title: [The effect of water with modified isotope content on the parameters of free radical oxidation in vivo].
abstract: With the use of nuclear magnetic resonance we investigated the effect of consumption of water with the modified isotope content on the composition of deuterium in the blood, assessed the state of pro-oxidant-antioxidant system in the blood and lyophilized tissues (liver, kidneys) under prolonged oxidative stress. Possible mechanisms of direct and indirect antioxidant effects of the water with modified isotope content and the perspectives of its use for nutritional correction of abnormalities of oxidative metabolism during special physiological conditions and in clinical practice are discussed.
authors.forename: A A
authors.initials: AA
authors.lastname: Basov
authors.forename: M G
authors.initials: MG
authors.lastname: Baryshev
authors.forename: S S
authors.initials: SS
authors.lastname: Dzhimak
authors.forename: I M
authors.initials: IM
authors.lastname: Bykov
authors.forename: R I
authors.initials: RI
authors.lastname: Sepiashvili
authors.forename: I I
authors.initials: II
authors.lastname: Pavliuchenko
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D003903:Deuterium / Q000032:analysis / Q000097:blood / Q000494:pharmacology; D005609:Free Radicals / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008900:Mineral Waters / Q000008:administration & dosage / Q000032:analysis; D018384:Oxidative Stress; D051381:Rats; D018461:Soft Tissue Infections / Q000097:blood*
chemical_list: D000975:Antioxidants; D005609:Free Radicals; D008900:Mineral Waters; D003903:Deuterium