title: Regioselectivity in the nucleophile trapping of arynes: the electronic and steric effects of nucleophiles and substituents.
abstract: The regioselectivity in nucleophile trapping is investigated with arynes generated directly from bis-1,3-diynes. The regioselectivity is profoundly influenced by not only the nature of nucleophiles but also the substituents on the arynes, which is the consequence of both the unfavorable steric interaction between the incoming nucleophile and the nearby substituent and the inherent electronic bias induced by different substituents on the arynes.
authors: Department of Chemistry, University of Illinois at Chicago , 845 West Taylor Street, Chicago, Illinois 60607, United States.
authors: Rajdip
authors: R
authors: Karmakar
authors: Sang Young
authors: SY
authors: Yun
authors: Kung-Pern
authors: KP
authors: Wang
authors: Daesung
authors: D
authors: Lee