title: Seroprevalence of parvovirus B19 IgG and IgM antibodies among pregnant women in Oyo State, Nigeria.
abstract: BACKGROUND
  Human parvovirus B19 causes a wide range of complications in pregnant women including abortion, severe fetal anemia, non-immune hydrops fetalis, and even intrauterine fetal death. However, there is a dearth of information on the prevalence of the virus among pregnant women in southwestern Nigeria.
  
  
  METHODS
  Blood samples were collected from 231 pregnant women and screened for antibodies to human parvovirus B19 IgM and IgG using an enzyme immunosorbent assay kits.
  
  
  RESULTS
  Of the 231 women, 31 were in their first trimester, 146 were in their second trimester, and 54 were in their third trimester. Forty-five (20%) were positive for parvovirus B19 IgG antibodies, 10 (4%) were positive for parvovirus B19 IgM antibodies, and 176 (76%) had no detectable parvovirus B19 antibodies. Twenty-eight (19%) of the 146 pregnant women in their second trimester were positive for parvovirus B19 IgG antibody while three (2%) of the 146 were positive for parvovirus B19 IgM antibody.
  
  
  CONCLUSIONS
  It is evident that there is a high prevalence of human parvovirus B19 among pregnant women in south-western Nigeria. This suggests that there is an active transmission of the virus in the community; it is therefore necessary to conduct more studies on the virus in pregnant women in Nigeria to ascertain its effect on the fetus.
authors: Ladoke Akintola University of Technology, Ogbomoso, Nigeria. kola_abiodun777@yahoo.com.
authors: Iyanda
authors: I
authors: Abiodun
authors: Oluyinka Oladele
authors: OO
authors: Opaleye
authors: Olusola
authors: O
authors: Ojurongbe
authors: Ademola Hezekiah
authors: AH
authors: Fagbami
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood*; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D010322:Parvoviridae Infections / Q000453:epidemiology*; D016732:Parvovirus B19, Human / Q000276:immunology*; D011247:Pregnancy; D037841:Pregnant People; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M