Factors associated with Hypokalemia in Continuous Ambulatory Peritoneal Dialysis Patients.
Hypokalemia is a frequent problem in patients on continuous ambulatory peritoneal dialysis (CAPD) and is affected by multiple factors. To evaluate factors associated with hypokalemia, we studied 68 patients on maintenance CAPD treatment for at least six months. In univariate analysis, patients with hypokalemia were associated with older age and the presence of diabetes mellitus. Serum albumin, calcium-phosphate product, triglyceride, body mass index, protein nitrogen appearance, and lean body mass assessed by creatinine kinetics were significantly lower as compared to those without hypokalemia. Serum C-reactive protein was significantly higher in the patients with hypokalemia. Multivariate stepwise linear regression analysis revealed that the serum albumin level and the ultrafiltration volume at the peritoneal equilibration test were independent factors associated with hypokalemia. This suggests that the serum potassium level may be an important nutritional marker in CAPD patients. Further longitudinal investigation is needed to clarify this relationship.
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Hyun-Wook
HW
Kim
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Jae Hyun
JH
Chang
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Sun Young
SY
Park
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Sung Jin
SJ
Moon
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Dong Ki
DK
Kim
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Jung Eun
JE
Lee
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Seung Hyeok
SH
Han
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Beum Seok
BS
Kim
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Shin-Wook
SW
Kang
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Kyu Hun
KH
Choi
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Ho Young
HY
Lee
Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Yonsei University, Seoul, Korea.
Dae-Suk
DS
Han
Continuous ambulatory peritoneal dialysis; Hypokalemia; Nutritional status; Potassium