title: [Combinations of bronchodilators in COPD therapy--"fashionable" or rule?].
abstract: Combinations of bronchodilators are becoming more and more common in COPD guidelines but also in the practitioner's hand. It starts from the complementary action of two classes of bronchodilators, inhaled anticholinergics and beta 2 adrenergics and have a dynamic evolution analysed in this article, starting with the new rules introduced by the GOLD guide until the possible changes in attitudes of the therapist in the moment when they will have them at their fingertips.
authors.affiliation: Institutul de Pneumologie Marius Nasto, Bucureşti. mihaltan@starnets.ro
authors.forename: Florin
authors.initials: F
authors.lastname: Mihălţan
mesh_terms: D000280:Administration, Inhalation; D058672:Adrenergic beta-2 Receptor Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D018680:Cholinergic Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D017410:Practice Guidelines as Topic; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy* / Q000503:physiopathology; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D058672:Adrenergic beta-2 Receptor Antagonists; D001993:Bronchodilator Agents; D018680:Cholinergic Antagonists