title: Determination of polybrominated diphenyl ethers and polychlorinated biphenyls in fishery and aquaculture products using sequential solid phase extraction and large volume injection gas chromatography/tandem mass spectrometry.
abstract: A new method was developed to determine polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in fishery and aquaculture products. Samples were extracted by an accelerated solvent extraction system and cleaned up by sequential solid phase extraction (SPE) including dispersive SPE (D-SPE) and tandem SPE. PBDEs and PCBs were analyzed by a large-volume injection gas chromatography triple quadrupole mass spectrometry (LVI-GC-QqQ-MS/MS). Good linearity (R(2)≥0.9958) was achieved. Method detection limits (MDLs) were 0.16-3.3pgg(-1) (wet weight, ww) for PBDEs and 0.13-0.97pgg(-1)ww for PCBs. Mean recoveries were 60-140% with relative standard deviations (RSDs) of less than 20% in weever fish, scallop and shrimp samples spiked at a lower level of 13-31pgg(-1)ww and a higher level of 50-125pgg(-1)ww. Certified reference materials were analyzed with acceptable results. The method reduced solvent consumption, analytical time and labor, and is suitable for the routine analysis of PBDEs and PCBs in fishery and aquaculture products.
authors: Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan West Road, Shanghai 200336, China.
authors: Dasheng
authors: D
authors: Lu
authors: Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan West Road, Shanghai 200336, China.
authors: Yuanjie
authors: Y
authors: Lin
authors: Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan West Road, Shanghai 200336, China.
authors: Chao
authors: C
authors: Feng
authors: California Department of Public Health, Richmond, CA 94804, USA.
authors: Dongli
authors: D
authors: Wang
authors: Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan West Road, Shanghai 200336, China.
authors: Xinlei
authors: X
authors: Qiu
authors: Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan West Road, Shanghai 200336, China.
authors: Yu'e
authors: Y
authors: Jin
authors: Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan West Road, Shanghai 200336, China.
authors: Libei
authors: L
authors: Xiong
authors: School of Life Science, Shanghai University, Shanghai 200444, China.
authors: Ying
authors: Y
authors: Jin
authors: Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan West Road, Shanghai 200336, China. Electronic address: gqwang@scdc.sh.cn.
authors: Guoquan
authors: G
authors: Wang
mesh_terms: D000818:Animals; D005396:Fish Products / Q000032:analysis*; D005398:Fisheries / Q000379:methods; D005399:Fishes; D055768:Halogenated Diphenyl Ethers / Q000032:analysis*; D064088:Hazard Analysis and Critical Control Points / Q000379:methods*; D057230:Limit of Detection; D011078:Polychlorinated Biphenyls / Q000032:analysis*; D052616:Solid Phase Extraction / Q000379:methods*; D053719:Tandem Mass Spectrometry / Q000379:methods; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D055768:Halogenated Diphenyl Ethers; D014874:Water Pollutants, Chemical; D011078:Polychlorinated Biphenyls
keywords: Food safety; LVI-GC–QqQ-MS/MS; POPs; Tandem SPE