title: Oral malignant acanthosis nigricans associated with endometrial adenocarcinoma.
abstract: We report a 59-year-old patient with malignant acanthosis nigricans associated with metastasis of endometrial carcinoma. The patient presented papillomatosis lesions that appeared to be benign on multiple skins of body folds, particularly on lips. The lesions in lips and axilla had histological characteristic appearances of acanthosis nigricans, while the masses in abdomen and pelvis were metastasis endometrial adenocarcinoma. The article highlights the importance of biopsy and histopathological diagnosis in presumed benign lesions and the role of doctors in screening for body internal tumors.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
authors.forename: Han-Wen
authors.initials: HW
authors.lastname: Chu
authors.affiliation: Hangzhou Stomatological Hospital, Hangzhou, China.
authors.forename: Jing-Min
authors.initials: JM
authors.lastname: Li
authors.affiliation: Department of Oral and Maxillofacial Surgery, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
authors.forename: Guan-Fu
authors.initials: GF
authors.lastname: Chen
authors.affiliation: Department of Oral Medicine, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
authors.forename: Jing-Yuan
authors.initials: JY
authors.lastname: Ma
mesh_terms: D000008:Abdominal Neoplasms / Q000556:secondary; D000052:Acanthosis Nigricans / Q000473:pathology*; D000230:Adenocarcinoma / Q000556:secondary*; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008047:Lip Diseases / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000473:pathology; D010386:Pelvic Neoplasms / Q000556:secondary