title: [The role of antibodies to neurotransmitters of antinociceptive system in mechanisms of neuropathic pain].
abstract: The present investigation was undertaken in order to study the role of the antibodies to neurotransmitters of antinociceptive system in pathogenesis of neuropathic pain on models of neuropathic pain. It was shown that the development of experimental neuropathic pain syndrome is accompanied with induction of autoantibodies to CABA, serotonin, noradrenalin and dopamine. It was established that the antibodies to neurotransmitters of antinociceptive system have a pronociceptive effect.
authors: S I
authors: SI
authors: Igonkina
authors: L A
authors: LA
authors: Vetrile
authors: M L
authors: ML
authors: Kukushkin
mesh_terms: D000818:Animals; D000906:Antibodies / Q000276:immunology / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D009437:Neuralgia / Q000188:drug therapy* / Q000209:etiology; D018377:Neurotransmitter Agents / Q000037:antagonists & inhibitors* / Q000276:immunology; D059225:Nociception / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000906:Antibodies; D018377:Neurotransmitter Agents