title: Severe granulomatous reaction associated with hypercalcemia occurring after silicone soft tissue augmentation of the buttocks: a case report.
abstract: Liquid silicone is a permanent filler. Its use to augment soft tissues for aesthetic purposes was widespread worldwide in the 1960s. Although initially considered to be biologically inert, this substance may cause, after its injection, an inflammatory granulomatous effect of variable severity and, in very rare cases, a severe hypercalcemia, which can be life threatening. The reported case highlights the well-known physiopathology of hypercalcemia, and the various therapeutic options are discussed.
  
  
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authors.affiliation: Department of Plastic, Reconstructive and Hand Surgery, Hôpital St ROCH, Rue Pierre Devoluy, BP 1319, 06006, Nice Cedex, France. camuzard.olivier@hotmail.fr.
authors.forename: O
authors.initials: O
authors.lastname: Camuzard
authors.affiliation: Department of Plastic, Reconstructive and Hand Surgery, Hôpital St ROCH, Rue Pierre Devoluy, BP 1319, 06006, Nice Cedex, France.
authors.forename: P
authors.initials: P
authors.lastname: Dumas
authors.affiliation: Department of Plastic, Reconstructive and Hand Surgery, Hôpital St ROCH, Rue Pierre Devoluy, BP 1319, 06006, Nice Cedex, France.
authors.forename: R
authors.initials: R
authors.lastname: Foissac
authors.affiliation: Department of Plastic, Reconstructive and Hand Surgery, Hôpital St ROCH, Rue Pierre Devoluy, BP 1319, 06006, Nice Cedex, France.
authors.forename: J
authors.initials: J
authors.lastname: Fernandez
authors.affiliation: Department of Plastic, Reconstructive and Hand Surgery, Hôpital St ROCH, Rue Pierre Devoluy, BP 1319, 06006, Nice Cedex, France.
authors.forename: S
authors.initials: S
authors.lastname: David
authors.affiliation: Department of Plastic, Reconstructive and Hand Surgery, Hôpital St ROCH, Rue Pierre Devoluy, BP 1319, 06006, Nice Cedex, France.
authors.forename: T
authors.initials: T
authors.lastname: Balaguer
authors.affiliation: Department of Plastic, Reconstructive and Hand Surgery, Hôpital St ROCH, Rue Pierre Devoluy, BP 1319, 06006, Nice Cedex, France.
authors.forename: B
authors.initials: B
authors.lastname: Chignon-Sicard
authors.affiliation: Department of Plastic, Reconstructive and Hand Surgery, Hôpital St ROCH, Rue Pierre Devoluy, BP 1319, 06006, Nice Cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Dumontier
mesh_terms: D002081:Buttocks / Q000601:surgery*; D003357:Cosmetic Techniques; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D008875:Middle Aged; D012720:Severity of Illness Index; D012828:Silicones / Q000009:adverse effects*
chemical_list: D012828:Silicones