title: Biomarkers in canine inflammatory bowel disease diagnostics.
abstract: Canine inflammatory bowel disease (IBD) is a heterogeneous group of chronic gastrointestinal disorders. The etiology, similar to human IBD, remains unknown. Canine IBD is diagnosed by exclusion, which is a long, time and money-consuming process due to the need of elimination of other diseases presenting with similar symptoms. Therefore, a search for a specific and sensitive marker is needed to overcome these difficulties. The article is divided into 3 sections presenting up-to-date information about laboratory markers, immunohistochemical markers and changes in the neurochemical coding of the enteric nervous system, concentrating on their usefulness and future applications. Data concerning laboratory and immunohistochemical markers is based mainly on canine IBD, while the neuroimmunohistochemistry section presents knowledge from human IBD due to the lack of such studies in veterinary medicine.
authors.affiliation: Department of Clinical Diagnostics, Faculty of Veterinary Medicine University of Warmia and Mazury, Oczapowskiego 14, 10-719 Olsztyn, Poland. wdowiak84@gmail.com
authors.forename: M
authors.initials: M
authors.lastname: Wdowiak
authors.forename: A
authors.initials: A
authors.lastname: Rychlik
authors.forename: A
authors.initials: A
authors.lastname: Kołodziejska-Sawerska
mesh_terms: D000818:Animals; D015415:Biomarkers; D004283:Dog Diseases / Q000378:metabolism* / Q000652:urine; D004285:Dogs; D005243:Feces / Q000737:chemistry; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis / Q000378:metabolism / Q000662:veterinary*
chemical_list: D015415:Biomarkers