title: Panton-Valentine leukocidin-positive Staphylococcus aureus osteomyelitis of the tibia in a 10-year-old child.
abstract: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is increasing in prevalence among asymptomatic carriers and in cases of paediatric soft-tissue infections alike. CA-MRSA may express virulence factors such as Panton-Valentine leukocidin, which makes soft-tissue and hard-tissue infections due to such organisms challenging to treat. We report a case of osteomyelitis of the proximal tibia in a 10-year-old boy and discuss its management in what is to the authors' knowledge the first case report of Panton-Valentine leukocidin-positive CA-MRSA osteomyelitis in a child in the UK.
authors: Department of Trauma and Orthopaedic Surgery, Sandwell General Hospital, West Bromwich, UK.
authors: Ross O C
authors: RO
authors: Elledge
authors: Kishore K
authors: KK
authors: Dasari
authors: Siten
authors: S
authors: Roy
mesh_terms: D001427:Bacterial Toxins; D002648:Child; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D005098:Exotoxins; D006801:Humans; D007956:Leukocidins; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D010019:Osteomyelitis / Q000175:diagnosis* / Q000382:microbiology* / Q000628:therapy; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D013977:Tibia
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin