title: Is SPME a destination or just another station for bioanalysis?
abstract: This article reviews the solid-phase microextraction technique and its potential to revolutionize bioanalysis in terms of combining sampling, sample preparation and extraction in one step with no blood withdrawal. Possible hurdles facing the technology when implemented in a pharmaceutical setting will be covered and the author will provide an outlook on the future of solid-phase microextraction as a novel microsampling technique for bioanalysis.
authors.affiliation: Platform Technologies & Science, Drug Metabolism & Pharmacokinetics, GlaxoSmithKline Research & Development, Ware, Hertfordshire, SG12 0DP, UK. sheelan.2.ahmad@gsk.com.
authors.forename: Sheelan
authors.initials: S
authors.lastname: Ahmad
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000032:analysis; D055808:Drug Discovery / Q000295:instrumentation / Q000379:methods; D006801:Humans; D055432:Metabolomics / Q000295:instrumentation / Q000379:methods; D052617:Solid Phase Microextraction / Q000295:instrumentation / Q000379:methods*; D013048:Specimen Handling
chemical_list: D015415:Biomarkers