title: Contact pressure-aided spectroscopy.
abstract: Contact pressure induced by manually operated fiber optic probes can significantly affect the optical properties of the studied tissue. If the contact pressure and the changes in optical properties are measured properly, then the complementary information can be used to obtain additional insight into the tissue physiology. However, as reliable assessment of the contact pressure in the existing diffuse reflectance setups is difficult, the impact of contact pressure is usually neglected or considered as a source of errors. We introduce a measurement system for controlled application of contact pressure and for the acquisition of diffuse reflectance spectra, which is suitable for in vivo studies and for overcoming the limitations of the existing measurement setups. A spectral-contact-pressure plane is proposed to present the combined information, highlighting the unique tissue response to the applied pressure.
authors.affiliation: University of Ljubljana, Faculty of Electrical Engineering, Laboratory of Imaging Technologies, Tržaška cesta 25, 1000, Ljubljana, Slovenia.
authors.forename: Maksimilijan
authors.initials: M
authors.lastname: Bregar
authors.affiliation: University of Ljubljana, Faculty of Electrical Engineering, Laboratory of Imaging Technologies, Tržaška cesta 25, 1000, Ljubljana, Slovenia.
authors.forename: Miran
authors.initials: M
authors.lastname: Bürmen
authors.affiliation: University of Ljubljana, Faculty of Electrical Engineering, Laboratory of Microsensor Structures and Electronics, Tržaška cesta 25, 1000, Ljubljana, Slovenia.
authors.forename: Uroš
authors.initials: U
authors.lastname: Aljancic
authors.affiliation: University of Ljubljana, Faculty of Electrical Engineering, Laboratory of Imaging Technologies, Tržaška cesta 25, 1000, Ljubljana, Slovenia.
authors.forename: Blaž
authors.initials: B
authors.lastname: Cugmas
authors.affiliation: University of Ljubljana, Faculty of Electrical Engineering, Laboratory of Imaging Technologies, Tržaška cesta 25, 1000, Ljubljana, Slovenia.
authors.forename: Franjo
authors.initials: F
authors.lastname: Pernuš
authors.affiliation: University of Ljubljana, Faculty of Electrical Engineering, Laboratory of Imaging Technologies, Tržaška cesta 25, 1000, Ljubljana, Slovenia.
authors.forename: Boštjan
authors.initials: B
authors.lastname: Likar
mesh_terms: D000818:Animals; D005336:Fiber Optic Technology / Q000295:instrumentation* / Q000379:methods; D005528:Foot / Q000502:physiology; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D011312:Pressure; D019265:Spectroscopy, Near-Infrared / Q000295:instrumentation / Q000379:methods*; D013552:Swine