title: Investigation of the relationship between serum hormones and pilonidal sinus disease: a cross-sectional study.
abstract: OBJECTIVE
  The aim of this cross-sectional study was to determine whether pilonidal sinus is influenced by hormones that stimulate body hair growth. Currently, there are insufficient data on the presence of hormonal abnormalities in pilonidal sinus disease.
  
  
  METHODS
  Hormone levels (including those of thyroid-stimulating hormone, follicular-stimulating hormone, luteinizing hormone, prolactin, progesterone, oestradiol, testosterone, cortisol and dehydroepiandrosterone) were measured in 39 patients with pilonodal sinus presenting between February 2013 and March 2013. The results were compared with those of 39 volunteers without this disease.
  
  
  RESULTS
  There was no statistically significant difference between men with pilonidal sinus disease (P > 0.05). The prolactin levels of women with pilonoidal sinus were significantly higher than those of women in the control group (P < 0.05).
  
  
  CONCLUSIONS
  Raised serum prolactin levels in women may be related to the development of pilonidal sinus disease.
authors: General Surgery Clinic, Elazığ Training and Research Hospital, Elazığ, Turkey.
authors: Z
authors: Z
authors: Özkan
authors: N
authors: N
authors: Aksoy
authors: S
authors: S
authors: Emir
authors: B H
authors: BH
authors: Kanat
authors: A N
authors: AN
authors: Gönen
authors: F M
authors: FM
authors: Yazar
authors: A R
authors: AR
authors: Çimen
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D003687:Dehydroepiandrosterone / Q000097:blood; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006728:Hormones / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D010864:Pilonidal Sinus / Q000097:blood*; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D055815:Young Adult
chemical_list: D006728:Hormones; D013739:Testosterone; D003687:Dehydroepiandrosterone; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D006854:Hydrocortisone
keywords: Serum hormones; pilonidal sinus; prolactin; women