title: Preclinical studies on comorbidity between depression and psychostimulant addiction.
abstract: Several clinical data indicate that depression is frequently comorbid with psychostimulant (cocaine, amphetamines) addiction. This short review summarizes preclinical results and observations showing how reward processes are modified in animal models of depression, and which depression-like effects are induced in experimental animals withdrawn from chronic treatment with psychostimulants.
authors.affiliation: Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, PL 31-343 Kraków, Poland. przegal@if-pan.krakow.pl.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Filip
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Frankowska
authors.forename: Joanna
authors.initials: J
authors.lastname: Jastrzębska
authors.forename: Karolina
authors.initials: K
authors.lastname: Wydra
authors.forename: Edmund
authors.initials: E
authors.lastname: Przegaliński
mesh_terms: D000818:Animals; D016739:Behavior, Addictive / Q000150:complications*; D000697:Central Nervous System Stimulants / Q000009:adverse effects*; D003863:Depression / Q000209:etiology*; D004353:Drug Evaluation, Preclinical; D006801:Humans
chemical_list: D000697:Central Nervous System Stimulants