title: Successful treatment of suprasellar tumors associated with poor brain blood perfusion by severe intracranial arterial stenosis: two case reports.
abstract: BACKGROUND
  Treatment strategy to prevent perioperative cerebral infarction in patients with asymptomatic severe stenosis of the internal carotid artery is not fully established.
  
  
  METHODS
  Two patients were treated for skull base tumor in the presence of severe stenosis of the internal carotid artery, unilateral in one patient and bilateral in the other patient. Both patients were asymptomatic but had reduced vascular reserve capacity. The extended transsphenoidal approach was planned avoiding the low perfusion pressure region, with only conventional methods of maintaining blood pressure and PaCO2 rather than performing prophylactic vascular reconstruction surgery, and successful tumor removals were achieved without causing further neurological or radiological deficits.
  
  
  CONCLUSIONS
  If the surgical route is planned to avoid the distribution of stenotic vessels and low perfusion pressure, prophylactic vascular reconstruction surgery would be unnecessary. Although more experiences based on sub-classified etiology for internal carotid artery stenosis are required, various types of operations including intracranial-extracranial vascular surgery might be justified based on this principle.
authors.affiliation: Department of Neurosurgery, Kohnan Hospital, 4-20-1, Nagamachiminami, Taihaku-ku, Sendai, Miyagi 982-8523, Japan. yogawa@kohnan-sendai.or.jp.
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Ogawa
authors.forename: Teiji
authors.initials: T
authors.lastname: Tominaga
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D002560:Cerebrovascular Circulation; D003251:Constriction, Pathologic / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D055815:Young Adult