title: Tea consumption and prostate cancer: an updated meta-analysis.
abstract: OBJECTIVE
  Tea is supposed to have chemopreventive effect against various cancers. However, the protective role of tea in prostate cancer is still controversial. The aim of this study is to elucidate the association between tea consumption and prostate cancer risk by meta-analysis.
  
  
  METHODS
  A total of 21 published articles were retrieved via both computerized searches and review of references. Estimates of OR/RR for highest versus non/lowest tea consumption levels were pooled on the basis of random effect model or fixed effect model as appropriate. Stratified analyses on tea type, population and study design were also conducted.
  
  
  RESULTS
  No statistical significance was detected between tea consumption and prostate cancer risk in meta-analysis of all included studies (odds ratio (OR) = 0.86, 95% CI (0.69-1.04)). Furthermore, stratified analyses on population (Asian, OR = 0.81, 95% CI (0.55-1.08); non-Asian, OR = 0.89, 95% CI (0.72-1.07)) and tea type (green tea, OR = 0.79, 95% CI (0.43-1.14); black tea, OR = 0.88, 95% CI (0.73-1.02)) also yielded non-significant association. Only the case-control study subgroup demonstrated a borderline protective effect for tea consumption against prostate cancer (OR = 0.77, 95% CI (0.55-0.98)).
  
  
  CONCLUSIONS
  Our analyses did not support the conclusion that tea consumption could reduce prostate cancer risk. Further epidemiology studies are needed.
authors: Yi-wei
authors: YW
authors: Lin
authors: Zheng-hui
authors: ZH
authors: Hu
authors: Xiao
authors: X
authors: Wang
authors: Qi-qi
authors: QQ
authors: Mao
authors: Jie
authors: J
authors: Qin
authors: Xiang-yi
authors: XY
authors: Zheng
authors: Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road 79, Hangzhou 310003, Zhejiang Province, China. xielp@zjuem.zju.edu.cn.
authors: Li-ping
authors: LP
authors: Xie
mesh_terms: D006801:Humans; D008297:Male; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000209:etiology / Q000517:prevention & control*; D012307:Risk Factors; D013662:Tea
chemical_list: D013662:Tea