title: CapMan: independent investigation of capacity and manipulation with a new working memory paradigm.
abstract: In a new working memory paradigm, CapMan, we independently investigated brain activity associated with capacity and manipulation of information. The investigation of Capacity, resulted in activation of the fronto-parietal network of regions that overlapped with areas usually found to be active in working memory tasks. The investigation of Manipulation revealed a more dorsal network of areas that also overlapped with areas usually found to be active in working memory tasks, but that did not overlap with the areas associated with Capacity. The CapMan paradigm thus appears to be able to separate the processes associated with capacity and manipulation increases and promises to be a valuable addition to the tools available for the study of working memory.
authors.affiliation: Neuropsychology & Neuroscience Laboratory, Kessler Foundation Research Center, 300 Executive Drive, Suite 70, West Orange, NJ, 07052, USA.
authors.forename: Ekaterina
authors.initials: E
authors.lastname: Dobryakova
authors.forename: Adam
authors.initials: A
authors.lastname: Staffaroni
authors.forename: John
authors.initials: J
authors.lastname: DeLuca
authors.forename: James F
authors.initials: JF
authors.lastname: Sumowski
authors.forename: Nancy
authors.initials: N
authors.lastname: Chiaravalloti
authors.forename: Glenn R
authors.initials: GR
authors.lastname: Wylie
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D002560:Cerebrovascular Circulation / Q000502:physiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008570:Memory, Short-Term / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology; D009483:Neuropsychological Tests; D010100:Oxygen / Q000097:blood
chemical_list: D010100:Oxygen