First successful use of leukocyte apheresis as maintenance therapy for Crohn's disease in the United Kingdom.
We describe the case of a 24 year old male with severe fistulating Crohn's disease who failed mutliple modalities of medical and surgical therapy. We present objective and subjective evidence of disease remission after induction and maintenance treatment with leukocyte apheresis. This is the first described case of successful maintenance treatment of severe Crohn's disease with leukocyte apheresis in the United Kingdom.
Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation Trust, United Kingdom.
David
D
Tate
Vida
V
Cairnes
Roland
R
Valori
Richard
R
Makins
D002097:C-Reactive Protein / Q000378:metabolism; D003424:Crohn Disease / Q000097:blood / Q000628:therapy*; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007937:Leukapheresis / Q000379:methods*; D008297:Male; D010976:Platelet Count; D012074:Remission Induction; D055502:Secondary Prevention; D012709:Serum Albumin / Q000378:metabolism; D006113:United Kingdom; D055815:Young Adult
D006454:Hemoglobins; D012709:Serum Albumin; D002097:C-Reactive Protein
Crohn's disease