title: Antioxidant activity and total phenolic content of endophytic fungus Fennellia nivea NRRL 5504.
abstract: Antioxidant is an interesting bioactivity since it has several correlations with disease such as Alzheimer, cancer, ageing and many others in which were promoted by free radicals. Investigation on our endophytic fungus collection namely Fennelia nivea NRRL 5504 revealed that the fermented mediumhas antioxidant property against DPPH through free radical scavenging effect. Fermentation in liquid medium i.e. Potatoes Dextrose Broth, resulted that the fermented medium reached about 86.51% (p < 0.05) of free radical inhibition on the eighth day. Results ofphytochemical screening from extracted fermentation medium showed the presence of terpenes, triterpenes, phenolic compound, tannin, flavonoid and also saponin. The highest antioxidant activity was showed by ethyl acetate extract. Calculation on total phenolic content of ethyl acetate crude extract was 0.544 mg g(-1) equivalent to pyrogallol. By exposure above, we have alternative source of antioxidant that came from our endophytic fungus collection which we isolated previously from Typhonium divaricatum Lodd.
authors: Research Centre for Chemistry, Indonesian Institute of Sciences, Jl. Cisitu Sangkuriang Gd.50 Bandung, 40135, Indonesia.
authors: Vienna
authors: V
authors: Saraswaty
authors: Research Centre for Chemistry, Indonesian Institute of Sciences, Jl. Cisitu Sangkuriang Gd.50 Bandung, 40135, Indonesia.
authors: Yoice
authors: Y
authors: Srikandace
authors: Department of Chemistry, University of Jenderal Ahmad Yani, Jl. Terusan Jenderal Sudirman PO BOX 148, Cimahi, Indonesia.
authors: N A
authors: NA
authors: Simbiyani
authors: Department of Chemistry, University of Jenderal Ahmad Yani, Jl. Terusan Jenderal Sudirman PO BOX 148, Cimahi, Indonesia.
authors: Jasmansyah
authors: Analytical Chemistry Research Group, Faculty of Mathematic and Sciences, Institute of Technology Bandung, Jl. Ganesha 10. Bandung, Indonesia.
authors: Henry
authors: H
authors: Setiyanto
authors: Research Centre for Chemistry, Indonesian Institute of Sciences, Jl. Cisitu Sangkuriang Gd.50 Bandung, 40135, Indonesia.
authors: Zalinar
authors: Z
authors: Udin
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification; D001230:Aspergillus / Q000737:chemistry* / Q000145:classification; D001713:Biphenyl Compounds / Q000737:chemistry; D005285:Fermentation; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification; D010851:Picrates / Q000737:chemistry
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D010636:Phenols; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl