Meigs' syndrome with elevated serum CA125 in a case of ovarian fibroma /thecoma.
BACKGROUND
CA125 levels in Meig's syndrome can increase or be normal which an unusual laboratory condition is. In this paper, we present a case of Meigs' syndrome associated with increased CA125 level due to ovarian fibroma / thecoma.


METHODS
A 50-year old Iranian woman presented with fever, abdominal pain and distention and in imaging assessment, a 90×109 mm heterogeneous pelvic mass with free abdominopelvic fluid was reported. Pleural effusion was detected in CXR. Aspiration of ascetic fluid showed no evidence of malignancy. CA125 level was greater than 600 IU/mL. The patient went under laparotomy in which a 120×100 mm mass was detected in her left adnexa attached to colon, bowels and bottom of pelvis. Histology reported ovarian fibro/ thecoma. The mass was resected and after that, the symptoms disappeared and CA125 level reached to 15 IU/mL. The patient had no problem after 18 months of follow up.


CONCLUSIONS
Meigs' syndrome should be considered at the differential diagnosis for a patient with pelvic mass, pleural effusion and ascites with normal cytology, increased CA125 levels.
Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran.
Shahla
S
Yazdani
Department of Surgery, Babol University of Medical Sciences, Babol, Iran.
Abolhasan
A
Alijanpoor
Department of Pathology, Babol University of Medical Sciences, Babol, Iran.
Majid
M
Sharbatdaran
Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran.
Zinatossadat
Z
Bouzari
Department of Nephrology, Mazandaran University of Medical Sciences, Sari, Iran.
Mohammad
M
Abedisamakoosh
Babol University of Medical Sciences, Babol, Iran.
Faranak
F
Lakaieandi
Babol University of Medical Sciences, Babol, Iran.
Mehdi
M
Mohammadpour
CA125; Meigs’ syndrome; fibro/thecoma.