title: Lesson from hypomorphic recombination-activating gene (RAG) mutations: Why asymptomatic siblings should also be tested.
authors: Department of Pediatrics and Adolescent Medicine, University Hospital Ulm, Ulm, Germany. Electronic address: catharina.schuetz@uniklinik-ulm.de.
authors: Catharina
authors: C
authors: Schuetz
authors: Institute for Transfusion Medicine, University of Ulm, Ulm, Germany.
authors: Ulrich
authors: U
authors: Pannicke
authors: Department of Pediatrics and Adolescent Medicine, University Hospital Ulm, Ulm, Germany.
authors: Eva-Maria
authors: EM
authors: Jacobsen
authors: Labor Becker, Olgemöller und Kollegen, Munich, Germany.
authors: Siegfried
authors: S
authors: Burggraf
authors: Dr von Hauner University Children's Hospital, Munich, Germany.
authors: Michael H
authors: MH
authors: Albert
authors: Department of Pediatrics and Adolescent Medicine, University Hospital Ulm, Ulm, Germany.
authors: Manfred
authors: M
authors: Hönig
authors: Center for Child and Adolescent Health, HELIOS Klinikum Krefeld, Academic Hospital, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
authors: Tim
authors: T
authors: Niehues
authors: Department of Pediatric Oncology, Hematology, and Clinical Immunology, Children's Hospital, University Düsseldorf, Heinrich Heine University, Düsseldorf, Germany; Tavarlin AG, Darmstadt, Germany.
authors: Oliver
authors: O
authors: Feyen
authors: Centre of Chronic Immunodeficiency, University Hospital Freiburg, Freiburg, Germany.
authors: Stephan
authors: S
authors: Ehl
authors: Department of Pediatrics and Adolescent Medicine, University Hospital Ulm, Ulm, Germany.
authors: Klaus-Michael
authors: KM
authors: Debatin
authors: Department of Pediatrics and Adolescent Medicine, University Hospital Ulm, Ulm, Germany.
authors: Wilhelm
authors: W
authors: Friedrich
authors: Department of Pediatrics and Adolescent Medicine, University Hospital Ulm, Ulm, Germany.
authors: Ansgar S
authors: AS
authors: Schulz
authors: Institute for Transfusion Medicine, University of Ulm, Ulm, Germany; Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Service, Baden-Württemberg-Hessen, Germany.
authors: Klaus
authors: K
authors: Schwarz
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005820:Genetic Testing; D018398:Homeodomain Proteins / Q000235:genetics*; D006801:Humans; D008297:Male; D009154:Mutation; D011995:Recombination, Genetic; D016511:Severe Combined Immunodeficiency / Q000175:diagnosis* / Q000235:genetics*; D035781:Siblings
chemical_list: D018398:Homeodomain Proteins; C064658:RAG-1 protein