title: Cocirculation of three hemagglutinin and two neuraminidase subtypes of avian influenza viruses in Huzhou, China, April 2013: implication for the origin of the novel H7N9 virus.
abstract: We detected three avian influenza hemagglutinin (HA) subtypes (H7, H9, and H5) and two neuraminidase (NA) subtypes (N9 and N2), as well as H7N9-related H9N9 reassortant intermediates, cocirculating among poultry in Huzhou, China, during April 2013. The results of our study reveal not only that Huzhou is one of the geographic origins of the novel H7N9 virus but also that cocirculation poses a potential threat to humans in the future.
authors.affiliation: Huzhou Center for Disease Control and Prevention, Huzhou, Zhejiang, China.
authors.forename: Jiankang
authors.initials: J
authors.lastname: Han
authors.forename: Lili
authors.initials: L
authors.lastname: Wang
authors.forename: Jia
authors.initials: J
authors.lastname: Liu
authors.forename: Meihua
authors.initials: M
authors.lastname: Jin
authors.forename: Fangyuan
authors.initials: F
authors.lastname: Hao
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
authors.forename: Zhao
authors.initials: Z
authors.lastname: Zhang
authors.forename: Dong
authors.initials: D
authors.lastname: Wen
authors.forename: Xiaofang
authors.initials: X
authors.lastname: Wu
authors.forename: Guangtao
authors.initials: G
authors.lastname: Liu
authors.forename: Lei
authors.initials: L
authors.lastname: Ji
authors.forename: Deshun
authors.initials: D
authors.lastname: Xu
authors.forename: Dongming
authors.initials: D
authors.lastname: Zhou
authors.forename: Qibin
authors.initials: Q
authors.lastname: Leng
authors.forename: Ke
authors.initials: K
authors.lastname: Lan
authors.forename: Chiyu
authors.initials: C
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001499:Bayes Theorem; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D019143:Evolution, Molecular; D006389:Hemagglutinins, Viral / Q000235:genetics*; D006801:Humans; D064766:Influenza A Virus, H7N9 Subtype / Q000235:genetics*; D005585:Influenza in Birds / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D007251:Influenza, Human / Q000453:epidemiology* / Q000821:virology; D009439:Neuraminidase / Q000235:genetics*; D010802:Phylogeny; D011200:Poultry; D060888:Real-Time Polymerase Chain Reaction / Q000662:veterinary; D016865:Reassortant Viruses / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary
chemical_list: D006389:Hemagglutinins, Viral; D009439:Neuraminidase