title: Synthesis of chiral α-diarylacetic esters by stereospecific 1,2-aryl migration promoted by in situ generated acetals from benzoins.
abstract: A simple protocol for the synthesis of α-diarylacetic esters from benzoins is described. In situ generated acetal assists rapid 1,2-aryl migration in a stereospecific manner, paving the way to make enantioenriched α-diarylacetic esters from easily accessible enantiopure benzoins.
authors.affiliation: School of Chemistry, University of Hyderabad , Dr. C. R. Rao Road, Gachibowli, Hyderabad 500046, India.
authors.forename: Raveendra Babu
authors.initials: RB
authors.lastname: Kothapalli
authors.forename: Ramana
authors.initials: R
authors.lastname: Niddana
authors.forename: Rengarajan
authors.initials: R
authors.lastname: Balamurugan
mesh_terms: D000080:Acetals / Q000737:chemistry*; D000085:Acetates / Q000138:chemical synthesis* / Q000737:chemistry; D001573:Benzoin / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D004952:Esters; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000080:Acetals; D000085:Acetates; D004952:Esters; D007659:Ketones; D001573:Benzoin