title: Application of a subcutaneous negative pressure drain without subcutaneous suture: impact on wound healing in gynecologic surgery.
abstract: OBJECTIVE
  To evaluate the surgical outcome of a subcutaneous negative pressure drain without subcutaneous suture on wound healing in women undergoing abdominal gynecologic surgery.
  
  
  METHODS
  The medical records of total 322 patients who underwent abdominal surgery, including cytoreductive surgery for ovarian cancer, between March 2010 and January 2013 were reviewed retrospectively. Patients were divided into two groups by the presence of subcutaneous negative pressure drains without subcutaneous suture, or suture without drainage.
  
  
  RESULTS
  Patient's characteristics in the two groups were not statistically different. Among all patients, the 71 patients who had a subcutaneous wound drain achieved a higher rate of clear healing (97.2% vs. 88.8%; p=0.033): 100% vs. 98.0% (not significant) in 126 benign and 95.6% vs. 82.8% (p=0.032) in 196 malignant disease patients. In a multivariate analysis, wound drain placement was an independent prognostic factor affecting the surgical wound outcome; the disruption (OR, 0.100; 95% CI, 0.021-0.485; p=0.004) rate was significantly lower with subcutaneous negative pressure drain. Placement of a subcutaneous negative pressure drain without subcutaneous suture resulted in clinical benefit, such as shorter admission duration (median, 8 vs. 11 days; p=0.021).
  
  
  CONCLUSIONS
  Application of subcutaneous negative pressure drain is one of the effective and easy ways for clearer wound healing after major gynecologic surgery for malignant disease.
authors.affiliation: Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Gyeonggi-do, Republic of Korea; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.
authors.forename: Se Ik
authors.initials: SI
authors.lastname: Kim
authors.affiliation: Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Gyeonggi-do, Republic of Korea; Gynecologic Cancer Branch, Research Institute and Hospital, National Cancer Center, Gyeonggi-do, Republic of Korea. Electronic address: mclim@ncc.re.kr.
authors.forename: Myong Cheol
authors.initials: MC
authors.lastname: Lim
authors.affiliation: Department of Obstetrics and Gynecology, Pusan National University Yangsan Hospital, Gyeongsangnam-do, Republic of Korea; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Gyeongsangnam-do, Republic of Korea. Electronic address: gynsong@gmail.com.
authors.forename: Yong Jung
authors.initials: YJ
authors.lastname: Song
authors.affiliation: Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Gyeonggi-do, Republic of Korea.
authors.forename: Sang-Soo
authors.initials: SS
authors.lastname: Seo
authors.affiliation: Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Gyeonggi-do, Republic of Korea; Gynecologic Cancer Branch, Research Institute and Hospital, National Cancer Center, Gyeonggi-do, Republic of Korea.
authors.forename: Sokbom
authors.initials: S
authors.lastname: Kang
authors.affiliation: Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Gyeonggi-do, Republic of Korea; Gynecologic Cancer Branch, Research Institute and Hospital, National Cancer Center, Gyeonggi-do, Republic of Korea.
authors.forename: Sang-Yoon
authors.initials: SY
authors.lastname: Park
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D004322:Drainage / Q000379:methods; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy; D013530:Surgical Wound Infection / Q000517:prevention & control*; D013537:Sutures; D014945:Wound Healing / Q000502:physiology*; D055815:Young Adult
keywords: Subcutaneous drain; Surgical site infection; Wound complications