title: Oral presentation of 10 patients with Cowden syndrome.
abstract: Cowden syndrome (CS) is an autosomal dominant genodermatosis that frequently affects several tissues with hamartomatous growth. The oral cavity is quite commonly involved with papillomatous lesions, which can be crucial to early diagnosis of this disease. In this series, 10 patients with a great diversity of manifestations associated with CS are presented, in whom oral papillomatosis was a constant and relevant finding to establish the diagnosis of CS. The role of the dentist in recognizing the oral lesions, the other diagnostic criteria, the risk for the development of malignancies, and the importance of lifetime follow-up are discussed.
authors.affiliation: Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.
authors.forename: Isadora Luana
authors.initials: IL
authors.lastname: Flores
authors.affiliation: Faculty of Stomatology, Autonomous University of San Luis Potosí, San Luis Potosí, Mexico.
authors.forename: Saray Aranda
authors.initials: SA
authors.lastname: Romo
authors.affiliation: Faculty of Stomatology, Autonomous University of San Luis Potosí, San Luis Potosí, Mexico.
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Tejeda Nava
authors.affiliation: Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.
authors.forename: Alan
authors.initials: A
authors.lastname: Roger dos Santos Silva
authors.affiliation: Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.
authors.forename: Pablo Agustin
authors.initials: PA
authors.lastname: Vargas
authors.affiliation: Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.
authors.forename: Oslei
authors.initials: O
authors.lastname: Paes de Almeida
authors.affiliation: Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil. Electronic address: malopes@fop.unicamp.br.
authors.forename: Márcio Ajudarte
authors.initials: MA
authors.lastname: Lopes
mesh_terms: D000328:Adult; D001706:Biopsy; D003113:Colonoscopy; D003937:Diagnosis, Differential; D005260:Female; D006223:Hamartoma Syndrome, Multiple / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000473:pathology