title: Quadriceps traumatic myositis ossificans in a football player: management with intravenous pamidronate.
abstract: Myositis ossificans (MO) can be a significant complication of traumatic muscle contusion. Bisphosphates have been used in management of heterotopic ossification after spinal cord injury, but there is a lack of evidence with respect to MO in the sporting population. We present a case of a 14-year-old male football player with posttraumatic quadriceps MO, treated with 2 doses of intravenous pamidronate. This was associated with improvement in clinical features and imaging and a reduced urinary N-terminal telopeptide, a marker of bone turnover. This case demonstrates that bisphosphonates may be a potential treatment option in MO.
authors.affiliation: Department of Rheumatology and Sport and Exercise Medicine, Royal National Orthopaedic Hospital, Stanmore, Middlesex, United Kingdom.
authors.forename: Sivanadian
authors.initials: S
authors.lastname: Mani-Babu
authors.forename: Roger
authors.initials: R
authors.lastname: Wolman
authors.forename: Richard
authors.initials: R
authors.lastname: Keen
mesh_terms: D061605:Administration, Intravenous; D000293:Adolescent; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D004164:Diphosphonates / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009221:Myositis Ossificans / Q000188:drug therapy* / Q000209:etiology; D000077268:Pamidronate; D052097:Quadriceps Muscle / Q000293:injuries*; D012916:Soccer / Q000293:injuries*; D016896:Treatment Outcome
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D000077268:Pamidronate