title: Kyrle's disease.
abstract: Kyrle's disease (KD) is a dermatosis which was first described by Kyrle as "hyperkeratosis follicularis et parafollicularis in cutem penetrans" in 1916. Perforating dermatoses are a heterogeneous disorder group characterised by transepithelial elimination. KD has been seen in association with multiple disorders, including diabetes mellitus, renal and liver diseases, congestive heart failure, hyperlipidaemia, infective diseases and abnormal metabolism of vitamin A. This case report presents two patients with KD with associated systemic disease.
authors.affiliation: Konya Training and Research Hospital, Konya, Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Ataseven
authors.forename: Perihan
authors.initials: P
authors.lastname: Ozturk
authors.forename: Iknur
authors.initials: I
authors.lastname: Kucukosmanoglu
authors.forename: Gulcan Saylam
authors.initials: GS
authors.lastname: Kurtipek
mesh_terms: D000328:Adult; D001249:Asthma / Q000150:complications; D003318:Corneal Opacity / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D007644:Darier Disease / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D015228:Hypertriglyceridemia / Q000150:complications; D007676:Kidney Failure, Chronic / Q000150:complications; D008875:Middle Aged