Seroprevalence of parasitic zoonoses and their relationship with social factors among the Canadian Inuit in Arctic regions.
Residents of Arctic communities are at increased risk of contracting infectious diseases transmitted by wildlife. Data collected from the International Polar Year Inuit Health Survey were used to determine the seroprevalence of 4 parasitic zoonoses in three Inuit jurisdictions of the Canadian Arctic and to assess risk factors of infection. To date, this is the most comprehensive survey of its kind. Immunoenzymatic methods were used for the detection of antibodies against Toxocara canis, Echinococcus granulosus, Trichinella sp., and Toxoplasma gondii. We determined the weighted prevalence of parasitic infections in 36 Inuit communities across the Inuvialuit settlement region, Nunavut, and Nunatsiavut. Our results indicate infrequent exposure to Toxocara and Echinococcus (1.7 and 6.3%, respectively). Exposure to T. gondii (27.2%) and Trichinella (18.6%) was more prevalent and was generally higher in Nunavut compared to other northern regions. Overall, seropositivity was related to age, education, and consumption of marine mammals and seafood.
Research Institute of the McGill University Health Centre, Montreal, Canada.
Stephanie
S
Goyette
Research Institute of the McGill University Health Centre, Montreal, Canada.
Zhirong
Z
Cao
JD MacLean Tropical Diseases Centre, Montreal General Hospital, Montreal, Canada.
Michael
M
Libman
Research Institute of the McGill University Health Centre, Montreal, Canada; National Reference Center for Parasitology, Montreal, Canada.
Momar
M
Ndao
Research Institute of the McGill University Health Centre, Montreal, Canada; National Reference Center for Parasitology, Montreal, Canada. Electronic address: brian.ward@mcgill.ca.
Brian J
BJ
Ward
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood; D000913:Antibodies, Protozoan / Q000097:blood; D001110:Arctic Regions; D002170:Canada / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010272:Parasitic Diseases / Q000453:epidemiology*; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D012959:Socioeconomic Factors; D055815:Young Adult; D015047:Zoonoses / Q000453:epidemiology*
D000909:Antibodies, Helminth; D000913:Antibodies, Protozoan
Echinococcus; Inuit; Seroepidemiologic studies; Toxocara; Toxoplasma; Trichinella