title: The impact of laparoscopic cystectomy on ovarian reserve in patients with unilateral and bilateral endometriomas.
abstract: OBJECTIVE
  To evaluate the effects of laparoscopic cystectomy on ovarian reserve in patients with endometriomas.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  Private and university hospitals.
  
  
  METHODS
  A total of 193 patients with endometriomas undergoing laparoscopic cyctectomy.
  
  
  METHODS
  Serum levels of antimüllerian hormone (AMH), FSH, and E₂, as well as antral follicle count (AFC) were measured preoperatively and 1 week, 3 and 9 months postoperatively for AMH, and 3 months for other values.
  
  
  METHODS
  Ovarian reserve based on the comparison of AMH alterations. The secondary end points are changes in FSH, E₂, and AFC.
  
  
  RESULTS
  Serum AMH level decreased significantly from the baseline (3.86 ± 3.58 ng/mL) to 1 week (1.66 ± 1.92 ng/mL), 3 months (2.06 ± 2.5 ng/mL), and 9 months (1.77 ± 1.76 ng/mL) postoperatively. Those patients with bilateral endometriomas had significantly lower levels of AMH, 1 week, 3 and 9 months after operation. Also, patients older than 38 years had lower postoperative AMH levels. The FSH levels increased significantly from baseline to 3 months postoperatively. The AFC level increased significantly from baseline to 3 months after operation.
  
  
  CONCLUSIONS
  The AMH level decreased and the FSH level increased after laparoscopic cystectomy for endometriomas, especially in older patients and those with bilateral cysts.
authors.affiliation: Department of Obstetrics and Gynecology, Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: alborzis@sums.ac.ir.
authors.forename: Saeed
authors.initials: S
authors.lastname: Alborzi
authors.affiliation: Department of Obstetrics and Gynecology, Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Pegah
authors.initials: P
authors.lastname: Keramati
authors.affiliation: Department of Obstetrics and Gynecology, Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Masoomeh
authors.initials: M
authors.lastname: Younesi
authors.affiliation: Department of Obstetrics and Gynecology, Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Alamtaj
authors.initials: A
authors.lastname: Samsami
authors.affiliation: Department of Obstetrics and Gynecology, Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Nasrin
authors.initials: N
authors.lastname: Dadras
mesh_terms: D000293:Adolescent; D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood; D015415:Biomarkers / Q000097:blood; D004715:Endometriosis / Q000097:blood* / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D010048:Ovarian Cysts / Q000097:blood* / Q000175:diagnosis / Q000601:surgery*; D006080:Ovarian Follicle / Q000378:metabolism*; D010053:Ovary / Q000378:metabolism; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D015415:Biomarkers; D054304:Anti-Mullerian Hormone
keywords: Laparoscopic cystectomy; endometrioma; ovarian reserve