title: [Immediate results of combined treatment for soft tissue sarcomas including intraoperative radiation therapy].
abstract: Nowadays the most popular and justified, from oncological positions, method of treatment for soft tissue sarcomas is a combined approach with the use of conservative surgery followed by postoperative radiation therapy. In this regard, intraoperative radiation therapy (IORT) in a single dose of 10-20 Gy is a method that optimizes the role of radiation therapy in treatment of this pathology allowing precise localization of radiation zone within the "tumor bed", thereby minimizing damage of normal tissues and critical organs. The aim of the study was to investigate the effect of IORT on the frequency and structure of post-operative complications. Testing group (n = 49) was compared to the group without IORT (n = 57) and group with only surgery (n = 171). According to the study it was not obtained statistically significant differences in the incidence of postoperative complications in the groups (p = 0,57), not marked influence on the structure of post-operative complications.
authors.forename: P A
authors.initials: PA
authors.lastname: Ott
authors.forename: A V
authors.initials: AV
authors.lastname: Privalov
authors.forename: A V
authors.initials: AV
authors.lastname: Vazhenin
authors.forename: E A
authors.initials: EA
authors.lastname: Nadvikova
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Lukina
authors.forename: A V
authors.initials: AV
authors.lastname: Komissarov
authors.forename: E G
authors.initials: EG
authors.lastname: Zabolotskaia
mesh_terms: D000328:Adult; D000368:Aged; D019583:Dose Fractionation, Radiation; D005260:Female; D005500:Follow-Up Studies; D005720:Gamma Rays / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D015994:Incidence; D007430:Intraoperative Care / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D012509:Sarcoma / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome