title: Lower thoracic degenerative spondylithesis with concomitant lumbar spondylosis.
abstract: OBJECTIVE
  Degenerative spondylolisthesis of the spine is less common in the lower thoracic region than in the lumbar and cervical regions. However, lower thoracic degenerative spondylolisthesis may develop secondary to intervertebral disc degeneration. Most of our patients are found to have concomitant lumbar spondylosis. By retrospective review of our cases, current diagnosis and treatments for this rare disease were discussed.
  
  
  METHODS
  We present a series of 5 patients who experienced low back pain, progressive numbness, weakness and even paraparesis. Initially, all of them were diagnosed with lumbar spondylosis at other clinics, and 1 patient had even received prior decompressive lumbar surgery. However, their symptoms continued to progress, even after conservative treatments or lumbar surgeries. These patients also showed wide-based gait, increased deep tendon reflex (DTR), and urinary difficulty. All these clinical presentations could not be explained solely by lumbar spondylosis. Thoracolumbar spinal magnetic resonance imaging (MRI), neurophysiologic studies such as motor evoked potential (MEP) or somatosensory evoked potential (SSEP), and dynamic thoracolumbar lateral radiography were performed, and a final diagnosis of lower thoracic degenerative spondylolisthesis was made.
  
  
  RESULTS
  Bilateral facet effusions, shown by hyperintense signals in T2 MRI sequence, were observed in all patients. Neurophysiologic studies revealed conduction defect of either MEP or SSEP. One patient refused surgical management because of personal reasons. However, with the use of thoracolumbar orthosis, his symptoms/signs stabilized, although partial lower leg myelopathy was present. The other patients received surgical decompression in association with fixation/fusion procedures performed for managing the thoracolumbar lesions. Three patients became symptom-free, whereas in 1 patient, paralysis set in before the operation; this patient was able to walk with assistance 6 months after surgical decompression. The average Nurick scale score improved from 3.75 before the operation to 2 after the operation.
  
  
  CONCLUSIONS
  Lower thoracic degenerative spondylolisthesis is a rare disease, which may occur concomitantly with lumbar spondylosis and confuse clinicians. Diagnosis should be made properly, especially because symptoms/signs cannot be explained purely on the basis of the available images. Micromotion due to facet joint laxity and disc degeneration was believed as the cause of progressive myelopathy. Posterior decompression with fixation/fusion procedure was appropriate for the treatment of thoracic spondylolisthesis secondary to thoracic disc degeneration.
authors: Department of Neurosurgery, Chang Gung Memorial Hospital, Chang Gung University and Medical College, Tao-Yuan, Taiwan, ROC.
authors: Po-Chuan
authors: PC
authors: Hsieh
authors: Department of Neurosurgery, Chang Gung Memorial Hospital, Chang Gung University and Medical College, Tao-Yuan, Taiwan, ROC.
authors: Shih-Tseng
authors: ST
authors: Lee
authors: Department of Neurosurgery, Chang Gung Memorial Hospital, Chang Gung University and Medical College, Tao-Yuan, Taiwan, ROC. Electronic address: PoChuan.Hsieh@gmail.com.
authors: Jyi-Feng
authors: JF
authors: Chen
mesh_terms: D000368:Aged; D001863:Bone Screws; D019299:Decompression, Surgical; D019054:Evoked Potentials, Motor; D005073:Evoked Potentials, Somatosensory; D005260:Female; D020233:Gait Disorders, Neurologic / Q000209:etiology; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000150:complications* / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D007796:Laminectomy; D017116:Low Back Pain / Q000209:etiology; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology; D009460:Neurologic Examination; D020335:Paraparesis / Q000209:etiology; D012189:Retrospective Studies; D013131:Spine / Q000473:pathology; D013168:Spondylolisthesis / Q000150:complications* / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D055009:Spondylosis / Q000150:complications* / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D013904:Thoracic Vertebrae
keywords: Degenerative spondylolisthesis; Lower thoracic spine; Lumbar spondylosis; Myelopathy