title: Factors associated with pulmonary recurrence after pulmonary metastasectomy for sarcomatous disease.
abstract: OBJECTIVE
  To analyze the factors associated with survival and pulmonary recurrence after complete metastasectomy for patients with sarcomatous disease.
  
  
  METHODS
  Among the 51 patients who underwent complete pulmonary metastasectomy at our hospital between January 2002 and November 2010, 30 (58.8 %) suffered pulmonary recurrence in an ipsilateral hemithorax. We analyzed the factors affecting survival and recurrence after complete metastasectomy.
  
  
  RESULTS
  The 51 patients who underwent pulmonary metastasectomy comprised 33 male and 18 female patients, with a median age of 22 years (range 11-61 years). The median survival was 24 months. Multivariate analysis revealed recurrence (p = 0.016) and the type of tumor (p = 0.024) as independent predictors of survival. Recurrence developed in 30 (58.8 %) patients. The risk of recurrence was higher in patients with a DFI <12 months and >1 metastasis resected during the initial metastasectomy.
  
  
  CONCLUSIONS
  Based on the findings of our analysis, patients with a DFI <12 months and >1 metastases resected during initial surgery have a higher risk of recurrence. We recommend postoperative follow-up at frequent intervals and reconsideration of oncological treatment after complete resection.
authors.affiliation: Department of Thoracic Surgery, Istanbul Medical School, Istanbul University, Bentler sitesi A4/14, Goktürk, Istanbul, Turkey, drstanju@hotmail.com.
authors.forename: Serhan
authors.initials: S
authors.lastname: Tanju
authors.forename: Murat
authors.initials: M
authors.lastname: Saricam
authors.forename: Erkan
authors.initials: E
authors.lastname: Kaba
authors.forename: Murat
authors.initials: M
authors.lastname: Kapdagli
authors.forename: Sukru
authors.initials: S
authors.lastname: Dilege
authors.forename: Alper
authors.initials: A
authors.lastname: Toker
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local; D011013:Pneumonectomy; D012306:Risk; D012509:Sarcoma / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D015996:Survival Rate; D013997:Time Factors; D055815:Young Adult