title: Understanding depot antipsychotics: an illustrated guide to kinetics.
abstract: Long-acting injectable (LAI) antipsychotics can have considerable advantages over oral medications for the management of patients with schizophrenia. Despite the high prevalence of treatment nonadherence with oral pharmacotherapy, LAI antipsychotics are significantly underutilized in this patient population. The availability of newer LAI antipsychotic preparations combined with a resurgent interest in the use of typical antipsychotics has rekindled awareness of the value of LAI medications. This article is intended to provide a visual understanding of the various kinetic profiles of LAI antipsychotics to facilitate initiation and greater use of these agents.
authors.affiliation: Patton State Hospital, Patton, California, USA; Mental Health Intensive Case Management, VA San Diego Healthcare System, San Diego, California, USA; Department of Psychiatry, University of California, San Diego School of Medicine, San Diego, California, USA; Department of Psychiatry, Loma Linda University, Loma Linda, California, USA.
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Meyer
mesh_terms: D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D003692:Delayed-Action Preparations; D006801:Humans
chemical_list: D014150:Antipsychotic Agents; D003692:Delayed-Action Preparations