title: Computer-supported indirect-form lifestyle-modification support program using Lifestyle Intervention Support Software for Diabetes Prevention (LISS-DP) for people with a family history of type 2 diabetes in a medical checkup setting: a randomized controlled trial.
abstract: OBJECTIVE
  To investigate the effect of a computer-supported indirect-form lifestyle-modification program using Lifestyle Intervention Support Software for Diabetes Prevention (LISS-DP), as a clinically feasible strategy for primary prevention, on diet and physical activity habits in adults with a family history of type 2 diabetes.
  
  
  METHODS
  This was a two-arm, randomized controlled trial: (1) lifestyle intervention (LI) group (n=70); (2) control (n=71). Healthy adults aged 30-60 years with a history of type 2 diabetes among their first-degree relatives were recruited. LI group received three times of lifestyle intervention using LISS-DP during six-month intervention period via mail.
  
  
  RESULTS
  Lifestyle intervention group showed significantly greater decrease in energy intake six months after baseline, compared to control (-118.31 and -24.79 kcal/day, respectively, p=0.0099, Cohen's d=0.22), though the difference disappeared 1 year after from baseline. No difference was found in physical activity energy expenditure.
  
  
  CONCLUSIONS
  A computer-based, non-face-to-face lifestyle intervention was effective on dietary habits, only during the intervention period. Further examination of the long-term effects of such intervention and physical activity is required.
authors: Department of Adult Nursing, School of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. Electronic address: ynakawatase-tky@umin.ac.jp.
authors: Yuri
authors: Y
authors: Tokunaga-Nakawatase
authors: Department of Adult Nursing, School of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
authors: Masakazu
authors: M
authors: Nishigaki
authors: Department of Nursing, Graduate School of Health Sciences, Kobe University, Kobe, Hyogo, Japan.
authors: Chiemi
authors: C
authors: Taru
authors: Department of Nursing, Graduate School of Health Sciences, Kobe University, Kobe, Hyogo, Japan.
authors: Ikuko
authors: I
authors: Miyawaki
authors: Social Insurance Chuo General Hospital, Shinjuku-ku, Tokyo, Japan.
authors: Junko
authors: J
authors: Nishida
authors: Department of Adult Nursing, School of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
authors: Shiho
authors: S
authors: Kosaka
authors: Department of Gerontological Nursing/Wound Care Management, Division of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
authors: Hiromi
authors: H
authors: Sanada
authors: Department of Adult Nursing, School of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
authors: Keiko
authors: K
authors: Kazuma
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000235:genetics / Q000517:prevention & control*; D004032:Diet / Q000009:adverse effects; D002149:Energy Intake; D004734:Energy Metabolism; D005247:Feeding Behavior; D005260:Female; D020022:Genetic Predisposition to Disease; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D010174:Pamphlets; D010353:Patient Education as Topic / Q000379:methods*; D010375:Pedigree; D012307:Risk Factors; D040242:Risk Reduction Behavior; D012984:Software; D013813:Therapy, Computer-Assisted; D013997:Time Factors; D016896:Treatment Outcome
keywords: Computer-supported; Family history of type 2 diabetes; Indirect-form; Lifestyle intervention; Primary prevention