Optimizing the concentration of quaternary ammonium dimethacrylate monomer in bis-GMA/TEGDMA dental resin system for antibacterial activity and mechanical properties.
Four novel quaternary ammonium dimethacrylate monomers named IMQ (side alkyl chain length from 12 to 18) were synthesized with the aim to synthesize dental resin with antibacterial activity. All of IMQs were added into bis-GMA/TEGDMA dental resin system with a series of mass ratio (5, 10, and 20 wt%), double bond conversion (DC), flexural strength (FS), modulus of elasticity (FM) and biofilm formation inhibitory effect were studied. According to the results of DC, FS, FM, and the biofilm inhibitory effect, IMQ-16 containing polymer had the best comprehensive properties, and the optimal concentration of IMQ-16 in bis-GMA/TEGDMA dental resin would be in the range of 5-10 wt%.
College of Materials Science and Engineering, South China University of Technology, Guangzhou, 510641, China.
Xiaoxu
X
Liang
Eva
E
Söderling
Fang
F
Liu
Jingwei
J
He
Lippo V J
LV
Lassila
Pekka K
PK
Vallittu
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000737:chemistry; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects / Q000502:physiology; D019245:Compressive Strength; D004343:Drug Implants / Q000008:administration & dosage* / Q000737:chemistry; D055119:Elastic Modulus; D006244:Hardness; D008422:Materials Testing; D008689:Methacrylates / Q000008:administration & dosage / Q000138:chemical synthesis*; D011092:Polyethylene Glycols / Q000737:chemistry*; D011109:Polymethacrylic Acids / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage* / Q000138:chemical synthesis; D013295:Streptococcus mutans / Q000187:drug effects / Q000502:physiology*
D000900:Anti-Bacterial Agents; D004343:Drug Implants; D008689:Methacrylates; D011109:Polymethacrylic Acids; D000644:Quaternary Ammonium Compounds; C020946:triethylene glycol dimethacrylate; D011092:Polyethylene Glycols; D017438:Bisphenol A-Glycidyl Methacrylate