title: Recognizing hereditary colorectal cancer.
abstract: Colorectal cancer is the second-leading cause of cancer death in the United States. About 25% of patients have a personal or family history that suggests a hereditary colorectal cancer syndrome. This article describes the clinical and pathological characteristics of hereditary colorectal cancer, appropriate screening tests, and when to refer patients to a genetic counselor.
authors: Rochelle Paris Kline practices in the Department of Surgery, at the University of Pittsburgh Medical Center in Pittsburgh, with an emphasis on surgical oncology and colorectal surgery. The author has indicated no relationships to disclose relating to the content of this article.
authors: Rochelle Paris
authors: RP
authors: Kline
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000175:diagnosis* / Q000235:genetics; D003111:Colonic Polyps / Q000175:diagnosis / Q000235:genetics*; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000175:diagnosis* / Q000235:genetics; D045647:DNA Glycosylases / Q000235:genetics*; D005817:Genetic Counseling; D006801:Humans
chemical_list: D045647:DNA Glycosylases; C061738:mutY adenine glycosylase