Reproductive issues in adults with cystic fibrosis: Implications for genetic counseling.
This article reviews reproductive issues faced by the growing number of individuals with cystic fibrosis (CF) who reach adulthood. Approximately 97-98% of males with CF are infertile and they may have an increased risk for genitourinary anomalies. Females with CF may experience delayed puberty, irregular menstrual cycles, and decreased fertility. Women with CF who have good clinical scores, good nutritional status, and normal lung volumes with mild to moderate airway obstruction, have a better chance for successful pregnancies. The role of the genetic counselor in counseling adults with CF is discussed and resources for CF adults are provided.
Department of Obstetrics and Gynecology, The University of Chicago, 5841 S. Maryland Avenue, MC2050, 60637, Chicago, Illinois.
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Lemke