Hematospermia and xanthogranulomatous prostatitis: An unusual onset of a rare diagnosis.
Xanthogranulomatous prostatitis is a rare type of granulomatous prostatitis, with very few cases described. We report the clinical, radiological and pathological findings of 5 cases of xanthogranulomatous prostatitis. All patients came for recurrent episodes of hematospermia (associated with fever in 3 patients). All patients suffered from lower urinary tract symptoms and an increased prostate-specific antigen (PSA) level associated with a suspicious digital rectal examination (DRE); however, at biopsy, the results were negative for xanthogranulomatous prostatitis. Due to persistent severe bladder outlet obstruction, after unsuccessful medical treatments, all patients underwent transurethral resection of prostate (TURP). Final histological examination revealed a xanthogranulomatous prostatitis. The xanthogranulomatous prostatitis can be an incidental finding after TURP and it can simulate prostatic malignancy with PSA elevation.
Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy;
Antonio Luigi
AL
Pastore
Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy;
Giovanni
G
Palleschi
Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy;
Andrea
A
Fuschi
Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy.
Natale
N
Porta
Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy.
Bruna
B
Cerbelli
Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy.
Claudio
C
Di Cristofano
Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy.
Vincenzo
V
Petrozza
Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy;
Antonio
A
Carbone