title: Uncovering the complexity of Tourette syndrome, little by little.
abstract: The aetiology of Tourette syndrome is highly complex and still poorly understood. In this issue, using data from a large, prospective, population-based cohort of children, Mathews et al examine associations of pre- and perinatal exposures with Tourette syndrome and other chronic tic disorders. Their work illustrates the importance of environmental factors in the aetiology of neuropsychiatric conditions and the value of replication in science.
authors.affiliation: Daniel A. Gorman, MD, FRCPC, Department of Psychiatry, University of Toronto and The Hospital for Sick Children, Toronto; Elia Abi-Jaoude, MSc, MD, FRCPC, Department of Psychiatry, University of Toronto and University Health Network (Toronto Western Hospital), Toronto, Canada.
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Gorman
authors.forename: Elia
authors.initials: E
authors.lastname: Abi-Jaoude
mesh_terms: D000428:Alcohol Drinking / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008385:Marijuana Smoking / Q000453:epidemiology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011297:Prenatal Exposure Delayed Effects / Q000453:epidemiology*; D013981:Tic Disorders / Q000453:epidemiology*