title: Genetic analysis in a family affected by sick sinus syndrome may reduce the sudden death risk in a young aspiring competitive athlete.
authors.affiliation: CEINGE-Biotecnologie Avanzate s.c.ar.l., Naples, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Detta
authors.affiliation: CEINGE-Biotecnologie Avanzate s.c.ar.l., Naples, Italy; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Naples, Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: Frisso
authors.affiliation: Unità Operativa Clinica di Cardiologia, Ospedale dei Colli, Seconda Università di Napoli, Naples, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Limongelli
authors.affiliation: Medicina dello Sport, Dipartimento di Scienze Biomediche Avanzate, University of Naples Federico II, Naples, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Marzullo
authors.affiliation: Unità Operativa Clinica di Cardiologia, Ospedale dei Colli, Seconda Università di Napoli, Naples, Italy.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Calabrò
authors.affiliation: CEINGE-Biotecnologie Avanzate s.c.ar.l., Naples, Italy; IRCCS-Fondazione SDN, Naples, Italy. Electronic address: salvator@unina.it.
authors.forename: Francesco
authors.initials: F
authors.lastname: Salvatore
mesh_terms: D000328:Adult; D056352:Athletes; D001919:Bradycardia / Q000453:epidemiology / Q000235:genetics; D002648:Child; D016757:Death, Sudden, Cardiac / Q000453:epidemiology*; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D062554:NAV1.5 Voltage-Gated Sodium Channel / Q000235:genetics*; D010375:Pedigree; D012307:Risk Factors; D012804:Sick Sinus Syndrome / Q000453:epidemiology* / Q000235:genetics*
chemical_list: D062554:NAV1.5 Voltage-Gated Sodium Channel; C568320:SCN5A protein, human
keywords: Athletes' sudden death risk; Electrophysiological cell measurements; Genetic analysis of SSS; Mutation functional analysis; Sick sinus syndrome; Sudden death prevention