title: Midterm results of bovine jugular vein conduit for right ventricular outflow tract reconstruction.
abstract: OBJECTIVE
  To evaluate the midterm results of Contegra conduit.
  
  
  METHODS
  The retrospective study comprised patient record at Aga Khan University Hospital, Karachi, of conduits implanted between May 2007 and June 2012. Data collection was made from the clinical notes and from serial echocardiograms by a single cardiologist. The last followup echocardiography was done at the time of data collection in June 2012. SPSS 19 was used for statistical analysis.
  
  
  RESULTS
  A total of 18 conduits had been implanted (16-22 mm) during the study period. Median age at the time of surgery was 9 years (range: 2.5-16 years). Early mortality was seen in 3 (16.66%) patients, but none was Contegra related. Of the remaining 15 patients, 2 (13.33%) with a diagnosis of Pulmonary Atresia-Ventricular Septal Defect with hypoplastic peripheral Pulmonary Arteries (PA), developed severe distal pressure gradient (50 mmHg) across Contegra over a median period of 18 months (range: 12-24 months), with resultant severe regurgitation and needed percutaneous intervention. There was no thrombosis, calcification, anuerysmal dilation or late deaths.
  
  
  CONCLUSIONS
  At midterm followup, Contegra conduit was associated with low re-intervention rates with satisfactory haemodynamic results. However, long-term durability must be determined for this conduit, especially in patients with Pulmonary Atresia-Ventricular Septal Defect with hypoplastic peripheral Pulmonary Arteries.
authors.affiliation: Department of Pediatrics and Child Health, Aga Khan University Hospital. shzsmd@yahoo.com
authors.forename: Shazia Samad
authors.initials: SS
authors.lastname: Mohsin
authors.affiliation: Liaquat National Hospital and Medical College, University of Karachi.
authors.forename: Maria Tariq
authors.initials: MT
authors.lastname: Siddiqui
authors.affiliation: Department of Pediatrics and Child Health, Aga Khan University Hospital.
authors.forename: Abdul Sattar
authors.initials: AS
authors.lastname: Shaikh
authors.affiliation: Department of Pediatrics and Child Health, Aga Khan University Hospital.
authors.forename: Mehnaz
authors.initials: M
authors.lastname: Atiq
authors.affiliation: Department of Cardiothoracic Surgery, Aga Khan University Hospital.
authors.forename: Muneer
authors.initials: M
authors.lastname: Amanullah
mesh_terms: D000293:Adolescent; D001807:Blood Vessel Prosthesis; D002648:Child; D002675:Child, Preschool; D005260:Female; D006330:Heart Defects, Congenital / Q000601:surgery*; D006350:Heart Valve Prosthesis; D006801:Humans; D007601:Jugular Veins / Q000637:transplantation*; D008297:Male; D019651:Plastic Surgery Procedures; D012189:Retrospective Studies; D016896:Treatment Outcome; D014694:Ventricular Outflow Obstruction / Q000209:etiology / Q000601:surgery*