Formation of multiple conduit aneurysms following Matrix P conduit implantation in a boy with tetralogy of Fallot and pulmonary atresia.
We report on a 6-year old boy with tetralogy of Fallot and pulmonary atresia in whom a 16 m Matrix P conduit was implanted between the pulmonary artery and the right ventricle at the age of 16 months. Five years later he developed severe stenosis of the distal conduit anastomosis. The notable findings were several aneurysms of the conduit proximal to the distal stenosis within the high-pressure region. The wall of the aneurysms contained xenogeneic conduit tissue without inflammatory or foreign-body response. We believe that aneurysm formation of the conduit was a result of fatigue of the conduit wall under suprasystemic pressure.
Department of Paediatric Cardiology and Intensive Care Medicine, Georg-August-University Hospital Göttingen, University of Göttingen, Göttingen, Germany david.backhoff@med.uni-goettingen.de.
David
D
Backhoff
Department of Paediatric Cardiology and Intensive Care Medicine, Georg-August-University Hospital Göttingen, University of Göttingen, Göttingen, Germany.
Michael
M
Steinmetz
Department of Paediatric Cardiology and Intensive Care Medicine, Georg-August-University Hospital Göttingen, University of Göttingen, Göttingen, Germany.
Matthias
M
Sigler
Department of Paediatric Cardiology and Intensive Care Medicine, Georg-August-University Hospital Göttingen, University of Göttingen, Göttingen, Germany.
Heike
H
Schneider
D000783:Aneurysm / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D001705:Bioprosthesis / Q000009:adverse effects*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D002648:Child; D003251:Constriction, Pathologic / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D018633:Pulmonary Atresia / Q000601:surgery*; D013771:Tetralogy of Fallot / Q000601:surgery*
Aneurysm; Decellularized porcine conduit; Matrix P® conduit; Tetralogy of Fallot