title: Recent syntheses of 1,2,3,4-tetrahydroquinolines, 2,3-dihydro-4(1H)-quinolinones and 4(1H)-quinolinones using domino reactions.
abstract: A review of the recent literature is given focusing on synthetic approaches to 1,2,3,4-tetrahydroquinolines, 2,3-dihydro-4(1H)-quinolinones and 4(1H)-quinolinones using domino reactions. These syntheses involve: (1) reduction or oxidation followed by cyclization; (2) SNAr-terminated sequences; (3) acid-catalyzed ring closures or rearrangements; (4) high temperature cyclizations and (5) metal-promoted processes as well as several less thoroughly studied reactions. Each domino method is presented with a brief discussion of mechanism, scope, yields, simplicity and potential utility.
authors.forename: Baskar
authors.initials: B
authors.lastname: Nammalwar
authors.affiliation: Department of Chemistry, Oklahoma State University, Stillwater, OK 74078-3071, USA. rab@okstate.edu.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Bunce
mesh_terms: D020650:Combinatorial Chemistry Techniques; D011804:Quinolines / Q000138:chemical synthesis*; D015363:Quinolones / Q000138:chemical synthesis*
chemical_list: D011804:Quinolines; D015363:Quinolones; C542964:1,2,3,4-tetrahydroquinoline