title: Palladium-catalyzed alkenylation via sp2 C-H bond activation using phenolic hydroxyl as the directing group.
abstract: This note describes the efficient and highly regioselective synthesis of 2-(2'-alkenylphenyl)phenol derivatives via palladium-catalyzed 2'-alkenylation of 2-arylphenols directed by the phenolic hydroxyl group using benzoquinone as the oxidant in an atmosphere of air. This reaction can tolerate a series of functional groups and provides the alkenylation products regio- and stereoselectively in moderate to good yields.
authors.affiliation: Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University , Nanjing 210097, China.
authors.forename: Chun
authors.initials: C
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Ji
authors.forename: Peipei
authors.initials: P
authors.lastname: Sun
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D016227:Benzoquinones / Q000737:chemistry*; D002384:Catalysis; D006860:Hydrogen Bonding; D010165:Palladium / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D016227:Benzoquinones; D010636:Phenols; D010165:Palladium