title: Recent advances in capillary electrophoretic migration techniques for pharmaceutical analysis.
abstract: Since the introduction about 30 years ago, CE techniques have gained a significant impact in pharmaceutical analysis. The present review covers recent advances and applications of CE for the analysis of pharmaceuticals. Both small molecules and biomolecules such as proteins are considered. The applications range from the determination of drug-related substances to the analysis of counterions and the determination of physicochemical parameters. Furthermore, general considerations of CE methods in pharmaceutical analysis are described.
authors.affiliation: Drug Analysis and Research Center, Department of Pharmaceutical Chemistry, Al-Azhar University - Gaza, Gaza, Palestine; Institute of Medicinal and Pharmaceutical Chemistry, TU Braunschweig, Braunschweig, Germany.
authors.forename: Sami El
authors.initials: SE
authors.lastname: Deeb
authors.forename: Hermann
authors.initials: H
authors.lastname: Wätzig
authors.forename: Deia Abd
authors.initials: DA
authors.lastname: El-Hady
authors.forename: Hassan M
authors.initials: HM
authors.lastname: Albishri
authors.forename: Cari Sänger-van
authors.initials: CS
authors.lastname: de Griend
authors.forename: Gerhard K E
authors.initials: GK
authors.lastname: Scriba
mesh_terms: D000911:Antibodies, Monoclonal / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D019075:Electrophoresis, Capillary; D007136:Immunoglobulins / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D004364:Pharmaceutical Preparations / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D011994:Recombinant Proteins / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D000911:Antibodies, Monoclonal; D007136:Immunoglobulins; D004364:Pharmaceutical Preparations; D011994:Recombinant Proteins
keywords: Biopharmaceuticals; CE; Pharmaceutical analysis; Quantitation