Recurrent melioidosis in the Darwin Prospective Melioidosis Study: improving therapies mean that relapse cases are now rare.
The Darwin Prospective Melioidosis Study has documented 785 melioidosis cases over 23 years. Recurrent melioidosis occurred in 39/679 (5.7%) patients surviving initial infection; 29 patients suffered relapse of the original infection, and 10 presented with a new Burkholderia pseudomallei infection. With improved therapy, relapse has become rare in recent years.
Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
Derek S
DS
Sarovich
Linda
L
Ward
Erin P
EP
Price
Mark
M
Mayo
Matthew C
MC
Pitman
Robert W
RW
Baird
Bart J
BJ
Currie
D016957:Burkholderia pseudomallei / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D008554:Melioidosis / Q000188:drug therapy* / Q000453:epidemiology*; D011446:Prospective Studies; D055502:Secondary Prevention