Fatal paraneoplastic embolisms in both circulations in a patient with poorly differentiated neuroendocrine tumour.
Arterial embolism with lower limb ischemia is a rare manifestation of paraneoplastic hypercoagulability in cancer patients. We report a unique case of fatal thromboembolism involving both circulations associated with a poorly differentiated neuroendocrine tumor of the lung with rapid progress despite high doses of unfractioned heparin and review the current literature on anticoagulative regimen in tumour patients.
Department of General, Visceral, Vascular and Paediatric Surgery, Julius Maximilians University of Wuerzburg, Oberduerrbacher Street 6, 97080 Wuerzburg, Germany.
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Busch
Institute of Pathology, Julius Maximilians University of Wuerzburg, Oberduerrbacher Street 6, 97080 Wuerzburg, Germany.
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Tschernitz
Institute of Radiology, Julius Maximilians University of Wuerzburg, Oberduerrbacher Street 6, 97080 Wuerzburg, Germany.
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Thurner
Department of General, Visceral, Vascular and Paediatric Surgery, Julius Maximilians University of Wuerzburg, Oberduerrbacher Street 6, 97080 Wuerzburg, Germany.
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Kellersmann
Department of General, Visceral, Vascular and Paediatric Surgery, Julius Maximilians University of Wuerzburg, Oberduerrbacher Street 6, 97080 Wuerzburg, Germany.
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Lorenz