title: MRI role in morphological and functional assessment of the levator ani muscle: use in patients affected by stress urinary incontinence (SUI) before and after pelvic floor rehabilitation.
abstract: OBJECTIVE
  Pelvic floor dysfunctions affect a very high proportion of female population. Magnetic resonance imaging is the only technique able to provide a multiplanar overview of pelvic organs and muscles without the use of ionizing radiation. The aim of our prospective study is to objectively evaluate the effectiveness of perineal re-education applying MR technique.
  
  
  METHODS
  22 patients affected by stress urinary incontinence were enrolled in our prospective study. They underwent urogynaecological, urodynamic examinations, and a questionnaire about symptoms (ICIQ-UI) to investigate the degree of their interference with daily activities. Then they underwent a morphological and dynamic MR exam.
  
  
  RESULTS
  The pre-perineal rehabilitation MR examinations showed an asymmetry of the levator ani muscle in 87% of patients; the remaining 13% showed a muscular bilateral volume reduction. In the group with unilateral defect, the muscle total volume had values between 15 and 21 cm3. Its overall volume was 34.2% smaller on the defective side (9.28±0.26 cm3) compared to the normal side (12.64±12.31 cm3, P<0.001). In patients with a bilateral impairment, the muscle was replaced by fibro-fatty tissue, without a significant asymmetry between the two sides. The post-perineal rehabilitation MR tests showed three different degrees of response to therapy, with a "complete response" found in 67% of patients and no response in 13%.
  
  
  CONCLUSIONS
  MR is an useful tool in the management of patients affected by stress urinary incontinence with indication for perineal rehabilitation. Its objective data allow to distinguish different types of response to therapy and, consequently, different outcomes in terms of additional treatments.
authors.affiliation: Department of Radiology, Campus Bio-Medico Hospital, Rome, Italy. Electronic address: r.delvescovo@unicampus.it.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Del Vescovo
authors.affiliation: Department of Radiology, Campus Bio-Medico Hospital, Rome, Italy. Electronic address: c.piccolo@unicampus.it.
authors.forename: Claudia Lucia
authors.initials: CL
authors.lastname: Piccolo
authors.affiliation: Department of Radiology, Campus Bio-Medico Hospital, Rome, Italy. Electronic address: nico.dvecchia@libero.it.
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Della Vecchia
authors.affiliation: Department of Radiology, Campus Bio-Medico Hospital, Rome, Italy. Electronic address: f.giurazza@unicampus.it.
authors.forename: Francesco
authors.initials: F
authors.lastname: Giurazza
authors.affiliation: Department of Radiology, Campus Bio-Medico Hospital, Rome, Italy. Electronic address: r.cazzato@unicampus.it.
authors.forename: Roberto Luigi
authors.initials: RL
authors.lastname: Cazzato
authors.affiliation: Department of Radiology, Campus Bio-Medico Hospital, Rome, Italy. Electronic address: r.grasso@unicampus.it.
authors.forename: Rosario Francesco
authors.initials: RF
authors.lastname: Grasso
authors.affiliation: Department of Radiology, Campus Bio-Medico Hospital, Rome, Italy. Electronic address: b.zobel@unicampus.it.
authors.forename: Bruno Beomonte
authors.initials: BB
authors.lastname: Zobel
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology*; D009929:Organ Size; D017773:Pelvic Floor / Q000473:pathology*; D011446:Prospective Studies; D020127:Recovery of Function; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016896:Treatment Outcome; D014550:Urinary Incontinence, Stress / Q000175:diagnosis* / Q000534:rehabilitation*
keywords: Levator ani; MRI; Pelvic floor diseases; Perineal-rehabilitation; Stress urinary incontinence