title: A novel hybrid metal-organic framework-polymeric monolith for solid-phase microextraction.
abstract: This study describes the fabrication of a novel hybrid metal-organic framework- organic polymer (MOF-polymer) for use as a stationary phase in fritless solid-phase microextraction (SPME) for validating analytical methods. The MOF-polymer was prepared by using ethylene dimethacrylate (EDMA), butyl methacrylate (BMA), and an imidazolium-based ionic liquid as porogenic solvent followed by microwave-assisted polymerization with the addition of 25 % MOF. This novel hybrid MOF-polymer was used to extract penicillin (penicillin G, penicillin V, oxacillin, cloxacillin, nafcillin, dicloxacillin) under different conditions. Quantitative analysis of the extracted penicillin samples using the MOF-organic polymer for SPME was conducted by using capillary electrochromatography (CEC) coupled with UV analysis. The penicillin recovery was 63-96.2 % with high reproducibility, sensitivity, and reusability. The extraction time with the proposed fabricated SPME was only 34 min.
authors.affiliation: Department of Chemistry, Chung Yuan Christian University, 200 Chung Pei Road, Chung-Li, 320 (Taiwan).
authors.forename: Chen-Lan
authors.initials: CL
authors.lastname: Lin
authors.forename: Stephen
authors.initials: S
authors.lastname: Lirio
authors.forename: Ya-Ting
authors.initials: YT
authors.lastname: Chen
authors.forename: Chia-Her
authors.initials: CH
authors.lastname: Lin
authors.forename: Hsi-Ya
authors.initials: HY
authors.lastname: Huang
keywords: capillary electrochromatography; metal-organic frameworks; penicillin; polymers; solid-phase microextraction