title: Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids.
abstract: A facile approach has been developed to prepare ultra-small hybrid silica spheres with a diameter of ∼10 nm, which show highly enhanced penetration ability in 3D glioma spheroids compared to conventional mesoporous silica nanoparticles.
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia. c.yu@uq.edu.au.
authors.forename: Meihua
authors.initials: M
authors.lastname: Yu
authors.forename: Surajit
authors.initials: S
authors.lastname: Karmakar
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
authors.forename: Hongwei
authors.initials: H
authors.lastname: Zhang
authors.forename: Yannan
authors.initials: Y
authors.lastname: Yang
authors.forename: Peter
authors.initials: P
authors.lastname: Thorn
authors.forename: Chengzhong
authors.initials: C
authors.lastname: Yu
mesh_terms: D001921:Brain / Q000166:cytology / Q000378:metabolism; D001932:Brain Neoplasms / Q000175:diagnosis*; D005910:Glioma / Q000175:diagnosis* / Q000378:metabolism; D006801:Humans; D053758:Nanoparticles / Q000032:analysis / Q000378:metabolism*; D010316:Particle Size; D010539:Permeability; D016062:Porosity; D012822:Silicon Dioxide / Q000032:analysis / Q000378:metabolism*; D018874:Spheroids, Cellular / Q000378:metabolism*; D014407:Tumor Cells, Cultured
chemical_list: D012822:Silicon Dioxide