title: Rhodium-catalyzed three-component reaction of 3-diazooxindoles with indoles and isatin-derived ketimines: a facile and versatile approach to functionalized 3,3',3''-trisindoles.
abstract: A simple, facile and efficient Rh2(OAc)4-catalyzed three-component reaction of 3-diazooxindoles with indoles and isatin-derived N-Boc ketimines towards a variety of functionalized 3,3',3''-trisindoles in high yields with moderate to excellent diastereoselectivities has been developed. This methodology provides an ideal approach for the direct introduction of indole and oxindole into an isatin moiety at the 3-position.
authors.affiliation: Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China.
authors.forename: Liang-Yong
authors.initials: LY
authors.lastname: Mei
authors.forename: Xiang-Ying
authors.initials: XY
authors.lastname: Tang
authors.forename: Min
authors.initials: M
authors.lastname: Shi
mesh_terms: D001391:Azo Compounds / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D007097:Imines / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001391:Azo Compounds; D007097:Imines; D007211:Indoles; D009570:Nitriles; D009942:Organometallic Compounds; C542835:ketimine; D012238:Rhodium