title: Rigidity loss of protein macromolecule induced by force--effective field theory.
abstract: In the framework of the effective field theory for the order parameter, which characterizes the degree of deviating the protein globule structure from its native state, the phase transition of the protein macromolecule from the elastic state into the plastic one under its mechanical stretching is considered. Elastic properties of a protein are studied as a function of the applied force, temperature, and the mean coordination number of the protein "network."
authors: Kurchatov Institute, 123182, Moscow, Russia; Department of General Physics, Moscow Institute of Physics and Technology (State University), 9, Institutsky lane, Dolgoprudny, 141707, Russia.
authors: E Z
authors: EZ
authors: Meilikhov
authors: R M
authors: RM
authors: Farzetdinova
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D004548:Elasticity; D008958:Models, Molecular; D011485:Protein Binding; D011487:Protein Conformation; D055550:Protein Stability; D011506:Proteins / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D011506:Proteins
keywords: mean-field theory; percolation nature of protein rigidity; sharp drop of protein elasticity; stretching a protein