title: Some differentiating effects of selenium on the cultured human hepatoma cells and human pulmonary adenocarcinoma cells in vitro.
abstract: Two human hepatoma cell lines, QGY-7703 and SMMC-7721, and two human pulmonary adenocarcinoma cell lines, LTEP-a-2 and SPC-A-1, were found to respond to 1 μg/mL Na2SeO3, 24 h, in-vitro treatment by decreasing its confluent saturation density. The same treatment was found to cause an increase in the adhesiveness of cells measured as resistance to detachment by trypsin/EDTA. The pathological features of tumors after heterotransplantation of treated and untreated cells were similar, but the size of tumor grown from treated cells was much smaller.
authors.affiliation: Cancer Institute, Chinese Academy of Medical Sciences, Beijing, China.
authors.forename: A
authors.initials: A
authors.lastname: Pung
authors.forename: Z
authors.initials: Z
authors.lastname: Mei
authors.forename: S Y
authors.initials: SY
authors.lastname: Yu