Twenty years of renal transplantation in children.
Two hundred and sixty-eight renal transplant operations were done in 244 children over the past 20 years. The donors were parents in 229 cases, living relatives in another 1 3 eases, and cadavers in the remaining 26 cases. There were 242 first grafts, 22 second grafts, and 4 third grafts. The initial 130 grafts were carried out with conventional immunosuppressive regimens and the subsequent 1 38 were done using immunosuppression including cyclosporin-A. In January 1995, 186 recipients (76.2%) were alive with functioning grafts, 33 (1 3.5%) were alive on dialyses, and 25 (10.2%) were dead. The management results in terms of patient and graft survival, as well as the causes of graft failure and patient death are described.
A
A
Hasegawa
T
T
Kawamura
K
K
Hoshinaga
O
O
Ogawa
S
S
Shishido
H
H
Nakai
A
A
Aikawa
T
T
Ohara
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006084:Graft Rejection / Q000188:drug therapy / Q000401:mortality*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007223:Infant; D007564:Japan / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000401:mortality* / Q000601:surgery* / Q000628:therapy; D016030:Kidney Transplantation / Q000401:mortality*; D019520:Living Donors; D008297:Male; D006435:Renal Dialysis; D015996:Survival Rate; D014019:Tissue Donors
D007166:Immunosuppressive Agents