title: Image quality of ultra-low-dose dual-source CT angiography using high-pitch spiral acquisition and iterative reconstruction in young children with congenital heart disease.
abstract: BACKGROUND
  Obtaining diagnostic CT image quality with ultra-low radiation dose in young children with congenital heart disease remains challenging.
  
  
  OBJECTIVE
  We evaluated the feasibility and image quality of prospectively electrocardiogram (ECG)-triggered high-pitch spiral acquisition with iterative reconstruction for pediatric cardiovascular CT angiography.
  
  
  METHODS
  Sixty-two consecutive pediatric patients younger than 2 years with congenital heart disease underwent prospectively ECG-triggered high-pitch spiral dual-source CT acquisition. Patients were randomly assigned into 2 groups: full tube current (40-70 mAs) scans with filtered back projection reconstruction (group A) and half tube current (20-35 mAs) scans with sinogram-affirmed iterative reconstruction (group B). Attenuation, noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and subjective image quality were compared between the 2 groups. Effective radiation dose was also estimated for both groups.
  
  
  RESULTS
  No significant difference was found in the attenuation, image noise, SNR, and CNR between the 2 groups in the same evaluated anatomic regions, whereas the attenuation and image noise were slightly lower, and the SNR and CNR were slightly higher in group B. No significant difference was found in subjective image quality between the 2 groups (4.27 ± 0.73 vs. 4.34 ± 0.42; P = .813). Effective dose was 0.06 ± 0.03 mSv in group B and 0.13 ± 0.04 mSv in group A, reflecting dose savings of 53.8% by using iterative reconstruction.
  
  
  CONCLUSIONS
  A combination of prospectively ECG-triggered high-pitch spiral acquisition, low tube current, and iterative reconstruction may offer diagnostic image quality in pediatric cardiovascular CT angiography with effective radiation dose < 0.1 mSv.
authors: Department of Radiology, Xijing Hospital, Fourth Military Medical University, 127# West Changle Road, Xi'an 710032, Shaanxi Province, China. Electronic address: zhengmw2007@163.com.
authors: Minwen
authors: M
authors: Zheng
authors: Department of Radiology, Xijing Hospital, Fourth Military Medical University, 127# West Changle Road, Xi'an 710032, Shaanxi Province, China.
authors: Hongliang
authors: H
authors: Zhao
authors: Department of Radiology, Xijing Hospital, Fourth Military Medical University, 127# West Changle Road, Xi'an 710032, Shaanxi Province, China.
authors: Jian
authors: J
authors: Xu
authors: Department of Radiology, Xijing Hospital, Fourth Military Medical University, 127# West Changle Road, Xi'an 710032, Shaanxi Province, China.
authors: Yongjie
authors: Y
authors: Wu
authors: Department of Radiology, Xijing Hospital, Fourth Military Medical University, 127# West Changle Road, Xi'an 710032, Shaanxi Province, China.
authors: Jian
authors: J
authors: Li
mesh_terms: D055424:Cardiac-Gated Imaging Techniques / Q000379:methods*; D002675:Child, Preschool; D017023:Coronary Angiography / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D008297:Male; D011829:Radiation Dosage; D011835:Radiation Protection / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015900:Radiography, Dual-Energy Scanned Projection / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D036542:Tomography, Spiral Computed / Q000379:methods*
keywords: Computed tomography; Congenital heart disease; High-pitch; Iterative reconstruction; Pediatric imaging; Radiation dose