title: Isolation, characterization and sensory evaluation of a Hexa beta-D-glucopyranosyl diterpene from Stevia rebaudiana.
abstract: From the extract of the leaves of Stevia rebaudiana Bertoni, a diterpene glycoside was isolated which was identified as 13-[(2-O-beta-D-glucopyranosyl-3-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy] ent-kaur-16-en-19-oic acid-(2-O-beta-D-glucopyranosyl-3-O-beta-D-glucopyranosyl-D-glucopyranosyl) ester (1). The complete 1H and 13C NMR assignment of 1 is reported for the first time, from extensive NMR (1H and 13C, COSY, HSQC, and HMBC) and mass spectral data. Also, we report the sensory evaluation of 1 against sucrose for the sweetness property of this molecule.
authors.affiliation: The Coca-Cola Company, Organic Chemistry Department, Global Research and Development, One Coca-Cola Plaza, Atlanta, GA 30313, USA. iprakash@coca-cola.com
authors.forename: Indra
authors.initials: I
authors.lastname: Prakash
authors.affiliation: The Coca-Cola Company, Organic Chemistry Department, Global Research and Development, One Coca-Cola Plaza, Atlanta, GA 30313, USA.
authors.forename: Venkata Sai Prakash
authors.initials: VS
authors.lastname: Chaturvedula
authors.affiliation: PureCircle SDN BHD, Lengkuk Teknologi, 71760 Bandar ENSTEK, Negeri Sembilan, Malaysia.
authors.forename: Avetik
authors.initials: A
authors.lastname: Markosyan
mesh_terms: D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D036625:Stevia / Q000737:chemistry*; D013395:Sucrose; D013649:Taste
chemical_list: D004224:Diterpenes; D013395:Sucrose