title: Intralobar pulmonary sequestration complicating with cryptococcal infection.
abstract: BACKGROUND
  Pulmonary sequestration is a rare congenital malformation characterized by accessory lung tissue supplied by an aberrant systemic artery. It often presents with recurrent infections. But fungus infection is exceptional.
  
  
  OBJECTIVE
  To help other clinicians deal with patients with pulmonary sequestration complicating with cryptococcal infection.
  
  
  METHODS
  We reported a case of pulmonary sequestration complicating with pulmonary and eye cryptococcosis and did literature review.
  
  
  RESULTS
  A 20-year-old immunocompetent male patient suffered from eye pain and blurred vision, and received antibiotics and dexamethasone therapy with no improvement. Bacteriology inspection and computerized tomography scan indicated a diagnosis of cryptococcal infection in both eye and lung. Vitrectomy and antifungal agents were administered. Since symptoms fluctuations, lobectomy was operated. The surgery revealed the presence of pulmonary sequestration. Literature review showed that there is no report about pulmonary sequestration complicating with cryptococcal infection so far.
  
  
  CONCLUSIONS
  Pulmonary sequestration is a very important but extremely negligent cause for pulmonary cryptococcal infection.
authors.affiliation: Shanghai Institute of Respiratory Diseases, Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Guan
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.forename: Changzhou
authors.initials: C
authors.lastname: Shao
authors.forename: Lixian
authors.initials: L
authors.lastname: He
authors.forename: Yuanlin
authors.initials: Y
authors.lastname: Song
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001998:Bronchopulmonary Sequestration / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D003453:Cryptococcosis / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D015821:Eye Infections, Fungal / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D011013:Pneumonectomy; D055815:Young Adult
chemical_list: D000935:Antifungal Agents
keywords: cryptococcosis; endophthalmitis; lobectomy; pulmonary sequestration