title: A case of mucosal leishmaniasis: Mimicking intranasal tumor with perforation of septum.
abstract: A 79-year-old male suffering from nasal congestion was referred to our hospital. Endoscopic examination revealed a hyperemic mass obstructing the left nasal passage. The lesion's surface was smooth. The findings of imaging studies were consistent with a benign tumor despite the erosion and perforation of the septum. The lesion originated from the middle concha and was attached to it with a thin stalk. It was removed easily by endoscopic resection. Histopathology revealed significant infiltration of mononuclear inflammatory cells, mostly lymphocytes and histiocytes, into the edematous subepithelial connective tissue. High-power magnification showed numerous Leishmania amastigotes in the cytoplasm of the histiocytes. A polymerase chain reaction experiment for Leishmania also confirmed the morphological diagnosis. No relapse was observed in the 12 months after surgery and the patient was doing well.
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Gulhane Military Medical Academy and School of Medicine, Etlik, Ankara, Turkey. Electronic address: hcgul@yahoo.com.
authors.forename: Hanefi Cem
authors.initials: HC
authors.lastname: Gul
authors.affiliation: Department of Otolaryngology, Gulhane Military Medical Academy and School of Medicine, Etlik, Ankara, Turkey.
authors.forename: Fuat
authors.initials: F
authors.lastname: Tosun
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Gulhane Military Medical Academy and School of Medicine, Etlik, Ankara, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Karakas
authors.affiliation: Department of Microbiology, Gulhane Military Medical Academy and School of Medicine, Etlik, Ankara, Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Koru
authors.affiliation: Department of Pathology, Gulhane Military Medical Academy and School of Medicine, Etlik, Ankara, Turkey.
authors.forename: Onder
authors.initials: O
authors.lastname: Onguru
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Gulhane Military Medical Academy and School of Medicine, Etlik, Ankara, Turkey.
authors.forename: Gurkan
authors.initials: G
authors.lastname: Mert
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Gulhane Military Medical Academy and School of Medicine, Etlik, Ankara, Turkey.
authors.forename: Bulent Ahmet
authors.initials: BA
authors.lastname: Besirbellioglu
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Gulhane Military Medical Academy and School of Medicine, Etlik, Ankara, Turkey.
authors.forename: Can Polat
authors.initials: CP
authors.lastname: Eyigun
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D006801:Humans; D007891:Leishmania / Q000302:isolation & purification; D007896:Leishmaniasis / Q000175:diagnosis* / Q000601:surgery*; D008297:Male; D015508:Nasal Obstruction / Q000175:diagnosis* / Q000601:surgery*; D061270:Nasal Septal Perforation / Q000175:diagnosis*; D009669:Nose Neoplasms / Q000175:diagnosis*; D016133:Polymerase Chain Reaction
keywords: Leishmania; Leishmaniasis; Mucosal involvement; Septal perforation; Turkey