title: An 85-year-old woman with Miller Fisher syndrome.
abstract: Miller Fisher's syndrome (MFS) commonly presents in the fourth and fifth decades and are rare in people over 70 years. An 85-year-old female with no significant medical history presented with upper extremity anesthesia, ptosis, and unsteady gait. The patient had a history of hypertension and diabetes mellitus. Physical examination showed bilateral total external ophthalmoplegia, areflexia, and cerebellar ataxia. Radiological and laboratory studies were unremarkable. Lumbar puncture showed albuminocytological dissociation. The combined history, physical examination, and lumbar puncture results established a presumptive diagnosis of MFS. Intravenous immunoglobulin was given for 5 days. The patient gradually improved 10 days after the onset of symptoms. Ophthalmoplegia had fully recovered after 6 months. To the best of our knowledge, this case represented the oldest patient with MFS.
authors.affiliation: Shu-hui Wang, Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Shu-Hui
authors.initials: SH
authors.lastname: Wang
authors.affiliation: Yong-bo Zhang, Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Yong-Bo
authors.initials: YB
authors.lastname: Zhang
authors.affiliation: Yan-chen Xie, Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Yan-Chen
authors.initials: YC
authors.lastname: Xie
authors.affiliation: De-xin Wang, Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: De-Xin
authors.initials: DX
authors.lastname: Wang
authors.affiliation: Ji-mei Li, Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Ji-Mei
authors.initials: JM
authors.lastname: Li
keywords: 80 and over; Aged; Miller Fisher’s syndrome; Ophthalmoplegia