title: Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma.
abstract: Macrophages are critical proponents of the growth and development of pancreatic ductal adenocarcinoma. However, if properly instructed, macrophages can acquire anti-tumor properties, including the capacity to degrade the fibrous matrix that surrounds neoplastic lesions and to eliminate malignant cells, eventually leading to tumor regression.
authors: Abramson Cancer Center; Department of Medicine; Division of Hematology-Oncology; University of Pennsylvania Perelman School of Medicine; Philadelphia, PA USA.
authors: Gregory L
authors: GL
authors: Beatty
keywords: PET imaging; cancer; fibrosis; macrophage; metabolism; pancreas; tumoricidal