title: Nutritional risk, nutritional status and incident disability in older adults. The FRADEA study.
abstract: OBJECTIVE
  To analyze if body mass index (BMI) and waist circumference (WC) as measures of nutritional status, and the Mini Nutritional Assessment Short Form (MNA-SF) as a nutritional risk measure are associated with increased risk of incident disability in basic activities of daily living (BADL) in a population based cohort of Spanish older adults.
  
  
  METHODS
  Concurrent cohort study.
  
  
  METHODS
  Albacete City, Spain.
  
  
  METHODS
  678 subjects over age 70 from the FRADEA Study (Frailty and Dependence in Albacete).
  
  
  METHODS
  BMI, WC and MNA-SF were recorded at the basal visit of the FRADEA Study. Incident disability in BADL was defined as loss of the ability to perform bathing, grooming, dressing, toilet use, or feeding from basal to follow-up visit, using the Barthel index. The association between nutritional status and nutritional risk with incident BADL disability was determined by Kaplan-Meier analysis and logistic regression adjusted for age, sex, basal function, comorbidity, cognitive decline, depression risk and frailty status.
  
  
  RESULTS
  Each point less of MNA-SF (OR 1.17, 95%CI 1.04-1.31) and MNA-SF<14 (OR 2.33, 95%CI 1.39-3.89), but not MNA-SF<12 (OR 1.47, 95%CI 0.89-2.42) had a greater adjusted risk of incident disability in BADL. Neither BMI (OR 1.02, 95%CI 0.97-1.06) nor WC (OR 1.01, 95%CI 0.99-1.03) were associated. Weight loss (OR 1.75, 95%CI 1.08-2.83) and mobility impairment (OR 3.35, 95%CI 1.67-6.73) remained as adjusted predictors of incident BADL disability, while anorexia almost reached the significance (OR 1.65, 95%CI 0.94-2.87).
  
  
  CONCLUSIONS
  Nutritional risk measured with the MNA-SF is associated with incident disability in BADL in older adults, while nutritional status measured with BMI or WC is not.
authors.affiliation: Pedro Abizanda Soler, Hospital Perpetuo Socorro, C/ Seminario 4, 02006 Albacete, Spain, Tel.: +34967597651, Fax: +34967597635, Email: pabizanda@sescam.jccm.es.
authors.forename: M
authors.initials: M
authors.lastname: Martínez-Reig
authors.forename: L
authors.initials: L
authors.lastname: Gómez-Arnedo
authors.forename: S A
authors.initials: SA
authors.lastname: Alfonso-Silguero
authors.forename: G
authors.initials: G
authors.lastname: Juncos-Martínez
authors.forename: L
authors.initials: L
authors.lastname: Romero
authors.forename: P
authors.initials: P
authors.lastname: Abizanda
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D000855:Anorexia / Q000453:epidemiology; D015992:Body Mass Index; D015331:Cohort Studies; D006233:Persons with Disabilities / Q000706:statistics & numerical data*; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D053208:Kaplan-Meier Estimate; D016015:Logistic Models; D008297:Male; D015596:Nutrition Assessment; D009752:Nutritional Status; D012306:Risk; D013030:Spain / Q000453:epidemiology; D055105:Waist Circumference; D015431:Weight Loss