title: Novel variants of clade 2.3.4 highly pathogenic avian influenza A(H5N1) viruses, China.
abstract: We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009-2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may reduce the efficacy of vaccines designed to control these viruses in poultry.
authors.forename: Min
authors.initials: M
authors.lastname: Gu
authors.forename: Guo
authors.initials: G
authors.lastname: Zhao
authors.forename: Kunkun
authors.initials: K
authors.lastname: Zhao
authors.forename: Lei
authors.initials: L
authors.lastname: Zhong
authors.forename: Junqing
authors.initials: J
authors.lastname: Huang
authors.forename: Hongquan
authors.initials: H
authors.lastname: Wan
authors.forename: Xiaoquan
authors.initials: X
authors.lastname: Wang
authors.forename: Wenbo
authors.initials: W
authors.lastname: Liu
authors.forename: Huimou
authors.initials: H
authors.lastname: Liu
authors.forename: Daxin
authors.initials: D
authors.lastname: Peng
authors.forename: Xiufan
authors.initials: X
authors.lastname: Liu
mesh_terms: D000818:Animals; D002645:Chickens; D002681:China / Q000453:epidemiology; D005838:Genotype; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000235:genetics; D053124:Influenza A Virus, H5N1 Subtype / Q000145:classification* / Q000235:genetics*; D005585:Influenza in Birds / Q000453:epidemiology* / Q000821:virology*; D010802:Phylogeny; D011200:Poultry / Q000821:virology; D011201:Poultry Diseases / Q000453:epidemiology / Q000821:virology
chemical_list: D019267:Hemagglutinin Glycoproteins, Influenza Virus
keywords: AIV; China; H5; H5N1; HPAI; avian; avian influenza virus; birds; chickens; clade; clade 2.3.4; flu; highly pathogenic; influenza; influenza virus; phylogeny; viruses