title: Synthesis of nonadeuterated 1α,25-dihydroxyvitamin D2.
abstract: An efficient convergent synthesis of nonadeuterated 1α,25-dihydroxyvitamin D2 (1) by Pd(0)-catalyzed coupling between the boronate ester (upper fragment) and the enol triflate (A-ring fragment) is described. This article is part of a Special Issue entitled '16th Vitamin D Workshop'.
authors.affiliation: Departamento de Química Orgánica, Laboratorio de Investigación "Ignacio Ribas", Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Sigüeiro
authors.affiliation: Departamento de Química Orgánica, Laboratorio de Investigación "Ignacio Ribas", Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Álvarez
authors.affiliation: Departamento de Química Orgánica, Laboratorio de Investigación "Ignacio Ribas", Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Otero
authors.affiliation: Departamento de Química Orgánica, Laboratorio de Investigación "Ignacio Ribas", Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
authors.forename: B
authors.initials: B
authors.lastname: López-Pérez
authors.affiliation: Departamento de Química Orgánica, Laboratorio de Investigación "Ignacio Ribas", Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Carballa
authors.affiliation: Departamento de Química Orgánica, Laboratorio de Investigación "Ignacio Ribas", Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Regueira
authors.affiliation: Departamento de Química Orgánica, Laboratorio de Investigación "Ignacio Ribas", Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
authors.forename: P
authors.initials: P
authors.lastname: González-Berdullas
authors.affiliation: Departamento de Fisiología-CIMUS, Laboratorio de Endocrinología Oncológica, Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Seoane
authors.affiliation: Departamento de Fisiología-CIMUS, Laboratorio de Endocrinología Oncológica, Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Pérez-Fernández
authors.affiliation: Departamento de Química Orgánica, Laboratorio de Investigación "Ignacio Ribas", Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Mouriño
authors.affiliation: Departamento de Química Fundamental, Universidad de A Coruña, E-15071 A Coruña, Spain. Electronic address: miguel.maestro@udc.es.
authors.forename: M A
authors.initials: MA
authors.lastname: Maestro
mesh_terms: D002117:Calcitriol / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D060326:Chemistry Techniques, Synthetic; D003903:Deuterium / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D010165:Palladium; D003903:Deuterium; D002117:Calcitriol
keywords: 1α,25-Dihydroxyvitamin D(2) d(9); Isotopic labelling; Vitamin D(2) analogues synthesis