title: Patient with chest pain refractory to proton pump inhibitor: report of a case of eosinophilic esophagitis.
abstract: Eosinophilic esophagitis (EoE) is the most common form of gastrointestinal disorders associated with eosinophilia. Typically, an inappropriate accumulation of eosinophils is found in the esophageal mucosa. EoE can be well managed and treated with several options that include an elimination diet, drug therapy (oral and topical steroids) and esophageal dilatations. We herein, report a case of a 49-year-old male affected by EoE associated to chest pain, treated with proton pump inhibitor without clinical response. The patient suffered from long lasting postprandial fullness and gastroesophageal reflux disease-like symptoms. He had a history of episodic asthmatic attacks and allergic rhinitis but had not dysphagia or food impaction. The patient recovered completely after an adequate treatment.
authors.affiliation: Department of Internal Medicine and Medical Specialties, Gastroenterology Unit, "La Sapienza" University, Rome.
authors.forename: E V
authors.initials: EV
authors.lastname: Avallone
authors.affiliation: Department of Internal Medicine and Medical Specialties, Gastroenterology Unit, "La Sapienza" University, Rome.
authors.forename: C
authors.initials: C
authors.lastname: Cassieri
authors.affiliation: Unit of Gastroenterology and Digestive Endoscopy, Sandro Pertini Hospital, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Zippi
authors.affiliation: Unit of Gastroenterology and Digestive Endoscopy, Sandro Pertini Hospital, Rome, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Pica
authors.affiliation: Department of Internal Medicine and Medical Specialties, Gastroenterology Unit, "La Sapienza" University, Rome.
authors.forename: A
authors.initials: A
authors.lastname: Marcheggiano
authors.affiliation: Department of Internal Medicine and Medical Specialties, Gastroenterology Unit, "La Sapienza" University, Rome.
authors.forename: P
authors.initials: P
authors.lastname: Vernia
authors.affiliation: Department of Internal Medicine and Medical Specialties, Gastroenterology Unit, "La Sapienza" University, Rome.
authors.forename: E S
authors.initials: ES
authors.lastname: Corazziari
authors.affiliation: Department of Internal Medicine and Medical Specialties, Gastroenterology Unit, "La Sapienza" University, Rome.
authors.forename: P
authors.initials: P
authors.lastname: Paoluzi
mesh_terms: D002637:Chest Pain / Q000209:etiology*; D057765:Eosinophilic Esophagitis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*
chemical_list: D054328:Proton Pump Inhibitors