title: Minimal invasive surgery in treatment of liver metastases from colorectal carcinomas: case studies and survival rates.
abstract: BACKGROUND
  Liver represents the main organ subject to metastases from colorectal tumors. Resections of liver metastases from colorectal cancer have a well-considered therapeutic role underlined by survival of 5 years by approximately 50-60% of surgical cases as is deduced from an analysis of the most recent literature. The objective of surgery is to eradicate the metastases present and obtain a margin free from neoplastic impact of amplitude of approximately 1 cm with residual liver quantity at the end of the intervention that allows the patient to survive. Currently the dimensions and the number of colorectal liver metastases (CRLM) do not limit the hepatectomy. Purpose of this work is to evaluate the survival, according to our case studies of patients treated only with the wedge resection (atypical resection) approximately 1 cm from the margins of metastases.
  
  
  METHODS
  In "A. Rizzoli" Lacco Ameno Hospital (Ischia), from 2005 to 2010, 12 liver resections were performed for metastases from colorectal carcinoma with atypical resection. Synchronous surgical treatment with resection of the colorectal carcinoma and metastases was performed in 6 patients, 2 female and 4 male (Group 1). Surgical liver metastasectomy post-colectomy was performed on 6 patients, 3 female and 3 male (Group 2).
  
  
  RESULTS
  No patient was treated with chemotherapy. The mortality rate of intraoperative and perioperative infection was in both cases of 0%. Survival:11 patients treated surgically from 2005-2010 with synchronous surgery resection (Group 1) and liver metastasectomy (Group 2) are currently living. One 77-years-old patient died three years after surgery for BPCO.
  
  
  CONCLUSIONS
  This result was able to be obtained due to the wedge resection technique routinely used in our Hospital, associated with the indispensable use of intraoperatory ultrasound (IOUS). Significant differences between the synchronous and non-synchronous intervention emerged only regarding the number of days of hospital stay, higher in the first case.
authors.forename: Domenico
authors.initials: D
authors.lastname: Loffredo
authors.forename: Alberto
authors.initials: A
authors.lastname: Marvaso
authors.forename: Sandro
authors.initials: S
authors.lastname: Ceraso
authors.forename: Nicola
authors.initials: N
authors.lastname: Cinelli
authors.forename: Aldo
authors.initials: A
authors.lastname: Rocca
authors.forename: Mario
authors.initials: M
authors.lastname: Vitale
authors.forename: Michele
authors.initials: M
authors.lastname: Rossi
authors.forename: Eugenio
authors.initials: E
authors.lastname: Genovese
authors.forename: Bruno
authors.initials: B
authors.lastname: Amato
authors.forename: Mariapia
authors.initials: M
authors.lastname: Cinelli
mesh_terms: D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D012189:Retrospective Studies; D015996:Survival Rate