[Fetal cytomegalovirus infection diagnosed on autopsy: a case report].
The cytomegalovirus (CMV) is the most common maternal-fetal transmission infectious disease. The diagnosis of this infection is rarely made on antenatal sonographic signs. Pathological examination could, in this case, make etiologic diagnosis. We report the case of a terminated pregnancy, at the term of 19 weeks of gestation, occurring in a 31-year-old woman. The sonography found a terminated pregnancy with anamnios. Histological examination of samples of fetal internal organs showed intranuclear inclusions, compatible with CMV infection. The main objective of our work is to emphasize the value of histological examination in the diagnosis of fetal death etiology. Moreover, we will discuss the benefit of antenatal screening of CMV maternal infection.
Laboratoire d'anatomie et de cytopathologie pathologiques, hôpital hospitalo-universitaire Habib Bourguiba, 3029 Sfax, Tunisie. Electronic address: malekzribi2004@yahoo.fr.
Malek
M
Zribi
Salwa
S
Makni
Najla
N
Abid
Hela
H
Mnif
Lobna
L
Ayedi
Tahia
T
Boudaouara
D000328:Adult; D001344:Autopsy; D001921:Brain / Q000196:embryology / Q000648:ultrastructure / Q000821:virology; D003586:Cytomegalovirus Infections / Q000150:complications / Q000175:diagnosis / Q000196:embryology* / Q000473:pathology; D005260:Female; D005313:Fetal Death / Q000209:etiology* / Q000473:pathology / Q000821:virology; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure; D008099:Liver / Q000196:embryology / Q000648:ultrastructure / Q000821:virology; D008168:Lung / Q000196:embryology / Q000648:ultrastructure / Q000821:virology; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious
Cytomegalovirus; Cytomégalovirus; Fetal death; Histologie; Histology; Mort fœtale