title: The minimal clinically important difference in the Oxford knee score and Short Form 12 score after total knee arthroplasty.
abstract: OBJECTIVE
  The aim of this study was to identify the minimal clinically important difference (MCID) in the Oxford knee score (OKS) and Short Form (SF-) 12 score after total knee arthroplasty (TKA).
  
  
  METHODS
  Prospective pre-operative and 1 year post-operative OKS and SF-12 scores for 505 patients undergoing a primary TKA for osteoarthritis were collected during a one-year period. Patient satisfaction with their (1) patient relief and (2) functional outcome was used as the anchor questions. Their response to each question was recorded using a 5-point Likert scale: excellent, very well, well, fair, and poor. Simple linear regression was used to calculate the MCID for improvement in the OKS and physical component of the SF-12 score according to the level of patient satisfaction with their pain relief and function.
  
  
  RESULTS
  The OKS improved by 15.5 (95 % CI 14.7-16.4) points and the SF-12 physical component score improved by 10.1 (95 % CI 9.1-11.2) points for the study cohort. The level of patient satisfaction with their pain relief and function correlated with the improvement in the OKS (r = 0.56; p < 0.001, and r = 0.56; p < 0.001) and the physical component of the SF-12 score (r = 0.51; p < 0.001, and r = 0.60; p < 0.001), respectively. The MCID for the OKS was 5.0 (95 % CI 4.4-5.5) and 4.3 (95 % CI 3.8-4.8) points and for the physical component of the SF-12, it was 4.5 (95 % CI 3.9-5.2) and 4.8 (95 % CI 4.2-5.4) points for pain relief and function, respectively.
  
  
  CONCLUSIONS
  The MCID identified for the OKS and SF-12 physical component score after TKA is the best available estimate and can be used to power studies and ensure that a statistical difference is also recognised by a patient.
authors.affiliation: Royal Infirmary of Edinburgh, Little France, Edinburgh, EH16 4SA, UK, nickclement@doctors.org.uk.
authors.forename: N D
authors.initials: ND
authors.lastname: Clement
authors.forename: D
authors.initials: D
authors.lastname: MacDonald
authors.forename: A H R W
authors.initials: AH
authors.lastname: Simpson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee; D015331:Cohort Studies; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery*; D017060:Patient Satisfaction; D011184:Postoperative Period; D011446:Prospective Studies; D020127:Recovery of Function