title: Modelling of impulsional pH variations using ChemFET-based microdevices: application to hydrogen peroxide detection.
abstract: This work presents the modelling of impulsional pH variations in microvolume related to water-based electrolysis and hydrogen peroxide electrochemical oxidation using an Electrochemical Field Effect Transistor (ElecFET) microdevice. This ElecFET device consists of a pH-Chemical FET (pH-ChemFET) with an integrated microelectrode around the dielectric gate area in order to trigger electrochemical reactions. Combining oxidation/reduction reactions on the microelectrode, water self-ionization and diffusion properties of associated chemical species, the model shows that the sensor response depends on the main influential parameters such as: (i) polarization parameters on the microelectrode, i.e., voltage (Vp) and time (t(p)); (ii) distance between the gate sensitive area and the microelectrode (d); and (iii) hydrogen peroxide concentration ([H2O2]). The model developed can predict the ElecFET response behaviour and creates new opportunities for H2O2-based enzymatic detection of biomolecules.
authors.affiliation: CNRS, LAAS, 7 avenue du colonel Roche, F-31400 Toulouse, France. dialloabdoukarim@yahoo.fr.
authors.forename: Abdou Karim
authors.initials: AK
authors.lastname: Diallo
authors.affiliation: CNRS, LAAS, 7 avenue du colonel Roche, F-31400 Toulouse, France. ldjeghla@laas.fr.
authors.forename: Lyes
authors.initials: L
authors.lastname: Djeghlaf
authors.affiliation: CNRS, LAAS, 7 avenue du colonel Roche, F-31400 Toulouse, France. jlaunay@laas.fr.
authors.forename: Jerome
authors.initials: J
authors.lastname: Launay
authors.affiliation: CNRS, LAAS, 7 avenue du colonel Roche, F-31400 Toulouse, France. temple@laas.fr.
authors.forename: Pierre
authors.initials: P
authors.lastname: Temple-Boyer
mesh_terms: D004572:Electrolysis; D006861:Hydrogen Peroxide / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D008839:Microelectrodes; D010084:Oxidation-Reduction; D014173:Transistors, Electronic
chemical_list: D006861:Hydrogen Peroxide