title: Fitness gains hamper efforts to tackle drug resistance.
abstract: It has long been assumed that resistance to antibiotics reduces the fitness of disease-causing bacteria, but experiments on Salmonella Typhi, the bacteria that causes Typhoid fever, are now challenging this view.
authors: Shanta Dutta is in the Bacteriology Division, National Institute of Cholera and Enteric Diseases, Kolkata, India shanta1232001@yahoo.co.in.
authors: Shanta
authors: S
authors: Dutta
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024841:Fluoroquinolones / Q000494:pharmacology*; D012485:Salmonella typhi / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones
keywords: Salmonella; antibiotic resistance; epistasis; fitness cost; fluoroquinolone; typhoid