title: Developments in large and midsize vasculitis.
abstract: Childhood vasculitis is a complex and fascinating area in pediatric rheumatology that has experienced an unprecedented surge in research, leading to new knowledge over the past several years. Vasculitis is defined as the presence of inflammatory cell infiltration in blood vessel walls, usually with multisystemic involvement. The most frequent forms of vasculitis in childhood are the small-size vasculitides, of which Henoch-Schoenlein Purpura and other leucocytoclastic vasculitis are the best examples, followed by Kawasaki disease, a midsize vasculitis, and Takayasu arteritis, a large-size vasculitis, both of which are topics in this article.
authors.affiliation: Department of Pediatrics, Universidade Federal de São Paulo, Rua Borges Lagoa 802, CEP 04038-001, São Paulo, Brazil. Electronic address: teterreri@terra.com.br.
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Terreri
authors.forename: Gleice
authors.initials: G
authors.lastname: Clemente
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D002648:Child; D017023:Coronary Angiography; D006801:Humans; D006973:Hypertension / Q000209:etiology; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D009080:Mucocutaneous Lymph Node Syndrome / Q000175:diagnosis* / Q000628:therapy; D013625:Takayasu Arteritis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D001241:Aspirin
keywords: Adolescents; Childhood; Coronary artery; Hypertension; Imaging; Kawasaki; Takayasu’s arteritis; Vasculitis