The cognitive mechanisms underlying perspective taking between conversational partners: evidence from speakers with Alzheimer׳s disease.
Successful communication requires speakers to consider their listeners׳ perspectives. Little is known about how this ability changes in Alzheimer׳s Disease (AD) although such knowledge could reveal the cognitive mechanisms fundamental to perspective-taking ability, and reveal which cognitive deficits are fundamental to communication disorders in AD. Patients with mild to moderate AD and age and education matched controls were tested in a communicative perspective-taking task, and on measures of executive control, general cognitive functioning, and lexical retrieval. Patients׳ ability to perform the perspective-taking task was significantly correlated with performance on measures of general cognitive functioning, visual scanning and construction, response conflict and attention. Measures of lexical retrieval tended not to be correlated with performance on the communication task with one exception: semantic but not letter fluency predicted a derived score of perspective-taking ability. These findings broaden our understanding of the cognitive mechanisms underlying perspective taking, and suggest that impairments in perspective taking in AD occur during utterance planning, and at a relatively early processing stage which involves rapid visual scanning and problem solving, rather than during retrieval of lexical items needed to speak. More broadly, these data reveal executive function and semantic deficits, but not problems with lexical retrieval, as more fundamental to the basis of cognitive changes associated with AD.
University of California, San Diego, Department of Psychology, 9500 Gilman Drive, La Jolla, CA 92093-0109, USA. Electronic address: lwardlow@ucsd.edu.
Liane
L
Wardlow
University of California, San Diego, Department of Psychiatry, 9500 Gilman Drive, La Jolla, CA 92093-0948, USA. Electronic address: iva.m.ivanova@gmail.com.
Iva
I
Ivanova
University of California, San Diego, Department of Psychiatry, 9500 Gilman Drive, La Jolla, CA 92093-0948, USA. Electronic address: tgollan@ucsd.edu.
Tamar H
TH
Gollan
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000150:complications*; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D003142:Communication; D003147:Communication Disorders / Q000175:diagnosis / Q000209:etiology*; D056344:Executive Function / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall; D009483:Neuropsychological Tests; D012660:Semantics; D013064:Speech Disorders / Q000209:etiology*
Alzheimer׳s disease; Communication; Executive function; Language production