title: Role of cytochrome b5 and α-tocopherol to microsomal and mitochondrial oxidation.
abstract: The existence of lipid-radical cycles in membranes as an LPO alternative has been proven. Cytochrome b5 seems to play the key role in the formation of these cycles. The functional role of lipid-radical cycles in cell metabolism, including the positive effect on microsomal and mitochondrial oxidation, is discussed.
authors: Institute of Clinical Cardiology, Russian Cardiology Research and Production Complex, the Ministry of Health and Social Development of the Russian Federation, Moscow, Russia. leon.d@mail.ru.
authors: Z S
authors: ZS
authors: Agadzhanyan
authors: A D
authors: AD
authors: Doroshchuk
authors: Yu K
authors: YK
authors: Shiryaeva
authors: L F
authors: LF
authors: Dmitriev
mesh_terms: D000255:Adenosine Triphosphate / Q000096:biosynthesis / Q000737:chemistry; D000375:Aging; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D001555:Benzene Derivatives / Q000494:pharmacology; D002352:Carrier Proteins / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D000081062:Heme-Binding Proteins; D006420:Hemeproteins / Q000378:metabolism*; D050356:Lipid Metabolism; D015227:Lipid Peroxidation / Q000502:physiology; D008099:Liver / Q000166:cytology / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism*; D008928:Mitochondria / Q000378:metabolism*; D009243:NAD / Q000737:chemistry; D010084:Oxidation-Reduction; D051381:Rats; D017208:Rats, Wistar; D017382:Reactive Oxygen Species; D024502:alpha-Tocopherol / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D001555:Benzene Derivatives; D002352:Carrier Proteins; D000081062:Heme-Binding Proteins; D006420:Hemeproteins; D017382:Reactive Oxygen Species; D009243:NAD; D000255:Adenosine Triphosphate; C015763:cumene; D024502:alpha-Tocopherol