title: [Clinical value of CT-guided (125)I brachytherapy for retroperitoneal metastatic lymph node from PHC].
abstract: OBJECTIVE
  To discuss the clinical value of CT-guided (125)I brachytherapy with retroperitoneal metastatic lymph nodes from primary hepatic carcinoma(PHC).
  
  
  METHODS
  Twenty patients with retroperitoneal metastatic lymph node recurrence from PHC were percutaneously treated by (125)I brachytherapy with computed tomographic (CT) guidance. The number, radioactive dose, placed position of radioactive seeds and puncture path were determined by computerized treatment planning system (TPS). The radioactive seeds were implanted when the needles were in right position by CT scan. Radiotherapy verification and quality assessment were performed after treatment by CT scan. Follow-up contrast material-enhanced CT were reviewed.
  
  
  RESULTS
  The local control rate of 3, 6, 10, 15 months was 70.0%, 56.3%, 44.4%, 25.0% respectively. There were no severe complications such as massive bleeding and radiation injury of normal tissues.
  
  
  CONCLUSIONS
  CT-guided (125)I brachytherapy are effective and may be safely applied to retroperitoneal metastatic lymph nodes from PHC.
authors.affiliation: State Key Laboratory of Oncology in Southern China, Minimally Invasive and Interventional Department, Sun Yat-sen University Cancer Center,Guangzhou 510060, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Gao
authors.forename: Yang-kui
authors.initials: YK
authors.lastname: Gu
authors.forename: Jin-hua
authors.initials: JH
authors.lastname: Huang
authors.forename: Fu-jun
authors.initials: FJ
authors.lastname: Zhang
authors.forename: Pei-hong
authors.initials: PH
authors.lastname: Wu
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D012187:Retroperitoneal Space; D014057:Tomography, X-Ray Computed