title: Neuroimaging, cancer, and cognition: state of the knowledge.
abstract: OBJECTIVE
  To review neuroimaging research concerning cancer- and cancer treatment-related changes in brain structure and function, clinical perspectives, and future directions.
  
  
  METHODS
  Peer-reviewed literature.
  
  
  CONCLUSIONS
  Cancer and chemotherapy are associated with cerebral structural and functional alterations in breast cancer patients that may persist for years; many of these changes are correlated with cognitive complaints or performance. In other cancers there is some evidence that metabolism is altered by cancer, but more research is needed.
  
  
  CONCLUSIONS
  Understanding the role of neuroimaging is important to identify the basis of cognitive changes associated with cancer and cancer treatment.
authors.forename: Kelly N
authors.initials: KN
authors.lastname: Holohan
authors.forename: Diane
authors.initials: D
authors.lastname: Von Ah
authors.forename: Brenna C
authors.initials: BC
authors.lastname: McDonald
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Saykin
mesh_terms: D001932:Brain Neoplasms / Q000556:secondary; D001943:Breast Neoplasms / Q000473:pathology*; D003071:Cognition; D005260:Female; D006801:Humans
keywords: Cancer; cognition; neuroimaging; review