title: Arterial spin-labeling magnetic resonance imaging for diagnosis of late seizure after stroke.
abstract: OBJECTIVE
  Arterial spin labeling (ASL) is a non-invasive modality of magnetic resonance imaging (MRI) used to evaluate cerebral perfusion without a contrast agent. The usefulness of ASL for diagnosis in the acute phase of late seizure after stroke was evaluated.
  
  
  METHODS
  Twelve consecutive patients diagnosed with late seizure after stroke were enrolled in this study. MRI including ASL was performed for each patient at the time of the emergency department visit. Eight of the patients underwent electroencephalography (EEG).
  
  
  RESULTS
  All patients showed hyperperfusion around the stroke lesion on ASL. Only 6 patients showed high signal intensity along the cerebral cortex around the stroke lesion on diffusion-weighted imaging. The patients who underwent EEG showed slow activity, but paroxysmal discharges such as spikes or sharp waves were not observed.
  
  
  CONCLUSIONS
  ASL was able to reveal hyperperfusion and was of great diagnostic value in the peri-ictal phase of late seizure after stroke.
authors: Department of Neurology and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Yosuke
authors: Y
authors: Miyaji
authors: Department of Neurology and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Mutsumi
authors: M
authors: Yokoyama
authors: Department of Neurology and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Yuichi
authors: Y
authors: Kawabata
authors: Department of Neurology and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Hideto
authors: H
authors: Joki
authors: Department of Neurosurgery and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Yuji
authors: Y
authors: Kushi
authors: Department of Neurosurgery and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Yasutaka
authors: Y
authors: Yokoi
authors: Department of Neurosurgery and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Jo
authors: J
authors: Sasame
authors: Department of Neurosurgery and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Shunsuke
authors: S
authors: Seki
authors: Department of Neurosurgery and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Kentaro
authors: K
authors: Mori
authors: Department of Neurosurgery and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Tomoya
authors: T
authors: Kamide
authors: Department of Neurosurgery and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Akira
authors: A
authors: Tamase
authors: Department of Neurosurgery and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Hiroshi
authors: H
authors: Shima
authors: Department of Neurosurgery and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Motohiro
authors: M
authors: Nomura
authors: Department of Neurosurgery and Stroke Medicine, Yokohama Sakae Kyosai Hospital, Japan.
authors: Yoshihisa
authors: Y
authors: Kitamura
authors: Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan. Electronic address: ftanaka@yokohama-cu.ac.jp.
authors: Fumiaki
authors: F
authors: Tanaka
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D004569:Electroencephalography / Q000379:methods; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D012640:Seizures / Q000175:diagnosis* / Q000209:etiology* / Q000378:metabolism; D013113:Spin Labels; D020521:Stroke / Q000150:complications* / Q000175:diagnosis* / Q000378:metabolism
chemical_list: D013113:Spin Labels
keywords: Arterial spin labeling; Diffusion-weighted imaging; Hyperperfusion; Late seizure; Magnetic resonance imaging; Post-stroke epilepsy; Post-stroke seizure