title: [Cumulative analgesic effects of EA stimulation of sanyinjiao (SP 6) in primary dysmenorrhea patients: a multicenter randomized controlled clinical trial].
abstract: OBJECTIVE
  To compare the cumulative analgesic effect of electroacupuncture (EA) stimulation of Sanyinjiao (SP 6), Xuanzhong (GB 39) and non-acupoint for primary dysmenorrhea patients.
  
  
  METHODS
  A total of 200 patients with primary dysmenorrhea were randomly assigned to Sanyinjiao (SP 6, a dysmenorrheal-relieving related acupoint) group, Xuanzhong (GB 39, an unrelated acupoint) group, non-acupoint group and control group, with 50 cases in each group. The participants were administered with EA (2 Hz/100 Hz, 0.5-1.6 mA) at SP 6, GB 39 and non-acupoint for 30 min, once daily for 3 consecutive days. The intensity of the pain was ranked from 0 (no pain) to 100 (intolerable) using visual analogue scale (VAS) and RSS (Cox retrospective symptom scale) severity rating scores (RSS-COX 2) before and after three interventions.
  
  
  RESULTS
  In comparison with the control group, VAS and RSS-COX 2 scores were significantly lower in the SP 36, GB 39 and non-acupoint groups (P < 0.001, P < 0.05), suggesting an alleviation of the pain severity after EA treatment. No significant differences were found among the three treatment groups in both VAS and RSS-COX 2 scores (P > 0.05).
  
  
  CONCLUSIONS
  EA stimulation of SP 6, GB 39 and non-acupoint has a good cumulative analgesic effect in patients with primary dysmenorrhea.
authors.affiliation: School of Acu-moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
authors.forename: Jia-Shan
authors.initials: JS
authors.lastname: Song
authors.forename: Yu-Qi
authors.initials: YQ
authors.lastname: Liu
authors.forename: Cun-Zhi
authors.initials: CZ
authors.lastname: Liu
authors.forename: Jie-Ping
authors.initials: JP
authors.lastname: Xie
authors.forename: Liang-Xiao
authors.initials: LX
authors.lastname: Ma
authors.forename: Lin-Peng
authors.initials: LP
authors.lastname: Wang
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Zheng
authors.forename: Zeng-Bin
authors.initials: ZB
authors.lastname: Ma
authors.forename: Huan
authors.initials: H
authors.lastname: Yang
authors.forename: Xu
authors.initials: X
authors.lastname: Chen
authors.forename: Guang-Xia
authors.initials: GX
authors.lastname: Shi
authors.forename: Shi-Liang
authors.initials: SL
authors.lastname: Li
authors.forename: Ji-Ping
authors.initials: JP
authors.lastname: Zhao
authors.forename: Jing-Xian
authors.initials: JX
authors.lastname: Han
authors.forename: Yan-Xia
authors.initials: YX
authors.lastname: Wang
authors.forename: Jian-Ping
authors.initials: JP
authors.lastname: Liu
authors.forename: Jiang
authors.initials: J
authors.lastname: Zhu
mesh_terms: D015667:Acupuncture Analgesia; D015669:Acupuncture Points; D000293:Adolescent; D000328:Adult; D000368:Aged; D004412:Dysmenorrhea / Q000628:therapy*; D015671:Electroacupuncture; D005260:Female; D006801:Humans; D010147:Pain Measurement; D055815:Young Adult