title: A review of maternally inherited diabetes and deafness.
abstract: Maternally inherited diabetes and deafness (MIDD), a mitochondrial disease first described in 1992, results from the mitochondrial DNA mutation and affects up to 1% of the patients with diabetes. This review discusses the biomedical mechanisms of MIDD patients; summarizes the recent improvement of clinical and genetic diagnosis of MIDD; outlines the advances of the clinical management of these patients and their families.
authors.affiliation: Institute for Integrated Traditional and Western Medicine, the Second Affiliated Hospital of Xingtai Medical College, Xingtai 054000, Hebei Province, China.
authors.forename: Hui-Zhen
authors.initials: HZ
authors.lastname: Li
authors.affiliation: Institute for Integrated Traditional and Western Medicine, the Second Affiliated Hospital of Xingtai Medical College, Xingtai 054000, Hebei Province, China.
authors.forename: Rui-Yu
authors.initials: RY
authors.lastname: Li
authors.affiliation: Department of Health, Hotan Detachment of the Xinjiang Armed Police Corps, Hotan 848011, Xinjiang Uygur Autonomous Region, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Li
mesh_terms: D004272:DNA, Mitochondrial / Q000235:genetics; D003638:Deafness / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006801:Humans; D028361:Mitochondrial Diseases; D025202:Molecular Diagnostic Techniques; D009154:Mutation; D011247:Pregnancy
chemical_list: D004272:DNA, Mitochondrial