[Peripheral arterial disease and cardiovascular risk factors among patients infected with human immunodeficiency virus: a comparison between hospital out-patients and patients in a prison].
BACKGROUND
Cardiovascular disease among human immunodeficiency virus (HIV) infected patients is more frequent than in the general population. Peripheral arterial disease measured by ankle-brachial index (ABI) and cardiovascular risk factors (CVRF) is not well known in all groups of HIV-infected patients.


METHODS
Transversal study of HIV-infected patients >45 years, seen as outpatients in hospital (HO) in 2008 and patients institutionalized in a prison in 2009. Cardiovascular risk factors, information on the HIV infection and healthy lifestyles were evaluated. ABI was measured at rest and was considered pathological when a value ≤ 0.9 or ≥ 1.3 was obtained.


RESULTS
We included 71 patients (mean age of 50.6 ± 6.9 years, 86% male), 32 HO and 39 in prison. The most prevalent CVRF was smoking (80.2%) followed by an altered lipid profile (63.3%). The evolution time of HIV infection was 13.1 ± 7.1 years. 74.6% of patients didn't follow a heart-healthy diet and 25% were sedentary. The ABI was low in 7 cases (9.8%) and ≥ 1.3 in one. Patients in prison were younger, the rate of smokers and of individuals with low HDL were higher, the time of evolution of the HIV infections was longer and they were less adherent to a heart-healthy diet than in HO, reaching in all cases statistical significance (P<.05).


CONCLUSIONS
In our study there is a high prevalence of altered ABI. The most common CVRF is smoking, followed by the alteration of lipids. Patients in prison are more likely to be smokers, to have low HDL and they are less adherence to a heart-healthy diet.
Medicina Interna, Hospital de Terrassa, Terrassa, Barcelona, España. Electronic address: mmauri@cst.cat.
Marta
M
Mauri Pont
Medicina Interna, Hospital de Terrassa, Terrassa, Barcelona, España.
Rosa Maria
RM
Borrallo Almansa
Instituciones penitenciarias, Centro Penitenciario Brians I, Sant Esteve Sesrovires, Barcelona, España.
Guido
G
Almada Rivas
Medicina Interna, Hospital de Terrassa, Terrassa, Barcelona, España.
Miriam
M
Carbó Díez
Medicina Interna, Hospital de Terrassa, Terrassa, Barcelona, España.
Rosa
R
Solé Arnau
Medicina Interna, Hospital de Terrassa, Terrassa, Barcelona, España.
Enric
E
García Restoy
D000328:Adult; D000367:Age Factors; D055109:Ankle Brachial Index; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D008076:Cholesterol, HDL / Q000097:blood; D003430:Cross-Sectional Studies; D004032:Diet; D005260:Female; D015658:HIV Infections / Q000453:epidemiology*; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D010045:Outpatients / Q000706:statistics & numerical data; D058729:Peripheral Arterial Disease / Q000453:epidemiology*; D015995:Prevalence; D011329:Prisoners / Q000706:statistics & numerical data*; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D013997:Time Factors
D008076:Cholesterol, HDL
Ankle-brachial index; Cardiovascular risk; Human immunodeficiency virus; Prisión; Prison; Riesgo cardiovascular; Virus de la inmunodeficiencia humana; Índice tobillo-brazo