title: Orthogonal resonators for pulse in vivo electron paramagnetic imaging at 250 MHz.
abstract: A 250 MHz bimodal resonator with a 19 mm internal diameter for in vivo pulse electron paramagnetic resonance (EPR) imaging is presented. Two separate coaxial cylindrical resonators inserted one into another were used for excitation and detection. The Alderman-Grant excitation resonator (AGR) showed the highest efficiency among all the excitation resonators tested. The magnetic field of AGR is confined to the volume of the detection resonator, which results in highly efficient use of the radio frequency power. A slotted inner single loop single gap resonator (SLSG LGR), coaxial to the AGR, was used for signal detection. The resulting bimodal resonator (AG/LGR) has two mutually orthogonal magnetic field modes; one of them has the magnetic field in the axial direction. The resonator built in our laboratory achieved 40 dB isolation over 20 MHz bandwidth with quality factors of detection and excitation resonators of 36 and 11 respectively. Considerable improvement of the B1 homogeneity and EPR image quality in comparison with reflection loop-gap resonator of similar size and volume was observed.
authors: Center for EPR Imaging In Vivo Physiology, Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA.
authors: Subramanian V
authors: SV
authors: Sundramoorthy
authors: Center for EPR Imaging In Vivo Physiology, Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA. Electronic address: bepel@uchicago.edu.
authors: Boris
authors: B
authors: Epel
authors: Center for EPR Imaging In Vivo Physiology, Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA. Electronic address: h-halpern@uchicago.edu.
authors: Howard J
authors: HJ
authors: Halpern
mesh_terms: D000818:Animals; D003952:Diagnostic Imaging / Q000379:methods*; D004574:Electromagnetic Fields; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods*; D004581:Electronics; D005260:Female; D006614:Hindlimb / Q000033:anatomy & histology / Q000473:pathology; D007091:Image Processing, Computer-Assisted; D051379:Mice; D008809:Mice, Inbred C3H; D009374:Neoplasms, Experimental / Q000473:pathology; D019047:Phantoms, Imaging
keywords: EPR; EPR imaging; In vivo; Resonator