title: Lupus erythematosus: considerations about clinical, cutaneous and therapeutic aspects.
abstract: Systemic Lupus Erythematosus is a chronic inflammatory disease with multifactorial etiology. Although clinical manifestations are varied, the skin is an important target-organ, which contributes to the inclusion of skin lesions in 4 out of the 17 new criteria for the diagnosis of the disease, according to the Systemic Lupus International Collaborating Clinics. The cutaneous manifestations of lupus are pleomorphic. Depending on their clinical characteristics, they can be classified into Acute Cutaneous Lupus Erythematosus, Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus and Intermittent Cutaneous Lupus Erythematosus. Treatment is based on preventive measures, reversal of inflammation, prevention of damage to target organs and relief of adverse events due to pharmacological therapy. The most commonly used treatment options are topical, systemic and surgical treatment, as well as phototherapy. The correct handling of the cases depends on a careful evaluation of the morphology of the lesions and the patient's general status, always taking into consideration not only the benefits but also the side effects of each therapeutic proposal.
authors.affiliation: Paraiba Federal University, João PessoaPB, Brazil, Medical Students Paraiba Federal University (UFPB) - João Pessoa (PB), Brazil.
authors.forename: Jucélio Pereira
authors.initials: JP
authors.lastname: Moura Filho
authors.affiliation: Paraiba Federal University, João PessoaPB, Brazil, Medical Students Paraiba Federal University (UFPB) - João Pessoa (PB), Brazil.
authors.forename: Raiza Luna
authors.initials: RL
authors.lastname: Peixoto
authors.affiliation: Paraiba Federal University, João PessoaPB, Brazil, Medical Students Paraiba Federal University (UFPB) - João Pessoa (PB), Brazil.
authors.forename: Lívia Gomes
authors.initials: LG
authors.lastname: Martins
authors.affiliation: Paraiba Federal University, João PessoaPB, Brazil, Medical Students Paraiba Federal University (UFPB) - João Pessoa (PB), Brazil.
authors.forename: Sillas Duarte de
authors.initials: SD
authors.lastname: Melo
authors.affiliation: Paraiba Federal University, João PessoaPB, Brazil, Medical Students Paraiba Federal University (UFPB) - João Pessoa (PB), Brazil.
authors.forename: Ligiana Leite de
authors.initials: LL
authors.lastname: Carvalho
authors.affiliation: Paraiba Federal University, Morphology Department, João PessoaPB, Brazil, DDS, PhD in Stomatology - Adjunct Professor at the Morphology Department at Paraiba Federal University (UFPB) - João Pessoa (PB), Brazil.
authors.forename: Ana Karine F da Trindade C
authors.initials: AK
authors.lastname: Pereira
authors.affiliation: Paraiba Federal University, João PessoaPB, Brazil, MD, PhD in Rheumatology - Professor of Rheumatology at Paraiba Federal University (UFPB) - João Pessoa (PB), Brazil.
authors.forename: Eutilia Andrade Medeiros
authors.initials: EA
authors.lastname: Freire
mesh_terms: D005260:Female; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000473:pathology* / Q000628:therapy*; D008180:Lupus Erythematosus, Systemic / Q000473:pathology* / Q000628:therapy*; D008297:Male; D012307:Risk Factors; D012867:Skin / Q000473:pathology