title: An in vitro study on effect of Delmopinol application on Candida albicans adherence on heat cured denture base acrylic resin: a thorough study.
abstract: BACKGROUND
  Denture-related stomatitis is probably the most common form of oral candidiasis and its reported prevalence varies widely ranging up to 65%. In this thorough study, we evaluate the effect of Delmopinol application on Candida albicans adherence on heat cured denture base acrylic resin.
  
  
  METHODS
  A total of 40 specimens of heat-cured acrylic resin were made, 20 specimens were contaminated before Delmopinol treatment and 20 specimens were contaminated after Delmopinol treatment. The each specimen in each tube was individually transferred to a spectrophotometer at 530 nm wavelength in order to measure the turbidity degree, through the transmittance. Aliquots of 10 μL of each tube was then collected and inoculated into agar sabouraud plates containing 500 mMol/L of sucrose, which was incubated for 24 hours at 37°C, in order to check microbial growth.
  
  
  RESULTS
  Mean of the turbidity Degree of contamination after Delmopinol application (1440.80, colony-forming unit [CFU] [×10 6 /ml]) was significantly higher than the mean of the turbidity degree of contamination before Delmopinol application (550.85 CFU [×10 6 /ml]).
  
  
  CONCLUSIONS
  Heat-cured acrylic resin shows greater reduction in adherence of Candida albicans by contamination after Delmopinol application as compared with contamination before Delmopinol application.
authors.affiliation: Department of Prosthodontics, Government College of Dentistry, Indore, Madhya Pradesh, India.
authors.forename: Deshraj
authors.initials: D
authors.lastname: Jain
authors.forename: Prabha
authors.initials: P
authors.lastname: Shakya
mesh_terms: D000180:Acrylic Resins; D002176:Candida albicans / Q000187:drug effects* / Q000502:physiology; D003819:Denture Bases; D006358:Hot Temperature; D066298:In Vitro Techniques; D009025:Morpholines / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D000180:Acrylic Resins; D009025:Morpholines; C073738:delmopinol