Low intensity aerobic exercise and oxidative stress markers in older adults.
This comparative study examined the effects of regular low intensity aerobic exercise on oxidative stress markers in older adults. The study was carried out on 15 sedentary subjects (age: 65.1 ± 3.5 years) versus 18 subjects performing fitness exercises (age: 65.8 ± 3.3 years). Before and after an incremental exercise test, oxidative stress markers were assessed. Superoxide dismutase was higher at rest and at the recovery for the physically active subjects compared with sedentary subjects (p < .05). At recovery, glutathione peroxidase and α -Tocopherol increased significantly above the resting values only in the active group (p < .05). Malondialdehyde had increased in both groups (p < .01), associated with a higher level in the sedentary group (p < .05) at the recovery. These data suggest that low intensity aerobic exercise may be useful to prevent the decline of antioxidants linked with aging.
Université Lille Nord de France, UDSL, EA-4488 Activité Physique Muscle Santé, Faculté des Sciences du Sport, France.
Mohamed A
MA
Bouzid
Omar
O
Hammouda
Régis
R
Matran
Sophie
S
Robin
Claudine
C
Fabre
D000368:Aged; D000375:Aging / Q000502:physiology*; D000975:Antioxidants / Q000378:metabolism*; D015415:Biomarkers / Q000097:blood; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test / Q000379:methods; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D018384:Oxidative Stress / Q000502:physiology*; D010809:Physical Fitness / Q000502:physiology; D057185:Sedentary Behavior; D013482:Superoxide Dismutase / Q000097:blood; D024502:alpha-Tocopherol / Q000097:blood
D000975:Antioxidants; D015415:Biomarkers; D008315:Malondialdehyde; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D024502:alpha-Tocopherol