title: Mean platelet volume in ocular Behçet's disease.
abstract: OBJECTIVE
  To determine whether mean platelet volume (MPV) is an indicator of disease severity in ocular Behçet's Disease (BD).
  
  
  METHODS
  The study population was 30 newly diagnosed ocular BD patients who presented with active uveitis. These patients had no past history of smoking, drug use, or systemic diseases including diabetes mellitus, hypertension, cardiovascular disease, and renal disease. A control group consisting of 34 healthy individuals was included for comparison. MPV measurements were performed serially upon presentation with active uveitis and at one and three month thereafter in BD group whereas only at presentation in the controls.
  
  
  RESULTS
  Upon presentation with active uveitis, the mean MPV levels were 7.88 ± 1.14 femtoliters (fL) for BD group. During the posttreatment follow-up period at first and third months, BD patients demonstrated a mean MPV level of 7.71 ± 1.12 fL and 7.65 ± 1.04 fL, respectively. The mean MPV value of control group, was 8.39 ± 0.66 fL at presentation. Fluctuations in MPV values were not significant in the BD group, while there was a significant difference between the initial measurements of the BD and control groups.
  
  
  CONCLUSIONS
  MPV measurement in ocular BD is not a predictive laboratory test to determine the clinical improvement in early stages following classical immunosuppressive treatment.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.
authors.forename: Fatih Mehmet
authors.initials: FM
authors.lastname: Türkcü
authors.forename: Abdullah Kürşat
authors.initials: AK
authors.lastname: Cingü
authors.forename: Harun
authors.initials: H
authors.lastname: Yüksel
authors.forename: Yasin
authors.initials: Y
authors.lastname: Cınar
authors.forename: Meltem
authors.initials: M
authors.lastname: Akkurt
authors.forename: Muhammed
authors.initials: M
authors.lastname: Sahin
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Ozkurt
authors.forename: Alparslan
authors.initials: A
authors.lastname: Sahin
authors.forename: Ihsan
authors.initials: I
authors.lastname: Caça
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D011237:Predictive Value of Tests; D014605:Uveitis / Q000097:blood* / Q000175:diagnosis / Q000209:etiology