Enzymatic polymerization of high molecular weight DNA amphiphiles that self-assemble into star-like micelles.
High molecular weight ssDNA amphiphiles are synthesized by enzymatic polymerization. These highly asymmetric diblock DNA copolymers self-assemble into "hairy", star-like micelles, shown in the AFM image and the DPD snapshot.
Dept. of Mechanical Engineering and Materials Science, Duke University, 144 Hudson Hall Box 90300, Durham, North Carolina, 27708, USA.
Lei
L
Tang
Vinalia
V
Tjong
Nan
N
Li
Yaroslava G
YG
Yingling
Ashutosh
A
Chilkoti
Stefan
S
Zauscher
D055162:Biocatalysis; D001896:Boron Compounds / Q000737:chemistry; D004277:DNA, Single-Stranded / Q000737:chemistry* / Q000378:metabolism; D004798:Enzymes / Q000378:metabolism*; D005090:Exodeoxyribonucleases / Q000378:metabolism; D008823:Micelles; D018625:Microscopy, Atomic Force; D049329:Nanostructures / Q000737:chemistry; D058105:Polymerization; D011119:Polynucleotides / Q000737:chemistry*
C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D004277:DNA, Single-Stranded; D004798:Enzymes; D008823:Micelles; D011119:Polynucleotides; D005090:Exodeoxyribonucleases; C028450:exodeoxyribonuclease I
AFM; dissipative particle dynamics; polymerase; polynucleotides; self-assembly