title: Esophageal/gastric cancer screening in high-risk populations in Henan Province, China.
abstract: OBJECTIVE
  To summarize the endoscopic screening findings in high-risk population of esophageal and gastric carcinoma and analyze influential factors related to screening.
  
  
  METHODS
  In seven selected cities and counties with high incidences of esophageal carcinoma, people at age of 40-69 were set as the target population. Those with gastroscopy contradictions were excluded, and all who were voluntary and willing to comply with the medical requirements were subjected to endoscopic screening and histological examination for esophageal, gastric cardia and gastric carcinoma in accordance with national technical manual for early detection and treatment of cancer.
  
  
  RESULTS
  In three years, 36,154 people were screened, and 16,847 (46.60%) cases were found to have precancerous lesions. A total of 875 cases were found to have cancers (2.42%), and among them 739 cases had early stage with an early diagnosis rate is 84.5%. Some 715 patients underwent prompt treatment and the success rate was 81.8%.
  
  
  CONCLUSIONS
  In a high-risk population of esophageal and gastric carcinoma, it is feasible to implement early detection and treatment by endoscopic screening. Screening can identify potential invasive carcinoma, early stage carcinoma and precancerous lesions, improving efficacy through early detection and treatment. The exploratory analysis of related influential factors will help broad implementation of early detection and treatment for esophageal and gastric carcinoma.
authors.affiliation: Department of Oncology, Shandong University, Departments of Radiation Oncology, Shandong Cancer Hospital and Institute, Jinan, China E-mail : hncjbl@Sohu.com.
authors.forename: Yu-Fei
authors.initials: YF
authors.lastname: Lu
authors.forename: Zhi-Cai
authors.initials: ZC
authors.lastname: Liu
authors.forename: Zhong-Hong
authors.initials: ZH
authors.lastname: Li
authors.forename: Wen-Hao
authors.initials: WH
authors.lastname: Ma
authors.forename: Fu-Rang
authors.initials: FR
authors.lastname: Wang
authors.forename: Ya-Bing
authors.initials: YB
authors.lastname: Zhang
authors.forename: Jian-Bang
authors.initials: JB
authors.lastname: Lu
mesh_terms: D000328:Adult; D000368:Aged; D002299:Cardia; D002681:China / Q000453:epidemiology; D055088:Early Detection of Cancer; D016145:Endoscopy, Digestive System; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D011230:Precancerous Conditions / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D013270:Stomach / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology