title: Role of multiparametric magnetic resonance imaging in the diagnosis of prostate cancer.
abstract: Prostate cancer is the most common solid-organ malignancy among American men. It is currently most commonly diagnosed on random systematic biopsies prompted by elevated serum PSA levels. Multi-parametric MRI (MP-MRI) of the prostate has emerged as an anatomic and functional imaging modality, which offers accurate detection, localization and staging of prostate cancer. Recently, MP-MRI has gained an increasing role in guiding biopsies to sites of abnormality and in monitoring patients on active surveillance. Here, we discuss the historical development, current role, and potential future directions of MP-MRI in the diagnosis of prostate cancer.
authors.affiliation: Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, 10 Center Drive, Building 10 - CRC, Bethesda, MD, 20892, USA.
authors.forename: Soroush
authors.initials: S
authors.lastname: Rais-Bahrami
authors.forename: Baris
authors.initials: B
authors.lastname: Turkbey
authors.forename: Kinzya B
authors.initials: KB
authors.lastname: Grant
authors.forename: Peter A
authors.initials: PA
authors.lastname: Pinto
authors.forename: Peter L
authors.initials: PL
authors.lastname: Choyke
mesh_terms: D003287:Contrast Media; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008297:Male; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology
chemical_list: D003287:Contrast Media