title: Prolonged Cholestatic Jaundice Associated With Flurbiprofen.
abstract: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely consumed drugs throughout the world for pain relief. Although the adverse effects of NSAIDs to the liver are well known, flurbiprofen-induced liver cholestasis is extremely rare. Herein, we present a patient with prolonged icterus that is associated with the use of flurbiprofen without causing ductopenia.
authors.affiliation: Erciyes University, Medical School, Department of Gastroenterology, Kayseri, Turkey serkanmd2004@yahoo.com.
authors.forename: Serkan
authors.initials: S
authors.lastname: Dogan
authors.affiliation: Bozok University, Medical School, Department of Gastroenterology, Yozgat, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Celikbilek
authors.affiliation: Hacettepe University, Medical School, Department of Pharmacology, Ankara, Turkey.
authors.forename: Kutay
authors.initials: K
authors.lastname: Demirkan
authors.affiliation: Erciyes University, Medical School, Department of Internal Medicine, Kayseri, Turkey.
authors.forename: Semih
authors.initials: S
authors.lastname: Yilmaz
authors.affiliation: Erciyes University, Medical School, Department of Pathology, Kayseri, Turkey.
authors.forename: Kemal
authors.initials: K
authors.lastname: Deniz
authors.affiliation: Erciyes University, Medical School, Department of Gastroenterology, Kayseri, Turkey.
authors.forename: Sebnem
authors.initials: S
authors.lastname: Gursoy
authors.affiliation: Erciyes University, Medical School, Department of Gastroenterology, Kayseri, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yucesoy
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology / Q000473:pathology; D005480:Flurbiprofen / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D041781:Jaundice, Obstructive / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D013997:Time Factors
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005480:Flurbiprofen
keywords: cholestatic; drug information; flurbiprofen; hepatitis; liver injury; medication safety