title: Shockingly: the loss of Lyn leads to leakiness.
abstract: In this issue of Blood, Han et al demonstrate that endotoxin-induced mortality in a murine model of acute lung injury (ALI) was associated with increased vascular permeability attributable to loss of the Src family kinase (SFK) Lyn.
authors: NORTHWESTERN FEINBERG SCHOOL OF MEDICINE;
authors: Seth J
authors: SJ
authors: Corey
authors: Regina M
authors: RM
authors: Day
mesh_terms: D022005:Adherens Junctions / Q000201:enzymology*; D000818:Animals; D002199:Capillary Permeability / Q000502:physiology*; D042783:Endothelial Cells / Q000201:enzymology*; D004730:Endothelium, Vascular / Q000201:enzymology*; D006801:Humans; D019061:src-Family Kinases / Q000378:metabolism*
chemical_list: C060902:lyn protein-tyrosine kinase; D019061:src-Family Kinases