title: The role of diet and nutritional intervention for the management of patients with NAFLD.
abstract: During the last few decades, the prevalence of obesity, insulin resistance and non-alcoholic fatty liver disease (NAFLD) have dramatically increased. Nutrition and modern lifestyle habits are intimately involved in this epidemiological change. Although lifestyle intervention can theoretically revert the metabolic disturbances and prevent the long term complications of NAFLD, its efficacy is diminished in clinical practice by poor implementation and reduced adherence to lifestyle intervention programs. In this article we summarize the main elements of dietary interventions for NAFLD, describe practical strategies to optimize efficacy and review potential nutritional strategies under development that hopefully will improve outcomes in the future.
authors.affiliation: Storr Liver Unit, Westmead Millennium Institute, Westmead Hospital, University of Sydney, Darcy Road, Westmead, New South Wales 2145, Australia; Department of Gastroenterology, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago 8330024, Chile.
authors.forename: Francisco
authors.initials: F
authors.lastname: Barrera
authors.forename: Jacob
authors.initials: J
authors.lastname: George
mesh_terms: D002986:Clinical Trials as Topic; D004038:Diet, Reducing; D005234:Fatty Liver / Q000178:diet therapy* / Q000209:etiology / Q000473:pathology; D006801:Humans; D007333:Insulin Resistance; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism / Q000473:pathology; D065626:Non-alcoholic Fatty Liver Disease; D009747:Nutritional Physiological Phenomena; D009765:Obesity / Q000150:complications; D010349:Patient Compliance
keywords: Insulin resistance; Lifestyle intervention; Macronutrients; Mediterranean diet; Nonalcoholic fatty liver; Steatohepatitis; Weight loss