title: Synthesis and characterization of poly(1,2-propanediol-co-1,8-octanediol-co-citrate) biodegradable elastomers for tissue engineering.
abstract: In this paper, citric acid, 1,8-octanediol and 1,2-propanediol were used as reactive monomers to synthesize poly(1,2-propanediol-co-1,8-octanediol-co-citrate) (PPOC) elastomers by melt polycondensation. The PPOC elastomers were characterized by FTIR, 1H-NMR, thermal gravimetric analysis (TGA), differential scanning calorimetry (DSC), hydrophilic test and mechanical test. The results indicated that citric acid had reacted with 1,8-octanediol and 1,2-propanediol, respectively. The sol content, swelling degree and hydrophilicity of PPOC elastomers increased with the higher content of 1,2-propanediol, while the tensile strength and the thermal degradation temperature decreased. The results indicate the addition of 1,2-propanediol reduces the crosslinking density and the flexibility of PPOC elastomers.
authors.affiliation: Key Laboratory of Green Chemical Engineering and Technology of College of Heilongjiang Province, College of Chemical and Environmental Engineering, Harbin University of Science and Technology, Harbin 150040, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Zheng
authors.forename: Ping
authors.initials: P
authors.lastname: Pan
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Sun
authors.forename: Yanfei
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry*; D002152:Calorimetry, Differential Scanning; D002951:Citrates / Q000138:chemical synthesis / Q000737:chemistry*; D019343:Citric Acid / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry; D004548:Elasticity; D020724:Elastomers; D057927:Hydrophobic and Hydrophilic Interactions; D009682:Magnetic Resonance Spectroscopy; D008422:Materials Testing; D000442:Octanols / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D019946:Propylene Glycol / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature; D013718:Tensile Strength; D013818:Thermogravimetry; D023822:Tissue Engineering / Q000295:instrumentation*
chemical_list: D001672:Biocompatible Materials; D002951:Citrates; D003432:Cross-Linking Reagents; D020724:Elastomers; D000442:Octanols; D011108:Polymers; C000588970:poly(1,2-propanediol-co-1,8-octanediol-co-citrate); D019343:Citric Acid; D019946:Propylene Glycol
keywords: 1,2-propanediol; Poly(1,2-propanediol-co-1,8-octanediol-co-citrate); elastomer