title: The lysine glycation 1. A preliminary investigation on the products arising from the reaction of protected lysine and D-glucose.
abstract: The nature of the products arising from a 10 days, sterile incubation at 37°C and pH 7.2 of a 1:1 mixture of N-α-(p-tosyl)-lysine-methylesterhydrochloride and anhydrous D-glucose was investigated by fast atom bombardment mass spectrometry and(1)H and(13)C nuclear magnetic resonance spectroscopies. Differently to the reactivity usually described on the basis of other analytical techniques, FAB mass spectrometric measurements indicate the occurrence of the reaction of protected lysine with more than one D-glucose molecule.
authors.affiliation: Istituto di Medicina Interna, Patologia Medica I, Policlinico Universitario, Via Giustiniani 2, I-35100, Padova, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Lapolla
authors.forename: C
authors.initials: C
authors.lastname: Gerhardinger
authors.forename: L
authors.initials: L
authors.lastname: Baldo
authors.forename: D
authors.initials: D
authors.lastname: Fedele
authors.forename: R
authors.initials: R
authors.lastname: Bertani
authors.forename: G
authors.initials: G
authors.lastname: Facchin
authors.forename: E
authors.initials: E
authors.lastname: Rizzi
authors.forename: S
authors.initials: S
authors.lastname: Catinella
authors.forename: R
authors.initials: R
authors.lastname: Seraglia
authors.forename: P
authors.initials: P
authors.lastname: Traldi