title: Iatrogenic neurology.
abstract: Iatrogenic disease is one of the most frequent causes of hospital admissions and constitutes a growing public health problem. The most common type of iatrogenic neurologic disease is pharmacologic, and the central and peripheral nervous systems are particularly vulnerable. Despite this, iatrogenic disease is generally overlooked as a differential diagnosis among neurologic patients. The clinical picture of pharmacologically mediated iatrogenic neurologic disease can range from mild to fatal. Common and uncommon forms of drug toxicity are comprehensively addressed in this chapter. While the majority of neurologic adverse effects are listed and referenced in the tables, the most relevant issues are further discussed in the text.
authors.affiliation: Department of Clinical Neurological Sciences, London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada.
authors.forename: Luciano A
authors.initials: LA
authors.lastname: Sposato
authors.affiliation: INEBA Institute of Neurosciences, Buenos Aires, Argentina; Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina. Electronic address: fusti@fibertel.com.ar.
authors.forename: Osvaldo
authors.initials: O
authors.lastname: Fustinoni
mesh_terms: D000890:Anti-Infective Agents / Q000009:adverse effects; D000927:Anticonvulsants / Q000009:adverse effects; D000928:Antidepressive Agents / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects; D000978:Antiparkinson Agents / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000009:adverse effects; D002317:Cardiovascular Agents / Q000009:adverse effects; D000697:Central Nervous System Stimulants / Q000009:adverse effects; D005343:Fibrinolytic Agents / Q000009:adverse effects; D006728:Hormones / Q000009:adverse effects; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects; D007049:Iatrogenic Disease; D009422:Nervous System Diseases / Q000139:chemically induced / Q000209:etiology* / Q000628:therapy; D018697:Nootropic Agents / Q000009:adverse effects; D010276:Parasympatholytics / Q000009:adverse effects
chemical_list: D000890:Anti-Infective Agents; D000927:Anticonvulsants; D000928:Antidepressive Agents; D000970:Antineoplastic Agents; D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D002317:Cardiovascular Agents; D000697:Central Nervous System Stimulants; D005343:Fibrinolytic Agents; D006728:Hormones; D006993:Hypnotics and Sedatives; D018697:Nootropic Agents; D010276:Parasympatholytics
keywords: Iatrogenic neurology; drug toxicity; drugs and brain; neurologic toxicity; neurological adverse effects; neurotoxic complications; neurotoxic effects; neurotoxicity; toxic complications