title: Consensus of the Brazilian Society of Infectious Diseases and Brazilian Society of Clinical Oncology on the management and treatment of Kaposi's sarcoma.
abstract: Kaposi's sarcoma is a multifocal vascular lesion of low-grade potential that is most often present in mucocutaneous sites and usually also affects lymph nodes and visceral organs. The condition may manifest through purplish lesions, flat or raised with an irregular shape, gastrointestinal bleeding due to lesions located in the digestive system, and dyspnea and hemoptysis associated with pulmonary lesions. In the early 1980s, the appearance of several cases of Kaposi's sarcoma in homosexual men was the first alarm about a newly identified epidemic, acquired immunodeficiency syndrome. In 1994, it was finally demonstrated that the presence of a herpes virus associated with Kaposi's sarcoma called HHV-8 or Kaposi's sarcoma herpes virus and its genetic sequence was rapidly deciphered. The prevalence of this virus is very high (about 50%) in some African populations, but stands between 2% and 8% for the entire world population. Kaposi's sarcoma only develops when the immune system is depressed, as in acquired immunodeficiency syndrome, which appears to be associated with a specific variant of the Kaposi's sarcoma herpes virus. There are no treatment guidelines for Kaposi's sarcoma established in Brazil, and thus the Brazilian Society of Clinical Oncology and the Brazilian Society of Infectious Diseases developed the treatment consensus presented here.
authors: Sociedade Brasileira de Infectologia Infectologia, Vila Mariana, SP, Brazil.
authors: Érico
authors: É
authors: Arruda
authors: Hospital Mater Dei, Belo Horizonte, MG, Brazil.
authors: Alexandre Andrade dos Anjos
authors: AA
authors: Jacome
authors: Instituto de Infectologia Emílio Ribas e Centro de Referência e Treinamento em DST/AIDS, São Paulo, SP, Brazil. Electronic address: analuizaconde@ig.com.br.
authors: Ana Luiza de Castro Conde
authors: AL
authors: Toscano
authors: Sociedade Brasileira de Oncologia Clínica e Grupo Acreditar, Brasília, DF, Brazil.
authors: Anderson Arantes
authors: AA
authors: Silvestrini
authors: Hospital Santa Lúcia, Brasília, DF, Brazil.
authors: André Santa Bárbara
authors: AS
authors: Rêgo
authors: Sociedade Brasileira de Oncologia Clínica, Brasília, DF, Brazil.
authors: Evanius Garcia
authors: EG
authors: Wiermann
authors: Hospital da Baleia Belo Horizonte, MG, Brazil.
authors: Geraldo Felicio da
authors: GF
authors: Cunha
authors: Hospital das Clínicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil.
authors: Heloisa Ramos Lacerda de
authors: HR
authors: Melo
authors: Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto, SP, Brazil.
authors: Karen Mirna Loro
authors: KM
authors: Morejón
authors: Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
authors: Luciano Zubaran
authors: LZ
authors: Goldani
authors: Hospital Dia, Instituto de Infectologia Emilio Ribas, São Paulo, SP, Brazil.
authors: Luiz Carlos
authors: LC
authors: Pereira
authors: Centro de Referência e Treinamento-DST-AIDS, São Paulo, SP, Brazil.
authors: Mariliza Henrique
authors: MH
authors: Silva
authors: Serviço de Infectologia de Rede Hospitalar Privada e Câmara Técnica de Doenças Infecciosas do CREMERJ.
authors: Mauro Sergio
authors: MS
authors: Treistman
authors: Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, MG, Brazil.
authors: Mônica Cristina Toledo
authors: MC
authors: Pereira
authors: Hospital São Camilo, São Paulo, SP, Brazil.
authors: Patricia Maria Bezerra Xavier
authors: PM
authors: Romero
authors: Centro de Oncologia Antonio Ermirio de Moraes São Paulo, SP, Brazil.
authors: Rafael Aron
authors: RA
authors: Schmerling
authors: Centro de Oncologia do Hospital Sírio-Libanês, São Paulo, SP, Brazil.
authors: Rodrigo Antonio Vieira
authors: RA
authors: Guedes
authors: Instituto do Câncer do Estado de São Paulo e do Hospital Sírio Libanês, São Paulo, SP, Brazil.
authors: Veridiana Pires de
authors: VP
authors: Camargo
mesh_terms: D001938:Brazil; D005260:Female; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D012307:Risk Factors; D012514:Sarcoma, Kaposi / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D012955:Societies, Medical
keywords: AIDS; Consensus; Cutaneous; Kaposi's sarcoma