title: Preparation and characterization of PEG-Mentha oil nanoparticles for housefly control.
abstract: Nanoparticles of Mentha × piperita essential oil were prepared by melt-dispersion method. The nanoparticles prepared at varying oil doses (5-10%, w/v) showed an encapsulation efficiency of 78.2-83.4%, while the oil load was observed to range between 3.64 and 7.46%. The average particle size of the nanoparticles varied between 226 and 331 nm, while polydispersity index showed variation between 0.547 and 1.000. DSC analysis indicated endothermic reaction during formation of nanoparticles, while a 2-term exponential kinetic model was followed during oil release. Nanoparticles showed considerable mortality against housefly larvae in lab (100%) as well as simulated field condition after first week (93%) and 6th week (57%) of application. This was the first study utilizing controlled release property of nanoparticles to formulate a cost effective product for breeding site application against housefly.
authors.affiliation: Applied Microbiology Laboratory, Centre for Rural Development & Technology, Indian Institute of Technology Delhi, New Delhi 110 016, India.
authors.forename: Peeyush
authors.initials: P
authors.lastname: Kumar
authors.affiliation: Applied Microbiology Laboratory, Centre for Rural Development & Technology, Indian Institute of Technology Delhi, New Delhi 110 016, India.
authors.forename: Sapna
authors.initials: S
authors.lastname: Mishra
authors.affiliation: Applied Microbiology Laboratory, Centre for Rural Development & Technology, Indian Institute of Technology Delhi, New Delhi 110 016, India. Electronic address: anushree@rdat.iitd.ac.in.
authors.forename: Anushree
authors.initials: A
authors.lastname: Malik
authors.affiliation: Applied Microbiology Laboratory, Centre for Rural Development & Technology, Indian Institute of Technology Delhi, New Delhi 110 016, India.
authors.forename: Santosh
authors.initials: S
authors.lastname: Satya
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D006793:Houseflies / Q000187:drug effects*; D007300:Insect Control; D007814:Larva / Q000187:drug effects; D027541:Mentha / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D011092:Polyethylene Glycols / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D009822:Oils, Volatile; D011092:Polyethylene Glycols
keywords: Encapsulation efficiency; Housefly; Mentha×piperita; Nanoparticles; PEG