title: Intraretinal and intra-optic nerve head silicone oil vacuoles using adaptive optics.
abstract: The authors report the in vivo visualization through multimodal imaging of silicone oil in the vitreous cavity, optic nerve, and retina of a patient 11 years after surgical removal of the main tamponade. Contact B-scan ultrasonography revealed countless small echogenic particles in the vitreous cavity and a hyperreflective structure within the optic nerve head. Swept-source optical coherence tomography showed multiple round hyporeflective spaces within the substance of the prelaminar optic nerve head. Adaptive optics imaging revealed numerous particles in the optic nerve head and within the retina in the same plane as the photoreceptors, with similar size and shape to the silicone oil droplets in the vitreous cavity. The authors hypothesize that in this case, the silicone oil droplets in the retina and optic nerve head may be associated with the patient's otherwise unexplained progressive visual loss.
authors.forename: Sarah
authors.initials: S
authors.lastname: Mrejen
authors.forename: Taku
authors.initials: T
authors.lastname: Sato
authors.forename: Yale
authors.initials: Y
authors.lastname: Fisher
authors.forename: Richard F
authors.initials: RF
authors.lastname: Spaide
mesh_terms: D000328:Adult; D004322:Drainage; D058450:Endotamponade; D005128:Eye Diseases / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D009901:Optic Nerve Diseases / Q000175:diagnosis* / Q000209:etiology; D012163:Retinal Detachment / Q000601:surgery; D012164:Retinal Diseases / Q000175:diagnosis* / Q000209:etiology; D012827:Silicone Oils / Q000009:adverse effects*; D041623:Tomography, Optical Coherence; D014463:Ultrasonography; D014617:Vacuoles / Q000473:pathology*; D014786:Vision Disorders / Q000209:etiology*; D014792:Visual Acuity; D014821:Vitrectomy; D014822:Vitreous Body / Q000473:pathology*
chemical_list: D012827:Silicone Oils