title: Francisella tularensis intracellular survival: to eat or to die.
abstract: Francisella tularensis is a highly infectious facultative intracellular bacterium causing the zoonotic disease tularemia. Numerous attributes required for F. tularensis intracellular multiplication have been identified recently. However, the mechanisms by which the majority of them interfere with the infected host are still poorly understood. The following review summarizes our current knowledge on the different steps of Francisella intramacrophagic life cycle and expands on the importance of nutrient acquisition.
authors: Université Paris Descartes, Sorbonne Paris Cité, Bâtiment Leriche, 96 rue Didot, 75993 Paris Cedex 14, France; INSERM, U1002, UnitÈ de PathogÈnie des Infections SystÈmiques, Paris, France.
authors: Monique
authors: M
authors: Barel
authors: Université Paris Descartes, Sorbonne Paris Cité, Bâtiment Leriche, 96 rue Didot, 75993 Paris Cedex 14, France; INSERM, U1002, UnitÈ de PathogÈnie des Infections SystÈmiques, Paris, France. Electronic address: alain.charbit@inserm.fr.
authors: Alain
authors: A
authors: Charbit
keywords: Francisella tularensis; Intracellular parasitism; Nutritional immunity