title: Potential for improved glycemic control with dietary Momordica charantia in patients with insulin resistance and pre-diabetes.
abstract: Bitter Melon (Momordica charantia) is a widely used traditional remedy for hyperglycemia. While the medicinal properties of this plant have been studied extensively using in vitro and animal models, the clinical efficacy and safety in humans is largely unknown. This review discusses the benefits and limitations of bitter melon supplementation in the context of epidemic levels of insulin resistance and pre-diabetes throughout the world.
authors.affiliation: East Carolina Heart Institute and the Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA. jimmy.efird@stanfordalumni.org.
authors.forename: Jimmy T
authors.initials: JT
authors.lastname: Efird
authors.affiliation: Adult Gerontological Nurse Practitioner Program, School of Nursing, University of North Carolina at Greensboro, Greensboro, NC 27402, USA. y_choi6@uncg.edu.
authors.forename: Yuk Ming
authors.initials: YM
authors.lastname: Choi
authors.affiliation: Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA 22908, USA. sd2wf@virginia.edu.
authors.forename: Stephen W
authors.initials: SW
authors.lastname: Davies
authors.affiliation: Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA. mehras@ecu.edu.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Mehra
authors.affiliation: Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA. andersonet@ecu.edu.
authors.forename: Ethan J
authors.initials: EJ
authors.lastname: Anderson
authors.affiliation: Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA. katungal10@students.ecu.edu.
authors.forename: Lalage A
authors.initials: LA
authors.lastname: Katunga
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000187:drug effects; D006801:Humans; D007333:Insulin Resistance; D029777:Momordica charantia; D008517:Phytotherapy; D028321:Plant Preparations / Q000494:pharmacology / Q000627:therapeutic use*; D011236:Prediabetic State / Q000188:drug therapy*; D016032:Randomized Controlled Trials as Topic
chemical_list: D001786:Blood Glucose; D028321:Plant Preparations