title: Dedifferentiated chondrosarcoma: an aggressive variant of chondrosarcoma.
abstract: Dedifferentiated chondrosarcomas are a rare and aggressive subtype of chondrosarcoma with a bimorphic pattern on histopathology. Rib is a rare site of dedifferentiated chondrosarcoma. Diagnosis of this subtype preoperatively can be challenging. Treatment options for dedifferentiated chondrosarcoma are limited because they are chemoresistant, and therefore adequate surgery forms the main stay of treatment. We present our experience with a dedifferentiated chondrosarcoma of the rib, and discuss the management of this rare entity.
authors.affiliation: Department of Surgical Oncology, St. John's Medical College & Hospital, Bangalore, India.
authors.forename: Gangadhara
authors.initials: G
authors.lastname: Bharath
authors.affiliation: Department of Surgical Oncology, St. John's Medical College & Hospital, Bangalore, India rburrah@yahoo.com.
authors.forename: Rajaram
authors.initials: R
authors.lastname: Burrah
authors.affiliation: Department of Surgical Oncology, St. John's Medical College & Hospital, Bangalore, India.
authors.forename: Kuppuswamy
authors.initials: K
authors.lastname: Shivakumar
authors.affiliation: Department of Surgical Oncology, St. John's Medical College & Hospital, Bangalore, India.
authors.forename: Suraj
authors.initials: S
authors.lastname: Manjunath
authors.affiliation: Department of Pathology, St. John's Medical College & Hospital, Bangalore, India.
authors.forename: Rao
authors.initials: R
authors.lastname: Bhanumathi
mesh_terms: D001706:Biopsy; D001859:Bone Neoplasms / Q000145:classification / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D054337:Cell Dedifferentiation; D002813:Chondrosarcoma / Q000145:classification / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010027:Osteotomy; D011237:Predictive Value of Tests; D019651:Plastic Surgery Procedures; D012272:Ribs / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Bone neoplasms; chondrosarcoma; ribs