title: Sequential hydrozirconation/cyclization of dienes, a new route toward trans 2-substituted vinylcyclopentanes.
abstract: The diastereoselective synthesis of trans-2-substituted vinylcyclopentanes is described. The method is based on the intramolecular coupling of 7-methoxy-1,5-dienes involving a sequential activation of the C═C double bonds via hydrozirconation and TMSOTf-promoted allylation.
authors.affiliation: Institut de Chimie Moléculaire de Reims, CNRS (UMR 7312) and Université de Reims , 51687 Reims Cedex 2, France.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Clergue
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Vasse
mesh_terms: D000466:Alkadienes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism; D014753:Vinyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000466:Alkadienes; D003517:Cyclopentanes; D014753:Vinyl Compounds