title: Orbital involvement in systemic mastocytosis.
abstract: A 61-year-old female presented with a 3-day history of painful and reddened right eye with painful ocular movements. She had been diagnosed as having systemic mastocytosis 4 years earlier. Ocular examination showed Best Corrected Visual acuity of 6/6 right eye and 6/6 left eye. There was marked conjunctival injection and chemosis. The posterior segment was normal. The left eye was normal. Exophthalmometry showed 2 mm of right proptosis relative to the left eye. Computed tomography (CT) scans showed an ill-defined intra-conal lesion and enlargement of the lacrimal gland in the right orbit. A diagnostic biopsy was performed; the histopathology findings were of orbital mastocytosis. We present what our literature search suggests is the first biopsy-proven case of orbital mastocytosis.
authors.affiliation: Oculoplastic Unit, Department of Ophthalmology, Sydney Hospital and Sydney Eye Hospital , Macquarie Street, Sydney, NSW , Australia .
authors.forename: Manju
authors.initials: M
authors.lastname: Meena
authors.forename: Ross
authors.initials: R
authors.lastname: Benger
authors.forename: Irina
authors.initials: I
authors.lastname: Karnaukhvoa
authors.forename: Dale
authors.initials: D
authors.lastname: Waring
authors.forename: Yi-Chiao
authors.initials: YC
authors.lastname: Li
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D034721:Mastocytosis, Systemic / Q000150:complications*; D008875:Middle Aged; D009916:Orbital Diseases / Q000175:diagnosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014792:Visual Acuity