title: Scleredema: report of a case.
abstract: Abstract We describe a patient with scleredema. Thickened skin was observed in the posterior region of her neck, shoulders, and back. A skin biopsy revealed thickened dermis consisting of numerous thickened collagen bundles. Laboratory data revealed that she was suffering from diabetes mellitus (DM). The skin lesions ameliorated within a period of one month when her DM condition was controlled by oral hypoglycemics. Scleredema is a rare connective tissue disorder; its cutaneous manifestation should be distinguished from scleroderma.
authors.affiliation: Department of Rheumatology and Internal Medicine, Juntendo University School of Medicine , 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421 , Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Kumagai
authors.forename: T
authors.initials: T
authors.lastname: Ebitsuka
authors.forename: T
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Y
authors.initials: Y
authors.lastname: Takasaki
authors.forename: H
authors.initials: H
authors.lastname: Hashimoto