title: Relation of ABO blood groups to coronary lesion complexity in patients with stable coronary artery disease.
abstract: OBJECTIVE
  We aimed to investigate the relationship between ABO blood groups and complexity of coronary lesions assessed by SYNTAX score (SS) in stable coronary artery disease (CAD) patients.
  
  
  METHODS
  Our cross-sectional and observational study population consisted of 559 stable CAD patients. From all patients, ABO blood group was determined and the SS was calculated as low SYNTAX score (0-22), intermediate SYNTAX (23-32) score and high SYNTAX score (>32). Statistical analysis was performed using Student's t-test or Mann-Whitney U test, ANOVA, or Kruskal-Wallis test and chi-square test. Multiple logistic regression analysis was used to identify the independent predictors of high SS.
  
  
  RESULTS
  The analysis between the SS tertiles revealed that the frequency of non-O blood group was significantly higher in the upper SS tertiles (56.2% vs. 75.9 vs. 80.2%, p<0.05). However, the frequencies of Rh types were similar in all tertiles. Multiple logistic regression analysis was applied for determining the predictors of high SS. Accordingly, non-O blood group (OR: 2.68, 95% CI 1.65-4.35, p<0.001), LV-EF (OR: 0.93, 95% CI 0.91-0.95, p<0.001), LDL(OR: 0.98, 95% CI 0.97-0.99, p<0.001), and e-GFR (OR: 0.99, 95% CI 0.98-0.98, p<0.001) were found to be the independent predictors of high SS.
  
  
  CONCLUSIONS
  We showed that there were significant associations between ABO blood groups and complexity of angiographic CAD.
authors.affiliation: Department of Cardiology, Faculty of Medicine, Ordu University; Ordu-Turkey. doktorahmetkaya@yahoo.com.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kaya
authors.forename: İbrahim Halil
authors.initials: İH
authors.lastname: Tanboğa
authors.forename: Mustafa
authors.initials: M
authors.lastname: Kurt
authors.forename: Turgay
authors.initials: T
authors.lastname: Işık
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Kaya
authors.forename: Zeki Yüksel
authors.initials: ZY
authors.lastname: Günaydın
authors.forename: Enbiya
authors.initials: E
authors.lastname: Aksakal
mesh_terms: D000017:ABO Blood-Group System; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000097:blood* / Q000000981:diagnostic imaging / Q000473:pathology; D003430:Cross-Sectional Studies; D006801:Humans; D016015:Logistic Models; D012720:Severity of Illness Index
chemical_list: D000017:ABO Blood-Group System