title: Neurobehavioral effects of levetiracetam in patients with traumatic brain injury.
abstract: Moderate to severe traumatic brain injury (TBI) is one of the leading causes of acquired epilepsy. Prophylaxis for seizures is the standard of care for individuals with moderate to severe injuries at risk for developing seizures, though relatively limited comparative data is available to guide clinicians in their choice of agents. There have however been experimental studies which demonstrate potential neuroprotective qualities of levetiracetam after TBI, and in turn there is hope that eventually such agents may improve neurobehavioral outcomes post-TBI. This mini-review summarizes the available studies and suggests areas for future studies.
authors.affiliation: Department of Neurology, Scott & White Healthcare, Texas A&M Health Science Center College of Medicine , Temple, TX , USA.
authors.forename: Jared F
authors.initials: JF
authors.lastname: Benge
authors.affiliation: Department of Neurology, Scott & White Healthcare, Texas A&M Health Science Center College of Medicine , Temple, TX , USA.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Phenis
authors.affiliation: Department of Neurology, Scott & White Healthcare, Texas A&M Health Science Center College of Medicine , Temple, TX , USA.
authors.forename: Abigail
authors.initials: A
authors.lastname: Bernett
authors.affiliation: Department of Neurology, Scott & White Healthcare, Texas A&M Health Science Center College of Medicine , Temple, TX , USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Cruz-Laureano
authors.affiliation: Department of Neurology, Scott & White Healthcare, Texas A&M Health Science Center College of Medicine , Temple, TX , USA.
authors.forename: Batool F
authors.initials: BF
authors.lastname: Kirmani
keywords: levetiracetam; neurobehavioral effects; neurobehavioral outcomes; neurological functioning; traumatic brain injury