title: Microbial production of 2,3-butanediol by a newly-isolated strain of Serratia marcescens.
abstract: A newly-isolated strain of Serratia marcescens, G12, was characterized for 2,3-butanediol (2,3-BD) production. In shake-flask and batch fermentations, 2,3-BD reached 48.5 and 51 g l(-1), respectively. Low amounts of (~8 g l(-1)) of acetoin were also formed. In fed-batch fermentations, strain G12 produced 72.8 g 2,3-BD l(-1) with glucose initially at 130 g l(-1). When aeration rate was increased to 2.5 vvm for the fermentation process, 2,3-BD reached 87.8 g l(-1) and the highest productivity was 1.6 g l(-1 )h(-1). Acetoin was at 6.2 g l(-1). G12 therefore may be a suitable candidate strain for large-scale production of 2,3-BD.
authors.affiliation: Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, China.
authors.forename: Litao
authors.initials: L
authors.lastname: Shi
authors.forename: Songsong
authors.initials: S
authors.lastname: Gao
authors.forename: Yue
authors.initials: Y
authors.lastname: Yu
authors.forename: Hongjiang
authors.initials: H
authors.lastname: Yang
mesh_terms: D000093:Acetoin / Q000032:analysis / Q000378:metabolism; D019149:Bioreactors / Q000382:microbiology*; D002072:Butylene Glycols / Q000032:analysis / Q000378:metabolism*; D005285:Fermentation; D012706:Serratia marcescens / Q000302:isolation & purification / Q000378:metabolism*
chemical_list: D002072:Butylene Glycols; C026978:2,3-butylene glycol; D000093:Acetoin