title: Cryptococcal infection in non-HIV immunosuppressed patients - Three case reports in a nephrology setting.
abstract: Cryptococcal infection has been increasing among immunosuppressed population. We report three cases of Cryptococcus neoformans infection in immunosuppressed patients - two renal transplanted and one with lupus nephritis. Early infection (<3months) was diagnosed in two - an allograft Cryptococcus infection and a central nervous system involvement. The third, a 10-year transplant vintage patient, presented with cryptococcal meningitis. Amphotericin B provided good clinical outcomes. We outline the importance of suspicion for cryptococcal infection in immunosuppressed patients.
authors.affiliation: Nephrology Department - Oporto Hospital Centre, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
authors.forename: Pedro
authors.initials: P
authors.lastname: Ventura Aguiar
authors.affiliation: Microbiology Department - Oporto Hospital Centre, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
authors.forename: Virgínia
authors.initials: V
authors.lastname: Lopes
authors.affiliation: Nephrology Department - Oporto Hospital Centre, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
authors.forename: La Salete
authors.initials: LS
authors.lastname: Martins
authors.affiliation: Nephrology Department - Oporto Hospital Centre, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
authors.forename: Josefina
authors.initials: J
authors.lastname: Santos
authors.affiliation: Nephrology Department - Oporto Hospital Centre, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
authors.forename: Manuela
authors.initials: M
authors.lastname: Almeida
authors.affiliation: Nephrology Department - Oporto Hospital Centre, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
authors.forename: Sofia
authors.initials: S
authors.lastname: Pedroso
authors.affiliation: Nephrology Department - Oporto Hospital Centre, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
authors.forename: Leonídio
authors.initials: L
authors.lastname: Dias
authors.affiliation: Nephrology Department - Oporto Hospital Centre, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
authors.forename: António
authors.initials: A
authors.lastname: Castro Henriques
authors.affiliation: Microbiology Department - Oporto Hospital Centre, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
authors.forename: Helena
authors.initials: H
authors.lastname: Ramos
authors.affiliation: Nephrology Department - Oporto Hospital Centre, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
authors.forename: António
authors.initials: A
authors.lastname: Cabrita
keywords: Cryptococcosis; Immunosuppression; Lupus; Meningoencephalitis; Transplant