title: Initial experience with dexmedetomidine for dental sedation in children.
abstract: Sedation of uncooperative children for dental treatment is difficult since treatment is mainly carried out inside the oral cavity. Dexmedetomidine (DEX), recently introduced into clinical practice, has little influence on respiratory system even at high doses. We present cases of patients who underwent dental treatment under sedation using DEX infusion. DEX at a dose of 1 microg/kg was administered over 10 min after intravenous cannulation. DEX was infused to maintain sedation level within the range of the Observer's Assessment of Alertness and Sedation (OAA/S) scale 3- 4 throughout dental treatments. They were successfully treated under DEX sedation without any complications. Their uncooperative behaviors were successfully managed under DEX sedation.
authors.affiliation: Department of Pediatric Dentistry, Seoul National University Hospital, Seoul, Republic of Korea.
authors.forename: Hyo Sun
authors.initials: HS
authors.lastname: Kim
authors.affiliation: Department of Pediatric Dentistry, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul, Republic of Korea.
authors.forename: Jung-Wook
authors.initials: JW
authors.lastname: Kim
authors.affiliation: Department of Pediatric Dentistry, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul, Republic of Korea.
authors.forename: Ki-Taeg
authors.initials: KT
authors.lastname: Jang
authors.affiliation: Department of Pediatric Dentistry, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul, Republic of Korea.
authors.forename: Sang-Hoon
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Department of Pediatric Dentistry, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul, Republic of Korea.
authors.forename: Chong-Chul
authors.initials: CC
authors.lastname: Kim
authors.affiliation: Department of Pediatric Dentistry, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul, Republic of Korea.
authors.forename: Teo Jeon
authors.initials: TJ
authors.lastname: Shin
mesh_terms: D000762:Anesthesia Recovery Period; D001794:Blood Pressure / Q000187:drug effects; D002648:Child; D002652:Child Behavior / Q000187:drug effects*; D002675:Child, Preschool; D054810:Deep Sedation / Q000379:methods; D019140:Dental Care for Children / Q000379:methods*; D020927:Dexmedetomidine / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000494:pharmacology*; D007262:Infusions, Intravenous; D008297:Male; D056152:Respiratory Rate / Q000187:drug effects
chemical_list: D006993:Hypnotics and Sedatives; D020927:Dexmedetomidine