title: Lipid profile in cerebrovascular accidents.
abstract: BACKGROUND
  Changes in the lipid profile have been suggested as a risk factor for developing ischemic stroke. Their role in intra-cerebral hemorrhage, however, is not clear. The present study was designed to evaluate the lipid profile levels of patients who had experienced an acute stroke during the first 24-hour and to compare these levels in different patients suffering from the stroke, either hemorrhagic or ischemic, and healthy individuals.
  
  
  METHODS
  In this cross-sectional study, 258 consecutive patients with acute stroke admitted to the neurology department of our center during September 2006 and September 2007 were studied. As for the control group, 187 apparently healthy subjects living in the same community and matched for age and sex were selected. Lipid profile was measured and compared between the three groups.
  
  
  RESULTS
  In the patients' group, 65 suffered from hemorrhagic stroke (group 1) and the other 193 had ischemic stroke (group 2). Except for TG values, there was no significant difference among the ischemic and hemorrhagic lipid profile. Age, cholesterol, and LDL influenced the risk of developing an ischemic stroke; TG was not reported as a risk factor or a protective one. While the comparison of data retrieved from patients suffering from hemorrhagic strokes with the controls, revealed LDL as the risk factor contributing to the development of ICH whereas TG was reported as a protective factor.
  
  
  CONCLUSIONS
  It could be concluded that LDL level can be considered as a risk factor for both ischemic and hemorrhagic cerebral events.
authors.affiliation: Neurology Department, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran ; Iranian Center of Neurological Research, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mansoureh
authors.initials: M
authors.lastname: Togha
authors.forename: Mohamad Reza
authors.initials: MR
authors.lastname: Gheini
authors.forename: Babak
authors.initials: B
authors.lastname: Ahmadi
authors.forename: Patricia
authors.initials: P
authors.lastname: Khashaiar
authors.forename: Soodeh
authors.initials: S
authors.lastname: Razeghi
keywords: Cholesterol; Intracerebral Hemorrhage; Ischemic Stroke; LDL; Stroke; Triglyceride