title: The characteristics of bisphosphonate patients developing bisphosphonate-related osteonecrosis of the jaw attending an OMFS department.
abstract: This case series considers the incidence of patients taking bisphosphonate medication that suffer with bisphosphonate-related osteonecrosis of the jaw (BRONJ) following an exodontia procedure. Forty five such patients who attended the Wigan Royal Albert Edward Infirmary (RAEI) Oral and Maxillofacial Surgery (OMFS) department for an exodontia procedure were examined. A patient's age, gender, exodontia technique, bisphosphonate route (Oral/IV), smoking status and reason for taking the bisphosphonates, eg osteoporosis/cancer/ arthritis was considered. All of the patients that experienced BRONJ were smokers.
  
  
  CONCLUSIONS
  Bisphosphonates are now widely accepted for the management of medical conditions, including arthritis, osteoporosis and various forms of cancer. Such patients are regularly referred to OMFS departments for dental extractions.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Wigan Royal Albert Edward Infirmary, Lancashire, UK.
authors.forename: Paul S
authors.initials: PS
authors.lastname: Serrant
authors.affiliation: Department of Oral and Maxillofacial Surgery, Wigan Royal Albert Edward Infirmary, Lancashire, UK.
authors.forename: Stuart
authors.initials: S
authors.lastname: Clark
mesh_terms: D061605:Administration, Intravenous; D000284:Administration, Oral; D000368:Aged; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis; D001168:Arthritis / Q000188:drug therapy; D059266:Bisphosphonate-Associated Osteonecrosis of the Jaw / Q000209:etiology*; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy; D010024:Osteoporosis / Q000188:drug therapy; D010174:Pamphlets; D010353:Patient Education as Topic; D012189:Retrospective Studies; D012307:Risk Factors; D012907:Smoking; D014081:Tooth Extraction / Q000379:methods*
chemical_list: D050071:Bone Density Conservation Agents; D019980:Amoxicillin-Potassium Clavulanate Combination