title: [Nonallergic hypersensitivity to environmental factors].
abstract: The prevalence and severity of manifestations of non-allergic hypersensitivity to chemical environmental factors pose the question about the need to study the mechanisms of its formation in population. It should be borne in mind that, in the absence of immunological mechanisms of formation of the mentioned state, the term "chemical sensitization" must be replaced by the term "non-allergic hypersensitivity." The investigation of this problem should permit to reduce the risk of formation of different types of hypersensitivity in population.
authors: Iu A
authors: IuA
authors: Rakhmanin
authors: V N
authors: VN
authors: Fedoseeva
authors: A K
authors: AK
authors: Makovetskaia
authors: T G
authors: TG
authors: Fedoskova
mesh_terms: D004781:Environmental Exposure / Q000009:adverse effects*; D006632:Histamine / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D007073:Immunoglobulin E / Q000096:biosynthesis / Q000276:immunology; D015289:Leukotrienes / Q000276:immunology; D008407:Mast Cells / Q000276:immunology; D060149:Tetraspanin 30 / Q000276:immunology
chemical_list: C554586:CD63 protein, human; D015289:Leukotrienes; D060149:Tetraspanin 30; D007073:Immunoglobulin E; D006632:Histamine