title: Angina pectoris: current therapy and future treatment options.
abstract: Angina pectoris is the consequence of an inequality between the demand and supply of blood to the heart. Angina manifests itself as chest pain or discomfort and is a common complaint of patients in the hospital and in the clinic. There are, in fact, roughly half a million new cases of angina per year. Chest pain, while having many etiologies, is generally considered to be most lethal when related to a cardiac cause. In this review, the authors outline the current medical and surgical therapies that are used in the management of angina. Highlights of the various clinical trials that have assisted in the investigation of these therapies are summarized also. Then, the authors provide a focused review of the novel therapy options for angina that are currently being explored. From new medical treatments to revised surgical techniques to the discovery of stem cell therapy, many innovative options are being investigated for the treatment of angina.
authors.affiliation: Rush University Medical Center, 1700 W Van Buren St, Chicago, IL 60612, USA.
authors.forename: Raj
authors.initials: R
authors.lastname: Parikh
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Kadowitz
mesh_terms: D000787:Angina Pectoris / Q000503:physiopathology / Q000628:therapy*; D000818:Animals; D002317:Cardiovascular Agents / Q000494:pharmacology / Q000627:therapeutic use; D002637:Chest Pain / Q000209:etiology*; D002986:Clinical Trials as Topic; D006801:Humans; D033581:Stem Cell Transplantation / Q000379:methods*
chemical_list: D002317:Cardiovascular Agents