title: Cholestatic jaundice as a paraneoplastic manifestation of prostate cancer.
abstract: Paraneoplastic syndrome associated with prostate cancer is extremely rare. We report a patient who presented with cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection. After a few detailed examinations, prostate cancer was diagnosed. After treatment with bicalutamide and leuprolide, the patient's symptoms and laboratory abnormalities were reversed. Cholestatic jaundice was regarded as a paraneoplastic manifestation in this patient. The patient remains symptom-free after 14-month followup. Paraneoplastic syndrome should be considered in case of cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection.
authors.affiliation: Department of Urology, Social Insurance Kinan Hospital, 46-70 Shinjou-chou, Tanabe-shi, Wakayama 646-8588, Japan.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Kuramoto
authors.forename: Hiroya
authors.initials: H
authors.lastname: Senzaki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Koike
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamagiwa
authors.forename: Shinobu
authors.initials: S
authors.lastname: Tamura
authors.forename: Tokuzou
authors.initials: T
authors.lastname: Fujimoto
authors.forename: Takeshi
authors.initials: T
authors.lastname: Inagaki