title: Validity of the Global Registry of Acute Coronary Events risk score in prediction of acute myocardial infarction mortality in hospitalised Chinese patients aged 80 and over.
abstract: OBJECTIVE
  To detect the validity of the Global Registry of Acute Coronary Events (GRACE) risk score in predicting acute myocardial infarction (AMI) mortality of Chinese inpatients aged 80 and over.
  
  
  METHODS
  Hospital mortality was defined as all-cause death rate of patients during hospitalisation. Using GRACE risk score to predict death risk, both discrimination (C statistic) and calibration (the predicted vs observed mortality based on the population with predicted risks) were evaluated.
  
  
  RESULTS
  Three hundred eighty-six patients presenting with ST segment elevation AMI (STEMI) and non-STEMI were enrolled. The GRACE risk score ranged between 151 and 297, and the mortality was 23.3%. The overall discriminatory capacity of the GRACE model was high (C statistic 0.767, CI: 0.712-0.822). There was a high correlation (R(2) = 0.833) between the predicted and observed hospitalised AMI mortality.
  
  
  CONCLUSIONS
  The GRACE score is a useful risk prediction model for hospital mortality of Chinese AMI patients aged 80 and over.
authors: Department of Cardiology, Fu Xing Hospital, Capital Medical University, Beijing, China.
authors: Jing-guang
authors: JG
authors: Luo
authors: Ming
authors: M
authors: Yang
authors: Ling
authors: L
authors: Han
authors: Li-Wei
authors: LW
authors: Chen
authors: Xin
authors: X
authors: Chen
authors: Kang
authors: K
authors: Gao
authors: Xiao-Hong
authors: XH
authors: Li
authors: Ping
authors: P
authors: Chen
mesh_terms: D000367:Age Factors; D000369:Aged, 80 and over; D019540:Area Under Curve; D044466:Asian People; D002681:China / Q000453:epidemiology; D003661:Decision Support Techniques; D016002:Discriminant Analysis; D005260:Female; D015577:Geriatric Assessment; D017052:Hospital Mortality / Q000208:ethnology*; D006801:Humans; D007297:Inpatients; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis / Q000208:ethnology / Q000401:mortality* / Q000628:therapy; D012372:ROC Curve; D015203:Reproducibility of Results; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors
keywords: aged 80 and over; hospital mortality; myocardial infarction; predictive value of tests; reproducibility of results