A non-joint tissue biphasic synovial sarcoma in a dog.
A subcutaneous tumour was identified in the malar region of a 14-year-old neutered female mixed breed dog. The dog was humanely destroyed and necropsy examination was performed. The tumour did not invade neighbouring tissues and no metastasis was found. Microscopically, the tumour showed a range of features including the presence of multinucleated giant cells, chondrocyte differentiation and cystic or slit-like structures. All of these features are consistent with previously reported descriptions of synovial sarcomas in dogs. Mesenchymal cells accounted for the majority of the tumour, but cytokeratin-positive epithelioid components were also confirmed by immunohistochemistry. The tumour was diagnosed as a biphasic type of synovial sarcoma. Synovial sarcoma in man may develop in tissues unrelated to joints and this is the first report of a non-joint synovial sarcoma in a dog.
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, Tokyo, Japan.
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Takimoto
Laboratory of Veterinary Toxicology, Tokyo University of Agriculture and Technology, Tokyo, Japan. Electronic address: kzsuzuki@cc.tuat.ac.jp.
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Suzuki
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, Tokyo, Japan.
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Ogawa
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, Tokyo, Japan.
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Segawa
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, Tokyo, Japan.
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Hara
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, Tokyo, Japan; Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.
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Itahashi
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, Tokyo, Japan; Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.
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Kimura
Laboratory of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo, Japan.
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Iwasaki
Laboratory of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo, Japan.
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Nishifuji
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, Tokyo, Japan.
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Shibutani
D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D008339:Mandibular Neoplasms / Q000473:pathology / Q000662:veterinary*; D013584:Sarcoma, Synovial / Q000473:pathology / Q000662:veterinary*
biphasic tumour; dog; immunohistochemistry; synovial sarcoma