title: Paracetamol vs dexketoprofen for perineal pain relief after episiotomy or perineal tear.
abstract: A randomised controlled trial was conducted to investigate efficacy of paracetamol and dexketoprofen trometamol for perineal pain relief after perineal repair. Subjects were randomly assigned to receive two doses of either 50 mg of intravenous dexketoprofen trometamol via slow i.v. infusion (Group I, n = 49) or 1,000 mg of paracetamol via intravenous infusion (Group II, n = 46). The main outcome measure was a VAS (visual analogue scale) for pain recorded at 1 h (VAS 1). A total of 82 patients were included in the final analysis (Group I, n = 41; Group II, n = 41). There was no difference among groups in terms of pain scores at the beginning (VAS 0). The pain was decreased in 70% of the patients in Group I and in 62% of the patients in Group II (p = 0.502). Both paracetamol and dexketoprofen are effective in perineal pain relief after episiotomy or perineal tear repair.
authors.affiliation: Bodrum Acıbadem Hospital , Bodrum , Mugla.
authors.forename: A
authors.initials: A
authors.lastname: Akil
authors.forename: O
authors.initials: O
authors.lastname: Api
authors.forename: Y
authors.initials: Y
authors.lastname: Bektas
authors.forename: A Onan
authors.initials: AO
authors.lastname: Yilmaz
authors.forename: S
authors.initials: S
authors.lastname: Yalti
authors.forename: O
authors.initials: O
authors.lastname: Unal
mesh_terms: D000082:Acetaminophen / Q000627:therapeutic use*; D000328:Adult; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004311:Double-Blind Method; D004841:Episiotomy / Q000009:adverse effects; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007660:Ketoprofen / Q000031:analogs & derivatives* / Q000627:therapeutic use; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D010502:Perineum / Q000293:injuries; D011247:Pregnancy; D014325:Tromethamine / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D018712:Analgesics, Non-Narcotic; D000894:Anti-Inflammatory Agents, Non-Steroidal; D014325:Tromethamine; D000082:Acetaminophen; D007660:Ketoprofen; C118296:dexketoprofen trometamol