title: Effect of chlorine dioxide and sodium hypochlorite on the dissolution of human pulp tissue - An in vitro study.
abstract: BACKGROUND
  Organic tissue dissolution is an important property of an irrigant which aids in the success of root canal treatment. Recent studies have advocated the use of Chlorine dioxide as an endodontic irrigant. The aim of this study is to compare the dissolution efficacy of chlorine dioxide and sodium hypochlorite on human pulp tissue.
  
  
  METHODS
  In this study, 2% Sodium hypochlorite, 5% Chlorine dioxide and isotonic saline solution (control) were used. Thirty human pulp tissue specimens were exposed to three test solutions (n = 10) for 30 min following which the loss of weight was compared from the original weight by using a digital analytical balance.
  
  
  RESULTS
  Sodium hypochlorite was more efficient in dissolving human pulp tissue when compared to Chlorine dioxide. Isotonic saline solution failed to dissolve any of the specimens.
  
  
  CONCLUSIONS
  5% Chlorine dioxide is capable of dissolving human pulp tissue but sodium hypochlorite was more effective.
authors.affiliation: Dental Officer, 336 Field Hospital, C/O 56 APO, Saugor 470001, India.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Singh
authors.affiliation: Professor, Department of Oral and Maxillofacial Surgery, Sri Sai College of Dental Surgery, Kothrepally, Vikarabad, Hyderabad 501101, India.
authors.forename: Ramen
authors.initials: R
authors.lastname: Sinha
authors.affiliation: Commanding Officer, 336 Field Hospital, C/O 56 APO, Saugor 470001, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Kar
authors.affiliation: Assistant Professor, Manipal College of Dental Sciences, Manipal University, Manipal 576104, India.
authors.forename: Amber
authors.initials: A
authors.lastname: Ather
authors.affiliation: Professor, Department of Chemistry, Dr. Harisingh Gour University, Saugor 470001, India.
authors.forename: S N
authors.initials: SN
authors.lastname: Limaye
keywords: Chlorine dioxide; Pulp tissue dissolution; Sodium hypochlorite