title: Hereditary spastic paraplegia type 5: a potentially treatable disorder of cholesterol metabolism.
authors: Unit of Neurology and Neurometabolic Disorders, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
authors: Andrea
authors: A
authors: Mignarri
authors: Alessandro
authors: A
authors: Malandrini
authors: Marina
authors: M
authors: Del Puppo
authors: Alessandro
authors: A
authors: Magni
authors: Lucia
authors: L
authors: Monti
authors: Federica
authors: F
authors: Ginanneschi
authors: Alessandra
authors: A
authors: Tessa
authors: Filippo Maria
authors: FM
authors: Santorelli
authors: Antonio
authors: A
authors: Federico
authors: Maria Teresa
authors: MT
authors: Dotti
mesh_terms: D000328:Adult; D000924:Anticholesteremic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D000072474:Cytochrome P450 Family 7; D005260:Female; D006801:Humans; D006888:Hydroxycholesterols / Q000097:blood*; D008297:Male; D009154:Mutation / Q000235:genetics; D019821:Simvastatin / Q000008:administration & dosage / Q000494:pharmacology*; D015419:Spastic Paraplegia, Hereditary / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy* / Q000235:genetics; D013250:Steroid Hydroxylases / Q000235:genetics; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000924:Anticholesteremic Agents; D006888:Hydroxycholesterols; C076996:27-hydroxycholesterol; D019821:Simvastatin; D013250:Steroid Hydroxylases; D000072474:Cytochrome P450 Family 7; C499571:CYP7B1 protein, human