Is there a role for postoperative radiotherapy following open partial laryngectomy when prognostic factors on the pathological specimen are unfavourable? A survey of head and neck surgical/radiation oncologists.
Our aim was to survey the opinions of Italian radiation and ENT oncologists regarding the role of postoperative radiotherapy (PRT) and the appropriate dose to be given to patients with remnant larynx (RL) after open partial laryngectomy (OPL). The radio-oncologists (ROs) of the Italian Radiation-Oncologist Association (AIRO) and the ENTs of the Head-Neck Oncology Society (AIOCC-IHNS) were contacted through a SurveyMonkey online interface questionnaire. There were 148 usable responses. The majority of ROs recommended PRT in the case of positive/close margins (R(+)/R(close)) or in the case of initial involvement of thyroid cartilage (pT3(tci)). In the same cases, ENTs prefer a "watch and wait" policy (w&w). Both disciplines recommended w&w in the case of negative margins (R(-)). Finally, the majority of RO s recommended irradiating RL with 62-66 Gy in R(+), with 56-66 Gy (61.4%) in R(close) and with 56-60 Gy (34%) in pT3(tci). In Conclusion, OPL raises new considerations about PRT.
Radiation Oncology Department, AO "S. Croce e Carle", Cuneo, Italy;
E G
EG
Russi
G
G
Sanguineti
F
F
Chiesa
P
P
Franco
G
G
Succo
A
A
Merlotti
M
M
Ansarin
A
A
Melano
D
D
Alterio
S
S
Pergolizzi
M
M
Buglione
A
A
Reali
U
U
Ricardi
R
R
Corvò
D003131:Combined Modality Therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods; D008495:Medical Oncology; D011182:Postoperative Care; D010818:Practice Patterns, Physicians'; D011379:Prognosis; D011871:Radiology; D013043:Specialties, Surgical; D011795:Surveys and Questionnaires
Conservative laryngectomy; Head and neck cancer; Larynx; Partial laryngectomy; Postoperative radiotherapy