[Interest of NT-proBNP in chronic heart failure follow-up].
Reducing readmissions after hospitalisation for acute heart failure is the new challenge of these diseases, approaching 30% within 60 to 90 days of discharge. Congestion related to high ventricular filling pressures, reflected by the high levels of natriuretic peptides, is the main reason for heart failure readmission. Natriuretic peptide levels are a patent prognostic marker of cardiovascular event in chronic heart failure. Treshold values of BNP and NT-proBNP being respectively 125 and 1000 pg/mL. Optimizing treatment of heart failure by monitoring natriuretic peptides, including management of diuretic doses, remains matter of controversies.
Service de cardiologie, Pôle cardio-vasculaire et métabolique, CHU Toulouse-Rangueil, Toulouse, France, Institut de médecine moléculaire de Rangueil, UMR 1048, Université de Toulouse, Toulouse, France, Inserm, UMR 1048, Toulouse, France.
Michel
M
Galinier
Matthieu
M
Berry
Clément
C
Delmas
Pauline
P
Fournier
D002908:Chronic Disease; D003935:Diagnostic Techniques, Cardiovascular; D006333:Heart Failure / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods*; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D011237:Predictive Value of Tests
D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain
NT-proBNP; biomarker; heart failure; prognostic value; therapeutics