title: Prevalence and associated factors of T-score discordance between different sites in Iranian patients with spinal cord injury.
abstract: OBJECTIVE
  The present study was conducted to determine the prevalence of T-score discordance and its risk factors in a group of patients with spinal cord injury in a university teaching hospital in the Iranian capital of Tehran.
  
  
  METHODS
  This cross-sectional study was conducted on paraplegic men undergoing bone density testing in an outpatient clinic at a hospital in the Iranian capital, Tehran, between March 2011 and 2012. A questionnaire on demographic and anthropometric characteristics, including age, height, weight, engagement in physical activity and personal smoking habits, was filled out for each subject. All the subjects underwent bone mineral density measurement and blood samples were sent for laboratory testing.
  
  
  RESULTS
  Major T-score discordance between two sites was noted in 54 (41.22%) patients. Multivariate logistic regression revealed that every unit increase in serum calcium levels, as the only factor influencing T-score discordance, was associated with a 2.49-fold increased risk in T-score discordance in the area. As for the spine and radius, BMI was the only influencing factor as every unit increase in BMI was associated with a 14% lower risk for T-score discordance in these regions. Body mass index was the only factor, based on the multivariate model, affecting the risk of developing T-score discordance between two sites.
  
  
  CONCLUSIONS
  Our study revealed the high prevalence of T-score discordance in patients with spinal cord injury. Physicians should therefore be encouraged to perform BMD at three sites when visiting patients with such injuries.
authors.affiliation: Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: S A
authors.initials: SA
authors.lastname: Alavizadeh
authors.affiliation: Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: M R
authors.initials: MR
authors.lastname: Mohajeri-Tehrani
authors.affiliation: Rheumatology Department, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: A
authors.initials: A
authors.lastname: Rostamian
authors.affiliation: Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: H R
authors.initials: HR
authors.lastname: Aghaei Meybodi
authors.affiliation: 1] Department of Public Health, Alborz University of Medical Sciences, Karaj, Iran [2] Department of Epidemiology, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Qorbani
authors.affiliation: Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: A A
authors.initials: AA
authors.lastname: Keshtkar
authors.affiliation: Rheumatology Department, Khatamolanbia Hospital, Shahed University of Medical Sciences, Tehran, Iran.
authors.forename: S S
authors.initials: SS
authors.lastname: Panahi
authors.affiliation: Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: F
authors.initials: F
authors.lastname: Rahdari
authors.affiliation: Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: P
authors.initials: P
authors.lastname: Khashayar
mesh_terms: D000367:Age Factors; D001774:Blood Chemical Analysis; D015992:Body Mass Index; D015519:Bone Density; D002118:Calcium / Q000097:blood; D003430:Cross-Sectional Studies; D006801:Humans; D007492:Iran / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010024:Osteoporosis / Q000175:diagnosis* / Q000453:epidemiology* / Q000378:metabolism; D010264:Paraplegia / Q000453:epidemiology* / Q000209:etiology / Q000378:metabolism; D015995:Prevalence; D013119:Spinal Cord Injuries / Q000150:complications / Q000453:epidemiology* / Q000378:metabolism
chemical_list: D002118:Calcium