title: Ultrafast synaptic endocytosis cycles to the center stage.
abstract: Upon synaptic vesicle fusion, the neuronal membrane surface expands. Clathrin-mediated endocytosis compensates for this expansion but is a slow process. Recent studies in eLife and Nature identify an ultrafast mode of endocytosis, occurring in the space between active and periactive zones, that compensates for membrane addition during vesicle fusion.
authors.affiliation: VIB Center for the Biology of Disease, 3000 Leuven, Belgium; Department of Human Genetics, KU Leuven, 3000 Leuven, Belgium.
authors.forename: Lujia
authors.initials: L
authors.lastname: Zhou
authors.affiliation: VIB Center for the Biology of Disease, 3000 Leuven, Belgium; Department of Human Genetics, KU Leuven, 3000 Leuven, Belgium.
authors.forename: Joseph
authors.initials: J
authors.lastname: McInnes
authors.affiliation: VIB Center for the Biology of Disease, 3000 Leuven, Belgium; Department of Human Genetics, KU Leuven, 3000 Leuven, Belgium. Electronic address: patrik.verstreken@cme.vib-kuleuven.be.
authors.forename: Patrik
authors.initials: P
authors.lastname: Verstreken
mesh_terms: D000818:Animals; D004705:Endocytosis; D006624:Hippocampus / Q000166:cytology*; D013569:Synapses / Q000378:metabolism*