title: Is "intra-operating room" thromboelastometry useful in liver transplantation? A case-control study in 303 patients.
abstract: Coagulation monitoring during liver transplantation (LT) is, even today, fundamental to reduce blood loss during surgery. Thromboelastometry (TEM) is a proven technique for controlling the various parameters that influence coagulation. However, there are no studies linking "intra-operating room" TEM (orTEM) with LT outcomes. We describe a case-control study in 303 liver graft recipients analyzing variables associated with operative complications and long-term LT outcomes. The results showed that orTEM reduced the use of blood products in patients with Model for End-Stage Liver Disease scores of ≥ 21, retransplantation, and high surgical difficulty and important intraoperative bleeding. In addition, results in survival and postoperative complications were better when orTEM was used. In conclusion, we confirm that use of orTEM is associated with less use of blood products and a lower rate of complications after LT.
authors: Liver Transplant Unit, Sevilla, Spain. Electronic address: jmalamom@hotmail.com.
authors: J-M
authors: JM
authors: Alamo
authors: A
authors: A
authors: León
authors: P
authors: P
authors: Mellado
authors: C
authors: C
authors: Bernal
authors: L M
authors: LM
authors: Marín
authors: C
authors: C
authors: Cepeda
authors: G
authors: G
authors: Suárez
authors: J
authors: J
authors: Serrano
authors: J
authors: J
authors: Padillo
authors: M-Á
authors: MÁ
authors: Gómez
mesh_terms: D001777:Blood Coagulation; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001803:Blood Transfusion; D016022:Case-Control Studies; D006085:Graft Survival; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects* / Q000401:mortality; D016343:Monitoring, Intraoperative / Q000379:methods*; D011183:Postoperative Complications / Q000517:prevention & control; D011237:Predictive Value of Tests; D012307:Risk Factors; D016019:Survival Analysis; D013916:Thrombelastography; D013997:Time Factors; D016896:Treatment Outcome