A bispyrene derivative as a selective fluorescent probe for RNA.
A novel bispyrene compound was synthesized to selectively detect RNA through excimer emission "turn-on" in aqueous solution at physiological pH (7.4). The compound was used to successfully image RNA in HeLa cells.
Department of Chemistry and Nano Science, Global Top 5 Research Program, Ewha Womans University, Seoul 120-750, Korea. jyoon@ewha.ac.kr.
Yifan
Y
Liu
Eun Jin
EJ
Jun
Gyoungmi
G
Kim
Ae-Ree
AR
Lee
Joon-Hwa
JH
Lee
Juyoung
J
Yoon
D005456:Fluorescent Dyes / Q000737:chemistry / Q000494:pharmacology*; D006367:HeLa Cells; D006801:Humans; D011721:Pyrenes / Q000737:chemistry / Q000494:pharmacology*; D012313:RNA / Q000032:analysis* / Q000378:metabolism
D005456:Fluorescent Dyes; D011721:Pyrenes; D012313:RNA