title: Impact of gender on COPD expression in a real-life cohort.
abstract: Reports regarding gender-related differences in COPD expression have provided conflicting results. In the French Initiatives BPCO real-world cohort, which contained 688 patients (146 women) when data were extracted, women were matched with men (1:3 ratio: n = 107:275) on age (5-year intervals) and FEV1 (5% predicted intervals) and comparisons were performed using univariate logistic regressions. For a given age and level of airflow obstruction, women with COPD had higher BOD scores due to more pronounced dyspnea and lower BMI, suggesting worse prognosis, and were more likely to exhibit anxiety, suggesting the need for specific assessment and care.
authors.affiliation: Service de Pneumologie et Soins Intensifs Respiratoires, Groupe Hospitalier Cochin Broca Hôtel-Dieu, AP-HP and Université Paris Descartes, Sorbonne Paris Cité, Paris, France. nicolas.roche@cch.aphp.fr.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Roche
authors.forename: Gaetan
authors.initials: G
authors.lastname: Deslée
authors.forename: Denis
authors.initials: D
authors.lastname: Caillaud
authors.forename: Graziella
authors.initials: G
authors.lastname: Brinchault
authors.forename: Isabelle
authors.initials: I
authors.lastname: Court-Fortune
authors.forename: Pascale
authors.initials: P
authors.lastname: Nesme-Meyer
authors.forename: Pascale
authors.initials: P
authors.lastname: Surpas
authors.forename: Roger
authors.initials: R
authors.lastname: Escamilla
authors.forename: Thierry
authors.initials: T
authors.lastname: Perez
authors.forename: Pascal
authors.initials: P
authors.lastname: Chanez
authors.forename: Christophe
authors.initials: C
authors.lastname: Pinet
authors.forename: Gilles
authors.initials: G
authors.lastname: Jebrak
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Paillasseur
authors.forename: Pierre-Régis
authors.initials: PR
authors.lastname: Burgel
mesh_terms: D000368:Aged; D015992:Body Mass Index; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology*; D012727:Sex Characteristics