title: Immunosuppressive therapy in immune-mediated liver disease in the non-transplanted patient.
abstract: Autoimmune liver disease management goals are primarily slowing disease progression and symptomatic treatment. There are few options for curative medical management other than transplant for a spectrum of autoimmune liver disease that encompasses autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis as well as their overlap syndromes. These diseases are managed primarily with immunosuppressive therapy. Herein, we review the current literature, detailing the promise and pitfalls of the recommended immunosuppressive therapy for these challenging diseases.
authors.affiliation: Department of Medicine, St. Elizabeth's Medical Center, Tufts University School of Medicine, 736 Cambridge Street, Brighton, MA 02135, USA. anita_abhy@hotmail.co.uk.
authors.forename: Anita
authors.initials: A
authors.lastname: Abhyankar
authors.affiliation: Department of Medicine, St. Elizabeth's Medical Center, Tufts University School of Medicine, 736 Cambridge Street, Brighton, MA 02135, USA. etapper@bidmc.harvard.edu.
authors.forename: Elliot
authors.initials: E
authors.lastname: Tapper
authors.affiliation: Department of Medicine, St. Elizabeth's Medical Center, Tufts University School of Medicine, 736 Cambridge Street, Brighton, MA 02135, USA. abonder@bidmc.harvard.edu.
authors.forename: Alan
authors.initials: A
authors.lastname: Bonder