Isoniazid-induced cerebellitis: a disguised presentation.
Cerebellitis is a rarely encountered complication of isoniazid therapy. Its occurrence is usually associated with concomitant renal disease and haemodialysis. Herein, we report the case of a patient with this complication who presented with isolated bilateral symmetrical dentate nucleus T2 hyperintensities on magnetic resonance imaging. Isoniazid neurotoxicity has never been reported to cause bilateral dentate hyperintensities, for which the differentials are few and include metronidazole toxicity.
Department of Radiodiagnosis, Christian Medical College and Hospital, Ludhiana, Punjab, Pin-141008, India. prasant.peter@rediffmail.com.
Prasant
P
Peter
Mary
M
John
D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects; D002526:Cerebellar Diseases / Q000139:chemically induced*; D002529:Cerebellar Nuclei / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D006435:Renal Dialysis; D051437:Renal Insufficiency / Q000628:therapy; D014376:Tuberculosis / Q000188:drug therapy
D000995:Antitubercular Agents; D007538:Isoniazid