[Endothelial microparticles and erectile dysfunction: an update].
Microparticles are submicron vesicles shed from plasma membranes in response to cell activation, injury and/or apoptosis. Microparticles of various cellular origins, such as platelets, leukocytes, and endothelial cells, are found in the plasma of healthy subjects, and their amount increases under pathological conditions. Recent studies show that endothelial microparticles, a kind of envelope particles derived from endothelial cells, not only constitute a marker of endothelial dysfunction, but also play a major biological role in the diagnostic and therapeutic approaches to erectile dysfunction.
Department of Urology, The Affiliated Hospital of Luzhou Medical College, Luzhou, Sichuan 646000, China. 168794871@qq.com
Yong-Xian
YX
Li
Rui
R
Jiang
Guo-Sheng
GS
Yang
D015415:Biomarkers; D002462:Cell Membrane; D042783:Endothelial Cells / Q000378:metabolism / Q000473:pathology; D007172:Erectile Dysfunction / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008081:Liposomes / Q000378:metabolism*; D008297:Male
D015415:Biomarkers; D008081:Liposomes