title: Testicular choriocarcinoma: diagnosed on cervical lymph node biopsy.
abstract: Choriocarcinoma is a very rare germinal testicular tumour and in literature its incidence has been reported to be 0.3% of all germinal testicular tumours. An important tumour marker is serum beta-hCG which not only helps in establishing diagnosis but also in assessing response to chemotherapy. In this study we present a case of testicular choriocarcinoma, who presented with abdominal pain, cough, generalized weakness and left sided cervical mass. Incisional biopsy of cervical mass was performed. Histopathology revealed metastatic choriocarcinoma. Serum beta-hCG levels were 1227 ng/mL. Patient received intravenous cycles of PEB (cisPlatin, Etoposide, Bleomycin) chemotherapy but he had progressive disease both radiologically and on tumour marker monitoring. He was planned for salvage chemotherapy but was lost to follow up there after. It is concluded that in males, choriocarcinoma carries a very dismal prognosis and a very poor response to chemotherapy and radiotherapy; surgery has no role in the management.
authors.affiliation: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad. nzabbasi@hotmail.com
authors.forename: Nadeem Zia
authors.initials: NZ
authors.lastname: Abbasi
authors.affiliation: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad.
authors.forename: Zainab
authors.initials: Z
authors.lastname: Zahur
authors.affiliation: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad.
authors.forename: Abdul Samad
authors.initials: AS
authors.lastname: Sheikh
authors.affiliation: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad.
authors.forename: Amjad Aziz
authors.initials: AA
authors.lastname: Khan
authors.affiliation: Bio-Sciences Division, PAEC HQ, Islamabad.
authors.forename: Fayyaz
authors.initials: F
authors.lastname: Ahmed
authors.affiliation: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad.
authors.forename: Khalid Hussain
authors.initials: KH
authors.lastname: Memon
authors.affiliation: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad.
authors.forename: Furqan
authors.initials: F
authors.lastname: Ali
authors.affiliation: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad.
authors.forename: Asif
authors.initials: A
authors.lastname: Jeilani
authors.affiliation: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad.
authors.forename: Tetheer
authors.initials: T
authors.lastname: Fatima
authors.affiliation: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad.
authors.forename: Kamran
authors.initials: K
authors.lastname: Khan
authors.affiliation: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad.
authors.forename: Attia
authors.initials: A
authors.lastname: Gul
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002822:Choriocarcinoma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D018450:Disease Progression; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D009333:Neck; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology