title: Biomimetic aerobic oxidative hydroxylation of arylboronic acids to phenols catalysed by a flavin derivative.
abstract: Flavin-catalysed oxidative hydroxylation of substituted arylboronic acids by molecular oxygen with the assistance of hydrazine or ascorbic acid resulted in phenols in high yields. This mild organocatalytic protocol is compatible with a variety of functional groups and it is alternatively usable for transformation of alkylboronic acids to alcohols. Reaction takes place also in water and fulfils criteria for a green procedure.
authors.affiliation: Department of Organic Chemistry, Institute of Chemical Technology, Prague, Technická 5, 16628 Prague 6, Czech Republic. cibulkar@vscht.cz.
authors.forename: Hana
authors.initials: H
authors.lastname: Kotoučová
authors.forename: Iveta
authors.initials: I
authors.lastname: Strnadová
authors.forename: Martina
authors.initials: M
authors.lastname: Kovandová
authors.forename: Josef
authors.initials: J
authors.lastname: Chudoba
authors.forename: Hana
authors.initials: H
authors.lastname: Dvořáková
authors.forename: Radek
authors.initials: R
authors.lastname: Cibulka
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D005415:Flavins / Q000737:chemistry*; D006900:Hydroxylation; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D010636:Phenols / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001897:Boronic Acids; D005415:Flavins; D010636:Phenols; D010100:Oxygen