title: Transcription factors for dental stem cell differentiation.
abstract: Dental stem cells are excellent for oral and craniofacial tissue engineering. A profound knowledge about molecular processes in dental stem cells is necessary to create treatment approaches in oral medicine. Transcription factors regulate gene expression and provide decisive information for cellular functions. In recent years, the authors have investigated transcriptomes in dental stem cells before and after osteogenic differentiation. The present paper reports on the potential role of selected transcription factors, including ZBTB16, TP53, and SP1, in dental stem cell differentiation. This review discusses putative molecular processes in dental stem cells and summarizes the current knowledge.
authors.forename: Sandra
authors.initials: S
authors.lastname: Viale-Bouroncle
authors.forename: Oliver
authors.initials: O
authors.lastname: Felthaus
authors.forename: Gottfried
authors.initials: G
authors.lastname: Schmalz
authors.forename: Torsten E
authors.initials: TE
authors.lastname: Reichert
authors.forename: Christian
authors.initials: C
authors.lastname: Morsczeck
mesh_terms: D002454:Cell Differentiation / Q000235:genetics / Q000502:physiology*; D003782:Dental Pulp / Q000166:cytology; D003795:Dental Sac / Q000166:cytology; D006801:Humans; D051741:Kruppel-Like Transcription Factors / Q000235:genetics / Q000502:physiology; D009805:Odontogenesis / Q000235:genetics*; D010012:Osteogenesis / Q000235:genetics / Q000502:physiology; D010513:Periodontal Ligament / Q000166:cytology; D000075722:Promyelocytic Leukemia Zinc Finger Protein; D016329:Sp1 Transcription Factor / Q000235:genetics / Q000502:physiology; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology; D023822:Tissue Engineering; D019227:Tooth Apex / Q000166:cytology; D014094:Tooth, Deciduous / Q000166:cytology; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology*; D014158:Transcription, Genetic / Q000502:physiology; D016159:Tumor Suppressor Protein p53 / Q000235:genetics / Q000502:physiology
chemical_list: D051741:Kruppel-Like Transcription Factors; D000075722:Promyelocytic Leukemia Zinc Finger Protein; D016329:Sp1 Transcription Factor; C495901:TP53 protein, human; D014157:Transcription Factors; D016159:Tumor Suppressor Protein p53; C092037:ZBTB16 protein, human