title: Organic electron donors as powerful single-electron reducing agents in organic synthesis.
abstract: One-electron reduction is commonly used in organic chemistry for the formation of radicals by the stepwise transfer of one or two electrons from a donor to an organic substrate. Besides metallic reagents, single-electron reducers based on neutral organic molecules have emerged as an attractive novel source of reducing electrons. The past 20 years have seen the blossoming of a particular class of organic reducing agents, the electron-rich olefins, and their application in organic synthesis. This Review gives an overview of the different types of organic donors and their specific characteristics in organic transformations.
authors.affiliation: Aix-Marseille Université, CNRS, ICR UMR 7273, Faculty of Pharmacy, 27 Bd Jean Moulin, 13385, Marseille (France). julie.broggi@univ-amu.fr.
authors.forename: Julie
authors.initials: J
authors.lastname: Broggi
authors.forename: Thierry
authors.initials: T
authors.lastname: Terme
authors.forename: Patrice
authors.initials: P
authors.lastname: Vanelle
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis / Q000737:chemistry*; D001372:Aza Compounds / Q000138:chemical synthesis / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D004579:Electron Transport; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis / Q000737:chemistry; D048289:Imidazolidines / Q000138:chemical synthesis / Q000737:chemistry; D008956:Models, Chemical; D015394:Molecular Structure
chemical_list: D000475:Alkenes; D001372:Aza Compounds; D006571:Heterocyclic Compounds; D006845:Hydrocarbons, Fluorinated; D048289:Imidazolidines; C063887:tetrathiafulvalene
keywords: electron transfer; electron-rich olefins; organic electron donors; reduction