title: From stem to roots: Tissue engineering in endodontics.
abstract: The vitality of dentin-pulp complex is fundamental to the life of tooth and is a priority for targeting clinical management strategies. Loss of the tooth, jawbone or both, due to periodontal disease, dental caries, trauma or some genetic disorders, affects not only basic mouth functions but aesthetic appearance and quality of life. One novel approach to restore tooth structure is based on biology: regenerative endodontic procedure by application of tissue engineering. Regenerative endodontics is an exciting new concept that seeks to apply the advances in tissue engineering to the regeneration of the pulp-dentin complex. The basic logic behind this approach is that patient-specific tissue-derived cell populations can be used to functionally replace integral tooth tissues. The development of such 'test tube teeth' requires precise regulation of the regenerative events in order to achieve proper tooth size and shape, as well as the development of new technologies to facilitate these processes. This article provides an extensive review of literature on the concept of tissue engineering and its application in endodontics, providing an insight into the new developmental approaches on the horizon. Key words:Regenerative, tissue engineering, stem cells, scaffold.
authors.affiliation: M.D.S., Post graduate student. Department of conservative dentistry and Endodontics. Govt.Dental college and Research Institute, Bangalore, India.
authors.forename: Rita
authors.initials: R
authors.lastname: Chandki
authors.affiliation: M.D.S., Professor and Head. Department of conservative dentistry and Endodontics. Govt.Dental college and Research Institute, Bangalore, India.
authors.forename: M
authors.initials: M
authors.lastname: Kala
authors.affiliation: M.D.S., Professor and Head. Department of Periodontics. Indraprastha dental college, Ghaziabad,India.
authors.forename: Priyank
authors.initials: P
authors.lastname: Banthia
authors.affiliation: M.D.S., Professor. Department of Periodontics. Modern dental college and research center, Indore, India.
authors.forename: Ruchi
authors.initials: R
authors.lastname: Banthia