title: Use of nanoclay platelets in food packaging materials: technical and cytotoxicity approach.
abstract: Two organo-modified clays for food contact applications were developed to produce hydrophobically modified montmorillonite and hence to obtain better compatibility between the biopolymer and the filler (nanoclay). These nanofillers were characterised by Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction and thermogravimetric analysis (TGA) in order to study their composition, structure and thermal stability. The fillers were used to reinforce polylactic acid (PLA) bottles, which were characterised using different techniques such as mechanical and barrier properties, morphology and thermal stability. The results were compared with conventional PLA bottles. The use of the modified clay in PLA bottles was found to lead to an improvement in mechanical and barrier properties. Finally, cytotoxicity tests were carried out with the organo-modified clays using Caco-2 and HepG2 cell lines, with uptake of neutral red as a basal cytotoxicity biomarker.
authors: a Packaging , Transport and Logistics Research Institute , C/Albert Einstein, 1, Paterna, E-46980 Valencia , Spain.
authors: M
authors: M
authors: Jorda-Beneyto
authors: N
authors: N
authors: Ortuño
authors: A
authors: A
authors: Devis
authors: S
authors: S
authors: Aucejo
authors: M
authors: M
authors: Puerto
authors: D
authors: D
authors: Gutiérrez-Praena
authors: J
authors: J
authors: Houtman
authors: S
authors: S
authors: Pichardo
authors: S
authors: S
authors: Maisanaba
authors: A
authors: A
authors: Jos
mesh_terms: D000538:Aluminum Silicates / Q000737:chemistry* / Q000633:toxicity*; D001546:Bentonite / Q000737:chemistry / Q000633:toxicity; D018938:Caco-2 Cells; D002470:Cell Survival / Q000187:drug effects; D000077215:Clay; D018857:Food Packaging / Q000379:methods*; D056945:Hep G2 Cells; D006358:Hot Temperature; D006801:Humans; D019344:Lactic Acid / Q000737:chemistry / Q000633:toxicity; D008422:Materials Testing; D046529:Microscopy, Electron, Transmission; D053761:Nanocomposites / Q000737:chemistry* / Q000633:toxicity* / Q000648:ultrastructure; D010539:Permeability; D011091:Polyesters; D011108:Polymers / Q000737:chemistry / Q000633:toxicity; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D000538:Aluminum Silicates; D011091:Polyesters; D011108:Polymers; D001546:Bentonite; D019344:Lactic Acid; C033616:poly(lactide); D000077215:Clay