title: Regional oxygen saturation index (rSO2) in brachioradialis and deltoid muscle. Correlation and prognosis in patients with respiratory sepsis.
abstract: OBJECTIVE
  To compare oxygen saturation index (rSO2) obtained simultaneously in two different brachial muscles.
  
  
  METHODS
  Prospective and observational study.
  
  
  METHODS
  Intensive care unit.
  
  
  METHODS
  Critically ill patients with community-acquired pneumonia.
  
  
  METHODS
  Two probes of NIRS device (INVOS 5100) were simultaneously placed on the brachioradialis (BR) and deltoid (D) muscles.
  
  
  METHODS
  rSO2 measurements were recorded at baseline (ICU admission) and at 24h. Demographic and clinical variables were registered. Pearson's correlation coefficient was used to assess the association between continuous variables. The consistency of the correlation was assessed using the intraclass correlation coefficient (ICC) and Bland-Altman plot. The predictive value of the rSO2 for mortality was calculated by ROC curve.
  
  
  RESULTS
  Nineteen patients were included with an ICU mortality of 21.1%. The rSO2 values at baseline and at 24h were significantly higher in D than in BR muscle. Values obtained simultaneously in both limbs showed a strong correlation and adequate consistency: BR (r=0.95; p<0.001; ICC=0.94; 95% CI: 0.90-0.96; p<0.001), D (r=0.88; p=0.01; ICC=0.88; 95% CI: 0.80-0.90; p>0.001) but a wide limit of agreement. Non-survivors had rSO2 values significantly lower than survivors at all times of the study. No patient with rSO2 >60% in BR died, and only 17.6% died with an rSO2 value >60% in D. Both muscles showed consistent discriminatory power for mortality.
  
  
  CONCLUSIONS
  Both BR and D muscles were appropriate for measuring rSO2.
authors.affiliation: Critical Care Department, Hospital Universitario de Tarragona Joan XXIII, Tarragona, Spain; Institut d'Investigació Sanitaria Pere Virgili, Universitat Rovira i Virgili, Tarragona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Bunyola, Mallorca, Spain. Electronic address: ahr1161@yahoo.es.
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez
authors.affiliation: Critical Care Department, Hospital Universitario de Tarragona Joan XXIII, Tarragona, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Claverias
authors.affiliation: Critical Care Department, Hospital Universitario de Tarragona Joan XXIII, Tarragona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Marín
authors.affiliation: Critical Care Department, Hospital Universitario de Tarragona Joan XXIII, Tarragona, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Magret
authors.affiliation: Critical Care Department, Hospital Universitario de Tarragona Joan XXIII, Tarragona, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Rosich
authors.affiliation: Critical Care Department, Hospital Universitario de Tarragona Joan XXIII, Tarragona, Spain; Institut d'Investigació Sanitaria Pere Virgili, Universitat Rovira i Virgili, Tarragona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Bunyola, Mallorca, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Bodí
authors.affiliation: Critical Care Department, Hospital Universitario de Tarragona Joan XXIII, Tarragona, Spain; Institut d'Investigació Sanitaria Pere Virgili, Universitat Rovira i Virgili, Tarragona, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Trefler
authors.affiliation: Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Bunyola, Mallorca, Spain; Department of CEXS, UPF, Servicio de Neumología, Hospital del Mar-IMIM, Barcelona, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Pascual
authors.affiliation: Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Bunyola, Mallorca, Spain; Department of CEXS, UPF, Servicio de Neumología, Hospital del Mar-IMIM, Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Gea
mesh_terms: D017714:Community-Acquired Infections / Q000378:metabolism; D057645:Deltoid Muscle / Q000378:metabolism*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism*; D011014:Pneumonia / Q000378:metabolism* / Q000401:mortality*; D011379:Prognosis; D011446:Prospective Studies; D018805:Sepsis / Q000378:metabolism* / Q000401:mortality*
chemical_list: D010100:Oxygen
keywords: Community-acquired pneumonia; Espectroscopia cercana al infrarrojo; Microcirculación; Microcirculation; Near-infrared; Neumonía comunitaria; Oxigenación tisular; Spectroscopy; Tissue oxygenation