title: Robust GRAPPA reconstruction using sparse multi-kernel learning with least squares support vector regression.
abstract: Accuracy of interpolation coefficients fitting to the auto-calibrating signal data is crucial for k-space-based parallel reconstruction. Both conventional generalized autocalibrating partially parallel acquisitions (GRAPPA) reconstruction that utilizes linear interpolation function and nonlinear GRAPPA (NLGRAPPA) reconstruction with polynomial kernel function are sensitive to interpolation window and often cannot consistently produce good results for overall acceleration factors. In this study, sparse multi-kernel learning is conducted within the framework of least squares support vector regression to fit interpolation coefficients as well as to reconstruct images robustly under different subsampling patterns and coil datasets. The kernel combination weights and interpolation coefficients are adaptively determined by efficient semi-infinite linear programming techniques. Experimental results on phantom and in vivo data indicate that the proposed method can automatically achieve an optimized compromise between noise suppression and residual artifacts for various sampling schemes. Compared with NLGRAPPA, our method is significantly less sensitive to the interpolation window and kernel parameters.
authors.affiliation: School of Automation Engineering, University of Electronic Science and Technology of China, Chengdu, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Xu
authors.forename: Yanqiu
authors.initials: Y
authors.lastname: Feng
authors.forename: Xiaoyun
authors.initials: X
authors.lastname: Liu
authors.forename: Lili
authors.initials: L
authors.lastname: Kang
authors.forename: Wufan
authors.initials: W
authors.lastname: Chen
mesh_terms: D000465:Algorithms; D016477:Artifacts; D001921:Brain / Q000473:pathology; D002138:Calibration; D017143:Fuzzy Logic; D064368:Healthy Volunteers; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D016018:Least-Squares Analysis; D008279:Magnetic Resonance Imaging / Q000379:methods; D015233:Models, Statistical; D009206:Myocardium / Q000473:pathology; D019047:Phantoms, Imaging; D060388:Support Vector Machine
keywords: GRAPPA; Multi-kernel learning; Parallel imaging; Structural risk minimization; Support vector regression (SVR)