title: Clinical recommendation: pediatric lichen sclerosus.
abstract: Lichen sclerosus is a chronic inflammatory condition affecting the anogenital region that may present in the prepubertal or adolescent patient. Clinical presentations include significant pruritus, labial adhesions, and loss of pigmentation. Treatment includes topical anti-inflammatory agents and long-term follow-up as there is a high risk of recurrence and an increased risk of vulvar cancer in adult women with history of lichen sclerosus. These recommendations are intended for pediatricians, gynecologists, nurse practitioners and others who care for pediatric/adolescent girls in order to facilitate diagnosis and treatment.
authors.affiliation: Division of Pediatric and Adolescent Gynecology, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX. Electronic address: jbercaw@bcm.edu.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Bercaw-Pratt
authors.affiliation: Department of Clinical Sciences, University of Central Florida, Orlando, FL.
authors.forename: Lori A
authors.initials: LA
authors.lastname: Boardman
authors.affiliation: Department of Clinical Sciences, University of Central Florida, Orlando, FL.
authors.forename: Judith S
authors.initials: JS
authors.lastname: Simms-Cendan
mesh_terms: D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001624:Betamethasone Valerate / Q000627:therapeutic use; D002648:Child; D002990:Clobetasol / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D018459:Lichen Sclerosus et Atrophicus / Q000175:diagnosis / Q000188:drug therapy*; D012008:Recurrence; D016559:Tacrolimus / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; C117268:pimecrolimus; D001624:Betamethasone Valerate; D002990:Clobetasol; D016559:Tacrolimus
keywords: Adolescent; Pediatric; Vulvar Lichen Sclerosus