title: Serum levels of brain-derived neurotrophic factor (BNDF) in multiple sclerosis patients with Trichuris suis ova therapy.
abstract: We previously analysed clinical and immunological parameters under Trichuris suis ova (TSO) therapy in four patients with secondary progressive multiple sclerosis. The serum Brain-derived neurotrophic factor (BDNF) levels of these four patients were assessed before, during and after therapy with TSO and showed significant decrease of BDNF during TSO therapy (p < 0.05).
authors.affiliation: Department of Neurology and Experimental Neurology, Charité Campus Mitte - Universitätsmedizin Berlin, Germany.
authors.forename: Berit
authors.initials: B
authors.lastname: Rosche
authors.affiliation: Department of Psychiatry, Charité Campus Mitte - Universitätsmedizin Berlin, Germany.
authors.forename: Jonas
authors.initials: J
authors.lastname: Werner
authors.affiliation: Department of Neurology and Experimental Neurology, Charité Campus Mitte - Universitätsmedizin Berlin, Germany.
authors.forename: Friderike Joëlle
authors.initials: FJ
authors.lastname: Benzel
authors.affiliation: Department of Neurology and Experimental Neurology, Charité Campus Mitte - Universitätsmedizin Berlin, Germany.
authors.forename: Lutz
authors.initials: L
authors.lastname: Harms
authors.affiliation: Competence Centre for Sleep Medicine, Charité Campus Benjamin Franklin - Universitätsmedizin Berlin, Germany.
authors.forename: Heidi
authors.initials: H
authors.lastname: Danker-Hopfe
authors.affiliation: Department of Psychiatry, Charité Campus Mitte - Universitätsmedizin Berlin, Germany.
authors.forename: Rainer
authors.initials: R
authors.lastname: Hellweg
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology / Q000378:metabolism; D019208:Brain-Derived Neurotrophic Factor / Q000097:blood* / Q000276:immunology; D006801:Humans; D056747:Immunomodulation; D020528:Multiple Sclerosis, Chronic Progressive / Q000097:blood / Q000628:therapy*; D010063:Ovum / Q000276:immunology; D010865:Pilot Projects; D014258:Trichuris / Q000276:immunology*
chemical_list: D019208:Brain-Derived Neurotrophic Factor