title: [A cross-sectional study on serum uric acid level and the distribution of metabolic syndrome among Uigur, Han and Kazak prediabetic groups in Xinjiang].
abstract: OBJECTIVE
  To explore the levels of uric acid, blood pressure, serum lipid metabolic disorders and the distribution of obesity and metabolic syndrome (MS) among Uygur, Han and Kazak pre-diabetic groups in Xinjiang.
  
  
  METHODS
  A cross-sectional study was conducted on 2053 Uygur residents, 2219 Kazak residents and 2656 Han residents aged 30-80, all with prediabetic syndromes. The pre-dialectic patients were divided into three groups for analysis on metabolic features and inter-group comparisons.
  
  
  RESULTS
  (1)In total, 1934 pre-diabetic cases (28.3%)were diagnosed, with the highest prevalence (31.6%) seen in Uygurs and the lowest (25.5%) in Kazaks and medium (27.0%) in Hans. Data from the inter-group comparison showed statistically significant differences (P = 0.00). (2)Prevalence of high LDL-C was 80.5% , with hyperuricemia as 30.3% and MS as 58.3% , while the inter-group comparison did not show any statistically significant differences (P > 0.05). (3) Prevalence of pre-diabetic when combined with hypertension or earlier-stage hypertension, reached 88.0%, with the highest (96.8%) among Kazak group, 85.1% in Uygurs and 83.7% in Han population. Data from the inter-group comparison showed statistically significant difference(χ(2) = 59.959, P = 0.00). (4)The overall prevalence of prediabetic, when combined with obesity was 35.4%, with 29.6% in Han, 36.8% in Uygur and 41.0% in Kazak groups. Data from the inter-group comparison showed statistically significant difference(χ(2) = 19.097, P = 0.00).
  
  
  CONCLUSIONS
  According to results from this cross-sectional study regarding the metabolic features of Uygur, Kazak and Han prediabetic groups, differences were seen in the prevalence rates of pre-diabetic among Uygur, Kazak and Han ethnic groups, with the highest seen in Uygurs and the lowest in Kazaks. Hyperlipidemia, hypertension, hyperuricemia,MS and obesity were commonly seen in all the prediabetic groups, with the highest prevalence of hypertension seen in the Kazak group and the highest rate of obesity in Uygur group.
authors.affiliation: Department of Endocrinology, Zhongnan Hospital of Wuhan University, Wuchang 430071, China; Department of Endocrinology, People's Hospital of Xinjiang Uygur Autonomous Region.
authors.forename: Hong-wu
authors.initials: HW
authors.lastname: Zhang
authors.affiliation: Department of Endocrinology, First Affiliate Hospital of Xinjiang Medical University.
authors.forename: Sheng
authors.initials: S
authors.lastname: Jiang
authors.affiliation: Department of Endocrinology, Zhongnan Hospital of Wuhan University, Wuchang 430071, China.
authors.forename: Yan-cheng
authors.initials: YC
authors.lastname: Xu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000453:epidemiology; D008875:Middle Aged; D008913:Minority Groups; D011236:Prediabetic State / Q000097:blood* / Q000453:epidemiology*; D012307:Risk Factors; D014527:Uric Acid / Q000097:blood*
chemical_list: D014527:Uric Acid