title: Isolated limb infusion: technical aspects.
abstract: OBJECTIVE
  To describe the technique of isolated limb infusion (ILI) for regional high dose chemotherapy in patients with advanced malignancies confined to a limb, as currently practiced at Melanoma Institute Australia (MIA).
  
  
  BACKGROUND
  ILI is progressively being used around the world but to date the reported response rates are generally lower than those reported by MIA.
  
  
  CONCLUSIONS
  This description of the ILI protocol at MIA provides details that may allow other surgeons to improve results.
authors.affiliation: Melanoma Institute Australia, Sydney, NSW, Australia.
authors.forename: Hidde M
authors.initials: HM
authors.lastname: Kroon
authors.forename: Annemarleen
authors.initials: A
authors.lastname: Huismans
authors.forename: Richard C
authors.initials: RC
authors.lastname: Waugh
authors.forename: Peter C A
authors.initials: PC
authors.lastname: Kam
authors.forename: John F
authors.initials: JF
authors.lastname: Thompson
mesh_terms: D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods*; D006801:Humans; D008545:Melanoma / Q000098:blood supply / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D009362:Neoplasm Metastasis
keywords: in transit metastasis; isolated limb infusion; melanoma; soft tissue sarcoma; toxicity