title: A review of trimethylaminuria: (fish odor syndrome).
abstract: Trimethylaminuria, better known as fish odor syndrome, is a psychologically disabling condition in which a patient emits a foul odor, which resembles that of rotting fish. The disorder is most commonly caused by an inherited deficiency in flavin monooxygenase 3, the vital enzyme for the metabolism of trimethylamine, which is the compound responsible for the unpleasant odor. The condition is uncommon, but there has been recent research to suggest that the diagnosis may often be overlooked. Moreover, it is important to be cognizant of this condition because there are reliable diagnostic tests and the disorder can be devastating from a psychosocial perspective. While there is no cure, many simple treatment options exist that may drastically improve the quality of life of these patients. This article will review the literature with an emphasis on the psychosocial impact and treatment options.
authors.affiliation: College of Medicine, The Ohio State University, Columbus, Ohio.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Messenger
authors.forename: Shane
authors.initials: S
authors.lastname: Clark
authors.forename: Susan
authors.initials: S
authors.lastname: Massick
authors.forename: Mark
authors.initials: M
authors.lastname: Bechtel