Introduction of rapid methicillin-resistant Staphylococcus aureus polymerase chain reaction testing and antibiotic selection among hospitalized patients with purulent skin infections.
Introduction of a rapid methicillin-resistant Staphylococcus aureus (MRSA) polymerase chain reaction assay, with physician education and pharmacist guidance, did not significantly reduce excessive empiric prescription of MRSA-active antibiotics despite the test's accuracy and potential to substantially reduce inappropriate antibiotic use.
Department of Emergency Medicine, Olive View-University of California, Los Angeles (UCLA) Medical Center, Sylmar.
Sophie
S
Terp
Anusha
A
Krishnadasan
William
W
Bowen
Julianne
J
Joo
Daniel
D
Furoy
Joseph
J
Chan
Gregory
G
Moran
David
D
Talan
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006801:Humans; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification*; D008875:Middle Aged; D016133:Polymerase Chain Reaction / Q000379:methods*; D012189:Retrospective Studies; D013207:Staphylococcal Skin Infections / Q000188:drug therapy* / Q000382:microbiology*
D000900:Anti-Bacterial Agents
MRSA; antimicrobial stewardship; molecular diagnostics; skin and soft tissue infection