title: Preprocedural red blood cell distribution width predicts bare metal stent restenosis.
abstract: BACKGROUND
  It has been shown that increased red blood cell distribution width (RDW) predicts adverse outcomes in cardiovascular disease and in patients undergoing a percutaneous coronary intervention. The aim of the present study was to assess the predictive value of preinterventional RDW on the development of in-stent restenosis (ISR) in patients undergoing stent implantation.
  
  
  METHODS
  In this retrospective study, we compared 131 patients with ISR and 138 patients without ISR who had undergone bare metal stent implantation.
  
  
  RESULTS
  Preprocedural RDW was significantly higher in patients with ISR than those without restenosis (14.6±3.2 vs. 13.4±1.6%, P<0.001). Stent length was significantly longer in patients with than those without restenosis (17.9±5.6 vs. 16.2±5.2 mm, respectively, P=0.03). Compared with patients with restenosis, patients without restenosis had a lower rate of diabetes (28 vs. 61 patients, P=0.001), a significantly short period between two coronary angiographies (9.8±9.3 vs. 12.9±11.6 months, respectively, P=0.02), and lower triglyceride levels (133±53 vs. 198±121 mg/dl, respectively, P=0.05). In multivariate logistic regression analysis, diabetes mellitus, stent length, preprocedural RDW, and current smoking independently predicted ISR.
  
  
  CONCLUSIONS
  Increased preinterventional RDW significantly predicts bare metal stent restenosis and might represent a useful screening tool to stratify patients according to a higher or a lower risk of ISR after stent implantation in patients with stable and unstable angina pectoris.
authors.affiliation: aDepartment of Cardiology, Medical Park Hospital bDepartment of Cardiology, School of Medicine, Istanbul Medipol University, Istanbul cDepartment of Cardiology, School of Medicine, Kafkas University, Kars, Turkey.
authors.forename: Abdulmelik
authors.initials: A
authors.lastname: Yildiz
authors.forename: Fatih
authors.initials: F
authors.lastname: Tekiner
authors.forename: Ahmet
authors.initials: A
authors.lastname: Karakurt
authors.forename: Gokce
authors.initials: G
authors.lastname: Sirin
authors.forename: Dursun
authors.initials: D
authors.lastname: Duman
mesh_terms: D000368:Aged; D060050:Angina, Stable / Q000097:blood / Q000175:diagnosis / Q000628:therapy*; D000789:Angina, Unstable / Q000097:blood / Q000175:diagnosis / Q000628:therapy*; D016009:Chi-Square Distribution; D023903:Coronary Restenosis / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008670:Metals; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects* / Q000295:instrumentation*; D011237:Predictive Value of Tests; D011474:Prosthesis Design; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D008670:Metals