title: Evidence that steric factors modulate reactivity of tautomeric iron-oxo species in stereospecific alkane C-H hydroxylation.
abstract: A new iron complex mediates stereospecific hydroxylation of alkyl C-H bonds with hydrogen peroxide, exhibiting excellent efficiency. Isotope labelling studies provide evidence that the relative reactivity of tautomerically related oxo-iron species responsible for the C-H hydroxylation reaction is dominated by steric factors.
authors.affiliation: Chemical Physics, Department of Chemistry, Lund University, P.O. Box 124, Lund, SE-221 00, Sweden. Ebbe.Nordlander@chemphys.lu.se.
authors.forename: Mainak
authors.initials: M
authors.lastname: Mitra
authors.forename: Julio
authors.initials: J
authors.lastname: Lloret-Fillol
authors.forename: Matti
authors.initials: M
authors.lastname: Haukka
authors.forename: Miquel
authors.initials: M
authors.lastname: Costas
authors.forename: Ebbe
authors.initials: E
authors.lastname: Nordlander
mesh_terms: D000473:Alkanes / Q000737:chemistry*; D056831:Coordination Complexes / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry; D006900:Hydroxylation; D007501:Iron / Q000737:chemistry*; D015394:Molecular Structure; D010105:Oxygenases / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000473:Alkanes; D056831:Coordination Complexes; D006861:Hydrogen Peroxide; D007501:Iron; D010105:Oxygenases