title: Self-gated free-breathing 3D coronary CINE imaging with simultaneous water and fat visualization.
abstract: The aim of this study was to develop a novel technique for acquiring 3-dimensional (3D) coronary CINE magnetic resonance images with both water and fat visualization during free breathing and without external respiratory or cardiac gating. The implemented multi-echo hybrid 3D radial balanced Steady-State Free Precession (SSFP) sequence has an efficient data acquisition and is robust against motion. The k-space center along the slice encoding direction was repeatedly acquired to derive both respiratory and cardiac self-gating signals without an increase in scan time, enabling a free-breathing acquisition. The multi-echo acquisition allowed image reconstruction with water-fat separation, providing improved visualization of the coronary artery lumen. Ten healthy subjects were imaged successfully at 1.5 T, achieving a spatial resolution of 1.0 × 1.0 × 3.0 mm(3) and scan time of about 5 minutes. The proposed imaging technique provided coronary vessel depiction comparable to that obtained with conventional breath-hold imaging and navigator gated free-breathing imaging.
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, New York, United States of America ; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, United States of America.
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, New York, United States of America.
authors.forename: Thanh D
authors.initials: TD
authors.lastname: Nguyen
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, New York, United States of America.
authors.forename: Yanchun
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, New York, United States of America.
authors.forename: Pascal
authors.initials: P
authors.lastname: Spincemaille
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, New York, United States of America.
authors.forename: Martin R
authors.initials: MR
authors.lastname: Prince
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, New York, United States of America.
authors.forename: Jonathan W
authors.initials: JW
authors.lastname: Weinsaft
authors.affiliation: Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, United States of America.
authors.forename: David
authors.initials: D
authors.lastname: Saloner
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, New York, United States of America.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000465:Algorithms; D055424:Cardiac-Gated Imaging Techniques / Q000379:methods*; D003331:Coronary Vessels; D005223:Fats / Q000737:chemistry*; D006321:Heart / Q000502:physiology; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D019047:Phantoms, Imaging; D012119:Respiration; D014867:Water / Q000737:chemistry*
chemical_list: D005223:Fats; D014867:Water