title: Automated glycopeptide assembly by combined solid-phase peptide and oligosaccharide synthesis.
abstract: Current strategies for the synthesis of glycopeptides require multiple manual synthetic steps. Here, we describe a synthesis concept that merges solid phase peptide and oligosaccharide syntheses and can be executed automatically using a single instrument.
authors.affiliation: Max-Planck-Institute of Colloids and Interfaces, Department of Biomolecular Systems, Am Mühlenberg 1, 14476 Potsdam, Germany. peter.seeberger@mpikg.mpg.de.
authors.forename: Mattan
authors.initials: M
authors.lastname: Hurevich
authors.forename: Peter H
authors.initials: PH
authors.lastname: Seeberger
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D001331:Automation; D006020:Glycopeptides / Q000138:chemical synthesis* / Q000737:chemistry; D009005:Monosaccharides / Q000737:chemistry; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D060327:Solid-Phase Synthesis Techniques / Q000379:methods*
chemical_list: D000596:Amino Acids; D006020:Glycopeptides; D009005:Monosaccharides; D009844:Oligosaccharides