title: Human palatal and tuberosity mucosa as donor sites for ridge augmentation.
abstract: Since different clinical outcomes of periodontal bilaminar surgeries using the palate or the maxillary tuberosity as connective tissue (CT) donor sites have been observed, tissues grafted with CT from the palate or the tuberosity 1 year after surgical procedures for ridge augmentation were compared with nongrafted tissues by using morphologic and molecular methods. Collagen content and matrix metalloproteinases 1 and 2 expression were similar in tissues and cultured fibroblasts from the palate and tuberosity, although with interindividual differences. In contrast, differences in collagen cross-linking and maturation in the tuberosity fibroblasts were observed, suggesting a possible role in determining hyperplastic responses in some patients.
authors.forename: Claudia
authors.initials: C
authors.lastname: Dellavia
authors.forename: Giano
authors.initials: G
authors.lastname: Ricci
authors.forename: Letizia
authors.initials: L
authors.lastname: Pettinari
authors.forename: Cristina
authors.initials: C
authors.lastname: Allievi
authors.forename: Fabio
authors.initials: F
authors.lastname: Grizzi
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Gagliano
mesh_terms: D000368:Aged; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D002478:Cells, Cultured; D003094:Collagen; D005260:Female; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D020781:Matrix Metalloproteinase 1 / Q000378:metabolism; D020778:Matrix Metalloproteinase 2 / Q000378:metabolism; D008875:Middle Aged; D009061:Mouth Mucosa / Q000637:transplantation*; D010159:Palate / Q000601:surgery*; D055093:Periodontal Atrophy / Q000601:surgery*; D013524:Surgical Flaps; D016896:Treatment Outcome
chemical_list: D003094:Collagen; C522361:MMP2 protein, human; D020778:Matrix Metalloproteinase 2; C522360:MMP1 protein, human; D020781:Matrix Metalloproteinase 1