title: Potency of insect-specific scorpion toxins on mosquito control using Bacillus thuringiensis Cry4Aa.
abstract: Two insect-specific scorpion toxins, BjαIT and AahIT were produced as alkali-soluble protein inclusions in Escherichia coli. The inclusion bodies themselves exhibited no toxicity against Culex pipiens larvae. However, coadministration with Cry4Aa toxin enhanced the mosquitocidal activity by 2-3 fold. Insect-specific scorpion toxins can be good supplements for Cry toxin-based bioinsecticides.
authors: Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors: Riku
authors: R
authors: Matsumoto
authors: Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors: Yoshitaka
authors: Y
authors: Shimizu
authors: Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan; Department of Entomology, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
authors: Mohammad Tofazzal Hossain
authors: MT
authors: Howlader
authors: Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors: Maho
authors: M
authors: Namba
authors: Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors: Aya
authors: A
authors: Iwamoto
authors: Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors: Hiroshi
authors: H
authors: Sakai
authors: Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan. Electronic address: hayaka-t@cc.okayama-u.ac.jp.
authors: Tohru
authors: T
authors: Hayakawa
mesh_terms: D000818:Animals; D001413:Bacillus thuringiensis / Q000502:physiology*; D003465:Culex / Q000187:drug effects* / Q000382:microbiology / Q000502:physiology; D004926:Escherichia coli; D002479:Inclusion Bodies / Q000378:metabolism; D007306:Insecticides / Q000494:pharmacology; D007814:Larva / Q000187:drug effects / Q000382:microbiology / Q000502:physiology; D007928:Lethal Dose 50; D009032:Mosquito Control; D012604:Scorpion Venoms / Q000096:biosynthesis / Q000235:genetics / Q000494:pharmacology*
chemical_list: D007306:Insecticides; D012604:Scorpion Venoms
keywords: AahIT; Bacillus thuringiensis; BjαIT; Cry4Aa; Culex pipiens; Mosquito control; Scorpion toxins