Pharmacological intervention of nicotine dependence.
Nicotine dependence is a major cause of mortality and morbidity all over the world. Various medications have been tried to treat nicotine dependence including nicotine replacement therapy, bupropion, and varenicline. A newer venture to nicotine dependence treatment is a nicotine vaccine which is yet to get footsteps in common practice. The present review assimilates various pharmacotherapeutic measures to address nicotine dependence. However, it is to be noted that psychological interventions, when combined with pharmacotherapy, offer the greatest benefits to the patients.
National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
Raka
R
Jain
Department of Psychiatry, National Drug Dependence Treatment Center, All India Institute of Medical Sciences, New Delhi 110029, India.
Pradipta
P
Majumder
Department of Psychiatry, National Drug Dependence Treatment Center, All India Institute of Medical Sciences, New Delhi 110029, India.
Tina
T
Gupta
D001552:Benzazepines / Q000008:administration & dosage; D016642:Bupropion / Q000008:administration & dosage; D006801:Humans; D009538:Nicotine / Q000378:metabolism* / Q000633:toxicity; D011810:Quinoxalines / Q000008:administration & dosage; D061485:Tobacco Use Cessation Devices; D014029:Tobacco Use Disorder / Q000188:drug therapy* / Q000473:pathology; D000068580:Varenicline
D001552:Benzazepines; D011810:Quinoxalines; D016642:Bupropion; D009538:Nicotine; D000068580:Varenicline