title: Prevalence of major cardiovascular risk factors and adverse risk profiles among three ethnic groups in the Xinjiang Uygur Autonomous Region, China.
abstract: BACKGROUND
  Prevalence of cardiovascular disease (CVD) risk factors have been scarcely studied in Xinjiang, a multi-ethnic region.
  
  
  METHODS
  Multi-ethnic, cross-sectional cardiovascular risk survey study in Xinjiang, including individuals of Uygur (n = 4695), Han (n = 3717) and Kazakh (n = 3196) ethnicities, aged 35-74 years. Analyses involved 11,608 participants with complete data enrolled between October 2007 and March 2010.
  
  
  RESULTS
  There were differences in age-standardized prevalence of CVD risk factors between the three groups (all P < 0.001). Hypertension, obesity and smoking rates were higher among Kazakh (54.6%, 24.5%, and 35.8%, respectively). Dyslipidemia prevalence was higher among Uygur (54.3%), and diabetes prevalence was higher among Hans (7.1%). Age-standardized prevalence of adverse CVD risk profiles was different across different ethnicities. Compared with the Han participants, the Uygur and Kazakh had more CVD risk factors (P < 0.001). Compared with the Han participants, the adjusted odds ratios of 1, 2, and ≥3 risk factors profiles for Kazakh and Uygur participants were higher (all P < 0.001).
  
  
  CONCLUSIONS
  The present study showed the pervasive burden of CVD risk factors in all participant groups in the Xinjiang region. Three major ethnic groups living in Xinjiang had striking differences in the prevalence of major CVD risk factors and adverse risk profiles. Ethnic-specific strategies should be developed to prevent CVD in different ethnic groups, as well as to develop strategies to prevent future development of adverse CVD risk factors at a younger age.
authors.forename: Jing
authors.initials: J
authors.lastname: Tao
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, P,R, China. myt-xj@163.com.
authors.forename: Yi-tong
authors.initials: YT
authors.lastname: Ma
authors.forename: Yang
authors.initials: Y
authors.lastname: Xiang
authors.forename: Xiang
authors.initials: X
authors.lastname: Xie
authors.forename: Yi-ning
authors.initials: YN
authors.lastname: Yang
authors.forename: Xiao-mei
authors.initials: XM
authors.lastname: Li
authors.forename: Zhen-Yan
authors.initials: ZY
authors.lastname: Fu
authors.forename: Xiang
authors.initials: X
authors.lastname: Ma
authors.forename: Fen
authors.initials: F
authors.lastname: Liu
authors.forename: Bang-dang
authors.initials: BD
authors.lastname: Chen
authors.forename: Zi-xiang
authors.initials: ZX
authors.lastname: Yu
authors.forename: You
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000453:epidemiology* / Q000208:ethnology; D050171:Dyslipidemias / Q000453:epidemiology* / Q000208:ethnology; D005006:Ethnicity; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology* / Q000208:ethnology; D016017:Odds Ratio; D015995:Prevalence; D012307:Risk Factors; D012907:Smoking