title: Use of lomustine (CCNU) in a case of cutaneous equine lymphoma.
abstract: A 12-year-old gelding was diagnosed with recurrent lymphoma in multiple cutaneous sites. A highly invasive preputial mass caused urethral obstruction. The horse was treated with surgery and chemotherapy consisting of lomustine (CCNU) and prednisolone. The treatment was well-tolerated and effective. This is the first reported use of lomustine (CCNU) in a horse for the treatment of equine lymphoma.
authors.affiliation: Department of Health Management (Doyle) and Department of Pathology and Microbiology (Bourque), Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 3P4, and Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (MacDonald).
authors.forename: Aimie J
authors.initials: AJ
authors.lastname: Doyle
authors.forename: Valerie S
authors.initials: VS
authors.lastname: MacDonald
authors.forename: Andrea
authors.initials: A
authors.lastname: Bourque
mesh_terms: D000818:Animals; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use*; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D052816:Foreskin / Q000601:surgery; D006734:Horse Diseases / Q000188:drug therapy* / Q000601:surgery; D006736:Horses; D008130:Lomustine / Q000627:therapeutic use*; D008223:Lymphoma / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D012878:Skin Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D014524:Urethral Obstruction / Q000209:etiology / Q000601:surgery / Q000662:veterinary
chemical_list: D018906:Antineoplastic Agents, Alkylating; D018931:Antineoplastic Agents, Hormonal; D008130:Lomustine; D011239:Prednisolone