title: Histological sections of corneal incisions in OCT-guided femtosecond laser cataract surgery.
abstract: OBJECTIVE
  To investigate the quality and accuracy of three-dimensional spectral-domain optical coherence tomography (OCT)-guided corneal incisions with the Catalys precision femtosecond laser system (OptiMedica, Sunnyvale, CA) in living human tissue.
  
  
  METHODS
  In vivo cataract and intrastromal corneal incisions were made with a femtosecond laser designed for cataract surgery with a patient scheduled for enucleation.
  
  
  RESULTS
  An accurate correlation between the pre-incision spectral-domain OCT and the post-incision histology was demonstrated.
  
  
  CONCLUSIONS
  The OCT-guided femtosecond laser is capable of creating accurate, precise, and histologically demonstrable incisions in preselected intrastromal locations.
authors.forename: Tim
authors.initials: T
authors.lastname: Schultz
authors.forename: Iris
authors.initials: I
authors.lastname: Tischoff
authors.forename: Edak
authors.initials: E
authors.lastname: Ezeanosike
authors.forename: H Burkhard
authors.initials: HB
authors.lastname: Dick
mesh_terms: D000368:Aged; D002387:Cataract Extraction / Q000379:methods*; D003315:Cornea / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D021621:Imaging, Three-Dimensional; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D064727:Posterior Capsulotomy / Q000379:methods; D041623:Tomography, Optical Coherence; D014945:Wound Healing