title: SIRT7 an emerging sirtuin: deciphering newer roles.
abstract: Sirtuin7 (SIRT7) is a NAD(+)-dependent protein deacetylase which belongs to sirtuin family. Although sirtuin proteins have attracted a great deal of attention, little is known about SIRT7. SIRT7 participates in rDNA transcription in the nucleolus. However, recent reports show that SIRT7 has additional novel functions. This review summarizes all findings about SIRT7, and highlights its critical roles in cellular functions.
authors.affiliation: Department of Pharmacology and Department of Biomedical Science, School of Medicine, Kyung Hee University, Seoul, Republic of Korea. jekim@khu.ac.kr.
authors.forename: W
authors.initials: W
authors.lastname: Kim
authors.forename: J E
authors.initials: JE
authors.lastname: Kim
mesh_terms: D000818:Animals; D006655:Histone Deacetylases / Q000378:metabolism; D006801:Humans; D037761:Sirtuins / Q000235:genetics / Q000378:metabolism
chemical_list: C510661:SIRT7 protein, human; C539736:Sirt7 protein, mouse; D037761:Sirtuins; D006655:Histone Deacetylases