title: [Multiparametric 3T MRI in the routine staging of prostate cancer].
abstract: OBJECTIVE
  To analyse the detection ability of a multiparametric 3T MRI with phased-array coil in comparison with the pathological data provided by the prostatectomy specimens.
  
  
  METHODS
  Prospective study of 30 months, including 74 patients for whom a diagnosis of prostate cancer had been made on randomized prostate biopsies, and all eligible to a radical prostatectomy. They all underwent multiparametric 3T MRI with pelvic phased-array coil including T2-weighted imaging (T2W), dynamic contrast-enhanced (DCE) and diffusion-weighted imaging (DWI) with an ADC mapping. Each gland was divided in octants. Three specific criteria have been sought (detection ability, capsular contact [CC] and extracapsular extension [ECE]), in comparison with the pathological data provided by the prostatectomy specimens.
  
  
  RESULTS
  Five hundred and ninety-two octants were considered with 124 significant tumors (volume ≥ 0.1cm(3)). The general ability of tumor detection had a sensitivity, specificity, PPV and NPV respectively to 72.3%, 87.4%, 83.2% and 78.5%. The estimate of the CC and ECE had a high negative predictive power with specificities and VPN respectively to 96.4% and 95.4% for CC, and 97.5 and 97.7% for ECE.
  
  
  CONCLUSIONS
  Multiparametric 3T MRI with pelvic phased-array coil appeared to be a reliable imaging technique in clinical and routine practice for the detection of localized prostate cancer. Estimation of the CC and millimeter ECE remains to be clarified, even if the negative predictive power for these parameters seems encouraging.
authors.affiliation: Service d'urologie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Largeron
authors.affiliation: Service d'urologie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France.
authors.forename: F
authors.initials: F
authors.lastname: Galonnier
authors.affiliation: Service d'urologie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France.
authors.forename: N
authors.initials: N
authors.lastname: Védrine
authors.affiliation: Service de radiologie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France.
authors.forename: A
authors.initials: A
authors.lastname: Alfidja
authors.affiliation: Service de radiologie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France; Faculté de médecine, université d'Auvergne, 28, place Henri-Dunant, BP 38, 63001 Clermont-Ferrand cedex 1, France.
authors.forename: L
authors.initials: L
authors.lastname: Boyer
authors.affiliation: Délégation recherche clinique et innovation, CHU de Clermont-Ferrand, villa annexe IFSI - rue Montalembert, 63000 Clermont-Ferrand, France.
authors.forename: B
authors.initials: B
authors.lastname: Pereira
authors.affiliation: Service d'urologie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France; Faculté de médecine, université d'Auvergne, 28, place Henri-Dunant, BP 38, 63001 Clermont-Ferrand cedex 1, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Boiteux
authors.affiliation: Faculté de médecine, université d'Auvergne, 28, place Henri-Dunant, BP 38, 63001 Clermont-Ferrand cedex 1, France; Département d'anatomopathologie, 58, rue Montalembert, 63003 Clermont-Ferrand, France.
authors.forename: J L
authors.initials: JL
authors.lastname: Kemeny
authors.affiliation: Service d'urologie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France; Faculté de médecine, université d'Auvergne, 28, place Henri-Dunant, BP 38, 63001 Clermont-Ferrand cedex 1, France. Electronic address: lguy@chu-clermontferrand.fr.
authors.forename: L
authors.initials: L
authors.lastname: Guy
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000368:Aged; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011446:Prospective Studies; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery
keywords: Anatomopathologie; Bilan d’extension; Cancer de la prostate; IRM; MRI; Pathology; Prostate cancer; Staging
vernacular_title: L'IRM 3 Tesla multi-paramétrique dans le staging du cancer prostatique en pratique courante.