Bubonic lymphogranuloma venereum with multidrug treatment failure.
A patient with proctitis and inguinal buboes diagnosed with lymphogranuloma venereum (LGV) was treated with doxycycline 21 days, azithromycin 20 days and moxifloxacin for a further 12 days because of progressive worsening of inguinal symptoms. Despite extensive antibiotic treatment, the inguinal LGV lesions persisted; however, the patient recovered spontaneously after three months.
STI Unit, University Hospital Vall d'Hebron, Barcelona, Catalonia, Spain.
Martí
M
Vall-Mayans
Jenny
J
Isaksson
Estrella
E
Caballero
Beatriz
B
Sallés
Björn
B
Herrmann
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001372:Aza Compounds / Q000627:therapeutic use; D017963:Azithromycin / Q000627:therapeutic use; D002692:Chlamydia trachomatis / Q000235:genetics / Q000302:isolation & purification*; D004318:Doxycycline / Q000627:therapeutic use; D024841:Fluoroquinolones; D018451:Homosexuality, Male; D006801:Humans; D008219:Lymphogranuloma Venereum / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D000077266:Moxifloxacin; D058885:Multilocus Sequence Typing; D011349:Proctitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D011804:Quinolines / Q000627:therapeutic use; D060888:Real-Time Polymerase Chain Reaction; D017211:Treatment Failure
D000900:Anti-Bacterial Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D011804:Quinolines; D017963:Azithromycin; D004318:Doxycycline; D000077266:Moxifloxacin
Chlamydia trachomatis; LGV; Sexually transmitted infection; bubo; lymphogranuloma venereum; treatment failure