[Hemophagocytic syndrome associated with Epstein-Barr virus. Presentation of a case and treatment in the Resuscitation Unit].
We report the case of a 17 year old male patient, who was admitted to the Resuscitation Unit with the diagnosis of hemophagocytic syndrome, associated with infection by Epstein-Barr virus with unfavorable outcome. Hemophagocytic syndrome is a pathological immune activation syndrome due to the production/uncontrolled modulation of some cytokines. Its clinical signs and symptoms, defined by consensus criteria HLH-2004, are not pathognomonic, and often appear sequentially, thus suspicion should be followed by aggressive supportive therapy combined with early specific treatment of the triggering factor, as it is the only way to improve survival in patients with multiple organic failure as a result.
Servicio de Anestesiología y Reanimación, Complexo Hospitalario de Ourense, Ourense, España. Electronic address: olalla.figueiredo.gonzalez@sergas.es.
O
O
Figueiredo González
Servicio de Hematología y Hemoterapia, Complexo Hospitalario de Ourense, Ourense, España.
M
M
Iglesias Fernández
Servicio de Anestesiología y Reanimación, Complexo Hospitalario de Ourense, Ourense, España.
A
A
Río Gómez
Servicio de Hematología y Hemoterapia, Complexo Hospitalario de Ourense, Ourense, España.
C
C
Ulibarrena Redondo
Servicio de Anestesiología y Reanimación, Complexo Hospitalario de Ourense, Ourense, España.
M L
ML
Casas García
D000293:Adolescent; D000761:Anesthesia Department, Hospital; D020031:Epstein-Barr Virus Infections / Q000150:complications* / Q000628:therapy*; D017809:Fatal Outcome; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000628:therapy* / Q000821:virology*; D008297:Male
Carga viral; Encefalitis; Encephalitis; Epstein-Barr virus; Hemophagocytic lymphohistiocytosis; Hemophagocytic syndrome; Linfohistiocitosis hemofagocítica; Síndrome hemofagocítico; Thrombocytopenia; Trombocitopenia; Viral load; Virus de Epstein-Barr