title: Age - specific incidence rate change at breast Cancer and its different histopathologic subtypes in Iran and Western countries.
abstract: OBJECTIVE
  The aim of the present study was to determine the frequency and age-specific incidence rate of different histopathologic subtypes of breast cancer in Iran, and compare it to neighboring and Western countries and to discuss the probable effective main factors.
  
  
  METHODS
  National data from cancer registry for 6265 female breast cancer patients were studied in 10 histopathologic groups.
  
  
  RESULTS
  The most common tumor was ductal carcinoma (89%). The peak age - specific incidence rate of breast cancer in total, and for epithelial, non-epithelial and ductal carcinomas were all 50-59 years, and it decreased in older age. It is in contrast to US SEER report which shows the incidence increases in higher age.
  
  
  CONCLUSIONS
  Three main factors including younger age of Iranian patients, probable more ERN tumors and different histopathological profile of breast cancer in Iran might be considered and studied to explain different slope of breast cancer after menopause compared to other countries.
authors.affiliation: Maryam Sadat Hosseini, Maliheh Arab, Professor of Gyneco-Oncology, Preventative Gynecology Research Center (PGRC), Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Maryam Sadat
authors.initials: MS
authors.lastname: Hosseini
authors.affiliation: Maryam Sadat Hosseini, Maliheh Arab, Professor of Gyneco-Oncology, Preventative Gynecology Research Center (PGRC), Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Maliheh
authors.initials: M
authors.lastname: Arab
authors.affiliation: Behzad Nemati Honar, Assistant Professor of General Surgery. Preventative Gynecology Research Center (PGRC), Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Behzad
authors.initials: B
authors.lastname: Nemati Honar
authors.affiliation: Giti Noghabaei, General Physician, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Giti
authors.initials: G
authors.lastname: Noghabaei
authors.affiliation: Nazanin Safaei , Resident of Obstetrics and Gynecology, Preventative Gynecology Research Center (PGRC), Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Nazanin
authors.initials: N
authors.lastname: Safaei
authors.affiliation: Tahereh Ghasemi, Resident of Obstetrics and Gynecology, Preventative Gynecology Research Center (PGRC), Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Tahereh
authors.initials: T
authors.lastname: Ghasemi
authors.affiliation: Farah Farzaneh, Associate Professor of Gyneco-Oncology, Preventative Gynecology Research Center (PGRC), Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Farah
authors.initials: F
authors.lastname: Farzaneh
authors.affiliation: Tahereh Ashraf Ganjoie, Associate Professor of Gyneco-Oncology, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Tahereh
authors.initials: T
authors.lastname: Ashraf Ganjoie
keywords: Age groups; Breast cancer; Histopathology; Incidence