A clinical review of maternal bacteremia.
OBJECTIVE
To carry out a 4-year review of cases of bacteremia among obstetric patients.


METHODS
In a retrospective review, all cases of maternal bacteremia between 2009 and 2012 were identified from the laboratory database of Coombe Women and Infants University Hospital, Dublin, Ireland. The clinical records of each case were assessed.


RESULTS
During the study period, 37,584 obstetric patients attended the hospital. There were 58 cases of bacteremia: 19 were diagnosed prepartum, 20 intrapartum, and 19 postpartum. There were no maternal deaths. Two cases resulted in septic shock. Four cases were associated with early pregnancy loss, and 2 with stillbirth. Fifty-four cases occurred among 34,956 women who delivered a neonate weighing 500 g or more (0.15%). Escherichia coli most frequently caused prepartum and postpartum bacteremia, whereas Streptococcus agalactiae (β-hemolytic, Lancefield group B) most frequently caused intrapartum bacteremia. There was no association between the development of bacteremia and maternal risk factors including employment status, obesity, parity, smoking status, and maternal age. Most organisms cultured were sensitive to first-line antibiotics; there were no cases of bacteremia caused by multi-drug resistant organisms.


CONCLUSIONS
The incidence of maternal bacteremia in the study population was low and was usually associated with good maternal and fetal outcomes.
UCD Centre for Human Reproduction, Coombe Women and Infants University Hospital, Dublin, Ireland. Electronic address: amyohiggins@rcsi.ie.
Amy C
AC
O'Higgins
UCD Centre for Human Reproduction, Coombe Women and Infants University Hospital, Dublin, Ireland.
Aileen F
AF
Egan
UCD Centre for Human Reproduction, Coombe Women and Infants University Hospital, Dublin, Ireland.
Olivia C
OC
Murphy
UCD Centre for Human Reproduction, Coombe Women and Infants University Hospital, Dublin, Ireland.
Christopher
C
Fitzpatrick
UCD Centre for Human Reproduction, Coombe Women and Infants University Hospital, Dublin, Ireland.
Sharon R
SR
Sheehan
UCD Centre for Human Reproduction, Coombe Women and Infants University Hospital, Dublin, Ireland.
Michael J
MJ
Turner
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007494:Ireland; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012307:Risk Factors; D012772:Shock, Septic / Q000453:epidemiology; D055815:Young Adult
D000900:Anti-Bacterial Agents
Maternal bacteremia; Maternal morbidity; Pregnancy infection