title: In vivo performance of the VistaProof fluorescence-based camera for detection of occlusal lesions.
abstract: OBJECTIVE
  The aim of this study was to evaluate the in-vivo performance of the VistaProof fluorescence-based camera (VP) on occlusal surfaces.
  
  
  METHODS
  The study was approved by the ethics committee and informed consent was given by the participants. The study included 306 unrestored permanent teeth of 26 patients. The occlusal surfaces of the teeth were examined visually using International Caries Detection and Assessment System (ICDAS) criteria. Then, digital images of the surfaces were made using the VP. The actual depth of the lesions was assessed using radiographs and/or clinically by opening the lesion when appropriate. Correlation between all methods was assessed using Spearman's rank correlation coefficient (r s ). Sensitivity (SE) and specificity (SP) were calculated at D1-(enamel lesions) and D3-(dentine caries) diagnostic threshold and area under the ROC curve (AUC) were assessed.
  
  
  RESULTS
  Significant positive correlation was found between ICDAS, VP measurements and the reference standard (r s 0.46-0.71, p < 0.01). SE and SP were at D1-diagnostic threshold level 92.3 and 41.1 %, respectively. At D3-diagnostic threshold, SE was 25.9 % and SP 97.9 %. The diagnostic performance (AUC) was 0.82 (D1) and 0.85 (D3). Combination of VP measurements with ICDAS showed the SE value of 74.1 % at D3-diagnostic threshold.
  
  
  CONCLUSIONS
  The VP showed good diagnostic performance. The combination of VP measurements with ICDAS improved the SE in detecting dentine lesions.
authors.affiliation: Department of Paediatric and Community Dentistry, Dental School, Philipps University of Marburg, Georg-Voigt-Str. 3, 35033, Marburg, Germany, momeni@staff.uni-marburg.de.
authors.forename: Anahita
authors.initials: A
authors.lastname: Jablonski-Momeni
authors.forename: Monika
authors.initials: M
authors.lastname: Heinzel-Gutenbrunner
authors.forename: Sarah Marie Christine
authors.initials: SM
authors.lastname: Klein
mesh_terms: D000328:Adult; D003731:Dental Caries / Q000175:diagnosis*; D019229:Dentition, Permanent; D005260:Female; D005453:Fluorescence; D006801:Humans; D008297:Male; D010781:Photography / Q000295:instrumentation*; D019252:Radiography, Dental, Digital