title: Emerging biomedicines based on bacteriophages.
abstract: Bacteriophage is bacterial virus widespread in the biosphere. Bacteriophages and their encoded endolysin (or lysin), holin, and other small proteins are intensively pursed as novel therapeutic agents to complement and tackle the increasing antibiotics resistance. Moreover, the delivery system based on bacteriophage and the diagnostic method based on engineered bacteriophage were also promising new avenues to drug delivery and diagnosis.
authors.affiliation: Institute of Modern Biopharmaceuticals, State Key Laboratory Breeding Base of Eco-Environment and Bio-Resource of the Three Gorges Area, School of Life Sciences, Southwest University, Beibei, Chongqing 400715, China.
authors.forename: Jianlong
authors.initials: J
authors.lastname: Yan
authors.forename: Xiangyu
authors.initials: X
authors.lastname: Fan
authors.forename: Jianping
authors.initials: J
authors.lastname: Xie
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects / Q000821:virology; D001435:Bacteriophages / Q000235:genetics* / Q000378:metabolism*; D016503:Drug Delivery Systems; D055808:Drug Discovery; D005818:Genetic Engineering; D014764:Viral Proteins / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D014764:Viral Proteins