title: Does fibromyalgia influence symptom bother from pelvic organ prolapse?
abstract: OBJECTIVE
  Determine if women with fibromyalgia report increased bother from pelvic organ prolapse compared with women without fibromyalgia.
  
  
  METHODS
  We performed a cross-sectional study of women with symptomatic prolapse on consultation with a private urogynecology practice within a 46-month period. After matching for age, women with a diagnosis of fibromyalgia were compared with a reference group of women without fibromyalgia. Demographic, POPQ examination, medical history, and pelvic floor symptom data (PFDI, PFIQ, and PISQ-12) were collected. Our primary outcome was to compare the mean Pelvic Floor Distress Inventory (PFDI) scores of women with and without fibromyalgia.
  
  
  RESULTS
  The prevalence of fibromyalgia in women evaluated for initial urogynecology consultation during the study period was 114 out of 1,113 (7%). Women with fibromyalgia reported significantly higher symptom bother scores related to pelvic organ prolapse, defecatory dysfunction, urinary symptoms, and sexual function: PFDI (p = 0.005), PFIQ (p=0.010), and PISQ (p=0.018). Women with fibromyalgia were found to have a higher BMI (p=0.008) and were more likely to report a history of sexual abuse, OR 3.1 (95 % CI 1.3, 7.9), and have levator myalgia on examination, OR 3.8 (95% CI 1.5, 9.1). In a linear regression analysis, levator myalgia was found to be the significant factor associated with pelvic floor symptom bother.
  
  
  CONCLUSIONS
  In women with symptomatic prolapse, fibromyalgia is associated with an increased risk of levator myalgia and 50% more symptom bother from pelvic floor disorders.
authors: Oregon Health & Science University, Mail code: L466, 3181 S.W. Sam Jackson Park Road, Portland, OR, 97239-3098, USA, kerrie.adams@med.navy.mil.
authors: Kerrie
authors: K
authors: Adams
authors: Blake
authors: B
authors: Osmundsen
authors: W Thomas
authors: WT
authors: Gregory
mesh_terms: D003430:Cross-Sectional Studies; D005260:Female; D005356:Fibromyalgia / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000150:complications* / Q000175:diagnosis*; D012189:Retrospective Studies; D012720:Severity of Illness Index