title: Cutaneous protothecosis in a patient with hypogammaglobulinemia.
abstract: Prototheca wickerhamii has been predominantly recognised as a pathogen in immunocompromised hosts with deficits in innate or cellular immunity. The role of specific immunoglobulin against Prototheca in host immunity is uncertain. We describe a case of persistent cutaneous protothecosis in a patient with hypogammaglobulinemia most likely due to common variable immunodeficiency, with clinical response to voriconazole.
authors.affiliation: Austin Centre for Infection Research, Austin Health, Heidelberg, VIC 3084, Australia ; Department of Microbiology, Austin Health, Heidelberg, VIC 3084, Australia.
authors.forename: Jason C
authors.initials: JC
authors.lastname: Kwong
authors.affiliation: Department of Microbiology, Austin Health, Heidelberg, VIC 3084, Australia.
authors.forename: Peter B
authors.initials: PB
authors.lastname: Ward
authors.affiliation: Austin Centre for Infection Research, Austin Health, Heidelberg, VIC 3084, Australia.
authors.forename: Paul D
authors.initials: PD
authors.lastname: Johnson
keywords: Common variable immunodeficiency; Hypogammaglobulinemia; Prototheca; Protothecosis; Voriconazole