Conjunctival MALT lymphoma: utility of FDG PET/CT for diagnosis, staging, and evaluation of treatment response.
A 67-year-old woman was referred for staging of a mucosa-associated lymphoid tumor lymphoma involving the left conjunctiva. CT scan had shown paravertebral and pelvic masses, and a breast nodule. FDG PET/CT demonstrated moderately increased uptake in the left ocular conjunctiva and confirmed the paravertebral and pelvic masses and the breast nodule. Moreover, abnormal FDG uptake was shown in 2 breast nodules, the flank, the gluteus maximus, and the gastric cardia. The patient received 6 cycles of rituximab-bendamustine chemotherapy with a complete clinical and metabolic response at the 6-month follow-up PET/CT and remained relapse-free without visual acuity problem after a 36-month follow-up.
From the Departments of *Nuclear Medicine, †Oncology, and ‡Hematology, Lausanne University Hospital; §Jules Gonin Eye Hospital; ¶Department of Pathology, Lausanne University Hospital, Lausanne; and ∥Department of Oncology, Sion Hospital, Sion, Switzerland.
Asmaa
A
Sallak
Florent L
FL
Besson
Anastasia
A
Pomoni
Alexandre
A
Christinat
Marcel
M
Adler
Jean-Philippe
JP
Aegerter
Christophe
C
Nguyen
Laurence
L
de Leval
Valérie
V
Frossard
John O
JO
Prior
D000368:Aged; D003228:Conjunctiva / Q000000981:diagnostic imaging / Q000473:pathology; D003230:Conjunctival Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000000981:diagnostic imaging* / Q000473:pathology; D064847:Multimodal Imaging; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D051598:Whole Body Imaging
D019788:Fluorodeoxyglucose F18