title: High coating of Ru(II) complexes on gold nanoparticles for single particle luminescence imaging in cells.
abstract: Gold nanoparticles are efficiently labelled with a luminescent ruthenium complex, producing 13 and 100 nm diameter, monodisperse red-emissive imaging probes with luminescence lifetimes prolonged over the molecular unit. Single, 100 nm particles are observed in whole cell luminescence imaging which reveals their biomolecular association with chromatin in the nucleus of cancer cells.
authors.affiliation: School of Chemistry, The University of Birmingham, Edgbaston, B15 2TT, UK. z.pikramenou@bham.ac.uk.
authors.forename: Nicola J
authors.initials: NJ
authors.lastname: Rogers
authors.forename: Sunil
authors.initials: S
authors.lastname: Claire
authors.forename: Robert M
authors.initials: RM
authors.lastname: Harris
authors.forename: Shiva
authors.initials: S
authors.lastname: Farabi
authors.forename: Gerald
authors.initials: G
authors.lastname: Zikeli
authors.forename: Iain B
authors.initials: IB
authors.lastname: Styles
authors.forename: Nikolas J
authors.initials: NJ
authors.lastname: Hodges
authors.forename: Zoe
authors.initials: Z
authors.lastname: Pikramenou
mesh_terms: D045744:Cell Line, Tumor; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism*; D006046:Gold / Q000737:chemistry*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D018613:Microscopy, Confocal; D010316:Particle Size; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D056831:Coordination Complexes; D006046:Gold; D012428:Ruthenium