title: An adolescent with a rare midline neck tumor: thyroid carcinoma in a thyroglossal duct cyst.
abstract: Occurrence of malignancy in a thyroglossal duct cyst (TDC) in children and adolescents is very rare, preoperative diagnosis is a challenge, and appropriate management is still debated. We report a 19-year-old male patient referred for a midline neck mass diagnosed as an atypical TDC after initial and subsequent investigations. Ultrasound-guided fine-needle aspiration (FNA) of the mass was diagnostic for papillary thyroid carcinoma. Sistrunk procedure and total thyroidectomy were performed. Histologic analysis confirmed the presence of papillary thyroid carcinoma within TDC, infiltrating surrounding soft tissues. Postoperatively, radioiodine ablation treatment was administered, followed by TSH suppression therapy.
authors.affiliation: *Endocrine Unit §2nd Department of Internal Medicine-Propaedeutic †2nd Department of Otorhinolaryngology ‡Department of Cytopathology, Athens University Medical School, "Attikon" University Hospital, Athens, Greece.
authors.forename: Evangeline
authors.initials: E
authors.lastname: Vassilatou
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Proikas
authors.forename: Niki
authors.initials: N
authors.lastname: Margari
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Papadimitriou
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Hadjidakis
authors.forename: George
authors.initials: G
authors.lastname: Dimitriadis
mesh_terms: D000293:Adolescent; D044963:Biopsy, Fine-Needle; D002291:Carcinoma, Papillary / Q000175:diagnosis* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D011379:Prognosis; D013955:Thyroglossal Cyst / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000628:therapy; D014463:Ultrasonography; D055815:Young Adult