title: Anaplastic Solitary plasmacytoma of mandible, masquerading as sarcoma.
abstract: Plasma cell neoplasm is characterized by a monoclonal neoplastic proliferation of plasma cells and solitary plasmocytoma of bone (SPB) is a localized form. It usually occurs in vertebrae and secondarily in long bones. Its presence in mandible is extremely rare event. A 48-year-old man consulted to our clinic with a chief complaint of pain in his mandible. Radiography revealed a destructive lesion in body and ramus. The initial pathologic evaluation revealed a high grade pleomorphic neoplasm. The diagnosis was confirmed by immunohistochemical markers. Overall, plasmacytoma with anaplastic features can be confused with high grade sarcoma clinically and histologically.
authors.affiliation: Mohamad Javad Ashraf, MD, Department of Pathology, Shiraz University of Medical Science, Shiraz, Iran.
authors.forename: Mohamad Javad
authors.initials: MJ
authors.lastname: Ashraf
authors.affiliation: Negar Azarpira, MD, Transplant Research Center, Shiraz University of Medical Science, Shiraz, Iran.
authors.forename: Negar
authors.initials: N
authors.lastname: Azarpira
authors.affiliation: Bijan Khademi, MD, Department of Otolaryngology, Shiraz University of Medical Science, Shiraz, Iran.
authors.forename: Bijan
authors.initials: B
authors.lastname: Khademi
keywords: Mandible; Plasmacytoma; Radiology