title: Cadmium bioaccumulation in Mediterranean spider crab (Maya squinado): human consumption and health implications for exposure in Italian population.
abstract: Cd bioaccumulation pattern was investigated in Mediterranean spider crab (Maya squinado, Herbst, 1788) collected from the northern Adriatic Sea. Specimens were caught in the framework of a monitoring plan in order to quantify the Cd distribution into different organs and tissues of crab. For this purpose, Cd level was studied in appendages, cephalothorax, abdomen as well as gonads. Cd concentrations were found largely below the Maximum Level (ML) established at the European Union (EU) level for muscle from crab appendages (found mean 0.011 mg kg(-1)) and approximately amounted to 2% of the EU ML (0.50 mg kg(-1)). The higher Cd concentrations were found in organs and tissues included in crab body such as abdomen, chephalotorax and gonads with respect to appendages. Chephalotorax showed the highest metal concentration (mean value of 1.19 mg kg(-1)). The possible differences in Cd bioaccumulation rate among crab organs and tissues were also investigated applying a parametric linear regression. A major Cd bioaccumulation rate was revealed in chephalotorax with respect to other analyzed organs and tissues. Furthermore, the evaluation of health risk related to human consumption of the Mediterranean spider crab has been studied for median of total population, median and 95th percentile of consumers of Italy. The observed results highlighted that the consumption of organs and tissues included in crab body such as abdomen, gonads and, in particular, chephalotorax substantially increased the Cd intake reaching also alarming Estimated Weekly Intake (EWI) values especially for median and 95th percentile of Italian consumers.
authors.affiliation: Istituto Zooprofilattico Sperimentale delle Venezie, viale dell'Università 10, Legnaro, Padova, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Angeletti
authors.affiliation: Istituto Zooprofilattico Sperimentale delle Venezie, viale dell'Università 10, Legnaro, Padova, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Binato
authors.affiliation: National Reference Laboratory for Heavy Metals in Food, Department of Food Safety and Veterinary Public Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Guidotti
authors.affiliation: National Reference Laboratory for Heavy Metals in Food, Department of Food Safety and Veterinary Public Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Morelli
authors.affiliation: National Reference Laboratory for Heavy Metals in Food, Department of Food Safety and Veterinary Public Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
authors.forename: Augusto Alberto
authors.initials: AA
authors.lastname: Pastorelli
authors.affiliation: National Reference Laboratory for Heavy Metals in Food, Department of Food Safety and Veterinary Public Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Sagratella
authors.affiliation: National Reference Laboratory for Heavy Metals in Food, Department of Food Safety and Veterinary Public Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy. Electronic address: silvia.ciardullo@iss.it.
authors.forename: Silvia
authors.initials: S
authors.lastname: Ciardullo
authors.affiliation: National Reference Laboratory for Heavy Metals in Food, Department of Food Safety and Veterinary Public Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Stacchini
mesh_terms: D000818:Animals; D003386:Brachyura / Q000378:metabolism*; D002104:Cadmium / Q000378:metabolism* / Q000633:toxicity*; D004435:Eating; D004781:Environmental Exposure / Q000009:adverse effects*; D004785:Environmental Pollutants / Q000378:metabolism / Q000633:toxicity; D006262:Health; D006801:Humans; D007558:Italy; D012758:Shellfish / Q000032:analysis*
chemical_list: D004785:Environmental Pollutants; D002104:Cadmium
keywords: Bioaccumulation; Cadmium; Mediterranean spider crab; Tolerable weekly intake