title: Noma in an immunocompromised patient.
abstract: Noma (also known as cancrum oris) is classified by the World Health Organization as a necrotizing ulcerative stomatitis, an invasive acute infection which affects the orofacial tissues. Patients who are subject to such risk factors as severe malnutrition or alteration of the immune system are predominantly affected. This article presents a case of noma in a 62-year-old immunocompromised patient with pain and tooth mobility in the mandibular region, ulceration, bleeding, gingival inflammatory secretion, and oral malodor. The signs and symptoms were controlled only after the intravenous administration of 500 mg tid of imipenem/cilastatin sodium and 2 g qd of vancomycin. After infection control was maintained, the patient was directed to surgery for removal of bone sequestration and curettage of the maxillary sinus. The patient was prescribed 1 g qd of oral clindamycin for 3 months postsurgery.
authors.forename: Igor Henrique Morais
authors.initials: IH
authors.lastname: Silva
authors.forename: Andreza Barkokebas S de
authors.initials: AB
authors.lastname: Faria
authors.forename: Deborah Daniela Diniz
authors.initials: DD
authors.lastname: Fonseca
authors.forename: Carlos Menezes
authors.initials: CM
authors.lastname: Aguiar
authors.forename: Alessandra Tavares
authors.initials: AT
authors.lastname: Carvalho
authors.forename: Luiz Alcino
authors.initials: LA
authors.lastname: Gueiros
authors.forename: Jair Carneiro
authors.initials: JC
authors.lastname: Leao
mesh_terms: D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008875:Middle Aged; D009625:Noma / Q000175:diagnosis* / Q000276:immunology