Acquired aplastic anemia in children.
This article provides a practice-based and concise review of the etiology, diagnosis, and management of acquired aplastic anemia in children. Bone marrow transplantation, immunosuppressive therapy, and supportive care are discussed in detail. The aim is to provide the clinician with a better understanding of the disease and to offer guidelines for the management of children with this uncommon yet serious disorder.
Division of Hematology, Department of Pediatrics, Comprehensive Bone Marrow Failure Center, The Children's Hospital of Philadelphia, 3615 Civic Center Boulevard, ARC 302, Philadelphia, PA 19104, USA.
Helge D
HD
Hartung
Timothy S
TS
Olson
Monica
M
Bessler
D000741:Anemia, Aplastic / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D016026:Bone Marrow Transplantation; D002648:Child; D006801:Humans; D007166:Immunosuppressive Agents; D015996:Survival Rate; D016896:Treatment Outcome
D007166:Immunosuppressive Agents
Acquired aplastic anemia; Bone marrow failure; Bone marrow transplant for severe aplastic anemia in children; Immune-mediated aplastic anemia; Immunosuppressive therapy for severe aplastic anemia in children