title: Do different arterial stiffness parameters provide similar information in high-risk patients for coronary artery disease?
abstract: OBJECTIVE
  The aim of our study was to compare the values of brachial-ankle pulse wave velocity (baPWV) measured with two different non-invasive methods as predictors of coronary artery disease (CAD) in patients who had undergone coronary angiography.
  
  
  METHODS
  From 6373 patients who visited our laboratory for non-invasive procedures, we enrolled 965 consecutive patients undergoing coronary angiography. Data for baPWV and peripheral augmentation index (pAI) were recorded. CAD was defined as greater than 50% stenosis of a major epicardial artery in a coronary angiogram. In addition, the severity of CAD was classified as: none/minimal or 1-, 2-, or 3-vessel disease, based on previous or current angiographic findings.
  
  
  RESULTS
  Among 965 subjects, the mean age was 63.7±11.6 years, and 58.2% were male. Compared with subjects without CAD disease, those with CAD showed higher values of baPWV (16.6±3.5 m/sec vs. 15.9±3.4 m/sec, p<0.001), and lower values of pAI (73.5±15.9% vs. 76.0±15.7%, p=0.01). When the severity of CAD was expressed as none/minimal or 1-, 2-, or 3-vessel disease, there was a significant association between the extent of CAD and baPWV (p<0.001). In univariate analysis, high PWV and low pAI were associated with an increased prevalence of CAD (p<0.001).
  
  
  CONCLUSIONS
  Increased baPWV and decreased pAI were associated with the presence of CAD in the elderly.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Kyung Min
authors.initials: KM
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Byung-Su
authors.initials: BS
authors.lastname: Yoo
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Anna
authors.initials: A
authors.lastname: Ko
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Jeong Min
authors.initials: JM
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Hyun Sik
authors.initials: HS
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Jun-Won
authors.initials: JW
authors.lastname: Lee
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Jang-Young
authors.initials: JY
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Young Jin
authors.initials: YJ
authors.lastname: Youn
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Sung Gyun
authors.initials: SG
authors.lastname: Ahn
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Seung-Hwan
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Junghan
authors.initials: J
authors.lastname: Yoon
keywords: Arterial stiffness; Coronary artery disease; Pulse wave velocity