title: In-patient discharge rates for the irritable bowel syndrome - an analysis of national trends in the United States from 1997 to 2010.
abstract: BACKGROUND
  Irritable bowel syndrome (IBS) is one of the most common out-patient diagnoses in primary care and gastroenterology. There are limited data on the rate and costs associated with in-patient discharges for IBS.
  
  
  OBJECTIVE
  To estimate the incidence and costs of hospital discharges for IBS in the United States.
  
  
  METHODS
  We analysed the National Inpatient Sample database for all subjects in which IBS (ICD-9 code: 564.1) was the principal discharge diagnosis from 1997 to 2010. The National Inpatient Sample contains data from approximately 8 million hospital stays each year. Our findings reflected patient and hospital characteristics like geographical region and bed size.
  
  
  RESULTS
  In 1997, there were 11 433 patients with a principal discharge diagnosis of IBS as compared to 12 842 in 2010 (P > 0.9, GoF test). The mean length of stay for IBS also remained the same between 1997 and 2010 at 3.7 ± 0.1 days. However, during this period, the mean hospital charges per hospitalization increased by 207.8% from $6873 ± 198 in 1997 to $21 153 ± 598 in 2010 (P < 0.01). The aggregate charges (i.e., 'national bill') for IBS increased by 245.5% from $78 524 129 ± 3 781 316 in 1997 to $271 311 405 ± 14 023 289 in 2010 (P < 0.01).
  
  
  CONCLUSIONS
  The number of in-patient discharges and length of stay for IBS have remained relatively stable between 1997 and 2010, whereas the cost associated with these discharges has increased significantly. In-patient costs associated with IBS contribute significantly to the total healthcare bill. Further research on the cost-effectiveness of diagnostic procedures and therapies in IBS is required.
authors.affiliation: Division of Gastroenterology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
authors.forename: S
authors.initials: S
authors.lastname: Sethi
authors.forename: V
authors.initials: V
authors.lastname: Wadhwa
authors.forename: J
authors.initials: J
authors.lastname: LeClair
authors.forename: S
authors.initials: S
authors.lastname: Mikami
authors.forename: R
authors.initials: R
authors.lastname: Park
authors.forename: M
authors.initials: M
authors.lastname: Jones
authors.forename: N
authors.initials: N
authors.lastname: Sethi
authors.forename: A
authors.initials: A
authors.lastname: Brown
authors.forename: A
authors.initials: A
authors.lastname: Lembo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D005260:Female; D017721:Hospital Costs / Q000706:statistics & numerical data; D006760:Hospitalization / Q000191:economics* / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007223:Infant; D043183:Irritable Bowel Syndrome / Q000191:economics* / Q000453:epidemiology; D007902:Length of Stay / Q000706:statistics & numerical data / Q000639:trends*; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge / Q000706:statistics & numerical data / Q000639:trends*; D014481:United States / Q000453:epidemiology; D055815:Young Adult