title: The link between nutritional parameters and bone mineral density in women: results of a screening programme for osteoporosis.
abstract: BACKGROUND
  A positive association between handgrip strength and bone mineral density was demonstrated, but not all the investigations confirmed these results. We conducted a screening programme for osteoporosis in a large cohort of postmenopausal women to investigate the relationship between handgrip strength, other nutritional parameters and bone density.
  
  
  METHODS
  This investigation involved 1,300 white volunteers. All participants underwent a bone mineral density evaluation at the heel and a handgrip strength measurement.
  
  
  RESULTS
  The mean T-score value was -1.15 ± 1; a total of 181 participants reported at least one osteoporotic fracture. In the univariate analysis, both handgrip strength and body mass index were associated with the T-score value. Adjustment for confounding factors confirmed this relationship showing, in the multivariate analysis, that the body mass index was positively correlated to the T-score (B = 0.034; p = 0.001) and, in the logistic regression analysis, that handgrip strength was associated with the presence of osteoporosis (P = 0.005).
  
  
  CONCLUSIONS
  Both body mass index and handgrip strength were strongly correlated to bone mineral density, assessed with ultrasound, suggesting a possible key role as bone disease predictors.
authors.forename: Theodora
authors.initials: T
authors.lastname: Lamprinoudi
authors.forename: Elisa
authors.initials: E
authors.lastname: Mazza
authors.forename: Yvelise
authors.initials: Y
authors.lastname: Ferro
authors.forename: Simona
authors.initials: S
authors.lastname: Brogneri
authors.forename: Daniela
authors.initials: D
authors.lastname: Foti
authors.forename: Elio
authors.initials: E
authors.lastname: Gulletta
authors.forename: Maurizio
authors.initials: M
authors.lastname: Iocco
authors.forename: Carmine
authors.initials: C
authors.lastname: Gazzaruso
authors.forename: Stefano
authors.initials: S
authors.lastname: Romeo
authors.forename: Arturo
authors.initials: A
authors.lastname: Pujia
authors.affiliation: Clinical Nutrition Unit, Department of Medical and Surgical Science, University Magna Grecia, Catanzaro, Italy. tmontalcini@unicz.it.
authors.forename: Tiziana
authors.initials: T
authors.lastname: Montalcini
mesh_terms: D015519:Bone Density; D003710:Demography; D005260:Female; D006801:Humans; D016014:Linear Models; D008403:Mass Screening; D008875:Middle Aged; D015999:Multivariate Analysis; D009747:Nutritional Physiological Phenomena; D010024:Osteoporosis / Q000175:diagnosis* / Q000503:physiopathology*