title: A case of androgen-secreting adrenal carcinoma with non-classical congenital adrenal hyperplasia.
abstract: Androgen excess is one of the most common and disturbing endocrine disorder of reproductive-aged women, affecting approximately 7% of this population Androgen excess results in the development of androgenic features in the women affected, with the development of hirsutism, androgenic alopecia, ovulatory dysfunction, and, if extreme, even virilization and masculinization. Adrenocortical carcinoma (ACC) is a rare malignancy accounting for 0.02% of all annual cancers reported. About 60% are functional tumors secreting hormones, with its consequent clinical manifestations, the Cushing's syndrome due to cortisone, virilization due to androgens, feminization due to estrogens, or hypertension due to aldosterone. Adrenal tumors that secrete androgens exclusively are extremely rare. Here, we present a rare case of androgen-secreting adrenocortical carcinoma with non-classical congenital adrenal hyperplasia.
authors.affiliation: Department of Endocrinology, Sir Ganga Ram Hospital, New Delhi, India.
authors.forename: Tarun
authors.initials: T
authors.lastname: Varma
authors.forename: Roopal
authors.initials: R
authors.lastname: Panchani
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Goyal
authors.forename: Robin
authors.initials: R
authors.lastname: Maskey
keywords: Adrenocortical carcinoma; hirsutism; non classical congenital adrenal hyperplasia