title: Salivary gland tumors in Turkey: demographic features and histopathological distribution of 510 patients.
abstract: The aim of this study was to evaluate the demographic and clinicopathologic data of salivary gland tumors managed at a tertiary referral medical center in Turkey. The data of 510 patients with salivary gland tumors managed during the period of January 1984 to May 2012, were reviewed. Only primary neoplasms derived from salivary glands were included. Out of 510 neoplasms, 352 (69.0 %) were classified as benign and 158 (31.0 %) were classified as malignant. There was a male predominance and male:female ratio was 1.23 (281/229). The most common location was parotid gland (372/510, 72.9 %) followed by minor salivary glands (97/510, 19.0 %) and submandibular gland (40/510, 7.9 %). The malignancy rates were 21.5, 40.0, and 56.7 % in parotid, submandibular, and minor salivary glands locations, respectively. The most common location for minor salivary gland neoplasms was oral cavity (61/97, 62.9 %). Pleomorphic adenoma (PA) was the most common histopathological type (45.3 %) in the whole study group and also among pediatric patients. The most common malignant neoplasms were adenoid cystic carcinoma (39/510, 7.6 %) and mucoepidermoid carcinoma (5.7 %). Salivary gland tumors are more common in men. The malignancy rate is almost three times higher in neoplasms derived from minor glands when compared to parotid gland. PA is the most common histopathological tumor type in all locations and in all age groups.
authors.affiliation: Department of Otorhinolaryngology Head & Neck Surgery, School of Medicine, Gazi University, Gazi Ün. Tıp. Fak. KBB A.D, 06500 Beşevler, Ankara, Turkey.
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Kızıl
authors.affiliation: Department of Otorhinolaryngology Head & Neck Surgery, School of Medicine, Gazi University, Gazi Ün. Tıp. Fak. KBB A.D, 06500 Beşevler, Ankara, Turkey.
authors.forename: Utku
authors.initials: U
authors.lastname: Aydil
authors.affiliation: Department of Pathology, School of Medicine, Gazi University, Ankara, Turkey.
authors.forename: Ozgür
authors.initials: O
authors.lastname: Ekinci
authors.affiliation: Department of Otorhinolaryngology Head & Neck Surgery, School of Medicine, Gazi University, Gazi Ün. Tıp. Fak. KBB A.D, 06500 Beşevler, Ankara, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Dilci
authors.affiliation: Department of Otorhinolaryngology Head & Neck Surgery, School of Medicine, Gazi University, Gazi Ün. Tıp. Fak. KBB A.D, 06500 Beşevler, Ankara, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Köybaşıoğlu
authors.affiliation: Department of Otorhinolaryngology Head & Neck Surgery, School of Medicine, Gazi University, Gazi Ün. Tıp. Fak. KBB A.D, 06500 Beşevler, Ankara, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Düzlü
authors.affiliation: Department of Otorhinolaryngology Head & Neck Surgery, School of Medicine, Gazi University, Gazi Ün. Tıp. Fak. KBB A.D, 06500 Beşevler, Ankara, Turkey.
authors.forename: Erdoğan
authors.initials: E
authors.lastname: Inal
keywords: Adenoma, pleomorphic; Carcinoma, adenoid cystic; Neoplasms; Parotid gland; Salivary glands