title: Intraosseous dentinogenic ghost cell tumor: a clinical report and literature update.
abstract: The dentinogenic ghost cell tumor (DGCT) is a relatively uncommon locally invasive neoplasm. This report describes the case of a 20-year-old Caucasian female patient who was diagnosed with an intraosseous DGCT in the left molar region of the mandible. Radiographic analysis revealed a well-circumscribed radiolucent lesion with focal radiopacity. Segmental resection of the mandible was performed by means of piezoelectric surgery. The histopathological examination yielded islands of odontogenic epithelium with clusters of ghost cells and dysplastic dentin, thus enabling the identification of the lesion as DGCT. Long-term surveillance of patients with intraosseous DGCTs is mandatory in order to detect in time any signs of recurrence. A literature update concerning intraosseous DGCTs is also provided.
authors.affiliation: Department of Oral and Maxillofacial Surgery, (Head: Prof. Dr. Dr. Rainer Schmelzeisen), Albert-Ludwigs University Hospital Freiburg, Germany.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Konstantakis
authors.affiliation: Specialist in Prosthodontics, Private Practice, Basel, Switzerland. Electronic address: panagiota.kosyfaki@yahoo.de.
authors.forename: Panagiota
authors.initials: P
authors.lastname: Kosyfaki
authors.affiliation: Oral Pathologist, Zentrum für Oralpathologie, Potsdam, Germany.
authors.forename: Harald
authors.initials: H
authors.lastname: Ebhardt
authors.affiliation: Department of Oral and Maxillofacial Surgery, (Head: Prof. Dr. Dr. Rainer Schmelzeisen), Albert-Ludwigs University Hospital Freiburg, Germany.
authors.forename: Rainer
authors.initials: R
authors.lastname: Schmelzeisen
authors.affiliation: Department of Oral and Maxillofacial Surgery, (Head: Prof. Dr. Dr. Rainer Schmelzeisen), Albert-Ludwigs University Hospital Freiburg, Germany.
authors.forename: Pit Jakob
authors.initials: PJ
authors.lastname: Voss
mesh_terms: D001860:Bone Plates; D054893:Cone-Beam Computed Tomography / Q000379:methods; D003804:Dentin / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008339:Mandibular Neoplasms / Q000175:diagnosis* / Q000601:surgery; D063175:Mandibular Reconstruction / Q000295:instrumentation; D009808:Odontogenic Tumors / Q000175:diagnosis* / Q000601:surgery; D059745:Piezosurgery / Q000379:methods; D011862:Radiography, Panoramic; D055815:Young Adult
keywords: Dentinogenic; Ghost cell; Intraosseous; Mandible; Resection; Tumor