Synthesis and characterization of functional multicomponent nanosized gallium chelated gold crystals.
In this communication, we describe a novel synthetic method for fabricating multicomponent gold nanoparticles containing both gallium ions and biomolecules on the surface. Detailed compositional analysis, using STEM-HAADF and EELS spectroscopy, confirmed the crystalline nature of gold and chelation of gallium ions. The presence of the biomolecule was validated using conventional ELISA.
Department of Radiology, University of Missouri-Columbia, Columbia, Missouri-65212, USA. kannanr@health.missouri.edu.
Ajit
A
Zambre
Francisco
F
Silva
Anandhi
A
Upendran
Zahra
Z
Afrasiabi
Yan
Y
Xin
António
A
Paulo
Raghuraman
R
Kannan
D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D002614:Chelating Agents / Q000737:chemistry* / Q000494:pharmacology; D005708:Gallium / Q000737:chemistry* / Q000494:pharmacology; D006046:Gold / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D053768:Metal Nanoparticles / Q000008:administration & dosage / Q000737:chemistry*; D004369:Pentetic Acid / Q000737:chemistry* / Q000494:pharmacology
D002614:Chelating Agents; D006046:Gold; D004369:Pentetic Acid; D005708:Gallium