title: [Long-term survival of a patient with locally advanced unresectable pancreatic cancer treated with gemcitabine after chemoradiation therapy].
abstract: We report a case of long-term survival of a patient with locally advanced unresectable pancreatic cancer treated with gemcitabine after chemoradiation therapy( CRTx). A 61-year-old woman was diagnosed as having locally advanced unresectable pancreatic cancer, 3.0 cm in diameter, which had invaded the superior mesenteric artery by computed tomography (CT). She was treated with CRTx( gemcitabine[ GEM] at 250 mg/m2/week for 6 weeks+liniac irradiation of 50.2 Gy) followed by systemic chemotherapy (gemcitabine (GEM) at 1,000 mg/m2). Reassessment after CRTx yielded a diagnosis of stable disease (according to the Response Evaluation Criteria in Solid Tumors [RECIST] 1.1). To date, the patient has undergone 57 courses of chemotherapy in the outpatient clinic; however, she did require biliary stent placement because of occlusive jaundice.
authors.affiliation: Dept. of Surgery, Kinki Central Hospital.
authors.forename: Teruhiro
authors.initials: T
authors.lastname: Chohno
authors.forename: Taro
authors.initials: T
authors.lastname: Aoki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hyuga
authors.forename: Risa
authors.initials: R
authors.lastname: Watanabe
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Takemoto
authors.forename: Kou
authors.initials: K
authors.lastname: Takachi
authors.forename: Kiyonori
authors.initials: K
authors.lastname: Nishioka
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Uemura
authors.forename: Kenji
authors.initials: K
authors.lastname: Kobayashi
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D059248:Chemoradiotherapy; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D010190:Pancreatic Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome; D000093542:Gemcitabine
chemical_list: D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000093542:Gemcitabine