title: Therapy of acute hypertension in hospitalized children and adolescents.
abstract: Acute hypertension (HTN) in hospitalized children and adolescents occurs relatively frequently, and in some cases, if not recognized and treated promptly, it can lead to hypertensive crisis with potentially significant morbidity and mortality. In contrast to adults, where acute HTN is most likely due to uncontrolled primary HTN, children and adolescents with acute HTN are more likely to have secondary HTN. This review will briefly cover evaluation of acute HTN and various age-specific etiologies of secondary HTN and provide more in-depth discussion on treatment targets, potential risks of acute HTN therapy, and available pediatric data on intravenous and oral antihypertensive agents, and it proposes treatment schema including unique therapy of specific secondary HTN scenarios.
authors: Pediatric Nephrology, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA, 15206, USA, tennille.webb@chp.edu.
authors: Tennille N
authors: TN
authors: Webb
authors: Ibrahim F
authors: IF
authors: Shatat
authors: Yosuke
authors: Y
authors: Miyashita
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000367:Age Factors; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002673:Child, Hospitalized; D000075222:Essential Hypertension; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D012306:Risk
chemical_list: D000959:Antihypertensive Agents