title: Culex quinquefasciatus storage proteins.
abstract: Insect storage proteins accumulate at high levels during larval development of holometabolous insects. During metamorphosis they are degraded, supplying energy and amino acids for the completion of adult development. The genome of Culex quinquefasciatus contains eleven storage protein-coding genes. Their transcripts are more abundant in larvae than in pupae and in adults. In fact, only four of these genes are transcribed in adults, two of which in blood-fed adult females but not in adult males. Transcripts corresponding to all Cx. quinquefasciatus storage proteins were detected by RT-PCR, while mass spectrometric analysis of larval and pupal proteins identified all storage proteins with the exception of one encoded by Cq LSP1.8. Our results indicate that the identified Cx. quinquefasciatus storage protein-coding genes are candidates for identifying regulatory sequences for the development of molecular tools for vector control.
authors.affiliation: Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brasil.
authors.forename: Larissa A
authors.initials: LA
authors.lastname: Martins
authors.forename: Andréa C
authors.initials: AC
authors.lastname: Fogaça
authors.forename: A Tania
authors.initials: AT
authors.lastname: Bijovsky
authors.forename: Rebeca
authors.initials: R
authors.lastname: Carballar-Lejarazú
authors.forename: Osvaldo
authors.initials: O
authors.lastname: Marinotti
authors.forename: André F
authors.initials: AF
authors.lastname: Cardoso
mesh_terms: D000818:Animals; D003465:Culex / Q000235:genetics* / Q000254:growth & development*; D005260:Female; D016678:Genome / Q000235:genetics; D019476:Insect Proteins / Q000235:genetics*; D007814:Larva / Q000235:genetics / Q000254:growth & development; D008297:Male; D011679:Pupa / Q000235:genetics / Q000254:growth & development
chemical_list: D019476:Insect Proteins; C041137:storage proteins, Insecta