title: Comparison of central corneal thickness measured by hand-held and desk-mounted ultrasound pachymeters in glaucoma patients.
abstract: OBJECTIVE
  The purpose of this study was to compare the accuracy and reproducibility of central corneal thickness measured by hand-held and desk-mounted ultrasound pachymeter in glaucoma patients under treatment.
  
  
  METHODS
  Prospective study of 65 glaucoma patients. Central corneal thickness was measured by two ultrasound pachymeters: the hand-held, portable PachPen (Accutome, Lynwood, WA), and the desk-mounted PacScan 300 (Sonomed, Lake Success, NY).
  
  
  RESULTS
  The mean ± SD central corneal thickness was 526.5 ± 44.8 µm and 530.0 ± 44.7 µm for the hand-held and desk-mounted pachymeters, respectively (p = 0.15). Linear regression analysis revealed a slope of 0.97 with Pearson correlation coefficient of 0.96. Bland-Altman analysis showed a mean difference of measurements by both pachymeters of 3.22 µm with two standard deviations = 9.51. Both instruments showed high intraobserver correlation: 0.972 for the hand-held pachymeter and 0.993 for the desk-mounted pachymeter.
  
  
  CONCLUSIONS
  Central corneal thickness measurements were comparable with the use of hand-held and desk-mounted ultrasound units in glaucoma patients with good intraobserver reproducibility.
authors.affiliation: University of Tennessee Health Science Center , Memphis, TN , USA.
authors.forename: Sarwat
authors.initials: S
authors.lastname: Salim
authors.forename: Haiming
authors.initials: H
authors.lastname: Du
authors.forename: Jim
authors.initials: J
authors.lastname: Wan
mesh_terms: D000368:Aged; D003315:Cornea / Q000473:pathology*; D063171:Corneal Pachymetry / Q000295:instrumentation* / Q000379:methods; D005260:Female; D005902:Glaucoma, Open-Angle / Q000150:complications*; D006801:Humans; D057066:Low Tension Glaucoma / Q000150:complications*; D008297:Male; D015588:Observer Variation; D009798:Ocular Hypertension / Q000150:complications; D009929:Organ Size; D011446:Prospective Studies; D015203:Reproducibility of Results
keywords: Central corneal thickness; desk-mounted PacScan pachymeter; glaucoma; hand-held PachPen pachymeter; ultrasound pachymetry