title: [Lymphoepithelial carcinoma in salivary glands: clinical and pathological analysis of 17 cases].
abstract: OBJECTIVE
  Lymphoepithelial carcinoma (LEC) of salivary glands is a rare malignant neoplasm. The purpose of this research was to investigate the clinicalpathologic features and treatment methods of this rare disease.
  
  
  METHODS
  The clinical data and treatment outcomes of 17 patients from 2006 to 2012 were reviewed retrospectively.
  
  
  RESULTS
  Ten males and seven females with a ratio of 1. 43:1 were involved. The II, III, IV stage cases were 7 (41.2%), 4 (23.5%), 6 (35.3%), respectively. The average follow-up duration was 2.56 years, and 12 patients had no evidence of recurrence. Five patients had local recurrence and (or) distant metastases within three years after surgery, including 4 deaths.
  
  
  CONCLUSIONS
  LEC in salivary gland is a high grade malignant tumor in oral and maxillofacial region, occurring predominately in parotid gland and submandibular gland. To prevent distant metastasis, radical surgery combined with chemoradiotherapy should be adopted.
authors.forename: Xuemin
authors.initials: X
authors.lastname: Yin
authors.forename: Guoxiang
authors.initials: G
authors.lastname: Xu
authors.forename: Leitao
authors.initials: L
authors.lastname: Zhang
authors.forename: Zhifeng
authors.initials: Z
authors.lastname: Chen
authors.forename: Xiao
authors.initials: X
authors.lastname: Liu
authors.forename: Junwei
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018307:Neoplasms, Squamous Cell / Q000473:pathology* / Q000556:secondary; D010307:Parotid Neoplasms / Q000473:pathology; D035583:Rare Diseases / Q000473:pathology*; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000473:pathology*; D012469:Salivary Glands / Q000473:pathology; D013365:Submandibular Gland Neoplasms / Q000473:pathology; D016896:Treatment Outcome