title: Rh(III)-catalyzed coupling of benzamides with propargyl alcohols via hydroarylation-lactonization.
abstract: Rh(III)-catalyzed C-H activation and annulation of 1-benzoylpyrrolidine with propargyl alcohols has been achieved for an efficient synthesis of (4-benzylidene)isochroman-1-one. Highly enantioenriched products were obtained starting from optically pure propargyl alcohols.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023, China.
authors.forename: Fen
authors.initials: F
authors.lastname: Wang
authors.forename: Zisong
authors.initials: Z
authors.lastname: Qi
authors.forename: Jiaqiong
authors.initials: J
authors.lastname: Sun
authors.forename: Xuelin
authors.initials: X
authors.lastname: Zhang
authors.forename: Xingwei
authors.initials: X
authors.lastname: Li
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001549:Benzamides / Q000737:chemistry*; D002384:Catalysis; D049934:Isocoumarins / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D020005:Propanols / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001549:Benzamides; D049934:Isocoumarins; D009942:Organometallic Compounds; D020005:Propanols; D012238:Rhodium; C028255:propargyl alcohol