title: Effect of arteriovenous hemodialysis shunt location on cardiac events in patients having coronary artery bypass graft using an internal thoracic artery.
abstract: The possibility of developing coronary steal in patients having coronary artery bypass graft (CABG) using internal thoracic artery (ITA) and ipsilateral upper extremity arteriovenous (AV) hemodialysis shunt has been reported. The impact of this phenomenon on clinical outcomes is uncertain. The aim of this study was to investigate an association between the AV dialysis shunt location regarding the side of the ITA CABG and clinical outcomes. This retrospective cohort study included chronic hemodialysis patients having ITA CABG and upper extremity AV shunt. The patients were divided into two groups: those with ipsilateral and those with contralateral location of ITA CABG and AV shunt. The outcomes were: death from any cause, cardiac death and a first cardiac event. In a group of 112 chronic hemodialysis patients having CABG, 32 had an ipsilateral and 25 had a contralateral location of ITA CABG and an upper extremity AV shunt. Significantly more cardiac events occurred in the group with an ipsilateral compared to a contralateral location of ITA CABGs and dialysis AV shunts (hazard ratio, 2.16 [95% CI, 1.11 to 4.19], P = 0.023). There was no difference between the groups in the all cause mortality risk (hazard ratio, 1.005 [95% CI, 0.43 to 2.37], P = 0.990) or the risk of cardiac death (hazard ratio, 2.43 [95% CI, 0.64 to 9.17], P = 0.191). The ipsilateral location of a CABG with the use of ITA and upper extremity AV hemodialysis shunt may be associated with increased risk of cardiac events.
authors.affiliation: Nephrology Department, Internal Medicine Department, Vascular Surgery Department, Assaf Harofeh Medical Center, Zerifin, Israel; Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
authors.forename: Leonid
authors.initials: L
authors.lastname: Feldman
authors.forename: Inna
authors.initials: I
authors.lastname: Tkacheva
authors.forename: Shai
authors.initials: S
authors.lastname: Efrati
authors.forename: Igor
authors.initials: I
authors.lastname: Rabin
authors.forename: Ilia
authors.initials: I
authors.lastname: Beberashvili
authors.forename: Oleg
authors.initials: O
authors.lastname: Gorelik
authors.forename: Zhan
authors.initials: Z
authors.lastname: Averbukh
authors.forename: Michal
authors.initials: M
authors.lastname: Shani
mesh_terms: D000368:Aged; D001166:Arteriovenous Shunt, Surgical / Q000379:methods*; D015331:Cohort Studies; D001026:Coronary Artery Bypass / Q000379:methods*; D058686:Coronary-Subclavian Steal Syndrome / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008323:Mammary Arteries / Q000637:transplantation*; D008875:Middle Aged; D006435:Renal Dialysis; D012189:Retrospective Studies; D034941:Upper Extremity / Q000098:blood supply
keywords: Coronary artery disease; Dialysis fistula; Dialysis graft; Hemodialysis; Vascular access