A unified approach to the important protein kinase inhibitor balanol and a proposed analogue.
A common approach to the important protein kinase inhibitor (-)-balanol and an azepine-ring-modified balanol derivative has been developed using an efficient fragment coupling protocol which proceeded in good overall yield.
Department of Chemistry, University of Kalyani, Kalyani - 741235, West Bengal, India.
Tapan
T
Saha
Department of Chemistry, University of Kalyani, Kalyani - 741235, West Bengal, India.
Ratnava
R
Maitra
Department of Chemistry, University of Kalyani, Kalyani - 741235, West Bengal, India.
Shital K
SK
Chattopadhyay
Garner’s aldehyde; PKC inhibitor; azepane; balanol; ring-closing metathesis