title: Biolog Phenotype Microarrays for phenotypic characterization of microbial cells.
abstract: Biolog Phenotype MicroArrays for microorganisms provide a high-throughput method for the global analysis of microbial growth phenotypes. Using a colorimetric reaction that is indicative of respiration, these microplate assays measure the response of an individual strain or microbial community to a large and diverse range of nutrients and chemicals. Phenotype MicroArrays have been used to study gene function and to improve genome annotation in single microorganisms and for physiological profiling of bacterial communities. The microplate system can be used to obtain a comprehensive overview of metabolic capability, or it can be tailored, through the use of subsets of plates, to address specific research needs.
authors: Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW, Australia.
authors: Amanda M
authors: AM
authors: Mackie
authors: Karl A
authors: KA
authors: Hassan
authors: Ian T
authors: IT
authors: Paulsen
authors: Sasha G
authors: SG
authors: Tetu
mesh_terms: D001681:Biological Assay / Q000379:methods*; D002244:Carbon / Q000378:metabolism; D009584:Nitrogen / Q000378:metabolism; D010641:Phenotype; D010758:Phosphorus / Q000378:metabolism; D013455:Sulfur / Q000378:metabolism
chemical_list: D010758:Phosphorus; D013455:Sulfur; D002244:Carbon; D009584:Nitrogen