title: Prevalence of memory disorders in ambulatory patients aged ≥70 years with chronic heart failure (from the EFICARE study).
abstract: The aim of this multicenter observational study conducted in France was to determine the prevalence of memory impairment in ambulatory patients aged≥70 years with chronic heart failure (HF). Two hundred ninety-one cardiologists recruited 912 ambulatory patients with HF (mean age 79.2±5.8 years) from January to November 2009. Memory was evaluated by the delayed-recall Memory Impairment Screen (MIS-D). Memory impairment was defined as MIS-D score≤6 and severe memory impairment as MIS-D score≤4. HF was diagnosed 4.4±4.8 years earlier and mean left ventricular ejection fraction was 43.6±12.0%. Memory impairment was found in 416 subjects (45.6%, 95% confidence interval 42.4 to 48.8) and severe memory impairment in 213 subjects (23.4%, 95% confidence interval 20.6 to 26.1), whereas cardiologists only suspected memory impairment in 109 patients (12%; before evaluation by MIS). Determinants of memory disorders included older age, lower education level, depression, history of stroke, renal failure, and less regular physical activity. The severity of memory impairment increased with increasing severity of HF (New York Heart Association classification; p<0.00001). In conclusion, memory impairment in older patients with HF is common. The use of a simple-to-use tool such as the MIS-D may identify patients at risk and enable implementation of management strategies to improve therapeutic compliance.
authors: Service de Gérontologie, Hôpital Broca, Assistance Publique-Hôpitaux de Paris, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Equipe d'Accueil (EA) 4468, Paris, France. Electronic address: olivier.hanon@brc.aphp.fr.
authors: Olivier
authors: O
authors: Hanon
authors: Service de Gérontologie, Hôpital Broca, Assistance Publique-Hôpitaux de Paris, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Equipe d'Accueil (EA) 4468, Paris, France.
authors: Jean-Sébastien
authors: JS
authors: Vidal
authors: Service de Cardiologie, Centre Hospitalier Régional Universitaire de Lille, Lille, France.
authors: Pascal
authors: P
authors: de Groote
authors: Service de Cardiologie, Centre Hospitalier Universitaire de Rangueil, Toulouse, France.
authors: Michel
authors: M
authors: Galinier
authors: Service de Cardiologie, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France; Université Pierre et Marie Curie, Paris, France.
authors: Richard
authors: R
authors: Isnard
authors: Service de Cardiologie, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France; INSERM U942, Université Paris Diderot, Paris, France.
authors: Damien
authors: D
authors: Logeart
authors: Service de Cardiologie, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France; Université Pierre et Marie Curie, Paris, France.
authors: Michel
authors: M
authors: Komajda
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition / Q000502:physiology*; D005260:Female; D005602:France / Q000453:epidemiology; D006333:Heart Failure / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology; D010045:Outpatients; D015995:Prevalence; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D013318:Stroke Volume; D016277:Ventricular Function, Left