title: Premature mortality due to cancer in Swietokrzyskie Province (Poland) in 1999-2010.
abstract: OBJECTIVE
  The purpose of the study was to analyze the level and the trends of premature mortality caused by selected cancers in Swietokrzyskie Province in years 1999-2010.
  
  
  METHODS
  The material for the study was the data published in the Swietokrzyskie Cancer Registry on the number of deaths caused by cancers as well as the information from the Central Statistical Office on the number of deaths due to general death causes in Swietokrzyskie Province in years 1999-2010. The premature mortality analysis was conducted with the use of PYLL indicator (PYLL - potential years of life lost). PYLL rate was calculated according to the method proposed by J. Romeder, according to which the premature mortality was defined as death before the age of 70. Time trends of PYLL rate and the average annual percent change (APC - annual percent change) were assessed usingjointpoint models as well as the Jointpoint Regression Program (Version 4.0.1 - January 2013).
  
  
  RESULTS
  In year 2010 cancers were responsible for 18.3% of PYLL in men and 48.1% in women. In years 1999-2010 PYLL rate in men decreased due to lung cancer (APC=0.75%) and stomach cancer (APC=1.2%). The increase in rate of PYLL was noted for colorectal cancer (APC=3.3%, p<0.05) and prostate cancer (APC=1.6%). In women, rate of PYLL increased due to lung cancer (APC=6.2%, p<0.05), colorectal cancer (APC=2.9%), breast cancer (APC=1.8%) and ovarian cancer (APC=0.15%). Rate of PYLL decreased due to cervical cancer (APC=4.3%, p<0.05) and stomach cancer (APC=1.5%).
  
  
  CONCLUSIONS
  During the analysed period the highest increase of premature mortality was observed in colorectal cancer in both sexes and lung cancer in women, a slightly smaller increase was noted for breast cancer and prostate cancer. What is particularly important is the trend and a slight decrease of premature mortality rate caused by lung cancer in men and its significant decrease for cervical cancer as well as stomach cancer in both sexes.
authors: Swietokrzyskie Cancer Centre, Kielce. stanislaw.gozdz@onkol.kielce.pl
authors: Stanislaw
authors: S
authors: Gózdz
authors: Michalina
authors: M
authors: Krzyzak
authors: Dominik
authors: D
authors: Maślach
authors: Malgorzata
authors: M
authors: Kolpak
authors: Monika
authors: M
authors: Wróbel
authors: Magdalena
authors: M
authors: Bielska-Lasota
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002423:Cause of Death / Q000639:trends*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D061213:Mortality, Premature / Q000639:trends*; D009369:Neoplasms / Q000453:epidemiology / Q000401:mortality*; D011044:Poland / Q000453:epidemiology; D055815:Young Adult