title: Malocclusion and treatment need in children and adolescents with sickle cell disease.
abstract: OBJECTIVE
  To assess the prevalence of malocclusion and treatment need in children and adolescents with sickle cell disease (SCD).
  
  
  METHODS
  In this cross-sectional study, the sample size comprised 35 five-year-old children and 36 adolescents of both sexes, aged between 12 to 18 years, with SCD. Dental occlusion was assessed using two indexes: the Malocclusion Index (World Health Organization) and the Dental Aesthetic Index (DAI).
  
  
  RESULTS
  The prevalence of malocclusion in the preschool children was 62.9%. The main malocclusions observed in this age group were Class II (37.1%), increased overjet (28.6%), reduced overbite (28.6%), and open bite (17.1%). In the 12- to 18-year-old subjects, the prevalence of malocclusion was 100%, and the most prevalent types of malocclusion were maxillary overjet (63.9%) and maxillary misalignment (58.3%). It is noteworthy that the majority of adolescents (80.6%) had very severe or disabling malocclusions.
  
  
  CONCLUSIONS
  The results revealed a high prevalence of malocclusion in children and adolescents with SCD. According to DAI score, the majority of the sample presented with very severe malocclusion and a compulsory treatment need.
authors.affiliation: a  PhD Student, Pediatric Dentistry, Dental School, University of Pernambuco, Camaragibe, Pernambuco, Brazil.
authors.forename: Ana Cláudia
authors.initials: AC
authors.lastname: Alves e Luna
authors.forename: Fabiana
authors.initials: F
authors.lastname: Godoy
authors.forename: Valdenice Aparecida
authors.initials: VA
authors.lastname: de Menezes
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000755:Anemia, Sickle Cell / Q000453:epidemiology*; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004522:Educational Status; D016021:Epidemiologic Studies; D004955:Esthetics, Dental; D005260:Female; D006801:Humans; D007182:Income / Q000706:statistics & numerical data; D008297:Male; D008310:Malocclusion / Q000453:epidemiology*; D008311:Malocclusion, Angle Class I / Q000453:epidemiology; D008312:Malocclusion, Angle Class II / Q000453:epidemiology; D020380:Needs Assessment / Q000706:statistics & numerical data*; D024343:Open Bite / Q000453:epidemiology; D057887:Overbite / Q000453:epidemiology; D010290:Parents / Q000193:education; D015995:Prevalence; D012111:Residence Characteristics / Q000706:statistics & numerical data; D016388:Tooth Loss / Q000453:epidemiology