title: Clinical presentation of human African trypanosomiasis in Zambia is linked to the existence of strains of Trypanosoma brucei rhodesiense with varied virulence: two case reports.
abstract: BACKGROUND
  Trypanosoma brucei rhodesiense typically causes acute and severe human African trypanosomiasis in Zambia and other countries in Eastern and Southern Africa. Although a few atypical cases of chronic and mild forms of this disease were reported in Zambia more than 40 years ago, no such cases have been diagnosed over the last four decades.
  
  
  METHODS
  For the first case, a 19-year-old Black African woman from the Eastern Province of Zambia presented with symptoms and signs of an atypical chronic and mild form of the disease for a period of 2 years. For the second case, a 16-year-old Black African boy from the Northern Province presented with symptoms and signs of a typical acute and severe form of the disease for 3 weeks.
  
  
  CONCLUSIONS
  Two strains of T. b. rhodesiense with varying degrees of virulence still do exist in Zambia. This has implications for control strategies at the national level.
authors: Copperbelt University, School of Medicine, Ndola, Zambia. vicsale@zamtel.zm.
authors: Victor
authors: V
authors: Mwanakasale
authors: Peter
authors: P
authors: Songolo
authors: Olusegun
authors: O
authors: Babaniyi
authors: Pere
authors: P
authors: Simarro