[Infections transmitted from the mother to the fetus: diagnostic issues and management of pregnancy].
Some infections are considered as feared risks during pregnancy. These infections may lead to severe damage of the fetus or the newborn depending on the infectious agent and the term of pregnancy where the infection occurred. Antenatal screening (in France it concerns toxoplasmosis, rubella, syphilis and hepatitis B) play an important role in prevention and management of vertically transmissible infections. However, biological diagnosis is also essential when maternal/neo-natal clinical symptoms or abnormal ultrasound findings are observed. In this article we chose to focus on rubella, varicella, syphilis, toxoplasmosis, hepatitis B and cytomegalovirus and parvovirus infections.
Laboratoire de virologie du GH Paris-Sud, Centre national de référence des infections rubéoleuses materno-fœtales, AP-HP, Hôpital Paul Brousse, Villejuif, France.
Christelle
C
Vauloup-Fellous
Elise
E
Bouthry
Liliane
L
Grangeot-Keros
D002644:Chickenpox / Q000175:diagnosis / Q000628:therapy / Q000635:transmission; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000628:therapy / Q000635:transmission; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D010322:Parvoviridae Infections / Q000175:diagnosis / Q000628:therapy / Q000635:transmission; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000628:therapy*; D012409:Rubella / Q000175:diagnosis / Q000628:therapy / Q000635:transmission; D014123:Toxoplasmosis / Q000175:diagnosis / Q000628:therapy / Q000635:transmission
biological diagnosis; management; materno-fetal infections; prevention