title: Reversible Hypotony and Choroidal Effusion Following the Use of Pergolide for Parkinson's Disease.
abstract: OBJECTIVE
  To alert clinicians of the possibility of reversible drug-induced occult hypotony and choroidal effusion following the long-term use of pergolide.
  
  
  METHODS
  Annotations were made while the case was observed. The clinical records of the patient were reviewed retrospectively.
  
  
  RESULTS
  A 74-year-old Caucasian male with primary open-angle glaucoma presenting with reduced vision in both eyes and an inflamed right eye. Examination revealed bilateral hypotony, right anterior chamber inflammation, and right choroidal effusion. The right intraocular inflammation resolved completely after a short course of topical and oral antibiotics in addition to topical steroids. Nevertheless, the bilateral hypotony and right choroidal effusion persisted. Only the discontinuation of pergolide allowed the complete resolution of the patient's presenting symptoms and signs.
  
  
  CONCLUSIONS
  Pergolide is known to cause pericardial and pleural effusion, and generalized oedema. However, its association with choroidal effusion and hypotony has never been reported.
authors.affiliation: a Birmingham & Midland Eye Centre, Sandwell and West Birmingham Hospitals NHS Trust , Birmingham , UK .
authors.forename: Walter
authors.initials: W
authors.lastname: Andreatta
authors.affiliation: a Birmingham & Midland Eye Centre, Sandwell and West Birmingham Hospitals NHS Trust , Birmingham , UK .|b Department of Ophthalmology , University Hospitals Birmingham NHS Foundation Trust , Birmingham , UK .|c Centre for Health and Social Care Improvement, University of Wolverhampton , Wolverhampton , UK and.|d National Institute for Health Research, Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology , London , UK.
authors.forename: Peter
authors.initials: P
authors.lastname: Shah
mesh_terms: D000368:Aged; D015862:Choroid Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000503:physiopathology; D018491:Dopamine Agonists / Q000009:adverse effects*; D005902:Glaucoma, Open-Angle / Q000150:complications; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D015814:Ocular Hypotension / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000503:physiopathology; D010300:Parkinson Disease / Q000188:drug therapy*; D010479:Pergolide / Q000009:adverse effects*; D014463:Ultrasonography
chemical_list: D018491:Dopamine Agonists; D010479:Pergolide
keywords: Choroidal effusion; Parkinson’s disease; glaucoma; hypotony; pergolide