[Epidemiology of type 1 diabetes mellitus in children in Spain].
BACKGROUND
Epidemiological studies in many regions and countries have contributed to determining the epidemiology of type 1 diabetes (T1DM) in children less than 15 years old. Studies in many regions of Spain have been published, but the national incidence is not really known.


METHODS
A review was made of the publications on the epidemiology of T1DM in Spain, selecting the references on patients less than 15 years old.


RESULTS
Many epidemiological studies on T1DM in almost all regions in Spain have been published. The methodology of these studies is heterogeneous, with variations in geographical definition, duration, period of study, limit of age, and data collection. The incidence rates are variable, from 11.5 cases per 100,000/year in Asturias to 27.6 in Castilla-La Mancha. Some studies report the percentage of diabetic ketoacidosis at the time of diagnosis, which is usually in the range of 25-40%.


CONCLUSIONS
Although there have been various epidemiological studies on T1DM in almost all regions in Spain, the methodology is heterogeneous. The mean incidence of T1DM in children less than 15 years old in Spain, stimated from the selected studies is 17,69 cases per 100,000/year. T1DM registers need to be created and updated, using standardized methodology, to get more reliable data of the epidemiology of T1DM in Spain in the near future.
Centro de Salud de Barbastro, Huesca, España. Electronic address: santycon@terra.com.
S
S
Conde Barreiro
Unidad de diabetes infantil, Hospital Universitario Miguel Servet, Zaragoza, España.
M
M
Rodríguez Rigual
Servicio de Pediatría, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España.
G
G
Bueno Lozano
Servicio de Endocrinología Pediátrica, Hospital Maternoinfantil Carlos Haya, Málaga, España.
J P
JP
López Siguero
Unidad de Cuidados Intensivos, Hospital de Barbastro, Huesca, España.
B
B
González Pelegrín
Dirección General de Salud Pública del Gobierno de Aragón, Zaragoza, España.
M P
MP
Rodrigo Val
Dirección General de Salud Pública del Gobierno de Aragón, Zaragoza, España.
M L
ML
Compés Dea
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007223:Infant; D013030:Spain / Q000453:epidemiology
Diabetes mellitus tipo 1; Epidemiology; Epidemiología; España; Incidence; Incidencia; Registers; Registros; Spain; Type 1 diabetes mellitus