title: [Prognostic value of uteroplacental circulation impairment in 1st trimester of pregnancy in patients with complicated obstetric history].
abstract: One of the urgent problems of modern obstetrics is the early detection of irregularities in the development of the uteroplacental vessels system in patients with severe disorders in the history.
  
  
  OBJECTIVE
  To evaluate the predictive value of re-development of obstetric pathology on the basis of the uterine artery Doppler on 11-14 weeks of pregnancy.
  
  
  METHODS
  410 patients in I trimester of pregnancy were examined with fetal growth restriction, preeclampsia and/or fetal death and/or a history of preterm delivery were. The influence of physical factors and obstetric history on the state of uterine blood flow in the I trimester of pregnancy was studied.
  
  
  RESULTS
  The optimal Doppler indexes was calculated; a high predictive ability of the pulsation index in the uterine arteries with respect to pregnancy complications with early clinical manifestation, severe preeclampsia and combined obstetric complications was detected.
  
  
  CONCLUSIONS
  Our data support the possibility of preclinical diagnosis of obstetrical complications in patients with complicated obstetric history.
authors: G M
authors: GM
authors: Savel'eva
authors: E Iu
authors: EIu
authors: Bugerenko
authors: O B
authors: OB
authors: Panina
mesh_terms: D000328:Adult; D005260:Female; D005317:Fetal Growth Retardation; D006801:Humans; D008875:Middle Aged; D021041:Placental Circulation / Q000502:physiology*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011261:Pregnancy Trimester, First; D011379:Prognosis; D012039:Regional Blood Flow; D016216:Ultrasonography, Prenatal; D055988:Uterine Artery / Q000503:physiopathology* / Q000648:ultrastructure; D014599:Uterus / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000503:physiopathology