title: PIIID-formed (Ti, O)/Ti, (Ti, N)/Ti and (Ti, O, N)/Ti coatings on NiTi shape memory alloy for medical applications.
abstract: (Ti, O)/Ti, (Ti, N)/Ti and (Ti, O, N)/Ti composite coatings were fabricated on NiTi shape memory alloy via plasma immersion ion implantation and deposition (PIIID). Surface morphology of samples was investigated using atomic force microscopy (AFM) and scanning electron microscopy (SEM). Cross-sectional morphology indicated that the PIIID-formed coatings were dense and uniform. X-ray diffraction (XRD) was used to characterize the phase composition of samples. X-ray photoelectron spectroscopy (XPS) results showed that the surface of coated NiTi SMA samples was Ni-free. Nanoindentation measurements and pin-on-disc tests were carried out to evaluate mechanical properties and wear resistance of coated NiTi SMA, respectively. For the in vitro biological assessment of the composite coatings in terms of cell morphology and cell viability, osteoblast-like SaOS-2 cells and breast cancer MCF-7 cells were cultured on NiTi SMA samples, respectively. SaOS-2 cells attached and spread better on coated NiTi SMA. Viability of MCF-7 cells showed that the PIIID-formed composite coatings were noncytotoxic and coated samples were more biocompatible than uncoated samples.
authors.affiliation: Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong; Institute of Microelectronics, Agency for Science, Technology and Research (A * STAR), Singapore.
authors.forename: Tao
authors.initials: T
authors.lastname: Sun
authors.affiliation: State Key Lab of Advanced Welding and Joining, Harbin Institute of Technology, China.
authors.forename: Lang-Ping
authors.initials: LP
authors.lastname: Wang
authors.affiliation: Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong.
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.affiliation: Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong.
authors.forename: Ho-Wang
authors.initials: HW
authors.lastname: Tong
authors.affiliation: Department of Orthopedics and Traumatology, The University of Hong Kong, Sassoon Road, Hong Kong.
authors.forename: William W
authors.initials: WW
authors.lastname: Lu
mesh_terms: D000497:Alloys / Q000009:adverse effects / Q000737:chemistry*; D001672:Biocompatible Materials / Q000009:adverse effects / Q000737:chemistry; D045744:Cell Line, Tumor; D002470:Cell Survival; D020099:Coated Materials, Biocompatible / Q000009:adverse effects / Q000737:chemistry; D006801:Humans; D007477:Ions / Q000737:chemistry; D061986:MCF-7 Cells; D008422:Materials Testing / Q000379:methods; D018625:Microscopy, Atomic Force / Q000379:methods; D008855:Microscopy, Electron, Scanning / Q000379:methods; D009532:Nickel / Q000009:adverse effects / Q000737:chemistry*; D010006:Osteoblasts / Q000502:physiology; D056951:Photoelectron Spectroscopy / Q000379:methods; D013499:Surface Properties; D014025:Titanium / Q000009:adverse effects / Q000737:chemistry*; D014961:X-Ray Diffraction / Q000379:methods
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible; D007477:Ions; D009532:Nickel; D014025:Titanium