title: Extremely rare coincidence of non-radiographic axial spondyloarthropathy HLA-B27 positive and Stiff Person Syndrome--rheumatologist point of view.
abstract: Stiff Person Syndrome (SPS) is a rare autoimmune neurological disorder characterized by progressive stiffness and rigidity of truncal muscles accompanied with co-contraction of agonist-antagonist muscles. Our 51-year-old female patient was presented for the first time to physiatrists in 2006 and diagnosed with axial-spondyloarthropathy (SpA) HLA-B27 positive. SPS was diagnosed 7 years after initial symptoms. SPS should be taken into consideration in HLA-B27 positive patients if stiffness of paravertebral and abdominal muscles progresses during SpA therapy.
authors.affiliation: a Department of Rehabilitation Medicine and Rheumatology , University Hospital Split, School of Medicine in Split , Split , Croatia.
authors.forename: Ivanka
authors.initials: I
authors.lastname: Marinović
authors.affiliation: a Department of Rehabilitation Medicine and Rheumatology , University Hospital Split, School of Medicine in Split , Split , Croatia.
authors.forename: Dinko
authors.initials: D
authors.lastname: Pivalica
authors.affiliation: a Department of Rehabilitation Medicine and Rheumatology , University Hospital Split, School of Medicine in Split , Split , Croatia.
authors.forename: Jure
authors.initials: J
authors.lastname: Aljinović
authors.affiliation: a Department of Rehabilitation Medicine and Rheumatology , University Hospital Split, School of Medicine in Split , Split , Croatia.
authors.forename: Tonko
authors.initials: T
authors.lastname: Vlak
authors.affiliation: a Department of Rehabilitation Medicine and Rheumatology , University Hospital Split, School of Medicine in Split , Split , Croatia.
authors.forename: Ela
authors.initials: E
authors.lastname: Škorić
authors.affiliation: b Department of Rheumatology and Clinical Immunology , University Hospital Split, School of Medicine in Split , Split , Croatia.
authors.forename: Dušanka
authors.initials: D
authors.lastname: Martinović Kaliterna
mesh_terms: D005260:Female; D015796:HLA-B27 Antigen / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000276:immunology*; D025242:Spondylarthropathies / Q000150:complications* / Q000276:immunology; D016750:Stiff-Person Syndrome / Q000150:complications* / Q000276:immunology
chemical_list: D015796:HLA-B27 Antigen
keywords: Anti-GAD; HLA-B27; Spondyloarthropathy; Stiff Person Syndrome; Truncal rigidity