title: Cryptococcal rib osteomyelitis as primary and only symptom of idiopathic CD4 penia.
abstract: A 59-year old man with idiopathic CD4 lymphopenia presented with extensive disseminated Cryptococcus neoformans infection including a large rib cryptoccocoma, vertebral spondylitis and pleural empyema. Complete resection of the affected part of the rib was necessary after failure of initial antifungal treatment. The vertebral spondylitis has been successfully managed at 3 years of follow-up by continuous itraconazole treatment and regular MRI combined with leucocyte scintigraphy assessment.
authors.affiliation: Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen O, Denmark.
authors.forename: Rebecca A
authors.initials: RA
authors.lastname: Legarth
authors.affiliation: Department of Thoracic Surgery, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen O, Denmark.
authors.forename: Merete
authors.initials: M
authors.lastname: Christensen
authors.affiliation: Department of Microbiology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen O, Denmark.
authors.forename: Henrik
authors.initials: H
authors.lastname: Calum
authors.affiliation: Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen O, Denmark.
authors.forename: Terese L
authors.initials: TL
authors.lastname: Katzenstein
authors.affiliation: Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen O, Denmark.
authors.forename: Jannik
authors.initials: J
authors.lastname: Helweg-Larsen
keywords: C. neoformans; Cryptococcoma; Idiopathic CD4 penia; Spondylitis