title: DMEK Complications.
abstract: OBJECTIVE
  The aim of this study was to describe the incidence and management of the complications of Descemet membrane endothelial keratoplasty (DMEK) surgery performed by a single surgeon.
  
  
  METHODS
  This is a retrospective case series. The clinical records of 72 consecutive patients (75 eyes) who underwent a DMEK with a minimum of 1-month postoperative follow-up were reviewed for adverse outcomes. The surgeon's first 50 operated eyes over a 4-month period were excluded from this study.
  
  
  RESULTS
  All the eyes included were pseudophakic with endothelial failure resulting from either Fuchs dystrophy, pseudophakic bullous keratopathy, or a failed Descemet stripping automated endothelial keratoplasty. All the eyes had a total resolution of corneal edema. Donor tissue peeling was unsuccessful in 2 of 75 cases. Primary failure occurred in 2 of 75 cases; a repeated DMEK provided successful visual rehabilitation in both cases. Rebubbling was performed in 2 of 75 eyes, which was unsuccessful in both cases. Peripheral donor scrolls/contractions occurred in 17 of 75 eyes, and all were asymptomatic with 14 of 17 eyes (82%) located in the inferior quadrants. There were no cases of pupillary block glaucoma, inverted donors, or free-floating donors. Preliminary best spectacle-corrected visual acuity was 20/25 at postoperative month 3 with corresponding excellent endothelial counts (mean of 2112 cells per square millimeter in 22 patients with 6 months of follow-up).
  
  
  CONCLUSIONS
  The safety and rate of operative complications of DMEK are approaching that of Descemet stripping automated endothelial keratoplasty.
authors.affiliation: Fort Myers, FL.
authors.forename: Mark S
authors.initials: MS
authors.lastname: Gorovoy
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D055954:Corneal Endothelial Cell Loss / Q000209:etiology; D003886:Descemet Membrane / Q000601:surgery; D057111:Descemet Stripping Endothelial Keratoplasty / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity