title: A fluorescence-Raman dual-imaging platform based on complexes of conjugated polymers and carbon nanotubes.
abstract: The present study describes a flexible nanoplatform based on electrostatic assembly of conjugated polyelectrolytes (CPEs) and carboxylated multi-walled carbon nanotubes (cMWNTs). It is demonstrated that the obtained nanocomposites inherit intrinsic optical properties of CPEs and characteristic Raman vibration modes of MWNTs, providing a fluorescence-Raman dual-imaging method for intracellular tracking and locating of MWNTs. We suggest that the cellular internalization of the CPE-cMWNT nanocomposites is a surface charge-dependent process. The strengths of this nanoplatform include satisfying biocompatibility, enhanced protein-repellent property, and ease of implementation, making it available for both in vitro and in vivo applications.
authors: Department of Polymer Science & Engineering and Key Laboratory of Mesoscopic Chemistry of MOE, School of Chemistry & Chemical Engineering, Nanjing University, Nanjing, 210093, China. qdshen@nju.edu.cn.
authors: Yun
authors: Y
authors: Liu
authors: Jun
authors: J
authors: Huang
authors: Min-Jie
authors: MJ
authors: Sun
authors: Ji-Cheng
authors: JC
authors: Yu
authors: Yu-Lei
authors: YL
authors: Chen
authors: Yu-Qi
authors: YQ
authors: Zhang
authors: Shao-Jun
authors: SJ
authors: Jiang
authors: Qun-Dong
authors: QD
authors: Shen
mesh_terms: D000327:Adsorption; D000818:Animals; D001672:Biocompatible Materials; D002244:Carbon / Q000737:chemistry; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects*; D045304:Cytochromes c / Q000737:chemistry; D016503:Drug Delivery Systems; D004573:Electrolytes / Q000737:chemistry*; D006454:Hemoglobins / Q000737:chemistry; D006736:Horses; D006801:Humans; D008856:Microscopy, Fluorescence; D053761:Nanocomposites / Q000737:chemistry; D036103:Nanotechnology; D037742:Nanotubes, Carbon / Q000737:chemistry*; D055095:Optics and Photonics; D011108:Polymers / Q000737:chemistry*; D013059:Spectrum Analysis, Raman / Q000379:methods*; D055672:Static Electricity
chemical_list: D001672:Biocompatible Materials; D004573:Electrolytes; D006454:Hemoglobins; D037742:Nanotubes, Carbon; D011108:Polymers; D002244:Carbon; D045304:Cytochromes c