title: A facile one-pot method to synthesize a polypyrrole/hemin nanocomposite and its application in biosensor, dye removal, and photothermal therapy.
abstract: In this work, we introduced a facile method for the construction of a polypyrrole/hemin (PPy/hemin) nanocomposite via one-pot chemical oxidative polymerization. In this process, a hemin molecule serving as a dopant was entrapped in the PPy nanocomposite during chemical oxidative polymerization. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), and UV-visible spectroscopy results demonstrated that the PPy/hemin nanocomposite was successfully synthesized. The as-prepared nanocomposite exhibited intrinsic peroxidase-like catalytic activities, strong adsorption properties, and an excellent near-infrared (NIR) light-induced thermal effect. We utilized the nanomaterials to catalyze the oxidation of a peroxidase substrate 3,3,5,5-tetramethylbenzidine by H2O2 to the oxidized colored product which provided a colorimetric detection of glucose. As low as 50 μM glucose could be detected with a linear range from 0.05 to 8 mM. Moreover, the obtained nanocomposite also showed excellent removal efficiency for methyl orange and rhodamine B and a photothermal effect, which implied a promising application as the pollutant adsorbent and photothermal agent. The unique nature of the PPy/hemin nanocomposite makes it very promising for the fabrication of inexpensive, high-performance bioelectronic devices in the future.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science , Changchun, Jilin, 130022, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Hu
authors.forename: Lei
authors.initials: L
authors.lastname: Han
authors.forename: Shaojun
authors.initials: S
authors.lastname: Dong
mesh_terms: D000327:Adsorption; D015374:Biosensing Techniques; D004396:Coloring Agents / Q000302:isolation & purification*; D005947:Glucose / Q000032:analysis; D006427:Hemin / Q000138:chemical synthesis*; D006979:Hyperthermia, Induced; D008854:Microscopy, Electron / Q000379:methods; D053761:Nanocomposites; D010789:Phototherapy; D011108:Polymers / Q000138:chemical synthesis*; D011758:Pyrroles / Q000138:chemical synthesis*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D004396:Coloring Agents; D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole; D006427:Hemin; D005947:Glucose