title: Osseointegration of oral implants after delayed placement in rabbits: a microcomputed tomography and histomorphometric study.
abstract: OBJECTIVE
  This study compared osseointegration of implants placed 14 days after implant site preparation with that of immediately placed implants in rabbit femurs.
  
  
  METHODS
  Implants were placed bilaterally in the femoral condyles of 12 rabbits. On one side, the implants were placed 14 days after osteotomy, and the other side received implants immediately after osteotomy. Healing was assessed by microcomputed tomography and histomorphometry.
  
  
  RESULTS
  The delayed implants (placed 14 days after osteotomy) showed better osseointegration than the immediately placed implants. Bone-to-implant contact and bone volume, as assessed by histomorphometry and microcomputed tomography, were significantly higher for the implants placed after 14 days.
  
  
  CONCLUSIONS
  From this study, it can be concluded that early osteotomy bed preparation and placement of implants after a 2-week delay predisposes to better bone-implant interface healing.
authors.forename: Sukumaran
authors.initials: S
authors.lastname: Anil
authors.forename: Vincent M J I
authors.initials: VM
authors.lastname: Cuijpers
authors.forename: Reghunathan S
authors.initials: RS
authors.lastname: Preethanath
authors.forename: Abdullah Al Farraj
authors.initials: AA
authors.lastname: Aldosari
authors.forename: John A
authors.initials: JA
authors.lastname: Jansen
mesh_terms: D000818:Animals; D015921:Dental Implants; D005269:Femur; D016348:Osseointegration / Q000502:physiology*; D010027:Osteotomy; D011817:Rabbits; D013997:Time Factors; D014945:Wound Healing / Q000502:physiology*; D055114:X-Ray Microtomography
chemical_list: D015921:Dental Implants