title: Tunable acid-sensitive ester protecting groups in oligosaccharide synthesis.
abstract: A series of acid-cleavable ester-type protecting groups, with acid-sensitivity profiles parallel to those of 2-naphthylmethyl (NAP) or p-methoxybenzyl (PMB) ether, were designed and TFA in toluene was identified as a technically simple and effective deblocking cocktail for their global removal in the context of oligosaccharide synthesis.
authors: Department of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, PA 15260, USA. xinyuliu@pitt.edu.
authors: Yao
authors: Y
authors: Li
authors: Xinyu
authors: X
authors: Liu
mesh_terms: D000143:Acids / Q000737:chemistry*; D004952:Esters / Q000737:chemistry*; D015394:Molecular Structure; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000143:Acids; D004952:Esters; D009844:Oligosaccharides