title: Allergic contact dermatitis due to nickel: descriptive study in a tertiary hospital, 2000-2010.
abstract: OBJECTIVE
  The aim of this study based on the records of the dermatology department of a tertiary referral hospital was to describe patients treated for allergic contact dermatitis induced by nickel between 2000 and 2010.
  
  
  METHODS
  From records of the skin allergy section of the dermatology department we extracted and analyzed information for patients who underwent patch testing with the standard series of the Spanish Contact Dermatitis Research Group (GEIDAC), which includes a patch with 5% nickel sulfate in petroleum jelly. The possibility that nickel release from various objects might have triggered the patient's dermatitis was assessed with the dimethylglyoxime spot test, which reveals a reddish precipitate if the metal is present.
  
  
  RESULTS
  A total of 3,404 patients underwent GEIDAC patch testing during the study period; 24.2% had positive reactions to the patch containing 5% nickel sulfate in petroleum jelly. However, the contact dermatitis could be attributed to nickel in only 57 of the 824 patients (6.9%) who showed sensitization to nickel.
  
  
  CONCLUSIONS
  Patch-test evidence of sensitization was found to be clinically relevant in only a small percentage of patients. We emphasize the usefulness of the dimethylglyoxime test to help establish the relevance of a positive nickel patch test. This test is even useful for identifying the specific object responsible for a patient's dermatitis.
authors: Servicio de Dermatología, Consorcio Hospital General Universitario de Valencia, Valencia, España. Electronic address: anagrabasco@gmail.com.
authors: A E
authors: AE
authors: García-Rabasco
authors: Servicio de Dermatología, Consorcio Hospital General Universitario de Valencia, Valencia, España.
authors: V
authors: V
authors: Zaragozá-Ninet
authors: Servicio de Dermatología, Consorcio Hospital General Universitario de Valencia, Valencia, España.
authors: R
authors: R
authors: García-Ruíz
authors: Servicio de Dermatología, Consorcio Hospital General Universitario de Valencia, Valencia, España.
authors: J
authors: J
authors: de la Cuadra-Oyanguren
mesh_terms: D000293:Adolescent; D000328:Adult; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects*; D010091:Oximes; D010328:Patch Tests; D012189:Retrospective Studies; D062606:Tertiary Care Centers; D013997:Time Factors; D055815:Young Adult
chemical_list: D010091:Oximes; C013501:dimethylglyoxime; C029938:nickel sulfate; D009532:Nickel
keywords: Contact dermatitis; Dimethylglyoxime test; Eccema de contacto; Nickel; Níquel; Relevance; Relevancia; Test de dimetilglioxima