title: Effect of metabolic inhibitors on growth and carotenoid production in Dunaliella bardawil.
abstract: Dunaliella bardawil, a green alga accumulates high amount of β-carotene under stress conditions. This organism has been exploited for β-carotene at industrial scale. In the present work, various metabolic inhibitors like diphenylamine (DPA), nicotine, basta, glyphosate, DCMU [3-(3',4'-dichlophenyl)-1,1-dimethylurea] and caffeine were used in autotrophic medium, to understand their influence on carotenoid biosynthesis. The results indicated that these metabolic inhibitors influenced the production of carotenoids like wise, DPA and basta increased the contents of β-carotene (1.7 fold), glyphosate and DCMU for lutein (2.4 and 2 fold) caffeine for biomass yields (1.1 fold), while nicotine decreased the biomass yield (3.6 fold), β-carotene (2 fold) and lutein (10.5 fold).
authors.affiliation: Plant Cell Biotechnology Department, Central Food Technological Research Institute, Council of Scientific and Industrial Research, Mysore, 570 020 Karnataka India.
authors.forename: Kavitha
authors.initials: K
authors.lastname: Mysore Doddaiah
authors.affiliation: Plant Cell Biotechnology Department, Central Food Technological Research Institute, Council of Scientific and Industrial Research, Mysore, 570 020 Karnataka India.
authors.forename: Anila
authors.initials: A
authors.lastname: Narayan
authors.affiliation: Plant Cell Biotechnology Department, Central Food Technological Research Institute, Council of Scientific and Industrial Research, Mysore, 570 020 Karnataka India.
authors.forename: Ravishankar
authors.initials: R
authors.lastname: Gokare Aswathanarayana
authors.affiliation: Plant Cell Biotechnology Department, Central Food Technological Research Institute, Council of Scientific and Industrial Research, Mysore, 570 020 Karnataka India.
authors.forename: Sarada
authors.initials: S
authors.lastname: Ravi
keywords: DCMU; Diphenylamine; Dunaliella bardawil; Glufosinate ammonium; Glyphosate; Lutein; Nicotine