title: Comparison of serum androgens and endometrial thickness in obese and non-obese postmenopausal women.
abstract: OBJECTIVE
  In this study, we investigated whether serum androgen levels and endometrial thickness differed in obese and non-obese women.
  
  
  METHODS
  Thirtytwo non-obese (BMI <30) and 48 obese (BMI ≥ 30) women were enrolled. Blood samples were analyzed for testosterone, free testosterone, androstenedione, DHEAS, and SHBG, and transvaginal ultrasonography was performed.
  
  
  RESULTS
  Obese women had significantly higher free testosterone and endometrial thickness and significantly lower SHBG. Eight of 17 women with endometrial thickness >5 mm had significant pathology.
  
  
  CONCLUSIONS
  These results suggest that obesity may be a risk factor for endometrial carcinoma and other pathologies in post-menopausal women through an action on androgen concentrations.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey.
authors.forename: Ilker İnan
authors.initials: Iİ
authors.lastname: Arıkan
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey.
authors.forename: Aykut
authors.initials: A
authors.lastname: Barut
authors.affiliation: Department of Gynecology and Obstetrics, Faculty of Medicine, Kahramanmaraş Sütcü İmam University, Kahramanmaraş, Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Arıkan
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey.
authors.forename: Müge
authors.initials: M
authors.lastname: Harma
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey.
authors.forename: Mehmet İbrahim
authors.initials: Mİ
authors.lastname: Harma
authors.affiliation: Department of Gynecology and Obstetrics, Faculty of Medicine, Maltepe University, İstanbul, Turkey.
authors.forename: Serpil
authors.initials: S
authors.lastname: Bozkurt
keywords: Serum androgene; endometrial thickness; obesity; post-menopause