title: Stroke after burn: population data analysis.
abstract: OBJECTIVE
  We aimed to describe a population cohort study of burns with the prevalence of stroke, and discuss possible etiologies.
  
  
  METHODS
  This study uses data obtained from the Longitudinal Health Insurance Database 2005 (LHID2005). The study cohort consisted of all patients who had diagnoses of burn recorded in the database (ICD-9-CM codes 948) between January 1 2004 and December 31 2008 (N=1549).
  
  
  RESULTS
  The patients with burn and the comparison cohort are 7410 patients, 146 experienced stroke during the follow-up period of up to 5 years. In average, the burn patients suffered from stroke by 1.48 years after burn. The hazard ratio of stroke was 1.74 (95% CI, 1.15-2.63) for patients with TBSA burn <20%, 3.78 (95% CI, 1.39-10.26) for patients with TBSA burn ≥20%. The adjusted hazard ratio of ischemic stroke was 1.63 for patients with TBSA burn <20%, 2.96 for patients with TBSA burn ≥20%, whereas the hazard ratio of hemorrhagic stroke were not significant (p=0.231).
  
  
  CONCLUSIONS
  In our study, severe burned patients, more than 60 years of age, had higher risk of stroke in their recovery life. We suggest close follow up for the burn patients in high risk of stroke.
authors.affiliation: Division of Plastic Surgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taiwan; Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taiwan; Evidence-Based Medicine Center, Wan Fang Hospital, Taipei Medical University, Taiwan; Center for Evidence-Based Medicine, Taipei Medical University, Taiwan.
authors.forename: Chiehfeng
authors.initials: C
authors.lastname: Chen
authors.affiliation: Division of Plastic Surgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taiwan; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taiwan.
authors.forename: Chun-Yuan
authors.initials: CY
authors.lastname: Huang
authors.affiliation: Division of Plastic Surgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taiwan; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taiwan.
authors.forename: Hsian-Jenn
authors.initials: HJ
authors.lastname: Wang
authors.affiliation: Department of Neurology, Wan Fang Hospital, Taipei Medical University, Taiwan.
authors.forename: Chin-I
authors.initials: CI
authors.lastname: Chen
authors.affiliation: Evidence-Based Medicine Center, Wan Fang Hospital, Taipei Medical University, Taiwan; Department of Mathematics, Soochow University, Taipei, Taiwan. Electronic address: hwlin@scu.edu.tw.
authors.forename: Hui-Wen
authors.initials: HW
authors.lastname: Lin
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001830:Body Surface Area; D002545:Brain Ischemia / Q000150:complications / Q000453:epidemiology*; D002056:Burns / Q000453:epidemiology* / Q000473:pathology; D016022:Case-Control Studies; D002543:Cerebral Hemorrhage / Q000150:complications / Q000453:epidemiology*; D015331:Cohort Studies; D016208:Databases, Factual; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D020521:Stroke / Q000453:epidemiology* / Q000209:etiology; D013624:Taiwan / Q000453:epidemiology
keywords: Burn; Health Insurance Database; Stroke