title: Effect of treatment of chum salmon Oncorhynchus keta (Walbaum) eggs with 1,3;1,6-β-D-glucans on their development and susceptibility to Saprolegnia infection.
abstract: The effects of six 1,3;1,6-β-D-glucooligo- and polysaccharides with different structures (ranging from 1 to 10 kDa in molecular mass and containing 10-25% of β-1,6-linked glucose residues) from brown algae, Saccharina cichorioides, on development of the chum salmon, Oncorhynchus keta (Walbaum), were evaluated. Exposure of chum salmon eggs to 1,3;1,6-β-D-glucans with a molecular mass of more than 2 kDa increased the survival of embryos and juveniles and their resistance to Saprolegnia infection by up to 2.5-fold, leading to a weight gain in juveniles of 40-55% compared with The control chum salmons. The 1,3;1,6-β-D-glucans with molecular mass of 6-8 kDa and used at a at concentration of 0.5 mg mL(-1) rendered the best stimulative effect.
authors.affiliation: Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Academy of Sciences, Vladivostok, Russia.
authors.forename: M
authors.initials: M
authors.lastname: Kiseleva
authors.forename: L
authors.initials: L
authors.lastname: Balabanova
authors.forename: L
authors.initials: L
authors.lastname: Elyakova
authors.forename: V
authors.initials: V
authors.lastname: Rasskazov
authors.forename: T
authors.initials: T
authors.lastname: Zvyagintseva
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D060467:Disease Resistance / Q000187:drug effects*; D004625:Embryo, Nonmammalian / Q000187:drug effects; D005393:Fish Diseases / Q000517:prevention & control*; D005936:Glucans / Q000494:pharmacology*; D048788:Growth and Development / Q000187:drug effects; D017685:Oncorhynchus keta / Q000196:embryology / Q000254:growth & development / Q000276:immunology*; D010273:Parasitic Diseases, Animal / Q000517:prevention & control*; D044762:Saprolegnia / Q000502:physiology*; D015053:Zygote / Q000187:drug effects* / Q000254:growth & development / Q000469:parasitology
chemical_list: D000276:Adjuvants, Immunologic; D005936:Glucans
keywords: Oncorhynchus keta; brown algae; fish eggs; glucans; immunostimulants; polysaccharides