A novel 6-hydroxy-8,11,11-trimethyl-bicyclo[7.2.0]undec-4-ene-4-carboxylic acid: a potent antioxidant agent from Iphiona scabra.
A novel 6-hydroxy-8,11,11-trimethyl-bicyclo[7.2.0]undec-4-ene-4-carboxylic acid 1 has been isolated from leaves of Iphiona scabra DC. Its structure has been established on the basis of chemical and physical evidence (IR, ¹H NMR, ¹³C NMR, and MS) and further confirmed by single-crystal X-ray diffraction study. The in vitro antioxidant activities of isolated compound 1 and extracts were evaluated by 1,1-diphenyl-2-picrylhydrazyl method.
a Department of Chemistry , Aligarh Muslim University , Aligarh 202002 , India.
Mehtab
M
Parveen
Shaista
S
Azaz
Akhtar
A
Ali
Omer A
OA
Basudan
P S
PS
Pereira Silva
Consuelo Y
CY
Vivas
D000465:Algorithms; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D019659:Asteraceae / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000494:pharmacology; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D002264:Carboxylic Acids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D018360:Crystallography, X-Ray; D008070:Lipopolysaccharides / Q000494:pharmacology; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D008968:Molecular Conformation; D015394:Molecular Structure; D009569:Nitric Oxide / Q000096:biosynthesis; D019906:Nuclear Magnetic Resonance, Biomolecular; D010084:Oxidation-Reduction; D010851:Picrates / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D015006:Yemen
C000588521:6-hydroxy-8,11,11-trimethyl-bicyclo(7.2.0)undec-4-ene-4-carboxylic acid:; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000975:Antioxidants; D001713:Biphenyl Compounds; D019086:Bridged Bicyclo Compounds, Heterocyclic; D002264:Carboxylic Acids; D008070:Lipopolysaccharides; D010851:Picrates; D009569:Nitric Oxide; C004931:1,1-diphenyl-2-picrylhydrazyl