title: Salvage esophagectomy in the management of recurrent or persistent esophageal carcinoma.
abstract: Salvage esophagectomy is a viable treatment option in the management of recurrent or persistent esophageal cancer and can be performed with acceptable morbidity and mortality in a select group of patients. Patient selection should include a complete restaging evaluation, cardiopulmonary testing, and an assessment of functional status. A majority of patients with persistent or recurrent esophageal cancer are not candidates for salvage resection. Carefully selected patients undergoing a salvage resection can have outcomes similar to those undergoing a planned esophagectomy after definitive chemoradiotherapy.
authors.affiliation: Division of Thoracic Surgery, Hackensack University Medical Center, 30 Prospect Avenue, Hackensack, NJ, USA.
authors.forename: Jenifer
authors.initials: J
authors.lastname: Marks
authors.forename: David C
authors.initials: DC
authors.lastname: Rice
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Swisher
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D059248:Chemoradiotherapy; D004938:Esophageal Neoplasms / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D016629:Esophagectomy; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D009367:Neoplasm Staging; D018579:Patient Selection; D016879:Salvage Therapy
keywords: Adenocarcinoma; Chemotherapy; Esophagectomy; Radiation; Salvage; Squamous