title: ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gram-negative bacteria in hospitalized patients.
abstract: Healthcare-associated infections due to multidrug-resistant Gram-negative bacteria (MDR-GNB) are a leading cause of morbidity and mortality worldwide. These evidence-based guidelines have been produced after a systematic review of published studies on infection prevention and control interventions aimed at reducing the transmission of MDR-GNB. The recommendations are stratified by type of infection prevention and control intervention and species of MDR-GNB and are presented in the form of 'basic' practices, recommended for all acute care facilities, and 'additional special approaches' to be considered when there is still clinical and/or epidemiological and/or molecular evidence of ongoing transmission, despite the application of the basic measures. The level of evidence for and strength of each recommendation, were defined according to the GRADE approach.
authors: Division of Infectious Diseases, Department of Internal Medicine I, Tübingen University Hospital, Tübingen, Germany.
authors: E
authors: E
authors: Tacconelli
authors: M A
authors: MA
authors: Cataldo
authors: S J
authors: SJ
authors: Dancer
authors: G
authors: G
authors: De Angelis
authors: M
authors: M
authors: Falcone
authors: U
authors: U
authors: Frank
authors: G
authors: G
authors: Kahlmeter
authors: A
authors: A
authors: Pan
authors: N
authors: N
authors: Petrosillo
authors: J
authors: J
authors: Rodríguez-Baño
authors: N
authors: N
authors: Singh
authors: M
authors: M
authors: Venditti
authors: D S
authors: DS
authors: Yokoe
authors: B
authors: B
authors: Cookson
mesh_terms: D000891:Anti-Infective Agents, Local; D015373:Bacterial Typing Techniques; D002710:Chlorhexidine; D003428:Cross Infection / Q000517:prevention & control* / Q000635:transmission*; D004196:Disease Outbreaks / Q000517:prevention & control*; D024901:Drug Resistance, Multiple, Bacterial; D006090:Gram-Negative Bacteria / Q000302:isolation & purification*; D016905:Gram-Negative Bacterial Infections / Q000517:prevention & control* / Q000635:transmission*; D063373:Hand Hygiene; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D017053:Infection Control / Q000379:methods*; D012307:Risk Factors
chemical_list: D000891:Anti-Infective Agents, Local; D002710:Chlorhexidine
keywords: Acinetobacter; Burkholderia; Enterobacteriaceae; Pseudomonas; Stenotrophomonas; extended-spectrum β-lactamase; guideline; infection control; multidrug-resistant Gram-negative; outbreak