Reproducibility of cardiac biomarkers response to prolonged treadmill exercise.
We examined the reproducibility of alterations in cardiac biomarkers after two identical bouts of prolonged exercise in young athletes. Serum high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels were assessed before and after exercise. Significant rises in median hs-cTnT and NT-proBNP occurred in both trials. While the absolute changes in hs-cTnT were smaller after trial 2, the pattern of change was similar and the delta scores were significantly related. However, the change in NT-proBNP was not correlated between trials. The hs-cTnT release demonstrates some consistency after exercise although the blunted hc-cTnT response requires further study.
China Institute of Sport Science , Beijing , China .
Ye
Y
Tian
Jinlei
J
Nie
Keith P
KP
George
Chuanye
C
Huang
D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D006400:Hematocrit; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D010807:Physical Endurance; D015203:Reproducibility of Results; D012420:Running / Q000502:physiology; D020107:Troponin T / Q000097:blood*; D016277:Ventricular Function, Left; D055815:Young Adult
D015415:Biomarkers; D006454:Hemoglobins; D010446:Peptide Fragments; D020107:Troponin T; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain