Appropriate body mass index and waist circumference cutoffs for categorization of overweight and central adiposity among Uighur adults in Xinjiang.
OBJECTIVE
The current overweight and central adiposity guidelines based on Western populations were not consistent with many studied based on the Asian populations. Uighur people live in Xinjiang Uighur Autonomous Region which is located in the center of Asia. Their overweight and central cutoffs were largely unknown. We aimed to identify cutoffs for body mass index (BMI; in kg/m(2)) and waist circumference (WC; in cm) for categorization of overweight and central adiposity among Uighur adults in Xinjiang.


METHODS
4767 Uighur participants were selected from the Cardiovascular Risk Survey (CRS) which was carried out from October 2007 to March 2010. The age of the participants were from 35 to 101 years old with the mean age of 50.09 years. Anthropometric data, blood pressure, serum concentration of serum total cholesterol, triglyceride, low density lipoprotein (LDL), high density lipoprotein (HDL) and fasting glucose were documented. The prevalence, sensitivity, specificity and distance on the receiver operating characteristic (ROC) curve of each BMI and waist circumference values were calculated.


RESULTS
The prevalence of hypertension, hypercholesterolemia and hypertriglyceridemia were higher with higher BMI for both men and women. The prevalence of hypertension and hypercholesterolemia were higher with higher waist circumference for both men and women. In women, the prevalence of hypertriglyceridemia was noticed to increase as the waist circumference increased. The shortest distance in the receiver operating characteristic curves for hypertension, dyslipidemia, diabetes, or ≥ 2 of these risk factors suggested a BMI cutoff of 26 and a waist circumference cutoff of 90 cm for both men and women.


CONCLUSIONS
Higher cutoffs for BMI and waist circumference are needed in the identification of Uighur patients at high risk of cardiovascular disease.
Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China ; Xinjiang Key Laboratory of Cardiovascular Disease Research, Urumqi, People's Republic of China.
Shuo
S
Pan
Zi-Xiang
ZX
Yu
Yi-Tong
YT
Ma
Fen
F
Liu
Yi-Ning
YN
Yang
Xiang
X
Ma
Zhen-Yan
ZY
Fu
Xiao-Mei
XM
Li
Xiang
X
Xie
You
Y
Chen
Bangdang
B
Chen
Chun-Hui
CH
He
D050154:Adiposity; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000886:Anthropometry; D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005006:Ethnicity; D005215:Fasting; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000150:complications / Q000208:ethnology / Q000473:pathology*; D006973:Hypertension / Q000097:blood / Q000150:complications / Q000208:ethnology / Q000473:pathology*; D015228:Hypertriglyceridemia / Q000097:blood / Q000150:complications / Q000208:ethnology / Q000473:pathology*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D050177:Overweight / Q000097:blood / Q000150:complications / Q000208:ethnology / Q000473:pathology*; D015995:Prevalence; D012372:ROC Curve; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference
D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides