title: The epidemiology of status epilepticus in the United States.
abstract: OBJECTIVE
  To summarize trends in status epilepticus (SE) in the United States by age, race, sex, admission source, disposition, incidence rates, and mortality.
  
  
  METHODS
  Data from US National Hospital Discharge Survey were used from 1979 to 2010 to identify discharges with SE and common etiologies and complications of SE using International Classification of Diseases, 9th Revision, Clinical Modifications codes. Temporal trends in the incidence and in-hospital mortality of SE were examined with respect to age, sex, and race.
  
  
  RESULTS
  We identified 760,117 discharges with SE over 32 years. The incidence of SE increased from 3.5 to 12.5/100,000 between 1979 and 2010, without a significant change in in-hospital mortality. Higher incidence, earlier age of onset, and higher mortality were observed among males. Age stratification revealed a "U-shaped" distribution with higher incidence at age <10 years (14.3/100,000) and age >50 years (approaching 28.4/100,000). In-hospital mortality, however, was the lowest (2.6 %) at age <10 years and approached 20.2 % with age ≥80 years. The incidence of SE was higher among blacks (13.7/100,000), compared to whites (6.9/100,000) and other races (7.4/100,000). Mortality, however, was lower among blacks (7.2 %) compared to whites and other races (9.8 and 9.2 %, respectively). Black men had the highest incidence (15.0/100,000), relatively younger age of onset (39.3 years) and the lowest mortality (5.6 %). A net temporal decline in the reported prevalence of epilepsy, central nervous system infections, and traumatic brain injury was noted among SE cohort.
  
  
  CONCLUSIONS
  The incidence of SE increased nearly fourfold with relatively unchanged mortality. Gender and racial disparities exist in the incidence of SE, and age is an important predictor of mortality.
authors: Department of Neurology, Cooper University Hospital, 3 Cooper Plaza, Camden, NJ, USA, bhavpreet@hotmail.com.
authors: Bhavpreet S
authors: BS
authors: Dham
authors: Krystal
authors: K
authors: Hunter
authors: Fred
authors: F
authors: Rincon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D044383:Black People / Q000706:statistics & numerical data; D015897:Comorbidity; D005260:Female; D019538:Health Care Surveys / Q000706:statistics & numerical data; D017052:Hospital Mortality / Q000208:ethnology / Q000639:trends; D006801:Humans; D015994:Incidence; D007902:Length of Stay / Q000706:statistics & numerical data / Q000639:trends; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge / Q000706:statistics & numerical data / Q000639:trends; D015995:Prevalence; D012307:Risk Factors; D013226:Status Epilepticus / Q000453:epidemiology* / Q000208:ethnology / Q000401:mortality; D014481:United States / Q000453:epidemiology; D044465:White People / Q000706:statistics & numerical data; D055815:Young Adult; D001741:Black or African American