title: [The impact of acellular dermal matrix on complications of breast reconstruction using tissue expander/implant: a meta-analysis].
abstract: OBJECTIVE
  To analyze the effect of acellular dermal matrix (ADM) on complications of breast reconstruction using tissue expander/implant, and to offer preliminary evidences for ADM clinical application.
  
  
  METHODS
  Articles published from Jan. 2010 to Oct. 2012 were searched in Pubmed, EMbase, Science Direct and CNKI database. Literatures were filtrated according to inclusive criteria. Values were extracted from included literatures; factors regarding complications were collected. Meta-analysis was performed with Stata 12. 0.
  
  
  RESULTS
  10 researches were included. Comparing to control group, the pooled odds ratio (OR) of overall complications, infections, hematomas/seromas, explantations are 1.51(P=0.038), 1.91(P=0.032), 1.80(P=0.005) and 2.37 (P=0.138) in ADM group In breast reconstruction using tissue expander/implant, ADM increases the respectively.
  
  
  CONCLUSIONS
  occurrence of hematomas/sarcomas as well as risks of infections and overall complications.
authors.affiliation: Department of Plastic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Dong
authors.affiliation: Department of Plastic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
authors.forename: Xiao-Wei
authors.initials: XW
authors.lastname: Wu
authors.affiliation: Department of Plastic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
authors.forename: Fang-Xing
authors.initials: FX
authors.lastname: Tian
mesh_terms: D062088:Acellular Dermis; D018427:Breast Implants / Q000009:adverse effects; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000009:adverse effects* / Q000379:methods; D011183:Postoperative Complications / Q000209:etiology*; D015625:Tissue Expansion Devices / Q000009:adverse effects*