title: Vitamin K and bone health in older adults.
abstract: Vitamin K is one of several nutrients that have been linked with bone health. In particular, there is an emerging literature regarding the questionable efficacy of vitamin K supplementation in reducing age-related bone loss. This review aims to summarize the role of vitamin K in bone health in older adults and discuss the clinical implications from a select few human studies. The evidence for vitamin K supplementation in older adults is mixed. Although the observational studies have shown linkages between vitamin K intake and lower risk of fractures in this population, the current evidence from randomized controlled trials is not strongly supportive of vitamin K supplementation in older adults for the intent of improving bone health.
authors.affiliation: a Division of Geriatrics and Aging , University of Rochester School of Medicine and Dentistry , Rochester , New York , USA.
authors.forename: Krupa
authors.initials: K
authors.lastname: Shah
authors.forename: Lauren
authors.initials: L
authors.lastname: Gleason
authors.forename: Dennis T
authors.initials: DT
authors.lastname: Villareal
mesh_terms: D000375:Aging; D001842:Bone and Bones / Q000378:metabolism*; D004032:Diet / Q000009:adverse effects; D019587:Dietary Supplements; D019317:Evidence-Based Medicine; D006293:Health Promotion; D006801:Humans; D018673:Nutrition Policy; D010024:Osteoporosis / Q000209:etiology / Q000517:prevention & control*; D015203:Reproducibility of Results; D014812:Vitamin K / Q000378:metabolism / Q000627:therapeutic use*; D014813:Vitamin K Deficiency / Q000178:diet therapy* / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control
chemical_list: D014812:Vitamin K