title: Langerhans cell histocytosis of the mandible in a pediatric patient.
abstract: Langerhans cell histiocytosis (LCH) is a rare, proliferative disorder in which the accumulation of pathologic Langerhans cells leads to local tissue infiltration and destruction. In this article, a review of LCH is presented and a case of a single LCH lesion affecting the mandible of healthy infant is discussed. The history, radiological appearance, histopathology and treatment options are discussed.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Boston University, Boston Medical Center, Boston, Mass., USA. alshadwi@bu.edu.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Alshadwi
authors.affiliation: Department of Oral and Maxillofacial Surgery, Boston University, Boston Medical Center, Boston, Mass., USA.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Nadershah
authors.affiliation: College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Saleh
authors.initials: S
authors.lastname: AlBazie
mesh_terms: D003937:Diagnosis, Differential; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007223:Infant; D008297:Male; D008336:Mandibular Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery