title: Inpatient antibiotic consumption in a regional secondary hospital in New Zealand.
abstract: BACKGROUND
  Reporting of antibiotic consumption in hospitals is a crucial component of antibiotic stewardship, but data from Australasian secondary hospitals are scarce. The hypothesis of this audit is that antibiotic consumption in secondary hospitals would be lower than in tertiary centres.
  
  
  OBJECTIVE
  The study aims to present the first published audit of antibiotic consumption from a secondary hospital in New Zealand compared with two tertiary centres.
  
  
  METHODS
  Hospital population-level data were retrospectively accessed to identify all systemic antibiotics dispensed to adult inpatients at Taranaki District Health Board during 2011. Consumption was calculated in defined daily doses per 100 inpatient-days and per 100 admissions, stratified by drug class. Comparison was against published data from two tertiary centres.
  
  
  RESULTS
  Total consumption was lower, but that of high-risk antibiotic classes was higher than both tertiary centres. The relative consumption of lincosamides was 4.0 and 2.6 times higher than the two tertiary centres, with an associated 14% incidence of Clostridium difficile associated diarrhoea within 3 months.
  
  
  CONCLUSIONS
  Our secondary hospital appears to consume the wrong types of antibiotic rather than too much. Data from all Australasian hospitals, stratified by clinical service area and hospital level, are required for clinically relevant benchmarking.
authors: Department of Medicine, Taranaki Base Hospital, New Plymouth, New Zealand.
authors: C J
authors: CJ
authors: Hopkins
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000145:classification / Q000627:therapeutic use; D054869:Clinical Audit; D062313:Databases, Pharmaceutical / Q000706:statistics & numerical data; D004363:Drug Utilization / Q000706:statistics & numerical data*; D005260:Female; D006301:Health Services Needs and Demand; D006780:Hospitals, Rural / Q000706:statistics & numerical data; D006801:Humans; D007297:Inpatients / Q000706:statistics & numerical data*; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008508:Medication Errors / Q000517:prevention & control* / Q000706:statistics & numerical data; D009520:New Zealand; D012189:Retrospective Studies; D063728:Secondary Care Centers / Q000706:statistics & numerical data
chemical_list: D000900:Anti-Bacterial Agents
keywords: New Zealand; antibacterial agents/therapeutic use; drug resistance; pharmacy service; secondary care/statistics and numerical data