title: Synthesis of three OSW-1 analogs with maltose side chains bearing different protection groups.
abstract: In order to simplify the synthesis of OSW-1's disaccharide side chain and explore the structure-activity relationship of OSW-1, three 16α-O-maltose OSW-1 analogs carrying three maltose side chains bearing different protections were designed and synthesized.
authors: a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences , Peking , 100050 , China.
authors: Yu-Yao
authors: YY
authors: Guan
authors: Chao
authors: C
authors: Song
authors: Ping-Sheng
authors: PS
authors: Lei
mesh_terms: D002783:Cholestenones / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D015195:Drug Design; D004354:Drug Screening Assays, Antitumor; D006367:HeLa Cells; D006801:Humans; D007624:KB Cells; D015394:Molecular Structure; D012503:Saponins / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D002783:Cholestenones; D012503:Saponins; C106408:OSW 1