The pivotal role of FDG-PET/CT in modern medicine.
The technology behind positron emission tomography (PET) and the most widely used tracer, 2-deoxy-2-[18F]fluoro-D-glucose (FDG), were both conceived in the 1970s, but the latest decade has witnessed a rapid emergence of FDG-PET as an effective imaging technique. This is not least due to the emergence of hybrid scanners combining PET with computed tomography (PET/CT). Molecular imaging has enormous potential for advancing biological research and patient care, and FDG-PET/CT is currently the most widely used technology in this domain. In this review, we discuss contemporary applications of FDG-PET and FDG-PET/CT as well as novel developments in quantification and potential future indications including the emerging new modality PET/magnetic resonance imaging.
Department of Nuclear Medicine, Odense University Hospital, Soender Boulevard 29, 5000 Odense, Denmark. Electronic address: soeren.hess@rsyd.dk.
Søren
S
Hess
Department of Nuclear Medicine, Odense University Hospital, Soender Boulevard 29, 5000 Odense, Denmark; Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Björn A
BA
Blomberg
Department of Radiology, University of Arkansas for Medical Science, Little Rock, AR.
Hongyun June
HJ
Zhu
Department of Nuclear Medicine, Odense University Hospital, Soender Boulevard 29, 5000 Odense, Denmark.
Poul Flemming
PF
Høilund-Carlsen
Division of Nuclear Medicine, University of Pennsylvania Perelman School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA.
Abass
A
Alavi
D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics*; D006801:Humans; D057054:Molecular Imaging / Q000379:methods*; D064847:Multimodal Imaging / Q000379:methods*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D014057:Tomography, X-Ray Computed / Q000379:methods*
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
2-deoxy-2-[18F]fluoro-D-glucose; FDG; PET/CT; Positron emission tomography/computed tomography; molecular imaging