title: Tocolysis for preterm labor: expert opinion.
abstract: Tocolysis is an important treatment in the improvement of outcome in preterm labor and preterm birth, provided that its use follows clear evidence-based recommendations. In this expert opinion, the most recent evidence about efficacy and side effects of different tocolytics is being reviewed and evidence-based recommendation about diagnosis and treatment of preterm labor is given. Further aspects such as progesterone administration or antibiotic treatment for the prevention of preterm birth are included. Our review demonstrates that an individualized choice of different tocolytics and additional treatments is necessary to improve short- and long-term neonatal outcome in preterm labor and preterm birth.
authors.affiliation: Committee for Quality Assurance, Swiss Society of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, University Hospital Inselspital, Effingerstrasse 102, 3010, Bern, Switzerland.
authors.forename: Irène
authors.initials: I
authors.lastname: Hösli
authors.forename: Christiane
authors.initials: C
authors.lastname: Sperschneider
authors.forename: Gero
authors.initials: G
authors.lastname: Drack
authors.forename: Roland
authors.initials: R
authors.lastname: Zimmermann
authors.forename: Daniel
authors.initials: D
authors.lastname: Surbek
authors.forename: Olivier
authors.initials: O
authors.lastname: Irion
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001510:Bed Rest; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D054791:Cervical Length Measurement; D000075202:Contraindications; D016861:Cyclooxygenase Inhibitors / Q000627:therapeutic use; D017277:Drug Approval; D005260:Female; D005280:Fenoterol / Q000627:therapeutic use; D005322:Premature Rupture of Fetal Membranes; D006594:Hexoprenaline / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D031962:Kalanchoe; D007747:Labor Stage, First; D008278:Magnesium Sulfate / Q000627:therapeutic use; D020030:Nitric Oxide Donors / Q000627:therapeutic use; D007752:Obstetric Labor, Premature / Q000188:drug therapy*; D008517:Phytotherapy; D011247:Pregnancy; D047928:Premature Birth / Q000517:prevention & control*; D011374:Progesterone / Q000627:therapeutic use; D011372:Progestins / Q000627:therapeutic use; D018045:Receptors, Oxytocin / Q000037:antagonists & inhibitors; D015145:Tocolysis; D015149:Tocolytic Agents / Q000627:therapeutic use*; D016216:Ultrasonography, Prenatal
chemical_list: D000900:Anti-Bacterial Agents; D002121:Calcium Channel Blockers; D016861:Cyclooxygenase Inhibitors; D020030:Nitric Oxide Donors; D011372:Progestins; D018045:Receptors, Oxytocin; D015149:Tocolytic Agents; D005280:Fenoterol; D011374:Progesterone; D008278:Magnesium Sulfate; D006594:Hexoprenaline