title: Epidemiological survey-based formulae to approximate incidence and prevalence of neurological disorders in the United States: a meta-analysis.
abstract: BACKGROUND
  This study aims to create a convenient reference for both clinicians and researchers so that vis-à-vis comparisons between brain disorders can be made quickly and accurately. We report here the incidence and prevalence of the major adult-onset brain disorders in the United States using a meta-analysis approach.
  
  
  METHODS
  Epidemiological figures were collected from the most recent, reliable data available in the research literature. Population statistics were based on the most recent census from the US Census Bureau. Extrapolations were made only when necessary. The most current epidemiological studies for each disorder were chosen. All effort was made to use studies based on national cohorts. Studies reviewed were conducted between 1950 and 2009. The data of the leading studies for several neurological studies was compiled in order to obtain the most accurate extrapolations. Results were compared to commonly accepted values in order to evaluate validity.
  
  
  RESULTS
  It was found that 6.75% of the American adult population is afflicted with brain disorders. This number was eclipsed by the 8.02% of Floridians with brain disorders, which is due to the large aged population residing in the state.
  
  
  CONCLUSIONS
  There was a noticeable lack of epidemiological data concerning adult-onset brain disorders. Since approximately 1 out of every 7 households is affected by brain disorders, increased research into this arena is warranted.
authors.affiliation: Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida, United States of America.
authors.forename: Cesar V
authors.initials: CV
authors.lastname: Borlongan
authors.forename: Jack
authors.initials: J
authors.lastname: Burns
authors.forename: Naoki
authors.initials: N
authors.lastname: Tajiri
authors.forename: Christine E
authors.initials: CE
authors.lastname: Stahl
authors.forename: Nathan L
authors.initials: NL
authors.lastname: Weinbren
authors.forename: Hideki
authors.initials: H
authors.lastname: Shojo
authors.forename: Paul R
authors.initials: PR
authors.lastname: Sanberg
authors.forename: Dwaine F
authors.initials: DF
authors.lastname: Emerich
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kaneko
authors.forename: Harry R
authors.initials: HR
authors.lastname: van Loveren
mesh_terms: D001927:Brain Diseases / Q000453:epidemiology; D003625:Data Collection; D006801:Humans; D015994:Incidence; D009422:Nervous System Diseases / Q000453:epidemiology*; D015995:Prevalence; D014481:United States