title: Eisenmenger syndrome in an adult patient with a large patent ductus arteriosus.
abstract: This is the case of a young female who was seen at our adult congenital heart disease and pulmonary hypertension service (Royal Brompton Hospital, London, UK) at the age of 17 years. She initially presented at the age of 4 years with increasing shortness of breath. At that time, there was differential cyanosis with clubbing and lower oxygen saturations in the toes (82%) compared with her fingers (95%). On echocardiography there was evidence of severe pulmonary hypertension and a large patent ductus arteriosus (PDA) with low velocity bidirectional shunting. She underwent cardiac catheterisation at the time which showed a pulmonary arterial pressure equal to that of the aorta.
authors.affiliation: Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and the National Heart and Lung Institute, Imperial College, London, UK.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Dimopoulos
mesh_terms: D000293:Adolescent; D000959:Antihypertensive Agents / Q000627:therapeutic use; D062186:Arterial Pressure; D006328:Cardiac Catheterization; D004374:Ductus Arteriosus, Patent / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D004541:Eisenmenger Complex / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D011651:Pulmonary Artery / Q000503:physiopathology; D011652:Pulmonary Circulation; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents