title: Home-based treadmill training improved seminal quality in adults with type 2 diabetes.
abstract: OBJECTIVE
  This was the first study conducted to determine the influence of home-based treadmill training on seminal quality in adults with type 2 diabetes.
  
  
  METHODS
  Sixty sedentary adults with type 2 diabetes volunteered for the current study. Thirty were randomly allocated to the intervention group and performed a a 14-week, home-based, treadmill training program, 3 sessions per week, consisting of a warm-up (10-15min), 40min treadmill exercise at a work intensity of 55-70% of peak heart rate (increasing by 2.5% each two weeks) measured during a maximal treadmill test, and cooling-down (5-10min). The control group included 30, age and BMI matched adults with type 2 diabetes who did not take part in any training program. Seminal quality analysis included semen volume, sperm concentration, motility and normal morphologic features. Furthermore, total antioxidant status (TAS) as well as glutathione peroxidase (GPX) activity were assessed in seminal plasma. This protocol was approved by an Institutional Ethics Committee.
  
  
  RESULTS
  The home-based treadmill training significantly increased sperm concentration as well as percentages of total sperm motility and normal spermatozoa. Furthermore, TAS and GPX activity were increased after the completion of the training program. No significant changes in any of the measured variables were found in the control group.
  
  
  CONCLUSIONS
  Home-based treadmill training improved seminal quality in adults with type 2 diabetes. A secondary finding was that seminal antioxidant defense system was significantly increased after being exercised.
authors.affiliation: Departamento de Medicina, Facultad de Medicina, Universidad de Cádiz, Cádiz, España. Electronic address: manuel.rosetyrodriguez@uca.es.
authors.forename: M
authors.initials: M
authors.lastname: Rosety-Rodriguez
authors.affiliation: Departamento de Urología, Hospital Universitario Puerta del Mar, Cádiz, España.
authors.forename: J M
authors.initials: JM
authors.lastname: Rosety
authors.affiliation: Departamento de Medicina, Facultad de Medicina, Universidad de Cádiz, Cádiz, España.
authors.forename: G
authors.initials: G
authors.lastname: Fornieles
authors.affiliation: Facultad de Ciencias del Deporte, Universidad de Cádiz, Cádiz, España.
authors.forename: M A
authors.initials: MA
authors.lastname: Rosety
authors.affiliation: Departamento de Medicina, Facultad de Medicina, Universidad de Cádiz, Cádiz, España.
authors.forename: A J
authors.initials: AJ
authors.lastname: Diaz
authors.affiliation: Departamento de Anatomía Humana, Facultad de Medicina, Universidad de Cádiz, Cádiz, España.
authors.forename: I
authors.initials: I
authors.lastname: Rosety
authors.affiliation: Departamento de Ginecología, Hospital Universitario de Jerez, Cádiz, España.
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez-Pareja
authors.affiliation: Departamento de Anatomía Humana, Facultad de Medicina, Universidad de Cádiz, Cádiz, España.
authors.forename: M
authors.initials: M
authors.lastname: Rosety
authors.affiliation: Escuela de Medicina del Deporte, Universidad de Cádiz, Cádiz, España.
authors.forename: F J
authors.initials: FJ
authors.lastname: Ordonez
authors.affiliation: Facultad de Medicina, Universidad de Cádiz, Cádiz, España.
authors.forename: S
authors.initials: S
authors.lastname: Elosegui
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000628:therapy; D015444:Exercise; D006699:Home Care Services; D006801:Humans; D008297:Male; D055101:Semen Analysis
keywords: Antioxidant defense system; Defensas antioxidantes; Diabetes mellitus tipo 2; Ejercicio; Exercise; Semen; Type 2 diabetes mellitus