title: Functional outcomes following endoscopic laser cricopharyngeal myotomy with mucosal repair.
abstract: Endoscopic laser cricopharyngeal myotomy is an effective treatment for cricopharyngeal dysfunction, but concern remains over the risk of serious complications following the procedure. Some authors have therefore considered endoscopic laser cricopharyngeal myotomy with mucosal repair; however, outcome data for the procedure is scanty. This study aims to identify functional outcomes in a series of patients following endoscopic laser cricopharyngeal myotomy with mucosal repair. Endoscopic laser cricopharyngeal myotomy with mucosal repair was performed on 38 subjects in two centres over a period of 33 months. Pre- and post-operative outcomes were evaluated in 32 subjects using the Sydney Swallow Questionnaire and Reflux Symptom Index. An improvement in swallowing scores was seen in 30 subjects (94%, p < 0.001). The Reflux Symptom Index improved 28 subjects (88%, p < 0.001). Mean procedure time was 58 min. One subject (2.6%) developed mediastinitis following surgery, and four experienced (12.5%) a recurrence of dysphagic symptoms. Endoscopic laser cricopharyngeal myotomy with mucosal repair is an effective treatment for cricopharyngeal dysfunction. The complication rate observed in this study was comparable or lower than previously reported studies into endoscopic laser cricopharyngeal myotomy without mucosal repair. Larger studies may be required to determine the additional benefit of mucosal repair over endoscopic laser cricopharyngeal myotomy alone.
authors: ENT Department, John Radcliffe Hospital, Oxford, OX3 9DU, UK, otdale@doctors.net.uk.
authors: O T
authors: OT
authors: Dale
authors: S
authors: S
authors: Mackeith
authors: C A
authors: CA
authors: Burgess
authors: T J
authors: TJ
authors: Rourke
authors: S C
authors: SC
authors: Winter
authors: R J
authors: RJ
authors: Corbridge
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003680:Deglutition Disorders / Q000601:surgery*; D004724:Endoscopy; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000601:surgery; D053685:Laser Therapy / Q000379:methods*; D054020:Lasers, Gas / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000601:surgery*; D010609:Pharyngeal Muscles / Q000473:pathology / Q000601:surgery*; D011446:Prospective Studies; D016896:Treatment Outcome