title: Fibrosing mediastinitis mimicking sarcoidosis.
abstract: Fibrosing mediastinitis (FM), also called sclerosing mediastinitis or mediastinal fibrosis, is a rare disease characterized by excessive fibrotic reaction in the mediastinum and may compromise the airway, the great vessels and other mediastinal structures, with a morbidity directly related to the location and extent of fibrosis. The cause is not always known but is often the result of a granulomatous disease, most often the histoplasmosis. We report a 43-year-old woman with a history of tuberculosis infection 23 years ago. She attended the pulmonology clinic for cough and dyspnea. Physical examination revealed jugular venous distention at 90°. In computed tomography scan of the chest with contrast (c/c), we observed a mediastinal nodal cast provoking cava compression and obliteration of main and intermediary right lobar bronchus. The pathological examination was FM.
authors.affiliation: Medical-Surgical Unit of Respiratory Diseases, IBIS, CIBERES, University Hospital Virgen del Rocio, Seville, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Ferrer Galván
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Rodríguez Portal
authors.forename: María Pilar
authors.initials: MP
authors.lastname: Serrano Gorarredona
authors.forename: Lourdes
authors.initials: L
authors.lastname: Gómez Izquierdo
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008480:Mediastinitis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D012507:Sarcoidosis / Q000175:diagnosis*; D012598:Sclerosis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy
keywords: IgG4-related disease; fibrosing mediastinitis; sarcoidosis