title: Gemcitabine for the treatment of classic Kaposi's Sarcoma: a case series.
abstract: Radiation-refractory and progressive Kaposi's sarcoma remains a challenge for the oncologist. Systemic chemotherapy has improved, but results are poor. Gemcitabine is largely employed in oncology for its high therapeutic rates. We report four cases of patients with radiation-refractory and progressive classic Kaposi's sarcoma, two of whom were pre-treated with chemotherapy and then underwent treatment with gemcitabine. All patients had an objective response with long progression-free survival. Gemcitabine seems to be very effective and safe in the treatment of classic Kaposi's sarcoma.
authors: Oncologia Medica 1, Ospedale Busonera, via Gattamelata 64, 35128 Padova, Italy. Mobile: +39 3479775504, fable.zustovich@ioveneto.it.
authors: Fable
authors: F
authors: Zustovich
authors: Alessandra
authors: A
authors: Ferro
authors: Silvia
authors: S
authors: Toso
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D018572:Disease-Free Survival; D006801:Humans; D008297:Male; D008875:Middle Aged; D012514:Sarcoma, Kaposi / Q000188:drug therapy*; D016896:Treatment Outcome; D000093542:Gemcitabine
chemical_list: D000970:Antineoplastic Agents; D003841:Deoxycytidine; D000093542:Gemcitabine
keywords: Kaposi's sarcoma; case series; chemotherapy; gemcitabine