title: Cutaneous allergy to insulin: could statins and ACE inhibitors play a role? A case report.
abstract: Insulin allergy is rare. Both statins and angiotensin converting enzyme (ACE) inhibitors may cause local urticarial skin reactions and have been implicated to precipitate local reactions to insulin. We describe a case of a localised urticarial allergic reaction related to insulin use in a patient co-prescribed an ACE inhibitor and statin.
authors.affiliation: Department of Diabetes & Endocrinology, Morriston Hospital, ABM University NHS Trust, Swansea SA6 6NL, United Kingdom.
authors.forename: D
authors.initials: D
authors.lastname: Pitrola
authors.affiliation: Department of Diabetes & Endocrinology, Morriston Hospital, ABM University NHS Trust, Swansea SA6 6NL, United Kingdom.
authors.forename: C
authors.initials: C
authors.lastname: MacIver
authors.affiliation: Department of Diabetes & Endocrinology, Morriston Hospital, ABM University NHS Trust, Swansea SA6 6NL, United Kingdom; Diabetes Research Group, Swansea University, Singleton Park, Swansea SA2 8PP, United Kingdom.
authors.forename: A
authors.initials: A
authors.lastname: Mallipedhi
authors.affiliation: Department of Diabetes & Endocrinology, Morriston Hospital, ABM University NHS Trust, Swansea SA6 6NL, United Kingdom.
authors.forename: M
authors.initials: M
authors.lastname: Udiawar
authors.affiliation: Department of Diabetes & Endocrinology, Morriston Hospital, ABM University NHS Trust, Swansea SA6 6NL, United Kingdom.
authors.forename: D E
authors.initials: DE
authors.lastname: Price
authors.affiliation: Department of Diabetes & Endocrinology, Morriston Hospital, ABM University NHS Trust, Swansea SA6 6NL, United Kingdom; Diabetes Research Group, Swansea University, Singleton Park, Swansea SA2 8PP, United Kingdom. Electronic address: J.W.Stephens@Swansea.ac.uk.
authors.forename: J W
authors.initials: JW
authors.lastname: Stephens
mesh_terms: D000485:Allergens / Q000276:immunology; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D001323:Autoantibodies / Q000097:blood; D003093:Colitis, Ulcerative / Q000188:drug therapy; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D005500:Follow-Up Studies; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D007004:Hypoglycemic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D007328:Insulin / Q000009:adverse effects* / Q000276:immunology / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D014581:Urticaria / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000485:Allergens; D000806:Angiotensin-Converting Enzyme Inhibitors; D001323:Autoantibodies; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007004:Hypoglycemic Agents; D007328:Insulin
keywords: ACE inhibitor; Allergy; Insulin; Statin