title: Tales from a thousand and one phages.
abstract: The sequencing of marine metagenomic fosmids led to the discovery of several new complete phage genomes. Among the 21 major sequence groups, 10 totally novel groups of marine phages could be identified. Some of these represent the first phages infecting large marine prokaryotic phyla, such as the Verrucomicrobia and the recently describedCa.Actinomarinales. Coming from a single deep photic zone sample the diversity of phages found is astonishing, and the comparison with a metavirome from the same location indicates that only 2% of the real diversity was recovered. In addition to this large macro-diversity, rich micro-diversity was also found, affecting host-recognition modules, mirroring the variation of cell surface components in their host marine microbes.
authors.affiliation: Evolutionary Genomics Group; Universidad Miguel Hernandez; Campus de San Juan; Alicante, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Rodriguez-Valera
authors.affiliation: Evolutionary Genomics Group; Universidad Miguel Hernandez; Campus de San Juan; Alicante, Spain.
authors.forename: Carolina Megumi
authors.initials: CM
authors.lastname: Mizuno
authors.affiliation: Evolutionary Genomics Group; Universidad Miguel Hernandez; Campus de San Juan; Alicante, Spain.
authors.forename: Rohit
authors.initials: R
authors.lastname: Ghai
keywords: constant-diversity; deep chlorophyll maximum; marine phages; metagenomics; metavirome; pan-genome; pan-selectome; phage evolution; red-queen