title: Assessing the association between oral hygiene and preterm birth by quantitative light-induced fluorescence.
abstract: The aim of this study was to investigate the purported link between oral hygiene and preterm birth by using image analysis tools to quantify dental plaque biofilm. Volunteers (n = 91) attending an antenatal clinic were identified as those considered to be "at high risk" of preterm delivery (i.e., a previous history of idiopathic preterm delivery, case group) or those who were not considered to be at risk (control group). The women had images of their anterior teeth captured using quantitative light-induced fluorescence (QLF). These images were analysed to calculate the amount of red fluorescent plaque (ΔR%) and percentage of plaque coverage. QLF showed little difference in ΔR% between the two groups, 65.00% case versus 68.70% control, whereas there was 19.29% difference with regard to the mean plaque coverage, 25.50% case versus 20.58% control. A logistic regression model showed a significant association between plaque coverage and case/control status (P = 0.031), controlling for other potential predictor variables, namely, smoking status, maternal age, and body mass index (BMI).
authors: Department of Health Services Research, University of Liverpool, Liverpool L69 3GN, UK ; School of Dentistry, University of Liverpool, Liverpool L3 5PS, UK.
authors: Christopher K
authors: CK
authors: Hope
authors: Department of Health Services Research, University of Liverpool, Liverpool L69 3GN, UK ; School of Dentistry, University of Liverpool, Liverpool L3 5PS, UK.
authors: Qian
authors: Q
authors: Wang
authors: School of Dentistry, University of Liverpool, Liverpool L3 5PS, UK ; Department of Biostatistics, University of Liverpool, Liverpool L69 3BX, UK.
authors: Girvan
authors: G
authors: Burnside
authors: Department of Health Services Research, University of Liverpool, Liverpool L69 3GN, UK ; School of Dentistry, University of Liverpool, Liverpool L3 5PS, UK.
authors: Adejumoke A
authors: AA
authors: Adeyemi
authors: Department of Women's and Children's Health, University of Liverpool, Liverpool L8 7SS, UK ; Division of Reproductive Health, The University of Warwick, Coventry CV4 7AL, UK.
authors: Siobhan
authors: S
authors: Quenby
authors: Department of Health Services Research, University of Liverpool, Liverpool L69 3GN, UK ; School of Dentistry, University of Liverpool, Liverpool L3 5PS, UK.
authors: Philip W
authors: PW
authors: Smith
authors: Department of Health Services Research, University of Liverpool, Liverpool L69 3GN, UK ; School of Dentistry, University of Liverpool, Liverpool L3 5PS, UK.
authors: Susan M
authors: SM
authors: Higham
authors: Department of Women's and Children's Health, University of Liverpool, Liverpool L8 7SS, UK ; Centre for Women's Health, The University of Manchester, Manchester M13 9WL, UK.
authors: Melissa
authors: M
authors: Whitworth
mesh_terms: D000328:Adult; D018441:Biofilms; D016022:Case-Control Studies; D003773:Dental Plaque / Q000382:microbiology; D005260:Female; D005453:Fluorescence; D006801:Humans; D007231:Infant, Newborn; D008875:Middle Aged; D009910:Oral Hygiene; D011247:Pregnancy; D047928:Premature Birth / Q000209:etiology*; D012307:Risk Factors; D055815:Young Adult