A rare synovial sarcoma of the spine in the thoracic vertebral body.
BACKGROUND
Synovial sarcomas of the spine are very rare, most rare of which was occurring in the thoracic vertebral body. The diagnosis of synovial sarcomas was very difficult. It depends on the radiological examination, immunohistochemical examination and gene examination. The best treatment to them was completely surgical resection with negative margins. Other treatments such as radiation therapy and chemotherapy were just adjuvant. The prognosis of synovial sarcomas was disappointing.


METHODS
A 26-year-old male patient had low back pain. The radiological examination showed bony erosion of the T7 vertebral body and no soft tissue mass around the spine. He underwent T7 resection en bloc and internal fixation with two levels above T7 and two levels below T7. Then histopathological and gene examination revealed high malignant synovial sarcoma. So he was treated by chemotherapy and external beam radiation therapy after surgery.


CONCLUSIONS
Primary vertebral body synovial sarcoma is very rare and difficult to diagnose and treat.
Yuanwu
Y
Cao
Chun
C
Jiang
Zixian
Z
Chen
Xiaoxing
X
Jiang
D000328:Adult; D017024:Chemotherapy, Adjuvant; D006801:Humans; D007085:Ilium / Q000637:transplantation; D017116:Low Back Pain / Q000209:etiology; D008297:Male; D010292:Paresthesia / Q000209:etiology; D018714:Radiotherapy, Adjuvant; D035583:Rare Diseases / Q000473:pathology* / Q000628:therapy; D013584:Sarcoma, Synovial / Q000473:pathology* / Q000628:therapy; D013125:Spinal Neoplasms / Q000473:pathology* / Q000628:therapy; D013904:Thoracic Vertebrae / Q000473:pathology*