title: Study of Aetiology and Anti-biogram of Uropathogens in Children-A Retrospective Analysis.
abstract: OBJECTIVE
  Urinary Tract Infections (UTIs) are the most common serious bacterial infections which are seen during infancy. The aim of the present study was to evaluate aetiology, and antimicrobial resistance patterns among infants and children who approached our hospital for treatment of UTIs.
  
  
  METHODS
  In this observational study which was carried out from 2007 to 2010, 1575 urine samples which were collected from children with suspected UTIs were studied. Demographic characteristics, aetiological agents and antimicrobial resistance were evaluated.
  
  
  RESULTS
  UTIs were more common in the 0-1 year age group, among males. Among females, UTIs were commonly seen after 2 years of life. The most common isolated pathogen was Escherichia coli spp (45.12%), followed by Klebsiella spp (18.17%) and Enterococcus spp (9.23%). Isolated pathogens were highly resistant to ampicillin, co-trimoxazole, and norfloxacin (82%-98%) and highly sensitive to gentamicin (83%),amikacin (76.5%), and nitrofurantoin (71.5%).
  
  
  CONCLUSIONS
  The most common pathogen which caused UTIs in children was E. coli spp. The isolated pathogens were highly resistant to commonly used antibiotics, ampicillin and co-trimoxazole, while they were highly sensitive to gentamicin, amikacin and nitrofurantoin. So, these antibiotics may be used as alternative drug therapies for the treatment of UTIs.
authors.affiliation: Assistant Professor, Department of Microbiology, Kashibai Navale Medical College and General Hospital , Pune, Maharashtra, India .
authors.forename: Dnyaneshwari Purushottam
authors.initials: DP
authors.lastname: Ghadage
authors.affiliation: Professor & Head, Department of Microbiology, Kashibai Navale Medical College and General Hospital , Pune, Maharashtra, India .
authors.forename: Swati Shivajirao
authors.initials: SS
authors.lastname: Nale
authors.affiliation: Tutor, Department of Microbiology, Kashibai Navale Medical College and General Hospital , Pune, Maharashtra, India .
authors.forename: Deepali Shivajirao
authors.initials: DS
authors.lastname: Kamble
authors.affiliation: Professor, Department of Microbiology, Kashibai Navale Medical College and General Hospital , Pune, Maharashtra, India .
authors.forename: Vrushali Avinash
authors.initials: VA
authors.lastname: Muley
authors.affiliation: Assistant Professor, Department of Microbiology, Kashibai Navale Medical College and General Hospital , Pune, Maharashtra, India .
authors.forename: Archana Bhimrao
authors.initials: AB
authors.lastname: Wankhade
authors.affiliation: Assistant Professor, Department of Microbiology, Kashibai Navale Medical College and General Hospital , Pune, Maharashtra, India .
authors.forename: Rupali Jotiba
authors.initials: RJ
authors.lastname: Mali
authors.affiliation: Dean, Smt. Kashibai Navale Medical College and General Hospital , Pune, Maharashtra .
authors.forename: Arvind Vamanrao
authors.initials: AV
authors.lastname: Bhore
keywords: Antibiotic resistance; Escherichia coli; Sensitivity; Urinary tract infection