title: Ribosome rescue, nearing the end.
abstract: In eukaryotes, Dom34 is involved in the rescue of ribosomes that stall on mRNAs during protein synthesis. Using ribosome profiling, Guydosh and Green reveal that, in addition to rescue of ribosomes stalled on truncated mRNAs, Dom34 also recycles ribosomes that are unexpectedly found in the 3' untranslated regions of many cellular mRNAs.
authors.affiliation: Gene Center, Department for Biochemistry and Center for integrated Protein Science Munich (CiPSM), University of Munich, 81377 Munich, Germany.
authors.forename: Agata L
authors.initials: AL
authors.lastname: Starosta
authors.affiliation: Gene Center, Department for Biochemistry and Center for integrated Protein Science Munich (CiPSM), University of Munich, 81377 Munich, Germany. Electronic address: wilson@lmb.uni-muenchen.de.
authors.forename: Daniel N
authors.initials: DN
authors.lastname: Wilson
mesh_terms: D020413:3' Untranslated Regions; D018797:Cell Cycle Proteins / Q000378:metabolism*; D004722:Endoribonucleases / Q000378:metabolism*; D012270:Ribosomes / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*
chemical_list: D020413:3' Untranslated Regions; D018797:Cell Cycle Proteins; D029701:Saccharomyces cerevisiae Proteins; C112808:Dom34 protein, S cerevisiae; D004722:Endoribonucleases