title: A strongly CD34-positive meningioma that was difficult to distinguish from a solitary fibrous tumor.
abstract: Fibrous or transitional meningioma and solitary fibrous tumor (SFT) are frequently difficult to differentiate from each other on the basis of histopathology. It is extremely unusual for a meningioma to exhibit diffuse, strongly positive immunoreactivity for cluster of differentiation 34 (CD34), and this has never been previously reported from a histopathological specimen. A patient with transitional meningioma that exhibited strongly positive for CD34, which has been regarded as characteristic of SFT and is considered to be useful for distinguishing the latter from meningioma, is reported.
authors.affiliation: Department of Neurosurgery and.
authors.forename: Tomu
authors.initials: T
authors.lastname: Okada
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Fujitsu
authors.forename: Teruo
authors.initials: T
authors.lastname: Ichikawa
authors.forename: Shigeo
authors.initials: S
authors.lastname: Mukaihara
authors.forename: Kousuke
authors.initials: K
authors.lastname: Miyahara
authors.forename: Shin
authors.initials: S
authors.lastname: Tanino
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Uriu
authors.forename: Takahiro
authors.initials: T
authors.lastname: Sakamoto
authors.forename: Syunsuke
authors.initials: S
authors.lastname: Hataoka
authors.forename: Jyunichi
authors.initials: J
authors.lastname: Kubota
authors.forename: Kouji
authors.initials: K
authors.lastname: Suzuki
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Niino
authors.forename: Saburou
authors.initials: S
authors.lastname: Yagishita
mesh_terms: D018952:Antigens, CD34 / Q000096:biosynthesis; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008577:Meningeal Neoplasms / Q000175:diagnosis*; D008579:Meningioma / Q000175:diagnosis*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000648:ultrastructure*; D054364:Solitary Fibrous Tumors / Q000175:diagnosis*
chemical_list: D018952:Antigens, CD34; D014408:Biomarkers, Tumor
keywords: CD34; electron microscopy; immunoreactivity; meningioma; solitary fibrous tumor