title: Guillain-Barré syndrome following herpes zoster in a patient with systemic sclerosis.
abstract: Abstract We report the case of a patient with systemic sclerosis (SSc) who developed Guillain-Barré syndrome (GBS) 6 weeks after herpes zoster. Muscle weakness developed first, and thereafter severely in the muscles in the same segment as the zoster. Serum anti-GM1 and -GD1b IgM autoantibodies were detected in the acute phase. The clinical course and the findings of nerve conduction studies and a sural nerve biopsy were compatible with GBS accompanied by underlying chronic polyneuropathy. SSc might have affected the neurological manifestation via the development of underlying neuropathy and a possible contribution to the autoimmune basis in GBS.
authors.affiliation: Department of Medicine and Physical Therapy, University of Tokyo School of Medicine , 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 , Japan.
authors.forename: M
authors.initials: M
authors.lastname: Yamaguchi
authors.forename: A
authors.initials: A
authors.lastname: Chiba
authors.forename: T
authors.initials: T
authors.lastname: Yanagawa
authors.forename: T
authors.initials: T
authors.lastname: Mato
authors.forename: K
authors.initials: K
authors.lastname: Hirai
authors.forename: T
authors.initials: T
authors.lastname: Inoue
authors.forename: Y
authors.initials: Y
authors.lastname: Oya
authors.forename: S
authors.initials: S
authors.lastname: Kusunoki
authors.forename: K
authors.initials: K
authors.lastname: Ito
authors.forename: K
authors.initials: K
authors.lastname: Yamamoto