title: Prostate stem cell antigen - novel biomarker and therapeutic target?
abstract: Prostate stem cell antigen gene was originally identified through an analysis of genes upregulated in the human prostate cancer LAPC-4 xenograft model. PSCA was named inaccurately since it is not a marker for a stem cell population nor is it exclusively expressed in the prostate. The function of PSCA in normal cellular processes or carcinogenesis is currently unknown.
authors: Department of Urology, Hospital Prof. Doutor Fernando Fonseca and Hospital CUF Descobertas, Lisbon, Portugal.
authors: Pedro
authors: P
authors: Bargão Santos
authors: Hitendra Rh
authors: HR
authors: Patel
mesh_terms: D000818:Animals; D000951:Antigens, Neoplasm / Q000235:genetics*; D014408:Biomarkers, Tumor / Q000378:metabolism*; D058851:GPI-Linked Proteins / Q000235:genetics; D006801:Humans; D008297:Male; D058990:Molecular Targeted Therapy; D009363:Neoplasm Proteins / Q000235:genetics*; D011471:Prostatic Neoplasms / Q000235:genetics* / Q000473:pathology; D023041:Xenograft Model Antitumor Assays
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D058851:GPI-Linked Proteins; D009363:Neoplasm Proteins; C110843:PSCA protein, human