title: Antibiotic resistance and detection of the sul2 gene in urinary isolates of Escherichia coli in patients from Brazil.
abstract: BACKGROUND
  The present study aimed to assess the antibiotic resistance profiles and detect the presence of the sul2 gene in sulfamethoxazole-susceptible and resistant isolates of Escherichia coli obtained from outpatients and inpatients with urinary tract infections.
  
  
  METHODS
  The resistance profiles of 739 strains were assessed and the presence of the sul2 gene in 100 isolates was tested.
  
  
  RESULTS
  The antibiotics with the highest resistance rates were ampicillin (57.4%) and trimethoprim-sulfamethoxazole (44.7%). The presence of the gene sul2 was detected in 66.7% of outpatient samples and 67.9% of inpatient samples.
  
  
  CONCLUSIONS
  Our results demonstrate that E. coli isolates exhibit high resistance to various classes of antibiotics, highlighting the need for developing strategies to help in prescribing antibiotics.
authors.affiliation: Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. alinet@cbiot.ufrgs.br.
authors.forename: Aline
authors.initials: A
authors.lastname: Teichmann
authors.forename: Homero Neto de Cunha
authors.initials: HN
authors.lastname: Agra
authors.forename: Luciana de Souza
authors.initials: Lde S
authors.lastname: Nunes
authors.forename: Marion Pereira
authors.initials: MP
authors.lastname: da Rocha
authors.forename: Jane Dagmar Pollo
authors.initials: JD
authors.lastname: Renner
authors.forename: Lia Gonçalves
authors.initials: LG
authors.lastname: Possuelo
authors.forename: Marcelo
authors.initials: M
authors.lastname: Carneiro
authors.forename: Alexandre
authors.initials: A
authors.lastname: Rieger
authors.forename: Lisianne Brittes
authors.initials: LB
authors.lastname: Benitez
authors.forename: Andréia Rosane de Moura
authors.initials: AR
authors.lastname: Valim
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics*; D001938:Brazil; D002352:Carrier Proteins / Q000235:genetics*; D003430:Cross-Sectional Studies; D024881:Drug Resistance, Bacterial; D004352:Drug Resistance, Microbial; D004927:Escherichia coli Infections / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D014552:Urinary Tract Infections / Q000382:microbiology*; D056689:Uropathogenic Escherichia coli / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D002352:Carrier Proteins; C491369:Sul2 protein, bacteria