title: Neonatal stroke: a review of the current evidence on epidemiology, pathogenesis, diagnostics and therapeutic options.
abstract: Neonatal stroke, including perinatal arterial ischaemic stroke and cerebral sinovenous thrombosis, remains a serious problem in the neonate. This article reviews the current evidence on epidemiology, pathogenesis, diagnostics and therapeutic options.
  
  
  CONCLUSIONS
  Although our understanding of the underlying mechanisms and possible risk factors has improved, little progress has been made towards therapeutic options. Considering the high incidence of neurological sequelae, the need for therapeutic options is high and should be the focus of future research.
authors.affiliation: Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.
authors.forename: N E
authors.initials: NE
authors.lastname: van der Aa
authors.forename: M J N L
authors.initials: MJ
authors.lastname: Benders
authors.forename: F
authors.initials: F
authors.lastname: Groenendaal
authors.forename: L S
authors.initials: LS
authors.lastname: de Vries
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D020521:Stroke / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy
keywords: Cerebral sinovenous thrombosis; MRI; Neonatal stroke