title: Myocardial tissue characterization by magnetic resonance imaging: novel applications of T1 and T2 mapping.
abstract: Cardiac magnetic resonance (CMR) imaging is a well-established noninvasive imaging modality in clinical cardiology. Its unsurpassed accuracy in defining cardiac morphology and function and its ability to provide tissue characterization make it well suited for the study of patients with cardiac diseases. Late gadolinium enhancement was a major advancement in the development of tissue characterization techniques, allowing the unique ability of CMR to differentiate ischemic heart disease from nonischemic cardiomyopathies. Using T2-weighted techniques, areas of edema and inflammation can be identified in the myocardium. A new generation of myocardial mapping techniques are emerging, enabling direct quantitative assessment of myocardial tissue properties in absolute terms. This review will summarize recent developments involving T1-mapping and T2-mapping techniques and focus on the clinical applications and future potential of these evolving CMR methodologies.
authors.affiliation: Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford Centre for Clinical Magnetic Resonance Research (OCMR), John Radcliffe Hospital, Oxford, UK.
authors.forename: Vanessa M
authors.initials: VM
authors.lastname: Ferreira
authors.forename: Stefan K
authors.initials: SK
authors.lastname: Piechnik
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Robson
authors.forename: Stefan
authors.initials: S
authors.lastname: Neubauer
authors.forename: Theodoros D
authors.initials: TD
authors.lastname: Karamitsos
mesh_terms: D003287:Contrast Media; D003326:Coronary Circulation; D003937:Diagnosis, Differential; D006331:Heart Diseases / Q000175:diagnosis*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009200:Myocardial Contraction; D009206:Myocardium / Q000473:pathology*; D011237:Predictive Value of Tests; D011379:Prognosis
chemical_list: D003287:Contrast Media