title: Arterial elasticity, strength, fatigue, and endurance in older women.
abstract: Arterial health may influence muscle function in older adults. Study purpose was to determine whether arterial elasticity is related to strength, central and peripheral fatigue, fatigue at rest, and treadmill endurance. Subjects were 91 healthy women aged >60. Treadmill endurance and maximal oxygen uptake (VO2 max) were measured. Peripheral and central fatigue for the knee extensors were evaluated using two isometric fatigue tests (one voluntary and one adding electrical stimulation). Arterial elasticity was determined using radial artery pulse wave analysis. Linear multiple regression was used in statistical analysis. Large artery elasticity was associated with central fatigue (P < 0.01) and treadmill endurance (P < 0.02) after adjusting for VO2 max and knee extension strength. Subjective fatigue at rest was related to large artery elasticity after adjusting for ethnic origin (<0.02). Strength was significantly related to small artery elasticity after adjusting for ethnic origin, leg lean tissue, age, and blood pressure. Arterial elasticity is independently related to strength and fatigue in older women, especially in the central nervous system where arterial elasticity is independently related to perceptions of fatigue at rest and central fatigue. These results suggest that arterial health may be involved with the ability of the central nervous system to activate muscle in older women.
authors: Department of Human Studies, University of Alabama at Birmingham, Birmingham, AL 35294, USA ; Department of Nutrition Science, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
authors: Gary R
authors: GR
authors: Hunter
authors: Department of Psychology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
authors: William H
authors: WH
authors: Neumeier
authors: Department of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
authors: C Scott
authors: CS
authors: Bickel
authors: Department of Human Movement Sciences, Carroll University, Waukesha, WI 53186, USA.
authors: John P
authors: JP
authors: McCarthy
authors: Department of Human Studies, University of Alabama at Birmingham, Birmingham, AL 35294, USA ; Department of Nutrition Science, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
authors: Gordon
authors: G
authors: Fisher
authors: Department of Nutrition Science, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
authors: Paula C
authors: PC
authors: Chandler-Laney
authors: Department of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
authors: Stephen P
authors: SP
authors: Glasser
mesh_terms: D001741:Black or African American; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000473:pathology*; D001158:Arteries / Q000503:physiopathology*; D001794:Blood Pressure; D004548:Elasticity; D005260:Female; D006801:Humans; D053580:Muscle Strength / Q000502:physiology*; D010807:Physical Endurance; D044465:White People