Completion of radiotherapy is associated with the Vulnerable Elders Survey-13 score in elderly patients with cancer.
OBJECTIVE
Vulnerability assessment of geriatric patients with cancer may contribute to improved anti-cancer treatment with maximal results and minimal side effects. The aim of the present study was to evaluate whether the Vulnerable Elders Survey-13 (VES-13) score is associated with completion of radiotherapy among elderly patients with cancer.


METHODS
This was a prospective observational study that included patients greater than age 75 with histologically confirmed cancer disease, referred to the Department of Radiation Oncology to receive radical or palliative radiotherapy, from 2010 to 2012. VES-13 forms were filled in before the initiation of radiotherapy and scores were assigned according to a standardized scoring procedure.


RESULTS
Of a total of 230 participants (median age 78.5 years), 41 (17.8%) did not complete radiotherapy. These patients had higher VES-13 scores (median with interquartile range: 5 [2-8.5]) compared to those who completed the treatment (3 [1-7]; P = 0.008). A VES-13 score >3 was associated with 2.14 times higher probability of not completing radiotherapy, whereas in patients with scores >7 this probability was 3.34 times higher. The association between higher VES-13 scores and non-completion of radiotherapy was independent of other factors, such as age, sex, comorbidities, type of radiotherapy, and presence of side effects.


CONCLUSIONS
Patients with higher VES-13 scores had increased probability of not completing radiotherapy in our study, and this effect was independent of other factors that might affect radiotherapy completion.
Department of Radiation Oncology, University of Patras Medical School, Greece.
Despina
D
Spyropoulou
Department of Medical Oncology, University General Hospital of Heraklion, Crete, Greece.
Athanasios G
AG
Pallis
Department of Public Health, University of Patras Medical School, Greece.
Michail
M
Leotsinidis
Department of Radiation Oncology, University of Patras Medical School, Greece. Electronic address: kardim@med.upatras.gr.
Dimitrios
D
Kardamakis
D000368:Aged; D000369:Aged, 80 and over; D019540:Area Under Curve; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000532:radiotherapy*; D010349:Patient Compliance / Q000706:statistics & numerical data*; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D035862:Vulnerable Populations
Cancer; Elderly; Radiotherapy; Vulnerable Elders Survey-13