title: Evaluation of the effect of Lake Hévíz thermal mineral water in patients with osteoarthritis of the knee: a randomized, controlled, single-blind, follow-up study.
abstract: BACKGROUND
  Osteoarthritis is the most frequent joint disease and is a leading cause of pain and locomotor disability in elderly people. The treatment of osteoarthritis includes non-pharmacological, pharmacological, and surgical therapies. Silver level evidence has been found concerning balneotherapy in osteoarthritis.
  
  
  OBJECTIVE
  The aim of this study was to evaluate how Lake Hévíz thermal mineral water therapy influences pain, knee function, and quality of life in patients with knee osteoarthritis, compared to the control group.
  
  
  METHODS
  randomized, controlled, single-blind, follow-up study.
  
  
  METHODS
  Spa Hévíz and St. Andrew Hospital for Rheumatic Diseases
  
  
  METHODS
  This study included 77 outpatients between 45 and 75 years of age with mild to moderate osteoarthritis of the knee meeting the American College of Rheumatology classification criteria.
  
  
  METHODS
  Patients were randomized into two groups. In group I (n = 38), subjects bathed in Lake Hévíz and in group II (N.=39), patients were treated in a pool full of tap water. Water temperature was 34 °C for both groups. Participants underwent 30-minute therapy sessions, five times a week for three weeks. Outcome measures were pain visual analogue scale scores, active flexion degree, knee circumference, stair-climb time, Western Ontario and McMaster Universities osteoarthritis index (WOMAC), and EuroQoL Group 5-Dimension Self-Report Questionnaire score (EQ-5D). Study parameters were recorded at baseline, immediately after treatment, and after 15 weeks.
  
  
  RESULTS
  Comparison of the two groups revealed a statistically significant difference in pain visual analogue scale scores (P<0.01), active flexion degree (P<0.01), physical function components of WOMAC (P<0.05), and EQ-5D scores (P<0.05) even after 15 weeks.
  
  
  CONCLUSIONS
  Balneotherapy improved pain, function as well as the quality of life in patients with knee osteoarthritis.
  
  
  CONCLUSIONS
  Balneotherapy is a potentially useful treatment modality for patients with knee osteoarthritis.
authors.affiliation: St. Andrew Hospital for Rheumatic Diseases Hévíz, Hungary - bender@mail.datanet.hu.
authors.forename: Á
authors.initials: Á
authors.lastname: Kulisch
authors.forename: Á
authors.initials: Á
authors.lastname: Benkö
authors.forename: A
authors.initials: A
authors.lastname: Bergmann
authors.forename: N
authors.initials: N
authors.lastname: Gyarmati
authors.forename: Horváth
authors.initials: H
authors.lastname: Horváth
authors.forename: Á
authors.initials: Á
authors.lastname: Kránicz
authors.forename: Z S
authors.initials: ZS
authors.lastname: Mándó
authors.forename: Á
authors.initials: Á
authors.lastname: Matán
authors.forename: A
authors.initials: A
authors.lastname: Németh
authors.forename: E
authors.initials: E
authors.lastname: Szakál
authors.forename: D
authors.initials: D
authors.lastname: Szántó
authors.forename: L
authors.initials: L
authors.lastname: Szekeres
authors.forename: T
authors.initials: T
authors.lastname: Bender
mesh_terms: D000368:Aged; D001452:Balneology / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D060106:Lakes; D008297:Male; D008875:Middle Aged; D008900:Mineral Waters / Q000627:therapeutic use*; D020370:Osteoarthritis, Knee / Q000534:rehabilitation*; D011788:Quality of Life; D016037:Single-Blind Method; D016896:Treatment Outcome
chemical_list: D008900:Mineral Waters