title: Concentrations of persistent organic pollutants (POPs) in human blood samples from Mexico City, Mexico.
abstract: Studies in Mexico have demonstrated exposure to persistent organic pollutants (POPs) in people living in different sites through the country. However, studies evaluating exposure to POPs in people living in Mexico City (one of most contaminated places in the world) are scarce. Therefore, the aim of this study was to assess the levels of polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT) and its metabolite dichlorodiphenyldichloroethylene (DDE) in the blood as exposure biomarkers in people living in Mexico City. A total of 123 participants (blood donors aged 20-60 years) were recruited during 2010 in Mexico City. Quantitative analyses of blood samples were performed using gas chromatography coupled with mass spectrometry. Levels of the assessed compounds ranged from non-detectable (<LOD) to 350 ng/g lipid; from 8.20 to 91.0 ng/g lipid and from <LOD to 34.0 ng/g lipid for total PBDEs, total PCBs and total DDT, respectively. The current study indicates POP exposure in the people assessed and highlights the need for further biomonitoring studies of these POPs in the region. In this regard, biomonitoring of toxins on a global scale may be the first step towards the prevention of toxin-induced illnesses in the population.
authors.affiliation: Laboratorio de Toxicología Molecular, Centro de Investigación Aplicada en Ambiente y Salud (CIAAS), Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Mexico; Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico; Unidad Académica Multidisciplinaria Zona Media, Universidad Autónoma de San Luis Potosí, Rioverde, San Luis Potosí, Mexico.
authors.forename: Sandra
authors.initials: S
authors.lastname: Orta-García
authors.affiliation: Laboratorio de Toxicología Molecular, Centro de Investigación Aplicada en Ambiente y Salud (CIAAS), Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Mexico; Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico.
authors.forename: Francisco
authors.initials: F
authors.lastname: Pérez-Vázquez
authors.affiliation: Laboratorio de Toxicología Molecular, Centro de Investigación Aplicada en Ambiente y Salud (CIAAS), Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Mexico; Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico.
authors.forename: Carolina
authors.initials: C
authors.lastname: González-Vega
authors.affiliation: Laboratorio de Toxicología Molecular, Centro de Investigación Aplicada en Ambiente y Salud (CIAAS), Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Mexico; Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico.
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Varela-Silva
authors.affiliation: Centro de Innovación Aplicada en Tecnologías Competitivas (CIATEC), León, Guanajuato, Mexico.
authors.forename: Lidia
authors.initials: L
authors.lastname: Hernández-González
authors.affiliation: Laboratorio de Toxicología Molecular, Centro de Investigación Aplicada en Ambiente y Salud (CIAAS), Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Mexico; Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico; Facultad de Enfermería, Universidad Autónoma de Zacatecas, Mexico. Electronic address: ivan.perez@uaslp.mx.
authors.forename: Iván
authors.initials: I
authors.lastname: Pérez-Maldonado
mesh_terms: D000328:Adult; D003634:DDT / Q000097:blood; D003633:Dichlorodiphenyl Dichloroethylene / Q000097:blood; D004781:Environmental Exposure / Q000032:analysis* / Q000706:statistics & numerical data; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D055768:Halogenated Diphenyl Ethers / Q000097:blood; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000097:blood; D008297:Male; D008800:Mexico; D008875:Middle Aged; D011078:Polychlorinated Biphenyls / Q000097:blood; D055815:Young Adult
chemical_list: D004785:Environmental Pollutants; D055768:Halogenated Diphenyl Ethers; D006843:Hydrocarbons, Chlorinated; D003633:Dichlorodiphenyl Dichloroethylene; D003634:DDT; D011078:Polychlorinated Biphenyls
keywords: Biomonitoring; Mexico; PBDEs; PCBs; POPs; p,p′-DDE