title: Isolated posterior fossa involvement in posterior reversible encephalopathy syndrome.
abstract: Posterior reversible encephalopathy syndrome (PRES) is characterized by reversible vasogenic edema affecting the subcortical white matter of bilateral occipital and parietal lobes. We describe a case of isolated posterior fossa involvement of PRES which occurred during remission induction chemotherapy for T-cell acute lymphoblastic leukemia. Both the brainstem and cerebellum were extensively involved, but the supratentorial structures were completely spared. The follow-up magnetic resonance images revealed reversibility of most lesions. The knowledge of atypical radiological features of PRES is essential for prompt diagnosis.
authors.affiliation: Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital; Kita-ku, Sapporo, Japan - kktha@med.hokudai.ac.jp.
authors.forename: Yukie
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Khin Khin
authors.initials: KK
authors.lastname: Tha
authors.forename: Akihiro
authors.initials: A
authors.lastname: Iguchi
authors.forename: Yuko
authors.initials: Y
authors.lastname: Cho
authors.forename: Atsushi
authors.initials: A
authors.lastname: Yoshida
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Fujima
authors.forename: Akiko
authors.initials: A
authors.lastname: Tsukahara
authors.forename: Hiroki
authors.initials: H
authors.lastname: Shirato
authors.forename: Satoshi
authors.initials: S
authors.lastname: Terae
mesh_terms: D001933:Brain Stem / Q000473:pathology*; D002531:Cerebellum / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009413:Nerve Fibers, Myelinated / Q000473:pathology*; D054038:Posterior Leukoencephalopathy Syndrome / Q000150:complications / Q000473:pathology*; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D012074:Remission Induction
keywords: brainstem; cerebellum; posterior fossa; posterior reversible encephalopathy syndrome