Two-photon-triggered drug delivery in cancer cells using nanoimpellers.
A therapy of cancer cells: Two-photon-triggered camptothecin delivery with nanoimpellers was studied in MCF-7 breast cancer cells. A fluorophore with a high two-photon absorption cross-section was first incorporated in the nanoimpellers. Fluorescence resonance energy transfer (FRET) from the fluorophore to the azobenzene moiety was demonstrated.
Institut Charles Gerhardt Montpellier, UMR-5253 CNRS-UM2-ENSCM-UM1, cc 1701, Place Eugène Bataillon, 34095 Montpellier Cedex 05 (France).
Jonas
J
Croissant
Marie
M
Maynadier
Audrey
A
Gallud
Harmel
H
Peindy N'dongo
Jeff L
JL
Nyalosaso
Gaëlle
G
Derrien
Clarence
C
Charnay
Jean-Olivier
JO
Durand
Laurence
L
Raehm
Françoise
F
Serein-Spirau
Nathalie
N
Cheminet
Thibaut
T
Jarrosson
Olivier
O
Mongin
Mireille
M
Blanchard-Desce
Magali
M
Gary-Bobo
Marcel
M
Garcia
Jie
J
Lu
Fuyuhiko
F
Tamanoi
Derrick
D
Tarn
Tania M
TM
Guardado-Alvarez
Jeffrey I
JI
Zink
D001391:Azo Compounds / Q000737:chemistry*; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D009369:Neoplasms
D001391:Azo Compounds; C009850:azobenzene
azobenzene; cancer; drug delivery; mesoporous materials; two-photon excitation