title: [Endogenous endophthalmitis: case report and brief review of a serious ocular disease].
abstract: BACKGROUND
  Endogenous endophthalmitis (EE) is a prevalent but serious disease. Our aim was to describe cases of EE, with emphasis in the risk factors and the improvement of the prognosis.
  
  
  METHODS
  A review of EE cases was done between 1996-2011 in a secondary care hospital in Spain. The reported variables were: comorbidities, isolated microorganisms, susceptibility to antimicrobial treatment and visual prognosis.
  
  
  RESULTS
  9 cases of EE were analyzed. All had some underlying disease, diabetes mellitus being the most frequent. Seven of the nine cases had a history of eye injury. Extraocular source of infection was identified in 7 cases, with predominantly gastrointestinal disease. Most microorganisms were isolated from blood cultures. The visual prognosis was unfavorable in five patients and was associated with virulent microorganisms and delayed treatment.
  
  
  CONCLUSIONS
  EE is a rare disease that involve immunocompromised patients with ophthalmic disease. To improve prognosis, appropriate diagnosis and early treatment is require. Therefore, we recommend funduscopy examination in patients with sepsis, risk factors and prior history of ocular disease.
authors.affiliation: Laboratorio de Microbiología, Hospital General La Mancha, Alcázar de San Juan, España.
authors.forename: María A
authors.initials: MA
authors.lastname: Asencio-Egea
authors.forename: María
authors.initials: M
authors.lastname: Huertas-Vaquero
authors.forename: Rafael
authors.initials: R
authors.lastname: Carranza-González
authors.forename: Javier
authors.initials: J
authors.lastname: Cells-Sánchez
authors.forename: Fernando
authors.initials: F
authors.lastname: González-del Valle
authors.forename: José M
authors.initials: JM
authors.lastname: Tenías-Burillo
authors.forename: José R
authors.initials: JR
authors.lastname: Barberá-Farré
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D009877:Endophthalmitis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D055815:Young Adult