Transitions in endocrinology: treatment of Turner's syndrome during transition.
Transition in health care for young patients with Turner's syndrome (TS) should be perceived as a staged but uninterrupted process starting in adolescence and moving into adulthood. As a condition associated with high risk of short stature, cardiovascular diseases, ovarian failure, hearing loss and hypothyroidism, TS requires the attention of a multidisciplinary team. In this review paper, we systematically searched the relevant literature from the last decade to discuss the array of problems faced by TS patients and to outline their optimal management during the time of transfer to adult service. The literature search identified 233 potentially relevant articles of which 114 were analysed. The analysis confirmed that all medical problems present during childhood should also be followed in adult life. Additionally, screening for hypertension, diabetes mellitus, dyslipidaemia, and osteoporosis is needed. After discharge from the paediatric clinic, there is still a long way to go.
Department of Paediatrics, Paediatric Endocrinology and Diabetes, Medical University of Silesia, ul Medykow 16, 40-752 Katowice, Poland.
Aneta
A
Gawlik
Ewa
E
Malecka-Tendera
D000293:Adolescent; D000328:Adult; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000453:epidemiology; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D006311:Hearing Disorders / Q000175:diagnosis / Q000453:epidemiology; D020249:Hormone Replacement Therapy; D006801:Humans; D010024:Osteoporosis / Q000175:diagnosis / Q000453:epidemiology; D011627:Puberty / Q000502:physiology; D060305:Transition to Adult Care; D014424:Turner Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology / Q000628:therapy*