title: Comparison of complication rates between umbilical and peripherally inserted central venous catheters in newborns.
abstract: OBJECTIVE
  To compare the complication rates between umbilical central venous catheters and peripherally inserted central venous catheters in newborns and to investigate whether other variables might increase complication rates.
  
  
  METHODS
  A retrospective observational study.
  
  
  METHODS
  A Level III neonatal intensive care unit (NICU).
  
  
  METHODS
  Newborns (gestational age 24-42 weeks).
  
  
  METHODS
  All central venous catheter-related complications were retrospectively analyzed in newborns. The differences in survival rates between the two types of central venous catheters were evaluated using a Kaplan-Meier survival analysis with removal because of complications as the event of interest.
  
  
  RESULTS
  In total, 140 umbilical venous catheters and 63 peripherally inserted central catheters were included. There were no significant differences in removals due to complications between the two catheters. The central line-associated bloodstream infections had the highest complication incidence, followed by obstruction, dislocation, leakage, and extravasation. There were no influences of gestational age, birth weight, and the use of subsequent catheters on the complication incidence.
  
  
  CONCLUSIONS
  A high complication incidence resulted in removal of the catheters, but it was not significantly different between the two catheters. The prevention of complications should be an important goal in the daily care of infants in the NICU.
authors: Inge Johanna Jacoba
authors: IJ
authors: Arnts
authors: Lauren Maria
authors: LM
authors: Bullens
authors: Joannes Martinus Maria
authors: JM
authors: Groenewoud
authors: Kian Djien
authors: KD
authors: Liem
mesh_terms: D001724:Birth Weight; D055499:Catheter-Related Infections / Q000175:diagnosis / Q000453:epidemiology*; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000401:mortality; D002406:Catheterization, Peripheral / Q000009:adverse effects* / Q000401:mortality; D062905:Central Venous Catheters / Q000009:adverse effects; D015331:Cohort Studies; D016001:Confidence Intervals; D020878:Device Removal / Q000706:statistics & numerical data; D004869:Equipment Safety; D005260:Female; D005500:Follow-Up Studies; D005865:Gestational Age; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007234:Infant, Premature; D007363:Intensive Care Units, Neonatal; D053208:Kaplan-Meier Estimate; D008297:Male; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D018570:Risk Assessment; D015996:Survival Rate; D062606:Tertiary Care Centers; D013997:Time Factors; D014471:Umbilical Veins
keywords: Central venous catheter; central line-associated bloodstream infection; complication; newborn; nursing; sepsis