title: Appraising failure of surgical and percutaneous revascularization: long term outcomes from an observational registry.
abstract: OBJECTIVE
  Many randomized trials have compared coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) in terms of efficacy, but data comparing outcomes of patients in which these two techniques have failed are lacking.
  
  
  METHODS
  We included patients undergoing PCI at our center between July 2002 and December 2004. Subjects were distinguished in 2 groups: those with at least one occluded or stenotic saphenous vein graft (CABG failure), and those with at least one stent with angiographically documented restenosis (PCI failure). The primary endpoint was the long-term rate of major adverse clinical events.
  
  
  RESULTS
  Two hundred and thirthy four patients were included, with a medium follow up of 61±13 months; 134 were assigned to the CABG failure group, and 104 to the PCI failure group, sharing high rates of baseline risk factors. At long term rates of death were higher in post CABG group (22.1% vs. 9.9%; P=0.015, RR 2.24 C.I. 95% 1.14-4.40) while death rates in patients with diagnosis of diabetes mellitus (24.0% vs. 23.5%; P=0.969, RR 1.020 C.I. 95% 0.38-2.74) were not different
  
  
  CONCLUSIONS
  PCI can be safely offered to both these kinds of patients: as recently demonstrated post CABG outcomes seem to be more favorable in patients with diabetes mellitus.
authors.affiliation: Division of Cardiology, University of Turin Turin, Italy - fabrizio.dascenzo@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: D'Ascenzo
authors.forename: M
authors.initials: M
authors.lastname: Bollati
authors.forename: G
authors.initials: G
authors.lastname: Quadri
authors.forename: A
authors.initials: A
authors.lastname: Gonella
authors.forename: M
authors.initials: M
authors.lastname: Di Cuia
authors.forename: V
authors.initials: V
authors.lastname: De Simone
authors.forename: C
authors.initials: C
authors.lastname: Colaci
authors.forename: C
authors.initials: C
authors.lastname: Reitano
authors.forename: M
authors.initials: M
authors.lastname: Vagnarelli
authors.forename: G
authors.initials: G
authors.lastname: Biondi Zoccai
authors.forename: C
authors.initials: C
authors.lastname: Moretti
authors.forename: F
authors.initials: F
authors.lastname: Sciuto
authors.forename: P
authors.initials: P
authors.lastname: Omedè
authors.forename: I
authors.initials: I
authors.lastname: Sheiban
authors.forename: F
authors.initials: F
authors.lastname: Gaita
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D001026:Coronary Artery Bypass / Q000379:methods*; D003327:Coronary Disease / Q000601:surgery*; D023903:Coronary Restenosis / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000379:methods*; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D015607:Stents; D013997:Time Factors; D017211:Treatment Failure; D016896:Treatment Outcome