title: Double translocation: an interesting family history.
abstract: Double balanced translocations are particularly rare and the risk of a fetus with an unbalanced chromosomal anomaly is greater than for single translocation carriers. In this present case, we describe an interesting family history which included three generations. A couple, married for 4 years, was referred to the genetic clinic due to infertility and family chromosome anomalies. A GTG-band chromosome analysis indicated that the male partner's karyotype was 45,XY, t(3;18)(q11;ptel)t(13;14)(q10;q10). The same double balanced translocation was found in two others family members.
authors.affiliation: Department of Obstetrics and Gynecology, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Uysal
authors.forename: A
authors.initials: A
authors.lastname: Uludağ
authors.forename: F
authors.initials: F
authors.lastname: Sılan
authors.forename: N
authors.initials: N
authors.lastname: Erçelen
authors.forename: C
authors.initials: C
authors.lastname: Zafer
authors.forename: O
authors.initials: O
authors.lastname: Ozdemir
keywords: Double translocation; Fluorescent  in situ  hybridization (FISH); Miscarriage; Robertsonian translocation