Bradbury-Eggleston syndrome - an unusual cause of gastroesophageal reflux disease (GERD).
The report presents a case of a 46-year-old male patient, previously treated because of dysphagia, pyrosis, vertigo while standing up and impotency. Manometric and pH-metric analysis showed presence of gastroesophageal reflux disease (GERD) caused by transient relaxation of lower esophageal sphincter (TRLES). Heart-rate variability showed decreased sympathetic function. Electromyoneurography showed a neurological lesion in muscles of upper extremities. The patient received midodrine and clonazepam which resolved this condition. These findings suggest that a neurological disorder can be a cause of GERD.
1Clinical Hospital Center Bežanijska kosa, 2Clinical Center of Serbia, Belgrade; Serbia.
Igor
I
D Jovanović
Dragana
D
R Jovanović
Sanja
S
Pavlović
Branislav
B
Milovanović
Milenko
M
Uglješić
Nikola
N
Milinić
Mirjana
M
Cvetković
Marija
M
Branković
Goran
G
Nikolić
D005764:Gastroesophageal Reflux / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D054970:Pure Autonomic Failure / Q000150:complications*