Sub-MIC levels of purpurin inhibit membrane ATPase-mediated proton efflux activity in the human fungal pathogen Candida albicans.
Oral BioSciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China.
Paul Wai-Kei
PW
Tsang
Oral BioSciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China.
Alan Pak-Kin
AP
Wong
Oral BioSciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China.
Han-Sung
HS
Jung
School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Wing-Ping
WP
Fong
D000880:Anthraquinones / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects* / Q000201:enzymology / Q000254:growth & development; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005656:Fungal Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D049990:Membrane Transport Modulators / Q000494:pharmacology*; D009994:Osmolar Concentration; D006180:Proton-Translocating ATPases / Q000037:antagonists & inhibitors* / Q000378:metabolism
D000880:Anthraquinones; D000935:Antifungal Agents; D004791:Enzyme Inhibitors; D005656:Fungal Proteins; D049990:Membrane Transport Modulators; D006180:Proton-Translocating ATPases; C511975:purpurin anthraquinone