Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy.
An NMR method is reported that allows diastereomeric ratios to be determined even in crowded spectra or where chemical shift differences are small compared to multiplet widths. Band-selective pure shift NMR collapses multiplets to singlets, greatly improving spectral resolution while largely retaining, or even enhancing, signal-to-noise ratio.
School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK. g.a.morris@manchester.ac.uk.
Ralph W
RW
Adams
Liam
L
Byrne
Péter
P
Király
Mohammadali
M
Foroozandeh
Liladhar
L
Paudel
Mathias
M
Nilsson
Jonathan
J
Clayden
Gareth A
GA
Morris
D006569:Hesperidin / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
D006569:Hesperidin