Intraoperative sub-tenon injection increases optic nerve length transection during enucleation.
OBJECTIVE
To determine the effect of sub-Tenon injection on the length of optic nerve resected during enucleation.


METHODS
Case-control laboratory study on 22 orbits of 11 unpreserved, fresh-frozen human cadavers. Each cadaver underwent a conventional enucleation technique on one side and an otherwise identical technique on the contralateral side that included sub-Tenon injection of 2.5 ml normal saline in each oblique quadrant. Resected optic nerve lengths were measured and compared using Student t tests.


RESULTS
The mean optic nerve length was 15.2 mm (range, 5.0-21.0 mm) in the sub-Tenon injection group and 11.3 mm (range, 5.0-19.0 mm) in control group (p = 0.015).


CONCLUSIONS
Sub-Tenon injection during enucleation allows for significantly longer optic nerve resection lengths in unpreserved, fresh-frozen human cadavers.
*Department of Ophthalmology, Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; †Department of Ophthalmology, Cole Eye Institute; and ‡Department of Anatomy, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, U.S.A.
Natta
N
Sakolsatayadorn
Bryan R
BR
Costin
Stephen A
SA
McNutt
Tal J
TJ
Rubinstien
Jennifer M
JM
McBride
Julian D
JD
Perry
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002102:Cadaver; D016022:Case-Control Studies; D015353:Eye Enucleation / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D007267:Injections / Q000379:methods; D007430:Intraoperative Care / Q000379:methods; D008297:Male; D008875:Middle Aged; D009366:Neoplasm Seeding; D009900:Optic Nerve / Q000187:drug effects / Q000601:surgery*; D011897:Random Allocation
D000779:Anesthetics, Local