title: Indeterminate QuantiFERON-TB gold in-tube assay results in children: possible association with procedural specimen collection.
abstract: Fifty-six of 182 (31%) children had indeterminate QuantiFERON assays. Indeterminate assays were associated with inpatient status [odds ratios (OR): 11.7, 95% confidence interval 3.9-34.9], but not with age, gender or medical comorbidities. This indicates that indeterminates may be due to specimen handling, and proper procedural training may be necessary to decrease indeterminate QuantiFERON results.
authors.affiliation: From the *University of Texas-Houston School of Public Health; †Department of Pediatrics, Baylor College of Medicine; and ‡Department of Pathology and Genomic Medicine, The Methodist Hospital Research Institute, Houston, TX.
authors.forename: Duc-Hieu P
authors.initials: DH
authors.lastname: Bui
authors.forename: Andrea T
authors.initials: AT
authors.lastname: Cruz
authors.forename: Edward A
authors.initials: EA
authors.lastname: Graviss
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D059425:Interferon-gamma Release Tests / Q000379:methods* / Q000592:standards*; D008297:Male; D015999:Multivariate Analysis; D016017:Odds Ratio; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000175:diagnosis*