title: [Leptospirosis after refurbishment of old buildings].
abstract: HISTORY AND DIAGNOSIS: A 30-year-old patient was hospitalised with fever and jaundice. No long-term medication was taken. The patient worked as a plumber in refurbishment projects. He presented with headaches, myalgia and arthralgia of varying location and a fever of 38.9 °C. Skin and sclerae were visibly jaundiced. His cardiovascular system was normal. Further routine examination did not reveal any additional signs.
  
  
  METHODS
  Having ruled out an acute gallbladder infection or mechanical obstruction of the bile ducts by abdominal ultrasound, an infectious etiology appeared likely, alongside possible toxicological and immunological reasons. Clinical history and diagnosis led to an urgent suspicion of leptospirosis which was confirmed by IgM titer rise within five days in ELISA.
  
  
  METHODS
  The patient was treated immediately with ceftriaxone. During his stay in the hospital, his fever, jaundice and subjective symptoms subsided. Initial pathological markers also showed a significant trend towards reversion to normal levels. The patient was discharged from the hospital without any symptoms after 16 days.
  
  
  CONCLUSIONS
  Leptospirosis is a significant differential diagnosis in patients with fever, jaundice, headaches and myalgia. Clinical history can provide vital clues for diagnosing this illness. Individuals that are prone to be exposed to water contaminated with rodent urine are at heightened risk of developing the disease. Climatic conditions such as heavy rainfalls or flooding also appear to increase the risk of infection.
authors.affiliation: Innere Medizin - Gastroenterologie, Krankenhaus Grafenau.
authors.forename: J
authors.initials: J
authors.lastname: Rügamer
authors.affiliation: Innere Medizin - Gastroenterologie, Krankenhaus Grafenau.
authors.forename: R
authors.initials: R
authors.lastname: Kaaden
authors.affiliation: Institut für Pathologie und Zytologie, Gemeinschaftspraxis am Klinikum Deggendorf.
authors.forename: W
authors.initials: W
authors.lastname: Mohren
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D001706:Biopsy; D002443:Ceftriaxone / Q000627:therapeutic use; D060389:Construction Industry; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008099:Liver / Q000473:pathology; D008297:Male; D008487:Medical History Taking; D009784:Occupational Diseases / Q000175:diagnosis* / Q000209:etiology*; D012307:Risk Factors; D014895:Weil Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000635:transmission*
chemical_list: D000907:Antibodies, Bacterial; D007075:Immunoglobulin M; D002443:Ceftriaxone
vernacular_title: Leptospirose nach Altbausanierung.