Synthesis and applications of α-trifluoromethylated alkylboron compounds.
RBF3 K is a chemist's BFF: A metal-free synthetic route to unprecedented organoboron compounds bearing an α-trifluoromethyl substituent, employing a variety of trifluoroborate (RBF3 K) starting materials, is reported. These substrates represent the first isolated α-trifluoromethylated alkylboron building blocks, and these reagents lead to a variety of useful bench-stable, synthetic intermediates. Pin=pinacol.
Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104-6323 (USA).
O Andreea
OA
Argintaru
DaWeon
D
Ryu
Ioana
I
Aron
Gary A
GA
Molander
D001895:Boron / Q000737:chemistry*; D002384:Catalysis; D008745:Methylation; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D001895:Boron
boron; diazo compounds; silanes; synthetic methods; trifluoromethylation