title: [Biomarkers associated with dyspnea and chest pain: which cinical utility?].
abstract: Dyspnea and chest pain are typical reasons for consultations. biomarkers (CRP, procalcitonin, NT-proBNP, troponins, D-dimers) can have an interest for the diagnosis, the prognosis and the follow-up of several pathologies. There are however numerous pitfalls and limitations between the discovery of a biomarker and the utility in clinical practice. It is essential to always estimate a pre-test probability based on an attentive history and a careful physical examination, to know the intrinsic and extrinsic qualities of a test, and to determine a threshold of care. A biomarker should be used only if it modifies the patient's care and if it brings him a benefit compared to the patient who has no biomarker.
authors: Service de médecine interne, CHUV, 1011 Lausanne. olivier.lamy@chuv.ch
authors: O
authors: O
authors: Lamy
mesh_terms: D000369:Aged, 80 and over; D015415:Biomarkers / Q000032:analysis*; D002637:Chest Pain / Q000175:diagnosis* / Q000209:etiology; D019937:Diagnostic Techniques and Procedures; D004417:Dyspnea / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D005791:Patient Care / Q000379:methods; D011379:Prognosis
chemical_list: D015415:Biomarkers