title: [Hand involvement in systemic sclerosis].
abstract: Hand involvement is very common in patients with systemic sclerosis and represents an important tool for the early diagnosis of the disease. Vascular involvement of the hands is at the forefront of systemic sclerosis, with Raynaud's phenomenon, which may be complicated by digital ulcers, digital necrosis causing pain, infection and significant disability. Joint inflammation can also be disabling and causes the occurrence of contractures and deformities resulting in a marked hand disability. Skin sclerosis involving fingers and hands leads to the occurrence of pain and functional impairment. Hand involvement contributes to 75 % of global disability in patients with systemic sclerosis. Only a comprehensive care, taking into account the vascular, skin and joint manifestations, including physical therapy if needed can improve hand function in patients with systemic sclerosis.
authors.affiliation: Assistance publique-Hôpitaux de Paris, hôpital Cochin, université Paris Descartes, centre de référence pour les vascularites nécrosantes et la sclérodermie systémique, service de médecine interne, 27, rue du Faubourg-Saint-Jacques, 75679 Paris cedex 14, France. Electronic address: luc.mouthon@cch.aphp.fr.
authors.forename: Luc
authors.initials: L
authors.lastname: Mouthon
mesh_terms: D004185:Disability Evaluation; D006233:Persons with Disabilities; D005385:Fingers / Q000098:blood supply; D006225:Hand / Q000098:blood supply / Q000503:physiopathology*; D006229:Hand Dermatoses / Q000209:etiology / Q000628:therapy; D006801:Humans; D011928:Raynaud Disease / Q000150:complications; D012595:Scleroderma, Systemic / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D012883:Skin Ulcer / Q000175:diagnosis / Q000209:etiology