Tobacco Mosaic Virus capsid protein as targets for the self-assembly of gold nanoparticles.
Bottom-up self-assembly techniques are a powerful method of building nanoscale structures in an energy efficient and cost effective manner. The use of biological templates, such as proteins, takes advantage of the monodispersity and precision of naturally evolved systems to produce highly organized assemblies of small molecules and nanoparticles. Here we describe a method whereby arginine residues on a viral coat protein (Tobacco Mosaic Virus) are targeted by bis(p-sulfonatophenyl)phenylphosphine (BSPP)-passivated gold nanoparticles with high specificity to create 22 nm rings.
Department of Chemistry, McGill University, Montreal, QC, Canada.
Omar K
OK
Zahr
Amy Szuchmacher
AS
Blum
D036022:Capsid Proteins / Q000737:chemistry* / Q000378:metabolism; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D014027:Tobacco Mosaic Virus / Q000737:chemistry* / Q000378:metabolism; D014771:Virion / Q000737:chemistry / Q000378:metabolism
D036022:Capsid Proteins; D006046:Gold