Bullous pemphigoid in a 3-month-old infant: case report and literature review of this dermatosis in childhood.
Bullous pemphigoid is an autoimmune subepidermal blistering dermatosis that is uncommon in childhood. We report a case of a female infant, 3 months old, which presented clinical and laboratory data for the confirmatory diagnosis of bullous pemphigoid. The authors used immunohistochemical staining for collagen type IV that allowed the differentiation of bullous pemphigoid from other subepidermal bullous diseases. Opportunely we review the clinical, immunological, therapeutic and prognostic features of this pathology in children.
Brasilia Catholic University, MD, Board certified dermatologist - Professor of dermatology at Brasilia Catholic University (UCB). Dermatologist at the Distrito Federal Health State Secretariat (SES-DF) - Brasília (DF), Brazil.
Eugenio Galdino de Mendonça
EG
Reis-Filho
Asa Norte Regional Hospital, BrasíliaDF, Brazil, MD - Resident in Dermatology at Asa Norte Regional Hospital (HRAN) - Brasília (DF), Brazil.
Tainah de Almeida
Tde A
Silva
Asa Norte Regional Hospital, Preceptor of the Dermatology Residency Program, BrasíliaDF, Brazil, MD, Board certified dermatologist. Preceptor of the Dermatology Residency Program at Asa Norte Regional Hospital (HRAN) - Brasília (DF), Brazil.
Luiza Helena de Lima
LH
Aguirre
Brasilia Catholic University, MD, Board certified dermatologist - Professor of dermatology at Brasilia Catholic University (UCB). Dermatologist at the Distrito Federal Health State Secretariat (SES-DF) - Brasília (DF), Brazil.
Carmelia Matos Santiago
CM
Reis
D001768:Blister / Q000188:drug therapy / Q000473:pathology; D024042:Collagen Type I / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D010391:Pemphigoid, Bullous / Q000188:drug therapy / Q000473:pathology*; D012867:Skin / Q000473:pathology; D016896:Treatment Outcome
D024042:Collagen Type I