title: Positively charged graphene oxide nanoparticle: precisely label the plasma membrane of live cell and sensitively monitor extracellular pH in situ.
abstract: Polyethylene glycol modified graphene oxide (GO-PEG) nanoparticles were prepared, which were positively charged and fairly stable in buffer solution. The GO-PEG nanoparticles possess a special affinity to the plasma membrane of live cells, and their yellowish-green fluorescence is sensitively responsive to the extracellular physiological solution in situ.
authors.affiliation: Institute of High Energy Physics, Chinese Academy of Sciences, China. gaoxy@ihep.ac.cn.
authors.forename: Huarui
authors.initials: H
authors.lastname: Zhu
authors.forename: Liang
authors.initials: L
authors.lastname: Gao
authors.forename: Xinglu
authors.initials: X
authors.lastname: Jiang
authors.forename: Ru
authors.initials: R
authors.lastname: Liu
authors.forename: Yueteng
authors.initials: Y
authors.lastname: Wei
authors.forename: Yaling
authors.initials: Y
authors.lastname: Wang
authors.forename: Yuliang
authors.initials: Y
authors.lastname: Zhao
authors.forename: Zhifang
authors.initials: Z
authors.lastname: Chai
authors.forename: Xueyun
authors.initials: X
authors.lastname: Gao
mesh_terms: D002462:Cell Membrane / Q000378:metabolism*; D002470:Cell Survival / Q000187:drug effects; D005110:Extracellular Space / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry / Q000494:pharmacology*; D006367:HeLa Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D053758:Nanoparticles / Q000737:chemistry; D010087:Oxides / Q000737:chemistry / Q000494:pharmacology*; D011092:Polyethylene Glycols / Q000737:chemistry / Q000494:pharmacology*; D059016:Tumor Microenvironment
chemical_list: D010087:Oxides; D011092:Polyethylene Glycols; D006108:Graphite