Postural response latencies are related to balance control during standing and walking in patients with multiple sclerosis.
OBJECTIVE
To understand and examine the relation between postural response latencies obtained during postural perturbations and representative measures of balance during standing (sway variables) and walking (trunk motion).


METHODS
Cross-sectional.


METHODS
University medical center.


METHODS
Persons with multiple sclerosis (MS) (n=40) were compared with similar aged control subjects (n=20). There were 20 subjects with MS in the normal walking velocity group and 20 subjects with MS who had slow walking velocity based on a timed 25-foot walk (T25FW) of <5 seconds.


METHODS
None.


METHODS
Postural response latency, sway variables, trunk motion variables.


RESULTS
We found that subjects with MS with both slow or normal walking velocities had significantly longer postural response latencies than the healthy control group. Postural response latency was not correlated with the T25FW. Postural response latency was significantly correlated with center of pressure sway variables during quiet standing (root mean square: ρ=.334, P=.04; range: ρ=.385, P=.017; mean velocity: ρ=.337, P=.038; total sway area: ρ=.393, P=.015). Postural response latency was also significantly correlated with motion of the trunk during walking (sagittal plane range of motion: ρ=.316, P=.05; SD of transverse plane range of motion: ρ=-.43, P=.006).


CONCLUSIONS
These findings clearly indicate that slow postural responses to external perturbations in patients with MS contribute to disturbances in balance control during both standing and walking.
Landon Center on Aging, University of Kansas Medical Center, Kansas City, KS. Electronic address: jhuisinga@kumc.edu.
Jessie M
JM
Huisinga
Department of Neurology, Oregon Health and Science University, Portland, OR.
Rebecca J
RJ
St George
Department of Neurology, Oregon Health and Science University, Portland, OR; Neurology Department, Portland Veterans Affairs Medical Center, Portland, OR.
Rebecca
R
Spain
Department of Neurology, Oregon Health and Science University, Portland, OR.
Shannon
S
Overs
Department of Neurology, Oregon Health and Science University, Portland, OR.
Fay B
FB
Horak
D000046:Academic Medical Centers; D000328:Adult; D003430:Cross-Sectional Studies; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000503:physiopathology*; D026741:Physical Therapy Modalities; D004856:Postural Balance / Q000502:physiology*; D016138:Walking / Q000502:physiology*
Electromyography; Evoked potentials, somatosensory; Multiple sclerosis; Rehabilitation; Walking