Enzyme-controllable F-NMR turn on through disassembly of peptide-based nanospheres for enzyme detection.
The enzyme tyrosinase could trigger the disassembly of peptide-based nanospheres, resulting in F-NMR signal turning on.
State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin 300071, P. R. China. yangzm@nankai.edu.cn.
Jie
J
Gao
Yang
Y
Shi
Youzhi
Y
Wang
Yanbin
Y
Cai
Jie
J
Shen
Deling
D
Kong
Zhimou
Z
Yang
D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005461:Fluorine / Q000737:chemistry / Q000378:metabolism; D051379:Mice; D008968:Molecular Conformation; D014442:Monophenol Monooxygenase / Q000032:analysis* / Q000378:metabolism*; D041681:NIH 3T3 Cells; D054118:Nanospheres / Q000737:chemistry* / Q000378:metabolism; D019906:Nuclear Magnetic Resonance, Biomolecular; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D013329:Structure-Activity Relationship
D010455:Peptides; D005461:Fluorine; D014442:Monophenol Monooxygenase