title: Pathogen virulence of Phytophthora infestans: from gene to functional genomics.
abstract: The oomycete, Phytophthora infestans, is one of the most important plant pathogens worldwide. Much of the pathogenic success of P. infestans, the potato late blight agent, relies on its ability to generate large amounts of sporangia from mycelia, which release zoospores that encyst and form infection structures. Until recently, little was known about the molecular basis of oomycete pathogenicity by the avirulence molecules that are perceived by host defenses. To understand the molecular mechanisms interplay in the pathogen and host interactions, knowledge of the genome structure was most important, which is available now after genome sequencing. The mechanism of biotrophic interaction between potato and P. infestans could be determined by understanding the effector biology of the pathogen, which is until now poorly understood. The recent availability of oomycete genome will help in understanding of the signal transduction pathways followed by apoplastic and cytoplasmic effectors for translocation into host cell. Finally based on genomics, novel strategies could be developed for effective management of the crop losses due to the late blight disease.
authors.affiliation: Central potato Research Institute, Shimla, H.P India 171001.
authors.forename: Suman
authors.initials: S
authors.lastname: Sanju
authors.affiliation: Central potato Research Institute, Shimla, H.P India 171001.
authors.forename: Aditi
authors.initials: A
authors.lastname: Thakur
authors.affiliation: Central potato Research Institute, Shimla, H.P India 171001.
authors.forename: Sundresha
authors.initials: S
authors.lastname: Siddappa
authors.affiliation: National Research Centre for Plant Biotechnology, IARI campus, Pusa, New Delhi-12, India.
authors.forename: Rohini
authors.initials: R
authors.lastname: Sreevathsa
authors.affiliation: Department of Biosciences and Biotechnology, Banasthali University (Rajasthan), Tonk, India 304022.
authors.forename: Nidhi
authors.initials: N
authors.lastname: Srivastava
authors.affiliation: Department of Biological Sciences, School of Basic Sciences, SHIATS, Naini, Allahabad, India 211007.
authors.forename: Pradeep
authors.initials: P
authors.lastname: Shukla
authors.affiliation: Central potato Research Institute, Shimla, H.P India 171001.
authors.forename: B P
authors.initials: BP
authors.lastname: Singh
keywords: Crinklers; Effectors; GPCR; Oomycetes; Phytophthora infestans; RXLR –dEER; Signal molecule