title: Steroid nanocrystals prepared using the nano spray dryer B-90.
abstract: The Nano Spray Dryer B-90 offers a new, simple, and alternative approach for the production of drug nanocrystals. In this study, the preparation of steroid nanocrystals using the Nano Spray Dryer B-90 was demonstrated. The particle size was controlled by selecting the mesh aperture size. Submicrometer steroid particles in powder form were successfully obtained. These nanoparticles were confirmed to have a crystal structure using powder X-ray diffraction pattern analysis. Since drug nanocrystals have recently been considered as a novel type of drug formulation for drug delivery systems, this study will be useful for nano-medical applications.
authors.affiliation: Department of Ophthalmology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. koichi.baba@ophthal.med.osaka-u.ac.jp.
authors.forename: Koichi
authors.initials: K
authors.lastname: Baba
authors.forename: Kohji
authors.initials: K
authors.lastname: Nishida