title: Factor v deficiency associated with congenital cardiac disorder and intracranial hemorrage.
abstract: Factor V deficiency is an inherited disorder, in which the clotting factor V is low. The disorder is very rare, occurring in only one in one million people. It is inherited as an autosomal recessive disorder. The results of coagulation studies include a prolonged prothrombin time and partial thromboplastin time associated with reduced plasma factor V content. Patients with factor V deficiency have a hemophiliac like hemorrhagic disorder. Epistaxis, bruising, and menorrhagia are some of the common features. If treatment is needed, fresh frozen plasma is typically given. In this report we present a 12 year old girl who was admitted to our clinic with recurrent nosebleeds and intracranial hemorrage after head trauma. After examination, factor V deficiency was diagnosed. She also had congenital cardiac disorder (VSD), probably a co-incidental finding.
authors.affiliation: Department of Pediatrics, GATA Haydarpaşa Teaching Hospital, Uskudar, 34668 Istanbul, Turkey.
authors.forename: Halit
authors.initials: H
authors.lastname: Ozkaya
authors.affiliation: Department of Pediatrics, GATA Haydarpaşa Teaching Hospital, Uskudar, 34668 Istanbul, Turkey.
authors.forename: A Barıs
authors.initials: AB
authors.lastname: Akcan
authors.affiliation: Department of Pediatrics, GATA Haydarpaşa Teaching Hospital, Uskudar, 34668 Istanbul, Turkey.
authors.forename: Gökhan
authors.initials: G
authors.lastname: Aydemir
authors.affiliation: Department of Pediatrics, Division of Pediatric Hemotology and Oncology, Akdeniz University, Antalya, Turkey.
authors.forename: Mediha
authors.initials: M
authors.lastname: Akcan
authors.affiliation: Department of Pediatrics, GATA Haydarpaşa Teaching Hospital, Uskudar, 34668 Istanbul, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Kul
keywords: Bleeding disorder; Factor V deficiency; İntracranial hemorrage