title: Cytokines and chemokines in irritant contact dermatitis.
abstract: Irritant contact dermatitis is a result of activated innate immune response to various external stimuli and consists of complex interplay which involves skin barrier disruption, cellular changes, and release of proinflammatory mediators. In this review, we will focus on key cytokines and chemokines involved in the pathogenesis of irritant contact dermatitis and also contrast the differences between allergic contact dermatitis and irritant contact dermatitis.
authors.affiliation: Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland.
authors.forename: Haur Yueh
authors.initials: HY
authors.lastname: Lee
authors.affiliation: Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland.
authors.forename: Marco
authors.initials: M
authors.lastname: Stieger
authors.affiliation: Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland.
authors.forename: Nikhil
authors.initials: N
authors.lastname: Yawalkar
authors.affiliation: Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland ; Department of Dermatology, Mie University Graduate School of Medicine, Tsu, Mie 514-8507, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Kakeda
mesh_terms: D000818:Animals; D018925:Chemokines / Q000502:physiology*; D016207:Cytokines / Q000502:physiology*; D003713:Dendritic Cells / Q000502:physiology; D017453:Dermatitis, Irritant / Q000209:etiology* / Q000276:immunology; D042783:Endothelial Cells / Q000502:physiology; D005347:Fibroblasts / Q000502:physiology; D006801:Humans; D015603:Keratinocytes / Q000502:physiology; D008214:Lymphocytes / Q000502:physiology
chemical_list: D018925:Chemokines; D016207:Cytokines