title: Therapeutic status-dependent thymic changes on 18F-FDG PET/CT in an adult patient with lymphoma who underwent 2 phases of chemotherapy.
abstract: A 31-year-old woman who underwent 2 phases of chemotherapy for Hodgkin lymphoma subsequently underwent 8 F-FDG PET/CT scans for staging and treatment response evaluation. The images revealed that the Hounsfield unit and SUV of the thymus changed with the therapeutic status; both decreased to the lowest level 0.5 months after chemotherapy and increased to the highest level 8 to 12 months after the end of treatment. Interestingly, we found a positive correlation between the thymic Hounsfield unit and SUV, with a Spearman correlation coefficient of 0.946 (P < 0.001).
authors.affiliation: From the Department of Nuclear Medicine, National Key Discipline of Medical Imaging and Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
authors.forename: Qiuping
authors.initials: Q
authors.lastname: Fan
authors.forename: Minggang
authors.initials: M
authors.lastname: Su
authors.forename: Lin
authors.initials: L
authors.lastname: Li
authors.forename: Fanglan
authors.initials: F
authors.lastname: Li
authors.forename: Rong
authors.initials: R
authors.lastname: Tian
mesh_terms: D000328:Adult; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D013950:Thymus Gland; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18