Lipid resuscitation in pediatric patients - need for caution?
A 3-year-old child was successfully resuscitated following bupivacaine cardiotoxicity with 20% intravenous lipid emulsion (ILE). Large volume of ILE was used targeting clinically adequate perfusion. Subsequently, there were features of ventilation/perfusion (V/P) mismatch.
Department of Anesthesiology, Jubilee Mission Medical College & Research Institute, Thrissur, Kerala, India.
Usha
U
Shenoy
John
J
Paul
Deepu
D
Antony
D000779:Anesthetics, Local / Q000009:adverse effects; D002045:Bupivacaine / Q000009:adverse effects; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D002675:Child, Preschool; D004837:Epinephrine / Q000627:therapeutic use; D005217:Fat Emulsions, Intravenous / Q000627:therapeutic use*; D005260:Female; D006333:Heart Failure / Q000139:chemically induced / Q000188:drug therapy; D006801:Humans; D007866:Leg / Q000601:surgery; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
D000779:Anesthetics, Local; D005217:Fat Emulsions, Intravenous; D014662:Vasoconstrictor Agents; D002045:Bupivacaine; D004837:Epinephrine
V/P mismatch; bupivacaine; inadvertent ILE overdose; toxicity