title: Effects of bacterial melanin on movement, posture, and skilled balancing deficits after unilateral destruction of substantia nigra pars compacta in rats.
abstract: Sixteen adult male rats were initially trained to an instrumental conditioned reflex (ICR) and subjected to unilateral destruction of substantia nigra pars compacta. Part of the animals was injected with bacterial melanin solution on the next day of destruction. The other 8 rats served as the control group. Recovery rates for ICR and dynamics of paralyzed hindlimb movements were studied in both groups. Conditioned reflex and contralateral to lesion hindlimb movements recovered faster in rats injected with bacterial melanin after the destruction.
authors: a Department of Kinesiology , Armenian State Institute of Physical Education , Yerevan.
authors: T R
authors: TR
authors: Petrosyan
authors: O V
authors: OV
authors: Gevorkyan
authors: A S
authors: AS
authors: Hovsepyan
mesh_terms: D000818:Animals; D003214:Conditioning, Classical / Q000187:drug effects; D006614:Hindlimb / Q000502:physiology; D008297:Male; D008543:Melanins / Q000494:pharmacology*; D009048:Motor Skills / Q000187:drug effects*; D009068:Movement / Q000187:drug effects*; D010243:Paralysis / Q000503:physiopathology; D004856:Postural Balance / Q000187:drug effects*; D011187:Posture; D011597:Psychomotor Performance / Q000187:drug effects; D051381:Rats; D020127:Recovery of Function / Q000187:drug effects; D013378:Substantia Nigra / Q000293:injuries / Q000502:physiology*; D014741:Video Recording
chemical_list: D008543:Melanins