Antistaphylococcal action of lacto- and bifidobacteria and interleukn-2.
Antistaphylococcal action of Lactobacillus delbrueckii subsp. bulgaricus IMV B-7281, L. acidophilus LMV B-7279 and Bifidobacterium animalis VKB as well as interleukin-2 (IL-2) has been determined on the model of experimental staphylococcal infection in mice. It has been established that peroral administration of certain probiotic strains of lacto- and bifidobacteria or composition L. acidophilus LMV B-7279--L. delbrueckii subsp. bulgaricus IMV B-7281 with IL-2 to mice favored the reducing of terms of staphylococcus persistence in the kidneys of experimental mice. The studied schemes are promising for treatment of patients with surgical infection.
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Acad Zabolotny St., Kyiv, D03680, Ukraine.
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Mokrozub
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Acad Zabolotny St., Kyiv, D03680, Ukraine.
L M
LM
Lazarenko
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Acad Zabolotny St., Kyiv, D03680, Ukraine.
L P
LP
Babenko
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Acad Zabolotny St., Kyiv, D03680, Ukraine.
L M
LM
Shinkarenko
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Acad Zabolotny St., Kyiv, D03680, Ukraine.
O M
OM
Demchenko
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Acad Zabolotny St., Kyiv, D03680, Ukraine.
M Ya
MY
Spivak
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Acad Zabolotny St., Kyiv, D03680, Ukraine.
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Bila
D000818:Animals; D001644:Bifidobacterium / Q000502:physiology*; D015169:Colony Count, Microbial; D003131:Combined Modality Therapy; D007274:Injections, Intraperitoneal; D007376:Interleukin-2 / Q000494:pharmacology*; D007668:Kidney / Q000187:drug effects / Q000382:microbiology; D007778:Lactobacillus / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D019936:Probiotics / Q000494:pharmacology*; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development
D007376:Interleukin-2