title: Ruthenium-catalyzed C7 amidation of indoline C-H bonds with sulfonyl azides.
abstract: A ruthenium-catalyzed direct C7 amidation of indoline C-H bonds with sulfonyl azides was developed. This procedure allows the synthesis of a variety of 7-amino-substituted indolines, which are useful in pharmaceutical. The good functional tolerances, as well as the mild conditions, are prominent feature of this method.
authors.affiliation: State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093 (P.R. China); Wenzhou Institute of Industry & Science, Wenzhou 325000 (P.R. China).
authors.forename: Changduo
authors.initials: C
authors.lastname: Pan
authors.forename: Ablimit
authors.initials: A
authors.lastname: Abdukader
authors.forename: Jie
authors.initials: J
authors.lastname: Han
authors.forename: Yixiang
authors.initials: Y
authors.lastname: Cheng
authors.forename: Chengjian
authors.initials: C
authors.lastname: Zhu
mesh_terms: D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012428:Ruthenium / Q000737:chemistry*; D013450:Sulfones / Q000737:chemistry*
chemical_list: D001386:Azides; D007211:Indoles; D013450:Sulfones; C057812:indoline; D012428:Ruthenium
keywords: CH activation; amidation; indolines; ruthenium; sulfonyl azides