title: A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells.
abstract: A novel near-infrared (NIR) and colorimetric fluorescent molecular probe based on a dicyanomethylene-4H-pyran chromophore for the selective detection of glutathione in living cells has been developed. The fluorescence OFF-ON switch is triggered by cleavage of the 2,4-dinitrobenzensulfonyl (DNBS) unit by the interaction with GSH.
authors.affiliation: Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK. t.d.james@bath.ac.uk.
authors.forename: Meng
authors.initials: M
authors.lastname: Li
authors.forename: Xumeng
authors.initials: X
authors.lastname: Wu
authors.forename: Yao
authors.initials: Y
authors.lastname: Wang
authors.forename: Yongsheng
authors.initials: Y
authors.lastname: Li
authors.forename: Weihong
authors.initials: W
authors.lastname: Zhu
authors.forename: Tony D
authors.initials: TD
authors.lastname: James
mesh_terms: D002470:Cell Survival; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D003124:Colorimetry; D005978:Glutathione / Q000032:analysis* / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D007259:Infrared Rays; D013050:Spectrometry, Fluorescence
chemical_list: D005978:Glutathione