title: Photo-crosslinkable PEG-based microribbons for forming 3D macroporous scaffolds with decoupled niche properties.
abstract: PEG-based microribbons are designed and fabricated as building blocks for constructing a 3D cell niche with independently tunable biochemical, mechanical, and topographical cues. This platform supports direct cell encapsulation, allows spatial patterning of biochemical cues, and may provide a valuable tool for facilitating the analyses of how interactive niche signaling regulates cell fate in three dimensions.
authors.affiliation: Department of Orthopaedic Surgery, Stanford University, Stanford, CA, 94305, USA.
authors.forename: Li-Hsin
authors.initials: LH
authors.lastname: Han
authors.forename: Xinming
authors.initials: X
authors.lastname: Tong
authors.forename: Fan
authors.initials: F
authors.lastname: Yang
mesh_terms: D000273:Adipose Tissue / Q000166:cytology / Q000502:physiology; D001672:Biocompatible Materials / Q000737:chemistry*; D002465:Cell Movement / Q000502:physiology; D049109:Cell Proliferation; D003553:Cystine / Q000737:chemistry; D004548:Elasticity; D006801:Humans; D020100:Hydrogels / Q000737:chemistry*; D018613:Microscopy, Confocal; D055616:Microtechnology; D010455:Peptides / Q000378:metabolism; D011092:Polyethylene Glycols / Q000737:chemistry*; D016062:Porosity; D015398:Signal Transduction; D017154:Stromal Cells / Q000166:cytology / Q000502:physiology; D013499:Surface Properties; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D020100:Hydrogels; D010455:Peptides; D011092:Polyethylene Glycols; D003553:Cystine
keywords: biomedical applications; microribbons; scaffolds; tissue engineering