title: Necrotizing skin and soft tissue infections.
abstract: Necrotizing skin and soft tissue infections are severe bacterial infections resulting in rapid and life-threatening soft tissue destruction and necrosis along soft tissue planes.
authors.affiliation: Division of Trauma, Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital, Harvard Medical School, 165 Cambridge Street, Suite 810, Boston, MA 02114, USA. Electronic address: hkaafarani@partners.org.
authors.forename: Haytham M A
authors.initials: HM
authors.lastname: Kaafarani
authors.forename: David R
authors.initials: DR
authors.lastname: King
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003646:Debridement / Q000379:methods; D004632:Emergency Medical Services / Q000379:methods; D019115:Fasciitis, Necrotizing / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality / Q000601:surgery*; D018934:Fournier Gangrene / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000601:surgery; D005738:Gas Gangrene / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000601:surgery; D006801:Humans; D009336:Necrosis; D011379:Prognosis; D018805:Sepsis / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000601:surgery; D012867:Skin / Q000473:pathology*; D012874:Skin Diseases, Infectious / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality / Q000601:surgery*; D016038:Skin Transplantation / Q000379:methods; D018461:Soft Tissue Infections / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality / Q000601:surgery*; D015996:Survival Rate; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents
keywords: Fournier’s gangrene; Gas gangrene; Necrotizing fasciitis; Necrotizing skin and soft tissue infection (NSSTI); Wide local debridement