title: Viability of stressed Mycobacterium tuberculosis and association with multidrug resistance.
abstract: This study investigated biological characteristics of recovered stressed M. tuberculosis isolates that failed to grow in differential culture media for phenotypic identification and in culture media containing anti-tuberculosis drugs for drug-susceptibility testing, despite of having grown in primary culture. It represents an improvement in the diagnosis of MDR tuberculosis and tuberculosis control.
authors.affiliation: Instituto Adolfo Lutz, São Paulo, SP, Brazil.
authors.forename: Maria Conceição
authors.initials: MC
authors.lastname: Martins
authors.forename: Carmen Maria Saraiva
authors.initials: CM
authors.lastname: Giampaglia
authors.forename: Erica
authors.initials: E
authors.lastname: Chimara
authors.forename: Rosângela Siqueira
authors.initials: RS
authors.lastname: Oliveira
authors.forename: Danielle
authors.initials: D
authors.lastname: Vedovello
authors.forename: Sidnei Miyoshi
authors.initials: SM
authors.lastname: Sakamoto
authors.forename: Lucilaine
authors.initials: L
authors.lastname: Ferrazoli
mesh_terms: D003470:Culture Media / Q000737:chemistry; D024901:Drug Resistance, Multiple, Bacterial; D050296:Microbial Viability; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000254:growth & development / Q000502:physiology*; D013312:Stress, Physiological
chemical_list: D003470:Culture Media
keywords: Mycobacterium; culture growth; multidrug resistance; spoligotyping