title: Allopurinol induced erythroderma.
abstract: Allopurinol, a widely prescribed urate lowering agent is responsible for various adverse drug reactions, including erythroderma. A 45-year-old male patient was admitted with the complaints of fever, redness and scaling all over the body after 3-4 weeks of allopurinol treatment for asymptomatic hyperuricemia. Elevated liver enzymes were detected in his blood analysis. Skin biopsy was consistent with drug induced erythroderma. Allopurinol was stopped and steroids were started. Patient improved over a period of 2 weeks.
authors.affiliation: Departments of Dermatology and Dermatology and Venereology, Rama Medical College, Hospital and Research Centre, Mandhana, Kanpur, Uttar Pradesh, India.
authors.forename: Geeta
authors.initials: G
authors.lastname: Sharma
authors.affiliation: Departments of Dermatology and Dermatology and Venereology, Rama Medical College, Hospital and Research Centre, Mandhana, Kanpur, Uttar Pradesh, India.
authors.forename: Dinesh Chandra
authors.initials: DC
authors.lastname: Govil
mesh_terms: D000493:Allopurinol / Q000009:adverse effects*; D003873:Dermatitis, Exfoliative / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014527:Uric Acid / Q000097:blood
chemical_list: D014527:Uric Acid; D000493:Allopurinol
keywords: Allopurinol; erythroderma; hyperuricemia