title: Sex differences in the developmental origins of cardiovascular disease.
abstract: The Developmental Origins of Health and Disease (DOHaD) proposes that adverse events during early life program an increased risk for cardiovascular disease. Experimental models provide proof of concept but also indicate that insults during early life program sex differences in adult blood pressure and cardiovascular risk. This review will highlight the potential mechanisms that contribute to the etiology of sex differences in the developmental programming of cardiovascular disease.
authors.affiliation: Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi;
authors.forename: Suttira
authors.initials: S
authors.lastname: Intapad
authors.forename: Norma B
authors.initials: NB
authors.lastname: Ojeda
authors.forename: John Henry
authors.initials: JH
authors.lastname: Dasinger
authors.forename: Barbara T
authors.initials: BT
authors.lastname: Alexander
mesh_terms: D000818:Animals; D001724:Birth Weight / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D002318:Cardiovascular Diseases / Q000209:etiology*; D006801:Humans; D007668:Kidney / Q000502:physiology; D012307:Risk Factors; D012727:Sex Characteristics