title: The analgesic activity of neo-kyotorphin: a newly identified pentapeptide from bovine brain.
abstract: Analgesic effects of a novel pentapeptide from bovine brain, termed neo-kyotorphin (Thr-Ser-Lys-Tyr-Arg), were determined in mice after intracisternal injection. Neo-kyotorphin showed a dose-dependent analgesia with an ED50 value of 195 nmol/ mouse. This effect was not blocked by naloxone pretreatment.
authors.affiliation: Dept. of Pharmacology, Kagawa Medical School, Mikicho, Kagawa, 761-07, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Fukui
authors.forename: H
authors.initials: H
authors.lastname: Amano
authors.forename: Y
authors.initials: Y
authors.lastname: Kiso
authors.forename: K
authors.initials: K
authors.lastname: Kitagawa
authors.forename: H
authors.initials: H
authors.lastname: Takagi