title: Risk factors of breast cancer in kyzylorda oblast of Kazakhstan: a case-control study.
abstract: BACKGROUND
  Breast cancer in Kazakhstan and its Kyzylorda oblast is the most prevalent cancer in women and features increasing trends of incidence. The aim of study was to reveal risk factors for breast cancer among women of Kyzylorda oblast of Kazakhstan.
  
  
  METHODS
  A hospital-based case-control study was conducted at Kyzylorda oblast Oncology Center, including 114 cases of breast cancer and 196 controls. Binary logistic regression analysis was performed.
  
  
  RESULTS
  Social and behavioral risk factors for breast cancer were evaluated, among which unfavorable living conditions, chronic stress, unilateral breastfeeding, breastfeeding less than 3 months and over 2 years, abortions, and hereditary predisposition were found to be related with increased breast cancer risk. Breastfeeding for 6-24 months was found to be protective.
  
  
  CONCLUSIONS
  The findings may have significant impact on activity planning aimed towards breast cancer reduction among women in Kazakhstan.
authors.affiliation: Kazakhstan School of Public Health of Ministry of Health, Almaty, Kazakhstan E-mail : u.toleutai@gmail.com.
authors.forename: Ulpan
authors.initials: U
authors.lastname: Toleutay
authors.forename: Vitaly
authors.initials: V
authors.lastname: Reznik
authors.forename: Zhanna
authors.initials: Z
authors.lastname: Kalmatayeva
authors.forename: Kastytis
authors.initials: K
authors.lastname: Smigelskas
mesh_terms: D000028:Abortion, Induced / Q000706:statistics & numerical data; D000022:Abortion, Spontaneous; D000328:Adult; D001942:Breast Feeding / Q000706:statistics & numerical data*; D001943:Breast Neoplasms / Q000453:epidemiology / Q000209:etiology*; D016022:Case-Control Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007623:Kazakhstan / Q000453:epidemiology; D008019:Life Style; D011379:Prognosis; D012307:Risk Factors; D013315:Stress, Psychological; D055815:Young Adult