title: Thrombectomy in patients with large cerebral artery occlusion: a single-center experience with a new stent retriever.
abstract: BACKGROUND
  The Trevo device, a new stent retriever, may be utilized in patients with large cerebral artery occlusion.
  
  
  METHODS
  Fifty patients with large cerebral artery occlusion and treated with the Trevo device were analyzed. Patients may have received intravenous thrombolysis as a bridging concept in addition to thrombectomy. Outcome and recanalization parameters were documented using the National Institutes of Health Scale, the modified Ranking Scale (mRS) and Thrombolysis in Cerebral Infarction (TICI) score.
  
  
  RESULTS
  In all, 82% (95% confidence interval [CI]: 69%-91%) were documented with TICI 2b and 3. Good clinical outcome after 90 days (mRS ≤ 2) was assessed in 61% (95% CI: 46%-75%). Symptomatic intracerebral hemorrhage occurred in 6 patients (12%, 95% CI: 1%-17%). The overall mortality rate was 14% (95% CI: 6%-27%).
  
  
  CONCLUSIONS
  Thrombectomy with the new stent retriever device is feasible and effective and has an acceptable risk of intra-cerebral hemorrhage even in combination with pharmacological revascularization techniques.
authors.affiliation: 1Department of Neuroradiology, Paracelsus Medical University, Christian Doppler Clinic, Research Institute for Neurointervention, Salzburg, Austria.
authors.forename: Erasmia
authors.initials: E
authors.lastname: Broussalis
authors.forename: Eugen
authors.initials: E
authors.lastname: Trinka
authors.forename: Anna
authors.initials: A
authors.lastname: Wallner
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Hitzl
authors.forename: Monika
authors.initials: M
authors.lastname: Killer
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction; D002539:Cerebral Arterial Diseases / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D002543:Cerebral Hemorrhage / Q000209:etiology; D003131:Combined Modality Therapy; D003251:Constriction, Pathologic; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D012042:Registries; D012189:Retrospective Studies; D015607:Stents; D017131:Thrombectomy / Q000009:adverse effects / Q000295:instrumentation* / Q000401:mortality; D015912:Thrombolytic Therapy; D013997:Time Factors; D016896:Treatment Outcome
keywords: Trevo device; intravenous thrombolysis; large cerebral artery occlusion; stent retriever; stroke