title: An instructive case of CNS histoplasmosis in an immunocompetent host.
abstract: Histoplasma capsulatum is a dimorphic endemic fungus which infects both immunocompetent and immunocompromised hosts. Isolated CNS histoplasmosis is a rare presentation with increased risk in individuals with impaired cellular immunity, however not all patients with this condition are immunocompromised. We report a case of isolated CNS histoplasmosis in an otherwise healthy immunocompetent patient who was initially treated with Liposomal Amphotericin B followed by oral Voriconazole and later Itraconazole with significant improvement in clinical status.
authors.affiliation: Division of Infectious Diseases, University of Texas Health Science Center at Houston, 6431 Fannin, MSB 2.112, Houston, Texas 77030, USA.
authors.forename: Sweeya
authors.initials: S
authors.lastname: Ramireddy
authors.affiliation: Division of Infectious Diseases, University of Texas Health Science Center at Houston, 6431 Fannin, MSB 2.112, Houston, Texas 77030, USA.
authors.forename: Audrey
authors.initials: A
authors.lastname: Wanger
authors.affiliation: Division of Infectious Diseases, University of Texas Health Science Center at Houston, 6431 Fannin, MSB 2.112, Houston, Texas 77030, USA.
authors.forename: Luis
authors.initials: L
authors.lastname: Ostrosky
keywords: Central nervous system; Histoplasma antigen; Histoplasmosis; Meningitis; Voriconazole