title: Biomechanical determinants of the stability of dental implants: influence of the bone-implant interface properties.
abstract: Dental implants are now widely used for the replacement of missing teeth in fully or partially edentulous patients and for cranial reconstructions. However, risks of failure, which may have dramatic consequences, are still experienced and remain difficult to anticipate. The stability of biomaterials inserted in bone tissue depends on multiscale phenomena of biomechanical (bone-implant interlocking) and of biological (mechanotransduction) natures. The objective of this review is to provide an overview of the biomechanical behavior of the bone-dental implant interface as a function of its environment by considering in silico, ex vivo and in vivo studies including animal models as well as clinical studies. The biomechanical determinants of osseointegration phenomena are related to bone remodeling in the vicinity of the implants (adaptation of the bone structure to accommodate the presence of a biomaterial). Aspects related to the description of the interface and to its space-time multiscale nature will first be reviewed. Then, the various approaches used in the literature to measure implant stability and the bone-implant interface properties in vitro and in vivo will be described. Quantitative ultrasound methods are promising because they are cheap, non invasive and because of their lower spatial resolution around the implant compared to other biomechanical approaches.
authors.affiliation: Université Paris-Est, Laboratoire Modélisation et Simulation Multi Echelle, UMR CNRS 8208, 61 avenue du Général de Gaulle, 94010 Créteil cedex, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Mathieu
authors.affiliation: Université Paris-Est, Laboratoire Modélisation et Simulation Multi Echelle, UMR CNRS 8208, 61 avenue du Général de Gaulle, 94010 Créteil cedex, France.
authors.forename: Romain
authors.initials: R
authors.lastname: Vayron
authors.affiliation: Septodont, 58 Rue Pont de Créteil, 94100 Saint-Maur-des-Fossés, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Richard
authors.affiliation: Septodont, 58 Rue Pont de Créteil, 94100 Saint-Maur-des-Fossés, France.
authors.forename: Grégory
authors.initials: G
authors.lastname: Lambert
authors.affiliation: Université Paris-Est, Laboratoire Modélisation et Simulation Multi Echelle, UMR CNRS 8208, 61 avenue du Général de Gaulle, 94010 Créteil cedex, France.
authors.forename: Salah
authors.initials: S
authors.lastname: Naili
authors.affiliation: Service de Chirurgie Plastique, Reconstructrice et Esthétique, CHU H. Mondor, 94017 Créteil cedex, France.
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Meningaud
authors.affiliation: CNRS, Laboratoire Modélisation et Simulation Multi Echelle, UMR CNRS 8208, 61 avenue du Général de Gaulle, 94010 Créteil cedex, France. Electronic address: guillaume.haiat@univ-paris-est.fr.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Haiat
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D001696:Biomechanical Phenomena; D016723:Bone Remodeling; D015921:Dental Implants; D017267:Dental Prosthesis Design; D006801:Humans; D016348:Osseointegration; D014463:Ultrasonography / Q000379:methods*
chemical_list: D001672:Biocompatible Materials; D015921:Dental Implants
keywords: Biomechanical properties; Bone; Implant; Osseointegration; Stability