Th17 cells at the crossroads of autoimmunity, inflammation, and atherosclerosis.
The connection between inflammation, autoimmunity, and atherosclerosis is long established. In this issue of Immunity, Lim et al. (2014) demonstrate that oxidized low-density lipoprotein is one of the key environmental factors driving the development of inflammatory T helper 17 cells in atherosclerosis.
Department of Biomedical Imaging, Genentech Inc., South San Francisco, CA 94080, USA. Electronic address: vbruggen@gene.com.
Nicholas
N
van Bruggen
Department of Immunology, Genentech Inc., South San Francisco, CA 94080, USA. Electronic address: ouyang@gene.com.
Wenjun
W
Ouyang
D000818:Animals; D050197:Atherosclerosis / Q000276:immunology*; D003713:Dendritic Cells / Q000276:immunology*; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology*; D020381:Interleukin-17 / Q000378:metabolism*; D058504:Th17 Cells / Q000276:immunology*
D020381:Interleukin-17