title: ORGANOCOPPER-MEDIATED TWO-COMPONENTSN2'-SUBSTITUTION CASCADE TOWARDSN-FUSED HETEROCYCLES.
abstract: Organocuprates efficiently undergo reaction with heterocyclic propargyl mesylates at low temperature to produce N-fused heterocycles. The copper reagent plays a "double duty" in this cascade transformation, which proceeds through an SN2'-substitution followed by a consequent cycloisomerization step.
authors: University of Illinois at Chicago, 845 West Taylor St., Chicago 60607, Illinois, USA.
authors: D
authors: D
authors: Chernyak
authors: University of Illinois at Chicago, 845 West Taylor St., Chicago 60607, Illinois, USA.
authors: V
authors: V
authors: Gevorgyan
keywords: allenes; cycloisomerization; indolizines; propargyl mesylates; synthetic methods