title: Synthesis and binding ability of molecular probes based on a phenanthroline derivative: theory and experiment.
abstract: A fluorescent and colorimetric molecular probe containing phenol groups has been designed and synthesized. The anion binding ability was evaluated for biolgically important anions (F-, Cl-, Br-, I-, AcO- and H2PO4-) by theoretical investigation, UV-Vis and fluorescence spectroscopy and 1H-NMR titration experiments. Results indicated the probe showed strong binding ability for H2PO4- without the interference of other anions tested and the interaction process was accompanied by color changes. Theoretical investigation analysis revealed that intramolecular hydrogen bonds existed in the structure of the probe and the roles of molecular frontier orbitals in molecular interplay were determined.
authors.affiliation: Department of Chemistry, Xinxiang Medical University, Xinxiang 453003, Henan, China. xuefangshang@126.com.
authors.forename: Xuefang
authors.initials: X
authors.lastname: Shang
authors.forename: Yingling
authors.initials: Y
authors.lastname: Wang
authors.forename: Xiaofang
authors.initials: X
authors.lastname: Wei
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Fu
authors.forename: Jinlian
authors.initials: J
authors.lastname: Zhang
authors.forename: Xiufang
authors.initials: X
authors.lastname: Xu
mesh_terms: D000838:Anions / Q000737:chemistry; D004396:Coloring Agents / Q000138:chemical synthesis / Q000737:chemistry*; D006860:Hydrogen Bonding; D008956:Models, Chemical; D008958:Models, Molecular; D008968:Molecular Conformation; D015335:Molecular Probes / Q000138:chemical synthesis / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D010618:Phenanthrolines / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000838:Anions; D004396:Coloring Agents; D015335:Molecular Probes; D010618:Phenanthrolines