title: Regulatory T cells and B cells: implication on autoimmune diseases.
abstract: The regulatory T (Treg) cells play an important role in the maintenance of homeostasis and the prevention of autoimmune diseases. Although most studies are focusing on the role of Treg cells in T cells and T cells-mediated diseases, these cells also directly affect B cells and other non-T cells. This manuscript updates the role of Treg cells on the B cells and B cell-mediated diseases. In addition, the mechanisms whereby Treg cells suppress B cell responses have been discussed.
authors.affiliation: Division of Liver Transplantation Surgery, The First Affiliated Hospital of Nanjing Medical University 300 Guangzhou Road, Nanjing, 210029, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Wang
authors.forename: Song Guo
authors.initials: SG
authors.lastname: Zheng
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000378:metabolism; D001327:Autoimmune Diseases / Q000276:immunology* / Q000378:metabolism; D015551:Autoimmunity; D060151:B-Lymphocytes, Regulatory / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D015398:Signal Transduction; D050378:T-Lymphocytes, Regulatory / Q000276:immunology* / Q000378:metabolism
chemical_list: D001323:Autoantibodies
keywords: B cells; Foxp3; Treg; antibodies; autoimmune diseases