title: Severe vitamin D deficiency in a patient with sickle cell disease: a case study with literature review.
abstract: OBJECTIVE
  Vitamin D is essential for the normal absorption of calcium and to maintain calcium homeostasis. Vitamin D deficiency results in rickets, osteomalacia, and bony changes in the spine. Sickle cell disease patients are at an increased risk of vitamin D deficiency.
  
  
  METHODS
  We describe a case of severe vitamin D deficiency and response to vitamin D supplementation in a patient with sickle cell disease.
  
  
  CONCLUSIONS
  Currently, there are no recommendations for calcium and vitamin D supplementation in sickle cell patients. Vitamin D deficiency in these patients may be due to poor absorption.
authors.affiliation: *Pediatric Resident †Department of Hematology and Oncology, Bronx Lebanon Hospital, Bronx, NY.
authors.forename: Poonam L
authors.initials: PL
authors.lastname: Kaza
authors.forename: Thomas
authors.initials: T
authors.lastname: Moulton
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000097:blood / Q000150:complications / Q000188:drug therapy; D006801:Humans; D008297:Male; D014807:Vitamin D / Q000008:administration & dosage*; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications / Q000188:drug therapy; D014815:Vitamins / Q000008:administration & dosage*
chemical_list: D014815:Vitamins; D014807:Vitamin D