title: Ethical and legal issues related to the donation and use of nonstandard organs for transplants.
abstract: Transplantation of nonstandard or expanded criteria donor organs creates several potential ethical and legal problems in terms of consent and liability, and new challenges for research and service development; it highlights the need for a system of organ donation that responds to an evolving ethical landscape and incorporates scientific innovation to meet the needs of recipients, but which also safeguards the interests and autonomy of the donor. In this article, the use of deceased donor organs for transplants that fail to meet standard donor criteria and the legitimacy of interventions and research aimed at optimizing their successful donation are discussed.
authors.affiliation: NIHR Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust, MRC Centre for Transplantation, Guy's Hospital, King's College London, Fifth Floor Tower Wing, London SE1 9RT, UK. Electronic address: antonia.cronin@kcl.ac.uk.
authors.forename: Antonia J
authors.initials: AJ
authors.lastname: Cronin
mesh_terms: D006801:Humans; D016365:Liability, Legal; D009927:Tissue and Organ Procurement / Q000941:ethics* / Q000331:legislation & jurisprudence*
keywords: Donor and donor organ quality; Nonstandard organs for transplant; Organ donation and transplantation; Transplantation-related research