title: Efficient inhibition of human papillomavirus 16 L1 pentamer formation by a carboxylatopillarene and a p-sulfonatocalixarene.
abstract: Pillarenes and calixarenes showed obvious inhibition of HPV16 L1 pentamer formation via their selective binding to Arg and Lys residues at the monomer interface, which was reversible after the release of cyclic arenes. Pillarenes are more effective than calixarenes in terms of the inhibition efficiency, attributing to the different kinetics and binding affinity.
authors: State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, 130012, China. yqwu@jlu.edu.cn ywyang@jlu.edu.cn.
authors: Dong-Dong
authors: DD
authors: Zheng
authors: Ding-Yi
authors: DY
authors: Fu
authors: Yuqing
authors: Y
authors: Wu
authors: Yu-Long
authors: YL
authors: Sun
authors: Li-Li
authors: LL
authors: Tan
authors: Ting
authors: T
authors: Zhou
authors: Shi-Qi
authors: SQ
authors: Ma
authors: Xiao
authors: X
authors: Zha
authors: Ying-Wei
authors: YW
authors: Yang
mesh_terms: D047250:Calixarenes / Q000737:chemistry / Q000494:pharmacology*; D052162:Human papillomavirus 16 / Q000187:drug effects* / Q000378:metabolism; D010636:Phenols / Q000737:chemistry / Q000494:pharmacology*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D010636:Phenols; D000644:Quaternary Ammonium Compounds; C511968:p-sulfonatocalix(4)arene; C570642:pillar(5)arene; D047250:Calixarenes