Mycobacterial lipid logic.
During infection of the lung epithelium, Mycobacterium tuberculosis must infect and survive within macrophages long enough to be transported into deeper lung tissues. Cambier et al. (2013) show that pathogenic mycobacteria use the coordinated action of two cell wall glycolipids to regulate macrophage recruitment to initial infection sites.
Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA.
M Sloan
MS
Siegrist
Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: crb@berkeley.edu.
Carolyn R
CR
Bertozzi
D000818:Animals; D005260:Female; D057131:Immune Evasion; D008264:Macrophages / Q000382:microbiology*; D008563:Membrane Lipids / Q000378:metabolism*; D009161:Mycobacterium / Q000502:physiology*
D008563:Membrane Lipids