An expanding world of small RNAs.
In ciliated protozoans, small RNAs (sRNAs) are integral to guiding large-scale genomic rearrangements after mating. Sandoval et al. (2014) report in this issue of Developmental Cell the discovery of a class of Paramecium sRNAs, produced by a unique Dicer-like enzyme, that likely provides late stage quality control in this process.
Department of Molecular, Cell and Developmental Biology and The Center for Molecular Biology of RNA, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Zachary T
ZT
Neeb
Department of Molecular, Cell and Developmental Biology and The Center for Molecular Biology of RNA, University of California, Santa Cruz, Santa Cruz, CA 95064, USA. Electronic address: zahler@ucsc.edu.
Alan M
AM
Zahler
D018503:Genome, Protozoan; D016805:Paramecium tetraurelia / Q000235:genetics*; D016053:RNA, Protozoan / Q000235:genetics*; D058727:RNA, Small Untranslated / Q000235:genetics*; D043244:Ribonuclease III / Q000235:genetics*
D016053:RNA, Protozoan; D058727:RNA, Small Untranslated; D043244:Ribonuclease III