title: Modulation of raft domains in a lipid bilayer by boundary-active curcumin.
abstract: The function and mode of action of curcumin in modulating the formation of lipid raft domains were investigated by microscopic observation using model membranes. Curcumin induces fusion of lipid raft domains at extremely low concentrations through the alteration of the boundary between the ordered and disordered phases.
authors.affiliation: Graduate School of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 6300192, Japan. yasuhara@ms.naist.jp.
authors.forename: Manami
authors.initials: M
authors.lastname: Tsukamoto
authors.forename: Kenichi
authors.initials: K
authors.lastname: Kuroda
authors.forename: Ayyalusamy
authors.initials: A
authors.lastname: Ramamoorthy
authors.forename: Kazuma
authors.initials: K
authors.lastname: Yasuhara
mesh_terms: D003474:Curcumin / Q000737:chemistry*; D008051:Lipid Bilayers; D021962:Membrane Microdomains
chemical_list: D008051:Lipid Bilayers; D003474:Curcumin