Mini-nutritional assessment (MNA) is useful for assessing the nutritional status of patients with chronic obstructive pulmonary disease: a cross-sectional study.
Malnutrition is prevalent in patients with chronic obstructive pulmonary disease (COPD) but is often neglected in clinical practice. This study examined the usefulness of the Mini Nutritional Assessment (MNA) for assessing the nutritional status of patients with COPD. We recruited 83 patients with COPD in stable condition from the pulmonary rehabilitation unit of a medical center in northern Taiwan. Each patient was interviewed with a structured questionnaire to elicit personal and health-related data, and measured for anthropometric and blood biochemical indicators. Nutritional status was rated with two Taiwanese-specific versions of the MNA, MNA-T1 and MNA-T2. Fat-free mass was measured with bioelectrical impedance analysis (BIA), and exercise capacity indicators with the 6-Minute Walk Test. The two MNA versions showed high agreement (kappa = 0.949) in predicting the nutritional risk, and both versions predicted the FFMI well (area under the curve of the Receiver Operating Characteristics = 0.804, p < 0.001 for MNA-T1; and 0.813, p < 0.001 for MNA-T2). MNA scores decreased with increasing disease severity and were highly correlated with FFMI, BMI, mid-arm circumference, calf circumference, and oxygen saturation at rest and during exercise (all p < 0.01). The MNA score was positively correlated with FEV1, FVC and 6-minute walking distance, and negatively correlated with GOLD stages (all p < 0.05). However, the MNA score was not significantly correlated with blood biochemical indicators, perhaps due to inflammatory status associated with COPD. The MNA appears appropriate for rating the nutritional risk of patients with COPD. Routine use of the MNA may help reduce the risk of malnutrition in patients with COPD.
1Department of Healthcare Administration, Asia University , Wufeng, Taichung , Taiwan.
Min-Fang
MF
Hsu
Shu-Chuan
SC
Ho
Han-Pin
HP
Kuo
Jiun-Yi
JY
Wang
Alan C
AC
Tsai
D000368:Aged; D019540:Area Under Curve; D001132:Arm / Q000473:pathology; D001823:Body Composition; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D017097:Electric Impedance; D005080:Exercise Test; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000097:blood / Q000150:complications / Q000175:diagnosis; D008875:Middle Aged; D015596:Nutrition Assessment; D009752:Nutritional Status; D009924:Organ Culture Techniques; D010100:Oxygen / Q000097:blood; D029424:Pulmonary Disease, Chronic Obstructive / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D012372:ROC Curve; D011795:Surveys and Questionnaires; D013624:Taiwan
D010100:Oxygen
COPD; anthropometric; body composition; exercise capacity; mini nutritional assessment; nutritional status