title: Overcoming immunosuppression as a new immunotherapeutic approach against pancreatic cancer.
abstract: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of malignancy. Via a broad stimulation of the immune system, PDAC activates both antitumor immune responses and immunosuppressive mechanisms. We propose that new immunotherapeutic strategies for the management of PDAC should be designed to specifically neutralize the immunosuppressive tumor microenvironment.
authors: Department of General Surgery; University of Heidelberg; Heidelberg, Germany.
authors: Alexandr V
authors: AV
authors: Bazhin
authors: Jagadeesh
authors: J
authors: Bayry
authors: Viktor
authors: V
authors: Umansky
authors: Jens
authors: J
authors: Werner
authors: Svetlana
authors: S
authors: Karakhanova
keywords: immunosuppression; immunotherapy; pancreatic cancer; regulatory T cells