title: The spatial summation characteristics of three categories of V1 neurons differing in non-classical receptive field modulation properties.
abstract: The spatial summation of excitation and inhibition determines the final output of neurons in the cat V1. To characterize the spatial extent of the excitatory classical receptive field (CRF) and inhibitory non-classical receptive field (nCRF) areas, we examined the spatial summation properties of 169 neurons in cat V1 at high (20-90%) and low (5-15%) stimulus contrasts. Three categories were classified based on the difference in the contrast dependency of the surround suppression. We discovered that the three categories significantly differed in CRF size, peak firing rate, and the proportion of simple/complex cell number. The classification of simple and complex cells was determined at both high and low contrasts. While the majority of V1 neurons had stable modulation ratios in their responses, 10 cells (6.2%) in our sample crossed the classification boundary under different stimulus contrasts. No significant difference was found in the size of the CRF between simple and complex cells. Further comparisons in each category determined that the CRFs for complex cells were significantly larger than those for simple cells in category type I neurons, with no significant differences between simple and complex cells in category type II and type III neurons. In addition, complex cells have higher peak firing rates than simple cells.
authors: Key Laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China. Electronic address: chenke0703@163.com.
authors: Ke
authors: K
authors: Chen
authors: Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
authors: Xue-Mei
authors: XM
authors: Song
authors: Key Laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China.
authors: Zheng-Qiang
authors: ZQ
authors: Dai
authors: Key Laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China.
authors: Jiao-Jiao
authors: JJ
authors: Yin
authors: Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
authors: Xing-Zhen
authors: XZ
authors: Xu
authors: Key Laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China; Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
authors: Chao-Yi
authors: CY
authors: Li
mesh_terms: D000818:Animals; D002415:Cats / Q000502:physiology*; D015350:Contrast Sensitivity / Q000502:physiology; D005074:Evoked Potentials, Visual / Q000502:physiology*; D023421:Models, Animal; D009474:Neurons / Q000502:physiology*; D010775:Photic Stimulation / Q000379:methods; D014793:Visual Cortex / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*
keywords: Complex cells; Difference of Gaussians; Primary visual cortex; Simple cells; Spatial summation; Stimulus contrast