title: Antibacterial activity of Pd(II) complexes with salicylaldehyde-amino acids Schiff bases ligands.
abstract: Palladium(II) complexes with Schiff bases ligands derived from salicylaldehyde and amino acids (Ala, Gly, Met, Ser, Val) have been synthesized and characterized by Fourier transform (FT)-IR, UV-Vis and (1)H-NMR spectroscopy. The electrospray mass spectrometry (ES-MS) spectrometry confirms the formation of palladium(II) complexes in 1/2 (M/L) molar ratio. All the Pd(II) complexes 1, [Pd(SalAla)2]Cl2; 2, [Pd(SalGly)2]Cl2; 3, [Pd(SalMet)2]Cl2; 4, [Pd(SalSer)2]Cl2; 5, [Pd(SalVal)2]Cl2; have shown antibacterial activity against Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli.
authors.affiliation: Faculty of Veterinary Medicine, Microbiology-Immunology Department Iaşi, University of Agricultural Sciences and Veterinary Medicine Iaşi.
authors.forename: Cristina
authors.initials: C
authors.lastname: Rîmbu
authors.forename: Ramona
authors.initials: R
authors.lastname: Danac
authors.forename: Aurel
authors.initials: A
authors.lastname: Pui
mesh_terms: D000447:Aldehydes / Q000737:chemistry* / Q000494:pharmacology; D000596:Amino Acids / Q000737:chemistry* / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D008024:Ligands; D010165:Palladium / Q000737:chemistry* / Q000494:pharmacology*; D012545:Schiff Bases / Q000737:chemistry* / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000447:Aldehydes; D000596:Amino Acids; D000900:Anti-Bacterial Agents; D008024:Ligands; D012545:Schiff Bases; C013243:salicylaldehyde; D010165:Palladium