title: [Hypoxic preconditioning modifies the activity of pro- and antioxidant systems in rat hippocampus].
abstract: The effects of repetitive mild hypobaric hypoxic preconditioning upon pro- and antioxidant systems in rat hippocampus were studied. It was found that three-trial preconditioning by mild hypobaric hypoxia (360 mm Hg, 2 h) induced moderate oxidative stress immediately after the last preconditioning trial. In addition, it down-regualted the levels of peptide antioxidants (Trx-1, Trx-2, Cu,Zn-SOD) and several lipid peroxidation products 24 h later.
authors: M S
authors: MS
authors: Kislin
authors: S A
authors: SA
authors: Stroev
authors: T S
authors: TS
authors: Glushchenko
authors: E I
authors: EI
authors: Tiul'kova
authors: M
authors: M
authors: Pelto-Huikko
authors: M O
authors: MO
authors: Samoĭlov
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D002462:Cell Membrane / Q000201:enzymology / Q000378:metabolism; D006624:Hippocampus / Q000201:enzymology / Q000378:metabolism*; D000860:Hypoxia / Q000201:enzymology / Q000378:metabolism* / Q000503:physiopathology; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D009474:Neurons / Q000201:enzymology / Q000378:metabolism; D018384:Oxidative Stress / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D013482:Superoxide Dismutase / Q000096:biosynthesis; D013879:Thioredoxins / Q000096:biosynthesis
chemical_list: D000975:Antioxidants; D008054:Lipid Peroxides; C495697:Txn1 protein, rat; C516113:Txn2 protein, rat; D013879:Thioredoxins; D013482:Superoxide Dismutase