title: Endoscopic endonasal transsphenoidal approach for sellar tumors beyond the sellar turcica.
abstract: CONCLUSIONS
  The endoscopic endonasal transsphenoidal approach can be a choice for sellar tumors beyond the sellar turcica, but it is necessary to make the choice carefully because of the severe surgical risks.
  
  
  OBJECTIVE
  To summarize our experience of removal of sellar tumors beyond the sellar turcica via the endoscopic endonasal transsphenoidal approach and to evaluate the surgical efficacy and complications.
  
  
  METHODS
  Between January 2007 and January 2012, 30 patients with sellar tumors beyond the sellar turcica underwent surgery using the endoscopic endonasal transsphenoidal approach.
  
  
  RESULTS
  Postoperative pathological examination demonstrated that pituitary adenoma occurred in 22 patients, craniopharyngioma in 5, and meningioma in 3. Total removal was achieved in 21 patients (70.0%) and subtotal removal was achieved in 8 patients (26.7%). After the surgery, cerebrospinal fluid leakage occurred in 3 patients, temporary diabetes insipidus occurred in 25 patients and persistent diabetes insipidus in 4 patients, intracranial infection occurred in 1 patient, frontal subdural effusion occurred in 1 patient, sinusitis occurred in 2 patients, epistaxis occurred in 3 patients, and 1 patient with a huge pituitary adenoma died of hypothalamic failure related to the operation.
authors.affiliation: Department of Otolaryngology-Head Neck Surgery, Third Xiangya Hospital of Central South University , Changsha, Hunan.
authors.forename: Yexun
authors.initials: Y
authors.lastname: Song
authors.forename: Heqing
authors.initials: H
authors.lastname: Li
authors.forename: Huowang
authors.initials: H
authors.lastname: Liu
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Zhang
authors.forename: Lian
authors.initials: L
authors.lastname: Guo
authors.forename: Guolin
authors.initials: G
authors.lastname: Tan
mesh_terms: D000236:Adenoma / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002559:Cerebrospinal Fluid Rhinorrhea / Q000209:etiology; D002648:Child; D003397:Craniopharyngioma / Q000601:surgery*; D003919:Diabetes Insipidus / Q000209:etiology; D004724:Endoscopy / Q000379:methods*; D004844:Epistaxis / Q000209:etiology; D005260:Female; D006801:Humans; D007027:Hypothalamic Diseases / Q000209:etiology; D008297:Male; D008577:Meningeal Neoplasms / Q000601:surgery*; D008579:Meningioma / Q000601:surgery*; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology; D012658:Sella Turcica / Q000601:surgery*; D013101:Sphenoid Sinus / Q000601:surgery*; D013353:Subdural Effusion / Q000209:etiology; D013530:Surgical Wound Infection / Q000209:etiology; D016896:Treatment Outcome; D055815:Young Adult