title: Antibacterial anthranilic acid derivatives from Geijera parviflora.
abstract: Five anthranilic acid derivatives, a mixture I of three new compounds 11'-hexadecenoylanthranilic acid (1), 9'-hexadecenoylanthranilic acid (2), and 7'-hexadecenoylanthranilic acid (3), as well as a new compound 9,12,15-octadecatrienoylanthranilic acid (4) together with a new natural product, hexadecanoylanthranilic acid (5), were isolated from Geijera parviflora Lindl. (Rutaceae). Their structures were elucidated by extensive spectroscopic measurements, and the positions of the double bonds in compounds 1-3 of the mixture I were determined by tandem mass spectrometry employing ozone-induced dissociation. The mixture I and compound 5 showed good antibacterial activity against several Gram-positive strains.
authors.affiliation: Southern Cross Plant Science, Southern Cross University, PO Box 157, Lismore, NSW 2480, Australia. Electronic address: qingyao.shou@scu.edu.au.
authors.forename: Qingyao
authors.initials: Q
authors.lastname: Shou
authors.affiliation: Southern Cross Plant Science, Southern Cross University, PO Box 157, Lismore, NSW 2480, Australia. Electronic address: linda.banbury@scu.edu.au.
authors.forename: Linda K
authors.initials: LK
authors.lastname: Banbury
authors.affiliation: School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia. Electronic address: alan_maccarone@uow.edu.au.
authors.forename: Alan T
authors.initials: AT
authors.lastname: Maccarone
authors.affiliation: Southern Cross Plant Science, Southern Cross University, PO Box 157, Lismore, NSW 2480, Australia. Electronic address: dane.renshaw@scu.edu.au.
authors.forename: Dane E
authors.initials: DE
authors.lastname: Renshaw
authors.affiliation: Ian Wark Research Institute, University of South Australia, Mawson Lakes, SA 5095, Australia. Electronic address: htwe.mon@mymail.unisa.edu.au.
authors.forename: Htwe
authors.initials: H
authors.lastname: Mon
authors.affiliation: Ian Wark Research Institute, University of South Australia, Mawson Lakes, SA 5095, Australia. Electronic address: stefani.griesser@unisa.edu.au.
authors.forename: Stefani
authors.initials: S
authors.lastname: Griesser
authors.affiliation: Ian Wark Research Institute, University of South Australia, Mawson Lakes, SA 5095, Australia. Electronic address: hans.griesser@unisa.edu.au.
authors.forename: Hans J
authors.initials: HJ
authors.lastname: Griesser
authors.affiliation: School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia. Electronic address: blanksby@uow.edu.au.
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Blanksby
authors.affiliation: Southern Cross Plant Science, Southern Cross University, PO Box 157, Lismore, NSW 2480, Australia. Electronic address: joshua.smith@scu.edu.au.
authors.forename: Joshua E
authors.initials: JE
authors.lastname: Smith
authors.affiliation: Division of Research, Southern Cross University, PO Box 157, Lismore, NSW 2480, Australia. Electronic address: hans.wohlmuth@scu.edu.au.
authors.forename: Hans
authors.initials: H
authors.lastname: Wohlmuth
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D027821:Rutaceae / Q000737:chemistry*; D062367:ortho-Aminobenzoates / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D062367:ortho-Aminobenzoates; C031385:anthranilic acid
keywords: Anthranilic acid derivative; Antibacterial activity; Geijera parviflora; Rutaceae