title: A case of dermatomyositis with rhabdomyolysis, rescued by intravenous immunoglobulin.
abstract: We describe a case of severe dermatomyositis (DM) complicated by rhabdomyolysis, acute tubular necrosis, and hemophagocytosis. The case failed to respond to corticosteroids, but showed rapid and significant improvement after the addition of intravenous immunoglobulin (IVIG). While the prognosis of DM is poor when it is complicated by rhabdomyolysis, the early administration of IVIG has the potential to be the cornerstone of its management.
authors.affiliation: Department of Medicine and Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University , Tokyo , Japan.
authors.forename: Fumitaka
authors.initials: F
authors.lastname: Mizoguchi
authors.forename: Kazuki
authors.initials: K
authors.lastname: Takada
authors.forename: Kinya
authors.initials: K
authors.lastname: Ishikawa
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Mizusawa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kohsaka
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Miyasaka
mesh_terms: D001706:Biopsy; D003882:Dermatomyositis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D007155:Immunologic Factors / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D012206:Rhabdomyolysis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors
keywords: Dermatomyositis; Hemophagocytosis; IVIG; Rhabdomyolysis