title: Asymmetrical weakness associated with central nervous system involvement in a patient with guillain-barrè syndrome.
abstract: Guillain-Barrè syndrome (GBS) is usually associated with symmetrical weakness, and therefore asymmetrical weakness may confuse diagnosis. We report on a patient with GBS subsequent to Campylobacter jejuni enteritis who had asymmetrical weakness with CNS involvement. The patient tested positive for anti-ganglioside antibodies, including anti-GM1 IgM, anti-GD1b IgG, and anti-GT1a IgG. Patients with GBS can manifest asymmetrical signs and symptoms attributable to CNS involvement. Prompt, accurate diagnosis and treatment of post-C. jejuni GBS is especially important because its prognosis is relatively poor.
authors.affiliation: Department of Neurology, Nara Medical University School of Medicine, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Kiriyama
authors.forename: Makito
authors.initials: M
authors.lastname: Hirano
authors.forename: Susumu
authors.initials: S
authors.lastname: Kusunoki
authors.forename: Daiji
authors.initials: D
authors.lastname: Morita
authors.forename: Minako
authors.initials: M
authors.lastname: Hirakawa
authors.forename: Yasuyo
authors.initials: Y
authors.lastname: Tonomura
authors.forename: Takanori
authors.initials: T
authors.lastname: Kitauchi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ueno
keywords: CNS; GBS; Guillain-Barrè syndrome; asymmetrical weakness; central nervous system; symmetrical weakness