title: [Chemical constituents from roots and rhizomes of Panax ginseng cultivated in Jilin province].
abstract: The chemical constituents of the roots and rhizomes of Panax ginseng were systematically investigated by various column chromatographic methods including Amberlite XAD-4 macroporous adsorptive resins and silica gel as well as high-performance liquid chromatography, and their chemical structures were identified by physico-chemical properties and spectral analyses. Twenty-eight compounds were isolated from the 70% ethanolic-aqueous extract and identified as koryoginsenoside R1 (1), ginsenoside Rg1 (2), ginsenoside Rf (3), notoginsenoside R2 (4), ginsenoside Rg2 (5), notoginsenoside Fe (6), ginsenjilinol (7), ginsenoside Re5 (8), noto-ginsenoside N (9), notoginsenoside R1 (10), ginsenoside Re2 (11), ginsenoside Re1 (12), ginsenoside Re (13), ginsenoside Rs2 (14), ginsenoside Ro methyl ester (15), ginsenoside Rd (16), ginsenoside Re3 (17), ginsenoside Re4 (18), 20-gluco-ginsenoside Rf (19), ginsenoside Ro (20), ginsenoside Rc (21), quinquenoside-R1 (22), ginsenoside Ra2 (23), ginsenoside Rb1 (24), ginsenoside Ra1 (25), ginsenoside Ra3 (26), ginsenoside Rb2 (27), and notoginsenoside R4 (28). All isolated compounds are 20 (S) -protopanaxadiol or protopanaxatriol type triterpenoid saponins. Compound 1 was isolated from the roots and rhizomes of P. ginseng cultivated in Jilin province for the first time and compound 6 was isolated from the roots and rhizomes of P. ginseng for the first time. The 1H-NMR data of compounds 6, 14 and 19 were assigned for the first time.
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. sungirl9626@163.com
authors.forename: Hong-Ping
authors.initials: HP
authors.lastname: Wang
authors.affiliation: Xiyuan Hospital, China Academy of Chinese Sciences, Beijing 100091, China.
authors.forename: Xin-Bao
authors.initials: XB
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
authors.forename: Xiu-Wei
authors.initials: XW
authors.lastname: Yang
authors.affiliation: Xiyuan Hospital, China Academy of Chinese Sciences, Beijing 100091, China.
authors.forename: Jian-Xun
authors.initials: JX
authors.lastname: Liu
authors.affiliation: Institute of Special Wild Economic Animals and Plants Science, Chinese Academy of Agricultural Sciences, Changchun 130122, China.
authors.forename: Ying-Ping
authors.initials: YP
authors.lastname: Wang
authors.affiliation: College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
authors.forename: Lian-Xue
authors.initials: LX
authors.lastname: Zhang
mesh_terms: D002681:China; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D036145:Ginsenosides / Q000737:chemistry; D015394:Molecular Structure; D005894:Panax / Q000737:chemistry* / Q000254:growth & development; D018517:Plant Roots / Q000737:chemistry* / Q000254:growth & development; D012502:Sapogenins / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D004365:Drugs, Chinese Herbal; D036145:Ginsenosides; D012502:Sapogenins