title: Straightforward access to 4-membered sulfurated heterocycles: introducing a strategy for the single and double functionalization of thietane 1-oxide.
abstract: A strategy for the stereoselective functionalization of thietane 1-oxide has been developed. Mono (C2 substituted) and doubly (C2, C4 disubstituted) functionalized thietanes have been obtained from the readily available thietane 1-oxide by using the corresponding organometallic intermediates that reacted with electrophiles leaving intact the 4-membered ring.
authors.affiliation: Department of Pharmacy - Drug Sciences, University of Bari "A. Moro", Via E. Orabona 4, Bari 70125 - I, Italy. renzo.luisi@uniba.it.
authors.forename: Laura
authors.initials: L
authors.lastname: Carroccia
authors.forename: Leonardo
authors.initials: L
authors.lastname: Degennaro
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Romanazzi
authors.forename: Corrado
authors.initials: C
authors.lastname: Cuocci
authors.forename: Luisa
authors.initials: L
authors.lastname: Pisano
authors.forename: Renzo
authors.initials: R
authors.lastname: Luisi
mesh_terms: D003499:Cyclic S-Oxides / Q000138:chemical synthesis* / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000737:chemistry*; D015394:Molecular Structure; D013464:Sulfuric Acids / Q000737:chemistry*
chemical_list: D003499:Cyclic S-Oxides; D006571:Heterocyclic Compounds; D013464:Sulfuric Acids; C033158:sulfuric acid