title: Selinexor suppresses downstream effectors of B-cell activation, proliferation and migration in chronic lymphocytic leukemia cells.
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhong
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: D
authors.initials: D
authors.lastname: El-Gamal
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Dubovsky
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: K A
authors.initials: KA
authors.lastname: Beckwith
authors.affiliation: Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: B K
authors.initials: BK
authors.lastname: Harrington
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: K E
authors.initials: KE
authors.lastname: Williams
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: V M
authors.initials: VM
authors.lastname: Goettl
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: S
authors.initials: S
authors.lastname: Jha
authors.affiliation: Center for Biostatistics, The Ohio State University, Columbus, OH, USA.
authors.forename: X
authors.initials: X
authors.lastname: Mo
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Jones
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Flynn
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: K J
authors.initials: KJ
authors.lastname: Maddocks
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Andritsos
authors.affiliation: Karyopharm Therapeutics Inc., Natick, MA, USA.
authors.forename: D
authors.initials: D
authors.lastname: McCauley
authors.affiliation: Karyopharm Therapeutics Inc., Natick, MA, USA.
authors.forename: S
authors.initials: S
authors.lastname: Shacham
authors.affiliation: Karyopharm Therapeutics Inc., Natick, MA, USA.
authors.forename: M
authors.initials: M
authors.lastname: Kauffman
authors.affiliation: 1] Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA [2] Division of Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Byrd
authors.affiliation: Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: R
authors.initials: R
authors.lastname: Lapalombella
mesh_terms: D001402:B-Lymphocytes / Q000187:drug effects* / Q000276:immunology; D002465:Cell Movement / Q000187:drug effects*; D049109:Cell Proliferation / Q000187:drug effects*; D006801:Humans; D006834:Hydrazines / Q000494:pharmacology*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000276:immunology / Q000473:pathology*; D008213:Lymphocyte Activation / Q000187:drug effects*; D014230:Triazoles / Q000494:pharmacology*
chemical_list: D006834:Hydrazines; D014230:Triazoles; C585161:selinexor