title: Stevens-Johnson syndrome following use of metronidazole in a dental patient.
abstract: Metronidazole alone rarely causes Stevens-Johnson syndrome (SJS). We present a case of an elderly male patient who, following metronidazole use, developed neurological symptoms followed by pain and blisters on both soles, erythema of face and neck, scrotal itching and erosion, and hemorrhagic encrustation around the lips and oral mucous membrane. Initial neurological symptoms followed by mucocutaneous manifestation of SJS following metronidazole use is probably a new presentation of this case.
authors.affiliation: Department of Pharmacology, Burdwan Medical College, Burdwan, West Bengal, India.
authors.forename: Goutameswar
authors.initials: G
authors.lastname: Mazumdar
authors.affiliation: Department of Dermatology, Burdwan Medical College, Burdwan, West Bengal, India.
authors.forename: Koushik
authors.initials: K
authors.lastname: Shome
mesh_terms: D003752:Dental Health Services; D003990:Dibenzoxepins / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004917:Erythromycin / Q000008:administration & dosage / Q000627:therapeutic use; D015738:Famotidine / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D017676:Lichen Planus, Oral / Q000188:drug therapy; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D008795:Metronidazole / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D000069605:Olopatadine Hydrochloride; D013262:Stevens-Johnson Syndrome / Q000188:drug therapy / Q000209:etiology*; D014221:Triamcinolone / Q000008:administration & dosage
chemical_list: D003990:Dibenzoxepins; D008795:Metronidazole; D014221:Triamcinolone; D000069605:Olopatadine Hydrochloride; D015738:Famotidine; D004917:Erythromycin; D008775:Methylprednisolone
keywords: Metronidazole; Stevens-Johnson syndrome; neurological manifestation