title: Transient acidosis during early reperfusion attenuates myocardium ischemia reperfusion injury via PI3k-Akt-eNOS signaling pathway.
abstract: In this paper, we concluded that transient acidosis reperfusion conferred cardioprotection against myocardial ischemia reperfusion injury in isolated rat hearts through activating PI3K-Akt-eNOS pathway.
authors: Department of Anesthesiology, Chongqing Zhoushan Hospital, Chongqing 404100, China ; Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 404100, China.
authors: Xin
authors: X
authors: Qiao
authors: Jinjin
authors: J
authors: Xu
authors: Qing-Jun
authors: QJ
authors: Yang
authors: Yun
authors: Y
authors: Du
authors: Shaoqing
authors: S
authors: Lei
authors: Zhi-Hong
authors: ZH
authors: Liu
authors: Xinwei
authors: X
authors: Liu
authors: Huimin
authors: H
authors: Liu
mesh_terms: D000138:Acidosis / Q000150:complications* / Q000201:enzymology* / Q000473:pathology / Q000503:physiopathology; D000818:Animals; D015237:Dinoprost / Q000031:analogs & derivatives; D004789:Enzyme Activation; D006334:Heart Function Tests; D057775:Ischemic Postconditioning; D028421:Isoprostanes / Q000378:metabolism; D008297:Male; D015428:Myocardial Reperfusion Injury / Q000150:complications* / Q000201:enzymology* / Q000473:pathology / Q000503:physiopathology; D009569:Nitric Oxide / Q000378:metabolism; D052250:Nitric Oxide Synthase Type III / Q000378:metabolism*; D010477:Perfusion; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D015398:Signal Transduction
chemical_list: D028421:Isoprostanes; C075750:8-epi-prostaglandin F2alpha; D009569:Nitric Oxide; D015237:Dinoprost; D052250:Nitric Oxide Synthase Type III; D019869:Phosphatidylinositol 3-Kinases; D051057:Proto-Oncogene Proteins c-akt