title: [Effects of the umbilical blood stem cells in experimental injury of myocardium].
abstract: Morphological, functional signs of myocardium affection and tolerance to physical loading in animals with isoproterenol-induced affection of myocardium after transplantation of a nuclear-containing cells (NCC) of umbilical blood were analyzed in comparison with a natural course of the model. There was proved, that a transplantation of a NCC promotes acceleration of processes of regeneration and restoration of the damaged myocardium in experimental animals. There were estimated the changes in localization of the transplanted NCC in the zone of damage, and capacity of the peripheral blood NCC, while they were transplanted, using intravenous injection, to migrate into the damage zone. The experimental data obtained need further complex analysis and permit to wait a positive effect while performing clinical investigations in the patients, suffering chronic diseases of the heart.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Poliachenko
authors.forename: A V
authors.initials: AV
authors.lastname: Habriielian
authors.forename: T M
authors.initials: TM
authors.lastname: Domans'kyĭ
authors.forename: V Ĭ
authors.initials: VĬ
authors.lastname: Smorzhevskyĭ
authors.forename: V F
authors.initials: VF
authors.lastname: Onishchenko
authors.forename: A P
authors.initials: AP
authors.lastname: Mazur
authors.forename: S V
authors.initials: SV
authors.lastname: Romanova
authors.forename: I V
authors.initials: IV
authors.lastname: Kudlaĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Iakushev
authors.forename: P P
authors.initials: PP
authors.lastname: Klymenko
authors.forename: O V
authors.initials: OV
authors.lastname: Kuchuk
authors.forename: V M
authors.initials: VM
authors.lastname: Kyryk
authors.forename: M D
authors.initials: MD
authors.lastname: Kuchma
authors.forename: H S
authors.initials: HS
authors.lastname: Lobyntseva
authors.forename: R V
authors.initials: RV
authors.lastname: Saliutin
authors.forename: V A
authors.initials: VA
authors.lastname: Shabliĭ
mesh_terms: D000818:Animals; D036101:Cord Blood Stem Cell Transplantation; D015925:Cryopreservation; D005260:Female; D005312:Fetal Blood / Q000166:cytology* / Q000502:physiology / Q000637:transplantation; D006801:Humans; D007545:Isoproterenol; D051379:Mice; D009203:Myocardial Infarction / Q000139:chemically induced / Q000473:pathology / Q000628:therapy*; D009206:Myocardium / Q000473:pathology*; D032383:Myocytes, Cardiac / Q000473:pathology*; D012038:Regeneration / Q000502:physiology; D014183:Transplantation, Heterologous
chemical_list: D007545:Isoproterenol