title: Ancient signals: comparative genomics of green plant CDPKs.
abstract: Calcium-dependent protein kinases (CDPKs) are multifunctional proteins that combine calcium-binding and signaling capabilities within a single gene product. This unique versatility enables multiple plant biological processes to be controlled, including developmental programs and stress responses. The genome of flowering plants typically encodes around 30 CDPK homologs that cluster in four conserved clades. In this review, we take advantage of the recent availability of genome sequences from green algae and early land plants to examine how well the previously described CDPK family from angiosperms compares to the broader evolutionary states associated with early diverging green plant lineages. Our analysis suggests that the current architecture of the CDPK family was shaped during the colonization of the land by plants, whereas CDPKs from ancestor green algae have continued to evolve independently.
authors.affiliation: Département de Biologie, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada. Electronic address: Louis-Philippe.Hamel@USherbrooke.ca.
authors.forename: Louis-Philippe
authors.initials: LP
authors.lastname: Hamel
authors.affiliation: Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital, Department of Genetics, Harvard Medical School, Boston, MA 02114, USA.
authors.forename: Jen
authors.initials: J
authors.lastname: Sheen
authors.affiliation: Natural Resources Canada, Canadian Forest Service, Laurentian Forestry Centre, 1055 rue du P.E.P.S., P.O. Box 10380, Stn. Sainte-Foy, QC G1V 4C7, Canada. Electronic address: Armand.Seguin@RNCan-NRCan.gc.ca.
authors.forename: Armand
authors.initials: A
authors.lastname: Séguin
mesh_terms: D023281:Genomics; D011494:Protein Kinases / Q000235:genetics*; D057948:Viridiplantae / Q000201:enzymology*; D017871:Calcium-Calmodulin-Dependent Protein Kinases
chemical_list: D011494:Protein Kinases; D017871:Calcium-Calmodulin-Dependent Protein Kinases
keywords: CDPKs; calcium signaling; evolution; green plant lineages