Validation of respiratory inductive plethysmography (LifeShirt) in obesity hypoventilation syndrome.
Validation of respiratory inductive plethysmography (LifeShirt system) (RIPLS) for tidal volume (VT), minute ventilation (V˙E), and respiratory frequency (fB) was performed among people with untreated obesity hypoventilation syndrome (OHS) and controls. Measures were obtained simultaneously from RIPLS and a spirometer during two tests, and compared using Bland Altman analysis. Among 13 OHS participants (162 paired measures), RIPLS-spirometer agreement was unacceptable for VT: mean difference (MD) 3 mL (1%); limits of agreement (LOA) -216 to 220 mL (±36%); V˙E MD 0.1 L min(-1) (2%); LOA -4.1 to 4.3 L min(-1) (±36%); and fB: MD 0.2 br min(-1) (2%); LOA -4.6 to 5.0 br min(-1) (±27%). Among 13 controls (197 paired measures), RIPLS-spirometer agreement was acceptable for fB: MD -0.1 br min(-1) (-1%); LOA -1.2 to 1.1 br min(-1) (±12%), but unacceptable for VT: MD 5 mL (1%); LOA -160 to 169 mL (±20%) and V˙E: MD 0.1 L min(-1) (1%); LOA -1.4 to 1.5 L min(-1) (±20%). RIPLS produces valid measures of fB among controls but not OHS patients, and is not valid for quantifying respiratory volumes among either group.
Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Level 11, Building 75, Missenden Road, Camperdown, NSW 2050, Australia; Clinical and Rehabilitation Sciences Research Group, Faculty of Health Sciences, The University of Sydney, Cumberland Campus C42, 75 East Street, Lidcombe, NSW 2141, Australia. Electronic address: carly.hollier@sswahs.nsw.gov.au.
Carly A
CA
Hollier
Clinical and Rehabilitation Sciences Research Group, Faculty of Health Sciences, The University of Sydney, Cumberland Campus C42, 75 East Street, Lidcombe, NSW 2141, Australia. Electronic address: alison.harmer@sydney.edu.au.
Alison R
AR
Harmer
Faculty of Health Sciences, Australian Catholic University, Level 2, 173 Pacific Highway, North Sydney, NSW 2060, Australia. Electronic address: lyndal.maxwell@acu.edu.au.
Lyndal J
LJ
Maxwell
Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Level 11, Building 75, Missenden Road, Camperdown, NSW 2050, Australia. Electronic address: collette.menadue@sswahs.nsw.gov.au.
Collette
C
Menadue
Faculty of Health, University of Canberra, Building 12, Level D, ACT 2601, Australia. Electronic address: grant.willson@canberra.edu.au.
Grant N
GN
Willson
Ageing, Work and Health Research Group, Faculty of Health Sciences, The University of Sydney, Cumberland Campus C42, 75 East Street, Lidcombe, NSW 2141, Australia. Electronic address: deborah.black@sydney.edu.au.
Deborah A
DA
Black
Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Level 11, Building 75, Missenden Road, Camperdown, NSW 2050, Australia. Electronic address: amanda.piper@sswahs.nsw.gov.au.
Amanda J
AJ
Piper
D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010845:Obesity Hypoventilation Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D010991:Plethysmography / Q000295:instrumentation*; D012119:Respiration; D013147:Spirometry; D013990:Tidal Volume; D055105:Waist Circumference
Hypercapnia; LifeShirt; Obesity; Obesity hypoventilation syndrome; Respiratory inductive plethysmography; Ventilation