title: [The predictive value of admission hyperglycemia in hospital and long-term mortality of diabetics versus non-diabetics with acute coronary syndrome].
abstract: OBJECTIVE
  To evaluate whether the predictive value of admission hyperglycemia for mortality differs between diabetics and non-diabetics with acute coronary syndrome (ACS).
  
  
  METHODS
  A total of 1534 consecutive patients admitted with ACS to Central Control Unit of Beijing Friendship Hospital were analyzed. Among these patients, 1332 patients who had a venous plasma glucose record at admission were retrospectively enrolled and were stratified according to admission glucose levels with or without diabetes. The primary end point was in-hospital and 2-year all-cause mortality.
  
  
  RESULTS
  In patients without a history of diabetes, 649 patients had glucose level ≤ 7.8 mmol/L(group A), 204 patients with 7.8-11.0 mmol/L (group B) and 142 patients > 11.0 mmol/L (group C). Of those with diabetes, 124 patients were in group A, 142 in group B and 126 in group C. By Cox regression analysis, admission hyperglycemia (group B, HR 1.48, P = 0.05; group C, HR 2.78, P < 0.001) was an independent predictor of long-term all-cause mortality in patients without diabetes. In patients with diabetes, blood glucose > 11.0 mmol/L (group C, HR 2.68, P < 0.001) also independently predicted long-term all-cause mortality.
  
  
  CONCLUSIONS
  Compared with the diabetic patients, elevation of blood glucose at admission is common in ACS patients without definite history of diabetes. Admission hyperglycemia should be considered as a risk factor strongly correlated with in-hospital and 2-year all-cause mortality in patients with ACS.
authors.affiliation: Department of Cardiology, Beijing Friendship Hospital, Capital Medical University,Beijing 100050, China.
authors.forename: Hui-fen
authors.initials: HF
authors.lastname: Song
authors.forename: Hong-wei
authors.initials: HW
authors.lastname: Li
authors.forename: Shu-me
authors.initials: SM
authors.lastname: Zhao
authors.forename: Su
authors.initials: S
authors.lastname: Wang
authors.forename: Xiao-hui
authors.initials: XH
authors.lastname: Li
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000150:complications / Q000401:mortality*; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000097:blood*; D005260:Female; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D001786:Blood Glucose