title: Association between periodontal disease and adverse pregnancy outcomes in a cohort of pregnant women in Jordan.
abstract: BACKGROUND
  The relationship between periodontal disease (PD) and adverse pregnancy outcomes remain unclear. The authors' objective was to assess the risk of adverse pregnancy outcomes in Jordanian women with periodontal disease compared to those without.
  
  
  METHODS
  Between April 2009 and June 2010, 277 pregnant women with no systemic diseases at gestational age < 20 weeks were enrolled in the study. Dental and oral health examination was performed at enrollment after demographic, medical, and obstetrical information were recorded. Pregnancy outcomes were obtained by phone contact and review of medical records.
  
  
  RESULTS
  The incidence of periodontal disease in the pregnant women enrolled was 31%. Women with PD were at higher risk for developing preeclampsia (PE), preterm birth (PB), and low birth weight (LBW). The rate of PE in women with PD was 18.6% compared to 7.3% in the control group (p = 0.005) (OR = 2.7, 95% CI: 1.2, 6.0). The OR for PB was (4.4, 95% CI: 1.7, 11.7) and for LBW was (3.5, 95% CI: 1.6, 7.5).
  
  
  CONCLUSIONS
  PD is associated with increased risk of PE, PB, and LBW in healthy Jordanian women.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan. halchalabi@yahoo.com
authors.forename: H A
authors.initials: HA
authors.lastname: Alchalabi
authors.forename: R
authors.initials: R
authors.lastname: Al Habashneh
authors.forename: O Al
authors.initials: OA
authors.lastname: Jabali
authors.forename: Y S
authors.initials: YS
authors.lastname: Khader
mesh_terms: D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007597:Jordan / Q000453:epidemiology; D008875:Middle Aged; D009909:Oral Health; D010510:Periodontal Diseases / Q000453:epidemiology*; D010518:Periodontitis / Q000453:epidemiology; D011225:Pre-Eclampsia / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000453:epidemiology; D055815:Young Adult