Colorectal carcinoma with bone metastases detected by 18F-choline PET/CT.
We report a case of metastatic colorectal carcinoma detected by F-choline PET/CT. A 72-year-old man with history of prostate cancer (previously treated with prostatectomy) underwent F-choline PET/CT for restaging. PET/CT revealed a focal area of increased F-choline uptake corresponding to a rectal nodule. Furthermore, 2 areas of increased radiopharmaceutical uptake were evident in the right clavicle and in the body of the 10th dorsal vertebra, corresponding to the osteolytic lesions. Based on these PET/CT findings, the patient underwent biopsy of the rectal nodule and left clavicular lesion. Histologic examination demonstrated the presence of a colorectal carcinoma metastatic to the bone.
From the *Department of Nuclear Medicine and PET Center, Oncology Institute of Southern Switzerland, Bellinzona; and †Institute of Pathology, Locarno, Switzerland.
Giorgio
G
Treglia
Luca
L
Ceriani
Jessica
J
Barizzi
Gaetano
G
Paone
Luca
L
Giovanella
D000368:Aged; D001706:Biopsy; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary*; D002794:Choline / Q000031:analogs & derivatives*; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D011468:Prostatectomy; D014057:Tomography, X-Ray Computed
C516370:fluoromethylcholine; D002794:Choline