title: Comorbidity profile of chronic rhinosinusitis: a population-based study.
abstract: OBJECTIVE
  This study aimed to explore the prevalence of a broad spectrum of comorbid medical conditions among patients with chronic rhinosinusitis (CRS), using a population-based dataset.
  
  
  METHODS
  A cross-sectional study.
  
  
  METHODS
  In total, 5,734 CRS subjects and 17,202 comparison subjects were included in this study. Separate conditional logistic regression analyses were performed to calculate the odds ratio (OR) for each of 39 medical comorbidities between subjects with and without CRS.
  
  
  RESULTS
  For 27 of the 39 study comorbidities, results showed that subjects with CRS had a statistically significantly higher OR than subjects without CRS after adjusting for sociodemographic characteristics. Ranks of the top five comorbid relationships from the strongest ORs to the lowest were as follows: asthma (OR=3.09), chronic pulmonary disease (OR=3.04), weight loss (OR=2.58), obesity (OR=2.50), and migraines (OR=2.30).
  
  
  CONCLUSIONS
  Our results indicate that subjects with CRS have an increased prevalence of various comorbidities.
  
  
  METHODS
  3b.
authors.affiliation: Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, Taipei Medical University-Shuang Ho Hospital, New Taipei City; Sleep Research Center; Taipei Medical University Hospital, Taipei, Taiwan.
authors.forename: Shiu-Dong
authors.initials: SD
authors.lastname: Chung
authors.forename: Po-Yueh
authors.initials: PY
authors.lastname: Chen
authors.forename: Herng-Ching
authors.initials: HC
authors.lastname: Lin
authors.forename: Shih-Han
authors.initials: SH
authors.lastname: Hung
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000453:epidemiology*; D002908:Chronic Disease; D015897:Comorbidity / Q000639:trends; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology*; D016017:Odds Ratio; D011159:Population Surveillance; D015995:Prevalence; D012189:Retrospective Studies; D012220:Rhinitis / Q000453:epidemiology*; D012852:Sinusitis / Q000453:epidemiology*; D055815:Young Adult
keywords: Chronic rhinosinusitis; comorbidity