Strategies used by Yersinia enterocolitica to evade killing by the host: thinking beyond Yops.
Yersinia enterocolitica is an important gastrointestinal pathogen. Its pathogenicity has been attributed primarily to the plasmid encoded Yersinia outer proteins or Yops that are known to subvert the immune system. This review, however, highlights the role of Yop-independent mechanisms that help Y. enterocolitica evade immune system and contribute significantly to its survival in the host.
Microbial Pathogenicity Laboratory, Department of Microbiology, University of Delhi South Campus, Benito Juarez Road, New Delhi 110 021, India.
Mahesh Shanker
MS
Dhar
Microbial Pathogenicity Laboratory, Department of Microbiology, University of Delhi South Campus, Benito Juarez Road, New Delhi 110 021, India. Electronic address: virdi_dusc@rediffmail.com.
Jugsharan Singh
JS
Virdi
D001425:Bacterial Outer Membrane Proteins / Q000276:immunology; D054884:Host-Pathogen Interactions; D006801:Humans; D057131:Immune Evasion; D050296:Microbial Viability; D010957:Plasmids; D037521:Virulence Factors / Q000276:immunology*; D015008:Yersinia enterocolitica / Q000276:immunology* / Q000472:pathogenicity*
D001425:Bacterial Outer Membrane Proteins; D037521:Virulence Factors
Immune evasion; Serum resistance; Yersinia enterocolitica