title: [Peroral endoscopic full and partial-thickness myotomy. A viability study in an animal model].
abstract: BACKGROUND
  Peroral endoscopic myotomy has recently been developed and performed on patients with good results.
  
  
  OBJECTIVE
  To evaluate the technical feasibility of peroral endoscopic full-thickness and partial thickness myotomy in a porcine model.
  
  
  METHODS
  Eighteen criollo pigs were randomly assigned to 2 groups: group A (partial-thickness myotomy) and group B (full-thickness myotomy). The mucosal defect proximal to the myotomy site was left open. On the seventh postoperative day the pig was euthanized and follow-up surgical exploration was performed. The duration of each procedure, postoperative progression of the animal, complications, and anatomopathologic findings were registered.
  
  
  RESULTS
  The procedure was viable in all the pigs. The mean surgery duration was 81±35.3min (group A 51.11±11.12, group B 111±22.61; P<.05). The main complication during myotomy was subcutaneous emphysema (16%). The histopathologic study of the group A surgical specimens reported complete circular myotomy in all cases, and complete circular and longitudinal myotomy was reported in 100% of the group B sample.
  
  
  CONCLUSIONS
  The endoscopic myotomy technique is feasible. Endoscopic partial-thickness myotomy was associated with shorter surgery duration and better results during the intraoperative period and the 7-day follow-up.
authors.affiliation: Residente de Endoscopia Digestiva, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México. Electronic address: radheyadqg@gmail.com.
authors.forename: C D
authors.initials: CD
authors.lastname: Quiroz-Guadarrama
authors.affiliation: Jefe del Servicio de Endoscopia Digestiva, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: M
authors.initials: M
authors.lastname: Rojano-Rodríguez
authors.affiliation: Jefe de la División de Atención Médica, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: J J
authors.initials: JJ
authors.lastname: Herrera-Esquivel
authors.affiliation: Jefe de Cirugía Experimental y Bioterio, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: F
authors.initials: F
authors.lastname: de la Concha-Bermejillo
authors.affiliation: Adscrito al Servicio de Cirugía Endoscópica, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: L S
authors.initials: LS
authors.lastname: Romero-Loera
authors.affiliation: Adscrito al Servicio de Anatomía Patológica, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: I
authors.initials: I
authors.lastname: Estrada-Moscoso
authors.affiliation: Residente de Fisiología Digestiva, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: I
authors.initials: I
authors.lastname: Del Rio-Suarez
authors.affiliation: Residente de Endoscopia Digestiva, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: J M
authors.initials: JM
authors.lastname: Morales-Vargas
authors.affiliation: Residente de Endoscopia Digestiva, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: M F
authors.initials: MF
authors.lastname: Torres-Ruiz
authors.affiliation: Adscrito al Servicio de Endoscopia Gastrointestinal, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: J A
authors.initials: JA
authors.lastname: Gonzalez-Angulo
authors.affiliation: Adscrito al Servicio de Endoscopia Gastrointestinal, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: J L
authors.initials: JL
authors.lastname: Beristain-Hernandez
authors.affiliation: Adscrito al Servicio de Endoscopia Gastrointestinal, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: J
authors.initials: J
authors.lastname: Alonso-Lárraga
authors.affiliation: Jefe de la División de Cirugía General y Endoscópica, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: E
authors.initials: E
authors.lastname: Cárdenas-Lailson
authors.affiliation: Director General, Hospital General Dr. Manuel Gea Gonzalez, S.S.A. México, México, D.F., México.
authors.forename: M
authors.initials: M
authors.lastname: Moreno-Portillo
mesh_terms: D000758:Anesthesia; D000818:Animals; D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects / Q000379:methods*; D004931:Esophageal Achalasia / Q000601:surgery; D049630:Esophageal Sphincter, Lower / Q000601:surgery; D004947:Esophagus / Q000601:surgery*; D005260:Female; D009055:Mouth / Q000601:surgery*; D009132:Muscles / Q000601:surgery; D057605:Natural Orifice Endoscopic Surgery; D019106:Postoperative Hemorrhage; D013552:Swine
keywords: Miotomía endoscópica de espesor parcial; Miotomía endoscópica por vía oral; Miotomía endoscópica por vía oral de espesor total; Modelo porcino; Peroral endoscopic full-thickness myotomy; Peroral endoscopic myotomy; Peroral endoscopic partial-thickness myotomy; Porcine model