title: Neutralization of the antimicrobial effect of glyphosate by humic acid in vitro.
abstract: In the present study, the neutralization ability of the antimicrobial effect of glyphosate by different humic acids was investigated. The minimal inhibitory concentrations of glyphosate for different bacteria such as Bacillus badius, Bifidobacterium adolescentis, Escherichia coli, E. coli 1917 strain Nissle, Enterococcus faecalis, Enterococcus faecium, Salmonella enteritidis and Salmonella typhimurium were determined in the presence or absence of different concentrations of humic acid (0.25, 0.5 and 1.0 mg mL(-1)). Our findings indicated that humic acids inhibited the antimicrobial effect of glyphosate on different bacteria. This information can help overcome the negative impact of glyphosate residues in feed and water.
authors.affiliation: Institute of Bacteriology and Mycology, Faculty of Veterinary Medicine, Leipzig University, An den Tierkliniken 29, 04103 Leipzig, Germany; Albrecht Daniel Thaer-Institute of Agronomy at the University Leipzig, Gustav-Kuhn Straße 8, 04159 Leipzig, Germany; Avian and Rabbit Diseases Department, Faculty of Veterinary Medicine, Sadat City University, Egypt. Electronic address: shehata@vetmed.uni-leipzig.de.
authors.forename: Awad A
authors.initials: AA
authors.lastname: Shehata
authors.affiliation: WHPharmawerk Weinböhla GmbH, Poststr. 58, 01689 Weinböhla, Germany.
authors.forename: Manfred
authors.initials: M
authors.lastname: Kühnert
authors.affiliation: WHPharmawerk Weinböhla GmbH, Poststr. 58, 01689 Weinböhla, Germany.
authors.forename: Svent
authors.initials: S
authors.lastname: Haufe
authors.affiliation: Institute of Bacteriology and Mycology, Faculty of Veterinary Medicine, Leipzig University, An den Tierkliniken 29, 04103 Leipzig, Germany.
authors.forename: Monika
authors.initials: M
authors.lastname: Krüger
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D005998:Glycine / Q000031:analogs & derivatives* / Q000494:pharmacology; D006812:Humic Substances / Q000032:analysis*; D008826:Microbial Sensitivity Tests; D000097797:Glyphosate
chemical_list: D000890:Anti-Infective Agents; D005998:Glycine; D006812:Humic Substances; D000097797:Glyphosate
keywords: Antimicrobial; Glyphosate; Humic acids; Microbiota