title: Allergy to cosmetics: a literature review.
abstract: The term cosmetic has a broad definition and includes personal care products, hair care products, nail care products, and sunscreens. Modern cosmetics are safe for most users, and adverse reactions are very rare because the manufacturers invest heavily in safety, quality control, and product testing before releasing the product to the market. Despite these efforts, adverse reactions occur. Skin care products are major contributors to cosmetic allergic contact dermatitis (ACD), followed by hair care and nail care products. The most common allergens are fragrances and preservatives. The diagnosis of cosmetic allergy is established by reviewing the patient's clinical history and physical examination findings and confirmed with skin patch testing. Patch testing is the standard method for detecting allergens responsible for eliciting ACD. The purpose of this article was to review the prevalence, legislative laws, and role of patch testing in ACD.
authors.affiliation: From the *Mayo Clinic Rochester, Rochester, MN, and †Arizona Mayo Clinic, Scottsdale, AZ.
authors.forename: Jennifer I
authors.initials: JI
authors.lastname: Alani
authors.forename: Mark Denis P
authors.initials: MD
authors.lastname: Davis
authors.forename: James A
authors.initials: JA
authors.lastname: Yiannias
mesh_terms: D000485:Allergens / Q000009:adverse effects* / Q000145:classification; D004396:Coloring Agents / Q000009:adverse effects; D003358:Cosmetics / Q000009:adverse effects* / Q000145:classification; D017449:Dermatitis, Allergic Contact / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D006202:Hair Dyes / Q000009:adverse effects; D006801:Humans; D010328:Patch Tests / Q000379:methods; D010476:Perfume / Q000009:adverse effects; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects* / Q000145:classification; D015995:Prevalence; D012307:Risk Factors; D013501:Surface-Active Agents / Q000009:adverse effects
chemical_list: D000485:Allergens; D004396:Coloring Agents; D003358:Cosmetics; D006202:Hair Dyes; D010476:Perfume; D011310:Preservatives, Pharmaceutical; D013501:Surface-Active Agents