Superoxide disproportionation driven by zinc complexes with various steric and electrostatic properties.
Attractive models: Synthetic Zn(II) complexes were investigated as models of copper-zinc superoxide dismutase. Superoxide underwent a unique disproportionation reaction in the electrostatic sphere of the complexes (see picture; bpy=2,2'-bipyridyl). The effectiveness of the Zn(II) complexes in inducing the disproportionation of superoxide depended on both the Lewis acidity and the coordination geometry of the Zn center.
Department of Life and Materials Engineering, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555 (Japan); RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan).
Akira
A
Wada
Koichiro
K
Jitsukawa
Hideki
H
Masuda
D001672:Biocompatible Materials / Q000737:chemistry* / Q000378:metabolism; D002384:Catalysis; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry*; D003300:Copper / Q000737:chemistry; D055664:Electrochemical Techniques; D055672:Static Electricity; D013482:Superoxide Dismutase / Q000737:chemistry / Q000378:metabolism; D013481:Superoxides / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
D001672:Biocompatible Materials; D056831:Coordination Complexes; D013481:Superoxides; D003300:Copper; D013482:Superoxide Dismutase; D015032:Zinc
disproportionation; enzyme models; peroxide; superoxide; zinc complexes