title: Reduced level of physical activity in Japanese patients with chronic obstructive pulmonary disease.
abstract: BACKGROUND
  There is increasing interest in the quantification of physical activity (PA) with an accelerometer for the management of chronic obstructive pulmonary disease (COPD). However, a detailed understanding of the PA in Japanese patients with COPD is lacking. We evaluated the levels of PA in terms of intensity in Japanese patients with COPD and evaluated the factors, which could influence the PA.
  
  
  METHODS
  Forty-three outpatients with COPD and 21 age-matched healthy subjects were monitored with a triaxial accelerometer, and their PA was compared. Furthermore, the effects of pulmonary function, ADO index (age, dyspnea, and airflow obstruction) and modified BODE index (body mass index, airflow obstruction, dyspnea, and exercise capacity) on the PA were evaluated.
  
  
  RESULTS
  The PA in COPD was significantly reduced at all intensities. The reduced levels of PA in COPD were 23.1% at ≥2.0 metabolic equivalents (METs), 33.0% at ≥2.5 METs, 50.9% at ≥3.0 METs, and 66.9% at ≥3.5 METs, compared with that of healthy subjects, and the reduction was significant at GOLD stage III. The values of FVC, FEV1.0, and DLCO/VA were correlated with that of the PA, but the lung volume parameters were not. The ADO and modified BODE indices were also well correlated with the PA.
  
  
  CONCLUSIONS
  The reduced levels of PA in Japanese patients with COPD were objectively demonstrated in terms of intensity that could provide us a new target for the management of COPD.
authors.affiliation: Third Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan. Electronic address: minakaty@wakayama-med.ac.jp.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Minakata
authors.affiliation: Third Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan. Electronic address: alternate_hope_and_fear_0806@yahoo.co.jp.
authors.forename: Akihito
authors.initials: A
authors.lastname: Sugino
authors.affiliation: Third Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan. Electronic address: k97025@yahoo.co.jp.
authors.forename: Masae
authors.initials: M
authors.lastname: Kanda
authors.affiliation: Third Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan. Electronic address: 1kawa@wakayama-med.ac.jp.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Ichikawa
authors.affiliation: Third Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan. Electronic address: akamatsu@wakayama-med.ac.jp.
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Akamatsu
authors.affiliation: Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Miyagi, Japan. Electronic address: koarai@rm.med.tohoku.ac.jp.
authors.forename: Akira
authors.initials: A
authors.lastname: Koarai
authors.affiliation: Third Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan. Electronic address: tsuna@wakayama-med.ac.jp.
authors.forename: Tsunahiko
authors.initials: T
authors.lastname: Hirano
authors.affiliation: Third Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan. Electronic address: masa-n@wakayama-med.ac.jp.
authors.forename: Masanori
authors.initials: M
authors.lastname: Nakanishi
authors.affiliation: Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Miyagi, Japan. Electronic address: sugiura@rm.med.tohoku.ac.jp.
authors.forename: Hisatoshi
authors.initials: H
authors.lastname: Sugiura
authors.affiliation: Third Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan. Electronic address: kazmatsu@wakayama-med.ac.jp.
authors.forename: Kazuto
authors.initials: K
authors.lastname: Matsunaga
authors.affiliation: Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Miyagi, Japan. Electronic address: ichinose@rm.med.tohoku.ac.jp.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Ichinose
mesh_terms: D061725:Accelerometry / Q000295:instrumentation; D000367:Age Factors; D000368:Aged; D044466:Asian People; D015992:Body Mass Index; D004417:Dyspnea; D006801:Humans; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D009043:Motor Activity / Q000502:physiology*; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D012129:Respiratory Function Tests
keywords: ADO index; Accelerometer; BODE index; COPD; Intensity; METs; MMRC; PA; index including age, dyspnea, and airflow obstruction; index including body-mass index, airflow obstruction, dyspnea, and exercise capacity; metabolic equivalents; modified Medical Research Council; physical activity