title: Total synthesis of sandresolide B and amphilectolide.
abstract: The total synthesis of the diterpenoids sandresolide B and amphilectolide from a common furan building block is presented. Key steps include palladium-mediated carbonylation, lanthanide catalyzed ring closure, Myers alkylation, intramolecular Friedel-Crafts acylation, photooxygenation, and a Kornblum-DeLaMare rearrangement.
authors.affiliation: Department of Chemistry and Center of Integrated Protein Science, University of Munich , Butenandtstrasse 5 - 13 (F4.086), 81377 Munich, Germany.
authors.forename: Ingrid T
authors.initials: IT
authors.lastname: Chen
authors.forename: Irina
authors.initials: I
authors.lastname: Baitinger
authors.forename: Lucas
authors.initials: L
authors.lastname: Schreyer
authors.forename: Dirk
authors.initials: D
authors.lastname: Trauner
mesh_terms: D004224:Diterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation
chemical_list: D004224:Diterpenes; C588096:amphilectolide; C588097:sandresolide B