title: Electronic tuning of nitric oxide release from manganese nitrosyl complexes by visible light irradiation: enhancement of nitric oxide release efficiency by the nitro-substituted quinoline ligand.
abstract: Manganese nitrosyl {MnNO}(6) complexes of general formula [Mn(dpaq(R))(NO)]ClO4 (1R), where dpaq(R) denotes a series of pentadentate monoamido ligands, 2-[N,N-bis(pyridin-2-ylmethyl)]-amino-N'-quinolin-8-yl-acetamido with R = OMe, H, Cl and NO2 at the 5-position of the quinoline moiety, were prepared. The derivatives 1R were characterized by (1)H NMR, IR and UV-vis spectrometry as well as by single-crystal X-ray crystallography. The N-O bond and the amido C=O bond stretching frequencies, as well as the redox potentials of 1R derivatives, substantially varied depending on the nature of the substituent group R on the quinoline ring, indicating that the π back-bonding from Mn to NO groups becomes weak as the substituent group R becomes more electron withdrawing. The nitro-substituted derivative 1NO2 is unique among the series; the tail of its absorption bands extends to the NIR region (up to 700 nm), and the apparent NO releasing rate from 1NO2 by light irradiation at 650 nm was ca. 4-fold higher than the other derivatives.
authors.affiliation: Department of Molecular Chemistry and Biochemistry, Faculty of Science and Engineering, Doshisha University, 1-3 Tatara Miyakodani, Kyotanabe, Kyoto 610-0321, Japan. yhitomi@doshisha.ac.jp.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Hitomi
authors.forename: Yuji
authors.initials: Y
authors.lastname: Iwamoto
authors.forename: Masahito
authors.initials: M
authors.lastname: Kodera
mesh_terms: D056831:Coordination Complexes / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004583:Electrons; D008024:Ligands; D008027:Light; D009682:Magnetic Resonance Spectroscopy; D008345:Manganese / Q000737:chemistry*; D015394:Molecular Structure; D009569:Nitric Oxide / Q000737:chemistry*; D009589:Nitrogen Oxides / Q000737:chemistry*; D011804:Quinolines / Q000737:chemistry*
chemical_list: D056831:Coordination Complexes; D008024:Ligands; D009589:Nitrogen Oxides; D011804:Quinolines; D009569:Nitric Oxide; D008345:Manganese; C037219:quinoline; C087991:nitrosyl chloride