title: The properties of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) and its applications in tissue engineering.
abstract: Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) is a member of the polyhydroxyalkanoate (PHA) family. It is the designation of molecules consisting of random co-polymers of 3-hydroxybutyrate and 3- hydroxyhexanoate. PHBHHx plays a significant role in the field of biomedical materials. It has good physical, chemical and mechanical properties, making it potentially useful for a wide range of biomaterials applications. In addition, it has also shown better biocompatibility with different cell types. This paper will introduce the physical, chemical and biological properties of PHBHHx, including biodegradation, hydrophilicity, surface properties and cytocompatibility. The development of PHBHHx in tissue-engineering applications will be discussed. PHBHHx used to repair bone, cartilage, tendons, nerves and vessels will be the focus of discussion.
authors: Qixiang
authors: Q
authors: Yang
authors: Jing
authors: J
authors: Wang
authors: Shu
authors: S
authors: Zhang
authors: Xiaoshan
authors: X
authors: Tang
authors: Guangwei
authors: G
authors: Shang
authors: Qiang
authors: Q
authors: Peng
authors: Raorao
authors: R
authors: Wang
authors: Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, No. 301., Middle Yanchang Road, Shanghai 200072, P.R. China. raoraowang@tongji.edu.cn.
authors: Xiaoxiao
authors: X
authors: Cai
mesh_terms: D020155:3-Hydroxybutyric Acid / Q000737:chemistry*; D000818:Animals; D002208:Caproates / Q000737:chemistry*; D006801:Humans; D023822:Tissue Engineering / Q000379:methods*; D000094122:Polyhydroxybutyrates
chemical_list: D020155:3-Hydroxybutyric Acid; D002208:Caproates; C115940:poly(3-hydroxybutyrate-co-3-hydroxyhexanoate); D000094122:Polyhydroxybutyrates