title: Safety and efficacy of adding sitagliptin to insulin in patients with type 2 diabetes: the ASSIST-K study.
abstract: We retrospectively studied more than 1000 patients with type 2 diabetes attending 36 Japanese clinics to investigate the efficacy and safety of adding sitagliptin to various insulin regimens. We found that the treatment with add-on sitagliptin for 6-months was effective, irrespective of the type or dose of concomitant insulin.
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Masahiko
authors: M
authors: Takai
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Masashi
authors: M
authors: Ishikawa
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Hajime
authors: H
authors: Maeda
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Akira
authors: A
authors: Kanamori
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Akira
authors: A
authors: Kubota
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Hikaru
authors: H
authors: Amemiya
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Takashi
authors: T
authors: Iizuka
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Kotaro
authors: K
authors: Iemitsu
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Tomoyuki
authors: T
authors: Iwasaki
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Goro
authors: G
authors: Uehara
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Shinichi
authors: S
authors: Umezawa
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Mitsuo
authors: M
authors: Obana
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Hideaki
authors: H
authors: Kaneshige
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Mizuki
authors: M
authors: Kaneshiro
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Takehiro
authors: T
authors: Kawata
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Nobuo
authors: N
authors: Sasai
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Tatsuya
authors: T
authors: Saito
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Tetsuo
authors: T
authors: Takuma
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Hiroshi
authors: H
authors: Takeda
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Keiji
authors: K
authors: Tanaka
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Nobuaki
authors: N
authors: Tsurui
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Shigeru
authors: S
authors: Nakajima
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Kazuhiko
authors: K
authors: Hoshino
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Shin
authors: S
authors: Honda
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Hideo
authors: H
authors: Machimura
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Kiyokazu
authors: K
authors: Matoba
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Fuyuki
authors: F
authors: Minagawa
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Nobuaki
authors: N
authors: Minami
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Yukiko
authors: Y
authors: Miyairi
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Atsuko
authors: A
authors: Mokubo
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Tetsuya
authors: T
authors: Motomiya
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Manabu
authors: M
authors: Waseda
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Masaaki
authors: M
authors: Miyakawa
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan.
authors: Yoshikazu
authors: Y
authors: Naka
authors: Department of Endocrinology and Metabolism, Yokohama City University, Kanagawa, Japan.
authors: Yasuo
authors: Y
authors: Terauchi
authors: Department of Internal Medicine, Division of Metabolism and Endocrinology, St. Marianna University School of Medicine, Kanagawa, Japan.
authors: Yasushi
authors: Y
authors: Tanaka
authors: The Study Group of the Diabetes Committee, Kanagawa Physicians Association, Kanagawa, Japan. Electronic address: ikuro@matsuba-web.com.
authors: Ikuro
authors: I
authors: Matsuba
mesh_terms: D000328:Adult; D044466:Asian People; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011719:Pyrazines / Q000627:therapeutic use*; D012189:Retrospective Studies; D000068900:Sitagliptin Phosphate; D014230:Triazoles / Q000627:therapeutic use*
chemical_list: D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin; D011719:Pyrazines; D000068900:Sitagliptin Phosphate; D014230:Triazoles
keywords: Glycemic control; Insulin; Sitagliptin; Type 2 diabetes