title: Urinary metabolomic changes as a predictive biomarker of asthma exacerbation.
authors.affiliation: Serviço de Pneumologia, Hospitais da Universidade de Coimbra, Coimbra, Portugal; Centre of Pneumology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal. Electronic address: cl_loureiro@hotmail.com.
authors.forename: Claudia Chaves
authors.initials: CC
authors.lastname: Loureiro
authors.affiliation: CICECO, Departamento de Química, Universidade de Aveiro, Aveiro, Portugal.
authors.forename: Iola F
authors.initials: IF
authors.lastname: Duarte
authors.affiliation: QOPNA, Departamento de Química, Universidade de Aveiro, Aveiro, Portugal.
authors.forename: Joana
authors.initials: J
authors.lastname: Gomes
authors.affiliation: CICECO, Departamento de Química, Universidade de Aveiro, Aveiro, Portugal.
authors.forename: Joana
authors.initials: J
authors.lastname: Carrola
authors.affiliation: QOPNA, Departamento de Química, Universidade de Aveiro, Aveiro, Portugal.
authors.forename: António S
authors.initials: AS
authors.lastname: Barros
authors.affiliation: CICECO, Departamento de Química, Universidade de Aveiro, Aveiro, Portugal.
authors.forename: Ana M
authors.initials: AM
authors.lastname: Gil
authors.affiliation: University Hospital Hôpital Arnaud de Villeneuve, Montpellier, France, and Inserm, CESP Centre for Research in Epidemiology and Population Health, U1018, Respiratory and Environmental Epidemiology team, Villejuif, France.
authors.forename: Jean
authors.initials: J
authors.lastname: Bousquet
authors.affiliation: Centre of Pneumology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
authors.forename: Ana Todo
authors.initials: AT
authors.lastname: Bom
authors.affiliation: QOPNA, Departamento de Química, Universidade de Aveiro, Aveiro, Portugal.
authors.forename: Sílvia M
authors.initials: SM
authors.lastname: Rocha
mesh_terms: D000328:Adult; D000368:Aged; D001249:Asthma / Q000175:diagnosis* / Q000276:immunology; D015415:Biomarkers / Q000652:urine; D002331:Carnitine / Q000652:urine*; D015331:Cohort Studies; D018450:Disease Progression; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D055432:Metabolomics; D008744:Methylamines / Q000652:urine*; D008875:Middle Aged; D018384:Oxidative Stress; D010865:Pilot Projects; D011446:Prospective Studies; D013912:Threonine / Q000652:urine*
chemical_list: D015415:Biomarkers; D008744:Methylamines; D013912:Threonine; C005855:trimethyloxamine; D002331:Carnitine