title: Application of the defect area in transcatheter closure of atrial septal defect.
abstract: OBJECTIVE
  It was our aim to evaluate whether the defect area plays a crucial role in successful device closure of atrial septal defects (ASDs).
  
  
  METHODS
  The long and short diameters of the defect were measured on en-face images. The defect area was then measured by planimetry. The device size compared to the defect length and defect area was analyzed in each group.
  
  
  RESULTS
  There were 22 patients in the circular group and 45 patients in the noncircular group. The defect area did not differ between the groups (201.6 ± 107.1 vs. 245.6 ± 127.6 mm(2)). Although the length between the device size and the long diameter differed between the groups (3.4 ± 2.0 vs. 0.8 ± 3.7 mm; p = 0.003), there was no difference in the ratio of the device area compared to the defect area, which was constant even in the noncircular defect (1.73 ± 0.41 vs. 1.72 ± 0.53 mm(2); p = 0.947). The device size was positively correlated with the defect area (p < 0.01).
  
  
  CONCLUSIONS
  The defect area measured by planimetry on en-face images might be useful in selecting the device size for transcatheter closure of ASDs.
authors.affiliation: Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Jinyoung
authors.initials: J
authors.lastname: Song
authors.forename: I-Seok
authors.initials: IS
authors.lastname: Kang
authors.forename: Sung-A
authors.initials: SA
authors.lastname: Chang
authors.forename: June
authors.initials: J
authors.lastname: Huh
authors.forename: Seung Woo
authors.initials: SW
authors.lastname: Park
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004867:Equipment Design; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055989:Septal Occluder Device; D055815:Young Adult