Isolation and identification of flavonoids from Coreopsis lanceolata L. petals.
The methanol extract of Coreopsis lanceolata L. petals was acid-hydrolysed, and 7,3',4'-trihydroxy-8-methoxyflavanone (1) and 6,3',4'-trihydroxy-7-methoxyaurone (leptosidin) (2) were successfully isolated. The structure of compound 1 is designated to flavanone based on X-ray crystallographic analysis and NMR spectroscopic analysis. Compound 1 showed high-antioxidant effects based on diphenylpicrylhydrazyl radical scavenging assay (94.3% scavenging rate) and superoxide dismutase-like activity assay (23.9% inhibition rate).
a Graduate School of Systems Engineering, Kinki University , Umenobe 1, Takaya, Higashi-Hiroshima 739-2116 , Japan.
Yoshiharu
Y
Okada
Mari
M
Okita
Yoshihiro
Y
Murai
Yuka
Y
Okano
Masato
M
Nomura
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001204:Ascorbate Oxidase; D001572:Benzofurans; D031945:Coreopsis / Q000737:chemistry*; D044950:Flavanones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D035264:Flowers / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D013482:Superoxide Dismutase / Q000378:metabolism
C000591062:6,3',4'-trihydroxy-7-methoxyaurone; C000590963:7,3',4'-trihydroxy-8-methoxyflavanone; D000975:Antioxidants; D001572:Benzofurans; D044950:Flavanones; D016166:Free Radical Scavengers; D010936:Plant Extracts; D001204:Ascorbate Oxidase; D013482:Superoxide Dismutase