title: [Self-medication to treat pain in attacks of familial Mediterranean fever: aiming to find a new approach to pain management].
abstract: BACKGROUND
  Familial Mediterranean fever (FMF) is an autoinflammatory disease characterized by bouts of fever and serositis. Morbidity caused by bouts as well as self-medication were assessed among patients of Turkish ancestry living in Germany (D) or Turkey (T) in order to evaluate current analgetic concepts from a patient's perspective.
  
  
  METHODS
  D and T were asked about the 3 months preceding the interview.
  
  
  RESULTS
  A total of 40 D and 40 T were included; 35/40 D and 40/40 T were on colchicine. In the last 3 months, 61.3 % had ≥ 1 bout and suffered from peritonitis (87.8 %), fever (61.2 %), myalgia (45 %), pleuritis (42.8 %), arthralgia (36.7 %), and cephalgia (32.6 %). Of the patients, 65.3 % were bedridden during bouts, 61.2 % sought the attention of a physician, 53.1 % were unable to work or attend school, and 38.8 % were hospitalized. The following drugs were taken: NSAIDs (45.6 %), NSAIDs and paracetamol (42.6 %), and combinations of NSAIDs with other analgesics. NSAIDs (58.6 %) and paracetamol (20.7 %) were considered the most potent substances.
  
  
  CONCLUSIONS
  FMF inflicts substantial morbidity. Patients most commonly rely on NSAIDs and paracetamol to relieve symptoms of FMF bouts.
authors: Medizinische Klinik I, St. Josef-Hospital Bochum, Ruhr-Universität Bochum, Gudrunstr. 56, 44791, Bochum, Deutschland, arnd.giese@rub.de.
authors: A
authors: A
authors: Giese
authors: A
authors: A
authors: Ornek
authors: M
authors: M
authors: Kurucay
authors: L
authors: L
authors: Kilic
authors: S N
authors: SN
authors: Şendur
authors: A
authors: A
authors: Münker
authors: C
authors: C
authors: Puchstein
authors: E
authors: E
authors: Lainka
authors: H
authors: H
authors: Wittkowski
authors: B F
authors: BF
authors: Henning
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage*; D000701:Analgesics, Opioid / Q000008:administration & dosage; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D059350:Chronic Pain / Q000175:diagnosis / Q000188:drug therapy*; D003078:Colchicine / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D054242:Emigrants and Immigrants; D010505:Familial Mediterranean Fever / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D005858:Germany; D006801:Humans; D008297:Male; D010147:Pain Measurement / Q000187:drug effects; D012651:Self Medication; D016896:Treatment Outcome; D014421:Turkey / Q000208:ethnology; D055815:Young Adult
chemical_list: D000700:Analgesics; D000701:Analgesics, Opioid; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000082:Acetaminophen; D003078:Colchicine