title: Is hypothyroidism and hypogonadism an issue after aneurysmal subarachnoid hemorrhage-an institutional experience?
abstract: BACKGROUND
  The incidence of hypopituitarism in aneurysmal subarachnoid hemorrhage ranges from 0% to 45%. Also the screening for hypopituitarism in survivors of aneurysmal SAH is not a routine. This has led to a controversy in the management of such patients.
  
  
  OBJECTIVE
  The aim of the study was to evaluate the endocrine profile of our patients who had presented with aneurysmal SAH.
  
  
  METHODS
  This was a prospective study conducted over a period of three years in patients of aneurysmal subarachnoid hemorrhage. The serum samples for levels of free T4, free T3, TSH, prolactin, FSH, LH and testosterone were analyzed at the time of admission and at a follow-up period between 9-12 months. Patients with known endocrine abnormalities, liver or kidney disease and patients with hemodynamic abnormalities were excluded from the study. Abnormalities in levels were noted and a comparative analysis of the hormone levels between the 2-time periods was done. A total of 73 patients were enrolled in the study.
  
  
  RESULTS
  Serum prolactin was raised in 17.80% (13/73) and FSH, LH and testosterone levels were reduced in 12.32% (9/73) of patients in the acute phase at admission. After 9 months follow-up, serum prolactin normalized in all except one patient and in all the males, testosterone level increased significantly. Two patients (3%) developed central hypothyroidism on follow-up.
  
  
  CONCLUSIONS
  Chronic hypothyroidism and hypogonadism is not an issue in aneurysmal SAH patients.
authors.affiliation: Department of Neurosurgery, Sheri-Kashmir Institute of Medical Sciences, Kashmir, India.
authors.forename: Nayil
authors.initials: N
authors.lastname: Khursheed
authors.affiliation: Department of Neurosurgery, Sheri-Kashmir Institute of Medical Sciences, Kashmir, India.
authors.forename: Altaf
authors.initials: A
authors.lastname: Ramzan
authors.affiliation: Department of Neurosurgery, Sheri-Kashmir Institute of Medical Sciences, Kashmir, India.
authors.forename: Yawar
authors.initials: Y
authors.lastname: Shoaib
authors.affiliation: Department of Endocrinology, Sheri-Kashmir Institute of Medical Sciences, Kashmir, India.
authors.forename: Iftikhar
authors.initials: I
authors.lastname: Bashir
authors.affiliation: Department of Neurosurgery, Sheri-Kashmir Institute of Medical Sciences, Kashmir, India.
authors.forename: Abrar
authors.initials: A
authors.lastname: Wani
authors.affiliation: Department of Neurosurgery, Sheri-Kashmir Institute of Medical Sciences, Kashmir, India.
authors.forename: Alam
authors.initials: A
authors.lastname: Shafiq
keywords: Hypogonadism; Hypothalamic Diseases; Hypothyroidism