title: Magnetic nanosensors optimized for rapid and reversible self-assembly.
abstract: Magnetic nanoparticle-based sensors for MRI have been accelerated to a timescale of seconds using densely-functionalized particles of small size. Parameters that increase response rates also result in large nuclear magnetic relaxation rate and light scattering changes, allowing signals to be detected almost immediately after changes in calcium concentration.
authors.affiliation: Departments of Biological Engineering, Brain & Cognitive Sciences, and Nuclear Science & Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA. jasanoff@mit.edu.
authors.forename: Elisenda
authors.initials: E
authors.lastname: Rodriguez
authors.forename: Victor S
authors.initials: VS
authors.lastname: Lelyveld
authors.forename: Tatjana
authors.initials: T
authors.lastname: Atanasijevic
authors.forename: Satoshi
authors.initials: S
authors.lastname: Okada
authors.forename: Alan
authors.initials: A
authors.lastname: Jasanoff
mesh_terms: D015374:Biosensing Techniques; D002118:Calcium / Q000032:analysis* / Q000737:chemistry; D002147:Calmodulin / Q000737:chemistry; D002614:Chelating Agents / Q000737:chemistry; D004492:Edetic Acid / Q000737:chemistry; D005290:Ferric Compounds / Q000737:chemistry*; D060328:Magnetic Phenomena; D008279:Magnetic Resonance Imaging; D053758:Nanoparticles / Q000737:chemistry*
chemical_list: D002147:Calmodulin; D002614:Chelating Agents; D005290:Ferric Compounds; C000499:ferric oxide; D004492:Edetic Acid; D002118:Calcium