title: Imaging the seizure during surgery with a hyperspectral camera.
abstract: An epilepsy patient with recurring sensorimotor seizures involving the left hand every 10 min, was imaged with a hyperspectral camera during surgery. By calculating the changes in oxygenated, deoxygenated blood, and total blood volume in the cortex, a focal increase in oxygenated and total blood volume could be observed in the sensory cortex, corresponding to the seizure-onset zone defined by intracranial electroencephalography (EEG) findings. This probably reflects very local seizure activity. After multiple subpial transections in this motor area, clinical seizures abated.
authors.affiliation: Department of Medical Technology & Clinical Physics, University Medical Center Utrecht, Utrecht, The Netherlands.
authors.forename: Herke Jan
authors.initials: HJ
authors.lastname: Noordmans
authors.forename: Cyrille
authors.initials: C
authors.lastname: Ferrier
authors.forename: Rowland
authors.initials: R
authors.lastname: de Roode
authors.forename: Frans
authors.initials: F
authors.lastname: Leijten
authors.forename: Peter
authors.initials: P
authors.lastname: van Rijen
authors.forename: Peter
authors.initials: P
authors.lastname: Gosselaar
authors.forename: John
authors.initials: J
authors.lastname: Klaessens
authors.forename: Ruud
authors.initials: R
authors.lastname: Verdaasdonk
mesh_terms: D000293:Adolescent; D001931:Brain Mapping / Q000379:methods; D004569:Electroencephalography / Q000379:methods; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D009044:Motor Cortex / Q000098:blood supply / Q000503:physiopathology / Q000601:surgery*; D012640:Seizures / Q000097:blood / Q000175:diagnosis / Q000601:surgery*; D016896:Treatment Outcome
keywords: Epilepsy surgery; Hyperspectral imaging; Ictal hyperperfusion