title: First-in-class guanylate cyclase stimulator approved for PAH.
authors: Malini
authors: M
authors: Guha
mesh_terms: D017277:Drug Approval; D004789:Enzyme Activation / Q000187:drug effects; D065627:Familial Primary Pulmonary Hypertension; D005858:Germany; D006162:Guanylate Cyclase / Q000187:drug effects*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D011655:Pulmonary Embolism / Q000188:drug therapy*; D011720:Pyrazoles / Q000627:therapeutic use*; D011743:Pyrimidines / Q000627:therapeutic use*; D016896:Treatment Outcome; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D011720:Pyrazoles; D011743:Pyrimidines; D006162:Guanylate Cyclase; C542595:riociguat