[The role of dynamic electromyography in the follow-up of chronic immune polyneuropathies].
Nerve conduction studies providing insight into demyelinating process are essential for the diagnostic of chronic inflammatory demyelinating polyradiculoneuropathy. For the diagnostic, several sets of electrophysiologic criteria have been established. To assess the response to treatment, nerve conduction studies are often used in trials and in clinical practice. Nevertheless, the useful of these classical electrophysiologic techniques is debated because of their lack of sensibility and specificity. In the last 20 years, several works have showed that dysfunction of channels and pump of the axonal membrane at the site and around the site of the conduction block can precipitate conduction failure and produce weakness. These important features explaining clinical status are not correctly assessed by conventional nerve conduction studies. New nerve conduction examinations in dynamic conditions can explore these hyperexcitability modifications.
Centre de référence de pathologie neuromusculaire du Grand Sud Ouest, pôle neurosciences, CHU Toulouse-Rangueil, 1, avenue Jean-Poulhes TSA 50032, 31052 Toulouse cedex 09, France. Electronic address: cintas.p@chu-toulouse.fr.
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Cintas
D004576:Electromyography / Q000379:methods; D006801:Humans; D009431:Neural Conduction; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*
Activity-dependent conduction block; Blocs de conduction activité-dépendants; CIDP; Electromyography; Polyneuropathies; Électromyographie