title: T1 mapping in ischaemic heart disease.
abstract: A unique feature of cardiac magnetic resonance is its ability to characterize myocardium. Proton relaxation times, T1, T2, and T2* are a reflection of the composition of individual tissues, and change in the presence of disease. Research into T1 mapping has largely been focused in the study of cardiomyopathies, but T1 mapping also shows huge potential in the study of ischaemic heart disease. In fact, the first cardiac T1 maps were used to characterize myocardial infarction. Robust high-resolution myocardial T1 mapping is now available for use as a clinical tool. This quantitative technique is simple to perform and analyse, minimally subjective, and highly reproducible. This review aims to summarize the present state of research on the topic, and to show the clinical potential of this method to aid the diagnosis and treatment of patients with ischaemic heart disease.
authors.affiliation: Department of Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, Germany Division of Imaging Sciences and Biomedical Engineering, St Thomas' Hospital, 4th Floor, Lambeth Wing, Westminster Bridge Road, London SE1 7EH, UK darachohici@gmail.com.
authors.forename: Darach O
authors.initials: DO
authors.lastname: h-Ici
authors.affiliation: Department of Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, Germany.
authors.forename: Sarah
authors.initials: S
authors.lastname: Jeuthe
authors.affiliation: Department of Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, Germany.
authors.forename: Nadya
authors.initials: N
authors.lastname: Al-Wakeel
authors.affiliation: Department of Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, Germany.
authors.forename: Felix
authors.initials: F
authors.lastname: Berger
authors.affiliation: Department of Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, Germany.
authors.forename: Titus
authors.initials: T
authors.lastname: Kuehne
authors.affiliation: Division of Imaging Sciences and Biomedical Engineering, St Thomas' Hospital, 4th Floor, Lambeth Wing, Westminster Bridge Road, London SE1 7EH, UK Institute for Biomedical Engineering, University and ETH Zurich, Gloriastrasse 35, Zürich 8092, Switzerland.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Kozerke
authors.affiliation: Department of Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, Germany Department of Internal Medicine/Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, Germany.
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Messroghli
mesh_terms: D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis; D017202:Myocardial Ischemia / Q000175:diagnosis*; D012680:Sensitivity and Specificity
chemical_list: D019786:Gadolinium DTPA
keywords: ECV; Ischaemic heart disease; Myocardial infarction; Myocardial ischaemia; T1 Mapping