title: Ortho vs ipso: site-selective Pd and norbornene-catalyzed arene C-H amination using aryl halides.
abstract: A Pd and norbornene-catalyzed ortho-arene amination via Catellani-type C-H functionalization is reported. Aryl halides are used as substrates; N-benzoyloxyamines and isopropanol are employed as the amine source (oxidant) and reductant respectively. Examples are provided in 50-99% yields with high functional group tolerance. This method gives complementary site selectivity at the ortho- instead of ipso-position of aryl halides.
authors.affiliation: Department of Chemistry, University of Texas at Austin , Austin, Texas 78712, United States.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Dong
authors.forename: Guangbin
authors.initials: G
authors.lastname: Dong
mesh_terms: D000586:Amination; D001896:Boron Compounds / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D006219:Halogens / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D001896:Boron Compounds; D006219:Halogens; D010165:Palladium; D002244:Carbon; D006859:Hydrogen