A 2D DNA lattice as an ultrasensitive detector for beta radiations.
There is growing demand for the development of efficient ultrasensitive radiation detectors to monitor the doses administered to individuals during therapeutic nuclear medicine which is often based on radiopharmaceuticals, especially those involving beta emitters. Recently biological materials are used in sensors in the nanobio disciplines due to their abilities to detect specific target materials or sites. Artificially designed two-dimensional (2D) DNA lattices grown on a substrate were analyzed after exposure to pure beta emitters, (90)Sr-(90)Y. We studied the Raman spectra and reflected intensities of DNA lattices at various distances from the source with different exposure times. Although beta particles have very low linear energy transfer values, the significant physical and chemical changes observed throughout the extremely thin, ∼0.6 nm, DNA lattices suggested the feasibility of using them to develop ultrasensitive detectors of beta radiations.
Department of Physics, ‡Sungkyunkwan Advanced Institute of Nanotechnology (SAINT), §School of Mechanical Engineering, ∥Department of Energy Science, and ⊥School of Electronics and Electrical Engineering, Sungkyunkwan University , Suwon 440-746, Korea.
Sreekantha Reddy
SR
Dugasani
Jang Ah
JA
Kim
Byeonghoon
B
Kim
Pranav
P
Joshirao
Bramaramba
B
Gnapareddy
Chirag
C
Vyas
Taesung
T
Kim
Sung Ha
SH
Park
Vijay
V
Manchanda
D001610:Beta Particles; D004247:DNA / Q000737:chemistry*; D057230:Limit of Detection; D018625:Microscopy, Atomic Force
D004247:DNA