title: DisseminatedFusariuminfection in a patient with acute lymphoblastic leukemia: A case report and review of the literature.
abstract: Fusariumis a common soil mold. In severely immunocompromised patients, this fungus may cause disseminated disease and is often confused withAspergillus, as the two pathogens have similar histopathological appearances. DisseminatedFusariuminfection may cause significant morbidity and mortality in immunocompromised patients. The current case report presents a 20-year-old male with acute lymphoblastic leukemia who developed disseminatedFusariuminfection during induction chemotherapy. Early diagnosis and treatment is extremely important since the mortality rate is extremely high in such patients. The clinician must consider that the clinical presentation ofFusariuminfection resembles that ofAspergillus. There is no optimal treatment for patients withFusariuminfection; however, combination antifungal therapy may have benefit without significant toxicity.
authors.affiliation: Division of Hematology and Oncology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan, R.O.C. ; Department of Medicine, Taichung Armed Forces General Hospital, Taichung 41152, Taiwan, R.O.C.
authors.forename: Yi-Sheng
authors.initials: YS
authors.lastname: Liu
authors.affiliation: Division of Infectious Disease, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan, R.O.C.
authors.forename: Ning-Chi
authors.initials: NC
authors.lastname: Wang
authors.affiliation: Division of Hematology and Oncology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan, R.O.C.
authors.forename: Ren-Hua
authors.initials: RH
authors.lastname: Ye
authors.affiliation: Division of Hematology and Oncology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan, R.O.C. ; Division of Hematology and Oncology, Department of Medicine, Taipei Tzu Chi General Hospital, Taipei 23142, Taiwan, R.O.C.
authors.forename: Wei-Yao
authors.initials: WY
authors.lastname: Kao
keywords: Aspergillus; Fusarium; acute leukemia; neutropenia