title: Preoperative evaluation of colorectal liver metastases: comparison of gadopentetate dimeglumine and gadoxetic-acid-enhanced 1.5-T MRI.
abstract: OBJECTIVE
  The aim of this study was to compare the diagnostic performance of gadopentetate dimeglumine and gadoxetic-acid-enhanced MRI in patients with colorectal liver metastases.
  
  
  METHODS
  Thirty patients were included and divided into three sets, as follows: gadopentetate dimeglumine set-hepatic arterial phase, portal venous phase, and delay phase; gadoxetic acid set-hepatic arterial phase, portal venous phase, and delay phase; combined set-gadoxetic acid set and hepatobiliary phase. The accuracy was assessed by the area under the alternative-free response receiver operating characteristic curve; the sensitivity and positive predictive value were calculated.
  
  
  RESULTS
  There were 81 colorectal liver metastases in all. Both readers noted higher diagnostic accuracies of the combined set than the other two sets. In the group of small lesions, both readers detected significantly higher sensitivities and positive predictive value on the combined set than the other two sets.
  
  
  CONCLUSIONS
  The combined set showed higher accuracy and sensitivity, especially significantly higher accuracy and sensitivity on small lesions.
authors.affiliation: Department of Radiology, Zhongshan Hospital of Fudan University, No180, Fenglin Road, Xuhui District, Shanghai, China, 200032. Electronic address: ding.ying@zs-hospital.sh.cn.
authors.forename: Ying
authors.initials: Y
authors.lastname: Ding
authors.affiliation: Department of Radiology, Zhongshan Hospital of Fudan University, No180, Fenglin Road, Xuhui District, Shanghai, China, 200032. Electronic address: rao.shengxiang@yahoo.com.cn.
authors.forename: Sheng-Xiang
authors.initials: SX
authors.lastname: Rao
authors.affiliation: Department of Radiology, Zhongshan Hospital of Fudan University, No180, Fenglin Road, Xuhui District, Shanghai, China, 200032. Electronic address: meng.tao0102@yahoo.com.cn.
authors.forename: Tao
authors.initials: T
authors.lastname: Meng
authors.affiliation: Department of Radiology, Zhongshan Hospital of Fudan University, No180, Fenglin Road, Xuhui District, Shanghai, China, 200032. Electronic address: chen.caizhong@yahoo.com.cn.
authors.forename: Caizhong
authors.initials: C
authors.lastname: Chen
authors.affiliation: Department of Radiology, Zhongshan Hospital of Fudan University, No180, Fenglin Road, Xuhui District, Shanghai, China, 200032. Electronic address: li.renchen@yahoo.com.cn.
authors.forename: Renchen
authors.initials: R
authors.lastname: Li
authors.affiliation: Department of Radiology, Zhongshan Hospital of Fudan University, No180, Fenglin Road, Xuhui District, Shanghai, China, 200032. Electronic address: zengmengsu@gmail.com.
authors.forename: Meng-Su
authors.initials: MS
authors.lastname: Zeng
mesh_terms: D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000556:secondary* / Q000601:surgery; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D012372:ROC Curve; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; C073590:gadolinium ethoxybenzyl DTPA; D019786:Gadolinium DTPA
keywords: Colorectal liver metastases; Gadopentetate dimeglumine; Gadoxetic acid; MR imaging