title: [Perspectives of male contraception].
abstract: The principle of suppressive methods of male contraception is to repress the sperm production and its functions by hormonal, chemical, physical, immunological or other ways. Of hormonal methods, the most perspective seems to be the steroid blockade of spermatogenesis. In horizon of ten years, it might be expected that the first male hormonal contraception will be available in form of injections or implants, however the "male pill" will not become a reality in the near future. Blockade of calcium channels by means of pharmacological inhibitors seems to be another promising mechanism of sperm functions inhibition. Based on the results of research of last two decades, the method of "reversible vasectomy" might be accessible, too.
authors.forename: Daniel
authors.initials: D
authors.lastname: Driák
authors.forename: Ivana
authors.initials: I
authors.lastname: Svandová
mesh_terms: D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D003267:Contraception / Q000379:methods*; D003272:Contraceptive Agents, Male / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D013091:Spermatogenesis; D014659:Vasectomy; D014669:Vasovasostomy
chemical_list: D002121:Calcium Channel Blockers; D003272:Contraceptive Agents, Male