title: Molecular biology of fuselloviruses and their satellites.
abstract: Fuselloviruses, also known as Sulfolobus Spindle-shaped viruses (SSVs), are "lemon"- or "spindle"-shaped double-stranded DNA viruses. Among them, SSV1, SSV2 and the satellite viruses pSSVx and pSSVi have been investigated at the structural, genetic, transcriptomic, proteomic and biochemical levels, thus becoming models for dissecting DNA replication/gene expression in Archaea. Important progress has been made including elucidation of temporal genome expression during virus infection and induction of replication, SSV1 lysogeny maintenance as well as differentially expression of pSSVx replicase. Future researches focusing on these model systems would yield insightful knowledge of life cycle and DNA replication of fuselloviruses.
authors.affiliation: Dipartimento di Biologia, Università degli Studi di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cinthia, Naples, Italy, contursi@unina.it.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Contursi
authors.forename: Salvatore
authors.initials: S
authors.lastname: Fusco
authors.forename: Raffaele
authors.initials: R
authors.lastname: Cannio
authors.forename: Qunxin
authors.initials: Q
authors.lastname: She
mesh_terms: D000595:Amino Acid Sequence; D001105:Archaea / Q000235:genetics / Q000378:metabolism / Q000821:virology*; D019241:Fuselloviridae / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity / Q000648:ultrastructure; D015967:Gene Expression Regulation, Viral; D008969:Molecular Sequence Data; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
chemical_list: D014764:Viral Proteins