title: Associations between maternal negative affect and adolescent's neural response to peer evaluation.
abstract: Parenting is often implicated as a potential source of individual differences in youths' emotional information processing. The present study examined whether parental affect is related to an important aspect of adolescent emotional development, response to peer evaluation. Specifically, we examined relations between maternal negative affect, observed during parent-adolescent discussion of an adolescent-nominated concern with which s/he wants parental support, and adolescent neural responses to peer evaluation in 40 emotionally healthy and depressed adolescents. We focused on a network of ventral brain regions involved in affective processing of social information: the amygdala, anterior insula, nucleus accumbens, and subgenual anterior cingulate, as well as the ventrolateral prefrontal cortex. Maternal negative affect was not associated with adolescent neural response to peer rejection. However, longer durations of maternal negative affect were associated with decreased responsivity to peer acceptance in the amygdala, left anterior insula, subgenual anterior cingulate, and left nucleus accumbens. These findings provide some of the first evidence that maternal negative affect is associated with adolescents' neural processing of social rewards. Findings also suggest that maternal negative affect could contribute to alterations in affective processing, specifically, dampening the saliency and/or reward of peer interactions during adolescence.
authors.affiliation: University of Pittsburgh, Western Psychiatric Institute and Clinic, USA. Electronic address: tanpz@upmc.edu.
authors.forename: Patricia Z
authors.initials: PZ
authors.lastname: Tan
authors.affiliation: University of Pittsburgh, Western Psychiatric Institute and Clinic, USA.
authors.forename: Kyung Hwa
authors.initials: KH
authors.lastname: Lee
authors.affiliation: University of California at Berkeley, School of Public Health, USA.
authors.forename: Ronald E
authors.initials: RE
authors.lastname: Dahl
authors.affiliation: Mood and Anxiety Disorders Program, National Institute of Mental Health, USA.
authors.forename: Eric E
authors.initials: EE
authors.lastname: Nelson
authors.affiliation: Department of Psychiatry and Human Behavior, Brown Medical School, USA.
authors.forename: Laura J
authors.initials: LJ
authors.lastname: Stroud
authors.affiliation: University of Pittsburgh, Western Psychiatric Institute and Clinic, USA.
authors.forename: Greg J
authors.initials: GJ
authors.lastname: Siegle
authors.affiliation: University of Pittsburgh, Western Psychiatric Institute and Clinic, USA.
authors.forename: Judith K
authors.initials: JK
authors.lastname: Morgan
authors.affiliation: University of Pittsburgh, Western Psychiatric Institute and Clinic, USA.
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Silk
mesh_terms: D000293:Adolescent; D041923:Adolescent Development; D000339:Affect; D000679:Amygdala / Q000502:physiology / Q000503:physiopathology; D001921:Brain / Q000502:physiology / Q000503:physiopathology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology / Q000503:physiopathology; D002648:Child; D003863:Depression / Q000503:physiopathology / Q000523:psychology; D004644:Emotions / Q000502:physiology; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D007206:Individuality; D008279:Magnetic Resonance Imaging; D008297:Male; D008425:Maternal Behavior / Q000523:psychology*; D009714:Nucleus Accumbens / Q000502:physiology / Q000503:physiopathology; D016487:Parenting / Q000523:psychology*; D010379:Peer Group; D012059:Rejection, Psychology; D012201:Reward
keywords: Adolescents; Amygdala; Parenting; Peer evaluation; Reward; Subgenual anterior cingulate cortex