title: [A case of advanced gastric cancer successfully treated with multimodal therapy].
abstract: In November 2010, a 76-year-old man was diagnosed as having advanced gastric cancer with paraaortic lymph node (PALN) metastasis. Systemic chemotherapy was initiated using S-1/docetaxel( DTX) regimen. Regression of the PALN swelling was confirmed after 2 courses. Total gastrectomy with D2 lymph node dissection was performed as a reduction surgery, although intraoperative histopathological examination revealed PALN metastasis. Two months postoperatively, S-1 chemotherapy was initiated for the treatment of residual PALN metastasis. About 8 months postoperatively, abdominal computed tomography( CT) examination indicated complete regression of the PALN enlargement. This patient has been doing well for 30 months since the reduction surgery, with no sign of recurrence. In summary, we successfully treated a case of PALN metastasis with multimodal therapy including systemic chemotherapy and reduction surgery.
authors.affiliation: Dept. of Surgery, Suita Municipal Hospital.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Okada
authors.forename: Chikara
authors.initials: C
authors.lastname: Ebisui
authors.forename: Tetsu
authors.initials: T
authors.lastname: Yanagisawa
authors.forename: Shu
authors.initials: S
authors.lastname: Okamura
authors.forename: Nariaki
authors.initials: N
authors.lastname: Fukuchi
authors.forename: Kohei
authors.initials: K
authors.lastname: Murata
authors.forename: Hideoki
authors.initials: H
authors.lastname: Yokouchi
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Kinuta
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005743:Gastrectomy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery