title: Nitrite activation to nitric oxide via one-fold protonation of iron(II)-O,O-nitrito complex: relevance to the nitrite reductase activity of deoxyhemoglobin and deoxyhemerythrin.
abstract: The reversible transformations [(Bim)3Fe(κ(2)-O2N)][BF4] (3) <-> [(Bim)3Fe(NO)(κ(1)-ONO)][BF4]2 (4) were demonstrated and characterized. Transformation of O,O-nitrito-containing complex 3 into [(Bim)3Fe(μ-O)(μ-OAc)Fe(Bim)3](3+) (5) along with the release of NO and H2O triggered by 1 equiv of AcOH implicates that nitrite-to-nitric oxide conversion occurs, in contrast to two protons needed to trigger nitrite reduction producing NO observed in the protonation of [Fe(II)-nitro] complexes.
authors.affiliation: Department of Chemistry and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University , Hsinchu, 30013, Taiwan.
authors.forename: Chih-Chin
authors.initials: CC
authors.lastname: Tsou
authors.forename: Wan-Lin
authors.initials: WL
authors.lastname: Yang
authors.forename: Wen-Feng
authors.initials: WF
authors.lastname: Liaw
mesh_terms: D005296:Ferrous Compounds / Q000737:chemistry*; D006422:Hemerythrin / Q000737:chemistry*; D006454:Hemoglobins / Q000737:chemistry*; D009569:Nitric Oxide / Q000737:chemistry*; D009572:Nitrite Reductases / Q000737:chemistry*; D009573:Nitrites / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods
chemical_list: D005296:Ferrous Compounds; D006422:Hemerythrin; D006454:Hemoglobins; D009573:Nitrites; C043119:deoxyhemerythrin; D009569:Nitric Oxide; C100003:deoxyhemoglobin; D009572:Nitrite Reductases