Estrogen up-regulates CRHR2 expression via demethylation of CRHR2 gene promoter in cardiomyocytes.
Department of Physiology, Second Military Medical University, Shanghai 200433, China.
Binhai
B
Cong
Department of Physiology, Second Military Medical University, Shanghai 200433, China. Electronic address: nixinsmmu@hotmail.com.
Xin
X
Ni
D002460:Cell Line; D019175:DNA Methylation; D004958:Estradiol / Q000494:pharmacology*; D006801:Humans; D032383:Myocytes, Cardiac / Q000187:drug effects* / Q000378:metabolism; D011401:Promoter Regions, Genetic; D012333:RNA, Messenger / Q000378:metabolism; D060888:Real-Time Polymerase Chain Reaction; D018019:Receptors, Corticotropin-Releasing Hormone / Q000235:genetics*; D015854:Up-Regulation
C101531:CRF receptor type 2; D012333:RNA, Messenger; D018019:Receptors, Corticotropin-Releasing Hormone; D004958:Estradiol
Corticotropin-releasing hormone Receptor type 2; Estrogen; Methylation