title: Immunology on chip: promises and opportunities.
abstract: Microfluidics has facilitated immunological studies by enhancing speed, efficiency and sensitivity of current analysis methods. It offers miniaturization of current laboratory equipment, and enables analysis of clinical samples without the need for sophisticated infrastructure. More importantly, microfluidics offers unique capabilities; including conducting multiple serial or parallel tasks as well as providing complex and precisely controlled environmental conditions that are not achievable using conventional laboratory equipment. Microfluidics is a promising technology for fundamental and applied immunological studies, allowing generation of high throughput, robust and portable platforms, opening a new area of automation in immunology.
authors.affiliation: School of Electrical and Computer Engineering, RMIT University, Melbourne, Australia; Health Innovations Research Institute, RMIT University, Melbourne, Australia. Electronic address: sara.baratchi@rmit.edu.au.
authors.forename: Sara
authors.initials: S
authors.lastname: Baratchi
authors.affiliation: School of Electrical and Computer Engineering, RMIT University, Melbourne, Australia.
authors.forename: Khashayar
authors.initials: K
authors.lastname: Khoshmanesh
authors.affiliation: Skirball Institute of Biomolecular Medicine, New York University, School of Medicine, NewYork, USA.
authors.forename: Catarina
authors.initials: C
authors.lastname: Sacristán
authors.affiliation: Skirball Institute of Biomolecular Medicine, New York University, School of Medicine, NewYork, USA.
authors.forename: David
authors.initials: D
authors.lastname: Depoil
authors.affiliation: BioMEMS Research Group, School of Applied Sciences, RMIT University, Melbourne, Australia.
authors.forename: Donald
authors.initials: D
authors.lastname: Wlodkowic
authors.affiliation: Health Innovations Research Institute, RMIT University, Melbourne, Australia.
authors.forename: Peter
authors.initials: P
authors.lastname: McIntyre
authors.affiliation: School of Electrical and Computer Engineering, RMIT University, Melbourne, Australia. Electronic address: arnan.mitchell@rmit.edu.au.
authors.forename: Arnan
authors.initials: A
authors.lastname: Mitchell
mesh_terms: D000818:Animals; D002460:Cell Line; D002469:Cell Separation; D006801:Humans; D007118:Immunoassay; D056656:Lab-On-A-Chip Devices; D046210:Microfluidic Analytical Techniques; D009696:Nucleic Acids / Q000032:analysis; D011506:Proteins / Q000032:analysis
chemical_list: D009696:Nucleic Acids; D011506:Proteins
keywords: Immunoassays; Immunology; Lab on a chip; Microfluidics