[Baclofen and other GABAB receptor agents are allosteric modulators of the CXCL12 chemokine receptor CXCR4].
Institut de pharmacologie moléculaire et cellulaire (IPMC), UMR 7275 CNRS/Université Nice Sophia Antipolis, 660, route des Lucioles, ZA Sophia Antipolis, 06560 Valbonne, France.
Alice
A
Guyon
D000494:Allosteric Regulation / Q000187:drug effects; D000818:Animals; D001418:Baclofen / Q000378:metabolism / Q000494:pharmacology*; D045744:Cell Line, Tumor; D054377:Chemokine CXCL12 / Q000378:metabolism / Q000494:pharmacology; D002633:Chemotaxis / Q000187:drug effects; D058786:GABA-B Receptor Agonists / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D009369:Neoplasms / Q000473:pathology; D011485:Protein Binding; D019718:Receptors, CXCR4 / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism; D014981:Xenopus
D054377:Chemokine CXCL12; D058786:GABA-B Receptor Agonists; D019718:Receptors, CXCR4; D001418:Baclofen