title: Large current difference in Au-coated vertical silicon nanowire electrode array with functionalization of peptides.
abstract: Au-coated vertical silicon nanowire electrode array (VSNEA) was fabricated using a combination of bottom-up and top-down approaches by chemical vapor deposition and complementary metal-oxide-semiconductor process for biomolecule sensing. To verify the feasibility for the detection of biomolecules, Au-coated VSNEA was functionalized using peptides having a fluorescent probe. Cyclic voltammograms of the peptide-functionalized Au-coated VSNEA show a steady-state electrochemical current behavior. Because of the critically small dimension and vertically aligned nature of VSNEA, the current density of Au-coated VSNEA was dramatically higher than that of Au film electrodes. Au-coated VSNEA further showed a large current difference with and without peptides that was nine times more than that of Au film electrodes. These results indicate that Au-coated VSENA is highly effective device to detect peptides compared to conventional thin-film electrodes. Au-coated VSNEA can also be used as a divergent biosensor platform in many applications.
authors.affiliation: Department of Materials Science and Engineering, Yonsei University, Seoul 120-749, Republic of Korea. yblim@yonsei.ac.kr.
authors.forename: Ilsoo
authors.initials: I
authors.lastname: Kim
authors.forename: So-Eun
authors.initials: SE
authors.lastname: Kim
authors.forename: Sanghun
authors.initials: S
authors.lastname: Han
authors.forename: Hyungsuk
authors.initials: H
authors.lastname: Kim
authors.forename: Jaehyung
authors.initials: J
authors.lastname: Lee
authors.forename: Du-Won
authors.initials: DW
authors.lastname: Jeong
authors.forename: Ju-Jin
authors.initials: JJ
authors.lastname: Kim
authors.forename: Yong-Beom
authors.initials: YB
authors.lastname: Lim
authors.forename: Heon-Jin
authors.initials: HJ
authors.lastname: Choi