title: Polycyclic aromatic hydrocarbon body residues and lysosomal membrane destabilization in mussels exposed to the Dubai Star bunker fuel oil (intermediate fuel oil 380) spill in San Francisco Bay.
abstract: Following the spill of bunker fuel oil (intermediate fuel oil 380, approximately 1500-3000 L) into San Francisco Bay in October 2009, polycyclic aromatic hydrocarbon (PAH) concentrations in mussels from moderately oiled areas increased up to 87 554 ng/g (dry wt) and, 3 mo later, decreased to concentrations found in mussels collected prior to oiling, with a biological half-life of approximately 16 d. Lysosomal membrane destabilization increased in mussels with higher PAH body burdens.
authors.affiliation: Department of Civil and Environmental Engineering, University of California, Davis, California, USA.
authors.forename: Hyun-Min
authors.initials: HM
authors.lastname: Hwang
authors.forename: Beckye
authors.initials: B
authors.lastname: Stanton
authors.forename: Toby
authors.initials: T
authors.lastname: McBride
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Anderson
mesh_terms: D000818:Animals; D061006:Bays; D049872:Bivalvia / Q000737:chemistry*; D006207:Half-Life; D007425:Intracellular Membranes / Q000187:drug effects; D008247:Lysosomes / Q000187:drug effects; D059392:Petroleum Pollution; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis* / Q000633:toxicity; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000633:toxicity
chemical_list: D011084:Polycyclic Aromatic Hydrocarbons; D014874:Water Pollutants, Chemical
keywords: Critical body residue; Lysosomal destabilization; Oil spill; Polycyclic aromatic hydrocarbon; Screening; Toxicokinetics