title: Adolescent-specific patterns of behavior and neural activity during social reinforcement learning.
abstract: Humans are sophisticated social beings. Social cues from others are exceptionally salient, particularly during adolescence. Understanding how adolescents interpret and learn from variable social signals can provide insight into the observed shift in social sensitivity during this period. The present study tested 120 participants between the ages of 8 and 25 years on a social reinforcement learning task where the probability of receiving positive social feedback was parametrically manipulated. Seventy-eight of these participants completed the task during fMRI scanning. Modeling trial-by-trial learning, children and adults showed higher positive learning rates than did adolescents, suggesting that adolescents demonstrated less differentiation in their reaction times for peers who provided more positive feedback. Forming expectations about receiving positive social reinforcement correlated with neural activity within the medial prefrontal cortex and ventral striatum across age. Adolescents, unlike children and adults, showed greater insular activity during positive prediction error learning and increased activity in the supplementary motor cortex and the putamen when receiving positive social feedback regardless of the expected outcome, suggesting that peer approval may motivate adolescents toward action. While different amounts of positive social reinforcement enhanced learning in children and adults, all positive social reinforcement equally motivated adolescents. Together, these findings indicate that sensitivity to peer approval during adolescence goes beyond simple reinforcement theory accounts and suggest possible explanations for how peers may motivate adolescent behavior.
authors.affiliation: The Sackler Institute for Developmental Psychobiology, Weill Cornell Medical College, Box 140, 1300 York Avenue, New York, NY, 10065, USA, rej2004@med.cornell.edu.
authors.forename: Rebecca M
authors.initials: RM
authors.lastname: Jones
authors.forename: Leah H
authors.initials: LH
authors.lastname: Somerville
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.forename: Erika J
authors.initials: EJ
authors.lastname: Ruberry
authors.forename: Alisa
authors.initials: A
authors.lastname: Powers
authors.forename: Natasha
authors.initials: N
authors.lastname: Mehta
authors.forename: Jonathan
authors.initials: J
authors.lastname: Dyke
authors.forename: B J
authors.initials: BJ
authors.lastname: Casey
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior; D000328:Adult; D000367:Age Factors; D001921:Brain / Q000098:blood supply / Q000502:physiology*; D001931:Brain Mapping; D002648:Child; D003463:Cues; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D009042:Motivation; D009483:Neuropsychological Tests; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation; D012056:Reinforcement, Social; D012737:Sex Factors; D055815:Young Adult
chemical_list: D010100:Oxygen