title: The association between body mass index and mortality on peritoneal dialysis: a prospective cohort study.
abstract: BACKGROUND
  Previous studies have demonstrated that increased body mass index (BMI) is associated with decreased mortality in hemodialysis (HD) patients. However, the association between BMI and survival has not been well established in patients undergoing peritoneal dialysis (PD). The aim of the study was to determine the association between BMI and mortality in the PD population using the Clinical Research Center (CRC) registry for end-stage renal disease (ESRD) cohort in Korea.
  
  
  METHODS
  Prevalent patients with PD were selected from the CRC registry for ESRD, a prospective cohort study on dialysis patients in Korea. Patients were categorized into four groups by quartiles of BMI. Cox regression analysis was used to calculate the adjusted hazard ratio (HR) of mortality with a BMI of quartile 2 (21.4 - 23.5 kg/m(2)) as the reference.
  
  
  RESULTS
  A total of 900 prevalent patients undergoing PD were included. The median follow-up period was 24 months. The multivariate Cox proportional hazard model showed that the lowest quartile of BMI was associated with higher mortality (HR 3.00, 95% confidence interval (CI), 1.26 - 7.15). However, the higher quartiles of BMI were not associated with mortality compared with the reference category of BMI quartile 2 (Quartile 3: HR 1.11, 95% CI, 0.43 - 2.85, Quartile 4: HR 1.64, 95% CI, 0.66 - 4.06) after adjustment for clinical variables.
  
  
  CONCLUSIONS
  Lower BMI was a significant risk factor for death, but increased BMI was not associated with mortality in Korean PD patients.
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Yong Kyun
authors.initials: YK
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Su-Hyun
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Hyung Wook
authors.initials: HW
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Young Ok
authors.initials: YO
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Dong Chan
authors.initials: DC
authors.lastname: Jin
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Ho Chul
authors.initials: HC
authors.lastname: Song
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Euy Jin
authors.initials: EJ
authors.lastname: Choi
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Yong-Lim
authors.initials: YL
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Yon-Su
authors.initials: YS
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Shin-Wook
authors.initials: SW
authors.lastname: Kang
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Nam-Ho
authors.initials: NH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Korea; Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea; Department of Internal Medicine, Chonnam National University Medical School, Korea.
authors.forename: Chul Woo
authors.initials: CW
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002423:Cause of Death; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007676:Kidney Failure, Chronic / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000401:mortality*; D016016:Proportional Hazards Models; D011446:Prospective Studies; D012042:Registries; D012044:Regression Analysis; D056910:Republic of Korea; D012307:Risk Factors; D016019:Survival Analysis
keywords: Body mass index; mortality; peritoneal dialysis