title: Quality of life in patients with psychotic disorders: impact of symptoms, personality, and attachment.
abstract: The aims of this study were to assess the relative contribution of symptoms and specific psychosocial factors to different domains of quality of life (QoL) in patients with psychotic disorders. Positive, negative, and depressive symptoms; Five-Factor Model personality traits; and attachment dimensions were assessed in 110 patients with nonaffective psychotic disorders. Hierarchical and stepwise regression analyses were conducted. Psychosocial factors were able to predict all domains of QoL, when symptom severity was controlled for. Furthermore, the physical QoL domain was best predicted by attachment, personality, and sex (R = 43.1%); the psychological QoL domain, by personality and depressive symptoms (R = 60.5%); the social domain, by personality and positive symptoms (R = 30.3%); and the environmental domain, by personality and negative symptoms (R = 27.9%). Our findings highlight the role that specific individual characteristics play in different aspects of QoL in patients with psychotic disorders.
authors.affiliation: Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Lindy-Lou
authors.initials: LL
authors.lastname: Boyette
authors.forename: Nikie
authors.initials: N
authors.lastname: Korver-Nieberg
authors.forename: Carin
authors.initials: C
authors.lastname: Meijer
authors.forename: Lieuwe
authors.initials: L
authors.lastname: de Haan
mesh_terms: D000328:Adult; D000368:Aged; D003863:Depression / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009769:Object Attachment; D010551:Personality; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000523:psychology*; D011788:Quality of Life; D012565:Schizophrenic Psychology; D012720:Severity of Illness Index