title: Laryngeal neuroma in multiple endocrine neoplasia type 2B.
abstract: Multiple endocrine neoplasia (MEN) type 2 syndrome is an autosomal dominant inherited disease caused by mutations of the RET proto-oncogene, and is clinically divided into three phenotypes: MEN2A, MEN2B, and familial medullary thyroid carcinoma. Although multiple mucosal neuromas are commonly observed in patients with MEN2B, there are only a few reports of laryngeal neuroma. We present here a rare case of laryngeal mucosal neuromas with MEN2B.
authors.affiliation: Department of Otorhinolaryngology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Japan.
authors.forename: Naomi
authors.initials: N
authors.lastname: Kudo
authors.affiliation: Department of Otorhinolaryngology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Japan. Electronic address: amatsu@cc.hirosaki-u.ac.jp.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Matsubara
authors.affiliation: Department of Otorhinolaryngology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Japan.
authors.forename: Takahisa
authors.initials: T
authors.lastname: Abe
authors.affiliation: Department of Otorhinolaryngology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Japan.
authors.forename: Taku
authors.initials: T
authors.lastname: Inoue
authors.affiliation: Department of Otorhinolaryngology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Japan.
authors.forename: Junko
authors.initials: J
authors.lastname: Takahata
mesh_terms: D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D018814:Multiple Endocrine Neoplasia Type 2b / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009463:Neuroma / Q000473:pathology*; D000090063:Proto-Oncogene Mas; D055815:Young Adult
keywords: Laryngeal neuroma; Mucosal neuroma; Multiple endocrine neoplasia