title: Case for diagnosis. Pemphigoid gestationis.
abstract: Pemphigoid gestationis is a rare, autoimmune blistering dermatosis of pregnancy. No increase in fetal or maternal mortality has been demonstrated, but a greater prevalence of premature and small-for-gestational age babies has been reported. Topical and systemic corticosteroids and antihistamines are the manstay of treatment. The authors report a case of a 27-year-old woman at 28-weeks gestation with sudden onset of pruriginous vesicles and blisters in the abdomen and limbs. Systemic corticosteroids were introduced and maintained throughout gestation to prevent flares and tapered after the birth of a healthy child.
authors.affiliation: Coimbra University, Hospital Center, Dermatology Department, Coimbra, Portugal, MD, Resident in the Dermatology Department, Coimbra University Hospital Center- Coimbra, Portugal.
authors.forename: Rita
authors.initials: R
authors.lastname: Cabral
authors.affiliation: Coimbra University, Hospital Center, Dermatology Department, Coimbra, Portugal, MD, Resident in the Dermatology Department, Coimbra University Hospital Center- Coimbra, Portugal.
authors.forename: Vera
authors.initials: V
authors.lastname: Teixeira
authors.affiliation: Coimbra University, Hospital Center, Dermatology Department, Coimbra, Portugal, MD, Resident in the Dermatology Department, Coimbra University Hospital Center- Coimbra, Portugal.
authors.forename: Ana
authors.initials: A
authors.lastname: Brinca
authors.affiliation: Portuguese Oncology Institute of Coimbra, Dermatology Department, Coimbra, Portugal, Graduate in the Dermatology Department, Portuguese Oncology Institute of Coimbra - Coimbra, Portugal.
authors.forename: Barbara
authors.initials: B
authors.lastname: Fernandes
authors.affiliation: Coimbra University, Hospital Center, Dermatology Department, Coimbra, Portugal, Graduate in the Dermatology Department, Coimbra University Hospital Center - Coimbra, Portugal.
authors.forename: José Pedro
authors.initials: JP
authors.lastname: Reis
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D019085:Fluorescent Antibody Technique, Direct; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D006559:Pemphigoid Gestationis / Q000188:drug therapy / Q000473:pathology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D012867:Skin / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone