title: Bullous disorders as a manifestation of immune reconstitution inflammatory syndrome: A series of three cases.
abstract: Bullous disorders such as pemphigus vulgaris, bullous pemphigoid after the initiation of highly active antiretroviral therapy in certain human immunodeficiency virus reactive individuals have been described in this case series as a manifestation of an immune reconstitution inflammatory syndrome. This phenomenon should be suspected in individuals who present with bullous lesions within 3-8 weeks after initiation of therapy despite of improved immunological response. Strong clinical suspicion, through clinical examination, appropriate laboratory investigation such as CD4 T-cell count, histopathological examinations with H and E stain, direct immunofluorescence test are required for diagnosis.
authors: Department of Pathology, School of Tropical Medicine, Kolkata, West Bengal, India.
authors: Rama
authors: R
authors: Das
authors: Somenath
authors: S
authors: Sarkar
authors: Mrinal
authors: M
authors: Besra
keywords: Bullous pemphigoid; immune reconstitution; pemphigus vulgaris