title: [Early compliance and efficacy of sublingual immunotherapy in patients with allergic rhinitis].
abstract: OBJECTIVE
  The study aimed to investigate the efficacy and adverse effects of sublingual immunotherapy (SLIT) of dust mite drops to allergic rhinitis with mite allergy. The compliance and satisfaction of SLIT were also assessed.
  
  
  METHODS
  One hundred and three patients of allergic rhinitis sensitive to dust mites were treated with SLIT for 6 months or more. The symptom questionnaire,including items on rhinorrhea, sneezing, nasal obstruction, itchy nose, olfactory disturbance, eye discomfort and sleep disturbance were obtained before and 6 months after SLIT. The patients' satisfaction and adverse effects were also investigated.
  
  
  RESULTS
  Seventy-five of the 103 patients insist on SLIT for more than 6 months and completed the questionnaire. The duration of receiving SLIT was 9.8 months on average (range from 6 to 13 months). The satisfaction rate was 89.3%. The drop-out rate of SLIT was 31.0%.
  
  
  CONCLUSIONS
  The subjective symptoms were improved with SLIT in patients with allergic rhinitis sensitive to dust mites. The drop out rate was high despite of the symptomatic improvement.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, General Hospital of Ji'nan Military Region, Ji'nan, 250031, China.
authors.forename: Genhong
authors.initials: G
authors.lastname: Li
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, General Hospital of Ji'nan Military Region, Ji'nan, 250031, China.
authors.forename: Chunsheng
authors.initials: C
authors.lastname: Zhu
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, General Hospital of Ji'nan Military Region, Ji'nan, 250031, China.
authors.forename: Jianqiu
authors.initials: J
authors.lastname: Chen
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Tongji University Affiliated Tongji Hospital.
authors.forename: Shaoqing
authors.initials: S
authors.lastname: Yu
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, General Hospital of Ji'nan Military Region, Ji'nan, 250031, China.
authors.forename: Jiafeng
authors.initials: J
authors.lastname: Lin
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, General Hospital of Ji'nan Military Region, Ji'nan, 250031, China.
authors.forename: Baodong
authors.initials: B
authors.lastname: Wang
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, General Hospital of Ji'nan Military Region, Ji'nan, 250031, China.
authors.forename: Ben
authors.initials: B
authors.lastname: Ye
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, General Hospital of Ji'nan Military Region, Ji'nan, 250031, China.
authors.forename: Suosheng
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, General Hospital of Ji'nan Military Region, Ji'nan, 250031, China.
authors.forename: Xiujuan
authors.initials: X
authors.lastname: Zhao
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, General Hospital of Ji'nan Military Region, Ji'nan, 250031, China.
authors.forename: Tian
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, General Hospital of Ji'nan Military Region, Ji'nan, 250031, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: He
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D017060:Patient Satisfaction; D065631:Rhinitis, Allergic; D012221:Rhinitis, Allergic, Perennial / Q000523:psychology* / Q000628:therapy*; D063729:Sublingual Immunotherapy / Q000523:psychology*; D016896:Treatment Outcome; D055815:Young Adult