PSAR-align: improving multiple sequence alignment using probabilistic sampling.
CONCLUSIONS
We developed PSAR-Align, a multiple sequence realignment tool that can refine a given multiple sequence alignment based on suboptimal alignments generated by probabilistic sampling. Our evaluation demonstrated that PSAR-Align is able to improve the results from various multiple sequence alignment tools.


METHODS
The PSAR-Align source code (implemented mainly in C++) is freely available for download at http://bioen-compbio.bioen.illinois.edu/PSAR-Align.
Department of Animal Biotechnology, UBITA Center for Biotechnology Research (CBRU), Konkuk University, Seoul 143-701, Korea, Department of Bioengineering and Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Jaebum
J
Kim
Jian
J
Ma
D000465:Algorithms; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D011336:Probability; D016415:Sequence Alignment; D012984:Software