title: Copper-catalyzed intermolecular trifluoromethylazidation of alkenes: convenient access to CF3 -containing alkyl azides.
abstract: A novel copper-catalyzed intermolecular trifluoromethylazidation of alkenes has been developed under mild reaction conditions. A variety of CF3 -containing organoazides were directly synthesized from a wide range of olefins, including activated and unactivated alkenes, and the resulting products can be easily transformed into the corresponding CF3 -containing amine derivatives.
authors: State Key Laboratory of Organometallic Chemistry, Shanghai, Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032 (China).
authors: Fei
authors: F
authors: Wang
authors: Xiaoxu
authors: X
authors: Qi
authors: Zhaoli
authors: Z
authors: Liang
authors: Pinhong
authors: P
authors: Chen
authors: Guosheng
authors: G
authors: Liu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001386:Azides / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006844:Hydrocarbons, Cyclic / Q000138:chemical synthesis / Q000737:chemistry; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D001386:Azides; D006844:Hydrocarbons, Cyclic; D006845:Hydrocarbons, Fluorinated; D003300:Copper
keywords: alkenes; azides; copper; fluorine; synthetic methods