title: Carotid artery Doppler ultrasonography in patients with chronic kidney disease.
abstract: BACKGROUND
  We investigated the changes in the values of carotid intima-media thickness (IMT) and Doppler index measurements in the autosomal dominant polycystic kidney disease (ADPKD), peritoneal dialysis (PD), and hemodialysis (HD) patients.
  
  
  METHODS
  Twenty outpatients on HD (mean age 46.1 ± 16.4), 27 outpatients on PD (mean age 45 ± 12.4), and 26 normotensive outpatients with ADPKD (mean age 52.4 ± 16.7) as the case groups and 21 healthy subjects (mean age 48.4 ± 7.2), as the control group, were included. The participants underwent ultrasonography of the common, right, and left carotid arteries for the IMT and Doppler flow measurements.
  
  
  RESULTS
  Overall, compared to the normal group, in the study groups, the IMT and peak systolic velocity (PSV), end-diastolic velocity (EDV), resistive index (RI), and pulsatility index (PI) were significantly higher in common carotid arteries; however, their differences were not meaningful in internal carotid arteries (p<0.05).
  
  
  CONCLUSIONS
  Overall, ADPKD, PD, and HD increase the IMT, PSV, EDV, RI, and PI values of CCA; however, their effect considerable less on the study parameters of ICA. There is no considerable difference among the effects of ADPKD, HD, and PD on the study parameters. Of CKD patients during the first diagnostic and follow-up workups, the measurements of carotid IMT and Doppler indices may provide valuable data for improving success of the clinical management.
authors.affiliation: Department of Radiology, Cumhuriyet University, Faculty of Medicine, Sivas, Turkey.
authors.forename: Ismail
authors.initials: I
authors.lastname: Salk
authors.affiliation: Department of Nephrology, Cumhuriyet University, Faculty of Medicine, Sivas, Turkey.
authors.forename: Gursel
authors.initials: G
authors.lastname: Yildiz
authors.affiliation: Department of Radiology, Cumhuriyet University, Faculty of Medicine, Sivas, Turkey.
authors.forename: Hulusi
authors.initials: H
authors.lastname: Egilmez
authors.affiliation: Department of Radiology, Cumhuriyet University, Faculty of Medicine, Sivas, Turkey.
authors.forename: Mehmet Haydar
authors.initials: MH
authors.lastname: Atalar
authors.affiliation: Department of Nephrology, Cumhuriyet University, Faculty of Medicine, Sivas, Turkey.
authors.forename: Ferhan
authors.initials: F
authors.lastname: Candan
authors.affiliation: Department of Obstetrics and Gynecology, Cumhuriyet University, Faculty of Medicine, Sivas, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Cetin
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002339:Carotid Arteries / Q000000981:diagnostic imaging*; D016022:Case-Control Studies; D006801:Humans; D008875:Middle Aged; D016891:Polycystic Kidney, Autosomal Dominant / Q000473:pathology*; D006435:Renal Dialysis; D017539:Tunica Intima / Q000000981:diagnostic imaging*; D018608:Ultrasonography, Doppler / Q000379:methods*