title: Endobronchial valves for advanced emphysema: an endobronchial follow-up.
abstract: Lung volume reduction surgery is a therapeutic option for selected patients with advanced emphysema. However, it is an invasive procedure benefitting only a selected group of patients with heterogeneous upper lobe predominant disease and limited exercise capacity. The most widely studied alternatives are endobronchial valves. Hundreds of patients worldwide have undergone endobronchial valve placement. Although short-term outcomes have been described, little is known about the long-term side effects following this treatment, and endoscopic follow-up is virtually nonexistent. The images, biopsies, and microbiologic evidence accrued from this patient are witnesses to the natural evolution of endobronchial valves in the airways and should offer a word of caution with regard to valve placement in patients with life expectancies exceeding those typical of severe chronic obstructive lung disease.
authors.affiliation: *Pulmonary Department, Clínica Universidad de Navarra, Pamplona †Pulmonary Department, IIS-Fundación Jimenez Díaz-CIBERES, Madrid, Spain.
authors.forename: Pablo S
authors.initials: PS
authors.lastname: Salcedo
authors.forename: Luis M
authors.initials: LM
authors.lastname: Seijo
authors.forename: Javier J
authors.initials: JJ
authors.lastname: Zulueta
mesh_terms: D000368:Aged; D001980:Bronchi / Q000601:surgery*; D001999:Bronchoscopy; D016971:Citrobacter freundii / Q000302:isolation & purification; D003352:Corynebacterium / Q000302:isolation & purification; D003354:Corynebacterium Infections / Q000150:complications / Q000188:drug therapy; D020878:Device Removal; D019160:Endosonography; D004756:Enterobacteriaceae Infections / Q000150:complications / Q000188:drug therapy; D005500:Follow-Up Studies; D016905:Gram-Negative Bacterial Infections / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007710:Klebsiella Infections / Q000150:complications / Q000188:drug therapy; D007711:Klebsiella pneumoniae / Q000302:isolation & purification; D008297:Male; D020613:Morganella morganii / Q000302:isolation & purification; D019736:Prostheses and Implants / Q000382:microbiology; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D011656:Pulmonary Emphysema / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D020615:Stenotrophomonas maltophilia / Q000302:isolation & purification; D016896:Treatment Outcome