title: [Red cell transfusion and long-term survival in non-complicated heart surgery].
abstract: OBJECTIVE
  A study was made to explore the possible association between the perioperative transfusion of 1 - 2 red blood cell units and in-hospital morbidity, 30-day mortality, and long-term survival in patients undergoing heart surgery.
  
  
  METHODS
  A prospective observational study was carried out.
  
  
  METHODS
  The ICU of a university hospital.
  
  
  METHODS
  All patients over 17 years of age that underwent heart surgery and were admitted to the ICU between November 2002 and December 2009 were included. Those patients who did not (n=703) and those who did (n=959) receive the perioperative transfusion of 1 - 2 red blood cell units were assessed.
  The endpoints were the effect of transfusion on both hospital morbidity and on 30-day mortality. In addition, all patients discharged alive from hospital until 31 December 2011 were subjected to follow-up. The association between transfusion and survival was assessed by means of the Kaplan-Meier method. Cox proportional hazards models were used to assess factors associated with long-term survival.
  
  
  RESULTS
  The frequency of both cardiac and non-cardiac perioperative complications was higher in patients receiving transfusion. The 30-day mortality rate was higher in those who received transfusion (1% vs 0.1%, P=.02). Preoperative anemia was associated with a more intensive use of transfusion. Red blood cell transfusion was not found to be a risk factor for long-term mortality (hazar ratio=1.4, 95%CI 0.9-2.1).
  
  
  CONCLUSIONS
  The perioperative transfusion of 1 - 2 red blood cell units in patients undergoing heart surgery increases both hospital morbidity and the 30-day mortality rate, but does not increase long-term mortality.
authors: Servicio de Medicina Intensiva, Servicio de Cirugía Cardíaca, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España. Electronic address: rierasagrera@gmail.com.
authors: M
authors: M
authors: Riera
authors: Servicio de Medicina Intensiva, Servicio de Cirugía Cardíaca, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España.
authors: J
authors: J
authors: Ibáñez
authors: Servicio de Medicina Intensiva, Servicio de Cirugía Cardíaca, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España.
authors: M
authors: M
authors: Molina
authors: Servicio de Medicina Intensiva, Servicio de Cirugía Cardíaca, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España.
authors: R
authors: R
authors: Amézaga
authors: Servicio de Medicina Intensiva, Servicio de Cirugía Cardíaca, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España.
authors: A
authors: A
authors: Colomar
authors: Servicio de Medicina Intensiva, Servicio de Cirugía Cardíaca, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España.
authors: A
authors: A
authors: Carrillo
authors: Servicio de Medicina Intensiva, Servicio de Cirugía Cardíaca, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España.
authors: O
authors: O
authors: Bonnín
authors: Servicio de Medicina Intensiva, Servicio de Cirugía Cardíaca, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España.
authors: J I
authors: JI
authors: Sáez de Ibarra
authors: Servicio de Medicina Intensiva, Servicio de Cirugía Cardíaca, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España.
authors: C
authors: C
authors: Campillo-Artero
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006348:Cardiac Surgical Procedures / Q000401:mortality; D003327:Coronary Disease / Q000401:mortality / Q000601:surgery*; D017707:Erythrocyte Transfusion / Q000706:statistics & numerical data*; D005260:Female; D006349:Heart Valve Diseases / Q000401:mortality / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015996:Survival Rate; D013997:Time Factors
keywords: Cardiac surgical procedures; Cirugía cardíaca; Cuidados intensivos; Intensive care; Morbidity; Morbilidad; Mortalidad; Mortality; Red blood cell transfusion; Transfusión de hematíes