title: Antibacterial activity of polyacrylonitrile-chitosan electrospun nanofibers.
abstract: Polyacrylonitrile (PAN)-chitosan double-face films and nanofibers were manufactured. PAN and a chitosan salt were dissolved in dimethyl sulfoxide, and then thin-layered on a glass plate or electro-spun followed by coagulation in sodium hydroxide solution. The morphology of the PAN-chitosan double-face films and nanofibers was analyzed by scanning electron microscopy. The thermal behavior and the glass transition temperature of PAN-chitosan blends were assessed by differential scanning calorimetry and dynamic mechanical analysis, respectively. The antibacterial efficacy was measured by a swatch test with bacterial suspensions. The PAN-chitosan nanofibers produced a 5-log reduction against Escherichia coli, Staphylococcus aureus, and Micrococcus luteus.
authors: Department of Textile Engineering & Technology, Yeungnam University, Gyeongsan 712-749, South Korea.
authors: Sam Soo
authors: SS
authors: Kim
authors: Korean Intellectual Property Office, Daejeon 302-701, South Korea. Electronic address: leejaew@hotmail.com.
authors: Jaewoong
authors: J
authors: Lee
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry* / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002152:Calorimetry, Differential Scanning; D048271:Chitosan / Q000737:chemistry* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D016982:Micrococcus luteus / Q000187:drug effects; D008855:Microscopy, Electron, Scanning; D057139:Nanofibers; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000180:Acrylic Resins; D000900:Anti-Bacterial Agents; C010504:polyacrylonitrile; D048271:Chitosan
keywords: Antibacterial; Chitosan; Nanofiber; Polyacrylonitrile