title: [Repetitive transcranial magnetic stimulation (rTMS) therapy for Parkinson disease].
abstract: In repetitive transcranial magnetic stimulation (rTMS), repetitive cortical stimulation induces after-effects, and rTMS has been applied as a treatment for various neurological or psychiatric disorders. Animal studies demonstrated that cortical stimulation could improve Parkinsonism, and a meta-analysis of clinical studies showed efficacy of high frequency rTMS. We conducted two clinical trials of supplementary motor area rTMS therapy for Parkinson's disease, and reported long-lasting efficacy. Other studies targeted specified aspects of Parkinson's disease, or utilized newly developed stimulation protocols. rTMS therapy for PD is a promising area, and can be an important treatment option in the near future.
authors.affiliation: Department of Neurology, The University of Tokyo.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Shirota
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D019317:Evidence-Based Medicine; D006801:Humans; D015201:Meta-Analysis as Topic; D009044:Motor Cortex; D010300:Parkinson Disease / Q000628:therapy*; D050781:Transcranial Magnetic Stimulation / Q000379:methods