title: Probing the mechanisms underlying the mitigation of cognitive aging with anodal transcranial direct current stimulation.
abstract: Meinzer et al. (J Neurosci 33: 12470-12478, 2013) have recently reported that anodal transcranial direct current stimulation (atDCS) mitigates age-related cognitive changes. Simultaneous measurement of BOLD signal during atDCS also showed "youth-like" processing in an elderly population. Although the effects are very promising, the underlying mechanisms of atDCS are still not clear. In this article, we provide a critical review of the results, emphasizing the article's significance and providing additional insight that will help elucidate the results and atDCS mechanisms.
authors: Department of Neuroscience, Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey.
authors: Kohitij
authors: K
authors: Kar
authors: Jessica
authors: J
authors: Wright
mesh_terms: D001921:Brain / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D046690:Deep Brain Stimulation / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D009415:Nerve Net / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*
keywords: BOLD; anodal transcranial direct current stimulation; brain-derived neurotrophic factor; cognitive aging; regional cerebral blood flow