title: [Intracranial pressure plateau waves in patients with severe traumatic brain injury].
abstract: The goal of the study was to assess frequency of plato waves, their influence on outcomes and define factors leading to plato waves. Ninety eight patients with severe traumatic brain injury (TBI) were included. Blood pressure (BP), intracranial pressure (ICP), cerebral perfusion pressure (CPP) and pressure reactivity index (Prx) were registered. Age was 34 +/- 13.6. There were 73 male and 25 female. Glasgow Coma Scale (GCS) was 6 +/- 1.4. Plato waves developed in 24 patients (group 1), 74 patients (group 2) did not have plato waves. Median of plato waves in the 1st group was 7[3.5; 7]. They developed on 3rd [2;4.5] day. Maximum level of ICP during plato waves was 47.5 [40;53] mmHg, its duration was 8.5 [7;27] minutes. In the group 1 Prx was significantly lower during first day, than in the group 2. Duration of ICP monitoring was longer in the group I due to presence of plato waves in these patients. CPP did not differ in groups, because CPP was strictly controlled. Patients of the group I had preserved autoregulation and less severe trauma (predominance of closed trauma and Marshall I, II type of brain damage). Plato waves did not predict bad outcomes.
authors: A V
authors: AV
authors: Oshorov
authors: I A
authors: IA
authors: Savin
authors: A S
authors: AS
authors: Goriachev
authors: K A
authors: KA
authors: Popugaev
authors: A A
authors: AA
authors: Polupan
authors: A A
authors: AA
authors: Sychev
authors: A G
authors: AG
authors: Gavrilov
authors: A D
authors: AD
authors: Kravchuk
authors: N E
authors: NE
authors: Zakharova
authors: G V
authors: GV
authors: Danilov
authors: A A
authors: AA
authors: Potapov
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000175:diagnosis* / Q000503:physiopathology*; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D007427:Intracranial Pressure / Q000502:physiology*; D008297:Male; D064926:Neurophysiological Monitoring / Q000295:instrumentation / Q000379:methods*; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies