title: A case of corneal endothelial dysfunction due to coxsackievirus A24 corneal endotheliitis after cataract surgery.
abstract: OBJECTIVE
  Corneal endotheliitis causes endothelial decompensation and is associated with significant visual impairment. The goal of this article is to report a case of corneal endotheliitis associated with coxsackievirus A24 infection after cataract surgery in a patient who had no previous symptoms indicative of conjunctivitis.
  
  
  METHODS
  A 55-year-old man was admitted for cataract surgery when acute hemorrhagic conjunctivitis was prevalent. Because he did not show any signs of suspected conjunctivitis, the cataract surgery was performed. No intraoperative complications occurred, and he was discharged 1 day after the surgery. Three days later, he visited our clinic with complaints of ocular pain and decreased vision in the left eye. Slit-lamp examination showed corneal stromal edema and mild inflammatory reaction in the anterior chamber. On postoperative day 7, anterior chamber irrigation and viral culture from the aqueous humor sample were performed.
  
  
  RESULTS
  Coxsackievirus A24 was detected in the viral culture. Electron photomicroscopic examination with immunohistochemical staining confirmed the presence of viral antigen.
  
  
  CONCLUSIONS
  This is the first report of corneal endotheliitis caused by coxsackievirus A24 confirmed by viral antigen detection in the aqueous humor of an affected eye.
authors.affiliation: Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Dong Hui
authors.initials: DH
authors.lastname: Lim
authors.forename: Jaeryung
authors.initials: J
authors.lastname: Kim
authors.forename: Jung Hye
authors.initials: JH
authors.lastname: Lee
authors.forename: Eui-Sang
authors.initials: ES
authors.lastname: Chung
authors.forename: Tae-Young
authors.initials: TY
authors.lastname: Chung
mesh_terms: D000956:Antigens, Viral / Q000032:analysis; D001082:Aqueous Humor / Q000821:virology; D003384:Coxsackievirus Infections / Q000175:diagnosis / Q000821:virology*; D004728:Endothelium, Corneal / Q000473:pathology / Q000821:virology*; D030015:Enterovirus C, Human / Q000302:isolation & purification*; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000821:virology*; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007634:Keratitis / Q000175:diagnosis / Q000821:virology*; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D014776:Virus Cultivation; D014792:Visual Acuity
chemical_list: D000956:Antigens, Viral