title: (11)CH4 molecule production using a NaBH4 target for (11)C ion acceleration.
abstract: Solid-state materials suitable for use as proton irradiation targets were investigated for producing high-purity (11)CH4 molecules for heavy-ion cancer therapy. The radioactivity of gas produced by proton irradiation was measured for several target materials. Also, the radioactive molecular species of the produced gas were analyzed by radio gas chromatography. We found that 5 × 10(12) (11)C molecules could be collected by proton irradiation on a NaBH4 target. We also found that the (11)CH4 molecules were produced and collected directly from the irradiated target, owing to the hydrogen atoms bound in the solid-state NaBH4.
authors.affiliation: National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Katagiri
authors.affiliation: National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan.
authors.forename: Koutaro
authors.initials: K
authors.lastname: Nagatsu
authors.affiliation: National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan.
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Minegishi
authors.affiliation: National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan.
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Suzuki
authors.affiliation: National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Hojo
authors.affiliation: National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Muramatsu
authors.affiliation: National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Honma
authors.affiliation: National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kitagawa
authors.affiliation: National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Noda
authors.affiliation: National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Noda
mesh_terms: D001894:Borohydrides; D002250:Carbon Radioisotopes; D008697:Methane; D010315:Particle Accelerators / Q000295:instrumentation*
chemical_list: D001894:Borohydrides; D002250:Carbon Radioisotopes; C025364:sodium borohydride; D008697:Methane