title: Spontaneous coronary artery dissection associated with β-HCG injections and fibromuscular dysplasia.
abstract: Spontaneous coronary artery dissection (SCAD) is an infrequent cause of acute coronary syndrome predominantly affecting younger women. SCAD is often associated with predisposing arterial abnormalities and precipitating emotional, physical, and hormonal stressors. We previously showed that fibromuscular dysplasia is strongly associated with SCAD and may be a causative factor. Hormonal changes related to pregnancy and sex hormones have also been shown to be an important cause of SCAD. We describe the first case report, to our knowledge, of SCAD associated with β-human growth hormone injections in a patient with concomitant FMD.
authors.affiliation: Vancouver General Hospital, Vancouver, British Columbia, Canada.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Lempereur
authors.affiliation: St Paul's Hospital, Vancouver, British Columbia, Canada.
authors.forename: Jasmine
authors.initials: J
authors.lastname: Grewal
authors.affiliation: Vancouver General Hospital, Vancouver, British Columbia, Canada. Electronic address: jsaw@mail.ubc.ca.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Saw
mesh_terms: D002637:Chest Pain / Q000209:etiology; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000008:administration & dosage / Q000009:adverse effects*; D017023:Coronary Angiography; D054059:Coronary Occlusion / Q000000981:diagnostic imaging; D003331:Coronary Vessels / Q000293:injuries*; D005260:Female; D005352:Fibromuscular Dysplasia / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007083:Iliac Artery / Q000000981:diagnostic imaging; D007273:Injections, Intramuscular; D008875:Middle Aged; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000293:injuries; D013318:Stroke Volume; D020107:Troponin T / Q000097:blood; D015431:Weight Loss
chemical_list: D018997:Chorionic Gonadotropin, beta Subunit, Human; D020107:Troponin T