title: Congenital cystic lung disease: prenatal ultrasound and postnatal multidetector computer tomography evaluation. Correlation with surgical and pathological data.
abstract: OBJECTIVE
  The aim of this study was to evaluate the diagnostic accuracy of postnatal multidetector computed tomography (MDCT) compared with prenatal ultrasound (US), surgical findings, and histology, in 33 patients with congenital cystic lung disease.
  
  
  METHODS
  Thirty-three patients, 17 males and 16 females, were evaluated by MDCT. Twenty-seven of these patients underwent prenatal US between week 18 and 22, and between week 32 and 35 of gestation. Lung lobectomy, segmentectomy, atypical resection, lesion resection were performed in 31 patients and surgical specimens were analysed.
  
  
  RESULTS
  Prenatal US and MDCT correctly diagnosed 76.9 and 94 % of the lesions, respectively. Disagreement occurred in six lesions with prenatal US and in two lesions with MDCT. No statistically significant differences were observed between the two techniques (P = 0.122).
  
  
  CONCLUSIONS
  As most surgeons consider the surgical resection of these lesions mandatory, our study underscores the essential role of imaging, in particular CT, in providing invaluable preoperative information on congenital cystic lung diseases recognised in uterus.
authors.affiliation: Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy, bondioni.pia@tin.it.
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: Bondioni
authors.forename: Diego
authors.initials: D
authors.lastname: Gatta
authors.forename: Vassilios
authors.initials: V
authors.lastname: Lougaris
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Palai
authors.forename: Marino
authors.initials: M
authors.lastname: Signorelli
authors.forename: Silvia
authors.initials: S
authors.lastname: Michelini
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Di Gaetano
authors.forename: Paola
authors.initials: P
authors.lastname: Tessitore
authors.forename: Lorella
authors.initials: L
authors.lastname: Mascaro
authors.forename: Andrea
authors.initials: A
authors.lastname: Tironi
authors.forename: Giovanni
authors.initials: G
authors.lastname: Boroni
authors.forename: Roberto
authors.initials: R
authors.lastname: Maroldi
authors.forename: Daniele
authors.initials: D
authors.lastname: Alberti
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008171:Lung Diseases / Q000151:congenital* / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D061330:Multidetector Computed Tomography; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016216:Ultrasonography, Prenatal