title: Lipid signalling in health and disease.
abstract: This series of reviews is based on the FEBS Advanced Course on 'Lipid Signaling and Cancer' (4-10 October 2012, Vico Equense, Italy). The course encompassed the relationships between studies of basic and more translational aspects on the prevalence of altered lipid metabolism in different cancer types with a particular focus on phosphoinositides and sphingolipids. The reviews highlight both the basic aspects of these lipid classes and their roles in cancer development, and their potential as drug targets in cancer treatment.
authors.affiliation: Institute of Protein Biochemistry, National Research Council, Naples, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Corda
authors.forename: Maria Antonietta
authors.initials: MA
authors.lastname: De Matteis
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D006801:Humans; D050356:Lipid Metabolism / Q000187:drug effects*; D009369:Neoplasms / Q000188:drug therapy* / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects*
chemical_list: D000970:Antineoplastic Agents