title: Mycobacteriosis in a domestic ferret (Mustela putorius furo).
abstract: A 4-year-old spayed female ferret presented with a 2-month history of anorexia, vomiting and occasional diarrhea. Abdominal ultrasonography revealed thickening of the gastric wall and enlarged abdominal lymph nodes. Biopsy samples from the thickened gastric wall, enlarged abdominal lymph nodes and liver were taken during an exploratory laparotomy. Based on the histopathological examination, mycobacterium infection was diagnosed. The bacterial species could not be identified by additional diagnostic tests of feces, including fecal smear, culture and polymerase chain reaction (PCR). The ferret was treated with prednisolone and multiple antimicrobials, including rifampicin, azithromycin and enrofloxacin, but did not improve with treatment and died 220 days after the first presentation.
authors.affiliation: Miwa Exotic Animal Hospital, 1-25-5 Komagome, Toshima-ku, Tokyo 170-0003, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Nakata
authors.forename: Yasutsugu
authors.initials: Y
authors.lastname: Miwa
authors.forename: Masaya
authors.initials: M
authors.lastname: Tsuboi
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Uchida
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use; D000077422:Enrofloxacin; D017809:Fatal Outcome; D005260:Female; D005289:Ferrets / Q000382:microbiology*; D024841:Fluoroquinolones / Q000627:therapeutic use; D006400:Hematocrit / Q000662:veterinary; D006652:Histological Techniques / Q000662:veterinary; D007813:Laparotomy / Q000662:veterinary; D007958:Leukocyte Count / Q000662:veterinary; D009164:Mycobacterium Infections / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D011239:Prednisolone / Q000627:therapeutic use; D012293:Rifampin / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D000077422:Enrofloxacin; D017963:Azithromycin; D011239:Prednisolone; D012293:Rifampin