Analysis of a single hemodialysis on phosphate removal of the internal fistula patients by mathematical and statistical methods.
Chronic kidney disease related mineral and bone disease (CKD-MBD) is a worldwide challenge in hemodialysis patients. In china, the number of dialysis patients is growing but few data are available about their bone disorders. In the current study, we aimed to evaluate the effect of clinical factors on the serum phosphorus clearance in the 80 maintenance hemodialysis (MHD) patients. Six clinical factors were identified for their association with the serum phosphorus clearance using the analysis of Spearman's single linear correlation, including predialysis serum phosphate level, CRR, membrane surface area of the dialyzer, effective blood flow rate, the blood chamber volume, and hematocrit. In an overall multivariate analysis, pre-P, CRR, membrane SA, and Qb were identified as independent risk factors associated with the serum phosphorus clearance. In conclusion, HD could effectively clear serum phosphorus. The analysis of CRR might help to estimate serum phosphorus reduction ratio.
Departments of Nephrology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Qiyao
Q
Yu
Departments of Nephrology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Yaling
Y
Bai
Departments of Nephrology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Junxia
J
Zhang
Departments of Nephrology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Liwen
L
Cui
Departments of Nephrology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Huiran
H
Zhang
Departments of Nephrology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Jinsheng
J
Xu
Departments of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Chao
C
Gao
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D005402:Fistula / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D015999:Multivariate Analysis; D010710:Phosphates / Q000737:chemistry*; D010758:Phosphorus / Q000097:blood*; D006435:Renal Dialysis; D051436:Renal Insufficiency, Chronic / Q000150:complications / Q000628:therapy; D012307:Risk Factors; D016896:Treatment Outcome
D010710:Phosphates; D010758:Phosphorus