A rhodamine-based "turn-on" fluorescent probe for Fe3+ in aqueous solution.
A water-soluble "turn-on" fluorescent probe (RD1) for Fe(3+) based on rhodamine B was designed and synthesized. The fluorescent probe showed "turn-on" fluorescent and colorimetric responses to Fe(3+) with a high selectivity in water containing less than 1% organic cosolvent. Furthermore, bioimaging investigations indicated that the new probe was cell permeable and suitable for monitoring intracellular Fe(3+) in living cells by confocal microscopy with low cytotoxicity.
Department of Chemistry, Anhui University, Hefei 230601, P. R. China. mengxm@ahu.edu.cn.
Shuangzhi
S
Ji
Xiangming
X
Meng
Weipeng
W
Ye
Yan
Y
Feng
Hongting
H
Sheng
Yulei
Y
Cai
Jinsong
J
Liu
Xiaofan
X
Zhu
Qingxiang
Q
Guo
D018360:Crystallography, X-Ray; D005290:Ferric Compounds / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D008280:Magnetics; D008856:Microscopy, Fluorescence; D008958:Models, Molecular; D012235:Rhodamines / Q000737:chemistry*; D012996:Solutions; D013050:Spectrometry, Fluorescence; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013056:Spectrophotometry, Ultraviolet; D014867:Water / Q000737:chemistry
D005290:Ferric Compounds; D005456:Fluorescent Dyes; D012235:Rhodamines; D012996:Solutions; D014867:Water