title: A practical guide to the treatment of neurogenic orthostatic hypotension.
abstract: Neurogenic orthostatic hypotension (NOH) is a debilitating condition associated with many central and peripheral neurological disorders. It has a complex pathophysiology and variable clinical presentation, which makes diagnosis and treatment difficult. Neurogenic orthostatic hypotension is often confused with other disorders of orthostatic intolerance, hypovolemic states and systemic conditions. Diagnosis is usually made by an autonomic specialist following characteristic responses to head-up tilt. Symptom control can be achieved through a combination of patient education, nonpharmacologic and pharmacologic therapy. The purpose of this review is to provide the clinician with a practical approach to the diagnosis and management of NOH.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Berger
authors.forename: Kurt
authors.initials: K
authors.lastname: Kimpinski
mesh_terms: D001342:Autonomic Nervous System Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D016543:Central Nervous System Neoplasms / Q000150:complications; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use*; D019468:Disease Management; D005081:Exercise Therapy; D005247:Feeding Behavior; D005438:Fludrocortisone / Q000627:therapeutic use; D006801:Humans; D007024:Hypotension, Orthostatic / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D008879:Midodrine / Q000627:therapeutic use; D008901:Mineralocorticoids / Q000627:therapeutic use*; D009103:Multiple Sclerosis / Q000150:complications; D019636:Neurodegenerative Diseases / Q000150:complications; D011729:Pyridostigmine Bromide / Q000627:therapeutic use; D053828:Stockings, Compression; D013566:Sympathomimetics / Q000627:therapeutic use*; D018667:Tilt-Table Test
chemical_list: D002800:Cholinesterase Inhibitors; D008901:Mineralocorticoids; D013566:Sympathomimetics; D008879:Midodrine; D011729:Pyridostigmine Bromide; D005438:Fludrocortisone