title: Resuscitation of a neonate with medium chain acyl-coenzyme a dehydrogenase deficiency using extracorporeal life support.
abstract: We report a neonate with medium chain acyl-coenzyme A dehydrogenase deficiency (MCAD) who had a cardiac arrest due to ventricular tachycardia and fibrillation. Extracorporeal life support (ECLS) was deployed, from which the baby was subsequently separated and discharged from hospital. This case was a rare neonatal presentation of MCAD and an uncommon indication for ECLS. We discuss the presentations of patients with MCAD and the use of ECLS for patients with possible inborn errors of metabolism and other unknown primary diagnoses.
authors.affiliation: Queensland Paediatric Cardiac Service, Mater Children's Hospital, Brisbane, Australia.
authors.forename: Gaurav
authors.initials: G
authors.lastname: Kumar
authors.forename: Adrian C
authors.initials: AC
authors.lastname: Mattke
authors.forename: Frank
authors.initials: F
authors.lastname: Bowling
authors.forename: Avis
authors.initials: A
authors.lastname: McWhinney
authors.forename: Nelson
authors.initials: N
authors.lastname: Alphonso
authors.forename: Tom R
authors.initials: TR
authors.lastname: Karl
mesh_terms: D042964:Acyl-CoA Dehydrogenase / Q000172:deficiency*; D016887:Cardiopulmonary Resuscitation; D002331:Carnitine / Q000627:therapeutic use; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods; D006323:Heart Arrest / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007231:Infant, Newborn; D008052:Lipid Metabolism, Inborn Errors / Q000150:complications / Q000628:therapy*; D008297:Male; D016896:Treatment Outcome; D014693:Ventricular Fibrillation / Q000150:complications; D014803:Vitamin B Complex / Q000627:therapeutic use
chemical_list: D014803:Vitamin B Complex; D042964:Acyl-CoA Dehydrogenase; D002331:Carnitine
keywords: extracorporeal life support; medium chain acyl-coenzyme A dehydrogenase deficiency; ventricular fibrillation