title: Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery.
abstract: OBJECTIVE
  To review comprehensively the available peer-reviewed published articles in the literature on loteprednol suspension, gel, and ointment in the treatment of ocular inflammation and pain following ocular surgery.
  
  
  METHODS
  We conducted a PubMed literature search review of all published articles on keywords associated with loteprednol etabonate and ocular surgery.
  
  
  RESULTS
  A total of 59 peer-reviewed articles were found in the literature. The focus of the majority of the articles was on the safety and efficacy of loteprednol etabonate 0.5% in postoperative control of inflammation and pain following cataract surgery. There were only three articles with a remote association between loteprednol etabonate and keratoplasty.
  
  
  CONCLUSIONS
  Lotemax® ointment may also have potential as a first-line anti-inflammatory agent of choice in postoperative settings of strabismus and penetrating glaucoma, and following low-risk penetrating keratoplasty procedures.
authors.affiliation: Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia ; Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Amir
authors.initials: A
authors.lastname: Pirouzian
authors.affiliation: Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia ; Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: E Randy
authors.initials: ER
authors.lastname: Craven
keywords: eye; inflammation; keratoplasty; loteprednol; pain; surgery