title: Biochemical composition and antioxidant properties of Lavandula angustifolia Miller essential oil are shielded by propolis against UV radiations.
abstract: UV radiations are principal causes of skin cancer and aging. Suntan creams were developed to protect epidermis and derma layers against photodegradation and photooxidation. The addition of antioxidant plant extracts (i.e. essential oil) to sunscreens is habitually performed, to increase their UV protective effects and to contrast pro-radical and cytotoxic compounds present in these solutions. According to these observations, in the present work, the alteration of chemical composition and bioactive properties of Lavandula angustifolia Miller essential oil, exposed to UV light, was investigated. UV induced a significant deterioration of lavender oil biochemical profile. Moreover, the antioxidant activity of this solution, in in vitro tests and directly on B16-F10 melanoma cells, greatly decreased after UV treatment. Our results also showed that essential oil was shielded from UV stress by propolis addition. Even after UV treatment, bee glue highly protected lavender oil secondary metabolites from degradation and also preserved their antiradical properties, both in in vitro antioxidant assays and in cell oxidative damage evaluations. This research proposed propolis as highly efficient UV protective and antiradical additive for sunscreens, cosmetics and alimentary or pharmaceutical products containing plant extracts.
authors.forename: Angelo
authors.initials: A
authors.lastname: Gismondi
authors.affiliation: Department of Biology, University of Rome "Tor Vergata", Rome, Italy.
authors.forename: Gismondi
authors.initials: G
authors.lastname: Angelo
authors.forename: Lorena
authors.initials: L
authors.lastname: Canuti
authors.forename: Canuti
authors.initials: C
authors.lastname: Lorena
authors.forename: Marta
authors.initials: M
authors.lastname: Grispo
authors.forename: Grispo
authors.initials: G
authors.lastname: Marta
authors.forename: Antonella
authors.initials: A
authors.lastname: Canini
authors.forename: Canini
authors.initials: C
authors.lastname: Antonella
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D008401:Gas Chromatography-Mass Spectrometry; D027523:Lavandula / Q000737:chemistry*; D009822:Oils, Volatile / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D014466:Ultraviolet Rays
chemical_list: D000975:Antioxidants; D009822:Oils, Volatile; D010936:Plant Extracts