title: Transcatheter aortic valve implantation: from fantasy to reality.
abstract: Increased life expectancy has led to the presentation of more complicated patients in old age for the replacement of the aortic valve. The emergence of Transcatheter Aortic Valve Implantation (TAVI) was considered as a significant breakthrough in the management of symptomatic, moribund patients suffering from aortic valve stenosis who had been rejected for surgical intervention. A novel technology often has a long journey from the point at which it is created to its every-day-use. It is now obvious that TAVI practice in multiple institutes around the world has gone beyond the evidence. Serious concerns have been raised questioning the current TAVI practice. Analysis of future TAVI use may assist clinicians and healthcare managers to understand and deploy this technology in accordance with the evidence.
authors.affiliation: Department of Cardiothoracic Surgery, Golden Jubilee National Hospital, Glasgow, Clydebank G81 4DY, UK. kasrash@gmail.com.
authors.forename: Kasra
authors.initials: K
authors.lastname: Shaikhrezai
authors.forename: Billy
authors.initials: B
authors.lastname: McWilliams
authors.forename: Edward T
authors.initials: ET
authors.lastname: Brackenbury
authors.forename: Sai
authors.initials: S
authors.lastname: Prasad
authors.forename: Tristan D
authors.initials: TD
authors.lastname: Yan
authors.forename: Renzo
authors.initials: R
authors.lastname: Pessotto
authors.forename: Vipin
authors.initials: V
authors.lastname: Zamvar
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Berg
mesh_terms: D001021:Aortic Valve / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000601:surgery; D006328:Cardiac Catheterization; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000379:methods* / Q000592:standards / Q000639:trends; D006801:Humans