title: Streptococcus pyogenes escapes from autophagy.
abstract: Autophagy is important for innate defense against intracellular bacteria, such as Group A Streptococcus (GAS). In this issue of Cell Host & Microbe, Barnett et al. (2013) demonstrate that the globally disseminated serotype M1T1 clone of GAS can evade autophagy via streptococcal cysteine protease SpeB-mediated degradation of ubiquitin-LC3 adaptor proteins.
authors: Section of Bacterial Pathogenesis, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan. Electronic address: ichiro-n.bac@tmd.ac.jp.
authors: Ichiro
authors: I
authors: Nakagawa
mesh_terms: D001343:Autophagy; D054884:Host-Pathogen Interactions; D006801:Humans; D057131:Immune Evasion; D013297:Streptococcus pyogenes / Q000276:immunology* / Q000502:physiology*