Inter-STOP symbol distances for the identification of coding regions.
In this study we explore the potential of inter-STOP symbol distances for finding coding regions in DNA sequences. We use the distance between STOP symbols in the DNA sequence and a chi-square statistic to evaluate the nonhomogeneity of the three possible reading frames and the occurrence of one long distance in one of the frames. The results of this exploratory study suggest that inter-STOP symbol distances have strong ability to discriminate coding regions in prokaryotes and simple eukaryotes.
Signal Processing Lab, IEETA and Department of Electronics, Telecommunications and Informatics, University of Aveiro, 3810-193 Aveiro, Portugal.
Carlos A C
CA
Bastos
Vera
V
Afreixo
Sara P
SP
Garcia
Armando J
AJ
Pinho
D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000235:genetics; D017422:Sequence Analysis, DNA
D004247:DNA