title: Highly chemo-, regio-, and enantioselective rhodium-catalyzed cross-cyclotrimerization of two different alkynes with alkenes.
abstract: It has been established that a cationic rhodium(I)/(R)-tol-binap complex catalyzes the cross-cyclotrimerization of silylacetylenes, di-tert-butyl acetylenedicarboxylates, and acrylamides with excellent chemo-, regio-, and enantioselectivities. Unsymmetrical alkynoates can also be employed in place of di-tert-butyl acetylenedicarboxylate for this process, but with reduced chemoselectivity.
authors: Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588 (Japan) http://www.tuat.ac.jp/∼tanaka-k/
authors: Jun
authors: J
authors: Hara
authors: Mana
authors: M
authors: Ishida
authors: Masayuki
authors: M
authors: Kobayashi
authors: Keiichi
authors: K
authors: Noguchi
authors: Ken
authors: K
authors: Tanaka
keywords: alkenes; alkynes; asymmetric catalysis; cyclotrimerization; multicomponent reactions; rhodium