Ocean acidification slows retinal function in a damselfish through interference with GABAA receptors.
Vision is one of the most efficient senses used by animals to catch prey and avoid predators. Therefore, any deficiency in the visual system could have important consequences for individual performance. We examined the effect of CO2 levels projected to occur by the end of this century on retinal responses in a damselfish, by determining the threshold of its flicker electroretinogram (fERG). The maximal flicker frequency of the retina was reduced by continuous exposure to elevated CO2, potentially impairing the capacity of fish to react to fast events. This effect was rapidly counteracted by treatment with a GABA antagonist (gabazine), indicating that GABAA receptor function is disrupted by elevated CO2. In addition to demonstrating the effects of elevated CO2 on fast flicker fusion of marine fishes, our results show that the fish retina could be a model system to study the effects of high CO2 on neural processing.
Queensland Brain Institute, University of Queensland, Brisbane 4072, Australia.
Wen-Sung
WS
Chung
N Justin
NJ
Marshall
Sue-Ann
SA
Watson
Philip L
PL
Munday
Göran E
GE
Nilsson
D000818:Animals; D002245:Carbon Dioxide / Q000032:analysis / Q000378:metabolism*; D057231:Climate Change; D009792:Oceans and Seas; D010473:Perciformes / Q000502:physiology*; D011963:Receptors, GABA-A / Q000378:metabolism*; D012160:Retina / Q000502:physiology* / Q000503:physiopathology; D012623:Seawater / Q000737:chemistry*; D014785:Vision, Ocular
D011963:Receptors, GABA-A; D002245:Carbon Dioxide
Carbon dioxide; Coral reef; Electroretinogram; Flicker fusion frequency; Vision