title: Acta from the EndoFLIP® Symposium.
abstract: Laparoscopic fundoplication (LF) is a surgical treatment for gastroesophageal reflux disease (GERD) that has been performed for more than 20 years. High-volume centers of excellence report long-term success rates greater than 90% with LF. On the other hand, general population-based outcomes are reported to be markedly worse, leading to a nihilistic perception of the procedure on the part of the medical referral population. The lack of standardization of the technique and the lack of tools to calibrate objectively the repairs are probably among the causes of variability in the outcomes and may explain the decline in the number of LF procedures in recent years. The functional lumen imaging probe (EndoFLIP(®)) device is essentially a "smart bougie" in the form of a balloon catheter that measures shape and compliance of the gastroesophageal junction (GEJ) during surgery using impedance planimetry. With approximately 3 years of international experience gained with this tool, a symposium was convened in October 2012 in Strasbourg, France, with the aim of determining if intraoperative EndoFLIP use could provide standardization of surgical treatment of GERD through the understanding of physiological changes occurring to the GEJ during fundoplication. This article provides a brief history of the EndoFLIP system and reviews data previously published on the use of EndoFLIP to characterize the GEJ in normal subjects. It then summarizes the data from the 5 high-volume international sites with expert surgeons performing LF presented in Strasbourg to objectively profile the characteristics of a normal postoperative GEJ.
authors.affiliation: 1IRCAD, Department of Digestive and Endocrine Surgery, University of Strasbourg, Strasbourg, France.
authors.forename: Silvana
authors.initials: S
authors.lastname: Perretta
authors.forename: Oliver
authors.initials: O
authors.lastname: McAnena
authors.forename: Abrie
authors.initials: A
authors.lastname: Botha
authors.forename: Leslie
authors.initials: L
authors.lastname: Nathanson
authors.forename: Lee
authors.initials: L
authors.lastname: Swanstrom
authors.forename: Nathaniel J
authors.initials: NJ
authors.lastname: Soper
authors.forename: Haruiro
authors.initials: H
authors.lastname: Inoue
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Ponsky
authors.forename: Blair
authors.initials: B
authors.lastname: Jobe
authors.forename: Jacques
authors.initials: J
authors.lastname: Marescaux
authors.forename: Bernard
authors.initials: B
authors.lastname: Dallemagne
mesh_terms: D004945:Esophagoscopy / Q000295:instrumentation / Q000379:methods*; D018662:Fundoplication / Q000295:instrumentation / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000601:surgery; D006801:Humans; D012189:Retrospective Studies; D025321:Surgery, Computer-Assisted
keywords: esophageal surgery; flexible endoscopy; image guided surgery