title: Binding versus triggering riboswitches.
abstract: In this issue of Chemistry & Biology, Trausch and Batey report a discrepancy between ligand binding affinity and the effect of transcription termination in a THF riboswitch, raising some important questions about our current understanding of ligand-dependent RNA switches.
authors.affiliation: Department of Chemistry and Graduate School Chemical Biology, University of Konstanz, 78464 Konstanz, Germany. Electronic address: joerg.hartig@uni-konstanz.de.
authors.forename: Jörg S
authors.initials: JS
authors.lastname: Hartig
mesh_terms: D005493:Folic Acid Antagonists / Q000378:metabolism*; D011687:Purines / Q000378:metabolism*; D058928:Riboswitch; D013763:Tetrahydrofolates / Q000378:metabolism*
chemical_list: D005493:Folic Acid Antagonists; D011687:Purines; D058928:Riboswitch; D013763:Tetrahydrofolates; C030371:5,6,7,8-tetrahydrofolic acid