title: Complete androgen insensitivity syndrome with a Sertoli-Leydig cell tumor.
abstract: BACKGROUND
  The complete androgen insensitivity (testicular feminization) syndrome was described in phenotypic females with 46XY karyotype, presenting with primary amenorrhea, adequate breast development, and absent or sparse pubic or axillary hair. Gonads consist usually of seminiferous tubules without spermatogenesis.
  
  
  METHODS
  We report the case of a 15-year-old girl with testicular feminization since age 4. She was admitted to surgically remove the testes from the inguinal canal. Microscopic examination of the left testis revealed a Sertoli-Leydig cell tumor and the draft of fallopian tube with adjacent seminiferous tubules.
  
  
  CONCLUSIONS
  These patients have a 5%-10% risk of developing germ cell tumors. Sertoli-Leydig cell tumors are uncommon neoplasms, usually benign in testicular feminization syndrome.
authors: Department of Obstetrics and Gynaecology, Military Hospital Mohamed V, CHU Ibn Sina, Rabat, Morocco. Electronic address: houdhoudf14@gmail.com.
authors: Houda
authors: H
authors: Fagouri
authors: Department of Obstetrics and Gynaecology, Military Hospital Mohamed V, CHU Ibn Sina, Rabat, Morocco.
authors: Driss Rahali
authors: DR
authors: Moussaoui
authors: Department of Obstetrics and Gynaecology, Military Hospital Mohamed V, CHU Ibn Sina, Rabat, Morocco.
authors: Jaoud
authors: J
authors: Kouach
authors: Department of Obstetrics and Gynaecology, Military Hospital Mohamed V, CHU Ibn Sina, Rabat, Morocco.
authors: Abdelah
authors: A
authors: Babahabib
authors: Department of Histopathology, Military Hospital Mohamed V, CHU Ibn Sina, Rabat, Morocco.
authors: Mohamed
authors: M
authors: Oukabli
authors: Department of Urology, Military Hospital Mohamed V, CHU Ibn Sina, Rabat, Morocco.
authors: Ahmed
authors: A
authors: Ameur
authors: Department of Histopathology, Military Hospital Mohamed V, CHU Ibn Sina, Rabat, Morocco.
authors: Abderrahmane
authors: A
authors: Albouzidi
authors: Department of Obstetrics and Gynaecology, Military Hospital Mohamed V, CHU Ibn Sina, Rabat, Morocco.
authors: Mohamed
authors: M
authors: Dehayni
mesh_terms: D000293:Adolescent; D013734:Androgen-Insensitivity Syndrome / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D009919:Orchiectomy; D018310:Sertoli-Leydig Cell Tumor / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D013736:Testicular Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery
keywords: Androgen insensitivity syndrome; Orchidectomy; Sertoli-Leydig cell tumors; Testicular feminization