title: [Molecular-genetic characterization of the Bhanja virus (BHAV) and the Razdan virus (RAZV) (Bunyaviridae, Phlebovirus) isolated from the Ixodes ticks Rhipicephalus bursa (Canestrini and Fanzago, 1878) and Dermacentor marginatus (Sulzer, 1776) in transcaucasus].
abstract: Two bunyaviruses, Bhanja (BHAV, LEIV-Az1818) isolated from the Ixodes ticks Rhipecephalus bursa (Canestrini and Fanzago, 1878) in Azerbaijan (1973) and Razdan (RAZV; strain LEIV-Arm2741) isolated from the Dermacentor marginatus (Sulzer, 1776) ticks in Armenia (1972), were de novo sequenced (on the Illumina platform). The amino acid identity between these viruses proteins were 95.8% (RdRp, L-segment), 90.3% (GnGc, M-segment), and 92.5% (N, S-segment). Thus, RAZV was classified to BHAV group. GnGc protein identity of RAZV withEuropean BHAV strains is more than 90%. With the African Forécariah virus (FORV) RAZV has 85% identity. BHAV LEIV-Az1818 is most closely related to the Indian strain BHAV IG690 (99%), while showing 90% identity with the European BHAV isolates. The genome structure of BHAV and RAZV is typical of the tick-transmitted phleboviruses. Based onthe result of the molecular-genetic and phylogenetic analysis RAZV has been classified as belonging to BHAVgroup in the genus Phlebovirus (Bunyaviridae).
authors.forename: S V
authors.initials: SV
authors.lastname: Al'khovskiĭ
authors.forename: D K
authors.initials: DK
authors.lastname: L'vov
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Shchelkanov
authors.forename: A M
authors.initials: AM
authors.lastname: Shchetinin
authors.forename: K G
authors.initials: KG
authors.lastname: Krasnoslobodtsev
authors.forename: P G
authors.initials: PG
authors.lastname: Deriabin
authors.forename: E I
authors.initials: EI
authors.lastname: Samokhvalov
authors.forename: A G
authors.initials: AG
authors.lastname: Botikov
authors.forename: V A
authors.initials: VA
authors.lastname: Zakarian
mesh_terms: D000818:Animals; D001136:Armenia; D001382:Azerbaijan; D003870:Dermacentor / Q000821:virology*; D016679:Genome, Viral / Q000235:genetics; D051379:Mice; D016856:Phlebovirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics*; D048494:Rhipicephalus / Q000821:virology*; D017423:Sequence Analysis, RNA
chemical_list: D012367:RNA, Viral