title: Restless legs syndrome is related to obstructive sleep apnea symptoms during pregnancy.
abstract: BACKGROUND
  To investigate the relation between restless legs syndrome (RLS) and obstructive sleep apnea symptoms during pregnancy.
  
  
  METHODS
  A questionnaire consisting of diagnostic criteria of restless legs syndrome, demographic characteristics, personal behavior, muscle cramps during pregnancy, past medical illnesses, family history of RLS, and the major symptoms of obstructive sleep apnea syndrome was administered during a face-to-face interview. Pregnant women with and without RLS were compared in terms of serum hemoglobin, hematocrit, calcium, phosphor, iron, folate, vitamin B12 levels, and obstructive sleep apnea symptoms.
  
  
  RESULTS
  There were statistically significant differences between two groups in terms of two of the obstructive sleep apnea symptoms (witnessed apnea and fatigue) (p < 0.01). No statistically significant difference was found with regard to serum calcium, magnesium, iron, hemoglobin, hematocrit, vitamin B12, phosphor, and folate levels; however, there were significant differences in terms of total iron-binding capacity.
  
  
  CONCLUSIONS
  Increasing awareness of restless legs syndrome among obstetricians is essential as it might be related to obstructive sleep apnea syndrome, which is associated with adverse pregnancy outcomes.
authors.affiliation: Department of Obstetrics and Gynecology, Derince Research and Training Hospital, Orhan mh. Devran cd. No:12, İzmit, Kocaeli, Turkey, drhterzi@yahoo.com.
authors.forename: Hasan
authors.initials: H
authors.lastname: Terzi
authors.forename: Rabia
authors.initials: R
authors.lastname: Terzi
authors.forename: Burak
authors.initials: B
authors.lastname: Zeybek
authors.forename: Mete
authors.initials: M
authors.lastname: Ergenoglu
authors.forename: Servet
authors.initials: S
authors.lastname: Hacivelioglu
authors.forename: Ali
authors.initials: A
authors.lastname: Akdemir
authors.forename: Ozgur
authors.initials: O
authors.lastname: Yeniel
mesh_terms: D000328:Adult; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D033862:Iron-Binding Proteins / Q000097:blood; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D012148:Restless Legs Syndrome / Q000175:diagnosis*; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis*
chemical_list: D033862:Iron-Binding Proteins