title: [Treatment of conjunctival melanoma].
abstract: METHODS
  The cases of an 86 year-old woman and a 61 year-old man with conjunctival pigmented tumors are presented. An excisional biopsy, conjunctival cryotherapy and amniotic membrane grafts were performed in both cases, along with the application of mitomycin-C in the postoperative period. The histology study confirmed the clinical suspicion of melanoma. Tolerance was good during the follow-up with no signs of recurrence in the last 12 and 6 months, respectively.
  
  
  CONCLUSIONS
  The recommended treatment for conjunctival melanoma is surgical removal with adjunctive therapies such as cryotherapy or topical mitomycin-C. This is a well tolerated therapy and effective for preventing recurrences in the short-medium term.
authors.affiliation: Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Principado de Asturias, España.
authors.forename: R
authors.initials: R
authors.lastname: Salazar Méndez
authors.affiliation: Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Principado de Asturias, España. Electronic address: baamonde@uniovi.es.
authors.forename: B
authors.initials: B
authors.lastname: Baamonde Arbaiza
authors.affiliation: Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Principado de Asturias, España.
authors.forename: P
authors.initials: P
authors.lastname: de la Roz Martín
authors.affiliation: Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Principado de Asturias, España.
authors.forename: T
authors.initials: T
authors.lastname: Parra Rodríguez
mesh_terms: D000369:Aged, 80 and over; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D003230:Conjunctival Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D017679:Cryotherapy; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D016685:Mitomycin / Q000627:therapeutic use; D012074:Remission Induction
chemical_list: D018906:Antineoplastic Agents, Alkylating; D016685:Mitomycin
keywords: Amniotic membrane; Biopsia; Biopsy; Cirugía; Conjunctival melanoma; Melanoma conjuntival; Membrana amniótica; Mitomicina C; Mitomycin-C; Surgery