title: Antimicrobial activities of various fractions of longan (Dimocarpus longan Lour. Fen Ke) seed extract.
abstract: The antimicrobial activities of longan (Dimocarpus longan Lour. Fen ke) seed extracts were investigated using a disc diffusion method and also determining the minimal inhibitory concentration. The DL-P01-SI01 fraction showed that the strongest activity against Staphylococcus aureus and methicillin-resistant S. aureus at MIC 64 μg/mL, which was found to be due to the phenolic compounds. The HPLC analysis showed that the major phenolic compounds are gallic acid, corilagin, ethyl gallate and ellagic acid.
authors.affiliation: Laboratory of Antrodia Certification Center, Joben Bio-medical Co, Ltd. , Pingtung , Taiwan and.
authors.forename: Huang-Chung
authors.initials: HC
authors.lastname: Tseng
authors.forename: Wan-Ting
authors.initials: WT
authors.lastname: Wu
authors.forename: Ho-Shin
authors.initials: HS
authors.lastname: Huang
authors.forename: Ming-Chang
authors.initials: MC
authors.lastname: Wu
mesh_terms: D040981:Acinetobacter baumannii / Q000187:drug effects; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D002851:Chromatography, High Pressure Liquid; D004610:Ellagic Acid / Q000494:pharmacology; D005707:Gallic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D005960:Glucosides / Q000494:pharmacology; D006801:Humans; D047348:Hydrolyzable Tannins; D015603:Keratinocytes / Q000166:cytology / Q000187:drug effects; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010636:Phenols / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology*; D011425:Propionibacterium acnes / Q000187:drug effects; D012475:Salmonella / Q000187:drug effects; D029631:Sapindaceae / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects; D013295:Streptococcus mutans / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D005960:Glucosides; D047348:Hydrolyzable Tannins; D010636:Phenols; D010936:Plant Extracts; D004610:Ellagic Acid; C048734:ethyl gallate; C049096:corilagin; D005707:Gallic Acid
keywords: Antimicrobial activity; corilagin; ellagic acid; ethyl gallate; longan seed