title: Is surgery in the elderly for oesophageal cancer justifiable? Results from a single centre.
abstract: Aims. Advanced age is an identified risk factor for patients undergoing oncological surgical resection. The surgery for oesophageal cancer is associated with significant morbidity and mortality. Our aim was to study the operative management of elderly patients (≥70 years) at a single institute. Methods. The data was collected from 206 patients who have undergone operative resection of oesophageal cancer. The demographic, operative, histological, and postoperative follow-up of all patients were analysed. Results. A total of 46 patients of ≥70 years who had surgical resection for oesophageal cancer were identified. Patients ≥70 years had poor overall survival (P = 0.00). Also elderly patients with nodal involvement had poor survival (P = 0.04). Age at the time of surgery had no impact on the incidence of postoperative complication and inpatient mortality. Both the univariate and multivariate analyses showed age, nodal stage, and positive resection margins as independent prognostic factors for patients undergoing surgery for oesophageal cancer. Conclusions. Advanced age is associated with poor outcome following oesophageal resection. However, the optimisation of both preoperative and postoperative care can significantly improve outcomes. The decision of operative management should be individualised. Age should be considered as one of the factors in surgical resection of oesophageal cancer in the elderly patients.
authors.affiliation: Departments of Gastrointestinal Surgery and Histopathology, The University Hospital of South Manchester, SouthMoor Road, Wythenshawe, Manchester M23 9LT, UK.
authors.forename: A
authors.initials: A
authors.lastname: Mirza
authors.forename: S
authors.initials: S
authors.lastname: Pritchard
authors.forename: I
authors.initials: I
authors.lastname: Welch