title: Quality of life and health status among prostate cancer survivors and noncancer population controls.
abstract: OBJECTIVE
  To examine whether quality of life (QOL), health status, and the relationships between them varied by having a prostate cancer history. This study helps to inform the interface between aging-related health decline and the survival state among older men with prostate cancer, which is an important yet understudied public health issue.
  
  
  METHODS
  Hierarchical linear models were used to analyze the cross-sectional data from the nationally representative population-based Medical Expenditure Panel Survey. Using propensity score matching, survivors (respondents with prostate cancer history) and controls (respondents without a history of any cancer) (N = 193 pairs) were matched based on 7 sociodemographic and health-related factors. QOL was measured using the mental and physical component scores of the SF-12 (SF-36.org). Health status included comorbidities, activities of daily living (ADL), instrumental ADL, and depressed mood.
  
  
  RESULTS
  In bivariate analyses, survivors reported worse physical (42.72 vs 45.45 respectively; P = .0040) and mental QOL (51.59 vs 53.73 respectively; P = .0295) and more comorbidities (3.25 vs 2.78 respectively; P = .0139) than controls. In multivariate analyses, for both survivors and controls, better physical QOL was associated with fewer comorbidities (P <.0001), no need help with ADL (P = .0011) and IADL (P = .0162), and less depressed mood (P <.0001); better mental QOL was associated with no need help with IADL (P = .0005) and less depressed mood (P <.0001).
  
  
  CONCLUSIONS
  QOL of older men is affected by physical, functional, and psychological factors rather than prostate cancer history. Clinicians need to attend to aging-related health issues when providing care for prostate cancer survivors to improve QOL.
authors.affiliation: Department of Adult and Geriatric Health, School of Nursing, University of North Carolina (UNC), Chapel Hill, NC; Lineberger Comprehensive Cancer Center, UNC, Chapel Hill, NC. Electronic address: lsong@unc.edu.
authors.forename: Lixin
authors.initials: L
authors.lastname: Song
authors.affiliation: Asia Research Institute, National University of Singapore, Singapore.
authors.forename: Yingchun
authors.initials: Y
authors.lastname: Ji
authors.affiliation: Department of Adult and Geriatric Health, School of Nursing, University of North Carolina (UNC), Chapel Hill, NC; Division of Urologic Surgery, School of Medicine, UNC, Chapel Hill, NC.
authors.forename: Mathew E
authors.initials: ME
authors.lastname: Nielsen
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D016022:Case-Control Studies; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003863:Depression / Q000523:psychology; D006304:Health Status; D006801:Humans; D007182:Income; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology*; D014481:United States