title: Molecular modeling of nucleic acid structure.
abstract: This unit is the first in a series of four units covering the analysis of nucleic acid structure by molecular modeling. The unit provides an overview of the computer simulation of nucleic acids. Topics include the static structure model, computational graphics and energy models, the generation of an initial model, and characterization of the overall three-dimensional structure.
authors: Department of Medicinal Chemistry, College of Pharmacy, University of Utah, Salt Lake City, Utah.
authors: Rodrigo
authors: R
authors: Galindo-Murillo
authors: Department of Medicinal Chemistry, College of Pharmacy, University of Utah, Salt Lake City, Utah.
authors: Christina
authors: C
authors: Bergonzo
authors: Department of Medicinal Chemistry, College of Pharmacy, University of Utah, Salt Lake City, Utah.
authors: Thomas E
authors: TE
authors: Cheatham
mesh_terms: D003198:Computer Simulation; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009696:Nucleic Acids / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D009696:Nucleic Acids
keywords: experimental determination of structure; folding and conformational change; nucleic acid chemistry; nucleic acid structure and folding; structural analysis of biomolecules