title: The impact of a modified cutting flute implant design on osseointegration.
abstract: Information concerning the effects of the implant cutting flute design on initial stability and its influence on osseointegration in vivo is limited. This study evaluated the early effects of implants with a specific cutting flute design placed in the sheep mandible. Forty-eight dental implants with two different macro-geometries (24 with a specific cutting flute design - Blossom group; 24 with a self-tapping design - DT group) were inserted into the mandibular bodies of six sheep; the maximum insertion torque was recorded. Samples were retrieved and processed for histomorphometric analysis after 3 and 6 weeks. The mean insertion torque was lower for Blossom implants (P<0.001). No differences in histomorphometric results were observed between the groups. At 3 weeks, P=0.58 for bone-to-implant contact (BIC) and P=0.52 for bone area fraction occupied (BAFO); at 6 weeks, P=0.55 for BIC and P=0.45 for BAFO. While no histomorphometric differences were observed, ground sections showed different healing patterns between the implants, with better peri-implant bone organization around those with the specific cutting flute design (Blossom group). Implants with the modified cutting flute design had a significantly reduced insertion torque compared to the DT implants with a traditional cutting thread, and resulted in a different healing pattern.
authors.affiliation: Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden. Electronic address: ryo.jimbo@mah.se.
authors.forename: R
authors.initials: R
authors.lastname: Jimbo
authors.affiliation: Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, USA.
authors.forename: N
authors.initials: N
authors.lastname: Tovar
authors.affiliation: Department of Dentistry, UNIGRANRIO, Duque de Caxias, RJ, Brazil.
authors.forename: C
authors.initials: C
authors.lastname: Marin
authors.affiliation: Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, USA.
authors.forename: H S
authors.initials: HS
authors.lastname: Teixeira
authors.affiliation: Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, USA.
authors.forename: R B
authors.initials: RB
authors.lastname: Anchieta
authors.affiliation: Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, USA.
authors.forename: L M
authors.initials: LM
authors.lastname: Silveira
authors.affiliation: Department of Epidemiology, New York University College of Dentistry, New York, USA.
authors.forename: M N
authors.initials: MN
authors.lastname: Janal
authors.affiliation: Department of Periodontology, Dental Research Division and Oral Implantology Clinic, Guarulhos University, Guarulhos, SP, Brazil.
authors.forename: J A
authors.initials: JA
authors.lastname: Shibli
authors.affiliation: Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, USA; Department of Periodontology and Implant Dentistry, New York University College of Dentistry, New York, USA.
authors.forename: P G
authors.initials: PG
authors.lastname: Coelho
mesh_terms: D000818:Animals; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D017267:Dental Prosthesis Design; D003799:Dental Stress Analysis; D008334:Mandible / Q000601:surgery; D023421:Models, Animal; D016348:Osseointegration / Q000502:physiology*; D012756:Sheep; D019415:Torque; D014945:Wound Healing / Q000502:physiology
chemical_list: D015921:Dental Implants
keywords: cutting flute design; histomorphometry; implants; insertion torque; macro-geometry; osseointegration; primary stability; secondary stability; thread design