title: A cancer-associated Epstein-Barr virus variant with epithelial tropism.
abstract: A recent study has identified an Epstein-Barr virus variant from nasopharyngeal carcinoma with unusually high tropism for epithelial cells and low tropism for B cells, as well as a propensity to enter the lytic cycle in both cell types. The results suggest the existence of EBV variants with increased cancer risk.
authors.affiliation: Department of Molecular Genetics, University of Toronto, Toronto, Canada M5S 1A8. Electronic address: lori.frappier@utoronto.ca.
authors.forename: Lori
authors.initials: L
authors.lastname: Frappier
mesh_terms: D002277:Carcinoma; D004847:Epithelial Cells / Q000821:virology*; D020031:Epstein-Barr Virus Infections / Q000821:virology*; D014644:Genetic Variation; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000502:physiology*; D006801:Humans; D000077274:Nasopharyngeal Carcinoma; D009303:Nasopharyngeal Neoplasms / Q000821:virology*; D013045:Species Specificity; D056189:Viral Tropism