title: Recommendations on diagnosis and treatment of depression in patients with multiple sclerosis.
abstract: Multiple sclerosis (MS) is frequently associated with depression. Yet there are few clinical trials on treating depression in MS and no agreed recommendations for its assessment and follow-up. We present evidence-based recommendations for several aspects of depression in MS, including screening for depression, recognition of other concomitant psychiatric conditions, suicide risk, disability, fatigue, cognition, adherence to treatment, the effect of drugs used to treat MS on depression and possible pharmacological treatments for depression in MS.
authors: Department of Neurology, MS Reference Center, Universidade Metropolitana de Santos, Santos, SP, Brazil.
authors: Yara Dadalti
authors: YD
authors: Fragoso
authors: Department of Neurology, MS Reference Center, Hospital Sirio-Libanes, Sao Paulo, SP, Brazil.
authors: Tarso
authors: T
authors: Adoni
authors: Department of Neurology, MS Reference Center, Universidade Metropolitana de Santos, Santos, SP, Brazil.
authors: Andrea
authors: A
authors: Anacleto
authors: Department of Neurology, MS Reference Center, Pontificia Universidade Catolica de Sao Paulo, Campus Sorocaba, Sorocaba, SP, Brazil.
authors: Paulo Diniz
authors: PD
authors: da Gama
authors: Department of Neurology, MS Unit, Centro Hospitalar Unimed, Joinville, SC, Brazil.
authors: Marcus Vinicus Magno
authors: MV
authors: Goncalves
authors: Department of Neurology, MS Reference Center, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, RJ, Brazil.
authors: Andre Palma da Cunha
authors: AP
authors: Matta
authors: MS Reference Unit Curitiba, Neurology Clinic, Curitiba, PR, Brazil.
authors: Monica Fiuza Koncke
authors: MF
authors: Parolin
mesh_terms: D003071:Cognition; D003863:Depression / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D005221:Fatigue / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D009103:Multiple Sclerosis / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D018570:Risk Assessment; D000092864:Suicide Prevention
keywords: Depression; Multiple Sclerosis; Neuroimmunology