title: Poly a blocks in the nuclear ribonucleoprotein complexes, containing pre-mRNA.
abstract: Poly A was found in nuclear particles containing pre-mRNA. It was shown that during the isolation of 30S particles from rat liver or Ehrlich ascites carcinoma nuclei, all poly A is detached from the particles containing pre-mRNA and is found in the form of RNP with a sedimentation coefficient of about 14S. When RNP polyparticles are isolated in the presence of RNase inhibitor poly A is distributed among the particles of higher molecular weights.Since the sedimentation properties and buoyant density of the poly A-containing particles are different from the 30S particles it was suggested that the poly A fragments are bound not with informofers, but with another kind of protein.
authors.affiliation: Institute of Molecular Biology, Academy of Sciences of the U.S.S.R., Moscow, USSR.
authors.forename: O P
authors.initials: OP
authors.lastname: Samarina
authors.forename: N A
authors.initials: NA
authors.lastname: Aitkhozhina
authors.forename: J
authors.initials: J
authors.lastname: Besson