title: Synthesis, characterization and antimicrobial activity of certain novel aryl hydrazone pyrazoline-5-ones containing thiazole moiety.
abstract: OBJECTIVE
  The aim of this article is to synthesize, characterize and evaluate the antimicrobial activity of certain novel 3-methyl-5-oxo-4-(phenyl hydrazono)-4,5-dihydro-pyrazol-1-yl]-acetic acid N|-(4-substituted thiazol-2-yl)-hydrazides.
  
  
  METHODS
  The synthesized compounds were characterized by elemental analysis and IR, NMR and mass spectral data. The antimicrobial activity of novel compounds was evaluated by broth dilution method.
  
  
  RESULTS
  XVe, XVf and XVg have shown better antibacterial activity than other compounds of the series. XVa, XVc, XVd and XVe have shown better antifungal activity than the other compounds of the series.
  
  
  CONCLUSIONS
  All compounds were found to exhibit fair degree of antimicrobial activity.
authors: Sri Krishnadevaraya University, Anantapur, A.P., India.
authors: Maliki Reddy Dastagiri
authors: MR
authors: Reddy
authors: Aluru Raghavendra Guru
authors: AR
authors: Prasad
authors: Yadati Narasimha
authors: YN
authors: Spoorthy
authors: Lakshmana Rao Krishna Rao
authors: LR
authors: Ravindranath
keywords: Antimicrobial activity; Elemental analysis; Pyrazoline-5-ones; Spectral analysis; Synthesis; Thiazole