title: Failure of siblings to thrive beyond 5 years of age.
abstract: We describe a family in which parents had consanguinity, being children of real sisters. They had given birth to five children. In their family, children remained healthy from birth to pre-school age and then started having symptoms around the age of 5 years and two of them succumbed to this illness. Polyglandular autoimmune syndrome Type-1 is a rare sporadic autosomal recessive disease. It is characterized by the existence of two or more endocrinal disorders. Patients may require lifelong hormone replacement therapy for survival.
authors.affiliation: Department of Medicine, Peoples College of Medical Sciences and Research Centre, Bhanpur, Bhopal, Madhya Pradesh, India.
authors.forename: Himanshu
authors.initials: H
authors.lastname: Jain
authors.forename: Vivek
authors.initials: V
authors.lastname: Saxena
authors.forename: Sushil
authors.initials: S
authors.lastname: Jindal
authors.forename: Shaifali
authors.initials: S
authors.lastname: Bansal
keywords: Autoimmune; hypoparathyroidism; moniliasis; polyglandular; primary adrenal insufficiency