title: Multiple upper gastrointestinal perforations in a 15-year-old patient treated with tocilizumab.
authors.affiliation: Department of Pediatric Rheumatology, Department of Pediatric Gastroenterology, Center for Pediatric and Adolescent Medicine and Department of Surgery, Pediatric Surgery Division, University Hospital Heidelberg, Heidelberg, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Pfeil
authors.affiliation: Department of Pediatric Rheumatology, Department of Pediatric Gastroenterology, Center for Pediatric and Adolescent Medicine and Department of Surgery, Pediatric Surgery Division, University Hospital Heidelberg, Heidelberg, Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Grulich-Henn
authors.affiliation: Department of Pediatric Rheumatology, Department of Pediatric Gastroenterology, Center for Pediatric and Adolescent Medicine and Department of Surgery, Pediatric Surgery Division, University Hospital Heidelberg, Heidelberg, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Wenning
authors.affiliation: Department of Pediatric Rheumatology, Department of Pediatric Gastroenterology, Center for Pediatric and Adolescent Medicine and Department of Surgery, Pediatric Surgery Division, University Hospital Heidelberg, Heidelberg, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Breil
authors.affiliation: Department of Pediatric Rheumatology, Department of Pediatric Gastroenterology, Center for Pediatric and Adolescent Medicine and Department of Surgery, Pediatric Surgery Division, University Hospital Heidelberg, Heidelberg, Germany.
authors.forename: Patrick
authors.initials: P
authors.lastname: Günther
authors.affiliation: Department of Pediatric Rheumatology, Department of Pediatric Gastroenterology, Center for Pediatric and Adolescent Medicine and Department of Surgery, Pediatric Surgery Division, University Hospital Heidelberg, Heidelberg, Germany. Thomas.Lutz@med.uni-heidelberg.de.
authors.forename: Thomas
authors.initials: T
authors.lastname: Lutz
mesh_terms: D000293:Adolescent; D061067:Antibodies, Monoclonal, Humanized / Q000009:adverse effects*; D018501:Antirheumatic Agents / Q000009:adverse effects*; D001171:Arthritis, Juvenile / Q000188:drug therapy; D006801:Humans; D007077:Ileal Diseases / Q000139:chemically induced*; D007416:Intestinal Perforation / Q000139:chemically induced*; D008297:Male
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D018501:Antirheumatic Agents; C502936:tocilizumab