title: Nonalcoholic fatty liver disease epidemic and its implications for liver transplantation.
abstract: Nonalcoholic steatohepatitis (NASH) is increasingly recognized as the most common chronic liver disease worldwide. The aim of this study is to investigate the transplantation trends of liver transplant (LT) recipients with NASH. Using the United Network for Organ Sharing database, we found a steady increase in LT rate especially in those more than 65 years old. We identified differences across ethnic groups and United Network for Organ Sharing regions. This study highlights the impact of the rising prevalence of NASH on the demand for LT and provides invaluable information to healthcare policymakers and the transplant community about the target groups and geographic location for focused and early intervention.
authors.affiliation: 1 Tampa General Medical Group, Tampa, FL. 2 Address correspondence to: Nyingi Kemmer, M.D., M.P.H., M.Sc., Tampa General Medical Group, 409 Bayshore Boulevard, Tampa, FL 33606.
authors.forename: Nyingi
authors.initials: N
authors.lastname: Kemmer
authors.forename: Guy W
authors.initials: GW
authors.lastname: Neff
authors.forename: Edson
authors.initials: E
authors.lastname: Franco
authors.forename: Hussein
authors.initials: H
authors.lastname: Osman-Mohammed
authors.forename: John
authors.initials: J
authors.lastname: Leone
authors.forename: Erin
authors.initials: E
authors.lastname: Parkinson
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Cece
authors.forename: Angel
authors.initials: A
authors.lastname: Alsina
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D005006:Ethnicity; D005234:Fatty Liver / Q000175:diagnosis / Q000208:ethnology / Q000601:surgery*; D005260:Female; D006085:Graft Survival; D006801:Humans; D015994:Incidence; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D065626:Non-alcoholic Fatty Liver Disease; D012189:Retrospective Studies; D017678:Sex Distribution; D014481:United States / Q000453:epidemiology