title: Characterization of cannabinoid receptors.
abstract: This unit describes the use of cannabinoid radioligands in competitive binding assays for determining affinity parameters (IC50, Ki ) of unlabeled compounds at transfected CB1 and CB2 receptors expressed in cell lines.
authors: GlaxoSmithKline, Research Triangle Park, North Carolina.
authors: Richard F
authors: RF
authors: Cox
authors: GlaxoSmithKline, Research Triangle Park, North Carolina.
authors: Vincent
authors: V
authors: Rash
mesh_terms: D001667:Binding, Competitive / Q000187:drug effects; D001921:Brain / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D006801:Humans; D007202:Indicators and Reagents / Q000494:pharmacology; D011869:Radioligand Assay / Q000379:methods; D043882:Receptors, Cannabinoid / Q000378:metabolism*
chemical_list: D007202:Indicators and Reagents; D043882:Receptors, Cannabinoid
keywords: GPR 55; cannabinoids; receptor binding