title: Enhanced external counterpulsation improves peripheral resistance artery blood flow in patients with coronary artery disease.
abstract: Enhanced external counterpulsation (EECP) increases coronary artery perfusion and improves endothelium-dependent vasodilation in peripheral muscular conduit arteries. It is unknown whether vasodilatory capacity is improved in the peripheral resistance vasculature. Here we provide novel evidence from the first randomized, sham-controlled study that EECP increases peak limb blood flow and improves endothelium-dependent vasodilation in both calf and forearm resistance arteries in patients with coronary artery disease.
authors.affiliation: a Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, FL 32611, USA.
authors.forename: Joseph C
authors.initials: JC
authors.lastname: Avery
authors.forename: Darren T
authors.initials: DT
authors.lastname: Beck
authors.forename: Darren P
authors.initials: DP
authors.lastname: Casey
authors.forename: Paloma D
authors.initials: PD
authors.lastname: Sardina
authors.forename: Randy W
authors.initials: RW
authors.lastname: Braith
mesh_terms: D001158:Arteries / Q000503:physiopathology*; D003324:Coronary Artery Disease / Q000503:physiopathology* / Q000628:therapy*; D015908:Counterpulsation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012039:Regional Blood Flow; D014655:Vascular Resistance; D014664:Vasodilation