title: Aggregatibacter aphrophilus brain abscess secondary to primary tooth extraction: Case report and literature review.
abstract: We report on a rare case of Aggregatibacter aphrophilus brain abscess of odontogenic origin in a 6-year-old previously healthy boy, who had close contact with a pet dog. The poodle was the most likely source of the infecting organism, which subsequently colonized the patient's oral cavity. The abscess was surgically removed and he recovered completely after prolonged antibiotic treatment with meropenem. We also review the relevant medical literature on A. aphrophilus pediatric brain abscesses.
authors: Department of Clinical Microbiology, Parasitology, Zoonoses and Geographical Medicine, University Hospital of Heraklion, Heraklion, Crete, Greece. Electronic address: sofiamaraki@yahoo.gr.
authors: Sofia
authors: S
authors: Maraki
authors: Department of Clinical Microbiology, Parasitology, Zoonoses and Geographical Medicine, University Hospital of Heraklion, Heraklion, Crete, Greece.
authors: Ioannis S
authors: IS
authors: Papadakis
authors: Department of Neurosurgery, University Hospital of Heraklion, Heraklion, Crete, Greece.
authors: Efkleidis
authors: E
authors: Chronakis
authors: Department of Neurosurgery, University Hospital of Heraklion, Heraklion, Crete, Greece.
authors: Dimitrios
authors: D
authors: Panagopoulos
authors: Department of Neurosurgery, University Hospital of Heraklion, Heraklion, Crete, Greece.
authors: Antonis
authors: A
authors: Vakis
mesh_terms: D064207:Aggregatibacter aphrophilus / Q000302:isolation & purification*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001922:Brain Abscess / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D002648:Child; D003646:Debridement; D004285:Dogs; D006801:Humans; D008297:Male; D016871:Pasteurellaceae Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D014081:Tooth Extraction / Q000009:adverse effects*; D014094:Tooth, Deciduous; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents
keywords: Aggregatibacter aphrophilus; Brain abscess; Canine transmission; Odontogenic origin