Palladium-catalysed inter- and intramolecular formation of C-O bonds from allenes.
The Pd-catalysed formation of a C-O bond from allenes mainly occurs via the inter- or intramolecular reaction with a hydroxyl group belonging to an alcohol, a phenol or an acid. A carbonyl or a carbonate entity can also be involved. In most cases, the formation of the C-O bond is one step of a domino reaction leading also to a C-C or C-N bond, or to another C-O bond. Thus, a wide range of products, in particular highly functionalized heterocycles, have been synthesised. Catalytic cycles have been proposed but the mechanisms often remain speculative.
Institut de Chimie Moléculaire de Reims, UMR 7312, CNRS - Université de Reims Champagne-Ardenne, B.P. 1039, 51687 Reims Cedex 2, France. jacques.muzart@univ-reims.fr.
Jean
J
Le Bras
Jacques
J
Muzart