title: [Preoperative sonovue contrast color Doppler in patients with cervical cancer. Preliminary report].
abstract: OBJECTIVE
  Angiogenesis has gained much attention in oncology in recent years. The purpose of this pilot study was to describe the preoperative sonographic patterns of SonoVue Contrast-Doppler ultrasound and the standard Color Dopper ultrasound of cervical cancer tumor angiogenesis.
  
  
  METHODS
  This is a prospective observational study. The study included fifteen patients with proven cervical cancer.
  
  
  RESULTS
  Contrast Doppler US after the SonoVue injection gave a good picture of the intense intralesional tumor angiogenesis. Of the 15 patients with FIGO stage lb1 Contrast-sonography showed 12 patients stage Ib1, 1-stage Ib2, 1-stage IIb and 1-stage Iva at final diagnosis.
  
  
  CONCLUSIONS
  SonoVue Contrast Doppler Ultrasound gave a better definition of the margins of the neoplastic lesions in the cervical cancer Because contrast agents increase the sensitivity of detection of parametrial invasion and lymph node metastases, they could pay an important role in the evaluation of uterine cervical cancer
authors.forename: M
authors.initials: M
authors.lastname: Malinova
mesh_terms: D000328:Adult; D002584:Cervix Uteri / Q000098:blood supply* / Q000000981:diagnostic imaging* / Q000473:pathology; D003287:Contrast Media; D005260:Female; D006801:Humans; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging* / Q000473:pathology; D010743:Phospholipids; D010865:Pilot Projects; D011446:Prospective Studies; D013459:Sulfur Hexafluoride; D018615:Ultrasonography, Doppler, Color; D002583:Uterine Cervical Neoplasms / Q000098:blood supply* / Q000000981:diagnostic imaging* / Q000473:pathology
chemical_list: D003287:Contrast Media; D010743:Phospholipids; C420843:contrast agent BR1; D013459:Sulfur Hexafluoride