title: The role of double-balloon enteroscopy following capsule endoscopy in diagnosis of obscure Small intestinal diseases.
abstract: OBJECTIVE
  The aim of this study was to evaluate the detection rate accuracy of Double-balloon Enteroscopy (DBE) after Capsule Endoscopy (CE) in patients with suspected small bowel diseases.
  
  
  METHODS
  From January 2009 to March 2012, sixty-two patients with obscure small bowel diseases who underwent CE followed by DBE were included in this study. Introduction of the endoscope by DBE was either orally or anally according to CE.
  
  
  RESULTS
  Sixty-two patients are reported. The overall detection rate of small bowel diseases using CE was 70.9% (44/62). Sixty-eight DBE procedures following capsule endoscopy were carried out, There was no significant difference (χ(2)=0.6739, P>0.05) of Positive findings between CE and CE +DBE. Furthermore, the detection rate of small bowel diseases in patients with obscure small intestinal bleeding using CE +DBE (90.9%, 30/33) was superior to that of CE (78.8%, 26/33); χ(2)=1.8857, P>0.05.
  
  
  CONCLUSIONS
  Capsule Endoscopy (CE) can cover the whole GI tract and provide the selection of the route of Double-balloon enteroscopy (DBE). DBE can also serve as a good complementary approach after an initial imaging using CE. It can verify the findings of CE and provide therapeutic intervention. Using of CE followed by DBE is effective in the diagnosis and management of patients with obscure small bowel diseases.
authors.affiliation: Chen Tian Min, Department of Gastroenterology, The first people's Hospital of Nantong, Jiangsu, China 226001.
authors.forename: Chen
authors.initials: C
authors.lastname: Tian Min
authors.affiliation: Xu Li Hua, Department of Gastroenterology, The first people's Hospital of Nantong, Jiangsu, China 226001.
authors.forename: Xu
authors.initials: X
authors.lastname: Li Hua
authors.affiliation: Ji Ying Lin, Department of Gastroenterology, The first people's Hospital of Nantong, Jiangsu, China 226001.
authors.forename: Ji
authors.initials: J
authors.lastname: Ying Lin
authors.affiliation: Yang Yan Mei, Department of Gastroenterology, The first people's Hospital of Nantong, Jiangsu, China 226001.
authors.forename: Yang
authors.initials: Y
authors.lastname: Yan Mei
authors.affiliation: Lu Fei, Department of Gastroenterology, The first people's Hospital of Nantong, Jiangsu, China 226001.
authors.forename: Lu
authors.initials: L
authors.lastname: Fei
authors.affiliation: Qian Jun Bo, Department of Gastroenterology, The first people's Hospital of Nantong, Jiangsu, China 226001.
authors.forename: Qian
authors.initials: Q
authors.lastname: Jun Bo
keywords: Capsule Endoscopy; Diagnosis; Double-Balloon Enteroscopy; Small Intestinal Disease