Efficacy of Eremostachys laciniata herbal extract on mitigation of pain after hysterectomy surgery.
Pain is the most common complaint in all kinds of diseases. Considering side effects of chemical medicines as well as unnecessary continuation of pain after surgery, the present study aimed at evaluating anti-pain effect of Chelledaghi herbal extract on mitigation of pain after hysterectomy surgery. This study was conducted on 90 randomly selected patients. The subjects were divided into three groups each of them consisting of 30 cases. One group was regarded as control and two other groups as case groups. The group A (control group) received the placebo from 24 h before surgery to 24 h after surgery. The group B (case I) received placebo 24 h before surgery and medicine containing Chelledaghi herbal extract for 24 h after surgery. The group C (case II) received medicine containing Chelledaghi herbal extract which was prepared as a suppository from 24 before to 24 h after surgery for every 12 h. Then, pain severity based on VAS within different time intervals after surgery. Mitigation rate of pain after surgery, need to use sedatives, low dosage of the consumed anti-pain medicine and pain severity after surgery were all better in the groups B and C in comparison with the placebo group. Rate of complications after surgery was the same for all three groups and there was not any statistically meaningful difference in this regard. Chelledaghi herbal extract can be effectively used to mitigate pain after surgery in the selected patients without any significant side effects.
Department of Gynecology, Tabriz University of Medical Sciences, Tabriz, Iran.
Parvin Mostafa
PM
Gharabagy
Department of Gynecology, Tabriz University of Medical Sciences, Tabriz, Iran.
Poone
P
Zamany
Department of Pharmacology, Tabriz University of Medical Sciences, Tabriz, Iran.
Abbas
A
Delazar
Department of Physiology, Tabriz University of Medical Sciences, Tabriz, Iran.
Morteza
M
Ghojazadeh
Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohamad
M
Goldust
D000328:Adult; D000700:Analgesics / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects*; D007492:Iran; D019686:Lamiaceae; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis / Q000517:prevention & control*; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D010946:Plants, Medicinal; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome
D000700:Analgesics; D010936:Plant Extracts