[Anemia and hemoglobin level as prognostic factors of mortality in community-dwelling elderly: evidence from the Bambuí Cohort Study on Aging, Minas Gerais State, Brazil].
The aim of this study was to examine the influence of low hemoglobin (Hb) and anemia on mortality in the elderly in a ten-year follow-up (1997-2007). Among the 1,742 elderly participants in the baseline cohort from Bambuí, Minas Gerais State, Brazil, 1,322 (82.3%) were followed for an average of 8.9 years. Probability of survival was estimated by Kaplan-Meier and Cox's proportional hazard ratios (HR), and confidence intervals (95%CI) were used, considering potential confounders. Anemia and low Hb (lowest tertile) were associated with increased risk of death (HR = 2.63, 95%CI: 1.83-3.76 and HR = 1.38, 95%CI: 1.07-1.79, respectively). The results show that anemia or low Hb (regardless of a diagnosis of anemia) should be interpreted and managed as independent determinants of mortality in this elderly population.
Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brasil.
Clarice Lima Álvares da
CL
Silva
Maria Fernanda
MF
Lima-Costa
Josélia Oliveira Araújo
JO
Firmo
Sérgio Viana
SV
Peixoto
D000368:Aged; D000375:Aging / Q000097:blood; D000740:Anemia / Q000097:blood / Q000401:mortality*; D001938:Brazil / Q000453:epidemiology; D002423:Cause of Death; D015331:Cohort Studies; D005260:Female; D006441:Hemoglobin A / Q000032:analysis*; D006801:Humans; D015994:Incidence; D057187:Independent Living; D053208:Kaplan-Meier Estimate; D008297:Male; D011379:Prognosis; D012959:Socioeconomic Factors
D006441:Hemoglobin A