title: Timed up and go, cognitive, and quality-of-life correlates in Parkinson's disease.
abstract: OBJECTIVE
  To examine the relationship between Timed Up and Go (TUG) performance, verbal executive function (EF) performance, and quality-of-life (QOL) measures in Parkinson's disease (PD).
  
  
  METHODS
  Cross-sectional.
  
  
  METHODS
  Sixteen movement disorder centers from across the United States.
  
  
  METHODS
  Patients with PD (N=1964).
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  TUG test, immediate and delayed 5-word recall, verbal fluency, PD QOL Questionnaire.
  
  
  RESULTS
  TUG performance and verbal EF performance were significantly associated with, and predictors of, QOL measures, having the greatest association and predictability with the mobility domain of the QOL measures.
  
  
  CONCLUSIONS
  The TUG test and verbal EF tests have QOL correlates, making the combined evaluation of mobility, cognitive, and QOL decline a potential examination tool to evaluate the sequelae of PD.
authors.affiliation: Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL; Department of Kinesiology, Iowa State University, Ames, IA.
authors.forename: Elizabeth L
authors.initials: EL
authors.lastname: Stegemöller
authors.affiliation: VA Rehabilitation R&D Center of Excellence, Atlanta VA Medical Center, Atlanta, GA; Department of Neurology, Emory University, Atlanta, GA.
authors.forename: Joe
authors.initials: J
authors.lastname: Nocera
authors.affiliation: Department of Neurology, Center for Movement Disorders & Neurorestoration, University of Florida, Gainesville, FL.
authors.forename: Irene
authors.initials: I
authors.lastname: Malaty
authors.affiliation: Departments of Statistics and Political Science, Iowa State University, Ames, IA.
authors.forename: Mack
authors.initials: M
authors.lastname: Shelley
authors.affiliation: Department of Neurology, Center for Movement Disorders & Neurorestoration, University of Florida, Gainesville, FL.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Okun
authors.affiliation: Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL. Electronic address: cjhass@hhp.ufl.edu.
authors.forename: Chris J
authors.initials: CJ
authors.lastname: Hass
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D004185:Disability Evaluation; D056344:Executive Function / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000502:physiology; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology* / Q000523:psychology*; D011788:Quality of Life; D012044:Regression Analysis; D011795:Surveys and Questionnaires; D014706:Verbal Learning / Q000502:physiology
keywords: Cognition; Parkinson's disease; Quality of life; Rehabilitation