title: Cerebral blood flow of children with vasovagal syncope.
abstract: BACKGROUND
  We aimed to evaluate changes in the cerebral blood supply in children during vasovagal syncope and to clarify the diagnostic value of transcranial Doppler for vasovagal syncope.
  
  
  METHODS
  Patients were divided into three groups. Group 1 consisted of 31 patients who were symptomatic and whose head-up tilt test was positive. Group 2 comprised 21 patients who were symptomatic but whose tilt test was negative. Group 3 included 22 healthy children. For the diagnosis of vasovagal syncope, the tilt test was applied. For the subjects of the patient and control groups, the tilt test was repeated. The flow rates of bilateral middle cerebral arteries were continuously and simultaneously recorded with temporal window transcranial Doppler.
  
  
  RESULTS
  There were no statistically significant differences between the three groups with respect to age and gender distribution (p>0.05). When the bed was at an upright position, the maximum blood flow rate of the right middle cerebral artery was lower in Group 1 than in Group 2, although the decrease was more significant in comparison to the healthy control group (p<0.05). The minimum blood flow rate of the right middle cerebral artery was lower in Group 1 than the Group 2, although the decrease was more significant in comparison with the healthy control group (p<0.05). The maximum blood flow rate of the left middle cerebral artery was significantly lower in Group 1 than in the control group (p<0.05).
  
  
  CONCLUSIONS
  Minimum and maximum blood flow rates are significantly decreased in patients tilt test (+) patients with vasovagal syncope during orthostatic stress.
authors.affiliation: 1Department of Pediatric Cardiology,Eskisehir Osmangazi University,Eskisehir,Turkey.
authors.forename: Barsan
authors.initials: B
authors.lastname: Tugba
authors.affiliation: 1Department of Pediatric Cardiology,Eskisehir Osmangazi University,Eskisehir,Turkey.
authors.forename: Kilic
authors.initials: K
authors.lastname: Zubeyir
authors.affiliation: 2Department of Neurology,Eskisehir Osmangazi University,Eskisehir,Turkey.
authors.forename: Uzuner
authors.initials: U
authors.lastname: Nevzat
authors.affiliation: 1Department of Pediatric Cardiology,Eskisehir Osmangazi University,Eskisehir,Turkey.
authors.forename: Yildirim
authors.initials: Y
authors.lastname: Ali
authors.affiliation: 1Department of Pediatric Cardiology,Eskisehir Osmangazi University,Eskisehir,Turkey.
authors.forename: Ucar
authors.initials: U
authors.lastname: Birsen
authors.affiliation: 1Department of Pediatric Cardiology,Eskisehir Osmangazi University,Eskisehir,Turkey.
authors.forename: Demir
authors.initials: D
authors.lastname: Tevfik
mesh_terms: D000293:Adolescent; D001783:Blood Flow Velocity; D001921:Brain / Q000098:blood supply*; D016022:Case-Control Studies; D002560:Cerebrovascular Circulation; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging*; D019462:Syncope, Vasovagal / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology*; D018667:Tilt-Table Test; D017585:Ultrasonography, Doppler, Transcranial
keywords: children