title: Comprehensive characterization of chitosan/PEO/levan ternary blend films.
abstract: Ternary blend films of chitosan, PEO (300,000) and levan were prepared by solution casting method and their phase behavior, miscibility, thermal and mechanical properties as well as their surface energy and morphology were characterized by different techniques. FT-IR analyses of blend films indicated intermolecular hydrogen bonding between blend components. Thermal and XRD analysis showed that chitosan and levan suppressed the crystallinity of PEO up to nearly 25% of PEO content in the blend, which resulted in more amorphous film structures at higher PEO/(chitosan+levan) ratios. At more than 30% of PEO concentration, contact angle (CA) measurements showed a surface enrichment of PEO whereas at lower PEO concentrations, chitosan and levan were enriched on the surfaces leading to more amorphous and homogenous surfaces. This result was further confirmed by atomic force microscopy (AFM) images. Cell proliferation and viability assay established the high biocompatibility of the blend films.
authors: Marmara University, Department of Chemical Engineering, Kadikoy, 34722 Istanbul, Turkey.
authors: Muge Sennaroglu
authors: MS
authors: Bostan
authors: Marmara University, Department of Bioengineering, Kadikoy, 34722 Istanbul, Turkey.
authors: Esra Cansever
authors: EC
authors: Mutlu
authors: Marmara University, Department of Bioengineering, Kadikoy, 34722 Istanbul, Turkey.
authors: Hande
authors: H
authors: Kazak
authors: Marmara University, Department of Environmental Engineering, Kadikoy, 34722 Istanbul, Turkey.
authors: S
authors: S
authors: Sinan Keskin
authors: Marmara University, Department of Bioengineering, Kadikoy, 34722 Istanbul, Turkey. Electronic address: ebru.toksoy@marmara.edu.tr.
authors: Ebru Toksoy
authors: ET
authors: Oner
authors: Marmara University, Department of Chemical Engineering, Kadikoy, 34722 Istanbul, Turkey; TUBITAK-UME, Chemistry Group Laboratories, PO Box 54, 41471 Gebze, Kocaeli, Turkey. Electronic address: mehmet.eroglu@marmara.edu.tr.
authors: Mehmet S
authors: MS
authors: Eroglu
mesh_terms: D001672:Biocompatible Materials; D002152:Calorimetry, Differential Scanning; D048271:Chitosan / Q000737:chemistry*; D005630:Fructans / Q000737:chemistry*; D006860:Hydrogen Bonding; D018625:Microscopy, Atomic Force; D011092:Polyethylene Glycols / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013818:Thermogravimetry; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D005630:Fructans; D011092:Polyethylene Glycols; D048271:Chitosan; C072599:levan
keywords: Blend film; Chitosan; Exopolysacharide; Levan; Poly(ethylene oxide)