A randomized, blinded, controlled clinical study of particulate anorganic bovine bone mineral and calcium phosphosilicate putty bone substitutes for socket preservation.
OBJECTIVE
The purpose of this study was to compare the clinical efficacy of an anorganic bovine bone graft particulate to that of a calcium phosphosilicate putty alloplast for socket preservation.


METHODS
Thirty teeth were extracted from 24 patients. The sockets were debrided and received anorganic bovine bone mineral (BOV, n=12), calcium phosphosilicate putty (PUT, n=12), or no graft (CTRL, n=6). The sockets were assessed clinically and radiographically 5 months later. Eight sockets in the BOV group and nine in the PUT group received implants 5 to 6 months postgrafting. The maximum implant insertion torque (MIT) was measured as an index of primary implant stability. The data were analyzed with the Mann-Whitney test.


RESULTS
Both test groups had statistically significantly less reduction in mean ridge width (BOV: 1.39±0.57 mm; PUT: 1.26±0.41 mm) in comparison to the control group (2.53±0.59 mm). No statistically significant difference was identified between the test groups. MIT for PUT was ≤35 N/cm² (MIT grade 4) for seven of the nine implants. MIT values in the BOV group ranged from grade 1 (10 to 19 N/cm²) to grade 4, which was statistically significantly lower than for the PUT group. The overall implant success rate was 94.1% (16 of 17 implants were successful). No implants were lost in the PUT group; one implant failed in the BOV group.


CONCLUSIONS
Both tested bone substitutes can be recommended for preservation of alveolar ridge width following extraction. PUT might be more suitable for achieving primary stability for implants placed at 5 to 6 months postextraction.
Georgios A
GA
Kotsakis
Maurice
M
Salama
Vanessa
V
Chrepa
James E
JE
Hinrichs
Philippe
P
Gaillard
D000328:Adult; D000368:Aged; D000539:Alveolar Process / Q000601:surgery; D000818:Animals; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000379:methods; D002130:Calcium Phosphates / Q000627:therapeutic use*; D002417:Cattle; D003758:Dental Implantation, Endosseous / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D059351:Organ Sparing Treatments / Q000379:methods; D011859:Radiography; D017640:Silicates / Q000627:therapeutic use*; D014081:Tooth Extraction; D020390:Tooth Socket / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D019415:Torque; D014945:Wound Healing; D055815:Young Adult
D018786:Bone Substitutes; D002130:Calcium Phosphates; D017640:Silicates