title: Uterine myomas treated with microwave ablation: the agreement between ablation volumes obtained from contrast-enhanced sonography and enhanced MRI.
abstract: OBJECTIVE
  This study explores the agreement between ablated uterine myoma volumes obtained from contrast-enhanced sonography and enhanced magnetic resonance imaging (MRI) after microwave ablation therapy.
  
  
  METHODS
  Twenty uterine myomas in 18 patients (average size: 5.56 ± 1.26 cm) were successfully treated by microwave ablation. Contrast-enhanced sonography and enhanced MRI were performed within 7 days after the treatment. The ablation range of uterine myomas was observed and the ablation volume was calculated. By using the intraclass correlation coefficient (ICC) and Bland-Altman regression analysis, the agreement between ablated uterine myoma volumes obtained from contrast-enhanced sonography and enhanced MRI after microwave ablation therapy was analysed.
  
  
  RESULTS
  The ablated volume ranged from 13.66 to 135.27 cm(3) after ablation, and the mean volume was 66.59 ± 35.71 cm(3) by using contrast-enhanced sonography. Respectively, the ablated volume ranged from 10.88 to 137.83 cm(3), and the mean volume was 66.81 ± 35.45 cm(3) by using enhanced MRI. The limits of agreement between the two methods were (-10.83 cm(3), 8.39 cm(3)), ICC was 0.991 (F = 209.61, P < 0.05), and 95% confidence interval is (0.976, 0.996). The results revealed a good agreement between the two examination methods of contrast-enhanced sonography and enhanced MRI.
  
  
  CONCLUSIONS
  Contrast-enhanced sonography and enhanced MRI can be used interchangeably in observing the ablation range of uterine myomas treated with microwave ablation. Contrast-enhanced sonography can be used as a preferred non-invasive examination and for follow-up. Meanwhile, enhanced MRI can be used to comprehensively determine the relationships among uterine myomas, the entire uterus, and surrounding tissues.
authors.affiliation: Ultrasound Department, First Affiliated Hospital of Chinese PLA General Hospital , Beijing .
authors.forename: Feng
authors.initials: F
authors.lastname: Lei
authors.forename: Zhang
authors.initials: Z
authors.lastname: Jing
authors.forename: Wen
authors.initials: W
authors.lastname: Bo
authors.forename: Hu
authors.initials: H
authors.lastname: Dongmei
authors.forename: Li
authors.initials: L
authors.lastname: Zhencai
authors.forename: Jiang
authors.initials: J
authors.lastname: Xue
authors.forename: Wang
authors.initials: W
authors.lastname: Fang
authors.forename: Zhou
authors.initials: Z
authors.lastname: Hongyu
authors.forename: Ren
authors.initials: R
authors.lastname: Jintao
mesh_terms: D055011:Ablation Techniques; D000328:Adult; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000000981:diagnostic imaging / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008872:Microwaves; D008875:Middle Aged; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*