title: Platelet receptors; an instrumental of platelet physiology.
abstract: Platelets play an important role in hemostasis, inflammation, host defense, tumor growth and metastasis. Platelets receptors are instrumental in platelet-platelet aggregation and interaction of platelets with leukocytes, endothelial cells and coagulation factors. These receptors are also the targets for antiplatelet drugs. This review focuses on the role of platelet receptors in human physiology. Data were extracted from peer-reviewed journals using MEDLINE and EMBASE databases, and the following terms (platelets, platelet receptors, CD markers, integrins, tetraspanins, transmembrane receptors, prostaglandin receptors, immunoglobulin superfamily receptors) were used.
authors.affiliation: Muhammad Saboor, Baqai Institute of Hematology, Baqai Medical University, Karachi, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Saboor
authors.affiliation: Qamar Ayub, Baqai Institute of Medical Technology, Baqai Medical University, Karachi, Pakistan.
authors.forename: Qamar
authors.initials: Q
authors.lastname: Ayub
authors.affiliation: SaminaIlyas, Baqai Institute of Hematology, Baqai Medical University, Karachi, Pakistan.
authors.forename: Samina
authors.initials: S
authors.lastname: Ilyas
authors.affiliation: Moinuddin, Baqai Institute of Hematology, Baqai Medical University, Karachi, Pakistan.
authors.lastname: Moinuddin
keywords: Integrins; Platelet receptors; Selectins; Tetraspanins