title: Vanishing hypercalciuric kidney stones after treating underlying acromegaly.
abstract: A 53-year-old male presented with recurrent calcium oxalate kidney stones as a first sign of underlying acromegaly, which vanished when his acromegaly was controlled. The exact mechanism behind hypercalciuria and urolithiasis in acromegaly is not yet clear. By discussing this case, a short overview of the pathophysiology of hypercalciuria in acromegaly and practical insights are given.
  
  
  CONCLUSIONS
  Hypercalciuria is a common finding in acromegaly.There are only few reports describing hypercalciuric kidney stones in acromegaly.We assume that in acromegaly there is a primary role of IGF1-mediated, PTH-independent increase in calcitriol synthesis resulting in hypercalciuric kidney stones.
authors.affiliation: Diakonessenhuis Utrecht, Department of Internal Medicine Postbus 80250, 3508 TG, Utrecht The Netherlands.
authors.forename: Eline
authors.initials: E
authors.lastname: van der Valk
authors.affiliation: Diakonessenhuis Utrecht, Department of Internal Medicine Postbus 80250, 3508 TG, Utrecht The Netherlands.
authors.forename: Tom
authors.initials: T
authors.lastname: Tobe
authors.affiliation: UMC Utrecht, Department of Endocrinology Postbus 85500, 3508 GA, Utrecht The Netherlands.
authors.forename: Aline
authors.initials: A
authors.lastname: Stades
authors.affiliation: Diakonessenhuis Utrecht, Department of Internal Medicine Postbus 80250, 3508 TG, Utrecht The Netherlands.
authors.forename: Alex
authors.initials: A
authors.lastname: Muller