Progressive perceptual-motor impairment without generalized dementia: a type of cortical degenerative syndrome.
A patient developed slowly progressive clumsiness of both upper extremities with associated impainnent of daily activities without loss of muscle strength or abnormal muscle tone. Her sensory function was normal in the primary modalities but was impaired in the discriminative tasks. A single photon emission computed tomography using 123I-iodoamphetamine showed the areas with reduced uptake in the postcentral cortices. Based on the analysis of her motor impairment, we conclude that clumsiness of hands results from higher sensory disturbance.
Department of Neurology, Osaka University Medical School, 2-2 Yamadaoka, Suita City, Osaka 565, Japan.
K
K
Abe
Department of Neurology, Osaka University Medical School, 2-2 Yamadaoka, Suita City, Osaka 565, Japan.
S
S
Yorifuji
Department of Psychiatry, Osaka University Medical School, 2-2 Yamadaoka, Suita City, Osaka 565, Japan.
H
H
Tanabe
Department of Neurology, Osaka University Medical School, 2-2 Yamadaoka, Suita City, Osaka 565, Japan.
T
T
Yanagihara
Active touch; Exploratory movement; Motor clumsiness; Somatosensory cortex