title: Bevacizumab-induced transient sixth nerve palsy in ovarian cancer: A case report.
abstract: We report a case of transient sixth nerve palsy after systemic administration of bevacizumab. Two days after systemic administration of bevacizumab in conjunction with gemcitabine and carboplatin in a 67-year-old woman with recurrent primary ovarian cancer, the patient developed sixth nerve palsy. After bevacizumab was stopped, the complete left sixth nerve palsy resolved spontaneously over the course of 3 months. This is the first reported case of bevacizumab-induced cranial sixth nerve palsy in the treatment of gynecologic malignancy.
authors.affiliation: Gynecology Oncology Division, Mount Sinai School of Medicine, New York, USA.
authors.forename: Mazdak
authors.initials: M
authors.lastname: Momeni
authors.affiliation: Gynecology Oncology Division, Mount Sinai School of Medicine, New York, USA.
authors.forename: Laura
authors.initials: L
authors.lastname: Veras
authors.affiliation: Gynecology Oncology Division, Mount Sinai School of Medicine, New York, USA.
authors.forename: Konstantin
authors.initials: K
authors.lastname: Zakashansky
mesh_terms: D020434:Abducens Nerve Diseases / Q000139:chemically induced*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D000068258:Bevacizumab / Q000008:administration & dosage / Q000009:adverse effects*; D016190:Carboplatin / Q000008:administration & dosage; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D000093542:Gemcitabine
chemical_list: D003841:Deoxycytidine; D000068258:Bevacizumab; D016190:Carboplatin; D000093542:Gemcitabine