title: Biomimetic growth of bone-like apatite via simulated body fluid on hydroxyethyl cellulose/polyvinyl alcohol electrospun nanofibers.
abstract: In this study, randomly oriented hydroxyethyl cellulose/polyvinyl alcohol (HEC/PVA) nanofibers were fabricated by electrospinning. The blend solutions of HEC/PVA with different weight ratio of HEC to PVA were prepared using water as solvent to fabricate nanofibers. These nanofibrous scaffolds were coated with bone-like apatite by immersing into 10x simulated body fluid (SBF) for different time periods. The morphology and structure of the nanofibers were characterized by SEM, FTIR and DSC. FESEM-EDS and FTIR analysis were used to confirm the deposition of apatite on the surface of nanofibers. The results of this study suggest that this apatite coated nanofibrous scaffolds could be a suitable biomaterial for bone tissue engineering.
authors.forename: Sugandha
authors.initials: S
authors.lastname: Chahal
authors.affiliation: Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang, Lebuhraya Tun Razak, 26300 Gambang, Kuantan, Pahang, Malaysia.
authors.forename: Sugandha
authors.initials: S
authors.lastname: Chalal
authors.forename: Shahitha Jahir Hussain
authors.initials: SJ
authors.lastname: Fathima
authors.forename: Mashitah Binti Mohd
authors.initials: MB
authors.lastname: Yusoff
mesh_terms: D001031:Apatites / Q000737:chemistry*; D001672:Biocompatible Materials / Q000737:chemistry; D032701:Biomimetics; D001826:Body Fluids / Q000737:chemistry*; D001842:Bone and Bones; D002130:Calcium Phosphates / Q000737:chemistry; D002152:Calorimetry, Differential Scanning; D002482:Cellulose / Q000031:analogs & derivatives / Q000737:chemistry; D003460:Crystallization; D006801:Humans; D006860:Hydrogen Bonding; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D057139:Nanofibers / Q000737:chemistry*; D010949:Plasma / Q000737:chemistry; D011142:Polyvinyl Alcohol / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature; D013997:Time Factors; D023822:Tissue Engineering; D054457:Tissue Scaffolds
chemical_list: D001031:Apatites; D001672:Biocompatible Materials; D002130:Calcium Phosphates; D011142:Polyvinyl Alcohol; D002482:Cellulose; C002283:hydroxyethylcellulose; C020243:calcium phosphate
keywords: Hydroxyethyl cellulose; bone tissue engineering; bone-like apatite; electrospinning; simulated body fluid