title: Diagnosis of incidental gallbladder cancer after laparoscopic cholecystectomy: our experience.
abstract: BACKGROUND
  Gallbladder carcinoma is a rare high malignancy neoplasm. The incidence of intra or post-operative incidental gallbladder carcinoma diagnosis is estimated between 0,2 and 2,8%. Primary aim of our study is to evaluate incidental gallbladder carcinoma's incidence in our experience.
  
  
  METHODS
  We retrospectively reviewed our Surgery Division's experience about the totality of laparoscopic cholecystectomies with post-operative histological evidence of incidental gallbladder cancer. We evaluated patients' characteristics, surgical related variables, histological response, surgivcal radicalization characteristics and surgical outcome.
  
  
  RESULTS
  In the considered sample we observed 7 accidental gallbladder adenocarcinomas in post-operative histological examination. Pathological results were:1 pT1b N0 (G1), 2 pT2 N0 (G2), 2 pT2 N1 (G3b), 2 pT3 N1 (G3b) (Table 1). In 5 cases we performed neoplasm radicalization surgery with standard procedure revision. Two patients died before radicalization. Median global survival was 34 months.
  
  
  CONCLUSIONS
  With the increase of laparoscopic cholecystectomies both elective and urgent performed in our centre we observed also an increase of incidentally diagnosed gallbladder neoplasms. Early diagnosis, meticulous peri-operative study and accurate surgical strategy are essential factors to obtain good results in incidental gallbladder cancer.
authors.forename: Alessia G
authors.initials: AG
authors.lastname: Ferrarese
authors.forename: Mario
authors.initials: M
authors.lastname: Solej
authors.forename: Stefano
authors.initials: S
authors.lastname: Enrico
authors.forename: Alessandro
authors.initials: A
authors.lastname: Falcone
authors.forename: Silvia
authors.initials: S
authors.lastname: Catalano
authors.forename: Giada
authors.initials: G
authors.lastname: Pozzi
authors.forename: Silvia
authors.initials: S
authors.lastname: Marola
authors.forename: Valter
authors.initials: V
authors.lastname: Martino
mesh_terms: D000368:Aged; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D005706:Gallbladder Neoplasms / Q000175:diagnosis* / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies