title: A stimuli-responsive nanogel-based sensitive and selective fluorescent sensor for Cr(3+) with thermo-induced tunable detection sensitivity.
abstract: Stimuli-responsive poly(N-isopropylacrylamide) nanogel with covalently labeled rhodamine B urea derivatives (P(NIPAM-co-RhBUA)) is utilized as a sensitive fluorescent probe for Cr(3+) in aqueous solution, and its thermo-induced tunable detection capacity is investigated. At 20 °C, non-fluorescent nanogel can selectively bind with Cr(3+) over some other metal ions, leading to prominent fluorescence OFF-ON switching due to the recognition of RhBUA with Cr(3+) . Upon heating above the phase transition temperature, enhanced fluorescence intensity is observed (≈61-fold increase at 45 °C) for the nanogel in the presence of Cr(3+) , accompanied with an improved detection sensitivity, which suggest that hydrophobic microenvironment generated in the collapsed nanogel plays an active role for their detection performance.
authors: College of Materials Science and Engineering, Shenzhen University, Shenzhen, 518060, China; Institute of Advanced Materials, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, China; Key Laboratory for Advanced Materials of Ministry of Education, Department of Materials Science and Engineering, Tsinghua University, Beijing, 100084, China.
authors: Xuejuan
authors: X
authors: Wan
authors: Haiyang
authors: H
authors: Liu
authors: Shen
authors: S
authors: Yao
authors: Tianqi
authors: T
authors: Liu
authors: Youwei
authors: Y
authors: Yao
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D002857:Chromium / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D015394:Molecular Structure; D000080385:Nanogels; D011092:Polyethylene Glycols / Q000138:chemical synthesis / Q000737:chemistry*; D011094:Polyethyleneimine / Q000138:chemical synthesis / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry; D012680:Sensitivity and Specificity; D013696:Temperature
chemical_list: D000180:Acrylic Resins; D005456:Fluorescent Dyes; D000080385:Nanogels; D012235:Rhodamines; C413692:polyethylene glycol polyethyleneimine nanogel; D002857:Chromium; C052970:poly-N-isopropylacrylamide; D011092:Polyethylene Glycols; D011094:Polyethyleneimine; C029773:rhodamine B
keywords: Cr3+ sensors; emulsion polymerization; fluorescence; nanogel; stimuli-sensitive polymers