title: Aquacel surgical dressing reduces the rate of acute PJI following total joint arthroplasty: a case-control study.
abstract: An effort to prevent PJI has led to the development of antimicrobial dressings that support wound healing. We sought to determine whether Aquacel Surgical dressing independently reduces the rate of acute PJI following TJA. A single institution retrospective chart review of 903 consecutive cases who received the Aquacel Surgical dressing and 875 consecutive cases who received standard gauze dressing was conducted to determine the incidence of acute PJI (within 3 months). The incidence of acute PJI is 0.44% in the Aquacel dressing group compared to 1.7% in the standard gauze dressing group (P = 0.005). Multivariate analysis revealed that use of Aquacel dressing was an independent risk factor for reduction of PJI (odds ratio of 0.165, 95% confidence interval: 0.051-0.533). Aquacel Surgical dressing significantly reduces the incidence of acute PJI.
authors.affiliation: The Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
authors.forename: Jenny
authors.initials: J
authors.lastname: Cai
authors.affiliation: The Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Karam
authors.affiliation: The Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
authors.forename: Javad
authors.initials: J
authors.lastname: Parvizi
authors.affiliation: The Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
authors.forename: Eric B
authors.initials: EB
authors.lastname: Smith
authors.affiliation: The Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
authors.forename: Peter F
authors.initials: PF
authors.lastname: Sharkey
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage*; D019643:Arthroplasty, Replacement / Q000009:adverse effects* / Q000379:methods; D001458:Bandages; D002266:Carboxymethylcellulose Sodium / Q000008:administration & dosage*; D016022:Case-Control Studies; D006801:Humans; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000517:prevention & control*; D012189:Retrospective Studies; D014945:Wound Healing
chemical_list: D000890:Anti-Infective Agents; D002266:Carboxymethylcellulose Sodium
keywords: hip arthroplasty; knee arthroplasty; periprosthetic joint infection; wound dressing