title: Mass spectrometry analysis of nucleosides and nucleotides.
abstract: Mass spectrometry has been widely utilised in the study of nucleobases, nucleosides and nucleotides as components of nucleic acids and as bioactive metabolites in their own right. In this review, the application of mass spectrometry to such analysis is overviewed in relation to various aspects regarding the analytical mass spectrometric and chromatographic techniques applied and also the various applications of such analysis.
authors.affiliation: Institute of Mass Spectrometry, College of Medicine, Swansea University, Singleton Park, Swansea, SA2 8PP, UK.
authors.forename: Ed
authors.initials: E
authors.lastname: Dudley
authors.forename: Liz
authors.initials: L
authors.lastname: Bond
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002853:Chromatography, Liquid / Q000379:methods; D003199:Computer Systems; D018736:DNA Adducts / Q000032:analysis; D019175:DNA Methylation; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods*; D015394:Molecular Structure; D009705:Nucleosides / Q000032:analysis* / Q000302:isolation & purification / Q000652:urine; D009711:Nucleotides / Q000032:analysis*; D012323:RNA Processing, Post-Transcriptional; D012343:RNA, Transfer / Q000032:analysis
chemical_list: D018736:DNA Adducts; D009705:Nucleosides; D009711:Nucleotides; D012343:RNA, Transfer
keywords: DNA adducts; modified nucleosides; nucleosides; nucleotides