title: Bone scintigraphic patterns in patients of tumor induced osteomalacia.
abstract: Tumor induced osteomalacia (TIO) or oncogenic osteomalacia is a rare condition associated with small tumor that secretes one of the phosphaturic hormones, i.e., fibroblast growth factor 23, resulting in abnormal phosphate metabolism. Patients may present with non-specific symptoms leading to delay in the diagnosis. Extensive skeletal involvement is frequently seen due to delay in the diagnosis and treatment. The small sized tumor and unexpected location make the identification of tumor difficult even after diagnosis of osteogenic osteomalacia. The bone scan done for the skeletal involvement may show the presence of metabolic features and the scan findings are a sensitive indicator of metabolic bone disorders. We present the bone scan findings in three patients diagnosed to have TIO.
authors.affiliation: Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Ashwani
authors.initials: A
authors.lastname: Sood
authors.forename: Kanhaiyalal
authors.initials: K
authors.lastname: Agarwal
authors.forename: Jaya
authors.initials: J
authors.lastname: Shukla
authors.forename: Reema
authors.initials: R
authors.lastname: Goel
authors.forename: Varun
authors.initials: V
authors.lastname: Dhir
authors.forename: Anish
authors.initials: A
authors.lastname: Bhattacharya
authors.forename: Bhagwant
authors.initials: B
authors.lastname: Rai Mittal
keywords: Bone scan; fibroblast growth factor 23; hypophosphatemia; tumor induced osteomalacia