title: [Apocrine breast cancer in the material from Cancer Centre in Krakow. Clinical features and treatment results in patients treated between 1952 and 2002].
abstract: Apocrine breast cancer is a rare type of neoplasm and accounts for approximately 0.3-4% of all breast cancers. It most frequently diagnosed in women over the age of 50.
  
  
  OBJECTIVE
  The purpose of the study was to present the clinical characteristics and treatment outcomes of 53 patients treated from apocrine breast cancer at the Oncology Center in Kraków between 1955 and 2002..
  
  
  METHODS
  Stage I or II carcinomas were found in 37 patients (69.8%) of the study group and 16 patients (30.2%) were classified as stage II. Node metastases were observed in 27 patients (50.9%). Surgery constituted the primary method of treatment and was used in all patients. Forty-nine patients underwent mastectomy and 4 underwent breast conserving surgery Post-operative radiotherapy was given to 16 patients. Chemotherapy and hormonal therapy were also used--in 20 and 26 cases, respectively.
  
  
  RESULTS
  The follow-up period in the study group was maximum 207 months. The 10-year survival rates were as follows: 75.9% (overall survival) and 58.1% (disease-free survival). It was shown that positive lymph nodes highly affected symptoms-free free survival. During follow-up, 7 patients developed local recurrence, 16 patients developed distant metastases. Second primary malignancies were found in 5 patients.
  
  
  CONCLUSIONS
  Our findings confirm good prognosis in patients treated for apocrine breast cancer similar to invasive ductal carcinoma.
authors: Klinika Onkologii, Oddział Nowotworów Piersi i Klati Piersiowej, Centrum Onkologii, Instytut im Marii Skłodowskiej-Curie Oddział w Krakowie, Polska. z5korczy@cyf-kr.edu.pl
authors: Beata
authors: B
authors: Sas-Korczyńska
authors: Klinika Chirurgii Onkologicznej, Centrum Onkologii, Instytut im Marii Skłodowskiej-Curie Oddział w Krakowie, Polska.
authors: Jerzy
authors: J
authors: Mituś
authors: Klinika Chirurgii Onkologicznej, Centrum Onkologii, Instytut im Marii Skłodowskiej-Curie Oddział w Krakowie, Polska.
authors: Andrzej
authors: A
authors: Stelmach
authors: Zakład Patologii Nowotworów, Centnum Onkologii, Instytut im Marii Skłodowskiej-Curie Oddział w Krakowie, Polska.
authors: Janusz
authors: J
authors: Ryś
authors: Klinika Onkologii, Oddział Nowotworów Piersi i Klati Piersiowej, Centrum Onkologii, Instytut im Marii Skłodowskiej-Curie Oddział w Krakowie, Polska.
authors: Dariusz
authors: D
authors: Martynów
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011044:Poland / Q000453:epidemiology; D011379:Prognosis; D015996:Survival Rate; D016896:Treatment Outcome