title: Comparison of clinical and perinatal outcomes in early- and late-onset preeclampsia.
abstract: OBJECTIVE
  To compare the clinical and laboratory findings and maternal-perinatal outcomes between women with early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE).
  
  
  METHODS
  One hundred and fifty-four women with preeclampsia (PE) who delivered in our clinic were included in the study. Perinatal and obstetric outcomes were evaluated.
  
  
  RESULTS
  The incidence of abnormal uterine artery (UtA) velocity waveform was significantly higher in the EO-PE group (71.4 vs 30.1 %) (p < 0.001). The incidences of small-for-gestational age, oligohydramnios, Apgar score <7 at 5 min, stillbirth and early neonatal death rates were significantly higher in women with EO-PE compared to LO-PE (p < 0.01). Maternal complications were only recorded in women with severe PE.
  
  
  CONCLUSIONS
  EO-PE, especially with abnormal UtA Doppler findings defines a placentation abnormality with higher perinatal adverse outcomes.
authors.affiliation: Cerrahpasa Tip Fakultesi, Kadin Hastaliklari ve Dogum Anabilim Dali, Istanbul Universitesi, Kocamustafapasa, 34750, Istanbul, Turkey, madazli@superonline.com.
authors.forename: Riza
authors.initials: R
authors.lastname: Madazli
authors.forename: Mehmet Aytaç
authors.initials: MA
authors.lastname: Yuksel
authors.forename: Metehan
authors.initials: M
authors.lastname: Imamoglu
authors.forename: Abdullah
authors.initials: A
authors.lastname: Tuten
authors.forename: Mahmut
authors.initials: M
authors.lastname: Oncul
authors.forename: Burcu
authors.initials: B
authors.lastname: Aydin
authors.forename: Gokhan
authors.initials: G
authors.lastname: Demirayak
mesh_terms: D000328:Adult; D001034:Apgar Score; D005260:Female; D005333:Fetus / Q000098:blood supply; D005865:Gestational Age; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D016104:Oligohydramnios / Q000453:epidemiology; D021041:Placental Circulation / Q000502:physiology; D010929:Placentation / Q000502:physiology; D011225:Pre-Eclampsia / Q000000981:diagnostic imaging* / Q000453:epidemiology* / Q000209:etiology; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D050497:Stillbirth / Q000453:epidemiology; D013997:Time Factors; D018615:Ultrasonography, Doppler, Color; D055988:Uterine Artery / Q000000981:diagnostic imaging*; D014599:Uterus / Q000098:blood supply*