title: Neuromodulation for eating disorders: obesity and anorexia.
abstract: Extremes of eating disorders (ED) have become prevalent in both developed and developing countries. Available therapies, though largely effective, fail in a substantial number of patients and carry considerable side effects. Morbid obesity and anorexia nervosa (AN) represent important causes of morbidity and mortality among young adults. Morbid obesity affects disproportionate numbers of children. AN is also important for its high mortality in young adults. The challenges of effectively treating AN are well recognized. In this article, important aspects of ED are reviewed in detail and novel approaches to the treatment of ED are proposed.
authors.affiliation: Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; HCor Neuroscience, Hospital do Coração, Rua Abilio Soares, 250, Paraiso, São Paulo 05005-000, Brazil.
authors.forename: Alessandra A
authors.initials: AA
authors.lastname: Gorgulho
authors.forename: Julio L B
authors.initials: JL
authors.lastname: Pereira
authors.forename: Scott
authors.initials: S
authors.lastname: Krahl
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Lemaire
authors.forename: Antonio
authors.initials: A
authors.lastname: De Salles
mesh_terms: D000855:Anorexia / Q000628:therapy*; D046690:Deep Brain Stimulation; D006801:Humans; D007031:Hypothalamus / Q000502:physiology; D009765:Obesity / Q000628:therapy*
keywords: Deep brain stimulation; Eating disorders; Hypothalamus; Neuromodulation