title: Genetic similarity between Taenia solium cysticerci collected from the two distant endemic areas in North and North East India.
abstract: Taenia solium taeniasis/cysticercosis is a major public health problem in developing countries. This study reports genotypic analysis of T. solium cysticerci collected from two different endemic areas of North (Chandigarh) and North East India (Dibrugarh) by the sequencing of mitochondrial cytochrome c oxidase subunit 1 (cox1) gene. The variation in cox1 sequences of samples collected from these two different geographical regions located at a distance of 2585 km was minimal. Alignment of the nucleotide sequences with different species of Taenia showed the similarity with Asian genotype of T. solium. Among 50 isolates, 6 variant nucleotide positions (0.37% of total length) were detected. These results suggest that population in these geographical areas are homogenous.
authors.affiliation: Department of Parasitology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: mnk.sharma83@gmail.com.
authors.forename: Monika
authors.initials: M
authors.lastname: Sharma
authors.affiliation: Regional Medical Research Center (ICMR), Dibrugarh 786 001, Assam, India. Electronic address: krekha75@yahoo.co.in.
authors.forename: Kangjam Rekha
authors.initials: KR
authors.lastname: Devi
authors.affiliation: Department of Parasitology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: sehgalpgi@gmail.com.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Sehgal
authors.affiliation: Regional Medical Research Center (ICMR), Dibrugarh 786 001, Assam, India. Electronic address: kanwar_narain@hotmail.com.
authors.forename: Kanwar
authors.initials: K
authors.lastname: Narain
authors.affiliation: Regional Medical Research Center (ICMR), Dibrugarh 786 001, Assam, India. Electronic address: jmahanta@gmail.com.
authors.forename: Jagadish
authors.initials: J
authors.lastname: Mahanta
authors.affiliation: Department of Parasitology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: drmallanancy@gmail.com.
authors.forename: Nancy
authors.initials: N
authors.lastname: Malla
mesh_terms: D000818:Animals; D003551:Cysticercosis / Q000469:parasitology / Q000662:veterinary*; D003552:Cysticercus / Q000235:genetics*; D003906:Developing Countries; D019143:Evolution, Molecular; D017238:Genes, Helminth; D014644:Genetic Variation; D005838:Genotype; D007194:India; D010802:Phylogeny; D020539:Sequence Analysis, Protein; D013552:Swine; D013553:Swine Diseases / Q000469:parasitology*; D041201:Taenia solium / Q000145:classification* / Q000235:genetics*
keywords: Cysticerci; India; Mitochondrial cox1 gene; Sequencing; Taenia solium