title: The emerging problem of biological treatment in migrant and travelling populations: it is time to extend guidelines for the screening of infectious diseases.
abstract: The use of biological agents in the treatment of rheumatic diseases has been widely associated with an increased risk of reactivation of several latent infections. National and international guidelines recommend screening for infectious diseases before starting these drugs. In Western countries screening is limited to latent tuberculosis infection, HIV and viral hepatitis. However, the increasing globalisation and the remarkable number of migrating and travelling people worldwide make this approach no longer adequate. The Italian and Spanish Societies of Rheumatology and Tropical Medicine wish to issue a warning about the need to improve awareness of doctors about the risk of reactivation of infectious tropical diseases in migrant or travelling patients who undergo biological therapy. Thus, the Italian and Spanish Societies are now planning to issue specific recommendations, based on a multidisciplinary contribution and a systematic review of the literature, for screening and follow-up of active and latent chronic infections in candidate patients for biological agents, taking into account the patient's area of origin and risk of infectious diseases.
authors: Division of Infectious and Tropical Diseases AOUC, Department of Experimental and Clinical Medicine, Italian Society of Tropical Medicine (SIMET), University of Florence, Florence, Italy.
authors: F
authors: F
authors: Bartalesi
authors: A
authors: A
authors: Bartoloni
authors: Z
authors: Z
authors: Bisoffi
authors: M
authors: M
authors: Spinicci
authors: F
authors: F
authors: Giménez Sánchez
authors: J
authors: J
authors: Muñoz
authors: P
authors: P
authors: Richi
authors: G
authors: G
authors: Minisola
authors: S
authors: S
authors: Muñoz-Fernandez
authors: M
authors: M
authors: Matucci-Cerinic
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use; D003141:Communicable Diseases / Q000175:diagnosis*; D017408:Guidelines as Topic; D006801:Humans; D055985:Latent Tuberculosis; D008403:Mass Screening; D012216:Rheumatic Diseases / Q000188:drug therapy; D014171:Transients and Migrants
chemical_list: D018501:Antirheumatic Agents
keywords: Anti-TNF; DMARDs (biologic); Rheumatoid Arthritis; Spondyloarthritis; Tuberculosis