title: The use of nanocomposite coatings with various physicochemical properties in tissue engineering.
abstract: We studied the effect of nanocomposite coatings with various physicochemical properties on the structural and functional properties (adhesion potential, phenotype, gene expression) of mesenchymal stem cells. Of all tested nanocoatings (Al2O3, ZrO2, Ta2O5), oxide coating Al2O3 enriched in vitro monolayer bone marrow cell culture with cells carrying mesenchymal stem cells phenotype markers and stimulated expression of ido gene, which can confer new therapeutic potencies to these cells and extend their application in clinical practice.
authors: Institute for Problems of Cryobiology and Cryomedicine, National Academy of Sciences of Ukraine, Khar'kov; National Science Center Kharkov Institute of Physics and Technology, National Academy of Science, Ukraine. cryopato@rambler.ru.
authors: A N
authors: AN
authors: Gol'tsev
authors: I V
authors: IV
authors: Rassokha
authors: T G
authors: TG
authors: Dubrava
authors: L V
authors: LV
authors: Ostankova
authors: M V
authors: MV
authors: Ostankov
authors: E A
authors: EA
authors: Gordienko
authors: V I
authors: VI
authors: Safonov
authors: A V
authors: AV
authors: Zykova
mesh_terms: D000537:Aluminum Oxide / Q000494:pharmacology; D000818:Animals; D000943:Antigens, Differentiation / Q000096:biosynthesis; D001854:Bone Marrow Cells / Q000187:drug effects; D002448:Cell Adhesion / Q000187:drug effects*; D002478:Cells, Cultured; D020099:Coated Materials, Biocompatible / Q000737:chemistry / Q000494:pharmacology*; D015870:Gene Expression / Q000187:drug effects; D050503:Indoleamine-Pyrrole 2,3,-Dioxygenase / Q000096:biosynthesis*; D008422:Materials Testing; D059630:Mesenchymal Stem Cells / Q000187:drug effects*; D051379:Mice; D008808:Mice, Inbred CBA; D053761:Nanocomposites / Q000737:chemistry*; D010087:Oxides / Q000494:pharmacology; D013499:Surface Properties; D013635:Tantalum / Q000494:pharmacology; D023822:Tissue Engineering / Q000379:methods*; D015040:Zirconium / Q000494:pharmacology
chemical_list: D000943:Antigens, Differentiation; D020099:Coated Materials, Biocompatible; C583637:IDO1 protein, mouse; D050503:Indoleamine-Pyrrole 2,3,-Dioxygenase; D010087:Oxides; D013635:Tantalum; D015040:Zirconium; D000537:Aluminum Oxide; C078151:tantalum oxide; C028541:zirconium oxide