title: Detection of novel strains of cyprinid herpesvirus closely related to koi herpesvirus.
abstract: Cyprinid herpesvirus 3 (CyHV-3) or koi herpesvirus (KHV) is a devastating virus of carp. Using generic primers for the DNA polymerase and the major capsid protein genes of cyprinid herpesviruses, nucleotide sequences divergent from previously described CyHV-3 were obtained. At least 3 novel groups of putative CyHV-3-like viruses were identified, sharing 95 to 98% nucleotide identity with CyHV-3 strains. Carp carrying the CyHV-3 variants did not show clinical signs consistent with CyHV-3 infection and originated from locations with no actual CyHV-3 outbreaks. These strains might represent low- or non-pathogenic variants of CyHV-3.
authors: Central Veterinary Institute (CVI), part of Wageningen UR, PO Box 65, 8200 AB Lelystad, The Netherlands.
authors: Marc Y
authors: MY
authors: Engelsma
authors: Keith
authors: K
authors: Way
authors: Melanie J
authors: MJ
authors: Dodge
authors: Michal
authors: M
authors: Voorbergen-Laarman
authors: Valentina
authors: V
authors: Panzarin
authors: Miriam
authors: M
authors: Abbadi
authors: Mansour
authors: M
authors: El-Matbouli
authors: Helle
authors: H
authors: Frank Skall
authors: Søren
authors: S
authors: Kahns
authors: David M
authors: DM
authors: Stone
mesh_terms: D000818:Animals; D003530:Cyprinidae; D005393:Fish Diseases / Q000821:virology*; D006564:Herpesviridae / Q000145:classification / Q000235:genetics*; D006566:Herpesviridae Infections / Q000662:veterinary* / Q000821:virology; D010802:Phylogeny