title: The case for de-escalation in antimicrobial therapy: time to change our strategy in the management of septic shock?
authors: Infectious Diseases Division, Santa Maria Misericordia Hospital, Udine, Italy.
authors: Matteo
authors: M
authors: Bassetti
authors: Emergency and Intensive Care Department, Centro Hospitalar Sao Joao, Porto Faculty of Medicine, University of Porto, Porto, Portugal.
authors: José-Artur
authors: JA
authors: Paiva
authors: Institute of Healthcare Associated Infection, University of the West of Scotland-University Hospital Crosshouse, 56A Lister Street, Kilmarnock, KA2 0BB, Ayrshire, UK. robert.masterton@uws.ac.uk.
authors: Robert G
authors: RG
authors: Masterton
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000188:drug therapy*; D009503:Neutropenia / Q000188:drug therapy*; D018805:Sepsis / Q000188:drug therapy*; D012772:Shock, Septic / Q000401:mortality*
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents