title: Feto-maternal outcomes in women with and without gestational diabetes mellitus according to the International Association of Diabetes and Pregnancy Study Groups (IADPSG) diagnostic criteria.
abstract: BACKGROUND
  Gestational diabetes mellitus (GDM) is responsible for majority of pregnancies complicated with diabetes mellitus. Both the screening (universal vs. selective) and the diagnostic criteria of GDM has been the subject of considerable controversy.
  
  
  METHODS
  This prospective cohort study was undertaken at Pondicherry Institute of Medical Sciences, Puducherry from August 2011 to July 2012. All the patients attending antenatal clinic underwent oral glucose tolerance test (OGTT) with 75g of anhydrous glucose between 24 and 32 weeks of gestation. Those patients diagnosed as GDM according to IADPSG diagnostic criteria were treated with diet and physical activity with or without insulin. All the antenatal and perinatal outcomes were noted.
  
  
  RESULTS
  The prevalence of GDM in our study was 27% (83/304). Out of all the GDM patients, 87% (72/83) cases were diagnosed by raised FBS alone or with other two values. A significant family history of diabetes mellitus was found among GDM mothers compared to non-GDM group (10.8% vs. 3.6%, p=0.01). Insulin was required only in 8 patients for glycemic control. The GDM patients delivered at significantly lower gestational age (p=0.02) with more antenatal complications (25% vs. 12%, p=0.02). Among neonatal outcomes, there was a significant difference only in the need for NICU admission>24h between GDM and non-GDM groups (p=0.02).
  
  
  CONCLUSIONS
  The prevalence of GDM increases with universal screening using IADPSG diagnostic criteria in India. The antenatal complications are present in up to one fourth of these patients.
authors.affiliation: Department of Obstetrics and Gynecology, Pondicherry Institute of Medical Sciences, Puducherry, India. Electronic address: drprasant79@gmail.com.
authors.forename: Prasanta Kumar
authors.initials: PK
authors.lastname: Nayak
authors.forename: Subarna
authors.initials: S
authors.lastname: Mitra
authors.forename: Jaya Prakash
authors.initials: JP
authors.lastname: Sahoo
authors.forename: Mary
authors.initials: M
authors.lastname: Daniel
authors.forename: Agnes
authors.initials: A
authors.lastname: Mathew
authors.forename: Alaganandam
authors.initials: A
authors.lastname: Padma
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D016640:Diabetes, Gestational / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D005951:Glucose Tolerance Test; D006801:Humans; D007194:India / Q000453:epidemiology; D007231:Infant, Newborn; D008403:Mass Screening / Q000379:methods*; D008430:Maternal-Child Health Centers; D063868:Patient Outcome Assessment; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology; D011256:Pregnancy Outcome; D011254:Pregnancy in Diabetics / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology; D011296:Prenatal Diagnosis; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors
chemical_list: D001786:Blood Glucose
keywords: Gestational diabetes mellitus; International Association of Diabetes and Pregnancy Study Groups; Oral glucose tolerance test