title: Levels of antioxidant substances, acute phase response and lipid peroxidation in the left and right abomasum displacement in cows.
abstract: The aim of the present study was to assess metabolic changes occurring in Holstein cows with left or right abomasal displacement. Total sialic acid (TSA) values of the left abomasal displacement (LDA) group were elevated significantly (p < 0.0001) as compared to the controls. In the LDA group, serum ceruloplasmin (CPN) and aspartate transaminase (AST) levels were increased significantly (p < 0.0001) as well. Compared to the control group, serum glutathione (GSH) level was decreased significantly in both LDA and right abomasal displacement (RDA) groups (p < 0.0001). Among the clinical examination parameters, rumen contraction rates were decreased in both LDA and RDA groups significantly (p < 0.0001). These results suggest that inflammatory and oxidative parameters might have taken part in the pathogenesis of abomasal displacement. In this regard, anti-cytokine and anti-oxidant therapies developed in human medicine may also play a potential therapeutic role in the fatty liver and abomasal displacement in cattle.
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University, 15030 Burdur, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Mamak
authors.affiliation: Department of Biochemistry, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University, 15030 Burdur, Turkey.
authors.forename: A K
authors.initials: AK
authors.lastname: Devrim
authors.affiliation: Department of Biochemistry, Faculty of Veterinary Medicine, Balikesir University, 10100 Balikesir, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Aksit
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Balikesir University, 10100 Balikesir, Turkey.
authors.forename: I
authors.initials: I
authors.lastname: Aytekin
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University, 15030 Burdur, Turkey.
authors.forename: R
authors.initials: R
authors.lastname: Yildiz
mesh_terms: D000018:Abomasum / Q000473:pathology*; D000210:Acute-Phase Reaction / Q000378:metabolism / Q000662:veterinary*; D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood / Q000378:metabolism*; D005260:Female; D015227:Lipid Peroxidation / Q000502:physiology*; D013272:Stomach Diseases / Q000097:blood / Q000378:metabolism / Q000662:veterinary*
chemical_list: D000975:Antioxidants