title: Cardiopulmonary bypass in pregnancy.
abstract: Cardiac surgery carried out on cardiopulmonary bypass (CPB) in a pregnant woman is associated with poor neonatal outcomes although maternal outcomes are similar to cardiac surgery in non-pregnant women. Most adverse maternal and fetal outcomes from cardiac surgery during pregnancy are attributed to effects of CPB. The CPB is associated with utero-placental hypoperfusion due to a number of factors, which may translate into low fetal cardiac output, hypoxia and even death. Better maternal and fetal outcomes may be achieved by early pre-operative optimization of maternal cardiovascular status, use of perioperative fetal monitoring, optimization of CPB, delivery of a viable fetus before the operation and scheduling cardiac surgery on an elective basis during the second trimester.
authors.affiliation: Department of Anesthesia, Saket City Hospital, Saket, New Delhi, India.
authors.forename: Mukul Chandra
authors.initials: MC
authors.lastname: Kapoor
mesh_terms: D000328:Adult; D000777:Anesthetics; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass / Q000379:methods*; D005112:Extracorporeal Circulation; D005260:Female; D005318:Fetal Heart / Q000502:physiology; D005865:Gestational Age; D006324:Heart Arrest, Induced; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D016343:Monitoring, Intraoperative / Q000379:methods; D011247:Pregnancy / Q000502:physiology*; D014599:Uterus / Q000502:physiology
chemical_list: D000777:Anesthetics