title: Clear cell adenocarcinoma of the renal pelvis: an extremely rare neoplasm of the upper urinary tract.
abstract: Clear cell adenocarcinoma (CCA) in the urinary tract is a rare neoplasm morphologically identical to the Müllerian counterpart. Clear cell adenocarcinoma is extremely rare in the upper urinary tract. We present a case with CCA of the renal pelvis. Microscopically, the tumor exhibited exophytic growth with predominantly tubulocystic structures, as well as solid and papillary patterns. The neoplastic cells were cuboidal with clear to pale eosinophilic cytoplasm and abundant intracellular and extracellular eosinophilic hyaline globules. By immunohistochemically, the tumor was labeled by cytokeratins and hepatocyte nuclear factor-1β. The patient was still alive without evidence of recurrence in the follow-up period of nineteen months after diagnosis.
authors.affiliation: I-Wei Chang, MD, Department of Pathology, E-DA Hospital No. 1, Yi-Da Road, Jiao-Su Village, Yan-Chao District, Kaohsiung City 824, Taiwan, tel. +886-7-615-0011 ext. 2620, fax +886-7-615-0974, e-mail: ed106242@edah.org.tw.
authors.forename: K-W
authors.initials: KW
authors.lastname: Liu
authors.forename: V C-H
authors.initials: VC
authors.lastname: Lin
authors.forename: I-W
authors.initials: IW
authors.lastname: Chang
mesh_terms: D000005:Abdomen / Q000473:pathology; D018262:Adenocarcinoma, Clear Cell / Q000473:pathology*; D000328:Adult; D014408:Biomarkers, Tumor / Q000378:metabolism*; D005260:Female; D051539:Hepatocyte Nuclear Factor 1-beta / Q000378:metabolism; D006801:Humans; D053552:Keratin-7 / Q000378:metabolism; D007680:Kidney Neoplasms / Q000473:pathology*; D007682:Kidney Pelvis / Q000473:pathology; D011860:Radiography, Abdominal
chemical_list: D014408:Biomarkers, Tumor; D053552:Keratin-7; D051539:Hepatocyte Nuclear Factor 1-beta