title: Ecotoxicological impact of MSW landfills: assessment of teratogenic effects by means of an adapted FETAX assay.
abstract: The introduction of chemical products into the environment can cause long-term effects on the ecosystems. Increasing efforts are being made to determine the extent of contamination in particularly affected areas using diverse methods to assess the ecotoxicological impact. We used a modified Frog Embrio Toxicity Assay-Xenopus method to determine the extent of toxicological load in different sample soils obtained near three municipal solid waste landfills in Catalonia (Spain). The results show that the Garraf landfill facility produces more embryotoxic damage to the surroundings, than the others ones: Can Mata landfill and Montferrer-Castellbó landfill. The aim of this work is to demonstrate how different management of complex sources of contamination as the controlled dumping sites can modulate the presence of toxics in the environment and their effects and through this, help determine the safer way to treat these wastes. To this effect some conceptual modifications have been made on the established American Society for Testing and Materials protocol. The validity of the new model, both as to model of calculation as to protocol, has been demonstrated in three different sites with complex sources of contamination.
authors.affiliation: Experimental Toxicology and Ecotoxicology Unit (CERETOX), Barcelona Science Park, Baldiri i Reixac 10-12, 08028, Barcelona, Spain, jlapuente@pcb.ub.cat.
authors.forename: J
authors.initials: J
authors.lastname: de Lapuente
authors.forename: J
authors.initials: J
authors.lastname: González-Linares
authors.forename: E
authors.initials: E
authors.lastname: Pique
authors.forename: M
authors.initials: M
authors.lastname: Borràs
mesh_terms: D000818:Animals; D004785:Environmental Pollutants / Q000633:toxicity*; D012987:Soil / Q000737:chemistry; D013030:Spain; D013723:Teratogens / Q000633:toxicity*; D018675:Toxicity Tests / Q000191:economics / Q000379:methods*; D064091:Waste Disposal Facilities; D014981:Xenopus / Q000378:metabolism*
chemical_list: D004785:Environmental Pollutants; D012987:Soil; D013723:Teratogens