title: Pertussis in the central-west region of Brazil: one decade study.
abstract: In many parts of the world, numerous outbreaks of pertussis have been described despite high vaccination coverage. In this article we report the epidemiological characteristics of pertussis in Brazil using a Surveillance Worksheet. Secondary data of pertussis case investigations reported from January 1999 to December 2008 recorded in the Information System for Notifiable Diseases (SINAN) and the Central Laboratory for Public Health (LACEN-MS) were utilized. The total of 561 suspected cases were reported and 238 (42.4%) of these were confirmed, mainly in children under six months (61.8%) and with incomplete immunization (56.3%). Two outbreaks were detected. Mortality rate ranged from 2.56% to 11.11%. The occurrence of outbreaks and the poor performance of cultures for confirming diagnosis are problems which need to be addressed. High vaccination coverage is certainly a good strategy to reduce the number of cases and to reduce the impact of the disease in children younger than six months.
authors.affiliation: Hospital Universitário, Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil. Electronic address: angelitadruzian@yahoo.com.br.
authors.forename: Angelita Fernandes
authors.initials: AF
authors.lastname: Druzian
authors.affiliation: Faculdade de Medicina, Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.
authors.forename: Yvone Maia
authors.initials: YM
authors.lastname: Brustoloni
authors.affiliation: Faculdade de Medicina, Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.
authors.forename: Sandra Maria do Valle Leone
authors.initials: SM
authors.lastname: Oliveira
authors.affiliation: Faculdade de Medicina, Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.
authors.forename: Vanessa Terezinha Gubert de
authors.initials: VT
authors.lastname: Matos
authors.affiliation: Hospital Universitário, Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.
authors.forename: Adriana Carla Garcia
authors.initials: AC
authors.lastname: Negri
authors.affiliation: State Department of Health, Campo Grande, MS, Brazil.
authors.forename: Clarice Souza
authors.initials: CS
authors.lastname: Pinto
authors.affiliation: State Department of Health, Campo Grande, MS, Brazil.
authors.forename: Silvia
authors.initials: S
authors.lastname: Asato
authors.affiliation: Hospital Universitário, Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.
authors.forename: Cirlene dos Santos Gonçalves
authors.initials: Cdos S
authors.lastname: Urias
authors.affiliation: Faculdade de Medicina, Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.
authors.forename: Anamaria Mello Miranda
authors.initials: AM
authors.lastname: Paniago
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D014611:Vaccination / Q000706:statistics & numerical data; D014917:Whooping Cough / Q000453:epidemiology* / Q000517:prevention & control
keywords: Bordetella pertussis; Epidemiology; Outbreak investigation; Pertussis; Whooping cough