InterProScan 5: genome-scale protein function classification.
Robust large-scale sequence analysis is a major challenge in modern genomic science, where biologists are frequently trying to characterize many millions of sequences. Here, we describe a new Java-based architecture for the widely used protein function prediction software package InterProScan. Developments include improvements and additions to the outputs of the software and the complete reimplementation of the software framework, resulting in a flexible and stable system that is able to use both multiprocessor machines and/or conventional clusters to achieve scalable distributed data analysis. InterProScan is freely available for download from the EMBl-EBI FTP site and the open source code is hosted at Google Code.
European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton CB10 1SD and Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK.
Philip
P
Jones
David
D
Binns
Hsin-Yu
HY
Chang
Matthew
M
Fraser
Weizhong
W
Li
Craig
C
McAnulla
Hamish
H
McWilliam
John
J
Maslen
Alex
A
Mitchell
Gift
G
Nuka
Sebastien
S
Pesseat
Antony F
AF
Quinn
Amaia
A
Sangrador-Vegas
Maxim
M
Scheremetjew
Siew-Yit
SY
Yong
Rodrigo
R
Lopez
Sarah
S
Hunter
D017360:Arabidopsis / Q000737:chemistry / Q000235:genetics; D016000:Cluster Analysis; D016678:Genome; D023281:Genomics / Q000379:methods*; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D011381:Programming Languages; D011506:Proteins / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D012984:Software
D011506:Proteins