title: Multiple metastases of malignant melanoma in the head and neck: a case report and literature review.
abstract: Malignant melanoma (MM) with multiple metastases (including the oral mucosa) is an extremely rare condition that is difficult to manage due to its complexity. This article presents the case of a 27-year-old man who first developed MM on the scalp, which subsequently metastasized to the mandible, parotid gland, infratemporal fossa, and the cervical regions of the larynx, kidneys, liver, and lungs. The findings of the present case report are compared with 31 other cases published in the English literature. Multiple metastases of MMs in the head and neck region are rare and generally are associated with a poor prognosis. In such cases, dentists play a role in the diagnosis, prevention, and treatment of sequelae stemming from oncologic treatment, with the aim of improving the patient's quality of life.
authors.forename: Fernanda Hack
authors.initials: FH
authors.lastname: Coehlo
authors.forename: Ana Carolina Amorim
authors.initials: AC
authors.lastname: Pellicioli
authors.forename: Marco Antonio Trevizani
authors.initials: MA
authors.lastname: Martins
authors.forename: Vanessa Christina Santos
authors.initials: VC
authors.lastname: Pavesi
authors.forename: Rafael Aron
authors.initials: RA
authors.lastname: Schmerling
authors.forename: Manoela Domingues
authors.initials: MD
authors.lastname: Martins
mesh_terms: D000328:Adult; D017809:Fatal Outcome; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D007680:Kidney Neoplasms / Q000556:secondary; D007822:Laryngeal Neoplasms / Q000556:secondary; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008339:Mandibular Neoplasms / Q000556:secondary; D008545:Melanoma / Q000473:pathology*; D010307:Parotid Neoplasms / Q000556:secondary; D012535:Scalp / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*
keywords: head and neck cancer; malignant melanoma; oral cavity; oral metastasis