title: Methodological aspects of optimizing the choice of plants for creation of new drugs.
abstract: An integrative systemic model of pharmacological reaction to a phytopreparation was created as a result of conceptual structurization of facts and formalization of causal relations. The use of the new methodological approach to the choice, primary screening, and profound studies of plants for prospective addition thereof to the list of officinal medicinal plants was studied. Use of modern information technologies makes it possible to minimize the labor and time consumption and to carry out automated search, studies of new plant objects, and creation on this base of drugs with scientifically valid therapeutic efficiency.
authors.affiliation: Volgograd State Medical University, Ministry of Health and Social Development of the Russian Federation; Volgograd State Technological University, Russia. i.u.mitrofanova@yandex.ru.
authors.forename: I Yu
authors.initials: IY
authors.lastname: Mitrofanova
authors.forename: A V
authors.initials: AV
authors.lastname: Yanitskaya
authors.forename: D V
authors.initials: DV
authors.lastname: Butenko
mesh_terms: D000465:Algorithms; D003663:Decision Trees; D006801:Humans; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D012107:Research Design / Q000706:statistics & numerical data