title: Analysis of 15 autosomal STR loci from Mar del Plata and Bahia Blanca (Central Region of Argentina).
abstract: Allele frequencies for the 15 short tandem repeats (STRs) loci included in the AmpFlSTR® Identifiler kit were estimated in a sample of unrelated individuals from Mar del Plata (MDQ; N = 180) and Bahia Blanca (BB; N = 85) (Buenos Aires, Argentina). Biological samples were obtained from voluntary donors and forensic cases. Both populations were in Hardy-Weinberg equilibrium after Bonferroni correction, except for locus vWA in MDQ and D2S1338 in BB. FGA was the most informative locus, and the least discriminating locus was TPOX in both samples. The combined power of discrimination (PDc) and the combined probability of exclusion (PEc) were similar in MDQ and BB samples (0.999999998 < PDc < 0.999999999 and 0.999999979 < PEc < 0.999999989). The multidimentional scaling plot from Rst genetic distance matrix and the interethnic admixture estimation supported a higher European contribution in populations of the central region compared with populations from other regions of Argentina with higher Amerindian composition. These results enlarge the Argentine databases of autosomal STR loci, revealed as an excellent tool for human identification tests and population genetic analysis.
authors.affiliation: Unidad de Diversidad, Sistemática y Evolución, Laboratorio de Biologia Molecular, Centro Nacional Patagonico-CONICET, Bvd. Brown 2915, Puerto Madryn, Chubut, Argentina, parolin@cenpat.edu.ar.
authors.forename: María Laura
authors.initials: ML
authors.lastname: Parolin
authors.forename: Robert
authors.initials: R
authors.lastname: Carreras-Torres
authors.forename: Lorena Andrea
authors.initials: LA
authors.lastname: Sambuco
authors.forename: Stella Maris
authors.initials: SM
authors.lastname: Jaureguiberry
authors.forename: Celia Estela
authors.initials: CE
authors.lastname: Iudica
mesh_terms: D001118:Argentina; D016172:DNA Fingerprinting; D005006:Ethnicity / Q000235:genetics; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction