title: Favre-Racouchot syndrome: a novel two-step treatment approach using the carbon dioxide laser.
abstract: BACKGROUND
  Favre-Racouchot syndrome (FRS) is both disfiguring and difficult to treat. Available medical and surgical therapies are of variable efficacy. Most treatments do not achieve complete resolution and do not show maintenance of therapeutic response.
  
  
  OBJECTIVE
  To assess the response to a novel two-step treatment using the CO2 laser in patients with FRS.
  
  
  METHODS
  Seven patients with FRS were treated with the CO2 laser in resurfacing mode with manual expression of comedones under infiltrative local anaesthesia. The procedure was completed in one treatment session lasting 30 min and the wound was left to heal by secondary intention. A topical antibiotic was applied to treated areas, which were covered with a nonadherent dressing. All patients were assessed 3 months postoperatively by the operating laser surgeon and a visual assessment of clinical response to treatment in comparison with pretreatment photographs was made. Patient satisfaction was also recorded.
  
  
  RESULTS
  All patients achieved complete resolution of FRS. The follow-up duration for our cohort ranged from 8 months to 3 years. Two patients required further treatment within a 2-3-year period from initial treatment. Disease relapse was noted over 1 year after the primary treatment; both these cases were smokers and repeat treatment with similar laser parameters maintained reproducible results. Our longest disease-free follow-up duration was 3 years postprimary treatment. The laser surgeons and patients reported high levels of therapeutic benefit and satisfaction with the results.
  
  
  CONCLUSIONS
  This two-step treatment of FRS (CO2 laser resurfacing and manual pressure-induced expression of comedones) is an effective and durable treatment for FRS with an excellent cosmetic outcome. Long-term follow-up beyond 3 years is planned to determine whether later recurrence occurs with this technique.
authors.affiliation: The Laser Division, Salford Royal Hospital, Stott Lane, Salford, Manchester, M6 8HD, U.K.
authors.forename: S
authors.initials: S
authors.lastname: Rai
authors.forename: V
authors.initials: V
authors.lastname: Madan
authors.forename: P J
authors.initials: PJ
authors.lastname: August
authors.forename: J E
authors.initials: JE
authors.lastname: Ferguson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005148:Facial Dermatoses / Q000601:surgery*; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation / Q000379:methods*; D054020:Lasers, Gas / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D017060:Patient Satisfaction; D012008:Recurrence; D016896:Treatment Outcome