title: Antibacterial prenylbenzoic acid derivatives from Anodendron formicinum.
abstract: A phytochemical investigation on the stems of Anodendron formicinum led to the isolation of eight prenylbenzoic acid derivatives. Three of these were new compounds, designated as formicinuosides A (1), B (2), and C (3). Their structures were elucidated on the basis of extensive spectroscopic analysis, as well as by comparison with the reported spectroscopic data. This is the first report of chemical constituents from A. formicinum and their antimicrobial activities. Among the isolated compounds, compounds 4, 6 and 8 showed significant antibacterial activities against Providensia smartii with MIC values of 0.781 μg/mL. Moreover, compound 8 showed remarkable antibacterial activity against Escherichia coli with MIC value of 0.781 μg/mL.
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, PR China; University of Chinese Academy of Science, Beijing 100049, PR China.
authors: Xu-Jie
authors: XJ
authors: Qin
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, PR China; Department of Biochemistry, Laboratory of Phytobiochemistry and Medicinal Plants Study, Faculty of Science, University of Yaoundé 1, Yaoundé P.O. Box 812, Cameroon.
authors: Paul-Keilah
authors: PK
authors: Lunga
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, PR China.
authors: Yun-Li
authors: YL
authors: Zhao
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, PR China; University of Chinese Academy of Science, Beijing 100049, PR China.
authors: Jiang-Ling
authors: JL
authors: Li
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, PR China; University of Chinese Academy of Science, Beijing 100049, PR China.
authors: Xing-Wei
authors: XW
authors: Yang
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, PR China. Electronic address: liuyaping@mail.kib.ac.cn.
authors: Ya-Ping
authors: YP
authors: Liu
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, PR China. Electronic address: xdluo@mail.kib.ac.cn.
authors: Xiao-Dong
authors: XD
authors: Luo
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029062:Apocynaceae / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects*; D019817:Benzoic Acid / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D018547:Plant Stems
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D019817:Benzoic Acid
keywords: Anodendron formicinum; Antibacterial activity; Apocynaceae; Prenylbenzoic acid derivatives