Ruthenium-catalyzed ortho-arylation of acetanilides with aromatic boronic acids: an easy route to prepare phenanthridines and carbazoles.
The highly regioselective ortho-arylation of acetanilides with aromatic boronic acids in the presence of a Ru(II) complex (3 mol%), AgSbF6 (12 mol%), Cu(OTf)2 (20 mol%) and Ag2O (1.0 eq.) is described. Later, ortho-arylated acetanilides were converted into phenanthridine and carbazole derivatives by using Ph3PO and Tf2O or palladium or Cu(OTf)2 catalysts.
Department of Chemistry, Indian Institute of Science Education and Research, Pune 411021, India. mjeganmohan@iiserpune.ac.in.
Ravi Kiran
RK
Chinnagolla
Masilamani
M
Jeganmohan