title: The effect of the solute on the structure, selected mechanical properties, and biocompatibility of Ti-Zr system alloys for dental applications.
abstract: New titanium alloys have been developed with the aim of utilizing materials with better properties for application as biomaterials, and Ti-Zr system alloys are among the more promising of these. In this paper, the influence of zirconium concentrations on the structure, microstructure, and selected mechanical properties of Ti-Zr alloys is analyzed. After melting and swaging, the samples were characterized through chemical analysis, density measurements, X-ray diffraction, optical microscopy, Vickers microhardness, and elasticity modulus. In-vitro cytotoxicity tests were performed on cultured osteogenic cells. The results showed the formation essentially of the α' phase (with hcp structure) and microhardness values greater than cp-Ti. The elasticity modulus of the alloys was sensitive to the zirconium concentrations while remaining within the range of values of conventional titanium alloys. The alloys presented no cytotoxic effects on osteoblastic cells in the studied conditions.
authors.affiliation: UNESP - Univ. Estadual Paulista, Laboratório de Anelasticidade e Biomateriais, 17.033-360, Bauru, SP, Brazil.
authors.forename: D R N
authors.initials: DR
authors.lastname: Correa
authors.forename: F B
authors.initials: FB
authors.lastname: Vicente
authors.forename: T A G
authors.initials: TA
authors.lastname: Donato
authors.forename: V E
authors.initials: VE
authors.lastname: Arana-Chavez
authors.forename: M A R
authors.initials: MA
authors.lastname: Buzalaf
authors.forename: C R
authors.initials: CR
authors.lastname: Grandini
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology*; D016923:Cell Death / Q000187:drug effects; D002460:Cell Line; D049109:Cell Proliferation / Q000187:drug effects; D003722:Dental Alloys / Q000494:pharmacology*; D055119:Elastic Modulus / Q000187:drug effects; D006244:Hardness / Q000187:drug effects; D008422:Materials Testing; D051379:Mice; D014025:Titanium / Q000494:pharmacology*; D014961:X-Ray Diffraction; D015040:Zirconium / Q000032:analysis / Q000494:pharmacology*
chemical_list: D001672:Biocompatible Materials; D003722:Dental Alloys; D015040:Zirconium; D014025:Titanium
keywords: Biomaterials; Mechanical properties; Microstructure; Ti alloys