title: Mycobacterium shinjukuense lung disease that was successfully treated with antituberculous drugs.
abstract: An 80-year-old woman was referred to our hospital due to a persistent productive cough. Acid-fast staining and a commercial Mycobacterium tuberculosis identification kit with TRC (TRC kit) were positive. However, a false-positive result on the TRC kit was suspected because Mycobacterium tuberculosis was not detected in the sputum culture. Finally, Mycobacterium shinjukuense was detected in an analysis of the rpoB and hsp65 gene sequences. As the diagnostic criteria proposed by the American Thoracic Society were met, a diagnosis of Mycobacterium shinjukuense lung disease was made. Following treatment with isoniazid, rifampicin and ethambutol with drug susceptibility, the patient's acid-fast culture became negative, and the areas of opacity improved.
authors.affiliation: Respiratory Disease Center, Yokohama City University Medical Center, Japan.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Watanabe
authors.forename: Masaharu
authors.initials: M
authors.lastname: Shinkai
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Yamaguchi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Shinoda
authors.forename: Yu
authors.initials: Y
authors.lastname: Hara
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Ishigatsubo
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kaneko
mesh_terms: D000369:Aged, 80 and over; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001426:Bacterial Proteins / Q000235:genetics; D018834:Chaperonin 60 / Q000235:genetics; D005260:Female; D005798:Genes, Bacterial; D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy* / Q000382:microbiology; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy* / Q000382:microbiology; D009170:Nontuberculous Mycobacteria / Q000235:genetics / Q000302:isolation & purification
chemical_list: D000995:Antitubercular Agents; D001426:Bacterial Proteins; D018834:Chaperonin 60; C074119:heat-shock protein 65, Mycobacterium