title: Peripheral iron metabolism in patients with focal cerebral ischemia.
abstract: To ascertain the possible role of iron as a risk factor for cerebral ischemia, we studied the serum levels of iron, transferrin and ferritin in 42 patients between the third and seventh days after a cerebral ischemic event (transient ischemic attack, reversible ischemic neurological deficit or cerebral infarction) and in 62 matched controls. The serum levels of iron did not differ significantly between cerebral ischemic patient and control groups. Serum transferrin levels were lower and ferritin higher in stroke patients than in controls. These values were not influenced by age, blood pressure, or smoking and alcohol drinking habits. These results suggest that iron stores could be related to the risk for cerebral ischemia.
authors.affiliation: Department of Neurology, Hospital Doce de Octubre, Madrid, SpainDepartment of Neurology, Universitario "Principe de Asturias", Alcalá de Henares, Doce de Octubre, Madrid, SpainDepartment of Neurology, Universitario San Carlos, Madrid, SpainDepartment of Biochemistry, Hospital Doce de Octubre, Madrid, SpainDepartment of Biochemistry, Ciudad Sanitaria La Paz, Madrid, Spain.
authors.forename: J A
authors.initials: JA
authors.lastname: Molina
authors.forename: F J
authors.initials: FJ
authors.lastname: Jiménez-Jiménez
authors.forename: L
authors.initials: L
authors.lastname: Ayuso-Peralta
authors.forename: F
authors.initials: F
authors.lastname: Cabrera-Valdivia
authors.forename: A
authors.initials: A
authors.lastname: Pérez-Sempere
authors.forename: J A
authors.initials: JA
authors.lastname: Egido
authors.forename: C
authors.initials: C
authors.lastname: Soriano-Soriano
authors.forename: M T
authors.initials: MT
authors.lastname: Gómez-Lzquierdo
authors.forename: M C
authors.initials: MC
authors.lastname: Muñoz-Rivero
authors.forename: P
authors.initials: P
authors.lastname: Fernández-Calle
keywords: Acute cerebral ischemia; Ferritin; Iron; Serum levels; Transferrin