title: Management of placenta percreta: a review of published cases.
abstract: Publications on abnormally invasive placenta in general report what can be considered a mixture of the conditions true accreta, increta and percreta varieties. The aim of this review was to identify all published cases of the most severe condition, placenta percreta in order to describe complications associated with the three commonly used surgical strategies: local resection, hysterectomy or leaving the placenta in situ, and to describe the outcome, with respect to blood loss and transfusion requirements, with the different endovascular interventions that may be used as adjuncts in the management of the conditions. A PubMed search was performed in April 2013 and the final review included 119 published placenta percreta cases. Conservative management, where the placenta is left in situ for resorption, seems to be associated with severe long-term complications of hemorrhage and infections, including a 58% risk that a hysterectomy will eventually be needed up till nine months after the delivery. Local resection seems to be associated with fewer complications within 24 h postoperatively compared with hysterectomy or leaving the placenta in situ. A selection bias in the direction of less severe cases for the local resection technique might in part explain the lower complication rates with that approach. Future prospective data collection activities should include intended as well as actual management, and long-term follow-up of all cases is of vital importance.
authors.affiliation: Department of Cardiovascular Radiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
authors.forename: Caroline
authors.initials: C
authors.lastname: Clausen
authors.forename: Lars
authors.initials: L
authors.lastname: Lönn
authors.forename: Jens
authors.initials: J
authors.lastname: Langhoff-Roos
mesh_terms: D016063:Blood Loss, Surgical / Q000706:statistics & numerical data*; D001810:Blood Volume; D002585:Cesarean Section / Q000379:methods / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000706:statistics & numerical data*; D010921:Placenta Accreta / Q000473:pathology / Q000628:therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome; D055357:Uterine Artery Embolization / Q000706:statistics & numerical data*
keywords: Abnormally invasive placenta; cesarean hysterectomy; conservative treatment; local resection; placenta accreta; placenta percreta