title: Examining cerebral angiogenesis in response to physical exercise.
abstract: Capillary growth and expansion (angiogenesis) is a prerequisite for many forms of neural and behavioral plasticity. It is commonly observed in both brain and muscle of aerobically exercising animals. As such, several histological methods have been used to quantify capillary density, including perfusion with India ink, various Nissl stains, and immunohistochemistry. In this chapter, we will describe these histological procedures and describe the stereological analysis used to quantify vessel growth in response to aerobic exercise.
authors: Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
authors: Kiersten L
authors: KL
authors: Berggren
authors: Jacob J M
authors: JJ
authors: Kay
authors: Rodney A
authors: RA
authors: Swain
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000098:blood supply* / Q000502:physiology; D002560:Cerebrovascular Circulation; D007150:Immunohistochemistry; D018919:Neovascularization, Physiologic; D010805:Physical Conditioning, Animal; D051381:Rats; D013194:Staining and Labeling; D016707:Tissue Fixation