title: Open fractures of the hand with soft tissue loss.
abstract: The evaluation, initial treatment, and definitive reconstruction of open fractures of the hand with associated soft tissue loss are reviewed. Specific attention is given to the literature on open fracture antibiotic prophylaxis in the hand; the timing of bone and soft tissue reconstruction; and options for soft tissue coverage, including local, regional, and distant tissue transfer. Factors that have shown association with outcomes in these injuries are also discussed, and the authors' preferred management is summarized.
authors.affiliation: Department of Orthopaedic Surgery, University of Michigan, 2098 South Main Street, Ann Arbor, MI 48103, USA.
authors.forename: David
authors.initials: D
authors.lastname: Ruta
authors.forename: Kagan
authors.initials: K
authors.lastname: Ozer
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005597:Fractures, Open / Q000601:surgery*; D006801:Humans; D019651:Plastic Surgery Procedures; D017695:Soft Tissue Injuries / Q000601:surgery*; D013524:Surgical Flaps; D014946:Wound Infection / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents
keywords: Antibiotics; Flap; Fracture; Graft; Open; Primary; Reconstruction; Tissue