title: Twenty-five years of progress: the view from NIMH and NINDS.
abstract: As directors of two NIH institutes supporting neuroscience research, we explore the gap between 25 years of stunning progress in fundamental neuroscience and the persistent needs of those with brain disorders. We conclude that closing this gap will require a more detailed comprehension of brain function, a rethinking of how we approach translational science, a focus on human neurobiology, and a continuing commitment to build a diverse, innovative neuroscience workforce. In contrast to many other areas of medicine, we lack basic knowledge about our organ of interest. The next phase of progress on brain disorders will require a significantly deeper understanding of fundamental neurobiology.
authors.affiliation: National Institute of Mental Health, 6001 Executive Boulevard, Room 8129, MSC 9669, Bethesda, MD 20892-9669, USA. Electronic address: tinsel@mail.nih.gov.
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Insel
authors.forename: Story C
authors.initials: SC
authors.lastname: Landis
mesh_terms: D000818:Animals; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D009315:National Institute of Mental Health (U.S.) / Q000266:history / Q000592:standards / Q000639:trends; D055825:National Institute of Neurological Disorders and Stroke (U.S.) / Q000266:history / Q000592:standards / Q000639:trends; D014481:United States