title: The effect of insert conformity and material on total knee replacement wear.
abstract: The mean average life is increasing; therefore, there is a need to increase the lifetime of the prostheses. To fulfil this requirement, new prosthetic designs and materials are being introduced. Two of the design parameters that may affect wear of total knee replacements, and hence the expected lifetime, are the insert conformity and material. Computational models have been used extensively for wear prediction and optimisation of artificial knee designs. The objective of the present study was to use a previously validated non-dimensional wear coefficient-based computational wear model to investigate the effect of insert conformity and material on the predicted wear in total knee replacements. Four different inserts (curved, lipped, partial flat and custom flat), with different conformity levels, were tested against the same femoral and under two different kinematic inputs (intermediate and high), with different levels of cross-shear. The insert bearing materials were either conventional or moderately cross-linked ultra-high molecular weight polyethylene (UHMWPE). Wear predictions were validated against the experimental data from Leeds knee simulation tests. The predicted wear rates for the curved insert (most conformed) were more than three times those for the flat insert (least conformed). In addition, the computationally predicted average volumetric wear rates for moderately cross-linked UHMWPE bearings were less than half of their corresponding conventional UHMWPE bearings. Moreover, the wear of the moderately cross-linked UHMWPE was shown to be less dependent on the degree of cross-shear, compared to conventional UHMWPE. These results along with supporting experimental studies provide insight into the design variables, which may reduce wear in knee replacements.
authors.affiliation: Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Leeds, UK.
authors.forename: Abdellatif
authors.initials: A
authors.lastname: Abdelgaied
authors.forename: Claire L
authors.initials: CL
authors.lastname: Brockett
authors.forename: Feng
authors.initials: F
authors.lastname: Liu
authors.forename: Louise M
authors.initials: LM
authors.lastname: Jennings
authors.forename: Zhongmin
authors.initials: Z
authors.lastname: Jin
authors.forename: John
authors.initials: J
authors.lastname: Fisher
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation*; D001696:Biomechanical Phenomena; D003198:Computer Simulation; D006801:Humans; D007720:Knee Prosthesis; D008422:Materials Testing; D008954:Models, Biological; D011095:Polyethylenes; D011474:Prosthesis Design
chemical_list: D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene
keywords: Total knee replacements; conventional ultra-high molecular weight polyethylene; insert conformity; moderately cross-linked ultra-high molecular weight polyethylene; wear