title: Serum metabolic profiles of pregnant women with burdened obstetrical history.
abstract: The content of low-molecular-weight components in blood serum was studied by tandem mass-spectrometry in pregnant women. Serum metabolic profiles of patients with a grave obstetrical history were detected. The most significant changes were observed for the concentrations of low-molecular-weight substances involved in glucogenesis and β-oxidation processes and in metabolic chains involving carbohydrates, carnitines, amino acids, and lipids.
authors: BioClinicum Research and Development Center; Research Institute of Pathology and Pathophysiology, the Russian Academy of Medical Sciences; V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, the Ministry of Health and Social Development of the Russian Federation, Moscow, Russia. n.seniavina@bioclinicum.com.
authors: S A
authors: SA
authors: Khaustova
authors: N V
authors: NV
authors: Senyavina
authors: A G
authors: AG
authors: Tonevitsky
authors: O V
authors: OV
authors: Eremina
authors: S V
authors: SV
authors: Pavlovich
mesh_terms: D000022:Abortion, Spontaneous / Q000097:blood*; D000596:Amino Acids / Q000097:blood; D015415:Biomarkers / Q000097:blood; D002331:Carnitine / Q000031:analogs & derivatives / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D006601:Hexoses / Q000097:blood; D006801:Humans; D010713:Phosphatidylcholines / Q000097:blood; D011247:Pregnancy; D013109:Sphingomyelins / Q000097:blood
chemical_list: D000596:Amino Acids; D015415:Biomarkers; D006601:Hexoses; D010713:Phosphatidylcholines; D013109:Sphingomyelins; C116917:acylcarnitine; D002331:Carnitine