title: [Hematological changes in adolescent anorexia nervosa].
abstract: OBJECTIVE
  Hematological changes often occur in patients with acute anorexia nervosa (AN). However, the relationship between these disturbances and other clinical parameters remains unclear.
  
  
  METHODS
  Leucocyte, erythrocyte, and thrombocyte counts as well as hematocrit, hemoglobin, and differential blood counts were collected at admission and after weight restoration in 88 female adolescent patients with the diagnosis of AN according to DSM-IV. These were then compared to clinical parameters.
  
  
  RESULTS
  At admission, there were mild changes in the blood count, most of which, however, were reversible after weight gain. Patients with a greater weight loss, a lower age-adjusted BMI, and a history of taking psychotropic drugs were more likely to develop hematological abnormalities.
  
  
  CONCLUSIONS
  Although most of the hematological changes in adolescent patients with AN were mild, patients with high weight loss and/or low age-adjusted BMI as well as those on psychotropic medication should be monitored carefully in order to avoid severe medical complications. An altered immune function in adult patients with chronic AN might contribute to a higher rate of infections and thus to an increased mortality.
authors.affiliation: Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters der Universitätsklinik der RWTH Aachen, <location>Deutschland</location>
authors.forename: Katharina
authors.initials: K
authors.lastname: Bühren
authors.affiliation: Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters der Universitätsklinik der RWTH Aachen, <location>Deutschland</location>
authors.forename: Laura
authors.initials: L
authors.lastname: Gärtner
authors.affiliation: Institut für Medizinische Statistik, RWTH Aachen University, <location>Deutschland</location>
authors.forename: Lieven N
authors.initials: LN
authors.lastname: Kennes
authors.affiliation: Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters der Universitätsklinik der RWTH Aachen, <location>Deutschland</location>
authors.forename: Jochen
authors.initials: J
authors.lastname: Seitz
authors.affiliation: Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters der Universitätsklinik der RWTH Aachen, <location>Deutschland</location>
authors.forename: Ulrich
authors.initials: U
authors.lastname: Hagenah
authors.affiliation: Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters der Universitätsklinik der RWTH Aachen, <location>Deutschland</location>
authors.forename: Beate
authors.initials: B
authors.lastname: Herpertz-Dahlmann
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000856:Anorexia Nervosa / Q000097:blood* / Q000534:rehabilitation; D015992:Body Mass Index; D002648:Child; D004906:Erythrocyte Count; D005260:Female; D005500:Follow-Up Studies; D006400:Hematocrit; D006452:Hemoglobinometry; D006801:Humans; D007958:Leukocyte Count; D010976:Platelet Count; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use; D012189:Retrospective Studies; D015430:Weight Gain / Q000502:physiology; D055815:Young Adult
chemical_list: D011619:Psychotropic Drugs
keywords: Anorexia nervosa; Behandlung; Blutbild; Essstörung; Gewichtsrehabilitation; Laborveränderungen; anorexia nervosa; blood count; eating disorder; hematologic changes; hämatologische Veränderungen; treatment; weight restoration