title: Efficient synthesis strategies by application of transition metal-catalyzed carbene/nitrene insertions into C-H bonds.
abstract: Transition metal-catalyzed insertion of carbenes and nitrenes into C-H bonds has become a powerful tool for the construction of C-C and C-N bonds in the synthesis of complex natural products. In this Highlight, a selection of syntheses are detailed involving the implementation of C-H insertion reactions leading to strategies marked by improved efficiency.
authors.affiliation: ETH Zurich, Laboratory of Organic Chemistry, Wolfgang-Pauli-Strasse 10, 8093 Zurich, Switzerland. carreira@org.chem.ethz.ch.
authors.forename: Julian
authors.initials: J
authors.lastname: Egger
authors.forename: Erick M
authors.initials: EM
authors.lastname: Carreira
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D013237:Stereoisomerism; D028561:Transition Elements / Q000737:chemistry*
chemical_list: D001688:Biological Products; D028561:Transition Elements