title: McArdle's disease: a clinical review and case report.
abstract: McArdle's Disease is a rare glycogen disease involving deficiency in muscle phosphorylase. This deficiency can lead to rhabdomyolysis and subsequently renal failure. McArdle's Disease has a similar presentation as several other metabolic myopathies with exercise-induced fatigue, myalgias, weakness or unexplained rhabdomyolysis. Suspicion should be raised in the presence of unexplained symptoms, and muscle biopsy can be done to confirm the diagnosis.
authors.affiliation: Chattanooga Emergency Medicine, TN, USA. bradleykeel@gmail.com
authors.forename: Bradley R
authors.initials: BR
authors.lastname: Keel
authors.forename: Michael
authors.initials: M
authors.lastname: Brit
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D024982:Glycogen Phosphorylase, Muscle Form / Q000378:metabolism; D006012:Glycogen Storage Disease Type V / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008297:Male; D017285:Polymyositis / Q000503:physiopathology; D012206:Rhabdomyolysis / Q000503:physiopathology
chemical_list: D024982:Glycogen Phosphorylase, Muscle Form