[Analysis of actual effects of combining xiyanping injection with vitamin C injection in treatment of upper respiratory tract infection].
OBJECTIVE
To investigate whether Xiyanping injection associated with vitamin C injection will improve the cure rate of upper respiratory tract infection compared to treatment with Xiyanping injection alone.


METHODS
The analysis was based on hospital information system (HIS) data. Patients were divided into two groups according to whether he or she accepted the addition of vitamin C to treatment with Xiyanping injection. We used the propensity score to balance confounding factors, and made confounding factors which cannot be balanced by the propensity score to act as covariate variables. Then Logistic regression was used to evaluate the effectiveness of the two groups.


RESULTS
There was no significant difference between the 2 groups.


CONCLUSIONS
Compared with Xiyanping injection alone, using vitamin C in combination does not improve the treatment effectiveness of upper respiratory tract infection.
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. wzhftcm@163.com
Zhi-Fei
ZF
Wang
Renmin University of China, Beijing 100872, China.
Jian
J
Huo
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Yan-Ming
YM
Xie
D000293:Adolescent; D000328:Adult; D001205:Ascorbic Acid / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006751:Hospital Information Systems / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D016896:Treatment Outcome; D055815:Young Adult
D004365:Drugs, Chinese Herbal; D001205:Ascorbic Acid