Dietary proteins and angiogenesis.
Both defective and persistent angiogenesis are linked to pathological situations in the adult. Compounds able to modulate angiogenesis have a potential value for the treatment of such pathologies. Several small molecules present in the diet have been shown to have modulatory effects on angiogenesis. This review presents the current state of knowledge on the potential modulatory roles of dietary proteins on angiogenesis. There is currently limited available information on the topic. Milk contains at least three proteins for which modulatory effects on angiogenesis have been previously demonstrated. On the other hand, there is some scarce information on the potential of dietary lectins, edible plant proteins and high protein diets to modulate angiogenesis.
Department of Molecular and Biochemistry, University of Málaga, Málaga E-29071, Spain. medina@uma.es.
Miguel Ángel
MÁ
Medina
Department of Molecular and Biochemistry, University of Málaga, Málaga E-29071, Spain. quesada@uma.es.
Ana R
AR
Quesada
D000818:Animals; D004032:Diet; D004044:Dietary Proteins / Q000032:analysis*; D006801:Humans; D007781:Lactoferrin / Q000032:analysis; D037102:Lectins / Q000032:analysis; D008892:Milk / Q000737:chemistry; D008894:Milk Proteins / Q000032:analysis; D009389:Neovascularization, Pathologic; D010945:Plants, Edible / Q000737:chemistry; D030262:Soybean Proteins / Q000032:analysis
D004044:Dietary Proteins; D037102:Lectins; D008894:Milk Proteins; D030262:Soybean Proteins; D007781:Lactoferrin