title: Oil-water biphasic parallel flow for the precise patterning of metals and cells.
abstract: Fluidic patterning is a convenient and versatile tool for the patterning of materials, cells and microstructures on surface and in microchannels. However, its performance is usually limited by transverse diffusion between fluid streams. It would blur the boundary and deteriorate the precision of patterns. In this paper, we adopted geometric confinement to generate biphasic parallel flow that is constituted of oil and water. Since there is minimum transverse diffusion in biphasic parallel flow, the performance of fluid patterning is expected to be improved. The results show that the metal (Silver and Chromium) patterns have distinct boundary and well-controlled geometry in comparison with that by conventional laminar flow patterning. Furthermore, the high biocompatibility of oil phase (perfluorodecalin, PFD) enables the precise patterning of viable bacteria inside microchannels. Our work demonstrated a new route of using biphasic parallel flow to patterning, which would serve wide applications in prototyping and research settings.
authors: Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, People's Republic of China.
authors: Xuan
authors: X
authors: Mu
authors: Qionglin
authors: Q
authors: Liang
authors: Jun
authors: J
authors: Zhou
authors: Kangning
authors: K
authors: Ren
authors: Ping
authors: P
authors: Hu
authors: Yiming
authors: Y
authors: Wang
authors: Zhi
authors: Z
authors: Zheng
authors: Guoan
authors: G
authors: Luo
mesh_terms: D002857:Chromium / Q000737:chemistry*; D004926:Escherichia coli / Q000737:chemistry*; D005466:Fluorocarbons / Q000737:chemistry*; D009821:Oils / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*
chemical_list: D005466:Fluorocarbons; D009821:Oils; D002857:Chromium; D012834:Silver; C008805:perfluorodecalin