title: Metastatic pulmonary calcinosis and leukocytoclastic vasculitis in a patient with multiple myeloma.
abstract: Both leukocytoclastic vasculitis and metastatic pulmonary calcification are conditions that rarely occur during the course of multiple myeloma. We present a multiple myeloma patient that had severe dyspnea due to metastatic pulmonary calcinosis, and ulceronecrotic skin lesions caused by leukocytoclastic vasculitis. After 3 courses of standarddose chemotherapy all skin and pulmonary lesions disappeared. Autologous peripheral stem cell transplantation was performed and during 1 year of follow-up the patient was in complete remission; after 1 year, laboratory test results indicated disease relapse. Although the patient was treated with bortezomib and dexamethasone, the disease progressed. Non-myeloablative allogeneic stem cell transplantation was performed, but despite of all treatment the patient died due to disease progression.
  
  
  BACKGROUND
  None declared.
authors.affiliation: Ege University, School of Medicine, Department of Hematology, İzmir, Turkey.
authors.forename: Seçkin
authors.initials: S
authors.lastname: Cağırgan
authors.affiliation: Ege University, School of Medicine, Department of Hematology, İzmir, Turkey.
authors.forename: Nur
authors.initials: N
authors.lastname: Soyer
authors.affiliation: Ege University, School of Medicine, Department of Hematology, İzmir, Turkey.
authors.forename: Filiz
authors.initials: F
authors.lastname: Vural
authors.affiliation: Ege University, School of Medicine, Department of Hematology, İzmir, Turkey.
authors.forename: Güray
authors.initials: G
authors.lastname: Saydam
authors.affiliation: Ege University, School of Medicine, Department of Hematology, İzmir, Turkey.
authors.forename: Ilgın
authors.initials: I
authors.lastname: Yıldırım Şimşir
authors.affiliation: Ege University, School of Medicine, Department of Hematology, İzmir, Turkey.
authors.forename: Ayhan
authors.initials: A
authors.lastname: Dönmez
authors.affiliation: Ege University, School of Medicine, Department of Pathology, İzmir, Turkey.
authors.forename: Taner
authors.initials: T
authors.lastname: Akalın
authors.affiliation: Ege University, School of Medicine, Department of Radiology, İzmir, Turkey.
authors.forename: Selen
authors.initials: S
authors.lastname: Biçeroğlu
authors.affiliation: Ege University, School of Medicine, Department of Hematology, İzmir, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Tombuloğlu
keywords: Leukocytoclastic vasculitis; Metastatic calcification; Multiple myeloma