title: Percutanous closure of left ventricular aneurysms in a patient with Loeys-Dietz syndrome.
abstract: We report a case of percutaneous closure of multiple left ventricular aneurysms in a patient with inherited aortic-aneurysm syndrome-the Loeys-Dietz syndrome. One aneurysm was a true aneurysm in the subaortic region and the second one was a pseudoaneurysm at the left ventricular apex. The patient was a high-risk candidate for repeated operations. Both aneurysms were closed successfully percutaneously in staged procedures. There were no complications. The patient remained clinically well with stable echocardiographic results upon reassessment. This case illustrated that catheter-based closure of left ventricular aneurysms is a feasible approach in the context of connective tissue abnormalities related to the Loeys-Dietz syndrome.
authors.affiliation: CardioVascular Center Frankfurt, Frankfurt, Germany.
authors.forename: Simon Cheung
authors.initials: SC
authors.lastname: Chi Lam
authors.forename: Stefan
authors.initials: S
authors.lastname: Bertog
authors.forename: Horst
authors.initials: H
authors.lastname: Sievert
mesh_terms: D017541:Aneurysm, False / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006328:Cardiac Catheterization / Q000295:instrumentation; D062906:Cardiac Catheters; D018618:Echocardiography, Doppler, Color; D004867:Equipment Design; D006322:Heart Aneurysm / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D055947:Loeys-Dietz Syndrome / Q000150:complications* / Q000175:diagnosis; D008297:Male; D015641:Radiography, Interventional; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
keywords: Loeys-Dietz syndrome; connective tissue disease; percutaneous left ventricular aneurysmal closure