title: Clinico-epidemiological profile of seven adults with spotted fever from a tertiary care hospital in South India.
abstract: Spotted fever (SF), a tick-borne rickettsial infection, is being increasingly reported from mainly northern Indian states. A lack of awareness and confirmatory laboratory tests underestimate the incidence of this infection which, in India, is predominantly seen during the rainy season. Many patients diagnosed with viral exanthematous illnesses may be suffering from SF, which is treatable if detected early. There is very little data on SF in adults in southern India. We present seven patients with SF treated between January 2007 and January 2008 in a tertiary care hospital in South India. All presented during the rainy season, with rash (100%) and generalized oedema (71%) being the most common features. There was one death due to type I respiratory failure. Renal failure, shock, aseptic meningitis and hepatitis were other significant abnormalities detected in these patients. Clinicians need to be aware of SF and suspect it in appropriate patients.
authors: Associate Professor of Geriatrics, Department of Geriatrics and Internal Medicine Unit 3, Christian Medical College, Vellore, India.
authors: Kango Gopal
authors: KG
authors: Gopinath
authors: Anugrah
authors: A
authors: Chrispal
authors: Harikishan
authors: H
authors: Boorugu
authors: Sara
authors: S
authors: Chandy
authors: John Jude
authors: JJ
authors: Prakash
authors: Asha Mary
authors: AM
authors: Abraham
authors: O C
authors: OC
authors: Abraham
authors: Kurien
authors: K
authors: Thomas
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000097:blood; D001907:Boutonneuse Fever / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D004318:Doxycycline / Q000627:therapeutic use; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005335:Fever of Unknown Origin / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D007075:Immunoglobulin M; D015994:Incidence; D007194:India / Q000453:epidemiology; D008297:Male; D011446:Prospective Studies; D020114:Rickettsia conorii / Q000276:immunology / Q000302:isolation & purification; D063128:Tertiary Health Care; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D007075:Immunoglobulin M; D004318:Doxycycline
keywords: Spotted fever; southern Indian adults