title: Cardiac involvement and its complications about three cases of severe scorpion envenomation.
abstract: For several decades, Morocco is confronted to medico-social problem of scorpion stings and envenomations. In 2009, epidemiological data established by the Poison Control Center recorded 29,816 stung patients, with an incidence of 1.1‰ and a fatality rate of 0.18%. The neurotoxins from scorpion venom are potent activators of the autonomic nervous system resulting a physiopathological disorder of vital systems. The most serious clinical manifestations are neurotoxic effects, pulmonary edema and cardiovascular distress. This present work reports the cases of three children (4 years and 6 months, 8 months and 15 days, 4 years), hospitalized in intensive care for an envenomation by Androctonus mauritanicus (the most fatal scorpion specie). The children presented cardiac dysfunction where pulmonary edema and state of shock were complications resultants. Two cases survived after supportive and symptomatic treatment based on dobutamine as primordial treatment in cardiovascular and pulmonary correction and other drugs. The third case died. The objective of this work was to detect the limit of the effectiveness of symptomatic treatment during a severe scorpion envenomation.
authors: Medical Intensive Care Unit, Hospital Mohammed V, El Jadida, Morocco; Laboratory of Biochemistry and Neuroscience, Faculty of Science and Technology, University Hassan 1, 26000 Settat, Morocco.
authors: B
authors: B
authors: Aboumaâd
authors: Medical Intensive Care Unit, Hospital Mohammed V, El Jadida, Morocco.
authors: A
authors: A
authors: Tiger
authors: National School of Public Health, Rabat, Morocco.
authors: A
authors: A
authors: Khattabi
authors: Poison Contol and Pharmacovigilance Center of Morocco, Rabat, Morocco.
authors: R
authors: R
authors: Soulaymani
authors: Medical Intensive Care Unit, Hospital Mohammed V, El Jadida, Morocco.
authors: M
authors: M
authors: Lahssaini
authors: Medical Intensive Care Unit, Hospital Mohammed V, El Jadida, Morocco.
authors: S M
authors: SM
authors: Benhassain
authors: Laboratory of Biochemistry and Neuroscience, Faculty of Science and Technology, University Hassan 1, 26000 Settat, Morocco. Electronic address: naima.iba@gmail.com.
authors: N
authors: N
authors: Iba
mesh_terms: D000818:Animals; D002318:Cardiovascular Diseases / Q000139:chemically induced* / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology; D002675:Child, Preschool; D004280:Dobutamine / Q000627:therapeutic use; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D009018:Morocco; D011654:Pulmonary Edema / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*; D065008:Scorpion Stings / Q000503:physiopathology*; D012604:Scorpion Venoms / Q000506:poisoning*; D012605:Scorpions; D012769:Shock / Q000209:etiology / Q000503:physiopathology*
chemical_list: D012604:Scorpion Venoms; D004280:Dobutamine
keywords: Cardiac dysfunction; Pulmonary edema; Scorpion envenomation; Symptomatic treatment