Aging is not programmed: genetic pseudo-program is a shadow of developmental growth.
Aging is not and cannot be programmed. Instead, aging is a continuation of developmental growth, driven by genetic pathways such as mTOR. Ironically, this is often misunderstood as a sort of programmed aging. In contrast, aging is a purposeless quasi-program or, figuratively, a shadow of actual programs.
Cell Stress Biology; Roswell Park Cancer Institute; Buffalo, NY USA.
Mikhail V
MV
Blagosklonny
D000375:Aging / Q000235:genetics / Q000502:physiology*; D000818:Animals; D016922:Cellular Senescence / Q000235:genetics; D006128:Growth / Q000235:genetics / Q000502:physiology*; D006801:Humans; D013269:Stochastic Processes; D015003:Yeasts / Q000502:physiology
evolution; geroconversion; gerosuppression; rapalogs; rapamycin; selection; senescence