Not like a wrecking ball: EBV fine-tunes MYC lymphomagenesis.
In this issue of Blood, Fish et al uncover how Epstein-Barr virus (EBV) enhances MYC-driven B-cell lymphoma by crossing EBV Em-EBV latent membrane protein 2A (LMP2A) transgenic mice with immunoglobulin-l (Igl)-MYC transgenic mice.
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL.
Dirk P
DP
Dittmer
D000818:Animals; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D016393:Lymphoma, B-Cell / Q000378:metabolism*; D016271:Proto-Oncogene Proteins c-myc / Q000378:metabolism*; D014763:Viral Matrix Proteins / Q000378:metabolism*
C037662:EBV-associated membrane antigen, Epstein-Barr virus; D016271:Proto-Oncogene Proteins c-myc; D014763:Viral Matrix Proteins