title: Absent response of intracranial melanoma metastases harboring BRAF V600E sequence variation to vemurafenib.
authors.affiliation: Institute for Pathology, University Hospital Basel, University of Basel, Switzerland.
authors.forename: Donato
authors.initials: D
authors.lastname: D'Alonzo
authors.forename: Katharina
authors.initials: K
authors.lastname: Glatz
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics / Q000556:secondary*; D017809:Fatal Outcome; D018698:Glutamic Acid; D006801:Humans; D007078:Ileal Neoplasms / Q000556:secondary; D007150:Immunohistochemistry; D007211:Indoles / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics / Q000556:secondary*; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics*; D012878:Skin Neoplasms / Q000235:genetics / Q000473:pathology*; D013449:Sulfonamides / Q000627:therapeutic use*; D017211:Treatment Failure; D014633:Valine; D000077484:Vemurafenib
chemical_list: D000970:Antineoplastic Agents; D007211:Indoles; D013449:Sulfonamides; D000077484:Vemurafenib; D018698:Glutamic Acid; C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf; D014633:Valine