title: Clinical evaluation of chlorine dioxide for disinfection of dental instruments.
abstract: This study aimed to clinically evaluate the disinfection efficacy of chlorine dioxide (ClO2) for used dental instruments. An imprint culture technique demonstrated that ultrasonic cleaning of intraorally applied dental mirrors in 0.02% ClO2 for 10 minutes resulted in compete removal of microorganisms for 10 subjects. Hepatitis C virus (HCV) RNA was detected by real-time polymerase chain reaction on periodontal curettes after subgingival scaling in four HCV-infected patients and was completely removed by the same treatment procedure. Therefore, the combination of ultrasonic cleaning with ClO2 may provide an alternative to toxic disinfectants, such as glutaraldehyde and sodium hypochlorite, for disinfecting dental instruments.
authors.forename: Takao
authors.initials: T
authors.lastname: Watamoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Egusa
authors.forename: Takashi
authors.initials: T
authors.lastname: Sawase
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Yatani
mesh_terms: D000328:Adult; D000368:Aged; D018441:Biofilms / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D017606:Chlorine Compounds / Q000627:therapeutic use*; D019551:Dental Disinfectants / Q000627:therapeutic use*; D003762:Dental Instruments / Q000382:microbiology / Q000821:virology; D004203:Disinfection / Q000379:methods; D004866:Equipment Contamination / Q000517:prevention & control; D005260:Female; D005976:Glutaral / Q000627:therapeutic use; D016174:Hepacivirus / Q000187:drug effects; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D019552:Infection Control, Dental / Q000379:methods; D008297:Male; D008875:Middle Aged; D010087:Oxides / Q000627:therapeutic use*; D012973:Sodium Hypochlorite / Q000627:therapeutic use; D013357:Subgingival Curettage / Q000295:instrumentation; D014465:Ultrasonics; D055815:Young Adult
chemical_list: D017606:Chlorine Compounds; D019551:Dental Disinfectants; D010087:Oxides; C025109:chlorine dioxide; D012973:Sodium Hypochlorite; D005976:Glutaral