title: An autopsy case of refractory vasculo-Behçet's disease.
abstract: Pulmonary vascular involvement in Behçet's disease is a rare complication with a poor prognosis. We present an autopsy case of vasculo-Behçet's disease complicated by pulmonary hemorrhage, possibly caused by rupture of pulmonary artery aneurysms. The patient was treated with a combination of high-dose steroids and pulse cyclophosphamide, but he died from massive hemoptysis. This case highlights the need for potent new therapies for patients with vasculo-Behçet's disease refractory to conventional immunosuppressive therapy, such as a combination of steroids and cyclophosphamide.
authors.affiliation: Division of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine , Kurume , Japan.
authors.forename: Shinjiro
authors.initials: S
authors.lastname: Kaieda
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Zaizen
authors.forename: Yoriko
authors.initials: Y
authors.lastname: Nomura
authors.forename: Koki
authors.initials: K
authors.lastname: Okabe
authors.forename: Seiyo
authors.initials: S
authors.lastname: Honda
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Kage
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ida
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Hoshino
authors.forename: Takaaki
authors.initials: T
authors.lastname: Fukuda
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications / Q000473:pathology*; D006470:Hemorrhage / Q000150:complications / Q000473:pathology*; D006801:Humans; D008171:Lung Diseases / Q000150:complications / Q000473:pathology*; D008297:Male
keywords: Immunosuppressive therapy; Pulmonary artery aneurysm; Vasculitis; Vasculo-Behçet disease