Direct C-F bond formation using photoredox catalysis.
We have developed the first example of a photoredox catalytic method for the formation of carbon-fluorine (C-F) bonds. The mechanism has been studied using transient absorption spectroscopy and involves a key single-electron transfer from the (3)MLCT (triplet metal-to-ligand charge transfer) state of Ru(bpy)3(2+) to Selectfluor. Not only does this represent a new reaction for photoredox catalysis, but the mild reaction conditions and use of visible light also make it a practical improvement over previously developed UV-mediated decarboxylative fluorinations.
Department of Chemistry, University of British Columbia , 2036 Main Mall, Vancouver, British Columbia, V6T 1Z1, Canada.
Montserrat
M
Rueda-Becerril
Olivier
O
Mahé
Myriam
M
Drouin
Marek B
MB
Majewski
Julian G
JG
West
Michael O
MO
Wolf
Glenn M
GM
Sammis
Jean-François
JF
Paquin