title: The role of lymphadenectomy in uterine sarcoma: a clinical practical approach based on retrospective analysis.
abstract: BACKGROUND
  Uterine sarcomas are rare, highly aggressive tumors with an unfavorable prognosis. Only limited data on treatment and outcome are available and the role of lymphadenectomy is controversial for this particular tumor type.
  
  
  METHODS
  By performing a retrospective analysis, through clinical practice, we analyzed the impact of lymphadenectomy on patient outcome.
  
  
  RESULTS
  Out of 52 patients, 48 women underwent surgical treatment. Among those, lymphadenectomy was performed in 58%. 10% underwent pelvic and paraaortic lymphadenectomy and 48% underwent pelvic lymphadenectomy alone.
  
  
  CONCLUSIONS
  In our cohort, surgeons tended to perform paraaortic-plus-pelvic or pelvic-alone lymphadenectomy irrespective of the presence or absence of enlarged lymph nodes. Patients who underwent lymphadenectomy showed a better survival. This observation might indicate a potential role for systematic lymphadenectomy in the surgical treatment of uterine sarcoma. We review on clinical operative decisions, critically with regard to current evidence.
authors: Department of Gynaecology and Obstetrics, University of Schleswig-Holstein, Campus Luebeck. Ratzeburger Allee 160, 23538 Luebeck, Germany. friederike.hoellen@uksh.de.
authors: Friederike
authors: F
authors: Hoellen
authors: Anika
authors: A
authors: Waldmann
authors: Stephanie
authors: S
authors: Benthin
authors: Lars
authors: L
authors: Hanker
authors: Achim
authors: A
authors: Rody
authors: Dorothea
authors: D
authors: Fischer
mesh_terms: D018195:Adenosarcoma / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002296:Carcinosarcoma / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology / Q000601:surgery*; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology / Q000601:surgery; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery*
keywords: Sarcoma; carcinosarcoma; leiomyosarcoma; lymphadenectomy; uterine cancer