title: Cu(II)-mediated C-H amidation and amination of arenes: exceptional compatibility with heterocycles.
abstract: A Cu(OAc)2-mediated C-H amidation and amination of arenes and heteroarenes has been developed using a readily removable directing group. A wide range of sulfonamides, amides, and anilines function as amine donors in this reaction. Heterocycles present in both reactants are tolerated, making this a broadly applicable method for the synthesis of a family of inhibitors including 2-benzamidobenzoic acids and N-phenylaminobenzoates.
authors: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors: Ming
authors: M
authors: Shang
authors: Shang-Zheng
authors: SZ
authors: Sun
authors: Hui-Xiong
authors: HX
authors: Dai
authors: Jin-Quan
authors: JQ
authors: Yu