Multiple cerebral infarction associated with neuroleptic-induced lupus anticoagulant.
A 39 year old schizophrenic woman with a 20 year history of neuroleptic treatment suffered bilateral cerebral infarcts and coagulation studies revealed a lupus anticoagulant (LA). She highlights the poorly recognized risk of thrombosis in patients on neuroleptics who develop LA. In this case the LA may have been induced by long-term therapy with haloperidol, a novel and potentially important association.
University Department of Psychiatry, Northern General Hospital, Herries Road, Sheffield S5 7AU, UK.
J D
JD
Laugharne
Cerebral infarction; Haloperidol; Lupus anticoagulant; Neuroleptics