title: Mushroom intake and risk of epithelial ovarian cancer in southern Chinese women.
abstract: OBJECTIVE
  This study aimed to investigate the association between mushroom consumption and risk of epithelial ovarian cancer in southern Chinese women.
  
  
  METHODS
  A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, from 2006 to 2008. Participants were 500 incident patients with epithelial ovarian cancer and 500 controls, with a mean (SD) age of 59 (6) years. Information on habitual mushroom consumption was obtained by face-to-face interview using a validated and reliable food frequency questionnaire. Unconditional logistic regression analyses were performed to assess the association between mushroom intake and the ovarian cancer risk.
  
  
  RESULTS
  The patients with ovarian cancer consumed less mushrooms (mean [SD], 28.48 [37.45] g/d) than did controls (mean [SD], 30.75 [41.85] g/d). Apparent reductions in cancer risk were found at high levels of intake, especially for the common white button mushroom with adjusted odds ratios 0.68 (95% confidence interval, 0.52-0.89) for women consuming more than 2 g per day relative to those who consume less than that (P = 0.005). Decreases in risk at high levels of intake were also observed for serous and mucinous subtypes of epithelial ovarian tumors.
  
  
  CONCLUSIONS
  Intake of mushrooms, particularly white button mushroom, seemed to be inversely associated with the incidence of epithelial ovarian cancer in southern Chinese women.
authors.affiliation: *School of Public Health, Curtin University, Perth, Australia; and †Department of Community Health and Network Coordination, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
authors.forename: Andy H
authors.initials: AH
authors.lastname: Lee
authors.forename: Maria
authors.initials: M
authors.lastname: Pasalich
authors.forename: Dada
authors.initials: D
authors.lastname: Su
authors.forename: Li
authors.initials: L
authors.lastname: Tang
authors.forename: Van Dinh
authors.initials: VD
authors.lastname: Tran
authors.forename: Colin W
authors.initials: CW
authors.lastname: Binns
mesh_terms: D000363:Agaricales; D000368:Aged; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D003536:Cystadenocarcinoma / Q000208:ethnology* / Q000517:prevention & control; D005260:Female; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000208:ethnology* / Q000517:prevention & control