title: [Vitamin D and the skin].
abstract: Vitamin D is well known for its beneficial effects on phosphocalcic homeostasis. The discovery of the role of vitamin D in cancers, infections, cardiovascular or autoimmune pathologies have promoted interest for this molecule. Skin and vitamin D are closely related. The skin is not only the site of vitamin D synthesis, but also a target organ as calcitriol plays an important hormonal and regulatory role, acting on cell proliferation, differentiation and immunomodulation. Furthermore, vitamin D influences the incidence and therapeutic response of certain dermatoses. In addition, many medical situations, mainly dermatological, require strict photoprotection and may therefore indirectly be responsible for a vitamin D deficiency in patients. The current role of vitamin D in skin cancers, inflammatory and autoimmune skin diseases is summarized.
authors.affiliation: Service de Dermatologie, CHU de Liège.
authors.forename: F
authors.initials: F
authors.lastname: Libon
authors.forename: E
authors.initials: E
authors.lastname: Cavalier
authors.forename: A F
authors.initials: AF
authors.lastname: Nikkels
mesh_terms: D002280:Basal Cell Carcinoma / Q000150:complications / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D006801:Humans; D008545:Melanoma / Q000150:complications / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D012867:Skin / Q000378:metabolism / Q000473:pathology; D012878:Skin Neoplasms / Q000150:complications / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D012879:Skin Physiological Phenomena; D014807:Vitamin D / Q000378:metabolism / Q000502:physiology*; D014808:Vitamin D Deficiency / Q000150:complications / Q000453:epidemiology / Q000378:metabolism / Q000628:therapy
chemical_list: D014807:Vitamin D