title: Bullous pemphigoid induced by hydrochlorothiazide therapy.
abstract: The most common subepidermal blistering disorder, bullous pemphigoid (BP) typically occurs in the elderly without any obvious inciting event. 1 Anti-basement membrane zone antibodies are typically detected on direct and indirect immunofluorescence studies. 2 A flu-like prodromal phase with a non-specific urticarial dermatitis may herald the development of the more characteristic tense bullae. 3 Obtaining a thorough medication history is important as a number of pharmacological agents have been reported to trigger this same phenomenon. We report a case of generalized BP induced by hydrochlorothiazide therapy in a 32-year-old male.
authors.forename: Catherine
authors.initials: C
authors.lastname: Warner
authors.forename: Young
authors.initials: Y
authors.lastname: Kwak
authors.forename: Mary H B
authors.initials: MH
authors.lastname: Glover
authors.forename: Loretta S
authors.initials: LS
authors.lastname: Davis
mesh_terms: D000328:Adult; D000906:Antibodies / Q000276:immunology; D000959:Antihypertensive Agents / Q000009:adverse effects*; D001485:Basement Membrane / Q000276:immunology; D006801:Humans; D006852:Hydrochlorothiazide / Q000009:adverse effects*; D008297:Male; D010391:Pemphigoid, Bullous / Q000139:chemically induced* / Q000276:immunology
chemical_list: D000906:Antibodies; D000959:Antihypertensive Agents; D006852:Hydrochlorothiazide