title: Characteristics of diagnosis and therapy of adolescent malignant ovarian tumors.
abstract: BACKGROUND
  To improve the early diagnosis rate of adolescent malignant ovarian tumors, avoid misdiagnosis, select proper therapy, avoid excessive therapy, and render therapy more tolerable.
  
  
  METHODS
  A comprehensive review of adolescent malignant ovarian tumors, such as types, difficulties of early diagnosis, therapeutic principles, prognosis, fertility preserving through the authors' clinical experience, with reference to Chinese and international literatures.
  
  
  CONCLUSIONS
  The majority of adolescent malignant tumors are malignant germ cell, the malignancy is high and it is difficult to diagnose in the early stage, likely to be ignored. Their diagnosis is therefore fundamental, while selecting the most appropriate therapeutic approach that also considers fertility-sparing without compromising prognosis and avoiding over-treatment.
authors.affiliation: Department of Gynecology and Obstetrics, Second Hospital of Jilin University, Changchun City, China.
authors.forename: M
authors.initials: M
authors.lastname: Su
authors.affiliation: Department of Biological Engineering, College of Pharmacy, Jilin University, Changchun City, China.
authors.forename: W
authors.initials: W
authors.lastname: Chang
authors.affiliation: Department of Biological Engineering, College of Pharmacy, Jilin University, Changchun City, China.
authors.forename: T
authors.initials: T
authors.lastname: Xu
authors.affiliation: Department of Biological Engineering, College of Pharmacy, Jilin University, Changchun City, China.
authors.forename: M
authors.initials: M
authors.lastname: Cui
authors.affiliation: Department of Biological Engineering, College of Pharmacy, Jilin University, Changchun City, China.
authors.forename: S
authors.initials: S
authors.lastname: Wu
authors.affiliation: Department of Biological Engineering, College of Pharmacy, Jilin University, Changchun City, China.
authors.forename: P
authors.initials: P
authors.lastname: Su
mesh_terms: D000293:Adolescent; D000077216:Carcinoma, Ovarian Epithelial; D004407:Dysgerminoma / Q000175:diagnosis / Q000628:therapy*; D042241:Early Diagnosis; D005260:Female; D059247:Fertility Preservation; D006801:Humans; D009375:Neoplasms, Glandular and Epithelial / Q000175:diagnosis / Q000628:therapy*; D059351:Organ Sparing Treatments; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000628:therapy*; D011379:Prognosis