title: A rare presentation of Henoch-Schönlein purpura and myocardial infarction at the 5th decade of life.
abstract: Henoch-Schönlein purpura is an IgA-mediated, autoimmune, hypersensitivity vasculitis of childhood that results in a triad of symptoms, including a purpuric rash occurring on the lower extremities, abdominal pain or renal involvement, and arthritis. However, any of the triad may be absent, which often leads to a confusion in diagnosing the condition. Although the cause is unknown, Henoch-Schönlein purpura (HSP) is often associated with infectious agents, such as group A streptococci and mycoplasma. It has also been associated with food reactions, exposure to cold, insect bites, and drug allergies. The treatment is supportive and needs close followup of renal status. This report describes a rare presentation of Henoch-Schönlein purpura with coronary vasculitis which leads to myocardial infarction at the age of 53. Henoch-Schönlein purpura was diagnosed on the basis of no infection, accelerated ESR (35 mm/h), normal platelet count, positive skin biopsy, proteinuria, and negative searches for rheumatoid factor (RF), antinuclear antibody (ANA), antineutrophil cytoplasmic antibodies (ANCA), and anti-dsDNA.
authors.affiliation: Department of Cardiology, Kerala Institute of Medical Sciences (KIMS).
authors.forename: Rajesh
authors.initials: R
authors.lastname: Rajan
authors.forename: Peter K
authors.initials: PK
authors.lastname: Joseph
authors.forename: Vijayaraghavan
authors.initials: V
authors.lastname: Govindan
keywords: Henoch–Schönlein purpura; coronary vasculitis; myocardial infarction