title: Pacemaker-related infection detected by (18)F-fluorodeoxyglucose positron emission tomography-computed tomography.
abstract: Lead endocarditis (LE) is one of the most feared complications and remains a challenging diagnosis in cardiology due to the possibility of an obscure clinical course and symptoms, leading to a delayed diagnosis, or even no diagnosis. (18)F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) appears to be a valuable imaging technique and has been shown to have advantages in the diagnosis of patients with fever of unknown origin. We present the case of a 52-year-old man with a 3-year history of intermittent fever, chills, anemia, and weight loss (13kg). He was submitted to an extensive investigation to clarify his symptoms and all results were negative. LE was finally diagnosed by FDG PET/CT. This examination could become a useful noninvasive method for the detection of LE at an earlier stage, thus avoiding repeated tests and reducing the length of hospital stay.
authors.affiliation: Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Enéas de Caravalho Aguiar, 44, CEP 05403-000, São Paulo, SP, Brazil. Electronic address: giselle.peixoto@incor.usp.br.
authors.forename: Giselle
authors.initials: G
authors.lastname: de Lima Peixoto
authors.affiliation: Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Enéas de Caravalho Aguiar, 44, CEP 05403-000, São Paulo, SP, Brazil.
authors.forename: Rinaldo Focaccia
authors.initials: RF
authors.lastname: Siciliano
authors.affiliation: Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Enéas de Caravalho Aguiar, 44, CEP 05403-000, São Paulo, SP, Brazil.
authors.forename: Raphael Abegão
authors.initials: RA
authors.lastname: Camargo
authors.affiliation: Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Enéas de Caravalho Aguiar, 44, CEP 05403-000, São Paulo, SP, Brazil.
authors.forename: Fabiana Lucas
authors.initials: FL
authors.lastname: Bueno
authors.affiliation: Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Enéas de Caravalho Aguiar, 44, CEP 05403-000, São Paulo, SP, Brazil.
authors.forename: José Soares
authors.initials: JS
authors.lastname: Júnior
authors.affiliation: Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Enéas de Caravalho Aguiar, 44, CEP 05403-000, São Paulo, SP, Brazil.
authors.forename: Roberto
authors.initials: R
authors.lastname: Costa
authors.affiliation: Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Enéas de Caravalho Aguiar, 44, CEP 05403-000, São Paulo, SP, Brazil.
authors.forename: Tânia Mara Varejão
authors.initials: TM
authors.lastname: Strabelli
authors.affiliation: Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Enéas de Caravalho Aguiar, 44, CEP 05403-000, São Paulo, SP, Brazil.
authors.forename: Martino Martinelli
authors.initials: MM
authors.lastname: Filho
mesh_terms: D000740:Anemia; D003937:Diagnosis, Differential; D059905:Endocarditis, Non-Infective / Q000000981:diagnostic imaging / Q000209:etiology*; D005335:Fever of Unknown Origin / Q000000981:diagnostic imaging / Q000209:etiology*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial / Q000009:adverse effects*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D012086:Reoperation; D012680:Sensitivity and Specificity; D015431:Weight Loss
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Endocarditis; FDG-PET; Infection; Pacemaker