Automatic analysis of selected choroidal diseases in OCT images of the eye fundus.
BACKGROUND
This paper describes a method for automatic analysis of the choroid in OCT images of the eye fundus in ophthalmology. The problem of vascular lesions occurs e.g. in a large population of patients having diabetes or macular degeneration. Their correct diagnosis and quantitative assessment of the treatment progress are a critical part of the eye fundus diagnosis.


METHODS
The study analysed about 1'000 OCT images acquired using SOCT Copernicus (Optopol Tech. SA, Zawiercie, Poland). The proposed algorithm for image analysis enabled to analyse the texture of the choroid portion located beneath the RPE (Retinal Pigment Epithelium) layer. The analysis was performed using the profiled algorithm based on morphological analysis and texture analysis and a classifier in the form of decision trees.


RESULTS
The location of the centres of gravity of individual objects present in the image beneath the RPE layer proved to be important in the evaluation of different types of images. In addition, the value of the standard deviation and the number of objects in a scene were equally important. These features enabled classification of three different forms of the choroid that were related to retinal pathology: diabetic edema (the classification gave accuracy ACC1 = 0.73), ischemia of the inner retinal layers (ACC2 = 0.83) and scarring fibro vascular tissue (ACC3 = 0.69). For the cut decision tree the results were as follows: ACC1 = 0.76, ACC2 = 0.81, ACC3 = 0.68.


CONCLUSIONS
The created decision tree enabled to obtain satisfactory results of the classification of three types of choroidal imaging. In addition, it was shown that for the assumed characteristics and the developed classifier, the location of B-scan does not significantly affect the results. The image analysis method for texture analysis presented in the paper confirmed its usefulness in choroid imaging. Currently the application is further studied in the Clinical Department of Ophthalmology in the District Railway Hospital in Katowice, Medical University of Silesia, Poland.
Department of Biomedical Computer Systems, University of Silesia, Faculty of Computer Science and Materials Science, Institute of Computer Science, ul, Będzińska 39, Sosnowiec 41-200, Poland. koprow@us.edu.pl.
Robert
R
Koprowski
Slawomir
S
Teper
Zygmunt
Z
Wróbel
Edward
E
Wylegala
D000293:Adolescent; D000328:Adult; D000368:Aged; D000465:Algorithms; D001331:Automation; D002648:Child; D015862:Choroid Diseases / Q000175:diagnosis*; D005654:Fundus Oculi; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008875:Middle Aged; D041623:Tomography, Optical Coherence / Q000379:methods*; D055815:Young Adult