title: Novel TP53 gene mutation and correlation with p53 immunohistochemistry in a mixed epithelial carcinoma of the endometrium.
abstract: ► We examine the correlation between p53 immunohistochemistry and TP53 gene mutation status in a mixed epithelial endometrial carcinoma. ► We describe a novel R306* (c.916C > T) mutation in exon 8 of the TP53 gene. ► We propose that the distinction between Type I and Type II endometrial carcinomas may be more fluid than previously believed.
authors.affiliation: University of Colorado, Department of Pathology, USA ; MD Anderson Cancer Center, Department of Pathology, USA.
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Sholl
authors.affiliation: University of Colorado, Department of Pathology, USA.
authors.forename: Dara L
authors.initials: DL
authors.lastname: Aisner
authors.affiliation: University of Colorado, Department of Obstetrics and Gynecology, USA.
authors.forename: Kian
authors.initials: K
authors.lastname: Behbakht
authors.affiliation: University of Colorado, Department of Pathology, USA.
authors.forename: Miriam D
authors.initials: MD
authors.lastname: Post
keywords: Endometrioid carcinoma; Mixed epithelial carcinoma; Serous carcinoma; TP53 gene; p53 immunohistochemistry