title: [Study on antitumor effect of wutousan].
abstract: OBJECTIVE
  To screen the active extracts from three traditional Chinese medicines.
  
  
  METHODS
  Five traditional Chinese medicines including Unprocessed Aconiti Radix, Aconiti Radix Cocta, Phellodendri Chinensis Cortex were extracted with 70% alcohol or water respectively. The cell proliferation effect of these extracts was tested with MTT assay in SMMC7721, MCF7, A549, Hela and SGC7901.
  
  
  RESULTS
  The 70% alcohol extract of Unprocessed Aconiti Radix, Aconiti Radix Cocta, Phellodendri Chinensis Cortex displayed remarkable inhibitory effect in the A549 and Hela in a dose-dependent manner.
  
  
  CONCLUSIONS
  The alcohol extract of Unprocessed Aconiti Radix, Aconiti Radix Cocta, Phellodendri Chinensis Cortex and the water extraction of Phellodendri Chinensis Cortex present obviously inhibitory effect in both A549 and Hela. The combination of Aconiti Radix with Phellodendri Chinensis Cortex has synergistic inhibitory effect on Hela.
authors.affiliation: School of Medicine, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zheng
authors.affiliation: School of Medicine, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Gu-Milan
authors.initials: GM
authors.lastname: Sidike
authors.affiliation: School of Medicine, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Yan-Min
authors.initials: YM
authors.lastname: Zhang
mesh_terms: D031841:Aconitum / Q000737:chemistry*; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D008516:Medicine, Chinese Traditional
chemical_list: D000970:Antineoplastic Agents; D004365:Drugs, Chinese Herbal