title: MAGNETIC NANOPARTICLE HYPERTHERMIA IN CANCER TREATMENT.
abstract: The activation of magnetic nanoparticles (mNPs) by an alternating magnetic field (AMF) is currently being explored as technique for targeted therapeutic heating of tumors. Various types of superparamagnetic and ferromagnetic particles, with different coatings and targeting agents, allow for tumor site and type specificity. Magnetic nanoparticle hyperthermia is also being studied as an adjuvant to conventional chemotherapy and radiation therapy. This review provides an introduction to some of the relevant biology and materials science involved in the technical development and current and future use of mNP hyperthermia as clinical cancer therapy.
authors.affiliation: Dartmouth Medical School and the Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA, andrew.j.giustini@dartmouth.edu.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Giustini
authors.affiliation: Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.
authors.forename: Alicia A
authors.initials: AA
authors.lastname: Petryk
authors.affiliation: Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.
authors.forename: Shiraz M
authors.initials: SM
authors.lastname: Cassim
authors.affiliation: Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Tate
authors.affiliation: Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.
authors.forename: Ian
authors.initials: I
authors.lastname: Baker
authors.affiliation: Dartmouth Medical School and the Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.
authors.forename: P Jack
authors.initials: PJ
authors.lastname: Hoopes
keywords: Magnetic nanoparticle; cancer; hyperthermia; tumor