Cycloserine induced mania.
We report a 21-year-old male who developed manic symptoms after addition of second line anti-tuberculosis treatment for his multidrug resistant tuberculosis. We identified cycloserine as offending drug; and discuss the management and possible neurobiological mechanisms as etiological explanation and implications of manic switch caused by cycloserine.
Department of Psychiatry, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Ajay Kumar
AK
Bakhla
DNB Trainee, Department of Medicine, Tata Motors Hospital, Jamshedpur, Jharkhand, India.
Prakash S
PS
Gore
Consultant, Department of Medicine, Tata Motors Hospital, Jamshedpur, Jharkhand, India.
Sanjay Lal
SL
Srivastava
Cycloserine; mania; psychosis