title: [Malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma of the penis: a case report].
abstract: We report the case of a malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma (MFH/UPS) of the penis in a 78-years-old-man who had undergone previous radical prostatectomy, external beam radiation therapy for prostatic adenocarcinoma. The mass was a 9-cm firm lesion at the base of the penis predominantly composed of malignant spindle cells arranged in sweeping fascicles and storiform pattern. The tumor cells stained for vimentin, beta-smooth muscle actin, S-100, and were negative for keratin, desmin, Melan A, PSA. Despite total penectomy, he developed a local reccurence 4 months after surgery, and died from dissemination 6 months after surgery. This is the 8th case of penile MFH/UPS.
authors.affiliation: Department of Urology, Fujisawa City Hospital. sugiura-shm@tu.gc-broad.net
authors.forename: Shimpei
authors.initials: S
authors.lastname: Sugiura
authors.affiliation: Department of Urology, Fujisawa City Hospital.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Tatenum
authors.affiliation: Department of Urology, Fujisawa City Hospital.
authors.forename: Ryoko
authors.initials: R
authors.lastname: Sakata
authors.affiliation: Department of Urology, Fujisawa City Hospital.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Tajiri
authors.affiliation: Department of Urology, Fujisawa City Hospital.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kitami
authors.affiliation: Department of Pathology, Fujisawa City Hospital.
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Gondo
authors.affiliation: Department of Pathology, Kanagawa Cancer Center.
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Kameda
mesh_terms: D000199:Actins / Q000032:analysis; D000230:Adenocarcinoma / Q000628:therapy*; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D017809:Fatal Outcome; D051677:Histiocytoma, Malignant Fibrous / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D016609:Neoplasms, Second Primary; D010412:Penile Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D010413:Penis / Q000601:surgery*; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000628:therapy*; D011878:Radiotherapy / Q000379:methods; D009418:S100 Proteins / Q000032:analysis; D012509:Sarcoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D014746:Vimentin / Q000032:analysis
chemical_list: C541116:ACTA2 protein, human; D000199:Actins; D014408:Biomarkers, Tumor; D009418:S100 Proteins; D014746:Vimentin