title: Preoperative assessment of salivary gland neoplasms with fine needle aspiration cytology and echography: a retrospective analysis of 357 cases.
abstract: Fine-needle aspiration cytology (FNAC) is a minimally invasive procedure usually well tolerated, easy to perform, quick, cheap and easy to repeat in case of doubts or non-diagnostic results. Echography is also a fast, cheap and non-invasive tool; however, the role of FNAC and echography in the diagnosis of salivary gland pathology is not universally recognised. Three hundred and fifty-seven patients with a cytological diagnosis at FNAC, and 247 of these who were also studied with echography, were enrolled for this retrospective study. The final histopathological diagnoses, obtained after surgery, were then compared to the preoperative FNAC diagnoses and echographic findings. From the analysis of our data, the overall FNAC specificity resulted 93 percent, sensitivity 83 percent, and diagnostic accuracy 92 percent. Echography sensibility was 57.1 percent specificity 98.2 percent, while positive and negative predictive value were respectively 80 percent and 94.8 percent. While echography can be useful in order to provide a better characterization of salivary gland lesions, FNAC can then be considered a safe diagnostic tool with reliable sensitivity and specificity for the assessment of salivary gland pathology and thus for selecting patients and indicating the best surgical treatment.
authors.affiliation: ENT Department, University Hospital of Ferrara, Ferrara, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Pastore
authors.affiliation: ENT Department, University Hospital of Ferrara, Ferrara, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Borin
authors.affiliation: ENT Department, University Hospital of Ferrara, Ferrara, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Malagutti
authors.affiliation: ENT Department, University Hospital of Ferrara, Ferrara, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Di Laora
authors.affiliation: ENT Department, University Hospital of Ferrara, Ferrara, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Beccati
authors.affiliation: ENT Department, University Hospital of Ferrara, Ferrara, Italy.
authors.forename: A L
authors.initials: AL
authors.lastname: Delazer
authors.affiliation: ENT Department, University Hospital of Ferrara, Ferrara, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Bianchini
authors.affiliation: ENT Department, University Hospital of Ferrara, Ferrara, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Stomeo
authors.affiliation: ENT Department, University Hospital of Ferrara, Ferrara, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Ciorba
authors.affiliation: ENT Department, University Hospital of Ferrara, Ferrara, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Pelucchi
mesh_terms: D044963:Biopsy, Fine-Needle; D006801:Humans; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000648:ultrastructure; D012469:Salivary Glands / Q000473:pathology*