Multiple murine BRaf(V600E) melanoma cell lines with sensitivity to PLX4032.
Department of Medicine, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA; Department of Microbiology and Immunology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Molly H
MH
Jenkins
Shannon M
SM
Steinberg
Matthew P
MP
Alexander
Jan L
JL
Fisher
Marc S
MS
Ernstoff
Mary Jo
MJ
Turk
David W
DW
Mullins
Constance E
CE
Brinckerhoff
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D045744:Cell Line, Tumor; D003433:Crosses, Genetic; D005260:Female; D007211:Indoles / Q000494:pharmacology*; D020935:MAP Kinase Signaling System / Q000187:drug effects; D008297:Male; D008546:Melanoma, Experimental / Q000201:enzymology / Q000473:pathology*; D051379:Mice; D008810:Mice, Inbred C57BL; D016688:Mice, Inbred NOD; D016513:Mice, SCID; D008822:Mice, Transgenic; D020125:Mutation, Missense; D009363:Neoplasm Proteins / Q000096:biosynthesis; D009368:Neoplasm Transplantation; D017354:Point Mutation; D047428:Protein Kinase Inhibitors / Q000494:pharmacology*; D048493:Proto-Oncogene Proteins B-raf / Q000037:antagonists & inhibitors* / Q000235:genetics; D013449:Sulfonamides / Q000494:pharmacology*; D000077484:Vemurafenib
D000970:Antineoplastic Agents; D007211:Indoles; D009363:Neoplasm Proteins; D047428:Protein Kinase Inhibitors; D013449:Sulfonamides; D000077484:Vemurafenib; C482120:Braf protein, mouse; D048493:Proto-Oncogene Proteins B-raf