title: Clinicopathological features of dacryolithiasis in Japanese patients: frequent association with infection in aged patients.
abstract: Purpose. The purpose of this study is to elucidate the clinicopathological features of dacryolithiasis and prevalence of associated infection in Japanese patients. Materials and Methods. Out of 13,471 outclinic patients from 2006 to 2011, 268 patients were scheduled to be performed dacryocystorhinostomy (DCR) due to dacryocystitis with nasolacrimal duct obstruction. Actually 266 patients underwent dacryocystorhinostomy (DCR) and two patients were cured by only ophthalmic examination. Dacryoliths were found in 17 cases (6.3%). Among 17 cases of dacryolithiasis, three patients were male, and 14 were female. The age of the patients ranged from 32 to 82 (mean 67) years, and 13 cases (76%) were more than 65 years of age. Pathological examination disclosed the infectious agents in 9 cases (53%), and all patients with infection were more than 65 years of age. Special stains revealed colonies of fungus, suspicious of Aspergillus, in 6 cases and gram-positive rods, and suspicious of Actinomyces, in 3 cases. Conclusions. The current study showed the frequent association of infection with dacryolithiasis in aged Japanese patients. This should be taken into the consideration for the treatment of dacryolithiasis.
authors.affiliation: Fukiage Eye Clinic, 2-10 Fukiage, Hachinohe 031-0003, Japan.
authors.forename: Masabumi
authors.initials: M
authors.lastname: Kubo
authors.affiliation: Department of Ophthalmology, Aomori Prefectural Central Hospital, 2-1-1 Higashi Tsukurimichi, Aomori 030-8553, Japan.
authors.forename: Tomoki
authors.initials: T
authors.lastname: Sakuraba
authors.affiliation: Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Japan.
authors.forename: Ryuichi
authors.identifier: 0000-0003-4669-7061
authors.initials: R
authors.lastname: Wada