title: Biopsychosocial factors associated with pain in veterans with the hepatitis C virus.
abstract: Little research has examined etiological factors associated with pain in patients with the hepatitis C virus (HCV). The purpose of this study was to evaluate the relationship between biopsychosocial factors and pain among patients with HCV. Patients with HCV and pain (n = 119) completed self-report measures of pain, mental health functioning, pain-specific psychosocial variables (pain catastrophizing, self-efficacy for managing pain, social support), prescription opioid use, and demographic characteristics. In multivariate models, biopsychosocial factors accounted for 37% of the variance in pain severity and 56% of the variance in pain interference. In adjusted models, factors associated with pain severity include pain catastrophizing and social support, whereas variables associated with pain interference were age, pain intensity, prescription opioid use, and chronic pain self-efficacy (all p values <0.05). The results provide empirical support for incorporating the biopsychosocial model in evaluating and treating chronic pain in patients with HCV.
authors: Mental Health and Clinical Neurosciences Division, Portland VA Medical Center (R&D99), 3710 SW US Veterans Hospital Road, Portland, OR, 97239, USA, benjamin.morasco@va.gov.
authors: Benjamin J
authors: BJ
authors: Morasco
authors: Travis I
authors: TI
authors: Lovejoy
authors: Dennis C
authors: DC
authors: Turk
authors: Aysha
authors: A
authors: Crain
authors: Peter
authors: P
authors: Hauser
authors: Steven K
authors: SK
authors: Dobscha
mesh_terms: D000328:Adult; D000367:Age Factors; D000701:Analgesics, Opioid / Q000627:therapeutic use; D005260:Female; D006526:Hepatitis C / Q000150:complications / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy / Q000209:etiology / Q000523:psychology*; D010147:Pain Measurement; D011584:Psychology; D020377:Self Efficacy; D012944:Social Support; D014728:Veterans / Q000523:psychology* / Q000706:statistics & numerical data
chemical_list: D000701:Analgesics, Opioid