title: Development of P1 cortical auditory evoked potential in children presented with sensorineural hearing loss following cochlear implantation: a longitudinal study.
abstract: OBJECTIVE
  To assess the characteristics of P1 component in children presented with pre-lingual hearing loss, users of cochlear implants, and correlate them with speech perception performance.
  
  
  METHODS
  Ten children presented with pre-lingual sensory neural hearing loss using cochlear implants participated in this research. The cortical auditory evoked potential research was carried out with the /da/ speech stimulus, presented in free field, in three moments: at cochlear implant activation, with three and six months following activation. The Infant-Toddler Meaningful Auditory Integration Scale was used to verify the speech perception.
  
  
  RESULTS
  The correlation of the three moments of the test with the latency and the amplitude of P1 component through analysis of variance were observed. The comparison of latency and amplitude of P1 in each assessment moment was performed with Tukey's test. Wilcoxon and t-test showed that the score on the Infant-Toddler Meaningful Auditory Integration Scale increased significantly with the time of cochlear implant use, nevertheless with no correlation with the latency and amplitude of P1 component in the moments assessed, as demonstrated by Spearman's and Pearson's correlations.
  
  
  CONCLUSIONS
  The latency and amplitude of P1 component diminish as the time of cochlear implant use increases. However, there was no correlation between its development and speech perception performance.
authors.affiliation: Universidade de São Paulo, BauruSP, Brazil, Universidade de São Paulo - USP - Bauru (SP), Brazil.
authors.forename: Kátia de Freitas
authors.initials: Kde F
authors.lastname: Alvarenga
authors.affiliation: Universidade de São Paulo, BauruSP, Brazil, Universidade de São Paulo - USP - Bauru (SP), Brazil.
authors.forename: Leticia Cristina
authors.initials: LC
authors.lastname: Vicente
authors.affiliation: Universidade de São Paulo, BauruSP, Brazil, Universidade de São Paulo - USP - Bauru (SP), Brazil.
authors.forename: Raquel Caroline Ferreira
authors.initials: RC
authors.lastname: Lopes
authors.affiliation: Universidade de São Paulo, BauruSP, Brazil, Universidade de São Paulo - USP - Bauru (SP), Brazil.
authors.forename: Luzia Maria Pozzobom
authors.initials: LM
authors.lastname: Ventura
authors.affiliation: Universidade de São Paulo, BauruSP, Brazil, Universidade de São Paulo - USP - Bauru (SP), Brazil.
authors.forename: Maria Cecília
authors.initials: MC
authors.lastname: Bevilacqua
authors.affiliation: Universidade de São Paulo, BauruSP, Brazil, Universidade de São Paulo - USP - Bauru (SP), Brazil.
authors.forename: Adriane Lima Mortari
authors.initials: AL
authors.lastname: Moret
mesh_terms: D002675:Child, Preschool; D019929:Cochlear Implantation; D003054:Cochlear Implants; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D006319:Hearing Loss, Sensorineural / Q000534:rehabilitation* / Q000601:surgery; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D013067:Speech Perception / Q000502:physiology*