CA3 sees the big picture while dentate gyrus splits hairs.
The dentate gyrus (DG) and area CA3 of the hippocampus have been long hypothesized to perform pattern separation and pattern completion, respectively. A new study published in this issue of Neuron, Neunuebel and Knierim (2014), provides strong empirical support for this functional dissociation.
Center for Memory and Brain, Department of Psychology, Boston University, 2 Cummington Mall, Boston, MA 02215, USA. Electronic address: enewman@gmail.com.
Ehren L
EL
Newman
Center for Memory and Brain, Department of Psychology, Boston University, 2 Cummington Mall, Boston, MA 02215, USA.
Michael E
ME
Hasselmo
D000818:Animals; D001245:Association Learning / Q000502:physiology*; D056654:CA3 Region, Hippocampal / Q000502:physiology*; D018891:Dentate Gyrus / Q000502:physiology*; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology*