title: Fecal carriage of multi-drug resistant and extended spectrum β-lactamases producing E. coli in household pigeons, Bangladesh.
abstract: Antibiotic resistance and ESBL constitute a risk to human and animal health. Birds residing close to humans could mirror the spectrum of human associated antibiotic resistance. Household pigeons were screened in Bangladesh to shed light on human associated, as well as, environmental antibiotic resistance. Escherichia coli from pigeons (n=150) were tested against 11 antibiotics. 89% E. coli isolates were resistant to one or more critically important human antibiotics like ampicillin, cefadroxil, mecillinam, ciprofloxacin, gentamicin and tigecycline. No carbapenamase-producers were detected and the lower ESBL prevalence (5%) in pigeons. ESBL-producing E. coli isolates had blaCTX-M-15 genes. Pigeons shared some bacterial clones and had bird associated sequence types like E. coli ST1408. Fecal carriage of bacteria resistance of critically important human antibiotics, together with examples of shared genotypes among pigeons, indicate the human-birds and bird to bird transmissions are important in the epidemiology of antibiotic resistance.
authors.affiliation: Clinical Microbiology and Infectious Medicine, Department of Medical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden. Electronic address: badrul.hasan@medsci.uu.se.
authors.forename: Badrul
authors.initials: B
authors.lastname: Hasan
authors.affiliation: Department of Microbiology, Faculty of Veterinary Medicine, Chittagong Veterinary and Animal Sciences University, Khulshi, 4012 Chittagong, Bangladesh.
authors.forename: Kamrul
authors.initials: K
authors.lastname: Islam
authors.affiliation: Department of Microbiology, Faculty of Veterinary Medicine, Chittagong Veterinary and Animal Sciences University, Khulshi, 4012 Chittagong, Bangladesh.
authors.forename: Murshidul
authors.initials: M
authors.lastname: Ahsan
authors.affiliation: Department of Microbiology, Faculty of Veterinary Medicine, Chittagong Veterinary and Animal Sciences University, Khulshi, 4012 Chittagong, Bangladesh.
authors.forename: Zakir
authors.initials: Z
authors.lastname: Hossain
authors.affiliation: Clinical Microbiology and Infectious Medicine, Department of Medical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden.
authors.forename: Mahmudur
authors.initials: M
authors.lastname: Rashid
authors.affiliation: Department of Microbiology, Faculty of Veterinary Medicine, Chittagong Veterinary and Animal Sciences University, Khulshi, 4012 Chittagong, Bangladesh.
authors.forename: Bibhas
authors.initials: B
authors.lastname: Talukder
authors.affiliation: Enteric & Food Microbiology Laboratory, Laboratory Sciences Division, International Center for Diarrhoeal Disease Research, Dhaka 1000, Bangladesh.
authors.forename: Kabir Uddin
authors.initials: KU
authors.lastname: Ahmed
authors.affiliation: Clinical Microbiology and Infectious Medicine, Department of Medical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden.
authors.forename: Björn
authors.initials: B
authors.lastname: Olsen
authors.affiliation: Department of Microbiology, Faculty of Veterinary Medicine, Chittagong Veterinary and Animal Sciences University, Khulshi, 4012 Chittagong, Bangladesh.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Abul Kashem
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001459:Bangladesh; D010856:Columbidae / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology* / Q000235:genetics; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission; D029968:Escherichia coli Proteins / Q000235:genetics; D005243:Feces / Q000382:microbiology*; D005838:Genotype; D006801:Humans; D015995:Prevalence; D001618:beta-Lactamases / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D029968:Escherichia coli Proteins; D001618:beta-Lactamases
keywords: Antibiotic resistance; E. coli; ESBL; Pigeon; bla(CTX-M-15)