title: The effect of 0.02% mitomycin C injection into the hair follicle with radiofrequency ablation in trichiasis patients.
abstract: OBJECTIVE
  To investigate the inhibitory effect of 0.02% mitomycin C on eyelash regrowth when injected to the eyelash hair follicle immediately after radiofrequency ablation.
  
  
  METHODS
  We prospectively included 21 trichiasis patients from June 2011 to October 2012. Twenty eyes of 14 patients were treated with 0.02% mitomycin C to the hair follicle immediately after radiofrequency ablation in group 1, while radiofrequency ablation only was conducted in ten eyes of seven patients in group 2. Recurrences and complications were evaluated until six months after treatment.
  
  
  RESULTS
  One hundred sixteen eyelashes of 20 eyes in group 1 underwent treatment, and 19 (16.4%) eyelashes recurred. Eighty-four eyelashes of ten eyes in group 2 underwent treatment, and 51 (60.7%) eyelashes recurred. No patients developed any complications related to mitomycin C.
  
  
  CONCLUSIONS
  Application of 0.02% mitomycin C in conjunction with radiofrequency ablation may help to improve the success rate of radiofrequency ablation treatment in trichiasis patients.
authors: Department of Ophthalmology, Gyeongsang National University School of Medicine, Jinju, Korea.
authors: Gyu-Nam
authors: GN
authors: Kim
authors: Department of Ophthalmology, Gyeongsang National University School of Medicine, Jinju, Korea.
authors: Woong-Sun
authors: WS
authors: Yoo
authors: Department of Ophthalmology, Gyeongsang National University School of Medicine, Jinju, Korea. ; Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea.
authors: Seong-Jae
authors: SJ
authors: Kim
authors: Department of Ophthalmology, Gyeongsang National University School of Medicine, Jinju, Korea. ; Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea.
authors: Yong-Seop
authors: YS
authors: Han
authors: Department of Ophthalmology, Gyeongsang National University School of Medicine, Jinju, Korea. ; Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea.
authors: In-Young
authors: IY
authors: Chung
authors: Department of Ophthalmology, Gyeongsang National University School of Medicine, Jinju, Korea. ; Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea.
authors: Jong-Moon
authors: JM
authors: Park
authors: Department of Ophthalmology, Gyeongsang National University School of Medicine, Jinju, Korea. ; Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea.
authors: Ji-Myong
authors: JM
authors: Yoo
authors: Department of Ophthalmology, Gyeongsang National University School of Medicine, Jinju, Korea. ; Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea.
authors: Seong-Wook
authors: SW
authors: Seo
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D017115:Catheter Ablation / Q000379:methods*; D004305:Dose-Response Relationship, Drug; D005140:Eyelashes; D005260:Female; D005500:Follow-Up Studies; D018859:Hair Follicle; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D011446:Prospective Studies; D016896:Treatment Outcome; D058457:Trichiasis / Q000175:diagnosis / Q000628:therapy*
chemical_list: D000903:Antibiotics, Antineoplastic; D016685:Mitomycin
keywords: Ablation techniques; Mitomycin; Trichiasis