title: [Analysis of measles immunity level in persistent populations in Beijing, 2012].
abstract: OBJECTIVE
  To analyze the measles immunity level of persistent population in Beijing.
  
  
  METHODS
  A total of 2125 objects from 10 age groups, who had been living in Beijing for over 6 months, were selected from urban and rural areas in Beijing in 2012. Demographic characteristics, history of measles and vaccine immunization were investigated by questionnaire. 5 ml blood sample of each subject was collected, and the Measles IgG antibody was measured by ELISA assay.
  
  
  RESULTS
  Positive rate of measles antibody was 84.71% (1800/2125) and standardized positive rate was 88.07% . Median of antibody was 960.46 IU/L. Positive rate and median of measles antibody were significantly different between population from different age groups (χ(2) = 341.60, P < 0.01; H = 216.27, P < 0.01). Antibody positive rate and median were lowest in the <1 year age group, which were separately 43.06% (90/209) and 185.80 IU/L; and highest in the 1-4 (97.31% (181/186) and 2448.81 IU/L) and 5-9 years age group (96.46% (218/226) and 1910.72 IU/L). The range of antibody positive rate and median in adults of ≥ 15 years were 81.98%-90.14% and 744.38-1474.84 IU/L. Antibody positive rate and median in persistent population, which were separately 82.45% (883/1071) and 899.82 IU/L, were lower than those in migrant population, which were 87.00% (917/1054) and 166.19 IU/L, respectively (χ(2) = 8.51, P < 0.01;U = 538 704.00, P < 0.01). Antibody positive rate and median in population with vaccination history, which were separately 91.95% (891/969) and 1443.11 IU/L, were higher than those population without vaccination history and people whose history unknown (32.95% (57/173) , 127.33 IU/L; 86.67% (852/983) , 923.73 IU/L). The difference showed statistical significance (χ(2) = 399.92, P < 0.01; H = 202.11, P < 0.01).
  
  
  CONCLUSIONS
  Among the persistent population in China, measles antibody level among the children aging 1-9 years old was high enough to prevent outbreak and epidemic of measles. However, we should try our best to strengthen the measles antibody level among the babies younger than 1 year old and the migrant population aging between 15 and 40 years old.
authors.affiliation: Beijing Center for Disease Control and Prevention,Beijing 100013, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Li
authors.forename: Li
authors.initials: L
authors.lastname: Lu
authors.forename: Meng
authors.initials: M
authors.lastname: Chen
authors.forename: Fang
authors.initials: F
authors.lastname: Huang
authors.forename: Yang
authors.initials: Y
authors.lastname: Zeng
authors.forename: Xiao-mei
authors.initials: XM
authors.lastname: Li
authors.forename: Rui
authors.initials: R
authors.lastname: Ma
authors.forename: Jing-bin
authors.initials: JB
authors.lastname: Pan
authors.forename: Mu
authors.initials: M
authors.lastname: Sun
authors.forename: Hao
authors.initials: H
authors.lastname: Sun
authors.forename: Zhong-zhan
authors.initials: ZZ
authors.lastname: Wang
authors.forename: Fang-ru
authors.initials: FR
authors.lastname: Guo
authors.forename: Yi-hua
authors.initials: YH
authors.lastname: Zhang
authors.forename: Feng-shuang
authors.initials: FS
authors.lastname: Wang
authors.forename: Tao
authors.initials: T
authors.lastname: Wu
authors.forename: De-jun
authors.initials: DJ
authors.lastname: Cui
authors.forename: Xing-hui
authors.initials: XH
authors.lastname: Peng
authors.affiliation: Email:wujiang@bjcdc.org.
authors.forename: Jiang
authors.initials: J
authors.lastname: Wu
authors.forename: Xing-huo
authors.initials: XH
authors.lastname: Pang
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008457:Measles / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D008459:Measles virus; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral