title: Incidence of metabolic syndrome and relative importance of five components as a predictor of metabolic syndrome: 5-year follow-up study in Korea.
abstract: The aim of this study was to describe the incidence of metabolic syndrome and to identify five components as metabolic syndrome predictors. The final study included 1,095 subjects enrolled in a rural part of Daegu Metropolitan City, Korea for a cohort study in 2003. Of these, 762 (69.6%) subjects had participated in the repeat survey. During the five-year follow-up, incidence density was significantly higher for women than for men (men, 30.0/1,000 person-years; women, 46.4/1,000 person-years). In both men and women, incidence of metabolic syndrome showed a significant increase with increasing number of metabolic syndrome components at baseline. Compared with individuals presenting none of components at baseline, relative risks were increased 1.22 (men; 95% CI, 0.43-3.51), 2.21 (women; 95% CI, 0.98-4.97) times more for individuals with one component of metabolic syndrome and 5.30 (men; 95% CI, 2.31-12.13), 5.53 (women; 95% CI, 2.78-11.01) times more for those who had two components. In multivariate analysis, the most powerful risk factor for metabolic syndrome was abdominal obesity in men and low HDL-cholesterol in women (adjusted relative risk, 3.28, 2.53, respectively). Consequently, finding a high risk group for metabolic syndrome according to gender and prevention of metabolic syndrome through lifestyle modification are essential.
authors: Department of Preventive Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
authors: Jun Hyun
authors: JH
authors: Hwang
authors: Sin
authors: S
authors: Kam
authors: Ji-yeon
authors: JY
authors: Shin
authors: Jong-Yeon
authors: JY
authors: Kim
authors: Kyung-Eun
authors: KE
authors: Lee
authors: Gi-Hong
authors: GH
authors: Kwon
authors: Byung-Yeol
authors: BY
authors: Chun
authors: Shung Chull
authors: SC
authors: Chae
authors: Dong Heon
authors: DH
authors: Yang
authors: Hun Sik
authors: HS
authors: Park
authors: Tae-Yoon
authors: TY
authors: Hwang
mesh_terms: D000328:Adult; D000368:Aged; D008076:Cholesterol, HDL / Q000097:blood; D015331:Cohort Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000150:complications; D015228:Hypertriglyceridemia / Q000150:complications; D015994:Incidence; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology*; D008875:Middle Aged; D015999:Multivariate Analysis; D056128:Obesity, Abdominal / Q000150:complications; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors
chemical_list: D008076:Cholesterol, HDL
keywords: Cohort Studies; Incidence; Metabolic Syndrome; Risk Factors