title: The use of carbon nanotubes to reinforce 45S5 bioglass-based scaffolds for tissue engineering applications.
abstract: Bioglass has been used for bone-filling material in bone tissue engineering, but its lean mechanical strength limits its applications in load-bearing positions. Carbon nanotubes (CNTs), with their high aspect ratio and excellent mechanical properties, have the potential to strengthen and toughen bioactive glass material without offsetting its bioactivity. Therefore, in this research, multiwall carbon nanotube (MWCNT)/45S5 Bioglass composite scaffolds have been successfully prepared by means of freeze casting process. 45S5 Bioglass was synthesized by the sol-gel processing method. The obtained material was characterized with X-ray powder diffraction (XRD). The mechanical properties of the scaffolds, such as compression strength and elastic modulus, were measured. Finally, compared with the scaffolds prepared by 100% 45S5 Bioglass powders, the addition of 0.25 wt.% MWCNTs increases the compressive strength and elastic modulus of 45S5 Bioglass scaffolds from 2.08 to 4.56 MPa (a 119% increase) and 111.50 to 266.59 MPa (a 139% increase), respectively.
authors.affiliation: Biomaterial Group, Faculty of Biomedical Engineering (Center of Excellence), Amirkabir University of Technology, P.O. Box 15875-4413, Tehran, Iran.
authors.forename: R
authors.initials: R
authors.lastname: Touri
authors.forename: F
authors.initials: F
authors.lastname: Moztarzadeh
authors.forename: Z
authors.initials: Z
authors.lastname: Sadeghian
authors.forename: D
authors.initials: D
authors.lastname: Bizari
authors.forename: M
authors.initials: M
authors.lastname: Tahriri
authors.forename: M
authors.initials: M
authors.lastname: Mozafari
mesh_terms: D001672:Biocompatible Materials; D001842:Bone and Bones; D002516:Ceramics / Q000737:chemistry* / Q000627:therapeutic use; D005898:Glass / Q000737:chemistry*; D006801:Humans; D008855:Microscopy, Electron, Scanning; D037742:Nanotubes, Carbon / Q000737:chemistry*; D044367:Phase Transition; D023822:Tissue Engineering; D054457:Tissue Scaffolds / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D037742:Nanotubes, Carbon; C425330:bioactive glass 45S5