title: GC-MS combined with chemometric techniques for the quality control and original discrimination of Curcumae longae rhizome: analysis of essential oils.
abstract: Curcumae longae rhizome is a widely used traditional herb in many countries. Various geographical origins of this herb might lead to diversity or instability of the herbal quality. The objective of this work was to establish the chemical fingerprints for quality control and find the chemical markers for discriminating these herbs from different origins. First, chemical fingerprints of essential oil of 24 C. longae rhizome from four different geographical origins in China were determined by GC-MS. Then, pattern recognition techniques were introduced to analyze these abundant chemical data in depth; hierarchical cluster analysis was used to sort samples into groups by measuring their similarities, and principal component analysis and partial least-squares discriminate analysis were applied to find the main chemical markers for discriminating these samples. Curcumae longae rhizome from Guangxi province had the highest essential oil yield (4.32 ± 1.45%). A total of 46 volatile compounds were identified in total. Consistent results were obtained to show that C. longae rhizome samples could be successfully grouped according to their origins, and turmerone, ar-turmerone, and zingiberene were the characteristic components for discriminating these samples of various geographical origins and for quality control. This finding revealed that fingerprinting analysis based on GC-MS coupled with chemometric techniques could provide a reliable platform to discriminate herbs from different origins, which is a benefit for quality control.
authors: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
authors: Yichen
authors: Y
authors: Hu
authors: Weijun
authors: W
authors: Kong
authors: Xihui
authors: X
authors: Yang
authors: Liwei
authors: L
authors: Xie
authors: Jing
authors: J
authors: Wen
authors: Meihua
authors: M
authors: Yang
mesh_terms: D016000:Cluster Analysis; D030024:Curcuma / Q000737:chemistry*; D016002:Discriminant Analysis; D008401:Gas Chromatography-Mass Spectrometry; D009822:Oils, Volatile / Q000032:analysis*; D025341:Principal Component Analysis; D011786:Quality Control; D027343:Rhizome / Q000737:chemistry*
chemical_list: D009822:Oils, Volatile
keywords: Chemometrics; Curcumae longae rhizome; Essential oil; GC-MS; Quality control