Ageing and endurance training effects on quantity and quality of pulmonary vascular bed in healthy men.
It has recently been demonstrated that in healthy individuals, peak oxygen consumption is associated with a greater pulmonary capillary blood volume and a more distensible pulmonary circulation. Our cross-sectional study suggests that, in healthy men aged 20 to 60 years (n = 63), endurance sport practice (vigorous-intensity domain of the International Physical Activity Questionnaire) is associated with better quantity (pulmonary capillary blood volume) and quality (slope of increase in lung diffusion for carbon monoxide on exercise) of the pulmonary vascular bed, partly counterbalancing the deleterious effects of ageing, which remains to be demonstrated in a prospective longitudinal design.
Ghanima
G
Al Dandachi
Cécile
C
Londner
Aurore
A
Caumont-Prim
Laurent
L
Plantier
Brigitte
B
Chevalier-Bidaud
Jean-François
JF
Toussaint
François-Denis
FD
Desgorces
AP-HP, Hôpital européen Georges-Pompidou, Service de Physiologie - Clinique de la Dyspnée, 75015 Paris, France. christophe.delclaux@egp.aphp.fr.
Christophe
C
Delclaux
D000328:Adult; D000375:Aging / Q000502:physiology*; D003430:Cross-Sectional Studies; D015444:Exercise / Q000502:physiology*; D017079:Exercise Tolerance / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology*; D010807:Physical Endurance / Q000502:physiology*; D011446:Prospective Studies; D011652:Pulmonary Circulation / Q000502:physiology*; D011653:Pulmonary Diffusing Capacity / Q000502:physiology*; D011795:Surveys and Questionnaires; D055815:Young Adult