title: [A case of hepatocellular carcinoma (Vp4)-combination therapy prolonged survival in a patient with advanced hepatocellular carcinoma with a tumor thrombus in the portal vein trunk].
abstract: A 44-year-old man with advanced hepatocellular carcinoma (HCC) was admitted to our institution. Abdominal computed tomography( CT) revealed diffuse HCC in the right lobe, with a tumor thrombus in the main trunk and contralateral branch of the portal vein. Right lobectomy and tumor thrombectomy were performed. Three months later, oral tegafur-uraci( l UFT) administration( 300 mg/day) was initiated. Twelve months after surgery, intrahepatic recurrence was detected on CT scans. Therefore, the patient was treated with transcatheter arterial infusion( TAI) and percutaneous ethanol injection therapy (PEIT). Since then, no evidence of HCC recurrence has been noted for 46 months after the initial treatment.
authors.affiliation: Dept. of Surgery, Saiseikai Suita Hospital.
authors.forename: Sachio
authors.initials: S
authors.lastname: Terai
authors.forename: Kentaro
authors.initials: K
authors.lastname: Tai
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Kanbara
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000098:blood supply / Q000150:complications / Q000188:drug therapy* / Q000601:surgery; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000098:blood supply / Q000150:complications / Q000188:drug therapy* / Q000601:surgery; D008297:Male; D011169:Portal Vein; D005641:Tegafur / Q000008:administration & dosage; D013927:Thrombosis / Q000209:etiology* / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D005641:Tegafur; D005472:Fluorouracil