title: Stroke and thrombus formation appending to the MitraClip: what is the appropriate anticoagulation regimen?
abstract: Percutaneous mitral valve repair with the MitraClip system (Abbot Vascular, USA) is a promising technique for the non-surgical treatment of mitral regurgitation in special situations. The case is reported of a 72-year-old patient with history of atrial fibrillation and a severely impaired left ventricular function who underwent successful MitraClip implantation because of functional mitral regurgitation grade 3. The patient's post-interventional course was complicated three weeks later by a cardioembolic stroke due to thrombus formation on the MitraClip, despite receiving dual platelet therapy.
authors.affiliation: Department of Cardiology, Cardiovascular Hospital Bad Neustadt, Germany. Karsten.Hamm@kardiologie-bad-neustadt.de
authors.forename: Karsten
authors.initials: K
authors.lastname: Hamm
authors.affiliation: Department of Cardiology, Cardiovascular Hospital Bad Neustadt, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Barth
authors.affiliation: Department of Cardiac Surgery, Cardiovascular Hospital Bad Neustadt, Germany.
authors.forename: Anno
authors.initials: A
authors.lastname: Diegeler
authors.affiliation: Department of Cardiology, Cardiovascular Hospital Bad Neustadt, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Kerber
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D017548:Echocardiography, Transesophageal; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000601:surgery*; D011183:Postoperative Complications; D020521:Stroke / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control
chemical_list: D000925:Anticoagulants