title: Mechanisms of exercise-induced cardioprotection.
abstract: Myocardial ischemia-reperfusion (IR) injury can cause ventricular cell death and is a major pathological event leading to morbidity and mortality in those with coronary artery disease. Interestingly, as few as five bouts of exercise on consecutive days can rapidly produce a cardiac phenotype that resists IR-induced myocardial injury. This review summarizes the development of exercise-induced cardioprotection and the mechanisms responsible for this important adaptive response.
authors.affiliation: Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida; and.
authors.forename: Scott K
authors.initials: SK
authors.lastname: Powers
authors.forename: Ashley J
authors.initials: AJ
authors.lastname: Smuder
authors.forename: Andreas N
authors.initials: AN
authors.lastname: Kavazis
authors.forename: John C
authors.initials: JC
authors.lastname: Quindry
mesh_terms: D000818:Animals; D003324:Coronary Artery Disease / Q000517:prevention & control; D015444:Exercise / Q000502:physiology*; D006321:Heart / Q000502:physiology* / Q000503:physiopathology; D006801:Humans; D024101:Mitochondrial Proteins / Q000378:metabolism; D015428:Myocardial Reperfusion Injury / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D009206:Myocardium / Q000378:metabolism*
chemical_list: D024101:Mitochondrial Proteins