Facile preparation of β-haloporphyrins as useful precursors of β-substituted porphyrins.
β-Haloporphyrins were efficiently prepared by halogenation of β-borylporphyrins with N-halosuccinimide and copper(I) halide. β-Haloporphyrins are useful precursors to synthesize a wide variety of β-substituted porphyrins through Pd-catalyzed cross-coupling reactions.
Department of Chemistry, Graduate School of Science, Kyoto University , Sakyo-ku, Kyoto 606-8502, Japan.
Keisuke
K
Fujimoto
Hideki
H
Yorimitsu
Atsuhiro
A
Osuka