title: Cardiac restriction secondary to massive calcific deposits in the left ventricular cavity.
abstract: Described herein are clinical and necropsy findings in a 61-year-old woman with fatal left ventricular diastolic failure secondary to massive calcific deposits primarily within the left ventricular cavity. At age 3, an isthmic aortic coarctation was resected, and at age 44, a stenotic congenitally bicuspid aortic valve was replaced. The cause of the intracavitary calcific deposits remains unclear, but surgical resection of the deposits has been an effective form of therapy.
authors.affiliation: Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, Texas; Department of Pathology, Baylor University Medical Center, Dallas, Texas; Division of Cardiology, Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas. Electronic address: wc.roberts@baylorhealth.edu.
authors.forename: William C
authors.initials: WC
authors.lastname: Roberts
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas.
authors.forename: Randall L
authors.initials: RL
authors.lastname: Rosenblatt
authors.affiliation: Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, Texas.
authors.forename: Jong Mi
authors.initials: JM
authors.lastname: Ko
authors.affiliation: Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, Texas; Division of Cardiology, Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas.
authors.forename: Paul A
authors.initials: PA
authors.lastname: Grayburn
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas.
authors.forename: Johannes J
authors.initials: JJ
authors.lastname: Kuiper
authors.affiliation: Department of Pathology, Baylor University Medical Center, Dallas, Texas.
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Guileyardo
mesh_terms: D002114:Calcinosis / Q000150:complications* / Q000175:diagnosis; D009202:Cardiomyopathies / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D004452:Echocardiography; D017809:Fatal Outcome; D005260:Female; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology*; D006352:Heart Ventricles; D006801:Humans; D008875:Middle Aged; D013902:Radiography, Thoracic; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D018487:Ventricular Dysfunction, Left / Q000150:complications* / Q000175:diagnosis