title: Adjuvant therapy for a 3.9-cm adenocarcinoma of the lung.
abstract: After routine staging tests, including a FDG-PET scan and MRI of the brain, a 59-year-old mother of four, never smoker, undergoes uncomplicated right lower lobectomy of the lung to remove a 3.9 cm adenocarcinoma with visceral pleural invasion (pIB,T2N0M0). Should she receive adjuvant chemotherapy? If so, what drug, dose, and schedule?
authors.affiliation: Massachusetts General Hospital Cancer Center.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Heist
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Azzoli
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000235:genetics / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D000077192:Adenocarcinoma of Lung; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000627:therapeutic use; D066246:ErbB Receptors / Q000235:genetics; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D008875:Middle Aged; D009154:Mutation; D012907:Smoking
chemical_list: C512478:EGFR protein, human; D066246:ErbB Receptors; D002945:Cisplatin