title: [The clinical features of 16 cases of primary adenocarcinoma of the third portion of duodenum].
abstract: OBJECTIVE
  To summarize the clinical features of the third portion of duodenum (PATD) for improving the understanding of PATD.
  
  
  METHODS
  Sixteen cases with PATD in Peking Union Medical College Hospital(PUMCH) were retrospectively analyzed.
  
  
  RESULTS
  The most common symptoms of PATD were upper abdominal pain (12/16) , vomiting (9/16) and distention (7/16).On average, the disease had progressed 5.5 months (including 2.5 months of diagnostic workup) before the diagnosis was established. Patients with pathologically poorly differentiated PATD had shorter course of disease (6.5 vs 16.6 months, P = 0.56) and lower chance of cancer-directed surgery (1/8 vs 6/8, P = 0.04) than those with well differentiated PATD. The diagnostic rate was 11/14 by CT scan while only 2/7 by upper gastrointestinal radiography. Three cases were misdiagnosed as superior mesenteric artery syndrome by barium examination.
  
  
  CONCLUSIONS
  PATD should be considered in patients presenting upper abdominal symptoms with negative gastro endoscopy and barium examination.Overall, CT scan plays a pivotal role in diagnosing PATD. Making a correct diagnosis timely can improve the outcome of PATD patients, particularly, in those with poorly differentiated pathology.
authors: Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors: Yun-lu
authors: YL
authors: Feng
authors: Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. Email: dongwu@pumc.edu.cn.
authors: Dong
authors: D
authors: Wu
authors: Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors: Gui-jun
authors: GJ
authors: Fei
authors: Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors: Hui-jun
authors: HJ
authors: Shu
authors: Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors: Jing-nan
authors: JN
authors: Li
authors: Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors: Jia-ming
authors: JM
authors: Qian
mesh_terms: D000328:Adult; D000368:Aged; D004379:Duodenal Neoplasms / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies