title: Two new flavanonols from the bark of Akschindlium godefroyanum.
abstract: The first phytochemical investigation of the bark of Akschindlium godefroyanum (Kuntze) H. Ohashi (Fabaceae), a Thai herbal medicine, resulted in the isolation of two new flavanonols, 7,3',5'-trihydroxy-5-methoxyflavanonol (1) and 7,4'-dihydroxy-5,3'-dimethoxyflavanonol (2), and eight known compounds comprising one flavonol, geraldol (3); three flavanonols, (+)-taxifolin (4), (+)-fustin (5) and aromadendrin 5-methyl ether (6); one catechin, (-)-epigallocatechin (7); one triterpenoid, lupeol (8); one steroid, stigmasterol (9) and one steroid glycoside, stigmasterol-3-O-β-d-glucoside (10). Their structures were identified by spectroscopic methods.
authors.affiliation: a Faculty of Science, Khon Kaen University , Khon Kaen 40002 , Thailand.
authors.forename: Nattapong
authors.initials: N
authors.lastname: Chaipukdee
authors.forename: Somdej
authors.initials: S
authors.lastname: Kanokmedhakul
authors.forename: Ratsami
authors.initials: R
authors.lastname: Lekphrom
authors.forename: Kwanjai
authors.initials: K
authors.lastname: Kanokmedhakul
mesh_terms: D007887:Fabaceae / Q000737:chemistry*; D005419:Flavonoids; D044948:Flavonols / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D053978:Pentacyclic Triterpenes / Q000737:chemistry / Q000302:isolation & purification; D024301:Plant Bark / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013265:Stigmasterol / Q000737:chemistry / Q000302:isolation & purification; D013785:Thailand; D000094042:Lupanes
chemical_list: D005419:Flavonoids; D044948:Flavonols; D005960:Glucosides; D006027:Glycosides; D053978:Pentacyclic Triterpenes; D013265:Stigmasterol; C000591060:7,3',5'-trihydroxy-5-methoxyflavanonol; C000591061:7,4'-dihydroxy-5,3'-dimethoxyflavanonol; C522894:fustin; C080220:aromadedrin; C010480:lupeol; D000094042:Lupanes