title: Mastectomy for management of breast cancer in Ibadan, Nigeria.
abstract: BACKGROUND
  Modified radical mastectomy remains the standard therapeutic surgical operation for breast cancer in most parts of the world. This retrospective study reviews mastectomy for management of breast cancer in a surgical oncology division over a ten year period.
  
  
  METHODS
  We reviewed the case records of consecutive breast cancer patients who underwent mastectomy at the Surgical Oncology Division, University College Hospital (UCH) Ibadan between November 1999 and October 2009.
  
  
  RESULTS
  Of the 1226 newly diagnosed breast cancer patients over the study period, 431 (35.2%) patients underwent mastectomy making an average of 43 mastectomies per year. Most patients were young women, premenopausal, had invasive ductal carcinoma and underwent modified radical mastectomy as the definitive surgical treatment. Prior to mastectomy, locally advanced tumors were down staged in about half of the patients that received neo-adjuvant combination chemotherapy. Surgical complication rate was low. The most frequent operative complication was seroma collection in six percent of patients. The average hospital stay was ten days and most patients were followed up at the surgical outpatients department for about two years post-surgery.
  
  
  CONCLUSIONS
  There was low rate of mastectomy in this cohort which could partly be attributable to late presentation of many patients with inoperable local or metastatic tumors necessitating only palliative or terminal care. Tumor down-staging with neo-adjuvant chemotherapy enhanced surgical loco-regional tumor control in some patients. The overall morbidity and the rates of postoperative events were minimal. Long-term post-operative out-patients follow-up was not achieved as many patients were lost to follow up after two years of mastectomy.
authors.affiliation: Division of Oncology, Department of Surgery, College of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria. toogundiran@yahoo.co.uk.
authors.forename: Temidayo O
authors.initials: TO
authors.lastname: Ogundiran
authors.forename: Omobolaji O
authors.initials: OO
authors.lastname: Ayandipo
authors.forename: Adeyinka F
authors.initials: AF
authors.lastname: Ademola
authors.forename: Clement A
authors.initials: CA
authors.lastname: Adebamowo
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000601:surgery*; D018567:Breast Neoplasms, Male / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000601:surgery*; D003906:Developing Countries; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D015411:Mastectomy, Modified Radical / Q000706:statistics & numerical data; D008875:Middle Aged; D009549:Nigeria; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D016896:Treatment Outcome