title: Pulmonary drug toxicity: presentation of a case of recurrent diffuse alveolar damage caused by paroxetine.
abstract: Pulmonary drug toxicity is being diagnosed more often as a cause of acute and chronic lung disease. Numerous agents including cytotoxic and noncytotoxic drugs have the potential to cause pulmonary toxicity. Recurrent diffuse alveolar damage is a rare manifestation of drug toxicity. We described an extremely rare case of recurrent diffuse alveolar damage caused by the antidepressant drug (paroxetine) resolved by a definitive suspension of the drug, after a recurrent respiratory failure because of inadvertently administering the drug.
authors.affiliation: 1Respiratory Diseases Unit, Hospital of Sestri Levante, Sestri Levante, Italy; 2Histopathology Unit, Hospital of Sestri Levante, Sestri Levante, Italy; 3Department of Pathology, Ospedali Civili Brescia, Brescia, Italy; and 4Forensic Medicine ASL4, Chiavari, Italy.
authors.forename: Nicolini
authors.initials: N
authors.lastname: Antonello
authors.forename: Lanata
authors.initials: L
authors.lastname: Sergio
authors.forename: Tironi
authors.initials: T
authors.lastname: Andrea
authors.forename: Barlascini
authors.initials: B
authors.lastname: Cornelius
mesh_terms: D000328:Adult; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects; D005260:Female; D006801:Humans; D017374:Paroxetine / Q000009:adverse effects*; D011650:Pulmonary Alveoli / Q000187:drug effects* / Q000473:pathology; D012008:Recurrence; D012131:Respiratory Insufficiency / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D018687:Antidepressive Agents, Second-Generation; D017374:Paroxetine