title: [Oxidative stress in the of alcoholic liver disease].
abstract: Parameters reflecting oxidative stress (OS) have been studied in 37 patients with alcoholic liver disease (ALD) during admission to the hospital and 2 weeks after the beginning of therapy. The patients were divided into 3 groups: alcoholic hepatitis (AH), alcoholic cirrhosis with hepatic insufficiency (the group C with Child-Paquet) and terminal stage patients (they subsequently died). All patients were characterized by a significant increase in plasma products of lipid peroxidation (conjugated diene and malondialdehyde) and decrease of the ceruloplasmin level. The coefficient K OS significantly exceeded normal values both on admission and after the 2-week course of traditional treatment. This suggests an important role of the OS with ALD.
authors: L F
authors: LF
authors: Panchenko
authors: B V
authors: BV
authors: Davydov
authors: N N
authors: NN
authors: Terebilina
authors: V Iu
authors: VIu
authors: Baronets
authors: A S
authors: AS
authors: Zhuravleva
mesh_terms: D000328:Adult; D002570:Ceruloplasmin / Q000378:metabolism*; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation; D008108:Liver Diseases, Alcoholic / Q000097:blood*; D008297:Male; D008315:Malondialdehyde / Q000097:blood*; D008875:Middle Aged; D018384:Oxidative Stress
chemical_list: D008315:Malondialdehyde; D002570:Ceruloplasmin