title: New molecule for mobilizing marrow stem cells.
abstract: In this issue of Blood, Zhang et al describe an exciting new small-molecule antagonist of CXCL12-CXCR4 binding with a potent ability to mobilize hematopoietic stem cells (HSCs). Further clinical development of this new drug,Me6TREN, may have broad applications in stem-cell mobilization for cancer and in regenerative medicine.
authors.affiliation: EMORY UNIVERSITY.
authors.forename: Sakura
authors.initials: S
authors.lastname: Hosoba
authors.forename: Edmund K
authors.initials: EK
authors.lastname: Waller
mesh_terms: D000818:Animals; D005021:Ethylamines / Q000494:pharmacology*; D005786:Gene Expression Regulation; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods*; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans
chemical_list: D005021:Ethylamines; C587015:tris(2-(dimethylamino)ethyl)amine