title: Extramedullary plasmacytoma of the tongue base: a rare presentation of head and neck plasmacytoma.
abstract: BACKGROUND
  Special entities like solitary bone plasmocytoma (SBP) or extramedullary plasmacytoma (EMP) can be found in a less than 5% of patients with plasma cell disorders. EMP of the tongue represents very rare localization of the head and neck plasmacytoma.
  
  
  METHODS
  We report a case of 78-years-old woman who developed EMP of the tongue base detected by the magnetic resonance imaging (MRI) of the head and neck region. Immunohistochemical profile of the tumor tissue biopsy (CD38, IgG, kappa positivity) indicated diagnosis of EMP. The diagnosis was established with additional staging which confirmed the absence of other manifestation of the disease. The patient was treated with 40 Gy of radiotherapy in 20 doses resulting in the achievement of the complete remission of the disease. This case was discussed with the reference to the literature.
  
  
  CONCLUSIONS
  EMP of the tongue base is a very rare entity of plasma cell dyscrasias. Appropriate irradiation results in the achievement of a long-term remission and a potential cure of the disease.
authors: Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia. jbila@yubc.net
authors: Jelena
authors: J
authors: Bila
authors: Bosko
authors: B
authors: Andjelić
authors: Jelena
authors: J
authors: Bodrozić
authors: Ljubomir
authors: L
authors: Jaković
authors: Maja Perunicić
authors: MP
authors: Jovanović
authors: Ana
authors: A
authors: Vidović
authors: Milena
authors: M
authors: Todorović
authors: Biljana
authors: B
authors: Mihaljević
mesh_terms: D000368:Aged; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000503:physiopathology / Q000532:radiotherapy; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D009367:Neoplasm Staging; D010954:Plasmacytoma / Q000473:pathology / Q000503:physiopathology / Q000532:radiotherapy; D011878:Radiotherapy / Q000379:methods*; D012074:Remission Induction; D014059:Tongue / Q000473:pathology*