Guillain-barré syndrome in pregnancy: an unusual case.
Guillain-Barré syndrome (GBS) is rare in pregnancy with an estimated incidence between 1.2 and 1.9 cases per 100,000 people annually, and it carries a high maternal risk. We report a 29-year-old primigravida who had pain and progressive heaviness of both lower limbs in her third trimester of pregnancy. The attending gynecologist ascribed these symptoms to ongoing pregnancy. The intrapartum period (lower segment caesarian section) passed uneventfully. On third postpartum day, the patient developed weakness of all the four limbs. A detailed history and physical examination pointed toward GBS although there was no antecedent infective episode. Subsequent nerve conduction velocity studies and cerebrospinal fluid analysis confirmed GBS. All other investigations including electrolytes were normal. The patient improved without the introduction of immunomodulating therapy.
Department of Internal Medicine, SKIMS Medical College, Srinagar, Jammu and Kashmir, India.
Mir Sadaqat Hassan
MS
Zafar
Department of Internal Medicine, SKIMS Medical College, Srinagar, Jammu and Kashmir, India.
M Mubarik
MM
Naqash
Department of Internal Medicine, SKIMS Medical College, Srinagar, Jammu and Kashmir, India.
Tariq A
TA
Bhat
Department of Internal Medicine, SKIMS Medical College, Srinagar, Jammu and Kashmir, India.
G M
GM
Malik
GBS; immunomodulating therapy; post-partum period; pregnancy