title: Analysis of resected gastric cancer in Turkish population.
abstract: OBJECTIVE
  Gastric cancer is still an important health issue in Eastern Europe and Middle East, including Turkey, although its prevalence is decreasing in the western world.
  
  
  METHODS
  In order to define the profiles of the patients operated with a diagnosis of gastric cancer in Turkey, a multicenter retrospective study was conducted.
  
  
  RESULTS
  Six hundred and forty-eight of the 840 patients with complete data in all parameters were included in the analysis. The median follow-up time was 17.16 months (range, 6-143.63 months). Mean age was 57±11.7 (19-85). There was a recurrent disease in 42% of the tumors located at cardia, corpus or antrum, and 86% of diffuse tumors (p<0.0001). The ratio of patients with recurrent disease was greater in stage III and IV tumors (52%) than stage II (29%) and stage I (17%) tumors. There were also greater recurrence ratios in patients with node positive (pN1-3) patients than pN0 tumors, and pT3-4 tumors than pT1 or pT2 tumors. Any recurrence was found in 48% of the tumors with lymphovascular invasion, while in 39% without lymphovascular invasion (p=0.026). A statistically significant difference was found in the recurrence status of patients with positive / dissected node ratio of <10% and ≥10% (p<0.0001).
  
  
  CONCLUSIONS
  Gastric cancer cases in Turkey are seen at a younger age, and at a higher stage. Proximal gastric cancer is seen much less than the western series. Prognostic significance of lymphovascular invasion in both univariate, and multivariate analyses is noteworthy.
authors.forename: Gokhan
authors.initials: G
authors.lastname: Demir
authors.forename: Diclehan
authors.initials: D
authors.lastname: Unsal
authors.forename: Nurullah
authors.initials: N
authors.lastname: Zengin
authors.forename: Özlem
authors.initials: Ö
authors.lastname: Er
authors.forename: Faysal
authors.initials: F
authors.lastname: Dane
authors.forename: Şuayib
authors.initials: Ş
authors.lastname: Yalçin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*; D014421:Turkey