title: Tremor in neuropathies of different origin.
abstract: OBJECTIVE
  Tremor accompanies some poly-neuropathies, but its prevalence and its clinical and electrophysiological manifestations are not well known. The aim of the study was to assess the occurrence and characteristics of hand tremor in patients with polyneuropathy of different origins, as well as relations between the occurrence of tremors and clinical and neurographic findings of polyneuropathy.
  
  
  METHODS
  Eighty-nine patients diagnosed with polyneuropathy of known aetiology, and 50 age- and sex-matched healthy volunteers were included in the study. All subjects were interviewed regarding the occurrence of tremor. Tremor was assessed clinically and objectively using a triaxial accelerometer and electromyographic (EMG) recordings. A load test with a weight of 500 γ was performed in order to differentiate between enhanced physiological tremor (EPT) and essential tremor-like (ET-L) tremor.
  
  
  RESULTS
  Tremor was found in 59.5% of patients in clinical assessment and in 74% of patients in objective evaluation, significantly more often than in controls (12%). Tremor was detected in all types of polyneuropathy apart from paraproteinaemic IgM polyneuropathy. Tremor was postural (70%), but resting (51%) or kinetic (32%) tremor was also present. In the majority of cases, the severity of the tremor was mild. Essential tremor-like tremor prevailed in the study group. The occurrence of hand tremor was not related to the axonal or demyelinating type of polyneuropathy, nor to the conduction velocity or other electrophysiological findings of the investigated upper limb nerves.
  
  
  CONCLUSIONS
  Tremor accompanies 60-70% of patients with polyneuropathy; it is mostly postural, ET-L type with mild severity, and unrelated to other typical clinical and electrophysiological findings of neuropathy.
authors.affiliation: Anna Wasielewska, MD, Department of Neurology, Jagiellonian University Medical College, 3 Botaniczna St., Krakow 31-503, Poland, e-mail: anna.wasielewska@tlen.
authors.forename: Anna
authors.initials: A
authors.lastname: Wasielewska
authors.forename: Monika
authors.initials: M
authors.lastname: Rudzińska
authors.forename: Tomasz
authors.initials: T
authors.lastname: Tomaszewski
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Banaszkiewicz
authors.forename: Magdalena
authors.initials: M
authors.lastname: Wójcik-Pędziwiatr
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Dec-Ćwiek
authors.forename: Anna
authors.initials: A
authors.lastname: Zajączkowska
authors.forename: Andrezj
authors.initials: A
authors.lastname: Izworski
authors.forename: Andrezj
authors.initials: A
authors.lastname: Szczudlik
mesh_terms: D061725:Accelerometry / Q000379:methods; D004576:Electromyography / Q000379:methods; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008875:Middle Aged; D011115:Polyneuropathies / Q000150:complications*; D012016:Reference Values; D012720:Severity of Illness Index; D014202:Tremor / Q000175:diagnosis* / Q000209:etiology*