title: [Development of meniscus biomaterial].
abstract: Meniscus is one of the most important tissues in knee joint from the biomechanical point of view. Meniscus injury is well known to cause osteoarthritis. At moment, there is a limitation of operative repair procedure especially for the meniscus injury with defect. We have been investigating the development of meniscus biomaterials. Meniscus substitute made of atelo-collagen was proved to be one of the candidates of meniscus biomaterial by our experiments using human cell culture, three-dimensional cultured tissue, and animal study.
authors.affiliation: Department of Health and Sport Sciences, Medicine for Sports and Performing Arts, Osaka University Graduate School of Medicine, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Nakata
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Mae
authors.forename: Yasukazu
authors.initials: Y
authors.lastname: Yonetani
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Matsuo
authors.forename: Yuta
authors.initials: Y
authors.lastname: Tachibana
authors.forename: Takashi
authors.initials: T
authors.lastname: Kanamoto
authors.forename: Keisuke
authors.initials: K
authors.lastname: Kita
authors.forename: Hideki
authors.initials: H
authors.lastname: Yoshikawa
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D002478:Cells, Cultured; D003094:Collagen; D006801:Humans; D008592:Menisci, Tibial; D020370:Osteoarthritis, Knee / Q000209:etiology; D019736:Prostheses and Implants; D011474:Prosthesis Design; D000070600:Tibial Meniscus Injuries
chemical_list: D001672:Biocompatible Materials; C059821:atelocollagen; D003094:Collagen