title: Microscopic colitis.
abstract: Microscopic colitis is a frequent cause of chronic watery diarrhea, especially in older persons. Common associated symptoms include abdominal pain, arthralgias, and weight loss. The incidence of microscopic colitis had been increasing, although more recent studies have shown a stabilization of incidence rates. The diagnosis is based on characteristic histologic findings in a patient with diarrhea. Microscopic colitis can occur at any age, including in children, but it is primarily seen in the elderly. Several treatment options exist to treat the symptoms of microscopic colitis, although only budesonide has been well studied in randomized clinical trials.
authors.affiliation: Division of Gastroenterology and Hepatology, Inflammatory Bowel Disease Clinic, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. Electronic address: Pardi.darrell@mayo.edu.
authors.forename: Darrell S
authors.initials: DS
authors.lastname: Pardi
mesh_terms: D000367:Age Factors; D000368:Aged; D000930:Antidiarrheals / Q000145:classification / Q000627:therapeutic use; D001706:Biopsy; D002908:Chronic Disease; D046729:Colitis, Collagenous / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology; D046730:Colitis, Lymphocytic / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology; D003106:Colon / Q000473:pathology*; D003113:Colonoscopy / Q000379:methods; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000175:diagnosis / Q000209:etiology; D013505:Digestive System Surgical Procedures; D006801:Humans; D007166:Immunosuppressive Agents / Q000145:classification / Q000627:therapeutic use; D015994:Incidence; D043183:Irritable Bowel Syndrome / Q000175:diagnosis*; D017063:Outcome Assessment, Health Care
chemical_list: D000930:Antidiarrheals; D007166:Immunosuppressive Agents
keywords: Collagenous colitis; Lymphocytic colitis; Microscopic colitis