title: [Survival analysis and risk factors for survival in idiopathic inflammatory myopathies: a retrospective cohort study].
abstract: OBJECTIVE
  To study predominant risk factors for survival in idiopathic inflammatory myopathies (JIM).
  
  
  METHODS
  The clinical data of 163 cases of IIM were reviewed, who received the diagnosis and treatments in West China Hospital from January 1997 to December 2010. Kaplan-Meier survival curve was used for the survival analysis of these patients with IIM. Univariate and multivariate analysis of risk factors for survival in the patients with IIM were carried out by Log-rank test, univariate Cox regression analysis and Cox regression model respectively.
  
  
  RESULTS
  There were 21 death occured among 163 patients with IIM, and the estimated 3, 5, 10-year survival rate was 93%, 89%, 80% respectively. The mortality of the patients with dermatomyositis (DM) or amyophathic dermatomyositis(ADM) increased significantly when compared with polymyositis (PM, P=0. 033, P= 0. 06). The mortality of IIM patients complicated with tumor or cadiovascular involvement was much higher than that of those patients without any complications (P<0. 001, P=0. 015). Tumor and cadiovascular involvement were two independent risk factors for the survival of IIM individuals.
  
  
  CONCLUSIONS
  DM and ADM have much unfavorable prognosis than PM. Tumor and cadiovascular involvement are two major risk factors for the survival of IIM patients.
authors: Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China.
authors: Geng
authors: G
authors: Yin
authors: Yan
authors: Y
authors: Liang
authors: Rong
authors: R
authors: Deng
authors: Ying
authors: Y
authors: Wang
authors: Qi-Bing
authors: QB
authors: Xie
authors: Chuan
authors: C
authors: Zuo
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000150:complications; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009220:Myositis / Q000401:mortality*; D009369:Neoplasms / Q000150:complications; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis