title: [A case of Churg-Strauss syndrome with subarachnoid hemorrhage].
abstract: Churg-Strauss syndrome (CSS) is a vasculitis syndromes and is only rarely complicated by subarachnoid hemorrhage. In the current report, we describe a case of CSS with subarachnoid hemorrhage, which showed a favorable outcome following conservative treatment. A 68-year-old man with CSS on maintenance steroid therapy underwent MRI/A during tinnitus aggravation, and showed dilation of the left middle cerebral artery and stenosis of the peripheral area of the right vertebral artery. After 2 months, he presented sudden pain in the occipitocervical area, and CT revealed subarachnoid hemorrhage. Intracranial 3D CT-A and MRI/A showed the development of a protrusion at the base of the left anterior cerebral artery. Although both findings suggested cerebral artery dissection, the source of hemorrhage could not be identified. The 2009 Japanese Guidelines for the Management of Stroke recommends early diagnosis and treatment of hemorrhagic cerebral artery dissection because of the high risk of re-bleeding. However, considering the risks of vasculitis aggravation, development of systemic complications, and recurrence, conservative treatment was selected. In addition, owing to the risk of complications associated with the frequent use of iodinated contrast agents and angiography procedures, patient was followed up using MRI. His course was favorable, and he was discharged despite mild right abducens paralysis. When patients with hemorrhagic cerebral artery dissection have a history of allergic diseases, CCS should be considered; conservative treatment consisting of rest, strict blood pressure control, and steroid therapy may be the most appropriate option for certain patients.
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Yamagata University.
authors.forename: Miiko
authors.initials: M
authors.lastname: Ito
authors.forename: Naoki
authors.initials: N
authors.lastname: Kato
authors.forename: Ching-Chan
authors.initials: CC
authors.lastname: Su
authors.forename: Takamasa
authors.initials: T
authors.lastname: Kayama
mesh_terms: D000368:Aged; D020771:Anterior Cerebral Artery / Q000473:pathology*; D002533:Cerebral Angiography; D015267:Churg-Strauss Syndrome / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods; D008297:Male; D013345:Subarachnoid Hemorrhage / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis / Q000628:therapy