title: Ni-catalyzed stereoselective arylation of inert C-O bonds at low temperatures.
abstract: A Ni-catalyzed arylation of inert C-O bonds that operates at temperatures as low as -40 °C is described. Unlike other methods for C-O bond cleavage utilizing organometallic species, this protocol operates at low temperatures, thus allowing the presence of sensitive functional groups with exquisite site-selectivity and stereoselectivity.
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ) , Av Països Catalans 16, 43007 Tarragona, Spain , and Catalan Institution for Research and Advanced Studies (ICREA) , Passeig Lluïs Companys, 23, 08010 Barcelona, Spain.
authors.forename: Josep
authors.initials: J
authors.lastname: Cornella
authors.forename: Ruben
authors.initials: R
authors.lastname: Martin
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D009532:Nickel / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D000438:Alcohols; D009942:Organometallic Compounds; D009532:Nickel