Diagnosis and classification of adult Still's disease.
The cornerstone of adult onset Still's disease is the triad of daily fever, arthritis and rash. This syndrome remains enigmatic and most often a disease of exclusion. There are both musculoskeletal as well as systemic features. More importantly, reactive hemophagocytic syndrome may occur in patients. In this review we attempt to place this syndrome in perspective, including data on geoepidemiology, clinical and laboratory features.
Department of Medicine 'B', Sheba Medical Center, Tel-Hashomer, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Naim
N
Mahroum
Department of Medicine 'B', Sheba Medical Center, Tel-Hashomer, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Hussein
H
Mahagna
Department of Medicine 'B', Sheba Medical Center, Tel-Hashomer, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic address: hamital@netvision.net.il.
Howard
H
Amital
D001168:Arthritis / Q000145:classification / Q000175:diagnosis; D001327:Autoimmune Diseases / Q000145:classification / Q000175:diagnosis / Q000276:immunology; D016470:Bacteremia / Q000145:classification / Q000175:diagnosis / Q000276:immunology; D057210:Delayed Diagnosis; D003937:Diagnosis, Differential; D005076:Exanthema / Q000145:classification / Q000175:diagnosis; D005335:Fever of Unknown Origin / Q000145:classification / Q000175:diagnosis; D006801:Humans; D007249:Inflammation / Q000145:classification / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D051359:Lymphohistiocytosis, Hemophagocytic / Q000145:classification / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D009139:Musculoskeletal Abnormalities / Q000145:classification / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D012189:Retrospective Studies; D016706:Still's Disease, Adult-Onset / Q000145:classification* / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D014777:Virus Diseases / Q000145:classification / Q000175:diagnosis / Q000276:immunology
Arthritis; Cytokines; Fever; Rash; Still's disease; fever of unknown origin