title: [Pharmacological characterization of metabotropic glutamate-receptor 1 antagonist for the treatment of schizophrenia].
authors: Shunsuke
authors: S
authors: Maehara
mesh_terms: D000818:Animals; D001562:Benzimidazoles / Q000378:metabolism / Q000494:pharmacology; D055808:Drug Discovery; D006801:Humans; D054833:Isoindoles / Q000378:metabolism / Q000494:pharmacology*; D051379:Mice; D058990:Molecular Targeted Therapy; D009281:Naphthalenes / Q000378:metabolism / Q000494:pharmacology; D011485:Protein Binding; D051381:Rats; D018094:Receptors, Metabotropic Glutamate / Q000037:antagonists & inhibitors* / Q000378:metabolism / Q000502:physiology*; D012559:Schizophrenia / Q000188:drug therapy* / Q000235:genetics*; D013844:Thiazoles / Q000378:metabolism / Q000494:pharmacology; D014230:Triazoles / Q000378:metabolism / Q000494:pharmacology*
chemical_list: C542317:2-cyclopropyl-5-(1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl)-2,3-dihydro-1H-isoindol-1-one; C521338:4-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3,-triazol-4-yl)-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide; C505455:6-amino-N-cyclohexyl-N,3-dimethylthiazolo(3,2-a)benzimidazole-2-carboxamide; C425484:BAY36-7620; D001562:Benzimidazoles; D054833:Isoindoles; D009281:Naphthalenes; D018094:Receptors, Metabotropic Glutamate; D013844:Thiazoles; D014230:Triazoles; C104077:metabotropic glutamate receptor type 1