[Age-related clinical and laboratory features of patients with occluded main arteries of lower extremities].
The study of clinical and laboratory features of patients with occluded main arteries of lower extremities included morphological characteristics of peripheral blood platelets in patients of different age in the acute period of the disease and after surgical treatment. The results were subjected to correlation analysis versus standard hemostatic parameters. Mean cell volume and enhanced anisocytosis proved the most informative morphological indicators. The mean platelet volume was increased in all patients before and after surgery especially in the elder age group. It reflected persistent activation of thrombocytopoiesis as confirmed by the studies of hemostasis. Therefore, these parameters may be used for additional testing in diagnostics of the risk of ischemic complications and repeated thrombosis. The timely prescription of auxiliary corrective therapy increases effectiveness of the treatment and the quality of life in the patients with occluded main arteries of lower extremities.
R N
RN
Shishina
T A
TA
Pchelintseva
D000328:Adult; D000368:Aged; D000375:Aging; D001157:Arterial Occlusive Diseases / Q000097:blood / Q000503:physiopathology*; D001777:Blood Coagulation / Q000502:physiology*; D001792:Blood Platelets / Q000378:metabolism*; D018450:Disease Progression; D005263:Femoral Artery / Q000503:physiopathology; D005500:Follow-Up Studies; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011788:Quality of Life; D016909:Tibial Arteries / Q000503:physiopathology*; D014664:Vasodilation / Q000502:physiology*