title: Clinical, pathologic, and imaging features and biological markers of uveal melanoma.
abstract: Uveal melanoma has unique clinical and pathologic features including virtually exclusive metastasis to the liver in high-risk cases. In this chapter, the clinical findings in uveal melanoma and diagnostic methods including imaging tests and serum markers are described. Additionally, the histopathologic features including the modified Callender classification and immunohistochemical findings of uveal melanoma are described.
authors.affiliation: David G. Cogan Ophthalmic Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.
authors.forename: Alia B
authors.initials: AB
authors.lastname: Rashid
authors.forename: Hans E
authors.initials: HE
authors.lastname: Grossniklaus
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood / Q000378:metabolism*; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D007150:Immunohistochemistry; D008111:Liver Function Tests; D008545:Melanoma / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D014604:Uveal Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D000098943:Uveal Melanoma
chemical_list: D014408:Biomarkers, Tumor