title: Risk factors for candidemia in pediatric intensive care unit patients.
abstract: OBJECTIVE
  To determine the risk factors for developing candida infections in pediatric intensive care unit (PICU).
  
  
  METHODS
  The present study was conducted as a case-control study and included the population of patients who were admitted to PICU during the period of March 2010-March 2011.
  
  
  RESULTS
  During the study period, a total of 57 patients in PICU had candidemia, 4 cases were excluded due to their PICU stay less than 48 h and one due to the insufficient data. The most commonly isolated Candida species was C. albicans, followed by C. parapsilosis. The median duration of hospitalization in PICU was higher (22.0 d) in candidemia patients compared to control group (13.5 d) (p = 0.037). The patients with candidemia had higher rates of presence of mechanical ventilation, presence of central venous catheter, and being under total parenteral nutrition; compared to the control group.
  
  
  CONCLUSIONS
  The longer PICU durations, mechanical ventilation, central venous catheter, total parenteral nutrition were the associated factors. Although trials for predicitive models or scoring systems for development of candidemia have been performed; more future studies were required for practical usage in clinics settings in order to prevent candidemia.
authors.affiliation: Department of Intensıve Care, Dr. Behcet Uz Children's Hospital, Izmir, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Ağın
authors.forename: Ilker
authors.initials: I
authors.lastname: Devrim
authors.forename: Rana
authors.initials: R
authors.lastname: Işgüder
authors.forename: Utku
authors.initials: U
authors.lastname: Karaarslan
authors.forename: Esra
authors.initials: E
authors.lastname: Kanık
authors.forename: Ilker
authors.initials: I
authors.lastname: Günay
authors.forename: Miray
authors.initials: M
authors.lastname: Kışla
authors.forename: Sultan
authors.initials: S
authors.lastname: Aydın
authors.forename: Gamze
authors.initials: G
authors.lastname: Gülfidan
mesh_terms: D058387:Candidemia / Q000453:epidemiology* / Q000382:microbiology; D016022:Case-Control Studies; D002405:Catheterization, Central Venous / Q000009:adverse effects; D002648:Child; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D015278:Intensive Care Units, Pediatric; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D010289:Parenteral Nutrition, Total / Q000009:adverse effects; D012121:Respiration, Artificial / Q000009:adverse effects; D012189:Retrospective Studies; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology