title: Microbial transformation of oleanolic acid by Trichothecium roseum.
abstract: Microbial transformation of the oleanolic acid (1) using Trichothecium roseum (pers.) Link (M 95.56) has resulted in the isolation of two new hydroxylated type metabolites, characterized as 15α-hydroxy-3-oxo-olean-12-en-28-oic acid (2) and 7β,15α-dihydroxy-3-oxo-olean-12-en-28-oic acid (3). The structure elucidation of these metabolites was based primarily on HR-EIMS, 1D NMR, and 2D NMR analyses.
authors: a State Key Laboratory of Bioactive Substance and Function of Natural Medicines , Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100050 , China.
authors: Ting
authors: T
authors: Gong
authors: Li
authors: L
authors: Zheng
authors: Xin
authors: X
authors: Zhen
authors: Hui-Xia
authors: HX
authors: He
authors: Hui-Xin
authors: HX
authors: Zhu
authors: Ping
authors: P
authors: Zhu
mesh_terms: D006999:Hypocreales / Q000378:metabolism*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009828:Oleanolic Acid / Q000737:chemistry / Q000378:metabolism*
chemical_list: D009828:Oleanolic Acid