title: The combined evidential value of autosomal and Y-chromosomal DNA profiles obtained from the same sample.
abstract: When a Y-chromosomal and a (partial) autosomal DNA profile are obtained from one crime sample, and both profiles match the suspect's profiles, we would like to know the combined evidential value. To calculate the likelihood ratio of observing the autosomal and Y-chromosomal DNA profiles combined, we need to know the conditional random match probability of the observed autosomal DNA profile, given the Y-chromosomal match. We examine this conditional probability in two ways: (1) with a database containing data of 2,085 men and (2) using a simulation model. We conclude that if the Y-chromosomal DNA profiles match, we can still regard the autosomal DNA profile as independent from the Y-chromosomal DNA profile if the matching person is not a descendant of the father of the donor of the (crime) sample. The evidential value can, in that case, be computed by multiplying the random match probabilities of the individual profiles.
authors.affiliation: Korteweg de Vries Instituut voor Wiskunde, University of Amsterdam, Postbus 94248, 1098, XH, Amsterdam, The Netherlands, j.c.dezoete@uva.nl.
authors.forename: Jacob
authors.initials: J
authors.lastname: de Zoete
authors.forename: Marjan
authors.initials: M
authors.lastname: Sjerps
authors.forename: Ronald
authors.initials: R
authors.lastname: Meester
authors.forename: Eric
authors.initials: E
authors.lastname: Cator
mesh_terms: D041322:Chromosomes, Human, Y; D016172:DNA Fingerprinting; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D018895:Microsatellite Repeats; D008957:Models, Genetic