title: Graphene films show stable cell attachment and biocompatibility with electrogenic primary cardiac cells.
abstract: Graphene has attracted substantial attention due to its advantageous materialistic applicability. In the present study, we tested the biocompatibility of graphene films synthesized by chemical vapor deposition with electrogenic primary adult cardiac cells (cardiomyocytes) by measuring the cell properties such as cell attachment, survival, contractility and calcium transients. The results show that the graphene films showed stable cell attachment and excellent biocompatibility with the electrogenic cardiomyocytes, suggesting their useful applications for future cell biology studies.
authors.affiliation: School of Life Sciences and Systems Biology Research Center, Gwangju Institute of Science and Technology (GIST), Gwangju, 500-712, Korea.
authors.forename: Taeyong
authors.initials: T
authors.lastname: Kim
authors.forename: Yung Ho
authors.initials: YH
authors.lastname: Kahng
authors.forename: Takhee
authors.initials: T
authors.lastname: Lee
authors.forename: Kwanghee
authors.initials: K
authors.lastname: Lee
authors.forename: Do Han
authors.initials: DH
authors.lastname: Kim
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D002118:Calcium / Q000378:metabolism; D002448:Cell Adhesion; D002470:Cell Survival; D002478:Cells, Cultured; D006108:Graphite; D008297:Male; D009200:Myocardial Contraction; D032383:Myocytes, Cardiac / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D001672:Biocompatible Materials; D006108:Graphite; D002118:Calcium