title: Solitary rectal ulcer syndrome in children: a report of six cases.
abstract: Solitary rectal ulcer syndrome (SRUS) is a rare, benign disorder in children that usually presents with rectal bleeding, constipation, mucous discharge, prolonged straining, tenesmus, lower abdominal pain, and localized pain in the perineal area. The underlying etiology is not well understood, but it is secondary to ischemic changes and trauma in the rectum associated with paradoxical contraction of the pelvic floor and the external anal sphincter muscles; rectal prolapse has also been implicated in the pathogenesis. This syndrome is diagnosed based on clinical symptoms and endoscopic and histological findings, but SRUS often goes unrecognized or is easily confused with other diseases such as inflammatory bowel disease, amoebiasis, malignancy, and other causes of rectal bleeding such as a juvenile polyps. SRUS should be suspected in patients experiencing rectal discharge of blood and mucus in addition to previous disorders of evacuation. We herein report six pediatric cases with SRUS.
authors: Division of Pediatric Gastroenterology, Sisli Etfal Training and Research Hospital, Istanbul, Turkey.
authors: Nafiye
authors: N
authors: Urgancı
authors: Derya
authors: D
authors: Kalyoncu
authors: Kamile Gulcin
authors: KG
authors: Eken
mesh_terms: D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D002648:Child; D003113:Colonoscopy; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis*; D006801:Humans; D008297:Male; D019804:Mesalamine / Q000627:therapeutic use; D012002:Rectal Diseases / Q000175:diagnosis* / Q000188:drug therapy; D013256:Steroids / Q000627:therapeutic use; D013392:Sucralfate / Q000627:therapeutic use; D013577:Syndrome; D014456:Ulcer / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000897:Anti-Ulcer Agents; D013256:Steroids; D019804:Mesalamine; D013392:Sucralfate
keywords: Child; Rectal bleeding; Solitary rectal ulcer