title: Cerebral sinovenous thrombosis in children and neonates: clinical experience, laboratory, treatment, and outcome.
abstract: Our aim is to present the etiology and risk factors for cerebral sinovenous thrombosis (CSVT) and the radiological findings, anticoagulant therapy used, and treatment outcome of patients with CSVT. This study included 12 patients who were treated for CSVT at the Ankara University, School of Medicine, Department of Pediatric Neurology. This study included 5 girls (41.7%) and 7 boys (58.3%) with a mean age of symptom onset of 5.2 ± 6.29 years (range: 0-18 years), who were followed at our institution for a mean of 1.8 ± 1.73 years (range: 0-6.5 years). Among the patients, 3 had no risk factors, 2 had 1 risk factor, and 7 had multiple risk factors. Anticoagulant therapy was administered to 4 patients, of which 1 had neurological sequelae; neurological sequelae or exitus occurred in 4 of the 8 patients who did not receive anticoagulant therapy. The present findings showed that appropriate prophylaxis in appropriately selected patients reduced the rate of recurrence of CSVT.
authors.affiliation: Department of Pediatric Neurology, Ankara University Medical School, Ankara, Turkey bektasomer@gmail.com.
authors.forename: Ömer
authors.initials: Ö
authors.lastname: Bektaş
authors.affiliation: Department of Pediatric Neurology, Ankara University Medical School, Ankara, Turkey.
authors.forename: Serap
authors.initials: S
authors.lastname: Teber
authors.affiliation: Department of Pediatric Molecular Genetics, TOBB ETU Hospital, Ankara, Turkey.
authors.forename: Nejat
authors.initials: N
authors.lastname: Akar
authors.affiliation: Department of Pediatric Hematology, Ankara University Medical School, Ankara, Turkey.
authors.forename: Leyla Zümrüt
authors.initials: LZ
authors.lastname: Uysal
authors.affiliation: Department of Neonatology, Ankara University Medical School, Ankara, Turkey.
authors.forename: Saadet
authors.initials: S
authors.lastname: Arsan
authors.affiliation: Department of Neonatology, Ankara University Medical School, Ankara, Turkey.
authors.forename: Begüm
authors.initials: B
authors.lastname: Atasay
authors.affiliation: Department of Pediatric Neurology, Ankara University Medical School, Ankara, Turkey.
authors.forename: Gülhis
authors.initials: G
authors.lastname: Deda
mesh_terms: D000293:Adolescent; D000925:Anticoagulants / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011859:Radiography; D012189:Retrospective Studies; D012851:Sinus Thrombosis, Intracranial / Q000000981:diagnostic imaging* / Q000188:drug therapy*
chemical_list: D000925:Anticoagulants
keywords: cerebral sinovenous thrombosis; neuroimaging; outcome; pediatric stroke; prophylaxis; treatment