title: Validated spectrophotometric quantification of aripiprazole in pharmaceutical formulations by using multivariate technique.
abstract: OBJECTIVE
  An accurate and precise UV spectrophotometric method with multivariate calibration technique for the determination of aripiprazole in pharmaceutical formulations has been described.
  
  
  METHODS
  This technique is based on the use of the linear regression equations by using the relationship between concentration and absorbance at five different wavelengths. The aripiprazole shows absorption maxima at 255 nm and obeyed Beer's law in the range of 5-30 µg/mL.
  
  
  RESULTS
  The results were treated statistically and were found highly accurate, precise and reproducible. This statistical approach gives optimum results for the eliminating fluctuations coming from instrumental or experimental conditions.
  
  
  CONCLUSIONS
  It was concluded that the proposed method is simple, easy to apply, economical and could be used as an alternative to the existing spectrophotometric and non-spectrophotometric methods for the routine analysis of aripiprazole in pharmaceutical formulations.
authors: Department of Pharmaceutical Analysis, Malla Reddy College of Pharmacy, Maisammaguda, Dhulapally, Secunderabad, Andhra Pradesh, India-500014.
authors: Kandikonda
authors: K
authors: Sandeep
authors: Madhusudhanareddy
authors: M
authors: Induri
authors: Muvvala
authors: M
authors: Sudhakar
keywords: Aripiprazole; Multivariate Technique; Tablets; UV-Spectrophotometry