title: Analysis of kidney biopsy data from a single center in the midland rural area of china, 1996-2010.
abstract: OBJECTIVE
  To survey the clinical epidemiology and correlations between pathology and clinical features of major groups of kidney diseases in a rural area of China.
  
  
  METHODS
  From January 1996 to December 2010, histologic diagnosis of renal disease was made on samples collected from 919 patients from a single center in the midland rural area of China. Demographic data were obtained from all patients, and clinical profiles were analyzed in 917 patients.
  
  
  RESULTS
  The mean age of the whole group was 33.13 (14.13) years (range 16-72 years). Men accounted for 55.28% (n = 508) and women made up 45.72% (n = 408). Patients aged 16 to 50 years comprised 83.75% of the sample (n = 770). Lupus nephritis was the predominant diagnosis in women; renal diseases were predominant in men. In patients with nephrotic syndrome, mesangial proliferative glomerulonephritis was the most frequent pathologic pattern (39.46%), followed by IgA nephropathy (18.39%), whereas in patients with nephritic syndrome, IgA nephropathy (39.64%) was the most frequent pathologic pattern, followed by mesangial proliferative glomerulonephritis (32.38%). The most common pathologic pattern in patients with secondary glomerulonephritis was Henoch-Schoˇnlein purpura nephritis, followed by lupus nephritis.
  
  
  CONCLUSIONS
  Mesangial proliferative glomerulonephritis was the most common renal pathologic pattern. Male adolescents were predominant in this group of patients. The most common clinical syndrome was nephrotic syndrome.
authors.affiliation: Department of Nephrology, The First Affiliated Hospital, Xinxiang Medical University, Xinxiang, China.
authors.forename: Yong-Tao
authors.initials: YT
authors.lastname: Wang
authors.affiliation: Department of Life Science and Technology, Xinxiang Medical University, Xinxiang, China.
authors.forename: Chen-Yan
authors.initials: CY
authors.lastname: Zhou
authors.affiliation: Department of Nephrology, The First Affiliated Hospital, Xinxiang Medical University, Xinxiang, China.
authors.forename: Tie-Chui
authors.initials: TC
authors.lastname: Zhu
authors.affiliation: Department of Nephrology, The First Affiliated Hospital, Xinxiang Medical University, Xinxiang, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Nephrology, The First Affiliated Hospital, Xinxiang Medical University, Xinxiang, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Nephrology, The First Affiliated Hospital, Xinxiang Medical University, Xinxiang, China.
authors.forename: Qing-Yu
authors.initials: QY
authors.lastname: Xu
authors.affiliation: Department of Nephrology, The First Affiliated Hospital, Xinxiang Medical University, Xinxiang, China.
authors.forename: Ming-Hao
authors.initials: MH
authors.lastname: Guo
keywords: epidemiology; pathologic pattern; renal biopsy; rural