title: Tumor differentiation as related to sentinel lymph node status in gastric cancer.
abstract: OBJECTIVE
  To investigate the influence of tumor grade on sentinel lymph node (SLN) status in patients with gastric cancer (GC).
  
  
  METHODS
  We retrospectively studied 71 patients with GC who underwent SLN mapping during gastric surgery to evaluate the relationship between SLN status and tumor grade.
  
  
  RESULTS
  Poorly differentiated tumors were detected in 50/71 patients, while the other 21 patients had moderately differentiated tumors. SLNs were identified in 58/71 patients (82%). In 41 of the 58 patients that were found to have stained nodes (70.7%), the tumor was of the poorly differentiated type (group I), while in the remaining patients with stained nodes 17/58 (29.3%), the tumor was of the moderately differentiated type (group II). Positive SLNs were found in 22/41 patients in group I (53.7%) and in 7/17 patients in group II (41.2%) (P = 0.325). The rate of positivity for the SLNs in the two groups (53.7% vs 41.2%) was not statistically significant (P = 0.514).
  
  
  CONCLUSIONS
  Most of our patients were found to have poorly differentiated adenocarcinoma of the stomach and there was no correlation between tumor grade and SLN involvement.
authors.affiliation: Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Ariel Halevy, Division of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel.
authors.forename: Ron
authors.initials: R
authors.lastname: Lavy
authors.affiliation: Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Ariel Halevy, Division of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel.
authors.forename: Andronik
authors.initials: A
authors.lastname: Kapiev
authors.affiliation: Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Ariel Halevy, Division of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel.
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Hershkovitz
authors.affiliation: Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Ariel Halevy, Division of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel.
authors.forename: Natan
authors.initials: N
authors.lastname: Poluksht
authors.affiliation: Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Ariel Halevy, Division of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel.
authors.forename: Igor
authors.initials: I
authors.lastname: Rabin
authors.affiliation: Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Ariel Halevy, Division of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel.
authors.forename: Bar
authors.initials: B
authors.lastname: Chikman
authors.affiliation: Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Ariel Halevy, Division of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel.
authors.forename: Zahar
authors.initials: Z
authors.lastname: Shapira
authors.affiliation: Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Ariel Halevy, Division of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel.
authors.forename: Ilan
authors.initials: I
authors.lastname: Wasserman
authors.affiliation: Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Ariel Halevy, Division of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel.
authors.forename: Judith
authors.initials: J
authors.lastname: Sandbank
authors.affiliation: Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Ariel Halevy, Division of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel.
authors.forename: Ariel
authors.initials: A
authors.lastname: Halevy
keywords: Gastric cancer; Prognosis; Sentinel lymph node mapping; Sentinel lymph nodes; Tumor differentiation