title: Off-pump surgery: is it beneficial in patients with left ventricular dysfunction?
abstract: On-pump coronary artery bypass surgery remains the gold standard for complex multivessel disease. Off-pump revascularization has matured as a technique over the last twenty years, but is used in less than 20% of cases worldwide. The poor uptake has been attributed to the significant learning curve in learning the procedure and conflicting evidence reports, together with concerns over mortality related conversion, graft patency and completeness of revascularization. Given these concerns, patient selection continues to be paramount and the subgroups that benefit most are hotly debated. Patients with left ventricular dysfunction constitute a high-risk subgroup which is enlarging in size. There is some evidence to suggest that avoidance of cardiopulmonary bypass in this group may lead to superior results in terms of early mortality, non-cardiac complications and organ dysfunction. Even with the theoretical risk of incomplete revascularization, the technique may be an attractive option in managing high-risk patients.
authors.affiliation: Department of Surgery and Cancer, Imperial College London, London, UK.
authors.forename: Omar A
authors.initials: OA
authors.lastname: Jarral
authors.forename: Thanos
authors.initials: T
authors.lastname: Athanasiou
mesh_terms: D001026:Coronary Artery Bypass / Q000379:methods; D047549:Coronary Artery Bypass, Off-Pump / Q000379:methods*; D003324:Coronary Artery Disease / Q000601:surgery; D006801:Humans; D018579:Patient Selection; D012307:Risk Factors; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology / Q000601:surgery*