title: Novel ionophores with 2n-crown-n topology: anion sensing via pure aliphatic C-H···anion hydrogen bonding.
abstract: A series of novel coronands having a 2n-crown-n topology based on trioxane (6-crown-3) derivatives are designed and characterized. These neutral hosts can sense anions through pure aliphatic C-H hydrogen bonding (HB) in condensed phases due to the unusual topology of 2n-crown-n. C-H bonds are strongly polarized by two adjacent oxygen atoms in this scaffold. These hosts provide a rare opportunity to modulate anion binding strength by changing the electronic nature of aliphatic C-H bonds and offer ease of synthesis.
authors.affiliation: Department of Chemistry, Pohang University of Science and Technology , Pohang, 790-784, Republic of Korea.
authors.forename: Genggongwo
authors.initials: G
authors.lastname: Shi
authors.forename: Changdev G
authors.initials: CG
authors.lastname: Gadhe
authors.forename: Sung-Woo
authors.initials: SW
authors.lastname: Park
authors.forename: Kwang S
authors.initials: KS
authors.lastname: Kim
authors.forename: Jongmin
authors.initials: J
authors.lastname: Kang
authors.forename: Humaira
authors.initials: H
authors.lastname: Seema
authors.forename: N Jiten
authors.initials: NJ
authors.lastname: Singh
authors.forename: Seung Joo
authors.initials: SJ
authors.lastname: Cho
mesh_terms: D000838:Anions; D043844:Crown Ethers / Q000138:chemical synthesis / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006859:Hydrogen; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000838:Anions; D043844:Crown Ethers; D006859:Hydrogen