title: WHO recommendations for the viruses used in the 2013-2014 Northern Hemisphere influenza vaccine: Epidemiology, antigenic and genetic characteristics of influenza A(H1N1)pdm09, A(H3N2) and B influenza viruses collected from October 2012 to January 2013.
abstract: In February the World Health Organisation (WHO) recommends influenza viruses to be included in influenza vaccines for the forthcoming winter in the Northern Hemisphere. These recommendations are based on data collected by National Influenza Centres (NICs) through the WHO Global Influenza Surveillance and Response System (GISRS) and a more detailed analysis of representative and potential antigenically variant influenza viruses from the WHO Collaborating Centres for Influenza (WHO CCs) and Essential Regulatory Laboratories (ERLs). This article provides a detailed summary of the antigenic and genetic properties of viruses and additional background data used by WHO experts during development of the recommendations of the 2013-2014 Northern Hemisphere influenza vaccine composition.
authors.affiliation: WHO Collaborating Centre for Reference and Research on Influenza, Victorian Infectious Diseases Reference Laboratory (VIDRL), Melbourne, Australia. Electronic address: Ian.Barr@influenzacentre.org.
authors.forename: Ian G
authors.initials: IG
authors.lastname: Barr
authors.affiliation: University of Cambridge, UK.
authors.forename: Colin
authors.initials: C
authors.lastname: Russell
authors.affiliation: WHO Global Influenza Programme (GIP), Geneva, Switzerland.
authors.forename: Terry G
authors.initials: TG
authors.lastname: Besselaar
authors.affiliation: WHO Collaborating Centre for Surveillance, Epidemiology and Control of Influenza, Centers for Disease Control and Prevention, Atlanta, USA.
authors.forename: Nancy J
authors.initials: NJ
authors.lastname: Cox
authors.affiliation: WHO Collaborating Centre for Reference and Research on Influenza, Medical Research Council - National Institute for Medical Research (NIMR), London, UK.
authors.forename: Rod S
authors.initials: RS
authors.lastname: Daniels
authors.affiliation: WHO Collaborating Centre for Surveillance, Epidemiology and Control of Influenza, Centers for Disease Control and Prevention, Atlanta, USA.
authors.forename: Ruben
authors.initials: R
authors.lastname: Donis
authors.affiliation: National Institute for Biological Standards and Control (NIBSC), Health Protection Agency (HPA), Potters Bar, UK.
authors.forename: Othmar G
authors.initials: OG
authors.lastname: Engelhardt
authors.affiliation: Therapeutic Goods Administration (TGA), Canberra, Australia.
authors.forename: Gary
authors.initials: G
authors.lastname: Grohmann
authors.affiliation: WHO Collaborating Centre for Reference and Research on Influenza, National Institute of Infectious Diseases (NIID), Tokyo, Japan.
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Itamura
authors.affiliation: WHO Collaborating Centre for Reference and Research on Influenza, Victorian Infectious Diseases Reference Laboratory (VIDRL), Melbourne, Australia.
authors.forename: Anne
authors.initials: A
authors.lastname: Kelso
authors.affiliation: WHO Collaborating Centre for Reference and Research on Influenza, Medical Research Council - National Institute for Medical Research (NIMR), London, UK.
authors.forename: John
authors.initials: J
authors.lastname: McCauley
authors.affiliation: WHO Collaborating Centre for Reference and Research on Influenza, National Institute of Infectious Diseases (NIID), Tokyo, Japan.
authors.forename: Takato
authors.initials: T
authors.lastname: Odagiri
authors.affiliation: St Jude Children's Research Hospital, Memphis, USA.
authors.forename: Stacey
authors.initials: S
authors.lastname: Schultz-Cherry
authors.affiliation: WHO Collaborating Center for Reference and Research on Influenza, Chinese National Influenza Center (CNIC), Beijing, PR China.
authors.forename: Yuelong
authors.initials: Y
authors.lastname: Shu
authors.affiliation: Centre for Pathogen Evolution and WHOCC for Modelling Evolution and Control of Emerging Infectious Diseases, University of Cambridge, UK and Fogarty International Centre, National Institutes of Health (NIH), USA.
authors.forename: Derek
authors.initials: D
authors.lastname: Smith
authors.affiliation: WHO Collaborating Centre for Reference and Research on Influenza, National Institute of Infectious Diseases (NIID), Tokyo, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Tashiro
authors.affiliation: WHO Collaborating Center for Reference and Research on Influenza, Chinese National Influenza Center (CNIC), Beijing, PR China.
authors.forename: Dayan
authors.initials: D
authors.lastname: Wang
authors.affiliation: St Jude Children's Research Hospital, Memphis, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Webby
authors.affiliation: WHO Collaborating Centre for Surveillance, Epidemiology and Control of Influenza, Centers for Disease Control and Prevention, Atlanta, USA.
authors.forename: Xiyan
authors.initials: X
authors.lastname: Xu
authors.affiliation: Food and Drug Administration (FDA), Center for Biologics Evaluation and Research (CBER), Bethesda, MD, USA.
authors.forename: Zhiping
authors.initials: Z
authors.lastname: Ye
authors.affiliation: WHO Global Influenza Programme (GIP), Geneva, Switzerland.
authors.forename: Wenqing
authors.initials: W
authors.lastname: Zhang
mesh_terms: D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics / Q000276:immunology; D053122:Influenza A Virus, H3N2 Subtype / Q000235:genetics / Q000276:immunology; D009981:Influenza B virus / Q000235:genetics / Q000276:immunology; D007252:Influenza Vaccines / Q000627:therapeutic use*; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control; D014944:World Health Organization
chemical_list: D007252:Influenza Vaccines
keywords: 2013–2014; Human; Influenza; Northern Hemisphere; Quadrivalent; Recommendation; Trivalent; Vaccine