title: Probiotics and liver disease.
abstract: Intestinal microbiota play an important role in health and disease. The gut-liver axis provides for an interaction between bacterial components like lipopolysaccharide and hepatic receptors (Toll-like receptors). Dysbiosis and altered intestinal permeability may modulate this interaction and therefore result in hepatic disorders or worsening of hepatic disorders. Administration of health-promoting microbial strains may help ameliorate these harmful interactions and hepatic disorders. This review focuses on changes in gut microbiota in the context of liver disease and possible roles of probiotics, prebiotics, and synbiotics in liver disease.
authors.affiliation: Senior Research Associate at the Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. docvishalsharma@gmail.com.
authors.forename: Vishal
authors.initials: V
authors.lastname: Sharma
authors.affiliation: Internist at Sinai Hospital in Baltimore, MD. shashgarg87@gmail.com.
authors.forename: Shashank
authors.initials: S
authors.lastname: Garg
authors.affiliation: Internist at the Western Michigan University School of Medicine in Kalamazoo. drsourabh79@gmail.com.
authors.forename: Sourabh
authors.initials: S
authors.lastname: Aggarwal
mesh_terms: D001419:Bacteria; D064806:Dysbiosis / Q000150:complications; D041981:Gastrointestinal Tract / Q000382:microbiology*; D006801:Humans; D007422:Intestines; D008099:Liver; D008107:Liver Diseases / Q000188:drug therapy* / Q000209:etiology; D056692:Prebiotics; D019936:Probiotics / Q000627:therapeutic use*; D058616:Synbiotics
chemical_list: D056692:Prebiotics