title: The current state of imaging pediatric hemoglobinopathies.
abstract: The hemoglobinopathies are a group of genetic disorders with a broad spectrum of clinical manifestations and radiologic findings. The imaging of pediatric hemoglobinopathies, which is influenced by concomitant hemosiderosis and the sequela of chelation therapy, has evolved over the years along with ever-improving technology. This article reviews and illustrates the most common radiographic and cross-sectional imaging findings of the 2 best known and clinically relevant hemoglobinopathies in pediatric patients, sickle cell disease and β-thalassemia.
authors: Department of Medical Imaging, Nemours Children's Hospital, Orlando, FL.
authors: David
authors: D
authors: Dinan
authors: Department of Medical Imaging, Nemours Children's Hospital, Orlando, FL. Electronic address: monica.epelman@nemours.org.
authors: Monica
authors: M
authors: Epelman
authors: Department of Medical Imaging, Nemours Children's Hospital, Orlando, FL.
authors: Carolina V
authors: CV
authors: Guimaraes
authors: Nemours Children's Hospital, Orlando, FL.
authors: Lane F
authors: LF
authors: Donnelly
authors: Nemours Center for Cancer and Blood Disorders, Nemours Children's Hospital, Orlando, FL.
authors: Ramamoorthy
authors: R
authors: Nagasubramanian
authors: Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, PA.
authors: Nancy A
authors: NA
authors: Chauvin
mesh_terms: D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014463:Ultrasonography / Q000379:methods*; D017086:beta-Thalassemia / Q000175:diagnosis*