title: Noninferiority trials: clinical understandings and misunderstandings.
authors.affiliation: SAIC in support of the Collaborative Clinical Research Branch, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), 6700B Rockledge Drive, Room 1123, Bethesda, MD 20892, USA.
authors.forename: John H
authors.initials: JH
authors.lastname: Powers
authors.affiliation: Department of Biostatistics, University of Washington, Box 357232, Seattle, WA, USA.
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Fleming
keywords: active control; informed consent; noninferiority margin; preservation of effect