title: Evaluation of the Ethiopian Millennium Rural Initiative: impact on mortality and cost-effectiveness.
abstract: OBJECTIVE
  Few studies have examined the long-term, impact of large-scale interventions to strengthen primary care services for women and children in rural, low-income settings. We evaluated the impact of the Ethiopian Millennium Rural Initiative (EMRI), an 18-month systems-based intervention to improve the performance of 30 primary health care units in rural areas of Ethiopia.
  
  
  METHODS
  We assessed the impact of EMRI on maternal and child survival using The Lives Saved Tool (LiST), Demography (DemProj) and AIDS Impact Model (AIM) tools in Spectrum software, inputting monthly data on 6 indicators 1) antenatal coverage (ANC), 2) skilled birth attendance coverage (SBA), 3) post-natal coverage (PNC), 4) HIV testing during ANC, 5) measles vaccination coverage, and 6) pentavalent 3 vaccination coverages. We calculated a cost-benefit ratio of the EMRI program including lives saved during implementation and lives saved during implementation and 5 year follow-up.
  
  
  RESULTS
  A total of 134 lives (all children) were estimated to have been saved due to the EMRI interventions during the 18-month intervention in 30 health centers and their catchment areas, with an estimated additional 852 lives (820 children and 2 adults) saved during the 5-year post-EMRI period. For the 18-month intervention period, EMRI cost $37,313 per life saved ($42,366 per life if evaluation costs are included). Calculated over the 18-month intervention plus 5 years post-intervention, EMRI cost $5,875 per life saved ($6,671 per life if evaluation costs are included). The cost effectiveness of EMRI improves substantially if the performance achieved during the 18 months of the EMRI intervention is sustained for 5 years. Scaling up EMRI to operate for 5 years across the 4 major regions of Ethiopia could save as many as 34,908 lives.
  
  
  CONCLUSIONS
  A systems-based approach to improving primary care in low-income settings can have transformational impact on lives saved and be cost-effective.
authors.affiliation: Yale School of Public Health and Global Health Leadership Institute, New Haven, Connecticut, United States of America.
authors.forename: Leslie A
authors.initials: LA
authors.lastname: Curry
authors.forename: Patrick
authors.initials: P
authors.lastname: Byam
authors.forename: Erika
authors.initials: E
authors.lastname: Linnander
authors.forename: Kyeen M
authors.initials: KM
authors.lastname: Andersson
authors.forename: Yigeremu
authors.initials: Y
authors.lastname: Abebe
authors.forename: Abraham
authors.initials: A
authors.lastname: Zerihun
authors.forename: Jennifer W
authors.initials: JW
authors.lastname: Thompson
authors.forename: Elizabeth H
authors.initials: EH
authors.lastname: Bradley
mesh_terms: D002648:Child; D003362:Cost-Benefit Analysis / Q000191:economics*; D005002:Ethiopia; D005260:Female; D006801:Humans; D008430:Maternal-Child Health Centers / Q000191:economics*; D009035:Mothers; D011320:Primary Health Care / Q000191:economics*; D012424:Rural Population