title: Antimicrobial activity of thin solid films of silver doped hydroxyapatite prepared by sol-gel method.
abstract: In this work, the preparation and characterization of silver doped hydroxyapatite thin films were reported and their antimicrobial activity was characterized. Silver doped hydroxyapatite (Ag:HAp) thin films coatings substrate was prepared on commercially pure Si disks by sol-gel method. The silver doped hydroxyapatite thin films were characterized by various techniques such as Scanning electron microscopy (SEM) with energy Dispersive X-ray attachment (X-EDS), Fourier transform infrared spectroscopy (FT-IR), and glow discharge optical emission spectroscopy (GDOES). These techniques have permitted the structural and chemical characterisation of the silver doped hydroxyapatite thin films. The antimicrobial effect of the Ag:HAp thin films on Escherichia coli and Staphylococcus aureus bacteria was then investigated. This is the first study on the antimicrobial effect of Ag:HAp thin films obtained by sol-gel method. The results of this study have shown that the Ag:HAp thin films with x(Ag) = 0.5 are effective against E. coli and S. aureus after 24 h.
authors: National Institute of Materials Physics, P.O. Box MG 07, Magurele, Romania.
authors: Simona Liliana
authors: SL
authors: Iconaru
authors: Horiba Jobin Yvon S.A., 16-18 rue du Canal, 91165 Longjumeau Cedex, France.
authors: Patrick
authors: P
authors: Chapon
authors: Universite Bordeaux, EA 4592 Géoressources & Environnement, ENSEGID, 1 allée F. Daguin, 33607 Pessac Cedex, France.
authors: Philippe
authors: P
authors: Le Coustumer
authors: National Institute of Materials Physics, P.O. Box MG 07, Magurele, Romania.
authors: Daniela
authors: D
authors: Predoi
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology*; D017886:Durapatite / Q000737:chemistry*; D005782:Gels / Q000737:chemistry* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D008855:Microscopy, Electron, Scanning; D012834:Silver / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D005782:Gels; D012834:Silver; D017886:Durapatite