title: MALAdaptive: do we avoid metformin unnecessarily?
abstract: Convention holds that the use of metformin is contraindicated in many patients secondary to concerns about lactic acidosis. However, current evidence suggests that metformin-associated lactic acidosis is at most idiosyncratic. Awareness of the current evidence should permit broader use of this valuable medication.
authors.affiliation: the Departments of Family Medicine and Clinical Pharmacy, West Virginia University, Charleston.
authors.forename: Chris
authors.initials: C
authors.lastname: Terpening
mesh_terms: D000140:Acidosis, Lactic / Q000139:chemically induced*; D000075202:Contraindications; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy; D006801:Humans; D007004:Hypoglycemic Agents / Q000097:blood; D008687:Metformin / Q000097:blood
chemical_list: D007004:Hypoglycemic Agents; D008687:Metformin
keywords: Diabetes Mellitus; Lactic Acidosis; Metformin