title: Association Between the Hypertriglyceridemic Waist Phenotype, Prediabetes, and Diabetes Mellitus Among Adults in Puerto Rico.
abstract: This study assessed the association of the hypertriglyceridemic waist (HTGW) phenotype with prediabetes and diabetes (DM) in a group of Hispanics. Analysis of a cross-sectional study of 858 adults residing in Puerto Rico that collected data on blood pressure, biochemical, and anthropometric measurements was performed. HTGW phenotype was defined as elevated triglycerides and elevated waist circumference. Prediabetes was defined as a fasting glucose of 100-125 mg/dL and DM as a fasting glucose ≥126 mg/dL or prior diagnosis. Prevalence of HTGW, prediabetes, and DM was 27.9, 38.0, and 21.6 %, respectively. Subjects with the HTGW phenotype had higher adjusted odds of prediabetes (POR 5.55; 95 % CI 3.38-9.13) and DM (POR 7.28; 95 % CI 3.63-14.63) compared to those without the phenotype. The association for prediabetes was stronger for women than among men. HTGW phenotype was strongly associated with prediabetes and DM, reinforcing the need to further assess its performance as a screening tool to identify at-risk individuals for cardiometabolic conditions.
authors: Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, USA. mvdiaz@schoolph.umass.edu.|Department of Public Health, School of Public Health and Health Sciences, University of Massachusetts, 408 Arnold House, 715N. Pleasant Street, Amherst, MA, 01003-9304, USA. mvdiaz@schoolph.umass.edu.
authors: Mary Vanellys
authors: MV
authors: Díaz-Santana
authors: Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, USA. erick.suarez@upr.edu.
authors: Erick L
authors: EL
authors: Suárez Pérez
authors: Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, USA. ana.ortiz7@upr.edu.
authors: Ana P
authors: AP
authors: Ortiz Martínez
authors: School of Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, USA. drmguzman@onelinkpr.net.
authors: Manuel
authors: M
authors: Guzmán Serrano
authors: Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, USA. cynthia.perez1@upr.edu.
authors: Cynthia M
authors: CM
authors: Pérez Cardona
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001786:Blood Glucose; D001794:Blood Pressure; D001837:Body Weights and Measures; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000208:ethnology*; D005260:Female; D015438:Health Behavior; D006630:Hispanic or Latino / Q000706:statistics & numerical data*; D006801:Humans; D064250:Hypertriglyceridemic Waist / Q000208:ethnology*; D008019:Life Style; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D011236:Prediabetic State / Q000208:ethnology*; D011647:Puerto Rico / Q000453:epidemiology; D012307:Risk Factors; D012737:Sex Factors; D012959:Socioeconomic Factors; D055815:Young Adult
chemical_list: D001786:Blood Glucose
keywords: Diabetes; Hispanics; Hypertriglyceridemic waist phenotype; Prediabetes; Puerto Ricans