Recurrent parathyroid carcinoma appearing as FDG negative but MIBI positive.
A 44-year-old woman with recurrent parathyroid carcinoma (PTC) presents with moderately elevated parathyroid hormone and ionized calcium levels. Dual-phase Tc-MIBI SPECT study of the neck and chest demonstrated 2 new foci in keeping with neoplastic seeding. A restaging whole-body F-FDG PET/CT showed no evidence of FDG uptake in the region of the MIBI-positive foci or any evidence of distant metastases. The role of F-FDG PET/CT for imaging PTC is still somewhat limited because of the rarity of this disease. We present a case highlighting a potential pitfall for FDG PET in detecting PTC.
From the Department of Nuclear Medicine, Royal Victoria Hospital, Montréal, Quebec, Canada.
Yazan Z
YZ
Alabed
Rajan
R
Rakheja
Javier A
JA
Novales-Diaz
Robert
R
Lisbona
D000328:Adult; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D037981:Neck Dissection; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000601:surgery; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D011877:Radionuclide Imaging; D017256:Technetium Tc 99m Sestamibi
D019788:Fluorodeoxyglucose F18; D017256:Technetium Tc 99m Sestamibi