title: Management of third molar removal with doses of native plasma-derived factor IX (Octanine) and local measures in a female patient with severe hemophilia B: a case report.
abstract: Patients with hemophilia are at high risk of bleeding following oral surgery. As an X-linked recessive chromosomal bleeding disorder it is very rare in female patients. This is the first described case of management of third molar removal in a female patient suffering from severe hemophilia B. Excellent hemostasis was achieved by following a protocol using defined pre- and postoperative doses of factor IX and local hemostatic measures of collagen fleece, fibrin glue, primary suture, and tranexamic acid solution. Following defined protocols is essential in the management of oral surgery in patients with hemophilia and helps to prevent postoperative hemorrhages.
authors.forename: Andre
authors.initials: A
authors.lastname: Peisker
authors.forename: Karim
authors.initials: K
authors.lastname: Kentouche
authors.forename: Gregor Franziskus
authors.initials: GF
authors.lastname: Raschke
authors.forename: Stefan
authors.initials: S
authors.lastname: Schultze-Mosgau
mesh_terms: D005164:Factor IX / Q000627:therapeutic use*; D005260:Female; D002836:Hemophilia B / Q000150:complications*; D006489:Hemostatic Techniques; D006801:Humans; D008964:Molar, Third / Q000601:surgery*; D019106:Postoperative Hemorrhage / Q000517:prevention & control*; D014081:Tooth Extraction; D055815:Young Adult
chemical_list: D005164:Factor IX