title: Three cases of imported dengue virus infection from Madeira to Belgium, 2012.
abstract: We report three laboratory-confirmed dengue virus (DENV) infections imported to Belgium by travelers returning from Madeira (Portugal). Despite the use of a mosquito-repellent spray as reported by two patients, the infection could not be prevented. Diagnosis was made by antigen detection and real-time reverse transcriptase polymerase chain reaction (RT-PCR) in two cases and by serology 1 month after onset of symptoms in a third one. The responsible virus was identified as DENV serotype 1, American/African genotype (genotype V). The close relationship to isolates from Colombia supports the previous findings that a South American strain originated the outbreak in Madeira in 2012.
authors.affiliation: Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
authors.forename: Lieselotte
authors.initials: L
authors.lastname: Cnops
authors.forename: Leticia
authors.initials: L
authors.lastname: Franco
authors.forename: Britt
authors.initials: B
authors.lastname: Van Meensel
authors.forename: Jef
authors.initials: J
authors.lastname: Van den Ende
authors.forename: Maria
authors.initials: M
authors.lastname: Paz Sanchez-Seco
authors.forename: Marjan
authors.initials: M
authors.lastname: Van Esbroeck
mesh_terms: D000328:Adult; D000818:Animals; D001530:Belgium / Q000453:epidemiology; D009033:Culicidae; D003715:Dengue / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007303:Insect Vectors; D008297:Male; D008875:Middle Aged; D011174:Portugal; D014195:Travel