title: Survival outcomes of patients with temporal bone squamous cell carcinoma with different invasion patterns.
abstract: BACKGROUND
  The correlation between the survival rate and various invasion patterns of patients with temporal bone squamous cell carcinoma (SCC) is unclear. This study was performed to compare the survival outcomes of these patients to disclose the correlation.
  
  
  METHODS
  The cases of 39 patients with temporal bone SCC who underwent surgery between January 2004 and December 2012 were reviewed.
  
  
  RESULTS
  The 2-year overall survival rate was 56.9%, and it was 22.3% for patients with stage IV disease, and 100% for patients with stage I-III disease. Patients with parotid invasion (n = 11), temporomandibular joint (TMJ) involvement (n = 8), and middle ear surgery (n = 7) before temporal bone malignancies were diagnosed had poor survival with statistical difference.
  
  
  CONCLUSIONS
  Patients with parotid gland, TMJ involvement, and previous middle ear surgery for chronic otitis media had poor outcomes.
authors.affiliation: Department of Otology and Skull Base Surgery, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China.
authors.forename: Bingbin
authors.initials: B
authors.lastname: Xie
authors.forename: Ting
authors.initials: T
authors.lastname: Zhang
authors.forename: Chunfu
authors.initials: C
authors.lastname: Dai
mesh_terms: D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000401:mortality* / Q000473:pathology* / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000401:mortality* / Q000473:pathology* / Q000628:therapy; D003392:Cranial Sinuses / Q000473:pathology; D004388:Dura Mater / Q000473:pathology; D004432:Ear, Middle / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010033:Otitis Media / Q000601:surgery; D010306:Parotid Gland / Q000473:pathology; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D013701:Temporal Bone / Q000473:pathology*; D013704:Temporomandibular Joint / Q000473:pathology
keywords: external auditory canal; malignant tumor; squamous cell carcinoma; survival rates; temporal bone malignant