title: The endothelial-mesenchymal transition (EndMT) and tissue regeneration.
abstract: Recent studies have brought endothelial-mesenchymal transition (EndMT) as a special perspective of epithelial- mesenchymal transition (EMT) into eyes. Traditionally, EndMT is considered as a source for fibroblasts and myofibroblasts, and it is extensively investigated in physiologic cardiac development as well as in pathologic tumor and fibrosis. Recently, new studies have found that EndMT-transformed cells had 'stemness', which means they could differentiate into chondroblasts, osteoblasts, and adipoblasts in differential culture, respectively. This gives EndMT a bright application future in tissue engineering and regeneration, especially for the formation of cartilage and bone.
authors: Wenjing
authors: W
authors: Yu
authors: Zhen
authors: Z
authors: Liu
authors: Shu
authors: S
authors: An
authors: Jinyi
authors: J
authors: Zhao
authors: Lan
authors: L
authors: Xiao
authors: Yongchao
authors: Y
authors: Gou
authors: Yunfeng
authors: Y
authors: Lin
authors: State Key Laboratory of Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, No.14, 3rd section, People's South Road, Chengdu, Sichuan 610041, China. wangjunv@scu.edu.cn.
authors: Jun
authors: J
authors: Wang
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D004727:Endothelium / Q000166:cytology*; D006801:Humans; D008648:Mesoderm / Q000166:cytology*; D012038:Regeneration / Q000502:physiology*; D023822:Tissue Engineering