title: Incidence and predictive factors of depression among patients with HIV infection in Guadeloupe: 1988-2009.
abstract: A retrospective cohort study was conducted to determine the incidence and the predictive factors of depression in a cohort of 2737 HIV/AIDS-infected patients in Guadeloupe followed for a total of 8402 patient-years. The incidence rate of first observed depression was 2.2 per 100 person-years (95% confidence interval [CI], 1.9-2.6). A single failure Cox proportional hazards model showed that the 1997-2000 inclusion period (hazard ratio [HR] = 1.60; 95% CI = 1.10-2.40;p = 0.01), the 2001-2009 inclusion period (HR = 1.50; 95% CI = 1.02-2.40;p = 0.04), the more advanced CDC stage (HR = 2.30; 95% CI = 1.30-3.10;p = 0.000) and the annual frequency of visits > 10 (HR = 2.30; 95% CI = 1.70-3.30;p = 0.000) were associated with an increased risk of depression. Incidence of depression in this HIV cohort was high and the hazard function showed three peaks of depression (2, 7 and 12 years). Physicians should be vigilant to psychological distress throughout life with HIV.
authors: Service de Pédiatrie, Centre hospitalier de Cayenne «Andrée Rosemon», Cayenne, French Guiana elengafr@yahoo.fr.
authors: Narcisse
authors: N
authors: Elenga
authors: Coordination Régionale VIH (COREVIH) Guadeloupe CHU de Pointe-à-Pitre/Abymes Bâtiment B Ancien Hôpital Ricou 2ème étage, Pointe-à-Pitre, Guadeloupe.
authors: Marie-Thérèse
authors: MT
authors: Georger-Sow
authors: Service des maladies infectieuses, Guadeloupe CHU de Pointe-à-Pitre/Abymes Bâtiment B Ancien Hôpital Ricou 2ème étage, Pointe-à-Pitre, Guadeloupe.
authors: Thierry
authors: T
authors: Messiaen
authors: Service des maladies infectieuses, Guadeloupe CHU de Pointe-à-Pitre/Abymes Bâtiment B Ancien Hôpital Ricou 2ème étage, Pointe-à-Pitre, Guadeloupe.
authors: Isabelle
authors: I
authors: Lamaury
authors: Service des maladies infectieuses, Guadeloupe CHU de Pointe-à-Pitre/Abymes Bâtiment B Ancien Hôpital Ricou 2ème étage, Pointe-à-Pitre, Guadeloupe.
authors: Isabelle
authors: I
authors: Favre
authors: Coordination Régionale VIH (COREVIH) Centre hospitalier de Cayenne «Andrée Rosemon», Cayenne, French Guiana Centre d'Investigation Clinique Epédémiologie Clinique CIC EC Antilles Guyane CIE 802, Centre hospitalier de Cayenne « Andrée Rosemon», Cayenne Cedex, French Guiana.
authors: Mathieu
authors: M
authors: Nacher
authors: Service des maladies infectieuses, Guadeloupe CHU de Pointe-à-Pitre/Abymes Bâtiment B Ancien Hôpital Ricou 2ème étage, Pointe-à-Pitre, Guadeloupe.
authors: Gilles
authors: G
authors: Beaucaire
mesh_terms: D000328:Adult; D015331:Cohort Studies; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D019430:Guadeloupe / Q000453:epidemiology; D015658:HIV Infections / Q000453:epidemiology / Q000523:psychology*; D006801:Humans; D015994:Incidence; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000453:epidemiology / Q000523:psychology*; D011237:Predictive Value of Tests; D016016:Proportional Hazards Models; D011569:Psychiatric Status Rating Scales; D012189:Retrospective Studies; D012307:Risk Factors
keywords: AIDS; Guadeloupe; HIV; depression; incidence; mood disorders; predictive factors