title: Role of miR-107 and its signaling pathways in diseases.
abstract: MicroRNAs exert their biologic effects by targeting specific mRNAs for degradation or translational inhibition. MicroRNA-mediated regulation is complex, potentially affecting expression of the host gene, related enzymes within the same pathway or apparently distinct targets. miR-107 is found to be implicated in the pathogenesis of some diseases. This review was performed to sum up the role of miR-107 and its signaling pathways in renal diseases.
authors.affiliation: Department of Nephrology, The Sixth Affiliated Hospital, Sun Yat-Sen University , Guangzhou , China.
authors.forename: Zong-Pei
authors.initials: ZP
authors.lastname: Jiang
authors.forename: Tian-Biao
authors.initials: TB
authors.lastname: Zhou
mesh_terms: D003424:Crohn Disease / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000378:metabolism*; D006801:Humans; D007674:Kidney Diseases / Q000378:metabolism*; D035683:MicroRNAs / Q000378:metabolism*; D009369:Neoplasms / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: C549045:MIRN107 microRNA, human; D035683:MicroRNAs
keywords: Diseases; miR-107; microRNAs; signaling pathways