title: Palladium-catalyzed intramolecular asymmetric C-H functionalization/cyclization reaction of metallocenes: an efficient approach toward the synthesis of planar chiral metallocene compounds.
abstract: A palladium-catalyzed asymmetric synthesis of planar chiral metallocene compounds is reported. The reaction stereoselectively functionalized one of the ortho C-H bonds of Cp rings by intramolecular cyclization to form indenone derivatives in high yields with excellent enantioselectivity. The mild set of reaction conditions allowed a wide variety of chiral metallocene compounds to be synthesized with broad functional group tolerance. The influences of preinstalled chiralities on the other Cp-ring were also investigated.
authors.affiliation: Department of Chemistry, University of Science and Technology of China , 96 Jinzhai Road, Hefei, Anhui 230026, China.
authors.forename: Ruixian
authors.initials: R
authors.lastname: Deng
authors.forename: Yunze
authors.initials: Y
authors.lastname: Huang
authors.forename: Xinna
authors.initials: X
authors.lastname: Ma
authors.forename: Gencheng
authors.initials: G
authors.lastname: Li
authors.forename: Rui
authors.initials: R
authors.lastname: Zhu
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
authors.forename: Yan-Biao
authors.initials: YB
authors.lastname: Kang
authors.forename: Zhenhua
authors.initials: Z
authors.lastname: Gu