title: Phaeohyphomycotic dermatitis in a giant panda (Ailuropoda melanoleuca) caused by Cladosporium cladosporioides.
abstract: We report here a clinical case of phaeohyphomycosis in an 18-year-old male giant panda (Ailuropoda melanoleuca). Skin lesions on the giant panda disappeared following 2 months of treatment with ketoconazole. Three months after discontinuing the treatment, there was a clinical and mycological relapse. The disease progression was no longer responsive to ketoconazole. Microscopy and polymerase chain reaction (PCR) analysis revealed that the infection was caused by Cladosporium cladosporioides. A 4-month treatment regime with Itraconazole oral solution (700 mg per day) successfully terminated the infection.
authors.affiliation: College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China ; College of Veterinary Medicine, Sichuan Agricultural University, Ya'an 625014, China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Ya'an 625014, China.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Ma
authors.affiliation: College of Life and Basic Sciences, Sichuan Agricultural University, Ya'an 625014, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Gu
authors.affiliation: College of Veterinary Medicine, Sichuan Agricultural University, Ya'an 625014, China ; China Conservation and Research Center for the Giant Panda, Ya'an, Sichuan 625000, China.
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Liu
authors.affiliation: College of Veterinary Medicine, Sichuan Agricultural University, Ya'an 625014, China ; China Conservation and Research Center for the Giant Panda, Ya'an, Sichuan 625000, China.
authors.forename: Desheng
authors.initials: D
authors.lastname: Li
authors.affiliation: China Conservation and Research Center for the Giant Panda, Ya'an, Sichuan 625000, China.
authors.forename: Shanshan
authors.initials: S
authors.lastname: Ling
authors.affiliation: College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
authors.forename: Jiafa
authors.initials: J
authors.lastname: Hou
authors.affiliation: College of Veterinary Medicine, Sichuan Agricultural University, Ya'an 625014, China ; China Conservation and Research Center for the Giant Panda, Ya'an, Sichuan 625000, China.
authors.forename: Chengdong
authors.initials: C
authors.lastname: Wang
authors.affiliation: College of Veterinary Medicine, Sichuan Agricultural University, Ya'an 625014, China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Ya'an 625014, China.
authors.forename: Sanjie
authors.initials: S
authors.lastname: Cao
authors.affiliation: College of Veterinary Medicine, Sichuan Agricultural University, Ya'an 625014, China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Ya'an 625014, China.
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Huang
authors.affiliation: College of Veterinary Medicine, Sichuan Agricultural University, Ya'an 625014, China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Ya'an 625014, China.
authors.forename: Xintian
authors.initials: X
authors.lastname: Wen
authors.affiliation: College of Life and Basic Sciences, Sichuan Agricultural University, Ya'an 625014, China.
authors.forename: Jiaxue
authors.initials: J
authors.lastname: Ruan
authors.affiliation: College of Veterinary Medicine, Sichuan Agricultural University, Ya'an 625014, China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Ya'an 625014, China.
authors.forename: Cao
authors.initials: C
authors.lastname: Dong
authors.affiliation: College of Veterinary Medicine, Sichuan Agricultural University, Ya'an 625014, China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Ya'an 625014, China.
authors.forename: Changcheng
authors.initials: C
authors.lastname: Li
authors.affiliation: College of Veterinary Medicine, Sichuan Agricultural University, Ya'an 625014, China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Ya'an 625014, China.
authors.forename: Yufei
authors.initials: Y
authors.lastname: Tong
keywords: Cladosporium cladosporioides; Itraconazole; Phaeohyphomycosis; Polymerase chain reaction