title: Serological and molecular diagnosis of hepatitis delta virus infection: results of a French national quality control study.
abstract: A French national quality control study for the serological and molecular diagnosis of hepatitis delta virus (HDV) was organized. Total HDV antibodies were properly detected by all laboratories; 8/14 laboratories failed to detect low titers of IgM, and 6/11 failed to quantify and/or underestimated the RNA viral load in several samples. These discrepancies are likely related to the molecular diversity of HDV.
authors: Laboratoire de Bactériologie, Virologie, Hygiène, Hôpitaux Universitaires de Paris Seine-Saint-Denis, Site Avicenne, Bobigny, and Assistance Publique-Hôpitaux de Paris, Paris, France.
authors: Ségolène
authors: S
authors: Brichler
authors: Frédéric
authors: F
authors: Le Gal
authors: Fernando
authors: F
authors: Neri-Pinto
authors: Wael
authors: W
authors: Mansour
authors: Dominique
authors: D
authors: Roulot
authors: Syria
authors: S
authors: Laperche
authors: Emmanuel
authors: E
authors: Gordien
mesh_terms: D006508:Hepatitis Antibodies / Q000276:immunology; D003699:Hepatitis D / Q000175:diagnosis* / Q000276:immunology* / Q000821:virology; D003698:Hepatitis Delta Virus / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D057089:Pathology, Molecular / Q000379:methods; D011786:Quality Control; D012698:Serologic Tests / Q000379:methods; D019562:Viral Load / Q000276:immunology
chemical_list: D006508:Hepatitis Antibodies; D007075:Immunoglobulin M