title: [A psychocardiology update on depression and coronary heart disease].
abstract: The prevalence of a major depressive disorder in patients after myocardial infarction is 20%. Depression is a risk factor for incident coronary heart disease and poor prognosis after myocardial infarction. Poor lifestyle habits and adherence to cardiac therapy as well as metabolic and pathophysiologic changes may partially explain this link. The threatening experience of an acute coronary event and immune and inflammatory changes may be unique features contributing to incident depression after myocardial infarction. While psychotherapy, antidepressants, and physical exercise may alleviate depressive symptoms in patients with coronary heart disease, cardiac rehabilitation additionally reduces mortality risk. Attempts are being undertaken to identify the cardiotoxic characteristics of depression to develop even more effective therapies in the future.
authors.affiliation: Kompetenzbereich für Psychosomatische Medizin, Klinik für Allgemeine Innere Medizin, Universitätsspital, Inselspital, Bern und Departement für Klinische Forschung, Universität Bern.
authors.forename: Roland
authors.initials: R
authors.lastname: von Känel
mesh_terms: D015897:Comorbidity; D003327:Coronary Disease / Q000175:diagnosis / Q000401:mortality / Q000523:psychology*; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000401:mortality / Q000523:psychology*; D006801:Humans; D055809:Illness Behavior; D008403:Mass Screening; D009203:Myocardial Infarction / Q000175:diagnosis / Q000401:mortality / Q000523:psychology; D010349:Patient Compliance / Q000523:psychology; D012008:Recurrence; D016019:Survival Analysis
keywords: Depression; Entzündung; Myokardinfarkt; Therapie; depression; infarctus du myocarde; inflammation; myocardial infarction; psychological stress; psychologischer Stress; stress psychologique; therapy; thérapie