title: Adiponectin and leptin molecular actions and clinical significance in breast cancer.
abstract: Obesity is an important public health problem and major risk factor for postmenopausal breast cancer. Adipose tissue is the major component involved in the control of the metabolism through energy homeostasis, adipocyte differentiation, insulin sensitivity and the activation of anti-inflammatory metabolic and immune pathways. Leptin and Adiponectin pathways are involved in proliferation process in breast cancer. Current review describes potential relationship between the molecular actions and clinical significance of leptin and adiponectin in breast cancer.
authors: Research Scholar, Bhagwan Mahavir Medical Research Center, Department of Genetics, Mahavir Marg, A.C.Guards, Hyderabad-500004, Andhra Pradesh, India.
authors: Mohan Reddy
authors: MR
authors: Nalabolu
authors: Research Scholar, Bhagwan Mahavir Medical Research Center, Department of Genetics, Mahavir Marg, A.C.Guards, Hyderabad-500004, Andhra Pradesh, India.
authors: Kalyani
authors: K
authors: Palasamudram
authors: Research Scholar, Bhagwan Mahavir Medical Research Center, Department of Genetics, Mahavir Marg, A.C.Guards, Hyderabad-500004, Andhra Pradesh, India.
authors: Kaiser
authors: K
authors: Jamil
keywords: Adiponectin; Breast Cancer; Cytokine; Leptin; Obesity