title: The prevalence of gastroduodenal mucosal injuries in aspirin users.
abstract: BACKGROUND
  Aspirin is a widely used medication for primary and secondary prevention of cardiovascular and cerebrovascular events. The gastrointestinal risks of aspirin are well known, but the frequency of gastroduodenal mucosal injuries in aspirin users in Thailand is currently unknown.
  
  
  OBJECTIVE
  The present study was performed to investigate the prevalence of gastroduodenal mucosal injuries in asymptomatic aspirin users.
  
  
  METHODS
  Asymptomatic patients taking low doses ofaspirin without gastroprotective medication were enrolled and underwent esophagogastroduodenoscopy
  
  
  RESULTS
  One hundred four patients were endoscoped. The prevalence of gastroduodenal mucosal injuries (erosions or ulcer) was 63.5%.
  
  
  CONCLUSIONS
  The prevalence of gastroduodenal mucosal injuries was very high in asymptomatic aspirin users.
authors.affiliation: Department of Medicine, Bangkok Metropolitan Administration General Hospital, Bangkok, Thailand. tthirada@yahoo.com
authors.forename: Thirada
authors.initials: T
authors.lastname: Thongbai
mesh_terms: D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects*; D058070:Asymptomatic Diseases; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects* / Q000473:pathology*; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects* / Q000473:pathology*; D008297:Male; D008875:Middle Aged
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin