title: [News in the treatment of Dupuytren's disease: from surgery to collagenase's injection].
abstract: Dupuytren's disease is a benign fibromatosis affecting the palmar and digital fascia and causing flexion contracture of the affected fingers. Up to date, this affection has no curative treatment available. The author is presenting an updated review of the therapeutic arsenal available for Dupuytren's disease cords correction. Open fasciectomy remains the "gold standard" surgical treatment of the disease but enzymatic treatment of the cords by injected collagenase clostridium histolyticum represents a promising new therapeutic. Recent published data are showing that this procedure gives comparable results to the published ones for segmental fasciectomy in terms of cords correction and recurrence prevention but with the advantage of a quicker recovery with a minimal morbidity.
authors.affiliation: Service de Chirurgie plastique, Hopital Erasme, Bruxelles. nicolas.cuylits@erasme.ulb.ac.be
authors.forename: N
authors.initials: N
authors.lastname: Cuylits
mesh_terms: D017364:Collagenases / Q000008:administration & dosage*; D004387:Dupuytren Contracture / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D006225:Hand / Q000601:surgery; D006801:Humans; D015552:Injections, Intralesional; D013514:Surgical Procedures, Operative
chemical_list: D017364:Collagenases