title: [From prion diseases to Alzheimer's disease: a common therapeutic target, PDK1].
authors.affiliation: Université Paris Descartes, Inserm UMR-S 747, Sorbonne Paris Cité, 45, rue des Saints-Pères, 75006 Paris, France.
authors.forename: Mathéa
authors.initials: M
authors.lastname: Pietri
authors.affiliation: Université Paris Descartes, Inserm UMR-S 747, Sorbonne Paris Cité, 45, rue des Saints-Pères, 75006 Paris, France.
authors.forename: Aurélie
authors.initials: A
authors.lastname: Alleaume-Butaux
authors.affiliation: AP-HP, service de biochimie, Inserm UMR-S 942, 45, rue des Saints-Pères, 75006 Paris, France - Pharma research department, Hoffmann La Roche, Bâle, Suisse.
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Launay
authors.affiliation: Université Paris Descartes, Inserm UMR-S 747, Sorbonne Paris Cité, 45, rue des Saints-Pères, 75006 Paris, France.
authors.forename: Odile
authors.initials: O
authors.lastname: Kellermann
authors.affiliation: Université Paris Descartes, Inserm UMR-S 747, Sorbonne Paris Cité, 45, rue des Saints-Pères, 75006 Paris, France.
authors.forename: Benoit
authors.initials: B
authors.lastname: Schneider
mesh_terms: D051722:ADAM Proteins / Q000378:metabolism; D000072198:ADAM17 Protein; D000544:Alzheimer Disease / Q000201:enzymology*; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006801:Humans; D017096:Prion Diseases / Q000201:enzymology*; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors / Q000502:physiology*; D000081382:Pyruvate Dehydrogenase Acetyl-Transferring Kinase
chemical_list: D004791:Enzyme Inhibitors; C000631429:PDK1 protein, human; D000081382:Pyruvate Dehydrogenase Acetyl-Transferring Kinase; D017346:Protein Serine-Threonine Kinases; D051722:ADAM Proteins; D000072198:ADAM17 Protein