title: Glucocorticoids for acute viral bronchiolitis in infants and young children.
abstract: OBJECTIVE
  Are glucocorticoids, alone or combined with bronchodilators, associated with reduced admission rates, length of stay, or improvements in clinical severity scores without increased adverse effects in infants and young children with acute viral bronchiolitis?
  
  
  CONCLUSIONS
  There is no consistent clinically relevant association of single therapy with systemic or inhaled glucocorticoids and improved outcomes in either outpatient or inpatient settings. Exploratory evidence suggests that combined glucocorticoids and nebulized epinephrine may be associated with lower hospitalization rates in outpatients, but these findings must be interpreted cautiously.
authors.affiliation: Department of Pediatrics, Santa Maria Hospital, Lisbon Academic Medical Centre, Portugal2Clinical Pharmacology Unit, Instituto de Medicina Molecular, University of Lisbon, Portugal.
authors.forename: Ricardo M
authors.initials: RM
authors.lastname: Fernandes
authors.affiliation: Department of Pediatrics, Alberta Research Centre for Health Evidence, University of Alberta, Edmonton, Canada.
authors.forename: Lisa
authors.initials: L
authors.lastname: Hartling
mesh_terms: D001990:Bronchiolitis, Viral / Q000188:drug therapy*; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans
chemical_list: D005938:Glucocorticoids