title: [Cerebral microbleeds detected on T2-weighted gradient echo magnetic resonance and its clinical significance].
abstract: OBJECTIVE
  To explore the diagnostic value of T2-weighted gradient-echo magnetic resonance imaging (MRI) in cerebral microbleeds (CMBs) and its clinical significance.
  
  
  METHODS
  The distribution of CMBs and follow-up observations were performed by routine T1WI, T2WI and T2-weighted gradient echo sequence in 634 patients clinically suspected for stroke.
  
  
  RESULTS
  In 149 patients, a total of 1140 CMBs occurred predominantly in cortex-subcortical area (n = 471, 41.31%), basal ganglia (n = 289, 25.35%), thalamus (n = 199, 17.45%), brain stem (n = 90, 7.89%) and cerebellum (n = 91, 7.98%). Among them, 137 patients had various degrees of ischemic brain changes, displayed iso-intensity or hypo-intensity on T1WI, hyper-intensity on T2WI and FLAIR in basal ganglia, white matter around sided ventricle and brain stem. There were 23 patients with cerebral infarction and 5 with CMBs after hemorrhagic brain stroke. And 12 of them had new hemorrhagic stroke in 2-6 months.
  
  
  CONCLUSIONS
  T2-weighted gradient echo MRI has obvious advantages in the detection of CMBs. The presence of CMBs suggests a risk of cerebral hemorrhage.
authors.affiliation: Department of Cardiology, Central Municipal Hospital, Lishui 323000, China. Email: lswtm@sina.com.
authors.forename: Tie-min
authors.initials: TM
authors.lastname: Wei
authors.affiliation: Department of Cardiology, Central Municipal Hospital, Lishui 323000, China.
authors.forename: Li-min
authors.initials: LM
authors.lastname: Zhou
authors.affiliation: Department of Cardiology, Central Municipal Hospital, Lishui 323000, China.
authors.forename: Jian-song
authors.initials: JS
authors.lastname: Ji
authors.affiliation: Department of Cardiology, Central Municipal Hospital, Lishui 323000, China.
authors.forename: Li
authors.initials: L
authors.lastname: Lin
authors.affiliation: Department of Cardiology, Central Municipal Hospital, Lishui 323000, China.
authors.forename: Wen-wei
authors.initials: WW
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002543:Cerebral Hemorrhage / Q000175:diagnosis*; D017352:Echo-Planar Imaging; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged