title: The feasibility of an experimental model of donors after cardiac death in remote ischemic preconditioning studies for renal transplantation in porcine.
abstract: OBJECTIVE
  To evaluate the feasibility of an experimental model of donors after cardiac death in remote ischemic preconditioning studies.
  
  
  METHODS
  Twelve Landrace pigs were used as organ donors. They underwent cardiac arrest by coronary en block suture and interruption of ventilatory support. Haemodynamic data regarding the donor surgical protocol were evaluated. Studies variables included mean heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure, central venous pressure and oxygen saturation and the time to death.
  
  
  RESULTS
  Haemodynamic parameter indicated that the circulatory failure occurred after nine minutes of en block coronary suture and respiratory support interruption. The circulatory collapse occurred evenly across all groups. The heart rate and central venous pressure were statistically different between groups (p=0.023 and p=0.04), respectively. The remote preconditioning resulted in delayed time of death.
  
  
  CONCLUSIONS
  The model is feasible, and was easily reproduced. The ischemic remote preconditioning tends to a slight increase in circulatory failure time.
authors.affiliation: Federal University of Goias, GoianiaGO, Brazil, Fellow Master degree, Postgraduate Program in Health Sciences, Federal University of Goias (UFG), Goiania-GO, Brazil. Intellectual and scientific contents of the study, technical procedures, manuscript writing.
authors.forename: João Paulo Figueiredo
authors.initials: JP
authors.lastname: Camarço
authors.affiliation: UFG, GoianiaGO, Brazil, Fellow Master degree, Postgraduate Program in Health Sciences, UFG, Goiania-GO, Brazil. Acquisition and interpretation of data, manuscript writing.
authors.forename: Lucio Kenny
authors.initials: LK
authors.lastname: Morais
authors.affiliation: UFG, School of Veterinary and Animal Science, GoianiaGO, Brazil, PhD, Associate Professor, Anesthesiology, School of Veterinary and Animal Science (EVZ), UFG, Goiania-GO, Brazil. Intellectual and scientific content of the study, technical procedures, manuscript writing.
authors.forename: Juan Duque
authors.initials: JD
authors.lastname: Moreno
authors.affiliation: UFG, GoianiaGO, Brazil, Fellow Master degree, Postgraduate Program in Health Sciences, UFG, Goiania-GO, Brazil. Acquisition and interpretation of data, manuscript writing.
authors.forename: Matheus Castrillon
authors.initials: MC
authors.lastname: Rassi
authors.affiliation: Pontifical Catholic University of Goias, Department of Obstetrics/Gynecology, GoianiaGO, Brazil, Assistant Professor, Department of Obstetrics/Gynecology, Pontifical Catholic University of Goias (UCG), Goiania-GO, Brazil. Critical revision.
authors.forename: Mylena Naves de Castro Rocha
authors.initials: MN
authors.lastname: Camarço
authors.affiliation: Catholic University of Brasilia, Departament of Surgery, BrasiliaDF, Graduate student, Departament of Surgery, Catholic University of Brasilia (UCB), Brasilia-DF. Acquisition of data, technical procedures.
authors.forename: Pedro Figueiredo
authors.initials: PF
authors.lastname: Guimarães
authors.affiliation: UFG, GoianiaGO, Brazil, PhD, Associate Professor, Surgical Clinics, UFG, Goiania-GO, Brazil. Intellectual and scientific contents of the study, technical procedures, manuscript writing.
authors.forename: Claudemiro
authors.initials: C
authors.lastname: Quireze Júnior
mesh_terms: D000818:Animals; D001794:Blood Pressure; D003643:Death; D005240:Feasibility Studies; D006323:Heart Arrest / Q000503:physiopathology; D006339:Heart Rate; D019194:Ischemic Preconditioning / Q000379:methods*; D007668:Kidney / Q000098:blood supply*; D016030:Kidney Transplantation; D008297:Male; D023421:Models, Animal; D010100:Oxygen / Q000097:blood; D015203:Reproducibility of Results; D013552:Swine; D013997:Time Factors
chemical_list: D010100:Oxygen