title: TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours.
authors: Northern Institute for Cancer Research, Newcastle University, Royal Victoria Infirmary, Newcastle upon Tyne, UK.
authors: Janet C
authors: JC
authors: Lindsey
authors: Ed C
authors: EC
authors: Schwalbe
authors: Sandeep
authors: S
authors: Potluri
authors: Simon
authors: S
authors: Bailey
authors: Daniel
authors: D
authors: Williamson
authors: Steven C
authors: SC
authors: Clifford
mesh_terms: D000293:Adolescent; D002528:Cerebellar Neoplasms / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D019175:DNA Methylation / Q000235:genetics*; D004273:DNA, Neoplasm / Q000235:genetics; D057890:Epigenomics; D015972:Gene Expression Regulation, Neoplastic / Q000235:genetics; D006801:Humans; D008527:Medulloblastoma / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D009154:Mutation / Q000235:genetics*; D011401:Promoter Regions, Genetic / Q000235:genetics*; D019098:Telomerase / Q000235:genetics* / Q000378:metabolism*
chemical_list: D004273:DNA, Neoplasm; C509186:TERT protein, human; D019098:Telomerase