title: A parametric finite element analysis of the compacted bone-cement interface following balloon kyphoplasty.
abstract: Treating fractures of the spine is a major challenge for the medical community with an estimated 1.4 million fractures per annum worldwide. While a considerable volume of study exists on the biomechanical implications of balloon kyphoplasty, which is used to treat these fractures, the influence of the compacted bone-cement region properties on stress distribution within the vertebral body remains unknown. The following article describes a novel method for modelling this compacted bone-cement region using a geometry-based approach in conjunction with the knowledge of the bone volume fractions for the native and compacted bone regions. Three variables for the compacted region were examined, as follows: (1) compacted thickness, (2) compacted region Young's modulus and (3) friction coefficient. Results from the model indicate that the properties of the compacted bone-cement region can affect stresses in the cortical bone and cement by up to +28% and -40%, respectively. These findings demonstrate the need for further investigation into the effects of the compacted bone-cement interface using computational and experimental methods on multi-segment models.
authors.affiliation: Bioengineering Technology Centre, Institute of Technology Tallaght, Dublin, Ireland.
authors.forename: Philip
authors.initials: P
authors.lastname: Purcell
authors.forename: Magdalena
authors.initials: M
authors.lastname: Tyndyk
authors.forename: Fiona
authors.initials: F
authors.lastname: McEvoy
authors.forename: Stephen
authors.initials: S
authors.lastname: Tiernan
authors.forename: Seamus
authors.initials: S
authors.lastname: Morris
mesh_terms: D001696:Biomechanical Phenomena / Q000502:physiology; D001843:Bone Cements / Q000737:chemistry*; D055119:Elastic Modulus; D020342:Finite Element Analysis; D006801:Humans; D058498:Kyphoplasty; D008954:Models, Biological; D015233:Models, Statistical; D013131:Spine / Q000737:chemistry / Q000502:physiology* / Q000601:surgery*
chemical_list: D001843:Bone Cements
keywords: Kyphoplasty; biomechanics; bone–cement interface; parametric finite element analysis; vertebral augmentation