Photoprotection: part I. Photoprotection by naturally occurring, physical, and systemic agents.
The acute and chronic consequences of ultraviolet radiation on human skin are reviewed. An awareness of variations in naturally occurring photoprotective agents and the use of glass, sunglasses, and fabric can lead to effective protection from the deleterious effects of ultraviolet radiation. New systemic agents, including Polypodium leucotomos, afamelanotide, and antioxidants have potential as photoprotective agents.
Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.
Rebecca
R
Jansen
Steven Q
SQ
Wang
Mark
M
Burnett
Uli
U
Osterwalder
Henry W
HW
Lim
D006801:Humans; D011835:Radiation Protection / Q000379:methods*; D014466:Ultraviolet Rays / Q000009:adverse effects*
AO; BCC; IPD; IR; MMP; NMSC; NSAID; PPD; ROS; SCC; SPF; UCA; UPF; UVA; UVB; UVC; UVR; VL; afamelanotide; antioxidant; antioxidants; basal cell carcinoma; glass; immediate pigment darkening; infrared radiation; matrix metalloproteinase; nonmelanoma skin cancer; nonsteroidal antiinflammatory drug; persistent pigment darkening; photoprotection; photoprotective agents; physical systemic photoprotective agents; reactive oxygen species; squamous cell carcinoma; sun protection factor; ultraviolet A light; ultraviolet B light; ultraviolet C light; ultraviolet protection factor; ultraviolet radiation; urocanic acid; visible light; α-MSH; α–melanocyte-stimulating hormone