title: An efficient synthesis of 2,5-diimino-furans via Pd-catalyzed cyclization of bromoacrylamides and isocyanides.
abstract: A novel palladium-catalyzed cyclization of bromoacrylamides with isocyanides gives substituted 2,5-diimino-furans, which can be used as the precursor of maleamides. This synthesis likely proceeds, after isonitrile insertion into C–Pd(II) bond, through the coordination of the amide oxygen atom to the Pd(II) centre as a key step.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China. jianghf@scut.edu.cn.
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
authors.forename: Meizhou
authors.initials: M
authors.lastname: Yin
authors.forename: Yibiao
authors.initials: Y
authors.lastname: Li
authors.forename: Bifu
authors.initials: B
authors.lastname: Liu
authors.forename: Jinwu
authors.initials: J
authors.lastname: Zhao
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
mesh_terms: D000178:Acrylamides / Q000737:chemistry*; D002384:Catalysis; D003486:Cyanides / Q000737:chemistry*; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000178:Acrylamides; D003486:Cyanides; D005663:Furans; D009942:Organometallic Compounds; D010165:Palladium