title: Neonatal lupus erythematosis: a five-year case review.
abstract: Neonatal lupus erythematosus is an infrequent disease seen in newborns. It is caused by transplacental maternal autoantibody passage. Cutaneous involvement and congenital heart block (CHB) are the most common affections, although it may involve multiple organs like the liver, lungs, blood, nervous or digestive systems. This article present a review of the four cases diagnosed in the past five years in a Neonatal Unit, which shows the different clinical spectrum which can develop around this disease (CHB, multisystemic affection and two cutaneous cases), different autoantibodies (specially anti-SSA) with an early negativization during the first year of life and the possibility of future collagen vascular disease as occurred in one case.
authors.affiliation: Área de Pediatría, Hospital Costa del Sol, Marbella, Málaga, España. Electronic address: rocio.porcel.86@gmail.com.
authors.forename: Rocío
authors.initials: R
authors.lastname: Porcel Chacón
authors.affiliation: Área de Pediatría, Hospital Costa del Sol, Marbella, Málaga, España.
authors.forename: Leopoldo
authors.initials: L
authors.lastname: Tapia Ceballos
authors.affiliation: Área de Pediatría, Hospital Costa del Sol, Marbella, Málaga, España.
authors.forename: Rocío
authors.initials: R
authors.lastname: Díaz Cabrera
authors.affiliation: Área de Pediatría, Hospital Costa del Sol, Marbella, Málaga, España.
authors.forename: María Teresa
authors.initials: MT
authors.lastname: Gutiérrez Perandones
mesh_terms: D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008180:Lupus Erythematosus, Systemic / Q000151:congenital* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D013997:Time Factors
keywords: Afectación multisistémica; Autoantibodies; Autoanticuerpos; Bloqueo cardíaco congénito; Congenital heart block; Erythematosus; Lupus eritematoso neonatal; Multisystem involvement; Neonatal lupus