title: The role and regulation of secretion of erythropoietin in pregnancy.
abstract: Although erythropoietin plays a significant role in human metabolism, relatively little attention has been devoted in scientific literature to its role and mechanisms regulating its secretion in pregnancy. The authors of this article discussed the following issues: - construction, biological role and regulation of erythropoietin secretion, - its extra-hematologic effect, - erythropoietin concentration in normal and complicated pregnancy, - erythropoietin secretion in placenta, including its effect on placental function, - the role of erythropoietin in evaluation of fetal well-being. What seems to be a particularly promising trend in further studies is popularizing the measurement of EPO concentration in cord blood or amniotic fluid as fetal hypoxia marker.
authors.affiliation: Klinika Położnictwa i Ginekologii, Instytut Matki i Dziecka, Kasprzaka 17a, 01-211 Warszawa, 0048 22 32-77-044, anewak@gmail.com.
authors.forename: Aneta
authors.initials: A
authors.lastname: Kowalska-Kańka
authors.forename: Tomasz
authors.initials: T
authors.lastname: Maciejewski
authors.forename: Krzysztof Tomasz
authors.initials: KT
authors.lastname: Niemiec
mesh_terms: D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry; D015415:Biomarkers / Q000097:blood; D004921:Erythropoietin / Q000097:blood / Q000378:metabolism*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005311:Fetal Hypoxia / Q000097:blood* / Q000175:diagnosis*; D006801:Humans; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D004921:Erythropoietin