title: Current progress of aptamer-based molecular imaging.
abstract: Aptamers, single-stranded oligonucleotides, are an important class of molecular targeting ligand. Since their discovery, aptamers have been rapidly translated into clinical practice. They have been approved as therapeutics and molecular diagnostics. Aptamers also possess several properties that make them uniquely suited to molecular imaging. This review aims to provide an overview of aptamers' advantages as targeting ligands and their application in molecular imaging.
authors: Department of Radiation Oncology, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina.
authors: Andrew Z
authors: AZ
authors: Wang
authors: Omid C
authors: OC
authors: Farokhzad
mesh_terms: D052157:Aptamers, Nucleotide / Q000378:metabolism; D006801:Humans; D008024:Ligands; D057054:Molecular Imaging / Q000379:methods*; D015335:Molecular Probes / Q000378:metabolism
chemical_list: D052157:Aptamers, Nucleotide; D008024:Ligands; D015335:Molecular Probes
keywords: aptamer; aptamers; molecular diagnostics; molecular imaging probes