Impact of changes in Clostridium difficile testing practices on stool rejection policies and C. difficile positivity rates across multiple laboratories in the United States.
We describe the adoption of nucleic acid amplification tests (NAAT) for Clostridium difficile diagnosis and their impact on stool rejection policies and C. difficile positivity rates. Of the laboratories with complete surveys, 51 (43%) reported using NAAT in 2011. Laboratories using NAAT had stricter rejection policies and increased positivity rates.
Atlanta Research and Education Foundation, Atlanta, Georgia, USA.
Jessica
J
Cohen
Brandi
B
Limbago
Ghinwa
G
Dumyati
Stacy
S
Holzbauer
Helen
H
Johnston
Rebecca
R
Perlmutter
John
J
Dunn
Joelle
J
Nadle
Carol
C
Lyons
Erin
E
Phipps
Zintars
Z
Beldavs
Leigh Ann
LA
Clark
Fernanda C
FC
Lessa
D001431:Bacteriological Techniques / Q000379:methods*; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000175:diagnosis* / Q000382:microbiology*; D005243:Feces / Q000382:microbiology*; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D016134:Organizational Policy; D014481:United States