title: Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites.
abstract: Lipid droplets (LDs) are ubiquitous dynamic organelles that store and supply lipids in all eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and production of essential lipid-derived molecules. Interest in the organelle's cell biology has exponentially increased over the last decade due to the link between LDs and prevalent human diseases and the discovery of new and unexpected functions of LDs. As a result, there has been significant recent progress toward understanding where and how LDs are formed, and the specific lipid pathways that coordinate LD biogenesis.
authors.affiliation: Equip de Compartiments Cellulars i Senyalització, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
authors.forename: Albert
authors.initials: A
authors.lastname: Pol
authors.forename: Steven P
authors.initials: SP
authors.lastname: Gross
authors.forename: Robert G
authors.initials: RG
authors.lastname: Parton
mesh_terms: D000818:Animals; D019556:COS Cells; D002462:Cell Membrane / Q000378:metabolism; D002522:Chlorocebus aethiops; D004734:Energy Metabolism; D005227:Fatty Acids / Q000378:metabolism; D050356:Lipid Metabolism; D053858:Metabolic Networks and Pathways; D051379:Mice; D010743:Phospholipids / Q000096:biosynthesis
chemical_list: D005227:Fatty Acids; D010743:Phospholipids