title: Predictive factors for pelvic magnetic resonance in response to arterial embolization of a uterine leiomyoma.
abstract: OBJECTIVE
  Minimally invasive methods are used as alternatives to treat leiomyomas and include uterine artery embolization, which has emerged as a safe, effective method. This study aims to evaluate the magnetic resonance imaging predictors for a reduction in leiomyoma volume in patients undergoing uterine artery embolization.
  
  
  METHODS
  This prospective longitudinal study was performed at a university hospital. We followed 50 symptomatic premenopausal women with uterine leiomyomas who underwent uterine artery embolization. We examined 179 leiomyomas among these patients. Magnetic resonance imaging was performed one month before and six months after uterine artery embolization. Two radiologists who specialized in abdominal imaging independently interpreted the images.
  
  
  METHODS
  The magnetic resonance imaging parameters were the uterus and leiomyomas volumes, their localizations, contrast perfusion pattern and node-to-muscle ratio.
  
  
  RESULTS
  Six months after treatment, the average uterine volume reduction was 38.91%, and the leiomyomas were reduced by 55.23%. When the leiomyomas were submucosal and/or had a higher node-to-muscle ratio in the T2 images, the volume reduction was even greater (greater than 50%). Other parameters showed no association.
  
  
  CONCLUSIONS
  We conclude that symptomatic uterine leiomyomas in patients undergoing uterine artery embolization exhibit volume reductions greater than 50% by magnetic resonance imaging when the leiomyomas are submucosal and/or had a high node-to-muscle ratio in the T2 images.
authors.affiliation: Hospital Israelita Albert Einstein, Interventional Radiology Department, São PauloSP, Brazil, Hospital Israelita Albert Einstein, Interventional Radiology Department, São Paulo/SP, Brazil.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Zlotnik
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina, Universidade de Universidade de São Paulo, Gynecology Clinic, São PauloSP, Brazil, Hospital das Clínicas da Faculdade de Medicina da Universidade de Universidade de São Paulo, Gynecology Clinic, São Paulo/SP, Brazil.
authors.forename: Marcos de
authors.initials: Md
authors.lastname: Lorenzo Messina
authors.affiliation: Hospital Israelita Albert Einstein, Interventional Radiology Department, São PauloSP, Brazil, Hospital Israelita Albert Einstein, Interventional Radiology Department, São Paulo/SP, Brazil.
authors.forename: Felipe
authors.initials: F
authors.lastname: Nasser
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina, Universidade de Universidade de São Paulo, Gynecology Clinic, São PauloSP, Brazil, Hospital das Clínicas da Faculdade de Medicina da Universidade de Universidade de São Paulo, Gynecology Clinic, São Paulo/SP, Brazil.
authors.forename: Breno Boueri
authors.initials: BB
authors.lastname: Affonso
authors.affiliation: Hospital Israelita Albert Einstein, Interventional Radiology Department, São PauloSP, Brazil, Hospital Israelita Albert Einstein, Interventional Radiology Department, São Paulo/SP, Brazil.
authors.forename: Ronaldo Hueb
authors.initials: RH
authors.lastname: Baroni
authors.affiliation: Hospital Israelita Albert Einstein, Interventional Radiology Department, São PauloSP, Brazil, Hospital Israelita Albert Einstein, Interventional Radiology Department, São Paulo/SP, Brazil.
authors.forename: Nelson
authors.initials: N
authors.lastname: Wolosker
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina, Universidade de Universidade de São Paulo, Gynecology Clinic, São PauloSP, Brazil, Hospital das Clínicas da Faculdade de Medicina da Universidade de Universidade de São Paulo, Gynecology Clinic, São Paulo/SP, Brazil.
authors.forename: Edmund Chada
authors.initials: EC
authors.lastname: Baracat
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000473:pathology / Q000628:therapy*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015999:Multivariate Analysis; D015588:Observer Variation; D010386:Pelvic Neoplasms / Q000473:pathology / Q000628:therapy*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D047368:Tumor Burden; D055357:Uterine Artery Embolization / Q000379:methods*; D014594:Uterine Neoplasms / Q000473:pathology / Q000628:therapy*; D014599:Uterus / Q000098:blood supply / Q000473:pathology