title: Type a niemann-pick disease. Description of three cases with delayed myelination.
abstract: We describe three patients with type A Niemann-Pick disease (NPD-A). NPD-A is an autosomal recessive neuronal storage disease classified among the sphingolipidoses, characterized by accumulation of sphingomyelin in various tissues and in the brain. Magnetic Resonance imaging (MRI) of our three patients showed a marked delay of myelination with frontal atrophy. Few descriptions of this MRI pattern of delayed myelination have been published to date.
authors.affiliation: Unit of Neuroradiology, "Federico II" University, Naples - ferdinandocaranci@libero.it.
authors.forename: A
authors.initials: A
authors.lastname: D'Amico
authors.forename: M
authors.initials: M
authors.lastname: Sibilio
authors.forename: F
authors.initials: F
authors.lastname: Caranci
authors.forename: F
authors.initials: F
authors.lastname: Bartiromo
authors.forename: R
authors.initials: R
authors.lastname: Taurisano
authors.forename: F
authors.initials: F
authors.lastname: Balivo
authors.forename: D
authors.initials: D
authors.lastname: Melis
authors.forename: G
authors.initials: G
authors.lastname: Parenti
authors.forename: S
authors.initials: S
authors.lastname: Cirillo
authors.forename: R
authors.initials: R
authors.lastname: Elefante
authors.forename: A
authors.initials: A
authors.lastname: Brunetti