title: Copper-catalyzed intermolecular cyanotrifluoromethylation of alkenes.
abstract: A novel and highly practical reaction for the copper-catalyzed intermolecular cyanotrifluoromethylation of alkenes is presented here. This methodology provides a general and straightforward way to synthesize a variety of useful CF3-containing nitriles, which can be used for further preparation of pharmaceutically and agrochemically important compounds in synthetic organic chemistry.
authors: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou 730000, P.R. China.
authors: Yu-Tao
authors: YT
authors: He
authors: Lian-Hua
authors: LH
authors: Li
authors: Yan-Fang
authors: YF
authors: Yang
authors: Zhao-Zhao
authors: ZZ
authors: Zhou
authors: Hui-Liang
authors: HL
authors: Hua
authors: Xue-Yuan
authors: XY
authors: Liu
authors: Yong-Min
authors: YM
authors: Liang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D008745:Methylation; D015394:Molecular Structure; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry*
chemical_list: D000475:Alkenes; D006845:Hydrocarbons, Fluorinated; D009570:Nitriles; D009942:Organometallic Compounds; D003300:Copper