title: Diagnostic value of ischemia-modified albumin in acute coronary syndrome and acute ischemic stroke.
abstract: OBJECTIVE
  To investigate diagnostic value of ischemia-modified albumin (IMA) levels in patients applying to emergency with symptoms of acute coronary syndrome (ACS) and acute ischemic stroke (AIS).
  
  
  METHODS
  Two patient groups (ACS and AIS) and a control group were constituted. The study was discontinued upon reaching 30 patients in each group. Following patient approval at the initial visit, a total of 10 ml venous blood sample was obtained from all patients with a high clinical suspicion of ACS and AIS. The Troponin I and the IMA levels were determined in the blood samples.
  
  
  RESULTS
  Statistically significant higher IMA values were determined in the patient groups compared to the control group (p<0.001 for both groups). No statistically significant correlation was found between the IMA and the Troponin I values in the ACS and the AIS groups (p>0.05 for both groups). The sensitivity of IMA was 83% and 87% for ACS and AIS, respectively. The specificity of IMA was 90% and 87% for ACS and AIS, respectively.
  
  
  CONCLUSIONS
  The sensitivity and specificity values, determined according to the optimal cut-off values in the groups demonstrated that IMA could be a useful diagnostic marker in ACS and AIS patients.
authors.affiliation: Birsen Ertekin, Department of Emergency Medicine, Beyhekim State Hospital, Konya, Turkey.
authors.forename: Birsen
authors.initials: B
authors.lastname: Ertekin
authors.affiliation: Sedat Kocak, Department of Emergency Medicine, Meram Medical Faculty, Konya University, Konya, Turkey.
authors.forename: Sedat
authors.initials: S
authors.lastname: Kocak
authors.affiliation: Zerrin Defne Dundar, Department of Emergency Medicine, Konya Research and Training Hospital, Konya, Turkey.
authors.forename: Zerrin
authors.initials: Z
authors.lastname: Defne Dundar
authors.affiliation: Sadik Girisgin, Department of Emergency Medicine, Meram Medical Faculty, Konya University, Konya, Turkey.
authors.forename: Sadik
authors.initials: S
authors.lastname: Girisgin
authors.affiliation: Basar Cander, Department of Emergency Medicine, Meram Medical Faculty, Konya University, Konya, Turkey.
authors.forename: Basar
authors.initials: B
authors.lastname: Cander
authors.affiliation: Mehmet Gul, Department of Emergency Medicine, Meram Medical Faculty, Konya University, Konya, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Gul
authors.affiliation: Sibel Doseyici, Department of Biochemistry, Meram Medical Faculty, Konya University, Konya, Turkey.
authors.forename: Sibel
authors.initials: S
authors.lastname: Doseyici
authors.affiliation: Idris Mehmetoglu, Department of Biochemistry, Meram Medical Faculty, Konya University, Konya, Turkey.
authors.forename: Idris
authors.initials: I
authors.lastname: Mehmetoglu
authors.affiliation: Tahir Kemal Sahin, Department of Public Health, Meram Medical Faculty, Konya University, Konya, Turkey.
authors.forename: Tahir
authors.initials: T
authors.lastname: Kemal Sahin
keywords: Acute coronary syndrome; Acute ischemic stroke; Emergency medicine; Ischemia; Ischemia-modified albumin