title: Long-term follow-up of off-pump and on-pump coronary artery bypass grafting.
abstract: OBJECTIVE
  Despite increasing recognition of the benefits of off-pump coronary artery bypass grafting (CABG), concerns persist regarding its impact on long-term mortality and freedom from reintervention. In this study, we assessed the impact of off-pump CABG on long-term outcomes.
  
  
  METHODS
  From January 2002 to December 2002, a total of 307 consecutive patients who underwent isolated multivessel off-pump CABG at our institution were compared with a control group of 397 patients who underwent multivessel on-pump CABG during the same period. Perioperative data were prospectively collected and compared. In addition, univariate and risk-adjusted comparisons between the two groups were performed at 10 years.
  
  
  RESULTS
  After adjusting for clinical covariates, off-pump CABG did not emerge as a significant independent predictor of long-term mortality [hazard ratio (HR), 0.91; 95% confidence interval (CI), 0.70-1.12], readmission to hospital for cardiac cause (HR, 0.96; 95% CI, 0.78-1.10), or the need for reintervention (HR, 0.93; 95% CI, 0.87-1.05).
  
  
  CONCLUSIONS
  At long-term follow-up, off-pump CABG remains a safe and effective myocardial revascularization strategy with no adverse impact on survival or freedom from reintervention.
authors.affiliation: From the Departments of *Cardiac Surgery, and †Quality and Safety, Harefield Hospital, London, UK.
authors.forename: Shahzad G
authors.initials: SG
authors.lastname: Raja
authors.forename: Umberto
authors.initials: U
authors.lastname: Benedetto
authors.forename: Dimple
authors.initials: D
authors.lastname: Chudasama
authors.forename: Siobhan
authors.initials: S
authors.lastname: Daley
authors.forename: Mubassher
authors.initials: M
authors.lastname: Husain
authors.forename: Mohamed
authors.initials: M
authors.lastname: Amrani
mesh_terms: D001026:Coronary Artery Bypass / Q000379:methods*; D047549:Coronary Artery Bypass, Off-Pump / Q000379:methods; D003324:Coronary Artery Disease / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate / Q000639:trends; D013997:Time Factors; D016896:Treatment Outcome; D006113:United Kingdom / Q000453:epidemiology