title: The emerging role of Nrf2 in dermatotoxicology.
abstract: The nuclear factor erythroid 2-related factor 2 (Nrf2) is best known for its role in resistance to oxidant stress. In this issue of EMBO Molecular Medicine, Nrf2-prolonged genetic activation is shown with devastating effects on skin homeostasis. The study provides novel molecular insights into poison-induced chloracne and metabolizing acquired dioxin-induced skin hamartomas or MADISH.
authors: School of Biological Sciences Nanyang Technological University, Singapore City, Singapore.
authors: Nguan S
authors: NS
authors: Tan
authors: Walter
authors: W
authors: Wahli
mesh_terms: D000818:Animals; D054506:Chloracne / Q000378:metabolism*; D006801:Humans; D015603:Keratinocytes / Q000378:metabolism*; D051267:NF-E2-Related Factor 2 / Q000378:metabolism*
chemical_list: D051267:NF-E2-Related Factor 2