title: Assessment of some biochemical oxidative stress markers in male smokers with chronic periodontitis.
abstract: The present study aims to assess and compare the biochemical oxidative stress markers in male smokers and non-smokers with chronic periodontitis. One hundred thirty-four male chronic periodontitis patients and 64 apparently healthy male volunteers were recruited for the study. The periodontal status was evaluated by measuring gingival index, plaque index, papillary bleeding index and clinical attachment loss using UNC-15 probe. The biochemical markers estimated were total antioxidant capacity, RBC-superoxide dismutase, glutathione peroxidase, vitamin C, malondialdehyde and C-reactive protein. The obtained results indicate higher oxidative stress in chronic periodontitis. Smokers with chronic periodontitis show significantly higher periodontal clinical parameters and relatively higher systemic oxidative stress. Vitamin C estimation may be an important biochemical parameter in conjunction with clinical parameters for diagnosis of chronic periodontitis in smokers.
authors.affiliation: Department of Biochemistry, Grant Medical College and Sir J. J. Group of Hospitals, Mumbai, Maharashtra India.
authors.forename: Abdul Samad
authors.initials: AS
authors.lastname: Aziz
authors.affiliation: Department of Biochemistry, Grant Medical College and Sir J. J. Group of Hospitals, Mumbai, Maharashtra India.
authors.forename: Madhav Govind
authors.initials: MG
authors.lastname: Kalekar
authors.affiliation: Maharashtra University of Health Sciences, Nashik, Maharashtra India.
authors.forename: Adinath Narayan
authors.initials: AN
authors.lastname: Suryakar
authors.affiliation: Department of Dentistry, Grant Medical College and Sir J. J. Group of Hospitals, Mumbai, Maharashtra India.
authors.forename: Tabita
authors.initials: T
authors.lastname: Benjamin
authors.affiliation: Department of Biotechnology, Sinhgad College of Science, Ambegaon (Bk), Pune, Maharashtra India.
authors.forename: Milsee Jaya
authors.initials: MJ
authors.lastname: Prakashan
authors.affiliation: Department of Pedodontics, M.A. Rangoonwala College of Dental Sciences and Research Center, Pune, Maharashtra India.
authors.forename: Bijle Mohammed Nadeem
authors.initials: BM
authors.lastname: Ahmed
authors.affiliation: Department of Statistics, Abeda Inamdar Senior College, Pune, Maharashtra India.
authors.forename: Mehmood
authors.initials: M
authors.lastname: Sayyad
keywords: Biochemical oxidative stress markers; Chronic periodontitis; Oxidative stress; Smoking