title: Obstructive sleep apnea syndrome and chronic kidney disease: a new cardiorenal risk factor.
abstract: Clinical and experimental studies revealed that sleep apnea might be an insidious risk factor for the progression of kidney disease and development of cardiovascular events by exacerbating well-known risk factors, namely hypertension, type 2 diabetes mellitus and obesity. Furthermore, sleep apnea also has a negative impact on endothelial function. Therefore, sleep apnea might be defined as a new cardiorenal risk factor. In this review, we aimed to summarize the evidences supporting the complex inter-relations between sleep apnea and development and progression of chronic kidney disease.
authors.affiliation: Division of Nephrology, Department of Internal Medicine and.
authors.forename: Abdullah
authors.initials: A
authors.lastname: Ozkok
authors.forename: Asiye
authors.initials: A
authors.lastname: Kanbay
authors.forename: Ali Riza
authors.initials: AR
authors.lastname: Odabas
authors.forename: Adrian
authors.initials: A
authors.lastname: Covic
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kanbay
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism; D016166:Free Radical Scavengers / Q000097:blood; D014943:Global Health; D006801:Humans; D015994:Incidence; D007249:Inflammation / Q000097:blood; D011379:Prognosis; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology; D015996:Survival Rate / Q000639:trends
chemical_list: D015415:Biomarkers; D016166:Free Radical Scavengers; D002097:C-Reactive Protein
keywords: Chronic kidney disease; hypertension; inflammation; sleep apnea