title: [Cutaneous infiltratiton by chronic myelononocytic leukemia: presentation of three cases].
abstract: Leukemia cutis refers to cutaneous infiltration by malignant hematopoietic cells. Its clinical manifestations are highly variable and biopsy is required for confirmation. We present three cases of patients with persistent monocytosis and skin lesions whose diagnosis was chronic myelomonocytic leukemia. The biopsy of skin lesions showed a dermal infiltration by atypical myelocytes and monocytes. Immunohistochemical study was positive for CD68. These findings were compatible with cutaneous infiltration by chronic myelomonocytic leukemic cells.
authors: Complejo Asistencial Universitario de Leon.
authors: Camino
authors: C
authors: Prada Garcia
authors: Pedro
authors: P
authors: Sanchez Sambucety
authors: Manuel Ángel
authors: MÁ
authors: Rodriguez Prieto
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001374:Azacitidine / Q000627:therapeutic use; D003561:Cytarabine / Q000627:therapeutic use; D017809:Fatal Outcome; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D015477:Leukemia, Myelomonocytic, Chronic / Q000188:drug therapy / Q000473:pathology*; D017254:Leukemic Infiltration / Q000473:pathology*; D008297:Male; D012867:Skin / Q000473:pathology*
chemical_list: D000970:Antineoplastic Agents; D003561:Cytarabine; D001374:Azacitidine; D006918:Hydroxyurea