title: Dietary intake and nutritional status of HIV-1-infected children and adolescents in Florianopolis, Brazil.
abstract: This cross-sectional study aimed to investigate the nutritional status and dietary intake of HIV-infected children and adolescents and the relationship between nutritional status and dietary intake and CD4(+) T-cell count and viral load. The sample was composed of 49 subjects aged 7-17 years and living in Florianópolis, Brazil. Nutritional status was assessed by height-for-age and body mass index-for-age. Dietary intake was assessed by a food frequency questionnaire. Spearman correlations and multiple linear regressions were used to determine the relationship between energy, nutrient intake and body mass index-for-age and CD4(+) T-cell count and viral load. The mean body mass index-for-age and height-for-age values were -0.26 ± 0.86 and -0.56 ± 0.92, respectively. The energy intake was 50.8% above the estimated energy requirement and inadequate intake of polyunsaturated fat, cholesterol, fibre, calcium and vitamin C was present in 100%, 57.1%, 40.8%, 61.2% and 26.5% of the sample, respectively. Multiple linear regression analyses revealed that energy intake was correlated with CD4+ T-cell count (r = 0.33; p = 0.028) and viral load (r = -0.35; p = 0.019). These data showed low body mass index-for-age and height-for-age z-scores, high energy intake and inadequate intake of important nutrients for immune function, growth and control of chronic diseases. A lower energy intake was correlated with viral suppression and immune preservation.
authors.affiliation: Department of Nutrition, Federal University of Santa Catarina, Florianópolis, Brazil.
authors.forename: Elaine
authors.initials: E
authors.lastname: Hillesheim
authors.forename: Luiz R A
authors.initials: LR
authors.lastname: Lima
authors.forename: Rosane C R
authors.initials: RC
authors.lastname: Silva
authors.forename: Erasmo B S M
authors.initials: EB
authors.lastname: Trindade
mesh_terms: D000293:Adolescent; D001823:Body Composition; D001827:Body Height; D015992:Body Mass Index; D001938:Brazil; D018791:CD4 Lymphocyte Count; D002648:Child; D003430:Cross-Sectional Studies; D004032:Diet; D002149:Energy Intake; D005247:Feeding Behavior; D005260:Female; D015658:HIV Infections / Q000503:physiopathology* / Q000821:virology; D015497:HIV-1 / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D007407:Interviews as Topic; D016015:Logistic Models; D008297:Male; D044342:Malnutrition / Q000150:complications; D009752:Nutritional Status; D012367:RNA, Viral / Q000032:analysis; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D019562:Viral Load
chemical_list: D012367:RNA, Viral
keywords: AIDS; HIV; adolescent; child; diet; malnutrition; nutritional status