title: Effects of glucocorticoid antagonist on protein carbonylation in rat liver after daily 1-hour immobilizations.
abstract: Daily (for 3 days) 1-hour immobilizations were followed by an increase in protein oxidative modification and leukocyte infiltration in the liver, and a decrease in monoamine oxidase B activity. Receptor antagonist of glucocorticoids RU38486 limited the stress-induced increase in protein carbonylation and decrease in monoamine oxidase B activity in the organ and enhanced leukocyte infiltration of the liver.
authors: Chelyabinsk State Medical Academy, Ministry of Health of the Russian Federation, Russia. vadimed@yandex.ru.
authors: V E
authors: VE
authors: Tseilikman
authors: V E
authors: VE
authors: Ryabinin
authors: O B
authors: OB
authors: Tseilikman
authors: A I
authors: AI
authors: Sinitskii
authors: R V
authors: RV
authors: Deev
mesh_terms: D000818:Animals; D021461:Animals, Outbred Strains; D005260:Female; D005938:Glucocorticoids / Q000037:antagonists & inhibitors; D006727:Hormone Antagonists / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000276:immunology / Q000378:metabolism*; D008297:Male; D015735:Mifepristone / Q000494:pharmacology*; D008995:Monoamine Oxidase / Q000378:metabolism; D050050:Protein Carbonylation / Q000187:drug effects*; D051381:Rats; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000276:immunology / Q000378:metabolism*
chemical_list: D005938:Glucocorticoids; D006727:Hormone Antagonists; D015735:Mifepristone; D008995:Monoamine Oxidase