title: Monoterpene glycosides, phenylpropanoids, and acacetin glycosides from Dracocephalum foetidum.
abstract: Chemical investigation of the acetone extract from the aerial parts of the Mongolian medicinal plant Dracocephalum foetidum resulted in the isolation of three limonene glycosides, a caffeic acid trimer, four rosmarinic acid glucosides, and five acacetin acyl glycosides, together with 13 known natural products. The chemical structures of all of the compounds were determined by spectroscopic analyses. Among these compounds three showed hyaluronidase inhibitory activity. In addition, one other compound showed stronger 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity than the positive control Trolox, whereas three other compounds demonstrated a similar activity to that of Trolox.
authors.affiliation: Department of Pharmacognosy, Tohoku Pharmaceutical University, 4-1 Komatsushima 4-chome Aoba-ku, Sendai 981-8558, Japan.
authors.forename: Erdenechimeg
authors.initials: E
authors.lastname: Selenge
authors.affiliation: Department of Pharmacognosy, Tohoku Pharmaceutical University, 4-1 Komatsushima 4-chome Aoba-ku, Sendai 981-8558, Japan. Electronic address: murata-t@tohoku-pharm.ac.jp.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Murata
authors.affiliation: Department of Pharmacognosy, Tohoku Pharmaceutical University, 4-1 Komatsushima 4-chome Aoba-ku, Sendai 981-8558, Japan.
authors.forename: Shiho
authors.initials: S
authors.lastname: Tanaka
authors.affiliation: Department of Pharmacognosy, Tohoku Pharmaceutical University, 4-1 Komatsushima 4-chome Aoba-ku, Sendai 981-8558, Japan.
authors.forename: Kenroh
authors.initials: K
authors.lastname: Sasaki
authors.affiliation: School of Biology and Biotechnology, National University of Mongolia, PO Box 617, Ulaanbaatar 46A, Mongolia.
authors.forename: Javzan
authors.initials: J
authors.lastname: Batkhuu
authors.affiliation: Department of Pharmacognosy, Tohoku Pharmaceutical University, 4-1 Komatsushima 4-chome Aoba-ku, Sendai 981-8558, Japan.
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Yoshizaki
mesh_terms: D000975:Antioxidants / Q000302:isolation & purification*; D001713:Biphenyl Compounds / Q000737:chemistry; D047309:Flavones / Q000302:isolation & purification*; D006027:Glycosides / Q000302:isolation & purification*; D006821:Hyaluronoglucosaminidase / Q000037:antagonists & inhibitors; D019686:Lamiaceae / Q000737:chemistry*; D056785:Medicine, Mongolian Traditional; D008986:Mongolia; D039821:Monoterpenes / Q000302:isolation & purification*; D010851:Picrates / Q000737:chemistry; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000302:isolation & purification; D010946:Plants, Medicinal; D020005:Propanols / Q000302:isolation & purification*
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D047309:Flavones; D006027:Glycosides; D039821:Monoterpenes; D010851:Picrates; D010936:Plant Extracts; D020005:Propanols; C439395:1-phenylpropanol; C004931:1,1-diphenyl-2-picrylhydrazyl; D006821:Hyaluronoglucosaminidase; C023717:acacetin
keywords: DPPH radical scavenging activity; Dracocephalum foetidum; Hyaluronidase inhibitory activity; Lamiaceae; Limonene glycoside; Phenylpropanoid