title: Impact of a chromosome X STR Decaplex in deficiency paternity cases.
abstract: Deficiency paternity cases, characterized by the absence of the alleged father, are a challenge for forensic genetics. Here we present four cases with a female child and a deceased alleged father in which the analysis of a set of 21 or 22 autosomal STRs (AS STRs) produced results within a range of doubt when genotyping relatives of the alleged father. Aiming to increase the Paternity Index (PI) and obtain more reliable results, a set of 10 X-linked STR markers, developed by the Spanish and Portuguese Group of the International Society for Forensic Genetics (ISFG), was then added. Statistical analysis substantially shifted the results towards the alleged fatherhood in all four cases, with more dramatic changes when the supposed half-sister and respective mother were the relatives tested.
authors.affiliation: Laboratório de Antropologia Forense, Instituto de Medicina Legal, Polícia Civil do Distrito Federal, Brasília, DF, Brazil . ; Programa de Pós-Graduação em Ciências da Saúde, Faculdade de Ciências da Saúde, Universidade de Brasília, Brasília, DF, Brazil .
authors.forename: Aluisio
authors.initials: A
authors.lastname: Trindade-Filho
authors.affiliation: Instituto de Pesquisa de DNA Forense, Polícia Civil do Distrito Federal, Brasília, DF, Brazil .
authors.forename: Samuel
authors.initials: S
authors.lastname: Ferreira
authors.affiliation: Programa de Pós-Graduação em Ciências da Saúde, Faculdade de Ciências da Saúde, Universidade de Brasília, Brasília, DF, Brazil . ; Laboratório de Genética, Departamento de Genética e Morfologia, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, DF, Brazil .
authors.forename: Silviene F
authors.initials: SF
authors.lastname: Oliveira
keywords: ChrX STR Decaplex; Paternity Index; X-linked markers; deficiency paternity case; forensic genetics