title: [Hepcidin as a central mediator of anemia of chronic diseases associated with obesity].
abstract: Recent evidence suggests that obesity-related inflammation may play a central role in hepcidin regulation. Hepcidin is a key regulator ofiron homeostasis and has now been suggested as a central mediator ofiron metabolism disorders involved in the pathogenesis of anemia of chronic disease. In this review, we focus on subclinical inflammation in obesity and its effect on hepcidin levels, as the most plausible explanation for the relationship between anemia of chronic disease and obesity.
authors.affiliation: Laboratorio de Micronutriente, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile, Santiago, Chile, pia.villarroel@inta.uchile.cl.
authors.forename: Pía
authors.initials: P
authors.lastname: Villarroel H
authors.affiliation: Laboratorio de Micronutriente, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile, Santiago, Chile, pia.villarroel@inta.uchile.cl.
authors.forename: Miguel
authors.initials: M
authors.lastname: Arredondo O
authors.affiliation: Laboratorio de Micronutriente, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile, Santiago, Chile, pia.villarroel@inta.uchile.cl.
authors.forename: Manuel
authors.initials: M
authors.lastname: Olivares G
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000150:complications* / Q000378:metabolism*; D002908:Chronic Disease; D064451:Hepcidins / Q000097:blood / Q000378:metabolism*; D006706:Homeostasis; D006801:Humans; D007249:Inflammation / Q000097:blood / Q000150:complications* / Q000378:metabolism; D009765:Obesity / Q000097:blood / Q000150:complications* / Q000378:metabolism
chemical_list: D064451:Hepcidins