title: Pilot study to validate a computer-based clinical decision support system for dyslipidemia treatment (HTE-DLP).
abstract: Pilot study to validate a Computerized Decision Support Systems (CDS) (HTE-DLP) for improving treatment of hyperlipidemia.
  
  
  METHODS
  HTE-DLP was programmed to offer automatic specific reminders for lipid treatment. Seventy-seven patients with high cardiovascular risk were randomized. 10 expert physicians in cardiovascular-risk management were recruited. We assessed number of patients at LDL <70 mg/dl after 12 weeks of treatment.
  
  
  RESULTS
  A greater proportion of intervention group reached the LDL-C <70 mg/ml [55.0% vs 12.5%, p = 0.003; OR: 3.26 IC (1.16-9.15)]. "High potency statins" and combined therapy were used more frequently in the intervention group than the control group (p = 0.001). Seven adverse effects were documented in the intervention group and two in the control group. An acceptable relationship was observed with regard to costeffectiveness in the intervention group. Physicians expressed good agreement with HTE-DLP (86.1%) and comfortable ease-of-use (85%).
  
  
  CONCLUSIONS
  Use of a CDSS in high-risk cardiovascular patients resulted in a significant reduction in LDL-C levels.
authors.affiliation: TransLab Research Group, Medical Sciences Department, University of Girona, Catalonia, Spain; Lipid and Atherosclerosis Unit, Hospital de Blanes, Girona, Spain; Heracles Cardiovascular Network, Spain; Department of Internal Medicine, Hospital de Blanes, Girona, Spain. Electronic address: azamorac.zamora@gmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Zamora
authors.forename: F
authors.initials: F
authors.lastname: Fernández de Bobadilla
authors.forename: C
authors.initials: C
authors.lastname: Carrion
authors.forename: G
authors.initials: G
authors.lastname: Vázquez
authors.forename: G
authors.initials: G
authors.lastname: Paluzie
authors.forename: R
authors.initials: R
authors.lastname: Elosua
authors.forename: M
authors.initials: M
authors.lastname: Vilaseca
authors.forename: A
authors.initials: A
authors.lastname: Martín-Urda
authors.forename: A
authors.initials: A
authors.lastname: Rivera
authors.forename: N
authors.initials: N
authors.lastname: Plana
authors.forename: L
authors.initials: L
authors.lastname: Masana
mesh_terms: D000368:Aged; D050197:Atherosclerosis / Q000191:economics / Q000628:therapy; D002309:Cardiology / Q000379:methods / Q000592:standards; D008078:Cholesterol, LDL / Q000097:blood; D003362:Cost-Benefit Analysis; D020000:Decision Support Systems, Clinical / Q000191:economics*; D050171:Dyslipidemias / Q000191:economics / Q000628:therapy*; D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000191:economics / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood; D014584:User-Computer Interface
chemical_list: D008078:Cholesterol, LDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D014280:Triglycerides
keywords: CDSS; Computerized decision support system; Hyperlipidemia