title: Cancer drugs inhibit morphogenesis in the human fungal pathogen, Candida albicans.
abstract: Candida infections are very common in cancer patients and it is a common practice to prescribe antifungal antibiotics along with anticancer drugs. Yeast to hyphal form switching is considered to be important in invasive candidiasis. Targeting morphogenetic switching may be useful against invasive candidiasis. In this study, we report the antimorphogenetic properties of thirty cancer drugs.
authors: DST-FIST and UGC-SAP Sponsored School of Life Sciences, SRTM University, MS, India.
authors: Madhushree M
authors: MM
authors: Routh
authors: DST-FIST and UGC-SAP Sponsored School of Life Sciences, SRTM University, MS, India.
authors: Nitin M
authors: NM
authors: Chauhan
authors: DST-FIST and UGC-SAP Sponsored School of Life Sciences, SRTM University, MS, India.
authors: S Mohan
authors: SM
authors: Karuppayil
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000166:cytology / Q000187:drug effects* / Q000254:growth & development; D058492:Drug Repositioning; D006801:Humans; D025301:Hyphae / Q000166:cytology / Q000187:drug effects* / Q000254:growth & development; D008826:Microbial Sensitivity Tests; D008853:Microscopy
chemical_list: D000935:Antifungal Agents; D000970:Antineoplastic Agents
keywords: Candida albicans; antifungal antibiotics; cancer drugs; morphogenetic switching