title: [Cognitive impairment in patients with coronary disease: relationship with clinical variables].
abstract: OBJECTIVE
  Coronary disease has been associated with cognitive disorders. We studied the presence of dysexecutive mild cognitive impairment in patients scheduled for coronary surgery.
  
  
  METHODS
  The executive function of 35 patients was evaluated (Trail Making Test). They were classified into 2 groups: normal performance or cognitive impairment, and we assessed the relationship with others variables (Mann-Whitney, chi-square and multiple regression analysis).
  
  
  RESULTS
  The dysexecutive cognitive impairment group (n=7; 20%) showed greater degree of angina (odds ratio [OR] 1.4, 95% confidence interval [95% CI] 1.1-2.6; P=.04), 3-vessels coronary artery disease (OR 1.3, 95% CI 1.08-3.6; P=.04) and body mass index (OR 1.56, 95% CI 1.16-3.65; P=.03) and lower diastolic blood pressure (OR 1.56, 95% CI 1.2-2.98; P=.02), hemoglobin (OR 2.03, 95% CI 1.18-4.05; P=.02) and hematocrit (OR 2.45, 95% CI 1.67-3.99; P<.001); these variables proved to be significant in the test performance considered as a dependent variable (R(2)=0.62).
  
  
  CONCLUSIONS
  We found a significant prevalence of dysexecutive mild cognitive impairment, which was associated with cardiovascular risk factors. We recommend assessment and monitoring of cognitive performance for probable neurological complications after cardiac surgery.
authors.affiliation: Servicio de Medicina Interna, Hospital Comarcal de La Axarquía, Vélez-Málaga, Málaga, España; Unidad de Neurofisiología Cognitiva, Centro de Investigaciones Médico-Sanitarias, Universidad de Málaga, CEI Andalucía Tech, IBIMA, Málaga, España. Electronic address: luismiguelpb@hotmail.com.
authors.forename: Luis M
authors.initials: LM
authors.lastname: Pérez-Belmonte
authors.affiliation: Unidad de Neurofisiología Cognitiva, Centro de Investigaciones Médico-Sanitarias, Universidad de Málaga, CEI Andalucía Tech, IBIMA, Málaga, España.
authors.forename: J Pablo
authors.initials: JP
authors.lastname: Lara
authors.affiliation: Servicio de Cirugía Cardíaca, Hospital Universitario Virgen de la Victoria, Málaga, España.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Olalla-Mercadé
authors.affiliation: Servicio de Cirugía Cardiovascular, Hospital Regional Universitario Carlos Haya, Málaga, España.
authors.forename: Julio
authors.initials: J
authors.lastname: Gutiérrez de Loma
authors.affiliation: Unidad de Neurofisiología Cognitiva, Centro de Investigaciones Médico-Sanitarias, Universidad de Málaga, CEI Andalucía Tech, IBIMA, Málaga, España.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Barbancho
authors.affiliation: Servicio de Medicina Interna, Hospital Comarcal de La Axarquía, Vélez-Málaga, Málaga, España.
authors.forename: Carlos M
authors.initials: CM
authors.lastname: San Román-Terán
mesh_terms: D000368:Aged; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D003327:Coronary Disease / Q000150:complications*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests
keywords: Cirugía; Coronary disease; Deterioro cognitivo leve; Enfermedad coronaria; Executive function; Función ejecutiva; Mild cognitive impairment; Surgery