title: [Design and implementation of the ELSA-Brasil biobank: a prospective study in a Brazilian population].
abstract: The Brazilian Longitudinal Study for Adult Health (ELSA-Brasil) is a multicenter prospective cohort of civil servants designed to assess the determinants of chronic diseases, especially cardiovascular diseases and type 2 diabetes. The present article describes the main design and implementation points of the ELSA-Brasil biobank project. Economic, political, logistical and technological aspects of this study are characterized. Additionally, it discusses the final biorepository protocol and the facilities implemented to achieve this objective. The design and implementation process of the ELSA-Brasil biobank took three years to be performed. Both the central and local biobanks were built according to the best biorepository techniques, using different technological solutions for the distinct needs expected in this study.
authors.forename: Alexandre C
authors.initials: AC
authors.lastname: Pereira
authors.forename: Isabela M
authors.initials: IM
authors.lastname: Bensenor
authors.forename: Ligia M
authors.initials: LM
authors.lastname: Fedeli
authors.forename: Cristina
authors.initials: C
authors.lastname: Castilhos
authors.forename: Pedro G
authors.initials: PG
authors.lastname: Vidigal
authors.forename: Viviane
authors.initials: V
authors.lastname: Maniero
authors.forename: Claudia M
authors.initials: CM
authors.lastname: Leite
authors.forename: Robercia A
authors.initials: RA
authors.lastname: Pimentel
authors.forename: Bruce B
authors.initials: BB
authors.lastname: Duncan
authors.forename: Jose Geraldo
authors.initials: JG
authors.lastname: Mill
authors.forename: Paulo A
authors.initials: PA
authors.lastname: Lotufo
mesh_terms: D000328:Adult; D018070:Biological Specimen Banks / Q000458:organization & administration* / Q000592:standards; D001938:Brazil; D002318:Cardiovascular Diseases / Q000175:diagnosis*; D002908:Chronic Disease; D003920:Diabetes Mellitus / Q000175:diagnosis*; D015340:Epidemiologic Research Design; D006801:Humans; D015337:Multicenter Studies as Topic; D011446:Prospective Studies