Primary anorectal Hodgkin lymphoma: report of a case and review of the literature.
Primary colorectal lymphomas are very rare. They are mostly B-cell non-Hodgkin lymphomas. Only 2 cases of anorectal Hodgkin lymphoma have been described so far, both affecting HIV-infected males and showing Epstein-Barr virus infection. We report an unusual case of primary Hodgkin lymphoma of the anorectal region in an HIV-negative, Epstein-Barr virus-infected patient and in the absence of inflammatory bowel disease. The importance of distinguishing Hodgkin lymphoma from Epstein-Barr virus-induced lymphoproliferative disorders and from Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly is stressed in particular in non-immunocompromised patients and in the absence of history of inflammatory bowel disease.
Department of Medical Biotechnology, Section of Pathology, University of Siena, 53100, Siena, Italy. Electronic address: maradot@libero.it.
Maria Raffaella
MR
Ambrosio
Department of Medical Biotechnology, Section of Pathology, University of Siena, 53100, Siena, Italy.
Bruno Jim
BJ
Rocca
Department of Medical Biotechnology, Section of Pathology, University of Siena, 53100, Siena, Italy.
Aurora
A
Barone
Department of Medical Biotechnology, Section of Pathology, University of Siena, 53100, Siena, Italy.
Maria Grazia
MG
Mastrogiulio
Surgery Unit Valdichiana Hospital, Montepulciano, 53045, Montepulciano, Italy.
Aurelio
A
Costa
Department of Medical Biotechnology, Section of Pathology, University of Siena, 53100, Siena, Italy.
Cristiana
C
Bellan
Section of Pathology, Azienda Ospedaliera Universitaria Senese, 53100, Siena, Italy.
Stefano
S
Lazzi
D000368:Aged; D001005:Anus Neoplasms / Q000473:pathology*; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008297:Male; D012004:Rectal Neoplasms / Q000473:pathology*
Anorectal lymphoma; EBV; Hodgkin lymphoma; Immunosuppression; Large bowel tumors