title: Overoxidized polyimidazole/graphene oxide copolymer modified electrode for the simultaneous determination of ascorbic acid, dopamine, uric acid, guanine and adenine.
abstract: In the present work, a novel strategy based on overoxidized polyimidazole (PImox) and graphene oxide (GO) copolymer modified electrode was proposed for the simultaneous determination of ascorbic acid (AA), dopamine (DA), uric acid (UA), guanine (G) and adenine (A). The copolymer was characterized by the scanning electron microscopy (SEM), atomic force microscopy (AFM), Fourier transform infrared (FT-IR), X-ray photoelectron spectroscopy (XPS) and electrochemical impedance spectroscopy (EIS). Due to the synergistic effects between PImox and GO, the proposed electrode exhibited excellent electrochemical catalytic activities and high selectivity and sensitivity toward the oxidation of AA, DA, UA, G and A. The peak separations between AA and DA, AA and UA, UA and G, and G and A were 140 mV, 200 mV, 380 mV and 300 mV, respectively. The linear response ranges for AA, DA, UA, G and A were 75-2275 μM, 12-278 μM, 3.6-249.6 μM, 3.3-103.3 μM and 9.6-215 μM, respectively, and corresponding detection limits were 18 μM, 0.63 μM, 0.59 μM, 0.48 μM and 1.28 μM.
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
authors.forename: Xiaofang
authors.initials: X
authors.lastname: Liu
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
authors.forename: Ling
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. Electronic address: shapingw@swu.edu.cn.
authors.forename: Shaping
authors.initials: S
authors.lastname: Wei
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. Electronic address: cshong@swu.edu.cn.
authors.forename: Shihong
authors.initials: S
authors.lastname: Chen
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
authors.forename: Xin
authors.initials: X
authors.lastname: Ou
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
authors.forename: Qiyi
authors.initials: Q
authors.lastname: Lu
mesh_terms: D000225:Adenine / Q000032:analysis*; D001205:Ascorbic Acid / Q000032:analysis*; D015374:Biosensing Techniques / Q000191:economics / Q000379:methods; D004298:Dopamine / Q000032:analysis*; D055664:Electrochemical Techniques / Q000191:economics / Q000379:methods; D004566:Electrodes; D006108:Graphite / Q000737:chemistry; D006147:Guanine / Q000032:analysis*; D007093:Imidazoles / Q000737:chemistry*; D057230:Limit of Detection; D010084:Oxidation-Reduction; D011108:Polymers / Q000737:chemistry*; D014527:Uric Acid / Q000032:analysis*
chemical_list: D007093:Imidazoles; D011108:Polymers; D014527:Uric Acid; D006147:Guanine; D006108:Graphite; D000225:Adenine; D001205:Ascorbic Acid; D004298:Dopamine
keywords: Graphene oxide; Polyimidazole; Simultaneous determination; Small biomolecules