Bone loss at implant with titanium abutments coated by soda lime glass containing silver nanoparticles: a histological study in the dog.
The aim of the present study was to evaluate bone loss at implants connected to abutments coated with a soda-lime glass containing silver nanoparticles, subjected to experimental peri-implantitis. Also the aging and erosion of the coating in mouth was studied. Five beagle dogs were used in the experiments. Three implants were placed in each mandible quadrant: in 2 of them, Glass/n-Ag coated abutments were connected to implant platform, 1 was covered with a Ti-mechanized abutment. Experimental peri-implantitis was induced in all implants after the submarginal placement of cotton ligatures, and three months after animals were euthanatized. Thickness and morphology of coating was studied in abutment cross-sections by SEM. Histology and histo-morphometric studies were carried on in undecalfied ground slides. After the induced peri-implantitis: 1.The abutment coating shown losing of thickness and cracking. 2. The histometry showed a significant less bone loss in the implants with glass/n-Ag coated abutments. A more symmetric cone of bone resorption was observed in the coated group. There were no significant differences in the peri-implantitis histological characteristics between both groups of implants. Within the limits of this in-vivo study, it could be affirmed that abutments coated with biocide soda-lime-glass-silver nanoparticles can reduce bone loss in experimental peri-implantitis. This achievement makes this coating a suggestive material to control peri-implantitis development and progression.
Facultad Medicina y Odontología, Universidad de Santiago de Compostela (USC), Galicia, Spain.
Arturo
A
Martinez
Instituto de Cerámica de Galicia, Universidad de Santiago de Compostela (USC), Galicia, Spain.
Francisco
F
Guitián
Nanomaterials and Nanotechnology Research Center (CINN-CSIC) - Universidad de Oviedo (UO) - Principado de Asturias, Llanera, Spain.
Roberto
R
López-Píriz
Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC), Madrid, Spain.
José F
JF
Bartolomé
Nanomaterials and Nanotechnology Research Center (CINN-CSIC) - Universidad de Oviedo (UO) - Principado de Asturias, Llanera, Spain.
Belén
B
Cabal
Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC), Madrid, Spain.
Leticia
L
Esteban-Tejeda
Nanomaterials and Nanotechnology Research Center (CINN-CSIC) - Universidad de Oviedo (UO) - Principado de Asturias, Llanera, Spain.
Ramón
R
Torrecillas
Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC), Madrid, Spain.
José S
JS
Moya
D016301:Alveolar Bone Loss / Q000209:etiology / Q000473:pathology*; D000818:Animals; D017610:Calcium Compounds; D000044:Dental Abutments; D015921:Dental Implants / Q000009:adverse effects*; D004285:Dogs; D005898:Glass; D053768:Metal Nanoparticles / Q000009:adverse effects* / Q000737:chemistry; D010087:Oxides; D057873:Peri-Implantitis / Q000503:physiopathology; D012834:Silver; D014025:Titanium
D017610:Calcium Compounds; D015921:Dental Implants; D010087:Oxides; D012834:Silver; C016538:lime; D014025:Titanium