Personal DNA donation to energize genomic medicine.
Immense strides toward improved human genomic sequencing have been made over the past decade, but significant obstacles to clinical research and translation are now evident. Novel approaches able to traverse financial, regulatory, and ethical obstacles on behalf of patients and the public health are needed. We propose a novel approach to the collection and annotation of personal genomic data using an organized donation program analogous to the national organ-procurement system.
1] Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA [2] Indiana Institute for Personalized Medicine, Indianapolis, Indiana, USA.
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1] Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA [2] Indiana Institute for Personalized Medicine, Indianapolis, Indiana, USA.
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D035843:Biomedical Research / Q000331:legislation & jurisprudence / Q000379:methods / Q000458:organization & administration; D003219:Confidentiality / Q000331:legislation & jurisprudence; D004247:DNA / Q000235:genetics*; D030561:Databases, Nucleic Acid / Q000331:legislation & jurisprudence / Q000458:organization & administration; D057286:Electronic Health Records / Q000458:organization & administration; D015894:Genome, Human; D023281:Genomics / Q000331:legislation & jurisprudence / Q000379:methods*; D006801:Humans; D018802:Patient-Centered Care / Q000379:methods; D009927:Tissue and Organ Procurement / Q000331:legislation & jurisprudence / Q000458:organization & administration*; D014481:United States
D004247:DNA