title: Unlocking new therapeutic targets and resistance mechanisms in mantle cell lymphoma.
abstract: Mantle cell lymphoma is an aggressive tumor for which new drugs targeting underlying molecular mechanisms are opening promising avenues. A recent study has elucidated the basis for targeting B cell receptor signaling in these lymphomas and identified somatic mutations in NF-κB regulatory genes that confer resistance to this therapy.
authors.affiliation: Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona 08036, Spain.
authors.forename: Dolors
authors.initials: D
authors.lastname: Colomer
authors.affiliation: Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona 08036, Spain. Electronic address: ecampo@clinic.ub.es.
authors.forename: Elías
authors.initials: E
authors.lastname: Campo