Pulmonary arteriovenous malformations presenting as platypnea-orthodeoxia in graft-versus-host disease.
This case highlights the utility of agitated saline studies during transesophageal echocardiography (TEE) for detection of pulmonary arteriovenous malformations (PAVM) as a viable alternative to contrast-enhanced imaging studies. By carefully studying each pulmonary vein individually during saline contrast studies, TEE is able to demonstrate and localize PAVM. In addition, this report represents the first documentation of PAVM arising as a complication of graft-versus-host disease after allogeneic hematopoietic stem cell transplant.
Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
Mark
M
Anderson
Siddharth
S
Wayangankar
George
G
Selby
Chittur A
CA
Sivaram
D001165:Arteriovenous Malformations / Q000150:complications / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D017548:Echocardiography, Transesophageal / Q000379:methods*; D006086:Graft vs Host Disease / Q000150:complications / Q000000981:diagnostic imaging*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D000860:Hypoxia / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000002:abnormalities* / Q000000981:diagnostic imaging; D011667:Pulmonary Veins / Q000002:abnormalities* / Q000000981:diagnostic imaging