title: [Cardiovascular disease risk and vascular damage status in pre- and hypertension population in coastal areas of Fujian province].
abstract: OBJECTIVE
  To observe the cardiovascular risk factors and vascular damage status of pre- and hypertensive population in the coastal areas of Fujian province.
  
  
  METHODS
  This cross-sectional study surved 3344 Fujian coastal people aged older than 30 years. Glycolipids, uric acid, urine, microalbumin, brachial-ankle pulse wave velocity(baPWV) and central retinal arteriolar equivalent(CRAE) measurements were performed. Variance analysis and binary logistic regression were applied to evaluate cardiovascular risk factors and vascular damage of prehypertensive as well as hypertensive population.
  
  
  RESULTS
  (1) The morbidity of prehypertension as well as hypertension was 30.0% in coastal population of Fujian Province, there were more than 3 cardiovascular risk factors in 65.5% (909/1388) of the hypertensive population and 37.5% of the prehypertensive population.(2) The abnormal rates of creatinine ratio(UACR), baPWV, and CRAE in hypertensive [25.7% (357/1388) , 84.2% (1169/1388) , 29.5% (409/1388) ] and prehypertensive population [20.0% (176/880) , 29.1% (256/880) , 25.6% (225/880)] were significantly higher than those of normotensive individuals [8.5% (91/1076), 8.9% (96/1076), 18.8% (202/1076), all P < 0.05].(3) Prehypertension and hypertension served as independent risk factors of UACR, baPWV and CRAE according to logistic regression analysis. The odds ratios (OR) value and 95% confidence intervals were 1.496 (1.095-2.044) , 2.477 (1.815-3.381) , 0.700 (0.549-0.891) in prehypertensive population, and 1.976 (1.454-2.686) , 7.707 (12.938-24.235) , 0.591 (0.474-0.736) in hypertensive population.
  
  
  CONCLUSIONS
  Multiple cardiovascular risk factors coexist in prehypertensive and hypertensive population in the coastal area of coastal areas of Fujian province and there is more morbidity of vascular damage in prehypertensive and hypertensive individuals compared to normotensive subjects in these areas.
authors.affiliation: Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Institute of Clinical Geriatrics, Provincial Clinical Medical College of Fujian Medical University, Fuzhou 350000, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Huang
authors.affiliation: Email: zpl7755@gmail.com.
authors.forename: Peng-li
authors.initials: PL
authors.lastname: Zhu
authors.forename: Hua-zhen
authors.initials: HZ
authors.lastname: Xiao
authors.forename: Fan
authors.initials: F
authors.lastname: Lin
authors.forename: Yin
authors.initials: Y
authors.lastname: Yuan
authors.forename: Zhong-hai
authors.initials: ZH
authors.lastname: Gao
authors.forename: Jian-wei
authors.initials: JW
authors.lastname: Li
authors.forename: Fa-lin
authors.initials: FL
authors.lastname: Chen
mesh_terms: D000368:Aged; D055109:Ankle Brachial Index; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000150:complications* / Q000503:physiopathology; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000503:physiopathology*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D058246:Prehypertension / Q000453:epidemiology* / Q000503:physiopathology*; D012307:Risk Factors