title: OXIDATIVE STRESS RESPONSE TO SHORT DURATION BOUT OF SUBMAXIMAL AEROBIC EXERCISE IN HEALTHY YOUNG ADULTS.
abstract: OBJECTIVE
  The purpose of this study was to investigate the oxidative stress response to a short duration bout of submaximal exercise in a cohort of healthy young adults.
  
  
  METHODS
  15 apparently healthy college age males and females completed a modified Bruce-protocol treadmill test to 75-80% of their heart rate reserve. Blood samples collected immediately before (pre-exercise), immediately after, 30, 60 and 120 minutes post-exercise were assayed for total antioxidant capacity (TAC), superoxide disumutase (SOD), thiobarbituric acid-reactive substances (TBARS), and protein carbonyls (PC).
  
  
  RESULTS
  SOD activity was significantly increased from pre-exercise levels at 30 minutes (77%), 60 minutes (33%), and 120 minutes (37%) post-exercise. TAC levels were also significantly increased from pre-exercise levels at 60 minutes (30%) and 120 minutes (33%) post-exercise. There were no significant changes in biomarkers for reactive oxygen/nitrogen species (RONS) mediated damage (TBARS and PC) across all post-exercise time points.
  
  
  CONCLUSIONS
  In a cohort of healthy young adults, a short duration bout of submaximal aerobic exercise elicited increases in antioxidant activity/concentration, but did not evoke changes in oxidative stress-induced damage. These results may suggest that: (1) short duration bouts of submaximal aerobic exercise are sufficient to induce RONS generation; and (2) the antioxidant defense system is capable of protecting against enhanced RONS production induced by a short duration, submaximal exercise bout in healthy young adults.
authors: Hypertension, Molecular and Applied Physiology Laboratory, Department of Kinesiology, Temple University, Philadelphia, PA.
authors: K M
authors: KM
authors: Diaz
authors: D L
authors: DL
authors: Feairheller
authors: K M
authors: KM
authors: Sturgeon
authors: S T
authors: ST
authors: Williamson
authors: M D
authors: MD
authors: Brown
keywords: Submaximal exercise; antioxidants; free radicals; oxidative stress