title: Dissemination of 16S rRNA methylase ArmA-producing acinetobacter baumannii and emergence of OXA-72 carbapenemase coproducers in Japan.
abstract: Forty-nine clinical isolates of multidrug-resistant Acinetobacter baumannii were obtained from 12 hospitals in 7 prefectures throughout Japan. Molecular phylogenetic analysis revealed the clonal spread of A. baumannii sequence type 208 (ST208) and ST455 isolates harboring the armA gene and ST512 harboring the armA and blaOXA-72 genes. These findings show that A. baumannii isolates harboring armA are disseminated throughout Japan, and this is the first report to show that A. baumannii strains harboring blaOXA-72 and armA are emerging in hospitals in Japan.
authors.affiliation: Department of Infectious Diseases, Research Institute, National Center for Global Health and Medicine, Shinjuku, Tokyo, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Tada
authors.forename: Tohru
authors.initials: T
authors.lastname: Miyoshi-Akiyama
authors.forename: Kayo
authors.initials: K
authors.lastname: Shimada
authors.forename: Masahiro
authors.initials: M
authors.lastname: Shimojima
authors.forename: Teruo
authors.initials: T
authors.lastname: Kirikae
mesh_terms: D040981:Acinetobacter baumannii / Q000201:enzymology*; D001426:Bacterial Proteins / Q000378:metabolism*; D007564:Japan; D008780:Methyltransferases / Q000378:metabolism*; D010802:Phylogeny; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D008780:Methyltransferases; C035181:rRNA (adenosine-O-2'-)methyltransferase; D001618:beta-Lactamases; C063912:carbapenemase