title: Gender and outcomes of carotid artery interventions.
abstract: The benefits of carotid artery revascularization in women have been debated since the publication of large randomized clinical trials comparing carotid endarterectomy (CEA) to medical therapy. Institutional series have historically had an underrepresentation of women and/or have lacked power for adequate analysis. Recent evidence from large databases reveals possible gender-based differences in outcomes of carotid artery stenting versus CEA. In this review, we evaluated clinical articles from 1991 to 2012, using Pubmed and Web of Science, which addressed gender and outcomes of carotid artery revascularization procedures. Our goal was to determine whether gender is associated with adverse outcomes following carotid artery interventions in patients with carotid artery disease.
authors.affiliation: 1Division of Vascular and Endovascular Surgery, University of California Davis Medical Center, Sacramento, CA, USA.
authors.forename: Nasim
authors.initials: N
authors.lastname: Hedayati
authors.forename: Misty D
authors.initials: MD
authors.lastname: Humphries
authors.forename: Wei
authors.initials: W
authors.lastname: Zhou
mesh_terms: D017130:Angioplasty / Q000009:adverse effects / Q000295:instrumentation; D002340:Carotid Artery Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D016894:Endarterectomy, Carotid / Q000009:adverse effects; D005260:Female; D054624:Health Status Disparities; D006801:Humans; D008297:Male; D012008:Recurrence; D012307:Risk Factors; D012737:Sex Factors; D015607:Stents; D020521:Stroke / Q000209:etiology; D013997:Time Factors; D016896:Treatment Outcome
keywords: carotid artery disease; endarterectomy; gender; outcomes; stenting