title: [A case of successful radical resection of rectal cancer with neo-adjuvant chemoradiotherapy].
abstract: In cases of advanced rectal cancer, preoperative chemoradiotherapy( CRT) serves to improve the local control rate, survival rate, radical resection rate, and/or probability of sphincter muscle preservation. According to the Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer, preoperative CRT is the standard treatment for rectal cancer in Europe and the United States. However, there is insufficient evidence in support of its efficacy and safety in Japan, and therefore, CRT needs to be evaluated in properly designed clinical trials. Recently, several studies have reported on the efficacy of preoperative CRT in Japan. Herein, we report a case of rectal cancer in which radical resection was successfully performed with neo-adjuvant CRT.
authors.affiliation: Dept. of Surgery, Tokyo Metropolitan Health and Medical Treatment Corporation Toshima Hospital.
authors.forename: Katsunori
authors.initials: K
authors.lastname: Ami
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Kawai
authors.forename: Ryota
authors.initials: R
authors.lastname: Seki
authors.forename: Kentaro
authors.initials: K
authors.lastname: Gokita
authors.forename: Shoko
authors.initials: S
authors.lastname: Takeuchi
authors.forename: Keiichi
authors.initials: K
authors.lastname: Fujiya
authors.forename: Jun
authors.initials: J
authors.lastname: Takasaki
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Amagasa
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Kamikozuru
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ganno
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Imai
authors.forename: Akira
authors.initials: A
authors.lastname: Fukuda
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nagahama
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ando
authors.forename: Youichi
authors.initials: Y
authors.lastname: Okada
authors.forename: Shikofumi
authors.initials: S
authors.lastname: Tei
authors.forename: Kuniyoshi
authors.initials: K
authors.lastname: Arai
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D059248:Chemoradiotherapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D012004:Rectal Neoplasms / Q000628:therapy*; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil