title: Silylethynyl substituents as porphyrin protecting groups for solubilization and selectivity control.
abstract: Silylethynyl substituents are proposed as protecting groups for porphyrin derivatives to enhance their solubility and enable regioselective functionalization. After usage as protecting groups, silylethynyl groups at the meso-positions can be efficiently removed upon heating with aqueous H2SO4 in the presence of a surfactant. This approach was applied to the preparation of unsymmetrically β-substituted porphyrins and porphin-porphyrin oligomers, which were inaccessible by conventional methods.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Nagoya University , Nagoya, 464-8603, Japan.
authors.forename: Kazuma
authors.initials: K
authors.lastname: Oda
authors.forename: Masanari
authors.initials: M
authors.lastname: Akita
authors.forename: Satoru
authors.initials: S
authors.lastname: Hiroto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shinokubo