title: Circulation of classical swine influenza virus in Europe between the wars?
abstract: The complete genomes of two swine influenza viruses from England were sequenced. Phylogenetic analysis revealed classical swine H1N1 viruses, one of which, A/swine/London, is closely related to virus strains of the early 1930s. Both strains are also antigenically related to A/swine/Iowa/15/1930, the strain originally isolated by Richard Shope. The source of A/swine/London is unknown, but its relationship to early classical swine influenza viruses suggests that the emergence of these viruses in Europe has to be antedated by 15-20 years.
authors: Department of Virology and Antiviral Therapy, Jena University Hospital, Friedrich Schiller University, Hans-Knoell-Str. 2, 07745, Jena, Germany.
authors: Jeannette
authors: J
authors: Lange
authors: Marco
authors: M
authors: Groth
authors: Pumaree
authors: P
authors: Kanrai
authors: Stephan
authors: S
authors: Pleschka
authors: Christoph
authors: C
authors: Scholtissek
authors: Ralf
authors: R
authors: Dürrwald
authors: Matthias
authors: M
authors: Platzer
authors: Andreas
authors: A
authors: Sauerbrei
authors: Roland
authors: R
authors: Zell
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000235:genetics; D004739:England; D019143:Evolution, Molecular; D049673:History, 20th Century; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D007251:Influenza, Human / Q000453:epidemiology* / Q000266:history / Q000821:virology*; D009976:Orthomyxoviridae Infections / Q000453:epidemiology* / Q000266:history / Q000821:virology*; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology* / Q000266:history / Q000821:virology*
chemical_list: D000956:Antigens, Viral