title: Diabetes in older people: Prevalence, incidence and its association with medium- and long-term mortality from all causes.
abstract: OBJECTIVE
  To estimate the prevalence and incidence of self-reported diabetes and to study its association with medium- and long-term mortality from all causes in persons ≥ 65 years.
  
  
  METHODS
  A population-based cohort study begun in 1993.
  
  
  METHODS
  "Envejecer en Leganés" cohort (Madrid).
  
  
  METHODS
  A random sample of persons ≥ 65 years (n=1277 in the 1993 baseline sample).
  
  
  METHODS
  Participants were classified as having diabetes if they so reported and had consulted a physician for this reason within the last year. Diabetes history was categorized in <10 and ≥ 10 years in 1993. Incidence density was calculated in 2-year periods in non-diabetic individuals (1965 persons/2 years). Vital status was recorded on 31 December 2011. The association between diabetes history ≥ 10 years and mortality at 6 and 18 years follow-up was studied by the Kaplan-Meier and Cox regression analyses after adjusting for age, sex, heart disease and comorbidity.
  
  
  RESULTS
  The prevalence of self-reported diabetes rose from 10.3% in 1993 to 16.1% in 1999 (p ≤ 0.001) and was higher in women than men (p ≤ 0.05). Total incidence density was 2.6 cases/100 persons/2 years (95% CI: 2.0-3.3). Medium- and long-term mortality was higher in persons with diabetes history ≥ 10 years than in non-diabetic individuals (HR: 2.0; 95% CI: 1.2-3.3 and HR: 1.7; 95% CI: 1.1-2.5, respectively). In diabetics with history <10 years the HR was 1.3 (95% CI: 0.9-1.9) and HR: 1.5 (95% CI: 1.2-1.9, respectively).
  
  
  CONCLUSIONS
  Although diabetes is clearly associated with increased risk of mortality, it is significant only for patients with ≥ 10 years' history of diabetes.
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Universidad Autónoma de Madrid, Madrid, Spain; IdiPAZ, Instituto de Investigación Hospital La Paz, Madrid, Spain. Electronic address: mercedes.martinez@uam.es.
authors.forename: Mercedes
authors.initials: M
authors.lastname: Sánchez Martínez
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Universidad Autónoma de Madrid, Madrid, Spain; Centro de Salud Reina Victoria, Madrid, Spain.
authors.forename: Augusto
authors.initials: A
authors.lastname: Blanco
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Universidad Autónoma de Madrid, Madrid, Spain; Centro de Salud Dr. Castroviejo, Madrid, Spain; IdiPAZ, Instituto de Investigación Hospital La Paz, Madrid, Spain.
authors.forename: María Victoria
authors.initials: MV
authors.lastname: Castell
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Universidad Autónoma de Madrid, Madrid, Spain.
authors.forename: Alicia
authors.initials: A
authors.lastname: Gutiérrez Misis
authors.affiliation: Servicio de Geriatría, Hospital Universitario La Paz, Madrid, Spain; IdiPAZ, Instituto de Investigación Hospital La Paz, Madrid, Spain.
authors.forename: Juan Ignacio
authors.initials: JI
authors.lastname: González Montalvo
authors.affiliation: Département de Médecine Sociale et Préventive, Université de Montréal, Québec, Canada.
authors.forename: María Victoria
authors.initials: MV
authors.lastname: Zunzunegui
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Universidad Autónoma de Madrid, Madrid, Spain; IdiPAZ, Instituto de Investigación Hospital La Paz, Madrid, Spain.
authors.forename: Ángel
authors.initials: Á
authors.lastname: Otero
mesh_terms: D000368:Aged; D002423:Cause of Death; D015331:Cohort Studies; D003920:Diabetes Mellitus / Q000453:epidemiology* / Q000401:mortality; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D015995:Prevalence; D013997:Time Factors
keywords: Cohort studies; Diabetes; Elderly; Estudios de cohortes; Incidence; Incidencia; Mayores; Mortalidad; Mortality; Prevalence; Prevalencia