title: C-reactive protein and lipoprotein-a as markers of coronary heart disease in polycystic ovary syndrome.
abstract: OBJECTIVE
  The aim of this study was to investigate the risk factors of coronary heart disease, CRP and Lipoprotein-a in polycystic ovary syndrome patients.
  
  
  METHODS
  Prospectively collected data of polycystic ovary syndrome patients (n=62) and control group (n=40) were compared.
  
  
  RESULTS
  PCOS patients had higher HOMA-IR, CRP, DHEAS, free testosterone, FAI, LH and prolactin levels when compared to the control group. Lipoprotein-a levels did not differ between the groups. The obese PCOS group had statistically significantly higher fasting blood glucose, total cholesterol, triglyceride, free testosterone, insulin, CRP and HOMA-IR and statistically significantly lower HDL and SHBG when compared to normal weight PCOS persons. Fasting blood glucose, total cholesterol, LDL, SHBG, CRP, Lipoprotein-a, FSH, LH, TSH, DHEAS and prolactin levels did not differ between the normal weight and obese control groups.
  
  
  CONCLUSIONS
  CRP levels increase in polycystic ovary syndrome patients and can be used as a marker of coronary heart disease. Future studies can be directed at treatments to decrease CRP levels, including antiinflammatory treatments.
authors.affiliation: Department of Obstetrics and Gynecology, İstanbul Bilim University Avrupa Florence Nightingale Hospital, İstanbul, Turkey.
authors.forename: Nilgün
authors.initials: N
authors.lastname: Güdücü
authors.affiliation: Department of Obstetrics and Gynecology, İstanbul Bilim University Avrupa Florence Nightingale Hospital, İstanbul, Turkey.
authors.forename: Herman
authors.initials: H
authors.lastname: Işçi
authors.affiliation: Department of Obstetrics and Gynecology, İstanbul Bilim University Avrupa Florence Nightingale Hospital, İstanbul, Turkey.
authors.forename: Alin Başgül
authors.initials: AB
authors.lastname: Yiğiter
authors.affiliation: Department of Obstetrics and Gynecology, İstanbul Bilim University Avrupa Florence Nightingale Hospital, İstanbul, Turkey.
authors.forename: Ilkkan
authors.initials: I
authors.lastname: Dünder
keywords: CRP; Polycystic ovary syndrome; coronary heart disease; lipoprotein-a; obesity