Improvement in gastroesophageal reflux disease symptoms after various bariatric procedures: review of the Bariatric Outcomes Longitudinal Database.
BACKGROUND
The prevalence of gastroesophageal reflux disease (GERD) in the morbidly obese population is as high as 45%. The objective of this study was to compare the efficacy of various bariatric procedures in the improvement of GERD.


METHODS
The Bariatric Outcomes Longitudinal Database is a prospective database of patients who undergo bariatric surgery by a participant in the American Society of Metabolic and Bariatric Surgery Center of Excellence program. GERD is graded on a 6-point scale, from 0 (no history of GERD) to 5 (prior surgery for GERD). Patients with GERD severe enough to require medications (grades 2, 3, and 4) from June 2007 to December 2009 are identified; the resolution of GERD is noted based on 6-month follow-up.


RESULTS
Of a total of 116,136 patients, 36,938 patients had evidence of GERD preoperatively. After excluding patients undergoing concomitant hiatal hernia repair or fundoplication, there were 22,870 patients with 6-month follow-up. Mean age was 47.6±11.1 years, with an 82% female population. Mean BMI was 46.3±8.0 kg/m(2). Mean preoperative GERD score for patients with Roux-en-Y gastric bypass (RYGB) was 2.80±.56, and mean postoperative score was 1.33±1.41 (P<.0001). Similarly, adjustable gastric banding (AGB, 2.77±.57 to 1.63±1.37, P<.0001) and sleeve gastrectomy (SG, 2.82±.57 to 1.85±1.40, P<.0001) had significant improvement in GERD score. GERD score improvement was best in RYGB patients (56.5%; 7955 of 14,078) followed by AGB (46%; 3773 of 8207) and SG patients (41%; 240 of 585).


CONCLUSIONS
All common bariatric procedures improve GERD. Roux-en-Y gastric bypass is superior to adjustable gastric banding and sleeve gastrectomy in improving GERD. Also, the greater the loss in excess weight, the greater the improvement in GERD score.
Department of Surgery, Creighton University Medical Center, Omaha, Nebraska.
Pradeep K
PK
Pallati
Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska.
Abhijit
A
Shaligram
Department of Biostatistics, University of Nebraska Medical Center, Omaha, Nebraska.
Valerie K
VK
Shostrom
Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska.
Dmitry
D
Oleynikov
Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska.
Corrigan L
CL
McBride
Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska. Electronic address: mgoede@unmc.edu.
Matthew R
MR
Goede
D050110:Bariatric Surgery / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D005764:Gastroesophageal Reflux / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009329:Nebraska / Q000453:epidemiology; D009767:Obesity, Morbid / Q000150:complications / Q000601:surgery*; D011184:Postoperative Period; D015995:Prevalence; D012189:Retrospective Studies; D013997:Time Factors; D015431:Weight Loss
Adjustable gastric banding; Bariatric Outcomes Longitudinal Database (BOLD); Gastroesophageal reflux disease (GERD); Roux-en-Y gastric bypass; Sleeve gastrectomy