title: Use of intraoperative cell-salvage for autologous blood transfusions in metastatic spine tumour surgery: a systematic review.
abstract: Metastatic spine tumour surgery (MSTS) and metastatic musculoskeletal tumour surgery (MMTS) are associated with substantial blood loss. Allogeneic blood transfusion is the present method used to replenish this blood. Intraoperative cell salvage (IOCS) is a viable alternative, but is contraindicated in tumour surgery because of the risk of tumour dissemination. Use of IOCS-leucocyte depletion filter (LDF) allows removal of tumour cells from blood salvaged during oncological surgery. However, no reports exist on use of IOCS in MSTS or MMTS. We systematically reviewed studies on IOCS in oncological surgery to investigate whether sufficient evidence exists to support its use in MSTS or MMTS.
authors.affiliation: National University Health System, Singapore, Singapore. Electronic address: Naresh_Kumar@nuhs.edu.sg.
authors.forename: Naresh
authors.initials: N
authors.lastname: Kumar
authors.affiliation: National University Health System, Singapore, Singapore.
authors.forename: Yongsheng
authors.initials: Y
authors.lastname: Chen
authors.affiliation: National University Health System, Singapore, Singapore.
authors.forename: Aye S
authors.initials: AS
authors.lastname: Zaw
authors.affiliation: National University Health System, Singapore, Singapore.
authors.forename: Deepti
authors.initials: D
authors.lastname: Nayak
authors.affiliation: National University Hospital, Singapore, Singapore.
authors.forename: Qasim
authors.initials: Q
authors.lastname: Ahmed
authors.affiliation: National University Hospital, Singapore, Singapore.
authors.forename: Richie
authors.initials: R
authors.lastname: Soong
authors.affiliation: National University Health System, Singapore, Singapore.
authors.forename: Hee K
authors.initials: HK
authors.lastname: Wong
mesh_terms: D001804:Blood Transfusion, Autologous / Q000379:methods*; D001859:Bone Neoplasms / Q000601:surgery; D005770:Gastrointestinal Neoplasms / Q000601:surgery; D006801:Humans; D007432:Intraoperative Period; D047589:Leukocyte Reduction Procedures; D008113:Liver Neoplasms / Q000601:surgery; D008175:Lung Neoplasms / Q000556:secondary; D009362:Neoplasm Metastasis; D013125:Spinal Neoplasms / Q000473:pathology / Q000601:surgery*; D014571:Urologic Neoplasms / Q000601:surgery