Comparison of the long-term results of Roux-en-Y gastric bypass and sleeve gastrectomy for morbid obesity: a systematic review and meta-analysis of randomized and nonrandomized trials.
OBJECTIVE
Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are 2 of the most widely used bariatric procedures today, in this meta-analysis, both techniques were compared for evaluating the efficacy and safety of the treatment of morbid obesity.


METHODS
Systematic literature search of Cochrane Controlled Trials Register Databases, Medline, Embase, ISI databases, and Chinese Biomedical Literature Database was performed. Statistical analyses were carried out using RevMan software.


RESULTS
Thirty-two recent studies including 6526 patients in total were included in this meta-analysis. Compared with SG, RYGB had significantly better effect in resolving type 2 diabetes mellitus, hypertension, hypercholesterolemia, gastroesophageal reflux disease, and arthritis. However, RYGB had higher incidence of complications and reoperation, and longer operation time than SG.


CONCLUSIONS
RYGB was more effective than SG in the resolution of obesity-related comorbidities, SG was a safer procedure with a reduced rate of complications and reoperation.
Department of Gastrointestinal Surgery, the First People's Hospital of Xiaoshan, Hangzhou Normal University, Hangzhou, People's Republic of China.
Jian-Fang
JF
Li
Dan-Dan
DD
Lai
Zhi-Hong
ZH
Lin
Tian-Ye
TY
Jiang
Ai-Min
AM
Zhang
Jian-Feng
JF
Dai
D005743:Gastrectomy; D015390:Gastric Bypass; D006801:Humans; D009767:Obesity, Morbid / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome