title: Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent.
abstract: An efficient method for the copper-catalyzed trifluoromethylation of terminal alkenes with an electrophilic trifluoromethylating reagent has been developed. The reactions proceeded smoothly to give trifluoromethylated alkenes in good to excellent yields. The results provided a versatile approach for the construction of Cvinyl-CF3 bonds without using prefunctionalized substrates.
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences,345 Lingling Road, Shanghai 200032, China ; Institute of Pharmacy and Pharmacology, University of South China, Hengyang, Hunan 421001, China.
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Wang
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences,345 Lingling Road, Shanghai 200032, China.
authors.forename: Jin-Hong
authors.initials: JH
authors.lastname: Lin
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences,345 Lingling Road, Shanghai 200032, China.
authors.forename: Cheng-Pan
authors.initials: CP
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences,345 Lingling Road, Shanghai 200032, China.
authors.forename: Ji-Chang
authors.initials: JC
authors.lastname: Xiao
authors.affiliation: Institute of Pharmacy and Pharmacology, University of South China, Hengyang, Hunan 421001, China.
authors.forename: Xing
authors.initials: X
authors.lastname: Zheng
keywords: alkenes; catalysis; copper; electrophilic trifluoromethylating reagent; trifluoromethylation