title: Severe hypoalphalipoproteinaemia in a child with acute post-streptococcal glomerulonephritis (APSGN).
abstract: We describe a child with acute post-streptococcal glomerulonephritis (APSGN), who developed a very low plasma high-density lipoprotein cholesterol (α-lipoprotein) in association with transient but massive proteinuria. The hypoalphalipoproteinaemia resolved spontaneously concomitant with the remission in proteinuria and the patient had a complete clinical recovery. Urinary loss of apolipoprotein A1 may have contributed to the hypoalphalipoproteinaemia. To our knowledge, this has not been reported previously in APSGN.
authors.affiliation: Department of Pediatrics, American University of Beirut, Beirut, Lebanon.
authors.forename: Mohammad B
authors.initials: MB
authors.lastname: Alayli
authors.forename: Sami A
authors.initials: SA
authors.lastname: Sanjad
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002675:Child, Preschool; D008076:Cholesterol, HDL / Q000378:metabolism* / Q000652:urine; D005500:Follow-Up Studies; D005921:Glomerulonephritis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008297:Male; D011507:Proteinuria / Q000209:etiology / Q000503:physiopathology; D035583:Rare Diseases; D018570:Risk Assessment; D012720:Severity of Illness Index; D013290:Streptococcal Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D008076:Cholesterol, HDL