Internal iliac and uterine arteries Doppler ultrasound in the assessment of normotensive and chronic hypertensive pregnant women.
The objective of this work was to compare Doppler flows pulsatility index (PI) and resistance indexes (RI) of uterine and internal iliac arteries during pregnancy in low risk women and in those with stage-1 essential hypertension. From January 2010 and December 2012, a longitudinal and prospective study was carried out in 103 singleton uneventful pregnancies (72 low-risk pregnancies and 31 with stage 1 essential hypertension)at the 1(st), 2(nd) and 3(rd) trimesters. Multiple linear regression models, fitted using generalized least squares and whose errors were allowed to be correlated and/or have unequal variances, were employed; a model for the relative differences of both arteries impedance was utilized. In both groups, uterine artery PI and RI exhibited a gestational age related decreasing trend whereas internal iliac artery PI and RI increased. The model testing the hemodynamic adaptation in women with and without hypertension showed similar trend. Irrespective of blood pressure conditions, the internal iliac artery resistance pattern contrasts with the capacitance pattern of its immediate pelvic division, suggesting a pregnancy-related regulatory mechanism in the pelvic circulation.
1] Departamento de Biologia Experimental, Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal [2] IBMC-Instituto de Biologia Molecular e Celular, 4150-180 Porto, Portugal [3] Centro Hospitalar do Porto EPE, Departamento da Mulher e da Medicina Reprodutiva, Largo Prof. Abel Salazar, 4099-001 Porto, Portugal.
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Guedes-Martins
Centro Hospitalar do Porto EPE, Departamento da Mulher e da Medicina Reprodutiva, Largo Prof. Abel Salazar, 4099-001 Porto, Portugal.
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Cunha
Centro Hospitalar do Porto EPE, Departamento da Mulher e da Medicina Reprodutiva, Largo Prof. Abel Salazar, 4099-001 Porto, Portugal.
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Saraiva
1] Department of Mathematics, Faculty of Sciences of the University of Porto, Portugal [2] CMUP-Centre of Mathematics of the University of Porto, Portugal.
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Gaio
1] Departamento de Medicina, Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal [2] Centro Hospitalar S. João, 4200-319 Porto, Portugal.
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Macedo
1] Departamento de Biologia Experimental, Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal [2] IBMC-Instituto de Biologia Molecular e Celular, 4150-180 Porto, Portugal [3] Ginecologia-Obstetrícia, Hospital-CUF Porto, 4100 180 Porto, Portugal.
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Almeida
D000293:Adolescent; D000328:Adult; D001783:Blood Flow Velocity; D005260:Female; D005865:Gestational Age; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D007083:Iliac Artery / Q000000981:diagnostic imaging*; D011247:Pregnancy; D014463:Ultrasonography; D055988:Uterine Artery / Q000000981:diagnostic imaging*; D055815:Young Adult