title: [Delayed wound healing during therapy of cutaneous graft-versus-host disease with everolimus].
abstract: Graft-versus-host-disease (GvHD) is despite improvement in transplantation medicine the major cause for morbidity and mortality after allogeneic stem cell transplantation. We describe a patient with chronic cutaneous GvHD who developed massive skin ulcerations after changing the immunosuppressive therapy to a mammalian target of rapamycin (mTOR)-inhibitor.
authors.affiliation: Klinik und Poliklinik für Dermatologie und Venerologie, Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Brown
authors.forename: D
authors.initials: D
authors.lastname: Neumayer
authors.forename: Z
authors.initials: Z
authors.lastname: Rafieé-Tari
authors.forename: T
authors.initials: T
authors.lastname: Krieg
authors.forename: S A
authors.initials: SA
authors.lastname: Eming
mesh_terms: D000068338:Everolimus; D006086:Graft vs Host Disease / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D020123:Sirolimus / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D012883:Skin Ulcer / Q000139:chemically induced* / Q000517:prevention & control; D033581:Stem Cell Transplantation / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D000068338:Everolimus; D020123:Sirolimus