Two new phenolic compounds from the heartwood of Caesalpinia sappan L.
Two new phenolic compounds, epicaesalpin J and 7,10,11-trihydroxydracaenone, were isolated from the heartwood of Caesalpinia sappan L. Their structures were identified by spectroscopic analysis methods, such as 1D and 2D NMR, along with the high resolution mass spectral data. The NO inhibition activities of two new compounds and six known compounds were tested.
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Ming-Bo
MB
Zhao
Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Jun
J
Li
Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
She-Po
SP
Shi
College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China.
Chen-Qiu
CQ
Cai
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China. pengfeitu@vip.163.com.
Peng-Fei
PF
Tu
College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China.
Li
L
Tang
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Ke-Wu
KW
Zeng
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Yong
Y
Jiang
D000818:Animals; D029911:Caesalpinia / Q000737:chemistry* / Q000378:metabolism; D020128:Inhibitory Concentration 50; D053858:Metabolic Networks and Pathways; D017628:Microglia / Q000187:drug effects; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010636:Phenols / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D014934:Wood / Q000737:chemistry*
D010636:Phenols