title: Rhodium-catalyzed direct addition of aryl C-H bonds to nitrosobenzenes at room temperature.
abstract: An unprecedented Rh-catalyzed direct addition of aryl C-H bonds to nitrosobenzenes has been developed under very mild reaction conditions (room temperature). The reaction is highly step-, atom-, and redox-economic and compatible with air and water to N-selectively provide a variety of N-diarylhydroxylamines in good to excellent yields. More importantly, this process may provide a new direction for C-N bond formation through direct C(sp(2))-H functionalization.
authors.affiliation: Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 555 Zu Chong Zhi Road, Shanghai 201203, PR China.
authors.forename: Bing
authors.initials: B
authors.lastname: Zhou
authors.forename: Juanjuan
authors.initials: J
authors.lastname: Du
authors.forename: Yaxi
authors.initials: Y
authors.lastname: Yang
authors.forename: Huijin
authors.initials: H
authors.lastname: Feng
authors.forename: Yuanchao
authors.initials: Y
authors.lastname: Li
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D006898:Hydroxylamines / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D009603:Nitroso Compounds / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013696:Temperature
chemical_list: D006898:Hydroxylamines; D009603:Nitroso Compounds; D009942:Organometallic Compounds; D012238:Rhodium; C012456:nitrosobenzene