title: Molecular diagnostics in the neoplasms of small intestine and appendix.
abstract: Adenocarcinoma of the small intestine is relatively rare in comparison to colorectal carcinoma. Adenocarcinoma of the small intestine arises through the adenoma-carcinoma sequence in the colon. However, adenocarcinomas arising in the background of inflammatory bowel disease develop through the dysplasia-carcinoma sequence. Most of the cases occur in the duodenum; however, adenocarcinoma occurring in association with Crohn disease is more common in the ileum.
authors.affiliation: Department of Pathology, PGY-3 Detroit Medical Center, Harper University Hospital, Wayne State University School of Medicine, 3990 John R Street, Detroit, MI 48201, USA.
authors.forename: Amarpreet
authors.initials: A
authors.lastname: Bhalla
authors.forename: Muhammad
authors.initials: M
authors.lastname: Zulfiqar
authors.forename: Michael
authors.initials: M
authors.lastname: Weindel
authors.forename: Vinod B
authors.initials: VB
authors.lastname: Shidham
mesh_terms: D006801:Humans; D007414:Intestinal Neoplasms / Q000175:diagnosis*; D007421:Intestine, Small / Q000473:pathology / Q000503:physiopathology; D025202:Molecular Diagnostic Techniques
keywords: Appendix; BRAF; KRAS; Microsatellite instability; Small intestine