title: Primary orbital neuroblastoma in a 1-month-old boy.
abstract: Neuroblastoma is a malignant tumor predominantly occurring in children and usually arising from the adrenal gland or sympathetic ganglia. We describe a neuroblastoma in a 1-month-old boy arising from his left orbital cavity. This tumor was refractory to chemotherapy or radiotherapy, requiring enucleation of the left eye for complete removal of the intraorbital tumor. Thereafter, he received high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation, and has been in complete remission for 3 years. Unlike neuroblastomas arising from the adrenal gland or sympathetic ganglia, primary orbital neuroblastoma may be refractory even in early infancy.
authors.affiliation: Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan.
authors.forename: Natsuko
authors.initials: N
authors.lastname: Inazawa
authors.forename: Naoki
authors.initials: N
authors.lastname: Hatakeyama
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Hori
authors.forename: Masaki
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Keita
authors.initials: K
authors.lastname: Igarashi
authors.forename: Hasegawa
authors.initials: H
authors.lastname: Tadashi
authors.forename: Jiro
authors.initials: J
authors.lastname: Ogino
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tsutsumi
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Suzuki
mesh_terms: D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009367:Neoplasm Staging / Q000379:methods*; D009447:Neuroblastoma / Q000175:diagnosis*; D009918:Orbital Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed
keywords: infant; neuroblastoma; orbital tumor