Renal capsule transplantations to assay skeletal angiogenesis.
Renal capsule transplantation is a very helpful method to grow embryonic tissues or tumors in a vascular environment, allowing long-term engraftment and biological analyses. This chapter describes the surgical procedure for the transplantation of embryonic skeletal elements in the renal capsule of adult mice and points out the manipulations that can be applied for assaying the role of angiogenesis during bone development.
Université Paris Descartes, Paris, France.
Rana
R
Abou-Khalil
Université Paris Descartes, Paris, France.
Céline
C
Colnot
D000818:Animals; D001846:Bone Development / Q000502:physiology; D001842:Bone and Bones / Q000098:blood supply*; D050476:Bowman Capsule / Q000637:transplantation*; D005260:Female; D005269:Femur / Q000098:blood supply / Q000196:embryology; D051379:Mice; D018919:Neovascularization, Physiologic / Q000502:physiology*; D011247:Pregnancy