title: [Treatment of infected diabetic foot ulcers clinical effectiveness of a dressing of alginate and hydrocolloid, with silver fiber. Analysis of results of a series of cases].
abstract: BACKGROUND
  High levels of bacterial load have shown a deleterious influence on wound healing. Using antimicrobial dressings can control ulcers' bioburden. The aim of our study was to evaluate the improving of infected diabetic foot ulcers due an alginate's fiber and hydrocolloid silver dressing.
  
  
  METHODS
  We analysed a case series of 6 patients with diabetic foot ulcers without peripheral vascular disease and diagnosed from critical colonization and/or local infection according the presence of inflammation clinical signs. Patients were treated for a minimum period of two weeks. We analysed the percentage reduction in ulcer area from the day of enrolment to antimicrobial dressing removal.
  
  
  RESULTS
  The duration of treatment had a median of 5 weeks with a minimum of 2 weeks and up to 6. The median percentage of area reduction of the wounds was 47.7% (range: 0.5%-90%). The mean percentage reduction on the lesion was 58% from 2 weeks and 67.14% at 3 weeks. All patients had reduced significantly their size at 3 weeks from beginning of treatment (p < 0.05).
  
  
  CONCLUSIONS
  The use of an alginate's fiber and hydrocolloid silver dressing promotes healing on diabetic foot ulcers with local infection, reducing the inflammatory clinical signs significantly over a period of three weeks.
authors.affiliation: Unidad de Pie Diabético de la Universidad Complutense de Madrid.
authors.forename: J L
authors.initials: JL
authors.lastname: Lázaro-Martínez
authors.affiliation: Unidad de Pie Diabético de la Universidad Complutense de Madrid.
authors.forename: A
authors.initials: A
authors.lastname: Cecilia-Matilla
authors.affiliation: Unidad de Pie Diabético del Hospital La Paloma de Las Palmas de Gran Canaria.
authors.forename: J
authors.initials: J
authors.lastname: Aragón-Sánchez
authors.affiliation: Unidad de Pie Diabético de la Universidad Complutense de Madrid.
authors.forename: E
authors.initials: E
authors.lastname: García-Morales
authors.affiliation: Unidad de Pie Diabético de la Universidad Complutense de Madrid.
authors.forename: Y
authors.initials: Y
authors.lastname: Garcia-Alvarez
authors.affiliation: Unidad de Pie Diabético de la Universidad Complutense de Madrid.
authors.forename: F
authors.initials: F
authors.lastname: Alvaro-Afonso
mesh_terms: D000368:Aged; D000464:Alginates / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000150:complications* / Q000188:drug therapy*; D001458:Bandages; D001672:Biocompatible Materials / Q000627:therapeutic use*; D003102:Colloids / Q000627:therapeutic use*; D017719:Diabetic Foot / Q000150:complications*; D005260:Female; D020723:Glucuronic Acid / Q000627:therapeutic use; D006603:Hexuronic Acids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D018030:Silver Compounds / Q000627:therapeutic use*; D014945:Wound Healing
chemical_list: D000464:Alginates; D001672:Biocompatible Materials; D003102:Colloids; D006603:Hexuronic Acids; D018030:Silver Compounds; D020723:Glucuronic Acid