title: Diversity-oriented synthesis of ketoindoloquinoxalines and indolotriazoloquinoxalines from 1-(2-nitroaryl)-2-alkynylindoles.
abstract: A one-pot protocol for the diversity-oriented synthesis of two indole-based annulated polyheterocycles, ketoindoloquinoxalines and indolotriazoloquinoxalines, has been described. The salient features of the methodology involves either a metal/O2-catalyzed aminooxygenation or a [3 + 2] cycloaddition pathway.
authors.affiliation: Medicinal and Process Chemistry Division and ‡Molecular and Structural Biology Division, CSIR-Central Drug Research Institute , B.S. 10/1, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226001, India.
authors.forename: Srinivas
authors.initials: S
authors.lastname: Samala
authors.forename: Rajesh K
authors.initials: RK
authors.lastname: Arigela
authors.forename: Ruchir
authors.initials: R
authors.lastname: Kant
authors.forename: Bijoy
authors.initials: B
authors.lastname: Kundu
mesh_terms: D002384:Catalysis; D061565:Cycloaddition Reaction; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000737:chemistry*; D011810:Quinoxalines / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D006576:Heterocyclic Compounds, 4 or More Rings; D007211:Indoles; D011810:Quinoxalines