title: Assessment of the relationship between non-alcoholic fatty liver disease and CAD using MSCT.
abstract: BACKGROUND
  Some risk factors for atherosclerosis are followed by non-alcoholic fatty liver disease (NAFLD). We wanted to use Multislice computed tomography (MSCT) as technique for searching relationship between NAFLD and coronary artery disease (CAD).
  
  
  OBJECTIVE
  The relationship between NAFLD and CAD was investigated using MSCT.
  
  
  METHODS
  A total of 372 individuals with or without cardiac symptoms who had undergone MSCT angiography were included in the study. The patients were divided into two groups according to the presence of NAFLD. Coronary artery segments were visually evaluated via MSCT angiography. Based on the coronary artery stenosis degree, those with no or minimal plaques were considered normal, whereas those who had stenosis of less than 50% and at least one plaque were considered to have non-obstructive coronary artery disease (non-obsCAD). The patients who had at least one plaque and coronary artery stenosis of 50% or more were considered to have obstructive coronary artery disease (obsCAD). NAFLD was determined according to the MSCT protocol, using the liver density.
  
  
  RESULTS
  According to the liver density, the number of patients with non-alcoholic fatty liver disease (group 1) was 204 (149 males, 54.8%) and with normal liver (group 2) was 168 (95 males, 45.2%). There were 50 (24.5%) non-obsCAD and 57 (27.9%) obsCAD cases in Group 1, and 39 (23.2%) non-obsCAD and 23 (13.7%) obsCAD cases in Group 2.
  
  
  CONCLUSIONS
  The present study using MSCT demonstrated that the frequency of coronary artery disease in patients with NAFDL was significantly higher than that of patients without NAFDL.
authors.affiliation: Mevlana University, Faculdade de Medicina, Departamento de Radiologia, Konya, Turquia.
authors.forename: Duran
authors.initials: D
authors.lastname: Efe
authors.affiliation: Mevlana University, Faculdade de Medicina, Departamento de Cirurgia Cardiovascular, Konya, Turquia.
authors.forename: Fatih
authors.initials: F
authors.lastname: Aygün
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D016009:Chi-Square Distribution; D017023:Coronary Angiography / Q000379:methods*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000209:etiology; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000473:pathology; D005234:Fatty Liver / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography / Q000379:methods*; D065626:Non-alcoholic Fatty Liver Disease; D012307:Risk Factors; D012737:Sex Factors; D055815:Young Adult