title: Ultrasensitive online SERS detection of structural isomers separated by capillary zone electrophoresis.
abstract: A mixture of structural isomers was separated and identified at nanomolar concentrations (∼100,000 molecules) by incorporating capillary zone electrophoresis (CZE) with a sheath flow surface-enhanced Raman scattering (SERS) detector. Baseline resolution was obtained from three structural isomers of rhodamine using a planar silver SERS substrate, demonstrating the utility of this approach for trace chemical analysis.
authors.affiliation: Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA. Schultz.41@nd.edu.
authors.forename: Pierre
authors.initials: P
authors.lastname: Negri
authors.forename: Ryan J
authors.initials: RJ
authors.lastname: Flaherty
authors.forename: Oluwatosin O
authors.initials: OO
authors.lastname: Dada
authors.forename: Zachary D
authors.initials: ZD
authors.lastname: Schultz
mesh_terms: D004396:Coloring Agents / Q000032:analysis* / Q000737:chemistry; D019075:Electrophoresis, Capillary; D007536:Isomerism; D012235:Rhodamines / Q000032:analysis* / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D013059:Spectrum Analysis, Raman
chemical_list: D004396:Coloring Agents; D012235:Rhodamines; D012834:Silver