title: Copper-catalyzed etherification of arene C-H bonds.
abstract: A method for direct, auxiliary-assisted alkoxylation and phenoxylation of β-sp(2) C-H bonds of benzoic acid derivatives and γ-sp(2) C-H bonds of amine derivatives is reported. The reaction employs (CuOH)2CO3 catalyst, air as an oxidant, phenol or alcohol coupling partner, DMF, pyridine, or DMPU solvent, and K2CO3, tetramethylguanidine, or K3PO4 base at 70-130 °C.
authors.affiliation: Department of Chemistry, University of Houston , Houston, Texas 77204-5003, United States.
authors.forename: James
authors.initials: J
authors.lastname: Roane
authors.forename: Olafs
authors.initials: O
authors.lastname: Daugulis
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D019817:Benzoic Acid / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006860:Hydrogen Bonding; D008760:Methylguanidine / Q000737:chemistry*; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*
chemical_list: D000438:Alcohols; D010636:Phenols; D008760:Methylguanidine; D003300:Copper; D019817:Benzoic Acid