title: Adverse Histopathology and Imaging Findings in Reduction Mammaplasty Day-surgery Patients.
abstract: OBJECTIVE
  Reduction mammaplasty is a popular procedure in plastic surgery. Occasionally, occult invasive breast carcinoma or findings demonstrating increased risk of breast cancer occur in reduction mammaplasty specimens. The incidences have been studied elsewhere, but in Finland, the data on this subject are lacking. Our aim was to analyze the incidence of occult invasive and in situ carcinoma and benign breast disease causing increased risk of breast cancer in reduction mammaplasty specimens. We also analyzed preoperative mammograms and ultrasound images and compared findings with reduction mammaplasty specimens.
  
  
  METHODS
  We performed a retrospective study of 100 women who underwent reduction mammaplasty during 1 January 2007 to 30 April 2009 in Jorvi Hospital day-surgery unit. Demographic data, findings in preoperative imaging, pathology reports, postoperative follow-up, and retrospective reanalysis of preoperative imaging were recorded.
  
  
  RESULTS
  Histological abnormality occurred in 14.6% of the patients. In situ carcinoma was diagnosed in 4.5% of the patients, and findings demonstrating increased risk of breast cancer were diagnosed in 13.5% of the patients. More than one lesion demonstrating increased risk of breast cancer was diagnosed in 4.5% of the patients. No invasive carcinoma occurred. Preoperative mammogram was performed for the majority (94.0%) of the patients.
  
  
  CONCLUSIONS
  We detected a considerable amount of findings in reduction mammaplasty specimens with prognostic value with regard to future breast cancer risk. We recommend histological analysis for reduction mammaplasty specimens and focus attention on systematically performed preoperative imaging.
authors.affiliation: Department of Plastic Surgery, Helsinki University Central Hospital, Helsinki, Finland paivi.merkkola-vonschantz@hus.fi.
authors.forename: P
authors.initials: P
authors.lastname: Merkkola-von Schantz
authors.affiliation: Department of Plastic Surgery, Helsinki University Central Hospital, Helsinki, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Jahkola
authors.affiliation: Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland Department of Surgery, University of Turku, Turku, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Carpelan
authors.affiliation: Department of Pathology, Helsinki University Central Hospital, Helsinki, Finland.
authors.forename: L
authors.initials: L
authors.lastname: Krogerus
authors.affiliation: Department of Radiology, Helsinki University Central Hospital, Helsinki, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Hukkinen
authors.affiliation: Department of Plastic Surgery, Helsinki University Central Hospital, Helsinki, Finland.
authors.forename: S
authors.initials: S
authors.lastname: Kauhanen
keywords: Reduction mammaplasty; benign breast disease; breast cancer; breast cancer risk; histopathology; occult cancer; preoperative imaging