nBu4NI-catalyzed oxidative imidation of ketones with imides: synthesis of α-amino ketones.
nBu4NI-Catalyzed oxidative imidation of ketones and imides for the synthesis of α-amino ketones were realized for the first time. The methodology is characterized by its wide substrate scope even for acetone with readily available phthalimide, saccharin and succinimide, which opens a new pathway for direct imidation of ketones.
Department of Chemistry, Northeast Normal University, Changchun, 130024, China. zhangq651@nenu.edu.cn.
Yunhe
Y
Lv
Yan
Y
Li
Tao
T
Xiong
Yu
Y
Lu
Qun
Q
Liu
Qian
Q
Zhang
D002384:Catalysis; D007094:Imides / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*
D007094:Imides; D007659:Ketones; D000644:Quaternary Ammonium Compounds; C009405:tetrabutylammonium