title: Effect of polymorphisms in candidate genes on carcass and meat quality traits in double muscled Piemontese cattle.
abstract: The aim of this study was to investigate the association between 10 candidate genes and carcass weight and conformation, carcass daily gain, and meat quality (pH, color, cooking loss, drip loss and shear force) in 990 double-muscled Piemontese young bulls. Animals were genotyped at each of the following genes: growth hormone, growth hormone receptor, pro-opiomelanocortin, pro-opiomelanocortin class 1 homeobox 1, melanocortin-4 receptor, corticotrophin-releasing hormone, diacylglycerol O-acyltransferase-1, thyroglobulin, carboxypeptidase E and gamma-3 regulatory subunit of the AMP-activated protein kinase. All the investigated SNPs had additive effects which were relevant for at least one of the traits. Relevant associations between the investigated SNPs and carcass weight, carcass daily gain and carcass conformation were detected, whereas associations of SNPs with meat quality were moderate. Results confirmed some of previously reported associations, but diverged for others. Validation in other cattle breeds is required to use these SNPs in gene-assisted selection programs for enhancement of carcass traits and meat quality.
authors.affiliation: Department of Agriculture, Food, Natural Resources, Animals and Environment, University of Padova, Viale dell'Università 16, 35020, Legnaro, Padova, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Ribeca
authors.affiliation: Department of Comparative Biomedicine and Food Science, University of Padova, Viale dell'Università 16, 35020, Legnaro, Padova, Italy. Electronic address: valentina.bonfatti@unipd.it.
authors.forename: V
authors.initials: V
authors.lastname: Bonfatti
authors.affiliation: Department of Agriculture, Food, Natural Resources, Animals and Environment, University of Padova, Viale dell'Università 16, 35020, Legnaro, Padova, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Cecchinato
authors.affiliation: Piemontese Cattle Breeders Association (ANABoRaPi), strada Trinità 32/a, Carrù, 12061, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Albera
authors.affiliation: Department of Agriculture, Food, Natural Resources, Animals and Environment, University of Padova, Viale dell'Università 16, 35020, Legnaro, Padova, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Gallo
authors.affiliation: Department of Comparative Biomedicine and Food Science, University of Padova, Viale dell'Università 16, 35020, Legnaro, Padova, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Carnier
mesh_terms: D055372:AMP-Activated Protein Kinases / Q000235:genetics; D000818:Animals; D001835:Body Weight; D001947:Breeding; D043423:Carboxypeptidase H / Q000235:genetics; D002417:Cattle; D003116:Color; D003296:Cooking; D051048:Diacylglycerol O-Acyltransferase / Q000235:genetics; D005511:Food Handling; D063427:Food Quality; D005787:Gene Frequency; D005838:Genotype; D013006:Growth Hormone / Q000235:genetics; D006863:Hydrogen-Ion Concentration; D008297:Male; D008460:Meat / Q000032:analysis*; D018482:Muscle, Skeletal / Q000737:chemistry; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide; D011333:Pro-Opiomelanocortin / Q000235:genetics; D044105:Receptor, Melanocortin, Type 4 / Q000235:genetics; D011986:Receptors, Somatotropin / Q000235:genetics; D013954:Thyroglobulin / Q000235:genetics; D050817:Transcription Factor Pit-1 / Q000235:genetics
chemical_list: D044105:Receptor, Melanocortin, Type 4; D011986:Receptors, Somatotropin; D050817:Transcription Factor Pit-1; D011333:Pro-Opiomelanocortin; D013006:Growth Hormone; D013954:Thyroglobulin; D051048:Diacylglycerol O-Acyltransferase; D055372:AMP-Activated Protein Kinases; D043423:Carboxypeptidase H
keywords: Association; Candidate gene; Carcass; Meat quality; Piedmontese; Single nucleotide polymorphism