[The influence of constant lightening on physiological parameters of rats homeostasis depending on time beginning of exposure].
The influence of constant lightening on biomarkers of ageing and rates of male rats aging was studied. It was revealed that the maintenance of rats in the constant lightening regime starting from the age of one month results in accelerated ageing of the organism, the reduction of the phases progressive and stable growth, early occurrence of presenile and senile periods, to the earlier occurrence of water-and-salt metabolism imbalance, accelerate the process of "aging" of the antioxidant system in comparison with the rates of the control group. On the contrary, the maintenance of rats in the constant lightening regime starting from the age of fourteen months slows ageing of the organism, increases body growth, delays appearance of pathological changes in the urine, slows down the "aging" of the enzymatic components of the antioxidant system.
T A
TA
Lotosh
I A
IA
Vinogradova
V A
VA
Iliukha
E A
EA
Khizhkin
D000375:Aging / Q000502:physiology*; D000818:Animals; D001835:Body Weight; D002374:Catalase / Q000378:metabolism; D004231:Diuresis / Q000502:physiology*; D006706:Homeostasis; D008029:Lighting; D008297:Male; D017440:Photoperiod; D051381:Rats; D013482:Superoxide Dismutase / Q000378:metabolism; D013997:Time Factors
D002374:Catalase; D013482:Superoxide Dismutase