title: Why is perioperative chemotherapy for bladder cancer underutilized?
abstract: Despite clinical evidence and recommendations from international treatment guidelines, the use of perioperative chemotherapy for muscle-invasive bladder cancer in routine practice remains low. Although multiple studies have described underutilization, there is an urgent need to better understand the elements contributing to the observed gaps in care. In this commentary, we explore what is known about the factors contributing to underutilization of perioperative chemotherapy for muscle-invasive bladder cancer. We also propose a framework to guide future knowledge translation activities in an effort to improve the care and outcomes of patients with this disease.
authors: Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Canada.
authors: Francis M
authors: FM
authors: Patafio
authors: Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Canada.
authors: William J
authors: WJ
authors: Mackillop
authors: Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Canada.
authors: Deb
authors: D
authors: Feldman-Stewart
authors: Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Canada.
authors: David Robert
authors: DR
authors: Siemens
authors: Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Canada. Electronic address: boothc@kgh.kari.net.
authors: Christopher M
authors: CM
authors: Booth
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D006801:Humans; D019990:Perioperative Care / Q000706:statistics & numerical data*; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy*
keywords: bladder cancer; chemotherapy; health policy; knowledge translation; medical decision making; practice patterns; quality of care