title: Chemical composition, antimicrobial and antioxidant activities of essential oil from Ampelopsis megalophylla.
abstract: Chemical composition, antimicrobial and antioxidant activities of the essential oil of Ampelopsis megalophylla were evaluated in this research. GC-MS analysis of the essential oil revealed 42 compounds, representing 88.54% of the oil. The major compounds were borneol (10.81%), α-pinene (6.74%) and β-elemene (6.23%). The antimicrobial activity of the essential oil was evaluated against 13 micro-organisms using the disc diffusion and broth microdilution methods. Results demonstrated higher effects of this oil against Gram-positive bacteria than the other reference strains tested. The antioxidant effect of the essential oil was evaluated by using 1,1-Diphenyl-2-picrylhydrazyl (DPPH) and 2,20-azinobis-3-ethylbenzthiazoline-6-sulfonate scavenging assays. The essential oil exhibited moderate antioxidant activity.
authors: a Department of Pharmacology , Basic Medical School, Wuhan University , Wuhan 430072 , P.R. China.
authors: Xian-Fei
authors: XF
authors: Xie
authors: Jian-Wu
authors: JW
authors: Wang
authors: Han-Ping
authors: HP
authors: Zhang
authors: Qi-Xiong
authors: QX
authors: Li
authors: Bang-Yin
authors: BY
authors: Chen
mesh_terms: D032421:Ampelopsis / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000081008:Bicyclic Monoterpenes; D001713:Biphenyl Compounds / Q000494:pharmacology; D001892:Camphanes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D008401:Gas Chromatography-Mass Spectrometry; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry*; D010851:Picrates / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D000081008:Bicyclic Monoterpenes; D001713:Biphenyl Compounds; D001892:Camphanes; D039821:Monoterpenes; D009822:Oils, Volatile; D010851:Picrates; D010938:Plant Oils; D012717:Sesquiterpenes; C445979:beta-elemene; C004931:1,1-diphenyl-2-picrylhydrazyl; C005451:alpha-pinene; C022871:isoborneol
keywords: Ampelopsis megalophylla; GC–MS; antimicrobial; antioxidant; essential oil