title: Successful treatment of Brugia pahangi in naturally infected cats with ivermectin.
abstract: Lymphatic filariasis is a common parasitic disease of cats in tropical regions including Thailand. The objective of this study was to determine the efficacy of ivermectin against microfilariae of Brugia pahangi in naturally infected cats. Eight cats naturally infected with B. pahangi were divided into control (untreated) and treated groups. Cats in the latter group were given ivermectin injection at 400 µg/kg weekly for 2 months. Microfilariae were counted every week until 48 weeks. Microfilaremia was significantly decreased in the treated group 4 weeks after starting the treatment and become zero at week 9 and afterwards. On the other hand, cats in the control group had high microfilaremia throughout the study. It was successful to treat and control B. pahangi infection in naturally infected cats using ivermectin.
authors: Parasitology Unit, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
authors: Piyanan
authors: P
authors: Taweethavonsawat
authors: Parasitology Unit, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
authors: Sudchit
authors: S
authors: Chungpivat
mesh_terms: D000818:Animals; D017179:Brugia pahangi / Q000302:isolation & purification*; D002371:Cat Diseases / Q000188:drug therapy* / Q000469:parasitology*; D002415:Cats; D004605:Elephantiasis, Filarial / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D005369:Filaricides / Q000008:administration & dosage*; D007559:Ivermectin / Q000008:administration & dosage*; D059208:Parasite Load; D013785:Thailand; D016896:Treatment Outcome
chemical_list: D005369:Filaricides; D007559:Ivermectin
keywords: Brugia pahangi; cat; treatment