title: On the role of NMDA receptors in blood pressure regulation in spontaneously hypertensive rats (SHR).
abstract: In the present study the binding of [(3)H]MK-801 to glutamatergic receptors of the NMDA type was compared in spontaneously hypertensive (SHR) and normotensive (WKY) rats in various brain structures (including nucleus tractus solitarii) by quantitative receptor autoradiography. Additionally, blood pressure changes after treatment with the NMDA antagonist MK-801 were studied in both strains. There were no differences between SHR and WKY rats either in the level of [(3)H]MK-801 binding or in the hypertensive reaction to MK-801.
authors.affiliation: Department of Neurophysiology, Nencki Institute, Warsaw, Poland.
authors.forename: S
authors.initials: S
authors.lastname: Glazewski
authors.forename: M
authors.initials: M
authors.lastname: Remiszewska
authors.forename: M
authors.initials: M
authors.lastname: Wutkiewicz
authors.forename: Z
authors.initials: Z
authors.lastname: Jastrzebski
authors.forename: W
authors.initials: W
authors.lastname: Danysz