Immunoenzymatic determination of antibody-bound soluble antigens ofTrypanosoma cruzi.
Anti-Major Cathodic Antigen (MCA) monospecific immunoglobulins ofT. cruzi have been used for the preparation of polyamide-linked immunoadsorbents. A high proportion of serologically positive patients with Chagas disease show the presence of a soluble antigen complexed with human immunoglobulins, which complex binds to those immunoadsorbents as determined by a double sandwich reaction and a peroxidase final determination.
Institut de Technologie des Surfaces Actives, Université de Compiègne, BP. 233, 60206, Compiegne, France.
A
A
Marcipar
S
S
Barnes
E
E
Lentwojt
G
G
Broun