title: Perinatal- and procedure-related outcomes following radiofrequency ablation in monochorionic pregnancy.
abstract: OBJECTIVE
  We sought to assess the efficacy, complication rates, and outcomes for complex monochorionic pregnancies undergoing selective fetal reduction using radiofrequency ablation (RFA).
  
  
  METHODS
  In this prospective observational study, 100 consecutive cases of selective fetal reduction using RFA were analyzed. All cases were managed at the Centre for Fetal Care at Queen Charlotte's and Chelsea Hospital in London. Indications for offering RFA, details of the procedure, and pregnancy outcomes were collected and analyzed.
  
  
  RESULTS
  The main indications for RFA were discordant fetal anomaly and twin-twin transfusion syndrome. Overall live birth rate was 78% and the median gestation at delivery was 35.15 weeks. Delivery <32 weeks' gestation occurred in 17.9% of cases. Postprocedure abnormal antenatal magnetic resonance imaging occurred in 3% of cases. There was no statistical difference in outcomes with regard to gestation when the procedure was performed or the indication for the RFA.
  
  
  CONCLUSIONS
  RFA appears to be a reasonable option for selective fetal reduction in complex monochorionic pregnancies with an overall survival rate of 78%.
authors: Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, England, United Kingdom; Institute for Reproductive and Developmental Biology, Imperial College London, London, England, United Kingdom; Mater Research Institute, University of Queensland, Brisbane, Queensland, Australia. Electronic address: skumar@mmri.mater.org.au.
authors: Sailesh
authors: S
authors: Kumar
authors: Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, England, United Kingdom.
authors: Gowrishankar
authors: G
authors: Paramasivam
authors: Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, England, United Kingdom.
authors: Eko
authors: E
authors: Zhang
authors: Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, England, United Kingdom.
authors: Bryony
authors: B
authors: Jones
authors: Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, England, United Kingdom.
authors: Muna
authors: M
authors: Noori
authors: Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, England, United Kingdom.
authors: Tomas
authors: T
authors: Prior
authors: Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, England, United Kingdom.
authors: Akhila
authors: A
authors: Vasudeva
authors: Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, England, United Kingdom.
authors: Ruwan C
authors: RC
authors: Wimalasundera
mesh_terms: D000328:Adult; D017115:Catheter Ablation; D005260:Female; D005330:Fetofetal Transfusion / Q000401:mortality / Q000601:surgery*; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D018607:Pregnancy Reduction, Multifetal; D011446:Prospective Studies; D016019:Survival Analysis; D055815:Young Adult
keywords: fetal reduction; monochorionic; radiofrequency