title: Response to "can CYP3A activity be evaluated for drug interaction using a nanogram dose of probe drug?": evaluation of CYP3A activity with microdoses of midazolam.
authors: Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany.
authors: N
authors: N
authors: Hohmann
authors: Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany.
authors: B
authors: B
authors: Halama
authors: Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany.
authors: N
authors: N
authors: Siller
authors: Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany.
authors: G
authors: G
authors: Mikus
authors: Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany.
authors: W E
authors: WE
authors: Haefeli
mesh_terms: D051544:Cytochrome P-450 CYP3A / Q000235:genetics* / Q000378:metabolism*; D005260:Female; D006801:Humans; D007654:Ketoconazole / Q000494:pharmacology*; D008297:Male; D008874:Midazolam / Q000008:administration & dosage* / Q000494:pharmacology*
chemical_list: D051544:Cytochrome P-450 CYP3A; D008874:Midazolam; D007654:Ketoconazole