title: Unique risks for mortality in patients with end-stage renal disease undergoing nonemergent colorectal surgery.
abstract: BACKGROUND
  The aim of this study was to identify unique risk factors for mortality in patients with end-stage renal disease undergoing nonemergent colorectal surgery.
  
  
  METHODS
  A multivariate logistic regression model predicting 30-day mortality was constructed for patients with end-stage renal disease undergoing nonemergent colorectal procedures. Data were obtained from the National Surgical Quality Improvement Program (2005-2010).
  
  
  RESULTS
  Among the 394 patients analyzed, those with serum creatinine levels >7.5 mg/dL had .07 times the adjusted mortality risk of those with levels <3.5 mg/dL. For colorectal surgery patients, the average serum creatinine level was 5.52 ± 2.6 mg/dL, and mortality was 13% (n = 50).
  
  
  CONCLUSIONS
  High serum creatinine was associated with a lower risk for mortality in patients with end-stage renal disease, even though creatinine is often considered a risk factor for surgery. These results show how variables from a patient-centered subpopulation can differ in meaning from the general population.
authors.affiliation: Department of Surgery, Division of Colorectal Surgery, Drexel University College of Medicine, 245 North 15th Street, Suite 7150 NCB, Philadelphia, PA 19102, USA.
authors.forename: James J
authors.initials: JJ
authors.lastname: Liu
authors.affiliation: Department of Surgery, Division of Colorectal Surgery, Drexel University College of Medicine, 245 North 15th Street, Suite 7150 NCB, Philadelphia, PA 19102, USA.
authors.forename: Adrian Y
authors.initials: AY
authors.lastname: Kohut
authors.affiliation: Department of Surgery, Division of Colorectal Surgery, Drexel University College of Medicine, 245 North 15th Street, Suite 7150 NCB, Philadelphia, PA 19102, USA.
authors.forename: David E
authors.initials: DE
authors.lastname: Stein
authors.affiliation: Department of Surgery, Division of Colorectal Surgery, Drexel University College of Medicine, 245 North 15th Street, Suite 7150 NCB, Philadelphia, PA 19102, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Sensenig
authors.affiliation: Department of Surgery, Division of Colorectal Surgery, Drexel University College of Medicine, 245 North 15th Street, Suite 7150 NCB, Philadelphia, PA 19102, USA. Electronic address: jpoggio@msn.com.
authors.forename: Juan L
authors.initials: JL
authors.lastname: Poggio
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical / Q000401:mortality; D015415:Biomarkers / Q000097:blood; D003082:Colectomy / Q000401:mortality*; D003404:Creatinine / Q000097:blood; D016208:Databases, Factual; D017558:Elective Surgical Procedures / Q000401:mortality*; D005260:Female; D006801:Humans; D007082:Ileum / Q000601:surgery*; D007676:Kidney Failure, Chronic / Q000097:blood / Q000401:mortality*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016737:Proctocolectomy, Restorative / Q000401:mortality; D058996:Quality Improvement; D012007:Rectum / Q000601:surgery*; D012307:Risk Factors
chemical_list: D015415:Biomarkers; D003404:Creatinine
keywords: American College of Surgeons National Surgical Quality Improvement Program; Colorectal surgery; End-stage renal disease; Mortality; Serum creatinine