title: Inflammatory vitiligo versus hypopigmented mycosis fungoides in a 58-year-old Indian female.
abstract: Vitiligo, particularly the rarer inflammatory variant, may be difficult to distinguish from hypopigmented mycosis fungoides (MF) clinically. Complicating the distinction is that when biopsies are taken from the periphery of early vitiliginous lesions or from lesions with an inflammatory border (inflammatory vitiligo), a dermal lymphocytic infiltrate, exocytosis, interface dermatitis, and mild spongiosis may be seen, all resembling the findings seen in hypopigmented MF. We present a case demonstrating the difficulty in differentiating between these two diseases and examine some characteristic clinical and histopathological features of each. Often, a conclusive diagnosis cannot be made, necessitating close follow-up of the patient and monitoring for progression of their disease over time.
authors.affiliation: Department of Dermatology, Dermatology Residency Program at Lehigh Valley Health Network, Advanced Dermatology Associates Ltd., Allentown, PA, USA ; Department of Dermatology, Philadelphia College of Osteopathic Medicine, Allentown, PA, USA.
authors.forename: Luis A
authors.initials: LA
authors.lastname: Soro
authors.affiliation: Department of Dermatology, Lehigh Valley Health Network, Advanced Dermatology Associates Ltd., Allentown, PA, USA.
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Gust
authors.affiliation: Department of Dermatology, Lehigh Valley Health Network, Advanced Dermatology Associates Ltd., Allentown, PA, USA.
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Purcell
keywords: Cutaneous T-cell lymphoma; hypopigmented mycosis fungoides; inflammatory vitiligo