title: Protamine-adsorbed magnetic nanoparticles for efficient isolation and concentration of hepatitis-C virus from human plasma samples.
abstract: Protamine hydrochloride adsorbed onto citrated superparamagnetic iron oxide nanoparticles represents an efficient tool for capturing and concentration of hepatitis-C virus from plasma samples, improving the sensitivity of downstream analysis by nucleic acid testing.
authors.affiliation: Institute for Exp. Haematology and Transfusion Medicine, University of Bonn Medical Centre, Bonn, Germany. jens.mueller@ukb.uni-bonn.de a.yassin@daad-alumni.de.
authors.forename: Abdallah A
authors.initials: AA
authors.lastname: Yassin
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: Elwaseef
authors.forename: Magdy M
authors.initials: MM
authors.lastname: Elnashar
authors.forename: Johannes
authors.initials: J
authors.lastname: Oldenburg
authors.forename: Günter
authors.initials: G
authors.lastname: Mayer
authors.forename: Bernd
authors.initials: B
authors.lastname: Pötzsch
authors.forename: Jens
authors.initials: J
authors.lastname: Müller
mesh_terms: D000327:Adsorption; D003911:Dextrans / Q000737:chemistry; D016174:Hepacivirus / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D011479:Protamines / Q000737:chemistry*; D012367:RNA, Viral / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013917:Thrombin / Q000737:chemistry / Q000378:metabolism
chemical_list: D003911:Dextrans; D058185:Magnetite Nanoparticles; D011479:Protamines; D012367:RNA, Viral; D013917:Thrombin; C065507:ferumoxides