title: Microcapsule mechanics: from stability to function.
abstract: Microcapsules are reviewed with special emphasis on the relevance of controlled mechanical properties for functional aspects. At first, assembly strategies are presented that allow control over the decisive geometrical parameters, diameter and wall thickness, which both influence the capsule's mechanical performance. As one of the most powerful approaches the layer-by-layer technique is identified. Subsequently, ensemble and, in particular, single-capsule deformation techniques are discussed. The latter generally provide more in-depth information and cover the complete range of applicable forces from smaller than pN to N. In a theory chapter, we illustrate the physics of capsule deformation. The main focus is on thin shell theory, which provides a useful approximation for many deformation scenarios. Finally, we give an overview of applications and future perspectives where the specific design of mechanical properties turns microcapsules into (multi-)functional devices, enriching especially life sciences and material sciences.
authors.affiliation: University of Bayreuth, Department of Physical Chemistry II, Universitätsstraße 30, 95440 Bayreuth, Germany.
authors.forename: Martin P
authors.initials: MP
authors.lastname: Neubauer
authors.affiliation: University of Bayreuth, Department of Physical Chemistry II, Universitätsstraße 30, 95440 Bayreuth, Germany.
authors.forename: Melanie
authors.initials: M
authors.lastname: Poehlmann
authors.affiliation: University of Bayreuth, Department of Physical Chemistry II, Universitätsstraße 30, 95440 Bayreuth, Germany. Electronic address: Andreas.Fery@uni-bayreuth.de.
authors.forename: Andreas
authors.initials: A
authors.lastname: Fery
mesh_terms: D002214:Capsules / Q000737:chemistry*; D055598:Chemical Phenomena; D004339:Drug Compounding / Q000639:trends; D016503:Drug Delivery Systems; D055595:Mechanical Phenomena; D008956:Models, Chemical; D053769:Nanocapsules / Q000737:chemistry; D036103:Nanotechnology / Q000639:trends
chemical_list: D002214:Capsules; D053769:Nanocapsules
keywords: Drug delivery; Layer-by-layer; Mechanical characterization; Microcapsules; Shell theory