title: Adequate prenatal care reduces the risk of adverse pregnancy outcomes in women with history of infertility: a nationwide population-based study.
abstract: OBJECTIVE
  To investigate the effects of various measures of prenatal care on adverse pregnancy outcomes in women with a history of infertility.
  
  
  METHODS
  A retrospective cohort study.
  
  
  METHODS
  Data were derived by linking 2 large nationwide population-based datasets, the National Health Insurance Research Database and Taiwan Birth Certificate Registry. The study sample included 15,056 women with an infertility diagnosis and 60,224 randomly selected women without infertility matched to the study sample by maternal age. A conditional logistic regression analysis was performed for the analysis.
  
  
  RESULTS
  Women diagnosed with infertility respectively had 1.39 (95% CI, 1.06~1.83), 1.15 (95% CI, 1.08~1.24), 1.13 (95% CI, 1.08~1.18), and 1.08 (95% CI, 1.05~1.12) higher odds of having very low birth weight (VLBW) babies, preterm births, labor complications, and cesarean sections (CSs) compared to women without infertility. Inadequate numbers of total and major prenatal visits and late initiation of prenatal care increased the risks of adverse pregnancy outcomes in women with infertility, especially the risk of a VLBW baby. However, no significant associations were found for the risks of adverse birth outcomes in infertile women with adequate prenatal care compared to fertile women with adequate care.
  
  
  CONCLUSIONS
  Study findings suggest that adequate prenatal care can reduce the risk of adverse pregnancy outcomes in women with infertility.
authors.affiliation: School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan.
authors.forename: Raushan
authors.initials: R
authors.lastname: Alibekova
authors.affiliation: Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Jian-Pei
authors.initials: JP
authors.lastname: Huang
authors.affiliation: School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan.
authors.forename: Yi-Hua
authors.initials: YH
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology*; D008875:Middle Aged; D016017:Odds Ratio; D011159:Population Surveillance; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011295:Prenatal Care; D012042:Registries; D012189:Retrospective Studies; D012306:Risk; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult