title: Lewis acid catalyzed (3 + 2)-annulations of donor-acceptor cyclopropanes and ynamides.
abstract: The Sc(OTf)3-catalyzed (3 + 2)-annulation of donor-acceptor cyclopropanes and ynamides is described, providing the corresponding cyclopentene sulfonamides in good to excellent yield. Deprotection and hydrolysis of the resulting ensulfonamides delivers 2,3-substituted cyclopentanones with high diastereoselectivity.
authors.affiliation: Department of Chemistry, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-3290, United States.
authors.forename: William D
authors.initials: WD
authors.lastname: Mackay
authors.forename: Meryem
authors.initials: M
authors.lastname: Fistikci
authors.forename: Ryan M
authors.initials: RM
authors.lastname: Carris
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Johnson