title: [Treatment of premature ovarian failure patients of Shen Yang deficiency syndrome by warming Shen, enhancing Yang, invigorating qi, and nourishing blood method combined artificial cycle therapy: a clinical observation].
abstract: OBJECTIVE
  To observe the clinical efficacy of warming Shen, enhancing Yang, invigorating qi, and nourishing blood method (WSEYIQNBM) combined artificial cycle therapy in treatment of premature ovarian failure (POF) patients of Shen yang deficiency syndrome (SYDS).
  
  
  METHODS
  Totally 96 POF patients of SYDS were randomly assigned to the treatment group and the control group, 48 in each group. Patients in the treatment group were treated with WSEYIQNBM combined artificial cycle therapy, while those in the control group were treated with Western medicine artificial cycle therapy. One month constituted 1 course, a total of 3 courses. The menstruation and main symptoms were observed before and after treatment. Serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) were detected before and after treatment.
  
  
  RESULTS
  The total effective rate was 85.43% in the treatment group, higher than that of the control group (79.17%, P < 0.05). Besides, better effect in improving Chinese medical symptoms was obtained in the treatment group (P < 0.05).
  
  
  CONCLUSIONS
  POF patients' serum hormone levels and clinical symptoms could be improved by WSEYIQNBM combined artificial cycle therapy.
authors: Shandong Qingzhou Hospital of Traditional Chinese Medicine, Shandong 262500, China. qzwsjcq@163.com
authors: Qian
authors: Q
authors: Cui
authors: Shandong Qingzhou People's Hospital, Shandong 262500, China.
authors: Zhi-Qin
authors: ZQ
authors: Ji
authors: Shandong Qingzhou Maternal and Child Health Institute, Shandong 262500, China.
authors: Jing
authors: J
authors: Feng
mesh_terms: D000328:Adult; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004958:Estradiol / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008517:Phytotherapy; D016649:Primary Ovarian Insufficiency / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D004365:Drugs, Chinese Herbal; D004958:Estradiol