title: [Investigation of relationship between obstructive sleep apnea hypopnea syndrome and left ventricular hypertrophy].
abstract: OBJECTIVE
  The purpose of this study is to approach the impact of obstructive sleep apnea-hypopnea syndrome (OSAHS) on left ventricular hypertrophy (LVH), to see whether OSAHS is an independent risk factor of LVH.
  
  
  METHODS
  Chose patients with OSAHS or essential hypertension (EH) as the study group (78 cases) and subjects without OSAHS and EH as Normal control group (22 cases). The study group was divided into 4 groups according to the diseases of OSAHS and EH:EH group (26 cases), OSAHS group(25 cases) and EH + OSAHS group (27 cases). Body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), interventricular septum thickness in diastole (IVSd), left ventricular posterior wall thickness in diastole (LVPWd) etc were tested in all the subjects. Statistical analysis was carried out with software of SPSS 11. 5 for windows. One-way analysis of variance and multiple stepwise regression analysis were used to assess the statistical evaluation. P < 0.05 was considered statistically significant.
  
  
  RESULTS
  IVSd and LVPWd of the control group were lower than study groups (EH group, OSAHS group and EH + OSAHS group), and IVSd, LVPWd of the EH + OSAHS group were higher than that of the EH group and OSAHS group (P < 0.05). Stepwise regression analysis showed that only AHI and SBP entered the regression equation (P < 0.05), it means that AHI and SBP are independent risk factors of IVSd and LVPWd.
  
  
  CONCLUSIONS
  OSAHS and SBP are independent risk factors of LVH.
authors.affiliation: Department of Otolaryngology, Xiaolan People' s Hospital, Zhongshan of Guangdong Province, 528415, China.
authors.forename: Chaoqing
authors.initials: C
authors.lastname: Long
authors.affiliation: Department of Otolaryngology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou.
authors.forename: Hua
authors.initials: H
authors.lastname: Zou
authors.affiliation: Department of Otolaryngology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou.
authors.forename: Qian
authors.initials: Q
authors.lastname: Cai
authors.affiliation: Department of Otolaryngology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou.
authors.forename: Yiqing
authors.initials: Y
authors.lastname: Zheng
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology; D017379:Hypertrophy, Left Ventricular / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications*