title: Molecular architecture of tailed double-stranded DNA phages.
abstract: The tailed double-stranded DNA bacteriophages, orCaudovirales, constitute ~96% of all the known phages. Although these phages come in a great variety of sizes and morphology, their virions are mainly constructed of similar molecular building blocks via similar assembly pathways. Here we review the structure of tailed double-stranded DNA bacteriophages at a molecular level, emphasizing the structural similarity and common evolutionary origin of proteins that constitute these virions.
authors.affiliation: Department of Biological Sciences; Purdue University; West Lafayette, IN USA.
authors.forename: Andrei
authors.initials: A
authors.lastname: Fokine
authors.affiliation: Department of Biological Sciences; Purdue University; West Lafayette, IN USA.
authors.forename: Michael G
authors.initials: MG
authors.lastname: Rossmann
keywords: Caudovirales; bacteriophage structure; phage proteins; phage tails; tailed double-stranded DNA bacteriophages; virus capsids; virus structure