title: Professor David Poswillo CBE (1927-2003): Skilled oral and maxillofacial surgeon, influential scientist, teacher and adviser.
abstract: David Poswillo trained at Otago University Dental School, Dunedin, New Zealand (BDS) and the Royal College of Surgeons of England (FDSRCS). His great interest became the genesis and repair of cleft lip and palate and, in addition to clinical work, he undertook an experimental study of the embryology of cleft palate in pregnant rats exposed to three teratogenic agents. The microscopic work was carried out in his garden shed in Christchurch. His groundbreaking work on amniotic puncture at a critical period came to international notice and he was given the first Chair in Teratology of the Royal College of Surgeons. In experimental studies he showed that thalidomide induced focal haemorrhage in the developing embryo. Poswillo was also Consultant Oral Surgeon at Queen Victoria Hospital, East Grinstead and his skills as surgeon and teacher attracted numerous trainee surgeons. He was Professor of Oral Surgery in Adelaide and then in London. Poswillo was Chairman of two advisory committees whose lucid reports on anaesthesia, sedation and resuscitation in dentistry (Poswillo Report) and on tobacco and health were far-reaching and influential. David Poswillo had immense energy and enthusiasm and is remembered by many for his personal interest and stimulating guidance.
authors.affiliation: Retired Physiologist, King's College, London, UK.
authors.forename: Barbara J
authors.initials: BJ
authors.lastname: Hawgood
mesh_terms: D000818:Animals; D002972:Cleft Palate / Q000139:chemically induced / Q000266:history*; D004739:England; D005179:Faculty, Dental / Q000266:history; D005260:Female; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D009520:New Zealand; D011247:Pregnancy; D013515:Surgery, Oral / Q000266:history*; D018600:Teratology / Q000266:history*; D013792:Thalidomide / Q000009:adverse effects / Q000266:history
chemical_list: D013792:Thalidomide
keywords: Cleft palate; Pierre Robin syndrome; Poswillo Report; hypervitaminosis A; otomandibular malformation; thalidomide