title: Meta-selective C-H functionalization using a nitrile-based directing group and cleavable Si-tether.
abstract: A nitrile-based template that enables meta-selective C-H bond functionalization was developed. The template is applicable to a range of substituted arenes and tolerates a variety of functional groups. The directing group uses a silicon atom for attachment, allowing for a facile introduction/deprotection strategy increasing the synthetic practicality of this template.
authors: Boston College , 2609 Beacon Street Chestnut Hill, Massachusetts 02467.
authors: Sunggi
authors: S
authors: Lee
authors: Hyelee
authors: H
authors: Lee
authors: Kian L
authors: KL
authors: Tan
mesh_terms: D002244:Carbon / Q000737:chemistry; D006860:Hydrogen Bonding; D009570:Nitriles / Q000737:chemistry*
chemical_list: D009570:Nitriles; D002244:Carbon