title: Evaluation of the degree of knee joint osteoarthritis in patients with early gray hair.
abstract: BACKGROUND
  Osteoarthritis (OA) is the most common form of arthritis and one of the causes of pain and disability. The hair graying characteristic correlates strictly with chronological aging and take places to varying degrees in all individuals, disregarding gender or race.
  
  
  OBJECTIVE
  Comparison of the degrees of clinical and radiologic severity of the knee OA in individuals with early hair graying compared to ordinary individuals.
  
  
  METHODS
  A total of 60 patients with knee OA and similar demographic characteristics were enrolled in this study. All patients were classified in to 3 age subgroups in each of the case and control groups (30-40 year, 41-50 year, 51-60 year). In the case group, the patients must had early hair graying, too. Knee OA were classified using the Kellgren-Lawrence (KL) grading scale. Western Ontario McMaster University Osteoarthritis index (WOMAC) was applied to assess clinical severity of the knee OA.
  
  
  RESULTS
  The mean ± SD of WOMAC index in the case group was 60.7 ± 15.9 and in the control group was 55.3 ± 15.3 (P = 0.1). The mean rank of KL scale in case group was 35.3 and in the control group was 25.6 (P = 0.02).
  
  
  CONCLUSIONS
  Even at the same age of OA onset, the rate of progression of radiological findings and the grade of joint destruction in individuals with early hair graying are greater than normal individuals. However, clinical and functional relevant remain unclear.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Behrooz
authors.initials: B
authors.lastname: Kazemi
authors.affiliation: Department of Physical Medicine and Rehabilitation, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran ; Department of Geriatric Research Center, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Ashraf
authors.affiliation: Department of Dermatology, Burn Research Center, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Namazi
authors.affiliation: Department of Radiology, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Fariba
authors.initials: F
authors.lastname: Zarei
authors.affiliation: Department of Physical Medicine and Rehabilitation, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Shima
authors.initials: S
authors.lastname: Foruzi
keywords: Early hair graying; knee; osteoarthritis