Advances of research on glycinin and β-conglycinin: a review of two major soybean allergenic proteins.
Being an important crop, soybean is widely used in the world and plays a vital role in human and animal nutrition. However, it contains several antinutritional factors (ANFs) including soybean agglutinin, soybean protease inhibitors, soybean allergenic proteins, etc., that may result in poor food utilization, decreased growth performance, and even disease. Among these ANFs, soybean allergenic proteins can lead to allergic reactions in human and animals, which has become a public problem all over the world, but our knowledge on it is still inadequate. This paper aims to provide an update on the characteristics, detection or exploration methods, and in vivo research models of soybean allergenic proteins; especially glycinin and β-conglycinin are deeply discussed. Through this review, we may have a better understanding on the advances of research on these two soybean allergenic proteins. Besides, the ingredient processing used to reduce the allergenicity of soybean is also reviewed.
a College of Animal Science and Technology , Jilin Agricultural University , Changchun , 130118 , P. R. China.
Tao
T
Wang
Gui-Xin
GX
Qin
Ze-Wei
ZW
Sun
Yuan
Y
Zhao
D000485:Allergens; D000818:Animals; D052179:Antigens, Plant / Q000032:analysis / Q000737:chemistry / Q000276:immunology; D004195:Disease Models, Animal; D005285:Fermentation; D005511:Food Handling / Q000379:methods; D005512:Food Hypersensitivity; D005916:Globulins / Q000032:analysis / Q000737:chemistry / Q000276:immunology; D006801:Humans; D051379:Mice; D023421:Models, Animal; D051381:Rats; D055314:Seed Storage Proteins / Q000032:analysis / Q000737:chemistry / Q000276:immunology; D030262:Soybean Proteins / Q000032:analysis / Q000737:chemistry / Q000276:immunology; D013025:Glycine max / Q000276:immunology*; D013552:Swine
D000485:Allergens; D052179:Antigens, Plant; D005916:Globulins; D055314:Seed Storage Proteins; D030262:Soybean Proteins; C013894:beta-conglycinin protein, Glycine max; C011474:glycinin