Organelle size: a cilium length signal regulates IFT cargo loading.
Cilia grow by assembling structural precursors delivered to their tips by intraflagellar transport. New work on ciliary length control indicates that, during ciliary growth, cilia send a length signal to the cytoplasm that regulates cargo loading onto the constitutively trafficking intraflagellar transport machinery.
MOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Junmin
J
Pan
Department of Cell Biology, University of Texas Southwestern Medical School, Dallas, TX 75390, USA. Electronic address: William.Snell@UTSouthwestern.edu.
William J
WJ
Snell
D016825:Chlamydomonas reinhardtii / Q000378:metabolism*; D002923:Cilia / Q000378:metabolism*; D008954:Models, Biological; D010940:Plant Proteins / Q000378:metabolism*
D010940:Plant Proteins