title: Association between respiratory mechanics and autonomic function in morbid obesity.
abstract: This study aimed to investigate the association between respiratory mechanics and autonomic modulation in morbidly obese patients. We evaluated 10 morbidly obese subjects (BMI=52.9±11.2kg/m(2)), aged 23-58 years. Assessment of respiratory mechanics was done by the forced oscillation technique (FOT), and cardiovascular autonomic function was recorded by heart rate variability analysis (HRV). The Pearson correlation coefficient was used to test the associations between respiratory mechanics and HRV variables. There were associations between the standard deviation of all RR intervals (SDNN) and airway resistance (Rm) (r=-0.82; p=0.004), SDNN and respiratory system resistance (R0) (r=-0.79; p=0.006), root mean square of successive differences between adjacent normal RR intervals (rMSSD) and respiratory system resistance (R5) (r=-0.643; p=0.0451), rMSSD and R0 (r=-0.64; p=0.047), and rMSSD and Rm (r=-0.658; p=0.039). We concluded that the airway and respiratory system resistances are negatively associated with parasympathetic activity in patients with morbid obesity.
authors: Programa de Cirurgia Bariátrica, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil; Centro Universitário Plínio Leite, Rio de Janeiro, Brasil.
authors: M
authors: M
authors: Sant' Anna
authors: Programa de Cirurgia Bariátrica, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
authors: R F
authors: RF
authors: Carvalhal
authors: Programa de Cirurgia Bariátrica, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
authors: J R I
authors: JR
authors: Carneiro
authors: Departamento de Fisioterapia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
authors: M S
authors: MS
authors: Lapa
authors: Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
authors: W A
authors: WA
authors: Zin
authors: Programa de Pós-graduação em Ciências Médicas, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brasil.
authors: J R
authors: JR
authors: Lugon
authors: Departamento de Fisioterapia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil; Programa de Mestrado em Ciências da Reabilitação, Centro Universitário Augusto Motta, Rio de Janeiro, Brasil. Electronic address: fguimaraes_pg@yahoo.com.br.
authors: F S
authors: FS
authors: Guimarães
mesh_terms: D000328:Adult; D001341:Autonomic Nervous System / Q000503:physiopathology; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000503:physiopathology*; D015656:Respiratory Mechanics; D055815:Young Adult
keywords: Forced oscillation technique; Função pulmonar; Heart rate variability; Morbid obesity; Obesidade mórbida; Pulmonary function; Técnica de oscilação forçada; Variabilidade da frequência cardíaca