title: Corneal impairment in a patient with type 2 distal arthrogryposis.
abstract: OBJECTIVE
  Case report of a 7-year-old male patient, diagnosed with idiopathic progressive corneal alteration developed within a period of 6 months.
  
  
  METHODS
  Description of type 2 distal arthrogryposis affecting hands and feet, a bilateral, congenital hearing loss, alterations such as keloid-like scarring, congenital heart disease, and cryptorchidism with no relevant family history.
  
  
  RESULTS
  Corrected visual acuity in the right eye (RE) was 0.5 and in the left eye was 1 and, in addition to that, a bilateral corneal subepithelial fibrosis that was denser in the RE without neovessels and no signs of inflammatory activity.
  
  
  CONCLUSIONS
  This is the first publication relating arthrogryposis with corneal affectation, probably because of a collagen anomaly characteristic in these patients.
authors.affiliation: Cornea and Refractive Surgery Unit (J.L.G., P.V., D.E., O.G., F.M.), Instituto de Microcirugia Ocular, Barcelona, Spain; and Department of Ophthalmology (J.L.G., P.V., D.E., O.G., F.M.), Universitat Autònoma de Barcelona, Barcelona, Spain.
authors.forename: Jose L
authors.initials: JL
authors.lastname: Güell
authors.forename: Paula
authors.initials: P
authors.lastname: Verdaguer
authors.forename: Daniel
authors.initials: D
authors.lastname: Elies
authors.forename: Oscar
authors.initials: O
authors.lastname: Gris
authors.forename: Felicidad
authors.initials: F
authors.lastname: Manero
mesh_terms: D001176:Arthrogryposis / Q000150:complications*; D002648:Child; D003316:Corneal Diseases / Q000209:etiology*; D006801:Humans; D008297:Male