title: Comparison of desensitizing efficacy of an Iranian dentifrice and a commercially available dentifrice: a randomized double-blinded controlled clinical trial.
abstract: OBJECTIVE
  The aim of this randomized controlled clinical trial was to investigate the effect of a new Iranian toothpaste and a commercially available toothpaste containing desensitizing agent (5% potassium nitrate) on dentine hypersensitivity in a 24-week study.
  
  
  METHODS
  Fifty healthy volunteers, who had at least two sensitive root surfaces, completed the study period. The participants were randomly given one of the two toothpastes; Iranian (antihypersensitive Pooneh) or commercially available (fresh mint Sensodyne) toothpaste. Visual analogue scales (VASs) indicating the intensity of tooth hypersensitivity responding to tactile, airblast and cold-water stimuli were examined at baseline and weeks 2, 4, 12 and 24.
  
  
  RESULTS
  Overall, VAS scores for tactile, airblast, and cold-water tests significantly reduced compared with the baseline in both groups (all P values <0.001). However, there was no significant difference between the two groups regarding the measured parameters.
  
  
  CONCLUSIONS
  This study demonstrated that the Iranian dentifrice (antihypersensitive Pooneh) was as effective as the commercially available one (fresh mint Sensodyne) in reducing tooth hypersensitivity.
authors.affiliation: Laser Research Center in Dentistry, Tehran University of Medical Sciences, Tehran, Iran ; Assistant Professor, Department of Periodontics, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Neda
authors.initials: N
authors.lastname: Moslemi
authors.affiliation: Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Johari
authors.affiliation: Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran ; Professor, Department of Orthodontic, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad Sadegh Ahmad
authors.initials: MS
authors.lastname: Akhoundi
authors.affiliation: Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Hadi
authors.initials: H
authors.lastname: Zare
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Ahmad-Reza
authors.initials: AR
authors.lastname: Shamshiri
authors.affiliation: Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Azam
authors.initials: A
authors.lastname: Khorshidian
keywords: Clinical Trial; Dentin Hypersensitivity; Potassium Nitrate; Toothpaste