[One-year surveillance study of antimicrobial resistance in major bacteria except for MRSA isolated in eight medical facilities in Kumamoto prefecture].
To investigate the current status of drug-resistant bacteria (except MRSA) in Kumamoto prefecture, a study was conducted to determine the isolation numbers and ratios of extended-spectrum beta-lactamase (ESBL)-Escherichia coli, ESBL-Klebsiella species, ESBL-Proteus mirabilis, two-drug resistant Pseudomonas aeruginosa, (resistant to two drugs either carbapenems, quinolones and aminoglycosides) multi-drug-resistant Pseudomonas aeruginosa, multi-drug-resistant Acinetobacter baumannii, and vancomyacin-resistant Enterococcii in eight general hospitals from May in 2009 to April in 2010. ESBL-E. coli was mostly isolated, and two-drug resistant P. aeruginosa came second. The isolation ratio of overall drug-resistant bacteria did not increase, while the isolation ratio of two-drugs resistant P. aeruginosa declined, suggesting that infection control was successfully conducted in these hospitals. However, the isolation numbers of ESBL-Klebsiella spp. and two-drug resistant P. aeruginosa were variable in each hospital. Furthermore, drug-resistant bacteria were occasionally spread into another medical facilities by patients transferred from these hospitals, indicating that sharing information on drug-resistant bacteria between medical facilities is required.
The Chemo-Sero Therapeutic Research Institute.
Takayuki
T
Masaki
Department of Laboratory Medicine, Kumamoto University Hospital.
Masanori
M
Ohkuma
Tamana Central Hospital Clinical Laboratory.
Kuniaki
K
Nagata
Clinical Laboratory, Health Insurance Kumamoto General Hospital.
Mari
M
Kinoshita
Clinical Laboratory, Kumamoto Rosai Hospital.
Mikoto
M
Moriguchi
Clinical Laboratory, Amakusa Medical Center.
Masahiro
M
Isozaki
Kumamoto University, Faculty of Life Sciences.
Hitomi
H
Maeda
D024881:Drug Resistance, Bacterial; D018432:Drug Resistance, Multiple; D062665:Epidemiological Monitoring; D006769:Hospitals, General; D007564:Japan