title: [Molecular features of human bocavirus from infantile diarrhea in Suzhou area, Jiangsu province in 2010-2011].
abstract: OBJECTIVE
  To investigate the status of human bocavirus and to identify its epidemiological characteristics as well as genotype distribution in patients with infantile viral diarrhea in Suzhou, Jiangsu province.
  
  
  METHODS
  832 fecal specimens from patients with infantile virus diarrhea cases were collected from Suzhou Children's Hospital in 2010-2011. Human bocavirus were detected by Real-Time RT-PCR, and genotype were determined by sequence analysis.
  
  
  RESULTS
  Among all the fecal specimens, 51 (6.1%) cases were positive for human bocavirus. The peak season of rotavirus infection was between July and September. Of all the episodes on rotavirus diarrhea, 96% occurred before 2 years of age, with peaks in children with 7-12 months of age. Data from Nucleotide Sequence analysis showed that among 28 samples that carrying HBoV-1, 5 strains belonged to HBoV-2, HBoV type 3 but type 4 were absent.
  
  
  CONCLUSIONS
  Human bocavirus were detected from fecal specimens of infantile virus diarrhea in Suzhou, with genotype HBoV-1 as the major strain. HBoV-2 genotype was also found.
authors: Key Laboratory of Enteric Pathogenic Microbiology, Ministry of Health, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors: Jian-guang
authors: JG
authors: Fu
authors: Nanjing Maternity and Child Health Care Hospital.
authors: Cui-lian
authors: CL
authors: Jiang
authors: Key Laboratory of Enteric Pathogenic Microbiology, Ministry of Health, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors: Yuan-fang
authors: YF
authors: Qin
authors: Key Laboratory of Enteric Pathogenic Microbiology, Ministry of Health, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors: Jing
authors: J
authors: Ai
authors: Suzhou Center for Disease Control and Prevention.
authors: Cheng
authors: C
authors: Liu
authors: Key Laboratory of Enteric Pathogenic Microbiology, Ministry of Health, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors: Bin
authors: B
authors: Wu
authors: Key Laboratory of Enteric Pathogenic Microbiology, Ministry of Health, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors: Xian
authors: X
authors: Qi
authors: Key Laboratory of Enteric Pathogenic Microbiology, Ministry of Health, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors: Chang-jun
authors: CJ
authors: Bao
authors: Key Laboratory of Enteric Pathogenic Microbiology, Ministry of Health, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors: Ye-fei
authors: YF
authors: Zhu
authors: Key Laboratory of Enteric Pathogenic Microbiology, Ministry of Health, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China. Email: tfyepi@jscdc.cn.
authors: Fen-yang
authors: FY
authors: Tang
mesh_terms: D002681:China / Q000453:epidemiology; D003968:Diarrhea, Infantile / Q000453:epidemiology* / Q000821:virology*; D005260:Female; D005838:Genotype; D056661:Human bocavirus / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D008297:Male; D010802:Phylogeny; D017422:Sequence Analysis, DNA