Antimicrobial resistance in eight US hospitals along the US-Mexico border, 2000-2006.
Antimicrobial resistance (AR) is a growing problem worldwide and international travel, cross-border migration, and antimicrobial use may contribute to the introduction or emergence of AR. We examined AR rates and trends along the US-Mexico border by analysing microbiology data from eight US hospitals in three states bordering Mexico. Microbiology data were ascertained for the years 2000-2006 and for select healthcare and community pathogens including, three Gram-negative (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae) and three Gram-positive (Staphylococcus aureus, Enterococcus, Streptococcus pneumoniae) pathogens and 10 antimicrobial-pathogen combinations. Resistance was highest in S. aureus (oxacillin resistance 45·7%), P. aeruginosa (quinolone resistance 22·3%), and E. coli (quinolone resistance 15·6%); six (60%) of the 10 antimicrobial-pathogen combinations studied had a significantly increasing trend in resistance over the study period. Potential contributing factors in the hospital and community such as infection control practices and antimicrobial use (prescription and non-prescription) should be explored further in the US-Mexico border region.
Division of Healthcare Quality Promotion,National Center For Emerging & Zoonotic Infectious Diseases,CDC, Atlanta, GA,USA.
S R
SR
Benoit
Division of Healthcare Quality Promotion,National Center For Emerging & Zoonotic Infectious Diseases,CDC, Atlanta, GA,USA.
K D
KD
Ellingson
Division of Global Migration And Quarantine,National Center For Emerging & Zoonotic Infectious Diseases,CDC, Atlanta, GA,USA.
S H
SH
Waterman
Division of Tuberculosis Elimination,National Center for HIV/AIDS,Viral Hepatitis, STD & TB Prevention, CDC, Atlanta, GA,USA.
M L
ML
Pearson
D000890:Anti-Infective Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology*; D006786:Hospitals, Urban; D006801:Humans; D015994:Incidence; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D012189:Retrospective Studies; D018570:Risk Assessment; D014481:United States / Q000453:epidemiology
D000890:Anti-Infective Agents