title: [The extraction technology of epigoitri from isatidis radix by supercritical CO2 fluid].
abstract: OBJECTIVE
  To study the extraction technology of epigoitri from Isatidis Radix by supercritical CO2 fluid.
  
  
  METHODS
  The effects of pressure, temperature, time, concentration and dosage of alcohol were studied by single factor analysis and orthogonal test.
  
  
  RESULTS
  The optimized conditions were as follows: The pressure was 20 MPs, the temperature was 50 degrees C, the time was 2 h, concentration of alcohol was 100%, dosage was 80 mL. The content of epigoitri in the extract could reach 38.63% under the above conditions.
  
  
  CONCLUSIONS
  This method is simple, rapid and it is suitable for the extraction of epigoitri from Isatidis Radix.
authors.affiliation: Wannan Medicine College, Wuhu 241002, China. niansihui@sina.com
authors.forename: Si-Hui
authors.initials: SH
authors.lastname: Nian
authors.affiliation: Wannan Medicine College, Wuhu 241002, China.
authors.forename: Chun-Yun
authors.initials: CY
authors.lastname: Liu
authors.affiliation: Anhui College of Chinese Traditional Medicine, Wuhu 241000, China.
authors.forename: Li-Min
authors.initials: LM
authors.lastname: Liu
authors.affiliation: Wannan Medicine College, Wuhu 241002, China.
authors.forename: Li-Fen
authors.initials: LF
authors.lastname: Yang
mesh_terms: D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D031219:Isatis / Q000737:chemistry*; D023303:Oxazolidinones / Q000302:isolation & purification*; D018517:Plant Roots / Q000737:chemistry; D011312:Pressure; D015203:Reproducibility of Results; D012997:Solvents / Q000737:chemistry; D013696:Temperature; D013997:Time Factors
chemical_list: D004365:Drugs, Chinese Herbal; D023303:Oxazolidinones; D012997:Solvents; D002245:Carbon Dioxide; C004333:goitrin