title: Food-dependent exercise-induced anaphylaxis with negative allergy testing.
abstract: Food-dependent exercise-induced anaphylaxis (FDEIA) is a disorder where exercise following allergen ingestion triggers anaphylaxis although exercise and allergen exposure are independently tolerated. The diagnosis of FDEIA is based on a characteristic clinical history. The culprit allergen is usually confirmed through the use of skin prick testing (SPT) serum-specific IgE levels and a food-exercise challenge. We present a case of FDEIA suggested by clinical history and open food-exercise challenge with negative specific IgE levels and SPT that highlights the challenges involved in diagnosing and managing this rare disorder.
authors: Department of Medicine, McGill University, Montreal, Canada.
authors: Jacob
authors: J
authors: Kleiman
authors: Moshe
authors: M
authors: Ben-Shoshan
mesh_terms: D000707:Anaphylaxis / Q000276:immunology*; D002648:Child; D015444:Exercise; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D010328:Patch Tests
chemical_list: D007073:Immunoglobulin E