Comprehensive visualization of paresthesia in breast cancer survivors.
OBJECTIVE
As breast cancer survivors are benefiting increasingly from advanced forms of therapy, the side effects of locoregional treatment in the adjuvant setting are becoming more and more important. This article presents a new method of assessing the spatial distribution of paresthesia in breast cancer survivors after different locoregional treatments.


METHODS
A structured questionnaire assessing paresthesia, with body pictograms for marking paresthesia areas, was completed by 343 breast cancer survivors. The image information was digitized, generating gray-scale summation images with numbers from 0, indicating black (100 % of the patients had paresthesia), to 255, indicating white (none had paresthesia). The resulting map visualization showed the locations of paresthesia on body pictograms. The group included patients who had undergone breast-conserving surgery (BCS) and mastectomy, and also patients who had received percutaneous and interstitial radiation.


RESULTS
A total of 56.5 % of the patients stated that they had paresthesia. The paresthesia areas were distributed within the range suggested by clinical experience. Most patients stated that they had paresthesia in the upper outer quadrant and axilla. Patients who had undergone mastectomy or percutaneous radiotherapy appeared to have more paresthesia on some areas of the body surface. Patients who had undergone mastectomy indicated larger areas of paresthesia than those with BCS-4,066 pixels (px) vs. 2,275 px. Radiotherapy did not appear to influence the spatial distribution of paresthesia.


CONCLUSIONS
Paresthesia is a common symptom after breast cancer treatment. This paper describes a new method of assessing this side effect to improve and individualize treatment for it in the future.
Department of Gynecology and Obstetrics, University Breast Center for Franconia, Erlangen University Hospital, Universitaetsstrasse 21-23, 91054, Erlangen, Germany, sebastian.jud@uk-erlangen.de.
Sebastian M
SM
Jud
Reinhard
R
Hatko
Christian
C
Maihöfner
Mayada R
MR
Bani
Michael G
MG
Schrauder
Michael P
MP
Lux
Matthias W
MW
Beckmann
Gassan
G
Bani
Irina
I
Eder
Peter A
PA
Fasching
Christian R
CR
Loehberg
Claudia
C
Rauh
Alexander
A
Hein
D000328:Adult; D000368:Aged; D001365:Axilla; D001943:Breast Neoplasms / Q000601:surgery*; D003430:Cross-Sectional Studies; D005260:Female; D005858:Germany; D006801:Humans; D008408:Mastectomy / Q000009:adverse effects*; D008875:Middle Aged; D010292:Paresthesia; D010465:Perception; D011184:Postoperative Period; D012189:Retrospective Studies; D012984:Software; D011795:Surveys and Questionnaires; D017741:Survivors / Q000706:statistics & numerical data