title: Synthesis of polysubstituted pyrroles via [3 + 2]-annulation of aziridines and β-nitroalkenes under aerobic conditions.
abstract: Polysubstituted pyrroles were regioselectively synthesized in moderate to good yields via the copper acetate-catalyzed [3 + 2] annulation reaction of readily accessible aziridines and nitroalkenes. This reaction was proposed to proceed through a key azomethine ylide intermediate generated by selective C-C bond cleavage of the aziridine followed by annulation with nitroalkenes under aerobic conditions.
authors.affiliation: Department of Chemistry, Wannan Medical College, Wuhu, Anhui 241002, P. R. China.
authors.forename: Shaoyin
authors.initials: S
authors.lastname: Wang
authors.forename: Xiancui
authors.initials: X
authors.lastname: Zhu
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Chai
authors.forename: Shaowu
authors.initials: S
authors.lastname: Wang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D009574:Nitro Compounds / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D001388:Aziridines; D009574:Nitro Compounds; D011758:Pyrroles; C033132:aziridine; D003300:Copper