title: Frequency of dengue virus infection in blood donors in Sistan and Baluchestan province in Iran.
abstract: Risk of dengue virus in the blood supply has been demonstrated in recent studies. In this paper, Chabahar in Sistan and Baluchestan province, south east of Iran, was selected for studying dengue infection because of its climatic and geographical situation in the middle of the transit way between East Asia and other countries. The blood samples were taken from volunteer healthy donors who were referred to the Chabahar Blood Center for blood donation. The presence of dengue virus (DENV) was studied by detecting IgG to DENV by enzyme linked immune sorbent assay (ELISA). Reactive ELISA results were confirmed by an immune flouorescence assay (IFA). According to the results, some of the healthy donors were infected by DENV, which could not been recognized in donor selection. Therefore, special attention should be paid to the criteria of donor selection and additional screening tests are recommended.
authors: Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran. Electronic address: Aghaie.a@gmail.com.
authors: Afsaneh
authors: A
authors: Aghaie
authors: Queensland University of Technology, Brisbane, Australia. Electronic address: J.aaskov@qut.edu.au.
authors: John
authors: J
authors: Aaskov
authors: Pasteur Institute of Iran, Tehran, Iran. Electronic address: Sadeghchinikar@yahoo.com.
authors: Sadegh
authors: S
authors: Chinikar
authors: Robert Koch Institute, Berlin, Germany. Electronic address: NiedrigM@rki.de.
authors: Matthias
authors: M
authors: Niedrig
authors: Iranian Blood Research and Fractionation Holding Company, Tehran, Iran. Electronic address: Banazadeh@yahoo.com.
authors: Soudabeh
authors: S
authors: Banazadeh
authors: Iranian Blood Research and Fractionation Holding Company, Tehran, Iran. Electronic address: Hkhorsandmp@yahoo.com.
authors: Hashem Khorsand
authors: HK
authors: Mohammadpour
mesh_terms: D001782:Blood Donors; D003715:Dengue / Q000097:blood / Q000453:epidemiology* / Q000821:virology*; D003716:Dengue Virus; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005455:Fluorescent Antibody Technique; D005843:Geography; D064368:Healthy Volunteers; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007492:Iran / Q000453:epidemiology; D008297:Male
chemical_list: D007074:Immunoglobulin G
keywords: Blood donor; Dengue virus; Iran