title: Laparoscopic myomectomy: a 6-year follow-up single-center cohort analysis of fertility and obstetric outcome measures.
abstract: OBJECTIVE
  To evaluate fertility, pregnancy and delivery outcomes after laparoscopic myomectomy (LM) during long-term follow-up.
  
  
  METHODS
  In this single-center retrospective observational study, data were analyzed from 59 women aged 23-42 years with the desire to have children and who underwent LM for symptomatic uterine leiomyoma between January 2001 and December 2006 and subsequently delivered at our hospital.
  
  
  RESULTS
  During a mean follow-up period of 73.55 months, the post-LM conception rate was 68 %. The proportion of miscarriages (n = 16) among all pregnancies (n = 55) was lower after (24 %) than before (43 %) LM. Thirty-nine (46 %) deliveries were primary cesarean sections (CSs). CS was performed due to patients' preference, placental complications, and uterine rupture (UR). Labor was successful in 62 % of all vaginal delivery trials. UR and placental complications occurred in 10 and 13 % of all pregnancies, respectively.
  
  
  CONCLUSIONS
  LM reduced the abortion rate and increased the CS rate in our cohort. UR risk may have been affected by suturing technique, the size and location of myomas removed.
authors: Department of Gynecology and Obstetrics, Jena University Hospital, Bachstraße 18, 07743, Jena, Germany.
authors: Tina Sybille
authors: TS
authors: Bernardi
authors: Marc Philipp
authors: MP
authors: Radosa
authors: Anja
authors: A
authors: Weisheit
authors: Herbert
authors: H
authors: Diebolder
authors: Uwe
authors: U
authors: Schneider
authors: Ekkehard
authors: E
authors: Schleussner
authors: Ingo Bernard
authors: IB
authors: Runnebaum
mesh_terms: D000022:Abortion, Spontaneous / Q000601:surgery; D000328:Adult; D002585:Cesarean Section; D036861:Delivery, Obstetric; D005260:Female; D005298:Fertility; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D007889:Leiomyoma / Q000150:complications / Q000601:surgery*; D017063:Outcome Assessment, Health Care; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D063186:Uterine Myomectomy / Q000009:adverse effects*; D014594:Uterine Neoplasms / Q000150:complications / Q000601:surgery; D014597:Uterine Rupture / Q000601:surgery