title: [Liver and pulmonary metastases of the colorectal carcinoma - the experience of the Department of Surgery, University Hospital in Pilsen].
abstract: BACKGROUND
  Liver and pulmonary metastases of the colorectal carcinoma develop in about 20-70%, resp. in 10-22% patients with the colorectal carcinoma. Their treatment is still a matter of discussion. The aim of our study was to evaluate the results of surgical treatment as a part of the multimodal approach.
  
  
  METHODS
  30 patients with liver and pulmonary colorectal metastases were operated on between 2002 and 4/2013. The average age was 62.8 ± 10.7 years. 19 patients had metachronous and 11 synchronous metastases. The liver metastases preceded pulmonary in 14 cases, and vice versa in 5 patients. Both types of metastases developed in seven patients simultaneously. Liver resection was performed in 23, radiofrequency ablation (RFA) in 7 patients. Laser pulmonary metastasectomy was performed in 15, pulmonary resection in 14 and RFA in one patient. The liver procedure preceded pulmonary in 25 patients. 73.3% patients had adjuvant oncological treatment.
  
  
  RESULTS
  30 days mortality rate was 3.3% (N=1) for the actinomycotic sepsis complicated with MRSA infection. Morbidity rate was 10%. Recurrence of liver metastases developed in 6 patients. RFA was performed in all patients. The median of overall and disease free survival was 6.9, resp. 1.1 years.
  
  
  CONCLUSIONS
  Surgical treatment as a part of the multimodal treatment is the only radical treatment for patients with liver and pulmonary metastases. It offers good long-term results.
authors.forename: V
authors.initials: V
authors.lastname: Třeška
authors.forename: J
authors.initials: J
authors.lastname: Vodička
authors.forename: V
authors.initials: V
authors.lastname: Špidlen
authors.forename: T
authors.initials: T
authors.lastname: Skalický
authors.forename: J
authors.initials: J
authors.lastname: Fichtl
authors.forename: V
authors.initials: V
authors.lastname: Šimánek
authors.forename: J
authors.initials: J
authors.lastname: Šafránek
authors.forename: A
authors.initials: A
authors.lastname: Sutnar
authors.forename: J
authors.initials: J
authors.lastname: Brůha
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000556:secondary* / Q000601:surgery; D017115:Catheter Ablation; D015179:Colorectal Neoplasms / Q000473:pathology*; D003131:Combined Modality Therapy; D018153:Czech Republic / Q000453:epidemiology; D018572:Disease-Free Survival; D005260:Female; D006498:Hepatectomy; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery; D008175:Lung Neoplasms / Q000556:secondary* / Q000601:surgery; D008297:Male; D059146:Metastasectomy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology*; D012189:Retrospective Studies