title: [Anti-N-methyl-D-aspartic acid receptor encephalitis: clinical analysis of 7 cases].
abstract: OBJECTIVE
  To summarize the clinical manifestations, immunotherapeutic response and prognosis of anti-N-methyl-D-aspartic acid (NMDA) receptor encephalitis.
  
  
  METHODS
  We analyzed the clinical features, tumor markers, serum/cerebrospinal fluid (CSF) antibodies of seven cases with anti-NMDA receptor encephalitis. And the prognosis of different treatments was observed.
  
  
  RESULTS
  Seven patients presented with significant psychiatric symptoms, memory loss, epilepsy, movement disorders and decrease consciousness. And some patients required assisted ventilation because of dysautonomia. All electroencephalography showed slow wave activity without epileptic form discharges. Magnetic resonance imaging was normal or showed T2W and Flair-phase high signal in limbic system, cortex, thalamus. And CSF and serum anti-NMDA receptor antibodies were positive (n = 6).
  
  
  CONCLUSIONS
  Anti-NMDA receptor encephalitis is a kind of fatal but treatable condition. And timely diagnosis and treatment may yield a favorable prognosis.
authors.affiliation: Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Song
authors.forename: Ai-hua
authors.initials: AH
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000097:blood / Q000134:cerebrospinal fluid; D005260:Female; D006801:Humans; D020363:Limbic Encephalitis / Q000175:diagnosis / Q000628:therapy; D008297:Male; D016194:Receptors, N-Methyl-D-Aspartate / Q000276:immunology*; D055815:Young Adult
chemical_list: D000906:Antibodies; D016194:Receptors, N-Methyl-D-Aspartate