title: Combined arteriovenous thrombolytic infusion for refractory renal vein thrombosis.
abstract: Acute renal vein thrombosis can rapidly lead to significant impairment and eventual loss of renal function. Classically presenting with flank pain, hematuria, and laboratory markers consistent with acute kidney injury, therapeutic anticoagulation is the mainstay of treatment. However, endovascular surgery offers a safe and effective alternative for renal salvage in the setting of acute renal vein thrombosis. Described is the use of combined arteriovenous thrombolytic infusion for refractory renal vein thromboses to quickly and effectively decrease clot burden in the micro- and macrovenous circulations while limiting systemic exposure.
authors: San Antonio Military Medical Center, San Antonio, TX. Electronic address: heafnert@gmail.com.
authors: Thomas A
authors: TA
authors: Heafner
authors: San Antonio Military Medical Center, San Antonio, TX.
authors: Daniel
authors: D
authors: Scott
authors: San Antonio Military Medical Center, San Antonio, TX.
authors: J Devin
authors: JD
authors: Watson
authors: San Antonio Military Medical Center, San Antonio, TX.
authors: Brandon
authors: B
authors: Propper
authors: Multicare Health System, Tacoma, WA.
authors: Chatt
authors: C
authors: Johnson
authors: San Antonio Military Medical Center, San Antonio, TX.
authors: Zachary M
authors: ZM
authors: Arthurs
mesh_terms: D000208:Acute Disease; D000328:Adult; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D007261:Infusions, Intra-Arterial; D007262:Infusions, Intravenous; D010690:Phlebography / Q000379:methods; D012077:Renal Artery; D012082:Renal Veins / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000503:physiopathology; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator