title: Statistical design and evaluation of biomarker studies.
abstract: We review biostatistical aspects of biomarker studies, including design and analysis issues, covering the range of settings required for translational research-from early exploratory studies through clinical trials.
authors.affiliation: Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, USA.
authors.forename: Kevin K
authors.initials: KK
authors.lastname: Dobbin
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis*; D002460:Cell Line; D002986:Clinical Trials as Topic; D006801:Humans; D012189:Retrospective Studies; D013223:Statistics as Topic / Q000379:methods*
chemical_list: D014408:Biomarkers, Tumor