title: Renal relevant radiology: radiologic imaging in autosomal dominant polycystic kidney disease.
abstract: Autosomal-dominant polycystic kidney disease is a systemic disorder and the most common hereditary renal disease, which is characterized by cyst growth, progressive renal enlargement, and development of renal failure. The cystic nature of autosomal dominant polycystic kidney disease and its renal and extrarenal complications (kidney stones, cyst hemorrhage, intracerebral aneurysm, liver cysts, cardiac valve abnormalities, etc.) give radiologic imaging studies a central role in the management of these patients. This article reviews the indications, comparative use, and limitation of various imaging modalities (ultrasonography, magnetic resonance imaging, computerized tomography scan, Positron emission tomography scan, and renal scintigraphy) for the diagnosis and management of complications in autosomal dominant polycystic kidney disease. Finally, this work provides evidence for the value of total kidney volume to predict disease progression in autosomal dominant polycystic kidney disease.
authors.affiliation: Departments of Medicine and, †Radiology, Emory University School of Medicine, Atlanta, Georgia.
authors.forename: Frederic
authors.initials: F
authors.lastname: Rahbari-Oskoui
authors.forename: Ankush
authors.initials: A
authors.lastname: Mittal
authors.forename: Pardeep
authors.initials: P
authors.lastname: Mittal
authors.forename: Arlene
authors.initials: A
authors.lastname: Chapman
mesh_terms: D000293:Adolescent; D000328:Adult; D003952:Diagnostic Imaging / Q000379:methods; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016891:Polycystic Kidney, Autosomal Dominant / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D049268:Positron-Emission Tomography; D011379:Prognosis; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D055815:Young Adult