Study of a centrifugal blood pump in a mock loop system.
An implantable centrifugal blood pump (ICBP) is being developed to be used as a ventricular assist device (VAD) in patients with severe cardiovascular diseases. The ICBP system is composed of a centrifugal pump, a motor, a controller, and a power supply. The electricity source provides power to the controller and to a motor that moves the pump's rotor through magnetic coupling. The centrifugal pump is composed of four parts: external conical house, external base, impeller, and impeller base. The rotor is supported by a pivot bearing system, and its impeller base is responsible for sheltering four permanent magnets. A hybrid cardiovascular simulator (HCS) was used to evaluate the ICBP's performance. A heart failure (HF) (when the heart increases beat frequency to compensate for decrease in blood flow) was simulated in the HCS. The main objective of this work is to analyze changes in physiological parameters such as cardiac output, blood pressure, and heart rate in three situations: healthy heart, HF, and HF with left circulatory assistance by ICBP. The results showed that parameters such as aortic pressure and cardiac output affected by the HF situation returned to normal values when the ICBP was connected to the HCS. In conclusion, the test results showed satisfactory performance for the ICBP as a VAD.
Dante Pazzanese Institute of Cardiology, São Paulo, São Paulo, Brazil.
Beatriz
B
Uebelhart
Bruno Utiyama
BU
da Silva
Jeison
J
Fonseca
Eduardo
E
Bock
Juliana
J
Leme
Cibele
C
da Silva
Tarcísio
T
Leão
Aron
A
Andrade
D001243:Assisted Circulation; D006321:Heart / Q000502:physiology* / Q000503:physiopathology*; D006333:Heart Failure / Q000503:physiopathology / Q000601:surgery*; D006339:Heart Rate; D006353:Heart-Assist Devices; D006801:Humans; D008955:Models, Cardiovascular; D011474:Prosthesis Design
Cardiovascular simulator; Centrifugal blood pump; Ventricular assist device