title: A facile approach to prepare a dual functionalized DNA based material in a bio-deep eutectic solvent.
abstract: DNA (Salmon testes) was functionalized by Fe3O4 nanoparticles and protonated layered dititanate sheets (H2·Ti2O5·H2O) in a mixture of choline chloride and ethylene glycol (a deep eutectic solvent) to yield a hybrid material having magnetic and antibacterial properties. Ti sheets were found to interact with the phosphate moieties, while Fe interacted with the base pair of DNA in the hybrid material.
authors.affiliation: Marine Biotechnology and Ecology Discipline, CSIR-Central Salt and Marine Chemicals Research Institute (CSIR-CSMCRI), Council of Scientific & Industrial Research (CSIR), Gijubhai Badheka Marg, Bhavnagar-364 002, Gujarat, India. kamlesh@csmcri.org drkamaleshp@gmail.com.
authors.forename: Dibyendu
authors.initials: D
authors.lastname: Mondal
authors.forename: Jitkumar
authors.initials: J
authors.lastname: Bhatt
authors.forename: Mukesh
authors.initials: M
authors.lastname: Sharma
authors.forename: Shruti
authors.initials: S
authors.lastname: Chatterjee
authors.forename: Kamalesh
authors.initials: K
authors.lastname: Prasad
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects; D002794:Choline / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000187:drug effects; D019855:Ethylene Glycol / Q000737:chemistry*; D060328:Magnetic Phenomena; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D010316:Particle Size; D011551:Pseudomonas fluorescens / Q000187:drug effects; D012763:Shigella flexneri / Q000187:drug effects; D012997:Solvents / Q000737:chemistry; D013329:Structure-Activity Relationship; D013499:Surface Properties
chemical_list: D000900:Anti-Bacterial Agents; D058185:Magnetite Nanoparticles; D012997:Solvents; D004247:DNA; D019855:Ethylene Glycol; D002794:Choline