Copper-catalyzed double C-S bonds formation via different paths: synthesis of benzothiazoles from N-benzyl-2-iodoaniline and potassium sulfide.
A new, highly efficient procedure for the synthesis of benzothiazoles from easily available N-benzyl-2-iodoaniline and potassium sulfide has been developed. The results show copper-catalyzed double C-S bond formation via a traditional cross-coupling reaction and an oxidative cross-coupling reaction.
National & Local Joint Engineering Laboratory for New Petro-chemical Materials and Fine Utilization of Resources, Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, Ministry of Education, Hunan Normal University , Changsha, Hunan 410081, China.
Xiaoyun
X
Zhang
Weilan
W
Zeng
Yuan
Y
Yang
Hui
H
Huang
Yun
Y
Liang
D000814:Aniline Compounds / Q000737:chemistry*; D052160:Benzothiazoles / Q000138:chemical synthesis / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D010084:Oxidation-Reduction; D011188:Potassium / Q000737:chemistry*; D013440:Sulfides / Q000737:chemistry*
D000814:Aniline Compounds; D052160:Benzothiazoles; C000590474:N-benzyl-2-iodoaniline; D013440:Sulfides; D003300:Copper; D011188:Potassium