Effect of paracetamol, dexketoprofen trometamol, lidocaine spray, and paracervical block application for pain relief during suction termination of first-trimester pregnancy.
The aim of the study was to investigate the analgesic efficacy of preoperative oral dexketoprofen trometamol, intravenous paracetamol, lidocaine spray, and paracervical block with ultracaine on curettage procedure. A total of 111 subjects with the request of pregnancy termination between 5 and 7 weeks of gestation were included in the study. The first group (control group) consisted of 20 participants without medication. The second group consisted of 25 participants receiving 2 puffs of lidocaine sprays on cervical mucosa. The third group consisted of 20 participants receiving oral 25 mg dexketoprofen trometamol. The fourth group consisted of 23 participants receiving 1000 mg intravenous paracetamol and the fifth group consisted of 23 participants receiving paracervical block with ultracaine. Paracervical block reduced pain score significantly in both intraoperative and postoperative periods. All analgesic procedures were significantly effective for reducing pain in postoperative period. Paracervical block may be the best method for reducing pain scores in intraoperative and postoperative periods during curettage procedure. All analgesic procedures such as lidocaine, paracetamol, ultracaine, and paracervical block with ultracaine can be used for reducing pain score in postoperative period. This trial is registered with NCT01947205.
Department of Obstetrics and Gynecology, Kayseri Education and Research Hospital of Medicine, 38210 Kayseri, Turkey.
Gökhan
G
Açmaz
Department of Obstetrics and Gynecology, Kayseri Military Hospital, Kayseri, Turkey.
Hüseyin
H
Aksoy
Clinic of Family Planning, Kayseri Education and Research Hospital of Medicine, 38210 Kayseri, Turkey.
Nil
N
Özoğlu
Department of Obstetrics and Gynecology, Kayseri Education and Research Hospital of Medicine, Kayseri, Turkey.
Ülkü
Ü
Aksoy
Department of Midwifery, Erciyes University School of Medicine, 38210 Kayseri, Turkey.
Evrim
E
Albayrak
D000028:Abortion, Induced / Q000379:methods*; D000082:Acetaminophen / Q000008:administration & dosage; D061605:Administration, Intravenous; D000284:Administration, Oral; D000328:Adult; D000773:Anesthesia, Obstetrical; D005260:Female; D006801:Humans; D007660:Ketoprofen / Q000008:administration & dosage / Q000031:analogs & derivatives; D008012:Lidocaine / Q000008:administration & dosage; D010146:Pain / Q000188:drug therapy*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D014325:Tromethamine / Q000008:administration & dosage
D014325:Tromethamine; D000082:Acetaminophen; D007660:Ketoprofen; D008012:Lidocaine; C118296:dexketoprofen trometamol