Current trends in the development of wound dressings, biomaterials and devices.
Wound management covers all aspects of patient care from initial injury, treatment of infection, fluid loss, tissue regeneration, wound closure to final scar formation and remodeling. There are many wound-care products available including simple protective layers, hydrogels, metal ion-impregnated dressings and artificial skin substitutes, which facilitate surface closure. This review examines recent developments in wound dressings, biomaterials and devices. Particular attention is focused on the design and manufacture of hydrogel-based dressings, their polymeric constituents and chemical modification. Finally, topical negative pressure and hyperbaric oxygen therapy are considered. Current wound-management strategies can be expensive, time consuming and labor intensive. Progress in the multidisciplinary arena of wound care will address these issues and be of immense benefit to patients, by improving both clinical outcomes and their quality of life.
Department of Pharmacy, University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, UK.
Claire
C
Martin
Wan Li
WL
Low
Mohd Cairul Iqbal Mohd
MC
Amin
Iza
I
Radecka
Prem
P
Raj
Ken
K
Kenward
D000818:Animals; D001458:Bandages; D001672:Biocompatible Materials; D006801:Humans; D006931:Hyperbaric Oxygenation; D054843:Negative-Pressure Wound Therapy; D017768:Skin, Artificial; D014945:Wound Healing
D001672:Biocompatible Materials