Gastrointestinal autonomic nerve tumor of the stomach.
METHODS
Female, 32 FINAL DIAGNOSIS: Gastrintestinal Autonomic Nerve Tumor (GANT) Symptoms: anemia • anorexia • fatigue • fever • hearburn • nausea • weight loss


METHODS
- Clinical Procedure: - Specialty: Gastroenterology and Hepatology.


OBJECTIVE
Rare disease.


BACKGROUND
Gastrointestinal autonomic nerve tumors (GANT) are extremely rare tumors that are related to gastrointestinal autonomic nervous plexuses. They are distinguished from stromal tumors by their unique ultrastructural features. Hence, their diagnosis is usually made on electron microscopy and immunohistochemical analyses. Although they are apparently slow-growing tumors, they run an aggressive clinical course and often associated with poor prognosis which eventually leads to death.


METHODS
We report on a case of gastric GANT in a young female who was treated surgically by total gastrectomy. The disease, however ran an aggressive course with the development of distant (nodal, liver, lung, adrenal and musculo-skeletal) metastases two months after the radical resection.


CONCLUSIONS
We believe this could be the first reported case of adrenal and musculo-skeletal metastases from gastric GANT soon after the radical gastric resection.
Section of General and Minimally Invasive Surgery, Department of Surgery, King Fahad Specialist Hospital, Dammam, Eastern Province, Saudi Arabia.
Abdul-Wahed N
AW
Meshikhes
Department of Pathology and Laboratory Medicine, King Fahad Specialist Hospital, Dammam, Eastern Province, Saudi Arabia.
Ayed A
AA
Al-Garni
Section of Gastroenterology, Department of Medicine, King Fahad Specialist Hospital, Dammam, Eastern Province, Saudi Arabia.
Sami A
SA
Al-Momen
Section of General and Minimally Invasive Surgery, Department of Surgery, King Fahad Specialist Hospital, Dammam, Eastern Province, Saudi Arabia.
Mamdouh
M
Al-Nahawi
Section of Gastroenterology, King Fahad Hospital, Hofouf, Saudi Arabia.
Jawad
J
Abu Subaih
gastrectomy; gastrointestinal autonomic nerve tumors; metastases; prognosis