title: Livedoid vasculopathy associated with peripheral neuropathy: a report of two cases.
abstract: Livedoid vasculopathy (LV) is a chronic and recurrent disease consisting of livedo reticularis and symmetric ulcerations, primarily located on the lower extremities, which heal slowly and leave an atrophic white scar ("atrophie blanche"). Neurological involvment is rare and presumed to be secondary to the ischemia from vascular thrombosis of the vasa nervorum. Laboratory evaluation is needed to exclude secondary causes such as hyper-coagulable states, autoimmune disorders and neoplasms. We present two patients with a rare association of peripheral neuropathy and LV, thereby highlighting the importance of a multidisciplinary approach to reach the correct diagnosis.
authors.affiliation: Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Dermatology Service, Porto AlegreRS, Brazil.
authors.forename: Mariana Quirino
authors.initials: MQ
authors.lastname: Tubone
authors.affiliation: Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Dermatology Service, Porto AlegreRS, Brazil.
authors.forename: Gabriela Fortes
authors.initials: GF
authors.lastname: Escobar
authors.affiliation: Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Dermatology Service, Porto AlegreRS, Brazil.
authors.forename: Juliano
authors.initials: J
authors.lastname: Peruzzo
authors.affiliation: Federal University of Rio Grande do Sul, Porto AlegreRS, Brazil.
authors.forename: Pedro
authors.initials: P
authors.lastname: Schestatsky
authors.affiliation: Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Dermatology Service, Porto AlegreRS, Brazil.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Maldonado
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D054068:Livedo Reticularis / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000150:complications* / Q000473:pathology; D012883:Skin Ulcer / Q000473:pathology