title: Single-blind randomized clinical trial to evaluate clinical and radiological outcomes after one year of immediate versus delayed implant placement supporting full-arch prostheses.
abstract: OBJECTIVE
  To evaluate and compare peri-implant health, marginal bone loss and success of immediate and delayed implant placement for rehabilitation with full-arch fixed prostheses.
  
  
  METHODS
  The present study was a prospective, randomized, single-blind, clinical preliminary trial. Patients were randomized into two treatment groups. In Group A implants were placed immediately post-extraction and in Group B six months after extraction. The following control time-points were established: one week, six months and twelve months after loading. Measurements were taken of peri-implant crevicular fluid volume, plaque index, gingival retraction, keratinized mucosa, probing depth, modified gingival index and presence of mucositis. Implant success rates were evaluated for the two groups. The study sample included fifteen patients (nine women and six men) with a mean average age of 63.7 years. One hundred and forty-four implants were placed: 76 placed in healed sites and 68 placed immediately.
  
  
  RESULTS
  At the moment of prosthetic loading, keratinized mucosa width and probing depth were higher in immediate implants than delayed implants, with statistically significant differences. However, after six and twelve months, differences between groups had disappeared. Bone loss was 0.54 ± 0.39 mm for immediate implants and 0.66 ± 0.25 mm for delayed implants (p=0.201). No implants failed in either group.
  
  
  CONCLUSIONS
  The present study with a short follow-up and a small sample yielded no statistically significant differences in implant success and peri-implant marginal bone loss between immediate and delayed implants with fixed full-arch prostheses. Peri-implant health showed no statistically significant differences for any of the studied parameters (crevicular fluid volume, plaque index, gingival retraction, keratinized mucosa, probing depth, modified gingival index and presence of mucositis) at the twelve-month follow-up.
authors: Universidad de Valencia, Clínica Odontológica, Unidad de Cirugía Bucal, Calle Gascó Oliag 1, 46021 Valencia, Spain, miguel.penarrocha@uv.es.
authors: Hilario
authors: H
authors: Pellicer-Chover
authors: David
authors: D
authors: Peñarrocha-Oltra
authors: Leticia
authors: L
authors: Bagán
authors: Antonio-J
authors: AJ
authors: Fichy-Fernandez
authors: Luigi
authors: L
authors: Canullo
authors: Miguel
authors: M
authors: Peñarrocha-Diago
mesh_terms: D003757:Dental Implantation / Q000379:methods*; D019094:Dental Prosthesis, Implant-Supported; D005260:Female; D006801:Humans; D057893:Immediate Dental Implant Loading; D007568:Jaw / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011474:Prosthesis Design; D011859:Radiography; D016037:Single-Blind Method; D013997:Time Factors; D016896:Treatment Outcome