title: Evaluation of health-related physical fitness parameters and association analysis with depression, anxiety, and quality of life in patients with fibromyalgia.
abstract: OBJECTIVE
  The purpose of this study was to investigate the physical fitness parameters (maximal aerobic capacity, muscle strength and flexibility), daily physical activity, resting metabolic rate (RMR), pulmonary function tests (PFTs), body composition, depression, anxiety and health-related quality of life (HRQoL) changes as well as the associations among these parameters in patients with fibromyalgia and to compare them with healthy controls.
  
  
  METHODS
  Thirty-nine women with fibromyalgia and 40 controls were included in this study. Physical measurements, HRQoL questionnaire, Beck Depression Inventory (BDI) score and Beck Anxiety Inventory (BAI) score were applied to all participants.
  
  
  RESULTS
  Maximal aerobic capacity, trunk flexibility, daily step numbers, total energy expenditure, RMR and PFT values were not significantly different between the patients and the controls. Fibromyalgia patients had higher daily moderate activity times, active energy expenditure values, and BDI and BAI scores, while their lower handgrip strength and back-leg strength values and Short-form health survey (SF)-36 scores were comparable to controls. Handgrip strength and back-leg strength values showed moderately positive correlations with SF-36 scores (total, physical health, mental health) and moderately negative correlations with BDI and BAI scores in patients with fibromyalgia.
  
  
  CONCLUSIONS
  Our results suggested that muscle strength, HRQoL, depression and anxiety symptomatology were impaired in fibromyalgia patients compared to healthy controls. Low muscle strength is related to reduced HRQoL and increased depression and anxiety symptomatology in patients with fibromyalgia. Also we suggest that performing daily exercises, including aerobic and strength training, as part of one's lifestyle may have beneficial effects in fibromyalgia patients.
authors.affiliation: Department of Physiology, Faculty of Medicine, Namik Kemal University, Tekirdag, Turkey.
authors.forename: Umit
authors.initials: U
authors.lastname: Sener
authors.affiliation: Department of Physiology, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Kagan
authors.initials: K
authors.lastname: Ucok
authors.affiliation: Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Alper M
authors.initials: AM
authors.lastname: Ulasli
authors.affiliation: Department of Physiology, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Genc
authors.affiliation: Department of Physiology, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Hatice
authors.initials: H
authors.lastname: Karabacak
authors.affiliation: Department of Physiology, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Necip F
authors.initials: NF
authors.lastname: Coban
authors.affiliation: Department of Physiology, Faculty of Medicine, Dumlupinar University, Kutahya, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Simsek
authors.affiliation: Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Halime
authors.initials: H
authors.lastname: Cevik
mesh_terms: D000328:Adult; D001007:Anxiety / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000523:psychology; D016022:Case-Control Studies; D003863:Depression / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000523:psychology; D004734:Energy Metabolism; D017079:Exercise Tolerance; D005260:Female; D005356:Fibromyalgia / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D006304:Health Status; D006801:Humans; D008168:Lung / Q000503:physiopathology; D008603:Mental Health; D008875:Middle Aged; D053580:Muscle Strength; D010809:Physical Fitness; D011379:Prognosis; D011788:Quality of Life; D016059:Range of Motion, Articular; D012129:Respiratory Function Tests; D011795:Surveys and Questionnaires
keywords: anxiety; daily physical activity; depression; fibromyalgia; quality of life; strength