title: Transplantation: Complementing donor-specific antibody testing.
abstract: New data suggest that among kidney transplant recipients, those whose serum contains donor-specific antibodies that bind C1q fare the worst. Although these findings are intriguing, several unanswered questions remain and changing practice to include a C1q binding assay as standard of care in kidney transplantation would be premature.
authors.affiliation: Department of Laboratory Medicine and Pathobiology, University Health Network HLA Laboratory, University of Toronto, 67 College Street, Room 301, Toronto, ON M5G 2M1, Canada.
authors.forename: Kathryn J
authors.initials: KJ
authors.lastname: Tinckam
authors.forename: Peter S
authors.initials: PS
authors.lastname: Heeger
mesh_terms: D000906:Antibodies / Q000378:metabolism*; D003165:Complement System Proteins / Q000378:metabolism*; D005260:Female; D006085:Graft Survival / Q000276:immunology*; D006680:HLA Antigens / Q000276:immunology*; D006801:Humans; D016030:Kidney Transplantation; D008297:Male
chemical_list: D000906:Antibodies; D006680:HLA Antigens; D003165:Complement System Proteins