title: Total synthesis of asterredione.
abstract: The first total synthesis of asterredione was efficiently accomplished over five linear steps and in 21.5% overall yield. As the crucial step, the 2-quaternary 1,3-cyclopentenedione skeleton of asterredione was readily achieved using the Darzens/ring-expansion strategy developed in our laboratory. The structure of synthesized asterredione was fully confirmed by X-ray crystallography.
authors: Department of Chemistry & Material Science, Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education of China, Northwest University , Xi'an 710069, China.
authors: Sinan
authors: S
authors: Gai
authors: Qing
authors: Q
authors: Zhang
authors: Xiangdong
authors: X
authors: Hu
mesh_terms: D018360:Crystallography, X-Ray; D003517:Cyclopentanes / Q000138:chemical synthesis / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D003517:Cyclopentanes; D007211:Indoles; C482764:asterredione