title: Alzheimer disease: current concepts & future directions.
abstract: Alzheimer disease (AD) is the most common cause of dementia in individuals over age 65, and is expected to cause a major public health crisis as the number of older Americans rapidly expands in the next three decades. Herein, we review current strategies for diagnosis and management of AD, and discuss ongoing clinical research and future therapeutic directions in the battle against this devastating disease.
authors.affiliation: Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, USA. musieke@neuro.wustl.edu
authors.forename: Erik S
authors.initials: ES
authors.lastname: Musiek
authors.forename: Suzanne E
authors.initials: SE
authors.lastname: Schindler
mesh_terms: D000544:Alzheimer Disease / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D003952:Diagnostic Imaging / Q000379:methods*; D019468:Disease Management; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D009017:Morbidity / Q000639:trends; D017410:Practice Guidelines as Topic; D014481:United States / Q000453:epidemiology