title: Laboratory examination in nerve agent intoxication.
abstract: Diagnosis of nerve agent intoxication is based on anamnestic data, clinical signs and laboratory examination. For acute poisoning, cholinesterase activity in the blood (erythrocyte AChE, plasma/serum BuChE) is sensitive, simple and most frequent laboratory examination performed in biochemical laboratories. Specialized examinations to precise treatment (reactivation test) or to make retrospective diagnosis (fluoride induced reactivation etc.) can be conducted. Other sophisticated methods are available, too.
authors.affiliation: University of Defence, Department of Toxicology, Faculty of Military Health Sciences, Hradec Králové, Czech Republic. bajgar@pmfhk.cz
authors.forename: Jirí
authors.initials: J
authors.lastname: Bajgar
mesh_terms: D002619:Chemical Warfare Agents / Q000737:chemistry / Q000494:pharmacology / Q000506:poisoning*; D002802:Cholinesterases / Q000378:metabolism; D019411:Clinical Laboratory Techniques; D006801:Humans; D062025:Organophosphate Poisoning / Q000175:diagnosis*
chemical_list: D002619:Chemical Warfare Agents; D002802:Cholinesterases