title: Comparison of immediate and 2-year outcomes between excimer laser-assisted angioplasty with spot stent and primary stenting in intermediate to long femoropopliteal disease.
abstract: BACKGROUND
  To compare the clinical outcomes between excimer laser-assisted angioplasty (ELA) with spot stent (group A) and primary stenting (group B) in intermediate to long femoropopliteal disease.
  
  
  METHODS
  Outcomes of 105 patients totaling 119 legs treated with two different strategies were analyzed retrospectively in a prospectively maintained database.
  
  
  RESULTS
  Baseline characteristics were similar in both groups. Better angiographic results and lesser increase of serum C-reactive protein levels (0.60 ± 0.72 versus 2.98 ± 0.97 mg/dL, P < 0.001) after the intervention were obtained in Group B. Group A had inferior 1-year outcomes due to higher rate of binary restenosis (67% versus 32%, P = 0.001) and lower rate of primary patency (40% versus 58%, P = 0.039). Rates of amputation-free survival, target vessel revascularization, assisted primary patency, and stent fracture at 24 months were similar in both groups (80% versus 82%, P = 0.979, 65% versus 45%, P = 0.11, 78% versus 80%, P = 0.75 and 6.3% versus 6.8%, P = 0.71, resp.).
  
  
  CONCLUSIONS
  Greater vascular inflammation after ELA with spot stent resulted in earlier restenosis and inferior 1-year clinical outcomes than primary stenting. This benefit was lost in the primary stenting group at 2 years due to late catch-up restenosis. Active surveillance with prompt intervention was required to maintain the vessel patency.
authors.affiliation: Section of Cardiology, Department of Medicine, Taipei Tzu Chi Hospital, The Buddhist Tzu Chi Medical Foundation, 289 Jiang Kuo Road, Xindian District, New Taipei City 231, Taiwan.
authors.forename: Tien-Yu
authors.initials: TY
authors.lastname: Wu
authors.affiliation: Section of Cardiology, Department of Medicine, Taipei Tzu Chi Hospital, The Buddhist Tzu Chi Medical Foundation, 289 Jiang Kuo Road, Xindian District, New Taipei City 231, Taiwan.
authors.forename: Hsin-Hua
authors.initials: HH
authors.lastname: Chou
authors.affiliation: Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, 5 Fusing Street, Gueishan Township, Taoyuan County 333, Taiwan.
authors.forename: Shang-Hung
authors.initials: SH
authors.lastname: Chang
authors.affiliation: Department of Ophthalmology, Chang Gung Memorial Hospital, 5 Fusing Street, Gueishan Township, Taoyuan County 333, Taiwan.
authors.forename: Yueh-Ju
authors.initials: YJ
authors.lastname: Tsai
authors.affiliation: Section of Cardiology, Department of Medicine, Taipei Tzu Chi Hospital, The Buddhist Tzu Chi Medical Foundation, 289 Jiang Kuo Road, Xindian District, New Taipei City 231, Taiwan.
authors.forename: Chien-An
authors.initials: CA
authors.lastname: Hsieh
authors.affiliation: Section of Cardiology, Department of Medicine, Taipei Tzu Chi Hospital, The Buddhist Tzu Chi Medical Foundation, 289 Jiang Kuo Road, Xindian District, New Taipei City 231, Taiwan.
authors.forename: Shih-Tsung
authors.initials: ST
authors.lastname: Cheng
authors.affiliation: Section of Cardiology, Department of Medicine, Taipei Tzu Chi Hospital, The Buddhist Tzu Chi Medical Foundation, 289 Jiang Kuo Road, Xindian District, New Taipei City 231, Taiwan.
authors.forename: Kuan-Hung
authors.initials: KH
authors.lastname: Yeh
authors.affiliation: Section of Cardiology, Department of Medicine, Taipei Tzu Chi Hospital, The Buddhist Tzu Chi Medical Foundation, 289 Jiang Kuo Road, Xindian District, New Taipei City 231, Taiwan.
authors.forename: Hern-Jia
authors.initials: HJ
authors.lastname: Chang
authors.affiliation: Section of Cardiology, Department of Medicine, Taipei Tzu Chi Hospital, The Buddhist Tzu Chi Medical Foundation, 289 Jiang Kuo Road, Xindian District, New Taipei City 231, Taiwan.
authors.forename: Yu-Lin
authors.initials: YL
authors.lastname: Ko
authors.affiliation: Section of Cardiology, Department of Medicine, Taipei Tzu Chi Hospital, The Buddhist Tzu Chi Medical Foundation, 289 Jiang Kuo Road, Xindian District, New Taipei City 231, Taiwan.
authors.forename: Hsuan-Li
authors.initials: HL
authors.lastname: Huang
mesh_terms: D000368:Aged; D002097:C-Reactive Protein / Q000032:analysis; D023903:Coronary Restenosis / Q000209:etiology; D005260:Female; D005263:Femoral Artery / Q000503:physiopathology; D005500:Follow-Up Studies; D006801:Humans; D007866:Leg / Q000503:physiopathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000401:mortality / Q000601:surgery*; D011150:Popliteal Artery / Q000503:physiopathology; D015607:Stents; D016896:Treatment Outcome; D014654:Vascular Patency
chemical_list: D002097:C-Reactive Protein