title: Mycobacterium szulgai chronic multifocal osteomyelitis in an adolescent with inherited STAT1 deficiency.
abstract: We report a 17-year-old patient with inherited STAT1 deficiency, who was diagnosed with Mycobacterium szulgai chronic multifocal osteomyelitis and responded well to the therapy with ethambutol, rifampicin and azithromycin. Seven other reported cases of M. szulgai osteomyelitis are reviewed. This is the first description of M. szulgai osteomyelitis in an adolescent with a primary immunodeficiency.
authors.affiliation: From the *Department of Pediatrics; †Pediatric Infectious Diseases Unit, Hadassah-Hebrew University Medical Center, Ein Kerem, Jerusalem, Israel; ‡School of Primary Health Care, Monash University, Melbourne, Victoria, Australia; §Department of Microbiology, Hadassah-Hebrew University Medical Center, Ein Kerem, Jerusalem; ¶National Mycobacterium Reference Laboratory, National Public Health Laboratory, Ministry of Health, Tel Aviv, Israel; and ‖St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, NY.
authors.forename: Oded
authors.initials: O
authors.lastname: Shamriz
authors.forename: Dan
authors.initials: D
authors.lastname: Engelhard
authors.forename: Andrea Psorn
authors.initials: AP
authors.lastname: Rajs
authors.forename: Hasia
authors.initials: H
authors.lastname: Kaidar-Shwartz
authors.forename: Jean-Laurent
authors.initials: JL
authors.lastname: Casanova
authors.forename: Diana
authors.initials: D
authors.lastname: Averbuch
mesh_terms: D000293:Adolescent; D000904:Antibiotics, Antitubercular / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009165:Mycobacterium Infections, Nontuberculous / Q000235:genetics / Q000378:metabolism* / Q000382:microbiology; D009170:Nontuberculous Mycobacteria / Q000187:drug effects / Q000302:isolation & purification*; D010019:Osteomyelitis / Q000235:genetics / Q000378:metabolism* / Q000382:microbiology*; D050794:STAT1 Transcription Factor / Q000172:deficiency* / Q000235:genetics
chemical_list: D000904:Antibiotics, Antitubercular; D050794:STAT1 Transcription Factor; C494079:STAT1 protein, human