Transient Fanconi syndrome in Quarter horses.
Two Quarter horses with weight loss had glucosuria, euglycemia, and a mild metabolic acidosis suggesting a proximal renal tubular defect. Further testing revealed transient generalized aminoaciduria, lactic aciduria, and glucosuria, indicating Fanconi syndrome. Both horses recovered with supportive therapy. This is the first report of acquired Fanconi syndrome in horses.
Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, 1800 Denison Avenue, Manhattan, Kansas 66502, USA (Ohmes, Davis, Beard); Department of Clinical Sciences, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Champaign, Illinois 61802, USA (Vander Werf); Department of Clinical Sciences, College of Veterinary Medicine, Purdue University, Lynn Hall, 625 Harrison Street, West Lafayette, Indiana 47907, USA (Bianco); Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, Pennsylvania 19104, USA (Giger).
Cameon M
CM
Ohmes
Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, 1800 Denison Avenue, Manhattan, Kansas 66502, USA (Ohmes, Davis, Beard); Department of Clinical Sciences, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Champaign, Illinois 61802, USA (Vander Werf); Department of Clinical Sciences, College of Veterinary Medicine, Purdue University, Lynn Hall, 625 Harrison Street, West Lafayette, Indiana 47907, USA (Bianco); Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, Pennsylvania 19104, USA (Giger).
Elizabeth G
EG
Davis
Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, 1800 Denison Avenue, Manhattan, Kansas 66502, USA (Ohmes, Davis, Beard); Department of Clinical Sciences, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Champaign, Illinois 61802, USA (Vander Werf); Department of Clinical Sciences, College of Veterinary Medicine, Purdue University, Lynn Hall, 625 Harrison Street, West Lafayette, Indiana 47907, USA (Bianco); Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, Pennsylvania 19104, USA (Giger).
Laurie A
LA
Beard
Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, 1800 Denison Avenue, Manhattan, Kansas 66502, USA (Ohmes, Davis, Beard); Department of Clinical Sciences, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Champaign, Illinois 61802, USA (Vander Werf); Department of Clinical Sciences, College of Veterinary Medicine, Purdue University, Lynn Hall, 625 Harrison Street, West Lafayette, Indiana 47907, USA (Bianco); Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, Pennsylvania 19104, USA (Giger).
Karie A
KA
Vander Werf
Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, 1800 Denison Avenue, Manhattan, Kansas 66502, USA (Ohmes, Davis, Beard); Department of Clinical Sciences, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Champaign, Illinois 61802, USA (Vander Werf); Department of Clinical Sciences, College of Veterinary Medicine, Purdue University, Lynn Hall, 625 Harrison Street, West Lafayette, Indiana 47907, USA (Bianco); Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, Pennsylvania 19104, USA (Giger).
Alex W
AW
Bianco
Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, 1800 Denison Avenue, Manhattan, Kansas 66502, USA (Ohmes, Davis, Beard); Department of Clinical Sciences, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Champaign, Illinois 61802, USA (Vander Werf); Department of Clinical Sciences, College of Veterinary Medicine, Purdue University, Lynn Hall, 625 Harrison Street, West Lafayette, Indiana 47907, USA (Bianco); Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, Pennsylvania 19104, USA (Giger).
Urs
U
Giger
D000818:Animals; D005198:Fanconi Syndrome / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000175:diagnosis* / Q000473:pathology; D006736:Horses; D008297:Male; D013997:Time Factors