title: Chiari type I malformation caused by craniometaphyseal dysplasia.
abstract: Craniometaphyseal dysplasia is a rare genetic condition characterized by progressive thickening of bones in the skull and metaphyseal abnormalities in the long bones. This disorder often causes progressively symptomatic cranial nerve compression, but in rare cases foramen magnum stenosis may lead to quadriplegia. Chiari I malformation with craniometaphyseal dysplasia is extremely rare. The authors report on a 25-year-old woman with myelopathy due to Chiari I malformation along with craniometaphyseal dysplasia. There are only four previous case reports of this condition. The authors present here the fifth case report of this rare condition and summarize its characteristics.
authors.affiliation: Department of Orthopaedic Surgery, Okayama University Hospital, Okayama 700-8558, Japan.tanakam@md.okayama-u.ac.jp.
authors.forename: Masato
authors.initials: M
authors.lastname: Tanaka
authors.forename: Shinya
authors.initials: S
authors.lastname: Arataki
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Sugimoto
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Takigawa
authors.forename: Tomoko
authors.initials: T
authors.lastname: Tetsunaga
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Ozaki
mesh_terms: D000328:Adult; D001139:Arnold-Chiari Malformation / Q000175:diagnosis / Q000209:etiology*; D001848:Bone Diseases, Developmental / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D016723:Bone Remodeling / Q000235:genetics; D019465:Craniofacial Abnormalities / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D005260:Female; D006801:Humans; D015576:Hyperostosis / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D006972:Hypertelorism / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D012886:Skull / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed