title: Site specificity of protein glycation.
abstract: The rate of nonenzymatic glycation of a protein amino group is dependent upon a number of factors, such as the accessibility to glucose molecules in solution, and local acid-base catalysis of the rearrangement of the Schiff base that is formed initially. This is illustrated by a study of the site specificity of liver alcohol dehydrogenase, in which an attempt has been made to interpret the data in terms of the three-dimensional structure of the enzyme molecule.
authors.affiliation: Department of Biochemistry, Queen's University, K7L 3N6, Kingston, Ontario, Canada.
authors.forename: D J
authors.initials: DJ
authors.lastname: Walton
authors.forename: B H
authors.initials: BH
authors.lastname: Shilton