title: Acquired ichthyosis triggered by an osseous hemangiopericytoma: a case report and review of the literature.
abstract: Ichthyoses are a heterogeneous group of cutaneous keratinization disorders that can be congenital or acquired. Apart from neoplastic disorders, the acquired form of ichthyosis (AI) has been associated with a variety of diseases including infections, autoimmune/inflammatory and endocrine/metabolic diseases as well as nutritional conditions, medications and others. However, malignancy accounts for half of the reported cases, most commonly including lymphoproliferative disorders. We present a case of AI as a paraneoplastic skin manifestation of a primary, osseous hemangiopericytoma (HP) accompanied by multiple liver metastases. We also review the literature and discuss the necessity of investigating underlying diseases, especially malignancy, when adult-onset ichthyosis arises.
authors.affiliation: 2nd Department of Dermatology and Venereology, Aristotle University School of Medicine, Thessaloniki, Greece.
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Patsatsi
authors.affiliation: 2nd Department of Dermatology and Venereology, Aristotle University School of Medicine, Thessaloniki, Greece.
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Kyriakou
authors.affiliation: Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece.
authors.forename: Vasilios
authors.initials: V
authors.lastname: Karavasilis
authors.affiliation: 2nd Department of Dermatology and Venereology, Aristotle University School of Medicine, Thessaloniki, Greece.
authors.forename: Fragkiski
authors.initials: F
authors.lastname: Tsatsou
authors.affiliation: Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece.
authors.forename: Georgios
authors.initials: G
authors.lastname: Lazaridis
authors.affiliation: 2nd Department of Dermatology and Venereology, Aristotle University School of Medicine, Thessaloniki, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Kalabalikis
authors.affiliation: 2nd Department of Dermatology and Venereology, Aristotle University School of Medicine, Thessaloniki, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Sotiriadis
keywords: Acquired ichthyosis; Hemangiopericytoma; Paraneoplastic skin disease