title: [Cutaneous leishmaniasis. Diagnosis and therapy in northern Afghanistan].
abstract: BACKGROUND
  The German S1 guidelines from 2009 contain a variety of recommendations for the treatment of cutaneous leishmaniasis.
  
  
  METHODS
  We report the results of our diagnostic procedures and treatment of 32 international patients in autumn 2010 in northern Afghanistan.
  
  
  RESULTS
  Giemsa stain confirmed the clinical diagnosis within 24 hours. Eleven simple lesions and one larger ulcer responded well to cryotherapy and intralesional sodium stibogluconate. More complex lesions in 19 patients responded well to oral miltefosine. One patient refused outpatient therapy.
  
  
  CONCLUSIONS
  Cryotherapy and intralesional antimony compounds showed good results in early lesions of cutaneous leishmaniasis in northern Afghanistan. Outpatient treatment of complex lesions with miltefosine was successful in all cases.
authors: Fachsanitätszentrum Leipzig , Kornblumenweg 4, 04158, Leipzig, Deutschland, Rolf.Dieterle@t-online.de.
authors: R
authors: R
authors: Dieterle
authors: H
authors: H
authors: Pillekamp
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000346:Afghanistan; D000967:Antimony Sodium Gluconate / Q000008:administration & dosage*; D000981:Antiprotozoal Agents / Q000008:administration & dosage; D003131:Combined Modality Therapy; D017679:Cryotherapy / Q000379:methods*; D003879:Dermatologic Agents / Q000008:administration & dosage; D006801:Humans; D038622:Internationality; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D008889:Military Personnel; D010767:Phosphorylcholine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000981:Antiprotozoal Agents; D003879:Dermatologic Agents; D010767:Phosphorylcholine; C039128:miltefosine; D000967:Antimony Sodium Gluconate