title: [Analysis of clinical features of traditional Chinese medicine symptoms and syndromes of 220 patients with chronic aplastic anemia].
abstract: OBJECTIVE
  To study Chinese medicine (CM) syndrome types of chronic aplastic anemia (CAA) patients and the distribution laws of typical CM symptoms in different genders.
  
  
  METHODS
  From June 2002 to June 2012, 220 CAA outpatients/inpatients at Department of Hematology, Zhejiang Chinese Medical Hospital were recruited. Patients' symptoms and signs, as well as four diagnostic information at the first onset were collected. CM syndrome differentiation was performed. The syndrome types and typical symptoms were analyzed.
  
  
  RESULTS
  (1) In the 220 CAA patients, there were 121 cases of Shen yang deficiency syndrome (55.0%), 18 of Shen yin deficiency syndrome type (8.18%), 81 cases of Shen yin-yang deficiency syndrome (36.82%). (2) The distribution of typical symptoms: fatigue and shortness of breath (77.12% males and 73.53% females), pale complexion (64.41% males and 57.84% females), low temperature of four limbs (12.71% males and 26.47% females), spontaneous perspiration and night sweating (32.20% males and 26.47% females), dry mouth and throat (6.78% males and 6.86% females), feverish feelings in palms and soles (14.41% males and 20.59% females), loose stool (6.78% males and 2.94% females), petechiae and ecchymosis (42.37% males and 43.14% females).
  
  
  CONCLUSIONS
  Shen yang deficiency syndrome was most often seen in CAA patients at the initial diagnosis, followed by Shen yin-yang deficiency syndrome. Shen yin deficiency syndrome was the least seen. In CM symptoms, fatigue and shortness of breath were most common seen, followed by pale complexion, skin petechia and ecchymosis.
authors: Department of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310006, China.
authors: Zhi
authors: Z
authors: Chen
authors: Department of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310006, China.
authors: Sheng-Yun
authors: SY
authors: Lin
authors: Department of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310006, China.
authors: Yu-Hong
authors: YH
authors: Zhou
authors: Department of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310006, China.
authors: Li-Qiang
authors: LQ
authors: Wu
authors: Center for Clinical Assessment and Analysis, First Clinical College of Zhejiang Chinese Medical University, Hangzhou 310006, China.
authors: Ying
authors: Y
authors: Zhang
authors: Department of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310006, China.
authors: Yi-Ping
authors: YP
authors: Shen
authors: Department of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310006, China.
authors: Zhi-Yin
authors: ZY
authors: Zheng
authors: Department of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310006, China.
authors: Jun-Fa
authors: JF
authors: Chen
authors: Department of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310006, China.
authors: Ying-Ying
authors: YY
authors: Shen
authors: Department of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310006, China.
authors: Ying-Ying
authors: YY
authors: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000741:Anemia, Aplastic / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods*; D008875:Middle Aged; D016711:Yang Deficiency / Q000175:diagnosis; D016710:Yin Deficiency / Q000175:diagnosis; D055815:Young Adult