title: Systematic review focusing on the excretion and protection roles of sweat in the skin.
abstract: The skin excretes substances primarily through sweat glands. Several conditions have been demonstrated to be associated with diminished sweating. However, few studies have concentrated on the metabolism and excretion of sweat. This review focuses on the relationship between temperature and the thermoregulatory efficacy of sweat, and then discusses the excretion of sweat, which includes the metabolism of water, minerals, proteins, vitamins as well as toxic substances. The potential role of sweat secretion in hormone homeostasis and the effects on the defense system of the skin are also clarified.
authors.affiliation: Department Orthopedics and Traumatology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, P.R. China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Peng
authors.forename: Xiao
authors.initials: X
authors.lastname: Cui
authors.forename: Yanhua
authors.initials: Y
authors.lastname: Liu
authors.forename: Yaoyin
authors.initials: Y
authors.lastname: Li
authors.forename: Jian
authors.initials: J
authors.lastname: Liu
authors.forename: Biao
authors.initials: B
authors.lastname: Cheng
mesh_terms: D001833:Body Temperature Regulation / Q000502:physiology; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000378:metabolism; D007155:Immunologic Factors / Q000378:metabolism; D012867:Skin / Q000378:metabolism; D013542:Sweat / Q000737:chemistry / Q000276:immunology / Q000378:metabolism*; D013545:Sweat Glands / Q000378:metabolism*; D013546:Sweating / Q000502:physiology*
chemical_list: D007071:Immunoglobulin A, Secretory; D007155:Immunologic Factors