title: Influenza A virus lures autophagic protein LC3 to budding sites.
abstract: Autophagy, a cellular degradation pathway, can restrict or assist viral replication. In this issue of Cell Host & Microbe, Beale et al. (2014) report that the influenza virus matrix protein 2 binds to the essential autophagy protein LC3 to presumably transport LC3-conjugated membranes to the cell surface for budding of stable viruses.
authors: Viral Immunobiology, Institute of Experimental Immunology, University of Zürich, 8057 Zürich, Switzerland. Electronic address: christian.muenz@uzh.ch.
authors: Christian
authors: C
authors: Münz
mesh_terms: D001343:Autophagy; D054884:Host-Pathogen Interactions; D009980:Influenza A virus / Q000502:physiology*; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D054730:Protein Interaction Domains and Motifs; D014763:Viral Matrix Proteins / Q000378:metabolism*; D014771:Virion / Q000502:physiology*; D000086082:Viroporin Proteins
chemical_list: D008869:Microtubule-Associated Proteins; D014763:Viral Matrix Proteins; C488937:M2 protein, Influenza A virus; D000086082:Viroporin Proteins; C477012:MAP1LC3A protein, human