title: Anti-stokes fluorescent probe with incoherent excitation.
abstract: Although inorganic anti-Stokes fluorescent probes have long been developed, the operational mode of today's most advanced examples still involves the harsh requirement of coherent laser excitation, which often yields unexpected light disturbance or even photon-induced deterioration during optical imaging. Here, we demonstrate an efficient anti-Stokes fluorescent probe with incoherent excitation. We show that the probe can be operated under light-emitting diode excitation and provides tunable anti-Stokes energy shift and decay kinetics, which allow for rapid and deep tissue imaging over a very large area with negligible photodestruction. Charging of the probe can be achieved by either X-rays or ultraviolet-visible light irradiation, which enables multiplexed detection and function integration with standard X-ray medical imaging devices.
authors: State Key Laboratory of Luminescent Materials and Devices, Institute of Optical Communication Materials, School of Materials Science and Technology, South China University of Technology, Guangzhou 510640, China.
authors: Yang
authors: Y
authors: Li
authors: State Key Laboratory of Luminescent Materials and Devices, Institute of Optical Communication Materials, School of Materials Science and Technology, South China University of Technology, Guangzhou 510640, China.
authors: Shifeng
authors: S
authors: Zhou
authors: State Key Laboratory of Luminescent Materials and Devices, Institute of Optical Communication Materials, School of Materials Science and Technology, South China University of Technology, Guangzhou 510640, China.
authors: Guoping
authors: G
authors: Dong
authors: State Key Laboratory of Luminescent Materials and Devices, Institute of Optical Communication Materials, School of Materials Science and Technology, South China University of Technology, Guangzhou 510640, China.
authors: Mingying
authors: M
authors: Peng
authors: Otto Schott Institute, University of Jena, Jena07743, Germany.
authors: Lothar
authors: L
authors: Wondraczek
authors: State Key Laboratory of Luminescent Materials and Devices, Institute of Optical Communication Materials, School of Materials Science and Technology, South China University of Technology, Guangzhou 510640, China.
authors: Jianrong
authors: J
authors: Qiu
mesh_terms: D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D056831:Coordination Complexes / Q000737:chemistry / Q000633:toxicity; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000633:toxicity; D007700:Kinetics; D007834:Lasers; D008027:Light; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000187:drug effects; D061848:Optical Imaging / Q000295:instrumentation / Q000379:methods*; D014466:Ultraviolet Rays
chemical_list: D056831:Coordination Complexes; D005456:Fluorescent Dyes