Low-dose dipyridamole treatment partially prevents diabetes mellitus-induced vascular endothelial and renal abnormalities in rats.
Department of Pharmacology, Rajendra Institute of Technology and Sciences (RITS), Sirsa 125 055, India.
Arun Kumar
AK
Sharma
Department of Pharmacology, Rajendra Institute of Technology and Sciences (RITS), Sirsa 125 055, India. Electronic address: 7drdeepa@gmail.com.
Deepa
D
Khanna
Pharmacology Unit, Faculty of Pharmacy, AIMST University, 08100 Bedong, Malaysia.
Pitchai
P
Balakumar
D000818:Animals; D003920:Diabetes Mellitus / Q000188:drug therapy* / Q000473:pathology; D004176:Dipyridamole / Q000008:administration & dosage*; D004730:Endothelium, Vascular / Q000187:drug effects* / Q000473:pathology; D005260:Female; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D051381:Rats; D017208:Rats, Wistar; D016896:Treatment Outcome
D010975:Platelet Aggregation Inhibitors; D004176:Dipyridamole
Diabetes mellitus; Low-dose dipyridamole; Nephropathy; PI3-K; Vascular endothelial dysfunction; eNOS