title: A safe and efficient flow oxidation of aldehydes with O2.
abstract: A safe, straightforward, and atom economic approach for the oxidation of aliphatic aldehydes to the corresponding carboxylic acids within a continuous flow reactor is reported. Typically, the reaction is performed at room temperature using 5 bar of oxygen in PFA tubing and does require neither additional catalysts nor radical initiators except for those already contained in the starting materials. In some cases, a catalytic amount of a Mn(II) catalyst is added. Such a flow process may prove to be a valuable alternative to traditionally catalyzed aerobic processes.
authors.affiliation: Laboratoire de Génie des Procédés Catalytiques (LGPC), UMR 5285 CNRS/CPE Lyon, Université de Lyon , 43 boulevard du 11 novembre 1918, 69616 Villeurbanne cedex, France, and Conservatoire National des Arts et Métiers, Ecole SITI , Département CASER, Equipe CGP, 2 rue Conté, 75003 Paris, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Vanoye
authors.forename: Asma
authors.initials: A
authors.lastname: Aloui
authors.forename: Mertxe
authors.initials: M
authors.lastname: Pablos
authors.forename: Régis
authors.initials: R
authors.lastname: Philippe
authors.forename: Aurélien
authors.initials: A
authors.lastname: Percheron
authors.forename: Alain
authors.initials: A
authors.lastname: Favre-Réguillon
authors.forename: Claude
authors.initials: C
authors.lastname: de Bellefon