title: Aldosterone testing: evaluation of a novel automated immunoassay.
abstract: Aldosterone levels are increased in primary aldosteronism (PA) and might be triggered in several cardiovascular disorders. The aim of our study was to assess the analytical validity of a novel automated aldosterone immunoassay. Method comparison was also performed with a reference radioimmunoassay. We report for the first time the analytical validity of the LIAISON® aldosterone automated immunoassay. Such automated assay might therefore facilitate the screening of PA and risk stratification of cardiovascular diseases.
authors.affiliation: Department of Laboratory Medicine and.
authors.forename: Flavie
authors.initials: F
authors.lastname: Derlet
authors.forename: Thibault
authors.initials: T
authors.lastname: Lepoutre
authors.forename: Damien
authors.initials: D
authors.lastname: Gruson
mesh_terms: D000450:Aldosterone / Q000097:blood / Q000652:urine*; D016022:Case-Control Studies; D006801:Humans; D006929:Hyperaldosteronism / Q000097:blood / Q000175:diagnosis* / Q000652:urine; D006973:Hypertension / Q000097:blood / Q000175:diagnosis* / Q000652:urine; D007118:Immunoassay; D057230:Limit of Detection; D011933:Reagent Kits, Diagnostic; D012016:Reference Values
chemical_list: D011933:Reagent Kits, Diagnostic; D000450:Aldosterone