title: Anaphylactic shock after amiodarone infusion resulting in haemodynamic collapse requiring a temporary ventricular assist device.
abstract: Acute heart failure related to anaphylactic shock is often reversible and necessitates aggressive support to ensure full recovery. We report the case of a 15-year-old boy who developed severe ventricular dysfunction and haemodynamic instability after administration of amiodarone and required temporary mechanical circulatory support with a left ventricular assist device. He had full recovery of cardiac function and returned to baseline neurologic status. This is the first report of successful left ventricular assist device use for recovery from cardiovascular collapse due to anaphylaxis.
authors.affiliation: Cincinnati Children's Hospital Medical Center,The Heart Institute,Cincinnati,Ohio,United States of America.
authors.forename: Konstantin
authors.initials: K
authors.lastname: Averin
authors.affiliation: Cincinnati Children's Hospital Medical Center,The Heart Institute,Cincinnati,Ohio,United States of America.
authors.forename: Angela
authors.initials: A
authors.lastname: Lorts
authors.affiliation: Cincinnati Children's Hospital Medical Center,The Heart Institute,Cincinnati,Ohio,United States of America.
authors.forename: Chad
authors.initials: C
authors.lastname: Connor
mesh_terms: D000293:Adolescent; D000638:Amiodarone / Q000008:administration & dosage / Q000009:adverse effects*; D000707:Anaphylaxis / Q000150:complications* / Q000503:physiopathology; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000009:adverse effects; D006333:Heart Failure / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D006353:Heart-Assist Devices; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D017180:Tachycardia, Ventricular / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D000889:Anti-Arrhythmia Agents; D000638:Amiodarone