Inhibitors of suppressive histone modification promote direct reprogramming of fibroblasts to cardiomyocyte-like cells.
Stem Cell Institute, Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA.
Hiroyuki
H
Hirai
Nobuaki
N
Kikyo
D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects / Q000502:physiology; D005347:Fibroblasts / Q000187:drug effects* / Q000378:metabolism; D006657:Histones / Q000187:drug effects* / Q000378:metabolism; D007211:Indoles / Q000494:pharmacology*; D051379:Mice; D032383:Myocytes, Cardiac / Q000166:cytology* / Q000187:drug effects* / Q000378:metabolism; D011728:Pyridones / Q000494:pharmacology*
C577920:GSK-2816126; D006657:Histones; D007211:Indoles; D011728:Pyridones