title: A new isothermal nucleic acid detection strategy mediated by a double-nicked beacon.
abstract: A new isothermal and cascade signal amplification method for sensitive nucleic acid detection was developed, which is ultra-simple because it only depends on one double-nicked beacon.
authors.affiliation: State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China. sc169@163.com.
authors.forename: Cuiping
authors.initials: C
authors.lastname: Ma
authors.forename: Dianang
authors.initials: D
authors.lastname: Han
authors.forename: Chao
authors.initials: C
authors.lastname: Shi
mesh_terms: D045744:Cell Line, Tumor; D053904:DNA Breaks, Single-Stranded; D003850:Deoxyribonuclease I / Q000378:metabolism; D006801:Humans; D035683:MicroRNAs / Q000032:analysis / Q000302:isolation & purification; D021141:Nucleic Acid Amplification Techniques; D009696:Nucleic Acids / Q000032:analysis*; D012313:RNA / Q000302:isolation & purification / Q000378:metabolism; D013050:Spectrometry, Fluorescence
chemical_list: D035683:MicroRNAs; D009696:Nucleic Acids; D012313:RNA; D003850:Deoxyribonuclease I