title: [Pulmonary mucormycosis caused by Rhizopus microsporus].
abstract: We report a case of mycotic pneumonia in a patient with acute myeloblastic leukemia. Rhizopus microsporus was identified as an agent of mucormycosis and proven by microscopy and culture. The determination of the isolate was supported by molecular methods. Combined treatment with surgery (right-sided pneumonectomy) and systemic amphotericin B and posaconazole antifungal therapy was chosen. In this case, amphotericin B Neo-Sensitabs tablets gave false "resistant" results on Mueller-Hinton agar when using the disk diffusion test. There was a good correlation between the Etest (16 h) and the Sensititre YeastOne microplate (24 h) for amphotericin B.
authors.affiliation: Laboratory of medical mycology; Department of parasitology, mycology and mycobacteriology Prague; Public Health Institute in Ustí nad Labem, Czech Republic, e-mail: Lyskova.P@seznam.cz.
authors.forename: P
authors.initials: P
authors.lastname: Lysková
authors.forename: P
authors.initials: P
authors.lastname: Žáčková
authors.forename: V
authors.initials: V
authors.lastname: Petečuková
authors.forename: V
authors.initials: V
authors.lastname: Hubka
authors.forename: M
authors.initials: M
authors.lastname: Vašáková
authors.forename: R
authors.initials: R
authors.lastname: Matěj
authors.forename: J
authors.initials: J
authors.lastname: Čermák
authors.forename: A
authors.initials: A
authors.lastname: Kubátová
authors.forename: M
authors.initials: M
authors.lastname: Kolařík
authors.forename: T
authors.initials: T
authors.lastname: Kozák
authors.forename: I
authors.initials: I
authors.lastname: Hricíková
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology / Q000627:therapeutic use; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D009091:Mucormycosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D012233:Rhizopus / Q000187:drug effects / Q000302:isolation & purification
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B