title: Psychometric properties of the World Health Organization Quality Of Life Assessment-Brief in methadone patients: a validation study in northern Taiwan.
abstract: BACKGROUND
  Quality of life (QOL) is an important outcome measure in the treatment of heroin addiction. The Taiwan version of the World Health Organization Quality of Life assessment (WHOQOL-BREF [TW]) has been developed and studied in various groups, but not specifically in a population of injection drug users. The aim of this study was to analyze the psychometric properties of the WHOQOL-BREF (TW) in a sample of injection drug users undergoing methadone maintenance treatment.
  
  
  METHODS
  A total of 553 participants were interviewed and completed the instrument. Item-response distributions, internal consistency, corrected item-domain correlation, criterion-related validity, and construct validity through confirmatory factor analysis were evaluated.
  
  
  RESULTS
  The frequency distribution of the 4 domains of the WHOQOL-BREF (TW) showed no floor or ceiling effects. The instrument demonstrated adequate internal consistency (Cronbach's alpha coefficients were higher than 0.7 across the 4 domains) and all items had acceptable correlation with the corresponding domain scores (r = 0.32-0.73). Correlations (p < 0.01) of the 4 domains with the 2 benchmark items assessing overall QOL and general health were supportive of criterion-related validity. Confirmatory factor analysis yielded marginal goodness-of-fit between the 4-domain model and the sample data.
  
  
  CONCLUSIONS
  The hypothesized WHOQOL-BREF measurement model was appropriate for the injection drug users after some adjustments. Despite different patterns found in the confirmatory factor analysis, the findings overall suggest that the WHOQOL-BREF (TW) is a reliable and valid measure of QOL among injection drug users and can be utilized in future treatment outcome studies. The factor structure provided by the study also helps to understand the QOL characteristics of the injection drug users in Taiwan. However, more research is needed to examine its test-retest reliability and sensitivity to changes due to treatment.
authors: Tiffany Szu-Ting
authors: TS
authors: Fu
authors: Yung-Change
authors: YC
authors: Tuan
authors: Muh-Yong
authors: MY
authors: Yen
authors: Wei-Hsin
authors: WH
authors: Wu
authors: Chun-Wei
authors: CW
authors: Huang
authors: Wei-Ti
authors: WT
authors: Chen
authors: Chiang-Shan R
authors: CS
authors: Li
authors: Department of Health Promotion and Health Education, National Taiwan Normal University, No, 162, He-ping East Road, Section 1, Taipei 10610, Taiwan. tonylee@ntnu.edu.tw.
authors: Tony Szu-Hsien
authors: TS
authors: Lee
mesh_terms: D000328:Adult; D005260:Female; D006556:Heroin Dependence / Q000523:psychology / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D009294:Narcotics / Q000627:therapeutic use*; D058850:Opiate Substitution Treatment / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics; D011788:Quality of Life; D015819:Substance Abuse, Intravenous / Q000523:psychology / Q000534:rehabilitation; D013624:Taiwan
chemical_list: D009294:Narcotics; D008691:Methadone