title: A case report of atypical scrotal leiomyoma.
abstract: Scrotal leiomyoma is a benign tumor derived from the scrotal dartos muscle; it is rare in clinical findings. The cause of the disease is not yet clear. Here, we present the case of a patient with no typical clinical features, but with some typical pathological changes. A middle-aged male patient saw a doctor for paroxysmal itching and burning of the scrotum. The physical examination revealed 3 × 5-cm(2), ill-defined, pink plaques, an uneven surface, and basal infiltration with pigmentation defects in the center. Pathology results showed dermal spindle cells in nodular hyperplasia. The nucleus was round at both ends, a perinuclear halo could be seen, and staining was positive for actin and negative for S100. Therefore, the diagnosis of scrotal myoma was made.
authors.affiliation: Dermatology Department, Zhongshan Urological Hospital of Shenzhen, Shenzhen, China.
authors.forename: Shu-Lin
authors.initials: SL
authors.lastname: Li
authors.affiliation: Department of Dermatology, The First Affiliated Hospital of Sun Yat-sen Hospital, Guangzhou, China.
authors.forename: Jian-De
authors.initials: JD
authors.lastname: Han
keywords: Actin; Leiomyoma of the scrotum; S100