title: Contribution of the cashew gum (Anacardium occidentale L.) for development of layer-by-layer films with potential application in nanobiomedical devices.
abstract: The search for bioactive molecules to be employed as recognition elements in biosensors has stimulated researchers to pore over the rich Brazilian biodiversity. In this sense, we introduce the use of natural cashew gum (Anacardium occidentale L.) as an active biomaterial to be used in the form of layer-by-layer films, in conjunction with phthalocyanines, which were tested as electrochemical sensors for dopamine detection. We investigated the effects of chemical composition of cashew gum from two different regions of Brazil (Piauí and Ceará states) on the physico-chemical characteristics of these nanostructures. The morphology of the nanostructures containing cashew gum was studied by atomic force microscopy which indicates that smooth films punctuated by globular features were formed that showed low roughness values. The results indicate that, independent of the origin, cashew gum stands out as an excellent film forming material with potential application in nanobiomedical devices as electrochemical sensors.
authors.affiliation: Departamento de Química, Centro de Ciências da Natureza, CCN, Universidade Federal do Piauí, UFPI, Teresina, PI, 64049-550, Brazil; Núcleo de Pesquisa em Biodiversidade e Biotecnologia, BIOTEC, Campus Parnaíba, CMRV, Universidade Federal do Piauí, UFPI, Parnaíba, PI, 64202-020, Brazil.
authors.forename: I M S
authors.initials: IM
authors.lastname: Araújo
authors.affiliation: Núcleo de Pesquisa em Biodiversidade e Biotecnologia, BIOTEC, Campus Parnaíba, CMRV, Universidade Federal do Piauí, UFPI, Parnaíba, PI, 64202-020, Brazil; Campus Parnaíba, Instituto Federal de Educação Ciência e Tecnologia do Piauí, IFPI, Parnaíba, PI, 64210-260, Brazil.
authors.forename: M F
authors.initials: MF
authors.lastname: Zampa
authors.affiliation: Departamento de Química, Centro de Ciências da Natureza, CCN, Universidade Federal do Piauí, UFPI, Teresina, PI, 64049-550, Brazil.
authors.forename: J B
authors.initials: JB
authors.lastname: Moura
authors.affiliation: Departamento de Química, Centro de Ciências da Natureza, CCN, Universidade Federal do Piauí, UFPI, Teresina, PI, 64049-550, Brazil.
authors.forename: J R
authors.initials: JR
authors.lastname: dos Santos
authors.affiliation: REQUIMTE, Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre, Porto, 4169-007, Portugal.
authors.forename: P
authors.initials: P
authors.lastname: Eaton
authors.affiliation: Grupo de Biofísica Molecular Sérgio Mascarenhas, Instituto de Física de São Carlos, IFSC, USP, São Carlos, SP, 13566-590, Brazil.
authors.forename: V
authors.initials: V
authors.lastname: Zucolotto
authors.affiliation: Núcleo de Pesquisa em Biodiversidade e Biotecnologia, BIOTEC, Campus Parnaíba, CMRV, Universidade Federal do Piauí, UFPI, Parnaíba, PI, 64202-020, Brazil.
authors.forename: L M C
authors.initials: LM
authors.lastname: Veras
authors.affiliation: Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, UFC, Fortaleza, CE, 60455-760, Brazil.
authors.forename: R C M
authors.initials: RC
authors.lastname: de Paula
authors.affiliation: Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, UFC, Fortaleza, CE, 60455-760, Brazil.
authors.forename: J P A
authors.initials: JP
authors.lastname: Feitosa
authors.affiliation: Núcleo de Pesquisa em Biodiversidade e Biotecnologia, BIOTEC, Campus Parnaíba, CMRV, Universidade Federal do Piauí, UFPI, Parnaíba, PI, 64202-020, Brazil.
authors.forename: J R S A
authors.initials: JR
authors.lastname: Leite
authors.affiliation: Núcleo de Pesquisa em Biodiversidade e Biotecnologia, BIOTEC, Campus Parnaíba, CMRV, Universidade Federal do Piauí, UFPI, Parnaíba, PI, 64202-020, Brazil.
authors.forename: C
authors.initials: C
authors.lastname: Eiras
mesh_terms: D031021:Anacardium / Q000737:chemistry*; D001672:Biocompatible Materials / Q000737:chemistry*; D015374:Biosensing Techniques / Q000379:methods; D004298:Dopamine / Q000737:chemistry; D007211:Indoles / Q000737:chemistry; D054833:Isoindoles; D049329:Nanostructures / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D007211:Indoles; D054833:Isoindoles; C013647:phthalocyanine; D004298:Dopamine