title: The overpowered mega-study is a new class of study needing a new way of being reviewed.
authors.affiliation: University of Iowa, Iowa City, Iowa (R.M.R.). rob-raw@uiowa.edu.
authors.forename: Robert M
authors.initials: RM
authors.lastname: Raw
authors.forename: Michael M
authors.initials: MM
authors.lastname: Todd
authors.forename: Brad J
authors.initials: BJ
authors.lastname: Hindman
authors.forename: Rashmi
authors.initials: R
authors.lastname: Mueller
mesh_terms: D000768:Anesthesia, General; D005260:Female; D006801:Humans; D008297:Male; D019637:Orthopedic Procedures / Q000379:methods*; D019990:Perioperative Care / Q000379:methods*