title: First report of metallo-β-lactamases producing Enterobacter spp. strains from Venezuela.
abstract: Clinical strains of Enterobacter were isolated from Cumana's Central Hospital in Venezuela, and classified as E. cloacae (21), E. aerogenes (7), E. intermedium (1), E. sakazakii (1) and three unclassified. The strains showed high levels of resistance, especially to SXT (58.1%), CRO (48.8%), CAZ (46.6%), PIP (46.4%), CIP (45.2%) and ATM (43.3%). This is the first report for South America of blaVIM-2 in two E. cloacae and one Enterobacter sp., which also showed multiple mechanisms of resistance. Both E. cloacae showed blaTEM-1, but only one showed blaCTX-M-15 gene, while no blaSHV was detected.
authors.affiliation: Lab. Genetica Molecular, IIBCAUDO, Universidad de Oriente, Cumana, Venezuela, Lab. Genetica Molecular, IIBCAUDO, Universidad de Oriente, Cumana, Venezuela.
authors.forename: Dianny
authors.initials: D
authors.lastname: Martínez
authors.affiliation: Lab. Genetica Molecular, IIBCAUDO, Universidad de Oriente, Cumana, Venezuela, Lab. Genetica Molecular, IIBCAUDO, Universidad de Oriente, Cumana, Venezuela.
authors.forename: Hectorina E
authors.initials: HE
authors.lastname: Rodulfo
authors.affiliation: Lab. Bacteriologia, Hospital Universitario Antonio Patricio de Alcalá, Cumaná, Venezuela, Lab. Bacteriologia, Hospital Universitario Antonio Patricio de Alcalá, Cumaná, Venezuela.
authors.forename: Lucy
authors.initials: L
authors.lastname: Rodríguez
authors.affiliation: Lab. Bacteriologia, Hospital Universitario Antonio Patricio de Alcalá, Cumaná, Venezuela, Lab. Bacteriologia, Hospital Universitario Antonio Patricio de Alcalá, Cumaná, Venezuela.
authors.forename: Luisa E
authors.initials: LE
authors.lastname: Caña
authors.affiliation: Lab. Bacteriologia, Hospital Universitario Antonio Patricio de Alcalá, Cumaná, Venezuela, Lab. Bacteriologia, Hospital Universitario Antonio Patricio de Alcalá, Cumaná, Venezuela.
authors.forename: Belkis
authors.initials: B
authors.lastname: Medina
authors.affiliation: Lab. de Bacteriologia Molecular, Dpto. Bioanalisis, Universidad de Oriente, Cumaná, Venezuela, Lab. de Bacteriologia Molecular, Dpto. Bioanalisis, Universidad de Oriente, Cumaná, Venezuela.
authors.forename: Militza
authors.initials: M
authors.lastname: Guzman
authors.affiliation: Lab. Genetica Molecular, IIBCAUDO, Universidad de Oriente, Cumana, Venezuela, Lab. Genetica Molecular, IIBCAUDO, Universidad de Oriente, Cumana, Venezuela.
authors.forename: Numirin
authors.initials: N
authors.lastname: Carreño
authors.affiliation: Instituto Nacional de Higiene Dr Rafael Rangel, Caracas, Venezuela, Instituto Nacional de Higiene Dr Rafael Rangel, Caracas, Venezuela.
authors.forename: Daniel
authors.initials: D
authors.lastname: Marcano
authors.affiliation: Lab. Genetica Molecular, IIBCAUDO, Universidad de Oriente, Cumana, Venezuela, Lab. Genetica Molecular, IIBCAUDO, Universidad de Oriente, Cumana, Venezuela.
authors.forename: Marcos
authors.initials: M
authors.lastname: De Donato
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics*; D003428:Cross Infection / Q000382:microbiology; D004754:Enterobacter / Q000187:drug effects / Q000201:enzymology / Q000235:genetics; D004756:Enterobacteriaceae Infections / Q000382:microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D014687:Venezuela; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001618:beta-Lactamases