title: [A case of advanced gastric cancer with carcinomatous lymphangitis of the lung treated with docetaxel and S-1 combination chemotherapy].
abstract: A 67-year-old woman with complaints of cough and dyspnea was admitted; her chest radiographs and computed tomography (CT) scans revealed pulmonary carcinomatous lymphangitis. Endoscopic examination revealed advanced gastric cancer and the patient was treated with a combination of 40 mg/m2 docetaxel, administered on day 1, and S-1 100 mg/body/day, administered for 14 days followed by a 7-day interval, as 1 course despite her performance status( PS) being grade 3. After 2 courses of chemotherapy, CT showed that the carcinomatous lymphangitis had improved, and the patient was discharged with PS of grade 0. We report that combination chemotherapy with docetaxel and S-1 might be effective for the treatment of advanced gastric cancer with carcinomatous lymphangitis of the lung in patients with a poor systemic condition.
authors.affiliation: Dept. of Gastroenterology, Tokyo Metropolitan Toshima Hospital.
authors.forename: Eiko
authors.initials: E
authors.lastname: Okamoto
authors.forename: Kentaro
authors.initials: K
authors.lastname: Takagi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Tamura
authors.forename: Mayumi
authors.initials: M
authors.lastname: Kondo
authors.forename: Satoko
authors.initials: S
authors.lastname: Hanada
authors.forename: Haruyasu
authors.initials: H
authors.lastname: Sakuranaka
authors.forename: Junichi
authors.initials: J
authors.lastname: Ochi
authors.forename: Michiko
authors.initials: M
authors.lastname: Tanaka
authors.forename: Shikofumi
authors.initials: S
authors.lastname: Tei
authors.forename: Masahiko
authors.initials: M
authors.lastname: Ichioka
authors.forename: Takao
authors.initials: T
authors.lastname: Shibayama
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000077143:Docetaxel; D004338:Drug Combinations; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008205:Lymphangitis / Q000209:etiology*; D010094:Oxonic Acid / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology; D043823:Taxoids / Q000008:administration & dosage; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D043823:Taxoids; C079198:S 1 (combination); D005641:Tegafur; D000077143:Docetaxel; D010094:Oxonic Acid