title: Touch me not.
abstract: Central Poststroke Pain syndrome (CPSP) can occur due to disruption of the somatosensory pathways of the brain at any level such as the thalamus, medulla, or cerebral cortex. It is characterized by sensory abnormalities and hyperesthesia in the part of the body correlating to the central lesion. The treatment of this pain syndrome is often difficult, and it does not usually respond to traditional analgesics. The first line of treatment is drugs aimed at lowering neuronal hyperexcitability, for example, amitriptyline or lamotrigine, with gabapentin considered a second line.
authors.affiliation: Internal Medicine Department, Reading Health System, West Reading, PA, USA.
authors.forename: Paras
authors.initials: P
authors.lastname: Karmacharya
authors.affiliation: Internal Medicine Department, Mymensingh Medical College, Mymensingh, Bangladesh.
authors.forename: Kalpana
authors.initials: K
authors.lastname: Shah
authors.affiliation: Internal Medicine Department, Reading Health System, West Reading, PA, USA.
authors.forename: Ranjan
authors.initials: R
authors.lastname: Pathak
authors.affiliation: Internal Medicine Department, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
authors.forename: Sushil
authors.initials: S
authors.lastname: Ghimire
authors.affiliation: Internal Medicine Department, Reading Health System, West Reading, PA, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Alweis
keywords: Central Poststroke Pain; Déjerine Roussy syndrome; gabapentin; neuropathic pain; thalamic pain syndrome