title: [Choroidal thickness assessment with SD-OCT in high myopia with dome-shaped macula].
abstract: OBJECTIVE
  To measure macular choroidal thickness (CT) using spectral-domain optical coherence tomography (SD-OCT) in highly myopic eyes with dome-shaped macula (DSM), and to investigate whether the choroid is thicker in these eyes compared to highly myopic eyes without MB.
  
  
  METHODS
  A cross-sectional study of 200 eyes was performed between January 2010 and June 2012. Twenty-four highly myopic eyes (12%) had a dome-shaped macula. All patients underwent a complete ophthalmological examination, SD-OCT (TOPCON 2000), and B-scan ultrasonography. OCT scans were analyzed in 7 sections, and subfoveal CT was measured manually between the Bruch's membrane and the internal aspect of the sclera. The 20 eyes with isolated dome-shaped macular were paired by age and axial length (AL) with 20 eyes without macular involvement.
  
  
  RESULTS
  In the subgroup with isolated MB, the mean subfoveal CT was 101.86 μm (± 21.35 μm). A statistically significant negative correlation was found between CT and AL (r=-0.623, P=0.0001). The regression equation demonstrated a decrease of 8.3 μm per mm of AL. In the subgroup without MB, matched with the subgroup with MB by age (P=0.591), and AL (P=0.815), the mean subfoveal CT was 89.54 μm (± 20.12 μm). The comparison between the two subgroups found a statistically significant difference in subfoveal CT (P<10-4).
  
  
  CONCLUSIONS
  In our study, choroidal thickness is increased in highly myopic eyes with dome-shaped macula compared to highly myopic eyes without dome-shaped macula. These findings suggest that abnormalities of the choroid may play a role in the pathogenesis of dome-shaped macula.
authors.affiliation: Service d'ophtalmologie B, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-avril, 1006 Tunis, Tunisie. Electronic address: chebilahmed@yahoo.fr.
authors.forename: A
authors.initials: A
authors.lastname: Chebil
authors.affiliation: Service d'ophtalmologie B, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-avril, 1006 Tunis, Tunisie.
authors.forename: B
authors.initials: B
authors.lastname: Ben Achour
authors.affiliation: Service d'ophtalmologie B, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-avril, 1006 Tunis, Tunisie.
authors.forename: N
authors.initials: N
authors.lastname: Chaker
authors.affiliation: Service d'ophtalmologie B, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-avril, 1006 Tunis, Tunisie.
authors.forename: L
authors.initials: L
authors.lastname: Jedidi
authors.affiliation: Service d'ophtalmologie B, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-avril, 1006 Tunis, Tunisie.
authors.forename: F
authors.initials: F
authors.lastname: Mghaieth
authors.affiliation: Service d'ophtalmologie B, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-avril, 1006 Tunis, Tunisie.
authors.forename: L
authors.initials: L
authors.lastname: El Matri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002829:Choroid / Q000473:pathology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008266:Macula Lutea; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications / Q000473:pathology; D012164:Retinal Diseases / Q000150:complications / Q000473:pathology; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods; D055815:Young Adult
keywords: Choroid; Choroïde; Dome-shaped macula; High myopia; Macula bombée; Myopie forte; SD-OCT
vernacular_title: Épaisseur choroïdienne fovéolaire au SD-OCT dans la myopie forte avec macula bombée.