title: [Bacterial translocation: gap in the shield].
abstract: The gastrointestinal tract is not only regarded as a system where nutrient absorption takes place, but also as a vital barrier against intraluminal pathogens entering the circulation and the maintenance of immune homeostasis. Bacterial translocation is defined as the penetration of viable bacteria or bacterial compounds from the gastrointestinal tract to extraintestinal sites. This disorder has been described in several clinical conditions. The main promoting factors for bacterial translocation have been proposed to be changes in the intestinal microflora, mucosal barrier failure and defects in host immunity. The presence of bacterial translocation has been associated with higher complications and mortality rates; therefore it should be taken into account in the therapeutic strategies of patients with predisposing factors.
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar I. Sebészeti Klinika Budapest Üllői út 78. 1082.
authors.forename: Olivér
authors.initials: O
authors.lastname: Rosero
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar I. Sebészeti Klinika Budapest Üllői út 78. 1082.
authors.forename: Tibor
authors.initials: T
authors.lastname: Kovács
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar I. Sebészeti Klinika Budapest Üllői út 78. 1082.
authors.forename: Péter
authors.initials: P
authors.lastname: Onody
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar I. Sebészeti Klinika Budapest Üllői út 78. 1082.
authors.forename: László
authors.initials: L
authors.lastname: Harsányi
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar I. Sebészeti Klinika Budapest Üllői út 78. 1082.
authors.forename: Attila
authors.initials: A
authors.lastname: Szijártó
mesh_terms: D001120:Arginine / Q000008:administration & dosage; D016470:Bacteremia / Q000276:immunology* / Q000382:microbiology / Q000628:therapy; D018988:Bacterial Translocation / Q000276:immunology; D019587:Dietary Supplements; D004750:Enteral Nutrition; D041981:Gastrointestinal Tract / Q000276:immunology / Q000382:microbiology*; D005973:Glutamine / Q000008:administration & dosage; D006801:Humans; D007413:Intestinal Mucosa / Q000276:immunology / Q000382:microbiology*; D056692:Prebiotics; D019936:Probiotics / Q000008:administration & dosage; D018805:Sepsis / Q000276:immunology; D018746:Systemic Inflammatory Response Syndrome / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control*
chemical_list: D056692:Prebiotics; D005973:Glutamine; D001120:Arginine
keywords: bacterial translocation; bakteriális transzlokáció; bélflóra; bélrendszer; gut; intestinal flora; sepsis; szepszis
vernacular_title: Bakteriális transzlokáció: rés a pajzson.