title: Epicardial adipose tissue thickness in hemodialysis patients.
abstract: OBJECTIVE
  Hemodialysis (HD) patients had higher cardiovascular mortality and it is related to atherosclerosis. Epicardial adipose tissue (EAT) thickness is a marker of atherosclerosis and independent predictor of coronary artery disease. The aim of our study was to evaluate the relationship between EAT and carotid intima-media thickness (CIMT) predictors of early atherosclerosis in HD patients.
  
  
  METHODS
  The study included 62 HD patients and 40 healthy controls. EAT thickness and CIMT were measured by echocardiography in all subjects.
  
  
  RESULTS
  Epicardial adipose tissue thickness and CIMT were higher (6.98 ± 1.67 vs. 3.84 ± 0.73 mm, P < 0.001, 0.94 ± 0.17 vs. 0.63 ± 0.11 mm, P < 0.001, respectively) in HD patients than in control subjects. EAT thickness were correlated with CIMT, HD duration, age, and calcium. In addition, HD duration, CIMT, and age were independent predictors of EAT thickness on HD patients in regression analysis.
  
  
  CONCLUSIONS
  Epicardial adipose tissue thickness may be a useful indicator of early atherosclerosis in HD patients.
authors.affiliation: Department of Cardiology, Canakkale Onsekiz Mart University, Canakkale, Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Altun
authors.forename: Hakan
authors.initials: H
authors.lastname: Tasolar
authors.forename: Necmi
authors.initials: N
authors.lastname: Eren
authors.forename: Emine
authors.initials: E
authors.lastname: Binnetoğlu
authors.forename: Mehzat
authors.initials: M
authors.lastname: Altun
authors.forename: Ahmet
authors.initials: A
authors.lastname: Temiz
authors.forename: Emine
authors.initials: E
authors.lastname: Gazi
authors.forename: Ahmet
authors.initials: A
authors.lastname: Barutcu
authors.forename: Orcun
authors.initials: O
authors.lastname: Altunoren
authors.forename: Yucel
authors.initials: Y
authors.lastname: Colkesen
authors.forename: Fatma
authors.initials: F
authors.lastname: Uysal
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging*; D050154:Adiposity; D000328:Adult; D050197:Atherosclerosis / Q000000981:diagnostic imaging* / Q000209:etiology*; D059168:Carotid Intima-Media Thickness; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D010496:Pericardium / Q000000981:diagnostic imaging*; D011379:Prognosis; D006435:Renal Dialysis / Q000009:adverse effects*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
keywords: atherosclerosis; epicardial adipose tissue; hemodialysis