title: Phialophora verrucosa as a cause of deep infection following total knee arthroplasty.
abstract: Deep joint infection is one of the most feared complications following total joint replacement. Prompt diagnosis and treatment with 2-staged revision is currently the gold standard for treatment. We report a case of a chronic infection following total knee replacement caused by Phialophora verrucosa, a form of dematiaceous fungus. The patient was treated with an antibiotic spacer and a course of oral anti-fungal agents. To our knowledge, there have been no reported cases of P verrucosa as a cause of infection in hip or knee arthroplasty.
authors: Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY. Jason.hochfelder@gmail.com.
authors: Jason
authors: J
authors: Hochfelder
authors: Joseph
authors: J
authors: Fetto
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy* / Q000382:microbiology; D020370:Osteoarthritis, Knee / Q000601:surgery; D010676:Phialophora / Q000302:isolation & purification*; D016459:Prosthesis-Related Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents