title: [Sero-epidemiological investigation on hepatitis B among permanent residents in Shenzhen area].
abstract: OBJECTIVE
  To understand the infection status and epidemiological features of HBV in permanent residents of Shenzhen city.
  
  
  METHODS
  A multi-stage stratified random sampling method was performed for questionnaire survey to permanently-registered residents of 1-59 years old in Luohu and Baoan district of Shenzhen in 2010, and blood samples of the subjects were collected. Hepatitis B virus-related surface antigen (HBsAg) and hepatitis B virus surface antibody (anti-HBs) were detected with ELISA.
  
  
  RESULTS
  The total 3771 studied population showed 252 HBsAg positive and 2712 anti-HBs positive residents with the standardization prevalence as 9.73% and 72.83% , respectively. The difference of the prevalence of HBsAg and anti-HBs between males and females were not statistically significant (P > 0.05). The prevalence of HBsAg was reduced with increasing age. The differences of the prevalence of HBsAg between Shenzhen permanent registered and non-permanent registered population were not significant, but the prevalence of anti-HBs in Permanent registered residents (78.32%) was higher than in non-permanent (66.03%, χ(2) = 41.613, P < 0.001). The prevalence of HBsAg was significantly different in various occupational and educational levels. Peasants had the highest prevalence (24.13%) and medical workers had the highest prevalence of anti-HBs (89.10% ). People with junior high school education had the highest prevalence of HBsAg (12.76%) and the lowest of anti-HBs (62.45%). Population with high-level education had the highest prevalence of anti-HBs(81.00% average). The prevalence of HBsAg was over 10% in people who were born in Shenzhen and Guangdong province, and the anti-HBs was the highest in Shenzhen population with the prevalence as 74.48% and 76.47% , respectively.
  
  
  CONCLUSIONS
  In the Shenzhen resident population, the overall prevalence of HBV was lower than the average level of Guangdong province, but higher than the national wide.
authors: Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China. Email: cjinquan@szcdc.net.
authors: Jin-quan
authors: JQ
authors: Cheng
authors: Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
authors: Han-wu
authors: HW
authors: Ma
authors: Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
authors: Xu
authors: X
authors: Xie
authors: Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
authors: Yan
authors: Y
authors: Lu
authors: Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
authors: Yan-biao
authors: YB
authors: Zhang
authors: Health and Population-Family, Planning Bureau of Luohu.
authors: Shu-xian
authors: SX
authors: Dong
authors: Health and Population-Family, Planning Bureau of Luohu.
authors: Ting-zhe
authors: TZ
authors: Wang
authors: Baoan Center for Disease Control and Prevention, Shenzhen.
authors: Yi-min
authors: YM
authors: Liu
authors: College of Public Health, Zhongshan University.
authors: Wen-hua
authors: WH
authors: Ling
authors: College of Public Health, Zhongshan University.
authors: Yuan-tao
authors: YT
authors: Hao
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006509:Hepatitis B / Q000097:blood* / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D011795:Surveys and Questionnaires