title: Role of NF-κB-dependent signaling in the realization of growth potential of mesenchymal progenitor cells in vitro.
abstract: Signal pathways of realization of growth potential of mesenchymal progenitor cells related to transcription factor NF-κB were studied in vitro. NF-κB was found to participate in the proliferation and differentiation of progenitor elements that can be blocked by its specific inhibitor oridonin. NF-κB inhibitor aurothiomalate had no effect on the functions of fibroblastic CFU.
authors.affiliation: Research Institute of Pharmacology, Siberian Branch of Russian Academy of Medical Sciences, Tomsk, Russia. rgn@pharm.tsu.ru.
authors.forename: G N
authors.initials: GN
authors.lastname: Zyuz'kov
authors.forename: M G
authors.initials: MG
authors.lastname: Danilets
authors.forename: A A
authors.initials: AA
authors.lastname: Ligacheva
authors.forename: V V
authors.initials: VV
authors.lastname: Zhdanov
authors.forename: E V
authors.initials: EV
authors.lastname: Udut
authors.forename: L A
authors.initials: LA
authors.lastname: Miroshnichenko
authors.forename: E V
authors.initials: EV
authors.lastname: Simanina
authors.forename: E S
authors.initials: ES
authors.lastname: Trofimova
authors.forename: M Yu
authors.initials: MY
authors.lastname: Minakova
authors.forename: A V
authors.initials: AV
authors.lastname: Chaikovskii
authors.forename: V I
authors.initials: VI
authors.lastname: Agafonov
authors.forename: A M
authors.initials: AM
authors.lastname: Dygai
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D049109:Cell Proliferation; D002478:Cells, Cultured; D008297:Male; D059630:Mesenchymal Stem Cells / Q000502:physiology*; D051379:Mice; D008808:Mice, Inbred CBA; D016328:NF-kappa B / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D016328:NF-kappa B