title: Culturally appropriate education intervention on biospecimen research participation among Chinese Americans.
abstract: BACKGROUND
  Chinese Americans are at increased risk for hepatitis B virus (HBV) infection. To reduce or eliminate disparities in HBV-related infection rates, participation in scientific investigations of HBV risk and treatment, including biospecimen sampling, is important. However, Asian Americans have low rates of participation in biospecimen research, and little is known about how educational interventions affect knowledge and participation in HBV-related biospecimen research.
  
  
  METHODS
  Eight Chinese community-based organizations participated in a quasi-experimental, two-group design with education assessments at pre- and postworkshop and a 3-month follow-up. Four sites were randomly assigned to receive the intervention (n = 175) and four sites to receive general health education (control; n = 240).
  
  
  RESULTS
  Participant knowledge about biospecimen research increased from pre- to posteducation in the intervention but not in the control condition. Of intervention participants, 83.4% (146/175) donated one tube of blood for future HBV biospecimen research, and 50.9% (89/175) donated another tube of blood for HBV testing. In contrast, only 1.1% of participants in the control condition reported donating a blood sample at follow-up assessment.
  
  
  CONCLUSIONS
  The intervention program significantly increased knowledge of and participation in HBV biospecimen research among Chinese Americans. Community-based participatory research (CBPR) methods featured active support by community leaders, a culturally specific curriculum, and convenient, immediate access to blood sampling, which resulted in high donation rates.
  
  
  CONCLUSIONS
  HBV-related morbidity and mortality is an urgent problem faced by Chinese Americans. CBPR provides a model for engaging communities in early detection, vaccination, and treatment that can reduce this health threat.
authors.affiliation: Authors' Affiliations: Center for Asian Health, Temple University; Department of Public Health, College of Health Professions, Temple University; Cancer Prevention and Control Program, Fox Chase Cancer Center; University of Pennsylvania; Department of Pathology and Laboratory Medicine, Temple University Hospital and School of Medicine; Philadelphia Senior Center, Philadelphia, PA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center; and University of Kansas Cancer Center, Kansas City, Kansas.
authors.forename: Wanzhen
authors.initials: W
authors.lastname: Gao
authors.forename: Grace X
authors.initials: GX
authors.lastname: Ma
authors.forename: Yin
authors.initials: Y
authors.lastname: Tan
authors.forename: Carolyn
authors.initials: C
authors.lastname: Fang
authors.forename: Joellen
authors.initials: J
authors.lastname: Weaver
authors.forename: Ming
authors.initials: M
authors.lastname: Jin
authors.forename: Philip
authors.initials: P
authors.lastname: Lai
authors.forename: Andrew K
authors.initials: AK
authors.lastname: Godwin
mesh_terms: D001213:Asian / Q000523:psychology*; D018070:Biological Specimen Banks / Q000458:organization & administration* / Q000639:trends; D002681:China / Q000208:ethnology; D005260:Female; D006266:Health Education / Q000379:methods*; D007722:Health Knowledge, Attitudes, Practice; D054625:Healthcare Disparities; D006509:Hepatitis B / Q000097:blood / Q000208:ethnology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires