title: Preventing bacterial suicide: a novel toxin-antitoxin strategy.
abstract: In this issue of Molecular Cell, Aarke et al. (2013) identify a toxin-antitoxin system in Caulobacter crescentus that acts by a unique mechanism. The toxin, which blocks DNA replication, is constitutively degraded by ClpXP, and this degradation requires the antitoxin, a ClpXP adaptor.
authors: Laboratory of Molecular Biology, National Cancer Institute, Bethesda, MD 20892, USA.
authors: Monica
authors: M
authors: Markovski
authors: Laboratory of Molecular Biology, National Cancer Institute, Bethesda, MD 20892, USA. Electronic address: wickners@mail.nih.gov.
authors: Sue
authors: S
authors: Wickner
mesh_terms: D000992:Antitoxins / Q000235:genetics* / Q000378:metabolism*; D001427:Bacterial Toxins / Q000235:genetics* / Q000378:metabolism*; D004261:DNA Replication / Q000235:genetics*
chemical_list: D000992:Antitoxins; D001427:Bacterial Toxins