title: The value of ultrasound elastography in differentiation of malignancy in thyroid nodules.
abstract: We aimed to determine the value of ultrasound elastography (US-E) using carotid artery pulsation in differentiation of malignant and benign thyroid nodules. One hundred ten nodules were evaluated by US-E, and stiffness scores were compared to biopsy results. When cutoff for malignancy was determined as score 4, sensitivity, specificity, positive predictive value, and negative predictive value were 100%, 95%, 40%, and 100%, respectively. We suggest fine needle aspiration biopsy to be performed in all score 4 nodules, while biopsy may be unnecessary in score 1 nodules. Benign biopsy result in a score 4 nodule should suggest radiological-pathological disagreement, and repeat biopsy should be recommended.
authors.affiliation: Department of Radiology, Sanliurfa Children's Hospital, Sanliurfa, Turkey.
authors.forename: Mehmet Arif
authors.initials: MA
authors.lastname: Akcay
authors.affiliation: Department of Radiology, Umraniye Training and Research Hospital, Istanbul, Turkey. Electronic address: asoysu@gmail.com.
authors.forename: Aslihan
authors.initials: A
authors.lastname: Semiz-Oysu
authors.affiliation: Department of Pathology, Marmara University Hospital, Istanbul, Turkey.
authors.forename: Rengin
authors.initials: R
authors.lastname: Ahiskali
authors.affiliation: Department of Radiology, Marmara University Hospital, Istanbul, Turkey.
authors.forename: Erkin
authors.initials: E
authors.lastname: Aribal
mesh_terms: D000328:Adult; D044963:Biopsy, Fine-Needle; D002339:Carotid Arteries / Q000473:pathology; D054459:Elasticity Imaging Techniques; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging*; D016606:Thyroid Nodule / Q000175:diagnosis / Q000000981:diagnostic imaging*; D014463:Ultrasonography / Q000379:methods*
keywords: Elastography; Fine needle aspiration biopsy; Nodule; Thyroid gland; Ultrasound