title: CTAB functionalized graphene oxide/multiwalled carbon nanotube composite modified electrode for the simultaneous determination of ascorbic acid, dopamine, uric acid and nitrite.
abstract: We have developed hexadecyl trimethyl ammonium bromide (CTAB) functionalized graphene oxide (GO)/multiwalled carbon nanotubes (MWNTs) modified glassy carbon electrode (CTAB-GO/MWNT) as a novel system for the simultaneous determination of dopamine (DA), ascorbic acid (AA), uric acid (UA) and nitrite (NO2(-)). The combination of graphene oxide and MWNTs endow the biosensor with large surface area, good biological compatibility, electricity and stability, high selectivity and sensitivity. In the fourfold co-existence system, the linear calibration plots for AA, DA, UA and NO2(-) were obtained over the range of 5.0-300 μM, 5.0-500 μM, 3.0-60 μM and 5.0-800 μM with detection limits of 1.0 μM, 1.5 μM, 1.0 μM and 1.5 μM, respectively. In addition, the modified biosensor was applied to the determination of AA, DA, UA and NO2(-) in urine samples by using standard adding method with satisfactory results.
authors: School of Chemistry and Chemical Engineering, Xuchang University, Xuchang, Henan 461000, China. Electronic address: yangyujun@yahoo.com.
authors: Yu Jun
authors: YJ
authors: Yang
authors: University Library, Xuchang University, Xuchang, Henan 461000, China.
authors: Weikun
authors: W
authors: Li
mesh_terms: D001205:Ascorbic Acid / Q000652:urine*; D015374:Biosensing Techniques / Q000379:methods; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry*; D004298:Dopamine / Q000652:urine*; D055664:Electrochemical Techniques / Q000379:methods; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009573:Nitrites / Q000652:urine*; D010087:Oxides / Q000737:chemistry; D014527:Uric Acid / Q000652:urine*
chemical_list: D002593:Cetrimonium Compounds; D037742:Nanotubes, Carbon; D009573:Nitrites; D010087:Oxides; D014527:Uric Acid; D006108:Graphite; D001205:Ascorbic Acid; D004298:Dopamine; D000077286:Cetrimonium
keywords: Ascorbic acid; Biosensor; Dopamine; Graphene oxide; Nitrite; Uric acid