title: A new aromatic glycoside from Glehnia littoralis.
abstract: A new aromatic glycoside (1) was isolated from the roots of Glehnia littoralis Fr. Schmidtex Miq. Its structure was elucidated as vanillic acid 1-O-[β-D-apiofuranosyl-(1 → 6)-β-D-glucopyranoside] ester mainly by analysing the NMR and MS spectral data. In the in vitro assays, compound 1 displayed some TNF-α secretion inhibitory activity.
authors.affiliation: a Department of Biochemistry and Molecular Biology , College of Basic Medical Sciences, Second Military Medical University , Xiangyin Road 800, Shanghai , P.R. China.
authors.forename: Zi-Jin
authors.initials: ZJ
authors.lastname: Feng
authors.forename: Xiao-Hong
authors.initials: XH
authors.lastname: Zhang
authors.forename: Jian-Peng
authors.initials: JP
authors.lastname: Zhang
authors.forename: Xiao-Hui
authors.initials: XH
authors.lastname: Shang
authors.forename: Yun
authors.initials: Y
authors.lastname: Gao
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Lu
authors.forename: Xiao-Yu
authors.initials: XY
authors.lastname: Liu
authors.forename: Bing-Hua
authors.initials: BH
authors.lastname: Jiao
mesh_terms: D019661:Apiaceae / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors / Q000378:metabolism; D014641:Vanillic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D004365:Drugs, Chinese Herbal; D006027:Glycosides; D014409:Tumor Necrosis Factor-alpha; C000591582:vanillic acid 1-O-(beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside) ester; D014641:Vanillic Acid