title: Cronkhite-Canada syndrome: review of the literature.
abstract: Cronkhite-Canada syndrome is a rare disease characterised by diffuse polyposis of the gastrointestinal tract, diarrhoea, weight loss, abdominal pain, cutaneous hyperpigmentation, dystrophic changes of fingernails, and alopecia. The etiology is probably autoimmune and diagnosis is based on history, physical examination, endoscopic findings of gastrointestinal polyposis, and histology. The disease is very rare; about 450 cases have been described in the literature so far. We present a review of the literature with our own picture documentation of this rare condition.
authors.affiliation: 2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Králové, University Teaching Hospital, Sokolska 581, 500 05 Hradec Králové, Czech Republic.
authors.forename: Marcela
authors.initials: M
authors.lastname: Kopáčová
authors.affiliation: Department of Gastroenterology, Vitkovice Hospital, Zalužanského 1192/15, 703 00 Ostrava-Vítkovice, Czech Republic.
authors.forename: Ondřej
authors.initials: O
authors.lastname: Urban
authors.affiliation: 2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Králové, University Teaching Hospital, Sokolska 581, 500 05 Hradec Králové, Czech Republic.
authors.forename: Jiří
authors.initials: J
authors.lastname: Cyrany
authors.affiliation: The Fingerland Department of Pathology, Charles University in Praha, Faculty of Medicine at Hradec Králové, University Teaching Hospital, Sokolska 581, 500 05 Hradec Králové, Czech Republic.
authors.forename: Jan
authors.initials: J
authors.lastname: Laco
authors.affiliation: 2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Králové, University Teaching Hospital, Sokolska 581, 500 05 Hradec Králové, Czech Republic.
authors.forename: Jan
authors.initials: J
authors.lastname: Bureš
authors.affiliation: 2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Králové, University Teaching Hospital, Sokolska 581, 500 05 Hradec Králové, Czech Republic.
authors.forename: Stanislav
authors.initials: S
authors.lastname: Rejchrt
authors.affiliation: 2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Králové, University Teaching Hospital, Sokolska 581, 500 05 Hradec Králové, Czech Republic.
authors.forename: Jolana
authors.initials: J
authors.lastname: Bártová
authors.affiliation: 2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Králové, University Teaching Hospital, Sokolska 581, 500 05 Hradec Králové, Czech Republic.
authors.forename: Ilja
authors.initials: I
authors.lastname: Tachecí