title: Alkyltriflate-triggered annulation of arylisothiocyanates and alkynes leading to multiply substituted quinolines through domino electrophilic activation.
abstract: The reaction of arylisothiocyanate, alkyltriflate, and alkynes leads to variously substituted quinolines in high yields. The reaction undergoes alkyltriflate-triggered domino electrophilic activation and avoids the use of a transition-metal catalyst. A variety of functional groups are tolerated in the quinoline ring.
authors: Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University , Beijing 100084, China.
authors: Peng
authors: P
authors: Zhao
authors: Xiaoyu
authors: X
authors: Yan
authors: Hang
authors: H
authors: Yin
authors: Chanjuan
authors: C
authors: Xi
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D053119:Benzophenanthridines / Q000138:chemical synthesis / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013861:Thiocyanates / Q000737:chemistry*
chemical_list: D000480:Alkynes; D053119:Benzophenanthridines; D011804:Quinolines; D013861:Thiocyanates