Improved synthesis and structural reassignment of MC1568: a class IIa selective HDAC inhibitor.
An improved synthesis and structural reassignment of the class IIa selective histone deacetylase (HDAC) inhibitor MC1568 are described.
Research Centre for Chemistry and Biotechnology, School of Life and Environmental Sciences, Deakin University , Waurn Ponds, Victoria, 3216, Australia.
Cassandra L
CL
Fleming
Trent D
TD
Ashton
Vidhi
V
Gaur
Sean L
SL
McGee
Frederick M
FM
Pfeffer
D056572:Histone Deacetylase Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry; D006877:Hydroxamic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
D056572:Histone Deacetylase Inhibitors; D006877:Hydroxamic Acids; C577554:MC1568; D011758:Pyrroles