title: Simultaneous stereoselective detection of chiral fungicides in soil by LC-MS/MS with fast sample preparation.
abstract: An enantioselective method was developed for the simultaneous detection of five chiral fungicides in soil, including fenbuconazole (1), tetraconazole (2), nuarimol (3), triticonazole (4), and simeconazole (5) by LC-MS/MS on a chiral stationary phase of cellulose tris-(3-chloro-4-methylphenylcarbamate) with a gradient elution. A new multifunctional filter was designed to simplify the QuEChERS (where QuEChERS is quick, easy, cheap, effective, rugged, and safe) method by simultaneous cleanup and filtration when the sample extracts were directly passed through it. Good linearities (R2 > 0.9980) were obtained in the range 0.005-2.5 mg/L, and the recovery rates were 77.4-103.6% with RSDs of 0.7-12.2% for intraday precision and 1.2-11.0% for interday precision. The LODs and LOQs for all enantiomers were in the range 0.1-0.2 and 0.25-0.5 μg/kg, respectively. The analysis of the incubated soil suggests that this method is reliable and practical for the stereoselective detection of chiral fungicides.
authors.affiliation: Institute of Quality Standards & Testing Technology for Agro-Products, Key Laboratory of Agro-Product Quality and Safety, Chinese Academy of Agricultural Sciences, Beijing, China; Key Laboratory of Agri-food Quality and Safety, Ministry of Agriculture, Beijing, China; College of Science, China Agricultural University, Beijing, China.
authors.forename: Tingting
authors.initials: T
authors.lastname: Chai
authors.forename: Qi
authors.initials: Q
authors.lastname: Jia
authors.forename: Shuming
authors.initials: S
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: Qiu
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D005659:Fungicides, Industrial / Q000737:chemistry* / Q000302:isolation & purification; D012989:Soil Pollutants / Q000737:chemistry* / Q000302:isolation & purification; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D013237:Stereoisomerism; D053719:Tandem Mass Spectrometry / Q000379:methods*
chemical_list: D005659:Fungicides, Industrial; D012989:Soil Pollutants
keywords: Chiral fungicides; Enantiomers; Enantioselective degradation; Soil; Stereoselective detection