Acaricidal activity of petroleum ether extracts from Eupatorium adenophorum against the ectoparasitic cattle mite, Chorioptes texanus.
In this study, we evaluated the acaricidal efficacy of extracts obtained from the plant Eupatorium adenophorum against the common cattle mite Chorioptes texanus. The results showed that 95% ethanol extracts at concentrations of 1.0, 0.5, and 0.25 g/mL (w/v) were highly toxic to C. texanus in vitro, killing 100% of mites in 4 h. Similarly, petroleum ether extracts of E. adenophorum resulted in between 80 and 100% mortality of mites in vitro at concentrations of 0.1, 0.05, and 0.025 mL/mL (v/v) within 4 h. In clinical trials, all infected individuals completely recovered after two treatments administered at 7-day intervals and remained disease-free at 60 days posttreatment. The clinical effect of treatment with E. adenophorum petroleum ether extracts was similar to that of treatment with the acaricide fenvalerate. These results indicated that E. adenophorum contains novel potential acaricidal compounds that can effectively control mites in livestock.
Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Ya'an, 625014, Sichuan, China.
Xiang
X
Nong
Shu-Hua
SH
Li
Jia-Hai
JH
Wang
Yue
Y
Xie
Feng-Zheng
FZ
Chen
Tian-Fei
TF
Liu
Ran
R
He
Xiao-Bin
XB
Gu
Xue-Rong
XR
Peng
Guang-You
GY
Yang
D056810:Acaricides / Q000494:pharmacology* / Q000627:therapeutic use; D036603:Ageratina / Q000737:chemistry; D000473:Alkanes; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000469:parasitology / Q000517:prevention & control*; D005260:Female; D008297:Male; D008924:Mite Infestations / Q000517:prevention & control* / Q000662:veterinary; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D040042:Psoroptidae / Q000187:drug effects*; D012997:Solvents
D056810:Acaricides; D000473:Alkanes; D010936:Plant Extracts; D012997:Solvents; C004544:naphtha