title: The choroid plexus: a comprehensive review of its history, anatomy, function, histology, embryology, and surgical considerations.
abstract: BACKGROUND
  The role of the choroid plexus in cerebrospinal fluid production has been identified for more than a century. Over the years, more intensive studies of this structure has lead to a better understanding of the functions, including brain immunity, protection, absorption, and many others. Here, we review the macro- and microanatomical structure of the choroid plexus in addition to its function and embryology.
  
  
  METHODS
  The literature was searched for articles and textbooks for data related to the history, anatomy, physiology, histology, embryology, potential functions, and surgical implications of the choroid plexus. All were gathered and summarized comprehensively.
  
  
  CONCLUSIONS
  We summarize the literature regarding the choroid plexus and its surgical implications.
authors.affiliation: Department of Neurological Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Martin M
authors.initials: MM
authors.lastname: Mortazavi
authors.forename: Christoph J
authors.initials: CJ
authors.lastname: Griessenauer
authors.forename: Nimer
authors.initials: N
authors.lastname: Adeeb
authors.forename: Aman
authors.initials: A
authors.lastname: Deep
authors.forename: Reza
authors.initials: R
authors.lastname: Bavarsad Shahripour
authors.forename: Reza Bavarsad
authors.initials: RB
authors.lastname: Shahripour
authors.forename: Marios
authors.initials: M
authors.lastname: Loukas
authors.forename: Richard Isaiah
authors.initials: RI
authors.lastname: Tubbs
authors.forename: R Shane
authors.initials: RS
authors.lastname: Tubbs
mesh_terms: D002831:Choroid Plexus / Q000033:anatomy & histology* / Q000502:physiology* / Q000601:surgery; D006801:Humans