title: A human pluripotent stem cell platform for assessing developmental neural toxicity screening.
abstract: A lack of affordable and effective testing and screening procedures mean surprisingly little is known about the health hazards of many of the tens of thousands of chemicals in use in the world today. The recent rise in the number of children affected by neurological disorders such as autism has stirred valuable debate about the role chemicals play in our daily life, highlighting the need for improved methods of assessing chemicals for developmental neural toxicity.
authors.forename: Zhonggang
authors.initials: Z
authors.lastname: Hou
authors.forename: Jue
authors.initials: J
authors.lastname: Zhang
authors.forename: Michael P
authors.initials: MP
authors.lastname: Schwartz
authors.forename: Ron
authors.initials: R
authors.lastname: Stewart
authors.forename: C David
authors.initials: CD
authors.lastname: Page
authors.forename: William L
authors.initials: WL
authors.lastname: Murphy
authors.forename: James A
authors.initials: JA
authors.lastname: Thomson
mesh_terms: D000818:Animals; D020869:Gene Expression Profiling; D006801:Humans; D020100:Hydrogels / Q000737:chemistry; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods; D017628:Microglia / Q000166:cytology / Q000187:drug effects; D055495:Neurogenesis; D020286:Pericytes / Q000166:cytology / Q000187:drug effects; D039904:Pluripotent Stem Cells / Q000166:cytology*; D014118:Toxins, Biological / Q000633:toxicity
chemical_list: D020100:Hydrogels; D014118:Toxins, Biological