title: Inheritance of resistance to neonatal E. coli diarrhoea in the pig: examination of the genetic system.
abstract: Evidence is presented that a dominant allele, S, is expressed as a receptor for K88 on the brushborder surface of the pig intestinal cell. The homozygous recessive (ss) lacks this receptor. The receptor enables K88 - positive coliforms to adhere to the gut of the piglet which they must do if they are to cause neonatal diarrhoea. The homozygous recessive is thus a disease resistant animal.A possible reason for the persistence of the dominant (susceptible) gene is given.
authors: Agricultural Research Council, Institute for Research on Animal Diseases, Compton.
authors: R A
authors: RA
authors: Gibbons
authors: R
authors: R
authors: Sellwood
authors: M
authors: M
authors: Burrows
authors: P A
authors: PA
authors: Hunter