The optimal timing to perform 18F/11C-choline PET/CT in patients with suspicion of relapse of prostate cancer: trigger PSA versus PSA velocity and PSA doubling time.
In the present short communication we considered the main publications focused on trigger prostate-specific antigen (PSA) and PSA kinetics that systematically compared 18F to 11C-choline PET/CT in order to establish the optimal time to perform choline PET/CT in relation to the trigger values and velocity, as well as doubling time of PSA serum levels.
1 Department of Nuclear Medicine and Molecular Imaging, IRCCS Neuromed, Pozzilli, Isernia - Italy.
Ferdinando
F
Calabria
Domenico
D
Rubello
Orazio
O
Schillaci
D002250:Carbon Radioisotopes; D002794:Choline / Q000031:analogs & derivatives; D005462:Fluorine Radioisotopes; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography / Q000379:methods*; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D011859:Radiography
D002250:Carbon Radioisotopes; D005462:Fluorine Radioisotopes; C516370:fluoromethylcholine; D017430:Prostate-Specific Antigen; D002794:Choline