title: Usefulness of nasal packing with silver-containing carboxy methylated cellulose in endonasal sinus surgery.
abstract: OBJECTIVE
  Silver-containing carboxymethylcellulose fiber dressing (Aquacel®-Ag) has been used to treat burns and ulcers with a large amount of exudate. The aim of this investigation was to confirm whether Aquacel®-Ag has beneficial effects when it is used as nasal packing.
  
  
  METHODS
  We included 44 patients who underwent bilateral endoscopic sinus surgery due to chronic rhino-sinusitis. Beschitin-F® or Aquacel®-Ag was packed postoperatively into the bilateral middle meatus. Patient's comfort was recorded using a VAS, as well as wound healing, postoperative bleeding and local infection. Postoperative-specific organisms were also evaluated from the removed packing materials located in the middle meatus when they were removed on the 4th day after surgery.
  
  
  RESULTS
  The scores for nasal obstruction and pain were not statistically different in each group. Postoperative bacteriologic studies indicated marked differences. Coagulase-negative staphylococci were predominant and potential pathogens were recovered in a few cases in the Aquacel®-Ag group. In contrast, potential pathogens, including Streptococcus pneumonia, Haemophilus influenza, and Gram-negative rods, were predominant in the Beschitin-F® group.
  
  
  CONCLUSIONS
  The results indicate that Aquacel®-Ag might contribute to hemostasis, wound healing, and patient comfort after endonasal surgery, similar to Beschitin-F®. Additionally, it may have advantages concerning the prevention of postoperative infection.
authors.affiliation: Department of Otolaryngology, Mitoyo General Hospital, Mitoyo-shi, Toyohama-cho, Himehama 708, Kagawa 769-1695, Japan; Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan. Electronic address: kakaka@med.kagawa-u.ac.jp.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Akiyama
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Karaki
authors.affiliation: Department of Otolaryngology, Mitoyo General Hospital, Mitoyo-shi, Toyohama-cho, Himehama 708, Kagawa 769-1695, Japan.
authors.forename: Masafumi
authors.initials: M
authors.lastname: Yonezaki
authors.affiliation: Department of Otolaryngology, Mitoyo General Hospital, Mitoyo-shi, Toyohama-cho, Himehama 708, Kagawa 769-1695, Japan.
authors.forename: Rieko
authors.initials: R
authors.lastname: Goto
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan.
authors.forename: Rhyuhei
authors.initials: R
authors.lastname: Inamoto
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hoshikawa
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan.
authors.forename: Nozomu
authors.initials: N
authors.lastname: Mori
mesh_terms: D000328:Adult; D001458:Bandages; D002266:Carboxymethylcellulose Sodium / Q000627:therapeutic use*; D002908:Chronic Disease; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000517:prevention & control; D010256:Paranasal Sinuses / Q000601:surgery*; D011182:Postoperative Care / Q000379:methods*; D019106:Postoperative Hemorrhage / Q000517:prevention & control*; D012220:Rhinitis / Q000601:surgery*; D018030:Silver Compounds / Q000627:therapeutic use*; D016037:Single-Blind Method; D012852:Sinusitis / Q000601:surgery*; D013530:Surgical Wound Infection / Q000517:prevention & control*; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D018030:Silver Compounds; D002266:Carboxymethylcellulose Sodium
keywords: Aquacel(®)-Ag; Beschitin; Endoscopic sinus surgery; Nasal packing; Silver-containing carboxy methylated cellulose