title: [Detection and significance of CXCL8 and IL-10 in serum and tissue of the patients' with OSAHS].
abstract: OBJECTIVE
  Detection and significance of CXCL8, IL-10 in serum and tissue of the patients' with OSHAS.
  
  
  METHODS
  All subjects take serum CXCL8 and IL-10 levels were determined by ELISA. All subjects take the same position of the soft palate tissues in the operation. CXCL8 and IL-10 in the tissue expression was measured by immune histochemistry.
  
  
  RESULTS
  (1) Serum CXCL8 levels in OSHAS is higher than that in the control group (P < 0.05). (2) Serum IL-10 levels in OSHAS is lower than that in the control group (P < 0.05). (3) Tissues CXCL8 expression was correlated with serum CXCL8 (r = 0.474, P < 0.05). (4) Tissues IL-10 expression wasn't any correlated with serum IL-10. (5) Tissues IL-10 expression was correlated with tissues CXCL8 (r = 0.482, P < 0.05).
  
  
  CONCLUSIONS
  OSAHS may be a disease associated with inflammation, and closely relate with CXCL8 and IL-10.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, 710004, China.
authors.forename: Liqiao
authors.initials: L
authors.lastname: Ge
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, 710004, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Hou
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, 710004, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Yan
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, 710004, China.
authors.forename: Quanqing
authors.initials: Q
authors.lastname: Kang
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D016753:Interleukin-10 / Q000097:blood* / Q000378:metabolism; D016209:Interleukin-8 / Q000097:blood* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D020181:Sleep Apnea, Obstructive / Q000097:blood* / Q000378:metabolism
chemical_list: C508606:CXCL8 protein, human; C508609:IL10 protein, human; D016209:Interleukin-8; D016753:Interleukin-10