title: Comparison of short-term outcomes after carotid artery stenting according to different stent designs.
abstract: BACKGROUND
  In the developed countries, stroke is the third most common cause of death. There are many data indicating that stents reduce the risk of embolism but there are few publications assessing whether different stent designs can influence the periprocedural complications.
  
  
  OBJECTIVE
  To determine the effects of open- and closed-cell stent designs on 1-month results of carotid artery stenting (CAS).
  
  
  METHODS
  The study group consisted of 290 consecutive patients (216 men and 74 women, mean age 66.6 ±8.7 years). Neuroprotection with a distal protection device was used in all cases. The patients were divided into two groups: the open-cell stent group (n = 144) and the closed-cell stent group (n = 138). Major adverse cardiac and cerebrovascular events (MACCE) described as myocardial infarction, stroke and death within 1 month were recorded and analysed subsequently. Periprocedural hypotension and transient cerebral ischaemia at 1 month after the CAS procedure were also assessed.
  
  
  RESULTS
  We treated 290 carotid stenoses and stents were implanted in all patients. Fifteen patients (5.5%) were treated by staged CAS due to bilateral carotid artery disease. The technical success rate was 97.2%. There was no difference in the MACCE and transient cerebral ischaemia rate at 1 month between the two groups (p = 0.44 and p = 0.94, respectively). The incidence of ischaemic stroke was lower in the closed-cell stent group (2.77% vs. 0%; p = 0.04). The periprocedural rate of hypotension was higher in the closed-cell stent group (2.1% vs. 7.2%; p = 0.04).
  
  
  CONCLUSIONS
  Closed-cell stents are associated with a low rate of ischaemic stroke. We think that closed-cell stents may be preferred in patients at high risk of embolism.
authors.affiliation: Kartal Kosuyolu High Speciality Education and Research Hospital, Istanbul, Turkey.
authors.forename: Muslum
authors.initials: M
authors.lastname: Sahin
authors.affiliation: Kartal Kosuyolu High Speciality Education and Research Hospital, Istanbul, Turkey.
authors.forename: Göksel
authors.initials: G
authors.lastname: Açar
authors.affiliation: Kartal Kosuyolu High Speciality Education and Research Hospital, Istanbul, Turkey.
authors.forename: Birol
authors.initials: B
authors.lastname: Ozkan
authors.affiliation: Kartal Kosuyolu High Speciality Education and Research Hospital, Istanbul, Turkey.
authors.forename: Gökhan
authors.initials: G
authors.lastname: Alıcı
authors.affiliation: Kartal Kosuyolu High Speciality Education and Research Hospital, Istanbul, Turkey.
authors.forename: Mehmet Vefik
authors.initials: MV
authors.lastname: Yazıcıoglu
authors.affiliation: Kartal Kosuyolu High Speciality Education and Research Hospital, Istanbul, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Bulut
authors.affiliation: Kartal Kosuyolu High Speciality Education and Research Hospital, Istanbul, Turkey.
authors.forename: Mehmet Emin
authors.initials: ME
authors.lastname: Kalkan
authors.affiliation: Kartal Kosuyolu High Speciality Education and Research Hospital, Istanbul, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Demir
authors.affiliation: Kartal Kosuyolu High Speciality Education and Research Hospital, Istanbul, Turkey.
authors.forename: Rezzan Deniz
authors.initials: RD
authors.lastname: Acar
authors.affiliation: Kartal Kosuyolu High Speciality Education and Research Hospital, Istanbul, Turkey.
authors.forename: Bilal
authors.initials: B
authors.lastname: Boztosun
keywords: carotid stenting; ischaemic stroke; stent design