title: CO-releasing binuclear rhodium complexes as inhibitors of nitric oxide generation in stimulated macrophages.
abstract: Nontoxic CO-releasing dirhodium complexes act as inhibitors of NO in stimulated macrophage cells, suggesting that novel antiinflammatory treatments could involve the use of these types of binuclear complexes.
authors.affiliation: Centro de Reconocimiento Molecular y Desarrollo Tecnológico, Unidad Mixta Universitat Politècnica de Valéncia, Universitat de València , Camino de Vera s/n, 46022 Valencia, Spain.
authors.forename: María E
authors.initials: ME
authors.lastname: Moragues
authors.forename: Rita
authors.initials: R
authors.lastname: Brines
authors.forename: MaCarmen
authors.initials: M
authors.lastname: Terencio
authors.forename: Félix
authors.initials: F
authors.lastname: Sancenón
authors.forename: Ramón
authors.initials: R
authors.lastname: Martínez-Máñez
authors.forename: MaJosé
authors.initials: M
authors.lastname: Alcaraz
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000494:pharmacology*; D001681:Biological Assay; D002248:Carbon Monoxide / Q000737:chemistry / Q000378:metabolism*; D002460:Cell Line; D056831:Coordination Complexes / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D008264:Macrophages / Q000187:drug effects* / Q000378:metabolism; D008954:Models, Biological; D009569:Nitric Oxide / Q000037:antagonists & inhibitors*; D012238:Rhodium / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000893:Anti-Inflammatory Agents; D056831:Coordination Complexes; D009569:Nitric Oxide; D002248:Carbon Monoxide; D012238:Rhodium