Synthesis of functionalized polycyclic aromatic compounds via a formal [2 + 2]-cycloaddition.
A base-promoted formal [2 + 2]-cycloaddition of 2-acyl-2'-vinyl-1,1'-biaryls was developed to provide polycyclic cyclobutanols as a step toward the synthesis of substituted polycyclic aromatic hydrocarbons and their heterocyclic analogues.
Graduate School of Pharmaceutical Sciences, Kyoto University , Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.
Yuuki
Y
Nagamoto
Yousuke
Y
Yamaoka
Shun
S
Fujimura
Yoshiji
Y
Takemoto
Kiyosei
K
Takasu
D061565:Cycloaddition Reaction; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011084:Polycyclic Aromatic Hydrocarbons / Q000138:chemical synthesis* / Q000737:chemistry
D006571:Heterocyclic Compounds; D011084:Polycyclic Aromatic Hydrocarbons