title: Can bariatric surgery be performed safely in patients with severe treatment-resistant asthma?
abstract: Obesity-associated severe asthma is a distinct phenotype characterised by resistance to standard asthma therapies. Bariatric surgery appears to be a viable alternative for those who have failed trials of traditional weight loss methods. However, anaesthetic and surgical risks are potential barriers. We describe three patients with treatment-resistant obesity-associated severe asthma who underwent bariatric surgery without complications due to the multidisciplinary perioperative planning and care involved in these complex cases. All three patients showed improvements in asthma control and reduction in maintenance medication use post-surgery.
authors.affiliation: Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore, joseph.toh@mohh.com.sg.
authors.forename: Joseph Jia Hong
authors.initials: JJ
authors.lastname: Toh
authors.forename: Shanker
authors.initials: S
authors.lastname: Pasupathy
authors.forename: Ruban A L
authors.initials: RA
authors.lastname: Poopalalingam
authors.forename: Mariko Siyue
authors.initials: MS
authors.lastname: Koh
mesh_terms: D000328:Adult; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage*; D001249:Asthma / Q000150:complications* / Q000188:drug therapy* / Q000503:physiopathology; D050110:Bariatric Surgery; D015992:Body Mass Index; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D012074:Remission Induction; D012720:Severity of Illness Index; D015431:Weight Loss
chemical_list: D018927:Anti-Asthmatic Agents