title: Epitope mapping with membrane-bound synthetic overlapping peptides.
abstract: Epitope mapping with synthetic overlapping peptides is used for identifying epitopes of monoclonal antibodies (mAbs) and antibodies from patient sera (Midoro-Horiuti et al. Mol Immunol 43:509-518, 2006; Ivanciuc et al. J Agric Food Chem 51:4830-4837, 2003; Midoro-Horiuti et al. Mol Immunol 40:555-562, 2003; Wang et al. J Allergy Clin Immunol 125:695-702, 702.e1-702.e6, 2010). When the mAbs recognize epitopes that are also recognized by patients of interest, they may be useful as surrogates for patient antibodies.
authors: Department of Pediatrics, University of Texas Medical Branch, Galveston, TX, USA.
authors: Terumi
authors: T
authors: Midoro-Horiuti
authors: Randall M
authors: RM
authors: Goldblum
mesh_terms: D000911:Antibodies, Monoclonal / Q000276:immunology; D002462:Cell Membrane / Q000378:metabolism*; D018604:Epitope Mapping / Q000379:methods*; D000939:Epitopes / Q000276:immunology; D010455:Peptides / Q000276:immunology / Q000378:metabolism*
chemical_list: D000911:Antibodies, Monoclonal; D000939:Epitopes; D010455:Peptides