When breast cancer cells start to fend the educational process of NK cells off.
The notion of natural killer (NK)-cell education has recently emerged, and accumulating evidence indicates that the terminal differentiation of NK cells can be achieved in the periphery. This means that the proper function of these lymphocytes is dependent on their environment, opening a new door through which cancer cells can escape immunosurveillance.
INSERM UMR1068; Marseille, France.
Emilie
E
Mamessier
INSERM UMR1068; Marseille, France.
Charlotte
C
Bourgin
INSERM UMR1068; Marseille, France.
Daniel
D
Olive
NK cells; TGFβ; anti-tumor immunity; breast cancer; education