[Ectopic calcification].
Calcium deposition can be observed in many tissues in addition to bones and teeth which physiologically calcify. This unphysiological calcification can damage several organs. It has been shown that vascular calcification which is a risk factor for cardiovascular events develops through similar mechanisms to physiological calcification. Further studies to clarify detailed mechanisms of calcification are necessary to develop measures that inhibit unphysiological ectopic calcification without affecting physiological calcification in bones and teeth.
Division of Nephrology & Endocrinology, Department of Medicine, University of Tokyo Hospital, Japan.
Seiji
S
Fukumoto
D000818:Animals; D015519:Bone Density; D001842:Bone and Bones / Q000378:metabolism*; D002113:Calcification, Physiologic / Q000502:physiology*; D002118:Calcium / Q000378:metabolism*; D006801:Humans; D009131:Muscle, Smooth, Vascular / Q000378:metabolism; D014652:Vascular Diseases / Q000209:etiology*
D002118:Calcium