title: Assessment of peripapillary retinal nerve fiber layer thickness using scanning laser polarimetry (GDx VCC) in normal Indian children.
abstract: OBJECTIVE
  To obtain reference values of RNFL thickness in normal Indian children and to study the association of RNFL thickness with central corneal thickness(CCT) and axial length(AL).
  
  
  METHODS
  200 normal Indian children (mean age 8.6 ± 2.9 yrs) were examined on the GDxVCC. The inferior average (IA), superior average (SA), temporal-superior-nasal-inferior-temporal (TSNIT) average and nerve fiber index (NFI) values were recorded and compared between males and females as well as between the different age groups. The association of TSNIT average with AL and CCT was examined.
  
  
  RESULTS
  Values for the RNFL parameters were-SA: 64.9 ± 9.7, IA: 63.8 ± 8.8, TSNIT average: 53.5 ± 7.7 and NFI 21.5 ± 10.8. Superior, inferior and TSNIT averages did not differ significantly between males and females (P = 0.25, P = 0.19, P = 0.06 respectively; Mann-Whitney U test). No significant differences were found in TSNIT average across age groups. There was a statistically significant positive correlation between CCT and TSNIT average (r = 0.25, r 2 = 0.06, P < 0.001). The correlation TSNIT average and AL(r = -0.12; r2 = 0.01) was not significant (P = 0.2).
  
  
  CONCLUSIONS
  Reference values for RNFL parameters reported for Indian children are similar those reported in adults. There is a small correlation between central corneal thickness and RNFL as reflected in average TSNIT.
authors.affiliation: Iladevi Catarct and IOL Research Centre, Ahmedabad, Gujarat, India.
authors.forename: Mayuri B
authors.initials: MB
authors.lastname: Khamar
authors.forename: Vaishali
authors.initials: V
authors.lastname: Vasavada
authors.forename: Sajani K
authors.initials: SK
authors.lastname: Shah
authors.forename: Rupal H
authors.initials: RH
authors.lastname: Trivedi
authors.forename: Ravi
authors.initials: R
authors.lastname: Thomas
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000166:cytology; D005260:Female; D005901:Glaucoma / Q000175:diagnosis; D006801:Humans; D007194:India; D008297:Male; D009412:Nerve Fibers; D009898:Optic Disk / Q000166:cytology*; D011446:Prospective Studies; D012016:Reference Values; D015203:Reproducibility of Results; D012165:Retinal Ganglion Cells / Q000166:cytology*; D057109:Scanning Laser Polarimetry / Q000379:methods*