title: Catalytic enantioselective intramolecular cyclization of N-aryl diazoamides using a titanium-BINOLate complex.
abstract: Described herein is the use of chiral titanium(IV)-BINOLate to formally implement catalytic asymmetric C(sp(2))-H insertion using N-aryl α-diazoamides. The reaction most likely proceeds via initial asymmetric protonation at the α-carbon of the substrate, followed by the intramolecular electrophilic aromatic substitution.
authors: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto, 606-8502, Japan. maruoka@kuchem.kyoto-u.ac.jp.
authors: Takuya
authors: T
authors: Hashimoto
authors: Kumiko
authors: K
authors: Yamamoto
authors: Keiji
authors: K
authors: Maruoka