title: [Intraoperative margin evaluation in breast-conservation surgery using margin probe technique].
abstract: BACKGROUND
  The most important prognostic factor after breast conservation surgery is surgical margin involvement. In cases where surgical margins are involved, the patient must return to the OR for a second operation. Therefore, there is a need for an intra-operative tool to assess the surgical margins. The Margin Probe technique was developed for this need. In this article we present our experience at the "Barzilai" Medical Center using the Margin Probe during breast conservation surgery.
  
  
  METHODS
  The Margin Probe technique is added to routine standard of care at "Barzilai" Medical Center. The device sends radiofrequency signals to the resected tissue and spectroscopy analysis provides data to the surgeon about the involvement of the surgical margins. In cases where the device signals for positive margins, the surgeon expands the resection, in order to avoid a second surgery in the future.
  
  
  RESULTS
  From sixty four patients who underwent breast conservative surgery, twenty four (37.5%) underwent intraoperative additional re-excision due to positive margin signals from the Margin Probe device. From those patients, nine patients (37.5%) indeed had surgical margins involvement in the pathology analysis. From all patients, four (6.25%) underwent a second surgery, while only one patient had a false negative measurement from the device.
  
  
  CONCLUSIONS
  According to our experience, using the Margin Probe technique is feasible, safe and reduces the rate of repeated operation.
authors.affiliation: Department of General and Vascular Surgery, Barzilai Medical Center, Ashkelon affiliated with the Faculty of Health Sciences, Ben-Gurion University of the Negev.
authors.forename: Idit
authors.initials: I
authors.lastname: Melnik
authors.affiliation: Department of General and Vascular Surgery, Barzilai Medical Center, Ashkelon affiliated with the Faculty of Health Sciences, Ben-Gurion University of the Negev.
authors.forename: Ilia
authors.initials: I
authors.lastname: Lifshitz
authors.affiliation: Department of General and Vascular Surgery, Barzilai Medical Center, Ashkelon affiliated with the Faculty of Health Sciences, Ben-Gurion University of the Negev.
authors.forename: Pioter
authors.initials: P
authors.lastname: Weinshtein
authors.affiliation: Department of General and Vascular Surgery, Barzilai Medical Center, Ashkelon affiliated with the Faculty of Health Sciences, Ben-Gurion University of the Negev.
authors.forename: Boris
authors.initials: B
authors.lastname: Yoffe
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D005188:False Negative Reactions; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007430:Intraoperative Care / Q000379:methods*; D007557:Israel; D015412:Mastectomy, Segmental / Q000379:methods*; D008875:Middle Aged; D011846:Radio Waves; D012086:Reoperation / Q000706:statistics & numerical data; D013057:Spectrum Analysis / Q000379:methods*