title: Blastic plasmacytoid dendritic cell neoplasm: a report of 2 cases.
abstract: Blastic plasmacytoid dendritic cell neoplasm is a recently classified aggressive hematodermic neoplasm derived from plasmacytoid dendritic cells. We describe two cases of this neoplasm, one a 15 year old child and other a 65 year male. The diagnosis was made by evaluating the detailed clinical history, morphology and flow cytometric findings. The diagnosis is rendered difficult owing to common morphological and flow cytometric overlaps. The neoplasms were characterized by skin and soft tissue involvement and strong CD4/CD56 positivity. These neoplasms are highly aggressive and have many diagnostic overlaps. Strong suspicion and detection will help in early therapeutic interventions.
authors.affiliation: OncQuest Laboratories Pvt Ltd, 3, Factory Road, New Delhi, 110029 India.
authors.forename: Raman
authors.initials: R
authors.lastname: Arora
authors.affiliation: OncQuest Laboratories Pvt Ltd, 3, Factory Road, New Delhi, 110029 India ; A 803, Plot No 7A, Navrattan Apartments, Sector 23, Dwarka, New Delhi, 110075 India.
authors.forename: Ritesh
authors.initials: R
authors.lastname: Sachdev
authors.affiliation: OncQuest Laboratories Pvt Ltd, 3, Factory Road, New Delhi, 110029 India.
authors.forename: Tribhuwan
authors.initials: T
authors.lastname: Bind
authors.affiliation: OncQuest Laboratories Pvt Ltd, 3, Factory Road, New Delhi, 110029 India.
authors.forename: Md Ateek
authors.initials: MA
authors.lastname: Khan
keywords: Dendritic; Hematodermic; Leukemia; Natural killer cell; Plasmacytoid