title: New cytotoxic apotirucallanes from the leaves of Walsura trichostemon.
abstract: Three new apotirucallanes (1-3) were isolated from the leaves of Walsura trichostemon. Their structures were identified by interpretation of their spectroscopic data as well as comparison with those reported in the literature. In addition, all isolated compounds were evaluated for their cytotoxicity against KB and HeLa cells.
authors.affiliation: Natural Products Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
authors.forename: Jirapast
authors.initials: J
authors.lastname: Sichaem
authors.forename: Suttira
authors.initials: S
authors.lastname: Khumkratok
authors.forename: Pongpan
authors.initials: P
authors.lastname: Siripong
authors.forename: Santi
authors.initials: S
authors.lastname: Tip-pyang
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry* / Q000633:toxicity; D045744:Cell Line, Tumor; D006367:HeLa Cells; D006801:Humans; D029582:Meliaceae / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry* / Q000633:toxicity
chemical_list: C000590638:11,25-dideacetyltrichostemonate; C000590723:21,24,25-triacetyl-7-deacetyl-6-hydroxylbrujavanone E; C000590640:7-deacetylbrujavanone E; D000970:Antineoplastic Agents; D014315:Triterpenes; C514394:apotirucallane