title: Resident-performed selective laser trabeculoplasty in patients with open-angle glaucoma.
abstract: IMPORTANCE To our knowledge, this is the first study to investigate effectiveness and complication rates of resident-performed selective laser trabeculoplasty (SLT). OBJECTIVES To evaluate the effectiveness and complications of SLT performed by resident ophthalmologists and to identify predictors for success. DESIGN, SETTING, AND PARTICIPANTS Retrospective case series of 81 patients with open-angle glaucoma undergoing 110 SLT procedures from November 17, 2009, through December 16, 2011, at the San Francisco Veterans Affairs Medical Center. INTERVENTION Resident-performed SLT. MAIN OUTCOMES AND MEASURES Intraocular pressure (IOP) reduction. Secondary outcomes included change in eyedrop medications, complication rates, and predictors of SLT success defined as a 20% reduction in IOP. RESULTS The mean IOP at baseline, defined as the average IOP of the 2 appointments prior to the SLT procedure, was 18.7 mm Hg. The mean decrease in postoperative IOP compared with baseline was 2.2 mm Hg (12%; 95% CI, 5%-19%) at 12 months and 3.3 mm Hg (18%; 95% CI, 13%-23%), 2.8 mm Hg (15%; 95% CI, 10%-21%), and 3.6 mm Hg (19%; 95% CI, 11%-27%) at 3, 6, and 24 months, respectively (all P &lt; .001, linear mixed-effects regression). Success rates were 36% (95% CI, 27%-47%) at 12 months and 41% (95% CI, 31%-53%), 50% (95% CI, 40%-60%), and 39% (95% CI, 26%-53%) at 3, 6, and 24 months, respectively. The most common complication was a temporary IOP spike, with increases of at least 6 mm Hg occurring in 7% (95% CI, 4%-14%) of the population. The largest IOP spike was 11 mm Hg. Increased number of laser shots performed was not associated with better IOP control but was associated with a reduction in number of eyedrop medications (P = .02). Increased baseline IOP was associated with an odds ratio for success of 1.24 (95% CI, 1.08-1.44) at 3 months, 1.20 (95% CI, 1.05-1.37) at 6 months, and 1.31 (95% CI, 1.13-1.53) at 12 months of follow-up (P = .003, P = .006, and P &lt; .001, respectively, logistic regression). In a multivariate analysis, baseline IOP remained the greatest predictor of effectiveness. CONCLUSIONS AND RELEVANCE Resident-performed SLT obtains outcomes similar to the IOP reduction reported in the literature for attending-performed SLT with low levels of complications. Increasing the number of shots in a treatment session may lead to less long-term need for eyedrop medications. In this patient group, higher baseline IOP was the strongest predictor of treatment effectiveness.
authors.affiliation: Department of Ophthalmology, Oregon Health and Science University, Portland2Department of Ophthalmology, University of California, San Francisco.
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Greninger
authors.affiliation: Department of Ophthalmology, University of California, San Francisco.
authors.forename: Eugene A
authors.initials: EA
authors.lastname: Lowry
authors.affiliation: Department of Ophthalmology, University of California, San Francisco3Division of Preventive Medicine and Public Health, Department of Epidemiology and Biostatistics, University of California, San Francisco4Francis I. Proctor Foundation, University of Cali.
authors.forename: Travis C
authors.initials: TC
authors.lastname: Porco
authors.affiliation: Department of Ophthalmology, University of California, San Francisco4Francis I. Proctor Foundation, University of California, San Francisco5Department of Ophthalmology, San Francisco VA Medical Center, San Francisco, California.
authors.forename: Ayman
authors.initials: A
authors.lastname: Naseri
authors.affiliation: Department of Ophthalmology, University of California, San Francisco5Department of Ophthalmology, San Francisco VA Medical Center, San Francisco, California.
authors.forename: Robert L
authors.initials: RL
authors.lastname: Stamper
authors.affiliation: Department of Ophthalmology, University of California, San Francisco4Francis I. Proctor Foundation, University of California, San Francisco5Department of Ophthalmology, San Francisco VA Medical Center, San Francisco, California.
authors.forename: Ying
authors.initials: Y
authors.lastname: Han
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002983:Clinical Competence; D004503:Education, Medical, Graduate / Q000592:standards*; D004521:Educational Measurement; D005260:Female; D005902:Glaucoma, Open-Angle / Q000601:surgery*; D006801:Humans; D007396:Internship and Residency; D007429:Intraocular Pressure / Q000502:physiology; D007431:Intraoperative Complications; D053685:Laser Therapy; D008297:Male; D009885:Ophthalmology / Q000193:education*; D011183:Postoperative Complications; D012189:Retrospective Studies; D014065:Tonometry, Ocular; D014129:Trabecular Meshwork / Q000601:surgery; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents