title: Statin therapy for primary prevention of cardiovascular disease.
abstract: OBJECTIVE
  Do statins reduce rates of cardiovascular events when used for primary prevention?
  
  
  CONCLUSIONS
  When used for primary prevention, statins are associated with lower rates of all-cause mortality, major vascular events, and revascularizations compared with placebo. Statin therapy is not associated with increased rates of life-threatening adverse effects such as cancer.
authors.affiliation: Department of Noncommunicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
authors.forename: Fiona C
authors.initials: FC
authors.lastname: Taylor
authors.forename: Mark
authors.initials: M
authors.lastname: Huffman
authors.forename: Shah
authors.initials: S
authors.lastname: Ebrahim
mesh_terms: D002318:Cardiovascular Diseases / Q000401:mortality / Q000517:prevention & control*; D019317:Evidence-Based Medicine; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D009369:Neoplasms / Q000453:epidemiology; D011322:Primary Prevention; D016032:Randomized Controlled Trials as Topic; D012306:Risk
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors