title: Sympathetic neural regulation of blood pressure: influences of sex and aging.
abstract: Sex and age have important influences on sympathetic neural control of blood pressure in humans. Young women are relatively protected against risk of hypertension due to greater peripheral vasodilator influences compared with young men and older people. This protective effect is lost at menopause. Older men and women have higher sympathetic nerve activity and tighter coupling between SNA and blood pressure, contributing to the increased risk of hypertension with aging.
authors.affiliation: School of Physiology and Pharmacology, University of Bristol, Bristol, United Kingdom; and.
authors.forename: E C J
authors.initials: EC
authors.lastname: Hart
authors.forename: N
authors.initials: N
authors.lastname: Charkoudian
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D012727:Sex Characteristics; D013564:Sympathetic Nervous System / Q000502:physiology*