title: Acute myeloid leukemia risk by industry and occupation.
abstract: Acute myeloid leukemia (AML) is the most common type of leukemia found in adults. Identifying jobs that pose a risk for AML may be useful for identifying new risk factors. A matched case-control analysis was conducted using California Cancer Registry data from 1988 to 2007. This study included 8999 cases of AML and 24 822 controls. Industries with a statistically significant increased AML risk were construction (matched odds ratio [mOR] = 1.13); crop production (mOR = 1.41); support activities for agriculture and forestry (mOR = 2.05); and animal slaughtering and processing (mOR = 2.09). Among occupations with a statistically significant increased AML risk were miscellaneous agricultural workers (mOR = 1.76); fishers and related fishing workers (mOR = 2.02); nursing, psychiatric and home health aides (mOR = 1.65); and janitors and building cleaners (mOR = 1.54). Further investigation is needed to confirm study findings and to identify specific exposures responsible for the increased risks.
authors.affiliation: Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention , Cincinnati, OH , USA.
authors.forename: Rebecca J
authors.initials: RJ
authors.lastname: Tsai
authors.forename: Sara E
authors.initials: SE
authors.lastname: Luckhaupt
authors.forename: Pam
authors.initials: P
authors.lastname: Schumacher
authors.forename: Rosemary D
authors.initials: RD
authors.lastname: Cress
authors.forename: Dennis M
authors.initials: DM
authors.lastname: Deapen
authors.forename: Geoffrey M
authors.initials: GM
authors.lastname: Calvert
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000383:Agriculture; D002140:California / Q000453:epidemiology; D016022:Case-Control Studies; D005260:Female; D005398:Fisheries; D016468:Forestry; D006801:Humans; D007221:Industry; D007951:Leukemia, Myeloid / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology*; D016272:Occupational Health / Q000706:statistics & numerical data; D009790:Occupations; D011159:Population Surveillance; D012042:Registries / Q000706:statistics & numerical data*; D018570:Risk Assessment / Q000379:methods / Q000706:statistics & numerical data*; D012307:Risk Factors; D055815:Young Adult
keywords: Acute myeloid leukemia; industry; occupation; risk factors