title: Possible health effects of caffeinated coffee consumption on Alzheimer's disease and cardiovascular disease.
abstract: Coffee has been known to have both beneficial and harmful effects upon health. Coffee is one of the most widely consumed beverages, worldwide. Dementia/Alzheimer's disease (AD) and cardiovascular disease (CVD) are public health problems that are rapidly increasing in the aging population. Due to the high consumption of coffee, even small effects on an individual's health could have a large effect on public health.The aim of this review article is to provide an overview of previously published studies of coffee consumption on health. Herein, we focus on epidemiological and experimental findings to investigate whether coffee-drinking habits, and/or the quantity of coffee consumption, have any relationship to CVD, dementia/AD, and other chronic diseases. Although the underlying mechanisms are not fully understood, when comparing coffee drinkers with non-drinkers, moderate doses of caffeine showed protective effects against CVD and AD. We hypothesized that caffeine may be a novel therapy to treat CVD and dementia/AD.
authors.affiliation: College of Health Sciences, Korea University, Seoul 136-703.
authors.forename: Dong-Chul
authors.initials: DC
authors.lastname: You
authors.forename: Young-Soon
authors.initials: YS
authors.lastname: Kim
authors.forename: Ae-Wha
authors.initials: AW
authors.lastname: Ha
authors.forename: Yu-Na
authors.initials: YN
authors.lastname: Lee
authors.forename: Soo-Min
authors.initials: SM
authors.lastname: Kim
authors.forename: Chun-Heum
authors.initials: CH
authors.lastname: Kim
authors.forename: Seung-Ha
authors.initials: SH
authors.lastname: Lee
authors.forename: Dalwoong
authors.initials: D
authors.lastname: Choi
authors.forename: Jae-Min
authors.initials: JM
authors.lastname: Lee
keywords: Alzheimer;s disease; Caffeine; Cardiovascular disease; Coffee; Dementia