Efficacy of intra-arterial treatment for massive gastrointestinal bleeding in hemodialysis patients.
The incidence of acute nonvariceal massive gastrointestinal bleeding (GIB) is higher in hemodialysis (HD) patients than in healthy individuals, and this is often a life-threatening event. We evaluated the efficacy of intra-arterial treatment for GIB in HD patients. Between January 2006 and June 2012, eight HD patients with GIB were treated with superselective transarterial embolization. Of the eight cases, one was duodenal bleeding, two were jejunal bleeding, one was ileocecum bleeding, two were ascending colonic bleeding, and two were sigmoid colonic bleeding. After examining the site of bleeding by endoscopy or contrast-enhanced computed tomography (CT), embolizations with microcoils, gelatin sponges, or N-butyl cyanoacrylate were performed through interventional radiology (IVR). In all cases, blood transfusions were frequently administered. Six of the eight patients with GIB were successfully salvaged by transarterial embolization. In one case, duodenal bleeding was refractory to endoscopic treatment. Embolization was performed twice in this case; however, the patient died of an aneurysm rupture at the embolization site 24 days after the embolizations. In another case, massive jejunal bleeding and disseminated intravascular coagulation were identified at the time of the first examination, and the patient died of multiorgan failure 26 days after the embolization. On the basis of our experience, we established an effective treatment strategy for HD patients with acute nonvariceal massive GIB, by immediately identifying the exact site and degree of bleeding using contrast-enhanced computed tomography and performing early treatment with transarterial embolization.
Department of Artificial Organs, Akane-Foundation, Tsuchiya General Hospital, Hiroshima, Japan.
Masataka
M
Banshodani
Hideki
H
Kawanishi
Misaki
M
Moriishi
Sadanori
S
Shintaku
Tomoyasu
T
Sato
Shinichiro
S
Tsuchiya
D000208:Acute Disease; D000328:Adult; D000368:Aged; D001803:Blood Transfusion; D003287:Contrast Media; D004621:Embolization, Therapeutic / Q000379:methods*; D004724:Endoscopy / Q000379:methods; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012189:Retrospective Studies; D016879:Salvage Therapy / Q000379:methods / Q000451:nursing; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D003287:Contrast Media
Gastrointestinal bleeding; Hemodialysis; Interventional radiology; Intra-arterial treatment; Transarterial embolization