title: [A case of multiple skin metastases from cancer of the descending colon responding to FOLFIRI/cetuximab therapy].
abstract: A 64-year-old woman presented to our hospital with subcutaneous tumors in the right thoracic region. After undergoing a thorough medical evaluation, she was diagnosed with multiple skin metastases arising from cancer of the descending colon. Surgical resection of the primary lesion was performed and FOLFIRI (5-fluorouracil, levofolinate calcium, irinotecan) and cetuximab chemotherapy for the metastases was initiated. The patient subsequently entered remission and did not experience any major side effects. This case report details an effective therapy for colon cancer with multiple skin metastases and presents a discussion of the expression profiles of epidermal growth factor receptor in both the primary and metastatic lesions.
authors.affiliation: Department of Gastroenterology, Aijinkai Takatsuki General Hospital.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Kadota
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Osuga
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Ogawa
authors.forename: Motoya
authors.initials: M
authors.lastname: Kitami
authors.forename: Megumi
authors.initials: M
authors.lastname: Ishimura
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Shigaki
authors.forename: Eishin
authors.initials: E
authors.lastname: Nakajima
authors.forename: Shuji
authors.initials: S
authors.lastname: Nakata
authors.forename: Chikara
authors.initials: C
authors.lastname: Kadota
authors.forename: Seiichi
authors.initials: S
authors.lastname: Hirano
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Ikura
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Iwai
authors.forename: Takuro
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Nozomu
authors.initials: N
authors.lastname: Ueno
authors.forename: Takao
authors.initials: T
authors.lastname: Tamura
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology*; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D000068818:Cetuximab; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008875:Middle Aged; D012878:Skin Neoplasms / Q000556:secondary*
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D000068818:Cetuximab; D002955:Leucovorin; D005472:Fluorouracil; D002166:Camptothecin