title: Early hemodynamic resuscitation in septic shock: understanding and modifying oxygen delivery.
abstract: In a previous issue of Critical Care, researchers have focused on the venous-to-arterial carbon dioxide difference (Pv-aCO2) as a surrogate marker for systemic perfusion in patients with septic shock. Although the complex mechanisms responsible for an increased Pv-aCO2 in septic shock need to be further unraveled, the potential prognostic value of Pv-aCO2 seems clinically relevant and useful in daily practice in view of its easy availability.
authors.forename: Paul A
authors.initials: PA
authors.lastname: van Beest
authors.forename: Peter E
authors.initials: PE
authors.lastname: Spronk
mesh_terms: D032882:Comprehension; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D010100:Oxygen / Q000008:administration & dosage*; D010101:Oxygen Consumption / Q000502:physiology*; D012151:Resuscitation / Q000379:methods*; D012772:Shock, Septic / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors
chemical_list: D010100:Oxygen