title: [Donepezil therapy by neuropathic pain].
abstract: A case report of a successful treatment of neuropathic pain after a plexus brachialis injury is presented. On basis of experience from nerve-injured rat models 5 mg donepezil was added to an already instituted gabapentin therapy of 800 mg x 3 daily. This allowed halving the gapentin dose with fully contained pain alleviation but with a drastic reduction of gabapentin's side effects: ataxia and somnolence. Thus, without adding any new side effects life quality was improved and an increased working capacity was observed together with a weight loss of 9 kg over six months.
authors.affiliation: Gartnerkrogen 59, 3500 Værløse. ojb@farma.ku.dk.
authors.forename: Ole J
authors.initials: OJ
authors.lastname: Bjerrum
authors.forename: Hans J
authors.initials: HJ
authors.lastname: Bjerrum
mesh_terms: D000368:Aged; D000700:Analgesics / Q000627:therapeutic use*; D000077265:Donepezil; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007189:Indans / Q000627:therapeutic use*; D009437:Neuralgia / Q000188:drug therapy*; D010880:Piperidines / Q000627:therapeutic use*; D020069:Shoulder Pain / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000700:Analgesics; D007189:Indans; D010880:Piperidines; D000077265:Donepezil