title: Refracture of osteoporotic vertebral body concurrent with cement fragmentation at the previously treated vertebral level after balloon kyphoplasty: a case report.
abstract: Kyphoplasty has been shown to provide symptomatic relief of vertebral compression fractures refractory to medical therapy. However, few reports have focused on refracture of cemented vertebrae after kyphoplasty. The presence of cemented vertebrae refracture concurrent with cement fragmentation is an extremely rare condition. We reported an 86-year-old man with a T12 osteoporotic compression fracture undergoing the kyphoplasty treatment. The patient postoperatively continued to have back pain at the same level. The solid lumped polymethylmethacrylate (PMMA) mass and inadequate use and insufficient filling of PMMA cement were observed in postoperative radiographs and magnetic resonance image (MRI) examination. He refused to receive the surgical intervention, but had not strict compliance with oral anti-osteoporotic medications. Ten months postoperatively, refracture of osteoporotic vertebral body concurrent with cement fragmentation occurred at the previously kyphoplasty-treated vertebral level. Bone mineral analysis showed severe osteoporosis with a T-score of -4.0. The patient finally obtained therapeutic benefit of pain relief and bony union of T12 vertebral body by consistently adhering to anti-osteoporotic medication treatment. This case illustrated that patients who underwent kyphoplasty to treat osteoporotic vertebral compression fractures with intravertebral fracture should be strictly followed up and supervised in their anti-osteoporotic medication treatment. The interdigitation injection pattern of PMMA and sufficient PMMA filling with trabeculae in the kyphoplasty procedure also might prevent refracture of the cemented vertebrae concurrent with PMMA fragmentation.
authors.affiliation: Department of Orthopaedic Surgery, The First Affiliated Hospital of Zhejiang University, Qingchun Road 79, Hangzhou, 310003, Zhejiang Province, China.
authors.forename: Xigong
authors.initials: X
authors.lastname: Li
authors.forename: Xianfeng
authors.initials: X
authors.lastname: Lou
authors.forename: Xiangjin
authors.initials: X
authors.lastname: Lin
authors.forename: Junhua
authors.initials: J
authors.lastname: Du
mesh_terms: D000369:Aged, 80 and over; D001843:Bone Cements; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D050815:Fractures, Compression / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D058498:Kyphoplasty / Q000379:methods*; D008297:Male; D010024:Osteoporosis / Q000188:drug therapy; D058866:Osteoporotic Fractures / Q000000981:diagnostic imaging / Q000601:surgery*; D011859:Radiography; D012008:Recurrence; D016103:Spinal Fractures / Q000601:surgery*; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging / Q000293:injuries* / Q000601:surgery
chemical_list: D001843:Bone Cements; D050071:Bone Density Conservation Agents