title: [Control of bovine hypodermosis in Switzerland; looking back].
abstract: For many years, hypodermosis control - which started in the 1920's - was unsatisfactory, partly due to a lack of efficacy or a too high toxicity of the available products. An improved control became possible with the introduction (1957) of the organophosphate Metrifonate (Neguvon®, Bayer AG). Subsequent large-scale campaigns according to the Federal Ordinance on epizootic diseases (1967) quite reduced hypodermosis in Switzerland. However, due to a limited use of the product (only young and alpine-grazing cattle were allowed to be treated, administratively indicated maximum dose, side-effects) and its incomplete efficacy, a full control was not possible. The decision to maintain hypodermosis as a "notifiable" disease then allowed further epidemiological studies. In 2000/2001 a concerted action in close cooperation with the cantonal veterinarians allowed a consequent and systematic treatment of all cattle in all endemic areas by the large-scale use of Eprinomectin (Eprinex®, Merial Inc.) for dairy cattle and of Ivermectin (Merial Inc.) as microdose "off-label" for young cattle has led to a rapid and sustainable success.
authors.affiliation: 1Institut de Biologie, Université de Neuchâtel, 2Vergleichende Tropenmedizin und Parasitologie, Tierärztliche Fakultät, Ludwig-Maximilians-Universität München, 3Cabinet Vétérinaire Sieber & Charbon Sàrl, Estavayer-le-Lac.
authors.forename: K
authors.initials: K
authors.lastname: Pfister
authors.affiliation: 1Institut de Biologie, Université de Neuchâtel, 2Vergleichende Tropenmedizin und Parasitologie, Tierärztliche Fakultät, Ludwig-Maximilians-Universität München, 3Cabinet Vétérinaire Sieber & Charbon Sàrl, Estavayer-le-Lac.
authors.forename: J -L
authors.initials: J-
authors.lastname: Charbon
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000266:history / Q000517:prevention & control*; D049673:History, 20th Century; D049674:History, 21st Century; D007000:Hypodermyiasis / Q000266:history / Q000517:prevention & control / Q000662:veterinary*; D007306:Insecticides / Q000627:therapeutic use; D007559:Ivermectin / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D007306:Insecticides; D007559:Ivermectin; C101434:eprinomectin
keywords: Bekämpfung; Epidemiologie; Eprinomectin; Hypodermose; Schweiz; Switzerland; control; epidemiology; hypodermosis