A novel intermolecular synthesis of γ-lactones via visible-light photoredox catalysis.
Direct γ-lactone formation via visible-light photoredox catalysis has been achieved efficiently including hydroxylalkylation of aromatic alkenes and transesterification. The present photocatalytic protocol has good regioselectivity and substrate compatibility, affording a novel way to intermolecular γ-lactone synthesis by the reaction of styrenes with α-bromo esters in the absence of any external oxidants.
State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou 730000, PR China , and Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry , Chinese Academy of Sciences, Beijing 100190, PR China.
Xiao-Jing
XJ
Wei
Deng-Tao
DT
Yang
Lin
L
Wang
Tao
T
Song
Li-Zhu
LZ
Wu
Qiang
Q
Liu
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D004952:Esters; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D008027:Light; D015394:Molecular Structure; D055668:Photochemical Processes; D013237:Stereoisomerism; D013343:Styrenes / Q000737:chemistry
D000475:Alkenes; D004952:Esters; D006842:Hydrocarbons, Brominated; D007783:Lactones; D013343:Styrenes