Xanthogranulomatous osteomyelitis of rib mimicking malignant lesions in (18)F-FDG PET/CT imaging: a report of two cases.
Xanthogranulomatous osteomyelitis is a rare inflammatory process characterized histologically by collection of foamy macrophages admixed with mononuclear cells. We describe 2 cases with chest and back pain; radiography and CT scan identified expansile osteolytic rib destructive lesions with soft tissue mass. F-FDG PET/CT revealed accumulation of F-FDG similar to malignancy. Xanthogranulomatous osteomyelitis was histologically confirmed with numerous foamy histiocytes admixed with inflammatory infiltrate.
From the *Department of Nuclear Medicine, Qilu Hospital, Shandong University, Jinan; and Departments of †PET/CT, ‡Nuclear Medicine, and §Occupational Disease, Qingdao City Center Hospital, Qingdao, China.
Yan-Li
YL
Wang
Hua
H
Yu
Hua
H
Zhang
Xin-Jian
XJ
Cui
Jian-Kui
JK
Han
D003937:Diagnosis, Differential; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D010019:Osteomyelitis / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D012272:Ribs / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed
D019788:Fluorodeoxyglucose F18