title: [Anti-GQ1b syndrome: report of four cases].
abstract: Anti-GQ1b syndrome includes Miller Fisher Syndrome (MFS), Guillain Barré Syndrome (GBS), Bicker staff`s brain stem encephalitis (BBE) and Acute Ophtamoplegia (AO). We report four patients aged 16 to 76 years, with anti-GQ1b syndrome. All presented with MFS, one of them evolved to GBS pharyngeal-cervical-brachial variant and other to GBS with BBE. All had a previous history of diarrhea or upper respiratory tract infection. All had positive anti-GQ1b serum antibodies. Both brain magnetic resonance imaging and cerebrospinal fluid analysis were normal. Electrophysiology studies were compatible with a demyelinating disease. Two patients needed airway protection with an orotracheal tube and developed dysautonomia. All four patients were treated with immunomodulation. On the sixth month follow-up, patients had only minimal alterations in the neurological examination.
authors: Reinaldo
authors: R
authors: Uribe S M
authors: Felipe
authors: F
authors: Suárez H
authors: Patricio
authors: P
authors: Sandoval R
authors: Patricio
authors: P
authors: Mellado T
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000888:Antibodies, Anti-Idiotypic / Q000097:blood*; D001933:Brain Stem; D004660:Encephalitis / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D005732:Gangliosides / Q000097:blood* / Q000276:immunology; D020275:Guillain-Barre Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019846:Miller Fisher Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D009886:Ophthalmoplegia / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000888:Antibodies, Anti-Idiotypic; D005732:Gangliosides; D016756:Immunoglobulins, Intravenous; C039129:GQ1b ganglioside