title: Good functional outcome and adjacent segment disc quality 10 years after single-level anterior lumbar interbody fusion with posterior fixation.
abstract: We reviewed the records of a prospective consecutive cohort to evaluate the clinical performance of anterior lumbar interbody fusion with a titanium box cage and posterior fixation, with emphasis on long-term functional outcome. Thirty-two patients with chronic low back pain underwent anterior lumbar interbody fusion and posterior fixation. Radiological and functional results (visual analogue scale [VAS] and Oswestry score) were evaluated. Adjacent segment degeneration (ASD) was evaluated radiologically and by magnetic resonance imaging (MRI). Twenty-five patients (78%) were available for follow-up. Functional scores showed significant improvement in pain and function up to the 2-year follow-up observation. At 4 years, there was some deterioration of the clinical results. At 10-year follow-up, results remained stable compared with 4-year results. MRI showed ASD in 3/25 (12%) above and 2/10 (20%) below index level (compared with absent preoperatively). ASD could not be related to clinical outcome in this study. Anterior lumbar interbody fusion and posterior fixation is safe and effective. Initial improvement in VAS and Oswestry scores is partly lost at the 4-year follow-up. Good clinical results are maintained at 10-year follow-up and are not related to adjacent segment degeneration.
authors.affiliation: Department of Orthopedic Surgery, Sint Maartenskliniek, Nijmegen, The Netherlands.
authors.forename: Philip P
authors.initials: PP
authors.lastname: Horsting
authors.affiliation: Department of Orthopedic Surgery, Sint Maartenskliniek, Nijmegen, The Netherlands.
authors.forename: Paul W
authors.initials: PW
authors.lastname: Pavlov
authors.affiliation: Department of Neurosurgery, Leids Universitair Medisch Centrum, RC Leiden, The Netherlands.
authors.forename: Wilco C H
authors.initials: WC
authors.lastname: Jacobs
authors.affiliation: Department of Radiology, Sint Maartenskliniek, Nijmegen, The Netherlands.
authors.forename: Marina
authors.initials: M
authors.lastname: Obradov-Rajic
authors.affiliation: Department of Orthopedic Surgery, Sint Maartenskliniek, Nijmegen, The Netherlands.
authors.forename: Marinus
authors.initials: M
authors.lastname: de Kleuver
keywords: adjacent segment disease; anterior lumbar fusion; functional outcome; long-term follow-up