title: The effect of chronic kidney disease on total hip arthroplasty.
abstract: Patients with chronic kidney disease (CKD) undergoing total hip arthroplasty (THA) were evaluated for risk of revision, surgical site infection (SSI), thromboembolic events, mortality and readmission. 20,720 primary TKA cases were included (smaller sample for readmission evaluation, N = 9322). The prevalence of CKD among THA patients was 6.1% (N = 1269). After adjustment for age, gender, race, general health, and diabetes, CKD patients were at 1.4 (95% confidence interval 1.1-1.8) increased risk of readmission within 90 days. The adjusted risks for revision (overall, aseptic, and septic), SSI (deep and superficial), deep vein thrombosis, pulmonary embolism, and mortality (30-day, 90-day, ever) were not significantly different between patients with CKD and those without CKD. However, increased risk for 90-day readmission underscores that CKD patients are a fundamentally different population of patients.
authors.affiliation: Southern California Permanente Medical Group, Department of Orthopaedic Surgery, Los Angeles, California.
authors.forename: Alexander
authors.initials: A
authors.lastname: Miric
authors.affiliation: Kaiser Permanente, Surgical Outcomes and Analysis Unit, Clinical Analysis, San Diego, California.
authors.forename: Maria C S
authors.initials: MC
authors.lastname: Inacio
authors.affiliation: Southern California Permanente Medical Group, Department of Orthopaedic Surgery, Orange County, Irvine, California.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Namba
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000401:mortality / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010359:Patient Readmission; D012042:Registries; D051436:Renal Insufficiency, Chronic / Q000150:complications; D012086:Reoperation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000209:etiology; D013923:Thromboembolism / Q000209:etiology
keywords: hip arthroplasty; implant longevity; kidney disease; mortality; perioperative morbidity; total joint registry