title: Enantiospecific synthesis fromD-fructose of (2S,5R)- and (2R,5R)-2-methyl-1,6-dioxaspiro[4.5]decane [the odor bouquet minor components ofParavespula vulgaris (L.)].
abstract: The synthesis of (2S,5R)-(1) and (2R,5R)-2-methyl-1,6-dioxaspiro [4.5]decane (2) from (2RS,5R,8R,9R,10S)-8,9,10-trihydroxy-2-methyl-1, 6-dioxaspiro[4.5]decane (8), obtained in five steps fromD-fructose using Wittig's methodology, reduction, and spiroketalation, has been accomplished by a Corey dideoxygenation at C-8,9, followed by a Barton deoxygenation at C-10, of the appropriately protected derivatives.
authors.affiliation: Department of Organic Chemistry, Faculty of Pharmacy, University of Granada, 18071, Granada, Spain.
authors.forename: I I
authors.initials: II
authors.lastname: Cubero
authors.forename: M T
authors.initials: MT
authors.lastname: Lopez-Espinosa
authors.forename: A C
authors.initials: AC
authors.lastname: Richardson