title: Carbohydrate-based Cu(I) stabilizing ligands and their use in the synthesis of carbohydrate-ferrocene conjugates.
abstract: A series of carbohydrate-ferrocene conjugates have been synthesized by copper(I)-catalyzed cycloaddition of carbohydrate-azides and ethynylferrocene (CuAAC). Newly carbohydrate-based tris-triazoles have been used as Cu(I) stabilizing ligands and showed at least comparable, in some cases even better results compared to the use of tris-(benzyltriazolylmethyl)amine (TBTA).
authors.affiliation: MCAT GmbH, Hermann-von-Vicari-Str. 23, 78464 Konstanz, Germany. Electronic address: schmidt@mcat.de.
authors.forename: Magnus S
authors.initials: MS
authors.lastname: Schmidt
authors.affiliation: Department of Chemistry, University of Konstanz, Germany. Electronic address: kim.leitner@uni-konstanz.de.
authors.forename: Kim
authors.initials: K
authors.lastname: Leitner
authors.affiliation: Department of Chemistry, University of Konstanz, Germany. Electronic address: moritz.welter@uni-konstanz.de.
authors.forename: Moritz
authors.initials: M
authors.lastname: Welter
authors.affiliation: Department of Chemistry, University of Konstanz, Germany. Electronic address: lena.wurmthaler@uni-konstanz.de.
authors.forename: Lena A
authors.initials: LA
authors.lastname: Wurmthaler
authors.affiliation: MCAT GmbH, Hermann-von-Vicari-Str. 23, 78464 Konstanz, Germany. Electronic address: ringwald@mcat.de.
authors.forename: Markus
authors.initials: M
authors.lastname: Ringwald
mesh_terms: D000480:Alkynes / Q000737:chemistry; D001386:Azides; D002241:Carbohydrates / Q000737:chemistry*; D002384:Catalysis; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry*; D005296:Ferrous Compounds / Q000737:chemistry*; D008024:Ligands; D000075163:Metallocenes; D015394:Molecular Structure; D014230:Triazoles / Q000737:chemistry
chemical_list: D000480:Alkynes; D001386:Azides; D002241:Carbohydrates; D005296:Ferrous Compounds; D008024:Ligands; D000075163:Metallocenes; D014230:Triazoles; D003300:Copper; C004998:ferrocene
keywords: Carbohydrates; Click chemistry; Cu(I) stabilizing ligands; Ferrocene; Glycoconjugates