title: Effects of an eight-week resistance training on plasma vaspin concentrations, metabolic parameters levels and physical fitness in patients with type 2 diabetes.
abstract: Vaspin as a novel adipokine has insulin-sensitizing effects, which may be associated with decreased blood glucose concentration. In this study, we aimed to investigate the effects of resistance exercise training on plasma vaspin concentrations and its relation to plasma levels of insulin and glucose in patients with type 2 diabetes (T2D). In a quasi-experimental study, 18 male patients with T2D (mean age, 48.50 ± 7.73 years, mean weight, 79.41 ± 12.60 kg) were divided into 2 groups as follows: control (n=9), and resistance training (RT; n=9) groups. Resistance training was performed 3 times weekly for 8 weeks. Anthropometric, metabolic parameters and plasma vaspin levels were measured at baseline and at the end of study. Within-group data were analyzed with the paired t test, and between-group effects were analyzed with the independent t test. Waist-hip ratio (WHR), glucose, insulin of plasma and insulin resistance [homeostasis model assessment of insulin resistance (HOMA-IR) score] were all significantly decreased, whereas levels of vaspin and plasma lipids [cholesterol, triglycerides (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very low-density lipoproteins (VLDL)] showed no significant changes in RT group as compared with the related values of control groups. Serum vaspin levels did not correlate with anthropometric and metabolic parameters at the assigned times. Our findings suggest that 8-week of resistance training significantly improved insulin resistance index; however, this form of exercise failed to result in significant changes in serum vaspin concentration and lipid profiles. Further research is needed to investigate the role of vaspin in human physiology and to elucidate the effect(s) of exercise intervention on serum vaspin concentrations (Registration Number: IRCT2013060911772N1).
authors.affiliation: Department Of Exercise Physiology, Faculty of Physical Education and Sport Science, Islamic Azad University Sari Branch, Sari, Iran.
authors.forename: Hassan
authors.initials: H
authors.lastname: Amouzad Mahdirejei
authors.affiliation: Department Of Exercise Physiology, Faculty of Physical Education and Sport Science, Islamic Azad University Sari Branch, Sari, Iran.
authors.forename: Sajedeh
authors.initials: S
authors.lastname: Fadaei Reyhan Abadei
authors.affiliation: Department Of Exercise Physiology, Faculty of Physical Education and Sport Science, Islamic Azad University Sari Branch, Sari, Iran.
authors.forename: Arshin
authors.initials: A
authors.lastname: Abbaspour Seidi
authors.affiliation: Department Of Exercise Physiology, Faculty of Physical Education and Sport Science, Islamic Azad University Sari Branch, Sari, Iran.
authors.forename: Negar
authors.initials: N
authors.lastname: Eshaghei Gorji
authors.affiliation: Physical Education and Sport Science Faculty, Shomal Non-Governmental University, Amol, Iran.
authors.forename: Hassan
authors.initials: H
authors.lastname: Rahmani Kafshgari
authors.affiliation: Physical Education and Sport Science Faculty, Shomal Non-Governmental University, Amol, Iran.
authors.forename: Mostafa
authors.initials: M
authors.lastname: Ebrahim Pour
authors.affiliation: Department of Exercise Physiology, Faculty of Physical Education and Sport Science, University of Payam Noor Behshahr Branch, Behshahr, Iran.
authors.forename: Habib
authors.initials: H
authors.lastname: Bagheri Khalili
authors.affiliation: Physical Education and Sport Science Faculty, Shomal Non-Governmental University, Amol, Iran.
authors.forename: Farshad
authors.initials: F
authors.lastname: Hajeizad
authors.affiliation: Physical Education and Sport Science Faculty, Shomal Non-Governmental University, Amol, Iran.
authors.forename: Mohamad
authors.initials: M
authors.lastname: Khayeri
keywords: Lipid; Resistance Training; Type 2 Diabetes; Vaspin