title: Epidemiologic and genetic characteristics of mumps viruses isolated in China from 1995 to 2010.
abstract: The epidemiologic and genetic characteristics of mumps viruses detected in China from 1995 to 2010 were analyzed in this study. Mumps remains endemic in China with a high overall incidence rate. The incidence of mumps in Western China was higher than that in other regions of the country. Each year, most of mumps cases occurred between April and July, but a small peak also occurred in November and December. Mumps cases primarily affected the under 15 year old age group. Virologic data demonstrated that genotype F was the predominant circulating genotype throughout China for at least 15 years and no other genotype was detected between 1995 and 2010. Analysis of sequence data from the small hydrophobic (SH) gene indicated that multiple transmission chains of genotype F were found in various provinces of China, with no apparent chronologic and geographic restriction. This is the first report describing the epidemiology of mumps and genetic characterization of mumps viruses at the national level in China.
authors.affiliation: National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Aili
authors.initials: A
authors.lastname: Cui
authors.affiliation: National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhu
authors.affiliation: Beijing Provincial Center for Disease Control and Prevention, Beijing 100013, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Chen
authors.affiliation: Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
authors.forename: Huanying
authors.initials: H
authors.lastname: Zheng
authors.affiliation: Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
authors.forename: Leng
authors.initials: L
authors.lastname: Liu
authors.affiliation: Liaoning Provincial Center for Disease Control and Prevention, Shenyang 110005, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Liaoning Provincial Center for Disease Control and Prevention, Shenyang 110005, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Ma
authors.affiliation: Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, China.
authors.forename: Changyin
authors.initials: C
authors.lastname: Wang
authors.affiliation: Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, China.
authors.forename: Xueqiang
authors.initials: X
authors.lastname: Fang
authors.affiliation: Shannxi Provincial Center for Disease Control and Prevention, Xi'an 710054, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.affiliation: Shannxi Provincial Center for Disease Control and Prevention, Xi'an 710054, China.
authors.forename: Ronghui
authors.initials: R
authors.lastname: Guan
authors.affiliation: Jilin Provincial Center for Disease Control and Prevention, Changchun 130062, China.
authors.forename: Shuang
authors.initials: S
authors.lastname: Wang
authors.affiliation: Jilin Provincial Center for Disease Control and Prevention, Changchun 130062, China.
authors.forename: Jianhui
authors.initials: J
authors.lastname: Zhou
authors.affiliation: Shanxi Provincial Center for Disease Control and Prevention, Taiyuan 030012, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zheng
authors.affiliation: Shanxi Provincial Center for Disease Control and Prevention, Taiyuan 030012, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Gao
authors.affiliation: Yunnan Provincial Center for Disease Control and Prevention, Kunming 650022, China.
authors.forename: Zhengrong
authors.initials: Z
authors.lastname: Ding
authors.affiliation: Yunnan Provincial Center for Disease Control and Prevention, Kunming 650022, China.
authors.forename: Liqun
authors.initials: L
authors.lastname: Li
authors.affiliation: Heilongjiang Provincial Center for Disease Control and Prevention, Haerbin 150030, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Bo
authors.affiliation: Heilongjiang Provincial Center for Disease Control and Prevention, Haerbin 150030, China.
authors.forename: Zhaodan
authors.initials: Z
authors.lastname: Sun
authors.affiliation: Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450016, China.
authors.forename: Zhenying
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450016, China.
authors.forename: Daxing
authors.initials: D
authors.lastname: Feng
authors.affiliation: Sichuan Provincial Center for Disease Control and Prevention, Chengdu 610041, China.
authors.forename: Jilan
authors.initials: J
authors.lastname: He
authors.affiliation: Ningxia Provincial Center for Disease Control and Prevention, Yinchuan 750004, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.affiliation: Virus Reference Department, Public Health England, London NW9 5EQ, United Kingdom.
authors.forename: Li
authors.initials: L
authors.lastname: Jin
authors.affiliation: Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
authors.forename: Paul A
authors.initials: PA
authors.lastname: Rota
authors.affiliation: National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing 102206, China. Electronic address: wenbo_xu1@aliyun.com.
authors.forename: Wenbo
authors.initials: W
authors.lastname: Xu
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D019353:Endemic Diseases; D016679:Genome, Viral; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008969:Molecular Sequence Data; D009107:Mumps / Q000453:epidemiology* / Q000635:transmission / Q000821:virology*; D009109:Mumps virus / Q000235:genetics*; D010802:Phylogeny; D014764:Viral Proteins / Q000235:genetics*
chemical_list: D014764:Viral Proteins
keywords: Epidemiology; Genetic characteristics; Mumps virus