Antimicrobial susceptibility pattern in nosocomial infections caused by Acinetobacter species in Asir Region, Saudi Arabia.
This study aimed at evaluating the sensitivity of antibiotics towards nosocomial infections caused by Acinetobacter species. The study took place during the period Dec. 2011- Dec. 2012 at Assir Central Hospital in collaboration with the department of microbiology, college of medicine, King Khalid University, Abha. A prospective study involving 150 patients presented with nosocomial infections due to Acinetobacter species detected by bacteriological tests; direct microscopy, culture in blood agar media, fermentation test in MacConkey media and MIC (minimum inhibitory concentration) for antibiotics sensitivity using Muller Hinton media and Chemical test using API 20. A 150 nosocomial infections in this study showed gram-negative coccobacilli, non motile, glucose-negative fermentor and oxidase negative. All isolates showed 100% sensitivity to: Imipramine, Meropenem, Colistin. From the rest of tested antibiotics the higher resistant ones were; Nitrofurantoin 87% and Cefoxitin 85%. The least resistant antibiotics; Imipenem 3% and Ticarcillin 7%. While variable resistance in the rest of tested antimicrobials. A 47 patients (31.3%) have used antibiotics prior to this study. The high rate of usage occurred in elder patients. The frequency of Acinetobacter calcoaceticus baumannii complex multi-drugs resistance ABCMDR is rising including almost all commonly used antibiotics. Only few antibiotics exert 100% sensitivity towards these bacteria.
Department of Microbiology, College of Medicine, King Khalid University, Abha, Saudi Arabia, 61421 Abha, P.O. 641, Saudi Arabia.
Nazar M
NM
Abdalla
Department of Family and Community Medicine, College of Medicine, King Khalid University, 61421 Abha, P.O. 641, Saudi Arabia.
Amani A
AA
Osman
Assir Central Hospital Laboratory, Abha, P.O. Box 1119, Kingdom of Saudi Arabia.
Waleed O
WO
Haimour
Department of Biology, College of Science, King Khalid University, 61413 Abha, P.O. Box 9004, Saudi Arabia.
Mohammed A A
MA
Sarhan
Bashair Hospital, Ministry of Health, Khartoum, Sudan, P.O. Box 303, Khartoum, Sudan.
Mohammed N
MN
Mohammed
Department of Microbiology, College of Medicine, King Khalid University, Abha, Saudi Arabia, 61421 Abha, P.O. 641, Saudi Arabia.
Eyhab M
EM
Zyad
Department of Microbiology, College of Medicine, King Khalid University, Abha, Saudi Arabia, 61421 Abha, P.O. 641, Saudi Arabia.
Abdalla M
AM
Al-Ghtani
D000150:Acinetobacter / Q000145:classification / Q000187:drug effects*; D000151:Acinetobacter Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003428:Cross Infection / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D011446:Prospective Studies; D012529:Saudi Arabia / Q000453:epidemiology; D013997:Time Factors
D000900:Anti-Bacterial Agents