Genetic characterization of porcine circovirus type 2 in the Korean wild boar population.
The porcine circovirus type 2 (PCV2) has reached very high levels in the pig population in South Korea and throughout the world since it was first described in the late 1990s. In this study, we found that the prevalence of PCV2 in the Korean wild boar population was 4.98% (91/1825). Interestingly, 19 PCV2 ORF2 sequences that could be completely sequenced showed that they belonged only to genotype PCV2b, subgroup 1A/B (n=16) and 1C (n=3). We suggest that sites potentially under positive selection are responsible for the antigenicity changes and phenotypic switch patterns in the capsid gene of 55 PCV2s from Korean domestic pigs, but the sites potentially under positive selection in the 19 PCV2 ORF2 genes from Korean wild boar are not responsible for antigenicity.
Virus Disease Division, Animal and Plant Quarantine Agency, Anyang, Gyeonggi-do, 430-824, Republic of Korea. Electronic address: andj67@korea.kr.
Dong-Jun
DJ
An
Virus Disease Division, Animal and Plant Quarantine Agency, Anyang, Gyeonggi-do, 430-824, Republic of Korea.
Seong-In
SI
Lim
Virus Disease Division, Animal and Plant Quarantine Agency, Anyang, Gyeonggi-do, 430-824, Republic of Korea.
Yong Kwan
YK
Kim
Virus Disease Division, Animal and Plant Quarantine Agency, Anyang, Gyeonggi-do, 430-824, Republic of Korea.
Hyun-Kyoung
HK
Lee
Virus Disease Division, Animal and Plant Quarantine Agency, Anyang, Gyeonggi-do, 430-824, Republic of Korea.
Yoon-Young
YY
Cho
Virus Disease Division, Animal and Plant Quarantine Agency, Anyang, Gyeonggi-do, 430-824, Republic of Korea.
Jae-Young
JY
Song
Virus Disease Division, Animal and Plant Quarantine Agency, Anyang, Gyeonggi-do, 430-824, Republic of Korea.
Bang-Hoon
BH
Hyun
College of Veterinary Medicine, Seoul National University, Seoul, 151-742, Republic of Korea.
Bong-Kyun
BK
Park
D000818:Animals; D000956:Antigens, Viral / Q000235:genetics; D036022:Capsid Proteins / Q000235:genetics; D017925:Circovirus / Q000235:genetics*; D005838:Genotype; D008969:Molecular Sequence Data; D010802:Phylogeny; D056910:Republic of Korea; D012641:Selection, Genetic; D034421:Sus scrofa / Q000821:virology; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000821:virology*
D000956:Antigens, Viral; D036022:Capsid Proteins
PCV2; PMAL; Phylogeny