title: [Granulosa cell tumor of the ovary: retrospective study of 17 cases].
abstract: Granulosa cell tumors of the ovary are rare tumor of ovary, included in the sex cord-stromal tumor category, hormone secreting. Seventeen patients with adult-type granulosa cell tumor were identified between 1995 and 2012. All have received surgical treatment first at stage I. Thirty-three percent of the patients relapsed with peritoneal nodules in 68% of the cases, treated surgically and sometimes with complementary therapies, such as chemotherapy, radiotherapy, hormonal treatment. Overall survival and recurrence-free survival were 100% and 58.3%, respectively at 10 years with median time to recurrence of 6 years (4-27). These tumors have therefore a good prognosis and require long-time follow-up. Finally, the prognostic factors of recurrence identified in the literature are FIGO stage, the presence of residual tumor and tumor size.
authors.affiliation: Département de chirurgie oncologique, institut de cancérologie de Lorraine, université de Lorraine, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France. Electronic address: laureemilie.rebstock@gmail.com.
authors.forename: L-E
authors.initials: LE
authors.lastname: Rebstock
authors.affiliation: Département de chirurgie oncologique, institut de cancérologie de Lorraine, université de Lorraine, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France.
authors.forename: L
authors.initials: L
authors.lastname: Leufflen
authors.affiliation: Service de biopathologie, unité d'anatomie pathologique, institut de cancérologie de Lorraine, université de Lorraine, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Leroux
authors.affiliation: Département de biostatistiques, institut de cancérologie de Lorraine, université de Lorraine, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France.
authors.forename: V
authors.initials: V
authors.lastname: Harter
authors.affiliation: Département de chirurgie oncologique, institut de cancérologie de Lorraine, université de Lorraine, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France.
authors.forename: J-L
authors.initials: JL
authors.lastname: Verhaeghe
authors.affiliation: Département de chirurgie oncologique, institut de cancérologie de Lorraine, université de Lorraine, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France; Département de chirurgie oncologique, institut de cancérologie de Lorraine, CRAN, UMR 7039, université de Lorraine, CNRS, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France.
authors.forename: F
authors.initials: F
authors.lastname: Marchal
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D006106:Granulosa Cell Tumor / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate
keywords: Facteurs pronostiques; Granulosa cell tumors; Prognostic factors; Recurrence; Récidive; Tumeur de la Granulosa