title: Isolated oral Kaposi sarcoma in an HIV-negative patient: a case report.
abstract: BACKGROUND
  Kaposi sarcoma is a well-known vascular tumor first described by Moriz Kaposi in 1872. Oral involvement is seen as an AIDS-related malignant neoplasm but is rarely described in HIV-negative and non-immunosuppressed individuals.
  
  
  METHODS
  We report a case of oral Kaposi sarcoma in a 75-year-old, HIV-negative woman. Diagnosis was achieved according to clinical, histopathological and positive polymerase chain reaction for human herpes virus 8. The tumor was surgically excised and no recurrence was detected in the following 6 months.
  
  
  CONCLUSIONS
  Oral Kaposi sarcoma is rare in HIV-negative patients and is associated with HHV-8 infection. Lesions are usually solitary and can be treated surgically. It should be included in the differential diagnoses of oral lesions that are clinically suspicious and resistant to therapy.
authors: Department of Dermatology, Andrology and Sexually Transmitted Diseases, Faculty of Medicine, Menoufiya University, Shebin Elkoom, Egypt.
authors: Mohamed Abdel Wahed
authors: MA
authors: Gaber
authors: Department of Dermatology, Andrology and Sexually Transmitted Diseases, Faculty of Medicine, Menoufiya University, Shebin Elkoom, Egypt.
authors: Ola Ahmed
authors: OA
authors: Bakry
authors: Department of Dermatology, Andrology and Sexually Transmitted Diseases, Faculty of Medicine, Menoufiya University, Shebin Elkoom, Egypt.
authors: Wafaa Ahmed
authors: WA
authors: Shehata
mesh_terms: D000368:Aged; D005260:Female; D018023:HIV Seronegativity; D019288:Herpesvirus 8, Human / Q000302:isolation & purification*; D006801:Humans; D009062:Mouth Neoplasms / Q000473:pathology* / Q000601:surgery / Q000821:virology*; D012514:Sarcoma, Kaposi / Q000473:pathology* / Q000601:surgery / Q000821:virology*