title: Diagnostic accuracy of three biopsy techniques in 117 dogs with intra-nasal neoplasia.
abstract: OBJECTIVE
  To determine if nasal biopsies taken at rhinoscopy are more accurate for diagnosing neoplasia than biopsies taken blindly or using advanced imaging for guidance.
  
  
  METHODS
  A retrospective study of 117 dogs with nasal mass lesions that were divided into three groups according to the method of nasal biopsy collection; advanced imaging-guided, rhinoscopy-guided and blind biopsy. Signalment, imaging and rhinoscopic findings, and histopathological diagnosis were compared between groups. The proportion of first attempt biopsies confirming neoplasia were determined for each group.
  
  
  RESULTS
  There were no statistically significant differences in the proportion of biopsies that confirmed neoplasia obtained via advanced imaging-guided, rhinoscopy-guided or blind biopsy techniques.
  
  
  CONCLUSIONS
  In dogs with a high index of suspicion of nasal neoplasia, blind biopsy may be as diagnostic as rhinoscopy-guided biopsy. Repeated biopsies are frequently required for definitive diagnosis.
authors: Northwest Surgeons, Delamere House, Ashville Point, Sutton Weaver, Cheshire, WA7 3FW.
authors: B J
authors: BJ
authors: Harris
authors: B N
authors: BN
authors: Lourenço
authors: J M
authors: JM
authors: Dobson
authors: M E
authors: ME
authors: Herrtage
mesh_terms: D000818:Animals; D001706:Biopsy / Q000379:methods / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D004724:Endoscopy / Q000379:methods / Q000662:veterinary; D009666:Nose / Q000473:pathology; D009669:Nose Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D012189:Retrospective Studies