title: Anti-inflammatory Effect of Bumblebee Alcohol Extracts in CFA-Induced Rat Edema.
abstract: In this study, we prepared alcohol extracts of the larva, pupa, queen, and cocoon (clony) of B. ignitus, B. terrestris, and B. h. sapporoensis, and tested the anti-inflammatory activity of the extracts by using a rat model of adjuvant-induced edema. The extracts derived from the queen of B. ignitus, the queen of B. terrestris, and the cocoon of B. ignitus decreased hind paw edema after 1 day of i.p. administration. These extracts also induced vasorelaxation and NO production in calf pulmonary artery endothelial cells. These results suggest that bumblebee alcohol extracts has anti-inflammatory and vasorelaxant properties.
authors.affiliation: Department of Agricultural Biology, National Academy of Agricultural Science, RDA, Suwon, Korea.
authors.forename: Mi Young
authors.initials: MY
authors.lastname: Ahn
authors.forename: Jea Woong
authors.initials: JW
authors.lastname: Han
authors.forename: Hyung Joo
authors.initials: HJ
authors.lastname: Yoon
authors.forename: Jae Sam
authors.initials: JS
authors.lastname: Hwang
authors.forename: Yun Eun
authors.initials: YE
authors.lastname: Young
keywords: Bumblebee alcohol extract; Edema