title: Somatostatin receptor molecular imaging for metastatic intracranial hemangiopericytoma.
abstract: Intracranial hemangiopericytomas (HPCs) are rare tumors that closely mimic meningiomas. However, in contrast to meningiomas, HPCs have a relatively high incidence of local recurrence and distant metastases, manifesting the need for sensitive noninvasive methods of detection that efficiently image the entire body. We present a rare case of a right optic nerve sheath HPC in which we identified a previously unknown distant metastasis in the thoracic spine on an 111In-pentetreotide scan. We detail the radiologic characteristics seen with somatostatin receptor imaging, FDG PET, and MRI and discuss how to exploit these findings to detect recurrence and metastatic disease in HPC.
authors.affiliation: From the *Department of Radiology, †Section on Hematology and Oncology, Department of Internal Medicine, and ‡Department of Neurosurgery, Wake Forest School of Medicine, Winston-Salem, NC.
authors.forename: Gopi
authors.initials: G
authors.lastname: Kota
authors.forename: Pushpender
authors.initials: P
authors.lastname: Gupta
authors.forename: Glenn J
authors.initials: GJ
authors.lastname: Lesser
authors.forename: John A
authors.initials: JA
authors.lastname: Wilson
authors.forename: Akiva
authors.initials: A
authors.lastname: Mintz
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006393:Hemangiopericytoma / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis; D017481:Receptors, Somatostatin / Q000378:metabolism*
chemical_list: D017481:Receptors, Somatostatin