title: Transcription factor-mediated cell-to-cell signalling in plants.
abstract: Plant cells utilize mobile transcription factors to transmit intercellular signals when they perceive environmental stimuli or initiate developmental programmes. Studies on these novel cell-to-cell signals have accumulated multiple pieces of evidence showing that non-cell-autonomous transcription factors play pivotal roles in most processes related to the formation and development of plant organs. Recent studies have explored the evolution of mobile transcription factors and proposed mechanisms for their trafficking through plasmodesmata, where a selective system exists to facilitate this process. Mobile transcription factors contribute to the diversity of the intercellular signalling network, which is also established by peptides, hormones, and RNAs. Crosstalk between mobile transcription factors and other intercellular molecules leads to the development of complex biological signalling networks in plants. The regulation of plasmodesmata appears to have been another major step in controlling the intercellular trafficking of transcription factors based on studies of many plasmodesmal components. Furthermore, diverse omics approaches are being successfully applied to explore a large number of candidate transcription factors as mobile signals in plants. Here, we review these fascinating discoveries to integrate current knowledge of non-cell-autonomous transcription factors.
authors.affiliation: Division of Applied Life Science (BK21plus/WCU Program), Graduate School of Gyeongsang National University, Plant Molecular Biology & Biotechnology Research Center (PMBBRC), Jinju 660-701, Korea.
authors.forename: Xiao
authors.initials: X
authors.lastname: Han
authors.forename: Dhinesh
authors.initials: D
authors.lastname: Kumar
authors.forename: Huan
authors.initials: H
authors.lastname: Chen
authors.forename: Shuwei
authors.initials: S
authors.lastname: Wu
authors.forename: Jae-Yean
authors.initials: JY
authors.lastname: Kim
mesh_terms: D005075:Biological Evolution; D002450:Cell Communication; D063245:Plant Development; D010940:Plant Proteins / Q000235:genetics* / Q000378:metabolism; D010944:Plants / Q000235:genetics*; D031425:Plasmodesmata / Q000378:metabolism; D015398:Signal Transduction; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism*
chemical_list: D010940:Plant Proteins; D014157:Transcription Factors
keywords: Cell-to-cell communication; intercellular signalling; non-cell-autonomous proteins; plasmodesmata; transcription factors.