Myofibroblastoma of the female breast with admixed but distinct foci of spindle cell lipoma: a case report.
Mammary myofibroblastoma (MFB) is a rare benign spindle neoplasm that affects both sexes with a male predominance. It can exhibit a wide range of histological patterns. We report a case of epithelioid/spindle MFB of the female breast with admixed, but distinct, foci of spindle cell lipoma. Whilst all the spindle cells within the tumour expressed CD34, AR, ER, BCL2, and CD10, only those within the myofibroblastoma expressed desmin and only those within the lipomatous areas expressed S100. This finding, to our knowledge, is a novel one that has not been reported before.
Department of Histopathology, Laboratory Block, Charing Cross Hospital Campus, Imperial College Healthcare NHS Trust and Imperial College, Fulham Palace Road, London W6 8RF, UK ; Department of Histopathology, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt.
Hazem A H
HA
Ibrahim
Department of Histopathology, Laboratory Block, Charing Cross Hospital Campus, Imperial College Healthcare NHS Trust and Imperial College, Fulham Palace Road, London W6 8RF, UK.
Sami
S
Shousha