title: DeNovoGUI: an open source graphical user interface for de novo sequencing of tandem mass spectra.
abstract: De novo sequencing is a popular technique in proteomics for identifying peptides from tandem mass spectra without having to rely on a protein sequence database. Despite the strong potential of de novo sequencing algorithms, their adoption threshold remains quite high. We here present a user-friendly and lightweight graphical user interface called DeNovoGUI for running parallelized versions of the freely available de novo sequencing software PepNovo+, greatly simplifying the use of de novo sequencing in proteomics. Our platform-independent software is freely available under the permissible Apache2 open source license. Source code, binaries, and additional documentation are available at http://denovogui.googlecode.com .
authors.affiliation: Max Planck Institute for Dynamics of Complex Technical Systems , Sandtorstraße 1, 39106 Magdeburg, Germany.
authors.forename: Thilo
authors.initials: T
authors.lastname: Muth
authors.forename: Lisa
authors.initials: L
authors.lastname: Weilnböck
authors.forename: Erdmann
authors.initials: E
authors.lastname: Rapp
authors.forename: Christian G
authors.initials: CG
authors.lastname: Huber
authors.forename: Lennart
authors.initials: L
authors.lastname: Martens
authors.forename: Marc
authors.initials: M
authors.lastname: Vaudel
authors.forename: Harald
authors.initials: H
authors.lastname: Barsnes
mesh_terms: D003196:Computer Graphics; D020539:Sequence Analysis, Protein; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014584:User-Computer Interface