title: [Long-term outcomes of ileal pouch-anal canal anastomosis in children with ulcerative colitis].
abstract: The present study investigated the long-term outcomes of restorative proctocolectomy in pediatric patients with ulcerative colitis (UC). We report a series of 25 patients who underwent total proctocolectomy with ileal pouch-anal canal anastomosis (IACA). Surgery was performed for medically intractable colitis and severe colitis in 14 and 11 patients, respectively. Early and late complications were observed in 6 (24%) and 14 (56%) patients, respectively. The long-term quality of life outcomes were satisfactory, including both bowel function and social function. Growth retardation was observed in 6 patients. Five patients exhibited catch-up growth and 3 patients overcame growth retardation. Patients with growth retardation tended to have a younger onset and longer duration of UC, as well as a longer duration and higher total dose of steroid use. In conclusion, the long-term outcomes of pediatric patients with UC undergoing IACA are satisfactory. Furthermore, to minimize the risk of growth retardation, surgery should be performed without delay.
authors.affiliation: Department of Surgery, Yokohama Municipal Citizen's Hospital.
authors.forename: Kenji
authors.initials: K
authors.lastname: Tatsumi
authors.forename: Akira
authors.initials: A
authors.lastname: Sugita
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Koganei
authors.forename: Ryo
authors.initials: R
authors.lastname: Futatsuki
authors.forename: Hirosuke
authors.initials: H
authors.lastname: Kuroki
authors.forename: Kyoko
authors.initials: K
authors.lastname: Yamada
authors.forename: Sayumi
authors.initials: S
authors.lastname: Nakao
authors.forename: Minako
authors.initials: M
authors.lastname: Sako
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kimura
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Arai
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Fukushima
mesh_terms: D000293:Adolescent; D001003:Anal Canal / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D003093:Colitis, Ulcerative / Q000150:complications / Q000601:surgery*; D039021:Colonic Pouches; D005260:Female; D005500:Follow-Up Studies; D006130:Growth Disorders / Q000209:etiology; D006801:Humans; D008297:Male; D016737:Proctocolectomy, Restorative; D011788:Quality of Life; D016896:Treatment Outcome