title: Synthesis of 3-((trifluoromethyl)thio)indoles via a reaction of 2-alkynylaniline with trifluoromethanesulfanylamide.
abstract: 3-((Trifluoromethyl)thio)indoles can be synthesized by a palladium(II)-catalyzed reaction of 2-alkynylaniline with trifluoromethanesulfanylamide in the presence of bismuth(III) chloride. The presence of bismuth(III) chloride is crucial for the success of this transformation, which activates the trifluoromethanesulfanylamide during the reaction.
authors: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China. jie_wu@fudan.edu.cn.
authors: Jie
authors: J
authors: Sheng
authors: Shaoyu
authors: S
authors: Li
authors: Jie
authors: J
authors: Wu
mesh_terms: D000577:Amides / Q000737:chemistry*; D000814:Aniline Compounds / Q000737:chemistry*; D001729:Bismuth / Q000737:chemistry; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry
chemical_list: D000577:Amides; D000814:Aniline Compounds; D002712:Chlorides; D007211:Indoles; C534543:bismuth trichloride; D010165:Palladium; C023650:aniline; D001729:Bismuth