title: Clinical implications and treatment of dengue.
abstract: Dengue is a common pathogenic disease often proving fatal, more commonly affecting the tropics. Aedes mosquito is the vector for this disease, and outbreaks of dengue often cause mass damage to life. The current review is an effort to present an insight into the causes, etiology, symptoms, transmission, diagnosis, major organs affected, mitigation and line of treatment of this disease with special emphasis on drugs of natural origin. The disease has a potential to spread as an endemic, often claiming several lives and thus requires concerted efforts to work out better treatment options. Traditional medicine offers an alternative solution and could be explored as a safer treatment option. Development of a successful vaccine and immunization technique largely remains a challenge and a better antiviral approach needs to be worked out to complement the supportive therapy. No single synthetic molecule has found to be wholly effective enough to offer curative control and the line of treatment mostly utilizes a combination of fluid replacement and antipyretics-analgesics like molecules to provide symptomatic relief.
authors: Faculty of Pharmacy-Pharmaceutical Chemistry, BBDNITM, Sector-1, Dr. Akhilesh Das Nagar, Faizabad Road, Chinhut Lucknow Lucknow Uttar Pradesh 226028, India. Electronic address: pvchawla@gmail.com.
authors: Pooja
authors: P
authors: Chawla
authors: Faculty of Pharmacy-Pharmaceutical Chemistry, BBDNITM, Sector-1, Dr. Akhilesh Das Nagar, Faizabad Road, Chinhut Lucknow Lucknow Uttar Pradesh 226028, India.
authors: Amrita
authors: A
authors: Yadav
authors: Faculty of Pharmacy-Pharmaceutical Chemistry, BBDNITM, Sector-1, Dr. Akhilesh Das Nagar, Faizabad Road, Chinhut Lucknow Lucknow Uttar Pradesh 226028, India.
authors: Viney
authors: V
authors: Chawla
mesh_terms: D000818:Animals; D003715:Dengue / Q000175:diagnosis / Q000628:therapy*; D053059:Dengue Vaccines / Q000008:administration & dosage; D003716:Dengue Virus / Q000302:isolation & purification; D006801:Humans; D010936:Plant Extracts / Q000008:administration & dosage
chemical_list: D053059:Dengue Vaccines; D010936:Plant Extracts
keywords: Aedes; DHF; DSS; Dengue; Flavivirus