title: Selective anion sensing by chiral macrocyclic receptors with multiple hydrogen-bonding sites.
abstract: Chiral macrocycles featuring sulfonamide and/or amide groups as anion-binding sites were synthesized. X-ray crystal structures and DFT calculations have shown that they adopt different conformations that may lead to unique binding behavior. Indeed, various anions could be sensed by their colorimetric and/or fluorescence signal output. The chiral macrocycles showed chiral recognition for chiral anions. Furthermore, a multisensor array with two or four chiral receptors discriminated seven phosphate anions (AMP, ADP, ATP, CMP, GMP, Pi, and PPi) with 100% classification accuracy.
authors: Division of Chemistry and Biotechnology, Graduate School of Natural Science and Technology, Okayama University , Tsushima, Okayama 700-8530, Japan.
authors: Tadashi
authors: T
authors: Ema
authors: Keiichi
authors: K
authors: Okuda
authors: Sagiri
authors: S
authors: Watanabe
authors: Takayuki
authors: T
authors: Yamasaki
authors: Tsuyoshi
authors: T
authors: Minami
authors: Nina A
authors: NA
authors: Esipenko
authors: Pavel
authors: P
authors: Anzenbacher
mesh_terms: D000577:Amides / Q000737:chemistry; D000838:Anions / Q000737:chemistry; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D047028:Macrocyclic Compounds / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D010710:Phosphates / Q000737:chemistry
chemical_list: D000577:Amides; D000838:Anions; D047028:Macrocyclic Compounds; D010710:Phosphates