Osteosarcoma of the cranial vault and skull base in pediatric patients.
Cranial osteosarcoma is very rare in children, rendering the development of optimal treatment algorithms challenging. The authors present 3 cases of pediatric cranial osteosarcoma: a primary calvarial tumor, a cranial metastasis, and a primary osteosarcoma of the cranial base. A review of the literature demonstrates significant variation in the management of cranial osteosarcomas and the outcome for patients with these tumors. This series and literature review is presented to improve the understanding of pediatric cranial osteosarcoma and to reinforce the importance of maximal resection in optimizing outcome.
Department of Neurosurgery, Baylor College of Medicine and Division of Pediatric Neurosurgery, Texas Children's Hospital;
Caroline
C
Hadley
Loyola V
LV
Gressot
Akash J
AJ
Patel
Lisa L
LL
Wang
Ricardo J
RJ
Flores
William E
WE
Whitehead
Thomas G
TG
Luerssen
Andrew
A
Jea
Robert J
RJ
Bollo
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D019635:Neurosurgical Procedures / Q000379:methods*; D012516:Osteosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000628:therapy; D012888:Skull Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*