title: Changes in contractile activity of the large intestine in rabbits during the poststress period before and after blockade of muscarinic and nicotinic receptors.
abstract: The rabbits were exposed twice to stress, fixation to a frame in the supine position, for 60 min. Contractile activity of all portions of the large intestine was shown to increase significantly during the poststress period. These changes were not observed under conditions of blockade of muscarinic and nicotinic receptors. This state can be considered as dyskinesia impairing large intestinal transit of chyme.
authors.affiliation: Department for Physiology of Visceral Systems, Research Institute of Experimental Medicine, Northwestern Division of the Russian Academy of Medical Sciences, Saint Petersburg, Russia. vladovs@mail.ru.
authors.forename: T P
authors.initials: TP
authors.lastname: Berezina
authors.forename: V I
authors.initials: VI
authors.lastname: Ovsyannikov
mesh_terms: D000200:Action Potentials; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D006584:Hexamethonium Compounds / Q000494:pharmacology*; D007420:Intestine, Large / Q000187:drug effects / Q000503:physiopathology*; D008297:Male; D018727:Muscarinic Antagonists / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects*; D018733:Nicotinic Antagonists / Q000494:pharmacology*; D010115:Oxyphenonium / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology; D011817:Rabbits; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000503:physiopathology*
chemical_list: D000319:Adrenergic beta-Antagonists; D006584:Hexamethonium Compounds; D018727:Muscarinic Antagonists; D018733:Nicotinic Antagonists; D011433:Propranolol; D010115:Oxyphenonium; C021628:benzohexonium