title: Photoprotective characteristics of natural antioxidant polyphenols.
abstract: Fourteen natural polyphenols belonging to the classes of stilbenes, flavonoids and hydroxycinnamic acid derivatives, have been investigated in order to verify the combination of their photoprotective characteristics with their antioxidant properties. To this purpose, sun protection factor (SPF), UVA/UVB ratio and critical wavelengths (λc), have been considered to evaluate photoprotection capacity, while inhibition of lipid peroxidation has been adopted as a reliable measure of the antioxidant properties. The results obtained indicate that a large number of these natural phenol derivatives show both antioxidant activity and photoprotective characteristics and, as a consequence, they could be interesting components for pharma-photoprotection formulations. In fact, these compounds associate to a preventive function, linked to UV filtering properties, an effective action, correlated to antioxidant capacity of contrast towards UV-induced ROS injury.
authors.affiliation: Department of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Dorsoduro 2137, 30123 Venice, Italy. Electronic address: roberto.stevanato@unive.it.
authors.forename: Roberto
authors.initials: R
authors.lastname: Stevanato
authors.affiliation: Department of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Dorsoduro 2137, 30123 Venice, Italy. Electronic address: bertelle@unive.it.
authors.forename: Mariangela
authors.initials: M
authors.lastname: Bertelle
authors.affiliation: Department of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Dorsoduro 2137, 30123 Venice, Italy. Electronic address: sabri@unive.it.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Fabris
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects; D059808:Polyphenols / Q000494:pharmacology*; D059405:Sun Protection Factor / Q000379:methods; D014466:Ultraviolet Rays / Q000009:adverse effects
chemical_list: D000975:Antioxidants; D059808:Polyphenols
keywords: Antioxidants; Polyphenols; Sunscreens