title: [PSA interest and prostatitis: literature review].
abstract: Prostatitis is easily diagnosed but sometimes associated with PSA measurement. An increased PSA in an asymptomatic patient may be associated with antibiotic use to eliminate the inflammatory part and to confirm prostate biopsy. It seems interesting to confirm or infirm these attitudes with a systematic review of the literature
  
  
  METHODS
  We performed a literature review using the words [prostatitis], [acute prostatitis], [prostate specific antigen], [PSA], in the MEDLINE, Pubmed and AMBASE database searching for articles in French or English published in the past 20 years.
  
  
  RESULTS
  PSA is not always increased during an acute prostatitis episode. An increased PSA in an asymptomatic man does not seem to be systematically correlated to prostate inflammation. Analyzing the studies, it seems inaccurate to measure PSA value during a febrile urinary infection episode in men. Systematic use of antibiotic to decrease PSA and not performing prostate biopsy is not relevant and may induce resistance to antibiotic and doesn't induce a reduction risk of having prostate biopsy.
  
  
  CONCLUSIONS
  PSA is unnecessary in case of febrile urinary tract infection in men.
authors.affiliation: Service d'urologie, CHRU Bretonneau, 2, boulevard Tonnellé, 37044 Tours, France; Université François-Rabelais PRES centre Val de Loire, 37044 Tours, France. Electronic address: f.bruyere@chu-tours.fr.
authors.forename: F
authors.initials: F
authors.lastname: Bruyère
authors.forename: M
authors.initials: M
authors.lastname: Amine Lakmichi
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D017430:Prostate-Specific Antigen / Q000097:blood* / Q000187:drug effects; D011472:Prostatitis / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D014552:Urinary Tract Infections / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D015415:Biomarkers; D017430:Prostate-Specific Antigen
keywords: PSA; Prostate; Prostatite; Prostatitis