title: A case of vertical transmission of Chagas disease contracted via blood transfusion in Canada.
abstract: Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and is endemic in many countries in Latin America, where infected bugs of the Triatominea subfamily carry the parasite in the gut and transmit it to humans through fecal contamination of a bite. However, vertical transmission and transmission through blood transfusion and organ transplantation is well documented. Increasing immigration from endemic countries to North America has prompted blood operators, including Canadian Blood Services and Hema Quebec, to initiate blood donor testing for Chagas antibody. In the present report, an unusual case of vertical transmission from a mother, most likely infected through blood transfusion, and detected as part of a concurrent seroprevalence study in blood donors is described.
authors.affiliation: Medical, Scientific and Research Affairs, Canadian Blood Services, Toronto, Ontario;
authors.forename: Margaret A
authors.initials: MA
authors.lastname: Fearon
authors.affiliation: Medical, Scientific and Research Affairs, Canadian Blood Services, Toronto, Ontario;
authors.forename: Vito
authors.initials: V
authors.lastname: Scalia
authors.affiliation: Medical, Scientific and Research Affairs, Canadian Blood Services, Toronto, Ontario;
authors.forename: Mary
authors.initials: M
authors.lastname: Huang
authors.affiliation: Medical, Scientific and Research Affairs, Canadian Blood Services, Toronto, Ontario;
authors.forename: Irene
authors.initials: I
authors.lastname: Dines
authors.affiliation: National Reference Centre for Parasitology, McGill University, Montreal, Quebec;
authors.forename: Momar
authors.initials: M
authors.lastname: Ndao
authors.affiliation: Winnipeg Regional Health Authority Travel and Tropical Medicine Services, Winnipeg, Manitoba.
authors.forename: Philippe
authors.initials: P
authors.lastname: Lagacé-Wiens
keywords: Chagas disease; Transfusion transmission; Vertical transmission