A small cog in a big wheel: PIK3CA mutations in colorectal cancer.
Affiliation of authors: USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (SS, H-JL).
Sebastian
S
Stintzing
Heinz-Josef
HJ
Lenz
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000235:genetics*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D017024:Chemotherapy, Adjuvant; D058534:Class I Phosphatidylinositol 3-Kinases; D002986:Clinical Trials as Topic; D015179:Colorectal Neoplasms / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D000077146:Irinotecan; D002955:Leucovorin / Q000008:administration & dosage; D058990:Molecular Targeted Therapy / Q000379:methods; D009154:Mutation; D009367:Neoplasm Staging; D019869:Phosphatidylinositol 3-Kinases / Q000235:genetics*
D014408:Biomarkers, Tumor; D000077146:Irinotecan; D019869:Phosphatidylinositol 3-Kinases; D058534:Class I Phosphatidylinositol 3-Kinases; C484760:PIK3CA protein, human; D002955:Leucovorin; D005472:Fluorouracil; D002166:Camptothecin