title: Tracheoplasty using the thymus against tracheo-esophageal fistula due to necrotizing tracheobronchitis in a very low birth weight infant.
abstract: We report a case of a very low birth weight infant treated successfully with tracheoplasty using the thymus against tracheo-esophageal fistula due to necrotizing tracheobronchitis. A baby boy was born at 31 weeks gestation with a birth body weight of 1,230 g. Suddenly on Day 19, his respiration deteriorated, and a flexible bronchofiberscopy showed tracheostenosis, tracheomalacia, and tracheal diverticula. On Day 21, his abdomen became significantly distended, and a flexible bronchofiberscopy showed a tracheo-esophageal fistula due to a rupture of the diverticula. On Day 105, during surgery, we confirmed necrosis of the trachea. Because the lesion was widespread, we used the thymus for tracheoplasty and closure of the tracheo-esophageal fistula. His post-operative course went well, and was discharged at 1 year 9 months of age. Now, 8 years after the operation, although he still needs a T-tube airway management through tracheostomy, he has achieved speech, normal growth and development, and takes regular classes at school. Tracheoplasty using the thymus is thought to be a treatment worth considering when there are no other effective alternative treatments for tracheo-esophageal fistula due to necrotizing tracheobronchitis.
authors.affiliation: Division of Neonatal Intensive Care, Tokyo Women's Medical University Medical Center East, Tokyo, Japan.
authors.forename: Hisaya
authors.initials: H
authors.lastname: Hasegawa
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Nagase
authors.forename: Miho
authors.initials: M
authors.lastname: Sakai
authors.forename: Nobuhide
authors.initials: N
authors.lastname: Henmi
authors.forename: Shio
authors.initials: S
authors.lastname: Tsuruta
mesh_terms: D001991:Bronchitis / Q000150:complications; D006801:Humans; D007223:Infant; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D008297:Male; D009336:Necrosis / Q000209:etiology; D013950:Thymus Gland / Q000601:surgery*; D014132:Trachea / Q000473:pathology / Q000601:surgery*; D014136:Tracheitis / Q000150:complications; D014138:Tracheoesophageal Fistula / Q000209:etiology / Q000601:surgery*
keywords: bronchoscopy; thymus; tracheo-esophageal fistula; tracheoplasty