title: MALDI Imaging Mass Spectrometry-A Mini Review of Methods and Recent Developments.
abstract: As the only imaging method available, Imaging Mass Spectrometry (IMS) can determine both the identity and the distribution of hundreds of molecules on tissue sections, all in one single run. IMS is becoming an established research technology, and due to recent technical and methodological improvements the interest in this technology is increasing steadily and within a wide range of scientific fields. Of the different IMS methods available, matrix-assisted laser desorption/ionization (MALDI) IMS is the most commonly employed. The course at IMSC 2012 in Kyoto covered the fundamental principles and techniques of MALDI-IMS, assuming no previous experience in IMS. This mini review summarizes the content of the one-day course and describes some of the most recent work performed within this research field.
authors.affiliation: Department of Cell Biology and Anatomy, Hamamatsu University School of Medicine ; Medical Mass Spectrometry, Department of Pharmaceutical Biosciences, Uppsala University.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Eriksson
authors.affiliation: Department of Cell Biology and Anatomy, Hamamatsu University School of Medicine.
authors.forename: Noritaka
authors.initials: N
authors.lastname: Masaki
authors.affiliation: Department of Medical Chemistry, Kansai Medical University.
authors.forename: Ikuko
authors.initials: I
authors.lastname: Yao
authors.affiliation: Department of Cell Biology and Anatomy, Hamamatsu University School of Medicine.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Hayasaka
authors.affiliation: Department of Cell Biology and Anatomy, Hamamatsu University School of Medicine.
authors.forename: Mitsutoshi
authors.initials: M
authors.lastname: Setou
keywords: Imaging Mass Spectrometry; MALDI IMS; heat stabilization; sample preparation