title: Evaluation of nocturnal bladder capacity and nocturnal urine volume in nocturnal enuresis.
abstract: OBJECTIVE
  To investigate the diagnostic accuracies of maximum voided volume (MVV) and first morning urine osmolality and compare these with accuracies of nocturnal bladder capacity (NBC) and nocturnal urine volume, respectively, in children with nocturnal enuresis.
  
  
  METHODS
  A total of 70 children with nocturnal enuresis were assessed (mean age 7.1 ± 2.2 years). Baseline parameters were obtained by measuring MVV using a voiding diary, first morning urine osmolality on a wetting day, diaper weight by checking twice per night and first morning urine volume.
  
  
  RESULTS
  The proportions of small NBC and small MVV were 34.3% (24 cases) and 55.7% (39 cases), respectively. The proportions of low osmolality of first morning urine and nocturnal polyuria (NP) were 45.7% (32 cases) and 25.7% (18 cases), respectively. The sensitivity and specificity of small MVV for small NBC were 53.8% and 90.3%, respectively; the sensitivity and specificity of first morning urine osmolality for NP were 33.3% and 50.0%, respectively.
  
  
  CONCLUSIONS
  The diagnostic accuracies of MVV and urine osmolality for small NBC and NP were only modest to low.
authors.affiliation: Department of Urology, Soonchunhyang University, School of Medicine, 1174 Jung-1-dong, Wonmi-gu, Bucheon-si, Gyunggi-do 424-767, Republic of Korea. Electronic address: urojun@schmc.ac.kr.
authors.forename: Jun-Mo
authors.initials: JM
authors.lastname: Kim
authors.affiliation: Department of Medical Biotechnology, Soonchunhyang University, College of Medical Sciences, Asan, Republic of Korea.
authors.forename: Jae-Wook
authors.initials: JW
authors.lastname: Park
authors.affiliation: Department of Medical Biotechnology, Soonchunhyang University, College of Medical Sciences, Asan, Republic of Korea.
authors.forename: Chang-Seok
authors.initials: CS
authors.lastname: Lee
mesh_terms: D002648:Child; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D053158:Nocturia / Q000503:physiopathology* / Q000652:urine; D009994:Osmolar Concentration; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D016482:Urinalysis; D014554:Urination / Q000502:physiology*; D014563:Urodynamics / Q000502:physiology*
keywords: Nocturnal enuresis; Osmolar concentration; Urinary bladder