title: The direct effect of specific training and walking on bone metabolic markers in young adults with peak bone mass.
abstract: As a prevention, a physically active lifestyle including the performance of weight-bearing exercises is important to enhance and maintain bone mineral content. Fifty young women were selected for the study. Twenty-five women carried out a specific training directed by a physiotherapist in the training group (TG), while 25 women were walking for 60 minutes in the control group (CG). Total and bone-specific alkaline phosphatase (ALP and BALP) and C-terminal cross-linked telopeptide (CTX) levels were measured at the beginning and at the end of exercise. The most remarkable change was seen in CTX levels (TG -28.89%, p < 0.001; CG -52.54%, p < 0.001), and there was also a significant difference in the values of CTX between TG and CG (p = 0.012). Therefore, walking more significantly reduced the level of CTX than special exercise. The decrease of BALP in TG was considerable but not significant (TG -4.63%, p = 0.091), while BALP levels dropped significantly in CG (-7.65%, p = 0.011), and there was a non-significant difference between the two groups (p = 0.22). Regarding the ALP level, a significant reduction was detected in TG and CG (-6.84%, p < 0.001 vs. -4.57%, p < 0.001). This study reveals that the 60-minute, middle-intensity training and the brisk walking have an immediate effect on bone metabolic markers.
authors.affiliation: University of Pécs Faculty of Health Sciences Zalaegerszeg Hungary Landorhegyi utca 33 H-8900 Zalaegerszeg Hungary.
authors.forename: G
authors.initials: G
authors.lastname: Gombos Császár
authors.affiliation: University of Pécs Faculty of Health Sciences Zalaegerszeg Hungary.
authors.forename: V
authors.initials: V
authors.lastname: Bajsz
authors.affiliation: University of Pécs Faculty of Health Sciences Zalaegerszeg Hungary.
authors.forename: E
authors.initials: E
authors.lastname: Sió
authors.affiliation: University of Pécs Faculty of Health Sciences Zalaegerszeg Hungary.
authors.forename: V
authors.initials: V
authors.lastname: Steinhausz Tóth
authors.affiliation: University of Pécs Faculty of Health Sciences Zalaegerszeg Hungary.
authors.forename: B
authors.initials: B
authors.lastname: Schmidt
authors.affiliation: Hévíz Spa and St. Andrew Rheumatology Hospital Hévíz Hungary.
authors.forename: L
authors.initials: L
authors.lastname: Szekeres
authors.affiliation: University of Pécs Faculty of Health Sciences Pécs Hungary.
authors.forename: J
authors.initials: J
authors.lastname: Kránicz
mesh_terms: D000328:Adult; D000367:Age Factors; D000469:Alkaline Phosphatase / Q000097:blood; D015415:Biomarkers / Q000097:blood; D015519:Bone Density; D016723:Bone Remodeling; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000378:metabolism*; D024042:Collagen Type I / Q000097:blood; D005260:Female; D006801:Humans; D010012:Osteogenesis; D010455:Peptides / Q000097:blood; D055070:Resistance Training; D013997:Time Factors; D014463:Ultrasonography; D016138:Walking; D055815:Young Adult
chemical_list: D015415:Biomarkers; D024042:Collagen Type I; D010455:Peptides; C052929:collagen type I trimeric cross-linked peptide; D000469:Alkaline Phosphatase
keywords: BALP; CTX; body mass density; bone biochemical markers; physical exercise