title: A newborn with neurocutaneous melanocytosis and Dandy-Walker malformation.
abstract: BACKGROUND
  Neurocutaneous melanocytosis is a rare congenital dysplasia of the neuroectodermal melanocyte precursor cells that leads to proliferation of melanin-producing cells in the skin and leptomeninges.
  
  
  METHODS
  We describe a newborn with a giant congenital melanocytic nevus on his back, buttocks, and thighs. His brain magnetic resonance imaging study revealed bilateral T1 hyperintense lesions in the cerebellum and in the amygdala, hydrocephalus, and a Blake's pouch cyst, consistent with neurocutaneous melanocytosis and Dandy-Walker malformation.
  
  
  CONCLUSIONS
  Neurocutaneous melanocytosis has a wide clinical spectrum that includes hydrocephalus, epilepsy, cranial nerve palsy, increased intracranial pressure, and sensorimotor deficits.
authors: Radiology, University Hospitals Leuven, and Department of Imaging and Pathology, KU Leuven, Belgium.
authors: Jens
authors: J
authors: De Cock
authors: Dermatology, University Hospitals Leuven, and Department of Oncology, KU Leuven, Belgium.
authors: Julie
authors: J
authors: Snauwaert
authors: Radiology, GZA Ziekenhuizen Sint-Augustinus, Wilrijk, Belgium.
authors: Walter
authors: W
authors: Van Rompaey
authors: Dermatology, University Hospitals Leuven, and Department of Oncology, KU Leuven, Belgium.
authors: Marie-Anne
authors: MA
authors: Morren
authors: Radiology, University Hospitals Leuven, and Department of Imaging and Pathology, KU Leuven, Belgium. Electronic address: philippe.demaerel@uzleuven.be.
authors: Philippe
authors: P
authors: Demaerel
mesh_terms: D001415:Back / Q000473:pathology; D001921:Brain / Q000473:pathology; D003616:Dandy-Walker Syndrome / Q000150:complications* / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D008548:Melanosis / Q000150:complications* / Q000473:pathology*; D020752:Neurocutaneous Syndromes / Q000150:complications* / Q000473:pathology*; D009508:Nevus, Pigmented / Q000150:complications* / Q000473:pathology*
keywords: Dandy-Walker malformation; congenital nevi; melanocytosis; neurocutaneous syndromes