title: Imaging in osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma, and classic adamantinoma.
abstract: Fibro-osseous lesions of the bone are well-recognized primary bone tumours. However, given the degree of overlap of imaging findings and variation in management of various sub-types, it is a widely accepted practice to perform a biopsy to obtain histopathological confirmation of the diagnosis. The following is a summary of the epidemiology, clinicopathological features, and review of the imaging features of fibro-osseous lesions, including osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma, adamantinoma, and lesions that closely mimic them. The illustrated examples are histologically proven cases that were presented to a tertiary referral teaching hospital and national bone and soft-tissue tumours unit. It is important that all radiologists are aware of the nature and imaging characteristics of these tumour sub-types, so that suspected lesions are recognized and appropriately referred to specialist bone tumour services for work-up and management.
authors.affiliation: Department of Radiology, University Hospital of North Durham, County Durham and Darlington NHS Foundation Trust, Durham, UK. Electronic address: bethapudi@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Bethapudi
authors.affiliation: Department of Radiology, Western Infirmary, Greater Glasgow and Clyde Hospitals NHS Trust, Glasgow, UK.
authors.forename: D A
authors.initials: DA
authors.lastname: Ritchie
authors.affiliation: Department of Pathology, Western Infirmary, Greater Glasgow and Clyde Hospitals NHS Trust, Glasgow, UK.
authors.forename: E
authors.initials: E
authors.lastname: Macduff
authors.affiliation: Department of Radiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK.
authors.forename: J
authors.initials: J
authors.lastname: Straiton
mesh_terms: D050398:Adamantinoma / Q000175:diagnosis*; D000293:Adolescent; D000328:Adult; D001848:Bone Diseases, Developmental / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D011877:Radionuclide Imaging; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods; D055815:Young Adult