title: [Prognostic analysis of patients with synchronous liver metastasis from gastric cancer following simultaneous gastric and liver resection].
abstract: OBJECTIVE
  To investigate the surgical results of hepatic resection for solitary metastasis form gastric cancer.
  
  
  METHODS
  Clinical data of 53 patients who underwent simultaneous curative gastric and liver resection in our hospital from January 1998 to December 2012 were analyzed retrospectively. Univariate and multivariate analyses were performed to examine independent factors for survival.
  
  
  RESULTS
  In 53 patients, the accumulated 5-year survival rate after hepatic resection was 11.3%, 14.7% for solitary metastasis and 0 for multiple metastases. The statistically significant prognostic factors affecting 5-year survival rates were found to be serosal invasion (P=0.000), lymph node metastasis (P=0.000), the degree of radical resection (P=0.044), number of hepatic metastases (P=0.000), liver metastasis size (P=0.031). Multivariate Cox regression analysis showed that the serosal invasion (RR:3.355, P=0.012) and number of hepatic metastasis (RR:7.664, P=0.000) were independent prognostic factors in patients with liver metastasis from gastric cancer.
  
  
  CONCLUSIONS
  The prognosis of solitary metastasis from gastric cancer without serosal invasion can be improved through active radical resection based on suitable indications.
authors.affiliation: Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, China. g.Shuxian@aliyun.com.
authors.forename: Liang
authors.initials: L
authors.lastname: Cao
authors.forename: Xiang
authors.initials: X
authors.lastname: Hu
mesh_terms: D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery; D008207:Lymphatic Metastasis; D015999:Multivariate Analysis; D011379:Prognosis; D012044:Regression Analysis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery; D015996:Survival Rate