title: Lacrimal gland marginal zone lymphoma: regression after treatment of chronic hepatitis C virus infection: case report and review of the literature.
abstract: A 43-year-old woman was first admitted to the ophthalmology clinic with the complaint of a mass compressing the right eye. Based on clinical and laboratory examinations she was diagnosed as having marginal zone lymphoma (MZL) of the right lacrimal gland in addition to hepatitis C virus (HCV) infection. After the treatment for HCV infection with pegylated interferon plus ribavirin, a radiographic response of the MZL was obtained; she remains in remission through thirty months of clinical follow-up. In this case, the treatment of HCV infection led to regression of MZL suggesting the necessity of testing for HCV infection and treatment of the HCV infection should be highly considered in all HCV-positive patients with MZL's.
authors.affiliation: Department of Gastroenterology, Adnan Menderes University, School of Medicine, Turkey.
authors.forename: Adil
authors.initials: A
authors.lastname: Coskun
authors.forename: Ozden
authors.initials: O
authors.lastname: Yukselen
authors.forename: Vahit
authors.initials: V
authors.lastname: Yukselen
authors.forename: A Onder
authors.initials: AO
authors.lastname: Karaoglu
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D005134:Eye Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use; D007765:Lacrimal Apparatus / Q000000981:diagnostic imaging; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D011092:Polyethylene Glycols / Q000627:therapeutic use; D011994:Recombinant Proteins / Q000627:therapeutic use; D012074:Remission Induction; D012254:Ribavirin / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D000998:Antiviral Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D011092:Polyethylene Glycols; D012254:Ribavirin; C417083:peginterferon alfa-2b