title: Chinese multi-institutional registry (CMIR) for resected non-small cell lung cancer: survival analysis of 5,853 cases.
abstract: BACKGROUND
  Concerns on surgical treatment of non-small cell lung cancer (NSCLC) have been increasing recent years. However, the significance of previous studies based on single center or regional experience in China was impaired by small sample size. Here we described a Chinese Multi-institutional Registry (CMIR) to address this disadvantage and proposed a further collaboration project.
  
  
  METHODS
  Information of patients diagnosed with stage I to III NSCLC who underwent radical resection between 2001 and 2008 in seven institutions from the People's Republic of China was collected using a blinded standardized data form. Survival outcomes were calculated by Kaplan-Meier curves and Life-table method.
  
  
  RESULTS
  A total of 5,853 patients who met the inclusion criteria were entered into the database. The average age was 58.9±10.7 years. Males (59.5%) and adenmocarcinoma (53.0%) represented the majority of all cases. Lobectomy (87.9%) was the major operation type in practice. The 5-year overall survival rates were 81.9% for stage IA, 71.6% for IB, 55.0% for IIA, 45.2% for IIB, 34.9% for IIIA and 23.3% for IIIB (P<0.001).
  
  
  CONCLUSIONS
  This is the first and the largest clinical database for resected NSCLC in China with optimal data quality. Future collaboration to expand and share this database nationwide is warranted.
authors.affiliation: Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China; ; Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease, Guangzhou 510120, China;
authors.forename: Wenhua
authors.initials: W
authors.lastname: Liang
authors.affiliation: Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China; ; Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease, Guangzhou 510120, China;
authors.forename: Wenlong
authors.initials: W
authors.lastname: Shao
authors.affiliation: Department of Thoracic Surgery, Shanghai Pulmonary Hospital of Tongji University, Shanghai 200433, China;
authors.forename: Gening
authors.initials: G
authors.lastname: Jiang
authors.affiliation: Department of Thoracic Surgery, Shanghai Zhongshan Hospital of Fudan University, Shanghai 200032, China;
authors.forename: Qun
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Department of Cardiovascular and Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China;
authors.forename: Lunxu
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Thoracic Surgery, China and Japan Friendship Hospital, Beijing 100029, China;
authors.forename: Deruo
authors.initials: D
authors.lastname: Liu
authors.affiliation: Department of Thoracic Surgery, Shenzhen People's Hospital, Shenzhen 518020, China;
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Thoracic Oncology, Cancer Center of Sun Yat-Sen University, Guangzhou 510060, China.
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Zhu
authors.affiliation: Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China; ; Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease, Guangzhou 510120, China;
authors.forename: Jianxing
authors.initials: J
authors.lastname: He
keywords: Non-small cell lung cancer (NSCLC); database; overall survival; resected