title: Health-related quality of life after cardiac surgery--the effects of age, preoperative conditions and postoperative complications.
abstract: BACKGROUND
  Factors influencing the postoperative health-related quality of life (HRQOL) after cardiac surgery have not been well described yet, mainly in the older people. The study's aim was to explore differences in clinical conditions and HRQOL of patients before and after cardiac surgery taking into account the influence of age and to describe factors influencing changes of HRQOL in the postoperative period.
  
  
  METHODS
  This was a prospective consecutive observational study with two measurements using the SF-36 questionnaire before surgery and 1 year after surgery. It considered main clinical characteristics of participants prior to surgery as well as postoperative complications.
  
  
  RESULTS
  At baseline assessment the study considered 310 patients, predominantly male (69%). Mean age was 65 (SD 10.4) years and 101 patients (33%), who were older than 70, constituted the older group. This older group showed greater comorbidity, higher cardiac operative risk and lower HRQOL in the preoperative period as well as a higher prevalence of postoperative complications than the younger group. Thirty-day mortality was 1.4% in the younger group and 6.9% in the older group (p < 0.001). One year mortality was 3.3% in the younger group and 10.9% in the older group (p < 0.001). There was a significant improvement in all 8 health domains of the SF-36 questionnaire (p < 0.001) in the overall sample. There was no significant difference in change in a majority of HRQOL domains between the younger and the older group (p > 0.05). Logistic multivariate analysis identified a higher values of preoperative PCS (Physical component summary) scores (OR 1.03, CI 1.00 - 1.05, p = 0.0187) and MCS (Mental component summary) scores (OR 1.02, CI 0.997 - 1.00, p = 0.0846) as the only risk factors for potential non-improvement of HRQOL after cardiac surgery after correction for age, gender and type of surgery.
  
  
  CONCLUSIONS
  Older patients with higher operative risk have lower preoperative HRQOL but show a similar improvement in a majority of HRQOL domains after cardiac surgery as compared with younger patients. The multivariate analysis has shown the higher preoperative HRQOL status as a only significant factor of potential non-improvement of postoperative HRQOL.
authors.affiliation: Cardiac Surgery Department, BoŽeny Němcové str, 54, Hospital České Budějovice, České Budějovice, Czech Republic. vojtech.kurfirst@post.cz.
authors.forename: Vojtěch
authors.initials: V
authors.lastname: Kurfirst
authors.forename: Aleš
authors.initials: A
authors.lastname: Mokráček
authors.forename: Martina
authors.initials: M
authors.lastname: Krupauerová
authors.forename: Júlia
authors.initials: J
authors.lastname: Canádyová
authors.forename: Alan
authors.initials: A
authors.lastname: Bulava
authors.forename: Ladislav
authors.initials: L
authors.lastname: Pešl
authors.forename: Věra
authors.initials: V
authors.lastname: Adámková
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000523:psychology; D057234:Preoperative Period; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology*; D011795:Surveys and Questionnaires