title: [A case of unresectable gastric cancer in a patient who maintained a good quality of life with multidisciplinary treatment].
abstract: Herein, we report the case of 57-year-old woman who visited our hospital for abdominal distention, difficulty in walking, and edema of the legs in January 2012. She underwent gastroendoscopy, resulting in a diagnosis of advanced gastric cancer of the pyloric antrum. A diagnosis of unresectable advanced gastric cancer was made because computed tomography (CT) showed the presence of ascites (suspected to indicate peritoneal dissemination), para-aortic lymph node metastases, and brain metastases. Stenting was performed for pyloric stenosis and cell-free and concentrated ascites reinfusion therapy (CART) was administered to facilitate oral intake. We administered two courses of chemotherapy with weekly paclitaxel. However, CT showed the presence of ascites and growth of the main tumor in the first month after the initiation of chemotherapy. We performed CART, and treatment was changed to S-1/paclitaxe(l 5 courses). Ascites decreased markedly and activities of daily living improved. However, 11 months after the initiation of therapy, the patient died.
authors.affiliation: Dept. of Surgery, Suita Municipal Hospital.
authors.forename: Ryo
authors.initials: R
authors.lastname: Kato
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Okada
authors.forename: Chikara
authors.initials: C
authors.lastname: Ebisui
authors.forename: Yuma
authors.initials: Y
authors.lastname: Wada
authors.forename: Shunichiro
authors.initials: S
authors.lastname: Makino
authors.forename: Tomohira
authors.initials: T
authors.lastname: Takeoka
authors.forename: Tetsu
authors.initials: T
authors.lastname: Yanagisawa
authors.forename: Shu
authors.initials: S
authors.lastname: Okamura
authors.forename: Nariaki
authors.initials: N
authors.lastname: Fukuchi
authors.forename: Kouhei
authors.initials: K
authors.lastname: Murata
authors.forename: Hideoki
authors.initials: H
authors.lastname: Yokouchi
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Kinuta
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001201:Ascites / Q000209:etiology / Q000628:therapy; D001932:Brain Neoplasms / Q000532:radiotherapy / Q000556:secondary; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage; D010534:Peritoneal Neoplasms / Q000188:drug therapy / Q000556:secondary; D011707:Pyloric Stenosis / Q000209:etiology / Q000628:therapy; D011788:Quality of Life; D013274:Stomach Neoplasms / Q000473:pathology / Q000628:therapy*
chemical_list: D017239:Paclitaxel