title: CD34 expression of chorionic villous in pre-eclamptic placenta: an immunohistochemical and ultrastructural study.
abstract: In this study, pre-eclampsia, proteinuria, and edema associated with hypertension in pregnancy were assessed at the Dicle University School of Medicine Department of Obstetrics and Gynecology Clinic. One group included 20 pre-eclamptic pregnant women with gestational age 20-35 weeks of pregnancy and the same in the control group that included; however, 20 normotensive pregnant women. Histochemistry, immunohistochemistry, and electron microscopy techniques were used. Histopathological examination of syncytial nodes and stromal cells were observed in the increase in hyperplasia and hyalinization. The evaluation immunohistochemical of chorionic villi, placenta, and hematopoietic stem cell markers showed a positive reaction with CD34. Ultrastructural examination showed endoplasmic reticulum dilatation, degeneration of mitochondria in endothelial cells, and capillary vessel edema.
authors.affiliation: Department of Immunology, Dicle University School of Medicine, Diyarbakir, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Kalkanli
authors.forename: E
authors.initials: E
authors.lastname: Deveci
authors.forename: M E
authors.initials: ME
authors.lastname: Sak
authors.forename: M S
authors.initials: MS
authors.lastname: Evsen
authors.forename: O
authors.initials: O
authors.lastname: Baran
authors.forename: S
authors.initials: S
authors.lastname: Ozekinci
authors.forename: D
authors.initials: D
authors.lastname: Yavuz
mesh_terms: D000328:Adult; D018952:Antigens, CD34 / Q000378:metabolism*; D002824:Chorionic Villi / Q000378:metabolism* / Q000648:ultrastructure; D004108:Dilatation, Pathologic; D004721:Endoplasmic Reticulum / Q000473:pathology / Q000648:ultrastructure; D004730:Endothelium, Vascular / Q000473:pathology; D005260:Female; D006412:Hematopoietic Stem Cells / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D008928:Mitochondria / Q000473:pathology; D010920:Placenta / Q000378:metabolism*; D011225:Pre-Eclampsia / Q000378:metabolism* / Q000473:pathology; D011247:Pregnancy
chemical_list: D018952:Antigens, CD34