Impact of different catheter lock strategies on bacterial colonization of permanent central venous hemodialysis catheters.
Thirty-nine hemodialysis patients with permanent central venous catheters were analyzed for bacterial catheter colonization comparing different catheter-lock strategies. The closed needleless Tego connector with sodium chloride lock solution was significantly more frequently colonized with bacteria than the standard catheter caps with antimicrobially active citrate lock solution (odds ratio, 0.22 [95% confidence interval, 0.07-0.71]; P = .011).
Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Basel, Switzerland.
Stefan
S
Erb
Andreas F
AF
Widmer
Sarah
S
Tschudin-Sutter
Ursula
U
Neff
Manuela
M
Fischer
Michael
M
Dickenmann
Philipp
P
Grosse
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000494:pharmacology; D055499:Catheter-Related Infections / Q000209:etiology / Q000517:prevention & control; D002408:Catheters, Indwelling / Q000382:microbiology*; D062905:Central Venous Catheters / Q000382:microbiology*; D019343:Citric Acid / Q000494:pharmacology*; D015169:Colony Count, Microbial; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000295:instrumentation*; D012965:Sodium Chloride / Q000494:pharmacology*
D000925:Anticoagulants; D019343:Citric Acid; D012965:Sodium Chloride