title: TfOH-catalyzed formal [3 + 2] cycloaddition of cyclopropane 1,1-diesters with nitriles.
abstract: A triflic acid-catalyzed formal [3 + 2] cycloaddition of cyclopropane 1,1-diesters with nitriles was developed. This reaction was expeditious, and the scope of the substituents in both cyclopropanes and nitriles was broad. This supplies an efficient and practical method for the synthesis of 1-pyrrolines.
authors: State Key Laboratory and Institute of Elemento-Organic Chemistry, Synergetic Innovation Center of Chemical Science and Engineering (Tianjin), Nankai University , 94 Weijin Road, Tianjin 300071, P. R. China.
authors: Bo
authors: B
authors: Cui
authors: Jun
authors: J
authors: Ren
authors: Zhongwen
authors: Z
authors: Wang
mesh_terms: D002384:Catalysis; D003500:Cyclization; D003521:Cyclopropanes / Q000737:chemistry*; D004952:Esters; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D003521:Cyclopropanes; D004952:Esters; D008698:Mesylates; D009570:Nitriles; D011758:Pyrroles; C013231:pyrroline; C012077:trifluoromethanesulfonic acid