title: [Acute cytomegalovirus infection-associated hemophagocytic syndrome in a patient treated with azathioprine].
abstract: The authors present the case of a 21-year-old woman with ulcerative colitis. Azathioprine treatment was complicated with pancytopenia and septic shock. Acute cytomegalovirus infection related to the immunosuppressive therapy, resulting in hemophagocytosis syndrome and neutropenic fever was diagnosed. Recovery was achieved by the administration of parenteral ganciclovir, broad spectrum antibiotic and complex intensive care.
authors.affiliation: Petz Aladár Megyei Oktató Kórház Onkoradiológiai Osztály Győr Vasvári Pál u. 2-4. 9024.
authors.forename: Tamás
authors.initials: T
authors.lastname: Kullmann
authors.forename: Tibor
authors.initials: T
authors.lastname: Kárász
authors.forename: Béla
authors.initials: B
authors.lastname: Gartner
authors.forename: Akos
authors.initials: A
authors.lastname: Issekutz
authors.forename: Attila
authors.initials: A
authors.lastname: Oláh
authors.forename: István
authors.initials: I
authors.lastname: Rácz
mesh_terms: D000998:Antiviral Agents / Q000008:administration & dosage; D001379:Azathioprine / Q000008:administration & dosage / Q000009:adverse effects*; D003093:Colitis, Ulcerative / Q000188:drug therapy* / Q000473:pathology; D003113:Colonoscopy; D003131:Combined Modality Therapy; D003422:Critical Care / Q000379:methods*; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000276:immunology; D064147:Febrile Neutropenia / Q000628:therapy / Q000821:virology; D005260:Female; D015774:Ganciclovir / Q000008:administration & dosage; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D007262:Infusions, Intravenous; D051359:Lymphohistiocytosis, Hemophagocytic / Q000188:drug therapy / Q000628:therapy* / Q000821:virology*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D007166:Immunosuppressive Agents; D001379:Azathioprine; D015774:Ganciclovir
keywords: CMV; azathioprin; azathioprine; gyulladásos bélbetegség; haemophagocytosis szindróma; hemophagocytic syndrome; inflammatory bowel disease