title: Mild increases in serum FSH in late follicular phase increases the risk of the luteinized unruptured follicle: case report.
abstract: OBJECTIVE
  To find a case that will support the concept that mild elevation of serum follicle stimulating hormone (FSH) levels in late follicular phase may interfere with the release of the oocyte from the follicle.
  
  
  METHODS
  Oocyte release was determined in a woman in a complete natural cycle vs cycles where a boost of very low dose FSH was given, human chorionic gonadotropin (hCG) 10,000 units or leuprolide acetate 1 mg every 12 hours x two doses was given in FSH stimulated cycles.
  
  
  RESULTS
  Oocyte release occurred in all natural cycles vs none of the mildly stimulated cycles.
  
  
  CONCLUSIONS
  Mild changes in the FSH level in the late luteal phase may affect the production of certain FSH dependent factors needed to release the oocyte.
authors.affiliation: Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com
authors.forename: J H
authors.initials: JH
authors.lastname: Check
mesh_terms: D000328:Adult; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D043373:Follicle Stimulating Hormone, Human; D005498:Follicular Phase / Q000502:physiology*; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives; D006801:Humans; D034461:Luteinization / Q000502:physiology*; D009865:Oocytes / Q000502:physiology*; D011994:Recombinant Proteins
chemical_list: D043373:Follicle Stimulating Hormone, Human; D011994:Recombinant Proteins; C571801:follitropin alfa; D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol; D005640:Follicle Stimulating Hormone; C061018:ganirelix