title: [Bacteriological spectrum and drug susceptibility of pus from severe intra-abdominal infected patients with abdominal trauma].
abstract: OBJECTIVE
  To retrospectively analyze the bacteriological spectrum and drug susceptibility of pus flora from abdominal traumatic patients with severe intra-abdominal infection.
  
  
  METHODS
  A total of 41 severe intra-abdominal infected patients with abdominal trauma were recruited to collect 123 abdominal pus specimens. And the results of laboratory microbiology and drug sensitivity were analyzed with the WHONET 5.4 software.
  
  
  RESULTS
  A total of 297 strains of bacteria were isolated at (7.2 ± 2.3) strains for each patient. Gram-positive bacteria accounted for 44.1% (131/297) , Gram-negative bacteria 55.2% (164/297) and fungi 0.7% (2/297). The top five isolates were Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Enterococcus faecalis and Pseudomonas aeruginosa. Those antibiotics highly sensitive (>90%) to Escherichia coli included cefoperazone (91%), imipenem (98%); highly sensitive to Gram-positive cocci included teicoplanin (100%) and linezolid (100%). Staphylococcus aureus was 100% sensitive to vancomycin. The agents with a high susceptibility to Klebsiella pneumonia included imipenem (100%) and amikacin (79%). Ciprofloxacin (90%) had the highest sensitivity to Pseudomonas aeruginosa.
  
  
  CONCLUSIONS
  The predominant bacteria of causing severe intra-abdominal infection of traumatic patients is Gram-negative bacteria, but the infection of Gram-positive bacteria, especially the ratio of Staphylococcus aureus infection is also comparatively high. Cefoperazone, ciprofloxacin, imipenem, vancomycin, teicoplanin and linezolid have higher antibacterial activity.
authors.affiliation: Department of General Surgery, School of Medicine, Nanjing University; General PLA Hospital of Nanjing Military Command, Nanjing 210002, China.
authors.forename: Shao-yi
authors.initials: SY
authors.lastname: Zhang
authors.affiliation: Department of General Surgery, School of Medicine, Nanjing University; General PLA Hospital of Nanjing Military Command, Nanjing 210002, China. Email: liys@medmail.com.cn.
authors.forename: You-sheng
authors.initials: YS
authors.lastname: Li
authors.affiliation: Department of General Surgery, School of Medicine, Nanjing University; General PLA Hospital of Nanjing Military Command, Nanjing 210002, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of General Surgery, School of Medicine, Nanjing University; General PLA Hospital of Nanjing Military Command, Nanjing 210002, China.
authors.forename: Wen-kui
authors.initials: WK
authors.lastname: Yu
authors.affiliation: Department of General Surgery, School of Medicine, Nanjing University; General PLA Hospital of Nanjing Military Command, Nanjing 210002, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Li
authors.affiliation: Department of General Surgery, School of Medicine, Nanjing University; General PLA Hospital of Nanjing Military Command, Nanjing 210002, China.
authors.forename: Jie-shou
authors.initials: JS
authors.lastname: Li
mesh_terms: D018784:Abdominal Abscess / Q000209:etiology / Q000382:microbiology*; D000007:Abdominal Injuries / Q000150:complications / Q000382:microbiology*; D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003428:Cross Infection / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012189:Retrospective Studies; D013492:Suppuration / Q000382:microbiology; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents