title: [The stiff-person syndrome: a brief review and report of two cases].
abstract: The stiff-person syndrome is a rare and progressive neuromuscular disease which appears to have an immunpathological basis. It is characterised by painful muscle spasms and stiffness in the proximal muscles, especially those attached to the axial skeleton. The precise pathophysiology is still unknown, but several antibodies have been shown to be present in patients and these antibodies are directed against proteins which play a role in the inhibitor synapse linked to gamma-amino-butyrate. In the first part of the article the authors present two cases. In the second part they present a comprehensive review of our current knowledge about this rare disease. Orv.Hetil., 154(50), 1984-1990.
authors: Batthyány Kázmér Szakkórház Kisbér Iskola u. 11. 2870.
authors: Zsuzsanna
authors: Z
authors: Kemény
authors: Patrícia
authors: P
authors: Pálfi
authors: Judit
authors: J
authors: Demeter
authors: Gyula
authors: G
authors: Poór
authors: Emese
authors: E
authors: Kiss
authors: Péter
authors: P
authors: Bálint
mesh_terms: D006801:Humans; D016750:Stiff-Person Syndrome
keywords: GABARAP; GAD; amphiphysin; amphyphysin; gephyrin; stiff-person syndrome; stiff-person-szindróma