Intramolecular dearomatizing [3 + 2] annulation of α-imino carbenoids with aryl rings furnishing 3,4-fused indole skeletons.
The rhodium-catalyzed dearomatizing [3 + 2] annulation reaction of 4-(3-arylpropyl)-1,2,3-triazoles is described. It provides a straightforward synthetic pathway from simple 5-aryl-1-alkynes leading to tricyclic 3,4-fused dihydroindoles via the corresponding 1,2,3-triazoles.
Department of Synthetic Chemistry and Biological Chemistry, Kyoto University , Katsura, Kyoto 615-8510, Japan.
Tomoya
T
Miura
Yuuta
Y
Funakoshi
Masahiro
M
Murakami
D002384:Catalysis; D003500:Cyclization; D007211:Indoles / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*
D007211:Indoles; C030011:carbene; C030374:indole; D012238:Rhodium; D008697:Methane