title: Defining kidney biology to understand renal disease.
abstract: The Kidney Research National Dialogue represents a novel effort by the National Institute of Diabetes and Digestive and Kidney Diseases to solicit and prioritize research objectives from the renal research and clinical communities. The present commentary highlights selected scientific opportunities specific to the study of renal development, physiology, and cell biology. Describing such fundamental kidney biology serves as a necessary foundation for translational and clinical studies that will advance disease care and prevention. It is intended that these objectives foster and focus scientific efforts in these areas in the coming decade and beyond.
authors.affiliation: Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia;, †Center for Systems Biology and Program in Membrane Biology, and Division of Nephrology, Massachussetts General Hospital, Harvard University, Boston, Massachusetts;, ‡Renal Division, Brigham and Women's Hospital, Harvard University, Boston, Massachusetts;, §Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, California;, ‖Renal Division, Washington University School of Medicine, Washington University in St. Louis, St. Louis, Missouri;, ¶Departments of Medicine and Physiology, Emory University School of Medicine, Atlanta, Georgia;, *Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, ††National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
authors.forename: Melissa H
authors.initials: MH
authors.lastname: Little
authors.forename: Dennis
authors.initials: D
authors.lastname: Brown
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Humphreys
authors.forename: Andrew P
authors.initials: AP
authors.lastname: McMahon
authors.forename: Jeffrey H
authors.initials: JH
authors.lastname: Miner
authors.forename: Jeff M
authors.initials: JM
authors.lastname: Sands
authors.forename: Ora A
authors.initials: OA
authors.lastname: Weisz
authors.forename: Chris
authors.initials: C
authors.lastname: Mullins
authors.forename: Deborah
authors.initials: D
authors.lastname: Hoshizaki
mesh_terms: D000367:Age Factors; D000375:Aging; D000818:Animals; D035843:Biomedical Research; D006801:Humans; D007668:Kidney / Q000196:embryology / Q000473:pathology / Q000503:physiopathology; D007674:Kidney Diseases / Q000196:embryology / Q000453:epidemiology / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D009398:Nephrology; D012307:Risk Factors; D049490:Systems Biology