Oncologic issues in the older adult in critical care.
This article describes the pathophysiologic changes that occur with aging as they relate to cancer and cytotoxic therapies, implications related to drug therapy, and complications of treatment modalities as they relate to older persons with cancer who may potentially be admitted to the intensive care unit. Knowledge of these issues is essential for health care providers, so that they can face the complex challenges and optimize the outcomes of critically ill older persons with cancer.
Department of Oncology, Emory University Hospital, 2184 Briarwood Bluff Northeast, Atlanta, GA 30319, USA. Electronic address: roberta.kaplow@emoryhealthcare.org.
Roberta
R
Kaplow
D000375:Aging / Q000502:physiology; D000970:Antineoplastic Agents / Q000378:metabolism / Q000493:pharmacokinetics / Q000494:pharmacology*; D015897:Comorbidity; D064648:Critical Care Nursing; D016638:Critical Illness / Q000453:epidemiology*; D004347:Drug Interactions; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000453:epidemiology*
D000970:Antineoplastic Agents
Cancer; Geriatrics; Older persons; Oncologic emergencies; Oncology