title: IgG4-related leptomeningitis: a reversible cause of rapidly progressive cognitive decline.
abstract: Immunoglobulin G4-related diseases (IgG4-RD) are a newly recognized category of diseases. CNS involvement in IgG4-RD includes hypophysitis(1) and intracranial or spinal manifestations of hypertrophic pachymeningitis.(2,3) We present a unique case of rapid cognitive decline due to IgG4-related leptomeningitis.
authors.affiliation: From the Medical College of Georgia, Georgia Regents University, Augusta.
authors.forename: Shyamal H
authors.initials: SH
authors.lastname: Mehta
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Switzer
authors.forename: Paul
authors.initials: P
authors.lastname: Biddinger
authors.forename: Amyn M
authors.initials: AM
authors.lastname: Rojiani
mesh_terms: D000368:Aged; D020274:Autoimmune Diseases of the Nervous System / Q000150:complications / Q000175:diagnosis / Q000276:immunology*; D001706:Biopsy; D001921:Brain / Q000473:pathology; D003072:Cognition Disorders / Q000209:etiology / Q000276:immunology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008279:Magnetic Resonance Imaging; D008578:Meninges / Q000473:pathology; D008581:Meningitis / Q000150:complications / Q000175:diagnosis / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G