title: Acute liver failure caused by mushroom poisoning: a case report and review of the literature.
abstract: It is estimated that there are over 5,000 species of mushrooms worldwide. Some of them are edible and some are poisonous due to containing significant toxins. In more than 95% of mushroom toxicity cases, poisoning occurs as a result of misidentification of the mushroom by an amateur mushroom hunter. The severity of mushroom poisoning may vary, depending on the geographic location where the mushroom is grown, growth conditions, the amount of toxin delivered, and the genetic characteristics of the mushroom. Amanita phalloides is the most common and fatal cause of mushroom poisoning. This mushroom contains amanitins, which are powerful hepatotoxins that inhibit RNA polymerase II in liver. Mushroom poisoning is a relatively rare cause of acute liver failure. A 63-year-old male patient was admitted to the emergency room with weakness, nausea, vomiting, and diarrhea. He reported ingesting several wild mushrooms about 36 hours earlier. In this article we report a case of lethal Amanita phalloides intoxication from stored mushrooms.
authors.affiliation: Internal Medicine Department, Kayseri Training and Research Hospital, Kayseri, Turkey.
authors.forename: Abdulsamet
authors.initials: A
authors.lastname: Erden
authors.forename: Kübra
authors.initials: K
authors.lastname: Esmeray
authors.forename: Hatice
authors.initials: H
authors.lastname: Karagöz
authors.forename: Samet
authors.initials: S
authors.lastname: Karahan
authors.forename: Hasan Hüseyin
authors.initials: HH
authors.lastname: Gümüşçü
authors.forename: Mustafa
authors.initials: M
authors.lastname: Başak
authors.forename: Ali
authors.initials: A
authors.lastname: Cetinkaya
authors.forename: Deniz
authors.initials: D
authors.lastname: Avcı
authors.forename: Orhan Kürşat
authors.initials: OK
authors.lastname: Poyrazoğlu
keywords: Amanita phalloides; acute liver failure; mushroom; poisoning