title: MRI brain in monohalomethane toxic encephalopathy: A case report.
abstract: Monohalomethanes are alkylating agents that have been used as methylating agents, laboratory reagents, refrigerants, aerosol propellants, pesticides, fumigants, fire-extinguishing agents, anesthetics, degreasers, blowing agents for plastic foams, and chemical intermediates. Compounds in this group are methyl chloride, methyl bromide, methyl iodide (MI), and methyl fluoride. MI is a colorless volatile liquid used as a methylating agent to manufacture a few pharmaceuticals and is also used as a fumigative insecticide. It is a rare intoxicant. Neurotoxicity is known with both acute and chronic exposure to MI. We present the characteristic magnetic resonance imaging (MRI) brain findings in a patient who developed neuropsychiatric symptoms weeks after occupational exposure to excessive doses of MI.
authors.affiliation: Department of Radiology, Star Imaging and Research Centre, Opp. Kamala Nehru Park, Joshi Hospital Campus, Erandwane, Pune, Maharashtra, India.
authors.forename: Yogeshwari S
authors.initials: YS
authors.lastname: Deshmukh
authors.affiliation: Department of Radiology, Star Imaging and Research Centre, Opp. Kamala Nehru Park, Joshi Hospital Campus, Erandwane, Pune, Maharashtra, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Atre
authors.affiliation: Department of Radiology, Star Imaging and Research Centre, Opp. Kamala Nehru Park, Joshi Hospital Campus, Erandwane, Pune, Maharashtra, India.
authors.forename: Darshan
authors.initials: D
authors.lastname: Shah
authors.affiliation: Neurology OPD, Poona Hospital and Research Centre, 27, Sadashiv Peth, Pune, Maharashtra, India.
authors.forename: Sudhir
authors.initials: S
authors.lastname: Kothari
keywords: MRI brain; Methyl iodide; toxic encephalopathy