A cellular gene as a double surveillance agent for plant to combat pathogen.
The tomato extreme resistance R-gene encodes Tm2/ Tm22 protein that interacts with the tobamovirus movement protein (MP) to induce hypersensitive response (HR) resulting in local resistance. R-gene mediated local resistance requires a functional RbCS that interacts with MP, restricting virus local infection. RbCS-MP interaction is also required for tobamovirus systemic infection. “Loss-of-function” RbCS allows local but not systemic infection. Thus, RbCS, a cellular gene, acts as a double surveillance agent to protect plant from pathogenic attack, suggesting a previously un-recognized defense strategy in plants.
Bin
B
Li
Hu
H
Feng
Qi
Q
Zhang
Xian
X
Zhang
Yiguo
Y
Hong
D018551:Solanum lycopersicum / Q000235:genetics / Q000378:metabolism* / Q000821:virology*; D010935:Plant Diseases / Q000821:virology; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D030821:Plants, Genetically Modified / Q000235:genetics / Q000378:metabolism* / Q000821:virology; D017898:Tobamovirus / Q000378:metabolism / Q000472:pathogenicity
D010940:Plant Proteins