An amyloid inhibitor octapeptide forms amyloid type fibrous aggregates and affects microtubule motility.
An amyloid inhibitor octapeptide simultaneously forms amyloid type fibrous aggregates on its own and interacts with the microtubule lattice three times stronger than a Xenopus Microtubule Associated Protein (XMAP215).
Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata-700032, West Bengal, India. sghosh@iicb.res.in.
Atanu
A
Biswas
Prashant
P
Kurkute
Batakrishna
B
Jana
Aparna
A
Laskar
Surajit
S
Ghosh
D000595:Amino Acid Sequence; D000682:Amyloid / Q000037:antagonists & inhibitors*; D002465:Cell Movement; D046529:Microscopy, Electron, Transmission; D008869:Microtubule-Associated Proteins / Q000737:chemistry / Q000378:metabolism; D008870:Microtubules / Q000502:physiology*; D008969:Molecular Sequence Data; D011485:Protein Binding; D017550:Spectroscopy, Fourier Transform Infrared
D000682:Amyloid; D008869:Microtubule-Associated Proteins