Synthesis of benzannulated heterocycles by twofold Suzuki-Miyaura couplings of cyclic diarylborinic acids.
Two-fold Suzuki-Miyaura cross-couplings of cyclic diarylborinic acids are described. This novel annulation method enables the synthesis of benzo-fused heterocycles from dihaloarenes or gem-dibromoolefins.
Department of Chemistry, University of Toronto, 80 St. George St., Toronto, ON M5S 3H6, Canada. mtaylor@chem.utoronto.ca.
Elena
E
Dimitrijević
Madeline
M
Cusimano
Mark S
MS
Taylor