title: The relationship between impulsivity and lipid levels in bipolar patients: does temperament explain it?
abstract: BACKGROUND
  The aim of this study was to investigate whether there was a relationship between impulsivity and lipid levels in patients with bipolar disorder (BD) and to examine the correlation of impulsivity and lipid levels with temperament subtypes.
  
  
  METHODS
  For this purpose, one hundred patients who were admitted to our out-patient unit for routine controls, had been in remission for at least 8weeks, and diagnosed as BD according to the DSM-IV were evaluated consecutively. Impulsivity and temperament were evaluated with the BIS-11 and the TEMPS-A. Blood samples were obtained to measure levels of lipids (cholesterol, triglyceride, high density lipoprotein-HDL, low density lipoprotein-LDL).
  
  
  RESULTS
  A weak correlation was found between impulsivity scores and triglyceride levels (r=0.190, p=0.050). Correlation was found between impulsivity scores and depressive, anxious, cyclothymic, and irritable temperaments (r=0.371, p<0.001; r=0.458, p<0.001; r=0.541, p<0.001; r=0.530, p<0.001), while triglyceride levels were only related with depressive and anxious temperaments (r=0.485, p=0.001 and r=0.391, p=0.006).
  
  
  CONCLUSIONS
  Temperament is an important mediator of the relationship between lipid levels and trait impulsivity in patients with BD.
authors.affiliation: Erenköy Mental and Neurological Disease Training and Research Hospital, Department of Psychiatry Istanbul, Turkey. Electronic address: eliftatlidil@yahoo.com.
authors.forename: Elif
authors.initials: E
authors.lastname: Tatlidil Yaylaci
authors.affiliation: Erenköy Mental and Neurological Disease Training and Research Hospital, Department of Psychiatry Istanbul, Turkey.
authors.forename: Sermin
authors.initials: S
authors.lastname: Kesebir
authors.affiliation: Erenköy Mental and Neurological Disease Training and Research Hospital, Department of Psychiatry Istanbul, Turkey.
authors.forename: Özlem
authors.initials: Ö
authors.lastname: Güngördü
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000097:blood / Q000175:diagnosis / Q000523:psychology; D001714:Bipolar Disorder / Q000097:blood* / Q000175:diagnosis / Q000523:psychology*; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000097:blood* / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory / Q000706:statistics & numerical data; D011594:Psychometrics; D013223:Statistics as Topic; D013694:Temperament; D014421:Turkey
chemical_list: D008055:Lipids