Ultrasound-guided vacuum-assisted breast biopsy using Mammotome biopsy system for detection of breast cancer: results from two high volume hospitals.
Ultrasound-guided vacuum-assisted breast biopsy (VABB) has been recently regarded as a feasible, effective, minimally invasive and safe method for removal of benign breast lesions without serious complications. The frequency of detection of noninvasive malignant breast lesions by ultrasound-guided VABB is increasing. The aim of this study was to evaluate the role of the ultrasound-guided VABB using Mammotome biopsy system in the early detection of breast cancer. Retrospective review between January 2008 to March 2013 the First Affiliated Hospital, Zhejiang University School of Medicine and Taizhou Hospital, Wenzhou Medical College. From January 2008 to March 2013, a total of 5232 ultrasound-guided VABB procedures were performed in 3985 patients whose mean ages were 36.3 years (range: 16-73). The histological results of 5232 ultrasound-guided VABB were retrospectively reviewed. Ultrasonography follow-up was performed at 3 to 6 month intervals in order to assess recurrence. Two hundred twenty three high risk lesions (comprising 59 papilloma, 57 papillomatosis, and 107 atypical hyperplasia) and 61 malignant lesions (comprising 23 ductal carcinoma in situ, 21 lobular carcinoma in situ, 12 infiltrating ductal carcinoma, and 5 infiltrating mucinous carcinoma) were identified. Sensitivity (100%) and diagnostic accuracy (100%) regarding the detection of malignancy were excellent for ultrasound-guided VABB using Mammotome biopsy system. Our results indicate that ultrasound-guided VABB using Mammotome biopsy system is an accurate technique for the sampling, diagnosis, and early detection of breast cancer. It is recommended that the Mammotome biopsy system could be as the method of choice for detecting nonpalpable early breast cancer.
Operating Room, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou Zhejiang 310003, China.
Shaobo
S
Pan
Department of Emergency Surgery, Linyi People's Hospital Linyi, Shandong 276000, China.
Wenguang
W
Liu
Department of Surgical Oncology, Taizhou Hospital, Wenzhou Medical College Linhai, Zhejiang 317000, China.
Ketao
K
Jin
Department of Breast Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine Hangzhou, Zhejiang 310003, China.
Yu
Y
Liu
Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine Hangzhou, Zhejiang 310003, China.
Yunxiao
Y
Zhou
Mammotome biopsy; Vacuum-assisted biopsy; breast cancer; early diagnosis; ultrasound guidance