title: Neuroimaging of white matter injury, intraventricular and cerebellar hemorrhage.
abstract: White matter injury and hemorrhage are common findings in extremely preterm infants. Large hemorrhages and extensive cystic lesions are identified with cranial ultrasound. MRI, which is more sensitive, is especially useful in the identification of small intraventricular hemorrhage; cerebellar hemorrhage; punctate lesion in the white matter and cerebellum; and diffuse, noncystic white matter injury. Imaging sequences such as diffusion-weighted, diffusion tensor, and susceptibility weighted imaging may improve recognition and prediction of outcome. These techniques improve understanding of the underlying pathophysiology of white matter injury and its effects on brain development and neurodevelopmental outcome.
authors: Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, KE 04.123.1, PO Box 85090, Utrecht 3508 AB, The Netherlands.
authors: Manon J N L
authors: MJ
authors: Benders
authors: Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, KE 04.123.1, PO Box 85090, Utrecht 3508 AB, The Netherlands.
authors: Karina J
authors: KJ
authors: Kersbergen
authors: Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, KE 04.123.1, PO Box 85090, Utrecht 3508 AB, The Netherlands. Electronic address: l.s.devries@umcutrecht.nl.
authors: Linda S
authors: LS
authors: de Vries
mesh_terms: D002526:Cerebellar Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000473:pathology*; D002552:Cerebral Ventricles / Q000000981:diagnostic imaging / Q000473:pathology*; D004453:Echoencephalography / Q000379:methods; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D020300:Intracranial Hemorrhages / Q000000981:diagnostic imaging / Q000473:pathology; D007969:Leukomalacia, Periventricular / Q000000981:diagnostic imaging / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods; D009413:Nerve Fibers, Myelinated / Q000000981:diagnostic imaging / Q000473:pathology*; D059906:Neuroimaging / Q000379:methods*
keywords: Cerebellar hemorrhage; IVH; Imaging; MRI; PWML; White matter injury; cPVL