title: Laser Doppler projection tomography.
abstract: We propose a laser Doppler projection tomography (LDPT) method to obtain visualization of three-dimensional (3D) flowing structures. With LDPT, the flowing signal is extracted by a modified laser Doppler method, and the 3D flowing image is reconstructed by the filtered backprojection algorithm. Phantom experiments are performed to demonstrate that LDPT is able to obtain 3D flowing structure with higher signal-to-noise ratio and spatial resolution. Our experiment results display its potentially useful application to develop 3D label-free optical angiography for the circulation system of live small animal models or microfluidic experiments.
authors.forename: Yaguang
authors.initials: Y
authors.lastname: Zeng
authors.forename: Ke
authors.initials: K
authors.lastname: Xiong
authors.forename: Xuanlong
authors.initials: X
authors.lastname: Lu
authors.forename: Guanping
authors.initials: G
authors.lastname: Feng
authors.forename: Dingan
authors.initials: D
authors.lastname: Han
authors.forename: Jing
authors.initials: J
authors.lastname: Wu
mesh_terms: D000818:Animals; D001775:Blood Circulation; D021621:Imaging, Three-Dimensional; D007834:Lasers; D012542:Scattering, Radiation; D059629:Signal-To-Noise Ratio; D014054:Tomography / Q000379:methods*