title: Light scattering and light transmittance of cadaver eye-explanted intraocular lenses of different materials.
abstract: OBJECTIVE
  To evaluate light scattering and light transmittance in cadaver eye-explanted intraocular lenses (IOLs) manufactured from different materials.
  
  
  METHODS
  John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
  
  
  METHODS
  Experimental study.
  
  
  METHODS
  Forty-nine pseudophakic cadaver eyes were selected according to IOL material/type and implantation duration, and the IOLs were explanted. Hydrophobic acrylic, hydrophilic acrylic, poly(methyl methacrylate) (PMMA), and silicone IOLs were included. Gross and light microscopy was performed for all IOLs. Light scattering was measured with an EAS 1000 Scheimpflug camera, and light transmittance was assessed using a Lambda 35 UV/Vis spectrophotometer (single-beam configuration with an RSA PE-20 integrating sphere). Analyses were performed at room temperature in the hydrated state and compared with analyses of controls.
  
  
  RESULTS
  The highest levels of surface light scattering were measured for 3-piece hydrophobic acrylic, which was also the IOL type with the longest implantation duration among the Acrysof hydrophobic acrylic IOLs. Hydrophilic acrylic, PMMA, and silicone IOLs exhibited relatively low light-scattering levels. The lowest light-scattering levels were observed with PMMA IOLs (1-piece looped and 3-piece) and plate silicone IOLs, which represent the IOL types with the longest implantation duration in this series. Light transmittance values measured for all IOL types appeared to be similar to the values of the corresponding control IOLs.
  
  
  CONCLUSIONS
  The phenomenon of surface light scattering (nanoglistenings) is more particularly related to hydrophobic acrylic IOLs and increases with implantation time. No significant effect of surface light scattering on IOL light transmittance was found.
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Morris, Werner, Liu, Stallings, Floyd), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; and Visão Institutos Oftalmológicos Associados (Barra), Brasília, DF, Brazil.
authors.forename: Caleb
authors.initials: C
authors.lastname: Morris
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Morris, Werner, Liu, Stallings, Floyd), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; and Visão Institutos Oftalmológicos Associados (Barra), Brasília, DF, Brazil. Electronic address: liliana.werner@hsc.utah.edu.
authors.forename: Liliana
authors.initials: L
authors.lastname: Werner
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Morris, Werner, Liu, Stallings, Floyd), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; and Visão Institutos Oftalmológicos Associados (Barra), Brasília, DF, Brazil.
authors.forename: Daniel
authors.initials: D
authors.lastname: Barra
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Morris, Werner, Liu, Stallings, Floyd), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; and Visão Institutos Oftalmológicos Associados (Barra), Brasília, DF, Brazil.
authors.forename: Erica
authors.initials: E
authors.lastname: Liu
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Morris, Werner, Liu, Stallings, Floyd), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; and Visão Institutos Oftalmológicos Associados (Barra), Brasília, DF, Brazil.
authors.forename: Shannon
authors.initials: S
authors.lastname: Stallings
authors.affiliation: From the Department of Ophthalmology and Visual Sciences (Morris, Werner, Liu, Stallings, Floyd), John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; and Visão Institutos Oftalmológicos Associados (Barra), Brasília, DF, Brazil.
authors.forename: Anne
authors.initials: A
authors.lastname: Floyd
mesh_terms: D000180:Acrylic Resins; D002102:Cadaver; D020878:Device Removal; D006801:Humans; D007910:Lenses, Intraocular; D008027:Light; D055095:Optics and Photonics; D019904:Polymethyl Methacrylate; D012542:Scattering, Radiation; D012826:Silicone Elastomers; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000180:Acrylic Resins; D012826:Silicone Elastomers; D019904:Polymethyl Methacrylate