title: Venlafaxine abuse in a patient with schizophrenia and prior history of substance dependence: a case report.
abstract: Venlafaxine is a serotonin/norepinephrine reuptake inhibitor that is believed to have no abuse potential. Currently, 2 published case reports argue against this notion. This article describes a third case of venlafaxine abuse and the first in the literature on a patient with schizophrenia. This article will also review the literature on venlafaxine abuse and propose a pharmacological explanation for its abuse potential. Healthcare practitioners need to be cautious when prescribing venlafaxine and other neuromodulatory medications.
authors: a Department of Psychiatry and Behavioral Sciences , Duke University , Durham , North Carolina , USA.
authors: Behrouz
authors: B
authors: Namdari
mesh_terms: D000328:Adult; D018687:Antidepressive Agents, Second-Generation / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D001008:Anxiety Disorders / Q000150:complications / Q000188:drug therapy; D003511:Cyclohexanols / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D058999:Drug-Seeking Behavior; D006801:Humans; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000150:complications* / Q000188:drug therapy; D012565:Schizophrenic Psychology; D019966:Substance-Related Disorders / Q000150:complications* / Q000523:psychology; D000069470:Venlafaxine Hydrochloride
chemical_list: D018687:Antidepressive Agents, Second-Generation; D003511:Cyclohexanols; D000069470:Venlafaxine Hydrochloride