title: Enhanced depth imaging optical coherence tomography features of choroidal osteoma.
abstract: OBJECTIVE
  To describe the choroidal findings in eyes affected by choroidal osteoma imaged by enhanced depth imaging optical coherence tomography.
  
  
  METHODS
  Retrospective case series.
  
  
  RESULTS
  Seven eyes from five patients with choroidal osteoma were included in the study. Patients mean age of presentation was 26 years (median, 34; range, 6-37 years) and mean best-corrected visual acuity was 20/32 (median, 20/20; range, 20/20-20/200). Enhanced depth imaging optical coherence tomography examination revealed normal inner retina in all the cases and normal outer retina in three eyes. Abnormalities included irregularities in external limiting membrane (n = 2), myoid zone (n = 1), ellipsoid junction (n = 4), cone outer segments of photoreceptors (n = 5), and retinal pigment epithelium (n = 3). Choroidal analysis revealed thinned (n = 4) or non visible (n = 2) choriocapillaris, thinned (n = 3) or non visible (n = 4) medium vessels, and thinned large vessels layer (n = 4). The osteoma showed multiple intralesional layers (n = 5), a sponge-like appearance (n = 7), and intralesional vessels (n = 7). The sclero-choroidal junction was visible in all cases. Choroidal neovascularization was found in four eyes.
  
  
  CONCLUSIONS
  Analysis of eyes affected by choroidal osteoma revealed a characteristic sponge-like tumor appearance with the presence of multiple intralesional layers. The lesion showed a typical transparency with visibility of sclero-choroidal junction in all cases.
authors.affiliation: Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Pellegrini
authors.forename: Alessandro
authors.initials: A
authors.lastname: Invernizzi
authors.forename: Andrea
authors.initials: A
authors.lastname: Giani
authors.forename: Giovanni
authors.initials: G
authors.lastname: Staurenghi
mesh_terms: D000293:Adolescent; D000328:Adult; D002114:Calcinosis / Q000175:diagnosis*; D002648:Child; D002828:Choristoma / Q000175:diagnosis*; D015862:Choroid Diseases / Q000175:diagnosis*; D020256:Choroidal Neovascularization / Q000175:diagnosis*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D010016:Osteoma; D012164:Retinal Diseases / Q000175:diagnosis*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult