Molecular targeting of mutagenic AID and APOBEC deaminases.
Departments of Medicine and Biochemistry and Molecular Biophysics; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA.
Christopher S
CS
Nabel
Departments of Medicine and Biochemistry and Molecular Biophysics; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA.
Emily K
EK
Schutsky
Departments of Medicine and Biochemistry and Molecular Biophysics; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA.
Rahul M
RM
Kohli
D000818:Animals; D003564:Cytidine Deaminase / Q000378:metabolism*; D004247:DNA / Q000378:metabolism*; D006801:Humans; D012313:RNA / Q000378:metabolism*
D012313:RNA; D004247:DNA; D003564:Cytidine Deaminase
DNA damage; DNA deaminases; class switch recombination; kataegis; mutagenesis; nucleic acid enzymology; retroviral restriction; somatic hypermutation