title: The first peripherally masked thiol dendrimers: a facile and highly efficient functionalization strategy of polyester dendrimers via one-pot xanthate deprotection/thiol-acrylate Michael addition reactions.
abstract: Introducing multiple reactive functional groups at the periphery of dendrimer materials presents considerable challenges if the functionality is able to self-react. An efficient and facile approach to introducing masked thiols at the surface of polyester dendrimers is presented. One-pot, deprotection/thiol-acrylate Michael addition from the xanthate-functional dendritic substrates (generation zero to two) has been achieved for the first time, with high efficiency demonstrated using three acrylates of varying chemistry and avoiding disulfide formation.
authors.affiliation: Department of Chemistry, University of Liverpool, Crown Street, Liverpool L69 7ZD, UK. srannard@liv.ac.uk.
authors.forename: Sam E R
authors.initials: SE
authors.lastname: Auty
authors.forename: Oliver
authors.initials: O
authors.lastname: Andrén
authors.forename: Michael
authors.initials: M
authors.lastname: Malkoch
authors.forename: Steven P
authors.initials: SP
authors.lastname: Rannard