title: [Sero-epidemiological analysis for entervirus 71 infection of adults in Beijing].
abstract: OBJECTIVE
  To evaluate the enterovirus 71 (EV 71) protective antibody level of health adults people in Beijing.
  
  
  METHODS
  Serum samples and information of participants were collected from hospitals in Beijing. EV71 IgG was tested by enzyme-linked immunoadsordent assay (ELISA). EV 71 neutralization antibody was evaluated by micro-cytopathic effect neutralization test (MCPENT).
  
  
  RESULTS
  486 participants were enrolled. Age range was 19-62 years old. The average EV 71 IgG positive rate was 40. 3% , there are no significant difference between the EV 71 IgG positive rate of male and female. The rate of EV 71 neutralization antibody which title high than 1:256 is 13.3%. The rate of EV 71 IgG and the titile of EV 71 neutralization antibody are decreasing by the age.
  
  
  CONCLUSIONS
  40% of health adults of Beijing area have EV71 protective antibody. But the title higher than 1:256 is only 13.3%. EV 71 protective antibody decreases significantly with the age.
authors: Beijiing Hospital, Beijing 100730, China. dongich@cmde.org.cn
authors: Jing-Jing
authors: JJ
authors: Wang
authors: Wei
authors: W
authors: Wu
authors: Hui-Jie
authors: HJ
authors: Pan
mesh_terms: D000328:Adult; D000367:Age Factors; D057134:Antibodies, Neutralizing / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood*; D002681:China; D029821:Enterovirus A, Human / Q000276:immunology / Q000302:isolation & purification*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged
chemical_list: D057134:Antibodies, Neutralizing; D000914:Antibodies, Viral; D007074:Immunoglobulin G