title: [Infertility in women: latest developments].
abstract: BACKGROUND
  The incidence of female infertility has not changed since the early 1990s. Based on new data from basic research on infertility, novel options in the diagnostics and treatment of infertility have emerged, besides in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).
  
  
  OBJECTIVE
  This review summarizes the current knowledge on female infertility and on modern concepts in diagnostics and treatment.
  
  
  METHODS
  A literature research on the causes of infertility and on treatment options was performed, including demographic factors, infectiology, anatomy, endocrinology and metabolism, endometriosis, lifestyle and environmental factors, and psychological factors.
  
  
  RESULTS
  Chlamydial infection is still the major cause of tubal infertility. Improvement of the patient's fertility by correction of endocrine and metabolic disorders, in particular thyroid dysfunction and glucose metabolism, as well as fertility surgery are of main interest.
  
  
  CONCLUSIONS
  Besides assisted reproductive techniques, concepts to optimize individual fertility have gained increasing importance.
authors: Abteilung für Gynäkologische Endokrinologie und Fertilitätsstörungen, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Deutschland, thomas_strowitzki@med.uni-heidelberg.de.
authors: T
authors: T
authors: Strowitzki
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002694:Chlamydiaceae Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D010062:Ovulation Induction / Q000379:methods*; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*
chemical_list: D000900:Anti-Bacterial Agents