title: Natural compounds as anticancer agents: Experimental evidence.
abstract: Cancer prevention research has drawn much attention worldwide. It is believed that some types of cancer can be prevented by following a healthy life style. Cancer chemoprevention by either natural or synthetic agents is a promising route towards lowering cancer incidence. In recent years, the concept of cancer chemoprevention has evolved greatly. Experimental studies in animal models demonstrate that the reversal or suppression of premalignant lesions by chemopreventive agents is achievable. Natural occurring agents such as dietary phytochemicals, tea polyphenols and resveratrol show chemopreventive activity in animal models. Moreover, clinical trials for testing the safety and efficacy of a variety of natural agents in preventing or treating human malignancy have been ongoing. Here, we summarize experimental data on the chemopreventive or tumor suppressive effects of several natural compounds including curcumin, (-)-epigallocatechin-3-gallate, resveratrol, indole-3-carbinol, and vitamin D.
authors: Jiao Wang, School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, China.
authors: Jiao
authors: J
authors: Wang
authors: Jiao Wang, School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, China.
authors: Yang-Fu
authors: YF
authors: Jiang
keywords: (-)-Epigallocatechin-3-gallate; Cancer; Chemoprevention; Curcumin; Indole-3-carbinol; Natural agents; Resveratrol; Vitamin D