Lipoprotein (a): More than a bystander in the etiology of hypertension? A study on essential hypertensive patients not yet on treatment.
BACKGROUND
Hypertension (HTN) is a very common disorder with a substantial impact on public health because of its complications.


OBJECTIVE
To study the association of serum lipoprotein(a) [Lp(a)] elevation with essential hypertension (eHTN).


METHODS
This study was conducted on a group of essential hypertensive patients. Laboratory exams consisting of serum creatinine and Lp(a) were measured.


RESULTS
Ninety five essential hypertensive patients were enrolled to the study. Serum LP (a) in patients was 46.5±20. In patients an inverse correlation between serum Lp(a) andcreatinine clearance was seen (r = -0.175 p<0.05). There was a significant correlation between serum Lp(a) and age (r =0.191 p<0.05) or duration of HTN (known duration of hypertension period) (r =0.362 p<0.05).


CONCLUSIONS
Our data suggest that Lp(a) may be involved as a cofactor in essential hypertension, with a mechanism that remains to be elucidated.
Department of Nephrology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Ali
A
Ghorbani
Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Mahmoud
M
Rafieian-Kopaei
Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Hamid
H
Nasri
Essential hypertension; Lipoprotein (a); Renal failure