title: Hemolytic uremic syndrome in a 65-Year-old male linked to a very unusual type of stx2e- and eae-harboring O51:H49 shiga toxin-producing Escherichia coli.
abstract: We report on a 65-year-old male patient with a Shiga toxin-producing Escherichia coli O51:H49 gastrointestinal infection and sepsis associated with hemolytic uremic syndrome (HUS) with a fatal outcome. The strains isolated harbored stx2e and eae, a very unusual and new virulence profile for an HUS-associated enterohemorrhagic E. coli.
authors: Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland.
authors: Dominique
authors: D
authors: Fasel
authors: Alexander
authors: A
authors: Mellmann
authors: Nicole
authors: N
authors: Cernela
authors: Herbert
authors: H
authors: Hächler
authors: Angelika
authors: A
authors: Fruth
authors: Nina
authors: N
authors: Khanna
authors: Adrian
authors: A
authors: Egli
authors: Christiane
authors: C
authors: Beckmann
authors: Hans H
authors: HH
authors: Hirsch
authors: Daniel
authors: D
authors: Goldenberger
authors: Roger
authors: R
authors: Stephan
mesh_terms: D018829:Adhesins, Bacterial / Q000235:genetics*; D000368:Aged; D004927:Escherichia coli Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D029968:Escherichia coli Proteins / Q000235:genetics*; D017809:Fatal Outcome; D005759:Gastroenteritis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D018805:Sepsis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D065288:Serogroup; D022641:Shiga Toxin 2 / Q000235:genetics*; D054323:Shiga-Toxigenic Escherichia coli / Q000235:genetics / Q000302:isolation & purification*; D037521:Virulence Factors / Q000235:genetics
chemical_list: D018829:Adhesins, Bacterial; D029968:Escherichia coli Proteins; D022641:Shiga Toxin 2; D037521:Virulence Factors; C073819:eaeA protein, E coli