Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection.
The chemical synthesis of staphyloferrin A, a siderophore used by Staphylococcus bacteria for ferric iron retrieval, has been achieved with 79% yield via solid phase peptide synthesis (SPPS). Biological activity of synthetic staphyloferrin A has been confirmed by demonstrating its capture and uptake by live S. aureus.
Department of Chemistry, Purdue University, 560 Oval Dr, West Lafayette, IN 47907, USA. rkpandey1@yahoo.com plow@purdue.edu.
Rajesh K
RK
Pandey
Gregory G
GG
Jarvis
Philip S
PS
Low
D002951:Citrates / Q000032:analysis*; D009952:Ornithine / Q000031:analogs & derivatives* / Q000032:analysis; D013211:Staphylococcus aureus / Q000302:isolation & purification*
D002951:Citrates; C063851:staphyloferrin A; D009952:Ornithine