title: Fungal infections associated with long-term mechanical circulatory support-diagnosis and management.
abstract: Left ventricular assist devices (LVADs) are increasingly used as a treatment option for advanced heart failure. Fungal infections present a serious concern given the high association with major adverse events including death in this group of patients. The objective of this review is to summarize the incidence, risk factors, method for diagnosis, complication rate, and outcomes in patients with VADs who develop fungal infections.
authors.affiliation: Department of Cardiovascular Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; Department of Cardiovascular Surgery, Second Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
authors.forename: Jiri
authors.initials: J
authors.lastname: Maly
authors.forename: Ondrej
authors.initials: O
authors.lastname: Szarszoi
authors.forename: Ivan
authors.initials: I
authors.lastname: Netuka
authors.forename: Zora
authors.initials: Z
authors.lastname: Dorazilova
authors.forename: Jan
authors.initials: J
authors.lastname: Pirk
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage; D001228:Aspergillosis; D002177:Candidiasis; D015725:Fluconazole / Q000008:administration & dosage; D006333:Heart Failure / Q000628:therapy; D006353:Heart-Assist Devices / Q000009:adverse effects* / Q000382:microbiology*; D006801:Humans; D015994:Incidence; D009181:Mycoses / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D011743:Pyrimidines / Q000008:administration & dosage; D012307:Risk Factors; D013997:Time Factors; D014230:Triazoles / Q000008:administration & dosage; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D015725:Fluconazole; D065819:Voriconazole