title: Low-intensity pulsed ultrasound therapy stimulates callus formation between host femur and cortical onlay strut allograft.
abstract: Cortical onlay strut allografting is a promising surgical option to reconstruct and reinforce the deficient femur in a hip arthroplasty. However, the union of the allograft to the host bone takes a long time. To accelerate the process of cortical onlay strut allograft healing, we studied the effects of low-intensity pulsed ultrasound (LIPUS) on callus formation. From 2 wk after the operation, LIPUS was given for 20 min/d at each end of the strut allograft. The LIPUS treatment group was assigned 14 allograft transplantations, while 21 control patients were treated without LIPUS. The LIPUS treatment group formed calluses and had complete bridging between the host femur and the allograft faster after operation (16.9 and 29.4 wk after operation, respectively) compared with the control group (40.7 and 82.0 wk after operation, respectively). Our findings showed that LIPUS stimulated bone bonding between the host femur and the cortical onlay strut allografts.
authors.affiliation: Department of Orthopaedics, Kyoto University, Kyoto, Kyoto, Japan. Electronic address: hakiyama@kuhp.kyoto-u.ac.jp.
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Akiyama
authors.affiliation: Hachiya Orthopedics, Nagoya, Aichi, Japan.
authors.forename: Yudo
authors.initials: Y
authors.lastname: Hachiya
authors.affiliation: Department of Orthopaedic Surgery, Aichi Medical University, Nagakute, Aichi, Japan.
authors.forename: Hiromi
authors.initials: H
authors.lastname: Otsuka
authors.affiliation: Department of Orthopaedic Surgery, Aichi Medical University, Nagakute, Aichi, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Kurisuno
authors.affiliation: Department of Orthopaedics, Kyoto University, Kyoto, Kyoto, Japan; Department of Orthopaedic Surgery, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Kawanabe
authors.affiliation: Department of Orthopedic Surgery, Hokkaido Orthopedic Memorial Hospital, Sapporo, Japan.
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Katayama
authors.affiliation: Department of Orthopedic Surgery, Hokkaido Orthopedic Memorial Hospital, Sapporo, Japan.
authors.forename: Hisanori
authors.initials: H
authors.lastname: Ohura
authors.affiliation: Department of Orthopaedics, Kyoto University, Kyoto, Kyoto, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Yamamoto
authors.affiliation: Department of Orthopaedic Surgery, Aichi Medical University, Nagakute, Aichi, Japan.
authors.forename: Keiji
authors.initials: K
authors.lastname: Sato
authors.affiliation: Department of Orthopaedics, Kyoto University, Kyoto, Kyoto, Japan.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Matsuda
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D064591:Allografts; D019644:Arthroplasty, Replacement, Hip; D002146:Bony Callus; D005260:Female; D005269:Femur / Q000637:transplantation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013977:Tibia / Q000637:transplantation*; D014464:Ultrasonic Therapy; D014945:Wound Healing
keywords: Bone; Femur; Hip arthroplasty; Strut bone allograft; Ultrasound stimulation