title: Microfabricated nerve-electrode interfaces in neural prosthetics and neural engineering.
abstract: Neural interfaces and implants are finding more clinical applications and there are rapid technological advances for more efficient and safe design, fabrication and materials to establish high-fidelity neural interfaces. In this review paper, we highlight new developments of the microfabricated electrodes and substrates with regard to the design, materials, fabrication and their clinical applications. There is a noticeable trend towards integration of microfluidic modules on a single neural platform. In addition to the microelectrodes for neural recording and stimulation, microfluidic channels are integrated into a nerve-electrode interface to explore the rich neurochemistry present at the neural interface and exploit it for enhanced electrochemical stimulation and recording of the central and peripheral nervous system.
authors.affiliation: a Division of Engineering , New York University Abu Dhabi (NYUAD) , Abu Dhabi , UAE.
authors.forename: Yong-Ak
authors.initials: YA
authors.lastname: Song
authors.forename: Ahmed M S
authors.initials: AM
authors.lastname: Ibrahim
authors.forename: Amr N
authors.initials: AN
authors.lastname: Rabie
authors.forename: Jongyoon
authors.initials: J
authors.lastname: Han
authors.forename: Samuel J
authors.initials: SJ
authors.lastname: Lin
mesh_terms: D062207:Brain-Computer Interfaces; D004563:Electrochemistry; D006801:Humans; D008839:Microelectrodes; D046210:Microfluidic Analytical Techniques; D055616:Microtechnology; D058117:Neural Prostheses