title: Tools for risk stratification of sudden cardiac death: a review of the literature in different patient populations.
abstract: While various modalities to determine risk of sudden cardiac death (SCD) have been reported in clinical studies, currently reduced left ventricular ejection fraction remains the cornerstone of SCD risk stratification. However, the absolute burden of SCD is greatest amongst populations without known cardiac disease. In this review, we summarize the evidence behind current guidelines for implantable cardioverter defibrillator (ICD) use for the prevention of SCD in patients with ischemic heart disease (IHD). We also evaluate the evidence for risk stratification tools beyond clinical guidelines in the general population, patients with IHD, and patients with other known or suspected medical conditions.
authors.affiliation: Thomas Jefferson University Hospital, Philadelphia, PA, USA.
authors.forename: Loheetha
authors.initials: L
authors.lastname: Ragupathi
authors.affiliation: Thomas Jefferson University Hospital, Philadelphia, PA, USA. Electronic address: behzad.pavri@jefferson.edu.
authors.forename: Behzad B
authors.initials: BB
authors.lastname: Pavri
mesh_terms: D009202:Cardiomyopathies / Q000150:complications / Q000601:surgery; D016757:Death, Sudden, Cardiac / Q000517:prevention & control*; D017147:Defibrillators, Implantable; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D011322:Primary Prevention; D018570:Risk Assessment / Q000379:methods*; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000628:therapy; D013318:Stroke Volume
keywords: Left ventricular dysfunction; Sudden cardiac arrest; Sudden cardiac death; Ventricular fibrillation; Ventricular tachycardia