title: Bilateral primary xanthoma of the humeri with pathologic fractures: A case report.
abstract: Xanthomas are rare bone tumors that occur more often in the appendicular skeleton and typically appear radiographically benign, with a narrow zone of transition and a sclerotic rim. We report the case of a 57-year-old woman with hyperlipidemia presenting with bilateral shoulder pain after minor trauma. Radiographic and histopathologic investigation demonstrated intraosseous xanthoma with atypical features, including multifocality, a wide zone of transition and pathologic fractures-characteristics more commonly associated with aggressive lesions such as multiple myeloma or metastasis. The diagnosis, imaging, and histological appearance of xanthoma of bone are reviewed.
authors.affiliation: Sayed Ali, Ali B Syed, Department of Radiology, Temple University Hospital, 3401 N. Broad St. Philadelphia, PA 19140, United States.
authors.forename: Sayed
authors.initials: S
authors.lastname: Ali
authors.forename: Alex
authors.initials: A
authors.lastname: Fedenko
authors.forename: Ali B
authors.initials: AB
authors.lastname: Syed
authors.forename: George
authors.initials: G
authors.lastname: Matcuk
authors.forename: Dakshesh
authors.initials: D
authors.lastname: Patel
authors.forename: Chris
authors.initials: C
authors.lastname: Gottsegen
authors.forename: Eric
authors.initials: E
authors.lastname: White
keywords: Hyperlipidemia; Pathologic fracture; Xanthoma