title: Toll-like receptor-4 signaling: a new potential therapeutic pathway for rheumatoid arthritis.
abstract: The Toll-like receptor-4 signaling (TLR-4) has been found to be over-expressed in rheumatoid arthritis (RA) synovium. Furthermore, it regulates the expression of pro-inflammatory cytokines. Based on the current evidences, TLR-4 may be a new potential therapeutic pathway for RA.
authors.affiliation: School of Pharmacy, Anhui Medical University, Mei Shan Road, Hefei, 230032, Anhui Province, China.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Li
authors.forename: Tao
authors.initials: T
authors.lastname: Xu
authors.forename: Yarui
authors.initials: Y
authors.lastname: Wang
authors.forename: Cheng
authors.initials: C
authors.lastname: Huang
authors.forename: Jun
authors.initials: J
authors.lastname: Li
mesh_terms: D001172:Arthritis, Rheumatoid / Q000235:genetics*; D044466:Asian People; D005260:Female; D006801:Humans; D008297:Male; D020641:Polymorphism, Single Nucleotide; D051197:Toll-Like Receptor 4 / Q000235:genetics*
chemical_list: D051197:Toll-Like Receptor 4