title: Preoperative factors associated with red blood cell transfusion in hip fracture patients.
abstract: BACKGROUND
  Red blood cell (RBC) transfusion is a frequently used treatment in patients admitted with a fractured hip, but the use remains an area of much debate. The aim of this study was to determine preoperative factors associated with the risk of receiving a red blood cell transfusion in hip fracture patients.
  
  
  METHODS
  The study included 986 consecutive hip fracture patients (aged 60 years or above). The patients were identified from a database of all hip fracture patients admitted to Bispebjerg University Hospital. Data for the database are collected via chart review and data extraction from the hospitals laboratory system, public registries and from the Capital Region Blood Bank Database.
  
  
  RESULTS
  Overall transfusion rate was 58.7 %. The univariate analyses showed that transfusion rate was higher among women (p = 0.004), older patients (p < 0.0001), patients with high ASA scores (p < 0.0001), patients with more severe fractures (p < 0.0001), patients with lower admission haemoglobin levels (p < 0.0001), patients not admitted from own home (p = 0.02) and patients taking aspirin (p = 0.007) or other platelet inhibitors (p = 0.01) on admission. In the multivariate analysis, increasing age, ASA ≥3, being admitted from own home, extracapsular fractures, decreasing admission haemoglobin and use of platelet inhibitors were all significantly associated with the risk of receiving a RBC transfusion.
  
  
  CONCLUSIONS
  Several readily available preoperative factors in the form of age, residence, ASA, admission haemoglobin, medication and type of fracture were independently associated with the likelihood of receiving a red blood cell transfusion in patients admitted with a fractured hip.
authors: Department of Orthopaedic Surgery, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark, christianmedom@gmail.com.
authors: Christian Medom
authors: CM
authors: Madsen
authors: Henrik Løvendahl
authors: HL
authors: Jørgensen
authors: Astrid
authors: A
authors: Norgaard
authors: Troels
authors: T
authors: Riis
authors: Christopher
authors: C
authors: Jantzen
authors: Ole Birger
authors: OB
authors: Pedersen
authors: Benn Rønnow
authors: BR
authors: Duus
authors: Jes Bruun
authors: JB
authors: Lauritzen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003718:Denmark; D017707:Erythrocyte Transfusion / Q000706:statistics & numerical data*; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006620:Hip Fractures / Q000097:blood* / Q000601:surgery / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care / Q000379:methods / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D006454:Hemoglobins