title: Ethmoidal encephalocele associated with cerebrospinal fluid fistula: indications and results of mini-invasive transnasal approach.
abstract: Anterior skull base defects with encephalocele in adults are quite rare and can be a cause of spontaneous rhinoliquorrhea; however, cerebrospinal fluid (CSF) fistula can be not rarely misdiagnosed for several months or years. Five adult patients affected by ethmoidal encephalocele with CSF fistula were treated in our institute from 2006 through to 2011. Onset of clinical history was represented by rhinoliquorrhea, which was precociously recognized in only 1 patient; in the other 4, it was misdiagnosed for a period ranging from 11 months to 5 years. After clinical diagnosis of CSF fistula and after brain magnetic resonance imaging, ethmoidal encephalocele was evident in all patients; preoperative study was completed by spiral computed tomography scan, to clearly identify the skull base bone defect. All patients were operated on by transsphenoidal endonasal endoscope-assisted microsurgical approach through 1 nostril. The herniated brain was coagulated and removed, and reconstruction of cranial base was performed. Postoperative rhinoliquorrhea or other complications did not occur in any patient at short and late follow-up. All patients were discharged after a few days. Endonasal endoscope-assisted microsurgical approach was effective in exposing and repairing the ethmoidal bone defect; tridimensional vision and wide lateral and superior exposition of the operative field were possible in each patient, thanks to the use of microscope and angulated endoscope.
authors: From the *Department of Neurosciences, Neurosurgery, University of Rome Tor Vergata; and †Department of Diagnostic for Imaging, CIRAD Villa Benedetta of Rome, Rome, Italy.
authors: Mario Francesco
authors: MF
authors: Fraioli
authors: Giuseppe Emanuele
authors: GE
authors: Umana
authors: Giulia
authors: G
authors: Fiorucci
authors: Chiara
authors: C
authors: Fraioli
mesh_terms: D020341:Absorbable Implants; D000328:Adult; D000368:Aged; D002559:Cerebrospinal Fluid Rhinorrhea / Q000175:diagnosis* / Q000601:surgery; D003951:Diagnostic Errors; D004677:Encephalocele / Q000175:diagnosis* / Q000601:surgery; D005004:Ethmoid Bone / Q000002:abnormalities* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008866:Microsurgery / Q000379:methods; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D009296:Nasal Cavity / Q000601:surgery; D010168:Palmitates / Q000627:therapeutic use; D019651:Plastic Surgery Procedures / Q000379:methods; D019291:Skull Base / Q000002:abnormalities / Q000601:surgery; D014014:Tissue Adhesives / Q000627:therapeutic use; D036542:Tomography, Spiral Computed / Q000379:methods; D014885:Waxes / Q000627:therapeutic use
chemical_list: D006490:Hemostatics; D010168:Palmitates; D014014:Tissue Adhesives; D014885:Waxes; C055480:bone wax