title: Reporting of results from network meta-analyses: methodological systematic review.
abstract: OBJECTIVE
  To examine how the results of network meta-analyses are reported.
  
  
  METHODS
  Methodological systematic review of published reports of network meta-analyses.
  
  
  METHODS
  Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, Medline, and Embase, searched from inception to 12 July 2012.
  
  
  METHODS
  All network meta-analyses comparing the clinical efficacy of three or more interventions in randomised controlled trials were included, excluding meta-analyses with an open loop network of three interventions.
  
  
  METHODS
  The reporting of the network and results was assessed. A composite outcome included the description of the network (number of interventions, direct comparisons, and randomised controlled trials and patients for each comparison) and the reporting of effect sizes derived from direct evidence, indirect evidence, and the network meta-analysis.
  
  
  RESULTS
  121 network meta-analyses (55 published in general journals; 48 funded by at least one private source) were included. The network and its geometry (network graph) were not reported in 100 (83%) articles. The effect sizes derived from direct evidence, indirect evidence, and the network meta-analysis were not reported in 48 (40%), 108 (89%), and 43 (36%) articles, respectively. In 52 reports that ranked interventions, 43 did not report the uncertainty in ranking. Overall, 119 (98%) reports of network meta-analyses did not give a description of the network or effect sizes from direct evidence, indirect evidence, and the network meta-analysis. This finding did not differ by journal type or funding source.
  
  
  CONCLUSIONS
  The results of network meta-analyses are heterogeneously reported. Development of reporting guidelines to assist authors in writing and readers in critically appraising reports of network meta-analyses is timely.
authors.affiliation: Assistance Publique-Hôpitaux de Paris, Centre d'Epidémiologie Clinique, INSERM U1153, Hôpital Hôtel-Dieu, 75004 Paris, France.
authors.forename: Aïda
authors.initials: A
authors.lastname: Bafeta
authors.forename: Ludovic
authors.initials: L
authors.lastname: Trinquart
authors.forename: Raphaèle
authors.initials: R
authors.lastname: Seror
authors.forename: Philippe
authors.initials: P
authors.lastname: Ravaud
mesh_terms: D003299:Cooperative Behavior; D019317:Evidence-Based Medicine / Q000592:standards; D006801:Humans; D015201:Meta-Analysis as Topic; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data