title: Is this mine? small RNAs help to decide.
abstract: Genomes are constantly challenged by invaders, so determining what belongs is crucial. Small RNAs silence alien DNA, but Conine et al. (2013), Seth et al. (2013), and Wedeles et al. (2013) now report in Cell and Developmental Cell that these tiny transcripts can also license trusted DNA for expression.
authors.affiliation: Institute for Molecular Biology, Ackermannweg 4, D-55128 Mainz, Germany; Graduate Program in Areas of Basic and Applied Biology, University of Porto, 4099-003 Porto, Portugal.
authors.forename: Bruno F M
authors.initials: BF
authors.lastname: de Albuquerque
authors.affiliation: Institute for Molecular Biology, Ackermannweg 4, D-55128 Mainz, Germany. Electronic address: r.ketting@imb.de.
authors.forename: René F
authors.initials: RF
authors.lastname: Ketting
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics*; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D044127:Epigenesis, Genetic; D020868:Gene Silencing; D005854:Germ Cells / Q000378:metabolism*; D018510:RNA, Helminth / Q000235:genetics*; D034741:RNA, Small Interfering / Q000235:genetics* / Q000378:metabolism*
chemical_list: C544459:CSR-1 protein, C elegans; D029742:Caenorhabditis elegans Proteins; D018510:RNA, Helminth; D034741:RNA, Small Interfering