title: [The system of assessment of the severity of ultrasound epilepsy in rats].
abstract: The method of induction of epileptic reactions in rats by ultrasound (24.3 kHz; 116dB) and the system of severity estimation of epileptic reaction was developed. Ultrasound--frequency above 20 kHz--absolutely silent for a person, may cause epileptic reaction in 3-9% of the rats. The possibility of using ultrasound--induced epilepsy in rats to evaluate anticonvulsant activity of drugs it is shown.
authors: R A
authors: RA
authors: Kopaladze
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000627:therapeutic use; D002220:Carbamazepine / Q000627:therapeutic use; D004827:Epilepsy / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D051381:Rats; D013016:Sound / Q000009:adverse effects*
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine