Mapping the temporal pole with a specialized electrode array: technique and preliminary results.
Temporopolar cortex plays a crucial role in the pathogenesis of temporal lobe epilepsy and subserves important cognitive functions. Because of its shape and position in the middle cranial fossa, complete electrode coverage of the temporal pole (TP) is difficult to achieve using existing devices. We designed a novel TP electrode array that conforms to the surface of temporopolar cortex and achieves dense electrode coverage of this important brain region. A multi-pronged electrode array was designed that can be placed over the surface of the TP using a straightforward insertion technique. Twelve patients with medically intractable epilepsy were implanted with the TP electrode array for purposes of seizure localization. Select patients underwent cognitive mapping by electrocorticographic (ECoG) recording from the TP during a naming task. Use of the array resulted in excellent TP electrode coverage in all patients. High quality ECoG data were consistently obtained for purposes of delineating seizure activity and functional mapping. During a naming task, significant increases in ECoG power were observed within localized subregions of the TP. One patient developed a transient neurological deficit thought to be related to the mass effect of multiple intracranial recording arrays, including the TP array. This deficit resolved following removal of all electrodes. The TP electrode array overcomes limitations of existing devices and enables clinicians and researchers to obtain optimal multi-site recordings from this important brain region.
Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.
Taylor J
TJ
Abel
Ariane E
AE
Rhone
Kirill V
KV
Nourski
Mark A
MA
Granner
Hiroyuki
H
Oya
Timothy D
TD
Griffiths
Daniel T
DT
Tranel
Hiroto
H
Kawasaki
Matthew A
MA
Howard
D000328:Adult; D001927:Brain Diseases / Q000209:etiology; D001931:Brain Mapping / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D004567:Electrodes, Implanted / Q000009:adverse effects; D004569:Electroencephalography / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D004827:Epilepsy / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012640:Seizures / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D013702:Temporal Lobe / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D055815:Young Adult