title: Remote chirality control based on the organocatalytic asymmetric Mannich reaction of α-thio acetaldehydes.
abstract: Remote chirality control leading to 1,4-difunctionalized compounds such as 1,4-amino alcohols and 1,4-diamines was achieved by both syn- and anti-selective asymmetric Mannich reactions of α-thio acetaldehydes, the subsequent olefination and the stereospecific 2,3-sigmatropic rearrangement.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan. maruoka@kuchem.kyoto-u.ac.jp.
authors.forename: Taichi
authors.initials: T
authors.lastname: Kano
authors.forename: Ryu
authors.initials: R
authors.lastname: Sakamoto
authors.forename: Keiji
authors.initials: K
authors.lastname: Maruoka