title: Intermolecular/intramolecular sequential aldol reaction.
abstract: The first example of intermolecular/intramolecular sequential aldol reaction of disilyl enol ethers is described. This strategy enables the formation of five-, six-, and seven-membered ring products. Four or more contiguous stereogenic centers are created with high levels of relative stereochemical control.
authors.affiliation: Molecular Catalyst Research Center, Chubu University , 1200 Matsumoto-cho, Kasugai 487-8501, Japan.
authors.forename: Atsuto
authors.initials: A
authors.lastname: Izumiseki
authors.forename: Hisashi
authors.initials: H
authors.lastname: Yamamoto
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D004987:Ethers / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D000447:Aldehydes; D004987:Ethers; D007659:Ketones