title: Homology between the proteins encoded by tobacco mosaic virus and two tricornaviruses.
abstract: A comparison was made of the amino acid sequences of the proteins encoded by RNAs 1 and 2 of alfalfa mosaic virus (A1MV) and brome mosaic virus (BMV), and the 126K and 183K proteins encoded by tobacco mosaic virus (TMV). Three blocks of extensive homology of about 200 to 350 amino acids each were observed. Two of these blocks are located in the A1MV and BMV RNA 1 encoded proteins and the TMV encoded 126K protein; they are situated at the N-terminus and C-terminus, respectively. The third block is located in the A1MV and BMV RNA 2 encoded proteins and the C-terminal part of the TMV encoded 183K protein. These homologies are discussed with respect to the functional equivalence of these putative replicase proteins and a possible evolutionary connection between A1MV, BMV and TMV.
authors: Department of Biochemistry, State University of Leiden, P.O. Box 9505, 2300 RA, Leiden, The Netherlands.
authors: B J
authors: BJ
authors: Cornelissen
authors: J F
authors: JF
authors: Bol