title: Primary bone marrow Hodgkin lymphoma in an HIV-negative patient.
abstract: Classical Hodgkin lymphoma has distinct clinicopathological features and shows good response to treatment in most cases. Primary bone marrow-limited Hodgkin lymphoma is uncommon and primarily described in HIV-positive patients. It behaves as a distinct entity with aggressive clinical course and poor response to available treatments. We discuss here a case of Hodgkin lymphoma with isolated involvement of bone marrow in an HIV-negative patient, which was successfully treated with conventional chemotherapy.
authors.affiliation: Department of General Internal Medicine, University of Arkansas for Medical Sciences (UAMS), 4301W Markham St, Slot 634, Little Rock, AR, 72205, USA, brd.850@gmail.com.
authors.forename: Bhagirathbhai
authors.initials: B
authors.lastname: Dholaria
authors.forename: Daisy
authors.initials: D
authors.lastname: Alapat
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Arnaoutakis
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D019046:Bone Marrow Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D018023:HIV Seronegativity; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D049268:Positron-Emission Tomography; D016539:Reed-Sternberg Cells / Q000473:pathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome