title: Perfusion CT of head and neck cancer.
abstract: We aim to review the technique and clinical applications of perfusion CT (PCT) of head and neck cancer. The clinical value of PCT in the head and neck includes detection of head and neck squamous cell carcinoma (HNSCC) as it allows differentiation of HNSCC from normal muscles, demarcation of tumor boundaries and tumor local extension, evaluation of metastatic cervical lymph nodes as well as determination of the viable tumor portions as target for imaging-guided biopsy. PCT has been used for prediction of treatment outcome, differentiation between post-therapeutic changes and tumor recurrence as well as monitoring patient after radiotherapy and/or chemotherapy. PCT has a role in cervical lymphoma as it may help in detection of response to chemotherapy and early diagnosis of relapsing tumors.
authors.affiliation: Diagnostic Radiology Department, Mansoura Faculty of Medicine, Mansoura 13551, Egypt. Electronic address: arazek@mans.edu.eg.
authors.forename: Ahmed Abdel Khalek Abdel
authors.initials: AA
authors.lastname: Razek
authors.affiliation: Diagnostic Radiology Department, Mansoura Faculty of Medicine, Mansoura 13551, Egypt. Electronic address: ahm_m_tawfik@hotmail.com.
authors.forename: Ahmed Mohamed
authors.initials: AM
authors.lastname: Tawfik
authors.affiliation: Diagnostic Radiology Department, Mansoura Faculty of Medicine, Mansoura 13551, Egypt. Electronic address: lamia2elsorogy@hotmail.com.
authors.forename: Lamiaa Galal Ali
authors.initials: LG
authors.lastname: Elsorogy
authors.affiliation: Diagnostic Radiology Department, Mansoura Faculty of Medicine, Mansoura 13551, Egypt. Electronic address: nermin_eid@hotmail.com.
authors.forename: Nermin Yehia
authors.initials: NY
authors.lastname: Soliman
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging*; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging*; D055420:Perfusion Imaging / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods*; D000077195:Squamous Cell Carcinoma of Head and Neck; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: Head and neck; Perfusion CT; Recurrence; Squamous cell carcinoma