title: Graphene oxide-enabled tandem signal amplification for sensitive SPRi immunoassay in serum.
abstract: A tandem signal amplification using bioconjugated graphene oxide and subsequent silver catalytic deposition for surface plasmon resonance imaging (SPRi) to sensitively and specifically immunoassay tumor biomarkers in serum, achieving a limit of detection down to 100 pg mL(-1) with a broad dynamic range for α-Fetoprotein (AFP) is reported.
authors.affiliation: Institute for Clean Energy & Advanced Materials, Southwest University, Chongqing, 400715, China. ecmli@swu.edu.cn.
authors.forename: Weihua
authors.initials: W
authors.lastname: Hu
authors.forename: Guangli
authors.initials: G
authors.lastname: He
authors.forename: Tao
authors.initials: T
authors.lastname: Chen
authors.forename: Chun Xian
authors.initials: CX
authors.lastname: Guo
authors.forename: Zhisong
authors.initials: Z
authors.lastname: Lu
authors.forename: Jonathan Nimal
authors.initials: JN
authors.lastname: Selvaraj
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Chang Ming
authors.initials: CM
authors.lastname: Li
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood*; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D007118:Immunoassay; D009369:Neoplasms / Q000175:diagnosis; D010087:Oxides / Q000737:chemistry; D011108:Polymers / Q000737:chemistry; D020349:Surface Plasmon Resonance; D000509:alpha-Fetoproteins / Q000032:analysis*
chemical_list: D014408:Biomarkers, Tumor; D010087:Oxides; D011108:Polymers; D000509:alpha-Fetoproteins; D006108:Graphite