title: Fine needle aspiration cytology and frozen section in the diagnosis of malignant parotid tumours.
abstract: The aim of this study was to determine the value of fine needle aspiration cytology (FNAC) and frozen section (FS) in the diagnosis of malignant parotid tumours. One hundred and thirty-eight patients who underwent FNAC and FS of a parotid tumour between 2006 and 2011 were analyzed retrospectively. The sensitivity, specificity, and positive and negative predictive values of FNAC and FS were determined using final histological diagnosis as the gold standard. Of the 138 tumours assessed in our study, 30 were malignant and 108 benign. For FNAC, the sensitivity was 73%, specificity 87%, positive predictive value 61%, and negative predictive value 90%. For FS, the sensitivity was 80%, specificity 98%, positive predictive value 92%, and negative predictive value 94%. Four false-negative results by FNAC were corrected by FS, and surgery was completed. Two false-positive results were identified by both FNAC and FS. FNAC is an important examination that provides valuable information for the preoperative diagnostic work-up and alerts the surgeon to the possible presence of malignancy. However, FNAC cannot be used alone, and FS has a very important place in the intraoperative management of parotid tumours.
authors: Service d'ORL et Chirurgie Cervico-Faciale, Centre Hospitalier Universitaire La Timone, Aix-Marseille Univ, 264 rue Saint Pierre, 13385 Marseille Cedex 05, France. Electronic address: nicolas.fakhry@ap-hm.fr.
authors: N
authors: N
authors: Fakhry
authors: Service d'ORL et Chirurgie Cervico-Faciale, Centre Hospitalier Universitaire La Timone, Aix-Marseille Univ, 264 rue Saint Pierre, 13385 Marseille Cedex 05, France.
authors: L
authors: L
authors: Santini
authors: Service d'ORL et Chirurgie Cervico-Faciale, Centre Hospitalier Universitaire La Timone, Aix-Marseille Univ, 264 rue Saint Pierre, 13385 Marseille Cedex 05, France.
authors: A
authors: A
authors: Lagier
authors: Service d'ORL et Chirurgie Cervico-Faciale, Centre Hospitalier Universitaire La Timone, Aix-Marseille Univ, 264 rue Saint Pierre, 13385 Marseille Cedex 05, France.
authors: P
authors: P
authors: Dessi
authors: Service d'ORL et Chirurgie Cervico-Faciale, Centre Hospitalier Universitaire La Timone, Aix-Marseille Univ, 264 rue Saint Pierre, 13385 Marseille Cedex 05, France.
authors: A
authors: A
authors: Giovanni
mesh_terms: D044963:Biopsy, Fine-Needle / Q000379:methods*; D005260:Female; D005629:Frozen Sections; D006801:Humans; D008297:Male; D010307:Parotid Neoplasms / Q000473:pathology* / Q000601:surgery; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
keywords: head and neck tumour; parotid gland; salivary glands; surgery