title: The Correlative Study of Serum Pseudo-cholinesterase, Biological Parameters and Symptoms Among Occupational Workers.
abstract: Cholinesterase is one of many important enzymes needed for acetylcholine hydrolysis. This study aimed to evaluate the serum pseudo-cholinesterase (BuChE) level and its relation to biological parameters (hematological and biochemical parameters) and symptoms among occupational workers, gasoline station worker in Bangkok, Thailand. Our results revealed that the average BuChE level was in normal range, but it had strong relation to hemoglobin (Hb), hematocrit (Hct), blood urea nitrogen (BUN), creatinine (Cr) and serum glutamic pyruvic trans-aminase (SGPT) (Linear regression analysis, p < 0.05, p < 0.05, p < 0.01, p = 0.001 and p < 0.01 respectively). Although, BuChE was not related to white blood cell parameters, but it may exhibit the skin irritation (p = 0.058) of the workers as it showed significant correlation to conjunctivitis and nausea (Pearson's correlation, p < 0.01 and p < 0.05). In conclusion, this finding may explain that BuChE was significantly related to red blood cells (RBC), liver and kidney functions.
authors.affiliation: College of Public Health Sciences, Chulalongkorn University, Institute Building 2-3, Soi Chulalongkorn 62 Phyathai Rd., Bangkok, 10330 Thailand.
authors.forename: Tanasorn
authors.initials: T
authors.lastname: Tunsaringkarn
authors.affiliation: College of Public Health Sciences, Chulalongkorn University, Institute Building 2-3, Soi Chulalongkorn 62 Phyathai Rd., Bangkok, 10330 Thailand.
authors.forename: Kalaya
authors.initials: K
authors.lastname: Zapuang
authors.affiliation: College of Public Health Sciences, Chulalongkorn University, Institute Building 2-3, Soi Chulalongkorn 62 Phyathai Rd., Bangkok, 10330 Thailand.
authors.forename: Anusorn
authors.initials: A
authors.lastname: Rungsiyothin
keywords: Biological parameters; Gasoline station workers; Serum cholinesterase; Symptoms