title: Secondary syphilis: a case mimicking erythema multiforme clinically and pathologically.
abstract: Secondary syphilis, the hematogenous spread of Treponema pallidum, usually occurs 4-10 weeks after initial exposure. The skin is involved in 70% of cases, with maculopapular, vesiculobullous, and ulcerative morphologies possible at presentation, making the diagnosis of secondary syphilis challenging given its ability to mimic many other conditions. We present an atypical case of secondary syphilis that closely resembled erythema multiforme (EM) clinically and histologically.
authors: Baylor College of Medicine.
authors: Apphia
authors: A
authors: Wang
authors: Sara
authors: S
authors: Risner-Rumohr
authors: Paul
authors: P
authors: Rodriguez-Waitkus
authors: Harry
authors: H
authors: Dao
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004892:Erythema Multiforme / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010400:Penicillin G / Q000627:therapeutic use; D013587:Syphilis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D014210:Treponema pallidum / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D010400:Penicillin G