title: Systematic investigations of different cytosine modifications on CpG dinucleotide sequences: the effects on the B-Z transition.
abstract: We have first demonstrated the distinctive effects of three newly reported epigenetic modifications, including 5hmC, 5fC, and 5caC, on B-Z transition of CpG dinucleotide DNAs. We have performed detailed assays and compared their effects. We further studied the regulation of B-Z transition of CpG dinucleotide dodecamers by alternating oxidation and alternating reduction.
authors.affiliation: College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, Wuhan University , Wuhan, Hubei 430072, P. R. China.
authors.forename: Shaoru
authors.initials: S
authors.lastname: Wang
authors.forename: Yuelin
authors.initials: Y
authors.lastname: Long
authors.forename: Jiaqi
authors.initials: J
authors.lastname: Wang
authors.forename: Yushu
authors.initials: Y
authors.lastname: Ge
authors.forename: Pu
authors.initials: P
authors.lastname: Guo
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.forename: Tian
authors.initials: T
authors.lastname: Tian
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhou
mesh_terms: D002942:Circular Dichroism; D003596:Cytosine / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D015226:Dinucleoside Phosphates / Q000737:chemistry*; D057890:Epigenomics; D006801:Humans; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D003596:Cytosine; D004247:DNA; D015226:Dinucleoside Phosphates; C015772:CpG dinucleotide