title: The pertussis problem.
abstract: Pertussis is resurgent, and many cases are occurring in vaccinated children and adolescents. In countries using acellular vaccines, waning immunity is at least part of the problem. This article discusses possible improvements in those vaccines.
authors.affiliation: Department of Pediatrics, University of Pennsylvania, Philadelphia.
authors.forename: Stanley A
authors.initials: SA
authors.lastname: Plotkin
mesh_terms: D000907:Antibodies, Bacterial / Q000276:immunology; D006801:Humans; D037342:Pertussis Toxin / Q000276:immunology; D010567:Pertussis Vaccine / Q000008:administration & dosage* / Q000276:immunology; D014917:Whooping Cough / Q000276:immunology* / Q000517:prevention & control*
chemical_list: D000907:Antibodies, Bacterial; D010567:Pertussis Vaccine; D037342:Pertussis Toxin
keywords: Th1 responses; adjuvants; pertussis; pertussis toxin; waning immunity