title: Synovial fluid CD1c+ myeloid dendritic cells – the inflammatory picture emerges.
abstract: Dendritic cells (DCs) comprise a heterogeneous group of antigen-presenting cells with many specialized functions, including essential constitutive roles in priming immune and autoimmune responses and in the maintenance of peripheral self-tolerance. At the interface of the innate and adaptive immune systems, they contribute considerably to the production of inflammatory and anti-inflammatory mediators with diverse functions. Emerging evidence suggests that the wide involvement of DCs in immunity and tolerance reflects the function of specialized DC subsets.
authors.forename: Ranjeny
authors.initials: R
authors.lastname: Thomas
mesh_terms: D018949:Antigens, CD1 / Q000276:immunology*; D018925:Chemokines / Q000276:immunology*; D003713:Dendritic Cells / Q000276:immunology*; D005260:Female; D006023:Glycoproteins / Q000276:immunology*; D006801:Humans; D008213:Lymphocyte Activation / Q000276:immunology*; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*
chemical_list: D018949:Antigens, CD1; D018925:Chemokines; D006023:Glycoproteins