title: A case of metastatic renal cell carcinoma treated effectively by gemcitabine and sunitinib.
abstract: A 60-year-old man with renal cell carcinoma developed lung metastases after treatment with left radical nephrectomy (pT3bN0M0, clear cell renal carcinoma, Fuhrman G3 >2). The patient received treatment with gemcitabine and interferon-α and achieved complete response after seven cycles of therapy. However, eight months later, local recurrence was discovered in the renal fossa. We changed the therapeutic strategy to sunitinib, a multi-target tyrosine kinase inhibitor. The patient achieved a complete response after twelve cycles of therapy. This case report illustrates the effective use of gemcitabine and sunitinib sequentially for a patient with metastatic renal cell carcinoma.
authors.affiliation: Division of Urology, Department of Surgery, Tottori University Faculty of Medicine, Tottori, Japan.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Morizane
authors.affiliation: Division of Urology, Department of Surgery, Tottori University Faculty of Medicine, Tottori, Japan.
authors.forename: Hideto
authors.initials: H
authors.lastname: Iwamoto
authors.affiliation: Division of Urology, Department of Surgery, Tottori University Faculty of Medicine, Tottori, Japan.
authors.forename: Akihisa
authors.initials: A
authors.lastname: Yao
authors.affiliation: Division of Urology, Department of Surgery, Tottori University Faculty of Medicine, Tottori, Japan.
authors.forename: Tadahiro
authors.initials: T
authors.lastname: Isoyama
authors.affiliation: Division of Urology, Department of Surgery, Tottori University Faculty of Medicine, Tottori, Japan.
authors.forename: Takehiro
authors.initials: T
authors.lastname: Sejima
authors.affiliation: Division of Urology, Department of Surgery, Tottori University Faculty of Medicine, Tottori, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takenaka
keywords: gemcitabine; metastatic renal cell carcinoma; sunitinib