title: Therapeutic effect of adipose-derived mesenchymal stem cell injection in horses suffering from bone spavin.
abstract: In this article we demonstrate the efficiency of autologous transplantations of adipose-derived mesenchymal stem cells for equine bone spavin treatment. Horses qualified to the study were divided into three groups: (i) research - treated with intra-articular injections of autologous stem cells, (ii) comparison treated with steroid drugs and (iii) control - untreated. All animals underwent comprehensive clinical examination before and after treatment. Our research confirms the long-term beneficial influence resulting from stem cell therapy in horse bone spavin treatment, in contrast to routine steroid usage.
authors.affiliation: Department of Surgery, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, pl. Grunwaldzki 51, 50-366 Wroclaw, Poland. nickub@poczta.onet.pl
authors.forename: J
authors.initials: J
authors.lastname: Nicpoń
authors.affiliation: Electron Microscopy Laboratory, University of Environmental and Life Sciences, Kozuchowska 5b, 50-375 Wroclaw, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Marycz
authors.affiliation: Electron Microscopy Laboratory, University of Environmental and Life Sciences, Kozuchowska 5b, 50-375 Wroclaw, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Grzesiak
mesh_terms: D000273:Adipose Tissue / Q000166:cytology*; D000818:Animals; D001623:Betamethasone / Q000008:administration & dosage / Q000627:therapeutic use*; D006734:Horse Diseases / Q000628:therapy*; D006736:Horses; D007249:Inflammation / Q000628:therapy / Q000662:veterinary*; D007592:Joint Diseases / Q000662:veterinary*; D007794:Lameness, Animal; D059630:Mesenchymal Stem Cells / Q000502:physiology*
chemical_list: D001623:Betamethasone