title: Pyridine derivatives, especially 2,6-di-tert-butylpyridine, labeled with nitrogen-15.
abstract: Pyridine derivatives labeled with (15) N can be prepared by the reaction of the corresponding pyrylium salts with (15) NH4 Cl in close to a stoichiometric ratio, in a sodium acetate-acetic acid buffer. In particular, the reaction of 2,6-di-tert-butylpyrylium perchlorate gave 2,6-di-tert-butylpyridine with a conversion of 95%. The compound is valuable for studies of acid-base interactions on solid acid catalysts by (15) N nuclear magnetic resonance.
authors.affiliation: Department of Chemical and Petroleum Engineering, University of Pittsburgh, 1249 Benedum Hall, Pittsburgh, PA, 15261, USA.
authors.forename: Dan
authors.initials: D
authors.lastname: Fărcaşiu
authors.forename: Marta
authors.initials: M
authors.lastname: Lezcano
mesh_terms: D007553:Isotope Labeling / Q000379:methods*; D009587:Nitrogen Isotopes / Q000138:chemical synthesis; D011725:Pyridines / Q000138:chemical synthesis*
chemical_list: D009587:Nitrogen Isotopes; D011725:Pyridines
keywords: 2,6-di-tert-butylpyridine-15N; 2,6-di-tert-butylpyrylium perchlorate; ammonium-15N chloride; pyrylium salts, conversion to pyridines