title: Metastatic ovarian tumors: a clinicopathologic study of 150 cases.
abstract: OBJECTIVE
  To determine the frequency of metastatic ovarian tumors and to identify their clinicopathologic features.
  
  
  METHODS
  A total of 150 patients with pathologically confirmed metastatic ovarian carcinoma who were treated between 1995 and 2011 at the Mexican Oncology Hospital were identified by retrospective review. Clinicopathologic data were analyzed.
  
  
  RESULTS
  Metastatic ovarian carcinoma accounted for 15.7% of all ovarian malignancies. The primary sites of nongynecologic tumors were the colon (30%), stomach (16%), appendix (13%), breast (13%), pancreas (12%), biliary tract (15%), and liver (4%). Gynecologic primary sites were the uterine cervix (4%) and the uterine body (23%). Primary malignancies were detected first in 66 patients (44%) and simultaneously with ovarian metastasis in 53 patients (35.3%). An ovarian mass was the first manifestation of disease in 20.6% of the cases. The patients ranged in age from 26 to 72 years (mean, 51). Krukenberg tumors were found in 35 patients (23%). The cut surfaces of the ovaries were solid in 68 patients, solid-cystic in 38, and multicystic in 44.
  
  
  CONCLUSIONS
  Metastatic ovarian carcinomas are an important group of ovarian neoplasms, constituting 15.7% of all ovarian malignancies. Most of them arise from the gastrointestinal tract.
authors.affiliation: Department of Pathology, Mexican Oncology Hospital, Mexico, D.F., Mexico. keme2.tijax12@gmail.com
authors.forename: Isabel
authors.initials: I
authors.lastname: Alvarado-Cabrero
authors.forename: Adriana
authors.initials: A
authors.lastname: Rodríguez-Gómez
authors.forename: Jorge
authors.initials: J
authors.lastname: Castelan-Pedraza
authors.forename: Raquel
authors.initials: R
authors.lastname: Valencia-Cedillo
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000556:secondary*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*