title: [Disseminated intravascular coagulopathy in a dog with Angiostrongylus vasorum infection].
abstract: A 2-year-old female spayed Epagneul-Breton dog was presented with ecchymoses, but an undisturbed general condition. Clinical examination additionally revealed petechia and a haematoma. Travel history included Italy and Denmark. Laboratory abnormalities were moderate thrombocytopenia, prolonged PT, aPTT and TT, and elevated d-dimers. Initial therapy consisted of plasma transfusions, fluids, doxycycline and famotidine administration. Babesiosis, ehrlichiosis, leishmaniosis, dirofilariosis or anaplasmosis could not be confirmed. Abdominal ultrasound was unremarkable, while thoracic radiographs showed a bronchointerstitial pattern. Faecal samples collected over 3 days were positive for Angiostrongylus vasorum after examination using the Baermann lungworm test. The A. vasorum infection was successfully treated with fenbendazole, whereupon thrombocytopenia and prolonged coagulation times were resolved. In regions of low prevalence, an infection with A. vasorum should also be considered as a differential diagnosis in dogs with coagulation abnormalities. Respiratory signs can be absent with this disease. The patient may have acquired the infection abroad or in Germany.
authors: Dr. Astrid Wehner, Dipl. ECVIM-CA Innere Medizin, Medizinische Kleintierklinik der Ludwig-Maximilians-Universität München, Veterinärstraße 13, 80539 München, E-Mail: astrid.wehner@med.vetmed.uni-muenchen.de.
authors: B D
authors: BD
authors: Kruse
authors: K
authors: K
authors: Hartmann
authors: A
authors: A
authors: Groth
authors: B
authors: B
authors: Schulz
authors: A
authors: A
authors: Wehner
mesh_terms: D000801:Angiostrongylus / Q000302:isolation & purification*; D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D004283:Dog Diseases / Q000097:blood* / Q000188:drug therapy / Q000469:parasitology*; D004285:Dogs; D005243:Feces / Q000469:parasitology; D005260:Female; D005273:Fenbendazole / Q000627:therapeutic use; D017206:Strongylida Infections / Q000097:blood / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*
chemical_list: D000969:Antinematodal Agents; D005273:Fenbendazole
keywords: Lung worm; coagulation disorder; parasite; respiratory infection