title: Systemic sarcoidosis induced by etanercept: first Brazilian case report.
abstract: The antagonists of tumor necrosis factor alpha (TNF-α) are increasingly being used in the treatment of inflammatory and autoimmune diseases. Several adverse effects of these drugs have been reported, including the paradoxical development of sarcoidosis, especially with the use of etanercept. We present the first Brazilian case report of systemic sarcoidosis induced by etanercept and a literature review.
authors.affiliation: Rio de Janeiro State University, Pedro Ernesto University Hospital, Dermatology Program, Rio de JaneiroRJ, Brazil.
authors.forename: Natasha
authors.initials: N
authors.lastname: Unterstell
authors.affiliation: Rio de Janeiro State University, Pedro Ernesto University Hospital, immunotherapy clinic, dermatology ward, Rio de JaneiroRJ, Brazil.
authors.forename: Aline Lopes
authors.initials: AL
authors.lastname: Bressan
authors.affiliation: Rio de Janeiro State University, Pedro Ernesto University Hospital, Dermatology Program, Rio de JaneiroRJ, Brazil.
authors.forename: Laura Araújo
authors.initials: LA
authors.lastname: Serpa
authors.affiliation: Rio de Janeiro State University, Pedro Ernesto University Hospital, Dermatology Program, Rio de JaneiroRJ, Brazil.
authors.forename: Pérola Peres da
authors.initials: PP
authors.lastname: Fonseca e Castro
authors.affiliation: Rio de Janeiro State University, Pedro Ernesto University Hospital, immunotherapy clinic, dermatology ward, Rio de JaneiroRJ, Brazil.
authors.forename: Alexandre Carlos
authors.initials: AC
authors.lastname: Gripp
mesh_terms: D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D001938:Brazil; D000068800:Etanercept; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects*; D008875:Middle Aged; D018124:Receptors, Tumor Necrosis Factor; D012507:Sarcoidosis / Q000139:chemically induced* / Q000473:pathology; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D018501:Antirheumatic Agents; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha; D000068800:Etanercept