title: Peptides-staple method development and its application in cancer therapy.
abstract: α-Helixes are important structural motifs of protein three dimension structures and are largely involved in protein- protein interactions. This review covers the recent advances of the peptide stabilizing methodologies and introduces their applications in cancer research.
authors: Q Z
authors: QZ
authors: Zhang
authors: Y
authors: Y
authors: Tian
authors: Y Z
authors: YZ
authors: Lao
authors: School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, Guangdong, 518055, P. R. China. lizg@pkusz.edu.cn.
authors: Z-G
authors: ZG
authors: Li
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D055808:Drug Discovery / Q000379:methods*; D006801:Humans; D008969:Molecular Sequence Data; D009369:Neoplasms / Q000188:drug therapy*; D010455:Peptides / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D055550:Protein Stability; D017433:Protein Structure, Secondary
chemical_list: D010455:Peptides