title: The genome sequence of a novel simian adenovirus in a chimpanzee reveals a close relationship to human adenoviruses.
abstract: Recently, several reports have revealed that some simian adenoviruses (AdVs) strains show a close relationship to human AdVs. In the present study, a simian AdV strain named SAdV-ch1 was detected in chimpanzees in China, and its complete genome was determined. Phylogenetic analysis revealed SAdV-ch1 clustering in a clade that was separate from all of the other simian AdVs but genetically close to a human AdV strain, HAdV-18 (GenBank no. GU191019), sharing 92.5 % sequence identity with it. Recombination analysis provided evidence that a recombination event had occurred between SAdV-ch1 and HAdV-61 (JF964962), where SAdV-ch1 exchanged partial of its hexon gene segment with HAdV-61, leading to the recombinant HAdV-31 (AM749299).
authors.affiliation: School of Medical Science and Laboratory Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013, Jiangsu, China.
authors.forename: Chenglin
authors.initials: C
authors.lastname: Zhou
authors.forename: Hua
authors.initials: H
authors.lastname: Tian
authors.forename: Xiaochun
authors.initials: X
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Shixing
authors.initials: S
authors.lastname: Yang
authors.forename: Quan
authors.initials: Q
authors.lastname: Shen
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Bin
authors.initials: B
authors.lastname: Ni
authors.forename: Shengxia
authors.initials: S
authors.lastname: Chen
authors.forename: Xingli
authors.initials: X
authors.lastname: Fu
authors.forename: Rongmei
authors.initials: R
authors.lastname: Fei
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000260:Adenoviruses, Human / Q000145:classification / Q000235:genetics*; D000261:Adenoviruses, Simian / Q000145:classification / Q000235:genetics*; D000818:Animals; D018420:Ape Diseases / Q000821:virology*; D016679:Genome, Viral; D006801:Humans; D002679:Pan troglodytes; D010802:Phylogeny