title: Severe vitamin B12 deficiency with pancytopenia, hepatosplenomegaly and leukoerythroblastosis in two Syrian refugee infants: a challenge to differentiate from acute leukaemia.
abstract: Megaloblastic anaemia due to vitamin B12 deficiency is rare in childhood. However, as most cases are due to maternal insufficiency, it is mainly seen in breastfed infants especially when the mother's socioeconomic status is low and the nutrition is not adequate. We present case of two Syrian refugee infants with severe vitamin B12 deficiency with pancytopenia, hepatosplenomegaly and leukoerythroblastosis.
authors.affiliation: Department of Pediatric Hematology and Oncology, Gaziantep Childrens' Hospital, Gaziantep, Turkey.
authors.forename: Burcu
authors.initials: B
authors.lastname: Belen
authors.forename: Burcu Ozturk
authors.initials: BO
authors.lastname: Hismi
authors.forename: Ulker
authors.initials: U
authors.lastname: Kocak
mesh_terms: D000750:Anemia, Myelophthisic / Q000175:diagnosis / Q000209:etiology*; D000752:Anemia, Pernicious / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006529:Hepatomegaly / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007223:Infant; D008297:Male; D010198:Pancytopenia / Q000175:diagnosis / Q000209:etiology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis*; D012036:Refugees; D013163:Splenomegaly / Q000175:diagnosis / Q000209:etiology*; D013593:Syria; D014421:Turkey