title: Intramesenteric steroid treatment for steroid- refractory gastrointestinal graft versus host disease.
abstract: Currently, steroid-refractory severe gastrointestinal (GI) graft versus host disease (GVHD) is among the most important complications of allogeneic transplantation, and as yet there is no standard approach to its treatment. Herein we report two cases with steroid-refractory GI GVHD that received intramesenteric steroid treatment. In both cases the frequency and volume of diarrhea resolved completely following intramesenteric methylprednisolone (MP) injection. In conclusion, intra-arterial steroid injection might be an alternative treatment approach for steroid-refractory GI GVHD.
  
  
  BACKGROUND
  None declared.
authors.affiliation: Necmettin Erbakan University, Meram Faculty of Medicine, Division of Hematology, Department of Internal Medicine, Konya, Turkey.
authors.forename: Aynur Uğur
authors.initials: AU
authors.lastname: Bilgin
authors.affiliation: Ankara University, School of Medicine, Division of Hematology, Department of Internal Medicine, Ankara, Turkey.
authors.forename: Pervin
authors.initials: P
authors.lastname: Topcuoğlu
authors.affiliation: Ankara University, School of Medicine, Division of Radiology, Ankara, Turkey.
authors.forename: Tanzer
authors.initials: T
authors.lastname: Sancak
authors.affiliation: Ankara University, School of Medicine, Division of Hematology, Department of Internal Medicine, Ankara, Turkey.
authors.forename: Nahide
authors.initials: N
authors.lastname: Konuk
authors.affiliation: Ankara University, School of Medicine, Division of Hematology, Department of Internal Medicine, Ankara, Turkey.
authors.forename: Mutlu
authors.initials: M
authors.lastname: Arat
keywords: Intramesenteric steroid; Steroid-refractory GVHD