title: Evaluation of bacterial cellulose/hyaluronan nanocomposite biomaterials.
abstract: Bacterial cellulose (BC) is useful in the biomedical field because of its unique structure and properties. The high nano-porosity of BC allows other materials to be incorporated and form reinforced composites. Here we describe the preparation and characterization of novel BC/hyaluronan (HA) nanocomposites with a 3-D network structure. BC/HA was obtained using a solution impregnation method. Elemental and ATR-FTIR analyses showed that this method is highly effective to form composites with BC. Weight loss analysis showed that BC/HA have a lower water loss than BC at 37 °C. The total surface area and pore volume of BC/HA films gradually decreased with the HA content, as followed by FE-SEM analysis. The elongation at break of BC/HA films gradually increased as the HA content increased. Thermogravimetric analysis showed that the weight loss for the BC/HA composites were lower than for pure BC between 250 and 350 °C. The results of weight loss, elongation at break and thermal stability suggested that these novel BC/HA films could be applied potentially as wound dressing materials.
authors: Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, PR China; National Engineering Research Center for Nano-Medicine, Huazhong University of Science and Technology, Wuhan 430074, PR China.
authors: Ying
authors: Y
authors: Li
authors: Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, PR China.
authors: Shuang
authors: S
authors: Qing
authors: Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, PR China; National Engineering Research Center for Nano-Medicine, Huazhong University of Science and Technology, Wuhan 430074, PR China.
authors: Jianhai
authors: J
authors: Zhou
authors: Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, PR China; National Engineering Research Center for Nano-Medicine, Huazhong University of Science and Technology, Wuhan 430074, PR China. Electronic address: yang_sunny@yahoo.com.
authors: Guang
authors: G
authors: Yang
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D002482:Cellulose / Q000096:biosynthesis / Q000737:chemistry*; D041822:Gluconacetobacter xylinus / Q000737:chemistry* / Q000378:metabolism; D006820:Hyaluronic Acid / Q000737:chemistry*; D053761:Nanocomposites / Q000737:chemistry*; D013696:Temperature
chemical_list: D001672:Biocompatible Materials; D002482:Cellulose; D006820:Hyaluronic Acid
keywords: Bacterial cellulose; Hyaluronan; Nanocomposites; Wound dressing