title: Socioeconomic position across the lifecourse & allostatic load: data from the West of Scotland Twenty-07 cohort study.
abstract: BACKGROUND
  We examined how socioeconomic position (SEP) across the lifecourse (three critical periods, social mobility and accumulated over time) is associated with allostatic load (a measure of cumulative physiological burden).
  
  
  METHODS
  Data are from the West of Scotland Twenty-07 Study, with respondents aged 35 (n = 740), 55 (n = 817) and 75 (n = 483). SEP measures representing childhood, the transition to adulthood and adulthood SEP were used. Allostatic load was produced by summing nine binary biomarker scores (1 = in the highest-risk quartile). Linear regressions were used for each of the lifecourse models; with model fits compared using partial F-tests.
  
  
  RESULTS
  For those aged 35 and 55, higher SEP was associated with lower allostatic load (no association in the 75-year-olds). The accumulation model (more time spent with higher SEP) had the best model fit in those aged 35 (b = -0.50, 95%CI = -0.68, -0.32, P = 0.002) and 55 (b = -0.31, 95%CI = -0.49, -0.12, P < 0.001). However, the relative contributions of each life-stage differed, with adulthood SEP less strongly associated with allostatic load.
  
  
  CONCLUSIONS
  Long-term, accumulated higher SEP has been shown to be associated with lower allostatic load (less physiological burden). However, the transition to adulthood may represent a particularly sensitive period for SEP to impact on allostatic load.
authors.affiliation: Scottish Collaboration for Public Health Research & Policy, University of Edinburgh, 20 West Richmond Street, Edinburgh EH8 9DX, UK. tony.robertson@ed.ac.uk.
authors.forename: Tony
authors.initials: T
authors.lastname: Robertson
authors.forename: Frank
authors.initials: F
authors.lastname: Popham
authors.forename: Michaela
authors.initials: M
authors.lastname: Benzeval
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D052636:Allostasis; D015331:Cohort Studies; D005260:Female; D054624:Health Status Disparities; D006801:Humans; D008016:Life Change Events; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012606:Scotland / Q000453:epidemiology; D012923:Social Class