title: Weight reduction and maintenance in a specialized outpatient health care center.
abstract: CONCLUSIONS
  
  
  
  OBJECTIVE
  To prospectively evaluate the amount of weight loss and subsequent maintenance and to identify correlates of successful weight reduction in overweight and obese outpatients treated in a specialized health care center.
  
  
  METHODS
  A treatment program involving diet, exercise and behavior modification was provided in an outpatient setting. Twenty-four treatment courses with a total of 177 participants (age: 45.5 ± 12.2 year; BMI: 36.7 ± 5.6 kg/m(2)) were run.
  
  
  METHODS
  Weight and baseline characteristics were recorded at start of program; weight was re-assessed at the end of treatment and 1 year after the end of treatment.
  
  
  RESULTS
  Patients achieved a significant weight loss of 5.6 ± 7.9 kg (5.1 ± 6.4% of initial body weight) in the course of 1 year. An average of 80.8% or 4.8 kg of initial weight loss was maintained a year after treatment, representing a significant weight regain. A higher initial BMI, intake of venlafaxin, a higher percentage of course attendance, course completion and hypertension were associated with greater weight loss. The interaction of the specific treatment course and the percentage of attendance explained 25% of the variance of percental total weight loss.
  
  
  CONCLUSIONS
  Significant weight losses can be achieved by overweight and obese patients after a treatment program in specialized health care addressing diet, exercise and behavioral aspects. Weight loss maintenance remains difficult for patients. The specific treatment group itself and attendance of course sessions are critical for weight loss and should be considered in the design and evaluation of group-based treatment programs.
authors.affiliation: University Hospital Tübingen, Department of Psychosomatic Medicine and Psychotherapy, Osianderstr. 5, 72076 Tübingen, Germany. Electronic address:katrin.giel@med.uni-tuebingen.de.
authors.forename: Katrin E
authors.initials: KE
authors.lastname: Giel
authors.affiliation: University Hospital Tübingen, Department of Psychosomatic Medicine and Psychotherapy, Osianderstr. 5, 72076 Tübingen, Germany.
authors.forename: Maria
authors.initials: M
authors.lastname: Binkele
authors.affiliation: University Hospital Tübingen, Department of Psychosomatic Medicine and Psychotherapy, Osianderstr. 5, 72076 Tübingen, Germany.
authors.forename: Sandra
authors.initials: S
authors.lastname: Becker
authors.affiliation: University Hospital Tübingen, Department of Psychosomatic Medicine and Psychotherapy, Osianderstr. 5, 72076 Tübingen, Germany.
authors.forename: Petra
authors.initials: P
authors.lastname: Stübler
authors.affiliation: University Hospital Tübingen, Department of Psychosomatic Medicine and Psychotherapy, Osianderstr. 5, 72076 Tübingen, Germany.
authors.forename: Stephan
authors.initials: S
authors.lastname: Zipfel
authors.affiliation: University Hospital Tübingen, Department of Psychosomatic Medicine and Psychotherapy, Osianderstr. 5, 72076 Tübingen, Germany.
authors.forename: Paul
authors.initials: P
authors.lastname: Enck