title: Biological activity of alpha-alkyl-amino acids.
abstract: A series of alpha-alkyl-amino acids were tested for some biological functions in the mouse (OF-1 Himberg) by adding them to the animal chow (30 mg/kg/day) for a period of six weeks. No differences in fluid or food uptake could be observed during the feeding period, as compared to a control group. Histology of liver and kidney did not show any changes. Testing routine clinical chemical parameters (serum substrates and enzymes) revealed the following changes: Hex-Ala and But-Abu increased the serum glucose levels. But-Abu dramatically lowered the triglycerides. Serum albumin was increased by Pent-Ala, Me-Val, and But-Abu. LDH was inhibited by But-Abu.
authors.affiliation: Department of Pediatrics, University of Vienna, Währinger Gürtel 18-20, A-1090, Vienna, Austria.
authors.forename: B
authors.initials: B
authors.lastname: Lubec
authors.forename: K R
authors.initials: KR
authors.lastname: Herkner
authors.forename: H
authors.initials: H
authors.lastname: Brückner
authors.forename: H
authors.initials: H
authors.lastname: Höger
authors.forename: J
authors.initials: J
authors.lastname: Gialamas
authors.forename: D
authors.initials: D
authors.lastname: Adamiker
authors.forename: G
authors.initials: G
authors.lastname: Lubec