title: A case of catastrophic antiphospholipid syndrome, which presented an acute interstitial pneumonia-like image on chest CT scan.
abstract: We report the case of catastrophic antiphospholipid syndrome (CAPS) complicated with mixed connective tissue disease (MCTD). A female patient was diagnosed with acute interstitial pneumonia (AIP) with MCTD by chest CT scan. Corticosteroid therapy was refractory for lung involvement, and she died due to acute respiratory failure. The autopsy revealed that AIP was compatible with lung involvement of CAPS. We therefore suggest that chest CT might reveal AIP-like findings in CAPS patients whose condition is complicated with pulmonary manifestations.
authors.affiliation: Division of Endocrinology and Metabolism, Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University , Kagawa , Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Kameda
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Dobashi
authors.forename: Kentaro
authors.initials: K
authors.lastname: Susaki
authors.forename: Junichi
authors.initials: J
authors.lastname: Danjo
authors.forename: Shusaku
authors.initials: S
authors.lastname: Nakashima
authors.forename: Hiromi
authors.initials: H
authors.lastname: Shimada
authors.forename: Miharu
authors.initials: M
authors.lastname: Izumikawa
authors.forename: Yohei
authors.initials: Y
authors.lastname: Takeuchi
authors.forename: Hiroki
authors.initials: H
authors.lastname: Mitsunaka
authors.forename: Shuji
authors.initials: S
authors.lastname: Bandoh
authors.forename: Osamu
authors.initials: O
authors.lastname: Imataki
authors.forename: Masato
authors.initials: M
authors.lastname: Nose
authors.forename: Takuya
authors.initials: T
authors.lastname: Matsunaga
mesh_terms: D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging* / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D008947:Mixed Connective Tissue Disease / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography
keywords: Acute interstitial pneumonia; Catastrophic antiphospholipid syndrome; Mixed connective tissue disease