title: Vitamin, mineral, and multivitamin supplements for the primary prevention of cardiovascular disease and cancer: U.S. Preventive services Task Force recommendation statement.
abstract: METHODS
  Update of the 2003 U.S. Preventive Services Task Force (USPSTF) recommendation on vitamin supplementation to prevent cardiovascular disease and cancer.
  
  
  METHODS
  The USPSTF reviewed the evidence on the efficacy of multivitamin or mineral supplements in the general adult population for the prevention of cardiovascular disease and cancer.
  
  
  METHODS
  This recommendation applies to healthy adults without special nutritional needs (typically aged 50 years or older). It does not apply to children, women who are pregnant or may become pregnant, or persons who are chronically ill or hospitalized or have a known nutritional deficiency.
  
  
  CONCLUSIONS
  The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of multivitamins for the prevention of cardiovascular disease or cancer. (I statement). The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of single- or paired-nutrient supplements (except β-carotene and vitamin E) for the prevention of cardiovascular disease or cancer. (I statement). The USPSTF recommends against β-carotene or vitamin E supplements for the prevention of cardiovascular disease or cancer. (D recommendation).
authors.forename: Virginia A
authors.initials: VA
authors.lastname: Moyer
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D019587:Dietary Supplements / Q000009:adverse effects; D006801:Humans; D008875:Middle Aged; D008903:Minerals / Q000009:adverse effects / Q000627:therapeutic use*; D009369:Neoplasms / Q000517:prevention & control*; D011322:Primary Prevention; D012106:Research; D018570:Risk Assessment; D014810:Vitamin E / Q000627:therapeutic use; D014815:Vitamins / Q000009:adverse effects / Q000627:therapeutic use*; D019207:beta Carotene / Q000627:therapeutic use
chemical_list: D008903:Minerals; D014815:Vitamins; D019207:beta Carotene; D014810:Vitamin E