title: [Bilateral diffuse uveal melanocytic proliferation in a patient with metastatic breast cancer].
abstract: A 64-year-old female patient with a history of metastatic breast cancer presented with bilateral deterioration of visual acuity over a period of several weeks. Examination revealed patchy fundus pigmentation, serous retinal detachment and cataract in both eyes. After diagnosis of a bilateral diffuse uveal melanocytic proliferation (BDUMP) and due to disease progression, a course of plasmapheresis three times a week over a period of 2 weeks was initiated. Apart from the occurrence of peripheral edemas the therapy was well-tolerated by the patient. Treatment success could not be evaluated because the patient died a short time later. This is the first reported case of BDUMP due to breast cancer.
authors.affiliation: Universitäts-Augenklinik Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Deutschland, alexandra.hoeh@med.uni-heidelberg.de.
authors.forename: A E
authors.initials: AE
authors.lastname: Höh
authors.forename: F G
authors.initials: FG
authors.lastname: Holz
authors.forename: S
authors.initials: S
authors.lastname: Dithmar
mesh_terms: D001943:Breast Neoplasms / Q000150:complications* / Q000556:secondary*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D059545:Paraneoplastic Syndromes, Ocular / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D010956:Plasmapheresis / Q000379:methods*; D016896:Treatment Outcome