Efficacy of endoscopic gastroduodenal stenting for gastric outlet obstruction due to unresectable advanced gastric cancer: a prospective multicenter study.
OBJECTIVE
Gastroduodenal stents for gastric outlet obstruction due to unresectable advanced gastric cancer are increasingly used; however, their effects have not been fully evaluated.


METHODS
A multicenter prospective observational study was performed. Patients were eligible if they had stage IV gastric cancer with a gastric outlet obstruction scoring system (GOOSS) score of 0 (no oral intake) or 1 (liquids only). Self-expandable metallic stents were delivered endoscopically. The effects of stents were evaluated.


RESULTS
Twenty patients were enrolled and 18 were eligible (15 men, three women; median age, 70 years). Stent placement was successfully performed in all patients, with no complications. After stenting, a GOOSS score of 2 (soft solids only) or 3 (low-residue or full diet) was achieved in 13 (72%) patients. An improvement in the GOOSS score by one or more points was obtained in 16 (94%) patients. The median duration of fasting and hospital stay was 3 (range, 0-9) days and 18 (6-168) days, respectively. Chemotherapy was performed after stenting in 13 (72%) patients.


CONCLUSIONS
Gastroduodenal stents are thought to be feasible, safe, and effective for gastric outlet obstruction due to unresectable advanced gastric cancer, with rapid clinical relief and a short hospital stay.
Department of Gastroenterological Surgery, Higashiosaka City General Hospital, Osaka, Japan.
Shunji
S
Endo
Shuji
S
Takiguchi
Yasuhiro
Y
Miyazaki
Kazuhiro
K
Nishikawa
Hiroshi
H
Imamura
Ko
K
Takachi
Yutaka
Y
Kimura
Atsushi
A
Takeno
Shigeyuki
S
Tamura
Masaki
M
Mori
Yuichiro
Y
Doki
D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004867:Equipment Design; D005260:Female; D017219:Gastric Outlet Obstruction / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009752:Nutritional Status; D010166:Palliative Care / Q000379:methods; D011446:Prospective Studies; D012709:Serum Albumin / Q000378:metabolism; D015607:Stents; D013274:Stomach Neoplasms / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
D012709:Serum Albumin
gastric outlet obstruction; stent; stomach neoplasms