title: Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-κB signaling pathway.
authors.affiliation: Department of Neuropathology, University of Bonn, Sigmund-Freud-St. 25, 53105, Bonn, Germany, t.pietsch@uni-bonn.de.
authors.forename: Torsten
authors.initials: T
authors.lastname: Pietsch
authors.forename: Inken
authors.initials: I
authors.lastname: Wohlers
authors.forename: Tobias
authors.initials: T
authors.lastname: Goschzik
authors.forename: Verena
authors.initials: V
authors.lastname: Dreschmann
authors.forename: Dorota
authors.initials: D
authors.lastname: Denkhaus
authors.forename: Evelyn
authors.initials: E
authors.lastname: Dörner
authors.forename: Sven
authors.initials: S
authors.lastname: Rahmann
authors.forename: Ludger
authors.initials: L
authors.lastname: Klein-Hitpass
mesh_terms: D002648:Child; D002675:Child, Preschool; D004252:DNA Mutational Analysis; D004806:Ependymoma / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016328:NF-kappa B / Q000378:metabolism*; D011506:Proteins / Q000235:genetics* / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology*; D015173:Supratentorial Neoplasms / Q000235:genetics* / Q000473:pathology; D051996:Transcription Factor RelA / Q000235:genetics* / Q000378:metabolism; D014157:Transcription Factors
chemical_list: D016328:NF-kappa B; D011506:Proteins; D012333:RNA, Messenger; D051996:Transcription Factor RelA; C585140:ZFTA protein, human; D014157:Transcription Factors; C498143:RELA protein, human