title: Surface treatments of silver rods with enhanced iodide adsorption for I-125 brachytherapy seeds.
abstract: This study described an effective method to load (125)I on silver rods for the preparation of a brachytherapy source. We tested various ligands on the silver rod surface to screen the one with the highest adsorption and specific radioactivity. In addition, we investigated the effect of surface etching to increase the adsorption capability followed by the extended surface area. We also found that the use of an oxidant during iodide adsorption can increase the loading significantly. The maximum activity of 137.90MBq/rod (3.7269mCi/rod) was achieved on the etched silver rods with phosphate ligand and hydrogen peroxide as an oxidant. In addition, this is 4.5-fold higher than that of the conventional chloride treatment method.
authors.affiliation: Instrumental Analysis Laboratory, Department of Chemistry, Dongguk University, Seoul 100-715, Republic of Korea; Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600, Republic of Korea.
authors.forename: Jin Hee
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600, Republic of Korea.
authors.forename: Kang Hyuk
authors.initials: KH
authors.lastname: Choi
authors.affiliation: Instrumental Analysis Laboratory, Department of Chemistry, Dongguk University, Seoul 100-715, Republic of Korea. Electronic address: yukook@dongguk.edu.
authors.forename: Kook Hyun
authors.initials: KH
authors.lastname: Yu
mesh_terms: D000327:Adsorption; D001918:Brachytherapy / Q000379:methods*; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage*; D016877:Oxidants; D019275:Radiopharmaceuticals / Q000008:administration & dosage*; D012834:Silver; D013499:Surface Properties
chemical_list: D007457:Iodine Radioisotopes; D016877:Oxidants; D019275:Radiopharmaceuticals; D012834:Silver
keywords: Adsorption; Brachytherapy; I-125 seed; Iodine-125; Phosphate modification; Silver rod