title: Surgical treatment of osteopetrosis-related femoral fractures: two case reports and literature review.
abstract: Osteopetrosis is a rare hereditary disease which is characterized by increased bone density. Bone resorption is insufficient or fails due to the osteoclast defect in osteopetrosis. Half of the patients are asymptomatic and diagnosed incidentally or based on the presence of fracture. Adult onset osteopetrosis usually presents with hip and proximal femoral fractures. Internal fixation can be performed; however, technical challenges may be experienced due to increased bone density. As in other fractures, nonunion or varus malunion of these fractures may occur. Although rare, osteopetrosis may complicate treatment of fractures in such patients. In this study, we aimed to present two new cases of ADO type II with an osteopetrotic femoral fracture along with the clinical and radiological findings in the light of a comprehensive literature review. Orthopaedics surgeons should be aware of intraoperative technical difficulties and possible postoperative complications during the follow-up period. Investigation would be beneficial for the diagnosis of osteopetrosis such the patient with fractures who has minor trauma history and increased bone density in radiography.
authors.affiliation: Departments of Orthopaedics and Traumatology, Afyonkarahisar State Hospital, Orhangazi Mh. Nedim Helvacıoglu Cd. No. 73 Uydukent, 03100 Afyonkarahisar, Turkey.
authors.forename: Ahmet
authors.identifier: 0000-0001-5797-1287
authors.initials: A
authors.lastname: Aslan
authors.affiliation: Departments of Orthopaedics and Traumatology, Medical Faculty, Süleyman Demirel University, Isparta, Turkey.
authors.forename: Yakup Barbaros
authors.initials: YB
authors.lastname: Baykal
authors.affiliation: Department of Emergency and First Aid, Bağcılar Education and Research Hospital, Istanbul, Turkey.
authors.forename: Emin
authors.initials: E
authors.lastname: Uysal
authors.affiliation: Departments of Orthopaedics and Traumatology, Medical Faculty, Süleyman Demirel University, Isparta, Turkey.
authors.forename: Tolga
authors.identifier: 0000-0002-1429-9109
authors.initials: T
authors.lastname: Atay
authors.affiliation: Departments of Orthopaedics and Traumatology, Medical Faculty, Süleyman Demirel University, Isparta, Turkey.
authors.forename: Vecihi
authors.initials: V
authors.lastname: Kirdemir
authors.affiliation: TBMM, Ankara, Turkey.
authors.forename: Metin Lütfi
authors.initials: ML
authors.lastname: Baydar
authors.affiliation: Departments of Orthopaedics and Traumatology, Ankara Education and Research Hospital, Ankara, Turkey.
authors.forename: Nevres Hürriyet
authors.initials: NH
authors.lastname: Aydoğan