title: BicOverlapper 2.0: visual analysis for gene expression.
abstract: BACKGROUND
  Systems biology demands the use of several point of views to get a more comprehensive understanding of biological problems. This usually leads to take into account different data regarding the problem at hand, but it also has to do with using different perspectives of the same data. This multifaceted aspect of systems biology often requires the use of several tools, and it is often hard to get a seamless integration of all of them, which would help the analyst to have an interactive discourse with the data.
  
  
  RESULTS
  Focusing on expression profiling, BicOverlapper 2.0 visualizes the most relevant aspects of the analysis, including expression data, profiling analysis results and functional annotation. It also integrates several state-of-the-art numerical methods, such as differential expression analysis, gene set enrichment or biclustering.
  
  
  METHODS
  BicOverlapper 2.0 is available at: http://vis.usal.es/bicoverlapper2
authors.affiliation: Department of Computer Science, University of Salamanca, 37008 Salamanca, Spain and Instituto de Biología Funcional y Genómica, CSIC/USAL, 37007 Salamanca, Spain.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Santamaría
authors.affiliation: Department of Computer Science, University of Salamanca, 37008 Salamanca, Spain and Instituto de Biología Funcional y Genómica, CSIC/USAL, 37007 Salamanca, Spain.
authors.forename: Roberto
authors.initials: R
authors.lastname: Therón
authors.affiliation: Department of Computer Science, University of Salamanca, 37008 Salamanca, Spain and Instituto de Biología Funcional y Genómica, CSIC/USAL, 37007 Salamanca, SpainDepartment of Computer Science, University of Salamanca, 37008 Salamanca, Spain and Instituto de Biología Funcional y Genómica, CSIC/USAL, 37007 Salamanca, Spain.
authors.forename: Luis
authors.initials: L
authors.lastname: Quintales
mesh_terms: D003196:Computer Graphics; D020869:Gene Expression Profiling / Q000379:methods*; D012984:Software; D049490:Systems Biology / Q000379:methods