title: Colorectal cancer screening: the northern trust experience.
abstract: OBJECTIVE
  Colorectal cancer (CRC) is the third most common type of cancer with resulting major mortality. In a bid to reduce the mortality, bowel cancer screening has been established in the United Kingdom. The screening programme was commenced in Northern Ireland in 2010 within the Northern Health and Social Care Trust, following its implementation in England and Scotland. This study aimed to look at early outcome data for bowel cancer screening in Northern Ireland and compare data with other regions in the UK.
  
  
  METHODS
  A retrospective analysis was conducted of patients who tested faecal occult blood (FOB) positive and attended for pre-assessment between May 2010 and May 2011. Data was also collected from the computerised endoscopy database (Endoscribe®). Patient demographics, colonoscopic depth of insertion, findings and complications were documented. Subsequent surgical management, pathological staging and final outcome were also noted.
  
  
  RESULTS
  182 patients attended for pre-assessment in the time frame and 178 patients proceeded to colonoscopy. The commonest pathology encountered was polyps, identified in 95 (52.7%) patients. Macroscopically 13 cancers were seen on endoscopy and a further two were found on post-operative histology of polyps that were not amenable to endoscopic resection. In addition, 5 malignant polyps were found on histological analysis of the excised polyps. The staging of cancers was favourable with 35% being Dukes' A stage.
  
  
  CONCLUSIONS
  Outcomes from the first year of colorectal cancer screening in the Northern Trust are in keeping with early results from previous studies in terms of cancer detection rates per colonoscopy and proportion of early stage cancers. However, the adenoma detection rate was higher than anticipated.
authors: Departments of.
authors: David
authors: D
authors: Neely
authors: Departments of.
authors: William
authors: W
authors: Campbell
authors: Departments of.
authors: Philip
authors: P
authors: Davey
authors: Surgery and Gastroenterology, Northern Trust, Antrim Area Hospital, Bush Road, BT41 2RL, N. Ireland.
authors: Colin
authors: C
authors: Rodgers
authors: Departments of.
authors: David
authors: D
authors: McCrory
mesh_terms: D003111:Colonic Polyps / Q000473:pathology* / Q000601:surgery; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000517:prevention & control*; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D009780:Occult Blood; D012189:Retrospective Studies
keywords: FOB; colonoscopy; colorectal cancer; screening; sigmoidoscopy