title: Temporal correlation of spontaneous hemodynamic activity in language areas measured with functional near-infrared spectroscopy.
abstract: Functional near-infrared spectroscopy (fNIRS) was used to investigate resting state connectivity of language areas including bilateral inferior frontal gyrus (IFG) and superior temporal gyrus (STG). Thirty-two subjects participated in the experiment, including twenty adults and twelve children. Spontaneous hemodynamic fluctuations were recorded, and then intra- and inter-hemispheric temporal correlations of these signals were computed. The correlations of all hemoglobin components were observed significantly higher for adults than children. Moreover, the differences for the STG were more significant than for the IFG. In the adult group, differences in the correlations between males and females were not significant. Our results suggest by measuring resting state intra- and inter-hemispheric correlations, fNIRS is able to provide qualitative and quantitative evaluation on the functioning of the cortical network.
authors.affiliation: South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, 510006, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.affiliation: South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, 510006, China.
authors.forename: Lina
authors.initials: L
authors.lastname: Qiu
keywords: (170.2655) Functional monitoring and imaging; (170.3880) Medical and biological imaging; (170.5380) Physiology