title: Hypothalamic hamartoma in an unusual case with delayed puberty.
abstract: Hypothalamic hamartoma (HH) is a rare intracranial lesion that usually presents with classic triad of central precocious puberty, gelastic epilepsy, and developmental delay. Herein, a 14-year old boy is presented in whom the diagnosis of HH was made by magnetic resonance imaging. While he did not have any complain of precocious puberty, he surprisingly suffered from delay in puberty. The definite diagnosis of HH can only be made by appropriate imaging, in a case with atypical feature of delay in puberty and in the absence of gelastic epilepsy. To our best knowledge, this is the first case of HH who is presented with delay in puberty as of first manifestation.
authors.affiliation: Research Center for Children and Adolescents Health, Zahedan University of Medical Sciences, Zahedan, Iran. rezaei_nima@tums.ac.ir.
authors.forename: Maryam
authors.initials: M
authors.lastname: Nakhaeimoghadam
authors.forename: Parastoo
authors.initials: P
authors.lastname: Rostami
authors.forename: Ameneh
authors.initials: A
authors.lastname: Zare-Shahabadi
authors.forename: Mehrzad
authors.initials: M
authors.lastname: Mehdizadeh
authors.forename: Ali
authors.initials: A
authors.lastname: Rabbani
authors.forename: Nima
authors.initials: N
authors.lastname: Rezaei
mesh_terms: D000293:Adolescent; D006222:Hamartoma / Q000175:diagnosis* / Q000503:physiopathology*; D006801:Humans; D007027:Hypothalamic Diseases / Q000175:diagnosis* / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D011628:Puberty, Delayed; D014057:Tomography, X-Ray Computed