[Genomic medicine: the new way of thinking medicine present and future--Part two].
New sequencing techniques are revolutionizing medical practice as its applications are numerous and considerable. We are living a technological turning point in molecular medicine. Indeed, thanks to these new machines, this technological leap allowed us to analyse the human genome with an elarged or even a total view. Genome analysis has applications in all medical fields from now on. Gene analysis in parallel with personalized therapy help in prolonged survival or even cures in some cancers or other diseases. Genetics is progressively arriving in every field of clinical practice. A new way of thinking clinics is born. This publication describes in its main lines these new applications, their problems and their challenges for geneticists as much as for other practitioners in the medical fields.
Département de génétique moléculaire, Hôpital Bichat, Hôpitaux Universitaires Paris Nord Val de Seine, Paris, France.
Jérôme
J
Lamoril
Laboratoire de biologie, Centre hospitalier d'Argenteuil, France.
Marc
M
Bogard
D059472:Exome; D015894:Genome, Human; D023281:Genomics / Q000191:economics / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D059014:High-Throughput Nucleotide Sequencing / Q000191:economics / Q000295:instrumentation / Q000379:methods; D006801:Humans; D007755:Laboratories, Hospital / Q000639:trends; D058990:Molecular Targeted Therapy / Q000191:economics / Q000379:methods / Q000639:trends; D057285:Precision Medicine / Q000191:economics / Q000295:instrumentation / Q000379:methods* / Q000639:trends*
Sanger; genomics; human genome; sequencing