title: Sella turcica atypical teratoid/rhabdoid tumor complicated with lung metastasis in an adult female.
abstract: Here we present the case of a 60-year-old woman with a rare sellar region atypical teratoid/rhabdoid tumor (AT/RT), complicated by lung metastasis and treated with neurosurgery, radiotherapy, and chemotherapy. The patient had recurrent headache associated with left cavernous sinus syndrome after a previous endonasal transsphenoidal resection for a presumptive pituitary macroadenoma. Pituitary magnetic resonance imaging showed a tumor regrowth in the original location with a haemorrhagic component involving the left cavernous sinus. A near complete transsphenoidal resection of the sellar mass was performed followed by 3 months of stereotactic radiotherapy. Because of a worsening of the general clinical conditions, respiratory failure, and asthenia, the patient underwent a contrast enhanced computer tomography of the whole body which showed the presence of lung metastasis. The histopathological diagnosis on samples from pituitary and lung tissues was AT/RT. The patient survived 30 months after diagnosis regardless chemotherapy. In the adult, the AT/RT should be considered as a possible rare, aggressive, and malignant neoplasm localized in the sella turcica.
authors: Unit of Endocrinology and Diabetes, Section of Reproductive Endocrinology University of Tor Vergata, San Giovanni Calibita Fatebenefratelli Hospital Tiber Island, Rome, Italy.
authors: Costanzo
authors: C
authors: Moretti
authors: Domenico
authors: D
authors: Lupoi
authors: Francesca
authors: F
authors: Spasaro
authors: Laura
authors: L
authors: Chioma
authors: Paola
authors: P
authors: Di Giacinto
authors: Martina
authors: M
authors: Colicchia
authors: Mario
authors: M
authors: Frajoli
authors: Renzo
authors: R
authors: Mocini
authors: Salvatore
authors: S
authors: Ulisse
authors: Manila
authors: M
authors: Antonelli
authors: Felice
authors: F
authors: Giangaspero
authors: Lucio
authors: L
authors: Gnessi
keywords: atypical teratoid/rhabdoid tumor (AT/RT); lung; metastasis; sella turcica