title: Genomic medicine implementation: learning by example.
abstract: Genomic Medicine is beginning to emerge into clinical practice. The National Human Genome Research Institute's Genomic Medicine Working Group consists of organizations that have begun to implement some aspect of genomic medicine (e.g., family history, systematic implementation of Mendelian disease program, pharmacogenomics, whole exome/genome sequencing). This article concisely reviews the working group and provides a broader context for the articles in the special issue including an assessment of anticipated provider needs and ethical, legal, and social issues relevant to the implementation of genomic medicine. The challenges of implementation of innovation in clinical practice and the potential value of genomic medicine are discussed.
authors.forename: Marc S
authors.initials: MS
authors.lastname: Williams
mesh_terms: D005826:Genetics, Medical / Q000379:methods* / Q000639:trends; D023281:Genomics / Q000379:methods* / Q000639:trends; D006801:Humans; D008487:Medical History Taking; D054560:National Human Genome Research Institute (U.S.); D010597:Pharmacogenetics / Q000379:methods* / Q000639:trends; D057170:Translational Research, Biomedical / Q000379:methods* / Q000639:trends; D014481:United States
keywords: ethical legal and social issues; family history; genomic medicine; implementation; personalized medicine; pharmacogenetics