title: Comparing Electrolytes in Prestorage Leukocyte-Reduced Packed Cell versus Unfiltered Packed Cell.
abstract: BACKGROUND
  Blood transfusion is associated with side effects caused by residual leukocytes in blood and blood components. Using leukodepleted blood components can decrease some of these adverse effects. Among the various methods to remove leukocytes in blood components, prestorage leukoreduction has been most efficient, but the evidence of clinical side effects awaits further studies. We evaluated changes of electrolytes in prestorage leukocyte-reduced red blood cells.
  
  
  METHODS
  In this case-control study, one hundred twenty eight packed cells were studied: 64 unfiltered packed cells and 64 prestorage filtered packed cell. Two groups were matched as sex and age. Electrolytes such as Calcium, Sodium, and Potassium of two groups were measured, and compared during preparation.
  
  
  RESULTS
  In this study, mean of Calcium in unfiltered and filtered group were 6.16±1.09 mg/dl and 5.57±2.21 mg/dl, respectively (P-value<0.055). Mean of Sodium in unfiltered group also was 155.91+/-9.51meq/l and in filtered group, 153.05+/-13.21meq/l (P-value<0.163), and mean of Potassium in unfiltered group was 5.01+/-1.72 meq/l and in filtered group, 7.42+/-2.45meq/l (P-value<0.001).
  
  
  CONCLUSIONS
  Releasing of Potassium during preparation of prestorage leukoreduction can cause increased Potassium level and hemoglobin concentration changes in prestorage filtered packed cell.
authors.affiliation: MSc of Biochemistry, Payam nor University, Taft, Yazd, Iran.
authors.forename: L
authors.initials: L
authors.lastname: Fallahi
authors.affiliation: Internal Medicine. Hematology, Oncology and Genetics Research Center Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
authors.forename: R
authors.initials: R
authors.lastname: Ghiliyan
authors.affiliation: Department of Pediatrics, Hematology, Oncology and Genetics Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
authors.forename: A
authors.initials: A
authors.lastname: Hashemi
authors.affiliation: Blood Transfusion Center, Yazd, Iran.
authors.forename: A
authors.initials: A
authors.lastname: Fatemi
authors.affiliation: MSc of Biochemistry, Payam nor University, Taft, Yazd, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Saeedi
keywords: Blood Transfusion; Electrolytes; Leukocytes