[Role of toll-like receptor 2 in cardiovascular diseases].
Toll-like receptors are the important pattern recognition receptors of innate immune system, which mediate the immunological defence response against pathogen or endogenous damage associated molecules. Recently, more and more researches indicated that Toll-like receptor 2 played vital roles in the pathophysiology of many cardiovascular diseases, including atherosclerosis, coronary diseases, cardiac ischemia-reperfusion injury. In the current report, we review the research progress on the role of Toll-like Receptor 2 in cardiovascular diseases.
Department of Pathology and Pathophysiology, Capital Medical University, Beijing 100069, China.
Lei
L
Wang
Jie
J
Du
Hui-Hua
HH
Li
D050197:Atherosclerosis / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000503:physiopathology*; D006801:Humans; D015427:Reperfusion Injury / Q000503:physiopathology; D051195:Toll-Like Receptor 2 / Q000502:physiology*
C495342:TLR2 protein, human; D051195:Toll-Like Receptor 2