title: Monocyte-derived dendritic cells: Emerging players in the antitumor immune response.
abstract: The elicitation of efficient antitumor immune responses requires the optimal activation of tumor-associated dendritic cells (DCs). Our comparison of the effect of various immunostimulatory treatments on DCs revealed that the best predictor of the success of immunotherapy is not the activation of existing DC populations, but the appearance of a population of monocyte-derived DC in tumor-draining lymph nodes.
authors.affiliation: Malaghan Institute of Medical Research; Wellington, New Zealand ; Victoria University of Wellington; Wellington, New Zealand.
authors.forename: Sabine
authors.initials: S
authors.lastname: Kuhn
authors.affiliation: Malaghan Institute of Medical Research; Wellington, New Zealand.
authors.forename: Franca
authors.initials: F
authors.lastname: Ronchese
keywords: TLR-ligands; dendritic cells; immunotherapy; inflammation; monocyte-derived dendritic cells