title: Gastric adenocarcinoma of the fundic gland type (chief cell predominant type).
abstract: Gastric adenocarcinoma of the fundic gland (chief cell predominant type, GA-FG-CCP) was recently proposed as a new, rare variant of gastric adenocarcinoma. The aim of the current study was to evaluate the endoscopic features of GA-FG-CCP. A total of 10 GA-FG-CCPs were included and evaluated retrospectively. The endoscopic and clinicopathological features of the lesions were analyzed to provide information of diagnostic value. The GA-FG-CCPs were classified into two categories: submucosal tumor shape (60 %) and flat or depressed type (40 %). Endoscopically, the most common features were submucosal tumor shape (60 %), whitish color (70 %), dilated vessels with branching architecture (50 %), and background mucosa without atrophic change (90 %). GA-FG-CCP has distinct endoscopic characteristics, especially in terms of shape, color, vessels, and background mucosa and may be classified into two categories macroscopically. To diagnose GA-FG-CCP correctly by pathological examination of biopsy specimens, these endoscopic features should be taken into consideration.
authors: Department of Gastroenterology, Juntendo University, School of Medicine, Tokyo, Japan.
authors: Hiroya
authors: H
authors: Ueyama
authors: Department of Gastroenterology, Juntendo University, School of Medicine, Tokyo, Japan.
authors: Kenshi
authors: K
authors: Matsumoto
authors: Department of Gastroenterology, Juntendo University, School of Medicine, Tokyo, Japan.
authors: Akihito
authors: A
authors: Nagahara
authors: Department of Human Pathology, Juntendo University, School of Medicine, Tokyo, Japan.
authors: Takuo
authors: T
authors: Hayashi
authors: Department of Human Pathology, Juntendo University, School of Medicine, Tokyo, Japan.
authors: Takashi
authors: T
authors: Yao
authors: Department of Gastroenterology, Juntendo University, School of Medicine, Tokyo, Japan.
authors: Sumio
authors: S
authors: Watanabe
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D016145:Endoscopy, Digestive System; D005260:Female; D005748:Gastric Fundus / Q000473:pathology; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology*