title: Oral lesions associated with Nevirapine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: A report of 10 cases.
abstract: Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are closely related severe, acute mucocutaneous reactions usually caused by drugs. They are acute life-threatening conditions and cause widespread necrosis of the epithelium. There is persistence of a high risk of SJS or TEN in relation to human immunodeficiency virus (HIV) infection associated with exposure to nevirapine (NVP). In this article, we present nine cases of SJS and one case of TEN in HIV-seropositive individuals who developed cutaneous, oral, ocular and genital lesions while being treated with NVP.
authors.affiliation: Department of Oral Pathology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.
authors.forename: Ramana Bv
authors.initials: RB
authors.lastname: Reddy
authors.affiliation: Department of Oral Pathology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.
authors.forename: P Chandra
authors.initials: PC
authors.lastname: Shekar
authors.affiliation: Department of Oral Pathology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.
authors.forename: K Lalith Prakash
authors.initials: KL
authors.lastname: Chandra
authors.affiliation: Department of Oral Pathology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.
authors.forename: Rs
authors.initials: R
authors.lastname: Aravind
keywords: Drug reaction; HIV; Steven–Johnson; nevirapine; toxic epidermal necrolysis