title: Tribological properties of biocompatible Ti-10W and Ti-7.5TiC-7.5W.
abstract: This study investigates and compares the microstructure, biocompatibility, and tribological properties of two different Ti-based composites, Ti-10W and Ti-7.5TiC-7.5W, with those of pure Ti for their potential use in biomedical applications. In particular, cold and hot isostatic-pressing and arc-melting methods were utilized and compared for the microstructure of the composites. Nano-scratch measurements and pin-on-disk wear tests were employed to understand their tribological behavior. As compared to pure Ti, Ti-10W and Ti-7.5TiC-7.5W showed significantly improved nano-scratch resistance (by 85 and 77%, respectively) and wear resistance (by 64 and 66%, respectively), in good agreement with hardness measurements. For biocompatibility examination, both microculture tetrazolium test (MTT) and water soluble tetrazolium (WST-1) test were used to quantify the cell viability of human osteoblasts and mouse fibroblasts on the materials. Both of the Ti-based composites showed acceptable biocompatibility in comparison with the pure Ti control.
authors: School of Advanced Materials Engineering, Kookmin University, 77 Jeongneung-ro, Seongbuk-gu, Seoul 136-702, Republic of Korea.
authors: Myounggeun
authors: M
authors: Choi
authors: School of Advanced Materials Engineering, Kookmin University, 77 Jeongneung-ro, Seongbuk-gu, Seoul 136-702, Republic of Korea.
authors: Eunji
authors: E
authors: Hong
authors: R&D Team, CG Bio Co., Sangdaewon-dong, Jungwon-gu, Seongnam-si, Kyunggi-do 462-807, Republic of Korea.
authors: Jungwon
authors: J
authors: So
authors: R&D Team, CG Bio Co., Sangdaewon-dong, Jungwon-gu, Seongnam-si, Kyunggi-do 462-807, Republic of Korea.
authors: Seokbeom
authors: S
authors: Song
authors: Department of Orthopedic Surgery, Daewoo General Hospital, 363 Dumo-dong, Geoje-si, Gyeongsangnam-do 656-711, Republic of Korea.
authors: Byoung-Suck
authors: BS
authors: Kim
authors: Biomaterials Unit, International Center for Materials Nanoarchitectonics, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.
authors: Akiko
authors: A
authors: Yamamoto
authors: School of Advanced Materials Engineering, Kookmin University, 77 Jeongneung-ro, Seongbuk-gu, Seoul 136-702, Republic of Korea.
authors: Yong-Suk
authors: YS
authors: Kim
authors: Department of Chemical and Biological Engineering, Korea University, Anam-dong, Seongbuk-gu, Seoul 136-701, Republic of Korea.
authors: Jinhan
authors: J
authors: Cho
authors: School of Advanced Materials Engineering, Kookmin University, 77 Jeongneung-ro, Seongbuk-gu, Seoul 136-702, Republic of Korea. Electronic address: heeman@kookmin.ac.kr.
authors: Heeman
authors: H
authors: Choe
mesh_terms: D000497:Alloys / Q000737:chemistry*; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000633:toxicity; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D008422:Materials Testing; D051379:Mice; D010006:Osteoblasts / Q000166:cytology / Q000187:drug effects; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*; D014414:Tungsten / Q000737:chemistry*
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; D014025:Titanium; D014414:Tungsten
keywords: Biocompatibility; Cell proliferation; Titanium; Wear mechanism