title: Injectable and tunable poly(ethylene glycol) analogue hydrogels based on poly(oligoethylene glycol methacrylate).
abstract: Injectable PEG-analogue hydrogels based on poly(oligoethylene glycol methacrylate) have been developed based on complementary hydrazide and aldehyde reactive linear polymer precursors. These hydrogels display the desired biological properties of PEG, form covalent networks in situ following injection, and are easily modulated for improved control over their functionality and physiochemical properties.
authors: Department of Chemical Engineering, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4L7. hoaretr@mcmaster.ca.
authors: Niels M B
authors: NM
authors: Smeets
authors: Emilia
authors: E
authors: Bakaic
authors: Mathew
authors: M
authors: Patenaude
authors: Todd
authors: T
authors: Hoare
mesh_terms: D016475:3T3 Cells; D000327:Adsorption; D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D005340:Fibrinogen / Q000737:chemistry; D006835:Hydrazones / Q000737:chemistry; D020100:Hydrogels / Q000008:administration & dosage / Q000737:chemistry* / Q000494:pharmacology; D007279:Injections, Subcutaneous; D008689:Methacrylates / Q000008:administration & dosage / Q000737:chemistry* / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C; D011092:Polyethylene Glycols / Q000008:administration & dosage / Q000737:chemistry* / Q000494:pharmacology; D011109:Polymethacrylic Acids; D012710:Serum Albumin, Bovine / Q000737:chemistry
chemical_list: D006835:Hydrazones; D020100:Hydrogels; D008689:Methacrylates; D011109:Polymethacrylic Acids; C528061:poly(poly(ethylene glycol)methacrylate); D012710:Serum Albumin, Bovine; D011092:Polyethylene Glycols; D005340:Fibrinogen