title: [Use of misoprostol in gynaecology].
abstract: OBJECTIVE
  To assess the interest of misoprostol in gynaecology and particularly for cervical priming.
  
  
  METHODS
  Research in PubMed in English and French about misoprostol and its use in gynaecology.
  
  
  RESULTS
  We summarized the results of 3 meta-analyses, randomized controlled trials and literature review. Results show that misoprostol did not scientifically prove a benefit for cervical priming before hysteroscopy or before intra-uterine device (IUD). Results are the same with post-menopausal or nulliparous women. It did not lead either to lower the complications but increase adverse effects.
  
  
  CONCLUSIONS
  It is not indicated to use misoprostol for cervical priming in gynaecology.
authors.affiliation: Service de gynécologie-obstétrique, CHU de Bicêtre, 78, avenue du Général-Leclerc, 94276 Le Kremlin-Bicêtre, France. Electronic address: magali.lesavre@bct.aphp.fr.
authors.forename: M
authors.initials: M
authors.lastname: Lesavre
authors.affiliation: Service de gynécologie-obstétrique, CHU de Bicêtre, 78, avenue du Général-Leclerc, 94276 Le Kremlin-Bicêtre, France.
authors.forename: G
authors.initials: G
authors.lastname: Legendre
authors.affiliation: Service de gynécologie-obstétrique, CHU de Bicêtre, 78, avenue du Général-Leclerc, 94276 Le Kremlin-Bicêtre, France.
authors.forename: H
authors.initials: H
authors.lastname: Fernandez
mesh_terms: D020070:Cervical Ripening; D002584:Cervix Uteri / Q000187:drug effects*; D005260:Female; D006176:Gynecology / Q000379:methods*; D006801:Humans; D015907:Hysteroscopy / Q000379:methods; D007433:Intrauterine Device Expulsion; D016595:Misoprostol / Q000009:adverse effects / Q000627:therapeutic use*; D010298:Parity; D017698:Postmenopause; D011247:Pregnancy; D016032:Randomized Controlled Trials as Topic
chemical_list: D016595:Misoprostol
keywords: Cervical priming; DIU; Dilatation cervicale; Hysteroscopy; Hystéroscopie; IUD; Misoprostol