Primary large cell neuroendocrine carcinoma of the renal pelvis: a case report.
We report a case of primary large cell neuroendocrine carcinoma of the renal pelvis, diagnosed in a 79-year-old man. The abdominal computed tomography showed a solid, vegetant lesion in the left renal pelvis, conditioning marked hydronephrosis. The patient underwent radical nephroureterectomy. The histological examination showed a large cell neuroendocrine carcinoma associated with a high-grade urothelial carcinoma, with local invasion (pT3). Large cell renal neuroendocrine carcinomas are rare tumors with an aggressive course and a bad prognosis. At present, only five cases were reported in literature.
Department of Urology, University of Milan, IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan - Italy.
Carlotta
C
Palumbo
Michele
M
Talso
Paolo Guido
PG
Dell'Orto
Gabriele
G
Cozzi
Elisa
E
De Lorenzis
Andrea
A
Conti
Marco
M
Maggioni
Bernardo Maria
BM
Cesare Rocco
Augusto
A
Maggioni
Francesco
F
Rocco
D000368:Aged; D018287:Carcinoma, Large Cell / Q000473:pathology / Q000601:surgery; D018278:Carcinoma, Neuroendocrine / Q000473:pathology / Q000601:surgery; D006801:Humans; D007682:Kidney Pelvis / Q000601:surgery*; D008297:Male; D060787:Neoplasm Grading; D009392:Nephrectomy / Q000379:methods; D011379:Prognosis; D016896:Treatment Outcome; D014571:Urologic Neoplasms / Q000473:pathology / Q000601:surgery