title: Three-stranded antiviral attack.
abstract: Mitochondrial antiviral signalling proteins form an intricate three-stranded helical filament that has a central role in the response of cells to viruses.
authors.affiliation: Jenish R Patel is in the Department of Microbiology, and the Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, United States jenish.patel@mssm.edu.
authors.forename: Jenish R
authors.initials: JR
authors.lastname: Patel
authors.forename: Adolfo
authors.initials: A
authors.lastname: García-Sastre
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000737:chemistry* / Q000276:immunology*; D006801:Humans; D007113:Immunity, Innate; D008928:Mitochondria / Q000276:immunology*; D029082:Sendai virus / Q000276:immunology*
chemical_list: D048868:Adaptor Proteins, Signal Transducing
keywords: MAVS; cryoEM reconstruction; immune response; innate immunity; prion-like filaments; three-stranded filaments