title: Efficacy of short-term postoperative perfluoro-n-octane tamponade for pediatric complex retinal detachment.
abstract: OBJECTIVE
  To evaluate the efficacy of perfluoro-n-octane as a postoperative short-term tamponade after vitrectomy in pediatric cases with complex retinal detachment (RD) and proliferative vitreoretinopathy (PVR).
  
  
  METHODS
  Prospective, noncomparative, interventional case series.
  
  
  METHODS
  The medical records of 10 eyes of 9 children (6 boys and 3 girls), whose age ranged from 3 months to 11 years, with a median of 7.5 months, were reviewed. The cause of the PVR was retinopathy of prematurity (7 eyes of 6 patients); familial exudative vitreoretinopathy; or tractional RD associated with congenital optic nerve anomalies,(1) and persistent fetal vasculature. Perfluoro-n-octane was injected into the eyes at the primary surgery in 2 eyes and at the repeat surgeries in 8 eyes. The perfluoro-n-octane was removed after 1 to 4 postoperative weeks. The patients were followed for 5 to 43 months.
  
  
  RESULTS
  At the last examination, the retinas were reattached in 8 eyes (80%). In the other two eyes, a retinal attachment was not obtained. Postoperatively, the best-corrected visual acuity improved from hand motion to 0.1 in 1 eye and could not be measured in the other 9 patients because of their ages. No apparent adverse events related to the use of perfluoro-n-octane were noted.
  
  
  CONCLUSIONS
  Although cautions should be exercised regarding potential mechanical retinal injuries by heavy liquids in the eye, short-term perfluoro-n-octane tamponade was effective in pediatric cases with severe PVR in which retinal reattachment is considered to be difficult with conventional gas or silicone oil tamponade.
authors: Department of Ophthalmology, Naha City Hospital, Okinawa, Japan; Department of Ophthalmology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
authors: Ayako
authors: A
authors: Imaizumi
authors: Department of Ophthalmology, Sakai Hospital Kinki University Faculty of Medicine, Osaka, Japan. Electronic address: kusaka-ns@umin.net.
authors: Shunji
authors: S
authors: Kusaka
authors: Department of Ophthalmology, Naha City Hospital, Okinawa, Japan.
authors: Hiroe
authors: H
authors: Noguchi
authors: Department of Ophthalmology, Sakai Hospital Kinki University Faculty of Medicine, Osaka, Japan.
authors: Yoshikazu
authors: Y
authors: Shimomura
authors: Department of Ophthalmology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
authors: Shoichi
authors: S
authors: Sawaguchi
mesh_terms: D002648:Child; D004322:Drainage; D058450:Endotamponade; D005260:Female; D005466:Fluorocarbons / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D008297:Male; D011182:Postoperative Care; D011446:Prospective Studies; D012160:Retina / Q000503:physiopathology; D012163:Retinal Detachment / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy; D018630:Vitreoretinopathy, Proliferative / Q000503:physiopathology / Q000601:surgery*
chemical_list: D005466:Fluorocarbons; C073608:perfluorooctane