title: Prevalence of colorectal neoplasia among young African Americans and Hispanic Americans.
abstract: BACKGROUND
  The disproportionately higher incidence of and mortality from colorectal cancer (CRC) among African Americans (AA) led the American College of Gastroenterology to recommend screening starting at age 45 in 2005.
  
  
  OBJECTIVE
  The purpose of this study was to determine the prevalence of colorectal neoplasia among 40-49-year-old inner city AA and Hispanic Americans (HA).
  
  
  METHODS
  We reviewed the medical records of 2,435 inner city AA and HA who underwent colonoscopy regardless of indication and compared the prevalence of colorectal neoplasia between AA and HA patients. We used logistic regression models to calculate odds ratios (OR) and 95 % confidence intervals (CI).
  
  
  RESULTS
  There were 2,163 AAs and 272 HA. There were 57 % women in both groups. A total of 158 (7 %) AA and 9 (3 %) HA (P = 0.014) underwent the procedures for CRC screening. When compared to HAs, AAs had higher prevalence of any polyp (35 vs. 18 %, OR = 2.53; 95 % CI 1.82-3.52). Overall, AA had higher prevalence of colorectal neoplasia (adenoma and cancer) when compared to HAs (16 vs. 10 %; OR = 1.68; 95 % CI 1.10-2.56).
  
  
  CONCLUSIONS
  We observed a higher frequency of colorectal neoplasia among 40-49-year-old AAs as compared to HAs suggesting an increased susceptibility to CRC risk in this population.
authors.affiliation: Cancer Research Center and Department of Medicine, Department of Pathology, Howard University College of Medicine, 2041 Georgia Avenue, N.W., Washington, DC, 20060, USA, hashktorab@howard.edu.
authors.forename: Hassan
authors.initials: H
authors.lastname: Ashktorab
authors.forename: Mansour
authors.initials: M
authors.lastname: Paydar
authors.forename: Hassan Hassanzadeh
authors.initials: HH
authors.lastname: Namin
authors.forename: Andrew
authors.initials: A
authors.lastname: Sanderson
authors.forename: Rehana
authors.initials: R
authors.lastname: Begum
authors.forename: Hassan
authors.initials: H
authors.lastname: Brim
authors.forename: Heena
authors.initials: H
authors.lastname: Panchal
authors.forename: Edward
authors.initials: E
authors.lastname: Lee
authors.forename: Angesom
authors.initials: A
authors.lastname: Kibreab
authors.forename: Mehdi
authors.initials: M
authors.lastname: Nouraie
authors.forename: Adeyinka O
authors.initials: AO
authors.lastname: Laiyemo
mesh_terms: D000236:Adenoma / Q000175:diagnosis / Q000208:ethnology*; D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data*; D017677:Age Distribution; D000367:Age Factors; D016009:Chi-Square Distribution; D003111:Colonic Polyps / Q000175:diagnosis / Q000208:ethnology*; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000208:ethnology*; D005260:Female; D006630:Hispanic or Latino / Q000706:statistics & numerical data*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D012111:Residence Characteristics; D012307:Risk Factors; D014481:United States / Q000453:epidemiology; D014504:Urban Health