title: Field effect biosensing platform based on 2D α-MoO(3).
abstract: Electrical-based biosensing platforms offer ease of fabrication and simple sensing solutions. Recently, two-dimensional (2D) semiconductors have been proven to be excellent for the fabrication of field effect transistors (FETs) due to their large transconductance, which can be efficiently used for developing sensitive bioplatforms. We present a 2D molybdenum trioxide (MoO3) FET based biosensing platform, using bovine serum albumin as a model protein. The conduction channel is a nanostructured film made of 2D α-MoO3 nanoflakes, with the majority of nanoflake thicknesses being equal to or less than 2.8 nm. The response time is impressively low (less than 10 s), which is due to the high permittivity of the 2D α-MoO3 nanoflakes. The system offers a competitive solution for future biosensing applications.
authors.affiliation: School of Electrical and Computer Engineering, RMIT University , Melbourne, Victoria, Australia.
authors.forename: Sivacarendran
authors.initials: S
authors.lastname: Balendhran
authors.forename: Sumeet
authors.initials: S
authors.lastname: Walia
authors.forename: Manal
authors.initials: M
authors.lastname: Alsaif
authors.forename: Emily P
authors.initials: EP
authors.lastname: Nguyen
authors.forename: Jian Zhen
authors.initials: JZ
authors.lastname: Ou
authors.forename: Serge
authors.initials: S
authors.lastname: Zhuiykov
authors.forename: Sharath
authors.initials: S
authors.lastname: Sriram
authors.forename: Madhu
authors.initials: M
authors.lastname: Bhaskaran
authors.forename: Kourosh
authors.initials: K
authors.lastname: Kalantar-Zadeh
mesh_terms: D000818:Animals; D015374:Biosensing Techniques; D002417:Cattle; D008422:Materials Testing; D018625:Microscopy, Atomic Force; D046529:Microscopy, Electron, Transmission; D008982:Molybdenum / Q000737:chemistry*; D049329:Nanostructures; D010087:Oxides / Q000737:chemistry*; D012666:Semiconductors; D012710:Serum Albumin, Bovine / Q000737:chemistry; D013059:Spectrum Analysis, Raman; D013499:Surface Properties; D014173:Transistors, Electronic
chemical_list: D010087:Oxides; C082290:molybdenum trioxide; D012710:Serum Albumin, Bovine; D008982:Molybdenum