title: [Antibodies to Saccharomyces cerevisiae as predictors of the complicated flow of Crohn disease].
abstract: Among the 143 patients in the acute phase of IBD the ASCA detected in 34 people, accounting for 23.8%, and in 60 patients with CD the increased level of ASCA was found in 24 people (40%), in 83 patients with UC the increased level of ASCA was found in 9 (10, 8%). The appearance of antibodies to Saccharomyces cerevisiae in the blood serum of patients with CD is regarded as a prognostically unfavorable sign, indicating that the disease may have a complicated course. Also, high titers of ASCA combined with complicated CD, requiring surgical treatment.
authors.forename: V É
authors.initials: VÉ
authors.lastname: Sagynbaeva
authors.forename: L B
authors.initials: LB
authors.lastname: Lazebnik
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000908:Antibodies, Fungal / Q000097:blood* / Q000276:immunology; D003424:Crohn Disease / Q000097:blood* / Q000276:immunology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012441:Saccharomyces cerevisiae / Q000276:immunology*
chemical_list: D000908:Antibodies, Fungal