title: [Borrelial lymphocytoma].
abstract: BACKGROUND
  Borrelial lymphocytoma is a relatively rare but typical presentation of Lyme disease. Predilection sites are the ears in children and chest/nipples in adults. It is treated like an erythema migrans and has a good prognosis.
  
  
  METHODS
  A 16-year-old boy presented with a swollen, red and painful right nipple since several months. An ultrasound showed normal breast tissue. The patient was referred to the pediatric surgeon who performed an incision biopsy. Histopathological examination revealed follicular hyperplasia without signs of malignancy. An infectious cause, most likely Lyme disease, was suspected. Serological analysis and PCR of the tissue confirmed the diagnosis of a borrelial lymphocytoma, and the patient was treated with doxycycline with good result.
  
  
  CONCLUSIONS
  Early recognition of the characteristic clinical presentation of borrelial lymphocytoma, supported by positive results from serologic testing for Lyme disease, avoids the need for additional and invasive diagnostic tests.
authors.affiliation: Radboudumc, Nijmegen.
authors.forename: Ellen J H
authors.initials: EJ
authors.lastname: Schatorjé
authors.forename: Herjan
authors.initials: H
authors.lastname: van der Steeg
authors.forename: Foekje
authors.initials: F
authors.lastname: Stelma
authors.forename: Konnie
authors.initials: K
authors.lastname: Hebeda
authors.forename: Adilia
authors.initials: A
authors.lastname: Warris
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001706:Biopsy; D003937:Diagnosis, Differential; D004318:Doxycycline / Q000627:therapeutic use; D015787:Erythema Chronicum Migrans / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D009558:Nipples / Q000473:pathology; D019310:Pseudolymphoma / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D004318:Doxycycline