title: Osteoarthritis: Targeting Rac1 via microparticle-based drug delivery system protects OA cartilage in vivo.
authors: Sarah
authors: S
authors: Onuora
mesh_terms: D000634:Aminoquinolines / Q000494:pharmacology*; D000818:Animals; D002358:Cartilage, Articular / Q000187:drug effects* / Q000503:physiopathology; D004195:Disease Models, Animal; D016503:Drug Delivery Systems; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D007270:Injections, Intra-Articular; D051379:Mice; D008863:Microspheres; D010003:Osteoarthritis / Q000188:drug therapy* / Q000503:physiopathology; D011743:Pyrimidines / Q000494:pharmacology*; D020830:rac1 GTP-Binding Protein / Q000037:antagonists & inhibitors* / Q000502:physiology
chemical_list: D000634:Aminoquinolines; D004791:Enzyme Inhibitors; C487513:NSC 23766; D011743:Pyrimidines; C107953:RAC1 protein, human; D020830:rac1 GTP-Binding Protein