title: A gastrointestinal stromal tumor of the third portion of the duodenum treated by wedge resection: A case report.
abstract: A 65-year old woman was admitted to our hospital with abdominal pain. Computed tomography showed a tumor measuring about 3 cm in diameter with no metastatic lesion or signs of local infiltration. Gastroduodenal endoscopy revealed the presence of a submucosal tumor in the third portion of the duodenum and biopsy revealed tumor cells stained positive for c-kit. These findings were consistent with gastrointestinal stromal tumors (GISTs) and we performed a wedge resection of the duodenum, sparing the pancreas. The postoperative course was uneventful and she was discharged on day 6. Surgical margins were negative. Histology revealed a GIST with a diameter of 3.2 cm and < 5 mitoses/50 high power fields, indicating a low risk of malignancy. Therefore, adjuvant therapy with imatinib was not initiated. Wedge resection with primary closure is a surgical procedure that can be used to treat low malignant potential neoplasms of the duodenum and avoid extensive surgery, with significant morbidity and possible mortality, such as pancreatoduodenectomy.
authors.affiliation: Fahrettin Acar, Mustafa Sahin, Akın Calisir, Department of General Surgery, Faculty of Medicine, Selcuk University Konya, Konya 42075, Turkey.
authors.forename: Fahrettin
authors.initials: F
authors.lastname: Acar
authors.affiliation: Fahrettin Acar, Mustafa Sahin, Akın Calisir, Department of General Surgery, Faculty of Medicine, Selcuk University Konya, Konya 42075, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Sahin
authors.affiliation: Fahrettin Acar, Mustafa Sahin, Akın Calisir, Department of General Surgery, Faculty of Medicine, Selcuk University Konya, Konya 42075, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Ugras
authors.affiliation: Fahrettin Acar, Mustafa Sahin, Akın Calisir, Department of General Surgery, Faculty of Medicine, Selcuk University Konya, Konya 42075, Turkey.
authors.forename: Akın
authors.initials: A
authors.lastname: Calisir
keywords: Duodenum; Gastrointestinal stromal tumor; Surgery; Wedge resection