title: Xylanthraquinone, a new anthraquinone from the fungus Xylaria sp. 2508 from the South China Sea.
abstract: Xylanthraquinone (1), a new anthraquinone, along with three known compounds, altersolanol A (2), deoxybostrycin (3) and bostrycin (4) was isolated from the fungus Xylaria sp. 2508 from the South China Sea. The structures of these compounds were identified by NMR experiments, and the absolute configuration of compound 1 was further confirmed by single-crystal X-ray diffraction with Cu Kα radiation. Compounds 1-4 did not show inhibitory activities against Mycobacterium tuberculosis protein tyrosine phosphatase B (IC50 values more than 100 μM).
authors.affiliation: a School of Chemistry and Chemical Engineering, Sun Yat-sen University , Guangzhou 510275 , P.R. China.
authors.forename: Xishan
authors.initials: X
authors.lastname: Huang
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Sun
authors.forename: Shao'e
authors.initials: S
authors.lastname: Lin
authors.forename: Ze'en
authors.initials: Z
authors.lastname: Xiao
authors.forename: Hanxiang
authors.initials: H
authors.lastname: Li
authors.forename: Ding
authors.initials: D
authors.lastname: Bo
authors.forename: Zhigang
authors.initials: Z
authors.lastname: She
mesh_terms: D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002681:China; D018360:Crystallography, X-Ray; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D009792:Oceans and Seas; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1 / Q000187:drug effects; D013098:Xylariales / Q000737:chemistry*
chemical_list: D000880:Anthraquinones; C000590811:xylanthraquinone; C042834:9,10-anthraquinone; C034287:bostrycin; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1