title: iPSC-Based cell therapy: an important step forward.
abstract: Morizane et al. (2013) show that donor-matched differentiated derivatives of induced pluripotent stem cells (iPSC) do not cause an immune response after transplantation, whereas transplantation of HLA-mismatched iPSC derivatives to the same site clearly does. The importance of these results is discussed in this commentary as we assess how best to move forward with iPSC-based cell therapy.
authors: Director, NIH Center for Regenerative Medicine, 50 South Drive, Bethesda, MD 20892 USA.
authors: Mahendra
authors: M
authors: Rao
mesh_terms: D000818:Animals; D057026:Induced Pluripotent Stem Cells / Q000637:transplantation*; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D019737:Transplants / Q000276:immunology*