title: Clinical experience with insulin detemir type 2 diabetes mellitus, biphasic insulin aspart and insulin aspart in people with type 2 diabetes: Results from the Rabat-Sale-Zemmour-Zaer Region cohort of the A1chieve study.
abstract: BACKGROUND
  The A1chieve, a multicentric (28 countries), 24-week, non-interventional study evaluated the safety and effectiveness of insulin detemir, biphasic insulin aspart and insulin aspart in people with T2DM (n = 66 726) in routine clinical care across four continents.
  
  
  METHODS
  Data was collected at baseline, at 12 weeks and at 24 weeks. This short communication presents the results for patients enrolled from Rabat-Sale-Zemmour-Zaer region, Morocco.
  
  
  RESULTS
  A total of 424 patients were enrolled in the study. Four different insulin analogue regimens were used in the study. Study patients had started on or were switched to biphasic insulin aspart (n = 177), insulin detemir (n = 150), insulin aspart (n = 11), basal insulin plus insulin aspart (n = 45) and other insulin combinations (n = 41). At baseline glycaemic control was poor for both insulin naïve (mean HbA1c: 10.1%) and insulin user (mean HbA1c: 9.4%) groups. After 24 weeks of treatment, all the study groups showed improvement in HbA1c (insulin naïve: -2.5%, insulin users: -1.8%). Major hypoglycaemia was observed in the insulin user group after 24 weeks (0.1 events/patient-year). SADRs were reported in 0.5% of insulin users.
  
  
  CONCLUSIONS
  Starting or switching to insulin analogues was associated with improvement in glycaemic control with a low rate of hypoglycaemia.
authors.affiliation: Department of Endocrinology and Metabolic diseases, Avicenne University Hospital, Rabat-Sale-Zemmour-Zaer, Morocco.
authors.forename: Abdelmjid
authors.initials: A
authors.lastname: Chraibi
authors.affiliation: Department of Endocrinology and Diabetology, Military hospital of instruction Mohammed V, Rabat-Sale-Zemmour-Zaer, Morocco.
authors.forename: Ghizlane
authors.initials: G
authors.lastname: Belmejdoub
keywords: A1chieve study; Rabat-Sale-Zemmour-Zaer; insulin analogues; type 2 diabetes mellitus