title: Quality of life and the risk of contracting malaria by multivariate analysis in the Brazilian Amazon region.
abstract: BACKGROUND
  The incidence of malaria in the Amazon basin is closely related to social inequalities, given that precarious economic and socio-environmental conditions represent favourable factors for the transmission of the disease in tropical regions, such as the Brazilian state of Pará. In the present study, an association was found between the variation in a quality of life index (QLI), based on the socioeconomic differences between the municipalities of this state, and the risk of contracting malaria, based on the Annual Parasitic Index (API), with the primary objective of providing guidelines for the development of effective strategies for the control of the disease.
  
  
  METHODS
  The API scores for the years between 2003 and 2011 were collected from the Brazilian Ministry of Health's DATASUS database, and socioeconomic data for the 143 municipalities of Pará were obtained from the 2010 census. The data were analysed using multivariate factorial and correspondence techniques.
  
  
  RESULTS
  The QLI was calculated for each municipality, of which, 69.23% were classified as having a poor or regular quality of life. The municipalities with poor QLI scores also presented moderate to high rates of malaria, with probabilities of 80.97% and 95.13%, respectively, while those with good QLI scores had low rates of malaria, with a probability of 79.24%. The results indicated a concentration of malaria in the south-west of the state of Pará, with an increase of 8.82% in the incidence of the disease over the study period, and the northeastern and Marajó mesoregions, where there was an increase of over 90%. In south-eastern Pará, by contrast, there was a marked reduction (78%) in the incidence of the disease, reflecting the heterogeneous distribution of malaria among the different municipalities and mesoregions of the state, especially those with moderate to high risk of transmission.
  
  
  CONCLUSIONS
  These findings confirm that malaria is endemic to Pará and is typical of the state's poorest areas, and that the distribution of the disease within the state indicates an intimate relationship with the living conditions of the population, affecting primarily the economically less privileged sectors of the society.
authors.forename: Sergio G L
authors.initials: SG
authors.lastname: Junior
authors.affiliation: Universidade Federal Rural da Amazônia, Rodovia PA 256, Km 6, S/N, Nova Conquista, CEP 68625-970 Paragominas, Pará, Brazil. vanessamayara2@gmail.com.
authors.forename: Vanessa M S
authors.initials: VM
authors.lastname: Pamplona
authors.forename: Tereza C O
authors.initials: TC
authors.lastname: Corvelo
authors.forename: Edson M L S
authors.initials: EM
authors.lastname: Ramos
mesh_terms: D001938:Brazil / Q000453:epidemiology; D019353:Endemic Diseases; D006801:Humans; D008288:Malaria / Q000453:epidemiology* / Q000635:transmission; D015999:Multivariate Analysis; D011788:Quality of Life; D018570:Risk Assessment; D012959:Socioeconomic Factors