Initial success rate of percutaneous coronary intervention for chronic total occlusion in a native coronary artery is decreased in patients who underwent previous coronary artery bypass graft surgery.
OBJECTIVE
This study sought to compare the initial success rate of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) in a native coronary artery (NCA) in patients with and without previous coronary artery bypass grafting (CABG) and to assess predictive factors.


BACKGROUND
Landmark novel wiring techniques for CTO-PCI have contributed to improvement in the initial success of CTO-PCI. However, challenges persist in CTO-PCI in NCA in pCABG patients.


METHODS
Patients who underwent CTO-PCI in an NCA were selected and classified into 2 groups: pCABG (206 PCIs in 153 patients) and nCABG (1,431 PCIs in 1,139 patients).


RESULTS
CTO was located more often in the left anterior descending artery (p = 0.0003), and severe calcified lesions were observed more frequently in the pCABG group (p < 0.0001). Although the retrograde attempt was tried more frequently in the pCABG group, the CTO-PCI success rate was significantly lower in the pCABG patients than in the nCABG patients (71% vs. 83%). Longer procedural time and greater radiation exposure were needed in the pCABG patients. Logistic regression analysis among the pCABG patients revealed that intravascular ultrasound use and parallel wiring were positive factors, and lesion tortuosity was a negative factor.


CONCLUSIONS
The initial success rate of CTO-PCI of an NCA in the pCABG group was significantly decreased compared with that in the nCABG group. Anatomic complexity and unstable hemodynamic state were unfavorable conditions. This study reveals that the issues to be overcome are lying with CTO revascularization in an NCA in pCABG patients.
Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Aichi, Japan. Electronic address: tomo.tera@gmail.com.
Tomohiko
T
Teramoto
Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Aichi, Japan.
Etsuo
E
Tsuchikane
Department of Cardiovascular Medicine, Gifu Heart Center, Gifu, Japan.
Hitoshi
H
Matsuo
Department of Cardiovascular Medicine, Nagoya Heart Center, Nagoya, Aichi, Japan.
Yoriyasu
Y
Suzuki
Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Aichi, Japan.
Tsuyoshi
T
Ito
Department of Cardiovascular Medicine, Nagoya Heart Center, Nagoya, Aichi, Japan.
Tatsuya
T
Ito
Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Aichi, Japan.
Maoto
M
Habara
Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Aichi, Japan.
Kenya
K
Nasu
Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Aichi, Japan.
Masashi
M
Kimura
Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Aichi, Japan.
Yoshihisa
Y
Kinoshita
Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Aichi, Japan.
Mitsuyasu
M
Terashima
Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Aichi, Japan.
Yasushi
Y
Asakura
Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Aichi, Japan.
Tetsuo
T
Matsubara
Department of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Aichi, Japan.
Takahiko
T
Suzuki
D000368:Aged; D002908:Chronic Disease; D017023:Coronary Angiography; D001026:Coronary Artery Bypass / Q000009:adverse effects; D054059:Coronary Occlusion / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects; D011829:Radiation Dosage; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional
CART; CI; CTO; IVUS; MACE; MI; NCA; OR; PCI; TIMI; Thrombolysis In Myocardial Infarction; chronic total occlusion; confidence interval; controlled antegrade and retrograde subintimal tracking; coronary artery bypass grafting; intravascular ultrasound; major adverse cardiac event(s); myocardial infarction; nCABG; native coronary artery; no previous coronary artery bypass grafting; odds ratio; pCABG; percutaneous coronary intervention; previous coronary artery bypass grafting; retrograde approach