title: Molecular pathology in transfusion medicine.
abstract: This article provides an overview of the application of molecular diagnostic methods to red cell and platelet compatibility testing. The advantages and limitations of molecular methods are evaluated compared with traditional serologic methods. The molecular bases of clinically significant red cell and platelet antigens are presented. Current recommendations for reporting molecular assay results and distinctions between genotype and phenotype are discussed.
authors.affiliation: Department of Pathology, Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA. Electronic address: ElkinsM@upstate.edu.
authors.forename: Matthew B
authors.initials: MB
authors.lastname: Elkins
authors.forename: Robertson D
authors.initials: RD
authors.lastname: Davenport
authors.forename: Barbara A
authors.initials: BA
authors.lastname: O'Malley
authors.forename: Martin H
authors.initials: MH
authors.lastname: Bluth
mesh_terms: D006801:Humans; D057089:Pathology, Molecular; D064826:Transfusion Medicine
keywords: Antibody; Antigen; Blood donors; Genotype; Phenotype; Platelets; Red blood cells; Serology; Transfusion