title: [Genetic polymorphisms of 16 non-CODIS STR loci in Beijing Han population].
abstract: OBJECTIVE
  To investigate the genetic polymorphisms of 16 non-CODIS loci (D6S477, D22-GATA198B05, D15S659, D8S1132, D3S3045, D17S1290, D14S608, D2S441, D18S535, D13S325, D10S1435, DlS2368, DIS1656, D7S3048, D10S1248 and D19S253) in Beijing Han population.
  
  
  METHODS
  The DNA of 300 unrelated individuals in Beijing Han population were PCR amplified using GoldeneyeM DNA identification system 18NC kit, and the PCR products were analyzed by electrophoresis through 3130XL genetic analyzer. The fragment sizes of alleles were taken subsequently by GeneMapper v3.2.
  
  
  RESULTS
  The distributions of genotype frequencies of 16 non-CODIS STR loci in Beijing Han population satisfied the Hardy-Weinberg equilibration. The population genetic parameters were obtained as followings: heterozygosity was 0.677-0.873; discrimination power, 0.890-0.967; probability of paternity exclusion, 0.393-0.741; and polymorphism information content, 0.706-0.853.
  
  
  CONCLUSIONS
  These 16 non-CODIS STR loci show great genetic polymorphisms in Beijing Han population, and are useful for the research of population genetics and forensic application.
authors.affiliation: Forensic Science Service of the Beijing Public Security Bureau, Beijing 100192, China. qingxiazhang@sina.com
authors.forename: Qing-Xia
authors.initials: QX
authors.lastname: Zhang
authors.forename: Jian
authors.initials: J
authors.lastname: Yang
authors.forename: Ya-Cheng
authors.initials: YC
authors.lastname: Liu
authors.forename: Hui
authors.initials: H
authors.lastname: Tang
authors.forename: Zhang-Ping
authors.initials: ZP
authors.lastname: Jiao
mesh_terms: D000483:Alleles; D044466:Asian People / Q000208:ethnology / Q000235:genetics*; D002681:China; D016172:DNA Fingerprinting; D005260:Female; D053803:Forensic Genetics; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D006579:Heterozygote; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
chemical_list: D005819:Genetic Markers