One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.
State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Tang
T
Hai
1] State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China [2] University of Chinese Academy of Sciences, Beijing 100049, China.
Fei
F
Teng
State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Runfa
R
Guo
State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Wei
W
Li
State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Qi
Q
Zhou
D000483:Alleles; D000818:Animals; D030801:Animals, Genetically Modified; D001483:Base Sequence; D001760:Bleeding Time; D064130:CRISPR-Associated Proteins / Q000378:metabolism*; D064112:Clustered Regularly Interspaced Short Palindromic Repeats / Q000235:genetics*; D004624:Embryo Transfer; D005169:Factor VIII / Q000378:metabolism; D006801:Humans; D009154:Mutation; D012333:RNA, Messenger / Q000378:metabolism; D013552:Swine; D015053:Zygote / Q000166:cytology; D014841:von Willebrand Factor / Q000235:genetics / Q000378:metabolism
D064130:CRISPR-Associated Proteins; D012333:RNA, Messenger; D014841:von Willebrand Factor; D005169:Factor VIII