title: Probable initial pulmonary lymphangioleiomyomatosis and mediastinal lymphangioleiomyoma.
abstract: A 68 year old woman was submitted to a mediastinal lymphangioleiomyoma resection found in a follow-up study of lower left lung resection due to bronchiectasis complicated by chylothorax. This led to a revaluation of the pulmonary specimen that revealed, in addition to inflammatory bronchiectasis, small spindle cell nodules in the lung parenchyma, similar to minute pulmonary meningothelial-like nodules, but with smooth muscle actin immunohistochemical positivity. The possibility of initial pulmonary development of lymphangioleiomyomatosis is discussed.
authors.affiliation: Serviço de Anatomia Patológica, Centro Hospitalar Universitário de Coimbra, Hospitais da Universidade de Coimbra, Coimbra, Portugal. Electronic address: manuelpontes1@sapo.pt.
authors.forename: M
authors.initials: M
authors.lastname: Pontes
authors.affiliation: Serviço de Anatomia Patológica, Instituto Português de Oncologia FG, Coimbra, Portugal.
authors.forename: C
authors.initials: C
authors.lastname: Barbosa
authors.affiliation: Serviço de Radiologia, Hospital Infante D. Pedro, EPE, Aveiro, Portugal.
authors.forename: M L
authors.initials: ML
authors.lastname: Coelho
authors.affiliation: Serviço de Anatomia Patológica, Centro Hospitalar Universitário de Coimbra, Hospitais da Universidade de Coimbra, Coimbra, Portugal; Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal; Pólo das Ciências da Saúde - Unidade Central, Instituto de Anatomia Patológica, Coimbra, Portugal.
authors.forename: L
authors.initials: L
authors.lastname: Carvalho
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D018192:Lymphangioleiomyomatosis / Q000473:pathology*; D008203:Lymphangiomyoma / Q000473:pathology*; D008479:Mediastinal Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*
keywords: Linfangioleiomioma; Linfangioleiomiomatose; Lymphangioleiomyoma; Lymphangioleiomyomatosis; Mediastinal