[Application of endometrial sampling device during the follow-up visit for the conservative treatment of endometrial cancer].
OBJECTIVE
To study the feasibility of endometrial sampling device as a sampling tool during the follow-up visit for endometrial cancer patients undergone conservative treatment.


METHODS
Before the hysteroscopy examination, endometrial sampling device was used to take the endometrium specimens 43 times in 19 patients who had been diagnosed as endometrial cancer or atypical hyperplasia, and were undergone conservative treatment during May 2012 to Mar. 2013. All cases accepted vaginal ultrasound screening before every sampling by endometrial sampling device. The histological results were compared with those done by hysteroscopy.


RESULTS
The average age of those patients was (30 ± 6) years old. The mean thickness of the endometrium during the treatment was (0.81 ± 0.65) cm. The qualified rate for the sampling was 95% (41/43). Compared with the specimens undergone by hysteroscopy direct sampling, 32 samples got by the endometrial sampling device with thicker endometrium (0.93 ± 0.70) cm had the same histological results, while the other 9 patients with thinner endometrium (0.40 ± 0.14) cm were not (P = 0.031).


CONCLUSIONS
The endometrial sampling device could be used during the follow-up visit for the conservative treatment patients with endometrial cancer or atypical hyperplasia, the vaginal ultrasound screening should be used together to figure out those with thinner endometrium.
Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.
Rong
R
Zhou
Dan-hua
DH
Shen
Chao-hua
CH
Wang
Jing
J
Geng
Jian-liu
JL
Wang
Email: weilhpku@163.com.
Li-hui
LH
Wei
D000328:Adult; D001706:Biopsy / Q000295:instrumentation* / Q000379:methods*; D004714:Endometrial Hyperplasia / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D004717:Endometrium / Q000473:pathology*; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015907:Hysteroscopy / Q000379:methods; D008875:Middle Aged; D011230:Precancerous Conditions / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D011372:Progestins / Q000627:therapeutic use; D012680:Sensitivity and Specificity; D055815:Young Adult
D011372:Progestins