title: Graphene-based materials functionalized with elastin-like polypeptides.
abstract: Graphene-based materials commonly require functionalization for biological applications in order to control their physical/colloidal properties and to introduce additional capabilities, such as stimuli-responsiveness and affinity to specific biomolecules. Here, we functionalized CVD-grown graphene and graphene oxide with a genetically engineered elastin-like polypeptide fused to a graphene binding peptide and then showed that the resulting hybrid materials exhibit thermo- and photoresponsive behaviors. Furthermore, we demonstrate that our genetic engineering strategy allows for the facile introduction of bioactivity to reduced graphene oxide. The stimuli-responsiveness and genetic tunability of our graphene-protein nanocomposites are attractive for addressing future biomedical applications.
authors: Department of Bioengineering, University of California, Berkeley , Berkeley, California 94720, United States.
authors: Eddie
authors: E
authors: Wang
authors: Malav S
authors: MS
authors: Desai
authors: Kwang
authors: K
authors: Heo
authors: Seung-Wuk
authors: SW
authors: Lee
mesh_terms: D004549:Elastin / Q000737:chemistry* / Q000235:genetics; D006108:Graphite / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry* / Q000235:genetics; D015202:Protein Engineering / Q000379:methods; D013499:Surface Properties
chemical_list: D010455:Peptides; D006108:Graphite; D004549:Elastin