title: Pelvic endometriosis with peritoneal fluid reduces pregnancy rates in women undergoing intrauterine insemination.
abstract: OBJECTIVE
  This study investigated the occurrence of peritoneal fluid in women undergoing intrauterine insemination (IUI) and its correlation with the stage of pelvic endometriosis and its influence on pregnancy outcomes.
  
  
  METHODS
  A retrospective case-control design was used to recruit 272 infertile women with pelvic endometriosis. The treatment protocol consisted of controlled ovarian hyperstimulation with downregulation and gonadotropin for IUI treatment following ultrasound and laparoscopic intervention. The amount and color of the peritoneal fluid were determined during laparoscopy.
  
  
  RESULTS
  The mean amount of peritoneal fluid with pelvic endometriosis that was detected using transvaginal ultrasound was ~ 15.1 mL. Women whose cycles contained more peritoneal fluid had significantly lower pregnancy rates (17.2% and 31.3%, respectively). The total clinical pregnancy rate was not significantly different between the two groups with reddish and yellowish peritoneal fluid who had pelvic endometriosis.
  
  
  CONCLUSIONS
  Pelvic endometriosis and peritoneal fluid, detected through vaginal ultrasound, have negative effects on the pregnancy outcome of IUI treatment.
authors.affiliation: Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan.
authors.forename: Hong-Ming
authors.initials: HM
authors.lastname: Wu
authors.affiliation: Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan.
authors.forename: Chii-Ruey
authors.initials: CR
authors.lastname: Tzeng
authors.affiliation: Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan.
authors.forename: Chi-Hung
authors.initials: CH
authors.lastname: Chen
authors.affiliation: Department of Obstetrics and Gynecology, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan. Electronic address: 12025@s.tmu.edu.tw.
authors.forename: Pi-Hua
authors.initials: PH
authors.lastname: Chen
mesh_terms: D000328:Adult; D001201:Ascites / Q000000981:diagnostic imaging / Q000209:etiology*; D001202:Ascitic Fluid / Q000000981:diagnostic imaging; D016022:Case-Control Studies; D003116:Color; D004715:Endometriosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D007315:Insemination, Artificial; D010388:Pelvis; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D014463:Ultrasonography
keywords: infertility; intrauterine insemination; pelvic endometriosis; peritoneal fluid; pregnancy