title: Primary orbital melanoma combined with giant divided nevus of the eyelid.
abstract: The authors report a rare case of primary orbital melanoma (POM) combined with giant divided nevus of the eyelid. An 8-year-old Chinese girl is referred for evaluation of 2-month duration of exophthalmos with decreased vision, epiphora, and pain on her right eye. His presentation, imaging, biopsy, histopathology, and management are presented. The possible cellular origin of the POM and the relationship of POM and divided nevus are discussed. We presume that divided nevus may be one of rarely preexisting lesions of POM.
authors.affiliation: From the *Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute; †Tianjin Medical University Eye Hospital; ‡Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Clinical College of Ophthalmology Tianjin Medical University; and §Pathology Department, Tianjin Medical University General Hospital, Tianjin, China.
authors.forename: Yifeng
authors.initials: Y
authors.lastname: Ke
authors.forename: Xinjun
authors.initials: X
authors.lastname: Ren
authors.forename: Liming
authors.initials: L
authors.lastname: Zhu
authors.forename: Rui
authors.initials: R
authors.lastname: Hao
authors.forename: Wenjin
authors.initials: W
authors.lastname: Song
authors.forename: Xun
authors.initials: X
authors.lastname: Liu
authors.forename: Yanjin
authors.initials: Y
authors.lastname: He
mesh_terms: D001706:Biopsy; D002648:Child; D005142:Eyelid Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005143:Eyelids / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008545:Melanoma / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009508:Nevus, Pigmented / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009915:Orbit / Q000473:pathology; D017233:Orbit Evisceration; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery