title: Successful treatment of pure red cell aplasia and autoimmune cytopenia with cyclosporine and prednisolone in a patient with Sjögren's syndrome.
abstract: Abstract A 68-year-old woman was admitted to our hospital with xerophthalmia, xerostomia, leukopenia, and thrombocytopenia. She was diagnosed to have Sjögren's syndrome and autoimmune cytopenia. After 11 months, she was readmitted with severe anemia and reticulocytopenia. Mild hemolysis was seen, and bone marrow aspirate showed markedly decreased erythropoiesis. An association of pure red cell aplasia (PRCA) and autoimmune hemolytic anemia was diagnosed. After treatment with cyclosporine and prednisolone, her anemia dramatically improved. We discuss the mechanism of PRCA associated with Sjögren's syndrome.
authors.affiliation: Department of Rheumatology and Medicine, Medical Institute of Bioregulation, Kyushu University , 4546 Tsurumihara, Beppu 874-0838 , Japan.
authors.forename: Motoaki
authors.initials: M
authors.lastname: Shiratsuchi
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Kitamura
authors.forename: Youko
authors.initials: Y
authors.lastname: Suehiro
authors.forename: Susumu
authors.initials: S
authors.lastname: Taniguchi
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Sakai
authors.forename: Takashi
authors.initials: T
authors.lastname: Sugimura
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Fukutomi
authors.forename: Yasuji
authors.initials: Y
authors.lastname: Yoshikawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Shiokawa
authors.forename: Shoichiro
authors.initials: S
authors.lastname: Ikuyama
authors.forename: Junji
authors.initials: J
authors.lastname: Nishimura