title: Takotsubo cardiomyopathy: a review.
abstract: Takotsubo cardiomyopathy can occur after acute mental or physical stress, subarachnoid hemorrhage, ischemic stroke, major head trauma, acute medical illness or acute pheochromocytoma crisis. It is characterized by transient systolic dysfunction of the apical and/or midventricular segments in patients without epicardial coronary artery disease. The condition occurs most commonly in postmenopausal women, and is characterized by transient left ventricular dysfunction. The pathophysiology of the disorder remains to be elucidated but may involve catecholamine excess and vasospasm. Future studies, perhaps in the form of an international registry, may clarify the incidence, pathophysiology, clinical course, and prognosis of this disorder.
authors.affiliation: Division of Cardiovascular Disease, Department of Medicine, Stony Brook University Medical Center , Stony Brook, NY , USA.
authors.forename: Mahdi
authors.initials: M
authors.lastname: Veillet-Chowdhury
authors.forename: Syed Fahad
authors.initials: SF
authors.lastname: Hassan
authors.forename: Kathleen
authors.initials: K
authors.lastname: Stergiopoulos
mesh_terms: D003327:Coronary Disease / Q000503:physiopathology; D003329:Coronary Vasospasm / Q000503:physiopathology; D004837:Epinephrine / Q000502:physiology; D006801:Humans; D008833:Microcirculation; D009638:Norepinephrine / Q000502:physiology; D012008:Recurrence; D012307:Risk Factors; D012640:Seizures / Q000503:physiopathology; D012737:Sex Factors; D054549:Takotsubo Cardiomyopathy / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy
chemical_list: D009638:Norepinephrine; D004837:Epinephrine