title: The Indian Consensus Document on cardiac biomarker.
abstract: Despite recent advances, the diagnosis and management of heart failure evades the clinicians. The etiology of congestive heart failure (CHF) in the Indian scenario comprises of coronary artery disease, diabetes mellitus and hypertension. With better insights into the pathophysiology of CHF, biomarkers have evolved rapidly and received diagnostic and prognostic value. In CHF biomarkers prove as measures of the extent of pathophysiological derangement; examples include biomarkers of myocyte necrosis, myocardial remodeling, neurohormonal activation, etc. In CHF biomarkers act as indicators for the presence, degree of severity and prognosis of the disease, they may be employed in combination with the present conventional clinical assessments. These make the biomarkers feasible options against the present expensive measurements and may provide clinical benefits.
authors.affiliation: Director, Cardiology, Department of Cardiology at Apollo Hospitals, Chennai, India. Electronic address: drismurthy@gmail.com.
authors.forename: I
authors.initials: I
authors.lastname: Satyamurthy
authors.affiliation: Director, Centre for Cardiac Sciences, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India.
authors.forename: Jamshed J
authors.initials: JJ
authors.lastname: Dalal
authors.affiliation: Chairman, Department of Cardiology and Member, Board of Management at Sir Gangaram Hospital, New Delhi, India.
authors.forename: J P S
authors.initials: JP
authors.lastname: Sawhney
authors.affiliation: Prof., Chief of Cardiology, Jaipur Golden Hospital, New Delhi, India.
authors.forename: J C
authors.initials: JC
authors.lastname: Mohan
authors.affiliation: Clinical Biochemist Breach Candy Hospital, Mumbai, India.
authors.forename: Shubha A
authors.initials: SA
authors.lastname: Chogle
authors.affiliation: Professor and Advisor of Cardiology, SS Medical College and Hospital, Mysore, India.
authors.forename: Nagaraj
authors.initials: N
authors.lastname: Desai
authors.affiliation: Consultant Cardiologist, Director - Cardiology, Deenanath Mangeshkar Hospital, Pune, India.
authors.forename: Shireesh P
authors.initials: SP
authors.lastname: Sathe
authors.affiliation: Director, Coronary Care Unit and Heart Failure Program, VA San Diego, USA.
authors.forename: Alan S
authors.initials: AS
authors.lastname: Maisel
mesh_terms: D015415:Biomarkers / Q000097:blood; D032921:Consensus; D019468:Disease Management; D018450:Disease Progression; D037502:Galectin 3 / Q000097:blood*; D006333:Heart Failure / Q000097:blood* / Q000401:mortality* / Q000628:therapy; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D015996:Survival Rate
chemical_list: D015415:Biomarkers; D037502:Galectin 3; D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain
keywords: Biomarkers; Brain natriuretic peptide; Heart failure; NT-proBNP