title: [Fractionated conformal stereotactic irradiation of recurrent sacral tumour. Case report and first description of the method in Hungary].
abstract: Non-invasive procedures completing traditional surgical treatment play an increasing role in the management of central nervous system malignancies. Conformal stereotactic irradiation (radiosurgery) has become a routine method in intracranial malignancies. However, application of this modality in tumours of the spinal cord and spinal column is much more difficult to perform. It is because extracranial organs can be only inaccurately fixed, and radio-sensitivity of the spinal cord and risks of radionecrosis with ensuing paraplegia are high. A recurrent sacrum chordoma treated by means of this modality - first reported in Hungary - has been chosen for case presentation as the criteria for radiotherapy such as high dose to target volume, minimal dose to neighbouring structures highly sensitive to radiation are best met in these tumours by means of conformal stereotactic radiotherapy. On the basis of further 13 extracranial cases treated with this method one can conclude that high precision stereotactic conformal radiotherapy offers up-grade to traditional radiotherapy despite the fact that it is a time-consuming procedure. The oncological efficiency, the reduced risks of side effects and the improved quality of life due to this treatment modality compensate duly for the increased labour input.
authors.affiliation: Idegsebészeti Klinika, Pécsi Tudományegyetem, Pécs, Hungary. doczi.tamas@pte.hu.
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Horváth
authors.affiliation: Onkoterápiás Intézet, Pécsi Tudományegyetem, Pécs, Hungary.
authors.forename: József
authors.initials: J
authors.lastname: Szávai
authors.affiliation: Onkoterápiás Intézet, Pécsi Tudományegyetem, Pécs, Hungary.
authors.forename: Szabolcs
authors.initials: S
authors.lastname: Bellyei
authors.affiliation: Onkoterápiás Intézet, Pécsi Tudományegyetem, Pécs, Hungary.
authors.forename: Róbert
authors.initials: R
authors.lastname: Farkas
authors.affiliation: Onkoterápiás Intézet, Pécsi Tudományegyetem, Pécs, Hungary.
authors.forename: László
authors.initials: L
authors.lastname: Mangel
authors.affiliation: Onkoterápiás Intézet, Pécsi Tudományegyetem, Pécs, Hungary.
authors.forename: Péter
authors.initials: P
authors.lastname: Kovács
authors.affiliation: Onkoterápiás Intézet, Pécsi Tudományegyetem, Pécs, Hungary.
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Sebestyén
authors.affiliation: Idegsebészeti Klinika, Pécsi Tudományegyetem, Pécs, Hungary. doczi.tamas@pte.hu.
authors.forename: Gábor
authors.initials: G
authors.lastname: Kasó
authors.affiliation: Pathologiai Intézet, Pécsi Tudományegyetem, Pécs, Hungary.
authors.forename: Éva
authors.initials: É
authors.lastname: Gömöri
authors.affiliation: Onkoterápiás Intézet, Pécsi Tudományegyetem, Pécs, Hungary.
authors.forename: Gábor
authors.initials: G
authors.lastname: Horváth
authors.affiliation: Onkoterápiás Intézet, Pécsi Tudományegyetem, Pécs, Hungary.
authors.forename: Olga
authors.initials: O
authors.lastname: Ésik
authors.affiliation: Klinikai Idegtudományi Képalkotó Kutatócsoport, MTA-PTE, Pécs, Hungary.
authors.forename: Tamás
authors.initials: T
authors.lastname: Dóczi
mesh_terms: D019583:Dose Fractionation, Radiation; D005260:Female; D006801:Humans; D006814:Hungary; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D016634:Radiosurgery / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted; D020266:Radiotherapy, Conformal / Q000379:methods*; D012447:Sacrum; D013120:Spinal Cord Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D016896:Treatment Outcome