title: The median preoptic nucleus exhibits circadian regulation and is involved in food anticipatory activity in rabbit pups.
abstract: Rabbit pups are a natural model to study food anticipatory activity (FAA). Recently, we reported that three areas in the forebrain - the organum vasculosum of lamina terminalis, median preoptic nucleus (MnPO) and medial preoptic area - exhibit activation during FAA. Here, we examined the PER1 protein profile of these three forebrain regions in both nursed and fasted subjects. We found robust PER1 oscillations in the MnPO in nursed subjects, with high PER1 levels during FAA that persisted in fasted subjects. In conclusion, our data indicate that periodic nursing is a strong signal for PER1 oscillations in MnPO and future experiments are warranted to explore the specific role of this area in FAA.
authors.affiliation: Centro de Investigaciones Biomédicas, Universidad Veracruzana , Xalapa, Veracruz , Mexico .
authors.forename: María Luisa
authors.initials: ML
authors.lastname: Moreno
authors.forename: Enrique
authors.initials: E
authors.lastname: Meza
authors.forename: Arturo
authors.initials: A
authors.lastname: Ortega
authors.forename: Mario
authors.initials: M
authors.lastname: Caba
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000833:Animals, Suckling; D059031:Anticipation, Psychological; D002940:Circadian Rhythm; D005215:Fasting; D005247:Feeding Behavior; D005260:Female; D008297:Male; D056950:Period Circadian Proteins / Q000378:metabolism; D019518:Postprandial Period; D011301:Preoptic Area / Q000378:metabolism / Q000502:physiology*; D011817:Rabbits; D015398:Signal Transduction; D013997:Time Factors
chemical_list: D056950:Period Circadian Proteins