[Palmoplantar keratoderma: a rare manifestation of myxoedema].
BACKGROUND
Herein we report a rare case of acquired palmoplantar keratoderma in association with myxoedema and hypothyroidism.


METHODS
A 53-year-old woman presented with palmoplantar keratoderma, dry skin, muscular weakness and cramps for 9 months. The laboratory work-up revealed autoimmune thyroiditis with hypothyroidism. Skin biopsy showed chronic eczema. Other causes of acquired palmoplantar keratoderma were ruled out. Rapid improvement was achieved within 3 weeks of institution of hormone replacement therapy.


CONCLUSIONS
Although this association is very rare, hypothyroidism must be suspected in patients with acquired palmoplantar keratoderma, particularly when it occurs in association with systemic symptoms.
Service de dermatologie-vénérologie, CHU Ibn Rochd, 1, rue des Hôpitaux, Quartier des Hôpitaux, 20360 Casablanca, Maroc. Electronic address: meriama_dr@hotmail.com.
M
M
Bouras
Service de dermatologie-vénérologie, CHU Ibn Rochd, 1, rue des Hôpitaux, Quartier des Hôpitaux, 20360 Casablanca, Maroc.
F
F
Hali
Service de dermatologie-vénérologie, CHU Ibn Rochd, 1, rue des Hôpitaux, Quartier des Hôpitaux, 20360 Casablanca, Maroc.
K
K
Khadir
Service d'endocrinologie, CHU Ibn Rochd, 1, rue des Hôpitaux, Quartier des Hôpitaux, 20360 Casablanca, Maroc.
H
H
Addi
Service d'endocrinologie, CHU Ibn Rochd, 1, rue des Hôpitaux, Quartier des Hôpitaux, 20360 Casablanca, Maroc.
A
A
Farouki
Service de dermatologie-vénérologie, CHU Ibn Rochd, 1, rue des Hôpitaux, Quartier des Hôpitaux, 20360 Casablanca, Maroc.
H
H
Benchikhi
D004485:Eczema / Q000150:complications; D004643:Emollients / Q000627:therapeutic use; D005148:Facial Dermatoses / Q000188:drug therapy / Q000209:etiology; D005221:Fatigue / Q000209:etiology; D005260:Female; D005533:Foot Dermatoses / Q000188:drug therapy / Q000209:etiology; D006229:Hand Dermatoses / Q000188:drug therapy / Q000209:etiology; D020249:Hormone Replacement Therapy; D006801:Humans; D007057:Ichthyosis / Q000188:drug therapy / Q000209:etiology; D007645:Keratoderma, Palmoplantar / Q000209:etiology*; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology; D009230:Myxedema / Q000188:drug therapy / Q000209:etiology*; D012074:Remission Induction; D013967:Thyroiditis, Autoimmune / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D013974:Thyroxine / Q000627:therapeutic use
D004643:Emollients; D013974:Thyroxine
Hypothyroidie; Hypothyroidism; Myxoedema; Myxœdème; Palmo-plantaire; Palmoplantar keratoderma