title: Severe systemic Bacillus anthracis infection in an intravenous drug user.
abstract: There has recently been an outbreak of injectional anthrax infection secondary to contaminated heroin use in the UK and Europe. We present a case of a 37-year-old man presenting with pain and swelling in the groin following injection of heroin into the area. He was initially treated for severe cellulitis, however, he failed to respond to appropriate antimicrobial therapy. He went onto develop a widespread rash; it was then that a diagnosis of injectional anthrax infection was considered. Appropriate investigations were initiated including serum sample and tissue biopsy, and the diagnosis was confirmed. Management included extensive surgical debridement and a prolonged course of combination antibiotic therapy. The authors summarise the important steps in diagnosis and the management options in patients presenting with this life-threatening infection.
authors: Countess of Chester NHS Foundation Trust, Chester, UK.
authors: Jessica
authors: J
authors: Veitch
authors: Anoushka
authors: A
authors: Kansara
authors: Daniel
authors: D
authors: Bailey
authors: Ildiko
authors: I
authors: Kustos
mesh_terms: D000328:Adult; D000881:Anthrax / Q000382:microbiology / Q000628:therapy*; D001408:Bacillus anthracis; D004340:Drug Contamination; D003932:Heroin; D006801:Humans; D013287:Illicit Drugs; D008297:Male; D018461:Soft Tissue Infections / Q000382:microbiology* / Q000628:therapy; D015819:Substance Abuse, Intravenous / Q000150:complications* / Q000382:microbiology
chemical_list: D013287:Illicit Drugs; D003932:Heroin