title: [Chronic renal disease in patients with systemic scleroderma: the prevalence and associated factors].
abstract: The aim of this work was to study the incidence of chronic renal disease (CRD) in 100 patients with systemic scleroderma (SS) who underwent general clinical and laboratory examination; glomerular filtration rate (GFR) was calculated. Statistica 8.0 and Excel 2007 programs were used to treat the results. 88% of the patients with SS had CRD, 80% showed lowered GFR and 81% suffered hypostenuria and/or proteinuria. GFR correlated with the presence of cardiac lesions and pulmonary hypertension, Valentini activity index, renal vessel resistance, concomitant renal pathology, arterial hypertension and/or CHD. Also, reduced GFR associated with myocardiofibrosis, atrioventricular valve incompetence, age and concomitant diseases (AH, DM, CRD, renal and urinary tract pathology).
authors.forename: A P
authors.initials: AP
authors.lastname: Rebrov
authors.forename: I Z
authors.initials: IZ
authors.lastname: Gaĭdukova
authors.forename: D A
authors.initials: DA
authors.lastname: Patrikeeva
mesh_terms: D000328:Adult; D000367:Age Factors; D009202:Cardiomyopathies / Q000453:epidemiology / Q000209:etiology; D002908:Chronic Disease; D015897:Comorbidity; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000453:epidemiology / Q000209:etiology; D015994:Incidence; D007674:Kidney Diseases / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D008297:Male; D008875:Middle Aged; D015166:Monitoring, Immunologic; D062072:Patient Acuity; D012189:Retrospective Studies; D012307:Risk Factors; D012595:Scleroderma, Systemic / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D012737:Sex Factors