Statistical tools and R software for cancer driver probabilities.
This chapter provides a description and illustration of CancerMutationAnalysis and Cancer MutationMCMC, two open source R packages specifically designed for the analysis of somatic mutations in cancer genome studies, at both the gene and gene-set levels.
Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA.
Giovanni
G
Parmigiani
Simina
S
Boca
Jie
J
Ding
Lorenzo
L
Trippa
D000465:Algorithms; D019295:Computational Biology; D003627:Data Interpretation, Statistical; D052138:Genes, Neoplasm; D056726:Genetic Association Studies; D006801:Humans; D008390:Markov Chains; D008957:Models, Genetic; D058977:Molecular Sequence Annotation; D009010:Monte Carlo Method; D009369:Neoplasms / Q000235:genetics*; D017354:Point Mutation; D012984:Software