title: [Communication with ALS patients: neurosurgical approach].
abstract: By progression of the disease, motor neurons degenerate in patients with amyotrophic lateral sclerosis (ALS) eventually lose nearly all voluntary muscles in the body. They are awake and aware but cannot move or communicate (locked-in state). Since the function of the brain is preserved, one possible measure to support their communication is to interpret their motor intention by decoding (deciphering) brain signals and present it with external devices. This technology called "brain-machine interface (BMI)" is now close to clinical use in Japan and USA.In our system, we record electrocorticogram (ECoG) obtained with subudural electrodes during their motor imagery, decode it and determine the movement they intended. So far, one patient of ALS with severe paralysis, implanted with this electrodes, successfully operated the PC communication tool only by thinking.
authors.affiliation: Department of Neurosurgery, Osaka University Medical School.
authors.forename: Toshiki
authors.initials: T
authors.lastname: Yoshimine
authors.forename: Takufumi
authors.initials: T
authors.lastname: Yanagisawa
authors.forename: Jin-Ichi
authors.initials: J
authors.lastname: Sawada
authors.forename: Takanori
authors.initials: T
authors.lastname: Hazama
authors.forename: Hideki
authors.initials: H
authors.lastname: Mochizuki
authors.forename: Masayuki
authors.initials: M
authors.lastname: Hirata
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000523:psychology* / Q000534:rehabilitation*; D062207:Brain-Computer Interfaces; D003142:Communication; D003143:Communication Devices for People with Disabilities; D004567:Electrodes, Implanted; D004569:Electroencephalography; D004867:Equipment Design; D006801:Humans; D009493:Neurosurgery / Q000295:instrumentation* / Q000379:methods*; D013850:Thinking / Q000502:physiology*