title: Evaluation of thyroid dysfunction in pregnant women with gestational and pre-gestational diabetes.
abstract: The aim of this study was to investigate thyroid function tests in Gestational Diabetes Mellitus (GDM) and pre-gestational DM and control group. Methodology : There were 61 pregnant diabetic women in study group and 35 pregnant women in control group. Serum T4, T3, T3RU, FTI, TSH and Anti TPO Ab were assessed in each person. Results : About 36% of patients had GDM and 64% pre-gestational DM. Thyroid dysfunction was detected in 18% of study group compared with 8.6% of control group (P = 0.2). There was Thyroid dysfunction in 4.5% of GDM and 25.6% of pregestational DM (P = 0.045). There was no statistically significant difference between thyroid dysfunction in GDM group and control group (P=0.99).27% of GDM and 36% of pregestational DM and 23% of control group had positive titer of Anti TPO Ab without statistically significant differences among the three groups. Conclusion : Thyroid dysfunction is prevalent in women with pre-gestational DM so, thyroid function should be evaluated in these patients during pregnancy. Rate of thyroid dysfunction in GDM patients is similar to normal pregnant control women. High prevalence of positive titer of TPO Ab was seen in diabetic and non-diabetic pregnant women.
authors.affiliation: Hajieh Shahbazian, Endocrinologist, Associate Professor, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Hajieh
authors.initials: H
authors.lastname: Shahbazian
authors.affiliation: Nahid Shahbazian, Gynecologist, Associate Professor, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Nahid
authors.initials: N
authors.lastname: Shahbazian
authors.affiliation: Mahnaz Rahimi Baniani, MD, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Mahnaz
authors.initials: M
authors.lastname: Rahimi Baniani
authors.affiliation: Leila Yazdanpanah, MD, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Leila
authors.initials: L
authors.lastname: Yazdanpanah
authors.affiliation: Seyed Mahmuod Latifi, MSc in Biostatistics, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Seyed Mahmuod
authors.initials: SM
authors.lastname: Latifi
keywords: Anti TPO Ab; Anti TgAb; GDM; Pregestational DM; Thyroid dysfunction