title: [Effect of overweight on cardiac function in children].
abstract: OBJECTIVE
  It is known that obesity is related to heart failure. Asymptomatic left ventricular diastolic dysfunction (LVDD) is associated with the development of heart failure. The relationship between subclinical LVDD and overweight in children is not clear. The purpose of this study was to evaluate the effect of body mass index (BMI) and waist circumference on left ventricular mass index (LVMI) and LVDD in overweight children.
  
  
  METHODS
  A total of 153 children were enrolled in the study. Of these, 91 were normal weight (age-adjusted BMI: 15-85 percentile), and 62 were overweight (age-adjusted BMI: 85-95 percentile). After measuring two-dimensional and M-mode echocardiographic variables, left and right ventricle diastolic functions were assessed by conventional and tissue Doppler imaging.
  
  
  RESULTS
  Compared to controls, overweight children had increased left atrium, aortic and left ventricular diameters, left ventricular wall thickness, LVM and LVMI, and septal mitral annulus e', septal e'/a', lateral e', lateral e'/a', lateral tricuspid annulus e', and e'/a' values. There were negative correlations between tissue Doppler diastolic parameters (septal mitral annulus e', lateral mitral annulus e', lateral tricuspid annulus e', septal mitral annulus e'/a', lateral mitral annulus e'/a', and lateral tricuspid annulus e'/a') and BMI, waist circumference, insulin, HOMA index, as well as systolic and diastolic blood pressure. Positive correlations were found between LVMI and BMI and between LVMI and waist circumference. BMI was found to be the predictor of decreased mitral anulus septal e', septal e'/a', lateral e', lateral e'/a'.
  
  
  CONCLUSIONS
  Compared with normal-weight children, overweight children have decreased LV diastolic function. BMI is associated with a reduction in LV diastolic function in overweight children.
authors.affiliation: Department of Cardiology, Namık Kemal University Faculty of Medicine, Tekirdağ, Turkey. srfalpsoy@hotmail.com.
authors.forename: Seref
authors.initials: S
authors.lastname: Alpsoy
authors.affiliation: Department of Cardiology, Namık Kemal University Faculty of Medicine, Tekirdağ, Turkey.
authors.forename: Aydın
authors.initials: A
authors.lastname: Akyüz
authors.affiliation: Department of Cardiology, Namık Kemal University Faculty of Medicine, Tekirdağ, Turkey.
authors.forename: Dursun Cayan
authors.initials: DC
authors.lastname: Akkoyun
authors.affiliation: Department of Child Health and Diseases, Namık Kemal University Faculty of Medicine, Tekirdağ, Turkey.
authors.forename: Burçin
authors.initials: B
authors.lastname: Nalbantoğlu
authors.affiliation: Department of Biostatistics, Namık Kemal University Faculty of Medicine, Tekirdağ, Turkey.
authors.forename: Birol
authors.initials: B
authors.lastname: Topçu
authors.affiliation: Department of Cardiology, Namık Kemal University Faculty of Medicine, Tekirdağ, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Değirmenci
authors.affiliation: Department of Child Health and Diseases, Namık Kemal University Faculty of Medicine, Tekirdağ, Turkey.
authors.forename: Burcu
authors.initials: B
authors.lastname: Ozdilek
authors.affiliation: Department of Child Health and Diseases, Namık Kemal University Faculty of Medicine, Tekirdağ, Turkey.
authors.forename: Mustafa Metin
authors.initials: MM
authors.lastname: Donma
mesh_terms: D001794:Blood Pressure / Q000502:physiology; D002648:Child; D015150:Echocardiography, Doppler; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008297:Male; D009765:Obesity / Q000503:physiopathology; D050177:Overweight / Q000503:physiopathology*; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology