title: Evaluating clinical course of BCG lymphadenitis and factors affect on it during a 5-year period in Kerman, Iran.
abstract: BACKGROUND
  One of the preventive methods of pulmonary tuberculosis is bacillus Calmette-Guérin (BCG) vaccination and one of the common complications of vaccine is lymphadenitis. We aimed to evaluate clinical course of BCG lymphadenitis in children of Kerman Province, Iran.
  
  
  METHODS
  314 children with BCG lymphadenitis were enrolled in study. Patients were followed up monthly regarding clinical improvement and complications.
  
  
  RESULTS
  BCG lymphadenitis was improved in many patients during follow up; during 6 months 23.7% of patients had spontaneous regression. Only the primary size of lymphadenitis had significant effect on clinical course of lymphadenitis and developing complication (p = 0.0540).
  
  
  CONCLUSIONS
  Many patients improved without any intervention. The primary size of lymphadenitis may affect clinical course of lymphadenitis and dispose person to abscess and fistula. To confirm this result and evaluate efficiency of preventive surgery instead of observation further study is recommended.
authors: Professor of Pediatrics, Department of Pediatrics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
authors: Mohammadhossein
authors: M
authors: Daei Parizi
authors: Amirhossein
authors: A
authors: Kardoust Parizi
authors: Sepide
authors: S
authors: Izadipour
mesh_terms: D000038:Abscess / Q000453:epidemiology / Q000382:microbiology; D001500:BCG Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007223:Infant; D007492:Iran / Q000453:epidemiology; D008199:Lymphadenitis / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D013492:Suppuration / Q000453:epidemiology / Q000382:microbiology; D014397:Tuberculosis, Pulmonary / Q000517:prevention & control*; D014611:Vaccination / Q000009:adverse effects
chemical_list: D001500:BCG Vaccine
keywords: BCG lymphadenitis; BCG vaccination; abscess; clinical course; fistula; spontaneous regression