title: Development and investigation of a mesh-electrode linear ion trap (ME-LIT) mass analyzer.
abstract: A mesh-electrode linear ion trap (ME-LIT) mass analyzer was developed and its performance was primarily characterized. In conventional linear ion trap mass analyzers, the trapped ions are mass-selected and then ejected in a radial direction by a slot on a trap electrode. The presence of slots can strongly affect the electric field distribution in the ion trapping region and distort the mass analysis performance. To compensate for detrimental electric field effects, the slot is usually designed and fabricated to be as small as possible, and also has very high mechanical accuracy and symmetry. A ME-LIT with several mesh electrodes was built to compensate for the effects caused by slots. Each mesh electrode was fabricated from a plate electrode with a relatively large slot and the slot was covered with a conductive mesh. Our preliminary experimental results show that the ME-LIT could considerably diminish the detrimental electric field effects caused by slots, and increase the mass resolving power and ion detection efficiency. Even with 4-mm-wide slots, a mass resolution in excess of 600 was obtained using the ME-LIT. Mass resolution could be remarkably improved using mesh electrodes in ion traps with asymmetric electrodes. The stability diagram of the ME-LIT was mapped, and highly efficient tandem mass spectrometry was demonstrated. The ME-LIT was qualified as a LIT mass analyzer. The ME-LIT can improve the mass resolution and decrease the requirements of mechanical accuracy and symmetry of slots, so it shows potential for a wide range of practical uses.
authors.affiliation: Department of Chemistry and Laser Chemistry Institute, Fudan University, Shanghai, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Wang
authors.forename: Fuxing
authors.initials: F
authors.lastname: Xu
authors.forename: Xinhua
authors.initials: X
authors.lastname: Dai
authors.forename: Xiang
authors.initials: X
authors.lastname: Fang
authors.forename: Chuan-Fan
authors.initials: CF
authors.lastname: Ding
mesh_terms: D003198:Computer Simulation; D004566:Electrodes; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods; D008956:Models, Chemical; D009842:Oligopeptides / Q000032:analysis / Q000737:chemistry; D053719:Tandem Mass Spectrometry / Q000295:instrumentation / Q000379:methods
chemical_list: D009842:Oligopeptides