title: Enteral nutrition before bowel preparation improves the safety of colonoscopy in the elderly.
abstract: OBJECTIVE
  Adverse events during colonoscopy are more likely to occur in elderly. To avoid the adverse events without decreasing the bowel cleanliness is still an unsolved problem. The aim of this study was to determine the effect of enteral nutrition before colonoscopy in a randomized controlled trail.
  
  
  METHODS
  A total of 108 patients over sixty-five years of age and indicated for colonoscopy were randomized into four groups. Group 1 received a solution of two packages of polyethylene glycol electrolyte powder dissolved in 2000 mL water. Group 2 received 500 mL of enteral nutrition plus polyethylene glycol of the same dosage as in group 1. Group 3 received 200 mL of 25% magnesium sulfate solution. Group 4 received 500 mL of enteral nutrition plus 25% magnesium sulfate solution of the same dosage as in group 3. The intestinal cleaning and various physiological indications were measured before, after bowel preparation, and during colonoscopy.
  
  
  RESULTS
  No significant difference in the quality of colon cleansing was found among the four groups. The incidence of adverse effects in groups 2 and 4 was less than in groups 1 and 3.
  
  
  CONCLUSIONS
  Additional enteral nutrition in elderly patients before bowel preparation did not affect the quality of colon cleansing. However, the process can significantly reduce the incidence of adverse effects.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Yao
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Chen
authors.forename: Gansheng
authors.initials: G
authors.lastname: Zhang
authors.forename: Songbai
authors.initials: S
authors.lastname: Zheng
mesh_terms: D000369:Aged, 80 and over; D002400:Cathartics / Q000008:administration & dosage; D003113:Colonoscopy; D004750:Enteral Nutrition; D005260:Female; D006801:Humans; D008278:Magnesium Sulfate / Q000008:administration & dosage; D008297:Male; D061214:Patient Safety; D011092:Polyethylene Glycols / Q000008:administration & dosage; D011300:Preoperative Care
chemical_list: D002400:Cathartics; D011092:Polyethylene Glycols; D008278:Magnesium Sulfate