title: Systemic lupus erythematosus and human endogenous retroviruses.
abstract: Abstract  Human endogenous retroviruses (HERV) are known to be widely present in the human genome. Several investigations have suggested a possible etiological role of HERV in certain human disorders, including systemic lupus erythematosus (SLE). Here we review and discuss the possible role of HERV, especially HERV clone 4-1, in the onset of SLE, based on recent findings including our own data.
authors.affiliation: Department of Medicine, Juntendo University Izu-Nagaoka Hospital , 1129 Nagaoka, Izu-Nagaoka-cho, Tagata-gun, Shizuoka 410-2295 , Japan.
authors.forename: Iwao
authors.initials: I
authors.lastname: Sekigawa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ogasawara
authors.forename: Toshio
authors.initials: T
authors.lastname: Naito
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kaneko
authors.forename: Takashi
authors.initials: T
authors.lastname: Hishikawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hashimoto