title: From HTS to Phase I: the Institute for Therapeutics Discovery and Development at the University of Minnesota.
abstract: The high-throughput screening core at the University of Minnesota is part of the Institute for Therapeutics Discovery and Development (ITDD), a comprehensive drug discovery and development center. The Institute provides scientific services to both academic and business communities and supports translational medicine via collaborations and contractual work. The ITDD is well-known for its broad range of screening capabilities and offers extensive medicinal chemistry expertise along with GMP scale-up and pre-clinical pharmacology support.
authors.forename: Peter I
authors.initials: PI
authors.lastname: Dosa
authors.forename: Gunda I
authors.initials: GI
authors.lastname: Georg
authors.forename: Vadim J
authors.initials: VJ
authors.lastname: Gurvich
authors.forename: Jon E
authors.initials: JE
authors.lastname: Hawkinson
authors.forename: Michael A
authors.initials: MA
authors.lastname: Walters
authors.affiliation: Institute for Therapeutics Discovery and Development, 717 Delaware St. SE, Minneapolis, MN 55414, USA. mwalters@umn.edu.
authors.forename: Henry L
authors.initials: HL
authors.lastname: Wong
mesh_terms: D002626:Chemistry, Pharmaceutical; D003299:Cooperative Behavior; D055808:Drug Discovery / Q000458:organization & administration; D057166:High-Throughput Screening Assays / Q000379:methods*; D006801:Humans; D008910:Minnesota; D009369:Neoplasms / Q000188:drug therapy; D009488:Neurosciences; D010600:Pharmacology / Q000458:organization & administration; D057170:Translational Research, Biomedical / Q000379:methods* / Q000458:organization & administration*; D014495:Universities / Q000458:organization & administration*