title: Lymphocyte recovery and infused CD34+ cells dose: Effect on the evolution after stem cell autotransplantation.
abstract: OBJECTIVE
  The number of infused CD34+cells (CD34+i) has been associated with absolute lymphocyte count (ALC) and the outcome undergoing autologous hematopoietic stem cell transplantation (HSCT) in patients with hematologic malignancies. The study's aim was to analyze the relationship between CD34+i, ALC and prognosis in this patients.
  
  
  METHODS
  Medical records of 163 patients receiving HSCT between 2005 and 2012 were reviewed.
  
  
  RESULTS
  We found significant and inversely proportional relationship between the CD34+i and the days required to reach ALC≥500/μl according to the regression line: days=-0.981×number of CD34+i+18.09.
  
  
  CONCLUSIONS
  We have obtained a predictive model of lymphocyte recovery based recovery of CD34+i.
authors.affiliation: Hematology Department, University Hospital La Paz, Paseo de la Castellana 261, C. P. 28046 Madrid, Spain.
authors.forename: Esperanza
authors.initials: E
authors.lastname: Romero Fernández
authors.affiliation: Hematology Department, University Hospital La Paz, Paseo de la Castellana 261, C. P. 28046 Madrid, Spain.
authors.forename: Guillermo Montalbán
authors.initials: GM
authors.lastname: Bravo
authors.affiliation: Hematology Department, University Hospital La Paz, Paseo de la Castellana 261, C. P. 28046 Madrid, Spain.
authors.forename: Rosario Arrieta
authors.initials: RA
authors.lastname: Gallastegui
authors.affiliation: Hematology Department, University Hospital La Paz, Paseo de la Castellana 261, C. P. 28046 Madrid, Spain.
authors.forename: Ana Rodríguez
authors.initials: AR
authors.lastname: De la Rúa Fernández
keywords: Infused CD34+ cells; Inmune reconstitution; Lymphocyte recovery; Prognosis; Stem cell autotransplantation