title: Comparison of a fractional bipolar radiofrequency device and a fractional erbium-doped glass 1,550-nm device for the treatment of atrophic acne scars: a randomized split-face clinical study.
abstract: BACKGROUND
  A fractional erbium-doped glass 1,550-nm and a fractional bipolar radiofrequency (RF) device are effective in the treatment of atrophic acne scars.
  
  
  OBJECTIVE
  To compare the clinical effectiveness and side effects of fractional bipolar RF with those of fractional erbium-doped glass in atrophic acne scars treatment.
  
  
  METHODS
  Twenty Thai subjects with atrophic acne scars received three split-face monthly treatments, one side with fractional bipolar RF and the other with fractional erbium-doped glass. Three independent physicians and patients evaluated improvement in acne scars 4 weeks after the last treatment. Side effects were also recorded after each treatment.
  
  
  RESULTS
  The study found significant improvement in acne scars after treatment with fractional bipolar RF and with a fractional erbium-doped glass device without a statistically significant difference between the two devices. The side effects of both devices were pain, transient facial erythema, and scab formation. The pain score with fractional erbium-doped glass was higher than that with fractional bipolar RF, but duration of scab shedding was shorter. One case had postinflammatory hyperpigmentation on only the side treated with fractional erbium-doped glass.
  
  
  CONCLUSIONS
  Fractional bipolar RF and fractional erbium-doped glass have similar effectiveness for the treatment of atrophic acne scars.
authors.affiliation: Department of Dermatology, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand.
authors.forename: Nopnarueporn
authors.initials: N
authors.lastname: Rongsaard
authors.forename: Paisal
authors.initials: P
authors.lastname: Rummaneethorn
mesh_terms: D000152:Acne Vulgaris / Q000150:complications / Q000532:radiotherapy*; D000328:Adult; D001284:Atrophy; D002921:Cicatrix / Q000209:etiology / Q000473:pathology / Q000532:radiotherapy*; D019583:Dose Fractionation, Radiation; D004871:Erbium; D005260:Female; D006801:Humans; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D004871:Erbium