title: Rubella virus genotype 1G and echovirus 9 as etiologic agents of exanthematous diseases in Brazil: insights from phylogenetic analysis.
abstract: The aim of the present study was to identify the rubella virus (RV) and enterovirus (EV) genotypes detected during the Epidemiological Surveillance on Exanthematic Febrile Diseases (VIGIFEX) study and to perform phylogenetic analysis. Ten RV- and four EV-positive oropharyngeal samples isolated from cell culture were subjected to RT-PCR and sequencing. Genotype 1G and echovirus 9 (E-9) was identified in RV- and EV-positive samples, respectively. The RV 1G genotype has been persisting in Brazil since 2000-2001. No evidence of E-9 being involved in exanthematic illness in Brazil has been reported previously. Differential laboratory diagnosis is essential for management of rash and fever disease.
authors: Núcleo de Doenças Respiratórias, Instituto Adolfo Lutz, Av. Dr. Arnaldo, 355, 01246-902, São Paulo, SP, Brazil, figueiredocris@uol.com.br.
authors: Cristina Adelaide
authors: CA
authors: Figueiredo
authors: Adriana
authors: A
authors: Luchs
authors: Denise Hage
authors: DH
authors: Russo
authors: Rita
authors: R
authors: de Cassia Compagnoli Carmona
authors: Ana Maria Sardinha
authors: AM
authors: Afonso
authors: Maria Isabel
authors: MI
authors: de Oliveira
authors: Suely Pires
authors: SP
authors: Curti
authors: José Cassio
authors: JC
authors: de Moraes
authors: Cristiana M
authors: CM
authors: Toscano
authors: Flavia Helena
authors: FH
authors: Ciccone
authors: Maria do Carmo Sampaio Tavares
authors: Mdo C
authors: Timenetsky
mesh_terms: D001938:Brazil / Q000453:epidemiology; D016000:Cluster Analysis; D004459:Echovirus 9 / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D004457:Echovirus Infections / Q000453:epidemiology* / Q000821:virology; D005838:Genotype; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D009960:Oropharynx / Q000821:virology; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012409:Rubella / Q000453:epidemiology* / Q000821:virology; D012412:Rubella virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D017422:Sequence Analysis, DNA
chemical_list: D012367:RNA, Viral