title: Semduramicin in eggs--the incompatibility of feed and food maximum levels.
abstract: The cross-contamination of non-target feeds with coccidiostats may result in the occurrence of their residues in food of animal origin. To assure food safety, maximum levels (ML) of coccidiostats have been set for both feed and food. However, scientific data are not available on the transfer of some coccidiostats from feed into food. This experiment was therefore designed to verify, whether the administration of compliant semduramicin-contaminated feed could cause the occurrence of volatile residues of coccidiostats in eggs. The laying hens received feed containing 0.27 ± 0.034 mg/kg of semduramicin (ML=0.25 mg/kg). Semduramicin residues were detected in whole eggs after two days of administration of semduramicin-containing diet. A plateau level was achieved (16.1 ± 5.19 μg/kg, mean ± SD) with the concentrations significantly exceeding the maximum level of semduramicin in eggs (2 μg/kg). The results of this experiment might be a signal for the revision of the ML value.
authors.affiliation: National Veterinary Research Institute, Department of Pharmacology and Toxicology, Al. Partyzantow 57, 24-100 Pulawy, Poland. Electronic address: malgorzata.olejnik@piwet.pulawy.pl.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Olejnik
authors.forename: Teresa
authors.initials: T
authors.lastname: Szprengier-Juszkiewicz
authors.forename: Piotr
authors.initials: P
authors.lastname: Jedziniak
mesh_terms: D000821:Animal Feed / Q000032:analysis*; D000818:Animals; D002645:Chickens; D003049:Coccidiostats / Q000032:analysis*; D004350:Drug Residues / Q000032:analysis*; D004531:Eggs / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis*; D009550:Nigericin / Q000031:analogs & derivatives* / Q000032:analysis
chemical_list: D003049:Coccidiostats; C072941:semduramicin; D009550:Nigericin
keywords: Coccidiostats; Eggs; Feed cross-contamination; Maximum level; Semduramicin