title: [Treatment of drug-resistant depression].
abstract: Depression is drug-resistant, if the severity of the symptoms has not decreased to half of the starting situation, despite appropriately conducted treatment with two antidepressants belonging to two different pharmacological categories. The incidence of drug-resistant depression in Finland is approximately 1%, and it is being treated too passively, whereby the number of disability pensions is rising. Current treatments include combinations of antidepressants, additional drugs for depression, psychotherapy, electrotherapy and serial magnetic stimulation. Ketamine infusions are also an effective, yet still experimental form of treatment.
authors: Yleissairaalapsykiatrian osasto PT715, TYKS:n aikuispsykiatrian erityispalveluyksikkö.
authors: Tero
authors: T
authors: Taiminen
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D003863:Depression / Q000188:drug therapy / Q000628:therapy*; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D004599:Electric Stimulation Therapy; D018691:Excitatory Amino Acid Antagonists / Q000627:therapeutic use; D006801:Humans; D007649:Ketamine / Q000627:therapeutic use; D055909:Magnetic Field Therapy; D011613:Psychotherapy
chemical_list: D000928:Antidepressive Agents; D018691:Excitatory Amino Acid Antagonists; D007649:Ketamine