title: In vivo analysis of antioxidant and prooxidant properties of retinol acetate.
abstract: Analysis of the effects of retinol acetate on LPO processes in vivo revealed antioxidant effects under normal conditions and during experimental free-radical pathology (toxic hepatosis-hepatitis). The concentration inversion of antioxidant effects of retinol acetate into prooxidant effects were observed only under normal conditions.
authors: Ryazan' State Medical University, Ministry of Health of the Russian Federation, Ryazan', Russia. psco@mail.ru.
authors: S K
authors: SK
authors: Pravkin
authors: E N
authors: EN
authors: Yakusheva
authors: D G
authors: DG
authors: Uzbekova
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage*; D004195:Disease Models, Animal; D004224:Diterpenes; D005609:Free Radicals / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000096:biosynthesis / Q000378:metabolism; D005982:Glutathione Transferase / Q000096:biosynthesis / Q000378:metabolism; D006505:Hepatitis / Q000188:drug therapy / Q000378:metabolism; D008054:Lipid Peroxides / Q000378:metabolism*; D008297:Male; D008315:Malondialdehyde / Q000032:analysis*; D051381:Rats; D017382:Reactive Oxygen Species / Q000378:metabolism; D000084562:Retinyl Esters; D014801:Vitamin A / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000097:blood
chemical_list: D000975:Antioxidants; D004224:Diterpenes; D005609:Free Radicals; D008054:Lipid Peroxides; D017382:Reactive Oxygen Species; D000084562:Retinyl Esters; D014801:Vitamin A; C009166:retinol acetate; D008315:Malondialdehyde; D005979:Glutathione Peroxidase; D005982:Glutathione Transferase