title: [Genital lymphedema associated with Crohn's disease].
abstract: BACKGROUND
  Crohn's disease is a chronic inflammatory intestinal pathology which can be associated to different extra-digestive manifestations. We reported a case of recurrent genital lymphedema leading to Crohn's disease diagnosis.
  
  
  METHODS
  A 49-year-old man was referred for increased penis and scrotal volume, associated with recurrent febrile flare during the 10 previous years. Clinically, we noted an inflammatory penis and scrotum lymphedema. Clinical urological examination, and biological, bacteriological, computer-tomography examinations were negative. Metastatic Crohn's disease was diagnosed in association with concomitant severe terminal ileitis. Treatment with corticosteroids and azathioprine resulted in significant decrease of inflammatory genital lymphedema.
  
  
  CONCLUSIONS
  Genital inflammatory lymphedema occurs during inflammatory, infectious, and tumor diseases. Some cases of metastatic genital lymphedema related to Crohn's disease are described, most often in children. Inflammatory genital lymphedema associated with gastrointestinal symptoms may suggest Crohn's disease.
authors.affiliation: Service de dermatologie, hôpital Sud, CHU d'Amiens, avenue René Laënnec - Salouel, 80054 Amiens cedex 1, France.
authors.forename: C
authors.initials: C
authors.lastname: Garny de La Rivière
authors.affiliation: Service de dermatologie, hôpital Sud, CHU d'Amiens, avenue René Laënnec - Salouel, 80054 Amiens cedex 1, France. Electronic address: acaudron02@gmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Caudron
authors.affiliation: Cabinet de gastro-entérologie, 9, avenue d'Irlande, 80090 Amiens, France.
authors.forename: B
authors.initials: B
authors.lastname: Heyman
authors.affiliation: Service de dermatologie, hôpital Sud, CHU d'Amiens, avenue René Laënnec - Salouel, 80054 Amiens cedex 1, France.
authors.forename: C
authors.initials: C
authors.lastname: Lok
mesh_terms: D003424:Crohn Disease / Q000150:complications*; D005832:Genital Diseases, Male / Q000209:etiology; D006801:Humans; D008209:Lymphedema / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010409:Penile Diseases / Q000209:etiology*; D012611:Scrotum
keywords: Crohn's disease; Genital lymphedema; Lymphœdème génital; Maladie de Crohn; Maladie de Crohn métastatique; Metastatic Crohn's disease