Focal laser photocoagulation and photodynamic therapy for lupus choroidopathy.
OBJECTIVE
To describe the results of photodynamic therapy (PDT) and/or focal laser photocoagulation in the treatment of serous retinal detachments secondary to lupus choroidopathy.


METHODS
The medical records of three patients with serous detachments secondary to lupus choroidopathy who were treated with PDT and/or focal laser photocoagulation were reviewed. Concomitant systemic medical therapy as well as visual acuity and optical coherence tomography (OCT) outcomes were recorded.


RESULTS
All patients received systemic immunosuppressive therapy and had control of their extraocular manifestations prior to PDT and/or laser photocoagulation. One patient received only focal laser photocoagulation and had complete resolution of the subretinal fluid on OCT. The two other patients received a combination of PDT and focal laser treatment. One had improvement in vision and resolution of subretinal fluid on OCT. The second patient, who had longstanding lupus choroidopathy and associated subretinal fluid and macular edema, had only a significant decrease in fluid on OCT but no vision improvement.


CONCLUSIONS
In conjunction with control of systemic disease, PDT and/or focal laser photocoagulation can be successful in resolving subretinal fluid secondary to lupus choroidopathy.
1Uveitis and Retina Services, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Department of Ophthalmology, Boston, Massachusetts, USA.
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D000328:Adult; D015862:Choroid Diseases / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D017075:Laser Coagulation / Q000379:methods*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008269:Macular Edema / Q000209:etiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy / Q000379:methods*; D012163:Retinal Detachment / Q000209:etiology / Q000628:therapy; D041623:Tomography, Optical Coherence / Q000379:methods; D016896:Treatment Outcome; D014792:Visual Acuity
D007166:Immunosuppressive Agents
Photodynamic therapy; choroidopathy; focal laser photocoagulation; lupus