title: State of the art in oncology: high risk neuroblastoma, alveolar rhabdomyosarcoma, desmoplastic small round cell tumor, and POST-TEXT 3 and 4 hepatoblastoma.
abstract: Despite advances in the treatment of pediatric cancers during the past few decades, high-risk neuroblastoma, alveolar rhabdomyosarcoma, desmoplastic small round cell tumor, and hepatoblastomas with 3 or 4 sector involvement after chemotherapy continue to present significant challenges. This review summarizes recent research on the management of these diseases, with a special focus on the use of surgical debulking, genetic analysis, immunotherapy, and chemotherapy in improving outcomes of patients with these solid tumors.
authors: Memorial Sloan-Kettering Cancer Center, New York, New York. Electronic address: laquaglm@mskcc.org.
authors: Michael P
authors: MP
authors: La Quaglia
mesh_terms: D002648:Child; D058405:Desmoplastic Small Round Cell Tumor / Q000473:pathology / Q000628:therapy*; D018197:Hepatoblastoma / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000628:therapy*; D008495:Medical Oncology / Q000639:trends*; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000473:pathology / Q000628:therapy*; D018232:Rhabdomyosarcoma, Alveolar / Q000473:pathology / Q000628:therapy*; D015996:Survival Rate
keywords: Alveolar rhabdomyosarcoma; Desmoplastic small round cell tumor; Hepatoblastoma; Neuroblastoma