title: Utilization of optical polarization microscopy in the study of sorption characteristics of wound dressing host materials.
abstract: Polarization microscopy was used for evaluation of kinetics of diclofenac sorption in three different wound dressing materials. The sorption kinetics can be evaluated by radii change and intensity of the light traveling through the fiber. The most frequently used host materials for drugs in wound dressings are alginate, polyesters such as polyethylene terephthalate, and viscose. We studied sorption of diclofenac as an example drug. Effective, but rather simple in vitro simulation of diclofenac sorption gives insight into the applicability of the mentioned materials for development of wound healing materials.
authors.affiliation: 1 CE PoliMaT, Tehnološki park 24, SI-1000 Ljubljana, Slovenia.
authors.forename: Miha
authors.initials: M
authors.lastname: Devetak
authors.affiliation: 1 CE PoliMaT, Tehnološki park 24, SI-1000 Ljubljana, Slovenia.
authors.forename: Zdenka
authors.initials: Z
authors.lastname: Peršin
authors.affiliation: 1 CE PoliMaT, Tehnološki park 24, SI-1000 Ljubljana, Slovenia.
authors.forename: Karin
authors.initials: K
authors.lastname: Stana-Kleinschek
authors.affiliation: 1 CE PoliMaT, Tehnološki park 24, SI-1000 Ljubljana, Slovenia.
authors.forename: Uroš
authors.initials: U
authors.lastname: Maver
mesh_terms: D000327:Adsorption; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000493:pharmacokinetics*; D001458:Bandages; D004008:Diclofenac / Q000493:pharmacokinetics*; D006801:Humans; D008859:Microscopy, Polarization / Q000379:methods*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac