title: Optical coherence tomography diagnostics for onco-urology. Review of clinical perspectives.
abstract: BACKGROUND
  Optical coherence tomography (OCT) is being investigated widely for use in urologic pathology. The current imaging of urogenital cancers cannot be perfect, thus, routine methods demands new updates or inventions of alternative radiological scope. OCT presents so-called "live" optical biopsy. The authors aim to review this modality for uro-oncological purposes.
  
  
  METHODS
  [corrected] A series of 37 publications between 1989 and 2012 was selected and cited from GoogleScholar and PubMED/MEDLINE. The urogenital tract (bladder, ureter, scrotum organs and prostate) was imaged by OCT.
  
  
  RESULTS
  The overall OCT sensitivity, specificity, accuracy, negative and positive predictive values ranged a lot on example of the urinary bladder's tumors screening. The data were 75-100%, 65-97.9%, 92%, 75%, 100%, respectively. Notwithstanding, a diagnostic importance of OCT may be comparable with urine cytology, cystoscopy, computerized tomography and magnetic resonance imaging.
  
  
  CONCLUSIONS
  OCT demonstrated its imaging potential, while till the present OCT plays role of an additional imaging. Future progress of OCT involvement in experimental and clinical once-urological diagnostics is needed under high evidence control.
authors.affiliation: The Medical Institute of Sumy State University, Faculty of Post-graduate Medical Education, Department of General, Pediatric Surgery with Oncology's Course, Glukhiv Central District Hospital, Surgical Division, Glukhiv, Ukraine.
authors.forename: Sergiy
authors.initials: S
authors.lastname: Kharchenko
authors.affiliation: Nicolaus Copernicus University, Faculty of Medicine, Department Tissue Engineering, Bydgoszcz, Poland.
authors.forename: Jan
authors.initials: J
authors.lastname: Adamowicz
authors.affiliation: Nicolaus Copernicus University, Institute of Physics, Department of Biophysics and Medical Physics, Toruń, Poland.
authors.forename: Maciej
authors.initials: M
authors.lastname: Wojtkowski
authors.affiliation: Nicolaus Copernicus University, Faculty of Medicine, Department Tissue Engineering, Bydgoszcz, Poland ; Department of Urology Nicolaus Copernicus Hospital, Toruń, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Drewa
keywords: oncology; optical coherence tomography; urology