title: [Development of Chinese forensic Y-STR DNA database].
abstract: Y chromosome is a male-specific paternal inherited chromosome. The STR markers on Y chromosome have been widely used in forensic practices. This article summarizes the characteristics of Y-STR and some factors are considered of selecting appropriate Y-STR markers for Chinese population. The prospects of existing and potential forensic applications of Y-STR profiles are discussed including familial excluding, familial searching, crowd source deducing, mixture sample testing, and kinship identifying. The research, development, verification of Y-STR kit, Y-STR mutation rate, and search software are explored and some suggestions are given.
authors.affiliation: Health Science Center, University of North Texas, Texas 76107, USA. Jianye.Ge@unthsc.edu
authors.forename: Jian-Ye
authors.initials: JY
authors.lastname: Ge
authors.forename: Jiang-Wei
authors.initials: JW
authors.lastname: Yan
authors.forename: Qun
authors.initials: Q
authors.lastname: Xie
authors.forename: Hong-Yu
authors.initials: HY
authors.lastname: Sun
authors.forename: Huai-Gu
authors.initials: HG
authors.lastname: Zhou
authors.forename: Bin
authors.initials: B
authors.lastname: Li
mesh_terms: D044466:Asian People / Q000235:genetics*; D041322:Chromosomes, Human, Y; D004247:DNA / Q000032:analysis / Q000235:genetics; D016172:DNA Fingerprinting; D030561:Databases, Nucleic Acid; D005260:Female; D005554:Forensic Medicine / Q000379:methods*; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats; D009154:Mutation; D016133:Polymerase Chain Reaction; D011933:Reagent Kits, Diagnostic; D012984:Software
chemical_list: D011933:Reagent Kits, Diagnostic; D004247:DNA