title: β-Selective mannosylation with a 4,6-silylene-tethered thiomannosyl donor.
abstract: Mannosylations using the new conformationally restricted donor phenyl 2,3-di-O-benzyl-4,6-O-(di-tert-butylsilylene)-1-thio-α-D-mannopyranoside (6) have been found to be β-selective with a variety of activation conditions. The simplest activation conditions were NIS/TfOH, in which case it is proposed that the β-mannoside is formed from β-selective glycosylation of the oxocarbenium ion 25 in a B(2,5) conformation.
authors: Department of Chemistry, University of Copenhagen , Universitetsparken 5, 2100 Copenhagen Ø, Denmark.
authors: Mads
authors: M
authors: Heuckendorff
authors: Jesper
authors: J
authors: Bendix
authors: Christian M
authors: CM
authors: Pedersen
authors: Mikael
authors: M
authors: Bols