A new oleanane-type triterpenoidal saponin from Pulsatilla chinensis.
A new oleanane-type triterpenoidal saponin, 3-O-β-D-glucopyranosyl-hederagenin 23-O-α-D-ribofuranoside (1), was isolated from the roots of Pulsatilla chinensis, and its structure was established on the basis of the spectral data. Compounds 2, 7 and 8 showed moderate cytotoxic activity by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazoliumbromide assay.
a College of Pharmaceutical Science , SooChow University , Suzhou , 215123 , P.R. China.
Zhan
Z
Shu
Zhong
Z
Chen
Yan-li
YL
Liu
Wei-feng
WF
Zhu
Yu-lin
YL
Feng
Qiong-ming
QM
Xu
Xiao-ran
XR
Li
Shi-lin
SL
Yang
D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D031946:Pulsatilla / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization
D012503:Saponins; C413246:oleanane; D009828:Oleanolic Acid