An autopsy case of malignant pleural mesothelioma associated with nephrotic syndrome.
A 64-year-old man who had been exposed to asbestos was referred to our hospital for a detailed examination of left pleural effusion. A laboratory examination of the urine and blood revealed nephrotic syndrome. A thoracoscopic examination did not yield a definitive diagnosis. Twenty months later, a left pleural tumor became apparent, and the patient died of respiratory failure and cachexia. An autopsy revealed epithelioid malignant pleural mesothelioma. The glomeruli appeared normal under light microscopy. A review of the English literature revealed only three reports of malignant mesothelioma associated with minimal-change nephrotic syndrome. The natural course of malignant mesothelioma with nephrotic syndrome has not been previously reported.
Department of Respiratory Medicine, Hamamatsu Rosai Hospital, Japan.
Seiichiro
S
Suzuki
Mikio
M
Toyoshima
Fumiya
F
Nihashi
Hiroe
H
Tsukui
Satoshi
S
Baba
Haruhiko
H
Sugimura
Takafumi
T
Suda
D001194:Asbestos / Q000009:adverse effects*; D001344:Autopsy; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis* / Q000209:etiology; D000086002:Mesothelioma, Malignant; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000175:diagnosis* / Q000209:etiology; D016273:Occupational Exposure / Q000009:adverse effects*; D010997:Pleural Neoplasms / Q000175:diagnosis* / Q000209:etiology
D001194:Asbestos