title: The additional value of blood cultures in patients with complicated urinary tract infections.
abstract: We evaluated 800 hospitalized patients with a complicated urinary tract infection, from whom both a blood and a urine culture were obtained on the first day of antibiotic treatment. Urine cultures were positive in 70% of patients, and blood cultures were positive in 29%. In 7% of patients, uropathogens caused bacteraemia with a pathogen that was not isolated from urine. Receiving antibiotic therapy at the moment of hospitalization was the only factor independently associated with discordant culture results (OR, 2.06; 95% CI, 1.18-3.61). For those receiving antibiotics at the moment of hospitalization, blood cultures have additional diagnostic value over urine cultures.
authors.affiliation: Department of Internal Medicine, Division of Infectious Diseases, Centre for Infection and Immunity Amsterdam, Academic Medical Centre, Nijmegen, the Netherlands.
authors.forename: V
authors.initials: V
authors.lastname: Spoorenberg
authors.forename: J M
authors.initials: JM
authors.lastname: Prins
authors.forename: B C
authors.initials: BC
authors.lastname: Opmeer
authors.forename: T M
authors.initials: TM
authors.lastname: de Reijke
authors.forename: M E J L
authors.initials: ME
authors.lastname: Hulscher
authors.forename: S E
authors.initials: SE
authors.lastname: Geerlings
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology*; D001769:Blood / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D014552:Urinary Tract Infections / Q000150:complications* / Q000382:microbiology*; D014556:Urine / Q000382:microbiology*
keywords: Bacteraemia; culture (blood/urine); diagnostics; risk factors; urinary tract infection