title: The osteoplastic effectiveness of the implants made of mesh titanium nickelide constructs.
abstract: The purpose of the work was to study the features of reparative osteogenesis for filling the defect of tubular bone under implantation of mesh titanium nickelide constructs. Tibial fenestrated defect was modeled experimentally in 30 Wistar pubertal rats, followed by implant intramedullary insertion. The techniques of radiography, scanning electron microscopy and X-ray electron probe microanalysis were used. The mesh implant of titanium nickelide has been established to possess biocompatibility, osteoconductive and osteoinductive properties, the zone of osteogenesis and angiogenesis is created around it, bone cover is formed. Osteointegration of the implant occurs early, by 7 days after surgery, and by 30 days after surgery organotypical re-modelling of the regenerated bone takes place, as well as the defect is filled with lamellar bone tissue by the type of bone wound primary adhesion. By 30 days after surgery mineral content of the regenerated bone tissue approximates to the composition of intact cortex mineral phase.
authors.affiliation: Laboratory of Morphology, Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), M. Ul'ianova Street, 6.Kurgan, 640014, Russia.
authors.forename: Iurii
authors.initials: I
authors.lastname: Mikhailovich Irianov
authors.affiliation: Laboratory of Purulent Osteology and Limb Defect Filling, RISC RTO, M. Ul'ianova Street, 6. Kurgan, 640014, Russia.
authors.forename: Olga
authors.initials: O
authors.lastname: Vladimirovna Diuriagina
authors.affiliation: Department of Orthopaedics, Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), M. Ulianova Street, 6.Kurgan, 640014, Russia.
authors.forename: Tatiana
authors.initials: T
authors.lastname: Iurevna Karaseva
authors.affiliation: Department of Orthopaedics, Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), M. Ulianova Street, 6.Kurgan, 640014, Russia.
authors.forename: Evgenii
authors.initials: E
authors.lastname: Anatolevich Karasev
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D016723:Bone Remodeling; D018786:Bone Substitutes / Q000737:chemistry*; D001842:Bone and Bones; D004577:Electron Probe Microanalysis; D005260:Female; D006253:Haversian System / Q000166:cytology; D020007:Implants, Experimental; D008297:Male; D018919:Neovascularization, Physiologic; D009532:Nickel / Q000737:chemistry*; D016348:Osseointegration / Q000502:physiology; D010006:Osteoblasts / Q000166:cytology; D010012:Osteogenesis; D051381:Rats; D017208:Rats, Wistar; D013977:Tibia / Q000473:pathology; D014025:Titanium / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; C040654:titanium nickelide; D009532:Nickel; D014025:Titanium