title: Anthraquinones as phytoalexins in cell and tissue cultures of Cinchona spec.
abstract: The addition of autoclaved mycelia of Aspergillus niger and the known phytopathogenic fungus Phytophtora cinnamomi to cultured cells of Cinchona ledgeriana Moens. caused a marked increase in the anthraquinone content of the plant cells. This finding in combination with the antimicrobial activity of the anthraquinones isolated from calli of Cinchona pubescens Vahl. led to the conclusion that anthraquinones are phytoalexins.
authors.affiliation: Center for Bio-Pharmaceutical Sciences, Division of Pharmacognosy, State University of Leiden, Gorlaeus Laboratories, P.O. Box 9502, NL-2300 RA, Leiden, The Netherlands.
authors.forename: R
authors.initials: R
authors.lastname: Wijnsma
authors.forename: J T
authors.initials: JT
authors.lastname: Go
authors.forename: I N
authors.initials: IN
authors.lastname: van Weerden
authors.forename: P A
authors.initials: PA
authors.lastname: Harkes
authors.forename: R
authors.initials: R
authors.lastname: Verpoorte
authors.forename: A
authors.initials: A
authors.lastname: Baerheim Svendsen