title: Variation in (18)F-FDG PET findings in a patient with synchronous multiple thymoma.
abstract: We herein present a case of synchronous multiple thymoma that was suspected based on the findings of positron emission tomography with fluorine-18-labeled-fluorodeoxyglucose ((18)F-FDG PET). The patient was a 70-year-old male with two similarly sized and heterogeneously enhanced masses on the right side of the anterior mediastinum on chest computed tomography. (18)F-FDG PET revealed variation in FDG accumulation between the masses, in which the maximum standardized uptake value was 4.4 in Tumor 1 and 8.7 in Tumor 2. Based on these imaging findings, the masses were suspected to be independent, likely synchronous double primary thymoma. Total thymectomy with removal of the two tumors was performed via median sternotomy. A pathological examination identified Tumor 1 as type AB thymoma and Tumor 2 as type A thymoma. This is the first reported case of synchronous multiple thymoma which was suspected based on a variation in the (18)F-FDG PET findings between the tumors.
authors: Division of Thoracic Surgery, Shizuoka Cancer Center, Shizuoka, Japan. y.chi-hi-ro@med.nagoya-u.ac.jp.|Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. y.chi-hi-ro@med.nagoya-u.ac.jp.
authors: Chihiro
authors: C
authors: Yamatani
authors: Division of Thoracic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
authors: Tomohiro
authors: T
authors: Maniwa
authors: Division of Thoracic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
authors: Shoji
authors: S
authors: Takahashi
authors: Division of Thoracic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
authors: Mitsuhiro
authors: M
authors: Isaka
authors: Division of Thoracic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
authors: Yasuhisa
authors: Y
authors: Ohde
authors: Division of Diagnostic Radiology, Shizuoka Cancer Center, Shizuoka, Japan.
authors: Masahiro
authors: M
authors: Endo
authors: Division of Diagnostic Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
authors: Takashi
authors: T
authors: Nakajima
authors: Division of Thoracic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
authors: Haruhiko
authors: H
authors: Kondo
mesh_terms: D000368:Aged; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D013934:Thymectomy; D013945:Thymoma / Q000000981:diagnostic imaging* / Q000601:surgery; D013953:Thymus Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Multiple thymoma; Positron emission tomography; Thymoma