Silver-mediated radical aryltrifluoromethylthiolaton of activated alkenes.
The first example of silver-mediated oxidative aryltrifluoromethylthiolation of activated alkenes to produce valuable trifluoromethylthiole-containing oxindoles was developed. Mechanistic investigations indicated that this novel transformation proceeded through a unique F3CS(•) radical addition path, thus providing a practical and easy-handling method to generate a F3CS(•) radical in the laboratory.
Department of Chemistry, University of Science and Technology of China , 96 Jinzhai Road, Hefei, Anhui 230026, China.
Feng
F
Yin
Xi-Sheng
XS
Wang