title: Obesity in childhood and adolescence, genetic factors.
abstract: Obesity and overweight are a pandemic phenomenon in the modern world. Childhood and adolescent obesity often ends up in obesity in adults. The costs of obesity and its consequences are staggering for any society, crippling for countries in development. The etiology is complex, but most often idiopathic. Hormonal, syndromic and medication-induced obesity are well investigated. Genetic causes are increasingly described. Novel technologies such as whole exome sequencing identify ever more candidate genes influencing or causing obesity. All insights into the complex problem of obesity in a team approach to treatment: diet, psychology, medications and surgery. We briefly review epidemiology, etiology, consequences and treatment approaches in childhood and adolescent obesity, with special emphasis on emerging knowledge of its genetics.
authors.affiliation: Medical Faculty Skopje, 50 Divizija BB, 1000 Skopje, R. Macedonia.
authors.forename: Rexhep
authors.initials: R
authors.lastname: Memedi
authors.forename: Velibor
authors.initials: V
authors.lastname: Tasic
authors.forename: Erieta
authors.initials: E
authors.lastname: Nikolic
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Jancevska
authors.forename: Zoran
authors.initials: Z
authors.lastname: Gucev
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D015897:Comorbidity; D005260:Female; D005819:Genetic Markers; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D063766:Pediatric Obesity / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics* / Q000503:physiopathology / Q000628:therapy; D010641:Phenotype; D011379:Prognosis; D012307:Risk Factors
chemical_list: D005819:Genetic Markers