title: A simple small size and low cost sensor based on surface plasmon resonance for selective detection of Fe(III).
abstract: A simple, small size, and low cost sensor based on a Deferoxamine Self Assembled Monolayer (DFO-SAM) and Surface Plasmon Resonance (SPR) transduction, in connection with a Plastic Optical Fiber (POF), has been developed for the selective detection of Fe(III). DFO-SAM sensors based on appropriate electrochemical techniques can be frequently found in the scientific literature. In this work, we present the first example of a DFO-SAM sensor based on SPR in an optical fiber. The SPR sensing platform was realized by removing the cladding of a plastic optical fiber along half the circumference, spin coating a buffer of Microposit S1813 photoresist on the exposed core, and finally sputtering a thin gold film. The hydroxamate siderophore deferoxamine (DFO), having high binding affinity for Fe(III), is then used in its immobilized form, as self-assembled monolayer on the gold layer surface of the POF sensor. The results showed that the DFO-SAM-POF-sensor was able to sense the formation of the Fe(III)/DFO complex in the range of concentrations between 1 μm and 50 μm with a linearity range from 0 to 30 μm of Fe(III). The selectivity of the sensor was also proved by interference tests.
authors.affiliation: Department of Industrial and Information Engineering, Second University of Naples, Via Roma 29, Aversa 81031, Italy. nunzio.cennamo@unina2.it.
authors.forename: Nunzio
authors.initials: N
authors.lastname: Cennamo
authors.affiliation: Department of Chemistry, University of Pavia, Via Taramelli 12, Pavia 27100, Italy. galberti@unipv.it.
authors.forename: Giancarla
authors.initials: G
authors.lastname: Alberti
authors.affiliation: Department of Chemistry, University of Pavia, Via Taramelli 12, Pavia 27100, Italy. maria.pesavento@unipv.it.
authors.forename: Maria
authors.initials: M
authors.lastname: Pesavento
authors.affiliation: Department of Chemistry, University of Pavia, Via Taramelli 12, Pavia 27100, Italy. girolamo@unipv.it.
authors.forename: Girolamo
authors.initials: G
authors.lastname: D'Agostino
authors.affiliation: Department of Chemistry, University of Pavia, Via Taramelli 12, Pavia 27100, Italy. federico.quattrini01@universitadipavia.it.
authors.forename: Federico
authors.initials: F
authors.lastname: Quattrini
authors.affiliation: Department of Chemistry, University of Pavia, Via Taramelli 12, Pavia 27100, Italy. raffaela.biesuz@unipv.it.
authors.forename: Raffaela
authors.initials: R
authors.lastname: Biesuz
authors.affiliation: Department of Industrial and Information Engineering, Second University of Naples, Via Roma 29, Aversa 81031, Italy. luigi.zeni@unina2.it.
authors.forename: Luigi
authors.initials: L
authors.lastname: Zeni
mesh_terms: D003365:Costs and Cost Analysis; D003676:Deferoxamine / Q000032:analysis; D006046:Gold; D007501:Iron / Q000032:analysis*; D055100:Optical Fibers / Q000191:economics; D012015:Reference Standards; D013057:Spectrum Analysis; D020349:Surface Plasmon Resonance / Q000191:economics* / Q000295:instrumentation* / Q000592:standards
chemical_list: D006046:Gold; D007501:Iron; D003676:Deferoxamine