title: In situ derivatization coupled to microextraction by packed  sorbentand gas chromatography for the automated determination  ofhaloacetic acids in chlorinated water.
abstract: A novel analytical method is reported for the determination of monochloroacetic acid, dichloroacetic acid, trichloroacetic acid, monobromoacetic acid, and dibromoacetic acid. These are the five haloacetic acids (HAAs) for which the U.S. Environmental Protection Agency (US EPA) has regulated a maximum contamination level (MCL) of 0.060 mg L−1for the sum of their concentrations in drinking waters. Themethod uses in situ aqueous derivatization, followed by microextraction by packed sorbent (MEPS) priorto gas chromatography–mass spectrometry (GC–MS). The parameters affecting derivatization and extraction were optimized with a view to obtaining maximum sensitivity. The HAAs were derivatized with 2,2,2-trifluroethylamine (TFEA), using N-ethyl-N'-(3-dimethylaminopropyl) carbodiimide (EDC) as a condensation agent. The reaction occurred in aqueous medium and was carried out in 10 min in the vial of anautosampler used to perform microextraction by packed sorbent. The whole process, from the mixing of the reagents for the derivatization, was automated. Precision values varied from 4.2 to 9.8% (as intra-day relative standard deviation, RSD) and 9.4 to 14% (as inter-day RSD). The recoveries from spiked concentrations ranged from 83 to 117%, revealing the accuracy of the method. The detection limits ranged from 0.36 to 1.2 g L−1, such that it is possible to measure the US EPA MCL in drinking waters. The method developed was applied to the analysis of HAAs in drinking and swimming pool water from Salamanca(North West of Spain).
authors.forename: Ana María
authors.initials: AM
authors.lastname: Casas Ferreira
authors.forename: María Esther
authors.initials: ME
authors.lastname: Fernández Laespada
authors.forename: José Luis
authors.initials: JL
authors.lastname: Pérez Pavón
authors.forename: Bernardo Moreno
authors.initials: BM
authors.lastname: Cordero
mesh_terms: D000085:Acetates / Q000737:chemistry* / Q000302:isolation & purification; D060766:Drinking Water / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D057230:Limit of Detection; D052617:Solid Phase Microextraction / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D000085:Acetates; D060766:Drinking Water; D014874:Water Pollutants, Chemical