title: Dimercuration of calix[4]arenes: novel substitution pattern in calixarene chemistry.
abstract: A mercuration reaction of tetrapropoxycalix[4]arene immobilized in the cone conformation gave a mixture of two dimercurated products (meta,meta and meta,para) in approximately a 1:1 ratio. Both regioisomers represent inherently chiral compounds, which makes them very attractive for design of novel receptors. As demonstrated by Pd-catalyzed arylation, the different reactivity of HgCl functions in the meta,para-disubstituted isomer opens the door for regioselective introductions of two different functional groups to achieve a substitution pattern so far unknown in calixarene chemistry.
authors: Department of Organic Chemistry, ‡Laboratory of NMR Spectroscopy, and §Department of Solid State Chemistry. Prague Institute of Chemical Technology (PICT) , Technicka 6, 166 28 Prague 6, Czech Republic.
authors: Karolína
authors: K
authors: Flídrová
authors: Stanislav
authors: S
authors: Böhm
authors: Hana
authors: H
authors: Dvořáková
authors: Václav
authors: V
authors: Eigner
authors: Pavel
authors: P
authors: Lhoták