title: Checklist for standardized reporting of drug-drug interaction management guidelines.
abstract: OBJECTIVE
  Inconsistencies and omissions in drug-drug interaction (DDI) management guidelines may lead to harm and suboptimal therapy. The purpose of this study was to define a checklist for DDI management guidelines to help developers produce high-quality guidelines that will support healthcare providers in clinical practice.
  
  
  METHODS
  We carried out a two-round Delphi process with an international panel of healthcare providers, most of whom are pharmacists involved in providing DDI information, in order to select those items that should be addressed in DDI management guidelines (including grading systems that could be used).
  
  
  RESULTS
  Twenty-three panellists reached consensus on 19 items in two main domains. These were consolidated into a checklist of 15 elements for standardized reporting in management guidelines. For each element a description is provided to specify what information should be documented in that specific element.
  
  
  CONCLUSIONS
  It was possible to reach a broad consensus on which relevant items should be included in a checklist for the development of DDI management guidelines.
authors.affiliation: SIR Institute for Pharmacy Practice and Policy, Theda Mansholtstraat 5B, 2331 JE, Leiden, The Netherlands, a.floor@stevenshof.nl.
authors.forename: Annemieke
authors.initials: A
authors.lastname: Floor-Schreudering
authors.forename: Arjen F J
authors.initials: AF
authors.lastname: Geerts
authors.forename: Jeffrey K
authors.initials: JK
authors.lastname: Aronson
authors.forename: Marcel L
authors.initials: ML
authors.lastname: Bouvy
authors.forename: Robin E
authors.initials: RE
authors.lastname: Ferner
authors.forename: Peter A G M
authors.initials: PA
authors.lastname: De Smet
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems / Q000592:standards*; D057189:Checklist; D032921:Consensus; D003697:Delphi Technique; D004347:Drug Interactions; D006801:Humans; D010595:Pharmacists / Q000592:standards; D017410:Practice Guidelines as Topic / Q000592:standards*