[Information and consent in dental care associated with biomedical research].
BACKGROUND
Tooth extraction as a part of dental care provides an opportunity to obtain dental pulp stem cells that could constitute new therapeutic tools for craniofacial bone and teeth repair. However, the use of tooth as a biological sample of human origin must comply with legislation and ethical rules.


METHODS
A systematic literature review was conducted using Medline, Réseau Rodin, EM-Premium, Légifrance, and the Comité consultatif national d'éthique and Comité national odontologique d'éthique websites.


RESULTS
A total of 32 articles were included. This review of the literature on ethical issues identified the principles allowing research to be conducted in the context of dental care, while respecting the patient's autonomy and dignity.


CONCLUSIONS
The patient must receive clear and accurate information and must give his/her consent before using a tooth for research purposes. However, a number of problems remain unresolved. This study explains how patient information and consent in the context of biomedical research must remain an integral part of dental care based on an ethical relationship.
Alix
A
Le Breton
Christian
C
Hervé
Philippe
P
Pirnay
D018865:Dental Research; D006801:Humans; D007258:Informed Consent; D035842:Research Subjects