title: Recurrence of infantile hemangioma after termination of propranolol treatment.
abstract: Propranolol has been the first-line treatment for problematic infantile hemangioma (IH) since 2008. The recurrence of IHs after stopping treatment with propranolol was reported in several studies. Mechanisms underlying this phenomenon have not been elucidated so far. Our study is the first to show the general pathology of recurrence of IH after stopping treatment with propranolol. It can provide help for the clinical treatment of IHs.
authors.affiliation: From the Department of Plastic and Reconstructive Surgery, School of Medicine, Shanghai Jiao-tong University, Shanghai Ninth People's Hospital, Shanghai, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Chang
authors.forename: Gang
authors.initials: G
authors.lastname: Ma
authors.forename: Yunbo
authors.initials: Y
authors.lastname: Jin
authors.forename: Xiaoxiao
authors.initials: X
authors.lastname: Ye
authors.forename: Yajing
authors.initials: Y
authors.lastname: Qiu
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.forename: Wenxin
authors.initials: W
authors.lastname: Yu
authors.forename: Xi
authors.initials: X
authors.lastname: Yang
authors.forename: Xiaojie
authors.initials: X
authors.lastname: Hu
authors.forename: Xiaoxi
authors.initials: X
authors.lastname: Lin
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D005260:Female; D018324:Hemangioma, Capillary / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007223:Infant; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D011433:Propranolol / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol