title: Three new diphenylpropanes from Celastrus hindsii.
abstract: Three new diphenylpropanes, Hindsiipropane A-C (1-3), together with one known arylpropyl quinone Griffithane D (4), were isolated from Celastrus hindsii. Their structures were established by 1D and 2D nuclear magnetic resonance spectroscopic analysis, and mass spectroscopy. Compound 4 was firstly obtained in this genus. All the isolated compounds were evaluated in vitro for cytotoxicity against four human tumor cell lines (A549, HCT116, MDA-MB-231, BEL7404) by the MTT assay.
authors.affiliation: School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China.
authors.forename: Xian Qing
authors.initials: XQ
authors.lastname: Hu
authors.forename: Wei
authors.initials: W
authors.lastname: Han
authors.forename: Zhu Zhen
authors.initials: ZZ
authors.lastname: Han
authors.forename: Qing Xin
authors.initials: QX
authors.lastname: Liu
authors.forename: Xi Ke
authors.initials: XK
authors.lastname: Xu
authors.forename: Peng
authors.initials: P
authors.lastname: Fu
authors.forename: Hui Liang
authors.initials: HL
authors.lastname: Li
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000302:isolation & purification* / Q000494:pharmacology; D031247:Celastrus / Q000737:chemistry*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D001713:Biphenyl Compounds