title: Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor.
authors.affiliation: Centre International de Recherche en Infectiologie, Enveloppe Virale et Ingénierie du Retrovirus Team, Institut National de la Santé et de la Recherche Médicale U1111, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5308, Université de Lyon-1, Ecole Normale Supérieure de Lyon, Lyon, France.
authors.forename: Fouzia
authors.initials: F
authors.lastname: Amirache
authors.forename: Camille
authors.initials: C
authors.lastname: Lévy
authors.forename: Caroline
authors.initials: C
authors.lastname: Costa
authors.forename: Philippe-Emmanuel
authors.initials: PE
authors.lastname: Mangeot
authors.forename: Bruce E
authors.initials: BE
authors.lastname: Torbett
authors.forename: Cathy X
authors.initials: CX
authors.lastname: Wang
authors.forename: Didier
authors.initials: D
authors.lastname: Nègre
authors.forename: François-Loïc
authors.initials: FL
authors.lastname: Cosset
authors.forename: Els
authors.initials: E
authors.lastname: Verhoeyen
mesh_terms: D001402:B-Lymphocytes / Q000276:immunology / Q000637:transplantation; D002478:Cells, Cultured; D015316:Genetic Therapy; D005822:Genetic Vectors; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells; D006801:Humans; D016233:Immunotherapy, Active; D016086:Lentivirus; D008213:Lymphocyte Activation; D008562:Membrane Glycoproteins / Q000235:genetics*; D011973:Receptors, LDL / Q000378:metabolism*; D013601:T-Lymphocytes / Q000276:immunology / Q000637:transplantation; D014161:Transduction, Genetic; D017211:Treatment Failure; D014759:Viral Envelope Proteins / Q000235:genetics*; D053586:Virus Internalization
chemical_list: C028391:G protein, vesicular stomatitis virus; D008562:Membrane Glycoproteins; D011973:Receptors, LDL; D014759:Viral Envelope Proteins