title: Audiovestibular findings in patients with Vogt-Koyanagi-Harada disease.
abstract: CONCLUSIONS
  The long-term follow-up study revealed a good audiovestibular prognosis in our patients with Vogt-Koyanagi-Harada disease (VKH) after adequate treatment.
  
  
  OBJECTIVE
  To evaluate the audiovestibular findings and long-term prognosis of patients with VKH.
  
  
  METHODS
  A total of 82 ears in 41 patients (9 males and 32 females, aged 18-78 years) with VKH were examined in the audiovestibular study. Of the 41 patients, 16 patients with follow-up periods of more than 12 months (13-158 months) were included in the long-term follow-up study. Audiovestibular examinations included pure-tone audiometry; positional, positioning, and spontaneous nystagmus tests; and a caloric test.
  
  
  RESULTS
  Among the 41 patients, 28 (68%) complained of auditory symptoms at the initial visit and 28 (68%) showed sensorineural hearing loss (SNHL). Of the 24 patients who underwent nystagmus tests, only 3 (13%) presented with vestibular symptoms whereas 11 (46%) had nystagmus. Among 32 ears in 16 patients enrolled in the long-term follow-up study, 19 ears showed SNHL at the initial visit. The SNHL returned to normal in 14 ears (74%) and remained minimal in severity in the other 5 ears (26%) at the last visit. None of the patients showed persistent or repetitive vestibular symptoms.
authors.affiliation: Department of Otolaryngology.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Noguchi
authors.forename: Ayako
authors.initials: A
authors.lastname: Nishio
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takase
authors.forename: Masaru
authors.initials: M
authors.lastname: Miyanaga
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Takahashi
authors.forename: Manabu
authors.initials: M
authors.lastname: Mochizuki
authors.forename: Ken
authors.initials: K
authors.lastname: Kitamura
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001301:Audiometry, Pure-Tone; D002150:Caloric Tests; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000209:etiology / Q000469:parasitology; D006801:Humans; D008297:Male; D008875:Middle Aged; D004856:Postural Balance / Q000502:physiology*; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D014722:Vestibule, Labyrinth / Q000503:physiopathology*; D055815:Young Adult