Differentiation of Functional Groups and Biologically Relevant Anions Using AT-PAMAM Dendrimers.
Biological anions have often proven to be difficult analytes to differentiate in solution. Many of the anions bear similar structural characteristics and similar charge states. Using a commercially available indicator and AT-PAMAM dendrimers, a sensing ensemble for a number of biological anions was constructed. The system was able to identify each of the different analytes as well as the regioisomers of three different tricarboxylates. The system shows responsiveness to not only functional group identity but also the charge state and identity of the anionic species.
Department of Chemistry and Biochemistry, University of Texas at Austin, 1 University Station A1590 Austin, Texas 78751.
S Reid
SR
Long
Marco
M
Bonizzoni
Brenton M
BM
Ray
Eric V
EV
Anslyn
PAMAM dendrimers; anion detection; functional group differentiation; pattern recognition; phosphate