title: Synthesis and antioxidant activity of styrylsulfonylmethyl 1,3,4-oxadiazoles, pyrazolyl/isoxazolyl-1,3,4-oxadiazoles.
abstract: A new class of mono and bis heterocycles-styrylsulfonylmethyl 1,3,4-oxadiazoles, pyrazolyl/isoxazolyl-1,3,4-oxadiazoles were prepared and studied their antioxidant activity. The compound methyl substituted 2-(p-methylphenylamino-sulfonylmethyl)-5-[Z-(p-methylstyrylsulfonylmethyl)]-1,3,4-oxadiazole displayed slightly higher antioxidant activity than the standard ascorbic acid.
authors.affiliation: Department of Chemistry, Sri Venkateswara University.
authors.forename: Guda
authors.initials: G
authors.lastname: Mallikarjuna Reddy
authors.forename: Akkarapalli
authors.initials: A
authors.lastname: Muralikrishna
authors.forename: Venkatapuram
authors.initials: V
authors.lastname: Padmavathi
authors.forename: Adivireddy
authors.initials: A
authors.lastname: Padmaja
authors.forename: Thandaiah
authors.initials: T
authors.lastname: Krishna Tilak
authors.forename: Chippada
authors.initials: C
authors.lastname: Appa Rao
mesh_terms: D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000737:chemistry; D006861:Hydrogen Peroxide / Q000737:chemistry; D008745:Methylation; D009569:Nitric Oxide / Q000737:chemistry; D010069:Oxadiazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D010851:Picrates / Q000737:chemistry; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D013450:Sulfones / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D010069:Oxadiazoles; D010851:Picrates; D011720:Pyrazoles; D013450:Sulfones; D009569:Nitric Oxide; C031280:pyrazole; D006861:Hydrogen Peroxide; C004931:1,1-diphenyl-2-picrylhydrazyl