title: First description of bla(NDM-1), bla(OXA-48), bla(OXA-181) producing Enterobacteriaceae strains in Romania.
abstract: We report the first isolation and characterization of several Enterobacteriaceae strains harboring bla(NDM-1), bla(OXA-48) and/or bla(OXA-181) genes in a Romanian emergency teaching hospital. Between January 2010 and September 2012 nine carbapenemase-producing Enterobacteriaceae strains were identified. The bla(NDM-1) gene was present in two Enterobacter cloacae strains, an Escherichia coli and two Klebsiella pneumoniae strains. One of these K. pneumoniae strains also harbored the bla(OXA-181) gene. Three other K. pneumoniae strains and one Serratia marcescens carried bla(OXA-48).
authors.affiliation: University of Medicine and Pharmacy, Targu Mures, Romania; Mures County Clinical Emergency Hospital, Targu Mures, Romania. Electronic address: szekely.edit@yahoo.com.
authors.forename: Edit
authors.initials: E
authors.lastname: Székely
authors.forename: Ivelina
authors.initials: I
authors.lastname: Damjanova
authors.forename: Laura
authors.initials: L
authors.lastname: Jánvári
authors.forename: Krisztina E
authors.initials: KE
authors.lastname: Vas
authors.forename: Szabolcs
authors.initials: S
authors.lastname: Molnár
authors.forename: Doina V
authors.initials: DV
authors.lastname: Bilca
authors.forename: Lilla K
authors.initials: LK
authors.lastname: Lőrinczi
authors.forename: Akos
authors.initials: A
authors.lastname: Tóth
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000382:microbiology*; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012383:Romania; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism*; D047090:beta-Lactams / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D047090:beta-Lactams; D001618:beta-Lactamases
keywords: Antimicrobial resistance; Carbapenemases; Molecular characterization; NDM-1; OXA-48