title: EuroSCORE II with SYNTAX score to assess risks of coronary artery bypass grafting outcomes.
abstract: OBJECTIVE
  We evaluated the usefulness of the combination of European System for Cardiac Operative Risk Evaluation score (EuroSCORE II) and SYNergy between percutaneous intervention with TAXus drug-eluting stents and cardiac surgery (SYNTAX) score in predicting risks associated with early and late outcomes after coronary artery bypass grafting (CABG).
  
  
  METHODS
  Between January 2010 and April 2012, 412 patients underwent isolated CABG at our institution. EuroSCORE II and SYNTAX score were calculated retrospectively, and their ability to predict early and long-term outcomes was evaluated. Patients were divided into four groups according to median EuroSCORE II and SYNTAX score: Group 1, low EuroSCORE II, low SYNTAX (n=103); Group 2, low EuroSCORE II, high SYNTAX (n=103); Group 3, high EuroSCORE II, low SYNTAX (n=99); and Group 4, high EuroSCORE II, high SYNTAX (n=107).
  
  
  RESULTS
  Operative death was not different among the groups; however, Group 4 had the highest major complication rate of the four groups (0 in Group 1, 2.9% in Group 2, 3.0% in Group 3 and 8.4% in Group 4; P=0.011). Multivariate analyses revealed that both high EuroSCORE II (odds ratio [OR]: 4.154; P=0.030) and high SYNTAX score (OR: 3.988; P=0.035) were independent predictors of postoperative major complications and that high EuroSCORE II was an independent predictor of late mortality (OR: 4.673; P=0.016) but high SYNTAX score was not (OR: 0.808; P=0.662). Actuarial survival rate at 3 years was the lowest in Group 4 (99.0±1.0% in Group 1, 97.7±1.6% in Group 2, 91.9±2.7% in Group 3 and 90.5±4.7% in Group 4; P=0.045).
  
  
  CONCLUSIONS
  The combination of EuroSCORE II and SYNTAX score was useful in predicting early major complications after CABG. In the long term, EuroSCORE II continued to be associated with late mortality, but SYNTAX score did not.
authors.affiliation: Department of Cardiovascular Surgery, Sakakibara Heart Institute, Tokyo, Japan tfukui.cvs@gmail.com.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Fukui
authors.affiliation: Department of Cardiovascular Surgery, Sakakibara Heart Institute, Tokyo, Japan.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Uchimuro
authors.affiliation: Department of Cardiovascular Surgery, Sakakibara Heart Institute, Tokyo, Japan.
authors.forename: Shuichiro
authors.initials: S
authors.lastname: Takanashi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000401:mortality*; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000601:surgery*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors
keywords: Coronary artery bypass grafting; Coronary artery bypass grafts; Risk analysis