title: Surgical device therapy for heart failure in the adult with congenital heart disease.
abstract: Individuals with adult congenital heart disease (ACHD) are at a great risk for heart failure, and the underlying anatomic features are important predictors of heart failure. As the ACHD population grows older, multiple events, including years of an altered physiology, the neurohormonal cascade, and many still unknown, culminate in ventricular failure. Surgical device therapy is an effective method in supporting patients with heart failure. Ventricular assist devices have been used with success in bridging ACHD patients to heart transplantation or destination therapy.
authors.affiliation: Texas Children's Hospital, Pediatric Cardiology, 6621 Fannin Street, Houston, TX 77030, USA. Electronic address: vmulukut@bcm.edu.
authors.forename: Venkatachalam
authors.initials: V
authors.lastname: Mulukutla
authors.forename: Wayne J
authors.initials: WJ
authors.lastname: Franklin
authors.forename: Chet R
authors.initials: CR
authors.lastname: Villa
authors.forename: David Luís Simón
authors.initials: DL
authors.lastname: Morales
mesh_terms: D000328:Adult; D057186:Comparative Effectiveness Research; D006330:Heart Defects, Congenital / Q000145:classification / Q000150:complications / Q000378:metabolism / Q000503:physiopathology / Q000601:surgery*; D006333:Heart Failure / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology / Q000601:surgery*; D006352:Heart Ventricles / Q000473:pathology / Q000503:physiopathology; D006353:Heart-Assist Devices / Q000145:classification / Q000592:standards / Q000639:trends; D006801:Humans; D018377:Neurotransmitter Agents / Q000378:metabolism; D017063:Outcome Assessment, Health Care; D018754:Ventricular Dysfunction / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*
chemical_list: D018377:Neurotransmitter Agents
keywords: Adult congenital heart disease; Heart failure; Systemic right ventricle; Ventricular assist device