title: Cyclization-induced turn-on fluorescence system applicable to dicarboxylate sensing.
abstract: A novel tetraphenylethene-based fluorescence (FL) chemosensor exhibits nonlinear turn-on FL switching though cooperative binding of L-tartarate, where its convergent binding to form cyclic substructures is responsible for the FL increase. This binding scheme achieves selective detection of dicarboxylates over monocarboxylates, thus is potentially applicable to the preliminary screening for metabolic disorders.
authors.affiliation: Institute for Advanced Study, Kyushu University, 744 Moto-oka, Nishi-ku, Fukuoka 819-0395 (Japan); Nanotechnology Laboratory, Institute of Systems, Information Technologies and Nanotechnologies (ISIT), 4-1 Kyudai-Shinmachi, Nishi-ku, Fukuoka 819-0388 (Japan).
authors.forename: Takao
authors.initials: T
authors.lastname: Noguchi
authors.forename: Bappaditya
authors.initials: B
authors.lastname: Roy
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yoshihara
authors.forename: Youichi
authors.initials: Y
authors.lastname: Tsuchiya
authors.forename: Tatsuhiro
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Seiji
authors.initials: S
authors.lastname: Shinkai
mesh_terms: D000588:Amines / Q000737:chemistry*; D001555:Benzene Derivatives / Q000737:chemistry*; D056831:Coordination Complexes / Q000737:chemistry*; D003500:Cyclization; D005030:Ethylenes / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D010848:Picolinic Acids / Q000737:chemistry*; D013237:Stereoisomerism; D013644:Tartrates / Q000737:chemistry*; D014867:Water; D015032:Zinc
chemical_list: C501847:2,2'-dipicolylamine; D000588:Amines; D001555:Benzene Derivatives; D056831:Coordination Complexes; D005030:Ethylenes; D005456:Fluorescent Dyes; D010848:Picolinic Acids; D013644:Tartrates; D014867:Water; D015032:Zinc; C029768:tartaric acid
keywords: cooperativity; dicarboxylic acid; fluorescence; molecular recognition; nonlinear response