title: Monitoring and managing hepatic disease in anaesthesia.
abstract: Patients with liver disease have multisystem organ dysfunction that leads to physiological perturbations ranging from hyperbilirubinaemia of no clinical consequence to severe coagulopathy and metabolic disarray. Patient-specific risk factors, clinical scoring systems, and surgical procedures stratify perioperative risk for these patients. The anaesthetic management of patients with hepatic dysfunction involves consideration of impaired drug metabolism, hyperdynamic circulation, perioperative hypoxaemia, bleeding, thrombosis, and hepatic encephalopathy.
authors: Department of Anesthesiology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
authors: D
authors: D
authors: Kiamanesh
authors: J
authors: J
authors: Rumley
authors: V K
authors: VK
authors: Moitra
mesh_terms: D000758:Anesthesia / Q000379:methods*; D002318:Cardiovascular Diseases / Q000209:etiology; D006801:Humans; D006932:Hyperbilirubinemia / Q000209:etiology; D006975:Hypertension, Portal / Q000150:complications; D007427:Intracranial Pressure; D008107:Liver Diseases / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D017590:Myelinolysis, Central Pontine / Q000209:etiology; D018570:Risk Assessment; D012720:Severity of Illness Index
keywords: liver; liver, cirrhosis; liver, disease; liver, function; liver, metabolism