Radiographically Occult Latent Radiogenic Osteosarcoma Uncovered on Tc-99m Methylene-diphosphonate Bone Scintigraphy.
We present a case of a 70-year-old male who was referred for a technetium-99m methylene-diphosphonate bone scan for mild left hip pain and an elevated alkaline phosphatase level of 770 units/L. No additional information was provided and the patient's history was limited due to a language barrier. We were able to ascertain that the patient had a remote history of prostate cancer, which had been treated with radiation. Originally, we felt the bone scan was compatible with Paget's disease; however, further work-up revealed the presence of osteosarcoma, which was potentially radiation-induced.
Department of Diagnostic Radiology and Molecular Imaging, Oakland University William Beaumont School of Medicine and Health System, Royal Oak, MI, USA.
Prashant
P
Jolepalem
Raymond Y
RY
Yeow
Diane
D
Cosner
John P
JP
Seitz
Bone scan; osteosarcoma; radiogenic malignancy; secondary malignancy