title: [Evaluation of tuberculous patients' management when re-treated in Cotonou, Benin].
abstract: Retreatment of tuberculosis is the leading risk factor for drug resistance if the management is not adequate and complete. The objective of this study was to evaluate the management of cases of retreatment in Cotonou. This was a retrospective, descriptive cross type which covered a period of 5 years. Outcomes of retreatment cases were compared against those for new cases that were registered during the same period. We analyzed the cases of 389 retreatment patients and 4542 new cases. The success rates of treatment were generally satisfactory (80% vs. 86%, P=0.0001). Of adverse outcomes, the rate of loss of sight of was 12% versus 7%, P=0.26, the rate was 23% for cases of occasions. The failure rate was low and similar in both populations (2%). The retreatment regimen for patients with TB in Cotonou appears to give generally satisfactory results. The high loss to follow-up in case of retreatment means that a personalized therapeutic approach for such patients is needed in general and in particular in the case of defaulters.
authors.affiliation: Centre national hospitalier de pneumo-phtisiologie, 01 BP 321, Cotonou, Bénin; Faculté des sciences de la santé de Cotonou, Cotonou, Bénin. Electronic address: aggildas@yahoo.fr.
authors.forename: G
authors.initials: G
authors.lastname: Agodokpessi
authors.forename: G
authors.initials: G
authors.lastname: Ade
authors.forename: B H
authors.initials: BH
authors.lastname: Mbatchou Ngahane
authors.forename: S
authors.initials: S
authors.lastname: Ade
authors.forename: A P
authors.initials: AP
authors.lastname: Wachinou
authors.forename: F
authors.initials: F
authors.lastname: Bohissou
authors.forename: M
authors.initials: M
authors.lastname: Gninafon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001541:Benin / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019233:Retreatment; D012189:Retrospective Studies; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology* / Q000628:therapy*; D055815:Young Adult
keywords: Developing countries; Outcome; Pays en développement; Retraitement; Tuberculose; Tuberculosis retreatment