title: Fabrication of carbonate apatite blocks from set gypsum based on dissolution-precipitation reaction in phosphate-carbonate mixed solution.
abstract: Carbonate apatite (CO3Ap), fabricated by dissolution-precipitation reaction based on an appropriate precursor, is expected to be replaced by bone according to bone remodeling cycle. One of the precursor candidates is gypsum because it shows self-setting ability, which then enables it to be shaped and molded. The aim of this study, therefore, was to fabricate CO3Ap blocks from set gypsum. Set gypsum was immersed in a mixed solution of 0.4 mol/L disodium hydrogen phosphate (Na2HPO4) and 0.4 mol/L sodium hydrogen carbonate (NaHCO3) at 80-200°C for 6-48 h. Powder X-ray diffraction patterns and Fourier transform infrared spectra showed that CO3Ap block was fabricated by dissolution-precipitation reaction in Na2HPO4-NaHCO3 solution using set gypsum in 48 h when the temperature was 100°C or higher. Conversion rate to CO3Ap increased with treatment temperature. CO3Ap block containing a larger amount of carbonate was obtained when treated at lower temperature.
authors.affiliation: Department of Biomaterials, Faculty of Dental Science, Kyushu University.
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Nomura
authors.forename: Kanji
authors.initials: K
authors.lastname: Tsuru
authors.forename: Michito
authors.initials: M
authors.lastname: Maruta
authors.forename: Shigeki
authors.initials: S
authors.lastname: Matsuya
authors.forename: Ichiro
authors.initials: I
authors.lastname: Takahashi
authors.forename: Kunio
authors.initials: K
authors.lastname: Ishikawa
mesh_terms: D001031:Apatites / Q000737:chemistry*; D002133:Calcium Sulfate; D002254:Carbonates / Q000737:chemistry*; D012995:Solubility; D012996:Solutions
chemical_list: D001031:Apatites; D002254:Carbonates; D012996:Solutions; D002133:Calcium Sulfate