title: The J-curve relationship between diastolic pressure and coronary collateral circulation in patients with single chronic total occlusion.
abstract: BACKGROUND
  In our previous study, we had shown that high diastolic blood pressure (DBP) was positively related to well-developed coronary collateral circulation (CCC). This study sought to find out the more precise relationship between DBP and CCC.
  
  
  RESULTS
  To investigate this, we conducted a study of 671 patients with single chronic total occlusion of coronary artery. The DBP of the patients was divided into six groups: ≤ 65 mmHg, >65-≤ 75 mmHg, >75-≤ 85 mmHg, >85-≤ 95 mmHg, >95-≤ 105 mmHg, >105 mmHg). The extent of CCC was graded as poorly-developed or well-developed collaterals according to Rentrop classification. There was a J-curve relationship between the level of DBP and the incidence of poorly-developed collaterals.
  
  
  CONCLUSIONS
  The relationship between DBP and CCC is similar to the J-curve relationship between DBP and cardiovascular risk. The influence of DBP on the development of CCC may be one of the pathophysiologic mechanisms of the J-curve phenomenon relating DBP to cardiovascular risk.
authors.affiliation: The Cardiovascular Medical Department of the General Hospital of Chinese People of Liberation Army, Fu Xin Road Number 28, Beijing 100853, China.
authors.forename: Wang
authors.initials: W
authors.lastname: Shu
authors.affiliation: The Cardiovascular Medical Department of the General Hospital of Chinese People of Liberation Army, Fu Xin Road Number 28, Beijing 100853, China.
authors.forename: Wang Jin
authors.initials: WJ
authors.lastname: Da
authors.affiliation: The Cardiovascular Medical Department of the General Hospital of Chinese People of Liberation Army, Fu Xin Road Number 28, Beijing 100853, China.
authors.forename: Liu Chang
authors.initials: LC
authors.lastname: Fu
authors.affiliation: The Cardiovascular Medical Department of the General Hospital of Chinese People of Liberation Army, Fu Xin Road Number 28, Beijing 100853, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Jing
authors.affiliation: The Cardiovascular Medical Department of the General Hospital of Chinese People of Liberation Army, Fu Xin Road Number 28, Beijing 100853, China.
authors.forename: Guo
authors.initials: G
authors.lastname: Jun
authors.affiliation: The Cardiovascular Medical Department of the General Hospital of Chinese People of Liberation Army, Fu Xin Road Number 28, Beijing 100853, China.
authors.forename: Fu Zhen
authors.initials: FZ
authors.lastname: Hong
authors.affiliation: The Cardiovascular Medical Department of the General Hospital of Chinese People of Liberation Army, Fu Xin Road Number 28, Beijing 100853, China.
authors.forename: Jin Qin
authors.initials: JQ
authors.lastname: Hua
authors.affiliation: The Cardiovascular Medical Department of the General Hospital of Chinese People of Liberation Army, Fu Xin Road Number 28, Beijing 100853, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Lian
authors.affiliation: The Cardiovascular Medical Department of the General Hospital of Chinese People of Liberation Army, Fu Xin Road Number 28, Beijing 100853, China. Electronic address: chenyundai2002@163.com.
authors.forename: Chen Yun
authors.initials: CY
authors.lastname: Dai
mesh_terms: D000367:Age Factors; D000368:Aged; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000503:physiopathology*; D003097:Collateral Circulation / Q000502:physiology*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000503:physiopathology; D003326:Coronary Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D012307:Risk Factors
keywords: Coronary collateral circulation; Diastolic blood pressure; J-curve phenomenon