title: Anti-obesity effects of traditional and standardized meju in high-fat diet-induced obese C57BL/6J mice.
abstract: The aim of the study was to evaluate the anti-obesity effects of two types of meju in diet induced obese C57BL/6J mice. Animals were randomly divided into 4 dietary group (n = 10); normal diet, high fat diet with 30% soybean, high fat diet with 30% traditional meju, high fat diet with 30% standardized meju. After 16 weeks, after animals were sacrificed. It was observed that the high fat diet with 30% traditional meju and high fat diet with 30% standardized meju significantly reduced body weight gain, epididymal fat weight, serum triglyceride along with serum insulin and leptin levels compared to the high fat diet with 30% soybean. And also, the expression levels of hepatic lipid anabolic genes were significantly decreased in the high fat diet with 30% traditional meju and high fat diet with 30% standardized meju compared to the high fat diet with 30% soybean. In conclusion, the assessment of all the obesity markers strongly advocate the anti-obesity effect of traditional as well as standardized meju in diet induce obesity conditions.
authors.affiliation: Department of Food Science and Human Nutrition, and Research Institute of Humans Ecology, Chonbuk National University, 567 Baekje-daero, deokjin-gu, Jeonju-si, Jeollabuk-do 561-756, Republic of Korea.
authors.forename: Cho-Rong
authors.initials: CR
authors.lastname: Bae
authors.affiliation: Korea Food Research Division, Korea Food Research Institute, Sungnam, Republic of Korea.
authors.forename: Dae-Young
authors.initials: DY
authors.lastname: Kwon
authors.affiliation: Department of Food Science and Human Nutrition, and Research Institute of Humans Ecology, Chonbuk National University, 567 Baekje-daero, deokjin-gu, Jeonju-si, Jeollabuk-do 561-756, Republic of Korea.
authors.forename: Youn-Soo
authors.initials: YS
authors.lastname: Cha
keywords: C57BL/6J mice; anti-obesity; high fat diet; lipid metabolism; meju