High-resolution electron microscopy and spectroscopy of ferritin in biocompatible graphene liquid cells and graphene sandwiches.
Atomic and electronic structures of hydrated ferritin are characterized using electron microscopy and spectroscopy through encapsulation in single layer graphene in a biocompatible manner. Graphene's ability to reduce radiation damage levels to hydrogen bond breakage is demonstrated. A reduction of iron valence from 3+ to 2+ is measured at nanometer-resolution in ferritin, showing initial stages of iron release by ferritin.
Department of Physics, University of Illinois at Chicago, Chicago, IL, 60607, USA.
Canhui
C
Wang
Qiao
Q
Qiao
Tolou
T
Shokuhfar
Robert F
RF
Klie
D001672:Biocompatible Materials / Q000737:chemistry* / Q000528:radiation effects; D004583:Electrons; D005293:Ferritins / Q000737:chemistry* / Q000528:radiation effects; D006108:Graphite / Q000737:chemistry* / Q000528:radiation effects; D006860:Hydrogen Bonding; D017348:Microscopy, Electron, Scanning Transmission; D013057:Spectrum Analysis
D001672:Biocompatible Materials; D006108:Graphite; D005293:Ferritins
EELS; atomic resolution imaging; electron microscopy; ferritin; graphene liquid cell