title: Use of GnRH-agonists for medical management of reproductive disorders in birds.
abstract: Pet birds suffer from a wide range of reproductive conditions and diseases. Chronic egg laying, egg binding, and excessive reproductive activities are common problems. Veterinarians may prescribe behavior modification, changes in captive care, and medical therapy to curb these behaviors. Surgical removal of the oviduct is effective at stopping egg production; however, it is a specialized surgery that carries surgical and anesthetic-related risks. The inability to surgically remove the ovary in birds may result in persistent ovarian activity and secondary complications. Therefore, hormone therapy as an adjunct or main therapeutic approach, using sustained-release GnRH agonists, shows promise in pet birds.
authors.affiliation: Special Species Health Service, Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, 2015 Linden Drive, Madison, WI 53706, USA. Electronic address: cmans@vetmed.wisc.edu.
authors.forename: Christoph
authors.initials: C
authors.lastname: Mans
authors.forename: Anthony
authors.initials: A
authors.lastname: Pilny
mesh_terms: D000818:Animals; D001715:Bird Diseases / Q000188:drug therapy*; D001717:Birds; D016503:Drug Delivery Systems / Q000662:veterinary; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists*; D008297:Male; D012098:Reproduction / Q000187:drug effects*
chemical_list: D007987:Gonadotropin-Releasing Hormone
keywords: Deslorelin; GnRH agonist; Leuprolide acetate; Lupron; Reproductive disorders