title: Multiple aseptic splenic abscesses in a 15 year old patient.
abstract: BACKGROUND
  Splenic abscesses in children are rare. In recent years aseptic abscesses have been recognized as a new disease entity, especially in adults.
  
  
  METHODS
  We present a rare case of a 15 year old girl with aseptic abscesses, in whom antibiotic therapy comprising metronidazole and meropenem was partly beneficial in improving the patient's clinical condition and inflammatory parameters. Eventually corticosteroid therapy led to complete and long lasting resolution of symptoms. Further diagnostic work-up revealed autoimmune thyroiditis, but no signs of inflammatory bowel disease.
  
  
  CONCLUSIONS
  Aseptic splenic abscesses should always prompt clinicians to initiate further diagnostics to determine a potential underlying condition and a regular follow-up. Anaerobic bacteria may play a role in the pathogenesis of the disease and besides corticosteroid treatment antibiotics covering anaerobes may be beneficial.
authors: Alexander J
authors: AJ
authors: Jordan
authors: Klaus-Peter
authors: KP
authors: Becker
authors: Metin
authors: M
authors: Sertemir
authors: K Wolfgang
authors: KW
authors: Neff
authors: Rüdiger
authors: R
authors: Adam
authors: Horst
authors: H
authors: Schroten
authors: Paediatric Infectious Diseases, Department of Paediatrics, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. tobias.tenenbaum@umm.de.
authors: Tobias
authors: T
authors: Tenenbaum
mesh_terms: D018784:Abdominal Abscess / Q000188:drug therapy* / Q000382:microbiology; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D011241:Prednisone / Q000627:therapeutic use*; D013158:Splenic Diseases / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D011241:Prednisone