title: Abnormal Lipid levels as a risk factor of eclampsia, study conducted in tertiary care Hospitals of Khyber Pakhtunkhwa Province - Pakistan.
abstract: OBJECTIVE
  To evaluate abnormal lipid metabolism as a risk factor of eclampsia in pregnant women.
  
  
  METHODS
  This cross sectional study was conducted in three tertiary care hospitals of Peshawar. Serum total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), very low density lipoprotein cholesterol (VLDL-C), triglyceride (TG), apolipoprotein A1 (APO-A1), APO-B100, lipoprotein-a (Lpa) were measured in 110 women with eclampsia and compared with 90 healthy pregnant women. Mean lipid levels in cases and controls were compared using student's t test".
  
  
  RESULTS
  Mean systolic/diastolic blood pressure, TC, TG, VLDL-C and Lpa levels were significantly higher (p<0.001) in patients compared to control women. Similarly TC: HDL-C, LDL-C: HDL-C and TG: HDL-C ratio in the patients group were significantly higher (p<0.001) and HDL-C: VLDL-C ratio was significantly lower (p<0.001) in the patients as compared to control group. Undesirable cholesterol were noted in 35.8% patients, HDL-C in 50.5%, borderline high concentration of LDL-C in 23.6%, high triglycerides levels in 73.2%, undesirable cholesterol ratio in 52.3% and undesirable LDL-C ratio were noted in 82.1% patients of eclampsia.
  
  
  CONCLUSIONS
  Serum lipids were found significantly higher thus early assessment may be helpful in prevention of complications in the eclampsia patients.
authors.affiliation: Rubina Nazli, MBBS, DGO, PhD, Institute of Basic Medical Sciences, Khyber Medical University, KPK Peshawar, Pakistan.
authors.forename: Rubina
authors.initials: R
authors.lastname: Nazli
authors.affiliation: Muhammad Akmal Khan, MBBS, FCPS, MRCP, Hayatabad Medical Complex, Peshawar, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Akmal Khan
authors.affiliation: Tasleem Akhtar, M.Phil, PhD, PMRC Research Centre Khyber Medical College Peshawar, Pakistan.
authors.forename: Tasleem
authors.initials: T
authors.lastname: Akhtar
authors.affiliation: Ghosia Lutfullah, M.Phil, PhD, Centre of Biotechnology & Microbiology, University of Peshawar, KPK Peshawar, Pakistan.
authors.forename: Ghosia
authors.initials: G
authors.lastname: Lutfullah
authors.affiliation: Nabila Sher Mohammad, MBBS, Khyber Girls Medical College, KPK Peshawar, Pakistan.
authors.forename: Nabila
authors.initials: N
authors.lastname: Sher Mohammad
authors.affiliation: Jawad Ahmad, MBBS, PhD, Institute of Basic Medical Sciences, Khyber Medical University, KPK Peshawar, Pakistan.
authors.forename: Jawad
authors.initials: J
authors.lastname: Ahmad
authors.affiliation: Jamila Haider, M.Phil scholar, Centre of Biotechnology & Microbiology, University of Peshawar, KPK Peshawar, Pakistan.
authors.forename: Jamila
authors.initials: J
authors.lastname: Haider
authors.affiliation: Hina Aslam, MBBS, Khyber Girls Medical College, KPK Peshawar, Pakistan.
authors.forename: Hina
authors.initials: H
authors.lastname: Aslam
keywords: Eclampsia; Hypertension; Khyber Pakhtunkhwa Province; Lipoprotein; Lipoprotein ratio