title: Therapeutic proteins: A to Z.
abstract: In recent years, therapeutic proteins have become an important growing class of drugs in the pharmaceutics industry. The development of recombinant DNA technology has caused to appreciation of therapeutic value of many proteins and peptides in medicine. Currently, approximately 100 therapeutic proteins obtained approval from Food and Drug Administration (FDA) and they are widely used in the treatment of various diseases such as cancer, diabetes, anemia and infections. This paper will summarize the production processes, pharmaceuticals and physicochemical properties and important classes of therapeutic proteins with their potential use in clinical applications.
authors.affiliation: Department of Biochemistry, Faculty of Pharmacy, Cumhuriyet University, Sivas, Turkey. ytutar@cumhuriyet.edu.tr.
authors.forename: Aykut
authors.initials: A
authors.lastname: Ozgur
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Tutar
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D016466:CHO Cells; D002460:Cell Line; D003412:Cricetulus; D004921:Erythropoietin; D004926:Escherichia coli; D006801:Humans; D007328:Insulin; D007372:Interferons; D051379:Mice; D015202:Protein Engineering; D011994:Recombinant Proteins; D012441:Saccharomyces cerevisiae
chemical_list: D000911:Antibodies, Monoclonal; D007328:Insulin; D011994:Recombinant Proteins; D004921:Erythropoietin; D007372:Interferons