title: A case of in-stent neoatherosclerosis 10 years after carotid artery stent implantation: observation with optical coherence tomography and plaque histological findings.
abstract: We report a patient's case of slow progressive in-stent restenosis 10 years after bare-metal stent implantation to his carotid artery. We treated the patient with an additional stent placement under a distal filter protection device. Optical coherence tomographic assessment and plaque histology during the carotid artery stenting (CAS) revealed atheromatous change at in-stent neointima, which contained lipid-rich plaque and calcification deposits. These findings suggest that in-stent neoatherosclerosis may play an important role in the pathogenesis of very late stent restenosis after CAS.
authors.affiliation: Department of Neurological Surgery, Wakayama Medical University.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Matsumoto
authors.forename: Rie
authors.initials: R
authors.lastname: Yako
authors.forename: Osamu
authors.initials: O
authors.lastname: Masuo
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Hirayama
authors.forename: Yuji
authors.initials: Y
authors.lastname: Uematsu
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Nakao
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000628:therapy; D002545:Brain Ischemia / Q000209:etiology; D002114:Calcinosis / Q000209:etiology / Q000473:pathology; D002340:Carotid Artery Diseases / Q000209:etiology* / Q000473:pathology; D002343:Carotid Artery, Internal / Q000473:pathology*; D016893:Carotid Stenosis / Q000628:therapy; D023903:Coronary Restenosis / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D058426:Neointima / Q000473:pathology*; D058226:Plaque, Atherosclerotic / Q000737:chemistry / Q000473:pathology*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D015607:Stents; D041623:Tomography, Optical Coherence
chemical_list: D010975:Platelet Aggregation Inhibitors