title: Influence of obesity on the correlation between laryngopharyngeal reflux and obstructive sleep apnea.
abstract: BACKGROUND
  The obstructive sleep apnea (OSA) is caused by recurrent episodes of partial or total obstruction of the upper airway lasting more than 10 seconds during sleep. Laryngopharyngeal reflux (LPR) is a variant of the disease Gastroesophageal Reflux that affects the larynx and pharynx.
  
  
  OBJECTIVE
  Evaluate the influence of obesity on the relationship between RFL and OSAS in patients with OSA.
  
  
  METHODS
  An observational retrospective cross. We reviewed care protocol for patients with OSA that includes validated questionnaires for RFL as Sympton Reflux Index (RSI) and Reflux Finding Score (RSI), and polysomnography nasolaringofibroscopia.
  
  
  RESULTS
  105 patients were divided into obese group (39 patients) and non-obese patients (66 patients). In the evaluation of the mean RSI group of non-obese was similar between patients with mild OSA (11.96) and moderate (11.43). In the obese group the mean RSI was 6.7 in patients with mild OSA and 11.53 in patients with moderate to severe OSA (p < 0.05).
  
  
  CONCLUSIONS
  The subgroup of patients with OSA and RFL have several factors that promote inflammation of the upper airway. Patients with OSA should be screened and treated as the RFL increasing the quality of life.
  
  
  CONCLUSIONS
  The RFL are positively correlated and OSAS in obese patients.
authors.affiliation: Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, Associação Médica Brasileira (ABORL-CCF/AMB), São Paulo, SP, Brasil.
authors.forename: Marcos Marques
authors.initials: MM
authors.lastname: Rodrigues
authors.affiliation: Universidade de São Paulo, Faculdade de Medicina, Ribeirão PretoSP, Brasil, Faculdade de Medicina, Universidade de São Paulo (USP), Ribeirão Preto, SP, Brasil.
authors.forename: Ralph Silveira
authors.initials: RS
authors.lastname: Dibbern
authors.affiliation: Universidade Estadual Paulista, Faculdade de Medicina, BotucatuSP, Brasil, Faculdade de Medicina, Universidade Estadual Paulista (UNESP), Botucatu, SP, Brasil.
authors.forename: Victor José Barbosa
authors.initials: VJ
authors.lastname: Santos
authors.affiliation: Universidade do Texas, Southwestern Medical Center, DallasTexas, EUA, Southwestern Medical Center, Universidade do Texas, Dallas, Texas, EUA.
authors.forename: Luis Augusto
authors.initials: LA
authors.lastname: Passeri
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D057045:Laryngopharyngeal Reflux / Q000150:complications* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications* / Q000503:physiopathology; D017286:Polysomnography; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000503:physiopathology; D055815:Young Adult