title: Transfacial versus endoscopic approach in the treatment of woodworker's nasal adenocarcinomas.
abstract: BACKGROUND
  The purpose of this study was to present a monocentric retrospective study designed to compare oncologic results and morbidity between transfacial surgery and endoscopic endonasal surgery for nasal adenocarcinomas.
  
  
  METHODS
  Between 1998 and 2003, 31 patients were operated on via transfacial surgery, and between 2004 and 2009, 43 patients were operated on via endoscopic endonasal surgery. Overall and specific survival, local control, and morbidity (length of hospitalization, intensive care unit [ICU] monitoring, need for nasal packing, and complications) were compared.
  
  
  RESULTS
  There was no difference in prognostic factors between groups, but the median age was significantly higher for endoscopic endonasal surgery. Three-year overall survival, specific survival, and local control were not different between groups (respectively, 76.7%, 86%, and 81.4% for endoscopic endonasal surgery vs 61.3%, 67.7%, and 71% for transfacial surgery). Morbidity was significantly lower with endoscopic endonasal surgery for all criteria.
  
  
  CONCLUSIONS
  Endoscopic surgery may replace transfacial surgery in the treatment of woodworker's adenocarcinomas. Older patients can be operated on by decreasing morbidity and mortality with at least similar oncologic results.
authors.affiliation: Head and Neck Surgery, CHU, de Nancy-Hôpital Central, Nancy, France; University of Lorraine, Nancy, France.
authors.forename: Rémy
authors.initials: R
authors.lastname: Grosjean
authors.forename: Patrice
authors.initials: P
authors.lastname: Gallet
authors.forename: Cédric
authors.initials: C
authors.lastname: Baumann
authors.forename: Roger
authors.initials: R
authors.lastname: Jankowski
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D000368:Aged; D000704:Analysis of Variance; D002423:Cause of Death; D015331:Cohort Studies; D016001:Confidence Intervals; D018572:Disease-Free Survival; D004391:Dust; D004724:Endoscopy / Q000379:methods* / Q000401:mortality; D005145:Face / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D059747:Nasal Surgical Procedures / Q000379:methods*; D009361:Neoplasm Invasiveness / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology; D009367:Neoplasm Staging; D009669:Nose Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D009784:Occupational Diseases / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D018570:Risk Assessment; D016019:Survival Analysis; D016896:Treatment Outcome; D014934:Wood
chemical_list: D004391:Dust
keywords: MesH database; cribriform plate; endonasal endoscopic surgery; ethmoid; paranasal sinus cancer; skull base neoplasms