title: The exocyst subunit Exo70B1 is involved in the immune response of Arabidopsis thaliana to different pathogens and cell death.
abstract: Components of the vesicle trafficking machinery are central to the immune response in plants. The role of vesicle trafficking during pre-invasive penetration resistance has been well documented. However, emerging evidence also implicates vesicle trafficking in early immune signaling. Here we report that Exo70B1, a subunit of the exocyst complex which mediates early tethering during exocytosis is involved in resistance. We show that exo70B1 mutants display pathogen-specific immuno-compromised phenotypes. We also show that exo70B1 mutants display lesion-mimic cell death, which in combination with the reduced responsiveness to pathogen-associated molecular patterns (PAMPs) results in complex immunity-related phenotypes.
authors.affiliation: Leibniz Institute of Plant Biochemistry; Halle, (Saale) Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Stegmann
authors.affiliation: Department of Plant Pathology, Physiology, & Weed Science; Virginia Tech; Blacksburg, VA USA.
authors.forename: Ryan G
authors.initials: RG
authors.lastname: Anderson
authors.affiliation: Leibniz Institute of Plant Biochemistry; Halle, (Saale) Germany.
authors.forename: Lore
authors.initials: L
authors.lastname: Westphal
authors.affiliation: Leibniz Institute of Plant Biochemistry; Halle, (Saale) Germany.
authors.forename: Sabine
authors.initials: S
authors.lastname: Rosahl
authors.affiliation: Department of Plant Pathology, Physiology, & Weed Science; Virginia Tech; Blacksburg, VA USA.
authors.forename: John M
authors.initials: JM
authors.lastname: McDowell
authors.affiliation: Leibniz Institute of Plant Biochemistry; Halle, (Saale) Germany.
authors.forename: Marco
authors.initials: M
authors.lastname: Trujillo
mesh_terms: D017360:Arabidopsis / Q000166:cytology* / Q000276:immunology* / Q000382:microbiology; D029681:Arabidopsis Proteins / Q000378:metabolism*; D016923:Cell Death; D009154:Mutation / Q000235:genetics; D010641:Phenotype; D057865:Plant Immunity; D021122:Protein Subunits / Q000378:metabolism*; D033921:Vesicular Transport Proteins / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; C000589008:EXO70B1 protein, Arabidopsis; D021122:Protein Subunits; D033921:Vesicular Transport Proteins
keywords: basal resistance; biotroph; cell death; hemibiotroph; lesion mimic; nonhost resistance; vesicle trafficking