title: DMF as carbon source: Rh-catalyzed α-methylation of ketones.
abstract: An unprecedented Rh-catalyzed direct methylation of ketones with N,N-dimethylformamide (DMF) is disclosed. The reaction shows a broad substrate scope, tolerating both aryl and alkyl ketones with various substituents. Mechanistic studies suggest that DMF delivers a methylene fragment followed by a hydride in the methylation process.
authors.affiliation: Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education and School of Chemistry and Chemical Engineering, Shaanxi Normal University , Xi'an 710062, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Li
authors.forename: Dong
authors.initials: D
authors.lastname: Xue
authors.forename: Wei
authors.initials: W
authors.lastname: Lu
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
authors.forename: Zhao-Tie
authors.initials: ZT
authors.lastname: Liu
authors.forename: Jianliang
authors.initials: J
authors.lastname: Xiao