title: Gyrification differences in children and adolescents with velocardiofacial syndrome and attention-deficit/hyperactivity disorder: a pilot study.
abstract: We used magnetic resonance imaging to investigate brain gyrification patterns between 19 children with attention-deficit/hyperactivity disorder (ADHD), 9 children with velocardiofacial syndrome (VCFS), and 23 control children. We found that VCFS is associated with widespread decreases in gyrification. In ADHD, we found minor differences from control children. No evidence was found for common gyrification patterns between VCFS and ADHD children.
authors.affiliation: Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC Rotterdam, The Netherlands; The Generation R Study Group, Erasmus MC Rotterdam, The Netherlands.
authors.forename: Sabine E
authors.initials: SE
authors.lastname: Mous
authors.affiliation: Institute of Child Development, University of Minnesota, Minneapolis, MN, USA.
authors.forename: Canan
authors.initials: C
authors.lastname: Karatekin
authors.affiliation: Department of Mathematics, The Ohio State University, Columbus, OH, USA; Department of Mathematical Sciences, Claremont McKenna College, Claremont, CA, USA.
authors.forename: Chiu-Yen
authors.initials: CY
authors.lastname: Kao
authors.affiliation: Department of Psychology, University of Minnesota, Minneapolis, MN, USA.
authors.forename: Irving I
authors.initials: II
authors.lastname: Gottesman
authors.affiliation: Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC Rotterdam, The Netherlands; Center for Neurogenomics and Cognitive Research, Complex Traits Genetics, VU Amsterdam, The Netherlands; Department of Clinical Genetics, Section on Medical Genomics, VU Medical Centre, Amsterdam, The Netherlands.
authors.forename: Danielle
authors.initials: D
authors.lastname: Posthuma
authors.affiliation: Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC Rotterdam, The Netherlands; Department of Radiology, Erasmus MC Rotterdam, The Netherlands. Electronic address: t.white@erasmusmc.nl.
authors.forename: Tonya
authors.initials: T
authors.lastname: White
mesh_terms: D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications / Q000473:pathology*; D016022:Case-Control Studies; D002540:Cerebral Cortex / Q000002:abnormalities / Q000473:pathology*; D002648:Child; D004062:DiGeorge Syndrome / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010865:Pilot Projects; D055815:Young Adult
keywords: Attention-deficit/hyperactivity disorder (ADHD); Brain gyrification; Velocardiofacial syndrome (VCFS)