A simplified sequence-based identification scheme for Bordetella reveals several putative novel species.
The differentiation of Bordetella species, particularly those causing human infection, is problematic. We found that sequence analysis of an internal fragment of nrdA allowed differentiation of the currently named Bordetella species. Analysis of 107 "Bordetella" isolates recovered almost exclusively from human respiratory tract specimens identified several putative novel species.
Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Theodore
T
Spilker
Amy L
AL
Leber
Mario J
MJ
Marcon
Duane W
DW
Newton
Rebecca
R
Darrah
Peter
P
Vandamme
John J
JJ
Lipuma
D001884:Bordetella / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D001885:Bordetella Infections / Q000382:microbiology; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D012141:Respiratory Tract Infections / Q000382:microbiology; D012262:Ribonucleoside Diphosphate Reductase / Q000235:genetics; D017422:Sequence Analysis, DNA
D004269:DNA, Bacterial; D012262:Ribonucleoside Diphosphate Reductase