title: Correlation between clonorchiasis incidences and climatic factors in Guangzhou, China.
abstract: BACKGROUND
  Human infection with Clonorchis sinensis is still a big public health problem in Guangzhou. To investigate the correlation between clonorchiasis and climatic factors, we analyzed the clonorchiasis reported cases and simultaneous meteorological data during 2006-2012 in Guangzhou City, China.
  
  
  RESULTS
  Annual incidence rate of clonorchiasis from 2006 to 2012 was 166.76, 191.55, 247.37, 213.82, 246.03, 274.71, and 239.63 (per 100 000), respectively. Each 1°C rise of temperature corresponded to an increase of 1.18% (95% CI 0.88% to 1.48%) in the monthly number of cases, and a one millimeter rise of rainfall corresponded to increase of 0.03% (95% CI 0.01% to 0.04%). Whereas each one percent rise of relative humidity corresponded to a decrease in the number of cases by 1.51% (95% CI -1.75% to -1.27%).
  
  
  CONCLUSIONS
  We reported incidence rates of clonorchiasis showed an increasing trend by years. Temperature and rainfall were positively associated with clonorchiasis incidence, while relative humidity was inversely associated with clonorchiasis incidence. Our study provided evidence that climatic factors affect the occurrence of clonorchiasis in Guangzhou city, China.
authors.forename: Tiegang
authors.initials: T
authors.lastname: Li
authors.forename: Zhicong
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Guangzhou Center for Disease Control and Prevention, Guangdong Province 510440, China. wangming@gzcdc.org.cn.
authors.forename: Ming
authors.initials: M
authors.lastname: Wang
mesh_terms: D002681:China / Q000453:epidemiology; D002980:Climate; D003003:Clonorchiasis / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D015233:Models, Statistical; D012307:Risk Factors; D012621:Seasons