title: [Study on percutaneous absorption of xiaozheng zhitong cataplasm].
abstract: OBJECTIVE
  To study the transdermal behavior of Xiaozheng Zhitong cataplasm in rats.
  
  
  METHODS
  With tetrahydropalmatine as the index, the Franz diffusion cell method was adopted for the experiment. Sample content was determined with HPLC.
  
  
  RESULTS
  The transdermal permeability and the transmission rate of tetrahydropalmatine accumulated for 24 h were 20.20% and 0.744 1 microg x cm(-2) x h(-1), respectively.
  
  
  CONCLUSIONS
  The transdermal behaviors of Xiaozheng Zhitong cataplasm were ideal in conformity with the zero order kinetic model.
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Science, Belting 100053, China. baoyanju@126.com
authors.forename: Yan-Ju
authors.initials: YJ
authors.lastname: Bao
authors.affiliation: Institute of Chinese Medicine, China Academy of Chinese Medical Science, Beijing 100700, China.
authors.forename: Mao-Bo
authors.initials: MB
authors.lastname: Du
authors.affiliation: Institute of Chinese Medicine, China Academy of Chinese Medical Science, Beijing 100700, China.
authors.forename: Shu-Zhi
authors.initials: SZ
authors.lastname: Liu
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Science, Belting 100053, China.
authors.forename: Bao-Jin
authors.initials: BJ
authors.lastname: Hua
mesh_terms: D000279:Administration, Cutaneous; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000493:pharmacokinetics*; D005260:Female; D010539:Permeability; D051381:Rats; D017208:Rats, Wistar; D012869:Skin Absorption
chemical_list: D004365:Drugs, Chinese Herbal