title: Histone 3 s10 phosphorylation: "caught in the R loop!".
abstract: In this issue of Molecular Cell, Castellano-Pozo et al. (2013) describe a connection between R loop structures and histone 3 S10 phosphorylation (H3S10P), a mark of chromatin compaction. Their results constitute a significant advance in our understanding of the role of R loops in genomic instability.
authors.affiliation: Sir William Dunn School of Pathology, South Parks Road, University of Oxford, Oxford OX1 3RE, UK.
authors.forename: Konstantina
authors.initials: K
authors.lastname: Skourti-Stathaki
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Proudfoot
mesh_terms: D000818:Animals; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D004277:DNA, Single-Stranded / Q000235:genetics*; D006657:Histones / Q000378:metabolism*; D006801:Humans; D011499:Protein Processing, Post-Translational; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*
chemical_list: D029742:Caenorhabditis elegans Proteins; D004277:DNA, Single-Stranded; D006657:Histones; D029701:Saccharomyces cerevisiae Proteins