title: Dengue outbreaks: a constant risk for Reunion Island. Results from a seroprevalence study among blood donors.
abstract: BACKGROUND
  Immunity against dengue virus (DENV) on Reunion Island could play an important role in the risk of dengue outbreaks but is rather unknown. A study was performed to estimate seroprevalence of antibodies against DENV among blood donors.
  
  
  METHODS
  An age- and sex-stratified sample of 1825 sera was randomly selected.
  
  
  RESULTS
  Overall seroprevalence was 3.1% (95% CI: 2.2-3.9%); seroprevalence increased with age and was much higher in women than in men.
  
  
  CONCLUSIONS
  The low level of herd immunity is consistent with the absence of an endemic circulation of DENV, and makes it probable that Reunion Island will face future outbreaks.
authors.affiliation: Cire océan Indien (Cire OI), Institut de Veille Sanitaire (InVS), 97400 Saint Denis, Réunion, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Larrieu
authors.forename: Alain
authors.initials: A
authors.lastname: Michault
authors.forename: Dominique
authors.initials: D
authors.lastname: Polycarpe
authors.forename: François
authors.initials: F
authors.lastname: Schooneman
authors.forename: Eric
authors.initials: E
authors.lastname: D'Ortenzio
authors.forename: Laurent
authors.initials: L
authors.lastname: Filleul
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood; D001782:Blood Donors / Q000706:statistics & numerical data*; D003715:Dengue / Q000453:epidemiology*; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D016036:Seroepidemiologic Studies; D017678:Sex Distribution; D014900:West Indies / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral
keywords: Dengue; Outbreaks; Reunion Island; Risk; Seroprevalence