title: [A case of gastric cancer with intensive peritoneal dissemination treated with long-term chemotherapy and surgery].
abstract: A 45-year-old man was transferred to our hospital because of advanced gastric cancer and peritoneal dissemination. After he received an S-1 plus cisplatin( CDDP) regimen for 6 courses, the primary lesion and ascites had disappeared. However, the primary lesion recurred, and he underwent treatment with 16 courses of an S-1 plus docetaxel regimen. He subsequently developed peripheral neuropathy, and was switched to the irinotecan (CPT-11) regimen. As he experienced appetite loss, it was impossible to continue the chemotherapy. Therefore, he underwent a salvage surgery and an R0 resection was performed. However, 9 months after the surgery, he experienced paraaortic lymph node recurrence and peritoneal dissemination. The patient died 13 months after the surgery.
authors.affiliation: Dept. of Gastrointestinal Surgery, Kanagawa Cancer Center.
authors.forename: Junya
authors.initials: J
authors.lastname: Shirai
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Cho
authors.forename: Hirohito
authors.initials: H
authors.lastname: Fujikawa
authors.forename: Kenichi
authors.initials: K
authors.lastname: Iwasaki
authors.forename: Takashi
authors.initials: T
authors.lastname: Ogata
authors.forename: Takaki
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Akira
authors.initials: A
authors.lastname: Tsuburaya
authors.forename: Ken
authors.initials: K
authors.lastname: Sujishi
authors.forename: Takanobu
authors.initials: T
authors.lastname: Yamada
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Osaragi
authors.forename: Katsuya
authors.initials: K
authors.lastname: Yoneyama
authors.forename: Akio
authors.initials: A
authors.lastname: Kasahara
authors.forename: Yuji
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Rino
authors.forename: Munetaka
authors.initials: M
authors.lastname: Masuda
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D000077143:Docetaxel; D004338:Drug Combinations; D017809:Fatal Outcome; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D016879:Salvage Therapy; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D043823:Taxoids / Q000008:administration & dosage; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D043823:Taxoids; C079198:S 1 (combination); D005641:Tegafur; D000077143:Docetaxel; D010094:Oxonic Acid