title: Scarring of lupus miliaris disseminatus faciei: treatment with a combination of trichloroacetic acid and carbon dioxide laser.
abstract: We present a case of a 35-year-old man having a 12-month history of multiple reddish-brown papules on the chin, forehead, cheeks, and eyelids. Histopathologic findings revealed epithelioid cell granulomas with central necrosis consistent with a diagnosis of lupus miliaris disseminatus faciei. After 9 months of combined treatment with ethambutol, rifampin, and pyrazinamide, most lesions gradually resolved but remained as severe disfiguring scars. After 10 sessions of treatments with 100% trichloroacetic acid and CO2 laser, the lupus miliaris disseminatus faciei scars have been much improved and the patient has never experienced a recurrence of disease during subsequent years of follow-up.
authors.affiliation: Department of Dermatology, College of Medicine, Kyung Hee University, Seoul, Korea.
authors.forename: Boo Kyoung
authors.initials: BK
authors.lastname: Kang
authors.forename: Min Kyung
authors.initials: MK
authors.lastname: Shin
mesh_terms: D000328:Adult; D001706:Biopsy; D002424:Caustics / Q000627:therapeutic use*; D002921:Cicatrix / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D003131:Combined Modality Therapy; D005148:Facial Dermatoses / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006099:Granuloma / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D054020:Lasers, Gas / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000295:instrumentation*; D008297:Male; D009336:Necrosis; D012867:Skin / Q000187:drug effects* / Q000473:pathology / Q000528:radiation effects*; D016896:Treatment Outcome; D014238:Trichloroacetic Acid / Q000627:therapeutic use*
chemical_list: D002424:Caustics; D014238:Trichloroacetic Acid
keywords: carbon dioxide laser; lupus miliaris disseminatus faciei; trichloroacetic acid