title: Anuria in a solitary kidney with Candida bezoars managed conservatively.
abstract: Renal involvement is regularly encountered in neonates with invasive candidiasis, especially when risk factors like congenital malformations of the renal tract or poor bladder emptying and preterm birth are present. However, complete obstruction of the renal collecting system by fungal balls is rare. Although conservative management has been advocated for partial obstruction, complete obstruction is considered an indication for surgical drainage. We report a patient with anuria and Candida albicans bezoars in a solitary kidney, suggesting post-renal acute kidney injury. The patient was treated with systemic fluconazole and peritoneal dialysis for 4 days. The fungus balls disappeared and renal function recovered.
  
  
  CONCLUSIONS
  Systemic antifungal therapy leads to clearance of obstructing fungus balls, and nephrostomy should be reserved for anuria due to bilateral complete obstruction with severe hydronephrosis. In these cases, temporary dialysis is a potential alternative.
authors.affiliation: Department of Pediatrics, VU University Medical Centre, PO box 7057, 1007 MB, Amsterdam, The Netherlands, jaapschilperoort@hotmail.com.
authors.forename: Jaap V
authors.initials: JV
authors.lastname: Schilperoort
authors.forename: Liesbeth L
authors.initials: LL
authors.lastname: de Wall
authors.forename: Henricus J R
authors.initials: HJ
authors.lastname: van der Horst
authors.forename: Joanna A E
authors.initials: JA
authors.lastname: van Wijk
authors.forename: Jonathan I M L
authors.initials: JI
authors.lastname: Verbeke
authors.forename: Arend
authors.initials: A
authors.lastname: Bokenkamp
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D001002:Anuria / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D001630:Bezoars / Q000150:complications* / Q000000981:diagnostic imaging / Q000382:microbiology; D002176:Candida albicans / Q000302:isolation & purification*; D002177:Candidiasis / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D003937:Diagnosis, Differential; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000382:microbiology; D008297:Male; D006435:Renal Dialysis / Q000379:methods*; D014463:Ultrasonography
chemical_list: D000935:Antifungal Agents