Spindle assembly factor protection.
In this issue, Song et al. (2014) describe how microtubules and the RAN GTPase/importin-β system collaborate to control timing of HURP action and its turnover via the anaphase promoting complex (APC)-proteasome system, thereby ensuring temporal control of late mitotic events.
Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
Laura L Pontano
LL
Vaites
Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: wade_harper@hms.harvard.edu.
J Wade
JW
Harper
D006801:Humans; D008870:Microtubules / Q000502:physiology*; D008941:Spindle Apparatus / Q000378:metabolism*