title: Cardiac troponin I in non- acute coronary syndrome patients with chronic kidney disease.
abstract: OBJECTIVE
  The aim of this study was to assess the results of troponin I (cTnI) in non- acute Coronary Syndrome (ACS) patients with chronic kidney disease (CKD). We also examined the risk factors for elevated cTnI in non-ACS patients with CKD and whether stage 5 CKD modifies the associations of elevated cTnI and the risk factors in non-ACS patients with CKD.
  
  
  METHODS
  A retrospective study was performed. Logistic regression models were used.
  
  
  RESULTS
  293 non-ACS patients with CKD were included in the current study. 43.34% non-ACS patients with CKD have an elevated cTnI level and 5.12% have an elevated cTnT level in MI range. In CKD patients without ACS and heart failure, only 26.03% (38/146) patients have an elevated cTnT level. In adjusted analyses, age, diastolic blood pressure and congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD. Congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD (OR 2.30, 95% CI 1.08,4.88, P=0.03). Stage 5 CKD does not modify the association of congestive heart failure and an elevated cTnI level.
  
  
  CONCLUSIONS
  43.34% non-ACS patients with CKD and 26.03% CKD patients without ACS and congestive heart failure have an elevated cTnI level. Congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD. Stage 5 CKD does not modify the association of congestive heart failure and an elevated cTnI level.
authors.affiliation: Department of Nephrology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
authors.forename: Shanying
authors.initials: S
authors.lastname: Chen
authors.affiliation: Department of Nephrology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
authors.forename: Chunhong
authors.initials: C
authors.lastname: Huang
authors.affiliation: Department of Nephrology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
authors.forename: Bide
authors.initials: B
authors.lastname: Wu
authors.affiliation: Department of Nephrology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
authors.forename: Xuejian
authors.initials: X
authors.lastname: Lian
authors.affiliation: Clinical Laboratory, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
authors.forename: Xuqiao
authors.initials: X
authors.lastname: Mei
authors.affiliation: Department of Nephrology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
authors.forename: Jianxin
authors.initials: J
authors.lastname: Wan
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D052279:Creatine Kinase, MB Form / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D051436:Renal Insufficiency, Chronic / Q000097:blood* / Q000150:complications* / Q000175:diagnosis; D012189:Retrospective Studies; D012307:Risk Factors; D019210:Troponin I / Q000097:blood*; D055815:Young Adult
chemical_list: D019210:Troponin I; D052279:Creatine Kinase, MB Form