title: [Meta-analysis of prognosis after surgical treatment in gastric cancer patients with liver metastasis].
abstract: OBJECTIVE
  To assess the value of gastric and hepatic surgical treatment in gastric cancer patients with liver metastasis and its prognostic implication.
  
  
  METHODS
  Literature search was performed in pubmed, Embase, Ovid, Springer-Link, Web of Science, CNKI, CBMdisc for clinical research published before March 2013 that compared gastrectomy alone to gastrectomy and hepatectomy. Inclusion criteria and exclusion criteria were performed. Quality assessment was based on NOS scale. Stata12.0 was used for statistical analysis.
  
  
  RESULTS
  Nine studies including 431 patients were enrolled for analysis, among whom 189 underwent gastrectomy and hepatectomy and 242 underwent gastrectomy alone. Gastrectomy and hepatectomy group had better survival(HR=0.50, 95%CI:0.34-0.72, z=3.66, P=0.000). There was a subgroup analysis. Gastrectomy with hepatectomy group had significant advantages in prognosis in four foreign studies(HR=0.28, 95%CI:0.18-0.44, z=5.77, P=0.000). There was no significant difference in five domestic studies (HR=0.74, 95%CI:0.55-1.00, z=1.95, P=0.051).
  
  
  CONCLUSIONS
  Gastrectomy and hepatectomy in gastric cancer patients with liver metastasis improves long-term survival in select patients.
authors.affiliation: Department of General Surgery, Chinese PLA General Hospital, Beijing 100853, China. chenlinbj@vip.sina.com.
authors.forename: Weisong
authors.initials: W
authors.lastname: Shen
authors.forename: Jiyang
authors.initials: J
authors.lastname: Li
authors.forename: Jianxin
authors.initials: J
authors.lastname: Cui
authors.forename: Hongqing
authors.initials: H
authors.lastname: Xi
authors.forename: Senfeng
authors.initials: S
authors.lastname: Liu
authors.forename: Bo
authors.initials: B
authors.lastname: Wei
authors.forename: Lin
authors.initials: L
authors.lastname: Chen
mesh_terms: D005743:Gastrectomy; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery; D011379:Prognosis; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery