title: DABO Boronates: Stable Heterocyclic Boronic Acid Complexes for Use in Suzuki-Miyaura Cross-Coupling Reactions.
abstract: Diethanolamine complexed heterocyclic boronic acids (DABO boronates) are air-stable reagents that can be used directly in Suzuki-Miyaura reactions in the presence of water or a protic co-solvent. Interestingly, heterocyclic DABO boronates can be stored for extended periods of time at room temperature with no noticeable degradation, unlike their boronic acid counterparts. Heterocyclic DABO boronates constitute an operationally simple and efficient alternative to other boronic acid derivatives as coupling partners in palladium catalyzed cross-coupling reactions under standard Suzuki-Miyaura conditions.
authors.affiliation: 1102 NSII, Department of Chemistry, University of California, Irvine. Irvine, CA 92697-2025.
authors.forename: Maureen K
authors.initials: MK
authors.lastname: Reilly
authors.affiliation: 1102 NSII, Department of Chemistry, University of California, Irvine. Irvine, CA 92697-2025.
authors.forename: Scott D
authors.initials: SD
authors.lastname: Rychnovsky
keywords: Suzuki-Miyaura reaction; aryl boronate; cross-coupling; heterocyclic boronate; palladium catalysis