[Acute risk assessment of cumulative dietary exposure to organophosphorus pesticide among people in Jiangsu province].
OBJECTIVE
To understand the cumulative dietary exposure of Jiangsu residents to organophosphorus (OPs) pesticide and make acute risk assessment.


METHODS
Integrated the data of the nutrition and health status of residents in Jiangsu and the data of monitoring of OPs pesticide in agricultural products. Chlorpyrifos was selected as index compound (index chemical, IC), then use relative potency factor (RPF) approach which commended by EPA and simple distribution evaluation. Caloulated the dietary cumulative exposure of OPs pesticide among Jiangsu residents and compared with acute reference dose (ARfD), then made risk assessment.


RESULTS
The exposure of rural group of age 3-6 and 7-11 were 133.84 microg/kg BW and 154.32 microg/kg BW, exceeded ARfD. The exposure level of kids and elder was higher than adults. The exposure level of rural residents were higher than urban residents. The highest contribution to the food of each age group was greengrocery and leek.


CONCLUSIONS
The average level of exposure was safety in Jiangsu, high exposure children were at acute poisoning risk. High contribution food such as greengrocery and leek should be strengthen monitoring.
The Key Laboratory of Medical Engineering Environment/Nutrition and Food Hygiene Department, School of Public Health, Southeast University, Nanjing 210009, China.
Minxian
M
Zhao
Cannan
C
Wang
Tingting
T
Li
Nannan
N
Yi
Xiansong
X
He
Hui
H
Wu
Xinya
X
Yao
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002681:China; D004032:Diet / Q000706:statistics & numerical data*; D004781:Environmental Exposure / Q000009:adverse effects / Q000032:analysis*; D005260:Female; D005504:Food Analysis; D005506:Food Contamination / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009943:Organophosphorus Compounds / Q000032:analysis*; D010573:Pesticide Residues / Q000032:analysis*; D018570:Risk Assessment; D055815:Young Adult
D009943:Organophosphorus Compounds; D010573:Pesticide Residues