title: Perspective of humanized mouse models for assessing PK/PD and toxic profile of drug candidates in preclinical study.
authors.affiliation: President of the JSSX.
authors.forename: Kan
authors.initials: K
authors.lastname: Chiba
mesh_terms: D000818:Animals; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D064420:Drug-Related Side Effects and Adverse Reactions / Q000378:metabolism*; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D023421:Models, Animal; D010599:Pharmacokinetics; D018675:Toxicity Tests / Q000379:methods