title: Association between Low-level Mercury Exposure and Neurobehavioral Functions in Korean Adults Living in a Coastal City.
abstract: OBJECTIVE
  The aim of this study was to determine the association between low-level mercury exposure and neurobehavioral functions in adults living in coastal regions of Korea.
  
  
  METHODS
  We selected 172 adults aged 20-65 years living in a city in the coastal region of Korea. A sociodemographic survey was conducted, mercury levels in the blood, urine, and hair were measured, and the associations according to computerized neurobehavioral tests were determined using univariate analysis. After adjustment for associated variables, a multivariate linear regression analysis was performed.
  
  
  RESULTS
  The geometric mean mercury levels in the blood, urine, and hair were 5.41 µg/L (range, 0.00-15.84 µg/L), 1.17 µg/g-creatinine (range, 0.00-32.86 µg/g-creatinine), and 1.37 mg/kg (range, 0.42-6.56 mg/kg), respectively. Variables that were associated with simple reaction time according to the neurobehavioral test results were age and urine mercury level. Variables associated with choice reaction time were the recent use of Korean traditional medicine and urine mercury level. Variables associated with the right-hand finger tapping speed test were age, gender, smoking behavior, education level, monthly household income, and urine mercury level. Variables associated with the left-hand finger tapping speed test were age, gender, education level, and urine mercury level. After adjustment for associated variables, there was no significant association between urine mercury level and simple reaction time (β=25.96; p=0.47), choice reaction time (β=50.37; p=0.32), or the number of left-hand finger taps (β=-1.54; p=0.21). However, urine mercury level was significantly associated with the number of right-hand finger taps (β=-3.86; p=0.01).
  
  
  CONCLUSIONS
  We found no evidence that low-level mercury exposure in adults is associated with deficits in neurobehavioral functions. A longer follow-up study is required to confirm this conclusion.
authors.affiliation: Department of Preventive Medicine & Environmental Health Center, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Rock Bum
authors.initials: RB
authors.lastname: Kim
authors.forename: Byoung-Gwon
authors.initials: BG
authors.lastname: Kim
authors.forename: Yu-Mi
authors.initials: YM
authors.lastname: Kim
authors.forename: Young-Seoub
authors.initials: YS
authors.lastname: Hong
authors.forename: Chang-Hun
authors.initials: CH
authors.lastname: You
authors.forename: Dae-Seon
authors.initials: DS
authors.lastname: Kim
keywords: Adult; Coastal area; Mercury; Neurobehavioral function