title: Ectopic prolactin-producing pituitary adenoma in a benign ovarian cystic teratoma.
abstract: We report the presence of pituitary tissue in a benign ovarian cystic teratoma removed surgically from a 43-year-old woman. The pituitary consisted of non-tumorous neurohypophysis and adenohypophysis containing mainly prolactin (PRL)-immunopositive cells (80 % of cells) and a small PRL-producing adenoma. The ultrastructure of the tumor cells differed significantly from PRL cells in the non-tumorous and adenomatous intrasellar pituitary. It appears that cells differing in ultrastructure from intrasellar pituitary PRL cells can also produce PRL.
authors.affiliation: Department of Laboratory Medicine, Division of Pathology, St. Michael's Hospital, 30 Bond Street, Toronto, ON, Canada, M5B 1W8, albazzazs@smh.ca.
authors.forename: Saba
authors.initials: S
authors.lastname: Al-Bazzaz
authors.forename: Jason
authors.initials: J
authors.lastname: Karamchandani
authors.forename: Eva
authors.initials: E
authors.lastname: Mocarski
authors.forename: Eva
authors.initials: E
authors.lastname: Horvath
authors.forename: Fabio
authors.initials: F
authors.lastname: Rotondo
authors.forename: Kalman
authors.initials: K
authors.lastname: Kovacs
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*; D010911:Pituitary Neoplasms / Q000473:pathology*; D015175:Prolactinoma / Q000473:pathology*; D013724:Teratoma / Q000473:pathology*