title: Schwannoma of the rectum: A case report and literature review.
abstract: Schwannoma is a tumor originating from the Schwann cells. Gastrointestinal schwannomas are uncommon stromal tumors of the intestinal tract and, in particular, rectal schwannomas are extremely rare. In fact, it is well established that schwannomas appear more frequently in the stomach and in the small intestine, while location in the colon or in the rectum is uncommon. Reading the literature, only few cases of rectal schwannoma have been reported. Their diagnosis is confirmed by the immunohistochemical panel (S-100 protein). When these tumors are located in the colon and in the rectum, radical excision with wide margins is mandatory, due to their tendency to recur locally or become malignant, if left untreated. In the present study, we describe a case of a rectal schwannoma occured in a 72-year-old man, presented as a small polypoid lesion, which was successfully removed in toto by hot-biopsy, during the same endoscopy, due to the dimensons. No recurrence of the lesion was observed after 6 mo of follow-up.
authors.affiliation: Maddalena Zippi, Roberta Pica, Claudio Cassieri, Eleonora Veronica Avallone, Giuseppe Occhigrossi, Department of Gastroenterology and Digestive Endoscopy, Sandro Pertini Hospital, 00157 Rome, Italy.
authors.forename: Maddalena
authors.initials: M
authors.lastname: Zippi
authors.forename: Roberta
authors.initials: R
authors.lastname: Pica
authors.forename: Renzo
authors.initials: R
authors.lastname: Scialpi
authors.forename: Claudio
authors.initials: C
authors.lastname: Cassieri
authors.forename: Eleonora Veronica
authors.initials: EV
authors.lastname: Avallone
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Occhigrossi
keywords: Immunohistochemistry; Rectum; S-100 protein; Schwannoma; Treatment