title: Stevens-Johnson syndrome: report on a case with a strange complaint of allergy to bus.
abstract: Stevens-Johnson syndrome is an uncommon inflammatory skin disorder in which immune mechanisms, cytotoxic reactions, and delayed hypersensitivity seem to be involved. Herein, an unusual case with strange complaint of"bus allergy" is presented, suffering from severe generalized itching and skin lesions, followed by ulcers in his mouth and genitalia. The diagnosis of Stevens-Johnson syndrome was made and appropriate treatment was advised. However, detailed medical history revealed a completely different cause of his allergic reactions, as he had occasionally used dimenhydrinate because of motion sickness in his history. Therefore, adverse drug reaction to dimenhydrinate was considered as the main underlying cause of the disease. In conclusion, thorough medical history should be taken to make a definitive diagnosis and identify the underlying disease, since accurate diagnosis and appropriate treatment can prevent further complications.
authors.affiliation: Noncommunicable Pediatric Diseases Research Center, Babol University of Medical Sciences, Babol.
authors.forename: Iraj
authors.initials: I
authors.lastname: Mohammadzadeh
authors.affiliation: Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mojdeh
authors.initials: M
authors.lastname: Khaledi
authors.affiliation: Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Nima
authors.initials: N
authors.lastname: Rezaei
mesh_terms: D000293:Adolescent; D000932:Antiemetics / Q000009:adverse effects*; D004111:Dimenhydrinate / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D008297:Male; D018986:Motor Vehicles; D013262:Stevens-Johnson Syndrome / Q000150:complications*; D014195:Travel
chemical_list: D000932:Antiemetics; D004111:Dimenhydrinate