title: Does an aerobic endurance programme have an influence on information processing in migraineurs?
abstract: BACKGROUND
  Migraine is a disorder of central information processing which is characterized by a reduced habituation of event-related potentials. There might be positive effects of aerobic exercise on brain function and pain. The aim of this study was to investigate the influence of exercise on information processing and clinical course of migraine.
  
  
  METHODS
  33 patients completed a ten-week aerobic exercise programme. To examine the influence of the treatment on information processing and attention, Trail Making Test (TMT) A and B, d2-Letter Cancellation Test (LCT) and recordings of the Contingent Negative Variation (CNV) were performed before and after the training.
  
  
  RESULTS
  Patients showed a significant reduction of the migraine attack frequency, the iCNV-amplitude and the processing time for TMT-A and TMT-B after treatment. Moreover, there was a significant increase of the habituation and positive changes in parameters of attention (d2-LCT) after the training.
  
  
  CONCLUSIONS
  This study demonstrates that aerobic exercise programme influences central information processing and leads to clinical effects on the migraine symptomatology. The results can be interpreted in terms of an improvement of a dysfunctional information processing and a stimulus selection under aerobic exercise.
authors: Institute of Medical Psychology, University Clinic of Schleswig-Holstein, Campus Kiel, Diesterwegstraße 10 - 12, 24113 Kiel, Germany. claudiah.overath@googlemail.com.
authors: Claudia H
authors: CH
authors: Overath
authors: Stephanie
authors: S
authors: Darabaneanu
authors: Marie C
authors: MC
authors: Evers
authors: Wolf-Dieter
authors: WD
authors: Gerber
authors: Melanie
authors: M
authors: Graf
authors: Armin
authors: A
authors: Keller
authors: Uwe
authors: U
authors: Niederberger
authors: Henrik
authors: H
authors: Schäl
authors: Michael
authors: M
authors: Siniatchkin
authors: Burkhard
authors: B
authors: Weisser
mesh_terms: D000328:Adult; D003265:Contingent Negative Variation / Q000502:physiology*; D004569:Electroencephalography / Q000379:methods; D005071:Evoked Potentials / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D005260:Female; D006185:Habituation, Psychophysiologic / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D010807:Physical Endurance / Q000502:physiology*