title: Bilateral tubulocystic renal cell carcinomas in diabetic end-stage renal disease: first case report with cytogenetic and ultrastructural studies.
abstract: Tubulocystic renal cell carcinoma (TC-RCC) is a rare renal tumor composed of well-differentiated tubules and cysts lined by neoplastic cells with eosinophilic cytoplasm and prominent nucleoli. The origin of the tumor cells is still controversial. TC-RCC typically arises unilaterally. Involvement of both kidneys by multifocal TC-RCC has not been reported. In this study we report the first case of bilateral and multifocal TC-RCC. Immunohistochemical, cytogenetic and ultrastructural studies suggest TC-RCC is closely related to papillary RCC.
authors.affiliation: Departments of Pathology, New York Harbor VA Medical Center, New York University School of Medicine , NY.
authors.forename: Max Xiangtian
authors.initials: MX
authors.lastname: Kong
authors.affiliation: Departments of Pathology, New York Harbor VA Medical Center, New York University School of Medicine , NY.
authors.forename: Christopher
authors.initials: C
authors.lastname: Hale
authors.affiliation: Departments of Pathology, New York Harbor VA Medical Center, New York University School of Medicine , NY.
authors.forename: Antonio
authors.initials: A
authors.lastname: Subietas-Mayol
authors.affiliation: Departments of Pathology, New York Harbor VA Medical Center, New York University School of Medicine , NY.
authors.forename: Peng
authors.initials: P
authors.lastname: Lee
authors.affiliation: Departments of Pathology, New York Harbor VA Medical Center, New York University School of Medicine , NY.
authors.forename: Nicholas D
authors.initials: ND
authors.lastname: Cassai
authors.affiliation: Departments of Pathology, New York Harbor VA Medical Center, New York University School of Medicine , NY.
authors.forename: Gerald
authors.initials: G
authors.lastname: McRae
authors.affiliation: Departments of Medicine, New York Harbor VA Medical Center, New York University School of Medicine , NY.
authors.forename: David S
authors.initials: DS
authors.lastname: Goldfarb
authors.affiliation: Departments of Pathology, New York Harbor VA Medical Center, New York University School of Medicine , NY ; Department of Anatomic Pathology, Cleveland Clinic , Cleveland, OH, USA.
authors.forename: Ming
authors.initials: M
authors.lastname: Zhou
authors.affiliation: Departments of Pathology, New York Harbor VA Medical Center, New York University School of Medicine , NY.
authors.forename: Rosemary
authors.initials: R
authors.lastname: Wieczorek
keywords: cytogenetics; immunohistochemistry; renal cell carcinoma; tubulocystic carcinoma