title: Risk factors of CVD mortality among the elderly in Beijing, 1992 - 2009: an 18-year cohort study.
abstract: Few researchers have examined the effects of multiple risk factors of cardiovascular disease (CVD) mortality simultaneously. This study was to determine the associations of combined lifestyle and other factors with CVD mortality among the elderly (n = 3,257), in Beijing, China, through data mining of the Beijing Longitudinal Study of Aging (BLSA). BLSA is a representative cohort study from 1992 to 2009, hosted by Xuan Wu Hospital. Competing risk survival analysis was conducted to explore the association between risk factors and CVD mortality. The factors focused mainly on lifestyle, physical condition, and the model was adjusted for age and gender. There were 273 of the 1,068 recorded deaths caused by CVD among the 2010 participants. Living in a suburban area (HR = 0.614, 95% CI: 0.410-0.921) was associated with lower CVD mortality. Increasing age (66-75: HR = 1.511, 95% CI: 1.111-2.055; ≥ 76: HR = 1.847, 95% CI: 1.256-2.717), high blood pressure (HR = 1.407, 95% CI: 1.031-1.920), frequent consumption of meat (HR = 1.559, 95% CI: 1.079-2.254) and physical inactivity (p = 0.046) were associated with higher CVD mortality. The study provides an instructional foundation for the control and prevention of CVD in Beijing, China.
authors.affiliation: School of Public Health, Capital Medical University, 10 Xitoutiao, Youanmen, Beijing 100069, China. zhoutaosmile@126.com.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhou
authors.affiliation: School of Public Health, Capital Medical University, 10 Xitoutiao, Youanmen, Beijing 100069, China. lixia_new@163.com.
authors.forename: Xia
authors.initials: X
authors.lastname: Li
authors.affiliation: Xuan Wu Hospital, Capital Medical University, 45 Changchun Street, Beijing 100069, China. tangzhe@medmail.com.cn.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Tang
authors.affiliation: Division of Epidemiology and Biostatistics, Department of Environmental Health, University of Cincinnati, Ohio, OH 45267, USA. xiecn@ucmail.uc.edu.
authors.forename: Changchun
authors.initials: C
authors.lastname: Xie
authors.affiliation: School of Public Health, Capital Medical University, 10 Xitoutiao, Youanmen, Beijing 100069, China. taolixin.2008@163.com.
authors.forename: Lixin
authors.initials: L
authors.lastname: Tao
authors.affiliation: School of Public Health, Capital Medical University, 10 Xitoutiao, Youanmen, Beijing 100069, China. panlei_helen@163.com.
authors.forename: Lei
authors.initials: L
authors.lastname: Pan
authors.affiliation: Institute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control, No. 16 Hepingli Middle Street, Dongcheng District, Beijing 100013, China. howardhuo@139.com.
authors.forename: Da
authors.initials: D
authors.lastname: Huo
authors.affiliation: Xuan Wu Hospital, Capital Medical University, 45 Changchun Street, Beijing 100069, China. sf69@163.com.
authors.forename: Fei
authors.initials: F
authors.lastname: Sun
authors.affiliation: School of Public Health, Capital Medical University, 10 Xitoutiao, Youanmen, Beijing 100069, China. lyx100@ccmu.edu.cn.
authors.forename: Yanxia
authors.initials: Y
authors.lastname: Luo
authors.affiliation: School of Medical Science, Edith Cowan University, 2 Bradford Street, Mount Lawley, Massachusetts, WA 6050, Australia. wei6014@yahoo.com.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.affiliation: Beijing Municipal Science and Technology Commission, Sijiqing Street, Beijing 100195, China. hnlg0771@hotmail.com.
authors.forename: Aoshuang
authors.initials: A
authors.lastname: Yan
authors.affiliation: School of Public Health, Capital Medical University, 10 Xitoutiao, Youanmen, Beijing 100069, China. statguo@ccmu.edu.cn.
authors.forename: Xiuhua
authors.initials: X
authors.lastname: Guo
mesh_terms: D000368:Aged; D002318:Cardiovascular Diseases / Q000401:mortality*; D002681:China / Q000453:epidemiology; D002947:Cities / Q000706:statistics & numerical data; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors