title: Scientific principles of regenerative medicine and their application in the female reproductive system.
abstract: The goal of regenerative medicine is to repair, replace, or regenerate diseased tissues/organs in order to restore normal function. In this paper we will first discuss the general principle of regenerative medicine and the various techniques and approaches that have been used to replace or regenerate cells in diseased tissues and organs. Then, we will review different regenerative medicine approaches that have been used to treat specific diseased tissues and organs of the reproductive system in both animal and human experiments. It is clear from this article that regenerative medicine holds significant promise, and we hope that the review will serve as a platform for further development of regenerative medicine technologies for the treatment of inadequacies of the reproductive system.
authors.affiliation: Section of Reproductive Endocrinology, Department of Obstetrics & Gynecology, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States.
authors.forename: Tamer M
authors.initials: TM
authors.lastname: Yalcinkaya
authors.affiliation: Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States.
authors.forename: Sivanandane
authors.initials: S
authors.lastname: Sittadjody
authors.affiliation: Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States; Virginia Tech-Wake Forest University School of Biomedical Engineering & Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States. Electronic address: eopara@wakehealth.edu.
authors.forename: Emmanuel C
authors.initials: EC
authors.lastname: Opara
mesh_terms: D000818:Animals; D005260:Female; D052776:Female Urogenital Diseases / Q000628:therapy*; D006801:Humans; D044968:Regenerative Medicine; D023822:Tissue Engineering; D014566:Urogenital System
keywords: Fertility; Hormone replacement; Regenerative medicine; Reproductive system; Tissue engineering