title: [Combination of bone marrow concentrate and PGA scaffolds enhancing bone marrow stimulation in the repair of rabbit articular cartilage].
abstract: OBJECTIVE
  To observe the effects of bone marrow concentrate (BMC)-PGA scaffolds for bone marrow stimulation enhancement and repairing rabbit articular cartilage.
  
  
  METHODS
  A rabbit model of articular cartilage defect was established for BMC-PGA stent implantation. After 8 weeks, the experimental animals were sacrificed. And the methods of hematoxylin and eosin stain, toluidine blue stain and immunohistochemistry were used to evaluate the effects of bone marrow stimulation enhancement and rabbit cartilage defect repairing.
  
  
  RESULTS
  Visible new cartilage formation was evident after implantation. As compared with other groups, the repairing effect was better.
  
  
  CONCLUSIONS
  The implantation of BMC-PGA scaffolds is both simple and effective in the repair of articular cartilage.
authors.affiliation: Department of Orthopedics, First Municipal People's Hospital, Nanjing Medical University, Huai'an 223300, China.
authors.forename: Shou-guo
authors.initials: SG
authors.lastname: Wang
authors.affiliation: Department of Orthopedics, First Municipal People's Hospital, Nanjing Medical University, Huai'an 223300, China.
authors.forename: Hao-dong
authors.initials: HD
authors.lastname: Fei
authors.affiliation: Department of Orthopedics, First Municipal People's Hospital, Nanjing Medical University, Huai'an 223300, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Ji
authors.affiliation: Department of Orthopedics, First Municipal People's Hospital, Nanjing Medical University, Huai'an 223300, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Xie
authors.affiliation: Department of Orthopedics, First Municipal People's Hospital, Nanjing Medical University, Huai'an 223300, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Li
authors.affiliation: Department of Orthopedics, First Municipal People's Hospital, Nanjing Medical University, Huai'an 223300, China.
authors.forename: Ji-wei
authors.initials: JW
authors.lastname: Tian
authors.affiliation: Department of Orthopedics, Shanghai First People's Hospital, Shanghai Jiaotong University School of Medical, Email: sawboneszhao@163.com.
authors.forename: Qing-hua
authors.initials: QH
authors.lastname: Zhao
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000187:drug effects*; D016026:Bone Marrow Transplantation; D002358:Cartilage, Articular; D002478:Cells, Cultured; D020219:Chondrogenesis; D008297:Male; D011817:Rabbits; D054457:Tissue Scaffolds