title: Tandem isomerization/hydroformylation/hydrogenation of internal alkenes to n-alcohols using Rh/Ru dual- or ternary-catalyst systems.
abstract: A one-pot three-step reaction, isomerization/hydroformylation/hydrogenation of internal alkenes to n-alcohols, was accomplished by employing a Rh/Ru dual-catalyst system. By using a combination of Rh(acac)(CO)2/bisphosphite and Shvo's catalyst, (Z)-2-tridecene was converted to 1-tetradecanol in 83% yield with high normal/iso selectivity (n/i = 12). The method was applicable to other internal alkenes, including functionalized alkenes, such as an alkenol and an alkenoate. Furthermore, addition of a third component, Ru3(CO)12, effectively improved the n/i ratio in the tandem isomerization/hydroformylation/hydrogenation of methyl oleate (from n/i = 1.9 to 4.4). Control experiments revealed that the isomerization was mediated by both Rh and Ru and that the coexistence of Rh and Ru was essential for hydrogenation of aldehyde under H2/CO.
authors.affiliation: Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo , 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
authors.forename: Yamato
authors.initials: Y
authors.lastname: Yuki
authors.forename: Kohei
authors.initials: K
authors.lastname: Takahashi
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Kyoko
authors.initials: K
authors.lastname: Nozaki