Classification and comparative study of vitiligo in Southeast of Turkey with biochemical and immunological parameters.
OBJECTIVE
To investigate classification and comparative with biochemical and immunological parameters of vitiligo disease in Southeast of Turkey.


METHODS
148 patients who referred to the Department & Dermatology and Venereology with the complaint of vitiligo were selected. All patients gave informed consent for participation in the study. The patients were classified according to types of the skin. The complete blood cell and biochemical laboratory tests, ASO, CRP, RF, ANA, thyroid hormone levels were examined.


RESULTS
In the evaluation of 148 vitiligo patients; we didn't observe any significant difference between age and sex groups. We observed the maximum number of patients in the ages of 20-29 years and the most common types of clinical and focal types. We compared the childeren and adult patients according to their skin types, the difference was significant. We viewed that the onset of the disease commonly first in the face area. Koebner phenomenon 17 (11.48%), halo nevus 5 (3.38%) and leucotrichia 5 (3.38%) of patients were positive.


CONCLUSIONS
Vitiligo is associated with loss of color by the destruction of melanocytes. The incidence of vitiligo is 1-2% and is found in every race. This study is important for the reason of the first research which evaluates vitiligo patients in southeast of Turkey.
Department of Dermatology and Venereology, Veni Vidi Hospital; Medicine Faculty, Dicle University, Turkey.
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Kalkanli
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Kalkanli
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D000368:Aged; D001327:Autoimmune Diseases / Q000453:epidemiology; D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D006801:Humans; D007223:Infant; D008875:Middle Aged; D055882:Nevus, Halo / Q000453:epidemiology; D009928:Organ Specificity; D012880:Skin Pigmentation; D014421:Turkey / Q000453:epidemiology; D014820:Vitiligo / Q000097:blood / Q000145:classification* / Q000453:epidemiology / Q000276:immunology; D055815:Young Adult
D015415:Biomarkers