Ablation of musculoskeletal metastases: pain palliation, fracture risk reduction, and oligometastatic disease.
Thermal ablation is an effective, minimally invasive alternative to conventional therapies in the palliation of painful musculoskeletal metastases and an emerging approach to obtain local tumor control in the setting of limited metastatic disease. Various thermal ablation technologies have been applied to bone and soft tissue tumors and may be used in combination with percutaneous cement instillation for skeletal lesions with or at risk for pathologic fracture. This article reviews current practices of percutaneous ablation of musculoskeletal metastases with an emphasis on radiofrequency ablation and cryoablation of painful skeletal metastases.
Department of Radiology, Mayo Clinic, Rochester, MN. Electronic address: kurup.anil@mayo.edu.
Anil Nicholas
AN
Kurup
Matthew R
MR
Callstrom
D055011:Ablation Techniques / Q000009:adverse effects / Q000379:methods; D001859:Bone Neoplasms / Q000150:complications / Q000556:secondary / Q000601:surgery*; D017115:Catheter Ablation; D003452:Cryosurgery; D050723:Fractures, Bone / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D019042:Muscle Neoplasms / Q000150:complications / Q000556:secondary / Q000601:surgery*; D010146:Pain / Q000209:etiology / Q000517:prevention & control*; D010166:Palliative Care; D018579:Patient Selection; D011237:Predictive Value of Tests; D012307:Risk Factors; D025321:Surgery, Computer-Assisted / Q000009:adverse effects / Q000379:methods; D016896:Treatment Outcome
Radiofrequency ablation; bone tumor; cryoablation; oligometastasis