title: A case of endometrial cancer in the context of a BRCA2 mutation and double heterozygosity for Lynch syndrome.
abstract: ► Endometrial cancer with BRCA2 mutation and double heterozygosity for Lynch syndrome. ► Loss of MLH1 and PMS2 by immunohistochemical stain. ► MSH1 and MSH6 gene mutations by genomic sequencing.
authors.affiliation: Department of Pathology, Thomas Jefferson University Hospital, Philadelphia, PA, United States.
authors.forename: Ping
authors.initials: P
authors.lastname: Gong
authors.affiliation: Kimmel Cancer Center, Thomas Jefferson University Hospital, Philadelphia, PA, United States.
authors.forename: Sarah
authors.initials: S
authors.lastname: Charles
authors.affiliation: Gynecologic Oncology, Thomas Jefferson University Hospital, Philadelphia, PA, United States.
authors.forename: Norman
authors.initials: N
authors.lastname: Rosenblum
authors.affiliation: Department of Pathology, Thomas Jefferson University Hospital, Philadelphia, PA, United States.
authors.forename: Zoe
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Pathology, Thomas Jefferson University Hospital, Philadelphia, PA, United States.
authors.forename: Agnieszka K
authors.initials: AK
authors.lastname: Witkiewicz
keywords: BRCA2 mutation; Double heterozygosity; Endometrial cancer; Lynch syndrome