title: Low-toxic Ag2S quantum dots for photoelectrochemical detection glucose and cancer cells.
abstract: A new photoelectrochemical (PEC) biosensor was developed using low-toxic Ag2S QDs as photoelectrochemically active species. Energy levels of Ag2S and Ag2Se QD were compared to explain their differences in the PEC performance. The preparation condition of Ag2S QD was optimized and its structure characterization was measured. Then the developed photoelectric active interface was used to detect glucose and MCF-7 cancer cell and showed the good sensitivity and specificity. Under optimal condition, detection limits of 3.2 × 10(-5)M for glucose and 98 cells/mL for MCF-7 cell were achieved. Thus, the prepared Ag2S QD could serve as an excellent and promising photoelectric active material in the PEC biosensor.
authors: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.
authors: Xiaoru
authors: X
authors: Zhang
authors: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.
authors: Mingshuai
authors: M
authors: Liu
authors: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.
authors: Hongxia
authors: H
authors: Liu
authors: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China; Key Laboratory of Detection Technology of Shandong Province for Tumor Marker, College of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, PR China. Electronic address: shushzhang@126.com.
authors: Shusheng
authors: S
authors: Zhang
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D055664:Electrochemical Techniques / Q000379:methods; D005947:Glucose / Q000032:analysis*; D006801:Humans; D057230:Limit of Detection; D061986:MCF-7 Cells; D009369:Neoplasms / Q000737:chemistry*; D045663:Quantum Dots / Q000737:chemistry*; D018030:Silver Compounds / Q000737:chemistry*
chemical_list: D018030:Silver Compounds; C013251:silver sulfide; D005947:Glucose
keywords: Ag(2)S quantum dots; Cancer cell; Glucose; Photoelectrochemical biosensor