Central nervous system involvement in scrub typhus.
Scrub typhus is an emerging infectious disease in India. Among its protean clinical manifestations, central nervous system involvement is common. In this prospective observational study, altered sensorium, headache, seizures and aseptic meningitis were found to be common central nervous system manifestations. Prompt treatment with doxycycline reduces morbidity and mortality.
Assistant Professor, Department of Internal Medicine, Christian Medical College, Vellore, India.
Harikishan
H
Boorugu
Anugrah
A
Chrispal
K G
KG
Gopinath
Sara
S
Chandy
John Jude
JJ
Prakash
Asha Mary
AM
Abraham
O C
OC
Abraham
Kurien
K
Thomas
D000328:Adult; D002493:Central Nervous System Diseases / Q000134:cerebrospinal fluid / Q000453:epidemiology / Q000382:microbiology*; D002555:Cerebrospinal Fluid; D021821:Communicable Diseases, Emerging / Q000453:epidemiology; D004318:Doxycycline / Q000627:therapeutic use*; D005260:Female; D005335:Fever of Unknown Origin / Q000150:complications / Q000188:drug therapy; D006261:Headache / Q000209:etiology; D006801:Humans; D007075:Immunoglobulin M; D007194:India / Q000453:epidemiology; D008297:Male; D008582:Meningitis, Aseptic / Q000134:cerebrospinal fluid; D012285:Orientia tsutsugamushi / Q000276:immunology / Q000302:isolation & purification*; D015995:Prevalence; D011446:Prospective Studies; D012612:Scrub Typhus / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology; D016896:Treatment Outcome
D007075:Immunoglobulin M; D004318:Doxycycline
Aseptic meningitis; central nervous system; scrub typhus