title: Successful treatment of bulky granulocytic sarcoma of the retroperitoneum with high-dose chemotherapy and autologous peripheral blood stem cell transplantation.
abstract: Granulocytic sarcoma is a rare disease that is rarely curable with conventional chemotherapy. This report describes a case of a patient with bulky granulocytic sarcoma of the retroperitoneum who was treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation without administering granulocyte colony-stimulating factor before stem cell collection. According to bone marrow assessment and imaging studies, the patient remained in complete remission at 5 years after transplantation. This case suggests that high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation is a therapeutic option for granulocytic sarcoma.
authors.affiliation: Department of Pathology, Osaka University Hospital.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Matsui
authors.forename: Michihiro
authors.initials: M
authors.lastname: Hidaka
authors.forename: Tetsuyuki
authors.initials: T
authors.lastname: Kiyokawa
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Murayama
authors.forename: Fumio
authors.initials: F
authors.lastname: Kawano
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D008297:Male; D036102:Peripheral Blood Stem Cell Transplantation; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis / Q000628:therapy*; D023981:Sarcoma, Myeloid / Q000175:diagnosis / Q000628:therapy*; D014057:Tomography, X-Ray Computed; D019172:Transplantation Conditioning; D014182:Transplantation, Autologous; D016896:Treatment Outcome