title: ANTIDotE: anti-tick vaccines to prevent tick-borne diseases in Europe.
abstract: Ixodes ricinus transmits bacterial, protozoal and viral pathogens, causing disease and forming an increasing health concern in Europe. ANTIDotE is an European Commission funded consortium of seven institutes, which aims to identify and characterize tick proteins involved in feeding and pathogen transmission. The knowledge gained will be used to develop and evaluate anti-tick vaccines that may prevent multiple human tick-borne diseases. Strategies encompassing anti-tick vaccines to prevent transmission of pathogens to humans, animals or wildlife will be developed with relevant stakeholders with the ultimate aim of reducing the incidence of tick-borne diseases in humans.
authors.affiliation: The National Institute of Public Health and the Environment (RIVM), Bilthoven, The Netherlands. hein.sprong@rivm.nl.
authors.forename: Hein
authors.initials: H
authors.lastname: Sprong
authors.forename: Jos
authors.initials: J
authors.lastname: Trentelman
authors.forename: Ingar
authors.initials: I
authors.lastname: Seemann
authors.forename: Libor
authors.initials: L
authors.lastname: Grubhoffer
authors.forename: Ryan O M
authors.initials: RO
authors.lastname: Rego
authors.forename: Ondřej
authors.initials: O
authors.lastname: Hajdušek
authors.forename: Petr
authors.initials: P
authors.lastname: Kopáček
authors.forename: Radek
authors.initials: R
authors.lastname: Šíma
authors.forename: Ard M
authors.initials: AM
authors.lastname: Nijhof
authors.forename: Juan
authors.initials: J
authors.lastname: Anguita
authors.forename: Peter
authors.initials: P
authors.lastname: Winter
authors.forename: Bjorn
authors.initials: B
authors.lastname: Rotter
authors.forename: Sabina
authors.initials: S
authors.lastname: Havlíková
authors.forename: Boris
authors.initials: B
authors.lastname: Klempa
authors.forename: Theo P
authors.initials: TP
authors.lastname: Schetters
authors.forename: Joppe W R
authors.initials: JW
authors.lastname: Hovius
mesh_terms: D000818:Animals; D000931:Antidotes; D060829:Arthropod Proteins / Q000276:immunology* / Q000302:isolation & purification; D005060:Europe / Q000453:epidemiology; D006801:Humans; D013984:Tick Infestations / Q000453:epidemiology / Q000517:prevention & control*; D017282:Tick-Borne Diseases / Q000453:epidemiology / Q000517:prevention & control*; D013987:Ticks / Q000276:immunology*; D014612:Vaccines
chemical_list: D000931:Antidotes; D060829:Arthropod Proteins; D014612:Vaccines