title: Comparison of late HIV diagnosis as a marker of care for Aboriginal versus non-Aboriginal people living with HIV in Ontario.
abstract: BACKGROUND
  Studies have found that Aboriginal people living with HIV/AIDS (APHAs) are more likely than non-APHAs to receive suboptimal HIV care, yet achieve similar clinical outcomes with proper care.
  
  
  OBJECTIVE
  To compare the proportions of individuals diagnosed late with HIV between APHAs and non-APHAs within the Ontario HIV Treatment Network Cohort Study (OCS).
  
  
  METHODS
  The analysis included OCS participants who completed the baseline visit by November 2009. Two definitions of the outcome of late HIV diagnosis were used: the proportion of participants with an AIDS-defining illness (ADI) before or within three months of HIV diagnosis; and the proportion of participants with a CD4(+) count <200 cells/mL at diagnosis. Logistic regression analysis was used to assess the association between Aboriginal ethnicity and late HIV diagnosis.
  
  
  RESULTS
  APHAs were more likely to be female and have lower income, education and employment. No statistically significant differences were noted in the proportions receiving a late HIV diagnosis defined by ADI (Aboriginal 5.2% versus non-Aboriginal 6.3%; P=0.40). Multivariate logistic regression analysis revealed a significant association between Aboriginal ethnicity and late HIV diagnosis defined by CD4(+) count after adjusting for age and HIV risk factor (OR 1.55; P=0.04).
  
  
  CONCLUSIONS
  APHAs were more likely to have a CD4(+) count <200 cells/mL at diagnosis but had similar clinical outcomes from late diagnosis when defined by ADI. However, differences may be underestimated due to recruitment limitations and selection bias.
  
  
  CONCLUSIONS
  Additional work is needed to address the socioeconomic and health care needs of APHAs.
authors.affiliation: Faculty of Medicine, University of Toronto, Toronto;
authors.forename: Denise
authors.initials: D
authors.lastname: Jaworsky
authors.forename: Laverne
authors.initials: L
authors.lastname: Monette
authors.forename: Janet
authors.initials: J
authors.lastname: Raboud
authors.forename: Doe
authors.initials: D
authors.lastname: O'Brien-Teengs
authors.forename: Christina
authors.initials: C
authors.lastname: Diong
authors.forename: Sandra
authors.initials: S
authors.lastname: Blitz
authors.forename: Sean B
authors.initials: SB
authors.lastname: Rourke
authors.forename: Mona R
authors.initials: MR
authors.lastname: Loutfy
keywords: Aboriginal peoples; Access to care; Cohort study; HIV; HIV diagnosis; Quality of care