title: [Cognitive decline in elderly individuals with type 2 diabetes mellitus].
abstract: Cognitive decline in diabetes impairs the activity of daily living and shortens the healthy life expectancy. Once diabetes is accompanied by demented disorders, it becomes difficult to achieve good control of diabetes. Treatment for diabetes and demented disease should be provided concomitantly, because cognitive dysfunction worsens diabetic control and hyperglycemia worsens cognitive function vice versa, resulting in increased risks of acute metabolic failure. Compliance to medical treatment of diabetes is seriously impaired in the elderly with cognitive decline. Comprehensive approach with several medical specialists and care stuffs is thus needed. This manuscript briefly summaries the recent evidence for target of glycemic control and appropriate use of anti-diabetic medication in diabetic elderly with cognitive impairment.
authors.affiliation: Center for Comprehensive Care and Research on Memory Disorders, National Center for Geriatrics and Gerontology.
authors.forename: Takashi
authors.initials: T
authors.lastname: Sakurai
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000209:etiology*; D003191:Comprehensive Health Care; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000628:therapy*; D004359:Drug Therapy, Combination; D006801:Humans; D006943:Hyperglycemia / Q000150:complications / Q000628:therapy; D007004:Hypoglycemic Agents / Q000008:administration & dosage; D007328:Insulin / Q000008:administration & dosage; D007333:Insulin Resistance; D008019:Life Style; D010348:Patient Care Team; D012306:Risk; D012648:Self Care
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin