title: CYP2B6-G516T genotype influences plasma efavirenz concentration in a Hong Kong population, allowing potential individualization of therapy.
authors.affiliation: Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong, China.
authors.forename: C M
authors.initials: CM
authors.lastname: Naftalin
authors.forename: K C W
authors.initials: KC
authors.lastname: Chan
authors.forename: K H
authors.initials: KH
authors.lastname: Wong
authors.forename: S W
authors.initials: SW
authors.lastname: Cheung
authors.forename: R C Y
authors.initials: RC
authors.lastname: Chan
authors.forename: S S
authors.initials: SS
authors.lastname: Lee
mesh_terms: D000328:Adult; D000480:Alkynes; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics*; D048588:Benzoxazines / Q000097:blood* / Q000627:therapeutic use; D003521:Cyclopropanes; D065702:Cytochrome P-450 CYP2B6; D005260:Female; D005838:Genotype; D015658:HIV Infections / Q000097:blood* / Q000188:drug therapy / Q000235:genetics; D015497:HIV-1; D006723:Hong Kong; D006801:Humans; D008297:Male; D008875:Middle Aged; D018894:Reverse Transcriptase Inhibitors / Q000097:blood* / Q000627:therapeutic use
chemical_list: D000480:Alkynes; D048588:Benzoxazines; D003521:Cyclopropanes; D018894:Reverse Transcriptase Inhibitors; D001189:Aryl Hydrocarbon Hydroxylases; C585599:CYP2B6 protein, human; D065702:Cytochrome P-450 CYP2B6; C098320:efavirenz