title: Platelet-rich fibrin in the treatment of localized gingival recessions: a split-mouth randomized clinical trial.
abstract: OBJECTIVE
  The aim of this study is to evaluate the clinical efficacy of platelet-rich fibrin (PRF) in combination with coronally advanced flap (CAF) in the treatment of localized gingival recessions.
  
  
  METHODS
  Twenty-two patients with localized gingival recession defects (Miller I, II) participated in this split-mouth trial. Forty-four defects received either CAF + PRF (test) or CAF with subepithelial connective tissue graft (SCTG) (control). Gingival recession depth (RD), gingival recession width (RW), keratinized tissue width (KTW), recession area (RA), probing depth (PD), clinical attachment level (CAL) and gingival thickness (GT) were evaluated at baseline and 6 months. RD, RW, RA and KTW were calculated on standardized photographs with a computer image analysis program.
  
  
  RESULTS
  Percentage of root coverage in test group was 92.7 % and in control group was 94.2 % (p > 0.05). Percentage of complete root coverage of the test and control groups was 72.7 and 77.3 %, respectively (p > 0.05). KTW and GT were increased in both groups from baseline to 6 months (p < 0.001), but there was no statistically significant difference between treatment groups (p > 0.05).
  
  
  CONCLUSIONS
  Within the limits of the present study, it can be concluded that localized gingival recessions could be successfully treated with CAF + PRF as well as CAF + SCTG. The digital measuring method provided high accuracy and precision in the evaluation of treatment outcomes after both surgical procedures.
  
  
  CONCLUSIONS
  PRF might be suggested as an alternative to SCTG for the treatment of localized gingival recessions.
authors.affiliation: Department of Periodontology, School of Dentistry, Ege University, 35100, Bornova, İzmir, Turkey, gulnihal_karasu@hotmail.com.
authors.forename: Gülnihal
authors.initials: G
authors.lastname: Eren
authors.forename: Gül
authors.initials: G
authors.lastname: Atilla
mesh_terms: D001792:Blood Platelets / Q000502:physiology*; D005337:Fibrin / Q000502:physiology*; D005889:Gingival Recession / Q000628:therapy*; D006801:Humans
chemical_list: D005337:Fibrin