title: Polyethylene glycol as a novel solvent for extraction of crude polysaccharides from Pericarpium granati.
abstract: Polyethylene glycol aqueous solution (PEGs), an environmentally friendly solvent was used, for the first time, to develop an extraction method for crude polysaccharides from pericarpium granati with ultrasonic-microwave-assisted extraction (UMAE). Compared with other extraction solvents, PEGs, especially PEG400, displayed a higher extraction yield. The extraction conditions were an ultrasonic power of 240 W, a microwave power of 365 W, a PEG400 concentration of 30% and a ratio of liquid to raw material of 20 mL/g, optimized by using Box-Behnken experimental design. Under these conditions, an extraction yield of 7.94 ± 0.3% (n=3) was obtained, which is about 25% higher than that with water as a solvent, and the polysaccharides content in pericarpium granati was 6.56 ± 0.01 mg/g expressed as glucose.
authors.affiliation: Key Laboratory of Ministry of Education for Medicinal Resource and Natural Pharmaceutical Chemistry, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, China.
authors.forename: Xin-Yu
authors.initials: XY
authors.lastname: Zhou
authors.forename: Rui-Lin
authors.initials: RL
authors.lastname: Liu
authors.forename: Xue
authors.initials: X
authors.lastname: Ma
authors.forename: Zhi-Qi
authors.initials: ZQ
authors.lastname: Zhang
mesh_terms: D005591:Chemical Fractionation / Q000379:methods*; D011092:Polyethylene Glycols / Q000737:chemistry*; D011134:Polysaccharides / Q000302:isolation & purification*; D012997:Solvents / Q000737:chemistry*; D014465:Ultrasonics
chemical_list: D011134:Polysaccharides; D012997:Solvents; D011092:Polyethylene Glycols
keywords: Pericarpium granati; Polyethylene glycol; Polysaccharides; Ultrasonic–microwave-assisted extraction