title: Behçet's disease accompanied by myelodysplastic syndrome with trisomy 8: two case reports and a review of 15 Japanese cases.
abstract: Abstract We describe two cases of Behçet's disease associated with myelodysplastic syndrome (MDS) with trisomy 8. Both cases developed ulceration in the cecum as a gastrointestinal complication of Behçet's disease, after a diagnosis of MDS. We summarized recent case reports of Behçet's disease associated with myelodysplastic syndrome, and studied the clinical manifestations. Most cases showed trisomy 8 as a chromosomal abnormality. Gastrointestinal involvement without eye lesions seems to be characteristic of Behçet's disease associated with MDS.
authors.affiliation: Division of Rheumatology, Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba , 1-1-1 Tennodai, Tsukuba 305-8575 , Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Adachi
authors.forename: A
authors.initials: A
authors.lastname: Tsutsumi
authors.forename: H
authors.initials: H
authors.lastname: Murata
authors.forename: H
authors.initials: H
authors.lastname: Takemura
authors.forename: Y
authors.initials: Y
authors.lastname: Chino
authors.forename: R
authors.initials: R
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Ebitsuka
authors.forename: T
authors.initials: T
authors.lastname: Sumida