title: The influence of desensitizing dentifrices on pain induced by in-office bleaching.
abstract: The purpose of this study was to evaluate whether the use of desensitizing dentifrices used 15 days prior to and after in-office tooth bleaching could eliminate or reduce tooth sensitivity. After institutional review board approval and informed consent, 45 subjects were selected and divided into 3 groups according to the dentifrice selected: Colgate Total (CT), Colgate Sensitive Pro-Relief (CS) or Sensodyne ProNamel (SP). The subjects used toothpaste and a toothbrush provided to them for 15 days prior to bleaching. They were then submitted to two in-office bleaching sessions (Whiteness HP Blue Calcium). Their tooth sensitivity was assessed using the Visual Analog Scale (VAS) for a week after each session. Their tooth shade alteration was measured with a Vitapan Classical shade guide to determine if the dentifrices could influence the effectiveness of the bleaching agent. The data were submitted to Wilcoxon, Kruskal-Wallis and Mann-Whitney tests (α = 0.05). The use of desensitizing dentifrices did not affect the bleaching efficacy. In regard to tooth sensitivity, there was a statistically significant difference between the results of the Control Group and Group T2 after the first session (p = 0.048). There was no statistically significant difference in the results for the other groups after the first session. In regard to the second session, there was no statistically significant difference in the results for all the groups. The use of a desensitizing dentifrice containing nitrate potassium reduced tooth sensitivity during the bleaching regimen. Dentifrices containing arginine and calcium carbonate did not reduce tooth sensitivity. Color change was not influenced by the dentifrices used.
authors.affiliation: Department of Dentistry, School of Dentistry, Universidade Federal de Santa Catarina, FlorianópolisSC, Brazil.
authors.forename: Carlos Henrique
authors.initials: CH
authors.lastname: Thiesen
authors.affiliation: Department of Dentistry, School of Dentistry, Universidade Federal de Santa Catarina, FlorianópolisSC, Brazil.
authors.forename: Rubens
authors.initials: R
authors.lastname: Rodrigues Filho
authors.affiliation: Department of Dentistry, School of Dentistry, Universidade Federal de Santa Catarina, FlorianópolisSC, Brazil.
authors.forename: Luiz Henrique Maykot
authors.initials: LH
authors.lastname: Prates
authors.affiliation: Division of Restorative Sciences, Ostrow School of Dentistry, University of Southern California, Los AngelesCA, USA.
authors.forename: Neimar
authors.initials: N
authors.lastname: Sartori
mesh_terms: D000293:Adolescent; D000328:Adult; D003116:Color; D045424:Complex Mixtures / Q000627:therapeutic use; D003802:Dentifrices / Q000494:pharmacology / Q000627:therapeutic use*; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000188:drug therapy*; D004338:Drug Combinations; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009566:Nitrates / Q000627:therapeutic use; D010710:Phosphates / Q000627:therapeutic use; D017680:Potassium Compounds / Q000627:therapeutic use; D011292:Premedication; D011897:Random Allocation; D012824:Silicic Acid / Q000009:adverse effects; D018709:Statistics, Nonparametric; D013997:Time Factors; D014073:Tooth Bleaching / Q000009:adverse effects*; D058205:Tooth Bleaching Agents / Q000009:adverse effects; D014098:Toothache / Q000188:drug therapy*; D014100:Toothpastes / Q000009:adverse effects; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D045424:Complex Mixtures; D003802:Dentifrices; D057133:Dentin Desensitizing Agents; D004338:Drug Combinations; D009566:Nitrates; D010710:Phosphates; D017680:Potassium Compounds; C097427:Sensodyne; D058205:Tooth Bleaching Agents; D014100:Toothpastes; C444700:colgate sensitive; C546060:hydrated silica gel-based toothpaste; D012824:Silicic Acid; D005459:Fluorides