title: Endocrine management of male subfertility.
abstract: Infertility in a couple is defined as failure to conceive after 12 months of regular unprotected intercourses. Male infertility due to impaired spermatogenesis may result from hypothalamic, pituitary or testicular disorders. Medical management of infertility associated with gonadotropin deficiencies have high success rate, but for primary testicular failure assisted reproduction techniques (ART) with adjunctive endocrine manipulation remains the best therapeutic option. This article discusses various therapeutic options and regimes using gonadotropins, anti-estrgens, aromatase inhibitors in management of male subfertiltiy.
authors.affiliation: Department of Endocrinology, St. Johns Medical College Hospital, Bangalore, Karnataka, India.
authors.forename: Belinda
authors.initials: B
authors.lastname: George
authors.forename: Ganapathi
authors.initials: G
authors.lastname: Bantwal
keywords: Hypogonadotropic hypogonadism; male subfertiltiy; oligo-azoospermia