title: MITK-US: real-time ultrasound support within MITK.
abstract: OBJECTIVE
  Intra-procedural acquisition of the patient anatomy is a key technique in the context of computer-assisted interventions (CAI). Ultrasound (US) offers major advantages as an interventional imaging modality because it is real time and low cost and does not expose the patient or physician to harmful radiation. To advance US-related research, the purpose of this paper was to develop and evaluate an open-source framework for US-based CAI applications.
  
  
  METHODS
  We developed the open-source software module MITK-US for acquiring and processing US data as part of the well-known medical imaging interaction toolkit (MITK). To demonstrate its utility, we applied the module to implement a new concept for US-guided needle insertion. Performance of the US module was assessed by determining frame rate and latency for both a simple sample application and a more complex needle guidance system.
  
  
  RESULTS
  MITK-US has successfully been used to implement both sample applications. Modern laptops achieve frame rates above 24 frames per second. Latency is measured to be approximately 250 ms or less.
  
  
  CONCLUSIONS
  MITK-US can be considered a viable rapid prototyping environment for US-based CAI applications.
authors.affiliation: German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 , Heidelberg, Germany, k.maerz@dkfz-heidelberg.de.
authors.forename: K
authors.initials: K
authors.lastname: März
authors.forename: A M
authors.initials: AM
authors.lastname: Franz
authors.forename: A
authors.initials: A
authors.lastname: Seitel
authors.forename: A
authors.initials: A
authors.lastname: Winterstein
authors.forename: R
authors.initials: R
authors.lastname: Bendl
authors.forename: S
authors.initials: S
authors.lastname: Zelzer
authors.forename: M
authors.initials: M
authors.lastname: Nolden
authors.forename: H-P
authors.initials: HP
authors.lastname: Meinzer
authors.forename: L
authors.initials: L
authors.lastname: Maier-Hein
mesh_terms: D004867:Equipment Design; D006801:Humans; D019047:Phantoms, Imaging; D012984:Software; D025321:Surgery, Computer-Assisted / Q000295:instrumentation*; D014463:Ultrasonography / Q000295:instrumentation*