title: Discordant twins as a tool to unravel the aetiology of bipolar disorder.
abstract: This editorial focuses on discordant twins as a valuable epidemiological design for psychiatric aetiological research. First, we summarise the advantages and strengths of this design over the classical matched case-control study. Then, we draw attention to the use of this method in bipolar disorder, revising previous discordant-twin studies. A future greater use of discordant twins is desirable to gain further relevant insights in the aetiology of bipolar disorder.
authors: Genetic Epidemiology Unit, National Centre of Epidemiology, Surveillance and Health Promotion, Italian National Institute of Health, Rome, Italy.
authors: C
authors: C
authors: Fagnani
authors: Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, Inter-University Centre for Behavioural Neurosciences (ICBN), University of Verona, Verona, Italy.
authors: M
authors: M
authors: Bellani
authors: Department of Psychiatry and Behavioral Sciences, UT Houston Medical School, Houston, TX, USA.
authors: J C
authors: JC
authors: Soares
authors: Genetic Epidemiology Unit, National Centre of Epidemiology, Surveillance and Health Promotion, Italian National Institute of Health, Rome, Italy.
authors: M A
authors: MA
authors: Stazi
authors: Department of Psychiatry and Behavioral Sciences, UT Houston Medical School, Houston, TX, USA.
authors: P
authors: P
authors: Brambilla