title: The effects of a single dialysis session on atrial electromechanical conduction times and functions.
abstract: OBJECTIVE
  Abnormalities in atrial electromechanical delay (EMD) times and mechanical functions are considered as independent predictors of atrial fibrillation. However, to date, effects of a single hemodialysis (HD) session and acute volume-preload changes on atrial-EMD functions have not been investigated by Tissue Doppler Echocardiography (TDE). The aim of the present study was to evaluate atrial-EMD times and mechanical functions in HD patients.
  
  
  METHODS
  Thirty-five non-diabetic, normotensive HD patients and 35 healthy control subjects were enrolled in the study. Standard and TDE performed before mid-week dialysis session for hemodialysis group and on admission for control group.
  
  
  RESULTS
  Interatrial and left-right intraatrial-EMD intervals and left atrial mechanical volumes were significantly longer in hemodialysis group compared to controls (all p<0.01) and were reduced after HD session. Furthermore, removed ultrafiltration volume was associated with reduction in atrial-EMD intervals and functional volumes. LA-passive emptying volume, ultrafiltration volume, LV-E/E' ratio, and Vp were independent predictors of interatrial-EMD.
  
  
  CONCLUSIONS
  The present study confirms negative effects in HD patients of structural remodeling and reveals negative effects of electrical remodeling. Prolonged inter and intraatrial-EMD intervals should be the underlying pathophysiological factors of increased rate of atrial fibrillation in the HD population.
authors.affiliation: Department of Nephrology, AIB University Hospital, 14280 Bolu, Turkey.
authors.forename: Hikmet
authors.initials: H
authors.lastname: Tekce
authors.forename: Serkan
authors.initials: S
authors.lastname: Ozturk
authors.forename: Gulali
authors.initials: G
authors.lastname: Aktas
authors.forename: Buket Kin
authors.initials: BK
authors.lastname: Tekce
authors.forename: Alim
authors.initials: A
authors.lastname: Erdem
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ozyasar
authors.forename: Tuba Taslamacıoglu
authors.initials: TT
authors.lastname: Duman
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yazici
mesh_terms: D000328:Adult; D016275:Atrial Function / Q000502:physiology*; D001696:Biomechanical Phenomena / Q000502:physiology; D015331:Cohort Studies; D015150:Echocardiography, Doppler / Q000379:methods; D005260:Female; D006325:Heart Atria / Q000000981:diagnostic imaging*; D006329:Heart Conduction System / Q000000981:diagnostic imaging* / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D006435:Renal Dialysis / Q000009:adverse effects* / Q000379:methods; D013997:Time Factors; D016896:Treatment Outcome