title: The association between endometriosis and chronic endometritis.
abstract: OBJECTIVE
  To evaluate the association between endometriosis and chronic endometritis.
  
  
  METHODS
  Endometrial specimens were obtained from 71 patients, 34 with endometriosis (endometriosis group) and 37 without endometriosis (non-endometriosis group), who underwent hysterectomy, and the specimens were immunostained for the plasmacyte marker CD138. The rate of chronic endometritis was compared between the endometriosis group and the non-endometriosis group. Furthermore, the 71 patients were also divided into two groups, 28 with chronic endometritis (chronic endometritis group) and 43 without chronic endometritis (non-chronic endometritis group). Logistic regression analysis was performed with variables including age, body mass index (BMI), gravidity and parity, and diagnoses of leiomyoma, adenomyosis, and endometriosis on pathology to examine the independent effect of each variable on chronic endometritis. Patients suffering from cervical invasive carcinoma, endometrial carcinoma, and endometrial polyps or treated with gonadotropin-releasing hormone agonists, progestins, or oral contraceptives before surgery were excluded.
  
  
  RESULTS
  Chronic endometritis was identified in 52.94% of the endometriosis group and 27.02% of the non-endometriosis group (p<0.05). Logistic regression analysis revealed that endometriosis was associated with chronic endometritis.
  
  
  CONCLUSIONS
  This result suggests a strong association between endometriosis and chronic endometritis.
authors.affiliation: Department of Obstetrics and Gynecology, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, Japan.
authors.forename: Akie
authors.initials: A
authors.lastname: Takebayashi
authors.affiliation: Department of Obstetrics and Gynecology, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, Japan.
authors.forename: Fuminori
authors.initials: F
authors.lastname: Kimura
authors.affiliation: Department of Obstetrics and Gynecology, Takanohara Central Hospital, Nara-shi, Nara, Japan.
authors.forename: Yohei
authors.initials: Y
authors.lastname: Kishi
authors.affiliation: Department of Clinical Laboratory Medicine and Division of Diagnostic Pathology, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, Japan.
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Ishida
authors.affiliation: Department of Obstetrics and Gynecology, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, Japan.
authors.forename: Akimasa
authors.initials: A
authors.lastname: Takahashi
authors.affiliation: Department of Obstetrics and Gynecology, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, Japan.
authors.forename: Akiyoshi
authors.initials: A
authors.lastname: Yamanaka
authors.affiliation: Department of Community Perinatal Medicine, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Takahashi
authors.affiliation: Department of Obstetrics and Gynecology, Takanohara Central Hospital, Nara-shi, Nara, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Suginami
authors.affiliation: Department of Obstetrics and Gynecology, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Murakami
mesh_terms: D062788:Adenomyosis / Q000150:complications; D000328:Adult; D015992:Body Mass Index; D004715:Endometriosis / Q000150:complications* / Q000503:physiopathology*; D004716:Endometritis / Q000150:complications* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007889:Leiomyoma / Q000150:complications; D016015:Logistic Models; D008597:Menstrual Cycle; D008875:Middle Aged; D012044:Regression Analysis; D053668:Syndecan-1 / Q000737:chemistry; D014599:Uterus / Q000473:pathology
chemical_list: D053668:Syndecan-1