title: [Progress on host range factors and their mechanisms of poxvirus].
abstract: Poxvirus is one of the most serious zoonosis pathogens, which has largest genome and broadest host spectrum. With the development of molecular biology, functional genomics, and immunology-related technology, the interactions between pathogen and the host, particularly a large array of host range factors and their functions have been increasingly discovered. These findings provide references for the molecular basis of poxvirus tissue tropism and host specificity. This review focus on the introduction of host range factors in major members of Chordopoxvirinae to highlight the understanding of the mechanisms of molecular genetic evolution, the host tropism, and cross-species infection of poxviruses.
authors: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Public Health of Agricultural Ministry, Lanzhou Veterinary Research Institute, CAAS, Lanzhou 730046, China. baig.love@163.com
authors: Gang
authors: G
authors: Bai
authors: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Public Health of Agricultural Ministry, Lanzhou Veterinary Research Institute, CAAS, Lanzhou 730046, China.
authors: Huai-Jie
authors: HJ
authors: Jia
authors: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Public Health of Agricultural Ministry, Lanzhou Veterinary Research Institute, CAAS, Lanzhou 730046, China.
authors: Xiao-Bing
authors: XB
authors: He
authors: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Public Health of Agricultural Ministry, Lanzhou Veterinary Research Institute, CAAS, Lanzhou 730046, China.
authors: Zhi-Zhong
authors: ZZ
authors: Jing
mesh_terms: D000818:Animals; D058507:Host Specificity; D054884:Host-Pathogen Interactions; D006801:Humans; D011212:Poxviridae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D011213:Poxviridae Infections / Q000662:veterinary* / Q000821:virology*; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism*
chemical_list: D014764:Viral Proteins