Sarcoidosis mimicking cancer metastasis following chemotherapy for ovarian cancer.
We report on a rare case of sarcoidosis that developed after chemotherapy for ovarian cancer, and mimicked a cancer metastasis. A 52-year-old female diagnosed with stage III ovarian cancer underwent curative surgery and postoperative chemotherapy. Four months later, her whole-body positron emission tomography and computed tomography (CT) scan showed high uptake in the mediastinal lymph nodes, and ovarian cancer recurrence was suspected. Biopsy of the mediastinal lymph nodes and subcutaneous nodules revealed noncaseating granulomas. These lesions resolved spontaneously without treatment; however, newly developed perilymphatic and centrilobular nodules were observed on follow-up chest CT. Surgical biopsy of these lesions also showed noncaseating granulomas. She was finally diagnosed with sarcoidosis.
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea. ; Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
Mi Hyun
MH
Kim
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea. ; Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
Kwangha
K
Lee
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Ki Uk
KU
Kim
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Hye-Kyung
HK
Park
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Min Ki
MK
Lee
Department of Obstetrics and Gynecology, Pusan National University School of Medicine, Busan, Korea.
Dong Soo
DS
Suh
Drug therapy; Ovarian neoplasms; Positron-emission tomography and computed tomography; Sarcoidosis