title: Conservative treatment of a young patient with thyroid carcinoma in adult ovarian teratoma - case report.
abstract: The cystic mature teratomas, including dermoid cysts, are one of the most frequently occurring benign ovarian tumors diagnosed in female patients. The process of neoplastic transformation in mature dermoid cysts is applicable only to 1-2% of cases. In our article, we present a rare case of thyroid carcinoma development in adult teratoma in 21-year-old patient. The young age, certain pathomorphological features and clinical data (small size of neoplastic lesion, correct values of tumour markers, unilateral character, regular levels of thyreoglobulin and absence of any significant deviations in imaging examinations), were the basis for attempting to apply the conservative treatment both in the scope of gynecological surgery and in the supplemental endocrinological therapy. In the patient, the one-sided adnexectomy was performed, considering pathological lesions on the adnexa, as well as the other ovary dermoid cyst was enucleated, without the hysteroctomy procedure. Considering the lack of any morphological lesions and functional changes relating to thyroid gland, the treatment was not radicalised in this scope, either. At present, one year after the primary operation treatment, the patient does not manifest any disease symptoms, whereas the other ovary, in the follow-up ultrasound examinations, shows normal size and echostructure. The thyroid-stimulating hormone (TSH) suppression keeps being applied.
authors.affiliation: Department of Gynecological Surgery and Gynecological Oncology of Adults and Adolescents .
authors.forename: Aneta
authors.initials: A
authors.lastname: Cymbaluk-Ploska
authors.forename: Anita
authors.initials: A
authors.lastname: Chudecka-Głaz
authors.forename: Maria
authors.initials: M
authors.lastname: Chosia
authors.forename: Olgierd
authors.initials: O
authors.lastname: Ashuryk
authors.forename: Janusz
authors.initials: J
authors.lastname: Menkiszak
mesh_terms: D000328:Adult; D002291:Carcinoma, Papillary / Q000188:drug therapy*; D005260:Female; D059247:Fertility Preservation; D020249:Hormone Replacement Therapy; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy / Q000601:surgery; D010051:Ovarian Neoplasms / Q000601:surgery*; D013724:Teratoma / Q000601:surgery*; D013964:Thyroid Neoplasms / Q000188:drug therapy*; D013974:Thyroxine / Q000627:therapeutic use; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D013974:Thyroxine