title: Imaging diagnosis of neonatal anemia: report of two unusual etiologies.
abstract: Anemia in neonatal period is rare, with the common causes being Rh and ABO blood group incompatibility, hemorrhagic disease of newborn, congenital hemolytic anemia, hemoglobinopathies, and TORCH (toxoplasmosis, rubella, cytomegalovirus, herpes virus) infections. Congenital leukemia and infantile osteopetrosis (OP) are among the rare causes of neonatal anemia. A review of the literature shows approximately 200 reported cases of congenital leukemia. Articles describing the imaging features of congenital leukemia are still rarer. Infantile OP, another rare disorder with a reported incidence of 1 in 250,000 has characteristic imaging features, which are diagnostic of the disease. We report a case each, of two rare diseases: Congenital leukemia and infantile osteopetrosis. Additionally, our report highlights the radiological and imaging features of congenital leukemia and infantile OP and their crucial role in arriving at an early diagnosis.
authors.affiliation: Department of Radiodiagnosis and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
authors.forename: Shabnam Bhandari
authors.initials: SB
authors.lastname: Grover
authors.affiliation: Department of Radiodiagnosis and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
authors.forename: G Rajalakshmi
authors.initials: GR
authors.lastname: Preethi
authors.affiliation: Department of Hematology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
authors.forename: Sumita
authors.initials: S
authors.lastname: Saluja
authors.affiliation: Department of Radiodiagnosis and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
authors.forename: Ankit
authors.initials: A
authors.lastname: Bhargava
keywords: Congenital leukemia; infantile osteopetrosis; neonatal anemia; radiological and imaging features