title: Palladium-catalyzed direct arylation of indoles with cyclohexanones.
abstract: A novel palladium catalyzed approach to 3-arylindoles was developed from indoles and cyclohexanones. Various cyclohexanones acted as aryl sources via an alkylation and dehydrogenation sequence using molecular oxygen as the hydrogen acceptor. This method showed good regioselectivity and afforded 3-arylindoles as the sole products.
authors.affiliation: Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education, College of Chemistry, Xiangtan University , Xiangtan 411105, China.
authors.forename: Shanping
authors.initials: S
authors.lastname: Chen
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Liao
authors.forename: Feng
authors.initials: F
authors.lastname: Zhao
authors.forename: Hongrui
authors.initials: H
authors.lastname: Qi
authors.forename: Saiwen
authors.initials: S
authors.lastname: Liu
authors.forename: Guo-Jun
authors.initials: GJ
authors.lastname: Deng
mesh_terms: D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003512:Cyclohexanones / Q000737:chemistry*; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D003512:Cyclohexanones; D006575:Heterocyclic Compounds, 3-Ring; D007211:Indoles; D010165:Palladium