title: Highly diastereoselective cyclopropanation of α-methylstyrene catalysed by a C2-symmetrical chiral iron porphyrin complex.
abstract: A new chiral iron porphyrin-based catalyst performed α-methylstyrene stereoselective cyclopropanation with excellent yields (up to 99%), enantio- and diastereoselectivities (ee(trans) up to 87%, trans/cis ratios up to 99 : 1) and outstanding TON and TOF values (up to 20,000 and 120,000 h(-1) respectively).
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy. emma.gallo@unimi.it.
authors.forename: Daniela
authors.initials: D
authors.lastname: Intrieri
authors.forename: Stéphane
authors.initials: S
authors.lastname: Le Gac
authors.forename: Alessandro
authors.initials: A
authors.lastname: Caselli
authors.forename: Eric
authors.initials: E
authors.lastname: Rose
authors.forename: Bernard
authors.initials: B
authors.lastname: Boitrel
authors.forename: Emma
authors.initials: E
authors.lastname: Gallo
mesh_terms: D002384:Catalysis; D003521:Cyclopropanes / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D008665:Metalloporphyrins / Q000737:chemistry*; D013237:Stereoisomerism; D013343:Styrenes / Q000737:chemistry*; D013379:Substrate Specificity
chemical_list: D003521:Cyclopropanes; D008665:Metalloporphyrins; D013343:Styrenes; C017915:alpha-methylstyrol; D007501:Iron