title: Model for regulation of VAMP721/722-mediated secretion: growth vs. stress responses.
abstract: The PEN1-SNAP33-VAMP721/722 exocytic pathway is a conserved immunity-associated secretory pathway between monocotyledonous barley and dicotyledonous Arabidopsis plants. In Arabidopsis, this secretory pathway plays an additional role in plant growth and development. However, how this pathway can be manipulated to engage in both growth/development and immunity remains to be answered. To understand its regulation, we recently analyzed the expression of VAMP721/722 genes whose products drive secretory vesicles to the target plasma membrane. By investigating their transcript and protein levels, we found that plants distinctly control the activity of this secretory pathway during biotic or abiotic stress responses. Since stress responses are in general accompanied by growth inhibition in plants and since plants in nature are simultaneously threatened by a number of environmental stresses, understanding of this growth/immunity-related secretory pathway would help to generate more efficiently growth/immunity-balancing plants.
authors.affiliation: Biological Sciences Major; College of Biological Science and Biotechnology; Konkuk University; Seoul, Korea.
authors.forename: Hye
authors.initials: H
authors.lastname: Sup Yun
authors.affiliation: Department of Molecular Biology; Dankook University; Yongin, Korea.
authors.forename: Changhyun
authors.initials: C
authors.lastname: Yi
authors.affiliation: Department of Molecular Biology; Dankook University; Yongin, Korea.
authors.forename: Hyeokjin
authors.initials: H
authors.lastname: Kwon
authors.affiliation: Department of Molecular Biology; Dankook University; Yongin, Korea.
authors.forename: Chian
authors.initials: C
authors.lastname: Kwon
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000254:growth & development*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant; D008954:Models, Biological; D063245:Plant Development / Q000235:genetics; D057865:Plant Immunity / Q000235:genetics; D050683:R-SNARE Proteins / Q000235:genetics / Q000378:metabolism*; D013312:Stress, Physiological / Q000235:genetics
chemical_list: D029681:Arabidopsis Proteins; D050683:R-SNARE Proteins; C570049:VAMP721 protein, Arabidopsis; C570050:VAMP722 protein, Arabidopsis
keywords: VAMP721/722; exocytosis; plant growth; plant immunity; secretory pathway