title: Recurrent Central Serous Chorioretinopathy with Dexamethasone Eye Drop used Nasally for Rhinitis.
abstract: Central serous chorioretinopathy (CSC) is characterized by serous retinal detachment at the posterior pole. Several factors have been implicated in the pathogenesis, and endogenous or exogenous corticosteroids are thought to play a major role. Here we present a case of a 35-year-old male with complaints of a dark circle in front of his right eye. Fundus examination, optical coherence tomography and fundus fluorescein angiography were performed. The patient was diagnosed with CSC. CSC resolved completely within seven weeks. Four weeks later the CSC recurred and spontaneously resolved over eight weeks. Overall, the patient had three additional recurrences of CSC in the same eye over the next year. A detailed history taking revealed the patient was using 0.1% dexamethasone eye drops nasally for recurrent rhinitis for few days prior to each episode of CSC. This indicates the strong correlation between steroids given by any route and the pathogenesis of CSC.
authors: Department of Ophthalmology, Sarojini Naidu Medical College, Agra, Uttar Pradesh, India.
authors: Gunjan
authors: G
authors: Prakash
authors: Jain
authors: J
authors: Shephali
authors: Nath
authors: N
authors: Tirupati
authors: Pandey D
authors: PD
authors: Ji
mesh_terms: D000281:Administration, Intranasal; D000328:Adult; D056833:Central Serous Chorioretinopathy / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D003907:Dexamethasone / Q000008:administration & dosage / Q000009:adverse effects*; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009883:Ophthalmic Solutions; D012008:Recurrence; D012220:Rhinitis / Q000188:drug therapy*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology
chemical_list: D005938:Glucocorticoids; D009883:Ophthalmic Solutions; D003907:Dexamethasone
keywords: Central Serous Chorioretinopathy; Cortisol; Dexamethasone; Nasal Drop