title: Histopathological pattern of abnormal uterine bleeding in endometrial biopsies.
abstract: Abnormal uterine bleeding is a common presenting complaint in gyanecology out patient department. Histopathological evaluation of the endometrial samples plays a significant role in the diagnosis of abnormal uterine bleeding. This study was carried out to determine the histopathological pattern of the endometrium in women of various age groups presenting with abnormal uterine bleeding. Endometrial biopsies and curettings of patients presenting with abnormal uterine bleeding was retrospectively studied. A total of 403 endometrial biopsies and curettings were analyzed. The age of the patients ranged from 18 to 70 years. Normal cyclical endometrium was seen in 165 (40.94%) cases, followed by 54 (13.40%) cases of disordered proliferative endometrium and 44 (10.92%) cases of hyperplasia. Malignancy was seen in 10 (2.48%) cases. Hyperplasia and malignancy were more common in the perimenopausal and postmenopausal age groups. Histopathological examination of endometrial biopsies and curettings in patients presenting with abnormal uterine bleeding showed a wide spectrum of changes ranging from normal endometrium to malignancy. Endometrial evaluation is specially recommended in women of perimenopausal and postmenopausal age groups presenting with AUB, to rule out a possibility of any preneoplastic condition or malignancy.
authors.affiliation: Department of Pathology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal. vaidyasujan@gmail.com
authors.forename: S
authors.initials: S
authors.lastname: Vaidya
authors.affiliation: Department of Pathology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal.
authors.forename: M
authors.initials: M
authors.lastname: Lakhey
authors.affiliation: Department of Obstertrics and Gynaecology, Maternity Hospital, Thapathali, Kathmandu, Nepal.
authors.forename: S
authors.initials: S
authors.lastname: Vaidya
authors.affiliation: Department of Obstetrics and Gynaecology, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal.
authors.forename: P K
authors.initials: PK
authors.lastname: Sharma
authors.affiliation: Department of Pathology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal.
authors.forename: S
authors.initials: S
authors.lastname: Hirachand
authors.affiliation: Department of Pathology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal.
authors.forename: S
authors.initials: S
authors.lastname: Lama
authors.affiliation: Department of Pathology, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal.
authors.forename: S
authors.initials: S
authors.lastname: KC
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D014592:Uterine Hemorrhage / Q000473:pathology*