Multi-Stencil Streamline Fast Marching: A General 3-D Framework to Determine Myocardial Thickness and Transmurality in Late Enhancement Images.
We propose a fully 3-D methodology for the computation of myocardial nonviable tissue transmurality in contrast enhanced magnetic resonance images. The outcome is a continuous map defined within the myocardium where not only current state-of-the-art measures of transmurality can be calculated, but also information on the location of nonviable tissue is preserved. The computation is done by means of a partial differential equation framework we have called multi-stencil streamline fast marching. Using it, the myocardial and scarred tissue thickness is simultaneously computed. Experimental results show that the proposed 3-D method allows for the computation of transmurality in myocardial regions where current 2-D methods are not able to as conceived, and it also provides more robust and accurate results in situations where the assumptions on which current 2-D methods are based-i.e., there is a visible endocardial contour and its corresponding epicardial points lie on the same slice-, are not met.
Susana
S
Merino-Caviedes
Lucilio
L
Cordero-Grande
Ana
A
Revilla-Orodea
Teresa
T
Sevilla-Ruiz
M Teresa
MT
Pérez
Marcos
M
Martín-Fernández
Carlos
C
Alberola-López
D003287:Contrast Media / Q000008:administration & dosage*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D017682:Myocardial Stunning / Q000473:pathology*; D009206:Myocardium; D009929:Organ Size; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D003287:Contrast Media