title: Tiered approach revisited: introducing stage-appropriate or assay-appropriate scientific validation.
authors.affiliation: Bioanalysis Department, Janssen R&D, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30. ptimmerm@its.jnj.com.
authors.forename: Philip
authors.initials: P
authors.lastname: Timmerman
mesh_terms: D001681:Biological Assay / Q000379:methods* / Q000592:standards*; D015415:Biomarkers / Q000032:analysis*; D054316:Biomarkers, Pharmacological / Q000032:analysis / Q000378:metabolism; D006801:Humans; D004364:Pharmaceutical Preparations / Q000032:analysis / Q000378:metabolism; D015203:Reproducibility of Results
chemical_list: D015415:Biomarkers; D054316:Biomarkers, Pharmacological; D004364:Pharmaceutical Preparations