title: Endoscopic transnasal resection of ameloblastoma with intracranial extension.
abstract: Ameloblastoma is a rare odontogenic tumor with characteristics of epithelial tissue that produces enamel for the developing tooth. This lesion is generally considered benign, but has malignant forms that invade locally and metastasize. We present a 60-year-old man with maxillary ameloblastoma that after multiple recurrences developed intracranial extension with dural involvement of the middle cranial fossa and was treated by endoscopic transnasal resection followed by radiation therapy. Our technique and intraoperative findings are described with a review of the literature on intracranial ameloblastoma. This patient represents a unique account of endoscopic transnasal resection being utilized in the treatment of intracranial extension of ameloblastoma and demonstrates potential for application in similar cases.
authors.affiliation: Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52245, USA.
authors.forename: Royce W
authors.initials: RW
authors.lastname: Woodroffe
authors.affiliation: Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52245, USA. Electronic address: taylor-abel@uiowa.edu.
authors.forename: Taylor J
authors.initials: TJ
authors.lastname: Abel
authors.affiliation: Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
authors.forename: Aaron
authors.initials: A
authors.lastname: Fletcher
authors.affiliation: Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52245, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Grossbach
authors.affiliation: Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
authors.forename: Douglas J
authors.initials: DJ
authors.lastname: Van Daele
authors.affiliation: Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
authors.forename: Erin
authors.initials: E
authors.lastname: O'Brien
authors.affiliation: Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52245, USA; Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
authors.forename: Jeremy D W
authors.initials: JD
authors.lastname: Greenlee
mesh_terms: D000564:Ameloblastoma / Q000175:diagnosis / Q000601:surgery*; D001932:Brain Neoplasms / Q000175:diagnosis / Q000601:surgery*; D004724:Endoscopy / Q000379:methods*; D006801:Humans; D007573:Jaw Neoplasms / Q000175:diagnosis / Q000601:surgery*; D008297:Male; D008875:Middle Aged
keywords: Approach; Dental tumor; Endoscopy; Skull base