title: Potential for use of the Seegene Anyplex MTB/NTM real-time detection assay in a regional reference laboratory.
abstract: Requests for direct molecular diagnosis of mycobacterial disease are increasingly warranted. The Anyplex MTB/NTM assay demonstrates sensitivities, specificities, and positive and negative predictive values of 1.00, 0.96, 0.93, and 1.00 for Mycobacterium tuberculosis complex (MTBC) and 1.00, 0.97, 0.75, and 1.00 for nontuberculous mycobacteria (NTM) detection, respectively, making it a suitable screening test for mycobacterial detection.
authors.affiliation: Public Health Wales Microbiology Cardiff, University Hospital of Wales, Heath Park, Cardiff, United Kingdom.
authors.forename: Michael D
authors.initials: MD
authors.lastname: Perry
authors.forename: P Lewis
authors.initials: PL
authors.lastname: White
authors.forename: Michael
authors.initials: M
authors.lastname: Ruddy
mesh_terms: D009164:Mycobacterium Infections / Q000175:diagnosis* / Q000382:microbiology; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000382:microbiology; D009169:Mycobacterium tuberculosis / Q000235:genetics; D009170:Nontuberculous Mycobacteria / Q000235:genetics; D057089:Pathology, Molecular / Q000379:methods*; D011446:Prospective Studies; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000175:diagnosis* / Q000382:microbiology