title: Malignant inflammatory myofibroblastic tumor of the maxillary sinus.
abstract: Inflammatory myofibroblastic tumors (IMTs) are extremely rare neoplasms with a variable natural history and biologic behavior, ranging from completely benign to malignant tumors with fatal outcome. They have no common identifiable cause, although some authors have assumed that any inflammatory stimulus may cause these pseudotumors. They are most commonly found in the lungs. Extrapulmonary sites include abdomen, retroperitoneum and extremities. IMTs rarely affect the head and neck, but the most common subsites in this region include the orbit, larynx, mouth, tonsils, parapharyngeal space, thyroid, parotid and lacrimal glands. There are few reports of inflammatory pseudotumors in the paranasal sinuses. In the maxillary sinus, the initial presenting sign is usually a nonspecific sinonasal mass, which has been growing over a period of weeks or months. On rare occasions, IMT may exhibit malignant transformation. Herein we present a rare case of pathologically proved IMT with malignant transformation which originated in the maxillary sinus of a 29-year-old male.
authors.affiliation: Department of Oral and Maxillofacial Pathology, Faculty of Dentistry and Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Jahanshah
authors.initials: J
authors.lastname: Salehinejad
authors.forename: Mahdi
authors.initials: M
authors.lastname: Pazouki
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Gerayeli
keywords: Inflammatory myofibroblastic tumor; malignant transformation; maxillary sinus