title: Polycystic ovarian syndrome and congenital uterine anomalies: the hidden common player.
abstract: OBJECTIVE
  To study the association between polycystic ovary syndrome (PCOS) and congenital uterine (Müllerian) anomalies in infertile patients. The ultimate aim was to check for a common factor linking both reproductive health problems.
  
  
  METHODS
  A prospective observational study.
  
  
  METHODS
  Tertiary referral infertility center.
  
  
  METHODS
  3,900 infertile patients were included. The diagnoses of PCOS and uterine anomalies were made. Patients with or without PCOS were correlated to the presence or absence of uterine anomalies and statistically assessed.
  
  
  METHODS
  Study of the prevalence of PCOS/uterine anomalies in the studied population and the ratio of coexistence.
  
  
  RESULTS
  The prevalence of PCOS in the studied cohort was 10.48 %. 409 (10.48 %) patients were confirmed to have PCOS, while 204 (5.23 %) were with confirmed uterine anomalies. Of the patients with confirmed PCOS, almost one-third (n = 149, 31.4 %) had uterine anomalies, while in patients with confirmed uterine anomalies, almost three-fourths (n = 149, 73 %) had PCOS.
  
  
  CONCLUSIONS
  There is evident association between PCOS and uterine anomalies in infertile patients. We suggest a genetic rather than a developmental defect to be a possible common player for the development of both PCOS and uterine anomalies.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
authors.forename: Hisham Ali
authors.initials: HA
authors.lastname: Saleh
authors.forename: Fady M
authors.initials: FM
authors.lastname: Shawky Moiety
mesh_terms: D000328:Adult; D004534:Egypt / Q000453:epidemiology; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology; D011085:Polycystic Ovary Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D014463:Ultrasonography; D014564:Urogenital Abnormalities / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology; D014599:Uterus / Q000002:abnormalities* / Q000000981:diagnostic imaging