title: Fine needle aspiration cytology in the diagnosis of perioral adverse reactions to cosmetic dermal fillers.
abstract: Facial cosmetic procedures are increasingly requested, and dermal filler materials have been widely used as a nonsurgical option since the 1980s. However, injectable fillers have been implicated in local adverse reactions. Therefore, the aim of this article was to describe the use of fine needle aspiration cytology (FNAC) in the diagnosis of foreign-body reactions to the perioral injection of dermal fillers. A 69-year-old woman presented with a painful nodule on her right nasolabial fold. Intraoral FNAC was performed, and cytologic smears were examined under optical and polarized light microscopy, showing birefringent microspheres, confirming the diagnosis of an adverse reaction caused by polymethyl methacrylate filler. FNAC is a less invasive method to confirm the diagnosis of adverse reactions caused by perioral cosmetic dermal fillers.
authors.affiliation: Oral Diagnosis Department, Semiology and Oral Pathology Areas, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
authors.forename: Karina Morais
authors.initials: KM
authors.lastname: Faria
authors.affiliation: Oral Diagnosis Department, Semiology and Oral Pathology Areas, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
authors.forename: Felipe Paiva
authors.initials: FP
authors.lastname: Fonseca
authors.affiliation: Oral Diagnosis Department, Semiology and Oral Pathology Areas, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
authors.forename: Wagner Gomes
authors.initials: WG
authors.lastname: Silva
authors.affiliation: Oral Diagnosis Department, Semiology and Oral Pathology Areas, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
authors.forename: Rodrigo Neves
authors.initials: RN
authors.lastname: Silva
authors.affiliation: Oral Diagnosis Department, Semiology and Oral Pathology Areas, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
authors.forename: Pablo Agustin
authors.initials: PA
authors.lastname: Vargas
authors.affiliation: Oral Diagnosis Department, Semiology and Oral Pathology Areas, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
authors.forename: Oslei Paes
authors.initials: OP
authors.lastname: de Almeida
authors.affiliation: Oral Diagnosis Department, Semiology and Oral Pathology Areas, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
authors.forename: Marcio Ajudarte
authors.initials: MA
authors.lastname: Lopes
authors.affiliation: Oral Diagnosis Department, Semiology and Oral Pathology Areas, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil. Electronic address: alanroger@fop.unicamp.br.
authors.forename: Alan Roger
authors.initials: AR
authors.lastname: Santos-Silva
mesh_terms: D000368:Aged; D001672:Biocompatible Materials / Q000009:adverse effects*; D044963:Biopsy, Fine-Needle; D003094:Collagen / Q000009:adverse effects*; D003357:Cosmetic Techniques / Q000009:adverse effects*; D005145:Face; D005260:Female; D005549:Foreign-Body Reaction / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D011108:Polymers / Q000009:adverse effects*
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D003094:Collagen