title: 3D versus 2D Systematic Transrectal Ultrasound-Guided Prostate Biopsy: Higher Cancer Detection Rate in Clinical Practice.
abstract: Objectives. To compare prostate cancer detection rates of extended 2D versus 3D biopsies and to further assess the clinical impact of this method in day-to-day practice. Methods. We analyzed the data of a cohort of 220 consecutive patients with no prior history of prostate cancer who underwent an initial prostate biopsy in daily practice due to an abnormal PSA and/or DRE using, respectively, the classical 2D and the new 3D systems. All the biopsies were done by a single experienced operator using the same standardized protocol. Results. There was no significant difference in terms of age, total PSA, or prostate volume between the two groups. However, cancer detection rate was significantly higher using the 3D versus the 2D system, 50% versus 34% (P < 0.05). There was no statistically significant difference while comparing the 2 groups in term of nonsignificant cancer detection. Conclusion. There is reasonable evidence demonstrating the superiority of the 3D-guided biopsies in detecting prostate cancers that would have been missed using the 2D extended protocol.
authors.affiliation: Department of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, Belgium ; Université Libre de Bruxelles, 50 Franklin Roosevelt Avenue, 1050 Brussels, Belgium.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Peltier
authors.affiliation: Department of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, Belgium ; Université Libre de Bruxelles, 50 Franklin Roosevelt Avenue, 1050 Brussels, Belgium.
authors.forename: Fouad
authors.initials: F
authors.lastname: Aoun
authors.affiliation: Department of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, Belgium.
authors.forename: Fouad
authors.initials: F
authors.lastname: El-Khoury
authors.affiliation: Department of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, Belgium.
authors.forename: Eric
authors.initials: E
authors.lastname: Hawaux
authors.affiliation: Department of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, Belgium.
authors.forename: Ksenija
authors.initials: K
authors.lastname: Limani
authors.affiliation: Department of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, Belgium.
authors.forename: Krishna
authors.initials: K
authors.lastname: Narahari
authors.affiliation: Department of Anatomopathology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, Belgium.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Sirtaine
authors.affiliation: Department of Urology, Jules Bordet Institute, 1 Rue Héger-Bordet, 1000 Brussels, Belgium ; Université Libre de Bruxelles, 50 Franklin Roosevelt Avenue, 1050 Brussels, Belgium.
authors.forename: Roland
authors.initials: R
authors.lastname: van Velthoven