title: Full restoration of spermatogenesis and male fertility after post-traumatic ectopic testis implant.
abstract: OBJECTIVE
  To restore testicular functional competence after traumatic avulsion of the scrotum, accompanied by penile decortication, by means of ad hoc surgery and post-surgical medical treatment.
  
  
  METHODS
  A 26 years old patient underwent a on the job perineal trauma that resulted in loss of one testis while the other one was rescued together with the deferential duct. The spared testis was buried in a subcutaneous thigh pocket after creating a tunnel from the inguinal area. Because of post-traumatic ensued hypogonadism, the patient was treated with corticosteroids, phosphodiesterase 5 inhibitors and anti-oxidizing agents.
  
  
  RESULTS
  Hypogonadism related clinical findings in terms of oligospermia, erectile dysfunction and alterations of the pituitary- testis axis, with low testosterone levels progressively improved along the post-traumatic months. Preservation of testis vascular supply associated with ad hoc medical therapy restored erectile dysfunction and spermatogenesis, and in the end at 6 months of the trauma the patients was able to regain fatherhood capability.
  
  
  CONCLUSIONS
  The obtained results demonstrate that an appropriate testis burying in the subcutaneous thigh region, upon traumatic scrotum avulsion, followed by an ad hoc medical therapy may rescue male fertility. This is unlikely to happen in the clinical routine and previous published reports negate restoration of the testis function, that completely vanishes within 1 year of the intervention.
  
  
  CONCLUSIONS
  Full restoration of testis and penile functions resulted in induction of spontaneous pregnancy in the patient's female partner may occur only if good reconstructive surgery is coupled with an efficient medical therapy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Allegretti
authors.forename: Giovanni
authors.initials: G
authors.lastname: Luca
authors.forename: Iva
authors.initials: I
authors.lastname: Arato
authors.forename: Giulia
authors.initials: G
authors.lastname: Falabella
authors.forename: Andrea
authors.initials: A
authors.lastname: Garolla
authors.forename: Romano
authors.initials: R
authors.lastname: Maffia
authors.forename: Giulia
authors.initials: G
authors.lastname: Ricci
authors.forename: Marco
authors.initials: M
authors.lastname: Ghezzi
authors.forename: Carmine
authors.initials: C
authors.lastname: Alfano
authors.forename: Carlo
authors.initials: C
authors.lastname: Foresta
authors.forename: Riccardo
authors.initials: R
authors.lastname: Calafiore
mesh_terms: D000328:Adult; D005298:Fertility; D006801:Humans; D008297:Male; D012092:Replantation / Q000379:methods*; D012611:Scrotum / Q000293:injuries*; D013091:Spermatogenesis; D013737:Testis / Q000293:injuries* / Q000601:surgery*; D013848:Thigh