title: Evaluation of a morphing based method to estimate muscle attachment sites of the lower extremity.
abstract: To generate subject-specific musculoskeletal models for clinical use, the location of muscle attachment sites needs to be estimated with accurate, fast and preferably automated tools. For this purpose, an automatic method was used to estimate the muscle attachment sites of the lower extremity, based on the assumption of a relation between the bone geometry and the location of muscle attachment sites. The aim of this study was to evaluate the accuracy of this morphing based method. Two cadaver dissections were performed to measure the contours of 72 muscle attachment sites on the pelvis, femur, tibia and calcaneus. The geometry of the bones including the muscle attachment sites was morphed from one cadaver to the other and vice versa. For 69% of the muscle attachment sites, the mean distance between the measured and morphed muscle attachment sites was smaller than 15 mm. Furthermore, the muscle attachment sites that had relatively large distances had shown low sensitivity to these deviations. Therefore, this morphing based method is a promising tool for estimating subject-specific muscle attachment sites in the lower extremity in a fast and automated manner.
authors.affiliation: Department of Biomechanical Engineering, University of Twente, Enschede, The Netherlands. Electronic address: pellikaan.p@gmail.com.
authors.forename: P
authors.initials: P
authors.lastname: Pellikaan
authors.affiliation: Department of Biomechanical Engineering, University of Twente, Enschede, The Netherlands; Department of Rehabilitation Medicine, Research Institute MOVE, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: M M
authors.initials: MM
authors.lastname: van der Krogt
authors.affiliation: Department of Biomechanical Engineering, University of Twente, Enschede, The Netherlands.
authors.forename: V
authors.initials: V
authors.lastname: Carbone
authors.affiliation: Department of Biomechanical Engineering, University of Twente, Enschede, The Netherlands.
authors.forename: R
authors.initials: R
authors.lastname: Fluit
authors.affiliation: Materialise N.V., Leuven, Belgium.
authors.forename: L M
authors.initials: LM
authors.lastname: Vigneron
authors.affiliation: Materialise N.V., Leuven, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: Van Deun
authors.affiliation: Department of Biomechanical Engineering, University of Twente, Enschede, The Netherlands; Orthopaedic Research Laboratory, University Medical Centre Nijmegen, The Netherlands.
authors.forename: N
authors.initials: N
authors.lastname: Verdonschot
authors.affiliation: Department of Biomechanical Engineering, University of Twente, Enschede, The Netherlands.
authors.forename: H F J M
authors.initials: HF
authors.lastname: Koopman
mesh_terms: D000369:Aged, 80 and over; D000465:Algorithms; D050281:Bones of Lower Extremity / Q000033:anatomy & histology*; D006801:Humans; D008297:Male; D008954:Models, Biological; D018482:Muscle, Skeletal / Q000033:anatomy & histology*
keywords: Bone geometry; Lower extremity; Morphing techniques; Muscle attachments; Subject-specific musculoskeletal modeling