title: Convergence of advances in genomics, team science, and repositories as drivers of progress in psychiatric genomics.
abstract: After many years of unfilled promise, psychiatric genetics has seen an unprecedented number of successes in recent years. We hypothesize that the field has reached an inflection point through a confluence of four key developments: advances in genomics; the orientation of the scientific community around large collaborative team science projects; the development of sample and data repositories; and a policy framework for sharing and accessing these resources. We discuss these domains and their effect on scientific progress and provide a perspective on why we think this is only the beginning of a new era in scientific discovery.
authors: National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland. Electronic address: Tlehner@mail.nih.gov.
authors: Thomas
authors: T
authors: Lehner
authors: National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
authors: Geetha
authors: G
authors: Senthil
authors: National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
authors: Anjené M
authors: AM
authors: Addington
mesh_terms: D001689:Biological Psychiatry / Q000379:methods* / Q000639:trends*; D003299:Cooperative Behavior; D030541:Databases, Genetic; D023281:Genomics; D006801:Humans
keywords: Biosamples; Data Sharing; NIMH Repository and Genomics Resource; Psychiatric Genomics; Team Science; dbGaP