title: Oral focal epithelial hyperplasia: report of three cases.
abstract: Focal epithelial hyperplasia or Heck's disease is an infrequent asymptomatic condition caused by human papillomavirus types 13 or 32 affecting the mucous membrane of the mouth and is commonly seen in young individuals. Firstly, it was described in Indians and Eskimos, but it exists in various populations. We present three cases of Heck's disease in an Afghan immigrant family group living in Iran that seem to have familial predominance. The disease was identified as oral focal epithelial hyperplasia on the basis of histopathologic and clinical findings. The lesions were reduced significantly after 4 months of good oral hygiene. Dentists should be familiar with the clinical manifestations of these types of lesions that affect the oral cavity. In fact, histopathologic assessment and clinical observation are necessary to establish the diagnosis.
authors.forename: Parichehr
authors.initials: P
authors.lastname: Ghalayani
authors.forename: Payam
authors.initials: P
authors.lastname: Tavakoli
authors.forename: Mehdi
authors.initials: M
authors.lastname: Eftekhari
authors.forename: Mohammad Akhondzadeh
authors.initials: MA
authors.lastname: Haghighi
mesh_terms: D000328:Adult; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D005260:Female; D017573:Focal Epithelial Hyperplasia / Q000473:pathology* / Q000628:therapy / Q000821:virology; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology* / Q000821:virology; D009910:Oral Hygiene; D030361:Papillomavirus Infections / Q000473:pathology* / Q000628:therapy / Q000821:virology; D012074:Remission Induction; D013997:Time Factors; D016896:Treatment Outcome