title: Determinants of systolic blood pressure response during exercise in overweight subjects.
abstract: OBJECTIVE
  Higher systolic exercise blood pressure (BP) is associated with increased cardiovascular risk in hypertension. We aimed at identifying covariates of systolic exercise BP in overweight subjects.
  
  
  METHODS
  77 subjects with body mass index (BMI) > 27 kg/m(2) and without known heart disease were tested. BP was measured by sphygmomanometry before and at all exercise stages during maximal exercise capacity testing on a treadmill. High peak systolic exercise BP was defined as ≥ 200 mmHg.
  
  
  RESULTS
  The study population was 48 ± 10 years and included 60% women and 42% with known hypertension. Average BMI was 32.6 ± 4.8 kg/m(2) and clinic BP 132/82 ± 17/8 mmHg. High systolic exercise BP was found in 32%. Subjects with high systolic exercise BP had higher systolic clinic and 24-h ambulatory BP (ABP), as well as lower peak oxygen uptake, compared with subjects with normal systolic exercise BP (all p < 0.05). In multiple regression analysis known hypertension (β = 0.33), higher systolic ABP (β = 0.22) and high-density lipoprotein (HDL)-cholesterol level (β = 0.23, all p < 0.05) predicted higher systolic exercise BP independent of sex and peak oxygen uptake (multiple R(2) = 0.32, p < 0.001).
  
  
  CONCLUSIONS
  Among overweight subjects, known hypertension, higher systolic ABP and HDL-cholesterol level were the most important factors predicting higher systolic exercise BP.
authors.affiliation: Department of Clinical Science, University of Bergen , Bergen , Norway.
authors.forename: Jon A
authors.initials: JA
authors.lastname: Bratberg
authors.forename: Efraim
authors.initials: E
authors.lastname: Bulut
authors.forename: Ashild E
authors.initials: AE
authors.lastname: Rieck
authors.forename: Mai Tone
authors.initials: MT
authors.lastname: Lønnebakken
authors.forename: Trude
authors.initials: T
authors.lastname: Hetland
authors.forename: Eva
authors.initials: E
authors.lastname: Gerdts
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D050177:Overweight / Q000503:physiopathology*; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013599:Systole
keywords: Ambulatory blood pressure; exercise blood pressure; hypertension; obesity; overweight