title: Pd-catalyzed oxidative coupling of enamides and alkynes for synthesis of substituted pyrroles.
abstract: A novel and efficient palladium(II)-catalyzed alkenyl C-H activation oxidative annulation of enamides with alkynes for the synthesis of substituted pyrroles has been developed. The reaction tolerates a wide range of functional groups and is a reliable method for the synthesis of triaryl-substituted pyrroles in high yields.
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University , Xi'an 710069, P. R. China.
authors.forename: Mi-Na
authors.initials: MN
authors.lastname: Zhao
authors.forename: Zhi-Hui
authors.initials: ZH
authors.lastname: Ren
authors.forename: Yao-Yu
authors.initials: YY
authors.lastname: Wang
authors.forename: Zheng-Hui
authors.initials: ZH
authors.lastname: Guan
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D000577:Amides; D007211:Indoles; D011758:Pyrroles; D010165:Palladium