title: Reduction mammaplasty and mastopexy in previously irradiated breasts.
abstract: BACKGROUND
  Little data exist on the safety of elective breast surgery following breast conservation therapy.
  
  
  OBJECTIVE
  The authors evaluate their experience performing reduction mammaplasties and mastopexies in previously irradiated breasts.
  
  
  METHODS
  A retrospective chart review was conducted of all reduction mammaplasties and mastopexies in previously irradiated breasts performed by the 2 senior authors (MYN and SLS) from 1995 to 2012 (n = 18). Patient records were analyzed for demographics, perioperative and postoperative details, and complications.
  
  
  RESULTS
  During the study period, 12 reduction mammaplasties and 6 mastopexies were performed on breasts previously treated with breast conservation therapy. The average study participant age was 49.5 years, and average body mass index was 29. Average preoperative bra cup size was D/DD. One patient was a former smoker; 17 were nonsmokers. Eleven of the 18 patients had been previously treated with chemotherapy; average time between radiation therapy and surgery was 2.5 years. Average specimen weight in the 12 reduction mammaplasties was 623 g. Twenty-two percent (n = 4) of patients experienced a total of 5 minor complications; none required a return to the operating room. One patient (6%) experienced a major complication resulting in approximately 50% loss of breast tissue, which was reconstructed with a latissimus dorsi musculocutaneous flap. Seventeen patients (94%) had successful outcomes with preoperative goals achieved.
  
  
  CONCLUSIONS
  In the previously irradiated breast, reduction mammaplasty and mastopexy should be approached with extra caution, but the surgeries may still be safely and successfully performed.
  
  
  METHODS
  4.
authors: Department of Plastic Surgery, Georgetown University Hospital, Washington, DC.
authors: Scott L
authors: SL
authors: Spear
authors: Samir S
authors: SS
authors: Rao
authors: Ketan M
authors: KM
authors: Patel
authors: Maurice Y
authors: MY
authors: Nahabedian
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000009:adverse effects; D015412:Mastectomy, Segmental / Q000009:adverse effects; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
keywords: breast conservation therapy; breast irradiation; breast surgery; mastopexy; radiation; reduction mammaplasty; wound healing