title: It ain't what you do, it's the way you do it: five golden rules for transforming prostate-specific antigen screening.
abstract: The benefit-harm ratio of PSA screening can be dramatically improved by avoiding screening, biopsy and treatment in men who are unlikely to benefit, and by referring men that do need treatment to high volume centers.
authors.affiliation: Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. Electronic address: vickersa@mskcc.org.
authors.forename: Andrew
authors.initials: A
authors.lastname: Vickers
authors.affiliation: Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; Department of Urology, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden.
authors.forename: Sigrid
authors.initials: S
authors.lastname: Carlsson
authors.affiliation: Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
authors.forename: Vincent
authors.initials: V
authors.lastname: Laudone
authors.affiliation: Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; Departments Medicine and Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.
authors.forename: Hans
authors.initials: H
authors.lastname: Lilja
mesh_terms: D001706:Biopsy; D055088:Early Detection of Cancer / Q000379:methods* / Q000592:standards; D061847:Hospitals, High-Volume; D006801:Humans; D007258:Informed Consent; D008297:Male; D011467:Prostate / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000097:blood*; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology* / Q000601:surgery; D018570:Risk Assessment
chemical_list: D017430:Prostate-Specific Antigen