title: Putative sites of cytokinin action during their enhancing effect on indole alkaloid accumulation in periwinkle cell suspensions.
abstract: The effects of cytokinins on the different branches of the indole alkaloid pathway were investigated in Catharanthus roseus cell cultures. Addition of zeatin to a 2,4-dichlorophenoxyacetic acid-containing medium decreased tryptamine levels and increased the bioconversion of secologanin to ajmalicine. Zeatin also enhanced the geraniol-10 hydroxylase activities and modified the indole alkaloid pattern. The results are discussed in the light of previous works showing that cytokinins have a positive effect on indole alkaloid accumulation in some lines of C. roseus.
authors.affiliation: Laboratoire de Biologie Cellulaire et Biochimie Végétale, Faculté de Pharmacie, Université de Tours, 37200, Tours, France.
authors.forename: A
authors.initials: A
authors.lastname: Decendit
authors.forename: G
authors.initials: G
authors.lastname: Petit
authors.forename: F
authors.initials: F
authors.lastname: Andreu
authors.forename: P
authors.initials: P
authors.lastname: Doireau
authors.forename: J M
authors.initials: JM
authors.lastname: Mérillon
authors.forename: M
authors.initials: M
authors.lastname: Rideau