title: The efficacy and safety of intense focused ultrasound in the treatment of enlarged facial pores in Asian skin.
abstract: BACKGROUND
  Intense focused ultrasound (IFUS) has been used successfully for skin tightening.
  
  
  OBJECTIVE
  To investigate the efficacy of IFUS in treating enlarged pores and to evaluate changes in skin elasticity and sebum production following IFUS.
  
  
  METHODS
  Twenty-two subjects with enlarged pores were randomized to receive a single treatment with IFUS using 1.5-mm transducer on one side of the face, and 3.0-mm transducer on the other. OBJECTIVE clinical assessments were made by blinded photographic evaluation. Subjective satisfaction and adverse effects were evaluated. Measurements of elasticity and sebum were performed at baseline, 3 and 6 weeks post-treatment.
  
  
  RESULTS
  Physicians' evaluation showed clinical pore improvements in 86% and 91% of the IFUS-treated sites using 1.5-mm and 3.0-mm transducer, respectively. The mean improvement scores were 1.7 and 1.9 for 1.5-mm and 3.0-mm transducer, respectively, with no statistical differences. Cutometer measurement demonstrated a significant improvement in skin elasticity. Sebum level showed a reduction without statistical significance. There was a positive correlation between improvement in elasticity and pore improvement grades. All treatments were well tolerated without significant side effects.
  
  
  CONCLUSIONS
  IFUS using 1.5-mm or 3.0-mm transducer was safe and effective for reducing enlarged pores in Asian skin with an improvement in skin elasticity.
authors: Department of Dermatology, CHA Bundang Medical Center, CHA University , Korea and.
authors: Hee Jung
authors: HJ
authors: Lee
authors: Kyung Real
authors: KR
authors: Lee
authors: Jae Yang
authors: JY
authors: Park
authors: Moon Soo
authors: MS
authors: Yoon
authors: Sang Eun
authors: SE
authors: Lee
mesh_terms: D000328:Adult; D044466:Asian People; D003357:Cosmetic Techniques / Q000009:adverse effects; D005145:Face; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D010781:Photography; D012060:Rejuvenation; D012867:Skin / Q000473:pathology*; D014464:Ultrasonic Therapy / Q000009:adverse effects / Q000379:methods*; D055815:Young Adult
keywords: Enlarged facial pores; intense focused ultrasound; skin elasticity