title: Polylactide acid pins versus stainless steel pins in the treatment of diaphyseal fracture: Experimental study in rats.
abstract: In order to develop a biodegradable pin for diaphyseal femoral fracture fixation, polylactide acid (PLA) pins were implanted in the femoral bone of rats. A distal diaphyseal fracture was performed. Union and tissue reaction to PLA pins versus stainless steel pins was studied after 15 days, and 1, 2 and 6 months of implantation. PLA and stainless steel pins induced the same union and a similar tissue reaction during the 6-month period. Biocompatibility of material was satisfactory.
authors.affiliation: Paediatric Orthopaedic Surgery, Faculty of Medicine, University of Nice-Sophia-Antipolis, Hospital Archet, B.P. 3079, 06202 Nice Cedex 3, France, griffet.j@chu-nice.fr.
authors.forename: J
authors.initials: J
authors.lastname: Griffet
authors.forename: E
authors.initials: E
authors.lastname: Accorsi
authors.forename: A
authors.initials: A
authors.lastname: Chevallier
authors.forename: T
authors.initials: T
authors.lastname: El Hayek
authors.forename: G
authors.initials: G
authors.lastname: Odin
authors.forename: W
authors.initials: W
authors.lastname: Meouchy