title: [Perioperative antibiotic prophylaxis].
abstract: In times of growing bacterial resistance against antimicrobiotic drugs the broad prescription of antibiotics in human medicine must be carefully considered. The perioperative antibiotic treatment is in the center of that conflict. On the one hand an efficient pathogen reduction for the preemptive treatment of infectious complications is desired but on the other hand it is suspected that this promotes the selection of multiresistant pathogens which could lead to an increase of more complicated nosocomial infections. The aim of this article is a critical appraisal of this subject on the basis of the 2012 guidelines of the German working group of Hygiene in Hospital and Practice (AWMF) and the 2010 recommendations of the Paul-Ehrlich-Gesellschaft.
authors.affiliation: Zentrum für Anästhesiologie und Intensivmedizin, Klinik und Poliklinik für Anästhesiologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
authors.forename: F
authors.initials: F
authors.lastname: Reutter
authors.forename: D A
authors.initials: DA
authors.lastname: Reuter
authors.forename: H
authors.initials: H
authors.lastname: Hilgarth
authors.forename: A M
authors.initials: AM
authors.lastname: Heilek
authors.forename: M S
authors.initials: MS
authors.lastname: Goepfert
authors.forename: M A
authors.initials: MA
authors.lastname: Punke
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis / Q000379:methods*; D001424:Bacterial Infections / Q000517:prevention & control; D003428:Cross Infection / Q000517:prevention & control; D005858:Germany; D017408:Guidelines as Topic; D006801:Humans; D019990:Perioperative Care / Q000379:methods*; D013530:Surgical Wound Infection / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents