Growth, reproductive performance, carcass characteristics and meat quality in F1 and F2 progenies of somatic cell-cloned pigs.
The objective of this study was to examine the health and meat production of cloned sows and their progenies in order to demonstrate the application of somatic cell cloning to the pig industry. This study compared the growth, reproductive performance, carcass characteristics and meat quality of Landrace cloned sows, F1 progenies and F2 progenies. We measured their body weight, growth rate and feed conversion and performed a pathological analysis of their anatomy to detect abnormalities. Three of the five cloned pigs were used for a growth test. Cloned pigs grew normally and had characteristics similar to those of the control purebred Landrace pigs. Two cloned gilts were bred with a Landrace boar and used for a progeny test. F1 progenies had characteristics similar to those of the controls. Two of the F1 progeny gilts were bred with a Duroc or Large White boar and used for the progeny test. F2 progenies grew normally. There were no biological differences in growth, carcass characteristics and amino acid composition among cloned sows, F1 progenies, F2 progenies and conventional pigs. The cloned sows and F1 progenies showed normal reproductive performance. No specific abnormalities were observed by pathological analysis, with the exception of periarteritis in the F1 progenies. All pigs had a normal karyotype. These results demonstrate that cloned female pigs and their progenies have similar growth, reproductive performance and carcass quality characteristics and that somatic cell cloning could be a useful technique for conserving superior pig breeds in conventional meat production.
Ibaraki Prefecture Livestock Research Center, Ibaraki 315-0132, Japan.
Noritaka
N
Adachi
Daisuke
D
Yamaguchi
Akiyuki
A
Watanabe
Narumi
N
Miura
Seiji
S
Sunaga
Hitoshi
H
Oishi
Michiko
M
Hashimoto
Takatsugu
T
Oishi
Masaki
M
Iwamoto
Hirofumi
H
Hanada
Masanori
M
Kubo
Akira
A
Onishi
D000818:Animals; D001835:Body Weight / Q000502:physiology; D019976:Cloning, Organism / Q000662:veterinary; D005260:Female; D008297:Male; D008460:Meat; D053652:Nuclear Transfer Techniques / Q000662:veterinary; D012098:Reproduction / Q000235:genetics / Q000502:physiology*; D013552:Swine / Q000254:growth & development / Q000502:physiology*