title: The relationship of fat soluble antioxidants with gestational diabetes in Iran: a case-control study.
abstract: OBJECTIVE
  The primary aim of this study was to evaluate the relationship of fat soluble antioxidants (retinol and α-tocopherol) with gestational diabetes (GDM).
  
  
  METHODS
  This was a case-control study in which 41 pregnant women with GDM and 41 healthy women were recruited. The inclusion criteria were gestational age ≥32 weeks, singleton foetus, nulliparous or parous women up to four pregnancies and normal fasting blood sugar in the early pregnancy. Two groups were matched regarding age, gestational age and body mass index. A 5 ml venous blood sample were drawn and analysed with the chromatograph for measuring retinol and α-tocopherol. Data were analysed through Chi-square and t test.
  
  
  RESULTS
  The mean serum retinol of the GDM group was 0.46 µg/dl and in the control group it was 0.59 mg/dl (p = 0.01).The mean α-tocopherol in the women with GDM was 6.21 mg/dl and in the control group it was 6.92 mg/dl (p > 0.05).
  
  
  CONCLUSIONS
  The level of retinol in the diabetic pregnant women was significantly lower than that in the control group. This reduction may be due to the reduced antioxidant defences in women with GDM.
authors: Midwifery Department, Reproductive Health Improvement Research Centre, Jundishapur University of Medical Sciences , Ahvaz , Iran and.
authors: Khadijeh
authors: K
authors: Hekmat
authors: Roghieh
authors: R
authors: Bagheri
authors: Parvin
authors: P
authors: Abedi
authors: Hamed
authors: H
authors: Tabesh
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000378:metabolism; D016022:Case-Control Studies; D016640:Diabetes, Gestational / Q000097:blood*; D005260:Female; D006801:Humans; D007492:Iran; D011247:Pregnancy; D014801:Vitamin A / Q000097:blood*; D014810:Vitamin E / Q000097:blood*; D055815:Young Adult
chemical_list: D000975:Antioxidants; D014801:Vitamin A; D014810:Vitamin E
keywords: Iran; antioxidants; gestational diabetes; retinol; α-Tocopherol