Diversity, abundance and natural products of marine sponge-associated actinomycetes.
Actinomycetes are known for their unprecedented ability to produce novel lead compounds of clinical and pharmaceutical importance. This review focuses on the diversity, abundance and methodological approaches targeting marine sponge-associated actinomycetes. Additionally, novel qPCR data on actinomycete abundances in different sponge species and other environmental sources are presented. The natural products literature is covered, and we are here reporting on their chemical structures, their biological activities, as well as the source organisms from which they were isolated.
Department of Botany II, Julius-von-Sachs-Institute for Biological Sciences, University of Würzburg, Julius-von-Sachs-Platz 3, 97082 Würzburg, Germany. usama.ramadan@uni-wuerzburg.de.
Usama Ramadan
UR
Abdelmohsen
Kristina
K
Bayer
Ute
U
Hentschel
D039903:Actinobacteria / Q000737:chemistry*; D000818:Animals; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification; D008386:Marine Biology; D015394:Molecular Structure; D011161:Porifera / Q000382:microbiology*
D001688:Biological Products