title: Isolated abducens nerve palsy with hyperhomocysteinemia: association and outcomes.
abstract: Ischemic abducens nerve palsy usually presents as isolated cranial nerve palsy in the middle aged and elderly patients with known risk factors such as diabetes mellitus, hypertension, dyslipidemia, carotid artery disease, etc., In this report, we describe four patients with isolated abducens nerve palsy who presented with an acute onset diplopia whose detailed history and examination were suggestive of an ischemic etiology. Detailed systemic and laboratory evaluation revealed hyperhomocysteinemia as the only potential risk factor. To the best of our knowledge this is the first report of association of hyperhomocysteinemia and isolated abducens nerve palsy.
authors.affiliation: Department of Pediatric Ophthalmology, Strabismus and Neuro-ophthalmology, L V Prasad Eye Institute, GMRV Campus, Visakhapatnam, India.
authors.forename: Virender
authors.initials: V
authors.lastname: Sachdeva
authors.forename: Vaibhev
authors.initials: V
authors.lastname: Mittal
authors.forename: Avinash
authors.initials: A
authors.lastname: Pathengay
authors.forename: Ramesh
authors.initials: R
authors.lastname: Kekunnaya
authors.forename: Amit
authors.initials: A
authors.lastname: Gupta
authors.forename: Bhoompally V
authors.initials: BV
authors.lastname: Rao
mesh_terms: D020434:Abducens Nerve Diseases / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D000293:Adolescent; D000328:Adult; D002648:Child; D003937:Diagnosis, Differential; D004172:Diplopia / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D005133:Eye Movements / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006710:Homocysteine / Q000097:blood; D006801:Humans; D020138:Hyperhomocysteinemia / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult
chemical_list: D006710:Homocysteine