title: Emotional prosody and diffusion tensor imaging in children after traumatic brain injury.
abstract: OBJECTIVE
  Brain structures and their white matter connections that may contribute to emotion processing and may be vulnerable to disruption by a traumatic brain injury (TBI) occurring in childhood have not been thoroughly explored.
  
  
  METHODS
  The current investigation examines the relationship between diffusion tensor imaging (DTI) metrics, including fractional anisotropy (FA) and apparent diffusion coefficient (ADC), and 3-month post-injury performance on a task of emotion prosody recognition and a control task of phonological discrimination in a group of 91 children who sustained either a moderate-to-severe TBI (n = 45) or orthopaedic injury (OI) (n = 46).
  
  
  RESULTS
  Brain-behaviour findings within OI participants confirmed relationships between several significant white matter tracts in emotional prosody performance (i.e. the cingulum bundle, genu of the corpus callosum, inferior longitudinal fasciculus (ILF) and the inferior fronto-occipital fasciculus (IFOF). The cingulum and genu were also related to phonological discrimination performance. The TBI group demonstrated few strong brain behaviour relationships, with significant findings emerging only in the cingulum bundle for Emotional Prosody and the genu for Phonological Processing.
  
  
  CONCLUSIONS
  The lack of clear relationships in the TBI group is discussed in terms of the likely disruption to cortical networks secondary to significant brain injuries.
authors.affiliation: Department of Psychology and Philosophy, Sam Houston State University , Huntsville, TX , USA .
authors.forename: Adam T
authors.initials: AT
authors.lastname: Schmidt
authors.forename: Gerri
authors.initials: G
authors.lastname: Hanten
authors.forename: Xiaoqi
authors.initials: X
authors.lastname: Li
authors.forename: Elisabeth A
authors.initials: EA
authors.lastname: Wilde
authors.forename: Alyssa P
authors.initials: AP
authors.lastname: Ibarra
authors.forename: Zili D
authors.initials: ZD
authors.lastname: Chu
authors.forename: Antonia R
authors.initials: AR
authors.lastname: Helbling
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Shah
authors.forename: Harvey S
authors.initials: HS
authors.lastname: Levin
mesh_terms: D000293:Adolescent; D016880:Anisotropy; D001930:Brain Injuries / Q000150:complications / Q000503:physiopathology / Q000523:psychology*; D001931:Brain Mapping; D002648:Child; D003072:Cognition Disorders / Q000209:etiology / Q000503:physiopathology / Q000523:psychology*; D038524:Diffusion Magnetic Resonance Imaging; D056324:Diffusion Tensor Imaging; D004644:Emotions; D005149:Facial Expression; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007398:Interpersonal Relations; D008297:Male; D009140:Musculoskeletal Diseases / Q000150:complications / Q000503:physiopathology / Q000523:psychology*; D009413:Nerve Fibers, Myelinated; D009483:Neuropsychological Tests; D021641:Recognition, Psychology; D012919:Social Behavior; D015599:Trauma Severity Indices