title: Acute exposure to a 2 mT static magnetic field affects ionic homeostasis of in vitro grown porcine granulosa cells.
abstract: In this work, we provided direct evidence for the first time that exposure to a static magnetic field (SMF) of low intensity (2 mT) is immediately followed by a reversible cell membrane depolarization wave (of about 1 min) that causes the rise of intracellular calcium and the decrease of mitochondrial activity of vital granulosa cells. These effects are likely due to the increase in Na(+) and Ca(2+) cell membrane permeability.
authors.affiliation: Department of Biomedical Comparative Sciences, University of Teramo, Teramo, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Bernabò
authors.forename: Ilaria
authors.initials: I
authors.lastname: Saponaro
authors.forename: Enzo
authors.initials: E
authors.lastname: Tettamanti
authors.forename: Mauro
authors.initials: M
authors.lastname: Mattioli
authors.forename: Barbara
authors.initials: B
authors.lastname: Barboni
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000378:metabolism; D002462:Cell Membrane / Q000502:physiology; D002463:Cell Membrane Permeability; D002478:Cells, Cultured; D005110:Extracellular Space / Q000378:metabolism; D005260:Female; D006107:Granulosa Cells / Q000502:physiology*; D006706:Homeostasis; D042541:Intracellular Space / Q000378:metabolism; D060526:Magnetic Fields; D008564:Membrane Potentials; D008928:Mitochondria / Q000502:physiology; D012964:Sodium / Q000378:metabolism*; D013552:Swine; D061566:Voltage-Gated Sodium Channels / Q000378:metabolism
chemical_list: D015220:Calcium Channels; D061566:Voltage-Gated Sodium Channels; D012964:Sodium; D002118:Calcium
keywords: confocal microscopy; granulosa cells; ionic homeostasis; static magnetic field; swine