Impaired taste and increased mortality in acutely hospitalized older people.
Taste ability is known to be impaired in elderly and even more so in acutely hospitalized elderly people. To our knowledge, no study has investigated the association between taste impairment and mortality. Our aim was to examine this association in acutely hospitalized older people. In a prospective study, 200 acutely hospitalized elderly people ≥70 years of age were included between November 2009 and October 2010 at the Oslo University Hospital, Norway. Exclusion criteria were cognitive impairment, nursing home residency, and terminal diseases. Comorbidity was registered with the Cumulative Illness Rating Scale, in addition to recording of age, gender, smoking, education, and number of medications. Taste ability was assessed quantitatively with the "taste strips method" in 174 patients (mean age: 84 years). Mortality until 1 January 2012 was obtained from hospital records. Fifty-six patients died during the observation period. The relative risk of death in total taste score quartile 4 compared with total taste score quartile 1 was 0.31 (95% confidence interval [95% CI]: 0.14-0.69, P = 0.004), after adjusting for age, gender, smoking, education, and Cumulative Illness Rating Scale. Adjusted 1-year mortality decreased from 30% in total taste score quartile 1 to 9% in total taste score quartile 4. Thus, impaired taste appears to be strongly associated with mortality in acutely hospitalized elderly people.
The Faculty of Dentistry, University of Oslo, PO Box 1109, Blindern, 0317 Oslo, Norway. kirsso@odont.uio.no.
Kirsten
K
Solemdal
Christina
C
Møinichen-Berstad
Morten
M
Mowe
Thomas
T
Hummel
Leiv
L
Sandvik
D000368:Aged; D000369:Aged, 80 and over; D003710:Demography; D005260:Female; D006760:Hospitalization; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D012907:Smoking; D013651:Taste Disorders / Q000175:diagnosis / Q000401:mortality*; D013652:Taste Threshold / Q000502:physiology*
elderly; survival; taste ability; taste strips