title: Cerebral activation and lateralization due to the cognition of a various driving speed difference: an fMRI study.
abstract: This study investigated the changes of cerebral activation and lateralization due to the cognition of three driving speeds in comparison to a reference driving speed using functional magnetic resonance imaging fMRI. A driving video as a visual stimulation source was recorded with four different driving speeds in a real driving situation. The experiment consisted of three blocks and each block included a one-minute control phase and a one-minute stimulation phase. The activation area and the lateralization index were analyzed by subtracting high speed data from low speed data. Such areas as occipital, parietal and frontal lobes, which is related to visual cognition, high order visual and spatial attention (or vigilance), were activated due to the cognition of various driving speed differences. As the driving speed difference increased, the activation area increased in the areas related to spatial attention (or vigilance), such as the frontal lobe, however, changes of neuronal activation in the occipital and parietal lobes were inconsistent. As the driving speed difference increased, the absolute value of cerebral lateralization decreased. These results may provide some basic data for elucidating the brain-function mechanism related to the cognition of a various driving speed difference based on a realistic visual stimulation.
authors.affiliation: Department of Biomedical Engineering, Research Institute of Biomedical Engineering, College of Biomedical & Health Science, Konkuk University, Chungju, South Korea.
authors.forename: Hyung-Sik
authors.initials: HS
authors.lastname: Kim
authors.forename: Mi-Hyun
authors.initials: MH
authors.lastname: Choi
authors.forename: Hee-Jeong
authors.initials: HJ
authors.lastname: Yoon
authors.forename: Hyun-Joo
authors.initials: HJ
authors.lastname: Kim
authors.forename: Ul-Ho
authors.initials: UH
authors.lastname: Jeoung
authors.forename: Sung-Jun
authors.initials: SJ
authors.lastname: Park
authors.forename: Dae-Woon
authors.initials: DW
authors.lastname: Lim
authors.forename: Soon-Cheol
authors.initials: SC
authors.lastname: Chung
authors.forename: Beob-Yi
authors.initials: BY
authors.lastname: Lee
mesh_terms: D000328:Adult; D001288:Attention; D001334:Automobile Driving; D001921:Brain / Q000473:pathology*; D001931:Brain Mapping / Q000379:methods*; D003071:Cognition; D003198:Computer Simulation; D005260:Female; D005625:Frontal Lobe / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D009778:Occipital Lobe / Q000473:pathology; D010296:Parietal Lobe / Q000473:pathology; D013997:Time Factors; D014741:Video Recording; D014785:Vision, Ocular; D055815:Young Adult
keywords: Cerebral activation; Cerebral lateralization; Driving speed difference; fMRI