title: Suspected Lythrum hyssopifolia (lesser loosestrife) poisoning of cattle.
abstract: METHODS
  Morbidity and mortality in two herds of cattle in southern New South Wales were associated with ingestion of lesser or hyssop loosestrife (Lythrum hyssopifolia). Clinical signs in adult cows included depression, listlessness, inappetence, anorexia and recumbency. Deaths occurred in 16/48 (33.3%) and 4/60 (6.7%) adult cows, but calves in both herds were unaffected. Elevated concentrations of urea and creatinine were present in the serum of one clinically affected cow and an elevated concentration of urea was detected in the aqueous humour of one cow that died. On histopathological examination, there was severe, acute necrosis of the proximal convoluted tubular epithelial cells in the kidneys of both affected cattle examined.
  
  
  CONCLUSIONS
  There is strong evidence that lesser loosestrife is nephrotoxic for cattle.
authors.affiliation: Elizabeth Macarthur Agricultural Institute, State Veterinary Diagnostic Laboratory, NSW Primary Industries, Menangle, New South Wales, Australia.
authors.forename: J N
authors.initials: JN
authors.lastname: Tran
authors.forename: P-J
authors.initials: PJ
authors.lastname: Yang
authors.forename: A G
authors.initials: AG
authors.lastname: Morton
authors.forename: A A
authors.initials: AA
authors.lastname: Todd
authors.forename: J G
authors.initials: JG
authors.lastname: Boulton
authors.forename: A W
authors.initials: AW
authors.lastname: Philbey
mesh_terms: D000818:Animals; D002118:Calcium / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000209:etiology* / Q000473:pathology; D002712:Chlorides / Q000097:blood; D003404:Creatinine / Q000097:blood; D004196:Disease Outbreaks / Q000662:veterinary*; D005260:Female; D006651:Histocytochemistry / Q000662:veterinary; D007674:Kidney Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D031561:Lythrum / Q000378:metabolism* / Q000506:poisoning; D009517:New South Wales; D010758:Phosphorus / Q000097:blood; D010939:Plant Poisoning / Q000662:veterinary*; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood; D014508:Urea / Q000097:blood
chemical_list: D002712:Chlorides; D010758:Phosphorus; D014508:Urea; D012964:Sodium; D003404:Creatinine; D011188:Potassium; D002118:Calcium
keywords: Lythrum hyssopifolia; cattle; nephrosis; plant poisoning