Multiple FDG-avid injection site granulomas due to lovenox injection.
An initial staging FDG PET/CT scan in a 15-year-old female patient with lymphoma revealed FDG-avid tumor in the mediastinum and the neck. After chemotherapy, a restaging PET/CT scan was performed. Although mediastinal and cervical lesions were not visualized, multiple new foci of activity were noted in the bilateral anterior thighs, which corresponded to soft tissue nodules in the subcutaneous tissue on the low-dose CT. On the third PET/CT study, multiple new foci appeared in the subcutaneous tissue in the anterior abdomen. Additional clinical history was obtained, indicating multiple recent subcutaneous injections of anticoagulants.
From the *Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China; and †Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Bin
B
Liu
Sherwin
S
Chan
Sabah
S
Servaes
Hongming
H
Zhuang
D000293:Adolescent; D017984:Enoxaparin / Q000008:administration & dosage* / Q000009:adverse effects*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006099:Granuloma / Q000139:chemically induced*; D006801:Humans; D007267:Injections; D008223:Lymphoma / Q000000981:diagnostic imaging; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
D017984:Enoxaparin; D019788:Fluorodeoxyglucose F18