title: Histone glutamine methylation afFACTing rDNA transcription.
abstract: Chemical modifications of histone proteins directly and indirectly affect chromatin structure and thereby contribute to the multilayered control of diverse DNA-based processes. A recent study in Nature enriches this list of enzyme-dependent posttranslational histone marks by H2A glutamine methylation that appears to be dedicated to only one specific cellular process, the regulation of nucleolar rDNA transcription.
authors: Department of Biology II, Humanbiology and Bioimaging, Center for Integrated Protein Science (CIPSM), Ludwig Maximilians University Munich, 82152 Planegg-Martinsried, Germany.
authors: Heinrich
authors: H
authors: Leonhardt
authors: Molecular Biology Unit, Adolf-Butenandt-Institute, Center for Integrated Protein Science Munich (CIPSM), Ludwig Maximilians University Munich, 80336 Munich, Germany.
authors: Sandra B
authors: SB
authors: Hake
mesh_terms: D005973:Glutamine / Q000378:metabolism*; D006657:Histones / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D012318:RNA Polymerase I / Q000378:metabolism*
chemical_list: D006657:Histones; D005973:Glutamine; D012318:RNA Polymerase I