title: Light scattering and light transmittance in a series of calcified single-piece hydrophilic acrylic intraocular lenses of the same design.
abstract: OBJECTIVE
  To evaluate light scattering and light transmittance of Ioflex hydrophilic acrylic intraocular lenses (IOLs) explanted because of clinically significant opacification secondary to calcification.
  
  
  METHODS
  John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
  
  
  METHODS
  Experimental study.
  
  
  METHODS
  Seven explanted and 8 control Ioflex IOLs were studied. Gross and light microscopy of all the IOLs were performed. Light scattering was measured with a Scheimpflug camera, and light transmittance was assessed with a spectrophotometer. Analyses were performed at room temperature in the hydrated state, and findings of the explanted and control IOLs were compared.
  
  
  RESULTS
  Light scattering was 219.71 computer compatible tape (CCT) ± 2.62 (SD) for explanted IOLs and 4.75 ± 2.50 CCT for controls. The mean light transmittance in the visible light spectrum was 75.94% to 87.25% for explanted IOLs and 97.54% to 98.97% for controls. The most striking finding was variable degrees of light transmittance between 290 nm and 350 nm (ultraviolet-A and B radiation) in the explanted and control IOLs with expiration dates in 2009/2010 but 0% transmittance in this region in all controls with expiration dates in 2011/2012.
  
  
  CONCLUSIONS
  Light scattering was extremely high and transmittance was significantly reduced in calcified IOLs. Differences in transmittance observed in the 290 to 350 nm region between IOLs with different expiration dates were related to use of different hydrophilic acrylic raw material suppliers in the manufacture of the IOLs, highlighting the complexity of IOL calcification investigations.
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Barra, Werner, Morris), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; Visão Institutos Oftalmológicos Associados (Barra, Costa, Ribeiro), Brasília, Altino Ventura Foundation (Ventura), Recife, and Visum Oftalmologia (Dornelles), Porto Alegre, Brazil.
authors.forename: Daniel
authors.initials: D
authors.lastname: Barra
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Barra, Werner, Morris), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; Visão Institutos Oftalmológicos Associados (Barra, Costa, Ribeiro), Brasília, Altino Ventura Foundation (Ventura), Recife, and Visum Oftalmologia (Dornelles), Porto Alegre, Brazil. Electronic address: liliana.werner@hsc.utah.edu.
authors.forename: Liliana
authors.initials: L
authors.lastname: Werner
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Barra, Werner, Morris), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; Visão Institutos Oftalmológicos Associados (Barra, Costa, Ribeiro), Brasília, Altino Ventura Foundation (Ventura), Recife, and Visum Oftalmologia (Dornelles), Porto Alegre, Brazil.
authors.forename: João Luiz Pacini
authors.initials: JL
authors.lastname: Costa
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Barra, Werner, Morris), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; Visão Institutos Oftalmológicos Associados (Barra, Costa, Ribeiro), Brasília, Altino Ventura Foundation (Ventura), Recife, and Visum Oftalmologia (Dornelles), Porto Alegre, Brazil.
authors.forename: Caleb
authors.initials: C
authors.lastname: Morris
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Barra, Werner, Morris), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; Visão Institutos Oftalmológicos Associados (Barra, Costa, Ribeiro), Brasília, Altino Ventura Foundation (Ventura), Recife, and Visum Oftalmologia (Dornelles), Porto Alegre, Brazil.
authors.forename: Tiago
authors.initials: T
authors.lastname: Ribeiro
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Barra, Werner, Morris), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; Visão Institutos Oftalmológicos Associados (Barra, Costa, Ribeiro), Brasília, Altino Ventura Foundation (Ventura), Recife, and Visum Oftalmologia (Dornelles), Porto Alegre, Brazil.
authors.forename: Bruna Vieira
authors.initials: BV
authors.lastname: Ventura
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Barra, Werner, Morris), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; Visão Institutos Oftalmológicos Associados (Barra, Costa, Ribeiro), Brasília, Altino Ventura Foundation (Ventura), Recife, and Visum Oftalmologia (Dornelles), Porto Alegre, Brazil.
authors.forename: Fábio
authors.initials: F
authors.lastname: Dornelles
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D000369:Aged, 80 and over; D001672:Biocompatible Materials; D002114:Calcinosis / Q000209:etiology*; D020878:Device Removal; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007910:Lenses, Intraocular; D008027:Light; D008875:Middle Aged; D055095:Optics and Photonics; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012542:Scattering, Radiation; D041623:Tomography, Optical Coherence
chemical_list: D000180:Acrylic Resins; D001672:Biocompatible Materials