DNA methylation score is predictive of myeloma cell sensitivity to 5-azacitidine.
CHU Montpellier, Institute of Research in Biotherapy, Montpellier, France; INSERM, U1040, Montpellier, France.
Jerome
J
Moreaux
Angelique
A
Bruyer
Jean-Luc
JL
Veyrune
Hartmut
H
Goldschmidt
Dirk
D
Hose
Bernard
B
Klein
D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology* / Q000627:therapeutic use; D001374:Azacitidine / Q000494:pharmacology* / Q000627:therapeutic use; D019175:DNA Methylation; D004354:Drug Screening Assays, Antitumor; D057890:Epigenomics; D006801:Humans; D009101:Multiple Myeloma / Q000188:drug therapy* / Q000235:genetics*; D011237:Predictive Value of Tests
D000964:Antimetabolites, Antineoplastic; D001374:Azacitidine
drug sensitivity prediction; epigenetics; gene arrays; gene expression; myeloma