Rat jugular catheter model of biofilm-mediated infection.
Staphylococcus epidermidis is now recognized as the primary cause of nosocomial catheter-mediated infections. Bacteria may be introduced exogenously via contamination of the catheter hub or insertion site and endogenously from sepsis. The in vivo model described in this chapter examines the infection resulting from hematogenous seeding of jugular vein catheters.
Department of Pathology and Microbiology, Center for Staphylococcal Research, University of Nebraska Medical Center, Omaha, NE, USA.
Carolyn R
CR
Schaeffer
Keith M
KM
Woods
G Matthew
GM
Longo
D000818:Animals; D018441:Biofilms; D055499:Catheter-Related Infections / Q000382:microbiology*; D002405:Catheterization, Central Venous; D002408:Catheters, Indwelling / Q000382:microbiology*; D004195:Disease Models, Animal; D006801:Humans; D007601:Jugular Veins / Q000382:microbiology; D051381:Rats; D013203:Staphylococcal Infections / Q000382:microbiology*; D013212:Staphylococcus epidermidis / Q000502:physiology*