A simple algorithm to generate firing times for leaky integrate-and-fire neuronal model.
A method to generate first passage times for a class of stochastic processes is proposed. It does not require construction of the trajectories as usually needed in simulation studies, but is based on an integral equation whose unknown quantity is the probability density function of the studied first passage times and on the application of the hazard rate method. The proposed procedure is particularly efficient in the case of the Ornstein-Uhlenbeck process, which is important for modeling spiking neuronal activity.
Dipartimento di Matematica e Applicazioni, Università di Napoli Federico II, Via Cintia, Napoli, Italy. aniello.buonocore@unina.it.
Aniello
A
Buonocore
Luigia
L
Caputo
Enrica
E
Pirozzi
Maria Francesca
MF
Carfora
D000200:Action Potentials / Q000502:physiology*; D000465:Algorithms; D003198:Computer Simulation; D006801:Humans; D008433:Mathematics; D008564:Membrane Potentials / Q000502:physiology*; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*; D011336:Probability; D016016:Proportional Hazards Models; D013269:Stochastic Processes; D013997:Time Factors