title: Ovarian endometriomas and oocyte quality: insights from in vitro fertilization cycles.
abstract: OBJECTIVE
  To evaluate whether the presence of endometriomas affects ovarian function.
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  Infertility unit of an academic setting.
  
  
  METHODS
  Twenty-nine women undergoing an IVF cycle.
  
  
  METHODS
  Prospective evaluation of women with unoperated unilateral endometriomas undergoing IVF. The affected and contralateral intact gonads were compared in terms of responsiveness and oocyte quality.
  
  
  METHODS
  Oocyte developmental competence.
  
  
  RESULTS
  Ovarian responsiveness and oocyte quality did not significantly differ between the affected and intact gonads. The number of codominant follicles, the number of oocytes retrieved, and the number of suitable oocytes in affected and intact gonads were 3.7 ± 2.4 and 4.1 ± 1.7, 4.2 ± 3.1 and 4.7 ± 2.5, and 3.1 ± 2.6 and 3.5 ± 2.3, respectively. The number of viable embryos and the number of high-quality embryos were 1.8 ± 2.1 and 1.8 ± 1.4 and 1.0 ± 1.7 and 0.8 ± 0.7, respectively. The fertilization rate in the affected and intact gonads was 64% and 64%, respectively. The cleavage rate was 58% and 51%, respectively. The rate of high-quality embryos was 31% and 21%, respectively.
  
  
  CONCLUSIONS
  In women undergoing IVF, the presence of ovarian endometriomas does not affect oocyte developmental competence.
authors.affiliation: Department of Obstetrics and Gynecology, Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: francesca.filippi@gmail.com.
authors.forename: Francesca
authors.initials: F
authors.lastname: Filippi
authors.affiliation: Department of Obstetrics and Gynecology, Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Benaglia
authors.affiliation: Department of Obstetrics and Gynecology, Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
authors.forename: Alessio
authors.initials: A
authors.lastname: Paffoni
authors.affiliation: Department of Obstetrics and Gynecology, Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
authors.forename: Liliana
authors.initials: L
authors.lastname: Restelli
authors.affiliation: Department of Obstetrics and Gynecology, Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy; Università degli Studi di Milano, Milan, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Vercellini
authors.affiliation: Department of Obstetrics and Gynecology, Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
authors.forename: Edgardo
authors.initials: E
authors.lastname: Somigliana
authors.affiliation: Department of Obstetrics and Gynecology, Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy; Università degli Studi di Milano, Milan, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Fedele
mesh_terms: D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D004715:Endometriosis / Q000473:pathology*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000473:pathology* / Q000628:therapy*; D009865:Oocytes / Q000473:pathology* / Q000637:transplantation*; D010049:Ovarian Diseases / Q000473:pathology*; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D016896:Treatment Outcome; D055815:Young Adult
keywords: Endometrioma; IVF; oocyte