title: 4',4‴,7,7″-tetra-O-methylcupressuflavone inhibits seed germination of Lactuca sativa.
abstract: Biflavonoids have been isolated from a wide variety of plant species, but little is known about their native biological functions. Here we report a possible ecological role for biflavonoids by describing the isolation of the biflavonoid 4',4‴,7,7″-tetra-O-methylcupressuflavone (1) from Araucaria columnaris and its inhibitory effect on seed germination. Compound 1 was isolated from needles of a single A. columnaris specimen and inhibited germination of Lactuca sativa seeds in a culture-dish assay; it was also detected in soil samples under the canopy where reduced germination was observed, but not in a location away from the canopy where germination was uninhibited.
authors.affiliation: Department of Chemistry, Natural Science Division, Pepperdine University , 24255 Pacific Coast Highway, Malibu, California 90263-4321 United States.
authors.forename: Jacob C
authors.initials: JC
authors.lastname: DeForest
authors.forename: Lin
authors.initials: L
authors.lastname: Du
authors.forename: P Matthew
authors.initials: PM
authors.lastname: Joyner
mesh_terms: D044946:Biflavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D018525:Germination / Q000187:drug effects*; D006254:Hawaii; D018545:Lactuca / Q000187:drug effects*; D015394:Molecular Structure; D028223:Pinus / Q000737:chemistry*; D012639:Seeds / Q000187:drug effects*
chemical_list: C000589538:4',4'',7,7'-tetra-O-methylcupressuflavone; D044946:Biflavonoids