title: [Granulomatous lobular mastitis associated with mammary duct ectasia: a clinicopathologic study of 32 cases with review of literature].
abstract: OBJECTIVE
  To study the clinicopathologic features of granulomatous lobular mastitis and mammary duct ectasia.
  
  
  METHODS
  The clinicopathologic data from August 2005 to May 2013 of 32 cases of granulomatous lobular mastitis and mammary duct ectasia were retrospectively reviewed.
  
  
  RESULTS
  The age of patients ranged from 26 to 45 years. Two patients had no history of delivery. Fourteen patients had no history of lactation or lactational disorder in the lesional side. Most of the remaining patients had history of breast feeding. Gross examination showed that the lesions were poorly circumscribed and varied from 3 to 12 cm in greatest dimension. Tiny abscess cavities, ranging from 0.1 to 0.5 cm in diameter and containing light yellowish to greyish secretion, were demonstrated. Histologic examination showed granuloma formation and ductal dilatation. Eleven patients had received antibiotic treatment. Twelve cases were complicated by sinus formation related to skin incision and drainage. The duration of follow-up ranged from 5 to 90 months. Three cases showed ipsilateral recurrence and 3 cases had similar pathology in the contralateral breast. Four patients defaulted follow-up.
  
  
  CONCLUSIONS
  Granulomatous lobular mastitis is associated with mammary duct ectasia. Accurate pathologic diagnosis is prudent for clinical management and control of local recurrence.
authors.affiliation: Department of Pathology, Dongzhimen Hospital, Beijing University of Chinese Medical Science, Beijing 100700, China. E-mail: chengjuan2002016@163.com.
authors.forename: Juan
authors.initials: J
authors.lastname: Cheng
authors.forename: Hua-ye
authors.initials: HY
authors.lastname: Ding
authors.forename: Yu-tang
authors.initials: YT
authors.lastname: DU
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001941:Breast Diseases / Q000150:complications / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D001942:Breast Feeding; D004108:Dilatation, Pathologic / Q000150:complications / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D058890:Granulomatous Mastitis / Q000150:complications / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D006801:Humans; D042361:Mammary Glands, Human / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies
chemical_list: D000900:Anti-Bacterial Agents; D004365:Drugs, Chinese Herbal