Effect of dietary selenomethionine on growth performance, tissue burden, and histopathology in green and white sturgeon.
A comparative examination of potential differences in selenium (Se) sensitivity was conducted on two sturgeon species indigenous to the San Francisco Bay-Delta. Juvenile green (Acipenser medirostris), recently given a federally threatened status, and white sturgeon (Acipenser transmontanus) were exposed to one of four nominal concentrations of dietary l-selenomethionine (SeMet) (0 (control), 50, 100, or 200 mg SeMet/kg diet) for 8 weeks. Mortality, growth performance, whole body composition, histopathology, and Se burdens of the whole body, liver, kidneys, gills, heart, and white muscle were determined every 2 to 4 weeks. Significant (p<0.05) mortality was observed in green sturgeon fed the highest SeMet diet after 2 weeks, whereas no mortality was observed in white sturgeon. Growth rates were significantly reduced in both species; however, green sturgeon was more adversely affected by the treatment. Dietary SeMet significantly affected whole body composition and most noticeably, in the decline of lipid contents in green sturgeon. Selenium accumulated significantly in all tissues relative to the control groups. After 4 and 8 weeks of exposure, marked abnormalities were observed in the kidneys and liver of both sturgeon species; however, green sturgeon was more susceptible to SeMet than white sturgeon at all dietary SeMet levels. Our results showed that a dietary Se concentration at 19.7 ± 0.6 mg Se/kg, which is in range with the reported Se concentrations of the benthic macro-vertebrate community of the San Francisco Bay, had adverse effects on both sturgeon species. However, the exposure had a more severe pathological effect on green sturgeon, suggesting that when implementing conservation measures, this federally listed threatened species should be monitored and managed independently from white sturgeon.
Department of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.
Nicola
N
De Riu
Department of Animal Science, University of California, One Shields Avenue, Davis, CA 95616-8521, USA.
Jang-Won
JW
Lee
Department of Animal Science, University of California, One Shields Avenue, Davis, CA 95616-8521, USA.
Susie S Y
SS
Huang
Department of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.
Giuseppe
G
Moniello
Department of Animal Science, University of California, One Shields Avenue, Davis, CA 95616-8521, USA. Electronic address: sshung@ucdavis.edu.
Silas S O
SS
Hung
D000818:Animals; D001823:Body Composition / Q000187:drug effects; D004032:Diet; D005399:Fishes; D048788:Growth and Development / Q000187:drug effects*; D007668:Kidney / Q000737:chemistry / Q000187:drug effects; D008099:Liver / Q000737:chemistry / Q000187:drug effects; D009026:Mortality; D012643:Selenium / Q000032:analysis; D012645:Selenomethionine / Q000032:analysis / Q000378:metabolism / Q000633:toxicity*; D014018:Tissue Distribution; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000378:metabolism / Q000633:toxicity*
D014874:Water Pollutants, Chemical; D012645:Selenomethionine; D012643:Selenium
Green and white sturgeon; Growth performance; Histopathology; Selenium toxicity; Selenomethionine; Tissue burden