title: Child neurology: differential diagnosis of a low CSF glucose in children and young adults.
abstract: Analysis of CSF is daily routine in patients with acute neurologic disorders like CNS infections. In those patients, the finding of a low CSF glucose may influence further diagnostic workup and therapeutic choices. The interpretation of a low CSF glucose in patients with a chronic neurologic disorder, however, is a less common practice. We present a practical overview on the differential diagnosis of a low CSF glucose and stress the importance of recognizing a low CSF glucose as the diagnostic marker for GLUT1 deficiency syndrome, a treatable neurometabolic disorder.
authors: From the Department of Neurology (W.G.L., B.G.E., M.M.V.) and Department of Pediatric Neurology (M.A.W.), Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, the Netherlands; Department of Pediatrics (C.J.d.W.), Genetics (E.J.K.), and Laboratory Medicine (M.M.V., R.A.W.), Radboud University Medical Centre, Nijmegen, the Netherlands; and Department of Pediatrics and Pediatric Neurology (J.K.), Children's Hospital, Aschaffenburg, Germany.
authors: Wilhelmina G
authors: WG
authors: Leen
authors: Cornelis J
authors: CJ
authors: de Wit
authors: Ron A
authors: RA
authors: Wevers
authors: Baziel G
authors: BG
authors: van Engelen
authors: Erik-Jan
authors: EJ
authors: Kamsteeg
authors: Joerg
authors: J
authors: Klepper
authors: Marcel M
authors: MM
authors: Verbeek
authors: Michèl A
authors: MA
authors: Willemsen
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000134:cerebrospinal fluid; D002648:Child; D003937:Diagnosis, Differential; D005947:Glucose / Q000134:cerebrospinal fluid*; D006801:Humans; D008297:Male; D009422:Nervous System Diseases / Q000134:cerebrospinal fluid* / Q000175:diagnosis*; D055815:Young Adult
chemical_list: D015415:Biomarkers; D005947:Glucose