title: Preparation of monodispersed macroporous core-shell molecularly imprinted particles and their application in the determination of 2,4-dichlorophenoxyacetic acid.
abstract: Porous polymers have aroused extensive attention due to their controllable porous structure in favor of mass transfer and binding capacity. In this work, the novel macroporous core-shell molecularly imprinted polymers (MIP) for selective recognition of 2,4-dichlorophenoxyacetic acid (2,4-D) were prepared by surface initiated atom transfer radical polymerization (si-ATRP). By using one-step swelling and polymerization method, the monodispersed macroporous poly(glycidyl methacrylate) (PGMA) particles were synthesized and used as supporting matrix for preparing surface MIP particles (PGMA@MIP). Thanks to the inner and outer surface-located binding cavities and the macroporous structure, the PGMA@MIPs revealed desirable efficiency for template removal and mass transfer, and thus excellent accessibility and affinity toward template 2,4-D. Moreover, PGMA@MIPs exhibited much higher selectivity toward 2,4-D than PGMA@NIPs. PGMA@MIP particles were directly used to selectively enrich 2,4-D from tap water and the recoveries of 2,4-D were obtained as 90.0-93.4% with relative standard division of 3.1-3.4% (n=3). The macroporous PGMA@MIPs also possessed steady and excellent reusable performance for 2,4-D in four extraction/stripping cycles. This novel macroporous core-shell imprinted material may become a powerful tool for rapid and efficient enrichment and separation of target compounds from the complicated samples.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Lab of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Yongliang
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Lab of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Yonghuan
authors.initials: Y
authors.lastname: He
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Lab of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Yulong
authors.initials: Y
authors.lastname: Jin
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Lab of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Lab of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Guoquan
authors.initials: G
authors.lastname: Liu
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Lab of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. Electronic address: zhaorui@iccas.ac.cn.
authors.forename: Rui
authors.initials: R
authors.lastname: Zhao
mesh_terms: D015084:2,4-Dichlorophenoxyacetic Acid / Q000032:analysis*; D000042:Absorption; D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D007700:Kinetics; D008689:Methacrylates / Q000138:chemical synthesis* / Q000737:chemistry*; D008854:Microscopy, Electron; D054802:Molecular Imprinting; D058105:Polymerization; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D016062:Porosity; D017550:Spectroscopy, Fourier Transform Infrared; D014881:Water Supply
chemical_list: D004852:Epoxy Compounds; D008689:Methacrylates; D011108:Polymers; D015084:2,4-Dichlorophenoxyacetic Acid; C007870:glycidyl methacrylate
keywords: 2,4-Dichlorophenoxyacetic acid; Atom transfer radical polymerization; Core–shell molecularly imprinted polymer; Macroporous structure; Poly(glycidyl methacrylate) particles