title: Glycosyl Thioimidates as Versatile Building Blocks for Organic Synthesis.
abstract: This review discusses the synthesis and application of glycosyl thioimidates in chemical glycosylation and oligosaccharide assembly. Although glycosyl thioimidates include a broad range of compounds, the discussion herein centers onS-benzothiazolyl (SBaz),S-benzoxazolyl (SBox),S-thiazolinyl (STaz), andS-benzimidazolyl (SBiz) glycosides. These heterocyclic moieties have recently emerged as excellent anomeric leaving groups that express unique characteristics for highly diastereoselective glycosylation and help to provide the streamlined access to oligosaccharides.
authors.affiliation: University of Missouri - St. Louis, One University Boulevard, St. Louis, Missouri 63121, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: Hasty
authors.forename: A V
authors.initials: AV
authors.lastname: Demchenko
keywords: carbohydrates; glycoconjugates; glycosylation; leaving group; oligosaccharides; thioimidates