title: Cohort Profile: French hospital database on HIV (FHDH-ANRS CO4).
abstract: The French Hospital Database on HIV (FHDH) is a hospital-based multicentre open cohort with inclusions ongoing since 1989. The research objectives focus mainly on mid- and long-term clinical outcomes and therapeutic strategies, as well as severe AIDS and non-AIDS morbidities, and public health issues relative to HIV infection. FHDH also serves to describe HIV-infected patients receiving hospital care in France. FHDH includes data on more than 120,000 HIV-infected patients from 70 French general or university hospitals distributed throughout France. Patients are eligible for inclusion if they are infected by HIV-1 or HIV-2 and give their written informed consent. Standardized variables are collected at each outpatient visit or hospital admission during which a new clinical manifestation is diagnosed, a new treatment is prescribed or a change in biological markers is noted, and/or at least every 6 months. Since its inception, variables collected in FHDH include demographic characteristics, HIV-related biological markers, the date and type of AIDS and non AIDS-defining events, antiretroviral treatments and the date and causes of death, as reported in the medical records. Since 2005, data have also been collected on: co-infection with hepatitis B or C virus; alcohol and tobacco use; and non HIV-related biomarkers. Anyone can submit a research project by completing a standardized form available on the FHDH website (http://www.ccde.fr/_fold/fl-1385734776-429.pdf) or from the corresponding author, describing the context and objectives of the study. All projects are reviewed by the scientific committee.
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authors.lastname: Mary-Krause
authors.forename: Sophie
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authors.lastname: Grabar
authors.forename: Laurence
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authors.lastname: Lièvre
authors.forename: Sophie
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authors.lastname: Abgrall
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authors.lastname: Billaud
authors.forename: François
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authors.lastname: Boué
authors.forename: Laurence
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authors.forename: Jacques
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authors.forename: Catherine
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authors.lastname: Gaud
authors.forename: Jacques
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authors.lastname: Gilquin
authors.forename: Marguerite
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authors.lastname: Guiguet
authors.forename: Christine
authors.initials: C
authors.lastname: Katlama
authors.forename: Marie-Aude
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authors.lastname: Khuong-Josses
authors.forename: Jean-Marc
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authors.lastname: Lacombe
authors.forename: Sylvie
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authors.lastname: Lang
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Lascaux
authors.forename: Odile
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authors.lastname: Launay
authors.forename: Aba
authors.initials: A
authors.lastname: Mahamat
authors.forename: Sophie
authors.initials: S
authors.lastname: Matheron
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Meynard
authors.forename: Juliette
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authors.lastname: Pavie
authors.forename: Fabrice
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authors.lastname: Pilorgé
authors.forename: Lionel
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authors.lastname: Piroth
authors.forename: Isabelle
authors.initials: I
authors.lastname: Poizot-Martin
authors.forename: Valérie
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authors.lastname: Potard
authors.forename: Christian
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authors.lastname: Pradier
authors.forename: Jacques
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authors.lastname: Reynes
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Rouveix
authors.forename: Hana
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authors.lastname: Selinger-Leneman
authors.forename: Anne
authors.initials: A
authors.lastname: Simon
authors.forename: Pierre
authors.initials: P
authors.lastname: Tattevin
authors.forename: Hervé
authors.initials: H
authors.lastname: Tissot-Dupont
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Viard
authors.forename: Nathalie
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authors.lastname: Viget
authors.forename: Dominique
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authors.lastname: Costagliola
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000453:epidemiology; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D015331:Cohort Studies; D060085:Coinfection; D016208:Databases, Factual / Q000706:statistics & numerical data*; D005260:Female; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology; D006505:Hepatitis / Q000150:complications* / Q000453:epidemiology; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
keywords: AIDS; FHDH; HIV; antiretroviral treatment; cohort; comorbidities