title: [Advance on Escherichia coli alpha-hemolysin secretion pathway---a review].
abstract: In recent years, with the development of biotechnology, the molecular mechanism of the secretion pathways in Escherichia coli is clearer and clearer, and it becomes one of the most effective methods to use E. coli expression system for extracellular production of recombinant proteins. This review discusses recent advances in the secretion mechanism and application of E. coli alpha-hemolysin secretion pathway.
authors.affiliation: State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China. sulingqia@126.com
authors.forename: Lingqia
authors.initials: L
authors.lastname: Su
authors.affiliation: State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Wu
mesh_terms: D000818:Animals; D058947:Bacterial Secretion Systems; D004926:Escherichia coli / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D004927:Escherichia coli Infections / Q000382:microbiology; D029968:Escherichia coli Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D006460:Hemolysin Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D017510:Protein Folding
chemical_list: D058947:Bacterial Secretion Systems; D029968:Escherichia coli Proteins; D006460:Hemolysin Proteins; C036507:Hlya protein, E coli