Radiation therapy-induced phrenic neuropathy mimicking metastasis to the diaphragmatic crus on ¹⁸F-FDG PET/CT.
Benign unilateral uptake in the diaphragmatic crus is a relatively uncommon finding on (18)F-FDG PET/CT that can mimic the appearance of malignancy in patients with known cancer, as illustrated in this patient with neuroendocrine carcinoma. It is important for the PET interpreter to recognize this finding and attribute it to benign uptake based on the patient's history and symptoms at the time of the scan. Correlation with the findings of other available imaging modalities is also important to characterize focal uptake in unusual locations.
Department of Diagnostic Radiology and Molecular Imaging, Oakland University William Beaumont School of Medicine and Beaumont Health System, Royal Oak, Michigan; and.
Prashant
P
Jolepalem
Jane Y
JY
Hwang
C Y Oliver
CY
Wong
D003937:Diagnosis, Differential; D003964:Diaphragm / Q000000981:diagnostic imaging; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008875:Middle Aged; D064847:Multimodal Imaging; D009362:Neoplasm Metastasis; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D010791:Phrenic Nerve / Q000528:radiation effects*; D049268:Positron-Emission Tomography; D011832:Radiation Injuries / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D014057:Tomography, X-Ray Computed
D019788:Fluorodeoxyglucose F18
18F-FDG PET; PET/CT; abnormal variant uptake; correlative imaging; diaphragmatic crus; oncology