title: Insulin-like growth factor-I and fast growth-hormone levels in mild and moderately malnourished children.
abstract: Insulin-like growth factor-I (IGF-I)and fasting growth hormone levels were measured in a group of 255 children (163 males and 92 females. age ranged 6-17 years) of varying pubertal development and body mass index (BMI); well-nourished (BMI> 18). mildly-malnourished (BMI = 15-18) and moderately-malnourished (BMI<15). In well-nourished children IGF-I levels increased significantly (P = 0.02) with pubertal development. where girls at Tanner 5 had significantly higher (p = 0.03) IGF-I levels than the boys. Whilst there was no change in fasting GH levels with nutritional status, IGF-I levels of prepubertal boys and girls decreased significantly with BMI (P<0.001 and P = 0.01 respectively). Hence. measurement of IGF-I levels is a sensitive biochemical index in the assessment of mild and moderate form of malnutrition in prepubertal children.
authors: Universiti Kebangsaan Malaysia, Jin. Raja Muda Abd. Aziz, 50300 Kuala Lumpur, Malaysia.
authors: W M
authors: WM
authors: Wan Nazaimoona
authors: A
authors: A
authors: Osman
authors: M L
authors: ML
authors: Ng
authors: T T
authors: TT
authors: Tan
authors: L L
authors: LL
authors: Wu
authors: O
authors: O
authors: Sakinah
authors: A K
authors: AK
authors: Khalid