title: [What is the benefit of salt reduction on blood pressure? Assessment of the Cochrane Review: Effect of longer-term modest salt reduction on blood pressure. He FJ, Li J, Macgregor GA. Cochrane Database Syst Rev. 2013 Apr 30;4:CD004937].
abstract: In the present article we evaluate and comment the systematic review from Cochrane Collaboration "Effect of longer-term modest salt reduction on blood pressure. Cochrane Database Syst Rev. 2013 Apr 30;4:CD004937".
  
  
  OBJECTIVE
  What is the impact of long-term (= 4 weeks) modest salt (sodium chloride) reduction on arterial blood pressure?
  
  
  CONCLUSIONS
  This systematic review concluded that a moderate reduction in salt intake (mean reduction -4.4 g per day) resulted in statistically significant decreases in blood pressure (BP) that may be helpful in normotensive (-2.42 mmHg systolic BP; -1.00 mmHg diastolic BP) and hypertensive patients (-5.39 mmHg systolic BP; -2.82 mmHg diastolic BP). There were slight increases in physiological plasma renin activity, aldosterone and norepinephrine, without significant changes in lipid profile.
authors.affiliation: Laboratório de Farmacologia Clínica e Terapêutica. Faculdade Medicina da Universidade de Lisboa. Lisboa. Portugal.
authors.forename: Daniel
authors.initials: D
authors.lastname: Caldeira
authors.forename: António
authors.initials: A
authors.lastname: Vaz-Carneiro
authors.forename: João
authors.initials: J
authors.lastname: Costa
mesh_terms: D001794:Blood Pressure / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000178:diet therapy*; D012196:Review Literature as Topic; D017673:Sodium Chloride, Dietary / Q000008:administration & dosage*
chemical_list: D017673:Sodium Chloride, Dietary