title: Radiation dose associated with cerebral CT angiography and CT perfusion: an experimental phantom study.
abstract: A study on the radiation dose associated with cerebral CT angiography (CTA) and CT perfusion (CTP) was conducted on an anthropomorphic phantom with the aim of estimating the effective dose (E) and entrance skin dose (ESD) in the eyes and thyroid gland during different CTA and CTP protocols. The E was calculated to be 0.61 and 0.28 mSv in CTA with 100 and 80 kV(p), respectively. In contrast, CTP resulted in an estimated E of 2.74 and 2.07 mSv corresponding to 40 and 30 s protocols, respectively. The eyes received a higher ESD than the thyroid gland in all of these protocols. The results of this study indicate that combining both CTA and CTP procedures are not recommended in the stroke evaluation due to high radiation dose. Application of modified techniques in CTA (80 kV(p)) and CTP (30 s) is highly recommended in clinical practice for further radiation dose reduction.
authors.affiliation: Diagnostic Imaging and Radiotherapy Program, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia akmal.sabarudin@fsk.ukm.my.
authors.forename: Akmal
authors.initials: A
authors.lastname: Sabarudin
authors.affiliation: Diagnostic Imaging and Radiotherapy Program, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
authors.forename: Mohd Zaki
authors.initials: MZ
authors.lastname: Yusof
authors.affiliation: Diagnostic Imaging and Radiotherapy Program, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
authors.forename: Mazlyfarina
authors.initials: M
authors.lastname: Mohamad
authors.affiliation: Discipline of Medical Imaging, Department of Imaging and Applied Physics, Curtin University, GPO Box U1987 Perth, WA 6845, Australia.
authors.forename: Zhonghua
authors.initials: Z
authors.lastname: Sun
mesh_terms: D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging* / Q000528:radiation effects; D002533:Cerebral Angiography / Q000379:methods*; D005260:Female; D006801:Humans; D010477:Perfusion; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D012867:Skin / Q000000981:diagnostic imaging* / Q000528:radiation effects; D020521:Stroke / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*