title: Diagnosis, nonsurgical management, and prevention of LVAD thrombosis.
abstract: Left ventricular assist device (LVAD) thrombosis is a life-threatening complication. Multiple case reports describe successful nonsurgical management with thrombolytics, aggressive antiplatelet therapy, or percutaneous catheter-directed thrombectomy. However, consensus management of LVAD thrombosis has not been established and guidelines are urgently needed. In order to raise awareness of nonsurgical treatment options, we review the current strategies for the clinical diagnosis, management, and prevention of LVAD thrombosis.
authors.affiliation: Division of Cardiovascular Surgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania.
authors.forename: Carlo R
authors.initials: CR
authors.lastname: Bartoli
authors.forename: Gorav
authors.initials: G
authors.lastname: Ailawadi
authors.forename: John A
authors.initials: JA
authors.lastname: Kern
mesh_terms: D006331:Heart Diseases / Q000175:diagnosis* / Q000517:prevention & control / Q000628:therapy*; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D017410:Practice Guidelines as Topic; D017131:Thrombectomy / Q000379:methods*; D013927:Thrombosis / Q000175:diagnosis* / Q000517:prevention & control / Q000628:therapy*
chemical_list: D010975:Platelet Aggregation Inhibitors