title: Fluorescence modification of the AAAA (4A) loop: toward a probe of the structural dynamics of the i-motif of the retinoblastoma gene.
abstract: Systematic modification of the 4A loop region of the Rb gene with (Py)A fluorophore units allows discrimination of the fluorescence signals corresponding to structural dynamics from single-stranded to i-motif structures.
authors.affiliation: Department of Chemistry, BK School of Molecular Science, Pohang University of Science and Technology, Pohang 790-784, South Korea. bhkim@postech.ac.kr.
authors.forename: Jung Woo
authors.initials: JW
authors.lastname: Park
authors.forename: Young Jun
authors.initials: YJ
authors.lastname: Seo
authors.forename: Byeang Hyean
authors.initials: BH
authors.lastname: Kim
mesh_terms: D001483:Base Sequence; D059372:Nucleotide Motifs; D016160:Retinoblastoma Protein / Q000737:chemistry* / Q000235:genetics*; D013050:Spectrometry, Fluorescence
chemical_list: D016160:Retinoblastoma Protein