title: A copper-mediated tandem reaction through isocyanide insertion into N-H bonds: efficient access to unsymmetrical tetrasubstituted ureas.
abstract: A copper-mediated multi-component reaction was developed through isocyanide insertion into N-H bonds of less active secondary arylamines. This approach leads to an efficient synthesis of unsymmetrical tetrasubstituted ureas in one pot.
authors.affiliation: Department of Chemistry, Shanghai University, Shanghai 200444, P. R. China. xubin@shu.edu.cn.
authors.forename: Xiaomei
authors.initials: X
authors.lastname: Huang
authors.forename: Shuguang
authors.initials: S
authors.lastname: Xu
authors.forename: Qitao
authors.initials: Q
authors.lastname: Tan
authors.forename: Mingchun
authors.initials: M
authors.lastname: Gao
authors.forename: Minjie
authors.initials: M
authors.lastname: Li
authors.forename: Bin
authors.initials: B
authors.lastname: Xu