title: The relationship between complete blood count parameters and Fontaine's Stages in patients with peripheral arterial disease.
abstract: OBJECTIVE
  The aim of the present study is to evaluate whether blood count parameters differ according to the stages of Fontaine's classification and to investigate the relationship between hemogram parameters and the severity of the disease.
  
  
  METHODS
  Eighty-two peripheral arterial disease patients were examined prospectively. Patients were classified according to the Fontaine classification system. Fifty newly diagnosed patients were included in the study. The neutrophil-to-lymphocyte ratio, mean platelet volume, and red blood cell distribution width values were recorded.
  
  
  RESULTS
  Mean neutrophil-to-lymphocyte ratio values were found to be 3.31 ± 1.1% in Stage I, 3.11 ± 1.3% in Stage II, and 3.48 ± 1.1% in Stage III (p > 0.05). Mean platelet volume values were found to be 7.8 ± 0.6 fl (Stage I), 8.2 ± 1.0 fl (Stage II), and 9.0 ± 0.9 fl (Stage III) (p < 0.05). Red blood cell distribution width values were found to be 13.6 ± 1.0% in Stage I, 14.8 ± 1.7% in Stage II, and 15.4 ± 2.3% in Stage III, being significantly different among all three stages (p < 0.05).
  
  
  CONCLUSIONS
  Both red blood cell distribution width and mean platelet volume are found to be associated with the severity of atherosclerotic disease in patients with peripheral arterial disease. This finding hypothesizes that complete blood counting parameters may serve as a beneficial and cost-effective method for monitoring atherosclerotic peripheral disease.
authors: Department of Cardiovascular Surgery, Medical School of Dicle University, Diyarbakir, Turkey.
authors: Sinan
authors: S
authors: Demirtas
authors: Department of Cardiovascular Surgery, Medical School of Dicle University, Diyarbakir, Turkey oguzk2002@gmail.com.
authors: Oguz
authors: O
authors: Karahan
authors: Department of Cardiovascular Surgery, Medical School of Dicle University, Diyarbakir, Turkey.
authors: Suleyman
authors: S
authors: Yazici
authors: Department of Cardiovascular Surgery, Medical School of Dicle University, Diyarbakir, Turkey.
authors: Orkut
authors: O
authors: Guclu
authors: Department of Cardiovascular Surgery, Medical School of Dicle University, Diyarbakir, Turkey.
authors: Ahmet
authors: A
authors: Caliskan
authors: Department of Cardiovascular Surgery, Medical School of Dicle University, Diyarbakir, Turkey.
authors: Celal
authors: C
authors: Yavuz
authors: Cardiovascular Surgery Clinic, Ataturk Education and Research Hospital, Ankara, Turkey.
authors: Aslihan
authors: A
authors: Kucuker
authors: Department of Cardiovascular Surgery, Medical School of Dicle University, Diyarbakir, Turkey.
authors: Binali
authors: B
authors: Mavitas
mesh_terms: D000328:Adult; D000368:Aged; D001772:Blood Cell Count; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000097:blood* / Q000145:classification* / Q000175:diagnosis / Q000601:surgery
keywords: Complete blood counting parameters; mean platelet volume; neutrophil-to-lymphocyte ratio; peripheral arterial disease; red blood cell distribution width