title: Sister Mary Joseph nodule: a tip of an iceberg.
abstract: A Sister Mary Joseph nodule represents a cutaneous metastasis into the umbilicus. This clinical sign of intra-abdominal malignancy is frequently overlooked or misinterpreted by both patients and their physicians. We report 4 patients with a Sister Mary Joseph nodule. The umbilical metastases appeared sonographically as hypoechoic masses with irregular margins and small internal hyperechoic foci. Further evaluation revealed disseminated malignancy, and the umbilical nodule was just "a tip of an iceberg."
authors.affiliation: Department of General Gastroenterological, and Oncological Surgery, Medical University of Warsaw, Ulica Banacha 1A, 02-097 Warsaw, Poland. mwronski@vp.pl.
authors.forename: Marek
authors.initials: M
authors.lastname: Wronski
authors.forename: Andrzej
authors.initials: A
authors.lastname: Klucinski
authors.forename: Ireneusz W
authors.initials: IW
authors.lastname: Krasnodebski
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging*; D058288:Sister Mary Joseph's Nodule / Q000000981:diagnostic imaging*; D012878:Skin Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D014463:Ultrasonography / Q000379:methods*; D014472:Umbilicus / Q000000981:diagnostic imaging*
keywords: Sister Mary Joseph nodule; gastrointestinal neoplasm; gastrointestinal ultrasound; sonography; umbilical metastasis