[Factors linked to foveoschisis in high myopia].
OBJECTIVE
To investigate the factors linked to foveoschisis in high myopia.


METHODS
Retrospective study of 113 patients (200 eyes) with high myopia was conducted between January 2010 and June 2012. Subjects underwent a complete ophthalmic examination, spectral domain optical coherence tomography (OCT TOPCON 2000) and ocular echography.


RESULTS
Of the 200 eyes, 22 (11%) had foveoschisis on OCT examination. On the basis of univariate analysis, five variables were associated with the pathologic changes, including spherical equivalent over 10 diopters (P=0.044), axial length over 30 mm (P=0.0028), macular chorioretinal atrophy (P=0.0009), posterior staphyloma (P=0.0007) and vitreoretinal interface factors (P=0.0002). In the multivariate analysis, three factors were independently associated with foveoschisis in high myopia: axial length (adjusted OR, 16.7; IC 95% 1.4-219.7, P=0.036), macular chorioretinal atrophy (adjusted OR, 13.2; IC 95%, 1.3-133.1, P=0.044), and vitreoretinal interface factors (adjusted OR, 36.1; IC 95%, 3.5-376.9, P=0.002).


CONCLUSIONS
In our study, axial length, macular chorioretinal atrophy, and vitreoretinal interface factors were independently associated foveoschisis in highly myopic eyes.
Service d'ophtalmologie B, institut Hédi-Rais, boulevard 9-Avril, 1006 Tunis, Tunisie. Electronic address: chebilahmed@yahoo.fr.
A
A
Chebil
Service d'ophtalmologie B, institut Hédi-Rais, boulevard 9-Avril, 1006 Tunis, Tunisie.
B
B
Ben Achour
Service d'ophtalmologie B, institut Hédi-Rais, boulevard 9-Avril, 1006 Tunis, Tunisie.
N
N
Chaker
Service d'ophtalmologie B, institut Hédi-Rais, boulevard 9-Avril, 1006 Tunis, Tunisie.
M
M
Bouladi
Service d'ophtalmologie B, institut Hédi-Rais, boulevard 9-Avril, 1006 Tunis, Tunisie.
H
H
Charfi
Service d'ophtalmologie B, institut Hédi-Rais, boulevard 9-Avril, 1006 Tunis, Tunisie.
L
L
El Matri
D000328:Adult; D001284:Atrophy / Q000150:complications / Q000453:epidemiology; D019773:Epiretinal Membrane / Q000150:complications / Q000453:epidemiology; D015818:Eye Infections, Bacterial / Q000150:complications / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications* / Q000453:epidemiology; D015995:Prevalence; D012160:Retina / Q000473:pathology; D012167:Retinal Perforations / Q000150:complications / Q000453:epidemiology; D041441:Retinoschisis / Q000453:epidemiology* / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult
Atrophie choriorétinienne; Axial length; Chorioretinal atrophy; Foveoschisis; Fovéoschisis; High myopia; Longueur axiale; Myopie forte; Posterior staphyloma; Retinal; Staphylome postérieur