title: Frequency of precancerous changes and cervical cancer recorded in three health centres in tuzla canton in period 2010-2011.
abstract: Cervical cancer is the second most common cancer in the world and the leading cause of death. Frequency and mortality are significantly reduced thanks to cytological Papanicolau test (PAP). Regular PAP test can reduce approximately 80% of cases of this cancer.
  
  
  OBJECTIVE
  To examine frequency of cervical cancer and changes of cervix, the age of risk for the changes and effect of frequency of PAP test.
  
  
  METHODS
  3383 PAP (cytological) findings have been retrospectively ana lysed in three Health Centres of Tuzla Canton: Tuzla, Srebrenik and Sapna. During 2010 and 2011 protocols of Health Centers have been analyzed.
  
  
  RESULTS
  Analysis of 3383 smears detected the following: abnormal PAP tests in 20.8% (705) and without abnormalities in 79.1% (2678). Normal findings in 9.1% (311), inflammatory changes in 69.6% (2357), ASCUS in 12.9% (438), ASC-H in 0.3% (11), LSIL in 5.4% (183), HSIL in 1.4% (49) and Squamous cell carcinoma in 0.7% (24). Cervical cancer has mostly been found in women from Srebrenik 1.1% (15) and least in women from Tuzla 0.3%(4).The highest number of abnormal findings (ASCUS, ASC-H , LSIL, H SIL and Cc) was also found in women from Srebrenik 39.5% (279). The average age of the examinees with the cancer was 41.7. In 62.5% (15) of women PAP test was performed for the first time and they were diagnosed with cervical cancer. Cervical cancer hasn't been found in women who had PAP test once a year or more.
  
  
  CONCLUSIONS
  Women with the abnormal findings in their first PAP test and should be persuaded to accept the treatment in order to prevent development of cervical cancer.
authors: Gynecology Clinic "Dr Mahira Jahić" Tuzla Bosnia and Herzegovina.
authors: Mahira
authors: M
authors: Jahic
authors: Department of Microbiology, Polyclinic for Laboratory Diagnostics, University Clinical Center Tuzla, Bosnia and Herzegovina.
authors: Mirsada
authors: M
authors: Mulavdic
authors: Department of Gynecology and Obstetrics, University Clinical Center Tuzla, Bosnia and Herzegovina.
authors: Fatima
authors: F
authors: Dautbasic
authors: Department of Gynecology and Obstetrics, University Clinical Center Tuzla, Bosnia and Herzegovina.
authors: Mara
authors: M
authors: Fejzic
authors: Clinic for Cardiovascular Disease, Department of Interventional Cardiology, University Clinical Center Tuzla, Bosnia and Herzegovina.
authors: Elmir
authors: E
authors: Jahic
keywords: Cervical cancer; PAP test; Regular examination.