title: Palladium-catalyzed alkoxycarbonylation of terminal alkenes to produce α,β-unsaturated esters: the key role of acetonitrile as a ligand.
abstract: A mild protocol has been developed for the Pd(II)-catalyzed alkoxycarbonylation of terminal olefins to produce α,β-unsaturated esters with a wide range of substrates. Key features are the use of MeCN as solvent (and/or ligand) to control the reactivity of the intermediate Pd complexes and the combination of CO with O2, which facilitates the Cu(II)-mediated reoxidation of the Pd(0) complex to Pd(II) and prevents double carbonylation.
authors.affiliation: Chemistry Department, Loughborough University, Leicestershire, LE11 3TU (UK), Fax: (+44) 1509 22 3925. A.Malkov@lboro.ac.uk.
authors.forename: Andrei V
authors.initials: AV
authors.lastname: Malkov
authors.forename: Nolwenn
authors.initials: N
authors.lastname: Derrien
authors.forename: Maciej
authors.initials: M
authors.lastname: Barłóg
authors.forename: Pavel
authors.initials: P
authors.lastname: Kočovský
keywords: carbonylation; homogeneous catalysis; oxygen; palladium; solvent effects