title: Trials of biomarker-guided antimicrobial therapy in sepsis: improvements in trial design require better control groups.
authors.affiliation: Critical Care Department, D'Or Institute for Research and Education, Rio de Janeiro, Brazil, and Postgraduation Program, Instituto Nacional de Câncer, Rio de Janeiro, Brazil; Polyvalent Intensive Care Unit, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal, and Faculty of Medical Sciences, New University of Lisbon, Lisboa, Portugal.
authors.forename: Jorge I F
authors.initials: JI
authors.lastname: Salluh
authors.forename: Pedro
authors.initials: P
authors.lastname: Póvoa
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002097:C-Reactive Protein / Q000032:analysis*; D002116:Calcitonin / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D011498:Protein Precursors / Q000097:blood*; D012772:Shock, Septic / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D011498:Protein Precursors; D002116:Calcitonin; D002097:C-Reactive Protein