title: Diabetic neuropathy.
abstract: Diabetic neuropathy (DN) is the most common and troublesome complication of diabetes mellitus, leading to the greatest morbidity and mortality and resulting in a huge economic burden for diabetes care. The clinical assessment of diabetic peripheral neuropathy and its treatment options are multifactorial. Patients with DN should be screened for autonomic neuropathy, as there is a high degree of coexistence of the two complications. A review of the clinical assessment and treatment algorithms for diabetic neuropathy, painful neuropathy, and autonomic dysfunction is provided.
authors.affiliation: Internal Medicine, Strelitz Diabetes Center, Eastern Virginia Medical School, 855 West Brambleton Avenue, Norfolk, VA 23510, USA. Electronic address: VinikAI@evms.edu.
authors.forename: Aaron I
authors.initials: AI
authors.lastname: Vinik
authors.forename: Marie-Laure
authors.initials: ML
authors.lastname: Nevoret
authors.forename: Carolina
authors.initials: C
authors.lastname: Casellini
authors.forename: Henri
authors.initials: H
authors.lastname: Parson
mesh_terms: D001342:Autonomic Nervous System Diseases / Q000209:etiology / Q000628:therapy; D002318:Cardiovascular Diseases / Q000150:complications / Q000473:pathology; D003929:Diabetic Neuropathies / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D017408:Guidelines as Topic; D006801:Humans; D006943:Hyperglycemia / Q000150:complications / Q000473:pathology; D009437:Neuralgia / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology
keywords: Diabetes mellitus; Diabetic nephropathy; Painful neuropathy; Pregabalin