title: Is being an elderly woman a risk factor for worse outcomes after percutaneous coronary intervention? A large cohort study from one center.
abstract: It has remained undefined whether the combination of being elderly (ie, >75 years old) and female is a risk factor for worse outcomes after percutaneous coronary intervention (PCI). A total of 29 211 consecutive patients who underwent PCI were analyzed. Kaplan-Meier estimated 3-year rate of cardiac death was significantly higher in elderly females in comparison with all other groups (P < .05). Using Cox proportional hazard models, being an elderly female was a significant risk factor for cardiac death and cardiac death/MI in comparison with being a young female, OR (95% CI): 2.53 (1.15-5.59), 2.26 (1.27-4.03), or young male, OR (95% CI): 2.22 (1.26-3.91), 2.25 (1.44-3.51); however, it was not a significant risk factor in comparison with being elderly male, OR (95% CI): 1.30 (0.97-1.71), 1.21(0.94-1.55). Elderly females had worse outcomes after PCI therapy than other gender and age groups, but being an elderly female was not an independent risk factor for worse PCI outcomes.
authors.affiliation: State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
authors.forename: Zhan
authors.initials: Z
authors.lastname: Gao
authors.affiliation: State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China jinqing_yuan@hotmail.com.
authors.forename: Jin-Qing
authors.initials: JQ
authors.lastname: Yuan
authors.affiliation: State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
authors.forename: Bo
authors.initials: B
authors.lastname: Xu
authors.affiliation: State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
authors.forename: Yue-Jin
authors.initials: YJ
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
authors.forename: Jue
authors.initials: J
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
authors.forename: Ji-Lin
authors.initials: JL
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
authors.forename: Shu-Bin
authors.initials: SB
authors.lastname: Qiao
authors.affiliation: State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
authors.forename: Yong-Jian
authors.initials: YJ
authors.lastname: Wu
authors.affiliation: State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
authors.forename: Hong-Bin
authors.initials: HB
authors.lastname: Yan
authors.affiliation: State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
authors.forename: Run-Lin
authors.initials: RL
authors.lastname: Gao
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003327:Coronary Disease / Q000175:diagnosis / Q000601:surgery; D054855:Drug-Eluting Stents / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects / Q000379:methods; D012307:Risk Factors; D012727:Sex Characteristics; D016896:Treatment Outcome
keywords: elderly women; outcomes; percutaneous coronary intervention