title: Intraneural perineurioma of unilateral radial and median nerves manifesting with long-standing focal amyotrophy in a 14-year-old-boy.
abstract: Intraneural perineuriomas are rare tumors of the peripheral nerves with unique immunohistochemical findings. In this report, we highlight the clinical and imaging findings of an adolescent male with histologically proven intraneural perineurioma involving multiple nerves. The salient features included a clinically progressive course, imaging evidence of involvement of long segments of multiple nerves, enlargement of individual fascicles within the affected nerves, and intense contrast enhancement of the enlarged fascicles. The identification of enlarged fascicles with intense contrast enhancement within the affected and distended nerve segments may aid in distinguishing intraneural perineurioma from other tumors affecting the peripheral nerves.
authors.affiliation: Departments of *Neurology; †Neuropathology; and ‡Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India.
authors.forename: Madhu
authors.initials: M
authors.lastname: Nagappa
authors.forename: Yasha T
authors.initials: YT
authors.lastname: Chickabasaviah
authors.forename: Rose D
authors.initials: RD
authors.lastname: Bharath
authors.forename: Parayil S
authors.initials: PS
authors.lastname: Bindu
authors.forename: Sanjib
authors.initials: S
authors.lastname: Sinha
authors.forename: Arun B
authors.initials: AB
authors.lastname: Taly
mesh_terms: D000293:Adolescent; D020968:Brachial Plexus Neuritis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000473:pathology / Q000503:physiopathology*; D018317:Nerve Sheath Neoplasms / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D009431:Neural Conduction / Q000502:physiology*; D010524:Peripheral Nervous System Neoplasms / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D011826:Radial Nerve / Q000473:pathology / Q000503:physiopathology*