title: Comparison of perinatal and maternal outcomes of severe preeclampsia, eclampsia, and HELLP syndrome.
abstract: OBJECTIVE
  To compare maternal and perinatal outcomes in pregnancies complicated by severe preeclampsia, eclampsia, and HELLP (hemolysis, elevated liver enzyme levels, and low platelets) syndrome.
  
  
  METHODS
  Maternal and neonatal charts of 1,222 consecutive pregnancies complicated by severe preeclampsia, eclampsia, or HELLP syndrome at our maternal-perinatal unit were reviewed. Patients were divided into three groups: 903 (73.9%) with severe preeclampsia, 123 (10.1%) with eclampsia, and 196 (16.0%) with HELLP syndrome.
  
  
  RESULTS
  The overall incidence of adverse maternal outcome was 5.9%. The rates of adverse maternal outcomes for women with HELLP syndrome and eclampsia were higher than for severe preeclampsia (13.8% vs. 11.4% vs. 3.4%, respectively) (p=0.000). Birth weight was lower in patients with HELLP syndrome than in patients with eclampsia and severe preeclampsia (p=0.005). No significant difference in neonatal morbidity was found among the three groups. Perinatal mortality tended to be higher in the severe preeclampsia group than in the HELLP syndrome and eclampsia groups (p=0.231).
  
  
  CONCLUSIONS
  Pregnancies complicated by HELLP syndrome had significantly higher maternal morbidity than those with severe preeclampsia and eclampsia. Perinatal and neonatal outcomes in pregnancies complicated by severe preeclampsia, eclampsia, and HELLP syndrome were dependent on gestational age rather than being disease dependent.
authors.affiliation: İstanbul Bakırköy Women's and Children's Hospital, İstanbul, Turkey.
authors.forename: Gökhan
authors.initials: G
authors.lastname: Yıldırım
authors.affiliation: Mardin Women's and Children's Hospital, Mardin, Turkey.
authors.forename: Kemal
authors.initials: K
authors.lastname: Güngördük
authors.affiliation: Mardin Women's and Children's Hospital, Mardin, Turkey.
authors.forename: Halil
authors.initials: H
authors.lastname: Aslan
authors.affiliation: Mardin Women's and Children's Hospital, Mardin, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Gül
authors.affiliation: Mardin Women's and Children's Hospital, Mardin, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bayraktar
authors.affiliation: Mardin Women's and Children's Hospital, Mardin, Turkey.
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Ceylan
keywords: HELLP syndrome; Severe preeclampsia; eclampsia; perinatal and maternal outcome