[Clinic characteristics of patients with trophoblastic gestational disease complicate with hypertension].
BACKGROUND
The molar pregnancy is complicated with hypertension before 20 weeks, divided into complete mole and partial mole, and in diploid and triploid hydatidiform mola depending on the fetal chromosomes.


OBJECTIVE
To determine clinical and laboratory characteristics of patients with hydatidiform mole with and without hypertension, and choriocarcinoma, correlate serum chorionic gonadotropin (hCG) and hypertension.


METHODS
We reviewed 55 cases with histopathologically proven mole, separately analyzed clinical, laboratory and hCG.


RESULTS
The prevalence of mole with hypertension was 1:7; with the choriocarcinoma is 1:11. The age and sexual initiation of mole with hypertension was higher (p = .004 and .002 respectively), liver transaminase AST (p =. 004) and lactate dehydrogenase are higher in the group with hypertension (p =. 000). Positive correlation was obtained r = .246 p =. 044 statistically significant between mean arterial pressure and hCG. We reviewed 31 cases of 28 national and international articles, in patients with diploid hydatidiform the product is allowed to live normal and high blood pressure is showing mild preeclampsia, while partial moles are triploid, malformed products, incompatible with life and with hypertension severe like severe pre-eclampsia.


CONCLUSIONS
The molar pregnancy is partially diagnosed with hypertension in our environment, is not properly analyzed and that most of the products of curettage were not performed genetic testing. The hCG probably participate in the hypertensive disorders of pregnancy.
Hospital Juárez de México, SS, México, DF. asesortextosmedicos@gmail.com
José María
JM
Tovar-Rodríguez
Servicio de Ginecología y Obstetricia, Hospital Juárez de México, SS, México, DF.
Irais del Carmen
Idel C
Medel-Lagunes
Hospital Juárez de México, SS, México, DF.
Gustavo
G
Acosta-Altamirano
Hospital Juárez de México, SS, México, DF.
Víctor Manuel
VM
Vargas-Hernández
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001219:Aspartate Aminotransferases / Q000378:metabolism; D001794:Blood Pressure; D002822:Choriocarcinoma / Q000473:pathology*; D006063:Chorionic Gonadotropin / Q000097:blood; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000473:pathology*; D006973:Hypertension / Q000150:complications* / Q000453:epidemiology; D046110:Hypertension, Pregnancy-Induced / Q000453:epidemiology; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D011225:Pre-Eclampsia / Q000453:epidemiology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D012720:Severity of Illness Index; D014594:Uterine Neoplasms / Q000150:complications / Q000473:pathology*; D055815:Young Adult
D006063:Chorionic Gonadotropin; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases