Gas chromatography-mass spectrometry determination of earthy-musty odorous compounds in waters by two phase hollow-fiber liquid-phase microextraction using polyvinylidene fluoride fibers.
A rapid and sensitive method for the determination of earthy-musty odorous compounds, 2-methylisoborneol, 2-isopropyl-3-methoxy pyrazine, 2,4,6-trichloroanisole, 2,3,6-trichloroanisole, and geosmin, in water samples has been developed. The method was based on coupling a new polyvinylidene fluoride (PVDF) hollow-fiber liquid-phase microextraction system with gas chromatography-mass spectrometry (GC-MS). The PVDF hollow fibers have high porosity and an enhanced solvent compatibility for extraction of the target analytes. Experimental conditions were optimized by investigating the type of extraction solvent, sample pH, sodium chloride concentration, stirring speed, extraction time, and GC-MS conditions. Under optimized conditions, the earthy-musty odorous compounds exhibited good linearity (R>0.995) in the concentration range of 6.2-250ng/L. The repeatability and reproducibility of the method were lower than 6.8% and 9.8%, respectively. The limit of detection and limit of quantification values were lower than 2.0 and 6.2ng/L, respectively. The analysis of different water samples such as tap, pond, rive and waste water indicated minimal matrix effects. Analyte recoveries for real samples spiked at different concentrations were between 84.4% and 117.5%.
Center for Disease Prevention and Control of Guangdong Province, Guangzhou 511430, China. Electronic address: shengbingyu@sina.com.
Shengbing
S
Yu
School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Qin
Q
Xiao
Center for Disease Prevention and Control of Guangdong Province, Guangzhou 511430, China.
Binghui
B
Zhu
Center for Disease Prevention and Control of Guangdong Province, Guangzhou 511430, China.
Xiuhua
X
Zhong
Center for Disease Prevention and Control of Guangdong Province, Guangzhou 511430, China.
Yinghua
Y
Xu
Center for Disease Prevention and Control of Guangdong Province, Guangzhou 511430, China.
Guangning
G
Su
Center for Disease Prevention and Control of Guangdong Province, Guangzhou 511430, China.
Min
M
Chen
D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D059627:Liquid Phase Microextraction / Q000379:methods*; D009812:Odorants / Q000032:analysis*; D011145:Polyvinyls / Q000737:chemistry*; D015203:Reproducibility of Results; D012965:Sodium Chloride / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D014867:Water / Q000737:chemistry; D005465:Fluorocarbon Polymers
D011145:Polyvinyls; D012965:Sodium Chloride; D012997:Solvents; D014867:Water; C024865:polyvinylidene fluoride; D005465:Fluorocarbon Polymers
Gas chromatography–mass spectrometry; Hollow-fiber liquid-phase microextraction; Odorous compounds; Polyvinylidene fluoride; Waters