title: Screening of major depression in epilepsy: the Neurologic Depression Disorders Inventory in Epilepsy-Spanish version (Argentina).
abstract: OBJECTIVE
  To validate and translate the English version of the Neurologic Depression Disorders Inventory in Epilepsy (NDDI-E) into Spanish as a screening instrument for major depressive episodes (MDE) for patients with epilepsy from Argentina and Uruguay.
  
  
  METHODS
  One hundred fifty-five consecutive outpatients with epilepsy participated in this study. The module of MDE of the MINI International Neuropsychiatric Instrument (MINI Plus version) was used as the gold standard against which the translated version of the NDDI-E was validated.
  
  
  RESULTS
  Among the 155 patients, 25 (16%) met Diagnostic and Statistical Manual, Fourth Edition (DSM-IV) criteria for MDE according to the MINI. With a total score of >15, The NDDI-E identified MDE with an 80% sensitivity, 90% specificity, 60% positive predictive value, and 95.5% negative predictive value.
  
  
  CONCLUSIONS
  These data indicate that the Spanish version of the NDDI-E can reliably identify MDE in patients with epilepsy from Argentina and Uruguay.
authors: Department of Neurology, Institute of Neurosciences at Favaloro University, Buenos Aires, Argentina; Institute of Cognitive Neurology (INECO), Buenos Aires, Argentina; Department of Neurology, British Hospital, Buenos Aires, Argentina.
authors: Alfredo E
authors: AE
authors: Thomson
authors: Analía
authors: A
authors: Calle
authors: María E
authors: ME
authors: Fontela
authors: Luis
authors: L
authors: Yepez
authors: Francisco
authors: F
authors: Muñoz Giacomelli
authors: Agustín
authors: A
authors: Jáuregui
authors: Juan M
authors: JM
authors: Racosta
authors: Andrés M
authors: AM
authors: Kanner
mesh_terms: D000293:Adolescent; D000328:Adult; D001118:Argentina / Q000453:epidemiology; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D004827:Epilepsy / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods / Q000592:standards*; D008875:Middle Aged; D019303:Multilingualism; D011569:Psychiatric Status Rating Scales / Q000592:standards; D014583:Uruguay / Q000453:epidemiology; D055815:Young Adult
keywords: Antidepressant drugs; Focal epilepsy; Generalized epilepsy; Major depressive disorder; Mini International Neuropsychiatric Inventory; Treatment-resistant epilepsy