title: Association between cognitive performance, physical fitness, and physical activity level in women with chronic fatigue syndrome.
abstract: Limited scientific evidence suggests that physical activity is directly related to cognitive performance in patients with chronic fatigue syndrome (CFS). To date, no other study has examined the direct relationship between cognitive performance and physical fitness in these patients. This study examined whether cognitive performance and physical fitness are associated in female patients with CFS and investigated the association between cognitive performance and physical activity level (PAL) in the same study sample. We hypothesized that patients who performed better on cognitive tasks would show increased PALs and better performance on physical tests. The study included 31 women with CFS and 13 healthy inactive women. Participants first completed three cognitive tests. Afterward, they undertook a test to determine their maximal handgrip strength, performed a bicycle ergometer test, and were provided with an activity monitor. In patients with CFS, lower peak oxygen uptake and peak heart rate were associated with slower psychomotor speed (p < 0.05). Maximal handgrip strength was correlated with working memory performance (p < 0.05). Both choice and simple reaction time were lower in patients with CFS relative to healthy controls (p < 0.05 and p < 0.001, respectively). In conclusion, physical fitness, but not PAL, is associated with cognitive performance in female patients with CFS.
authors.affiliation: Pain in Motion Research Group (PIM), Department of Human Physiology, Vrije Universiteit Brussel, Brussels, Belgium.
authors.forename: Kelly
authors.initials: K
authors.lastname: Ickmans
authors.forename: Peter
authors.initials: P
authors.lastname: Clarys
authors.forename: Jo
authors.initials: J
authors.lastname: Nijs
authors.forename: Mira
authors.initials: M
authors.lastname: Meeus
authors.forename: Dirk
authors.initials: D
authors.lastname: Aerenhouts
authors.forename: Evert
authors.initials: E
authors.lastname: Zinzen
authors.forename: Senne
authors.initials: S
authors.lastname: Aelbrecht
authors.forename: Geert
authors.initials: G
authors.lastname: Meersdom
authors.forename: Luc
authors.initials: L
authors.lastname: Lambrecht
authors.forename: Nathalie
authors.initials: N
authors.lastname: Pattyn
mesh_terms: D056044:Actigraphy; D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D005080:Exercise Test; D015673:Fatigue Syndrome, Chronic / Q000503:physiopathology*; D005260:Female; D018737:Hand Strength; D006339:Heart Rate; D006801:Humans; D008568:Memory / Q000502:physiology*; D009043:Motor Activity / Q000502:physiology*; D010101:Oxygen Consumption; D010809:Physical Fitness / Q000502:physiology*; D011446:Prospective Studies; D011930:Reaction Time / Q000502:physiology*; D013647:Task Performance and Analysis; D055815:Young Adult