title: Iron is maintained as Fe(II) under aerobic conditions in erythroid cells.
abstract: It was found that in rabbit erythrocytes loaded with Fe(II) (using the ionophore, A23187) over 90% of this metal is maintained in its ferrous form. In rabbit reticulocytes more than 50% of the transferrin-donated nonheme iron proved to be divalent. These results strongly suggest that under aerobic conditions the intracellular environment of intact erythroid cells is reducing for iron.
authors.affiliation: National Institute of Haematology and Blood Transfusion, 1113, Budapest, Hungary.
authors.forename: A
authors.initials: A
authors.lastname: Egyed'
authors.forename: P
authors.initials: P
authors.lastname: Saltman