title: A photochemical method for determining plasma homocysteine with limited sample processing.
abstract: The photolytic formation of thiyl radicals allows for the selective detection of total homocysteine (tHcy) in plasma after reduction and filtering. The mechanism is based on the reduction of viologens by the α-amino carbon centred radical of Hcy generated by intramolecular hydrogen atom transfer (HAT) of its thiyl radical.
authors: Department of Chemistry, Portland State University, Portland, Oregon 97207, USA. strongin@pdx.edu.
authors: Lovemore
authors: L
authors: Hakuna
authors: Jorge O
authors: JO
authors: Escobedo
authors: Mark
authors: M
authors: Lowry
authors: Aabha
authors: A
authors: Barve
authors: Naneki
authors: N
authors: McCallum
authors: Robert M
authors: RM
authors: Strongin
mesh_terms: D002244:Carbon / Q000737:chemistry; D006710:Homocysteine / Q000032:analysis / Q000097:blood*; D006801:Humans; D006859:Hydrogen / Q000737:chemistry; D010084:Oxidation-Reduction; D010782:Photolysis; D014755:Viologens / Q000737:chemistry
chemical_list: D014755:Viologens; D006710:Homocysteine; D002244:Carbon; D006859:Hydrogen