title: Malignant transformation of intracranial epidermoid cyst.
abstract: Intracranial epidermoid cysts (ECs) are rare, histologically benign, slow-growing, congenital neoplasms of central nervous system that may arise from retained ectodermal implants. Malignant transformation of an EC to squamous-cell carcinoma is rare; only 13 cases have been reported. We present the case of a 42-year-old woman presenting with left hemiparesis 18 months after performing partial resection of an epidermoid cyst of right middle and posterior fossa, whose pathological report revealed to be a malignant transformation of previous epidermoid tumor. Additionally, we performed pertinent literature review.
authors.affiliation: Department of Neurosurgery, Hospital do Servidor Público Estadual de São Paulo, IAMSPE , São Paulo , Brazil.
authors.forename: Eduardo Arnaldo Silva
authors.initials: EA
authors.lastname: Vellutini
authors.forename: Matheus Fernandes
authors.initials: MF
authors.lastname: de Oliveira
authors.forename: Arthur Pedro Costa
authors.initials: AP
authors.lastname: Ribeiro
authors.forename: José Marcus
authors.initials: JM
authors.lastname: Rotta
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D002528:Cerebellar Neoplasms / Q000175:diagnosis / Q000601:surgery*; D002530:Cerebellopontine Angle / Q000473:pathology*; D004814:Epidermal Cyst / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D016896:Treatment Outcome
keywords: brain neoplasms; epidermoid; malignant transformation