title: Distal phalangeal necrosis in the extremities as a paraneoplastic syndrome in prostate cancer: an extremely rare case.
abstract: Paraneoplastic syndromes (PNSs) are rare disorders which are triggered by an altered immune system response to a neoplasm. Although prostate cancer (PCa) is the second most common urological malignancy associated with PNSs, literature is lacking in defining the cases representing different PNSs in PCa. Herein, we present a 50-year-old man with fulminant distal phalangeal necrosis in the lower extremities after a diagnosis of PCa. Additionally, we review the literature in light of this case.
authors.affiliation: Department of Urology, Erzincan University School of Medicine, Erzincan, Turkey.
authors.forename: Yigit
authors.initials: Y
authors.lastname: Akin
authors.forename: Selcuk
authors.initials: S
authors.lastname: Yucel
authors.forename: Mehmet
authors.initials: M
authors.lastname: Baykara
mesh_terms: D000671:Amputation, Surgical; D000726:Androgen Antagonists / Q000627:therapeutic use; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D018450:Disease Progression; D050278:Finger Phalanges / Q000473:pathology*; D005734:Gangrene; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D011471:Prostatic Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D050277:Toe Phalanges / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000726:Androgen Antagonists; D018931:Antineoplastic Agents, Hormonal