title: Metastatic squamous cell carcinoma urinary bladder coexisting with tuberculosis in pelvic lymph nodes.
abstract: Squamous cell carcinoma (SCC) of the urinary bladder is usually associated with Schistosoma haematobium and chronic bladder irritation. We report a case of coexistent metastatic SCC and tuberculosis in obturator lymph nodes in radical cystoprostatectomy and pelvic lymphadenectomy specimens. Though tubercular iliac lymphadenitis and metastatic transitional carcinoma following intravesical BCG has been reported, the concurrent presence of non-transitional cell cancer and primary lymph nodal tuberculosis in regional lymph nodes is rare. This case is reported to highlight the paucity of management guidelines available presently in the treatment of such patients who require systemic chemotherapy and antitubercular therapy.
authors.affiliation: Department of Urology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
authors.forename: Vilvapathy Senguttuvan
authors.initials: VS
authors.lastname: Karthikeyan
authors.forename: Ramanitharan
authors.initials: R
authors.lastname: Manikandan
authors.forename: Sajini Elizabeth
authors.initials: SE
authors.lastname: Jacob
authors.forename: P Puvai
authors.initials: PP
authors.lastname: Murugan
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000628:therapy; D003131:Combined Modality Therapy / Q000379:methods; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D010388:Pelvis; D016896:Treatment Outcome; D014388:Tuberculosis, Lymph Node / Q000150:complications* / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000628:therapy
chemical_list: D000995:Antitubercular Agents