title: Fulminant heterotopic ossification after combat-related amputation: a report of 2 cases.
abstract: Heterotopic ossification (HO) is the process of abnormal formation of lamellar bone in nonosseous tissues. In this case presentation, we describe patients with aggressive HO, which becomes symptomatic shortly after injury for which we have suggested the term "fulminant heterotopic ossification." These atypical presentations of fulminant HO highlight the necessity for continued research directed at improved understanding of HO and may suggest a role for early partial surgical excision as a definitive management strategy.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20889(∗). Electronic address: Edward.A.Dolomisiewicz.mil@health.mil.
authors.forename: Edward A
authors.initials: EA
authors.lastname: Dolomisiewicz
authors.affiliation: Department of Physical Medicine and Rehabilitation, Walter Reed National Military Medical Center, Bethesda, MD(†).
authors.forename: Matthew E
authors.initials: ME
authors.lastname: Miller
authors.affiliation: Department of Orthopaedics, Walter Reed National Military Medical Center, Bethesda, MD(‡).
authors.forename: Benjamin K
authors.initials: BK
authors.lastname: Potter
mesh_terms: D000328:Adult; D000672:Amputation Stumps / Q000000981:diagnostic imaging* / Q000601:surgery; D000673:Amputation, Traumatic / Q000150:complications*; D005500:Follow-Up Studies; D006801:Humans; D007869:Leg Injuries / Q000601:surgery*; D008297:Male; D008889:Military Personnel; D009999:Ossification, Heterotopic / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D011859:Radiography; D012086:Reoperation; D014857:Warfare; D055815:Young Adult