Tumor ablation: common modalities and general practices.
Tumor ablation is a minimally invasive technique that is commonly used in the treatment of tumors of the liver, kidney, bone, and lung. During tumor ablation, thermal energy is used to heat or cool tissue to cytotoxic levels (less than -40°C or more than 60°C). An additional technique is being developed that targets the permeability of the cell membrane and is ostensibly nonthermal. Within the classification of tumor ablation, there are several modalities used worldwide: radiofrequency, microwave, laser, high-intensity focused ultrasound, cryoablation, and irreversible electroporation. Each technique, although similar in purpose, has specific and optimal indications. This review serves to discuss general principles and technique, reviews each modality, and discusses modality selection.
Department of Radiology, University of Wisconsin Madison, Clinical Sciences Center, Madison, WI. Electronic address: eknavel@uwhealth.org.
Erica M
EM
Knavel
Christopher L
CL
Brace
D055011:Ablation Techniques / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D000818:Animals; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis / Q000601:surgery*; D018579:Patient Selection; D011237:Predictive Value of Tests; D012307:Risk Factors; D025321:Surgery, Computer-Assisted / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D016896:Treatment Outcome
HIFU; IRE; Microwave; cryoablation; laser; radiofrequency