title: Synthesis of a photocontrollable hydrogen sulfide donor using ketoprofenate photocages.
abstract: We report the design, synthesis and application of a directly photocontrollable hydrogen sulfide (H2S) donor, which releases H2S proportionally to the intensity and duration of photoirradiation. Photocontrolled H2S release from this donor was also demonstrated in bovine serum. This H2S donor should be suitable for use in various biological systems.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan. deco@phar.nagoya-cu.ac.jp.
authors.forename: Naoki
authors.initials: N
authors.lastname: Fukushima
authors.forename: Naoya
authors.initials: N
authors.lastname: Ieda
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Sasakura
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Nagano
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Hanaoka
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Suzuki
authors.forename: Naoki
authors.initials: N
authors.lastname: Miyata
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Nakagawa
mesh_terms: D000818:Animals; D001713:Biphenyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002417:Cattle; D006862:Hydrogen Sulfide / Q000097:blood / Q000737:chemistry*; D008027:Light; D008751:Methylene Blue / Q000737:chemistry; D010782:Photolysis; D013053:Spectrophotometry; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001713:Biphenyl Compounds; D013438:Sulfhydryl Compounds; D008751:Methylene Blue; D006862:Hydrogen Sulfide