title: Advances in pediatric asthma in 2013: coordinating asthma care.
abstract: Last year's "Advances in pediatric asthma: moving toward asthma prevention" concluded that "We are well on our way to creating a pathway around wellness in asthma care and also to utilize new tools to predict the risk for asthma and take steps to not only prevent asthma exacerbations but also to prevent the early manifestations of the disease and thus prevent its evolution to severe asthma." This year's summary will focus on recent advances in pediatric asthma on prenatal and postnatal factors altering the natural history of asthma, assessment of asthma control, and new insights regarding potential therapeutic targets for altering the course of asthma in children, as indicated in Journal of Allergy and Clinical Immunology publications in 2013 and early 2014. Recent reports continue to shed light on methods to understand factors that influence the course of asthma, methods to assess and communicate levels of control, and new targets for intervention, as well as new immunomodulators. It will now be important to carefully assess risk factors for the development of asthma, as well as the risk for asthma exacerbations, and to improve the way we communicate this information in the health care system. This will allow parents, primary care physicians, specialists, and provider systems to more effectively intervene in altering the course of asthma and to further reduce asthma morbidity and mortality.
authors.affiliation: Pediatric Asthma Research Program, Section of Pediatric Pulmonary Medicine, Breathing Institute, Department of Pediatrics, Children's Hospital Colorado, and the Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, Colo. Electronic address: Stanley.Szefler@childrenscolorado.org.
authors.forename: Stanley J
authors.initials: SJ
authors.lastname: Szefler
mesh_terms: D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control; D015415:Biomarkers; D002648:Child; D006801:Humans; D008168:Lung / Q000503:physiopathology; D035683:MicroRNAs / Q000502:physiology; D010372:Pediatrics; D013315:Stress, Psychological / Q000150:complications
chemical_list: D015415:Biomarkers; D035683:MicroRNAs
keywords: Airway remodeling; asthma; asthma control; asthma exacerbations; biomarkers; early intervention in asthma; environment; genetics; inhaled corticosteroids; leukotriene receptor antagonists; long-acting β-adrenergic agonists; personalized medicine; severe asthma; therapeutics