title: MOPED enables discoveries through consistently processed proteomics data.
abstract: The Model Organism Protein Expression Database (MOPED, http://moped.proteinspire.org) is an expanding proteomics resource to enable biological and biomedical discoveries. MOPED aggregates simple, standardized and consistently processed summaries of protein expression and metadata from proteomics (mass spectrometry) experiments from human and model organisms (mouse, worm, and yeast). The latest version of MOPED adds new estimates of protein abundance and concentration as well as relative (differential) expression data. MOPED provides a new updated query interface that allows users to explore information by organism, tissue, localization, condition, experiment, or keyword. MOPED supports the Human Proteome Project's efforts to generate chromosome- and diseases-specific proteomes by providing links from proteins to chromosome and disease information as well as many complementary resources. MOPED supports a new omics metadata checklist to harmonize data integration, analysis, and use. MOPED's development is driven by the user community, which spans 90 countries and guides future development that will transform MOPED into a multiomics resource. MOPED encourages users to submit data in a simple format. They can use the metadata checklist to generate a data publication for this submission. As a result, MOPED will provide even greater insights into complex biological processes and systems and enable deeper and more comprehensive biological and biomedical discoveries.
authors.forename: Roger
authors.initials: R
authors.lastname: Higdon
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Stewart
authors.forename: Larissa
authors.initials: L
authors.lastname: Stanberry
authors.forename: Winston
authors.initials: W
authors.lastname: Haynes
authors.forename: John
authors.initials: J
authors.lastname: Choiniere
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Montague
authors.forename: Nathaniel
authors.initials: N
authors.lastname: Anderson
authors.forename: Gregory
authors.initials: G
authors.lastname: Yandl
authors.forename: Imre
authors.initials: I
authors.lastname: Janko
authors.forename: William
authors.initials: W
authors.lastname: Broomall
authors.forename: Simon
authors.initials: S
authors.lastname: Fishilevich
authors.forename: Doron
authors.initials: D
authors.lastname: Lancet
authors.forename: Natali
authors.initials: N
authors.lastname: Kolker
authors.forename: Eugene
authors.initials: E
authors.lastname: Kolker
mesh_terms: D000818:Animals; D030562:Databases, Protein; D006801:Humans; D040901:Proteomics; D014584:User-Computer Interface