title: Clinical features of rapidly progressive bilateral sensorineural hearing loss.
abstract: CONCLUSIONS
  Rapidly progressive bilateral sensorineural hearing loss (SNHL) often develops as a symptom of intracranial diseases or systemic vasculitis. For early diagnosis and treatment of these potentially fatal diseases, a history of hearing deterioration within 2 months and associated symptoms may be important.
  
  
  OBJECTIVE
  To reveal clinical features and causative diseases for rapidly progressive bilateral SNHL.
  
  
  METHODS
  The inclusion criterion was patients with bilateral progressive SNHL, who had experienced difficulty in daily conversation within 4 days to 1 year after the onset of hearing loss awareness. This study was a retrospective evaluation of 12 patients with rapidly progressive bilateral SNHL who visited our hospital between 2007 and 2011.
  
  
  RESULTS
  The causative disease for hearing loss was identified in 11 of 12 patients; intracranial lesions including nonbacterial meningitis, meningeal metastasis of lymphoma, and superficial siderosis in 4 patients, systemic vasculitis in 2, auditory neuropathy spectrum disorder in 1, and an isolated inner ear disorder in 4. Relatively rapid hearing deterioration within 2 months showed a significant association in six patients with an intracranial lesion or systemic vasculitis. Moreover, all these six patients complained of dizziness and/or non-cochleovestibular symptoms such as fever, headache, and/or altered mental state in addition to hearing loss.
authors.affiliation: Department of Otolaryngology, Kobe City Medical Center General Hospital , Kobe.
authors.forename: Ippei
authors.initials: I
authors.lastname: Kishimoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamazaki
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Naito
authors.forename: Shogo
authors.initials: S
authors.lastname: Shinohara
authors.forename: Keizo
authors.initials: K
authors.lastname: Fujiwara
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kikuchi
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kanazawa
authors.forename: Risa
authors.initials: R
authors.lastname: Tona
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Harada
mesh_terms: D000328:Adult; D000368:Aged; D001927:Brain Diseases / Q000150:complications; D018450:Disease Progression; D005260:Female; D006313:Hearing Loss, Central / Q000150:complications; D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D056647:Systemic Vasculitis / Q000150:complications