title: Progressive dyspnea in patient with large mediastinal mass.
abstract: Liposarcoma occurs very rarely in the mediastinum. Patients often remain asymptomatic until it grows large enough to cause direct invasion or compression of adjacent organs. We report a case of a 77-year-old male presented with dyspnea of exertion and was found to have a large mediastinal mass which was eventually diagnosed as primary mediastinal well-differentiated liposarcoma. The limited respiratory function at the initial presentation prompted phrenic nerve preserving incomplete resection rather than radical removal of the adjacent mediastinal structures. After surgical removal, the recurrence for well-differentiated mediastinal liposarcomas in the mediastinum is unknown; therefore, close follow-up is crucial.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Fukuhara
authors.forename: Kamellia R
authors.initials: KR
authors.lastname: Dimitrova
authors.forename: Charles M
authors.initials: CM
authors.lastname: Geller
authors.forename: Darryl M
authors.initials: DM
authors.lastname: Hoffman
authors.forename: Wilson
authors.initials: W
authors.lastname: Ko
authors.affiliation: Division of Cardiac Surgery, Beth Israel Medical Center, 317 East 17th Street, 11th Floor, New York, NY 10003, USA. RTranbau@chpnet.org.
authors.forename: Robert F
authors.initials: RF
authors.lastname: Tranbaugh
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D018450:Disease Progression; D004417:Dyspnea / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008080:Liposarcoma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D013902:Radiography, Thoracic; D012720:Severity of Illness Index; D056346:Sternotomy / Q000379:methods; D014057:Tomography, X-Ray Computed