title: Multiple antigenic peptide (MAP): a synthetic peptide dendrimer for diagnostic, antiviral and vaccine strategies for emerging and re-emerging viral diseases.
abstract: The peptide dendrimer provides novel strategies for various biological applications. Assembling of peptide in macromolecular structure is expected to give rational models as drugs, their delivery and diagnostic reagents. Improved understanding of virus structure and their molecular interactions with ligands have paved the way for treatment and control of emerging and re-emerging viral diseases. This review presents a brief account of a synthetic peptide dendrimer used for diagnostic, therapeutic and prophylactic applications. The designs comprise of multiple antigenic peptides which are being used as alternate synthetic antigens for different viruses.
authors.affiliation: Central Instrumentation Facility (Bio-engineering), Division Veterinary Biotechnology, Indian Veterinary Research Institute, Izatnagar, 243 122 UP India.
authors.forename: Vinay Ganeshrao
authors.initials: VG
authors.lastname: Joshi
authors.affiliation: Central Instrumentation Facility (Bio-engineering), Division Veterinary Biotechnology, Indian Veterinary Research Institute, Izatnagar, 243 122 UP India.
authors.forename: Vikas D
authors.initials: VD
authors.lastname: Dighe
authors.affiliation: Central Instrumentation Facility (Bio-engineering), Division Veterinary Biotechnology, Indian Veterinary Research Institute, Izatnagar, 243 122 UP India.
authors.forename: Dimpal
authors.initials: D
authors.lastname: Thakuria
authors.affiliation: Central Instrumentation Facility, Standardization Division, Indian Veterinary Research Institute, Izatnagar, 243 122 UP India.
authors.forename: Yashpal Singh
authors.initials: YS
authors.lastname: Malik
authors.affiliation: Central Instrumentation Facility (Bio-engineering), Division Veterinary Biotechnology, Indian Veterinary Research Institute, Izatnagar, 243 122 UP India.
authors.forename: Satish
authors.initials: S
authors.lastname: Kumar
keywords: Antiviral; Biosensor; Diagnostics; Multiple antigenic peptides; Peptide dendrimers; Synthetic peptide