title: A rare collision tumor of squamous carcinoma and small cell carcinoma in esophagus involved with separate lymph nodes: a case report.
abstract: We report a case of an esophageal collision tumor composed of squamous cell carcinoma and small cell carcinoma (SmCC). A 66-year-old man complained of chest pain after oral intake for nearly one month. The patient received two cycles of neoadjuvant platinum-based combination chemotherapy and enhanced computed tomography showed a partial response of the tumor. He then underwent a thoracolaparoscopic esophagectomy with extensive mediastinal lymphadenectomy. Two cycles of chemotherapy and prophylactic irradiation of the lymphatic drainage region were sequentially achieved after surgery. The patient has survived for more than 18 months with no evidence of recurrent disease since surgical resection.
authors.affiliation: Department of Thoracic Surgery, Zhongshan Hospital of Fudan University, Shanghai 200032, China.
authors.forename: Jingpei
authors.initials: J
authors.lastname: Li
authors.forename: Xiaoke
authors.initials: X
authors.lastname: Chen
authors.forename: Yaxing
authors.initials: Y
authors.lastname: Shen
authors.forename: Yingyong
authors.initials: Y
authors.lastname: Hou
authors.forename: Shumin
authors.initials: S
authors.lastname: Zhang
authors.forename: Hao
authors.initials: H
authors.lastname: Wang
authors.forename: Mingxiang
authors.initials: M
authors.lastname: Feng
authors.forename: Lijie
authors.initials: L
authors.lastname: Tan
authors.forename: Qun
authors.initials: Q
authors.lastname: Wang
authors.forename: Zhaochong
authors.initials: Z
authors.lastname: Zeng
keywords: Esophageal cancer; collision tumor; small cell carcinoma; squamous cell carcinoma