title: A new approach to iliac bone histomorphometry: implications for biomechanics and cell biology.
abstract: I devised a method for obtaining information on cancellous bone structure from iliac bone histomorphometry that led to the demonstration that architecture is an important component of bone strength and bone fragility. Furthermore, this method contributed to the recognition of the importance of changes in osteoclast and osteocyte apoptosis in response to estrogen deficiency and replacement.
authors.forename: A Michael
authors.initials: AM
authors.lastname: Parfitt
mesh_terms: D001696:Biomechanical Phenomena; D015519:Bone Density; D003585:Cell Biology / Q000266:history; D004967:Estrogens / Q000502:physiology; D049673:History, 20th Century; D006801:Humans; D007085:Ilium / Q000378:metabolism / Q000473:pathology*; D008954:Models, Biological; D010010:Osteoclasts / Q000473:pathology; D010024:Osteoporosis / Q000378:metabolism / Q000473:pathology*
chemical_list: D004967:Estrogens