Effects of the novel poly(methyl methacrylate) (PMMA)-encapsulated organic ultraviolet (UV) filters on the UV absorbance and in vitro sun protection factor (SPF).
Sunscreens are thought to protect skin from many of the harmful effects of ultraviolet (UV) light and the photostability of sunscreens is thus an important concern in their application. Therefore, to discover new UV filters or to modify well-known UV filters are presents an important way for development of sunscreens. In this study, we presented several novel poly(methyl methacrylate) (PMMA) encapsulated organic UV filters, including encapsulated benzophenone-3 (TB-MS), avobenzone (TA-MS), octyl methoxycinnamate (TO-MS) and diethylamino hydroxybenzoyl hexyl benzoate (TD-MS). Our results have demonstrated that PMMA-encapsulated UV filters have improved safety, photoprotective ability and photostability. We proposed therefore that these PMMA-encapsulated UV filters can be used as ingredients for sunscreen products in the future.
Department of Cosmetic Science, Providence University, No. 200, Sec. 7, Taiwan Boulevard, Shalu, Taichung 43301, Taiwan, ROC.
Pey-Shiuan
PS
Wu
Department of Cosmetic Science, Providence University, No. 200, Sec. 7, Taiwan Boulevard, Shalu, Taichung 43301, Taiwan, ROC.
Lan-Ni
LN
Huang
Department of Cosmetic Science, Providence University, No. 200, Sec. 7, Taiwan Boulevard, Shalu, Taichung 43301, Taiwan, ROC.
Yi-Cing
YC
Guo
Department of Cosmetic Science, Providence University, No. 200, Sec. 7, Taiwan Boulevard, Shalu, Taichung 43301, Taiwan, ROC. Electronic address: chchlin@pu.edu.tw.
Chih-Chien
CC
Lin
D000627:Aminophenols / Q000737:chemistry; D000818:Animals; D001577:Benzophenones / Q000737:chemistry; D045744:Cell Line, Tumor / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002934:Cinnamates / Q000737:chemistry / Q000493:pharmacokinetics; D004353:Drug Evaluation, Preclinical / Q000379:methods; D066298:In Vitro Techniques; D008545:Melanoma / Q000188:drug therapy / Q000473:pathology; D051379:Mice; D019904:Polymethyl Methacrylate / Q000737:chemistry*; D011427:Propiophenones / Q000737:chemistry / Q000493:pharmacokinetics; D012867:Skin / Q000187:drug effects; D013056:Spectrophotometry, Ultraviolet; D059405:Sun Protection Factor; D013473:Sunscreening Agents / Q000737:chemistry* / Q000493:pharmacokinetics / Q000494:pharmacology*; D013552:Swine; D014466:Ultraviolet Rays
D000627:Aminophenols; D001577:Benzophenones; D002934:Cinnamates; D011427:Propiophenones; D013473:Sunscreening Agents; C118580:octylmethoxycinnamate; D019904:Polymethyl Methacrylate; C000597744:diethylamino hydroxybenzoyl hexyl benzoate; C049935:avobenzone
Encapsulated ultraviolet (UV) filters; Photostability; Poly(methyl methacrylate) (PMMA); Sun protection factor (SPF); UV absorbance