title: Latent class analysis of obsessive-compulsive symptoms in a clinical sample.
abstract: OBJECTIVE
  Obsessive-compulsive disorder (OCD) is probably a heterogeneous condition. To date, research investigating the symptom structure of OCD has generally focused on variable-classification approaches, primarily factor analysis. Our aim was to use the latent class analysis, an advanced individual-classification method, in order to define homogeneous sub-groups based on the Yale-Brown Obsessive-Compulsive Scale Check List (Y-BOCS CL) assessments within 193 outpatients with OCD.
  
  
  METHODS
  Latent class analysis of 13 obsessive-compulsive symptom-clusters measured by the Yale-Brown Obsessive-Compulsive Scale Check List was performed. Associations of demographic and clinical features with latent class membership were tested by using logistic regression models. Differences in severity of obsessive-compulsive symptoms, obsessive beliefs, and depressive symptomotology between latent classes were evaluated with the chi-square likelihood test.
  
  
  RESULTS
  Latent class analysis models of best fit yielded 3 latent classes: "autogenous obsessions", "reactive obsessive-compulsive", and "reactive obsessions". Outpatients in reactive obsessive-compulsive group reported significantly higher scores on the Y-BOCS global, obsessions, and compulsions scales than outpatients in other two sub-groups. Participants in reactive obsessive-compulsive group were predominantly female, single, and had a history of family psychopathology; whereas autogenous and reactive obsessions groups were predominantly male. There were no differences in severity of depression and obsessive belief domains.
  
  
  CONCLUSIONS
  The results provide support for the validity of autogenous/reactive distinction for OCD. These three classes may have important implications for research and clinical purposes.
authors.affiliation: Department of Psychiatry, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey. Electronic address: abdullahatli@yandex.com.tr.
authors.forename: Abdullah
authors.initials: A
authors.lastname: Atli
authors.affiliation: Department of Psychology, Faculty of Arts, Yuzuncu Yil University, Van 65200, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Boysan
authors.affiliation: Department of Psychiatry, Gebze Fatih State Hospital, Kocaeli 41400, Turkey.
authors.forename: Nuralay
authors.initials: N
authors.lastname: Çetinkaya
authors.affiliation: Department of Psychiatry, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
authors.forename: Mahmut
authors.initials: M
authors.lastname: Bulut
authors.affiliation: Department of Psychiatry, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
authors.forename: Yasin
authors.initials: Y
authors.lastname: Bez
mesh_terms: D000293:Adolescent; D000328:Adult; D003192:Compulsive Behavior / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009770:Obsessive Behavior / Q000175:diagnosis* / Q000523:psychology; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis* / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D055815:Young Adult