Comparing cyanoacrylate tissue adhesive and conventional subcuticular skin sutures for maxillofacial incisions--a prospective randomized trial considering closure time, wound morbidity, and cosmetic outcome.
OBJECTIVE
To compare octyl-2-cyanoacrylate (2-OCA) tissue adhesive with subcuticular suture for the closure of incisions in the maxillofacial region to determine 1) whether it is faster than traditional subcuticular suturing, 2) whether the number and length of incisions affect closure time, 3) wound morbidity, 4) patient satisfaction outcome, and 5) cosmetic outcome.


METHODS
In a prospective randomized clinical trial, 29 patients were allocated to 1 of 2 groups for the closure of skin incisions using 2-OCA or conventional subcuticular skin sutures. Postoperative follow-up evaluated wound healing at 5 to 10 days and at 3 months. Assessment of cosmetic outcome was performed by a plastic surgeon using a modified Hollander Wound Evaluation Scale and a validated visual analog scale. Comparisons between groups were performed using the Student t test and χ(2) test.


RESULTS
Twenty incisions in 14 patients were closed with 2-OCA and 20 incisions in 15 patients were closed with subcuticular sutures. Mean time of closure was significantly (P < .005) faster with 2-OCA at 69.50 ± 33.39 seconds compared with 379.00 ± 75.39 seconds in the suture group. There was no significant difference in wound complications between the 2 groups; also, there was no significant difference in patient satisfaction and cosmetic outcome of scars at the 3-month follow-up between the 2 groups.


CONCLUSIONS
2-OCA tissue adhesive is an excellent alternative to sutures for effective, reliable, and faster skin closure of maxillofacial incisions.
Lecturer, Department of Oral and Maxillofacial Surgery, Himachal Pradesh Government Dental College and Hospital, Shimla, Himachal Pradesh, India. Electronic address: dr.abhisheksoni@gmail.com.
Abhishek
A
Soni
Ravi
R
Narula
Anil
A
Kumar
Monika
M
Parmar
Manish
M
Sahore
Mohinder
M
Chandel
D000328:Adult; D003487:Cyanoacrylates; D062109:Dermatologic Surgical Procedures / Q000379:methods*; D004955:Esthetics, Dental; D005145:Face / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D019647:Oral Surgical Procedures / Q000379:methods*; D017060:Patient Satisfaction; D011183:Postoperative Complications; D011446:Prospective Studies; D016037:Single-Blind Method; D013536:Suture Techniques; D013997:Time Factors; D014014:Tissue Adhesives; D016896:Treatment Outcome; D058106:Wound Closure Techniques; D014945:Wound Healing; D055815:Young Adult
D003487:Cyanoacrylates; D014014:Tissue Adhesives