title: A tiered approach to address regulatory drug metabolite-related issues in drug development.
authors.affiliation: Department of Drug Metabolism & Pharmacokinetics, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
authors.forename: Shuguang
authors.initials: S
authors.lastname: Ma
authors.forename: Swapan K
authors.initials: SK
authors.lastname: Chowdhury
mesh_terms: D054316:Biomarkers, Pharmacological / Q000032:analysis* / Q000378:metabolism; D055808:Drug Discovery / Q000379:methods*; D006801:Humans; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000378:metabolism*
chemical_list: D054316:Biomarkers, Pharmacological; D004364:Pharmaceutical Preparations