title: A randomized, controlled trial of Social Cognition and Interaction Training (SCIT) for outpatients with schizophrenia spectrum disorders.
abstract: OBJECTIVE
  In schizophrenia, the ability to adaptively infer the thoughts and feelings of others (i.e., social cognition) is strongly associated with community functioning. Researchers have designed psychosocial interventions to improve social cognition with the aim of improving downstream social functioning. Social Cognition and Interaction Training (SCIT) is one such intervention. Previous research on SCIT has been promising, but has consisted largely of smaller trials with insufficient experimental control.
  
  
  METHODS
  Randomized, controlled trial.
  
  
  METHODS
  The current article reports on a controlled trial of 66 adults with schizophrenia randomized to receive either SCIT (n = 33), delivered in weekly group sessions, or treatment as usual (n = 33) for 6 months. Participants completed assessments of social cognition, social functioning, neurocognition and symptoms at baseline, post-treatment, and 3-month follow-up.
  
  
  RESULTS
  Primary analyses suggest that SCIT may improve social functioning, negative symptoms, and possibly hostile attributional bias. Post-hoc analyses suggest a dose-response effect.
  
  
  CONCLUSIONS
  Findings are discussed in the context of continuing to refine and improve social cognitive interventions for schizophrenia.
  
  
  CONCLUSIONS
  Social cognitive intervention is a feasible and promising approach to improving social functioning among individuals with schizophrenia-spectrum disorders. Dose-response findings suggest that delivering social cognitive interventions with greater frequency may maximize their benefit to patients. Research on social cognitive interventions is still young and effects from well-controlled trials have been inconsistent. It is not yet clear which components of social cognitive training may be the key active ingredients.
authors.affiliation: University of Texas Health Science Center, San Antonio, USA.
authors.forename: David L
authors.initials: DL
authors.lastname: Roberts
authors.forename: Dennis R
authors.initials: DR
authors.lastname: Combs
authors.forename: Michael
authors.initials: M
authors.lastname: Willoughby
authors.forename: Jim
authors.initials: J
authors.lastname: Mintz
authors.forename: Clare
authors.initials: C
authors.lastname: Gibson
authors.forename: Betty
authors.initials: B
authors.lastname: Rupp
authors.forename: David L
authors.initials: DL
authors.lastname: Penn
mesh_terms: D000328:Adult; D003071:Cognition / Q000502:physiology; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D008875:Middle Aged; D010045:Outpatients / Q000523:psychology* / Q000706:statistics & numerical data; D011615:Psychotherapy, Group; D012559:Schizophrenia / Q000628:therapy*; D012917:Social Adjustment; D016896:Treatment Outcome
keywords: Schizophrenia; attributional bias; emotion perception; remediation; social cognition; social functioning; theory of mind; training; treatment