title: Zinc-catalyzed borylation of primary, secondary and tertiary alkyl halides with alkoxy diboron reagents at room temperature.
abstract: A new catalytic system based on a Zn(II) NHC precursor has been developed for the cross-coupling reaction of alkyl halides with diboron reagents, which represents a novel use of a Group XII catalyst for CX borylation. This approach gives borylations of unactivated primary, secondary, and tertiary alkyl halides at room temperature to furnish alkyl boronates, with good functional-group compatibility, under mild conditions. Preliminary mechanistic investigations demonstrated that this borylation reaction seems to involve one-electron processes.
authors.affiliation: Institut für Anorganische Chemie, Julius-Maximilians-Universität Würzburg, Am Hubland, 97074 Würzburg (Germany).
authors.forename: Shubhankar Kumar
authors.initials: SK
authors.lastname: Bose
authors.forename: Katharina
authors.initials: K
authors.lastname: Fucke
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.forename: Patrick G
authors.initials: PG
authors.lastname: Steel
authors.forename: Todd B
authors.initials: TB
authors.lastname: Marder
keywords: N-heterocyclic carbenes; Suzuki-Miyaura; boronate esters; cross-coupling; homogeneous catalysis