title: Necrotizing fasciitis caused by Streptococcus pneumoniae in mixed connective tissue disease.
abstract: Abstract A 42-year-old man was hospitalized because of chills, fever, and severe polyarthralgia. He had a 5-year history of mixed connective tissue disease (MCTD) with polyarthritis which had been treated with a nonsteroidal anti-inflammatory drug alone. On the second day of hospitalization, necrotizing fasciitis of the right leg developed. Streptococcus pneumoniae was later detected in a blood culture. Pneumococcal infections of the soft tissues are uncommon, and have been reported in immunosuppressed patients and patients with systemic lupus erythematosus. This is the first report of a case of necrotizing fasciitis caused by S. pneumoniae in a patient with MCTD.
authors.affiliation: Division of Rheumatology, Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba , 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575 , Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yuhara
authors.forename: H
authors.initials: H
authors.lastname: Takemura
authors.forename: T
authors.initials: T
authors.lastname: Akama
authors.forename: K
authors.initials: K
authors.lastname: Yamane
authors.forename: T
authors.initials: T
authors.lastname: Sumida