title: Results of treatment of acute myeloid leukemia in central part of Iran.
abstract: BACKGROUND
  Acute myeloid leukemia (AML) is the most common type of leukemia. In this study, outcome of intensive chemotherapy in patients treated in a large urban public university hospital in a developing country was investigated.
  
  
  METHODS
  The records of all patients treated for AML with 3 + 7 protocol from 2002 to 2010 were analyzed.
  
  
  RESULTS
  Among 95 patients, 34 (35.8%) were female and 61 (64.2%) were male patients. Patients' median age was 37 years, ranging 15-68 years. Complete remission (CR) was observed in 56 (58.9%) of patients treated with this protocol. Median overall survival was 13 months (95% CI: 8.8-17.1 months). The 1-year AML survival rate was 51%, and 2-year survival rate was 26%.
  
  
  CONCLUSIONS
  Our study shows that in our center in Iran, CR rates and median overall survival rates after induction chemotherapy are less than developed countries.
authors: Department of Internal Medicine and Division of Hematology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Farzaneh
authors: F
authors: Ashrafi
authors: School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Razieh
authors: R
authors: Shahnazari
authors: Department of Internal Medicine and Division of Hematology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Mojgan Alam
authors: MA
authors: Samimi
authors: Department of Internal Medicine and Division of Hematology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Valliollah
authors: V
authors: Mehrzad
keywords: Acute myeloid leukemia; remission; survival; treatment