title: Cyclodextrin polymer/Fe3O4 nanocomposites as solid phase extraction material coupled with UV-vis spectrometry for the analysis of rutin.
abstract: In this paper, carboxymethyl-hydroxypropyl-β-cyclodextrin polymer modified magnetic particles Fe3O4 (CM-HP-β-CDCP-MNPs) were prepared and applied to magnetic solid phase extraction of rutin combined with UV-visible spectrometry detection. The synthesized magnetic particles were characterized by element analysis, Fourier transform infrared spectra, thermal gravimetric analysis, and transmission electron microscopy. Several variables affecting the extraction and desorption of rutin such as pH, the amount of adsorbent, the type and volume of eluent, extraction and desorption time, and temperature were investigated. The maximum adsorption capacity was 67.0 mg g(-1) for rutin with the equilibrium time of 30 min at room temperature, and the adsorbent could be reused for 10 times. A calibration curve was linear in the range of 0.05-8.00 μg mL(-1) with a relative standard deviation of 2.9% (n=5, c=4.0 μg mL(-1)). The limit of detection was 7.0 ng mL(-1). The interaction mechanism between the adsorbent and rutin was also studied. Feasibility of this method was validated by the analysis of rutin tablets and lotus plumule.
authors: College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China; Yangzhou Polytechnic Institute, Yangzhou 225002, China.
authors: Aiqin
authors: A
authors: Gong
authors: College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
authors: Wenhui
authors: W
authors: Ping
authors: College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
authors: Jue
authors: J
authors: Wang
authors: College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China. Electronic address: xszhu@yzu.edu.cn.
authors: Xiashi
authors: X
authors: Zhu
mesh_terms: D000327:Adsorption; D002482:Cellulose / Q000737:chemistry*; D003505:Cyclodextrins / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D058185:Magnetite Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D059027:Recycling; D012431:Rutin / Q000032:analysis* / Q000737:chemistry; D052616:Solid Phase Extraction / Q000379:methods*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013607:Tablets; D013696:Temperature; D013818:Thermogravimetry
chemical_list: D003505:Cyclodextrins; D005290:Ferric Compounds; D058185:Magnetite Nanoparticles; D013607:Tablets; C041953:cyclodextrin polymer; C000499:ferric oxide; D012431:Rutin; D002482:Cellulose
keywords: Magnetic nanocomposites; Rutin; Solid-phase extraction; UV-visible spectrophotometry