On the non-linear attachment characteristics of blood to bacterial cellulose/kaolin biomaterials.
In this communication, we report a non-linear variation in the strength of blood attachment to bacterial cellulose/kaolin biomaterials as the fractions of bacterial cellulose to kaolin are increased. The changes observed for attachment strength are elucidated following both experimental and numerical investigations on both the biomaterial and the blood-biomaterial interface. Our research reveals that the non-linear strength of attachment of blood is related to topographical characteristics on the surface of the biomaterial, the maleability of the biomaterial and the intermolecular strength of attraction between clotted blood proteins (fibrinogen) with the cellulose/kaolin components of the biomaterial.
Laboratory of Paper Coating and Converting, Centre for Functional Materials, Abo Akademi University, Porthaninkatu 3, 20500 Turku, Finland.
Diosángeles Soto
DS
Véliz
Department of Biosciences, Cell Biology, Abo Akademi University, Biocity, Tykistökatu 6, Turku, Finland.
Catharina
C
Alam
Department of Biosciences, Cell Biology, Abo Akademi University, Biocity, Tykistökatu 6, Turku, Finland.
Diana M
DM
Toivola
Laboratory of Paper Coating and Converting, Centre for Functional Materials, Abo Akademi University, Porthaninkatu 3, 20500 Turku, Finland.
Martti
M
Toivakka
Laboratory of Paper Coating and Converting, Centre for Functional Materials, Abo Akademi University, Porthaninkatu 3, 20500 Turku, Finland. Electronic address: parvez.alam@abo.fi.
Parvez
P
Alam
D000091:Acetobacter / Q000737:chemistry*; D000818:Animals; D002482:Cellulose / Q000097:blood / Q000737:chemistry*; D005340:Fibrinogen / Q000737:chemistry; D007616:Kaolin / Q000097:blood / Q000737:chemistry*; D051379:Mice; D008815:Mice, Inbred Strains; D056004:Molecular Dynamics Simulation
D007616:Kaolin; D005340:Fibrinogen; D002482:Cellulose
Adhesion; Bacterial cellulose; Blood; Kaolin; Tribology; Wound