title: Synthesis of the 6,6,5,7-tetracyclic core of daphnilongeranin B.
abstract: An efficient approach toward the synthesis of the 6,6,5,7-tetracyclic core of the daphnilongeranin B, a Daphniphyllum alkaloid, is reported. The bridged 6,6-bicyclic system was constructed using a gold(i) catalysed Conia-ene reaction, while the 5- and 7-membered rings were assembled by two diastereoselective Michael addition reactions, respectively.
authors.affiliation: Natural Products Research Centre, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China. shaohw@cib.ac.cn.
authors.forename: Xiaochun
authors.initials: X
authors.lastname: Xiong
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
authors.forename: Zhaoyong
authors.initials: Z
authors.lastname: Lu
authors.forename: Ming
authors.initials: M
authors.lastname: Wan
authors.forename: Jun
authors.initials: J
authors.lastname: Deng
authors.forename: Shuhang
authors.initials: S
authors.lastname: Wu
authors.forename: Huawu
authors.initials: H
authors.lastname: Shao
authors.forename: Ang
authors.initials: A
authors.lastname: Li
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis*; D002384:Catalysis; D015394:Molecular Structure; D011083:Polycyclic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D011083:Polycyclic Compounds; C558838:daphnilongeranin B