Acute phase protein and protein electrophoresis values for captive Grant's zebra (Equus burchelli).
Grant's zebra (Equus burchelli) are commonly kept in zoos and are subject to routine health monitoring and research studies. Recently, assays for acute phase proteins (APP) have been described in many wildlife species, and specific assays for serum amyloid A (SAA) have been well validated and studied in horses (Equus ferus caballus), in which it serves as a major APP. In the present study, serum samples from 26 Grant's zebra were subject to analysis by using assays for SAA, haptoglobin (HP), and protein electrophoresis. Reference intervals were calculated by using the robust method: SAA 1.8-31.4 mg/L and HP 0.37-1.58 mg/ml. Significant differences in SAA and HP were observed in clinically abnormal zebra; in some cases, these differences were marked and were noted in the absence of abnormal values for protein electrophoretic fractions. These data indicate that APP may be a valuable and sensitive tool in monitoring inflammation in this species.
Division of Comparative Pathology, University of Miami Miller School of Medicine, P.O. Box 016960 (R-46), Miami, FL 33101, USA. c.cray@miami.edu
Carolyn
C
Cray
Lion Country Safari, 2003 Lion Country Safari Road, Loxahatchee, FL 33470, USA.
Elizabeth
E
Hammond
Fossil Rim Wildlife Center, 2155 County Road 2008, Glen Rose, TX 76043, USA.
Holly
H
Haefele
D000209:Acute-Phase Proteins / Q000378:metabolism*; D000818:Animals; D015415:Biomarkers; D001797:Blood Protein Electrophoresis / Q000662:veterinary*; D001798:Blood Proteins / Q000378:metabolism*; D018397:Equidae / Q000097:blood* / Q000145:classification; D012016:Reference Values
D000209:Acute-Phase Proteins; D015415:Biomarkers; D001798:Blood Proteins