title: Fiber bundle endocytoscopy.
abstract: Endocytoscopy is an optical biopsy technique which uses a miniaturized camera to capture white light microscopy images through an endoscope. We have developed an alternative design that instead relays images to an external camera via a coherent fiber bundle. In this paper we characterize the device and demonstrate microscopy of porcine tissue ex vivo. One advantage of our approach is the ease with which other bundle-compatible imaging modalities can be deployed simultaneously. We show this by acquiring quasi-simultaneous endocytoscopy and fluorescence confocal endomicroscopy images through a single fiber bundle. This opens up possibilities for multi-modal endomicroscopy, combining white light and fluorescence imaging.
authors.affiliation: The Hamlyn Centre for Robotic Surgery, Imperial College London, South Kensington Campus, London. SW2 2AZ. UK ; Department of Computing, Imperial College London UK.
authors.forename: Michael
authors.initials: M
authors.lastname: Hughes
authors.affiliation: The Hamlyn Centre for Robotic Surgery, Imperial College London, South Kensington Campus, London. SW2 2AZ. UK ; Department of Surgery and Cancer, Imperial College London UK.
authors.forename: Tou Pin
authors.initials: TP
authors.lastname: Chang
authors.affiliation: The Hamlyn Centre for Robotic Surgery, Imperial College London, South Kensington Campus, London. SW2 2AZ. UK ; Department of Computing, Imperial College London UK.
authors.forename: Guang-Zhong
authors.initials: GZ
authors.lastname: Yang
keywords: (110.0180) Microscopy; (170.2150) Endoscopic imaging