title: Colonic basidiobolomycosis in a child: report of a culture-proven case.
abstract: Basidiobolomycosis is a rare fungal disease caused by Basidiobolus ranarum, which is endemic in tropical and subtropical regions of Africa, Asia, and Latin America. Gastrointestinal basidiobolomycosis poses diagnostic difficulties due to the non-specific clinical presentation and absence of predisposing factors. Eight pediatric cases of the disease have been reported recently from Iran, but none of these, or most of the other cases reported in the literature, has been proven by culture, which is the gold standard method for diagnosis. We present a case of culture-proven colonic basidiobolomycosis that occurred in a 3-year-old boy. The outcome was successful following surgical excision and antifungal therapy with posaconazole.
authors.affiliation: Department of Pathology, Dr Sheikh Children Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Nona
authors.initials: N
authors.lastname: Zabolinejad
authors.affiliation: Department of Parasitology and Mycology, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Naseri
authors.affiliation: Department of Radiology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Yasamin
authors.initials: Y
authors.lastname: Davoudi
authors.affiliation: Pediatric Surgery Department, Dr Sheikh Children Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Marjan
authors.initials: M
authors.lastname: Joudi
authors.affiliation: Department of Pediatrics and the Infection Control and Hand Hygiene Research Center, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: aelamimh@mums.ac.ir.
authors.forename: Mohammad Hassan
authors.initials: MH
authors.lastname: Aelami
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D002675:Child, Preschool; D003106:Colon / Q000382:microbiology / Q000473:pathology* / Q000601:surgery; D020091:Entomophthorales / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D008297:Male; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use; D020096:Zygomycosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery
chemical_list: D000935:Antifungal Agents; D014230:Triazoles; C101425:posaconazole
keywords: Basidiobolomycosis; Child; Gastrointestinal; Posaconazole