title: Transarterial therapy of hepatocellular carcinoma fed by the right renal capsular artery.
abstract: OBJECTIVE
  To evaluate the characteristics of hepatocellular carcinomas (HCCs) fed by the right renal capsular artery and to assess the tumor response and complications in patients treated with transarterial therapy via the renal capsular arteries with or without other extrahepatic arteries and/or intrahepatic arteries.
  
  
  METHODS
  Between March 2006 and May 2012, 24 lesions in 19 patients were treated by transcatheter arterial chemoembolization (23 sessions), transcatheter arterial embolization (two sessions), or transcatheter arterial infusion (one session), with HCCs fed by the right renal capsular artery with or without intrahepatic arteries and/or other collateral arteries. Other intrahepatic lesions were concurrently treated if needed.
  
  
  RESULTS
  Tumor size ranged from 10 mm to 107 mm (mean, 30.5 mm). Of the 24 tumors, 12 were located in segment VI, 10 in segment VII, one in the posterior segment, and one in the anterior segment after posterior segment resection. Severe complication occurred in four patients: liver abscess (n = 2), pleural effusion (n = 1), and duodenal ulcer (n = 1). Pleural effusion might be related to chemoembolization via the right renal capsular artery. A complete response was obtained in six sessions and a partial response in eight; 10 sessions were associated with stable disease and two with progressive disease.
  
  
  CONCLUSIONS
  Precise renal capsular artery knowledge would facilitate successful and safe transarterial therapy for HCCs fed by the renal capsular arteries.
authors.affiliation: Department of Diagnostic Radiology, Hiroshima University, Hiroshima, Japan. Electronic address: masaishi@hiroshima-u.ac.jp.
authors.forename: Masaki
authors.initials: M
authors.lastname: Ishikawa
authors.affiliation: Department of Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Takuji
authors.initials: T
authors.lastname: Yamagami
authors.affiliation: Department of Radiology, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kakizawa
authors.affiliation: Department of Radiology, Hiroshima City Hospital, Hiroshima, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Hieda
authors.affiliation: Department of Radiology, Natural Hospital Organization, Kure Medical Center, Kure, Japan.
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Toyota
authors.affiliation: Department of Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Wataru
authors.initials: W
authors.lastname: Fukumoto
authors.affiliation: Department of Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Kajiwara
authors.affiliation: Department of Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Rika
authors.initials: R
authors.lastname: Yoshimatsu
authors.affiliation: Department of Gastroenterology and Metabolism, Hiroshima University, Hiroshima, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Aikata
authors.affiliation: Department of Gastroenterology and Metabolism, Hiroshima University, Hiroshima, Japan.
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Chayama
authors.affiliation: Department of Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Awai
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000009:adverse effects* / Q000379:methods*; D005260:Female; D006801:Humans; D007269:Injections, Intra-Arterial; D008113:Liver Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D010996:Pleural Effusion / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D015641:Radiography, Interventional / Q000379:methods; D012077:Renal Artery; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents