title: Solitary congenital hypertrophy of the retinal pigment epithelium features by high-definition optical coherence tomography.
abstract: OBJECTIVE
  To describe the features of solitary congenital hypertrophy of the retinal pigment epithelium (CHRPE) using high-definition optical coherence tomography (HD-OCT).
  
  
  METHODS
  This was a retrospective, observational, noncomparative case series including 16 consecutive patients with solitary CHRPE. We describe the clinical and OCT features of CHRPE using the 5 radial lines acquisition OCT protocol over the CHRPE and the retina next to the tumor.
  
  
  RESULTS
  The mean patient age was 54 years (median 57 years; range 8-76 years). The CHRPE lesion was outside the posterior pole in 14 of the patients (8 temporal, 3 superior, 2 nasal, and 1 inferior quadrant) and 2 peripapillary. Fifteen patients (94%) showed retinal thinning and complete photoreceptor loss overlying the CHRPE. The RPE hyperreflectivity was found in all patients. The retina over the lesion measured a mean of 60.3% (range 41%-95%) of the thickness of the adjacent normal retina.
  
  
  CONCLUSIONS
  High-definition OCT showed retinal thinning, photoreceptor loss, and RPE hyperreflectivity in solitary CHRPE lesions.
authors.affiliation: Ophthalmology Unit, Fundación Alcorcón University Hospital, Madrid - Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Orduña-Azcona
authors.forename: Pablo
authors.initials: P
authors.lastname: Gili
authors.forename: Sofia
authors.initials: S
authors.lastname: De Manuel-Triantafilo
authors.forename: Patricia
authors.initials: P
authors.lastname: Flores-Rodriguez
mesh_terms: D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000151:congenital; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000151:congenital / Q000175:diagnosis*; D055213:Retinal Pigment Epithelium / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*