title: Evolutive study of relapsing-remitting multiple sclerosis with cervical proton magnetic resonance spectroscopy. A case report.
abstract: We used quantitative proton magnetic resonance spectroscopy ((1)H-MRS) to evaluate mean relative concentrations ratios for NAA, Cr, Cho and mI during the study of cervical spinal cord plaques in a relapsing-remitting multiple sclerosis (RRMS). A cervical spine MR exam was repeated five times on the following days for two months starting from the onset of a relapse phase, using a 3T whole-body system, with the voxel placed along the demyelinazation lesion. The quantification results were compared with the healthy metabolites content. Quantitative cervical spectroscopy is a reliable tool and can offer important metabolic information as already used on the brain to evaluate the severity, progression and pathogenesis of multiple sclerosis.
authors.affiliation: Neurosciences Department, Neuroradiology Unit, Bellaria Hospital; Bologna, Italy - l.albiniriccioli@ausl.bo.it.
authors.forename: L
authors.initials: L
authors.lastname: Albini Riccioli
authors.forename: A F
authors.initials: AF
authors.lastname: Marliani
authors.forename: V
authors.initials: V
authors.lastname: Clementi
authors.forename: I
authors.initials: I
authors.lastname: Bartolomei
authors.forename: R
authors.initials: R
authors.lastname: Agati
authors.forename: M
authors.initials: M
authors.lastname: Leonardi