title: Computational analysis of endometrial photocoagulation with diffusing optical device.
abstract: A balloon-catheter optical diffuser for endometrial treatment was evaluated with computational thermal analysis. Various catheter materials and dimensions were implemented to identify the optimal design for the device. Spatial and temporal development of temperature during 30-sec irradiation of 532-nm light demonstrated thermal insulation effects of polyurethane on temperature increase up to 384 K, facilitating the irreversible denaturation. The current model revealed the degree of thermal coagulation 13% thicker than experimental results possibly due to lack of tissue dynamics and light intensity distribution. In combination with photon distribution, the analytical simulation can be a feasible tool to optimize the new optical diffuser for efficient and safe endometrial treatment.
authors.affiliation: Department of Biomedical Engineering, Pukyong National University, Busan 608-737, South Korea.
authors.forename: Jinhee
authors.initials: J
authors.lastname: Kwon
authors.forename: Chang-Yong
authors.initials: CY
authors.lastname: Lee
authors.forename: Junghwan
authors.initials: J
authors.lastname: Oh
authors.forename: Hyun Wook
authors.initials: HW
authors.lastname: Kang
keywords: (000.4430) Numerical approximation and analysis; (120.6810) Thermal effects; (170.1610) Clinical applications; (170.3890) Medical optics instrumentation; (170.4440) ObGyn