title: A direct access to bioactive fused N-heterocyclic acetic acid derivatives.
abstract: A Cu-catalyzed new sequence involving the Ullmann type intermolecular C-C followed by an intramolecular C-N coupling and then intramolecular aza-Michael type addition (and oxidation) in a single pot afforded various fused N-heterocyclic acetic acid derivatives as inhibitors of PDE4.
authors.affiliation: Dr Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India. manojitpal@rediffmail.com.
authors.forename: Raju
authors.initials: R
authors.lastname: Adepu
authors.forename: A
authors.initials: A
authors.lastname: Rajitha
authors.forename: Dipali
authors.initials: D
authors.lastname: Ahuja
authors.forename: Atul Kumar
authors.initials: AK
authors.lastname: Sharma
authors.forename: B
authors.initials: B
authors.lastname: Ramudu
authors.forename: Ravikumar
authors.initials: R
authors.lastname: Kapavarapu
authors.forename: Kishore V L
authors.initials: KV
authors.lastname: Parsa
authors.forename: Manojit
authors.initials: M
authors.lastname: Pal
mesh_terms: D019342:Acetic Acid / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure
chemical_list: D006571:Heterocyclic Compounds; D003300:Copper; D019342:Acetic Acid