title: Managing benzodiazepine withdrawal during pregnancy: case-based guidelines.
abstract: Substance use disorders during pregnancy pose serious risks for both the mother and the fetus, demanding careful monitoring by the patient's medical providers. Sedative-hypnotic use, in particular, is common but remains poorly studied. Management of withdrawal from chronic benzodiazepine use during pregnancy presents unique challenges to the treating physician. We present two pregnant patients with dependence on sedative-hypnotic agents, outline principles of benzodiazepine withdrawal, and suggest guidelines for detoxification during pregnancy.
authors.affiliation: Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3520 Fifth Ave., Keystone Building, Lower Level Suite 1, Pittsburgh, PA, 15213, USA, gopalanpr@upmc.edu.
authors.forename: Priya
authors.initials: P
authors.lastname: Gopalan
authors.forename: Jody B
authors.initials: JB
authors.lastname: Glance
authors.forename: Pierre N
authors.initials: PN
authors.lastname: Azzam
mesh_terms: D000328:Adult; D001569:Benzodiazepines / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects*; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011256:Pregnancy Outcome; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy / Q000628:therapy*; D019966:Substance-Related Disorders / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D006993:Hypnotics and Sedatives; D001569:Benzodiazepines