title: Intra-articular hyaluronic acid injection: not for gonarthrosis.
abstract: A meta-analysis of 89 randomised trials suggests that, at best, intraarticular hyaluronic acid injection only provides a small relief to patients with osteoarthritis of the knee, but that it can provoke both local reactions and serious adverse effects.
mesh_terms: D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000009:adverse effects*; D007270:Injections, Intra-Articular; D020370:Osteoarthritis, Knee / Q000188:drug therapy*; D016032:Randomized Controlled Trials as Topic; D055675:Viscosupplements / Q000009:adverse effects*
chemical_list: D055675:Viscosupplements; D006820:Hyaluronic Acid