Comprehensive metagenomic approach for detecting causative microorganisms in culture-negative infective endocarditis.
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Atsuko
A
Imai
Department of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Kazuyoshi
K
Gotoh
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. Electronic address: asano@cardiology.med.osaka-u.ac.jp.
Yoshihiro
Y
Asano
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Noriaki
N
Yamada
Department of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Daisuke
D
Motooka
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Masaki
M
Fukushima
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Machiko
M
Kanzaki
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Tomohito
T
Ohtani
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Yasushi
Y
Sakata
Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Hiroyuki
H
Nishi
Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Koichi
K
Toda
Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Yoshiki
Y
Sawa
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Issei
I
Komuro
Department of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Toshihiro
T
Horii
Department of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Tetsuya
T
Iida
Department of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Shota
S
Nakamura
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan; Department of Medical Biochemistry, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Seiji
S
Takashima
D000368:Aged; D004696:Endocarditis / Q000175:diagnosis / Q000235:genetics; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000235:genetics*; D013293:Enterococcus faecalis / Q000235:genetics* / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008297:Male; D056186:Metagenomics / Q000379:methods*; D008875:Middle Aged; D013295:Streptococcus mutans / Q000235:genetics* / Q000302:isolation & purification
Culture-negative infective endocarditis; Metagenomic analysis; Next generation sequencing