Zebra-borne equine herpesvirus type 1 (EHV-1) infection in non-African captive mammals.
Equine herpesvirus type 1 (EHV-1) was detected in an Indian rhinoceros (Rhinoceros unicornis), which was euthanized because of severe neurological disease. Encephalitis was suspected and EHV-1 DNA was detected in brain, lung, and spleen tissues. The viral IR6 protein was detected in lung tissues by Western blot analysis. Phylogenetic analyses of EHV-1 sequences amplified from various tissues was nearly identical to one recently described that resulted in both non-fatal and fatal encephalitis in polar bears. This represents transmission of EHV-1 to a species that is not naturally sympatric with the natural host of the virus and broadens the host range to Asian non-equid perissodactyls.
Leibniz-Institute for Zoo and Wildlife Research, Alfred-Kowalke-Strasse 17, 10315 Berlin, Germany.
Azza
A
Abdelgawad
Institut für Virologie, Freie Universität Berlin, Robert-von-Ostertag-Str. 7-13, 14163 Berlin, Germany; Department of Virology, Faculty of Veterinary Medicine, Zagazig University, Egypt.
Walid
W
Azab
Institut für Virologie, Freie Universität Berlin, Robert-von-Ostertag-Str. 7-13, 14163 Berlin, Germany.
Armando M
AM
Damiani
Zoo Nuremberg, Am Tiergarten 30, 90480 Nuremberg, Germany.
Katrin
K
Baumgartner
Zoo Nuremberg, Am Tiergarten 30, 90480 Nuremberg, Germany.
Hermann
H
Will
Institut für Virologie, Freie Universität Berlin, Robert-von-Ostertag-Str. 7-13, 14163 Berlin, Germany.
Nikolaus
N
Osterrieder
Leibniz-Institute for Zoo and Wildlife Research, Alfred-Kowalke-Strasse 17, 10315 Berlin, Germany. Electronic address: greenwood@izw-berlin.de.
Alex D
AD
Greenwood
D000034:Abortion, Veterinary / Q000821:virology*; D000818:Animals; D000836:Animals, Zoo / Q000821:virology*; D015153:Blotting, Western; D001921:Brain / Q000821:virology; D018397:Equidae / Q000821:virology*; D005260:Female; D005858:Germany; D006566:Herpesviridae Infections / Q000635:transmission / Q000662:veterinary* / Q000821:virology; D004861:Herpesvirus 1, Equid / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D008168:Lung / Q000821:virology; D008969:Molecular Sequence Data; D010527:Perissodactyla / Q000821:virology*; D010802:Phylogeny; D011247:Pregnancy; D014764:Viral Proteins / Q000235:genetics
D014764:Viral Proteins
EHV-1; Polar bear; Rhinoceros; Trans-species transmission; Zoo