title: High prevalence and no latitude gradient of multiple sclerosis in Norway.
abstract: The prevalence of multiple sclerosis (MS) is increasing, and the presence of a latitude gradient for MS risk is still discussed. We present the first nationwide prevalence estimates for Norway, spanning the latitudes from 58-71 degrees North, in order to identify a possible latitude gradient. Information from the Oslo MS Registry and the Norwegian MS Registry and Biobank was combined with data from the Norwegian Patient Registry, the Norwegian Prescription Database and Statistics Norway. We estimated a crude prevalence of 203/100,000 on 1 January 2012. The prevalence in the Northern and Southern regions were not significantly different. MS prevalence in Norway is among the highest reported worldwide. We found no evidence of a latitude gradient.
authors.affiliation: Department of Neurology, Oslo University Hospital, Ullevål and Institute of Clinical Medicine, University of Oslo, Norway pberghansen@gmail.com.
authors.forename: P
authors.initials: P
authors.lastname: Berg-Hansen
authors.affiliation: Department of Neurology, Oslo University Hospital, Ullevål and Institute of Clinical Medicine, University of Oslo, Norway.
authors.forename: S M
authors.initials: SM
authors.lastname: Moen
authors.affiliation: Department of Neurology, Oslo University Hospital, Ullevål and Institute of Clinical Medicine, University of Oslo, Norway.
authors.forename: H F
authors.initials: HF
authors.lastname: Harbo
authors.affiliation: Department of Neurology, Oslo University Hospital, Ullevål and Institute of Clinical Medicine, University of Oslo, Norway.
authors.forename: E G
authors.initials: EG
authors.lastname: Celius
mesh_terms: D006801:Humans; D009103:Multiple Sclerosis / Q000453:epidemiology*; D009664:Norway / Q000453:epidemiology; D015995:Prevalence; D012042:Registries
keywords: Epidemiology; Norway; latitude; latitude gradient; multiple sclerosis; prevalence