title: 3D intraventricular flow mapping from colour Doppler images and wall motion.
abstract: We propose a new method to recover 3D time-resolved velocity vectors within the left ventricle (LV) using a combination of multiple registered 3D colour Doppler images and LV wall motion. Incorporation of wall motion, calculated from 3D B-Mode images, and the use of a multi-scale reconstruction framework allow recovery of 3D velocity over the entire ventricle, even in regions where there is little or no Doppler data. Our method is tested on the LV of a paediatric patient and is compared to 2D and 3D flow Magnetic Resonance Imaging (MRI). Use of wall motion information increased stroke volume accuracy by 14%, and enabled full 3D velocity mapping within the ventricle. Velocity distribution showed good agreement with respect to MRI, and vortex formation during diastole was successfully reconstructed.
authors.affiliation: King's College London, Division of Imaging Sciences, London, UK.
authors.forename: Alberto
authors.initials: A
authors.lastname: Gómez
authors.affiliation: King's College London, Division of Imaging Sciences, London, UK.
authors.forename: Adelaide
authors.initials: A
authors.lastname: de Vecchi
authors.affiliation: King's College London, Division of Imaging Sciences, London, UK.
authors.forename: Kuberan
authors.initials: K
authors.lastname: Pushparajah
authors.affiliation: King's College London, Division of Imaging Sciences, London, UK.
authors.forename: John
authors.initials: J
authors.lastname: Simpson
authors.affiliation: King's College London, Division of Imaging Sciences, London, UK.
authors.forename: Daniel
authors.initials: D
authors.lastname: Giese
authors.affiliation: King's College London, Division of Imaging Sciences, London, UK.
authors.forename: Tobias
authors.initials: T
authors.lastname: Schaeffter
authors.affiliation: King's College London, Division of Imaging Sciences, London, UK.
authors.forename: Graeme
authors.initials: G
authors.lastname: Penney
mesh_terms: D000465:Algorithms; D018618:Echocardiography, Doppler, Color / Q000379:methods*; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007223:Infant; D008297:Male; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique