Miliary tuberculosis with indeterminate interferon gamma release assay results.
Recently, interferon gamma release assays (IGRAs) have become an important clinical tool for detecting latent tuberculosis. However, IGRA results may impede making a diagnosis. We herein present an interesting case of miliary tuberculosis with a nonspecific IGRA reaction due to hemophagocytosis.
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan.
Takahito
T
Nei
Yousuke
Y
Fujisawa
Yuuki
Y
Izumi
Akito
A
Tetsuka
Yosie
Y
Arita
Hiroshige
H
Murata
Keisuke
K
Sawai
Mitsunobu
M
Kitamura
Hideki
H
Miyachi
Yusuke
Y
Hosokawa
Koichi
K
Akutsu
Takeshi
T
Yamamoto
Keiji
K
Tanaka
Akihiro
A
Shinoyama
D000942:Antigens, Bacterial / Q000008:administration & dosage; D005188:False Negative Reactions; D017809:Fatal Outcome; D006801:Humans; D007371:Interferon-gamma / Q000096:biosynthesis*; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000276:immunology; D010587:Phagocytosis; D013601:T-Lymphocytes / Q000276:immunology; D014391:Tuberculosis, Miliary / Q000175:diagnosis* / Q000276:immunology*
D000942:Antigens, Bacterial; D007371:Interferon-gamma