title: Colorectal neuroendocrine neoplasms - management guidelines (recommended by the Polish Network of Neuroendocrine Tumours).
abstract: Neuroendocrine neoplasms of the large intestine account for 20% of all neuroendocrine neoplasms (NENs) and are most commonly found in the rectum. The rate of detection of colorectal NENs is increasing, and this tendency will continue due to the widespread use of colonoscopy as a screening tool and the removal of all diagnosed lesions. This paper provides updated guidelines for the management of patients with colorectal NENs. Recent data on epidemiology, clinical characteristics, biochemical, and pathomorphological diagnosis as well as useful imaging techniques are presented. We look in detail at novel methods of treatment including endoscopic and surgical management, pharmacological and radioisotope therapy. We summarise monitoring of the treatment.
authors.forename: Teresa
authors.initials: T
authors.lastname: Starzyńska
authors.forename: Andrzej
authors.initials: A
authors.lastname: Deptała
authors.forename: Leszek
authors.initials: L
authors.lastname: Królicki
authors.forename: Jolanta
authors.initials: J
authors.lastname: Kunikowska
authors.forename: Magdalena
authors.initials: M
authors.lastname: Londzin-Olesik
authors.forename: Anna
authors.initials: A
authors.lastname: Nasierowska-Guttmejer
authors.forename: Marek
authors.initials: M
authors.lastname: Ruchała
authors.forename: Janusz
authors.initials: J
authors.lastname: Strzelczyk
authors.forename: Andrzej
authors.initials: A
authors.lastname: Szawłowski
authors.forename: Wojciech
authors.initials: W
authors.lastname: Zgliczyński
authors.affiliation: Division of Endocrinology, Department of Pathophysiology and Endocrinology, Medical University of Silesia, Katowice, Poland. endoklin@sum.edu.pl.
authors.forename: Beata
authors.initials: B
authors.lastname: Kos-Kudła
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002983:Clinical Competence; D003110:Colonic Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D003131:Combined Modality Therapy / Q000379:methods; D032921:Consensus; D004704:Endocrinology / Q000592:standards; D016099:Endoscopy, Gastrointestinal / Q000379:methods; D006801:Humans; D008495:Medical Oncology / Q000592:standards; D009367:Neoplasm Staging; D018358:Neuroendocrine Tumors / Q000175:diagnosis* / Q000628:therapy*; D011044:Poland; D011785:Quality Assurance, Health Care / Q000592:standards*