title: Management of neonatal herpes simplex virus infection and exposure.
abstract: Neonatal herpes simplex virus (HSV) infections are rare but are associated with significant morbidity and mortality. Advances in diagnostic modalities to identify these infants, as well as the development of safe and effective antiviral therapy, have revolutionised the management of affected infants. This review will summarise the epidemiology of neonatal HSV infections and discuss the management of infants with HSV exposure and infection.
authors.affiliation: Division of Pediatric Infectious Diseases, The University of Alabama at Birmingham, , Birmingham, Alabama, USA.
authors.forename: Swetha G
authors.initials: SG
authors.lastname: Pinninti
authors.forename: David W
authors.initials: DW
authors.lastname: Kimberlin
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage*; D005260:Female; D006561:Herpes Simplex / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000635:transmission; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D018811:Maternal Exposure / Q000706:statistics & numerical data*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology; D011379:Prognosis
chemical_list: D000998:Antiviral Agents
keywords: PCR; acyclovir; genital herpes; neonatal herpes