title: Management of neurogenic orthostatic hypotension.
abstract: The burden of orthostatic hypotension (OH) on public health is a universally recognized enigmatic clinical condition that is associated with significant increases on morbidity and mortality rates, and can take a major toll on one's quality of life. Orthostatic hypotension is predictive of vascular deaths from acute myocardial infarction, strokes in the middle aged population, and increases mortality rates when associated with diabetes, hypertension, Parkinson's disease, and patients receiving renal dialysis. The consensus definition for OH is a fall in systolic blood pressure of at least 20 mm Hg and/or diastolic blood pressure of at least 10 mm Hg within 3 minutes of quiet standing. Because neurogenic OH is often accompanied by supine hypertension, the treatment program should aim toward minimizing OH and the potential fall injuries related to cerebral hypoperfusion without exacerbating nocturnal hypertension that may lead to excessive cardiovascular complications.
authors.affiliation: UT Southwestern Medical Center at Dallas, Internal Medicine, Cardiology Division: Hypertension Section, Dallas, TX.
authors.forename: Debbie
authors.initials: D
authors.lastname: Arbique
authors.affiliation: Harris College of Nursing and Health Sciences and School of Nurse Anesthesia, Texas Christian University, Fort Worth, TX.
authors.forename: Dennis
authors.initials: D
authors.lastname: Cheek
authors.affiliation: Harris College of Nursing and Health Sciences and School of Nurse Anesthesia, Texas Christian University, Fort Worth, TX.
authors.forename: Mark
authors.initials: M
authors.lastname: Welliver
authors.affiliation: UT Southwestern Medical Center at Dallas, Internal Medicine, Cardiology Division: Hypertension Section, Dallas, TX. Electronic address: wanpen.vongpatanasin@utsouthwestern.edu.
authors.forename: Wanpen
authors.initials: W
authors.lastname: Vongpatanasin
mesh_terms: D000328:Adult; D005260:Female; D006358:Hot Temperature / Q000009:adverse effects; D006801:Humans; D007024:Hypotension, Orthostatic / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*
chemical_list: D014662:Vasoconstrictor Agents
keywords: Neurogenic orthostatic hypotension; diagnostic tests; morbidity; mortality; neurogenic; pharmacological and nonpharmacological; physiology and pathophysiology with standing; supine hypertension