title: Prolonged venovenous extracorporeal membrane oxygenation without anticoagulation: a case of Goodpasture syndrome-related pulmonary haemorrhage.
abstract: We present a 16-year-old male with severe acute respiratory and renal failure as a result of Goodpasture syndrome, requiring venovenous extracorporeal membrane oxygenation (VV-ECMO) for pulmonary haemorrhage. The patient received no systemic anticoagulation for 25 of 26 ECMO days (20 days consecutively) and suffered no coagulation-related adverse events. The patient had a subtherapeutic anticoagulation profile according to recommended ECMO guidelines during most of this time. The patient made a full recovery without respiratory compromise, ECMO circuit failure, thrombotic events or the need for ongoing haemodialysis.
authors.affiliation: Intensive Care Unit, St Vincent's Hospital, Sydney, NSW, Australia. daveyherby@gmail.com.
authors.forename: David G
authors.initials: DG
authors.lastname: Herbert
authors.affiliation: Intensive Care Unit, St Vincent's Hospital, Sydney, NSW, Australia.
authors.forename: Hergen
authors.initials: H
authors.lastname: Buscher
authors.affiliation: Intensive Care Unit, St Vincent's Hospital, Sydney, NSW, Australia.
authors.forename: Priya
authors.initials: P
authors.lastname: Nair
mesh_terms: D000293:Adolescent; D019867:Anti-Glomerular Basement Membrane Disease / Q000097:blood / Q000150:complications* / Q000628:therapy; D001777:Blood Coagulation; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D005500:Follow-Up Studies; D006469:Hemoptysis / Q000097:blood / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008297:Male; D013997:Time Factors