Corneal biomechanical characteristics in children with diabetes mellitus.
To compare the corneal biomechanical properties in children with type 1 diabetes mellitus (DM) and healthy children. In this cross-sectional study, the study and control groups were composed of 68 children with DM and 74 healthy children, respectively. The corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg) and corneal-compensated intraocular pressure (IOPcc) were measured with the ocular response analyzer (ORA). Associations between ocular and diabetic parameters were also evaluated. There were no statistically significant differences between the two groups in age or gender distribution. The mean CH was 10.8 ± 1.5 and 10.7 ± 1.7 mmHg while the mean CRF was 10.9 ± 1.9 and 10.5 ± 1.6 mmHg in the diabetic group and control group, respectively. The mean IOPg was 15.9 ± 3.7 and 15.2 ± 3.4 mmHg, and the mean IOPcc was 15.8 ± 3.0 and 15.3 ± 3.4 mmHg in the diabetic and control group, respectively. There were no statistically significant differences between the two groups for CH, CRF, IOPg, and IOPcc measurements (independent t test, p = 0.624, p = 0.207, p = 0.263, p = 0.395, respectively). This study shows that type 1 DM does not have any effect on the corneal biomechanical parameters in childhood.
Department of Pediatric Opthalmology, Dr Sami Ulus Children's Health and Disease Training and Research Hospital, Babur Street No: 44, Altindag, Ankara, 06080, Turkey, drpinarnalcaci@yahoo.com.
Pınar
P
Nalcacioglu-Yuksekkaya
Emine
E
Sen
Semra
S
Cetinkaya
Veysel
V
Bas
Zehra
Z
Aycan
Faruk
F
Ozturk
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D001696:Biomechanical Phenomena / Q000502:physiology; D016022:Case-Control Studies; D002648:Child; D003430:Cross-Sectional Studies; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D012044:Regression Analysis; D017678:Sex Distribution; D055815:Young Adult