title: Using Spectralis and Stratus optical coherence tomography devices to analyze the retinal nerve fiber layer in patients with open-angle glaucoma - preliminary report.
abstract: BACKGROUND
  During the study at the Ophthalmology Clinic of Wroclaw Medical University retinal nerve fiber layer (RNFL) thickness was examined in 35 patients with open-angle glaucoma.
  
  
  OBJECTIVE
  The aim of the study was to analyse RNFL thickness measurements by 2 different optical coherence tomography (OCT) devices.
  
  
  METHODS
  The study group consisted of 35 patients with open-angle glaucoma (aged 48-76 years, including 20 women and 15 men - 70 eyes) with intraocular pressure below 19 mm Hg, treated pharmacologically. The subjects were examined using a Stratus Time Domain OCT (TD-OCT), produced by Zeiss, and a Spectralis Spectral Domain OCT (SD-OCT), manufactured by Heidelberg Engineering. The OCT examination was carried out with both devices on the same day in random order.
  
  
  RESULTS
  The study shows that the results obtained using the 2 devices are correlated, although the average measurements of RNFL thickness were lower for the Spectralis OCT in comparison with those taken by the Stratus OCT. The strongest correlation was found for the temporal and nasal quadrants.
  
  
  CONCLUSIONS
  The study results using the Spectralis OCT and Stratus OCT are similar, but not identical, so follow-up tests should be performed on the same apparatus as in the initial testing. Considering the new generation of apparatus and the more precise measurement algorithm, the results obtained using the Spectralis SD-OCT seem more accurate.
authors.affiliation: Department and Clinic Ophthalmology, Wroclaw Medical University, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Mulak
authors.forename: Anna
authors.initials: A
authors.lastname: Cicha
authors.forename: Kamil
authors.initials: K
authors.lastname: Kaczorowski
authors.forename: Bartłomiej
authors.initials: B
authors.lastname: Markuszewski
authors.forename: Marta
authors.initials: M
authors.lastname: Misiuk-Hojło
mesh_terms: D000368:Aged; D005260:Female; D005902:Glaucoma, Open-Angle / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D012160:Retina / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000295:instrumentation*