title: Polydactyly in the multiethnic 'Negev' population at southern Israel.
abstract: The objective of this study was to characterize the prevalence, ethnic mix, and associated malformations of polydactyly in a multiethnic population. A retrospective analysis of 189 polydactyly patients was carried out. The incidence of polydactyly was 0.5/1000 live births and was higher in the Bedouin population. Preaxial polydactyly was 10 times more prevalent in the Jewish population and sporadic, and postaxial polydactyly was more prevalent in the consanguineous Bedouin population and associated with other malformations. We conclude that the pathologies in embryogenesis leading to preaxial and postaxial polydactyly vary, with the former occurring sporadically compared with the latter, which predominates in consanguineous families and syndromes.
authors.affiliation: aPediatrics B Department, Sheba Medical Center, Safra Children's Hospital, Tel-Hashomer bDepartment of Pediatrics, Faculty of Medicine, Tel-Aviv University, Tel-Aviv cDepartment of Plastic and Reconstructive Surgery, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel.
authors.forename: Yonatan
authors.initials: Y
authors.lastname: Yeshayahu
authors.forename: Amiram
authors.initials: A
authors.lastname: Sagi
authors.forename: Eldad
authors.initials: E
authors.lastname: Silberstein
mesh_terms: D005260:Female; D006801:Humans; D015994:Incidence; D007557:Israel / Q000453:epidemiology; D008297:Male; D017689:Polydactyly / Q000208:ethnology* / Q000601:surgery; D012189:Retrospective Studies