title: Atopy patch test with Aleuroglyphus ovatus antigen in patients with atopic dermatitis.
abstract: BACKGROUND
  Epicutaneous test made with dust mite antigens.
  
  
  OBJECTIVE
  Evaluation of the response of the epicutaneous test with Aleuroglyphus ovatus antigen in atopic patients.
  
  
  METHODS
  We patch tested 119 individuals, 48 with atopic dermatitis, 50 with respiratory allergy and 21 healthy controls. We compare the positive response frequency to a closed patch test using Aleuroglyphus ovatus antigen in different concentrations and 48 and 96h reading times among those individuals.
  
  
  RESULTS
  Six patients with atopic dermatitis (12.5%) and 4 with respiratory atopy (8.0%) had positive reactions. None of the non-atopic controls had a positive response. As the antigen concentration raised, the number of positive reactions to epicutaneous test raised as well.
  
  
  CONCLUSIONS
  Our data suggest a positive relation between Atopy Patch Test positive responses and Aleuroglyphus ovatus antigen concentration, no matter the kind of the atopic clinical expression.
authors.affiliation: Dermatology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
authors.forename: D
authors.initials: D
authors.lastname: Lorenzini
authors.forename: M
authors.initials: M
authors.lastname: Pires
authors.forename: V
authors.initials: V
authors.lastname: Aoki
authors.forename: R
authors.initials: R
authors.lastname: Takaoka
authors.forename: R L
authors.initials: RL
authors.lastname: Souza
authors.forename: C
authors.initials: C
authors.lastname: Vasconcellos
mesh_terms: D040041:Acaridae / Q000276:immunology*; D000293:Adolescent; D000328:Adult; D000818:Animals; D000941:Antigens / Q000008:administration & dosage / Q000276:immunology; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D010328:Patch Tests; D012130:Respiratory Hypersensitivity / Q000276:immunology*; D055815:Young Adult
chemical_list: D000941:Antigens