Enucleate or replicate? Ask the cytoskeleton.
In this issue of Blood, Sui and colleagues have identified novel and interesting roles for Tropomodulin (Tmod)-3, a protein involved with actin filament organization, in erythroid proliferation, survival, and enucleation.
WEILL CORNELL MEDICAL COLLEGE.
Stefano
S
Rivella
D000818:Animals; D015672:Erythroid Precursor Cells / Q000378:metabolism*; D005260:Female; D017353:Gene Deletion; D008099:Liver / Q000196:embryology*; D008297:Male; D051348:Tropomodulin / Q000235:genetics*
C495837:Tmod3 protein, mouse; D051348:Tropomodulin