title: Imaging myocardium at risk and coronary inflammation in non-ST-segment elevation myocardial infarction: combined use of FDG PET and optical coherence tomography.
abstract: Patients with non-ST-segment elevation myocardial infarction (NSTEMI) represent a heterogeneous group in terms of jeopardized myocardium, pathogenetic mechanisms, and risk of recurrent events. In particular, estimation of myocardium at risk may be challenging before angiography. Yet the mechanisms leading to coronary instability underlying acute coronary syndromes (ACS) have not been completely elucidated. In this report (figure), we describe the potential utility of FDG PET in defining the myocardium at risk and to unravel coronary inflammation in one NSTEMI patient with normal level of C-reactive protein. Optical coherence tomography (OCT) images of culprit lesions are also shown.
authors.affiliation: From the *Istituto di Cardiologia, Dipartimento di Medicina Specialistica Diagnostica eSperimentale Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna, Italy, †Medicina Nucleare, Dipartimento di Medicina Specialistica Diagnostica e Sperimentale Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna, Italy, and ‡Radiologia, Dipartimento di Medicina Specialistica Diagnostica e Sperimentale Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna, Italy.
authors.forename: Nevio
authors.initials: N
authors.lastname: Taglieri
authors.forename: Cristina
authors.initials: C
authors.lastname: Nanni
authors.forename: Francesco
authors.initials: F
authors.lastname: Saia
authors.forename: Luigi
authors.initials: L
authors.lastname: Lovato
authors.forename: Stefano
authors.initials: S
authors.lastname: Fanti
authors.forename: Claudio
authors.initials: C
authors.lastname: Rapezzi
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007249:Inflammation / Q000000981:diagnostic imaging / Q000473:pathology; D064847:Multimodal Imaging; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000473:pathology; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D041623:Tomography, Optical Coherence
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18