title: Percutaneous computer tomography-guided ethanol sympathicolysis for the treatment of resistant arterial hypertension.
abstract: OBJECTIVE
  As an alternative to catheter-based radiofrequency (RF) ablation, renal sympathicolysis can also be achieved by image-guided percutaneous injection of ethanol around the renal artery.
  
  
  METHODS
  We report the case of a 50-year-old man with refractory hypertension and end-stage renal failure of unclear etiology who was treated with computed tomography-guided percutaneous periarterial ethanol sympathicolysis.
  
  
  RESULTS
  The procedure was painless. The patient's BP decreased within 6 days from a baseline value of 172/84 mm Hg (1 week before treatment) to a sustained decreased value of 143/70 mm Hg 1 month after intervention, i.e., a decrease by 29/14 mm Hg. The patient's hypertension-related headache resolved.
  
  
  CONCLUSIONS
  Image-guided periarterial ethanol injection for renal sympathetic denervation in a patient with drug-resistant hypertension is feasible. We provide a detailed description of this new interventional procedure and discuss its potential advantages compared with catheter-based RF ablation.
authors: Department of Radiology, Charité, Humboldt University Medical School, Augustenburger Platz 1, 13353, Berlin, Germany, florian.streitparth@charite.de.
authors: F
authors: F
authors: Streitparth
authors: B
authors: B
authors: Gebauer
authors: P
authors: P
authors: Nickel
authors: P
authors: P
authors: Reinke
authors: P
authors: P
authors: Freyhardt
authors: G
authors: G
authors: Wieners
authors: B
authors: B
authors: Hamm
authors: R W
authors: RW
authors: Günther
mesh_terms: D003287:Contrast Media; D000431:Ethanol / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D021621:Imaging, Three-Dimensional; D007676:Kidney Failure, Chronic / Q000150:complications / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional; D012077:Renal Artery / Q000000981:diagnostic imaging*; D012720:Severity of Illness Index; D013563:Sympathectomy, Chemical / Q000379:methods*; D013565:Sympatholytics / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media; D013565:Sympatholytics; D000431:Ethanol