title: [Observation on clinical effect of ZHUANG medicine mediated thread moxibustion combined with medication for patients with ulcerative colitis].
abstract: OBJECTIVE
  To observe the clinical effect and safety of Sulfasalazine (SASP) combined with ZHUANG medicine mediated thread moxibustion (ZMMTM) for patients with mild and moderate ulcerative colitis (UC).
  
  
  METHODS
  A total of 46 UC patients were randomly and equally divided into moxibustion group (SASP combined with ZMMTM) and SASP medication group. Patients of both groups were treated by oral administration of SASP (1 g, tid) for six weeks. For patients of the moxibustion group, ZMMTM was applied to points Tianshu (ST 25), Qihai (CV 6), Guanyuan (CV 4), and Dachangshu (BL 25), once a day, for 20 times. The therapeutic effect was assessed according to Schroeder and colleagues' method (1987), scores of Baron' s endoscope scale (0 - 9 scoring standards, 1964), 0 - 3 scoring standards of activity indexes (including 4 items of diarrhea, hemorrhage, mucosal appearance and doctors' evaluation), respectively.
  
  
  RESULTS
  Of the two 32 UC patients in the medication and moxibustion groups, 6 and 9 had a complete remission in their symptoms, 6 and 7 experienced a remarkable improvement, 5 and 6 were effective, and 6 and 1 was invalid, with the effective rates being 73.91% and 95.65%, respectively. Following the treatment, both endoscopic score and activity index in the moxibustion group were significantly lower than those of the medication group (P < 0.05).
  
  
  CONCLUSIONS
  ZMMTM combined with medication is significantly superior to simple medication in relieving clinical symptoms of mild and moderate UC patients.
authors.affiliation: Department of Colorectal and Anal Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China. acme32@163.com
authors.forename: Lei-Chang
authors.initials: LC
authors.lastname: Zhang
authors.forename: Sen
authors.initials: S
authors.lastname: Zhang
authors.forename: Wu
authors.initials: W
authors.lastname: Zhong
authors.forename: Jun-Xian
authors.initials: JX
authors.lastname: Long
authors.forename: Xiu-Ning
authors.initials: XN
authors.lastname: Li
authors.forename: Li-Sheng
authors.initials: LS
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000188:drug therapy / Q000628:therapy*; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D005765:Gastrointestinal Agents / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009071:Moxibustion; D012460:Sulfasalazine / Q000008:administration & dosage*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D004365:Drugs, Chinese Herbal; D005765:Gastrointestinal Agents; D012460:Sulfasalazine