title: [Is standard radical mastectomy still a treatment option for select patients with breast cancer ?].
abstract: BACKGROUND
  Currently, minimal surgery is the treatment of choice for most breast cancer patients. However, some patients with locally advanced breast cancer( LABC) require standard radical mastectomy( SRM) before or after systemic therapy.
  
  
  METHODS
  We reviewed the medical records of 7 patients with breast cancer who underwent SRM in our hospital between January 2007 and April 2013 and examined their clinicopathological features and prognostic outcomes.
  
  
  RESULTS
  The average patient age was 68 years. SRM was performed because of muscle invasion( n=6), Rotter lymph node metastases( n=3), and level III lymph node metastases( n=3). After SRM, the wound was closed by skin grafting in 2 of the 7 patients. With regard to postoperative complications, 2 patients required rehabilitation for shoulder joint stiffness, whereas wound infection and arm edema were encountered in 1 and 2 patients, respectively. During the median follow-up time of 26 (range; 4-69) months, 3 patients experienced recurrence. The metastatic sites in the 3 patients were the supraclavicular lymph nodes, the chest wall, and the liver, respectively.
  
  
  CONCLUSIONS
  Quality of life( QOL) following SRM was acceptable in the patients examined. SRM could be considered as a treatment option in select patients with LABC.
authors.affiliation: Dept. of Breast Surgery, Kansai Rosai Hospital.
authors.forename: Chiyomi
authors.initials: C
authors.lastname: Egawa
authors.forename: Hiroki
authors.initials: H
authors.lastname: Kusama
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Okishiro
authors.forename: Kazuko
authors.initials: K
authors.lastname: Oku
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Goto
authors.forename: Teruaki
authors.initials: T
authors.lastname: Nagano
authors.forename: Shinichi
authors.initials: S
authors.lastname: Nakatsuka
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Takatsuka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D015409:Mastectomy, Radical / Q000009:adverse effects; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011183:Postoperative Complications / Q000453:epidemiology; D011379:Prognosis