title: Vitamin D insufficiency is associated with abdominal obesity in urban Asian Indians without diabetes in North India.
abstract: OBJECTIVE
  We evaluated the associations of serum 25-hydroxyvitamin D [25(OH) D] levels with clinical, biochemical, and anthropometric profiles and total abdominal adipose tissue (TAAT), subcutaneous abdominal adipose tissue (SCAT), and intraabdominal adipose tissue (IAAT) depots in Asian Indians without diabetes residing in north India.
  
  
  METHODS
  In this cross-sectional study (n=137; 74 males and 63 females; 18-60 years of age), anthropometric (body mass index, waist and hip circumferences, and skinfold thickness at four sites) and biochemical (fasting plasma glucose, lipid profile, and fasting insulin levels) assessments were done. Measurement of percentage body fat was done by dual energy x-ray absorptiometry, and areas of TAAT, SCAT and IAAT were measured at the L2-L3 intervertebral level by single-slice magnetic resonance imaging. Levels of 25(OH) D were measured by radioimmunoassay. Correlation analysis was used to assess relationships among clinical, biochemical, and anthropometric profiles, areas of TAAT, SCAT, and IAAT, and 25(OH) D levels.
  
  
  RESULTS
  The mean concentration of 25(OH) D was 40.5 ± 8.6 ng/mL. Overall, 6.6% had vitamin D deficiency (<10 ng/mL), 87.6% had insufficiency (<30 ng/mL), and 5.8% had a sufficient level (>30 ng/mL). Levels of 25(OH) D did not correlate with demographic, biochemical, and anthropometric profiles or with abdominal fat depots (TAAT, SCAT, and IAAT). In the correlation regression model, 25(OH) D was associated with TAAT in obese subjects.
  
  
  CONCLUSIONS
  In obese urban Asian Indians without diabetes, higher values of total abdominal fat at the L2-L3 intervertebral level were associated with low 25(OH) D levels.
authors: 1 Department of Medicine, All India Institute of Medical Sciences , New Delhi, India .
authors: Surya Prakash
authors: SP
authors: Bhatt
authors: Anoop
authors: A
authors: Misra
authors: Mukti
authors: M
authors: Sharma
authors: Randeep
authors: R
authors: Guleria
authors: Ravindra Mohan
authors: RM
authors: Pandey
authors: Kalpana
authors: K
authors: Luthra
authors: Naval Kishore
authors: NK
authors: Vikram
mesh_terms: D050153:Abdominal Fat / Q000473:pathology*; D015502:Absorptiometry, Photon; D000293:Adolescent; D000328:Adult; D001823:Body Composition; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D056128:Obesity, Abdominal / Q000097:blood / Q000453:epidemiology* / Q000208:ethnology / Q000473:pathology; D012307:Risk Factors; D012885:Skinfold Thickness; D014505:Urban Population; D014808:Vitamin D Deficiency / Q000097:blood / Q000453:epidemiology* / Q000208:ethnology; D044465:White People