Comparison of rates of and charges from pregnancy complications in users of extended and cyclic combined oral contraceptive (COC) regimens: a brief report.
OBJECTIVE
To evaluate pregnancy complication rates and related charges in users of 84/7, 21/7 and 24/4 combined oral contraceptives (COCs).


METHODS
Data were obtained from the i3 InVision Data Mart™ retrospective claims database. Subjects were aged 15-40 years, first prescribed a COC between 1/1/2006 and 4/1/2011 and continuously insured for ≥1 year. 84/7 users were matched 1:1 to 21/7 and 24/4 users.


RESULTS
Pregnancy-related complication rates and associated charges were significantly lower with 84/7 vs. 21/7 and 24/4 regimens.


CONCLUSIONS
Preliminary data suggest 84/7 regimens may be associated with fewer pregnancy complications and lower related charges.
Teva Global Medical Affairs, Frazer, PA 19355, USA.
Brandon
B
Howard
Princeton University, Princeton, NJ 08544, USA; University of Hull, Hull HU6 7RX, England. Electronic address: trussell@princeton.edu.
James
J
Trussell
Teva Global Health Economics and Outcomes Research, Kansas City, MO 64131, USA.
ElizaBeth
E
Grubb
Health Metrics Outcomes Research, Bonita Springs, FL 34134, USA.
Maureen J
MJ
Lage
D000293:Adolescent; D000328:Adult; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage*; D005249:Fees and Charges / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000191:economics / Q000453:epidemiology*; D012189:Retrospective Studies; D014481:United States / Q000453:epidemiology; D055815:Young Adult
D003277:Contraceptives, Oral, Combined
84/7, 21/7, 24/4 regimens; Hormonal contraception; Pregnancy rates