title: The deep inspiration breath hold technique using Abches reduces cardiac dose in patients undergoing left-sided breast irradiation.
abstract: OBJECTIVE
  We explored whether the deep inspiration breath hold (DIBH) technique using Abches during left-sided breast irradiation was effective for minimizing the amount of radiation to the heart and lung compared to free breathing (FB).
  
  
  METHODS
  Between February and July 2012, a total of 25 patients with left-sided breast cancer underwent two computed tomography scans each with the DIBH using Abches and using FB after breast-conserving surgery. The scans were retrospectively replanned using standardized criteria for the purpose of this study. The DIBH plans for each patient were compared with FB plans using dosimetric parameters.
  
  
  RESULTS
  All patients were successfully treated with the DIBH technique using Abches. Significant differences were found between the DIBH and FB plans for mean heart dose (2.52 vs. 4.53 Gy), heart V30 (16.48 vs. 45.13 cm(3)), V20 (21.35 vs. 54.55 cm(3)), mean left anterior descending coronary artery (LAD) dose (16.01 vs. 26.26 Gy, all p < 0.001), and maximal dose to 0.2 cm(3) of the LAD (41.65 vs. 47.27 Gy, p = 0.017). The mean left lung dose (7.53 vs. 8.03 Gy, p = 0.073) and lung V20 (14.63% vs. 15.72%, p = 0.060) of DIBH using Abches were not different significantly compared with FB.
  
  
  CONCLUSIONS
  We report that the use of a DIBH technique using Abches in breathing adapted radiotherapy for left-sided breast cancer is easily feasible in daily practice and significantly reduces the radiation doses to the heart and LAD, therefore potentially reducing cardiac risk.
authors: Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
authors: Ha Yoon
authors: HY
authors: Lee
authors: Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
authors: Jee Suk
authors: JS
authors: Chang
authors: Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
authors: Ik Jae
authors: IJ
authors: Lee
authors: Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
authors: Kwangwoo
authors: K
authors: Park
authors: Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
authors: Yong Bae
authors: YB
authors: Kim
authors: Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
authors: Chang Ok
authors: CO
authors: Suh
authors: Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
authors: Jun Won
authors: JW
authors: Kim
authors: Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
authors: Ki Chang
authors: KC
authors: Keum
keywords: Abches; Cardiac toxicity; Deep inspiration breath hold