title: Single-crystalline hyperbranched nanostructure of iron hydroxyl phosphate Fe5(PO4)4(OH)3·2H2O for highly selective capture of phosphopeptides.
abstract: Single-crystalline hyperbranched nanostructures of iron hydroxyl phosphate Fe5(PO4)4(OH)3·2H2O (giniite) with orthorhombic phase were synthesized through a simple route. They have a well-defined dendrite fractal structure with a pronounced trunk and highly ordered branches. The toxicity test shows that the hyperbranched nanostructures have good biocompatibility and low toxicity level, which makes them have application potentials in life science. The study herein demonstrated that the obtained hyperbranched giniite nanostructures show highly selective capture of phosphopeptides and could be used as a kind of promising nanomaterial for the specific capture of phosphopeptides from complex tryptic digests with the detection of MALDI-TOF mass spectrometry.
authors.affiliation: Department of Materials Science and Engineering, Nanjing University, Nanjing 210093, P. R. China.
authors.forename: Qun
authors.initials: Q
authors.lastname: Chen
authors.affiliation: 1] Department of Materials Science and Engineering, Nanjing University, Nanjing 210093, P. R. China [2] State Key Laboratory of Coordination Chemistry, Coordination Chemistry Institute, Nanjing National Laboratory of Microstructures, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China.
authors.forename: Chengzhen
authors.initials: C
authors.lastname: Wei
authors.affiliation: Department of Materials Science and Engineering, Nanjing University, Nanjing 210093, P. R. China.
authors.forename: Yizhou
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: 1] Department of Materials Science and Engineering, Nanjing University, Nanjing 210093, P. R. China [2] State Key Laboratory of Coordination Chemistry, Coordination Chemistry Institute, Nanjing National Laboratory of Microstructures, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China.
authors.forename: Huan
authors.initials: H
authors.lastname: Pang
authors.affiliation: State Key Laboratory of Coordination Chemistry, Coordination Chemistry Institute, Nanjing National Laboratory of Microstructures, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China.
authors.forename: Qingyi
authors.initials: Q
authors.lastname: Lu
authors.affiliation: Department of Materials Science and Engineering, Nanjing University, Nanjing 210093, P. R. China.
authors.forename: Feng
authors.initials: F
authors.lastname: Gao
mesh_terms: D005290:Ferric Compounds / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D010748:Phosphopeptides / Q000737:chemistry*
chemical_list: D005290:Ferric Compounds; D010748:Phosphopeptides