title: Comparative study of emergence agitation between isoflurane and propofol anesthesia in adults after closed reduction of distal radius fracture.
abstract: Distal radius fracture is a common wound. It is reduced by surgery under anesthesia. Emergence agitation can often occur after anesthesia. It is associated with increased morbidity and hospital costs. However, there have been almost no reports in the medical literature on the occurrence of emergence agitation in adults. This study aimed to compare emergence agitation between isoflurane and propofol anesthesia in adults after closed reduction of distal radius fracture. Forty adults (ASA I-II) undergoing closed reduction of distal radius fracture were randomly assigned to either the isoflurane or propofol group and anesthesia was maintained with isoflurane or propofol. The bispectral index was monitored and maintained within 40-60. After reduction of fracture and fixation with plaster, patients were transported to the post-anesthetic care unit (PACU) and agitation state scale was checked by Aono's four-point scale (AFPS). AFPS score of 3 or 4 was considered to be emergence agitation. Pain scores were measured by the numeric rating scale (NRS) on arrival and at peak value at PACU. Eight (40.0%) patients in the isoflurane group and 2 (10.0%) patients in the propofol group developed emergence agitation (P = 0.031). There was no correlation between peak NRS and AFPS. Propofol may decrease the incidence of emergence agitation compared to isoflurane in adults undergoing closed reduction of distal radius fracture.
authors.affiliation: Department of Anesthesiology and Pain Medicine, Liaocheng People's Hospital, Liaocheng, China.
authors.forename: G Y
authors.initials: GY
authors.lastname: Liu
authors.affiliation: Department of Anesthesiology and Pain Medicine, Liaocheng People's Hospital, Liaocheng, China chenzhenqiangcn@126.com.
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Chen
authors.affiliation: Department of Anesthesiology and Pain Medicine, Liaocheng People's Hospital, Liaocheng, China.
authors.forename: Z W
authors.initials: ZW
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000758:Anesthesia; D003710:Demography; D005260:Female; D006801:Humans; D007530:Isoflurane / Q000009:adverse effects / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D019990:Perioperative Care; D011182:Postoperative Care; D011183:Postoperative Complications / Q000209:etiology; D015742:Propofol / Q000009:adverse effects / Q000494:pharmacology*; D011595:Psychomotor Agitation / Q000150:complications*; D011885:Radius Fractures / Q000150:complications* / Q000601:surgery*
chemical_list: D007530:Isoflurane; D015742:Propofol