title: Asymmetric hydrogenation of disubstituted furans.
abstract: An enantioselective hydrogenation of disubstituted furans has been developed by using a chiral ruthenium catalyst with N-heterocyclic carbene ligands. This reaction converts furans into valuable enantioenriched disubstituted tetrahydrofurans.
authors.affiliation: NRW Graduate School of Chemistry, Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster, Corrensstrasse 40, 48149 Münster (Germany) http://www.uni-muenster.de/Chemie.oc/glorius/
authors.forename: Jędrzej
authors.initials: J
authors.lastname: Wysocki
authors.forename: Nuria
authors.initials: N
authors.lastname: Ortega
authors.forename: Frank
authors.initials: F
authors.lastname: Glorius
mesh_terms: D002384:Catalysis; D005663:Furans / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry; D006865:Hydrogenation; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry; D011312:Pressure; D012428:Ruthenium / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D005663:Furans; D006571:Heterocyclic Compounds; D012997:Solvents; C030011:carbene; D012428:Ruthenium; D008697:Methane
keywords: asymmetric catalysis; furans; heterocycles; homogeneous catalysis; hydrogenation