title: Chondrosarcoma of the chest wall: single-center experience.
abstract: BACKGROUND
  chondrosarcoma is the most common primary tumor of the chest wall. We analyzed cases of chest wall chondrosarcoma to establish the presentation, diagnostic tools, surgical treatment, and outcome.
  
  
  METHODS
  this was a retrospective observational analysis of 45 patients who underwent surgery for chondrosarcoma.
  
  
  RESULTS
  the mean age was 42.3 ± 8.5 years, and 57.8% patients were male. Symptoms were a painful chest wall mass in 91.1% of patients. Chest radiography and computed tomography, and biopsy were the diagnostic tools. The tumor was right-sided in 57.8% of patients. It was located in the lateral (71.1%), anterior (26.7%), or posterior (2.2%) chest wall. The mean tumor diameter was 7.6 ± 3.3 cm. Radical en-bloc excision was performed in all patients. Chest wall reconstruction was carried out using methylmethacrylate and Prolene mesh (42.2%), Prolene mesh alone (37.8%), and direct closure (20%). A muscle flap was used for soft tissue reconstruction in 11.1%. Complications were encountered in 6.7%. There was no operative mortality. Follow-up was complete in 66.7% of patients. The mean follow-up period was 3.7 ± 2.1 years. Local recurrences and late mortality occurred in 4.4%.
  
  
  CONCLUSIONS
  surgery for chondrosarcoma can be performed with acceptable morbidity and mortality. Proper selection of patients and radical en-block excision of the tumor are the keys for successful treatment and better outcomes.
authors.affiliation: Departments of Cardiothoracic Surgery and Anesthesia, Mansoura University Hospitals, Faculty of Medicine, Mansoura University, Egypt redahammad2000@gmail.com.
authors.forename: Reda E
authors.initials: RE
authors.lastname: Al-Refaie
authors.affiliation: Departments of Cardiothoracic Surgery and Anesthesia, Mansoura University Hospitals, Faculty of Medicine, Mansoura University, Egypt.
authors.forename: Sameh
authors.initials: S
authors.lastname: Amer
authors.affiliation: Departments of Cardiothoracic Surgery and Anesthesia, Mansoura University Hospitals, Faculty of Medicine, Mansoura University, Egypt.
authors.forename: Mohammed F
authors.initials: MF
authors.lastname: Ismail
authors.affiliation: Departments of Cardiothoracic Surgery and Anesthesia, Mansoura University Hospitals, Faculty of Medicine, Mansoura University, Egypt.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Al-Shabrawy
authors.affiliation: Departments of Cardiothoracic Surgery and Anesthesia, Mansoura University Hospitals, Faculty of Medicine, Mansoura University, Egypt.
authors.forename: Galal
authors.initials: G
authors.lastname: Al-Gamal
authors.affiliation: Departments of Cardiothoracic Surgery and Anesthesia, Mansoura University Hospitals, Faculty of Medicine, Mansoura University, Egypt.
authors.forename: Ehab
authors.initials: E
authors.lastname: Mokbel
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D001843:Bone Cements / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002813:Chondrosarcoma / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D004534:Egypt; D004867:Equipment Design; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D020366:Methylmethacrylate / Q000627:therapeutic use; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018579:Patient Selection; D011126:Polypropylenes; D011183:Postoperative Complications / Q000209:etiology; D019651:Plastic Surgery Procedures / Q000009:adverse effects / Q000295:instrumentation / Q000401:mortality; D012189:Retrospective Studies; D012307:Risk Factors; D013524:Surgical Flaps; D013526:Surgical Mesh; D062606:Tertiary Care Centers; D013899:Thoracic Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D019616:Thoracic Surgical Procedures / Q000009:adverse effects / Q000295:instrumentation / Q000401:mortality; D035441:Thoracic Wall / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements; D011126:Polypropylenes; D020366:Methylmethacrylate
keywords: Chest wall; Chondrosarcoma; Reconstruction; Recurrence; Ribs