Current status and recommendations for the future of research, teaching, and testing in the biological sciences of radiation oncology: report of the American Society for Radiation Oncology Cancer Biology/Radiation Biology Task Force, executive summary.
In early 2011, a dialogue was initiated within the Board of Directors (BOD) of the American Society for Radiation Oncology (ASTRO) regarding the future of the basic sciences of the specialty, primarily focused on the current state and potential future direction of basic research within radiation oncology. After consideration of the complexity of the issues involved and the precise nature of the undertaking, in August 2011, the BOD empanelled a Cancer Biology/Radiation Biology Task Force (TF). The TF was charged with developing an accurate snapshot of the current state of basic (preclinical) research in radiation oncology from the perspective of relevance to the modern clinical practice of radiation oncology as well as the education of our trainees and attending physicians in the biological sciences. The TF was further charged with making suggestions as to critical areas of biological basic research investigation that might be most likely to maintain and build further the scientific foundation and vitality of radiation oncology as an independent and vibrant medical specialty. It was not within the scope of service of the TF to consider the quality of ongoing research efforts within the broader radiation oncology space, to presume to consider their future potential, or to discourage in any way the investigators committed to areas of interest other than those targeted. The TF charge specifically precluded consideration of research issues related to technology, physics, or clinical investigations. This document represents an Executive Summary of the Task Force report.
21st Century Oncology, LLC, and the American Board of Radiology, Bethesda, Maryland. Electronic address: pwallner@theabr.org.
Paul E
PE
Wallner
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia.
Mitchell S
MS
Anscher
Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Christopher A
CA
Barker
Department of Human Oncology, University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
Michael
M
Bassetti
Departments of Radiation Oncology and Medical Biophysics, Princess Margaret Cancer Center/University of Toronto, Toronto, Ontario, Canada.
Robert G
RG
Bristow
Department of Radiation Oncology, Norton Cancer Center, Louisville, Kentucky.
Yong I
YI
Cha
Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania.
Adam P
AP
Dicker
Department of Radiation Oncology, New York University, New York, New York.
Silvia C
SC
Formenti
Departments of Radiation Oncology and Radiology, Stanford University, Stanford, California.
Edward E
EE
Graves
Department of Radiation Oncology, University of Pennsylvania.
Stephen M
SM
Hahn
Center for Radiation Research, Columbia University, New York, New York.
Tom K
TK
Hei
Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Alec C
AC
Kimmelman
Department of Radiation Oncology, Duke University, Durham, North Carolina.
David G
DG
Kirsch
Department of Human Oncology, University of Wisconsin.
Kevin R
KR
Kozak
Department of Radiation Oncology, University of Michigan.
Theodore S
TS
Lawrence
Department of Radiation Oncology, Oakland University, Oakland, California.
Brian
B
Marples
Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California.
William H
WH
McBride
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia.
Ross B
RB
Mikkelsen
Department of Radiation Oncology, University of California San Francisco, San Francisco, California.
Catherine C
CC
Park
Department of Therapeutic Radiology, Yale University, New Haven, Connecticut.
Joanne B
JB
Weidhaas
Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts.
Anthony L
AL
Zietman
Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California.
Michael
M
Steinberg
D026683:Advisory Committees / Q000458:organization & administration; D001690:Biological Science Disciplines / Q000193:education / Q000592:standards / Q000639:trends; D015415:Biomarkers / Q000032:analysis; D015687:Cell Hypoxia; D003479:Curriculum; D004260:DNA Repair; D005544:Forecasting; D023281:Genomics; D057054:Molecular Imaging; D009369:Neoplasms / Q000378:metabolism / Q000628:therapy; D018787:Radiation Oncology / Q000193:education / Q000592:standards / Q000639:trends; D011837:Radiation-Protective Agents / Q000494:pharmacology; D011838:Radiation-Sensitizing Agents / Q000494:pharmacology; D011853:Radiobiology / Q000193:education / Q000592:standards / Q000639:trends; D012106:Research / Q000193:education / Q000592:standards / Q000639:trends; D012109:Research Support as Topic; D015398:Signal Transduction; D012955:Societies, Medical; D013234:Stem Cells / Q000502:physiology; D057170:Translational Research, Biomedical; D059016:Tumor Microenvironment; D014481:United States
D015415:Biomarkers; D011837:Radiation-Protective Agents; D011838:Radiation-Sensitizing Agents