title: Highly enantioselective kinetic resolution of axially chiral BINAM derivatives catalyzed by a Brønsted acid.
abstract: A highly efficient strategy for the kinetic resolution of axially chiral BINAM derivatives involving a chiral Brønsted acid-catalyzed imine formation and transfer hydrogenation cascade process was developed. The kinetic resolution provides a convenient route to chiral BINAM derivatives in high yields with excellent enantioselectivities.
authors.affiliation: Department of Chemistry, South University of Science and Technology of China, Shenzhen, 518055 (China).
authors.forename: Dao-Juan
authors.initials: DJ
authors.lastname: Cheng
authors.forename: Liang
authors.initials: L
authors.lastname: Yan
authors.forename: Shi-Kai
authors.initials: SK
authors.lastname: Tian
authors.forename: Ming-Yue
authors.initials: MY
authors.lastname: Wu
authors.forename: Lu-Xin
authors.initials: LX
authors.lastname: Wang
authors.forename: Zi-Li
authors.initials: ZL
authors.lastname: Fan
authors.forename: Sheng-Cai
authors.initials: SC
authors.lastname: Zheng
authors.forename: Xin-Yuan
authors.initials: XY
authors.lastname: Liu
authors.forename: Bin
authors.initials: B
authors.lastname: Tan
keywords: BINAM; Brønsted acids; axial chirality; enantioselectivity; kinetic resolution