title: Imaging features of fibrolamellar hepatocellular carcinoma.
abstract: OBJECTIVE
  Fibrolamellar hepatocellular carcinoma (HCC) is a rare primary liver tumor, which significantly differs from conventional HCC. This article reviews the molecular cytogenetics, pathology, imaging features, and management of this relatively rare tumor.
  
  
  CONCLUSIONS
  Fibrolamellar HCC predominantly occurs in young patients without underlying hepatitis or cirrhosis. Serum α-fetoproteins are not elevated in most cases, and hence imaging plays an important role in diagnosis, staging, and surveillance.
authors.affiliation: 1 Division of Diagnostic Imaging, Body Imaging Section, Unit 1473, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030-4009.
authors.forename: Dhakshinamoorthy
authors.initials: D
authors.lastname: Ganeshan
authors.forename: Janio
authors.initials: J
authors.lastname: Szklaruk
authors.forename: Vikas
authors.initials: V
authors.lastname: Kundra
authors.forename: Ahmed
authors.initials: A
authors.lastname: Kaseb
authors.forename: Asif
authors.initials: A
authors.lastname: Rashid
authors.forename: Khaled M
authors.initials: KM
authors.lastname: Elsayes
authors.forename: Khaled
authors.initials: K
authors.lastname: Elsayes
mesh_terms: D000293:Adolescent; D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D049268:Positron-Emission Tomography / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014463:Ultrasonography / Q000379:methods*; D055815:Young Adult