title: Allogeneic hematopoietic stem cell transplantation in mycosis fungoides.
abstract: Mycosis Fungoides is typically an indolent disease in early stages. However, approximately 30% of patients have advanced staged disease at presentation and 20% will develop it at some time. These patients have a poorer prognosis with a median survival of 2-4 years. The only curative option for mycosis fungoides may be hematopoietic allogeneic stem cell transplantation. We report the case of a patient with mycosis fungoides in an advanced stage (IIB), refractory to treatment options. She underwent allogeneic hematopoietic stem-cell transplantation (allo-HSCT). The patient remains in complete remission nineteen months after allo-HSCT. Allogeneic transplantation can alter the natural history of mycosis fungoides and should be considered in patients who have refractory disease or short-lived responses with standard therapies.
authors.affiliation: Federal University of Rio de Janeiro.
authors.forename: Angelo
authors.initials: A
authors.lastname: Atalla
authors.affiliation: Universidade de São Paulo.
authors.forename: Abrahão Elias
authors.initials: AE
authors.lastname: Hallack Neto
authors.affiliation: Hospital Maternidade Therezinha de Jesus.
authors.forename: Denise Bittencourt
authors.initials: DB
authors.lastname: Siqueira
authors.affiliation: Hospital Maternidade Therezinha de Jesus.
authors.forename: Gabriela Cumani
authors.initials: GC
authors.lastname: Toledo
mesh_terms: D000328:Adult; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006801:Humans; D009182:Mycosis Fungoides / Q000473:pathology / Q000601:surgery*; D012074:Remission Induction; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D014184:Transplantation, Homologous; D016896:Treatment Outcome