title: White grain mycetoma caused by Scedosporium apiospermum in North India: a case report.
abstract: Mycetoma is chronic granulomatous infection of skin and subcutaneous tissue caused by both bacteria and fungi. We report a case of mycetoma caused by Scedosporium apiospermum in the right foot of a 45-year-old farmer in north India. The patient had a history of trauma in the sole of the right foot followed by discharge of white granules along with proximal progression. Scedosporium apiospermum was identified based on colony characteristics and microscopic features on slide culture. Mycetoma is a progressive disease. Foot is commonly affected in persons who walk barefoot, especially in south India. Untreated mycetoma progress and involve the underlying fasciae and tissues along with bones often resulting in loss of limb. By prompt and reliable diagnosis with corresponding antimicrobial administration, we can prevent further progression and limb disability.
authors.affiliation: 1Dept. of Microbiology, IMS, Banaras Hindu University, Varanasi, India.
authors.forename: Munesh Kumar
authors.initials: MK
authors.lastname: Gupta
authors.forename: Tuhina
authors.initials: T
authors.lastname: Banerjee
authors.forename: Dhirendra
authors.initials: D
authors.lastname: Kumar
authors.forename: Amit
authors.initials: A
authors.lastname: Rastogi
authors.forename: Ragini
authors.initials: R
authors.lastname: Tilak
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage; D003937:Diagnosis, Differential; D015725:Fluconazole / Q000008:administration & dosage*; D016523:Foot Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D006652:Histological Techniques / Q000379:methods; D006801:Humans; D008297:Male; D008682:Metatarsal Bones / Q000000981:diagnostic imaging; D008875:Middle Aged; D008271:Mycetoma / Q000150:complications / Q000188:drug therapy / Q000382:microbiology / Q000503:physiopathology; D011859:Radiography; D021681:Scedosporium / Q000302:isolation & purification*; D013639:Tarsal Bones / Q000000981:diagnostic imaging
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole
keywords: India; Scedosporium; foot; mycetoma; white grain