title: Stability and encapsulation efficiency of sulforaphane microencapsulated by spray drying.
abstract: Sulforaphane (SF) has received much attention because of its anticarcinogenic, antioxidant and anti-inflammatory properties, but it is quite unstable. Microencapsulation is one way to improve its stability. The aim of this work was to produce microcapsules containing sulforaphane using a spray drying technique. The effects of different wall materials, inlet air temperature and core to wall ratio on the SF stability, encapsulation efficiency, encapsulation yield, moisture content and SF content were determined. The results indicated that optimal encapsulation conditions for SF were: maltodextrin for the wall material, 170 °C for the inlet air temperature and 1:20 for the core/wall ratio. Characterization study showed that the microcapsules had a regular spherical shape. The stability of SF in spray dried microcapsules was greatly enhanced compared with that of free SF.
authors: School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, Zhejiang, China; Zhejiang Provincial Key Lab for Chem & Bio Processing Technology of Farm Produces, Hangzhou 310023, Zhejiang, China. Electronic address: wyfhz@126.com.
authors: Yuanfeng
authors: Y
authors: Wu
authors: Hangzhou Academy of Agricultural Sciences, Hanzhou 310024, China. Electronic address: jgszlg@163.com.
authors: Ligen
authors: L
authors: Zou
authors: School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, Zhejiang, China; Zhejiang Provincial Key Lab for Chem & Bio Processing Technology of Farm Produces, Hangzhou 310023, Zhejiang, China. Electronic address: zjhzmjw@163.com.
authors: Jianwei
authors: J
authors: Mao
authors: School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, Zhejiang, China; Zhejiang Provincial Key Lab for Chem & Bio Processing Technology of Farm Produces, Hangzhou 310023, Zhejiang, China. Electronic address: hjunlzr@163.com.
authors: Jun
authors: J
authors: Huang
authors: School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, Zhejiang, China; Zhejiang Provincial Key Lab for Chem & Bio Processing Technology of Farm Produces, Hangzhou 310023, Zhejiang, China. Electronic address: shiwangliu@163.com.
authors: Shiwang
authors: S
authors: Liu
mesh_terms: D016588:Anticarcinogenic Agents / Q000737:chemistry*; D004339:Drug Compounding; D017879:Isothiocyanates / Q000737:chemistry*; D007700:Kinetics; D008855:Microscopy, Electron, Scanning; D017550:Spectroscopy, Fourier Transform Infrared; D013454:Sulfoxides
chemical_list: D016588:Anticarcinogenic Agents; D017879:Isothiocyanates; D013454:Sulfoxides; C016766:sulforaphane
keywords: Encapsulation efficiency; Microencapsulation; Spray drying; Stability; Sulforaphane