Periocular photodynamic therapy for squamous intra-epidermal carcinoma.
OBJECTIVE
To evaluate the response of Metvix photodynamic therapy (PDT) for the treatment of periocular Bowen's disease.


METHODS
Four patients with biopsy-proven Bowen' disease were treated with Metvix PDT between November 2010 and January 2012. A detailed description of the technique used is described.


RESULTS
All of the patients tolerated the PDT well. All had some clinical response to the treatment, although there was not complete, lasting resolution beyond one year in three out of the four cases.


CONCLUSIONS
PDT can be a good treatment in its own right in selected cases of periocular Bowen's disease.
Department of Dermatology and.
Natasha
N
Casie Chetty
Bridget
B
Hemmant
Anne-Marie
AM
Skellett
D000368:Aged; D000369:Aged, 80 and over; D000622:Aminolevulinic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D001706:Biopsy; D001913:Bowen's Disease / Q000188:drug therapy*; D005123:Eye; D005260:Female; D006801:Humans; D008297:Male; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000008:administration & dosage*; D063465:Skin Cream; D012878:Skin Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
D017319:Photosensitizing Agents; C475457:methyl 5-aminolevulinate; D000622:Aminolevulinic Acid