title: Diabetes insipidus as a presenting manifestation of Rathke's cleft cyst.
abstract: Rathke's cleft cysts (RCC) are cystic sellar and suprasellar lesions derived from remnants of Rathke's pouch, lined by cuboidal or columnar epithelium. RCC are usually asymptomatic but can present with headache, visual impairment, panhypopituitarism and hypothalamic dysfunction. Diabetes Insipidus as a presenting symptom of RCC is reported, but rare. We present a case of a 48-year-old male presenting with polyuria and on investigations found to have central diabetes insipidus due to a sellar RCC. Patient underwent transsphenoidal surgery with complete excision with resolution of his symptoms. His polyuria resolved post-surgery without vasopressin replacement, which has never been reported.
authors.affiliation: Department of Endocrinology and Metabolism, IPGMER and SSKM Hospital, Kolkata, West Bengal, India.
authors.forename: Manoj
authors.initials: M
authors.lastname: Kumar
authors.forename: Deep
authors.initials: D
authors.lastname: Dutta
authors.forename: K S
authors.initials: KS
authors.lastname: Shivaprasad
authors.forename: Rajesh
authors.initials: R
authors.lastname: Jain
authors.forename: Ankita
authors.initials: A
authors.lastname: Sen
authors.forename: Dibakar
authors.initials: D
authors.lastname: Biswas
authors.forename: Madhumita
authors.initials: M
authors.lastname: Mukhopadhyay
authors.forename: Sujoy
authors.initials: S
authors.lastname: Ghosh
authors.forename: Satinath
authors.initials: S
authors.lastname: Mukhopadhyay
authors.forename: Subhankar
authors.initials: S
authors.lastname: Chowdhury
keywords: Diabetes insipidus; Rathke cyst; panhypopituitarism