(S)-(+)-cis-4'-Benzyl-oxypraziquantel.
The asymmetric unit of the title compound, C26H30N2O3 {systematic name (S)-(+)-2-[cis-4-(benz-yloxy)cyclo-hexa-ne-carb-on-yl]-1,2,3,6,7,11b-hexa-hydro-4H-pyrazino-[2,1-a]isoquin-olin-4-one}, consists of two independent mol-ecules in which the O= Camide group is syn to the N-C(C=Olactam) moiety, making dihedral angles of 2.0 (8) and 3.7 (8)°. The conformation of the 1,4-disubstituted cyclo-hexane ring is cis in each independent mol-ecule, with the carbonyl group occupying an equatorial position and the benz-yloxy group an axial position. In one mol-ecule, two C and one O atom of the benz-yloxy group are disordered over two sets of sites, with a refined occupancy ratio of 0.772 (8):0.228 (8). In the crystal, mol-ecules are linked by C-H⋯O inter-actions, forming ribbons parallel to the b-axis direction.
Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, 04510 México, DF, Mexico.
Alberto
A
Cedillo-Cruz
Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, 04510 México, DF, Mexico.
María Isabel
MI
Aguilar
Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, 04510 México, DF, Mexico.
Helgi
H
Jung-Cook