title: A case of possible HIV prophylaxis-induced anxiety and obsessive-compulsive disorder.
abstract: There is considerable literature on the neuropsychiatric effects of antiretrovirals. This is the first case, to our knowledge, of new-onset obsessive-compulsive symptoms correlated with emtricitabine/tenofovir, a commonly prescribed HIV prophylaxis combination. We describe the case of a woman, who developed upsetting obsessive thoughts following initiation of this pharmacotherapy and include discussion of relevant literature.
authors.affiliation: UT Southwestern Psychiatry Residency at the Seton Family of Hospitals, Austin, Texas, USA. Electronic address: ajhauptman@seton.org.
authors.forename: Aaron
authors.initials: A
authors.lastname: Hauptman
authors.forename: Lisa
authors.initials: L
authors.lastname: Carchedi
mesh_terms: D000225:Adenine / Q000009:adverse effects / Q000031:analogs & derivatives*; D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects*; D001008:Anxiety Disorders / Q000139:chemically induced; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives*; D000068679:Emtricitabine; D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000139:chemically induced*; D063065:Organophosphonates / Q000009:adverse effects*; D000068698:Tenofovir
chemical_list: D019380:Anti-HIV Agents; D063065:Organophosphonates; D003841:Deoxycytidine; D000068698:Tenofovir; D000068679:Emtricitabine; D000225:Adenine
keywords: ADE; Adverse event; Antiretroviral; Anxiety; HIV; Neuropsychiatry; Obsessive–Compulsive disorder; Side effect