Study of tibial nerve regeneration in Wistar rats in primary neurorrhaphy with and without gap, wrapped in vein segments.
OBJECTIVE
This study compared nerve regeneration in Wistar rats, using epineural neurorrhaphy with a gap of 1.0 mm and without a gap, both wrapped with jugular vein tubes. Motor neurons in the spinal cord between L3 and S1 were used for the count, marked by exposure of the tibial nerve to Fluoro-Gold (FG).


METHODS
The tibial nerves on both sides were cut and sutured, with a gap on one side and no gap in the other. The sutures were wrapped with a jugular vein. Four months after surgery the tibial nerves were exposed to Fluoro-Gold and the motor neuron count performed in the spinal cord.


RESULTS
The results were statistically analyzed by the paired Wilcoxon test. There was a statistical difference between the groups with and without gap in relation to the motor neuron count (p=0.013).


CONCLUSIONS
The epineural neurorraphy without gap wrapped with jugular vein showed better results for nerve regeneration than the same procedure with gap.


METHODS
Experimental Study .
Universidade Federal de São Paulo (UNIFESP) - São Paulo, SP, Brazil.
Ewerton
E
Bastos Dos Santos
Universidade Federal de São Paulo (UNIFESP) - São Paulo, SP, Brazil.
Marcela
M
Fernandes
Universidade Federal de São Paulo (UNIFESP) - São Paulo, SP, Brazil.
João Baptista
JB
Gomes Dos Santos
Universidade Federal de São Paulo (UNIFESP) - São Paulo, SP, Brazil.
Vilnei
V
Mattioli Leite
Universidade Federal de São Paulo (UNIFESP) - São Paulo, SP, Brazil.
Sandra Gomes
SG
Valente
Universidade Federal de São Paulo (UNIFESP) - São Paulo, SP, Brazil.
Flávio
F
Faloppa
Fluorescent dyes; Nerve regeneration; Suture techniques; Tibial nerve; Wistar rats