title: Klinefelter syndrome - a general practice perspective.
abstract: BACKGROUND
  Klinefelter syndrome (KS) is a common genetic condition affecting one in 450 men, but is only diagnosed in fewer than half of those affected.
  
  
  OBJECTIVE
  To increase awareness among general practitioners of their role in the diagnosis and management of KS.
  
  
  CONCLUSIONS
  KS has a highly varied phenotype comprising a range of physical and psychosocial features and comorbidities. For patients diagnosed with KS, a range of management strategies can be used to improve health outcomes and quality of life.
authors.affiliation: BMedSce (Hons), Medical Student, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, and Department of Clinical Genetics, Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, VIC.
authors.forename: Elyssia
authors.initials: E
authors.lastname: Bourke
authors.forename: Amy
authors.initials: A
authors.lastname: Herlihy
authors.forename: Pamela
authors.initials: P
authors.lastname: Snow
authors.forename: Sylvia
authors.initials: S
authors.lastname: Metcalfe
authors.forename: David
authors.initials: D
authors.lastname: Amor
mesh_terms: D000293:Adolescent; D000368:Aged; D001828:Body Image; D002648:Child; D015897:Comorbidity; D058006:General Practice; D020249:Hormone Replacement Therapy; D006801:Humans; D007248:Infertility, Male / Q000209:etiology / Q000628:therapy; D007713:Klinefelter Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D007859:Learning Disabilities / Q000209:etiology; D008297:Male; D019964:Mood Disorders / Q000209:etiology; D010641:Phenotype; D012017:Referral and Consultation; D012306:Risk; D012657:Self-Help Groups; D013739:Testosterone / Q000627:therapeutic use
chemical_list: D013739:Testosterone