title: COX-2 gene expression is correlated with cognitive function in recurrent depressive disorder.
abstract: Cyclooxygenase-2(COX-2) may be a key inflammatory enzyme involved in recurrent depressive disorder(rDD). In rDD group, COX-2 expression were higher and significant correlations occurred between COX-2 expression and cognitive functions. In controls there was no significant association between analysed variables. Thus, the COX-2 enzyme may be important for cognitive functioning in rDD.
authors.affiliation: Department of Adult Psychiatry, Medical University of Lodz, Aleksandrowska 159, 91-229 Lodz, Poland. Electronic address: galeckipiotr@wp.pl.
authors.forename: Piotr
authors.initials: P
authors.lastname: Gałecki
authors.affiliation: Department of Adult Psychiatry, Medical University of Lodz, Aleksandrowska 159, 91-229 Lodz, Poland.
authors.forename: Monika
authors.initials: M
authors.lastname: Talarowska
authors.affiliation: Department of Adult Psychiatry, Medical University of Lodz, Aleksandrowska 159, 91-229 Lodz, Poland.
authors.forename: Kinga
authors.initials: K
authors.lastname: Bobińska
authors.affiliation: Department of Medical Biochemistry, Medical University of Lodz, Lodz, Poland.
authors.forename: Janusz
authors.initials: J
authors.lastname: Szemraj
mesh_terms: D000328:Adult; D000368:Aged; D003071:Cognition; D051546:Cyclooxygenase 2 / Q000235:genetics*; D003866:Depressive Disorder / Q000235:genetics* / Q000523:psychology; D005260:Female; D015870:Gene Expression; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012008:Recurrence; D055815:Young Adult
chemical_list: D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human
keywords: COX-2; Cognition; Depression