title: Transmissibility of novel H7N9 and H9N2 avian influenza viruses between chickens and ferrets.
abstract: Previous studies have shown that the H7N9 avian influenza virus cannot be transmitted efficiently between ferrets via respiratory droplets. Here, we studied the infectivity of the H7N9 avian influenza virus in chickens and its transmissibility from infected to naïve chickens and ferrets. The H7N9 virus (A/Anhui/1/2013) replicated poorly in chickens and could not be transmitted efficiently from infected chickens to naïve chickens and ferrets. H7N9 virus was shed from chicken tracheae for only 2 days after infection and from chicken cloacae for only 1 day after infection, while the H9N2 avian influenza virus, which is endemic in chickens in many Asian countries, was shed from tracheae and cloacae for 8 days after infection. Taken together, our results suggest that chickens may be a poor agent of transmission for the H7N9 virus to other chickens and to mammals, including humans.
authors: Laboratory of Influenza Research, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea; Institute for Influenza Virus, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea.
authors: Keun Bon
authors: KB
authors: Ku
authors: Laboratory of Influenza Research, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea; Institute for Influenza Virus, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea.
authors: Eun Hye
authors: EH
authors: Park
authors: Laboratory of Influenza Research, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea; Institute for Influenza Virus, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea.
authors: Jung
authors: J
authors: Yum
authors: Laboratory of Influenza Research, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea; Institute for Influenza Virus, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea.
authors: Heui Man
authors: HM
authors: Kim
authors: Laboratory of Influenza Research, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea; Institute for Influenza Virus, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea.
authors: Young Myong
authors: YM
authors: Kang
authors: Laboratory of Influenza Research, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea; Institute for Influenza Virus, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea.
authors: Jeong Cheol
authors: JC
authors: Kim
authors: Laboratory of Influenza Research, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea; Institute for Influenza Virus, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea.
authors: Ji An
authors: JA
authors: Kim
authors: Laboratory of Public Health, Chungnam National University, College of Veterinary Medicine, Daejeon 305-764, Republic of Korea.
authors: Hyun Soo
authors: HS
authors: Kim
authors: Laboratory of Influenza Research, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea; Institute for Influenza Virus, Chungnam National University, College of Veterinary Medicine, 220 Gung Dong, Daejeon 305-764, Republic of Korea. Electronic address: seos@cnu.ac.kr.
authors: Sang Heui
authors: SH
authors: Seo
mesh_terms: D000818:Animals; D002645:Chickens; D004195:Disease Models, Animal; D005289:Ferrets; D006801:Humans; D064766:Influenza A Virus, H7N9 Subtype / Q000502:physiology*; D053127:Influenza A Virus, H9N2 Subtype / Q000502:physiology*; D005585:Influenza in Birds / Q000635:transmission* / Q000821:virology; D007251:Influenza, Human / Q000635:transmission* / Q000821:virology; D009976:Orthomyxoviridae Infections / Q000635:transmission / Q000662:veterinary* / Q000821:virology; D011201:Poultry Diseases / Q000635:transmission* / Q000821:virology; D017201:Virus Shedding
keywords: Chickens; H7N9; H9N2; Influenza virus; Transmission