title: Clinical features, management, and short- and long-term outcomes of patients with acute decompensated heart failure: phase I results of the HEARTS database.
abstract: OBJECTIVE
  The HEart function Assessment Registry Trial in Saudi Arabia (HEARTS) is a national multicentre project, studying clinical features, management, short- and long-term outcomes, and mortality predictors in patients admitted with acute decompensated heart failure (ADHF).
  
  
  RESULTS
  Our prospective registry enrolled 2610 ADHF patients admitted to 18 hospitals in Saudi Arabia between October 2009 and December 2010, and followed mortality rates until January 2013. The patients included 66% men and 85.5% Saudis, with a median age (interquartile range) of 61.4 (15) years; 64% had acute on chronic heart failure (HF), 64.1% diabetes mellitus, 70.6% hypertension, and 55.7% CAD. Exacerbating factors for hospital admission included acute coronary syndromes (37.8%), infections (20.6%), non-compliance with low-salt diet (25.2%), and non-compliance with HF medications (20%). An LVEF<40% was found in 73%. In-hospital use of evidence-based medications was high. All-cause cumulative mortality rates at 30 days, 6 months, 1 year, 2 years, and 3 years were 8.3, 13.7, 19.5, 23.5, and 24.3%, respectively. Important independent predictors of mortality were history of stroke, acute on chronic HF, systolic blood pressure<90 mmHg upon presentation, estimated glomerular filtration rate<60 mL/min, and haemoglobin<10 g/dL.
  
  
  CONCLUSIONS
  Patients with ADHF in Saudi Arabia presented at a younger age and had higher rates of CAD risk factors compared with those in developed countries. Most patients had reduced LV systolic function, mostly due to ischaemic aetiology, and had poor long-term prognosis. These findings indicate a need for nationwide primary prevention and HF disease management programmes.
authors: Khalid F
authors: KF
authors: AlHabib
authors: Abdelfatah A
authors: AA
authors: Elasfar
authors: Hussam
authors: H
authors: Alfaleh
authors: Tarek
authors: T
authors: Kashour
authors: Ahmad
authors: A
authors: Hersi
authors: Hanan
authors: H
authors: AlBackr
authors: Fayez
authors: F
authors: Alshaer
authors: Khalid
authors: K
authors: AlNemer
authors: Gamal A
authors: GA
authors: Hussein
authors: Layth
authors: L
authors: Mimish
authors: Ali
authors: A
authors: Almasood
authors: Waleed
authors: W
authors: AlHabeeb
authors: Saleh
authors: S
authors: AlGhamdi
authors: Mubrouk
authors: M
authors: Alsharari
authors: Esmail
authors: E
authors: Chakra
authors: Asif
authors: A
authors: Malik
authors: Raza
authors: R
authors: Soomro
authors: Abdullah
authors: A
authors: Ghabashi
authors: Mushabab
authors: M
authors: Al-Murayeh
authors: Ahmed
authors: A
authors: Abuosa
mesh_terms: D000328:Adult; D000368:Aged; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality; D016208:Databases, Factual; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006333:Heart Failure / Q000175:diagnosis* / Q000188:drug therapy* / Q000401:mortality; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012042:Registries; D012307:Risk Factors; D012529:Saudi Arabia / Q000453:epidemiology