title: CCX-CKR expression in colorectal cancer and patient survival.
abstract: Colorectal cancer is one of the most common malignant cancers, with bad prognosis when distal metastasis occurs. The current study aimed to investigate the potential value of using CCX-CKR expression for the prognosis of colorectal cancer patients. The results showed that CCX-CKR expression was a negative predictor of cancer metastasis, and that it was positively correlated to the patients&rsquo; survival rate. Finally, we found that CCX-CKR expression in vitro could modulate cellular migration and invasion abilities, potentially via the regulation of other chemotactic factors/receptors.
authors: #The two authors contributed equally to this work.
authors: Yunxiang
authors: Y
authors: Zhu
authors: Wentao
authors: W
authors: Tang
authors: Yun
authors: Y
authors: Liu
authors: Guanghui
authors: G
authors: Wang
authors: Zhonglin
authors: Z
authors: Liang
authors: Long
authors: L
authors: Cui
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D045744:Cell Line, Tumor; D002465:Cell Movement / Q000235:genetics; D015179:Colorectal Neoplasms / Q000235:genetics* / Q000473:pathology; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000235:genetics; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D054388:Receptors, CCR / Q000096:biosynthesis* / Q000235:genetics
chemical_list: C408223:ACKR4 protein, human; D054388:Receptors, CCR