title: Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions.
abstract: Asymmetric alkylation reactions using non-cross-linked polystyrene (NCPS)-supported 2-imidazolidinone chiral auxiliaries were successfully investigated with excellent diastereocontrol (>99% de). The recovery and the recycling of this soluble polymer-supported chiral auxiliary were achieved in order to produce highly optical pure carboxylic acids.
authors.affiliation: School of Applied Chemistry and Center for Functional Nano Fine Chemicals, Chonnam National University, Gwangju 500-757, Republic of Korea.
authors.forename: Quynh Pham Bao
authors.initials: QP
authors.lastname: Nguyen
authors.forename: Taek Hyeon
authors.initials: TH
authors.lastname: Kim
keywords: 2-imidazolidinone; asymmetric alkylation; chiral auxiliaries; chiral carboxylic acids; non-cross-linked polystyrene