title: D3, the new diffractometer for the macromolecular crystallography beamlines of the Swiss Light Source.
abstract: A new diffractometer for microcrystallography has been developed for the three macromolecular crystallography beamlines of the Swiss Light Source. Building upon and critically extending previous developments realised for the high-resolution endstations of the two undulator beamlines X06SA and X10SA, as well as the super-bend dipole beamline X06DA, the new diffractometer was designed to the following core design goals. (i) Redesign of the goniometer to a sub-micrometer peak-to-peak cylinder of confusion for the horizontal single axis. Crystal sizes down to at least 5 µm and advanced sample-rastering and scanning modes are supported. In addition, it can accommodate the new multi-axis goniometer PRIGo (Parallel Robotics Inspired Goniometer). (ii) A rapid-change beam-shaping element system with aperture sizes down to a minimum of 10 µm for microcrystallography measurements. (iii) Integration of the on-axis microspectrophotometer MS3 for microscopic sample imaging with 1 µm image resolution. Its multi-mode optical spectroscopy module is always online and supports in situ UV/Vis absorption, fluorescence and Raman spectroscopy. (iv) High stability of the sample environment by a mineral cast support construction and by close containment of the cryo-stream. Further features are the support for in situ crystallization plate screening and a minimal achievable detector distance of 120 mm for the Pilatus 6M, 2M and the macromolecular crystallography group's planned future area detector Eiger 16M.
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Martin R
authors.initials: MR
authors.lastname: Fuchs
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Claude
authors.initials: C
authors.lastname: Pradervand
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Vincent
authors.initials: V
authors.lastname: Thominet
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Roman
authors.initials: R
authors.lastname: Schneider
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Ezequiel
authors.initials: E
authors.lastname: Panepucci
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Marcel
authors.initials: M
authors.lastname: Grunder
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Jose
authors.initials: J
authors.lastname: Gabadinho
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Florian S N
authors.initials: FS
authors.lastname: Dworkowski
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Takashi
authors.initials: T
authors.lastname: Tomizaki
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Jörg
authors.initials: J
authors.lastname: Schneider
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Aline
authors.initials: A
authors.lastname: Mayer
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Adrian
authors.initials: A
authors.lastname: Curtin
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Vincent
authors.initials: V
authors.lastname: Olieric
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Uli
authors.initials: U
authors.lastname: Frommherz
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Goran
authors.initials: G
authors.lastname: Kotrle
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Jörg
authors.initials: J
authors.lastname: Welte
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Xinyu
authors.initials: X
authors.lastname: Wang
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Stephan
authors.initials: S
authors.lastname: Maag
authors.affiliation: DECTRIS Ltd, Neuenhoferstrasse 107, 5400 Baden, Switzerland.
authors.forename: Clemens
authors.initials: C
authors.lastname: Schulze-Briese
authors.affiliation: Swiss Light Source, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
authors.forename: Meitian
authors.initials: M
authors.lastname: Wang
keywords: beamline endstation; diffractometer; macromolecular crystallography; microcrystallography; microspectrophotometer