title: Rapid developing basaloid squamous cell carcinoma of the uterine cervix in a young adult Taiwanese.
abstract: Basaloid squamous cell carcinoma (BSCC) of the uterine cervix is a rare malignancy of the female genital tract with a poorer clinical outcome than SCC of the uterine cervix. We report a case of BSCC of the uterine cervix developing rapidly in a young adult Taiwanese. A 35-year-old woman, Para 2, visited the emergency room with severe dizziness, palpitations and sudden excessive vaginal bleeding with hemoglobin of 3.6 g/dl. She had been well and healthy but intermittent vaginal spotting developed for around 6 months previously and was treated as abnormal uterine bleeding by ob-gyn practitioners. She had a repeat cesarean operation 16 months prior to this episode and the last Pap smear showed reactive change 12 months ago at our hospital. On examination, she had an ulcerated, necrotic, and punched-out lesion of 5 cm of the cervix. A cervical biopsy revealed poorly differentiated typical BSCC. Abdominal/pelvic computerized tomography and whole body positron emission tomography confirmed FIGO staging IB2. She responded well to concurrent chemoradiotherapy. Follow-up for the patient is ongoing. This is a rapid developing BSCC of the uterine cervix, although we cannot actually ascertain when it started and how rapidly it progressed.
authors.affiliation: University of Malaya, Faculty of Medicine, Departments of Obstetrics and Gynecology, Jalan Universiti, 50603 Kuala Lumpur, Malaysia.
authors.forename: H J
authors.initials: HJ
authors.lastname: Tsai
authors.forename: B
authors.initials: B
authors.lastname: Liou
authors.forename: M C
authors.initials: MC
authors.lastname: Li
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000628:therapy; D059248:Chemoradiotherapy; D018450:Disease Progression; D005260:Female; D006801:Humans; D013624:Taiwan; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000628:therapy