Systematized linear epidermolytic hyperkeratosis.
A 5-year-old boy presented with widespread asymptomatic hyperpigmented verrucous plaques since 3 months of age. The lesions were distributed in a linear manner along Blaschko's lines on trunk and extremities and were accentuated in flexures and around joints. There was no history of blistering or redness and no other family member was affected. Ichthyosis hystrix (of Curth and Macklin) and generalized linear/mosaic epidermolytic hyperkeratosis (EHK) were considered in the differential diagnosis. Biopsy from both trunk lesion and lesion on knee revealed characteristic epidermolytic hyperkeratosis, thereby clinching the diagnosis of systematized linear EHK.
Katihar Medical College. docpiyush@gmail.com.
Piyush
P
Kumar
Rajesh
R
Kumar
Rajesh Kumar
RK
Mandal
Shahid
S
Hassan
D002675:Child, Preschool; D012628:Dermatitis, Seborrheic / Q000175:diagnosis; D003937:Diagnosis, Differential; D005799:Genes, Dominant; D006801:Humans; D017488:Hyperkeratosis, Epidermolytic / Q000145:classification / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D007057:Ichthyosis / Q000175:diagnosis; D007633:Keratins / Q000235:genetics; D008297:Male
D007633:Keratins