title: Antibodies against Duvenhage virus in insectivorous bats in Swaziland.
abstract: Several rabies-related lyssaviruses have been associated with bat species in southern Africa, the rarest of these being Duvenhage virus (DUVV), for which only five isolations have been made over five decades. Three of these were from human fatalities, and it is not known which bat species acts as reservoir. In studying a population of Nycteris thebaica in the kingdom of Swaziland, a landlocked country bordering Mozambique and South Africa, we found evidence of the circulation of a lyssavirus. Virus-neutralization assays indicated DUVV-neutralizing antibodies in 30% of the sera collected from this population of N. thebaica, providing the first indication of a Duvenhage virus circulating in this particular species and the first evidence of a bat lyssavirus circulating in Swaziland bats.
authors: 1  Department of Microbiology and Plant Pathology, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria 0001, South Africa.
authors: Wanda
authors: W
authors: Markotter
authors: Ara
authors: A
authors: Monadjem
authors: Louis H
authors: LH
authors: Nel
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002685:Chiroptera / Q000097:blood*; D013541:Eswatini / Q000453:epidemiology; D005247:Feeding Behavior; D018114:Lyssavirus / Q000276:immunology*; D018353:Rhabdoviridae Infections / Q000097:blood / Q000453:epidemiology / Q000276:immunology / Q000662:veterinary*
chemical_list: D000914:Antibodies, Viral