title: [Long-term survival of a case with advanced sigmoid colon cancer and Virchow's lymph node metastasis].
abstract: A 63-year-old man presented with a tumor in his left supraclavicular fossa. Aspiration biopsy of the tumor revealed metastasis of an adenocarcinoma. Further examination indicated the presence of advanced sigmoid colon cancer with metastases to Virchow's lymph nodes and the para-aortic lymph nodes. Sigmoidectomy with D3 lymph node dissection was performed. Histological examination revealed moderately and well differentiated adenocarcinomas( double cancers) that had invaded the subserosa as well as metastases of the para-aortic lymph nodes. Twelve days after the operation, systemic chemotherapy with FOLFOX4 (8 courses), followed by FOLFIRI (8 courses) was administered. Six months later, CT examination determined that the metastases of Virchow's lymph nodes and the para-aortic lymph nodes had completely disappeared. Capecitabine was administered for approximately 1 year, and complete response was achieved. However, a pancreatic tumor measuring 2×3 cm was detected 44 months after the operation. Distal pancreatectomy was performed and pathological examination that included immunohistochemical staining (CK7 and CK20) of the tumor indicated the primary pancreatic cancer. The patient was treated with chemoradiotherapy after the operation and survived for 5 years and 9 months after the initial operation.
authors.affiliation: Dept. of Surgery, Tokyo Metropolitan Health and Medical Treatment Corporation Toshima Hospital.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ando
authors.forename: Keiichi
authors.initials: K
authors.lastname: Fujiya
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Kamikozuru
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ganno
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Amagasa
authors.forename: Shoko
authors.initials: S
authors.lastname: Takeuchi
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Kawai
authors.forename: Akira
authors.initials: A
authors.lastname: Fukuda
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nagahama
authors.forename: Katsunori
authors.initials: K
authors.lastname: Ami
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Aoki
authors.forename: Kuniyoshi
authors.initials: K
authors.lastname: Arai
authors.forename: Shikofumi
authors.initials: S
authors.lastname: Tei
authors.forename: Youichi
authors.initials: Y
authors.lastname: Okada
authors.forename: Kinji
authors.initials: K
authors.lastname: Miura
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery*; D011379:Prognosis; D012811:Sigmoid Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D013997:Time Factors