title: Ho(a)xing autophagy to regulate development.
abstract: In this issue of Developmental Cell, Banreti et al. (2014) demonstrate that canonical autophagy is inhibited in the Drosophila fat body by Hox transcriptional factors. This regulation involves repression of the Atg genes. Programmed developmental autophagy is thus under Hox control and may influence cell fate determination.
authors.affiliation: IRCCS Fondazione Santa Lucia, 00143 Rome, Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Campello
authors.affiliation: IRCCS Fondazione Santa Lucia, 00143 Rome, Italy; Unit of Cell Stress and Survival, Danish Cancer Society Research Center, 2100 Copenhagen, Denmark; Department of Biology, University of Rome Tor Vergata, 00133 Rome, Italy. Electronic address: cecconi@cancer.dk.
authors.forename: Francesco
authors.initials: F
authors.lastname: Cecconi
mesh_terms: D000818:Animals; D001343:Autophagy; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000378:metabolism*
chemical_list: D018398:Homeodomain Proteins