title: Cellphone-based devices for bioanalytical sciences.
abstract: During the last decade, there has been a rapidly growing trend toward the use of cellphone-based devices (CBDs) in bioanalytical sciences. For example, they have been used for digital microscopy, cytometry, read-out of immunoassays and lateral flow tests, electrochemical and surface plasmon resonance based bio-sensing, colorimetric detection and healthcare monitoring, among others. Cellphone can be considered as one of the most prospective devices for the development of next-generation point-of-care (POC) diagnostics platforms, enabling mobile healthcare delivery and personalized medicine. With more than 6.5 billion cellphone subscribers worldwide and approximately 1.6 billion new devices being sold each year, cellphone technology is also creating new business and research opportunities. Many cellphone-based devices, such as those targeted for diabetic management, weight management, monitoring of blood pressure and pulse rate, have already become commercially-available in recent years. In addition to such monitoring platforms, several other CBDs are also being introduced, targeting e.g., microscopic imaging and sensing applications for medical diagnostics using novel computational algorithms and components already embedded on cellphones. This report aims to review these recent developments in CBDs for bioanalytical sciences along with some of the challenges involved and the future opportunities.
authors.affiliation: HSG-IMIT - Institut für Mikro- und Informationstechnik, Georges-Koehler-Allee 103, 79110, Freiburg, Germany.
authors.forename: Sandeep Kumar
authors.initials: SK
authors.lastname: Vashist
authors.forename: Onur
authors.initials: O
authors.lastname: Mudanyali
authors.forename: E Marion
authors.initials: EM
authors.lastname: Schneider
authors.forename: Roland
authors.initials: R
authors.lastname: Zengerle
authors.forename: Aydogan
authors.initials: A
authors.lastname: Ozcan
mesh_terms: D000465:Algorithms; D015374:Biosensing Techniques; D040421:Cell Phone; D002623:Chemistry Techniques, Analytical; D003124:Colorimetry; D003955:Diagnostic Tests, Routine; D004563:Electrochemistry; D004867:Equipment Design; D005434:Flow Cytometry; D006801:Humans; D007118:Immunoassay; D008853:Microscopy; D018670:Monitoring, Ambulatory; D020349:Surface Plasmon Resonance