title: Incredible antibacterial activity of noble metal functionalized magnetic core-zeolitic shell nanostructures.
abstract: Functionalized magnetic core-zeolitic shell nanostructures were prepared by hydrothermal and coprecipitation methods. The products were characterized by Vibrating Sample Magnetometer (VSM), X-ray powder diffraction (XRD), Fourier Transform Infrared (FTIR) spectra, nitrogen adsorption-desorption isotherms, and Transmission Electron Microscopy (TEM). The growth of mordenite nanoparticles on the surface of silica coated nickel ferrite nanoparticles in the presence of organic templates was also confirmed. Antibacterial activity of the prepared nanostructures was investigated by the inactivation of Escherichia coli as a gram negative bacterium. A new mechanism was proposed for inactivation of E. coli over the prepared samples. In addition, the Minimum Inhibitory Concentration (MIC) and reuse ability were studied. TEM images of the destroyed cell wall after the treatment time were performed to illustrate the inactivation mechanism. According to the experimental results, the core-shell nanostructures which were modified by organic agents and then functionalized with noble metal nanoparticles were the most active. The interaction of the noble metals with the organic components on the surface of nanostructures was studied theoretically and the obtained results were used to interpret the experimental results.
authors.affiliation: Department of Chemistry, Sharif University of Technology, Azadi Ave., Tehran, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Padervand
authors.affiliation: Department of Water Engineering, Tehran University, Karaj, Iran.
authors.forename: S
authors.initials: S
authors.lastname: Janatrostami
authors.affiliation: Department of Chemistry, Sharif University of Technology, Azadi Ave., Tehran, Iran.
authors.forename: A Kiani
authors.initials: AK
authors.lastname: Karanji
authors.affiliation: Department of Chemistry, Sharif University of Technology, Azadi Ave., Tehran, Iran. Electronic address: gholami@sharif.edu.
authors.forename: M R
authors.initials: MR
authors.lastname: Gholami
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects / Q000502:physiology; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D005290:Ferric Compounds / Q000737:chemistry* / Q000494:pharmacology*; D058185:Magnetite Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry*; D008422:Materials Testing; D009532:Nickel / Q000737:chemistry* / Q000494:pharmacology*; D017641:Zeolites / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D005290:Ferric Compounds; D058185:Magnetite Nanoparticles; C550717:nickel ferrite; D017641:Zeolites; D009532:Nickel
keywords: Antibacterial activity; E. coli; Magnetic core–zeolitic shell nanostructure; Mordenite; Nickel ferrite