title: Pd(0)-Catalyzed radical aryldifluoromethylation of activated alkenes.
abstract: A Pd(0)-catalyzed intramolecular aryldifluoromethylation of activated alkenes under mild reaction conditions has been developed. This reaction provides a new method for construction of a variety of difluoromethylated oxindoles. Mechanistic investigations indicate that a difluoromethyl radical, which was triggered by Pd(0), initiated the cascade sequence through an addition to the alkene.
authors.affiliation: Department of Chemistry, University of Technology of China, Hefei 230026, China. xswang77@ustc.edu.cn.
authors.forename: Jian-Yong
authors.initials: JY
authors.lastname: Wang
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Su
authors.forename: Feng
authors.initials: F
authors.lastname: Yin
authors.forename: Yan
authors.initials: Y
authors.lastname: Bao
authors.forename: Xin
authors.initials: X
authors.lastname: Zhang
authors.forename: Yue-Ming
authors.initials: YM
authors.lastname: Xu
authors.forename: Xi-Sheng
authors.initials: XS
authors.lastname: Wang
mesh_terms: D000178:Acrylamides / Q000737:chemistry; D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry; D008745:Methylation; D000078183:Oxindoles; D010165:Palladium / Q000737:chemistry*; D013450:Sulfones / Q000737:chemistry
chemical_list: D000178:Acrylamides; D000475:Alkenes; D006845:Hydrocarbons, Fluorinated; D007211:Indoles; D000078183:Oxindoles; D013450:Sulfones; C022960:2-oxindole; D010165:Palladium