title: In vitro efficacy of a novel active-release antimicrobial coating to eradicate biofilms of Pseudomonas aeruginosa.
abstract: Implant-related infections are becoming increasingly difficult to treat due to the formation of biofilms on implant surfaces. This study analyzed the in vitro efficacy of a novel antimicrobial coating against biofilms of Pseudomonas aeruginosa, using a flow cell system. Results indicated that P. aeruginosa biofilms were reduced by greater than 8 log10 units in less than 24 h. Data indicated that this active-release coating may be promising for preventing biofilm implant-related infections.
authors.affiliation: George E. Wahlen Department of Veterans Affairs, Salt Lake City, Utah, USA.
authors.forename: Dustin L
authors.initials: DL
authors.lastname: Williams
authors.forename: Julia M
authors.initials: JM
authors.lastname: Lerdahl
authors.forename: Bryan S
authors.initials: BS
authors.lastname: Haymond
authors.forename: Roy D
authors.initials: RD
authors.lastname: Bloebaum
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects*; D019736:Prostheses and Implants / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects*
chemical_list: D000890:Anti-Infective Agents