title: Full outline of unresponsiveness score versus Glasgow Coma Scale in children with nontraumatic impairment of consciousness.
abstract: The study was designed to compare the Full Outline of UnResponsiveness score with Glasgow Coma Scale as a predictor of mortality and poor functional outcome at hospital discharge in children with nontraumatic impairment of consciousness. Seventy children aged 5 to 18 years admitted with impaired consciousness were enrolled. The scores were applied by the Pediatric Neurology fellow within 2 hours of admission. The primary outcome studied was in-hospital mortality. Receiver operating characteristic curves were used to compare the 2 scores. The area under the curves for Glasgow Coma Scale and Full Outline of UnResponsiveness scores were 0.916 and 0.940, respectively. However, the difference between the areas under curve for the 2 scores was not statistically significant (0.023; 95% confidence interval: -0.0115 to 0.058). Our data indicate that both the scores are good predictors for in-hospital mortality and functional outcome. However, no significant difference was observed between the ability of the 2 scores to predict the outcomes.
authors.affiliation: Department of Pediatrics, Division of Pediatric Neurology, All India Institute of Medical Sciences, New Delhi, India Department of Pediatric Neurology, SPS Apollo Hospital, Ludhiana (Punjab), India.
authors.forename: Gurpreet Singh
authors.initials: GS
authors.lastname: Kochar
authors.affiliation: Department of Pediatrics, Division of Pediatric Neurology, All India Institute of Medical Sciences, New Delhi, India sheffaligulati@gmail.com.
authors.forename: Sheffali
authors.initials: S
authors.lastname: Gulati
authors.affiliation: Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Lodha
authors.affiliation: Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Rm
authors.initials: R
authors.lastname: Pandey
mesh_terms: D000293:Adolescent; D019540:Area Under Curve; D002648:Child; D002675:Child, Preschool; D003244:Consciousness Disorders / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality*; D005260:Female; D015600:Glasgow Coma Scale; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D012372:ROC Curve
keywords: Full Outline of UnResponsiveness (FOUR) score; Glasgow Coma Scale (GCS); coma; impaired consciousness