title: Complete response of primary bladder adenocarcinoma with the FOLFOX4 regimen.
abstract: BACKGROUND
  Primary adenocarcinoma of the bladder is a very rare disease that is difficult to treat. In this paper, we report the second case in the literature with primary mucinous adenocarcinoma of the bladder which showed complete response to FOLFOX4 (fluorouracil, leucovorin, oxaliplatin) chemotherapy regimen.
  
  
  METHODS
  A 41-year-old man was admitted to our hospital with a diagnosis of primary adenocarcinoma of the bladder. Due to the similarity in histology with colon carcinoma, a FOLFOX4 regimen was started. Complete response was achieved at the end of this treatment. Today the patient is free of local or systemic disease.
  
  
  CONCLUSIONS
  FOLFOX4 regimen may be a treatment option for primary adenocarcinoma of the bladder.
authors.affiliation: Department of Medical Oncology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.
authors.forename: A M
authors.initials: AM
authors.lastname: Tatli
authors.forename: M
authors.initials: M
authors.lastname: Uysal
authors.forename: S S
authors.initials: SS
authors.lastname: Goksu
authors.forename: S
authors.initials: S
authors.lastname: Gunduz
authors.forename: D
authors.initials: D
authors.lastname: Arslan
authors.forename: M
authors.initials: M
authors.lastname: Ozdogan
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy*; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D007150:Immunohistochemistry; D002955:Leucovorin / Q000627:therapeutic use; D008297:Male; D009362:Neoplasm Metastasis; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy*
chemical_list: D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil