Combining conventional chemotherapy and γδ T cell-based immunotherapy to target cancer-initiating cells.
According to common beliefs, conventional anticancer chemotherapy is deleterious for the immune system. We have recently provided in vitro evidence indicating that conventional chemotherapy may potentiate, rather than impair, the long-term efficacy of γδ T cell-based anticancer immunotherapy.
Biomedical Research Centre; University of Palermo; Palermo, Italy ; Department of Surgical and Anatomical Disciplines; University of Palermo; Palermo, Italy.
Matilde
M
Todaro
Serena
S
Meraviglia
Nadia
N
Caccamo
Giorgio
G
Stassi
Francesco
F
Dieli
NKG2D; TRAIL; Vγ9Vδ2 T cells; colon cancer-initiating cells; cytotoxicity