title: Reduction of gastric cancer mortality by endoscopic and radiographic screening in an isolated island: A retrospective cohort study.
abstract: OBJECTIVE
  To evaluate the efficacy of endoscopic and radiographic screening for gastric cancer.
  
  
  METHODS
  A retrospective cohort study.
  
  
  METHODS
  Community in an isolated island.
  
  
  METHODS
  The study involved 186 patients (131 men, 55 women) diagnosed with gastric cancer between 2000 and 2005.
  
  
  METHODS
  Endoscopic and radiographic screening.
  
  
  METHODS
  The odds ratio of death from gastric cancer in participants versus non-participants of screening, the cumulative survival rate of the gastric cancer patients.
  
  
  RESULTS
  The odds ratio of death from gastric cancer in the participants versus non-participants of screening was 0.091 (95% confidence interval (CI) 0.027-0.308; P < 0.0001). The cumulative survival rate of the gastric cancer patients in the screening group was higher than that in the non-screening group (P < 0.0001). In the endoscopic screening district, the odds ratio of death from gastric cancer among the participants versus non-participants of endoscopic screening was 0.117 (95% CI 0.013-1.056; P = 0.0525), while in the radiographic screening district, it was 0.086 (95% CI 0.020-0.376; P < 0.0001). The cumulative survival rates were higher in both the screening groups as compared with the non-screening group (endoscopy, P = 0.0302; radiography, P = 0.0012).
  
  
  CONCLUSIONS
  The results suggest that both radiographic and endoscopic screening may prevent gastric cancer deaths.
authors.affiliation: Department of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
authors.forename: Satohiro
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Shizukiyo
authors.initials: S
authors.lastname: Ishikawa
authors.forename: Yukio
authors.initials: Y
authors.lastname: Yoshida
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D055088:Early Detection of Cancer; D005260:Female; D005773:Gastroscopy; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D016017:Odds Ratio; D017063:Outcome Assessment, Health Care; D011859:Radiography; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000401:mortality*; D015996:Survival Rate
keywords: endoscopy; gastric cancer; mass screening; mortality; radiography