title: Fatty acid from the renewable sources: a promising feedstock for the production of biofuels and biobased chemicals.
abstract: With the depletion of the nonrenewable petrochemical resources and the increasing concerns of environmental pollution globally, biofuels and biobased chemicals produced from the renewable resources appear to be of great strategic significance. The present review described the progress in the biosynthesis of fatty acid and its derivatives from renewable biomass and emphasized the importance of fatty acid serving as the platform chemical and feedstock for a variety of chemicals. Due to the low efficient conversions of lignocellulosic biomass or carbon dioxide to fatty acid, we also put forward that rational strategies for the production of fatty acid and its derivatives should further derive from the consideration of whole bioprocess (pretreatment, saccharification, fermentation, separation), multiscale analysis and interdisciplinary combinations (omics, kinetics, metabolic engineering, synthetic biology, fermentation and so on).
authors.affiliation: CAS Key Laboratory of Bio-based Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China. Electronic address: liuhui@qibebt.ac.cn.
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.affiliation: CAS Key Laboratory of Bio-based Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Cheng
authors.affiliation: CAS Key Laboratory of Bio-based Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.
authors.forename: Mo
authors.initials: M
authors.lastname: Xian
authors.affiliation: CAS Key Laboratory of Bio-based Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.
authors.forename: Yujin
authors.initials: Y
authors.lastname: Cao
authors.affiliation: CAS Key Laboratory of Bio-based Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Fang
authors.affiliation: CAS Key Laboratory of Bio-based Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China. Electronic address: zouhb@qibebt.ac.cn.
authors.forename: Huibin
authors.initials: H
authors.lastname: Zou
mesh_terms: D056804:Biofuels; D018533:Biomass; D004926:Escherichia coli; D005227:Fatty Acids / Q000032:analysis / Q000378:metabolism; D005285:Fermentation; D008031:Lignin; D060847:Metabolic Engineering; D053858:Metabolic Networks and Pathways
chemical_list: D056804:Biofuels; D005227:Fatty Acids; C036909:lignocellulose; D008031:Lignin
keywords: Biobased chemicals; Biofuels; Fatty acid; Interdisciplinary study; Multiscale analysis; Renewable biomass