Neurological imaging of brain damages after radiotherapy and/or chimiotherapy.
Radiotherapy and chemotherapy may induce neurological toxicities with different appearances on CT and MRI scans. While optimized radiotherapy techniques have reduced some complications, new unwanted effects have occurred on account of therapeutic protocols involving the simultaneous use of radiotherapy and chemotherapy. Advances in radio-surgery, innovative anti-angiogenic therapies, as well as prolonged patient survival have led to the emergence of new deleterious side effects. In this report, we describe the early, semi-delayed, and late encephalic complications, while specifying how to identify the morphological lesions depending on the therapeutic protocol.
Clinique Universitaire de Neuroradiologie et Imagerie, CHU de Grenoble, Grenoble, France.
A
A
Martino
Clinique Universitaire de Neuroradiologie et Imagerie, CHU de Grenoble, Grenoble, France.
A
A
Krainik
Clinique de Radiothérapie, CHU de Grenoble, Grenoble, France.
C
C
Pasteris
Clinique de Neurochirurgie, CHU de Grenoble, Grenoble, France.
D
D
Hoffmann
Clinique de Neurochirurgie, CHU de Grenoble, Grenoble, France.
S
S
Chabardes
Grenoble Institut de Neurosciences, équipe 7, 38043 Grenoble, France.
F
F
Berger
Clinique Universitaire de Neuroradiologie et Imagerie, CHU de Grenoble, Grenoble, France.
J F
JF
Le Bas
Clinique Universitaire de Neuroradiologie et Imagerie, CHU de Grenoble, Grenoble, France.
S
S
Cantin
Clinique Universitaire de Neuroradiologie et Imagerie, CHU de Grenoble, Grenoble, France.
A
A
Attye
Clinique Universitaire de Neuroradiologie et Imagerie, CHU de Grenoble, Grenoble, France. Electronic address: SGrand@chu-grenoble.fr.
S
S
Grand
D001927:Brain Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D059248:Chemoradiotherapy / Q000009:adverse effects*; D006801:Humans; D059906:Neuroimaging / Q000379:methods*; D011832:Radiation Injuries / Q000209:etiology* / Q000517:prevention & control; D016896:Treatment Outcome
Brain tumor; Chemotherapy; Radiotherapy; Toxicity