Choline prevents cardiac hypertrophy by inhibiting protein kinase C-δ dependent transient receptor potential canonical 6 channel.
Institute of Clinical Pharmacy, The Second Affiliated Hospital, Harbin Medical University, Harbin 150086, Heilongjiang Province, China.
Jiancui
J
Qi
Institute of Clinical Pharmacy, The Second Affiliated Hospital, Harbin Medical University, Harbin 150086, Heilongjiang Province, China.
Shanshan
S
Tian
Institute of Clinical Pharmacy, The Second Affiliated Hospital, Harbin Medical University, Harbin 150086, Heilongjiang Province, China.
Zhihua
Z
Zhang
Institute of Clinical Pharmacy, The Second Affiliated Hospital, Harbin Medical University, Harbin 150086, Heilongjiang Province, China.
Chuanqin
C
Zha
Department of Pharmacology, Harbin Medical University, Harbin, 150081, Heilongjiang Province, China.
Yong
Y
Zhang
Institute of Clinical Pharmacy, The Second Affiliated Hospital, Harbin Medical University, Harbin 150086, Heilongjiang Province, China; Key Laboratory of Drug Research, Harbin Medical University, Heilongjiang Higher Education Institutions, Harbin 150086, Heilongjiang Province, China.
Pengzhou
P
Hang
Institute of Clinical Pharmacy, The Second Affiliated Hospital, Harbin Medical University, Harbin 150086, Heilongjiang Province, China; Key Laboratory of Drug Research, Harbin Medical University, Heilongjiang Higher Education Institutions, Harbin 150086, Heilongjiang Province, China. Electronic address: dzm1956@126.com.
Zhimin
Z
Du
D000818:Animals; D006332:Cardiomegaly / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*; D002794:Choline / Q000494:pharmacology*; D006801:Humans; D009206:Myocardium / Q000378:metabolism* / Q000473:pathology; D051745:Protein Kinase C-delta / Q000037:antagonists & inhibitors / Q000378:metabolism*; D050052:TRPC Cation Channels / Q000037:antagonists & inhibitors / Q000378:metabolism*
D050052:TRPC Cation Channels; D051745:Protein Kinase C-delta; D002794:Choline
Cardiac hypertrophy; Choline; Protein kinase C-δ; Transient receptor potential canonical 6