title: Theranostic nanoparticles for cancer and cardiovascular applications.
abstract: Theranostics have received enormous attentions for individualized diagnosis and treatment in the past few years. Especially, the availability of various nanoplatforms provides great potentials for designing of sophisticated theranostic agents including imaging, targeting and therapeutic functions. Numerous reports have been published on how to construct multifunctional nanoparticles for the targeted diagnosis and therapy simultaneously since the concept of "theranostics". This review presents recent advances of molecular imaging and nanoplatform technology, and their applications in drug discovery and development. Applications of nanoplatform-based theranostics in cancer and cardiovascular diseases will also be covered including diagnosis, assessment of drug biodistribution, and visualization of drug release from nanoparticles, as well as monitoring of therapeutic effects.
authors.affiliation: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, People's Republic of China.
authors.forename: Dan
authors.initials: D
authors.lastname: Wang
authors.forename: Bingbing
authors.initials: B
authors.lastname: Lin
authors.forename: Hua
authors.initials: H
authors.lastname: Ai
mesh_terms: D000818:Animals; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000188:drug therapy*; D003952:Diagnostic Imaging / Q000379:methods; D006801:Humans; D050997:Nanomedicine / Q000379:methods; D053758:Nanoparticles / Q000627:therapeutic use*; D009369:Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*