title: Long-lasting insecticidal nets are synergistic with mass drug administration for interruption of lymphatic filariasis transmission in Nigeria.
abstract: In central Nigeria Anopheles mosquitoes transmit malaria and lymphatic filariasis (LF). The strategy used for interrupting LF transmission in this area is annual mass drug administration (MDA) with albendazole and ivermectin, but after 8 years of MDA, entomological evaluations in sentinel villages showed continued low-grade mosquito infection rates of 0.32%. After long-lasting insecticidal net (LLIN) distribution by the national malaria program in late 2010, however, we were no longer able to detect infected vectors over a 24-month period. This is evidence that LLINs are synergistic with MDA in interrupting LF transmission.
authors.affiliation: The Carter Center, Jos, Plateau State, Nigeria.
authors.forename: Abel
authors.initials: A
authors.lastname: Eigege
authors.forename: Alphonsus
authors.initials: A
authors.lastname: Kal
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Miri
authors.forename: Adamu
authors.initials: A
authors.lastname: Sallau
authors.forename: John
authors.initials: J
authors.lastname: Umaru
authors.forename: Hayward
authors.initials: H
authors.lastname: Mafuyai
authors.forename: Yohanna S
authors.initials: YS
authors.lastname: Chuwang
authors.forename: Goshit
authors.initials: G
authors.lastname: Danjuma
authors.forename: Jacob
authors.initials: J
authors.lastname: Danboyi
authors.forename: Solomon E
authors.initials: SE
authors.lastname: Adelamo
authors.forename: Bulus S
authors.initials: BS
authors.lastname: Mancha
authors.forename: Bridget
authors.initials: B
authors.lastname: Okoeguale
authors.forename: Amy E
authors.initials: AE
authors.lastname: Patterson
authors.forename: Lindsay
authors.initials: L
authors.lastname: Rakers
authors.forename: Frank O
authors.initials: FO
authors.lastname: Richards
mesh_terms: D015766:Albendazole / Q000008:administration & dosage; D000818:Animals; D000852:Anopheles / Q000187:drug effects / Q000254:growth & development / Q000469:parasitology*; D003140:Communicable Disease Control / Q000379:methods*; D004605:Elephantiasis, Filarial / Q000188:drug therapy / Q000517:prevention & control* / Q000635:transmission*; D005369:Filaricides / Q000008:administration & dosage*; D006801:Humans; D057148:Insecticide-Treated Bednets / Q000706:statistics & numerical data*; D007306:Insecticides / Q000494:pharmacology*; D007559:Ivermectin / Q000008:administration & dosage; D009549:Nigeria / Q000453:epidemiology
chemical_list: D005369:Filaricides; D007306:Insecticides; D007559:Ivermectin; D015766:Albendazole