title: Effect of the time to intervention on the outcome of thrombosed dialysis access grafts managed percutaneously.
abstract: OBJECTIVE
  We aimed to investigate the effect of the time interval from the clinical presentation of a thrombosed dialysis access graft to intervention on procedure success.
  
  
  METHODS
  Records from two academic institutions for patients who underwent percutaneous thrombectomy of occluded surgical hemodialysis graft access sites in interventional radiology from 2006 to 2011 were reviewed retrospectively. The following data were recorded: gender, age, time and date of the initial request for a thrombectomy and the procedure, age of the surgical access, angiographic outcome, and clinical outcome (successful or unsuccessful postinterventional dialysis). Univariate and multivariate logistic regression were used to evaluate whether the time to intervention significantly affected the study endpoint.
  
  
  RESULTS
  In total, 268 percutaneous thrombectomies were performed in 139 patients. Of these 224 (83.5%) were categorized as successful and 44 (16.4%) as unsuccessful. The time to intervention was 19.9±30.1 vs. 22±35 hours for successful and unsuccessful procedures, respectively. The difference between the two was not significant, and there were also no significant differences in covariate distributions between successful and unsuccessful outcomes.
  
  
  CONCLUSIONS
  During the first 72 hours following clinical presentation of a thrombosed dialysis access graft, time to intervention may be considered independent of procedure outcome.
authors.affiliation: From the Department of Radiology (J.D.P. e-mail: jdprologo@hotmail.com), University Hospitals of Cleveland, Cleveland, Ohio, USA; The Division of Vascular and Interventional Radiology (J.D.P.), Urological Institute, Anesthesia Pain Management, and the National Center for Regenerative Medicine, and the Departments of Radiology (J.K., A.P.), and Biomedical Engineering (D.C.), University Hospitals Case Medical Center, Cleveland, Ohio, USA; the Department of Radiology (G.M.), Johns Hopkins Medical Center, Baltimore, Maryland, USA.
authors.forename: John David
authors.initials: JD
authors.lastname: Prologo
authors.forename: Gregory
authors.initials: G
authors.lastname: Minwell
authors.forename: Jillian
authors.initials: J
authors.lastname: Kent
authors.forename: Ali
authors.initials: A
authors.lastname: Pirasteh
authors.forename: David
authors.initials: D
authors.lastname: Corn
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012189:Retrospective Studies; D017131:Thrombectomy / Q000379:methods*; D013927:Thrombosis / Q000209:etiology / Q000601:surgery*; D061665:Time-to-Treatment; D062666:Vascular Access Devices / Q000009:adverse effects