title: Three new bioactive phenolic glycosides from Liparis odorata.
abstract: Chemical investigation of the ethanol extract from the whole plant Liparis odorata (Willd.) Lindl (orchid family) has led to the isolation of three new phenolic glycosides named liparisglycoside A-C (1-3) along with six known compounds (4-9). The structures of compounds were elucidated by means of extensive spectroscopic data analysis and comparison with the literature data. In addition, compounds 3 and 9 revealed inhibitory effects on lipopolysaccharide-stimulated nitric oxide production, and compounds 1, 3 and 9 displayed hypolipidaemic effects in in vitro bioassays.
authors.affiliation: a Pharmacy College, Jiangxi University of Traditional Chinese Medicine , 818 Xinwan Road, Nanchang 330004 , Jiangxi , P.R. China.
authors.forename: Bin
authors.initials: B
authors.lastname: Li
authors.forename: Hongdong
authors.initials: H
authors.lastname: Liu
authors.forename: Dongming
authors.initials: D
authors.lastname: Zhang
authors.forename: Xuewen
authors.initials: X
authors.lastname: Lai
authors.forename: Bo
authors.initials: B
authors.lastname: Liu
authors.forename: Xianghong
authors.initials: X
authors.lastname: Xu
authors.forename: Peng
authors.initials: P
authors.lastname: Xu
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000960:Hypolipidemic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D008070:Lipopolysaccharides / Q000494:pharmacology; D015394:Molecular Structure; D009569:Nitric Oxide / Q000096:biosynthesis; D029595:Orchidaceae / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
chemical_list: D004365:Drugs, Chinese Herbal; D006027:Glycosides; D000960:Hypolipidemic Agents; D008070:Lipopolysaccharides; D010636:Phenols; C000591574:liparisglycoside A; C000591577:liparisglycoside B; C000591575:liparisglycoside C; D009569:Nitric Oxide