Borderline ovarian tumors, fertility-sparing surgery and pregnancy outcome.
BACKGROUND
Borderline ovarian tumors (BOTs) represent a type of epithelial tumors having a biologic intermediate behavior between clearly malignant and straight benign tumors. Most of BOTs interest women during fertile age, for which it is necessary to consider a fertility sparing surgery.


OBJECTIVE
To evaluate the clinical aspects and pregnancy rate of women affected by borderline ovarian tumors who have undergone fertility sparing surgery.


METHODS
A study of 22 patients affected by BOTs who have been treated with a fertility sparing surgery was conducted between January 2005 and October 2011 at Sant'Andrea Hospital, "Sapienza" University of Rome. The patients' characteristics analyzed were: age, histological type, tumor size, adnexal surgery, pre-operative serum CA-125, diagnostic circumstances, number of patients who became pregnant and number of overall pregnancies.


RESULTS
Among the 22 patients treated with a fertility sparing surgery, only sixteen wanted to get pregnant. Eleven patents out of 16 accomplished it. The pregnancy rate was 68.7%.


CONCLUSIONS
Fertility sparing surgery can be considered a safe procedure for young women affected by borderline ovarian tumors.
Department of Gynecological, Obstetric and Urological Sciences, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy. angelicacatalano87@hotmail.it.
A
A
Frega
A C
AC
Coluccia
G
G
Di Martino
A
A
Catalano
G N
GN
Milazzo
C
C
Assorgi
F
F
Manzara
G D
GD
Romeo
M
M
Gentile
R
R
Marziani
M
M
Moscarini
D000328:Adult; D018394:CA-125 Antigen / Q000378:metabolism; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D010051:Ovarian Neoplasms / Q000503:physiopathology* / Q000601:surgery*; D010052:Ovariectomy / Q000379:methods; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate
D018394:CA-125 Antigen