title: Morphometric parameters of peripheral nerves in calves correlated with conduction velocity.
abstract: BACKGROUND
  Peripheral nerve injuries are the most frequent neurologic disorder in cattle. So far, no physiologic values have been established for the motor nerve conduction velocity (mNCV) in this precocial species.
  
  
  OBJECTIVE
  The electrophysiologic and morphometric reference values of peripheral nerves in calves were determined. It was hypothesized that these parameters would correlate to the high degree of maturity in the first days of life in this species compared to other species.
  
  
  METHODS
  Twenty-six healthy calves were used in this study.
  
  
  METHODS
  The mNCV of the radial and the sciatic/common peroneal nerve was measured in all 26 calves. Nerve biopsies from a group of 6 calves were taken to correlate the obtained electrophysiologic data with morphological parameters.
  
  
  RESULTS
  The mean mNCV of the radial nerve was 48.3 ± 10.6 m/s, whereas the mean mNCV of the sciatic/peroneal nerve was with 83.8 ± 5.9 m/s significantly faster (P < .0001). The average fiber diameter was 8.40 ± 2.80 μm (range, 1.98-17.90 μm) and the average g-ratio was 0.61 ± 0.04 SD.
  
  
  CONCLUSIONS
  The established reference values for mNCV in calves correlate well with the evaluated morphometric parameters. Attributable to their comparably fast mNCV and high fiber diameters, juvenile calves appear to be much more mature individuals than other mammals. Electrophysiologic characterization of peripheral nerve injury now is feasible in this species.
authors.affiliation: Department of Small Animal Medicine and Surgery, University of Veterinary Medicine, Hannover, Germany; Center for Systems Neuroscience (ZSN), Hannover, Germany.
authors.forename: H C
authors.initials: HC
authors.lastname: Schenk
authors.forename: K
authors.initials: K
authors.lastname: Haastert-Talini
authors.forename: J
authors.initials: J
authors.lastname: Jungnickel
authors.forename: C
authors.initials: C
authors.lastname: Grothe
authors.forename: H
authors.initials: H
authors.lastname: Meyer
authors.forename: J
authors.initials: J
authors.lastname: Rehage
authors.forename: M
authors.initials: M
authors.lastname: Fehr
authors.forename: J
authors.initials: J
authors.lastname: Bokemeyer
authors.forename: C
authors.initials: C
authors.lastname: Rohn
authors.forename: A
authors.initials: A
authors.lastname: Tipold
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000033:anatomy & histology / Q000502:physiology; D002417:Cattle / Q000033:anatomy & histology* / Q000502:physiology; D009431:Neural Conduction / Q000502:physiology*; D010525:Peripheral Nerves / Q000033:anatomy & histology* / Q000502:physiology; D010543:Peroneal Nerve / Q000033:anatomy & histology / Q000502:physiology; D012584:Sciatic Nerve / Q000033:anatomy & histology / Q000502:physiology
keywords: Myelination; Precocial species; g-ratio