title: Meta-analysis of self-gripping mesh (Progrip) versus sutured mesh in open inguinal hernia repair.
abstract: BACKGROUND
  This metaanalysis was designed to systematically analyse all published randomized controlled trials comparing self-gripping mesh (ProGrip) and sutured mesh to analyse early and long term outcomes for open inguinal hernia repair.
  
  
  METHODS
  A literature search was performed using the Cochrane Colorectal Cancer Group Controlled Trials Register, the Cochrane Central Register of Controlled Trials in the Cochrane Library, MEDLINE, Embase and Science Citation Index Expanded. Randomized trials comparing self-gripping mesh with sutured mesh were included. Statistical analysis was performed using Review Manager Version 5.2 software. The primary outcome measures were hernia recurrence and chronic pain after operation. Secondary outcome measures included surgical time, wound complications and perioperative complications.
  
  
  RESULTS
  Five randomized trials were identified as suitable, including 1170 patients. There was no significant difference between the two types of mesh repairs in perioperative complications, wound haematoma, chronic groin pain and hernia recurrence. Wound infection was lower in self gripping mesh group compared to sutured mesh but this was not statistically significant (risk ratio (RR) 0.57, 95% confidence interval 0.30-1.06, P = 0.08). The duration of operation was significantly shorter with self-gripping mesh compared to sutured mesh with a mean difference of -5.48 min [-9.31, -1.64] Z = 2.80 (P = 0.005).
  
  
  CONCLUSIONS
  Self-gripping mesh was associated with shorter operative time compared to sutured mesh. Both types of mesh repairs have comparable perioperative and long term outcomes.
authors.affiliation: Department of HPB Surgery, St. James Hospital, Beckett Street, Leeds LS7 1BD, United Kingdom. Electronic address: sanjay.pandanaboyana@gmail.com.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Pandanaboyana
authors.affiliation: Department of Surgery, Ninewells Hospital, Dundee DD2 5BN, United Kingdom.
authors.forename: Devender
authors.initials: D
authors.lastname: Mittapalli
authors.affiliation: Department of Surgery, Ninewells Hospital, Dundee DD2 5BN, United Kingdom.
authors.forename: Ahsan
authors.initials: A
authors.lastname: Rao
authors.affiliation: Department of HPB Surgery, St. James Hospital, Beckett Street, Leeds LS7 1BD, United Kingdom.
authors.forename: Raj
authors.initials: R
authors.lastname: Prasad
authors.affiliation: Department of HPB Surgery, St. James Hospital, Beckett Street, Leeds LS7 1BD, United Kingdom.
authors.forename: Niaz
authors.initials: N
authors.lastname: Ahmad
mesh_terms: D006552:Hernia, Inguinal / Q000601:surgery*; D059685:Herniorrhaphy / Q000379:methods*; D006801:Humans; D011474:Prosthesis Design; D013526:Surgical Mesh; D013536:Suture Techniques / Q000295:instrumentation*; D013537:Sutures
keywords: Inguinal hernia; Metaanalysis; Progrip