title: Estimation of Circulating Immune Complexes in patients with Oral Leukoplakia and Oral Submucous Fibrosis: A Case Control Study.
abstract: OBJECTIVE
  The present study was conducted to estimate the serum levels of Circulating Immune Complexes in patients with Oral Leukoplakia ,Oral sub mucous fibrosis and normal subjects and correlate these values with the clinical grades of the diseases.
  
  
  METHODS
  The study consisted of 25 Oral Leukoplakia patients, 25 Oral sub mucous fibrosis patients and 25 Normal subjects.
  
  
  RESULTS
  The mean serum levels of CIC showed a gradual increase from normal subjects to Oral Leukoplakia patients and showed a high values in Oral sub mucous fibrosis patients. The mean serum levels of CIC also showed a gradual increase from clinical grade I to grade IV of Oral sub mucous fibrosis.
  
  
  CONCLUSIONS
  Serum levels of CIC may be taken as a prognostic marker for disease progression of patients with Oral Leukoplakia and Oral sub mucous fibrosis.
authors.affiliation: Senior Lecturer, Department of Oral Medicine and Radiology, MaharanaPrathap College of Dentistry and Research Centre , Gwalior, Madhya Pradesh, India .
authors.forename: Maheswari
authors.initials: M
authors.lastname: H
authors.affiliation: Senior lecturer, Department of Prosthodontics, Thai moogambigai Dental college , Mugappair,Chennai, Tamilnadu, India .
authors.forename: Eswaran
authors.initials: E
authors.lastname: M A
authors.affiliation: Senior lecturer, Department of Oral Medicine and Radiology, Ragas Dental College & Hospital , Uthandi, Chennai,Tamilnadu, India .
authors.forename: Srividhya
authors.initials: S
authors.lastname: S
authors.affiliation: Senior lecturer, Department of Oral Medicine and Radiology, Ragas Dental College & Hospital , Uthandi,Chennai, Tamilnadu, India .
authors.forename: Malavika
authors.initials: M
authors.lastname: R
authors.affiliation: Reader, Department of Prosthodontics, Thai moogambigai Dental College , Mugappair, Chennai, Tamilnadu, India .
authors.forename: Prabhu
authors.initials: P
authors.lastname: R
authors.affiliation: Reader, Department of Prosthodontics, Thai moogambigai Dental College , Mugappair, Chennai, Tamilnadu, India .
authors.forename: Geetha
authors.initials: G
authors.lastname: K R
keywords: Poly Ethylene Glycol-6000 (PEG); Potentially malignant lesions and conditions; White lesions