title: Efficacy, safety and effectiveness of image-guided percutaneous microwave ablation in cystic renal lesions Bosniak III or IV after 24 months follow up.
abstract: OBJECTIVE
  The aim of the study was to assess the efficacy, safety and effectiveness of percutaneous image-guided microwave ablation (MWA) in Bosniak category III or IV cystic renal lesions after 24 months follow-up duration.
  
  
  METHODS
  Between May 2008 and December 2012, computed tomography (CT)- or ultrasound (US)-guided MWA was performed in 6 patients with 7 cystic renal lesions (range 13.8-27 mm, mean 17.02 mm, SD 8.5 mm) Bosniak category III or IV. The number of treatment sessions, treatment results, lesion size changes and complications were evaluated. Technical success (TS), technical effectiveness (TE), local tumor progression rate (LTPR), cancer-specific survival rate (CSSR) and overall survival rate (OSR) were computed.
  
  
  RESULTS
  TS was 100% (7/7) and TE was 100%; LTPR was 0%; CSSR and OSR were 100%. No major complications were observed.
  
  
  CONCLUSIONS
  Our preliminary experience with MWA shows a potential role for US/CT-guided percutaneous MWA in treating Bosniak category III or IV cystic renal lesions, as a safe approach to treat selected patients not suitable for surgery.
authors.affiliation: Interventional Radiology - Department of Radiology, University of Insubria, Varese, Italy.
authors.forename: Gianpaolo
authors.initials: G
authors.lastname: Carrafiello
authors.affiliation: Department of Surgery - University of Insubria, Varese, Italy.
authors.forename: Gianlorenzo
authors.initials: G
authors.lastname: Dionigi
authors.affiliation: Interventional Radiology - Department of Radiology, University of Insubria, Varese, Italy.
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Ierardi
authors.affiliation: Interventional Radiology - Department of Radiology, University of Insubria, Varese, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Petrillo
authors.affiliation: Interventional Radiology - Department of Radiology, University of Insubria, Varese, Italy.
authors.forename: Federico
authors.initials: F
authors.lastname: Fontana
authors.affiliation: Interventional Radiology - Department of Radiology, University of Insubria, Varese, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Floridi
authors.affiliation: Department of Surgery - University of Insubria, Varese, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Boni
authors.affiliation: Department of Surgery - University of Insubria, Varese, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Rovera
authors.affiliation: Department of Surgery - University of Insubria, Varese, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Rausei
authors.affiliation: Department of Surgery - University of Insubria, Varese, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Mangano
authors.affiliation: Department of Surgery - University of Insubria, Varese, Italy.
authors.forename: Sebastiano
authors.initials: S
authors.lastname: Spampatti
authors.affiliation: Division of Urology - Ospedale di Circolo, Fondazione Macchi, Varese, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Marconi
authors.affiliation: Department of Surgery - University of Insubria, Varese, Italy.
authors.forename: Giulio
authors.initials: G
authors.lastname: Carcano
authors.affiliation: Department of Surgery - University of Insubria, Varese, Italy.
authors.forename: Renzo
authors.initials: R
authors.lastname: Dionigi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017115:Catheter Ablation / Q000009:adverse effects* / Q000379:methods*; D005260:Female; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000000981:diagnostic imaging / Q000601:surgery*; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery; D008297:Male; D008872:Microwaves; D008875:Middle Aged; D011859:Radiography; D012189:Retrospective Studies; D025321:Surgery, Computer-Assisted / Q000009:adverse effects* / Q000379:methods*; D014463:Ultrasonography
keywords: Bosniak category III or IV cystic lesion treatment; Heatsink effect; Kidney neoplasm; Microwave ablation therapy