title: The comprehensive management of pregnant women with major mood disorders: a case study involving phenelzine, lithium, and quetiapine.
abstract: Pregnancy in women with severe mental illness (SMI) often bring added dimensions of complexity; considering that this group of women are choosing to have children at increasing rates, more highly complex cases will require management. A 31-year-old primigravida with a diagnosis of bipolar affective disorder was treated with an antidepressant, mood stabiliser and antipsychotic. This case discusses preconception counselling, pregnancy and labour management that resulted in the delivery of a 4,200 g baby at 39 weeks by emergency caesarian section. This case highlights the collaborative approach to care that is needed in this group of women and the need for increasing awareness and knowledge in health professionals. It follows the management from preconception through to the postpartum period.
authors.affiliation: Childbirth and Mental Illness Antenatal Clinic, King Edward Memorial Hospital, 374 Bagot Road, Subiaco, Perth, WA, 6008, Australia, jacqueline.frayne@health.wa.gov.au.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Frayne
authors.forename: Thinh
authors.initials: T
authors.lastname: Nguyen
authors.forename: Rolland
authors.initials: R
authors.lastname: Kohan
authors.forename: Nick
authors.initials: N
authors.lastname: De Felice
authors.forename: Jonathan
authors.initials: J
authors.lastname: Rampono
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D002585:Cesarean Section; D003987:Dibenzothiazepines / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008094:Lithium / Q000627:therapeutic use*; D010624:Phenelzine / Q000009:adverse effects / Q000627:therapeutic use*; D016742:Preconception Care; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D011256:Pregnancy Outcome; D011297:Prenatal Exposure Delayed Effects; D000069348:Quetiapine Fumarate; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate; D008094:Lithium; D010624:Phenelzine