title: Characteristics of hypertension subtypes and treatment outcome among elderly Korean hypertensives.
abstract: There are limited data about characteristics of hypertension subtypes in Asian hypertensive patients and their impacts on treatment of hypertension. This prospective, multi-center, observational study evaluated 2439 hypertensive patients. (≥60 years) Inadequately controlled and drug-naïve patients were categorized into three hypertension subtypes (isolated systolic hypertension [ISH], combined systolic/diastolic hypertension [SDH], and isolated diastolic hypertension [IDH]), and proportions of each hypertension subtype were evaluated. After 6-month strict treatments, we compared the characteristics of patients who did not achieve target BP with those who did. In overall population, ISH was the most common subtype (53.2%; 1297/2439). However, in drug-naïve patients, SDH was the predominant hypertension subtype (59.6%; 260/436). Notably, the proportion of ISH was substantially lower than previously known data. Predictors associated with failure of reaching target BP were old age (>70 years), hypertension awareness, and baseline systolic blood pressure (≥160 mm Hg) for total patients. In drug naïve patients, hypertension awareness, ISH, and microalbuminuria were associated with treatment failure. These findings might have an impact on the evaluations and antihypertensive treatments of elderly Korean patients.
authors.affiliation: Division of Cardiology, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Republic of Korea.
authors.forename: Suk-Won
authors.initials: SW
authors.lastname: Choi
authors.affiliation: Division of Cardiology, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Republic of Korea.
authors.forename: Min-Kyu
authors.initials: MK
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Hangang Sacred Heart Hospital, Seoul, Republic of Korea.
authors.forename: Seong-Woo
authors.initials: SW
authors.lastname: Han
authors.affiliation: Division of Cardiology, Konkuk University Medical Center, Seoul, Republic of Korea.
authors.forename: Sung Hea
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Konkuk University Medical Center, Seoul, Republic of Korea.
authors.forename: Hyun Joong
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Severance Cardiovascular Hospital, Seoul, Republic of Korea.
authors.forename: Seok-Min
authors.initials: SM
authors.lastname: Kang
authors.affiliation: Division of Cardiology, Inje University Busan Paik Hospital, Busan, Republic of Korea.
authors.forename: Dae-Kyeong
authors.initials: DK
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Daedong Hospital, Busan, Republic of Korea.
authors.forename: Byung Soo
authors.initials: BS
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Eul Ji University Hospital, Seoul, Republic of Korea.
authors.forename: Won Ho
authors.initials: WH
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Wonju Christian Hospital, Wonju, Republic of Korea.
authors.forename: Jang-Young
authors.initials: JY
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Bucheon St. Mary's Hospital, Bucheon, Republic of Korea.
authors.forename: Hee-Yeol
authors.initials: HY
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Republic of Korea.
authors.forename: Jay-Young
authors.initials: JY
authors.lastname: Rhew
authors.affiliation: Division of Cardiology, Inha University Hospital, Incheon, Republic of Korea.
authors.forename: Keum-Soo
authors.initials: KS
authors.lastname: Park
authors.affiliation: Division of Cardiology, Kosin University Gospel Hospital, Busan, Republic of Korea.
authors.forename: Kyoung-Im
authors.initials: KI
authors.lastname: Cho
authors.affiliation: Division of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
authors.forename: Myung Ho
authors.initials: MH
authors.lastname: Jeong
authors.affiliation: Department of Internal Medicine, Sunlin Hospital, Busan, Republic of Korea.
authors.forename: Yong Suk
authors.initials: YS
authors.lastname: Jeong
authors.affiliation: Division of Cardiology, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Republic of Korea. Electronic address: khryumd@hanmail.net.
authors.forename: Kyu-Hyung
authors.initials: KH
authors.lastname: Ryu
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000145:classification* / Q000188:drug therapy* / Q000453:epidemiology; D008297:Male; D011446:Prospective Studies; D056910:Republic of Korea / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents
keywords: Elderly; hypertension awareness; isolated systolic hypertension