title: Ruthenium-catalyzed C-H functionalization of arylpyrazoles: regioselective acylation with acid chlorides.
abstract: A ruthenium-catalyzed C-H acylation of arylpyrazoles with a variety of acyl chlorides is described. The acylation reaction exhibits good regioselectivity and both aromatic and aliphatic acyl chlorides can be effectively coupled to the arylpyrazoles at the ortho-position.
authors.affiliation: Department of Chemistry, University of Bath , Bath, BA2 7AY, U.K.
authors.forename: Po Man
authors.initials: PM
authors.lastname: Liu
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Frost
mesh_terms: D000215:Acylation; D002384:Catalysis; D006851:Hydrochloric Acid / Q000737:chemistry*; D015394:Molecular Structure; D011720:Pyrazoles / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D011720:Pyrazoles; D012428:Ruthenium; D006851:Hydrochloric Acid