title: Long-term, high-dose intravenous immunoglobulin therapy in a patient with banker-type juvenile dermatomyositis.
abstract: Juvenile dermatomyositis (JDM) is a multisystem disease characterized by non-purulent inflammation in the striated muscle and skin. Banker-type JDM is difficult to treat and control, especially when it is a form that is resistant to steroid treatment. Here, we report a 2-year-old girl with Banker-type JDM resistant to steroid treatment. The patient received intravenous immunoglobulin (IVIg) at 400 mg/kg/5 days a week every 6 weeks. Motor function improved and the patient was able to walk after six cycles. IVIg was administered every four weeks for six cycles thereafter, and the patient was able to walk more quickly with an improvement in quality of life. No apparent adverse effects were observed during IVIg treatment.
authors: Department of Pediatrics, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi, 321-0293, Japan, geo@dokkyomed.ac.jp.
authors: George
authors: G
authors: Imataka
authors: Osamu
authors: O
authors: Arisaka
mesh_terms: D002675:Child, Preschool; D003882:Dermatomyositis / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D004351:Drug Resistance / Q000187:drug effects; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D013256:Steroids / Q000627:therapeutic use; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous; D013256:Steroids