title: Hybrid ameloblastoma and adenomatoid odontogenic tumor: report of a case and review of hybrid variations in the literature.
abstract: Hybrid odontogenic tumors including 2 or more different histologic types have been documented, but their occurrences are not very common. We present a case of hybrid odontogenic tumor composed of ameloblastoma and adenomatoid odontogenic tumor (AOT) arising in the mandibular molar region of a 31-year-old Japanese woman who had a history of familial adenomatous polyposis. The tumor, measuring 10 mm in diameter, was surgically removed from the alveolar bone. Histopathologically, the tumor consisted of both follicular and plexiform types of ameloblastoma in which multiple and smaller foci of AOT were intermingled. There have been 3 reported cases of hybrid ameloblastoma and AOT, all of which presented unicystic types as ameloblastoma components. This, however, is the first report of a hybrid tumor containing an authentic solid-type ameloblastoma compartment and an AOT compartment in a patient with a background of familial adenomatous polyposis.
authors.affiliation: Assistant Professor, Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Yamazaki
authors.affiliation: Lecturer, Oral Pathology Section, Department of Surgical Pathology, Niigata University Hospital, Niigata, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Maruyama
authors.affiliation: Resident, Oral Pathology Section, Department of Surgical Pathology, Niigata University Hospital; Graduate Student, Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Abé
authors.affiliation: Graduate Student, Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
authors.forename: Hamzah
authors.initials: H
authors.lastname: Babkair
authors.affiliation: Assistant Professor, Division of Oral and Maxillofacial Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
authors.forename: Hajime
authors.initials: H
authors.lastname: Fujita
authors.affiliation: Professor, Division of Oral and Maxillofacial Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
authors.forename: Ritsuo
authors.initials: R
authors.lastname: Takagi
authors.affiliation: Assistant Professor, Division of Oral and Maxillofacial Radiology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
authors.forename: Jun-Ichi
authors.initials: J
authors.lastname: Koyama
authors.affiliation: Professor, Division of Oral and Maxillofacial Radiology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
authors.forename: Takafumi
authors.initials: T
authors.lastname: Hayashi
authors.affiliation: Associate Professor, Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences; Oral Pathology Section, Department of Surgical Pathology, Niigata University Hospital, Niigata, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Cheng
authors.affiliation: Professor, Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences; Oral Pathology Section, Department of Surgical Pathology, Niigata University Hospital, Niigata, Japan. Electronic address: tsaku@dent.niigata-u.ac.jp.
authors.forename: Takashi
authors.initials: T
authors.lastname: Saku
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000150:complications* / Q000601:surgery; D000328:Adult; D000564:Ameloblastoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D009808:Odontogenic Tumors / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D014057:Tomography, X-Ray Computed