title: Risk factors for surgical site infection in Japanese patients with ulcerative colitis: a multicenter prospective study.
abstract: OBJECTIVE
  A prospective, multicenter, observational study was performed to investigate the risk factors of surgical site infection (SSI) in patients with ulcerative colitis (UC).
  
  
  METHODS
  From 2009 to 2010, perioperative clinicopathological data were collected from patients who had undergone surgery for UC within the research period, for up to 6 consecutive months in 13 hospitals in Japan. The primary outcome was the development of SSI.
  
  
  RESULTS
  A total of 195 patients with UC who underwent colorectal surgery were enrolled. SSI was diagnosed in 38 (19.5 %) patients, in the form of incisional infection in 23 (11.8 %), organ/space infection in 16 (8.2 %), and both in 1 (0.5 %). There were no significant risk factors associated with an increased risk of development of incisional SSI. An American Society of Anesthesiologists physical status of ≥ 3 was indicated as the only significant risk factor for organ/space SSI (P = 0.02) compared with other factors, such as a neutrophil count of >100 × 10(2)/mm(3), albumin level of <3.5 g/dl, perioperative packed red blood cell transfusion, fair or poor colonic cleanliness, and therapeutic use of antibiotics.
  
  
  CONCLUSIONS
  Poor general physical status was the significant independent risk factor for organ/space SSI in patients with UC in Japan.
authors: Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan, taraki@clin.medic.mie-u.ac.jp.
authors: Toshimitsu
authors: T
authors: Araki
authors: Yoshiki
authors: Y
authors: Okita
authors: Motoi
authors: M
authors: Uchino
authors: Hiroki
authors: H
authors: Ikeuchi
authors: Iwao
authors: I
authors: Sasaki
authors: Yuji
authors: Y
authors: Funayama
authors: Kouhei
authors: K
authors: Fukushima
authors: Kitarou
authors: K
authors: Futami
authors: Kiyoshi
authors: K
authors: Maeda
authors: Tsuneo
authors: T
authors: Iiai
authors: Michio
authors: M
authors: Itabashi
authors: Kazuo
authors: K
authors: Hase
authors: Satoshi
authors: S
authors: Motoya
authors: Atsuo
authors: A
authors: Kitano
authors: Tsunekazu
authors: T
authors: Mizushima
authors: Kotaro
authors: K
authors: Maeda
authors: Minako
authors: M
authors: Kobayashi
authors: Yasuhiko
authors: Y
authors: Mohri
authors: Masato
authors: M
authors: Kusunoki
mesh_terms: D000328:Adult; D044466:Asian People; D003093:Colitis, Ulcerative / Q000601:surgery*; D013505:Digestive System Surgical Procedures; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology*; D013997:Time Factors; D016896:Treatment Outcome