title: [Adherence to treatment, by active ingredient, in patients over 65 years on multiple medication].
abstract: OBJECTIVE
  To assess the level of adherence, by active ingredient, to treatment and associated factors in polymedicated patients over 65 years-old.
  
  
  METHODS
  Observational, descriptive and cross-sectional study over polymedicated patients over 65 years of the Costa del Sol Health District and the North Malaga Health Area. The study was performed between January 2011 and September 2012 on 375 subjects obtained by simple random sampling from lists provided by each health centre. Data was collected by means of an interview with structured questions. Informed consent was given and signed by all patients before interview.
  
  
  METHODS
  Main results variable adherence to treatment (Morisky-Green's test).
  Prescription by active ingredient, socio-demographic variables, health care centre variables, and treatment associated variables. A descriptive analysis of variables was performed. Statistical inference was determined using univariate analysis (t test of Student or Mann-Whitney U, and Chi-squared), and controlling for confounding factors by multivariate analysis (linear and logistic regression).
  
  
  RESULTS
  The result for therapeutic compliance was 51.7%. No statistically significant differences were observed as regards sex and age. A relationship was found in those who resided in rural areas (P=.001), lived with family (P<.05), and were not at risk of suffering from anxiety (P=.046).
  
  
  CONCLUSIONS
  We found similar patient adherence to treatment despite the prescribing generic drugs. Failure to therapeutic compliance was greater in those patients who lived by themselves, in a city close to the coast, or in those patients who were at risk of suffering from anxiety.
authors.affiliation: Área Sanitaria Norte de Málaga, Málaga, España.
authors.forename: Antonio J
authors.initials: AJ
authors.lastname: Núñez Montenegro
authors.affiliation: San Miguel, Distrito Sanitario Costa del Sol, Torremolinos, Málaga, España.
authors.forename: Alonso
authors.initials: A
authors.lastname: Montiel Luque
authors.affiliation: La Roca, Distrito Sanitario Málaga, Málaga, España.
authors.forename: Esther
authors.initials: E
authors.lastname: Martín Aurioles
authors.affiliation: Antequera Estación, Área Sanitaria Norte de Málaga, Málaga, España.
authors.forename: Barbara
authors.initials: B
authors.lastname: Torres Verdú
authors.affiliation: Archidona, Área Sanitaria Norte de Málaga, Málaga, España.
authors.forename: Celinda
authors.initials: C
authors.lastname: Lara Moreno
authors.affiliation: Facultad de Ciencias de la Salud, Universidad de Málaga, Málaga, España. Electronic address: antonionm14@enfermundi.com.
authors.forename: José Antonio
authors.initials: JA
authors.lastname: González Correa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D019338:Polypharmacy; D016903:Drug Monitoring
keywords: Active ingredient; Adherence; Adherencia terapéutica; Anciano; Elderly; Multiple medication; Patient safety; Polimedicado; Principio activo; Seguridad del paciente