title: Haplophytin B from Maclurodendron porteri.
abstract: An alkaloid from Maclurodendron porteri has been isolated and characterized. Extraction process was conducted by acid-base extraction method followed by column chromatography. The structure was established by nuclear magnetic resonance spectroscopy and mass spectrometry. The compound was identified as haplophytin B which occurs commonly in the Rutaceae family. However, this is the first time this alkaloid was isolated and reported from the species. The compound showed no inhibition against Staphylococus aureus, Pseudomonas aeruginosa, Bacillus cereus and Escherichia coli and no cytotoxic activity against H199 and A549 cell lines.
authors.affiliation: Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Taher
authors.affiliation: Department of Chemistry, Faculty of Science, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia.
authors.forename: Deny
authors.initials: D
authors.lastname: Susanti
authors.affiliation: Department of Chemistry, Faculty of Science, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia.
authors.forename: Shafida
authors.initials: S
authors.lastname: Abd Hamid
authors.affiliation: Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia.
authors.forename: Khadijah
authors.initials: K
authors.lastname: Edueng
authors.affiliation: Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia.
authors.forename: Juliana Md
authors.initials: JM
authors.lastname: Jaffri
authors.affiliation: Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia.
authors.forename: Anugerah Budipratama
authors.initials: AB
authors.lastname: Adina
authors.affiliation: SIRIM Berhad (National Metrology Laboratory), Lot PT 4803, Bandar Baru Salak Tinggi, Sepang, Selangor, Malaysia.
authors.forename: Mohamad Fazlin
authors.initials: MF
authors.lastname: Rezali
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D006575:Heterocyclic Compounds, 3-Ring / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D027821:Rutaceae / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D006575:Heterocyclic Compounds, 3-Ring; C586562:haplophytin B