title: Update on the surgical management of Pott's disease.
abstract: One-third of the world's population is infected with Mycobacterium tuberculosis. Data reported in 2011 indicate, for the first time, a decline in cases of tuberculosis, despite persistent inequalities across geographic areas and increasing rates of drug resistance. Osteo-articular tuberculosis affects the spine in half the cases. Pharmacotherapy must be combined with surgery in patients with spinal cord or nerve root compression, large abscesses, or marked anterior column osteolysis with kyphosis and instability. The quality of debridement and bony fusion is optimal when the anterior approach is used. Posterior fixation is the best means of achieving reduction followed by stable sagittal alignment over time. New treatment strategies combine conventional surgical methods, closed interventional radiology procedures for drainage and spinal cord decompression, and percutaneous fixation.
authors.affiliation: Service de chirurgie du rachis, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France; Fédération de médecine translationnelle (FMTS), université de Strasbourg, 4, rue Blaise-Pascal, 67400 Strasbourg, France.
authors.forename: S
authors.initials: S
authors.lastname: Varatharajah
authors.affiliation: Service de chirurgie du rachis, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France; Fédération de médecine translationnelle (FMTS), université de Strasbourg, 4, rue Blaise-Pascal, 67400 Strasbourg, France. Electronic address: yann.philippe.charles@chru-strasbourg.fr.
authors.forename: Y-P
authors.initials: YP
authors.lastname: Charles
authors.affiliation: Service de radiologie interventionnelle, hôpitaux universitaires de Strasbourg, hopitaux universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France; Fédération de médecine translationnelle (FMTS), université de Strasbourg, 4, rue Blaise-Pascal, 67400 Strasbourg, France.
authors.forename: X
authors.initials: X
authors.lastname: Buy
authors.affiliation: Service de chirurgie du rachis, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France; Fédération de médecine translationnelle (FMTS), université de Strasbourg, 4, rue Blaise-Pascal, 67400 Strasbourg, France.
authors.forename: A
authors.initials: A
authors.lastname: Walter
authors.affiliation: Service de chirurgie du rachis, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France; Fédération de médecine translationnelle (FMTS), université de Strasbourg, 4, rue Blaise-Pascal, 67400 Strasbourg, France.
authors.forename: J-P
authors.initials: JP
authors.lastname: Steib
mesh_terms: D000038:Abscess / Q000209:etiology / Q000601:surgery; D000995:Antitubercular Agents / Q000627:therapeutic use; D003646:Debridement; D019299:Decompression, Surgical; D004322:Drainage; D006801:Humans; D007738:Kyphosis / Q000209:etiology / Q000517:prevention & control / Q000601:surgery; D019637:Orthopedic Procedures; D011843:Radiculopathy / Q000209:etiology / Q000601:surgery; D013117:Spinal Cord Compression / Q000209:etiology / Q000601:surgery; D014399:Tuberculosis, Spinal / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*
chemical_list: D000995:Antitubercular Agents
keywords: Abscess; Kyphosis; Pott's disease; Spinal tuberculosis; Spondylitis; Surgical treatment