title: Adolescents' and young women's use of a microbicide surrogate product when receiving oral sex.
abstract: OBJECTIVE
  Genital herpes, which can be spread through oral sex, is an important target for microbicides. We examined episode-specific predictors of young women's receptive oral sex and of microbicide surrogate use.
  
  
  METHODS
  Longitudinal study.
  
  
  METHODS
  Participants were recruited to participate in a microbicide acceptability study from adolescent clinics and local colleges and through snowballing.
  
  
  METHODS
  Young women (ages 14 to 21 y) who reported sexual contact on at least 1 weekly phone interview (n = 181) were included from the larger sample of 208 young women.
  
  
  METHODS
  On weekly diary phone interviews, participants reported whether or not their last sexual contact included receptive oral sex and whether or not their last sexual contact included use of a microbicide surrogate.
  
  
  CONCLUSIONS
  Participants reported a total of 1042 episodes of sexual contact of which 311 included receptive oral sex and 354 included microbicide surrogate use. Being older, having sex for the first time with a partner, and having given oral sex were associated with having received oral sex during a sexual episode. Being older, being African American, and having discussed the microbicide surrogate with their partner were associated with having used the microbicide surrogate use during a sexual episode. These results indicate that oral sex should be considered in the design of clinical trials. Future studies need to evaluate ways to promote consistent microbicide use in the context of receiving oral sex as well as those factors (eg, taste, pleasure) which may serve as a barrier.
authors: Department of Pediatrics and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX. Electronic address: baauslan@utmb.edu.
authors: Beth A
authors: BA
authors: Auslander
authors: Department of Pediatrics, Columbia University Medical Center - College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY; Department of Population and Family Health, Columbia University Medical Center-Mailman School of Public Health and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY.
authors: Marina
authors: M
authors: Catallozzi
authors: Gray Davis Consulting, Raleigh-Durham, NC.
authors: Gray
authors: G
authors: Davis
authors: Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH.
authors: Paul A
authors: PA
authors: Succop
authors: Department of Pediatrics, Columbia University Medical Center - College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY.
authors: Lawrence R
authors: LR
authors: Stanberry
authors: Department of Pediatrics, Columbia University Medical Center - College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY; Department of Psychiatry, Columbia University Medical Center - College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY.
authors: Susan L
authors: SL
authors: Rosenthal
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D001741:Black or African American; D000367:Age Factors; D000890:Anti-Infective Agents; D003142:Communication; D004338:Drug Combinations; D005260:Female; D005990:Glycerol / Q000008:administration & dosage*; D006558:Herpes Genitalis / Q000517:prevention & control* / Q000635:transmission; D006801:Humans; D008055:Lipids / Q000008:administration & dosage; D008137:Longitudinal Studies; D008297:Male; D011092:Polyethylene Glycols / Q000008:administration & dosage*; D012725:Sexual Behavior / Q000208:ethnology; D012747:Sexual Partners; D014622:Vaginal Creams, Foams, and Jellies / Q000008:administration & dosage; D055815:Young Adult
chemical_list: D000890:Anti-Infective Agents; D004338:Drug Combinations; D008055:Lipids; C085472:Replens; D014622:Vaginal Creams, Foams, and Jellies; C052495:lubrin; D011092:Polyethylene Glycols; D005990:Glycerol
keywords: Adolescents; Genital herpes; Microbicides; Oral sex; Sexually transmitted infections