title: Diagnostic accuracy of leukocytosis in prediction of acute appendicitis.
abstract: An analytical study was conducted to find out the diagnostic accuracy of leukocytosis in predicting acute appendicitis in patients undergoing emergency appendicectomy. The degree of inflammation of the resected specimens was grossly assessed and graded into acute inflammation, acute inflammation with complications (such as gangrene, perforation, abscess) and un-inflamed appendix. The operative findings were correlated with leukocyte counts using 2 x 2 table. Out of 233 appendicectomies, with exclusion of the negative appendicectomies (17.59%, n = 41), there were 67.38% patients (n = 157) with elevated leukocyte count. The overall sensitivity, specificity, positive predictive value and negative predictive value of elevated leukocyte counts for inflamed appendix were 91.81%, 43.55%, 81.77% and 65.85% respectively.
authors.affiliation: Department of General Surgery, Pakistan Institute of Medical Sciences (PIMS), Islamabad.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Saaiq
authors.affiliation: Department of General Surgery, Pakistan Institute of Medical Sciences (PIMS), Islamabad.
authors.lastname: Niaz-Ud-Din
authors.affiliation: Department of General Surgery, Pakistan Institute of Medical Sciences (PIMS), Islamabad.
authors.forename: Ana
authors.initials: A
authors.lastname: Jalil
authors.affiliation: Department of General Surgery, Pakistan Institute of Medical Sciences (PIMS), Islamabad.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Zubair
authors.affiliation: Department of General Surgery, Pakistan Institute of Medical Sciences (PIMS), Islamabad.
authors.forename: Syed Aslam
authors.initials: SA
authors.lastname: Shah
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D001062:Appendectomy; D001064:Appendicitis / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D002097:C-Reactive Protein / Q000032:analysis; D002648:Child; D005260:Female; D021501:Flank Pain / Q000209:etiology; D006801:Humans; D007249:Inflammation / Q000150:complications* / Q000601:surgery; D007958:Leukocyte Count; D007964:Leukocytosis / Q000097:blood / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
chemical_list: D002097:C-Reactive Protein