title: [Study of salivary biomarkers for oral squamous cell carcinoma in patients with type-2 diabetes].
abstract: According to the latest epidemiological data the occurrence of oral squamous cell carcinoma has increased recently in the last 4 decades. In spite of the great emphasis and effort in the field of prevention, novel medication therapy, our knowledge has to be enlarged in the development of this serious disease. Recent epidemiological studies and animal experiments have shown that there is a relationship between type-2 diabetes and oral squamous cell carcinoma. Our goal was to screen human saliva samples for possible biomarkers for oral malignancies in diabetic patients.
authors.affiliation: Pécsi Tudományegyetem, Klinikai Központ, Fogászati es Szájsebészeti Klinika, Maxillofaciális Részleg.
authors.forename: Veronika Agnes
authors.initials: VA
authors.lastname: Jancsik
authors.affiliation: Pécsi Tudományegyetem, Klinikai Központ, Fogászati es Szájsebészeti Klinika, Maxillofaciális Részleg.
authors.forename: László
authors.initials: L
authors.lastname: Márk
authors.affiliation: Pécsi Tudományegyetem, Klinikai Központ, Fogászati es Szájsebészeti Klinika, Maxillofaciális Részleg.
authors.forename: Gábor
authors.initials: G
authors.lastname: Gelencsér
authors.affiliation: Pécsi Tudományegyetem, Klinikai Központ, Fogászati es Szájsebészeti Klinika, Maxillofaciális Részleg.
authors.forename: Lajos
authors.initials: L
authors.lastname: Olasz
mesh_terms: D000328:Adult; D000368:Aged; D017306:Annexin A2 / Q000378:metabolism; D017302:Annexins / Q000378:metabolism*; D014408:Biomarkers, Tumor / Q000378:metabolism*; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000150:complications / Q000378:metabolism*; D054464:Peroxiredoxins / Q000378:metabolism*; D011494:Protein Kinases / Q000378:metabolism*; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D012463:Saliva / Q000378:metabolism*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: C472822:ANXA2 protein, human; D017306:Annexin A2; D017302:Annexins; D014408:Biomarkers, Tumor; D054464:Peroxiredoxins; D011494:Protein Kinases; D011505:Protein-Tyrosine Kinases