title: Crohn disease: pathophysiology, diagnosis, and treatment.
abstract: Crohn disease (often seen in the literature as "Crohn's disease"), an autoimmune disease with debilitating gastrointestinal and extragastrointestinal manifestations, is on the rise in the United States and Europe. This article discusses the disease process, clinical presentation, diagnostic tools, and treatment options for Crohn disease. Statistics regarding disease prevalence and epidemiology also are reported.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Mazal
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003424:Crohn Disease / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D003952:Diagnostic Imaging / Q000379:methods*; D013505:Digestive System Surgical Procedures / Q000379:methods*; D006801:Humans; D008487:Medical History Taking / Q000379:methods*; D010808:Physical Examination / Q000379:methods*
chemical_list: D000893:Anti-Inflammatory Agents