title: Alterations in fatty acids of polar lipids in Salmo trutta on long-term exposure to a glyphosate-based herbicide (Roundup).
abstract: Abstract: In present study, the effects of sublethal doses (10 and 20 mg L(-1)) of Roundup on fatty acid pattern in muscle and liver of brown trout were investigated. For this purpose, fish were held in experiment tanks for 1 month. While total MUFA wasn't influenced, the highest total SFA and total n-6 PUFA were determined in group 10 mg L(-1) and the lowest values were determined in control group and group 20 mg L(-1) in muscle, respectively. The highest and the lowest total n-3 PUFA was found in control group and group of 10 mg L(-1) in muscle, respectively. Total n-3/n-6 PUFA ratio and EPA+DHA level of group 10 mg L(-1) were lower than other groups in muscle. The amount of total n-3/n-6 PUFA, EPA + DHA and total n-3 PUFA of control group were found higher than treatment groups in liver. While the highest total SFA was determined in group 10 mg L(-1), there wasn't difference between control group and group 20 mg L(-1) in liver. Both of doses herbicide had higher value than control for total MUFA in liver. While Roundup didn't inhibit n-3 PUFA synthesis in the muscle, both concentrations, exhibited inhibitory effect on n-3 PUFA synthesis in the liver. This result probably consequence of its indirect effect on the some enzyme activities or gene expressions in fatty acid metabolism of brown trout.
authors: Department of Agricultural Biotechnology, Faculty of Agriculture, Ataturk University, 25240, Erzurum, Turkey.
authors: Mehtap
authors: M
authors: Bayir
authors: Department of Agricultural Biotechnology, Faculty of Agriculture, Ataturk University, 25240, Erzurum, Turkey.
authors: A Necdet
authors: AN
authors: Sirkecioglu
authors: Department of Aquaculture, Faculty of Fisheries, Ataturk University, 25240, Erzurum, Turkey.
authors: Abdulkadir
authors: A
authors: Bayir
authors: Department of Aquaculture, Faculty of Fisheries, Ataturk University, 25240, Erzurum, Turkey.
authors: Mevlut
authors: M
authors: Aras
mesh_terms: D000818:Animals; D005227:Fatty Acids / Q000378:metabolism*; D015525:Fatty Acids, Omega-3 / Q000378:metabolism*; D043371:Fatty Acids, Omega-6 / Q000378:metabolism*; D005399:Fishes / Q000378:metabolism*; D005998:Glycine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000633:toxicity; D006540:Herbicides / Q000737:chemistry / Q000633:toxicity*; D050356:Lipid Metabolism / Q000187:drug effects*; D008099:Liver / Q000187:drug effects; D009132:Muscles / Q000187:drug effects; D000097797:Glyphosate
chemical_list: D005227:Fatty Acids; D015525:Fatty Acids, Omega-3; D043371:Fatty Acids, Omega-6; D005998:Glycine; D006540:Herbicides; D000097797:Glyphosate