Presence of hypogammaglobulinemia in patients with severe sepsis, septic shock, and SIRS is associated with increased mortality.
Department of Clinical Biochemistry, Hematology and Immunology, Na Homolce Hospital, 150 30 Prague, Czech Republic. Electronic address: miroslav.prucha@homolka.cz.
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Prucha
Department of Anesthesiology and Intensive Care, First Faculty of Medicine, Charles University in Prague and Thomayer University Hospital, 140 00 Prague, Czech Republic.
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Zazula
Department of Intensive Care Medicine, Klaudian's Hospital, 293 00 Mlada Boleslav, Czech Republic.
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Herold
Institute of Experimental Medicine, Academy of Science, 140 00 Prague, Czech Republic.
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Dostal
Department of Intensive Care Medicine, Na Homolce Hospital, 150 30 Prague, Czech Republic.
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Hyanek
UCL Department of Medicine and NIHR University College London Hospitals, Biomedical Research Centre, UK.
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Bellingan
D000361:Agammaglobulinemia / Q000150:complications / Q000453:epidemiology / Q000401:mortality; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D018805:Sepsis / Q000150:complications / Q000401:mortality; D012772:Shock, Septic / Q000150:complications / Q000401:mortality; D018746:Systemic Inflammatory Response Syndrome / Q000150:complications / Q000401:mortality
D007074:Immunoglobulin G; D007075:Immunoglobulin M