title: Origin of life: Cold-hearted RNA heats up life.
abstract: An RNA replicase ribozyme has long been sought by chemists interested in the origin of life. Now, a selection strategy employing a low-temperature water–ice mixture as the medium has led to discovery of a ribozyme that can catalyse polymerization of an RNA chain greater than its own length.
authors.affiliation: Department of Chemistry at Portland State University, PO Box 751, Portland, Oregon 97207, USA.
authors.forename: Niles
authors.initials: N
authors.lastname: Lehman
mesh_terms: D019143:Evolution, Molecular; D012313:RNA / Q000737:chemistry* / Q000235:genetics*; D016337:RNA, Catalytic / Q000737:chemistry* / Q000235:genetics*; D012324:RNA-Dependent RNA Polymerase / Q000737:chemistry* / Q000235:genetics*
chemical_list: D016337:RNA, Catalytic; D012313:RNA; D012324:RNA-Dependent RNA Polymerase