title: Cystic fibrosis database (CFDB): a new web-based tool for cystic fibrosis specialists.
abstract: In order to help specialists involved in CF care and clinical research to know the current best evidence about clinical effectiveness of interventions in CF, we designed and developed a web-based, free access tool called "CFDB"--Cystic Fibrosis DataBase (www.inetflow.it/CFDB). The database was built by searching in Medline, Embase, Cochrane Library and worldwide trials registries all studies involving clinical interventions in CF. The tool lets the user define queries starting from one or more types of pathological conditions and one or more interventions. The output of the queries is structured in three levels: (1) how many and which studies deal with the conditions formulated in the query; (2) which are the main results of these studies; (3) a critical summary of the literature related to the query. This tool, providing a quick overview of the available evidence in clinical research in CF, may help clinical decision making, designing of new trials and building guidelines.
authors.affiliation: Italian CF Research Foundation, Verona, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Buzzetti
authors.forename: Natalia
authors.initials: N
authors.lastname: Cirilli
authors.forename: Laura
authors.initials: L
authors.lastname: Minicucci
authors.forename: Valeria
authors.initials: V
authors.lastname: Raia
authors.forename: Donatello
authors.initials: D
authors.lastname: Salvatore
authors.forename: Paolo
authors.initials: P
authors.lastname: Maffeis
mesh_terms: D003550:Cystic Fibrosis; D016208:Databases, Factual; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D013038:Specialization
keywords: clinical trials; cystic fibrosis; database; systematic reviews