title: Hepatoid carcinoma of the ovary without staining for alpha-fetoprotein.
abstract: Primary hepatoid carcinoma of the ovary (HCO) is a rare type of ovarian tumor that resembles hepatocellular carcinoma both histologically and immunohistochemically in its staining for alpha-fetoprotein (AFP). We describe a 51-year-old woman who presented to our hospital complaining of abdominal pain. Computed tomography scan revealed a large tumor in the pelvis. She underwent total hysterectomy and bilateral salpingo-oophorectomy with tumorectomy. A right ovarian mass measuring 9×8×6 cm was found. Histological diagnosis was hepatoid carcinoma of the right ovary. But, immunohistochemically, tumor cells were not immunoreactive for AFP and there was no elevation of serum AFP level. This is the first report of an ovarian carcinoma with typical histologic features of HCO with negative staining for AFP and normal level of serum AFP in the world.
authors: Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors: Ji-Hee
authors: JH
authors: Sung
authors: Tae Hyun
authors: TH
authors: Kim
authors: Hyang Gi
authors: HG
authors: Park
authors: Min Ji
authors: MJ
authors: Kim
authors: Byoung-Gie
authors: BG
authors: Kim
authors: Tae-Joong
authors: TJ
authors: Kim
authors: Duk-Soo
authors: DS
authors: Bae
keywords: Alpha-fetoprotein; Hepatoid carcinoma; Ovary