A new HLA-A*03 null allele - A*03:162N caused by an exon 4 insertion and discovered during an external quality assessment exercise.
HLA-A*03:162N differs from A*03:01:01:01 by an exon 4, 664-665insCATG causing E198A and A199X.
Department of Immunology, Genetics and Pathology, Uppsala University and University Hospital, Uppsala, Sweden.
M
M
Bengtsson
J
J
Street
J
J
Johnson
C
C
Harvey
S
S
Corbin
C
C
Darke
D001782:Blood Donors; D017931:DNA Primers / Q000235:genetics; D015444:Exercise; D005091:Exons / Q000235:genetics; D005787:Gene Frequency; D015791:HLA-A3 Antigen / Q000235:genetics*; D006801:Humans; D016254:Mutagenesis, Insertional; D011785:Quality Assurance, Health Care; D017422:Sequence Analysis, DNA; D006113:United Kingdom; D044465:White People
D017931:DNA Primers; C487960:HLA-A*03 antigen; D015791:HLA-A3 Antigen
HLA-A*03:162N; exon 4 insertion; external quality assessment