Alkylation of terminal alkynes with transient σ-alkylpalladium(II) complexes: a carboalkynylation route to alkyl-substituted alkynes.
A mild and general alkylation of terminal alkynes with transient σ-alkylpalladium(II) complexes for assembling alkyl-substituted alkynes is described. This method represents a new way to the use of transient σ-alkylpalladium(II) complexes in organic synthesis through 1,2-carboalkynylation of alkenes.
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082 (China), Fax: (+86) 731-8871-3642.
Ming-Bo
MB
Zhou
Xiao-Cheng
XC
Huang
Yan-Yun
YY
Liu
Ren-Jie
RJ
Song
Jin-Heng
JH
Li
D000475:Alkenes / Q000737:chemistry; D000478:Alkylation; D000480:Alkynes / Q000737:chemistry*; D056831:Coordination Complexes / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
D000475:Alkenes; D000480:Alkynes; D056831:Coordination Complexes; D010165:Palladium
4-(o-haloaryl)alkenes; alkylation; alkynes; carboalkynylation; palladium