title: Pneumonia and empyema caused by Streptococcus intermedius that shows the diagnostic importance of evaluating the microbiota in the lower respiratory tract.
abstract: The bacterial species in the Streptococcus anginosus group (S. constellatus, S. anginosus, S. intermedius) are important causative pathogens of bacterial pneumonia, pulmonary abscesses and empyema. However, the bacteria in this group are primarily oral resident bacteria and unable to grow significantly on ordinary aerobic culture media. We experienced a case of pneumonia and empyema caused by Streptococcus intermedius detected using a 16S rRNA gene sequencing analysis of bronchoalveolar lavage fluid and pleural effusion, but not sputum. Even when applying the molecular method, sputum samples are occasionally unsuitable for identifying the causative pathogens of lower respiratory tract infections.
authors.affiliation: Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan.
authors.forename: Shingo
authors.initials: S
authors.lastname: Noguchi
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yatera
authors.forename: Toshinori
authors.initials: T
authors.lastname: Kawanami
authors.forename: Kei
authors.initials: K
authors.lastname: Yamasaki
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Fukuda
authors.forename: Keisuke
authors.initials: K
authors.lastname: Naito
authors.forename: Kentarou
authors.initials: K
authors.lastname: Akata
authors.forename: Shuya
authors.initials: S
authors.lastname: Nagata
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishimoto
authors.forename: Hatsumi
authors.initials: H
authors.lastname: Taniguchi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mukae
mesh_terms: D000368:Aged; D016724:Empyema, Pleural / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D008297:Male; D064307:Microbiota / Q000502:physiology*; D018410:Pneumonia, Bacterial / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D012141:Respiratory Tract Infections / Q000150:complications / Q000175:diagnosis / Q000382:microbiology; D013290:Streptococcal Infections / Q000150:complications / Q000175:diagnosis*; D034367:Streptococcus intermedius / Q000302:isolation & purification*