title: High-intensity interval training induces a modest systemic inflammatory response in active, young men.
abstract: 1) the extent to which an acute session of high-intensity interval training (HIIT) increases systemic inflammatory cytokines and chemokines, and 2) whether 2 weeks of HIIT training alters the inflammatory response. Eight recreationally active males (aged 22±2 years) performed 2 weeks of HIIT on a cycle ergometer (six HIIT sessions at 8-12 intervals; 60-second intervals, 75-second active rest) at a power output equivalent to 100% of their predetermined peak oxygen uptake (VO2max). Serum samples were collected during the first and sixth HIIT sessions at rest and immediately, 15, 30, and 45 minutes post-exercise. An acute session of HIIT induced significant increases in interleukin (IL)-6, IL-8, IL-10, tumor necrosis factor-α, and monocyte chemotactic protein-1 compared with rest. The concentrations of interferon-γ, granulocyte macrophage-colony-stimulating factor, and IL-1β were unaltered with an acute session of HIIT Two weeks of training did not alter the inflammatory response to an acute bout of HIIT exercise. Maximal power achieved during a VO2max test significantly increased 4.6%, despite no improvements in VO2max after 2 weeks of HIIT. These data suggest that HIIT exercise induces a small inflammatory response in young, recreationally active men; however, 2 weeks of HIIT does not alter this response.
authors: Department of Health, Leisure, and Exercise Science, Appalachian State University, Boone, NC, USA.
authors: Kevin A
authors: KA
authors: Zwetsloot
authors: Department of Health, Leisure, and Exercise Science, Appalachian State University, Boone, NC, USA.
authors: Casey S
authors: CS
authors: John
authors: Department of Health, Leisure, and Exercise Science, Appalachian State University, Boone, NC, USA.
authors: Marcus M
authors: MM
authors: Lawrence
authors: Department of Health, Leisure, and Exercise Science, Appalachian State University, Boone, NC, USA.
authors: Rebecca A
authors: RA
authors: Battista
authors: Department of Health, Leisure, and Exercise Science, Appalachian State University, Boone, NC, USA ; Human Performance Laboratory, North Carolina Research Campus, Appalachian State University, Kannapolis, NC, USA.
authors: R Andrew
authors: RA
authors: Shanely
keywords: cycle ergometer; exercise training; inflammatory cytokines