title: Predictors of postpartum depression: prospective study of 264 women followed during pregnancy and postpartum.
abstract: The prevalence of postpartum depression is approximately 13%. Postpartum depression is associated with a higher maternal morbidity and mortality, and also with pervasive effects on the emotional, cognitive and behavioral development of the child. The aim of our study was to identify socio-demographic, psychosocial and obstetrical risk factors of postpartum depression in a middle class community sample, using a prospective design. We enrolled consecutively 312 pregnant outpatients in a single maternity unit. The first assessment was conducted between 32 and 41 weeks gestation, and a second time between 6 and 8 weeks after delivery. Depressive symptoms were measured using the French version of the Edinburgh Postnatal Depression Scale (EPDS). A cut-off score of 12/30 or above was considered as indicative of Major Depression. Of the initial sample of 312 women, 264 (84.6%) were followed-up between 6 and 8 weeks after delivery and considered for analysis. Depression during pregnancy, migrant status, and physical abuse by the partner were independently associated with postpartum depression when considered together, whereas physical complications were significantly associated with postpartum depression only when adjusting for antenatal depression. Depression during pregnancy, history of physical abuse, migrant status and postpartum physical complications are four major risk factors for postpartum depression.
authors.affiliation: Assistance Publique-Hôpitaux de Paris, Hôpital Louis Mourier, Psychiatry Department, Colombes, France; Université Paris Diderot, Sorbonne Paris Cité, Faculté de médecine, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Faculté de médecine, Paris, France; Service Hospitalo-Universitaire, Centre Hospitalier Sainte Anne, Paris, France.
authors.forename: Adeline
authors.initials: A
authors.lastname: Gaillard
authors.affiliation: Assistance Publique-Hôpitaux de Paris, Hôpital Louis Mourier, Psychiatry Department, Colombes, France; Université Paris Diderot, Sorbonne Paris Cité, Faculté de médecine, Paris, France; INSERM U894, Centre Psychiatrie et Neurosciences, Paris, France.
authors.forename: Yann
authors.initials: Y
authors.lastname: Le Strat
authors.affiliation: Université Paris Diderot, Sorbonne Paris Cité, Faculté de médecine, Paris, France; Assistance Publique-Hôpitaux de Paris, Hôpital Louis Mourier, Gynecology and Obstetrics Departments, Colombes, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Mandelbrot
authors.affiliation: Université Paris Diderot, Sorbonne Paris Cité, Faculté de médecine, Paris, France; Assistance Publique-Hôpitaux de Paris, Hôpital Louis Mourier, Anesthesiology Department, Colombes, France.
authors.forename: Hawa
authors.initials: H
authors.lastname: Keïta
authors.affiliation: Assistance Publique-Hôpitaux de Paris, Hôpital Louis Mourier, Psychiatry Department, Colombes, France; Université Paris Diderot, Sorbonne Paris Cité, Faculté de médecine, Paris, France; INSERM U894, Centre Psychiatrie et Neurosciences, Paris, France. Electronic address: caroline.dubertret@lmr.aphp.fr.
authors.forename: Caroline
authors.initials: C
authors.lastname: Dubertret
mesh_terms: D000293:Adolescent; D000328:Adult; D019052:Depression, Postpartum / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D006801:Humans; D049590:Postpartum Period / Q000523:psychology*; D011237:Predictive Value of Tests; D011247:Pregnancy; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D055815:Young Adult
keywords: EPDS; Postpartum depression; Prospective study; Risk factors