title: Diagnosis, management and outcomes of necrotising soft tissue infection within a Plastic and Reconstructive Surgery unit.
abstract: OBJECTIVE
  Necrotising soft tissue infection (NSTI) is an extremely serious condition that relies on a high index of suspicion, prompt diagnosis and emergent radical surgical treatment. We explored the presentation, management and outcomes of NSTI within our department. We also assessed the potential benefit of using risk predictor scoring system.
  
  
  METHODS
  Retrospective review using departmental electronic database and hospital records.
  
  
  RESULTS
  Twenty-four patients were treated for NSTI within our department between 2004 and 2010. Seventeen presented in our hospital to various surgical and medical teams. All patients presented with pain, swelling, erythema and tenderness at palpation. Only 40% of necrotising fasciitis and 28.6% of Fournier's gangrene were diagnosed as NSTI at initial assessment. Average mean interval time from admission to primary surgery was 17.7 h and 4 h from diagnosis to primary surgery. There were four mortalities. The average risk predictor Laboratory Risk Indicator for Necrotising Fasciitis score was 7.9. Significant morbidities post-operatively included bowel stoma, long-term urinary catheter and new diagnoses of carcinomas.
  
  
  CONCLUSIONS
  Physicians and surgeons need to be suspicious of NSTI in severe cases of soft tissue infection to prevent delay in diagnosis and life-saving treatment. Scoring system can be used judiciously as adjunct to aid diagnosis.
authors.affiliation: Specialty Trainee in Trauma and Orthopaedic Surgery, Department of Trauma and Orthopaedic Surgery, James Cook University Hospital, Middlesbrough, UK.
authors.forename: Ling Hong
authors.initials: LH
authors.lastname: Lee
authors.forename: Richard
authors.initials: R
authors.lastname: Chalmers
authors.forename: Tobian
authors.initials: T
authors.lastname: Muir
mesh_terms: D000328:Adult; D000368:Aged; D002481:Cellulitis / Q000175:diagnosis; D003646:Debridement; D003937:Diagnosis, Differential; D019115:Fasciitis, Necrotizing / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018461:Soft Tissue Infections / Q000150:complications*; D013518:Surgery, Plastic; D016896:Treatment Outcome
keywords: Fournier’s gangrene; Necrotising soft tissue infection; diagnosis; management; necrotising fasciitis