title: [Mutual role of factors of endotoxicosis and intra-abdominal hypertension syndrome in pathogenesis of abdominal sepsis].
abstract: The mutual role of the main factors of endotoxicosis and intraabdominal hypertension syndrome (IHS) were studied in pathogenesis of abdominal sepsis, basing on analysis of the treatment results in 156 patients, suffering this disease. The contents of neutrophils, macrophages, interleukins (IL-6, IL-10) were studied in peritoneal exudate as the indices of the source of inflammation in abdominal cavity. There was established the mutual strengthening of the endotoxicosis and IHS factors, what causes the clinical signs of the organ dysfunction, determines the course severity and outcome of pathological process in the organism. Such approach to pathogenesis of abdominal sepsis permits in time and adequately to elaborate the certain program of treatment in the patients.
authors: N A
authors: NA
authors: Veliev
authors: D N
authors: DN
authors: Gasanova
authors: V F
authors: VF
authors: Ismailov
mesh_terms: D000005:Abdomen / Q000503:physiopathology*; D001772:Blood Cell Count; D019446:Endotoxemia / Q000097:blood / Q000150:complications / Q000503:physiopathology; D006098:Granulocytes / Q000473:pathology; D006801:Humans; D016753:Interleukin-10 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D059325:Intra-Abdominal Hypertension / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D008264:Macrophages / Q000473:pathology; D012307:Risk Factors; D018805:Sepsis / Q000097:blood* / Q000150:complications* / Q000503:physiopathology; D012720:Severity of Illness Index
chemical_list: C508609:IL10 protein, human; C508600:IL6 protein, human; D015850:Interleukin-6; D016753:Interleukin-10