title: Plexiform angiomyxoid myofibroblastic tumor (PAMT) of the stomach. A case report focusing on its characteristic growth pattern.
abstract: Plexiform angiomyxoid myofibroblastic tumor (PAMT) is a rare mesenchymal tumor of the stomach. We report herein a case with CT findings, which illustrate the characteristic growth pattern of PAMT. A 27-year-old female patient visited our hospital because of epigastric pain and anemia. The CT scan showed a heterogeneous tumor in the gastric antrum, which was drastically enhanced with contrast medium, and consisted of a number of highly stained small nodules around the tumor rim. The resected tumor, 4.6 cm in size, was c-kit negative and SMA-positive by immunohistochemistry, and composed of bland spindle cells which were separated by abundant myxomatous stroma. The tumor showed plexiform growth in the entire stomach wall, with multiple nodules protruding outward within the serosa. The CT findings in this case reflect the characteristic PAMT growth pattern, and are distinct enough to differentiate it from gastrointestinal stromal tumor (GIST).
authors.affiliation: Department of Pathology, Graduate School of Medicine, The University of Tokyo Japan.
authors.forename: Masako
authors.initials: M
authors.lastname: Ikemura
authors.affiliation: Department of Radiology, Graduate School of Medicine, The University of Tokyo Japan.
authors.forename: Eriko
authors.initials: E
authors.lastname: Maeda
authors.affiliation: Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo Japan.
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Hatao
authors.affiliation: Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo Japan.
authors.forename: Susumu
authors.initials: S
authors.lastname: Aikou
authors.affiliation: Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo Japan.
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Seto
authors.affiliation: Department of Pathology, Graduate School of Medicine, The University of Tokyo Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Fukayama
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D049109:Cell Proliferation; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D005743:Gastrectomy; D046152:Gastrointestinal Stromal Tumors / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D058628:Myofibroblasts / Q000737:chemistry / Q000473:pathology*; D009232:Myxoma / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011237:Predictive Value of Tests; D013274:Stomach Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D047368:Tumor Burden
chemical_list: D014408:Biomarkers, Tumor; D003287:Contrast Media
keywords: CT; GIST; PAMT; diagnosis