title: [Correlation of clinical outcome and spinopelvic sagittal alignment after surgical posterior intervertebral fusion combined with pedicle screw fixation for Low-grade isthmic lumbar spondylolisthesis].
abstract: OBJECTIVE
  To investigate the effect of the sagittal alignment of the spine and pelvis after surgical posterior intervertebral fusion combined with pedicle screw fixation for low-grade isthmic lumbar spondylolisthesis, and to assess the effectiveness.
  
  
  METHODS
  Between October 2009 and October 2011, 30 patients with low-grade isthmic spondylolisthesis underwent surgical posterior intervertebral fusion combined with pedicle screw fixation, and the clinical data were retrospectively reviewed. There were 14 males and 16 females with an average age of 56.7 years (range, 48-67 years). The pre- and post-operative radiographic parameters, such as percentage of slipping (PS), intervertebral space height, angle of slip (AS), thoracic kyphosis (TK), thoracolumbar junction angle (TLJ), sagittal vertical axis (SVA), lumbar lordosis (LL), spino-sacral angle (SSA), sacral slope (SS), pelvic tilt (PT), and pelvic incidence (PI) were measured. The functional evaluation was made using the Oswestry Disability Index (ODI). Pearson correlation were used to investigate the association between all parameters and ODI score.
  
  
  RESULTS
  PS, intervertebral space height, AS, and ODI were improved significantly compared withproperative ones (P < 0.05). Significant differences were found in the other parameters between pre- and post-operation (P < 0.05) except TLJ and TK. The alteration of SVA showed significant correlation with the changes of PS, PI, PT, LL, SS, AS, SSA, and ODI. The alteration of SSA showed significant correlation with the changes of PS, PI, LL, SS, AS, PT, and ODI.
  
  
  CONCLUSIONS
  Surgical posterior intervertebral fusion combined with pedicle screw fixation for low-grade isthmic spondylolisthesis can effectively improve and maintain the spinal sagittal parameters. SVA and SSA are adequate to evaluate pre-and post-operative balance. The good clinical outcome is closely related with the improved of SVA and SSA.
authors: Department of Orthopaedics, Dongying People's Hospital, Dongying Shandong, 257091, P.R.China. jiawei20100303@163.com
authors: Liang
authors: L
authors: Li
authors: Department of Orthopaedics, Dongying People's Hospital, Dongying Shandong, 257091, P.R.China.
authors: Haitao
authors: H
authors: Sui
authors: Department of Orthopaedics, Dongying People's Hospital, Dongying Shandong, 257091, P.R.China.
authors: Xuezhong
authors: X
authors: Yu
authors: Department of Orthopaedics, Dongying People's Hospital, Dongying Shandong, 257091, P.R.China.
authors: Baoen
authors: B
authors: Jiang
mesh_terms: D000368:Aged; D001863:Bone Screws; D016025:Bone Transplantation; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010388:Pelvis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D004856:Postural Balance; D012189:Retrospective Studies; D013123:Spinal Fusion / Q000295:instrumentation / Q000379:methods*; D013131:Spine / Q000000981:diagnostic imaging* / Q000503:physiopathology; D013168:Spondylolisthesis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome