title: Effect of preloading epidural space with normal saline on the incidence of complications of epidural catheter placement and spinal anesthesia for cesarean section.
abstract: To evaluate the effect of preloading the epidural space with normal saline (NS) on the incidence of complications of epidural catheter placement and spinal anesthesia for cesarean section. Two hundred and ninety parturients at full term, who were scheduled for cesarean section under combined spinal-epidural anesthesia were randomly divided into two groups: group control (I) and group NS (II). The epidural puncture was performed at the estimated L3-4 interspace with a Tuohy needle attached to a 5 ml syringe. Loss of resistance to air was used to identify the epidural space. In group I no fluid was injected into the epidural space before insertion of the catheter; while in group II NS 5 ml was injected into the epidural space before catheter insertion. The incidence of blood vessel trauma and paraesthesia were evaluated. The effect of spinal anesthesia was evaluated. Blood vessel trauma in group II was significantly lower than in group I, P < 0.05. However, the incidence of paraesthesia was similar between the two groups, P > 0.05. Preloading the epidural space with NS can decrease the incidence of clinically apparent injury to blood vessels during epidural catheter placement, and can improve the effects of spinal analgesia, but does not reduce the incidence of paraesthesia.
authors.affiliation: Department of Anesthesiology, Obstetrics and Gynecology Hospital, Fudan University, Shenyang Road 128#, Yangpu District, Shanghai, 200090, China, mzgengguiqi@163.com.
authors.forename: Guiqi
authors.initials: G
authors.lastname: Geng
authors.forename: Xingfeng
authors.initials: X
authors.lastname: Sun
authors.forename: Shaoqiang
authors.initials: S
authors.lastname: Huang
mesh_terms: D000328:Adult; D000767:Anesthesia, Epidural / Q000379:methods / Q000706:statistics & numerical data*; D000775:Anesthesia, Spinal / Q000379:methods / Q000706:statistics & numerical data*; D002406:Catheterization, Peripheral / Q000379:methods / Q000706:statistics & numerical data*; D015984:Causality; D002585:Cesarean Section / Q000379:methods / Q000706:statistics & numerical data*; D002681:China / Q000453:epidemiology; D015897:Comorbidity; D004824:Epidural Space; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010292:Paresthesia / Q000453:epidemiology*; D011247:Pregnancy; D012307:Risk Factors; D012965:Sodium Chloride / Q000008:administration & dosage*; D016896:Treatment Outcome; D057772:Vascular System Injuries / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D012965:Sodium Chloride