[Component-resolved diagnosis is a new era in clinical allergology].
The paper describes the fundamentals and benefits of a new allergy diagnostic technique based on recent advances in molecular biology and biotechnology. Component-resolved diagnosis allows IgE antibodies against purified molecules (individual allergen components) to be revealed. Microanalysis is made using microarrays with applied molecules (allergen components) obtained in a recombinant fashion or extracted from natural raw materials. The authors present a current classification of animal and plant allergens and show the value of component-resolved diagnosis in clinical practice, by using specific clinical examples.
M A
MA
Mokronosova
E S
ES
Korovkina
D000485:Allergens / Q000032:analysis* / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000276:immunology; D007073:Immunoglobulin E / Q000032:analysis* / Q000276:immunology; D040081:Protein Array Analysis / Q000379:methods
D000485:Allergens; D007073:Immunoglobulin E