title: Glomerulopathy in adult recipients of pediatric kidneys.
abstract: To compare "for cause" renal biopsies (bx) from adult recipients of pediatric-donor kidneys (PDK) versus adult-donor kidneys (ADKs), we reviewed 103 graft bx from 50 PDK recipients and 85 bx from 49 ADK recipients. PDK bx displayed more frequent glomerular pathology with immune complex-mediated glomerulonephritis present in 11/103 PDK versus 1/85 ADK (p < 0.05). In 15/103 PDK bx and 1/85 ADK (p = 0.001), the association of glomerular sclerosis, expanded mesangium, and halo of prominent podocytes by light microscopy, and ultrastructural glomerular basement membrane lamellation, configured a characteristic glomerulopathy.
authors.affiliation: Debakey Scholars Program, Tulane University School of Medicine , New Orleans, LA , USA and.
authors.forename: Hae Yoon Grace
authors.initials: HY
authors.lastname: Choung
authors.forename: Suzanne
authors.initials: S
authors.lastname: Meleg-Smith
mesh_terms: D000328:Adult; D000367:Age Factors; D064591:Allografts; D002648:Child; D006801:Humans; D007674:Kidney Diseases / Q000453:epidemiology* / Q000628:therapy; D016030:Kidney Transplantation; D012189:Retrospective Studies; D014019:Tissue Donors