title: The combination of thermal dysregulation and agenesis of corpus callosum: Shapiro's or/and reverse Shapiro's syndrome.
abstract: Shapiro syndrome is an extremely rare condition consisting the clinical triad of recurrent hypothermia, hyperhydrosis and agenesis of the corpus callosum. On the other hand, reverse Shapiro's sydrome is characterized periodic hyperthermia and agenesis of the corpus callosum. Here, we describe a 3.5-year-old girl with complete agenesis of corpus callosum presenting with recurrent fever and vomiting. She also had hypothermia attacks with accompanying diaphoresis. To the best of our knowledge, there is no described case with episodes of hyperthermia, hypothermia, and vomiting associated with agenesis of the corpus callosum. Recurrent vomiting may be a newly defined symptom associated with these syndromes.
authors: Department of Pediatrics, Dokuz Eylul University Medical Faculty, Division of Pediatric Neurology, İzmir, Turkey.
authors: Yasemin
authors: Y
authors: Topcu
authors: Erhan
authors: E
authors: Bayram
authors: Pakize
authors: P
authors: Karaoglu
authors: Uluc
authors: U
authors: Yis
authors: Semra Hiz
authors: SH
authors: Kurul
keywords: Agenesis of corpus callosum; Shapiro's syndrome; vomiting