title: Seroprevalence rates of hepatitis C virus (HCV) antibody and hepatitis B virus surface antigen (HBsAG) in blood donors in a Southwestern Nigerian city.
abstract: Hepatitis B and C have been identified as major causes of Transfusion transmitted infections, in Nigeria. Our objective was to determine the prevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) in prospective blood donors in Abeokuta, Nigeria. 305 blood donors were screened for the presence of Hepatitis B virus surface antigen (HBsAg) and HCV using a rapid immunochromatographic kit (DiaSpot®). Demographic information was also collected. Males constituted 96.4%, singles were the majority with 65%. Prevalence of HBsAg was 9.8%, HCV 1.3%, and dual positivity 0.3%. Prevalence of HBsAg and HCV among males was 10.2% and 1.4%, while females recorded 0.0% for HCV and HBsAg. Dual positivity was recorded in a male (0.33%). Analysis of the study variables revealed that only educational status was statistically associated with positivity of HBsAg [Formula: see text], HCV prevalence was highest in the illiterate group it was not statistically significant (P > 0.05). We report the prevalence rates of anti-HCV Ab and HBsAg in blood donors from Ogun State, Nigeria. Our results reveals higher rate of HBsAg and evidence of co-infection with both viruses, illiteracy was the only variable associated with HBV infection. We advocate for the inclusion of anti-HBc or HBeAg in donor screening in our environment.
authors.affiliation: a Microbiology Unit , Pathology Department, Federal Medical Centre , Abeokuta , Nigeria.
authors.forename: Babatunde O
authors.initials: BO
authors.lastname: Motayo
authors.forename: Onoja M
authors.initials: OM
authors.lastname: Akpa
authors.forename: Isreal
authors.initials: I
authors.lastname: Ezeani
authors.forename: Adedayo O
authors.initials: AO
authors.lastname: Faneye
authors.forename: Usen A
authors.initials: UA
authors.lastname: Udo
authors.forename: Bernard
authors.initials: B
authors.lastname: Onoja
mesh_terms: D003430:Cross-Sectional Studies; D005260:Female; D006514:Hepatitis B Surface Antigens / Q000097:blood* / Q000276:immunology; D018937:Hepatitis C Antibodies / Q000097:blood* / Q000276:immunology; D006801:Humans; D008297:Male; D009549:Nigeria / Q000453:epidemiology; D011446:Prospective Studies; D016036:Seroepidemiologic Studies
chemical_list: D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies
keywords: HBsAg; HCV; abeokuta; blood donors; seoprevailence