title: Prematurity due to maternal brucella infection and review of the literature.
abstract: Brucellosis is a zoonosis caused by ingestion of unpasteurized milk or other dairy products from infected animals or through close contact with their secretions. Human-to-human transmission, which is rare, has been reported in association with blood transfusion, bone marrow transplantation, transplacental or perinatal exposure, and breastfeeding. In the neonatal period, congenital brucellosis, which is an extremely rare condition, can lead to serious clinical consequences with a high morbidity and mortality rate. The case presented here is a premature baby born at 25 weeks' gestation to a mother suffering from severe oligohydramnios, premature rupture of membranes and untreated acute brucellosis. The baby had severe respiratory distress and radiological findings compatible with pulmonary infection. The blood cultures of the baby and the mother were positive for Brucella melitensis, supporting the diagnosis of brucellosis with presumed transplacental transmission.
authors.affiliation: Division of Neonatology Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital, Ankara, Turkey. serbeken@gmail.com.
authors.forename: Banu
authors.initials: B
authors.lastname: Aydın
authors.forename: Serdar
authors.initials: S
authors.lastname: Beken
authors.forename: Ragıp
authors.initials: R
authors.lastname: Akansel
authors.forename: Dilek
authors.initials: D
authors.lastname: Dilli
authors.forename: Nurullah
authors.initials: N
authors.lastname: Okumuş
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Zenciroğlu
authors.forename: Gönül
authors.initials: G
authors.lastname: Tanır
mesh_terms: D000328:Adult; D001803:Blood Transfusion; D001942:Breast Feeding; D017347:Brucella melitensis / Q000302:isolation & purification*; D002006:Brucellosis / Q000175:diagnosis* / Q000382:microbiology / Q000635:transmission; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000382:microbiology*; D008171:Lung Diseases / Q000175:diagnosis* / Q000382:microbiology; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious