title: Probiotics and colon cancer prevention.
abstract: This review examines some of the evidence regarding probiotic bacteria as agents to reduce the risk of colon cancer in humans. While some of the evidence using rodent models of colon cancer is convincing for a reduction in cancer incidence and burden with the introduction orally of such bacteria as Bifidobacterium longum, Lactobacillus acidophilus and gg, convincing evidence in humans is more difficult to find. It consists of epidemiological studies or marker intervention studies using faecal enzymes, faecal bile acids or urinary/ faecal mutagens from microbial activity as measures of cancer risk, following probiotic introduction. Taken together these sources of data provide limited support for the hypothesis that probiotic bacteria are effective in cancer prevention.
authors.affiliation: CSIRO Division of Human Nutrition.
authors.forename: G H
authors.initials: GH
authors.lastname: McIntosh