title: Catalytic conversion of diazocarbonyl compounds to imines: applications to the synthesis of tetrahydropyrimidines and β-lactams.
abstract: The synthesis of α-carbonylimines by rhodium(II)-catalyzed reactions of α-diazoesters and organic azides has been developed and applied in hetero-Diels-Alder reactions to form highly functionalized tetrahydropyrimidines and in a one-pot, multicomponent transformation between aryldiazoacetates, p-anisyl azide, and an enonediazoacetate to produce β-lactams in high yields and diastereoselectivities.
authors.affiliation: Department of Chemistry & Biochemistry, University of Maryland , College Park, Maryland 20742, United States.
authors.forename: Michael D
authors.initials: MD
authors.lastname: Mandler
authors.forename: Phong M
authors.initials: PM
authors.lastname: Truong
authors.forename: Peter Y
authors.initials: PY
authors.lastname: Zavalij
authors.forename: Michael P
authors.initials: MP
authors.lastname: Doyle