title: Long term survival analysis of hepatectomy for neuroendocrine tumour liver metastases.
abstract: BACKGROUND
  Liver is the commonest site for metastasis in patients with neuroendocrine tumour (NET). A vast majority of treatment strategies including liver directed nonsurgical therapy, liver directed surgical therapy, and nonliver directed therapy have been proposed. In this study we aim to investigate the outcome of liver resection in neuroendocrine tumour liver metastases (NELM).
  
  
  METHODS
  293 patients had hepatectomy for liver metastasis in our hospital between June 1996 and December 2010. Twelve patients were diagnosed to have NET in their final pathology and their data were reviewed.
  
  
  RESULTS
  The median ages of the patients were 48.5 years (range 20-71 years). Eight of the patients received major hepatectomy. Four patients received minor hepatectomy. The median operation time was 418 minutes (range 195-660 minutes). The median tumor size was 8.75 cm (range 0.9-21 cm). There was no hospital mortality. The overall one-year and three-year survivals were 91.7% and 55.6%. The one-year and three-year disease-free survivals were 33.3% and 16.7%.
  
  
  CONCLUSIONS
  Hepatectomy is an effective and safe treatment for NELM. Reasonable outcome on long term overall survival and disease-free survival can be achieved in this group of patients with a low morbidity rate.
authors: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.
authors: Tan To
authors: TT
authors: Cheung
authors: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.
authors: Kenneth S H
authors: KS
authors: Chok
authors: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.
authors: Albert C Y
authors: AC
authors: Chan
authors: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.
authors: Simon
authors: S
authors: Tsang
authors: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.
authors: Jeff W C
authors: JW
authors: Dai
authors: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.
authors: Brian H H
authors: BH
authors: Lang
authors: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.
authors: Thomas
authors: T
authors: Yau
authors: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.
authors: See Ching
authors: SC
authors: Chan
authors: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.
authors: Ronnie T P
authors: RT
authors: Poon
authors: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.
authors: Sheung Tat
authors: ST
authors: Fan
authors: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.
authors: Chung Mau
authors: CM
authors: Lo
mesh_terms: D000328:Adult; D000368:Aged; D015897:Comorbidity; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000401:mortality / Q000473:pathology*; D012307:Risk Factors; D016896:Treatment Outcome; D055815:Young Adult