title: Validation of the European Organization for Research and Treatment of Cancer cervical cancer module for Chinese patients with cervical cancer.
abstract: OBJECTIVE
  The aim of our study was to assess, for the first time, the validity, reliability, and acceptability of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life questionnaire (QLQ) cervical cancer module (CX24) in Chinese cervical cancer patients.
  
  
  METHODS
  One hundred fifteen outpatients with cervical cancer in the First Affiliated Hospital of Xinxiang Medical University from May 2013 to July 2013 were included in this study. All participants self-administered the EORTC QLQ-CX24 and the core questionnaire (EORTC QLQ-C30), and the Karnofsky Performance Scale was performed to evaluate scores. Data were analyzed with Cronbach's α coefficient, Pearson correlation test, multitrait scaling analysis, and Mann-Whitney U test.
  
  
  RESULTS
  Scale reliability was confirmed by Cronbach's α coefficients for internal consistency, which ranged from 0.71 to 0.82. Convergent and discriminant validity were confirmed by multitrait scaling analysis, which revealed three (3.4%) scaling errors for symptom experience scales and zero (0%) for body image as well as sexual/vaginal functioning scales. Higher missing value rate occurred in sexuality-related items. The clinical validity of the Chinese version of the EORTC QLQ-CX24 was demonstrated by the ability to discriminate among patients in different International Federation of Gynecology and Obstetrics stages.
  
  
  CONCLUSIONS
  The EORTC QLQ-CX24 was proved to be a reliable and valid instrument with which to measure the quality of life in cervical cancer patients in the People's Republic of China.
authors.affiliation: Department of Gynecology and Obstetrics, First Affiliated Hospital of Xinxiang Medical University, Weihui City, Henan Province, People's Republic of China.
authors.forename: Cai-Hong
authors.initials: CH
authors.lastname: Hua
authors.forename: Hui-Min
authors.initials: HM
authors.lastname: Guo
authors.forename: Xin-Lei
authors.initials: XL
authors.lastname: Guan
authors.forename: Fan-Jing
authors.initials: FJ
authors.lastname: Kong
authors.forename: Rui-Jie
authors.initials: RJ
authors.lastname: Hou
authors.forename: Xue-Ying
authors.initials: XY
authors.lastname: Zhang
authors.forename: Shao-Ru
authors.initials: SR
authors.lastname: Li
keywords: EORTC QLQ-CX24; People’s Republic of China; cervical cancer; quality of life