title: Iminium ion-enamine cascade cyclizations: facile access to structurally diverse azacyclic compounds and natural products.
abstract: A one-pot, mild, two-component iminium ion-enamine cascade reaction to construct structurally diverse azacyclic frameworks from l-proline and l-pipecolic acid, and its application to indolizidine and quinolizidine alkaloids and azasteroids, is reported.
authors.affiliation: Department of Chemistry, Université de Montréal , Station Centre Ville, C.P. 6128, Montreal, Quebec, H3C 3J7, Canada.
authors.forename: Stephen
authors.initials: S
authors.lastname: Hanessian
authors.forename: Amit Kumar
authors.initials: AK
authors.lastname: Chattopadhyay
mesh_terms: D000588:Amines / Q000737:chemistry*; D001372:Aza Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D007097:Imines / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D000588:Amines; D001372:Aza Compounds; D001688:Biological Products; D001643:Bridged Bicyclo Compounds; D007097:Imines; D007477:Ions