title: Single-lobe living donor liver transplant in a morbidly obese cirrhotic patient preceded by laparoscopic sleeve gastrectomy.
abstract: Nonalcoholic steatohepatitis (NASH) is a stage of nonalcoholic fatty liver disease (NAFLD), and, in most patients, it is associated with obesity and metabolic syndrome with progression to end-stage liver disease in about 20% of patients (McCullough (2004); Matteoni et al. (1999); Liou and Kowdley (2006)). It has been estimated that between 20 and 30% of patients with end-stage cirrhosis referred for liver transplantation (LT) evaluation and 30 to 70% of LT recipients exhibit some degree of obesity (Muñoz and ElGenaidi (2005)). Management of obesity in chronic liver disease patients is not only difficult but also preludes them from undergoing major bariatric surgery due to associated high morbidity and mortality. Here, we present a case report of a morbidly obese patient who underwent laparoscopic sleeve gastrectomy followed by single-lobe living donor liver transplantation (LDLT) with a successful outcome. We believe that this is the first report of successful LDLT following planned weight loss to facilitate LDLT.
authors.affiliation: Department of Gastroenterology and Hepatology, Indraprastha Apollo Hospital, Delhi 110076, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Taneja
authors.affiliation: Department of Surgical Gastroenterology & Liver Transplantation, Centre for Liver & Biliary Surgery, Indraprastha Apollo Hospital, Delhi 110076, India.
authors.forename: Subash
authors.initials: S
authors.lastname: Gupta
authors.affiliation: Department of Gastroenterology and Hepatology, Indraprastha Apollo Hospital, Delhi 110076, India.
authors.forename: Manav
authors.initials: M
authors.lastname: Wadhawan
authors.affiliation: Department of Surgical Gastroenterology & Liver Transplantation, Centre for Liver & Biliary Surgery, Indraprastha Apollo Hospital, Delhi 110076, India.
authors.forename: Neerav
authors.initials: N
authors.lastname: Goyal