title: Effects of the topical hemostatic agent Ankaferd Blood Stopper on the incidence of alveolar osteitis after surgical removal of an impacted mandibular third molar.
abstract: BACKGROUND
  Alveolar osteitis (AO) is a commonly seen post-operative complication during the wound-healing period after permanent tooth extraction or surgical removal of impacted third molar teeth.
  
  
  OBJECTIVE
  The aim of this clinical study was to evaluate the effects of administration of the topical hemostatic agent Ankaferd Blood Stopper (ABS) into the socket on AO formation after impacted mandibular third molar extraction.
  
  
  METHODS
  Bilaterally, 100 half-impacted mandibular third molars were extracted in 50 patients. Then, 1.0 mL ABS was administered to achieve hemostasis in one half of the sockets and as a control, the other half was irrigated with 1.0 mL physiological serum after surgery.
  
  
  RESULTS
  There was no statistically significant difference in terms of AO formation ( P > 0.05) between the extraction sites. However, the postoperative pain in ABS administration sites was higher than in the other sites for the first 2 days after surgery ( P < 0.05).
  
  
  CONCLUSIONS
  The results showed that ABS administration did not increase the incidence of AO formation. Thus, ABS can be used safely for hemostasis after impacted mandibular third molar surgery.
authors: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Abant Izzet Baysal University, Bolu, Turkey.
authors: M
authors: M
authors: Tek
authors: I
authors: I
authors: Akkas
authors: O
authors: O
authors: Toptas
authors: F
authors: F
authors: Ozan
authors: I
authors: I
authors: Sener
authors: C
authors: C
authors: Bereket
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D004311:Double-Blind Method; D004368:Dry Socket / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D005260:Female; D005500:Follow-Up Studies; D006489:Hemostatic Techniques; D006801:Humans; D015994:Incidence; D008297:Male; D008964:Molar, Third / Q000601:surgery*; D010936:Plant Extracts / Q000008:administration & dosage*; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D014081:Tooth Extraction / Q000009:adverse effects* / Q000379:methods; D014095:Tooth, Impacted / Q000382:microbiology / Q000601:surgery*; D014421:Turkey / Q000453:epidemiology; D014945:Wound Healing; D055815:Young Adult
chemical_list: D010936:Plant Extracts; C539751:ankaferd blood stopper