title: First experience of carbon-ion radiotherapy for early breast cancer.
abstract: Breast cancer is increasingly being detected at earlier stages, and partial breast irradiation for patients with low-risk-group tumor has come to be applied in the US and Europe as an alternative to whole-breast irradiation. Based on those experiences, some institutes have tried using particle beams for partial breast irradiation for postoperative or radical intent for early breast cancer, but technical difficulties have hindered its progress. The National Institute of Radiological Sciences has been preparing for carbon-ion radiotherapy (C-ion RT) with radical intent for stage I breast cancer since 2011, and we carried out the first treatment in April 2013. In this case report, we explain our first experience of C-ion RT as a treatment procedure for breast tumor and present the radiation techniques and preliminary treatment results as a reference for other institutes trying to perform the same kind of treatment.
authors.affiliation: Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan, printemp.hs@gmail.com.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Akamatsu
authors.forename: Kumiko
authors.initials: K
authors.lastname: Karasawa
authors.forename: Tokuhiko
authors.initials: T
authors.lastname: Omatsu
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Isobe
authors.forename: Risa
authors.initials: R
authors.lastname: Ogata
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Koba
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D002244:Carbon / Q000627:therapeutic use*; D003287:Contrast Media; D019583:Dose Fractionation, Radiation; D005260:Female; D063193:Heavy Ion Radiotherapy / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D011879:Radiotherapy Dosage; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D002244:Carbon