Congenital Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor: A Case Report and Review of the Literature.
Ewing's sarcoma (EWS) and peripheral primitive neuroectodermal tumor (pPNET) are small round cell malignancies that develop in soft tissue and bone. They very rarely affect newborns. A diagnosis of EWS/pPNET depends mainly on immunohistochemistry and molecular/genetic assays. Since these tumors are highly aggressive, patient prognosis is typically very poor, and treatment remains a challenge. Here, we report a 13-day-old newborn diagnosed with congenital EWS/pPNET and describe its treatment.
Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu 610041, China. Electronic address: shgjin2003@aliyun.com.
Shu-Guang
SG
Jin
Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.
Xiao-Ping
XP
Jiang
Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.
Lin
L
Zhong
D001859:Bone Neoplasms / Q000151:congenital* / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007231:Infant, Newborn; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000151:congenital* / Q000473:pathology* / Q000628:therapy; D012512:Sarcoma, Ewing / Q000151:congenital* / Q000473:pathology* / Q000628:therapy
Ewing's sarcoma; diagnosis; newborn; peripheral primitive neuroectodermal tumor; prognosis; treatment