title: Refractory atrial fibrillation effectively treated with ranolazine.
abstract: Atrial fibrillation is the most common sustained cardiac arrhythmia which is often troublesome to manage. Currently, rhythm and rate control medications are the mainstays of therapy. In 2 amiodarone-refractory highly symptomatic patients, an innovative approach using ranolazine, which selectively acts on Na+ channels and delays atrial depolarization, was tried successfully.
authors.affiliation: Medical Student, Dr. D.Y. Patil Medical College, Navi Mumbai, India.
authors.forename: Aditi
authors.initials: A
authors.lastname: Vaishnav
authors.affiliation: Medical Student, Dr. D.Y. Patil Medical College, Navi Mumbai, India.
authors.forename: Avani
authors.initials: A
authors.lastname: Vaishnav
authors.affiliation: Arrhythmia Associates, Mumbai, India. Electronic address: yashlokhandwala@hotmail.com.
authors.forename: Yash
authors.initials: Y
authors.lastname: Lokhandwala
mesh_terms: D000083:Acetanilides / Q000008:administration & dosage*; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology*; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications* / Q000175:diagnosis; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004562:Electrocardiography / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000008:administration & dosage*; D000069458:Ranolazine; D012008:Recurrence; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000083:Acetanilides; D010879:Piperazines; D000069458:Ranolazine
keywords: Anti-arrhythmic drugs; Arrhythmias; Cardioversion