title: [Modern elucidative strategies for scientific connotation of controlling toxic reactions while toxic herbs are used to the indication syndrome].
abstract: One of effective measures for controlling toxic reactions is to use toxic herbs according to corresponding indication syndrome. It is important to develop toxicity theory of Chinese medicine in a sound and international way using modern language to elucidate its scientific connotation. We expect to explain scientific connotation of controlling toxic reaction while toxic herbs are used to the indication syndrome by using holistic research ideas and methods capable of reflecting governing exterior to infer interior, establish appropriate corresponding syndrome animal models by cutting into dose-effect/toxicity of toxic Chinese herbs, construct and analyze multi-layer molecular network using theories and technologies of metabonomics, network biology, and bioinformatics.
authors.affiliation: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Tan
authors.affiliation: Faculty of Human Body Morphology, School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing 100029, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.affiliation: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Lu
authors.affiliation: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors.forename: Xiao-Juan
authors.initials: XJ
authors.lastname: He
authors.affiliation: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors.forename: Miao
authors.initials: M
authors.lastname: Jiang
authors.affiliation: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors.forename: Ai-Ping
authors.initials: AP
authors.lastname: Lu
mesh_terms: D064420:Drug-Related Side Effects and Adverse Reactions / Q000517:prevention & control*; D004365:Drugs, Chinese Herbal / Q000633:toxicity*; D008516:Medicine, Chinese Traditional / Q000379:methods*
chemical_list: D004365:Drugs, Chinese Herbal