title: Co-occurrence of acanthosis nigricans and bladder adenocarcinoma - case report.
abstract: Acanthosis nigricans (AN) is characterized by the occurrence of symmetrical velvety hyperpigmented plaques that can be observed in each location on the skin. However, the lesions are most frequently located in the axillary, inguinal and nuchal areas. Primarily, the lesions appear as hyperpigmented focuses which later transform into papillary lesions. There are two forms of the disease - benign and malignant. Malignant AN is considered to represent paraneoplastic syndrome co-occurring with advanced cancer, but as such it is not malignant. This article presents a case of a patient diagnosed with AN and coexisting bladder cancer and discusses the case in the context of available literature.
authors.affiliation: Department and Clinic of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Karolina
authors.initials: K
authors.lastname: Olek-Hrab
authors.affiliation: Department and Clinic of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Silny
authors.affiliation: Department and Clinic of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Ryszard
authors.initials: R
authors.lastname: Zaba
authors.affiliation: Department and Clinic of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Osmola-Mańkowska
authors.affiliation: Department and Clinic of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Mackiewicz-Wysocka
authors.affiliation: Department and Clinic of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Dańczak-Pazdrowska
keywords: acanthosis nigricans; paraneoplastic syndrome