title: Complete remission of Sweet's syndrome after azacytidine treatment for concomitant myelodysplastic syndrome.
abstract: Sweet's syndrome is a rare condition with potentially disabling implications, characterized by painful skin lesions due to neutrophilic dermal infiltration and systemic inflammatory symptoms. A significant proportion of cases is malignancy associated. Hematologic neoplasms, particularly acute myeloid leukemia and myelodysplastic syndromes, are the most commonly associated malignant conditions. Here, we describe the first case of clinical remission of refractory Sweet's syndrome following hypomethylating therapy with azacytidine in a patient with myelodysplastic syndrome who concurrently obtained a complete hematologic response.
authors.affiliation: Section of Hematology, Azienda Ospedaliero-Universitaria S.Anna, Ferrara, Italy, mrtsra@unife.it.
authors.forename: Sara
authors.initials: S
authors.lastname: Martinelli
authors.forename: Gian Matteo
authors.initials: GM
authors.lastname: Rigolin
authors.forename: Genesio
authors.initials: G
authors.lastname: Leo
authors.forename: Roberta
authors.initials: R
authors.lastname: Gafà
authors.forename: Enrico
authors.initials: E
authors.lastname: Lista
authors.forename: Francesca
authors.initials: F
authors.lastname: Cibien
authors.forename: Olga
authors.initials: O
authors.lastname: Sofritti
authors.forename: Giulia
authors.initials: G
authors.lastname: Daghia
authors.forename: Francesco
authors.initials: F
authors.lastname: Cavazzini
authors.forename: Antonio
authors.initials: A
authors.lastname: Cuneo
mesh_terms: D000368:Aged; D001374:Azacitidine / Q000627:therapeutic use*; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D008297:Male; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D012867:Skin / Q000473:pathology; D016463:Sweet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D001374:Azacitidine