title: Information processing in the primate basal ganglia during sensory-guided and internally driven rhythmic tapping.
abstract: Gamma (γ) and beta (β) oscillations seem to play complementary functions in the cortico-basal ganglia-thalamo-cortical circuit (CBGT) during motor behavior. We investigated the time-varying changes of the putaminal spiking activity and the spectral power of local field potentials (LFPs) during a task where the rhythmic tapping of monkeys was guided by isochronous stimuli separated by a fixed duration (synchronization phase), followed by a period of internally timed movements (continuation phase). We found that the power of both bands and the discharge rate of cells showed an orderly change in magnitude as a function of the duration and/or the serial order of the intervals executed rhythmically. More LFPs were tuned to duration and/or serial order in the β- than the γ-band, although different values of preferred features were represented by single cells and by both bands. Importantly, in the LFPs tuned to serial order, there was a strong bias toward the continuation phase for the β-band when aligned to movements, and a bias toward the synchronization phase for the γ-band when aligned to the stimuli. Our results suggest that γ-oscillations reflect local computations associated with stimulus processing, whereas β-activity involves the entrainment of large putaminal circuits, probably in conjunction with other elements of CBGT, during internally driven rhythmic tapping.
authors.affiliation: Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Boulevard Juriquilla 3001, Querétaro, 76230, México.
authors.forename: Ramón
authors.initials: R
authors.lastname: Bartolo
authors.forename: Luis
authors.initials: L
authors.lastname: Prado
authors.forename: Hugo
authors.initials: H
authors.lastname: Merchant
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001479:Basal Ganglia / Q000166:cytology / Q000502:physiology*; D003344:Cortical Synchronization / Q000502:physiology*; D005583:Fourier Analysis; D008253:Macaca mulatta / Q000502:physiology*; D008297:Male; D008959:Models, Neurological; D009068:Movement / Q000502:physiology; D010507:Periodicity; D011597:Psychomotor Performance / Q000502:physiology*; D011699:Putamen / Q000166:cytology / Q000502:physiology
keywords: interval tuning; rhesus monkey; spikes and LFPs; synchronization-continuation task; timing