title: Pure laparoscopic liver resection reduces surgical site infections and hospital stay. Results of a case-matched control study in 50 patients.
abstract: BACKGROUND
  Laparoscopic resection is an emerging tool in surgical oncology, but its role in liver tumors is far from being universally accepted.
  
  
  METHODS
  We designed a case-matched control study, comparing laparoscopic (LAP) vs. open hepatectomies (OP) performed in the same center during the same period of time. Fifty LAP were performed (34 liver metastases, 7 hepatocellular carcinomas, 2 hydatid cysts, and 5 benign tumors). Cases were compared with 100 OP matched according to: diagnosis, number of lesions, type of resection, age, ASA score, and ECOG performance status. We evaluated intraoperative and postoperative parameters, focusing on morbidity and mortality.
  
  
  RESULTS
  Preoperative data were comparable in both groups. Operative features were similar in terms of overall morbidity 18 (36 %) vs. 36 (36 %), p = 1; intraoperative bleeding, 401 (18-2192) vs. 475 (20-2000) mL, p = 0.89; pedicle clamping, 37 (74 %) vs. 88 (88 %), p = 0.55; margin, 0.6 (0-5) vs. 0.65 (0-5) cm, p = 0.94, and mortality p = 0.65 for the LAP and OP groups, respectively. There was a significant decrease in surgical site infections 1 (2 %) vs. 18 (18 %) p = 0.007 in the LAP group. Operative time was longer: 295 (120-600) vs. 200 (70-450) min (p = 0.0001), and hospital stay significantly shorter: 4 (1-60) vs. 7 (3-44) days, p = 0.0001 with less readmissions (0 vs. 7 %) in the LAP.
  
  
  CONCLUSIONS
  In adequately selected patients, laparoscopic hepatectomy is feasible, safe, shortens hospital stay, and decreases surgical site infections.
authors: Hepato-biliary and Pancreatic Surgery Unit, Department of Surgery, "Doctor Josep Trueta" Hospital, Biomedical Institute of Research, IdIBGi, Girona, Spain, santilb@msn.com.
authors: Santiago
authors: S
authors: López-Ben
authors: Oscar
authors: O
authors: Palacios
authors: Antonio
authors: A
authors: Codina-Barreras
authors: M Teresa
authors: MT
authors: Albiol
authors: Laia
authors: L
authors: Falgueras
authors: Ernesto
authors: E
authors: Castro
authors: Joan
authors: J
authors: Figueras
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D006498:Hepatectomy; D006801:Humans; D010535:Laparoscopy; D007902:Length of Stay; D008107:Liver Diseases / Q000150:complications / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010359:Patient Readmission; D013530:Surgical Wound Infection / Q000517:prevention & control*; D016896:Treatment Outcome