title: Bacteriophage biosensors for antibiotic-resistant bacteria.
abstract: An increasing number of disease-causing bacteria are resistant to one or more anti-bacterial drugs utilized for therapy. Early and speedy detection of these pathogens is therefore very important. Traditional pathogen detection techniques, that include microbiological and biochemical assays are long and labor-intensive, while antibody or DNA-based methods require substantial sample preparation and purification. Biosensors based on bacteriophages have demonstrated remarkable potential to surmount these restrictions and to offer rapid, efficient and sensitive detection technique for antibiotic-resistant bacteria.
authors: Department of Anatomy, Physiology, and Pharmacology, Auburn AL 36849, USA.
authors: Irina
authors: I
authors: Sorokulova
authors: Eric
authors: E
authors: Olsen
authors: Vitaly
authors: V
authors: Vodyanoy
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D001435:Bacteriophages / Q000187:drug effects / Q000502:physiology*; D015374:Biosensing Techniques; D004352:Drug Resistance, Microbial / Q000187:drug effects*; D017930:Genes, Reporter
chemical_list: D000900:Anti-Bacterial Agents