[The application of recombinant Bacillus Calmette-Guérin vaccine and its vector in infectious disease].
Recent studies show that the vector of recombinant Bacillus Calmette-Guérin (rBCG) has a series of advantages. With exogenous gene and vaccine in one inoculation, it can obtain strong and persistent immune response at one time so that BCG is considered as a kind of ideal vector for live recombinant vaccine. This review outlines the application of rBCG vaccine and its vector in infectious diseases caused by bacteria, viruses, other microorganisms and parasites.
The College of Pre-clinic, Xinjiang Medical University, Urumqi 830011, China.
Tursun
T
Zulpiya
The College of Pre-clinic, Xinjiang Medical University, Urumqi 830011, China.
Jianbing
J
Ding
D016915:AIDS Vaccines / Q000235:genetics / Q000276:immunology; D000942:Antigens, Bacterial / Q000235:genetics / Q000276:immunology; D001500:BCG Vaccine / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D003140:Communicable Disease Control / Q000379:methods*; D005822:Genetic Vectors / Q000235:genetics*; D015658:HIV Infections / Q000517:prevention & control; D015497:HIV-1; D009169:Mycobacterium tuberculosis; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000235:genetics / Q000276:immunology*; D014376:Tuberculosis / Q000517:prevention & control; D014614:Vaccines, Synthetic / Q000276:immunology
D016915:AIDS Vaccines; D000942:Antigens, Bacterial; D001500:BCG Vaccine; D011994:Recombinant Proteins; D014614:Vaccines, Synthetic