title: Enhancing the bioactivity of polymeric implants by means of cold gas spray coatings.
abstract: Nanostructured anatase coatings were built-up on biocompatible polyetheretherketone (PEEK) by means of cold gas spray (CGS). Titanium layer was previously desposited, which acted as bond coat between PEEK and metal oxide. Semicrystalline polymer was not degraded during the spraying process and starting composition of titanium dioxide was not affected. TiO₂ was homogeneously obtained onto CGS Ti layer and completely covered the piece. Primary human osteoblasts were seeded onto biomaterials and in vitro cell experiments provided evidence to confirm that nanostructured anatase coatings deposited by cold gas spray improve the performance of PEEK implants.
authors.affiliation: Thermal Spray Centre, CPT, University of Barcelona, Martí i Franquès, 1, 08028 Barcelona, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Gardon
authors.forename: H
authors.initials: H
authors.lastname: Melero
authors.forename: N
authors.initials: N
authors.lastname: Garcia-Giralt
authors.forename: S
authors.initials: S
authors.lastname: Dosta
authors.forename: I G
authors.initials: IG
authors.lastname: Cano
authors.forename: J M
authors.initials: JM
authors.lastname: Guilemany
mesh_terms: D001577:Benzophenones; D002478:Cells, Cultured; D006801:Humans; D020007:Implants, Experimental; D007659:Ketones / Q000737:chemistry*; D008422:Materials Testing; D010006:Osteoblasts / Q000166:cytology / Q000378:metabolism*; D011092:Polyethylene Glycols / Q000737:chemistry*; D011108:Polymers; D014025:Titanium / Q000737:chemistry*
chemical_list: D001577:Benzophenones; D007659:Ketones; D011108:Polymers; C009495:titanium dioxide; C063834:polyetheretherketone; D011092:Polyethylene Glycols; D014025:Titanium
keywords: cold gas spray; implant; nanostructure; polymer; titanium; titanium dioxide