title: The BBX family of plant transcription factors.
abstract: The B-box (BBX) proteins are a class of zinc-finger transcription factors containing a B-box domain with one or two B-box motifs, and sometimes also feature a CCT (CONSTANS, CO-like, and TOC1) domain. BBX proteins are key factors in regulatory networks controlling growth and developmental processes that include seedling photomorphogenesis, photoperiodic regulation of flowering, shade avoidance, and responses to biotic and abiotic stresses. In this review we discuss the functions of BBX proteins and the role of B-box motif in mediating transcriptional regulation and protein-protein interaction in plant signaling. In addition, we provide novel insights into the molecular mechanisms of their action and the evolutionary significance of their functional divergence.
authors.affiliation: Department of Biological and Environmental Sciences, Gothenburg University, Gothenburg 40530, Sweden.
authors.forename: Sreeramaiah N
authors.initials: SN
authors.lastname: Gangappa
authors.affiliation: Instituto de Investigaciones Fisiológicas y Ecológicas Vinculadas a la Agricultura, Facultad de Agronomía, Universidad de Buenos Aires y Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1417, Argentina. Electronic address: botto@agro.uba.ar.
authors.forename: Javier F
authors.initials: JF
authors.lastname: Botto
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000502:physiology / Q000528:radiation effects; D029681:Arabidopsis Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D019143:Evolution, Molecular; D035264:Flowers / Q000235:genetics / Q000502:physiology / Q000528:radiation effects; D018506:Gene Expression Regulation, Plant; D008027:Light; D017440:Photoperiod; D010937:Plant Growth Regulators / Q000378:metabolism; D017434:Protein Structure, Tertiary; D036226:Seedlings / Q000235:genetics / Q000502:physiology / Q000528:radiation effects; D015398:Signal Transduction; D013312:Stress, Physiological; D014157:Transcription Factors / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D016335:Zinc Fingers
chemical_list: D029681:Arabidopsis Proteins; D010937:Plant Growth Regulators; D014157:Transcription Factors
keywords: Arabidopsis; B-box (BBX) protein; development; functional diversity; growth; transcription factors