title: Detection of serious complications by MR imaging in asymptomatic young adults with repaired coarctation of the aorta.
abstract: BACKGROUND
  Despite early repair, patients with aortic coarctation (CoA) continue to have a reduced life expectancy due to the development of late complications. We sought to define the rate of aortic abnormalities in patients with previous CoA repair, referred for surveillance magnetic resonance (MR) imaging.
  
  
  METHODS
  We evaluated 59 asymptomatic adults consecutively for repaired CoA with MR imaging between 2008 and 2012.
  
  
  RESULTS
  Patients were aged 29 ± 8 (16-49) years; 34 males (58%) and 34 with bicuspid aortic valve (58%). Median age at the time of initial repair was two years. Surveillance MR imaging was performed 23 ± 8 years post-procedure. The three most common interventions performed were subclavian-flap repair (25%), end-to-end repair (33%) and patch aortoplasty (33%). Re-intervention with balloon angioplasty or repeat surgery had been performed in 22% of subjects. There were 28 cases of recoarctation (48%), of which seven were at least moderate in severity. Repair site and ascending aortic aneurysm occurred in eight (14%) and four (7%) subjects, respectively. Freedom from any degree of recoarctation and other aortic complications was observed in eight subjects (14%).
  
  
  CONCLUSIONS
  MR imaging detected a high rate of aortic abnormalities in asymptomatic adults after CoA repair, including 27% with clinically significant recoarctation and/or local aneurysm formation.
authors.affiliation: Agnes Ginges Centre for Molecular Cardiology, Centenary Institute, Australia; Sydney Medical School, University of Sydney, Australia; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia; The Baird Institute of Applied Heart and Lung Surgical Research, Sydney, Australia.
authors.forename: Ratnasari
authors.initials: R
authors.lastname: Padang
authors.affiliation: Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia.
authors.forename: Mark
authors.initials: M
authors.lastname: Dennis
authors.affiliation: Agnes Ginges Centre for Molecular Cardiology, Centenary Institute, Australia; Sydney Medical School, University of Sydney, Australia; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia.
authors.forename: Christopher
authors.initials: C
authors.lastname: Semsarian
authors.affiliation: Sydney Medical School, University of Sydney, Australia; The Baird Institute of Applied Heart and Lung Surgical Research, Sydney, Australia; Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia.
authors.forename: Paul G
authors.initials: PG
authors.lastname: Bannon
authors.affiliation: Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia; Department of Cardiology, Westmead Hospital, Sydney, Australia.
authors.forename: David J
authors.initials: DJ
authors.lastname: Tanous
authors.affiliation: Sydney Medical School, University of Sydney, Australia; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia.
authors.forename: David S
authors.initials: DS
authors.lastname: Celermajer
authors.affiliation: Sydney Medical School, University of Sydney, Australia; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia; SMRI, RPAH Medical Centre, Australia. Electronic address: raj.puranik@cmrs.org.au.
authors.forename: Rajesh
authors.initials: R
authors.lastname: Puranik
mesh_terms: D000293:Adolescent; D000328:Adult; D001014:Aortic Aneurysm / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D001017:Aortic Coarctation / Q000000981:diagnostic imaging / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D011859:Radiography; D012189:Retrospective Studies; D055815:Young Adult
keywords: Aneurysm; Aorta; Coarctation of the aorta; Congenital heart defects; Magnetic resonance imaging; Recoarctation