title: Application of traditional Chinese medicine preparation in targeting drug delivery system.
abstract: Targeting drug system (TDS) or targeted drug delivery system (TDDS) is a new kind of drug delivery system which could make drug to be directly concentrated on the target site with high curative effects and low side-effects. As the quintessence of Chinese culture, traditional Chinese medicine (TCM) has a large advantage in many disease clinical treatments, especially in cancer, hypertension and many other intractable diseases owing to their low toxicity and side-effects relative to western medicine. This article reviews literatures on development of TCM-targeted preparations which were published in the past 10 years. TDS including active-targeting, passive-targeting and physical-chemical-targeting preparations were introduced through domestic and overseas literatures to reveal the unique advantages of TCM-targeting preparations in drug delivery system. In this article, we have reviewed some kinds of TCM-targeting preparations and indicated that great attention should be paid to the research on the TCM-targeting preparations.
authors.affiliation: School of Pharmacy, Health Science Center, Xi' an Jiaotong University , Xi'an , China.
authors.forename: Wei
authors.initials: W
authors.lastname: Xu
authors.forename: Feng J
authors.initials: FJ
authors.lastname: Xing
authors.forename: Kai
authors.initials: K
authors.lastname: Dong
authors.forename: Cuiyu
authors.initials: C
authors.lastname: You
authors.forename: Yan
authors.initials: Y
authors.lastname: Yan
authors.forename: Lu
authors.initials: L
authors.lastname: Zhang
authors.forename: Guilan
authors.initials: G
authors.lastname: Zhao
authors.forename: Youliang
authors.initials: Y
authors.lastname: Chen
authors.forename: Ke
authors.initials: K
authors.lastname: Wang
mesh_terms: D001692:Biological Transport; D004337:Drug Carriers / Q000737:chemistry; D016503:Drug Delivery Systems / Q000379:methods* / Q000639:trends; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D004655:Emulsions; D006801:Humans; D008081:Liposomes; D008863:Microspheres; D053758:Nanoparticles; D010316:Particle Size; D013499:Surface Properties
chemical_list: D004337:Drug Carriers; D004365:Drugs, Chinese Herbal; D004655:Emulsions; D008081:Liposomes
keywords: Clinical treatments; TCM-targeted preparations; pharmacological effects; targeting drug delivery system; traditional Chinese medicine