title: Aerobic oxidation in nanomicelles of aryl alkynes, in water at room temperature.
abstract: On the basis of the far higher solubility of oxygen gas inside the hydrocarbon core of nanomicelles, metal and peroxide free aerobic oxidation of aryl alkynes to β-ketosulfones has been achieved in water at room temperature. Many examples are offered that illustrate broad functional group tolerance. The overall process is environmentally friendly, documented by the associated low E Factors.
authors.affiliation: Department of Chemistry & Biochemistry, University of California, Santa Barbara, CA 93106 (USA).
authors.forename: Sachin
authors.initials: S
authors.lastname: Handa
authors.forename: James C
authors.initials: JC
authors.lastname: Fennewald
authors.forename: Bruce H
authors.initials: BH
authors.lastname: Lipshutz
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013696:Temperature; D014867:Water
chemical_list: D000480:Alkynes; D014867:Water
keywords: E Factor; TPGS-750-M; aerobic oxidation; hydrophobic effect; micellar catalysis