title: [Asbestos cement factory in Broni (Pavia, Italy): a mortality study].
abstract: BACKGROUND
  To date, no study has reported cause-specific Standardized Mortality Ratios (SMR) for asbestos-cement workers at a manufacturing establishment in Broni (Pavia, Italy). This site is among those specifically targeted by Italian Law for reclamation (SIN - Site of National Interest for remediation).
  
  
  OBJECTIVE
  To provide cause-specific SMRs for asbestos-cement workers in the Broni (Pavia, Italy) factory, with particular regard to duration of employment and latency.
  
  
  METHODS
  Cause-specific SMRs for asbestos-cement workers (1296 workers hired since 1/1/1950 and with follow-up period 1/1/1970-30/06/2004: 1254 males and 42 females, 545 deaths, 523 males and 22 females) were calculated using the cause-specific mortality rates for the Lombardy Region. Similarly, for pleural and peritoneal mesothelioma and lung cancer among male workers, SMRs by duration of employment and latency were calculated.
  
  
  RESULTS
  Significantly increased SMRs were observed among male workers for pleural (SMR 17.99, 95% CI 11.75-26.36) and peritoneal (SMR 10.10, 95% CI 4.05-20.77) mesothelioma and lung cancer (SMR 1.26, 95% CI 1.02-1.55) and among female workers for pleural mesothelioma (SMR 68.90, 95% CI 8.33-248.90) and ovarian cancer (SMR 8.56, 95% CI 1.04-30.91). Only among male workers, was a significant risk trend observed for pleural mesothelioma by duration of employment and for lung cancer by latency. Significantly reduced SMRs were observed, among male workers for all causes of death, cardiovascular and respiratory diseases.
  
  
  CONCLUSIONS
  The results of this cohort study showed increased SMRs for pleural and peritoneal mesothelioma and lung cancer among male workers and for pleural mesothelioma and ovarian cancer among female workers. These results are consistent with the literature data.
authors.affiliation: Dipartimento di Sanità Pubblica, Medicina Sperimentale e Forense, Sezione di Medicina del Lavoro "Salvatore Maugeri, Università degli Studi di Pavia. enrico.oddone@unipv.it
authors.forename: E
authors.initials: E
authors.lastname: Oddone
authors.affiliation: Unità di Statistica Medica ed Epidemiologia, Dipartimento di Medicina Traslazionale, Università degli Studi del Piemonte Orientale e CPO Piemonte, Novara.
authors.forename: Daniela
authors.initials: D
authors.lastname: Ferrante
authors.affiliation: Unità di Statistica Medica ed Epidemiologia, Dipartimento di Medicina Traslazionale, Università degli Studi del Piemonte Orientale e CPO Piemonte, Novara.
authors.forename: Tiziana
authors.initials: T
authors.lastname: Cena
authors.affiliation: Unità di Statistica Medica ed Epidemiologia, Dipartimento di Medicina Traslazionale, Università degli Studi del Piemonte Orientale e CPO Piemonte, Novara.
authors.forename: Sara
authors.initials: S
authors.lastname: Tùnesi
authors.affiliation: Centro Diagnostico Italiano, Milano.
authors.forename: P
authors.initials: P
authors.lastname: Amendola
authors.affiliation: Centro Diagnostico Italiano, Milano.
authors.forename: C
authors.initials: C
authors.lastname: Magnani
mesh_terms: D000328:Adult; D001194:Asbestos / Q000009:adverse effects*; D002423:Cause of Death; D015331:Cohort Studies; D003252:Construction Materials / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008654:Mesothelioma / Q000401:mortality*; D008875:Middle Aged; D009784:Occupational Diseases / Q000401:mortality*; D055815:Young Adult
chemical_list: D001194:Asbestos
vernacular_title: Studio di mortalità in una fabbrica per la produzione di manufatti in cemento-amianto in provincia di Pavia.