title: Co-existence of a large ovarian hemangioma and microscopic dysgerminoma in a 10-year old child.
abstract: Ovarian hemangioma is an uncommon ovarian tumor occurring in patients in different age groups. It is usually seen as small, asymptomatic mass, which is detected incidentally. On rare occasions, this type of tumor can be associated with other gynecological neoplasms. In this report, we present the clinicopathologic features of a case of ovarian hemangioma coexisting with multiple microscopic foci of dysgerminoma in a 10-year-old child. The patient presented with acute abdomen. Magnetic resonance imaging revealed a left ovarian mass and subsequent left salpingo-oophorectomy was performed. Grossly, the mass was 9.5 cm in diameter and contained hemorrhage and necrosis. Microscopic examination showed that the tumor was mostly composed of hemangioma. Additionally, there were three microscopic foci of dysgerminoma between the hemangioma and ovarian cortex. Immunohistochemical studies showed that dysgerminoma foci were positive for PLAP, Oct4 and CD117. To our knowledge, this is the first case of the above-described association ever reported.
authors.affiliation: Department of Pathology, Ondokuz Mayıs University, Faculty of Medicine, SAMSUN, TURKEY.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kefelı
authors.forename: Filiz
authors.initials: F
authors.lastname: Karagöz
authors.forename: Anais
authors.initials: A
authors.lastname: Malpica
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D002648:Child; D004407:Dysgerminoma / Q000473:pathology*; D005260:Female; D006391:Hemangioma / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor