title: Perioperative Pain Management for Patients on Chronic Buprenorphine: A Case Report.
abstract: Here we present a patient with a Type I Chiari malformation who was receiving buprenorphine for chronic pain who underwent two separate urogynecologic procedures for removal of vaginal mesh with two different pain management regimens. For the first procedure at an outside hospital, the patient's usual dose of buprenorphine (8 mg sublingual every 8 hours) was continued up through her surgery and then a full opioid receptor agonist was used for postoperative pain management. The patient complained that this resulted in very poor pain control for her in the postoperative period. Prior to her second procedure, which was performed at our institution, buprenorphine was switched to a full opioid agonist (oral hydromorphone 4 mg every 4 to 6 hours, maximum 20 mg per day) for 5 days prior to surgery; postoperative pain was managed with full opioid receptor agonists. The patient again reported suboptimal pain control in spite of substantially increased doses of opioids. This case report highlights the difficulty of perioperative pain management for patients on chronic buprenorphine and emphasizes the need for additional investigation.
authors.affiliation: Department of Anesthesiology and Critical Care, University of Pennsylvania Health System, Hospital of University of Pennsylvania, 3400 Spruce St., Philadelphia, PA 19104, USA.
authors.forename: Sy-Yeu S
authors.initials: SY
authors.lastname: Chern
authors.forename: Rebecca
authors.initials: R
authors.lastname: Isserman
authors.forename: Linda
authors.initials: L
authors.lastname: Chen
authors.forename: Michael
authors.initials: M
authors.lastname: Ashburn
authors.forename: Renyu
authors.initials: R
authors.lastname: Liu