title: The titanium PV I endosteal implant from beta-titanium alloy Ti 38Nb 6Ta.
abstract: OBJECTIVE
  The aim of this study was to use the beta-titanium alloy Ti38Nb6Ta for production of a new construction line of implants, perform testing on animals and preclinical tests.
  
  
  METHODS
  Within this study, a new PV I implant with five construction variants was developed. The implant includes three types of threads - microthreads and flat threads of two types with a different depth. Further, the PV I implant was tested on minipigs. Subsequently, preclinical tests of 150 implants were performed and assessed. The age interval of patients was from 18 to 74 years.
  
  
  RESULTS
  Beta titanium alloy exhibited higher strength than titanium alloys. Anti-corrosion resistance was also higher. The implant from beta-alloy was inserted in the tibias of minipigs. Sections showed good osseointegration of the PV I implant. During the preclinical tests, 150 implants were inserted with the success rate of 99.33% after the two year assessment. The assessment also included handicapped patients who are not usually assessed in classical studies. Finally, the implantation protocol and documentation of a new implantation system PV I was designed. At the same time the industrial sample of this implant was formed and accepted.
  
  
  CONCLUSIONS
  A new anti-rotation PV I implant with microthreads and conical anchorage of the abutment into the fixture was formed. The beta-titanium alloy Ti38Nb6Ta used for the implant was biocompatible and had higher mechanical and physical properties than the existing titanium alloys. The PV I implant was recommended for clinical application.
authors.affiliation: Clinic of Stomatology, Faculty of Medicine, Masaryk University, Brno and St. Anne's University Hospital in Brno, Czech Republic.
authors.forename: Patrik
authors.initials: P
authors.lastname: Prachar
authors.affiliation: Clinic of Stomatology, Faculty of Medicine, Masaryk University, Brno and St. Anne's University Hospital in Brno, Czech Republic.
authors.forename: Sonia
authors.initials: S
authors.lastname: Bartakova
authors.affiliation: Clinic of Stomatology, Faculty of Medicine, Masaryk University, Brno and St. Anne's University Hospital in Brno, Czech Republic.
authors.forename: Jiri
authors.initials: J
authors.lastname: Vanek
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015921:Dental Implants; D006233:Persons with Disabilities; D006801:Humans; D007575:Jaw, Edentulous / Q000601:surgery; D008422:Materials Testing; D008875:Middle Aged; D011474:Prosthesis Design; D014025:Titanium / Q000494:pharmacology*; D055815:Young Adult
chemical_list: D015921:Dental Implants; C023988:beta titanium; D014025:Titanium
keywords: anti-rotation feature; beta-titanium alloy; handicapped patient; microthreads