title: Determination of galantamine hydrobromide in bulk drug and pharmaceutical dosage form by spectrofluorimetry.
abstract: OBJECTIVE
  To develop a simple, accurate, sensitive, rapid and precise method for the determination of galantamine hydrobromide in bulk drug and pharmaceutical dosage form.
  
  
  METHODS
  The method employs wavelength detection and determination of galantamine hydrobromide at excitation wavelength 282 nm and emission wavelength 607 nm in a solution of simple distilled water.
  
  
  CONCLUSIONS
  The method was found to be linear in the range of 2-14 μg/ml having r (2) = 0.9999. The mean accuracy was found to be 98.12% to 99.67%. The intraday and interday precision was found to be 0.18-0.35% and 0.13-0.46%, respectively. The limit of detection was found to be 0.29 μg/ml. The limit of quantification was found to be 0.89 μg/ml. The method was successfully applied for the determination of galantamine hydrobromide in bulk drug as well as pharmaceutical dosage form.
authors.affiliation: Department of Quality Assurance, Shri Sarvajanik Pharmacy College, Near Aravind Baug, Mehsana, Gujarat, India.
authors.forename: Amit V
authors.initials: AV
authors.lastname: Patel
authors.forename: Vishal J
authors.initials: VJ
authors.lastname: Patel
authors.forename: Avani V
authors.initials: AV
authors.lastname: Patel
authors.forename: Jayant B
authors.initials: JB
authors.lastname: Dave
authors.forename: Chhaganbhai N
authors.initials: CN
authors.lastname: Patel
keywords: Galantamine hydrobromide; analytical assay method; spectrofluorimetry method