title: The roles of occipitotemporal cortex in reading, spelling, and naming.
abstract: We evaluated the hypothesis that Brodmann's area (BA) 37 within left occipitotemporal cortex has at least two important functions in lexical processing. One role is the computation of case-, font-, location-, and orientation-independent grapheme descriptions for written word recognition and production (reading and spelling). This role may depend on the medial part of BA 37, in left midfusiform gyrus. The second role is in accessing modality-independent lexical representations for output, for naming and for reading and spelling of irregular or exception words. This role may depend on the lateral part of BA 37 in inferior temporal cortex. We tested these hypotheses in 234 participants with acute left hemisphere ischaemic stroke who underwent magnetic resonance imaging (MRI) and language testing within 48 hours of onset of stroke symptoms.
authors: a Department of Neurology , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
authors: Rajani
authors: R
authors: Sebastian
authors: Yessenia
authors: Y
authors: Gomez
authors: Richard
authors: R
authors: Leigh
authors: Cameron
authors: C
authors: Davis
authors: Melissa
authors: M
authors: Newhart
authors: Argye E
authors: AE
authors: Hillis
mesh_terms: D000328:Adult; D000368:Aged; D020520:Brain Infarction / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D001931:Brain Mapping / Q000379:methods; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology*; D003072:Cognition Disorders / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009778:Occipital Lobe / Q000473:pathology / Q000503:physiopathology*; D010364:Pattern Recognition, Visual / Q000502:physiology; D011932:Reading; D012660:Semantics; D014956:Writing
keywords: Acute ischaemic stroke; Aphasia; Lesion studies; Naming; Reading; Spelling