title: Assessment of buccal aerosolized midazolam for pediatric conscious sedation.
abstract: OBJECTIVE
  To assess the acceptance and efficacy of aerosolized midazolam through buccal mucosa for conscious sedation.
  
  
  METHODS
  Thirty-five children aged 2-6 years with Grade I and II Frankl behavior rating scale were selected for various dental procedures under local anesthesia. Initially behavior-shaping procedures were used and Houpt behavior scoring was recorded. Thereafter, midazolam was administered using a spray through buccal mucosa and scores for acceptance of drug and behavior after sedation were recorded. The data were compiled and a Wilcoxon signed ranks test was used to assess the difference in behavior before and after the sedation.
  
  
  RESULTS
  Eighty-three percent of the patients accepted the drug without any complaint. A statistically significant improvement was seen in the Houpt scores before and after drug administration (P < 0.001).
  
  
  CONCLUSIONS
  Buccal aerosolized midazolam can be used successfully for pediatric conscious sedation.
authors.affiliation: Department of Pedodontics and Preventive Dentistry, SGT Dental College and Research Institute, Gurgaon, Haryana, India.
authors.forename: Radhika
authors.initials: R
authors.lastname: Chopra
authors.forename: Mohita
authors.initials: M
authors.lastname: Marwaha
mesh_terms: D000278:Administration, Buccal; D000336:Aerosols; D000766:Anesthesia, Dental / Q000379:methods*; D000772:Anesthesia, Local / Q000379:methods; D001794:Blood Pressure / Q000502:physiology; D002648:Child; D002652:Child Behavior / Q000187:drug effects; D002675:Child, Preschool; D016292:Procedural Sedation / Q000379:methods*; D003299:Cooperative Behavior; D003448:Crying / Q000502:physiology; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D008874:Midazolam / Q000008:administration & dosage*; D009043:Motor Activity / Q000187:drug effects; D010100:Oxygen / Q000097:blood; D012894:Sleep Stages / Q000187:drug effects
chemical_list: D000336:Aerosols; D006993:Hypnotics and Sedatives; D008874:Midazolam; D010100:Oxygen
keywords: buccal midazolam; conscious sedation; pediatric dentistry