Biology and proteomics of extracellular vesicles: harnessing their clinical potential.
Extracellular membrane vesicles have recently emerged as versatile mediators of intercellular communication, pathogenesis, drug and gene delivery and as potentially rich reservoirs of clinical biomarkers. Channeling their properties toward patient care is dependent on technological progress in approaches used for their analysis and molecular profiling.
Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Crislyn
C
D'Souza-Schorey
Dolores
D
Di Vizio
D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D002450:Cell Communication; D055252:Cell-Derived Microparticles / Q000378:metabolism*; D055354:Exosomes / Q000378:metabolism; D006801:Humans; D007167:Immunotherapy; D009369:Neoplasms / Q000276:immunology / Q000378:metabolism / Q000628:therapy; D057285:Precision Medicine; D020543:Proteome / Q000378:metabolism
D015415:Biomarkers; D020543:Proteome
disease biomarkers; exosomes; microvesicles