title: Development of Clostridium septicum gas gangrene as an adverse effect of clindamycin-induced Clostridium difficile infection in a pediatric patient.
abstract: Clostridium myonecrosis or gas gangrene is a life-threatening infection characterized by either traumatic or atraumatic etiology. It has been widely described in patients with traumatic open wounds and in immunocompromised patients, including malignancy. A third source can result from natural flora in the gastrointestinal tract after bowel ischemia. This is a rare occurrence and is even less commonly described in the pediatric population. We present a pediatric patient who developed Clostridium septicum myonecrosis as an iatrogenic complication from clindamycin-induced Clostridium difficile ischemic colitis.
authors.affiliation: Department of Orthopaedics and Rehabilitation, College of Medicine, The Pennsylvania State University, Hershey, PA.
authors.forename: Casey J
authors.initials: CJ
authors.lastname: Kiser
authors.forename: Kenneth L
authors.initials: KL
authors.lastname: Urish
authors.forename: Henry A
authors.initials: HA
authors.lastname: Boateng
mesh_terms: D002648:Child; D002981:Clindamycin / Q000009:adverse effects*; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000209:etiology*; D052557:Clostridium septicum; D017091:Colitis, Ischemic / Q000382:microbiology; D005260:Female; D005738:Gas Gangrene / Q000209:etiology*; D006801:Humans; D007049:Iatrogenic Disease; D012772:Shock, Septic / Q000209:etiology
chemical_list: D002981:Clindamycin