title: A cause of unbearably painful breast, diffuse dermal angiomatosis.
abstract: Diffuse dermal angiomatosis is a rare disorder, considered to be a variant of reactive cutaneous angioendotheliomatosis. The patients commonly present with severe intractable breast pain and characteristic reticular violaceous erythematous plaques with central ulcerations. Histologically, there is infiltration of the recticular dermis by endothelial cells due to excess vascular proliferation. Herein, we report a patient who presented with unbearable bilateral breast pain with characteristic "reticular vascular marking" of her breasts, who was diagnosed with diffuse dermal angiomatosis. We were able to successfully treat our patient with a tapered isoretinoin regimen.
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Virginia Commonwealth University School of Medicine, and Massey Cancer Center, Richmond, Virginia, USA.
authors.forename: Barbara J
authors.initials: BJ
authors.lastname: Adams
authors.affiliation: Division of Trauma, Critical Care, & Emergency Surgery, Department of Surgery, Virginia Commonwealth University School of Medicine, and Massey Cancer Center, Richmond, Virginia, USA.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Goldberg
authors.affiliation: Department of Pathology, Virginia Commonwealth University School of Medicine, and Massey Cancer Center, Richmond, Virginia, USA.
authors.forename: H Davis
authors.initials: HD
authors.lastname: Massey
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Virginia Commonwealth University School of Medicine, and Massey Cancer Center, Richmond, Virginia, USA.
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Takabe
keywords: Diffuse dermal angiomatosis (DDA); isoretinoin; reactive cutaneous angioendotheliomatosis (RAE)