title: [Effects of gender on treatment strategies for elderly patients with acute coronary syndrome].
abstract: OBJECTIVE
  To explore the effects of gender on treatment strategies for elderly patients with acute coronary syndrome (ACS).
  
  
  METHODS
  March 2009 to March 2012, consecutive 619 aged ACS patients undergoing coronary angiography (CA) were screened at our hospital. There were 273 females and 346 males. Risk factors, ACS diagnosis, CA results, treatments and prognosis were compared between female and male groups.
  
  
  RESULTS
  The risk factors of body mass index, stroke history, smoking history, hemoglobin (Hb), serum cholesterol (TC), low density lipoprotein (LDL-C) and blood uric acid (UA) levels were significantly lower in female group than those in male group (P < 0.05). The morbidity of diabetes in female group was obviously higher than that in male group (27.8% vs 18.5%, P < 0.05). The prevalence of myocardial infarction history, percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) history in male group were significantly greater than that in female group (48.0% vs 39.9%, P < 0.05; 30.6% vs 22.3%, P < 0.05; 19.9% vs 10.3%, P < 0.01). The rate of combined multiple risk factors (3 or higher) increased significantly in female group (41.8% vs 29.8%, P < 0.05). The incidence of unstable angina pectoris (UAP) and non-ST segment elevation myocardial infarction (NSTEMI) in female group was greater, but there was no statistical significance. The rate of 3-vessel and calcification lesions in female group was significantly elevated compared with male group (36.26% vs 28.61%, P < 0.05). Regarding the choice of treatment strategy, conservative treatment was common in females, but there was no statistical significance between them. PCI, emergency PCI and selective CABG operation were performed more frequently in female group compared with male group (26.0% vs 14.2%, P < 0.01; 14.7% vs 6.6%, P < 0.01; 19.1% vs 7.7%, P < 0.01). The prognosis had no statistical significance between two groups.
  
  
  CONCLUSIONS
  The treatment strategies have certain limitations for female ACS patients. And an more aggressive treatment should be offered to improve the prognosis.
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China. Email: cuimeipingding@163.com.
authors.forename: Mei-ping
authors.initials: MP
authors.lastname: Cui
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China.
authors.forename: Wen-bin
authors.initials: WB
authors.lastname: Jiang
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China.
authors.forename: Ming-zhen
authors.initials: MZ
authors.lastname: Zhu
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China.
authors.forename: Xian-yan
authors.initials: XY
authors.lastname: Jiang
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China.
authors.forename: Ling-hua
authors.initials: LH
authors.lastname: Zhu
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Chang
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Guo
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China.
authors.forename: Song-tao
authors.initials: ST
authors.lastname: Wang
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China.
authors.forename: Chang-hong
authors.initials: CH
authors.lastname: Lu
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China.
authors.forename: Yi-ping
authors.initials: YP
authors.lastname: Ge
authors.affiliation: Cardiovascular Center, Qingdao Fuwai Hospital of Cardiovascular Diseases, Qingdao 266034, China.
authors.forename: Feng-xia
authors.initials: FX
authors.lastname: Qu
mesh_terms: D054058:Acute Coronary Syndrome / Q000628:therapy*; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis; D012307:Risk Factors; D012737:Sex Factors; D016896:Treatment Outcome