title: Fibrin glue augmentation for flexor tendon repair increases friction compared with epitendinous suture.
abstract: OBJECTIVE
  To compare the gliding resistance, repair gapping, and ultimate strength of a common suture construct with a modified construct with fibrin glue augmentation.
  
  
  METHODS
  Twelve human cadaveric flexor digitorum profundus tendons were transected and repaired with a 4-strand core suture. Specimens were divided into 2 groups and augmented with epitendinous suture (n = 6) or fibrin glue (n = 6). We compared gliding resistance, 2-mm gapping, and ultimate strength of the repaired tendon between groups.
  
  
  RESULTS
  The linear stiffness, force to produce a 2-mm gap, and ultimate failure were similar in both repair methods. However, the 4-strand suture repair with fibrin glue augmentation displayed significantly higher gliding resistance compared with the 4-strand suture with a running epitendinous suture.
  
  
  CONCLUSIONS
  The significantly increased gliding resistance associated with fibrin glue raises questions regarding the use of this material for flexor tendon repair augmentation.
  
  
  CONCLUSIONS
  In a human cadaveric study, fibrin glue augmentation to zone II flexor tendon repairs significantly increased friction in the tendon sheath compared with an epitendinous suture.
authors.affiliation: Lecanto, FL.
authors.forename: N Michael
authors.initials: NM
authors.lastname: Xu
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Brown
authors.forename: Johannes F
authors.initials: JF
authors.lastname: Plate
authors.forename: Omar F
authors.initials: OF
authors.lastname: Nazir
authors.forename: George S
authors.initials: GS
authors.lastname: Gluck
authors.forename: Joel D
authors.initials: JD
authors.lastname: Stitzel
authors.forename: Zhongyu
authors.initials: Z
authors.lastname: Li
mesh_terms: D001696:Biomechanical Phenomena; D002102:Cadaver; D019245:Compressive Strength; D015718:Fibrin Tissue Adhesive / Q000494:pharmacology*; D005385:Fingers / Q000601:surgery; D017276:Friction; D006801:Humans; D019651:Plastic Surgery Procedures / Q000379:methods*; D013314:Stress, Mechanical; D013536:Suture Techniques; D013708:Tendon Injuries / Q000601:surgery*; D013710:Tendons / Q000601:surgery
chemical_list: D015718:Fibrin Tissue Adhesive