title: A fatal case of seronegative, late-onset systemic lupus erythematosus presenting with motor sensory axonal polyneuropathy.
abstract: Systemic lupus erythematosus is a multisystemic, autoimmune, inflammatory disorder predominantly affecting young females. Its onset may be abrupt or insidious, presenting with a broad range of clinical and immunological features. We report an unusual case of elderly-onset systemic lupus erythematosus in a woman initially diagnosed with discoid lupus, and subsequently admitted to hospital due to a progressive psycho-motor deficit. Electrophysiological measurements suggested a diagnosis of acute motor sensory axonal neuropathy. Unusual clinical features and negative serology led to diagnostic uncertainty. This case report offers information on the course of the disease through the entire chain of the health care delivery (from primary to tertiary). Despite the efforts of the hospital staff, it was not possible to save the life of the woman.
authors: Primary Health Care Centre of Kissamos , Kissamos, Crete , Greece.
authors: Dimitrios
authors: D
authors: Anyfantakis
authors: Emmanouil K
authors: EK
authors: Symvoulakis
authors: Emmanouil
authors: E
authors: Barbounakis
authors: Miltiades
authors: M
authors: Kastanakis
authors: Evangelos
authors: E
authors: Athanasakis
authors: Evangelos
authors: E
authors: Blevrakis
authors: Serafeim
authors: S
authors: Kastanakis
mesh_terms: D000368:Aged; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D011115:Polyneuropathies / Q000209:etiology*
keywords: Discoid lupus; Lupus erythematosus systemic; Lupus pneumonitis; Motor sensory axonal polyneuropathy