title: Ratiometric fluorescence assay for γ-glutamyltranspeptidase detection based on a single fluorophore via analyte-induced variation of substitution.
abstract: The first ratiometric fluorescent probe for γ-glutamyltranspeptidase (GGT) was developed, which functions through GGT-induced variation of substitution and subsequent changes in photophysical properties. It can detect GGT in human serum, and be used to visualize the endogenous GGT in ovarian cancer cells.
authors.affiliation: College of Materials Science & Engineering, State Key Lab of Luminescent Materials & Devices, South China University of Technology, Guangzhou 510640, P. R. China. mcfzeng@scut.edu.cn shzhwu@scut.edu.cn.
authors.forename: Xianfeng
authors.initials: X
authors.lastname: Hou
authors.forename: Qingxiang
authors.initials: Q
authors.lastname: Yu
authors.forename: Fang
authors.initials: F
authors.lastname: Zeng
authors.forename: Changmin
authors.initials: C
authors.lastname: Yu
authors.forename: Shuizhu
authors.initials: S
authors.lastname: Wu
mesh_terms: D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D005723:gamma-Glutamyltransferase / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D005723:gamma-Glutamyltransferase