title: Pregnancies after transjugular intrahepatic portosystemic shunt for noncirrhotic portal hypertension.
abstract: With the growing role of transjugular intrahepatic portosystemic shunt (TIPS) in the management of portal hypertension complications, a number of women of childbearing age are now being treated with TIPS. However, if pregnancy is unusual in patients with cirrhosis, it can occur in the case of noncirrhotic portal hypertension. To our knowledge, there are no data on pregnancy safety after TIPS insertion. We report the first case of a patient with noncirrhotic portal hypertension treated by TIPS who had two successful pregnancies. She presented with HIV-associated obliterative portopathy with recurrent variceal bleeding treated by TIPS. Pregnancies occurred later and progressed normally without maternal or fetal morbidity. There was no effect on TIPS patency, but only a moderate increase in the flow velocity in the portal vein, the stent, and the hepatic artery. Thus, TIPS does not seem to impair progression of pregnancy.
authors: Departments of aHepatogastroenterology bUltrasound, Trousseau Hospital Departments of cInfectious Diseases dGynecology, Bretonneau Hospital, Tours, France.
authors: Charlotte
authors: C
authors: Nicolas
authors: Emma
authors: E
authors: Ferrand
authors: Louis
authors: L
authors: d'Alteroche
authors: Jean
authors: J
authors: Ayoub
authors: Frederic
authors: F
authors: Bastides
authors: Jerome
authors: J
authors: Potin
authors: Jean-Marc
authors: JM
authors: Perarnau
mesh_terms: D000328:Adult; D005260:Female; D015658:HIV Infections / Q000150:complications; D006801:Humans; D006975:Hypertension, Portal / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D050498:Live Birth; D019168:Portasystemic Shunt, Transjugular Intrahepatic; D011247:Pregnancy