title: Inhibition of enamel demineralization by buffering effect of S-PRG filler-containing dental sealant.
abstract: The buffering capacity and inhibitory effects on enamel demineralization of two commercially available dental sealants were evaluated in this study. The effects of filler particles were also examined. Disks of enamel and cured sealant materials of BeautiSealant (silica or S-PRG filler) or Teethmate F-1 were incubated in lactic acid solutions (pH 4.0) for 1-6 d. The pH changes and amounts of ions released in the solutions were assessed, and enamel surfaces were observed using a scanning electron microscope. The pH of the solution with BeautiSealant (S-PRG filler) was neutralized from pH 4.0 to pH 6.1 (after incubation for 1 d) and from pH 4.0 to pH 6.7 (after incubation for 6 d). In addition, no release of calcium ions was detected and the enamel surface was morphologically intact in scanning electron microscopy images. However, the pH of the solution with Teethmate F-1 remained below pH 4.0 during incubation from days 1 to 6. Calcium release was increased in solutions up to and after 6 d of incubation. Scanning electron microscopy images showed that the structures of hydroxyapatite rods were exposed at the specimen surfaces as a result of demineralization. Ions released from S-PRG filler-containing dental sealant rapidly buffered the lactic acid solution and inhibited enamel demineralization.
authors.affiliation: Division of Biomaterials and Bioengineering Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kaga
authors.forename: Shinichi
authors.initials: S
authors.lastname: Kakuda
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Ida
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Toshima
authors.forename: Masanori
authors.initials: M
authors.lastname: Hashimoto
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Endo
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Sano
mesh_terms: D000535:Aluminum / Q000737:chemistry; D000818:Animals; D001464:Barium / Q000737:chemistry; D002021:Buffers; D002118:Calcium / Q000737:chemistry; D002417:Cattle; D003188:Composite Resins / Q000737:chemistry; D003743:Dental Enamel / Q000648:ultrastructure*; D017886:Durapatite / Q000737:chemistry; D005459:Fluorides / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D019344:Lactic Acid / Q000737:chemistry / Q000494:pharmacology; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D010895:Pit and Fissure Sealants / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry; D011109:Polymethacrylic Acids / Q000737:chemistry; D011140:Polyurethanes / Q000737:chemistry; D012117:Resins, Synthetic / Q000737:chemistry; D012825:Silicon / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry; D012964:Sodium / Q000737:chemistry; D013324:Strontium / Q000737:chemistry; D013997:Time Factors; D017001:Tooth Demineralization / Q000473:pathology / Q000517:prevention & control*
chemical_list: D002021:Buffers; D003188:Composite Resins; D008689:Methacrylates; D010895:Pit and Fissure Sealants; D011109:Polymethacrylic Acids; D011140:Polyurethanes; D012117:Resins, Synthetic; C099291:teethmate-FTM; C029824:urethane dimethacrylate luting resin; C020946:triethylene glycol dimethacrylate; D001464:Barium; D019344:Lactic Acid; D011092:Polyethylene Glycols; D012822:Silicon Dioxide; D017886:Durapatite; D012964:Sodium; D000535:Aluminum; D005459:Fluorides; D002118:Calcium; D013324:Strontium; D012825:Silicon
keywords: S-PRG filler; buffering capacity; demineralization; dental sealants; ion release