title: Bovine response to lipoarabinomannan vaccination and challenge with Mycobacterium paratuberculosis.
abstract: This study aimed to evaluate the immune response in bovines following immunization with a mycobaterial Lipoarabinomannan extract (LAMe) and the effect of Map challenge. LAMe vaccine induced specific antibody levels that diminished after the challenge and affected Map excretion at least for 100 days thereafter.
authors.affiliation: Cátedra de Inmunología, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Ana
authors.initials: A
authors.lastname: Jolly
authors.forename: Claudia
authors.initials: C
authors.lastname: Morsella
authors.forename: Laura
authors.initials: L
authors.lastname: Bass
authors.forename: María Andrea
authors.initials: MA
authors.lastname: Fiorentino
authors.forename: Fernando Alberto
authors.initials: FA
authors.lastname: Paolicchi
authors.forename: Silvia Leonor
authors.initials: SL
authors.lastname: Mundo
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000276:immunology*; D002417:Cattle; D004797:Enzyme-Linked Immunosorbent Assay; D008070:Lipopolysaccharides / Q000008:administration & dosage / Q000276:immunology* / Q000302:isolation & purification; D016927:Mycobacterium avium subsp. paratuberculosis / Q000276:immunology*; D010283:Paratuberculosis / Q000276:immunology / Q000517:prevention & control*; D014611:Vaccination / Q000379:methods*
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D008070:Lipopolysaccharides; C050016:lipoarabinomannan
keywords: LAM; bovine; experimental challenge; humoral immune response; paratuberculosis