title: Sex hormone drives blood stem cell reproduction.
abstract: Stem cells ensure the maintenance of tissue homeostasis throughout life by tightly regulating their self-renewal and differentiation. In a recent study published in Nature, Nakada et al, 2014 unveil an unexpected endocrine mechanism that regulates hematopoietic stem cell (HSC) self-renewal.
authors.affiliation: Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Calvanese
authors.forename: Lydia K
authors.initials: LK
authors.lastname: Lee
authors.forename: Hanna K A
authors.initials: HK
authors.lastname: Mikkola
mesh_terms: D000818:Animals; D004967:Estrogens / Q000378:metabolism*; D005260:Female; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000378:metabolism*; D008297:Male; D011247:Pregnancy
chemical_list: D004967:Estrogens