Campylobacter coli cultured from the stools of a patient with immunoproliferative small intestinal disease.
Campylobacter has been associated with immunoproliferative small intestinal disease (IPSID), on the basis of 16S rDNA sequencing, in situ hybridization, and immunohistochemistry. Here, for the first time, we have cultured Campylobacter from the stools of a patient with IPSID. Phenotypic analysis and whole genome sequencing identified Campylobacter coli. PCR on a IPSID tissue biopsy sample was positive for Campylobacter coli and negative for Campylobacter jejuni. These findings further support a causative role for Campylobacter in the development of IPSID.
Infectious Diseases Unit, University of Caen, Caen, France.
S
S
Coeuret
A
A
de La Blanchardière
V
V
Saguet-Rysanek
S
S
Chèze
M
M
Tavernier
D
D
Arsène
A
A
Criscuolo
S
S
Brisse
M
M
Vergnaud
R
R
Verdon
M
M
Lecuit
D000328:Adult; D017000:Campylobacter coli / Q000235:genetics / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D005243:Feces / Q000382:microbiology*; D016680:Genome, Bacterial; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D007161:Immunoproliferative Small Intestinal Disease / Q000382:microbiology* / Q000473:pathology; D008297:Male; D008853:Microscopy; D049268:Positron-Emission Tomography; D011860:Radiography, Abdominal; D017422:Sequence Analysis, DNA
D004269:DNA, Bacterial
Campylobacter; IPSID; immunoproliferative small intestinal disease; lymphoma; α-Heavy-chain disease