title: Restoration of articular cartilage.
abstract: ➤ Novel (i.e., quantitative and semiquantitative) cartilage imaging techniques can evaluate cartilage composition to augment information obtained from traditional magnetic resonance imaging sequences that detail morphology.➤ A well-defined role for drugs leading to chondroprotection has not yet been determined.➤ Shortcomings of bone marrow stimulation include limited production of hyaline repair tissue, unpredictable repair cartilage volume, and a negative impact on later cellular transplantation if required.➤ The role of biological augments, such as cellular concentrates or platelet-rich plasma, remains undefined. When their use is reported in the literature, it is important that their process of production and characterization be detailed.➤ Rehabilitation programs, incorporating controlled exercise and progressive partial weight-bearing, are an important part of cartilage repair surgery and should be detailed in reports on operative techniques applied.➤ Malalignment, meniscal injury, and ligament deficiency should be corrected in a staged or concomitant fashion to reduce the overall likelihood of mechanical failure in cartilage repair surgery.
authors.affiliation: Sports Medicine and Shoulder Service (C.J.M., C.P.-G., R.F.W., and S.A.R.) and Department of Radiology and Imaging (H.G.P.), Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021. E-mail address for C.J. Moran: cathaljmoran@gmail.com.
authors.forename: Cathal J
authors.initials: CJ
authors.lastname: Moran
authors.affiliation: Sports Medicine and Shoulder Service (C.J.M., C.P.-G., R.F.W., and S.A.R.) and Department of Radiology and Imaging (H.G.P.), Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021. E-mail address for C.J. Moran: cathaljmoran@gmail.com.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Pascual-Garrido
authors.affiliation: Department of Biochemistry, Rush University Medical Center, Cohn Research Building, Suite 522, 1735 West Harrison Street, Chicago, IL 60612.
authors.forename: Susan
authors.initials: S
authors.lastname: Chubinskaya
authors.affiliation: Sports Medicine and Shoulder Service (C.J.M., C.P.-G., R.F.W., and S.A.R.) and Department of Radiology and Imaging (H.G.P.), Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021. E-mail address for C.J. Moran: cathaljmoran@gmail.com.
authors.forename: Hollis G
authors.initials: HG
authors.lastname: Potter
authors.affiliation: Sports Medicine and Shoulder Service (C.J.M., C.P.-G., R.F.W., and S.A.R.) and Department of Radiology and Imaging (H.G.P.), Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021. E-mail address for C.J. Moran: cathaljmoran@gmail.com.
authors.forename: Russell F
authors.initials: RF
authors.lastname: Warren
authors.affiliation: Division of Sports Medicine, Cartilage Restoration Center, Midwest Orthopedics at Rush, Rush University Medical Center, 1611 West Harrison Street, Suite 300, Chicago, IL 60612.
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Cole
authors.affiliation: Sports Medicine and Shoulder Service (C.J.M., C.P.-G., R.F.W., and S.A.R.) and Department of Radiology and Imaging (H.G.P.), Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021. E-mail address for C.J. Moran: cathaljmoran@gmail.com.
authors.forename: Scott A
authors.initials: SA
authors.lastname: Rodeo
mesh_terms: D002358:Cartilage, Articular / Q000293:injuries / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008592:Menisci, Tibial / Q000473:pathology* / Q000601:surgery; D000070600:Tibial Meniscus Injuries