title: Bacteremia due to Aeromonas hydrophila in acute lymphoblastic leukemia.
abstract: Aeromonas hydrophila (A. hydrophila) is a low virulent organism but may cause devastating fatal infections in immunocompromised host especially in liver cirrhosis. It is rarely reported to cause septicemia in a patient with Acute Lymphoblastic Leukemia (ALL). The mortality rate of septicemia due to A. hydrophila is 29% to 73%. We report a case of 59-year-old female patient who was a known case of ALL, presented with the complaints of fever, lethargy and generalized weakness for one month. After taking blood samples for investigations, empirical antimicrobial therapy was started. She did not improve after 48 hours of therapy. Meanwhile blood culture revealed pure growth of A. hydrophila. After sensitivity report was available, ciprofloxacin was started. Patient became afebrile after 48 hours of treatment with ciprofloxacin. It is very vital to correctly identified and treat bacteremia due to A. hydrophila especially in the underlying leukemic patient.
authors.affiliation: Department of Microbiology, Dr. Ziauddin University Hospital, North Nazimabad Campus, Karachi.
authors.forename: Ambreen
authors.initials: A
authors.lastname: Fatima
authors.forename: Faisal Iqbal
authors.initials: FI
authors.lastname: Afridi
authors.forename: Adnan
authors.initials: A
authors.lastname: Qureshi
authors.forename: Badar Jahan
authors.initials: BJ
authors.lastname: Farooqi
authors.forename: Arif
authors.initials: A
authors.lastname: Hussain
mesh_terms: D000208:Acute Disease; D016980:Aeromonas hydrophila / Q000302:isolation & purification / Q000472:pathogenicity*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy* / Q000209:etiology; D002939:Ciprofloxacin / Q000627:therapeutic use*; D005260:Female; D005334:Fever / Q000188:drug therapy / Q000209:etiology; D016905:Gram-Negative Bacterial Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D016867:Immunocompromised Host; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin