title: An unusual triphenylphosphine oxide catalyzed stereoselective 1,3-dichlorination of unsaturated ketoesters.
abstract: An unusual Ph3PO-catalyzed stereoselective 1,3-dicholorination of an unsaturated ketoester has been developed. The novel activation mode involved in this cascade reaction can promote consecutively elusive transformations. The products were obtained with good yields and excellent stereoselectivities. This reaction makes important complementation to the limitations associated with the field of dichlorination.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000 (P.R. China), Fax: (+86) 931-8915557.
authors.forename: Tian-Yang
authors.initials: TY
authors.lastname: Yu
authors.forename: Yao
authors.initials: Y
authors.lastname: Wang
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Xu
mesh_terms: D002384:Catalysis; D002713:Chlorine / Q000737:chemistry; D018360:Crystallography, X-Ray; D004952:Esters; D054879:Halogenation; D007659:Ketones / Q000737:chemistry; D008968:Molecular Conformation; D009943:Organophosphorus Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004952:Esters; D007659:Ketones; D009943:Organophosphorus Compounds; D002713:Chlorine; C063888:triphenylphosphine oxide
keywords: 1,3-dichlorination; catalysis; stereoselective; triphenylphosphine oxide; unsaturated ketoesters