title: [Impulse control disorders in Parkinson's disease].
abstract: Of the patients having Parkinson's disease, up to third encounters some degree of impulse control problems and one out of seven suffers from true impulse control disorders such as pathological gambling, hypersexuality, compulsive shopping and binge eating. Dopaminergic drugs used in anti-Parkinson therapy, especially dopamine agonists, increase the risk of these disorders. Impulse control disorders are associated with a relatively more active dopamine-mediated neurotransmission of the mesolimbic and mesocortical system. Discontinuation of dopamine agonist medication can thus be considered as the first line treatment of these disorders.
authors.affiliation: Satakunnan keskussairaala, neurologian klinikka, TYKS.
authors.forename: Juho
authors.initials: J
authors.lastname: Joutsa
authors.affiliation: TYKS ja Turun yliopisto, valtakunnallinen PET-keskus.
authors.forename: Valtteri
authors.initials: V
authors.lastname: Kaasinen
mesh_terms: D000978:Antiparkinson Agents / Q000009:adverse effects*; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000139:chemically induced*; D006801:Humans; D010300:Parkinson Disease / Q000188:drug therapy*
chemical_list: D000978:Antiparkinson Agents