title: Measurement of charged particle yields from PMMA irradiated by a 220 MeV/u (12)C beam.
abstract: The radiation used in hadrontherapy treatments interacts with the patient body producing secondary particles, either neutral or charged, that can be used for dose and Bragg peak monitoring and to provide a fast feedback on the treatment plans. Recent results obtained from the authors on simplified setups (mono-energetic primary beams interacting with homogeneous tissue-like target) have already indicated the correlation that exists between the flux of these secondaries coming from the target (e.g. protons and photons) and the position of the primary beam Bragg peak. In this paper, the measurements of charged particle fluxes produced by the interaction of a 220 MeV/u carbon ion beam at GSI, Darmstadt, with a polymethyl methacrylate target are reported. The emission region of protons (p), deuterons (d) and tritons (t) has been characterized using a drift chamber while the particle time-of-flight, used to compute the kinetic energy spectra, was measured with a LYSO scintillator. The energy released in the LYSO crystal was used for particle identification purposes. The measurements were repeated with the setup at 60° and 90° with respect to the primary beam direction. The accuracy on the fragments emission profile reconstruction and its relationship with the Bragg peak position have been studied. Based on the acquired experimental evidence, a method to monitor the dose profile and the position of the Bragg peak inside the target is proposed.
authors.affiliation: Laboratori Nazionali di Frascati dell'INFN, Frascati, Italy. Dipartimento di Scienze di Base e Applicate per Ingegneria, Sapienza Università di Roma, Roma, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Piersanti
authors.forename: F
authors.initials: F
authors.lastname: Bellini
authors.forename: F
authors.initials: F
authors.lastname: Bini
authors.forename: F
authors.initials: F
authors.lastname: Collamati
authors.forename: E
authors.initials: E
authors.lastname: De Lucia
authors.forename: M
authors.initials: M
authors.lastname: Durante
authors.forename: R
authors.initials: R
authors.lastname: Faccini
authors.forename: F
authors.initials: F
authors.lastname: Ferroni
authors.forename: S
authors.initials: S
authors.lastname: Fiore
authors.forename: E
authors.initials: E
authors.lastname: Iarocci
authors.forename: C
authors.initials: C
authors.lastname: La Tessa
authors.forename: M
authors.initials: M
authors.lastname: Marafini
authors.forename: I
authors.initials: I
authors.lastname: Mattei
authors.forename: V
authors.initials: V
authors.lastname: Patera
authors.forename: P G
authors.initials: PG
authors.lastname: Ortega
authors.forename: A
authors.initials: A
authors.lastname: Sarti
authors.forename: C
authors.initials: C
authors.lastname: Schuy
authors.forename: A
authors.initials: A
authors.lastname: Sciubba
authors.forename: M
authors.initials: M
authors.lastname: Vanstalle
authors.forename: C
authors.initials: C
authors.lastname: Voena
mesh_terms: D002244:Carbon / Q000627:therapeutic use*; D009010:Monte Carlo Method; D019904:Polymethyl Methacrylate; D011874:Radiometry / Q000379:methods*
chemical_list: D002244:Carbon; D019904:Polymethyl Methacrylate