Syndrome of inappropriate antidiuretic hormone secretion associated with olfactory neuroblastoma.
This study reports a patient having olfactory neuroblastoma complicated by syndrome of inappropriate antidiuretic hormone secretion. Olfactory neuroblastoma is a rare tumor that begins in the olfactory membrane. Only 10 cases have been reported previously. Because of having nonspecific symptoms, most patients manifest at an advanced stage at the time of diagnosis. Olfactory neuroblastoma may show local invasion and/or distant metastasis. We demonstrated preoperatively clinical and biochemical parameters consistent with antidiuretic hormone syndrome turned to normal ranges after the treatment. Surgery, chemotherapy, and radiotherapy are the choices of treatment; among these, surgery is an indispensible treatment.
From the Departments of *Otorhinolaryngology-Head and Neck Surgery, and †Pathology, Pendik Training and Research Hospital, Marmara University, Istanbul, Turkey.
Ali Cemal
AC
Yumusakhuylu
Adem
A
Binnetoglu
Muhammet Fatih
MF
Topuz
Emine Baş
EB
Bozkurtlar
Tekin
T
Baglam
Murat
M
Sari
D000328:Adult; D018304:Esthesioneuroblastoma, Olfactory / Q000150:complications*; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000150:complications*; D008297:Male; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000150:complications*