title: Vastus lateralis exhibits non-homogenous adaptation to resistance training.
abstract: BACKGROUND
  Variations in transverse point of measure on the vastus lateralis (VL) may significantly affect the relationship between structure and function. The purpose of this study was to compare changes in muscle architecture at 2 commonly used points of measure (VL0 and VL5).
  
  
  METHODS
  Maximal strength (1-repetition maximum [1RM] barbell squat) and muscle architecture were assessed PRE and POST 15 weeks of periodized resistance training. VL0 was 50% of the straight line distance between the greater trochanter and lateral epicondyle of the femur. VL5 was 5cm medial to VL0.
  
  
  RESULTS
  Increases in 1RM strength (3.7 ± 2.4 kg; P = 0.004) were observed. Changes in muscle thickness (MT) at VL5 were significantly greater than at VL0 (P = 0.006). Changes in strength correlated with changes in muscle architecture at VL0 only (MT: r = 0.561; fascicle length: r = 0.503).
  
  
  CONCLUSIONS
  Changes in muscle architecture appear to occur in a non-homogeneous manner.
authors.affiliation: Institute of Exercise Physiology and Wellness, University of Central Florida (UCF), 4000 Central Florida Blvd, Orlando, Florida, 32816, USA.
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Wells
authors.forename: David H
authors.initials: DH
authors.lastname: Fukuda
authors.forename: Jay R
authors.initials: JR
authors.lastname: Hoffman
authors.forename: Adam M
authors.initials: AM
authors.lastname: Gonzalez
authors.forename: Adam R
authors.initials: AR
authors.lastname: Jajtner
authors.forename: Jeremy R
authors.initials: JR
authors.lastname: Townsend
authors.forename: Gerald T
authors.initials: GT
authors.lastname: Mangine
authors.forename: Maren S
authors.initials: MS
authors.lastname: Fragala
authors.forename: Jeffrey R
authors.initials: JR
authors.lastname: Stout
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D000293:Adolescent; D000886:Anthropometry; D005260:Female; D006801:Humans; D053580:Muscle Strength / Q000502:physiology*; D052097:Quadriceps Muscle / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology*; D055070:Resistance Training; D013223:Statistics as Topic; D014463:Ultrasonography; D055815:Young Adult
keywords: fascicle length; resistance training; strength; transverse muscle adaptation; ultrasound