title: Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab.
abstract: Trastuzumab is a monoclonal antibody targeting HER-2. HER-2 overexpression has been described in gallbladder cancer and in cholangiocarcinoma. This report describes the first case of a patient with HER-2 overexpressing metastatic gallbladder adenocarcinoma and responding radiographically and biochemically to trastuzumab alone.
authors.affiliation: Washington University School of Medicine, Department of Oncology, St Louis, MO, USA.
authors.forename: Steven
authors.initials: S
authors.lastname: Sorscher
keywords: HER-2 overexpression; metastatic gallbladder adenocarcinoma; trastuzumab