title: Histopathological, immunophenotypic and clinical particularities and evolution of a case of hepatosplenic T-cell lymphoma in transformation to leukemia.
abstract: We present the possibilities of diagnosis correlating the pathological, immunophenotyping and clinical aspects of a rare case of T-cell lymphoma in a 23-year-old patient with leukemic transformation. In our consideration, it is very important to describe this case because in the literature there are very few cases presented and the treatment of this type of lymphoma does not present optimal results, the evolution of the patients being from three months to two years. The treatment modality that gives the possibility to prolong survival and cure is hematopoietic stem cell transplantation.
authors.affiliation: Department of Pathology, Faculty of General Medicine, University of Medicine and Pharmacy of Tirgu Mures, Romania; horvath_emoke@yahoo.com.
authors.forename: Erzsébet
authors.initials: E
authors.lastname: Benedek Lázár
authors.forename: Judit Beáta
authors.initials: JB
authors.lastname: Köpeczi
authors.forename: Aliz Beáta
authors.initials: AB
authors.lastname: Tunyogi
authors.forename: Enikő
authors.initials: E
authors.lastname: Kakucs
authors.forename: Emőke
authors.initials: E
authors.lastname: Horváth
authors.forename: M
authors.initials: M
authors.lastname: Turcu
authors.forename: I
authors.initials: I
authors.lastname: Benedek
mesh_terms: D001853:Bone Marrow / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D018450:Disease Progression; D006801:Humans; D016130:Immunophenotyping; D007938:Leukemia / Q000473:pathology*; D008113:Liver Neoplasms / Q000175:diagnosis / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D013154:Spleen / Q000473:pathology; D013160:Splenic Neoplasms / Q000175:diagnosis / Q000473:pathology*; D055815:Young Adult