Cholesterol-lowering Effect of Rice Protein by Enhancing Fecal Excretion of Lipids in Rats.
The aim of this study was to investigate the effects of isolated protein from white rice on lipid metabolism in a hypercholesterolemic animal model. Male Sprague-Dawley rats were divided into three groups and fed either a normal diet or a high-cholesterol diet (HCD) containing either casein or isolated rice protein for 4 weeks. Compared with rats fed a HCD with casein, the total cholesterol (TC) level in the plasma was significantly reduced in the rats fed rice protein. However, no significant differences were observed in the triglycerides, high-density lipoprotein (HDL), and glucose levels among the experimental groups. Hepatic total lipids and TC levels were significantly decreased by supplementation with rice protein. In addition, rice protein significantly increased the levels of TC and bile acids in the feces. These results suggest that rice protein may improve HCD-induced hypercholesterolemia by enhancing fecal excretion of cholesterol.
Nutrition and Metabolism Research Group, Korea Food Research Institute, Gyeonggi 463-746, Korea.
Min Young
MY
Um
Nutrition and Metabolism Research Group, Korea Food Research Institute, Gyeonggi 463-746, Korea.
Jiyun
J
Ahn
Nutrition and Metabolism Research Group, Korea Food Research Institute, Gyeonggi 463-746, Korea.
Chang Hwa
CH
Jung
Nutrition and Metabolism Research Group, Korea Food Research Institute, Gyeonggi 463-746, Korea.
Tae Youl
TY
Ha
cholesterol; fecal fat; rice protein