title: Comparison of Locoregional Recurrence with Mastectomy vs. Breast Conserving Surgery in Pregnancy Associated Breast Cancer (PABC).
abstract: We have compared outcomes, including the locoregional recurrence, between mastectomy and breast conserving therapy in PABC. Patients were divided into those who were treated with mastectomies (group 1) and those with breast conserving surgery (group 2). The groups were comparable except for lower mean age in group 2 and more patients with stage III disease and higher number of nodes positive in the group 1. Five-year actuarial LRR, distant metastases free survival and overall survival in group 1 vs. 2 were 10% vs. 37%, 73% vs. 81% and 57% vs. 59% respectively. The patients with PABC treated with breast conserving therapy, despite having lower stage disease, have a higher risk of local regional recurrence in comparison with those treated with mastectomy.
authors.affiliation: Department of Radiation Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA. beriwals@upmc.edu.
authors.forename: Sushil
authors.initials: S
authors.lastname: Beriwal
authors.forename: Bunja
authors.initials: B
authors.lastname: Rungruang
authors.forename: Atilla
authors.initials: A
authors.lastname: Soran
authors.forename: Darcy
authors.initials: D
authors.lastname: Thull
authors.forename: Joseph L
authors.initials: JL
authors.lastname: Kelley
authors.forename: Rohit
authors.initials: R
authors.lastname: Bhargava
authors.forename: Chyongchiou J
authors.initials: CJ
authors.lastname: Lin
authors.forename: Paniti
authors.initials: P
authors.lastname: Sukumvanich