title: Palladium-catalyzed C-H activation and intermolecular annulation with allenes.
abstract: A new and efficient Pd(II) -catalyzed intermolecular annulation of N-benzoylsulfonamide with allenes for the synthesis of 3,4-dihydroisoquinolin-1(2H)-ones is reported. This CH functionalization is compatible with ambient air and moisture, and it can be applied to terminal or internal allenes with diﬀerent synthetically attractive functional groups. Control experiments and a kinetic isotope effect study are conducted and a plausible mechanism is proposed.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000 (P.R. China), Fax: (+86) 931-8912582; School of Chemical and Material Engineering, Jiangnan University, Wuxi, 214122 (P.R. China).
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Xia
authors.forename: Yu-Qi
authors.initials: YQ
authors.lastname: Wang
authors.forename: Lu-Lu
authors.initials: LL
authors.lastname: Zhang
authors.forename: Xian-Rong
authors.initials: XR
authors.lastname: Song
authors.forename: Xue-Yuan
authors.initials: XY
authors.lastname: Liu
authors.forename: Yong-Min
authors.initials: YM
authors.lastname: Liang
keywords: CH activation; allenes; annulation; palladium; synthetic methods