title: Conservative treatment for interstitial monochorionic twin pregnancy: case report and review of the published work.
abstract: Interstitial pregnancy is considered one of the most hazardous types of ectopic pregnancies, with a mortality rate of 2-2.5%. We describe a case of a viable monochorionic twin pregnancy in a 35-year-old woman successfully treated with systemic methotrexate associated with bilateral uterine arteries' embolization. β-hCG was undetectable 67 days after the first administration of methotrexate and the ultrasonography performed on day 67 showed the remnant of the gestational sac in the right uterine horn, a thin endometrium and a normal myometrial vascularization. Conservative treatment allowed us to avoid surgical treatment and to preserve the patient's fertility.
authors: Department of Obstetrics, Gynaecology and Neonatology, University of Parma, Parma, Italy.
authors: Roberto
authors: R
authors: Berretta
authors: Carla
authors: C
authors: Merisio
authors: Andrea
authors: A
authors: Dall'Asta
authors: Carla
authors: C
authors: Verrotti
authors: Martino
authors: M
authors: Rolla
authors: Stefano
authors: S
authors: Bruni
authors: Alberto
authors: A
authors: Bacchi Modena
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000009:adverse effects; D000028:Abortion, Induced / Q000009:adverse effects*; D000328:Adult; D003131:Combined Modality Therapy / Q000009:adverse effects; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects; D011247:Pregnancy; D065167:Pregnancy, Interstitial / Q000601:surgery / Q000628:therapy*; D059285:Pregnancy, Twin; D016896:Treatment Outcome; D055357:Uterine Artery Embolization / Q000009:adverse effects
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate
keywords: interstitial pregnancy; monochorionic twin pregnancy; uterine artery embolization