title: Prevention of venous thromboembolism, 2nd edition: Korean Society of Thrombosis and Hemostasis Evidence-based Clinical Practice Guidelines.
abstract: In 2010, we proposed the first Korean Guidelines for the Prevention of Venous Thromboembolism (VTE). It was applicable to Korean patients, by modifying the contents of the second edition of the Japanese guidelines for the prevention of VTE and the 8th edition of the American College of Chest Physicians (ACCP) evidence-based clinical practice guidelines. From 2007 to 2011, we conducted a nationwide study regarding the incidence of VTE after major surgery using the Health Insurance Review and Assessment Service (HIRA) database. In addition, we have considered the 9th edition of the ACCP Evidenced-Based Clinical Practice Guidelines, published in 2012. It emphasized the importance of clinically relevant events as opposed to asymptomatic outcomes with preferences for both thrombotic and bleeding outcomes. Thus, in the development of the new Korean guidelines, three major points were addressed: 1) the new guidelines stratify patients into 4 risk groups (very low, low, moderate, and high) according to the actual incidence of symptomatic VTE from the HIRA databases; 2) the recommended optimal VTE prophylaxis for each group was modified according to condition-specific thrombotic and bleeding risks; 3) guidelines are intended for general information only, are not medical advice, and do not replace professional medical care and/or physician advice.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Soo-Mee
authors.identifier: 0000-0002-0938-3007
authors.initials: SM
authors.lastname: Bang
authors.affiliation: Department of Internal Medicine, School of Medicine, CHA University, Seongnam, Korea.
authors.forename: Moon Ju
authors.identifier: 0000-0001-7440-7573
authors.initials: MJ
authors.lastname: Jang
authors.affiliation: Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
authors.forename: Kyoung Ha
authors.identifier: 0000-0001-8842-4761
authors.initials: KH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Ho-Young
authors.identifier: 0000-0002-1252-5336
authors.initials: HY
authors.lastname: Yhim
authors.affiliation: Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
authors.forename: Yeo-Kyeoung
authors.identifier: 0000-0001-5447-4285
authors.initials: YK
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, VHS Medical Center, Seoul, Korea.
authors.forename: Seung-Hyun
authors.identifier: 0000-0002-5736-2606
authors.initials: SH
authors.lastname: Nam
authors.affiliation: Department of Internal Medicine, Soonchunhyang University College of Medicine, Gumi, Korea.
authors.forename: Hun Gyu
authors.identifier: 0000-0001-9304-7219
authors.initials: HG
authors.lastname: Hwang
authors.affiliation: Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
authors.forename: Sung Hwa
authors.identifier: 0000-0002-5279-6341
authors.initials: SH
authors.lastname: Bae
authors.affiliation: Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Sung-Hyun
authors.identifier: 0000-0002-5051-2413
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
authors.forename: Yeung-Chul
authors.identifier: 0000-0002-1882-3983
authors.initials: YC
authors.lastname: Mun
authors.affiliation: Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
authors.forename: Yang-Ki
authors.identifier: 0000-0003-4221-6689
authors.initials: YK
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.
authors.forename: Inho
authors.identifier: 0000-0002-3135-6312
authors.initials: I
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.
authors.forename: Won-Il
authors.identifier: 0000-0001-7705-0098
authors.initials: WI
authors.lastname: Choi
authors.affiliation: Department of Internal Medicine, Sungkyunkwan University school of medicine, Samsung Medical Center, Seoul, Korea.
authors.forename: Chul Won
authors.identifier: 0000-0002-5474-6807
authors.initials: CW
authors.lastname: Jung
authors.affiliation: Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Korea.
authors.forename: Nan Hee
authors.initials: NH
authors.lastname: Park
authors.affiliation: Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Korea.
authors.forename: Nam-Kyong
authors.identifier: 0000-0003-1153-9928
authors.initials: NK
authors.lastname: Choi
authors.affiliation: Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Byung-Joo
authors.initials: BJ
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, School of Medicine, CHA University, Seongnam, Korea.
authors.forename: Doyeun
authors.identifier: 0000-0002-6981-3144
authors.initials: D
authors.lastname: Oh
mesh_terms: D000367:Age Factors; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D044466:Asian People; D019317:Evidence-Based Medicine; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D061185:Mechanical Thrombolysis; D009369:Neoplasms / Q000150:complications / Q000601:surgery; D056910:Republic of Korea; D018570:Risk Assessment; D013514:Surgical Procedures, Operative / Q000009:adverse effects; D054556:Venous Thromboembolism / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight
keywords: Bleeding; Guideline; Prevention; Venous Thromboembolism