title: Awakened by a sleeping pill.
abstract: Characteristic changes in brain activity accompany the paradoxical increase in alertness observed in some patients with severe brain injury when they are treated with the sleeping pill zolpidem.
authors.affiliation: Oluwaseun Akeju is at the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, United States.
authors.forename: Oluwaseun
authors.initials: O
authors.lastname: Akeju
authors.forename: Emery N
authors.initials: EN
authors.lastname: Brown
mesh_terms: D001930:Brain Injuries / Q000503:physiopathology*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*; D000077334:Zolpidem
chemical_list: D006993:Hypnotics and Sedatives; D011725:Pyridines; D000077334:Zolpidem
keywords: Consciousness; GABA-A; anesthesia; arousal; central thalamus; striatum