title: [One case of hereditary angioneurotic laryngeal edema].
abstract: Hereditary angioneurotic laryngeal edema (HALE) is an autosomal dominant hereditary disease in which there is a decrease or defect in the C1 inhibitor (C1-INH). The pathophysiology of HALE is characterized by recurrent spontaneous episodes of transient edema of the laryngeal mucose and submucosal tissue with remission at irregular. Patients may die because of a life-threatening acute upper airway obstruction caused by laryngeal edema. HALE was diagnosed on the clinical symptoms, family history, and markedly decreased serum C1-INH activity and C1-INH protein.
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
authors.forename: Heying
authors.initials: H
authors.lastname: Yue
authors.forename: Hua
authors.initials: H
authors.lastname: Hu
mesh_terms: D054179:Angioedemas, Hereditary / Q000175:diagnosis*; D003174:Complement C1 Inactivator Proteins / Q000032:analysis / Q000378:metabolism; D050718:Complement C1 Inhibitor Protein; D006801:Humans; D007819:Laryngeal Edema / Q000175:diagnosis*; D012008:Recurrence
chemical_list: D003174:Complement C1 Inactivator Proteins; D050718:Complement C1 Inhibitor Protein; C469952:SERPING1 protein, human