title: Metastasizing "benign" pleomorphic salivary adenoma: a dramatic case-report and literature review.
abstract: Pleomorphic salivary adenomas are the most common benign neoplasms affecting the salivary glands. Very occasionally however, metastatic lesions are identified in patients with a history of PSA, which, on detailed pathological evaluation, are found to exhibit all the histological hallmarks of the preceding benign lesions. Diagnosis of benign metastasizing pleomorphic adenoma of the salivary gland is extremely rare and still under debate. We present the first case-report in literature of multiple metachronous nasal cavity, scalp and encephalic metastases of a pleomorphic adenoma of the parotid gland in a young girl.
authors: Maxillofacial Surgery Unit, Alma Mater Studiorum University of Bologna, Bologna, Italy. Electronic address: achilletarsitano@gmail.com.
authors: Achille
authors: A
authors: Tarsitano
authors: Department of Hematology and Oncology, Section of Pathological Anatomy, Bellaria Hospital, University of Bologna, Bologna, Italy.
authors: Maria Pia
authors: MP
authors: Foschini
authors: ENT Unit, Alma Mater Studiorum University of Bologna, Bologna, Italy.
authors: Paolo
authors: P
authors: Farneti
authors: ENT Unit, Alma Mater Studiorum University of Bologna, Bologna, Italy.
authors: Ernesto
authors: E
authors: Pasquini
authors: Maxillofacial Surgery Unit, Alma Mater Studiorum University of Bologna, Bologna, Italy.
authors: Claudio
authors: C
authors: Marchetti
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000473:pathology; D006801:Humans; D009296:Nasal Cavity / Q000473:pathology; D015508:Nasal Obstruction / Q000175:diagnosis; D016609:Neoplasms, Second Primary / Q000473:pathology*; D009669:Nose Neoplasms / Q000473:pathology; D010307:Parotid Neoplasms / Q000473:pathology*; D012535:Scalp / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology
keywords: Metastasizing pleomorphic salivary adenoma; Multiple pleomorphic adenomas; Parotid gland tumours