title: Factors predictive of oncological outcome after nephroureterectomy: comparison between laparoscopic and open procedures.
abstract: BACKGROUND
  Although laparoscopic radical nephroureterectomy is the standard treatment for localized upper urinary tract urothelial carcinoma, open radical nephroureterectomy has been reported to have a different rate of intravesical recurrence.
  
  
  METHODS
  Intravesical recurrence-free, progression-free, and overall survival rates among patients undergoing open and laparoscopic radical nephroureterectomy from 2002 to 2013 were analyzed.
  
  
  RESULTS
  Although no single factor predicted intravesical recurrence-free survival, a past history of bladder cancer or grade 3 was related to poorer intravesical recurrence-free survival rate in patients treated with laparoscopic radical nephroureterectomy. Moreover, the novel proposed risk classification based on our data clearly showed better progression-free survival and overall survival, as well as intravesical recurrence-free survival, in patients treated with laparoscopic radical nephroureterectomy.
  
  
  CONCLUSIONS
  The findings reported here may help urologists predict oncological outcomes and to plan follow-up schedules after laparoscopic radical nephroureterectomy.
authors: Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8641, Japan. azuizu2003@yahoo.co.jp.
authors: Kouji
authors: K
authors: Izumi
authors: Shingo
authors: S
authors: Itai
authors: Yoshiko
authors: Y
authors: Takahashi
authors: Rie
authors: R
authors: Takahashi
authors: Aerken
authors: A
authors: Maolake
authors: Mitsuo
authors: M
authors: Ofude
authors: Satoru
authors: S
authors: Ueno
authors: Yoshifumi
authors: Y
authors: Kadono
authors: Yasuhide
authors: Y
authors: Kitagawa
authors: Hiroyuki
authors: H
authors: Konaka
authors: Atsushi
authors: A
authors: Mizokami
authors: Mikio
authors: M
authors: Namiki
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D016019:Survival Analysis; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D013520:Urologic Surgical Procedures / Q000379:methods*
keywords: Laparoscopic nephroureterectomy; upper urinary tract; urothelial carcinoma