title: Changes in condom use during the first year of HIV treatment in Uganda and the relationship to depression.
abstract: OBJECTIVE
  We examined the effect of antiretroviral therapy (ART), and the predictive role of depression, on condom use with primary partners.
  
  
  METHODS
  Data from three studies in Uganda were combined into a sample of 750 patients with a primary sex partner, with 502 starting ART and 248 entering HIV care, and followed for 12 months. Random-effects logistic regression models were used to examine the impact of ART, and the influence of baseline level and change in depression, on condom use with primary partners.
  
  
  RESULTS
  At month 12, 61 % ART and 67 % non-ART patients were consistent condom users, compared to 44 and 41 % at baseline, respectively. Multivariate analysis revealed that consistent condom use increased similarly for ART and non-ART patients, and that minor depression at baseline and increased depression over time predicted inconsistent condom use.
  
  
  CONCLUSIONS
  Improved depression diagnosis and treatment could benefit HIV prevention.
authors: RAND Corporation, 1776 Main St., Santa Monica, CA, 90407, USA, gwagner@rand.org.
authors: Glenn J
authors: GJ
authors: Wagner
authors: Bonnie
authors: B
authors: Ghosh-Dastidar
authors: Mary Ellen
authors: ME
authors: Slaughter
authors: Dickens
authors: D
authors: Akena
authors: Noeline
authors: N
authors: Nakasujja
authors: Seggane
authors: S
authors: Musisi
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D017280:Condoms / Q000706:statistics & numerical data*; D003863:Depression / Q000150:complications / Q000523:psychology*; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy / Q000523:psychology*; D006801:Humans; D008297:Male; D011795:Surveys and Questionnaires; D014454:Uganda / Q000453:epidemiology
chemical_list: D019380:Anti-HIV Agents