Carcinosarcoma of the Female Urethra.
Carcinosarcoma is a rare malignant tumor with a biphasic morphology characterized by the presence of a malignant epithelial and mesenchymal component. It has been reported in many organs, including the genitourinary tract. We describe a case of a 47-year-old woman admitted to our hospital for history of recurrent urinary tract infection, dysuria and discharge of bloody fluid from the urethra at the end of urination. A tender palpable mass under the anterior vaginal wall was found and pathological examination showed a urethral carcinosarcoma. The histopathogenetic hypothesis and clinical management were considered in this report.
Urology Unit and Pathology Unit, Cannizzaro Hospital, Catania, Italy.
L
L
D''Arrigo
A
A
Costa
F
F
Fraggetta
M
M
Pennisi
P
P
Pepe
F
F
Aragona
D002296:Carcinosarcoma / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology*; D002945:Cisplatin / Q000008:administration & dosage; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D020360:Neoadjuvant Therapy / Q000379:methods; D009364:Neoplasm Recurrence, Local; D011123:Polyploidy; D049268:Positron-Emission Tomography; D014516:Ureteral Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology*; D014521:Urethra / Q000473:pathology*
D002945:Cisplatin