title: Bisphosphonate-induced osteoradionecrosis.
abstract: Bisphosphonates (BPs) are a class of agents used to treat osteoporosis and malignant bone metastasis. Despite these benefits, osteonecrosis of the jaws has recently emerged as a significant complication in a subset of patients receiving these drugs. This case presentation focuses on a 62-year-old man with a 3-year history of monthly use of Zometa (zolendronic acid) for treatment of multiple myeloma, resulting in BP-related osteoradionecrosis of the jaws (BRONJ). This new entity remains a challenge with diagnosis as well as treatment. The goal of this paper is to improve clinicians understanding and provide a guideline for establishing a stage-specific diagnosis and prevention of BRONJ.
authors.affiliation: Department of Oral Pathology and Microbiology, Institute of Dental Sciences and Hospital, Siksha O Anusandhan University, Bhubaneswar, Odisha, India.
authors.forename: Ruchi
authors.initials: R
authors.lastname: Bhuyan
authors.affiliation: Department of Oral Medicine and Radiology, Institute of Dental Sciences and Hospital, Siksha O Anusandhan University, Bhubaneswar, Odisha, India.
authors.forename: Sanat
authors.initials: S
authors.lastname: Bhuyan
authors.affiliation: Department of Oral Medicine and Radiology, Institute of Dental Sciences and Hospital, Siksha O Anusandhan University, Bhubaneswar, Odisha, India.
authors.forename: Rajat G
authors.initials: RG
authors.lastname: Panigrahi
authors.affiliation: Departments of Pedodontia and Preventive Dentistry, Jagadguru Sri Shivarathreeshwara Dental College, Mysore, Karnataka, India.
authors.forename: Antarmayee
authors.initials: A
authors.lastname: Panigrahi
keywords: BRONJ; multiple myeloma; zolendronic acid