title: Two-photon fluorescent probes for metal ions in live tissues.
abstract: Two-photon microscopy (TPM) is a new imaging tool that can detect biological targets deep inside a live tissue. To faciltate the use of TPM in biomedical research, a variety of two-photon (TP) probes for specific applications are needed. In this Forum Article, we describe the design strategy, photophysical properties, and biological imaging applications of a selection of our recent studies in the development of TP probes for metal ions. Small-molecule TP turn-on probes, organelle-targeted probes, and multicolor emissive probes for dual-color imaging are briefly reviewed.
authors: Division of Energy Systems Research, Ajou University , Suwon 443-749, Korea.
authors: Avik Ranjan
authors: AR
authors: Sarkar
authors: Dong Eun
authors: DE
authors: Kang
authors: Hwan Myung
authors: HM
authors: Kim
authors: Bong Rae
authors: BR
authors: Cho
mesh_terms: D000818:Animals; D003952:Diagnostic Imaging; D005456:Fluorescent Dyes / Q000737:chemistry; D006801:Humans; D008670:Metals / Q000032:analysis / Q000737:chemistry; D017785:Photons
chemical_list: D005456:Fluorescent Dyes; D008670:Metals