title: Optical coherence correlation spectroscopy (OCCS).
abstract: We present a new method called optical coherence correlation spectroscopy (OCCS) using nanoparticles as reporters of kinetic processes at the single particle level. OCCS is a spectral interferometry based method, thus giving simultaneous access to several sampling volumes along the optical axis. Based on an auto-correlation analysis, we extract the diffusion coefficients and concentrations of nanoparticles over a large concentration range. The cross-correlation analysis between adjacent sampling volumes allows to measure flow parameters. This shows the potential of OCCS for spatially resolved diffusion and flow measurements.
authors: Stephane
authors: S
authors: Broillet
authors: Akihiro
authors: A
authors: Sato
authors: Stefan
authors: S
authors: Geissbuehler
authors: Christophe
authors: C
authors: Pache
authors: Arno
authors: A
authors: Bouwens
authors: Theo
authors: T
authors: Lasser
authors: Marcel
authors: M
authors: Leutenegger
mesh_terms: D000465:Algorithms; D004058:Diffusion; D057054:Molecular Imaging / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*; D013057:Spectrum Analysis / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000379:methods*