title: [The research progress of biofilm and biofilm in eye disease].
abstract: Bacteria adherent on the active or inactive surface can form biofilms in which they are encased in a hydrated matrix of extracellular polymeric substances, which is so called bacterial biofilm (BBF). BBF has greater virulence and drug resistance, they can also evade the host immune system and lead to immune injury compared with planktonic bacteria. Many common medical infections involving ophthalmic infection are biofilm-associated. In this paper, the concept and biological characteristics of BBF and BBF-related ophthalmic infection were reviewed.
authors.affiliation: Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University,Beijing Ophthalmology & Visual Sciences Key Lab, Beijing 100005, China.
authors.forename: Wen-bo
authors.initials: WB
authors.lastname: Hou
authors.affiliation: Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University,Beijing Ophthalmology & Visual Sciences Key Lab, Beijing 100005, China. Email: sunxg1955@163.com.
authors.forename: Xu-guang
authors.initials: XG
authors.lastname: Sun
mesh_terms: D000818:Animals; D018441:Biofilms; D005128:Eye Diseases / Q000382:microbiology*; D006801:Humans