title: Prototheca wickerhamii algaemia presenting as cholestatic hepatitis in a patient with systemic lupus erythematosus: A case report and literature review.
abstract: Human protothecal infection is uncommon and could be localized or systemic disease. Disseminated Prototheca algaemia tends to occur in immunocompromised patients (solid organ transplants, hematological malignancies) with high mortality. Diagnosis could be missed or delayed due to unusual clinical presentation and/or under-recognition of characteristic microscopic features of Prototheca species. Combined approach that includes removal of source of infection and intravenous amphotericin B provides the best chance of cure.
authors.affiliation: Division of Infectious Diseases, University of Alabama at Birmingham, THT 229, 1530 3rd Avenue South, Birmingham, AL 35294-0006, USA.
authors.forename: Zaw
authors.initials: Z
authors.lastname: Min
authors.affiliation: Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham, 619 19th Street South, Birmingham, AL 35249-7331, USA.
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Moser
authors.affiliation: Division of Infectious Diseases, University of Alabama at Birmingham, THT 229, 1530 3rd Avenue South, Birmingham, AL 35294-0006, USA.
authors.forename: Peter G
authors.initials: PG
authors.lastname: Pappas
keywords: Algaemia; Cholestatic hepatitis; Prototheca spp; Systemic lupus erythematosus