Association Between HTLV-I Infection with Chronic Lupoid Leishmaniasis.
OBJECTIVE
One of the different types of skin leishmaniasis is the Chronic Lupoid Leishmaniasis (CLL), which is caused by abnormal immune response. On the other hand, HTLV-I has been known to exist in some infectious diseases. Human T cell lymphotropic virus type1 (HTLV-I) and cutanous leishmaniasis exists endemically in Mashhad. The objective of this study was to evaluate the prevalence of HTLV-I in CLL patients.


METHODS
This cross sectional study involved 51 CLL patients admitted to cutaneous leishmaniasis clinics of Ghaem and Imam Reza hospitals in Mashhad, Iran. The blood samples were examined for serology tests through ELISA method.


RESULTS
The results of the experiments for evaluating the existence of HTLV-I in 51 patients under study in this research were proved to be negative.


CONCLUSIONS
According to this pilot study, the distribution of HTLV-I in CLL patients is not higher than normal population.
Research Centre for Skin Diseases and Cutaneous Leishmaniasis, Department of Dermatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Fakhrozaman
F
Pezeshkpoor
HTLV-I Foundation, Immunology Department, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyed Abdol Rahim
SA
Rezaei
Department of Internal Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Abbas
A
Shirdel
Department of Social Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad
M
Khajedaluee
Research Centre for Skin Diseases and Cutaneous Leishmaniasis, Department of Dermatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mansoreh
M
Alizadeh
Research Centre for Skin Diseases and Cutaneous Leishmaniasis, Department of Dermatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Javad
MJ
Yazdanpanah
Cutaneous lupoid leishmaniasis; Mashhad type 1 human T cell lymphotropic virus