A new quaternary protoberberine alkaloid isolated from Dicranostigma leptopodum (Maxim) Fedde.
Phytochemical investigation of the whole plants of Dicranostigma leptopodum (Maxim) Fedde has led to the isolation of two quaternary protoberberine alkaloids 5-hydroxy-coptisine (1) and berberrubine (2). This type of alkaloids was isolated from the genus Dicranostigma for the first time and the new compound structure (1) was elucidated by various spectroscopic methods including 2D NMR techniques (gCOSY, HMQC and HMBC) and HR-ESI-MS.
a Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province , Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences , Lanzhou 73000 , P.R. China.
Mei
M
Zhong
Yu-Xi
YX
Ma
Jun-Xi
JX
Liu
Duo-Long
DL
Di
D001599:Berberine / Q000031:analogs & derivatives; D001600:Berberine Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D028101:Papaveraceae / Q000737:chemistry*
C000591571:5-hydroxycoptisine; D001600:Berberine Alkaloids; D004365:Drugs, Chinese Herbal; C034384:coptisine; D001599:Berberine; C115958:berberrubine; C009090:protoberberine