Genetic alterations in childhood melanoma.
Melanoma is rare in children. However, the clinical features of the disease in this population have been well-documented through single-institution experiences and population-based analyses. Still, our understanding of the etiologic factors in children remains unclear and diagnosis of melanoma remains challenging in certain cases. This article reviews emerging evidence indicating that molecular characterization of these lesions in children may be of diagnostic and therapeutic value.
From the Division of Solid Malignancies, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.
Fariba
F
Navid