title: Biosynthesis and Total Synthesis Studies on The Jadomycin Family of Natural Products.
abstract: Jadomycins are unique angucycline polyketides, which are produced by soil bacteriaStreptomyces venezuelaeunder specific nutrient and environmental conditions. Their unique structural complexity and biological activities have engendered extensive study of the jadomycin class of natural compounds in terms of biological activity, biosynthesis, and synthesis. This review outlines the recent developments in the study of the synthesis and biosynthesis of jadomycins.
authors.affiliation: Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, 02115, Homepage: http://nuweb9.neu.edu/odoherty/
authors.forename: Ehesan U
authors.initials: EU
authors.lastname: Sharif
authors.affiliation: Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, 02115, Homepage: http://nuweb9.neu.edu/odoherty/
authors.forename: George A
authors.initials: GA
authors.lastname: O'Doherty
keywords: Biosynthesis; Carbasugar; Digitoxose; Jadomycin; Phenanthridine Ring System; Total Synthesis