title: [The influence of the intermittent hypoxia trainings on the functional status of corticoliberin- and beta-endorphin-synthesizing neurons of the paraventricular nucleus hypothalamus in rats].
abstract: The experiments show that hypoxia training leads to an increase of the immunoreactivity to corticotropin and beta-endorphin and to an increase of the content of these neuropeptides. In this case, the ratio of the area of the immunoreactive material to the corticotropin/beta-endorphin, and the coefficient of their content in the PVN did not change significantly compared with the control. Thus, the selected hypoxia mode leads to adaptation, which is reflected in the balanced activity of stress-realizing and stress-limiting systems of rats' hypothalamus.
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Kolesnyk
authors.forename: Ie V
authors.initials: IeV
authors.lastname: Kadzharian
authors.forename: A V
authors.initials: AV
authors.lastname: Abramov
mesh_terms: D000222:Adaptation, Physiological / Q000276:immunology; D000818:Animals; D003346:Corticotropin-Releasing Hormone / Q000096:biosynthesis*; D000860:Hypoxia / Q000276:immunology / Q000378:metabolism / Q000503:physiopathology*; D008297:Male; D009474:Neurons / Q000276:immunology / Q000378:metabolism / Q000502:physiology*; D010286:Paraventricular Hypothalamic Nucleus / Q000276:immunology / Q000378:metabolism / Q000503:physiopathology*; D051381:Rats; D017208:Rats, Wistar; D001615:beta-Endorphin / Q000096:biosynthesis*
chemical_list: D001615:beta-Endorphin; D003346:Corticotropin-Releasing Hormone