title: Treatment outcomes of open pelvic fractures associated with extensive perineal injuries.
abstract: BACKGROUND
  The main causes of death in patients with open pelviperineal injuries are uncontrollable bleeding and pelvic sepsis. The aim of this study was to evaluate the management outcomes of open pelvic fractures associated with extensive perineal injuries.
  
  
  METHODS
  We retrospectively studied 15 cases with open pelvic fractures associated with extensive perineal injuries (urethral and anal canal laceration) admitted between August 2006 and September 2010. Mechanism of injury, Injury Severity Score, associated injuries, hemodynamic status on arrival, resuscitation and transfusion requirements, operative techniques, intra- and postoperative complications, length of intensive care unit and hospital stay, and mortality were recorded in a computerised database for further evaluation and analysis.
  
  
  RESULTS
  The male to female ratio was 12:3 with an average age of 38.6 years (ranged, 11 to 65 years). The average packed red blood cell units used were 8 units (ranged, 4 to 21 units). All patients were initially transferred to the operating room for colostomy, radical debridement and fixation of the pelvic fracture by an external fixator. One patient had acute renal failure, which improved with medical treatment and 2 patients (13.3%) died, one with type III anteroposterior compression fracture due to hemorrhagic shock and the other due to septicemia.
  
  
  CONCLUSIONS
  Open pelvic fractures with extensive perineal injuries are associated with high mortality rates. Early diagnosis and appropriate treatment, including reanimation, colostomy, cystostomy, vigorous and repeated irrigation and debridement, and fixation by an external fixator can improve the outcomes and reduce the mortality rate.
authors: Orthopedic Department, Orthopedic Research Center, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
authors: Ebrahim Ghayem
authors: EG
authors: Hasankhani
authors: Farzad
authors: F
authors: Omidi-Kashani
mesh_terms: D000059:Accidents; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003125:Colostomy; D005260:Female; D005597:Fractures, Open / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010384:Pelvic Bones / Q000293:injuries* / Q000601:surgery*; D010502:Perineum / Q000293:injuries* / Q000601:surgery*; D012189:Retrospective Studies; D012771:Shock, Hemorrhagic; D016896:Treatment Outcome; D055815:Young Adult
keywords: Open fracture; Pelvic fracture; Perineal injury