Lethal factor and anti-protective antigen IgG levels associated with inhalation anthrax, Minnesota, USA.
Bacillus anthracis was identified in a 61-year-old man hospitalized in Minnesota, USA. Cooperation between the hospital and the state health agency enhanced prompt identification of the pathogen. Treatment comprising antimicrobial drugs, anthrax immune globulin, and pleural drainage led to full recovery; however, the role of passive immunization in anthrax treatment requires further evaluation.
Mark D
MD
Sprenkle
Jayne
J
Griffith
William
W
Marinelli
Anne E
AE
Boyer
Conrad P
CP
Quinn
Nicki T
NT
Pesik
Alex
A
Hoffmaster
Joseph
J
Keenan
Billie A
BA
Juni
David D
DD
Blaney
D000881:Anthrax / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology* / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000097:blood*; D000914:Antibodies, Viral / Q000097:blood*; D000942:Antigens, Bacterial / Q000097:blood*; D001408:Bacillus anthracis / Q000302:isolation & purification* / Q000472:pathogenicity; D001427:Bacterial Toxins / Q000097:blood*; D015916:Drainage, Postural; D004334:Drug Administration Schedule; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology* / Q000628:therapy; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D000914:Antibodies, Viral; D000942:Antigens, Bacterial; D001427:Bacterial Toxins; D016756:Immunoglobulins, Intravenous; C030325:anthrax toxin
Bacillus anthracis; Inhalation anthrax; Minnesota; USA; anthrax; anthrax immune globulin; anti-PA; anti-protective antigen; critical care; lethal factor; zoonoses