title: Evaluation of endometrial cytology prepared with the Becton Dickinson SurePath™ method: a pilot study by the Osaki Study Group.
abstract: OBJECTIVE
  To evaluate the sensitivity and specificity of the BD SurePath™ liquid-based Papanicolaou test for assessing the cytology of intrauterine endometrial samples according to newly devised cytological diagnostic criteria and a novel descriptive reporting format.
  
  
  METHODS
  One hundred and twenty-two endometrial samples were analyzed. All samples were obtained directly from the intrauterine cavity using the Uterobrush or Honest Super Brush. The samples used for the histological examination and cytological tests were collected simultaneously. Our study group devised new cytological diagnostic criteria for examining endometrial samples: the Osaki Study Group method. In this study, histological diagnosis was considered to be the gold standard for cytological diagnosis. A novel descriptive reporting format was also used.
  
  
  RESULTS
  Satisfactory cytological specimens were obtained in all cases. The sensitivity and specificity of the SurePath endometrial cytological examination method were 96.4 and 100%, respectively.
  
  
  CONCLUSIONS
  These results indicate that the SurePath method is acceptable for clinical use. Since the SurePath method seems to be easier and allows greater preparation standardization than the conventional method, coupling it with our newly devised cytological diagnostic criteria and descriptive reporting format might represent a reliable diagnostic method for assessing endometrial specimens.
authors: Department of Obstetrics and Gynecology, JA Suzuka General Hospital, Suzuka, Japan.
authors: Kenji
authors: K
authors: Yanoh
authors: Yoshiaki
authors: Y
authors: Norimatsu
authors: Satoru
authors: S
authors: Munakata
authors: Toshiya
authors: T
authors: Yamamoto
authors: Yutaka
authors: Y
authors: Nakamura
authors: Tetsuya
authors: T
authors: Murata
authors: Tadao K
authors: TK
authors: Kobayashi
authors: Yasuo
authors: Y
authors: Hirai
mesh_terms: D003581:Cytodiagnosis / Q000379:methods* / Q000592:standards; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D010865:Pilot Projects; D012680:Sensitivity and Specificity; D014626:Vaginal Smears / Q000379:methods* / Q000592:standards