title: Topographic assessment of retinal pigment epithelium detachment in central serous chorioretinopathy by three-dimensional optical coherence tomography single-layer retinal pigment epithelium map.
abstract: OBJECTIVE
  This study aims to compare the topographic distribution of retinal pigment epithelium detachment (PED) in central serous chorioretinopathy (CSC) on spectral domain optical coherence tomography (SD-OCT) single-layer retinal pigment epithelium (SL-RPE) map and fluorescein angiography for the first time.
  
  
  METHODS
  Twenty-seven eyes of CSC with PEDs were studied retrospectively. Topographic distribution of PEDs was documented on 50° fluorescein angiography and SD-OCT SL-RPE map on macular cube 512 × 128.
  
  
  RESULTS
  Quantity of PEDs ranged from 1 to 5 on SD-OCT SL-RPE map macular cube 512 × 128 and corresponding macular cube area on 50° fluorescein angiography. Topographic distribution of PEDs on SL-RPE map matched with PEDs on fluorescein angiography in the corresponding macular cube area, in all the cases (interobserver correlation = 0.9).
  
  
  CONCLUSIONS
  SD-OCT SL-RPE map is a noninvasive, three-dimensional advanced tool for documentation of topographic assessment of PEDs and obviates the need of fluorescein angiography for monitoring CSC.
authors.affiliation: Retina Service, Department of Ophthalmology, King George's Medical University, Lucknow, India ; Department of Ophthalmology, King George's Medical University, Lucknow, 226003 India.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Saxena
authors.affiliation: Department of Ophthalmology, Pallas Klinik, Olten, Switzerland.
authors.forename: Carsten H
authors.initials: CH
authors.lastname: Meyer
authors.affiliation: Retina Service, Department of Ophthalmology, King George's Medical University, Lucknow, India.
authors.forename: Shashi R
authors.initials: SR
authors.lastname: Sharma
keywords: Central serous chorioretinopathy; Fluorescein angiography; Pigment epithelium detachment; Single-layer retinal pigment epithelium map; Spectral domain optical coherence tomography