Topography-based keratoconus progression after corneal collagen crosslinking.
OBJECTIVE
The aim of this study was to report 2 cases with topographic keratoconus progression despite stability for a long-term period after corneal collagen crosslinking (CXL).


METHODS
This is a case report.


RESULTS
Two patients with progressive keratoconus underwent CXL treatment. Four and 5 years postoperatively, a topographic examination revealed an increase in the keratometric values indicating keratoconus progression.


CONCLUSIONS
Post-CXL, topographic keratoconus progression may occur several years after, despite stability for a long-term period.
*Vardinoyiannion Eye Institute of Crete (VEIC), Faculty of Medicine, University of Crete, Heraklion, Greece; and †Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL.
George D
GD
Kymionis
Alexandra E
AE
Karavitaki
Michael A
MA
Grentzelos
Dimitrios A
DA
Liakopoulos
Konstantinos I
KI
Tsoulnaras
George A
GA
Kontadakis
D000328:Adult; D003094:Collagen / Q000378:metabolism*; D003319:Corneal Stroma / Q000378:metabolism*; D019781:Corneal Topography; D003432:Cross-Linking Reagents / Q000627:therapeutic use*; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D007640:Keratoconus / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D012256:Riboflavin / Q000627:therapeutic use; D014466:Ultraviolet Rays; D014792:Visual Acuity / Q000502:physiology
D003432:Cross-Linking Reagents; D017319:Photosensitizing Agents; D003094:Collagen; D012256:Riboflavin