title: Does metabolic syndrome or its components differ in naturally and surgically menopausal women?
abstract: OBJECTIVE
  This study aimed to compare metabolic syndrome and its components in naturally and surgically menopausal women.
  
  
  METHODS
  This is a longitudinal study, with incident case and control groups, conducted on 446 women participants of the Tehran Lipid and Glucose Study, who experienced surgical or natural menopause over a 10-year period. In both groups, data collection was conducted using questionnaires including information on demographic, reproductive and metabolic characteristics at baseline and again after 3 years. Physical examinations and the biochemical profiles were also assessed.
  
  
  RESULTS
  During the follow-up, metabolic syndrome was observed in 28.7% and 32.5% of the naturally menopause and surgically menopausal women, respectively. Mean fasting blood sugar and 2-h plasma glucose were significantly higher in the surgically menopause group, compared to the naturally menopause one, whereas mean systolic blood pressure was significantly higher in naturally menopausal women as compared to surgically menopause ones, after further adjustment for premenopausal status.
  
  
  CONCLUSIONS
  Although no difference in the prevalence of metabolic syndrome in naturally menopausal women and in surgically menopausal women was found, the components of metabolic syndrome were more prevalent among those with surgical menopause.
authors.affiliation: Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences.
authors.forename: M
authors.initials: M
authors.lastname: Farahmand
authors.forename: F
authors.initials: F
authors.lastname: Ramezani Tehrani
authors.forename: M
authors.initials: M
authors.lastname: Simbar
authors.forename: Y
authors.initials: Y
authors.lastname: Mehrabi
authors.forename: D
authors.initials: D
authors.lastname: Khalili
authors.forename: F
authors.initials: F
authors.lastname: Azizi
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D005260:Female; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008055:Lipids / Q000097:blood; D008137:Longitudinal Studies; D008593:Menopause / Q000378:metabolism*; D008594:Menopause, Premature / Q000378:metabolism*; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism; D008875:Middle Aged; D010052:Ovariectomy / Q000009:adverse effects*; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism; D015995:Prevalence; D012959:Socioeconomic Factors; D016387:Women's Health
chemical_list: D001786:Blood Glucose; D008055:Lipids
keywords: BLOOD PRESSURE; BLOOD SUGAR; METABOLIC SYNDROME; NATURAL MENOPAUSE; SERUM LIPOPROTEINS; SURGICAL MENOPAUSE