Pineal gland involvement in Erdheim-Chester disease detected on (18)F-FDG PET-CT imaging: a case report and review of literature.
Erdheim-Chester disease (ECD) is a rare non-Langerhan's cell histiocytosis affecting multiple organ systems. The most common systemic manifestations are bone lesions, infiltration of the pituitary stalk sometimes leading to diabetes insipidus, pulmonary fibrosis, cardiac failure and exophthalmus. Neurological symptoms as the first clinical manifestations of ECD have been reported in less than one third of cases. We report a rare presentation of a patient of ECD on 18F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography-computed tomography which revealed abnormal (18)F-FDG accumulation in the region of pineal gland, pericardium and bilateral distal tibiae.
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Anirban
A
Mukherjee
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Varun Singh
VS
Dhull
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Sellam
S
Karunanithi
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Punit
P
Sharma
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Prashant
P
Durgapal
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India. Electronic address: rkphulia@yahoo.com.
Rakesh
R
Kumar
D020790:Diabetes Insipidus, Neurogenic / Q000150:complications; D031249:Erdheim-Chester Disease / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008875:Middle Aged; D010870:Pineal Gland / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D035583:Rare Diseases / Q000150:complications / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
(18)F-FDG; Erdheim-Chester disease (ECD); PET-CT; Pineal gland