title: Experience with 53 portal-duodenal drained solitary pancreas transplants.
abstract: Systemic-enteric drainage is currently the most common technique for pancreas transplantation (PT). A novel alternative technique, portal-duodenal drainage (PDD), has potential physiological benefits and provides improved monitoring of the pancreatic graft. The current study describes 53 solitary PT procedures (43 pancreas after kidney and 10 pancreas transplant alone) using the PDD technique over the last three yr. This method resulted in one-yr patient survival at 96% and 83% graft survival. There were five cases (9.4%) of thrombosis, in which transplantectomy and two-layer closure of the native duodenum were performed. No fistulas were observed. Here, we demonstrate that the PDD technique in PT was as safe and effective as current techniques in clinical use.
authors.affiliation: HEPATO - Hepatology and Organ Transplantation, Bandeirantes Hospital, São Paulo, Brazil.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Perosa
authors.forename: Huda
authors.initials: H
authors.lastname: Noujaim
authors.forename: Luiz E
authors.initials: LE
authors.lastname: Ianhez
authors.forename: Rodrigo A
authors.initials: RA
authors.lastname: Oliveira
authors.forename: Leonardo T
authors.initials: LT
authors.lastname: Mota
authors.forename: Juan R
authors.initials: JR
authors.lastname: Branez
authors.forename: Marcio M
authors.initials: MM
authors.lastname: Paredes
authors.forename: Luciano
authors.initials: L
authors.lastname: Giacaglia
authors.forename: Tercio
authors.initials: T
authors.lastname: Genzini
mesh_terms: D000328:Adult; D004322:Drainage; D004386:Duodenum / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation; D010182:Pancreatic Diseases / Q000401:mortality / Q000601:surgery*; D016577:Pancreaticoduodenectomy / Q000401:mortality; D011183:Postoperative Complications; D011379:Prognosis; D015996:Survival Rate; D055815:Young Adult
keywords: duodenal drainage; pancreas transplantation