title: The Cache County Study on Memory in Aging: factors affecting risk of Alzheimer's disease and its progression after onset.
abstract: The Cache County Study on Memory in Aging is a longitudinal, population-based study of Alzheimer's disease (AD) and other dementias. Initiated in 1995 and extending to 2013, the study has followed over 5,000 elderly residents of Cache County, Utah (USA) for over twelve years. Achieving a 90% participation rate at enrolment, and spawning two ancillary projects, the study has contributed to the literature on genetic, psychosocial and environmental risk factors for AD, late-life cognitive decline, and the clinical progression of dementia after its onset. This paper describes the major study contributions to the literature on AD and dementia.
authors.affiliation: Department of Psychology, Utah State University , Logan, UT.
authors.forename: Joann T
authors.initials: JT
authors.lastname: Tschanz
authors.forename: Maria C
authors.initials: MC
authors.lastname: Norton
authors.forename: Peter P
authors.initials: PP
authors.lastname: Zandi
authors.forename: Constantine G
authors.initials: CG
authors.lastname: Lyketsos
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D000544:Alzheimer Disease / Q000188:drug therapy / Q000453:epidemiology* / Q000235:genetics; D003072:Cognition Disorders / Q000188:drug therapy / Q000453:epidemiology* / Q000235:genetics; D018450:Disease Progression; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008568:Memory / Q000502:physiology; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D013315:Stress, Psychological / Q000150:complications / Q000453:epidemiology; D014589:Utah / Q000453:epidemiology