title: A Case of Teicoplanin-Induced Pancytopenia Caused by Excessive Dosing.
abstract: Teicoplanin is reported to be as effective as vancomycin but with minimal side effects. We report a case of teicoplanin-induced pancytopenia, which has not been demonstrated previously. A 44-year-old man with tetraplegia was treated with a diagnosis of urinary tract infection and pneumonia, and a high-dose of teicoplanin (400 mg every 12 hours) was administered for 4 days inadvertently. Although the infection rapidly improved, the patient developed pancytopenia by the fourth day of teicoplanin therapy, which was improved after reducing the dose of teicoplanin (200 mg/d). Our patient represents a probable case of teicoplanin-induced pancytopenia with adverse drug reaction probability score of 6.
authors.affiliation: Departments of 1Internal Medicine, 2Laboratory Medicine, and 3Surgery, Korea Workers' Compensation & Welfare Hospital, Incheon, Korea.
authors.forename: Hye Min
authors.initials: HM
authors.lastname: Choi
authors.forename: Moon Hee
authors.initials: MH
authors.lastname: Choi
authors.forename: Yoo Whooi
authors.initials: YW
authors.lastname: Yang
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D062787:Drug Overdose / Q000150:complications*; D006801:Humans; D008297:Male; D010198:Pancytopenia / Q000139:chemically induced*; D017334:Teicoplanin / Q000009:adverse effects*
chemical_list: D000900:Anti-Bacterial Agents; D017334:Teicoplanin