title: [Biomarkers in clinical immunology].
abstract: In a current perspective of individualized medicine, biomarkers appear as a simple and readily available aid to assist clinicians in the identification and monitoring of diseases whose diagnosis is difficult. Basically, we know the limited performance of medical history and of clinical examination; therefore, the use of laboratory tests is often seen as the panacea to solve the clinical enigma. The purpose of this article is to analyze a few biomarkers commonly processed in the immunology laboratory (AAN, ANCA, anti-tTG, rheumatoid factor and anti-CCP) and to review the principle, the usefulness and the performance of these tests in specific clinical situations. We will see that, far from supplanting history and physical examination, these immunological biomarkers take their full value as a supplement to clinical information!
authors: Service de médecine interne, Département de médecine, CHUV, 1011 Lausanne. agnes.pardon@chuv.ch
authors: A
authors: A
authors: Pardon
authors: V
authors: V
authors: Aubert
authors: P-A
authors: PA
authors: Bart
mesh_terms: D001323:Autoantibodies / Q000276:immunology*; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000276:immunology; D015415:Biomarkers / Q000032:analysis*; D019411:Clinical Laboratory Techniques; D006801:Humans; D007159:Immunologic Tests / Q000379:methods*; D057285:Precision Medicine / Q000379:methods
chemical_list: D001323:Autoantibodies; D015415:Biomarkers