title: Frequency of in-hospital acquired staphylococcus bacteremia/sepsis within ten-year period.
abstract: Analyzing data in the literature, it is noted that in-hospital acquired infections are an increasing problem even in more developed countries. This increasing trend is related to the progress of medical science and introduction of new invasive diagnostic-therapeutic methods, as well as increase of multiresistant types of bacteria, including staphylococci in big percentages.
  
  
  OBJECTIVE
  To analyze frequency of in-hospital acquired staphylococcus bacteremia/sepsis.
  
  
  METHODS
  Anamneses of patients who were diagnosed with staphylococcus bacteremia/sepsis were analyzed within a ten-year period.
  
  
  RESULTS
  Within the analyzed period from 2001 to 2011, there were 87 patients with diagnosis of staphylococcus bacteremia/sepsis, out of which (20) 77% were diagnosed with sepsis, and (67) 23% with bacteremia. In-hospital outcome was present with 32 (36.8%) patients, while 55 (63.2%) were out of hospital. The chi-square test for independence showed that the diagnosis of bacteremia/sepsis and the place of the infection origin (in hospital/ out of hospital) were independent chi2 = 1.951 df= 1 p=0.162. The cause isolated from hemoculture depends on the place of the infection origin (out of hospital/in hospital); larger percentage of methicillin-resistant types was presented in in-hospital acquired infections chi2 11.352 df=1 p=0.001. And the chi-square test for independence showed both dependence of the preceding antibiotic treatment and the place of the infection origin in both categories of patients. Sepsis: chi2 = 22.92 df=1 p<0.0005; Bacteremia: chi2 = 9.89 df=1 p= 0.005.
  
  
  CONCLUSIONS
  The results showed larger percentage of methicillin-resistant types in in-hospital acquired infections, as well as significantly larger percentage of hospital infections with the preceding antibiotic therapy, which puts in focus possible rationalization of including antibiotic therapy.
authors.affiliation: Department of Epidemiology, Clinical Centre University of Sarajevo, Bosnia and Herzegovina. rbaljic@gmail.com
authors.forename: Aida
authors.initials: A
authors.lastname: Pitic
authors.affiliation: Clinic for Infectious diseases, Clinical Centre University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
authors.forename: Enra
authors.initials: E
authors.lastname: Lukovac
authors.affiliation: Clinic for Infectious diseases, Clinical Centre University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
authors.forename: Nada
authors.initials: N
authors.lastname: Koluder
authors.affiliation: Clinic for Infectious diseases, Clinical Centre University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
authors.forename: Rusmir
authors.initials: R
authors.lastname: Baljic
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology; D017522:Bosnia and Herzegovina / Q000453:epidemiology; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification; D018805:Sepsis / Q000453:epidemiology / Q000382:microbiology; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013212:Staphylococcus epidermidis / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents