title: Chemistry of primaquine I: acylation of the quinoline ring portion.
abstract: Investigation of derivatization of primaquine (1) with various perfluoroacylating reagents revealed that the quinoline ring portion of the drug undergoes unexpectedly facile acylation. Chemical and spectral evidence in support of the assigned structures is presented and discussed. Results of the evaluation of these new primaquine derivatives for antimalarial activity is reported.
authors.affiliation: , .
authors.forename: J D
authors.initials: JD
authors.lastname: McChesney
authors.forename: R C
authors.initials: RC
authors.lastname: Gupta