title: A hydrosurgery system (Versajet) with and without hydrogen peroxide solutions for the debridement of subacute and chronic wounds: a comparative study with hydrodebridement.
abstract: OBJECTIVE
  The aim of this study was to evaluate the efficacy of hydrosurgery prepared with or without hydrogen peroxide for the management of subacute and chronic wounds.
  
  
  METHODS
  This is a retrospective study on patients with infected subacute and chronic wounds. The wounds were debrided using hydrosurgery prepared with (the study group) or without hydrogen peroxide before grafting the wound (the control group).
  
  
  RESULTS
  There were 60 patients in the study group and 70 patients in the control group. The hospital stay (mean, 7.83 [SD, 2.16] vs 9.86 [SD, 3.41] days; P < .001) and graft viability (mean, 3 [2-3] vs 2 [2-3]; P = .001) were significantly better in the study group than in the control group. The difference of hemoglobin levels after surgery was also significantly lower in the study group (0.1 [0-0.48] vs 0.45 [0-1]; P = .004).
  
  
  CONCLUSIONS
  Encouraging results were obtained with the use of the hydrosurgery system prepared with hydrogen peroxide for infected subacute and chronic wounds. This method decreased hospital stay and bleeding, thus providing better contact of the skin graft with the wound bed, allowing early rehabilitation. The findings of the authors' study need to be substantiated in large-scale randomized controlled trials.
authors: Saime Irkoren, MD, and Nazan Sivrioglu, MD, are both Assistant Professors, Plastic and Reconstructive Surgery Department, Medical Faculty, Adnan Menderes University, Aydin, Turkey.
authors: Saime
authors: S
authors: Irkoren
authors: Nazan
authors: N
authors: Sivrioglu
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003646:Debridement / Q000295:instrumentation* / Q000379:methods; D005260:Female; D006085:Graft Survival; D006801:Humans; D006861:Hydrogen Peroxide / Q000627:therapeutic use*; D007223:Infant; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018570:Risk Assessment; D016038:Skin Transplantation / Q000379:methods; D018709:Statistics, Nonparametric; D016896:Treatment Outcome; D014421:Turkey; D014867:Water / Q000008:administration & dosage*; D014945:Wound Healing / Q000502:physiology; D014947:Wounds and Injuries / Q000175:diagnosis / Q000601:surgery*; D055815:Young Adult
chemical_list: D014867:Water; D006861:Hydrogen Peroxide