title: Functionalization of an sp(3) C-H bond via a redox-neutral domino reaction: diastereoselective synthesis of hexahydropyrrolo[2,1-b]oxazoles.
abstract: A diastereoselective synthesis of pyrrolidinooxazolidines was achieved by a metal-free, base-promoted reaction of pyrrolidine and aromatic aldehydes under microwave irradiation. The rare functionalization of an sp(3) C-H bond probably results from an in situ generated azomethine ylide that undergoes cycloaddition with aldehydes.
authors: Department of Chemistry, Visva-Bharati, Santiniketan-731235, India. alakananda.hajra@visva-bharati.ac.in.
authors: Matiur
authors: M
authors: Rahman
authors: Avik Kumar
authors: AK
authors: Bagdi
authors: Subhajit
authors: S
authors: Mishra
authors: Alakananda
authors: A
authors: Hajra
mesh_terms: D002244:Carbon / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D008872:Microwaves; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D019347:Potassium Acetate / Q000737:chemistry; D013237:Stereoisomerism; D014050:Toluene / Q000737:chemistry
chemical_list: D010080:Oxazoles; D014050:Toluene; D002244:Carbon; D006859:Hydrogen; D019347:Potassium Acetate