title: Optimized ultrasound-assisted extraction of phenolic compounds from Polygonum cuspidatum.
abstract: In this study the phenolic compounds piceid, resveratrol and emodin were extracted from P. cuspidatum roots using ultrasound-assisted extraction. Multiple response surface methodology was used to optimize the extraction conditions of these phenolic compounds. A three-factor and three-level Box-Behnken experimental design was employed to evaluate the effects of the operation parameters, including extraction temperature (30-70 °C), ethanol concentration (40%-80%), and ultrasonic power (90-150 W), on the extraction yields of piceid, resveratrol, and emodin. The statistical models built from multiple response surface methodology were developed for the estimation of the extraction yields of multi-phenolic components. Based on the model, the extraction yields of piceid, resveratrol, and emodin can be improved by controlling the extraction parameters. Under the optimum conditions, the extraction yields of piceid, resveratrol and emodin were 10.77 mg/g, 3.82 mg/g and 11.72 mg/g, respectively.
authors.forename: Chia-Hung
authors.initials: CH
authors.lastname: Kuo
authors.forename: Bao-Yuan
authors.initials: BY
authors.lastname: Chen
authors.forename: Yung-Chuan
authors.initials: YC
authors.lastname: Liu
authors.forename: Chieh-Ming J
authors.initials: CM
authors.lastname: Chang
authors.forename: Tzu-Shing
authors.initials: TS
authors.lastname: Deng
authors.affiliation: College of Tea and Food Science, Wuyi University, Fujian 354300, China. jhchen@dragon.nchu.edu.tw.
authors.forename: Jiann-Hwa
authors.initials: JH
authors.lastname: Chen
authors.affiliation: College of Tea and Food Science, Wuyi University, Fujian 354300, China. cjshieh@dragon.nchu.edu.tw.
authors.forename: Chwen-Jen
authors.initials: CJ
authors.lastname: Shieh
mesh_terms: D004642:Emodin / Q000737:chemistry / Q000302:isolation & purification; D045468:Fallopia japonica / Q000737:chemistry; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification*; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D000077185:Resveratrol; D012997:Solvents / Q000737:chemistry; D013016:Sound; D013267:Stilbenes / Q000737:chemistry / Q000302:isolation & purification; D013696:Temperature
chemical_list: D005960:Glucosides; D010636:Phenols; D010936:Plant Extracts; D012997:Solvents; D013267:Stilbenes; D004642:Emodin; D000077185:Resveratrol; C058229:polydatin