title: Global comparison of gene expression between subcutaneous and intramuscular adipose tissue of mature Erhualian pig.
abstract: Adipose tissue plays an important role in energy metabolism and related diseases. The content of intramuscular fat significantly influences the pork quality. In this study, the whole gene expression of dorsal subcutaneous (s.c.) adipose tissue and intramuscular (i.m.) adipose tissue isolated from longissimus dorsi muscle tissue were compared using Affymetrix Gene-Chip microarray technology. The result revealed that 1228 genes were more highly expressed in s.c. adipose tissue, whereas 965 genes were higher expressed in i.m. adipose tissue. We found that the s.c. adipose tissue had a stronger capacity of lipid metabolism and fatty acid metabolism compared with i.m. adipose tissue, and angiopoietin-like-4, neuronatin, neuron-derived orphan receptor-1 alfa, and chloride intracellular channel 5 may play important roles in the regulation of fat deposition between i.m. and s.c. adipose tissues.
authors.affiliation: College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, China.
authors.forename: W X
authors.initials: WX
authors.lastname: Sun
authors.forename: H H
authors.initials: HH
authors.lastname: Wang
authors.forename: B C
authors.initials: BC
authors.lastname: Jiang
authors.forename: Y Y
authors.initials: YY
authors.lastname: Zhao
authors.forename: Z R
authors.initials: ZR
authors.lastname: Xie
authors.forename: K
authors.initials: K
authors.lastname: Xiong
authors.forename: J
authors.initials: J
authors.lastname: Chen
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D000818:Animals; D019295:Computational Biology / Q000379:methods; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D008297:Male; D018482:Muscle, Skeletal; D015203:Reproducibility of Results; D015398:Signal Transduction; D050151:Subcutaneous Fat / Q000378:metabolism; D013552:Swine