title: The Utility of the Platelet-Lymphocyte Ratio for Predicting No Reflow in Patients With ST-Segment Elevation Myocardial Infarction.
abstract: The aim of the study was to evaluate the utility of the preprocedural platelet-lymphocyte ratio (PLR) for predicting no reflow in patients undergoing primary percutaneous intervention (PCI) for the treatment of ST-segment elevation myocardial infarction. The thrombolysis in myocardial infarction (TIMI) flow grades of 287 patients treated with primary PCI were assessed retrospectively. Patients were divided into 3 tertiles based upon preprocedural PLR. Pre- and postprocedural TIMI flow grades were evaluated. No reflow developed in 6, 14, and 43 patients in the lower, middle, and higher tertiles, respectively (P < .001). After multivariate analysis, PLR remained a significant predictor of no reflow together with neutrophil-lymphocyte ratio (NLR). A cutoff value of 160 for PLR and 5.9 for NLR predicted no reflow with sensitivities and specificities of 75% and 71% and 74% and 70%, respectively. In conclusion, high preprocedural PLR and NLR levels are significant and independent predictors of no reflow in patients undergoing primary PCI.
authors.affiliation: Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey drakadiryildiz@gmail.com.
authors.forename: Abdulkadir
authors.initials: A
authors.lastname: Yildiz
authors.affiliation: Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Yuksel
authors.affiliation: Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Oylumlu
authors.affiliation: Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey.
authors.forename: Nihat
authors.initials: N
authors.lastname: Polat
authors.affiliation: Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Akyuz
authors.affiliation: Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey.
authors.forename: Halit
authors.initials: H
authors.lastname: Acet
authors.affiliation: Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey.
authors.forename: Mesut
authors.initials: M
authors.lastname: Aydin
authors.affiliation: Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey.
authors.forename: Mehmet Siddik
authors.initials: MS
authors.lastname: Ülgen
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D054318:No-Reflow Phenomenon / Q000097:blood* / Q000601:surgery*; D062645:Percutaneous Coronary Intervention; D010976:Platelet Count; D012189:Retrospective Studies
keywords: acute ST-segment elevation myocardial infarction; no reflow; platelet to lymphocyte ratio; primary percutaneous coronary intervention