title: Clarithromycin induced psoriasis in a 37-year old man.
abstract: Many drugs may induce psoriatic lesions or exacerbate preexisting psoriasis. We report an exceptional case of psoriasis vulgaris probably induced by clarithromycin. A 37-year-old man was prescribed for pharyngitis clarithromycin 500mg twice a day. On the third day of treatment, he presented a non pruriginous erythemato-squamous eruption, of trunk and limbs. Skin biopsy showed a typical aspect of psoriasis vulgaris. The drug was interrupted and the patient was treated by topical corticoids with rapid improvement.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Zaiem
authors.forename: Amel
authors.initials: A
authors.lastname: Mebazaa
authors.forename: Ghozlane
authors.initials: G
authors.lastname: Lakhoua
authors.forename: Talel
authors.initials: T
authors.lastname: Badri
authors.forename: Rym
authors.initials: R
authors.lastname: Sahnoun
authors.forename: Sarrah
authors.initials: S
authors.lastname: Kastalli
authors.forename: Riadh
authors.initials: R
authors.lastname: Daghfous
authors.affiliation: National Center of Pharmacovigilance, 9 Avenue du Dr Zouhaier Essafi 1006, Tunis, Tunisia. ahmed.zaiem@rns.tn.
authors.forename: Sihem
authors.initials: S
authors.lastname: El Aidli
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001623:Betamethasone / Q000008:administration & dosage / Q000627:therapeutic use; D017291:Clarithromycin / Q000009:adverse effects*; D003875:Drug Eruptions / Q000473:pathology; D006801:Humans; D008297:Male; D011565:Psoriasis / Q000139:chemically induced*; D012867:Skin / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D001623:Betamethasone; D017291:Clarithromycin