title: Gathering around Firre.
abstract: Long noncoding RNAs (lncRNAs) have divergent roles in the nuclei of higher eukaryotes, including chromatin modification and regulation of nuclear bodies. A new study adds a new lncRNA function to the current list: serving as a platform for trans-chromosomal associations. At least three gene loci located on different chromosomes are brought together around the transcription site of a lncRNA termed functional intergenic repeating RNA element (Firre).
authors.affiliation: RNA Biology Laboratory, RIKEN, Wako, Japan.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Nakagawa
authors.affiliation: Chromosome Dynamics Laboratory, RIKEN, Wako, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Hirano
mesh_terms: D000818:Animals; D002875:Chromosomes / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008957:Models, Genetic; D062085:RNA, Long Noncoding / Q000502:physiology*
chemical_list: D062085:RNA, Long Noncoding