title: Antifouling and antimicrobial polymer membranes based on bioinspired polydopamine and strong hydrogen-bonded poly(N-vinyl pyrrolidone).
abstract: A facile and versatile approach for the preparation of antifouling and antimicrobial polymer membranes has been developed on the basis of bioinspired polydopamine (PDA) in this work. It is well-known that a tightly adherent PDA layer can be generated over a wide range of material surfaces through a simple dip-coating process in dopamine aqueous solution. The resulting PDA coating is prone to be further surface-tailored and functionalized via secondary treatments because of its robust reactivity. Herein, a typical hydrophobic polypropylene (PP) porous membrane was first coated with a PDA layer and then further modified by poly(N-vinyl pyrrolidone) (PVP) via multiple hydrogen-bonding interactions between PVP and PDA. Data of water contact angle measurements showed that hydrophilicity and wettability of the membranes were significantly improved after introducing PDA and PVP layers. Both permeation fluxes and antifouling properties of the modified membranes were enhanced as evaluated in oil/water emulsion filtration, protein filtration, and adsorption tests. Furthermore, the modified membranes showed remarkable antimicrobial activity after iodine complexation with the PVP layer. The PVP layer immobilized on the membrane had satisfying long-term stability and durability because of the strong noncovalent forces between PVP and PDA coating. The strategy of material surface modification reported here is substrate-independent, and applicable to a broad range of materials and geometries, which allows effective development of materials with novel functional coatings based on the mussel-inspired surface chemistry.
authors: MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University , Hangzhou 310027, P. R. China.
authors: Jinhong
authors: J
authors: Jiang
authors: Liping
authors: L
authors: Zhu
authors: Lijing
authors: L
authors: Zhu
authors: Hongtao
authors: H
authors: Zhang
authors: Baoku
authors: B
authors: Zhu
authors: Youyi
authors: Y
authors: Xu
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D006859:Hydrogen / Q000737:chemistry; D006860:Hydrogen Bonding; D057927:Hydrophobic and Hydrophilic Interactions; D007211:Indoles / Q000737:chemistry*; D009821:Oils / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D011205:Povidone / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects; D013499:Surface Properties; D014867:Water / Q000737:chemistry; D017155:Wettability
chemical_list: D000890:Anti-Infective Agents; D007211:Indoles; D009821:Oils; D011108:Polymers; C568283:polydopamine; D014867:Water; D006859:Hydrogen; D011205:Povidone