title: Numerical analysis of 3D blood flow and common carotid artery hemodynamics in the carotid artery bifurcation with stenosis.
abstract: The results for blood flow in the carotid artery bifurcation on the basis of numerical simulation of Navier-Stokes equations are presented in this study. Four cases of carotid bifurcation are considered: common carotid artery (CCA) bifurcation without stenoses and cases with one, two and three stenoses are also presented. The results are obtained by performing numerical simulations considering one pulse wave period based on the finite volume discretization of Navier-Stokes equations. The structures of the flow around the bifurcation are obtained and the deformation of the pulse wave from common carotid artery (CCA) to the internal carotid artery (ICA) and external carotid artery (ECA) is traced. The axial velocity and wall shear stress (WSS) distribution and contours are presented considering the characteristic time points. The results of the WSS distribution around the bifurcation allow a prediction of the probable sites of stenosis growth.
authors.affiliation: Department of Biomechanics, Institute of Mechanics, Bulgarian Academy of Sciences, Bulgaria.
authors.forename: N
authors.initials: N
authors.lastname: Antonova
authors.affiliation: School of Civil Engineering, Tianjin University, Tianjin, China.
authors.forename: X
authors.initials: X
authors.lastname: Dong
authors.affiliation: Department of Biomechanics, Institute of Mechanics, Bulgarian Academy of Sciences, Bulgaria.
authors.forename: P
authors.initials: P
authors.lastname: Tosheva
authors.affiliation: Department of Engineering, University College London, London, UK.
authors.forename: E
authors.initials: E
authors.lastname: Kaliviotis
authors.affiliation: Department of Neurology, University Hospital of Neurology and Psychiatry "St. Naum", Medical University, Sofia, Bulgaria.
authors.forename: I
authors.initials: I
authors.lastname: Velcheva
mesh_terms: D001783:Blood Flow Velocity; D017536:Carotid Artery, Common / Q000503:physiopathology*; D016893:Carotid Stenosis / Q000000981:diagnostic imaging; D006439:Hemodynamics / Q000502:physiology*; D018056:Hemorheology; D021621:Imaging, Three-Dimensional; D008955:Models, Cardiovascular; D009716:Numerical Analysis, Computer-Assisted; D011859:Radiography; D012039:Regional Blood Flow / Q000502:physiology*; D013314:Stress, Mechanical
keywords: 3D blood flow numerical analysis; carotid bifurcation; stenosis; wall shear stress; whole blood viscosity