title: What stories can the Frankia genomes start to tell us?
abstract: Among the Actinobacteria, the genus Frankia is well known for its facultative lifestyle as a plant symbiont of dicotyledonous plants and as a free-living soil dweller. Frankia sp. strains are generally classified into one of four major phylogenetic groups that have distinctive plant host ranges. Our understanding of these bacteria has been greatly facilitated by the availability of the first three complete genome sequences, which suggested a correlation between genome size and plant host range. Since that first report, eight more Frankia genomes have been sequenced. Representatives from all four lineages have been sequenced to provide vital baseline information for genomic approaches toward understanding these novel bacteria. An overview of the Frankia genomes will be presented to stimulate discussion on the potential of these organisms and a greater understanding of their physiology and evolution.
authors.affiliation: Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, USA.
authors.forename: Louis S
authors.initials: LS
authors.lastname: Tisa
authors.forename: Nicholas
authors.initials: N
authors.lastname: Beauchemin
authors.forename: Maher
authors.initials: M
authors.lastname: Gtari
authors.forename: Arnab
authors.initials: A
authors.lastname: Sen
authors.forename: Luis G
authors.initials: LG
authors.lastname: Wall
mesh_terms: D040161:Frankia / Q000145:classification / Q000235:genetics*; D005798:Genes, Bacterial; D059646:Genome Size; D016680:Genome, Bacterial; D059014:High-Throughput Nucleotide Sequencing; D005810:Multigene Family; D009586:Nitrogen Fixation / Q000502:physiology; D010944:Plants / Q000382:microbiology; D012045:Regulatory Sequences, Nucleic Acid; D053204:Root Nodules, Plant / Q000382:microbiology / Q000502:physiology; D017422:Sequence Analysis, DNA; D013045:Species Specificity; D013559:Symbiosis