title: Recurrent gastrointestinal bleeding with ANCA associated glomerulonephritis successfully treated by transarterial embolization.
abstract: Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) is a group of autoimmune diseases that normally affects multiple organs. Recurrent gastrointestinal (GI) bleeding, a critical complication of AAV, remains a challenge. Here, we report a case of AAV complicated by pulmonary hemorrhage, severe recurrent gastrointestinal bleeding, and rapid progressive renal insufficiency that was treated successfully with selective transarterial embolization, continuous veno-venous hemofiltration, plasma exchange, intravenous gamma globulin infusion, followed by steroids and cytotoxic drug therapy. We report this case considering that selective transarterial embolization may be a safe and effective alternative method in recurrent AAV associated GI bleeding caused by AAV refractory to medical therapy.
authors.affiliation: Ling Li, Division of Nephrology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Li
authors.affiliation: Xiao Li, Division of Gastroenterology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Li
authors.affiliation: Ping Fu, Division of Nephrology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Fu
authors.affiliation: Fang Liu, Division of Nephrology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Liu
keywords: Anti-neutrophil cytoplasmic antibody-associated vasculitis; Gastrointestinal bleeding; Transarterial embolization