title: Synthesis and properties of a Cu(II) complexing pyrazole ligandoside in DNA.
abstract: The development of metal base pairs is of immense importance for the construction of DNA nanostructures. Here we report the synthesis of a biaryl pyrazole-phenol nucleoside that forms in DNA a stable self-pair upon complexation of a Cu(II) ion. A sequence with five consecutive pyrazole nucleotides allows the complexation of five Cu(II) ions in a row.
authors.affiliation: Department of Chemistry, Ludwig-Maximilians University, Butenandtstraße 5-13, 81377, Munich, Germany. thomas.carell@cup.uni-muenchen.de.
authors.forename: M
authors.initials: M
authors.lastname: Su
authors.forename: María
authors.initials: M
authors.lastname: Tomás-Gamasa
authors.forename: S
authors.initials: S
authors.lastname: Serdjukow
authors.forename: P
authors.initials: P
authors.lastname: Mayer
authors.forename: T
authors.initials: T
authors.lastname: Carell
mesh_terms: D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry*; D008968:Molecular Conformation; D009711:Nucleotides / Q000138:chemical synthesis / Q000737:chemistry*; D011720:Pyrazoles / Q000737:chemistry*; D044366:Transition Temperature
chemical_list: D056831:Coordination Complexes; D009711:Nucleotides; D011720:Pyrazoles; C031280:pyrazole; D003300:Copper; D004247:DNA