title: Quality of life in adolescents with obsessive-compulsive disorder.
abstract: OBJECTIVE
  To compare adolescents with and without obsessive-compulsive disorder (OCD) with regard to quality of life and to investigate the association between quality of life and clinical characteristics.
  
  
  METHODS
  Participants were recruited from an epidemiological study conducted at high schools in the city of Porto Alegre, southern Brazil. The sample comprised 75 adolescents with OCD and 150 without the disorder, aged between 14 and 18 years. Participants were assessed using the following instruments: Schedule for Affective Disorders and Schizophrenia for School Aged Children - Present and Lifetime Version (K-SADS-PL), Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), World Health Organization Quality of Life Assessment - Abbreviated Version (WHOQOL-BREF), Beck Anxiety Inventory (BAI), and Beck Depressive Inventory - II (BDI-II).
  
  
  RESULTS
  The two groups showed significant differences in relation to depression symptoms, anxiety symptoms, and quality of life (all domains), with a poorer performance among adolescents with OCD when compared to those without the disorder. Stepwise regression analysis revealed a significant association between BDI-II scores and quality of life, in all domains.
  
  
  CONCLUSIONS
  Our findings suggest that adolescents with OCD, especially those with depression symptoms, have a poorer quality of life when compared with adolescents without OCD.
authors.affiliation: Department of Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto AlegreRS, Brazil.
authors.forename: Analise de Souza
authors.initials: Ade S
authors.lastname: Vivan
authors.affiliation: School of Psychology, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto AlegreRS, Brazil.
authors.forename: Lidiane
authors.initials: L
authors.lastname: Rodrigues
authors.affiliation: School of Psychology, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto AlegreRS, Brazil.
authors.forename: Guilherme
authors.initials: G
authors.lastname: Wendt
authors.affiliation: Department of Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto AlegreRS, Brazil.
authors.forename: Mônica Giaretton
authors.initials: MG
authors.lastname: Bicca
authors.affiliation: Department of Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto AlegreRS, Brazil.
authors.forename: Aristides Volpato
authors.initials: AV
authors.lastname: Cordioli
mesh_terms: D000293:Adolescent; D001007:Anxiety / Q000175:diagnosis / Q000523:psychology*; D001938:Brazil; D016022:Case-Control Studies; D003863:Depression / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D012720:Severity of Illness Index; D012737:Sex Factors