title: Comparison of lipid accumulation product with body mass index as an indicator of hypertension risk among Mongolians in China.
abstract: OBJECTIVE
  To compare associations of lipid accumulation product (LAP) and body mass index (BMI) with risk of hypertension.
  
  
  METHODS
  Demographic characteristics, blood pressure and body measurements were obtained, blood lipids and fast plasma glucose were examined, BMI and LAP were calculated for 2589 Mongolians. Multiple linear model and covariance analysis was used to analyze the relationship between LAP and blood pressure levels, multivariate logistic analysis was used to analyze the association between BMI and LAP and hypertension.
  
  
  RESULTS
  LAP and BMI were all significantly higher in hypertensives than in normotensives in both genders. Multivariate adjusted mean levels of SBP and DBP increased with increased LAP and there was a linear association between LAP and blood pressure. LAP had a stronger association with risk of hypertension compared with BMI, linear trend between LAP and risks of hypertension was better than that between BMI and risks of hypertension in males. Compared to the first quartile, the odds ratios [95% confidence intervals (95% CIs)] of hypertension associated with the second, third and fourth quartiles of LAP were 1.85(1.23,2.79), 2.20(1.47,3.28), 4.21(2.78,6.38) in males; compared to the first quartile, the odds ratios (95% CIs) of hypertension associated with the second, third and fourth quartiles of BMI were 0.93(0.62,1.38), 1.23(0.83,1.84), 2.80(1.86,4.21) in males.
  
  
  CONCLUSIONS
  LAP was more closely associated with risk of hypertension than BMI in Mongolian males, this study suggested that LAP might be a preferred anthropometry measurement to predict risk of hypertension in males. Future prospective cohort studies should be conducted to test the causal relationship between LAP and the risk of hypertension in Mongolian population.
authors.affiliation: Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Gao
authors.forename: Guiyan
authors.initials: G
authors.lastname: Wang
authors.forename: Aili
authors.initials: A
authors.lastname: Wang
authors.forename: Tan
authors.initials: T
authors.lastname: Xu
authors.forename: Weijun
authors.initials: W
authors.lastname: Tong
authors.forename: Yonghong
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000208:ethnology*; D064237:Lipid Accumulation Product / Q000502:physiology*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D014280:Triglycerides