title: An evidence for lack of pseudoneglect in patients with schizophrenia: an ERP study.
abstract: Studies have reported an altered expression of pseudoneglect in patients with schizophrenia, but no study has examined pseudoneglect in schizophrenia at the neural level. We investigated pseudoneglect using the visual P3 event-related potential and the mental number bisection (MNB) task in 21 patients and 25 controls. Using an oddball task, participants were asked to discriminate an infrequent ('one' or 'nine') from a frequent written number ('five'). The P3 ERP components were delayed to the targets on the right of the MNL ('nine') compared to the targets on the left ('one') in controls. The effect of number magnitude on the P3 latency was not observed in the patients. In MNB task, the patients did not show the normal leftward bias observed in healthy individuals. Our findings indicate a lack of pseudoneglect and the presence of an anomalous brain asymmetry in schizophrenia.
authors.affiliation: Neuroscience Research Centre, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
authors.forename: Ali Mohammad
authors.initials: AM
authors.lastname: Pourrahimi
authors.affiliation: Neuroscience Research Centre, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran. Electronic address: smazhari@kmu.ac.ir.
authors.forename: Shahrzad
authors.initials: S
authors.lastname: Mazhari
authors.affiliation: Neuroscience Research Centre, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Shabani
authors.affiliation: Neuroscience Research Centre, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
authors.forename: Vahid
authors.initials: V
authors.lastname: Sheibani
mesh_terms: D000328:Adult; D001288:Attention; D016022:Case-Control Studies; D005074:Evoked Potentials, Visual; D006801:Humans; D008297:Male; D010468:Perceptual Disorders / Q000503:physiopathology*; D010775:Photic Stimulation; D012559:Schizophrenia / Q000503:physiopathology*; D012565:Schizophrenic Psychology
keywords: Oddball task; Pseudoneglect; Schizophrenia