title: A graphical user interface for infant ERP analysis.
abstract: Recording of event-related potentials (ERPs) is one of the best-suited technologies for examining brain function in human infants. Yet the existing software packages are not optimized for the unique requirements of analyzing artifact-prone ERP data from infants. We developed a new graphical user interface that enables an efficient implementation of a two-stage approach to the analysis of infant ERPs. In the first stage, video records of infant behavior are synchronized with ERPs at the level of individual trials to reject epochs with noncompliant behavior and other artifacts. In the second stage, the interface calls MATLAB and EEGLAB (Delorme & Makeig, Journal of Neuroscience Methods 134(1):9-21, 2004) functions for further preprocessing of the ERP signal itself (i.e., filtering, artifact removal, interpolation, and rereferencing). Finally, methods are included for data visualization and analysis by using bootstrapped group averages. Analyses of simulated and real EEG data demonstrated that the proposed approach can be effectively used to establish task compliance, remove various types of artifacts, and perform representative visualizations and statistical comparisons of ERPs. The interface is available for download from http://www.uta.fi/med/icl/methods/eeg.html in a format that is widely applicable to ERP studies with special populations and open for further editing by users.
authors.affiliation: Tampere Center for Child Health Research, University of Tampere School of Medicine, 33014, Tampere, Finland.
authors.forename: Jussi
authors.initials: J
authors.lastname: Kaatiala
authors.forename: Santeri
authors.initials: S
authors.lastname: Yrttiaho
authors.forename: Linda
authors.initials: L
authors.lastname: Forssman
authors.forename: Katherine
authors.initials: K
authors.lastname: Perdue
authors.forename: Jukka
authors.initials: J
authors.lastname: Leppänen
mesh_terms: D000465:Algorithms; D016477:Artifacts; D001519:Behavior; D003196:Computer Graphics; D003198:Computer Simulation; D004569:Electroencephalography / Q000379:methods; D005071:Evoked Potentials / Q000502:physiology*; D005133:Eye Movements / Q000502:physiology; D006801:Humans; D007223:Infant; D015588:Observer Variation; D012815:Signal Processing, Computer-Assisted; D012984:Software; D014584:User-Computer Interface; D014741:Video Recording