title: Mango peel pectin as a carrier for solid dispersions.
abstract: OBJECTIVE
  The present study describes the evaluation of pectin as a carrier for solid dispersion.
  
  
  METHODS
  Pectin was extracted from mango peel. Solid dispersions were prepared by using pectin to enhance the dissolution rate of the drug. Aceclofenac was used as the model drug.
  
  
  RESULTS
  Solid dispersion containing pectin had comparatively less release of the drug as compared to lactose for a particular time period.
  
  
  CONCLUSIONS
  The slower release may be due to the solubility of pectin in an aqueous fluid and it's swelling capacity. With that in mind, it can be used as a carrier to prepare solid dispersions.
authors.affiliation: Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut, India.
authors.forename: Shobhit
authors.initials: S
authors.lastname: Kumar
authors.affiliation: Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut, India.
authors.forename: Satish Kumar
authors.initials: SK
authors.lastname: Gupta
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D002152:Calorimetry, Differential Scanning; D002626:Chemistry, Pharmaceutical; D004008:Diclofenac / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004337:Drug Carriers; D004339:Drug Compounding; D005079:Excipients / Q000737:chemistry; D031022:Mangifera / Q000737:chemistry*; D010368:Pectins / Q000737:chemistry* / Q000302:isolation & purification*; D012995:Solubility; D013607:Tablets / Q000737:chemistry*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004337:Drug Carriers; D005079:Excipients; D013607:Tablets; D004008:Diclofenac; D010368:Pectins; C056498:aceclofenac