title: Effects of erythrocyte microvesicles on the coagulation process stages.
abstract: We studied the effect of erythrocyte microvesicles on various stages of platelet-free autoplasma coagulation process. The erythrocyte microvesicles not only exhibited procoagulant activity, but also produced a pronounced anticoagulant effect by inhibiting fibrin formation process. The effects of microvesicles isolated from erythrocytes after 24- and 48-hour cell storage on plasma coagulation were different. The hemocoagulation effects of the "light" and "heavy" microvesicles were studied.
authors: Nizhniy Novgorod Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Russia. levin@unn.ac.ru.
authors: G Ya
authors: GY
authors: Levin
authors: E G
authors: EG
authors: Sukhareva
authors: M N
authors: MN
authors: Egorikhina
mesh_terms: D001777:Blood Coagulation; D055252:Cell-Derived Microparticles / Q000502:physiology*; D004912:Erythrocytes / Q000502:physiology*; D006801:Humans; D011517:Prothrombin Time