Mycoplasma genitalium: clinical significance and diagnosis.
Mycoplasma genitalium is considered the smallest self-replicating cell. It was first isolated in 1981, from 2 of 13 men with urethritis. Mycoplasma genitalium causes urethritis, cervicitis and pelvic inflammatory disease. Because of difficulties in cultivation, the diagnosis is based exclusively on PCR methodology. The recommended therapy for Mycoplasma genitalium infections is azithromycin or doxycycline. Development of macrolide resistance was shown to correlate with treatment failure.
Assist. Prof. Vanda Plečko, MD, PhD, Department of Clinical and Molecular Microbiology, University Hospital Center Zagreb, Kišpatićeva 12, HR-10000 Zagreb, Croatia; vplecko@gmail.com.
Vanda
V
Plečko
Lidija
L
Zele Starčević
Vesna
V
Tripković
Violeta
V
Rezo Vranješ
Mihael
M
Skerlev
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017963:Azithromycin / Q000627:therapeutic use; D004318:Doxycycline / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D009175:Mycoplasma Infections / Q000175:diagnosis* / Q000188:drug therapy; D045704:Mycoplasma genitalium; D014526:Urethritis / Q000382:microbiology; D002575:Uterine Cervicitis / Q000382:microbiology
D000900:Anti-Bacterial Agents; D017963:Azithromycin; D004318:Doxycycline