Determining enantiomeric composition of disparlure.
A method has been developed to convert disparlure (2-methyl-7,8-epoxyoctadecane) to the correspondingN-(α-methylbenzyl)aziridine with inversion of configuration at both the 7 and 8 positions. The diastereomeric aziridines can be separated on an efficient gas chromatography column, permitting determination of the enantiomeric constitution of the starting disparlure. As little as ca. 0.1% of the minor enantiomer can be detected.
Insect Chemical Ecology Laboratory, USDA, ARS, B-007, BARC-West, 20705-2350, Beltsville, Maryland.
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Oliver
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Waters