title: Cervical cytopathological findings in Korean women with Chlamydia trachomatis, Mycoplasma hominis, and Ureaplasma urealyticum infections.
abstract: This is to investigate the cervical cytological abnormalities associated with Chlamydia trachomatis, Mycoplasma hominis, Mycoplasma genitalium, and Ureaplasma urealyticum infections on routine screen. A total of 714 subjects who had undergone cervical Pap smears and concomitant analyses for cervical infections were included by a retrospective search. The frequencies of reactive cellular change (RCC) and squamous epithelial abnormalities were significantly higher in Chlamydia positive subjects than in uninfected subjects (P<0.001). Of the 124 subjects tested for M. hominis, M. genitalium, and U. urealyticum, 14 (11%) were positive for M. hominis and 29 (23%) were positive for U. urealyticum. Squamous abnormalities were more frequent in subjects with Ureaplasma infections than in uninfected subjects (24% versus 8%). Taking together these findings, C. trachomatis and U. urealyticum may have a causal role in the development of cervical epithelial changes, including RCC. Thus, extra awareness is warranted in cervical screening of women with Chlamydia or Ureaplasma infections.
authors: Laboratory of Reproductive Endocrinology, Department of Anatomy & Cell Biology, College of Medicine, Hanyang University, San 17 Haengdang-dong, Seongdong-gu, Seoul 133-792, Republic of Korea.
authors: Yuri
authors: Y
authors: Choi
authors: Laboratory of Reproductive Endocrinology, Department of Anatomy & Cell Biology, College of Medicine, Hanyang University, San 17 Haengdang-dong, Seongdong-gu, Seoul 133-792, Republic of Korea.
authors: Jaesook
authors: J
authors: Roh
mesh_terms: D000328:Adult; D002584:Cervix Uteri / Q000382:microbiology* / Q000473:pathology*; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000453:epidemiology; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008875:Middle Aged; D009175:Mycoplasma Infections / Q000175:diagnosis* / Q000453:epidemiology; D019535:Mycoplasma hominis / Q000302:isolation & purification; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D016869:Ureaplasma Infections / Q000175:diagnosis* / Q000453:epidemiology; D016990:Ureaplasma urealyticum / Q000302:isolation & purification; D055815:Young Adult