title: Glioblastoma multiforme metastastic to the bone: diagnosis by (18)F-NaF PET/CT.
abstract: Extracranial metastases from glioblastoma multiforme (GBM) are rare. We report a case of osseous metastases from GBM diagnosed by F-NaF PET/CT. A 30-year-old man with a history of GBM presented with bone pain and underwent F-NaF PET/CT for further evaluation. On PET/CT, intense uptake in 2 bone lesions was noted. Histopathologic evaluation revealed osseous metastases from GBM. Although rare, bone metastases have to be considered in patients with axial tumors and atraumatic bone pain. F-NaF PET/CT is a highly sensitive and valuable tool for detection of osseous metastases.
authors.affiliation: From the *Department of Diagnostic and Interventional Radiology and †Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
authors.forename: Thorsten
authors.initials: T
authors.lastname: Derlin
authors.forename: Till Sebastian
authors.initials: TS
authors.lastname: Clauditz
authors.forename: Peter
authors.initials: P
authors.lastname: Bannas
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary*; D005462:Fluorine Radioisotopes; D005909:Glioblastoma / Q000473:pathology*; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D012969:Sodium Fluoride; D014057:Tomography, X-Ray Computed
chemical_list: D005462:Fluorine Radioisotopes; D012969:Sodium Fluoride