title: Clathrin-mediated endocytosis and adaptor proteins.
abstract: Macromolecules gain access to the cytoplasm of eukaryotic cells using one of several ways of which clathrin-dependent endocytosis is the most researched. Although the mechanism of clathrin-mediated endocytosis is well understood in general, novel adaptor proteins that play various roles in ensuring specific regulation of the mentioned process are being discovered all the time. This review provides a detailed account of the mechanism of clathrin-mediated internalization of activated G protein-coupled receptors, as well as a description of the major proteins involved in this process.
authors.affiliation: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Miklukho-Maklaya St., 16/10, Moscow, Russia, 117997.
authors.forename: N V
authors.initials: NV
authors.lastname: Popova
authors.forename: I E
authors.initials: IE
authors.lastname: Deyev
authors.forename: A G
authors.initials: AG
authors.lastname: Petrenko
keywords: adaptor proteins; clathrin; endocytosis