title: Polyostotic Paget's Disease with Sarcomatous Change in a Skull Lesion. A Case Report of Imaging Findings.
abstract: The most serious complication of Paget's disease is sarcomatous degeneration of pagetic bone. Multifocal sarcomatous degeneration occurs mainly in polyostotic Paget's disease. Paget sarcomas are the most threatening sarcomas of bone irrespective of the histopathology, their prognosis being far more negative than primary sarcomas. Paget's disease is a common entity but osteosarcoma arising in Paget's disease is an infrequent complication. The skull involvement is even rarer. We report a case of malignant transformation of a skull lesion in a patient of polyostotic Paget's disease. Skull radiographs, computed tomography and magnetic resonance imaging scans of the tumour area show interesting results.
authors.affiliation: K G S Scans, Anna Nagar; Maduri, India - kgsscans@rediffmail.com.
authors.forename: K G
authors.initials: KG
authors.lastname: Srinivasan
authors.forename: A
authors.initials: A
authors.lastname: Gaikwad
authors.forename: K P
authors.initials: KP
authors.lastname: Ushanandhini
authors.forename: K
authors.initials: K
authors.lastname: Ritesh