Management of juvenile gender dysphoria.
OBJECTIVE
To describe the treatment of gender dysphoria in adolescents.


RESULTS
Careful study and evaluation of children with persistent severe gender dysphoria has led to the recommendation that puberty be suppressed at Tanner Stage II. If the dysphoria persists until age 16, treatment with sex steroids of the appropriate gender may begin at age 16 and be followed by gender-appropriate surgery.


CONCLUSIONS
Protocols and results of treatment of early adolescents have demonstrated that the harmful effects of persistent gender dysphoria can be prevented. Pubertal suppression in early puberty not only prevents the severe distress, but also allows healthy adolescent development living in the appropriate gender.
Columbia University College of Physicians and Surgeons, New York, New York, USA.
Wylie C
WC
Hembree
D000293:Adolescent; D000294:Adolescent Behavior; D016497:Adolescent Health Services; D002648:Child; D005260:Female; D005783:Gender Identity; D012739:Gonadal Steroid Hormones / Q000627:therapeutic use*; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D017410:Practice Guidelines as Topic; D011627:Puberty / Q000187:drug effects* / Q000523:psychology; D057829:Gender-Affirming Procedures / Q000379:methods*; D013997:Time Factors; D014189:Transsexualism / Q000523:psychology / Q000628:therapy*; D057832:Watchful Waiting
D012739:Gonadal Steroid Hormones; D007987:Gonadotropin-Releasing Hormone