title: Misdiagnosing recurrent medulloblastoma: the danger of examination and imaging without histological confirmation.
abstract: The screening and detection of recurrent medulloblastoma presents the clinician with significant diagnostic challenges, including the risk of misdiagnosis. The authors present the case of a young girl with a history of a treated standard-risk medulloblastoma that highlights the risk of assuming recurrence has occurred when clinical and/or imaging changes are observed. This girl developed both new clinical deficits and had radiographic evidence of recurrence. She subsequently experienced a complete resolution of symptoms and radiographic findings with steroids alone.
authors.affiliation: Divisions of Pediatric Hematology/Oncology.
authors.forename: Lauren
authors.initials: L
authors.lastname: Weintraub
authors.forename: Todd
authors.initials: T
authors.lastname: Miller
authors.forename: Ilana
authors.initials: I
authors.lastname: Friedman
authors.forename: Rick
authors.initials: R
authors.lastname: Abbott
authors.forename: Adam S
authors.initials: AS
authors.lastname: Levy
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002528:Cerebellar Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D002648:Child; D003907:Dexamethasone / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005221:Fatigue / Q000209:etiology; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008527:Medulloblastoma / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D010166:Palliative Care / Q000379:methods; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D016312:Treatment Refusal; D014786:Vision Disorders / Q000209:etiology; D014839:Vomiting / Q000209:etiology
chemical_list: D000970:Antineoplastic Agents; D003907:Dexamethasone