title: Endoscopic resection of gastric neoplasm in solid-organ transplant recipients.
abstract: BACKGROUND
  The aim of this study was to investigate the feasibility and safety of endoscopic resection of gastric neoplasm in solid-organ transplant (SOT) recipients.
  
  
  METHODS
  Between January 1994 and December 2011, the results of endoscopic resection of 17 lesions in 15 consecutive patients who had previously undergone SOT at Asan Medical Center were retrospectively evaluated. We compared clinical outcomes of this group with 1:5 matched non-SOT patients treated by endoscopic resection.
  
  
  RESULTS
  Of the 6,491 patients who underwent SOT during the study periods, 30 patients (0.46%) with 31 lesions were diagnosed with gastric cancer, and eight patients (0.12%) with nine lesions were diagnosed with gastric adenoma. Among them, 15 patients with 17 lesions were treated by endoscopic resection, and 19 patients with 20 lesions have undergone gastrectomy. In endoscopically resected SOT group, the median duration between transplantation and endoscopic treatment was 41 months (range, 5-196 months). En bloc and complete resection were achieved in 13 (76.5%) and 15 (88.2%) lesions. Four lesions (23.5%) experienced bleeding, which was successfully managed endoscopically. When compared with post-endoscopic resection bleeding rate of non-SOT group (5.9%, [5/85]), there was no significant difference in multivariable analysis (P=0.083).
  
  
  CONCLUSIONS
  In endoscopic resection for gastric neoplasm of SOT recipients, only manageable complications were noted in some patients, and graft dysfunctions or perforations did not occur. To avoid surgical resection with its associated perioperative mortality and morbidity, endoscopic resection for gastric neoplasm in SOT recipients is recommended as a feasible treatment with high efficacy and safety.
authors.affiliation: 1 Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute, Seoul, Korea. 2 Department of Clinical Epidemiology and Biostatistics, University of Ulsan College of Medicine, Asan Medical Center, Korea. 3 Address correspondence to: Gin Hyug Lee, M.D., Ph.D., Department of Gastroenterology, University of Ulsan College of Medicine Asan Medical Center, Asan Digestive Disease Research Institute, 388-1 Pungnap-2 dong, Songpa-gu, Seoul, 138-736, Korea.
authors.forename: Shin
authors.initials: S
authors.lastname: Na
authors.forename: Gin Hyug
authors.initials: GH
authors.lastname: Lee
authors.forename: Ju Hyung
authors.initials: JH
authors.lastname: Song
authors.forename: Ji Yong
authors.initials: JY
authors.lastname: Ahn
authors.forename: Seon-Ok
authors.initials: SO
authors.lastname: Kim
authors.forename: Se Jeong
authors.initials: SJ
authors.lastname: Park
authors.forename: So-Eun
authors.initials: SE
authors.lastname: Park
authors.forename: Mi-Young
authors.initials: MY
authors.lastname: Kim
authors.forename: Jeonghoon
authors.initials: J
authors.lastname: Lee
authors.forename: Kwi-Sook
authors.initials: KS
authors.lastname: Choi
authors.forename: Do Hoon
authors.initials: DH
authors.lastname: Kim
authors.forename: Ho June
authors.initials: HJ
authors.lastname: Song
authors.forename: Kee Don
authors.initials: KD
authors.lastname: Choi
authors.forename: Hwoon-Yong
authors.initials: HY
authors.lastname: Jung
authors.forename: Jin-Ho
authors.initials: JH
authors.lastname: Kim
mesh_terms: D000368:Aged; D005260:Female; D005773:Gastroscopy; D006801:Humans; D016030:Kidney Transplantation; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000601:surgery*