title: [Short-term impact of air pollution among Italian cities covered by the EpiAir2 project].
abstract: OBJECTIVE
  to estimate the short-term impact of air pollutants on adult population of 23 Italian cities on the calendar period 2006- 2009 as part of the EpiAir2 project.
  
  
  METHODS
  for each city, the short-term impact of air pollution on mortality was estimated. In particular, it was calculated the number of deaths attributable to particulate matter levels (PM10 and PM2.5) exceeding different thresholds deriving from the European Union legislation and the World Health Organization guidelines (PM10: 20 and 40 µg/m(3), reduction of 20% up to 20 µg/m(3) and more than 35 days per year with daily average above 50 µg/m(3); PM2.5: 10, 18 and 25 µg/m(3), reduction of 20% up to 18 µg/m(3)). The impact evaluation was done combining the effect estimates of air pollutant, the observed mortality level and the air pollution concentration measured by the ambient monitors. Regarding effects, the posterior city-specific distributions arising from a Bayesian metanalysis was employed. Uncertainty around the impact estimates was obtained by Monte Carlo methods.
  
  
  RESULTS
  overall, in the 23 cities considered in the present study attributable deaths to short-term effects of PM10 concentrations above 20 µg/m(3) as annual average and of PM2.5 concentrations above 10 µg/m(3) on the period 2006-2009 was respectively 0.9% (assuming independence among cities the 80% credibility interval is 0.4-1.4) and 0.8% (80%CrI 0.2-1.3) of natural mortality. The impact was larger for the cities of the river Po valley, the Florence area and the large conurbations of Rome, Naples and Palermo: considering PM10 1.0% (80%CrI 0.4-1.5) vs. 0.4% (80%CrI 0.2-0.7) of natural deaths among the other cities in the study. Pollution reduction actions as prescribed by the European Union legislation, i.e. a 20% reduction up to 20 µg/m(3) for PM10 and up to 18 µg/m(3) for PM2.5, would have saved, over all the cities covered by this study, 42% and 51% of all attributable deaths, respectively.
  
  
  CONCLUSIONS
  during the study period, air pollution exposure was responsible for a relevant impact on mortality in the enrolled cities. Policies based on percent reduction of PM10 and PM2.5 as prescribed by the European Union could substantially reduce the short term impact on population mortality.
authors.affiliation: Dipartimento di satistica, informatica e applicazioni "G. Parenti", Università di Firenze; Unità di biostatistica, Istituto per lo studio e la prevenzione oncologica (ISPO), Firenze abiggeri@disia.unifi.it.
authors.forename: Michela
authors.initials: M
authors.lastname: Baccini
authors.forename: Annibale
authors.initials: A
authors.lastname: Biggeri
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects* / Q000032:analysis; D000397:Air Pollution / Q000009:adverse effects* / Q000032:analysis; D002423:Cause of Death; D002947:Cities; D004784:Environmental Monitoring; D062665:Epidemiological Monitoring; D006801:Humans; D007558:Italy; D052638:Particulate Matter / Q000009:adverse effects* / Q000032:analysis; D013997:Time Factors; D014504:Urban Health
chemical_list: D000393:Air Pollutants; D052638:Particulate Matter