title: Diagnostic exome sequencing: a new paradigm in neurology.
abstract: Genomic tools have evolved with remarkable rapidity, but their clinical relevance and application have lagged behind. Now, consistent clinical applications have finally arrived and bring with them the promise of identifying the underlying causes of complex neurological disorders in a patient-specific manner.
authors.affiliation: Department of Neurology, Beaumont Hospital, Royal College of Surgeons, Dublin 9, Ireland. Electronic address: normandelanty@eircom.net.
authors.forename: Norman
authors.initials: N
authors.lastname: Delanty
authors.forename: David B
authors.initials: DB
authors.lastname: Goldstein
mesh_terms: D059472:Exome / Q000235:genetics*; D016678:Genome; D006801:Humans; D008967:Molecular Biology; D009422:Nervous System Diseases / Q000175:diagnosis / Q000235:genetics; D009446:Neurobiology / Q000379:methods* / Q000639:trends*; D017421:Sequence Analysis; D017422:Sequence Analysis, DNA