title: Catalytic C-CN bond activation.
abstract: Synthetic organic reactions through C-CN activation by transition metal catalysis are reviewed. C-CN bond activation by metal complexes proceeds mainly via two pathways; oxidative addition and C-CN cleavage accompanied by silylisonitrile formation. Both the elemental reactions have been successfully applied to the catalytic reactions, including hydrodecyanation of nitriles, cross-coupling using nitriles as electrophiles, cyanation of aryl halides and arenes using organic nitriles as cyanating agents, and carbocyanation of unsaturated compounds.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, 615-8510, Japan, nakao.yoshiaki.8n@kyoto-u.ac.jp.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nakao