Gynecologic sarcoma: a clinico-pathological review.
Most of the cases showing good prognosis in literature are probably intermediate tumors between benign and malignant of undetermined malignant potential (UMP) and other tumors with intermediate features which are currently not considered among sarcomas. Misdiagnosis of a malignant lesion as a benign one has a tragic outcome for the patient. Best therapic choice for sarcomas remains surgery, while chemotherapy (CTX) and radiation therapy (RT) could be used in adjuvant settings. A major effort should be played in the understanding of biological features and behavior of the disease to address a better clinical practice. Uterine sarcomas are rare gynecological tumors; their incidence has been increasing during the last few years.
Department of Obstetrics, Gynecology, and Urology, Sapienza University of Rome, Sant'Andrea Hospital, Rome, Italy. enzo.ricciardi@uniroma1.it
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Ricciardi
Department of Obstetrics, Gynecology, and Urology, Sapienza University of Rome, Sant'Andrea Hospital, Rome, Italy.
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Maniglio
Department of Obstetrics, Gynecology, and Urology, Sapienza University of Rome, Sant'Andrea Hospital, Rome, Italy.
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Marziani
Department of Obstetrics, Gynecology, and Urology, Sapienza University of Rome, Sant'Andrea Hospital, Rome, Italy.
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Frega
Department of Obstetrics, Gynecology, and Urology, Sapienza University of Rome, Sant'Andrea Hospital, Rome, Italy.
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Moscarini
D005260:Female; D005833:Genital Neoplasms, Female / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D006801:Humans; D011379:Prognosis; D012509:Sarcoma / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy