title: [Idiopathic inflammatory myopathies complicated with pneumonias: clinical characteristics and pathogen analysis].
abstract: OBJECTIVE
  To investigate the clinical characteristics, pathogen constitution and their tolerance to antibiotics in idiopathic inflammatory myopathies (IIM) patients complicated with pneumonia and the associated risk factors.
  
  
  METHODS
  The clinical data and pathogen test results of 93 IIM patients with pneumonia and 52 IIM patients without pneumonia (control group) were retrieved and compared.
  
  
  RESULTS
  Age of onset and interstitial lung disease were identified as risk factors associated with IIM complicated with pneumonia. Gram negative bacteria were the most common pathogen. Klebsiella pneumoniae was the most common bacteria and Candida albicans was the most common fungus causing infections in the IIM patients, which were relatively sensitive to the third- and fourth-generation of antibiotics such as cephalosporin, fluoroquinolones and aminoglycoside.
  
  
  CONCLUSIONS
  Older patients with interstitial lung disease are prone to having pneumonia, especially those caused by gram negative bacteria and other atypical pathogens. Timely and reasonable anti-infection treatment is essential.
authors: Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China.
authors: Yan
authors: Y
authors: Liang
authors: Rong
authors: R
authors: Deng
authors: Xin
authors: X
authors: Guo
authors: Chuan
authors: C
authors: Zuo
authors: Qi-Bing
authors: QB
authors: Xie
authors: Geng
authors: G
authors: Yin
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002176:Candida albicans / Q000302:isolation & purification; D005260:Female; D006090:Gram-Negative Bacteria / Q000302:isolation & purification*; D006801:Humans; D007711:Klebsiella pneumoniae / Q000302:isolation & purification; D016015:Logistic Models; D017563:Lung Diseases, Interstitial / Q000150:complications; D008297:Male; D008875:Middle Aged; D009220:Myositis / Q000150:complications*; D011014:Pneumonia / Q000150:complications* / Q000382:microbiology*; D012307:Risk Factors; D055815:Young Adult