title: Automatically extracting clinically useful sentences from UpToDate to support clinicians' information needs.
abstract: Clinicians raise several information needs in the course of care. Most of these needs can be met by online health knowledge resources such as UpToDate. However, finding relevant information in these resources often requires significant time and cognitive effort.
  
  
  OBJECTIVE
  To design and assess algorithms for extracting from UpToDate the sentences that represent the most clinically useful information for patient care decision making.
  
  
  METHODS
  We developed algorithms based on semantic predications extracted with SemRep, a semantic natural language processing parser. Two algorithms were compared against a gold standard composed of UpToDate sentences rated in terms of clinical usefulness.
  
  
  RESULTS
  Clinically useful sentences were strongly correlated with predication frequency (correlation= 0.95). The two algorithms did not differ in terms of top ten precision (53% vs. 49%; p=0.06).
  
  
  CONCLUSIONS
  Semantic predications may serve as the basis for extracting clinically useful sentences. Future research is needed to improve the algorithms.
authors.affiliation: Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, USA.
authors.forename: Rashmi
authors.initials: R
authors.lastname: Mishra
authors.affiliation: Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, USA.
authors.forename: Guilherme
authors.initials: G
authors.lastname: Del Fiol
authors.affiliation: Lister Hill Center, National Library of Medicine, Bethesda, MD, USA.
authors.forename: Halil
authors.initials: H
authors.lastname: Kilicoglu
authors.affiliation: Natural Language Processing Group, Mayo Clinic, Rochester, MN, USA.
authors.forename: Siddhartha
authors.initials: S
authors.lastname: Jonnalagadda
authors.affiliation: Lister Hill Center, National Library of Medicine, Bethesda, MD, USA.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Fiszman
mesh_terms: D000465:Algorithms; D019992:Databases as Topic; D020000:Decision Support Systems, Clinical; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods*; D009323:Natural Language Processing; D012660:Semantics