title: [The impact of in-hospital pneumonia on the risk of in-hospital and long-term mortality in patients with acute ischemic stroke].
abstract: OBJECTIVE
  To observe the short-term and long-term impacts of in-hospital pneumonia on outcomes of patients hospitalized with acute ischemic stroke.
  
  
  METHODS
  All consecutive patients older than 18 years with acute ischemic stroke were prospectively recruited to this study, including 132 clinical centers in 32 provinces and 4 municipalities (including Hong Kong region) in China from September 2007 to August 2008. Case report form was designed. Data of pneumonia and survival outcomes at baseline; discharge; 3, 6 and 12 months after admission were recorded. Multivariable logistic regression was used for statistical correlation analysis.
  
  
  RESULTS
  A total of 1373 (11.88%) patients from 11 560 acute ischemic stroke patients were notified with in-hospital pneumonia. The case fatality rate was 14.4% (1664 patients) within 12 months after stroke onset. The fatality rate in patients with pneumonia was higher than that of patients without pneumonia.In-hospital pneumonia was an independent risk factor for death at discharge (adjusted OR = 5.916; 95%CI 4.470-7.831), at 3 months (adjusted OR = 3.641; 95%CI 3.035-4.367), 6 months (adjusted OR = 3.445; 95%CI 2.905-4.086), and 12 months (adjusted OR = 3.543; 95%CI 3.016-4.161) after onset.
  
  
  CONCLUSIONS
  In-hospital pneumonia is an adverse factor for the short-term and long-term survival of acute ischemic patients in China.
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Peng-lian
authors.initials: PL
authors.lastname: Wang
authors.forename: Xing-quan
authors.initials: XQ
authors.lastname: Zhao
authors.forename: Yi-long
authors.initials: YL
authors.lastname: Wang
authors.forename: Zhong-hua
authors.initials: ZH
authors.lastname: Yang
authors.forename: An-xin
authors.initials: AX
authors.lastname: Wang
authors.forename: Yong-jun
authors.initials: YJ
authors.lastname: Wang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000150:complications* / Q000175:diagnosis / Q000401:mortality; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000175:diagnosis* / Q000209:etiology*; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D020521:Stroke / Q000150:complications* / Q000175:diagnosis / Q000401:mortality