title: Evaluation of anti-hyperlipidemic activity of Lekhana Basti in albino rats.
abstract: Lekhana Basti (medicated enema) is a Tikshna formulation which is basically aimed for Apatarpana of the body. The present study (medicated enema) was undertaken to evaluate its anti-hyperlipidemic activity in diet-induced hyperlipidemia animals. Parameters like changes in body weight, organ weight, serum total cholesterol, serum triglyceride, serum HDL cholesterol, and serum (LDL + VLDL) cholesterol were studied to assess the effect of therapy in comparison to the control groups. Lekhana Basti was found to be ineffective in producing anti-hyperlipidemic action potently, but still found to have cytoprotective activity against hyperlipidemia induced organ damage, which was also confirmed by attenuation of cell infiltration and microfatty changes on histopathological examination.
authors.affiliation: Ph. D. Scholar, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India.
authors.forename: S Auti
authors.initials: SA
authors.lastname: Swapnil
authors.forename: B Thakar
authors.initials: BT
authors.lastname: Anup
authors.forename: V J
authors.initials: VJ
authors.lastname: Shukla
authors.forename: B K
authors.initials: BK
authors.lastname: Ashok
authors.forename: B
authors.initials: B
authors.lastname: Ravishankar
keywords: Apatarpana; Lekhana Basti; cholesterol; cytoprotective; hyperlipidemia