title: Nausea and vomiting in advanced cancer.
abstract: Nausea and vomiting are very common symptoms in cancer both treatment and non-treatment related. Many complications of advanced cancer such as gastroparesis, bowel and outlet obstructions, and brain tumors may have nausea and vomiting or either symptom alone. In a non-obstructed situation, nausea may be more difficult to manage and is more objectionable to patients. There is little research on management of these symptoms except the literature on chemotherapy induced nausea where guidelines exist. This article will review the etiologies of nausea and vomiting in advanced cancer and the medications which have been used to treat them. An etiology based protocol to approach the symptom is outlined.
authors.affiliation: The Harry R. Horvitz Center for Palliative Medicine(1), Section of Palliative Medicine and Supportive Oncology, Department of Solid Tumor Oncology, Cleveland Clinic Taussig Cancer Institute(2), Cleveland, OH 44195, USA.
authors.forename: Pamela
authors.initials: P
authors.lastname: Gordon
authors.affiliation: The Harry R. Horvitz Center for Palliative Medicine(1), Section of Palliative Medicine and Supportive Oncology, Department of Solid Tumor Oncology, Cleveland Clinic Taussig Cancer Institute(2), Cleveland, OH 44195, USA. Electronic address: legrans@ccf.org.
authors.forename: Susan B
authors.initials: SB
authors.lastname: LeGrand
authors.affiliation: The Harry R. Horvitz Center for Palliative Medicine(1), Section of Palliative Medicine and Supportive Oncology, Department of Solid Tumor Oncology, Cleveland Clinic Taussig Cancer Institute(2), Cleveland, OH 44195, USA.
authors.forename: Declan
authors.initials: D
authors.lastname: Walsh
mesh_terms: D006801:Humans; D009325:Nausea / Q000139:chemically induced / Q000150:complications* / Q000188:drug therapy / Q000628:therapy; D009369:Neoplasms / Q000150:complications* / Q000188:drug therapy; D014839:Vomiting / Q000139:chemically induced / Q000150:complications* / Q000188:drug therapy / Q000628:therapy
keywords: Cancer; Nausea; Palliative medicine; Vomiting