title: New insights into the functional significance of the frontal aslant tract: an anatomo-functional study using intraoperative electrical stimulations combined with diffusion tensor imaging-based fiber tracking.
abstract: We used the method of direct electrostimulation combined with navigated tractography to map the frontal "aslant" tract, enabling us to perform reliable anatomo-functional correlation in a patient undergoing awake surgery to remove a left frontal glioma. The findings enhanced our understanding of the organization of language within the human brain.
authors.affiliation: Department of Neurosurgery, North Hospital, University Hospital of Saint-Etienne , France.
authors.forename: François
authors.initials: F
authors.lastname: Vassal
authors.forename: Claire
authors.initials: C
authors.lastname: Boutet
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Lemaire
authors.forename: Christophe
authors.initials: C
authors.lastname: Nuti
mesh_terms: D000328:Adult; D001931:Brain Mapping; D001932:Brain Neoplasms / Q000175:diagnosis / Q000628:therapy*; D056324:Diffusion Tensor Imaging / Q000379:methods; D004558:Electric Stimulation / Q000379:methods; D005260:Female; D005625:Frontal Lobe / Q000601:surgery*; D005910:Glioma / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D013060:Speech; D014851:Wakefulness
keywords: Broca's area; diffusion tensor imaging; frontal aslant tract; intraoperative stimulation mapping; language; supplementary motor area