Engineered peptides for nanohybrid assemblies.
Inspired by biological material synthesis, synthetic biomineralization peptides have been screened through a laboratory evolution using biocombinatorial techniques. In this study, using the fine examples in nature, silica binding peptides and gold binding peptides were fused together to form a hybrid peptide. We designed fusion peptides with different gold binding and silica binding parts. First, we have tested the binding capability of the fusion peptides using quartz crystal microbalance on gold surface and silica surface. Second, S1G1 hybrid peptide enabled assembly of gold nanoparticles on a silica surface was achieved. Finally, nanomaterial synthesis ability of the S1G1 peptide was presented by the formation of a silica film on a gold surface. In this study, we are presenting a hybrid peptide tool for nanohybrid assembly as a promising route for nanotechnology applications.
Luminous! Center of Excellence for Semiconductor Lighting and Displays, School of Electrical and Electronic Engineering, School of Physical and Mathematical Sciences, Nanyang Technological University , Nanyang Avenue, Singapore 639798, Singapore.
Urartu Ozgur Safak
UO
Seker
Vijay Kumar
VK
Sharma
Shahab
S
Akhavan
Hilmi Volkan
HV
Demir
D006046:Gold / Q000737:chemistry*; D008567:Membranes, Artificial; D053768:Metal Nanoparticles / Q000737:chemistry*; D019151:Peptide Library; D015202:Protein Engineering / Q000379:methods; D012822:Silicon Dioxide / Q000737:chemistry*; D013499:Surface Properties
D008567:Membranes, Artificial; D019151:Peptide Library; D006046:Gold; D012822:Silicon Dioxide