title: Histoplasmosis mimicking adrenal carcinoma.
abstract: OBJECTIVE
  The incidence of unilateral adrenal histoplasmosis in nonendemic areas is rare. This is even rarer if the host is immunocompetent.
  
  
  METHODS
  We report a patient who was referred for unexplained weight loss who underwent a computed tomography scan of abdomen revealing a large unilateral adrenal nodule measuring 7.6 cm in size.
  
  
  RESULTS
  Hormonal workup was negative including urine 24-hour free metanephrines, and the patient underwent unilateral adrenalectomy. The pathology showed budding yeast that stained with Gomori's methenamine silver (GMS) revealed the diagnosis of adrenal histoplasmosis.
  
  
  CONCLUSIONS
  We encourage clinicians to include infection by Histoplasma capsulatum as well as other granulomatous diseases and tumors in the differential diagnosis of unilateral adrenal enlargement even in immunocompetent hosts living in nonendemic areas.
authors.affiliation: Division of Endocrinology, Department of Internal Medicine, Baylor Scott & Whit e Health/Texas A&M Health Science Center College of Medicine, Temple, Texas, USA. drrajashree.pai@gmail.com
authors.forename: Rajasreepai Ramachandra
authors.initials: RR
authors.lastname: Pai
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Baylor Scott & White Health/Texas A&M Health Science Center College of Medicine, Temple, Texas, USA.
authors.forename: Raghesh Varot
authors.initials: RV
authors.lastname: Kangath
authors.affiliation: Division Endocrinology and Metabolism, Central Texas Veteran's Health Care System, Temple, Texas, USA.
authors.forename: Immanuel
authors.initials: I
authors.lastname: Thamban
mesh_terms: D000307:Adrenal Gland Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006660:Histoplasmosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged