title: [To explore the safety testing evaluation index of breast-feeding by hepatitis B-positive mothers].
abstract: OBJECTIVE
  To explore the safety testing evaluation index of breast-feeding by hepatitis B-positive mothers.
  
  
  METHODS
  HBV DNA from serum and breast milk of 252 hepatitis B-positive mothers were detected with the real-time quantitative PCR.
  
  
  RESULTS
  The total positive rate of HBV DNA in serum had no difference with that in breast milk in hepatitis B-positive mothers (P > 0.05). The positive rate of HBV DNA in serum and breast milk of positive HBeAg were significantly higher than that of hepatitis B-positive mothers with negative HBeAg (P < 0.01).
  
  
  CONCLUSIONS
  To detecte HBeAg and HBV DNA in serum and breast milk have important significance for guiding of breast feeding of hepatitis B-positive mothers.
authors: Huangyan Maternal and Child Health Hospital, Taizhou 318020, China.
authors: Wen-Ping
authors: WP
authors: Zhang
authors: He-Ying
authors: HY
authors: Shi
authors: Cai-Bin
authors: CB
authors: Li
authors: Qi-Hong
authors: QH
authors: Li
authors: Peng
authors: P
authors: Du
mesh_terms: D000328:Adult; D001942:Breast Feeding; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006509:Hepatitis B / Q000821:virology*; D006513:Hepatitis B e Antigens / Q000032:analysis; D006801:Humans; D008895:Milk, Human / Q000821:virology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology*
chemical_list: D004279:DNA, Viral; D006513:Hepatitis B e Antigens