title: [Efficacy analysis of intermediate screws technique plus injectable calcium sulfate for thoracolumbar fracture in postmenopausal patients].
abstract: OBJECTIVE
  To explore the clinical efficacies of intermediate screws plus injectable calcium sulfate MIIGX3 for thoracolumbar fracture in postmenopausal patients.
  
  
  METHODS
  A total of 21 postmenopausal patients with vertebral compression fractures reconstructed with posterior internal fixation of intermediate screws technique and anterior vertebral augmentation of MIIGX3 technique in three dimension were retrospectively analyzed. The changes of fracture vertebral height and Cobb's angle were compared.Visual analogue scale (VAS) was performed to evaluate their symptoms. All patients were followed up.
  
  
  RESULTS
  Intermediate screws surgical technique plus MIIGX3 was successfully performed. The average injection dose was 4.6 ml.Leakage occurred intraoperatively in two cases. The average follow-up period was 15 (6-36) months. The VAS system demonstrated that pain decreased significantly (preoperative:7.8, postoperative:2.2). The height and Cobb's angle of fractured vertebra improved greatly. The preoperative values were 45.0 ± 6.4% and 19.4 ± 4.5° and postoperative ones 15.4 ± 3.9% and 8.64 ± 3.18° respectively. There was no occurrence of severe complications related with treatment.Except for 2 patients with a loss of 15% of vertebral height, the average heights of fractured vertebra in other 19 patients recovered to 85% of normal ones.
  
  
  CONCLUSIONS
  Thoracolumbar fracture in postmenopausal patients may be managed satisfactorily by intermediate screws and injectable calcium sulfate technique.Such a technique is both safe and effective. And its stable and durable reduction offers significant improvement.
authors.affiliation: Department of Spine Surgery, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Yu
authors.forename: Zhi-li
authors.initials: ZL
authors.lastname: Zeng
authors.forename: Shan-zhu
authors.initials: SZ
authors.lastname: Li
authors.forename: Yong-wei
authors.initials: YW
authors.lastname: Jia
authors.forename: Long
authors.initials: L
authors.lastname: Jia
authors.forename: Jian-jie
authors.initials: JJ
authors.lastname: Wang
authors.forename: Zhou-rui
authors.initials: ZR
authors.lastname: Wu
authors.forename: Xiao
authors.initials: X
authors.lastname: Hu
authors.forename: Wei
authors.initials: W
authors.lastname: Xu
authors.forename: Sujan
authors.initials: S
authors.lastname: Maharjan
authors.affiliation: Email: chlm.d@163.com.
authors.forename: Li-ming
authors.initials: LM
authors.lastname: Cheng
mesh_terms: D001863:Bone Screws; D002133:Calcium Sulfate / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D050815:Fractures, Compression / Q000601:surgery* / Q000628:therapy*; D006801:Humans; D008159:Lumbar Vertebrae / Q000293:injuries; D008875:Middle Aged; D017698:Postmenopause; D012189:Retrospective Studies; D016103:Spinal Fractures / Q000601:surgery* / Q000628:therapy*; D013904:Thoracic Vertebrae / Q000293:injuries; D016896:Treatment Outcome
chemical_list: D002133:Calcium Sulfate