Treatment of hyperglycaemia in diabetic ketoacidosis: natura non facit saltus.
In the treatment of severe diabetic ketoacidosis the gradual correction of glucose, electrolyte and fluid derangements is of utmost importance. In this paper the authors provide practical recommendations for these corrections based on novel pathophysiological insights.
Department of Intensive Care, VU Medical Center, Amsterdam, the Netherlands.
A M E
AM
Spoelstra-de Man
P
P
van der Heiden
J J
JJ
Spijkstra
A T W M
AT
Verheijen
A J
AJ
Kooter
D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism*; D016883:Diabetic Ketoacidosis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D005440:Fluid Therapy / Q000379:methods*; D006801:Humans; D006943:Hyperglycemia / Q000628:therapy; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*; D008875:Middle Aged; D009994:Osmolar Concentration; D012965:Sodium Chloride / Q000627:therapeutic use; D014883:Water-Electrolyte Imbalance / Q000209:etiology / Q000517:prevention & control / Q000628:therapy
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin; D012965:Sodium Chloride