title: Follicular hybrid cyst: a combination of bullous pilomatricoma and epidermoid cyst.
abstract: The follicular hybrid is composed of more than two components of pilosebaceous unit. There are several studies of hybrid cyst, combination of trichilemmal and epidermoid cyst was the most frequently reported. In this paper, we reported one case of hybrid cyst composed of bullous pilomatricoma and epidermoid cyst. A 14-year-old girl was complaint of a solitary flesh-colored to erythematous nodule with flaccid appearance sized 3.2 × 1.8 cm in diameter on her right upper back for one year. The histologic findings showed there were edema and proliferation of capillaries in the superficial dermis, a cyst in the middle to deep dermis. There were laminated keratins in the cystic space. The cyst wall was composed of two different components, one was composed of epithelial cells containing of granular layer, and another consisted of basophilic cells, transient cells and shadow cells. The cyst not related with Gardner's syndrome. Hybrid cyst such as trichilemmal cyst, epidermoid and pilomatricoma cysts maybe have same clinical features or mimicking each others, but we can distinguish them from histopathology evaluation.
authors.affiliation: Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430022, China.
authors.forename: Tutyana
authors.initials: T
authors.lastname: Sanusi
authors.forename: Xiaoying
authors.initials: X
authors.lastname: Qu
authors.forename: Yanqiu
authors.initials: Y
authors.lastname: Li
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.forename: Ming
authors.initials: M
authors.lastname: Wang
authors.forename: Yun
authors.initials: Y
authors.lastname: Zhao
authors.forename: Zhen
authors.initials: Z
authors.lastname: Yang
authors.forename: Xiangjie
authors.initials: X
authors.lastname: An
authors.forename: Yue
authors.initials: Y
authors.lastname: Qian
authors.forename: Chunsen
authors.initials: C
authors.lastname: Wang
authors.forename: Hongxiang
authors.initials: H
authors.lastname: Chen
authors.forename: Siyuan
authors.initials: S
authors.lastname: Chen
authors.forename: Changzheng
authors.initials: C
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D001706:Biopsy; D004814:Epidermal Cyst / Q000473:pathology*; D005260:Female; D005497:Follicular Cyst / Q000473:pathology*; D006201:Hair Diseases / Q000473:pathology*; D006801:Humans; D018296:Pilomatrixoma / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*
keywords: Hybrid cyst; bullous pilomatricoma; epidermoid cyst