title: Neurologic complications of cardiac tests and procedures.
abstract: Arterial or central venous vascular access is the cornerstone of invasive cardiac diagnosis, monitoring, and therapeutics. Although procedural safety has significantly improved with protocols perfected over decades of use, their prevalence renders even the uncommon neurologic complication clinically relevant. Serious peripheral nerve complications result from direct or indirect nerve injuries in the setting of a hematoma or compartment syndrome. Functional outcome is dependent upon prompt diagnosis and early treatment, so proceduralists should be aware of the relevant anatomy and early signs of nerve injury. Ischemic stroke is the most common central nervous system complication of diagnostic and therapeutic cardiac catheterization, and is presumed to be due to embolization of atherosclerotic plaque or thrombus dislodged during guiding catheter manipulation, platelet-fibrin thrombus that forms on the catheters, or air that appears during catheter flushing. Acute neurologic deterioration after thrombolysis for acute myocardial infarction should be presumed to be an intracranial hemorrhage until proven otherwise. The ideal angiography suite of the future is patientcentric and multipurpose, coordinating diagnostic and therapeutic strategies for multivascular disease, allowing for multispecialty collaboration, and, in the event of a neurologic complication of a cardiac procedure, facilitating the various treating physicians to converge efficiently upon the patient.
authors.affiliation: Department of Neurology, Case Western Reserve University School of Medicine and Stroke and Cerebrovascular Center, University Hospitals-Case Medical Center, Cleveland, OH, USA. Electronic address: Cathy.Sila@UHhospitals.org.
authors.forename: Cathy
authors.initials: C
authors.lastname: Sila
mesh_terms: D006328:Cardiac Catheterization / Q000009:adverse effects*; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D009422:Nervous System Diseases / Q000209:etiology* / Q000266:history; D015912:Thrombolytic Therapy / Q000009:adverse effects*; D014652:Vascular Diseases / Q000175:diagnosis* / Q000628:therapy
keywords: Vascular access procedures; cardiac catheterization; cerebral embolism; cerebral hemorrhage; peripheral nerve injury; thrombolysis