Laparoscopic management of hypertrophic hypersecretory gastropathy with protein loss: a case report.
Hypertrophic hypersecretory gastropathy with protein loss (HHGP) is a rare form of acquired gastropathy characterized by giant gastric rugal folds and hypoalbuminemia. It is often misdiagnosed as Ménétrier's disease. We report the case of a 45-year-old man with HHGP who presented with nausea and anorexia. The patient had no underlying disease and was not on medication. Esophagogastroduodenoscopy and CT showed a thickening of the gastric folds in the stomach. As cancer cells were not detected on endoscopic biopsies, the patient was diagnosed with Ménétrier's disease. He was managed with a high-protein diet and annual follow-up by esophagogastroduodenoscopy. Five years after the diagnosis, the patient underwent laparoscopy-assisted total gastrectomy for refractory abdominal pain, diarrhea, and protein loss. A pathological diagnosis of HHGP was made and he was discharged without any surgical complications. The patient was relieved of anorexia, abdominal pain, and diarrhea. Laparoscopy-assisted total gastrectomy could be regarded as a treatment option for HHGP.
Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Jeik
J
Byun
Sebastianus
S
Kwon
Seung-Young
SY
Oh
Kyung-Goo
KG
Lee
Yun-Suhk
YS
Suh
Seong-Ho
SH
Kong
Sang-Gyun
SG
Kim
Woo-Ho
WH
Kim
Han-Kwang
HK
Yang
Hyuk-Joon
HJ
Lee
D005743:Gastrectomy / Q000379:methods*; D005758:Gastritis, Hypertrophic / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D034141:Hypoalbuminemia / Q000209:etiology*; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged
Hypertrophic hypersecretory gastropathy with protein loss; laparoscopic surgery; laparoscopy-assisted total gastrectomy