title: Carbohydrate recognition by rotaviruses.
abstract: Rotaviruses are a global health concern causing severe childhood diarrhea. Though the mechanisms mediating rotavirus cell entry require further characterisation, it is acknowledged that an essential and critical step in rotavirus infection is the virus cell attachment via initial recognition of cell surface carbohydrate-containing receptors. This review summarises the current knowledge about recognition of glycan receptors by rotaviruses.
authors.affiliation: Institute for Glycomics, Griffith University, Gold Coast campus, QLD, 4222, Australia, x.yu@griffith.edu.au.
authors.forename: Xing
authors.initials: X
authors.lastname: Yu
authors.forename: Helen
authors.initials: H
authors.lastname: Blanchard
mesh_terms: D000818:Animals; D018360:Crystallography, X-Ray; D003967:Diarrhea / Q000821:virology; D006801:Humans; D019158:N-Acetylneuraminic Acid / Q000378:metabolism; D009438:Neuraminic Acids / Q000378:metabolism; D016601:RNA-Binding Proteins / Q000235:genetics / Q000378:metabolism / Q000648:ultrastructure*; D011991:Receptors, Virus / Q000378:metabolism*; D012401:Rotavirus / Q000235:genetics*; D012400:Rotavirus Infections / Q000821:virology; D017361:Viral Nonstructural Proteins / Q000235:genetics / Q000378:metabolism / Q000648:ultrastructure*; D053585:Virus Attachment; D053586:Virus Internalization
chemical_list: D009438:Neuraminic Acids; D016601:RNA-Binding Proteins; D011991:Receptors, Virus; D017361:Viral Nonstructural Proteins; C032592:N-glycolylneuraminic acid; C079234:NS35 protein, rotavirus; D019158:N-Acetylneuraminic Acid