title: Biomimetic polymer scaffolds to promote stem cell-mediated osteogenesis.
abstract: Bone tissue engineering using stem cells with osteogenic potential is a promising avenue of research for bone defect reconstruction. Organic, inorganic, and composite scaffolds have all been engineered to provide biomimetic microenvironments for stem cells. These scaffolds are designed to promote stem cell osteogenesis. Here, we review current technologies for developing biomimetic, osteoinductive scaffolds for stem cell applications. We summarize the reported in vitro and in vivo osteogenic effects of these scaffolds on stem cells.
authors.affiliation: Department of Biotechnology, Yonsei University, Seoul, Korea.
authors.forename: Eunkyung
authors.initials: E
authors.lastname: Ko
authors.affiliation: Department of Biotechnology, Yonsei University, Seoul, Korea.
authors.forename: Seung-Woo
authors.initials: SW
authors.lastname: Cho
keywords: Biomimetic scaffolds; Bone tissue engineering; Osteoinductivity; Stem cells