title: [Research progress in comparison of minimally invasive versus open transforaminal lumbar interbody fusion].
abstract: OBJECTIVE
  To review the latest comparative research of minimally invasive transforaminal lumbar interbody fusion (TLIF) and traditional open approach.
  
  
  METHODS
  The domestic and foreign literature concerning the comparative research of minimally invasive TLIF and traditional open TLIF was reviewed, then intraoperative indicators, length of hospitalization, effectiveness, complication, fusion rate, and the effect on paraspinal muscles were analyzed respectively.
  
  
  RESULTS
  Minimally invasive TLIF has less blood loss and shorter length of hospitalization, but with longer operation and fluoroscopic time. Minimally invasive surgery has the same high fusion rate as open surgery, however, its effectiveness is not superior to open surgery, and complication rate is relatively higher. In the aspect of the effect on paraspinal muscles, in creatine kinase, multifidus cross-sectional area, and atrophy grading, minimally invasive surgery has no significant reduced damage on paraspinal muscles.
  
  
  CONCLUSIONS
  Minimally invasive TLIF is not significantly superior to open TLIF, and it does not reduce the paraspinal muscles injury. But prospective double-blind randomized control trials are still needed for further study.
authors: Department of Orthopaedics, the 3rd Affiliated Hospital of Southern Medical University & Academy of Orthopaedics of Guangdong Province, Guangzhou Guangdong, 510630, P.R. China.
authors: Kai
authors: K
authors: Su
authors: Department of Orthopaedics, the 3rd Affiliated Hospital of Southern Medical University & Academy of Orthopaedics of Guangdong Province, Guangzhou Guangdong, 510630, P.R. China.
authors: Ying
authors: Y
authors: Guo
authors: Department of Orthopaedics, the 3rd Affiliated Hospital of Southern Medical University & Academy of Orthopaedics of Guangdong Province, Guangzhou Guangdong, 510630, P.R. China.
authors: Zhongmin
authors: Z
authors: Zhang
authors: Department of Orthopaedics, the 3rd Affiliated Hospital of Southern Medical University & Academy of Orthopaedics of Guangdong Province, Guangzhou Guangdong, 510630, P.R. China.
authors: Dadi
authors: D
authors: Jin
mesh_terms: D016063:Blood Loss, Surgical; D006801:Humans; D007902:Length of Stay; D017116:Low Back Pain / Q000209:etiology / Q000601:surgery; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D019060:Minimally Invasive Surgical Procedures / Q000009:adverse effects; D010147:Pain Measurement; D064170:Paraspinal Muscles / Q000293:injuries; D011183:Postoperative Complications / Q000453:epidemiology*; D011859:Radiography; D013123:Spinal Fusion / Q000379:methods*; D016896:Treatment Outcome