title: Genomic analysis of therapy-related acute promyelocytic leukemias arising after malignant and non-malignant disorders.
authors.affiliation: Department of Biopathology, University of Tor Vergata, Rome, Italy; Laboratorio di Neuro-Oncoematologia, Fondazione Santa Lucia, Rome, Italy.
authors.forename: Tiziana
authors.initials: T
authors.lastname: Ottone
authors.forename: Syed Khizer
authors.initials: SK
authors.lastname: Hasan
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Voso
authors.forename: Antonio
authors.initials: A
authors.lastname: Ledda
authors.forename: Enrico
authors.initials: E
authors.lastname: Montefusco
authors.forename: Susanna
authors.initials: S
authors.lastname: Fenu
authors.forename: Maria
authors.initials: M
authors.lastname: Pagoni
authors.forename: Maximillian
authors.initials: M
authors.lastname: Hubmann
authors.forename: Monia
authors.initials: M
authors.lastname: Lunghi
authors.forename: Uwe
authors.initials: U
authors.lastname: Platzbecker
authors.forename: Francesco
authors.initials: F
authors.lastname: Lo-Coco
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D056905:Chromosome Breakpoints; D002884:Chromosomes, Human, Pair 15 / Q000235:genetics* / Q000648:ultrastructure; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000209:etiology / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D008942:Mitoxantrone / Q000009:adverse effects / Q000627:therapeutic use; D009103:Multiple Sclerosis / Q000188:drug therapy; D009369:Neoplasms / Q000188:drug therapy; D016609:Neoplasms, Second Primary / Q000235:genetics*; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D020033:Protein Isoforms / Q000235:genetics; D059005:Topoisomerase II Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D014178:Translocation, Genetic / Q000235:genetics*
chemical_list: D000970:Antineoplastic Agents; D015514:Oncogene Proteins, Fusion; D020033:Protein Isoforms; D059005:Topoisomerase II Inhibitors; C093476:promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein; D008942:Mitoxantrone