title: Methotrexate: new uses for an old drug.
authors.affiliation: Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel. Electronic address: hashkesp@szmc.org.il.
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Hashkes
authors.affiliation: Division of Pediatric Rheumatology, Children's Mercy Hospitals and Clinics, Kansas City, MO.
authors.forename: Mara L
authors.initials: ML
authors.lastname: Becker
authors.affiliation: Division of Rheumatology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
authors.forename: David A
authors.initials: DA
authors.lastname: Cabral
authors.affiliation: Division of Rheumatology, The Hospital for Sick Children, Departments of Pediatrics and Medicine, University of Toronto, Toronto, ON, Canada.
authors.forename: Ronald M
authors.initials: RM
authors.lastname: Laxer
authors.affiliation: Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL.
authors.forename: Amy S
authors.initials: AS
authors.lastname: Paller
authors.affiliation: Division of Pediatric Rheumatology, Duke University, Durham, NC.
authors.forename: C Egla
authors.initials: CE
authors.lastname: Rabinovich
authors.affiliation: Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel.
authors.forename: Dan
authors.initials: D
authors.lastname: Turner
authors.affiliation: Department of Pediatrics, University of Padua, Padua, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Zulian
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000188:drug therapy*; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D018501:Antirheumatic Agents; D008727:Methotrexate
keywords: AICAR; Amino-imidazole carboxamide ribonucleotide; CD; Crohn's disease; GPA; Granulomatosis with polyangiitis; IBD; Inflammatory bowel disease; JIA; Juvenile idiopathic arthritis; MRP; MTX; Methotrexate; Myeloid-related protein; SNP; Single nucleotide polymorphism