title: Massive splenomegaly caused by cavernous hemangiomas associated with Klippel-Trenaunay syndrome: report of a case.
abstract: The etiology of Klippel-Trenaunay syndrome (KTS) is not well understood. Although splenic involvement is very rare in KTS, life-threatening events such as spontaneous rupture of a splenic hemangioma may occur. We recently performed elective splenectomy for massive splenomegaly causing uncontrollable abdominal pain in a woman with KTS. The extracted spleen weighed 4260 g, and cavernous hemangiomas in the spleen were found to be the cause of the splenomegaly. The patient's abdominal pain resolved after surgery and her postoperative course was uneventful, except for persistent bleeding from the bladder. This is a rare case of KTS with associated severe splenomegaly caused by hemangiomas.
authors.affiliation: Department of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan, take-misawa@jikei.ac.jp.
authors.forename: Takeyuki
authors.initials: T
authors.lastname: Misawa
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Shiba
authors.forename: Yuki
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: Yasuro
authors.initials: Y
authors.lastname: Futagawa
authors.forename: Toru
authors.initials: T
authors.lastname: Harada
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ikegami
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Yanaga
mesh_terms: D015746:Abdominal Pain / Q000209:etiology / Q000601:surgery; D000328:Adult; D005260:Female; D006392:Hemangioma, Cavernous / Q000209:etiology* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007715:Klippel-Trenaunay-Weber Syndrome / Q000150:complications* / Q000601:surgery*; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery*; D013163:Splenomegaly / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome