title: Hydroxyurea-induced leg ulceration in a patient with a homozygous MTHFR polymorphism misdiagnosed as pyoderma gangrenosum.
authors.forename: Sunita C
authors.initials: SC
authors.lastname: Crittenden
authors.forename: Juliana E
authors.initials: JE
authors.lastname: Gilbert
authors.forename: Jeffrey P
authors.initials: JP
authors.lastname: Callen
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000009:adverse effects*; D007871:Leg Ulcer / Q000139:chemically induced* / Q000235:genetics; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics*; D009190:Myelodysplastic Syndromes / Q000188:drug therapy; D011110:Polymorphism, Genetic; D017511:Pyoderma Gangrenosum / Q000175:diagnosis*; D014945:Wound Healing / Q000235:genetics
chemical_list: D000970:Antineoplastic Agents; C573423:MTHFR protein, human; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D006918:Hydroxyurea