Oral rhabdomyosarcoma: A review.
Rhabdomyosarcoma (RMS) is a rare malignant soft tissue neoplasm comprised of cells derived from the primitive mesen¬chyme. About 35% of RMS arises in the head and neck, are are classified as parameningeal and non-parameningeal forms. These are the most common soft tissue sarcoma of the children, adolescents and young adults. Their etiopathogenesis and its molecular relevance have been emphasized. The first line of treatment is radical excision and this is usually supplemented by radiotherapy. It is believed that adjunct combination chemotherapy may greatly improve the prognosis. Inadequately treated tumours grow in an infiltrative manner and recur in a high percentage of cases. Bone does not constitute an effective barrier to the growth of the tumour and bone invasion is a frequent finding in head and neck rhabdomyosarcomas. Key words:Rhabdomyosarcomas, botryoid, spindle, alveolar, sarcomas, undifferentiated.
Assistant Professor, Department of Oral Pathology & Microbiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India.
Ankita
A
Tandon
Senior Lecturer, Department of Oral Pathology & Microbiology, Indraprastha Dental, College & Hospital, New Delhi, India.
Kanika
K
Sethi
Senior Lecturer, Department of Oral Medicine & Radiology, Rungta College of Dental Sciences and Research, Kohka-Kurud Road, Bhilai-Durg, India.
Anand
A
Pratap Singh