title: Clinical aspects: focusing on key unique organ-specific issues of renal transplantation.
abstract: Kidney transplantation is the treatment of choice for patients with end-stage renal disease because of improved patient survival and quality of life as compared with dialysis. Successful transplantation requires the prompt recognition and appropriate management of both the immediate posttransplant surgical and medical complications as well as subsequent issues like recurrent disease and chronic rejection that affect long-term graft survival. Guidelines for understanding and managing some of the more important early and late kidney-specific transplant problems, including urologic complications, delayed graft function, acute and chronic rejection, BK polyoma virus infection, and recurrent glomerular disease, are reviewed.
authors.affiliation: Division of Nephrology, Department of Medicine, Connie Frank Transplant Center at UCSF, San Francisco, California 04143.
authors.forename: Sindhu
authors.initials: S
authors.lastname: Chandran
authors.forename: Flavio
authors.initials: F
authors.lastname: Vincenti
mesh_terms: D005260:Female; D006084:Graft Rejection / Q000209:etiology / Q000628:therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000379:methods*; D009894:Opportunistic Infections / Q000139:chemically induced / Q000517:prevention & control; D009928:Organ Specificity; D027601:Polyomavirus Infections / Q000139:chemically induced / Q000517:prevention & control; D011183:Postoperative Complications / Q000209:etiology / Q000628:therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000517:prevention & control; D012008:Recurrence; D057049:Thrombotic Microangiopathies / Q000209:etiology / Q000628:therapy; D014517:Ureteral Obstruction / Q000209:etiology / Q000628:therapy; D014555:Urination Disorders / Q000209:etiology / Q000628:therapy
chemical_list: D007166:Immunosuppressive Agents