title: [A case of liver metastasis from esophageal cancer treated with stereotactic body radiation therapy].
abstract: A 70-year-old woman was diagnosed as having advanced lower thoracic esophageal cancer with abdominal lymph node metastases(T3N1M0, Stage III). After administering 2 courses of neoadjuvant chemotherapy with 5-fluorouracil(5- FU)( 800 mg/m2)and cisplatin(80 mg/m2), we performed curative surgery with D2 lymph node dissection. The patient could not receive adjuvant chemotherapy because of her poor performance status. After curative surgery, liver metastasis appeared in segment 8. The liver metastasis(S8)was treated with stereotactic body radiation therapy(SBRT)( 60 Gy/3 Fr). After SBRT, we administered systemic chemotherapy with docetaxel and nedaplatin as second-line chemotherapy. The patient had no recurrence for 12 months after SBRT. SBRT exhibited an excellent local therapeutic effect without any serious complications, suggesting that it is an effective treatment for liver metastasis from esophageal cancer.
authors.affiliation: Dept. of Digestive Surgery, Saiseikai Yokohamashi Tobu Hospital.
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Egawa
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Okubo
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kemmochi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Mori
authors.forename: Shinji
authors.initials: S
authors.lastname: Sato
authors.forename: Shin
authors.initials: S
authors.lastname: Nishiya
authors.forename: Koki
authors.initials: K
authors.lastname: Mihara
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ito
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Makino
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nagashima
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D059248:Chemoradiotherapy; D000077143:Docetaxel; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000532:radiotherapy* / Q000556:secondary; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D012008:Recurrence; D043823:Taxoids / Q000008:administration & dosage; D016896:Treatment Outcome; D014916:Whole-Body Irradiation
chemical_list: D009944:Organoplatinum Compounds; D043823:Taxoids; D000077143:Docetaxel; C053989:nedaplatin