa
authors.forename: Avinash
authors.initials: A
authors.lastname: Thumallapalli
authors.forename: L
authors.initials: L
authors.lastname: Appaji
authors.forename: Bs Aruna
authors.initials: BA
authors.lastname: Kumari
keywords: chemotherapy; granulocytic sarcoma; pulmonary; radiation