title: [Assessment of RBC transfusion volume and its effect on postoperative pulmonary complications in on-pump CABG patients].
abstract: This study was purposed to investigate the effect of the transfused RBC amount on pulmonary complications after on-pump CABG surgery, and to explore the influencing factors on RBC transfusion volume. 292 adult patients receiving on-pump CABG surgery were divided into non-RBC transfusion group (n = 71), 1-4 U RBC transfusion group (n = 144) and >4 U RBC transfusion group (n = 77). Adjusted multivariable regression analysis was performed to examine the correlation between transfused RBC amount and the odds of pulmonary complications, and multivariable linear regression was used to analyze the influencing factors on RBC transfusion volume. The results showed that compared the three groups, there was the significant difference in postoperative pulmonary complications (1.4% vs 14.6% vs 24.7%, P < 0.001). A stronger and graded correlation was found between transfused RBC amount and pulmonary complications in on-pump CABG patients, the adjusted odds were increased to 1.251 (95% CI: 1.120-1.398, P < 0.001), and influencing factors on RBC transfusion volume were as follows: age (B:0.102; 95% CI: 0.046-0.157, P < 0.001), sex (B:1.825; 95% CI: 0.692-2.957, P = 0.002), preoperative Hct (B:-36.044; 95% CI:-47.724--25.163, P < 0.001), CPB time (B: 0.031; 95% CI:0.013-0.050, P = 0.001) and acute myocardiac infarction (B:2.769; 95% CI: 1.295-4.243, P < 0.001). It is concluded that the transfused RBC amount is related with postoperative pulmonary complications, and the influencing factors on RBC transfusion volume include preoperative Hct, age, acute myocardiac infarction, sex and CPB time.
authors.affiliation: Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Wei
authors.affiliation: Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Zhuang
authors.affiliation: Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Lin-Feng
authors.initials: LF
authors.lastname: Chen
authors.affiliation: Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Li
authors.affiliation: Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Yu
authors.affiliation: Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Li-Guo
authors.initials: LG
authors.lastname: Zhu
authors.affiliation: Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Chao-Yun
authors.initials: CY
authors.lastname: Xi
authors.affiliation: Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China. E-mail:panmin1976@yahoo.com.cn.
authors.forename: Ji-Chun
authors.initials: JC
authors.lastname: Pan
authors.affiliation: Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China. E-mail: deqingw@vip.sina.come.
authors.forename: De-Qing
authors.initials: DQ
authors.lastname: Wang
mesh_terms: D001026:Coronary Artery Bypass; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011184:Postoperative Period; D065227:Transfusion Reaction