title: New strigolactone analogs as plant hormones with low activities in the rhizosphere.
abstract: Strigolactones (SLs) are known not only as plant hormones, but also as rhizosphere signals for establishing symbiotic and parasitic interactions. The design of new specific SL analogs is a challenging goal in understanding the basic plant biology and is also useful to control plant architectures without favoring the development of parasitic plants. Two different molecules (23 (3'-methyl-GR24), 31 (thia-3'-methyl-debranone-like molecule)) already described, and a new one (AR36), for which the synthesis is presented, are biologically compared with the well-known GR24 and the recently identified CISA-1. These different structures emphasize the wide range of parts attached to the D-ring for the bioactivity as a plant hormone. These new compounds possess a common dimethylbutenolide motif but their structure varies in the ABC part of the molecules: 23 has the same ABC part as GR24, while 31 and AR36 carry, respectively, an aromatic ring and an acyclic carbon chain. Detailed information is given for the bioactivity of such derivatives in strigolactone synthesis or in perception mutant plants (pea rms1 and rms4, Arabidopsis max2 and, max4) for different hormonal functions along with their action in the rhizosphere on arbuscular mycorrhizal hyphal growth and parasitic weed germination.
authors.affiliation: Institut Jean-Pierre Bourgin, UMR1318 Institut National de la Recherche Agronomique (INRA)-AgroParisTech, Route de Saint-Cyr (RD 10), F-78026 Versailles Cedex, France.
authors.forename: François-Didier
authors.initials: FD
authors.lastname: Boyer
authors.forename: Alexandre
authors.initials: A
authors.lastname: de Saint Germain
authors.forename: Jean-Bernard
authors.initials: JB
authors.lastname: Pouvreau
authors.forename: Guillaume
authors.initials: G
authors.lastname: Clavé
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Pillot
authors.forename: Amélie
authors.initials: A
authors.lastname: Roux
authors.forename: Amanda
authors.initials: A
authors.lastname: Rasmussen
authors.forename: Stephen
authors.initials: S
authors.lastname: Depuydt
authors.forename: Dominique
authors.initials: D
authors.lastname: Lauressergues
authors.forename: Nicolas
authors.initials: N
authors.lastname: Frei Dit Frey
authors.forename: Thomas S A
authors.initials: TS
authors.lastname: Heugebaert
authors.forename: Christian V
authors.initials: CV
authors.lastname: Stevens
authors.forename: Danny
authors.initials: D
authors.lastname: Geelen
authors.forename: Sofie
authors.initials: S
authors.lastname: Goormachtig
authors.forename: Catherine
authors.initials: C
authors.lastname: Rameau
mesh_terms: D017360:Arabidopsis / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D055137:Glomeromycota / Q000378:metabolism; D007783:Lactones / Q000378:metabolism*; D010937:Plant Growth Regulators / Q000378:metabolism*; D058441:Rhizosphere
chemical_list: D007783:Lactones; D010937:Plant Growth Regulators
keywords: Arabidopsis; Gigaspora rosea; Pisum sativum; plant growth regulator.; root parasitic plants; strigolactones; synthetic analogs