Neural correlates of social decision-making in severely antisocial adolescents.
Neurobiological and behavioral findings suggest that the development of delinquent behavior is associated with atypical social-affective processing. However, to date, no study has examined neural processes associated with social interactions in severely antisocial adolescents. In this study we investigated the behavioral and neural processes underlying social interactions of juvenile delinquents and a matched control group. Participants played the mini-Ultimatum Game as a responder while in the MRI scanner. Participants rejected unfair offers significantly less when the other player had 'no alternative' compared with a 'fair' alternative, suggesting that they took the intentions of the other player into account. However, this effect was reduced in the juvenile delinquents. The neuroimaging results revealed that juvenile delinquents showed less activation in the temporal parietal junction (TPJ) and inferior frontal gyrus (IFG). However, the groups showed similar activation levels in the dorsal anterior cingulate cortex (dACC) and the right anterior insula (AI) when norms were violated. These results indicate that juvenile delinquents with severe antisocial behavior process norm violations adequately, but may have difficulties with attending spontaneously to relevant features of the social context during interactions.
Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. vandenbos@mpib-berlin.mpg.de.
Wouter
W
van den Bos
Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS.
Pauline
P
Vahl
Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS.
Berna
B
Güroğlu
Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS.
Félice
F
van Nunspeet
Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS.
Olivier
O
Colins
Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS.
Monica
M
Markus
Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS.
Serge A R B
SA
Rombouts
Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS.
Nic
N
van der Wee
Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS.
Robert
R
Vermeiren
Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS. Leiden Institute for Brain and Cognition, Leiden, the Netherlands 2300 RC, Center for Adaptive Rationality (ARC), Max-Planck-Institute for Human Development, Berlin, Germany 14195, Leiden University, Department of Psychology, Leiden, the Netherlands, 2333 AK, Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands 2300 RC, and Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands 1018 WS.
Eveline A
EA
Crone
D000293:Adolescent; D000987:Antisocial Personality Disorder / Q000150:complications / Q000473:pathology / Q000523:psychology; D001921:Brain / Q000098:blood supply / Q000473:pathology; D001931:Brain Mapping; D003072:Cognition Disorders / Q000209:etiology*; D003657:Decision Making / Q000502:physiology*; D005260:Female; D005717:Games, Experimental; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation; D012919:Social Behavior; D013223:Statistics as Topic; D055815:Young Adult
D010100:Oxygen
IFG; TPJ; delinquents; fMRI; fairness; ultimatum game