High-sensitive and broad-dynamic-range quantitative phase imaging with spectral domain phase microscopy.
Spectral domain phase microscopy for high-sensitive and broad-dynamic-range quantitative phase imaging is presented. The phase retrieval is realized in the depth domain to maintain a high sensitivity, while the phase information obtained in the spectral domain is exploited to extend the dynamic range of optical path difference. Sensitivity advantage of phase retrieved in the depth domain over that in the spectral domain is thoroughly investigated. The performance of the proposed depth domain phase based approach is illustrated by phase imaging of a resolution target and an onion skin.
Yangzhi
Y
Yan
Zhihua
Z
Ding
Yi
Y
Shen
Zhiyan
Z
Chen
Chen
C
Zhao
Yang
Y
Ni
D000465:Algorithms; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007089:Image Enhancement / Q000295:instrumentation* / Q000379:methods*; D008858:Microscopy, Phase-Contrast / Q000295:instrumentation* / Q000379:methods*; D008954:Models, Biological; D019697:Onions / Q000166:cytology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity