title: Regioselective synthesis of 2,3-dihydrobenzodioxepinones from epoxides and 2-bromophenols via palladium-catalyzed carbonylation.
abstract: A highly regioselective cascade synthesis of 2,3-dihydrobenzodioxepinone from 2-bromophenols and epoxides has been developed. The reactions go through nucleophilic ring-opening of epoxides and subsequent palladium-catalyzed intramolecular alkoxylcarbonylation.
authors.affiliation: Leibniz-Institut für Katalyse e.V., Albert Einstein Straße, 29a, 18059 Rostock, Germany. xiao-feng.wu@catalysis.de.
authors.forename: Haoquan
authors.initials: H
authors.lastname: Li
authors.forename: Anke
authors.initials: A
authors.lastname: Spannenberg
authors.forename: Helfried
authors.initials: H
authors.lastname: Neumann
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Wu
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D004852:Epoxy Compounds / Q000737:chemistry*; D004988:Ethers, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D010082:Oxepins / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004852:Epoxy Compounds; D004988:Ethers, Cyclic; D010082:Oxepins; D010636:Phenols; D010165:Palladium; C032038:2-bromophenol