title: [Correlation between adipocytokines levels and metabolic syndrome in type 2 diabetes mellitus].
abstract: OBJECTIVE
  To study the correlation between adipocytokines levels and metabolic syndrome (MS) in patients with newly diagnosed type 2 diabetes mellitus (T2DM).
  
  
  METHODS
  Sixty-eight patients with newly diagnosed T2DM, including 51 cases with MS and 17 without MS, were examined for blood pressure (BP), fasting blood glucose (FBG), fasting insulin (FINS), insulin resistance index (IRI), waist to hip ratio (W/H), body mass index (BMI), and serum adipocytokine levels (IL-6, vaspin, and adiponectin).
  
  
  RESULTS
  The diabetic patients with MS had higher BMI, HbA1c, FBG, FINS, IRI, TG, TC, and SBP than those without MS. Serum IL-6 level was higher but adiponectin level was lower in patients with MS than in those without MS. There was no significant difference in vaspin level between the two groups. Adiponectin level was positively correlated with TG (r=-0.30, P=0.02) and inversely with BMI (r=-0.47, P=0.39) and HOMA-IR (r=-0.30, P=0.03); vaspin level was positively correlated with HOMA-IR (r=0.347, P=0.02) and inversely with HDL-L (r=-0.45, P=0.01); IL-6 level was positively correlated with LDL-L (r=0.18, P=0.25) and inversely with HDL-L (r=-0.45, P=0.01).
  
  
  CONCLUSIONS
  Adiponectin and IL-6 levels are closely related to MS, but the relationship between vaspin and MS needs further investigation.
authors.affiliation: Department of Endocrinology, Zhujiang Hosipital, Southern Medical University, Guangzhou 510282, China.E-mail: yixueyingyang@126.com.
authors.forename: Ting
authors.initials: T
authors.lastname: Yan
authors.forename: Lingling
authors.initials: L
authors.lastname: Li
authors.forename: Huaiming
authors.initials: H
authors.lastname: Wang
authors.forename: Jiao
authors.initials: J
authors.lastname: Wang
authors.forename: Dehong
authors.initials: D
authors.lastname: Cai
mesh_terms: D054392:Adipokines / Q000097:blood*; D052242:Adiponectin / Q000097:blood; D000273:Adipose Tissue / Q000378:metabolism; D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications*; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D015843:Serpins / Q000097:blood
chemical_list: D054392:Adipokines; D052242:Adiponectin; C508600:IL6 protein, human; D015850:Interleukin-6; C507339:SERPINA12 protein, human; D015843:Serpins