title: [Takayasu's arteritis in pregnancy--a case report].
abstract: We present a case report of pregnant woman with Takayasu's arteritis diagnosed in childhood. The treatment was modified owing to the fact that the patient wished to get pregnant and she conceived spontaneously within the first year after that. Vasculitis activity was low during pregnancy Hypertension was treated with methyldopa and metoprolol. After the confirmation of pregnancy daily administration of prednizone and enoxaparin (at a dose of 5 mg and 40 mg, respectively) has been started. In the third trimester of pregnancy the values of blood pressure increased. The patient required higher doses of antihypertensive drugs. Proteinuria appeared in the daily urine collection. The values of liver enzymes have increased. Elective cesarean section was performed at 37 weeks of gestation due to narrow oscillations revealed by CTG and weaker fetal movements reported by the mother A male infant (weight 2840 g, Apgar 10) was born. The mother and the child were discharged on day 5 of the postpartum. Treatment with steroids, antihypertensive drugs, thyroxine and enoxaparin was continued. Hypertension and preeclampsia are the most dangerous complications in pregnant women with Takayasu's disease. They can affect the health status of the mother and the child. Maternal blood pressure should be controlled very accurately on the two superior limbs. Vaginal delivery of the baby is preferred. Cesarean section is indicated when the values of the maternal blood pressure are elevated in the second part of vaginal delivery
authors: Katedra i Klinika Połoznictwa i Perinatologii Uniwersytetu Medycznego w Lublinie, Polska. dorotak@mp.pl
authors: Dorota
authors: D
authors: Darmochwał-Kolarz
authors: Katedra i Klinika Połoznictwa i Perinatologii Uniwersytetu Medycznego w Lublinie, Polska.
authors: Anita
authors: A
authors: Chara
authors: Katedra i Klinika Połoznictwa i Perinatologii Uniwersytetu Medycznego w Lublinie, Polska.
authors: Michał
authors: M
authors: Korzeniewski
authors: Katedra i Klinika Połoznictwa i Perinatologii Uniwersytetu Medycznego w Lublinie, Polska.
authors: Bozena
authors: B
authors: Leszczyńska-Gorzelak
authors: Katedra i Klinika Połoznictwa i Perinatologii Uniwersytetu Medycznego w Lublinie, Polska.
authors: Jan
authors: J
authors: Oleszczuk
mesh_terms: D000959:Antihypertensive Agents / Q000008:administration & dosage*; D002585:Cesarean Section; D017984:Enoxaparin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011256:Pregnancy Outcome; D011859:Radiography; D013625:Takayasu Arteritis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D013974:Thyroxine / Q000008:administration & dosage
chemical_list: D000959:Antihypertensive Agents; D017984:Enoxaparin; D013974:Thyroxine