title: Synthesis and characterization of fluoro-modified polypropylene films for inhibition of biofilm formation.
abstract: Surface hydroperoxide-conjugated polypropylene (PP) films were prepared by optimal ozonolysis processing of the films. These hydroperoxide-conjugated groups were then used as initiators at room temperature for redox graft polymerization of the fluoro vinylic monomer 1H,1H-heptaflourobutyl methacrylate (HFBM). The ozonolysis process allows, on one hand, for the formation of the desired hydroperoxide-conjugated groups while, on the other hand, leads to an undesired degradation of the PP. The ozone treatment time was therefore optimized to obtain sufficient hydroperoxide groups for graft polymerization, while maintaining the mechanical strength of the films, which was barely affected. The resulting PP-PolyHFBM (PP-PHFBM) films were characterized by methods such as AFM, ATR, TGA, contact angle goniometry and XPS. The antibiofilm properties of the PP-PHFBM films were evaluated, using two bacterial strains. An 86% inhibition was observed for the Gram-negative Escherichia coli, and a 37% inhibition was observed for the Gram-positive Listeria.
authors: The Institute of Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel. Electronic address: innalaitman@gmail.com.
authors: Inna
authors: I
authors: Laitman
authors: The Mina and Everard Goodman Faculty of Life Sciences, The Institute for Advanced Materials and Nanotechnology, Bar-Ilan University, Ramat-Gan 52900, Israel. Electronic address: natan.michal@gmail.com.
authors: Michal
authors: M
authors: Natan
authors: The Mina and Everard Goodman Faculty of Life Sciences, The Institute for Advanced Materials and Nanotechnology, Bar-Ilan University, Ramat-Gan 52900, Israel. Electronic address: Ehud.Banin@biu.ac.il.
authors: Ehud
authors: E
authors: Banin
authors: The Institute of Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel. Electronic address: shlomo.margel@mail.biu.ac.il.
authors: Shlomo
authors: S
authors: Margel
mesh_terms: D018441:Biofilms / Q000187:drug effects*; D002152:Calorimetry, Differential Scanning; D004926:Escherichia coli / Q000187:drug effects / Q000502:physiology; D017611:Fluorine Compounds / Q000138:chemical synthesis* / Q000494:pharmacology*; D006861:Hydrogen Peroxide / Q000737:chemistry; D008087:Listeria / Q000187:drug effects / Q000502:physiology; D018625:Microscopy, Atomic Force; D010084:Oxidation-Reduction / Q000187:drug effects; D058105:Polymerization / Q000187:drug effects; D011126:Polypropylenes / Q000138:chemical synthesis* / Q000494:pharmacology*; D017550:Spectroscopy, Fourier Transform Infrared; D013818:Thermogravimetry; D014867:Water / Q000737:chemistry
chemical_list: D017611:Fluorine Compounds; D011126:Polypropylenes; D014867:Water; D006861:Hydrogen Peroxide
keywords: Biofilm; Graft polymerization; Ozonolysis; Surface modification