title: Bone regeneration in extraction sockets with autologous platelet rich fibrin gel.
abstract: OBJECTIVE
  To evaluate the effects of autologous platelet rich fibrin gel (PRF gel) on bone regeneration following extraction.
  
  
  METHODS
  The study design was approved by the Institutional Ethical Committee. Study sample consisting of a total of 22 patients requiring bilateral transalveolar third molar extractions were included after written informed consent. One side was randomly chosen as case and the other side was the control. Autologous PRF gel was prepared from Fresh blood obtained from the patient. The PRF gel was placed in the extraction site and primary closure was obtained. The patient was called for a follow up on the first post op day, 1st week, one month, three month and six months post op. Regeneration of bone was measured using serial radiographs (RVG) at immediate post op, one, three and six months. This was then compared with the bone regeneration seen in the control group, with the radiographs taken at same intervals, to estimate the difference in bone regeneration if any. RVGs were assessed for amount of radiologic bone filling by the method described by Matteo Chiapasco et al.
  
  
  CONCLUSIONS
  Higher mean pixels was recorded in cases compared to controls at all the time intervals viz., immediate post op, 1 month post op, 3 months post op and 6 months post op. However, the difference in the mean pixels recorded between the two groups was not statistically significant (P > 0.05). For complete analysis, further follow up of the present patients and a larger sample size is required to obtain a conclusive result of the Bone Regeneration in extraction sockets with PRF gel.
authors.affiliation: Department of Oral and Maxillofacial Surgery, DAPMRV Dental College & Hospital, Bangalore, 560078 India.
authors.forename: S
authors.initials: S
authors.lastname: Girish Rao
authors.affiliation: Department of Oral and Maxillofacial Surgery, DAPMRV Dental College & Hospital, Bangalore, 560078 India.
authors.forename: Preethi
authors.initials: P
authors.lastname: Bhat
authors.affiliation: Department of Oral Medicine and Radiology, DAPMRV Dental College & Hospital, Bangalore, 560078 India.
authors.forename: K S
authors.initials: KS
authors.lastname: Nagesh
authors.affiliation: Department of Biomedical Engineering Institute, University of Minnesota, Minneapolis, MN USA.
authors.forename: Gundu H R
authors.initials: GH
authors.lastname: Rao
authors.affiliation: Department of Pathology, DAPMRV Dental College & Hospital, Bangalore, 560078 India.
authors.forename: Bharthi
authors.initials: B
authors.lastname: Mirle
authors.affiliation: Department of Oral and Maxillofacial Surgery, DAPMRV Dental College & Hospital, Bangalore, 560078 India.
authors.forename: Lubna
authors.initials: L
authors.lastname: Kharbhari
authors.affiliation: Department of Oral and Maxillofacial Surgery, DAPMRV Dental College & Hospital, Bangalore, 560078 India.
authors.forename: B
authors.initials: B
authors.lastname: Gangaprasad
keywords: Bone regeneration; Platelet gel; Platelet rich fibrin; Post extraction socket