Comparison between prescription of regular or on-demand ibuprofen on postoperative pain after single-visit root canal treatment of teeth with irreversible pulpitis.
BACKGROUND
Pain management is very important in endodontic practice. The aim of this study was to compare the effect on pain relief of on-demand versus regular prescription of ibuprofen after single-visit root canal treatment in teeth with irreversible pulpitis.


METHODS
Sixty mandibular and maxillary molar teeth with irreversible pulpitis without spontaneous pain had single-visit root canal treatment. After this treatment, patients were randomly allocated to 2 groups of 30 patients each. Patients in group 1 received a single dose of 400 mg ibuprofen and a rescue bag of the same medication to use if they felt pain and needed further medication. Patients in group 2 received the same medication as group 1 patients after treatment, and they were also provided with a prescription to use 400 mg ibuprofen every 6 hours for at least 24 hours. The patients were asked to rate their pain on a visual analog scale for up to 48 hours after treatment. The data were analyzed with Mann-Whiney, chi-square, Fisher exact, and McNemar tests.


RESULTS
Two patients were excluded because they did not return their pain record forms. Data analysis of the remaining 58 patients showed no significant difference in pain felt by the patients in groups 1 and 2 at either 24 or 48 hours after treatment (P = .849 and P = .732, respectively). Patients in group 2 used significantly more medication compared with patients in group 1 (P = .04).


CONCLUSIONS
In patients who had irreversible pulpitis with no moderate to severe spontaneous pain, prescribing ibuprofen on a regular basis after root canal treatment had no significant effect on pain relief compared with an on-demand regimen up to 48 hours after treatment.
Oral and Dental Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran. Electronic address: M_Parirokh@kmu.ac.ir.
Masoud
M
Parirokh
Endodontic Department, Kerman University of Medical Sciences, Kerman, Iran; Endodontic Department, Hormozgan Medical Sciences University, Bandar Abbas, Hormozgan, Iran.
Saeedeh
S
Sadr
Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Nouzar
N
Nakhaee
School of Dentistry, University of Western Australia, Perth, Australia.
Paul V
PV
Abbott
Oral and Dental Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Hamed
H
Manochehrifar
D000328:Adult; D016058:Analgesia, Patient-Controlled / Q000379:methods; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001729:Bismuth / Q000627:therapeutic use; D004853:Epoxy Resins / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006171:Gutta-Percha / Q000627:therapeutic use; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use*; D008297:Male; D008963:Molar / Q000473:pathology; D010147:Pain Measurement / Q000379:methods; D010149:Postoperative Pain / Q000188:drug therapy*; D055553:Prescription Drugs; D011446:Prospective Studies; D011671:Pulpitis / Q000628:therapy*; D012387:Root Canal Filling Materials / Q000627:therapeutic use; D018915:Root Canal Preparation / Q000295:instrumentation / Q000379:methods; D012390:Root Canal Therapy / Q000379:methods*; D012834:Silver / Q000627:therapeutic use; D014025:Titanium / Q000627:therapeutic use; D055815:Young Adult
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004853:Epoxy Resins; D055553:Prescription Drugs; D012387:Root Canal Filling Materials; D012834:Silver; C028044:epoxy resin AH-26; D006171:Gutta-Percha; D014025:Titanium; D001729:Bismuth; D007052:Ibuprofen
1 visit; Analgesic; ibuprofen; irreversible; molar; on demand; pain; postoperative; pulpitis; regular; single visit; teeth