Type D personality is unrelated to major adverse cardiovascular events in patients with coronary artery disease treated by intracoronary stenting.
BACKGROUND
Previous research in cardiac patients suggested that type D personality, defined as a combination of negative affectivity (NA) and social inhibition (SI), was associated with adverse outcome.


OBJECTIVE
The objective of this prospective study was to examine the independent prognostic value of type D in patients with coronary artery disease (CAD).


METHODS
A total of 465 patients completed the Type D Scale (DS14) questionnaire before undergoing stent implantation and were followed up for 5 years.


RESULTS
In a Cox regression model adjusted for selected confounders, we found a trend towards NA for the prediction of nonfatal major adverse cardiovascular event (MACE, hazard ratio (HR) = 1.07, 95 % confidence intervals (CIs) = 0.99-1.14, p = 0.074), while, in contrast, SI was a significant and independent predictor of better outcome (HR = 0.92, 95 % CI = 0.86-0.99, p = 0.027).


CONCLUSIONS
In a cohort of CAD patients, the type D pattern was not linked to adverse outcome, whereas SI was negatively associated with MACE.
Department of Psychosomatic Medicine and Psychotherapy, University of Göttingen, Göttingen, Germany.
Thomas
T
Meyer
Sharif
S
Hussein
Helmut W
HW
Lange
Christoph
C
Herrmann-Lingen
D003327:Coronary Disease / Q000150:complications / Q000175:diagnosis / Q000523:psychology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects / Q000523:psychology; D010556:Personality Tests; D011379:Prognosis; D016016:Proportional Hazards Models; D011446:Prospective Studies; D015607:Stents; D016896:Treatment Outcome; D064415:Type D Personality