title: [Objective assessment of the functional impact of dry eye severity on the quality of vision by double-pass aberrometry].
abstract: OBJECTIVE
  To assess the functional impact of the severity of dry eye on the quality of vision by measuring an Objective Scatter Index (OSI) using double pass aberrometry.
  
  
  METHODS
  Twenty-eight patients (56 eyes) with dry eye syndromes of varying severity participated in this study. A double-pass aberrometer was used to measure the dynamic changes in the OSI for 20 seconds. The mean and standard deviations of the OSI and the number of blinks occurring during the examination were compared as a function of the clinical severity of dry eye disease.
  
  
  RESULTS
  The mean OSI increased with the severity of dry eye syndrome with a significant difference for stages 3 (P<0.01) and 4 (P<0.001) compared to stages 1 and 2, without a significant difference based on age (P>0.8) or visual acuity (P>0.2). Standard deviation of the OSI also increased with the severity of dry eye disease, with a significant difference for stages 3 (P<0.01) and 4 (P<0.0001) compared to stages 1 and 2, with no significant increase in the number of blinks (P>0.2). The values of the OSI standard deviation represented the dynamic nature of aberrometric changes related to the instability of the tear film.
  
  
  CONCLUSIONS
  Quality of vision of patients deteriorated in relation to the severity of their dry eye. The analysis of OSI standard deviation appears to be an objective way to assess the intensity of subjective visual disturbances reported by patients with dry eye syndrome. It also provides a new tool to assess the severity of damage to the ocular surface.
authors.affiliation: Service d'ophtalmologie, hôpital Bretonneau, CHRU de Tours, 2, boulevard Tonnelé, 37000 Tours, France. Electronic address: thomas.habay@univ-tours.fr.
authors.forename: T
authors.initials: T
authors.lastname: Habay
authors.affiliation: Service d'ophtalmologie, hôpital Bretonneau, CHRU de Tours, 2, boulevard Tonnelé, 37000 Tours, France.
authors.forename: S
authors.initials: S
authors.lastname: Majzoub
authors.affiliation: Service d'ophtalmologie, hôpital Bretonneau, CHRU de Tours, 2, boulevard Tonnelé, 37000 Tours, France.
authors.forename: O
authors.initials: O
authors.lastname: Perrault
authors.affiliation: Service d'ophtalmologie, hôpital Bretonneau, CHRU de Tours, 2, boulevard Tonnelé, 37000 Tours, France.
authors.forename: C
authors.initials: C
authors.lastname: Rousseau
authors.affiliation: Service d'ophtalmologie, hôpital Bretonneau, CHRU de Tours, 2, boulevard Tonnelé, 37000 Tours, France.
authors.forename: P J
authors.initials: PJ
authors.lastname: Pisella
mesh_terms: D057128:Aberrometry; D000368:Aged; D015352:Dry Eye Syndromes / Q000175:diagnosis* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012720:Severity of Illness Index; D014785:Vision, Ocular
keywords: Aberrométrie double passage; Double-pass aberrometry; Dry eye syndrome; Film lacrymal; OQAS; OSI; Qualité de vision; Syndrome sec; Tear film; Vision quality
vernacular_title: Évaluation objective de l'impact fonctionnel de la sévérité de la sécheresse oculaire sur la qualité de vision par aberrométrie double passage.