title: Combination therapy with anti-CD6 and oral insulin immunization reverses recent onset diabetes in non obese diabetic mice but fails to induce lasting tolerance.
authors.affiliation: La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA.
authors.forename: Darius A
authors.initials: DA
authors.lastname: Schneider
authors.forename: Ghanashyam
authors.initials: G
authors.lastname: Sarikonda
authors.forename: Enrique
authors.initials: E
authors.lastname: Montero
authors.forename: Matthias G
authors.initials: MG
authors.lastname: von Herrath
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000906:Antibodies / Q000494:pharmacology*; D015703:Antigens, CD / Q000276:immunology*; D000945:Antigens, Differentiation, T-Lymphocyte / Q000276:immunology*; D001786:Blood Glucose / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy* / Q000276:immunology; D004359:Drug Therapy, Combination; D005260:Female; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D007108:Immune Tolerance; D007114:Immunization; D007328:Insulin / Q000008:administration & dosage*; D051379:Mice; D016688:Mice, Inbred NOD
chemical_list: D000906:Antibodies; D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D001786:Blood Glucose; C062279:CD6 antigen; D007004:Hypoglycemic Agents; D007328:Insulin
keywords: ALCAM; Antigen specific therapy; CD6; Immunization; Immunology; NOD; Oral insulin; Type 1 diabetes