title: Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise.
abstract: BACKGROUND
  Although several tools to evaluate the credibility of health care guidelines exist, guidance on practical steps for developing guidelines is lacking. We systematically compiled a comprehensive checklist of items linked to relevant resources and tools that guideline developers could consider, without the expectation that every guideline would address each item.
  
  
  METHODS
  We searched data sources, including manuals of international guideline developers, literature on guidelines for guidelines (with a focus on methodology reports from international and national agencies, and professional societies) and recent articles providing systematic guidance. We reviewed these sources in duplicate, extracted items for the checklist using a sensitive approach and developed overarching topics relevant to guidelines. In an iterative process, we reviewed items for duplication and omissions and involved experts in guideline development for revisions and suggestions for items to be added.
  
  
  RESULTS
  We developed a checklist with 18 topics and 146 items and a webpage to facilitate its use by guideline developers. The topics and included items cover all stages of the guideline enterprise, from the planning and formulation of guidelines, to their implementation and evaluation. The final checklist includes links to training materials as well as resources with suggested methodology for applying the items.
  
  
  CONCLUSIONS
  The checklist will serve as a resource for guideline developers. Consideration of items on the checklist will support the development, implementation and evaluation of guidelines. We will use crowdsourcing to revise the checklist and keep it up to date.
authors.forename: Holger J
authors.initials: HJ
authors.lastname: Schünemann
authors.forename: Wojtek
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authors.lastname: Wiercioch
authors.forename: Itziar
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authors.lastname: Etxeandia
authors.forename: Maicon
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authors.lastname: Falavigna
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authors.lastname: Santesso
authors.forename: Reem
authors.initials: R
authors.lastname: Mustafa
authors.forename: Matthew
authors.initials: M
authors.lastname: Ventresca
authors.forename: Romina
authors.initials: R
authors.lastname: Brignardello-Petersen
authors.forename: Kaja-Triin
authors.initials: KT
authors.lastname: Laisaar
authors.forename: Sérgio
authors.initials: S
authors.lastname: Kowalski
authors.forename: Tejan
authors.initials: T
authors.lastname: Baldeh
authors.forename: Yuan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Ulla
authors.initials: U
authors.lastname: Raid
authors.forename: Ignacio
authors.initials: I
authors.lastname: Neumann
authors.forename: Susan L
authors.initials: SL
authors.lastname: Norris
authors.forename: Judith
authors.initials: J
authors.lastname: Thornton
authors.forename: Robin
authors.initials: R
authors.lastname: Harbour
authors.forename: Shaun
authors.initials: S
authors.lastname: Treweek
authors.forename: Gordon
authors.initials: G
authors.lastname: Guyatt
authors.forename: Pablo
authors.initials: P
authors.lastname: Alonso-Coello
authors.forename: Marge
authors.initials: M
authors.lastname: Reinap
authors.forename: Jan
authors.initials: J
authors.lastname: Brozek
authors.forename: Andrew
authors.initials: A
authors.lastname: Oxman
authors.forename: Elie A
authors.initials: EA
authors.lastname: Akl
mesh_terms: D057189:Checklist; D003625:Data Collection / Q000592:standards; D019317:Evidence-Based Medicine / Q000379:methods*; D006801:Humans; D017410:Practice Guidelines as Topic / Q000592:standards*; D013223:Statistics as Topic / Q000592:standards