title: Stochastic demography and the neutral substitution rate in class-structured populations.
abstract: The neutral rate of allelic substitution is analyzed for a class-structured population subject to a stationary stochastic demographic process. The substitution rate is shown to be generally equal to the effective mutation rate, and under overlapping generations it can be expressed as the effective mutation rate in newborns when measured in units of average generation time. With uniform mutation rate across classes the substitution rate reduces to the mutation rate.
authors.affiliation: Department of Ecology and Evolution, University of Lausanne, Sorge, Le Biophore, CH -1015 Lausanne, Switzerland.
authors.forename: Laurent
authors.initials: L
authors.lastname: Lehmann
mesh_terms: D000483:Alleles; D003710:Demography; D005828:Genetics, Population; D006801:Humans; D008957:Models, Genetic; D059645:Mutation Rate; D013269:Stochastic Processes
keywords: effective mutation rate; generation time; reproductive value; stochastic demography; substitution rate