Psychiatric sequelae of organophosphorous poisoning: a case study and review of the literature.
This is the case of a young farm worker presenting with episodes of acute organic psychosis superimposed on a state of chronic anergy and hypersomnia. It is suggested that he developed an encephalopathic illness presenting with an organic bipolar affective disorder as a result of organophosphate exposure. In proposing this aetiology, an hypothesis is developed which links clinical observations and investigative results with research findings in relation to organophosphorus compounds and neuropharmacology.
Department of Psychiatry, Doncaster Royal Infirmary, Doncaster, UK.
R H
RH
Bradwell
Hypersensitivity; Lithium; Neurotoxicity; Organic bipolar affective disorder; Organophosphorous; Phosphoinositide