title: Improved voluntary cough immediately following office-based vocal fold medialization injections.
abstract: OBJECTIVE
  This study examined changes in voluntary cough airflow measures immediately following in-office injection of Radiesse in patients diagnosed with glottic insufficiency. Due to significant comorbidities, these patients were poor candidates for medialization under general anesthesia. Each patient presented with dysphonia and dysphagia and ineffective voluntary cough, resulting in a poor clearing of secretions and a presence of ingested fluids on examination.
  
  
  METHODS
  Prospective cohort and case series study.
  
  
  METHODS
  Three patients with a diagnosis of glottic insufficiency were included for study based on flexible endoscopy and laryngostroboscopic examination. Voluntary cough airflow measures were obtained approximately 30 minutes before and after the Radiesse injections. The airflow measures were: compression phase duration (CPD), expiratory rise time (EPRT), expiratory phase peak airflow (EPPF), and cough volume acceleration (CVA).
  
  
  RESULTS
  Injection of Radiesse was found to improve voluntary cough airflow measures.
  
  
  CONCLUSIONS
  The immediate increase in the objective airflow measures obtained from voluntary cough production after Radiesse injections can be used to document airway protection improvements. Cough airflow is a straightforward measure to obtain and is considered an objective measure of cough function.
  
  
  METHODS
  4.
authors.affiliation: Department of Communication Sciences and Disorders, University of Central Florida, Orlando; The Ear Nose and Throat Surgical Associates, Orlando.
authors.forename: Bari H
authors.initials: BH
authors.lastname: Ruddy
authors.forename: Teresa E
authors.initials: TE
authors.lastname: Pitts
authors.forename: Jeff
authors.initials: J
authors.lastname: Lehman
authors.forename: Brian
authors.initials: B
authors.lastname: Spector
authors.forename: Vicki
authors.initials: V
authors.lastname: Lewis
authors.forename: Christine M
authors.initials: CM
authors.lastname: Sapienza
mesh_terms: D000328:Adult; D000368:Aged; D003371:Cough / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005931:Glottis; D006801:Humans; D007267:Injections; D058753:Laryngoplasty / Q000379:methods*; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D014827:Vocal Cords / Q000503:physiopathology* / Q000601:surgery; D014833:Voice Quality
keywords: Voice; cough; medialization; paralysis