title: Adult-onset laryngomalacia: case reports and review of management.
abstract: Laryngomalacia is a dynamic airway condition characterised by inward collapse of flaccid supraglottic structures during inspiration. Although the most common cause of stridor in the paediatric population, adult-onset laryngomalacia remains a rare entity and its management, challenging. Two cases of adult-onset laryngomalacia are reported. A review of the English literature is performed and additional publications identified by hand-searching relevant papers; 13 case reports/series comprising 28 cases of adult-onset laryngomalacia were identified, divided into two main groups: idiopathic (6/28) and acquired (22/28). The aetiology of the acquired form includes neurological, traumatic and iatrogenic. Reported therapeutic measures used are laser supraglottoplasty, epiglottopexy, partial epiglottidectomy, defunctioning tracheostomy and intubation whilst correcting the underlying cause. The majority of patients only required one therapeutic procedure (follow-up of 2-24 months). A strong index of suspicion is required to diagnose adult-onset laryngomalacia aided by in-office laryngoscopy. The rarity of this condition prevents management-based randomised controlled trials.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Glasgow Royal Infirmary, NHS Greater Glasgow and Clyde, 84 Castle Street, Glasgow, G4 0SF, UK.
authors.forename: Shi Ying
authors.initials: SY
authors.lastname: Hey
authors.forename: Nashreen Banon
authors.initials: NB
authors.lastname: Oozeer
authors.forename: Stuart
authors.initials: S
authors.lastname: Robertson
authors.forename: Kenneth
authors.initials: K
authors.lastname: MacKenzie
mesh_terms: D019468:Disease Management; D004825:Epiglottis / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D055092:Laryngomalacia / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D058753:Laryngoplasty / Q000379:methods*; D007828:Laryngoscopy / Q000379:methods*; D008875:Middle Aged; D012135:Respiratory Sounds / Q000209:etiology; D014139:Tracheostomy / Q000379:methods*