title: From stillness to motion: 80 years after the first description of Taenia solium oncosphere hatching.
abstract: BACKGROUND
  Human neurocysticercosis (NCC) is a considered public health problem in many underdeveloped and developing countries. Because of the enormous increase in international tourism and migration, NCC nowadays is also found in some developed countries. Our group was the first to demonstrate that tapeworm carriers in the household are the main risk factor for acquiring cysticercosis in humans and pigs, since the disease results from the ingestion of microscopic tapeworm eggs.
  
  
  RESULTS
  We had the opportunity to film the liberation of the embryo from the oncospheral membrane after the hatching of the egg, which is the activation process required for intestinal wall invasion by the onchosphere. Yoshino (J Formosa Med Ass 32:139-142, 1933) described with great detail in diagrams and photographs this process eighty years ago after he infected himself with three living cysticerci in order to study the life cycle of Taenia solium. Other authors further described this process. Nevertheless it has never been filmed before. The purpose of this paper is to shift from stillness to motion since we can now show for the first time a movie of an activated oncosphere and its release from the oncospheral membrane.
  
  
  CONCLUSIONS
  Oncospheral activation is the requisite for T. solium embryos to invade the intestinal mucosa and develop into cysticerci. This process has been amply described but here it is shown for the first time in motion; thus it may be of interest for readers of the journal and useful for educational purposes towards the control of NCC.
authors.forename: Fela
authors.initials: F
authors.lastname: Mendlovic
authors.forename: Adriana
authors.initials: A
authors.lastname: Garza-Rodríguez
authors.forename: Joaquin
authors.initials: J
authors.lastname: Carrillo-Farga
authors.forename: Fernando
authors.initials: F
authors.lastname: González-Domínguez
authors.forename: Pablo
authors.initials: P
authors.lastname: Maravilla
authors.affiliation: Facultad de Medicina, Universidad Nacional Autónoma de México, México 04510 DF, Mexico. flisser@unam.mx.
authors.forename: Ana
authors.initials: A
authors.lastname: Flisser
mesh_terms: D000818:Animals; D006801:Humans; D008853:Microscopy; D020019:Neurocysticercosis / Q000469:parasitology*; D041201:Taenia solium / Q000254:growth & development / Q000302:isolation & purification*