title: Evaluation of the FIRI (Fasting Insulin Resistance Index) and selected plasma parameters associated with insulin resistance as predictors of cardiovascular mortality in rural Chinese women.
abstract: Insulin Resistance Syndrome (IRS) refers to a cluster of pathologies including hypercholesterolaemia, diabetes, hypertension and cardiovascular disease indicating that these diseases share a common aetiology in insulin resistance and hyperinsulinaemia. Recently a simple index of insulin resistance referred to as the Fasting Insulin Resistance Index (FIRI) was proposed by Duncan et al, for use in clinical practice and epidemiologic investigations of disease FIRI is estimated as the product of fasting plasma glucose and fasting plasma insulin divided by 25 (FIRI = (glucose x insulin/25). This communication evaluates the utility of FIRI using data from a large comprehensive ecologic study on diet and disease in rural counties in the People's Republic of China and provides support for the use of this biomarker/index in epidemiologic studies on disease states associated with IRS.
authors.affiliation: Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Gates
authors.forename: B
authors.initials: B
authors.lastname: Parpia
authors.forename: T C
authors.initials: TC
authors.lastname: Campbell
authors.forename: J
authors.initials: J
authors.lastname: Chen