[Remineralization of enamel promoted by casein phosphopeptide-amorphous calcium phosphate with different concentration of fluorin].
OBJECTIVE
To evaluate the effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) combined with different concentrations of fluoride on demineralization of enamel remineralization.


METHODS
Extracted premolar teeth for orthodontic reason were immersed into lactic acid gel to prepare artificial white spot lesions. Then the specimens were randomly assigned to 3 groups: 5% CPP-ACP group as control, 5% CPP-ACP +500 mg/L F- group and 5% CPP-ACP +900 mg/L F- group, which were measured by micro-hardness tester. SPSS 18.0 software package was used for data analysis.


RESULTS
There were significant differences in micro-hardness between control group and experimental group 1 and experimental group 2 by SNK-q test (P<0.05).


CONCLUSIONS
CPP-ACP can make the demineralization of enamel remineralization occurs. F can promote the CPP-ACP remineralization. The increase of fluoride can make the CPP-ACP remineralization better below 1000-1500 mg/L.
Department of Orthodontics, Xi'an Jiaotong University. Xi'an 710004, Shaanxi Province, China.E-mail:doctorliulu@126.com.
Lu
L
Liu
Lin
L
Yang
Min
M
Zou
D001641:Bicuspid; D002130:Calcium Phosphates; D002327:Cariostatic Agents; D002364:Caseins; D003743:Dental Enamel; D005459:Fluorides; D006244:Hardness; D006801:Humans; D010710:Phosphates; D010748:Phosphopeptides; D011897:Random Allocation; D014089:Tooth Remineralization
D002130:Calcium Phosphates; D002327:Cariostatic Agents; D002364:Caseins; D010710:Phosphates; D010748:Phosphopeptides; C519480:amorphous calcium phosphate; C447032:casein phosphopeptide-amorphous calcium phosphate nanocomplex; C012980:fluorophosphate; D005459:Fluorides