title: pH-responsive micro- and nanocarrier systems.
abstract: Release on demand: The pH gradients between extra- and intracellular regions can be utilized for the controlled release of drugs and biological cargos from delivery systems. Biocompatible carrier systems with pH-cleavable units must fulfill many other criteria as well, for example, a long blood circulation time. This can be achieved by tailored micro- and nanocarriers based on macromolecular architectures or stable self-assembled systems.
authors.affiliation: Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195 Berlin (Germany) http://www.polytree.de.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Nowag
authors.forename: Rainer
authors.initials: R
authors.lastname: Haag
mesh_terms: D004337:Drug Carriers / Q000737:chemistry*; D016503:Drug Delivery Systems; D053758:Nanoparticles / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*
chemical_list: D004337:Drug Carriers; D011092:Polyethylene Glycols
keywords: drug delivery; macromolecular carrier systems; polyglycerols; polyphenols; self-assembly