title: Rapid progression of neuromuscular disorder related cardiomyopathy in a young patient.
abstract: An 11-year and 3-month-old boy with a neuromuscular disorder was admitted for dyspnea. Echocardiography revealed severe left ventricular dysfunction with an ejection fraction (EF) of 17%. However, the EF had been 57% when the patient was 10 years and 9 months old. The patient's clinical condition became refractory, and he died on the 155th day of hospitalization. Speckle-tracking analysis was retrospectively performed, which demonstrated that the global radial strain was within the normal range; however, the global longitudinal and circumferential strains were lower -than -normal 10 years and 9 months of age. Adult neuromuscular disorder-related secondary cardiomyopathy generally progresses slowly, although progression depends on the age of onset of cardiomyopathy.
authors: Department of Clinical Laboratory, Kobe University Hospital, Japan.
authors: Mayuko
authors: M
authors: Hayashi
authors: Hidekazu
authors: H
authors: Tanaka
authors: Tetsushi
authors: T
authors: Yamamoto
authors: Tomoko
authors: T
authors: Lee
authors: Hiroyuki
authors: H
authors: Awano
authors: Mariko
authors: M
authors: Yagi
authors: Takamitsu
authors: T
authors: Imanishi
authors: Nobuhide
authors: N
authors: Hayashi
authors: Yasuhiro
authors: Y
authors: Takeshima
authors: Hiroya
authors: H
authors: Kawai
authors: Ken-ichi
authors: K
authors: Hirata
authors: Seiji
authors: S
authors: Kawano
mesh_terms: D009202:Cardiomyopathies / Q000150:complications* / Q000175:diagnosis*; D002648:Child; D018450:Disease Progression; D006801:Humans; D008297:Male; D009468:Neuromuscular Diseases / Q000150:complications* / Q000175:diagnosis*; D013997:Time Factors