title: Pain hypervigilance is associated with greater clinical pain severity and enhanced experimental pain sensitivity among adults with symptomatic knee osteoarthritis.
abstract: BACKGROUND
  Pain hypervigilance is an important aspect of the fear-avoidance model of pain that may help explain individual differences in pain sensitivity among persons with knee osteoarthritis (OA).
  
  
  OBJECTIVE
  The purpose of this study was to examine the contribution of pain hypervigilance to clinical pain severity and experimental pain sensitivity in persons with symptomatic knee OA.
  
  
  METHODS
  We analyzed cross-sectional data from 168 adults with symptomatic knee OA. Quantitative sensory testing was used to measure sensitivity to heat pain, pressure pain, and cold pain, as well as temporal summation of heat pain, a marker of central sensitization.
  
  
  RESULTS
  Pain hypervigilance was associated with greater clinical pain severity, as well as greater pressure pain. Pain hypervigilance was also a significant predictor of temporal summation of heat pain.
  
  
  CONCLUSIONS
  Pain hypervigilance may be an important contributor to pain reports and experimental pain sensitivity among persons with knee OA.
authors.affiliation: College of Arts and Sciences, Department of Psychology, University of Alabama at Birmingham, 1825 University Blvd., Shelby 177E, Birmingham, AL, 35294, USA, mherbert@uab.edu.
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Herbert
authors.forename: Burel R
authors.initials: BR
authors.lastname: Goodin
authors.forename: Samuel T
authors.initials: ST
authors.lastname: Pero
authors.forename: Jessica K
authors.initials: JK
authors.lastname: Schmidt
authors.forename: Adriana
authors.initials: A
authors.lastname: Sotolongo
authors.forename: Hailey W
authors.initials: HW
authors.lastname: Bulls
authors.forename: Toni L
authors.initials: TL
authors.lastname: Glover
authors.forename: Christopher D
authors.initials: CD
authors.lastname: King
authors.forename: Kimberly T
authors.initials: KT
authors.lastname: Sibille
authors.forename: Yenisel
authors.initials: Y
authors.lastname: Cruz-Almeida
authors.forename: Roland
authors.initials: R
authors.lastname: Staud
authors.forename: Barri J
authors.initials: BJ
authors.lastname: Fessler
authors.forename: Laurence A
authors.initials: LA
authors.lastname: Bradley
authors.forename: Roger B
authors.initials: RB
authors.lastname: Fillingim
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000150:complications / Q000523:psychology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000150:complications / Q000523:psychology*; D010146:Pain / Q000150:complications / Q000523:psychology*; D010147:Pain Measurement; D017288:Pain Threshold / Q000523:psychology*; D012720:Severity of Illness Index