title: Clinical experience with insulin detemir, biphasic insulin aspart and insulin aspart in people with type 2 diabetes: Results from the Bahraini cohort of the A1chieve study.
abstract: BACKGROUND
  The A1chieve, is a multicentric (28 countries), 24-weeks, non-interventional study to evaluate the safety and effectiveness of insulin detemir, biphasic insulin aspart and insulin aspart in people with T2DM (n = 66,726) in routine clinical care across four continents.
  
  
  METHODS
  Data was collected at baseline, at 12 weeks and at 24 weeks. This short communication presents the results for patients enrolled from Manama, kingdom of Bahrain.
  
  
  RESULTS
  A total of 115 patients were enrolled in the study. Four different insulin analogue regimens were used in the study. Study patients had started on or were switched to biphasic insulin aspart (n = 67), insulin detemir (n = 16), insulin aspart (n = 4), basal insulin plus insulin aspart (n = 21) and other insulin combinations (n = 7). At baseline, glycaemic control was poor for both insulin naïve (mean HbA1c: 10.2%) and insulin users (mean HbA1c: 9.8%) groups. After 24 weeks of treatment, both the groups showed improvement in HbA1c (insulin naïve: -1.1%, insulin users: -1.3%). SADRs including major hypoglycaemic events did not occur in the study patients.
  
  
  CONCLUSIONS
  Starting or switching to insulin analogues was associated with improvement in glycaemic control with a low rate of hypoglycaemia.
authors.affiliation: Department of Endocrinology, Gulf Diabetes Center, Manama, Bahrain.
authors.forename: Wiam Ibrahim
authors.initials: WI
authors.lastname: Hussein
authors.affiliation: Department of Endocrinology, Gulf Diabetes Center, Manama, Bahrain.
authors.forename: Noha
authors.initials: N
authors.lastname: Taha
keywords: A1chieve study; Bahrain; insulin analogues; type 2 diabetes mellitus