[Horizontal transfer of antibiotic resistance genes in the environment].
The transfer of antibiotic resistance genes (ARGs), a new type of environmental pollutants, could have more adverse effects on the environment than the ARGs themselves, while the horizontal gene transfer (HGT) could be the most important propagation pathways of the ARGs, being one of the reasons for the growing pollution of ARGs in the environment. This paper systematically elaborated the molecular elements of the horizontal transfer of ARGs and the related affecting factors, which was of significance for investigating the molecular mechanisms of the horizontal transfer of the ARGs. In combining with the phylogenetic mechanisms of multiple antibiotic resistances, this paper also provided effective strategies to reduce the transfer and proliferation of ARGs in the environment. Based on the present contamination situations, the further researches on the horizontal transfer of ARGs in the environment were prospected.
College of Life Science and Biopharmaceutical, Shenyang Pharmaceutical University, Shenyang 110016, China. yangfengxiacomeon@163.com
Feng-Xia
FX
Yang
College of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China.
Da-Qing
DQ
Mao
Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria, College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China.
Yi
Y
Luo
College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China.
Qing
Q
Wang
College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China.
Quan-Hua
QH
Mu
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D004785:Environmental Pollutants / Q000032:analysis*; D022761:Gene Transfer, Horizontal; D005798:Genes, Bacterial / Q000235:genetics*
D000900:Anti-Bacterial Agents; D004785:Environmental Pollutants