title: Adult survivorship of the dengue mosquito Aedes aegypti varies seasonally in central Vietnam.
abstract: The survival characteristics of the mosquito Aedes aegypti affect transmission rates of dengue because transmission requires infected mosquitoes to survive long enough for the virus to infect the salivary glands. Mosquito survival is assumed to be high in tropical, dengue endemic, countries like Vietnam. However, the survival rates of wild populations of mosquitoes are seldom measured due the difficulty of predicting mosquito age. Hon Mieu Island in central Vietnam is the site of a pilot release of Ae. aegypti infected with a strain of Wolbachia pipientis bacteria (wMelPop) that induces virus interference and mosquito life-shortening. We used the most accurate mosquito age grading approach, transcriptional profiling, to establish the survival patterns of the mosquito population from the population age structure. Furthermore, estimations were validated on mosquitoes released into a large semi-field environment consisting of an enclosed house, garden and yard to incorporate natural environmental variability. Mosquito survival was highest during the dry/cool (January-April) and dry/hot (May-August) seasons, when 92 and 64% of Hon Mieu mosquitoes had survived to an age that they were able to transmit dengue (12 d), respectively. This was reduced to 29% during the wet/cool season from September to December. The presence of Ae. aegypti older than 12 d during each season is likely to facilitate the observed continuity of dengue transmission in the region. We provide season specific Ae. aegypti survival models for improved dengue epidemiology and evaluation of mosquito control strategies that aim to reduce mosquito survival to break the dengue transmission cycle.
authors.affiliation: QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
authors.forename: Leon E
authors.initials: LE
authors.lastname: Hugo
authors.affiliation: QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
authors.forename: Jason A L
authors.initials: JA
authors.lastname: Jeffery
authors.affiliation: QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
authors.forename: Brendan J
authors.initials: BJ
authors.lastname: Trewin
authors.affiliation: QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
authors.forename: Leesa F
authors.initials: LF
authors.lastname: Wockner
authors.affiliation: National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
authors.forename: Thi Yen
authors.initials: TY
authors.lastname: Nguyen
authors.affiliation: National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
authors.forename: Hoang Le
authors.initials: HL
authors.lastname: Nguyen
authors.affiliation: Institute Pasteur, Nha Trang, Vietnam.
authors.forename: Le Trung
authors.initials: le T
authors.lastname: Nghia
authors.affiliation: School of Biological Sciences, University of Queensland, St. Lucia, Queensland, Australia.
authors.forename: Emma
authors.initials: E
authors.lastname: Hine
authors.affiliation: QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia ; School of Biological Sciences, Monash University, Melbourne, Victoria, Australia.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Ryan
authors.affiliation: QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
authors.forename: Brian H
authors.initials: BH
authors.lastname: Kay
mesh_terms: D000330:Aedes / Q000382:microbiology / Q000821:virology; D000818:Animals; D003715:Dengue / Q000517:prevention & control / Q000635:transmission; D003716:Dengue Virus / Q000235:genetics / Q000302:isolation & purification*; D007303:Insect Vectors / Q000382:microbiology / Q000821:virology; D012621:Seasons; D014744:Vietnam; D020577:Wolbachia