title: The importance of seeing surface (effects).
abstract: In this issue of Structure, Liu and colleagues describe an experimentally rigorous and innovative approach for understanding the role of membranes in the function and regulation of peripheral membrane proteins. This work is the beginning of a new era of experimental work that promises many advances relevant to molecular mechanisms and therapeutic targeting of this important class of proteins.
authors.affiliation: Biochemistry and Biophysics Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: James M
authors.initials: JM
authors.lastname: Gruschus
authors.affiliation: Structural Biophysics Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: R Andrew
authors.initials: RA
authors.lastname: Byrd
authors.affiliation: Laboratory of Cellular and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: randazzp@mail.nih.gov.
authors.forename: Paul A
authors.initials: PA
authors.lastname: Randazzo
mesh_terms: D020823:ADP-Ribosylation Factor 1 / Q000737:chemistry* / Q000378:metabolism*; D048868:Adaptor Proteins, Signal Transducing / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans
chemical_list: D048868:Adaptor Proteins, Signal Transducing; C487037:PLEKHA3 protein, human; D020823:ADP-Ribosylation Factor 1