title: Knitting up the raveled sleave of care.
abstract: This Review is based on the Franklin Epstein Lecture delivered at Beth Israel Deaconess Hospital on 25 April 2013. We discuss recent advances in our understanding of molecular clocks and highlight their relevance to human physiology and disease.
authors.affiliation: Institute for Translational Medicine and Therapeutics, Smilow Center for Translational Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
authors.forename: Guangrui
authors.initials: G
authors.lastname: Yang
authors.forename: Georgios
authors.initials: G
authors.lastname: Paschos
authors.forename: Anne M
authors.initials: AM
authors.lastname: Curtis
authors.forename: Erik S
authors.initials: ES
authors.lastname: Musiek
authors.forename: Sarah C
authors.initials: SC
authors.lastname: McLoughlin
authors.forename: Garret A
authors.initials: GA
authors.lastname: FitzGerald
mesh_terms: D000375:Aging; D002320:Cardiovascular Physiological Phenomena; D002940:Circadian Rhythm; D006801:Humans; D007109:Immunity; D007249:Inflammation / Q000503:physiopathology; D008660:Metabolism; D009369:Neoplasms / Q000276:immunology / Q000503:physiopathology