title: [Polymorphs of clopidogrel bisulfate].
abstract: This paper is to report the polymorphism of raw materials of clopidogrel bisulfate at home and abroad. By the analysis of Fourier transform infrared spectroscopy (FTIR) and powder X-ray diffraction (p-XRD), samples are roughly classified into two groups, except one patent material. And the differential scanning calorimeter (DSC) examination showed more detailed information for these materials. The results of the study could provide comprehensive basis for the quality evaluation of clopidogrel bisulfate.
authors.affiliation: National Institutes for Food and Drug Control, Beijing 100050, China. liuyi@nifdc.org.cn
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.forename: Hai-Wei
authors.initials: HW
authors.lastname: Huang
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Wu
authors.forename: Ya-Qin
authors.initials: YQ
authors.lastname: Shi
authors.forename: La-Hu
authors.initials: LH
authors.lastname: Yang
mesh_terms: D002152:Calorimetry, Differential Scanning; D000077144:Clopidogrel; D003460:Crystallization; D005069:Evaluation Studies as Topic; D010975:Platelet Aggregation Inhibitors / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine