title: [Prevalence and risk factors for hepatitis B in Hua County, Henan Province].
abstract: OBJECTIVE
  To determine the epidemiological characteristics and associated risk factors of hepatitis B surface antigens (HBsAg) prevalence in rural areas of Hua County, Henan Province, and to provide scientific evidence for Hepatitis B prevention and control in local areas.
  
  
  METHODS
  On the basis of an ongoing esophageal cancer cohort study in rural Anyang, a total of 5 104 subjects aged 25-65 years were clustered and selected from 5 targeted villages for this study in rural areas of Hua County, Henan Province. HBsAg was detected in their blood samples and a questionnaire was completed by all the subjects in a manner of one-on-one interview. All statistical analyses were conducted using SPSS for Windows version 13.0.
  
  
  RESULTS
  Of the 5 104 studied subjects (overall participation rate: 92.05%), 5.17% were positive for HBsAg. The detection rate was significantly higher in males than in females (6.54% vs. 3.87%, P<0.001) and the highest detection rates were observed in the 25-29 and 55-59 years groups in both males and females. Multiple Logistic analyses showed unmarried status (OR=1.80, 95% CI: 1.00-3.25) and high frequency of sexual intercourse (Ptrend=0.049) were associated with higher the risk for hepatitis B virus (HBV) infection.
  
  
  CONCLUSIONS
  The prevalence of HBsAg in rural Hua County, Henan Province, was slightly lower than the national average of the same time period. More attention should be attached to high risk groups of HBV infection in this population, i.e. males aged 25-29 years and 55-59 years and sexually active population. Immunization and health education projects against hepatitis B should be carried out in this population to further reduce the overall prevalence of hepatitis B.
authors.affiliation: Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education; Laboratory of Genetics, Peking University Cancer Hospital & Institute, Beijing 100142, China.
authors.forename: Qiu-ju
authors.initials: QJ
authors.lastname: Deng
authors.forename: Ya-qi
authors.initials: YQ
authors.lastname: Pan
authors.affiliation: Hua County Bureau of Health, Henan Province, Anyang 456400, China.
authors.forename: Chao-yi
authors.initials: CY
authors.lastname: Wang
authors.affiliation: Hua County People's Hospital, Henan Province, Anyang 456400, China.
authors.forename: Feng-lei
authors.initials: FL
authors.lastname: Li
authors.forename: Shao-jiang
authors.initials: SJ
authors.lastname: Lv
authors.forename: Shao-yong
authors.initials: SY
authors.lastname: Hu
authors.forename: Tao
authors.initials: T
authors.lastname: Ning
authors.forename: Chuan-hai
authors.initials: CH
authors.lastname: Guo
authors.forename: Zhong-hu
authors.initials: ZH
authors.lastname: He
authors.forename: Yang
authors.initials: Y
authors.lastname: Ke
mesh_terms: D000328:Adult; D000367:Age Factors; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D003075:Coitus; D005260:Female; D006509:Hepatitis B / Q000097:blood / Q000453:epidemiology*; D006514:Hepatitis B Surface Antigens / Q000097:blood*; D006801:Humans; D008297:Male; D017533:Marital Status; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012424:Rural Population; D012737:Sex Factors; D012907:Smoking; D011795:Surveys and Questionnaires
chemical_list: D006514:Hepatitis B Surface Antigens