title: Strong nucleosomes of A. thaliana concentrate in centromere regions.
abstract: Earlier identified strongest nucleosome DNA sequences of A. thaliana, those with visible 10-11 base sequence periodicity, are mapped along chromosomes. Resulting positional distributions reveal distinct maxima, one per chromosome, located in the centromere regions. Sequence-directed nucleosome mapping demonstrates that the strong nucleosomes (SNs) make tight arrays, several 'parallel' nucleosomes each, suggesting a columnar chromatin structure. The SNs represent a new class of centromeric nucleosomes, presumably, participating in synapsis of chromatids and securing the centromere architecture.
authors.affiliation: a Genome Diversity Center, Institute of Evolution, University of Haifa , Mount Carmel, Haifa 31905 , Israel.
authors.forename: Bilal
authors.initials: B
authors.lastname: Salih
authors.forename: Edward N
authors.initials: EN
authors.lastname: Trifonov
mesh_terms: D017360:Arabidopsis / Q000235:genetics*; D001483:Base Sequence; D002503:Centromere / Q000235:genetics*; D002874:Chromosome Mapping; D032461:Chromosomes, Plant / Q000235:genetics; D018744:DNA, Plant / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D009707:Nucleosomes / Q000235:genetics*; D017422:Sequence Analysis, DNA
chemical_list: D018744:DNA, Plant; D009707:Nucleosomes
keywords: MuDR; centromere; chromosome structure; helitron; strong nucleosome; transposable element