[Analysis of salvianolate injection combined with usual drugs in treatment of coronary heart disease in real world].
OBJECTIVE
Based on real world research the circumstances of the clinical use of usual drugs combined with salvianolate injection are surveyed.


METHODS
Descriptive statistics on the use of salvianolate injection in 18 general hospitals in China.


RESULTS
In 1 605 patients with coronary heart disease (CHD), salvianolate injection was most frequently (51%) combined with clopidogrel and isosorbide dinitrate. In addition this combination showed a higher clinical effectiveness as compared with other drug combinations.


CONCLUSIONS
In the real world, salvianolate injection combined with usual treatment was found to be more effective than other treatment combinations. In addition practice conformed to the clinical treatment of coronary heart disease (CHD) guidelines for drug use. However, liver and kidney function, routine blood tests and the blood's coagulation function require ongoing monitoring.
Institute of Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. cyp2668@163.com
Yan-Peng
YP
Chang
Renmin University of China, Beijing 100872, China.
Hui
H
Zhang
Institute of Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Yan-Ming
YM
Xie
Renmin University of China, Beijing 100872, China.
Xian-Bin
XB
Zeng
Renmin University of China, Beijing 100872, China.
Jian
J
Hu
The PLA Navy General Hospital, Beijing 100048, China.
Yan
Y
Zhuang
D000368:Aged; D000369:Aged, 80 and over; D000077144:Clopidogrel; D003327:Coronary Disease / Q000188:drug therapy* / Q000401:mortality; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006751:Hospital Information Systems / Q000706:statistics & numerical data; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000008:administration & dosage*; D064792:Pragmatic Clinical Trials as Topic; D057216:Propensity Score; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016896:Treatment Outcome
D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; C561960:salvianolate; D000077144:Clopidogrel; D007548:Isosorbide Dinitrate; D013988:Ticlopidine