title: Cervical cancer screening and analysis of potential risk factors in 43,567 women in Zhongshan, China.
abstract: OBJECTIVE
  The objective of this study was to establish a program model for use in wide-spread cervical cancer screening.
  
  
  METHODS
  Cervical cancer screening was conducted in Zhongshan city in Guangdong province, China through a coordinated network of multiple institutes and hospitals. A total of 43,567 women, 35 to 59 years of age, were screened during regular gynecological examinations using the liquid-based ThinPrep cytology test (TCT). Patients who tested positive were recalled for further treatment.
  
  
  RESULTS
  The TCT-positive rate was 3.17%, and 63.4% of these patients returned for follow-up. Pathology results were positive for 30.5% of the recalled women. Women who were younger than 50 years of age, urban dwelling, low-income, had a history of cervical disease, began having sex before 20 years of age, or had sex during menstruation, were at elevated risk for a positive TCT test. The recall rate was lower in women older than 50 years of age, urban dwelling, poorly educated, and who began having sex early. A higher recall rate was found in women 35 years of age and younger, urban dwelling, women who first had sex after 24 years of age, and women who had sex during menstruation. The positive pathology rate was higher in urban women 50 years of age and younger and women who tested positive for human papillomavirus.
  
  
  CONCLUSIONS
  An effective model for large-scale cervical cancer screening was successfully established. These results suggest that improvements are needed in basic education regarding cervical cancer screening for young and poorly educated women. Improved outreach for follow-up is also necessary to effectively control cervical cancer.
authors.affiliation: Department of Obstetrics and Gynecology and Department of Pathology, BaoAi Hospital, Southern Medical University Affiliated Hospital, Zhongshan, China E-mail : 340382761@qq.com.
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.forename: Yan-Hong
authors.initials: YH
authors.lastname: Yu
authors.forename: Keng
authors.initials: K
authors.lastname: Shen
authors.forename: Lin
authors.initials: L
authors.lastname: Xiao
authors.forename: Feng
authors.initials: F
authors.lastname: Luan
authors.forename: Xian-Jun
authors.initials: XJ
authors.lastname: Mi
authors.forename: Xiao-Min
authors.initials: XM
authors.lastname: Zhang
authors.forename: Li-Hua
authors.initials: LH
authors.lastname: Fu
authors.forename: Ang
authors.initials: A
authors.lastname: Chen
authors.forename: Xiang
authors.initials: X
authors.lastname: Huang
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000209:etiology; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000209:etiology; D002681:China; D055088:Early Detection of Cancer; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000209:etiology; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis* / Q000209:etiology