Randomized clinical trial of therapeutic music video intervention for resilience outcomes in adolescents/young adults undergoing hematopoietic stem cell transplant: a report from the Children's Oncology Group.
BACKGROUND
To reduce the risk of adjustment problems associated with hematopoietic stem cell transplant (HSCT) for adolescents/young adults (AYAs), we examined efficacy of a therapeutic music video (TMV) intervention delivered during the acute phase of HSCT to: 1) increase protective factors of spiritual perspective, social integration, family environment, courageous coping, and hope-derived meaning; 2) decrease risk factors of illness-related distress and defensive coping; and 3) increase outcomes of self-transcendence and resilience.


METHODS
This was a multisite randomized, controlled trial (COG-ANUR0631) conducted at 8 Children's Oncology Group sites involving 113 AYAs aged 11-24 years undergoing myeloablative HSCT. Participants, randomized to the TMV or low-dose control (audiobooks) group, completed 6 sessions over 3 weeks with a board-certified music therapist. Variables were based on Haase's Resilience in Illness Model (RIM). Participants completed measures related to latent variables of illness-related distress, social integration, spiritual perspective, family environment, coping, hope-derived meaning, and resilience at baseline (T1), postintervention (T2), and 100 days posttransplant (T3).


RESULTS
At T2, the TMV group reported significantly better courageous coping (Effect Size [ES], 0.505; P = .030). At T3, the TMV group reported significantly better social integration (ES, 0.543; P = .028) and family environment (ES, 0.663; P = .008), as well as moderate nonsignificant effect sizes for spiritual perspective (ES, 0.450; P = .071) and self-transcendence (ES, 0.424; P = .088).


CONCLUSIONS
The TMV intervention improves positive health outcomes of courageous coping, social integration, and family environment during a high-risk cancer treatment. We recommend the TMV be examined in a broader population of AYAs with high-risk cancers.
Indiana University School of Nursing, Indianapolis, Indiana.
Sheri L
SL
Robb
Debra S
DS
Burns
Kristin A
KA
Stegenga
Paul R
PR
Haut
Patrick O
PO
Monahan
Jane
J
Meza
Timothy E
TE
Stump
Brooke O
BO
Cherven
Sharron L
SL
Docherty
Verna L
VL
Hendricks-Ferguson
Eileen K
EK
Kintner
Ann E
AE
Haight
Donna A
DA
Wall
Joan E
JE
Haase
D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000517:prevention & control; D002648:Child; D005195:Family Relations; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000523:psychology*; D006412:Hematopoietic Stem Cells; D065026:Hope; D006801:Humans; D008297:Male; D009147:Music Therapy / Q000379:methods*; D055500:Resilience, Psychological; D012934:Social Isolation / Q000523:psychology; D012944:Social Support; D013315:Stress, Psychological / Q000517:prevention & control; D055815:Young Adult
adolescents; cancer; courageous coping; family relations; music; music therapy; resilience; self-transcendence; social environment; young adult