Post-injection sciatic neuropathy in a cynomolgus macaque (Macaca fascicularis).
BACKGROUND
Intramuscular injection is a common route parenteral used in primates.


METHODS
A cynomolgus macaque was evaluated for acute lameness and atrophy of the left leg with no evidence of trauma.


RESULTS
History revealed ketamine injection 12 days prior.


CONCLUSIONS
Histologic examination supported traumatic injection neuropathy due to intramuscular injection.
Veterinary Services, Nonclinical Safety Assessment at Covance Laboratories, Inc., Chandler, Arizona, USA.
C A
CA
Carrier
K B
KB
Donnelly
D000778:Anesthetics, Dissociative / Q000009:adverse effects*; D000818:Animals; D018420:Ape Diseases / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D007273:Injections, Intramuscular / Q000009:adverse effects / Q000662:veterinary; D007649:Ketamine / Q000009:adverse effects*; D007794:Lameness, Animal / Q000175:diagnosis* / Q000209:etiology; D008252:Macaca fascicularis; D020426:Sciatic Neuropathy / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*
D000778:Anesthetics, Dissociative; D007649:Ketamine
intramuscular injection; ketamine; monkey; nerve; non-human primate