title: Concise enantiospecific total synthesis of tubingensin A.
abstract: We report the enantiospecific total synthesis of (+)-tubingensin A. Our synthesis features an aryne cyclization to efficiently introduce the vicinal quaternary stereocenters of the natural product and proceeds in only nine steps (longest linear sequence) from known compounds.
authors: Department of Chemistry and Biochemistry, University of California , Los Angeles, California 90095, United States.
authors: Adam E
authors: AE
authors: Goetz
authors: Amanda L
authors: AL
authors: Silberstein
authors: Michael A
authors: MA
authors: Corsello
authors: Neil K
authors: NK
authors: Garg
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D002227:Carbazoles / Q000737:chemistry*; D003500:Cyclization; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D002227:Carbazoles