title: Outcomes of biomarker feedback on physical activity, eating habits, and emotional health: from the Americans in Motion-Healthy Intervention (AIM-HI) study.
abstract: OBJECTIVE
  The purpose of this article was to test whether physical activity, healthy eating, and emotional well-being would improve if patients received feedback about biomarkers that have been shown to be responsive to changes in weight and fitness.
  
  
  METHODS
  Patients were randomized to limited feedback (weight, body mass index [BMI], and blood pressure at 4 and 10 months) or enhanced feedback (weight, BMI, blood pressure, homeostatic insulin resistance, and nuclear magnetic resonance lipoprotein profiles at 2, 4, 7, and 10 months). Repeated measures mixed effects multivariate regression models were used to determine whether BMI, fitness, diet, and quality of life changed over time.
  
  
  RESULTS
  Major parameters were similar in both groups at baseline. BMI, measures of fitness, healthy eating, quality of life, and health state improved in both patient groups, but there was no difference between patient groups at 4 or 10 months. Systolic blood pressure improved in the enhanced feedback group, and there was a difference between the enhanced and limited feedback groups at 10 months (95% confidence interval, -6.011 to -0.5113).
  
  
  CONCLUSIONS
  Providing patients with enhanced feedback did not dramatically change outcomes. However, across groups, many patients maintained or lost weight, suggesting the need for more study of nondiet interventions.
authors.affiliation: the Department of Medicine, Division of General Internal Medicine, Colorado Health Outcome Program, and Anschutz Health and Wellness Center, and the Department of Family Medicine, University of Colorado Anschutz Medical Campus, Aurora; and the American Academy of Family Physicians National Research Network, Leawood, KS.
authors.forename: Nia S
authors.initials: NS
authors.lastname: Mitchell
authors.forename: Brian K
authors.initials: BK
authors.lastname: Manning
authors.forename: Elizabeth W
authors.initials: EW
authors.lastname: Staton
authors.forename: Caroline D
authors.initials: CD
authors.lastname: Emsermann
authors.forename: L Miriam
authors.initials: LM
authors.lastname: Dickinson
authors.forename: Wilson D
authors.initials: WD
authors.lastname: Pace
mesh_terms: D000328:Adult; D015415:Biomarkers; D001794:Blood Pressure; D015992:Body Mass Index; D004032:Diet; D015444:Exercise; D030141:Feedback, Psychological; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000523:psychology / Q000628:therapy*; D011788:Quality of Life; D015431:Weight Loss
chemical_list: D015415:Biomarkers; D008074:Lipoproteins
keywords: Diet; Exercise; Obesity; Practice-based Research