title: Is single dose povidone iodine sclerotherapy effective in chyluria?
abstract: OBJECTIVE
  To evaluate the effectiveness and safety of single dose 0.2 % povidone iodine renal pelvic instillation sclerotherapy for the treatment for chyluria.
  
  
  METHODS
  In a prospective study from August 2010 till July 2013, 41 patients presenting with milky urine were included. Apart from ether test, the presence of lymphocytes in urine and urine triglycerides levels were also done to confirm chyluria. On a day care basis under local anesthesia, 5F open-ended ureteric catheter was introduced in the ureteric orifice of affected side. Freshly prepared 7-10 ml of 0.2 % povidone iodine solution was instilled with the patient in Trendelenburg position.
  
  
  RESULTS
  Total of 41 patients were enrolled (27 males and 14 females; mean age 40 years, SD 8.9, range 19-61) with a mean follow-up of 20 months. Immediate clearance was seen in all patients and recurrence in 7 (17 %). Mean disease-free duration was 18 months. Two patients had moderate to severe flank pain.
  
  
  CONCLUSIONS
  Single dose 0.2 % povidone iodine sclerotherapy is safe and effective treatment for chyluria. As it offers treatment on a day care basis, continuous ureteral and urethral catheterizations can be avoided.
authors.affiliation: Urology Unit, Department of Surgery, Bir Hospital, National Academy of Medical Sciences, Kathmandu, Nepal, anyl77@hotmail.com.
authors.forename: Anil
authors.initials: A
authors.lastname: Shrestha
authors.forename: Parash Mani
authors.initials: PM
authors.lastname: Shrestha
authors.forename: Rakesh
authors.initials: R
authors.lastname: Verma
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000009:adverse effects; D002913:Chyle; D018572:Disease-Free Survival; D005260:Female; D021501:Flank Pain / Q000139:chemically induced; D006801:Humans; D007322:Instillation, Drug; D007682:Kidney Pelvis; D008297:Male; D008875:Middle Aged; D011206:Povidone-Iodine / Q000008:administration & dosage* / Q000009:adverse effects; D011446:Prospective Studies; D012008:Recurrence; D015911:Sclerotherapy / Q000009:adverse effects / Q000379:methods*; D014556:Urine; D055815:Young Adult
chemical_list: D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine