title: Use of β-blockade and levosimendan for separation from extracorporeal life support in an infant with postoperative diastolic dysfunction.
abstract: Diastolic dysfunction is common in infants and neonates with left ventricular (LV) outflow tract obstruction and may lead to low-cardiac output in the postoperative period. We present a management strategy for severe postrepair diastolic dysfunction in an infant with critical congenital aortic stenosis and LV hypertrophy, employing β-blockade and levosimendan.
authors: Department of Pediatric Cardiac Surgery, Mater Children's Hospital, Brisbane, Australia.
authors: Ragini
authors: R
authors: Pandey
authors: Karthik
authors: K
authors: Ramakrishnan
authors: Alex
authors: A
authors: Gooi
authors: Tom
authors: T
authors: Karl
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D001024:Aortic Valve Stenosis / Q000151:congenital / Q000601:surgery*; D002316:Cardiotonic Agents / Q000627:therapeutic use; D003971:Diastole; D004359:Drug Therapy, Combination; D005112:Extracorporeal Circulation / Q000379:methods*; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006801:Humans; D006835:Hydrazones / Q000627:therapeutic use*; D007231:Infant, Newborn; D008297:Male; D011183:Postoperative Complications; D011724:Pyridazines / Q000627:therapeutic use*; D000077464:Simendan; D018754:Ventricular Dysfunction / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D014694:Ventricular Outflow Obstruction / Q000601:surgery
chemical_list: D000319:Adrenergic beta-Antagonists; D002316:Cardiotonic Agents; D006835:Hydrazones; D011724:Pyridazines; D000077464:Simendan
keywords: Ross-Konno operation; cardiac function; extracorporeal membrane oxygenation; pharmacology