title: Magnetic resonance imaging findings associated with lateral cerebral ventriculomegaly in English Bulldogs.
abstract: Multiple congenital or developmental anomalies associated with the central nervous system have been reported in English Bulldogs. The purpose of this retrospective study was to identify and describe the prevalence and MRI characteristics of these anomalies and their association with presence and degree of cerebral ventriculomegaly. Magnetic resonance imaging studies of 50 English Bulldogs were evaluated. Forty-eight dogs had some degree of cerebral ventriculomegaly, 27 of which had an otherwise normal brain. Presence of lateral ventriculomegaly was not significantly associated with presence of another intracranial lesion. Appearance of the septum pellucidum was variable, ranging from intact to incomplete or completely absent. The corpus callosum was subjectively thinned in all but three dogs, two of which had normal lateral ventricles. Fusion of the rostral colliculi was not found in any dog. A persistent craniopharyngeal canal was identified in one dog. Aqueductal stenosis caused by fusion of the rostral colliculi was not identified in any dog. Findings indicated that cerebral ventriculomegaly is a common finding in English Bulldogs with or without other intracranial lesions, aqueductal stenosis caused by fusion of the rostral colliculi is unlikely to be a common etiology leading to obstructive hydrocephalus, and a large craniopharyngeal canal is a rare finding that has unknown clinical significance at this time.
authors: Section of Radiology, Department of Clinical Studies School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104.
authors: Christopher T
authors: CT
authors: Ryan
authors: Eric N
authors: EN
authors: Glass
authors: Gabriela
authors: G
authors: Seiler
authors: Allison L
authors: AL
authors: Zwingenberger
authors: Wilfried
authors: W
authors: Mai
mesh_terms: D061085:Agenesis of Corpus Callosum / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology / Q000662:veterinary*; D000818:Animals; D004285:Dogs / Q000002:abnormalities*; D005260:Female; D006849:Hydrocephalus / Q000151:congenital / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000662:veterinary*; D008279:Magnetic Resonance Imaging / Q000662:veterinary*; D008297:Male; D015995:Prevalence; D011859:Radiography; D012189:Retrospective Studies; D012688:Septum Pellucidum / Q000002:abnormalities* / Q000000981:diagnostic imaging; D013045:Species Specificity; D013477:Superior Colliculi / Q000002:abnormalities* / Q000000981:diagnostic imaging
keywords: MRI; craniopharyngeal canal; english bulldog; hydrocephalus; ventriculomegaly