title: Supporting prostate cancer focal therapy: a multidisciplinary International Consensus of Experts ("ICE").
abstract: Prostate cancer is a common malignancy among men, and the current screening, imaging and sampling approaches aim to detect early-stage, organ-confined disease. In such scenario, focal prostate cancer therapy currently relies on the index lesion concept as the dominant lesion that drives the disease natural history. Focal therapy demands the essential imaging and sampling techniques to strategically locate and qualify the disease, but, despite advances in technology, prostate imaging and biopsy have several limitations that need to be overcome if focal therapy is to be developed further. The I Prostate Cancer Focal Treatment International Symposium was convened to foster discussion on this topic that sits at the crossroads of multiple disciplines (Urology, Pathology, Radiology, Radiation Oncology and Medical Oncology) all of which were represented for this comprehensive multidisciplinary review of the current literature.
authors.affiliation: Department of Urology and Pathology, University of Campinas, UNICAMP , Campinas, São Paulo , Brazil .
authors.forename: Leonardo O
authors.initials: LO
authors.lastname: Reis
authors.forename: Athanase
authors.initials: A
authors.lastname: Billis
authors.forename: Stenio C
authors.initials: SC
authors.lastname: Zequi
authors.forename: Marcos
authors.initials: M
authors.lastname: Tobias-Machado
authors.forename: Publio
authors.initials: P
authors.lastname: Viana
authors.forename: Michael
authors.initials: M
authors.lastname: Cerqueira
authors.forename: John F
authors.initials: JF
authors.lastname: Ward
mesh_terms: D001706:Biopsy; D032921:Consensus; D019468:Disease Management; D006801:Humans; D033183:Interdisciplinary Communication; D008279:Magnetic Resonance Imaging; D008297:Male; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology / Q000628:therapy*
keywords: Ablation techniques; HIFU; MRI; cryoablation; focal therapy; index lesion; prostatic neoplasms; transrectal ultrasound