The FIP1L1-PDGFRA fusion gene and the KIT D816V mutation are coexisting in a small subset of myeloid/lymphoid neoplasms with eosinophilia.
Departement für Pathologie, Universitätsklinikum Freiburg, Freiburg, Germany.
Annette Hildegard
AH
Schmitt-Graeff
Philipp
P
Erben
Juliane
J
Schwaab
Beate
B
Vollmer-Kary
Georgia
G
Metzgeroth
Karl
K
Sotlar
Hans-Peter
HP
Horny
Hans-H
HH
Kreipe
Paul
P
Fisch
Andreas
A
Reiter
D001706:Biopsy; D001854:Bone Marrow Cells / Q000166:cytology; D018801:CD2 Antigens / Q000378:metabolism; D004802:Eosinophilia / Q000378:metabolism*; D017353:Gene Deletion; D005786:Gene Expression Regulation; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000378:metabolism*; D053645:Interleukin-2 Receptor alpha Subunit / Q000378:metabolism; D007938:Leukemia; D015470:Leukemia, Myeloid, Acute / Q000378:metabolism; D009154:Mutation; D015514:Oncogene Proteins, Fusion / Q000378:metabolism*; D016133:Polymerase Chain Reaction; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000378:metabolism; D019009:Proto-Oncogene Proteins c-kit / Q000235:genetics* / Q000378:metabolism; D020796:Receptor, Platelet-Derived Growth Factor alpha / Q000378:metabolism*; D023981:Sarcoma, Myeloid / Q000378:metabolism; D053802:Tryptases / Q000378:metabolism; D039221:mRNA Cleavage and Polyadenylation Factors / Q000378:metabolism*
D018801:CD2 Antigens; C479818:FIP1L1 protein, human; D053645:Interleukin-2 Receptor alpha Subunit; D015514:Oncogene Proteins, Fusion; D039221:mRNA Cleavage and Polyadenylation Factors; D019009:Proto-Oncogene Proteins c-kit; D020796:Receptor, Platelet-Derived Growth Factor alpha; D053802:Tryptases