title: Effect of "yang-warming and kidney essence-replenishing" herbal paste on cold-related asthma exacerbation.
abstract: OBJECTIVE
  To observe the effect of "Yang-warming and kidney essence-replenishing" herbal paste on cold-related asthma exacerbation.
  
  
  METHODS
  One hundred and fifty one patients with moderate to severe persistent asthma were randomly divided into a treatment group (n = 74) and a control group (n = 69). Both groups were given basic treatment according to the Global Initiative for Asthma scheme. The treatment group was also treated with herbal paste in the winter. The frequency of asthma exacerbation, cold and cold-related asthma exacerbation, scores of the asthma control test (ACT), and kidney-deficiency syndrome during the one-year follow-up in each group were recorded.
  
  
  RESULTS
  Compared with the control group, the onset frequencies of catching cold, asthma exacerbation, cold-related asthma exacerbation, and kidney-deficiency syndrome score were significantly reduced. There was no significant difference in scores of ACT between the two groups.
  
  
  CONCLUSIONS
  "Yang-warming and kidney essence-replenishing" herbal paste could reduce cold-related asthma exacerbation.
authors.affiliation: Emergency Department, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
authors.forename: Binqing
authors.initials: B
authors.lastname: Tang
authors.forename: Kehua
authors.initials: K
authors.lastname: Shi
authors.forename: Xiaoqi
authors.initials: X
authors.lastname: Li
authors.forename: Hongchang
authors.initials: H
authors.lastname: Wang
authors.forename: Hong
authors.initials: H
authors.lastname: Fang
authors.forename: Bidan
authors.initials: B
authors.lastname: Xiong
authors.forename: Yingen
authors.initials: Y
authors.lastname: Wu
mesh_terms: D000328:Adult; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007668:Kidney / Q000187:drug effects / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009824:Ointments / Q000008:administration & dosage*
chemical_list: D004365:Drugs, Chinese Herbal; D009824:Ointments