title: [Human milk for neonatal pain relief during ophthalmoscopy].
abstract: Ophthalmoscopy performed for the early diagnosis of retinopathy of prematurity (ROP) is painful for preterm infants, thus necessitating interventions for minimizing pain. The present study aimed to establish the effectiveness of human milk, compared with sucrose, for pain relief in premature infants subjected to ophthalmoscopy for the early diagnosis of ROP. This investigation was a pilot, quasi-experimental study conducted with 14 premature infants admitted to the neonatal intensive care unit (NICU) of a university hospital. Comparison between the groups did not yield a statistically significant difference relative to the crying time, salivary cortisol, or heart rate (HR). Human milk appears to be as effective as sucrose in relieving acute pain associated with ophthalmoscopy. The study's limitations included its small sample size and lack of randomization. Experimental investigations with greater sample power should be performed to reinforce the evidence found in the present study.
authors.affiliation: University of Brasilia, Brasília, Brazil.
authors.forename: Laiane Medeiros
authors.initials: LM
authors.lastname: Ribeiro
authors.affiliation: University of Goiás, Goiania, Brazil.
authors.forename: Thaíla Corrêa
authors.initials: TC
authors.lastname: Castral
authors.affiliation: Graduate Program in Public Health Nursing, University of São Paulo, Ribeirão Preto, Brazil.
authors.forename: Liciane Langona
authors.initials: LL
authors.lastname: Montanholi
authors.affiliation: Graduate Program in Public Health Nursing, University of São Paulo, Ribeirão Preto, Brazil.
authors.forename: Mariana Firmino
authors.initials: MF
authors.lastname: Daré
authors.affiliation: University of São Paulo, Ribeirão Preto, Brazil.
authors.forename: Aline Carolina de Araújo
authors.initials: AC
authors.lastname: Silva
authors.affiliation: School of Medicine, University of São Paulo, Ribeirão Preto, Brazil.
authors.forename: Sonir Roberto Rauber
authors.initials: SR
authors.lastname: Antonini
authors.affiliation: School of Nursing, University of São Paulo, Ribeirão Preto, Brazil.
authors.forename: Carmen Gracinda Silvan
authors.initials: CG
authors.lastname: Scochi
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008895:Milk, Human; D009887:Ophthalmoscopy / Q000009:adverse effects; D010146:Pain / Q000209:etiology; D059408:Pain Management / Q000379:methods*; D010865:Pilot Projects; D013395:Sucrose / Q000627:therapeutic use
chemical_list: D013395:Sucrose