title: Molecular pathology techniques.
abstract: Molecular pathology techniques have matured considerably over the last decade. New technologies have provided increased sensitivity for improved diagnostic capacity. Furthermore, novel methodologies have matured to interrogate nucleic acid and protein signatures effectively to aid in elucidating the pathophysiology of disease in addition to diagnosis, prognosis, and therapeutic monitoring for patient management. Here general molecular techniques used in the molecular pathology laboratory as they are used for clinical applications are described.
authors.affiliation: Genome Dynamics International, Uniondale, NY 11556, USA. Electronic address: mark.bluth@gendyn.us.
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Bluth
authors.forename: Martin H
authors.initials: MH
authors.lastname: Bluth
mesh_terms: D006801:Humans; D025202:Molecular Diagnostic Techniques; D015336:Molecular Probe Techniques; D057089:Pathology, Molecular
keywords: FISH; Hybrid capture; Methodology; Molecular pathology; RFLP; RT-PCR; SNP