Ginger for prevention or treatment of drug-induced nausea and vomiting.
OBJECTIVE
In this review, potential benefits of oral ginger for prevention or management of drug- induced nausea and vomiting were evaluated based on the available evidences.


METHODS
By searching medical resources including Scopus, PubMed, Medline, Cochrane central register of controlled trials and Cochrane database systematic reviews, available evidences were collected. Ginger, zingiber, nausea and vomiting were considered as keywords.


CONCLUSIONS
Various studies have evaluated effects of ginger in prevention and management of nausea and vomiting in different conditions such as pregnancy, chemotherapy, and post-operation. Evidences regarding anti-emetic effect of ginger in prevention and treatment of chemotherapy induced nausea and vomiting are limited and results are conflicting. More randomized clinical trials should be conducted to confirm efficacy of ginger in this regards. Ginger showed promising and attractive effects in preventing post-operative nausea and vomiting at least as add-on therapy. The exact role of ginger as anti-emetic in prevention of post- operative nausea and vomiting can be elucidated by future randomized clinical trials.
Fatemeh
F
Dabaghzadeh
Hossein
H
Khalili
Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Enghelab Ave, Tehran, Iran Postal Code: 1417614411, P.O. Box: 14155/6451. khalilih@tums.ac.ir.
Simin
S
Dashti-Khavidaki
D000932:Antiemetics / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects; D020939:Zingiber officinale / Q000737:chemistry*; D006801:Humans; D009325:Nausea / Q000139:chemically induced / Q000188:drug therapy* / Q000517:prevention & control; D028321:Plant Preparations / Q000627:therapeutic use; D020250:Postoperative Nausea and Vomiting / Q000517:prevention & control; D014839:Vomiting / Q000139:chemically induced / Q000188:drug therapy* / Q000517:prevention & control
D000932:Antiemetics; D000970:Antineoplastic Agents; D028321:Plant Preparations