title: New natural products as new leads for antibacterial drug discovery.
abstract: Natural products have been a rich source of antibacterial drugs for many decades, but investments in this area have declined over the past two decades. The purpose of this review article is to provide a recent survey of new natural product classes and the mechanisms by which they work.
authors.affiliation: AstraZeneca Pharmaceuticals, 35 Gatehouse Dr, Waltham, MA 02451, United States. Electronic address: dean.brown@astrazeneca.com.
authors.forename: Dean G
authors.initials: DG
authors.lastname: Brown
authors.affiliation: AstraZeneca Pharmaceuticals, 35 Gatehouse Dr, Waltham, MA 02451, United States.
authors.forename: Troy
authors.initials: T
authors.lastname: Lister
authors.affiliation: AstraZeneca Pharmaceuticals, 35 Gatehouse Dr, Waltham, MA 02451, United States.
authors.forename: Tricia L
authors.initials: TL
authors.lastname: May-Dracka
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry*; D018360:Crystallography, X-Ray; D055808:Drug Discovery / Q000379:methods / Q000639:trends*; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents; D001688:Biological Products
keywords: Antibacterial; Antimicrobial; Natural products