Dual diagnosis: rheumatoid arthritis and multiple sclerosis.
Juvenile rheumatoid arthritis (JRA) is the most common rheumatologic disease in children. Moreover, multiple sclerosis (MS) is the most frequent demyelinating disease and has been associated with various chronic inflammatory diseases. However, its association with JRA has not been frequently described. Autoimmunity in both JRA and MS has been documented in the scientific literature, although there has been no definitive finding that patients with JRA are prone to the development of MS. An increasing frequency of MS resulting from an increased use of antitumor necrosis factor agents in the treatment of rheumatoid arthritis and other chronic inflammatory diseases has been reported recently. In this study, we report on the development of MS in a patient with JRA who did not have a history of antitumor necrosis factor use.
Medical School of Duzce University, Department of Physical Medicine and Rehabilitation, Duzce, Turkey(∗). Electronic address: drozsahin@hotmail.com.
Mustafa
M
Ozsahin
Department of Neurology, Medical School of Duzce University, Duzce, Turkey(†).
Suber
S
Dikici
Department of Neurology, Bezmi Alem Vakif University, Istanbul, Turkey(‡).
Gülsen
G
Kocaman
Department of Radiology, Medical School of Duzce University, Duzce, Turkey(§).
Fahri Halit
FH
Besir
Department of Family Medicine, Medical School of Duzce University, Duzce, Turkey(¶).
Davut
D
Baltaci
Department of Physical Medicine and Rehabilitation, Medical School of Duzce University, Duzce, Turkey(‖).
Safinaz
S
Ataoglu
D000328:Adult; D001171:Arthritis, Juvenile / Q000150:complications* / Q000175:diagnosis; D001842:Bone and Bones / Q000000981:diagnostic imaging; D001921:Brain / Q000473:pathology; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D006987:Hypesthesia / Q000188:drug therapy / Q000209:etiology; D007155:Immunologic Factors / Q000627:therapeutic use; D016899:Interferon-beta / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use; D009103:Multiple Sclerosis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D018908:Muscle Weakness / Q000188:drug therapy / Q000209:etiology; D011859:Radiography
D005938:Glucocorticoids; D007155:Immunologic Factors; D016899:Interferon-beta; D008775:Methylprednisolone