title: Stabilizing vitamin D(3) by conformationally selective co-crystallization.
abstract: A four-membered square-shaped H-bonding structure was successfully designed to synthesize vitamin D3 co-crystals. The co-crystallization process was found to be conformationally selective to result in topochemically stable materials.
authors.affiliation: Pharmaceutical Analytical & Solid-State Chemistry Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. xuefengmei@simm.ac.cn.
authors.forename: Jian-Rong
authors.initials: JR
authors.lastname: Wang
authors.forename: Chun
authors.initials: C
authors.lastname: Zhou
authors.forename: Xueping
authors.initials: X
authors.lastname: Yu
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Mei
mesh_terms: D002762:Cholecalciferol / Q000737:chemistry*; D003460:Crystallization; D004355:Drug Stability; D006860:Hydrogen Bonding; D008968:Molecular Conformation
chemical_list: D002762:Cholecalciferol