title: SOAPdenovo-Trans: de novo transcriptome assembly with short RNA-Seq reads.
abstract: BACKGROUND
  Transcriptome sequencing has long been the favored method for quickly and inexpensively obtaining a large number of gene sequences from an organism with no reference genome. Owing to the rapid increase in throughputs and decrease in costs of next- generation sequencing, RNA-Seq in particular has become the method of choice. However, the very short reads (e.g. 2 × 90 bp paired ends) from next generation sequencing makes de novo assembly to recover complete or full-length transcript sequences an algorithmic challenge.
  
  
  RESULTS
  Here, we present SOAPdenovo-Trans, a de novo transcriptome assembler designed specifically for RNA-Seq. We evaluated its performance on transcriptome datasets from rice and mouse. Using as our benchmarks the known transcripts from these well-annotated genomes (sequenced a decade ago), we assessed how SOAPdenovo-Trans and two other popular transcriptome assemblers handled such practical issues as alternative splicing and variable expression levels. Our conclusion is that SOAPdenovo-Trans provides higher contiguity, lower redundancy and faster execution.
  
  
  METHODS
  Source code and user manual are available at http://sourceforge.net/projects/soapdenovotrans/.
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi ArabiaSchool of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawha
authors.forename: Yinlong
authors.initials: Y
authors.lastname: Xie
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
authors.forename: Gengxiong
authors.initials: G
authors.lastname: Wu
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi ArabiaSchool of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawha
authors.forename: Jingbo
authors.initials: J
authors.lastname: Tang
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi ArabiaSchool of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawha
authors.forename: Ruibang
authors.initials: R
authors.lastname: Luo
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
authors.forename: Jordan
authors.initials: J
authors.lastname: Patterson
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
authors.forename: Shanlin
authors.initials: S
authors.lastname: Liu
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
authors.forename: Weihua
authors.initials: W
authors.lastname: Huang
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
authors.forename: Guangzhu
authors.initials: G
authors.lastname: He
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi ArabiaSchool of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawha
authors.forename: Shengchang
authors.initials: S
authors.lastname: Gu
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
authors.forename: Shengkang
authors.initials: S
authors.lastname: Li
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
authors.forename: Xin
authors.initials: X
authors.lastname: Zhou
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
authors.forename: Tak-Wah
authors.initials: TW
authors.lastname: Lam
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
authors.forename: Yingrui
authors.initials: Y
authors.lastname: Li
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
authors.forename: Xun
authors.initials: X
authors.lastname: Xu
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi ArabiaSchool of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawha
authors.forename: Gane Ka-Shu
authors.initials: GK
authors.lastname: Wong
authors.affiliation: School of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi ArabiaSchool of Bioscience and Bioengineering, South China University of Technology 510006, Guangzhou, China, BGI-Shenzhen, Shenzhen 518083, China, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory and Department of Computer Science, University of Hong Kong, Pokfulam, Hong Kong, Institute of Biomedical Engineering, XiangYa School of Medicine, Central South University, Changsha 410008, China, BGI-tech, BGI-Shenzhen, Shenzhen 518083, China, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK-2200, Denmark, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark and Princess Al Jawha
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
mesh_terms: D000465:Algorithms; D017398:Alternative Splicing; D000818:Animals; D020869:Gene Expression Profiling / Q000379:methods*; D023281:Genomics / Q000379:methods; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D051379:Mice; D012275:Oryza / Q000235:genetics; D017423:Sequence Analysis, RNA / Q000379:methods*