title: Phosphine-catalyzed domino reaction: a novel sequential [2+3] and [3+2] annulation reaction of γ-substituent allenoates to construct bicyclic[3, 3, 0]octene derivatives.
abstract: We have successfully developed a novel and efficient phosphine-catalyzed sequential [2+3] and [3+2] annulation reaction of γ-substituent allenoates to construct bicyclic[3, 3, 0]octene derivatives. The protocol uses readily available γ-substituent allenoates as the starting materials, inexpensive PBu3 as the catalyst, and the corresponding products were obtained in good to excellent yields under mild conditions.
authors.affiliation: State Key Laboratory and Institute of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin),, Nankai University, Tianjin 300071, P. R. China. hyou@nankai.edu.cn.
authors.forename: Erqing
authors.initials: E
authors.lastname: Li
authors.forename: You
authors.initials: Y
authors.lastname: Huang
mesh_terms: D001643:Bridged Bicyclo Compounds / Q000737:chemistry; D002384:Catalysis; D061565:Cycloaddition Reaction; D009795:Octanes / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*
chemical_list: D001643:Bridged Bicyclo Compounds; D009795:Octanes; D010720:Phosphines; C044646:phosphine