title: Growth hormone insensitivity syndrome: unusual oral manifestations.
abstract: Children with significant growth retardation and normal levels of growth hormone are diagnosed with growth hormone insensitivity. The main oral findings observed in patients with growth hormone insensitivity syndrome (GHIS) are underdeveloped jaws, crowded teeth and delayed eruption of permanent teeth. This manuscript describes a 9-year-old child diagnosed with GHIS, who had delayed eruption of permanent teeth and 14 unerupted supernumerary teeth. All supernumerary teeth were extracted except for two maxillary and one mandibular teeth which were difficult to identify and access. Multiple supernumerary teeth have never been reported before in patients with GHIS.
authors.affiliation: Department of Restorative Dentistry, School of Dentistry, University of Cuiaba, Cuiaba, Brazil. ahborges@brturbo.com.br.
authors.forename: Alvaro Henrique
authors.initials: AH
authors.lastname: Borges
authors.affiliation: Integrated Dentistry Sciences Program, School of Dentistry, University of Cuiaba, Cuiaba, Brazil.
authors.forename: Carlos Rodrigo Barros
authors.initials: CR
authors.lastname: Siqueira
authors.affiliation: Department of Restorative Dentistry, School of Dentistry, University of Cuiaba, Cuiaba, Brazil.
authors.forename: Fábio Luis Miranda
authors.initials: FL
authors.lastname: Pedro
authors.affiliation: Department of Restorative Dentistry, School of Dentistry, University of Cuiaba, Cuiaba, Brazil.
authors.forename: Vinícius Canavarros
authors.initials: VC
authors.lastname: Palma
authors.affiliation: Department of Clinics and Surgery, Federal University of Alfenas, Alfenas, Minas Gerais, Brazil.
authors.forename: Vivien Thiemy
authors.initials: VT
authors.lastname: Sakai
authors.affiliation: Department of Restorative Dentistry, School of Dentistry, University of Cuiaba, Cuiaba, Brazil.
authors.forename: Luiz Evaristo Ricci
authors.initials: LE
authors.lastname: Volpato
mesh_terms: D002648:Child; D054893:Cone-Beam Computed Tomography; D005260:Female; D006801:Humans; D046150:Laron Syndrome / Q000150:complications*; D010027:Osteotomy; D011862:Radiography, Panoramic; D014081:Tooth Extraction; D014096:Tooth, Supernumerary / Q000000981:diagnostic imaging / Q000601:surgery*