title: [A case of prostate carcinosarcoma successfully treated with combined modality therapy].
abstract: A 58-year-old man was referred to our hospital with dysuria and elevation of prostate specific antigen (38.0 ng/ml). Prostate surface was smooth and elastic hard on digital rectal examination. Transrectal ultrasound (TRUS) indicated irregular boundary and low echoic area of the prostate. Prostate biopsy specimen included the components of adenocarcinoma (Gleason score 9) and sarcoma. The tumor had extended to the rectum and metastasized to bilateral obturator lymph nodes and right ischial bone (cT4N1M1b). We started hormone therapy for the adenocarcinoma component followed by total pelvic exenteration with colostomy and ileal conduit diversion for the sarcoma component. In addition, pelvic cavity and the bone metastasis were irradiated. The patient was free of recurrence at four and a half years after surgery.
authors: The Department of Urology, Kyoto University Hospital.
authors: Takashi
authors: T
authors: Matsuoka
authors: Yoshio
authors: Y
authors: Sugino
authors: Takashi
authors: T
authors: Kobayashi
authors: Naoki
authors: N
authors: Terada
authors: Toshinari
authors: T
authors: Yamasaki
authors: Yoshiyuki
authors: Y
authors: Matsui
authors: Masaaki
authors: M
authors: Imamura
authors: Kazutoshi
authors: K
authors: Okubo
authors: Tomomi
authors: T
authors: Kamba
authors: Koji
authors: K
authors: Yoshimura
authors: Osamu
authors: O
authors: Ogawa
mesh_terms: D002296:Carcinosarcoma / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000628:therapy*; D016896:Treatment Outcome