title: 2-Arylacetic anhydrides as ammonium enolate precursors.
abstract: Readily prepared 2-arylacetic anhydrides act as convenient ammonium enolate precursors in isothiourea (HBTM-2.1)-mediated catalytic asymmetric intermolecular Michael addition-lactonisation processes, giving diverse synthetic building blocks in good yield with high diastereo- and enantiocontrol (up to 98 : 2 dr and >99% ee).
authors.affiliation: EaStCHEM, School of Chemistry, University of St Andrews, North Haugh, St Andrews, KY16 9ST, UK. ads10@st-andrews.ac.uk.
authors.forename: Louis C
authors.initials: LC
authors.lastname: Morrill
authors.forename: Lyndsay A
authors.initials: LA
authors.lastname: Ledingham
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Couturier
authors.forename: Jasmine
authors.initials: J
authors.lastname: Bickel
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Harper
authors.forename: Charlene
authors.initials: C
authors.lastname: Fallan
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Smith