title: Chemical pleurodesis using a Viscum album extract in infants with congenital chylothorax.
abstract: Congenital chylothorax is a rare condition, but it is the most common cause of pleural effusion in neonates and infants. Here, we report on the first trials of the intrapleural instillation of an extract of Viscum album (European mistletoe) (Abnobaviscum Q®) in two infants with congenital chylothorax that was refractory to standard conservative management and thoracic duct ligation.
  
  
  CONCLUSIONS
  The clinical course of both children improved with no side effects related to the extract after following up the children for 2 years and 9 months, respectively. Randomized multicenter prospective studies will help determine the effectiveness of pleurodesis with a V. album extract and the occurrence of long-term side effects with this agent.
authors.affiliation: Department of Pediatrics, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, South Korea.
authors.forename: Hwa Jin
authors.initials: HJ
authors.lastname: Cho
authors.forename: Kook Joo
authors.initials: KJ
authors.lastname: Na
authors.forename: Do Wan
authors.initials: DW
authors.lastname: Kim
authors.forename: Young Earl
authors.initials: YE
authors.lastname: Choi
authors.forename: Jae Sook
authors.initials: JS
authors.lastname: Ma
authors.forename: In Seok
authors.initials: IS
authors.lastname: Jeong
mesh_terms: D002916:Chylothorax / Q000151:congenital* / Q000000981:diagnostic imaging / Q000188:drug therapy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008517:Phytotherapy / Q000379:methods*; D010936:Plant Extracts / Q000008:administration & dosage*; D010994:Pleura / Q000000981:diagnostic imaging / Q000187:drug effects; D018700:Pleurodesis / Q000379:methods*; D011859:Radiography; D028182:Viscum album / Q000737:chemistry*
chemical_list: D010936:Plant Extracts; C508047:abnoba viscum