title: Peripheral nerve repair and reconstruction.
abstract: When possible, direct repair remains the current standard of care for the repair of peripheral nerve lacerations. In large nerve gaps, in which direct repair is not possible, grafting remains the most viable option. Nerve scaffolds include autologous conduits, artificial nonbioabsorbable conduits, and bioabsorbable conduits and are options for repair of digital nerve gaps that are <3 cm in length. Experimental studies suggest that the use of allografts may be an option for repairing larger sensory nerve gaps without associated donor-site morbidity.
authors.affiliation: Department of Orthopaedic Surgery, University of Virginia Health System, 400 Ray C. Hunt Drive, Suite 330, P.O. Box 800159, Charlottesville, VA 22908-0159.
authors.forename: Justin W
authors.initials: JW
authors.lastname: Griffin
authors.forename: MaCalus V
authors.initials: MV
authors.lastname: Hogan
authors.forename: A Bobby
authors.initials: AB
authors.lastname: Chhabra
authors.forename: D Nicole
authors.initials: DN
authors.lastname: Deal
mesh_terms: D064592:Autografts; D003094:Collagen / Q000627:therapeutic use; D003952:Diagnostic Imaging / Q000379:methods; D006801:Humans; D009416:Nerve Regeneration / Q000502:physiology*; D019635:Neurosurgical Procedures / Q000379:methods; D059348:Peripheral Nerve Injuries / Q000175:diagnosis / Q000601:surgery*; D010525:Peripheral Nerves / Q000502:physiology / Q000601:surgery*; D011100:Polyglycolic Acid / Q000627:therapeutic use; D013524:Surgical Flaps; D061665:Time-to-Treatment; D054457:Tissue Scaffolds; D016896:Treatment Outcome
chemical_list: D011100:Polyglycolic Acid; D003094:Collagen