title: Centella asiatica in dermatology: an overview.
abstract: Centella asiatica is a medicinal plant that was already used as a 'panacea' 3000 years ago. The active compounds include pentacyclic triterpenes, mainly asiaticoside, madecasosside, asiatic acid and madecassic acid. We have conducted an overview to summarize current knowledge on the results of scientific in vitro and in vivo experiments focused on the improvement of the healing process of small wounds, hypertrophic scars and burns by C. asiatica. In this paper, we discuss the data on constituents, recommended preparations and the potential side effects of C. asiatica.
authors.affiliation: Department of Pharmacognosy, Poznan University of Medical Sciences, Święcickiego 4, 60-781, Poznań, Poland.
authors.forename: Wiesława
authors.initials: W
authors.lastname: Bylka
authors.forename: Paulina
authors.initials: P
authors.lastname: Znajdek-Awiżeń
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Studzińska-Sroka
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Dańczak-Pazdrowska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Brzezińska
mesh_terms: D000818:Animals; D028041:Centella / Q000737:chemistry*; D003880:Dermatology; D006801:Humans; D053978:Pentacyclic Triterpenes / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D012871:Skin Diseases / Q000188:drug therapy*; D014315:Triterpenes / Q000494:pharmacology*; D014945:Wound Healing / Q000187:drug effects*
chemical_list: C526146:Centella asiatica extract; D053978:Pentacyclic Triterpenes; D010936:Plant Extracts; D014315:Triterpenes; C017032:asiatic acid; C001669:madecassic acid; C004446:asiaticoside
keywords: Centella asiatica; dermatology; review; triterpenes