title: Lung cancer in women: a single institution experience with 50 patients.
abstract: BACKGROUND
  Lung cancer is the most common cause of cancer-related death worldwide. The incidence of lung cancer is aproximately 7-8 thousand percent in Turkish women. In this study, we aimed to evaluate the clinical, pathological properties and survival data of female patients with lung cancer who were treated in our center.
  
  
  METHODS
  From 2007 to 2012, 50 women with lung cancer were enrolled. Patient data were evaluated retrospectively.
  
  
  RESULTS
  The median age was 61 (40-81). Forty patients (80%) were diagnosed with non small cell lung cancer (NSCLC), 10 patients (20%) were small cell carcinoma (SCC). Twelve (24%) patients were smokers and 13 of 16 non-smokers had a history of exposure to asbestos. The most common histologic subtype was adenocarcinoma (46%) and this accounted for 71% in patients with exposure to asbestos. The most common initial Eastern Cooperative Oncology Group (ECOG) performance score was 1 (24 patients, 48%) and initial stage was IV (25 patients, 50%) in the study group. During the median 15 months (1-96 months) followup period: 1 year overall survival (OS) was 68%, 2year overall survival was 36% and the median survival time was 19 months. According to univariate analysis, poor ECOG performance status, advanced stage, anemia and weight loss at time of diagnosis were negative prognostic factors. However, adenocarcinoma sub-type was a positive prognostic factor.
  
  
  CONCLUSIONS
  In this study NSCLC sub-type, poor ECOG performance score, advanced stage, anemia and weight loss were prognostic factors in Turkish women with lung cancer.
authors: Departments of Medical Oncology, University of Cumhuriyet, SIVAS, Turkey E-mail : nalanbabacan@gmail.com.
authors: Nalan Akgul
authors: NA
authors: Babacan
authors: Birsen
authors: B
authors: Yucel
authors: Saadettin
authors: S
authors: Kilickap
authors: Mehmet Metin
authors: MM
authors: Seker
authors: Turgut
authors: T
authors: Kacan
authors: Ilknur Koc
authors: IK
authors: Olcas
authors: Ayfer Ay
authors: AA
authors: Eren
authors: Hatice
authors: H
authors: Odabas
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001194:Asbestos / Q000009:adverse effects; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D005260:Female; D006304:Health Status; D006801:Humans; D053208:Kaplan-Meier Estimate; D008175:Lung Neoplasms / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D055752:Small Cell Lung Carcinoma / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D012907:Smoking / Q000009:adverse effects; D015996:Survival Rate; D014421:Turkey
chemical_list: D001194:Asbestos