title: Lack of MERS coronavirus neutralizing antibodies in humans, eastern province, Saudi Arabia.
abstract: We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.
authors.forename: Stefanie
authors.initials: S
authors.lastname: Gierer
authors.forename: Heike
authors.initials: H
authors.lastname: Hofmann-Winkler
authors.forename: Waleed H
authors.initials: WH
authors.lastname: Albuali
authors.forename: Stephanie
authors.initials: S
authors.lastname: Bertram
authors.forename: Abdullah M
authors.initials: AM
authors.lastname: Al-Rubaish
authors.forename: Abdullah A
authors.initials: AA
authors.lastname: Yousef
authors.forename: Awatif N
authors.initials: AN
authors.lastname: Al-Nafaie
authors.forename: Amein K
authors.initials: AK
authors.lastname: Al-Ali
authors.forename: Obeid E
authors.initials: OE
authors.lastname: Obeid
authors.forename: Khaled R
authors.initials: KR
authors.lastname: Alkharsah
authors.forename: Stefan
authors.initials: S
authors.lastname: Pöhlmann
mesh_terms: D000328:Adult; D057134:Antibodies, Neutralizing / Q000097:blood / Q000276:immunology*; D000914:Antibodies, Viral / Q000097:blood / Q000276:immunology*; D017934:Coronavirus / Q000276:immunology*; D018352:Coronavirus Infections / Q000453:epidemiology* / Q000276:immunology* / Q000635:transmission; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012529:Saudi Arabia / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D057134:Antibodies, Neutralizing; D000914:Antibodies, Viral
keywords: MERS coronavirus; MERS-CoV; Middle East respiratory syndrome coronavirus; Saudi Arabia; coronavirus; neutralizing antibodies; plasma; pseudotyping; respiratory infections; seroprevalence; serum; spike; viruses