title: Pulmonary echinococcal cyst with a filamentous fungus co-infection.
abstract: Fungal infections are known to colonize the pre-existing lung cavities formed as a result of diseases like tuberculosis, sarcoidosis, bronchiectasis and cavitatary neoplasia, mostly encountered in immunocompromised patients. Pulmonary echinococcal cysts have been reported coexistent with cryptococcosis and other saprophytic mycosis, but the coexistence of aspergillosis and echinococcal cyst is extremely rare and occasionally been reported in English literature. Active invasion and proliferation of the fungi in the laminated ectocyst of the echinococcal cyst is very unusual. We report a case of 60 years old immunocompetent female, presented with cough, chest pain and shortness of breath. The chest X-ray showed a large thick walled cavity in the lower and mid zone of right lung with positive water lily sign. Surgical enucleation of the echinococcal cyst revealed aspergilloma involving the cavity with massive invasion of laminated ectocyst by filamentous fungus, morphologically resembling an Aspergillus species and was further treated with Itraconazole for 3 months. This unique coexistence of active pulmonary echinococcosis and aspergillosis is being reported because of its rarity and clinical importance for its management.
authors.affiliation: Department of Pathology Maharishi Markandeshwar Institute of Medical Sciences and Research, M M University, Mullana, Ambala, Haryana, India.
authors.forename: P
authors.initials: P
authors.lastname: Pandey
authors.affiliation: Department of Pharmacology, Maharishi Markandeshwar Institute of Medical Sciences and Research, M M University, Mullana, Ambala, Haryana, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Dixit
authors.affiliation: Department of Pathology Maharishi Markandeshwar Institute of Medical Sciences and Research, M M University, Mullana, Ambala, Haryana, India.
authors.forename: A
authors.initials: A
authors.lastname: Tanwar
authors.affiliation: Department of Pathology Maharishi Markandeshwar Institute of Medical Sciences and Research, M M University, Mullana, Ambala, Haryana, India.
authors.forename: N C
authors.initials: NC
authors.lastname: Mahajan
mesh_terms: D001228:Aspergillosis / Q000150:complications* / Q000473:pathology; D060085:Coinfection / Q000000981:diagnostic imaging / Q000473:pathology; D004445:Echinococcosis, Pulmonary / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D011859:Radiography
keywords: Aspergillosis; echinococcal cyst; echinococcosis; mycosis; pulmonary