title: [Leuko-glycemic index as an in-hospital prognostic marker in patients with ST-segment elevation myocardial infarction].
abstract: BACKGROUND
  Blood glucose and white blood cell count on admission have demonstrated prognostic significance in patients with myocardial infarction; leuko-glycemic index, a recently proposed marker, still lacks enough knowledge about its value.
  
  
  OBJECTIVE
  To evaluate the leuko-glycemic index as a prognostic marker in patients with ST-segment elevation myocardial infarction.
  
  
  METHODS
  A retrospective study was carried out in 128 patients with ST-segment elevation myocardial infarction, who were admitted between January 2009 and October 2010 in the Intensive Care Unit of the Hospital Dr. Celestino Hernández Robau. Clinical and laboratory data were collected, including glucose and white blood cell count on admission, from which we calculated the leuko-glycemic index and we evaluated its prognostic value.
  
  
  RESULTS
  Patients who had a poor outcome such as death, major cardiac complications and failed-thrombolysis, showed higher values of leuko-glycemic index (P<.01), which was correlated with several variables such as Killip class, and heart rate on admission (P=.000). We obtained a cutoff point of 1.158, patients with higher values had 3 times higher probability of death and complications (odds ratio=3,0; IC 95%: 1,2-7,3; P=.005); so leuko-glycemic index was an independent predictor after multivariate analysis.
  
  
  CONCLUSIONS
  The leuko-glycemic index was associated with an increased occurrence of hospital complications, death and failed-thrombolysis; its pathological value was an independent predictor of in-hospital death and complications in the studied sample.
authors.affiliation: Servicio de Cardiología, Hospital Dr. Celestino Hernández Robau, Villa Clara, Cuba.
authors.forename: Ebrey
authors.initials: E
authors.lastname: León-Aliz
authors.affiliation: Unidad de Hemodinámica y Cardiología Intervencionista, Cardiocentro Ernesto Che Guevara, Villa Clara, Cuba. Electronic address: flmorenom@yahoo.com.
authors.forename: Francisco L
authors.initials: FL
authors.lastname: Moreno-Martínez
authors.affiliation: Servicio de Cardiología, Hospital Dr. Celestino Hernández Robau, Villa Clara, Cuba.
authors.forename: Guillermo A
authors.initials: GA
authors.lastname: Pérez-Fernández
authors.affiliation: Unidad de Hemodinámica y Cardiología Intervencionista, Cardiocentro Ernesto Che Guevara, Villa Clara, Cuba.
authors.forename: Luis F
authors.initials: LF
authors.lastname: Vega-Fleites
authors.affiliation: Centro de Medicina Deportiva, Villa Clara, Cuba.
authors.forename: Magda A
authors.initials: MA
authors.lastname: Rabassa-López-Calleja
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000378:metabolism; D001786:Blood Glucose / Q000502:physiology*; D005260:Female; D038321:Glycemic Index / Q000502:physiology*; D006760:Hospitalization; D006801:Humans; D007362:Intensive Care Units; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology*; D011379:Prognosis; D012189:Retrospective Studies
chemical_list: D015415:Biomarkers; D001786:Blood Glucose
keywords: Infarto de miocardio; Leuko-glycemic index; Myocardial infarction; Prognosis; Pronóstico; Índice leuco-glucémico