title: [Timing and efficacy of surgical intervention for severe acute pancreatitis].
abstract: OBJECTIVE
  To explore the indications, timing and approaches of surgical interventions for severe acute pancreatitis (SAP).
  
  
  METHODS
  A retrospective study was performed for 115 hospitalized SAP patients from 2007 to 2013.
  
  
  RESULTS
  Among them, 62 underwent surgery and another 53 were treated conservatively. The curative and mortality rates of surgical intervention and non-operation groups were 87.1%vs 84.9% (P > 0.05) and 9.68% vs 9.43% (P > 0.05) respectively. Twenty-five patients received early surgical intervention (<2 week) and another 37 delayed surgical intervention. The interval from diagnosis to surgical intervention of two groups were 7.5 ± 3.3 and 23.9 ± 8.5 days respectively. The mortality rates of early and delayed surgical groups were 16.0% and 5.4% respectively (P > 0.05).
  
  
  CONCLUSIONS
  Individualized comprehensive therapy should be offered in the treatment of SAP. Timing of surgery for those with pancreatic necrosis and infection should be delayed to 3-4 weeks later until their general conditions permit.
authors.affiliation: Department of General Surgery, Zhejiang Provincial People's Hospital, Hangzhou 310014, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Gastrointestinal Surgery, Zhejiang Provincial People's Hospital, Hangzhou 310014, China. Email: yangjin-lu@126.com.
authors.forename: Qin-shu
authors.initials: QS
authors.lastname: Shao
authors.forename: Ji
authors.initials: J
authors.lastname: Xu
authors.forename: Xiao-jun
authors.initials: XJ
authors.lastname: Yu
authors.forename: Yuan
authors.initials: Y
authors.lastname: Xu
authors.forename: Hou-quan
authors.initials: HQ
authors.lastname: Tao
authors.forename: Hai-bo
authors.initials: HB
authors.lastname: Yao
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D010180:Pancreatectomy; D019283:Pancreatitis, Acute Necrotizing / Q000601:surgery*; D012189:Retrospective Studies; D013997:Time Factors