title: Erosive pustular dermatosis: new description of a possible cause of the non-healing burn wound.
abstract: BACKGROUND
  Erosive pustular dermatosis (EPD) is a cutaneous condition, characterised by sterile pustular lesions, erosions and crusting. Extensive or infected disease may result in scarring. EPD has never been reported following burn. The aim of this study was to describe the presentation and management of EPD complicating burns wounds.
  
  
  METHODS
  A consecutive series of EPD cases secondary to burn.
  
  
  RESULTS
  Six cases were identified. In each case, erosive lesions and crusts were located at the site of burn or at the site of split skin grafting after tangential burn excision. All cases presented as failure to heal or repeated wound breakdown, despite standard burn wound management. Pain was a significant feature in all cases. Microbiological cultures demonstrated either benign colonising bacteria or no pathogens. Time to EPD diagnosis by the interdisciplinary team was 126 ± 27 days (mean ± SEM). Topical therapy with short course, potent corticosteroids resulted in clinical remission in 15 ± 2 days (mean ± SEM) without clinical relapses after 15 ± 4 months (mean ± SEM).
  
  
  CONCLUSIONS
  EPD may occur following burns. EPD should be considered in the differential diagnosis of a non-healing burn wound and resolves readily with topical potent corticosteroid therapy.
authors.affiliation: Department of Plastic, Reconstructive and Burns Surgery, City Campus, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom. Electronic address: sammyalbenna@doctors.org.uk.
authors.forename: Sammy
authors.initials: S
authors.lastname: Al-Benna
authors.affiliation: Department of Plastic, Reconstructive and Burns Surgery, City Campus, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.
authors.forename: Kirsty
authors.initials: K
authors.lastname: Johnson
authors.affiliation: Department of Dermatology, Queen's Campus, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.
authors.forename: William
authors.initials: W
authors.lastname: Perkins
authors.affiliation: Department of Plastic, Reconstructive and Burns Surgery, City Campus, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.
authors.forename: Ciaran
authors.initials: C
authors.lastname: O'Boyle
mesh_terms: D000279:Administration, Cutaneous; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D002056:Burns / Q000150:complications / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D012872:Skin Diseases, Vesiculobullous / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D016038:Skin Transplantation; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D000305:Adrenal Cortex Hormones
keywords: Burn; Erosive pustular dermatosis; Reconstructive surgical procedures; Skin transplantation