title: Inflammation and macular oedema after pars plana vitrectomy.
abstract: Cystoid macular oedema (CMO) is a major cause of reduced vision following intraocular surgery. Although the aetiology of CMO is not completely clarified, intraocular inflammation is known to play a major role in its development. The macula may develop cytotoxic oedema when the primary lesion and fluid accumulation occur in the parenchymatous cells (intracellular oedema) or vasogenic oedema when the primary defect occurs in the blood-retinal barrier and leads to extracellular fluid accumulation (extracellular oedema). We report on the mechanisms of CMO formation after pars plana vitrectomy and associated surgical procedures and discuss possible therapeutic approaches.
authors.affiliation: Second University of Naples, Via Pansini 5, 80100 Napoli, Italy.
authors.forename: Vito
authors.initials: V
authors.lastname: Romano
authors.forename: Martina
authors.initials: M
authors.lastname: Angi
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Scotti
authors.forename: Renata
authors.initials: R
authors.lastname: del Grosso
authors.forename: Davide
authors.initials: D
authors.lastname: Romano
authors.forename: Francesco
authors.initials: F
authors.lastname: Semeraro
authors.forename: Paolo
authors.initials: P
authors.lastname: Vinciguerra
authors.forename: Ciro
authors.initials: C
authors.lastname: Costagliola
authors.forename: Mario R
authors.initials: MR
authors.lastname: Romano
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001813:Blood-Retinal Barrier; D002387:Cataract Extraction / Q000009:adverse effects; D006801:Humans; D007249:Inflammation / Q000473:pathology*; D007908:Lens, Crystalline / Q000601:surgery; D008269:Macular Edema / Q000209:etiology* / Q000276:immunology* / Q000517:prevention & control; D012160:Retina / Q000601:surgery; D012828:Silicones / Q000737:chemistry; D014605:Uveitis / Q000601:surgery; D014821:Vitrectomy / Q000009:adverse effects*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D012828:Silicones