title: Plasma free Fatty Acid concentrations as a marker for acute myocardial infarction.
abstract: BACKGROUND
  Acute myocardial infarction carries a high mortality among cardiac patients.The discovery of the fact that certain enzymes like CPK, LDH liberated into circulation following necrosis of the myocardial cells came as boon for physicians and patients. There has been a constant search of different parameters for the diagnosis and management of CoronaryArtery Diseases (CAD).
  
  
  OBJECTIVE
  The present study was undertaken to investigate a possible relation between the changes in plasma free fatty acid (FFA) concentration and acute myocardial infarction.
  
  
  METHODS
  Fifty cases (25 males and 25 females) of acute myocardial infarction were selected for the present study. All the patients were in the age group of 40-70 years. For the control group fifty (25 male and 25 female) subjects of same age group were selected from patient's relatives and friends. Plasma free fatty acid concentration was estimated by Titrametric method of Trout et al., (1960), a modified version of Dole (1956).
  
  
  METHODS
  The statistical analysis of the data of the present study was done by using SPSS, version 14.0.1 was used.
  
  
  RESULTS
  Our study showed a significant increase in plasma FFA in the first 24 hours of acute myocardial infarction with subsequent normalisation on the 7th day.The difference between the first and the seventh day was statistically significant.
  
  
  CONCLUSIONS
  The FFA were found raised in cases of acute myocardial infarction.On the basis of present study, it is worth to say that estimation of serum free fatty acid should be done routinely at the earliest opportunity in all cases of acute myocardial infarction.
authors.affiliation: Assistant Professor, Departement of Physiology, SGT Medical College, Hospital & Reaserch Institute , Budhera, Gurgaon-122505, Haryana, India .
authors.forename: Vijay Kumar
authors.initials: VK
authors.lastname: Roy
authors.affiliation: Assistant Professor, Departement of Physiology, SGT Medical College, Hospital & Reaserch Institute , Budhera, Gurgaon-122505, Haryana, India .
authors.forename: Anil
authors.initials: A
authors.lastname: Kumar
authors.affiliation: Associate Professor, Departement of Physiology, SGT Medical College, Hospital & Reaserch Institute , Budhera, Gurgaon-122505, Haryana, India .
authors.forename: Prabal
authors.initials: P
authors.lastname: Joshi
authors.affiliation: Assistant Professor, Departement of Physiology, SGT Medical College, Hospital & Reaserch Institute , Budhera, Gurgaon-122505, Haryana, India .
authors.forename: Jyoti
authors.initials: J
authors.lastname: Arora
authors.affiliation: Professor and Head, Departement of Physiology, SGT Medical College, Hospital & Reaserch Institute , Budhera, Gurgaon-122505, Haryana, India .
authors.forename: Ali Mohammad
authors.initials: AM
authors.lastname: Ahanger
keywords: Acute myocardial infarction; Coronary artery disease; FFA; Marker; Plasma free fatty acid