title: Effects of intravaginally inserted controlled-release dinoprostone and oxytocin for labor induction on umbilical cord blood gas parameters.
abstract: OBJECTIVE
  To compare the effects of oxytocin and dinoprostone used in labor induction on fetal blood gas parameters.
  
  
  METHODS
  This prospective randomized trial involved 108 women who completed 37 gestational weeks and who required labor induction prior to normal vaginal birth. Labor was induced in 57 women with an intravenous low dose oxytocin regimen and in 51 with intravaginal dinoprostone (PGE2). Following childbirth, umbilical artery blood gas was analyzed, with pH, pCO2, pO2, HCO3 and base excess (BE) compared in the two groups.
  
  
  RESULTS
  Mean age and obstetrical data (gravidity, parity, gestational weeks and birthweight) were similar in the two groups (p>0.05). All infants had 1 and 5 minute APGAR scores ≥7. Umbilical artery blood pH was similar in the oxytocin and dinoprostone groups (7.31±0.07 vs. 7.31±0.05, p=0.780), as were the other blood gas parameters (pCO2, pO2, base excess and HCO3; p>0.05 each).
  
  
  CONCLUSIONS
  Induction of labor with either oxytocin or dinoprostone in women with uncomplicated term pregnancies had no adverse effects on umbilical artery blood gas parameters.
authors.affiliation: Department of Obstetrics and Gynecology, Ankara Atatürk Education and Research Hospital, Ankara, Turkey.
authors.forename: Hüseyin Levent
authors.initials: HL
authors.lastname: Keskin
authors.affiliation: Department of Obstetrics and Gynecology, Ankara Atatürk Education and Research Hospital, Ankara, Turkey.
authors.forename: Gökalp
authors.initials: G
authors.lastname: Kabacaoğlu
authors.affiliation: Department of Obstetrics and Gynecology, Ankara Atatürk Education and Research Hospital, Ankara, Turkey.
authors.forename: Elçin İşlek
authors.initials: Eİ
authors.lastname: Seçen
authors.affiliation: Department of Obstetrics and Gynecology, Ankara Atatürk Education and Research Hospital, Ankara, Turkey.
authors.forename: Işık
authors.initials: I
authors.lastname: Ustüner
authors.affiliation: Department of Obstetrics and Gynecology, Ankara Atatürk Education and Research Hospital, Ankara, Turkey.
authors.forename: Gülin
authors.initials: G
authors.lastname: Yeğin
authors.affiliation: Department of Obstetrics and Gynecology, Ankara Atatürk Education and Research Hospital, Ankara, Turkey.
authors.forename: Ayşe Filiz
authors.initials: AF
authors.lastname: Avşar
keywords: Oxytocin; dinoproston; labor induction; pH; umbilical artery blood gas