title: Does hyperglycemia in pregnancy change fetal kidney growth? A longitudinal prospective study.
abstract: OBJECTIVE
  To measure fetal renal volume in normoglycemic and hyperglycemic pregnancies.
  
  
  METHODS
  A longitudinal prospective study was conducted and included 92 hyperglycemic and 339 normoglycemic pregnant women attended at the prenatal service of a hospital from Rio de Janeiro State. Ultrasound examinations were performed to estimate gestational age at baseline and the kidney volume was estimated using the prolate ellipsoid volume equation.
  
  
  RESULTS
  Fetal kidney volume growth between normoglycemic and hyperglycemic pregnancies are significantly different. The fetal kidney volume growth in pregnancy is positively correlated with gestational age explained by these predictor equations, by group: normal renal volume = exp (6.186 + 0.09 × gestational week); hyperglycemic renal volume = exp (6.978 + 0.071 × gestational week) and an excessive growth pattern for hyperglycemic pregnancies may be established according to gestational age.
  
  
  CONCLUSIONS
  This is important for early detection of abnormalities in pregnancy, particularly in diabetic mothers.
authors: Haroldo Millet
authors: HM
authors: Neves
authors: Fábio
authors: F
authors: Sgarbosa
authors: Iracema Mattos Paranhos
authors: IM
authors: Calderon
authors: Luana Schneider
authors: LS
authors: Vianna
authors: Ana Carolina Monteiro
authors: AC
authors: Santini
authors: Lino
authors: L
authors: Sieiro Netto
authors: Adriano
authors: A
authors: Dias
mesh_terms: D005260:Female; D047109:Fetal Development; D005865:Gestational Age; D006801:Humans; D006943:Hyperglycemia; D007668:Kidney / Q000196:embryology*; D008137:Longitudinal Studies; D011247:Pregnancy; D011248:Pregnancy Complications; D011446:Prospective Studies