title: Complete 1H NMR assignments of pyrrolizidine alkaloids and a new eudesmanoid from Senecio polypodioides.
abstract: Chemical investigation of the aerial parts of Senecio polypodioides lead to the isolation of the new eudesmanoid 1β-angeloyloxyeudesm-7-ene-4β,9α-diol (1) and the known dirhamnosyl flavonoid lespidin (3), while from roots, the known 7β-angeloyloxy-1-methylene-8α-pyrrolizidine (5) and sarracine N-oxide (6), as well as the new neosarracine N-oxide (8), were obtained. The structure of 1 and 8 was elucidated by spectral means. Complete assignments of the (1)H NMR data for 5, 6, sarracine (7), and 8 were made using one-dimensional and two-dimensional NMR experiments and by application of the iterative full spin analysis of the PERCH NMR software.
authors.affiliation: Departamento de Química Orgánica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Prolongación de Carpio y Plan de Ayala, Col. Santo Tomás, México, 11340, Mexico.
authors.forename: Claudia
authors.initials: C
authors.lastname: Villanueva-Cañongo
authors.forename: Nury
authors.initials: N
authors.lastname: Pérez-Hernández
authors.forename: Beatriz
authors.initials: B
authors.lastname: Hernández-Carlos
authors.forename: Ernestina
authors.initials: E
authors.lastname: Cedillo-Portugal
authors.forename: Pedro
authors.initials: P
authors.lastname: Joseph-Nathan
authors.forename: Eleuterio
authors.initials: E
authors.lastname: Burgueño-Tapia
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D011522:Protons; D011763:Pyrrolizidine Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D012015:Reference Standards; D012674:Senecio / Q000737:chemistry*; D045787:Sesquiterpenes, Eudesmane / Q000737:chemistry / Q000302:isolation & purification*; D012984:Software
chemical_list: D011522:Protons; D011763:Pyrrolizidine Alkaloids; D045787:Sesquiterpenes, Eudesmane
keywords: 1β-angeloyloxyeudesm-7-ene-4β,9α-diol; 7β-angeloyloxy-1-methylene-8α-pyrrolizidine; Senecio polypodioides; iterative 1H NMR analysis; neosarracine N-oxide; sarracine; sarracine N-oxide