title: Early post-acute stroke seizures: clinical profile and outcome in a Nigerian stroke unit.
abstract: OBJECTIVE
  To describe the basic clinico-demographic profile and outcome of Early Post-Acute Stroke Seizures (EPASS).
  
  
  METHODS
  Two-hundred and fifty one patients admitted within 24 h of onset of stroke symptoms into the stroke unit of a tertiary care hospital were followed up for convulsive seizure(s) within 7 days of admission and for disease outcome in 42 days. Stroke subtype was defined by cranial computed tomography and ictal phenomenon was as described by the stroke unit doctors. Stroke severity was by the Canadian Neurological Scale (CNS) and Glasgow Coma Scale (GCS). Seizures were characterized as partial, generalized, or status. Stroke outcome was defined as discharge from inpatient care to follow-up or still in care and all cause in-hospital death. Data was compared between the group with and without seizures. The effect of age, sex, blood sugar, GCS, CNS, and seizure type on stroke outcome and time to in-hospital death in EPASS was tested on logistic regression and Cox proportional hazard regression.
  
  
  RESULTS
  EPASS occurred in 9.96% of subjects and intracerebral infarct was more associated with EPASS, a finding different from what is dominant in western literature.
  
  
  CONCLUSIONS
  Profile of EPASS may appear different in terms of stroke subtype in Sub-Saharan African populations. Larger prospective studies may clarify the position better.
authors: Department of Medicine, University of Benin Teaching Hospital, Benin City, Nigeria.
authors: Imarhiagbe Frank
authors: IF
authors: Aiwansoba
authors: Ordia Wallace
authors: OW
authors: Chukwuyem
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D004569:Electroencephalography; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D016016:Proportional Hazards Models; D011446:Prospective Studies; D012307:Risk Factors; D012640:Seizures / Q000150:complications / Q000453:epidemiology / Q000209:etiology*; D012720:Severity of Illness Index; D012959:Socioeconomic Factors; D020521:Stroke / Q000150:complications* / Q000453:epidemiology; D013997:Time Factors; D016896:Treatment Outcome