title: Total synthesis of ellipticine quinones, olivacine, and calothrixin B.
abstract: A direct route to the synthesis of biologically active ellipticine quinones, olivacine, and calothrixin B is described. The prominent key steps involved are Friedel-Crafts hydroxyalkylation followed by oxidation and directed ortho-lithiation reactions of readily available indole-2-carboxylate esters with appropriately substituted pyridine and quinoline carboxaldehydes.
authors.affiliation: School of Chemistry, University of Hyderabad , Hyderabad 500 046, India.
authors.forename: Nagarajan
authors.initials: N
authors.lastname: Ramkumar
authors.forename: Rajagopal
authors.initials: R
authors.lastname: Nagarajan
mesh_terms: D004611:Ellipticines / Q000138:chemical synthesis* / Q000737:chemistry; D026121:Indole Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011809:Quinones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D004611:Ellipticines; D026121:Indole Alkaloids; D011809:Quinones; C418327:calothrixin B