title: Stromal alterations as quantitative optical biomarkers of epithelial tumor progression.
abstract: Stroma plays an important role during epithelial tumor progression. Probing stroma alteration may become an intrinsic indicator for evaluating epithelial tumor progression. In this review, we summarize our recent works on stromal alterations as quantitative optical biomarkers of epithelial tumor progression by use of nonlinear optical microscopy.
authors.affiliation: Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, 350007, China.
authors.forename: Shuangmu
authors.initials: S
authors.lastname: Zhuo
authors.forename: Jianxin
authors.initials: J
authors.lastname: Chen
mesh_terms: D015415:Biomarkers; D018450:Disease Progression; D006801:Humans; D008853:Microscopy / Q000379:methods*; D009375:Neoplasms, Glandular and Epithelial / Q000175:diagnosis* / Q000473:pathology*
chemical_list: D015415:Biomarkers
keywords: epithelial tumor progression; nonlinear optical microscopy; stroma