[Butyrylcholinesterase activity and cardiovascular risk factors in obese adolescents submitted to an exercise program].
OBJECTIVE
To evaluate the effect of 12 weeks of physical exercise (PE) on cardiovascular risk factors and BChE activity in obese adolescents.


METHODS
The sample consisted of 24 obese adolescents and 51 normal weight controls. The following variables were measured in the initial stage and after 12 weeks: weight, height, BMI, waist circumference (WC), fat percentage (% F), maximal oxygen uptake (VO2max), systolic (SBP) and diastolic (DBP) blood pressure, glucose (GLY) and insulin (INS) at baseline and after 120 min, triacylglycerol (TG), total cholesterol (TC), LDL cholesterol, HDL cholesterol, and BChE activity (kU/l).


RESULTS
After the intervention, there was significant reduction in BMI, WC, %F, TG, GLI 120, INS 120 min, and BChE activity.


CONCLUSIONS
The reduction in BChE activity, observed after physical exercise, was accompanied by the reduction of the variables associated with cardiovascular risk and obesity, indicating that BChE can be used as a secondary marker for the risk associated with early onset obesity.
Gerusa Eisfeld
GE
Milano
Neiva
N
Leite
Thais Januzzi
TJ
Chaves
Gisele Eisfeld
GE
Milano
Ricardo Lehtonen Rodrigues de
RL
Souza
Lupe Furtado
LF
Alle
D000293:Adolescent; D062186:Arterial Pressure / Q000502:physiology; D015992:Body Mass Index; D002091:Butyrylcholinesterase / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000201:enzymology* / Q000503:physiopathology; D016022:Case-Control Studies; D002648:Child; D002784:Cholesterol / Q000097:blood; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D050356:Lipid Metabolism; D008297:Male; D009765:Obesity / Q000201:enzymology* / Q000503:physiopathology; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference
D007328:Insulin; D014280:Triglycerides; D002784:Cholesterol; D002091:Butyrylcholinesterase