title: Amperometric glucose sensor based on enhanced catalytic reduction of oxygen using glucose oxidase adsorbed onto core-shell Fe3O4@silica@Au magnetic nanoparticles.
abstract: Monodisperse Fe3O4 magnetic nanoparticles (NPs) were prepared under facile solvothermal conditions and successively functionalized with silica and Au to form core/shell Fe3O4@silica@Au NPs. Furthermore, the samples were used as matrix to construct a glucose sensor based on glucose oxidase (GOD). The immobilized GOD retained its bioactivity with high protein load of 3.92×10(-9) mol·cm(-2), and exhibited a surface-controlled quasi-reversible redox reaction, with a fast heterogeneous electron transfer rate of 7.98±0.6 s(-1). The glucose biosensor showed a broad linear range up to 3.97 mM with high sensitivity of 62.45 μA·mM(-1) cm(-2) and fast response (less than 5s).
authors.affiliation: College of Geography and Environmental Science, College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China; Key Laboratory of Green Chemical Media and Reactions, Ministry of Education; School of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453007, China.
authors.forename: Ai-Jun
authors.initials: AJ
authors.lastname: Wang
authors.affiliation: College of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, China.
authors.forename: Yong-Fang
authors.initials: YF
authors.lastname: Li
authors.affiliation: Key Laboratory of Green Chemical Media and Reactions, Ministry of Education; School of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453007, China.
authors.forename: Zhong-Hua
authors.initials: ZH
authors.lastname: Li
authors.affiliation: College of Geography and Environmental Science, College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China; Key Laboratory of Green Chemical Media and Reactions, Ministry of Education; School of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453007, China.
authors.forename: Jiu-Ju
authors.initials: JJ
authors.lastname: Feng
authors.affiliation: Key Laboratory of Green Chemical Media and Reactions, Ministry of Education; School of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453007, China.
authors.forename: Yan-Li
authors.initials: YL
authors.lastname: Sun
authors.affiliation: College of Geography and Environmental Science, College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China.
authors.forename: Jian-Rong
authors.initials: JR
authors.lastname: Chen
mesh_terms: D000327:Adsorption; D015374:Biosensing Techniques / Q000379:methods; D002384:Catalysis; D005290:Ferric Compounds / Q000737:chemistry*; D005296:Ferrous Compounds / Q000737:chemistry*; D005947:Glucose / Q000737:chemistry*; D005949:Glucose Oxidase / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D005290:Ferric Compounds; D005296:Ferrous Compounds; D058185:Magnetite Nanoparticles; C000499:ferric oxide; D006046:Gold; D012822:Silicon Dioxide; D005949:Glucose Oxidase; C034236:ferrous oxide; D005947:Glucose; D010100:Oxygen