title: Inclusion complexation of phenoxyaliphatic acid derivatives of 3,3'-bis(indolyl)methanes with β-cyclodextrin.
abstract: The inclusion complexation behavior of phenoxyaliphatic acid derivatives of 3,3'-bis(indolyl)methane (BIMs 1-5) with β-cyclodextrin (β-CD) were investigated in both solution and solid state by means of UV-Visible, fluorescence spectroscopy, FT-IR and (1)H NMR techniques. The nature of the host-guest inclusion complex between BIMs and β-CD has been elucidated. The experimental results confirmed the existence of 1:1 inclusion complex of BIMs with β-CD. The binding constants describing the extent of formation of the complexes have been determined using Benesi-Hildebrand plots using UV-Vis and fluorescence spectroscopy. BIMs exhibited an affinity for β-CD. The spectral studies suggested the phenyl ring along with alkyl substitutions of BIMs is present inside of β-CD cavity.
authors.affiliation: Department of Chemistry, Manonmaniam Sundaranar University, Tirunelveli, 627 012, Tamilnadu, India, antonyphdchem@yahoo.com.
authors.forename: A
authors.initials: A
authors.lastname: Antony Muthu Prabhu
authors.forename: G S
authors.initials: GS
authors.lastname: Suresh Kumar
mesh_terms: D005227:Fatty Acids / Q000737:chemistry* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007211:Indoles / Q000737:chemistry* / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D010636:Phenols / Q000737:chemistry* / Q000378:metabolism; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D047392:beta-Cyclodextrins / Q000737:chemistry* / Q000378:metabolism
chemical_list: C512018:1,1-bis(3'-indolyl)methane; D005227:Fatty Acids; D007211:Indoles; D010636:Phenols; D047392:beta-Cyclodextrins; C042329:phenoxy radical