title: Development: getting into the groove, or evolving off the rails?
abstract: Canalization, the robust buffering against fluctuations, is often regarded as an essential feature of development. A new study identifies a genetic circuit dedicated to canalization in Drosophila melanogaster and shows striking variability in its use in different fly species.
authors.affiliation: Institute for Developmental Biology, University of Cologne, Biocenter, Zülpicher Straße 47b, 50674 Köln, Germany. Electronic address: kristen.panfilio@alum.swarthmore.edu.
authors.forename: Kristen A
authors.initials: KA
authors.lastname: Panfilio
authors.affiliation: Institute for Developmental Biology, University of Cologne, Biocenter, Zülpicher Straße 47b, 50674 Köln, Germany. Electronic address: siegfried.roth@uni-koeln.de.
authors.forename: Siegfried
authors.initials: S
authors.lastname: Roth
mesh_terms: D000818:Animals; D019521:Body Patterning / Q000235:genetics*; D029721:Drosophila Proteins / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics*; D053263:Gene Regulatory Networks; D018398:Homeodomain Proteins / Q000235:genetics*; D008565:Membrane Proteins / Q000235:genetics*; D012097:Repressor Proteins / Q000235:genetics*
chemical_list: D029721:Drosophila Proteins; D018398:Homeodomain Proteins; D008565:Membrane Proteins; D012097:Repressor Proteins; C085607:Zen protein, Drosophila; C415644:cv-2 protein, Drosophila; C464573:egr protein, Drosophila