title: Standardization of Stroke Perfusion CT for Reperfusion Therapy.
abstract: With the advances in terms of perfusion imaging, the "time is brain" approach used for acute reperfusion therapy in ischemic stroke patients is slowly being replaced by a "penumbra is brain" or "imaging is brain" approach. But the concept of penumbra-guided reperfusion therapy has not been validated. The lack of standardization in penumbral imaging is one of the main contributing factors for this absence of validation. This article reviews the issues underlying the lack of standardization of perfusion-CT for penumbra imaging, and offers avenues to remedy this situation.
authors: Department of Radiology, Neuroradiology Division, University of Virginia, Box 800170, Charlottesville, VA, 22908, USA.
authors: Guangming
authors: G
authors: Zhu
authors: Patrik
authors: P
authors: Michel
authors: Weiwei
authors: W
authors: Zhang
authors: Max
authors: M
authors: Wintermark