title: Alkaloid production in Catharanthus roseus (L.) G. Don cell cultures. XIII. Effects of bioregulators on indole alkaloid biosynthesis.
abstract: A study on the effect of various bioregulators on the biosynthesis of ajmalicine (8) and catharanthine (9) in plant tissue cultures of Catharanthus roseus is described. It is shown that 1,1-dimethylpiperidine bromide (3) and 2-diethylaminoethyl-3,4-dimethylphenylether (7) are effective in increasing these alkaloid levels in the cell line PRL #200. Such studies may prove beneficial in larger scale experiments designed for the production of these alkaloids.
authors.affiliation: Department of Chemistry, University of British Columbia, 2036 Main Mall, V6T 1Y6, Vancouver, BC, Canada.
authors.forename: J P
authors.initials: JP
authors.lastname: Kutney
authors.forename: B
authors.initials: B
authors.lastname: Aweryn
authors.forename: K B
authors.initials: KB
authors.lastname: Chatson
authors.forename: L S
authors.initials: LS
authors.lastname: Choi
authors.forename: W G
authors.initials: WG
authors.lastname: Kurz