title: Synthesis of near-infrared quantum dots in cultured cancer cells.
abstract: Intracellular synthesis of near-infrared fluorescent silver sulfide quantum dots in HepG2 cancer cells is demonstrated. By delivering quantum dot precursors into cultured hepatoma carcinoma cells (HepG2 cells), silver sulfide quantum dots with emission efficiency qualified for in vivo imaging were successfully synthesized with the aid of endogenous glutathione in the cells.
authors.affiliation: School of Chemistry and Chemical Engineeringand ‡School of Pharmacy, Shanghai Jiao Tong University , Shanghai, 200240, China.
authors.forename: Lianjiang
authors.initials: L
authors.lastname: Tan
authors.forename: Ajun
authors.initials: A
authors.lastname: Wan
authors.forename: Huili
authors.initials: H
authors.lastname: Li
mesh_terms: D000818:Animals; D005453:Fluorescence; D056945:Hep G2 Cells; D006801:Humans; D051379:Mice; D046529:Microscopy, Electron, Transmission; D045663:Quantum Dots; D018030:Silver Compounds / Q000138:chemical synthesis*; D019265:Spectroscopy, Near-Infrared
chemical_list: D018030:Silver Compounds; C013251:silver sulfide