Biomechanical analysis of four- versus six-screw constructs for short-segment pedicle screw and rod instrumentation of unstable thoracolumbar fractures.
BACKGROUND
Conventionally, short-segment fusion involves instrumentation of one healthy vertebra above and below the injured vertebra, skipping the injured level. This short-segment construct places less surgical burden on the patient compared with long-segment constructs, but is less stable biomechanically, and thus has resulted in clinical failures. The addition of two screws placed in the fractured vertebral body represents an attempt to improve the construct stiffness without sacrificing the benefits of short-segment fusion.


OBJECTIVE
To determine the biomechanical differences between four- and six-screw short-segment constructs for the operative management of an unstable L1 fracture.


METHODS
Biomechanical study of instrumentation in vertebral body cadaveric models simulating an L1 axial load injury pattern.


METHODS
Thirteen intact spinal segments from T12 to L2 were prepared from fresh-frozen cadaver spines. An axial load fracture of at least 50% vertebral body height was produced at L1 and then instrumented with pedicle screws. Specimens were evaluated in terms of construct stiffness, motion, and rod strain. Two conditions were tested: a four-screw construct with no screws at the L1 fractured body (4S) and a six-screw construct with screws at all levels (6S). The two groups were compared statistically by paired Student t test.


RESULTS
The mean stiffness in flexion-extension was increased 31% (p<.03) with the addition of the two pedicle screws in L1. Relative motion in terms of vertical and axial rotations was not significantly different between the two groups. The L1-L2 rod strain was significantly increased in the six-screw construct compared with the four-screw construct (p<.001).


CONCLUSIONS
In a cadaveric L1 axial load fracture model, a six-screw construct with screws in the fractured level is more rigid than a four-screw construct that skips the injured vertebral body.
Department of Orthopaedic Surgery, University of Miami Miller School of Medicine, PO Box 016960 (D-27), Miami, FL 33101, USA.
Robert P
RP
Norton
Max Biedermann Institute for Biomechanics, Mount Sinai Medical Center, Department of Research, 4300 Alton Road, Miami Beach, FL 33140, USA.
Edward L
EL
Milne
Max Biedermann Institute for Biomechanics, Mount Sinai Medical Center, Department of Research, 4300 Alton Road, Miami Beach, FL 33140, USA.
David N
DN
Kaimrajh
Department of Orthopaedic Surgery, University of Miami Miller School of Medicine, PO Box 016960 (D-27), Miami, FL 33101, USA.
Frank J
FJ
Eismont
Department of Orthopaedic Surgery, University of Miami Miller School of Medicine, PO Box 016960 (D-27), Miami, FL 33101, USA; Max Biedermann Institute for Biomechanics, Mount Sinai Medical Center, Department of Research, 4300 Alton Road, Miami Beach, FL 33140, USA.
Loren L
LL
Latta
Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, UWMF Centennial Building, 1685 Highland Avenue, Madison, WI, 53705-2281, USA. Electronic address: swilliams@ortho.wisc.edu.
Seth K
SK
Williams
D000328:Adult; D001696:Biomechanical Phenomena / Q000502:physiology; D006801:Humans; D008159:Lumbar Vertebrae / Q000293:injuries / Q000503:physiopathology / Q000601:surgery*; D008875:Middle Aged; D065289:Pedicle Screws; D016059:Range of Motion, Articular / Q000502:physiology*; D016103:Spinal Fractures / Q000503:physiopathology / Q000601:surgery*; D013123:Spinal Fusion / Q000295:instrumentation*; D013904:Thoracic Vertebrae / Q000293:injuries / Q000503:physiopathology / Q000601:surgery*; D055815:Young Adult
Axial load fracture; Pedicle screw instrumentation; Short-segment fusion; Spine fracture biomechanics; Spine fracture fixation; Thoracolumbar instrumentation