Galactose content of legumes, caseinates, and some hard cheeses: implications for diet treatment of classic galactosemia.
There are inconsistent reports on the lactose and/or galactose content of some foods traditionally restricted from the diet for classic galactosemia. Therefore, samples of cheeses, caseinates, and canned black, pinto, kidney, and garbanzo beans were analyzed for free galactose content using HPLC with refractive index or pulsed amperometric detection. Galactose concentrations in several hard and aged cheeses and three mild/medium Cheddars, produced by smaller local dairies, was <10 mg/100 g sample compared to 55.4 mg/100 g sample in four sharp Cheddars produced by a multinational producer. Galactose in sodium and calcium caseinate ranged from undetectable to 95.5 mg/100 g sample. Free galactose level in garbanzo beans was lower than previously reported at 24.6 mg/100 g sample; black beans contained 5.3 mg/100 g, and free galactose was not detected in red kidney or pinto beans. These data provide a basis for recommending inclusion of legumes, caseinate-containing foods, and some aged hard cheeses that had been previously restricted in the diet for individuals with galactosemia.
Division of Genetics and Metabolism, Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin-Madison , 1500 Highland Avenue, Madison, Wisconsin 53705, United States.
Sandra C
SC
Van Calcar
Laurie E
LE
Bernstein
Frances J
FJ
Rohr
Steven
S
Yannicelli
Gerard T
GT
Berry
Christine H
CH
Scaman
D002364:Caseins / Q000737:chemistry*; D002611:Cheese / Q000032:analysis*; D004032:Diet; D007887:Fabaceae / Q000737:chemistry*; D005690:Galactose / Q000032:analysis*; D005693:Galactosemias / Q000178:diet therapy*; D006801:Humans; D005694:UTP-Hexose-1-Phosphate Uridylyltransferase / Q000172:deficiency
D002364:Caseins; D005694:UTP-Hexose-1-Phosphate Uridylyltransferase; D005690:Galactose