title: Long-chain omega 3 fatty acids: molecular bases of potential antioxidant actions.
abstract: Several lines of investigation are being developed to assess the impact of polyunsaturated fatty acids, namely those of the omega 3 series, intake on oxidative stress. Keeping in mind that there might be a dose-response relation, in vivo and in vitro data strongly suggest that omega 3 fatty acids might act as anti- rather than pro-oxidant in several cells such as vascular cells, hence diminishing inflammation, oxidative stress, and, in turn, the risk of atherosclerosis and degenerative disorders such as cardiovascular disease.
authors.affiliation: Laboratory of Functional Foods, Madrid Institute for Advanced Studies (IMDEA)-Food, CEI UAM+CSIC, Madrid, Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: Giordano
authors.affiliation: Laboratory of Functional Foods, Madrid Institute for Advanced Studies (IMDEA)-Food, CEI UAM+CSIC, Madrid, Spain. Electronic address: francesco.visioli@imdea.org.
authors.forename: Francesco
authors.initials: F
authors.lastname: Visioli
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D050197:Atherosclerosis / Q000378:metabolism* / Q000473:pathology; D015525:Fatty Acids, Omega-3 / Q000378:metabolism*; D006801:Humans; D007249:Inflammation / Q000378:metabolism / Q000473:pathology; D018384:Oxidative Stress
chemical_list: D000975:Antioxidants; D015525:Fatty Acids, Omega-3
keywords: Antioxidants; Cardiovascular disease; Free radicals; Polyunsaturated fatty acids