title: Synthesis and characterization of biocompatible nanodiamond-silk hybrid material.
abstract: A new hybrid material consisting of nanodiamonds (NDs) and silk has been synthesized and investigated. NDs can contain bright fluorescence centers, important for bioprobes to image biological structures at the nanoscale and silk provides a transparent, robust matrix for these nanoparticles in-vivo or in-vitro. The ND-silk hybrid films were determined to be highly transparent in the visible to near infrared wavelength range. The NDs embedded in silk exhibited significant enhancement of emission relative to air, correlating with theoretical predictions. Furthermore, animal toxicity tests confirmed ND-silk films to be non-toxic in an in-vivo mice model.
authors.affiliation: School of Physics, University of Melbourne, Parkville, VIC 3010, Australia.
authors.forename: Asma
authors.initials: A
authors.lastname: Khalid
authors.affiliation: School of Physics, University of Sydney, Camperdown, NSW 2006, Australia.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Lodin
authors.affiliation: School of Physics, University of Sydney, Camperdown, NSW 2006, Australia.
authors.forename: Peter
authors.initials: P
authors.lastname: Domachuk
authors.affiliation: Department of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, USA.
authors.forename: Hu
authors.initials: H
authors.lastname: Tao
authors.affiliation: Department of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, USA.
authors.forename: Jodie E
authors.initials: JE
authors.lastname: Moreau
authors.affiliation: Department of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, USA.
authors.forename: David L
authors.initials: DL
authors.lastname: Kaplan
authors.affiliation: Department of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, USA ; Department of Physics, Tufts University, Medford, Massachusetts 02155, USA.
authors.forename: Fiorenzo G
authors.initials: FG
authors.lastname: Omenetto
authors.affiliation: School of Physics, University of Melbourne, Parkville, VIC 3010, Australia ; present address: Applied Physics, School of Applied Sciences, RMIT University, Melbourne 3001, Australia.
authors.forename: Brant C
authors.initials: BC
authors.lastname: Gibson
authors.affiliation: School of Physics, University of Melbourne, Parkville, VIC 3010, Australia.
authors.forename: Snjezana
authors.initials: S
authors.lastname: Tomljenovic-Hanic
keywords: (160.4236) Nanomaterials; (180.1790) Confocal microscopy; (300.2530) Fluorescence, laser-induced