title: Gating pluripotency via nuclear pores.
abstract: In recent years, growing evidence has pointed to the interesting idea that pluripotency might be regulated by a nuclear-pore-coordinated network that controls the level of pluripotency factors in the nucleus. A thorough understanding of this process might improve our comprehension of cell pluripotency and differentiation during embryogenesis, as well as aiding the development of novel models for studying human diseases.
authors.affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
authors.forename: Jiping
authors.initials: J
authors.lastname: Yang
authors.affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Cai
authors.affiliation: Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
authors.forename: Fei
authors.initials: F
authors.lastname: Yi
authors.affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Beijing Institute for Brain Disorders, Beijing, China. Electronic address: ghliu@ibp.ac.cn.
authors.forename: Guang-Hui
authors.initials: GH
authors.lastname: Liu
authors.affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: jqu@moon.ibp.ac.cn.
authors.forename: Jing
authors.initials: J
authors.lastname: Qu
authors.affiliation: Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA; Center for Regenerative Medicine in Barcelona, Dr. Aiguader 88, 08003 Barcelona, Spain. Electronic address: belmonte@salk.edu.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Izpisua Belmonte
mesh_terms: D021581:Active Transport, Cell Nucleus; D000818:Animals; D002454:Cell Differentiation; D002467:Cell Nucleus / Q000378:metabolism; D047108:Embryonic Development / Q000502:physiology; D006801:Humans; D022022:Nuclear Pore / Q000502:physiology*; D011485:Protein Binding; D011499:Protein Processing, Post-Translational; D021381:Protein Transport