title: Sinus node dysfunction in adult systemic lupus erythematosus flare: A case report.
abstract: Cardiac involvement can affect up to 50% of the systemic lupus erythematosus (SLE) patients but conduction system disturbances in SLE are less commonly described. For an early detection of this complication in the acute phase of SLE a whole cardiovascular examination and periodic electrocardiographic monitoring are recommended. We describe a patient who was diagnosed with flare up of lupus activity manifesting as sinus node dysfunction presenting as profound sinus bradycardia. She was successfully treated with high-dose methylprednisolone therapy.
authors.affiliation: Department of Rheumatology, Kocaeli University, Faculty of Medicine , Kocaeli , Turkey.
authors.forename: Baris
authors.initials: B
authors.lastname: Yilmazer
authors.forename: Mursel
authors.initials: M
authors.lastname: Sali
authors.forename: Fulya
authors.initials: F
authors.lastname: Cosan
authors.forename: Ayse
authors.initials: A
authors.lastname: Cefle
mesh_terms: D001919:Bradycardia / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D008775:Methylprednisolone / Q000627:therapeutic use; D012804:Sick Sinus Syndrome / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone
keywords: Methylprednisolone; Sinus bradycardia; Systemic lupus erythematosus