Regioselective C2 sulfonylation of indoles mediated by molecular iodine.
A facile and general method for regioselective C2 sulfonylation reaction of indoles mediated by iodine is described. The 2-sulfonylated products were obtained up to 96% yield under mild reaction conditions (room temperature, 2 h).
Department of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University , Rama VI Road, Bangkok 10400, Thailand.
Praewpan
P
Katrun
Charoensak
C
Mueangkaew
Manat
M
Pohmakotr
Vichai
V
Reutrakul
Thaworn
T
Jaipetch
Darunee
D
Soorukram
Chutima
C
Kuhakarn
D007211:Indoles / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis* / Q000737:chemistry*
D007211:Indoles; D013438:Sulfhydryl Compounds; D007455:Iodine