title: Association of prostate volume with voiding impairment and deterioration in quality of life after prostate biopsy.
abstract: OBJECTIVE
  To evaluate how voiding function and quality of life (QoL) were affected by transrectal ultrasound-guided prostate biopsy with respect to prostatic size and to determine whether there is a size-bothersomeness relationship.
  
  
  METHODS
  Ninety-two patients who were candidates for prostate biopsy were included. Ten-core prostate biopsies were taken, and patients were followed up for 7 days. The international prostate symptom score, QoL, maximum urine flow rate (Q-max) and average urine flow rate, postvoid residual urine, and prostate volume (Vp) of the patients were recorded at baseline and on postbiopsy day 7. On receiver operating characteristics curve analysis, a Vp of 38.8 mL was found to be the best cutoff point for deterioration in QoL after biopsy. Then, patients were divided into 2 groups according to baseline Vp, as <38.8 mL and ≥38.8 mL, group 1 and 2, respectively. Baseline and postbiopsy values were compared.
  
  
  RESULTS
  One patient in group 1 and 5 in group 2 developed acute urinary retention after biopsy, but the difference was not significant (P >.05). Only Vp and Q-max of group 1 (P <.001 and P = .035, respectively), but QoL (P = .002), international prostate symptom score, Q-max, Vp (P <.001 in all 3), and average urine flow rate (P = .006) of group 2 were significantly changed on postbiopsy day 7 compared with baseline.
  
  
  CONCLUSIONS
  Patients with a Vp >38.8 mL were more prone to voiding difficulty and deterioration in QoL after biopsy. They should be informed about the likelihood of these complications.
authors.affiliation: Urology Clinic, Numune Training and Research Hospital, Ankara, Turkey. Electronic address: kaanaktas73@hotmail.com.
authors.forename: Binhan Kagan
authors.initials: BK
authors.lastname: Aktas
authors.affiliation: Urology Clinic, Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Suleyman
authors.initials: S
authors.lastname: Bulut
authors.affiliation: Urology Clinic, Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Cevdet Serkan
authors.initials: CS
authors.lastname: Gokkaya
authors.affiliation: Urology Clinic, Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Cuneyt
authors.initials: C
authors.lastname: Ozden
authors.affiliation: Urology Clinic, Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Remzi
authors.initials: R
authors.lastname: Salar
authors.affiliation: Urology Clinic, Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Yilmaz
authors.initials: Y
authors.lastname: Aslan
authors.affiliation: Urology Clinic, Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Mehmet Murat
authors.initials: MM
authors.lastname: Baykam
authors.affiliation: Department of Urology, School of Medicine, Kafkas University, Kars, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Memis
mesh_terms: D000368:Aged; D019540:Area Under Curve; D062005:Biopsy, Large-Core Needle / Q000009:adverse effects*; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology*; D011470:Prostatic Hyperplasia / Q000473:pathology; D011471:Prostatic Neoplasms / Q000473:pathology*; D011788:Quality of Life; D012372:ROC Curve; D011795:Surveys and Questionnaires; D018084:Ultrasonography, Interventional; D016055:Urinary Retention / Q000209:etiology*; D014563:Urodynamics