title: In situ 111In-doping for achieving biocompatible and non-leachable 111In-labeled Fe3O4 nanoparticles.
abstract: The present study reports a new approach for synthesizing (111)In-radiolabeled biocompatible Fe3O4 nanoparticles. Radioactive (111)In is doped in situ into the lattice of Fe3O4 nanoparticles to achieve robust radiolabeling for accurately tracing PEGylated Fe3O4 particles in vivo.
authors.affiliation: Institute of Chemistry, Chinese Academy of Sciences, Bei Yi Jie 2, Zhong Guan Cun, Beijing 100190, China. gaomy@iccas.ac.cn.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Zeng
authors.forename: Bing
authors.initials: B
authors.lastname: Jia
authors.forename: Ruirui
authors.initials: R
authors.lastname: Qiao
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
authors.forename: Lihong
authors.initials: L
authors.lastname: Jing
authors.forename: Fan
authors.initials: F
authors.lastname: Wang
authors.forename: Mingyuan
authors.initials: M
authors.lastname: Gao
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry* / Q000493:pharmacokinetics; D003287:Contrast Media / Q000138:chemical synthesis / Q000737:chemistry / Q000493:pharmacokinetics; D052203:Ferrosoferric Oxide / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007205:Indium Radioisotopes / Q000737:chemistry; D007553:Isotope Labeling; D008279:Magnetic Resonance Imaging; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry* / Q000378:metabolism; D010316:Particle Size; D011092:Polyethylene Glycols / Q000737:chemistry; D014018:Tissue Distribution
chemical_list: D001672:Biocompatible Materials; D003287:Contrast Media; D007205:Indium Radioisotopes; D011092:Polyethylene Glycols; D052203:Ferrosoferric Oxide