title: Cu(I)-catalyzed regio- and stereoselective [6 + 3] cycloaddition of azomethine ylides with tropone: an efficient asymmetric access to bridged azabicyclo[4.3.1]decadienes.
abstract: An unprecedented Cu(I)-catalyzed asymmetric [6 + 3] cycloaddition of tropone with azomethine ylides was reported, which performs well over a broad scope of substrates and offers a unique and facile access to the synthetically useful bridged azabicyclo[4.3.1]decadiene derivatives in good yields with high levels of diastereoselectivities and enantioselectivities under mild conditions.
authors.affiliation: College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, China 430072.
authors.forename: Huai-Long
authors.initials: HL
authors.lastname: Teng
authors.forename: Lu
authors.initials: L
authors.lastname: Yao
authors.forename: Chun-Jiang
authors.initials: CJ
authors.lastname: Wang
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D053961:Azabicyclo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D001391:Azo Compounds / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D061565:Cycloaddition Reaction; D008958:Models, Molecular; D013237:Stereoisomerism; D013882:Thiosemicarbazones / Q000737:chemistry*; D014334:Tropolone / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D000475:Alkenes; D053961:Azabicyclo Compounds; D001391:Azo Compounds; D013882:Thiosemicarbazones; C512188:azomethine; D003300:Copper; D014334:Tropolone; C003730:tropone