Polysaccharides in Lentinus edodes: isolation, structure, immunomodulating activity and future prospective.
Lentinus edodes has been valued as edible and medical resources. Polysaccharides have been known to be the most potent antitumor and immunomodulating substance in Lentinus edodes. In this review, we summarize the current knowledge of the polysaccharides isolated from Lentinus edodes, including extraction and purification methods, chemical structure and chain conformation, the effects on innate and adaptive immunity and their mechanism, relationship between structure and function, and the future prospects.
a College of Light Industry and Food Sciences, South China University of Technology , 381 Wushan Road , Guangzhou , 510640 , China.
Xiaofei
X
Xu
Huidan
H
Yan
Jian
J
Tang
Jian
J
Chen
Xuewu
X
Zhang
D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D056747:Immunomodulation / Q000187:drug effects*; D011134:Polysaccharides / Q000737:chemistry*; D020942:Shiitake Mushrooms / Q000737:chemistry*
D000970:Antineoplastic Agents; D011134:Polysaccharides