title: Prognosis and follow-up of 135 patients with ischemic colitis over a five-year period.
abstract: OBJECTIVE
  To study the prognosis (recurrence and mortality) of patients with ischemic colitis (IC).
  
  
  METHODS
  This study was conducted in four Spanish hospitals, participants in the Ischemic Colitis in Spain study We analyzed prospectively 135 consecutive patients who met criteria for definitive or probable IC according to Brandt criteria, and follow up these patients during the next five years, retrospectively. Long-term results (recurrence and mortality) were evaluated retrospectively after a median interval of 62 mo (range 54-75 mo).
  
  
  RESULTS
  Estimated IC recurrence rates were 2.9%, 5.1%, 8.1% and 9.7% at years 1, 2, 3 and 5 years, respectively. Five-year survival was 69% (93 of 135) and 24% (10 of 42 patients) died for causes related to the IC. Among these 10 patients, 8 died in their first episode at hospital (4 had gangrenous colitis and 4 fulminant colitis) and 2 due to recurrence.
  
  
  CONCLUSIONS
  The five-year recurrence rate of IC was low. On the other hand, mortality during follow-up was high and was not associated with ischemic colitis.
authors.affiliation: Angel Cosme, Nerea Borda, Luis Bujanda, Department of Gastroenterology, Hospital de Donostia-Instituto Biodonostia, Centro de Investigaciones Biomédicas en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Universidad del País Vasco UPV/EHU, 20014 San Sebastián, Spain.
authors.forename: Angel
authors.initials: A
authors.lastname: Cosme
authors.forename: Miguel
authors.initials: M
authors.lastname: Montoro
authors.forename: Santos
authors.initials: S
authors.lastname: Santolaria
authors.forename: Ana B
authors.initials: AB
authors.lastname: Sanchez-Puertolas
authors.forename: Marta
authors.initials: M
authors.lastname: Ponce
authors.forename: Margarita
authors.initials: M
authors.lastname: Durán
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Cabriada
authors.forename: Nerea
authors.initials: N
authors.lastname: Borda
authors.forename: Cristina
authors.initials: C
authors.lastname: Sarasqueta
authors.forename: Luis
authors.initials: L
authors.lastname: Bujanda
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017091:Colitis, Ischemic / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D013030:Spain; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
keywords: Colonic; Follow-up; Ischemic; Mortality; Recurrence