title: Weight loss improves serum mediators and metabolic syndrome features in android obese subjects.
abstract: Serum anti-/pro-inflammatory molecules such as adiponectin, IL-6, IL-10, and TNF-α, and metabolic syndrome (Met Syn) features in 15 android obese (6 Met Syn and 9 non-Met Syn) subjects were assessed during an 8-week weight control program. The results showed that the body mass index, weight, lean body mass, triglyceride, total cholesterol/high density lipoprotein cholesterol ratio, and TNF-α in Met Syn subjects were significantly (P < 0.05) improved. This study suggests that weight reduction in android obese subjects may be beneficial in reducing cardiovascular diseases via improving serum IL-6 and TNF-α levels, as well as Met Syn features.
authors: Taichung Veterans General Hospital, No. 160 Sec. 3, Chung-Kangn Road, Taichung 40705, Taiwan, ROC.
authors: Ching-Ya
authors: CY
authors: Chou
authors: Taichung Veterans General Hospital, No. 160 Sec. 3, Chung-Kangn Road, Taichung 40705, Taiwan, ROC.
authors: Hui-Fen
authors: HF
authors: Lang
authors: Taichung Veterans General Hospital, No. 160 Sec. 3, Chung-Kangn Road, Taichung 40705, Taiwan, ROC. Electronic address:whhsheu@mail.vghtc.gov.tw.
authors: Wanye Huey-Herng
authors: WH
authors: Sheu
authors: Department of Food Science and Biotechnology, National Chung Hsing University, 250 Kuo-Kuang Road, Taichung 40227, Taiwan, ROC. Electronic address:jinlin@nchu.edu.tw.
authors: Jin-Yuarn
authors: JY
authors: Lin
mesh_terms: D000328:Adult; D001823:Body Composition; D015992:Body Mass Index; D001835:Body Weight; D001837:Body Weights and Measures; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control*; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D004032:Diet; D015444:Exercise; D005260:Female; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000628:therapy*; D008875:Middle Aged; D056128:Obesity, Abdominal / Q000097:blood / Q000150:complications / Q000628:therapy*; D014280:Triglycerides / Q000097:blood; D014409:Tumor Necrosis Factor-alpha / Q000097:blood; D015431:Weight Loss / Q000502:physiology*; D061217:Weight Reduction Programs
chemical_list: D008076:Cholesterol, HDL; D018836:Inflammation Mediators; D015850:Interleukin-6; D014280:Triglycerides; D014409:Tumor Necrosis Factor-alpha; D002784:Cholesterol