title: [Open versus laparoscopic radical prostatectomy: a French center experience].
abstract: OBJECTIVE
  To compare peri-operative outcomes of open radical prostatectomy (ORP) to laparoscopic radical prostatectomy (LRP) in a single French institution.
  
  
  METHODS
  Between 1998 and 2003, 72 patients underwent ORP followed by 279 LRP between 2003 and 2010 for a clinically localized prostate cancer. Demographic, peri-operative and pathological data in the ORP and LRP groups were analyzed and compared.
  
  
  RESULTS
  In the ORP group, compared to the LRP group, the following significant differences were found: patients were older (63.1 years versus 65.6), initial PSA was higher (10.2 ng/mL versus 6.7) and the proportion of T1c was higher (62.8 % versus 80.6 %). Operative blood loss (1500 mL versus 500) and length of hospitalization (9.0 days versus 6.3) were higher in the ORP group (P<0.001). Operative time was longer in the LRP group (250 min versus 160; P<0 .001). There was no significant difference regarding length of catheterization (average of 8.5 days). Anastomotic strictures were more frequent following ORP (P<0.001). Positive margins proportion in the ORP group (7.1 %) was lower than that observed in the LRP group (28.7 %) (P=0.001). Patients in the ORP group achieved early continence more frequently (P<0.01) but at 12 months postoperatively there was no significant difference.
  
  
  CONCLUSIONS
  Patients in the LRP group had lower operative blood losses and a shorter length of hospitalization. However, in the ORP group, operative time was shorter and positive margins rate was lower.
authors.affiliation: Service d'urologie, CHU de Poitiers, 2, rue de la Milétrie, 86000 Poitiers, France. Electronic address: elod.verdier@yahoo.fr.
authors.forename: E
authors.initials: E
authors.lastname: Verdier
authors.affiliation: Service d'urologie, CHU de Poitiers, 2, rue de la Milétrie, 86000 Poitiers, France.
authors.forename: B
authors.initials: B
authors.lastname: Doré
authors.affiliation: Service d'anatomo-cyto-pathologie, CHU de Poitiers, rue de la Milétrie, 86000 Poitiers, France.
authors.forename: G
authors.initials: G
authors.lastname: Fromont
authors.affiliation: Service d'urologie, centre hospitalier Camille-Guérin, rue Docteur-Luc-Montagnier, 86100 Chatellerault, France.
authors.forename: C
authors.initials: C
authors.lastname: Pirès
authors.affiliation: Service d'urologie, centre hospitalier Camille-Guérin, rue Docteur-Luc-Montagnier, 86100 Chatellerault, France.
authors.forename: B
authors.initials: B
authors.lastname: Lecoq
authors.affiliation: Service d'urologie, clinique de l'Alliance, boulevard Alfred-Nobel, BP 30729, 37542 Saint-Cyr-Sur-Loire cedex, France.
authors.forename: J-C
authors.initials: JC
authors.lastname: Dezael
authors.affiliation: Service d'urologie, CHU de Poitiers, 2, rue de la Milétrie, 86000 Poitiers, France.
authors.forename: J
authors.initials: J
authors.lastname: Irani
mesh_terms: D000368:Aged; D005602:France; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: Cancer de la prostate localisé; Localized prostate cancer; Open and laparoscopic prostatectomy; Prostatectomie radicale; Prostatectomie rétropubienne et laparoscopique; Radical prostatectomy
vernacular_title: Prostatectomie radicale ouverte versus laparoscopique: expérience d'un centre français.