title: [Pediatric lung transplantation in Broussais-HEGP: a 23-year experience (1990-2013)].
abstract: BACKGROUND
  Pediatric lung transplantations (LTx) remains a small part of LTx performed worldwide. The majority of these Tx concerns young adolescents, transplantations in infants being anecdotic. We conducted a retrospective study of LTx in children and adolescents in one center in Paris from the beginning of the 90's to 2013.
  
  
  METHODS
  Data from Broussais then HEGP were collected retrospectively from 1990 to 2013: 380 LTx were reported in 368 patients including 111 LTx performed among children from 5 to 18 years of age (30%).
  
  
  RESULTS
  One hundred and eleven patients received 121 LTx: 86 bilateral LTx, 13 combined lung-liver, 3 monopulmonary, 5 heart-lung and 4 combined heart-lung-liver Tx. Eighty-eight percent of the patients had cystic fibrosis. Median age was 14 years, weight 34 kg and height 144 cm. Median age of donors was 27 years, weight 60 kg and height 167 cm. Conditional survival for children was not different than adults: 72% at one year, 42% at 5 years, 37% at 10 years and 26% at 15 years. There was not overall early mortality after transplantation. Era graft survival was significantly higher after year 2000 (53% at 5 years vs 32% P=0.03).
  
  
  CONCLUSIONS
  Lung transplantation among children under 18 years have similar outcome to those of adult patients.
authors.affiliation: Service de chirurgie cardiaque, hôpital européen Georges-Pompidou (HEGP), 20, rue Leblanc, 75015 Paris, France. Electronic address: vboussaud@egp.aphp.fr.
authors.forename: V
authors.initials: V
authors.lastname: Boussaud
authors.affiliation: Service d'anesthésie-réanimation, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Amrein
authors.affiliation: Service d'anesthésie-réanimation, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Guillemain
authors.affiliation: Service de chirurgie cardiaque, hôpital européen Georges-Pompidou (HEGP), 20, rue Leblanc, 75015 Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Achouh
authors.affiliation: Service de chirurgie cardiaque, hôpital européen Georges-Pompidou (HEGP), 20, rue Leblanc, 75015 Paris, France.
authors.forename: J-N
authors.initials: JN
authors.lastname: Fabiani
authors.affiliation: Service de chirurgie thoracique, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Le Pimpec Barthes
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006761:Hospitals; D006801:Humans; D016040:Lung Transplantation / Q000706:statistics & numerical data*; D008297:Male; D010297:Paris; D012189:Retrospective Studies; D013997:Time Factors
keywords: Cystic fibrosis; Lung transplantation; Mucoviscidose; Pediatrics; Pédiatrie; Transplantation pulmonaire