title: Soft contact lenses as prospective transport systems for ophthalmology.
abstract: The time course of drug adsorption and desorption, exposure of soft contact lenses in a drug solution needed for maximum saturation, and the duration of lens wearing during which the drug was transported from the lens and exhibited its therapeutic activity were studied. The possibility of using computer simulation for the choice of material, carrier for the drug (myramistin hydrochloride), was evaluated. Due to use of this method, the volume of experimental studies could be reduced and the data systematized.
authors: Belgorod State National Research University, Belgorod, Russia. novikov@bsu.edu.ru.
authors: E T
authors: ET
authors: Zhilyakova
authors: O O
authors: OO
authors: Novikov
authors: V V
authors: VV
authors: Akopova
mesh_terms: D060433:Administration, Ophthalmic; D001548:Benzalkonium Compounds / Q000008:administration & dosage; D003198:Computer Simulation; D003234:Conjunctivitis, Bacterial / Q000188:drug therapy*; D003263:Contact Lenses, Hydrophilic; D004337:Drug Carriers; D006801:Humans; D009885:Ophthalmology
chemical_list: D001548:Benzalkonium Compounds; D004337:Drug Carriers; C058048:miramistin