[Cyanamide-ethanol reaction induced shock: report of a case and literature review].
Cyanamide is a known alcohol deterrent, and it may cause severe cyanamide-ethanol reaction if a patient consumes high amounts of alcohol during treatment. We report a rare case of cyanamide-ethanol reaction-induced shock in a 73-year-old man who was taking cyanamide for the treatment of alcohol dependence. The patient complained of acute onset of dyspnea after drinking. On arrival, he was in a state of shock. We immediately started hydration and administered 0.3 mg adrenaline by intramuscular injection. However, the patient's general condition did not improve. We could rescue him only after a high dose of adrenaline was administered by continuous intravascular injection. In general, in the treatment of cyanamide-ethanol reaction-induced shock, adrenaline or noradrenaline should be used instead of dopamine. Some cases of severe cyanamide-ethanol reactions have been recently reported in Japan. We performed a literature review and have discussed these cases in the text.
Department of Emergency Medicine, Graduate School of Medicine, University of the Ryukyus.
Yutaka
Y
Kondo
Department of Legal Medicine, Graduate School of Medicine, University of the Ryukyus.
Chiaki
C
Fuke
Department of Cardiovascular Medicine, Graduate School of Medicine, University of the Ryukyus.
Ayumi
A
Higa
Department of Emergency Medicine, Graduate School of Medicine, University of the Ryukyus.
Ichiro
I
Kukita
D000368:Aged; D000427:Alcohol Deterrents / Q000009:adverse effects*; D000428:Alcohol Drinking / Q000009:adverse effects*; D000434:Alcoholic Beverages / Q000009:adverse effects*; D000707:Anaphylaxis / Q000188:drug therapy* / Q000209:etiology*; D003484:Cyanamide / Q000009:adverse effects*; D004837:Epinephrine / Q000008:administration & dosage*; D000431:Ethanol / Q000009:adverse effects*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D012720:Severity of Illness Index; D016896:Treatment Outcome
D000427:Alcohol Deterrents; D000431:Ethanol; D003484:Cyanamide; D004837:Epinephrine