title: Dibromoisobenzofuran as a formal equivalent of didehydroisobenzofuran: reactive platform for expeditious assembly of polycycles.
abstract: Two-directional annulation of dibromoisobenzofuran, a formal equivalent to didehydroisobenzofuran, was developed. Importantly, selective bromine-lithium exchange allows the tandem generation of benzynes and dual cycloadditions with two different arynophiles. Also described is the application to the synthesis of a substituted pentacene.
authors.affiliation: Department of Chemistry, School of Science and Technology, Kwansei Gakuin University , 2-1 Gakuen, Sanda, Hyogo 669-1337, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Haneda
authors.forename: Shohei
authors.initials: S
authors.lastname: Eda
authors.forename: Masato
authors.initials: M
authors.lastname: Aratani
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Hamura
mesh_terms: D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D001572:Benzofurans / Q000737:chemistry*; D003500:Cyclization; D015394:Molecular Structure; D009279:Naphthacenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001555:Benzene Derivatives; D001572:Benzofurans; D009279:Naphthacenes; C524146:benzyne; C523499:pentacene