title: Patterns of cognitive performance in Subcortical Ischemic Vascular Disease (SIVD).
abstract: Subcortical ischemic vascular disease (SIVD) is characterized by extensive white-matter lesions and lacunar infarcts in deep gray matter. The aim of this study was to investigate patterns of cognitive impairment in patients with SIVD. In a retrospective analysis, the authors compared the cognitive performance of 58 patients meeting MRI-defined criteria for SIVD (26 women; 47.3%) with age- and gender-matched control subjects. SIVD patients showed impairments in measures of verbal fluency, verbal memory, speed of cognitive processing, and divided attention. There were no significant differences in constructional praxis, figurative memory, verbal recognition memory, or semantic processing.
authors.forename: Martin
authors.initials: M
authors.lastname: Scherr
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Krenn
authors.forename: Christian
authors.initials: C
authors.lastname: Sorg
authors.forename: Andrei
authors.initials: A
authors.lastname: Manoliu
authors.forename: Eugen
authors.initials: E
authors.lastname: Trinka
authors.forename: Hans
authors.initials: H
authors.lastname: Förstl
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Staffen
authors.forename: Hans Jürgen
authors.initials: HJ
authors.lastname: Bergmann
authors.forename: Margarita
authors.initials: M
authors.lastname: Kirschner
authors.forename: Mark
authors.initials: M
authors.lastname: McCoy
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002561:Cerebrovascular Disorders / Q000150:complications*; D003072:Cognition Disorders / Q000145:classification / Q000209:etiology*; D057286:Electronic Health Records / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012016:Reference Values; D012189:Retrospective Studies