title: A metal-free tandem C-C/C-O bond formation approach to diversely functionalized tetrasubstituted furans.
abstract: A novel and efficient method for the synthesis of diversely functionalized furans is developed via DBU-mediated tandem Michael addition/5-exo-dig-cycloisomerization of enynes and keto-methylenes. This [3 + 2]-annulation is operationally simple under metal-free reaction conditions with 100% atom economy and broad substrate scope.
authors: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad-500007, Andhra Pradesh, India.
authors: Chada
authors: C
authors: Raji Reddy
authors: Motatipally
authors: M
authors: Damoder Reddy
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D008670:Metals / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000480:Alkynes; D005663:Furans; D007659:Ketones; D008670:Metals