There are not enough data to conclude that Monomethylsilanetriol is safe.
: This article is in response to Jugdaohsingh et al.: The silicon supplement 'Monomethylsilanetriol' is safe and increases the body pool of silicon in healthy Pre-menopausal women. Nutrition & Metabolism 2013 10:37: http://www.nutritionandmetabolism.com/content/10/1/37 The response from the authors is published as Jugdaohsingh et al.: Response to Prof D. Vanden Berghe letter: 'There are not enough data to conclude that Monomethylsilanetriol is safe'. Nutrition & Metabolism 2013 10:65: http://www.nutritionandmetabolism.com/content/10/1/65 ABSTRACT: The authors claim that the silicon supplement 'Monomethylsilanetriol' (MMST) is safe and is converted to orthosilicic acid (OSA) after ingestion. Critical analysis of the study results indicates that the presented data are insufficient to conclude that the use of MMST in food or food supplements is safe. Long term safety studies in humans and toxicological testing in vitro and in animals are an absolute requisite for such a conclusion but these are lacking in the present study and in the literature. Furthermore, none of the presented data show that MMST is actually converted to OSA, as OSA was not analyzed in neither serum or urine of supplemented subjects.
Department of Pharmaceutical Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium. dirk.vandenberghe@ua.ac.be.
Dirk A
DA
Vanden Berghe