title: Association of IgA secretory component sialylation with leucocytospermia of infertile men - a pilot study.
abstract: The aim of our pilot study was to check whether the differences in IgA secretory component (SC) sialylation are associated with leucocytospermia. In normozoospermic and leucocytospermic seminal plasmas, 78-kDa and 63-kDa SC immunoreactive bands were observed. The SC sialylation was analysed by lectin blotting, using sialo-specific lectins MAA (Maackia amurensis agglutinin) and SNA (Sambucus nigra agglutinin). Specific reactivity of 63-kDa SC with MAA and SNA was higher than 78-kDa SC in both analysed seminal groups. The analysis of seminal SC sialylation might be a valuable diagnosis tools for the evaluation of fertility problems related with leucocytospermia.
authors.affiliation: Department of Chemistry and Immunochemistry, Wrocław Medical University, Wrocław, Poland.
authors.forename: E M
authors.initials: EM
authors.lastname: Kratz
authors.forename: M
authors.initials: M
authors.lastname: Ferens-Sieczkowska
mesh_terms: D000328:Adult; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism*; D007248:Infertility, Male / Q000378:metabolism*; D037102:Lectins / Q000378:metabolism; D007962:Leukocytes / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012635:Secretory Component / Q000378:metabolism*; D012661:Semen / Q000378:metabolism*
chemical_list: D007070:Immunoglobulin A; D037102:Lectins; D012635:Secretory Component
keywords: Leucocytospermia; male fertility; secretory component of IgA; sialylation