title: Accelerated whole-heart coronary MRA using motion-corrected sensitivity encoding with three-dimensional projection reconstruction.
abstract: OBJECTIVE
  To achieve whole-heart coronary magnetic resonance angiography (MRA) with (1.0 mm)(3) spatial resolution and 5 min of free-breathing scan time.
  
  
  METHODS
  We used an electrocardiograph-gated, T2-prepared and fat-saturated balanced steady state free precession sequence with 3DPR trajectory for free-breathing data acquisition with 100% gating efficiency. For image reconstruction, we used a self-calibrating iterative SENSE scheme with integrated retrospective motion correction. We performed healthy volunteer study to compare the proposed method with motion-corrected gridding at different retrospective undersampling levels on apparent signal-to-noise ratio (aSNR) and subjective coronary artery (CA) visualization scores.
  
  
  RESULTS
  Compared with gridding, the proposed method significantly improved both image quality metrics for undersampled datasets with 6000, 8000, and 10,000 projections. With as few as 10,000 projections, the proposed method yielded good CA visualization scores (3.02 of 4) and aSNR values comparable to those with 20,000 projections.
  
  
  CONCLUSIONS
  Using the proposed method, good image quality was observed for free breathing whole-heart coronary MRA at (1.0 mm)(3) resolution with an achievable scan time of 5 min.
authors.affiliation: Department of Radiology and Biomedical Engineering, Northwestern University, Chicago, Illinois, USA.|Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
authors.forename: Jianing
authors.initials: J
authors.lastname: Pang
authors.affiliation: Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
authors.forename: Behzad
authors.initials: B
authors.lastname: Sharif
authors.affiliation: Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
authors.forename: Reza
authors.initials: R
authors.lastname: Arsanjani
authors.affiliation: MR R&D, Siemens Healthcare, Los Angeles, California, USA.
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Bi
authors.affiliation: Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
authors.forename: Zhaoyang
authors.initials: Z
authors.lastname: Fan
authors.affiliation: Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Yang
authors.affiliation: Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Kuncheng
authors.initials: K
authors.lastname: Li
authors.affiliation: Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Berman
authors.affiliation: Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.|University of California, Los Angeles, California, USA.
authors.forename: Debiao
authors.initials: D
authors.lastname: Li
mesh_terms: D000465:Algorithms; D016477:Artifacts; D055424:Cardiac-Gated Imaging Techniques / Q000379:methods*; D017023:Coronary Angiography / Q000379:methods; D003331:Coronary Vessels / Q000033:anatomy & histology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D009038:Motion; D009068:Movement; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
keywords: 3D radial acquisition; coronary MRA; motion correction; sensitivity encoding