title: Successful prevention of scedosporiosis after lung transplantation in a cystic fibrosis patient by combined local and systemic triazole therapy.
abstract: A persistent colonization with Scedosporium apiospermum (S. apiospermum) often results in disseminated infection with a high mortality rate in immunosuppressed patients. We present the first case of successful prevention of scedosporiosis in an adolescent female cystic fibrosis patient post double lung transplant, with a combination of local and systemic voriconazole therapy and surgical intervention.
authors.affiliation: Department of Pediatrics and Adolescent Medicine, Pediatric Pulmonolgy, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
authors.forename: Carolin
authors.initials: C
authors.lastname: Hartmann
authors.affiliation: Department of Pediatrics and Adolescent Medicine, Pediatric Pulmonolgy, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
authors.forename: Carsten
authors.initials: C
authors.lastname: Müller
authors.affiliation: Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
authors.forename: Hartmut
authors.initials: H
authors.lastname: Weißbrodt
authors.affiliation: Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Suerbaum
authors.affiliation: National Reference Laboratory for Pseudallescheria boydii/Scedosporium spp., Robert Koch-Institut, Berlin, Germany.
authors.forename: Kathrin
authors.initials: K
authors.lastname: Tintelnot
authors.affiliation: Department of Otolaryngology, Hannover Medical School, Hannover, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Stolle
authors.affiliation: Department of Pediatrics and Adolescent Medicine, Pediatric Pulmonolgy, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
authors.forename: Gesine
authors.initials: G
authors.lastname: Hansen
authors.affiliation: Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
authors.forename: Ludwig
authors.initials: L
authors.lastname: Sedlacek
keywords: Adolescent lung transplantation; Scedosporium apiospermum; Sinusitis; Voriconazole