title: Severe demodexfolliculorum-associated oculocutaneous rosacea in a girl successfully treated with ivermectin.
abstract: OBJECTIVE
  There is a limited therapeutic armamentarium for recalcitrant cases of childhood rosacea.
  
  
  METHODS
  We report the case of a 12-year-old girl who presented with severe ocular and cutaneous rosacea unresponsive to oral doxycycline, oral isotretinoin, and topical tacrolimus. A biopsy specimen showed numerous mites within the folliculosebaceous unit. Treatment with a single dose of oral ivermectin achieved resolution of her symptoms.
  
  
  CONCLUSIONS
  The causative role of Demodex folliculorum should be considered in immunocompetent children with rosacea or rosacea-like refractory eruptions. In such cases, treatment with ivermectin can be beneficial.
authors.affiliation: Department of Dermatology, School of Medicine, University of New Mexico, Albuquerque.
authors.forename: Megan
authors.initials: M
authors.lastname: Brown
authors.affiliation: Department of Dermatology, Hospital Infantil del Niño Jesús, Madrid, Spain.
authors.forename: Angela
authors.initials: A
authors.lastname: Hernández-Martín
authors.affiliation: Department of Ophthalmology, Hospital Infantil del Niño Jesús, Madrid, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Clement
authors.affiliation: Department of Pathology, Hospital Infantil del Niño Jesús, Madrid, Spain.
authors.forename: Isabel
authors.initials: I
authors.lastname: Colmenero
authors.affiliation: Department of Dermatology, Hospital Infantil del Niño Jesús, Madrid, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Torrelo
mesh_terms: D000818:Animals; D000977:Antiparasitic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002648:Child; D015822:Eye Infections, Parasitic / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D005260:Female; D006801:Humans; D007559:Ivermectin / Q000008:administration & dosage / Q000627:therapeutic use; D008924:Mite Infestations / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D012393:Rosacea / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D012720:Severity of Illness Index; D012876:Skin Diseases, Parasitic / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D016896:Treatment Outcome
chemical_list: D000977:Antiparasitic Agents; D007559:Ivermectin