title: [Association of NMDAR, NR2A, and NR2B with cognitive impairment in diabetic patients].
abstract: Cognitive impairment in diabetes (CID) is a severe chronic complication of diabetes mellitus, and its pathogenesis has not yet been fully understood. Increasing evidence has shown that the distribution and expression of N-methyl-D-aspartame receptor (NMDAR) and subunits NR2A and NR2B, which all participated in the development of the central nervous system and formation of learning and memory, are correlated with the occurrence and development of CID.
authors.affiliation: Department of Pathology and Pathophysiology, Faculty of Basic Medical Science, Kunming Medical University, Kunming 650500, China. E-mail: 261334618@qq.com.
authors.forename: Xiaopeng
authors.initials: X
authors.lastname: Wang
authors.forename: Yongjie
authors.initials: Y
authors.lastname: Huang
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.forename: Yingying
authors.initials: Y
authors.lastname: Zou
mesh_terms: D002490:Central Nervous System; D003072:Cognition Disorders / Q000150:complications / Q000235:genetics*; D003920:Diabetes Mellitus / Q000503:physiopathology*; D006801:Humans; D008568:Memory; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism*
chemical_list: C120997:NR2A NMDA receptor; C121001:NR2B NMDA receptor; D016194:Receptors, N-Methyl-D-Aspartate