Chronic granulomatous disease presenting with salmonella brain abscesses.
Chronic granulomatous disease is a rare primary immunodeficiency caused by phagocytic cell defect. We describe the case of 43-month-old boy with chronic granulomatous disease presenting with Salmonella spp brain abscesses, together with a review of the 13 cases reported in the literature.
From the *Unit of Immunology and Infectious Diseases, University-Hospital Pediatric Department; †Unit of Radiology, Bambino Gesù Children Hospital, IRCCS; ‡Department of Public Health and Cellular Biology, Tor Vergata University, Rome; and §Pediatric Immunohematology and Bone Marrow Transplant Unit and San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), HS Raffaele Scientific Institute, Milan, Italy.
Andrea
A
Finocchi
Alessia
A
Claps
Jessica
J
Serafinelli
Irene
I
Salfa
Daniela
D
Longo
Gigliola
G
Di Matteo
Alessandro
A
Aiuti
Paolo
P
Rossi
D001922:Brain Abscess / Q000150:complications* / Q000382:microbiology / Q000473:pathology*; D002675:Child, Preschool; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D008297:Male; D012475:Salmonella / Q000302:isolation & purification*; D012480:Salmonella Infections / Q000382:microbiology / Q000473:pathology*