title: Cotton fabric finished with β-cyclodextrin: Inclusion ability toward antimicrobial agent.
abstract: β-Cyclodextrin was grafted onto cotton fabric through crosslinking with butane tetracarboxylic acid in presence of sodium hypophosphite monohydrate as a catalyst. This finished cotton fabric was loaded with the antimicrobial agent octenidine dihydrochloride. β-Cyclodextrin-grafted cotton fabrics, both after loading with octenidine dihydrochloride or before loading (control) were characterized for their antimicrobial activity against two types of bacteria (Gram positive and Gram negative) and two types of fungi, using the Diffusion Disk Method. The antimicrobial cotton fabric was subjected to several washing cycles and the antimicrobial activity was measured after each washing cycle to examine the durability of this antimicrobial finishing against repeated washing. The measurements showed that the finished cotton fabrics retain reasonable deal of their antimicrobial activity, even after 20 washing cycles. This long-lasting antimicrobial activity is attributed to the hosting ability of the cavities present in cyclodextrin moieties, which host the antimicrobial agent molecules and release them gradually.
authors: Petrochemical Research Chair, Chemistry Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. Electronic address: essamya@yahoo.com.
authors: E S
authors: ES
authors: Abdel-Halim
authors: Petrochemical Research Chair, Chemistry Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
authors: Salem S
authors: SS
authors: Al-Deyab
authors: Petrochemical Research Chair, Chemistry Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
authors: Ali Y A
authors: AY
authors: Alfaifi
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D032561:Cotton Fiber; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D013696:Temperature; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D047392:beta-Cyclodextrins; C031215:betadex
keywords: Antimicrobial activity; Cotton fabric; Finishing; β-Cyclodextrin