title: Evaluation of antimicrobial activity of the methanol extracts from 8 traditional medicinal plants.
abstract: The methanol extract of 12 medicinal plants were evaluated for its antibacterial activity against Gram-positive (5 strains) and Gram-negative bacteria (10 strains) by assay for minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) . The antibacterial activity was determined by an agar dilution method (according to the guidelines of Clinical and Laboratory Standard Institute) . All the compounds (12 extracts) of the 8 medicinal plants (leaf or root) were active against both Gram-negative and Gram-positive bacteria. Gram-negative showed a more potent action than Gram positive bacteria. The MIC concentrations were various ranged from 0.6 μg/ml to 5000 μg/ml. The lowest MIC (0.6 μg/ml) and MBC (1.22 μg/ml) values were obtained with extract on 4 and 3 of the 15 microorganisms tested, respectively.
authors.affiliation: Department of Pharmacology & Toxicology, College of Veterinary Medicine, Gyeongsang National University (Institute of Animal Science) , Jinju 660-701.
authors.forename: Chang-Geun
authors.initials: CG
authors.lastname: Kang
authors.forename: Dae-Sik
authors.initials: DS
authors.lastname: Hah
authors.forename: Chung-Hui
authors.initials: CH
authors.lastname: Kim
authors.forename: Young-Hwan
authors.initials: YH
authors.lastname: Kim
authors.forename: Euikyung
authors.initials: E
authors.lastname: Kim
authors.forename: Jong-Shu
authors.initials: JS
authors.lastname: Kim
keywords: Antimicrobial activity; agar dilution method .; methanol extract; minimum bacterial concentration (MBC); minimum inhibitory concentration (MIC); traditional medicinal plants