[Pharmacoepidemiological study of the use of non-steroid antiinflamatory drugs in high-risk cardiovascular patients].
In order to determine the frequency of extended use of non-steroidal anti-inflammatory drugs (NSAID) in Colombian patients with high cardiovascular risk (HCVR), a retrospective study was developed which identified HCVR patients who used NSAID for over five continuous months from January 2011 and March 2013. Patients chronically receiving nitrates, digitalis and clopidogrel and acetylsalicylic acid (ASA), known as HCVR, were identified. An analysis of the frequencies of use based on the co-medication received was performed. Concomitant use of NSAID was found in 0,35% of consumers of nitrates (average time: 9,5 ± 4,4 months), in 0,36% of consumers of clopidogrel and ASA (average time: 9,3 ± 3,4 months), and in 0,4% of consumers of digitalis (10,2 ± 4,6 months). It is concluded that there is a low proportion of chronic use of NSAID in high-risk cardiovascular patients.
Grupo de investigación en Farmacoepidemiología y Fármacovigilancia, Universidad Tecnológica de Pereira, Pereira, Colombia.
Jorge Enrique
JE
Machado-Alba
Grupo de investigación en Farmacoepidemiología y Fármacovigilancia, Universidad Tecnológica de Pereira, Pereira, Colombia.
Verónica
V
Alzate-Carvajal
Grupo de investigación en Farmacoepidemiología y Fármacovigilancia, Universidad Tecnológica de Pereira, Pereira, Colombia.
Luis
L
Echeverri-Cataño
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D004363:Drug Utilization / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017891:Pharmacoepidemiology; D012189:Retrospective Studies; D018570:Risk Assessment; D013997:Time Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal