title: Kidney structures differentiated from stem cells.
abstract: Generation of differentiated kidney cell types from pluripotent stem cells would be enormously useful for research and therapeutic purposes, but progress towards this goal has so far been limited. In three recent reports, mature kidney cell types and three-dimensional nephron-like structures were generated from pluripotent cells rapidly and efficiently. A detailed understanding of the signals that drive nephrogenesis proved critical for these achievements.
authors.affiliation: Renal Division, Brigham and Women's Hospital, Harvard Institute of Medicine, Room 534, 4 Blackfan Circle, Boston, Massachusetts 02115, USA.
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Humphreys
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D019070:Cell Lineage; D053595:Embryonic Stem Cells / Q000166:cytology*; D006801:Humans; D007668:Kidney / Q000166:cytology* / Q000196:embryology*