title: S-[2-Carboxy-1-(1H-imidazol-4-yl)ethyl]cysteine in normal human urine.
abstract: A compound, which had the same mobility on a high-voltage paper electrophoretogram and the sameR F value on a thin-layer chromatogram as those ofS-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]cysteine (I), was partially purified from human urine by ion-exchange column chromatography. The compound gave a signal at m/z 260 on its FAB mass spectrum, which was assigned as MH(+) of compound I. These results suggest that the urinary compound is compound I and it is a physiological precursor of 3-[(carboxymethyl)thio]-3-(1H-imidazol-4-yl)propanoic acid [Kinuta et al., (1991) Biochem J 275: 617-621].
authors.affiliation: Department of Biochemistry, Okayama University Medical School, 2-5-1 Shikatacho, 700, Okayama, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kinuta
authors.forename: N
authors.initials: N
authors.lastname: Masuoka
authors.forename: K
authors.initials: K
authors.lastname: Yao
authors.forename: J
authors.initials: J
authors.lastname: Ohta
authors.forename: S
authors.initials: S
authors.lastname: Yoshida
authors.forename: S
authors.initials: S
authors.lastname: Futani
authors.forename: T
authors.initials: T
authors.lastname: Ubuka