title: Immune response in severe infection: could life-saving drugs be potentially harmful?
abstract: Critically ill patients suffer a high rate of nosocomial infection with secondary sepsis being a common cause of death. Usage of antibiotics and catecholamines is often necessary, but it can compromise complex immune response to infection. This review explores influence of these life-saving drugs on host immune response to severe infection.
authors.affiliation: Clinic of Anesthesiology and Intensive Therapy, Military Medical Academy, Crnotravska 17, 11000 Belgrade, Serbia ; Faculty of Medicine of the Military Medical Academy, University of Defense, Crnotravska 17, 11000 Belgrade, Serbia.
authors.forename: Maja
authors.initials: M
authors.lastname: Surbatovic
authors.forename: Jasna
authors.initials: J
authors.lastname: Jevdjic
authors.forename: Milic
authors.initials: M
authors.lastname: Veljovic
authors.forename: Nada
authors.initials: N
authors.lastname: Popovic
authors.forename: Dragan
authors.initials: D
authors.lastname: Djordjevic
authors.forename: Sonja
authors.initials: S
authors.lastname: Radakovic
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D002395:Catecholamines / Q000009:adverse effects / Q000627:therapeutic use; D016638:Critical Illness; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D007239:Infections / Q000188:drug therapy / Q000276:immunology*
chemical_list: D000900:Anti-Bacterial Agents; D002395:Catecholamines