title: [Post-splenectomy complications in primary immune thrombocytopenia. Literature review and preventive measures].
abstract: Management of primary immune thrombocytopenia (ITP) has changed, and clinical practice broadens the use of thrombopoietin receptor agonists and anti-CD20 antibody as options for second-line therapy, as alternative to splenectomy. Splenectomy remains a successful, definitive curative treatment. The purpose of this review about the complications of the splenectomy, in the context of ITP, is to increase the awareness of clinicians towards the preventive measures, which are often not correctly applied.
authors.affiliation: Service de médecine interne, centre de référence des cytopénies auto-immunes de l'adulte, université Paris Est Créteil (UPEC), CHU Henri-Mondor, Assistance publique-Hôpitaux de Paris, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94000 Créteil, France. Electronic address: matthieu.mahevas@hmn.aphp.fr.
authors.forename: M
authors.initials: M
authors.lastname: Mahévas
authors.affiliation: Service de maladies infectieuses et tropicales, centre d'infectiologie Necker-Pasteur, IHU Imagine, hôpital Necker-Enfants-Malades, université René-Descartes, 149, rue de Sèvres, 75015 Paris, France.
authors.forename: H
authors.initials: H
authors.lastname: Coignard-Biehler
authors.affiliation: Service de médecine interne, centre de référence des cytopénies auto-immunes de l'adulte, université Paris Est Créteil (UPEC), CHU Henri-Mondor, Assistance publique-Hôpitaux de Paris, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94000 Créteil, France.
authors.forename: M
authors.initials: M
authors.lastname: Michel
authors.affiliation: Service de maladies infectieuses et tropicales, centre d'infectiologie Necker-Pasteur, IHU Imagine, hôpital Necker-Enfants-Malades, université René-Descartes, 149, rue de Sèvres, 75015 Paris, France.
authors.forename: O
authors.initials: O
authors.lastname: Lortholary
authors.affiliation: Service de médecine interne, centre de référence des cytopénies auto-immunes de l'adulte, université Paris Est Créteil (UPEC), CHU Henri-Mondor, Assistance publique-Hôpitaux de Paris, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94000 Créteil, France.
authors.forename: B
authors.initials: B
authors.lastname: Godeau
mesh_terms: D019072:Antibiotic Prophylaxis; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology; D007252:Influenza Vaccines; D022401:Meningococcal Vaccines; D009894:Opportunistic Infections / Q000209:etiology / Q000517:prevention & control; D022242:Pneumococcal Vaccines; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000601:surgery*; D013156:Splenectomy / Q000009:adverse effects*; D020246:Venous Thrombosis / Q000209:etiology / Q000517:prevention & control
chemical_list: D007252:Influenza Vaccines; D022401:Meningococcal Vaccines; D022242:Pneumococcal Vaccines
keywords: Complications; Mesures préventives; Preventive measures; Primary immune thrombocytopenia; Purpura thrombopénique immunologique; Splenectomy; Splénectomie