title: Exploring Potential Chemical Transformation by Chemical Profiling Approach for Rapidly Evaluating Chemical Consistency between Sun-Dried and Sulfur-Fumigated Radix Paeoniae Alba Using Ultraperformance Liquid Chromatography Coupled with Time-of-Flight Mass Spectrometry.
abstract: Ultraperformance liquid chromatography coupled with time-of-flight mass spectrometry (UPLC-QTOF/MS) based on a chemical profiling method was applied to rapidly evaluate the chemical consistency between sun-dried and sulfur-fumigated Radix Paeoniae Alba. By virtue of the high resolution, high speed of UPLC, and the accurate mass measurement of TOFMS coupled with reliable MarkerLynx software, five newly assigned monoterpene glycoside sulfonates were found and identified in sulfur-fumigated Radix Paeoniae Alba samples. This method could be applied for rapid quality evaluation of different kinds of sulfur-fumigated Radix Paeoniae Alba among commercial samples.
authors.affiliation: College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
authors.forename: Jida
authors.initials: J
authors.lastname: Zhang
authors.affiliation: College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Cai
authors.affiliation: College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China ; Research Center of TCM Processing Technology, Zhejiang Chinese Medical University, Hangzhou 310053, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Cao
authors.affiliation: College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Liu
authors.affiliation: College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
authors.forename: Chengping
authors.initials: C
authors.lastname: Wen
authors.affiliation: College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
authors.forename: Yongsheng
authors.initials: Y
authors.lastname: Fan