title: Bacteriophage mv4 site-specific recombination: the central role of the P2 mv4Int-binding site.
abstract: The contributions of the five (mv4)Int- and two (mv4)Xis arm-binding sites to the spatial intasome organization of bacteriophage mv4 were found not to be equivalent. The 8-bp overlap region was mapped to the left extremity of the core region and is directly flanked by the P2 Int arm-binding site. These results and the absence of characteristic Int core-binding sites suggest that the P2 site is the determinant for integrase positioning and recognition of the core region.
authors.affiliation: Université de Toulouse, Université Paul Sabatier, Laboratoire de Microbiologie et de Génétique Moléculaires, Toulouse, France.
authors.forename: Michèle
authors.initials: M
authors.lastname: Coddeville
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Spinella
authors.forename: Pauline
authors.initials: P
authors.lastname: Cassart
authors.forename: Guillaume
authors.initials: G
authors.lastname: Girault
authors.forename: Marie-Line
authors.initials: ML
authors.lastname: Daveran-Mingot
authors.forename: Pascal
authors.initials: P
authors.lastname: Le Bourgeois
authors.forename: Paul
authors.initials: P
authors.lastname: Ritzenthaler
mesh_terms: D001287:Attachment Sites, Microbiological; D001435:Bacteriophages / Q000737:chemistry / Q000201:enzymology* / Q000235:genetics* / Q000502:physiology; D001483:Base Sequence; D001665:Binding Sites; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D019426:Integrases / Q000235:genetics / Q000378:metabolism*; D048668:Lactobacillus delbrueckii / Q000821:virology*; D008969:Molecular Sequence Data; D011995:Recombination, Genetic; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism*; D016662:Virus Integration
chemical_list: D004279:DNA, Viral; D014764:Viral Proteins; D019426:Integrases