title: Transcatheter aortic valve replacement for aortic bioprosthetic valve failure with cardiogenic shock.
abstract: Acutely failing bioprosthetic valves represent a clinical emergency and are exceedingly challenging given the paucity of therapeutic options. Oftentimes, these patients are not re-operative candidates due to clinical instability. We present 2 cases of acute degenerative aortic bioprosthetic valve failure with cardiogenic shock treated with transcatheter aortic valve replacement (TAVR). These cases were characterized by hemodynamic instability with vasopressor dependence and (multiple) organ failure. These 2 cases demonstrate that TAVR should be considered as a treatment option for unstable patients with bioprosthetic failure.
authors.affiliation: Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 USA. marat.fudim@vanderbilt.edu.
authors.forename: Marat
authors.initials: M
authors.lastname: Fudim
authors.forename: Roshanak R
authors.initials: RR
authors.lastname: Markley
authors.forename: Mark A
authors.initials: MA
authors.lastname: Robbins
mesh_terms: D000369:Aged, 80 and over; D001021:Aortic Valve / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000601:surgery*; D001705:Bioprosthesis / Q000009:adverse effects*; D006328:Cardiac Catheterization / Q000379:methods*; D004452:Echocardiography; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D013902:Radiography, Thoracic; D012086:Reoperation / Q000379:methods; D012770:Shock, Cardiogenic / Q000209:etiology* / Q000601:surgery