title: α-Methyldopa-induced hepatitis during the postpartum period.
abstract: A 34-year-old woman, with a history of pre-eclampsia, was diagnosed with α-methyldopa-induced hepatotoxicity, after she presented with severe jaundice and hepatitis 8 weeks following delivery. Laboratory investigations and liver biopsy ruled out other causes of hepatitis. She continued to improve clinically after cessation of α-methyldopa, and was discharged 10 days after admission. This case report emphasises that it may not be possible to predict which patients may develop α-methyldopa-induced hepatitis, hence regular monitoring of liver function tests during treatment should be implemented.
authors.affiliation: Nepean Hospital, Sydney, New South Wales, Australia.
authors.forename: Soleiman
authors.initials: S
authors.lastname: Kashkooli
authors.forename: Brandon
authors.initials: B
authors.lastname: Baraty
authors.forename: Jamshid
authors.initials: J
authors.lastname: Kalantar
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008750:Methyldopa / Q000009:adverse effects*; D049590:Postpartum Period; D011225:Pre-Eclampsia / Q000188:drug therapy; D011247:Pregnancy
chemical_list: D000959:Antihypertensive Agents; D008750:Methyldopa