title: Magnetic core-shell Fe₃O₄@SiO₂/MWCNT nanocomposite modified carbon paste electrode for amplified electrochemical sensing of uric acid.
abstract: A new type of nanocomposite based on multi-walled carbon nanotubes decorated with magnetic core-shell Fe3O4@SiO2 nanoparticles (Fe3O4@SiO2/MWCNTs) was prepared and used to fabricate a modified carbon paste electrode (CPE). The nanocomposite was characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX) and Fourier transform infrared spectroscopy (FT-IR) techniques. Electrochemical behavior of uric acid (UA) was investigated on Fe3O4@SiO2/MWCNTs-CPE by cyclic voltammetry (CV) and square wave voltammetry (SWV) in phosphate buffer solution (pH6.0). Under the optimized conditions, the peak currents increased linearly with the concentration of UA in the range from 0.60 to 100.0 μM, with a detection limit of 0.13 μM. The proposed sensor was successfully applied for the determination of UA in biological fluids.
authors.affiliation: Department of Chemistry, Faculty of Science, University of Guilan, Namjoo Street, P.O. Box: 1914, Rasht, Iran. Electronic address: arvand@guilan.ac.ir.
authors.forename: Majid
authors.initials: M
authors.lastname: Arvand
authors.affiliation: Department of Chemistry, Faculty of Science, University of Guilan, Namjoo Street, P.O. Box: 1914, Rasht, Iran.
authors.forename: Morassa
authors.initials: M
authors.lastname: Hassannezhad
mesh_terms: D002138:Calibration; D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D052203:Ferrosoferric Oxide / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D015203:Reproducibility of Results; D012822:Silicon Dioxide / Q000737:chemistry*; D012996:Solutions; D017550:Spectroscopy, Fourier Transform Infrared; D013997:Time Factors; D014527:Uric Acid / Q000032:analysis* / Q000097:blood / Q000652:urine
chemical_list: D037742:Nanotubes, Carbon; D012996:Solutions; D014527:Uric Acid; D012822:Silicon Dioxide; D052203:Ferrosoferric Oxide
keywords: Magnetic core–shell Fe(3)O(4)@SiO(2) nanoparticles; Multi-walled carbon nanotubes; Nanocomposite; Uric acid