title: [Exposure to cadmium and plasma cortisol in workers exposed to urban stressor].
abstract: OBJECTIVE
  The aim of this study is to estimate the exposure to Cd in a group of roadmen compared to a group of drivers by environmental monitoring and biological monitoring of blood and urinary Cd. It aims to evaluate whether exposure to Cd can affect plasma cortisol.
  
  
  METHODS
  The initial sample was composed by 130 employees of Municipal Police Force (roadmen and drivers). After administration of a clinical-anamnestic questionnaire were excluded 50 subjects who presented confounding factors and 30 subjects who weren't comparable. On a final sample of 25 drivers and 25 roadmen were conducted environmental monitoring of Cd, biological monitoring of urinary and blood Cd and assessment of cortisol.
  
  
  RESULTS
  Personal exposure to Cd in air was significantly higher in roadmen compared to drivers (p = 0.015). Urinary and blood Cd were significantly increased in roadmen compared to drivers (p = 0.18 and p = 0.025). There weren't significant differences in plasma cortisol between drivers and roadmen (p> 0.05). The multiple linear regression analysis shows that urinary and blood Cd are dependent on the environment Cd levels and on the job (driver or roadmen) (p = 0.014 and p = 0.012) and plasma cortisol isn't dependent on blood and urinary Cd.
  
  
  CONCLUSIONS
  The results show a higher concentration of Cd in roadmen both in air and urine and they don't indicate an influence of exposure to low doses of Cd on plasma cortisol.
authors.affiliation: Dipartimento di Anatomia, Istologia, Medicina-Legale e Ortopedia, Unità Operativa di Medicina del Lavoro, "Sapienza" Università di Roma;
authors.forename: T
authors.initials: T
authors.lastname: Casale
authors.forename: M
authors.initials: M
authors.lastname: Ciarrocca
authors.forename: A
authors.initials: A
authors.lastname: Di Marzio
authors.forename: H A
authors.initials: HA
authors.lastname: Nieto
authors.forename: C
authors.initials: C
authors.lastname: Sacco
authors.forename: M P
authors.initials: MP
authors.lastname: Schifano
authors.forename: A
authors.initials: A
authors.lastname: Capozzella
authors.forename: M V
authors.initials: MV
authors.lastname: Rosati
authors.forename: G
authors.initials: G
authors.lastname: Tomei
authors.forename: T
authors.initials: T
authors.lastname: Caciari
authors.forename: F
authors.initials: F
authors.lastname: Tomei
mesh_terms: D000328:Adult; D001334:Automobile Driving; D002104:Cadmium; D004784:Environmental Monitoring; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D016273:Occupational Exposure; D016495:Police; D013315:Stress, Psychological; D014505:Urban Population
chemical_list: D002104:Cadmium; D006854:Hydrocortisone