Cardiac macrophages: how to mend a broken heart.
A study by Epelman et al. (2014) in this issue of Immunity demonstrates that diverse subpopulations of macrophages reside in the adult heart and can be maintained by multiple mechanisms involving both local proliferation and contributions from monocytes.
Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA.
Heather B
HB
Cohen
Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA. Electronic address: dmosser@umd.edu.
David M
DM
Mosser
D000818:Animals; D008264:Macrophages / Q000276:immunology*; D009000:Monocytes / Q000502:physiology*; D009205:Myocarditis / Q000276:immunology*; D009206:Myocardium / Q000276:immunology*