title: Laggeric acid, a novel seco-eudesmane sesquiterpenoid from Laggera crispata.
abstract: Laggeric acid (1), a novel 4,5-seco-eudesmane sesquiterpene acid, along with 19 known compounds, was isolated from the MeOH extract of the whole plant of Laggera crispata. The structure of 1 was elucidated to be (4S,5S*,7R*,10R*)-4,5-seco-4,5-dihydroxy-11(13)-eudesmen-12-oic acid on the basis of spectroscopic analysis and a convenient Mosher's method.
authors.affiliation: a PLA 98th Hospital , Huzhou , 313000 , China.
authors.forename: Yi-Hua
authors.initials: YH
authors.lastname: Qiu
authors.forename: Yan-Fang
authors.initials: YF
authors.lastname: Yang
authors.forename: Jun-Ming
authors.initials: JM
authors.lastname: Tan
authors.forename: Chang-Heng
authors.initials: CH
authors.lastname: Tan
authors.forename: Jun
authors.initials: J
authors.lastname: Chang
mesh_terms: D019659:Asteraceae / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012717:Sesquiterpenes; D045787:Sesquiterpenes, Eudesmane / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: D004365:Drugs, Chinese Herbal; D012717:Sesquiterpenes; D045787:Sesquiterpenes, Eudesmane; C587303:laggeric acid