title: Treatment of recalcitrant facial verrucae vulgares with sinecatechins (greentea catechins) ointment.
abstract: BACKGROUND
  Facial verrucae vulgares are benign, but disfiguring skin manifestations of human papilloma virus infection. They are found as verrucae planae juveniles in young adults, but also as common warts in immunocompromised or atopic patients.
  
  
  OBJECTIVE
  To find an alternative, non-surgical treatment for a young man with atopic dermatitis and facial warts, who had not responded to 5-FU ointment, waterfiltered infrared A (wIRA) irradiation and topical retinoids.
  
  
  METHODS
  Topical treatment with a sinecatechins 10% ointment (Veregen(TM) ) as approved for genital warts thrice daily for 3 weeks in a 34-year-old man with atopic dermatitis
  
  
  RESULTS
  Complete remission of all facial warts was achieved within 20 days. Few side-effects were observed (initially some light skin irritation only).
  
  
  CONCLUSIONS
  In this case, topical sinecatechins proved to be a well-tolerated and effective alternative to treat recalcitrant facial warts without surgery.
authors.affiliation: Department of Dermatology, Venereology, and Allergology, J.W. Goethe University, Frankfurt/M, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Clouth
authors.forename: H
authors.initials: H
authors.lastname: Schöfer
mesh_terms: D000328:Adult; D028241:Camellia sinensis; D002392:Catechin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005148:Facial Dermatoses / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D008297:Male; D009824:Ointments / Q000627:therapeutic use; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D019233:Retreatment; D014860:Warts / Q000188:drug therapy*
chemical_list: D009824:Ointments; D010936:Plant Extracts; C527126:green tea extract polyphenone E; D002392:Catechin