title: Clinical efficacy of a herbal dentifrice on dentinal hypersensitivity: a randomized controlled clinical trial.
abstract: BACKGROUND
  Dentinal hypersensitivity is a common problem and there is a growing interest in herbal based formulations for the treatment of oral diseases. This study was conducted to assess the efficacy of a commercially available novel herbal dentifrice in reduction of dentinal hypersensitivity.
  
  
  METHODS
  A total of 73 subjects (38 males and 35 females; aged 25-60 years) were randomly divided into two groups: Group 1 - a placebo dentifrice (The Himalaya Drug Company Research and Development, Makali, Bangalore) and Group 2 - (test group), a commercially available herbal dentifrice (Hi Ora K, The Himalaya Drug Company Research and Development, Makali, Bangalore). Sensitivity scores for controlled air stimulus and cold water were recorded at baseline, 6 weeks and 12 weeks.
  
  
  RESULTS
  The test group was found to be significantly better compared to the placebo group at the end of 6 and 12 weeks in reduction of dentinal hypersensitivity.
  
  
  CONCLUSIONS
  The novel herbal dentifrice can be recommended for treatment of dentinal hypersensitivity.
authors: Department of Periodontics, Government Dental College and Research Institute, Bangalore, India.
authors: M
authors: M
authors: Kumari
authors: S B
authors: SB
authors: Naik
authors: N S
authors: NS
authors: Rao
authors: S S
authors: SS
authors: Martande
authors: A R
authors: AR
authors: Pradeep
mesh_terms: D000328:Adult; D000388:Air; D000475:Alkenes / Q000737:chemistry; D002935:Cinnamomum zeylanicum / Q000737:chemistry; D003802:Dentifrices / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D009566:Nitrates / Q000627:therapeutic use*; D008517:Phytotherapy / Q000379:methods*; D010880:Piperidines / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D017680:Potassium Compounds / Q000627:therapeutic use*; D018724:Spinacia oleracea / Q000737:chemistry*; D027842:Syzygium / Q000737:chemistry; D014867:Water; D015034:Zinc Oxide / Q000627:therapeutic use
chemical_list: D000475:Alkenes; D003802:Dentifrices; D009566:Nitrates; D010880:Piperidines; D010936:Plant Extracts; D017680:Potassium Compounds; C540456:trikatu; C520904:triphala; D014867:Water; C023844:potassium nitrate; D015034:Zinc Oxide
keywords: Clinical trial; Spinacia oleracea; dentifrice; dentine desensitizing agents; potassium nitrate