title: Syphilis masquerading as focal segmental glomerulosclerosis.
abstract: A patient referred to the genitourinary clinic for positive syphilis serology was found to have symptoms and signs of nephrotic syndrome. A renal biopsy showed focal segmental glomerulosclerosis (FSGS). Doxycycline 200 mg twice daily for 28 days coincided with considerable decrease in proteinuria and rise in serum albumin, suggesting a causal relationship.
authors.affiliation: Newham University Hospital, Barts Health NHS Trust, London, UK anna.hartley@bartshealth.nhs.uk.
authors.forename: A J
authors.initials: AJ
authors.lastname: Hartley
authors.affiliation: The Royal London Hospital, Barts Health NHS Trust, London, UK.
authors.forename: R
authors.initials: R
authors.lastname: Rajakariar
authors.affiliation: The Royal London Hospital, Barts Health NHS Trust, London, UK.
authors.forename: M
authors.initials: M
authors.lastname: Sheaff
authors.affiliation: The Royal London Hospital, Barts Health NHS Trust, London, UK.
authors.forename: M
authors.initials: M
authors.lastname: Buckland
authors.affiliation: The Royal London Hospital, Barts Health NHS Trust, London, UK.
authors.forename: B
authors.initials: B
authors.lastname: Goh
authors.affiliation: Newham University Hospital, Barts Health NHS Trust, London, UK.
authors.forename: R
authors.initials: R
authors.lastname: O'Connell
mesh_terms: D003937:Diagnosis, Differential; D005923:Glomerulosclerosis, Focal Segmental / Q000473:pathology*; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D008297:Male; D013587:Syphilis / Q000175:diagnosis*
keywords: Sexually transmitted infections; Treponema pallidum; doxycycline; focal segmental glomerulosclerosis; glomerulonephritis; late; nephrotic; proteinuria; renal; syphilis