title: The prediction of later neurodevelopmental status of preterm infants at ages 7 to 10 years using the Bayley Infant Neurodevelopmental Screener.
abstract: The aim of this study was to see whether the scores of the Bayley Infant Neurodevelopmental Screener of 45 high-risk preterm infants (gestational age 26-37 wk) between the ages of 3 and 24 months predicted neurodevelopmental status at 7 to 10 years of age. Neurodevelopmental status of 45/122 preterm infants, grouped according to their gestational ages of 26 to 29, 30 to 32, and 33 to 37 weeks, were previously evaluated by Bayley Infant Neurodevelopmental Screener. The scores were categorized as low or high-moderate. Verbal and performance scores of Wechsler Intelligence Scale for Children-Revised (WISC-R) of those patients were assessed between 7 and 10 years. The patients with high-moderate-risk scores of Bayley Infant Neurodevelopmental Screener at all times, regardless of their gestational age, had lower performance, verbal, and total scores of WISC-R than those of who had low Bayley Infant Neurodevelopmental Screener risk scores. High-moderate risk score of Bayley Infant Neurodevelopmental Screener at 7 to 10, and 16 to 20 months, of all patients especially showed good prediction for identifying lower verbal and performance scales. For 7 to 10 months, verbal scale: positive predictive value = 92.3%, negative predictive value = 44.4%, sensitivity = 70.58%, and specificity = 80%; performance scale: positive predictive value = 100%, negative predictive value = 30%, sensitivity = 68.18%, and specificity = 100%. For 16 to 20 months, verbal scale: positive predictive value = 90%, negative predictive value = 37.5%, sensitivity = 64.3%, and specificity = 80%; performance scale: positive predictive value = 90%, negative predictive value = 12.5%, sensitivity = 56.3%, and specificity = 50%. Bayley Infant Neurodevelopmental Screener shows good prediction of later verbal and performance scores of Wechsler Intelligence Scale-Revised for Children as early as 7 to 10 months, which gives us the opportunity to start early intervention.
authors.affiliation: Department of Pediatric Neurology, Gazi University, Medical Faculty, Ankara, Turkey asebnemsoysal@gmail.com.
authors.forename: A Sebnem
authors.initials: AS
authors.lastname: Soysal
authors.affiliation: Department of Pediatric Neurology, Gazi University, Medical Faculty, Ankara, Turkey.
authors.forename: Kivilcim
authors.initials: K
authors.lastname: Gucuyener
authors.affiliation: Department of Pediatric Neonatology, Gazi University, Medical Faculty, Ankara, Turkey.
authors.forename: Ebru
authors.initials: E
authors.lastname: Ergenekon
authors.affiliation: Ok Meydanı Education and Research Hospital, İstanbul, Turkey.
authors.forename: Özden
authors.initials: Ö
authors.lastname: Turan
authors.affiliation: Department of Pediatric Neonatology, Gazi University, Medical Faculty, Ankara, Turkey.
authors.forename: Esin
authors.initials: E
authors.lastname: Koc
authors.affiliation: Department of Pediatric Neonatology, Gazi University, Medical Faculty, Ankara, Turkey.
authors.forename: Canan
authors.initials: C
authors.lastname: Turkyılmaz
authors.affiliation: Department of Pediatric Neonatology, Gazi University, Medical Faculty, Ankara, Turkey.
authors.forename: Esra
authors.initials: E
authors.lastname: Önal
authors.affiliation: Department of Pediatric Neonatology, Gazi University, Medical Faculty, Ankara, Turkey.
authors.forename: Yıldız
authors.initials: Y
authors.lastname: Atalay
mesh_terms: D000704:Analysis of Variance; D002648:Child; D002657:Child Development; D002658:Developmental Disabilities / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007234:Infant, Premature; D007361:Intelligence Tests; D008297:Male; D011379:Prognosis; D012680:Sensitivity and Specificity
keywords: cognition prediction; infant development; long-term follow-up; screening tests