title: Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia.
authors.affiliation: Hematology Research Unit Helsinki, Department of Medicine, University of Helsinki and Helsinki University Central Hospital Cancer Center, Helsinki, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Kontro
authors.affiliation: 1] Hematology Research Unit Helsinki, Department of Medicine, University of Helsinki and Helsinki University Central Hospital Cancer Center, Helsinki, Finland [2] Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
authors.forename: H
authors.initials: H
authors.lastname: Kuusanmäki
authors.affiliation: Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
authors.forename: S
authors.initials: S
authors.lastname: Eldfors
authors.affiliation: Department of Hematology, Oncology, and Tumor Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Burmeister
authors.affiliation: Hematology Research Unit Helsinki, Department of Medicine, University of Helsinki and Helsinki University Central Hospital Cancer Center, Helsinki, Finland.
authors.forename: E I
authors.initials: EI
authors.lastname: Andersson
authors.affiliation: 1] Department of Clinical Science, Hematology Section, University of Bergen, Bergen, Norway [2] Department of Internal Medicine, Hematology Section, Haukeland University Hospital, Bergen, Norway.
authors.forename: O
authors.initials: O
authors.lastname: Bruserud
authors.affiliation: Department of Oncology, Hematology and Stem Cell Transplantation, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.
authors.forename: T H
authors.initials: TH
authors.lastname: Brümmendorf
authors.affiliation: Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
authors.forename: H
authors.initials: H
authors.lastname: Edgren
authors.affiliation: 1] Department of Clinical Science, Hematology Section, University of Bergen, Bergen, Norway [2] Department of Internal Medicine, Hematology Section, Haukeland University Hospital, Bergen, Norway.
authors.forename: B T
authors.initials: BT
authors.lastname: Gjertsen
authors.affiliation: Department of Clinical Hematology, Turku University Central Hospital, University of Turku, Turku, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Itälä-Remes
authors.affiliation: Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
authors.forename: S
authors.initials: S
authors.lastname: Lagström
authors.affiliation: Tampere Center for Child Health Research, University of Tampere School of Medicine and Tampere University Hospital, Tampere, Finland.
authors.forename: O
authors.initials: O
authors.lastname: Lohi
authors.affiliation: Department of Clinical Chemistry and TYKSLAB, Turku University Central Hospital, University of Turku, Turku, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Lundán
authors.affiliation: Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
authors.forename: J M L
authors.initials: JM
authors.lastname: Martí
authors.affiliation: Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
authors.forename: M M
authors.initials: MM
authors.lastname: Majumder
authors.affiliation: Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Parsons
authors.affiliation: Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Pemovska
authors.affiliation: Hematology Research Unit Helsinki, Department of Medicine, University of Helsinki and Helsinki University Central Hospital Cancer Center, Helsinki, Finland.
authors.forename: H
authors.initials: H
authors.lastname: Rajala
authors.affiliation: Division of Hematology-Oncology and Stem Cell Transplantation, Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Vettenranta
authors.affiliation: Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
authors.forename: O
authors.initials: O
authors.lastname: Kallioniemi
authors.affiliation: Hematology Research Unit Helsinki, Department of Medicine, University of Helsinki and Helsinki University Central Hospital Cancer Center, Helsinki, Finland.
authors.forename: S
authors.initials: S
authors.lastname: Mustjoki
authors.affiliation: Hematology Research Unit Helsinki, Department of Medicine, University of Helsinki and Helsinki University Central Hospital Cancer Center, Helsinki, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Porkka
authors.affiliation: 1] Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland [2] Institute of Biomedicine, University of Helsinki, Helsinki, Finland.
authors.forename: C A
authors.initials: CA
authors.lastname: Heckman
mesh_terms: D000293:Adolescent; D006801:Humans; D009154:Mutation; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000235:genetics*; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000037:antagonists & inhibitors; D050799:STAT5 Transcription Factor / Q000235:genetics*; D051020:bcl-X Protein / Q000235:genetics
chemical_list: C494811:BCL2L1 protein, human; D019253:Proto-Oncogene Proteins c-bcl-2; D050799:STAT5 Transcription Factor; C494095:STAT5B protein, human; D051020:bcl-X Protein