title: Glufosinate herbicide intoxication causing unconsciousness, convulsion, and 6th cranial nerve palsy.
abstract: Although glufosinate ammonium herbicides are considered safe when used properly, ingestion of the undiluted form can cause grave outcomes. Recently, we treated a 34-yr-old man who ingested glufosinate ammonium herbicide. In the course of treatment, the patient developed apnea, mental deterioration, and sixth cranial nerve palsy; he has since been discharged with full recovery after intensive care. This case report describes the clinical features of glufosinate intoxication with a focus on sixth cranial nerve palsy. Our observation suggests that neurologic manifestations after ingestion of a "low-grade toxicity herbicide" are variable and more complex than that was previously considered.
authors.affiliation: Department of Internal Medicine, Soonchunhyang University, College of Medicine, Cheonan, Korea.
authors.forename: Jae-seok
authors.initials: JS
authors.lastname: Park
authors.forename: Soo-Jung
authors.initials: SJ
authors.lastname: Kwak
authors.forename: Hyo-wook
authors.initials: HW
authors.lastname: Gil
authors.forename: So-Young
authors.initials: SY
authors.lastname: Kim
authors.forename: Sae-yong
authors.initials: SY
authors.lastname: Hong
mesh_terms: D020434:Abducens Nerve Diseases / Q000139:chemically induced* / Q000188:drug therapy; D000328:Adult; D000613:Aminobutyrates / Q000506:poisoning*; D004791:Enzyme Inhibitors / Q000506:poisoning; D006540:Herbicides / Q000506:poisoning*; D006801:Humans; D008297:Male; D012640:Seizures / Q000139:chemically induced; D013501:Surface-Active Agents / Q000506:poisoning; D014474:Unconsciousness / Q000139:chemically induced
chemical_list: D000613:Aminobutyrates; D004791:Enzyme Inhibitors; D006540:Herbicides; D013501:Surface-Active Agents; C003121:phosphinothricin
keywords: Abducens Nerve Disease; Glufosinate Ammonium; Neurologic Manifestations