title: Two new ceramides from the fruit pulp of Acanthopanax senticosus (Rupr. et Maxim) Harms.
abstract: Two new ceramides, (3S,4S,5R)-3-octadecanoylamino-4-hydroxy-5-dodecane-2,3,4,5-tetrahydrofuran (1) and (3S,4S,5R)-3-[(2R)-2-hydroxyhexacosanoylamino]-4-hydroxy-5-[(4E)-dodecane-4-ene]-2,3,4,5-tetrahydrofuran (2), together with eight known compounds, eleutheroside A (3), eleutheroside B (4), eleutheroside E (5), 7-hydroxy-6-methoxy-coumarin (6), 6,7-dimethoxycoumarin (7), 5α,8α-epidioxyergosta-6,22-dien-3-ol (8), stigmasterol (9) and rutin (10), were isolated from the fruit pulp of Acanthopanax senticosus (Rupr. et Maxim) Harms. Their structures were elucidated by means of physicochemical properties and spectroscopic methods (1D, 2D NMR and MS).
authors.affiliation: a Department of Clinical Pharmacology , The First Affiliated Hospital of Soochow University , Suzhou , Jiangsu 215006 , P.R. China.
authors.forename: Zhaowei
authors.initials: Z
authors.lastname: Yan
authors.forename: Jinping
authors.initials: J
authors.lastname: Liu
authors.forename: Dan
authors.initials: D
authors.lastname: Lu
authors.forename: Rajeshwar
authors.initials: R
authors.lastname: Narlawar
authors.forename: Paul
authors.initials: P
authors.lastname: Groundwater
authors.forename: Pingya
authors.initials: P
authors.lastname: Li
mesh_terms: D002518:Ceramides / Q000737:chemistry / Q000302:isolation & purification*; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D028001:Eleutherococcus / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification; D019906:Nuclear Magnetic Resonance, Biomolecular; D012431:Rutin / Q000737:chemistry / Q000302:isolation & purification; D013237:Stereoisomerism; D013265:Stigmasterol / Q000737:chemistry / Q000302:isolation & purification
chemical_list: C000590959:(3S,4S,5R)-3-((2R)-2-hydroxyhexacosanoylamino)-4-hydroxy-5-((4E)-dodecane-4-ene)-2,3,4,5-tetrahydrofuran; C000590958:(3S,4S,5R)-3-octadecanoylamino-4-hydroxy-5-dodecane-2,3,4,5-tetrahydrofuran; D002518:Ceramides; D003374:Coumarins; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D017705:Lignans; D012431:Rutin; C421885:eleutheroside E; D013265:Stigmasterol; C018145:scoparone