title: [Update on fracture risk in life style-related diseases].
abstract: Accumulating evidence shows that type 2 diabetes and chronic kidney disease (CKD) enhance fracture risk mainly by deteriorating bone quality. Vertebral fracture on X-ray films and hip fracture in past history in subjects of 50 years old or more are hallmarks to start medication for osteoporosis. Patients with diabetes or CKD who have no fracture could undergo drug treatments if their bone mineral density is osteopenic, considering the established link between these disorders and fracture risk.
authors.affiliation: Internal Medicine 1, Shimane University Faculty of Medicine, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Toshitsugu
authors.initials: T
authors.lastname: Sugimoto
mesh_terms: D000367:Age Factors; D050071:Bone Density Conservation Agents / Q000008:administration & dosage*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005598:Fractures, Spontaneous / Q000000981:diagnostic imaging / Q000209:etiology* / Q000517:prevention & control*; D006620:Hip Fractures / Q000000981:diagnostic imaging / Q000209:etiology* / Q000517:prevention & control*; D006801:Humans; D008019:Life Style; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology* / Q000517:prevention & control; D017410:Practice Guidelines as Topic; D011859:Radiography; D051436:Renal Insufficiency, Chronic / Q000150:complications*; D012306:Risk; D016103:Spinal Fractures / Q000000981:diagnostic imaging / Q000209:etiology* / Q000517:prevention & control*
chemical_list: D050071:Bone Density Conservation Agents