title: Total syntheses of secalonic acids A and D.
abstract: Total syntheses of the dimeric tetrahydroxanthone natural products secalonic acids A and D are described. Key steps involve kinetic resolution of the tetrahydroxanthone core structure using homobenzotetramisole catalysis and late-stage copper(I)-mediated homodimerization of complex aryl stannane monomers.
authors: Department of Chemistry and Center for Chemical Methodology and Library Development (CMLD-BU), Boston University, 590 Commonwealth Avenue, Boston, MA 02215 (USA).
authors: Tian
authors: T
authors: Qin
authors: John A
authors: JA
authors: Porco
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D013237:Stereoisomerism; D044004:Xanthones / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D001688:Biological Products; D044004:Xanthones; C009218:secalonic acid
keywords: dimerization; kinetic resolution; natural products; stannanes; total synthesis