title: Systemic therapy of non-resectable metastatic melanoma.
abstract: In advanced metastatic melanoma (non-resectable stage III/IV), the prognosis still remains poor, with median survival times between six and twelve months. Systemic therapeutic approaches for metastatic melanoma include chemotherapy, immunotherapy, immunochemotherapy, small molecules and targeted therapy. In this review, we will focus on the various treatment modalities as well as new agents used for targeted therapy.
authors.affiliation: Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Germany. jochen.utikal@umm.de.
authors.forename: Azadeh
authors.initials: A
authors.lastname: Orouji
authors.forename: Sergij
authors.initials: S
authors.lastname: Goerdt
authors.forename: Jochen
authors.initials: J
authors.lastname: Utikal