title: Water-soluble triscyclometalated organoiridium complex: phosphorescent nanoparticle formation, nonlinear optics, and application for cell imaging.
abstract: Two water-soluble triscyclometalated organoiridium complexes, 1 and 2, with polar side chains that form nanoparticles emitting bright-red phosphorescence in water were synthesized. The optimal emitting properties are related to both the triscyclometalated structure and nanoparticle-forming ability in aqueous solution. Nonlinear optical properties are also observed with the nanoparticles. Because of their proper cellular uptake in addition to high emission brightness and effective two-photon absorbing ability, cell imaging can be achieved with nanoparticles of 2 bearing quaternary ammonium side chains at ultra-low effective concentrations using NIR incident light via the multiphoton excitation phosphorescence process.
authors: Beijing National Laboratory for Molecular Sciences, Department of Applied Chemistry and the Key Laboratory of Polymer Chemistry and Physics of the Ministry of Education, College of Chemistry, Peking University , Beijing 100871, China.
authors: Yuanpeng
authors: Y
authors: Fan
authors: Jingyi
authors: J
authors: Zhao
authors: Qifan
authors: Q
authors: Yan
authors: Peng R
authors: PR
authors: Chen
authors: Dahui
authors: D
authors: Zhao
mesh_terms: D002477:Cells / Q000737:chemistry* / Q000166:cytology; D003584:Cytological Techniques / Q000295:instrumentation*; D005453:Fluorescence; D006367:HeLa Cells; D006801:Humans; D007495:Iridium / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D007495:Iridium