Physicians' influence on breast cancer patient compliance.
In recent years there have been major advances in the treatment of breast cancer. However, taking the prescribed medication for a sufficient period of time is crucial to the success of any therapy. Thus far, no database-based studies have been published in German-speaking countries empirically examining the influence of the physician on the compliance of patients. The aim of this study is to investigate, quantify, and critically discuss the effect treating physicians have on the compliance of their breast cancer patients. Patients with a confirmed breast cancer diagnosis who started therapy (tamoxifen or aromatase inhibitors) between January 2001 and December 2011 were selected from the representative IMS Disease Analyzer database and analyzed with regard to their compliance. Practices were grouped into two categories concerning the compliance of all treated patients. A regression model showed that a breast cancer patient who is treated in a practice with a trend toward poor compliance has a nearly 60% higher risk for treatment discontinuation than would be the case in a practice with good compliance. It shows how important it is to motivate physicians to strive toward good compliance rates.
IMS Health, Frankfurt, Germany.
Karel
K
Kostev
Hochschule Fresenius, Fachbereich Wirtschaft & Medien, Idstein, Germany.
Lilia
L
Waehlert
Hochschule Fresenius, Fachbereich Wirtschaft & Medien, Idstein, Germany.
Achim
A
Jockwig
Gynäkologische Praxis, Oberursel, Germany.
Barbara
B
Jockwig
Philipps-Universität, Klinik für Gynäkologie, Endokrinologie und Onkologie, Marburg, Germany.
Peyman
P
Hadji
D000970:Antineoplastic Agents / Q000627:therapeutic use; D047072:Aromatase Inhibitors / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000453:epidemiology*; D016208:Databases, Factual; D005260:Female; D005858:Germany / Q000453:epidemiology; D006176:Gynecology / Q000706:statistics & numerical data; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D010353:Patient Education as Topic / Q000706:statistics & numerical data*; D010817:Physician-Patient Relations; D010818:Practice Patterns, Physicians'; D015995:Prevalence; D011320:Primary Health Care / Q000706:statistics & numerical data; D013629:Tamoxifen / Q000627:therapeutic use*; D016896:Treatment Outcome; D016903:Drug Monitoring
D000970:Antineoplastic Agents; D047072:Aromatase Inhibitors; D013629:Tamoxifen
Disease Analyzer; breast cancer; compliance; persistence