title: A new itch to scratch for TSLP.
abstract: Atopic dermatitis (AD) is characterized by allergic inflammation and itch. Thymic stromal lymphopoietin (TSLP) is a pro-allergic cytokine implicated in AD. A paper in Cell transforms the understanding of the functional repertoire of TSLP in general and in AD in particular showing that TSLP can directly stimulate sensory neurons and provoke itch.
authors.affiliation: Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, IN 46202, USA.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Turner
authors.affiliation: Department of Pediatrics and Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Electronic address: zhoub@iu.edu.
authors.forename: Baohua
authors.initials: B
authors.lastname: Zhou
mesh_terms: D000818:Animals; D016207:Cytokines / Q000378:metabolism*; D003876:Dermatitis, Atopic / Q000473:pathology*; D006801:Humans; D015398:Signal Transduction
chemical_list: D016207:Cytokines