title: Finding epitopes with computers.
abstract: The goal of structural vaccinology is to enable the design and engineering of improved antigens. In a recent issue of Chemistry & Biology, Gourlay and colleagues provided evidence that structure-based computational methods allow prediction of B cell epitopes, a crucial step for antigen selection and optimization in vaccine development.
authors.affiliation: Novartis Vaccines and Diagnostics, 53100 Siena, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Malito
authors.forename: Rino
authors.initials: R
authors.lastname: Rappuoli
mesh_terms: D000942:Antigens, Bacterial / Q000737:chemistry*; D001426:Bacterial Proteins / Q000737:chemistry*; D001428:Bacterial Vaccines / Q000276:immunology*; D016957:Burkholderia pseudomallei / Q000276:immunology*; D000939:Epitopes / Q000737:chemistry*; D006801:Humans
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D001428:Bacterial Vaccines; D000939:Epitopes