title: [Fluctuating headache with personality change in a 63 year old man].
abstract: We present a 63 year old man with new onset of fluctuating headache and behavioural changes showing marked inhibition and disorientation. After non invasive and invasive diagnostics an isolated cerebral vasculitis was found. Key results have been found in cerebral MRI and cerebral digital subtraction angiography with irregularities of vessel calibre of the intracerebral arteries. During treatment with high-dose corticosteroid therapy and Cyclophosphamid pulse therapy qualitative disorders and headache rapidly regressed. We discuss differential diagnosis of secondary headache, etiology of cerebral vasculitides, diagnostic challenge and therapy in isolated cerebral vasculitis.
authors: Medizinische Klinik, Kantonsspital Olten.
authors: Beatrice
authors: B
authors: Müller
authors: Neuroradiologie, Inselspital Bern.
authors: Pasquale
authors: P
authors: Mordasini
authors: Medizinische Klinik, Kantonsspital Olten.
authors: Stefano
authors: S
authors: Bassetti
authors: Medizinische Klinik, Kantonsspital Olten.
authors: Susanna
authors: S
authors: Frigerio
mesh_terms: D002533:Cerebral Angiography; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D004569:Electroencephalography; D006261:Headache / Q000209:etiology*; D051271:Headache Disorders, Secondary / Q000209:etiology*; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D010554:Personality Disorders / Q000209:etiology*; D012815:Signal Processing, Computer-Assisted; D020293:Vasculitis, Central Nervous System / Q000175:diagnosis*
keywords: Kopfschmerzen; Wesensveränderungen; changes of personality; headache; isolated cerebral vasculitis; isolierte zerebrale Vaskulitis