title: A small molecule two-photon fluorescent probe for intracellular sodium ions.
abstract: We report a small-molecule two-photon fluorescent probe (ANa2) for Na(+) that shows a strong TPEF enhancement in response to Na(+) and can be easily loaded into live cells and can real time monitor the fluctuation of [Na]i in live cells and living tissue at more than 100 μm depth.
authors: Division of Energy Systems Research, Ajou University, Suwon, 443-749, Korea. kimhm@ajou.ac.kr.
authors: Avik Ranjan
authors: AR
authors: Sarkar
authors: Cheol Ho
authors: CH
authors: Heo
authors: Mi Yeon
authors: MY
authors: Park
authors: Hyo Won
authors: HW
authors: Lee
authors: Hwan Myung
authors: HM
authors: Kim
mesh_terms: D000818:Animals; D001253:Astrocytes; D005456:Fluorescent Dyes / Q000494:pharmacology*; D018698:Glutamic Acid / Q000494:pharmacology; D006367:HeLa Cells; D006573:Heterocyclic Compounds, 1-Ring / Q000494:pharmacology*; D006624:Hippocampus / Q000378:metabolism; D006632:Histamine / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D036641:Microscopy, Fluorescence, Multiphoton; D011392:Proline / Q000031:analogs & derivatives* / Q000494:pharmacology; D051381:Rats; D012964:Sodium / Q000378:metabolism*
chemical_list: D005456:Fluorescent Dyes; D006573:Heterocyclic Compounds, 1-Ring; D018698:Glutamic Acid; D006632:Histamine; D011392:Proline; D012964:Sodium