title: Mini-sternotomy approach for aortic valve replacement in a patient with osteogenesis imperfecta.
abstract: Osteogenesis imperfecta (OI) is a heritable disorder of the connective tissue. Cardiovascular involvement is rare, related mainly to aortic valve regurgitation. Open-heart surgery in these patients is associated with increased morbidity and mortality rates as a result of tissue friability and bone brittleness as well as platelet dysfunction. We present a patient with OI who underwent successful aortic valve replacement with a mini-sternotomy approach.
authors: Department of Cardiothoracic Surgery, University Hospital of Wales, Heath Park, Cardiff, United Kingdom.
authors: Georgios
authors: G
authors: Dimitrakakis
authors: Jitendrakumar
authors: J
authors: Rathod
authors: Ulrich Otto
authors: UO
authors: von Oppell
authors: Agamemnon
authors: A
authors: Pericleous
authors: Stephen
authors: S
authors: Hutchison
mesh_terms: D000328:Adult; D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D018618:Echocardiography, Doppler, Color; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D019060:Minimally Invasive Surgical Procedures; D010013:Osteogenesis Imperfecta / Q000150:complications* / Q000175:diagnosis; D013902:Radiography, Thoracic; D056346:Sternotomy / Q000379:methods*; D016896:Treatment Outcome