title: Avian influenza H9N2 seroprevalence among swine farm residents in China.
abstract: In parts of southern China, some large-scale swine farms are adjacent to lakes and ponds that are home to many types of birds. Some swine farms will also raise poultry for consumption and sale. Swine farms in rural China may be the source of the AIV outbreak. A seroepidemiological study was conducted among swine farm residents to understand the prevalence of antibodies against avian influenza virus (AIV) H9N2 in southern China. A total of 2,006 swine farm residents were sampled. Serum samples were tested for the presence of antibodies against H9N2 AIV by hemagglutination inhibition (HI) and microneutralization assays. A total of 37 serum samples from swine farm residents were HI positive for A/chicken/Guangdong/V/2008(H9N2), and 24 serum samples (all of which were also HI positive) were microneutralization assays positive for A/chicken/Guangdong/V/2008(H9N2). Due to the special pig farming model in southern China, the residents are in close contact with different kinds of birds. Thus, controlling bird-to-human transmission of AIV in swine farms with poultry may be an important means of preventing widespread AIV infection in humans.
authors.affiliation: Key Laboratory of Animal Disease Control and Prevention of the Ministry of Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
authors.forename: Pei
authors.initials: P
authors.lastname: Zhou
authors.forename: Wanjun
authors.initials: W
authors.lastname: Zhu
authors.forename: Honglang
authors.initials: H
authors.lastname: Gu
authors.forename: Xinliang
authors.initials: X
authors.lastname: Fu
authors.forename: Lifang
authors.initials: L
authors.lastname: Wang
authors.forename: Yun
authors.initials: Y
authors.lastname: Zheng
authors.forename: Shuyi
authors.initials: S
authors.lastname: He
authors.forename: Changwen
authors.initials: C
authors.lastname: Ke
authors.forename: Heng
authors.initials: H
authors.lastname: Wang
authors.forename: Ziguo
authors.initials: Z
authors.lastname: Yuan
authors.forename: Zhangyong
authors.initials: Z
authors.lastname: Ning
authors.forename: Wenbao
authors.initials: W
authors.lastname: Qi
authors.forename: Shoujun
authors.initials: S
authors.lastname: Li
authors.forename: Guihong
authors.initials: G
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000822:Animal Husbandry; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D001715:Bird Diseases / Q000635:transmission / Q000821:virology; D002648:Child; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D005260:Female; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D053127:Influenza A Virus, H9N2 Subtype / Q000276:immunology*; D007252:Influenza Vaccines; D005585:Influenza in Birds / Q000635:transmission / Q000821:virology; D007251:Influenza, Human / Q000453:epidemiology / Q000276:immunology* / Q000821:virology; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D011200:Poultry; D016036:Seroepidemiologic Studies; D013552:Swine; D014611:Vaccination; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007252:Influenza Vaccines
keywords: H9N2; antibodies; avian influenza virus