title: [Analysis of iodine nutrition and thyroid function of adults in urban areas of Wuwei city Gansu province].
abstract: OBJECTIVE
  To find out the iodine nutrition and thyroid function of adults in urban areas of Wuwei city Gansu province and to provide a basis for scientific iodine supplementation.
  
  
  METHODS
  A cross-sectional survey was performed in 104 adults in Wuwei city form the April 2009 to January 2010. The morning blood samples and one urine samples selected randomly of different people were collected and three free triiodothyronine (FT3), free thyroid hormone (FT4), total triiodothyronine (TT3), total thyroxine (TT4), the thyroid-stimulating hormone (TSH), thyroglobulin antibodies (TGAb), thyroid microsomal antibodies (TMAb) in blood samples and iodine in urine samples were detected.
  
  
  RESULTS
  The medians of urinary iodine were respectively 139.3 microg/L and 212.6 microg/L for male and female, female was significantly higher than male, there were statisticant differences (P < 0.05). TT3, TT4, FT4, FT3 and TSH's mean values were in the normal range, the abnormal ratio of TT3, TT4, FT3, FT4, TSH were respectively 1.9%, 1.0%, 3.8%, 1.9%, 16.3%. The positive rate of TGAb and TMAb in female were all higher than male, there were statisticant differences (P < 0.05). Subclinical hypothyroidism in all thyroid function disorders was most and accounted for 14.4% and female were all higher than male (P < 0.05). The survey were divided into iodine deficiency group, adequate iodine group, over adequate iodine group and iodine excess group for urinary iodine level. The abnormal ratio of TT3, TT4, FT3, FT4, TSH in four groups had no statistically differences, but the positive rate of TGAb and TMAb raised with increased urinary iodine level. Thyroid function disorders occurred in the other three groups except iodine deficiency group, and there were statisticant differences.
  
  
  CONCLUSIONS
  Iodine nutrition level is appropriate for adults in urban areas, but the female was higher than male. Subclinical hypothyroidism in all thyroid function disorders was most, the positive rate of TGAb and TMAb raised with increased urinary iodine level, the risk of female suffered from thyroid disease was higher than male.
authors.affiliation: Gansu Center for Disease Prevention and Control, Lanzhou 730020, China. douygui@sina.com
authors.forename: Yugui
authors.initials: Y
authors.lastname: Dou
authors.affiliation: Gansu Center for Disease Prevention and Control, Lanzhou 730020, China.
authors.forename: Yanling
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Gansu Center for Disease Prevention and Control, Lanzhou 730020, China.
authors.forename: Tingcai
authors.initials: T
authors.lastname: Wang
authors.affiliation: Gansu Center for Disease Prevention and Control, Lanzhou 730020, China.
authors.forename: Liping
authors.initials: L
authors.lastname: Liang
authors.affiliation: Gansu Center for Disease Prevention and Control, Lanzhou 730020, China.
authors.forename: Xudong
authors.initials: X
authors.lastname: Ren
authors.affiliation: Gansu Center for Disease Prevention and Control, Lanzhou 730020, China.
authors.forename: Hongbo
authors.initials: H
authors.lastname: Li
authors.affiliation: Gansu Center for Disease Prevention and Control, Lanzhou 730020, China.
authors.forename: Xiaonan
authors.initials: X
authors.lastname: Zhu
mesh_terms: D000293:Adolescent; D000328:Adult; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000453:epidemiology*; D007455:Iodine / Q000008:administration & dosage* / Q000652:urine; D008297:Male; D012737:Sex Factors; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000502:physiology*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood; D014505:Urban Population; D055815:Young Adult
chemical_list: D014284:Triiodothyronine; D013972:Thyrotropin; D007455:Iodine; D013974:Thyroxine