title: [Nutritional status of the persons living with HIV/AIDS; its relationship with T CD4+ cells counts].
abstract: BACKGROUND
  Malnutrition might be present in people living with HIV/aids (PHIV/aids), and be associated with derangement of the immune system.
  
  
  OBJECTIVE
  To assess the association between the nutricional status of the PHIV/aids and the counts of T CD4+ cells.
  
  
  METHODS
  Observational, analytical and cross-sectional.
  
  
  METHODS
  The nutricional status of 217 PHIV/aids in the Pinar del Río province, Cuba (Men: 72.4%; Age at the moment of HIV/aids diagnosis: < 30 years: 62.2%; CD4+ Counts < 350 cells x mm(-3): 32.3%; Anti-retroviral therapy: 33.2%) was indistinctively established by means of the Body Mass Index (BMI), the Global Subjective Assessment (SGA) and the Chang's algorithm. The association between the nutritional status and the CD4+ counts was estimated from the corresponding odds-ratios (OR), indistinctively calculated from the cross-products ratios of a 2 x 2 contingency table; or the coefficients of the logistic regression model.
  
  
  RESULTS
  Malnutrition frequency was dependent from the nutritional assessment method: BMI: 3.7%; Chang's algorithm: 8.8%; SGA: 10.6%; respectively. Nutritional status was weakly associated with CD4+ counts: BMI: ORContingencyTable = 3.69 (p > 0.05); Chang's algorithm: ORContingencyTable = 2.55 (p = 0.047); and SGA: ORContingencyTable = 1.72 (p > 0.05); respectively. When the study serie was adjusted according anti-retroviral therapy (ARVT), association between CD4+ and nutritional status was as follows: BMI: ORLogisticRegression = 0.367 (p = 0.083); Chang's Algorithm: ORLogisticRegression = 2.604 (p = 0.050); and SGA: ORLogisticRegression = 1.714 (p = 0.232); respectively.
  
  
  CONCLUSIONS
  Inception of ARVT modifies the association that might exist between the immune system and nutritional status. Reduction of CD4+ counts in a PHIV/aids was weakly associated with derangement of nutritional indicators. It is likely that body weight excess might be modifying this association: 29.0% of the studied PHIV/aids had BMI values >= 25.0 Kg x m(-2).
authors: Universidad de Ciencias Médicas de Pinar del Río. Pinar del Río. Cuba.. ssergito@infomed.sld.cu.
authors: Elisa Maritza
authors: EM
authors: Linares Guerra
authors: Universidad de Ciencias Médicas de Pinar del Río. Pinar del Río. Cuba.. ssergito@infomed.sld.cu.
authors: Sergio
authors: S
authors: Santana Porbén
authors: Universidad de Ciencias Médicas de Pinar del Río. Pinar del Río. Cuba..
authors: Olimpia
authors: O
authors: Carrillo Fornés
authors: Universidad de Ciencias Médicas de Pinar del Río. Pinar del Río. Cuba..
authors: Maria Amparo
authors: MA
authors: León Sánchez
authors: Universidad de Ciencias Médicas de Pinar del Río. Pinar del Río. Cuba..
authors: José Guillermo
authors: JG
authors: Sanabria Negrín
authors: Universidad de Ciencias Médicas de Pinar del Río. Pinar del Río. Cuba..
authors: Nadia
authors: N
authors: Acosta Núñez
authors: Universidad de Ciencias Médicas de Pinar del Río. Pinar del Río. Cuba..
authors: Alina
authors: A
authors: Pla Cruz
authors: Universidad de Ciencias Médicas de Pinar del Río. Pinar del Río. Cuba..
authors: Emilia
authors: E
authors: Coniell Linares
mesh_terms: D000328:Adult; D018791:CD4 Lymphocyte Count; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000097:blood* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009752:Nutritional Status