title: Atypical antipsychotics in the treatment of posttraumatic stress disorder.
abstract: OBJECTIVE
  This study reviewed extant published articles on the efficacy and safety of atypical antipsychotics for the treatment of posttraumatic stress disorder (PTSD).
  
  
  METHODS
  We performed a literature search using PubMed, EMBASE, and the Cochrane database in January 2013. Selection criteria for this review included prospective, controlled studies using validated rating scales of PTSD symptoms in the management of PTSD.
  
  
  RESULTS
  A total of 12 prospective, controlled studies were included in this review. This review found that atypical antipsychotics are effective and safe in treating PTSD, although there were some negative findings. In particular, atypical antipsychotics also seem to be effective in treating anxiety, depression, and psychotic symptoms frequently accompanied by PTSD.
  
  
  CONCLUSIONS
  This review found that atypical antipsychotics seemed to be effective and tolerable in the management of PTSD, although the evidence was limited.
authors.affiliation: Department of Psychiatry, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
authors.forename: Hee Ryung
authors.initials: HR
authors.lastname: Wang
authors.forename: Young Sup
authors.initials: YS
authors.lastname: Woo
authors.forename: Won-Myong
authors.initials: WM
authors.lastname: Bahk
mesh_terms: D014150:Antipsychotic Agents / Q000627:therapeutic use*; D018849:Controlled Clinical Trials as Topic / Q000379:methods; D019317:Evidence-Based Medicine / Q000379:methods; D006801:Humans; D010879:Piperazines / Q000627:therapeutic use; D011446:Prospective Studies; D018967:Risperidone / Q000627:therapeutic use; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology*; D013844:Thiazoles / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D010879:Piperazines; D013844:Thiazoles; C092292:ziprasidone; D018967:Risperidone