title: Population-based surveillance for bacterial meningitis in China, September 2006-December 2009.
abstract: During September 2006-December 2009, we conducted active population and sentinel laboratory-based surveillance for bacterial meningitis pathogens, including Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae type b, in 4 China prefectures. We identified 7,876 acute meningitis and encephalitis syndrome cases, including 6,388 among prefecture residents. A total of 833 resident cases from sentinel hospitals met the World Health Organization case definition for probable bacterial meningitis; 339 of these cases were among children <5 years of age. Laboratory testing confirmed bacterial meningitis in 74 of 3,391 tested cases. The estimated annual incidence (per 100,000 population) of probable bacterial meningitis ranged from 1.84 to 2.93 for the entire population and from 6.95 to 22.30 for children <5 years old. Active surveillance with laboratory confirmation has provided a population-based estimate of the number of probable bacterial meningitis cases in China, but more complete laboratory testing is needed to better define the epidemiology of the disease in this country.
authors.forename: Yixing
authors.initials: Y
authors.lastname: Li
authors.forename: Zundong
authors.initials: Z
authors.lastname: Yin
authors.forename: Zhujun
authors.initials: Z
authors.lastname: Shao
authors.forename: Manshi
authors.initials: M
authors.lastname: Li
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Liang
authors.forename: Hardeep S
authors.initials: HS
authors.lastname: Sandhu
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Hadler
authors.forename: Junhong
authors.initials: J
authors.lastname: Li
authors.forename: Yinqi
authors.initials: Y
authors.lastname: Sun
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Wenjing
authors.initials: W
authors.lastname: Zou
authors.forename: Mei
authors.initials: M
authors.lastname: Lin
authors.forename: Shuyan
authors.initials: S
authors.lastname: Zuo
authors.forename: Leonard W
authors.initials: LW
authors.lastname: Mayer
authors.forename: Ryan T
authors.initials: RT
authors.lastname: Novak
authors.forename: Bingqing
authors.initials: B
authors.lastname: Zhu
authors.forename: Li
authors.initials: L
authors.lastname: Xu
authors.forename: Huiming
authors.initials: H
authors.lastname: Luo
mesh_terms: D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D062306:Geography, Medical; D006801:Humans; D015994:Incidence; D007223:Infant; D016920:Meningitis, Bacterial / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D011159:Population Surveillance; D012621:Seasons; D018571:Sentinel Surveillance
keywords: China; Haemophilus influenzae type b; Neisseria meningitidis; Streptococcus pneumoniae; bacteria; bacterial meningitis; meningitis; pneumococcal; population-based surveillance