Neuropathic pain in neuromyelitis optica affects activities of daily living and quality of life.
Though pain in neuromyelitis optica (NMO) has been described in two recent reports, the proportion with true neuropathic pain (NP), its features, impact on activities of daily living (ADL) and quality of life has not been well characterised. A cross-sectional study of 50 NMO patients with transverse myelitis was performed using Douleur Neuropathique 4, Brief Pain Inventory, Extended Disability Status Scale and Short Form 36. NP was identified in 62% of patients. Pain was constant in 68% affecting most ADL. Pain was associated with significant reduction of the SF36 Mental Composite Score. The high prevalence of NP and associated disability necessitates an in-depth enquiry in patients with NMO.
NMO Clinical Service, The Walton Centre, Liverpool, UK stevenzhao25@gmail.com.
Sizheng
S
Zhao
NMO Clinical Service, The Walton Centre, Liverpool, UK.
Kerry
K
Mutch
NMO Clinical Service, The Walton Centre, Liverpool, UK.
Liene
L
Elsone
NMO Clinical Service, The Walton Centre, Liverpool, UK.
Turo
T
Nurmikko
NMO Clinical Service, The Walton Centre, Liverpool, UK.
Anu
A
Jacob
D000203:Activities of Daily Living; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001323:Autoantibodies / Q000276:immunology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009188:Myelitis, Transverse / Q000150:complications; D009437:Neuralgia / Q000209:etiology / Q000276:immunology / Q000503:physiopathology*; D009471:Neuromyelitis Optica / Q000150:complications / Q000276:immunology / Q000503:physiopathology*; D011788:Quality of Life; D055815:Young Adult
D001323:Autoantibodies
Neuromyelitis optica; SF36; aquaporin 4; brief pain inventory; demyelinating; neuropathic pain; pain; quality of life