title: Varenicline-induced acute dystonic reaction: a case report.
abstract: Dystonia is a syndrome characterized by sustained muscle contractions frequently causing twisting and repetitive movements or abnormal postures. Dystonic reactions may be a complication of many drugs such as antipsychotics, anti-emetics and antidepressants. This report presents a 25-year-old patient who was admitted to an emergency department with acute dystonia following the use of varenicline, a pharmacological agent used for the treatment of nicotine addiction. Dystonic reactions may be related to the dopaminergic deficiency caused by the use of varenicline. In conclusion, this report suggests that varenicline can cause dystonic reaction in at least some patients.
authors.affiliation: Department of Neurology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
authors.forename: Ali Ulvi
authors.initials: AU
authors.lastname: Uca
authors.affiliation: Department of Neurology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
authors.forename: Hasan Hüseyin
authors.initials: HH
authors.lastname: Kozak
authors.affiliation: Department of Psychiatry, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey. Electronic address: farukuguz@gmail.com.
authors.forename: Faruk
authors.initials: F
authors.lastname: Uguz
mesh_terms: D000328:Adult; D001552:Benzazepines / Q000009:adverse effects*; D004421:Dystonia / Q000139:chemically induced* / Q000188:drug therapy; D006801:Humans; D008297:Male; D018722:Nicotinic Agonists / Q000009:adverse effects*; D011810:Quinoxalines / Q000009:adverse effects*; D016540:Smoking Cessation / Q000379:methods; D000068580:Varenicline
chemical_list: D001552:Benzazepines; D018722:Nicotinic Agonists; D011810:Quinoxalines; D000068580:Varenicline
keywords: Dytonic reaction; Varenicline