title: Synthesis and antioxidant properties of gum arabic-stabilized selenium nanoparticles.
abstract: Selenium nanoparticles (SeNPs) were prepared by using gum arabic (GA) as the stabilizer in a facile synthetic approach. The size, morphology, stability and antioxidant activity in vitro of the gum arabic-selenium nanocomposites (GA-SeNPs) were characterized by transmission electron microscopy (TEM), dynamic light scattering (DLS), Fourier-transform infrared spectroscopy (FTIR), atomic force microscopy (AFM) and ultraviolet-visible spectrophotometry (UV-vis). SeNPs (particle size of ∼34.9 nm) can be stabilized in gum arabic aqueous solutions for approximately 30 days. FTIR results show that SeNPs were combined to the hydroxyl groups of GA. In the present work, the alkali-hydrolyzed GA (AHGA) was also prepared and its efficiency in stabilizing SeNPs was compared with GA. It was concluded that the branched structure of GA was a significant factor for the functionality. The hydroxyl radical scavenging ability and DPPH scavenging ability of GA-SeNPs were higher than those of AHGA-SeNPs and could reach 85.3±2.6%, 85.3±1.9% at a concentration of 4 mg/ml, respectively.
authors.affiliation: Glyn O. Phillips Hydrocolloid Research Centre at HUT, School of Food and Pharmaceutical Engineering, Faculty of Light Industry, Hubei University of Technology, Wuhan 430068, China.
authors.forename: Huiling
authors.initials: H
authors.lastname: Kong
authors.affiliation: Department of Chemistry, Glyndwr University, Plas Coch, Mold Road, Wrexham LL11 2AW, UK.
authors.forename: Jixin
authors.initials: J
authors.lastname: Yang
authors.affiliation: Glyn O. Phillips Hydrocolloid Research Centre at HUT, School of Food and Pharmaceutical Engineering, Faculty of Light Industry, Hubei University of Technology, Wuhan 430068, China.
authors.forename: Yifeng
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Glyn O. Phillips Hydrocolloid Research Centre at HUT, School of Food and Pharmaceutical Engineering, Faculty of Light Industry, Hubei University of Technology, Wuhan 430068, China; Department of Chemistry, Glyndwr University, Plas Coch, Mold Road, Wrexham LL11 2AW, UK. Electronic address: y.fang@glyndwr.ac.uk.
authors.forename: Yapeng
authors.initials: Y
authors.lastname: Fang
authors.affiliation: Glyn O. Phillips Hydrocolloid Research Centre at HUT, School of Food and Pharmaceutical Engineering, Faculty of Light Industry, Hubei University of Technology, Wuhan 430068, China.
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Nishinari
authors.affiliation: Glyn O. Phillips Hydrocolloid Research Centre at HUT, School of Food and Pharmaceutical Engineering, Faculty of Light Industry, Hubei University of Technology, Wuhan 430068, China; Glyn O. Phillips Hydrocolloid Research Center, Glyndwr University, Plas Coch, Mold Road, Wrexham LL11 2AW, UK.
authors.forename: Glyn O
authors.initials: GO
authors.lastname: Phillips
mesh_terms: D004355:Drug Stability; D016166:Free Radical Scavengers / Q000138:chemical synthesis* / Q000737:chemistry*; D006170:Gum Arabic / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D053758:Nanoparticles / Q000737:chemistry*; D012643:Selenium / Q000737:chemistry*
chemical_list: D016166:Free Radical Scavengers; D006170:Gum Arabic; D012643:Selenium
keywords: Antioxidant; Gum arabic; Selenium nanoparticles