title: HDAC5--a critical player in the p53 acetylation network.
abstract: In this issue of Molecular Cell, Sen et al. (2013) identify HDAC5 as a deacetylase with specificity for the K120 site of p53, a key residue of p53 that undergoes acetylation after DNA damage and regulates target gene selection.
authors.affiliation: Department of Biology, York University, Toronto M3J 1P3, Ontario, Canada.
authors.forename: Sam Sulgi
authors.initials: SS
authors.lastname: Kim
authors.forename: Samuel
authors.initials: S
authors.lastname: Benchimol
mesh_terms: D000107:Acetylation / Q000187:drug effects*; D000818:Animals; D017209:Apoptosis / Q000235:genetics*; D004249:DNA Damage / Q000235:genetics*; D006655:Histone Deacetylases / Q000235:genetics*; D006801:Humans; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*
chemical_list: D016159:Tumor Suppressor Protein p53; C404500:HDAC5 protein, human; D006655:Histone Deacetylases