Lymphangioma circumscriptum, angiokeratoma, or superficial vascular ectasia with epithelial hyperplasia?
We report a case of lymphangioma circumscriptum (cavernous lymphangioma with epithelial hyperplasia) in a 12-year-old girl, presenting as a papillary tumor on the right dorsal side of her tongue. Microscopic examination found cavernous vascular channels lined by a single layer of CD31(+), podoplanin-positive, CD34(-) endothelial cells that occupied the papillary lamina propria and were accompanied by epithelial hyperplasia. A review of the literature on oral vascular tumors with epithelial hyperplasia, namely, lymphangioma circumscriptum and angiokeratoma, provided information that draws into question the use of these terms.
Graduate Student and Scholar of Alexander Onassis Foundation, Department of Oral Pathology, Faculty of Dentistry, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: nikolaoskatsoulas@gmail.com.
Nikolaos
N
Katsoulas
Assistant Professor, Department of Oral Pathology, Faculty of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos I
KI
Tosios
Graduate Student, Department of Oral Pathology, Faculty of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
Prokopios
P
Argyris
Associate Professor, Division of Oral Pathology, Dental School, University of Minnesota, Minneapolis, MN, USA.
Ioannis G
IG
Koutlas
Professor, Department of Oral Pathology, Faculty of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
Alexandra
A
Sklavounou
D000794:Angiokeratoma / Q000473:pathology* / Q000601:surgery; D002648:Child; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D008202:Lymphangioma / Q000473:pathology* / Q000601:surgery; D014059:Tongue / Q000098:blood supply* / Q000473:pathology* / Q000601:surgery; D014062:Tongue Neoplasms / Q000473:pathology* / Q000601:surgery