title: Surgical experience for prolapse of both atrioventricular valves in a patient with filamin A mutation.
abstract: A 21-year-old man underwent mitral valve replacement and tricuspid annuloplasty for severe mitral regurgitation and moderate tricuspid regurgitation. Until the operation, he had been treated for hypermobility type Ehlers-Danlos syndrome. Gene examination revealed a mutation in filamin A gene, which is the gene responsible for X-linked myxomatous valvular dystrophy.
authors: 1Department of Pediatric Cardiovascular Surgery,National Cerebral and Cardiovascular Center,Suita,Osaka,Japan.
authors: Takaya
authors: T
authors: Hoashi
authors: 2Department of Pediatric Cardiology,National Cerebral and Cardiovascular Center,Suita,Osaka,Japan.
authors: Isao
authors: I
authors: Shiraishi
authors: 1Department of Pediatric Cardiovascular Surgery,National Cerebral and Cardiovascular Center,Suita,Osaka,Japan.
authors: Hajime
authors: H
authors: Ichikawa
mesh_terms: D058385:Cardiac Valve Annuloplasty / Q000379:methods*; D064448:Filamins / Q000235:genetics*; D040181:Genetic Diseases, X-Linked / Q000235:genetics*; D006330:Heart Defects, Congenital / Q000235:genetics*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000235:genetics / Q000601:surgery*; D008945:Mitral Valve Prolapse / Q000235:genetics*; D009232:Myxoma / Q000235:genetics*; D014262:Tricuspid Valve Insufficiency / Q000235:genetics / Q000601:surgery*; D055815:Young Adult
chemical_list: D064448:Filamins
keywords: paediatric