A case of EBV positive diffuse large B-cell lymphoma of the adolescent.
EBV positive diffuse large B-cell lymphoma (DLBCL) can happen to the elderly, seldom to the young. The case of EBV positive DLBCL has rarely been reported in the adolescent. We report a rare case of EBV positive DLBCL in a 17-year-old man with normal immune state. He was diagnosed by morphology, immunohistochemistry, in situ hybridization for EBV, Flow cytometer, IG/TCR gene rearrangement and cytogenetic study. The occurrence of this case suggests that EBV-positive DLBCL can happen to adolescent patients with normal immune state and cytogenetic study takes an important role in the diagnosis of adolescent EBV-positive DLBCL.
Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Da Dao, Wuhan 430030, P. R. China.
Qilin
Q
Ao
Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Da Dao, Wuhan 430030, P. R. China.
Ying
Y
Wang
Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Da Dao, Wuhan 430030, P. R. China.
Sanpeng
S
Xu
Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Da Dao, Wuhan 430030, P. R. China.
Ye
Y
Tian
Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Da Dao, Wuhan 430030, P. R. China.
Wei
W
Huang
Diffuse large B-cell lymphoma; EBV; the adolescent