title: [Long-term survival of a patient with extrahepatic cholangiocarcinoma treated with adjuvant radiotherapy for positive ductal margins after surgical resection].
abstract: A 57-year-old man with abdominal discomfort visited our hospital. Abdominal computed tomography (CT) revealed no tumorous lesions. Endoscopic retrograde cholangiography (ERC) revealed a tumorous lesion in the middle bile duct. Peroral cholangioscopy-assisted biopsy was performed, and the lesion was diagnosed as a papillary adenocarcinoma. Extra bile duct resection and regional lymph node dissection were performed; however, residual carcinoma in situ was detected at the ductal margins by intraoperative frozen section analysis. Therefore, external radiation therapy at a dose 50.4 Gy/28 Fr was administered after the operation. No complication due to radiotherapy occurred. The patient remains alive and recurrence -free for more than 7 years after the operation. We report the long-term disease-free survival of a patient with extrahepatic cholangiocarcinoma who was treated with external radiation therapy for positive ductal margins after surgical resection.
authors.affiliation: Dept. of Gastroenterological Surgery, Takatsuki General Hospital.
authors.forename: Takuro
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Yu
authors.initials: Y
authors.lastname: Asakura
authors.forename: Nobuhide
authors.initials: N
authors.lastname: Higashino
authors.forename: Akira
authors.initials: A
authors.lastname: Arimoto
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Hosono
authors.forename: Nozomi
authors.initials: N
authors.lastname: Ueno
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Ienaga
authors.forename: Saeko
authors.initials: S
authors.lastname: Hirota
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Ikura
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Iwai
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000532:radiotherapy* / Q000601:surgery; D001650:Bile Duct Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D017734:Bile Ducts, Extrahepatic / Q000473:pathology* / Q000601:surgery; D001653:Bile Ducts, Intrahepatic / Q000473:pathology* / Q000601:surgery; D018281:Cholangiocarcinoma / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D013997:Time Factors; D016896:Treatment Outcome