title: [Clinicopathologic characteristics of basal cell carcinoma of the prostate: analysis of 5 cases and review of the literature].
abstract: OBJECTIVE
  To investigate the histogenesis, clinicopathologic characteristics, pathologic diagnosis, differential diagnosis, treatment and prognosis of basal cell carcinoma of the Prostate (BCCP).
  
  
  METHODS
  We conducted clinicopathologic analysis on the manifestations of 5 cases of BCCP by HE staining and immunohistochemistry and reviewed relevant literature.
  
  
  RESULTS
  Microscopically, the tumor cells were small in volume with ovoid karyomegaly and mitosis, some arranged like a solid nest or with a cribriform appearance. The tumors displayed an invasive growth, with positive expressions of 34betaE12, P63 and Cytokeratin 14, and negative expressions of PSA and P504s. No recurrence and metastasis were found in these patients during over 12 months of follow-up after surgery.
  
  
  CONCLUSIONS
  BCCP is a rare neoplasm different from prostate adenocarcinoma. Immunohistochemistry is indispensable in distinguishing this tumor from other types of prostatic carcinoma. Its biological behavior remains to be further studied. The best treatment option may be radical surgery combined with chemo-radiotherapy at the present time.
authors: Department of Pathology, The First Peoples Hospital of Neijiang City, Neijiang, Sichuan 641000, China. 52541062@qq.com
authors: Yu
authors: Y
authors: Wang
authors: Department of Pathology, The First Peoples Hospital of Neijiang City, Neijiang, Sichuan 641000, China.
authors: Peng
authors: P
authors: Guo
authors: Department of Pathology, The First Peoples Hospital of Neijiang City, Neijiang, Sichuan 641000, China.
authors: Qing-Song
authors: QS
authors: Liu
authors: Department of Pathology, The First Peoples Hospital of Neijiang City, Neijiang, Sichuan 641000, China.
authors: Xiao-Chuan
authors: XC
authors: Xie
authors: Department of Pathology, The First Peoples Hospital of Neijiang City, Neijiang, Sichuan 641000, China.
authors: Cong-Yang
authors: CY
authors: Gu
authors: Department of Pathology, The First Peoples Hospital of Neijiang City, Neijiang, Sichuan 641000, China.
authors: Min
authors: M
authors: Jing
authors: Department of Pathology, The First Peoples Hospital of Neijiang City, Neijiang, Sichuan 641000, China.
authors: Gui-Ping
authors: GP
authors: Liu
mesh_terms: D000368:Aged; D002280:Basal Cell Carcinoma / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000473:pathology*