Consensus Description of Inclusion and Exclusion Criteria for Clinical Studies of Nonallergic Rhinopathy (NAR), Previously Referred to as Vasomotor Rhinitis (VMR), Nonallergic Rhinitis, and/or Idiopathic Rhinitis.
"Nonallergic rhinopathy" was defined by consensus at a Roundtable conference in December 2008 as "a chronic nasal condition with symptoms that may be perennial, persistent, intermittent or seasonal and/or elicited by recognized triggers." The definition includes a well-recognized set of clinical exposures that lead to the symptoms, predominantly congestion, rhinorrhea, and postnasal drip. These clinical characteristics help to identify patients for participation in clinical trials examining the efficacy of treatments for this important disease. The next step is to establish inclusion and exclusion criteria that will provide a framework for the clinical trials. Agreement on study criteria was obtained at the consensus conference by discussion, counterpoint, and compromise.
Institute for Asthma and Allergy, 5454 Wisconsin Ave, Suite 1700, Chevy Chase, MD, Washington, DC. makaliner@aol.com.
Michael A
MA
Kaliner
James N
JN
Baraniuk
Michael S
MS
Benninger
Jonathan A
JA
Bernstein
Phil
P
Lieberman
Eli O
EO
Meltzer
Robert M
RM
Naclerio
Russell A
RA
Settipane
Judith R
JR
Farrar