title: Porous platinum nanotubes modified with dendrimers as nanocarriers and electrocatalysts for sensitive electrochemical aptasensors based on enzymatic signal amplification.
abstract: A highly sensitive electrochemical aptasensor for thrombin detection is developed and demonstrated by using porous platinum nanotubes modified with polyamidoamine dendrimers as nanocarriers and electrocatalysts. The proposed strategy affords a low detection limit of 0.03 pM based on enzyme-based signal amplification.
authors.affiliation: Chongqing Key Laboratory of Analytical Chemistry, Education Ministry Key Laboratory on Luminescence and Real-Time Analysis, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. xwju@swu.edu.cn.
authors.forename: Wenju
authors.initials: W
authors.lastname: Xu
authors.forename: Yongmei
authors.initials: Y
authors.lastname: Wu
authors.forename: Huayu
authors.initials: H
authors.lastname: Yi
authors.forename: Lijuan
authors.initials: L
authors.lastname: Bai
authors.forename: Yaqin
authors.initials: Y
authors.lastname: Chai
authors.forename: Ruo
authors.initials: R
authors.lastname: Yuan
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation; D050091:Dendrimers / Q000737:chemistry*; D055664:Electrochemical Techniques / Q000295:instrumentation*; D057230:Limit of Detection; D043942:Nanotubes / Q000737:chemistry*; D010984:Platinum / Q000737:chemistry*; D011073:Polyamines / Q000737:chemistry; D016062:Porosity; D015203:Reproducibility of Results; D012815:Signal Processing, Computer-Assisted
chemical_list: D050091:Dendrimers; C531249:Poly(amidoamine); D011073:Polyamines; D010984:Platinum