title: Effect of high pressurization versus normal pressurization on changes in intraocular pressure immediately after clear corneal cataract surgery.
abstract: OBJECTIVE
  To compare changes in intraocular pressure (IOP) immediately after clear corneal incision (CCI) cataract surgery between eyes in which IOP was adjusted to a high or normal range at the conclusion of surgery.
  
  
  METHODS
  Hayashi Eye Hospital, Fukuoka, Japan.
  
  
  METHODS
  Comparative case series.
  
  
  METHODS
  Either eye of patients scheduled for phacoemulsification was randomized to 1 of 2 groups as follows: eyes that were to be adjusted to (1) high IOP (22 to 40 mm Hg) or (2) normal IOP (10 to 21 mm Hg). The IOP was measured using a rebound tonometer preoperatively; at the conclusion of surgery; and 15, 30, 60, 120, and 180 minutes and 24 hours postoperatively. The Seidel test and anterior segment optical coherence tomography (AS-OCT) were performed.
  
  
  RESULTS
  The mean IOP at the conclusion of surgery was 31.3 mm Hg in the high IOP group and 17.1 mm Hg in the normal IOP group. The IOP decreased to approximately 15 mm Hg by 15 minutes and did not change until 60 minutes in either group. The mean IOP did not differ significantly between groups throughout the observation period (P ≥.0634). Hypotony of 5 mm Hg or less was not detected in any eye. The Seidel test was negative and based on AS-OCT, the wound was closed at 60 minutes in all eyes.
  
  
  CONCLUSIONS
  After adjusting IOP to a high or normal range, the IOP normalized within 15 minutes postoperatively and was stable for 24 hours. The wound was closed within 60 minutes postoperatively.
authors.affiliation: From Hayashi Eye Hospital, Fukuoka, Japan. Electronic address: hayashi-ken@hayashi.or.jp.
authors.forename: Ken
authors.initials: K
authors.lastname: Hayashi
authors.affiliation: From Hayashi Eye Hospital, Fukuoka, Japan.
authors.forename: Motoaki
authors.initials: M
authors.lastname: Yoshida
authors.affiliation: From Hayashi Eye Hospital, Fukuoka, Japan.
authors.forename: Shin-Ichi
authors.initials: S
authors.lastname: Manabe
authors.affiliation: From Hayashi Eye Hospital, Fukuoka, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Yoshimura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea / Q000601:surgery*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000503:physiopathology*; D018918:Phacoemulsification; D016683:Supine Position; D041623:Tomography, Optical Coherence; D014065:Tonometry, Ocular; D014945:Wound Healing / Q000502:physiology