New bone formation in a bone defect associated to dental implant using absorbable or non-absorbable membrane in a dog model.
The aim of this research was to determine the bone formation capacity in fenestration defects associated with dental implants using absorbable and non-absorbable membranes. Six dogs were used in the study. In both tibias of each animal 3 implants were installed, and around these 5 mm circular defects were created. The defects were covered with absorbable membranes (experimental group 1), non-absorbable membranes (experimental group 2), and the third defect was not covered (control group). At 3 and 8 weeks post-surgery, the animals were euthanized and the membranes with the bone tissue around the implants were processed for histological analysis. The statistical analysis was conducted with Tukey's test, considering statistical significance when p<0.1. Adequate bone repair was observed in the membrane-covered defects. At 3 weeks, organization of the tissue, bone formation from the periphery of the defect and the absence of inflammatory infiltrate were observed in both experimental groups, but the defect covered with absorbable membrane presented statistically greater bone formation. At 8 weeks, both membrane-covered defects showed adequate bone formation without significant differences, although they did in fact present differences with the control defect in both periods (p>0.1). In the defects without membrane, continuous connective tissue invasions and bone repair deficiency were observed. There were no significant differences in the characteristics and volume of the neoformed bone in the defects around the implants covered by the different membranes, whereas the control defects produced significantly less bone. The use of biological membranes contributes to bone formation in three-wall defects.
Division of Oral and Maxillofacial Surgery, Piracicaba Dental School, State University of Campinas Brazil.
Maria de Almeida
Mde A
Lopez
Sergio
S
Olate
Antonio
A
Lanata-Flores
Leandro
L
Pozzer
Lucas
L
Cavalieri-Pereira
Mario
M
Cantín
Bélgica
B
Vásquez
José
J
de Albergaria-Barbosa
D020341:Absorbable Implants / Q000009:adverse effects; D000818:Animals; D015921:Dental Implants / Q000009:adverse effects; D004285:Dogs; D016557:Guided Tissue Regeneration, Periodontal / Q000295:instrumentation* / Q000379:methods; D008567:Membranes, Artificial; D023421:Models, Animal; D016348:Osseointegration; D010012:Osteogenesis; D011474:Prosthesis Design; D013977:Tibia / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors; D014025:Titanium
D015921:Dental Implants; D008567:Membranes, Artificial; D014025:Titanium
Bone regeneration; biological membrane; bone defect