title: Misalignment of a novel single-piece acrylic intraocular lens in the first three months after surgery.
abstract: OBJECTIVE
  To evaluate the misalignment of a new single-piece microincisional hydrophobic acrylic intraocular lens (IOL) in emmetropic, myopic and hyperopic eyes within the first 3 months after surgery.
  
  
  METHODS
  Vienna Institute for Research in Ocular Surgery, Karl Landsteiner Institute, Hanusch Hospital, Department of Ophthalmology, Vienna, Austria.
  
  
  METHODS
  Patients with age-related cataract were included in this prospective study. Each patient received a single-piece microincisional hydrophobic acrylic IOL (AF-1 NY-60, Hoya) in the study eye. Subgroups of emmetropic, myopic and hyperopic eyes were defined according to IOL power calculation. Anterior chamber depth (ACD) measurements were performed with an AC-Master. Tilt and decentration of the IOL were measured with a Purkinje meter. Follow-up assessments were performed 1 h, 3 weeks and 3 months after surgery.
  
  
  RESULTS
  Forty-two eyes of 42 patients (21 emmetropic, 10 myopic and 11 hyperopic eyes) were included. The mean ACD 1 h, 3 weeks and 3 months after surgery was 4.597 ± 0.533, 4.483 ± 0.347 and 4.438 ± 0.398 mm, respectively. Differences in ACD between follow-ups and between subgroups were not statistically significant (both p > 0.05). On average, 3 months after surgery IOLs were tilted 0.81 ± 2.86° nasally and 0.70 ± 3.13° inferiorly and decentered 0.06 ± 0.24 mm nasally and 0.15 ± 0.29 mm superiorly. Differences in tilt and decentration were not statistically significant (both p > 0.05). We observed 1 case of severe capsular fibrosis.
  
  
  CONCLUSIONS
  The single-piece microincisional hydrophobic acrylic IOL showed good axial stability and only little, clinically not relevant tilt and decentration in the first 3 months after surgery.
authors.affiliation: Vienna Institute for Research in Ocular Surgery, Karl Landsteiner Institute, Department of Ophthalmology, Hanusch Hospital, Vienna, Austria.
authors.forename: Yen-An
authors.initials: YA
authors.lastname: Chen
authors.forename: Nino
authors.initials: N
authors.lastname: Hirnschall
authors.forename: Sophie
authors.initials: S
authors.lastname: Maedel
authors.forename: Oliver
authors.initials: O
authors.lastname: Findl
mesh_terms: D000180:Acrylic Resins; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000473:pathology; D060437:Artificial Lens Implant Migration / Q000175:diagnosis / Q000209:etiology*; D058453:Emmetropia / Q000502:physiology; D005260:Female; D006801:Humans; D006956:Hyperopia / Q000150:complications / Q000601:surgery; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications / Q000601:surgery; D018918:Phacoemulsification; D011183:Postoperative Complications; D011446:Prospective Studies
chemical_list: D000180:Acrylic Resins