title: Primary spinal neurocytoma involving the medulla oblongata: two case reports and a literature review.
abstract: Central neurocytoma is a rare neuroectodermal tumor found in young adults. These tumors are generally located in the lateral or third ventricles. Extraventricular neurocytoma in the spinal cord is extremely rare. We report on two patients with primary spinal neurocytomas who presented with progressive numbness and weakness in the limbs. Both patients had intramedullary masses between the medulla and the upper thoracic levels. The clinical, radiological, surgical, and pathological features of this abnormality are discussed, and all 20 reported cases were reviewed. In conclusion, neurocytoma should be included in the differential diagnosis of a spinal intramedullary tumor, and subtotal resection is acceptable for a relatively favorable prognosis if gross total removal is unachievable. The efficacy of adjuvant radiochemotherapy to control tumor recurrence is unknown.
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University.
authors.forename: Liang
authors.initials: L
authors.lastname: Wu
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Deng
authors.forename: Chenlong
authors.initials: C
authors.lastname: Yang
authors.forename: Lei
authors.initials: L
authors.lastname: Zhao
authors.forename: Tao
authors.initials: T
authors.lastname: Yang
authors.forename: Yulun
authors.initials: Y
authors.lastname: Xu
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002574:Cervical Vertebrae; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007796:Laminectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D008526:Medulla Oblongata; D008875:Middle Aged; D018365:Neoplasm, Residual; D018306:Neurocytoma / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D013115:Spinal Canal / Q000473:pathology; D013117:Spinal Cord Compression / Q000209:etiology; D013125:Spinal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000601:surgery; D013904:Thoracic Vertebrae
chemical_list: D014408:Biomarkers, Tumor