title: Abasic site-binding ligands conjugated with cyanine dyes for "off-on" fluorescence sensing of orphan nucleobases in DNA duplexes and DNA-RNA hybrids.
abstract: A series of abasic site-binding ligands conjugated with cyanine dyes have been developed for "off-on" fluorescence sensing of an orphan nucleobase in DNA duplexes and DNA-RNA hybrids.
authors.affiliation: Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan. teramae@m.tohoku.ac.jp.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Sato
authors.forename: Megumi
authors.initials: M
authors.lastname: Kudo
authors.forename: Yu
authors.initials: Y
authors.lastname: Toriyabe
authors.forename: Shota
authors.initials: S
authors.lastname: Kuchitsu
authors.forename: Chun-xia
authors.initials: CX
authors.lastname: Wang
authors.forename: Seiichi
authors.initials: S
authors.lastname: Nishizawa
authors.forename: Norio
authors.initials: N
authors.lastname: Teramae
mesh_terms: D052160:Benzothiazoles / Q000737:chemistry; D002232:Carbocyanines / Q000737:chemistry*; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D005456:Fluorescent Dyes / Q000737:chemistry*; D008024:Ligands; D009287:Naphthyridines / Q000737:chemistry; D009690:Nucleic Acid Conformation; D011804:Quinolines / Q000737:chemistry; D012313:RNA / Q000737:chemistry* / Q000378:metabolism; D013050:Spectrometry, Fluorescence
chemical_list: C528376:2-amino-5,6,7-trimethyl-1,8-naphthyridine; D052160:Benzothiazoles; D002232:Carbocyanines; D005456:Fluorescent Dyes; D008024:Ligands; D009287:Naphthyridines; D011804:Quinolines; C051000:thiazole orange; D012313:RNA; D004247:DNA