title: Risk factors for mortality in burn children.
abstract: Studies about risk factors for mortality in burn children are scarce. We conducted this study to evaluate the risk factors for mortality in pediatric burn patients. We included 110 patients. Mean age was 31.5 months (range: 1 to 204). The burn surface was between 1% and 95%(median 27%) Type of burn was: A or superfitial in 39 patients (36%), AB or intermediate in 19 (17%), and B or full thickness in 52 (47%). Inhalatory injury was present in 52 patients (47%). Invasive procedures were: venous catheter, 90 patients (82%), arterial catheter, 83 patients (75.5%), urinary catheter, 86 patients (78%), and mechanical ventilation, 75 patients (68%). In 84 patients, 128 infections were diagnosed. in 53 cases (48%). Multiresistant Pseudomonas aeruginosa and Acynetobacter baumannii were the most common organisms isolated. The median length of hospital stay was 33 days (r: 8-139 days). Seventeen patients (15%) died and 14 of them of infection-related causes. Age ≤ <4 years, Garcés 4, full thickness burn, ≥ 40% burn surface, presence of inhalatory syndrome, use of venous catheter, arterial catheter, urinary catheter and mechanical ventilation, positive blood cultures, colistin use in documented multiresistant infections, antifungal use and graft requirement, were identified as risks factors for mortality in the univariate analysis. By multivariate analysis: age ≤ 4 years, Garcés 4, colistin use in multiresistant infections, mechanical ventilation and graft requirement were independent variables related with mortality.
  
  
  CONCLUSIONS
  In this series of burn children age ≤ 4 years, Garces index score 4, colistin use in documented multiresistant infections, mechanical ventilation and graft requirement were identified as independent variables related with mortality.
authors.affiliation: Hospital de Pediatría J P Garrahan, Argentina. Electronic address: margris2@yahoo.com.ar.
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Rosanova
authors.affiliation: Fundación Centro de Estudios Infectológicos, Argentina.
authors.forename: Daniel
authors.initials: D
authors.lastname: Stamboulian
authors.affiliation: Director Maestría Farmacología clínica de la Universidad Abierta Interamericana, Argentina.
authors.forename: Roberto
authors.initials: R
authors.lastname: Lede
mesh_terms: D000293:Adolescent; D001118:Argentina / Q000453:epidemiology; D002056:Burns / Q000382:microbiology / Q000401:mortality*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007902:Length of Stay; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors
keywords: Burns; Children; Mortality