title: Anesthetic gases and occupationally exposed workers.
abstract: The aim of this study is to estimate whether the occupational exposure to low dose anesthetic gases could cause alterations of blood parameters in health care workers. 119 exposed subjects and 184 not exposed controls were included in the study. Each worker underwent the complete blood count test (CBC), proteinaemia, leukocyte count, serum lipids, liver and kidney blood markers. The liver blood markers show statistically significant differences in health care workers compared with controls (p<0.05), a statistically significant decrease in neutrophils and an increase of lymphocytes in health care workers compared with controls (p<0.05). The prevalence of values outside the range for GPT, GGT, total bilirubin, lymphocytes and neutrophils was statistically significant in health care workers compared with controls (p<0.05). The results suggest that occupational exposure to low dose anesthetic gases could influence some haematochemical hepatic and hematopoietic parameters in exposed health care workers.
authors.affiliation: Department of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine, University of Rome "Sapienza", Viale Regina Elena 336, 00161 Rome, Italy. Electronic address: info@spinoff-sipro.it.
authors.forename: Teodorico
authors.initials: T
authors.lastname: Casale
authors.affiliation: Department of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine, University of Rome "Sapienza", Viale Regina Elena 336, 00161 Rome, Italy.
authors.forename: Tiziana
authors.initials: T
authors.lastname: Caciari
authors.affiliation: Department of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine, University of Rome "Sapienza", Viale Regina Elena 336, 00161 Rome, Italy.
authors.forename: Maria Valeria
authors.initials: MV
authors.lastname: Rosati
authors.affiliation: Department of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine, University of Rome "Sapienza", Viale Regina Elena 336, 00161 Rome, Italy.
authors.forename: Pier Agostino
authors.initials: PA
authors.lastname: Gioffrè
authors.affiliation: Department of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine, University of Rome "Sapienza", Viale Regina Elena 336, 00161 Rome, Italy.
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: Schifano
authors.affiliation: Department of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine, University of Rome "Sapienza", Viale Regina Elena 336, 00161 Rome, Italy.
authors.forename: Assunta
authors.initials: A
authors.lastname: Capozzella
authors.affiliation: Department of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine, University of Rome "Sapienza", Viale Regina Elena 336, 00161 Rome, Italy.
authors.forename: Benedetta
authors.initials: B
authors.lastname: Pimpinella
authors.affiliation: Department of Psychiatric and Psychological Science, University of Rome "Sapienza", Piazzale Aldo Moro 5, 00185 Rome, Italy.
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Tomei
authors.affiliation: Department of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine, University of Rome "Sapienza", Viale Regina Elena 336, 00161 Rome, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Tomei
mesh_terms: D000328:Adult; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D001663:Bilirubin / Q000097:blood; D001772:Blood Cell Count; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008055:Lipids / Q000097:blood; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000187:drug effects; D016273:Occupational Exposure / Q000009:adverse effects*; D009873:Operating Rooms; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D018685:Anesthetics, Inhalation; D008055:Lipids; D005723:gamma-Glutamyltransferase; D001663:Bilirubin
keywords: Anesthetic gases; Health care workers; Hematological parameters