title: Top-down regulation of left temporal cortex by hypnotic amusia for rhythm: a pilot study on mismatch negativity.
abstract: To evaluate the effect of hypnotically induced amusia for rhythm (a condition in which individuals are unable to recognize melodies or rhythms) on mismatch negativity (MMN), 5 highly (HH) and 5 poorly (LH) hypnotizable nonmusician volunteers underwent MMN recording before and during a hypnotic suggestion for amusia. MMN amplitude was recorded using a 19-channel montage and then processed using the low-resolution electromagnetic tomography (LORETA) to localize its sources. MMN amplitude was significantly decreased during hypnotic amusia (p < .04) only in HH, where the LORETA maps of MMN showed a decreased source amplitude in the left temporal lobe, suggesting a hypnotic top-down regulation of activity of these areas and that these changes can be assessed by neurophysiological investigations.
authors.affiliation: a University of Padua and Italian Center for Clinical and Experimental Hypnosis , Turin , Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Facco
authors.forename: Mario
authors.initials: M
authors.lastname: Ermani
authors.forename: Patrizia
authors.initials: P
authors.lastname: Rampazzo
authors.forename: Valérie
authors.initials: V
authors.lastname: Tikhonoff
authors.forename: Marina
authors.initials: M
authors.lastname: Saladini
authors.forename: Gastone
authors.initials: G
authors.lastname: Zanette
authors.forename: Edoardo
authors.initials: E
authors.lastname: Casiglia
authors.forename: David
authors.initials: D
authors.lastname: Spiegel
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D001288:Attention / Q000502:physiology; D001308:Auditory Perceptual Disorders / Q000503:physiopathology*; D001931:Brain Mapping; D004292:Dominance, Cerebral / Q000502:physiology*; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D006990:Hypnosis; D008297:Male; D010865:Pilot Projects; D010898:Pitch Perception / Q000502:physiology; D013404:Suggestion; D013702:Temporal Lobe / Q000503:physiopathology*