Exacerbation of interstitial granulomatous dermatitis with arthritis by anakinra in a patient with diffuse large B-cell lymphoma.
Interstitial granulomatous dermatitis with arthritis (IGDA) is a rare idiopathic skin disorder with variable cutaneous expression, typically associated with a seronegative arthritis. Histopathology of this disorder reveals a granulomatous infiltrate with foci of collagen degeneration in the deep reticular dermis. We present a case of IGDA in a 56-year-old man with diffuse large B-cell lymphoma, exacerbated by the administration of anakinra.
Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Greece. de.michailidou@gmail.com.
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Michailidou
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Voulgarelis
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Pikazis
D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols; D001168:Arthritis / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D001706:Biopsy; D003872:Dermatitis / Q000209:etiology / Q000276:immunology / Q000473:pathology / Q000628:therapy; D018450:Disease Progression; D006099:Granuloma; D006801:Humans; D053590:Interleukin 1 Receptor Antagonist Protein / Q000008:administration & dosage / Q000009:adverse effects*; D008198:Lymph Nodes / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015166:Monitoring, Immunologic / Q000379:methods; D009333:Neck; D016896:Treatment Outcome; D028761:Withholding Treatment
D000970:Antineoplastic Agents; D053590:Interleukin 1 Receptor Antagonist Protein