title: Bridging the spectral gap in fluorescent proteins through directed evolution.
abstract: Fluorescent proteins are used as noninvasive tags for protein trafficking, structure, and action. In this issue of Chemistry & Biology, Hoi and colleagues present a new optimized zFP538 yellow fluorescent protein called mPapaya1 that is bright, monomeric, and an excellent fusion partner for cellular proteins.
authors.affiliation: Laboratory of Molecular Biophysics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Paul B
authors.initials: PB
authors.lastname: Whittredge
authors.forename: Justin W
authors.initials: JW
authors.lastname: Taraska
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000201:enzymology*; D008164:Luminescent Proteins / Q000737:chemistry* / Q000235:genetics*; D015202:Protein Engineering
chemical_list: D008164:Luminescent Proteins