title: Short communication: effects of systemic treatment with penethamate hydriodide on udder health and milk yields in dry primiparous Mediterranean buffaloes (Bubalus bubalis).
abstract: The effects of penethamate hydriodide (Mamyzin, Boehringer Ingelheim, Ingelheim, Germany) on udder health and milk yields were evaluated in primiparous Mediterranean buffaloes (Bubalus bubalis). An intramuscular administration of 10 million international units was performed in 20 buffaloes at 7 d precalving (treatment group; TG), and 20 animals were enrolled as the control group (CG). Evening milk samplings were performed at 10, 30, and 60 d in milk (DIM). Somatic cell count (SCC) values were evaluated on composite milk samples, whereas bacteriological culture and California Mastitis Test were performed on quarter milk. Daily milk yields were recorded after all milkings. After 60 DIM, composite milk samples from each animal were collected for monthly SCC and bacteriological culture until drying off. Statistically significant differences were found between the prevalence of mastitic quarters in the 2 groups at 10 and 30 DIM, and between the incidence of mastitic animals during the examined period (TG: 4/20, 20% vs. CG: 10/20, 50%). Even though lower and higher values of SCC and milk yields were found in TG during each sampling, statistically significant differences were only found at 30 (SCC) and 60 DIM (milk yields). In our study, the antibiotic administration precalving showed good bactericidal activity against the most common udder-specific pathogens that cause mastitis in primiparous Mediterranean buffaloes, and greater efficacy was observed at 10 and 30 DIM compared with 60 DIM. Given the significant decrease in SCC and increase in yields achieved, use of this antibiotic could be economically beneficial in buffalo breeding.
authors.affiliation: Department of Veterinary Medicine and Animal Production, University of Napoli "Federico II," Via Delpino 1, 80137 Napoli, Italy. Electronic address: jacopo.guccione@unina.it.
authors.forename: J
authors.initials: J
authors.lastname: Guccione
authors.affiliation: Istituto Zooprofilattico del Mezzogiorno, Via A. Jervolino 19, 81100 Tuoro, Caserta District, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Pesce
authors.affiliation: Veterinary practitioner, 81100 Caserta, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Pascale
authors.affiliation: Boehringer Ingelheim Italia, Via Lorenzini 8, 20139 Milano, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Tommasini
authors.affiliation: Istituto Zooprofilattico del Mezzogiorno, Via A. Jervolino 19, 81100 Tuoro, Caserta District, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Garofalo
authors.affiliation: Department of Health Science, University of Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Di Loria
authors.affiliation: Department of Veterinary Medicine and Animal Production, University of Napoli "Federico II," Via Delpino 1, 80137 Napoli, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Cortese
authors.affiliation: Istituto Zooprofilattico del Mezzogiorno, Via A. Jervolino 19, 81100 Tuoro, Caserta District, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Salzano
authors.affiliation: Department of Veterinary Medicine and Animal Production, University of Napoli "Federico II," Via Delpino 1, 80137 Napoli, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Ciaramella
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002020:Buffaloes; D003612:Dairying / Q000191:economics; D005260:Female; D007273:Injections, Intramuscular / Q000662:veterinary; D007558:Italy; D007774:Lactation; D008321:Mammary Glands, Animal / Q000502:physiology; D008413:Mastitis / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*; D008892:Milk / Q000737:chemistry / Q000378:metabolism; D010298:Parity; D010400:Penicillin G / Q000031:analogs & derivatives* / Q000494:pharmacology; D011247:Pregnancy
chemical_list: D000900:Anti-Bacterial Agents; C008780:penethamate hydroiodide; D010400:Penicillin G
keywords: Mediterranean buffalo; antibiotics; mastitis; penethamate hydriodide