Intracranial pseudolymphoma presenting with grand mal seizures.
Primary central nervous system lymphoproliferative disorders comprise a heterogenous group of intracranial disease, predominantly of the high-grade non-Hodgkin's lymphoma type. We report a 56-year-old woman who developed new-onset grand mal seizures and was found to have two small uniformly enhancing dural-based lesions, which were radiologically concerning for meningiomas. Biopsy demonstrated findings consistent with benign, reactive lymphoid tissue. The patient's seizures resolved post-operatively. To our knowledge, this is the first reported patient with intracranial pseudolymphoma presenting as grand mal seizures. This case highlights this rare differential consideration in a patient with symptomatic dural-based lesion.
Wake Forest School of Medicine, Department of Neurology, 1 Medical Center Boulevard, Box 2669, Winston Salem, NC 27157, USA. Electronic address: rstrowd1@jhmi.edu.
Roy E
RE
Strowd
Wake Forest School of Medicine, Department of Neurosurgery, Winston Salem, NC, USA.
Alexander K
AK
Powers
Wake Forest School of Medicine, Department of Pathology, Winston Salem, NC, USA.
Michael W
MW
Beaty
Wake Forest School of Medicine, Department of Neurosurgery, Winston Salem, NC, USA.
Thomas L
TL
Ellis
D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004830:Epilepsy, Tonic-Clonic / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D019310:Pseudolymphoma / Q000150:complications / Q000175:diagnosis*
Intracranial pseudolymphoma; Meningioma; Neuroradiology; Seizure