title: The clinical-epidemological study of drugs used to treat arterial hypertension and associated comorbidities.
abstract: OBJECTIVE
  The objective of this study was to investigate the drug treatment of AHT according to the grade and associated comorbidities: diabetes, chronic kidney disease, angina pectoris.
  
  
  METHODS
  This study is a retrospective one, comprising a total of 1064 patients admitted to the Clinical Rehabilitation Hospital lasi, Cardiovascular Rehabilitation Clinic between 01.01.2011 - 31.12.2012. We noted the epidemiological data on the distribution of AHT according to area of origin, sex, age, and the pharmacological treatment according to the AHT grade and related diseases.
  
  
  RESULTS
  The results obtained were statistically analyzed by comparing drugs used together, their number depending on the AHT grade and associated comorbidities in order to achieve target values of blood pressure and reduce cardiovascular risk. The strategies used to control blood pressure were the gradual increase of the dose of drug or its replacement, switching from monotherapy to combination therapy, starting treatment with two drugs or administration of fixed combinations.
  
  
  CONCLUSIONS
  The most used antihypertensive drugs were the angiotensin receptor blockers, ACE inhibitors, calcium blockers, diuretics and beta blockers. Some patients have even received triple therapy.
authors: Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa" - Iasi.
authors: Maria-Magdalena
authors: MM
authors: Leon
authors: F
authors: F
authors: Mitu
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000188:drug therapy / Q000453:epidemiology; D057911:Angiotensin Receptor Antagonists / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D015897:Comorbidity; D048909:Diabetes Complications / Q000188:drug therapy / Q000453:epidemiology; D004232:Diuretics / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D051436:Renal Insufficiency, Chronic / Q000188:drug therapy / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D004232:Diuretics