title: Yttrium-90 radioembolization of liver tumors: what do the images tell us?
abstract: Transarterial radioembolization (TARE) with yttrium 90 microspheres is an increasingly popular therapy for both primary and secondary liver malignancies. TARE entails delivery of β-particle brachytherapy and embolization of the tumor vasculature. The consequent biological sequelae are distinct from those of other transarterial therapies for liver tumors, as reflected in the often baffling post-treatment imaging features. As the clinical use of TARE is increasing, more diverse post-treatment radiological findings are encountered with variable overlap among treatment response, residual disease, reactionary changes and complications. Thus, post-TARE image interpretation is challenging. This review provides a comprehensive description of the different findings seen in post-treatment scans, with the aim of facilitating appropriate radiological interpretation of post-TARE pathologic changes, notwithstanding their existing limitations.
authors.affiliation: Department of Diagnostic Imaging, National University Hospital and Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Pavel
authors.initials: P
authors.lastname: Singh
authors.affiliation: Department of Diagnostic Imaging, National University Hospital and Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Gopinathan
authors.initials: G
authors.lastname: Anil
mesh_terms: D038524:Diffusion Magnetic Resonance Imaging; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods*; D019788:Fluorodeoxyglucose F18; D005767:Gastrointestinal Diseases / Q000209:etiology; D006801:Humans; D008100:Liver Abscess / Q000209:etiology; D008113:Liver Neoplasms / Q000532:radiotherapy*; D064847:Multimodal Imaging; D016066:Pleural Effusion, Malignant / Q000209:etiology; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D015021:Yttrium Radioisotopes / Q000008:administration & dosage*
chemical_list: D015021:Yttrium Radioisotopes; D019788:Fluorodeoxyglucose F18