title: Metabolites of antroquinonol found in rat urine following oral administration.
abstract: Four metabolites (1-4) of antroquinonol from rat urine, collected within 24 h after oral administration of antroquinonol, were characterized by HPLC-SPE-NMR. Compounds 1-4 were further isolated by semipreparative HPLC for structure confirmation. Their structures were elucidated on the basis of 1D and 2D NMR spectroscopic analyses and HRESIMS data.
authors.affiliation: School of Pharmacy, College of Medicine, National Taiwan University , Taipei 10050, Taiwan, Republic of China.
authors.forename: Chien-Kuang
authors.initials: CK
authors.lastname: Chen
authors.forename: Jaw-Jou
authors.initials: JJ
authors.lastname: Kang
authors.forename: Wu-Che
authors.initials: WC
authors.lastname: Wen
authors.forename: Hui-Fen
authors.initials: HF
authors.lastname: Chiang
authors.forename: Shoei-Sheng
authors.initials: SS
authors.lastname: Lee
mesh_terms: D000284:Administration, Oral; D000818:Animals; D055491:Antrodia / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D008297:Male; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D051381:Rats; D017208:Rats, Wistar; D013237:Stereoisomerism; D014451:Ubiquinone / Q000031:analogs & derivatives* / Q000032:analysis / Q000494:pharmacology / Q000652:urine
chemical_list: D014451:Ubiquinone; C545357:antroquinonol