title: Oesophageal angioleiomyosarcoma in a cat.
abstract: A female spayed domestic longhair cat aged 3 years and 9 months was referred for investigation of regurgitation and weight loss of 2 months' duration. Thoracic radiographs revealed a soft tissue mass within the cranial mediastinum causing focal oesophageal dilation. Computed tomography confirmed a contrast-enhancing mass located cranial to the heart base, possibly originating from the oesophagus. Exploratory thoracotomy revealed an intramural soft tissue mass within the ventral oesophageal wall. Surgical excision of the mass and reconstruction of the oesophagus around an oesophageal tube was performed successfully. Histopathological examination of the mass was compatible with a spindle cell tumour with a prominent vasoformative component. Immunohistochemistry was positive for α-smooth muscle actin and von Willebrand factor protein, and negative for CD117/c-kit protein. Both histopathological and immunohistochemical findings confirmed the diagnosis of an angioleiomyosarcoma. The cat was clinically well 6 months postoperatively. To our knowledge, this is the first report of an oesophageal angioleiomyosarcoma in a cat.
authors.affiliation: Department of Veterinary Clinical Sciences, Small Animal Medicine and Surgery Group, Queen Mother Hospital for Animals, Royal Veterinary College, Hatfield, UK lesley_thw@hotmail.com.
authors.forename: Lesley H W
authors.initials: LH
authors.lastname: Teo
authors.affiliation: Department of Pathology and Pathogen Biology, Royal Veterinary College, Hatfield, UK.
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Cahalan
authors.affiliation: Department of Veterinary Clinical Sciences, Small Animal Medicine and Surgery Group, Queen Mother Hospital for Animals, Royal Veterinary College, Hatfield, UK.
authors.forename: Livia
authors.initials: L
authors.lastname: Benigni
authors.affiliation: Department of Veterinary Clinical Sciences, Small Animal Medicine and Surgery Group, Queen Mother Hospital for Animals, Royal Veterinary College, Hatfield, UK.
authors.forename: Zoe
authors.initials: Z
authors.lastname: Halfacree
mesh_terms: D018229:Angiomyoma / Q000000981:diagnostic imaging / Q000601:surgery / Q000662:veterinary*; D000818:Animals; D002371:Cat Diseases / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002415:Cats; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery / Q000662:veterinary*; D004947:Esophagus / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging / Q000601:surgery / Q000662:veterinary*; D011859:Radiography; D013908:Thoracotomy / Q000662:veterinary