title: Rapid measurement of multidimensional 1H solid-state NMR spectra at ultra-fast MAS frequencies.
abstract: A novel method to realize rapid repetition of (1)H NMR experiments at ultra-fast MAS frequencies is demonstrated. The ultra-fast MAS at 110kHz slows the (1)H-(1)H spin diffusion, leading to variations of (1)H T1 relaxation times from atom to atom within a molecule. The different relaxation behavior is averaged by applying (1)H-(1)H recoupling during relaxation delay even at ultra-fast MAS, reducing the optimal relaxation delay to maximize the signal to noise ratio. The way to determine optimal relaxation delay for arbitrary relaxation curve is shown. The reduction of optimal relaxation delay by radio-frequency driven recoupling (RFDR) was demonstrated on powder samples of glycine and ethenzamide with one and multi-dimensional NMR measurements.
authors.affiliation: JEOL RESONANCE Inc., Musashino, Akishima, Tokyo 196-8558, Japan.
authors.forename: Yue Qi
authors.initials: YQ
authors.lastname: Ye
authors.affiliation: JEOL RESONANCE Inc., Musashino, Akishima, Tokyo 196-8558, Japan.
authors.forename: Michal
authors.initials: M
authors.lastname: Malon
authors.affiliation: Tectospin, Institut Lavoisier de Versailles, Université de Versailles, Saint-Quentin-en-Yvelines, 78035 Versailles Cedex, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Martineau
authors.affiliation: Tectospin, Institut Lavoisier de Versailles, Université de Versailles, Saint-Quentin-en-Yvelines, 78035 Versailles Cedex, France.
authors.forename: Francis
authors.initials: F
authors.lastname: Taulelle
authors.affiliation: JEOL RESONANCE Inc., Musashino, Akishima, Tokyo 196-8558, Japan. Electronic address: yunishiy@jeol.co.jp.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Nishiyama
mesh_terms: D000465:Algorithms; D000596:Amino Acids / Q000737:chemistry*; D004574:Electromagnetic Fields; D005998:Glycine / Q000032:analysis; D006639:Histidine / Q000032:analysis; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D059629:Signal-To-Noise Ratio
chemical_list: D000596:Amino Acids; D006639:Histidine; D005998:Glycine
keywords: 1H T1 relaxation; Relaxation delay; Solid-state NMR; Spin diffusion; Ultra-fast MAS