title: Periodontitis: oral complication of diabetes.
abstract: Periodontitis is a common, chronic, inflammatory disease in which the supporting apparatus of the teeth is gradually destroyed, resulting in tooth mobility and tooth loss. Susceptibility to periodontitis is increased approximately three-fold in people with diabetes. Hyperglycemia leads to exacerbated tissue destruction and the clinical signs of periodontitis. There is evidence to support a two-way relationship between periodontitis and diabetes; not only does diabetes increase the risk for periodontitis, but periodontitis is associated with compromised glycemic control. Cooperation between health care teams would benefit the treatment of patients with diabetes and periodontitis.
authors.affiliation: School of Dental Sciences, Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4BW, UK. Electronic address: philip.preshaw@ncl.ac.uk.
authors.forename: Philip M
authors.initials: PM
authors.lastname: Preshaw
authors.forename: Susan M
authors.initials: SM
authors.lastname: Bissett
mesh_terms: D001786:Blood Glucose / Q000378:metabolism; D048909:Diabetes Complications / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D009059:Mouth Diseases / Q000209:etiology; D010518:Periodontitis / Q000188:drug therapy / Q000209:etiology* / Q000628:therapy
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents
keywords: Diabetes; Diabetes complications; Gingivitis; Glycated hemoglobin; HbA1c; Inflammation; Periodontal diseases; Periodontitis