title: A case of Plasmodium ovale wallikeri infection in a Chinese worker returning from West Africa.
abstract: In contrast to the gradual reduction in the number of locally transmitted malaria cases in China, the number of imported malaria cases has been increasing since 2008. Here, we report a case of a 39-year-old Chinese man who acquired Plasmodium ovale wallikeri infection while staying in Ghana, West Africa for 6 months in 2012. Microscopic examinations of Giemsa-stained thin and thick blood smears indicated Plasmodium vivax infection. However, the results of rapid diagnostic tests, which were conducted 3 times, were not in agreement with P. vivax. To further check the diagnosis, standard PCR analysis of the small-subunit rRNA gene was conducted, based on which a phylogeny tree was constructed. The results of gene sequencing indicated that this malaria is a variant of P. ovale (P. ovale wallikeri). The infection in this patient was not a new infection, but a relapse of the infection from the one that he had contracted in West Africa.
authors: Parasitic Diseases Department, Hainan Provincial Center for Disease Control and Prevention, Haikou, Hainan 570203, P. R. China.
authors: Yuchun
authors: Y
authors: Li
authors: Guangze
authors: G
authors: Wang
authors: Dingwei
authors: D
authors: Sun
authors: Feng
authors: F
authors: Meng
authors: Shigan
authors: S
authors: Lin
authors: Ximin
authors: X
authors: Hu
authors: Shanqing
authors: S
authors: Wang
mesh_terms: D000328:Adult; D001399:Azure Stains; D001483:Base Sequence; D002681:China; D016054:DNA, Protozoan / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D005869:Ghana; D006801:Humans; D008288:Malaria / Q000175:diagnosis* / Q000469:parasitology; D008297:Male; D008969:Molecular Sequence Data; D010802:Phylogeny; D041122:Plasmodium ovale / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D012008:Recurrence; D017422:Sequence Analysis, DNA; D014195:Travel
chemical_list: D001399:Azure Stains; D016054:DNA, Protozoan; D004275:DNA, Ribosomal
keywords: China; Plasmodium ovale wallikeri; case report; imported malaria