title: Synthesis of axially chiral gold complexes and their applications in asymmetric catalyses.
abstract: Several novel chiral N-heterocyclic carbene and phosphine ligands were prepared from (S)-BINOL. Moreover, their ligated Au complexes were also successfully synthesized and characterized by X-ray crystal diffraction. A weak gold-π interaction between the Au atom and the aromatic ring in these gold complexes was identified. Furthermore, we confirmed the formation of a pair of diastereomeric isomers in NHC gold complexes bearing an axially chiral binaphthyl moiety derived from the hindered rotation around C-C and C-N bonds. In the asymmetric intramolecular hydroamination reaction most of these chiral Au(I) complexes showed good catalytic activities towards olefins tethered with a NHTs functional group to give the corresponding product in moderate yields and up to 29% ee.
authors.affiliation: Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry & Molecular Engineering, East China University of Science and Technology, and 130 MeiLong Road, Shanghai 200237, People's Republic of China.
authors.forename: Yin-Wei
authors.initials: YW
authors.lastname: Sun
authors.forename: Qin
authors.initials: Q
authors.lastname: Xu
authors.forename: Min
authors.initials: M
authors.lastname: Shi
keywords: NHC gold complex; asymmetric gold catalysis; chiral Au catalysts; gold-π interaction