title: Does significant weight reduction in men with coronary artery disease manage risk factors after cardiac rehabilitation program?
abstract: BACKGROUND
  Vast majority of cardiac patients who refer to cardiac rehabilitation program (CRP) are obese and obesity is associated with coronary heart disease (CHD). So, the aim of this study is to investigate the effects of CRP on obesity indexes, lipid profiles, and functional capacity (FC) in obese men with CHD and to explore whether significant weight reduction affected these risk factors and FC or not.
  
  
  METHODS
  In an observational study, we evaluated 536 patients, including 464 non-obese men and 72 obese men. All participants completed CRP for 2 months; then, obese patients were divided into two groups: patients with weight reduction ≥ 5% and patients who didn't have significant weight reduction. Data were analyzed with SPSS software version 15. For comparing the mean of outcomes independent t-tests and paired t-tests were used.
  
  
  RESULTS
  Results showed following CRP, non-obese men had significant improvement in obesity indexes (P = 0.00), lipid profiles (P < 0.05), and FC (P = 0.00) and in obese men, favorable improvement were seen in obesity indexes (P = 0.00), FC (P = 0.00), and total cholesterol (P = 0.02). Comparing two groups revealed that there were significant differences in obesity indexes, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio. In addition, comparing subgroup of obese patients revealed that there were significant differences in FC (P = 0.00) and low-density lipoprotein cholesterol/ high-density lipoprotein cholesterol ratio (P = 0.04).
  
  
  CONCLUSIONS
  CRP has more advantage in management of obesity, FC, and lipid profiles in both obese and non-obese patients. Also, weight reduction may cause greater improvement in FC and fitness levels in obese men with CHD.
authors: Department of Cardiology, Cardiac Rehabilitation Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Masoumeh
authors: M
authors: Sadeghi
authors: Department of Physical Education and Sport Sciences, Khorasgan Branch, Islamic Azad University, Isfahan, Iran.
authors: Fatemeh Esteki
authors: FE
authors: Ghashghaei
authors: Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Katayoun
authors: K
authors: Rabiei
authors: Cardiac Electrophysiology Research Center, Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors: Allahyar
authors: A
authors: Golabchi
authors: Biostatics Unit, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Fatemeh
authors: F
authors: Noori
authors: Department of Internal Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
authors: Mozhgan Teimourzadeh
authors: MT
authors: Baboli
authors: Department of Cardiology, Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Nizal
authors: N
authors: Sarrafzadegan
keywords: Coronary artery disease; obesity; risk factor cardiac rehabilitation program; weight reduction