[Esophageal atresia: prevalence, prenatal diagnosis and prognosis].
Esophageal atresia (EA) is a rare congenital malformation (1 in 2,500 to 3,500 births). Prenatal diagnosis (PN) is particularly interesting allowing search for associated malformations related to worse prognosis forms (reference ultrasound, MRI and amniocentesis) and planning the birth in an adapted medico-surgical center. Diagnosis of EA is usually suspected because of indirect and non-specific signs: association of polyhydramnios and absent or small stomach bubble. The visualization in ultrasound or MRI of cervical or thoracic fluid image corresponding to the expansion of the bottom of upper esophageal ("pouch sign") increases the specificity of diagnosis. However, prenatal diagnosis remains difficult and less than 50 % of EA are diagnosed prenatally. Biochemical analysis could improve these results. If EA is confirmed at birth, surgical management consists in a primary end-to-end anastomosis in first days of life, or in two-steps surgery if the defect is too large. Although current prognosis of EA is good, frequency of surgical complications and esophageal lesions secondary to gastroesophageal reflux justify a systematic and multidisciplinary extended follow-up.
Pôle femme-mère-nouveau-né, clinique d'obstétrique, hôpital Jeanne-de-Flandre, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille, France. Electronic address: charles.garabedian@gmail.com.
C
C
Garabedian
Pôle femme-mère-nouveau-né, clinique d'obstétrique, hôpital Jeanne-de-Flandre, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille, France.
P
P
Vaast
Service d'imagerie de la femme, pôle de radiologie, hôpital Jeanne-de-Flandre, CHRU de Lille, 59037 Lille, France.
J
J
Bigot
Centre de référence des affections congénitales et malformatives de l'œsophage, hôpital Jeanne-de-Flandre, 59037 Lille, France.
R
R
Sfeir
Centre de référence des affections congénitales et malformatives de l'œsophage, hôpital Jeanne-de-Flandre, 59037 Lille, France; Université Lille Nord de France, 59037 Lille, France.
L
L
Michaud
Centre de référence des affections congénitales et malformatives de l'œsophage, hôpital Jeanne-de-Flandre, 59037 Lille, France; Université Lille Nord de France, 59037 Lille, France.
F
F
Gottrand
Service d'imagerie de la femme, pôle de radiologie, hôpital Jeanne-de-Flandre, CHRU de Lille, 59037 Lille, France.
P
P
Verpillat
Pôle femme-mère-nouveau-né, clinique d'obstétrique, hôpital Jeanne-de-Flandre, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille, France.
C
C
Coulon
Pôle femme-mère-nouveau-né, clinique d'obstétrique, hôpital Jeanne-de-Flandre, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille, France; Université Lille Nord de France, 59037 Lille, France.
D
D
Subtil
Pôle femme-mère-nouveau-né, clinique d'obstétrique, hôpital Jeanne-de-Flandre, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille, France; Université Lille Nord de France, 59037 Lille, France.
V
V
Houfflin Debarge
D004933:Esophageal Atresia / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D011379:Prognosis
Analyse biochimique amniotique; Atrésie de l’œsophage; Biochemical amniotic fluid; Diagnostic anténatal; Esophageal atresia; Fetal ultrasound; IRM; MRI; Prenatal diagnosis; Échographie fœtale