title: First report of plasmid-mediated fluoroquinolone efflux pump QepA in Escherichia coli clinical isolate ST68, in South America.
abstract: This is the first report of the presence of qepA1 efflux pump gene in Escherichia coli clinical isolate from Argentina, which was associated to other plasmid-mediated quinolone resistance determinants, such as aac(6')-Ib-cr and qnrB10 and also quinolone resistance determining regions mutations.
authors.affiliation: Dpto. de Microbiología, CABA, Universidad de Buenos Aires, Buenos Aires, Argentina; Universidad Industrial de Santander, Santander, Colombia.
authors.forename: Giovanna
authors.initials: G
authors.lastname: Rincón
authors.affiliation: Dpto. de Microbiología, CABA, Universidad de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Marcela
authors.initials: M
authors.lastname: Radice
authors.affiliation: Hospital Británico, Buenos Aires, Argentina.
authors.forename: Marta
authors.initials: M
authors.lastname: Giovanakis
authors.affiliation: Dpto. de Microbiología, CABA, Universidad de Buenos Aires, Buenos Aires, Argentina; Cátedra de Microbiología General, Universidad Nacional del Litoral, Santa Fe, Argentina. Electronic address: jdiconza@gmail.com.
authors.forename: Jose A
authors.initials: JA
authors.lastname: Di Conza
authors.affiliation: Dpto. de Microbiología, CABA, Universidad de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Gutkind
mesh_terms: D000369:Aged, 80 and over; D001118:Argentina; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D004927:Escherichia coli Infections / Q000382:microbiology*; D029968:Escherichia coli Proteins / Q000235:genetics*; D005260:Female; D006801:Humans; D010957:Plasmids / Q000235:genetics*
chemical_list: D004269:DNA, Bacterial; D029968:Escherichia coli Proteins; C524438:QepA protein, E coli
keywords: Fluoroquinolone resistance; PMQR; QRDR; qepA