title: Multidetector computed tomographic imaging in chronic obstructive pulmonary disease: emphysema and airways assessment.
abstract: Chronic obstructive pulmonary disease (COPD) is a complex syndrome encompassing potentially overlapping diseases such as pulmonary emphysema, chronic bronchitis, and small airways disease. The management of COPD relies on distribution and severity of those processes, which clinically can manifest similarly. Relative contribution and severity of each of those pathologic changes can be assessed using qualitative and quantitative analysis of computed tomographic imaging data. Studies are under way to establish potential links among the imaging, clinical, and genetic manifestations of COPD.
authors.affiliation: Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue-Shapiro 4, Boston, MA 02215, USA. Electronic address: dlitmano@bidmc.harvard.edu.
authors.forename: Diana E
authors.initials: DE
authors.lastname: Litmanovich
authors.forename: Kirsten
authors.initials: K
authors.lastname: Hartwick
authors.forename: Mario
authors.initials: M
authors.lastname: Silva
authors.forename: Alexander A
authors.initials: AA
authors.lastname: Bankier
mesh_terms: D000402:Airway Obstruction / Q000000981:diagnostic imaging / Q000503:physiopathology; D003720:Densitometry; D006801:Humans; D061330:Multidetector Computed Tomography; D029424:Pulmonary Disease, Chronic Obstructive / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011656:Pulmonary Emphysema / Q000000981:diagnostic imaging* / Q000503:physiopathology
keywords: Airway imaging; COPD; CT; Emphysema; Phenotyping