title: Diffusion tensor imaging of pyramidal tract reorganization after pediatric stroke.
abstract: BACKGROUND
  Plasticity of the developing motor tracts is a contributor to recovery of motor function after pediatric stroke. The mechanism of these plastic changes may be functional and/or structural in nature. The corticospinal tract (CST) represents the major pathway responsible for voluntary movement. Stroke-induced damage to the CST as well as to other motor tracts leads to motor deficits which may show favorable functional recovery particularly in the pediatric population.
  
  
  METHODS
  We report the case of a 3-year-old girl demonstrating reorganization of the pyramidal tracts after an extensive left MCA territory stroke secondary to head trauma. Reorganization is characterized using serial diffusion tensor imaging (DTI) of the pyramidal tracts which contain the CST.
  
  
  RESULTS
  Imaging shows decreased ipsi-lesional fractional anisotropy (FA) suggestive of Wallerian degeneration and increased contralesional FA.
  
  
  CONCLUSIONS
  These results point to plastic reorganization of the pyramidal tract post-stroke and the utility of DTI in recognizing these changes.
authors.affiliation: Department of Neurosurgery, Weill Cornell Medical College, 525 East 68th Street, Box 99, New York, NY, 10065, USA.
authors.forename: Emilie
authors.initials: E
authors.lastname: George
authors.forename: Linda
authors.initials: L
authors.lastname: Heier
authors.forename: Ilhami
authors.initials: I
authors.lastname: Kovanlikaya
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Greenfield
mesh_terms: D016880:Anisotropy; D002675:Child, Preschool; D056324:Diffusion Tensor Imaging; D005260:Female; D006801:Humans; D020768:Middle Cerebral Artery / Q000473:pathology; D011712:Pyramidal Tracts / Q000473:pathology* / Q000503:physiopathology*; D020521:Stroke / Q000473:pathology*; D014855:Wallerian Degeneration / Q000209:etiology