title: Growth charts and long-term sequelae in extreme preterm infants--from full-term age to 10 years.
abstract: OBJECTIVE
  To describe growth pattern from full-term age to 10 years in infants born before 26 weeks of gestation.
  
  
  METHODS
  This retrospective longitudinal cohort contained 123 children from Karolinska Hospital, Stockholm, during 1990-2002. Length/height (Ht), weight (Wt) and head circumference (HC) were recorded monthly during the first year, every 3 months until 2 years and yearly thereafter, but HC at 15 months and at median age of 8.1/9.7 years (range 2-14) in boys/girls.
  
  
  RESULTS
  For boys/girls at birth, the mean Z-score for Ht was -0.2/-0.2, for Wt 0.0/-0.2 and for HC 0.0/-0.3. At term, the mean Z-score for Ht was -3.8/-3.1, for Wt -3.0/-2.5 and for HC -1.7/-1.2. At 1 year, the mean Z-score for Ht was-1.3/-1.3, for Wt -1.9/-1.7 and for HC -1.2/-1.0. At 2 years, the mean Z-score for Ht was -1.3/-1.1, for Wt -1.6/-1.2 and at 10 years for Ht -0.7/-0.4; that was on average -0.3 below mid-parental height; for Wt -0.2/-0.2. Long-term sequelae were found in 48% of the boys and 34% of the girls.
  
  
  CONCLUSIONS
  By 10 years of age, the attained mean Ht was in accordance with their genetic potential and almost half of these children had significant long-term sequelae.
authors.affiliation: Paediatric Endocrinology Unit, Department for Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. eva.horemuzova@ki.se.
authors.forename: Eva
authors.initials: E
authors.lastname: Horemuzova
authors.forename: Per
authors.initials: P
authors.lastname: Amark
authors.forename: Lena
authors.initials: L
authors.lastname: Jacobson
authors.forename: Olle
authors.initials: O
authors.lastname: Söder
authors.forename: Lars
authors.initials: L
authors.lastname: Hagenäs
mesh_terms: D001724:Birth Weight; D002648:Child; D002657:Child Development; D002675:Child, Preschool; D005260:Female; D057238:Growth Charts; D006801:Humans; D007223:Infant; D062071:Infant, Extremely Premature / Q000254:growth & development*; D007231:Infant, Newborn; D008137:Longitudinal Studies; D008297:Male; D012016:Reference Values; D012189:Retrospective Studies
keywords: Growth charts; preterm infant; sequelae