title: Documentation of atrial fibrillation prior to first-ever ischemic stroke.
abstract: OBJECTIVE
  We assessed the prevalence of atrial fibrillation (AF) prior to first-ever ischemic stroke by examining a comprehensive electronic ECG archive.
  
  
  METHODS
  The study sample comprised 336 consecutive stroke patients (median age 76 (IQ16) y, 200 men) enrolled in Lund Stroke Register from March 2001 to February 2002 and 336 age- and gender-matched controls without stroke history. AF prior to admission was studied using the regional electronic ECG database and record linkage with the National Swedish Hospital Discharge Register (SHDR). Medical records were reviewed for AF documentation and CHA2 DS2-VASc risk score.
  
  
  RESULTS
  Atrial fibrillation before or at stroke onset was detected in 109 (32.4%) stroke patients and 44 (13.1%) controls, P<0.001. Twenty-five of 109 stroke patients had AF detected only on previous ECG (n=14) or through the SHDR (n=11). The most prevalent type of AF in stroke group was non-permanent AF (59.6%). AF prevalence among patients admitted with sinus rhythm at hospital admission (n=266) was higher in those with CHA2 DS2 -VASc score≥6 (28.6%) than with CHA2 DS2-VASc score<6 (13.0%), P=0.043.
  
  
  CONCLUSIONS
  Comprehensive approach for AF screening allows detecting AF in one-third of patients admitted with first-ever ischemic stroke. Patients with high cardiovascular risk are more likely to have non-permanent AF.
authors.affiliation: Department of Cardiology, Lund University, Lund, Sweden; North-West Center for Diagnostics and Treatment of Arrythmias, St.Petersburg State University, St. Petersburg, Russia.
authors.forename: M A
authors.initials: MA
authors.lastname: Baturova
authors.forename: A
authors.initials: A
authors.lastname: Lindgren
authors.forename: Y V
authors.initials: YV
authors.lastname: Shubik
authors.forename: S B
authors.initials: SB
authors.lastname: Olsson
authors.forename: P G
authors.initials: PG
authors.lastname: Platonov
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000453:epidemiology*; D002545:Brain Ischemia / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D016208:Databases, Factual; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D010343:Patient Admission; D015995:Prevalence; D011446:Prospective Studies; D012042:Registries; D012189:Retrospective Studies; D012720:Severity of Illness Index; D020521:Stroke / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D013548:Sweden / Q000453:epidemiology; D013997:Time Factors
chemical_list: D000925:Anticoagulants
keywords: ECG; atrial fibrillation; first-ever ischemic stroke; stroke register