title: Synergy-S stereotactic radiosurgery for spinal tumors.
abstract: BACKGROUND
  Radiation treatment of spinal and paraspinal tumors has been limited by the tolerance of the spinal cord. As such, therapeutic options are restricted to surgically accessible lesions or the use of suboptimal dosing of external beam irradiation.
  
  
  OBJECTIVE
  To evaluate the safety and applicability of the Elekta Synergy-S radiation unit for the treatment of spinal tumors.
  
  
  METHODS
  We retrospectively reviewed all patients treated with stereotactic radiosurgery for spinal tumors between November 2007 and June 2011.
  
  
  RESULTS
  Thirty-four patients were treated for 41 lesions. Treatment indications were local tumor control and pain palliation. The mean follow-up was 10.8 +/- 11.6 months (range 0.5-38 months). No acute radiation toxicity or new neurological deficits occurred during the follow-up period. Local tumor control was achieved in 21 of the 24 lesions (87.5%) available for radiological follow-up at a median of 9.8 months (range 3-32 months). Good analgesia was achieved in 24/30 lesions (80%) that presented with intractable pain.
  
  
  CONCLUSIONS
  The safety and feasibility of delivering single and multiple-fraction stereotactic spinal irradiation was demonstrated and became a standard treatment option in our institution.
authors: Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors: Ido
authors: I
authors: Strauss
authors: Diagnostic Neuroradiology Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors: Tali
authors: T
authors: Jonas-Kimchi
authors: Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors: Zvi
authors: Z
authors: Lidar
authors: Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors: Dana
authors: D
authors: Buchbut
authors: Department of Radiation Therapy, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors: Natan
authors: N
authors: Shtraus
authors: Department of Radiation Therapy, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors: Benjamin W
authors: BW
authors: Corn
authors: Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors: Andrew A
authors: AA
authors: Kanner
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010148:Intractable Pain / Q000209:etiology / Q000601:surgery*; D016634:Radiosurgery / Q000009:adverse effects / Q000379:methods*; D012189:Retrospective Studies; D013125:Spinal Neoplasms / Q000473:pathology / Q000601:surgery*; D013238:Stereotaxic Techniques; D016896:Treatment Outcome