title: Iron oxide nanoparticle encapsulated diatoms for magnetic delivery of small molecules to tumors.
abstract: Small molecules can be co-loaded with iron oxide nanoparticles onto diatoms. With an external magnetic field, the diatoms, after systemic administration, can be attracted to tumors. This study suggests a great potential of diatoms as a novel and powerful therapeutic vehicle.
authors.affiliation: Department of Chemistry, University of Georgia, Athens, GA 30602, USA. jin.xie@uga.edu.
authors.forename: Trever
authors.initials: T
authors.lastname: Todd
authors.forename: Zipeng
authors.initials: Z
authors.lastname: Zhen
authors.forename: Wei
authors.initials: W
authors.lastname: Tang
authors.forename: Hongmin
authors.initials: H
authors.lastname: Chen
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Wang
authors.forename: Yen-Jun
authors.initials: YJ
authors.lastname: Chuang
authors.forename: Kayley
authors.initials: K
authors.lastname: Deaton
authors.forename: Zhengwei
authors.initials: Z
authors.lastname: Pan
authors.forename: Jin
authors.initials: J
authors.lastname: Xie
mesh_terms: D000818:Animals; D017377:Diatoms / Q000737:chemistry*; D016503:Drug Delivery Systems / Q000379:methods*; D005290:Ferric Compounds / Q000737:chemistry / Q000494:pharmacology; D060526:Magnetic Fields; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry*; D009374:Neoplasms, Experimental / Q000188:drug therapy* / Q000473:pathology
chemical_list: D005290:Ferric Compounds; C000499:ferric oxide