title: [The study of spatial distribution of Helicobacter pylori infection rate in able-bodied population of Moscow in the course of medical examination of the manufacturing contingents].
abstract: Numerous studies have shown that Helicobacter pylori (H. pylori) is a leading etiologic factor in the development of chronic atrophic gastritis, one gastric ulcer and duodenal ulcer and gastric cancer. Effective prevention of gastroduodenal pathology requires the right information about its prevalence in the population and risk factors. The most reliable information can be obtained during medical examination of the able-bodied population, which provides in-depth clinical examination of contingents with the identification of asymptomatic pathology, detection of risk groups, the substantiation ofprophylactic measures and tracking their efficacy.
  
  
  METHODS
  During the clinical examination of the manufacturing contingents there was performed a study of the presence of infection Helicobacter pylori (H. pylori) in 2414 people aged 19 to 74 years. For more details on the presence of gastroduodenal pathology 991 people were examined with the use of clinical methods and interviews. The aggregation of information presented in the form of estimates for its geocoding and mapping has been made. Cluster analysis was performed.
  
  
  RESULTS
  H. pylori infection was diagnosed in 2,182 people accounting for 90.4% out of 2414 examined cases. Infections occurred equally in males--91.7% and females--89.6%. The risk of development of gastroduodenal pathology in individuals infected with H. pylori is 4.4 times greater than the risk in seronegative individuals (95%, confidence interval 1.9-6.4). Cluster analysis revealed a statistically significant clusters for the strata with a prevalence of 100% (X2 = 45.5204) and below 50% of infection rate (X2 = 7.36). It is in prospect to analyze in more detail the data relating to these areas in order to identify the factors contributing to the different degree of infection rate of residents, including the assessment of drinking water.
authors: Iu A
authors: IuA
authors: Rakhmanin
authors: I E
authors: IE
authors: Zykova
authors: T P
authors: TP
authors: Fedichkina
authors: L G
authors: LG
authors: Solenova
authors: S V
authors: SV
authors: German
authors: A V
authors: AV
authors: Modestova
authors: V A
authors: VA
authors: Kislitsin
mesh_terms: D000328:Adult; D000368:Aged; D003938:Diagnostic Techniques, Digestive System; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis / Q000453:epidemiology*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D007221:Industry; D008297:Male; D008875:Middle Aged; D009031:Moscow / Q000453:epidemiology; D016272:Occupational Health; D015995:Prevalence; D012307:Risk Factors; D014505:Urban Population; D055815:Young Adult