title: Febuxostat contributes to improvement of endothelial dysfunction in an experimental model of streptozocin-induced diabetic rats.
authors.affiliation: Department of Cardiology, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea.
authors.forename: Seung Joon
authors.initials: SJ
authors.lastname: Hwang
authors.affiliation: Department of Cardiology, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea.
authors.forename: Kyung Hye
authors.initials: KH
authors.lastname: Lee
authors.affiliation: Department of Cardiology, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea.
authors.forename: Hyun Hee
authors.initials: HH
authors.lastname: Jang
authors.affiliation: Department of Cardiology, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea.
authors.forename: So Ra
authors.initials: SR
authors.lastname: Lee
authors.affiliation: Department of Cardiology, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea.
authors.forename: Jong Shin
authors.initials: JS
authors.lastname: Woo
authors.affiliation: Department of Nephrology, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea.
authors.forename: Hong Ju
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: Department of Nephrology, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea.
authors.forename: Kyung Hwan
authors.initials: KH
authors.lastname: Jung
authors.affiliation: Department of Cardiology, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea. Electronic address: mylovwkw@hanmail.net.
authors.forename: Weon
authors.initials: W
authors.lastname: Kim
mesh_terms: D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology*; D004730:Endothelium, Vascular / Q000187:drug effects* / Q000378:metabolism / Q000503:physiopathology*; D000069465:Febuxostat; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D017382:Reactive Oxygen Species / Q000378:metabolism; D013844:Thiazoles / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D017382:Reactive Oxygen Species; D013844:Thiazoles; D000069465:Febuxostat
keywords: Endothelial dysfunction; Nitric oxide; Xanthine oxidase