[Association of a single nucleotide substitution in intergenic region of chromosome 4 with traits of egg quality in domestic chickens].
The association of SNP2-1 with egg quality traits in domestic chickens was analyzed. SNP2-1 alleles were significantly associated with the thickness of eggshells in chickens of the UK-72 line. The substitution of the SNP2-1 allele Tfor the C allele had an effect of 35 +/- 15 microm, which corresponds to one standard deviation. For this trait, the effect of the Tallele was dominant. SNP2-1 was also associated with other traits, including shell weight, egg-laying capacity in 60-week-old chickens (line UK-72), and egg weight in 60-week-old chickens (line cross CD). Thus, the QTL marked with SNP2-1 has a pleiotropic effect that depends on the chicken strain. Candidate genes located on chromosome 4 in close vicinity of SNP2-1 are discussed.
O Yu
OY
Barkova
M G
MG
Smaragdov
D000818:Animals; D017849:Animals, Inbred Strains; D002645:Chickens / Q000235:genetics*; D002875:Chromosomes / Q000235:genetics*; D021901:DNA, Intergenic / Q000235:genetics*; D004531:Eggs / Q000592:standards*; D005787:Gene Frequency; D056726:Genetic Association Studies; D020641:Polymorphism, Single Nucleotide; D011200:Poultry / Q000235:genetics*; D040641:Quantitative Trait Loci; D019655:Quantitative Trait, Heritable
D021901:DNA, Intergenic