title: AgOTf-catalyzed one-pot reactions of 2-alkynylbenzaldoximes with α,β-unsaturated carbonyl compounds.
abstract: AgOTf-catalyzed one-pot reactions of 2-alkynylbenzaldoximes with various α,β-unsaturated carbonyl compounds under mild conditions are described, which provides a facile and efficient pathway for the synthesis of 1-alkylated isoquinoline derivatives. The method tolerates a wide range of substrates and allows for the preparation of the products of interest in moderate to excellent yields.
authors.affiliation: Key Laboratory of Functional Small Organic Molecules, Ministry of Education and College of Chemistry & Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330022, P. R. China.
authors.forename: Qiuping
authors.initials: Q
authors.lastname: Ding
authors.forename: Dan
authors.initials: D
authors.lastname: Wang
authors.forename: Puying
authors.initials: P
authors.lastname: Luo
authors.forename: Meiling
authors.initials: M
authors.lastname: Liu
authors.forename: Shouzhi
authors.initials: S
authors.lastname: Pu
authors.forename: Liyun
authors.initials: L
authors.lastname: Zhou
keywords: 2-(isoquinolin-1-yl)ethanol; 2-alkynylbenzaldoxime; cyclization; rearrangement; α,β-unsaturated carbonyl compound