title: Recent advances in nanobiotechnology and high-throughput molecular techniques for systems biomedicine.
abstract: Nanotechnology-based tools are beginning to emerge as promising platforms for quantitative high-throughput analysis of live cells and tissues. Despite unprecedented progress made over the last decade, a challenge still lies in integrating emerging nanotechnology-based tools into macroscopic biomedical apparatuses for practical purposes in biomedical sciences. In this review, we discuss the recent advances and limitations in the analysis and control of mechanical, biochemical, fluidic, and optical interactions in the interface areas of nanotechnologybased materials and living cells in both in vitro and in vivo settings.
authors.affiliation: Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.
authors.forename: Eung-Sam
authors.initials: ES
authors.lastname: Kim
authors.forename: Eun Hyun
authors.initials: EH
authors.lastname: Ahn
authors.forename: Euiheon
authors.initials: E
authors.lastname: Chung
authors.forename: Deok-Ho
authors.initials: DH
authors.lastname: Kim
mesh_terms: D003952:Diagnostic Imaging / Q000379:methods; D057166:High-Throughput Screening Assays / Q000379:methods*; D006801:Humans; D062346:Molecular Medicine; D053758:Nanoparticles; D036103:Nanotechnology; D059010:Single-Cell Analysis; D049490:Systems Biology