title: A novel alternative for renal replacement therapy: 2-year successful colonic dialysis via a Malone antegrade continent enema stoma.
abstract: This study is a case report of home-based colonic dialysis (CD) for treating end-stage renal disease in a 20-year-old woman. She had a history of Malone antegrade continence enema (MACE) for treating neuropathic bowel at the age of 11 years. The patient refused any type of renal replacement therapy. However, she agreed to CD through the MACE stoma by changing the colonic irrigation solution to the peritoneal dialysis solution. The patient was discharged with a plasma creatinine (Cr) level of 1.7 mg/dL and blood urea nitrogen (BUN) level of 8 mg/dL. She has continued CD on a regular basis at home. The patient's serum Cr and BUN has remained in the steady low state during 24 months of follow-up (mean Cr level = 2.8 mg/dL and mean BUN level = 10.7 mg/dL).
authors.affiliation: Pediatric Urology Research Center, Pediatric Center of Excellence, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran. Electronic address: kajbafzd@sina.tums.ac.ir.
authors.forename: Abdol-Mohammad
authors.initials: AM
authors.lastname: Kajbafzadeh
authors.affiliation: Pediatric Urology Research Center, Pediatric Center of Excellence, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors.forename: Atefeh
authors.initials: A
authors.lastname: Zeinoddini
authors.affiliation: Pediatric Urology Research Center, Pediatric Center of Excellence, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Heidari
authors.affiliation: Pediatric Urology Research Center, Pediatric Center of Excellence, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors.forename: Haleh
authors.initials: H
authors.lastname: NaserHodjjati
authors.affiliation: Division of Pediatric Urology, Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Tourchi
mesh_terms: D003125:Colostomy / Q000379:methods*; D004733:Enema / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D017582:Renal Replacement Therapy / Q000379:methods*; D013997:Time Factors; D055815:Young Adult
keywords: Dialysis; End stage renal disease; Intestinal/colonic dialysis; Renal replacement therapy