title: Regression of follicular lymphoma of the duodenum following eradication of H. pylori infection.
abstract: A 64-year-old woman was referred for an examination of the upper gastrointestinal (GI) tract. Endoscopy showed an elevated lesion in the duodenum with central depression and multiple white granules. Biopsy specimens revealed lymphoid follicles composed predominantly of centrocytes with scattered centroblasts. The tumor cells were positive for bcl-2. The patient was diagnosed with follicular lymphoma and underwent antibiotic therapy for Helicobacter pylori (H. pylori) infection. The regression of the lesion was obvious. After 5.5 years of follow-up, there has been no evidence of recurrence. This case suggests that H. pylori eradication therapy is effective for treating follicular lymphoma in the duodenum.
authors.affiliation: Department of Internal Medicine, IHI Harima Hospital, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Hayashi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Onishi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mitsuoka
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ogura
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Maeda
authors.forename: Takashi
authors.initials: T
authors.lastname: Nishigami
authors.forename: Masaru
authors.initials: M
authors.lastname: Harada
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004379:Duodenal Neoplasms / Q000150:complications* / Q000473:pathology; D004381:Duodenal Ulcer / Q000150:complications / Q000188:drug therapy; D005260:Female; D016481:Helicobacter Infections / Q000150:complications* / Q000188:drug therapy; D016480:Helicobacter pylori; D006801:Humans; D008224:Lymphoma, Follicular / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D012074:Remission Induction
chemical_list: D000900:Anti-Bacterial Agents