title: [Progress in biotransformation of bio-based lactic acid ].
abstract: Fermentative production of lactic acid, an important bio-based chemicals, has made considerable progress. In addition to the food industry and production of polylactic acid, lactic acid also can be used as an important platform chemical for the production of acrylic acid, pyruvic acid, 1,2-propanediol, and lactic acid esters. This article summarizes the recent progress in biocatalytic production of lactic acid derivatives by dehydration, dehydrogenation, reduction, and esterification. Trends in the biotransformation of lactic acid are also discussed.
authors.affiliation: State Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Jinan 250100, Shandong, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Gao
authors.affiliation: State Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Jinan 250100, Shandong, China.
authors.forename: Cuiqing
authors.initials: C
authors.lastname: Ma
authors.affiliation: State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Xu
mesh_terms: D000179:Acrylates / Q000378:metabolism; D001419:Bacteria / Q000235:genetics / Q000378:metabolism; D001709:Biotechnology / Q000379:methods*; D001711:Biotransformation; D005285:Fermentation; D007218:Industrial Microbiology / Q000379:methods; D019344:Lactic Acid / Q000378:metabolism*; D019946:Propylene Glycol / Q000378:metabolism; D019289:Pyruvic Acid / Q000378:metabolism; D015003:Yeasts / Q000235:genetics / Q000378:metabolism
chemical_list: D000179:Acrylates; D019344:Lactic Acid; D019946:Propylene Glycol; D019289:Pyruvic Acid; C036658:acrylic acid