Assessment of toxicity and potential risk of butene-fipronil using Drosophila melanogaster, in comparison to nine conventional insecticides.
The toxicities of butene-fipronil to Drosophila melanogaster were evaluated, in comparison to nine conventional insecticides. According to the mean LD50 values of the larvae from CS, w(1118) and Oregan strains, butene-fipronil,abamectin, spinosad and chlorpyrifos exhibited high levels of toxicity. Imidacloprid, α-cypermethrin and clothianidin showed middle levels of toxicity. And acephate,methomyl and acetamiprid had low levels of toxicity. To the adults, butene-fipronil, α-cypermethrin, spinosad, and chlorpyrifos were relatively more toxic, whereas acephate,methomyl, acetamiprid, imidacloprid, clothianidin and abamectin were relatively less toxic. Butene-fipronil and abamectin were more toxic to larvae. In contrast, spinosad,a-cypermethrin, and clothianidin were more toxic to adults.Moreover, the toxic risk assessment using a risk quotient value revealed that butene-fipronil was safe to D. melanogaster adults. Thus, our results suggested that butene-fipronil is harmful to D. melanogaster larvae, but it is relatively safe to the adults.
Muhammad Shahid
MS
Arain
Xing-Xing
XX
Hu
Guo-Qing
GQ
Li
D000818:Animals; D004331:Drosophila melanogaster; D006846:Hydrocarbons, Halogenated / Q000633:toxicity*; D007306:Insecticides / Q000633:toxicity*; D011720:Pyrazoles / Q000633:toxicity*; D018570:Risk Assessment; D018675:Toxicity Tests
C561658:1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-5-(2-methylamino)-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile; D006846:Hydrocarbons, Halogenated; D007306:Insecticides; D011720:Pyrazoles