Extracranial orbital meningioma extending into the nasosinus in neurofibromatosis type 2.
OBJECTIVE
The purpose of this study was to report a rare case of neurofibromatosis type 2 (NF2) with extracranial orbital meningioma extending into the frontal and ethmoidal sinuses.


METHODS
This is clinical report of a 17-year-old male patient with NF2. Results of an ocular examination, computed tomography scan, and pathological findings of space-occupied orbital and nasosinus lesions are presented.


RESULTS
Computed tomography scan revealed a high-density soft tissue mass occupying the right superionasal orbit extending into the frontal and ethmoidal sinuses and bilateral acoustic schwannomas in the brain. Biopsy of the right orbital lesion demonstrated a typical meningioma as indicated with routine hematoxylin-eosin staining and immunohistochemical evaluation.


CONCLUSIONS
In this patient, an extracranial orbital meningioma, rather than optic nerve sheath meningioma extending into nasosinus, designates a diagnosis of NF2. Ophthalmologists should be aware of the possibility that patients with an extracranial orbital meningioma may also have NF2.
From the State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China.
Jianhua
J
Yan
Yongping
Y
Li
D000293:Adolescent; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis*; D008579:Meningioma / Q000175:diagnosis*; D016518:Neurofibromatosis 2 / Q000175:diagnosis*; D009669:Nose Neoplasms / Q000175:diagnosis*; D009918:Orbital Neoplasms / Q000175:diagnosis*; D010256:Paranasal Sinuses / Q000473:pathology