title: Case for diagnosis. Cutaneous involvement associated to multiple myeloma.
abstract: Cutaneous involvement associated to multiple myeloma varies from 5 to 10% of cases and is infrequently recognized. Cutaneous metastatic plasmacitomas are rare. We present the case of a 72-year-old man with multiple myeloma in complete remission since 2 years ago with cutaneous tumors on the trunk and face. A cutaneous biopsy was consistent with plasmacytoma. The patient was treated with melphalan, prednisolone and radiotherapy. Despite optimal therapeutic response of the lesions, the disease progressed, with the appearance of new extra-cutaneous plasmocytomas. The cutaneous metastatic plasmocytomas were the first sign of progression of the disease.
authors.affiliation: Centro Hospital de Lisboa Central, Santo António dos Capuchos Hospital, Lisbon, Portugal, Dermatology and Venereology Resident at the Santo António dos Capuchos Hospital - Centro Hospital de Lisboa Central (CHLC) - Lisbon, Portugal.
authors.forename: Guida
authors.initials: G
authors.lastname: Santos
authors.affiliation: São Bernardo Hospital, Setúbal, Portugal, Dermatology and Venereology Consultant at the São Bernardo Hospital, Setúbal, Portugal.
authors.forename: Lourdes
authors.initials: L
authors.lastname: Sousa
authors.affiliation: Centro Hospital de Lisboa Central, Santo António dos Capuchos Hospital, Lisbon, Portugal, Consultant of Hematology of the Santo António dos Capuchos Hospital - Centro Hospital de Lisboa Central (CHLC) - Lisbon, Portugal.
authors.forename: Teresa
authors.initials: T
authors.lastname: Fernandes
authors.affiliation: Centro Hospital de Lisboa Central, Santo António dos Capuchos Hospital, Lisbon, Portugal, Dermatology and Venereology Consultant at the Santo António dos Capuchos Hospital - Centro Hospital de Lisboa Central (CHLC) - Lisbon, Portugal.
authors.forename: Alexandre
authors.initials: A
authors.lastname: João
mesh_terms: D000368:Aged; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D018450:Disease Progression; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009101:Multiple Myeloma / Q000473:pathology*; D010954:Plasmacytoma / Q000556:secondary*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000556:secondary*