title: Fatty infiltration of the shoulder: diagnosis and reversibility.
abstract: Fatty degeneration is a degenerative condition of the tendon-muscle unit of rotator cuff muscles, characterized by atrophy of muscle fibers, fibrosis, and fatty accumulation within and around the muscles. Many classification may be useful to stage this pathology, especially on Computed Tomography (CT) and magnetic resonance imaging (Mari) findings. Stem cell-based therapies for repair and regeneration of tendons and muscles may be used to promote healing and to make this condition reversible. Diagnosis and management of this condition is mandatory as in patients undergoing rotator cuff repair, it may influence outcomes, increase the likelihood of re-tearing, and evolve negatively.
authors.affiliation: Unit of Arthroscopic and Sports Medicine, Hesperia Hospital, Modena, Italy.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Osti
authors.affiliation: Unit of Orthopaedics and Traumatology, University of Ferrara, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Buda
authors.affiliation: Department of Orthopaedic and Trauma Surgery Hospital Antonio Cardarelli, Campobasso, Italy.
authors.forename: Angelo
authors.initials: A
authors.lastname: Del Buono
keywords: diagnosis; fatty degeneration; management; outcomes