title: Definitive radiotherapy for cervical esophageal cancer.
abstract: BACKGROUND
  The role of contemporary radiotherapy (RT) has not yet been elucidated, mainly because of the low incidence of cervical esophageal cancer. The purpose of this study was to analyze the outcome in patients with cervical esophageal cancer treated with definitive RT.
  
  
  METHODS
  A total of 115 patients with cervical esophageal cancer treated with definitive RT during January 2001 through April 2012 in our center were analyzed. Eighty patients received RT alone and 35 patients received concurrent chemoradiotherapy with cisplatin administered either weekly (30 mg/m2) or every 3 weeks (80 mg/m2).
  
  
  RESULTS
  The median follow-up time was 17.1 months. For all patients, the overall 2-year local failure-free survival (LFFS), regional failure-free survival (RFFS), distant failure-free survival (DFFS), and overall survival (OS) rate was 68.3%, 83.3%, 75.7%, and 47.6%, respectively.
  
  
  CONCLUSIONS
  Definitive RT accomplished a satisfactory local control rate and contributed to organ preservation for patients with cervical esophageal cancer. 2015.
authors.affiliation: Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, People's Republic of China.
authors.forename: Caineng
authors.initials: C
authors.lastname: Cao
authors.forename: Jingwei
authors.initials: J
authors.lastname: Luo
authors.forename: Li
authors.initials: L
authors.lastname: Gao
authors.forename: Guozhen
authors.initials: G
authors.lastname: Xu
authors.forename: Junlin
authors.initials: J
authors.lastname: Yi
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Huang
authors.forename: Kai
authors.initials: K
authors.lastname: Wang
authors.forename: Shiping
authors.initials: S
authors.lastname: Zhang
authors.forename: Yuan
authors.initials: Y
authors.lastname: Qu
authors.forename: Suyan
authors.initials: S
authors.lastname: Li
authors.forename: Jianping
authors.initials: J
authors.lastname: Xiao
authors.forename: Zhong
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D059248:Chemoradiotherapy; D018572:Disease-Free Survival; D004938:Esophageal Neoplasms / Q000401:mortality* / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D059351:Organ Sparing Treatments; D011379:Prognosis; D011879:Radiotherapy Dosage
keywords: cervical esophageal cancer; organ preservation; radiotherapy; survival; treatment