title: Plasma coenzyme Q10 levels in type 2 diabetic patients with retinopathy.
abstract: OBJECTIVE
  To determine the relationship between proliferative diabetic retinopathy (PDRP) and plasma coenzyme Q10(CoQ10) concentration.
  
  
  METHODS
  Patients with type 2 diabetes and PDRP were determined to be the case group (n=50). The control group was consist of healthy individuals (n=50). Plasma CoQ10 and malondialdehyde (MDA) levels were measured in both groups.
  
  
  RESULTS
  Ubiquinone-10 (Coenzyme Q10) levels in PDRP and control subjects are 3.81±1.19µmol/L and 1.91±0.62µmol/L, respectively. Plasma MDA levels in PDRP and control subjects were 8.16±2µmol/L and 3.44±2.08µmol/L, respectively. Ratio of Ubiquinol-10/ubiquinone-10 in PDRP and control subjects were 0.26±0.16 and 1.41±0.68, respectively.
  
  
  CONCLUSIONS
  The ratio of ubiquinol-10/ubiquinone-10 is found lower in patients with PDRP. High levels of plasma ubiquinol-10/ubiquinone-10 ratio indicate the protective effect on diabetic retinopathy.
authors.affiliation: Department of Ophthalmology, Medical School of Ataturk University, Erzurum 25240, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Ates
authors.forename: Habip
authors.initials: H
authors.lastname: Bilen
authors.forename: Sadullah
authors.initials: S
authors.lastname: Keles
authors.forename: H Hakan
authors.initials: HH
authors.lastname: Alp
authors.forename: Mevlüt Sait
authors.initials: MS
authors.lastname: Keleş
authors.forename: Kenan
authors.initials: K
authors.lastname: Yıldırım
authors.forename: Osman
authors.initials: O
authors.lastname: Ondaş
authors.forename: L Can
authors.initials: LC
authors.lastname: Pınar
authors.forename: Mustafa
authors.initials: M
authors.lastname: Civelekler
authors.forename: Orhan
authors.initials: O
authors.lastname: Baykal
keywords: coenzyme Q10; diabetic; retinopathy