title: Tuning, inhibiting and restoring the enzyme mimetic activities of Pt-apoferritin.
abstract: A selective and specific inhibition of the catalase mimetic activity but not SOD-like activity of Pt-apoferritin can be achieved through the choice of the inhibitor. The recovery of activity using a reducing agent was explored and proven to successfully restore the surface-chemistry of NPs.
authors.affiliation: CIC nanoGUNE, Tolosa Hiribidea 76, 20018 Donostia-San Sebastian, Spain. l.zhang@nanogune.eu m.knez@nanogune.eu.
authors.forename: Unai
authors.initials: U
authors.lastname: Carmona
authors.forename: Lianbing
authors.initials: L
authors.lastname: Zhang
authors.forename: Le
authors.initials: L
authors.lastname: Li
authors.forename: Wolfram
authors.initials: W
authors.lastname: Münchgesang
authors.forename: Eckhard
authors.initials: E
authors.lastname: Pippel
authors.forename: Mato
authors.initials: M
authors.lastname: Knez
mesh_terms: D001052:Apoferritins / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism*; D032701:Biomimetics; D004789:Enzyme Activation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006861:Hydrogen Peroxide / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry; D010984:Platinum / Q000737:chemistry*; D019163:Reducing Agents / Q000737:chemistry; D013499:Surface Properties
chemical_list: D004791:Enzyme Inhibitors; D019163:Reducing Agents; D010984:Platinum; D001052:Apoferritins; D006861:Hydrogen Peroxide