title: Diaphyseal osteosarcoma with varying histomorphologic patterns.
abstract: Osteosarcoma is the most common primary malignant tumor of the skeleton involving predominantly metaphysis of the long bones. Diaphyseal osteosarcoma is a rare form, which accounts for approximately 10% of all cases of osteosarcomas. Osteosarcoma contains a family of lesions with considerable diversity in histologic features and grade. We present a case of a 29-year-old male with diaphyseal osteosarcoma of the left tibia, who presented with pain and swelling over middle one-third of the left leg. The biopsy of the lesion revealed varied histomorphologic features in a small tissue studied. This prompted us to report the various histologic patterns of osteosarcoma.
authors.affiliation: Department of Pathology, Padmashree Dr. DY Patil Medical College, Pune, Maharashtra, India.
authors.forename: Harsh
authors.initials: H
authors.lastname: Kumar
authors.affiliation: Department of Pathology, Padmashree Dr. DY Patil Medical College, Pune, Maharashtra, India.
authors.forename: Archana C
authors.initials: AC
authors.lastname: Buch
authors.affiliation: Department of Pathology, Padmashree Dr. DY Patil Medical College, Pune, Maharashtra, India.
authors.forename: Vinay M
authors.initials: VM
authors.lastname: Sawlani
authors.affiliation: Department of Pathology, Padmashree Dr. DY Patil Medical College, Pune, Maharashtra, India.
authors.forename: Shirish S
authors.initials: SS
authors.lastname: Chandanwale
keywords: Bone tumors; diaphysis; histological pattern; osteosarcoma