title: Samarium(III)-catalyzed C(sp3)-H bond activation: synthesis of indolizines via C-C and C-N coupling between 2-alkylazaarenes and propargylic alcohols.
abstract: A new rare earth metal and samarium-catalyzed C(sp(3))-H bond activation is reported in which 2-alkylazaarenes and propargylic alcohols were converted to indolizines. This process operates under mild conditions and solvent-free conditions. A broad scope of coupling partners has been established, and a likely mechanism has also been suggested.
authors.affiliation: Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), School of Chemistry & Chemical Engineering of Guangxi Normal University , Guilin 541004, People's Republic of China.
authors.forename: Xu
authors.initials: X
authors.lastname: Wang
authors.forename: Shen-yan
authors.initials: SY
authors.lastname: Li
authors.forename: Ying-ming
authors.initials: YM
authors.lastname: Pan
authors.forename: Heng-shan
authors.initials: HS
authors.lastname: Wang
authors.forename: Hong
authors.initials: H
authors.lastname: Liang
authors.forename: Zhen-feng
authors.initials: ZF
authors.lastname: Chen
authors.forename: Xiao-huan
authors.initials: XH
authors.lastname: Qin
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001372:Aza Compounds / Q000737:chemistry*; D002384:Catalysis; D007212:Indolizines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D020005:Propanols / Q000737:chemistry*; D012493:Samarium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001372:Aza Compounds; D007212:Indolizines; D020005:Propanols; D012493:Samarium; C028255:propargyl alcohol