Treatment of congenital generalized lymphangiectasia with propranolol in a preterm infant.
Generalized lymphangiectasia is a rare congenital disorder characterized by dilated lymphatic vessels with a fatal prognosis, especially in cases with thoracic involvement. We describe the use of propranolol in the therapy of generalized lymphangiectasia in a preterm infant with hydrops fetalis. Propranolol was well tolerated and effective within the first months. It remains to be shown whether propranolol is a treatment option for infants with generalized lymphangiectasia.
Departments of Neonatology.
Christine
C
Poralla
Sabine
S
Specht
Mark
M
Born
Annette
A
Müller
Peter
P
Bartmann
Andreas
A
Müller
D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000188:drug therapy*; D008200:Lymphangiectasis / Q000151:congenital* / Q000188:drug therapy*; D011433:Propranolol / Q000627:therapeutic use*
D011433:Propranolol
VEGF; generalized lymphangiectasia; preterm infant; propranolol