title: [Cardiovascular risks of combined oral contraceptives - beyond the French controversy].
abstract: Combined hormonal contraceptive is the most used contraceptive method in France among childbearing-aged women. Following the temporary delisting of oral contraception containing a 3rd generation progestin and following the market withdrawal of oral pills containing cyproterone acetate in combination with ethynil-estradiol (35μg), the impact of these events on our prescribing practice remains to determine. We will especially discuss the cardiovascular risk associated with combined hormonal contraceptives in the light of the most recent publications either with epidemiological or biological data.
authors.forename: H
authors.initials: H
authors.lastname: Gronier
authors.affiliation: Centre hospitalier inter-communal de Poissy Saint-Germain, 10, rue Champ-Gaillard, 78303 Poissy cedex, France. Electronic address: hgronier@chi-poissy-st-germain.fr.
authors.forename: H
authors.initials: H
authors.lastname: Gronier-Gouvernel
authors.affiliation: Service de gynécologie endocrinienne et médecine de la reproduction, hôpital Jeanne-de-Flandre, centre hospitalier régional universitaire de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France; Service de gynécologie médicale, orthogénie et médecine du couple, hôpital Jeanne-de-Flandre, centre hospitalier régional universitaire de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France.
authors.forename: G
authors.initials: G
authors.lastname: Robin
mesh_terms: D002318:Cardiovascular Diseases; D003277:Contraceptives, Oral, Combined / Q000009:adverse effects*; D003280:Contraceptives, Oral, Synthetic / Q000009:adverse effects; D004967:Estrogens / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D005602:France; D006801:Humans; D016912:Levonorgestrel; D011372:Progestins / Q000008:administration & dosage / Q000009:adverse effects; D012307:Risk Factors; D054556:Venous Thromboembolism
chemical_list: D003277:Contraceptives, Oral, Combined; D003280:Contraceptives, Oral, Synthetic; D004967:Estrogens; D011372:Progestins; D016912:Levonorgestrel
keywords: Accident vasculaire cérébral; Accidents thrombo-emboliques veineux; Combined oral contraception; Contraception orale estro-progestative; Deep venous thromboembolism; Infarctus du myocarde; Myocardial infarction; Stroke