title: Unusual case of gastroparesis leading to severe gastromegaly with demyelinating disease as a rare cause.
abstract: BACKGROUND
  Gastroparesis is an entity of symptomatic abnormal gastric emptying, with diabetes mellitus, postsurgical and idiopathic etiologies accounting for majority of the cases.
  
  
  METHODS
  We report the case of a young African American female, who presented with abdominal discomfort, inability to tolerate a regular diet and intermittent episodes of numbness, tingling and cramps in her extremities. CT scan of the abdomen and pelvis showed a massively distended stomach, compressing the intestines and liver. A gastric emptying study revealing markedly worsened gastroparesis. Severe gastroparesis causing massive gastromegaly secondary to multiple sclerosis was diagnosed.
  
  
  CONCLUSIONS
  This case illustrates severe gastromegaly that is rarely seen to this extent and identifies multiple sclerosis (MS) as a rare cause of gastroparesis. MS should be considered in the differential diagnosis of gastroparesis in appropriate clinical settings.
authors.affiliation: Division of Internal Medicine, Sanford School of Medicine, the University of South Dakota, USA.
authors.forename: Kabir
authors.initials: K
authors.lastname: Ahmed
authors.affiliation: Division of Internal Medicine, Avera McKennan Hospital & University Health Center, USA.
authors.forename: Yasir
authors.initials: Y
authors.lastname: Lal
mesh_terms: D000328:Adult; D003711:Demyelinating Diseases / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D013271:Gastric Dilatation / Q000175:diagnosis / Q000209:etiology*; D005746:Gastric Emptying; D018589:Gastroparesis / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging