title: Enzymes in clinical medicine: an overview.
abstract: Enzymes are biocatalysts and because of their remarkable properties, they are extensively used in medical diagnosis. Researches in the last two decades have concentrated more on enzymes such as creatine kinase-MB, alanine transaminase, aspartate transaminase, acid phosphatase, alkaline phosphatase etc. for clinical applications. Enzymes are the preferred markers in various disease states such as myocardial infarction, jaundice, pancreatitis, cancer, neurodegenerative disorders, etc. They provide insight into the disease process by diagnosis, prognosis and assessment of response therapy. Even though the literature on the use of enzymes in various disease conditions has accumulated, a comprehensive analysis is lacking and hence this review.
authors.affiliation: Department of Biotechnology, CSIR-Central Leather Research Institute, Adyar, Chennai 600 020, India.
authors.forename: Thiagarajan
authors.initials: T
authors.lastname: Hemalatha
authors.forename: Thiagamoorthy
authors.initials: T
authors.lastname: UmaMaheswari
authors.forename: Gunasekaran
authors.initials: G
authors.lastname: Krithiga
authors.forename: Palavesam
authors.initials: P
authors.lastname: Sankaranarayanan
authors.forename: Rengarajulu
authors.initials: R
authors.lastname: Puvanakrishnan
mesh_terms: D015415:Biomarkers / Q000032:analysis / Q000097:blood; D015374:Biosensing Techniques; D004796:Clinical Enzyme Tests / Q000379:methods*; D019937:Diagnostic Techniques and Procedures; D004798:Enzymes / Q000032:analysis / Q000097:blood; D006801:Humans
chemical_list: D015415:Biomarkers; D004798:Enzymes