title: Asymmetric α-amination reaction of alkenyl trifluoroacetates catalyzed by a chiral phosphine-silver complex.
abstract: The asymmetric α-amination of alkenyl trifluoroacetates with dialkyl azodicarboxylates catalyzed by the DTBM-SEGPHOS·AgOTf complex takes place in the presence of 2,2,2-trifluoroethanol with almost quantitative yield and high ees of up to 97%.
authors: Department of Chemistry, Graduate School of Science, Chiba University, Inage, Chiba 263-8522, Japan. ayanagi@faculty.chiba-u.jp.
authors: Akira
authors: A
authors: Yanagisawa
authors: Ryoji
authors: R
authors: Miyake
authors: Kazuhiro
authors: K
authors: Yoshida
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D014269:Trifluoroacetic Acid / Q000737:chemistry*
chemical_list: D000475:Alkenes; D007659:Ketones; D009942:Organometallic Compounds; D010720:Phosphines; D012834:Silver; D014269:Trifluoroacetic Acid; C044646:phosphine