title: [Tranexamic acid gel in patients treated with oral anticoagulants].
abstract: OBJECTIVE
  Patients treated with oral anticoagulants have increased susceptibility to bleeding, and therefore any surgical medical procedure and especially oral surgery requires a therapeutic approach that minimizes bleeding effects in these patients.
  
  
  METHODS
  The working hypothesis was based on studies of local application of tranexamic acid after maxillofacial interventions as effective therapeutic alternative for the prevention and control of bleeding. The aim was to assess the effectiveness of the application of a gel solution tranexamic acid after tooth extraction in anticoagulated patients in terms of healing time and degree of healing.
  
  
  RESULTS
  The results indicate that application of tranexamic acid gel is very effective for consistency and maintenance in the place of action and shows its efficacy as a procoagulant material.
  
  
  CONCLUSIONS
  The application of a gel solution of tranexamic acid in oral anticoagulants patients ameliorates healing time and the bleeding time within the first 48-72 h.
authors.affiliation: Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontología, Universidad Complutense de Madrid, Madrid, España. Electronic address: jorgeripolles@hotmail.com.
authors.forename: Jorge
authors.initials: J
authors.lastname: Ripollés-de Ramón
authors.affiliation: Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontología, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Marta
authors.initials: M
authors.lastname: Muñoz-Corcuera
authors.affiliation: Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontología, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Carmen
authors.initials: C
authors.lastname: Bravo-Llatas
authors.affiliation: Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontología, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Antonio
authors.initials: A
authors.lastname: Bascones-Martínez
mesh_terms: D000074:Acenocoumarol / Q000009:adverse effects* / Q000627:therapeutic use; D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D000933:Antifibrinolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005782:Gels; D006801:Humans; D019106:Postoperative Hemorrhage / Q000139:chemically induced / Q000188:drug therapy* / Q000209:etiology; D014081:Tooth Extraction; D014148:Tranexamic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D000925:Anticoagulants; D000933:Antifibrinolytic Agents; D005782:Gels; D014148:Tranexamic Acid; D000074:Acenocoumarol
keywords: Anticoagulantes orales; Dental extraction; Exodoncia; Oral anticoagulants; Tranexamic acid; Ácido tranexámico