title: Esophageal manometry in gastroesophageal reflux disease.
abstract: High-resolution manometry (HRM) allows nuanced evaluation of esophageal motor function, and more accurate evaluation of lower esophageal sphincter (LES) function, in comparison with conventional manometry. Pathophysiologic correlates of gastroesophageal reflux disease (GERD) and esophageal peristaltic performance are well addressed by this technique. HRM may alter the surgical decision by assessment of esophageal peristaltic function and exclusion of esophageal outflow obstruction before antireflux surgery. Provocative testing during HRM may assess esophageal smooth muscle peristaltic reserve and help predict the likelihood of transit symptoms following antireflux surgery. HRM represents a continuously evolving new technology that compliments the evaluation and management of GERD.
authors: Division of Gastroenterology, Washington University School of Medicine, Campus Box 8124, 660 South Euclid Avenue, St Louis, MO 63110, USA.
authors: Michael
authors: M
authors: Mello
authors: Division of Gastroenterology, Washington University School of Medicine, Campus Box 8124, 660 South Euclid Avenue, St Louis, MO 63110, USA. Electronic address: cprakash@wustl.edu.
authors: C Prakash
authors: CP
authors: Gyawali
mesh_terms: D049630:Esophageal Sphincter, Lower / Q000503:physiopathology; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008365:Manometry / Q000379:methods*; D010528:Peristalsis / Q000502:physiology; D011300:Preoperative Care
keywords: Esophageal hypomotility; High-resolution manometry; Hypotensive lower esophageal sphincter; Multiple rapid swallows; Preoperative testing