title: Technical requirements for Na¹⁸F PET bone imaging of patients being treated using a Taylor spatial frame.
abstract: Diagnosis of new bone growth in patients with compound tibia fractures or deformities treated using a Taylor spatial frame is difficult with conventional radiography because the frame obstructs the images and creates artifacts. The use of Na(18)F PET studies may help to eliminate this difficulty.
  
  
  METHODS
  Patients were positioned on the pallet of a clinical PET/CT scanner and made as comfortable as possible with their legs immobilized. One bed position covering the site of the fracture, including the Taylor spatial frame, was chosen for the study. A topogram was performed, as well as diagnostic and attenuation correction CT. The patients were given 2 MBq of Na(18)F per kilogram of body weight. A 45-min list-mode acquisition was performed starting at the time of injection, followed by a 5-min static acquisition 60 min after injection. The patients were examined 6 wk after the Taylor spatial frame had been applied and again at 3 mo to assess new bone growth.
  
  
  RESULTS
  A list-mode reconstruction sequence of 1 × 1,800 and 1 × 2,700 s, as well as the 5-min static scan, allowed visualization of regional bone turnover.
  
  
  CONCLUSIONS
  With Na(18)F PET/CT, it was possible to confirm regional bone turnover as a means of visualizing bone remodeling without the interference of artifacts from the Taylor spatial frame. Furthermore, dynamic list-mode acquisition allowed different sequences to be performed, enabling, for example, visualization of tracer transport from blood to the fracture site.
authors.affiliation: Department of Nuclear Medicine, Karolinska University Hospital, Stockholm, Sweden.
authors.forename: Robert
authors.initials: R
authors.lastname: Hatherly
authors.forename: Fredrik
authors.initials: F
authors.lastname: Brolin
authors.forename: Åsa
authors.initials: Å
authors.lastname: Oldner
authors.forename: Anders
authors.initials: A
authors.lastname: Sundin
authors.forename: Henrik
authors.initials: H
authors.lastname: Lundblad
authors.forename: Gerald Q
authors.initials: GQ
authors.lastname: Maguire
authors.forename: Cathrine
authors.initials: C
authors.lastname: Jonsson
authors.forename: Hans
authors.initials: H
authors.lastname: Jacobsson
authors.forename: Marilyn E
authors.initials: ME
authors.lastname: Noz
mesh_terms: D000328:Adult; D016477:Artifacts; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D019047:Phantoms, Imaging; D049268:Positron-Emission Tomography / Q000379:methods*; D012969:Sodium Fluoride; D012979:Sodium Radioisotopes
chemical_list: D012979:Sodium Radioisotopes; D012969:Sodium Fluoride
keywords: Na18F; PET/CT; Taylor spatial frame; bone imaging