Ontology-based content analysis of US patent applications from 2001-2010.
Ontology-based semantic text analysis methods allow to automatically extract knowledge relationships and data from text documents. In this review, we have applied these technologies for the systematic analysis of pharmaceutical patents. Hierarchical concepts from the knowledge domains of chemical compounds, diseases and proteins were used to annotate full-text US patent applications that deal with pharmacological activities of chemical compounds and filed in the years 2001-2010. Compounds claimed in these applications have been classified into their respective compound classes to review the distribution of scaffold types or general compound classes such as natural products in a time-dependent manner. Similarly, the target proteins and claimed utility of the compounds have been classified and the most relevant were extracted. The method presented allows the discovery of the main areas of innovation as well as emerging fields of patenting activities - providing a broad statistical basis for competitor analysis and decision-making efforts.
OntoChem GmbH, Heinrich-Damerow-Str. 4, D-06120, Germany.
Lutz
L
Weber
Timo
T
Böhme
Matthias
M
Irmer
D057225:Data Mining / Q000379:methods; D051188:Knowledge Bases; D010330:Patents as Topic; D012660:Semantics; D014481:United States; D018875:Vocabulary, Controlled