title: Is anti-D immunoglobulin still a frontline treatment option for immune thrombocytopenia?
abstract: A 5-year-old boy presents with platelet count of 2×10(9)/L and clinical and laboratory evidence of immune thrombocytopenia. He has epistaxis and oral mucosal bleeding. Complete blood count reveals isolated thrombocytopenia without any decline in hemoglobin and he is Rh+. You are asked if anti-D immunoglobulin is an appropriate initial therapy for this child given the 2010 Food and Drug Administration "black-box" warning.
authors: 1Hematology Service, Texas Children's Cancer Center, Houston, TX; and.
authors: Jenny M
authors: JM
authors: Despotovic
authors: Cindy E
authors: CE
authors: Neunert
mesh_terms: D002675:Child, Preschool; D004844:Epistaxis / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D006801:Humans; D007072:Immunoglobulin D; D008297:Male; D006472:Oral Hemorrhage / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy; D010976:Platelet Count; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000175:diagnosis
chemical_list: D007072:Immunoglobulin D