title: Laryngeal leiomyosarcoma, a case report and review of articles.
abstract: BACKGROUND
  Laryngeal leiomysarcoma is an extremely rare malignancy originating from smooth muscle cells. Its rarity is due to the fact that only less than 50 cases of pure laryngeal leiomyosarcoma and less than 10 cases of hypopharyngeal leiomyosarcaoma have been reported in modern medical literature. Even though the clinical presentation mimics that of a laryngeal carcinoma forming the major bulk of the laryngeal malignancies, the difference in management, warrants an accurate diagnosis.
  
  
  METHODS
  We reported a case of this very rare malignancy presenting in the supraglottic region by highlighting the clinical features, histological and radiological diagnosis and management of this extremely rare malignant entity.
  
  
  CONCLUSIONS
  An accurate histological diagnosis may be difficult; but supplementing by electron microscopy and immunohistochemical staining, the diagnosis can be reached certainly.
authors.affiliation: Department of Otorhinolarngology, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Ehsan
authors.initials: E
authors.lastname: Khadivi
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Taziky
authors.forename: Amir Hossein
authors.initials: AH
authors.lastname: Jafarian
authors.forename: Msoud
authors.initials: M
authors.lastname: Nasseri Sadr
keywords: Larynx; Leiomyosarcoma; Mesodermal neoplasms