title: Gene prioritization of resistant rice gene against Xanthomas oryzae pv. oryzae by using text mining technologies.
abstract: To effectively assess the possibility of the unknown rice protein resistant to Xanthomonas oryzae pv. oryzae, a hybrid strategy is proposed to enhance gene prioritization by combining text mining technologies with a sequence-based approach. The text mining technique of term frequency inverse document frequency is used to measure the importance of distinguished terms which reflect biomedical activity in rice before candidate genes are screened and vital terms are produced. Afterwards, a built-in classifier under the chaos games representation algorithm is used to sieve the best possible candidate gene. Our experiment results show that the combination of these two methods achieves enhanced gene prioritization.
authors.affiliation: College of Science, Huazhong Agricultural University, Wuhan 430070, Hubei, China ; Department of Chinese, Translation and Linguistics, City University of Hong Kong, Kowloon, Hong Kong.
authors.forename: Jingbo
authors.initials: J
authors.lastname: Xia
authors.affiliation: The Halliday Centre for Intelligent Applications of Language Studies, City University of Hong Kong, Kowloon, Hong Kong.
authors.forename: Xing
authors.initials: X
authors.lastname: Zhang
authors.affiliation: College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China.
authors.forename: Daojun
authors.initials: D
authors.lastname: Yuan
authors.affiliation: College of Life Science, Huazhong Agricultural University, Wuhan 430070, Hubei, China.
authors.forename: Lingling
authors.initials: L
authors.lastname: Chen
authors.affiliation: Department of Chinese, Translation and Linguistics, City University of Hong Kong, Kowloon, Hong Kong ; The Halliday Centre for Intelligent Applications of Language Studies, City University of Hong Kong, Kowloon, Hong Kong.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Webster
authors.affiliation: Department of Chinese, Translation and Linguistics, City University of Hong Kong, Kowloon, Hong Kong ; The Halliday Centre for Intelligent Applications of Language Studies, City University of Hong Kong, Kowloon, Hong Kong.
authors.forename: Alex Chengyu
authors.initials: AC
authors.lastname: Fang
mesh_terms: D000465:Algorithms; D057225:Data Mining; D056726:Genetic Association Studies; D012275:Oryza / Q000235:genetics* / Q000382:microbiology; D014974:Xanthomonas / Q000235:genetics / Q000472:pathogenicity*