title: Clinical significance of heterotopic ossification after metal-on-metal total hip resurfacing.
abstract: Few studies about how heterotopic ossification (HO) affects functional outcome after metal-on-metal total hip resurfacing (MOMHR) have been reported. The purpose of this study was to evaluate the incidence and clinical significance of HO after MOMHR. We retrospectively reviewed 122 consecutive patients, who underwent MOMHR from June 2006 to October 2008, with adequate follow-up information. All patients had four weeks of aspirin (325 mg twice a day) for DVT prophylaxis and two weeks of celecoxib (400 mg once a day) for pain control. All data were collected prospectively including radiographs and functional scores preoperatively, at three months and at one year postoperatively. An independent musculoskeletal radiologist, using the Brooker classification, reviewed radiographs. Unbalanced ANOVA analyses were performed to evaluate the effect of HO on outcome. The overall incidence of HO at three months was 62.1% (grade 1: 39.8%, grade 2: 20.4%, grade 3: 1.9%) and 75% at one year (grade 1: 41.7%, grade 2: 27.8%, grade 3: 5.5%). There were no significant differences in the functional status scores among Brooker grade 0 to 3 groups at three months and one year follow-up. The incidence of HO after MOMHR was 62.1% at three months and 75% at one year despite a post-operative regimen of aspirin and celecoxib. We found no evidence that predominantly Brooker grade 1 or 2 HO affected the clinical outcome at three months or one year when compared across all Brooker classes of patients.
authors: New York Presbyterian at Columbia University Medical Center, New York - USA.
authors: Jeffrey A
authors: JA
authors: Geller
authors: Wenbao
authors: W
authors: Wang
authors: Amrit
authors: A
authors: Goyal
authors: Barthelemy
authors: B
authors: Liabaud
authors: Marc
authors: M
authors: Brown
mesh_terms: D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D015897:Comorbidity; D005260:Female; D005271:Femur Head Necrosis / Q000601:surgery; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D061825:Metal-on-Metal Joint Prostheses; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000000981:diagnostic imaging / Q000453:epidemiology*; D015207:Osteoarthritis, Hip / Q000601:surgery; D011859:Radiography