title: A protective chaperone for the kinetochore adaptor Bub3.
abstract: In this issue of Developmental Cell, two complementary studies by Jiang et al. (2014) and Toledo et al. (2014) identify BuGZ as an interacting protein of the kinetochore adaptor Bub3 and show that it promotes the stabilization and kinetochore loading of Bub3, chromosome alignment, and mitotic progression.
authors: Howard Hughes Medical Institute, Department of Pharmacology, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390, USA.
authors: Zhejian
authors: Z
authors: Ji
authors: Howard Hughes Medical Institute, Department of Pharmacology, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390, USA. Electronic address: hongtao.yu@utsouthwestern.edu.
authors: Hongtao
authors: H
authors: Yu
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins / Q000737:chemistry*; D002877:Chromosomes, Human / Q000235:genetics*; D005909:Glioblastoma / Q000473:pathology*; D006801:Humans; D018386:Kinetochores / Q000378:metabolism*; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D008938:Mitosis / Q000502:physiology*; D000075223:Poly-ADP-Ribose Binding Proteins; D008941:Spindle Apparatus / Q000502:physiology*; D016335:Zinc Fingers / Q000235:genetics*
chemical_list: C489444:BUB3 protein, human; D018797:Cell Cycle Proteins; D008869:Microtubule-Associated Proteins; D000075223:Poly-ADP-Ribose Binding Proteins