A comparison of the effects of methylprednisolone and tenoxicam on pain, edema, and trismus after impacted lower third molar extraction.
BACKGROUND
The aim of the present study was to compare the effects of preemptive intravenous tenoxicam and methylprednisolone administrations on extraction of impacted third molars.


METHODS
This was a placebo-controlled, randomized, double-blind, clinical trial. A total of 60 adult patients ages 18-40 years with the complaints of impacted third molar teeth were included in the study.


RESULTS
The postoperative swelling ratios (p<0.05) and pain scores (p<0.05) were significantly better in both study groups than in the control group and there was no statistically significant difference between methylprednisolone and tenoxicam groups with regards to the edema and pain relief.


CONCLUSIONS
Preoperative administration of 80 mg methylprednisolone achieves better control of trismus than tenoxicam without any significant differences in edema and pain control in impacted third molar teeth extraction.
Department of Oral and Maxillofacial Surgery, Oral and Dental Health Center, Mersin, Turkey.
Ozgur
O
Ilhan
Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Dicle, Diyarbakır, Turkey.
Kamil Serkan
KS
Agacayak
Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Dicle, Diyarbakır, Turkey.
Belgin
B
Gulsun
Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Dicle, Diyarbakir, Turkey.
Mahmut
M
Koparal
Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Dicle, Diyarbakir, Turkey.
Nedim
N
Gunes
D061605:Administration, Intravenous; D000328:Adult; D000704:Analysis of Variance; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004487:Edema / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D008964:Molar, Third / Q000601:surgery; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D010147:Pain Measurement; D010894:Piroxicam / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011300:Preoperative Care / Q000379:methods; D014081:Tooth Extraction / Q000009:adverse effects*; D014313:Trismus / Q000188:drug therapy* / Q000209:etiology; D014421:Turkey
D000893:Anti-Inflammatory Agents; D010894:Piroxicam; D008775:Methylprednisolone; C032801:tenoxicam