title: Necrobiosis lipoidica.
abstract: BACKGROUND
  Necrobiosis lipoidica presents with a distinctive appearance making it an important clinical diagnosis.
  
  
  OBJECTIVE
  To describe a case of necrobiosis lipoidica in a patient with type 1 diabetes mellitus, and to discuss differential diagnoses and management.
  
  
  CONCLUSIONS
  Necrobiosis lipoidica is most commonly found on the shins, presenting as a well-defined plaque. Management is challenging and options are discussed. Avoiding ulceration is a key concern.
authors.affiliation: MD, is a dermatologist, Department of Dermatology, Ramon Y Cajal University Hospital, Madrid, Spain.
authors.forename: Emiliano
authors.initials: E
authors.lastname: Grillo
authors.forename: Daniel
authors.initials: D
authors.lastname: Rodriguez-Muñoz
authors.forename: Andrés
authors.initials: A
authors.lastname: González-Garcia
authors.forename: Pedro
authors.initials: P
authors.lastname: Jaén
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007871:Leg Ulcer / Q000209:etiology / Q000517:prevention & control; D009335:Necrobiosis Lipoidica / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D012307:Risk Factors; D016559:Tacrolimus / Q000627:therapeutic use*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus