title: Client characteristics as moderators of the relation between the therapeutic alliance and outcome in cognitive therapy for depression.
abstract: OBJECTIVE
  Little is known about the variability of the alliance-outcome correlation across identifiable client subsets. This question was explored in a sample of 60 clients receiving cognitive therapy for depression, from which an overall correlation of .23 was observed between alliance ratings and subsequent symptom change.
  
  
  METHODS
  We examined interactions between the observer-rated version of the Working Alliance Inventory-Short Observer-Rated version (WAI-O; Tracey & Kokotovic, 1989) and client demographics, features of depression, personality, and other clinical features in predicting subsequent symptom change.
  
  
  RESULTS
  After correcting for multiple comparisons, interactions between the WAI-O and the number of prior depressive episodes, as well as the severity of baseline anxiety symptoms, were significant predictors of symptom change. When both interactions were controlled for, number of prior depressive episodes emerged as a statistically significant moderator. The alliance predicted outcome in the subgroup of clients with 0-2 prior episodes (r = .52), but not in those with 3 or more prior episodes (r = -.02). These findings were obtained despite similar univariate distributions on the alliance and symptom change in the 2 subgroups.
  
  
  CONCLUSIONS
  Differences that were observed in the predictive relation of alliance to outcome as a function of number of prior episodes suggest that different therapy processes may account for change in these subgroups. If the pattern observed in the present study is replicated, it would suggest that the alliance-outcome association has been both under- and overestimated.
authors.affiliation: Department of Psychology, University of Pennsylvania.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Lorenzo-Luaces
authors.affiliation: Department of Psychology, University of Pennsylvania.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: DeRubeis
authors.affiliation: Harvard Medical School/McLean Hospital, Harvard University.
authors.forename: Christian A
authors.initials: CA
authors.lastname: Webb
mesh_terms: D000328:Adult; D015928:Cognitive Behavioral Therapy; D003866:Depressive Disorder / Q000523:psychology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010551:Personality; D011369:Professional-Patient Relations; D016896:Treatment Outcome