title: Budd-Chiari syndrome secondary to toxic pyrrolizidine alkaloid exposure.
abstract: In this report, we describe a case of pyrrolizidine alkaloid-related Budd-Chiari syndrome in Hong Kong. A 10-month-old boy presented with ascites, right pleural effusion, and hepatomegaly after consumption of herbal drinks for 3 months. His clinical (including imaging) features were compatible with Budd-Chiari syndrome. Budd-Chiari syndrome is a rare disease entity in paediatric patients. In our case, extensive workup performed to look for the underlying cause of Budd-Chiari syndrome was unrevealing, except for toxic pyrrolizidine alkaloid exposure in his herbal drinks.
authors: Department of Paediatrics and Adolescent Medicine, United Christian Hospital, Kwun Tong, Hong Kong.
authors: Janet S W
authors: JS
authors: Wu
authors: W T
authors: WT
authors: Poon
authors: C K
authors: CK
authors: Ma
authors: M L
authors: ML
authors: Chen
authors: K S
authors: KS
authors: Pang
authors: Tony W L
authors: TW
authors: Mak
authors: H B
authors: HB
authors: Chan
mesh_terms: D006502:Budd-Chiari Syndrome / Q000209:etiology* / Q000503:physiopathology; D006529:Hepatomegaly / Q000209:etiology / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D010936:Plant Extracts / Q000008:administration & dosage / Q000009:adverse effects*; D010996:Pleural Effusion / Q000209:etiology / Q000473:pathology; D011763:Pyrrolizidine Alkaloids / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D010936:Plant Extracts; D011763:Pyrrolizidine Alkaloids
keywords: Ascites; Budd-Chiari syndrome; Pleural effusion; Pyrrolizidine alkaloids