title: IL-17 T cells' defective differentiation in vitro despite normal range ex vivo in chronic mucocutaneous candidiasis due to STAT1 mutation.
authors: Laboratory of Transmission, Control and Immunobiology of Infections (LR11IPT02), Institut Pasteur de Tunis and University Tunis El Manar, Tunis, Tunisia.
authors: Najla
authors: N
authors: Mekki
authors: Laboratory of Transmission, Control and Immunobiology of Infections (LR11IPT02), Institut Pasteur de Tunis and University Tunis El Manar, Tunis, Tunisia.
authors: Imen
authors: I
authors: Ben-Mustapha
authors: Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Necker Medical School, INSERM U980 and University Paris Descartes, Paris, France.
authors: Luyan
authors: L
authors: Liu
authors: Department of Dermatology, CHU Farhat Hached, Sousse, Tunisia.
authors: Lobna
authors: L
authors: Boussofara
authors: St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, New York, USA.
authors: Satoshi
authors: S
authors: Okada
authors: St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, New York, USA.
authors: Sophie
authors: S
authors: Cypowyj
authors: Department of Dermatology, CHU Farhat Hached, Sousse, Tunisia.
authors: Najet
authors: N
authors: Ghariani
authors: Department of Dermatology, CHU Farhat Hached, Sousse, Tunisia.
authors: Wafa
authors: W
authors: Saidi
authors: Department of Dermatology, CHU Farhat Hached, Sousse, Tunisia.
authors: Mohamed
authors: M
authors: Denguezli
authors: Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Necker Medical School, INSERM U980 and University Paris Descartes, Paris, France; St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, New York, USA.
authors: Jean-Laurent
authors: JL
authors: Casanova
authors: Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Necker Medical School, INSERM U980 and University Paris Descartes, Paris, France.
authors: Anne
authors: A
authors: Puel
authors: Laboratory of Transmission, Control and Immunobiology of Infections (LR11IPT02), Institut Pasteur de Tunis and University Tunis El Manar, Tunis, Tunisia. Electronic address: ridha.barbouche@pasteur.rns.tn.
authors: Mohamed-Ridha
authors: MR
authors: Barbouche
mesh_terms: D001120:Arginine / Q000737:chemistry; D002178:Candidiasis, Chronic Mucocutaneous / Q000235:genetics* / Q000378:metabolism; D002454:Cell Differentiation; D002648:Child; D005260:Female; D006579:Heterozygote; D006801:Humans; D007930:Leucine / Q000737:chemistry; D008213:Lymphocyte Activation; D009154:Mutation; D020125:Mutation, Missense; D020641:Polymorphism, Single Nucleotide; D050794:STAT1 Transcription Factor / Q000235:genetics*; D017422:Sequence Analysis, DNA; D015398:Signal Transduction; D058504:Th17 Cells / Q000166:cytology*; D014416:Tunisia
chemical_list: D050794:STAT1 Transcription Factor; C494079:STAT1 protein, human; D001120:Arginine; D007930:Leucine