title: Selective monomethylation of primary amines with simple electrophiles.
abstract: Direct monomethylation of primary amines with methyl triflate was achieved with high selectivity (up to 96%). The key point of this single methyl transfer stems from the use of HFIP as the solvent that interferes with amines and avoids overmethylation.
authors.affiliation: Normandie Univ, COBRA UMR 6014, Univ Rouen, INSA Rouen and CNRS, 1 rue Lucien Tesnière, 76821 Mont-Saint-Aignan, France. julien.legros@univ-rouen.fr.
authors.forename: Thomas
authors.initials: T
authors.lastname: Lebleu
authors.forename: Xiaolu
authors.initials: X
authors.lastname: Ma
authors.forename: Jacques
authors.initials: J
authors.lastname: Maddaluno
authors.forename: Julien
authors.initials: J
authors.lastname: Legros