title: A universal spring-probe system for reliable probing of electrochemical lab-on-a-chip devices.
abstract: For achieve sensitivity in lab-on-a-chip electrochemical detection, more reliable probing methods are required, especially for repeated measurements. Spring-probes are a promising candidate method which can replace needle-like probes and alligator clips that usually produce scratches on the surface of gold electrodes due to the strong physical contacts needed for electrochemical measurements. The superior reliability of amperometric measurements by a spring-probe system was compared with results by conventional probing methods. We demonstrated that a universal spring-probe system would be potentially suitable to achieve high performance in lab-on-a-chip devices using electrochemical detection.
authors.affiliation: Center for Nanobio Integration & Convergence Engineering, National Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon 305-806, Korea. mklee@nnfc.re.kr.
authors.forename: Moon-Keun
authors.initials: MK
authors.lastname: Lee
authors.affiliation: Center for Nanobio Integration & Convergence Engineering, National Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon 305-806, Korea. tjlee@nnfc.re.kr.
authors.forename: Tae Jae
authors.initials: TJ
authors.lastname: Lee
authors.affiliation: Center for Nanobio Integration & Convergence Engineering, National Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon 305-806, Korea. hwchoi@nnfc.re.kr.
authors.forename: Ho Woon
authors.initials: HW
authors.lastname: Choi
authors.affiliation: Center for Nanobio Integration & Convergence Engineering, National Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon 305-806, Korea. sjshin@nnfc.re.kr.
authors.forename: Su Jeong
authors.initials: SJ
authors.lastname: Shin
authors.affiliation: Center for Nanobio Integration & Convergence Engineering, National Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon 305-806, Korea. genome@korea.kr.
authors.forename: Jung Youn
authors.initials: JY
authors.lastname: Park
authors.affiliation: Center for Nanobio Integration & Convergence Engineering, National Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon 305-806, Korea. sjlee@nnfc.re.kr.
authors.forename: Seok Jae
authors.initials: SJ
authors.lastname: Lee
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D055664:Electrochemical Techniques / Q000295:instrumentation / Q000379:methods*; D006046:Gold / Q000737:chemistry; D006801:Humans; D056656:Lab-On-A-Chip Devices; D046210:Microfluidic Analytical Techniques / Q000379:methods*
chemical_list: D006046:Gold