title: Mesenchymal stem cells from umbilical cord tissue as potential therapeutics for cardiomyodegenerative diseases - a review.
abstract: Heart failure is one of the leading causes of death worldwide. End stage disease often requires heart transplantation, which is hampered by donor organ shortage. Tissue engineering represents a promising alternative approach for cardiac repair. For the generation of artificial heart muscle tissue several cell types, scaffold materials and bioreactor designs are under investigation. In this review, the use of mesenchymal stem cells derived from human umbilical cord tissue (UCMSC) for cardiac tissue engineering will be discussed.
authors.affiliation: Department of Cardiac Surgery, Munich University Medical Center, Munich, Germany.
authors.forename: Trixi
authors.initials: T
authors.lastname: Hollweck
authors.affiliation: Department of Cardiac Surgery, Munich University Medical Center, Munich, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Hagl
authors.affiliation: Department of Cardiac Surgery, Munich University Medical Center, Munich, Germany.
authors.forename: Günther
authors.initials: G
authors.lastname: Eissner
keywords: Umbilical cord tissue; bioreactor; cardiac differentiation; mesenchymal stem cells; non-degradable scaffolds; polytetrafluorethylene; titanium