title: Chromatographic study on the high performance separation ability of a homochiral [Cu2(d-Cam)2(4,4'-bpy)]n based-column by using racemates and positional isomers as test probes.
abstract: This study focused on exploring the chromatographic characteristic of a homochiral MOF [Cu2(d-Cam)2(4,4'-bpy)]n with 3-D six-connected self-penetrating architectures for the separations of positional isomers and chiral compounds. Some effects such as mobile phase composition, column temperature, and analytes mass for separations on this chiral column also have been investigated. Among thirteen tested racemates, six compounds, namely three alcohols, a diol, a naphthol and a ketone were successfully discriminated, and ten useful positional isomers which have never been separated on other MOFs stationary phases in HPLC except dichlorobenzene and cresol isomers, were also analyzed by this chiral stationary phase. The results indicated that [Cu2(d-Cam)2(4,4'-bpy)]n exhibited good selectivity for positional isomers and enantiomers. Therefore, it is practicable that the separation of positional isomers and enantiomers are carried out on the chiral MOF column.
authors.affiliation: Department of Chemistry, East China Normal University, Shanghai 200241, PR China.
authors.forename: Mei
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Department of Chemistry, East China Normal University, Shanghai 200241, PR China.
authors.forename: Jun-Hui
authors.initials: JH
authors.lastname: Zhang
authors.affiliation: Department of Chemistry, Yunnan Normal University, Kunming 650500, PR China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Chemistry, Yunnan Normal University, Kunming 650500, PR China.
authors.forename: Bang-Jin
authors.initials: BJ
authors.lastname: Wang
authors.affiliation: Department of Chemistry, Yunnan Normal University, Kunming 650500, PR China.
authors.forename: Sheng-Ming
authors.initials: SM
authors.lastname: Xie
authors.affiliation: Department of Chemistry, East China Normal University, Shanghai 200241, PR China; Department of Chemistry, Yunnan Normal University, Kunming 650500, PR China. Electronic address: yuan_limingpd@aliyun.com.
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Yuan
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation* / Q000379:methods; D003300:Copper / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013816:Thermodynamics
chemical_list: D009942:Organometallic Compounds; D003300:Copper
keywords: Enantioseparation; High performance liquid chromatography; Homochiral metal-organic frameworks; Positional isomers separation.; Stationary phase