title: Correlations of linear and nonlinear ultrasound parameters with density and microarchitectural parameters in trabecular bone.
abstract: In the present study, correlations of linear and nonlinear ultrasound parameters (speed of sound, normalized broadband ultrasound attenuation, and nonlinear parameter B/A) with bone mineral density and microarchitectural parameters were investigated in 28 bovine femoral trabecular bone samples in vitro. All three ultrasound parameters exhibited relatively high correlation coefficients with the indexes of bone quantity (bone mineral density and bone volume fraction) and lower correlation coefficients with the remaining microarchitectural parameters. These results suggest that B/A, in addition to speed of sound and attenuation, may have potential as an index for the assessment of bone status and osteoporosis.
authors.affiliation: Department of Physics, Kangwon National University, Chuncheon 200-701, Republic of Korea acustica@kangwon.ac.kr.
authors.forename: Kang Il
authors.initials: KI
authors.lastname: Lee
mesh_terms: D000818:Animals; D015519:Bone Density; D002417:Cattle; D004867:Equipment Design; D005269:Femur / Q000000981:diagnostic imaging*; D016014:Linear Models; D009038:Motion; D017711:Nonlinear Dynamics; D010024:Osteoporosis / Q000000981:diagnostic imaging; D012815:Signal Processing, Computer-Assisted; D013016:Sound; D013997:Time Factors; D014159:Transducers; D014465:Ultrasonics / Q000295:instrumentation / Q000379:methods*; D014463:Ultrasonography