title: Gastrointestinal drug interactions affecting the elderly.
abstract: With the burgeoning elderly population in the United States, drug interactions are an increasing concern because of altered drug metabolism associated with age and polypharmacy. This article describes interactions between drugs used in common gastrointestinal diseases, including acid peptic disease, diarrhea, constipation, endoscopic procedural sedation, and inflammatory bowel disease, and those used to treat 5 common geriatric primary care diseases: hypertension, diabetes, hyperlipidemia, arthritis, and psychiatric illnesses.
authors.affiliation: Division of Gastroenterology, Albany Medical Center, Albany, NY, USA.
authors.forename: Mandeep
authors.initials: M
authors.lastname: Singh
authors.forename: Shawn
authors.initials: S
authors.lastname: Chaudhary
authors.forename: Sadra
authors.initials: S
authors.lastname: Azizi
authors.forename: Jesse
authors.initials: J
authors.lastname: Green
mesh_terms: D000368:Aged; D002908:Chronic Disease / Q000145:classification / Q000188:drug therapy / Q000453:epidemiology; D015897:Comorbidity; D004347:Drug Interactions; D005765:Gastrointestinal Agents / Q000494:pharmacology*; D005767:Gastrointestinal Diseases / Q000145:classification / Q000188:drug therapy / Q000453:epidemiology; D006301:Health Services Needs and Demand; D006801:Humans; D054539:Medication Therapy Management; D019338:Polypharmacy; D015995:Prevalence; D011320:Primary Health Care / Q000379:methods / Q000592:standards; D020379:Risk Adjustment
chemical_list: D005765:Gastrointestinal Agents
keywords: Acid peptic disease; Common gastrointestinal conditions; Constipation; Diarrhea; Drug interactions; Endoscopic procedural sedation; Geriatrics; Inflammatory bowel disease