title: Coats disease in a 3-week-old boy.
abstract: Coats disease is a rare, idiopathic retinal vasculopathy that predominantly affects males in the first decade of life. We report the case of a 3-week-old boy who presented with atypical rapidly progressing disease suggestive of Coats exudative vasculopathy. The eye developed retinal fibrosis and phthisis bulbi within 4 weeks. Retinoblastoma could not be ruled out, although histopathology after enucleation revealed no retinoblastoma. To our knowledge, this is the youngest case of Coats disease to be reported in the literature. This case highlights the wide variation in the clinical presentation of Coats disease and the difficulty in differentiating it from diffuse infiltrative retinoblastoma.
authors.affiliation: Royal Aberdeen Children's Hospital, Aberdeen, United Kingdom.
authors.forename: Charles P
authors.initials: CP
authors.lastname: Lim Fat
authors.affiliation: University Hospitals Birmingham, Edgbaston, Birmingham, United Kingdom.
authors.forename: Sam Yuen Sum
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Birmingham Children's Hospital, Birmingham, United Kingdom.
authors.forename: Marie-Anne
authors.initials: MA
authors.lastname: Brundler
authors.affiliation: Royal Aberdeen Children's Hospital, Aberdeen, United Kingdom.
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Scott
authors.affiliation: Birmingham Children's Hospital, Birmingham, United Kingdom. Electronic address: manoj.parulekar@nhs.net.
authors.forename: Manoj V
authors.initials: MV
authors.lastname: Parulekar
mesh_terms: D015353:Eye Enucleation; D005355:Fibrosis; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012160:Retina / Q000473:pathology; D012163:Retinal Detachment / Q000175:diagnosis; D058456:Retinal Telangiectasis / Q000150:complications* / Q000175:diagnosis