Multiyear persistence of 2 pandemic A/H1N1 influenza virus lineages in West Africa.
Our understanding of the global ecology of influenza viruses is impeded by historically low levels of viral surveillance in Africa. Increased genetic sequencing of African A/H1N1 pandemic influenza viruses during 2009-2013 revealed multiyear persistence of 2 viral lineages within West Africa, raising questions about the roles of reduced air traffic and the asynchrony of seasonal influenza epidemics among West African countries in the evolution of independent lineages. The potential for novel influenza virus lineages to evolve within Africa warrants intensified influenza surveillance in Africa and other understudied areas.
Martha I
MI
Nelson
Richard
R
Njouom
Cecile
C
Viboud
Mbayame N D
MN
Niang
Hervé
H
Kadjo
William
W
Ampofo
Adedeji
A
Adebayo
Zekiba
Z
Tarnagda
Mark A
MA
Miller
Edward C
EC
Holmes
Ousmane M
OM
Diop
D000354:Africa, Western / Q000453:epidemiology; D016000:Cluster Analysis; D005838:Genotype; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D007251:Influenza, Human / Q000453:epidemiology* / Q000635:transmission / Q000821:virology*; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D017422:Sequence Analysis, DNA
D012367:RNA, Viral