Atypical esthesioneuroblastoma invading oral cavity: a case report and review of the literature.
Esthesioneuroblastoma is an uncommon tumour of neuroectodermal origin. The authors describe a rare presentation of an atypical esthesioneuroblastoma invading oral cavity. The clinical presentation, aetiology, diagnosis, and management of this condition are discussed. The patient developed significant swelling in the right anterosuperior alveolar mucosa and had moderate tooth mobility. Conventional x-rays and computed tomography revealed a large osteolytic lesion, with imprecise limits. Histological findings along with immunohistochemical staining results and clinical features led to the diagnosis of high-grade esthesioneuroblastoma. Local recurrences and neck metastasis were detected. The rare oral findings produced delayed in diagnosis which may lead to a compromise in planning and execution of further radical management and thus a poor prognosis.
The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1168853011139286.
Department of Pathology, Federal University of Espírito Santo, Piratininga n,180/602, Praia da Costa, Vila Velha - ES, 29101-220 Vitória, Brazil. sandra.zeidler@ufes.br.
Sandra Ventorin
SV
von Zeidler
Rafaela
R
Guidi
Rita de Cássia Gonçalves
Rde C
Alencar
Renato
R
Aguiar
Elismauro Francisco
EF
Mendonça
Aline Carvalho
AC
Batista
Rejane Faria
RF
Ribeiro-Rotta
D018304:Esthesioneuroblastoma, Olfactory / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D009055:Mouth / Q000473:pathology; D009296:Nasal Cavity / Q000000981:diagnostic imaging / Q000473:pathology*; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009669:Nose Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography; D055815:Young Adult