Bilateral juvenile onset primary open-angle glaucoma among keratoconus patients.
OBJECTIVE
To report the occurrence of juvenile open-angle glaucoma (JOAG) in patients with keratoconus.


METHODS
In this observational case series we report 6 eyes of 3 patients with keratoconus who had concomitant JOAG. Corneal topography, intraocular pressure, gonioscopic, and fundus findings were recorded for all the eyes.


RESULTS
All 3 patients presented with corneal ectasia, high intraocular pressure, and advanced glaucomatous damage and had no family history of glaucoma or keratoconus. Two of the 3 patients needed collagen cross-linking with riboflavin for progression of keratoconus and trabeculectomy for control of intraocular pressure. One of the patients also underwent a lamellar keratoplasty for keratoconus.


CONCLUSIONS
This is the first case series pointing toward a possible association of JOAG with keratoconus and highlights the importance of a thorough workup of glaucoma in patients with keratoconus.
Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Sahil
S
Goel
Anita
A
Ganger
Viney
V
Gupta
D003094:Collagen / Q000378:metabolism; D003319:Corneal Stroma / Q000378:metabolism; D019781:Corneal Topography; D003432:Cross-Linking Reagents; D005902:Glaucoma, Open-Angle / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D007640:Keratoconus / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D017319:Photosensitizing Agents / Q000627:therapeutic use; D012256:Riboflavin / Q000627:therapeutic use; D014065:Tonometry, Ocular; D014130:Trabeculectomy; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult
D003432:Cross-Linking Reagents; D017319:Photosensitizing Agents; D003094:Collagen; D012256:Riboflavin