title: Chronic gastritis in China: a national multi-center survey.
abstract: BACKGROUND
  Chronic gastritis is one of the most common findings at upper endoscopy in the general population, and chronic atrophic gastritis is epidemiologically associated with the occurrence of gastric cancer. However, the current status of diagnosis and treatment of chronic gastritis in China is unclear.
  
  
  METHODS
  A multi-center national study was performed; all patients who underwent diagnostic upper endoscopy for evaluation of gastrointestinal symptoms from 33 centers were enrolled. Data including sex, age, symptoms and endoscopic findings were prospectively recorded.
  
  
  RESULTS
  Totally 8892 patients were included. At endoscopy, 4389, 3760 and 1573 patients were diagnosed to have superficial gastritis, erosive gastritis, and atrophic gastritis, respectively. After pathologic examination, it is found that atrophic gastritis, intestinal metaplasia and dysplasia were prevalent, which accounted for 25.8%, 23.6% and 7.3% of this patient population. Endoscopic features were useful for predicting pathologic atrophy (PLR = 4.78), but it was not useful for predicting erosive gastritis. Mucosal-protective agents and PPI were most commonly used medications for chronic gastritis.
  
  
  CONCLUSIONS
  The present study suggests non-atrophic gastritis is the most common endoscopic finding in Chinese patients with upper GI symptoms. Precancerous lesions, including atrophy, intestinal metaplasia and dysplasia are prevalent in Chinese patients with chronic gastritis, and endoscopic features are useful for predicting pathologic atrophy.
authors: Yiqi
authors: Y
authors: Du
authors: Yu
authors: Y
authors: Bai
authors: Pei
authors: P
authors: Xie
authors: Jingyuan
authors: J
authors: Fang
authors: Xiaozhong
authors: X
authors: Wang
authors: Xiaohua
authors: X
authors: Hou
authors: Dean
authors: D
authors: Tian
authors: Chengdang
authors: C
authors: Wang
authors: Yandi
authors: Y
authors: Liu
authors: Weihong
authors: W
authors: Sha
authors: Bangmao
authors: B
authors: Wang
authors: Yanqing
authors: Y
authors: Li
authors: Guoliang
authors: G
authors: Zhang
authors: Yan
authors: Y
authors: Li
authors: Ruihua
authors: R
authors: Shi
authors: Jianming
authors: J
authors: Xu
authors: Youming
authors: Y
authors: Li
authors: Minghe
authors: M
authors: Huang
authors: Shengxi
authors: S
authors: Han
authors: Jie
authors: J
authors: Liu
authors: Xu
authors: X
authors: Ren
authors: Pengyan
authors: P
authors: Xie
authors: Zhangliu
authors: Z
authors: Wang
authors: Lihong
authors: L
authors: Cui
authors: Jianqiu
authors: J
authors: Sheng
authors: Hesheng
authors: H
authors: Luo
authors: Zhaohui
authors: Z
authors: Wang
authors: Xiaoyan
authors: X
authors: Zhao
authors: Ning
authors: N
authors: Dai
authors: Yuqiang
authors: Y
authors: Nie
authors: Yiyou
authors: Y
authors: Zou
authors: Bing
authors: B
authors: Xia
authors: Zhining
authors: Z
authors: Fan
authors: Zhitan
authors: Z
authors: Chen
authors: Sanren
authors: S
authors: Lin
authors: Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China. li.zhaoshen@hotmail.com.
authors: Zhao-Shen
authors: ZS
authors: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D002908:Chronic Disease; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005756:Gastritis / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology*; D005757:Gastritis, Atrophic / Q000453:epidemiology / Q000473:pathology; D006801:Humans; D008297:Male; D008679:Metaplasia / Q000453:epidemiology / Q000473:pathology; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D013270:Stomach / Q000473:pathology*; D055815:Young Adult
chemical_list: D054328:Proton Pump Inhibitors