title: Angiografic and pressoric changes determined by splenectomy with left gastric vein ligature in mansoni schistosomiasis.
abstract: BACKGROUND
  In hepatosplenic schistosomiasis occurs diffuse hepatic fibrosis associated with venous congestion of the portal system resulting in hepatosplenomegaly. It can produce digestive hemorrhage caused by rupture of esophageal and stomach varices or peptic gastroduodenal mucosal lesions.
  
  
  OBJECTIVE
  To study the effects of splenectomy and ligature of the left gastric vein on portohepatic hemodynamics.
  
  
  METHODS
  Twenty-three patients with hepatosplenic schistosomiasis mansoni were studied before and about two weeks after operation through angiographic diameter of the common and proper hepatic artery, splenic artery, superior mesenteric artery, portal vein, superior mesenteric vein and left gastric vein. The pressures of the inferior vena cava and central venous pressure, free hepatic vein, the hepatic sinusoidal and occluded vein were measured.
  
  
  RESULTS
  The splenectomy and ligature of the left gastric vein determined low morbidity and null mortality. It determined significant addition to the following variables: diameters of the common and proper hepatic artery; diameter of the superior mesenteric vein. It determined non significant increase on the following measurements: right atrial pressure and diameter of the superior mesenteric artery. It determined non significant decrease to the following variables: inferior vena cava pressure; free hepatic vein pressure; occluded hepatic vein pressure; sinusoidal pressure, diameter of the portal vein.
  
  
  CONCLUSIONS
  Splenectomy and ligature of the left gastric vein do not determine portal hemodynamic changes capable of breaking the functional hemodinamic balance that characterizes the hepatosplenic mansoni schistosomiasis.
authors: Fernanda Maria Fernández
authors: FM
authors: Pereira
authors: João
authors: J
authors: Evangelista-Neto
authors: Norma
authors: N
authors: Brito
authors: Fernando
authors: F
authors: Amaral
authors: Olival Cirilo Lucena
authors: OC
authors: da Fonseca-Neto
authors: Cláudio Moura
authors: CM
authors: Lacerda
mesh_terms: D000328:Adult; D000368:Aged; D000792:Angiography; D001794:Blood Pressure; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008026:Ligation; D008107:Liver Diseases / Q000469:parasitology / Q000503:physiopathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D057234:Preoperative Period; D012555:Schistosomiasis mansoni / Q000503:physiopathology* / Q000601:surgery*; D013156:Splenectomy; D013158:Splenic Diseases / Q000469:parasitology* / Q000503:physiopathology* / Q000601:surgery; D014680:Veins / Q000601:surgery; D055815:Young Adult