title: Antifungal activity of some substituted pyrimidines.
abstract: Several 6-chloro-5-nitropyrimidines were synthesized, and their antifungal activity was tested. Some derivatives were equipotent or superior to amphotericin B in vitro but their relatively high toxicity in mice and their chemical instability discourage further evaluation.
authors.affiliation: Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, Mississippi, 38677.
authors.forename: J D
authors.initials: JD
authors.lastname: McChesney
authors.forename: M
authors.initials: M
authors.lastname: Gonzalez-Sierra