title: Hydrogen-bonding in aminocatalysis: from proline and beyond.
abstract: This Concept article summarizes recent progress in the field of hydrogen-bonding aminocatalysis using proline-derived systems. The aminocatalysts available in the literature are categorized by the incorporated hydrogen-bonding scaffold and its mode of recognition. Both mono- and double-hydrogen-bonding motifs are discussed and examples of their application in asymmetric synthesis are given.
authors: Department of Chemistry, Institute of Organic Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Lodz (Poland).
authors: Lukasz
authors: L
authors: Albrecht
authors: Hao
authors: H
authors: Jiang
authors: Karl Anker
authors: KA
authors: Jørgensen
mesh_terms: D002384:Catalysis; D006860:Hydrogen Bonding; D011392:Proline / Q000031:analogs & derivatives* / Q000737:chemistry*; D011759:Pyrrolidines / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D011759:Pyrrolidines; D011392:Proline
keywords: aminocatalysis; asymmetric catalysis; bifunctional catalysis; hydrogen bonds; proline; stereoselective synthesis