title: Improved hypertrophy of future remnant liver after portal vein embolization with plugs, coils and particles.
abstract: OBJECTIVE
  To retrospectively analyze efficacy as measured by volume gain of future remnant liver (FRL) after right portal vein embolization (PVE) using particles only versus particles and additional central plug and/or coil (CP/C) embolization.
  
  
  METHODS
  All patients who underwent PVE between July 2011 and December 2012 were retrospectively analyzed. Right PVE was performed either with particle-only (PO) embolization or additional CP/C embolization. All enrolled patients underwent computed tomography or magnetic resonance imaging before PVE and surgery. The images were used for volumetry of the FRL.
  
  
  RESULTS
  Of 75 patients, 40 had PO and 35 CP/C embolization. Age, sex, and tumor entities did not differ significantly between the two groups. Tumor entities included cholangiocarcinoma (n = 52), metastasis from colorectal cancer (n = 14), hepatocellular carcinoma (n = 2), and others (n = 7). Time from PVE to preoperative imaging was similar in both groups. FRL volume before PVE was 329 ± 121 ml in the PO group and 333 ± 135 ml in the CP/C group, and 419 ± 135 ml and 492 ± 165 ml before operation. The average percentage volume gain was significantly higher in the CP/C group than in the PO group, with 53.3 ± 34.5 % versus 30.9 ± 28.8 % (p = 0.002).
  
  
  CONCLUSIONS
  Right PVE with additional CP/C embolization leads to a significantly higher gain in FRL volume than embolization with particles alone.
authors: Department of Diagnostic and Interventional Radiology, Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany, dominik.geisel@charite.de.
authors: Dominik
authors: D
authors: Geisel
authors: Maciej
authors: M
authors: Malinowski
authors: Maciej-Janusz
authors: MJ
authors: Powerski
authors: Joost
authors: J
authors: Wüstefeld
authors: Victoria
authors: V
authors: Heller
authors: Timm
authors: T
authors: Denecke
authors: Martin
authors: M
authors: Stockmann
authors: Bernhard
authors: B
authors: Gebauer
mesh_terms: D003287:Contrast Media; D004621:Embolization, Therapeutic / Q000295:instrumentation / Q000379:methods*; D005260:Female; D019786:Gadolinium DTPA; D006529:Hepatomegaly / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D008113:Liver Neoplasms / Q000150:complications / Q000601:surgery*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011169:Portal Vein; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D003287:Contrast Media; C073590:gadolinium ethoxybenzyl DTPA; D019786:Gadolinium DTPA