title: [Advance in studies on anti-infection of andrographolide and its derivatives in past 10 years].
abstract: Andrographolide (AG) is a main effective ingredient in leaves of Andrographis paniculata. AG and its derivatives have such effects in anti-infection, anti-tumor and immuno-regulation. Particularly, its antibacterial, antiviral and anti-protozoal activities play an increasingly important role in resisting opportunistic infections. On the basis of our studies on AG over the years, we made a summary for the basis and clinical studies on AG and its derivatives over the past 10 years.
authors.affiliation: School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei 230038, China. 1136510704@qq.com
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Yan
authors.affiliation: School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei 230038, China.
authors.forename: Gao-Xiang
authors.initials: GX
authors.lastname: Shi
authors.affiliation: School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei 230038, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Shao
authors.affiliation: School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei 230038, China.
authors.forename: Tian-Ming
authors.initials: TM
authors.lastname: Wang
authors.affiliation: School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei 230038, China.
authors.forename: Chang-Zhong
authors.initials: CZ
authors.lastname: Wang
mesh_terms: D035685:Andrographis / Q000737:chemistry*; D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D004224:Diterpenes / Q000737:chemistry / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D013329:Structure-Activity Relationship
chemical_list: D000890:Anti-Infective Agents; D004224:Diterpenes; D004365:Drugs, Chinese Herbal; C030419:andrographolide