title: Complete pseudoepiphyses with associated enhanced growth in hands and feet: a report of 2 siblings--case report.
abstract: We present 2 siblings with multiple complete pseudoepiphyses in their hands and feet with associated symptomatic enhanced growth. Physical examination of the 6-year-old boy revealed long slender fingers and hyperplastic great toes. Radiography showed complete pseudoepiphyses in the first metacarpals, proximal and middle phalanges of the hands, and proximal phalanges of the feet. The patient's younger brother had a similar phenotype with slightly milder functional complaints. Genetic analysis did not reveal an underlying syndrome in these siblings.
authors.affiliation: Department of Plastic and Reconstructive Surgery and Hand Surgery, Isala Klinieken, Zwolle, Netherlands. Electronic address: t.r.de.jong@isala.nl.
authors.forename: Tjeerd R
authors.initials: TR
authors.lastname: de Jong
authors.affiliation: Department of Plastic and Reconstructive Surgery and Hand Surgery, Isala Klinieken, Zwolle, Netherlands.
authors.forename: Wynand B W H
authors.initials: WB
authors.lastname: Melenhorst
authors.affiliation: Department of Plastic and Reconstructive Surgery and Hand Surgery, Isala Klinieken, Zwolle, Netherlands.
authors.forename: Peter
authors.initials: P
authors.lastname: Houpt
mesh_terms: D002648:Child; D004838:Epiphyses / Q000002:abnormalities* / Q000000981:diagnostic imaging; D005528:Foot / Q000000981:diagnostic imaging / Q000254:growth & development*; D006225:Hand / Q000000981:diagnostic imaging / Q000254:growth & development*; D006801:Humans; D008297:Male; D050279:Metacarpal Bones / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery; D008682:Metatarsal Bones / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery; D011859:Radiography; D035781:Siblings
keywords: Complete pseudoepiphysis; arachnodactyly; double epiphyses; enhanced growth; hyperplastic great toes