Lensfree On-Chip Microscopy and Tomography for Bio-Medical Applications.
Lensfree on-chip holographic microscopy is an emerging technique that offers imaging of biological specimens over a large field-of-view without using any lenses or bulky optical components. Lending itself to a compact, cost-effective and mechanically robust architecture, lensfree on-chip holographic microscopy can offer an alternative toolset addressing some of the emerging needs of microscopic analysis and diagnostics in low-resource settings, especially for telemedicine applications. In this review, we summarize the latest achievements in lensfree optical microscopy based on partially coherent on-chip holography, including portable telemedicine microscopy, cell-phone based microscopy and field-portable optical tomographic microscopy. We also discuss some of the future directions for telemedicine microscopy and its prospects to help combat various global health challenges.
Electrical Engineering Department at the University of California, Los Angeles, CA 90095, USA.
Serhan O
SO
Isikman
Electrical Engineering Department at the University of California, Los Angeles, CA 90095, USA.
Waheb
W
Bishara
Electrical Engineering Department at the University of California, Los Angeles, CA 90095, USA.
Onur
O
Mudanyali
Electrical Engineering Department at the University of California, Los Angeles, CA 90095, USA.
Ikbal
I
Sencan
Electrical Engineering Department at the University of California, Los Angeles, CA 90095, USA.
Ting-Wei
TW
Su
Electrical Engineering Department at the University of California, Los Angeles, CA 90095, USA.
Derek
D
Tseng
Electrical Engineering Department at the University of California, Los Angeles, CA 90095, USA.
Oguzhan
O
Yaglidere
Electrical Engineering Department at the University of California, Los Angeles, CA 90095, USA.
Uzair
U
Sikora
Electrical Engineering Department at the University of California, Los Angeles, CA 90095, USA ( http://innovate.ee.ucla.edu/ ). California NanoSystems Institute (CNSI), at the University of California, Los Angeles, CA 90095, USA.
Aydogan
A
Ozcan
cell-phone microscopy; global health; holographic pixel super-resolution; lensfree imaging; lensfree tomography; lensless on-chip imaging; telemedicine microscopy