[The proinsulin level in the blood of children with type 1 diabetes mellitus of various duration].
Proinsulin content was measured in the serum of 82 children (aged from 3 to 14 years) with type 1 diabetes mellitus of various duration. Three groups of patients characterized by low (54%), normal (42%) and high (4%) levels of this prohormone were recognized. No dependence the proinsulin level on the disease term was found. The serum proinsulin level may be used as a parameter specifying the pathogenesis of type 1 diabetes mellitus.
N Iu
NIu
Lotosh
A A
AA
Selishcheva
S A
SA
Nadorov
B A
BA
Badyshtov
I É
IÉ
Volkov
S V
SV
Savel'ev
D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D011384:Proinsulin / Q000097:blood*; D013997:Time Factors
D015415:Biomarkers; D011384:Proinsulin