title: Practical synthesis of phthalimides and benzamides by a multicomponent reaction involving arynes, isocyanides, and CO2/H2O.
abstract: Transition-metal-free multicomponent reactions involving arynes and isocyanides with either CO2 or H2O have been reported. With CO2 as the third component, the reactions resulted in the formation of N-substituted phthalimides. The utility of water as the third component furnished benzamide derivatives in moderate to good yields. These reactions took place under mild conditions with broad scope.
authors.affiliation: Organic Chemistry Division, CSIR-National Chemical Laboratory (CSIR-NCL) , Dr. Homi Bhabha Road, Pune - 411008, India.
authors.forename: Trinadh
authors.initials: T
authors.lastname: Kaicharla
authors.forename: Manikandan
authors.initials: M
authors.lastname: Thangaraj
authors.forename: Akkattu T
authors.initials: AT
authors.lastname: Biju
mesh_terms: D000577:Amides / Q000737:chemistry*; D001549:Benzamides / Q000138:chemical synthesis* / Q000737:chemistry; D002245:Carbon Dioxide / Q000737:chemistry*; D003486:Cyanides / Q000737:chemistry*; D015394:Molecular Structure; D010797:Phthalimides / Q000138:chemical synthesis* / Q000737:chemistry; D014867:Water / Q000737:chemistry*
chemical_list: D000577:Amides; D001549:Benzamides; D003486:Cyanides; D010797:Phthalimides; D014867:Water; D002245:Carbon Dioxide