Associations between polymorphisms of LSAMP gene and schizophrenia.
The purpose of this study was to explore relationships between single-nucleotide polymorphisms (SNPs) in the limbic system-associated membrane protein (LSAMP) gene and schizophrenia. Twenty-two SNPs were analysed in 127 unrelated schizophrenic patients and in 171 healthy controls. The results showed significant allelic and haplotypic associations between LSAMP gene and schizophrenia.
Institute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia; Centre of Excellence for Translational Medicine, University of Tartu, Tartu, Estonia. Electronic address: kati.koido@ut.ee.
Kati
K
Koido
Department of Psychiatry, University of Tartu, Tartu, Estonia.
Sven
S
Janno
Institute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia; Centre of Excellence for Translational Medicine, University of Tartu, Tartu, Estonia.
Tanel
T
Traks
Department of Psychiatry, University of Tartu, Tartu, Estonia.
Madis
M
Parksepp
Department of Psychiatry, University of Tartu, Tartu, Estonia.
Ülle
Ü
Ljubajev
Department of Psychiatry, University of Tartu, Tartu, Estonia.
Peeter
P
Veiksaar
Institute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia; Centre of Excellence for Translational Medicine, University of Tartu, Tartu, Estonia.
Anne
A
Must
Department of Psychiatry, University of Ottawa, Ottawa, Ontario, Canada.
Jakov
J
Shlik
Department of Psychiatry, University of Tartu, Tartu, Estonia.
Veiko
V
Vasar
Institute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia; Centre of Excellence for Translational Medicine, University of Tartu, Tartu, Estonia.
Eero
E
Vasar
D000328:Adult; D000368:Aged; D000483:Alleles; D016022:Case-Control Studies; D015816:Cell Adhesion Molecules, Neuronal / Q000235:genetics*; D004957:Estonia; D005260:Female; D058851:GPI-Linked Proteins / Q000235:genetics; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D020641:Polymorphism, Single Nucleotide; D012559:Schizophrenia / Q000235:genetics*; D012565:Schizophrenic Psychology
D015816:Cell Adhesion Molecules, Neuronal; D058851:GPI-Linked Proteins; C095362:limbic system-associated membrane protein
Case-control genetic association study; Cell adhesion molecule; SNP