title: Vaccines for Pseudomonas aeruginosa: a long and winding road.
abstract: Despite the recognition of Pseudomonas aeruginosa as an opportunistic pathogen, no vaccine against this bacteria has come to market. This review describes the current state-of-the-art in vaccinology for this bacterium. This includes a discussion of those at risk for infection, the types of vaccines and the approaches for empirical and targeted antigen selection under development, as well as a perspective on where the field should go. In addition, the challenges in developing a vaccine for those individuals at risk are discussed.
authors.affiliation: Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Gregory P
authors.initials: GP
authors.lastname: Priebe
authors.forename: Joanna B
authors.initials: JB
authors.lastname: Goldberg
mesh_terms: D055808:Drug Discovery / Q000379:methods* / Q000639:trends; D006801:Humans; D011552:Pseudomonas Infections / Q000276:immunology* / Q000517:prevention & control*; D054406:Pseudomonas Vaccines / Q000276:immunology* / Q000302:isolation & purification*; D011550:Pseudomonas aeruginosa / Q000276:immunology*
chemical_list: D054406:Pseudomonas Vaccines