title: [Opioid therapy for chronic noncancer pain: retrospective analysis of patients hospitalized for withdrawal].
abstract: OBJECTIVE
  The prescription of opioids for the treatment of chronic non-cancer pain (CNCP) is not recommended for all of them, and can expose the patients to a benefit/risk ratio unfavorable. The objective of this study was to evaluate the management of patients hospitalized at the centre for evaluation and treatment of pain for opioid withdrawal, their outcome during hospitalization.
  
  
  METHODS
  This is a retrospective descriptive study. The medical record of each patient was consulted to identify relevant data (demographics, treatments at the entrance and discharge of hospitalization, comorbidities, rating scale of pain).
  
  
  RESULTS
  During the study period (3 years), 53 patients (64% of women), with a median age of 52 years, were included. Pain was mainly back pain and neck pain (52%). Morphine (43%) and fentanyl (42%) were the most frequently used opioids. At admission, 62% of patients had a depressive state. At hospital discharge, withdrawal was total in 18 patients (34%) and a total improvement of pain was observed for 19% of them.
  
  
  CONCLUSIONS
  In this study, 57% of patients received, at admission to hospital, an opioid other than morphine in the treatment of CNCP. The management of pain offered by the pain clinic led to a total or partial opioid withdrawal in 94% of patients.
authors.affiliation: Département de Pharmacologie médicale et Toxicologie, Centre d'Addictovigilance, Hôpital Lapeyronie, CHRU Montpellier, UM1, Montpellier, France.
authors.forename: Delinger
authors.initials: D
authors.lastname: Faure
authors.affiliation: Centre d'Évaluation et de Traitement de la Douleur (CETD), Hôpital Saint-Éloi, CHRU Montpellier, UM1, Montpellier, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Giniès
authors.affiliation: Département de Pharmacologie médicale et Toxicologie, Centre d'Addictovigilance, Hôpital Lapeyronie, CHRU Montpellier, UM1, Montpellier, France.
authors.forename: Céline
authors.initials: C
authors.lastname: Eiden
authors.affiliation: Département de Pharmacologie médicale et Toxicologie, Centre d'Addictovigilance, Hôpital Lapeyronie, CHRU Montpellier, UM1, Montpellier, France.
authors.forename: Laure
authors.initials: L
authors.lastname: Portet
authors.affiliation: Département de Pharmacologie médicale et Toxicologie, Centre d'Addictovigilance, Hôpital Lapeyronie, CHRU Montpellier, UM1, Montpellier, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Peyrière
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001416:Back Pain / Q000188:drug therapy; D059350:Chronic Pain / Q000188:drug therapy*; D003863:Depression / Q000453:epidemiology; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D019547:Neck Pain / Q000188:drug therapy; D012189:Retrospective Studies; D013375:Substance Withdrawal Syndrome / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine; D005283:Fentanyl