Differential contributions of the superior and inferior parietal cortex to feedback versus feedforward control of tools.
Damage to the superior and/or inferior parietal lobules (SPL, IPL) (Sirigu et al., 1996) or cerebellum (Grealy and Lee, 2011) can selectively disrupt motor imagery, motivating the hypothesis that these regions participate in predictive (i.e., feedforward) control. If so, then the SPL, IPL, and cerebellum should show greater activity as the demands on feedforward control increase from visually-guided execution (closed-loop) to execution without visual feedback (open-loop) to motor imagery. Using fMRI and a Fitts' reciprocal aiming task with tools directed at targets in far space, we found that the SPL and cerebellum exhibited greater activity during closed-loop control. Conversely, open-loop and imagery conditions were associated with increased activity within the IPL and prefrontal areas. These results are consistent with a superior-to-inferior gradient in the representation of feedback-to-feedforward control within the posterior parietal cortex. Additionally, the anterior SPL displayed greater activity when aiming movements were performed with a stick vs. laser pointer. This may suggest that it is involved in the remapping of far into near (reachable) space (Maravita and Iriki, 2004), or in distalization of the end-effector from hand to stick (Arbib et al., 2009).
School of Psychological Science, Oregon State University, Corvallis, OR 97331, USA. Electronic address: Kristen.Macuga@oregonstate.edu.
Kristen L
KL
Macuga
Department of Psychological Sciences & Brain Imaging Center, University of Missouri, Columbia, MO 65211, USA. Electronic address: freys@missouri.edu.
Scott H
SH
Frey
D000328:Adult; D001931:Brain Mapping; D025461:Feedback, Physiological / Q000502:physiology*; D005260:Female; D006225:Hand / Q000502:physiology*; D006801:Humans; D007092:Imagination / Q000502:physiology*; D008297:Male; D009068:Movement / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology*; D010296:Parietal Lobe / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*; D055815:Young Adult
Cerebellum; Motor imagery; Posterior parietal cortex; Sensorimotor control; Tool use; Visually guided movement