title: Unmasking Cryptococcal Meningitis Immune Reconstitution Inflammatory Syndrome due to Granulocyte Colony-Stimulating Factor Use in a Patient with a Poorly Differentiated Germ Cell Neoplasm.
abstract: Cryptococcal meningitis immune reconstitution inflammatory syndrome (IRIS) is frequently seen in patients with HIV and less frequently in patients on immune suppressive medications for other conditions. Here, we describe the first reported case of unmasking cryptococcal IRIS due to granulocyte colony-stimulating factor used in an HIV-negative patient with chemotherapy-induced neutropenia.
authors.affiliation: Department of MedicineCenter for Infectious Diseases and Microbiology Translational Research, Minn., USA ; Center for Infectious Diseases and Microbiology Translational Research, Minn., USA ; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, Minn., USA.
authors.forename: Nathan C
authors.initials: NC
authors.lastname: Bahr
authors.affiliation: Department of MedicineCenter for Infectious Diseases and Microbiology Translational Research, Minn., USA.
authors.forename: James
authors.initials: J
authors.lastname: Wallace
authors.affiliation: Department of MedicineCenter for Infectious Diseases and Microbiology Translational Research, Minn., USA ; Center for Infectious Diseases and Microbiology Translational Research, Minn., USA ; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, Minn., USA.
authors.forename: Anne E P
authors.initials: AE
authors.lastname: Frosch
authors.affiliation: Department of MedicineCenter for Infectious Diseases and Microbiology Translational Research, Minn., USA ; Center for Infectious Diseases and Microbiology Translational Research, Minn., USA ; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, Minn., USA.
authors.forename: David R
authors.initials: DR
authors.lastname: Boulware
keywords: Chemotherapy; Cryptococcal meningitis; Granulocyte colony-stimulating factor; Immune reconstitution inflammatory syndrome; Immunosuppressed host