title: A stochastic model for kinesin bidirectional stepping.
abstract: In this paper, a hand-over-hand stochastic model for the dynamics of the conventional kinesin is constructed. In the model, both forward and backward motions are taken into consideration. First passage time distributions, average velocities, dwell times, and forward/backward step ratios are investigated based on the model. A good agreement between the results of the model and experimental data is achieved under a variety of external loads.
authors.affiliation: School of Physics, Shandong University, Jinan 250100, China.
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Yao
authors.affiliation: School of Physics, Shandong University, Jinan 250100, China.
authors.forename: Yujun
authors.initials: Y
authors.lastname: Zheng
mesh_terms: D000244:Adenosine Diphosphate / Q000737:chemistry; D000255:Adenosine Triphosphate / Q000737:chemistry; D016547:Kinesins / Q000737:chemistry*; D008870:Microtubules / Q000737:chemistry; D015233:Models, Statistical; D056004:Molecular Dynamics Simulation; D009010:Monte Carlo Method
chemical_list: D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D016547:Kinesins