Akt is essential to induce NADPH-dependent NETosis and to switch the neutrophil death to apoptosis.
Lung Innate Immunity Research Laboratory, Program in Physiology and Experimental Medicine, SickKids Research Institute, The Hospital for Sick Children, Toronto, ON, Canada.
David N
DN
Douda
Lily
L
Yip
Meraj A
MA
Khan
Hartmut
H
Grasemann
Nades
N
Palaniyar
D017209:Apoptosis; D002467:Cell Nucleus / Q000378:metabolism; D015971:Gene Expression Regulation, Enzymologic; D006801:Humans; D015151:Immunoblotting; D007249:Inflammation; D008856:Microscopy, Fluorescence; D009249:NADP / Q000737:chemistry*; D009504:Neutrophils / Q000378:metabolism / Q000473:pathology*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism*; D017382:Reactive Oxygen Species
D017382:Reactive Oxygen Species; D009249:NADP; D051057:Proto-Oncogene Proteins c-akt