title: Point/Counterpoint. Future radiotherapy practice will be based on evidence from retrospective interrogation of linked clinical data sources rather than prospective randomized controlled clinical trials.
authors.affiliation: Knowledge Engineering Department, MAASTRO Clinic, Maastricht 6229 ET, The Netherlands.
authors.forename: Andre L A J
authors.initials: AL
authors.lastname: Dekker
authors.affiliation: Department of Physics, Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, Surrey SM2 5PT, United Kingdom.
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Gulliford
authors.forename: Martin A
authors.initials: MA
authors.lastname: Ebert
authors.forename: Colin G
authors.initials: CG
authors.lastname: Orton
mesh_terms: D019317:Evidence-Based Medicine; D006801:Humans; D009369:Neoplasms / Q000532:radiotherapy; D011446:Prospective Studies; D011878:Radiotherapy / Q000379:methods* / Q000639:trends*; D016032:Randomized Controlled Trials as Topic; D012107:Research Design; D012189:Retrospective Studies