title: Activity directed investigation on anti-inflammatory fractions and compounds from flowers of Trollius chinensis.
abstract: The flower of Trollius chinensis Bunge is used as an anti-inflammatory drug to treat upper respiratory tract infection, pharyngitis, tonsillitis, and bronchitis. In order to identify the active components, the activity-screen directed compound isolation was carried out, leading to the identification of the major active fraction and 4 compounds thereof. As a result, flavonoids and phenolics were demonstrated to be the major anti-inflammatory components.
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China.
authors.forename: Rufeng
authors.initials: R
authors.lastname: Wang
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China.
authors.forename: Xiuwen
authors.initials: X
authors.lastname: Wu
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China.
authors.forename: Lijia
authors.initials: L
authors.lastname: Liu
authors.affiliation: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR Chin.
authors.forename: Yannan
authors.initials: Y
authors.lastname: An
mesh_terms: D019342:Acetic Acid; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal; D002199:Capillary Permeability / Q000187:drug effects; D004365:Drugs, Chinese Herbal; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control; D005419:Flavonoids / Q000032:analysis / Q000494:pharmacology; D035264:Flowers / Q000737:chemistry*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D010636:Phenols / Q000032:analysis / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D029626:Ranunculaceae / Q000737:chemistry*; D014992:Xylenes
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D014992:Xylenes; D019342:Acetic Acid