title: Antiinflammatory and antioxidant flavonoids from Helichrysum kraussii and H. odoratissimum flowers.
abstract: Organic extracts of the flowers of Helichrysum kraussii and H. odoratissimum contain several bioactive flavonoids, characterized by 'H NMR, '3C NMR and mass spectrometry. Four flavonoids, 5,6-dihydroxy-3,7,8-trimethoxyflavone, 5,7-dihydroxy-3-methoxyflavone, 3',4',5,7-tetrahydroxy-3-methoxyflavone and 3',4',3,5-tetrahydroxy-7-methoxyflavone, have antioxidant activity by the DPPH free radical assay, while 5,6-dihydroxy-3,7,8-trimethoxyflavone and 3',4',3,5-tetrahydroxy-7-methoxyflavone have promising anti-inflammatory activity.
authors.affiliation: Medicines Control Council, Andries Street, Pretoria, 0001, South Africa.
authors.forename: Percival B
authors.initials: PB
authors.lastname: Legoalea
authors.affiliation: Department of Science and Technology, Pretoria, 0001, South Africa.
authors.forename: Mahlori J
authors.initials: MJ
authors.lastname: Mashimbyeb
authors.affiliation: Department of Chemistry, University of Venda, Private Bag X5050, Thohoyandou, 0950, South Africa.
authors.forename: Teunis
authors.initials: T
authors.lastname: van Rec
mesh_terms: D000893:Anti-Inflammatory Agents / Q000302:isolation & purification*; D000975:Antioxidants / Q000302:isolation & purification*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D035264:Flowers / Q000737:chemistry; D036562:Helichrysum / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D005419:Flavonoids