title: Characterizing 5-methylcytosine in the mammalian epitranscriptome.
abstract: The post-transcriptional modification 5-methylcytosine (m5C) occurs in a wide range of coding and non-coding RNAs. We describe transcriptome-wide approaches to capture the global m5C RNA methylome. We also discuss the potential functions of m5C in RNA and compare them to 6-methyladenosine modifications.
authors.forename: Shobbir
authors.initials: S
authors.lastname: Hussain
authors.forename: Jelena
authors.initials: J
authors.lastname: Aleksic
authors.forename: Sandra
authors.initials: S
authors.lastname: Blanco
authors.forename: Sabine
authors.initials: S
authors.lastname: Dietmann
authors.forename: Michaela
authors.initials: M
authors.lastname: Frye
mesh_terms: D044503:5-Methylcytosine / Q000378:metabolism*; D000241:Adenosine / Q000031:analogs & derivatives / Q000378:metabolism; D000818:Animals; D002478:Cells, Cultured; D044127:Epigenesis, Genetic; D006801:Humans; D051379:Mice; D012323:RNA Processing, Post-Transcriptional; D022661:RNA, Untranslated / Q000378:metabolism; D059467:Transcriptome
chemical_list: D022661:RNA, Untranslated; D044503:5-Methylcytosine; C010223:N-methyladenosine; D000241:Adenosine