title: Patient-prosthesis mismatch in pregnancy.
abstract: BACKGROUND
  Patient-prosthesis mismatch is a known and severe complication after aortic valve repair in the general population. There is a paucity of literature regarding this condition in pregnancy.
  
  
  METHODS
  We present the clinical course of a pregnant woman with severe patient-prosthesis mismatch after aortic valve replacement. After extensive workup, the patient underwent aortic valve replacement, enlargement of the aortic root, and placement of a larger prosthetic valve at 21 weeks of gestation. Her postoperative course was complicated by fetal death.
  
  
  CONCLUSIONS
  Cardiopulmonary bypass and aortic valve replacement present a multitude of risks to maternal and fetal health. The obstetrician managing pregnant women with prosthetic heart valves should be aware of the complications that may arise, including patient-prosthesis mismatch.
authors.affiliation: Department of Obstetrics & Gynecology, University of California Irvine Medical Center, Orange, and Miller Children's Hospital-Long Beach Memorial Medical Center, Long Beach, California.
authors.forename: Robert C
authors.initials: RC
authors.lastname: Johnston
authors.forename: Morgan L
authors.initials: ML
authors.lastname: Swank
authors.forename: Vineet K
authors.initials: VK
authors.lastname: Shrivastava
authors.forename: Afshan B
authors.initials: AB
authors.lastname: Hameed
mesh_terms: D000328:Adult; D001021:Aortic Valve / Q000637:transplantation; D005260:Female; D005313:Fetal Death; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D011183:Postoperative Complications / Q000209:etiology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D011475:Prosthesis Failure / Q000209:etiology*; D012086:Reoperation