title: Annual banned-substance review: analytical approaches in human sports drug testing.
abstract: Monitoring the misuse of drugs and the abuse of substances and methods potentially or evidently improving athletic performance by analytical chemistry strategies is one of the main pillars of modern anti-doping efforts. Owing to the continuously growing knowledge in medicine, pharmacology, and (bio)chemistry, new chemical entities are frequently established and developed, various of which present a temptation for sportsmen and women due to assumed/attributed beneficial effects of such substances and preparations on, for example, endurance, strength, and regeneration. By means of new technologies, expanded existing test protocols, new insights into metabolism, distribution, and elimination of compounds prohibited by the World Anti-Doping Agency (WADA), analytical assays have been further improved in agreement with the content of the 2013 Prohibited List. In this annual banned-substance review, literature concerning human sports drug testing that was published between October 2012 and September 2013 is summarized and reviewed with particular emphasis on analytical approaches and their contribution to enhanced doping controls.
authors.affiliation: Center for Preventive Doping Research - Institute of Biochemistry, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933, Cologne, Germany; European Monitoring Center for Emerging Doping Agents, Cologne, Germany.
authors.forename: Mario
authors.initials: M
authors.lastname: Thevis
authors.forename: Tiia
authors.initials: T
authors.lastname: Kuuranne
authors.forename: Hans
authors.initials: H
authors.lastname: Geyer
authors.forename: Wilhelm
authors.initials: W
authors.lastname: Schänzer
mesh_terms: D045930:Anabolic Agents / Q000032:analysis; D002186:Cannabinoids / Q000032:analysis; D004300:Doping in Sports / Q000379:methods*; D006728:Hormones / Q000032:analysis; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000032:analysis; D058573:Performance-Enhancing Substances / Q000032:analysis; D015813:Substance Abuse Detection / Q000379:methods*
chemical_list: D045930:Anabolic Agents; D002186:Cannabinoids; D006728:Hormones; D036341:Intercellular Signaling Peptides and Proteins; D058573:Performance-Enhancing Substances
keywords: anabolic agents; blood analysis; doping; drugs; sport; urine analysis