Electrochemical thrombin detection based on the direct interaction of target proteins and graphene oxide as an indicator.
Target protein-directed adsorption of graphene oxide (GO) as an electroactive indicator was employed for electrochemical detection of thrombin. The method was highly sensitive and the detection limit was as low as 9.7 pg ml(-1).
Department of Chemistry, Incheon National University, Incheon 406-772, Republic of Korea. kyuwon_kim@incheon.ac.kr.
Dongcheol
D
Choi
Hanall
H
Jeong
Kyuwon
K
Kim
D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques / Q000295:instrumentation*; D055664:Electrochemical Techniques / Q000295:instrumentation*; D004867:Equipment Design; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D010087:Oxides / Q000737:chemistry*; D013917:Thrombin / Q000032:analysis*
D052157:Aptamers, Nucleotide; D010087:Oxides; C081676:thrombin aptamer; D006108:Graphite; D013917:Thrombin