title: Spatial hyperschematia without spatial neglect after insulo-thalamic disconnection.
abstract: Different spatial representations are not stored as a single multipurpose map in the brain. Right brain-damaged patients can show a distortion, a compression of peripersonal and extrapersonal space. Here we report the case of a patient with a right insulo-thalamic disconnection without spatial neglect. The patient, compared with 10 healthy control subjects, showed a constant and reliable increase of her peripersonal and extrapersonal egocentric space representations - that we named spatial hyperschematia - yet left her allocentric space representations intact. This striking dissociation shows that our interactions with the surrounding world are represented and processed modularly in the human brain, depending on their frame of reference.
authors.affiliation: Department of Neurology, University Hospital of Geneva and Faculty of Medicine, University of Geneva, Geneva, Switzerland ; Laboratory for Neurology and Imaging of Cognition, Department of Fundamental Neurosciences, University of Geneva, Geneva, Switzerland.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Saj
authors.forename: Juliane C
authors.initials: JC
authors.lastname: Wilcke
authors.forename: Markus
authors.initials: M
authors.lastname: Gschwind
authors.forename: Héloïse
authors.initials: H
authors.lastname: Emond
authors.forename: Frédéric
authors.initials: F
authors.lastname: Assal
mesh_terms: D000369:Aged, 80 and over; D001921:Brain / Q000473:pathology; D002540:Cerebral Cortex / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging; D009483:Neuropsychological Tests; D010468:Perceptual Disorders / Q000175:diagnosis / Q000503:physiopathology*; D013028:Space Perception; D013788:Thalamus / Q000503:physiopathology*