title: Ischemic stroke hospital admission associated with ambient temperature in Jinan, China.
abstract: BACKGROUND
  This study estimated the effects of ambient temperature and relative humidity on hospital admissions for ischemic stroke during 1990-2009 in Jinan, China.
  
  
  METHODS
  To account for possible delayed effects and harvesting effect, we examined the impact of meteorological factors up to 30 days before each admission using a distributed lag non-linear model; we controlled for season, long-term trend, day of week and public holidays in the analysis. Stratified analyses were also done for summer and winter.
  
  
  RESULTS
  A total of 1,908 ischemic stroke hospital admissions were observed between 1990 and 2009. We found a strong non-linear acute effect of daily temperatures on ischemic stroke hospital admission. With the mean temperature 15°C as the reference, the relative risk (RR) was 1.43 (95% confidence interval (CI): 1.10-1.85) for 0°C daily temperature on the same day, and 0.43 (95% CI: 0.31-0.59) for 30°C daily temperature on the same day, respectively. The effect of ambient temperature was similar in summer and winter. No significant association was observed between relative humidity and ischemic stroke hospitalization.
  
  
  CONCLUSIONS
  Low temperature might be a risk factor for ischemic stroke, and high temperature might be protective factor of ischemic stroke occurrence in Jinan, China.
authors.affiliation: Department of Neurology, Qilu Hospital of Shandong University, Jinan, China.
authors.forename: Qinzhou
authors.initials: Q
authors.lastname: Wang
authors.forename: Cuilian
authors.initials: C
authors.lastname: Gao
authors.forename: Hongchun
authors.initials: H
authors.lastname: Wang
authors.forename: Lingling
authors.initials: L
authors.lastname: Lang
authors.forename: Tao
authors.initials: T
authors.lastname: Yue
authors.forename: Hualiang
authors.initials: H
authors.lastname: Lin
mesh_terms: D002681:China / Q000453:epidemiology; D006760:Hospitalization; D006801:Humans; D006813:Humidity; D017711:Nonlinear Dynamics; D010343:Patient Admission; D012307:Risk Factors; D012621:Seasons; D020521:Stroke / Q000453:epidemiology*; D013696:Temperature; D013997:Time Factors