title: Rhodium-catalyzed chemo- and regioselective decarboxylative addition of β-ketoacids to allenes: efficient construction of tertiary and quaternary carbon centers.
abstract: A rhodium-catalyzed chemo- and regioselective intermolecular decarboxylative addition of β-ketoacids to terminal allenes is reported. Using a Rh(I)/DPPF system, tertiary and quaternary carbon centers were formed with exclusively branched selectivity under mild conditions. Preliminary mechanism studies support that the carbon-carbon bond formation precedes the decarboxylation and the reaction occurs in an outer-sphere mechanism.
authors.affiliation: Institut für Organische Chemie, Albert-Ludwigs-Universität Freiburg , Albertstrasse 21, 79104 Freiburg im Breisgau, Germany.
authors.forename: Changkun
authors.initials: C
authors.lastname: Li
authors.forename: Bernhard
authors.initials: B
authors.lastname: Breit