title: [Validation of Questionnaire "ESTA": designed to assess the satisfaction with antidepressant treatment. Spain].
abstract: BACKGROUND
  We have no questionnaires to assess satisfaction with antidepressant treatment, which affects the health related quality of life. The objective was to develop and validate a specific instrument to assess satisfaction with antidepressant treatment, determining convergent validity regarding clinical effectiveness, fulfillment of expectations, adherence and tolerability.
  
  
  METHODS
  Longitudinal observational study where 168 patients started antidepressant treatment and were followed for one year. The variables included adverse effects, compliance and intensity of depressive symptoms. The questionnaire for the Evaluation of Antidepressant Treatment Satisfaction (ESTA) consists of 11 items answered using Likert scale. We evaluated its reliability, construct validity and concurrent validity with conceptually related measures with the construct assessed.
  
  
  RESULTS
  The Cronbach's alpha statistic ranged between 0.936 and 0.951. In the factor analysis one factor accounted for 64.11% of the variance. The average score of the questionnaire ranged from 40.0 to 44.7 points, showing a negative correlation regarding the Hamilton scale (-0.321 / -0.601) and Montgomery-Asberg scale (-0.491 / -0.307). After a month, the antidepressant treatment satisfaction was 39.5 points in noncompliant patients and 44.3 in compliers. In those who had adverse effects was 39.2 versus 43.3 for those who had not. At the first visit (15 days) the score was 40.0, in a month 42.6, in 3 months 44.4 and in 6 months 44.5. These differences were statistically significant (p <0.05). In test-retest analysis, intraclass correlation coefficient was 0.908.
  
  
  CONCLUSIONS
  The questionnaire, designed to assess satisfaction with antidepressant treatment, is valid and reliable, and provides a patient-centered instrument which is complementary to the clinical assessment of the effectiveness of antidepressant treatment.
authors.forename: Jesús
authors.initials: J
authors.lastname: López-Torres Hidalgo
authors.forename: Yolanda
authors.initials: Y
authors.lastname: López Gallardo
authors.forename: Ignacio
authors.initials: I
authors.lastname: Párraga Martínez
authors.forename: José Maria
authors.initials: JM
authors.lastname: del Campo del Campo
authors.forename: Alejandro
authors.initials: A
authors.lastname: Villena Ferrer
authors.forename: Susana
authors.initials: S
authors.lastname: Morena Rayo
mesh_terms: D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D003863:Depression / Q000188:drug therapy*; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D017060:Patient Satisfaction; D015203:Reproducibility of Results; D013030:Spain; D011795:Surveys and Questionnaires
chemical_list: D000959:Antihypertensive Agents
vernacular_title: Satisfacción con el tratamiento antidepresivo: validación del cuestionario "ESTA"