title: Retrograde signaling causes excitement.
abstract: Retrograde signaling is a powerful tool to shape synaptic transmission, typically inducing inhibition of transmitter release. A new study published in this issue of Neuron by Carta et al. (2014) now provides strong support for arachidonic acid as a potentiating retrograde messenger.
authors.affiliation: Neurowissenschaftliches Forschungszentrum, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany; Bernstein Center for Computational Neuroscience Berlin, 10115 Berlin, Germany; Cluster of Excellence "NeuroCure," 10117 Berlin, Germany; DZNE-German Center for Neurodegenerative Diseases, 10117 Berlin, Germany. Electronic address: dietmar.schmitz@charite.de.
authors.forename: Dietmar
authors.initials: D
authors.lastname: Schmitz
authors.affiliation: Neurowissenschaftliches Forschungszentrum, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
authors.forename: Jörg
authors.initials: J
authors.lastname: Breustedt
authors.affiliation: Neurowissenschaftliches Forschungszentrum, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany; Bernstein Center for Computational Neuroscience Berlin, 10115 Berlin, Germany.
authors.forename: Anja
authors.initials: A
authors.lastname: Gundlfinger
mesh_terms: D000818:Animals; D006624:Hippocampus / Q000378:metabolism*; D008563:Membrane Lipids / Q000378:metabolism*; D015221:Potassium Channels / Q000378:metabolism*; D013569:Synapses / Q000378:metabolism*; D009435:Synaptic Transmission / Q000502:physiology*
chemical_list: D008563:Membrane Lipids; D015221:Potassium Channels