title: Central nervous system toxicity.
abstract: Central nervous system toxicity caused by xenobiotic exposure is a common reason for presentation to the emergency department. Sources of exposure may be medicinal, recreational, environmental, or occupational; the means of exposure may be intentional or unintended. Toxicity may manifest as altered thought content resulting in psychosis or confusion; may affect arousal, resulting in lethargy, stupor, or coma; or may affect both elements of consciousness. Seizures may also occur.
authors.affiliation: Department of Medical Toxicology, Banner Good Samaritan Medical Center, Center for Toxicology and Pharmacology Education and Research, University of Arizona College of Medicine, 925 East McDowell Road, Phoenix, AZ 85006, USA. Electronic address: Michelle.ruha@bannerhealth.com.
authors.forename: Anne-Michelle
authors.initials: AM
authors.lastname: Ruha
authors.forename: Michael
authors.initials: M
authors.lastname: Levine
mesh_terms: D002493:Central Nervous System Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D004632:Emergency Medical Services; D006801:Humans; D055553:Prescription Drugs / Q000009:adverse effects*; D015262:Xenobiotics / Q000633:toxicity*
chemical_list: D055553:Prescription Drugs; D015262:Xenobiotics
keywords: Agitated delirium; Altered mental status; CNS depression; CNS toxicity; Drug-induced seizures