title: The longitudinal association of vitamin D serum concentrations & adiposity phenotype.
abstract: Several cross-sectional studies have reported on the association between serum 25-hydroxy vitamin D concentrations (25(OH)D) and body mass index (BMI). We examined the longitudinal effect of BMI on serum 25(OH)D concentrations among 866 Puerto Rican adults living in the Greater Boston area: 246 men and 620 women, aged 45-75 years at baseline and 2 year. Our analyses showed negative correlations at two time points between BMI and serum 25(OH)D concentrations. The multivariate analysis showed that when predicting the change of serum 25(OH)D concentrations, baseline-BMI had significant inverse association (P<0.04) controlling for age, sex, and baseline-BMI. This association remained significant after adjusting for vitamin D supplement use, smoking, miles walked/day and alcohol intake (P<0.01). In conclusion, the major findings of the present study are obesity (1) was inversely associated with 25(OH)D at baseline; (2) with the change in serum 25(OH)D at 2-year in this population of older Puerto Rican adults living in the Boston area. This article is part of a Special Issue entitled '16th Vitamin D Workshop'.
authors: Bouvé College of Health Sciences. Northeastern University, Boston, MA 02115, USA. Electronic address: a.jamal-allial@neu.edu.
authors: Aziza
authors: A
authors: Jamal-Allial
authors: Bouvé College of Health Sciences. Northeastern University, Boston, MA 02115, USA.
authors: John L
authors: JL
authors: Griffith
authors: Clinical Laboratory & Nutritional Sciences, University of Massachusetts Lowell, Lowell, MA, USA.
authors: Katherine L
authors: KL
authors: Tucker
mesh_terms: D050154:Adiposity; D000328:Adult; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009765:Obesity / Q000097:blood* / Q000473:pathology; D010641:Phenotype; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D
keywords: BMI; Obesity; Puerto Rican; Serum 25(OH)D; Vitamin D