title: EzEditor: a versatile sequence alignment editor for both rRNA- and protein-coding genes.
abstract: EzEditor is a Java-based molecular sequence editor allowing manipulation of both DNA and protein sequence alignments for phylogenetic analysis. It has multiple features optimized to connect initial computer-generated multiple alignment and subsequent phylogenetic analysis by providing manual editing with reference to biological information specific to the genes under consideration. It provides various functionalities for editing rRNA alignments using secondary structure information. In addition, it supports simultaneous editing of both DNA sequences and their translated protein sequences for protein-coding genes. EzEditor is, to our knowledge, the first sequence editing software designed for both rRNA- and protein-coding genes with the visualization of biologically relevant information and should be useful in molecular phylogenetic studies. EzEditor is based on Java, can be run on all major computer operating systems and is freely available from http://sw.ezbiocloud.net/ezeditor/.
authors.affiliation: ChunLab, Inc., Seoul National University, Seoul, Republic of Korea.|Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Republic of Korea.
authors.forename: Yoon-Seong
authors.initials: YS
authors.lastname: Jeon
authors.affiliation: School of Biological Sciences, Seoul National University, Seoul, Republic of Korea.
authors.forename: Kihyun
authors.initials: K
authors.lastname: Lee
authors.affiliation: Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Republic of Korea.
authors.forename: Sang-Cheol
authors.initials: SC
authors.lastname: Park
authors.affiliation: ChunLab, Inc., Seoul National University, Seoul, Republic of Korea.
authors.forename: Bong-Soo
authors.initials: BS
authors.lastname: Kim
authors.affiliation: ChunLab, Inc., Seoul National University, Seoul, Republic of Korea.
authors.forename: Yong-Joon
authors.initials: YJ
authors.lastname: Cho
authors.affiliation: School of Biological Sciences, Seoul National University, Seoul, Republic of Korea.
authors.forename: Sung-Min
authors.initials: SM
authors.lastname: Ha
authors.affiliation: School of Biological Sciences, Seoul National University, Seoul, Republic of Korea.|ChunLab, Inc., Seoul National University, Seoul, Republic of Korea.|Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Republic of Korea.
authors.forename: Jongsik
authors.initials: J
authors.lastname: Chun
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D019295:Computational Biology; D010802:Phylogeny; D011381:Programming Languages; D012335:RNA, Ribosomal / Q000235:genetics*; D016415:Sequence Alignment / Q000379:methods*; D012984:Software
chemical_list: D012335:RNA, Ribosomal