title: Medicine. A common pathway for a rare disease?
authors.affiliation: Howard Hughes Medical Institute, Departments of Molecular Biology and Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
authors.forename: Scott B
authors.initials: SB
authors.lastname: Vafai
authors.forename: Vamsi K
authors.initials: VK
authors.lastname: Mootha
mesh_terms: D000818:Animals; D007888:Leigh Disease / Q000188:drug therapy*; D000076222:Mechanistic Target of Rapamycin Complex 1; D028361:Mitochondrial Diseases / Q000188:drug therapy*; D058990:Molecular Targeted Therapy; D046912:Multiprotein Complexes / Q000037:antagonists & inhibitors*; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D020123:Sirolimus / Q000627:therapeutic use*; D058570:TOR Serine-Threonine Kinases / Q000037:antagonists & inhibitors*
chemical_list: D046912:Multiprotein Complexes; D018696:Neuroprotective Agents; C546843:mTOR protein, mouse; D000076222:Mechanistic Target of Rapamycin Complex 1; D058570:TOR Serine-Threonine Kinases; D020123:Sirolimus