title: "Green" functionalization of magnetic nanoparticles via tea polyphenol for magnetic resonance/fluorescent dual-imaging.
abstract: Tea polyphenol serves as an environmentally friendly ligand-exchange molecule to synthesize multifunctional metal-doped superparamagnetic iron oxide nanoparticles via a catechol-metal coordination interaction. The resultant particles not only exhibit excellent hydrophilicity and protein adsorption resistance, but also are applicable as magnetic resonance/fluorescent dual-imaging probes due to their high T₂ relaxivity, autofluorescence and large cellular uptake.
authors: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan 610064, China. zwgu@scu.edu.cn wuyao@scu.edu.cn.
authors: Wen
authors: W
authors: Jiang
authors: Kuilin
authors: K
authors: Lai
authors: Kexia
authors: K
authors: Liu
authors: Rui
authors: R
authors: Xia
authors: Fabao
authors: F
authors: Gao
authors: Yao
authors: Y
authors: Wu
authors: Zhongwei
authors: Z
authors: Gu
mesh_terms: D000327:Adsorption; D001672:Biocompatible Materials / Q000737:chemistry; D003287:Contrast Media / Q000737:chemistry; D005290:Ferric Compounds / Q000737:chemistry; D055772:Green Chemistry Technology; D006367:HeLa Cells; D006801:Humans; D008024:Ligands; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D053768:Metal Nanoparticles / Q000737:chemistry; D008670:Metals / Q000737:chemistry; D008856:Microscopy, Fluorescence; D053758:Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D055095:Optics and Photonics; D059808:Polyphenols / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013662:Tea / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D003287:Contrast Media; D005290:Ferric Compounds; D008024:Ligands; D008670:Metals; D059808:Polyphenols; D013662:Tea; C000499:ferric oxide