title: Sensitive and selective plasmonic assay for spermine as biomarker in human urine.
abstract: A simple, fast, and highly selective and sensitive colorimetric assay to detect nanomolar levels of spermine in human urine (healthy donors, cancer patients) is reported. This assay is based on the absence of a competitive organic capping on the gold nanoparticles together with the high affinity of the amine groups of the analyte for the nanoparticle surface.
authors.affiliation: Departamento de Química Analítica, Facultad de Química, Universidad de Valencia , Dr. Moliner 50, 46100, Burjassot, Valencia, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Jornet-Martínez
authors.forename: María
authors.initials: M
authors.lastname: González-Béjar
authors.forename: Y
authors.initials: Y
authors.lastname: Moliner-Martínez
authors.forename: P
authors.initials: P
authors.lastname: Campíns-Falcó
authors.forename: Julia
authors.initials: J
authors.lastname: Pérez-Prieto
mesh_terms: D015415:Biomarkers / Q000652:urine; D003124:Colorimetry / Q000379:methods*; D006046:Gold / Q000737:chemistry; D006801:Humans; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry; D013096:Spermine / Q000652:urine*; D016482:Urinalysis / Q000379:methods*
chemical_list: D015415:Biomarkers; D013096:Spermine; D006046:Gold