title: Dynamic computerised hand dynamometry: measuring outcomes following upper limb botulinum toxin-A injections in adults with acquired brain injury.
abstract: OBJECTIVE
  Evaluate upper limb performance in adults receiving botulinum toxin-A injections for upper limb spasticity using Dynamic Computerised Hand Dynamometry and current clinical measures.
  
  
  METHODS
  Pre-test/post-test clinical intervention study.
  
  
  METHODS
  Twenty-eight participants with spasticity following acquired brain injury.
  
  
  METHODS
  Botulinum toxin-A effects were measured 4 weeks post-injection using Dynamic Computerised Dynamometry. Current clinical upper limb performance measures spanning the International Classification of Functioning, Disability and Health domains were also conducted at the Body Function and Structure (Modified Ashworth Scale; Tardieu Scale) and Activity (Action Research Arm Test; Goal Attainment Scaling; patient disability and carer burden scales) domains. Dynamic Computerised Dynamometry hand performance measures were correlated with performance on current clinical measures.
  
  
  RESULTS
  Significant post botulinum toxin-A changes were identified on current clinical measures and the Dynamic Computerised Dynamometry. Dynamic Computerised Dynamometry results correlated with current clinical measures demonstrating functional upper limb change across the Body Function and Structure and Activity domains.
  
  
  CONCLUSIONS
  Dynamic Computerised Dynamometry sensitively assesses the effects of botulinum toxin-A on upper limb spasticity during a simple, functionally based, grasp and release task. Unlike current measures, the Dynamic Computerised Dynamometry provides information across the Body Function and Structure and Activity domains of the International Classification of Function.
authors: Brain Injury Rehabilitation Service, Westmead Hospital, 2145 Wentworthville, Australia. hbar1204@uni.sydney.edu.au,hannah.barden@swahs.health.nsw.gov.au.
authors: Hannah L
authors: HL
authors: Barden
authors: Ian J
authors: IJ
authors: Baguley
authors: Melissa T
authors: MT
authors: Nott
authors: Chrisine
authors: C
authors: Chapparo
mesh_terms: D001132:Arm / Q000503:physiopathology; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D001930:Brain Injuries / Q000150:complications*; D017281:Cost of Illness; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D005260:Female; D006225:Hand / Q000503:physiopathology; D018737:Hand Strength; D006801:Humans; D008297:Male; D008875:Middle Aged; D009128:Muscle Spasticity / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D053581:Muscle Strength Dynamometer
chemical_list: D019274:Botulinum Toxins, Type A