title: RIG-I inhibits SRC-mediated AKT/mTOR signaling and stemness in AML.
abstract: RIG-I biases myeloid cells toward differentiation and autophagy via suppression of AKT/mTOR.
mesh_terms: D002454:Cell Differentiation; D053487:DEAD-box RNA Helicases / Q000378:metabolism*; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000378:metabolism*; D016392:Proto-Oncogene Proteins pp60(c-src) / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D016392:Proto-Oncogene Proteins pp60(c-src); D053487:DEAD-box RNA Helicases