Effects of folic acid and vitamin B12 supplementation on culling rate, diseases, and reproduction in commercial dairy herds.
This study was undertaken to determine the effect of a combined folic acid and vitamin B12 supplement given in early lactation on culling rate, metabolic disorders and other diseases, and reproduction in commercial dairy herds. A total of 805 cows (271 primiparous and 534 multiparous cows) in 15 commercial dairy herds were involved. Every 2mo from February to December 2010 and within each herd, cows were assigned according to parity, previous 305-d milk production, and calving interval to 5mL of either (1) saline 0.9% NaCl (control group) or (2) 320mg of folic acid + 10mg of vitamin B12 (vitamin group). Treatments were administered weekly by intramuscular injections starting 3wk before the expected calving date until 8wk after parturition. A total of 221 cows were culled before the next dry period. Culling rate was not affected by treatment and was 27.5%; culling rate was greater for multiparous (32.2%) than for primiparous cows (18.8%). Within the first 60d in milk (DIM), 47 cows were culled, representing 21.3% of total culling, and no treatment effect was noted. Ketosis incidence based on a threshold ≥100µmol/L of β-hydroxybutyrate in milk was 38.3±2.9% for the vitamin group and 41.8±3.0% for the control group and was not affected by treatment. The combined supplement of folic acid and vitamin B12 did not decrease incidence of retained placenta, displaced abomasum, milk fever, metritis, or mastitis. However, the incidence of dystocia decreased by 50% in multiparous cows receiving the vitamin supplement, although no effect was observed in primiparous cows. The first breeding postpartum for multiparous cows occurred 3.8d earlier with the vitamin supplement compared with controls, whereas no treatment effect was seen for primiparous cows. Days open, first- and second-breeding conception rates, number of breedings per conception, and percentage of cows pregnant at 150 DIM were not affected by treatment. The reduced percentage of dystocia combined with the earlier DIM at first breeding for multiparous cows receiving the combined supplementation in folic acid and vitamin B12 indicates that the vitamin supplement had a positive effect in older cows.
Département des Sciences Animales, Université Laval, Québec, G1V 0A6, Canada; Agriculture et Agroalimentaire Canada, Centre de recherche et développement sur le bovin laitier et le porc, Sherbrooke, Québec, J1M 0C8, Canada.
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M
Duplessis
Agriculture et Agroalimentaire Canada, Centre de recherche et développement sur le bovin laitier et le porc, Sherbrooke, Québec, J1M 0C8, Canada. Electronic address: Christiane.Girard@agr.gc.ca.
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CL
Girard
Valacta, Ste-Anne-de-Bellevue, Québec, H9X 3R4, Canada.
D E
DE
Santschi
Département des Sciences Animales, Université Laval, Québec, G1V 0A6, Canada.
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JP
Laforest
Valacta, Ste-Anne-de-Bellevue, Québec, H9X 3R4, Canada.
J
J
Durocher
Département des Sciences Animales, Université Laval, Québec, G1V 0A6, Canada.
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D
Pellerin
D020155:3-Hydroxybutyric Acid / Q000097:blood; D065136:Animal Culling; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control*; D019587:Dietary Supplements; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage*; D015994:Incidence; D007662:Ketosis / Q000517:prevention & control / Q000662:veterinary; D007774:Lactation; D008414:Mastitis, Bovine / Q000517:prevention & control; D008892:Milk / Q000737:chemistry; D010298:Parity; D010319:Parturient Paresis / Q000517:prevention & control; D018457:Placenta, Retained / Q000517:prevention & control / Q000662:veterinary; D011247:Pregnancy; D012098:Reproduction / Q000187:drug effects*; D014805:Vitamin B 12 / Q000008:administration & dosage*
D005492:Folic Acid; D014805:Vitamin B 12; D020155:3-Hydroxybutyric Acid
commercial herds; dairy cow; folic acid; vitamin B(12)