title: Breast cancer in Morocco: a literature review.
abstract: In Morocco, breast cancer is the most prevalent cancer in women and a major public health problem. Several Moroccan studies have focused on studying this disease, but more are needed, especially at the genetic and molecular levels. It is therefore interesting to establish the genetic and molecular profile of Moroccan patients with breast cancer. In this paper, we will highlight some pertinent hypotheses that may enhance breast cancer care in Moroccan patients. This review will give a precise description of breast cancer in Morocco and propose some new markers for detection and prediction of breast cancer prognosis.
authors.affiliation: Equipe de Recherche ONCOGYMA, Universite Mohamed V-Souissi Faculty of Medicine and Pharmacy of Rabat, Rabat, Morocco E-mail : m.amrani@um5s.net.ma, am13ca13@yahoo.fr.
authors.forename: Meriem
authors.initials: M
authors.lastname: Slaoui
authors.forename: Rachid
authors.initials: R
authors.lastname: Razine
authors.forename: Azeddine
authors.initials: A
authors.lastname: Ibrahimi
authors.forename: Mohammed
authors.initials: M
authors.lastname: Attaleb
authors.forename: Mohammed El
authors.initials: ME
authors.lastname: Mzibri
authors.forename: Mariam
authors.initials: M
authors.lastname: Amrani
mesh_terms: D019313:BRCA1 Protein / Q000235:genetics; D024682:BRCA2 Protein / Q000235:genetics; D014408:Biomarkers, Tumor / Q000235:genetics / Q000276:immunology; D018567:Breast Neoplasms, Male / Q000453:epidemiology / Q000235:genetics / Q000401:mortality / Q000628:therapy; D018572:Disease-Free Survival; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D018960:Hyaluronan Receptors / Q000235:genetics / Q000276:immunology; D058922:Inflammatory Breast Neoplasms / Q000453:epidemiology / Q000235:genetics / Q000401:mortality / Q000628:therapy; D008297:Male; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics; D009018:Morocco / Q000453:epidemiology; D018396:Mucin-1 / Q000235:genetics; D064726:Triple Negative Breast Neoplasms / Q000453:epidemiology / Q000235:genetics / Q000401:mortality / Q000628:therapy; D020741:rho GTP-Binding Proteins / Q000235:genetics; D000075024:rhoC GTP-Binding Protein
chemical_list: D019313:BRCA1 Protein; C492913:BRCA1 protein, human; D024682:BRCA2 Protein; C551750:BRCA2 protein, human; D014408:Biomarkers, Tumor; C497483:CD44 protein, human; D018960:Hyaluronan Receptors; C060192:MUC1 protein, human; D018396:Mucin-1; D042965:Methylenetetrahydrofolate Reductase (NADPH2); C066690:RHOC protein, human; D020741:rho GTP-Binding Proteins; D000075024:rhoC GTP-Binding Protein