title: Analysis of complex phthalic acid based polyesters by the combination of size exclusion chromatography and matrix-assisted laser desorption/ionization mass spectrometry.
abstract: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) was used in conjunction with size exclusion chromatography (SEC) to investigate a model polyester system based on phthalic anhydride-1,2-propylene glycol. The polyesters were synthesized with a 30% molar excess of glycol, with kinetic samples being removed during different intervals of the polyesterification reaction. SEC was used to track the course of the reaction by determining the molecular weight and molecular weight distributions before subsequent off-line coupling with MALDI-TOF MS as a selective detection method to determine the chemical composition, identify the functionality type distributions as well as assist in assigning structural conformations. Mass spectrometry analysis proved to be a highly effective tool to facilitate the identification of the narrowly dispersed fractions obtained from the chromatographic separations as well as serve as a core method to investigate the heterogeneous nature of the bulk kinetic samples. Through the hyphenation of these sophisticated polymer characterization techniques, information on the molecular heterogeneity of the model polyesters, showing a complex variety of possible distributions, was obtained.
authors.affiliation: Department of Chemistry and Polymer Science, University of Stellenbosch, Private Bag X1, 7602 Matieland, South Africa.
authors.forename: Nadine O
authors.initials: NO
authors.lastname: Pretorius
authors.affiliation: Fraunhofer Institute for Structural Durability and System Reliability (LBF), Division Plastics, Schlossgartenstraße 6, D-64289 Darmstadt, Germany.
authors.forename: Karsten
authors.initials: K
authors.lastname: Rode
authors.affiliation: Kansai Plascon Research Centre, 7602 Stellenbosch, South Africa.
authors.forename: Jaylin M
authors.initials: JM
authors.lastname: Simpson
authors.affiliation: Department of Chemistry and Polymer Science, University of Stellenbosch, Private Bag X1, 7602 Matieland, South Africa. Electronic address: hpasch@sun.ac.za.
authors.forename: Harald
authors.initials: H
authors.lastname: Pasch
keywords: Chemical composition; Matrix-assisted laser desorption/ionization mass spectrometry; Molar mass; Phthalic anhydride; Polyesters; Size exclusion chromatography