title: Hematology and serum chemistry values of sooty mangabeys (Cercocebus atys): comparison with rhesus monkeys.
abstract: BACKGROUND
  The sooty mangabey is a vulnerable West African species that naturally harbors simian immunodeficiency virus (SIV) without pathological symptoms. We present normative hematology and serum chemistry values for this species.
  
  
  METHODS
  Hematology analytes from 136 females and 96 males and serum chemistry analytes from 57 females and 26 males were studied.
  
  
  RESULTS
  Values of several analytes fell outside published reference ranges in the rhesus monkey, a laboratory standard for Old World primates. Erythrocyte-related parameters were higher in mangabeys than in rhesus monkeys, while platelet counts were lower. Mangabeys also had higher gamma-glutamyltransferase levels and lower urea nitrogen levels. Males had higher erythrocyte-associated values than females. Albumin, globulin, albumin/globulin ratio, calcium, and creatinine changed with age in patterns similar to those reported for the rhesus monkey.
  
  
  CONCLUSIONS
  The unique blood profile of the mangabey should be taken into account in clinical and experimental studies of this species.
authors.affiliation: Division of Pathology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA; Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
authors.forename: P
authors.initials: P
authors.lastname: Sharma
authors.forename: L
authors.initials: L
authors.lastname: Chennareddi
authors.forename: E Z
authors.initials: EZ
authors.lastname: Greene-Hartsfield
authors.forename: F
authors.initials: F
authors.lastname: Villinger
authors.forename: J K
authors.initials: JK
authors.lastname: Cohen
authors.forename: J G
authors.initials: JG
authors.lastname: Herndon
mesh_terms: D000818:Animals; D001774:Blood Chemical Analysis; D016665:Cercocebus atys / Q000097:blood*; D005260:Female; D006403:Hematologic Tests; D008253:Macaca mulatta / Q000097:blood*; D008297:Male; D012016:Reference Values; D012737:Sex Factors
keywords: age; blood values; monkey; primate; sex