FDG PET/CT findings in a rare case of giant fibrovascular polyp of the esophagus harboring atypical lipomatous tumor/well-differentiated liposarcoma.
A 70-year-old man with a history of chronic lymphocytic leukemia (CLL) underwent FDG PET/CT scan, which revealed a large polypoid soft tissue lesion in the esophagus with peripheral FDG avidity. An endoscopic biopsy revealed inflammatory changes with scattered CLL cells. The final histopathology demonstrated an 18-cm long and 4-cm wide giant fibrovascular polyp that was removed in 2 pieces. The polyp was composed of atypical adipose tissue with scattered giant cells and spindle-shaped cells as well as foci of CLL. Mouse double minute 2 homolog amplification was noted by fluorescence in situ hybridization diffusely in the giant polyp consistent with well-differentiated liposarcoma in a giant fibrovascular polyp.
From the *Molecular and Imaging Therapy Service, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York; †Department of Radiology, Weill Cornell Medical Center, New York, NY; ‡Department of Radiology, Memorial Sloan-Kettering Cancer Center, Basking Ridge, NJ; §Division of Hematology/Oncology, Department of Medicine, and ¶Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY.
Volkan
V
Beylergil
Marc Z
MZ
Simmons
Gary
G
Ulaner
Joseph
J
Jurcic
Hanina
H
Hibshoosh
Jorge A
JA
Carrasquillo
D000368:Aged; D002454:Cell Differentiation; D003287:Contrast Media; D004724:Endoscopy; D004947:Esophagus / Q000000981:diagnostic imaging* / Q000473:pathology; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008067:Lipoma / Q000000981:diagnostic imaging / Q000473:pathology*; D008080:Liposarcoma / Q000473:pathology*; D008297:Male; D064847:Multimodal Imaging; D011127:Polyps / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
D003287:Contrast Media; D019788:Fluorodeoxyglucose F18