title: A new modified sesquiterpene glycoside from Cupressus chengiana.
abstract: A new sesquiterpene glycoside, cupressusoside (1), and five known compounds were isolated from the 70% aqueous ethanol extract of the branches and leaves of Cupressus chengiana. Their structures were elucidated by using spectroscopic methods. All the isolates expressed no remarkable cytotoxic activity against colon carcinoma (HCT-8) and breast cancer (MCF-7) cell lines, with IC50>40 mg/mL.
authors.affiliation: a Ethnic Pharmaceutical Institute, Southwest University for Nationalities , Sichuan, Chengdu 610041 , P.R. China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Lin
authors.forename: Rong-Jiao
authors.initials: RJ
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Brian D
authors.initials: BD
authors.lastname: McGarvey
authors.forename: Hai-Feng
authors.initials: HF
authors.lastname: Wu
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Wang
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029781:Cupressus / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D020128:Inhibitory Concentration 50; D061986:MCF-7 Cells; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D012717:Sesquiterpenes; C000591761:cupressusoside
keywords: Cupressus chengiana; cytotoxic activities; sesquiterpene