title: "Sisters, Mothers, Daughters and Aunties": HIV vaccine acceptability among African, Caribbean and other Black women in Toronto.
abstract: OBJECTIVE
  Black women in Canada are at disproportionately high risk for HIV. We assessed HIV vaccine acceptability and correlates of acceptability among Black women from African and Caribbean communities in Toronto.
  
  
  METHODS
  "Sisters, Daughters, Mothers, and Aunties" was a community-based research project. Black women of African and Caribbean descent were recruited using venue-based sampling across diverse community organizations in Toronto. We used a structured questionnaire to collect data on socio-demographic characteristics and acceptability of 8 future HIV vaccines, each defined by a set of 7 dichotomous attributes. Conjoint analysis was used to quantify the relative impact of vaccine attributes on acceptability, with multiple regression to adjust for socio-demographic characteristics associated with overall acceptability.
  
  
  RESULTS
  Mean vaccine acceptability was 58.8 (SD=17.2) on the 100-point scale. Efficacy had the greatest impact on acceptability, followed by side effects, cost, duration of protection, and number of doses. Acceptability of a high (99%) efficacy vaccine (70.1/100) was significantly greater than for a 50% efficacy vaccine (47.6/100). Vaccine acceptability was significantly higher among women of Caribbean versus African descent, ever married versus single women, and women with full-time versus part-time employment.
  
  
  CONCLUSIONS
  Black women in Toronto indicated a modest level of acceptability for future HIV vaccines. Educational interventions that address the benefits of partially efficacious vaccines and clearly explain potential side effects, as well as vaccine cost subsidies may promote HIV vaccine uptake. Differences in acceptability within Black communities suggest that tailored multi-level interventions may mitigate barriers to uptake.
authors.affiliation: University of Toronto. p.newman@utoronto.ca.
authors.forename: James
authors.initials: J
authors.lastname: Weaver
authors.forename: Peter A
authors.initials: PA
authors.lastname: Newman
authors.forename: Charmaine C
authors.initials: CC
authors.lastname: Williams
authors.forename: Notisha
authors.initials: N
authors.lastname: Massaquoi
authors.forename: Marsha
authors.initials: M
authors.lastname: Brown
mesh_terms: D016915:AIDS Vaccines / Q000008:administration & dosage*; D000328:Adult; D044383:Black People / Q000523:psychology* / Q000706:statistics & numerical data; D017691:Caribbean Region / Q000208:ethnology; D005260:Female; D015658:HIV Infections / Q000208:ethnology* / Q000517:prevention & control; D006801:Humans; D008875:Middle Aged; D009864:Ontario; D010342:Patient Acceptance of Health Care / Q000208:ethnology* / Q000706:statistics & numerical data; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D016915:AIDS Vaccines
keywords: AIDS vaccines; African; Canada; Caribbean and other Black women; acceptability of healthcare; conjoint analysis