title: [Hilar cholangiocarcinoma: The number of positive nodes and positive node/total node ratio is a significant prognostic factor for survival].
abstract: BACKGROUND
  Surgical treatment of hilar cholangiocarcinoma remains a challenge. Multiple prognostic factors have been proposed. The number of positive nodes and the ratio between positive lymph node and total lymph node (G+/Gt) are considered by some authors as the most important factor.
  
  
  METHODS
  We analyzed a series of 58 patients with Klatskin tumors. We evaluated the prognostic factors and survival with emphasis on the prognostic impact of the number of positive nodes and its relation to total lymph nodes.
  
  
  RESULTS
  Resectability was 78% with a 5-year survival of 32%. The median number of nodes examined was 9.5. No significant differences were found in several of the proposed prognostic factors. The presence of 2 or more positive nodes or a ratio G+/Gt ≥ 0.2 were found to be poor prognostic factors.
  
  
  CONCLUSIONS
  The relationship between positive lymph nodes and total lymph nodes and the number of positive lymph nodes are important prognostic factors.
authors: Servicio de Cirugía, Hospital Florencio Díaz, Córdoba, Argentina.
authors: Gustavo Adrián
authors: GA
authors: Nari
authors: Master en Técnicas Quirúrgicas Endoscópicas, Universidad Autónoma, Barcelona, España.
authors: Oscar Germán
authors: OG
authors: Palacios
authors: Unidad de Cirugía hepato-bilio-pancreática, Servicio de Cirugía, Hospital Josep Trueta, Gerona, España.
authors: Santiago
authors: S
authors: Lopez-Ben
authors: Unidad de Cirugía hepato-bilio-pancreática, Servicio de Cirugía, Hospital Josep Trueta, Gerona, España.
authors: Maite
authors: M
authors: Albiol
authors: Unidad de Cirugía hepato-bilio-pancreática, Servicio de Cirugía, Hospital Josep Trueta, Gerona, España.
authors: Laia
authors: L
authors: Falgueras
authors: Unidad de Cirugía hepato-bilio-pancreática, Servicio de Cirugía, Hospital Josep Trueta, Gerona, España.
authors: Ernesto
authors: E
authors: Castro-Gutierrez
authors: Unidad de Cirugía hepato-bilio-pancreática, Servicio de Cirugía, Hospital Josep Trueta, Gerona, España.
authors: Joan
authors: J
authors: Figueras
mesh_terms: D000368:Aged; D001650:Bile Duct Neoplasms / Q000401:mortality* / Q000473:pathology*; D005260:Female; D006500:Hepatic Duct, Common; D006801:Humans; D018285:Klatskin Tumor / Q000401:mortality* / Q000556:secondary*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D015996:Survival Rate
keywords: Colangiocarcinoma hiliar; Estado ganglionar; Factores pronósticos; Hilar cholangiocarcinoma; Lymph node status; Prognostic factors; Surgical treatment; Tratamiento quirúrgico.