title: Isolated nasal tip metastasis from esophageal squamous cell carcinoma.
abstract: Cutaneous metastatic tumors to the nasal tip are very rare. A 74-year-old woman presented with progressive dysphagia for 4 months and a painless red violaceous nodule in the nasal tip for the last 6 weeks. Gastroendoscopy showed midesophageal wall thickening, which corresponded to esophageal squamous cell carcinoma confirmed by endoscopic biopsy. F-FDG PET/CT showed intense FDG uptake of the esophageal carcinoma (SUVmax, 19.0) and the nasal tip nodule (SUVmax, 29.1). The patient underwent biopsy of the nasal tip nodule. Nasal tip metastasis from the esophageal squamous cell carcinoma was confirmed by pathologic examination.
authors.affiliation: From the Departments of *Nuclear Medicine, †Pathology, and ‡Otorhinolaryngology, Changhai Hospital, Second Military Medical University, Shanghai, China.
authors.forename: Aisheng
authors.initials: A
authors.lastname: Dong
authors.forename: Changjing
authors.initials: C
authors.lastname: Zuo
authors.forename: Yang
authors.initials: Y
authors.lastname: Wang
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Zhai
authors.forename: Wu
authors.initials: W
authors.lastname: Wen
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D000077277:Esophageal Squamous Cell Carcinoma; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D064847:Multimodal Imaging; D009669:Nose Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012878:Skin Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18