title: [Identification of benzoic acid, sorbic aicid and dehydroacetic acid residues in alcoholic drinks and beverages].
abstract: OBJECTIVE
  To establish a qualitative system for the identification of benzoic acid, sorbic acid and dehydroacetic acid residues in alcoholic drinks and beverages by ultra-fast liquid chromatography coupled with electrospray ionization tandem mass spectrometry (UFLC/ESI-MS/MS).
  
  
  METHODS
  After the sample was extracted, the separation was performed by UFLC and the cracking was used by the optimized ESI-MS/ MS conditions. Confirmatory detection was carried out by the principle of three qualitative ions and retention time using an UFLC-MS/MS in the negative electrospray ionization mode.
  
  
  RESULTS
  The MS/MS fragment ions were reliable and steady under the suitable conditions, the cracking ways to the parent ions and fragment ions were clear. Qualitative ion pairs were m/z 121-->77 and m/z 121-->59 for benzoic acid, m/z 111-->67 and m/z 111-->41 for sorbic acid, m/z 167-->83 and m/z 167-->123 for dehydroacetic acid. The limits of quantitation (LOQs) were 0.02, 0.05 and 0.02 mg/L for benzoic acid, sorbic acid and dehydroacetic acid, respectively.
  
  
  CONCLUSIONS
  The established method was rapid, accurate and sensitive, it is suitable for confirmation for benzoic acid, sorbic acid and dehydroacetic acid residues in alcoholic drinks and beverages.
authors.affiliation: Medical School, Ningbo University, Ningbo 315211, China. zhuhao@163.com
authors.forename: Hao
authors.initials: H
authors.lastname: Zhu
authors.affiliation: Medical School, Ningbo University, Ningbo 315211, China.
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Chen
authors.affiliation: Medical School, Ningbo University, Ningbo 315211, China.
authors.forename: Yonggang
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Medical School, Ningbo University, Ningbo 315211, China.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Li
authors.affiliation: Medical School, Ningbo University, Ningbo 315211, China.
authors.forename: Shengdong
authors.initials: S
authors.lastname: Pan
authors.affiliation: Medical School, Ningbo University, Ningbo 315211, China.
authors.forename: Micong
authors.initials: M
authors.lastname: Jin
mesh_terms: D000434:Alcoholic Beverages / Q000032:analysis*; D019817:Benzoic Acid / Q000032:analysis*; D001628:Beverages / Q000032:analysis*; D002853:Chromatography, Liquid; D011753:Pyrones / Q000032:analysis*; D013011:Sorbic Acid / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization; D053719:Tandem Mass Spectrometry
chemical_list: D011753:Pyrones; C027493:dehydroacetic acid; D019817:Benzoic Acid; D013011:Sorbic Acid