title: Effect of community-based yoga intervention on oxidative stress and glycemic parameters in prediabetes: a randomized controlled trial.
abstract: OBJECTIVE
  To study the effectiveness of yoga intervention on oxidative stress, glycemic status, blood pressure and anthropometry in prediabetes.
  
  
  METHODS
  Randomized-controlled trial.
  
  
  METHODS
  Twenty nine prediabetes subjects aged 30-75 years.
  
  
  METHODS
  Yoga was conducted at 4 different community diabetes clinics in Mangalore, India.
  
  
  METHODS
  Participants were randomized to either 3-month yoga or wait-list control groups.
  
  
  METHODS
  Malondialdehyde, glutathione, vitamin C, vitamin E, superoxide dismutase, plasma glucose, glycated haemoglobin, BMI, waist circumference, waist-to-hip ratio and blood pressure.
  
  
  RESULTS
  Yoga intervention resulted in a significant decline in malondialdehyde (p<0.001), relative to the control group. In comparison with the control, there was a significant improvement in BMI, waist circumference, systolic blood pressure and fasting glucose levels at follow-up. No significant improvement in glycated haemoglobin, waist-to-hip ratio or any of the antioxidants was observed.
  
  
  CONCLUSIONS
  Yoga intervention may be helpful in control of oxidative stress in prediabetes subjects. Yoga can also be beneficial in reduction in BMI, waist circumference, systolic blood pressure and fasting glucose. Effect of yoga on antioxidant parameters was not evident in this study. The findings of this study need to be confirmed in larger trials involving active control groups.
authors.affiliation: Department of Biochemistry, Srinivas Institute of Medical Science and Research Centre, Mangalore, India. Electronic address: shreelaxmi.hegde@gmail.com.
authors.forename: Shreelaxmi V
authors.initials: SV
authors.lastname: Hegde
authors.forename: Prabha
authors.initials: P
authors.lastname: Adhikari
authors.forename: Sowmya
authors.initials: S
authors.lastname: Shetty
authors.forename: Poornima
authors.initials: P
authors.lastname: Manjrekar
authors.forename: Vivian
authors.initials: V
authors.lastname: D'Souza
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000975:Antioxidants / Q000378:metabolism; D001786:Blood Glucose / Q000378:metabolism*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress / Q000502:physiology*; D011236:Prediabetic State / Q000378:metabolism / Q000628:therapy*; D015013:Yoga
chemical_list: D000975:Antioxidants; D001786:Blood Glucose; D006442:Glycated Hemoglobin
keywords: Antioxidants; Glycated haemoglobin; Oxidative stress; Prediabetes; Yoga