title: Immunoglobulin G4-related multiple cardiovascular lesions successfully treated with a combination of open surgery and corticosteroid therapy.
abstract: Immunoglobulin G4-related disease, a newly emerging systemic autoimmune disorder, can potentially involve the cardiovascular system. The standard treatment for immunoglobulin G4-related cardiovascular disease has not been established. We encountered a very rare case of an immunoglobulin G4-related inflammatory abdominal aortic aneurysm coexisting with a coronary artery aneurysm and periarteritis. The patient underwent surgical resection for the abdominal aortic aneurysm, followed by successful corticosteroid therapy for the coronary artery lesions. This is the first report of steroid-sensitive immunoglobulin G4-related coronary artery disease. A carefully planned treatment strategy for the multiple cardiovascular lesions was invaluable in the present case.
authors.affiliation: Department of Cardiovascular Surgery, Kitakyushu Municipal Medical Center, Fukuoka, Japan. Electronic address: kanomeikun@gmail.com.
authors.forename: Meikun
authors.initials: M
authors.lastname: Kan-o
authors.affiliation: Department of Cardiovascular Surgery, Kitakyushu Municipal Medical Center, Fukuoka, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Kado
authors.affiliation: Department of Internal Medicine, Kitakyushu Municipal Medical Center, Fukuoka, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Sadanaga
authors.affiliation: Department of Pathology, Kitakyushu Municipal Medical Center, Fukuoka, Japan.
authors.forename: Sadafumi
authors.initials: S
authors.lastname: Tamiya
authors.affiliation: Department of Pathology, Kitakyushu Municipal Medical Center, Fukuoka, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Toyoshima
authors.affiliation: Department of Cardiovascular Surgery, Kitakyushu Municipal Medical Center, Fukuoka, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Sakamoto
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000097:blood / Q000175:diagnosis / Q000276:immunology / Q000601:surgery*; D001027:Aortography / Q000379:methods; D001167:Arteritis / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D001327:Autoimmune Diseases / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D019917:Blood Vessel Prosthesis Implantation; D003131:Combined Modality Therapy; D003323:Coronary Aneurysm / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007150:Immunohistochemistry; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D015415:Biomarkers; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents