title: Estrogens as antioxidant modulators in human fertility.
abstract: Among treatments proposed for idiopathic male infertility, antiestrogens, like tamoxifen, play a possible role. On the other hand, oxidative stress is a mechanism well recognized for deleterious effects on spermatozoa function. After reviewing the literature on the effects of estrogens in modulation of antioxidant systems, in both sexes, and in different in vivo and in vitro models, we suggest, also on the basis of personal data, that a tamoxifen treatment could be active via an increase in seminal antioxidants.
authors.affiliation: Division of Endocrinology, Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Mancini
authors.affiliation: Division of Endocrinology, Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Raimondo
authors.affiliation: Division of Endocrinology, Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Persano
authors.affiliation: Division of Endocrinology, Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Di Segni
authors.affiliation: Division of Endocrinology, Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Cammarano
authors.affiliation: Division of Endocrinology, Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Gadotti
authors.affiliation: Institute of Biochemistry and Clinical Biochemistry, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Silvestrini
authors.affiliation: Division of Endocrinology, Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Pontecorvi
authors.affiliation: Institute of Biochemistry and Clinical Biochemistry, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Meucci