title: Quantitative cerebral blood flow measurements using MRI.
abstract: Magnetic resonance imaging can be utilized as a quantitative and noninvasive method to image cerebral blood flow. The two most common techniques used to detect cerebral blood flow are dynamic susceptibility contrast (DSC) perfusion MRI and arterial spin labeling perfusion MRI. Herein we describe the use of these two techniques to measure cerebral blood flow in rodents, including methods, analysis, and important considerations when utilizing these techniques.
authors: Department of Ophthalmology, Research Imaging Institute, University of Texas Health Science Center, San Antonio, TX, USA.
authors: Eric R
authors: ER
authors: Muir
authors: Lora Talley
authors: LT
authors: Watts
authors: Yash Vardhan
authors: YV
authors: Tiwari
authors: Andrew
authors: A
authors: Bresnen
authors: Qiang
authors: Q
authors: Shen
authors: Timothy Q
authors: TQ
authors: Duong
mesh_terms: D000818:Animals; D002560:Cerebrovascular Circulation; D003287:Contrast Media; D019786:Gadolinium DTPA; D018810:Magnetic Resonance Angiography; D051381:Rats; D012039:Regional Blood Flow; D013113:Spin Labels
chemical_list: D003287:Contrast Media; D013113:Spin Labels; D019786:Gadolinium DTPA