title: [Superficial acral fibromyxoma in a sub-matricial location: An unusual variant].
abstract: BACKGROUND
  Superficial acral fibromyxoma (SAFM) is a benign soft tissue tumor located in the acral areas, particularly the peri- and sub-ungueal areas. Sub-matricial localisations have not been reported to date.
  
  
  METHODS
  We report herein the clinical and pathological presentation of three cases of SAFM located solely under the matrix. The patients presented with pseudo-clubbing, onychogryphosis or triangular macrolunula. The histopathological appearance was characteristic.
  
  
  CONCLUSIONS
  SAFM is a slow-growing, skin-colored, firm nodule, located chiefly on the digits or the toes, and especially in the nail area. It may or may not be painful. Microscopically, it presents as a relatively well-circumscribed but unencapsulated dermal tumor, composed of spindle shaped cells integrated in a myxocollagenic matrix, sometimes invading the subcutis. Tumor cells diffusely express CD34. A conservative surgical approach is recommended. Both clinicians and pathologists should be aware of this entity in order to avoid misdiagnosis, which can lead to unwarranted mutilating surgery.
  
  
  CONCLUSIONS
  Sub-matricial localisation of SAFM is extremely rare and may present as pseudo-clubbing, isolated onychogryphosis or a triangular macrolunula. A conservative surgical approach should be recommended.
authors: Service de dermatologie, CHU Ibn Rochd, 1, rue des Hôpitaux, 20360 Casablanca, Maroc.
authors: F
authors: F
authors: Chabbab
authors: Département inter-hospitalier de dermatologie-vénéréologie, CHU Brugmann, Saint-Pierre et hôpital universitaire des enfants Reine-Fabiola, université libre de Bruxelles, 4, place Van-Gehuchten, 1020 Bruxelles, Belgique.
authors: T
authors: T
authors: Metz
authors: Département inter-hospitalier de dermatologie-vénéréologie, CHU Brugmann, Saint-Pierre et hôpital universitaire des enfants Reine-Fabiola, université libre de Bruxelles, 4, place Van-Gehuchten, 1020 Bruxelles, Belgique.
authors: L
authors: L
authors: Saez Beltran
authors: Département inter-hospitalier de dermatologie-vénéréologie, CHU Brugmann, Saint-Pierre et hôpital universitaire des enfants Reine-Fabiola, université libre de Bruxelles, 4, place Van-Gehuchten, 1020 Bruxelles, Belgique; Département d'anatomie pathologique, Bordet Cancer Institute, université libre de Bruxelles, 121, boulevard de Waterloo, 1000 Bruxelles, Belgique.
authors: A
authors: A
authors: Theunis
authors: Département inter-hospitalier de dermatologie-vénéréologie, CHU Brugmann, Saint-Pierre et hôpital universitaire des enfants Reine-Fabiola, université libre de Bruxelles, 4, place Van-Gehuchten, 1020 Bruxelles, Belgique. Electronic address: bertrand.richert@chu-brugmann.be.
authors: B
authors: B
authors: Richert
mesh_terms: D000328:Adult; D018952:Antigens, CD34; D014408:Biomarkers, Tumor; D003937:Diagnosis, Differential; D005260:Female; D005350:Fibroma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005385:Fingers; D006801:Humans; D008067:Lipoma / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009260:Nail Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009442:Neurilemmoma / Q000175:diagnosis; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000209:etiology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014034:Toes
chemical_list: D018952:Antigens, CD34; D014408:Biomarkers, Tumor
keywords: Fibromyxome acral superficiel; Nail; Nail tumor; Ongle; Soft tissue tumor; Superficial acral fibromyxoma; Tumeur des tissus mous; Tumeur unguéale