title: Twenty-year summary of surveillance for human hantavirus infections, United States.
abstract: In the past 20 years of surveillance for hantavirus in humans in the United States, 624 cases of hantavirus pulmonary syndrome (HPS) have been reported, 96% of which occurred in states west of the Mississippi River. Most hantavirus infections are caused by Sin Nombre virus, but cases of HPS caused by Bayou, Black Creek Canal, Monongahela, and New York viruses have been reported, and cases of domestically acquired hemorrhagic fever and renal syndrome caused by Seoul virus have also occurred. Rarely, hantavirus infections result in mild illness that does not progress to HPS. Continued testing and surveillance of clinical cases in humans will improve our understanding of the etiologic agents involved and the spectrum of diseases.
authors.forename: Barbara
authors.initials: B
authors.lastname: Knust
authors.forename: Pierre E
authors.initials: PE
authors.lastname: Rollin
mesh_terms: D062306:Geography, Medical; D006476:Orthohantavirus / Q000145:classification* / Q000235:genetics; D018778:Hantavirus Infections / Q000453:epidemiology* / Q000821:virology; D018804:Hantavirus Pulmonary Syndrome / Q000453:epidemiology; D006801:Humans; D011159:Population Surveillance; D029261:Sin Nombre virus / Q000235:genetics; D014481:United States / Q000453:epidemiology
keywords: Bayou virus; Black Creek Canal virus; Monongahela virus; New York virus; Seoul virus; Sin Nombre virus; United States; hantavirus; hantavirus pulmonary syndrome; hemorrhagic fever with renal syndrome; respiratory infections; viruses; zoonoses