title: Alterations in carbohydrate and protein metabolism in silver catfish (Rhamdia quelen) exposed to cadmium.
abstract: Changes in carbohydrate and protein metabolism were studied in silver catfish Rhamdia quelen exposed to cadmium (0; 0.236 or 0.414 mg/L) during 7 and 14 days. After exposure time the fish were exposed to recovery period (water without cadmium), during 7 and 14 days. Different alterations in the metabolic parameters were observed such as an increase in lactate, protein, amino acid and ammonia levels as well as a reduction in glucose values after the exposure periods in liver. In muscle, glycogen and glucose values enhanced after cadmium exposure at both concentrations for 7 days; however, at 0.414 mg/L cadmium, protein levels decreased while amino acids and ammonia levels enhanced. An increase in the lactate values was found in plasma after 7 days of exposure and a reduction in the lactate, glucose and protein levels occurred after 14 days of exposure. Results indicated that the metabolic alterations after cadmium exposure were dependent on the tissue type and exposure time. Cadmium exposure for 14 days and recovery period also of 14 days seem to be less harmful to the liver and muscle. However, even after recovering from some changes, fish health may be affected making them more sensitive to some environmental changes.
authors.affiliation: Adaptive Biochemistry Laboratory, Post-Graduation Program in Biological Science, Department of Chemistry, Federal University of Santa Maria (UFSM), Santa Maria, RS 97105-900, Brazil.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Pretto
authors.affiliation: Adaptive Biochemistry Laboratory, Post-Graduation Program in Biological Science, Department of Chemistry, Federal University of Santa Maria (UFSM), Santa Maria, RS 97105-900, Brazil. Electronic address: vania.loro@gmail.com.
authors.forename: Vania Lucia
authors.initials: VL
authors.lastname: Loro
authors.affiliation: Adaptive Biochemistry Laboratory, Post-Graduation Program in Biological Science, Department of Chemistry, Federal University of Santa Maria (UFSM), Santa Maria, RS 97105-900, Brazil.
authors.forename: Vera Maria
authors.initials: VM
authors.lastname: Morsch
authors.affiliation: Adaptive Biochemistry Laboratory, Post-Graduation Program in Biological Science, Department of Chemistry, Federal University of Santa Maria (UFSM), Santa Maria, RS 97105-900, Brazil.
authors.forename: Bibiana Silveira
authors.initials: BS
authors.lastname: Moraes
authors.affiliation: Adaptive Biochemistry Laboratory, Post-Graduation Program in Biological Science, Department of Chemistry, Federal University of Santa Maria (UFSM), Santa Maria, RS 97105-900, Brazil.
authors.forename: Charlene
authors.initials: C
authors.lastname: Menezes
authors.affiliation: Adaptive Biochemistry Laboratory, Post-Graduation Program in Biological Science, Department of Chemistry, Federal University of Santa Maria (UFSM), Santa Maria, RS 97105-900, Brazil.
authors.forename: Adriana
authors.initials: A
authors.lastname: Santi
authors.affiliation: Adaptive Biochemistry Laboratory, Post-Graduation Program in Biological Science, Department of Chemistry, Federal University of Santa Maria (UFSM), Santa Maria, RS 97105-900, Brazil.
authors.forename: Cândida
authors.initials: C
authors.lastname: Toni
mesh_terms: D000818:Animals; D029681:Arabidopsis Proteins; D002104:Cadmium / Q000633:toxicity*; D050260:Carbohydrate Metabolism / Q000187:drug effects*; D002397:Catfishes / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism; D019344:Lactic Acid / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D009132:Muscles / Q000187:drug effects / Q000378:metabolism; D009687:Nuclear Proteins; D011506:Proteins / Q000378:metabolism
chemical_list: D029681:Arabidopsis Proteins; D009687:Nuclear Proteins; D011506:Proteins; C523534:TIC protein, Arabidopsis; D002104:Cadmium; D019344:Lactic Acid; D006003:Glycogen; D005947:Glucose
keywords: Environmental contaminant; Exposure time; Fish; Fish health; Metabolic response