title: Renal replacement therapy due to type 1 diabetes; time trends during 1995-2010--a Swedish population based register study.
abstract: BACKGROUND
  End stage renal disease (ESRD), is the most severe complication of diabetes mellitus. This population-based study analysed time trends for start of renal replacement therapy (RRT) due to type 1 diabetes compared to type 2 diabetes and other diagnoses.
  
  
  METHODS
  We used data on patients who were registered 1995-2010 in the Swedish Renal Registry, a nationwide register covering 95 % of all patients with uraemia. The patients were analysed according to their original kidney disease. The incidence was analysed by calendar year, age at start of RRT and gender.
  
  
  RESULTS
  Of 17389 patients who were registered, 1833 had type 1 diabetes; 65% were men. The mean age at onset of RRT for patients with type 1 diabetes was 52.8 years which increased by more than 3 years over the studied period. The number of patients in need of RRT due to type 1 diabetes decreased, while RRT due to type 2 diabetes increased during the period studied.
  
  
  CONCLUSIONS
  The overall incidence of RRT in Sweden is rather constant over the years but the need for RRT in type 1 diabetes patients decreased and patients with type 1 diabetes tend to become older at onset of RRT.
authors: Department of Clinical Sciences, Pediatrics, Umeå University, Umeå; Department of Internal Medicine, Ryhov County Hospital, Jönköping. Electronic address: cecilia.toppe@lj.se.
authors: Cecilia
authors: C
authors: Toppe
authors: Department of Internal Medicine, Ryhov County Hospital, Jönköping.
authors: Anna
authors: A
authors: Möllsten
authors: Diaverum Renal Services Group, Lund, & Swedish Renal Registry, Jönköping.
authors: Staffan
authors: S
authors: Schön
authors: Department of Internal Medicine, Ryhov County Hospital, Jönköping.
authors: Anders
authors: A
authors: Jönsson
authors: Department of Internal Medicine, Ryhov County Hospital, Jönköping.
authors: Gisela
authors: G
authors: Dahlquist
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000453:epidemiology / Q000628:therapy*; D003928:Diabetic Nephropathies / Q000453:epidemiology / Q000628:therapy*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007676:Kidney Failure, Chronic / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012042:Registries / Q000706:statistics & numerical data; D017582:Renal Replacement Therapy / Q000706:statistics & numerical data; D013548:Sweden / Q000453:epidemiology; D055815:Young Adult
keywords: Diabetes mellitus; Incidence; Nephropathy; Renal replacement therapy