title: Hemorrhagic radiation cystitis.
abstract: The optimal management of persistent hemorrhagic radiation cystitis is ill-defined. Various options are available and include oral agents (ie, sodium pentosan polysulfate), intravenous drugs (ie, WF10), topical agents (ie, formalin), hyperbaric oxygen, and endoscopic procedures (ie, electrical cautery, argon plasma coagulation, laser coagulation). In general, it is best to manage patients conservatively and intervene only when necessary with the option least likely to exacerbate the cystitis. More aggressive measures should be employed only when more conservative approaches fail. Bladder biopsies should be avoided, unless findings suggest a bladder tumor, because they may precipitate a complication.
authors: *Department of Radiation, University of Florida Proton Therapy Institute †Division of Urology, College of Medicine, University of Florida, Jacksonville, FL.
authors: William M
authors: WM
authors: Mendenhall
authors: Randal H
authors: RH
authors: Henderson
authors: Joseph A
authors: JA
authors: Costa
authors: Bradford S
authors: BS
authors: Hoppe
authors: Roi
authors: R
authors: Dagan
authors: Curtis M
authors: CM
authors: Bryant
authors: Romaine C
authors: RC
authors: Nichols
authors: Christopher R
authors: CR
authors: Williams
authors: Stephanie E
authors: SE
authors: Harris
authors: Nancy P
authors: NP
authors: Mendenhall
mesh_terms: D061605:Administration, Intravenous; D000283:Administration, Intravesical; D000284:Administration, Oral; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use; D002713:Chlorine / Q000008:administration & dosage; D003556:Cystitis / Q000209:etiology / Q000628:therapy*; D005557:Formaldehyde / Q000008:administration & dosage; D006417:Hematuria / Q000209:etiology / Q000628:therapy*; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage; D006931:Hyperbaric Oxygenation; D017075:Laser Coagulation; D010087:Oxides / Q000008:administration & dosage; D010426:Pentosan Sulfuric Polyester / Q000008:administration & dosage; D011832:Radiation Injuries / Q000628:therapy*; D011837:Radiation-Protective Agents / Q000008:administration & dosage; D011878:Radiotherapy / Q000009:adverse effects; D001743:Urinary Bladder / Q000528:radiation effects*
chemical_list: D000925:Anticoagulants; D010087:Oxides; D011837:Radiation-Protective Agents; D005557:Formaldehyde; D010426:Pentosan Sulfuric Polyester; D002713:Chlorine; D006820:Hyaluronic Acid; C041955:tetrachlorodecaoxide