title: Monitoring Patient Improvement Parameters following Pasireotide Treatment in Cushing's Disease.
abstract: Cushing's disease (CD) is a disorder in which chronic excess adrenocorticotropic hormone production is associated with multiple comorbidities and diminished quality of life. Postsurgical monitoring is important, and newer therapies are available for the management of surgical failure or disease recurrence. In this clinical case, we illustrate the importance of the nursing role in long-term management of CD, particularly as nurses may be the first point of contact for patients with CD. Alertness to disease signs and symptoms is crucial for timely diagnosis and improved outcomes. Successful therapy for CD requires careful monitoring of hormonal control, metabolic parameters, and therapy complications. Ongoing management requires lifelong monitoring of metabolic parameters, of side effects of treatment, and of signs of disease recurrence. Appropriate referrals may be required to facilitate overall outcomes and patient wellbeing. This patient was enrolled in a Phase III trial that was registered in the USA with clinicaltrial.gov.
authors.affiliation: Northwest Pituitary Center, 3303 SW Bond Avenue, Portland, OR 97239, USA ; Department of Neurosurgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
authors.forename: Chris
authors.initials: C
authors.lastname: Yedinak
authors.forename: Jessica
authors.initials: J
authors.lastname: Brzana
authors.forename: Maria
authors.initials: M
authors.lastname: Fleseriu