title: Effect of continuous light on spermatogenesis and testicular steroidogenesis in rats: possible involvement of alpha 2u-globulin.
abstract: Male rats exposed to continous light for 70 days showed an increased weights of testis, accessory sex organs, serum levels of FSH, LH, testosterone, testicular 17beta-hydroxysteroid dehydrogenase (1beta-HSD) activity and alpha 2u-globulin, while 3beta-hydroxysteroid dehydrogenase activity showed no significant changes. Prolonged light exposure also stimulated sepermatogenesis in rats. These results suggest that alpha 2u-globulin possibly stimutates the male gonad by inducing pituitary gonadotropins in continuous light-exposed rats.
authors.affiliation: Department of Physiology, College of Medical Sciences, Bharatpur, Chitwan, Nepal. drnmbiswas@gmail.com
authors.forename: N M
authors.initials: NM
authors.lastname: Biswas
authors.affiliation: Department of Physiology, College of Medical Sciences, Bharatpur, Chitwan, Nepal.
authors.forename: R
authors.initials: R
authors.lastname: Biswas
authors.affiliation: Departmental of Medicine, NRS Medical College, Kolkata-14, India.
authors.forename: N M
authors.initials: NM
authors.lastname: Biswas
authors.affiliation: Departmental of Medicine, NRS Medical College, Kolkata-14, India.
authors.forename: Late H
authors.initials: LH
authors.lastname: Mandal
mesh_terms: D015067:17-Hydroxysteroid Dehydrogenases / Q000097:blood; D000510:Alpha-Globulins / Q000378:metabolism*; D000818:Animals; D005640:Follicle Stimulating Hormone / Q000097:blood; D008027:Light; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009929:Organ Size / Q000528:radiation effects; D011863:Radioimmunoassay; D051381:Rats; D013091:Spermatogenesis / Q000528:radiation effects*; D013737:Testis / Q000528:radiation effects*; D013739:Testosterone / Q000097:blood
chemical_list: D000510:Alpha-Globulins; C013803:alpha 2u globulin; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D015067:17-Hydroxysteroid Dehydrogenases; C044256:3 (or 17)-beta-hydroxysteroid dehydrogenase