title: Of fish and men: using zebrafish to fight human diseases.
abstract: Long restricted to the field of developmental biology, the use of the zebrafish (Danio rerio) has extended to the study of human pathogenesis. Fostered by the rapid adaptation of new technologies, the design and analysis of fish models of human diseases have contributed important findings that are now making their way from aquariums to clinics. Here we outline the clinical relevance of the zebrafish as a model organism.
authors.affiliation: Stem Cell Program and Division of Hematology/Oncology, Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA.
authors.forename: Julien
authors.initials: J
authors.lastname: Ablain
authors.forename: Leonard I
authors.initials: LI
authors.lastname: Zon
mesh_terms: D000818:Animals; D004194:Disease; D004195:Disease Models, Animal; D006801:Humans; D057170:Translational Research, Biomedical; D015027:Zebrafish / Q000502:physiology*