One-pot synthesis of 1-azaspiro frameworks initiated by photooxidation of simple furans.
A range of 1-azaspirocycles, spiroaminals and 1,6-diazaspirocycles has been synthesized, starting from simple and readily accessible furan precursors, using a cascade reaction sequence initiated by singlet oxygen.
Department of Chemistry, University of Crete, 71003 Iraklion, Crete, Greece. vasil@chemistry.uoc.gr.
Dimitris
D
Kalaitzakis
Eirini
E
Antonatou
Georgios
G
Vassilikogiannakis
D001372:Aza Compounds / Q000737:chemistry*; D003500:Cyclization; D005663:Furans / Q000737:chemistry*; D008027:Light; D010084:Oxidation-Reduction; D026082:Singlet Oxygen / Q000737:chemistry; D013141:Spiro Compounds / Q000138:chemical synthesis / Q000737:chemistry*
D001372:Aza Compounds; D005663:Furans; D013141:Spiro Compounds; D026082:Singlet Oxygen; C039281:furan