title: Identification of chemical hazards for terrestrial plants in the regulatory context: comparison of OECD and ISO guidelines.
abstract: Standardized test protocols are used in the regulatory context for identifying the hazardous properties of chemicals, wastes, and contaminated materials. This paper compares the relevance of two guidelines measuring effects on terrestrial plants, the OECD TG 208 and the ISO TG 22030 and presents the scientific basis for a recent decision of the European Chemicals Agency (ECHA) under the European chemicals regulation REACH. If there are no specific phytotoxicity alerts, both guidelines are considered suitable for assessing long-term hazards, providing that a sufficient number of species is included in the OECD protocol, the recommended minimum number is six, which offer a reasonably broad selection of species to account for interspecies sensitivity. The proposed methodology, based on a combination of probabilistic assessments using Monte Carlo analysis, can be adapted for supporting similar decisions under specific regulatory processes; for example, for assessing contaminated soils or pesticides' applications.
authors.forename: Jose V
authors.initials: JV
authors.lastname: Tarazona
authors.forename: Romanas
authors.initials: R
authors.lastname: Cesnaitis
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Herranz-Montes
authors.forename: Bram
authors.initials: B
authors.lastname: Versonnen
mesh_terms: D058735:Environmental Policy; D004787:Environmental Pollution / Q000331:legislation & jurisprudence*; D015386:Hazardous Substances / Q000592:standards / Q000633:toxicity*; D010944:Plants / Q000187:drug effects*; D012989:Soil Pollutants / Q000592:standards / Q000633:toxicity*
chemical_list: D015386:Hazardous Substances; D012989:Soil Pollutants