title: Human papillomavirus-associated diseases.
abstract: The human papillomavirus (HPV) may be associated with various oral, genital, and cutaneous conditions, both benign and malignant. The association between sexually transmitted α-HPV types is the strongest with cervical cancer because almost all such malignancies contain viral DNA, notably HPV types 16 and 18. The contribution of cancer causing HPV types in other anogenital, oral, and oropharyngeal malignancies, plus benign disorders, is lower and with a less significant public health concern. Cervical cytologic screening is a well-established preventive measure that allows early detection and successful treatment of precancerous cervical lesions. In cases of all other HPV-associated disorders, early detection of a precancerous lesion is either difficult or almost impossible. HPV vaccination remains the only preventive measure against most HPV-related diseases.
authors.affiliation: Department of Molecular Medicine, Rudjer Boskovic Institute, Bijenička 54, 10000 Zagreb, Croatia. Electronic address: grce@irb.hr.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Grce
authors.affiliation: Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Gundulićeva 5, 10000 Zagreb, Croatia.
authors.forename: Marinka
authors.initials: M
authors.lastname: Mravak-Stipetić
mesh_terms: D052685:Alphapapillomavirus / Q000145:classification*; D001005:Anus Neoplasms / Q000821:virology*; D052686:Betapapillomavirus / Q000145:classification*; D003218:Condylomata Acuminata / Q000517:prevention & control / Q000821:virology*; D005260:Female; D052689:Gammapapillomavirus / Q000145:classification*; D005833:Genital Neoplasms, Female / Q000517:prevention & control / Q000821:virology*; D000068857:Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; D006801:Humans; D007822:Laryngeal Neoplasms / Q000821:virology; D008297:Male; D009059:Mouth Diseases / Q000821:virology; D010212:Papilloma / Q000821:virology; D053918:Papillomavirus Vaccines; D010412:Penile Neoplasms / Q000821:virology*; D018570:Risk Assessment
chemical_list: D000068857:Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; D053918:Papillomavirus Vaccines; C510352:human papillomavirus vaccine, L1 type 16, 18