title: Regional analysis of femoral head perfusion following displaced fractures of the femoral neck.
abstract: OBJECTIVE
  To assess regional variations in the arterial and venous blood supply to the femoral head following displaced fracture of the femoral neck using dynamic contrast enhanced (DCE)-MRI quadrant analysis.
  
  
  METHODS
  A total of 27 subjects with displaced femoral neck fractures were enrolled in the study. Quadrant specific DCE-MRI perfusion analysis was performed on a 1.5 Tesla MRI scanner. Simultaneous imaging of control and displaced fractured hips was done for comparison.
  
  
  RESULTS
  Quadrant specific decreases were found in the arterial (A (0.52 versus 0.27; P = 5.7E-13), Akep (1.0/min(-1) versus 0.41/min(-1) ; P = 1.3E-9) and venous (kel (0.05/min(-1) versus -0.02/min(-1) ; P = 5.1E-5) supply to the femoral head between control and injured sides using a two-factor analysis of variance test. The fractional perfusion (initial area under the curve) in the supero/inferolateral quadrants was 49% min/54% min, in the supero/inferomedial quadrants was 43% min/46% min and for the total femoral head was 39% min on the fracture versus control sides.
  
  
  CONCLUSIONS
  Quadrant specific decreases in arterial and venous perfusion on the fracture side were observed when compared with control.
authors: Department of Radiology, Weill Cornell Medical College, New York, New York, USA.
authors: Jonathan P
authors: JP
authors: Dyke
authors: Lionel E
authors: LE
authors: Lazaro
authors: Carolyn M
authors: CM
authors: Hettrich
authors: Keith D
authors: KD
authors: Hentel
authors: David L
authors: DL
authors: Helfet
authors: Dean G
authors: DG
authors: Lorich
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D005265:Femoral Neck Fractures / Q000150:complications*; D005270:Femur Head / Q000098:blood supply*; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA
keywords: DCE-MRI; MRI; bone perfusion; dynamic contrast enhanced MRI; femoral neck fracture