Nosocomial outbreak of Salmonella enterica serovar Typhimurium primarily affecting a pediatric ward in South Africa in 2012.
We describe a nosocomial outbreak of diarrheal disease caused by extended-spectrum β-lactamase-producing multidrug-resistant Salmonella enterica serovar Typhimurium, focused on a pediatric ward in South Africa. The outbreak peaked between May 2012 and July 2012. Person-to-person transmission was the most likely mechanism of spread of the infection, expedited due to a breakdown in hand-washing and hygiene, suboptimal infection control practices, overcrowding of hospital wards, and an undesirable nurse-to-patient ratio.
Centre for Enteric Diseases, National Institute for Communicable Diseases, Division in the National Health Laboratory Service, Johannesburg, South Africa.
Anthony M
AM
Smith
Mnikelwa A
MA
Mthanti
Carel
C
Haumann
Nomalungisa
N
Tyalisi
Gerald P G
GP
Boon
Arvinda
A
Sooka
Karen H
KH
Keddy
D000328:Adult; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology* / Q000635:transmission; D003967:Diarrhea / Q000453:epidemiology / Q000382:microbiology; D004196:Disease Outbreaks; D006761:Hospitals; D006801:Humans; D007223:Infant; D012480:Salmonella Infections / Q000453:epidemiology* / Q000382:microbiology* / Q000635:transmission; D012486:Salmonella typhimurium / Q000201:enzymology / Q000302:isolation & purification*; D013019:South Africa; D001618:beta-Lactamases / Q000378:metabolism
D001618:beta-Lactamases