title: Ethanol effect on batch and fed-batch Arthrospira platensis growth.
abstract: The ability of Arthrospira platensis to use ethanol as a carbon and energy source was investigated by batch process and fed-batch process. A. platensis was cultivated under the effect of a single addition (batch process) and a daily pulse feeding (fed-batch process) of pure ethanol, at different concentrations, to evaluate cell concentration (X) and specific growth rate (μ). A marked increase was observed in the cell concentration of A. platensis in runs with ethanol addition when compared to control cultures without ethanol addition. The fed-batch process using an ethanol concentration of 38 mg L(-1) days(-1) reached the maximum cell concentration of 2,393 ± 241 mg L(-1), about 1.5-fold that obtained in the control culture. In all experiments, the maximum specific growth rate was observed in the early exponential phase of cell growth. In the fed-batch process, μ decreased more slowly than in the batch process and control culture, resulting in the highest final cell concentration. Ethanol can be used as a feasible carbon and energy source for A. platensis growth via a fed-batch process.
authors: Department of Biochemical and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes 580 Bl. 16, São Paulo, SP, 05508-900, Brazil.
authors: Raquel P
authors: RP
authors: Bezerra
authors: Marcelo C
authors: MC
authors: Matsudo
authors: Lina S
authors: LS
authors: Pérez Mora
authors: Sunao
authors: S
authors: Sato
authors: João C Monteiro
authors: JC
authors: de Carvalho
mesh_terms: D061249:Batch Cell Culture Techniques; D018533:Biomass; D000458:Cyanobacteria / Q000254:growth & development* / Q000378:metabolism; D000431:Ethanol / Q000378:metabolism*
chemical_list: D000431:Ethanol