Ulcerating type 1 lepra reaction mimicking lazarine leprosy: an unusual presentation of immune reconstitution inflammatory syndrome in an HIV-infected patient.
Leprosy maybe "unmasked" in the context of immune reconstitution inflammatory syndrome and treating dermatologists, particularly in highly endemic areas for Hansen's disease, need to be cognizant to this possibility. It may also reflect emergence of a previously clinically silent infection in the course of immunologic restoration.
Fr Muller Medical College, Dermatology & Venereology, Mangalore, India.
Ramesh
R
Bhat
Malcolm
M
Pinto
Sukumar
S
Dandakeri
Srinath
S
Kambil
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000382:microbiology; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D003937:Diagnosis, Differential; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D015439:Leprosy, Borderline / Q000139:chemically induced* / Q000175:diagnosis; D015441:Leprosy, Tuberculoid / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D009166:Mycobacterium leprae / Q000302:isolation & purification; D011239:Prednisolone / Q000627:therapeutic use; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D011239:Prednisolone
AIDS; HIV; Human immunodeficiency virus; IRIS; Mycobacterium leprae; antiretroviral therapy; corticosteroids; immune reconstitution inflammatory syndrome; leprosy; treatment; type 1 lepra reaction