title: Case report: First confirmed case of canine peritoneal larval cestodiasis caused by Mesocestoides vogae (syn. M. corti) in Japan.
abstract: Canine peritoneal larval cestodiasis (CPLC) is an unusual parasitic disease in dogs that is caused by asexual proliferation of larval Mesocestoides. A 12 year-old spayed Shetland sheepdog with abdominal distension was referred to the Animal Medical Center at Nihon University, Japan. The presence of ascites was confirmed by abdominal ultrasonography and X-ray imaging. In addition, a number of parasites were observed in the ascitic fluid collected by abdominal paracentesis. Each of the whitish colored parasites was less than 1mm in size. The parasites were morphologically identified as Mesocestoides sp. tetrathyridia. The parasites had four suckers and calcareous corpuscles, but no hooks or rostellum. Mitochondrial (mt) 12S rDNA and mt cytochrome c oxidase subunit 1 DNA amplified from the tetrathyridia were used for molecular identification to species level. DNA sequence analysis showed that the tetrathyridia shared more than 99% identity with M. vogae (syn. M. corti) for each gene. The patient was treated with a standard dose (5mg/kg) of praziquantel, which was administered subcutaneously twice at an interval of 14 days. This resulted in successful deworming. This is the first case that CPLC was diagnosed in a dog that had never been taken outside of Japan, indicating that M. vogae is distributed in this country.
authors.affiliation: Laboratory of Medical Zoology, Department of Veterinary Medicine, Faculty of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Kashiide
authors.affiliation: Laboratory of Medical Zoology, Department of Veterinary Medicine, Faculty of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan. Electronic address: matsumoto.jun82@nihon-u.ac.jp.
authors.forename: Jun
authors.initials: J
authors.lastname: Matsumoto
authors.affiliation: Laboratory of Comprehensive Veterinary Clinical Studies, Department of Veterinary Medicine, Faculty of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Yamaya
authors.affiliation: Laboratory of Medical Zoology, Department of Veterinary Medicine, Faculty of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.
authors.forename: Aya
authors.initials: A
authors.lastname: Uwasawa
authors.affiliation: Laboratory of Comprehensive Veterinary Clinical Studies, Department of Veterinary Medicine, Faculty of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.
authors.forename: Ai
authors.initials: A
authors.lastname: Miyoshi
authors.affiliation: Yamada Animal Hospital, Asahi-ku, Yokohama, Kanagawa 241-0822, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Yamada
authors.affiliation: Laboratory of Comprehensive Veterinary Clinical Studies, Department of Veterinary Medicine, Faculty of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Watari
authors.affiliation: Laboratory of Medical Zoology, Department of Veterinary Medicine, Faculty of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.
authors.forename: Sadao
authors.initials: S
authors.lastname: Nogami
mesh_terms: D000818:Animals; D002590:Cestode Infections / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology*; D004285:Dogs; D003576:Electron Transport Complex IV / Q000235:genetics; D005260:Female; D007564:Japan; D007814:Larva; D008645:Mesocestoides / Q000235:genetics / Q000502:physiology*; D010537:Peritoneum / Q000469:parasitology*; D011223:Praziquantel / Q000627:therapeutic use; D012335:RNA, Ribosomal / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid; D016896:Treatment Outcome
chemical_list: D012335:RNA, Ribosomal; C075526:RNA, ribosomal, 12S; D011223:Praziquantel; D003576:Electron Transport Complex IV
keywords: Canine peritoneal larval cestodiasis (CPLC); Mesocestoides vogae (syn. M. corti); Tetrathyridium