title: Glucocorticoid rhythm renders female mice more daring.
abstract: Glucocorticoids, which have been implied in mood modulation, display robust diurnal oscillations in the blood. But does their circadian rhythm regulate mood swings? Ikeda et al. now identify a paracrine signaling pathway in the adrenal cortex that potentiates the daily amplitude of plasma glucocorticoids and renders female mice braver.
authors: Department of Molecular Biology, Sciences III, University of Geneva, 1211 Geneva, Switzerland. Electronic address: gianpaolo.rando@unige.ch.
authors: Gianpaolo
authors: G
authors: Rando
authors: Ueli
authors: U
authors: Schibler
mesh_terms: D000818:Animals; D001007:Anxiety / Q000378:metabolism*; D002940:Circadian Rhythm; D005260:Female; D005938:Glucocorticoids / Q000378:metabolism*; D006801:Humans; D008297:Male; D054387:Receptors, CXCR / Q000378:metabolism*
chemical_list: C501897:Cmkor1 protein, mouse; D005938:Glucocorticoids; D054387:Receptors, CXCR