title: [Incidence of congenital heart disease and factors associated with mortality in children born in two Hospitals in the State of Mexico].
abstract: We studied the incidence, survival, and risk factors for mortality in a cohort of infants for a period of five years, born in two hospitals, one a second-level General Hospital, the second a tertiary perinatal hospital, both in the City of Toluca. The analysis of survival was performed with the Kaplan-Meier method, and Cox regression was used to estimate the risk of death according to different factors. We found an overall incidence of 7.4 per 1,000 live births; in preterm infants, the rate was 35.6 per 1,000, and in term newborns it was 3.68 per 1,000. The most common heart disease was the ductus arteriosus in the overall group and in preterm infants; in term newborns the most common was the atrial septal defect. The specific mortality was 18.64%, follow-up was 579 days, where we found, according to Kaplan-Meier, survival of an average of 437.92 days, with 95% confidence intervals of 393.25 to 482.6 days, with a standard error of 22.79 days; the cumulative probability of survival was 0.741, with a standard error of 0.44. In Cox regression, two variables had a high hazard ratio (HR): these were the presence or absence of cyanosis and the hospital where they were treated as newborns.
authors.affiliation: Instituto de Salud del Estado de México e Instituto Materno Infantil del Estado de México, Toluca, Edo. de México. oeog45@gmail.com.
authors.forename: Gustavo Gabriel
authors.initials: GG
authors.lastname: Mendieta-Alcántara
authors.forename: Elia
authors.initials: E
authors.lastname: Santiago-Alcántara
authors.forename: Hugo
authors.initials: H
authors.lastname: Mendieta-Zerón
authors.forename: Ramsés
authors.initials: R
authors.lastname: Dorantes-Piña
authors.forename: Gabriela
authors.initials: G
authors.lastname: Ortiz de Zárate-Alarcón
authors.forename: Gloria A
authors.initials: GA
authors.lastname: Otero-Ojeda
mesh_terms: D015331:Cohort Studies; D005260:Female; D006330:Heart Defects, Congenital / Q000453:epidemiology* / Q000401:mortality; D006761:Hospitals; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000453:epidemiology* / Q000401:mortality; D008297:Male; D008800:Mexico; D012189:Retrospective Studies