title: Treatment of diabetic foot ulcers using Mepilex Lite Dressings: a pilot study.
abstract: BACKGROUND
  5-10% diabetes patients will develop diabetic foot ulceration at some time during the life. The purpose of this study was to compare the effectiveness of Mepilex Lite dressings and vaseline gauze care in the healing of foot ulcers in diabetic patients.
  
  
  METHODS
  This was a randomized controlled trial, and a sample of 50 diabetic patients who had developed foot ulcers was assessed. Comparisons were made regarding parameters related to wound healing, including healing time and wound pain, and also regarding the adverse events.
  
  
  RESULTS
  The results showed that foot ulcers in the study group (Mepilex Lite, 24 patients) healed in a median of 49.9 days, which was significantly different from the healing time in the control group (median, 65.5 days, 26 patients; P=0.038). No statistically significant differences were detected between the 2 groups with pain. However, Mepilex Lite dressings significantly reduced wound area (P<0.05).
  
  
  CONCLUSIONS
  The researchers conclude that Mepilex Lite dressing provides a promising alternative to diabetic foot ulcers and is worthy of further research.
authors.affiliation: Department of Nutrition, School of Clinical Medicine, Binzhou Medical College, Binzhou, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Oncology, School of Clinical Medicine, Binzhou Medical College, Binzhou, China.
authors.forename: S-Z
authors.initials: SZ
authors.lastname: Xing
mesh_terms: D001458:Bandages; D016022:Case-Control Studies; D017719:Diabetic Foot / Q000628:therapy*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D014945:Wound Healing