title: The evaluation of carotid intima-media thickness and visceral obesity as an atherosclerosis predictor in newly-diagnosed polycystic ovary syndrome.
abstract: OBJECTIVE
  Polycystic ovary syndrome (PCOS) is a common endocrine disorder which is associated with multiple risk factors for atherosclerosis. The aim of this study was to investigate the CIMT which is used in the early diagnosis of atherosclerosis and visceral obesity by ultrasound in newly diagnosed polycystic ovary syndrome with normal body mass index.
  
  
  METHODS
  A case-control study was conducted on 25 PCOS women (18-30 years of age) and 25 controls. BMI was matched volunteer controls. Carotid intima media thickness (CIMT) and fat distribution as visceral fat thickness (VFT) with subcutaneous fat thickness (SFT) were measured by ultrasound. After, visceral fat ratio (VFR) fat ratio (VFR) was calculated using VFT divided by SFT. The variables were compared using the χ(2)-test and Student's t test.
  
  
  RESULTS
  Comparing women with PCOS to the control group showed that CIMT was similar in both groups (p=0.84). The VFT in the PCOS group was higher than the control group (p=0.048). Whereas, the SFT was higher in the control group when compared to women with PCOS (p=0.007). The VFR was significantly higher in women with PCOS when compared to the control group (1.12 ± 0.38 vs. 0.81 ± 0.34; p=0.005).
  
  
  CONCLUSIONS
  CIMT which used as early atherosclerosis predictors have not increased in newly diagnosed PCOS women. Body fat distribution was observed in visceral area in the newly diagnosed PCOS women. VFR follow up may provide benefit as a quantitative method for the assessment and follow up of visceral obesity in women with PCOS.
authors.affiliation: Departments of Radiology, Duzce University, Medicine School, Duzce- Turkey.
authors.forename: R
authors.initials: R
authors.lastname: Buyukkaya
authors.affiliation: Departments of Radiology, Duzce University, Medicine School, Duzce- Turkey.
authors.forename: F H
authors.initials: FH
authors.lastname: Besir
authors.affiliation: Departments of Radiology, Duzce University, Medicine School, Duzce- Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Yazgan
authors.affiliation: Departments of Obstetrics and Gynecology, Duzce University, Medicine School, Duzce- Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Karatas
authors.affiliation: Departments of Obstetrics and Gynecology, Duzce University, Medicine School, Duzce- Turkey.
authors.forename: S A
authors.initials: SA
authors.lastname: Kose
authors.affiliation: Departments of Endocrinology, Duzce University, Medicine School, Duzce- Turkey.
authors.forename: Y
authors.initials: Y
authors.lastname: Aydin
authors.affiliation: Departments of Radiology, Duzce University, Medicine School, Duzce- Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Erdogmus
mesh_terms: D000293:Adolescent; D000328:Adult; D050197:Atherosclerosis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D059168:Carotid Intima-Media Thickness; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D056128:Obesity, Abdominal / Q000150:complications*; D011085:Polycystic Ovary Syndrome / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D012307:Risk Factors; D055815:Young Adult