title: Complication of diagnostic pleural aspiration: is it of value in hemodialysis patients?
abstract: Pleural effusions are common in hemodialysis patients and are associated with significant morbidity. Diagnostic pleural aspiration and subsequent biochemical analysis can be used to differentiate exudates and transudates. In particular, Light's criteria have been validated in the general population although their efficacy in hemodialysis patients is unclear. Furthermore, aspiration is not without risk; we report the case of a life-threatening thoracic bleed as a complication of diagnostic thoracocentesis in a hemodialysis patient, in whom a transudative effusion was misclassified according to Light's criteria. Retrospective examination of a further 22 aspirations in hemodialysis patients suggests that biochemical analysis of pleural fluid in this group is of limited value. Careful clinical and radiological assessment may be of greater value in determining individuals who may benefit from formal drainage, rather than diagnostic aspiration with its attendant risks.
authors.affiliation: Imperial College and Renal Transplant Centre, Imperial College Healthcare NHS Trust, London, UK.
authors.forename: Richard W
authors.initials: RW
authors.lastname: Corbett
authors.forename: Damien R
authors.initials: DR
authors.lastname: Ashby
mesh_terms: D000368:Aged; D006801:Humans; D007676:Kidney Failure, Chronic / Q000473:pathology / Q000628:therapy*; D008297:Male; D010996:Pleural Effusion / Q000175:diagnosis* / Q000473:pathology; D006435:Renal Dialysis / Q000009:adverse effects / Q000379:methods*
keywords: Hemodialysis; Light's criteria; bleeding; pleural effusion; thoracocentesis