title: Antibacterial potential of hydroalcoholic extracts of triphala components against multidrug-resistant uropathogenic bacteria--a preliminary report.
abstract: "Triphala", the Ayurvedic wonder is used traditionally for the treatment of different types of diseases since antiquity. The hydroalcoholic extracts of the three components of Triphala powder demonstrated varying degrees of strain specific antibacterial activity against multidrug-resistant uropathogenic bacteria. Terminalia chebula fruit extract was active against all the test isolates followed by Terminalia belerica and Emblica officinalis. There was a close association between antibacterial activity and total phenolic content of Triphala components.The test plant extracts were also found to be non-toxic on human erythrocyte membrane at recommended and even higher doses. The preliminary results of the present study may help in developing effective and safe antimicrobial agents from Triphala components for the treatment of urinary tract infections caused by multidrug-resistant bacteria.
authors.affiliation: Department of Microbiology, Institute of Post Graduate Medical Education and Research, 244, AJC Bose Road, Kolkata 700 020, India. anwesa.bag@gmail.com
authors.forename: Anwesa
authors.initials: A
authors.lastname: Bag
authors.forename: Subir Kumar
authors.initials: SK
authors.lastname: Bhattacharyya
authors.affiliation: Department of Microbiology, Institute of Post Graduate Medical Education and Research, 244, AJC Bose Road, Kolkata 700 020, India.
authors.forename: Nishith Kumar
authors.initials: NK
authors.lastname: Pal
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D024881:Drug Resistance, Bacterial; D018432:Drug Resistance, Multiple; D000431:Ethanol; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D001743:Urinary Bladder / Q000382:microbiology*
chemical_list: D010936:Plant Extracts; C520904:triphala; D000431:Ethanol