title: Palliative treatment of the advanced gastric cancer by means of surgery and HIPEC.
abstract: OBJECTIVE
  We demonstrate a case report of the patient who suffered from advanced gastric cancer and was treated by means of surgery and HIPEC.
  
  
  BACKGROUND
  Gastric cancer is a therapeutic challenge in the European countries due to late diagnosis, advanced stages of the disease in time of diagnosis and early recurrence in cases where a radical surgery is possible.
  
  
  METHODS
  The patient with an advanced gastric cancer (pT3N2M1 - peritoneal and ovarian metastases) was treated by means of radical surgery in combination with hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) and early postoperative intraperitoneal chemotherapy (EPIC). Surgical treatment was followed by a standard chemotherapy. Due to recurrence, there was the second look surgery one year later again with HIPEC procedure.
  
  
  RESULTS
  Patient survived 32 months after diagnosis and despite intraperitoneal recurrence she never developed clinically significant ascites and she never suffered from intestinal obstruction.
  
  
  CONCLUSIONS
  This case demonstrate a potential benefit of new oncosurgical approach -radical surgery + HIPEC + EPIC in the treatment of gastric cancers (Tab. 2, Fig. 6, Graph 4, Ref. 18). Text in PDF www.elis.sk.
authors: D
authors: D
authors: Hoskovec
authors: J
authors: J
authors: Varga
authors: F
authors: F
authors: Antos
authors: M
authors: M
authors: Kaspar
authors: P
authors: P
authors: Vitek
authors: K
authors: K
authors: Benkova
authors: P
authors: P
authors: Dytrych
authors: E
authors: E
authors: Konecna
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007274:Injections, Intraperitoneal; D007432:Intraoperative Period; D009367:Neoplasm Staging; D010166:Palliative Care / Q000379:methods*; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000628:therapy*
chemical_list: D000970:Antineoplastic Agents
keywords: gastric cancer, HIPEC, EPIC, radical surgery, peritoneal cytology.