title: Accelerating parameter mapping with a locally low rank constraint.
abstract: OBJECTIVE
  To accelerate MR parameter mapping using a locally low rank (LLR) constraint, and the combination of parallel imaging and the LLR constraint.
  
  
  METHODS
  An LLR method is developed for MR parameter mapping and compared with a globally low rank method in a multiecho spin-echo T2 mapping experiment. For acquisition with coil arrays, a combined LLR and parallel imaging method is proposed. The proposed method is evaluated in a variable flip angle T1 mapping experiment and compared with the LLR method and parallel imaging alone.
  
  
  RESULTS
  In the multiecho spin-echo T2 mapping experiment, the LLR method is more accurate than the globally low rank method for acceleration factors 2 and 3, especially for tissues with high T2 values. Variable flip angle T1 mapping is achieved by acquiring datasets with 10 flip angles, each dataset accelerated by a factor of 6, and reconstructed by the proposed method with a small normalized root mean square error of 0.025.
  
  
  CONCLUSIONS
  The LLR method is likely superior to the globally low rank method for MR parameter mapping. The proposed combined LLR and parallel imaging method has better performance than the two methods alone, especially with highly accelerated acquisition.
authors: Department of Electrical Engineering, Magnetic Resonance Systems Research Laboratory, Stanford University, Stanford, California, USA.
authors: Tao
authors: T
authors: Zhang
authors: John M
authors: JM
authors: Pauly
authors: Ives R
authors: IR
authors: Levesque
mesh_terms: D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology*; D017352:Echo-Planar Imaging / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
keywords: compressed sensing; low rank; parallel imaging; parameter mapping; quantitative MRI