Pd-Catalyzed kinetic resolution of cyclic enol ethers. An enantioselective route to functionalised pyrans.
Functionalised cyclic enol ethers can be recovered with high levels of enantiocontrol after an asymmetric catalytic [1,3]-rearrangement reaction. These compounds can be further elaborated to a series of carbo- and heterocyclic products in good yield and with excellent levels of stereocontrol.
Department of Chemistry, University of Sheffield, Brook Hill, Sheffield, S3 7HF, UK. j.harrity@sheffield.ac.uk.
Jean-Olivier
JO
Zirimwabagabo
Joseph P A
JP
Harrity