title: Purification of antibodies and antibody fragments using CaptureSelect™ affinity resins.
abstract: Ever since the introduction of bacterial derived surface proteins like protein A that demonstrate a natural binding reactivity towards antibodies, affinity chromatography has evolved into a well-established technology for the purification of antibodies and antibody fragments. Although high selectivity is provided by these types of affinity ligands, not all antibodies or antibody fragments are covered, which then forces the use of non-affinity-based processes that are less selective and often result in lower one-step purity and yield. To fill these gaps, we here describe a novel range of CaptureSelect(™) affinity resins that enables immunoaffinity chromatography for a much broader range of antibody targets.
authors: BAC BV, Life Technologies, Leiden, The Netherlands.
authors: Pim
authors: P
authors: Hermans
authors: Hendrik
authors: H
authors: Adams
authors: Frank
authors: F
authors: Detmers
mesh_terms: D000906:Antibodies / Q000302:isolation & purification*; D002846:Chromatography, Affinity; D007128:Immunoglobulin Fragments / Q000302:isolation & purification*
chemical_list: D000906:Antibodies; D007128:Immunoglobulin Fragments