title: Comparing suppository mold variability which can lead to dosage errors for suppositories prepared with the same or different molds.
abstract: Suppository molds must be properly calibrated to ensure accurate dosing. There are often slight differences between molds and even in the cavities within a mold. A method is presented for the calibration of standard aluminum 6-, 12-, 50-, or 100-well suppository molds. Ten different molds were tested using water for volume calibration, and cocoa butter for standardization involving establishing the density factor. This method is shown to be straightforward and appropriate for calibrating suppository molds.
authors.affiliation: University of Toledo, College of Pharmacy and Pharmaceutical Sciences, Toledo, OH 43614, USA. kenneth.alexander@utoledo.edu
authors.forename: Kenneth S
authors.initials: KS
authors.lastname: Alexander
authors.affiliation: University of Toledo, College of Pharmacy and Pharmaceutical Sciences, Toledo, OH 43614, USA.
authors.forename: Gabriella
authors.initials: G
authors.lastname: Baki
authors.affiliation: University of Toledo, College of Pharmacy and Pharmaceutical Sciences, Toledo, OH 43614, USA.
authors.forename: Christine
authors.initials: C
authors.lastname: Hart
authors.affiliation: University of Toledo, College of Pharmacy and Pharmaceutical Sciences, Toledo, OH 43614, USA.
authors.forename: Courtney
authors.initials: C
authors.lastname: Hejduk
authors.affiliation: University of Toledo, College of Pharmacy and Pharmaceutical Sciences, Toledo, OH 43614, USA.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Chillas
mesh_terms: D002138:Calibration; D013488:Suppositories; D013678:Technology, Pharmaceutical
chemical_list: D013488:Suppositories