title: Evolution of the nucleus.
abstract: The nucleus represents a major evolutionary transition. As a consequence of separating translation from transcription many new functions arose, which likely contributed to the remarkable success of eukaryotic cells. Here we will consider what has recently emerged on the evolutionary histories of several key aspects of nuclear biology; the nuclear pore complex, the lamina, centrosomes and evidence for prokaryotic origins of relevant players.
authors: Centro Andaluz de Biología del Desarrollo CABD, Universidad Pablo de Olavide, Sevilla, Spain.
authors: Damien P
authors: DP
authors: Devos
authors: Universität Potsdam, Karl-Liebknecht-Str. 24-25, 14476 Potsdam-Golm, Germany.
authors: Ralph
authors: R
authors: Gräf
authors: Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom. Electronic address: m.c.field@dundee.ac.uk.
authors: Mark C
authors: MC
authors: Field
mesh_terms: D000818:Animals; D005075:Biological Evolution; D001692:Biological Transport; D002467:Cell Nucleus / Q000235:genetics; D006801:Humans; D007797:Laminin / Q000378:metabolism; D008941:Spindle Apparatus / Q000235:genetics
chemical_list: D007797:Laminin