title: Oral manifestations of allograft recipients before and after renal transplantation.
abstract: Renal transplantation is considered the best treatment option for patients with end-stage renal disease. In this study, the prevalence of oral lesions was studied in a cohort of renal transplant recipients before and after transplantation. Fifty-nine kidney transplant recipients were examined one week before and four months after transplantation. The information gathered included age, sex, smoking history, duration on dialysis, drugs and their doses. There were 41 males (69.5%) and 18 females (30.5%) with a mean age of 37 years. Before surgery, two patients had non-specific lesions and two other patients had leukoedema. Following transplantation, 24 patients (40.7%) did not have any specific lesion. In six patients, we observed non-specific erythematous lesions (10.2%). Other recorded observations are as follows: Gingival hyperplasia in five patients (8.5%), oral candidiasis of the erythematous type in five patients (8.5%), hairy leukoplakia in four patients (6.8%) and leukoedema in seven patients (11.9%). In our study patients, the prevalence of oral lesions increased after transplantation, although it was lower than that reported in other studies. This could be due to the differences in sample size, differences between Iranian race and other races and different pharmaceutical formulation of the drug produced in Iran.
authors.forename: Gita
authors.initials: G
authors.lastname: Rezvani
authors.forename: Mehdy
authors.initials: M
authors.lastname: Davarmanesh
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Azar
authors.forename: Mehdy
authors.initials: M
authors.lastname: Salehipour
authors.forename: Razieh
authors.initials: R
authors.lastname: Sedaghat
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Karimi
authors.forename: Neda
authors.initials: N
authors.lastname: Pazhoohi
authors.forename: Elham
authors.initials: E
authors.lastname: Ansari
authors.affiliation: Department of Oral and Maxillofacial Pathology, Biomaterial Research Center, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Ali Dehghani
authors.initials: AD
authors.lastname: Nazhvani
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D064591:Allografts; D002180:Candidiasis, Oral / Q000453:epidemiology / Q000235:genetics / Q000276:immunology*; D005260:Female; D020022:Genetic Predisposition to Disease; D005885:Gingival Hyperplasia / Q000453:epidemiology / Q000235:genetics / Q000276:immunology*; D006801:Humans; D007492:Iran / Q000453:epidemiology; D016030:Kidney Transplantation; D017733:Leukoplakia, Hairy / Q000453:epidemiology / Q000235:genetics; D008297:Male; D008875:Middle Aged; D055815:Young Adult