title: [Acute toxic dystrophy of the liver during antituberculosis therapy].
abstract: The paper considers a case of acute toxic dystrophy of the liver developing as a manifestation of an idiosyncratic dose-independent unpredictable reaction during standard antituberculosis therapy. The process of liver damage was fulminant with massive diffuse centrilobular necroses, lymphoid-eosinophilic infiltration in the portal tracts, and the development of liver failure.
authors.forename: Iu R
authors.initials: IuR
authors.lastname: Ziuzia
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Parkhomenko
authors.forename: O A
authors.initials: OA
authors.lastname: Tishkevich
mesh_terms: D000995:Antitubercular Agents / Q000008:administration & dosage / Q000633:toxicity*; D001344:Autopsy; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000401:mortality / Q000473:pathology* / Q000821:virology; D003933:Diagnosis; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis* / Q000401:mortality / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D014376:Tuberculosis / Q000188:drug therapy* / Q000401:mortality / Q000821:virology
chemical_list: D000995:Antitubercular Agents