title: Use of the pressure wire method for measuring pulmonary arterial pressures in patients with pulmonary atresia.
abstract: OBJECTIVE
  The objective of the study was to analyse the use of the pressure wire for the acquisition of intravascular pulmonary pressures in the presence of pulmonary atresia and systemic-dependent pulmonary blood flow.
  
  
  METHODS
  In this study, we included patients with pulmonary atresia and systemic-dependent pulmonary circulation referred for diagnostic catheterisation for evaluation of pulmonary pressures during the period from April, 2012 to April, 2013. The systemic-pulmonary collateral arteries were selectively catheterised, and in the absence of a critical stenosis angiographically determined; the pressure wire was introduced in these arteries to reach the main pulmonary artery, and/or lobar, and segmental branches. Aortic and pulmonary pressures were simultaneously obtained. We evaluated the feasibility and safety of the method.
  
  
  RESULTS
  We studied 10 patients (age 21 days to 11 years). In all of them, the pressures of pulmonary circulation - main artery, and/or lobar, and segmental branches - were successfully measured with the pressure wire. Of eight patients with indication for Rastelli surgery, the pulmonary pressures were considered normal in five, and slightly increased in three. In two patients requiring univentricular correction - total cavopulmonary anastomosis - the diastolic pressure was increased (20 mmHg). All procedures were performed without haemodynamic instability, cardiac arrhythmia, systemic saturation reduction, death, or any other complication.
  
  
  CONCLUSIONS
  Measurement of pulmonary vascular pressures using the pressure wire in small patients with pulmonary atresia is safe and effective. It allows the acquisition of reliable pressure curves, even in the presence of small vessels, bending and tortuosity, without the risk usually associated with the use of conventional diagnostic catheters.
authors.affiliation: Division of Cardiology,Department of Internal Medicine,Hospital das Clínicas - Ribeirão Preto Medical School,University of São Paulo,Brazil.
authors.forename: Jorge L
authors.initials: JL
authors.lastname: Haddad
authors.affiliation: Division of Cardiology,Department of Internal Medicine,Hospital das Clínicas - Ribeirão Preto Medical School,University of São Paulo,Brazil.
authors.forename: Gustavo C
authors.initials: GC
authors.lastname: Novaes
authors.affiliation: Division of Cardiology,Department of Internal Medicine,Hospital das Clínicas - Ribeirão Preto Medical School,University of São Paulo,Brazil.
authors.forename: Geraldo L
authors.initials: GL
authors.lastname: Figueiredo
authors.affiliation: Division of Cardiology,Department of Internal Medicine,Hospital das Clínicas - Ribeirão Preto Medical School,University of São Paulo,Brazil.
authors.forename: Daniel C
authors.initials: DC
authors.lastname: Lemos
authors.affiliation: Division of Cardiology,Department of Internal Medicine,Hospital das Clínicas - Ribeirão Preto Medical School,University of São Paulo,Brazil.
authors.forename: Leon G R
authors.initials: LG
authors.lastname: Macedo
authors.affiliation: Division of Cardiology,Department of Internal Medicine,Hospital das Clínicas - Ribeirão Preto Medical School,University of São Paulo,Brazil.
authors.forename: Igor M
authors.initials: IM
authors.lastname: Lago
authors.affiliation: Division of Cardiology,Department of Internal Medicine,Hospital das Clínicas - Ribeirão Preto Medical School,University of São Paulo,Brazil.
authors.forename: Rafael B
authors.initials: RB
authors.lastname: Pavão
authors.affiliation: Division of Cardiology,Department of Internal Medicine,Hospital das Clínicas - Ribeirão Preto Medical School,University of São Paulo,Brazil.
authors.forename: André V
authors.initials: AV
authors.lastname: Badran
authors.affiliation: Division of Cardiology,Department of Internal Medicine,Hospital das Clínicas - Ribeirão Preto Medical School,University of São Paulo,Brazil.
authors.forename: Moysés O
authors.initials: MO
authors.lastname: Lima-Filho
authors.affiliation: Division of Cardiology,Department of Internal Medicine,Hospital das Clínicas - Ribeirão Preto Medical School,University of São Paulo,Brazil.
authors.forename: Paulo H
authors.initials: PH
authors.lastname: Manso
authors.affiliation: Division of Cardiology,Department of Internal Medicine,Hospital das Clínicas - Ribeirão Preto Medical School,University of São Paulo,Brazil.
authors.forename: José A
authors.initials: JA
authors.lastname: Marin-Neto
mesh_terms: D006328:Cardiac Catheterization / Q000295:instrumentation*; D002648:Child; D002675:Child, Preschool; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011312:Pressure; D011446:Prospective Studies; D011651:Pulmonary Artery / Q000503:physiopathology*; D018633:Pulmonary Atresia / Q000175:diagnosis / Q000503:physiopathology*; D011669:Pulmonary Wedge Pressure / Q000502:physiology*; D015203:Reproducibility of Results