title: Comparative characteristics of the cytochemical status of peritoneal and alveolar macrophages in the progeny of female rats with experimental liver disease.
abstract: The effects of experimental maternal chronic liver disease (induced by injection of hepatotropic toxin D(+)-galactosamine hydrochloride) on cytochemical activity of peritoneal and alveolar macrophages of the progeny were studied at different stages of postnatal development. Maternal hepatobiliary disease caused a reduction of the functional activity of macrophageal cells in the progeny, which manifested by inhibition of the lysosomal and peroxidase activities and low level of acid phosphatase.
authors.affiliation: Department of Microbiology, Biological Faculty, Chelyabinsk State University, Russia. katya_shavrina@mail.ru.
authors.forename: G V
authors.initials: GV
authors.lastname: Bruykhin
authors.forename: E Yu
authors.initials: EY
authors.lastname: Shavrina
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D000831:Animals, Newborn; D056487:Chemical and Drug Induced Liver Injury, Chronic / Q000378:metabolism / Q000473:pathology*; D005260:Female; D005688:Galactosamine / Q000633:toxicity*; D006651:Histocytochemistry; D008247:Lysosomes / Q000378:metabolism; D016676:Macrophages, Alveolar / Q000378:metabolism / Q000473:pathology*; D017737:Macrophages, Peritoneal / Q000378:metabolism / Q000473:pathology*; D009928:Organ Specificity; D009195:Peroxidase / Q000378:metabolism; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D017208:Rats, Wistar
chemical_list: D005688:Galactosamine; D009195:Peroxidase; D000135:Acid Phosphatase