title: Systemic treatment with isotretinoin suppresses itraconazole blood level in chronic granulomatous disease.
authors.affiliation: Department of Pediatric Pneumology and Immunology, Charité Hospital - Humboldt University, Berlin, Germany; Fachbereich Immunologie, Labor Berlin Charité Vivantes GmbH, Berlin, Germany.
authors.forename: Horst
authors.initials: H
authors.lastname: von Bernuth
authors.forename: Volker
authors.initials: V
authors.lastname: Wahn
mesh_terms: D000152:Acne Vulgaris / Q000209:etiology / Q000517:prevention & control*; D000328:Adult; D019072:Antibiotic Prophylaxis; D000908:Antibodies, Fungal / Q000097:blood; D000935:Antifungal Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics; D001228:Aspergillosis / Q000209:etiology / Q000517:prevention & control*; D004347:Drug Interactions; D006105:Granulomatous Disease, Chronic / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D015474:Isotretinoin / Q000008:administration & dosage* / Q000009:adverse effects; D017964:Itraconazole / Q000008:administration & dosage* / Q000493:pharmacokinetics; D007641:Keratolytic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D055815:Young Adult
chemical_list: D000908:Antibodies, Fungal; D000935:Antifungal Agents; D007641:Keratolytic Agents; D017964:Itraconazole; D015474:Isotretinoin