title: Assessment of insulin resistance in non-diabetic hypertensives in Eastern India.
abstract: To assess prevalence of insulin resistance in non-diabetic hypertensive patients in eastern part of India, a case-control study was undertaken among 112 patients of hypertension without diabetes mellitus or ischaemic heart disease and 76 age and sex matched controls. Anthropometric measurements (height, weight, waist circumference) were done and fasting blood sugar and fasting insulin levels were estimated. Among 112 patients, 50.9% (n = 57) have fasting hyperinsulinaemia, whereas in control population 12% had hyperinsulinemia (p < 0.001). Mean waist circumference was higher in hypertensive patients compared to control. No statistical difference of body mass index between cases and control found. In this study prevalence of fasting hyperinsulinaemia, considered as a surrogate marker for insulin resistance, was 50% in hypertensives. Body mass index was not associated with insulin resistance or hypertension.
authors.affiliation: North Bengal Medical College, Sushrutanagar 734012.
authors.forename: Jyotirmoy
authors.initials: J
authors.lastname: Pal
authors.affiliation: North Bengal Medical College, Sushrutanagar 734012.
authors.forename: Ankit
authors.initials: A
authors.lastname: Shrivastav
authors.affiliation: Calcutta National Medical College, Kolkata 700014
authors.forename: Dipendranarayan
authors.initials: D
authors.lastname: Goswami
authors.affiliation: Calcutta National Medical College, Kolkata 700014
authors.forename: J D
authors.initials: JD
authors.lastname: Mukhopadhaya
authors.affiliation: Calcutta National Medical College, Kolkata 700014
authors.forename: P S
authors.initials: PS
authors.lastname: Karmakar
authors.affiliation: Calcutta National Medical College, Kolkata 700014
authors.forename: Pratim
authors.initials: P
authors.lastname: Sengupta
authors.affiliation: Calcutta National Medical College, Kolkata 700014
authors.forename: Suparna
authors.initials: S
authors.lastname: Chatterjee
authors.affiliation: NRS Medical College, Kolkata 700014.
authors.forename: N M
authors.initials: NM
authors.lastname: Biswas
mesh_terms: D001786:Blood Glucose / Q000378:metabolism*; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000453:epidemiology / Q000503:physiopathology; D007194:India / Q000453:epidemiology; D007328:Insulin / Q000097:blood*; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies
chemical_list: D001786:Blood Glucose; D007328:Insulin