A case of primary HIV type 1 and cytomegalovirus coinfection presenting with widespread clinical disease.
Coinfection of HIV-1 and cytomegalovirus (CMV) may occur given the shared routes of transmission, and the clinical presentations of each process overlap. We present a case of acute HIV-1 and CMV coinfection presenting with an acute febrile illness complicated by meningitis, hepatitis, and retinopathy. This and other similar cases demonstrate the need to consider CMV coinfection in acute HIV-1 disease, particularly in situations with significant end-organ damage.
Department of Internal Medicine, Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Joseph Y
JY
Kim
Elyse J
EJ
Singer
Laura
L
Bonelli
Jeffrey D
JD
Klausner
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D001219:Aspartate Aminotransferases / Q000097:blood; D060085:Coinfection / Q000821:virology*; D003586:Cytomegalovirus Infections / Q000150:complications*; D004359:Drug Therapy, Combination; D005334:Fever / Q000821:virology; D005654:Fundus Oculi; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D015497:HIV-1; D006510:Hepatitis B Antibodies / Q000097:blood; D006801:Humans; D006987:Hypesthesia / Q000821:virology; D008297:Male; D008587:Meningitis, Viral / Q000821:virology; D010292:Paresthesia / Q000821:virology; D012164:Retinal Diseases / Q000150:complications
D044966:Anti-Retroviral Agents; D006510:Hepatitis B Antibodies; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
HIV type 1; hepatitis; human cytomegalovirus; meningitis; primary coinfection; retinitis