title: Visible light photoredox-catalysed intermolecular radical addition of α-halo amides to olefins.
abstract: We present α-chloro amides as a new class of α-acetyl radical precursors, which undergo a tin-free, photoredox-catalysed intermolecular α-alkylation with various olefins exclusively in an anti-Markovnikov fashion. The reaction represents a reductive atom transfer radical addition (ATRA) and provides a series of alkylated amides in good yields.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen, Landoltweg 1, 52074 Aachen, Germany. Magnus.Rueping@rwth-aachen.de.
authors.forename: Masaki
authors.initials: M
authors.lastname: Nakajima
authors.forename: Quentin
authors.initials: Q
authors.lastname: Lefebvre
authors.forename: Magnus
authors.initials: M
authors.lastname: Rueping