title: Severe systemic infection masking underlying childhood leukemia.
abstract: Severe childhood infections can occasionally be accompanied by bone marrow suppression. It is unusual for infection induced marrow aplasia to evolve into acute leukemia. We share our experience in managing four children with severe sepsis and pancytopenia which in due course evolved into acute leukemia. This report emphasizes that sepsis related pancytopenia can be a harbinger of evolving hematopoietic disorders.
authors.affiliation: Pediatric Hematology Oncology unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
authors.forename: Aruna
authors.initials: A
authors.lastname: Rajendran
authors.affiliation: Pediatric Hematology Oncology unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
authors.forename: Amita
authors.initials: A
authors.lastname: Trehan
authors.affiliation: Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Jasmina
authors.initials: J
authors.lastname: Ahluwalia
authors.affiliation: Pediatric Hematology Oncology unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
authors.forename: Ram Kumar
authors.initials: RK
authors.lastname: Marwaha
keywords: Acute lymphoblastic leukemia; Children; Infection associated pancytopenia; Spontaneous remission