title: Regulatory non-coding RNAs: revolutionizing the RNA world.
abstract: The majority of the genomic DNA sequence in mammalian and other higher organisms can be transcribed into abundant functional RNA transcripts, especially regulatory non-coding RNAs (ncRNAs) that are expressed in a developmentally and species-specific regulated manner. Here, we review various regulatory non-coding RNAs, including regulatory small non-coding RNAs (sncRNAs) and long non-coding RNAs (lncRNAs), and summarize two and eight kinds of distinct modes of action for sncRNAs and lncRNAs respectively, by which functional ncRNAs mediate the regulation of intracellular events.
authors.affiliation: Research Center of Basic Medical Science; Department of Immunology, Basic Medical College; Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Immune Microenvironments and Diseases of Educational Ministry of China, Tianjin Medical University, Tianjin, 300070, China.
authors.forename: Biao
authors.initials: B
authors.lastname: Huang
authors.forename: Rongxin
authors.initials: R
authors.lastname: Zhang
mesh_terms: D000818:Animals; D003593:Cytoplasm / Q000235:genetics; D005809:Genes, Regulator; D035683:MicroRNAs / Q000235:genetics*; D062085:RNA, Long Noncoding / Q000145:classification / Q000235:genetics*; D058727:RNA, Small Untranslated / Q000145:classification / Q000235:genetics*
chemical_list: D035683:MicroRNAs; D062085:RNA, Long Noncoding; D058727:RNA, Small Untranslated