title: Effects of suture position on left ventricular fluid mechanics under mitral valve edge-to-edge repair.
abstract: Mitral valve (MV) edge-to-edge repair (ETER) is a surgical procedure for the correction of mitral valve regurgitation by suturing the free edge of the leaflets. The leaflets are often sutured at three different positions: central, lateral and commissural portions. To study the effects of position of suture on left ventricular (LV) fluid mechanics under mitral valve ETER, a parametric model of MV-LV system during diastole was developed. The distribution and development of vortex and atrio-ventricular pressure under different suture position were investigated. Results show that the MV sutured at central and lateral in ETER creates two vortex rings around two jets, compared with single vortex ring around one jet of the MV sutured at commissure. Smaller total orifices lead to a higher pressure difference across the atrio-ventricular leaflets in diastole. The central suture generates smaller wall shear stresses than the lateral suture, while the commissural suture generated the minimum wall shear stresses in ETER.
authors.affiliation: College of Electromechanical Engineering, Qingdao University of Science and Technology, Qingdao, China.
authors.forename: Dongxing
authors.initials: D
authors.lastname: Du
authors.forename: Song
authors.initials: S
authors.lastname: Jiang
authors.forename: Ze
authors.initials: Z
authors.lastname: Wang
authors.forename: Yingying
authors.initials: Y
authors.lastname: Hu
authors.forename: Zhaoming
authors.initials: Z
authors.lastname: He
mesh_terms: D001011:Aorta / Q000473:pathology; D013504:Cardiovascular Surgical Procedures; D003971:Diastole; D006352:Heart Ventricles / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D008943:Mitral Valve / Q000473:pathology* / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000503:physiopathology* / Q000601:surgery; D008955:Models, Cardiovascular; D011312:Pressure; D033081:Shear Strength; D013314:Stress, Mechanical; D013536:Suture Techniques; D013537:Sutures; D017725:Ventricular Pressure
keywords: Left ventricular; atrio-ventricular pressure; edge to edge repair (ETER); mitral valve; vortex; wall shear stress