title: Perinatal outcome of twin pregnancies after early transvaginal multifetal pregnancy reduction.
abstract: OBJECTIVE
  To compare the pregnancy outcomes of twin pregnancies following early transvaginal multifetal pregnancy reduction (MPR) with nonreduced twin gestations.
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  Two tertiary medical centers.
  
  
  METHODS
  A cohort of 77 multiple pregnancies after reduction to twins and 78 dichorionic-diamniotic nonreduced twins.
  
  
  METHODS
  Early fetal reduction.
  
  
  METHODS
  Pregnancy outcome.
  
  
  RESULTS
  Triplet pregnancies reduced to twins (n = 55) and nonreduced twin pregnancies (n = 78) had comparable outcomes. The rates of preterm delivery ≤32 weeks (1.9% vs. 1.4%) and ≤34 weeks of gestation (15.1% vs. 19.2%) were similar among both groups. There was no difference in the mean gestational age (36.54 vs. 36.35 weeks) or mean birth weight (2,365 vs. 2,365 g) between the two groups. Similarly, there was no significant difference in the incidence of gestational diabetes (15.1% vs. 14.1%) and intrauterine growth retardation (IUGR; 1.9% vs. 9%) between the two groups. The incidence of gestational hypertension was higher in the study group (24.5% vs. 9%), but it was not associated with an increased risk for prematurity or IUGR.
  
  
  CONCLUSIONS
  The perinatal outcome of twin pregnancies after early transvaginal fetal reduction from triplets seems to be comparable to the outcome of nonreduced twin pregnancies.
authors.affiliation: Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel. Electronic address: jigalh@hotmail.com.
authors.forename: Jigal
authors.initials: J
authors.lastname: Haas
authors.affiliation: Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel.
authors.forename: Ariel
authors.initials: A
authors.lastname: Hourvitz
authors.affiliation: Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel.
authors.forename: Jehoshua
authors.initials: J
authors.lastname: Dor
authors.affiliation: Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel; Department of Obstetrics and Gynecology, Assuta Medical Center, Tel Aviv, Israel.
authors.forename: Shai
authors.initials: S
authors.lastname: Elizur
authors.affiliation: Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel.
authors.forename: Yoav
authors.initials: Y
authors.lastname: Yinon
authors.affiliation: Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel.
authors.forename: Eran
authors.initials: E
authors.lastname: Barzilay
authors.affiliation: Department of Obstetrics and Gynecology, Assuta Medical Center, Tel Aviv, Israel; Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel.
authors.forename: Adrian
authors.initials: A
authors.lastname: Shulman
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018743:Perinatal Care / Q000639:trends*; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology; D018873:Pregnancy Rate / Q000639:trends*; D018607:Pregnancy Reduction, Multifetal / Q000009:adverse effects / Q000639:trends*; D059286:Pregnancy, Triplet; D059285:Pregnancy, Twin; D011446:Prospective Studies; D013997:Time Factors
keywords: MPR; transvaginal fetal reduction