title: Calciphylaxis: a rare but potentially fatal event of chronic kidney disease. Case report.
abstract: Calciphylaxis or calcific uremic arteriolopathy is a rare cutaneous-systemic disease occurring in patients with advanced chronic kidney disease. The classical clinical picture is that of a necrotic and progressive skin ulcer of reticular pattern, mostly in the lower legs and susceptible to local infection. It is a product of mural calcification and occlusion of cutaneous and sub-cutaneous arteries and arterioles. The authors report the case of a 73-year-old male patient in his late stage of renal disease presenting severe necrotic cutaneous ulcers on lower legs followed by local and systemic infection and death due to sepse after parathyroidectomy.
authors.affiliation: São Paulo State University "Júlio de Mesquita Filho", Botucatu Medical School, Department of Dermatology and Radiotherapy, BotucatuSP, Brazil.
authors.forename: Silvio Alencar
authors.initials: SA
authors.lastname: Marques
authors.affiliation: Brazilian Society of Dermatology, São PauloSP, Brazil.
authors.forename: Aline Cruz
authors.initials: AC
authors.lastname: Kakuda
authors.affiliation: Brazilian Society of Dermatology, São PauloSP, Brazil.
authors.forename: Thais Jung
authors.initials: TJ
authors.lastname: Mendaçolli
authors.affiliation: São Paulo State University "Júlio de Mesquita Filho", Botucatu Medical School, Department of Dermatology and Radiotherapy, BotucatuSP, Brazil.
authors.forename: Luciana P Fernandes
authors.initials: LP
authors.lastname: Abbade
authors.affiliation: São Paulo State University "Júlio de Mesquita Filho", Botucatu Medical School, Department of Pathology, BotucatuSP, Brazil.
authors.forename: Mariângela Esther Alencar
authors.initials: ME
authors.lastname: Marques
mesh_terms: D000368:Aged; D002115:Calciphylaxis / Q000209:etiology* / Q000473:pathology; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology* / Q000473:pathology; D008297:Male; D009336:Necrosis; D051436:Renal Insufficiency, Chronic / Q000150:complications* / Q000473:pathology; D012867:Skin / Q000473:pathology