title: Awareness of and knowledge about mother-to-child infections in Japanese pregnant women.
abstract: To reduce the incidence of infants with congenital infections, women should be aware of and know prevention measures against maternal infection with mother-to-child infections during pregnancy. Our objective was to assess the awareness of and knowledge about mother-to-child infections in Japanese pregnant women. A survey of 343 Japanese pregnant women was completed. Awareness of 13 pathogens capable of mother-to-child transmission was surveyed. Knowledge about the transmission route, the most susceptible time of infection that may cause severe fetal disease during pregnancy, and methods to prevent maternal infection were investigated for four major pathogens (cytomegalovirus, rubella virus, Toxoplasma gondii, and parvovirus B19) and results were compared between these pathogens. The proportion of women aware of pathogens concerning TORCH syndrome was the following: rubella virus 76%, Treponema pallidum 69%, Toxoplasma gondii 58%, parvovirus B19 28%, herpes simplex virus 27%, and cytomegalovirus 18%. Only 8% knew how cytomegalovirus is transmitted, and only 12% knew how parvovirus B19 is transmitted; both were significantly lower than those who knew transmission routes for rubella virus or Toxoplasma gondii. The proportion of women who knew the most susceptible time for severe fetal infection by maternal acquisition of cytomegalovirus, Toxoplasma gondii, or parvovirus B19 was significantly lower than that for rubella virus. The vast majority of surveyed women were not aware of methods to prevent maternal infection with cytomegalovirus or parvovirus B19. In conclusion, current awareness of and knowledge about cytomegalovirus and parvovirus B19 infection are low in Japanese pregnant women.
authors.affiliation: Department of Pediatrics, Kobe University Hospital, Kobe, Japan.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Morioka
authors.forename: Ayako
authors.initials: A
authors.lastname: Sonoyama
authors.forename: Shinya
authors.initials: S
authors.lastname: Tairaku
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Ebina
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nagamata
authors.forename: Mayumi
authors.initials: M
authors.lastname: Morizane
authors.forename: Kenji
authors.initials: K
authors.lastname: Tanimura
authors.forename: Kazumoto
authors.initials: K
authors.lastname: Iijima
authors.forename: Hideto
authors.initials: H
authors.lastname: Yamada
mesh_terms: D000328:Adult; D003587:Cytomegalovirus / Q000302:isolation & purification / Q000472:pathogenicity; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007564:Japan; D009035:Mothers; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000382:microbiology* / Q000821:virology*; D012412:Rubella virus / Q000302:isolation & purification / Q000472:pathogenicity; D014122:Toxoplasma / Q000302:isolation & purification / Q000472:pathogenicity
keywords: Toxoplasma gondii; cytomegalovirus; parvovirus B19; pregnant women; rubella virus