title: Fast gradient-encoded CEST spectroscopy of hyperpolarized xenon.
abstract: Breaking speed limits: The acquisition of xenon-129 Hyper-CEST spectra is drastically accelerated by utilizing gradients to encode the chemical shift dimension. The signal is increased by using repeated spin-echo refocussing. The additional application of a variable flip angle makes the experiment independent from a constant Xe redelivery.
authors.affiliation: Leibniz-Institut für Molekulare Pharmakologie, Robert-Rössle-Str. 10, 13125 Berlin (Germany).
authors.forename: Jörg
authors.initials: J
authors.lastname: Döpfert
authors.forename: Christopher
authors.initials: C
authors.lastname: Witte
authors.forename: Leif
authors.initials: L
authors.lastname: Schröder
mesh_terms: D003287:Contrast Media / Q000737:chemistry; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D011083:Polycyclic Compounds / Q000737:chemistry; D014978:Xenon / Q000737:chemistry*
chemical_list: D003287:Contrast Media; D011083:Polycyclic Compounds; C545484:cryptophane A; D014978:Xenon
keywords: cest agents; hyper-cest; hyperpolarized xenon; nmr spectroscopy; ultrafast gradient encoding