title: Nickel-catalyzed triarylamine synthesis: synthetic and mechanistic aspects.
abstract: An improved protocol was described for the amination of chloroarenes with diarylamines under NiCl2(PCy3)2 catalysis in the presence of a Grignard reagent as base. This method fully suits bromo-/iodoarene substrates as well, and even is expanded to certain aryl tosylates. A preliminary investigation into the mechanism suggests that this amination reaction might proceed through Ni(I) and Ni(III) intermediates rather than via the usually expected Ni(0)-Ni(II) cycle.
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China. xinxin9968@iccas.ac.cn yanglm@iccas.ac.cn.
authors.forename: Xin-Le
authors.initials: XL
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Wu
authors.forename: Xin-Heng
authors.initials: XH
authors.lastname: Fan
authors.forename: Lian-Ming
authors.initials: LM
authors.lastname: Yang