title: Potential for health screening using long-term cardiovascular parameters measured by finger volume-oscillometry: pilot comparative evaluation in regular and sleep-deprived activities.
abstract: We explored the potential of health screening based on the long-term measurement of cardiovascular parameters using the finger volume-oscillometric technique. An automated instrument made simultaneous measurements of key cardiovascular parameters, including blood pressure, pulse pressure, heart rate, normalized pulse volume as an index of α-adrenalin-mediated sympathetic activity, and finger arterial elasticity. These were derived from finger photo-plethysmographic signals during application of cuff pressure. To assess the feasibility of achieving a screening function, measurements were made in ten healthy volunteers during 10 days of day-to-day living (normal condition), and carried out several times at a fixed time every day. During successive 10-day measurements, a 30-hour period of total sleep deprivation was introduced as a physiological challenge (abnormal condition). A linear discriminant analysis of the data was conducted to determine whether these two conditions could be discriminated. Periodic data collection was performed rapidly and easily, and the %-correct classifications of normal and abnormal conditions were 78.2% and 77.5%, respectively. This ability of the method to discriminate between regular and sleep-deprived activities demonstrates its potential for healthcare screening during day-to-day living. Further investigations using larger age and gender groups of subjects including patients with cardiovascular diseases under real-life situations are required.
authors.forename: Takehiro
authors.initials: T
authors.lastname: Yamakoshi
authors.forename: Kenta
authors.initials: K
authors.lastname: Matsumura
authors.forename: Peter
authors.initials: P
authors.lastname: Rolfe
authors.forename: Shota
authors.initials: S
authors.lastname: Hanaki
authors.forename: Akira
authors.initials: A
authors.lastname: Ikarashi
authors.forename: Jihyoung
authors.initials: J
authors.lastname: Lee
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Yamakoshi
mesh_terms: D000328:Adult; D005385:Fingers / Q000098:blood supply* / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods*; D009991:Oscillometry / Q000379:methods*; D010865:Pilot Projects; D012892:Sleep Deprivation / Q000503:physiopathology*; D055815:Young Adult