title: Reductive synthesis of aminal radicals for carbon-carbon bond formation.
abstract: Aminal radicals were generated by reduction of the corresponding amidine or amidinium ion. The intermediate radicals participate in C-C bond-forming reactions to produce fully substituted aminal stereocenters. No toxic additives or reagents are required. More than 30 substrate combinations are reported, and chemical yields are as high as 99%.
authors: Department of Chemistry, Oregon State University , 153 Gilbert Hall, Corvallis, Oregon 97331, United States.
authors: David A
authors: DA
authors: Schiedler
authors: Yi
authors: Y
authors: Lu
authors: Christopher M
authors: CM
authors: Beaudry
mesh_terms: D000578:Amidines / Q000138:chemical synthesis / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000578:Amidines; D002244:Carbon