title: The neural basis of sublexical speech and corresponding nonspeech processing: a combined EEG-MEG study.
abstract: We addressed the neural organization of speech versus nonspeech sound processing by investigating preattentive cortical auditory processing of changes in five features of a consonant-vowel syllable (consonant, vowel, sound duration, frequency, and intensity) and their acoustically matched nonspeech counterparts in a simultaneous EEG-MEG recording of mismatch negativity (MMN/MMNm). Overall, speech-sound processing was enhanced compared to nonspeech sound processing. This effect was strongest for changes which affect word meaning (consonant, vowel, and vowel duration) in the left and for the vowel identity change in the right hemisphere also. Furthermore, in the right hemisphere, speech-sound frequency and intensity changes were processed faster than their nonspeech counterparts, and there was a trend for speech-enhancement in frequency processing. In summary, the results support the proposed existence of long-term memory traces for speech sounds in the auditory cortices, and indicate at least partly distinct neural substrates for speech and nonspeech sound processing.
authors.affiliation: Cognitive Brain Research Unit, Institute of Behavioral Sciences, P.O. Box 9, 00014 University of Helsinki, Finland. Electronic address: soila.kuuluvainen@helsinki.fi.
authors.forename: Soila
authors.initials: S
authors.lastname: Kuuluvainen
authors.affiliation: BioMag Laboratory, Hospital District of Helsinki and Uusimaa, HUS Medical Imaging Center, P.O. Box 340, 00029 HUS, Helsinki University Central Hospital, Helsinki, Finland.
authors.forename: Päivi
authors.initials: P
authors.lastname: Nevalainen
authors.affiliation: Cognitive Brain Research Unit, Institute of Behavioral Sciences, P.O. Box 9, 00014 University of Helsinki, Finland; Laboratory of Neurophysiology, Mental Health Research Centre, Russian Academy of Medical Sciences, Kashirskoe sh. 34, 115522 Moscow, Russia; Centre of Neurobiological Diagnostics, Moscow State University of Psychology and Education, Sretenka 29, 127051 Moscow, Russia.
authors.forename: Alexander
authors.initials: A
authors.lastname: Sorokin
authors.affiliation: Cognitive Brain Research Unit, Institute of Behavioral Sciences, P.O. Box 9, 00014 University of Helsinki, Finland; University Of Washington, Institute for Learning and Brain Sciences, Seattle, Washington, United States of America.
authors.forename: Maria
authors.initials: M
authors.lastname: Mittag
authors.affiliation: Cognitive Brain Research Unit, Institute of Behavioral Sciences, P.O. Box 9, 00014 University of Helsinki, Finland; Center of Excellence in Interdisciplinary Music Research, Department of Music, P.O. Box 35, 40014 University of Jyväskylä, Finland.
authors.forename: Eino
authors.initials: E
authors.lastname: Partanen
authors.affiliation: Cognitive Brain Research Unit, Institute of Behavioral Sciences, P.O. Box 9, 00014 University of Helsinki, Finland; Center of Excellence in Interdisciplinary Music Research, Department of Music, P.O. Box 35, 40014 University of Jyväskylä, Finland.
authors.forename: Vesa
authors.initials: V
authors.lastname: Putkinen
authors.affiliation: Cognitive Brain Research Unit, Institute of Behavioral Sciences, P.O. Box 9, 00014 University of Helsinki, Finland; Center of Excellence in Interdisciplinary Music Research, Department of Music, P.O. Box 35, 40014 University of Jyväskylä, Finland.
authors.forename: Miia
authors.initials: M
authors.lastname: Seppänen
authors.affiliation: BioMag Laboratory, Hospital District of Helsinki and Uusimaa, HUS Medical Imaging Center, P.O. Box 340, 00029 HUS, Helsinki University Central Hospital, Helsinki, Finland.
authors.forename: Seppo
authors.initials: S
authors.lastname: Kähkönen
authors.affiliation: Cognitive Brain Research Unit, Institute of Behavioral Sciences, P.O. Box 9, 00014 University of Helsinki, Finland; CICERO Learning, Institute of Behavioral Sciences, P.O. Box 9, 00014 University of Helsinki, Finland.
authors.forename: Teija
authors.initials: T
authors.lastname: Kujala
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001303:Auditory Cortex / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology; D004192:Discrimination, Psychological / Q000502:physiology; D004569:Electroencephalography / Q000379:methods; D005072:Evoked Potentials, Auditory; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008297:Male; D057567:Memory, Long-Term / Q000502:physiology; D010700:Phonetics; D011930:Reaction Time / Q000502:physiology; D012016:Reference Values; D012660:Semantics; D013067:Speech Perception / Q000502:physiology*; D055815:Young Adult
keywords: Auditory cortex; EEG; MEG; MMN; MMNm; Nonspeech; Speech