title: Optical coherence tomography characteristics of epi-iridic membrane in a child with recurrent hyphema and presumed juvenile xanthogranuloma.
abstract: We report a case of spontaneous hyphema in a 6-month-old girl with no history of trauma and no visible iris mass. Subtle green-blue heterochromia was noted in the right eye. The iris crypts in the right eye appeared flattened by a thin, transparent layer on the iris surface. Anterior segment optical coherence tomography (AS-OCT) disclosed a thin homogenous membrane overlying the entire iris surface in the right eye. Fluorescein angiography revealed diffuse hyperfluorescence without neovascularization. These features were suggestive of diffuse iris juvenile xanthogranuloma. Sub-Tenon's triamcinolone acetate plus topical corticosteroids eyedrops resolved the condition within 1 month.
authors.affiliation: Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.
authors.forename: Fairooz P
authors.initials: FP
authors.lastname: Manjandavida
authors.affiliation: Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.
authors.forename: Sruthi
authors.initials: S
authors.lastname: Arepalli
authors.affiliation: Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.
authors.forename: Bercin
authors.initials: B
authors.lastname: Tarlan
authors.affiliation: Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address: carol.shields@shieldsoncology.com.
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
mesh_terms: D000287:Administration, Topical; D001485:Basement Membrane / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D006988:Hyphema / Q000175:diagnosis* / Q000188:drug therapy; D007223:Infant; D056965:Injections, Intraocular; D015863:Iridocyclitis / Q000175:diagnosis* / Q000188:drug therapy; D007499:Iris Diseases / Q000175:diagnosis* / Q000188:drug therapy; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D012008:Recurrence; D041623:Tomography, Optical Coherence; D014222:Triamcinolone Acetonide / Q000627:therapeutic use; D014972:Xanthogranuloma, Juvenile / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D005938:Glucocorticoids; C009935:prednisolone acetate; D011239:Prednisolone; D014222:Triamcinolone Acetonide