Stereoselective formation of amines by nucleophilic addition to azomethine derivatives.
This chapter describes state-of-the-art methods to prepare α-chiral amines by the addition of nonstabilized nucleophiles to imine derivatives. The first part of the chapter illustrates the most effective diastereoselective addition reaction (substrate controlled and chiral auxiliary based methods) whereas the second part focuses on catalytic asymmetric methods.
Andre B
AB
Charette
Vincent
V
Lindsay