title: The relationship between high-sensitive troponin T, neutrophil lymphocyte ratio and SYNTAX Score.
abstract: OBJECTIVE
  Cardiac troponins are the most preferred biomarkers in the evaluation of acute coronary syndromes (ACS). The aim of our study was to examine the association between high sensitive troponin T (hs-TnT), and neutrophil to lymphocyte ratio (NLR) and the complexity of ACS assessed by SYNTAX Score.
  
  
  RESULTS
  287 patients who underwent coronary angiography were studied (215 male, mean age 62.0 ± 12.7 years). 133 patients were ST elevation myocardial infarction (STEMI), 154 patients were non-ST elevation (NSTE) ACS . The patients are divided to tertiles according to SYNTAX Score; SYNTAX Score ≤ 22 (n = 122) 22 < SYNTAX Score ≤ 32 (n = 120), and SYNTAX Score > 32 (n = 45). NLR was significantly correlated with SYNTAX Score in both STEMI and NSTE-ACS groups (r = 0.254, p = 0.003, r = 0.419 p < 0.001). Multiple linear regression analysis showed NLR predicted the angiographic severity of ACS assessed by SYNTAX Score in two groups (β = 0.231, p = 0.004; β = 0.232, p = 0.003). Hs-TnT was significantly correlated with SYNTAX Score in two groups (r = 0.327, p < 0.001; r = 0.430, p < 0.001). Multiple linear regression analysis showed hs-TnT was independent predictor of SYNTAX Score in STEMI and NSTE-ACS patients (β = 0.292, p < 0.001; β = 0.317, p < 0.001).
  
  
  CONCLUSIONS
  Hs-TnT and NLR were significantly correlated with angiographic severity of ACS assessed by SYNTAX Score.
authors.affiliation: Department of Cardiology.
authors.forename: Burak
authors.initials: B
authors.lastname: Altun
authors.forename: Hakan
authors.initials: H
authors.lastname: Turkon
authors.forename: Hakan
authors.initials: H
authors.lastname: Tasolar
authors.forename: Halıl
authors.initials: H
authors.lastname: Beggı
authors.forename: Mehzat
authors.initials: M
authors.lastname: Altun
authors.forename: Ahmet
authors.initials: A
authors.lastname: Temız
authors.forename: Emıne
authors.initials: E
authors.lastname: Gazı
authors.forename: Ahmet
authors.initials: A
authors.lastname: Barutcu
authors.forename: Adem
authors.initials: A
authors.lastname: Bekler
authors.forename: Yucel
authors.initials: Y
authors.lastname: Colkesen
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D000368:Aged; D015415:Biomarkers / Q000097:blood; D017023:Coronary Angiography; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D009504:Neutrophils / Q000473:pathology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D020107:Troponin T / Q000097:blood
chemical_list: D015415:Biomarkers; D020107:Troponin T