title: Variability of resistive indices in the anterior cerebral artery during fontanel compression in preterm and term neonates measured by transcranial duplex sonography.
abstract: OBJECTIVE
  To determine the normal range of resistive index (RI) variability in clinically/neurologically unremarkable preterm and term infants and to compare the hemodynamic response to transient elevation of intracranial pressure.
  
  
  METHODS
  We measured RIs at baseline and following brief fontanel compression, assessing for differences in mean baseline and compression values and percent change.
  
  
  RESULTS
  One hundred and twenty-nine subjects were included in the study. Mean baseline RI and normal range were 0.7 in preterm (0.54 to 0.86) and 0.66 in term infants (0.52 to 0.8; P=0.001). Mean RI during compression was 0.71 in preterm and 0.68 in term infants (P=0.015). Mean percent change between baseline and compression was 5.86% in preterm and 7.45% in term infants (P=0.092).
  
  
  CONCLUSIONS
  No difference in the hemodynamic response to transient elevation of intracranial pressure between different gestational groups, suggesting no significant differences in autoregulatory response.
authors: Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Charlotte R. Bloomberg Children's Center, Sheikh Zayed Tower, Baltimore, MD, USA.
authors: C
authors: C
authors: Zamora
authors: Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Charlotte R. Bloomberg Children's Center, Sheikh Zayed Tower, Baltimore, MD, USA.
authors: A
authors: A
authors: Tekes
authors: Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Charlotte R. Bloomberg Children's Center, Sheikh Zayed Tower, Baltimore, MD, USA.
authors: E
authors: E
authors: Alqahtani
authors: Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Charlotte R. Bloomberg Children's Center, Sheikh Zayed Tower, Baltimore, MD, USA.
authors: O T
authors: OT
authors: Kalayci
authors: 1] Division of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA [2] Neurological Intensive Care Nursery, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors: F
authors: F
authors: Northington
authors: 1] Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Charlotte R. Bloomberg Children's Center, Sheikh Zayed Tower, Baltimore, MD, USA [2] Neurological Intensive Care Nursery, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors: T A G M
authors: TA
authors: Huisman
mesh_terms: D020771:Anterior Cerebral Artery / Q000502:physiology*; D055762:Cranial Fontanelles / Q000000981:diagnostic imaging* / Q000473:pathology; D005865:Gestational Age; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology*; D007234:Infant, Premature / Q000502:physiology*; D012189:Retrospective Studies; D047929:Term Birth; D017585:Ultrasonography, Doppler, Transcranial; D014655:Vascular Resistance / Q000502:physiology*