title: Chlamydia trachomatis IgM seropositivity during pregnancy and assessment of its risk factors.
abstract: The study was undertaken to determine socio-demographic and reproductive risk factors associated with Chlamydia trachomaties IgM seropositivity during pregnancy. This cross sectional comparative study was carried out in the obstetrics outdoor of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh in collaboration with the department of Virology between the periods from July 2007 to December 2008. Pregnant women at their first visit to the hospital were approached consecutively and asked to complete a questionnaire and 2cc blood was collected from each subject for Chlamydia trachomatis IgM antibody testing using ELISA method. The study population was divided into two groups according to the presence and absence of serum Chlamydia trachomatis IgM antibody. Finally socio-demographic and reproductive risk factors were compared between the groups. Among 172 women the sero-prevalence of Chlamydia IgM was 41%. The multiple logistic regression model (step wise) finally extracted for characteristics correlated with seropositivity. Ten years or less (≤SSC) education (OR 2.6 95% CI 1.1to 5.9), history of adverse pregnancy outcome (OR 2.8 95% CI 1.2 to 6.5) and multiple sex partner of husband (OR 4.1 95% CI 1.2 to 14.8) were associated with chlamydia infection. The use of condom (OR 0.28 95% CI 0.12 to 0.63) was associated with decreased risk of infection. Chlamydia trachomatis infection during pregnancy is associated with risk factors on the basis of which selective screening can be done.
authors.affiliation: Dr Mahfuza Rahman, MS (Thesis) Student (Obs & Gynae), Bangabandhu Sheikh Mujib Medical Universtiy (BSMMU), Shahbagh, Dhaka, Bangladesh.
authors.forename: M
authors.initials: M
authors.lastname: Rahman
authors.forename: S B
authors.initials: SB
authors.lastname: Chowdhury
authors.forename: N
authors.initials: N
authors.lastname: Akhtar
authors.forename: M
authors.initials: M
authors.lastname: Jahan
authors.forename: M K
authors.initials: MK
authors.lastname: Jahan
authors.forename: S
authors.initials: S
authors.lastname: Jebunnahar
mesh_terms: D000293:Adolescent; D000328:Adult; D001459:Bangladesh / Q000453:epidemiology; D002690:Chlamydia Infections / Q000453:epidemiology* / Q000276:immunology*; D002692:Chlamydia trachomatis / Q000276:immunology*; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000276:immunology*; D012307:Risk Factors; D016036:Seroepidemiologic Studies
chemical_list: D007075:Immunoglobulin M