Primary human chorionic gonadotropin secreting germinoma of the corpus callosum.
BACKGROUND
Primary intracranial germinomas are a rare subset of intracranial tumors derived from mis-incorporated germ cells within the folding neural plate during embryogenesis. Though known to arise from midline structures in the central nervous system (CNS), occurrence within the corpus callosum is exceedingly rare.


METHODS
We present a rare case of secreting primary intracranial germinoma with extensive intraventricular metastasis presenting as a multi-cystic butterfly lesion in the genu of the corpus callosum in a young boy.


CONCLUSIONS
Intracranial germ cell tumors must be considered for any multi-cystic lesion arising from midline structures in the CNS in the preadult population.
Department of Medical Oncology, National Cancer Centre, 11 Hospital Drive, Singapore 169610.
Foo Song
FS
Chuan Aaron
Chong Q Q
CQ
Dawn
Chang T E
CT
Kenneth
Ng Wai
NW
Hoe
Soh Shui
SS
Yen
Tham
T
Chee Kian
Corpus callosum; germinoma; intracranial; secreting