title: Mediastinal sarcoid-like reaction after colon adenocarcinoma resection.
abstract: We report a rare case of mediastinal sarcoid-like reaction presenting 5 years after colon adenocarcinoma resection. The lack of clinical and biochemical features suggestive of sarcoidosis and the high (18)F-fluorodeoxyglucose uptake in mediastinal adenopathy, not seen previously, led us to suspect cancer recurrence. Pathological diagnosis obtained with a thoracoscopic biopsy confirmed sarcoidosis. Mediastinal adenopathies need to be confirmed pathologically to avoid potential interpretative pitfalls leading to toxic overtreatment.
authors.affiliation: Thoracic Surgery Unit, Second University of Naples, Naples, Italy.
authors.forename: Alfonso
authors.initials: A
authors.lastname: Fiorelli
authors.affiliation: Department of Pathology, Second University of Naples, Naples, Italy.
authors.forename: Marina
authors.initials: M
authors.lastname: Accardo
authors.affiliation: Department of Onclology, Second University of Naples, Naples, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Orditura
authors.affiliation: Thoracic Surgery Unit, Second University of Naples, Naples, Italy mario.santini@unina2.it.
authors.forename: Mario
authors.initials: M
authors.lastname: Santini
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000368:Aged; D001706:Biopsy; D003082:Colectomy / Q000009:adverse effects*; D003110:Colonic Neoplasms / Q000473:pathology / Q000601:surgery*; D003937:Diagnosis, Differential; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008477:Mediastinal Diseases / Q000175:diagnosis / Q000209:etiology*; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D019275:Radiopharmaceuticals; D012507:Sarcoidosis / Q000175:diagnosis / Q000209:etiology*; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Chemotherapy; Fluorodeoxyglucose F18; Lymph nodes; Positron-emission tomography; Sarcoidosis; Tomography; X-ray computed; adjuvant