Analysis of parameters for the automatic computation of the tear film break-up time test based on CCLRU standards.
Dry eye syndrome is affecting a remarkable percentage of population. The prevalence is 10-15% of normal population, and 18-30% of contact lenses users. The break-up time (BUT) is a clinical test used for the diagnosis of this disease. In this work, we perform an analysis of parameters for a global and a local automatic computation of the BUT measure, based on criteria of specificity and sensitivity. We have tested our methodology on a dataset composed of 18 videos annotated by 4 different experts. The local analysis preserves the results of the global approach providing useful additional information about the break-up tear zone.
VARPA Group, Department of Computer Science, University of A Coruña, Spain. Electronic address: l.ramos@udc.es.
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Ramos
VARPA Group, Department of Computer Science, University of A Coruña, Spain. Electronic address: nbarreira@udc.es.
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Barreira
Artificial Vision Group, Department of Electronics and Computer Science, University of Santiago de Compostela, Spain. Electronic address: antonio.mosquera@usc.es.
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Mosquera
VARPA Group, Department of Computer Science, University of A Coruña, Spain. Electronic address: mgpenedo@udc.es.
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Penedo
Optometry Group, Department of Applied Physics, University of Santiago de Compostela, Spain. Electronic address: eva.yebra-pimentel@usc.es.
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Yebra-Pimentel
Optometry Group, Department of Applied Physics, University of Santiago de Compostela, Spain. Electronic address: carlos.garcia.resua@rai.usc.es.
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García-Resúa
D000328:Adult; D000465:Algorithms; D019295:Computational Biology; D016208:Databases, Factual; D003936:Diagnosis, Computer-Assisted / Q000379:methods* / Q000592:standards / Q000706:statistics & numerical data; D003941:Diagnostic Techniques, Ophthalmological / Q000592:standards / Q000706:statistics & numerical data*; D015352:Dry Eye Syndromes / Q000175:diagnosis* / Q000503:physiopathology; D019793:Fluorescein; D005456:Fluorescent Dyes; D006801:Humans; D008856:Microscopy, Fluorescence; D018715:Microscopy, Video; D013666:Tears / Q000737:chemistry* / Q000502:physiology*; D055815:Young Adult
D005456:Fluorescent Dyes; D019793:Fluorescein
BUT test; Dry eye syndrome; Image processing; Tear film; Video analysis