title: Ischemic heart disease in systemic inflammatory diseases. An appraisal.
abstract: Systemic inflammatory diseases are inflammatory syndromes that are associated with increased cardiovascular morbidity and mortality. The link between inflammatory and cardiovascular diseases can be attributed to coexistence of classical risk factors and of inflammatory mechanisms activated in systemic inflammatory diseases and involving the immune system. Yet, clinical implications of these findings are not entirely clear and deeper knowledge and awareness of cardiac involvement in inflammatory diseases are necessary. The aims of this review are to summarize cardiac involvement in systemic inflammatory diseases and to identify areas where evidence is currently lacking that deserve further investigation in the future.
authors: SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy.
authors: Paola
authors: P
authors: Gargiulo
authors: Advanced Biomedical Sciences, Federico II University, Naples, Italy.
authors: Fabio
authors: F
authors: Marsico
authors: Advanced Biomedical Sciences, Federico II University, Naples, Italy.
authors: Antonio
authors: A
authors: Parente
authors: Advanced Biomedical Sciences, Federico II University, Naples, Italy.
authors: Stefania
authors: S
authors: Paolillo
authors: Advanced Biomedical Sciences, Federico II University, Naples, Italy.
authors: Milena
authors: M
authors: Cecere
authors: Advanced Biomedical Sciences, Federico II University, Naples, Italy.
authors: Laura
authors: L
authors: Casaretti
authors: Advanced Biomedical Sciences, Federico II University, Naples, Italy.
authors: Angela Maria
authors: AM
authors: Pellegrino
authors: Advanced Biomedical Sciences, Federico II University, Naples, Italy.
authors: Tiziana
authors: T
authors: Formisano
authors: Advanced Biomedical Sciences, Federico II University, Naples, Italy.
authors: Irma
authors: I
authors: Fabiani
authors: SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy; Department of Studies of Institutions and Territorial Systems, University of Naples Parthenope, Naples, Italy.
authors: Andrea
authors: A
authors: Soricelli
authors: Advanced Biomedical Sciences, Federico II University, Naples, Italy.
authors: Bruno
authors: B
authors: Trimarco
authors: Advanced Biomedical Sciences, Federico II University, Naples, Italy. Electronic address: fpperron@unina.it.
authors: Pasquale
authors: P
authors: Perrone-Filardi
mesh_terms: D050197:Atherosclerosis / Q000453:epidemiology / Q000276:immunology* / Q000503:physiopathology; D001327:Autoimmune Diseases / Q000453:epidemiology / Q000276:immunology* / Q000503:physiopathology; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000276:immunology* / Q000503:physiopathology; D006801:Humans; D017202:Myocardial Ischemia / Q000453:epidemiology / Q000276:immunology* / Q000503:physiopathology; D012216:Rheumatic Diseases / Q000453:epidemiology / Q000276:immunology* / Q000503:physiopathology; D012307:Risk Factors
keywords: Atherosclerosis; Coronary artery disease; Immune system; Systemic inflammatory disease