Adapting lung cancer symptom investigation and referral guidelines for general practitioners in Australia: reflections on the utility of the ADAPTE framework.
BACKGROUND
The ADAPTE framework was established to enhance efficiency in guideline development and to facilitate adaptation of high-quality clinical practice guidelines for a local context. It offers guideline developers a systematic methodology for guideline adaptation; however, the feasibility and usability of the process has not been widely evaluated.


OBJECTIVE
A pragmatic approach was undertaken throughout the evaluation of the ADATPE process throughout the development of a guide for general practitioners in Australia regarding the initial investigation of symptoms of lung cancer. At each step of the framework all members of the project team leading the development process reflected on the steps outlined in the ADAPTE. The reflections were collated into a lesson-learned log and analysed following completion of the project.


RESULTS
Several opportunities for improvement were identified to improve usability and practicability of the ADAPTE framework. These items were both specific, in response to using steps and tools, and general issues concerned with the overall ADAPTE framework. Key challenges to using ADAPTE, highlighted in this study, were the lack of clarity about efficiency of the guideline adaptation process, level of assumed knowledge and expertise, and requirement of resources. In response to these challenges, modifications to the ADAPTE have been recommended.


CONCLUSIONS
The ADAPTE framework offers an attractive alternative to de novo guideline synthesis in circumstances where high-quality, compatible guidelines already exist. Pending further evaluation, the modifications identified in this study may be applied to future versions of ADAPTE to improve usability and feasibility of the framework.
Department of General Practice, Monash University, Notting Hill, Victoria, Australia.
Samantha P
SP
Chakraborty
Kay M
KM
Jones
Danielle
D
Mazza
D001315:Australia; D058005:General Practitioners; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D017410:Practice Guidelines as Topic; D012017:Referral and Consultation / Q000458:organization & administration*
ADAPTE; AGREE II; clinical practice; guideline adaptation