title: Serotypes of Aggregatibacter actinomycetemcomitans in relation to periodontal status and geographic origin of individuals-a review of the literature.
abstract: OBJECTIVE
  Several studies have focused on the relationship among serotype distribution, ethnical status and geographic populations, and periodontal conditions. Studies that have investigated the prevalence and the distribution of A. actinomycetemcomitans serotypes and the relation between the different serotypes of the bacterium and periodontal status were reviewed.
  
  
  METHODS
  A systematic literature search for publications regarding the distribution of A. actinomycetemcomitans serotypes in subgingival samples of periodontitis patients and periodontally healthy subjects by employing polymerase chain reaction (PCR) was conducted.
  
  
  RESULTS
  From the 85 studies identified in the first analysis, only 12 met all inclusion and exclusion criteria. Clinical isolates from diverse geographic populations with different periodontal conditions were evaluated. Serotypes a, b and c were largely found, and serotype c was the most prevalent. They were isolated from various periodontal conditions, including aggressive periodontitis.
  
  
  CONCLUSIONS
  The available literature suggests that serotypes a, b, and c are globally dominant, serotypes d and e are rare, and the prevalence of the most recently identified serotype f is still unknown. It is widely accepted that distribution patterns of A. actinomycetemcomitans vary among subjects of different ethnicity and geographic regions. The correlation of different serotypes with various periodontal conditions remains unclear.
authors: Rua Monsenhor Furtado s/n, Bairro Rodolfo Teófilo, Fortaleza, Ceará, CEP 60430-170, Brazil, jandenilson@hotmail.com.
authors: J-A
authors: JA
authors: Brígido
authors: V-R-S
authors: VR
authors: da Silveira
authors: R-O
authors: RO
authors: Rego
authors: N-A-P
authors: NA
authors: Nogueira
mesh_terms: D016976:Aggregatibacter actinomycetemcomitans / Q000145:classification*; D005843:Geography; D006801:Humans; D016871:Pasteurellaceae Infections; D010512:Periodontal Index; D010518:Periodontitis / Q000382:microbiology*; D012703:Serotyping