title: Hydroxy functionalization of non-activated C-H and C=C bonds: new perspectives for the synthesis of alcohols through biocatalytic processes.
abstract: New perspectives through enzymes: Recent breakthroughs have been achieved in the selective hydroxy functionalization of non-activated C-H and C=C bonds. Enzymes turned out to be suitable catalysts for the ω-hydroxylation of (substituted) alkanes and regioselective hydroxylation of aromatic hydrocarbons with atmospheric oxygen as the oxidant, and the asymmetric addition of water to non-activated alkenes.
authors.affiliation: Faculty of Chemistry, Bielefeld University, Universitätsstrasse 25, 33615 Bielefeld (Germany). harald.groeger@uni-bielefeld.de.
authors.forename: Harald
authors.initials: H
authors.lastname: Gröger
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D055162:Biocatalysis; D002384:Catalysis; D006900:Hydroxylation; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000438:Alcohols
keywords: alcohols; biocatalysis; enzyme catalysis; hydration; hydroxylation