title: Is ex vivo microdissection testicular sperm extraction indicated for infertile men undergoing radical orchiectomy for testicular cancer? Case report and literature review.
abstract: OBJECTIVE
  To report a case of an infertile man with nonobstructive azoospermia who underwent simultaneous radical orchiectomy for testicular cancer and testicular sperm extraction (TESE) for preservation of fertility.
  
  
  METHODS
  Case report and literature review.
  
  
  METHODS
  University teaching hospital.
  
  
  METHODS
  A couple being treated for infertility.
  
  
  METHODS
  Radical orchiectomy with simultaneous TESE.
  
  
  METHODS
  Sperm retrieval, histologic evaluation of archived testicular pathology slides.
  
  
  RESULTS
  We retrieved 20 spermatozoa from the multiple random TESE samples obtained at radical orchiectomy. Histologic evaluation of the archived testicular pathology slides revealed that the testis contained several foci of active spermatogenesis, suggesting that a significantly greater number of spermatozoa would likely have been retrieved had a microdissection TESE been performed instead of the multiple TESEs.
  
  
  CONCLUSIONS
  We propose that microdissection TESE should be considered the preferred sperm retrieval technique at the time of radical orchiectomy in men with coexistent nonobstructive azoospermia and testicular cancer.
authors: Division of Urology, Department of Surgery, McGill University Health Center, McGill University, Montreal, Quebec, Canada.
authors: Nicholas
authors: N
authors: Haddad
authors: Division of Urology, Department of Surgery, McGill University Health Center, McGill University, Montreal, Quebec, Canada.
authors: Khalid
authors: K
authors: Al-Rabeeah
authors: Division of Pathology, St. Mary's Hospital Center, Montreal, Quebec, Canada.
authors: Ronald
authors: R
authors: Onerheim
authors: Division of Urology, Department of Surgery, McGill University Health Center, McGill University, Montreal, Quebec, Canada. Electronic address: ziniarmand@yahoo.com.
authors: Armand
authors: A
authors: Zini
mesh_terms: D000328:Adult; D006801:Humans; D007248:Infertility, Male / Q000209:etiology / Q000473:pathology* / Q000534:rehabilitation*; D008297:Male; D042282:Microdissection / Q000379:methods*; D009919:Orchiectomy / Q000009:adverse effects / Q000379:methods*; D053625:Sperm Retrieval; D013736:Testicular Neoplasms / Q000150:complications* / Q000601:surgery*; D016896:Treatment Outcome
keywords: Cryopreservation; TESE; microTESE; nonobstructive azoospermia; testicular cancer