title: [Osteoconductive behaviour of beta-tricalcium phosphate ceramics in osteoporotic, metaphyseal bone defects of the distal radius].
abstract: BACKGROUND
  Surgical treatment of osteoporotic distal radius fractures with locking plates does not completely prevent loss of reduction. Additional bone deficit stabilisation with the use of bone substitute materials is receiving increased attention. Most knowledge on the in vivo behavior of bone substitutes originates from a small number of animal models after its implantation in young, good vascularized bone.
  
  
  OBJECTIVE
  This paper investigates the osteoconductivity, resorption and biocompatibility of beta-tricalcium phosphate as a temporary bone replacement in osteoporotic type distal radius fractures.
  
  
  METHODS
  15 bone samples taken from the augmented area of the distal radius of elderly people during metal removal were examined.
  
  
  RESULTS
  The material was found to be osteoconductive, good degradable, and biocompatible. Degrading process and remodelling to woven bone seem to require more time than in available comparative bioassays.
  
  
  CONCLUSIONS
  The material is suitable for temporary replacement of lost, distal radius bone from the histological point of view.
authors.affiliation: Hand-, Plastische und Wiederherstellungschirurgie, Kantonsspital St. Gallen, St. Gallen, Schweiz.
authors.forename: J
authors.initials: J
authors.lastname: Hainich
authors.affiliation: Muskuloskelettales Forschungszentrum, Universität Zürich, Zürich, Schweiz, Zentrum für angewandte Biotechnologie und Molekularmedizin, Universität Zürich, Zürich, Schweiz.
authors.forename: B
authors.initials: B
authors.lastname: von Rechenberg
authors.affiliation: Klinik für Unfall, Hand, Plastische und Wiederherstellungschirurgie, Universitätsklinikum Würzburg, Würzburg.
authors.forename: R G
authors.initials: RG
authors.lastname: Jakubietz
authors.affiliation: Klinik für Unfall, Hand, Plastische und Wiederherstellungschirurgie, Universitätsklinikum Würzburg, Würzburg.
authors.forename: M G
authors.initials: MG
authors.lastname: Jakubietz
authors.affiliation: Klinik für Plastische Chirurgie und Handchirurgie, Universitätsspital Zürich, Zürich, Schweiz.
authors.forename: P
authors.initials: P
authors.lastname: Giovanoli
authors.affiliation: Hand-, Plastische und Wiederherstellungschirurgie, Kantonsspital St. Gallen, St. Gallen, Schweiz.
authors.forename: J G
authors.initials: JG
authors.lastname: Grünert
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001861:Bone Regeneration / Q000502:physiology*; D016723:Bone Remodeling / Q000502:physiology; D018786:Bone Substitutes; D002130:Calcium Phosphates / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D005593:Fracture Fixation, Internal / Q000379:methods*; D017102:Fracture Healing / Q000502:physiology; D006801:Humans; D008297:Male; D008422:Materials Testing; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D058866:Osteoporotic Fractures / Q000473:pathology / Q000601:surgery*; D011884:Radius / Q000473:pathology / Q000601:surgery; D011885:Radius Fractures / Q000473:pathology / Q000601:surgery*; D013557:Switzerland; D014954:Wrist Injuries / Q000473:pathology / Q000601:surgery*
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate