title: Experience with bone morphogenetic protein-2 and interpositional grafting of edentulous maxillae: a comparison of Le Fort I downfracture to full-arch (horseshoe) segmental osteotomy done in conjunction with sinus floor grafting.
abstract: This paper is a retrospective report of the treatment of six patients with severely resorbed maxillae. Patients were treated, based on the amount of maxillary retrognathia, with either a Le Fort I downfracture or a "horseshoe" interpositional sandwich osteotomy, along with sinus elevation. Recombinant human bone morphogenetic protein-2 in an absorbable collagen sponge carrier was used for grafting in all patients, either alone or in combination with other grafting materials. Implants were placed and the patients were restored with fixed prostheses. Both grafting techniques are described, and the treated patients are presented.
authors.forename: Ole T
authors.initials: OT
authors.lastname: Jensen
authors.forename: Jared R
authors.initials: JR
authors.lastname: Cottam
authors.forename: Jason L
authors.initials: JL
authors.lastname: Ringeman
authors.forename: Aldo
authors.initials: A
authors.lastname: Leopardi
authors.forename: Brian
authors.initials: B
authors.lastname: Butler
authors.forename: Amir
authors.initials: A
authors.lastname: Laviv
authors.forename: Yoram
authors.initials: Y
authors.lastname: Fleissig
authors.forename: Nardy
authors.initials: N
authors.lastname: Casap
mesh_terms: D000368:Aged; D055396:Bone Morphogenetic Protein 2 / Q000008:administration & dosage*; D003758:Dental Implantation, Endosseous / Q000379:methods; D005260:Female; D005781:Gelatin Sponge, Absorbable; D006801:Humans; D007575:Jaw, Edentulous / Q000601:surgery; D008297:Male; D008437:Maxilla; D008439:Maxillary Diseases / Q000601:surgery*; D008488:Medical Illustration; D008875:Middle Aged; D019340:Osteotomy, Le Fort / Q000295:instrumentation / Q000379:methods*; D011994:Recombinant Proteins / Q000008:administration & dosage; D063173:Retrognathia / Q000601:surgery*; D012189:Retrospective Studies; D059546:Sinus Floor Augmentation / Q000379:methods*; D016212:Transforming Growth Factor beta / Q000008:administration & dosage*
chemical_list: D055396:Bone Morphogenetic Protein 2; D011994:Recombinant Proteins; D016212:Transforming Growth Factor beta; C499469:recombinant human bone morphogenetic protein-2