title: Sleep Architecture and Mental Health Among Community-Dwelling Older Men.
abstract: OBJECTIVE
  To investigate the association of mood and anxiety symptoms with sleep architecture (the distribution of sleep stages) in community-dwelling older men.
  
  
  METHODS
  We used in-home unattended polysomnography to measure sleep architecture in older men. Men were categorized into 4 mental health categories: (a) significant depressive symptoms only (DEP+ only, Geriatric Depression Scale ≥ 6), (b) significant anxiety symptoms only (ANX+ only, Goldberg Anxiety Scale ≥ 5), (c) significant depressive and anxiety symptoms (DEP+/ANX+), or (d) no significant depressive or anxiety symptoms (DEP-/ANX-).
  
  
  RESULTS
  Compared with men without clinically significant symptomology, men with depressive symptoms spent a higher percentage of time in Stage 2 sleep (65.42% DEP+ only vs 62.47% DEP-/ANX-, p = .003) and a lower percentage of time in rapid eye movement sleep (17.05% DEP+ only vs 19.44% DEP-/ANX-, p = .0005). These differences persisted after adjustment for demographic/lifestyle characteristics, medical conditions, medications, and sleep disturbances, and after excluding participants using psychotropic medications. The sleep architecture of ANX+ or DEP+/ANX+ men did not differ from asymptomatic men.
  
  
  CONCLUSIONS
  Depressed mood in older adults may be associated with accelerated age-related changes in sleep architecture. Longitudinal community-based studies using diagnostic measures are needed to further clarify relationships among common mental disorders, aging, and sleep.
authors: Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania.
authors: Stephen F
authors: SF
authors: Smagula
authors: Department of Psychiatry, Western Psychiatric Institute and Clinic of UPMC, Pennsylvania. Department of Behavioral and Community Health Sciences, Graduate School of Public Health, University of Pittsburgh, Pennsylvania.
authors: Charles F
authors: CF
authors: Reynolds
authors: Departments of Psychiatry and Medicine, University of California San Diego, La Jolla. VA Center of Excellence for Stress and Mental Health (CESAMH), San Diego, California.
authors: Sonia
authors: S
authors: Ancoli-Israel
authors: Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla.
authors: Elizabeth
authors: E
authors: Barrett-Connor
authors: Division of Geriatrics and Aging, Columbia University, New York.
authors: Thuy-Tien
authors: TT
authors: Dam
authors: Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla.
authors: Jan M
authors: JM
authors: Hughes-Austin
authors: Division of Epidemiology & Community Health, University of Minnesota, Minneapolis.
authors: Misti
authors: M
authors: Paudel
authors: Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
authors: Susan
authors: S
authors: Redline
authors: Research Institute, California Pacific Medical Center, San Francisco.
authors: Katie L
authors: KL
authors: Stone
authors: Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania. jcauley@edc.pitt.edu.
authors: Jane A
authors: JA
authors: Cauley
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D001007:Anxiety / Q000453:epidemiology / Q000503:physiopathology*; D015897:Comorbidity; D003863:Depression / Q000453:epidemiology / Q000503:physiopathology*; D006801:Humans; D057187:Independent Living; D008297:Male; D017286:Polysomnography; D012894:Sleep Stages / Q000502:physiology*; D014481:United States / Q000453:epidemiology
keywords: Aging; Anxiety; Depression; Epidemiology; Sleep architecture