title: Epidemiology of skin cancer: role of some environmental factors.
abstract: The incidence rate of melanoma and non-melanoma skin cancer entities is dramatically increasing worldwide. Exposure to UVB radiation is known to induce basal and squamous cell skin cancer in a dose-dependent way and the depletion of stratospheric ozone has implications for increases in biologically damaging solar UVB radiation reaching the earth's surface. In humans, arsenic is known to cause cancer of the skin, as well as cancer of the lung, bladder, liver, and kidney. Exposure to high levels of arsenic in drinking water has been recognized in some regions of the world. SCC and BCC (squamous and basal cell carcinoma) have been reported to be associated with ingestion of arsenic alone or in combination with other risk factors. The impact of changes in ambient temperature will influence people's behavior and the time they spend outdoors. Higher temperatures accompanying climate change may lead, among many other effects, to increasing incidence of skin cancer.
authors.affiliation: Department of Systematic Pathology, Division of Dermatology, University of Naples Federico II, Naples, Italy. gafabbro@unina.it.
authors.forename: Gabriella
authors.initials: G
authors.lastname: Fabbrocini
authors.forename: Maria
authors.initials: M
authors.lastname: Triassi
authors.forename: Maria Chiara
authors.initials: MC
authors.lastname: Mauriello
authors.forename: Guglielma
authors.initials: G
authors.lastname: Torre
authors.forename: Maria Carmela
authors.initials: MC
authors.lastname: Annunziata
authors.forename: Valerio
authors.initials: V
authors.lastname: De Vita
authors.forename: Francesco
authors.initials: F
authors.lastname: Pastore
authors.forename: Vincenza
authors.initials: V
authors.lastname: D'Arco
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Monfrecola