title: Prophylactic antibiotics used in patients of hepatobiliary surgery.
abstract: OBJECTIVE
  To clarify the use of antibiotics in our hospital and to guide the prophylactic use in future hepatobiliary surgical procedures.
  
  
  METHODS
  A retrospective review of patients who underwent hepatobiliary surgery from January 2011 to June 2011 was included. Data were collected, and surgical site infection (SSI) was defined by the criteria of Center for Disease Control and Prevention. Patients were prescribed antibiotics for the clinical diagnosis of hepatobiliary system diseases.
  
  
  RESULTS
  1564 patients were identified, in which 784 patients (50.13%) did not receive preoperative antibiotic prophylaxis. Of these 355 patients with 784 surgical sites received either preoperative or both preoperative and postoperative antibiotic prophylaxis. The SSI rate of the patients who received prophylaxis alone (2.56%, 20 of 780 sites) was not statistically higher than that of the patients who have not received prophylaxis (2.68%, 21 of 784 sites), and the two groups were not statistically correlated (P=0.77).
  
  
  CONCLUSIONS
  The number of the patients who developed SSI was relatively low, and no reduction in the SSI rate was observed among the patients who have received antibiotic prophylaxis.
authors.affiliation: Jianjun Ren, Department of General Surgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot-010059, P. R. China.
authors.forename: Jianjun
authors.initials: J
authors.lastname: Ren
authors.affiliation: Lidao Bao, Department of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot-010059, P. R. China.
authors.forename: Lidao
authors.initials: L
authors.lastname: Bao
authors.affiliation: Jianxiang Niu, Department of General Surgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot-010059, P. R. China.
authors.forename: Jianxiang
authors.initials: J
authors.lastname: Niu
authors.affiliation: Yi Wang, Department of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot-010059, P. R. China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Xianhua Ren, Affiliated Hospital of Inner Mongolia Medical University, Hohhot-010059, P. R. China.
authors.forename: Xianhua
authors.initials: X
authors.lastname: Ren
keywords: Antibiotics; Hepatobiliary; Prophylactic; Surgical site infection