Professional differences in antigen presentation to iNKT cells.
Invariant natural killer T cells are preactivated lymphocytes that react upon recognition of CD1d-antigen complexes. Accordingly, any type of CD1d-positive cell could behave as antigen-presenting cell (APC). In this issue of Immunity, Arora et al. (2014), report that professional APCs still make the difference.
Experimental Immunology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland and Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, Singapore. Electronic address: gennaro_delibero@immunol.a-star.edu.sg.
Gennaro
G
De Libero
Experimental Immunology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland and Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, Singapore.
Lucia
L
Mori
D000818:Animals; D016207:Cytokines / Q000378:metabolism*; D003713:Dendritic Cells / Q000276:immunology*; D055611:Natural Killer T-Cells / Q000276:immunology*
D016207:Cytokines