title: DMAP promoted tandem addition reactions forming substituted tetrahydroxanthones.
abstract: Substituted tetrahydroxanthones are constructed using a DMAP-promoted tandem nucleophilic addition process. The reaction yields range from 39% to 73%. Disubstituted tetrahydroxanthones are generated as a ∼2.3:1 mixture of diastereomers favoring the formation of the trans-isomer.
authors.affiliation: Department of Chemistry, 2036 Main Mall, University of British Columbia , Vancouver, B.C., Canada , V6T 1Z1.
authors.forename: Emmanuel B
authors.initials: EB
authors.lastname: Castillo-Contreras
authors.forename: Gregory R
authors.initials: GR
authors.lastname: Dake
mesh_terms: D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism; D044004:Xanthones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: C417980:4-(dimethylamine)pyridine; D011725:Pyridines; D044004:Xanthones