title: Effect of high-frequency chest wall oscillation versus chest physiotherapy on lung function after lung transplant.
abstract: OBJECTIVE
  The aim of this study is to compare the effects of chest physiotherapy (CPT) and high-frequency chest wall oscillation (HFCWO) on lung function in lung transplant recipients.
  
  
  BACKGROUND
  Chest physiotherapy and HFCWO are routinely used after lung transplant to attenuate dyspnea, increase expiratory flow, and improve secretion clearance.
  
  
  METHODS
  In a two-group experimental, crossover design with repeated-measures, 45 lung transplant recipients (27 single, 18 bilateral; 64% male; mean age, 57 years) were randomized to receive CPT at 10:00 AM and 2:00 PM followed by HFCWO at 6:00 PM and 10:00 PM (n=22) or vice versa (n=23) on postoperative day 3. Dyspnea (modified Borg score), Spo2/FiO2, and peak expiratory flow (PEF) were measured pre-treatment and post-treatment. Data were analyzed using chi-square tests, t tests, and linear mixed effects models.
  
  
  RESULTS
  There was no statistically significant treatment effect for dyspnea or PEF in patients who received HFCWO versus CPT. However, there was a significant treatment effect on the Spo2/FiO2 ratio (p<0.0001).
  
  
  CONCLUSIONS
  Preliminary results suggest that lung function (measured by Spo2/FiO2) improves with HFWCO after lung transplantation. Although dyspnea and PEF did not differ significantly between treatment types, HFCWO may be an effective, feasible alternative to CPT.
authors.affiliation: Department of Nursing, Cardiothoracic Intensive Care Unit, Ronald Reagan-UCLA Medical Center, Los Angeles, California. Electronic address: aesguerra-gonzalez@mednet.ucla.edu.
authors.forename: Angeli
authors.initials: A
authors.lastname: Esguerra-Gonzales
authors.affiliation: Department of Nursing, Cardiothoracic Intensive Care Unit, Ronald Reagan-UCLA Medical Center, Los Angeles, California. Electronic address: mIlagan-honorio@mednet.ucla.edu.
authors.forename: Monina
authors.initials: M
authors.lastname: Ilagan-Honorio
authors.affiliation: School of Nursing, UCLA, Los Angeles, California. Electronic address: pkehoe@sonnet.ucla.edu.
authors.forename: Priscilla
authors.initials: P
authors.lastname: Kehoe
authors.affiliation: Transplant Services, Heart and Lung Transplantation, UCLA Health System, Los Angeles, California. Electronic address: sfranschilla@mednet.ucla.edu.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Fraschilla
authors.affiliation: Department of Nursing, Cardiothoracic Intensive Care Unit, Ronald Reagan-UCLA Medical Center, Los Angeles, California. Electronic address: leeaijin@gmail.com.
authors.forename: Ai Jin
authors.initials: AJ
authors.lastname: Lee
authors.affiliation: Department of Nursing, Cardiothoracic Intensive Care Unit, Ronald Reagan-UCLA Medical Center, Los Angeles, California. Electronic address: amadsen@mednet.ucla.edu.
authors.forename: Ashley
authors.initials: A
authors.lastname: Madsen
authors.affiliation: Department of Nursing, Cardiothoracic Intensive Care Unit, Ronald Reagan-UCLA Medical Center, Los Angeles, California. Electronic address: tmarcarian@mednet.ucla.edu.
authors.forename: Taline
authors.initials: T
authors.lastname: Marcarian
authors.affiliation: Department of Nursing, Cardiothoracic Intensive Care Unit, Ronald Reagan-UCLA Medical Center, Los Angeles, California. Electronic address: kmayol-ngo@mednet.ucla.edu.
authors.forename: Kristina
authors.initials: K
authors.lastname: Mayol-Ngo
authors.affiliation: School of Nursing, UCLA, Los Angeles, California. Electronic address: Pamela.Miller@nursing.ucsf.edu.
authors.forename: Pamela S
authors.initials: PS
authors.lastname: Miller
authors.affiliation: Transplant Services, Heart and Lung Transplantation, UCLA Health System, Los Angeles, California. Electronic address: jonga@mednet.ucla.edu.
authors.forename: Jay
authors.initials: J
authors.lastname: Onga
authors.affiliation: Department of Nursing, Cardiothoracic Intensive Care Unit, Ronald Reagan-UCLA Medical Center, Los Angeles, California. Electronic address: brodman@mednet.ucla.edu.
authors.forename: Betty
authors.initials: B
authors.lastname: Rodman
authors.affiliation: Division of Pulmonary and Critical Care Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California. Electronic address: dross@mednet.ucla.edu.
authors.forename: David
authors.initials: D
authors.lastname: Ross
authors.affiliation: Department of Nursing, Cardiothoracic Intensive Care Unit, Ronald Reagan-UCLA Medical Center, Los Angeles, California. Electronic address: zshameem@mednet.ucla.edu.
authors.forename: Zeba
authors.initials: Z
authors.lastname: Shameem
authors.affiliation: School of Nursing, UCLA, Los Angeles, California; Department of Biostatistics, School of Public Health, UCLA, Los Angeles, California. Electronic address: knandy@sonnet.ucla.edu.
authors.forename: Karabi
authors.initials: K
authors.lastname: Nandy
authors.affiliation: School of Nursing, UCLA, Los Angeles, California; Department of Biostatistics, School of Public Health, UCLA, Los Angeles, California. Electronic address: jtoyama@sonnet.ucla.edu.
authors.forename: Joy
authors.initials: J
authors.lastname: Toyama
authors.affiliation: Department of Nursing, Cardiothoracic Intensive Care Unit, Ronald Reagan-UCLA Medical Center, Los Angeles, California. Electronic address: ssommer@mednet.ucla.edu.
authors.forename: Susan
authors.initials: S
authors.lastname: Sommer
authors.affiliation: Department of Nursing, Cardiothoracic Intensive Care Unit, Ronald Reagan-UCLA Medical Center, Los Angeles, California. Electronic address: ctamonang@mednet.ucla.edu.
authors.forename: Cheryl
authors.initials: C
authors.lastname: Tamonang
authors.affiliation: Department of Nursing, Cardiothoracic Intensive Care Unit, Ronald Reagan-UCLA Medical Center, Los Angeles, California. Electronic address: fvillamor@mednet.ucla.edu.
authors.forename: Filma
authors.initials: F
authors.lastname: Villamor
authors.affiliation: Division of Pulmonary and Critical Care Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California. Electronic address: sweigt@mednet.ucla.edu.
authors.forename: S Samuel
authors.initials: SS
authors.lastname: Weigt
authors.affiliation: School of Nursing, UCLA, Los Angeles, California. Electronic address: agawlins@sonnet.ucla.edu.
authors.forename: Anna
authors.initials: A
authors.lastname: Gawlinski
mesh_terms: D000368:Aged; D035641:Chest Wall Oscillation; D018592:Cross-Over Studies; D005260:Female; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D016040:Lung Transplantation; D008297:Male; D026741:Physical Therapy Modalities
keywords: Chest physiotherapy; High frequency chest wall oscillation; Lung transplant; Post-lung transplant; Pulmonary hygiene