title: [Chronic rhinosinusitis and tissue remodeling].
abstract: Chronic rhinosinusitis is a common health problem of otorhinolaryngology head and neck surgery, and is characterized by persistent inflammation of the nasal and paranasal mucosal linings. In recent years, tissue remodeling has been demonstrated to play an important role in the development of chronic rhinosinusitis, and furthermore transforming growth factor-beta1 (TGF-beta1) may play a pivotal role in this progress. This review will summarize the current knowledge on the roles of tissue remodeling in chronic rhinosinusitis, therefore to offer reference to the research and help to make diagnosis and give treatment for this disease.
authors.forename: Li
authors.initials: L
authors.lastname: Fang
authors.forename: Yucheng
authors.initials: Y
authors.lastname: Yang
mesh_terms: D056151:Airway Remodeling; D002908:Chronic Disease; D006801:Humans; D007249:Inflammation; D012852:Sinusitis / Q000378:metabolism / Q000473:pathology*; D053773:Transforming Growth Factor beta1 / Q000378:metabolism
chemical_list: D053773:Transforming Growth Factor beta1