title: Health-related quality of life in hemodialysis patients: an Iranian multi-center study.
abstract: BACKGROUND
  The effectiveness of health care and health policy developments are often determined by health-related quality of life (HRQOL) assessment.
  
  
  OBJECTIVE
  The objective of this study was to explore the potential corresponding factors and traditional biomarkers of HRQOL in a large number of Iranian hemodialysis patients.
  
  
  METHODS
  A total of 6,930 chronic hemodialysis (HD) patients enrolled. KDCS-SF version 1.3 questionnaire was used to assess the health related quality of life (HRQOL). We pooled PCS, MCS and KDCS scores with random effect model from 19 similar studies performed between 1996 and 2010.
  
  
  RESULTS
  The mean age was 54.4 ± 17.1 years. Mean PCS, MCS and KDCS scores obtained for the study cohort were 40.79 ± 20.10, 47.79 ± 18.31 and 57.97 ± 11.70, respectively; the total score of SF-36 plus KDCS was 51.12 ± 13.41 as well. The most common primary known disease was hypertension (31.9%) and the second etiology was diabetes (25.5%). In multilevel logistic regression, Kt/V between 1 and 1.2 and PCS, KDCS more than 50 were considered as a significant reduction in the risk of hospitalization.
  
  
  CONCLUSIONS
  This study showed that PCS and MCS score were slightly more than overall results while KDCS was slightly less than overall results. In addition, dialysis adequacy with Kt/V between 1 and 1.2 is associated with lower rate of hospitalization.
authors.affiliation: Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IR Iran.
authors.forename: Zohreh
authors.initials: Z
authors.lastname: Rostami
authors.affiliation: Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IR Iran.
authors.forename: Behzad
authors.initials: B
authors.lastname: Einollahi
authors.affiliation: Department of Nephrology, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Mahboob
authors.initials: M
authors.lastname: Lessan-Pezeshki
authors.affiliation: Department of Nephrology, Artesh University of Medical Sciences, Tehran, IR Iran.
authors.forename: Azam
authors.initials: A
authors.lastname: Soleimani Najaf Abadi
authors.affiliation: Department of Nephrology, Ardabil University of Medical Sciences, Ardabil, IR Iran.
authors.forename: Susan
authors.initials: S
authors.lastname: Mohammadi Kebar
authors.affiliation: Department of Nephrology, Ahvaz University of Medical Sciences, Ahvaz, IR Iran.
authors.forename: Heshmatollah
authors.initials: H
authors.lastname: Shahbazian
authors.affiliation: Department of Nephrology, Sari University of Medical Sciences, Sari, IR Iran.
authors.forename: Atieh
authors.initials: A
authors.lastname: Makhlough
authors.affiliation: Department of Nephrology, Urmia University of Medical Sciences, Urmia, IR Iran.
authors.forename: Khadijeh
authors.initials: K
authors.lastname: Makhdoomi
authors.affiliation: Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IR Iran.
authors.forename: Mahmood
authors.initials: M
authors.lastname: Salesi
authors.affiliation: Department of Nephrology, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
authors.forename: Mojgan
authors.initials: M
authors.lastname: Jalalzadeh
keywords: Kidney Diseases; Mental Status Schedule; Quality of Life; Renal Dialysis