title: [Incidence of childhood type I diabetes in Extremadura, Spain, 2003-2007].
abstract: OBJECTIVE
  Studies have shown an increasing incidence of type I diabetes in children in Europe over the last 20 years. The present study was conducted to evaluate the incidence and development of type I diabetes in children under 15 years of age in Extremadura in the period 2003-2007.
  
  
  METHODS
  The study applied the capture-recapture method using the national hospital discharge database as primary source. Data were collected from children under 15 years of age diagnosed with diabetes type I during the study period. Secondary data source were insulin prescriptions from the public health system. Rates were standardised and a Poisson regression was used to assess the development of the disease during the study period.
  
  
  RESULTS
  The overall adjusted incidence rate was 25.2/100.000 (95%CI: 21.8-28.6) with 100% completeness; no significant differences were observed by sex or provinces. Age group rates were 20.2/100.000 (95%CI: 10.1-30.3) for aged 0-4 years, 24.8/100.000 (95%CI: 20.1-29.4) for aged 5-9 years, and 30.0/100.000 (95%CI: 25.8-34.1) for aged 10-14 years, with a RR of 1.67 (95%CI: 1.18-2.36; P=.004) for 10-14 year olds relative to 0-4 year olds. The number of cases among children aged 0-4 years increased from 5 cases in 2003 to 15 cases in 2006, although this increase was not significantly different.
  
  
  CONCLUSIONS
  The overall rates of incidence of type I diabetes were higher than the expected incidence values in Extremadura. Careful surveillance is required to confirm the increased trend in the incidence of type I diabetes observed among children aged 0-4 years.
authors: Servicio de Endocrinología, Hospital Regional Universitario Infanta Cristina, Badajoz, España; Facultad de Medicina, Universidad de Extremadura, Badajoz, España.
authors: A
authors: A
authors: Gimeno Benítez
authors: Servicio de Endocrinología, Hospital Regional Universitario Infanta Cristina, Badajoz, España; Facultad de Medicina, Universidad de Extremadura, Badajoz, España.
authors: L M
authors: LM
authors: Luengo Pérez
authors: Servicio de Endocrinología, Hospital Regional Universitario Infanta Cristina, Badajoz, España; Facultad de Medicina, Universidad de Extremadura, Badajoz, España.
authors: P
authors: P
authors: Suero Villa
authors: Facultad de Medicina, Universidad de Extremadura, Badajoz, España.
authors: S
authors: S
authors: Suero Villa
authors: Medicina de Familia, Centro de Salud de Talavera la Real, Talavera la Real, Badajoz, España; Cátedra de Medicina de Familia SEMERGEN, Facultad de Medicina, Universidad de Extremadura, Badajoz, España. Electronic address: jsvega@unex.es.
authors: J
authors: J
authors: Sánchez Vega
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007328:Insulin / Q000008:administration & dosage*; D008297:Male; D016012:Poisson Distribution; D013030:Spain / Q000453:epidemiology
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin
keywords: Children; Diabetes tipo 1; Incidence; Incidencia; Infantil; Tendencia; Trend; Type I diabetes