title: Eumycetoma by Madurella mycetomatis with 30 years of evolution: therapeutic challenge.
abstract: We report a case of eumycetoma by Madurella mycetomatis on the buttocks and thighs in an adult immunocompetent patient, diagnosed after 30 years of clinical development. He was treated over four years with fluconazol and itraconazol associated with five times surgical excisions of subcutaneous nodules. At the eighth year of follow-up, one nodule recurred on the right infragluteal region, which was excised surgically and has remained asymptomatic ever since.
authors.affiliation: Army Central Hospital, Tropical Dermatology Service, Rio de JaneiroRJ, Brazil.
authors.forename: Felipe Maurício Soeiro
authors.initials: FM
authors.lastname: Sampaio
authors.affiliation: Oswaldo Cruz Foundation, Evandro Chagas Research Institute, Laboratory of Dermatology in Infectious Diseases, Rio de JaneiroRJ, Brazil.
authors.forename: Maria Clara Gutierrez
authors.initials: MC
authors.lastname: Galhardo
authors.affiliation: Oswaldo Cruz Foundation, Evandro Chagas Clinical Research Institute, Department of Anatomic Pathology, Rio de JaneiroRJ, Brazil.
authors.forename: Leonardo Pereira
authors.initials: LP
authors.lastname: Quintella
authors.affiliation: Federal Hospital of Bonsucesso, Dermatology Service, Rio de Janeiro, Brazil.
authors.forename: Paulo Roberto Cotrim de
authors.initials: PR
authors.lastname: Souza
authors.affiliation: Oswaldo Cruz Foundation, Evandro Chagas Clinical Research Institute, Department of Anatomic Pathology, Rio de Janeiro, Brazil.
authors.forename: Janice Mary Chicarino de Oliveira
authors.initials: JM
authors.lastname: Coelho
authors.affiliation: Oswaldo Cruz Foundation, Evandro Chagas Research Institute, Laboratory of Dermatology in Infectious Diseases, Rio de JaneiroRJ, Brazil.
authors.forename: Antonio Carlos Francesconi do
authors.initials: AC
authors.lastname: Valle
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001706:Biopsy; D018450:Disease Progression; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D007121:Immunocompetence; D017964:Itraconazole / Q000627:therapeutic use; D020461:Madurella; D008297:Male; D008875:Middle Aged; D008271:Mycetoma / Q000473:pathology / Q000628:therapy*; D012008:Recurrence; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D015725:Fluconazole