title: Spectrophotometric analysis of phenols, which involves a hemin-graphene hybrid nanoparticles with peroxidase-like activity.
abstract: Phenols are well known noxious compounds, which are often found in various water sources. A novel analytical method has been researched and developed based on the properties of hemin-graphene hybrid nanosheets (H-GNs). These nanosheets were synthesized using a wet-chemical method, and they have peroxidase-like activity. Also, in the presence of H2O2, the nanosheets are efficient catalysts for the oxidation of the substrate, 4-aminoantipine (4-AP), and the phenols. The products of such an oxidation reaction are the colored quinone-imines (benzodiazepines). Importantly, these products enabled the differentiation of the three common phenols - pyrocatechol, resorcin and hydroquinone, with the use of a novel, spectroscopic method, which was developed for the simultaneous determination of the above three analytes. This spectroscopic method produced linear calibrations for the pyrocatechol (0.4-4.0 mg L(-1)), resorcin (0.2-2.0 mg L(-1)) and hydroquinone (0.8-8.0 mg L(-1)) analytes. In addition, kinetic and spectral data, obtained from the formation of the colored benzodiazepines, were used to establish multi-variate calibrations for the prediction of the three phenol analytes found in various kinds of water; partial least squares (PLS), principal component regression (PCR) and artificial neural network (ANN) models were used and the PLS model performed best.
authors.affiliation: State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China; Department of Chemistry, Nanchang University, Nanchang 330031, China.
authors.forename: Ruiling
authors.initials: R
authors.lastname: Sun
authors.affiliation: Department of Chemistry, Nanchang University, Nanchang 330031, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China; Department of Chemistry, Nanchang University, Nanchang 330031, China. Electronic address: ynni@ncu.edu.cn.
authors.forename: Yongnian
authors.initials: Y
authors.lastname: Ni
authors.affiliation: School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology, Brisbane 4001, Australia. Electronic address: s.kokot@qut.edu.au.
authors.forename: Serge
authors.initials: S
authors.lastname: Kokot
mesh_terms: D002396:Catechols / Q000032:analysis* / Q000737:chemistry; D060766:Drinking Water / Q000032:analysis; D006108:Graphite / Q000737:chemistry*; D006427:Hemin / Q000737:chemistry*; D006873:Hydroquinones / Q000032:analysis* / Q000737:chemistry; D060106:Lakes / Q000737:chemistry; D053761:Nanocomposites / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry; D010544:Peroxidases; D012118:Resorcinols / Q000032:analysis* / Q000737:chemistry; D013053:Spectrophotometry; D062065:Wastewater / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000737:chemistry
chemical_list: D002396:Catechols; D060766:Drinking Water; D006108:Graphite; D006427:Hemin; D006873:Hydroquinones; D010544:Peroxidases; D012118:Resorcinols; D062065:Wastewater; D014874:Water Pollutants, Chemical; C034221:catechol; C031927:hydroquinone; C031389:resorcinol
keywords: Benzodiazepines; Graphene; Hemin; Phenols; Spectrophotometry