title: Health state utility of patients with single-level cervical degenerative disc disease: comparison of anterior cervical discectomy and fusion with cervical disc arthroplasty.
abstract: OBJECTIVE
  Cost-effectiveness analysis (CEA) of medical interventions has become increasingly relevant to the discussion of optimization of care. The use of utility scales in CEA permits a quantitative assessment of effectiveness of a given intervention. There are no published utility values for degenerative disc disease (DDD) of the cervical spine, anterior cervical discectomy and fusion (ACDF), or cervical disc replacement (CDR). The purpose of this study was to define health utility values for those health states.
  
  
  METHODS
  The 36-Item Short Form Health Survey data from the ProDisc-C investigational device exemption study were obtained for single-level DDD at baseline and 24 months postoperatively after ACDF or CDR procedures. Patients in the original study were randomized to either ACDF or CDR. Utilizing a commercially available Short Form-6 dimensions program, utility scores were calculated for each health state using a set of parametric preference weights obtained from a sample of the general population using the recognized valuation technique of standard gamble.
  
  
  RESULTS
  The baseline health state utility (HSU) value for a patient with single-level DDD was 0.54 in both the ACDF and CDR groups. Postoperative changes in HSU values were seen in both intervention groups at 24 months. Cervical disc replacement had a HSU value of 0.72. Anterior cervical discectomy and fusion was found to have a postoperative utility state of 0.71. No statistically significant difference was found in the HSU for ACDF and CDR at 24 months of follow-up.
  
  
  CONCLUSIONS
  This study represents the first calculated HSU value for a patient with single-level cervical DDD. Additionally, 2 common treatment interventions for this disease state were assessed. Both treatments were found to have significant impact on the HSU values. These values are integral to future CEA of ACDF and CDR.
authors.affiliation: Department of Orthopaedic Surgery, The Mount Sinai Medical Center, New York, New York;
authors.forename: Sheeraz
authors.initials: S
authors.lastname: Qureshi
authors.forename: Vadim
authors.initials: V
authors.lastname: Goz
authors.forename: Steven
authors.initials: S
authors.lastname: McAnany
authors.forename: Samuel K
authors.initials: SK
authors.lastname: Cho
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Hecht
authors.forename: Rick B
authors.initials: RB
authors.lastname: Delamarter
authors.forename: Michael G
authors.initials: MG
authors.lastname: Fehlings
mesh_terms: D001178:Arthroplasty / Q000191:economics / Q000379:methods*; D002574:Cervical Vertebrae / Q000601:surgery*; D003362:Cost-Benefit Analysis; D003661:Decision Support Techniques; D017586:Diskectomy / Q000191:economics / Q000379:methods*; D005260:Female; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000601:surgery*; D008297:Male; D013123:Spinal Fusion / Q000191:economics / Q000379:methods*; D011795:Surveys and Questionnaires; D059145:Total Disc Replacement / Q000191:economics / Q000379:methods*; D016896:Treatment Outcome