title: Investigation of tissue thermal damage process with application of direct sensitivity method.
abstract: In the paper the numerical analysis of thermal processes proceeding in the biological tissue is presented. The tissue is subjected to the external heat flux and 2D problem is taken into account. In order to determine the influence of variations of thermophysical parameters of tissue on the value of Arrhenius injury integral the direct approach of sensitivity analysis is applied. On the basis of tissue damage fraction the thermal injury formation process is analysed. At the stage of numerical realization the boundary element method is used. In the final part of the paper the example of numerical simulation is shown.
authors.affiliation: Institute of Computational Mechanics and Engineering, Silesian University of Technology, Konarskiego18A, 44-100 Gliwice, Poland. marek.jasinski@polsl.pl
authors.forename: Marek
authors.initials: M
authors.lastname: Jasiński
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity; D001831:Body Temperature; D001833:Body Temperature Regulation; D002056:Burns / Q000503:physiopathology*; D003198:Computer Simulation; D006801:Humans; D008954:Models, Biological; D012039:Regional Blood Flow; D013814:Thermal Conductivity