title: [Cervical pessary and prevention of preterm birth].
abstract: Cervical pessary is a promising tool to prevent preterm birth in high risk pregnant women with shortened midtrimester ultrasonographic cervical length. It is well tolerated by women. PECEP and ProTWIN trials have opened new fields of clinical research. Their results suggest that cervical pessary may prevent preterm birth in women with (i) singleton and cervical length ≤25 mm at 18-22weeks, and with (ii) twins and cervical length ≤37mm at 16-22weeks. These results must be confirmed by other randomized controlled trial before a generalization of cervical pessary in these situations. The role of cervical pessary in the existing strategies to prevent birth (progesterone, cerclage or combinations thereof) has to be determined.
authors.affiliation: Service de gynécologie-obstétrique, CHU d'Angers, 4, rue Larrey, 49033 Angers cedex 01, France. Electronic address: loicsentilhes@hotmail.com.
authors.forename: L
authors.initials: L
authors.lastname: Sentilhes
authors.affiliation: Service de gynécologie-obstétrique, CHU d'Angers, 4, rue Larrey, 49033 Angers cedex 01, France.
authors.forename: P
authors.initials: P
authors.lastname: Descamps
authors.affiliation: Service de gynécologie-obstétrique, CHU d'Angers, 4, rue Larrey, 49033 Angers cedex 01, France.
authors.forename: G
authors.initials: G
authors.lastname: Legendre
mesh_terms: D002584:Cervix Uteri / Q000000981:diagnostic imaging; D005260:Female; D005865:Gestational Age; D006801:Humans; D010570:Pessaries; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D059285:Pregnancy, Twin; D047928:Premature Birth / Q000517:prevention & control*; D011374:Progesterone / Q000008:administration & dosage; D014427:Twins; D016216:Ultrasonography, Prenatal; D002581:Uterine Cervical Incompetence / Q000628:therapy*
chemical_list: D011374:Progesterone
keywords: Cerclage; Cervical pessary; Pessaire; Prematurity; Prevention; Progesterone; Progestérone; Prématurité; Prévention