title: Meta-cognitive beliefs as a mediator for the relationship between Cloninger's temperament and character dimensions and depressive and anxiety symptoms among healthy subjects.
abstract: BACKGROUND
  Previous studies suggest that temperament and character may impact depression and anxiety through dysfunctional cognition. This study targets the mediating role of meta-cognitive beliefs in the relationship between Cloninger's temperament and character dimensions and symptoms of depression and anxiety.
  
  
  METHODS
  One hundred and sixty-one healthy subjects filled out Cloninger's Temperament Character Inventory (TCI), a Metacognitions Questionnaire (MCQ), the Beck Depression Inventory (BDI) and the State and Trait Anxiety Inventory (STAI). Correlation and mediation analyses according to Baron and Kenny's method were performed.
  
  
  RESULTS
  Harm avoidance (HA) and self-directedness (SD) were related to depression and anxiety. HA was related to negative beliefs about uncontrollability of thoughts and to beliefs about cognitive confidence. SD was associated with the same types of meta-cognitive beliefs and with general negative beliefs. Cooperativeness (CO) was related to positive beliefs about worry, beliefs about cognitive confidence and to general negative beliefs. Self-transcendence (ST) was related to all types of meta-cognitive beliefs. Mediation analysis revealed that the relationship between HA and depression and anxiety is partially mediated by certain types of meta-cognitive beliefs. The same results were obtained for the relationship between SD and depression and anxiety. General negative beliefs fully mediated the relationship between CO and depression and the relationship between ST and anxiety.
  
  
  CONCLUSIONS
  Meta-cognitive beliefs mediate the relationship between temperament and character dimension and depressive and anxiety symptoms, thus providing further evidence for the meta-cognitive theory of emotional disorders as presented by Wells and Matthews (Behav Res Ther 1996;32:867-870).
authors.affiliation: II Department of Psychiatry, Medical University of Warsaw, Poland. Electronic address: lgaweda@wum.edu.pl.
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Gawęda
authors.affiliation: II Department of Psychiatry, Medical University of Warsaw, Poland; Warsaw School of Social Sciences and Humanities, Warsaw, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Kokoszka
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000523:psychology*; D002605:Character; D003071:Cognition; D003863:Depression / Q000523:psychology*; D005260:Female; D040261:Harm Reduction; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008875:Middle Aged; D008960:Models, Psychological; D010555:Personality Inventory / Q000706:statistics & numerical data; D011569:Psychiatric Status Rating Scales; D012649:Self Concept; D013694:Temperament