title: Hydrodynamic particle focusing design using fluid-particle interaction.
abstract: For passive sheathless particles focusing in microfluidics, the equilibrium positions of particles are typically controlled by micro channels with a V-shaped obstacle array (VOA). The design of the obstacles is mainly based on the distribution of flow streamlines without considering the existence of particles. We report an experimentally verified particle trajectory simulation using the arbitrary Lagrangian-Eulerian (ALE) fluid-particle interaction method. The particle trajectory which is strongly influenced by the interaction between the particle and channel wall is systematically analyzed. The numerical experiments show that the streamline is a good approximation of particle trajectory only when the particle locates on the center of the channel in depth. As the advantage of fluid-particle interaction method is achieved at a high computational cost and the streamline analysis is complex, a heuristic dimensionless design objective based on the Faxen's law is proposed to optimize the VOA devices. The optimized performance of particle focusing is verified via the experiments and ALE method.
authors.affiliation: State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences, Changchun, Jilin, China ; University of Chinese Academy of Sciences, Beijing, China.
authors.forename: Teng
authors.initials: T
authors.lastname: Zhou
authors.affiliation: State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences, Changchun, Jilin, China.
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences, Changchun, Jilin, China.
authors.forename: Yihui
authors.initials: Y
authors.lastname: Wu
authors.affiliation: State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences, Changchun, Jilin, China.
authors.forename: Yongbo
authors.initials: Y
authors.lastname: Deng
authors.affiliation: State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences, Changchun, Jilin, China.
authors.forename: Yongshun
authors.initials: Y
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences, Changchun, Jilin, China ; University of Chinese Academy of Sciences, Beijing, China.
authors.forename: Geng
authors.initials: G
authors.lastname: Liu