Diabesity: palliating, curing or preventing the dysmetabolic diathesis.
This opinionated evidence-based selective review addresses flawed concepts related to "obesity", bariatric surgery and approaches to treatment and prevention of a dysmetabolic syndrome of overnutrition and underactivity from the perspective of developmental origins of diseases prevalent in mid-life and beyond. Innovations focus on methods affecting appetite regulation and energy expenditure applicable throughout the life-cycle on the individual level but with transgenerational population-wide implications. Readers can expect new knowledge and enhanced understanding of a global health problem: "diabesity".
Department of Surgery, SUNY Downstate Medical Center, Brooklyn, NY, USA; Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY, USA. Electronic address: jkral@downstate.edu.
John G
JG
Kral
D001069:Appetite Regulation; D050110:Bariatric Surgery; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology / Q000517:prevention & control; D004198:Disease Susceptibility; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D024821:Metabolic Syndrome / Q000209:etiology / Q000517:prevention & control / Q000628:therapy; D009765:Obesity / Q000209:etiology / Q000517:prevention & control / Q000601:surgery*; D011247:Pregnancy
BMI; Gastric banding; Gastric bypass; Gestational diabetes mellitus; Metabolic syndrome