title: Biomolecule-adsorption-dependent piezoelectric output of ZnO nanowire nanogenerator and its application as self-powered active biosensor.
abstract: Self-powered active biosensor has been realized from ZnO nanowire (NW) nanogenerator (NG). The piezoelectric output generated by ZnO NW NG can act not only as a power source for driving the device, but also as a biosensing signal. After immersing in 10(-3) g ml(-1) human immunoglobulin G (IgG), the piezoelectric output voltage of the device under compressive deformation decreases from 0.203±0.0176 V (without IgG) to 0.038±0.0035 V. Such a self-powered biosensor has higher response than transistor-type biosensor (I-V behavior). The response of self-powered biosensor is in a linear relationship with IgG concentration (logarithm, 10(-7)-10(-3) g ml(-1)) and the limit of detection (LOD) on IgG of the device is about 6.9 ng ml(-1). The adsorption of biomolecules on the surface of ZnO NWs can modify the free-carrier density, which vary the screening effect of free-carriers on the piezoelectric output. The present results demonstrate a feasible approach for actively detecting biomolecules by coupling the piezotronic and biosensing characteristics of ZnO NWs.
authors.affiliation: College of Sciences, Northeastern University, Shenyang 110004, China.
authors.forename: Yayu
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: College of Sciences, Northeastern University, Shenyang 110004, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Deng
authors.affiliation: College of Sciences, Northeastern University, Shenyang 110004, China.
authors.forename: Yuxin
authors.initials: Y
authors.lastname: Nie
authors.affiliation: College of Sciences, Northeastern University, Shenyang 110004, China.
authors.forename: Penglei
authors.initials: P
authors.lastname: Wang
authors.affiliation: Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100000, China; Institute of Theoretical Physics, Lanzhou University, Lanzhou 730000, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: College of Sciences, Northeastern University, Shenyang 110004, China. Electronic address: xingrenyier@sina.com.
authors.forename: Lili
authors.initials: L
authors.lastname: Xing
authors.affiliation: College of Sciences, Northeastern University, Shenyang 110004, China; Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100000, China. Electronic address: xuexinyu@mail.neu.edu.cn.
authors.forename: Xinyu
authors.initials: X
authors.lastname: Xue
mesh_terms: D000327:Adsorption; D015374:Biosensing Techniques / Q000295:instrumentation*; D011211:Electric Power Supplies; D004867:Equipment Design; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D057230:Limit of Detection; D036103:Nanotechnology / Q000295:instrumentation; D053770:Nanowires / Q000737:chemistry* / Q000648:ultrastructure; D015034:Zinc Oxide / Q000737:chemistry*
chemical_list: D007074:Immunoglobulin G; D015034:Zinc Oxide
keywords: Biosensor; Nanogenerator; Piezoelectric; Self-powered; ZnO