title: Incidence of primary skin cancer after organ transplantation: An 18-year single-center experience in Korea.
abstract: BACKGROUND
  Skin cancer is the most common malignancy to arise after organ transplantation in Caucasians, but limited data are available on its incidence in Asian transplant recipients.
  
  
  OBJECTIVE
  We sought to assess the incidence of skin cancer after organ transplantation in a Korean cohort.
  
  
  METHODS
  A cohort study was conducted to determine the incidence and risk factors for skin cancers among kidney, liver, heart, or pancreas transplant recipients, treated at the Asan Medical Center in Seoul, Korea.
  
  
  RESULTS
  The cumulative incidences of skin cancer were 0.70% at 5 years, 1.66% at 10 years, and 2.31% at 15 years. For all skin cancers, squamous cell carcinoma, basal cell carcinoma, and Kaposi sarcoma, the standardized incidence ratios between the recipients and the Korean general population were 30.9 (95% confidence interval, 12.4-63.6), 61.9 (12.8-180.8), 11.9 (0.3-66.1), and 565.2 (68.4-2041.6) after the end of the fifth posttransplantation year, respectively.
  
  
  CONCLUSIONS
  We cannot exclude the possibility of both the underestimation because of potential missing cases and the overestimation because of the ascertainment bias.
  
  
  CONCLUSIONS
  The incidence of posttransplantation skin cancer is very low in Korean patients. However, the risk of skin cancer in organ transplant recipients may be considerably higher than that in the Korean general population.
authors.affiliation: Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Gyeong-Hun
authors.initials: GH
authors.lastname: Park
authors.affiliation: Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Sung Eun
authors.initials: SE
authors.lastname: Chang
authors.affiliation: Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Chong Hyun
authors.initials: CH
authors.lastname: Won
authors.affiliation: Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. Electronic address: miumiu@amc.seoul.kr.
authors.forename: Mi Woo
authors.initials: MW
authors.lastname: Lee
authors.affiliation: Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Jee Ho
authors.initials: JH
authors.lastname: Choi
authors.affiliation: Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Kee Chan
authors.initials: KC
authors.lastname: Moon
authors.affiliation: Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Duck Jong
authors.initials: DJ
authors.lastname: Han
authors.affiliation: Department of Nephrology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Su Kil
authors.initials: SK
authors.lastname: Park
authors.affiliation: Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Jae-Joong
authors.initials: JJ
authors.lastname: Kim
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Jae Won
authors.initials: JW
authors.lastname: Lee
authors.affiliation: Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Sung-Gyu
authors.initials: SG
authors.lastname: Lee
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D044466:Asian People / Q000706:statistics & numerical data; D002280:Basal Cell Carcinoma / Q000208:ethnology / Q000209:etiology / Q000503:physiopathology; D002294:Carcinoma, Squamous Cell / Q000208:ethnology / Q000209:etiology / Q000503:physiopathology; D016208:Databases, Factual; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation / Q000009:adverse effects* / Q000379:methods; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D018570:Risk Assessment; D012514:Sarcoma, Kaposi / Q000208:ethnology / Q000209:etiology / Q000503:physiopathology; D017678:Sex Distribution; D012878:Skin Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology*; D014019:Tissue Donors; D055815:Young Adult
keywords: Asian; Korean; immunosuppression; incidence; skin cancer; transplantation