Massive anterior chamber involvement after intra-arterial chemotherapy for retinoblastoma: ultrasound biomicroscopy and histopathology.
This case report highlights the usefulness of Ultrasound Biomicroscopy (UBM) in a case of retinoblastoma which showed massive anterior chamber involvement after treatment with intra-arterial chemotherapy. UBM was used to document tumour pseudohypopion, cells in the aqueous humor, implanted clusters of cells on the corneal endothelium, iris nodules, lens capsule deposits and ciliary body invasion. The UBM data, compared with the histopathologic analysis, performed on eye tissue, after enucleation of the affected eye, revealed a significant concordance. UBM may represent an important diagnostic tool in retinoblastoma, when the decision about enucleation of the eye must be made in the absence of histopathologic data.
Retinoblastoma Referral Center, University of Siena, Siena, Italy.
Sonia
S
De Francesco
Francesco
F
Pichi
Andrea
A
Lembo
Domenico
D
Mastrangelo
Anna
A
Paradiso
Mariacarla
M
De Luca
Paolo
P
Toti
Paolo
P
Nucci
Theodora
T
Hadjistilianou
D000867:Anterior Chamber / Q000000981:diagnostic imaging* / Q000473:pathology; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D007269:Injections, Intra-Arterial; D008297:Male; D033401:Microscopy, Acoustic; D009361:Neoplasm Invasiveness / Q000000981:diagnostic imaging; D019572:Retinal Neoplasms / Q000000981:diagnostic imaging*; D012175:Retinoblastoma / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology
D000970:Antineoplastic Agents