title: Noncanonical Wnt comes of age in hematopoietic stem cells.
abstract: Understanding molecular mechanisms of aging is crucial in efforts to reverse it. In a recent issue of Nature, Florian et al. (2013) report that increasing levels of noncanonical Wnt signaling accompany hematopoietic stem cell (HSC) aging, which can be modulated to functionally rejuvenate HSCs.
authors: Laboratory of Ageing Biology and Stem Cells, European Research Institute for the Biology of Ageing, University Medical Centre Groningen, University of Groningen, Antonius Deusinglaan 1, Building 3226, 9713AV Groningen, The Netherlands.
authors: Evgenia
authors: E
authors: Verovskaya
authors: Gerald
authors: G
authors: de Haan
mesh_terms: D000818:Animals; D016922:Cellular Senescence; D005260:Female; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D008297:Male; D060449:Wnt Signaling Pathway