title: [Epidemiological aspects of gastroesophageal reflux disease in children in the conditions of large industrial city].
abstract: BACKGROUND
  Epidemiology of gastroesophageal reflux disease in childhood is insufficiently studied.
  
  
  OBJECTIVE
  To evaluate the frequency of typical GERD symptoms in older children and adolescents in Minsk, and to determine of reflux-esophagitis (RE) on results of endoscopic investigation.
  
  
  METHODS
  1576 children and adolescents 12-18 years old were interviewed. The frequency of heartburn, regurgitation, acid and bitter belching and swallowing disturbances was analyzed. Endoscopic frequency of RE was evaluated in 3830 children in 2010 and in 1361--in 2005.
  
  
  RESULTS
  Typical complaints were found in 19.7% respondents, more often acid belching (8.4%), heartburn (7.4%), regurgitation (7.0%) and combined symptoms (7.2%). According endoscopic data the spreading of RE was 18.7% in 2005 and 18.8% in 2010, but the frequency of erosive esophagitis increased from 12.5% to 30.5%. Erosive esophagitis formed more often in boys and in older children, does not depend from Helicobacter pylori and accompanied gastritis.
  
  
  CONCLUSIONS
  High frequency of typical GERD complaints is determined in childhood. Endoscopy reflects significant growth of erosive esophagitis under constant frequency of RE on the whole.
authors: S È
authors: SÈ
authors: Zagorskiĭ
authors: A V
authors: AV
authors: Korzhik
authors: T Iu
authors: TIu
authors: Fursa
authors: E V
authors: EV
authors: Pechkovskaia
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D005260:Female; D005764:Gastroesophageal Reflux / Q000453:epidemiology*; D006801:Humans; D008297:Male; D002094:Republic of Belarus / Q000453:epidemiology; D012737:Sex Factors; D014505:Urban Population