title: Effects of combined exercise training on immunological, physical and biochemical parameters in individuals with HIV/AIDS.
abstract: The practice of exercise has shown to be beneficial to quality of life of individuals with HIV/AIDS. Thus, the present study analysed the effects of a combined exercise training in persons living with HIV/AIDS. Ten participants participated in the present study. The following variables were analysed: viral load and cell counts for TCD4+/TCD8; maximal oxygen consumption (VO2max); total mass, absolute fat mass, relative fat mass, absolute lean mass, relative lean mass and body mass index; fasting glycaemia, fasting insulinaemia, homeostatic model assessment (HOMA) index (insulin resistance - homeostatic model assessment (IR-HOMA)); total cholesterol, triglycerides, high-density lipoprotein (HDL), very low-density lipoprotein (VLDL), low-density lipoprotein (LDL); superoxide dismutase, catalase, glutathione peroxidase activities; thiobarbituric acid reactive substances. The combined exercise training consisted of resistance exercises plus aerobic training (60 min · session(-1), three times per week, during 20 weeks). The number of TCD4+ cells, absolute lean mass and relative lean mass, muscle strength for the 45° leg press, seated row and triceps extension, HDL-c levels as well as VO2max increased post-training. The activity of superoxide dismutase, catalase, glutathione peroxidase enzymes and thiobarbituric acid reactive substances levels were diminished post-training. Finally, it can be concluded that combined exercise training is able to change positively several variables related to health of individuals with HIV/AIDS, mainly the immune system as well as antioxidant mechanisms re-establishment.
authors.affiliation: a Federal University of Mato Grosso (UFMT) Cuiabá , Brazil.
authors.forename: Alesandro
authors.initials: A
authors.lastname: Garcia
authors.forename: Géssica Alves
authors.initials: GA
authors.lastname: Fraga
authors.forename: Roberto Carlos
authors.initials: RC
authors.lastname: Vieira
authors.forename: Carolina Mendes Santos
authors.initials: CM
authors.lastname: Silva
authors.forename: Joice Cristina Dos Santos
authors.initials: JC
authors.lastname: Trombeta
authors.forename: James Wilfred
authors.initials: JW
authors.lastname: Navalta
authors.forename: Jonato
authors.initials: J
authors.lastname: Prestes
authors.forename: Fabricio Azevedo
authors.initials: FA
authors.lastname: Voltarelli
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology* / Q000628:therapy* / Q000821:virology; D050154:Adiposity / Q000502:physiology; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D016516:CD4-CD8 Ratio; D002374:Catalase / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D005081:Exercise Therapy; D005979:Glutathione Peroxidase / Q000097:blood; D006487:Hemostasis; D006801:Humans; D007328:Insulin / Q000097:blood; D008875:Middle Aged; D053580:Muscle Strength; D010101:Oxygen Consumption; D013482:Superoxide Dismutase / Q000097:blood; D013858:Thiobarbiturates / Q000097:blood; D019562:Viral Load
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D007328:Insulin; D013858:Thiobarbiturates; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; C029684:thiobarbituric acid