title: Peanut allergen in house dust of eating area and bed--a risk factor for peanut sensitization?
abstract: It has been hypothesized that high environmental exposure to peanut allergens may be a potent risk factor for cutaneous sensitization. Therefore, we wanted to investigate whether peanut proteins are detectable in house dust of different household areas. Peanut levels of dust samples were measured with ELISA. Overall, peanut was detectable in 19 of 21 households in the eating area and/or in bed. The frequency of peanut consumption correlated with peanut levels. Forty-eight hours after intentional peanut consumption, peanut levels were highly increased. Nevertheless, further research is required to prove whether peanut allergen in house dust can cause sensitization via skin.
authors.affiliation: Department of Pediatric Pneumology and Immunology, Charité Universitätsmedizin, Berlin, Germany.
authors.forename: V
authors.initials: V
authors.lastname: Trendelenburg
authors.forename: B
authors.initials: B
authors.lastname: Ahrens
authors.forename: A-K
authors.initials: AK
authors.lastname: Wehrmann
authors.forename: B
authors.initials: B
authors.lastname: Kalb
authors.forename: B
authors.initials: B
authors.lastname: Niggemann
authors.forename: K
authors.initials: K
authors.lastname: Beyer
mesh_terms: D000485:Allergens / Q000276:immunology*; D010367:Arachis / Q000276:immunology*; D001513:Beds; D004391:Dust / Q000276:immunology*; D004435:Eating / Q000276:immunology*; D004781:Environmental Exposure; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D012307:Risk Factors
chemical_list: D000485:Allergens; D004391:Dust
keywords: cutaneous sensitization; environmental exposure; food allergens; house dust; peanut allergy