title: Response to Diaz and de Leon "the mathematics of drug dose individualization should be built with random effects linear models".
authors.affiliation: *University of Auckland, Department of Pharmacology & Clinical Pharmacology, Auckland, New Zealand; and †University Hospital Center, Division of Clinical Pharmacology and Toxicology, Lausanne, Switzerland.
authors.forename: Nicholas H G
authors.initials: NH
authors.lastname: Holford
authors.forename: Thierry
authors.initials: T
authors.lastname: Buclin
mesh_terms: D004305:Dose-Response Relationship, Drug; D016903:Drug Monitoring / Q000379:methods*; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*; D057285:Precision Medicine / Q000379:methods*
chemical_list: D004364:Pharmaceutical Preparations