title: Investigation of the effects of preoperative hydration on the postoperative nausea and vomiting.
abstract: BACKGROUND
  Postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy operations still continue to be a serious problem. Intravenous fluid administration has been shown to reduce PONV. Some patients have higher risk for PONV described by APFEL score. In this study, our aim was to determine the effects of preoperative intravenous hydration on postoperative nausea and vomiting in high Apfel scored patients undergoing laparoscopic cholecystectomy surgery.
  
  
  METHODS
  This study is performed with 50 female patients who had APFEL score 3-4 after ethics committee approval and informed consent was taken from patients. The patients were divided into 2 groups: group 1 (P1): propofol + preoperative hydration and group 2 (P2): propofol + no preoperative hydration.
  
  
  RESULTS
  When the total nausea VAS scores of groups P1 and P2 to which hydration was given or not given were compared, a statistically significant difference was detected at 8th and 12th hours (P = 0.001 and P = 0.041). It was observed that in group P1, which was given hydration, the nausea VAS score was lower. When the total number of patients who had nausea and vomiting in P1 and P2, more patients suffered nausea in P2 group.
  
  
  CONCLUSIONS
  Preoperative hydration may be effective in high Apfel scored patients to prevent postoperative nausea.
authors.affiliation: Duatepe Polatlı State Hospital, Ankara, Turkey.
authors.forename: M Selçuk
authors.initials: MS
authors.lastname: Yavuz
authors.affiliation: Türkiye Yüksek İhtisas Education and Research Hospital, Anesthesiology and Reanimation Clinic, Kızılay Street No. 4, Samanpazarı Altındağ, Ankara, Turkey.
authors.forename: Dilek
authors.initials: D
authors.lastname: Kazancı
authors.affiliation: Türkiye Yüksek İhtisas Education and Research Hospital, Anesthesiology and Reanimation Clinic, Kızılay Street No. 4, Samanpazarı Altındağ, Ankara, Turkey.
authors.forename: Sema
authors.initials: S
authors.lastname: Turan
authors.affiliation: Türkiye Yüksek İhtisas Education and Research Hospital, Anesthesiology and Reanimation Clinic, Kızılay Street No. 4, Samanpazarı Altındağ, Ankara, Turkey.
authors.forename: Bahar
authors.initials: B
authors.lastname: Aydınlı
authors.affiliation: Türkiye Yüksek İhtisas Education and Research Hospital, Anesthesiology and Reanimation Clinic, Kızılay Street No. 4, Samanpazarı Altındağ, Ankara, Turkey.
authors.forename: Gökçe
authors.initials: G
authors.lastname: Selçuk
authors.affiliation: Türkiye Yüksek İhtisas Education and Research Hospital, Anesthesiology and Reanimation Clinic, Kızılay Street No. 4, Samanpazarı Altındağ, Ankara, Turkey.
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Özgök
authors.affiliation: Gülhane Military Medicine Faculty, Anesthesiology and Reanimation Department, Ankara, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Coşar
mesh_terms: D003710:Demography; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D008787:Metoclopramide / Q000627:therapeutic use; D010147:Pain Measurement; D020250:Postoperative Nausea and Vomiting / Q000188:drug therapy / Q000628:therapy*; D011300:Preoperative Care
chemical_list: D008787:Metoclopramide