Efficient benzylic and aliphatic C-H oxidation with selectivity for methylenic sites catalyzed by a bioinspired manganese complex.
A benzimidazole-based nonheme manganese complex efficiently catalyzes benzylic, aliphatic C-H as well as tertiary C-H oxidation with hydrogen peroxide as the oxidant in the presence of acetic acid as additive. (18)O labeling experiments suggest the reaction may proceed via a high-valent manganese-oxo intermediate.
State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics , Chinese Academy of Sciences, Lanzhou, 730000, PR China.
Duyi
D
Shen
Chengxia
C
Miao
Shoufeng
S
Wang
Chungu
C
Xia
Wei
W
Sun
D001562:Benzimidazoles / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006861:Hydrogen Peroxide / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008345:Manganese / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction
D001562:Benzimidazoles; D009942:Organometallic Compounds; D008345:Manganese; D006861:Hydrogen Peroxide