title: [Biomarkers in multiple sclerosis (a review and experimental data)].
abstract: Identification of biomarkers in multiple sclerosis is a very complex problem, and intensive work is being made in this field for the last decades. The importance of establishing biomarkers of multiple sclerosis is related to the high disease heterogeneity and lack of characteristic symptoms that leads to diagnostic, prognostic challenges and difficulties in making decisions about therapy. In this paper, we review the most important biomarkers and discuss their diagnostic and prognostic value. Experimental results on neurofilament heavy chains and antibodies to sulfatide in multiple sclerosis are presented.
authors.forename: A A
authors.initials: AA
authors.lastname: Vorob'eva
authors.forename: M V
authors.initials: MV
authors.lastname: Ivanova
authors.forename: V V
authors.initials: VV
authors.lastname: Fominykh
authors.forename: M N
authors.initials: MN
authors.lastname: Zakharova
authors.forename: N A
authors.initials: NA
authors.lastname: Zigangirova
authors.forename: N V
authors.initials: NV
authors.lastname: Guliaeva
mesh_terms: D000328:Adult; D000906:Antibodies / Q000097:blood / Q000276:immunology; D015415:Biomarkers / Q000097:blood*; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D011379:Prognosis; D013433:Sulfoglycosphingolipids / Q000097:blood* / Q000276:immunology
chemical_list: D000906:Antibodies; D015415:Biomarkers; D013433:Sulfoglycosphingolipids