title: Multiple microvenular hemangioma: A case report.
abstract: The current study reports a case of multiple microvenular hemangioma (MH). A 35-year-old male presented with dark red maculopapules on the trunk and limbs that had been apparent for 5 years. The number of lesions exceeded 100 in total. A histological examination demonstrated multiple, irregular, branching venules in the dermis, without any endothelial atypia. On immunohistochemical analysis of the vascular structures, the endothelial cells stained positive for CD31, CD34 and factor VIII, and the perivascular cells stained positive for SMA and HHF-35. These observations were consistent with a diagnosis of MH, and should be differentiated from the most common differential diagnosis of patch-stage Kaposi's sarcoma. There was no clear effect following topical application of recombinant human interferon α-2b gel.
authors.affiliation: Department of Dermatology, Cangzhou Central Hospital, Cangzhou, Hebei 061001, P.R. China.
authors.forename: Dong Fang
authors.initials: DF
authors.lastname: Ai
authors.affiliation: Department of Dermatology, Tianjin Medical University, General Hospital, Tianjin 300052, P.R. China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.affiliation: Tianjin Medical University, Tianjin 300052, P.R. China.
authors.forename: Aikaj
authors.initials: A
authors.lastname: Jindal
authors.affiliation: Department of Dermatology, Cangzhou Central Hospital, Cangzhou, Hebei 061001, P.R. China.
authors.forename: Ping
authors.initials: P
authors.lastname: Li
keywords: microvenular hemangioma