title: Boron-trihalide-promoted regioselective ring-opening reactions of gem-difluorocyclopropyl ketones.
abstract: Boron trihalide-promoted ring-opening reactions of gem-difluorocyclopropyl ketones to give the corresponding β-trifluoromethyl ketones and β-halodifluoromethyl ketones were described. It was found that boron trihalides act as both Lewis acids and nucleophiles and the proximal bond prefers to cleave in this transformation.
authors: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China. jchxiao@sioc.ac.cn.
authors: Tang-Po
authors: TP
authors: Yang
authors: Qiang
authors: Q
authors: Li
authors: Jin-Hong
authors: JH
authors: Lin
authors: Ji-Chang
authors: JC
authors: Xiao
mesh_terms: D001895:Boron / Q000737:chemistry*; D002384:Catalysis; D006219:Halogens / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D006219:Halogens; D007659:Ketones; D001895:Boron