Characterization of a new sesquiterpene and antifungal activities of chemical constituents from Dryopteris fragrans (L.) Schott.
One new sesquiterpene and six known compounds were isolated from Dryopteris fragrans (L.) Schot. They were identified as 3-O-β-D-glucopyranosylalbicanol- 11-O-β-D-glucopyranoside (1), dihydroconiferylalcohol (2), (E)-3-(4-hydroxyphenyl)acrylic acid (3), esculetin (4), 5,7-dihydroxy-2-hydroxymethylchromone (5), eriodictyol (6) and isoorientin (7) by UV, MS, 1D-NMR and 2D-NMR spectroscopy. The antifungal activities of the seven isolated compounds were screened. Compounds 2, 3, 4 and 5 showed obvious activities against Microsporum canis and Epidermophyton floccosum.
Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Science, Heilongiang University, Harbin 150080, China. YHHuanghd@163.com.
Yu-Hong
YH
Huang
Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Science, Heilongiang University, Harbin 150080, China. wmzenghd@163.com.
Wei-Min
WM
Zeng
Pharmaceutical College, Harbin Medical University, Harbin 150086, China. leegy@163.com.
Guo-Yu
GY
Li
Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Science, Heilongiang University, Harbin 150080, China. waterpowerful@sina.com.
Guo-Qing
GQ
Liu
Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Science, Heilongiang University, Harbin 150080, China. ddzhaohd@163.com.
Dan-Dan
DD
Zhao
Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Science, Heilongiang University, Harbin 150080, China. ebenbenebenben@sina.com.
Jing
J
Wang
Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Science, Heilongiang University, Harbin 150080, China. YLZhangHd@163.com.
Yan-Long
YL
Zhang
D000935:Antifungal Agents / Q000737:chemistry* / Q000494:pharmacology*; D032492:Dryopteris / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D012717:Sesquiterpenes / Q000737:chemistry* / Q000494:pharmacology*
D000935:Antifungal Agents; D010936:Plant Extracts; D012717:Sesquiterpenes