title: Two-dimensional accelerated MP-RAGE imaging with flexible linear reordering.
abstract: OBJECTIVE
  Implementation of an accelerated Magnetization Prepared RApid Gradient Echo (MP-RAGE) sequence for T1 weighted neuroimaging; exploiting modern MRI technologies to minimize scan time while preserving the image quality.
  
  
  METHODS
  A custom MP-RAGE sequence was implemented on a state-of-the-art 3T MR scanner equipped with a 32-channel receiver array head coil. The sequence utilized a shifted CAIPIRINHA k y -k z under-sampling pattern combined with elliptical scanning and a two-dimensional view ordering scheme to achieve high parallel imaging acceleration factors at maintained image contrast.
  
  
  RESULTS
  It could be shown that MP-RAGE accelerated in two k-space directions outperforms single direction acceleration, which is the common practice with standard view ordering. Applying the CAIPIRINHA technique in conjunction with elliptical scanning further increased this benefit.
  
  
  CONCLUSIONS
  By combining MP-RAGE with CAIPIRINHA sampling and elliptical scanning, the scan time can be reduced from 4-5 min to 2-3 min with insignificant reduction in image quality.
authors: German Center for Neurodegenerative Diseases (DZNE), Ernst-Robert-Curtius-Straße 12, 53117, Bonn, Germany, daniel.brenner@dzne.de.
authors: Daniel
authors: D
authors: Brenner
authors: Rüdiger
authors: R
authors: Stirnberg
authors: Eberhard D
authors: ED
authors: Pracht
authors: Tony
authors: T
authors: Stöcker
mesh_terms: D016477:Artifacts; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D059906:Neuroimaging / Q000379:methods*; D059629:Signal-To-Noise Ratio; D013997:Time Factors