title: One-stage full-mouth disinfection combined with a periodontal dressing: a randomized controlled clinical trial.
abstract: OBJECTIVE
  To compare the clinical benefit of a periodontal dressing applied after a one-stage full-mouth disinfection (OSFMD) in patients with chronic periodontitis up to 3 months after therapy.
  
  
  METHODS
  This randomized, controlled split-mouth study included 24 patients. After OSFMD, a test and a control side were selected by means of a computer-generated randomization list. Test sides received a periodontal dressing (Coepak(®) ) for 7 days and the control sides received no periodontal dressing. After 7 days the periodontal dressing was removed and the pain experience was recorded. After 3 months, the clinical periodontal parameters were recorded.
  
  
  RESULTS
  The periodontal dressing group showed a significant (p < 0.05) additional pocket depth reduction and additional clinical attachment gain for the moderate pockets of single- and multi-rooted teeth compared with the control group. A significant (p < 0.05) lower percentage of sites with probing pocket depth ≥5 mm were shown for the periodontal dressing group compared with the control group (2.7 ± 16.3% versus 4.8 ± 21.4%). The pain intensity was significantly reduced when using a periodontal dressing (5.13 ± 0.89 versus 3.42 ± 1.27).
  
  
  CONCLUSIONS
  The use of a periodontal dressing for 7 days after a OSFMD offers an additional short-term clinical improvement and lowers the pain intensity.
authors.affiliation: Department of Periodontology, School of Dentistry, Oral Pathology & Maxillo-facial Surgery, Faculty of Medicine, Catholic University Leuven, Leuven, Belgium.
authors.forename: Johan A J
authors.initials: JA
authors.lastname: Keestra
authors.forename: Wim
authors.initials: W
authors.lastname: Coucke
authors.forename: Marc
authors.initials: M
authors.lastname: Quirynen
mesh_terms: D000328:Adult; D000368:Aged; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D002710:Chlorhexidine / Q000627:therapeutic use; D055113:Chronic Periodontitis / Q000145:classification / Q000628:therapy*; D003774:Dental Plaque Index; D012534:Dental Scaling / Q000379:methods*; D005500:Follow-Up Studies; D005889:Gingival Recession / Q000145:classification / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D009910:Oral Hygiene / Q000193:education; D010147:Pain Measurement / Q000379:methods; D017622:Periodontal Attachment Loss / Q000145:classification / Q000628:therapy; D010511:Periodontal Dressings; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000145:classification / Q000628:therapy; D016745:Root Planing / Q000379:methods*
chemical_list: D000891:Anti-Infective Agents, Local; D002710:Chlorhexidine
keywords: chronic periodontitis; full-mouth disinfection; non-surgical therapy; periodontal dressing