In-vivo dark-field and phase-contrast x-ray imaging.
Novel radiography approaches based on the wave nature of x-rays when propagating through matter have a great potential for improved future x-ray diagnostics in the clinics. Here, we present a significant milestone in this imaging method: in-vivo multi-contrast x-ray imaging of a mouse using a compact scanner. Of particular interest is the enhanced contrast in regions related to the respiratory system, indicating a possible application in diagnosis of lung diseases (e.g. emphysema).
1] Physics Department & Institute for Medical Engineering, Technische Universität München, 85748 Garching, Germany [2] Medical Radiation Physics, Lund University, 221 85 Lund, Sweden.
M
M
Bech
A
A
Tapfer
A
A
Velroyen
A
A
Yaroshenko
B
B
Pauwels
J
J
Hostens
P
P
Bruyndonckx
A
A
Sasov
F
F
Pfeiffer
D000818:Animals; D003287:Contrast Media / Q000737:chemistry; D003952:Diagnostic Imaging / Q000379:methods*; D008171:Lung Diseases / Q000175:diagnosis; D051379:Mice; D011859:Radiography; D012137:Respiratory System / Q000000981:diagnostic imaging; D014965:X-Rays
D003287:Contrast Media