title: Palladium-catalyzed coupling of alkynes with unactivated alkenes in ionic liquids: a regio- and stereoselective synthesis of functionalized 1,6-dienes and their analogues.
abstract: A palladium-catalyzed regio- and stereoselective intermolecular tandem reaction of alkynes and unactivated 1,6-enols in ionic liquids is described, providing a practical, efficient, and versatile method for the synthesis of functionalized 1,6-dienes in moderate to good yields. The present reaction has high functional-group tolerance and gives products on a gram scale. Mechanistic studies indicate that the reaction might proceed via a chain-walking mechanism.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, P. R. China.
authors.forename: Jianxiao
authors.initials: J
authors.lastname: Li
authors.forename: Shaorong
authors.initials: S
authors.lastname: Yang
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.forename: Jinwu
authors.initials: J
authors.lastname: Zhao