title: [Research development of amniotic fluid-derived stem cells in regenerative medicine].
abstract: OBJECTIVE
  To review the latest development of amniotic fluid-derived stem cells (AFSCs) in regenerative medicine, and to discuss issues related to the studies in the field of AFSCs.
  
  
  METHODS
  The recent articles about AFSCs were extensively reviewed. The important knowledge of AFSCs was introduced in the field of regenerative medicine, and the basic and clinical researches of AFSCs were summarized and discussed.
  
  
  RESULTS
  Currently, it is confirmed that AFSCs have a multi-directional differentiation capacity, therefore, they have a wide application prospect in regenerative medicine, anti-tumor, and other fields.
  
  
  CONCLUSIONS
  AFSCs will become one of the ideal seed cells in the field of regenerative medicine with extensive research value because of the advantages of easy amniotic fluid sampling, little maternal and child trauma, no tumorigenesis, and no ethical restrictions.
authors.affiliation: Department of Pediatric Surgery, First Affiliated Hospital of Anhui Medical University, Hefei Anhui 230022, PR China.
authors.forename: Chun
authors.initials: C
authors.lastname: Li
authors.affiliation: Department of Pediatric Surgery, First Affiliated Hospital of Anhui Medical University, Hefei Anhui 230022, PR China.
authors.forename: Weisong
authors.initials: W
authors.lastname: Li
authors.affiliation: Department of Pediatric Surgery, First Affiliated Hospital of Anhui Medical University, Hefei Anhui 230022, PR China.
authors.forename: Hu
authors.initials: H
authors.lastname: Liu
authors.affiliation: Department of Dermatology, Fourth Affiliated Hospital of Anhui Medical University, PR China.
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
mesh_terms: D000653:Amniotic Fluid / Q000166:cytology*; D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D002478:Cells, Cultured; D006801:Humans; D009928:Organ Specificity; D012038:Regeneration / Q000502:physiology*; D044968:Regenerative Medicine / Q000379:methods*; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology; D023822:Tissue Engineering / Q000379:methods*