title: Experimental reproduction of stages of the respiratory distress syndrome.
abstract: The authors present a method for experimental reproduction of stages of the acute respiratory distress syndrome development, including the initial stage - acute pulmonary injury. Concentrated neutrophil transmitters served as the factor triggering the development of the process. The adequacy of the model was confirmed by the clear-cut morphological stages of the process. The possibility of reproducing the syndrome by injection of concentrated neutrophil transmitters confirmed their leading role in impairment of the alveolar capillary membrane.
authors.affiliation: Chita State Medical Academy, Russia. lenap75@mail.ru.
authors.forename: E V
authors.initials: EV
authors.lastname: Prutkina
authors.forename: A V
authors.initials: AV
authors.lastname: Sepp
authors.forename: N N
authors.initials: NN
authors.lastname: Tsybikov
authors.forename: N V
authors.initials: NV
authors.lastname: Isakova
mesh_terms: D000818:Animals; D021461:Animals, Outbred Strains; D002457:Cell Extracts; D004195:Disease Models, Animal; D006801:Humans; D008168:Lung / Q000098:blood supply / Q000473:pathology; D008297:Male; D009504:Neutrophils / Q000502:physiology; D051381:Rats; D012128:Respiratory Distress Syndrome / Q000139:chemically induced / Q000473:pathology*
chemical_list: D002457:Cell Extracts