title: Optical performance of hydrophobic acrylic intraocular lenses with surface light scattering.
abstract: OBJECTIVE
  To evaluate the potential effect of surface light scattering on the optical performance of hydrophobic acrylic intraocular lenses (IOLs) made of Acrysof material.
  
  
  METHODS
  Alcon Laboratories, Inc., Fort Worth, Texas, USA.
  
  
  METHODS
  Experimental study.
  
  
  METHODS
  Explanted IOLs from cadaver eyes with more than 50 computer-compatible tape (CCT) units of scatter were selected, yielding 7 IOLs. Clinically explanted IOLs (n = 4) were obtained after IOLs had been implanted 8.5 to 10.5 years. Explanted IOLs were matched to unused control IOLs. After proteins were removed, scatter was measured for IOLs dry, wetted (2 minutes in a balanced salt solution), and hydrated (24 hours). Badal imaging, ultraviolet-visible transmission, and modulation transfer function (MTF) measurements were performed with hydrated IOLs.
  
  
  RESULTS
  Hydrated scatter values ranged from 80 to 221 CCT for explanted IOLs and 2 to 7 CCT for controls. No differences in Badal image resolution were observed between explanted IOLs and controls. The mean MTF values at 100 line pairs per mm (representing 20/20 visual acuity) were similar between explanted IOLs and controls. Over the range of 400 to 700 nm, a small reduction (mean 2.1% ± 1.4% [SD]) in transmission was observed.
  
  
  CONCLUSIONS
  Surface light scattering of explanted IOLs did not affect image resolution or MTF values. Although light transmission was slightly decreased, the magnitude appeared to be inconsequential for optical performance.
authors.affiliation: From the Department of Ophthalmology and Visual Science (Ogura), Nagoya City University Graduate School of Medicine, Nagoya, Aichi, Japan; Alcon Laboratories, Inc. (Ong, Akinay, Carson, Pei, Karakelle), Fort Worth, Texas, USA.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Ogura
authors.affiliation: From the Department of Ophthalmology and Visual Science (Ogura), Nagoya City University Graduate School of Medicine, Nagoya, Aichi, Japan; Alcon Laboratories, Inc. (Ong, Akinay, Carson, Pei, Karakelle), Fort Worth, Texas, USA. Electronic address: marcia.ong@alconlabs.com.
authors.forename: Marcia D
authors.initials: MD
authors.lastname: Ong
authors.affiliation: From the Department of Ophthalmology and Visual Science (Ogura), Nagoya City University Graduate School of Medicine, Nagoya, Aichi, Japan; Alcon Laboratories, Inc. (Ong, Akinay, Carson, Pei, Karakelle), Fort Worth, Texas, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Akinay
authors.affiliation: From the Department of Ophthalmology and Visual Science (Ogura), Nagoya City University Graduate School of Medicine, Nagoya, Aichi, Japan; Alcon Laboratories, Inc. (Ong, Akinay, Carson, Pei, Karakelle), Fort Worth, Texas, USA.
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Carson
authors.affiliation: From the Department of Ophthalmology and Visual Science (Ogura), Nagoya City University Graduate School of Medicine, Nagoya, Aichi, Japan; Alcon Laboratories, Inc. (Ong, Akinay, Carson, Pei, Karakelle), Fort Worth, Texas, USA.
authors.forename: Ron
authors.initials: R
authors.lastname: Pei
authors.affiliation: From the Department of Ophthalmology and Visual Science (Ogura), Nagoya City University Graduate School of Medicine, Nagoya, Aichi, Japan; Alcon Laboratories, Inc. (Ong, Akinay, Carson, Pei, Karakelle), Fort Worth, Texas, USA.
authors.forename: Mutlu
authors.initials: M
authors.lastname: Karakelle
mesh_terms: D000180:Acrylic Resins; D001672:Biocompatible Materials; D020878:Device Removal; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007910:Lenses, Intraocular; D008027:Light; D055095:Optics and Photonics; D012086:Reoperation; D012542:Scattering, Radiation; D014786:Vision Disorders / Q000601:surgery
chemical_list: D000180:Acrylic Resins; D001672:Biocompatible Materials