Hydroa vacciniforme-like cutaneous T-cell lymphoma.
A 14-year-old Chinese girl had a 6-year history of recurrent lesions on her head, face, and limbs. Epstein-Barr virus (EBV)-IgM was positive. Histopathological findings revealed focal lymphocyte invasion in subcutaneous panniculus adiposus, mainly surrounding the blood vessels. Immunohistochemistry showed CD3+, CD4+, CD5+, CD8+, TIA-1+, GrB+, CD56-, and L26-. In situ hybridization staining for EBV-encoded small nonpolyadenylated RNA (EBER)-1 was positive. The patient showed significant improvement in clinical symptoms after being treated with acyclovir and IFN-α in this patient.
Department of Dermatology, Guangdong Medical College, Xiashan District, Zhanjiang, Guangdong Province 524001, China.
Jian-Qiang
JQ
Shi
Department of Dermatology, Guangdong Medical College, Xiashan District, Zhanjiang, Guangdong Province 524001, China.
Qiu-Xia
QX
Chen
Department of Dermatology, Guangdong Medical College, Xiashan District, Zhanjiang, Guangdong Province 524001, China.
Shun-Fan
SF
Li
Department of Dermatology, Guangdong Medical College, Xiashan District, Zhanjiang, Guangdong Province 524001, China.
Wen
W
Li
Epstein-Barr virus; T-cell; hydroa vacciniforme-like; lymlphoma