title: Dengue infection in Dhaka City, Bangladesh.
abstract: Dengue fever (DF) and dengue haemorrhagic fever (DHF) are now endemic in Bangladesh with outbreaks being reported quite frequently. This cross sectional study was done clinically suspected dengue patients were selected from different hospitals of Dhaka city, Bangladesh, from January 2008 to December 2008. The clinical features, risk factors and laboratory findings associated with dengue infection were investigated among 201 clinically suspected patients. Antibodies were detected in 137(68.2%) cases. Of these, 80(58.4%) were primary and 57(41.6%) as secondary dengue cases according to presence of dengue-specific IgM and/or IgG antibodies. Among primary cases, 70(87.5%) were DF and 10(12.5%) were DHF cases, in contrast to secondary cases, where 10(18.1%) were DF and 47(81.9%) were DHF cases. Majority (57.9%) of patients presented with Grade I and 42.1% had Grade II disease. Patients between 16-30 years were the most vulnerable age group (81.3% DF and 71.9% DHF patients). Males out-numbered females with 72.5% male vs. 27.5% female patients having DF and 68.4% male vs. 31.6% female patients having DHF. The monsoon period was the peak season for dengue infection. Headache and arthralgia were the most frequent symptoms in both DF and DHF, but vomiting was more common in DHF. The Tourniquet test was significantly positive among DHF than DF cases (p = 0.001). Platelet count was the only laboratory parameter that showed significantly higher values among DHF than DF cases (p = 0.001).
authors.affiliation: Dr Rabeya Sharmin, Lecturer, Department of Virology, Dhaka Medical College, Dhaka, Bangladesh.
authors.forename: R
authors.initials: R
authors.lastname: Sharmin
authors.forename: S
authors.initials: S
authors.lastname: Tabassum
authors.forename: K Z
authors.initials: KZ
authors.lastname: Mamun
authors.forename: A
authors.initials: A
authors.lastname: Nessa
authors.forename: M
authors.initials: M
authors.lastname: Jahan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood; D001459:Bangladesh / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003715:Dengue / Q000097:blood / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010976:Platelet Count
chemical_list: D000914:Antibodies, Viral