title: Insights into the mechanisms of sclerostin action in regulating bone mass accrual.
authors.affiliation: Center for Skeletal Disease and Tumor Metastasis, Van Andel Research Institute, Grand Rapids, MI, USA.
authors.forename: Bart O
authors.initials: BO
authors.lastname: Williams
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D001842:Bone and Bones / Q000503:physiopathology*; D004195:Disease Models, Animal; D006023:Glycoproteins / Q000172:deficiency / Q000235:genetics*; D036341:Intercellular Signaling Peptides and Proteins; D060492:Low Density Lipoprotein Receptor-Related Protein-5 / Q000172:deficiency / Q000502:physiology*; D060488:Low Density Lipoprotein Receptor-Related Protein-6 / Q000502:physiology*; D010013:Osteogenesis Imperfecta / Q000503:physiopathology*; D060449:Wnt Signaling Pathway / Q000502:physiology*
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D006023:Glycoproteins; D036341:Intercellular Signaling Peptides and Proteins; D060492:Low Density Lipoprotein Receptor-Related Protein-5; D060488:Low Density Lipoprotein Receptor-Related Protein-6; C555483:Lrp5 protein, mouse; C555476:Lrp6 protein, mouse; C486030:Sost protein, mouse