title: Rhodium(III)-catalyzed ortho alkenylation of N-phenoxyacetamides with N-tosylhydrazones or diazoesters through C-H activation.
abstract: A coupling reaction of N-phenoxyacetamides with N-tosylhydrazones or diazoesters through Rh(III) -catalyzed CH activation is reported. In this reaction, ortho-alkenyl phenols were obtained in good yields and with excellent regio- and stereoselectivity. Rh-carbene migratory insertion is proposed as the key step in the reaction mechanism.
authors.affiliation: Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871 (China); School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100 (China).
authors.forename: Fangdong
authors.initials: F
authors.lastname: Hu
authors.forename: Ying
authors.initials: Y
authors.lastname: Xia
authors.forename: Fei
authors.initials: F
authors.lastname: Ye
authors.forename: Zhenxing
authors.initials: Z
authors.lastname: Liu
authors.forename: Chen
authors.initials: C
authors.lastname: Ma
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jianbo
authors.initials: J
authors.lastname: Wang
keywords: CH activation; diazo compounds; homogeneous catalysis; metal-carbene complexes; migratory insertion