title: Markers of insulin resistance in a case of Launois-Bensaude syndrome.
abstract: Launois-Bensaude syndrome (benign symmetric lipoma-tosis) is a rare disease characterized by symmetric fat deposits localized in the cervical region, shoulders and proximal parts of upper and lower limbs. We present the case of a 63-year-old male who presented the typical location of fatty masses and a history of chronic alcoholism associated with elements defining the metabolic syndrome. The biological profile indicated high-atherogenic mixed dyslipidemia, high basal insulinemia (30 microU/ml), and multiple markers of insulin resistance (Reaven index, lipid accumulation product, homeostatic model, insulin sensitivity index, and modified glycemic curve following oral glucose load). The particularity of the presented case is the discordance between the severity of metabolic disturbances and their clinical expression, raising the question whether this patient's cardiometabolic risk is increased or rather lowered by the association of benign symmetric lipomatosis.
authors: Ist Medical Department, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa" - Iasi.
authors: Doina-Clementina
authors: DC
authors: Cojocaru
authors: Corina Dima
authors: CD
authors: Cozma
authors: Paraschiva
authors: P
authors: Postolache
mesh_terms: D001132:Arm / Q000473:pathology; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism*; D015992:Body Mass Index; D006801:Humans; D007328:Insulin / Q000097:blood*; D007333:Insulin Resistance; D008055:Lipids / Q000097:blood*; D008069:Lipomatosis, Multiple Symmetrical / Q000097:blood* / Q000150:complications / Q000473:pathology; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000150:complications / Q000473:pathology; D008875:Middle Aged; D009333:Neck / Q000473:pathology; D012782:Shoulder / Q000473:pathology; D013848:Thigh / Q000473:pathology
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D007328:Insulin; D008055:Lipids