title: Penicilliosis marneffei complicated with interstitial pneumonia.
abstract: A 71-year-old man with interstitial pneumonia was hospitalized due to a pulmonary infection. He had been living in Thailand and had returned to Japan three months earlier. Antibiotic therapy initially cleared the infection; however, the patient's condition relapsed. Pseudomonas aeruginosa and Penicillium sp. were both detected in sputum and bronchial lavage fluid cultures and Penicillium sp. was identified to be P. marneffei. The infiltration observed on chest radiographs improved following treatment with itraconazole and tazobactam/piperacillin, and no relapse occurred. We herein report the first case of a non-HIV patient with P. marneffei infection in Japan.
authors: Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
authors: Haruhiko
authors: H
authors: Furusawa
authors: Yasunari
authors: Y
authors: Miyazaki
authors: Shiro
authors: S
authors: Sonoda
authors: Kimitake
authors: K
authors: Tsuchiya
authors: Takashi
authors: T
authors: Yaguchi
authors: Katsuhiko
authors: K
authors: Kamei
authors: Naohiko
authors: N
authors: Inase
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D007564:Japan; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*; D017563:Lung Diseases, Interstitial / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D010397:Penicillanic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010407:Penicillium / Q000302:isolation & purification / Q000472:pathogenicity*; D010878:Piperacillin / Q000627:therapeutic use; D000077725:Piperacillin, Tazobactam Drug Combination; D013785:Thailand / Q000208:ethnology
chemical_list: D000935:Antifungal Agents; D000077725:Piperacillin, Tazobactam Drug Combination; D017964:Itraconazole; D010397:Penicillanic Acid; D010878:Piperacillin