Gastro-oesophageal reflux and cough.
Gastro-oesophageal reflux, either singly or in association with postnasal drip and/or asthma is considered to be a cause of chronic cough. The amount and nature of gastro-oesophageal reflux however is often normal with acid suppression having very little, if any therapeutic effect in these patients. This review examines the challenges posed when exploring the reflux-cough link, and discusses the merits and limitations of the proposed mechanisms of reflux leading to cough.
Respiratory and Allergy Centre, The University of Manchester, University Hospital of South Manchester, Manhester, UK.
Rayid
R
Abdulqawi
Division of Gastroenterology and Hepatology, Mayo Clinic, Florida, USA.
Lesley A
LA
Houghton
Respiratory and Allergy Centre, The University of Manchester, University Hospital of South Manchester, Manhester, UK.
Jaclyn A
JA
Smith
D002908:Chronic Disease; D003371:Cough / Q000209:etiology* / Q000503:physiopathology*; D005764:Gastroesophageal Reflux / Q000150:complications*; D006801:Humans; D012018:Reflex