title: Hypothalamic tanycytes: gatekeepers to metabolic control.
abstract: How circulating signals of hunger and satiety enter the brain to reach neurons that govern energy balance has long remained a matter of controversy and speculation. Balland et al. (2014) now elucidate molecular mechanisms by which a highly specialized hypothalamic glial cell regulates transport of leptin across the blood-brain barrier.
authors: Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg & Division of Metabolic Diseases, Technische Universität München, Munich, Germany.
authors: Yuanqing
authors: Y
authors: Gao
authors: Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg & Division of Metabolic Diseases, Technische Universität München, Munich, Germany. Electronic address: matthias.tschoep@helmholtz-muenchen.de.
authors: Matthias H
authors: MH
authors: Tschöp
authors: Univ Paris Diderot, Sorbonne Paris Cité, Unité de Biologie Fonctionnelle et Adaptative (BFA) UMR 8251 CNRS, F-75205, Paris, France.
authors: Serge
authors: S
authors: Luquet
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D063928:Ependymoglial Cells / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism*; D020738:Leptin / Q000378:metabolism*; D008297:Male
chemical_list: D020738:Leptin