title: Resolution of canine ocular thelaziosis in avermectin-sensitive Border Collies from Spain.
abstract: Ocular thelaziosis by Thelazia callipaeda is an emerging disease that affects primarily dogs, but also cats, foxes and other wild carnivores, as well as humans. Three clinical cases of unilateral conjunctivitis caused by Thelazia nematodes were detected in Border Collie, a dog breed intolerant to the macrocyclic lactones. Animals came from southwestern Spain, on the border with Portugal. Eight worms were collected and identified molecularly as T. callipaeda by amplification and sequencing of partial cytochrome c oxidase subunit 1 gene. Oral treatment with mebendazole 20mg/kg (Telmin(®)) was effective in curing the infection.
authors.affiliation: Área de Parasitología, Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain. Electronic address: rcalero@unex.es.
authors.forename: Rafael
authors.initials: R
authors.lastname: Calero-Bernal
authors.affiliation: Departamento de Parasitología, Laboratorio Regional de Sanidad Animal, Servicio de Sanidad Animal, Gobierno de Extremadura, Badajoz, Spain.
authors.forename: José Marín
authors.initials: JM
authors.lastname: Sánchez-Murillo
authors.affiliation: Departamento de Patología Animal, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain.
authors.forename: Pedro María
authors.initials: PM
authors.lastname: Alarcón-Elbal
authors.affiliation: Director Técnico de Agrupación de Defensa Sanitaria Veterinaria, San Vicente de Alcántara, Badajoz, Spain.
authors.forename: José
authors.initials: J
authors.lastname: Sánchez-Moro
authors.affiliation: Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Valenzano, Bari, Italy.
authors.forename: Maria Stefanía
authors.initials: MS
authors.lastname: Latrofa
authors.affiliation: Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Valenzano, Bari, Italy; Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhães (Fiocruz-PE), Recife, Pernambuco, Brazil.
authors.forename: Filipe
authors.initials: F
authors.lastname: Dantas-Torres
authors.affiliation: Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, Valenzano, Bari, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Otranto
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D005260:Female; D008297:Male; D008463:Mebendazole / Q000494:pharmacology / Q000627:therapeutic use*; D013030:Spain; D017205:Spirurida Infections / Q000188:drug therapy / Q000662:veterinary*; D013802:Thelazioidea / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D000969:Antinematodal Agents; D008463:Mebendazole
keywords: Border Collie; Haplotype 1; Mebendazole; Spain; Thelazia callipaeda; cox1