title: Base mediated synthesis of 2-aryl-2,3-dihydroquinazolin-4(1H)-ones from 2-aminobenzonitriles and aromatic aldehydes in water.
abstract: An environmentally friendly and mild procedure to obtain 2,3-dihydroquinazolin-4(1H)-ones from 2-aminobenzonitriles and aromatic aldehydes has been developed. The reactions took place in water with inorganic base (K3PO4) as the only promoter. Various desired products have been prepared in moderate to good yields under identical conditions. Further transformation of dihydroquinazolinones to quinazolinones was carried out as well with TBHP as the oxidant.
authors: Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou, Zhejiang Province, People's Republic of China. xiao-feng.wu@catalysis.de.
authors: Xiao-Feng
authors: XF
authors: Wu
authors: Stefan
authors: S
authors: Oschatz
authors: Axel
authors: A
authors: Block
authors: Anke
authors: A
authors: Spannenberg
authors: Peter
authors: P
authors: Langer