title: The laparoscopic nissen fundoplication eliminates obstructive sleep apnea syndrome due to gastroesophageal reflux disease.
abstract: Gastroesophageal reflux disease may produce esophageal syndromes, such as heartburn and regurgitation. It is a common clinical presentation with extraesophageal manifestations, such as asthma, arrhythmia, snoring, and sleep disturbance, which could make identifying it more difficult than the usual esophageal symptoms. The aim of this study is to characterize the extraesophageal manifestations in patients with gastroesophageal reflux disease and investigate the effect of laparoscopic Nissen fundoplication. We describe the case of a 38-year-old male patient with a history of sleep disturbance attributable to gastroesophageal reflux disease, which resolved on successful laparoscopic Nissen fundoplication treatment. The long-standing sleep apnea obviously improved after laparoscopic Nissen fundoplication treatment. To our knowledge, this is a rare case of successful laparoscopic Nissen fundoplication treatment of a patient with extraesophageal manifestations induced by gastroesophageal reflux disease. The results indicate an underlying mechanism for extraesophageal manifestations and the success of laparoscopic Nissen fundoplication treatment.
authors.affiliation: Thoracic & Cardiovascular Surgery, Xuan Wu Hospital, Capital Medical University, No. 45 Changchun Street, Beijing, 100053 People's Republic of China.
authors.forename: Cheng-Chao
authors.initials: CC
authors.lastname: Zhang
authors.affiliation: Thoracic & Cardiovascular Surgery, Xuan Wu Hospital, Capital Medical University, No. 45 Changchun Street, Beijing, 100053 People's Republic of China ; Center for GERD of Er Pao General Hospital, Beijing, People's Republic of China.
authors.forename: Zhong-Gao
authors.initials: ZG
authors.lastname: Wang
authors.affiliation: Center for GERD of Er Pao General Hospital, Beijing, People's Republic of China.
authors.forename: Ji-Min
authors.initials: JM
authors.lastname: Wu
authors.affiliation: Thoracic & Cardiovascular Surgery, Xuan Wu Hospital, Capital Medical University, No. 45 Changchun Street, Beijing, 100053 People's Republic of China.
authors.forename: Feng
authors.initials: F
authors.lastname: Ji
authors.affiliation: Thoracic & Cardiovascular Surgery, Xuan Wu Hospital, Capital Medical University, No. 45 Changchun Street, Beijing, 100053 People's Republic of China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Gao
authors.affiliation: Thoracic & Cardiovascular Surgery, Xuan Wu Hospital, Capital Medical University, No. 45 Changchun Street, Beijing, 100053 People's Republic of China.
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Hu
keywords: Gastroesophageal reflux disease; Laparoscopic Nissen fundoplication; Obstructive sleep apnea syndrome