title: Cryptogenic organizing pneumonia associated with radiation: A report of two cases.
abstract: Cryptogenic organizing pneumonia (COP) following radiotherapy is occasionally diagnosed as radiation pneumonitis or bacterial pneumonia. The current study presents two cases of COP following radiotherapy: A 48-year-old premenopausal female with breast cancer and an 84-year-old male with non-small cell lung cancer. In the cases of breast cancer and lung cancer, patients were first diagnosed with bacterial pneumonia and radiation pneumonitis, respectively. In the two cases, computed tomography disclosed the migration of ground glass shadows, which were finally resolved without any fibrotic changes. The two cases were finally diagnosed as COP associated with radiotherapy. When an infiltrating shadow is present outside of the irradiated field, COP must be included in the differential diagnosis.
authors.affiliation: Department of Radiology, Tokyo Medical University, Shinjuku, Tokyo 1600023, Japan.
authors.forename: Sachika
authors.initials: S
authors.lastname: Nogi
authors.affiliation: Department of Radiology, Tokyo Medical University, Shinjuku, Tokyo 1600023, Japan.
authors.forename: Hidetsugu
authors.initials: H
authors.lastname: Nakayama
authors.affiliation: Department of Radiology, Tokyo Medical University, Shinjuku, Tokyo 1600023, Japan.
authors.forename: Yu
authors.initials: Y
authors.lastname: Tajima
authors.affiliation: Department of Radiology, Tokyo Medical University, Shinjuku, Tokyo 1600023, Japan.
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Okubo
authors.affiliation: Department of Radiology, Tokyo Medical University, Shinjuku, Tokyo 1600023, Japan.
authors.forename: Ryuji
authors.initials: R
authors.lastname: Mikami
authors.affiliation: Department of Radiology, Tokyo Medical University, Shinjuku, Tokyo 1600023, Japan.
authors.forename: Shinji
authors.initials: S
authors.lastname: Sugahara
authors.affiliation: Department of Radiology, Tokyo Medical University, Shinjuku, Tokyo 1600023, Japan.
authors.forename: Soichi
authors.initials: S
authors.lastname: Akata
authors.affiliation: Department of Radiology, Tokyo Medical University, Shinjuku, Tokyo 1600023, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Tokuuye
keywords: breast cancer; cryptogenic organizing pneumonia; irradiation; non-small cell lung cancer