Gas diffusion as a new fluidic unit operation for centrifugal microfluidic platforms.
A centrifugal microfluidic platform prototype with an integrated membrane for gas diffusion is presented for the first time. The centrifugal platform allows multiple and parallel analysis on a single disk and integrates at least ten independent microfluidic subunits, which allow both calibration and sample determination. It is constructed with a polymeric substrate material and it is designed to perform colorimetric determinations by the use of a simple miniaturized optical detection system. The determination of three different analytes, sulfur dioxide, nitrite and carbon dioxide, is carried out as a proof of concept of a versatile microfluidic system for the determination of analytes which involve a gas diffusion separation step during the analytical procedure.
Sensors & Biosensors Group (GSB), Department of Chemistry, Universitat Autònoma de Barcelona, Edifici Cn, Bellaterra, Catalonia, 08193, Spain. julian.alonso@uab.es.
Oriol
O
Ymbern
Natàlia
N
Sández
Antonio
A
Calvo-López
Mar
M
Puyol
Julian
J
Alonso-Chamarro
D002245:Carbon Dioxide / Q000032:analysis / Q000302:isolation & purification; D002498:Centrifugation; D004058:Diffusion; D005740:Gases / Q000737:chemistry* / Q000302:isolation & purification; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D008904:Miniaturization; D009573:Nitrites / Q000032:analysis / Q000302:isolation & purification; D013458:Sulfur Dioxide / Q000032:analysis / Q000302:isolation & purification
D005740:Gases; D009573:Nitrites; D013458:Sulfur Dioxide; D002245:Carbon Dioxide