title: Visualizing ultrasonically induced shear wave propagation using phase-sensitive optical coherence tomography for dynamic elastography.
abstract: We report on the use of phase-sensitive optical coherence tomography (PhS-OCT) to detect and track temporal and spatial shear wave propagation within tissue, induced by ultrasound radiation force. Kilohertz-range shear waves are remotely generated in samples using focused ultrasound emission and their propagation is tracked using PhS-OCT. Cross-sectional maps of the local shear modulus are reconstructed from local estimates of shear wave speed in tissue-mimicking phantoms. We demonstrate the feasibility of combining ultrasound radiation force and PhS-OCT to perform high-resolution mapping of the shear modulus.
authors.forename: Thu-Mai
authors.initials: TM
authors.lastname: Nguyen
authors.forename: Shaozhen
authors.initials: S
authors.lastname: Song
authors.forename: Bastien
authors.initials: B
authors.lastname: Arnal
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Huang
authors.forename: Matthew
authors.initials: M
authors.lastname: O'Donnell
authors.forename: Ruikang K
authors.initials: RK
authors.lastname: Wang
mesh_terms: D001696:Biomechanical Phenomena; D054459:Elasticity Imaging Techniques / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D055595:Mechanical Phenomena; D019047:Phantoms, Imaging; D041623:Tomography, Optical Coherence / Q000379:methods*