title: Role of taxanes in the treatment of advanced NHL patients: A randomized study of 87 cases.
abstract: NHL is a highly chemo-sensitive as well as radiosensitive disease. From May 2005 to June 2010, 87 patients were randomised into 2 arms. The control arm received the standard CHOP regimen + IFRT, whereas the study arm received Paclitaxel, 135/m2 additionally. The results showed a better Overall Response (87% vs 78%) in the study arm. The 3yr and 5yr overall survival were significantly better in the study arm (89% vs 77%, p- value <0.05; 83% vs 67%, p-value <0.05). However, the incidence and severity of the side effects, haematological and non- haematological were enhanced but manageable in the study arm.
  
  
  BACKGROUND
  Taxanes, Paclitaxel, Non Hodgkin's Lymphoma.
authors.affiliation: Professor Shraddha Raj, M.D., Radium Institute, Patna, Patna Medical College and Hospital, India. Current Institution: Department of Radiotherapy, VMMC and Safdarjung Hospital, New Delhi, India. Tel No: +919334205252, +919711175159. Email: shraddharaj@yma.
authors.forename: R
authors.initials: R
authors.lastname: Shraddha
authors.affiliation: Radium Institute, Patna, Patna Medical College and Hospital, India.
authors.forename: P N
authors.initials: PN
authors.lastname: Pandit