Resonance activation and collision-induced-dissociation of ions using rectangular wave dipolar potentials in a digital ion trap mass spectrometer.
Collision-induced dissociation (CID) of ions by resonance activation in a quadrupole ion trap is usually accomplished by resonance exciting the ions to higher kinetic energy, whereby the high kinetic energy ions collide with a bath gas, such as helium or argon, inside the trap and dissociate to fragments. A new ion activation method using a well-defined rectangular wave dipolar potential formed by dividing down the trapping rectangular waveform is developed and examined herein. The mass-selected parent ions are resonance excited to high kinetic energies by simply changing the frequency of the rectangular wave dipolar potential and dissociation proceeds. A relationship between the ion mass and the activation waveform frequency is also identified and described. This highly efficient (CID) procedure can be realized by simply changing the waveform frequency of the dipolar potential, which could certainly simplify tandem mass spectrometry analysis methods.
Department of Chemistry and Laser Chemistry Institute, Fudan University, Shanghai, China.
Fuxing
F
Xu
Liang
L
Wang
Xinhua
X
Dai
Xiang
X
Fang
Chuan-Fan
CF
Ding
D005740:Gases / Q000737:chemistry; D007477:Ions / Q000032:analysis* / Q000737:chemistry*; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods*; D009842:Oligopeptides / Q000737:chemistry; D012110:Reserpine / Q000737:chemistry
D005740:Gases; D007477:Ions; D009842:Oligopeptides; D012110:Reserpine