title: Toxicity assessment of SiC nanofibers and nanorods against bacteria.
abstract: In the present study, evidence of the antibacterial effects of silicon carbide (SiC) nanofibers (NFSiC) and nanorods (NRSiC) obtained by combustion synthesis has been presented. It has been shown that the examined bacteria, Pseudomonas putida, could bind to the surface of the investigated SiC nanostructures. The results of respiration measurements, dehydrogenase activity measurements, and evaluation of viable bacteria after incubation with NFSiC and NRSiC demonstrated that the nanostructures of SiC affect the growth and activity of the bacteria examined. The direct count of bacteria stained with propidium iodide after incubation with SiC nanostructures revealed that the loss of cell membrane integrity could be one of the main effects leading to the death of the bacteria.
authors.affiliation: Faculty of Advanced Technologies and Chemistry, Military University of Technology, Kaliskiego 2, 00-908 Warsaw, Poland. Electronic address: mszala@wat.edu.pl.
authors.forename: Mateusz
authors.initials: M
authors.lastname: Szala
authors.affiliation: Faculty of Geology, University of Warsaw, Żwirki i Wigury 93, 02-089 Warsaw, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Borkowski
mesh_terms: D017554:Carbon Compounds, Inorganic / Q000633:toxicity*; D002462:Cell Membrane / Q000187:drug effects; D004789:Enzyme Activation / Q000187:drug effects; D050296:Microbial Viability / Q000187:drug effects; D057139:Nanofibers / Q000633:toxicity*; D043942:Nanotubes / Q000633:toxicity*; D016958:Pseudomonas putida / Q000187:drug effects* / Q000201:enzymology; D017655:Silicon Compounds / Q000633:toxicity*
chemical_list: D017554:Carbon Compounds, Inorganic; D017655:Silicon Compounds; C022088:silicon carbide
keywords: Bacteria; Nanofibers; Nanorods; Silicon carbide; Toxicity