title: Reducing antimicrobial therapy for asymptomatic bacteriuria among noncatheterized inpatients: a proof-of-concept study.
abstract: This proof-of-concept study demonstrates that no longer routinely reporting urine culture results from noncatheterized medical and surgical inpatients can greatly reduce unnecessary antimicrobial therapy for asymptomatic bacteriuria without significant additional laboratory workload. Larger studies are needed to confirm the generalizability, safety, and sustainability of this model of care.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, University of Toronto.
authors.forename: Jerome A
authors.initials: JA
authors.lastname: Leis
authors.forename: Gabriel W
authors.initials: GW
authors.lastname: Rebick
authors.forename: Nick
authors.initials: N
authors.lastname: Daneman
authors.forename: Wayne L
authors.initials: WL
authors.lastname: Gold
authors.forename: Susan M
authors.initials: SM
authors.lastname: Poutanen
authors.forename: Pauline
authors.initials: P
authors.lastname: Lo
authors.forename: Michael
authors.initials: M
authors.lastname: Larocque
authors.forename: Kaveh G
authors.initials: KG
authors.lastname: Shojania
authors.forename: Allison
authors.initials: A
authors.lastname: McGeer
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D058345:Asymptomatic Infections; D001437:Bacteriuria / Q000175:diagnosis / Q000188:drug therapy*; D004358:Drug Therapy / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007297:Inpatients; D008297:Male; D019564:Unnecessary Procedures; D014552:Urinary Tract Infections / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D000890:Anti-Infective Agents
keywords: antimicrobial stewardship; asymptomatic bacteriuria; urine culture