title: [Association between mesenteric phlebosclerosis and Chinese herbal medicine intake].
abstract: BACKGROUND
  Mesenteric phlebosclerosis (MP) is a relatively rare disease of the colon. An association between MP and Chinese herbal medicine intake has recently been recognized.
  
  
  METHODS
  In the present study, we investigated the association between MP and Chinese herbal medicine intake in 42 patients, including those reported in the literature as well as those treated by us.
  
  
  RESULTS
  Approximately 90% patients treated by us reported a history of Chinese herbal medicine intake, particularly kamishoyosan, orengedokuto, and sanshishi (gardeniae fructus), the lattermost being consumed by the majority of patients as a crude herbal medicine.
  
  
  CONCLUSIONS
  Several MP patients report a history of Chinese herbal medicine intake. Furthermore, symptoms are exacerbated in MP patients who continue to consume the medicine after onset. Interestingly, MP was reported to develop in a married couple who had consumed the same Chinese herbal medicine for a prolonged period. These findings suggest that the intake of Chinese herbal medicine, particularly sanshishi, is strongly associated with MP development.
authors.affiliation: Department of Gastroenterology, Fukuoka University Chikushi Hospital.
authors.forename: Kensei
authors.initials: K
authors.lastname: Ohtsu
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Matsui
authors.forename: Taku
authors.initials: T
authors.lastname: Nishimura
authors.forename: Fumihito
authors.initials: F
authors.lastname: Hirai
authors.forename: Keisuke
authors.initials: K
authors.lastname: Ikeda
authors.forename: Akinori
authors.initials: A
authors.lastname: Iwashita
authors.forename: Makoto
authors.initials: M
authors.lastname: Yorioka
authors.forename: Sadamune
authors.initials: S
authors.lastname: Hatakeyama
authors.forename: Toshio
authors.initials: T
authors.lastname: Hoashi
authors.forename: Yuki
authors.initials: Y
authors.lastname: Koga
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Sakurai
authors.forename: Masaki
authors.initials: M
authors.lastname: Miyaoka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004365:Drugs, Chinese Herbal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008642:Mesenteric Veins; D008875:Middle Aged; D012598:Sclerosis / Q000139:chemically induced
chemical_list: D004365:Drugs, Chinese Herbal