title: Diels-Alder construction of regiodifferentiated meta-amino phenols and derivatives.
abstract: Synthetic access to regiodifferentiated meta-amino phenols is described. The strategy relies upon distinct deprotonation conditions to afford regioisomeric thermodynamic and kinetic dienes that undergo a tandem Diels-Alder and retro-Diels-Alder sequence with assorted acetylenic dienophiles to afford a range of aromatic products.
authors: Department of Chemistry and Biochemistry, University of California , Santa Barbara, California 93106-9510, United States.
authors: Marisa G
authors: MG
authors: Weaver
authors: Wen-Ju
authors: WJ
authors: Bai
authors: Stephen K
authors: SK
authors: Jackson
authors: Thomas R R
authors: TR
authors: Pettus
mesh_terms: D020650:Combinatorial Chemistry Techniques; D007700:Kinetics; D008958:Models, Molecular; D015394:Molecular Structure; D010636:Phenols / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013816:Thermodynamics
chemical_list: D010636:Phenols