title: Desferrioxamine treatment of porphyria cutanea tarda in a patient with HIV and chronic renal failure.
abstract: Porphyria cutanea tarda (PCT) can occur in HIV patients. Current evidence suggests that HIV infection may interfere with the hepatic cytochrome oxidase system, leading to porphyrin metabolism impairment. Moreover, chronic hemodialysis in renal failure may be a risk factor for PCT. In addition to the contributory factors for PCT associated to HIV infection, it is possible that porphyrin accumulation secondary to renal failure may play a role in the expression of this disease. We report a case of PCT in an HIV-1 infected patient under blood dialysis, refractory to antimalarials and controlled with desferrioxamine.
authors: Dermatology University Clinic, Hospital de Santa Maria, Serviço de Dermatologia, Lisboa, Portugal.
authors: Pedro
authors: P
authors: Vasconcelos
authors: H
authors: H
authors: Luz-Rodrigues
authors: Carla
authors: C
authors: Santos
authors: Paulo
authors: P
authors: Filipe
mesh_terms: D003676:Deferoxamine / Q000627:therapeutic use*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008875:Middle Aged; D017119:Porphyria Cutanea Tarda / Q000188:drug therapy*
chemical_list: D003676:Deferoxamine
keywords: HIV; chronic renal failure; porphyria cutanea tarda