title: Helicenes with embedded phosphole units in enantioselective gold catalysis.
abstract: This paper discloses the first uses of phosphahelicenes as chiral ligands in transition-metal catalysis. Unlike all known helical phosphines used so far in catalysis, the phosphorus function of phosphahelicenes is embedded in the helical structure itself. This crucial structural feature originates unprecedented catalytic behaviors and efficiency. An appropriate design and fine tuning allowed both high catalytic activity and good enantiomeric excesses to be attained in the gold promoted cycloisomerizations of N-tethered 1,6-enynes and dien-ynes.
authors: Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Centre de Recherche de Gif, 91198 Gif-sur-Yvette (France).
authors: Keihann
authors: K
authors: Yavari
authors: Paul
authors: P
authors: Aillard
authors: Yang
authors: Y
authors: Zhang
authors: Frédérick
authors: F
authors: Nuter
authors: Pascal
authors: P
authors: Retailleau
authors: Arnaud
authors: A
authors: Voituriez
authors: Angela
authors: A
authors: Marinetti
keywords: asymmetric catalysis; cycloisomerization; enynes; gold; helicenes; phosphorus