title: Regio- and stereocontrolled access to γ-boronated unsaturated amino esters and derivatives from (Z)-alkenyl 1,2-bis(boronates).
abstract: The Borono-Mannich reaction of (Z)-1-alkene-1,2-diboronic esters proceeded regioselectively at the terminal C-B bond to afford (E)-γ-boronated unsaturated amino esters in good yields. These compounds were then subjected to Suzuki couplings for the creation of diversely substituted olefinic amino acid systems. Several other functional transformations were also carried out to illustrate the synthetic utility of the Petasis products.
authors.affiliation: Institut des Sciences Chimiques de Rennes, UMR 6226 CNRS-Université de Rennes 1 , 263 Avenue du Général Leclerc, Campus de Beaulieu, Bâtiment 10A, 35042 Rennes Cedex, France.
authors.forename: Tailor
authors.initials: T
authors.lastname: Sridhar
authors.forename: Fabienne
authors.initials: F
authors.lastname: Berrée
authors.forename: Gangavaram V M
authors.initials: GV
authors.lastname: Sharma
authors.forename: Bertrand
authors.initials: B
authors.lastname: Carboni