title: Spatially marking and quantitatively counting membrane immunoglobulin M in live cells via Ag cluster-aptamer probes.
abstract: A probe composed of an aptamer and a silver cluster, where the aptamer targets mIgM of live cells and the silver cluster provides fluorescent imaging and mass quantification of mIgM of live cells, is presented. This new probe simultaneously provides accurate spatial and mass information of mIgM in live cells.
authors.affiliation: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, P. R. China. gaoxy@ihep.ac.cn.
authors.forename: Ru
authors.initials: R
authors.lastname: Liu
authors.forename: Jiao
authors.initials: J
authors.lastname: Zhai
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.forename: Yaling
authors.initials: Y
authors.lastname: Wang
authors.forename: Yueteng
authors.initials: Y
authors.lastname: Wei
authors.forename: Xinglu
authors.initials: X
authors.lastname: Jiang
authors.forename: Liang
authors.initials: L
authors.lastname: Gao
authors.forename: Huarui
authors.initials: H
authors.lastname: Zhu
authors.forename: Yuliang
authors.initials: Y
authors.lastname: Zhao
authors.forename: Zhifang
authors.initials: Z
authors.lastname: Chai
authors.forename: Xueyun
authors.initials: X
authors.lastname: Gao
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques; D045744:Cell Line, Tumor; D002462:Cell Membrane; D005453:Fluorescence; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis*; D012834:Silver / Q000737:chemistry*
chemical_list: D052157:Aptamers, Nucleotide; D007075:Immunoglobulin M; D012834:Silver