title: Survival of the fattest.
abstract: Experiments on the social amoeba Dictyostelium discoideum show that the origins of lineage bias in this system lie in the nutritional history of individual cells. Clues to the molecular basis for this process suggest similar forces may be at work in early mammalian development.
authors.affiliation: Sophie M Morgani is in the Danish Stem Cell Center (DanStem), University of Copenhagen, Copenhagen, Denmark sophie.morgani@sund.ku.dk.
authors.forename: Sophie M
authors.initials: SM
authors.lastname: Morgani
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Brickman
mesh_terms: D004023:Dictyostelium / Q000166:cytology*; D018631:ras Proteins / Q000378:metabolism*
chemical_list: D018631:ras Proteins
keywords: Cell fate choice; Lineage priming; RAS; Salt and pepper; differentiation; heterogeneous