title: ACEF and clinical SYNTAX score in the risk stratification of patients with heavily calcified coronary stenosis undergoing rotational atherectomy with stent implantation.
abstract: OBJECTIVE
  To assess ACEF (age, creatinine, and ejection fraction) and Clinical SYNTAX (CSS) score in the risk stratification of patients with heavily calcified stenosis undergoing rotational atherectomy with stent implantation (rota-stenting).
  
  
  RESULTS
  ACEF and CSS were calculated in 221 consecutive patients with stable angina undergoing rota-stenting. Mean age of the patients was 74 ± 10 years, left ventricular ejection fraction was 61 ± 18%, and final burr size 1.78 ± 0.24 mm, with 2.6 ± 0.9 burrs used for each patient. Primary end-point was MACE at one-year defined as the composite of cardiac death, myocardial infarction, and target vessel revascularization. Post-hoc analysis was performed by stratifying the clinical outcome according to ACEF and CSS tertiles. At 1 year there was a significantly higher MACE rate in the high tertile of ACEF (24% for ACEFHigh vs. 13% for ACEFMid vs. 9% for ACEFLow; P = 0.017) and CSS (25% for CSSHigh vs. 12% for CSSMid vs. 8% for CSSLow; P = 0.008). The predictive accuracy for both ACEF and CSS was moderate (c-statistics, 0.629 and 0.638, respectively).
  
  
  CONCLUSIONS
  Both ACEF and CSS predict with moderate accuracy MACE at 1-year in patients with heavily calcified coronary stenosis undergoing rotational atherectomy with stent implantation.
authors.affiliation: Cardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
authors.forename: Stylianos A
authors.initials: SA
authors.lastname: Pyxaras
authors.forename: Fabio
authors.initials: F
authors.lastname: Mangiacapra
authors.forename: William
authors.initials: W
authors.lastname: Wijns
authors.forename: Luigi
authors.initials: L
authors.lastname: Di Serafino
authors.forename: Frederic
authors.initials: F
authors.lastname: De Vroey
authors.forename: Gabor
authors.initials: G
authors.lastname: Toth
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Sinagra
authors.forename: Bernard
authors.initials: B
authors.lastname: De Bruyne
authors.forename: Guy R
authors.initials: GR
authors.lastname: Heyndrickx
authors.forename: Emanuele
authors.initials: E
authors.lastname: Barbato
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017225:Atherectomy, Coronary / Q000379:methods*; D001530:Belgium / Q000453:epidemiology; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000601:surgery*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D003331:Coronary Vessels / Q000601:surgery*; D003404:Creatinine / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D011183:Postoperative Complications / Q000097:blood / Q000453:epidemiology* / Q000503:physiopathology; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D012720:Severity of Illness Index; D015607:Stents; D013318:Stroke Volume; D016277:Ventricular Function, Left
chemical_list: D003404:Creatinine
keywords: ACEF score; calcified coronary stenosis; clinical SYNTAX score; major adverse cardiovascular events; rotational atherectomy