title: Marchiafawa bignami disease possibly related to consumption of a locally brewed alcoholic beverage: Report of two cases.
abstract: Marchiafava Bignami disease is a rare toxic disease seen mostly in chronic alcoholics, resulting in progressive demyelination and necrosis of the corpus callosum. Initially it was thought to be specific to individuals in central Italy, consuming large amounts of Chianti red wine; however, alcoholic beverages worldwide are presently implicated. In our case series of two cases, locally made "illicit" liquor (Mahuwa Alcohol) could be the causative factor. In radiological point of view typically the corpus callosum is affected, with involvement of the body, genu, and splenium in order of occurrence. Occasionally the entire callosum may be also involved. Clinical presentation varies from case to case.
authors.affiliation: Department of Psychiatry, Jagjivan Ram Hospital, Mumbai, Maharashtra, India.
authors.forename: Jagdeo P
authors.initials: JP
authors.lastname: Rawat
authors.affiliation: BYL Nair Hospital and Topiwala National Medical College, Mumbai, Maharashtra, India.
authors.forename: Charles
authors.initials: C
authors.lastname: Pinto
authors.affiliation: Department of Psychiatry, Jagjivan Ram Hospital, Mumbai, Maharashtra, India.
authors.forename: Kapil S
authors.initials: KS
authors.lastname: Kulkarni
authors.affiliation: Department of Psychiatry, Jagjivan Ram Hospital, Mumbai, Maharashtra, India.
authors.forename: M Ananthi K
authors.initials: MA
authors.lastname: Muthusamy
authors.affiliation: Department of Psychiatry, Jagjivan Ram Hospital, Mumbai, Maharashtra, India.
authors.forename: Malay D
authors.initials: MD
authors.lastname: Dave
keywords: Corpus callosum degeneration; Marchiafava Bignami disease in India; mahuwa alcohol