Structures and allelopathic effects ofNuphar alkaloids: Nupharolutine and 6,6'-dihydroxythiobinupharidine.
Two of the majorNuphar alkaloids, nupharolutine and 6,6'-dihydroxythiobinupharidine, were isolated from the aquatic perennial herbNuphar lutea (L.) Sibth. & Sm., yellow water lily. In a lettuce seedling bioassay of the two pure compounds, the former was inactive and the latter was highly inhibitory of radicle elongation at concentrations greater than 2 ppm. Structures and stereochemistry of the two compounds were confirmed by DEPT,(1)H-(1)H COSY,(1)H-(13)C COSY, and(1)H-(1)H NOESY experiments.
Department of Chemistry and Biochemistry, University of Southern Mississippi, 39406-5043, Hattiesburg, Mississippi.
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Elakovich
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Yang