title: Dielectrophoretic response of DNA shows different conduction mechanisms for poly(dG)-poly(dC) and poly(dA)-Poly(dT) in solution.
abstract: Although the subject of some scrutiny over the years, the mechanism of conduction in DNA has not yet been resolved, with competing theories suggesting either electronic and ionic conduction mechanisms. In this paper we use dielectrophoresis to determine the electrical properties of poly(dG)-poly(dC) (GC) and poly(dA)-poly(dT) (AT) DNA in solution. The molecules show different conduction mechanisms; GC DNA exhibits conduction primarily through the molecule, whereas in AT DNA conduction through the counterion cloud surrounding the molecule in solution is more significant.
authors.forename: A S
authors.initials: AS
authors.lastname: Mohamad
authors.forename: J C G
authors.initials: JC
authors.lastname: Jeynes
authors.forename: M P
authors.initials: MP
authors.lastname: Hughes
mesh_terms: D004247:DNA / Q000737:chemistry*; D004553:Electric Conductivity; D004566:Electrodes; D011089:Polydeoxyribonucleotides / Q000737:chemistry*; D012996:Solutions
chemical_list: D011089:Polydeoxyribonucleotides; D012996:Solutions; C016681:poly(dG).poly(dC); C084838:polydeoxyadenylic acid-polythymidylic acid; D004247:DNA