title: Something to Reed about: fibroids, cutaneous leiomyomas, and renal cell carcinoma.
abstract: A 48 year-old woman with a history of fibroids presents with asymptomatic skin lesions. Biopsy reveals cutaneous leiomyomas and subsequent genetic evaluation confirms the diagnosis of hereditary leiomyomatosis and renal cell cancer. In this report, we review the typical presentation of the syndrome as well as recommendations for surveillance.
authors.affiliation: School of Medicine, University of Virginia, Charlottesville, VA.
authors.forename: Meredith L
authors.initials: ML
authors.lastname: Orseth
authors.affiliation: Department of Obstetrics and Gynecology, University of Virginia, Charlottesville, VA.
authors.forename: Dana
authors.initials: D
authors.lastname: Redick
authors.affiliation: Department of Pathology, University of Virginia, Charlottesville, VA.
authors.forename: Joel
authors.initials: J
authors.lastname: Pinczewski
authors.affiliation: Department of Dermatology, University of Virginia, Charlottesville, VA.
authors.forename: Barbara B
authors.initials: BB
authors.lastname: Wilson
authors.affiliation: Department of Dermatology, University of Virginia, Charlottesville, VA. Electronic address: SG5CH@hscmail.mcc.virginia.edu.
authors.forename: Smitha S
authors.initials: SS
authors.lastname: Kuppalli
mesh_terms: D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000235:genetics; D007889:Leiomyoma / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology; D018231:Leiomyomatosis / Q000175:diagnosis* / Q000235:genetics; D008875:Middle Aged; D009386:Neoplastic Syndromes, Hereditary; D012509:Sarcoma / Q000175:diagnosis* / Q000235:genetics; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000235:genetics; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000235:genetics
keywords: Reed's syndrome; early-onset leiomyomas; fibroids; hereditary leiomyomatosis and renal cell cancer; multiple cutaneous and uterine leiomyomatosis