Effect of food intake on left ventricular wall stress.
OBJECTIVE
Left ventricular wall stress has been investigated in a variety of populations, but the effect of food intake has not been evaluated. We assessed whether left ventricular wall stress is affected by food intake in healthy subjects.


METHODS
Twenty-three healthy subjects aged 25.6 ± 4.5 years were investigated. Meridional end-systolic wall stress (ESS) and circumferential end-systolic wall stress (cESS) were measured before, 30 minutes after, and 110 minutes after a standardised meal.


RESULTS
Both ESS and cESS decreased significantly (P < 0.001) from fasting values 30 minutes after the meal, and had not returned to baseline after 110 minutes. ESS decreased from 65 ± 16 kdynes/cm2 (fasting) to 44 ± 12 kdynes/cm2 30 minutes after, and to 58 ± 13 kdynes/cm2 110 minutes after eating. cESS decreased from 98 ± 24 kdynes/cm2 to 67 ± 18 kdynes/cm2 30 minutes after, and to 87 ± 19 kdynes/cm2 110 minutes after the meal.


CONCLUSIONS
This study shows that left ventricular wall stress is affected by food intake in healthy subjects.
Department of Clinical Sciences, Unit of Clinical Physiology and Nuclear Medicine, Skåne University Hospital, Lund University, Malmö, Sweden. ylva.gardinger@skane.se.
Ylva
Y
Gårdinger
Joanna
J
Hlebowicz
Ola
O
Björgell
Magnus
M
Dencker
D000328:Adult; D004435:Eating / Q000502:physiology*; D004453:Echoencephalography / Q000379:methods; D055119:Elastic Modulus / Q000502:physiology; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013314:Stress, Mechanical; D013318:Stroke Volume / Q000502:physiology*; D014655:Vascular Resistance; D016277:Ventricular Function, Left / Q000502:physiology*