title: Rasburicase for acute kidney injury.
abstract: BACKGROUND
  Acute kidney injury (AKI) continues to have significant mortality and morbidity and the search is on for any novel therapeutic intervention.
  
  
  METHODS
  Two cases of AKI with elevated SUA (serum uric acid).
  
  
  METHODS
  Rasburicase.
  
  
  RESULTS
  In Case 1 (late preterm male with AKI) rasburicase resulted in a significant reduction of SUA along with improvement in renal parameters. In Case 2 (6 yrs old boy with multi organ failure), rasburicase failed to provide any significant benefit despite fall in SUA.
  
  
  CONCLUSIONS
  The effect of rasburicase in AKI needs to be studied.
authors.affiliation: Vision Care Hospital and Institute of Child Health, Kolkata, India. Correspondence to: Dr Rajiv Sinha, 37, G Bondel Road, Kolkata 700 019, India. rajivsinha_in@yahoo.com.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Sinha
authors.forename: Priya
authors.initials: P
authors.lastname: Dugar
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood / Q000188:drug therapy*; D002648:Child; D003404:Creatinine / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D014503:Urate Oxidase / Q000627:therapeutic use*; D014527:Uric Acid / Q000097:blood
chemical_list: C469709:rasburicase; D014527:Uric Acid; D003404:Creatinine; D014503:Urate Oxidase