title: Arsenic speciation in total contents and bioaccessible fractions in atmospheric particles related to human intakes.
abstract: Speciation of inorganic trivalent arsenicals (iAs(III)), inorganic pentavalent arsenicals (iAs(V)), monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) in total arsenic (As) content and its bioaccessible fractions contained in road dust, household air-conditioning (AC) filter dust and PM2.5 was investigated. Inorganic As, especially iAs(V), was observed as the dominant species. Physiologically based extraction test (PBET), an in-vitro gastrointestinal method, was used to estimate the oral As bioaccessibility in coarse particles and the species present in the oral bioaccessible fraction. A composite lung simulating serum was used to mimic the pulmonary condition to extract the respiratory bioaccessible As and its species in PM2.5. Reduction of iAs(V) to iAs(III) occurred in both in-vitro gastrointestinal and lung simulating extraction models. The inorganic As species was the exclusive species for absorption through ingestion and inhalation of atmospheric particles, which was an important exposure route to inorganic As, in addition to drinking water and food consumption.
authors.affiliation: Faculty of Environmental Science and Engineering, Sun Yat-sen University, Guangzhou 510275, PR China; State Key Laboratory in Marine Pollution - Croucher Institute for Environmental Sciences, Hong Kong Baptist University and City University of Hong Kong, Hong Kong, China.
authors.forename: Minjuan
authors.initials: M
authors.lastname: Huang
authors.affiliation: State Key Laboratory in Marine Pollution - Croucher Institute for Environmental Sciences, Hong Kong Baptist University and City University of Hong Kong, Hong Kong, China.
authors.forename: Xunwen
authors.initials: X
authors.lastname: Chen
authors.affiliation: State Key Laboratory in Marine Pollution - Croucher Institute for Environmental Sciences, Hong Kong Baptist University and City University of Hong Kong, Hong Kong, China.
authors.forename: Yinge
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Faculty of Environmental Science and Engineering, Sun Yat-sen University, Guangzhou 510275, PR China.
authors.forename: Chuen
authors.initials: C
authors.lastname: Yu Chan
authors.affiliation: State Key Laboratory in Marine Pollution - Croucher Institute for Environmental Sciences, Hong Kong Baptist University and City University of Hong Kong, Hong Kong, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.affiliation: Faculty of Environmental Science and Engineering, Sun Yat-sen University, Guangzhou 510275, PR China.
authors.forename: Xuemei
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Science and Environmental Studies, The Hong Kong Institute of Education, Tai Po, Hong Kong, China; State Key Laboratory in Marine Pollution - Croucher Institute for Environmental Sciences, Hong Kong Baptist University and City University of Hong Kong, Hong Kong, China. Electronic address: mhwong@hkbu.edu.hk.
authors.forename: Ming Hung
authors.initials: MH
authors.lastname: Wong
mesh_terms: D000393:Air Pollutants / Q000032:analysis*; D001151:Arsenic / Q000032:analysis*; D001272:Atmosphere / Q000737:chemistry*; D004781:Environmental Exposure / Q000032:analysis* / Q000706:statistics & numerical data; D006801:Humans
chemical_list: D000393:Air Pollutants; D001151:Arsenic
keywords: As speciation; Bioaccessibility; Daily intakes of inorganic As; HPLC–ICP-MS