title: Experience with the use of Hemopure in the care of a massively burned adult.
abstract: OBJECTIVE
  To report the use of a bovine hemoglobin-based oxygen carrier (HBOC-201) in an elderly patient sustaining extensive thermal injury unable to receive allogenic transfusion due to religious preference.
  
  
  METHODS
  Case report and literature review describing steps required for acquisition and safe infusion of HBOC-201.
  
  
  RESULTS
  Six units of HBOC-201 were infused in the perioperative period for anemia with signs of critically low oxygen delivery without adverse sequelae. The patient ultimately died as a result of multiple organ failure.
  
  
  CONCLUSIONS
  Despite disappointing results of the use of HBOCs in other patient populations, there is a role for compassionate, emergency use of cell-free hemoglobin in the management of burn patients unable to receive allogenic blood products.
authors.affiliation: U.S. Army Institute of Surgical Research Fort Sam Houston, TX, USA.
authors.forename: Jonathan B
authors.initials: JB
authors.lastname: Lundy
authors.affiliation: U.S. Army Institute of Surgical Research Fort Sam Houston, TX, USA.
authors.forename: Clayton J
authors.initials: CJ
authors.lastname: Lewis
authors.affiliation: U.S. Army Institute of Surgical Research Fort Sam Houston, TX, USA.
authors.forename: Leopoldo C
authors.initials: LC
authors.lastname: Cancio
authors.affiliation: U.S. Army Institute of Surgical Research Fort Sam Houston, TX, USA.
authors.forename: Andrew P
authors.initials: AP
authors.lastname: Cap
keywords: Burns; anemia; hemoglobin-based oxygen carriers; transfusion