title: A new view of integrin αIIbβ3 bound to membrane.
abstract: In this issue of Blood, Choi et al report a 3-dimensional (3D) reconstruction model of integrin aIIbb3 in its latent state which challenges the existing paradigm and provides new insights into the mechanism of integrin activation.
authors.affiliation: CLEVELAND CLINIC.
authors.forename: Jun
authors.initials: J
authors.lastname: Qin
authors.forename: Edward F
authors.initials: EF
authors.lastname: Plow
mesh_terms: D006801:Humans; D021621:Imaging, Three-Dimensional; D008956:Models, Chemical; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D019039:Platelet Glycoprotein GPIIb-IIIa Complex