title: Parameterisation affects identifiability of population models.
abstract: Identifiability is an important aspect of model development. In this work, using a simple one compartment population pharmacokinetic model, we show that identifiability of the variances of the random effects parameters are affected by the parameterisation of the fixed effects parameters.
authors.affiliation: School of Pharmacy, University of Otago, P.O. Box 56, Dunedin, 9054, New Zealand, vittal.shivva@otago.ac.nz.
authors.forename: Vittal
authors.initials: V
authors.lastname: Shivva
authors.forename: Julia
authors.initials: J
authors.lastname: Korell
authors.forename: Ian G
authors.initials: IG
authors.lastname: Tucker
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Duffull
mesh_terms: D008954:Models, Biological; D017711:Nonlinear Dynamics; D011153:Population