title: Retinal nerve fiber layer thickness in women with polycystic ovary syndrome.
abstract: Aim. To compare the retinal nerve fiber layer (RNFL) thickness between women with polycystic ovary syndrome (PCOS) and healthy women. Materials and Methods. The study included 88 eyes of 44 women (group 1) with PCOS and 84 eyes of 42 healthy women (group 2). In all subjects, the RNFL and ganglion cell complex (GCC) thicknesses were measured by optical coherence tomography (OCT). In addition, visual acuity (VA), intraocular pressure (IOP), refractive errors, central macular thickness (CMT), central corneal thickness (CCT), and excavation of optic disc were evaluated in all subjects. Results. Mean values of GCC, IOP, VA, CMT, CCT, and refractive errors were similar between the 2 groups. The average RNFL, superior average RNFL, and inferior average RNFL thicknesses were higher in subjects with PCOS than in healthy subjects (P = 0.003, P = 0.012, and P = 0.009), respectively. Conclusion. The average RNFL, superior average RNFL, and inferior average RNFL thicknesses in women with PCOS were significantly higher than in healthy women.
authors.affiliation: Department of Ophthalmology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Demir
authors.affiliation: Department of Ophthalmology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, Turkey.
authors.forename: Dilek
authors.initials: D
authors.lastname: Guven
authors.affiliation: Department of Obstetrics and Gynecology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Koc
authors.affiliation: Department of Obstetrics and Gynecology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, Turkey.
authors.forename: Savas
authors.initials: S
authors.lastname: Ozdemir
authors.affiliation: Department of Ophthalmology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, Turkey.
authors.forename: Efe
authors.initials: E
authors.lastname: Can