title: Hedgehog threads to spread.
abstract: In vivo time-lapse imaging and functional tests bring fresh evidence that the morphogen Hedgehog is conveyed to target cells via long filopodia extensions, dubbed cytonemes. This study provides the tools and conceptual framework to understand how cytonemes form and carry morphogens.
authors.affiliation: MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, UK.
authors.forename: James
authors.initials: J
authors.lastname: Briscoe
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Vincent
mesh_terms: D000818:Animals; D029721:Drosophila Proteins / Q000378:metabolism*; D053823:Hedgehog Proteins / Q000378:metabolism*
chemical_list: D029721:Drosophila Proteins; D053823:Hedgehog Proteins; C077245:hh protein, Drosophila