Plasmonic nanobiosensor with chain reaction amplification mechanism.
Herein we demonstrate a plasmonic nanobiosensor that explores chain reaction amplification mechanisms to transduce chemical signals released in biocatalytic reactions, turning optical signals into a visual spectral range. The sensor has a very simple design: gold nanoparticles resting in the surface of a grafted P2VP film. Changes in the gold nanoparticles' position causes changes in the plasmon coupling mode. This is detected by means of a maximum absorbance shift.
Institute of Biosciences, Department of Chemistry and Biochemistry, UNESP, Botucatu, SP (Brazil), Fax: (+55) 14-38800576.
Lucas C
LC
Recco
Ihor
I
Tokarev
Sergiy
S
Minko
Valber A
VA
Pedrosa
D055162:Biocatalysis; D015374:Biosensing Techniques; D002712:Chlorides / Q000737:chemistry; D005290:Ferric Compounds / Q000737:chemistry; D005947:Glucose / Q000032:analysis; D005949:Glucose Oxidase / Q000378:metabolism; D006046:Gold / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry; D008689:Methacrylates / Q000737:chemistry; D036103:Nanotechnology; D011108:Polymers / Q000737:chemistry; D020349:Surface Plasmon Resonance
D002712:Chlorides; D005290:Ferric Compounds; D008689:Methacrylates; D011108:Polymers; C008384:methacrylic acid; D006046:Gold; D005949:Glucose Oxidase; D005947:Glucose; C024555:ferric chloride
biopolymerization; biosensors; nanotechnology; plasmonic platforms; polymerization