title: DNA strand-displacement-induced fluorescence enhancement for highly sensitive and selective assay of multiple microRNA in cancer cells.
abstract: We report a new strategy for evaluating multiple miRNA expressions in cancer cells based on DNA strand-displacement-induced fluorescence enhancement. This assay has the ability to discriminate the target from even single-base mismatched sequences or other miRNAs.
authors.affiliation: Jiangsu Key Laboratory of New Power Batteries, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, P. R. China. cxcai@njnu.edu.cn.
authors.forename: Ping
authors.initials: P
authors.lastname: Wu
authors.forename: Yunqiu
authors.initials: Y
authors.lastname: Tu
authors.forename: Yingdan
authors.initials: Y
authors.lastname: Qian
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.forename: Chenxin
authors.initials: C
authors.lastname: Cai
mesh_terms: D020137:Base Pair Mismatch; D045744:Cell Line, Tumor; D004247:DNA / Q000378:metabolism*; D005456:Fluorescent Dyes / Q000737:chemistry; D006108:Graphite / Q000737:chemistry; D061307:Human Umbilical Vein Endothelial Cells; D006801:Humans; D035683:MicroRNAs / Q000378:metabolism*; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D060888:Real-Time Polymerase Chain Reaction
chemical_list: D005456:Fluorescent Dyes; D035683:MicroRNAs; D006108:Graphite; D004247:DNA