title: Direct electrophilic N-trifluoromethylthiolation of amines with trifluoromethanesulfenamide.
abstract: The CF3SN moiety is a substituent with interesting properties. However, there is no easy synthetic access to molecules bearing this group. The trifluoromethanesulfenamide is a new reagent for the electrophilic trifluoromethylthiolation which reacts easily with amines to obtain trifluoromethylsulfanylamines with good yields.
authors.affiliation: Institute of Chemistry and Biochemistry (ICBMS - UMR CNRS 5246), Université de Lyon, Université Lyon 1, CNRS, 43 Bd du 11 novembre 1918 - 69622 Lyon, France ; CERMEP - in vivo imaging, Groupement Hospitalier Est, 59 Bd Pinel - 69003 Lyon, France.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Alazet
authors.affiliation: Institute of Chemistry and Biochemistry (ICBMS - UMR CNRS 5246), Université de Lyon, Université Lyon 1, CNRS, 43 Bd du 11 novembre 1918 - 69622 Lyon, France.
authors.forename: Kevin
authors.initials: K
authors.lastname: Ollivier
authors.affiliation: Institute of Chemistry and Biochemistry (ICBMS - UMR CNRS 5246), Université de Lyon, Université Lyon 1, CNRS, 43 Bd du 11 novembre 1918 - 69622 Lyon, France ; CERMEP - in vivo imaging, Groupement Hospitalier Est, 59 Bd Pinel - 69003 Lyon, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Billard
keywords: amine; fluorine; organo-fluorine; trifluoromethanesulfenamide; trifluoromethylsulfanylamine; trifluoromethylthiolation