title: [Comparing hydroxyapatite coated versus non hydroxyapatite coated femoral stems in primary total hip arthroplasty: a meta analysis of randomized controlled trial].
abstract: OBJECTIVE
  To evaluate the difference of clinical outcomes and radiological outcomes through meta-analysis on the total hip arthroplasty (THA) between hydroxyapatite(HA) coating and non-HA coating femoral stems.
  
  
  METHODS
  We searched the MEDLINE, Embase, Cochrane library and CBM for published randomized controlled trial (RCT) comparing HA coating and non-HA coating femoral stems in primary THA clinical outcomes with Harris hip score and incidence postoperative thigh pain, radiological outcomes with presence of endosteal condensation and radioactive line on the prothesis, heterotopic ossification. Data analysis were performed using RevMan 5.0(the Cochrane Collaboration).
  
  
  RESULTS
  Ten studies and 917 hips into our analysis, with 464 hips in HA groups and 453 hips in non-HA groups. The combined results of the meta-analysis indicated there was no statistical differences between the two groups on postoperative Harris hip score(WMD = 3.04, 95%CI:-4.47-10.54, P = 0.43) , there was statistical difference on incidence postoperative thigh pain (RR = 0.56, 95%CI:0.33-0.94, P = 0.03) . There were no significant differences between the two groups on presence of endosteal condensation (RR = 1.01, 95%CI:0.91-1.11, P = 0.91), presence of radioactive line (RR = 0.99, 95%CI:0.88-1.11, P = 0.83) and incidence of heterotopic ossification (RR = 0.97, 95%CI:0.77-1.21, P = 0.77).
  
  
  CONCLUSIONS
  There are no clinical and radiological benefits in the use of HA coating femoral stems in Primary THA, there is not enough evidence prove the HA can reduce the incidence postoperative thigh pain.
authors.affiliation: Department of Orthopedic Surgery, the Affiliated Ruikang Hospital of Guangxi Traditional Chinese Medical College, Nanning 530011, China.
authors.forename: Shu-zhen
authors.initials: SZ
authors.lastname: Li
authors.forename: Zong-han
authors.initials: ZH
authors.lastname: Lin
authors.forename: Yue-ping
authors.initials: YP
authors.lastname: Chen
authors.forename: Hui
authors.initials: H
authors.lastname: Gao
authors.forename: Wei
authors.initials: W
authors.lastname: Cui
authors.forename: Qie
authors.initials: Q
authors.lastname: Fan
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000295:instrumentation*; D020099:Coated Materials, Biocompatible; D017886:Durapatite; D005269:Femur; D006622:Hip Prosthesis; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
chemical_list: D020099:Coated Materials, Biocompatible; D017886:Durapatite