title: Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA.
abstract: The 24th Antibody Engineering & Therapeutics meeting brought together a broad range of participants who were updated on the latest advances in antibody research and development. Organized by IBC Life Sciences, the gathering is the annual meeting of The Antibody Society, which serves as the scientific sponsor. Preconference workshops on 3D modeling and delineation of clonal lineages were featured, and the conference included sessions on a wide variety of topics relevant to researchers, including systems biology; antibody deep sequencing and repertoires; the effects of antibody gene variation and usage on antibody response; directed evolution; knowledge-based design; antibodies in a complex environment; polyreactive antibodies and polyspecificity; the interface between antibody therapy and cellular immunity in cancer; antibodies in cardiometabolic medicine; antibody pharmacokinetics, distribution and off-target toxicity; optimizing antibody formats for immunotherapy; polyclonals, oligoclonals and bispecifics; antibody discovery platforms; and antibody-drug conjugates.
authors.affiliation: CTI-Boston, Pfizer; Boston, MA USA.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Almagro
authors.affiliation: Janssen Research & Development, LLC; Spring House, PA USA.
authors.forename: Gary L
authors.initials: GL
authors.lastname: Gilliland
authors.affiliation: Simon Fraser University; Burnaby, BC CA.
authors.forename: Felix
authors.initials: F
authors.lastname: Breden
authors.affiliation: Simon Fraser University; Burnaby, BC CA.
authors.forename: Jamie K
authors.initials: JK
authors.lastname: Scott
authors.affiliation: The Scripps Research Institute; La Jolla, CA USA.
authors.forename: Devin
authors.initials: D
authors.lastname: Sok
authors.affiliation: The Scripps Research Institute; La Jolla, CA USA.
authors.forename: Matthias
authors.initials: M
authors.lastname: Pauthner
authors.affiliation: Reichert Biotechnology Consulting, LLC; Framingham, MA USA.
authors.forename: Janice M
authors.initials: JM
authors.lastname: Reichert
authors.affiliation: CONICET; Laboratorio Biotecnología Farmacéutica; Instituto de Biología y Medicina Experimental, IBYME; Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Helguera
authors.affiliation: The Scripps Research Institute; La Jolla, CA USA.
authors.forename: Raiees
authors.initials: R
authors.lastname: Andrabi
authors.affiliation: Adimab, LLC; Lebanon, NH USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Mabry
authors.affiliation: Innate Pharma; Marseille, France.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Bléry
authors.affiliation: The Scripps Research Institute; La Jolla, CA USA.
authors.forename: James E
authors.initials: JE
authors.lastname: Voss
authors.affiliation: Regeneron Pharmaceuticals, Inc.; Tarrytown, NY USA.
authors.forename: Juha
authors.initials: J
authors.lastname: Laurén
authors.affiliation: Amgen, Thousand Oaks, CA, USA.
authors.forename: Lubna
authors.initials: L
authors.lastname: Abuqayyas
authors.affiliation: AbbVie; Ludwigshafen, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Barghorn
authors.affiliation: Tel Aviv University, Tel Aviv, Israel.
authors.forename: Eshel
authors.initials: E
authors.lastname: Ben-Jacob
authors.affiliation: Vanderbilt University Medical Center, Nashville, TN, USA.
authors.forename: James E
authors.initials: JE
authors.lastname: Crowe
authors.affiliation: Huston BioConsulting, LLC; Newton, MA, USA.
authors.forename: James S
authors.initials: JS
authors.lastname: Huston
authors.affiliation: Arizona State University; Phoenix, AZ USA.
authors.forename: Stephen Albert
authors.initials: SA
authors.lastname: Johnston
authors.affiliation: Adimab, LLC; Lebanon, NH USA.
authors.forename: Eric
authors.initials: E
authors.lastname: Krauland
authors.affiliation: Oslo University Hospital; Oslo, Norway.
authors.forename: Fridtjof
authors.initials: F
authors.lastname: Lund-Johansen
authors.affiliation: Dana-Farber Cancer Center; Boston, MA USA.
authors.forename: Wayne A
authors.initials: WA
authors.lastname: Marasco
authors.affiliation: Genmab; Utrecht, The Netherlands.
authors.forename: Paul W H I
authors.initials: PW
authors.lastname: Parren
authors.affiliation: University of Maryland; Baltimore, MD USA.
authors.forename: Kai Y
authors.initials: KY
authors.lastname: Xu
mesh_terms: D000818:Animals; D000906:Antibodies / Q000737:chemistry* / Q000235:genetics / Q000627:therapeutic use*; D019020:Directed Molecular Evolution; D015195:Drug Design; D006801:Humans; D007167:Immunotherapy; D009369:Neoplasms / Q000628:therapy; D015202:Protein Engineering; D012958:Societies, Scientific; D049490:Systems Biology
chemical_list: D000906:Antibodies
keywords: antibody therapeutics,; antibody-drug conjugate; bispecific antibodies; protein scaffolds