title: Nanobiosensors: role in cancer detection and diagnosis.
abstract: The ability to detect many cancers at an early stage in its clinical course has the potential to improve patient outcomes in terms of morbidity and mortality. Nanosized components incorporated into existing clinical diagnostic and detection systems as well as novel nanobiosensors have demonstrated improved sensitivity and specificity compared with traditional cancer testing approaches. Nanoparticles, nanowires, nanotubes, and nanocantilevers are examples of four nanobiosensor systems that have been used experimentally in the context of detection and diagnosis of prostate, breast, pancreatic, lung, and brain cancers over the past few years. Nanobiosensors will begin to transition into clinically validated tests as experimental and engineering techniques advance. This paper presents examples of some such nanobiosensors for cancer diagnosis and detection.
authors.affiliation: Department of Molecular Biology and Immunology, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Gdowski
authors.forename: Amalendu P
authors.initials: AP
authors.lastname: Ranjan
authors.forename: Anindita
authors.initials: A
authors.lastname: Mukerjee
authors.forename: Jamboor K
authors.initials: JK
authors.lastname: Vishwanatha
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D006801:Humans; D053758:Nanoparticles; D036103:Nanotechnology / Q000379:methods*; D037742:Nanotubes, Carbon; D009369:Neoplasms / Q000175:diagnosis*; D045663:Quantum Dots
chemical_list: D037742:Nanotubes, Carbon