title: The use of a magnesium-based bone cement to secure immediate dental implants.
abstract: OBJECTIVE
  The use of a magnesium-based bone cement, OsteoCrete, has shown promise as a means to secure bone and tendon-to-bone connections in orthopedic medicine. The presence of a bone cement to fill the residual socket and stabilize a dental implant during healing could make immediate implant placement in molar sites more predictable. The aim of this study was to determine whether this magnesium-based bone cement can be used predictably for this purpose.
  
  
  METHODS
  The mandibular third premolars and first molars were extracted bilaterally from four mongrel dogs (60 to 80 lb each). Implants were placed in each extraction socket and supported by only 2 to 3 mm of apical furcation bone. OsteoCrete bone cement was placed randomly for implant stabilization in half of the sites. Clinical healing was evaluated until the 4-month time point. All animals were then sacrificed, and mandibular en bloc resection was performed for histologic evaluation of the biologic response and bone-to-implant contact.
  
  
  RESULTS
  Clinically, healing showed a poor response when the test site implant was left exposed in a one-stage manner. No statistically significant difference was noted in bone-to-implant contact (52% in test sites versus 44% in control sites). Histologic specimens showed no adverse biologic response to the material but only minimal replacement at 4 months.
  
  
  CONCLUSIONS
  OsteoCrete bone cement was successful in stabilizing the immediate dental implant in a large extraction socket when placed in a closed environment in the dog model but did not show a benefit as compared to controls. The limited data warrant further studies to determine the further potential of this material.
authors.forename: Brandon M
authors.initials: BM
authors.lastname: Sehlke
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Wilson
authors.forename: Archie A
authors.initials: AA
authors.lastname: Jones
authors.forename: Motofumi
authors.initials: M
authors.lastname: Yamashita
authors.forename: David L
authors.initials: DL
authors.lastname: Cochran
mesh_terms: D000818:Animals; D001641:Bicuspid / Q000601:surgery; D001843:Bone Cements / Q000627:therapeutic use*; D003758:Dental Implantation, Endosseous / Q000379:methods*; D017268:Dental Prosthesis Retention / Q000379:methods*; D004285:Dogs; D017616:Magnesium Compounds / Q000627:therapeutic use*; D008334:Mandible; D008963:Molar / Q000601:surgery; D016348:Osseointegration; D010710:Phosphates / Q000627:therapeutic use*; D014081:Tooth Extraction; D020390:Tooth Socket / Q000601:surgery; D014945:Wound Healing
chemical_list: D001843:Bone Cements; D017616:Magnesium Compounds; C542722:OsteoCrete; D010710:Phosphates