title: Does parental body mass index status modify the associations among birth weight, early growth and childhood adiposity?
abstract: OBJECTIVE
  To examine the associations among birth weight, infant growth and childhood adiposity, and to test whether parental weight status modifies these associations.
  
  
  METHODS
  The sample was comprised of 423 participants born at term who were an appropriate size for their gestational age from the Quebec Adipose and Lifestyle Investigation in Youth (QUALITY) study, a cohort of 630 children with a parental history of obesity. Infant growth velocity from zero to two years of age was estimated using slopes from simple linear regression for weight and body mass index (BMI) Z-scores. Child anthropometrics and body composition, and parental BMI were measured from eight to 10 years of age. Associations were modelled using multiple linear regressions.
  
  
  RESULTS
  Increased birth weight and growth velocity independently predicted increased childhood adiposity. Effects of infant growth velocity on later adiposity were stronger with higher maternal BMI but not with higher paternal BMI. Similar interactions with birth weight were not found.
  
  
  CONCLUSIONS
  Early childhood measures of growth and the mother's BMI score should be included in investigations on obesity risk.
authors.affiliation: Département de pédiatrie, Service de génétique médicale, Centre Hospitalier Universitaire (CHU) Sainte-Justine and Université de Montréal;
authors.forename: Lilianne
authors.initials: L
authors.lastname: Gómez-López
authors.affiliation: Département de médecine sociale et préventive, Université de Montréal; ; Centre de recherche du Centre Hospitalier Universitaire (CHU) Sainte-Justine;
authors.forename: Andraea
authors.initials: A
authors.lastname: Van Hulst
authors.affiliation: Centre de recherche du Centre Hospitalier Universitaire (CHU) Sainte-Justine; ; Department of Exercise Science, Concordia University, Montréal;
authors.forename: Tracie A
authors.initials: TA
authors.lastname: Barnett
authors.affiliation: Département de médecine sociale et préventive, Université de Montréal; ; Centre de recherche du Centre Hospitalier Universitaire (CHU) Sainte-Justine;
authors.forename: Marie-Hélène
authors.initials: MH
authors.lastname: Roy-Gagnon
authors.affiliation: Department of Kinesiology, Université Laval, Quebec City;
authors.forename: Angelo
authors.initials: A
authors.lastname: Tremblay
authors.affiliation: Département de médecine sociale et préventive, Université de Montréal; ; Institut national de sante publique de Quebec; ; Centre de recherche du Centre Hospitalier Universitaire de Montréal (CRCHUM), Montréal, Quebec.
authors.forename: Jennifer
authors.initials: J
authors.lastname: O'Loughlin
authors.affiliation: Département de pédiatrie, Service de génétique médicale, Centre Hospitalier Universitaire (CHU) Sainte-Justine and Université de Montréal; ; Centre de recherche du Centre Hospitalier Universitaire (CHU) Sainte-Justine;
authors.forename: Marie
authors.initials: M
authors.lastname: Lambert
keywords: Adiposity; Body mass index; Cohort study; Dual-energy x-ray absorptiometry; Parents; Weight gain