title: Resolution of "salt and pepper" appearance of the skull with vitamin D therapy.
abstract: Chronic hypovitaminosis D leads to state of decreased mineralization and generalized osteomalacia. It also results in secondary hyperparathyroidism causing increased bone turn over and decreased bone mass, manifested radiologically as a "salt and pepper" appearance in skull, subperiosteal resorption, bone cysts and lytic lesions. In this case, a young male patient with hypovitaminosis D and secondary hyperparathyroidism, radiological features show resolution of "salt and pepper" appearance of the skull with vitamin D in 11 months and regression of other lytic lesions.
authors.affiliation: Department of Internal Medicine (Endocrinology), Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
authors.forename: Gursimran
authors.initials: G
authors.lastname: Kaur
authors.forename: Parminder
authors.initials: P
authors.lastname: Singh
authors.forename: Naveen
authors.initials: N
authors.lastname: Mittal
authors.forename: Mani Kant
authors.initials: MK
authors.lastname: Singla
keywords: Osteitis fibrosa cystica; salt and pepper appearance; secondary hyperparathyroidism; vitamin D deficiency