title: Recovery pattern of non-protein respiratory quotient and non-esterified fatty acids after liver resection.
abstract: OBJECTIVE
  Perioperative nutritional care is important to maintain preoperative and postoperative nutritional status. However, few reports have investigated energy metabolism after hepatectomy. The aim of this study was to determine differences in energy metabolism, blood biochemistry, and nutritional status before and after liver resection in patients with hepatocellular carcinoma (HCC) and healthy living donors for liver transplantation.
  
  
  METHODS
  Eighteen hospitalized patients with HCC group and 13 living donors for liver transplantation (donor group) were enrolled in this study. The donor group was divided into two groups on the basis of age; Y-donor group (age < 40 y, n = 7), and O-donor group (age ≥ 40 y, n = 6). Energy metabolism was measured by indirect calorimetry at preoperative day and postoperative day (POD) 7 and 14, and blood biochemistry was also examined.
  
  
  RESULTS
  Recovery of non-protein respiratory quotient (npRQ) and blood biochemical data such as total bilirubin, aspartate aminotransferase and alanine aminotransferase levels were observed in Y-donor group on POD 14. However, although biochemical data improved in the HCC and O-donor group, npRQ remained unchanged on POD 14.
  
  
  CONCLUSIONS
  Improvement of npRQ took longer than blood biochemical data in patients with HCC and older donors. Because the recovery of npRQ is associated with donor age, careful nutritional management may be required for a longer time depending on the pathophysiological condition of each patient after hepatectomy.
authors: Departments of Clinical Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.
authors: Kohei
authors: K
authors: Sugihara
authors: Departments of Clinical Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan. Electronic address: yamanaka@nutr.med.tokushima-u.ac.jp.
authors: Hisami
authors: H
authors: Yamanaka-Okumura
authors: Departments of Clinical Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.
authors: Arisa
authors: A
authors: Teramoto
authors: Departments of Clinical Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.
authors: Eri
authors: E
authors: Urano
authors: Department of Statistics and Computer Science, College of Nursing Art and Science, University of Hyogo, Hyogo, Japan.
authors: Takafumi
authors: T
authors: Katayama
authors: Departments of Digestive and Pediatric Surgery, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.
authors: Hiroki
authors: H
authors: Mori
authors: Departments of Digestive and Pediatric Surgery, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.
authors: Tohru
authors: T
authors: Utsunomiya
authors: Departments of Digestive and Pediatric Surgery, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.
authors: Mitsuo
authors: M
authors: Shimada
authors: Departments of Clinical Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.
authors: Eiji
authors: E
authors: Takeda
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D002153:Calorimetry, Indirect; D006528:Carcinoma, Hepatocellular / Q000601:surgery*; D004734:Energy Metabolism; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D005260:Female; D006498:Hepatectomy; D006760:Hospitalization; D006801:Humans; D008099:Liver / Q000601:surgery*; D008113:Liver Neoplasms / Q000601:surgery; D016031:Liver Transplantation; D019520:Living Donors / Q000145:classification; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D011182:Postoperative Care; D011184:Postoperative Period; D055815:Young Adult
chemical_list: D005230:Fatty Acids, Nonesterified; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D001663:Bilirubin
keywords: Hepatectomy; Late evening snack; Non-esterified fatty acids; Non-protein respiratory quotient; Nutritional management