Extracorporeal shock wave therapy in musculoskeletal disorders: a review.
Regenerative therapy is one of the most challenging and intriguing branches of modern medicine. Basic research has demonstrated the effectiveness of extracorporeal shockwaves (ESWT) in stimulating biological activities that involve intra-cell and cell-matrix interactions. These interactions are at the basis of the current clinical applications, and open the horizons to new applications in tissue regeneration. It is also feasible that shock waves could be used to treat various orthopaedic pathologies, removing the need for surgery. However, suitable translational studies need to be performed before ESWT can become a valid alternative to surgery.
Clinica Ortopedica dell' Università degli Studi di Milano, Istituto Ortopedico Galeazzi IRCCS, Milan, Italy.
Pietro
P
Romeo
Vito
V
Lavanga
Davide
D
Pagani
Valerio
V
Sansone
D001847:Bone Diseases / Q000628:therapy; D002908:Chronic Disease; D017102:Fracture Healing; D019220:High-Energy Shock Waves / Q000627:therapeutic use*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000096:biosynthesis; D009128:Muscle Spasticity / Q000628:therapy; D009140:Musculoskeletal Diseases / Q000503:physiopathology / Q000628:therapy*; D017202:Myocardial Ischemia / Q000628:therapy; D009569:Nitric Oxide / Q000096:biosynthesis; D015398:Signal Transduction; D012883:Skin Ulcer / Q000628:therapy; D052256:Tendinopathy / Q000628:therapy
D036341:Intercellular Signaling Peptides and Proteins; D009569:Nitric Oxide