title: Usage of U7 small nuclear ribonucleic acid in gene therapy of hemoglobin D Punjab disorder: Rationale?
abstract: BACKGROUND
  Hemoglobin (Hb) D Punjab disorder is a congenital hemoglobinopathy described in India. It is a disorder due to defect in beta-globin gene.
  
  
  METHODS
  Here, the author assesses the possibility of U7.623 gene therapy for Hb D Punjab disorder. A standard bioinformatic analysis to study the effect of co-expression between nucleic acid sequence for human Hb D Punjab beta-globin chain and U7.623 was performed.
  
  
  RESULTS
  It can be seen that fully recovery of Hb function and biological process can be derived via gene ontology study.
  
  
  CONCLUSIONS
  Here, there is a rationale to use U7 small nuclear ribonucleic acid as a possible tool for gene therapy in Hb D Punjab disorder.
authors: Wiwanitkit House, Bangkhae, Bangkok-10160, Thailand.
authors: Viroj
authors: V
authors: Wiwanitkit
keywords: Hemoglobin D Punjab; U7 small nuclear ribonucleic acid; gene therapy