title: Remineralization of Root Caries Monitored Using Cross-Polarization Optical Coherence Tomography.
abstract: Previous studies have demonstrated that polarization sensitive optical coherence tomography (PS-OCT) can be used to image caries lesions in dentin, measure nondestructively the severity of dentin demineralization, and determine the efficacy of intervention with anticaries agents including fluoride and lasers. However, those studies were limited to artificial lesions on dentin and roots surfaces. The objective of this study is to determine if a cross polarization OCT system (CP-OCT) can be used to nondestructively measure a reduction in the reflectivity of natural root caries lesions after exposure to a remineralization solution. CP-OCT images of 11 teeth with existing root lesions were acquired before and after exposure to a remineralizing solution for 20 days. The integrated reflectivity was calculated after integrating to a fixed depth of 200-µm. There was a significant decrease in the integrated reflectivity after exposure to the remineralizing solution.
authors.affiliation: Department of Preventative and Restorative Dental Sciences, University of California, San Francisco School of Dentistry, CA 94143-0758.
authors.forename: Cynthia L
authors.initials: CL
authors.lastname: Darling
authors.affiliation: Department of Preventative and Restorative Dental Sciences, University of California, San Francisco School of Dentistry, CA 94143-0758.
authors.forename: Michal
authors.initials: M
authors.lastname: Staninec
authors.affiliation: Department of Preventative and Restorative Dental Sciences, University of California, San Francisco School of Dentistry, CA 94143-0758.
authors.forename: Kenneth H
authors.initials: KH
authors.lastname: Chan
authors.affiliation: Department of Preventative and Restorative Dental Sciences, University of California, San Francisco School of Dentistry, CA 94143-0758.
authors.forename: Hobin
authors.initials: H
authors.lastname: Kang
authors.affiliation: Department of Preventative and Restorative Dental Sciences, University of California, San Francisco School of Dentistry, CA 94143-0758.
authors.forename: Daniel
authors.initials: D
authors.lastname: Fried
keywords: dental hard tissue; dentin; optical coherence tomography; polarization; remineralization; root caries