title: Two children with obesity-related glomerulopathy identified in a school urinary screening program.
abstract: The incidence of obesity-related glomerulopathy (ORG) has increased over the last decade, but there have been few reports on ORG in Japanese children. Reported herein are two children with ORG identified on school urinary screening (SUS). Patient 1 was a 12-year-old boy in whom proteinuria was first detected on SUS. His body mass index (BMI) was 33.8 kg/m(2) and he had hypertension and hyperuricemia. Patient 2, a 10-year-old boy, also had proteinuria identified on SUS. His BMI was 34.8 kg/m(2) , and he had fatty liver, hyperuricemia, and hypercholesterolemia. Both were diagnosed with ORG based on obesity, proteinuria, and renal pathological findings. After treatment, including candesartan, food restriction and physical exercise, urinary protein excretion was decreased in both cases. We believe that such school urinary screening programs may be effective for the early identification and treatment of children with ORG.
authors.affiliation: Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan.
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Kawasaki
authors.forename: Masato
authors.initials: M
authors.lastname: Isome
authors.forename: Atsushi
authors.initials: A
authors.lastname: Ono
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Kei
authors.initials: K
authors.lastname: Takano
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Suyama
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Hosoya
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis / Q000209:etiology* / Q000652:urine; D008297:Male; D008403:Mass Screening / Q000379:methods*; D009765:Obesity / Q000150:complications* / Q000652:urine; D012574:Schools; D016482:Urinalysis / Q000379:methods
keywords: angiotensin II receptor blocker child; focal segmental glomerulosclerosis; obesity-related glomerulopathy; school urinary screening