title: [A case of early gastric cancer responding to adjuvant chemotherapy for treatment of colon cancer].
abstract: A 63-year-old man underwent colonoscopy owing to a positive fecal occult blood test, and he was diagnosed as having advanced sigmoid colon cancer. Esophagogastroduodenoscopy( EGD), performed as a preoperative examination, revealed an 8 mm early gastric cancer in the lower body of his stomach. We performed laparoscopic sigmoid colon resection and D3 lymphadenectomy first because the patient had advanced sigmoid colon cancer. The histopathological diagnosis was Stage II; however, vascular invasion was apparent. Some authors have reported that chemotherapy with 5-fluorouracil (FU) is effective against early gastric cancer; therefore, we administered postoperative adjuvant chemotherapy comprising uracil and tegafur( UFT)+Leucovorin( LV) tablets before ESD for early gastric cancer. Two months later, follow-up EGD showed that the gastric cancer had become flat and small. Five months later, it resembled a scar, and examination of a biopsy showed no malignant finding. We continued to administer chemotherapy to the patient for 6 months. Nine months after the discontinuation of chemotherapy, EGD showed only a scar and biopsy revealed no malignant finding.
authors.affiliation: Dept. of Surgery, Totsuka Kyouritsu Daiichi Hospital.
authors.forename: Akira
authors.initials: A
authors.lastname: Saito
authors.forename: Masahiko
authors.initials: M
authors.lastname: Murakami
authors.forename: Satoshi
authors.initials: S
authors.lastname: Suzuki
authors.forename: Masahiro
authors.initials: M
authors.lastname: Sagane
authors.forename: Takahiro
authors.initials: T
authors.lastname: Hayashi
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Enosawa
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Murai
authors.forename: Hiroto
authors.initials: H
authors.lastname: Yoshizawa
authors.forename: Kou
authors.initials: K
authors.lastname: Mochizuki
authors.forename: Motohiko
authors.initials: M
authors.lastname: Fukushima
authors.forename: Hideo
authors.initials: H
authors.lastname: Yokokawa
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy*; D012811:Sigmoid Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology