title: Olfactory ensheathing cells seeded muscle-stuffed vein as nerve conduit for peripheral nerve repair: a nerve conduction study.
abstract: We evaluated bridging of 15 mm nerve gap in rat sciatic nerve injury model with muscle-stuffed vein seeded with olfactory ensheathing cells as a substitute for nerve autograft. Neurophysiological recovery, as assessed by electrophysiological analysis was faster in the constructed biological nerve conduit compared to that of autograft.
authors.affiliation: Tissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia.
authors.forename: Yogeswaran
authors.initials: Y
authors.lastname: Lokanathan
authors.affiliation: Tissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia.
authors.forename: Min-Hwei
authors.initials: MH
authors.lastname: Ng
authors.affiliation: Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Malaysia.
authors.forename: Shariful
authors.initials: S
authors.lastname: Hasan
authors.affiliation: Tissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia.
authors.forename: Anuar
authors.initials: A
authors.lastname: Ali
authors.affiliation: Tissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia.
authors.forename: Mazzre
authors.initials: M
authors.lastname: Mahmod
authors.affiliation: Department of Orthopaedic and Traumatology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia.
authors.forename: Ohnmar
authors.initials: O
authors.lastname: Htwe
authors.affiliation: Department of Orthopaedics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Malaysia.
authors.forename: Sharifah Ahmad
authors.initials: SA
authors.lastname: Roohi
authors.affiliation: Tissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia; Department of Physiology, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia.
authors.forename: Ruszymah
authors.initials: R
authors.lastname: Bt Hj Idrus
authors.affiliation: Department of Orthopaedic and Traumatology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia.
authors.forename: Shalimar
authors.initials: S
authors.lastname: Abdullah
authors.affiliation: Department of Orthopaedic and Traumatology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia. Electronic address: asnaicker@yahoo.com.
authors.forename: Amaramalar Selvi
authors.initials: AS
authors.lastname: Naicker
mesh_terms: D000818:Animals; D005260:Female; D018482:Muscle, Skeletal / Q000473:pathology; D009416:Nerve Regeneration; D009431:Neural Conduction; D009832:Olfactory Nerve / Q000473:pathology; D059348:Peripheral Nerve Injuries / Q000628:therapy; D017207:Rats, Sprague-Dawley; D044968:Regenerative Medicine; D012584:Sciatic Nerve / Q000473:pathology / Q000503:physiopathology*; D023822:Tissue Engineering; D014680:Veins / Q000473:pathology
keywords: Compound motor action potential; Latency; Muscle-stuffed vein; Nerve conduction study; Olfactory ensheathing cells