title: A new dipeptide isolated from the bulb of garlic.
abstract: (R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid was isolated from the bulb of garlic, together with four known amino acids. Its structure was elucidated on the basis of 2D NMR and MS techniques. To the best of our knowledge, (R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid, which showed antibacterial activity against the Staphylococcus aureus antibiotic resistant strain, was the first example of dipeptide from garlic.
authors: a Department of Chemistry , Jinan University , Guangzhou , 510632 , P.R. China.
authors: Mei-Yun
authors: MY
authors: Zhou
authors: Zhao-Jun
authors: ZJ
authors: Wu
authors: Wen-Qing
authors: WQ
authors: Li
authors: Xing-Peng
authors: XP
authors: Hu
authors: Rian
authors: R
authors: Yan
authors: Shi-Yi
authors: SY
authors: Ou
authors: Hua
authors: H
authors: Zhou
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004151:Dipeptides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005737:Garlic / Q000737:chemistry*; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: C587304:(R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid; D000900:Anti-Bacterial Agents; D004151:Dipeptides; D004365:Drugs, Chinese Herbal