title: Borderline tumours of the ovary, current controversies regarding their diagnosis and treatment.
abstract: Borderline ovarian tumours generally affect women of reproductive age. The positive prognosis is related to the fact that over 80% of cases are diagnosed at an early stage of the disease. Although radical surgery is the standard of care for this disease, fertility-sparing surgery can be performed in selected cases. Since it was first described in 1929, the knowledge of the molecular and histologic characteristics has been significantly improved. In this review, advances in the clinical behaviour, pathologic characteristics, prognostics factors, and different strategies of treatment are discussed.
authors.affiliation: Gynaecology Oncology Programme, Clara Campal Comprehensive Cancer Centre, HM Hospitals, Madrid 28050, Spain.
authors.forename: María Guadalupe
authors.initials: MG
authors.lastname: Patrono
authors.affiliation: Gynaecology Oncology Programme, Clara Campal Comprehensive Cancer Centre, HM Hospitals, Madrid 28050, Spain.
authors.forename: Lucas
authors.initials: L
authors.lastname: Minig
authors.affiliation: Gynaecology Oncology Programme, Medical Oncology, Comprehensive Oncology Centre Clara Campal, HM Hospitals, Madrid 28050, Spain.
authors.forename: Ivan
authors.initials: I
authors.lastname: Diaz-Padilla
authors.affiliation: Gynaecology Oncology Programme, Medical Oncology, Comprehensive Oncology Centre Clara Campal, HM Hospitals, Madrid 28050, Spain.
authors.forename: Nuria
authors.initials: N
authors.lastname: Romero
authors.affiliation: Gynaecology Oncology Programme, Medical Oncology, Comprehensive Oncology Centre Clara Campal, HM Hospitals, Madrid 28050, Spain.
authors.forename: Juan Francisco
authors.initials: JF
authors.lastname: Rodriguez Moreno
authors.affiliation: Gynaecology Oncology Programme, Medical Oncology, Comprehensive Oncology Centre Clara Campal, HM Hospitals, Madrid 28050, Spain.
authors.forename: Jesus
authors.initials: J
authors.lastname: Garcia-Donas
keywords: borderline ovarian tumour; conservative treatment of fertility; gynaecological cancer; ovarian cancer surgery