title: A simple method to prepare modified polyethersulfone membrane with improved hydrophilic surface by one-pot: The effect of hydrophobic segment length and molecular weight of copolymers.
abstract: A simple method to prepare modified polyethersulfone (PES) membrane by one-pot is provided, and the method includes three steps: polymerization of vinyl pyrrolidone (VP), copolymerization of methyl methacrylate (MMA) and blending with PES. The effect of the PMMA segment length and molecular weight of the copolymer (PVP-b-PMMA-b-PVP, as an additive) on the structures and properties of the modified membranes was investigated. Activated partial thromboplastin time (APTT) tests indicated that with the increase of the poly(methyl methacrylate) (PMMA) segment length in the chains of the copolymers and with the increase of the molecular weight of the copolymers, the APTTs of the modified membranes increased to some extent, since less of the additives were lost during liquid-liquid phase separation process. Therefore, the copolymer was designed and prepared with appropriate ratio of poly(vinyl pyrrolidone) (PVP) to MMA and with appropriate molecular weight for better membrane performance. When the copolymer was blended in the membrane, the water permeance, protein anti-fouling property and sieving coefficients for PEG-12000 increased obviously. The simple, credible and feasible method had the potential to be used for the modification of membranes with improved blood compatibility, ultrafiltration and antifouling properties of biomaterials and for practical production.
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, People's Republic of China; School of Material Science and Engineering, State Key Laboratory of Gansu Advanced Non-Ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, People's Republic of China. Electronic address: ranfen@163.com.
authors.forename: Fen
authors.initials: F
authors.lastname: Ran
authors.affiliation: School of Material Science and Engineering, State Key Laboratory of Gansu Advanced Non-Ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, People's Republic of China.
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, People's Republic of China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Lu
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, People's Republic of China.
authors.forename: Lingren
authors.initials: L
authors.lastname: Wang
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, People's Republic of China.
authors.forename: Shengqiang
authors.initials: S
authors.lastname: Nie
authors.affiliation: School of Material Science and Engineering, State Key Laboratory of Gansu Advanced Non-Ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, People's Republic of China.
authors.forename: Haiming
authors.initials: H
authors.lastname: Song
authors.affiliation: School of Material Science and Engineering, State Key Laboratory of Gansu Advanced Non-Ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, People's Republic of China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhao
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, People's Republic of China.
authors.forename: Shudong
authors.initials: S
authors.lastname: Sun
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, People's Republic of China. Electronic address: zhaochsh70@163.com.
authors.forename: Changsheng
authors.initials: C
authors.lastname: Zhao
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry / Q000494:pharmacology; D001777:Blood Coagulation / Q000187:drug effects; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D008567:Membranes, Artificial; D008970:Molecular Weight; D010314:Partial Thromboplastin Time; D011108:Polymers / Q000737:chemistry*; D019904:Polymethyl Methacrylate / Q000737:chemistry; D013450:Sulfones / Q000737:chemistry*; D013499:Surface Properties; D014462:Ultrafiltration
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011108:Polymers; D013450:Sulfones; C022840:polyether sulfone; D019904:Polymethyl Methacrylate
keywords: Amphiphilic triblock copolymer; Blood compatibility; One-pot; Polyethersulfone membrane