Action of antialgal compounds fromJuncus effusus L. onSelenastrum capricornutum.
Twenty-nine free and glucosylated dihydrophenanthrenes and tetrahydropyrenes isolated fromJuncus effusus have been tested against the unicellular green algaSelenastrum capricornutum. The free compounds showed a strong inhibitory activity, while the glucosides were inactive or had a slight stimulating effect on growth. Tetrahydropyrene33, obtained by hydrolysis of the naturalβ-glucosides29 and30 or by hemisynthesis from1, is the most active compound, causing 90% inhibition of the growth at 2.5 × 10(-5) M concentration. Synthetic α-glucosides28, 31, and32 showed comparable activity to those of29 and30.
Dipartimento di Chimica Organica & Biologica, Università Federico II, Via Mezzocannone 16, 1-80134, Napoli, Italy.
M D
MD
Greca
A
A
Fiorentino
P
P
Monaco
G
G
Pinto
A
A
Pollio
L
L
Previtera