title: [A case report of hepatocellular carcinoma with metastases to the lip, stomach, and colorectum].
abstract: A 79-year-old man was diagnosed with hepatocellular carcinoma in 2000 and treated with partial hepatectomy. Intrahepatic carcinoma recurred with lung metastases 7 years later. Several transcatheter arterial chemoembolizations were performed to treat the recurrence, and a right lower lobectomy was performed for lung metastasis. Twelve years after the original carcinoma diagnosis, lip and lung metastases were detected, and he was hospitalized for radiotherapy of the lung metastasis; an oral molecular-targeting drug was initiated. During the therapy, hematochezia was observed, and a colonoscopy was performed. A submucosal lesion with a blood clot measuring approximately 4mm in diameter was found in the sigmoid colon, and endoscopic mucosal resection was performed. Furthermore, an elevated lesion with a 5-mm diameter recess was observed on upper gastrointestinal endoscopy. Both lesions were diagnosed histopathologically as hepatocellular carcinoma metastases.
authors.affiliation: Department of Gastroenterology, Hiroshima City Asa Hospital.
authors.forename: Eisuke
authors.initials: E
authors.lastname: Miyaki
authors.forename: Koji
authors.initials: K
authors.lastname: Waki
authors.forename: Keiji
authors.initials: K
authors.lastname: Tsuji
authors.forename: Yuhei
authors.initials: Y
authors.lastname: Saito
authors.forename: Daiki
authors.initials: D
authors.lastname: Hirano
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Tamaru
authors.forename: Masahiro
authors.initials: M
authors.lastname: Hatooka
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Takata
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ueda
authors.forename: Kenichi
authors.initials: K
authors.lastname: Kuwahara
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kimura
authors.forename: Shinji
authors.initials: S
authors.lastname: Nagata
authors.forename: Mayumi
authors.initials: M
authors.lastname: Kaneko
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Aikata
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Chayama
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D015179:Colorectal Neoplasms / Q000556:secondary*; D006801:Humans; D008048:Lip Neoplasms / Q000556:secondary*; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D013274:Stomach Neoplasms / Q000556:secondary*