title: A case of pulmonary alveolar proteinosis treated with whole lung lavage.
abstract: Pulmonary alveolar proteinosis represents a rare syndrome characterized by the accumulation of proteinaceous phospholipid-laden material in the alveoli. This leads to impaired gas exchange and arterial hypoxemia of varying degrees. The diagnosis is confirmed by lung biopsy. Sequential whole-lung lavage (WLL) first described in 1963 is the standard of care. We report a case of a male diagnosed of having pulmonary alveolar proteinosis (PAP) on transbroncial lung biopsy (TBLB). He was treated with sequential WLL (Left followed by right, Left being more involved on chest X-ray) followed by recombinant GM-CSF, with good result.
authors: Department of Respiratory, Critical Care and Sleep Medicine, Indraprastha Apollo Hospital, New Delhi, India.
authors: Avdhesh
authors: A
authors: Bansal
authors: Vikas
authors: V
authors: Sikri
keywords: Granulocyte macrophage colony stimulating factor; Trans Bronchial Lung Biopsy; pulmonary alveolar proteinosis; whole-lung lavage