title: Construction of 1,4-benzodiazepine skeleton from 2-(arylamino)benzamides through PhI(OAc)2-mediated oxidative C–N bond formation.
abstract: New compounds involving the biologically important 1,4-benzodiazepine skeleton were conveniently constructed from 2-(arylamino)benzamides through PhI(OAc)2-mediated oxidative C–N bond formation. The attractive features of this new synthetic strategy include mild reaction conditions, the heavy-metal-free characteristic of the oxidative coupling process, and the flexibility to tolerate a broad scope of substrates.
authors.forename: Xuming
authors.initials: X
authors.lastname: Li
authors.forename: Liu
authors.initials: L
authors.lastname: Yang
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhang
authors.forename: Daisy
authors.initials: D
authors.lastname: Zhang-Negrerie
authors.forename: Yunfei
authors.initials: Y
authors.lastname: Du
authors.forename: Kang
authors.initials: K
authors.lastname: Zhao
mesh_terms: D001549:Benzamides / Q000737:chemistry*; D001569:Benzodiazepines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D007462:Iodobenzenes / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D001549:Benzamides; D007462:Iodobenzenes; D001569:Benzodiazepines