title: MDCT imaging of Alloderm biologic mesh spacers in the abdomen and pelvis--preliminary experience.
abstract: The purpose of this study was to assess the attenuation characteristics of the Alloderm Biologic Mesh Spacer (ABMS) in the abdomen and pelvis. Of nine patients with ABMS, five underwent multidetector computed tomographic scans at 1, 4, and 7 months postsurgery. Two patients underwent positron emission tomography-computed tomography (PET-CT). The pre- and postcontrast images were evaluated for attenuation characteristics of ABMS. The PET-CT scans were reviewed for [18F]-fluorodeoxyglucose (FDG) uptake. We observed increase in the attenuation characteristics of the spacers on follow-up imaging (P<.05). No FDG uptake was noted on PET-CT. To conclude, ABMS demonstrates soft tissue attenuation on noncontrast CT and shows increase attenuation on serial CT scans.
authors.affiliation: Department of Abdominal Imaging and Intervention, Massachusetts General Hospital 55 Fruit St, Boston, 02114 MA, USA. Electronic address: Hedgire.Sandeep@mgh.harvard.edu.
authors.forename: Sandeep S
authors.initials: SS
authors.lastname: Hedgire
authors.affiliation: Department of Abdominal Imaging and Intervention, Massachusetts General Hospital 55 Fruit St, Boston, 02114 MA, USA.
authors.forename: Azadeh
authors.initials: A
authors.lastname: Elmi
authors.affiliation: Department of Abdominal Imaging and Intervention, Massachusetts General Hospital 55 Fruit St, Boston, 02114 MA, USA.
authors.forename: Avinash R
authors.initials: AR
authors.lastname: Kambadakone
authors.affiliation: Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065.
authors.forename: Sam
authors.initials: S
authors.lastname: Yoon
authors.affiliation: Department of Abdominal Imaging and Intervention, Massachusetts General Hospital 55 Fruit St, Boston, 02114 MA, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Blake
authors.affiliation: Department of Abdominal Imaging and Intervention, Massachusetts General Hospital 55 Fruit St, Boston, 02114 MA, USA.
authors.forename: Mukesh G
authors.initials: MG
authors.lastname: Harisinghani
mesh_terms: D000005:Abdomen; D062088:Acellular Dermis; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003094:Collagen; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography / Q000379:methods*; D010388:Pelvis; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D013526:Surgical Mesh
chemical_list: C440568:Alloderm; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D003094:Collagen
keywords: Alloderm; Biologic mesh spacers; External beam radiation; MDCT; Oncosurgery; Soft tissue attenuation