title: Al3+ selective colorimetric and fluorescent red shifting chemosensor: application in living cell imaging.
abstract: We report the development of a fluorescent probe based on the benzothiazole unit to monitor intracellular Al(3+) levels in living cells. The fluorescent probe exhibits a fluorescence response towards Al(3+) under physiological conditions with high sensitivity and selectivity and even facilitates naked-eye detection of Al(3+). The fluorescence intensity was significantly quenched with red shifting upon addition of 0.5 equiv. of Al(3+). The simple and cost effective receptor avails rapid detection of Al(3+) ions at concentrations as low as 0.42 μM and is expected to be effective for the design of efficient biological sensor.
authors.affiliation: School of Chemical Sciences, North Maharashtra University, Jalgaon, 425001 MS, India. kuwaras@gmail.com.
authors.forename: Rahul
authors.initials: R
authors.lastname: Patil
authors.forename: Anuradha
authors.initials: A
authors.lastname: Moirangthem
authors.forename: Ray
authors.initials: R
authors.lastname: Butcher
authors.forename: Narinder
authors.initials: N
authors.lastname: Singh
authors.forename: Anupam
authors.initials: A
authors.lastname: Basu
authors.forename: Kundan
authors.initials: K
authors.lastname: Tayade
authors.forename: Umesh
authors.initials: U
authors.lastname: Fegade
authors.forename: Dilip
authors.initials: D
authors.lastname: Hundiwale
authors.forename: Anil
authors.initials: A
authors.lastname: Kuwar
mesh_terms: D000535:Aluminum / Q000032:analysis* / Q000737:chemistry*; D002470:Cell Survival; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D003116:Color; D003124:Colorimetry; D006367:HeLa Cells; D006801:Humans; D008958:Models, Molecular; D008968:Molecular Conformation; D057054:Molecular Imaging / Q000379:methods*; D013050:Spectrometry, Fluorescence
chemical_list: D000535:Aluminum