title: Classic congenital adrenal hyperplasia: A delayed presentation.
abstract: Congenital adrenal hyperplasia (CAH) is a rare congenital disorder, which in cases of female genotype may result in virilization. Specific enzyme deficiencies in adrenocorticoid hormones biosynthetic pathway lead to excess androgen production causing virilization. Classic type presents early in infant life as salt losing or simple virilizing type, whereas non classic form presents late at puberty or in adult life. Depending on the type of classic CAH, type of adrenocorticoid deficiency, extent of virilization & genotype, surgical corrective procedures, glucocorticoid & mineralocorticoid replacement therapy are the mainstay of management. We present here a case of classic congenital adrenal hyperplasia of simple virilizing type, which presented later in childhood.
authors.affiliation: Dr. Saima Aziz Siddiqui, MBBS, MCPS, FCPS, Assistant Professor, Department of Obstetrics & Gynaecology, Dow University of Health Sciences & Civil Hospital Karachi, Karachi, Pakistan.
authors.forename: Saima
authors.initials: S
authors.lastname: Aziz Siddiqui
authors.affiliation: Dr. Nargis Soomro, MBBS, DA, FCPS, FRCOG, Professor, Department of Obstetrics & Gynaecology, Dow University of Health Sciences & Civil Hospital Karachi, Karachi, Pakistan.
authors.forename: Nargis
authors.initials: N
authors.lastname: Soomro
authors.affiliation: Dr. Ashraf Ganatra, MBBS, M.S(Plastic Surgery), Professor, Department of Plastic Surgery, Dow University of Health Sciences & Civil Hospital Karachi, Karachi, Pakistan.
authors.forename: Ashraf
authors.initials: A
authors.lastname: Ganatra
keywords: Ambiguous genitalia; Clitoromegaly; Clitoroplasty; Congenital adrenal hyperplasia; Virilization