title: Iridium-catalyzed asymmetric ring-opening reactions of azabenzonorbornadiene with carboxylic acid nucleophiles.
abstract: Iridium-catalyzed asymmetric ring-opening reaction of N-substituted azabenzonorbornadienes with various carboxylic acids has been developed. The ring-opening reaction offered trans-1,2-dihydronaphthalene products containing an allylic carboxylate moiety in moderate yields (up to 89 %) with high enantioselectivities (up to 96 %). The trans-configuration of the products was confirmed by X-ray crystallography.
authors.affiliation: School of Chemistry and Environment, South China Normal University, Guangzhou, 510006, China, yuhualong68@hotmail.com.
authors.forename: Yuhua
authors.initials: Y
authors.lastname: Long
authors.forename: Wenling
authors.initials: W
authors.lastname: Wang
authors.forename: Dingqiao
authors.initials: D
authors.lastname: Yang
authors.forename: Han
authors.initials: H
authors.lastname: Jiang
authors.forename: Kaixuan
authors.initials: K
authors.lastname: Chen
authors.forename: Yali
authors.initials: Y
authors.lastname: Fang
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D006575:Heterocyclic Compounds, 3-Ring / Q000737:chemistry*; D007495:Iridium / Q000737:chemistry*; D009636:Norbornanes / Q000737:chemistry*
chemical_list: D002264:Carboxylic Acids; D006575:Heterocyclic Compounds, 3-Ring; D009636:Norbornanes; D007495:Iridium