title: Filiform polyposis: A benign entity? Case report and literature review.
abstract: Filiform polyposis (FP) is a distinctive and unusual form of benign non syndromic polyposis that is occasionally encountered in the colon of patients with inflammatory bowel disease (IBD) history. FP is characterized by one to hundreds, slender, arborizing, vermiform projections in the colon lined by normal or inflammatory colonic mucosa. Only rare cases without history or evidence of IBD have been reported. In those cases, the sigmoid colon was the most common location and none of them showed dysplasia or malignancy neither at first evaluation nor during follow-up. In this report, we present the first case of FP associated with six adenomas developed on filiform polyps and invasive adenocarcinoma in the right colon of a 54 year-old man without a past medical history of IBD.
authors: Pathology Department, Academic Hospital, Reims, France. Electronic address: camille.boulagnon@gmail.com.
authors: Camille
authors: C
authors: Boulagnon
authors: Pathology Department, Academic Hospital, Reims, France.
authors: Jean-François
authors: JF
authors: Jazeron
authors: Digestive Surgery Department, Academic Hospital, Reims, France.
authors: Ana
authors: A
authors: Diaz-Cives
authors: Gastroenterology Department, Robert Debré Academic Hospital, Reims, France.
authors: Florent
authors: F
authors: Ehrhard
authors: Gastroenterology Department, Robert Debré Academic Hospital, Reims, France.
authors: Olivier
authors: O
authors: Bouché
authors: Pathology Department, Academic Hospital, Reims, France.
authors: Marie-Danièle
authors: MD
authors: Diebold
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D018256:Adenomatous Polyps / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D003082:Colectomy; D003110:Colonic Neoplasms / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D003111:Colonic Polyps / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D004252:DNA Mutational Analysis; D005260:Female; D006801:Humans; D044483:Intestinal Polyposis / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D008297:Male; D053842:Microsatellite Instability; D008875:Middle Aged; D009154:Mutation; D011518:Proto-Oncogene Proteins / Q000235:genetics; D016283:Proto-Oncogene Proteins p21(ras); D055815:Young Adult; D018631:ras Proteins / Q000235:genetics
chemical_list: C117307:KRAS protein, human; D011518:Proto-Oncogene Proteins; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins
keywords: Adenocarcinoma; Colon; Filiform polyposis; Inflammatory bowel disease; Intestinal polyposis