title: The usefulness of an autologous blood clot combined with gelatin for regeneration of periodontal tissue.
abstract: Several growth factors have been used in tissue regeneration therapy. Here we describe the use of an autologous blood clot combined with gelatin for teeth affected by severe periodontitis and vertical root fracture treated using three oral surgical procedures: periodontal flap surgery, intentional tooth replantation (IR), and tooth autotransplantation. Treatment with a blood clot improved the condition of the periodontal tissue, including reduction of pocket depth. Radiographical images demonstrated no evidence of ankylosis, and revealed the presence of alveolar bone regeneration. Our successful clinical outcome suggests that use of an autologous blood clot combined with gelatin is clinically effective for regeneration of lost periodontal tissue.
authors.affiliation: Section of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kabashima
authors.forename: Takako
authors.initials: T
authors.lastname: Sakai
authors.forename: Kunitaka
authors.initials: K
authors.lastname: Mizobe
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Nakamuta
authors.forename: Kenichi
authors.initials: K
authors.lastname: Kurita
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Terada
mesh_terms: D000328:Adult; D001777:Blood Coagulation; D005260:Female; D005780:Gelatin / Q000008:administration & dosage*; D006801:Humans; D008875:Middle Aged; D010519:Periodontium / Q000503:physiopathology*; D012038:Regeneration
chemical_list: D005780:Gelatin