title: Sleep disturbances and glucoregulation in patients with type 2 diabetes.
abstract: We investigated the frequency of sleep disturbances and the association between sleep disturbances and glucoregulation in type 2 diabetic patients. The frequency of sleep disturbances in 614 type 2 diabetic patients was investigated using validated sleep questionnaires. There were 381 male and 233 female patients. The mean age was 59.7 ± 11.1 yr; the mean body mass index was 24.9 ± 4.4 kg/m(2); the mean HbA1c was 7.8% ± 1.5%; and the mean duration of diabetes was 10.3 ± 8.4 yr. The questionnaires revealed insomnia in 48.2% of the patients while 8.5% reported excessive daytime sleepiness. A total of 49% of the patients was poor sleepers, while 28.5% had depression. Multivariate logistic regression analysis showed that there was no significant association between HbA1c and other sleep disturbances, such as poor sleep, insomnia, and short duration of sleep. Sleep disturbances were very common in patients with type 2 diabetes mellitus, whereas there was no association between poor or short sleep and glucoregulation. Awareness and identifying sleep complaints in such patients are necessary to improve their quality of daily life.
authors.affiliation: Department of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon, Korea.
authors.forename: Eun-Hee
authors.initials: EH
authors.lastname: Cho
authors.affiliation: Department of Preventive Medicine, Kangwon National University Hospital, Chuncheon, Korea.
authors.forename: HeyJean
authors.initials: H
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Ohk Hyun
authors.initials: OH
authors.lastname: Ryu
authors.affiliation: Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Moon Gi
authors.initials: MG
authors.lastname: Choi
authors.affiliation: Department of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon, Korea.
authors.forename: Sang-Wook
authors.initials: SW
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D003863:Depression / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D007319:Sleep Initiation and Maintenance Disorders / Q000453:epidemiology; D012893:Sleep Wake Disorders / Q000150:complications*; D011795:Surveys and Questionnaires
chemical_list: D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; C517652:hemoglobin A1c protein, human
keywords: Diabetes Mellitus; Glucose; Sleep Disorders