title: Translocation Renal Cell Carcinoma t(6;11)(p21;q12) and Sickle Cell Anemia: First Report and Review of the Literature.
abstract: Translocation renal cell carcinoma (RCC) is a family of rare tumors recently identified in the pediatric and young adult population. We report the first case of a young woman from French West Indies with sickle cell anemia who developed a translocation RCC t(6;11)(p21;q12). Usually people with the sickle cell condition are known to develop renal medullary carcinoma (RMC). To our knowledge, this is the first case described in the literature of a translocation RCC associated with sickle cell disease. Here we discuss the relation between translocation RCC, RMC, and sickle cell disease.
authors.affiliation: Department of Urology, Rennes University Hospital, Rennes, France.
authors.forename: Damien
authors.initials: D
authors.lastname: Chaste
authors.affiliation: Department of Urology, Pointe à Pitre University Hospital, Guadeloupe, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Vian
authors.affiliation: Department of Urology, Rennes University Hospital, Rennes, France.
authors.forename: Gregory
authors.initials: G
authors.lastname: Verhoest
authors.affiliation: Department of Urology, Pointe à Pitre University Hospital, Guadeloupe, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Blanchet
keywords: Hemoglobin SS; Kidney cancer; Renal cell carcinoma; Sickle cell anemia; Transcription factor EB