title: Two cases of acute respiratory distress syndrome with high values of Chlamydophila pneumoniae-specific antibodies.
abstract: We herein report two cases of acute respiratory distress syndrome (ARDS) with high values of Chlamydophila pneumoniae-specific antibodies. In the first case (a 65-year-old man), high levels of anti-C. pneumoniae antibodies (IgG and IgA) were detected on admission, and the anti-C. pneumoniae IgA level rose by Day 30. The patient was successfully treated with quinolone and steroids. In the second case (an 85-year-old man), abnormally high levels of anti-C. pneumoniae IgM were detected on admission. The patient did not recover, despite receiving treatment with several antibiotics and anti-inflammatory agents. Neither of the patients displayed other pathogen-specific antigens or antibodies. Chlamydophila pneumonia is usually mild, although it can cause severe interstitial pneumonia and ARDS in reinfected patients and the elderly.
authors: Department of Respiratory Medicine, Osaki Citizen Hospital, Japan.
authors: Ryotaro
authors: R
authors: Igusa
authors: Atsushi
authors: A
authors: Nakamura
authors: Sachiko
authors: S
authors: Kawana
authors: Taizou
authors: T
authors: Shibahara
authors: Sodai
authors: S
authors: Narumi
authors: Takuya
authors: T
authors: Oikawa
authors: Kazunori
authors: K
authors: Yoshida
authors: Takafumi
authors: T
authors: Kobayashi
authors: Kozo
authors: K
authors: Ota
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000096:biosynthesis* / Q000097:blood; D023521:Chlamydophila Infections / Q000175:diagnosis / Q000276:immunology*; D016993:Chlamydophila pneumoniae / Q000276:immunology*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000276:immunology; D008297:Male; D012128:Respiratory Distress Syndrome / Q000175:diagnosis / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial