title: A new benzopyran derivative from Pseuduvaria indochinensis Merr.
abstract: From the twigs and leaves of Pseuduvaria indochinensis Merr., a new benzopyran derivative, pseudindochin (1), was isolated together with three known compounds, oligandrol (2), (6E,10E)-isopolycerasoidol (3) and polycerasoidol (4). The structure of compound 1 was elucidated on the basis of extensive spectroscopic data interpretation, including 1D, 2D NMR, HR-ESI-MS, UV and IR. Moreover, compounds 1-4 were evaluated in vitro for their cytotoxic activities against HL-60 and SMMC-7721 cell lines, but these compounds were essentially non-cytotoxic (IC50>30 μg/mL).
authors.affiliation: a State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000 , P.R. China.
authors.forename: Cai-Gui
authors.initials: CG
authors.lastname: Zhao
authors.forename: Ming-Jun
authors.initials: MJ
authors.lastname: Yao
authors.forename: Jin-Wei
authors.initials: JW
authors.lastname: Yang
authors.forename: Ya-Lin
authors.initials: YL
authors.lastname: Chai
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Sun
authors.forename: Cheng-Shan
authors.initials: CS
authors.lastname: Yuan
mesh_terms: D029061:Annonaceae / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001578:Benzopyrans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018922:HL-60 Cells; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D001578:Benzopyrans; D004365:Drugs, Chinese Herbal; C000591031:pseudindochin