title: Chemotherapy-induced acral erythema with involvement of the face and neck: A case report.
abstract: Chemotherapy-induced acral erythema (CIAE) is a cutaneous response to diverse chemotherapeutic drug administration. These drugs cause symmetrical and painful erythema of palmoplantar surfaces. Bulla formation, desquamation, and subsequent reepithelialization may occur. Commonly, the lesions slowly resolve over 7-15 days, through desquamation, followed by regeneration of the skin. Here, we described a case of CIAE, with involvement of face and neck in a patient treated for breast cancer using a number of chemotherapeutic agents. Face involvement in CIAE has not been previously reported in the literature.
authors: Department of Dermatology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey drhaticeuce@gmail.com.
authors: Hatice Uce
authors: HU
authors: Ozkol
authors: Department of Dermatology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
authors: Omer
authors: O
authors: Calka
authors: Department of Pathology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
authors: Gulay
authors: G
authors: Bulut
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy; D003520:Cyclophosphamide / Q000009:adverse effects / Q000627:therapeutic use; D000077143:Docetaxel; D004305:Dose-Response Relationship, Drug; D015251:Epirubicin / Q000009:adverse effects / Q000627:therapeutic use; D005145:Face / Q000473:pathology*; D005260:Female; D060831:Hand-Foot Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D009333:Neck / Q000473:pathology*; D011736:Pyridoxine / Q000494:pharmacology; D012867:Skin / Q000187:drug effects / Q000473:pathology; D043823:Taxoids / Q000009:adverse effects / Q000627:therapeutic use; D000068878:Trastuzumab / Q000009:adverse effects / Q000627:therapeutic use; D014803:Vitamin B Complex / Q000494:pharmacology; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents; D043823:Taxoids; D014803:Vitamin B Complex; D000077143:Docetaxel; D015251:Epirubicin; D003520:Cyclophosphamide; D011736:Pyridoxine; D000068878:Trastuzumab
keywords: Acral erythema; chemotherapy; face and neck