title: Efficacy of in-feed preparations of an anticoccidial, multienzyme, prebiotic, probiotic, and herbal essential oil mixture in healthy and Eimeria spp.-infected broilers.
abstract: The efficacies of 5 widely used dietary supplements were investigated on performance indices, fecal oocyst excretion, lesion score, and intestinal tract measurements in healthy and Eimeria spp.-infected birds by using a comparative model. This study included 2,400 sexed Ross 308 broiler chicks that were equally divided in 2 groups: the infected group, experimentally infected with oocysts of mixed Eimeria spp. at 14 d of age, and the healthy controls. The birds in both groups were further divided equally into 6 groups, of which one was fed a basal diet and served as control without treatment and the other 5 served as experimental treatments. These 5 groups were fed 5 diets containing preparations of 60 mg/kg of anticoccidial salinomycin (SAL), 1 g/kg of multienzyme (ENZ), 1 g/kg of probiotic (PRO), 1 g/kg of prebiotic (PRE), and 40 mg/kg of an herbal essential oil mixture (EOM). Body weight gain and feed conversion ratio (FCR) showed significant improvement in the infected animals, which indicates that dietary supplemental regimens with SAL, ENZ, PRO, and PRE initiated in 1-d-old chicks reduced adverse effects after challenge with coccidiosis; however, chicks that were administered EOM failed to show such improvement. Uninfected chickens showed significant improvement in FCR with supplements SAL, PRE, and EOM, which signifies significant (P < 0.01) infection by supplement interactions for BW gain and FCR. In the infected group, all of the supplements reduced the severity of coccidiosis lesions (P < 0.01) induced by mixed Eimeria spp. through the middle and lower regions of the small intestines, whereas supplementation with SAL or EOM alone was effective (P < 0.01) in reducing oocyst excretion compared with the control treatment. The data indicated that use of these subtherapeutically efficacious supplements (except EOM) in broiler production can lessen the depression in growth due to coccidial challenge.
authors.affiliation: Poultry Research Institute,09600 Erbeyli, Aydın, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Bozkurt
authors.forename: N
authors.initials: N
authors.lastname: Aysul
authors.forename: K
authors.initials: K
authors.lastname: Küçükyilmaz
authors.forename: S
authors.initials: S
authors.lastname: Aypak
authors.forename: G
authors.initials: G
authors.lastname: Ege
authors.forename: A U
authors.initials: AU
authors.lastname: Catli
authors.forename: H
authors.initials: H
authors.lastname: Aksit
authors.forename: F
authors.initials: F
authors.lastname: Cöven
authors.forename: K
authors.initials: K
authors.lastname: Seyrek
authors.forename: M
authors.initials: M
authors.lastname: Cinar
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000818:Animals; D002645:Chickens / Q000254:growth & development; D003048:Coccidiosis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D003049:Coccidiostats / Q000008:administration & dosage / Q000494:pharmacology*; D004032:Diet / Q000662:veterinary; D019587:Dietary Supplements / Q000032:analysis; D004539:Eimeria / Q000502:physiology; D004798:Enzymes / Q000008:administration & dosage / Q000494:pharmacology; D005243:Feces / Q000469:parasitology; D005260:Female; D007422:Intestines / Q000187:drug effects / Q000469:parasitology / Q000473:pathology; D007476:Ionophores / Q000008:administration & dosage / Q000494:pharmacology; D008297:Male; D009822:Oils, Volatile / Q000008:administration & dosage / Q000494:pharmacology; D033661:Oocysts / Q000502:physiology; D011201:Poultry Diseases / Q000188:drug therapy* / Q000469:parasitology; D056692:Prebiotics / Q000032:analysis; D019936:Probiotics / Q000008:administration & dosage / Q000494:pharmacology; D011714:Pyrans / Q000008:administration & dosage / Q000494:pharmacology*; D015430:Weight Gain / Q000187:drug effects; D000095662:Polyether Polyketides
chemical_list: D003049:Coccidiostats; D004798:Enzymes; D007476:Ionophores; D009822:Oils, Volatile; D056692:Prebiotics; D011714:Pyrans; C010327:salinomycin; D000095662:Polyether Polyketides
keywords: anticoccidial; essential oil; multienzyme; prebiotic; probiotic