Erdheim-Chester disease: a rare cause of recurrent fever of unknown origin mimicking lymphoma.
We report the case of a patient with recurrent fever of unknown origin (FUO) with prominent back pain, hepatosplenomegaly, and abdominal/pelvic adenopathy suggesting lymphoma. A bone biopsy showed histiocytic infiltration. Studies for lymphoma were negative, but immunohistochemical stains were diagnostic of Erdheim-Chester disease (ECD). ECD should be included as a rare cause of recurrent FUO with bone involvement.
From the Division of Hematology-Oncology.
Anusiyanthan
A
Mariampillai
Abirami
A
Sivapiragasam
Amit
A
Kumar
Alexander
A
Hindenburg
Burke A
BA
Cunha
Jianhong
J
Zhou
D001706:Biopsy; D001842:Bone and Bones / Q000473:pathology; D003937:Diagnosis, Differential; D031249:Erdheim-Chester Disease / Q000175:diagnosis* / Q000473:pathology; D005335:Fever of Unknown Origin / Q000175:diagnosis* / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology; D008297:Male; D049268:Positron-Emission Tomography; D055815:Young Adult