title: Skin viscoelasticity studied in vitro by microprobe-based techniques.
abstract: Time-dependent deformation of porcine skin was studied in vitro using specialized microprobe instruments. The deformation behavior of stratum corneum, dermis, and whole skin is examined in the context of results of creep strain, elastic stiffness, and viscoelastic constants obtained in terms of the hold time, loading/unloading rate, and maximum indentation depth (load). Skin time-dependent deformation is significantly influenced by dermis viscoelasticity up to a critical indentation depth (load) beyond which it is controlled by the outermost hard epidermis, particularly stratum corneum. Skin viscoelastic behavior under constant load (creep) and constant displacement (stress relaxation) is interpreted in the light of phenomenological observations and experimental trends.
authors.affiliation: Department of Mechanical Engineering, University of California, Berkeley, CA 94720, USA.
authors.forename: T
authors.initials: T
authors.lastname: Jee
authors.affiliation: Department of Mechanical Engineering, University of California, Berkeley, CA 94720, USA. Electronic address: kyriakos@me.berkeley.edu.
authors.forename: K
authors.initials: K
authors.lastname: Komvopoulos
mesh_terms: D000818:Animals; D003430:Cross-Sectional Studies; D020405:Dermis / Q000473:pathology / Q000502:physiology*; D004548:Elasticity; D004817:Epidermis / Q000502:physiology; D012879:Skin Physiological Phenomena; D013314:Stress, Mechanical; D013552:Swine; D014783:Viscosity
keywords: Deformation; Indentation; Skin; Stiffness; Viscoelasticity