title: Asymmetric chlorination/ring expansion for the synthesis of α-quaternary cycloalkanones.
abstract: A highly enantioselective chlorination/ring expansion cascade for the construction of cycloalkanones with an all-carbon quaternary center was realized (up to 97% ee). Oxa-cyclobutanol substrates were employed for the first time in the ring expansion reactions, affording the functionalized dihydrofuranones in excellent enantioselectivity.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Lu, Shanghai 200032, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Yin
authors.forename: Shu-Li
authors.initials: SL
authors.lastname: You