title: Amine-catalyzed asymmetric cross-aldol reactions using heterofunctionalized acetaldehydes as nucleophiles.
abstract: Various heterofunctionalized acetaldehydes were successfully employed in an amine-catalyzed asymmetric cross-aldol reaction, affording a variety of synthetically useful 1,2-difunctionalized compounds such as 1,2-diols and 1,2-aminoalcohols. With this method, both syn- and anti-1,2-difunctionalized compounds were obtained from the same set of reactants by using the appropriate amine catalyst.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University , Sakyo, Kyoto 606-8502, Japan.
authors.forename: Taichi
authors.initials: T
authors.lastname: Kano
authors.forename: Ryu
authors.initials: R
authors.lastname: Sakamoto
authors.forename: Keiji
authors.initials: K
authors.lastname: Maruoka