title: Blood microvesicles during chronic lymphoproliferative diseases.
abstract: The levels of CD19 (+) and CD20(+) microvesicles were estimated in the blood of patients with B-cell chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma by flow cytometry method. It was found that the number of B cell microvesicles is several times higher in patients than in volunteers. The level of CD20 (+) microvesicles directly correlated with the number of CD20(+) lymphocytes in patients with chronic lymphoproliferative diseases. Extramedullary tumors cells can be a source of CD19 (+) microvesicles.
authors: Research Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences; Research Institute of Molecular Biology and Biophysics, Siberian Division of the Russian Academy of Medical Sciences; Research Institute of Clinical and Experimental Lymphology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk, Russia. pathol@soramn.ru.
authors: N P
authors: NP
authors: Domnikova
authors: T Yu
authors: TY
authors: Dolgikh
authors: E V
authors: EV
authors: Sholenberg
authors: E V
authors: EV
authors: Vorontsova
authors: O B
authors: OB
authors: Goreva
authors: E V
authors: EV
authors: Mel'nikova
authors: E A
authors: EA
authors: Gorbachenko
authors: A Yu
authors: AY
authors: Grishanova
mesh_terms: D000328:Adult; D000368:Aged; D018941:Antigens, CD19 / Q000378:metabolism; D018951:Antigens, CD20 / Q000378:metabolism; D001402:B-Lymphocytes / Q000276:immunology / Q000378:metabolism; D016022:Case-Control Studies; D055252:Cell-Derived Microparticles / Q000378:metabolism*; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000097:blood* / Q000276:immunology; D018655:Lymphocyte Count; D008228:Lymphoma, Non-Hodgkin / Q000097:blood* / Q000276:immunology; D008297:Male; D008875:Middle Aged
chemical_list: D018941:Antigens, CD19; D018951:Antigens, CD20