title: Hg(2+) mediated quinazoline ensemble for highly selective recognition of Cysteine.
abstract: A fluorimetric sensor for Hg(2+) ion and Cysteine based on quinazoline platform was designed and synthesized by one step reaction and characterized by using common spectroscopic methods. Time Dependent Density Functional Theory calculations shows that probe behaves as "ON-OFF" fluorescent quenching sensor via electron transfer/heavy atom effect. Receptor was found to exhibit selective fluorescence quenching behavior over the other competitive metal ions, and also the receptor-Hg(2+) ensemble act as an efficient "OFF-ON" sensor for Cysteine. Moreover this sensor has also been successfully applied to detection of Hg(2+) in natural water samples with good recovery.
authors.affiliation: School of Chemistry, Madurai Kamaraj University, Madurai 625021, India.
authors.forename: Thangaraj
authors.initials: T
authors.lastname: Anand
authors.affiliation: School of Chemistry, Madurai Kamaraj University, Madurai 625021, India.
authors.forename: Gandhi
authors.initials: G
authors.lastname: Sivaraman
authors.affiliation: School of Chemistry, Madurai Kamaraj University, Madurai 625021, India. Electronic address: dcmku123@gmail.com.
authors.forename: Duraisamy
authors.initials: D
authors.lastname: Chellappa
mesh_terms: D002413:Cations, Divalent / Q000032:analysis; D003545:Cysteine / Q000032:analysis*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D057230:Limit of Detection; D008628:Mercury / Q000032:analysis*; D008958:Models, Molecular; D011799:Quinazolines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods; D014867:Water / Q000032:analysis
chemical_list: D002413:Cations, Divalent; D005456:Fluorescent Dyes; D011799:Quinazolines; D014867:Water; D008628:Mercury; D003545:Cysteine
keywords: Cysteine; Hg(2+); ON–OFF; Quenching; Quinazoline; Real sample analysis