Co-occurring Duchenne muscular dystrophy and hypertrophic cardiomyopathy in an adult with atypical cardiac phenotype.
We present the case of a 29-year-old man with mutation-positive Duchenne muscular dystrophy and mutation-positive hypertrophic cardiomyopathy. His cardiac phenotype has characteristics of both disorders; he manifests sub-epicardial left ventricular free wall late gadolinium enhancement that is consistent with Duchenne cardiomyopathy, as well as asymmetric ventricular septal hypertrophy, hyperdynamic left ventricular systolic function, and septal mid-myocardial late gadolinium enhancement, which are characteristic of hypertrophic cardiomyopathy.
1The Heart Institute,Cincinnati Children's Hospital Medical Center,Cincinnati,Ohio,United States of America.
Animesh
A
Tandon
1The Heart Institute,Cincinnati Children's Hospital Medical Center,Cincinnati,Ohio,United States of America.
Michael D
MD
Taylor
2The Heart Center,Nationwide Children's Hospital,Columbus,Ohio,United States of America.
Linda H
LH
Cripe
D000328:Adult; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D020388:Muscular Dystrophy, Duchenne / Q000150:complications / Q000175:diagnosis*; D010641:Phenotype
cardiac magnetic resonance imaging