title: Antibody suppression by zinc and nickel.
abstract: Rats were treated with zinc chloride and with nickel acetate 2 weeks prior to immunization withE. coli bacteriophageT-1; antibody titers to bacteriophageT-1 were reduced 500-2600-fold in metal-treated rats compared to titers found in untreated control animals. Examination of the effect of metal treatment on lymphocyte blastogenesis revealed a significant reduction in the number of blast cells in the spleens of metal-treated rats.
authors.affiliation: Department of Biology, University of San Francisco, 94117, San Francisco, CA.
authors.forename: S
authors.initials: S
authors.lastname: Mehrmofakham
authors.forename: L
authors.initials: L
authors.lastname: Treagan