title: Infection of small ruminants and their red blood cells with Theileria annulata schizonts.
abstract: Theileria annulata, the causative agent of tropical theileriosis, is a protozoan parasite that also causes lymphoproliferative diseases in cattle. In vivo, parasitized cells undergo clonal expansion and infiltrate both the lymphoid and non-lymphoid tissues of the infected host. To determine whether the small ruminants and their red blood cells (RBCs) were invaded by T. annulata schizonts or not, T. annulata schizonts were used to infect bovine, ovine and caprine RBCs in vitro, and sheep and goats in vivo. The results showed that the schizonts infected bovine, ovine and caprine RBCs in vitro, but not sheep and goats, which showed only an increase in body temperature and no development of piroplasms. To our knowledge, this is the first report of infection of small ruminants and their RBCs by T. annulata schizonts.
authors: State Key Laboratory of Veterinary Etiological Biology, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Key Laboratory of Veterinary Parasitology of Gansu Province, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Science, Xujiaping 1, Lanzhou, Gansu 730046, PR China.
authors: Youquan
authors: Y
authors: Li
authors: State Key Laboratory of Veterinary Etiological Biology, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Key Laboratory of Veterinary Parasitology of Gansu Province, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Science, Xujiaping 1, Lanzhou, Gansu 730046, PR China.
authors: Zhijie
authors: Z
authors: Liu
authors: State Key Laboratory of Veterinary Etiological Biology, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Key Laboratory of Veterinary Parasitology of Gansu Province, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Science, Xujiaping 1, Lanzhou, Gansu 730046, PR China.
authors: Jifei
authors: J
authors: Yang
authors: State Key Laboratory of Veterinary Etiological Biology, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Key Laboratory of Veterinary Parasitology of Gansu Province, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Science, Xujiaping 1, Lanzhou, Gansu 730046, PR China.
authors: Ze
authors: Z
authors: Chen
authors: State Key Laboratory of Veterinary Etiological Biology, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Key Laboratory of Veterinary Parasitology of Gansu Province, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Science, Xujiaping 1, Lanzhou, Gansu 730046, PR China.
authors: Guiquan
authors: G
authors: Guan
authors: State Key Laboratory of Veterinary Etiological Biology, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Key Laboratory of Veterinary Parasitology of Gansu Province, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Science, Xujiaping 1, Lanzhou, Gansu 730046, PR China.
authors: Qingli
authors: Q
authors: Niu
authors: State Key Laboratory of Veterinary Etiological Biology, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Key Laboratory of Veterinary Parasitology of Gansu Province, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Science, Xujiaping 1, Lanzhou, Gansu 730046, PR China.
authors: Xiao
authors: X
authors: Zhang
authors: State Key Laboratory of Veterinary Etiological Biology, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Key Laboratory of Veterinary Parasitology of Gansu Province, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Science, Xujiaping 1, Lanzhou, Gansu 730046, PR China.
authors: Jianxun
authors: J
authors: Luo
authors: State Key Laboratory of Veterinary Etiological Biology, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Key Laboratory of Veterinary Parasitology of Gansu Province, Xujiaping 1, Lanzhou, Gansu 730046, PR China; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Science, Xujiaping 1, Lanzhou, Gansu 730046, PR China. Electronic address: yinhong@caas.net.cn.
authors: Hong
authors: H
authors: Yin
mesh_terms: D000818:Animals; D002417:Cattle; D004912:Erythrocytes / Q000469:parasitology*; D015511:Goat Diseases / Q000097:blood / Q000469:parasitology*; D006041:Goats; D018512:Parasitemia / Q000469:parasitology / Q000662:veterinary; D052939:Schizonts / Q000502:physiology; D012756:Sheep; D012757:Sheep Diseases / Q000097:blood / Q000469:parasitology*; D016796:Theileria annulata / Q000502:physiology*; D013801:Theileriasis / Q000097:blood / Q000469:parasitology*
keywords: In vitro; Infection; Red blood cells (RBCs); Theileria annulata schizonts