title: Variable immune molecules in invertebrates.
abstract: Recently it has become evident that invertebrates may mount a highly variable immune response that is dependent on which pathogen is involved. The molecular mechanisms behind this diversity are beginning to be unravelled and in several invertebrate taxa immune proteins exhibiting a broad range of diversity have been found. In some cases, evidence has been gathered suggesting that this molecular diversity translates into the ability of an affected invertebrate to mount a defence that is specifically aimed at a particular pathogen.
authors.affiliation: Department of Comparative Physiology, Uppsala University, Norbyvägen 18A, 752 36 Uppsala, Sweden.
authors.forename: Lage
authors.initials: L
authors.lastname: Cerenius
authors.forename: Kenneth
authors.initials: K
authors.lastname: Söderhäll
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D015815:Cell Adhesion Molecules / Q000737:chemistry / Q000276:immunology / Q000502:physiology; D054884:Host-Pathogen Interactions / Q000276:immunology; D007113:Immunity, Innate; D007136:Immunoglobulins / Q000737:chemistry / Q000276:immunology / Q000502:physiology; D007448:Invertebrates / Q000276:immunology* / Q000382:microbiology; D017434:Protein Structure, Tertiary; D020539:Sequence Analysis, Protein; D051193:Toll-Like Receptors / Q000737:chemistry / Q000276:immunology / Q000502:physiology
chemical_list: D015815:Cell Adhesion Molecules; D007136:Immunoglobulins; D051193:Toll-Like Receptors
keywords: Dscam; FREP; innate immunity; invertebrate immunity; recognition