title: Ipilimumab-induced orbital inflammation resembling Graves disease with subsequent development of systemic hyperthyroidism from CTLA-4 receptor suppression.
authors.forename: Gary E
authors.initials: GE
authors.lastname: Borodic
authors.forename: David
authors.initials: D
authors.lastname: Hinkle
mesh_terms: D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D060908:CTLA-4 Antigen / Q000037:antagonists & inhibitors*; D006111:Graves Disease / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D006980:Hyperthyroidism / Q000139:chemically induced* / Q000175:diagnosis; D000074324:Ipilimumab; D009382:Neoplasms, Unknown Primary / Q000188:drug therapy; D055622:Orbital Myositis / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents; D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; D000074324:Ipilimumab