title: Anti-inflammatory effect of Chandrashura (Lepidium sativum Linn.) an experimental study.
abstract: Lepidium sativum Linn. (Chandrashura) of Family Cruciferae (Brassicaceae) is being used by the people of Gujarat for treating inflammatory condition like arthritis. To evaluate its anti-inflammatory activity, Charles Foster albino rats were selected and experiments were carried out in three groups, therapeutic dose group, twice of therapeutic dose group and control group. In Carrageenan-induced paw oedema, the test drug produced moderate anti-inflammatory activity; however, the effect did not show statistically significant activity due to variation in the data of the control group. In formaldehyde-induced paw oedema in rats, the test drug produced moderate to significant suppression. This indicates that Chandrashura has a strong inhibitory effect on proliferation of fibroblasts and also probably has connective tissue modulation effect.
authors: Lecturer, Department of Dravyaguna, Government Ayurvedic Collage, Junagadh, Gujarat, India.
authors: Nita D
authors: ND
authors: Raval
authors: Director, SDM Research Centre for Ayurveda and Allied Sciences, Kuthpady, Udupi, India.
authors: B
authors: B
authors: Ravishankar
authors: Drug Discovery Team, Research and Development, The Himalaya Drug Company, Makali, Bangalore, Karnataka, India.
authors: B K
authors: BK
authors: Ashok
keywords: Anti-Inflammatory; Chandrashura (Lepidium sativum Linn.); carrageenan and formaldehyde-induced paw oedema