Acute kidney injury: Short-term statin therapy for prevention of contrast-induced AKI.
Two recent studies suggest that periprocedural statin administration can prevent contrast-induced acute kidney injury in cardiac patients undergoing percutaneous coronary intervention and in renal patients undergoing angiography, with or without intervention. These studies support the routine administration of potent statins before contrast media infusion in these vulnerable patients.
Department of Clinical Biochemistry (Vascular Prevention Clinic), Royal Free Hospital, Royal Free and University College School of Medicine, Pond Street, London NW3 2QG, UK.
Dimitri P
DP
Mikhailidis
Atherosclerosis and Metabolic Syndrome Outpatient Units, Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, 15 Marmara Street, 55132 Thessaloniki, Greece.
Vasilios G
VG
Athyros
D058186:Acute Kidney Injury / Q000139:chemically induced / Q000517:prevention & control*; D003287:Contrast Media / Q000009:adverse effects*; D017023:Coronary Angiography / Q000009:adverse effects* / Q000379:methods; D004334:Drug Administration Schedule; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage*; D013997:Time Factors
D003287:Contrast Media; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors