Neuroendocrine regulation of inflammation.
The interaction between the sympathetic nervous system and the immune system has been documented over the last several decades. In this review, the neuroanatomical, cellular, and molecular evidence for neuroimmune regulation in the maintenance of immune homeostasis will be discussed, as well as the potential impact of neuroimmune dysregulation in health and disease.
The Biomedical Sciences Graduate Program, The Ohio State University Wexner College of Medicine, Columbus, OH 43210, United States. Electronic address: padro.5@osu.edu.
Caroline J
CJ
Padro
The Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University Wexner College of Medicine, Columbus, OH 43210, United States; The Institute of Behavioral Medicine Research, The Ohio State University Wexner College of Medicine, Columbus, OH 43210, United States. Electronic address: Virginia.sanders@osumc.edu.
Virginia M
VM
Sanders
D001249:Asthma / Q000235:genetics* / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D016207:Cytokines / Q000235:genetics / Q000276:immunology; D003713:Dendritic Cells / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D005786:Gene Expression Regulation; D006706:Homeostasis / Q000235:genetics / Q000276:immunology; D006801:Humans; D007107:Immune System / Q000378:metabolism*; D008214:Lymphocytes / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D009638:Norepinephrine / Q000235:genetics / Q000276:immunology; D018410:Pneumonia, Bacterial / Q000235:genetics* / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D018343:Receptors, Adrenergic, beta-2 / Q000235:genetics / Q000276:immunology; D015398:Signal Transduction; D013119:Spinal Cord Injuries / Q000235:genetics* / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D013312:Stress, Physiological; D013564:Sympathetic Nervous System / Q000276:immunology*
D016207:Cytokines; D018343:Receptors, Adrenergic, beta-2; D009638:Norepinephrine
Adrenergic receptor; Beta2-adrenergic receptor; Neuroimmune; Norepinephrine; Stress; Sympathetic nervous system