title: Intranodal leiomyoma in a young child: report of a rare spindle cell lesion.
abstract: ABSTRACT Primary spindle cell lesions of lymph nodes, with the exception of Kaposi's sarcoma, are rare. Intranodal palisaded myofibroblastoma has been described as a spindle cell tumor with prominent amianthoid fibers, intralesional hemorrhage, and intracellular or extracellular inclusions. Another spindle cell lesion, intranodal leiomyoma, has been reported only occasionally. We report the case of a 6-year-old boy with a mass in the neck without other systemic complaints. Excision biopsy of the lymph node revealed a spindle cell tumor with lymph nodal tissue at the periphery. The tumor showed features of smooth muscle differentiation with focally high mitotic index. The classical features of myofibroblastoma were not present. A final pathologic diagnosis of intranodal leiomyoma was rendered. The child has been free of recurrence in the follow-up period. Intranodal leiomyoma is a rare primary spindle cell lesion of the lymph nodes and should be considered in the differential diagnosis of the same.
authors.affiliation: 1   Assistant Professor and Head, Department of Otorhinolaryngology, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi - 110031, India.
authors.forename: Manish
authors.initials: M
authors.lastname: Girhotra
authors.forename: Shehbaaz Singh
authors.initials: SS
authors.lastname: Virk
authors.forename: Sarika
authors.initials: S
authors.lastname: Verma
authors.forename: Kalpana
authors.initials: K
authors.lastname: Bansal
authors.forename: Ruchika
authors.initials: R
authors.lastname: Gupta
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D006470:Hemorrhage / Q000473:pathology; D006801:Humans; D007889:Leiomyoma / Q000175:diagnosis / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008938:Mitosis / Q000502:physiology*; D009130:Muscle, Smooth / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000473:pathology; D009379:Neoplasms, Muscle Tissue / Q000175:diagnosis / Q000473:pathology*
keywords: cervical; child; intranodal; leiomyoma; mitosis