title: Xanthones from aerial parts of Hypericum laricifolium Juss.
abstract: From the aerial parts of Hypericum laricifolium Juss., twelve compounds were isolated and identified. They were the xanthones: 1-hydroxy-7-methoxy-xanthone (1), 1,7-dihydroxy-xanthone (2), 2-hydroxy-xanthone (3), 6-deoxyisojacareubin (4), 1,3-dihydroxy-6-methoxy-xanthone (6), and 1,5,6-trihydroxy-7-methoxy-xanthone (7), together with beta-sitosterol, betulinic acid, vanillic acid, isoquercitrin and a mixture of quercetin and isorhamnetin. All the compounds were characterized by spectroscopic and mass spectrometric methods, and by comparison with literature data. Thisis the first report on the presence of xanthones in H.laricifolium. 1,3-Dihydroxy-6-methoxy-xanthone has been previously synthesized, but this is the first report of its isolation from a natural source.
authors.affiliation: Instituto de Investigaciones, Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida. irama@ula.ve
authors.forename: Irama
authors.initials: I
authors.lastname: Ramírez-Gonzáilez
authors.affiliation: Laboratorio de Productos Naturales, Departamento de Química, Facultad de Ciencias, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela.
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Amaro-Luis
authors.affiliation: Laboratorio de Productos Naturales, Departamento de Química, Facultad de Ciencias, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela.
authors.forename: Alí
authors.initials: A
authors.lastname: Bahsas
mesh_terms: D020902:Hypericum / Q000737:chemistry*; D035261:Plant Components, Aerial / Q000737:chemistry; D044004:Xanthones / Q000302:isolation & purification*
chemical_list: D044004:Xanthones