title: The range and role of palliative interventions for locally advanced breast cancer.
abstract: OBJECTIVE
  The role of palliative care interventions in patients with nonmetastatic disease is unclear. Locally advanced breast cancer (LABC) is such a diagnosis that presents a platform to examine the relationship of symptom management while patients are receiving treatment with curative intent.
  
  
  RESULTS
  Overwhelming physical and psychological symptoms can affect women with LABC. Fungating lesions at the time of primary presentation remain a major challenge. Treatments specifically for the treatment of fungating lesions using new dressings, topical analgesics, buccal opioids, and old techniques such as larval therapy were explored.
  
  
  CONCLUSIONS
  LABC is a complex biosocial disease that requires a collaborative interdisciplinary approach to care.
authors.affiliation: Supportive and Palliative Care, The Ottawa Hospital Cancer Centre, Ottawa, Ontario, Canada.
authors.forename: Virginia
authors.initials: V
authors.lastname: Jarvis
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology* / Q000523:psychology / Q000628:therapy*; D003646:Debridement / Q000379:methods; D003902:Detergents / Q000008:administration & dosage; D005260:Female; D006470:Hemorrhage; D006801:Humans; D017053:Infection Control / Q000379:methods; D009367:Neoplasm Staging; D009812:Odorants; D010166:Palliative Care / Q000379:methods*
chemical_list: D003902:Detergents