title: The race for regeneration: Pluripotent-stem-cell-derived 3D kidney structures.
abstract: The kidney's complex spatial organization and poorly defined lineage specification programs have impeded derivation of kidney progenitors from pluripotent stem cells (PSCs). Now in Cell Stem Cell, Taguchi et al. (2014) redefine the identity of embryonic kidney progenitors in vivo to obtain PSC-derived kidney progenitors that can form nephrons in vivo.
authors.affiliation: Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: valerie.gouon-evans@mssm.edu.
authors.forename: Valerie
authors.initials: V
authors.lastname: Gouon-Evans
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D053595:Embryonic Stem Cells / Q000166:cytology*; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology*; D007668:Kidney / Q000166:cytology*; D008648:Mesoderm / Q000166:cytology*; D009399:Nephrons / Q000166:cytology*; D038081:Organogenesis / Q000502:physiology*