title: Kawasaki disease in a girl with Turner syndrome: a remarkable association.
abstract: We describe a girl with Turner syndrome, a genetic disorder of the X chromosome in a phenotypic female at increased risk of autoimmune and immunological diseases, who developed Kawasaki disease at the age of four years. Given the possible relationship between these two disorders, we recommend suspecting Kawasaki disease in patients with Turner syndrome who present with persistent fever of unknown origin and who are not responsive to antibiotic therapy. Attention should be given to this phenomenon, as patients with Turner syndrome are themselves at higher risk of cardiovascular defects. Further studies are needed to better clarify this issue.
authors.affiliation: Department of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy. stefano.stagi@yahoo.it.
authors.forename: Stefano
authors.initials: S
authors.lastname: Stagi
authors.forename: Stefania
authors.initials: S
authors.lastname: Losi
authors.forename: Francesco
authors.initials: F
authors.lastname: Chiarelli
authors.forename: Maurizio
authors.initials: M
authors.lastname: de Martino
authors.forename: Fernanda
authors.initials: F
authors.lastname: Falcini
mesh_terms: D015551:Autoimmunity; D002675:Child, Preschool; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009080:Mucocutaneous Lymph Node Syndrome / Q000209:etiology* / Q000276:immunology; D010641:Phenotype; D012307:Risk Factors; D014424:Turner Syndrome / Q000150:complications* / Q000235:genetics