Comparison of local features from two Spanish hospitals reveals common and specific traits at multiple levels of the molecular epidemiology of metallo-β-lactamase-producing Pseudomonas spp.
Twenty-seven well-characterized metallo-β-lactamase (MBL)-producing Pseudomonas strains from two distantly located hospitals were analyzed. The results revealed specific features defining the multilevel epidemiology of strains from each hospital in terms of species, clonality, predominance of high-risk clones, composition/diversity of integrons, and linkages of Tn402-related structures. Therefore, despite the global trends driving the epidemiology of MBL-producing Pseudomonas spp., the presence of local features has to be considered in order to understand this threat and implement proper control strategies.
Servicio de Microbiología, Hospital Universitario 12 de Octubre, Madrid, Spain.
Esther
E
Viedma
Vanesa
V
Estepa
Carlos
C
Juan
Jane
J
Castillo-Vera
Beatriz
B
Rojo-Bezares
Cristina
C
Seral
Francisco Javier
FJ
Castillo
Yolanda
Y
Sáenz
Carmen
C
Torres
Fernando
F
Chaves
Antonio
A
Oliver
D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D006761:Hospitals / Q000706:statistics & numerical data; D017720:Molecular Epidemiology; D011549:Pseudomonas / Q000201:enzymology* / Q000235:genetics; D013030:Spain; D001618:beta-Lactamases / Q000378:metabolism*
D001618:beta-Lactamases