title: Unusual benign polypoid and papular neoplasms and tumor-like lesions of the vulva.
abstract: We aimed to investigate the prevalence and spectrum of unusual benign neoplasms and tumor-like lesions presenting as vulvar polyps and papules, to study their clinical, pathologic, hormonal, and developmental features and whether they have important associations with other pathologic lesions or clinical diseases. We conducted a retrospective review study of 115 vulvar specimens over 7 years. Common lesions, for example, fibroepithelial polyps, skin tags, papillomas, abscesses, viral warts and common cysts, were excluded. We found 21 cases (18%) with uncommon benign vulvar lesions. They included 7 epithelial cysts, 3 vascular lesions, 3 glandular neoplasms, 3 endometrioses, 1 caruncle, 1 pilonidal sinus, 1 prolapsed urethra, 1 seborrheic keratosis, and 1 granular cell tumor. The age range was between 1 and 64 years with a mean age of 33 years. Most (86%) were 2.5 cm or less. Many were asymptomatic incidental pathologic findings that can be missed clinically. Nine cases have important clinical associations or coexisting incidental pathologic lesions. Some lesions demonstrated hormone receptors. Some were clinically confused with fibroepithelial polyps, abscesses, warts, melanocytic lesions, and tumors. In conclusion, although the vulva is a small compartment, its developmental and histologic complexity can result in a variety of unusual and rare benign polypoid and papular lesions, some unique to the vulva, which might present diagnostic challenges to the clinicians and pathologists. In addition, many bear controversy regarding their histogenesis and origin of development in the vulva.
authors.affiliation: Pathology Section, Rashid Hospital, Dubai, UAE. Electronic address: badraah009@yahoo.com.
authors.forename: Badr
authors.initials: B
authors.lastname: AbdullGaffar
authors.affiliation: Histopathology Department, Dubai Hospital, Dubai, UAE.
authors.forename: Tasnim R
authors.initials: TR
authors.lastname: Keloth
authors.affiliation: Histology Unit, Dubai Hospital, Dubai, UAE.
authors.forename: Lakshmiah G
authors.initials: LG
authors.lastname: Raman
authors.affiliation: Gynecology Department, Dubai Hospital, Dubai, UAE.
authors.forename: Suaad
authors.initials: S
authors.lastname: Mahmood
authors.affiliation: Gynecology Department, AlWasl Hospital, Dubai, UAE.
authors.forename: Amal
authors.initials: A
authors.lastname: Almulla
authors.affiliation: Pediatrics Surgery, AlWasl Hospital, Dubai, UAE.
authors.forename: Mamoun
authors.initials: M
authors.lastname: AlMarzouqi
authors.affiliation: Urology Department, Dubai Hospital, Dubai, UAE.
authors.forename: Salam
authors.initials: S
authors.lastname: Al-Hasani
mesh_terms: D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008875:Middle Aged; D011127:Polyps / Q000473:pathology*; D012189:Retrospective Studies; D014844:Vulva / Q000473:pathology; D014845:Vulvar Diseases / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000473:pathology*; D055815:Young Adult
keywords: Benign; Cysts; Neoplasms; Papules; Polyps; Tumor-like lesions; Vulva