title: Liquid and back gate coupling effect: toward biosensing with lowest detection limit.
abstract: We employ noise spectroscopy and transconductance measurements to establish the optimal regimes of operation for our fabricated silicon nanowire field-effect transistors (Si NW FETs) sensors. A strong coupling between the liquid gate and back gate (the substrate) has been revealed and used for optimization of signal-to-noise ratio in subthreshold as well as above-threshold regimes. Increasing the sensitivity of Si NW FET sensors above the detection limit has been predicted and proven by direct experimental measurements.
authors.affiliation: Peter Grünberg Institute (PGI-8) , Forschungszentrum Jülich, Jülich 52425, Germany.
authors.forename: Sergii
authors.initials: S
authors.lastname: Pud
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Volodymyr
authors.initials: V
authors.lastname: Sibiliev
authors.forename: Mykhaylo
authors.initials: M
authors.lastname: Petrychuk
authors.forename: Valery
authors.initials: V
authors.lastname: Kovalenko
authors.forename: Andreas
authors.initials: A
authors.lastname: Offenhäusser
authors.forename: Svetlana
authors.initials: S
authors.lastname: Vitusevich
mesh_terms: D001704:Biopolymers / Q000032:analysis* / Q000737:chemistry; D015374:Biosensing Techniques / Q000295:instrumentation*; D003217:Conductometry / Q000295:instrumentation*; D004566:Electrodes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008832:Microchemistry / Q000295:instrumentation; D053770:Nanowires / Q000737:chemistry* / Q000648:ultrastructure; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D059629:Signal-To-Noise Ratio; D012996:Solutions; D014173:Transistors, Electronic
chemical_list: D001704:Biopolymers; D012996:Solutions