title: Preliminary success in the characterization and management of a sudden breakout of a novel H7N9 influenza A virus.
abstract: Influenza has always been one of the major threats to human health. The Spanish influenza in 1918, the pandemic influenza A/H1N1 in 2009, and the avian influenza A/H5N1 have brought about great disasters or losses to mankind. More recently, a novel avian influenza A/H7N9 broke out in China and until December 2, 2013, it had caused 139 cases of infection, including 45 deaths. Its risk and pandemic potential attract worldwide attention. In this article, we summarize epidemiology, virology characteristics, clinical symptoms, diagnosis methods, clinical treatment and preventive measures about the avian influenza A/H7N9 virus infection to provide a reference for a possible next wave of flu outbreak.
authors: 1. Lab of Molecular Immunology, Virus Inspection Department, Zhejiang Provincial Center for Disease Control and Prevention, 630 Xincheng Road, Hangzhou, 310051, PR China.
authors: Yan-Ling
authors: YL
authors: Wu
authors: 2. Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou, 310014, PR China.
authors: Li-Wen
authors: LW
authors: Shen
authors: 1. Lab of Molecular Immunology, Virus Inspection Department, Zhejiang Provincial Center for Disease Control and Prevention, 630 Xincheng Road, Hangzhou, 310051, PR China. ; 2. Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou, 310014, PR China.
authors: Yan-Ping
authors: YP
authors: Ding
authors: 3. Center for Innovation in Immunoregulative Technology and Therapeutics, Graduate School of Medicine, Kyoto University, Kyoto, 606-8501, Japan.
authors: Yoshimasa
authors: Y
authors: Tanaka
authors: 2. Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou, 310014, PR China.
authors: Wen
authors: W
authors: Zhang
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use; D001717:Birds; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D005843:Geography; D006801:Humans; D064766:Influenza A Virus, H7N9 Subtype; D007252:Influenza Vaccines / Q000627:therapeutic use; D005585:Influenza in Birds; D007251:Influenza, Human / Q000453:epidemiology* / Q000628:therapy* / Q000821:virology*; D010802:Phylogeny; D016865:Reassortant Viruses; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D007252:Influenza Vaccines
keywords: H7N9 virus; avian influenza A; diagnosis; infection; prevention.; treatment