title: Effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification.
abstract: OBJECTIVE
  To evaluate the effect of brinzolamide-timolol fixed combination on intraocular pressure (IOP) after cataract surgery.
  
  
  METHODS
  The study included 92 eyes of 87 patients who underwent cataract surgery and intraocular lens implantation. Patients scheduled for phacoemulsification were assigned to 1 of 2 groups. The treatment group received 1 drop of brinzolamide-timolol fixed combination immediately after surgery, and the control group received no treatment. The IOP was measured preoperatively and at 2h and 24h postoperatively.
  
  
  RESULTS
  The mean IOP change was lower in the treatment group than in the control group at 2h postoperatively. The difference between the mean IOP values of the two groups at 2h postoperatively was found to be statistically significant. Twenty-four hours after the surgery, the mean IOP change was still higher in the control group when compared to the treatment group.
  
  
  CONCLUSIONS
  The fixed combination brinzolamide-timolol can effectively reduce IOP after cataract surgery.
authors.affiliation: Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.
authors.forename: Kemal
authors.initials: K
authors.lastname: Ornek
authors.affiliation: Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.
authors.forename: Nesrin
authors.initials: N
authors.lastname: Büyüktortop
authors.affiliation: Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.
authors.forename: Nurgül
authors.initials: N
authors.lastname: Ornek
authors.affiliation: Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.
authors.forename: Reyhan
authors.initials: R
authors.lastname: Oğurel
authors.affiliation: Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.
authors.forename: Inci Elif
authors.initials: IE
authors.lastname: Erbahçeci
authors.affiliation: Department of Ophthalmology, School of Medicine, Kırıkkale University, Kırıkkale 71100, Turkey.
authors.forename: Zafer
authors.initials: Z
authors.lastname: Onaran
keywords: brinzolamide; cataract surgery; timolol