Palladium-catalyzed stereospecific cross-coupling of enantioenriched allylic alcohols with boronic acids.
In the presence of 2.5 mol% Pd2(dba)3-TMEDA (1 : 4), a range of enantioenriched allylic alcohols smoothly coupled with boronic acids in a highly regioselective fashion with inversion of configuration to afford structurally diverse alkenes in good yields with perfect retention of ee.
Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. tiansk@ustc.edu.cn.
Hai-Bian
HB
Wu
Xian-Tao
XT
Ma
Shi-Kai
SK
Tian