title: Antibacterial Screening of Secreted Compounds Produced by the Phase I Variant of Photorhabdus luminescens.
abstract: In this study, antibacterial activity of metabolites secreted by the phase I variant of Photorhabdus luminescens was investigated. Bioactivity of these metabolites was screened against 28 different bacterial species and strains. Bacterial sensitivity was determined by a modified-version of the Kirby-Bauer disk diffusion susceptibility method, whereas the phase I variant's culture permeate was utilized as the "antibacterial" agent. This investigation demonstrates that 11 of the 28 bacterial species tested were sensitive to at least one of the secreted compounds or a combination thereof.
authors.affiliation: Sartorius-Stedim Biotechnology Laboratory, Biotechnology Research and Training Center, University of North Carolina at Pembroke, 115 Livermore Drive, Pembroke, NC 28372 USA.
authors.forename: Floyd L
authors.initials: FL
authors.lastname: Inman Iii
authors.forename: Leonard
authors.initials: L
authors.lastname: Holmes
keywords: Antimicrobials; Heterorhabditis bacteriophora; Phase variation; Photorhabdus luminescens