title: No genotoxic effect in exfoliated bladder cells of rat under the exposure of 1800 and 2100 MHz radio frequency radiation.
abstract: In this study, we aimed to investigate the effects of 1800 and 2100 MHz Radio Frequency (RF) radiation on the number of micronucleus (MN) in exfoliated bladder cells of rat which shows the genotoxic damage. Exposure period was 30 min/day, 6 days/week for a month and two months exposure periods. Thirty male wistar albino rats were used for five groups: Group I (n = 6): 1800 MHz RF exposed animals for one month, Group II (n = 6): 2100 MHz RF exposed animals for one month, Group III (n = 6): 2100 MHz RF exposed for two months, Group IV (n = 6): control group for one month, Group V (n = 6): control group for two months. Rats of the control groups were housed in their home cages during the entire experimental period without subjecting to any experimental manipulation. 1800 and 2100 MHz RF exposures did not result in any significant MN frequencies in rat bladder cells with respect to the control groups (p > 0.05). There was no statistically significant difference between 2100 MHz RF exposed groups, either. Further studies are needed to demonstrate if there is any genotoxic effect, micronucleus formation in other tissues of rats.
authors.affiliation: Laboratory Animal Breeding & Experimental Research Center .
authors.forename: N
authors.initials: N
authors.lastname: Gurbuz
authors.forename: B
authors.initials: B
authors.lastname: Sirav
authors.forename: M
authors.initials: M
authors.lastname: Colbay
authors.forename: I
authors.initials: I
authors.lastname: Yetkin
authors.forename: N
authors.initials: N
authors.lastname: Seyhan
mesh_terms: D000818:Animals; D004249:DNA Damage; D008297:Male; D015162:Micronucleus Tests; D011846:Radio Waves / Q000009:adverse effects*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D001743:Urinary Bladder / Q000166:cytology* / Q000378:metabolism / Q000528:radiation effects
keywords: Radio frequency radiation; micronucleus; rats