title: Evaluation of intercalated α-zirconium phosphate as sorbent in separation and detection of sulfonamides in honey.
abstract: This paper presented a simple and effective solid-phase extraction method using α-zirconium phosphate intercalated by hexadecyl trimethyl ammonium bromide (α-ZrP-CTMAB) as a novel adsorbent. Surfactant-assisted method was applied to prepare α-ZrP-CTMAB whose sorbent properties and extraction efficiency were investigated. Four sulfonamides (SAs) in honey were selected as analytical models and finally determined by liquid chromatography-tandem mass spectrometry. The recoveries of SAs at three spiked levels (10, 100, 1000ngg(-1)) were in the range of 58.7-99.3% and the relative standard deviations ranged from 2.69% to 7.48%. The detection limits obtained were 0.25-0.5ngg(-1). Compared with other methods in the literatures, the proposed method reduced the consumption of organic solvents and simplified the sample preparation procedure for the analysis of SAs in honey. Therefore, modified α-ZrP showed great potential in the analysis of pollutants in complex samples.
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, PR China.
authors.forename: Juan
authors.initials: J
authors.lastname: Hou
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, PR China.
authors.forename: Jin
authors.initials: J
authors.lastname: Yan
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, PR China.
authors.forename: Fengshuang
authors.initials: F
authors.lastname: Zhang
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, PR China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhao
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, PR China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Chen
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, PR China.
authors.forename: Yiqun
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, PR China.
authors.forename: Guijie
authors.initials: G
authors.lastname: Li
authors.affiliation: State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, PR China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Li
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, PR China. Electronic address: dinglan@jlu.edu.cn.
authors.forename: Lan
authors.initials: L
authors.lastname: Ding
mesh_terms: D000327:Adsorption; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification; D001516:Bees; D002853:Chromatography, Liquid; D004350:Drug Residues / Q000737:chemistry* / Q000302:isolation & purification; D005506:Food Contamination / Q000032:analysis*; D006722:Honey / Q000032:analysis*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D013449:Sulfonamides / Q000737:chemistry* / Q000302:isolation & purification; D053719:Tandem Mass Spectrometry; D015040:Zirconium / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D013449:Sulfonamides; C027006:zirconium phosphate; D015040:Zirconium
keywords: Honey; LC/MS–MS; Solid-phase extraction; Sulfonamides; Zirconium phosphate