title: Ultra-dense EEG sampling results in two-fold increase of functional brain information.
abstract: Contemporary high-density electroencephalographic systems (hd-EEG) comprising up to 256 electrodes have inter-electrode separations of 2-4 cm. Because electric currents of the brain are believed to strongly diffuse before reaching the scalp surface, higher-density electrode coverage is often deemed unnecessary. We used an ultra-dense electroencephalography (ud-EEG) sensor array to reveal strong potential variation at 1cm scale and discovered that it reflects functional brain activity. A new classification paradigm demonstrates that ud-EEG provides twice the signal to noise ratio for brain-response classification compared with contemporary hd-EEG. These results suggest a paradigm shift from current thinking by showing that higher spatial resolution sampling of EEG is required and leads to increased functional brain information that is useful for diverse neurological applications.
authors.affiliation: Northeastern University, Boston, MA 02115, USA. Electronic address: yury@ski.org.
authors.forename: Yury
authors.initials: Y
authors.lastname: Petrov
authors.affiliation: Northeastern University, Boston, MA 02115, USA.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Nador
authors.affiliation: Northeastern University, Boston, MA 02115, USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Hughes
authors.affiliation: Northeastern University, Boston, MA 02115, USA.
authors.forename: Stanley
authors.initials: S
authors.lastname: Tran
authors.affiliation: Northeastern University, Boston, MA 02115, USA.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Yavuzcetin
authors.affiliation: Northeastern University, Boston, MA 02115, USA.
authors.forename: Srinivas
authors.initials: S
authors.lastname: Sridhar
mesh_terms: D000328:Adult; D000465:Algorithms; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D004566:Electrodes; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation; D012815:Signal Processing, Computer-Assisted; D055815:Young Adult