title: Future trends for unicompartmental arthritis of the knee: injectables & stem cells.
abstract: Arthritis is one of the most frequent musculoskeletal problems, causing pain, disability, and a significant economic burden. In this article, we discuss current nonsurgical injectable treatment options as well as future trends for cartilage lesions and early arthritis of the knee. We cover some potential treatments for knee osteoarthritis, including stem cell and gene therapies.
authors.affiliation: Department of Orthopedic Surgery and Traumatology, University of São Paulo, Rua Ouvidio Pires de Campos, 333 São Paulo, SP 05403-010, Brazil; Hospital for Special Surgery, Weil Cornell Medical College, 535 E 70th Street, New York, NY 10021, USA.
authors.forename: Marco Kawamura
authors.initials: MK
authors.lastname: Demange
authors.forename: Marco
authors.initials: M
authors.lastname: Sisto
authors.forename: Scott
authors.initials: S
authors.lastname: Rodeo
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D015316:Genetic Therapy / Q000379:methods / Q000639:trends*; D006801:Humans; D006820:Hyaluronic Acid / Q000627:therapeutic use; D007270:Injections, Intra-Articular; D036341:Intercellular Signaling Peptides and Proteins / Q000627:therapeutic use*; D020370:Osteoarthritis, Knee / Q000628:therapy*; D053657:Platelet-Rich Plasma; D033581:Stem Cell Transplantation / Q000379:methods / Q000639:trends*; D055676:Viscosupplementation / Q000379:methods / Q000639:trends*; D055675:Viscosupplements / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D036341:Intercellular Signaling Peptides and Proteins; D055675:Viscosupplements; D006820:Hyaluronic Acid
keywords: Arthritis; Hyaluronic acid; Injectable arthritis treatment; Knee arthritis; Osteoarthritis; Stem cell