Feasibility of using auto Mod-MPI system, a novel technique for automated measurement of fetal modified myocardial performance index.
OBJECTIVE
To evaluate the reproducibility of measurement of the fetal left modified myocardial performance index (Mod-MPI) determined using a novel automated system.


METHODS
This was a prospective study of 116 ultrasound examinations from 110 normal singleton pregnancies at 12 + 1 to 37 + 1 weeks' gestation. Two experienced operators each measured the left Mod-MPI twice manually and twice automatically using the Auto Mod-MPI system. Intra- and interoperator reproducibility were assessed using intraclass correlation coefficients (ICCs) and the manual and automated measurements obtained by the more experienced operator were compared using Bland-Altman plots and ICCs.


RESULTS
Both operators successfully measured the left Mod-MPI in all cases using the Auto Mod-MPI system. For both operators, intraoperator reproducibility was higher when performing automated measurements (ICC = 0.967 and 0.962 for Operators 1 and 2, respectively) than when performing manual measurements (ICC = 0.857 and 0.856 for Operators 1 and 2, respectively). Interoperator agreement was also better for automated than for manual measurements (ICC = 0.930 vs 0.723, respectively). There was good agreement between the automated and manual values measured by the more experienced operator.


CONCLUSIONS
The Auto Mod-MPI system is a reliable technique for measuring fetal left Mod-MPI and demonstrates excellent reproducibility.
Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
M-Y
MY
Lee
H-S
HS
Won
E-J
EJ
Jeon
H C
HC
Yoon
J Y
JY
Choi
S J
SJ
Hong
M-J
MJ
Kim
D001331:Automation; D003430:Cross-Sectional Studies; D015150:Echocardiography, Doppler; D005240:Feasibility Studies; D005260:Female; D005318:Fetal Heart / Q000000981:diagnostic imaging / Q000502:physiology*; D006801:Humans; D015588:Observer Variation; D011247:Pregnancy; D011446:Prospective Studies; D015203:Reproducibility of Results; D016216:Ultrasonography, Prenatal / Q000379:methods / Q000592:standards
Tei index; fetal cardiac function; fetal echocardiography; fetal left ventricular function; modified myocardial performance index