title: Psychometric properties and validation of Persian version of quality of life in epilepsy inventory (QOLIE-89).
abstract: BACKGROUND
  Several epilepsy-specific quality of life questionnaires have been developed. One of them is quality of life in epilepsy-89 version. The objective of this study was to develop a Persian version of QOLE-89 and confirm its psychometric properties.
  
  
  METHODS
  Participants were 75 patients with epilepsy. The quality of life questionnaire was adapted to Persian language through a translation and translation-back procedure. Internal consistency by Cronbach's α, was determined and construct validity was assessed by correlation with GHQ-12 and BDI-PC and discriminant validity was confirmed by comparing scores for known groups.
  
  
  RESULTS
  Reliability based on internal consistency (Cronbach's α) for QOIE-89 was 0/96 and for 17 subscales was varied form 0/70 to 0/89 and Test-retest reliability (Pearson's correlation coefficient) for the Farsi version of the QOLIE-89 ranged from 0.75 to 0.88. Total score of QOLIE-89 discriminated well between the patients according to depression severity and drug resistance and seizure controllability. Correlation between the total scores, BDI-PC and GHQ-R to confirm construct validity was 0/55 and 0/63, respectively.
  
  
  CONCLUSIONS
  In this cross-sectional survey, Persian version of the QOLIE-89 was reliable and showed properties supporting the construct and discriminant validity at a level comparable with the original and some other versions. Thus, this questionnaire has suitable properties in Iranian population and can be used in clinical trials with epileptic patients.
authors: Behavioral Sciences Research Center, Department of Psychiatry, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Amrollah
authors: A
authors: Ebrahimi
authors: Psychosomatic Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Majid
authors: M
authors: Barekatain
authors: Behavioral Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Alireza
authors: A
authors: Bornamanesh
authors: Department of Neurology, Alzahra Haspital, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Mohammad Reza
authors: MR
authors: Najafi
authors: Department of psychology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Maryam
authors: M
authors: Salehzadeh
authors: Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Mohammad Reza
authors: MR
authors: Maracy
keywords: Epilepsy; QOLIE-89 validity; psychometric properties; quality of life; reliability; seizure; sensitivity; specificity