title: Asymptomatic solitary cerebral metastasis from papillary carcinoma thyroid: 131I SPECT/CT for accurate staging.
abstract: Isolated asymptomatic brain metastasis in papillary carcinoma thyroid (PCT) is extremely rare. We here present such a case of a 48-year-old woman with PCT. SPECT/CT localized the 131I radiotracer concentration seen on whole-body scan in this patient to the right posterior parietal cortex, suggesting brain metastasis. Contrast-enhanced MRI and 18F-FDG PET/CT confirmed the diagnosis and the patient was taken for gamma-knife radiosurgery. 131I SPECT/CT in this case accurately restaged the patient by detecting asymptomatic isolated brain metastasis and correctly directed the management strategy.
authors.affiliation: From the *Departments of Nuclear Medicine and †Pathology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Tarun Kumar
authors.initials: TK
authors.lastname: Jain
authors.forename: Sellam
authors.initials: S
authors.lastname: Karunanithi
authors.forename: Punit
authors.initials: P
authors.lastname: Sharma
authors.forename: Maneesh Kumar
authors.initials: MK
authors.lastname: Vijay
authors.forename: Sanjana
authors.initials: S
authors.lastname: Ballal
authors.forename: Chandrasekhar
authors.initials: C
authors.lastname: Bal
mesh_terms: D058070:Asymptomatic Diseases; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D002291:Carcinoma, Papillary; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007457:Iodine Radioisotopes; D008875:Middle Aged; D064847:Multimodal Imaging; D019275:Radiopharmaceuticals; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18