title: Primary scalp angiosarcoma with metastasis to the liver in an orthotopic liver transplant patient.
abstract: Angiosarcoma is a rare malignant neoplasm of vascular endothelial cells. A majority are primarily in the skin. Angiosarcoma of the head and neck is the most common form, but only constitutes 0.1% of all head and neck malignancies. We present an extraordinary case of a 71-year-old man 6 months status postorthotopic liver transplant secondary to end-stage liver disease from cryptogenic cirrhosis, who presented to the liver clinic with a rapidly growing scalp tumor and hypodense lesions within the liver. Further work-up and biopsies confirmed the first documented case of primary scalp angiosarcoma with metastasis to the liver in an orthotopic liver transplant patient.
authors.affiliation: Kansas Medical Center, Department of Medicine, Division of Dermatology, Kansas City, Kansas; the University of Missouri-Kansas City School of Medicine, Kansas City, Missouri; the University of Kansas Medical Center, Department of Medicine, Division of Hepatology; and the University of Kansas Medical Center, Department of Pathology and Laboratory Medicine, Kansas City, Kansas, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Blackmon
authors.forename: Anand
authors.initials: A
authors.lastname: Rajpara
authors.forename: Vikas
authors.initials: V
authors.lastname: Patel
authors.forename: Richard
authors.initials: R
authors.lastname: Gilroy
authors.forename: Daniel
authors.initials: D
authors.lastname: Aires
authors.forename: Garth
authors.initials: G
authors.lastname: Fraga
mesh_terms: D000368:Aged; D001706:Biopsy; D058625:End Stage Liver Disease / Q000175:diagnosis / Q000601:surgery*; D017809:Fatal Outcome; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006394:Hemangiosarcoma / Q000556:secondary*; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary*; D016031:Liver Transplantation; D008279:Magnetic Resonance Imaging; D008297:Male; D049268:Positron-Emission Tomography; D012535:Scalp / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*