title: Renal hemosiderosis and rapidly progressive glomerulonephritis associated with primary hemochromatosis.
abstract: Hereditary hemochromatosis leads to the accumulation of iron in many organs including the liver, spleen and heart and results in injury and dysfunction of these organs. On the other hand, iron accumulation and functional impairment in kidney is extremely rare. We report a 61-year-old male patient with hereditary hemochromatosis, in whom the renal function was deteriorated rapidly. Renal biopsy revealed crescentic glomeruli and hemosiderin accumulation in tubular epithelial cells.
authors.affiliation: Department of Nephrology, Faculty of Medicine, Eskisehir Osmangazi University , Eskisehir , Turkey .
authors.forename: Sultan
authors.initials: S
authors.lastname: Ozkurt
authors.forename: Mustafa Fuat
authors.initials: MF
authors.lastname: Acikalin
authors.forename: Gokhan
authors.initials: G
authors.lastname: Temiz
authors.forename: Olga Meltem
authors.initials: OM
authors.lastname: Akay
authors.forename: Mehmet
authors.initials: M
authors.lastname: Soydan
mesh_terms: D017809:Fatal Outcome; D005921:Glomerulonephritis / Q000209:etiology*; D006432:Hemochromatosis / Q000150:complications*; D006486:Hemosiderosis / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged
keywords: Cardiac disorders; crescentic glomerulonephritis; diabetes mellitus; hereditary hemochromatosis; liver disease; skin pigmentation