New evidence in trauma resuscitation - is 1:1:1 the answer?
Traumatic injury is a common problem, with over five million worldwide deaths from trauma per year. An estimated 10 to 20% of these deaths are potentially preventable with better control of bleeding. Damage control resuscitation involves early delivery of plasma and platelets as a primary resuscitation approach to minimize trauma-induced coagulopathy. Plasma, red blood cell and platelet ratios of 1:1:1 appear to be the best substitution for fresh whole blood; however, the current literature consists only of survivor bias-prone observational studies.
Department of Anesthesiology, Duke University Medical Center, 5677 HAFS Building, Box 3094, Durham NC 27710, UK. timothy.miller2@duke.edu.
Timothy E
TE
Miller