title: A case of myomatous erythrocytosis syndrome associated with a large uterine leiomyoma.
abstract: Several etiologies have been proposed for erythrocytosis associated with uterine leiomyoma. We report a case of erythrocytosis associated with a large uterine leiomyoma, in which specific immunostaining for erythropoietin was positive. A 55-year-old woman, gravida 0, para 0, was referred to our hospital for treatment for a large uterine myoma and erythrocytosis. She had no vaginal bleeding after she reached menopause at 50 years old. She had severe polycythemia: hemoglobin (Hb), 19.9 g/dL; red blood cell count (RBC), 6.65 × 10(6)/mm(3); hematocrit, (Hct) 59.1%. An abdominal simple hysterectomy was performed, and a pathological examination confirmed the diagnosis of leiomyoma of the uterus. In addition, immunostaining demonstrated that the cytoplasm of the leiomyoma cells was strongly positive for erythropoietin. After the operation, the patient's hemoglobin and hematocrit levels normalized, and we diagnosed her condition as myomatous erythrocytosis syndrome.
authors.affiliation: Department of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, Japan ; Department of Obstetrics and Gynecology, University of Toyama, Sugitani 2630, Toyama, Toyama, Japan.
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Ono
authors.affiliation: Department of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Hidaka
authors.affiliation: Department of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, Japan ; Department of Obstetrics and Gynecology, University of Toyama, Sugitani 2630, Toyama, Toyama, Japan.
authors.forename: Kaori
authors.initials: K
authors.lastname: Fukuta
authors.affiliation: Department of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, Japan.
authors.forename: Keiko
authors.initials: K
authors.lastname: Kouchi
authors.affiliation: Department of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, Japan.
authors.forename: Kuniaki
authors.initials: K
authors.lastname: Yasoshima
authors.affiliation: Department of Pathology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, Japan.
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Takagawa
authors.affiliation: Department of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Arai