title: Fe5C2 nanoparticles with high MRI contrast enhancement for tumor imaging.
abstract: An ancient material for magnetic resonance (MR) imaging: For the first time, Fe5C2 is prepared as colloidal stable nanoparticles with good aqueous stability. The nanoparticles boast strong magnetization, excellent chemical inertness, low toxicity, and one of the highest r2 relaxivities reported to date. These nanoparticles hold great potential in MR imaging as well as in other biomedical areas.
authors.affiliation: Department of Chemistry and Bio-Imaging, Research Center (BIRC), University of Georgia, Athens, GA, 30602, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Tang
authors.forename: Zipeng
authors.initials: Z
authors.lastname: Zhen
authors.forename: Ce
authors.initials: C
authors.lastname: Yang
authors.forename: Luning
authors.initials: L
authors.lastname: Wang
authors.forename: Taku
authors.initials: T
authors.lastname: Cowger
authors.forename: Hongmin
authors.initials: H
authors.lastname: Chen
authors.forename: Trever
authors.initials: T
authors.lastname: Todd
authors.forename: Khan
authors.initials: K
authors.lastname: Hekmatyar
authors.forename: Qun
authors.initials: Q
authors.lastname: Zhao
authors.forename: Yanglong
authors.initials: Y
authors.lastname: Hou
authors.forename: Jin
authors.initials: J
authors.lastname: Xie
mesh_terms: D000818:Animals; D017554:Carbon Compounds, Inorganic; D045744:Cell Line, Tumor; D003287:Contrast Media; D006801:Humans; D058085:Iron Compounds; D008279:Magnetic Resonance Imaging; D051379:Mice; D053758:Nanoparticles / Q000648:ultrastructure; D009369:Neoplasms / Q000175:diagnosis*; D019047:Phantoms, Imaging
chemical_list: D017554:Carbon Compounds, Inorganic; D003287:Contrast Media; D058085:Iron Compounds; C541825:iron carbide
keywords: integrins; iron carbides; magnetic properties; magnetic resonance imaging; nanoparticles