title: Mechanical complications of acute myocardial infarction.
abstract: Acute myocardial infarction (AMI) can result in ischemic, mechanical, arrhythmic, embolic, or inflammatory complications. The development of mechanical complications following AMI is associated with a significantly reduced short-term and long-term survival. Since the introduction of primary percutaneous coronary intervention as the principal reperfusion strategy following acute ST-elevation myocardial infarction, the incidence of mechanical complications, including rupture of the left ventricular free wall, papillary muscle, and ventricular septum, has reduced significantly to less than 1%. Despite high operative mortality, the lack of an effective medical alternative makes surgical repair the mainstay of current management for these patients.
authors.affiliation: Department of Cardiothoracic Surgery, Papworth Hospital, University of Cambridge, Cambridge CB23 3RE, UK.
authors.forename: Ramesh S
authors.initials: RS
authors.lastname: Kutty
authors.forename: Nicola
authors.initials: N
authors.lastname: Jones
authors.forename: Narain
authors.initials: N
authors.lastname: Moorjani
mesh_terms: D006328:Cardiac Catheterization / Q000379:methods; D057791:Cardiac Imaging Techniques; D002316:Cardiotonic Agents / Q000627:therapeutic use; D006342:Heart Rupture, Post-Infarction / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D053208:Kaplan-Meier Estimate; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D009204:Myocardial Revascularization / Q000379:methods; D011182:Postoperative Care / Q000379:methods; D011300:Preoperative Care / Q000379:methods; D016896:Treatment Outcome; D057832:Watchful Waiting
chemical_list: D002316:Cardiotonic Agents
keywords: Acute myocardial infarction; Infarct exclusion technique; Left ventricular free wall rupture; Papillary muscle rupture; Ventricular septal rupture