title: Combined electrochemical/chemical methods for the synthesis and the molecular diversifying of isoindolinone-based heterocyclic scaffolds.
abstract: By means of C-H acids activation on Pt-cathode, an electrochemically initiated strategy aimed to developing a diversity-oriented synthesis based on the isoindolinone nucleus has been established. Conveniently, the achievement of a small library of new heterocycle-fused isoindolinone compounds with potential interest for drug design was carried out by using tandem reactions and one-pot sequential processes.
authors.affiliation: Dipartimento di Chimica e Biologia, Università di Salerno, Via Giovanni Paolo II, 132-84084 , Fisciano, SA, Italy, lpalombi@unisa.it.
authors.forename: Laura
authors.initials: L
authors.lastname: Palombi
authors.forename: Antonia
authors.initials: A
authors.lastname: Di Mola
authors.forename: Chiara
authors.initials: C
authors.lastname: Vignes
authors.forename: Antonio
authors.initials: A
authors.lastname: Massa
mesh_terms: D060326:Chemistry Techniques, Synthetic; D004563:Electrochemistry; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D006571:Heterocyclic Compounds; D007211:Indoles