Analysis of new biomarkers for cholangiocarcinoma.
Cholangiocarcinoma is one of the most serious diseases in northeast Thailand, where its incidence is reported to be the highest in the world. We tried to develop a new method to detect cholangiocarcinoma in the early stages using serum proteins. We found that after fluorescent labeling of the sugar moiety of serum proteins, a new peak was identified, which might be a promising marker for cholangiocarcinoma.
Nagahama Institute of Bio-Science and Technology, 1266 Tamura-cho, Nagahama, Shiga, 526-0829, Japan. m_miwa@nagahama-i-bio.ac.jp.
Masanao
M
Miwa
Gyokukou
G
You
Hideaki
H
Tanaka
Seigo
S
Taniguchi
Takahiro
T
Fujii
Kazuo
K
Kamemura
Masafumi
M
Suzaki
Takahiro
T
Isono
Ikuo
I
Tooyama
Masakazu
M
Tanaka
Petcharin
P
Srivatanakul
Chutiwan
C
Viwatthanasittiphong
Suleeporn
S
Sangrajrang
Thiravud
T
Khuhaprema
D001650:Bile Duct Neoplasms / Q000097:blood* / Q000175:diagnosis; D001653:Bile Ducts, Intrahepatic; D014408:Biomarkers, Tumor / Q000097:blood*; D001798:Blood Proteins / Q000032:analysis / Q000378:metabolism*; D016022:Case-Control Studies; D018281:Cholangiocarcinoma / Q000097:blood* / Q000175:diagnosis; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D012680:Sensitivity and Specificity; D013785:Thailand
D014408:Biomarkers, Tumor; D001798:Blood Proteins
Biliary tract cancer · Cholangiocarcinoma · Opisthorchis viverrini · Tumor marker