title: Enantioselective synthesis of diaryl aziridines using tetrahydrothiophene-based chiral sulfides as organocatalysts.
abstract: This work describes catalytic and asymmetric aziridinations (15 examples, 95-98% ee) of benzyl bromide and imines via the imino Corey-Chaykovsky reaction using (thiolan-2-yl)diarylmethanol benzyl ether as an organocatalyst. The catalyst and analogues thereof were prepared through an expeditious and efficient synthetic route featuring a double nucleophilic substitution and Shi epoxidation as key steps.
authors: Department of Chemistry, National Taiwan Normal University, 162, Heping East Road Section 1, Taipei 10610, Taiwan.
authors: Meng-Ting
authors: MT
authors: Huang
authors: Hsin-Yi
authors: HY
authors: Wu
authors: Rong-Jie
authors: RJ
authors: Chein