title: [The CD100 semaphorin expression on peripheral blood T-lymphocytes in patients with relapsing-remitting multiple sclerosis].
abstract: The expression of CD100 semaphorin by the intact peripheral blood T lymphocytes in multiple sclerosis (MS) has been studied. The level of middle florescence intensity (MFI) and the number of B-lymphocytes bearing CD72 were evaluated. There were significant differences in the level of CD100 in patients compared to healthy volunteers. These data suggest the use of semaphorin as a possible therapeutic target in pathological inflammation in MS.
authors.forename: T N
authors.initials: TN
authors.lastname: Trushnikova
authors.forename: T V
authors.initials: TV
authors.lastname: Baĭdina
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Danchenko
authors.forename: E M
authors.initials: EM
authors.lastname: Kuklina
authors.forename: I V
authors.initials: IV
authors.lastname: Nekrasova
mesh_terms: D000328:Adult; D015703:Antigens, CD / Q000096:biosynthesis* / Q000276:immunology; D000944:Antigens, Differentiation, B-Lymphocyte / Q000276:immunology; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000097:blood / Q000276:immunology*; D039961:Semaphorins / Q000096:biosynthesis* / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D015703:Antigens, CD; D000944:Antigens, Differentiation, B-Lymphocyte; C093224:CD100 antigen; C064228:CD72 protein, human; D039961:Semaphorins