title: Pyoderma gangrenosum: skin grafting and hyperbaric oxygen as adjuvants in the treatment of a deep and extensive ulcer.
abstract: Pyoderma gangrenosum is a rare dermatosis of unknown etiology and variable clinical presentation. The disease is challenging for the medical staff, from the frequent diagnostic difficulties to the lack of scientific evidence with a good level to support the management of extensive and refractory cases. Our patient is a 50 year-old man with an extensive and deep ulcer on the left leg, which exemplifies the therapeutic difficulties inherent to the disease and who, fortunately, has progressed with excellent result after association of hyperbaric oxygen therapy and skin grafting to the immunosuppression therapy initially proposed.
authors.affiliation: State University of Londrina, Dermatology Service, LondrinaParaná, Brazil.
authors.forename: Fernanda Mendes
authors.initials: FM
authors.lastname: Araújo
authors.affiliation: State University of Londrina, Dermatology Service, LondrinaParaná, Brazil.
authors.forename: Rogério Nabor
authors.initials: RN
authors.lastname: Kondo
authors.affiliation: State University of Londrina, Dermatology Service, LondrinaParaná, Brazil.
authors.forename: Lorivaldo
authors.initials: L
authors.lastname: Minelli
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D017511:Pyoderma Gangrenosum / Q000473:pathology / Q000628:therapy*; D016038:Skin Transplantation / Q000379:methods*; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D000305:Adrenal Cortex Hormones