title: [Yuleshu oral mixture combined with conventional therapy for chronic prostatitis].
abstract: OBJECTIVE
  To evaluate the clinical effects of Yuleshu oral mixture combined with conventional therapy on chronic prostatitis.
  
  
  METHODS
  Eighty-eight patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) were equally randomized to a control and an experimental group to receive conventional therapy (oral antibiotics, alpha blockers, proprietary Chinese medicine for activating blood circulation and massage of the prostate) and conventional therapy combined with Yuleshu oral mixture respectively. Before and after treatment, the severity of symptoms and sexual function of the patients were evaluated using NIH-CPSI and IIEF-5, their anxiety, depression and other emotional problems assessed with Hamilton Depression Rating Scale (HAMD) and Hamilton Anxiety Scale (HAMA), and the results subjected to statistical analysis.
  
  
  RESULTS
  Both the experimental and control groups showed significant improvement in prostatitis symptoms and sexual function after treatment as compared with the baseline (P < 0.01), even more significant in the former than in the latter group, especially in pain symptoms (7.89 +/- 2.82 vs 10.41 +/- 2.55, P < 0.01). Before and after treatment, the HAMA and HAMD score had no significant difference in the control, but there was significant difference in the experimental group. The experimental group exhibited remarkably higher scores after than before treatment on HAMA (24.30 +/- 5.07 vs 13.80 +/- 3.62, P < 0.01) and HAMD (23.81 +/- 5.01 vs 16.23 +/- 5.93, P < 0.01), but not the control group (P > 0.05).
  
  
  CONCLUSIONS
  Yuleshu oral mixture can effectively relieve anxiety, depression and other psychological problems in CP/CPPS patients, and improve their clinical symptoms as well. Therefore, it is an effective drug for chronic prostatitis.
authors: Department of Urology, The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610072, China.
authors: Yu-Guo
authors: YG
authors: Xia
authors: Department of Urology, The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610072, China.
authors: Wen-Tong
authors: WT
authors: Zeng
authors: Department of Urology, The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610072, China.
authors: Xue-Feng
authors: XF
authors: Mei
authors: Department of Clinical Laboratory, Sichuan Academy of Medical Sciences/Sichuan Provincial People's Hospital, Chengdu, Sichuan 610072, China.
authors: Xin
authors: X
authors: Liu
authors: Department of Urology, The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610072, China.
authors: Guang-Sen
authors: GS
authors: Li
authors: Department of Urology, The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610072, China.
authors: Jian
authors: J
authors: Cai
authors: Department of Clinical Laboratory, The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610072, China.
authors: Bo
authors: B
authors: Wu
authors: Department of Urology, The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610072, China.
authors: Ping
authors: P
authors: Gao
mesh_terms: D000293:Adolescent; D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D000328:Adult; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017699:Pelvic Pain / Q000188:drug therapy; D011472:Prostatitis / Q000188:drug therapy*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000317:Adrenergic alpha-Antagonists; D004365:Drugs, Chinese Herbal