title: Intelligence deficits in Chinese patients with brain tumor: the impact of tumor resection.
abstract: BACKGROUND
  Intelligence is much important for brain tumor patients after their operation, while the reports about surgical related intelligence deficits are not frequent. It is not only theoretically important but also meaningful for clinical practice.
  
  
  METHODS
  Wechsler Adult Intelligence Scale was employed to evaluate the intelligence of 103 patients with intracranial tumor and to compare the intelligence quotient (IQ), verbal IQ (VIQ), and performance IQ (PIQ) between the intracerebral and extracerebral subgroups.
  
  
  RESULTS
  Although preoperative intelligence deficits appeared in all subgroups, IQ, VIQ, and PIQ were not found to have any significant difference between the intracerebral and extracerebral subgroups, but with VIQ lower than PIQ in all the subgroups. An immediate postoperative follow-up demonstrated a decline of IQ and PIQ in the extracerebral subgroup, but an improvement of VIQ in the right intracerebral subgroup. Pituitary adenoma resection exerted no effect on intelligence. In addition, age, years of education, and tumor size were found to play important roles.
  
  
  CONCLUSIONS
  Brain tumors will impair IQ, VIQ, and PIQ. The extracerebral tumor resection can deteriorate IQ and PIQ. However, right intracerebral tumor resection is beneficial to VIQ, and transsphenoidal pituitary adenoma resection performs no effect on intelligence.
authors.affiliation: Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Shen
authors.forename: Rong
authors.initials: R
authors.lastname: Xie
authors.forename: Xiaoyun
authors.initials: X
authors.lastname: Cao
authors.forename: Weimin
authors.initials: W
authors.lastname: Bao
authors.forename: Bojie
authors.initials: B
authors.lastname: Yang
authors.forename: Ying
authors.initials: Y
authors.lastname: Mao
authors.forename: Chao
authors.initials: C
authors.lastname: Gao
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000150:complications* / Q000601:surgery; D016022:Case-Control Studies; D002681:China; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008607:Intellectual Disability / Q000175:diagnosis / Q000209:etiology*; D007360:Intelligence; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000009:adverse effects; D011184:Postoperative Period; D057234:Preoperative Period