title: High resolution and high definition anorectal manometry and pressure topography: diagnostic advance or a new kid on the block?
abstract: The recent development of closely spaced circumferential solid state transducers has paved the way for novel technology that includes high resolution anorectal manometry and topography (HRAM) and 3-D high definition anorectal manometry (HDAM). These techniques are increasingly being used for the assessment of anorectal neuromuscular function. However, whether they constitute a diagnostic advantage or a mere refinement of an old technology is unknown. Unlike the traditional manometry that utilized 3 or 6 unidirectional sensors, the closely spaced circumferential arrangement facilitates superior spatiotemporal mapping of pressures at rest and during various dynamic maneuvers. HDAM can provide knowledge of the three muscles that govern the anal continence namely, the puborectalis, and the internal and external anal sphincters, and can show how they mediate the rectoanal inhibitory reflex and sensorimotor responses and the spatiotemporal orientation of these muscles. Also, anal sphincter defects can be mapped and readily detected using 3-D technology. Similarly, HRAM has facilitated confirmation and development of phenotypes of dyssynergic defecation. Recently, normative data have also been reported with HRAM and HDAM, together with the influence of age, gender, and test instructions. The greater yield of anatomical and functional information may supersede the limitations of costs, fragility, and shorter life-span associated with these new techniques. Thus, HDAM and HRAM are not just new gadgets but constitute a significant and novel diagnostic advance. However, more prospective studies are needed to better define anorectal disorders with these techniques and to confirm their superiority.
authors.affiliation: Department of Medicine, Section of Gastroenterology & Hepatology, Georgia Regents University, 1120 15th Street, Augusta, GA, 30912, USA.
authors.forename: Yeong Yeh
authors.initials: YY
authors.lastname: Lee
authors.forename: Askin
authors.initials: A
authors.lastname: Erdogan
authors.forename: Satish S C
authors.initials: SS
authors.lastname: Rao
mesh_terms: D001003:Anal Canal / Q000502:physiology*; D003672:Defecation / Q000502:physiology; D004867:Equipment Design; D006801:Humans; D008365:Manometry / Q000295:instrumentation / Q000379:methods*; D011312:Pressure; D012002:Rectal Diseases / Q000175:diagnosis*; D012007:Rectum / Q000502:physiology*; D012016:Reference Values