title: Adenovirus pneumonia presenting with nodular shadows on chest X-ray in two unrelated allogeneic bone marrow transplant recipients.
abstract: Adenoviruses are increasingly recognized as important pathogens following allogeneic stem cell transplantation. We herein report two cases of disseminated adenovirus infection that presented with nodular shadows on chest X-ray after allogeneic bone marrow transplantation from unrelated donors. Both patients died of respiratory failure. Autopsies revealed adenovirus infection of multiple organs. Adenovirus infection should be suspected when nodular lung lesions of unknown origin appear in allogeneic stem cell transplant recipients.
authors.affiliation: Department of Cellular Transplantation Biology, Division of Cancer Medicine, Kanazawa University Graduate School of Medical Science, Japan.
authors.forename: Kanako
authors.initials: K
authors.lastname: Mochizuki
authors.forename: Yukio
authors.initials: Y
authors.lastname: Kondo
authors.forename: Kohei
authors.initials: K
authors.lastname: Hosokawa
authors.forename: Kinya
authors.initials: K
authors.lastname: Ohata
authors.forename: Hirohito
authors.initials: H
authors.lastname: Yamazaki
authors.forename: Akiyoshi
authors.initials: A
authors.lastname: Takami
authors.forename: Motoko
authors.initials: M
authors.lastname: Sasaki
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Sato
authors.forename: Yasuni
authors.initials: Y
authors.lastname: Nakanuma
authors.forename: Shinji
authors.initials: S
authors.lastname: Nakao
mesh_terms: D000256:Adenoviridae; D000257:Adenoviridae Infections / Q000000981:diagnostic imaging* / Q000821:virology; D000328:Adult; D016026:Bone Marrow Transplantation; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011014:Pneumonia; D011024:Pneumonia, Viral / Q000000981:diagnostic imaging* / Q000821:virology; D013902:Radiography, Thoracic / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D066027:Transplant Recipients; D014184:Transplantation, Homologous