title: Molecular modelling of HLA-B*35:132.
abstract: Here we describe the molecular modelling of the new variant HLA-B*35:132. This allele shows one mismatch with B*35:01:01:01 in exon 3 at position 575 where a T is substituted by a C, which implies an amino acidic change from Leucine to Proline. This seems not to alter the molecular structure and not to compromise the HLA complex and T-cell receptor interaction.
authors.affiliation: Organ and Tissue Transplantation Immunology, Regenerative Medicine Department, Immunologia dei Trapianti di Organi e Tessuti, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Longhi
authors.forename: P
authors.initials: P
authors.lastname: Crivello
authors.forename: M
authors.initials: M
authors.lastname: Mantovani
authors.forename: S
authors.initials: S
authors.lastname: Frison
authors.forename: K
authors.initials: K
authors.lastname: Fleischhauer
authors.forename: L
authors.initials: L
authors.lastname: Crespiatico
authors.forename: G
authors.initials: G
authors.lastname: Piccolo
authors.forename: F
authors.initials: F
authors.lastname: Poli
mesh_terms: D000483:Alleles; D000595:Amino Acid Sequence; D001483:Base Sequence; D016026:Bone Marrow Transplantation; D003001:Cloning, Molecular; D005091:Exons; D015797:HLA-B35 Antigen / Q000235:genetics* / Q000276:immunology; D006650:Histocompatibility Testing; D006801:Humans; D008958:Models, Molecular; D008969:Molecular Sequence Data; D017354:Point Mutation; D040681:Structural Homology, Protein; D014019:Tissue Donors
chemical_list: D015797:HLA-B35 Antigen