title: Earlier detection can help avoid many serious complications of peripartum cardiomyopathy.
abstract: Peripartum cardiomyopathy (PPCM) has a remarkable potential for recovery. It may be within our capability to help almost all women with PPCM not only to survive, but also to completely recover heart function. Time-of-diagnosis left ventricular ejection fraction (LVEF) ≥0.35 is associated with better survival rates and higher full recovery rates. Increased mortality, chronic cardiomyopathy, thromboembolic complications and serious ventricular tachyarrhythmias are associated with diagnostic LVEF <0.30. Delays in diagnosis may result in lower LVEF at diagnosis and subsequent lower recovery rates. Greater awareness of the possibility of heart failure developing in previously healthy young women, with no history of heart disease, will contribute to earlier diagnosis, with potentially better preserved heart function. Women of African descent may be at higher risk for poorer outcomes. Recent investigations suggest newer biomarkers may help with earlier detection of PPCM.
authors.affiliation: Hospital Albert Schweitzer, Deschapelles, Haiti, c/o 2331 Mt Hood Ct SE, Lacey, WA 98503, USA and Peripartum Cardiomyopathy Network, USA, Investigations in Pregnancy Associated Cardiomyopathy, Central Office, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. fett.sprunger@comcast.net.
authors.forename: James D
authors.initials: JD
authors.lastname: Fett
mesh_terms: D009202:Cardiomyopathies / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D003935:Diagnostic Techniques, Cardiovascular; D042241:Early Diagnosis; D005260:Female; D014943:Global Health; D006801:Humans; D015994:Incidence; D058725:Peripartum Period; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis* / Q000503:physiopathology; D011379:Prognosis; D020127:Recovery of Function; D015996:Survival Rate / Q000639:trends; D013923:Thromboembolism / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D016277:Ventricular Function, Left; D016387:Women's Health