title: Chemotaxis behavior toward an odor is regulated by constant sodium chloride stimulus in Caenorhabditis elegans.
abstract: We studied the chemotaxis behavior of Caenorhabditis elegans toward a chemoattractant in the presence of background sensory stimulus. Chemotaxis toward an odor butanone was greater in the presence of sodium chloride (NaCl) than that without NaCl. By contrast, chemotaxis toward NaCl was not affected by a butanone background. The salt-sensing ASE neuron-deficient che-1(p674) mutants and worms with ASE genetically ablated showed high chemotaxis toward butanone, regardless of the presence of a NaCl background. Therefore, in wild-type worms, information from ASE in the absence of NaCl suppresses butanone chemotaxis, while the suppression is removed in the presence of NaCl.
authors.affiliation: Laboratory of Bioscience, Faculty of Engineering, Iwate University, 4-3-5 Ueda, Morioka 020-8551, Japan. Electronic address: shingai@iwate-u.ac.jp.
authors.forename: Ryuzo
authors.initials: R
authors.lastname: Shingai
authors.affiliation: Laboratory of Bioscience, Faculty of Engineering, Iwate University, 4-3-5 Ueda, Morioka 020-8551, Japan. Electronic address: hichijo@iwate-med.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ichijo
authors.affiliation: Laboratory of Bioscience, Faculty of Engineering, Iwate University, 4-3-5 Ueda, Morioka 020-8551, Japan. Electronic address: wakat@iwate-u.ac.jp.
authors.forename: Tokumitsu
authors.initials: T
authors.lastname: Wakabayashi
authors.affiliation: Laboratory of Bioscience, Faculty of Engineering, Iwate University, 4-3-5 Ueda, Morioka 020-8551, Japan. Electronic address: t2112019@iwate-u.ac.jp.
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Tanaka
authors.affiliation: Laboratory of Bioscience, Faculty of Engineering, Iwate University, 4-3-5 Ueda, Morioka 020-8551, Japan. Electronic address: ogurusu@iwate-u.ac.jp.
authors.forename: Tarou
authors.initials: T
authors.lastname: Ogurusu
mesh_terms: D000818:Animals; D002074:Butanones; D017173:Caenorhabditis elegans; D002633:Chemotaxis / Q000187:drug effects / Q000502:physiology*; D009812:Odorants; D012965:Sodium Chloride / Q000378:metabolism*
chemical_list: D002074:Butanones; D012965:Sodium Chloride
keywords: Butanone; Gustatory neuron; Integration; Nervous system; Olfactory neuron; Sensory information