title: Risk factors and the prevention of oral clefts.
abstract: This article presents general aspects of risk factors and particularities of the management of individuals with oral clefts (OCs). A practical manual of prevention and management of this congenital defect was prepared based on a review of the literature and using data from Brazilian multicenter studies. Since OCs require efforts from all levels of healthcare, the data herein presented permits appropriate follow-up for affected individuals and their families. Also, the recognition of risk factors is crucial for planning and implementing preventive measures at the individual and population levels.
authors.affiliation: Department of Medical Genetics, Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil.
authors.forename: Vera Lucia
authors.initials: VL
authors.lastname: Gil-da-Silva-Lopes
authors.affiliation: Faculty of Medicine, Federal University of Alagoas, Maceio, AL, Brazil.
authors.forename: Isabella Lopes
authors.initials: IL
authors.lastname: Monlleo
mesh_terms: D001938:Brazil; D002971:Cleft Lip / Q000209:etiology* / Q000517:prevention & control*; D002972:Cleft Palate / Q000209:etiology* / Q000517:prevention & control*; D006801:Humans; D012307:Risk Factors