title: Approaches to the treatment of disease induced by chikungunya virus.
abstract: Chikungunya virus, a re-emerging mosquito-borne alphavirus, causes fever, rash and persistent arthralgia/arthritis in humans. Severe outbreaks have occurred resulting in infections of millions of people in Southeast Asia and Africa. Currently there are no antiviral drugs or vaccines for prevention and treatment of chikungunya infections. Herein we report the current status of research on antiviral drugs and vaccines for chikungunya virus infections.
authors.forename: Jayaram
authors.initials: J
authors.lastname: Bettadapura
authors.forename: Lara J
authors.initials: LJ
authors.lastname: Herrero
authors.forename: Adam
authors.initials: A
authors.lastname: Taylor
authors.affiliation: Emerging Viruses & Inflammation Research Group, Institute for Glycomics, Griffith University, Queensland, Australia.
authors.forename: Suresh
authors.initials: S
authors.lastname: Mahalingam
mesh_terms: D000330:Aedes / Q000821:virology; D000349:Africa / Q000453:epidemiology; D018354:Alphavirus Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000276:immunology / Q000635:transmission; D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use*; D001210:Asia, Southeastern; D065632:Chikungunya Fever; D002646:Chikungunya virus / Q000276:immunology* / Q000472:pathogenicity; D004196:Disease Outbreaks; D005334:Fever / Q000188:drug therapy / Q000453:epidemiology / Q000821:virology; D006801:Humans; D007303:Insect Vectors; D014612:Vaccines / Q000627:therapeutic use*
chemical_list: D000998:Antiviral Agents; D014612:Vaccines