title: Lipid membranes as solvents for carbon nanoparticles.
abstract: Fullerene is scarcely soluble in most solvents, including alkanes. Yet, it has been shown that C60 dissolves in lipid bilayers, whose interior is chemically identical to alkanes. Here, we use molecular simulations to explain why lipid bilayers are better than alkanes at dissolving fullerene clusters. Fullerene aggregation is driven by entropy, but enthalpic contributions determine the difference between alkanes and bilayers. Surprisingly, confinement and chain alignment in the bilayer do not affect fullerene aggregation, while solvent density and the perturbation of solvent-solvent interactions are key factors.
authors.affiliation: INSERM, UMR-S665, Paris F-75015, France and University Paris Diderot, Sorbonne Paris Cité, UMR-S665, Paris F-75013, France and INTS, Paris F-75015, France.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Barnoud
authors.affiliation: INSERM, UMR-S665, Paris F-75015, France and University Paris Diderot, Sorbonne Paris Cité, UMR-S665, Paris F-75013, France and INTS, Paris F-75015, France.
authors.forename: Giulia
authors.initials: G
authors.lastname: Rossi
authors.affiliation: INSERM, UMR-S665, Paris F-75015, France and University Paris Diderot, Sorbonne Paris Cité, UMR-S665, Paris F-75013, France and INTS, Paris F-75015, France.
authors.forename: Luca
authors.initials: L
authors.lastname: Monticelli
mesh_terms: D000473:Alkanes / Q000737:chemistry; D037741:Fullerenes / Q000737:chemistry; D008051:Lipid Bilayers / Q000737:chemistry*; D008563:Membrane Lipids / Q000737:chemistry*; D008956:Models, Chemical; D008958:Models, Molecular; D036103:Nanotechnology / Q000379:methods; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010713:Phosphatidylcholines / Q000737:chemistry; D012995:Solubility; D013816:Thermodynamics
chemical_list: D000473:Alkanes; D037741:Fullerenes; D008051:Lipid Bilayers; D008563:Membrane Lipids; D037742:Nanotubes, Carbon; D010713:Phosphatidylcholines; C069837:fullerene C60; C028694:1-palmitoyl-2-oleoylphosphatidylcholine