title: Axial biometry of the entire eye using ultra-long scan depth optical coherence tomography.
abstract: OBJECTIVE
  To assess the repeatability of axial biometry of the entire eye using ultra-long scan depth optical coherence tomography (OCT) and to investigate the agreement with IOLMaster measurements (Carl Zeiss Meditec).
  
  
  METHODS
  Prospective, observational case series.
  
  
  METHODS
  There were 37 adult subjects enrolled in group 1 and 12 adult subjects enrolled in group 2. Using ultra-long scan depth OCT, the left eyes of these groups were measured in 2 separate sessions. The images were processed by a manual method and custom-developed automatic software. A model eye was imaged for verification. The subjects in group 2 were imaged using ultra-long scan depth OCT and using the IOLMaster for axial length measurement comparison.
  
  
  RESULTS
  All measured parameters of the model eye matched the geometric parameters. In group 1, there were no significant differences in all measured parameters using automatic and manual segmentation methods (P > .05, paired t test). The percentage of coefficient of repeatability of segments ranged from 0.3% to 3.9%. The corresponding interclass correlation coefficients ranged from 0.946 to 0.999. The correlation between the results using automatic and manual segmentation methods appeared to be strong (R(2) = 0.999; P < .05). In group 2, the axial length of the eye measured by the IOLMaster matched the results obtained by ultra-long scan depth OCT with the automatic method (R1(2) = 0.987; P < .05) and the manual method (R2(2) = 0.988; P < .05).
  
  
  CONCLUSIONS
  Automatic axial biometry using ultra-long scan depth OCT successfully measured each segment of the entire eye with good repeatability. With further development of automatic segmentation, ultra-long scan depth OCT seems to be a promising tool in the axial biometry of the entire eye.
authors: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida; Department of Ophthalmology, Hangzhou First People's Hospital, Hangzhou, Zhejiang, China.
authors: Jianguang
authors: J
authors: Zhong
authors: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
authors: Yilei
authors: Y
authors: Shao
authors: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
authors: Aizhu
authors: A
authors: Tao
authors: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
authors: Hong
authors: H
authors: Jiang
authors: Department of Biomedical Engineering, University of Miami, Miami, Florida.
authors: Che
authors: C
authors: Liu
authors: Department of Ophthalmology, Hangzhou First People's Hospital, Hangzhou, Zhejiang, China.
authors: Huicheng
authors: H
authors: Zhang
authors: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida. Electronic address: jwang3@med.miami.edu.
authors: Jianhua
authors: J
authors: Wang
mesh_terms: D000328:Adult; D000368:Aged; D058452:Axial Length, Eye / Q000033:anatomy & histology*; D001699:Biometry; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D055095:Optics and Photonics; D011446:Prospective Studies; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence / Q000379:methods*; D055815:Young Adult