title: Resecting without detecting the lesion in extratemporal lobe epilepsy?
abstract: Nonlesional extratemporal lobe epilepsy (ETLE) often persists following resection of the site of ictal onset, localized with definitive intracranial EEG recordings.(1,2) In lesional ETLE, however, lesionectomy with resection of a single electrophysiologically defined ictal onset (ictogenic) zone often stops seizures immediately and permanently.(1,2) In temporal lobe epilepsy (TLE), a single ictogenic site can be resected, either with an accompanying lesion or in the absence of an MRI-detected lesion, and is a highly efficacious epilepsy therapy.(2) Efforts to increase surgical efficacy in nonlesional ETLE have focused on localization by functional imaging to substitute for lesion localization by structural imaging.
authors: From the University of Minnesota Medical School, Minneapolis.
authors: Thomas R
authors: TR
authors: Henry
mesh_terms: D004827:Epilepsy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D015899:Tomography, Emission-Computed, Single-Photon