title: Surfactant protein D in chornic obstructive pulmonary disease (COPD).
abstract: In the recent years, a large number of potential biomarkers for Chronic Obstructive Pulmonary Disease (COPD) have been described. One of the important biomarkers is Surfactant Protein D (SPD) since serum SPD levels have been associated with lung function or health status in patients with severe COPD. Several interesting evidences of the protein and gene polymorphisms have been described. The present review highlights the current literature, recent patents and, future prospects of this important collection.
authors: Dolores
authors: D
authors: Moreno
authors: Alexis
authors: A
authors: Garcia
authors: Diego
authors: D
authors: Lema
authors: Catedra de Patologia General y Fisiopatologia, Facultad de Medicina, Universidad Central de Venezuela, Caracas 1050-A, Venezuela. moreno.d1@gmail.com.
authors: Juan B
authors: JB
authors: De Sanctis
mesh_terms: D015415:Biomarkers / Q000097:blood; D006801:Humans; D008954:Models, Biological; D010330:Patents as Topic; D011110:Polymorphism, Genetic; D029424:Pulmonary Disease, Chronic Obstructive / Q000097:blood* / Q000188:drug therapy* / Q000235:genetics / Q000503:physiopathology; D037663:Pulmonary Surfactant-Associated Protein D / Q000097:blood* / Q000235:genetics / Q000502:physiology / Q000627:therapeutic use*
chemical_list: D015415:Biomarkers; D037663:Pulmonary Surfactant-Associated Protein D