title: Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 3: a status report on systemic therapies.
abstract: The third article in this 5-part series reviews systemic therapies used to treat cutaneous rosacea based on consensus recommendations from the American Acne & Rosacea Society (AARS) on the management of the common presentations of cutaneous rosacea. The consensus recommendations are based on current understanding of research that describes pathophysiologic mechanisms that appear to be operative in rosacea, correlation of these underlying pathophysiologic mechanisms with specific clinical manifestations of rosacea, and outcomes from clinical trials that evaluate therapies for rosacea both as monotherapy and in combination with other agents. Systemic agents used for treatment of rosacea have been administered as oral formulations (ie, tablets, capsules). The only oral agent for rosacea approved by the US Food and Drug Administration (FDA) is a modified-release doxycycline 40-mg capsule. Other non-FDA-approved oral agents also are discussed including other tetracyclines, macrolides, metronidazole, and isotretinoin.
authors: jqdelrosso@yahoo.com.
authors: James Q
authors: JQ
authors: Del Rosso
authors: Diane
authors: D
authors: Thiboutot
authors: Richard
authors: R
authors: Gallo
authors: Guy
authors: G
authors: Webster
authors: Emil
authors: E
authors: Tanghetti
authors: Lawrence F
authors: LF
authors: Eichenfield
authors: Linda
authors: L
authors: Stein-Gold
authors: Diane
authors: D
authors: Berson
authors: Andrea
authors: A
authors: Zaenglein
mesh_terms: D000284:Administration, Oral; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D017277:Drug Approval; D006801:Humans; D012393:Rosacea / Q000188:drug therapy* / Q000503:physiopathology; D012955:Societies, Medical; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D003879:Dermatologic Agents