Effect of preoperative consumption of high carbohydrate drink (Pre-Op) on postoperative metabolic stress reaction in patients undergoing radical prostatectomy.
OBJECTIVE
To investigate the effects of oral carbohydrate solution consumed until 2 h before the surgery in the patients that would undergo open radical retropubic prostatectomy on postoperative metabolic stress, patient anxiety, and comfort.


METHODS
A total of 50 adult patients, who were in ASA I-II group and would undergo open radical retropubic prostatectomy, were included in the study. While Group 1 = CH (n = 25) received oral glucose solution, Group 2 = FAM (n = 25) was famished starting from 24:00 h. Blood glucose, insulin, and procalcitonin levels of the patients were recorded, and the patients completed state-trait anxiety inventory (STAI) test, which reflects the anxiety level of the patients, both before surgery and on the postoperative 24th hour. In order to evaluate patient comfort, senses of hunger, thirst, nausea, and cold were assessed in the morning prior to the surgery.


RESULTS
No difference was observed between the two groups in terms of demographic data and insulin resistance levels (p > 0.05). Comparing with the preoperative levels, insulin resistance showed statistically significant elevation in both groups (p < 0.05). Procalcitonin levels were similarly increased in both groups in the postoperative period (p < 0.05). Preoperative and postoperative STAI state scores were similar in both groups (p > 0.05). With regard to preoperative patient comfort, sense of hunger was present in lesser number of subjects and at lower level in Group 1 (p < 0.05).


CONCLUSIONS
Preoperative consumption of high carbohydrate drink (Pre-op) decreases insulin resistance and enhances patient comfort leading to lesser sense of hunger and thirst in the preoperative period in open radical retropubic prostatectomies.
Department of Anesthesiology, Faculty of Medicine, Hacettepe University, Sıhhıye, 06100, Ankara, Turkey, ozgurcanbay@yahoo.com.
Özgür
Ö
Canbay
Serdar
S
Adar
Ayşe Heves
AH
Karagöz
Nalan
N
Çelebi
Cenk Yücel
CY
Bilen
D000328:Adult; D001007:Anxiety / Q000453:epidemiology*; D002116:Calcitonin / Q000097:blood; D015740:Calcitonin Gene-Related Peptide; D002241:Carbohydrates / Q000008:administration & dosage*; D017558:Elective Surgical Procedures; D006801:Humans; D006815:Hunger / Q000502:physiology; D007262:Infusions, Intravenous; D007333:Insulin Resistance / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011468:Prostatectomy; D011498:Protein Precursors / Q000097:blood; D013312:Stress, Physiological / Q000502:physiology*; D013894:Thirst / Q000502:physiology
C000606589:CALCA protein, human; D002241:Carbohydrates; D011498:Protein Precursors; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide