title: Rare refractory Kawasaki disease in an adolescent boy with cardiac and diffuse coronary artery involvement.
abstract: Kawasaki disease is an acute multisystemic vasculitis occurring predominantly in infants and young children and rarely in adolescents and adults. At elderly age, Kawasaki disease may remain unrecognized with a subsequent delay in appropriate therapy and an increased risk of coronary artery aneurysms. We report a case of intravenous immunoglobulin- and aspirin-resistant Kawasaki disease and severe cardiovascular damage in an adolescent boy. The article discusses major issues associated with the management of refractory Kawasaki disease.
authors.affiliation: Department of Children Diseases, Medical Academy, Lithuanian University of Health Scien-ces, Eivenių 2, 50161 Kaunas, Lithuania. rima.sileikiene@kaunoklinikos.lt.
authors.forename: Rima
authors.initials: R
authors.lastname: Šileikienė
authors.forename: Jolanta
authors.initials: J
authors.lastname: Kudzytė
authors.forename: Antanas
authors.initials: A
authors.lastname: Jankauskas
authors.forename: Liutauras
authors.initials: L
authors.lastname: Labanauskas
authors.forename: Vilma
authors.initials: V
authors.lastname: Rakauskienė
authors.forename: Nemira
authors.initials: N
authors.lastname: Jurkienė
authors.forename: Rimantas
authors.initials: R
authors.lastname: Kėvalas
mesh_terms: D000293:Adolescent; D000925:Anticoagulants / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D003323:Coronary Aneurysm / Q000175:diagnosis* / Q000209:etiology; D004351:Drug Resistance; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D035583:Rare Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D016756:Immunoglobulins, Intravenous; D014859:Warfarin; D001241:Aspirin