title: Management of the ACC/AHA Stage D patient: mechanical circulatory support.
abstract: From humble beginnings in 1963 with a single desperately ill patient, mechanical circulatory support has expanded exponentially to where it is a viable alternative for advanced heart failure patients. Some of these patients are awaiting transplant but others will have a mechanical heart pump as their ultimate treatment. The history of MCS devices is reviewed, along with the 4 trials that define the modern era of circulatory support. The practical aspects of life with an MCS device are reviewed and common problems encountered with MCS devices. Future trends including miniaturization and development of completely contained MCS systems are reviewed.
authors.affiliation: Heart Failure and Transplant Research, Newark Beth Israel Medical Center, 201 Lyons Avenue, L-4, Transplant Center, Newark, NJ 07112, USA; Rutgers New Jersey Medical School, Newark, NJ 07103, USA. Electronic address: dbaran@barnabashealth.org.
authors.forename: David A
authors.initials: DA
authors.lastname: Baran
authors.forename: Abhishek
authors.initials: A
authors.lastname: Jaiswal
mesh_terms: D000203:Activities of Daily Living; D000925:Anticoagulants / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D006333:Heart Failure / Q000401:mortality / Q000628:therapy*; D006353:Heart-Assist Devices; D006801:Humans; D011475:Prosthesis Failure; D012648:Self Care; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants
keywords: Advanced heart failure; Device malfunction; Mechanical circulatory support