title: [The activity of the interneuron pools of the spinal cord in experimental diabetes mellitus].
abstract: We analyzed threshold, chronaxy and parameters of the potential of the dorsal surface (PDP) of the spinal cord (SC) in Wistar rats with experimental diabetes mellitus (DM) and intact animals. We found a decrease in the excitation threshold by 41.4% (P < 0.05), and an increase in chronaxia by 9.5% (P < 0.01), an increase of the amplitude of the N3-component by 15.8% (P < 0.05), and an increase in the duration of the afferent peak by 4.5 % (P < 0,05) and the N2-component by 10.9% (P < 0.01) responsively. We conclude that the metabolic changes under DM lead to modification of activity of the afferent pathways and interneuron pool of SC.
authors.forename: O H
authors.initials: OH
authors.lastname: Rodyns'kyĭ
authors.forename: O H
authors.initials: OH
authors.lastname: Zinov'ieva
authors.forename: O V
authors.initials: OV
authors.lastname: Mozhunov
authors.forename: O S
authors.initials: OS
authors.lastname: Trushenko
mesh_terms: D000200:Action Potentials; D000496:Alloxan; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology*; D004558:Electric Stimulation; D007395:Interneurons / Q000378:metabolism / Q000473:pathology*; D009475:Neurons, Afferent / Q000378:metabolism / Q000473:pathology*; D051381:Rats; D017208:Rats, Wistar; D013116:Spinal Cord / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology*
chemical_list: D000496:Alloxan