title: Can the T-peak to T-end interval be a predictor of mortality in patients with ST-elevation myocardial infarction?
abstract: BACKGROUND
  The interval between the peak and the end of the T wave (Tp-e interval) on 12-lead ECG is a measure of transmural dispersion of repolarization and may be related to malignant ventricular arrhythmias. The objective of this study was to investigate whether the Tp-e interval predicts in-hospital and long-term mortality in patients with ST-segment elevation myocardial infarction (STEMI) undergoing a primary percutaneous coronary intervention (pPCI).
  
  
  METHODS
  This study included 488 consecutive patients with STEMI treated with pPCI. Electrocardiograms were obtained after pPCI and the Tp-e interval was measured in leads without ST-segment elevation.
  
  
  RESULTS
  There were 46 (9.4%) deaths in the population, with a mean follow-up time of 21.1±10.2 months. The Tp-e interval was associated with not only in-hospital ventricular tachycardia/fibrillation, target vessel revascularization, and death but also long-term target vessel revascularization and death. Furthermore, the Tp-e interval measured using the tail method was found to be a significant predictor of long-term mortality in multivariable Cox analyses [odds ratio 1.018, 95% confidence interval (1.004-1.033)]. Findings were similar in the Tp-e interval and the heart rate-corrected Tp-e interval (cTp-e).
  
  
  CONCLUSIONS
  Tp-e and cTp-e measured using the tail method were found to be predictors of both in-hospital and long-term mortality.
authors.affiliation: Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey.
authors.forename: Mustafa A
authors.initials: MA
authors.lastname: Tatlisu
authors.forename: Kazim S
authors.initials: KS
authors.lastname: Özcan
authors.forename: Bariş
authors.initials: B
authors.lastname: Güngör
authors.forename: Ahmet
authors.initials: A
authors.lastname: Ekmekçi
authors.forename: Elif I
authors.initials: EI
authors.lastname: Çekirdekçi
authors.forename: Emre
authors.initials: E
authors.lastname: Aruğarslan
authors.forename: Tufan
authors.initials: T
authors.lastname: Çinar
authors.forename: Ahmet
authors.initials: A
authors.lastname: Zengin
authors.forename: Mehmet
authors.initials: M
authors.lastname: Karaca
authors.forename: Mehmet
authors.initials: M
authors.lastname: Eren
authors.forename: Izzet
authors.initials: I
authors.lastname: Erdinler
mesh_terms: D000200:Action Potentials; D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology*; D017052:Hospital Mortality; D006801:Humans; D053208:Kaplan-Meier Estimate; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000401:mortality* / Q000503:physiopathology / Q000628:therapy; D016017:Odds Ratio; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects / Q000401:mortality; D011237:Predictive Value of Tests; D016016:Proportional Hazards Models; D012307:Risk Factors; D017180:Tachycardia, Ventricular / Q000209:etiology / Q000401:mortality / Q000503:physiopathology; D013997:Time Factors; D016896:Treatment Outcome; D014693:Ventricular Fibrillation / Q000209:etiology / Q000401:mortality / Q000503:physiopathology