NPInter v2.0: an updated database of ncRNA interactions.
NPInter (http://www.bioinfo.org/NPInter) is a database that integrates experimentally verified functional interactions between noncoding RNAs (excluding tRNAs and rRNAs) and other biomolecules (proteins, RNAs and genomic DNAs). Extensive studies on ncRNA interactions have shown that ncRNAs could act as part of enzymatic or structural complexes, gene regulators or other functional elements. With the development of high-throughput biotechnology, such as cross-linking immunoprecipitation and high-throughput sequencing (CLIP-seq), the number of known ncRNA interactions, especially those formed by protein binding, has grown rapidly in recent years. In this work, we updated NPInter to version 2.0 by collecting ncRNA interactions from recent literature and related databases, expanding the number of entries to 201 107 covering 18 species. In addition, NPInter v2.0 incorporated a service for the BLAST alignment search as well as visualization of interactions.
Laboratory of Noncoding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China, University of Chinese Academy of Sciences, Beijing 100049, China and Bioinformatics Research Group, Advanced Computing Research Laboratory, Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100190, China.
Jiao
J
Yuan
Wei
W
Wu
Chaoyong
C
Xie
Guoguang
G
Zhao
Yi
Y
Zhao
Runsheng
R
Chen
D003196:Computer Graphics; D004247:DNA / Q000378:metabolism; D030561:Databases, Nucleic Acid; D020407:Internet; D011506:Proteins / Q000378:metabolism; D012313:RNA / Q000378:metabolism; D022661:RNA, Untranslated / Q000378:metabolism*
D011506:Proteins; D022661:RNA, Untranslated; D012313:RNA; D004247:DNA