title: [Comparison of short- and long-term outcome after percutaneous transluminal interventional therapy in octogenarians with coronary artery disease from radial or femoral approach].
abstract: OBJECTIVE
  To compare the short-term and long-term outcome after percutaneous coronary intervention (PCI) between transradial intervention (TRI) and transfemoral intervention (TFI) in elderly patients.
  
  
  METHODS
  From January 2005 to December 2010, 488 consecutive elderly patients ( ≥ 80 years old) were enrolled in this retrospective study. Patients were divided into TRI group (n = 235, PCIs were performed trans-radial approach) and TFI group (n = 253, PCIs were performed trans-femoral approach). Efficacy and safety data were compared between the two groups.
  
  
  RESULTS
  There were no differences in success rate of stenting, procedure time, contrast amount, rates of contrast-induced nephropathy, major adverse cardiovascular events during hospitalization, at one year follow up and at two years follow up. Lower vascular complications were associated with TRI approach[ 17.9% (42/253) vs. 26.9% (68/253) , P < 0.05], especially in TIMI major bleeding ratio [1.3% (3/235) vs. 4.7% (12/253) , P < 0.05], TIMI minor bleeding [5.1% (12/235) vs. 15.8% (40/253) , P < 0.01], and time lying in bed [3.6 (2.8-4.2)h vs. 24.4 (24.0-25.1)h, P < 0.01] and hospitalization [3.0 (3.0-4.0)d vs. 5.0 (5.0-6.0)d, P < 0.01], and higher rates of crossover approach were associated with TRI [11.5% (27/235) vs. 2.0(5/253) , P < 0.01].
  
  
  CONCLUSIONS
  TRI is as feasible, safe and effective as TFI in elderly patients during short-term and long-term follow up, and TRI is associated with higher rates of crossover approach.
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Wei
authors: W
authors: You
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China. Email: yefei@medmail.com.cn.
authors: Fei
authors: F
authors: Ye
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Shao-liang
authors: SL
authors: Chen
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Jun-jie
authors: JJ
authors: Zhang
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Nai-liang
authors: NL
authors: Tian
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Song
authors: S
authors: Lin
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Zhi-zhong
authors: ZZ
authors: Liu
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Rong
authors: R
authors: Wang
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Jing
authors: J
authors: Kan
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Tian
authors: T
authors: Xu
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Ling-ling
authors: LL
authors: Liu
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Ling
authors: L
authors: Lin
authors: Department of Cardiology,Nanjing First Hospital,Nanjing Medical University, Nanjing 210006, China.
authors: Hai-mei
authors: HM
authors: Xu
mesh_terms: D000369:Aged, 80 and over; D003324:Coronary Artery Disease / Q000628:therapy*; D005260:Female; D005263:Femoral Artery; D006801:Humans; D008297:Male; D062645:Percutaneous Coronary Intervention / Q000379:methods*; D017534:Radial Artery; D012189:Retrospective Studies; D016896:Treatment Outcome