title: [Progress in researches on the sperm centrosome].
abstract: In humans and most mammals, the sperm centrosome is primarily responsible for nucleating and organizing the sperm astar, which pushes the sperm head toward the oocyte center and guides the migration of the female pronucleus, completing the fertilization process. There are about 200 kinds of protein in the human sperm centrosome. Currently, most of the researches focus on the centrin protein. Further studies on the functions of different human sperm centrosomal proteins may contribute to the understanding of the causes of the failures in assisted reproductive technology (ART). And in ART, morphological observation of the sperm neck integrity is the only way for primary evaluation of the function of the sperm centrosome.
authors: Center of Reproductive Medicine, Jinjiang Maternity and Child Health Hospital, Chengdu, Sichuan 610051, China. mengxq312@tom.com
authors: Xiang-Qin
authors: XQ
authors: Meng
authors: Center of Reproductive Medicine, Jinjiang Maternity and Child Health Hospital, Chengdu, Sichuan 610051, China.
authors: Yong-Mei
authors: YM
authors: Zeng
authors: Center of Reproductive Medicine, Jinjiang Maternity and Child Health Hospital, Chengdu, Sichuan 610051, China.
authors: Jun
authors: J
authors: Huang
authors: Center of Reproductive Medicine, Jinjiang Maternity and Child Health Hospital, Chengdu, Sichuan 610051, China.
authors: Ying
authors: Y
authors: Zhong
mesh_terms: D002135:Calcium-Binding Proteins / Q000502:physiology; D018385:Centrosome / Q000502:physiology*; D002868:Chromosomal Proteins, Non-Histone / Q000502:physiology; D006801:Humans; D008297:Male; D027724:Reproductive Techniques, Assisted; D013094:Spermatozoa / Q000166:cytology*
chemical_list: D002135:Calcium-Binding Proteins; D002868:Chromosomal Proteins, Non-Histone; C056608:caltractin