title: Deep vein thrombosis in patients with severe motor and intellectual disabilities.
abstract: Most patients with severe motor and intellectual disabilities (SMID) have restricted mobility capability and have been bedridden for long periods because of paralysis of the extremities caused by abnormal muscular tonicity due to cerebral palsy and developmental disabilities, and such patients are associated with a high risk for the complications of deep vein thrombosis (DVT). Here, we report 8 patients (34.8%) with DVT among 23 patients with SMID during prolonged bed rest. However, we did not detect thrombosis in the soleal veins, finding it mostly in the superficial femoral and common femoral veins. Regarding laboratory data for the coagulation system, there were no cases with D-dimer above 5 µg/ml. Concerning sudden death in patients with SMID, we have to be very careful of the possibility of pulmonary thromboembolism due to DVT. Therefore, we should consider the particularities of an underdeveloped vascular system from underlying diseases for the evaluation of DVT in patients with SMID. A detailed study of DVT as a vascular complication is very important for smooth medical care of SMID and compression Doppler ultrasonography of the lower extremities, as noninvasive examination, is very helpful. (English translation of Jpn J Phlebol 2012; 23: 17-24).
authors.affiliation: Department of Pediatrics, National Hospital Organization Yanai Medical Center, Yanai, Yamaguchi, Japan.
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Ohmori
authors.affiliation: Department of Pediatrics, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Ochi
authors.affiliation: Department of Pediatrics, Tokyo Metropolitan Fuchu Center for the Disabled, Fuchu, Tokyo, Japan.
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Tanuma
authors.affiliation: Department of Neurology, National Hospital Organization Yanai Medical Center, Yanai, Yamaguchi, Japan.
authors.forename: Eiichi
authors.initials: E
authors.lastname: Ohnuki
authors.affiliation: Department of Neurology, National Hospital Organization Yanai Medical Center, Yanai, Yamaguchi, Japan.
authors.forename: Masami
authors.initials: M
authors.lastname: Yamasaki
authors.affiliation: Department of Laboratory, National Hospital Organization Yanai Medical Center, Yanai, Yamaguchi, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Takesue
authors.affiliation: Department of Medical Laboratory, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan.
authors.forename: Miki
authors.initials: M
authors.lastname: Kan
authors.affiliation: Department of Internal Medicine, National Hospital Organization Yanai Medical Center, Yanai, Yamaguchi, Japan.
authors.forename: Nobuo
authors.initials: N
authors.lastname: Matsumoto
authors.affiliation: Department of Surgery, National Hospital Organization Yanai Medical Center, Yanai, Yamaguchi, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Sumimoto
authors.affiliation: Department of Neurology, National Hospital Organization Yanai Medical Center, Yanai, Yamaguchi, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Harada
keywords: deep vein thrombosis (DVT); pulmonary thromboembolism; severe motor and intellectual disabilities (SMID); ultrasonography