title: Tracheobronchopathia osteochondroplastica: a case report and literature review.
abstract: Tracheobronchopathia osteochondroplastica (TO) was diagnosed in a 52-year-old male with prolonged dry cough. Computerized tomography (CT) demonstrated that there were multiple calcified nodules in the anterolateral wall of trachea, sparing the posterior tracheal membrane. Fiberoptic bronchoscopy (FOB) showed that submucosal nodules protruded into the airway lumen. Histopathological exam found ossification and cartilage in the submucosa. TO is a scarce benign disorder, characterized by submucosal bony and cartilaginous nodules. The clinical manifestation is undistinguished and treatment is symptomatically dependent. FOB is a definitive diagnostic procedure. The characteristics of FOB finding are described as beaded, spiculate, rock garden, or cobble-stoned like nodules, which projected into the tracheobronchus lumen, sparing the posterior wall. Histopathological exam might re-confirm the diagnosis, finding ossification and cartilage in the submucosa of airway. Awareness of TO is significantly important, especially in chronic cough patients with special CT image, and FOB should be performed to confirm the diagnosis.
authors.affiliation: Department of respiratory medicine, Zhongshan hospital, Xiamen University, Xiamen 361004, China.
authors.forename: Xiao-Bin
authors.initials: XB
authors.lastname: Zhang
authors.forename: Hui-Qing
authors.initials: HQ
authors.lastname: Zeng
authors.forename: Xue-Ying
authors.initials: XY
authors.lastname: Cai
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Zhang
keywords: Tracheobronchopathia osteochondroplastica (TO); cough; fiberoptic bronchoscopy (FOB)