Vaccine against scabies: necessity and possibility.
Scabies is an infectious disease that is endemic in poorly resourced communities, and also common in industrialized countries. Although the disease, which is caused by infestation of Sarcoptes scabiei, is generally mild, the need for a vaccine against S. scabiei is proposed. The immunological mechanisms that control S. scabiei infection are discussed and the current status of scabies vaccine development reviewed. Future directions for scabies vaccine development are also addressed.
Inflammation and Healing Research Cluster, Faculty of Science, Health, Education and Engineering, School of Health and Sport Sciences, University of Sunshine Coast, Locked Bag 4, Marcoochydore DC, QLD 4558, Australia.
Xiaosong
X
Liu
Inflammation and Healing Research Cluster, Faculty of Science, Health, Education and Engineering, School of Health and Sport Sciences, University of Sunshine Coast, Locked Bag 4, Marcoochydore DC, QLD 4558, Australia.
Shelley
S
Walton
Inflammation and Healing Research Cluster, Faculty of Science, Health, Education and Engineering, School of Health and Sport Sciences, University of Sunshine Coast, Locked Bag 4, Marcoochydore DC, QLD 4558, Australia.
Kate
K
Mounsey
D000818:Animals; D006801:Humans; D012520:Sarcoptes scabiei / Q000276:immunology*; D012532:Scabies / Q000276:immunology* / Q000517:prevention & control; D014612:Vaccines / Q000276:immunology*
D014612:Vaccines