title: Interim estimates of 2013/14 influenza clinical severity and vaccine effectiveness in the prevention of laboratory-confirmed influenza-related hospitalisation, Canada, February 2014.
abstract: During the 2013/14 influenza season in Canada, 631 of 654 hospitalisations for laboratory-confirmed influenza enrolled in sentinel hospitals were due to Influenza A. Of the 375 with known subtype, influenza A(H1N1) accounted for 357. Interim unmatched vaccine effectiveness adjusted for age and presence of one or more medical comorbidities was determined by test-negative case-control design to be 58.5% (90% confidence interval (CI): 43.9-69.3%) overall and 57.9% (90% CI: 37.7-71.5) for confirmed influenza A(H1N1).
authors.affiliation: Canadian Center for Vaccinology, IWK Health Centre and Capital Health, Dalhousie University, Halifax, Nova Scotia, Canada.
authors.forename: Sa
authors.initials: S
authors.lastname: McNeil
authors.forename: V
authors.initials: V
authors.lastname: Shinde
authors.forename: M
authors.initials: M
authors.lastname: Andrew
authors.forename: Tf
authors.initials: T
authors.lastname: Hatchette
authors.forename: J
authors.initials: J
authors.lastname: Leblanc
authors.forename: A
authors.initials: A
authors.lastname: Ambrose
authors.forename: G
authors.initials: G
authors.lastname: Boivin
authors.forename: Wr
authors.initials: W
authors.lastname: Bowie
authors.forename: F
authors.initials: F
authors.lastname: Diaz-Mitoma
authors.forename: M
authors.initials: M
authors.lastname: Elsherif
authors.forename: K
authors.initials: K
authors.lastname: Green
authors.forename: F
authors.initials: F
authors.lastname: Haguinet
authors.forename: S
authors.initials: S
authors.lastname: Halperin
authors.forename: B
authors.initials: B
authors.lastname: Ibarguchi
authors.forename: K
authors.initials: K
authors.lastname: Katz
authors.forename: J
authors.initials: J
authors.lastname: Langley
authors.forename: P
authors.initials: P
authors.lastname: Lagace-Wiens
authors.forename: B
authors.initials: B
authors.lastname: Light
authors.forename: M
authors.initials: M
authors.lastname: Loeb
authors.forename: J
authors.initials: J
authors.lastname: McElhaney
authors.forename: D
authors.initials: D
authors.lastname: Mackinnon-Cameron
authors.forename: Ae
authors.initials: A
authors.lastname: McCarthy
authors.forename: M
authors.initials: M
authors.lastname: Poirier
authors.forename: J
authors.initials: J
authors.lastname: Powis
authors.forename: D
authors.initials: D
authors.lastname: Richardson
authors.forename: M
authors.initials: M
authors.lastname: Semret
authors.forename: S
authors.initials: S
authors.lastname: Smith
authors.forename: D
authors.initials: D
authors.lastname: Smyth
authors.forename: G
authors.initials: G
authors.lastname: Stiver
authors.forename: S
authors.initials: S
authors.lastname: Trottier
authors.forename: L
authors.initials: L
authors.lastname: Valiquette
authors.forename: D
authors.initials: D
authors.lastname: Webster
authors.forename: L
authors.initials: L
authors.lastname: Ye
authors.forename: A
authors.initials: A
authors.lastname: McGeer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002170:Canada / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology / Q000302:isolation & purification*; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000276:immunology; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control* / Q000821:virology; D007753:Laboratories; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012621:Seasons; D018571:Sentinel Surveillance; D012720:Severity of Illness Index; D055815:Young Adult
chemical_list: D007252:Influenza Vaccines