title: A ligation DNAzyme-induced magnetic nanoparticles assembly for ultrasensitive detection of copper ions.
abstract: A novel biosensor for ultrasensitive detection of copper (Cu(2+)) was established based on the assembly of magnetic nanoparticles induced by the Cu(2+)-dependent ligation DNAzyme. With a low limit of detection of 2.8 nM and high specificity, this method has the potential to serve as a general platform for the detection of heavy metal ions.
authors.affiliation: State Key Lab of Food Science and Technology, School of Food Science and Technology, Jiangnan University , Wuxi, Jiangsu 214122, China.
authors.forename: Honghong
authors.initials: H
authors.lastname: Yin
authors.forename: Hua
authors.initials: H
authors.lastname: Kuang
authors.forename: Liqiang
authors.initials: L
authors.lastname: Liu
authors.forename: Liguang
authors.initials: L
authors.lastname: Xu
authors.forename: Wei
authors.initials: W
authors.lastname: Ma
authors.forename: Libing
authors.initials: L
authors.lastname: Wang
authors.forename: Chuanlai
authors.initials: C
authors.lastname: Xu
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D003300:Copper / Q000032:analysis*; D021881:DNA, Catalytic / Q000737:chemistry* / Q000235:genetics; D060766:Drinking Water / Q000032:analysis*; D007477:Ions / Q000032:analysis; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D012680:Sensitivity and Specificity; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D021881:DNA, Catalytic; D060766:Drinking Water; D007477:Ions; D058185:Magnetite Nanoparticles; D014874:Water Pollutants, Chemical; D003300:Copper