title: Five-plex isotope dimethyl labeling for quantitative proteomics.
abstract: Stable isotope dimethyl labeling, a widely used method for quantitative proteomics, was extended to five channels for the first time. Comprehensive proteome and phosphoproteome quantification validated the high quantification accuracy and throughput of this five-plex method.
authors.affiliation: Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. wangfj@dicp.ac.cn hanfazou@dicp.ac.cn.
authors.forename: Yue
authors.initials: Y
authors.lastname: Wu
authors.forename: Fangjun
authors.initials: F
authors.lastname: Wang
authors.forename: Zheyi
authors.initials: Z
authors.lastname: Liu
authors.forename: Hongqiang
authors.initials: H
authors.lastname: Qin
authors.forename: Chunxia
authors.initials: C
authors.lastname: Song
authors.forename: Junfeng
authors.initials: J
authors.lastname: Huang
authors.forename: Yangyang
authors.initials: Y
authors.lastname: Bian
authors.forename: Xiaoluan
authors.initials: X
authors.lastname: Wei
authors.forename: Jing
authors.initials: J
authors.lastname: Dong
authors.forename: Hanfa
authors.initials: H
authors.lastname: Zou
mesh_terms: D029968:Escherichia coli Proteins / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D007553:Isotope Labeling / Q000379:methods*; D040901:Proteomics / Q000379:methods*
chemical_list: D029968:Escherichia coli Proteins