title: Determining the significance of MGUS.
abstract: In this issue of Blood, Turesson et al study the risk of progression of monoclonal gammopathy of undetermined significance (MGUS) to lymphoplasmacellular and myeloid malignancies in a large population, validating current risk factors and adding immunoparesis as a predictor of progression.
authors.affiliation: FONDAZIONE ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO POLICLINICO SAN MATTEO;
authors.forename: Giampaolo
authors.initials: G
authors.lastname: Merlini
mesh_terms: D005260:Female; D019337:Hematologic Neoplasms / Q000175:diagnosis*; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis*; D008297:Male; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000150:complications* / Q000175:diagnosis*; D009101:Multiple Myeloma / Q000175:diagnosis*