Thalassemias.
The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the α- or β-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation. This article reviews current diagnostic approaches, complications, and disease management of thalassemia.
Division of Hematology/Oncology, Ann and Robert H. Lurie Children's Hospital of Chicago, 225 East Chicago Avenue, Box #30, Chicago, IL 60611, USA.
Alissa
A
Martin
Alexis A
AA
Thompson
D006801:Humans; D013789:Thalassemia / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D016896:Treatment Outcome
Anemia; Hemoglobinopathies; Iron overload; Thalassemia