title: Characterization of flavonoids in the ethomedicine Fordiae Cauliflorae Radix and its adulterant Millettiae Pulchrae Radix by HPLC-DAD-ESI-IT-TOF-MSn.
abstract: Fordiae Cauliflorae Radix (FC, the root of Fordia cauliflora Hemsl) and Millettiae Pulchrae Radix [MP, the root of Millettia pulchra (Benth.) Kurz var. laxior (Dunn) Z. Wei], which go under the same local name of "Daluosan", have long been used in Southern China for the treatment of stroke, paralysis, dementia in children, Alzheimer's disease and other diseases. The same local name and similar functions always confuse users. To further utilize these two ethnodrugs and identify them unambiguously, an HPLC-DAD-ESI-IT-TOF-MSn method was developed to separate and characterize the flavonoids in FC and MP. A total of 41 flavonoids were detected, of which six compounds were identified by comparing their retention time and MS data with those of the reference standards, and the others were tentatively identified based on their tandem mass spectrometry data obtained in the positive ion detection mode. Nineteen of these characterized compounds are reported from these two plants for the first time.
authors.forename: Lan-Lan
authors.initials: LL
authors.lastname: Fan
authors.forename: Tao
authors.initials: T
authors.lastname: Yi
authors.forename: Feng
authors.initials: F
authors.lastname: Xu
authors.forename: Ya-Zhou
authors.initials: YZ
authors.lastname: Zhang
authors.forename: Jian-Ye
authors.initials: JY
authors.lastname: Zhang
authors.forename: Dian-Peng
authors.initials: DP
authors.lastname: Li
authors.forename: Yang-Jiao
authors.initials: YJ
authors.lastname: Xie
authors.forename: Shan-Ding
authors.initials: SD
authors.lastname: Qin
authors.affiliation: School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. hbchen@hkbu.edu.hk.
authors.forename: Hu-Biao
authors.initials: HB
authors.lastname: Chen
mesh_terms: D002599:Chalcone / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D007887:Fabaceae / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry*; D033641:Millettia / Q000737:chemistry; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D053719:Tandem Mass Spectrometry
chemical_list: D005419:Flavonoids; D002599:Chalcone