title: Statistical study on the incidence of allergic diseases treated with desloratadine and levocetirizine at "Atopia" Allergology Medical Center, Iaşi, Romania.
abstract: Allergies and allergic manifestations are a major health problem in our country and around the world. Epidemiological data have reported an increased incidence of allergic diseases up to 10-30% over the past decades.
  
  
  OBJECTIVE
  To evaluate the incidence of the most common allergic diseases treated with desloratadine or levocetirizine, second-generation antihistamines.
  
  
  METHODS
  For diagnosis and assessment of treatment with the two antihistamines the following tests were performed: allergy skin testing, immunoglobulin E blood levels, evaluation of target organ for allergic reaction (lung function tests, nasal and conjunctival examination, assessment of bronchial inflammation).
  
  
  RESULTS
  We conducted a retrospective study that included 365 patients (64% women and 36% men) diagnosed with different types of allergy in the "Atopia" Allergology Medical Center at Iaşi during the interval August 2012-August 2013. Patients were aged 2 to 90 years (mean age group 35.98 years; 39.55 years for women, and 29.74 years for men).
  
  
  CONCLUSIONS
  The majority of patients were from urban areas (82%). The most common allergic diseases in the study group were: urticaria (21%), allergic rhinoconjunctivitis (14%), allergic bronchitis (14%) and allergic asthma (12%).
authors: University of Medicine and Pharmacy Grigore T. Popa-Iasi, Faculty of Pharmacy.
authors: Ioana-Cezara
authors: IC
authors: Grigoriu
authors: Allergology Medical Center Atopia-lasi.
authors: Georgeta
authors: G
authors: Siniţchi
authors: University of Medicine and Pharmacy Grigore T. Popa-Iasi, Faculty of Pharmacy.
authors: Luminiţa
authors: L
authors: Agoroaei
authors: University of Medicine and Pharmacy Grigore T. Popa-Iasi, Faculty of Pharmacy.
authors: Anca-Monica
authors: AM
authors: Strugaru
authors: University of Medicine and Pharmacy Grigore T. Popa-Iasi, Faculty of Pharmacy.
authors: Elena
authors: E
authors: Butnaru
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000188:drug therapy; D015415:Biomarkers / Q000097:blood; D017332:Cetirizine / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003233:Conjunctivitis, Allergic / Q000188:drug therapy; D005260:Female; D039563:Histamine H1 Antagonists, Non-Sedating / Q000627:therapeutic use*; D006801:Humans; D006967:Hypersensitivity / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D007073:Immunoglobulin E / Q000097:blood; D015994:Incidence; D017336:Loratadine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D012189:Retrospective Studies; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy; D012383:Romania / Q000453:epidemiology; D012882:Skin Tests; D016896:Treatment Outcome; D014581:Urticaria / Q000188:drug therapy
chemical_list: D015415:Biomarkers; D039563:Histamine H1 Antagonists, Non-Sedating; D007073:Immunoglobulin E; C472067:levocetirizine; D017336:Loratadine; C121345:desloratadine; D017332:Cetirizine