title: Science to Practice: can we diagnose nonalcoholic steatohepatitis with intravoxel incoherent motion diffusion-weighted MR imaging?
abstract: By showing that intravoxel incoherent motion parameters at diffusion-weighted magnetic resonance (MR) imaging may be indicators of the microcirculatory changes in patients with nonalcoholic steatohepatitis and fatty liver disease, Joo et al have taken a step forward in the validation of quantitative MR imaging parameters as biomarkers of nonalcoholic steatohepatitis and fatty liver disease. Further steps, including standardization, validation, and multiparametric imaging, must be taken before these parameters can be used as biomarkers in clinical practice.
authors.affiliation: IPMA Laboratory, U773 INSERM University Paris Diderot, Sorbonne Paris Cité Department of Radiology Beaujon University Hospital Paris Nord 100 Boulevard du General Leclerc 92110 Clichy, France.
authors.forename: Bernard E
authors.initials: BE
authors.lastname: Van Beers
mesh_terms: D015415:Biomarkers / Q000032:analysis; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005234:Fatty Liver / Q000175:diagnosis*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D065626:Non-alcoholic Fatty Liver Disease
chemical_list: D015415:Biomarkers