title: Effect of a short-term exercise program on glycemic control measured by fructosamine test in type 2 diabetes patients.
abstract: BACKGROUND
  Glycated hemoglobin (A1C) and Fasting Plasma Glucose (FPG) are the two monitoring blood glucose tests most frequently used. However, both methods are shown to be insensitive to detect glycemic variations in short duration periods. Therefore, we aimed to assess the effect of a short-term exercise program on glycemic levels measured by fructosamine concentrations in type 2 diabetes patients.
  
  
  METHODS
  Eight volunteers (51.1 ± 8.2 years) underwent a supervised exercise program during eight weeks (3 d.wk-1, 50-60% of VO2 peak for 30-60 minutes). The body composition, VO2 peak, A1C, FPG, fructosamine and capillary blood glucose (CBG) were evaluated. We used ANOVA - One Way for repeated measures followed by Tukey post-hoc test and paired t test. P values <0.05 were considered significant.
  
  
  RESULTS
  We found statistical differences on the concentrations of fructosamine, VO2 peak and CBG. However, A1C and FPG showed no statistical difference. Fructosamine declined by 15% (57 μmol/L) between the beginning and the end of the study. Individually, 50% of the sample reached the reference values for the normality in fructosamine test. VO2 peak increased by 14.8% (3.8 ml.kg-1.min-1) and CBG decreased on an average of 34.4% (69.3 mg/dL).
  
  
  CONCLUSIONS
  Fructosamine test is effective in the evaluation of glucose with type 2 diabetes patients when undergoing a short exercise program, alternatively to the traditional A1C and FPG assessment. Our results are relevant in clinical practice, because the significant improvement in glycemic status can help to evaluate the inclusion of exercise as adjunct therapy to replace the prescription of additional drugs in poorly controlled patients.
authors: Bruno P
authors: BP
authors: Moura
authors: Department of Physical Education, Human Performance Laboratory, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil. pramorim@ufv.br.
authors: Paulo Rs
authors: PR
authors: Amorim
authors: Bruno Pp
authors: BP
authors: Silva
authors: Sylvia Cc
authors: SC
authors: Franceschini
authors: Janice S
authors: JS
authors: Reis
authors: João Cb
authors: JC
authors: Marins