title: Thyroid disorders in patients of type 2 diabetes mellitus.
abstract: The study was planned to assess the prevalence of thyroid disorders in type 2 diabetes in North Indian population and to correlate the serum insulin and glycosylated haemoglobin levels with thyroid hormones. It is a case control study. One hundred and twenty patients of type 2 diabetes were included in the study along with 117 adults of the same age group and normal glucose levels as controls. All blood samples were taken from subjects who fasted for at least 12 h before the blood collection. Glycosylated hemoglobin was determined by ion exchange chromatography and serum insulin and thyroid hormones were assessed through enzyme linked immunosorbent assay. Fasting blood glucose and glycosylated haemoglobin levels were significantly higher in diabetics showing a poor glucose control. Serum tri-iodothyronine values were significantly lower in diabetics. There was a significant correlation between glycosylated haemoglobin and thyroid hormones. There was no correlation between serum insulin and thyroid hormones.
authors.affiliation: Environmental Biochemistry and Molecular Biology Laboratory, Department of Biochemistry, University College of Medical Sciences & Guru Teg Bhadur Hospital, New Delhi, India.
authors.forename: Vibha
authors.initials: V
authors.lastname: Uppal
authors.affiliation: Department of Biochemistry, Government Medical College, Patiala, India.
authors.forename: Chittranjan
authors.initials: C
authors.lastname: Vij
authors.affiliation: Department of Biochemistry, Government Medical College, Patiala, India.
authors.forename: Gurdeep Kaur
authors.initials: GK
authors.lastname: Bedi
authors.affiliation: Department of Medicine, Government Medical College, Patiala, India.
authors.forename: Anil
authors.initials: A
authors.lastname: Vij
authors.affiliation: Environmental Biochemistry and Molecular Biology Laboratory, Department of Biochemistry, University College of Medical Sciences & Guru Teg Bhadur Hospital, New Delhi, India.
authors.forename: Basu Dev
authors.initials: BD
authors.lastname: Banerjee
keywords: Endocrine disorders; Glycemic control; Glycosylated haemoglobin; Hyperthyroidism; Hypothyroidism; Insulin; Thyroid hormones