title: [Management of preterm prelabor rupture of membranes with respect to the inflammatory complications - our experiences].
abstract: OBJECTIVE
  Preterm prelabor rupture of membranes is responsible for approximately one third of all preterm deliveries. The most common complications associated with this pregnancy pathology are microbial invasion of the amniotic cavity, intraamniotic inflammation, intraamniotic infection and histological chorioamnionitis. This article explains these complicatioss and their relation to the optimal management of preterm prelabor rupture of membranes.
  
  
  METHODS
  Overview study.
  
  
  METHODS
  Department of Obstetrics and Gynecology, Charles University in Prague, Faculty of Medicine and University Hospital Hradec Kralove.
  
  
  METHODS
  To analyze current knowledge and our own experiences regarding inflammatory complications of preterm prelabor rupture of membranes.
  
  
  CONCLUSIONS
  Inflammatory complications of preterm prelabor rupture of membranes are associated with risk of development of early onset sepsis. Nevertheless, gestational age is a main confounder affecting neonatal morbidity and mortality.
authors.forename: M
authors.initials: M
authors.lastname: Kacerovský
authors.forename: I
authors.initials: I
authors.lastname: Musilová
mesh_terms: D000653:Amniotic Fluid / Q000382:microbiology; D002821:Chorioamnionitis / Q000628:therapy*; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000209:etiology / Q000628:therapy*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D047928:Premature Birth