title: Norethindrone acetate in the medical management of adenomyosis.
abstract: The role of norethindrone acetate (NA) in the management of adenomyosis was evaluated with a retrospective chart review of 28 premenopausal women between 27-49 years of age presenting with moderate to severe pelvic pain and bleeding. Bleeding and dysmenorrhea scores were analyzed using paired T-tests. There was significant improvement of both dysmenorrhea and bleeding after treatment. Age showed no correlation with dysmenorrhea or bleeding. Low dose NA could be considered an effective, well-tolerated and inexpensive medical alternative to surgery for treating symptomatic adenomyosis. Large multicentric studies may help validate our findings.
authors.affiliation: Department of Obstetrics and Gynecology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA. ozgul.muneyyircidelale@downstate.edu.
authors.forename: Ozgul
authors.initials: O
authors.lastname: Muneyyirci-Delale
authors.forename: Ashadeep
authors.initials: A
authors.lastname: Chandrareddy
authors.forename: Siddhi
authors.initials: S
authors.lastname: Mankame
authors.forename: Nanna
authors.initials: N
authors.lastname: Osei-Tutu
authors.forename: Hans von
authors.initials: Hv
authors.lastname: Gizycki