title: Vitamin D and prostate cancer survival in veterans.
abstract: Prostate cancer remains the second most commonly diagnosed cancer among the male population worldwide. Vitamin D deficiency has been linked to prostate cancer and its aggressiveness. Herein, we initiated a retrospective study to evaluate vitamin D status and monitoring in veterans with prostate cancer, and to examine the potential link between vitamin D and survival status and length of survival in this population. We found that veterans who were initially vitamin D deficient were significantly less likely to survive than those who were not initially deficient, and that both initial and follow-up vitamin D deficiency were associated with decreased likelihood of survival after prostate cancer diagnosis. We recommend that vitamin D deficiency be replaced in veterans with prostate cancer.
authors.affiliation: Department of Internal Medicine, East Tennessee State University, P.O. Box 70622, Johnson City, TN 37614.
authors.forename: Tatyana
authors.initials: T
authors.lastname: Der
authors.affiliation: Department Family Medicine, East Tennessee State University, P.O. Box 70621, Johnson City, TN 37614.
authors.forename: Beth A
authors.initials: BA
authors.lastname: Bailey
authors.affiliation: Department of Internal Medicine, East Tennessee State University, P.O. Box 70622, Johnson City, TN 37614.
authors.forename: Dima
authors.initials: D
authors.lastname: Youssef
authors.affiliation: Mountain Home VAMC, Mountain Home, TN 37684.
authors.forename: Todd
authors.initials: T
authors.lastname: Manning
authors.affiliation: Sunlight, Nutrition and Health Research Center, P.O. Box 641603, San Francisco, CA 94164-1603.
authors.forename: William B
authors.initials: WB
authors.lastname: Grant
authors.affiliation: Department of Internal Medicine, East Tennessee State University, P.O. Box 70622, Johnson City, TN 37614.
authors.forename: Alan N
authors.initials: AN
authors.lastname: Peiris
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000097:blood* / Q000401:mortality*; D012189:Retrospective Studies; D015996:Survival Rate; D014481:United States / Q000453:epidemiology; D014728:Veterans; D014807:Vitamin D / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood*; D014815:Vitamins / Q000008:administration & dosage
chemical_list: D014815:Vitamins; D014807:Vitamin D; C104450:25-hydroxyvitamin D