title: [A case involving long-term survival following bile duct cancer with para-aortic lymph node metastasis that was treated by multidisciplinary therapy].
abstract: Complete resection of advanced bile duct cancer is difficult due to the anatomical location of the tumor and invasion into other organs. Even if a complete resection is achieved, the survival rates of patients with bile duct cancer after surgery are lower as compared to those associated with other gastrointestinal tumors. Certain cases with para-aortic lymph node metastasis have a poor prognosis. In the present report, we describe a case involving long-term survival following bile duct cancer that was treated by multidisciplinary therapy (particle radiotherapy, surgical resection, chemotherapy). In the present case, we detected lymph node (LN) metastasis only in LN#16, but not in LN#13 or LN#17. We believe that particle radiotherapy, consisting of proton and carbon-ion, can be used to control the lymphatic metastasis around the pancreas head and hepatoduodenal ligament. Our findings suggest that particle radiotherapy can be a standard neoadjuvant therapy for bile duct cancer.
authors.affiliation: Dept. of Surgery, Division of Hepato-Bilialy-Pancreatic Surgery, Kobe University Graduate School of Medicine.
authors.forename: Isamu
authors.initials: I
authors.lastname: Yamada
authors.forename: Kenta
authors.initials: K
authors.lastname: Shinozaki
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Ajiki
authors.forename: Taro
authors.initials: T
authors.lastname: Okazaki
authors.forename: Yuko
authors.initials: Y
authors.lastname: Yoshida
authors.forename: Sae
authors.initials: S
authors.lastname: Murakami
authors.forename: Izuru
authors.initials: I
authors.lastname: Otsubo
authors.forename: Sachiyo
authors.initials: S
authors.lastname: Shirakawa
authors.forename: Masaki
authors.initials: M
authors.lastname: Tanaka
authors.forename: Hideyo
authors.initials: H
authors.lastname: Mukubo
authors.forename: Naohiro
authors.initials: N
authors.lastname: Goto
authors.forename: Sadaki
authors.initials: S
authors.lastname: Asari
authors.forename: Makoto
authors.initials: M
authors.lastname: Shinzeki
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kido
authors.forename: Ippei
authors.initials: I
authors.lastname: Matsumoto
authors.forename: Takumi
authors.initials: T
authors.lastname: Fukumoto
authors.forename: Masao
authors.initials: M
authors.lastname: Murakami
authors.forename: Yonson
authors.initials: Y
authors.lastname: Ku
mesh_terms: D001011:Aorta / Q000473:pathology; D001650:Bile Duct Neoplasms / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D013997:Time Factors; D016896:Treatment Outcome