title: RAG1 deficiency with a shifting B cell phenotype and chromosomal instability.
authors.affiliation: Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, 40225 Düsseldorf, Germany. Electronic address: sujal.ghosh@med.uni-duesseldorf.de.
authors.forename: Sujal
authors.initials: S
authors.lastname: Ghosh
authors.affiliation: Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, 40225 Düsseldorf, Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Hönscheid
authors.affiliation: Institute of Transfusion Medicine, University Ulm and Institute for Clinical Transfusion Medicine and Immunogenetics, Ulm, German Red Cross Blood Service, Baden-Wuerttemberg - Hessen, Germany.
authors.forename: Klaus
authors.initials: K
authors.lastname: Schwarz
authors.affiliation: Institute of Human Genetics, Würzburg, Germany.
authors.forename: Katharina
authors.initials: K
authors.lastname: Eirich
authors.affiliation: Institute of Human Genetics, Würzburg, Germany.
authors.forename: Detlev
authors.initials: D
authors.lastname: Schindler
authors.affiliation: Department of Pediatric Hematology and Oncology, University Children's Hospital, University of Bonn, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Schönberger
authors.affiliation: Center for Chronic Immunodeficiency (CCI), University of Freiburg, Germany; Center of Pediatrics, University of Freiburg, Germany.
authors.forename: Carsten
authors.initials: C
authors.lastname: Speckmann
authors.affiliation: Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, 40225 Düsseldorf, Germany.
authors.forename: Arndt
authors.initials: A
authors.lastname: Borkhardt
authors.affiliation: Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, 40225 Düsseldorf, Germany.
authors.forename: Hans-Jürgen
authors.initials: HJ
authors.lastname: Laws
mesh_terms: D000293:Adolescent; D001402:B-Lymphocytes / Q000276:immunology*; D043171:Chromosomal Instability / Q000235:genetics*; D018398:Homeodomain Proteins / Q000235:genetics*; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use; D007153:Immunologic Deficiency Syndromes / Q000235:genetics* / Q000276:immunology*; D007970:Leukopenia; D016131:Lymphocyte Subsets / Q000276:immunology; D008297:Male; D009154:Mutation / Q000235:genetics / Q000276:immunology; D010641:Phenotype
chemical_list: D018398:Homeodomain Proteins; D007074:Immunoglobulin G; C064658:RAG-1 protein