title: Comorbidity of obsessive-compulsive disorder and substance use disorder: a new heuristic.
abstract: Obsessive-compulsive disorder (OCD) and substance use disorder share several aspects of phenomenology and may be underpinned by a common mechanism with compulsivity at the core. Despite this overlap, the two disorders show a variable pattern of comorbidity. Here, we review the current evidence for comorbidity across clinical and epidemiological studies, and propose a new heuristic for substance use comorbidity in OCD, based on a hypothetical threshold of OCD severity.
authors.affiliation: Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
authors.forename: Natalie L
authors.initials: NL
authors.lastname: Cuzen
authors.forename: Dan J
authors.initials: DJ
authors.lastname: Stein
authors.forename: Christine
authors.initials: C
authors.lastname: Lochner
authors.forename: Naomi A
authors.initials: NA
authors.lastname: Fineberg
mesh_terms: D017831:Diagnosis, Dual (Psychiatry); D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000453:epidemiology* / Q000503:physiopathology; D012306:Risk; D012720:Severity of Illness Index; D019966:Substance-Related Disorders / Q000453:epidemiology* / Q000503:physiopathology
keywords: Obsessive-compulsive disorder; comorbidity; compulsivity; substance use disorder