Invasive fungal sinusitis in a healthy athlete due to long-term anabolic steroid use.
Invasive fungal rhinosinusitis is a potentially fatal infection that affects immunocompromised patients. Prognosis is generally poor despite aggressive medical and surgical treatments. We present the first reported case of invasive fungal sinusitis in a healthy 18-year-old male athlete who was taking anabolic androgenic steroids (AAS). The effects of excessive AAS use on the immune system are not fully understood, but there may be consequences at supraphysiological concentrations. This case demonstrates potential immunomodulatory effects of anabolic steroids and highlights a previously unknown cause of invasive fungal sinusitis.
Department of Head & Neck Surgery, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, California, U.S.A.
Irene A
IA
Kim
Christopher F
CF
Thompson
Paul A
PA
Kedeshian
Fernando
F
Palma-Diaz
Jeffrey D
JD
Suh
D000293:Adolescent; D045930:Anabolic Agents / Q000009:adverse effects*; D000728:Androgens / Q000009:adverse effects*; D001228:Aspergillosis / Q000139:chemically induced*; D001232:Aspergillus fumigatus; D056352:Athletes; D006801:Humans; D008297:Male; D012852:Sinusitis / Q000382:microbiology*; D013256:Steroids / Q000009:adverse effects*; D013997:Time Factors
D045930:Anabolic Agents; D000728:Androgens; D013256:Steroids
Aspergillus; Invasive fungal sinusitis; anabolic; aspergillosis; sinus; steroids; surgery