title: Impact of delivery models on understanding genomic risk for type 2 diabetes.
abstract: BACKGROUND
  Genetic information, typically communicated in-person by genetic counselors, can be challenging to comprehend; delivery of this information online--as is becoming more common--has the potential of increasing these challenges.
  
  
  METHODS
  To address the impact of the mode of delivery of genomic risk information, 300 individuals were recruited from the general public and randomized to receive genomic risk information for type 2 diabetes mellitus in-person from a board-certified genetic counselor or online through the testing company's website.
  
  
  RESULTS
  Participants were asked to indicate their genomic risk and overall lifetime risk as reported on their test report as well as to interpret their genomic risk (increased, decreased, or same as population). For each question, 59% of participants correctly indicated their risk. Participants who received their results in-person were more likely than those who reviewed their results on-line to correctly interpret their genomic risk (72 vs. 47%, p = 0.0002) and report their actual genomic risk (69 vs. 49%, p = 0.002).
  
  
  CONCLUSIONS
  The delivery of personal genomic risk through a trained health professional resulted in significantly higher comprehension. Therefore, if the online delivery of genomic test results is to become more widespread, further evaluation of this method of communication may be needed to ensure the effective presentation of results to promote comprehension.
authors.affiliation: Duke Institute for Genome Sciences and Policy, Duke University, Durham, N.C., USA.
authors.forename: S B
authors.initials: SB
authors.lastname: Haga
authors.forename: W T
authors.initials: WT
authors.lastname: Barry
authors.forename: R
authors.initials: R
authors.lastname: Mills
authors.forename: L
authors.initials: L
authors.lastname: Svetkey
authors.forename: S
authors.initials: S
authors.lastname: Suchindran
authors.forename: H F
authors.initials: HF
authors.lastname: Willard
authors.forename: G S
authors.initials: GS
authors.lastname: Ginsburg
mesh_terms: D000293:Adolescent; D000328:Adult; D003142:Communication; D032882:Comprehension; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics* / Q000523:psychology; D005260:Female; D005817:Genetic Counseling / Q000379:methods* / Q000523:psychology; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D015894:Genome, Human / Q000235:genetics*; D023281:Genomics; D006801:Humans; D020407:Internet; D008297:Male; D010353:Patient Education as Topic / Q000379:methods*; D055815:Young Adult