title: Liver transplantation using low-weight recipients from a graft split program.
abstract: We present our experience with a split liver (SL) program shared with the children's liver transplantation (LT) program from 2 different hospitals in the use of partial grafts from cadaver donors in brain death. We describe an observational, retrospective study, which included patients who underwent a SL transplantation in our center between January 2006 and December 2012. Clinical variables were recorded of both donors and recipients and their data were analyzed using SPSS 19.0 software. Of a total of 204 LT, 4 (2%) patients were treated with a SL. The causes of LT were alcoholic cirrhosis in 2 cases, cryptogenic cirrhosis, and primary biliary cirrhosis (PBC). In all cases there was a temporary portocaval shunt. The confluence of the hepatic veins of the recipient was anastomosed to the donor vena cava and arterial anastomosis was performed. The reconstruction was hepato-choledochal in all cases. There were no cases of postreperfusion syndrome or vascular thrombosis and no retransplantation was necessary. Currently, 3 of the 4 cases are still alive. Death in the other patient was due to mesenteric ischemia. Our center has participated in the development of a protocol that considers the indication of this technique provided expert groups are involved in its development, regardless of hospital level. This will expand the pool of donors and partially solve the current problems with available grafting.
authors: Virgen de las Nieves University Hospital, Granada, Spain.
authors: C
authors: C
authors: San Miguel
authors: Y
authors: Y
authors: Fundora
authors: K
authors: K
authors: Muffak
authors: T
authors: T
authors: Villegas
authors: A
authors: A
authors: Becerra
authors: D
authors: D
authors: Garrote
authors: J A
authors: JA
authors: Ferrón
mesh_terms: D000714:Anastomosis, Surgical; D001835:Body Weight; D001926:Brain Death; D002102:Cadaver; D005260:Female; D006503:Hepatic Veins / Q000601:surgery; D006785:Hospitals, University; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects / Q000401:mortality; D008297:Male; D015397:Program Evaluation; D012307:Risk Factors; D013030:Spain; D013851:Thinness / Q000150:complications* / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology; D013997:Time Factors; D014019:Tissue Donors / Q000600:supply & distribution*; D016896:Treatment Outcome; D014684:Venae Cavae / Q000601:surgery; D055815:Young Adult