title: Central venous catheter-related infections in hematology and oncology: 2012 updated guidelines on diagnosis, management and prevention by the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology.
abstract: BACKGROUND
  Cancer patients are at increased risk for central venous catheter-related infections (CRIs). Thus, a comprehensive, practical and evidence-based guideline on CRI in patients with malignancies is warranted.
  
  
  METHODS
  A panel of experts by the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) has developed a guideline on CRI in cancer patients. Literature searches of the PubMed, Medline and Cochrane databases were carried out and consensus discussions were held.
  
  
  RESULTS
  Recommendations on diagnosis, management and prevention of CRI in cancer patients are made, and the strength of the recommendation and the level of evidence are presented.
  
  
  CONCLUSIONS
  This guideline is an evidence-based approach to the diagnosis, management and prevention of CRI in cancer patients.
authors.affiliation: Department of Hematology, Oncology and Palliative Care, Harlaching Hospital and Neuperlach Hospital, Munich.
authors.forename: M
authors.initials: M
authors.lastname: Hentrich
authors.forename: E
authors.initials: E
authors.lastname: Schalk
authors.forename: M
authors.initials: M
authors.lastname: Schmidt-Hieber
authors.forename: I
authors.initials: I
authors.lastname: Chaberny
authors.forename: S
authors.initials: S
authors.lastname: Mousset
authors.forename: D
authors.initials: D
authors.lastname: Buchheidt
authors.forename: M
authors.initials: M
authors.lastname: Ruhnke
authors.forename: O
authors.initials: O
authors.lastname: Penack
authors.forename: H
authors.initials: H
authors.lastname: Salwender
authors.forename: H-H
authors.initials: HH
authors.lastname: Wolf
authors.forename: M
authors.initials: M
authors.lastname: Christopeit
authors.forename: S
authors.initials: S
authors.lastname: Neumann
authors.forename: G
authors.initials: G
authors.lastname: Maschmeyer
authors.forename: M
authors.initials: M
authors.lastname: Karthaus
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000175:diagnosis* / Q000188:drug therapy / Q000517:prevention & control; D055499:Catheter-Related Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000517:prevention & control; D002404:Catheterization / Q000379:methods; D062905:Central Venous Catheters / Q000382:microbiology; D019468:Disease Management; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000517:prevention & control; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000517:prevention & control; D006405:Hematology; D006801:Humans; D008495:Medical Oncology
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents
keywords: catheter infection; central venous catheter; guidelines; neutropenia