title: Transcatheter aortic valve replacement: current status and future directions.
abstract: Transcatheter aortic valve replacement (TAVR) is a revolutionary therapy for patients with aortic stenosis. Large registries and randomized controlled trials have demonstrated that TAVR is safe and effective in patients considered inoperable because of severe comorbidities and those who are high-risk surgical candidates. As TAVR evolves for lower-risk patients, attention will need to focus on reducing the rates of vascular injury, stroke, and paravalvular regurgitation. In this review, we discuss the status of TAVR in clinical practice, including patient selection, preoperative evaluation, techniques, and complications.
authors: Department of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.
authors: Chintan S
authors: CS
authors: Desai
authors: Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, Ohio.
authors: Eric E
authors: EE
authors: Roselli
authors: Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, Ohio.
authors: Lars G
authors: LG
authors: Svensson
authors: Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois. Electronic address: r-bonow@northwestern.edu.
authors: Robert O
authors: RO
authors: Bonow
mesh_terms: D001024:Aortic Valve Stenosis / Q000175:diagnosis / Q000628:therapy*; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000639:trends*; D015897:Comorbidity; D003952:Diagnostic Imaging; D005544:Forecasting; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000639:trends*; D006801:Humans; D018579:Patient Selection; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome
keywords: aortic stenosis; aortic valve replacement; transcatheter aortic valve replacement