title: A molecule-imprinted polyaniline membrane modified on carbon fiber for detection of glycine.
abstract: A layer of L-glycine-molecule-imprinted polyaniline (LMIP-PANI) polymer film has been modified on a carbon fiber electrode for the determination of L-glycine standard samples and L-glycine in cerebrospinal fluid of wistar mice. It has been found that a linear relationship exists between current and concentration for the glycine standard samples in the range of 0-12 μM by using the LMIP-PANI-modified carbon fiber electrode as a sensor. However, there is no any relationship between current and concentration for the carbon fiber electrode modified with no-glycine-molecule-imprinted polyaniline (NIP-PANI). The MIP-PANI- and NIP-PANI-modified carbon fiber films have been characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and electrochemistry methods. The investigation shows that the MIP-PANI-imprinted carbon fiber electrode will have a potential application in in-situ monitoring neurotransmitter due to its easy fabrication, low cost, bio-compatibility and flexibility.
authors.affiliation: School of Life Science and Technology, University of Electronic Science and Technology of China (UESTC), Jianshe Road, Chengdu 610054, PR China School of Optoelectronic Information, University of Electronic Science and Technology of China (UESTC), Chengdu 610054, PR China.
authors.forename: Hongjuan
authors.initials: H
authors.lastname: Zeng
authors.forename: Deshun
authors.initials: D
authors.lastname: Wang
authors.forename: Junsheng
authors.initials: J
authors.lastname: Yu
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D015374:Biosensing Techniques; D002244:Carbon / Q000737:chemistry*; D000077482:Carbon Fiber; D002851:Chromatography, High Pressure Liquid; D004563:Electrochemistry; D004566:Electrodes; D005260:Female; D005998:Glycine / Q000134:cerebrospinal fluid* / Q000737:chemistry*; D008297:Male; D008567:Membranes, Artificial; D008855:Microscopy, Electron, Scanning; D056951:Photoelectron Spectroscopy; D011108:Polymers / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000814:Aniline Compounds; D001672:Biocompatible Materials; D000077482:Carbon Fiber; D008567:Membranes, Artificial; D011108:Polymers; C416807:polyaniline; D002244:Carbon; D005998:Glycine
keywords: Glycine; cerebrospinal fluid; film; imprint; polyaniline