title: NAFLD. Metabolic make-up of NASH: from fat and sugar to amino acids.
abstract: NAFLD is regarded unquestionably as one of the components of the metabolic syndrome. Hence, metabolic perturbations occurring in the fatty liver become a systemic metabolic derangement. The phenotypic switching from fatty liver to NASH entails a reprogramming of liver metabolism to fit a stressful metabolic environment.
authors.affiliation: Department of Clinical and Molecular Hepatology, Institute of Medical Research A Lanari-IDIM, University of Buenos Aires-National Scientific and Technical Research Council (CONICET), Combatiente de Malvinas 3150, Ciudad Autónoma de Buenos Aires 1427, Argentina.
authors.forename: Silvia
authors.initials: S
authors.lastname: Sookoian
authors.affiliation: Department of Molecular Genetics and Biology of Complex Diseases, Institute of Medical Research A Lanari-IDIM, University of Buenos Aires-National Scientific and Technical Research Council (CONICET), Combatiente de Malvinas 3150, Ciudad Autónoma de Buenos Aires 1427, Argentina.
authors.forename: Carlos J
authors.initials: CJ
authors.lastname: Pirola
mesh_terms: D005260:Female; D016678:Genome / Q000235:genetics*; D022781:Hepatocytes / Q000378:metabolism*; D006801:Humans; D008297:Male; D008954:Models, Biological; D008957:Models, Genetic; D065626:Non-alcoholic Fatty Liver Disease / Q000235:genetics* / Q000378:metabolism*; D012694:Serine / Q000172:deficiency*
chemical_list: D012694:Serine