title: [Correlation between ABCC11 gene single nucleotide polymorphism and the incidence of axillary osmidrosis in Chinese Han population].
abstract: OBJECTIVE
  To explore the relationship between ABCC11 gene single nucleotide polymorphism (SNP) and the incidence of axillary osmidrosis in Chinese Han population.
  
  
  METHODS
  The genotype of ABCC11 gene SNP at rs17822931 in 40 patients with axillary osmidrosis and 5 normal Han people was detected and analyzed by high resolution melt and gene sequencing.
  
  
  RESULTS
  The detection of the genotype of ABCC11 gene SNP at rs17822931 showed that: 37 of the 40 patients were GA genotype and the other 3 were GG genotype, while the 5 normal subjects were AA genotype.
  
  
  CONCLUSIONS
  SNP in ABCC11 is the genetic cause of axillary osmidrosis. GG or GA leads to axillary osmidrosis, while AA allele presents the absence of axillary osmidrosis.
authors: Department of Plastics and Cosmetic Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
authors: Yang
authors: Y
authors: Sun
authors: Jianhong
authors: J
authors: Long
authors: Yongjie
authors: Y
authors: Wang
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000235:genetics*; D000483:Alleles; D044466:Asian People; D001365:Axilla; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D015994:Incidence; D020641:Polymorphism, Single Nucleotide; D013543:Sweat Gland Diseases / Q000235:genetics*
chemical_list: C435500:ABCC11 protein, human; D018528:ATP-Binding Cassette Transporters