title: Brain development in preterm infants assessed using advanced MRI techniques.
abstract: Infants who are born preterm have a high incidence of neurocognitive and neurobehavioral abnormalities, which may be associated with impaired brain development. Advanced magnetic resonance imaging (MRI) approaches, such as diffusion MRI (d-MRI) and functional MRI (fMRI), provide objective and reproducible measures of brain development. Indices derived from d-MRI can be used to provide quantitative measures of preterm brain injury. Although fMRI of the neonatal brain is currently a research tool, future studies combining d-MRI and fMRI have the potential to assess the structural and functional properties of the developing brain and its response to injury.
authors: Centre for the Developing Brain, Department of Perinatal Imaging, St Thomas' Hospital, King's College London, Westminster Bridge Road, London SE1 7EH, UK.
authors: Nora
authors: N
authors: Tusor
authors: Centre for the Developing Brain, Department of Perinatal Imaging, St Thomas' Hospital, King's College London, Westminster Bridge Road, London SE1 7EH, UK; Department of Bioengineering, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
authors: Tomoki
authors: T
authors: Arichi
authors: Centre for the Developing Brain, Department of Perinatal Imaging, St Thomas' Hospital, King's College London, Westminster Bridge Road, London SE1 7EH, UK.
authors: Serena J
authors: SJ
authors: Counsell
authors: Centre for the Developing Brain, Department of Perinatal Imaging, St Thomas' Hospital, King's College London, Westminster Bridge Road, London SE1 7EH, UK; Department of Bioengineering, Imperial College London, South Kensington Campus, London SW7 2AZ, UK. Electronic address: ad.edwards@kcl.ac.uk.
authors: A David
authors: AD
authors: Edwards
mesh_terms: D001921:Brain / Q000254:growth & development / Q000473:pathology* / Q000503:physiopathology; D001930:Brain Injuries / Q000473:pathology* / Q000503:physiopathology; D002540:Cerebral Cortex / Q000254:growth & development / Q000473:pathology / Q000503:physiopathology; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D056324:Diffusion Tensor Imaging / Q000379:methods; D059907:Functional Neuroimaging / Q000379:methods; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009434:Neural Pathways / Q000254:growth & development / Q000473:pathology* / Q000503:physiopathology; D013788:Thalamus / Q000254:growth & development / Q000473:pathology / Q000503:physiopathology
keywords: Brain; Diffusion-MRI; Functional MRI; MRI; Preterm