title: [Crystalline keratopathy due to kappa chains in a monoclonal gammopathy].
abstract: METHODS
  The following case shows corneal crystal formation in a patient in whom thee systemic work-up led to the diagnosis of a monoclonal gammopathy with increased monoclonal immunoglobulin G (IgG). We present the corneal signs and subsequent haematological investigations undertaken to establish this important association.
  
  
  CONCLUSIONS
  Systemic work-up of a patient with corneal deposits showed a monoclonal gammopathy with increased monoclonal immunoglobulin (IgG-type kappa). Corneal crystals, a rare, but significant, clinical finding, may be the initial presentation in a patient with monoclonal gammopathy.
authors.affiliation: Servicio de Oftalmología, Hospital Esperit Sant, Santa Coloma de Gramenet, Barcelona, España. Electronic address: jcarlosmesa@mixmail.com.
authors.forename: J C
authors.initials: JC
authors.lastname: Mesa-Gutiérrez
authors.forename: A
authors.initials: A
authors.lastname: Rouras-López
authors.forename: V
authors.initials: V
authors.lastname: Amías-Lamana
authors.forename: J
authors.initials: J
authors.lastname: Hoyos-Chacón
authors.forename: I
authors.initials: I
authors.lastname: Cabiró-Badimón
authors.forename: J
authors.initials: J
authors.lastname: Porta-Monnet
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001536:Bence Jones Protein / Q000652:urine; D003131:Combined Modality Therapy; D003318:Corneal Opacity / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D003460:Crystallization; D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000032:analysis*; D007676:Kidney Failure, Chronic / Q000209:etiology; D000077269:Lenalidomide; D008297:Male; D008558:Melphalan / Q000008:administration & dosage; D008875:Middle Aged; D010265:Paraproteinemias / Q000150:complications* / Q000175:diagnosis / Q000628:therapy / Q000652:urine; D010266:Paraproteins / Q000032:analysis*; D018918:Phacoemulsification; D011183:Postoperative Complications / Q000175:diagnosis; D011241:Prednisone / Q000008:administration & dosage; D066167:Slit Lamp; D013792:Thalidomide / Q000008:administration & dosage / Q000031:analogs & derivatives
chemical_list: D007145:Immunoglobulin kappa-Chains; D010266:Paraproteins; D013792:Thalidomide; D003520:Cyclophosphamide; D001536:Bence Jones Protein; D000077269:Lenalidomide; D008558:Melphalan; D011241:Prednisone
keywords: Cadenas ligeras kappa; Corneal crystals; Cristales corneales; Gammapatía monoclonal; Immunoglobulin G; Inmunoglobulina G; Kappa light chains; Monoclonal gammopathy