title: Perceptions of academic health science research center personnel regarding informed consent processes and therapeutic misconception.
abstract: BACKGROUND
  Instrumentation exists to measure voluntariness and misunderstanding in informed consent processes. However, research personnel's perspectives about using instrumentation to measure therapeutic misconceptions in research participants has not been reported. We designed a workshop to promote research personnel knowledge of emerging instrumentation and to study the perceptions of research personnel regarding such instruments.
  
  
  RESULTS
  Two nationally recognized experts who have developed psychometric instruments to measure aspects of informed consent presented their recent findings to research personnel of the Medical University of South Carolina at a one-day workshop. Following the presentations, workshop attendees divided into two focus groups and shared their perceptions regarding the presentation content. Inductive thematic analysis detected themes related to informed consent processes including: investigator/provider role clarity; investigator transparency; therapeutic misconception; and screening subjects for understanding.
  
  
  CONCLUSIONS
  Our findings suggest future directions in applied, proactive empirical research to better understand investigator perceptions and practices related to transparency in research, and to develop instrumentation to detect risks to the integrity of informed consent in order to promote voluntariness and autonomy and minimize therapeutic misconception in research practices.
authors.affiliation: a Medical University of South Carolina, Institute of Human Values in Health Care, South Carolina Clinical and Translational Research Institute , Charleston , South Carolina , USA.
authors.forename: Teresa W
authors.initials: TW
authors.lastname: Atz
authors.forename: Robert M
authors.initials: RM
authors.lastname: Sade
authors.forename: Pamela H
authors.initials: PH
authors.lastname: Williams
mesh_terms: D000046:Academic Medical Centers / Q000458:organization & administration; D001291:Attitude of Health Personnel; D032984:Ethics, Research; D005260:Female; D006801:Humans; D007258:Informed Consent / Q000941:ethics* / Q000523:psychology; D033183:Interdisciplinary Communication; D008297:Male; D009657:North Carolina; D017009:Professional Autonomy; D011594:Psychometrics; D012106:Research / Q000458:organization & administration*; D055990:Therapeutic Misconception / Q000941:ethics / Q000523:psychology*