Effect of change in macular birefringence imaging protocol on retinal nerve fiber layer thickness parameters using GDx VCC in eyes with macular lesions.
This study evaluates the effect of two macular birefringence protocols (bow-tie retardation and irregular macular scan) using GDx VCC on the retinal nerve fiber layer (RNFL) thickness parameters in normal eyes and eyes with macular lesions. In eyes with macular lesions, the standard protocol led to significant overestimation of RNFL thickness which was normalized using the irregular macular pattern protocol. In eyes with normal macula, absolute RNFL thickness values were higher in irregular macular pattern protocols with the difference being statistically significant for all parameters except for inferior average thickness. This has implications for monitoring glaucoma patients who develop macular lesions during the course of their follow-up.
Glaucoma Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Tanuj
T
Dada
Sana I
SI
Tinwala
Vivek
V
Dave
Anand
A
Agarwal
Reetika
R
Sharma
Meenakshi
M
Wadhwani
D000328:Adult; D001718:Birefringence; D016022:Case-Control Studies; D002985:Clinical Protocols; D003430:Cross-Sectional Studies; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D007834:Lasers; D008266:Macula Lutea / Q000473:pathology*; D009412:Nerve Fibers / Q000473:pathology*; D009887:Ophthalmoscopy / Q000379:methods*; D012164:Retinal Diseases / Q000473:pathology*; D012165:Retinal Ganglion Cells / Q000473:pathology*