title: Correlation of total salivary secretory immunoglobulin A (SIgA) and mutans specific SIgA in children having different caries status.
abstract: BACKGROUND
  Relation between secretory immunoglobulin A (SigA) and dental caries still imprecise. Studies have been conducted either for total SIgA or mutans specific SIgA with bizarre results.
  
  
  OBJECTIVE
  The aim of this study is to find out the relationship between mutans antigen specific SIgA and total salivary SIgA and its influence in caries status in children.
  
  
  METHODS
  A total of 45 children aged between 6-14 years were divided based on their caries index (decayed, missing, filled, extracted tooth) score in high moderate and no caries group and their saliva were analyzed with enzyme linked immunosorbent assay for total SIgA and mutans specific SIgA.
  
  
  RESULTS
  High caries group showed high mutans specific SIgA, but less total SIgA, whereas low caries group showed the reverse.
  
  
  CONCLUSIONS
  The mutans specific SIgA and total SIgA has a weak, but negative correlation in children potentiating caries inhibitory action of SIgA.
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India.
authors.forename: Soumen
authors.initials: S
authors.lastname: Pal
authors.forename: Malay
authors.initials: M
authors.lastname: Mitra
authors.forename: Jiban
authors.initials: J
authors.lastname: Mishra
authors.forename: Subrata
authors.initials: S
authors.lastname: Saha
authors.forename: Bhaswar
authors.initials: B
authors.lastname: Bhattacharya
mesh_terms: D000293:Adolescent; D002648:Child; D003430:Cross-Sectional Studies; D003731:Dental Caries / Q000276:immunology* / Q000382:microbiology; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000276:immunology*; D012463:Saliva / Q000276:immunology*; D013295:Streptococcus mutans / Q000276:immunology* / Q000302:isolation & purification
chemical_list: D007071:Immunoglobulin A, Secretory