title: Selective synthesis of multisubstituted olefins utilizing gem- and vic-diborylated vinylsilanes prepared by silylborylation of an alkynylboronate and diborylation of alkynylsilanes.
abstract: The synthesis of a series of gem- and vic-diborylated vinylsilanes was accomplished via highly selective transition-metal-catalyzed syn-dimetalation to the alkynylmetal species. This protocol served as a general synthetic method toward regio- and stereodefined multisubstituted olefins. The key steps are the diastereoselective Suzuki-Miyaura cross-coupling reactions of gem- and vic-diborylated vinylsilanes, in which the two boron groups showed discrete reactivities to afford diverse precursors of multisubstituted olefins.
authors: Division of Earth, Life, and Molecular Sciences, Graduate School of Natural Science and Technology, Okayama University , 3-1-1 Tsushimanaka, Kita-ku, Okayama 700-8530, Japan.
authors: Jiao
authors: J
authors: Jiao
authors: Keita
authors: K
authors: Hyodo
authors: Hao
authors: H
authors: Hu
authors: Kiyohiko
authors: K
authors: Nakajima
authors: Yasushi
authors: Y
authors: Nishihara