Acute onset of a vesiculopustular rash in an ICU patient.
A 63 year-old woman with hyperthyroidism was admitted to the Medical Intensive Care Unit for ARDS following damage to her lungs from propylthiouracil. She was placed on 250 mg SSKI PO TID as an alternative therapy until thyroidectomy could be performed. Four days after admission, she abruptly developed an acneiform rash on her face, shown to be iododerma. The eruption rapidly resolved after discontinuation of the SSKI.
Icahn School of Medicine.
Amylynne J
AJ
Frankel
Moneeb
M
Ahmad
Marcel
M
Perl
Jonathan
J
Yao
Fred
F
Pereira
D013956:Antithyroid Agents / Q000009:adverse effects / Q000627:therapeutic use; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D004630:Emergencies; D005148:Facial Dermatoses / Q000139:chemically induced / Q000175:diagnosis; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008875:Middle Aged; D020556:Neutrophil Infiltration; D011193:Potassium Iodide / Q000009:adverse effects* / Q000627:therapeutic use; D011441:Propylthiouracil / Q000009:adverse effects / Q000627:therapeutic use; D012128:Respiratory Distress Syndrome / Q000139:chemically induced / Q000628:therapy*; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D013971:Thyrotoxicosis / Q000188:drug therapy
D013956:Antithyroid Agents; D011193:Potassium Iodide; D011441:Propylthiouracil