Oral foregut cyst in a neonate.
Oral foregut cysts are congenital choristomas that arise in the oral cavity during embryonic development from remnants of foregut-derived epithelium. This is an unusual report of a neonate with a large congenital sublingual cystic lesion, extending superficially from the left ventral tongue to the anterior floor of the mouth, impeding breast-feeding. The differential diagnosis included dermoid cyst, epidermoid cyst, mucous retention cyst, and oral lymphangioma. The treatment of choice was enucleation under general anesthesia. Histology showed a cystic lesion with a ciliated pseudostratified columnar epithelium with numerous goblet cells. Immunohistochemistry was positive for cytokeratin 7 and thyroid transcription factor 1 and negative for cytokeratin 20, resulting in a final diagnosis of an oral foregut cyst. Three weeks after surgery, the tongue had healed with good mobility, and breast-feeding could be established. No recurrence was present at 6 months of follow-up.
From the *Federal University of Tocantins, Palmas, Tocantins, †São Leopoldo Mandic Institute and Research Center, Campinas, São Paulo; ‡General Public Hospital of Palmas; and §Dona Regina Public Maternity Hospital, Palmas, Tocantins, Brazil.
Ana Cláudia Garcia
AC
Rosa
Daniel Martins
DM
Hiramatsu
Fábio Roberto Ruiz
FR
de Moraes
Fabrício
F
Passador-Santos
Vera Cavalcanti
VC
de Araújo
Andresa Borges
AB
Soares
D002828:Choristoma / Q000473:pathology; D003560:Cysts / Q000473:pathology*; D003937:Diagnosis, Differential; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009062:Mouth Neoplasms / Q000473:pathology*