title: Venous thromboembolism in women undergoing pelvic reconstructive surgery with mechanical prophylaxis alone.
abstract: OBJECTIVE
  The objective of this study was determine the frequency of symptomatic perioperative venous thromboembolism (VTE) and risk factor(s) associated with VTE occurrence in women undergoing elective pelvic reconstructive surgery using only intermittent pneumatic compression (IPC) for VTE prophylaxis.
  
  
  METHODS
  A multi-center case-cohort retrospective review was conducted at six clinical sites over a 66-month period. All sites utilize IPC as standard VTE prophylaxis for urogynecological surgery. VTE cases occurring during the same hospitalization and up to 6 weeks postoperatively were identified by ICD9 code query. Four controls were temporally matched to each case. Information collected included demographics, medical history, route of surgery, operative time, and intraoperative characteristics. Univariate and multivariate backward stepwise logistic regression analyses were performed to identify potential risk factors for VTE.
  
  
  RESULTS
  Symptomatic perioperative VTE was diagnosed in 27 subjects from a cohort of 10,627 women who underwent elective urogynecological surgery (0.25 %). Univariate analysis identified surgical route (laparotomy vs others), type of surgery ("major" vs "minor"), history of gynecological cancer, surgery time, and patient age as risk factors for VTE (P < 0.05). Multivariate analysis identified increased frequency of VTE with laparotomy, age ≥ 70, and surgery duration ≥ 5 h.
  
  
  CONCLUSIONS
  In our study cohort, the frequency of symptomatic perioperative VTE was low. Laparotomy, age ≥ 70 years, and surgery duration ≥ 5 h were associated with VTE occurrence.
authors: Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center at El Paso, 4800 Alberta Avenue, El Paso, TX, 79905, USA, teodoro.montoya@ttuhsc.edu.
authors: T Ignacio
authors: TI
authors: Montoya
authors: Edgar L
authors: EL
authors: Leclaire
authors: Susan H
authors: SH
authors: Oakley
authors: Andrea K
authors: AK
authors: Crane
authors: Alexandra
authors: A
authors: Mcpencow
authors: Sara
authors: S
authors: Cichowski
authors: David D
authors: DD
authors: Rahn
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D048228:Intermittent Pneumatic Compression Devices; D008875:Middle Aged; D061646:Operative Time; D010388:Pelvis / Q000601:surgery; D059035:Perioperative Period; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D012189:Retrospective Studies; D012307:Risk Factors; D054556:Venous Thromboembolism / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control