title: [The role of genetic factors in the development of chronic dust bronchitis in workers of coal mining enterprises of Kuzbass].
abstract: The distribution of genotypes of HP, GC, EsD, AsP and polymorphisms GSTT1 (GST-theta1) and GSTM1 (GST-micro1) and NOS3 (polymorphism VNTR4) in miners with chronic dust bronchitis, and in those without this occupational disease has been studied The carriers of genotypes of genotypes EsD 1-2, AsP bb were shown to be more prone to develop chronic dust bronchitis. Endogenous factors of resistance to the disease are the genotypes GC 1-1, EsD 1-1, AsP bc.
authors: N I
authors: NI
authors: Gafarov
authors: V V
authors: VV
authors: Zakharenkov
authors: N I
authors: NI
authors: Panev
authors: A N
authors: AN
authors: Kucher
authors: M B
authors: MB
authors: Freĭdin
authors: A A
authors: AA
authors: Rudko
mesh_terms: D000328:Adult; D000395:Air Pollutants, Occupational / Q000633:toxicity*; D029481:Bronchitis, Chronic / Q000139:chemically induced / Q000235:genetics*; D016022:Case-Control Studies; D003032:Coal Mining; D004391:Dust; D059647:Gene-Environment Interaction; D020022:Genetic Predisposition to Disease; D005838:Genotype; D005982:Glutathione Transferase / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D052250:Nitric Oxide Synthase Type III / Q000235:genetics; D009784:Occupational Diseases / Q000139:chemically induced / Q000235:genetics*; D011110:Polymorphism, Genetic; D012800:Siberia
chemical_list: D000395:Air Pollutants, Occupational; D004391:Dust; D005982:Glutathione Transferase; D052250:Nitric Oxide Synthase Type III; C496314:NOS3 protein, human; C413545:glutathione S-transferase T1