title: Non-motor symptoms of Parkinson's disease A review…from the past.
abstract: Although Parkinson's disease (PD) has been classically defined as a motor disorder, a range of non-motor symptoms (NMS) including cognitive, mood, autonomic and sleep disturbances occur with the passage of time. Although it seems that the non-motor aspect of PD is a recent observation, classic authors (James Parkinson, Charcot, Gowers, Oppenheim and Wilson) had described many NMS including pain, fatigue, bladder dysfunction, cognitive decline and delusion. In this review we have collated the classic literature of NMS in PD.
authors.affiliation: Department of Neurology, Fundacion Jimenez Diaz, Madrid, Spain.
authors.forename: Pedro J
authors.initials: PJ
authors.lastname: Garcia-Ruiz
authors.affiliation: National Parkinson Foundation Centre of Excellence, King's College Hospital, King's College, London, UK.
authors.forename: K Ray
authors.initials: KR
authors.lastname: Chaudhuri
authors.affiliation: Alzheimer Center Reina Sofia Foundation, Carlos III Institute of Health, Madrid, Spain; CIBERNED, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Martinez-Martin
mesh_terms: D003072:Cognition Disorders / Q000209:etiology / Q000266:history; D003702:Delusions / Q000209:etiology / Q000266:history; D005221:Fatigue / Q000209:etiology / Q000266:history; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D010146:Pain / Q000209:etiology / Q000266:history; D010300:Parkinson Disease / Q000266:history* / Q000503:physiopathology*; D001745:Urinary Bladder Diseases / Q000209:etiology / Q000266:history
keywords: Classic literature; History of Neurology; Motor and non-motor evaluation; Non-motor symptoms; Pain; Parkinson's disease