title: The mother of all endocytosis.
abstract: Massive endocytosis is initiated by a series of steps that involve a sudden influx of calcium ions, changes in mitochondria, and modification of surface proteins by lipids. A better understanding of this process could lead to new approaches to reducing the tissue damage that is caused by heart attacks.
authors.affiliation: David E Clapham is in the Howard Hughes Medical Institute, Department of Cardiology, Boston Children's Hospital, Boston, United States and the Department of Neurobiology, Harvard Medical School, Boston, United States dclapham@enders.tch.harvard.edu.
authors.forename: David E
authors.initials: DE
authors.lastname: Clapham
mesh_terms: D000818:Animals; D004705:Endocytosis; D008928:Mitochondria / Q000378:metabolism*; D019308:Palmitic Acid / Q000378:metabolism*
chemical_list: D019308:Palmitic Acid
keywords: endocytosis; palmitoylation; patch clamp; permeability transition pore