title: Macrophage activation: glancing into diversity.
abstract: Macrophage activation is a crucial process for innate immunity as well as for tissue and metabolic homeostasis. In this issue of Immunity, Xue et al. (2014) extend our knowledge on macrophage activation and identify unique functional states, thus expanding the M1-M2 paradigm.
authors.affiliation: Department of Experimental Oncology, European Institute of Oncology (IEO), Milan 20141, Italy. Electronic address: gioacchino.natoli@ieo.eu.
authors.forename: Gioacchino
authors.initials: G
authors.lastname: Natoli
authors.affiliation: Institute for Research in Biomedicine (IRB), 6500 Bellinzona, Switzerland. Electronic address: silvia.monticelli@irb.usi.ch.
authors.forename: Silvia
authors.initials: S
authors.lastname: Monticelli
mesh_terms: D000818:Animals; D020869:Gene Expression Profiling; D006801:Humans; D008262:Macrophage Activation / Q000276:immunology*; D008954:Models, Biological; D059467:Transcriptome / Q000235:genetics*