title: Intensity modulated arc therapy in bilaterally irradiated head and neck cancer: a comparative and prospective multicenter planning study.
abstract: A dosimetric comparison was made of Helical Tomotherapy (HT) and Rapid'Arc(®) (RA) in 115 patients with head and neck carcinoma included in a prospective and multicentric study. HT and RA provided highly conformal plans that easily complied with dose volume constraints for organs at risk. HT reduced high doses to the planning target volumes (PTVs) compared to RA and provided a more homogeneous dose distribution but with an increased Non Tumoral Integral Dose (NTID) than RA. However, the clinical consequences of these dosimetric advantages and disadvantages need further investigation.
authors.affiliation: Department of Radiation Therapy, Besançon University Hospital, Besançon, France1.
authors.forename: Stéphanie Servagi
authors.initials: SS
authors.lastname: Vernat
authors.forename: David
authors.initials: D
authors.lastname: Ali
authors.forename: Caroline
authors.initials: C
authors.lastname: Messina
authors.forename: Pascal
authors.initials: P
authors.lastname: Pommier
authors.forename: Sophie
authors.initials: S
authors.lastname: Dussart
authors.forename: Marc
authors.initials: M
authors.lastname: Puyraveau
authors.forename: Romain
authors.initials: R
authors.lastname: Viard
authors.forename: Thomas
authors.initials: T
authors.lastname: Lacornerie
authors.forename: Albert
authors.initials: A
authors.lastname: Lisbona
authors.forename: Pascal
authors.initials: P
authors.lastname: Fenoglietto
authors.forename: Jocelyne
authors.initials: J
authors.lastname: Mazurier
authors.forename: Robin
authors.initials: R
authors.lastname: Garcia
authors.forename: Gregory
authors.initials: G
authors.lastname: Hangard
authors.forename: Sophia
authors.initials: S
authors.lastname: Zefkili
authors.forename: Libor
authors.initials: L
authors.lastname: Makovicka
authors.forename: Philippe
authors.initials: P
authors.lastname: Giraud
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011446:Prospective Studies; D011874:Radiometry / Q000009:adverse effects / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D050397:Radiotherapy, Intensity-Modulated / Q000009:adverse effects / Q000379:methods*; D055815:Young Adult