[Diffuse large B-cell lymphoma with intravascular involvement of neoplastic CD5-positive cells].
A 77-year-old man was admitted because of fever. A small number of large CD20-positive neoplastic cells were seen in the bone marrow specimen. Clinical symptoms improved with oral prednisolone. After 11 months, abdominal CT scan revealed a liver mass. The biopsy specimen from the liver mass showed diffuse infiltration of large CD20-positive neoplastic cells. The patient was diagnosed as having diffuse large B-cell lymphoma. It was of particular interest that only neoplastic B cells within small blood vessels in the liver mass were positive for CD5. The patient died of lymphoma three months after diagnosis.
Department of Internal Medicine, Okanami General Hospital.
Nobuyoshi
N
Matsuoka
Naoko
N
Sano
Takashi
T
Murayama
Kenji
K
Ueda
Hideya
H
Hashimoto
Tatsu
T
Inoki
Yoshifumi
Y
Hirokawa
Motoko
M
Yamaguchi
Naoyuki
N
Katayama
D000368:Aged; D001706:Biopsy; D001808:Blood Vessels / Q000473:pathology*; D001853:Bone Marrow / Q000473:pathology*; D018956:CD5 Antigens / Q000378:metabolism*; D006801:Humans; D008113:Liver Neoplasms / Q000378:metabolism / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000378:metabolism / Q000473:pathology*; D008297:Male
D018956:CD5 Antigens