title: Mild and novel electrochemical preparation of β-cyclodextrin/graphene nanocomposite film for super-sensitive sensing of quercetin.
abstract: A mild and novel preparation tactics based on electrochemical techniques for the fabrication of electro-deposited graphene (E-GR) and polymerized β-cyclodextrin (P-βCD) nanocomposite film were developed. The structure and morphology of GR-based nanocomposite were investigated by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Raman spectroscopy. Simultaneously, the electrochemical properties of this nanocomposite were characterized by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Based on the synergistic effect of E-GR and P-βCD, a super-sensitive electrochemical sensor for quercetin was successfully fabricated. Under optimum conditions, the determination range for quercetin was from 0.005 to 20 µM with a low detection limit of 0.001 µM (S/N=3). Moreover, this sensor also displays excellent sensitivity, fine reproducibility and stability. To further study the practical applicability of the proposed sensor, the determination of real samples was carried out with satisfactory results.
authors.affiliation: Department of Chemistry, Shanghai Key Laboratory of Modern Metallurgy & Materials Processing, School of Materials Science and Engineering, Shanghai University, Shanghai 200444, PR China; School of Chemistry & Chemical Engineering, Linyi University, Linyi 276005, PR China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Technical Center for Animal Plant and Food Inspection and Quarantine, Shanghai Entry-Exit Inspection and Quarantine Bureau, Shanghai 200135, China.
authors.forename: Shuqing
authors.initials: S
authors.lastname: Gu
authors.affiliation: Department of Chemistry, Shanghai Key Laboratory of Modern Metallurgy & Materials Processing, School of Materials Science and Engineering, Shanghai University, Shanghai 200444, PR China. Electronic address: wdingyp@sina.com.
authors.forename: Yaping
authors.initials: Y
authors.lastname: Ding
authors.affiliation: Department of Chemistry, Shanghai Key Laboratory of Modern Metallurgy & Materials Processing, School of Materials Science and Engineering, Shanghai University, Shanghai 200444, PR China.
authors.forename: Mingju
authors.initials: M
authors.lastname: Shen
authors.affiliation: Department of Chemistry, Shanghai Key Laboratory of Modern Metallurgy & Materials Processing, School of Materials Science and Engineering, Shanghai University, Shanghai 200444, PR China.
authors.forename: Lin
authors.initials: L
authors.lastname: Jiang
mesh_terms: D055664:Electrochemical Techniques / Q000379:methods*; D006108:Graphite / Q000737:chemistry*; D057230:Limit of Detection; D031239:Lonicera / Q000737:chemistry; D053761:Nanocomposites / Q000737:chemistry*; D058105:Polymerization; D011794:Quercetin / Q000032:analysis*; D013662:Tea / Q000737:chemistry; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D013662:Tea; D047392:beta-Cyclodextrins; D006108:Graphite; D011794:Quercetin; C031215:betadex
keywords: Differential pulse voltammetry; Electro-deposited grapheme; Nanocomposite film; Polymerized β-cyclodextrin; Quercetin