title: Detection of the ovarian cancer biomarker CA-125 using chemiluminescence resonance energy transfer to graphene quantum dots.
abstract: An immunoassay has been developed for the detection of the ovarian cancer biomarker CA-125 by utilizing the chemiluminescence resonance energy transfer to graphene quantum dots. This biosensor shows a wide linear range from 0.1 U mL(-1) to 600 U mL(-1) with a limit of detection of 0.05 U mL(-1) for CA-125 in a buffer solution.
authors.affiliation: Department of Biotechnology, College of Science, University of Baghdad, Baghdad, Iraq.
authors.forename: Israa
authors.initials: I
authors.lastname: Al-Ogaidi
authors.forename: Honglei
authors.initials: H
authors.lastname: Gou
authors.forename: Zoraida P
authors.initials: ZP
authors.lastname: Aguilar
authors.forename: Shouwu
authors.initials: S
authors.lastname: Guo
authors.forename: Alice K
authors.initials: AK
authors.lastname: Melconian
authors.forename: Abdul Kareem A
authors.initials: AK
authors.lastname: Al-Kazaz
authors.forename: Fanke
authors.initials: F
authors.lastname: Meng
authors.forename: Nianqiang
authors.initials: N
authors.lastname: Wu
mesh_terms: D000906:Antibodies / Q000737:chemistry / Q000276:immunology; D015374:Biosensing Techniques; D018394:CA-125 Antigen / Q000032:analysis* / Q000276:immunology; D004735:Energy Transfer; D005260:Female; D006108:Graphite / Q000737:chemistry; D006735:Horseradish Peroxidase / Q000737:chemistry; D006801:Humans; D006861:Hydrogen Peroxide / Q000737:chemistry; D007118:Immunoassay / Q000379:methods; D049449:Luminescence; D008163:Luminescent Measurements; D010051:Ovarian Neoplasms; D045663:Quantum Dots / Q000737:chemistry
chemical_list: D000906:Antibodies; D018394:CA-125 Antigen; D006108:Graphite; D006861:Hydrogen Peroxide; D006735:Horseradish Peroxidase