title: [A case of liver and bone metastasis from gastrointestinal stromal tumor treated using imatinib].
abstract: A 71-year-old man with an unspecified gastric tumor had undergone gastrectomy 15 years previously, and in 2012, positron emission tomography-computed tomography(PET-CT)showed the presence of a bulky tumor located in the right hepatic liver and multiple bone metastases. Although it was unclear whether the tumor was primary or metastatic, liver biopsy was performed. Immunostaining revealed that the lesions were positive for c-kit, and therefore, these lesions were diagnosed as liver and bone metastases from gastric gastrointestinal stromal tumor(GIST). Chemotherapy with imatinib was initiated. PET-CT performed after 3 months revealed a marked decrease in fluorodeoxyglucose(FDG)accumulation. The patient is alive at present with no recurrence.
authors.affiliation: Dept. of Surgery, Osaka Rosai Hospital.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Murakami
authors.forename: Chikara
authors.initials: C
authors.lastname: Ebisui
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Okada
authors.forename: Shu
authors.initials: S
authors.lastname: Okamura
authors.forename: Kohei
authors.initials: K
authors.lastname: Murata
authors.forename: Nami
authors.initials: N
authors.lastname: Nakagomi
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Tamai
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Kinuta
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001549:Benzamides / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary; D046152:Gastrointestinal Stromal Tumors / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D000068877:Imatinib Mesylate; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D010879:Piperazines / Q000627:therapeutic use*; D049268:Positron-Emission Tomography; D011743:Pyrimidines / Q000627:therapeutic use*; D012008:Recurrence; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate