Cortical anaplastic ependymoma with significant desmoplasia: a case report and literature review.
Ectopic brain anaplastic ependymomas with no connection to the ventricles are rare. We present a rare case of a 25-year-old male who presented with generalized convulsions. Computed tomography (CT), Magnetic Resonance Imaging (MRI), and magnetic resonance spectroscopy (MRS) showed characters of an intra- and extra-axial lesion. Intraoperatively, the lesion was a cortical solid mass that had no connections to the dura or to the ventricle. The histological diagnosis showed an anaplastic ependymoma with WHO grade III with distinctive desmoplasia. A literature review of ectopic anaplastic ependymomas regarding their clinical presentations, management, and prognostic factors was performed. There is a need to establish a clinically based histopathological grading system for anaplastic ependymomas. Ectopic anaplastic ependymomas should be included in the preoperative differential diagnosis.
Neurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, Germany ; Neurosurgical Department, University of Kiel, 24105 Kiel, Germany.
Alaa Eldin
AE
Elsharkawy
Neurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, Germany.
Raid
R
Abuamona
Department of Clinical Neuropathology, Bremen, Germany.
Markus
M
Bergmann
Neurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, Germany.
Shadi
S
Salem
Pathological Department, Ludmillenstift Hospital, Meppen, Germany.
Evariste
E
Gafumbegete
Neurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, Germany.
Ernst
E
Röttger