title: Adrenal and pituitary incidentalomas in a case of Cushing's syndrome.
abstract: Cushing's syndrome is a pathological condition where surgery may be lifesaving. The proper diagnosis depends upon the hormonal pattern of the patient, various dynamic tests and imagistic investigations. We report a case of a patient with Cushing's syndrome, with bilateral adrenal tumors and a pituitary microadenoma. She presented increased levels of basal cortisol, unsuppressed during a low and a high dose Dexamethasone test. She underwent right laparoscopic adrenalectomy and developed acute adrenal insufficiency. Two years after the intervention, she still requires adrenal substitution therapy. Acute adrenal crisis is a serious complication of adrenal surgery, with high mortality if unrecognized.
authors: C
authors: C
authors: Poiană
authors: C
authors: C
authors: Chiriţă
authors: M
authors: M
authors: Carşote
authors: D
authors: D
authors: Hortopan
authors: D
authors: D
authors: Ioachim
authors: C M
authors: CM
authors: Corneci
authors: B
authors: B
authors: Stănescu
mesh_terms: D000236:Adenoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000309:Adrenal Insufficiency / Q000188:drug therapy / Q000209:etiology*; D000315:Adrenalectomy / Q000009:adverse effects*; D000328:Adult; D015992:Body Mass Index; D003480:Cushing Syndrome / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000150:complications; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D033162:Incidental Findings; D010535:Laparoscopy; D008687:Metformin / Q000627:therapeutic use; D009765:Obesity / Q000150:complications; D010911:Pituitary Neoplasms / Q000150:complications / Q000175:diagnosis*; D012307:Risk Factors; D016896:Treatment Outcome; D016312:Treatment Refusal
chemical_list: D005938:Glucocorticoids; D007004:Hypoglycemic Agents; D008687:Metformin