title: [Effects of dezocine on postoperative sore throat after maxillofacial procedures: a comparison with flurbiprofen axetil].
abstract: OBJECTIVE
  To compare the effects between dezocine and flurbiprofen axetil on postoperative sore throat (POST) after maxillofacial procedures.
  
  
  METHODS
  In the study, 90 adult patients with maxillofacial diseases were divided randomly into control group (group C), flurbiprofen group (group F) and dezocine group (group D). Physiological saline, flurbiprofen axetil (1 mg/kg) and dezocine (0.1 mg/kg) were administered intravenously for each group 30 minutes before the end of the operation. We recorded visual analogue scale (VAS) and Bruggrmann comfort scale (BCS) at the time points of 0.5 h, 1 h, 2 h, and 6 h after extubation.
  
  
  RESULTS
  The incidence of POST in group D decreased significantly (P < 0.05). There was no difference between the incidences of groups F and C. The VAS of group F was lower than that of group C (P < 0.01) just at the time points of 0.5 h and 1 h after extubation, from then on, there was no difference between the 2 groups. The VAS of group D was lower than that of group F, and the BCS was higher than that of group F significantly.
  
  
  CONCLUSIONS
  Dezocine has notable analgesia effect for postoperative sore throat, so it is a better choice to carry out postoperative analgesia after maxillofacial procedures.
authors.affiliation: Department of Anesthesiology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Jiao
authors.forename: Rui-chang
authors.initials: RC
authors.lastname: Liu
mesh_terms: D000328:Adult; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000627:therapeutic use*; D004311:Double-Blind Method; D005480:Flurbiprofen / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D019647:Oral Surgical Procedures / Q000009:adverse effects*; D010147:Pain Measurement; D010612:Pharyngitis / Q000188:drug therapy*; D011184:Postoperative Period; D013764:Tetrahydronaphthalenes / Q000627:therapeutic use*
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; D013764:Tetrahydronaphthalenes; D005480:Flurbiprofen; C504422:flurbiprofen axetil; C010827:dezocine