title: Fetal hypoplastic left heart syndrome and maternal liver transplantation for Wilson's disease: a case report.
abstract: BACKGROUND
  Liver transplantation currently represents the only curative treatment for Wilson's disease. A lifelong immunosuppressive therapy is mandatory. In spite of increased maternal and fetal risks, pregnancies after liver transplantation have been reported with favorable perinatal outcomes. Hypoplastic left heart syndrome is a spectrum of congenital heart defects that results in the inability to support the systemic circulation. Although its etiology remains elusive, the prognosis of this previously fatal condition has dramatically improved over the last 2 decades mainly due to advances in prenatal diagnosis, surgical technique and perioperative care.
  
  
  METHODS
  We present a case of a Caucasian 26-year-old woman, gravida 2, para 1 at 36+0 weeks of gestation who had received a liver transplantation due to Wilson's disease and subsequently delivered a child with hypoplastic left heart syndrome.
  
  
  CONCLUSIONS
  This coincidence of medical conditions has not been described in the literature so far and its implications for mother and child as well as the pathophysiological mechanisms are discussed on the basis of a literature review.
authors.affiliation: Department of Gynecology and Obstetrics, University Hospitals Schleswig-Holstein, Campus Kiel, Arnold-Heller Strasse 3, Building 24, 24105 Kiel, Germany. Antonia.wenners@uksh.de.
authors.forename: Antonia
authors.initials: A
authors.lastname: Wenners
authors.forename: Colin
authors.initials: C
authors.lastname: Petko
authors.forename: Constantin
authors.initials: C
authors.lastname: von Kaisenberg
authors.forename: Alexander
authors.initials: A
authors.lastname: Strauss
authors.forename: Christel
authors.initials: C
authors.lastname: Eckmann-Scholz
authors.forename: Ulrike
authors.initials: U
authors.lastname: Hoffmann
authors.forename: Walter
authors.initials: W
authors.lastname: Jonat
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Alkatout