title: Large vessel vasculitis with myelodysplastic syndrome.
abstract: A 71-year-old woman presented with a high-grade fever, neck pain, anemia and thrombocytopenia. After performing further examinations, we concluded that she had simultaneously developed large vessel vasculitis and myelodysplastic syndrome (MDS). Although glucocorticoid administration improved her clinical symptoms, the MDS transformed into acute myeloid leukemia and she died one year after receiving the diagnosis. The occurrence of immune-mediated disorders in patients with MDS is a well-known phenomenon; however, large vessel vasculitis is a rare complication of MDS. Our case suggests that the association between systemic vasculitis and MDS may result in poor outcomes.
authors.affiliation: Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Katsuyama
authors.forename: Haruhito Adam
authors.initials: HA
authors.lastname: Uchida
authors.forename: Kishio
authors.initials: K
authors.lastname: Toma
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Maeda
authors.forename: Daisho
authors.initials: D
authors.lastname: Hirota
authors.forename: Ryoko
authors.initials: R
authors.lastname: Umebayashi
authors.forename: Ken-Ei
authors.initials: KE
authors.lastname: Sada
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Makino
mesh_terms: D000368:Aged; D001167:Arteritis / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000175:diagnosis*; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis