title: [Prognostic effect of posterior cerebral artery laterality on middle cerebral artery occlusion].
abstract: OBJECTIVE
  To explore the prognostic value of posterior cerebral artery (PCA) laterality in patients with symptomatic middle cerebral artery (MCA) occlusion on standard medical therapy.
  
  
  METHODS
  Forty consecutive patients with first onset isolated atherosclerotic occlusion in M1 segment of MCA received medication from June 2009 to March 2013. All patients underwent magnetic resonance angiography (MRA) for assessment of PCA laterality. Clinical data and modified Rankin Scale (mRS) at 3 months were compared between PCA positive and negative patients. Retrospective analysis was performed on their clinical and imaging data.
  
  
  RESULTS
  Among them, 20 patients (50%) showed PCA laterality on MRA and 32 patients (80%) completed a 3-month follow-up. No significant difference existed between PCA laterality positive and negative groups in a favorable outcome of mRS = 0-1 at 3 months (P = 0.433).
  
  
  CONCLUSIONS
  The presence of PCA laterality showed no prognostic effect on patients with symptomatic MCA occlusion on standard medical therapy.
authors.affiliation: Department of Neurology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210002, China.
authors.forename: Xiang-liang
authors.initials: XL
authors.lastname: Chen
authors.forename: Yun-yun
authors.initials: YY
authors.lastname: Xiong
authors.forename: Yong-kun
authors.initials: YK
authors.lastname: Li
authors.affiliation: Email: mmmxkx@gmail.com.
authors.forename: Min-min
authors.initials: MM
authors.lastname: Ma
authors.forename: Xin-feng
authors.initials: XF
authors.lastname: Liu
mesh_terms: D000328:Adult; D005260:Female; D007839:Functional Laterality; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000175:diagnosis* / Q000473:pathology*; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D020769:Posterior Cerebral Artery / Q000473:pathology*; D011379:Prognosis; D012189:Retrospective Studies