[Clinical outcomes research on parenterally administered kudiezi in treatment of cerebral infarction].
OBJECTIVE
To investigate the curative effect of Kudiezi Injection in the treatment of cerebral infarction.


METHODS
Hospital information system (HIS) data from 18 national, general hospitals were used to compare patients with and without the use of parenterally administered Kudiezi injection in treating cerebral infarction. To balance confounding factors between the two groups propensity score method was used; effectiveness evaluation of parenterally administered Kudiezi in treatment of cerebral infarction was carried out using Logistic regression method.


RESULTS
There was a statistically significant difference (P < 0.05) between positive curative outcomes in those receiving conventional therapy plus Kudiezi injection compared to those using other parenterally received medications on cerebral infarction.


CONCLUSIONS
According to the current data conventional therapy combined with parenterally administered Kudiezi has a better outcome to cure cerebral infarction than other parenterally administered medications. This data provides a reference for clinical medication. However, the exact conclusions still need further verification.
Institute of Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. cyp2668@163.com
Yan-Peng
YP
Chang
Renmin University of China, Beijing 100872, China.
Lin
L
Li
Institute of Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Yan-Ming
YM
Xie
The PLA Navy General Hospital, Beijing 100048, China.
Yan
Y
Zhuang
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002544:Cerebral Infarction / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006751:Hospital Information Systems / Q000706:statistics & numerical data; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D064792:Pragmatic Clinical Trials as Topic; D055815:Young Adult
D004365:Drugs, Chinese Herbal