title: Polyacrylic acid@zeolitic imidazolate framework-8 nanoparticles with ultrahigh drug loading capability for pH-sensitive drug release.
abstract: The polyacrylic acid@zeolitic imidazolate framework-8 (PAA@ZIF-8) nanoparticles (NPs) were first fabricated using a facile and simple route. It is worthwhile noting that the as-fabricated PAA@ZIF-8 NPs possessed ultrahigh doxorubicin (DOX) loading capability (1.9 g DOX g(-1) NPs), which were employed as pH-dependent drug delivery vehicles.
authors.affiliation: Faculty of Chemistry, Northeast Normal University, Changchun 130024, P. R. China. wangcg925@nenu.edu.cn zmsu@nenu.edu.cn.
authors.forename: Hong
authors.initials: H
authors.lastname: Ren
authors.forename: Lingyu
authors.initials: L
authors.lastname: Zhang
authors.forename: Jiping
authors.initials: J
authors.lastname: An
authors.forename: Tingting
authors.initials: T
authors.lastname: Wang
authors.forename: Lu
authors.initials: L
authors.lastname: Li
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Si
authors.forename: Liu
authors.initials: L
authors.lastname: He
authors.forename: Xiaotong
authors.initials: X
authors.lastname: Wu
authors.forename: Chungang
authors.initials: C
authors.lastname: Wang
authors.forename: Zhongmin
authors.initials: Z
authors.lastname: Su
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects; D004317:Doxorubicin / Q000737:chemistry* / Q000494:pharmacology; D004337:Drug Carriers / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles / Q000737:chemistry; D061986:MCF-7 Cells; D018613:Microscopy, Confocal; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D055672:Static Electricity; D017641:Zeolites / Q000737:chemistry
chemical_list: D000180:Acrylic Resins; D004337:Drug Carriers; D007093:Imidazoles; D017641:Zeolites; C006903:carbopol 940; C029899:imidazole; D004317:Doxorubicin