title: Hollow-fiber-supported liquid-phase microextraction using an ionic liquid as the extractant for the pre-concentration of bisphenol A, 17-β-estradiol, estrone and diethylstilbestrol from water samples with HPLC detection.
abstract: A new method for the determination of four endocrine disrupting compounds (EDCs) (bisphenol A, 17-β-estradiol, estrone and diethylstilbestrol) in water samples has been developed using polypropylene hollow-fiber-supported ionic liquid (IL, 1-Octyl-3-methylimidazolium hexafluorophosphate, [C8MIM][PF6]) microextraction [HF-liquid-phase microextraction (LPME)] combined with high-performance liquid chromatography (HPLC)/UV. This method was used to investigate pollutants in surface water, on the Neijiang River, located at Zhenjiang, Jiangsu Province. Several parameters (sample pH, volume of accepter phase, ionic strength) were investigated. Under the optimum extraction conditions (sample pH, 2.0; volume of extraction solvent, 2.5 μL; ionic strength, 2.57) the proposed method offered: good linearity range, 0.15-100 μg L(-1), with the correlation coefficients (r(2)) of 0.9996, 0.9994, 0.9990 and 0.9984, respectively; low limits of detection, 0.03, 0.05, 0.10, 0.05 μg L(-1) (S/N = 3) for bisphenol A, 17-β-estradiol, estrone and diethylstilbestrol, respectively; good reproducibility (relative standard deviation (RSD), 8.41, 7.61, 9.00, 7.22%, respectively, n = 5); satisfactory recoveries (80.2-107.1%, n = 5); and high enrichment factors, 5,240, 3,693, 2,425 and 2,086, were achieved, for the four chemicals, respectively. Using the proposed HF-LPME, among 15 sampling sites along Neijiang River, bisphenol A, diethylstilbestrol and 17-β-estradiol were detected in some sites, all of which were the near suburban sampling sites. The results indicate that the role of municipal sewage is an important source of EDC contamination.
authors.affiliation: School of Pharmacy, Jiangsu University, 301 Xuefu Rd., 212013 Zhenjiang, Jiangsu, China.
authors.forename: Yanmin
authors.initials: Y
authors.lastname: Zou
authors.affiliation: School of the Environment, Jiangsu University, 301 Xuefu Rd., 212013 Zhenjiang, Jiangsu, China E-mail: zhangzhen@ujs.edu.cn.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: School of the Environment, Jiangsu University, 301 Xuefu Rd., 212013 Zhenjiang, Jiangsu, China E-mail: zhangzhen@ujs.edu.cn.
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Shao
authors.affiliation: School of the Environment, Jiangsu University, 301 Xuefu Rd., 212013 Zhenjiang, Jiangsu, China E-mail: zhangzhen@ujs.edu.cn.
authors.forename: Yao
authors.initials: Y
authors.lastname: Chen
authors.affiliation: School of the Environment, Jiangsu University, 301 Xuefu Rd., 212013 Zhenjiang, Jiangsu, China E-mail: zhangzhen@ujs.edu.cn.
authors.forename: Xiangyang
authors.initials: X
authors.lastname: Wu
authors.affiliation: School of Chemistry & Chemical Engineering, Jiangsu University, 301 Xuefu Rd., 212013 Zhenjiang, Jiangsu, China E-mail: yangliuqing@ujs.edu.cn.
authors.forename: Liuqing
authors.initials: L
authors.lastname: Yang
authors.affiliation: School of the Environment, Jiangsu University, 301 Xuefu Rd., 212013 Zhenjiang, Jiangsu, China E-mail: zhangzhen@ujs.edu.cn.
authors.forename: Jingjing
authors.initials: J
authors.lastname: Zhu
authors.affiliation: School of the Environment, Jiangsu University, 301 Xuefu Rd., 212013 Zhenjiang, Jiangsu, China E-mail: zhangzhen@ujs.edu.cn.
authors.forename: Dongmei
authors.initials: D
authors.lastname: Zhang
mesh_terms: D001559:Benzhydryl Compounds / Q000032:analysis*; D001881:Borates / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004054:Diethylstilbestrol / Q000032:analysis*; D052244:Endocrine Disruptors / Q000032:analysis*; D004784:Environmental Monitoring; D004958:Estradiol / Q000032:analysis*; D004970:Estrone / Q000032:analysis*; D006812:Humic Substances; D007093:Imidazoles / Q000737:chemistry*; D052578:Ionic Liquids / Q000737:chemistry; D059627:Liquid Phase Microextraction / Q000379:methods*; D009994:Osmolar Concentration; D010636:Phenols / Q000032:analysis*; D045483:Rivers / Q000737:chemistry; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D001881:Borates; D004054:Diethylstilbestrol; D052244:Endocrine Disruptors; D004958:Estradiol; D004970:Estrone; D006812:Humic Substances; D007093:Imidazoles; D052578:Ionic Liquids; D010636:Phenols; C528768:1-octyl-3-methylimidazolium; C006780:bisphenol A; D000098826:Bisphenol A Compounds