title: Is there a relationship between pathologic myopia and dry eye syndrome?
abstract: OBJECTIVE
  The aim of this study was to investigate the relationship between pathologic myopia and the dry eye syndrome.
  
  
  METHODS
  Forty-five patients with a spherical equivalence (SE) greater than -6.0 diopters (D) and an axial length (AL) >26.5 mm were assigned to the pathological myopia group (group 1). Forty-four healthy individuals were selected from subjects with emmetropia whose SE values ranged from -1.0 to +1.0 D (group 2). Ocular surface disease index (OSDI) scores of all the patients were determined. All the participants underwent the following: Schirmer 1 test without anesthesia, corneal staining, tear break-up time (TBUT), Schirmer 1 test with anesthesia, and AL measurement.
  
  
  RESULTS
  The mean age of group 1 and group 2 patients was 40.2 ± 12.3 and 38.8 ± 9.3 years. The mean values of SE, keratometry, and AL were -9.6 ± 3.8 D, 43.9 ± 1.1 D, and 27.4 ± 0.6 mm in group 1 and -0.1 ± 0.5 D, 42.3 ± 1.4 D, and 23.0 ± 0.2 mm in group 2. The mean values of the Schirmer 1 test without and with anesthesia were 14.4 ± 6.1 and 9.5 ± 4.5 mm in group 1 and 16.7 ± 6.2 and 11.4 ± 6.0 mm in group 2. The mean TBUT in group 1 was 7.2 ± 3.4 seconds, whereas that in group 2 was 13.6 ± 3.7 seconds. There was a significant difference between the groups in SE, keratometry, AL, TBUT, and OSDI scores (P < 0.001).
  
  
  CONCLUSIONS
  Patients with pathologic myopia have lower TBUT scores and higher OSDI scores when compared with healthy individuals.
authors: Department of Ophthalmology, Mustafa Kemal University, Faculty of Medicine, Antakya, Hatay, Turkey.
authors: Nilufer
authors: N
authors: Ilhan
authors: Ozgur
authors: O
authors: Ilhan
authors: Esra
authors: E
authors: Ayhan Tuzcu
authors: Mutlu Cihan
authors: MC
authors: Daglioglu
authors: Mesut
authors: M
authors: Coskun
authors: Nihan
authors: N
authors: Parlakfikirer
authors: Ugurcan
authors: U
authors: Keskin
mesh_terms: D000293:Adolescent; D000328:Adult; D003315:Cornea / Q000503:physiopathology; D015352:Dry Eye Syndromes / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000175:diagnosis / Q000503:physiopathology*; D009994:Osmolar Concentration; D011795:Surveys and Questionnaires; D013666:Tears / Q000737:chemistry; D055815:Young Adult