title: Use of silver carbonate in the Wittig reaction.
abstract: An efficient synthesis of olefins by the coupling of stabilized, semistabilized, and nonstabilized phosphorus ylides with various carbonyl compounds in the presence of silver carbonate is reported. Wittig olefination of aromatic, heteroaromatic, and aliphatic aldehydes (yields >63%) and a ketone (yield 42%) are demonstrated. These reactions proceed overnight at room temperature, under weakly basic conditions, and as such extend the applicability of the Wittig reaction to base-sensitive reactants.
authors.affiliation: Department of Chemistry and Biochemistry, University of Notre Dame , Notre Dame, Indiana 46556, United States.
authors.forename: Lukas
authors.initials: L
authors.lastname: Jedinak
authors.forename: LaToya
authors.initials: L
authors.lastname: Rush
authors.forename: Mijoon
authors.initials: M
authors.lastname: Lee
authors.forename: Dusan
authors.initials: D
authors.lastname: Hesek
authors.forename: Jed F
authors.initials: JF
authors.lastname: Fisher
authors.forename: Bill
authors.initials: B
authors.lastname: Boggess
authors.forename: Bruce C
authors.initials: BC
authors.lastname: Noll
authors.forename: Shahriar
authors.initials: S
authors.lastname: Mobashery
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D002254:Carbonates / Q000737:chemistry*; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D018030:Silver Compounds / Q000737:chemistry*
chemical_list: D000475:Alkenes; D002254:Carbonates; D018030:Silver Compounds; C033260:silver carbonate