title: Lack of polypoidal lesions in patients with myopic choroidal neovascularization as evaluated by indocyanine green angiography.
abstract: OBJECTIVE
  To investigate the prevalence of polypoidal choroidal vasculopathy (PCV) in patients with myopic choroidal neovascularization (CNV) using indocyanine green angiography (ICGA).
  
  
  METHODS
  Retrospective cross-sectional study.
  
  
  METHODS
  A total of 297 eyes (255 patients) who presented with treatment-naive myopic CNV between January 2005 and December 2011 at Yonsei University Medical Center in Seoul, South Korea, were reviewed. Fluorescein angiography (FA) images obtained from the patients were analyzed to detect CNV presence and classify disease type. ICGA images were reviewed to detect polypoidal lesions. The main outcome measure was the prevalence of polypoidal lesions in patients with myopic CNV.
  
  
  RESULTS
  All 297 eyes with myopic CNV were type 2 CNV, and mean age at diagnosis was 47.32 ± 14.69 years. The mean refractive error was -11.95 ± 5.88 diopters, and the mean axial length was 29.39 ± 2.02 mm in the affected eyes. Among the myopic CNV eyes, 141 eyes (118 patients) were older than 50 years of age (mean 60.48 ± 7.34 years). No eyes with myopic CNV showed polypoidal lesions on ICGA at initial presentation. After treatments for myopic CNV, 243 eyes (206 patients) completed at least 12 months of follow-up, and 86 eyes (35.4%) showed at least one recurrence of CNV during follow-up. The follow-up imaging studies, FA, and ICGA, showed no polypoidal lesions associated with recurred myopic CNV.
  
  
  CONCLUSIONS
  ICGA analysis demonstrated no polypoidal component in myopic eyes with CNV.
authors: Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, South Korea.
authors: Hae Min
authors: HM
authors: Kang
authors: Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, South Korea. Electronic address: hjkoh@yuhs.ac.
authors: Hyoung Jun
authors: HJ
authors: Koh
mesh_terms: D058452:Axial Length, Eye / Q000473:pathology; D020256:Choroidal Neovascularization / Q000145:classification / Q000175:diagnosis*; D004396:Coloring Agents; D003430:Cross-Sectional Studies; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000175:diagnosis*; D011127:Polyps / Q000175:diagnosis*; D012008:Recurrence; D012189:Retrospective Studies
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green