Use of electroacupuncture to accelerate the antidepressant action of selective serotonin reuptake inhibitors: a single-blind, randomised, controlled study.
1. Patients treated with dense cranial electroacupuncture stimulation (DCEAS) had a significantly greater reduction in the 17-item Hamilton Rating Scale for Depression scores and clinically significant response to treatment than those having sham acupuncture (19.4% vs.8.8%). 2. Neither sham acupuncture nor DCEAS had effects on the platelet serotonin system. 3. In the early phase of selective serotonin reuptake inhibitor treatment for depressed patients, DCEAS could be used as an additional therapy. 4. Neurobiological mechanisms responsible for DCEAS effects warrant further investigation using neuroimaging.
School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong.
Z J
ZJ
Zhang
R
R
Ng
S C
SC
Man
J T Y
JT
Li
W
W
Wong
H K
HK
Wong
D
D
Wang
M T
MT
Wong
A W K
AW
Tsang
K C
KC
Yip
S C W
SC
Sze
D003131:Combined Modality Therapy; D015671:Electroacupuncture; D005473:Fluoxetine / Q000627:therapeutic use*; D006801:Humans; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D016037:Single-Blind Method
D005473:Fluoxetine; D017367:Selective Serotonin Reuptake Inhibitors