title: Genetic mutations in Gorlin-Goltz syndrome.
abstract: Gorlin-Goltz syndrome is a rare multisystemic disease inherited in a dominant autosomal at a high level of penetrance and variable expressiveness. It is mainly characterized by basal cell carcinoma, odontogenic keratocyst and skeletal anomalies. Diagnosis is based upon established major and minor clinical and radiographic criteria and gene mutation analysis. This article presents a case of Gorlin-Goltz syndrome, its genetic predisposition, diagnosis and management.
authors: Department of Pedodontics, Mamatha Dental College, Khammam, Andhra Pradesh, India.
authors: Muthumula
authors: M
authors: Daneswari
authors: Mutjumula Swamy Ranga
authors: MS
authors: Reddy
keywords: Gorlin-Goltz syndrome; Nevoid basal cell carcinoma; odontogenic keratocyst; palmar plantar pits