title: Prevalence of parent-reported immediate hypersensitivity food allergy in Chilean school-aged children.
abstract: BACKGROUND
  Food allergies (FAs) affect 2-4% of school-aged children in developed countries and strongly impact their quality of life. The prevalence of FA in Chile remains unknown.
  
  
  METHODS
  Cross-sectional survey study of 488 parents of school-aged children from Santiago who were asked to complete a FA screening questionnaire. Parents who reported symptoms suggestive of FA were contacted to answer a second in-depth questionnaire to determine immediate hypersensitivity FA prevalence and clinical characteristics of school-aged Chilean children.
  
  
  RESULTS
  A total of 455 parents answered the screening questionnaire: 13% reported recurrent symptoms to a particular food and 6% reported FA. Forty-three screening questionnaires (9%) were found to be suggestive of FA. Parents of 40 children answered the second questionnaire; 25 were considered by authors to have FA. FA rate was 5.5% (95% CI: 3.6-7.9). Foods reported to frequently cause FA included walnut, peanut, egg, chocolate, avocado, and banana. Children with FA had more asthma (20% vs. 7%, P<0.02) and atopic dermatitis (32% vs. 13%, P<0.01) by report. The parents of children with FA did not report anaphylaxis, but 48% had history compatible with anaphylaxis. Of 13 children who sought medical attention, 70% were diagnosed with FA; none were advised to acquire an epinephrine autoinjector.
  
  
  CONCLUSIONS
  Up to 5.5% of school-aged Chilean children may suffer from FA, most frequently to walnut and peanut. It is critical to raise awareness in Chile regarding FA and recognition of anaphylaxis, and promote epinephrine autoinjectors in affected children.
authors.affiliation: Allergy and Immunology Unit, Division of Pediatrics, School of Medicine, Pontificia Universidad Católica de Chile, Chile.
authors.forename: R
authors.initials: R
authors.lastname: Hoyos-Bachiloglu
authors.affiliation: Allergy and Immunology Unit, Division of Pediatrics, School of Medicine, Pontificia Universidad Católica de Chile, Chile.
authors.forename: D
authors.initials: D
authors.lastname: Ivanovic-Zuvic
authors.affiliation: Allergy and Immunology Unit, Division of Pediatrics, School of Medicine, Pontificia Universidad Católica de Chile, Chile.
authors.forename: J
authors.initials: J
authors.lastname: Álvarez
authors.affiliation: Allergy and Immunology Unit, Division of Pediatrics, School of Medicine, Pontificia Universidad Católica de Chile, Chile.
authors.forename: K
authors.initials: K
authors.lastname: Linn
authors.affiliation: Allergy and Immunology Unit, Division of Pediatrics, School of Medicine, Pontificia Universidad Católica de Chile, Chile.
authors.forename: N
authors.initials: N
authors.lastname: Thöne
authors.affiliation: Allergy and Immunology Unit, Division of Pediatrics, School of Medicine, Pontificia Universidad Católica de Chile, Chile.
authors.forename: M
authors.initials: M
authors.lastname: de los Ángeles Paul
authors.affiliation: Allergy and Immunology Unit, Division of Pediatrics, School of Medicine, Pontificia Universidad Católica de Chile, Chile; Millennium Institute on Immunology and Immunotherapy, School of Medicine, Pontificia Universidad Católica de Chile, Chile. Electronic address: arturobor@med.puc.cl.
authors.forename: A
authors.initials: A
authors.lastname: Borzutzky
mesh_terms: D000293:Adolescent; D000485:Allergens / Q000276:immunology; D000707:Anaphylaxis / Q000453:epidemiology / Q000209:etiology; D001249:Asthma / Q000453:epidemiology / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D002677:Chile; D003430:Cross-Sectional Studies; D003876:Dermatitis, Atopic / Q000453:epidemiology / Q000209:etiology; D005260:Female; D005512:Food Hypersensitivity / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D008297:Male; D010290:Parents; D015995:Prevalence; D057566:Self Report
chemical_list: D000485:Allergens
keywords: Anaphylaxis; Children; Chile; Epinephrine autoinjector; Food allergy; Immediate hypersensitivity; Parent-reported; Peanut allergy; Prevalence; Walnut allergy