title: A study on hypoglycaemic health care function of Stigma maydis polysaccharides.
abstract: The objective of this paper was to study the therapeutic effect of Stigma maydis polysaccharides in diabetic mice. Mouse models of types 1 and 2 diabetes were established. The body weight, food intake, water intake as well as blood sugar level and glucose tolerance of mice were measured. Stigma maydis polysaccharides can improve the symptoms of weight loss and polydipsia in diabetic mice, and had an obvious antagonistic effect on alloxan-induced hyperglycaemia. The glucose tolerance test also showed that the Stigma maydis polysaccharides had very good effects on suppression and prevention of acute hyperglycaemia. Stigma maydis polysaccharides have some improvement effect on alloxan-induced types 1 and 2 diabetes.
authors: Department of Endocrinology, The 309th Hospital of Chinese People's Liberation Army, Beijing 100091, China.
authors: Yan
authors: Y
authors: Zhang
authors: Jing-bo
authors: JB
authors: Wang
authors: Liang
authors: L
authors: Wang
authors: Li-ying
authors: LY
authors: Zhen
authors: Quang-qing
authors: QQ
authors: Zhu
authors: Xiao-wen
authors: XW
authors: Chen
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy; D004195:Disease Models, Animal; D035264:Flowers / Q000737:chemistry; D005951:Glucose Tolerance Test; D006943:Hyperglycemia / Q000097:blood / Q000188:drug therapy*; D007004:Hypoglycemic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D059606:Polydipsia / Q000188:drug therapy / Q000209:etiology; D011134:Polysaccharides / Q000494:pharmacology / Q000627:therapeutic use*; D015431:Weight Loss / Q000187:drug effects; D003313:Zea mays / Q000737:chemistry*
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D011134:Polysaccharides
keywords: Stigma maydis polysaccharides; hypoglycaemia; ultrasonic extraction