title: Fe(HSO4)3/SiO2: an efficient and heterogeneous catalyst for one-pot synthesis of 2-aryl-chromene-4-ones (flavanones).
abstract: Silica ferric hydrogensulphate is an efficient heterogeneous catalyst for cyclisation of 2-hydroxychalcones to their corresponding flavanones (chromanone). This intramolecular oxa-Michael reaction was carried out in high yields in the presence of electron donating and electron withdrawing groups in the chalcone structure. Also, we found that aniline can act as an organic co-catalyst in direct synthesis of flavanones from 2-hydroxyacethophenone and aldehydes in the presence of Fe(HSO4)3/SiO2. Flavanones were prepared in high yields in a new catalytic system with similar substituted effect in the indirect cyclisation method. The catalyst in all the above reactions is reusable without significant decreases in its activity after four times of recycling.
authors.affiliation: a Department of Chemistry , School of Sciences, Ferdowsi University of Mashhad , Mashhad 91775-1436 , Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Eshghi
authors.forename: Mohammad
authors.initials: M
authors.lastname: Rahimizadeh
authors.forename: Seyed Mohsen
authors.initials: SM
authors.lastname: Mousavi
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D001578:Benzopyrans / Q000737:chemistry; D002384:Catalysis; D002599:Chalcone / Q000737:chemistry; D005290:Ferric Compounds / Q000737:chemistry*; D044950:Flavanones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012822:Silicon Dioxide / Q000737:chemistry*; D013431:Sulfates / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D001578:Benzopyrans; D005290:Ferric Compounds; D044950:Flavanones; D013431:Sulfates; D002599:Chalcone; D012822:Silicon Dioxide