title: γ-Halo-enones: a method for their synthesis from arylacyl halides and their application to the preparation of five-membered ring heterocycles.
abstract: A simple method has been developed for synthesis of γ-halo-enones. The approach employs a sequence involving initial indium-mediated allenylation reactions of phenacyl halides with propargyl bromide. This process is followed by acid-promoted rearrangement reactions of the formed homoallenic halohydrins. The new method can be incorporated into routes for the efficient synthesis of various five-membered heterocyclic compounds.
authors.affiliation: Department of Chemistry, National Changhua University of Education , Changhua, Taiwan 50007.
authors.forename: Mei-Huey
authors.initials: MH
authors.lastname: Lin
authors.forename: Yen-Chih
authors.initials: YC
authors.lastname: Huang
authors.forename: Chung-Kai
authors.initials: CK
authors.lastname: Kuo
authors.forename: Chang-Hsien
authors.initials: CH
authors.lastname: Tsai
authors.forename: Yi-Syuan
authors.initials: YS
authors.lastname: Li
authors.forename: Ting-Chia
authors.initials: TC
authors.lastname: Hu
authors.forename: Tsung-Hsun
authors.initials: TH
authors.lastname: Chuang