title: Electrocardiographic left ventricular hypertrophy criteria and ambulatory blood pressure monitoring parameters in adults.
abstract: BACKGROUND
  To examine the relationship between ambulatory blood pressure monitoring parameters (ABPM) and electrocardiographic criteria for left-ventricular hypertrophy (LVH) in adults.
  
  
  METHODS
  This study analyzed 1,544 subjects from the EVIDENT study (mean age = 55 ± 14 years; 61% women). A standard electrocardiograph (ECG) and 10 criteria were used to detect LVH. Office and ABPM were performed, and we analyzed 24-hour systolic blood pressure (SBP) and diastolic blood pressure (DBP), percentage of time awake with SBP ≥135 mm Hg, percentage of time asleep with SBP ≥120 mm Hg, and central aortic blood pressure.
  
  
  RESULTS
  LVH according to some electrocardiographic criteria was found in 11.30% of the patients (16.60% of men and 7.70% of women). The patients with LVH were older; had higher values for office, 24-hour and, central aortic blood pressure; were more likely to be men; and had a higher prevalence of obesity, diabetes, and antihypertensive or lipid-lowering drug use. In the logistic regression analysis, the association between the parameters of ABPM and LVH, after adjusting for age, sex, body mass index, and heart rate, remained statistically significant.
  
  
  CONCLUSIONS
  Twenty-four hour blood pressure, the percentage of time with elevated awake and asleep SBPs, and the central systolic blood pressure are related to the presence of LVH as determined by ECG in adults. These results indicate the potential importance of the monitoring and control of different 24-hour parameters of blood pressure in addition to the standard clinic blood pressure with respect to the development of LVH.
  
  
  BACKGROUND
  ClinicalTrials.gov identifier NCT01325064.
authors.affiliation: Primary Care Research Unit, Alamedilla Health Center, REDIAPP, IBSAL, Salamanca, Spain.
authors.forename: Manuel A
authors.initials: MA
authors.lastname: Gómez-Marcos
authors.forename: Jose I
authors.initials: JI
authors.lastname: Recio-Rodríguez
authors.forename: María C
authors.initials: MC
authors.lastname: Patino-Alonso
authors.forename: Cristina
authors.initials: C
authors.lastname: Agudo-Conde
authors.forename: Carmen
authors.initials: C
authors.lastname: Fernandez-Alonso
authors.forename: Vicente
authors.initials: V
authors.lastname: Martinez Vizcaino
authors.forename: Carlos Martin
authors.initials: CM
authors.lastname: Cantera
authors.forename: Nahia
authors.initials: N
authors.lastname: Guenaga-Saenz
authors.forename: Natividad
authors.initials: N
authors.lastname: González-Viejo
authors.forename: Luis
authors.initials: L
authors.lastname: García-Ortiz
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D016009:Chi-Square Distribution; D002940:Circadian Rhythm; D015897:Comorbidity; D003430:Cross-Sectional Studies; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis* / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011237:Predictive Value of Tests; D015995:Prevalence; D012307:Risk Factors; D012890:Sleep; D013030:Spain / Q000453:epidemiology; D013997:Time Factors
keywords: arterial stiffness; blood pressure; cardiovascular disease; hypertension; left-ventricular hypertrophy.