title: In vitro maturation: Clinical applications.
abstract: Oocyte in vitro maturation (IVM) is an assisted reproductive technology in which oocytes are retrieved from the antral follicles of unstimulated or minimally stimulated ovaries. IVM of human oocytes has emerged as a promising procedure. This new technology has advantages over controlled ovarian stimulation such as reduction of costs, simplicity, and elimination of ovarian hyperstimulation syndrome. By elimination or reduction of gonadotropin stimulation, IVM offers eligible infertile couples a safe and convenient form of treatment, and IVM outcomes are currently comparable in safety and efficacy to those of conventional in vitro fertilization. IVM has been applied mainly in patients with polycystic ovary syndrome or ultrasound-only polycystic ovaries, but with time, the indications for IVM have expanded to other uncommon situations such as fertility preservation, as well as to normal responders. In this review, the current clinical experiences with IVM will be described.
authors: Maria Fertility Hospital, Seoul, Korea.
authors: Kyung Sil
authors: KS
authors: Lim
authors: Maria Fertility Hospital, Seoul, Korea.
authors: Soo Jin
authors: SJ
authors: Chae
authors: Maria Fertility Hospital, Seoul, Korea.
authors: Chang Woo
authors: CW
authors: Choo
authors: Maria Fertility Hospital, Seoul, Korea.
authors: Yeon Hee
authors: YH
authors: Ku
authors: Maria Fertility Hospital, Seoul, Korea.
authors: Hye Jun
authors: HJ
authors: Lee
authors: Maria Fertility Hospital, Seoul, Korea.
authors: Chang Young
authors: CY
authors: Hur
authors: Maria Fertility Hospital, Seoul, Korea.
authors: Jin Ho
authors: JH
authors: Lim
authors: Maria Fertility Hospital, Seoul, Korea.
authors: Won Don
authors: WD
authors: Lee
keywords: In vitro maturation; Infertility; Ovarian hyperstimulation syndrome