title: Role of infections.
abstract: This article represents a review of the current literature on the role of infection in the pathogenesis of chronic obstructive pulmonary disease (COPD), in stable disease, exacerbations, and pneumonia. It outlines the complex interactions between respiratory pathogens and host immune defenses that underlie the clinical manifestations of infection in COPD.
authors: Pulmonary and Critical Care Medicine, University at Buffalo, SUNY, 3435 Main Street, Buffalo, NY 14214, USA.
authors: Kamen
authors: K
authors: Rangelov
authors: Pulmonary, Critical Care, and Sleep Medicine, VA Western New York Healthcare System, University at Buffalo, The State University of New York, 3495 Bailey Avenue, Buffalo, NY 14215, USA. Electronic address: ssethi@buffalo.edu.
authors: Sanjay
authors: S
authors: Sethi
mesh_terms: D001424:Bacterial Infections / Q000150:complications; D002908:Chronic Disease; D006801:Humans; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications* / Q000503:physiopathology; D012141:Respiratory Tract Infections / Q000150:complications* / Q000503:physiopathology; D014777:Virus Diseases / Q000150:complications
keywords: Airway colonization; Chronic infection; Infection in COPD; Innate immunity in COPD; New strain exacerbations; Pneumonia and COPD; Vicious-circle hypothesis; Virulence factors