The effect of temperature on Anopheles mosquito population dynamics and the potential for malaria transmission.
The parasites that cause malaria depend on Anopheles mosquitoes for transmission; because of this, mosquito population dynamics are a key determinant of malaria risk. Development and survival rates of both the Anopheles mosquitoes and the Plasmodium parasites that cause malaria depend on temperature, making this a potential driver of mosquito population dynamics and malaria transmission. We developed a temperature-dependent, stage-structured delayed differential equation model to better understand how climate determines risk. Including the full mosquito life cycle in the model reveals that the mosquito population abundance is more sensitive to temperature than previously thought because it is strongly influenced by the dynamics of the juvenile mosquito stages whose vital rates are also temperature-dependent. Additionally, the model predicts a peak in abundance of mosquitoes old enough to vector malaria at more accurate temperatures than previous models. Our results point to the importance of incorporating detailed vector biology into models for predicting the risk for vector borne diseases.
Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America ; Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America.
Lindsay M
LM
Beck-Johnson
William A
WA
Nelson
Krijn P
KP
Paaijmans
Andrew F
AF
Read
Matthew B
MB
Thomas
Ottar N
ON
Bjørnstad
D000465:Algorithms; D000818:Animals; D000852:Anopheles / Q000469:parasitology; D005260:Female; D006801:Humans; D007814:Larva; D008288:Malaria / Q000635:transmission*; D008962:Models, Theoretical; D011156:Population Density; D011157:Population Dynamics; D013696:Temperature