title: Chronic progressive lymphoedema in draught horses.
abstract: The objective of this review was to summarise and evaluate the current state of knowledge about chronic progressive lymphoedema in draught horses. Clinical signs of this multifactorial disorder are mainly restricted to the lower limbs, comprising progressively deteriorating skin, swelling and deformation. Although typical lesions were first reported at the beginning of the 20th century, chronic progressive lymphoedema was recognised as a specific syndrome only in 2003, and since then research has driven forward. Despite the high prevalence in some breeds and the serious economic impact, the pathogenesis is not fully understood, and the available treatment options remain symptomatic and noncurative. There is a need to improve diagnostic techniques and to develop selection tools.
authors.affiliation: Livestock Genetics, Department of Biosystems, KU Leuven, Heverlee (Leuven), Belgium.
authors.forename: K
authors.initials: K
authors.lastname: de Keyser
authors.forename: S
authors.initials: S
authors.lastname: Janssens
authors.forename: N
authors.initials: N
authors.lastname: Buys
mesh_terms: D000818:Animals; D020022:Genetic Predisposition to Disease; D006734:Horse Diseases / Q000235:genetics / Q000473:pathology*; D006736:Horses; D008209:Lymphedema / Q000473:pathology / Q000662:veterinary*
keywords: chronic progressive lymphoedema; clinical signs; draught horse; horse; molecular genetics; quantitative genetics