title: En route to multicatalysis: kinetic resolution of trans-cycloalkane-1,2-diols via oxidative esterification.
abstract: We demonstrate the application of a multicatalyst to the oxidation of a broad variety of aldehydes and subsequent enantioselective esterification of the incipient acids with (±)-trans-cycloalkane-1,2-diols. This reaction operates well with a multicatalyst bearing two independent catalytic moieties that provide monoprotected 1,2-diols in one pot.
authors: Institute of Organic Chemistry, Justus-Liebig University, Heinrich-Buff-Ring 58, 35392 Giessen, Germany. prs@uni-giessen.de.
authors: Christine
authors: C
authors: Hofmann
authors: Sören M M
authors: SM
authors: Schuler
authors: Raffael C
authors: RC
authors: Wende
authors: Peter R
authors: PR
authors: Schreiner
mesh_terms: D000438:Alcohols / Q000737:chemistry; D000447:Aldehydes / Q000737:chemistry; D000473:Alkanes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D004952:Esters / Q000737:chemistry*; D007700:Kinetics; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D000447:Aldehydes; D000473:Alkanes; D004952:Esters