title: Chemistry, stability and bioavailability of resveratrol.
abstract: Resveratrol is a bioactive polyphenol found in many vegetables. It is well known for its multiple pharmacological activities, such as anti-inflammatory, antioxidant, antimicrobial, anticancer, neuroprotective and cardioprotective effects. In vitro evidence of resveratrol efficacy is widespread, however, many concerns regarding its effectiveness in vivo arise from its poor stability in vitro and bioavailability following oral ingestion. This review focuses on the in vitro stability, with special focus on the photochemical stability of resveratrol, and on the therapeutic perspectives of this molecule due to its low bioavailability.
authors: Antonio
authors: A
authors: Francioso
authors: Paola
authors: P
authors: Mastromarino
authors: Alessandra
authors: A
authors: Masci
authors: Maria
authors: M
authors: d'Erme
authors: Department of Biochemical Sciences, Sapienza University of Roma, p.le Aldo Moro, 5, 00185 Roma, Italy. antonio.francioso@uniroma1.it.
authors: Luciana
authors: L
authors: Mosca
mesh_terms: D001682:Biological Availability; D015394:Molecular Structure; D055668:Photochemical Processes; D000077185:Resveratrol; D013237:Stereoisomerism; D013267:Stilbenes / Q000737:chemistry* / Q000493:pharmacokinetics* / Q000627:therapeutic use
chemical_list: D013267:Stilbenes; D000077185:Resveratrol