title: Multiple giant vulvar syringoma: an extraordinary report.
abstract: A 26 year-old woman presented with asymptomatic multiple skin-colored eruptions affecting the vulva. She claimed that the lesions had started at the age of 15. The eruptions have been increasing in size and extent since her presentation. There was a family history of similar eruptions around the eyes of one of her sisters. Examination of the skin surface was marked by the presence of multiple, 2- to 3-cm firm, skin-colored, nodules on the labia majora (Figure 1). They were bilateral and symmetrical. One of the lesions was excised, and histopathologic serial sections were prepared and stained with hematoxylin and eosin. Sections showed clusters of small comma-shaped ducts lined by 2 cell-thick epithelium surrounded by a fibrotic stroma. Solid strands of basophilic epithelial cells independent of ducts were documented in the dermis (Figure 2). Accordingly, a diagnosis of syrangoma was made.
authors: Skin Disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. sadeghian@sdlrc.mui.ac.ir
authors: Giti
authors: G
authors: Sadeghian
authors: Hengameh
authors: H
authors: Ziaei
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D013544:Sweat Gland Neoplasms / Q000175:diagnosis* / Q000473:pathology; D018252:Syringoma / Q000175:diagnosis* / Q000473:pathology; D014846:Vulvar Neoplasms / Q000175:diagnosis* / Q000473:pathology