title: Effects of zinc supplementation on the anthropometric measurements, lipid profiles and fasting blood glucose in the healthy obese adults.
abstract: Purpose : The aim of this study was to assess the effects of zinc supplementation on anthropometric measures, improving lipid profile biomarkers, and fasting blood glucose level in obese people.
  
  
  METHODS
  This randomized, double- blind clinical trial was carried out on 60 obese participants in the 18-45 age range for one month. The participants were randomly divided into the intervention group, who received 30 mg/d zinc gluconate, and the placebo group who received 30mg/d starch. Anthropometric measurements (body mass index (BMI), weight and waist circumference) were recorded before and at the end of study. Lipid profile biomarkers and fasting blood glucose were determined using enzymatic procedure. Analysis of Covariance (ANCOVA) test was run to compare the post-treatment values of the two groups, and t-test was conducted to compare within group changes.
  
  
  RESULTS
  Serum zinc concentration was increased significantly in intervention group (p=0.024). BMI and body weight was significantly decreased (p=0.030 and p=0.020, respectively). Lipid profile biomarkers and fating blood glucose did not change significantly but triglyceride level was significantly decreased (p=0.006) in the intervention group.
  
  
  CONCLUSIONS
  The obtained results indicate that zinc supplementation improves BMI, body weight, and triglyceride concentration without considerable effects on lipid profile and glucose level. Zinc can be suggested as a suitable supplementation therapy for obese people, but more studies are needed to verify the results.
authors: Nutrition Research Center, Faculty of Health and Nutrition, Tabriz University of Medical Science, Tabriz, Iran.
authors: Laleh
authors: L
authors: Payahoo
authors: Alireza
authors: A
authors: Ostadrahimi
authors: Majid
authors: M
authors: Mobasseri
authors: Yaser
authors: Y
authors: Khaje Bishak
authors: Nazila
authors: N
authors: Farrin
authors: Mohammad
authors: M
authors: Asghari Jafarabadi
authors: Sepide
authors: S
authors: Mahluji
keywords: Anthropometric Measurements; Fasting Blood Glucose; Lipid Profile; Obesity