title: Vaccine effectiveness in preventing laboratory-confirmed influenza in Navarre, Spain: 2013/14 mid-season analysis.
abstract: We estimate mid-2013/14 season vaccine effectiveness (VE) of the influenza trivalent vaccine in Navarre, Spain. Influenza-like illness cases attended in hospital (n=431) and primary healthcare (n=344) were included. The overall adjusted VE in preventing laboratory-confirmed influenza was 24% (95% CI: -14 to 50). The VE was 40% (95% CI: -12 to 68) against influenza A(H1)pdm09 and 13% (95% CI: -36 to 45) against influenza A(H3). These results suggest a moderate preventive effect against influenza A(H1)pdm09 and low protection against influenza A(H3).
authors.affiliation: Instituto de Salud Publica de Navarra (Public Health Institute of Navarre), Pamplona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Castilla
authors.forename: I
authors.initials: I
authors.lastname: Martínez-Baz
authors.forename: A
authors.initials: A
authors.lastname: Navascués
authors.forename: M
authors.initials: M
authors.lastname: Fernandez-Alonso
authors.forename: G
authors.initials: G
authors.lastname: Reina
authors.forename: M
authors.initials: M
authors.lastname: Guevara
authors.forename: J
authors.initials: J
authors.lastname: Chamorro
authors.forename: M T
authors.initials: MT
authors.lastname: Ortega
authors.forename: E
authors.initials: E
authors.lastname: Albéniz
authors.forename: F
authors.initials: F
authors.lastname: Pozo
authors.forename: C
authors.initials: C
authors.lastname: Ezpeleta
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000517:prevention & control*; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology*; D007252:Influenza Vaccines / Q000276:immunology* / Q000627:therapeutic use; D007251:Influenza, Human / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control* / Q000821:virology; D007753:Laboratories; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011320:Primary Health Care; D012621:Seasons; D018571:Sentinel Surveillance; D013030:Spain / Q000453:epidemiology; D016896:Treatment Outcome; D014611:Vaccination / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D007252:Influenza Vaccines