title: Management of accidental exposure to HIV: the COREVIH 2011 activity report.
abstract: BACKGROUND
  Post-exposure prophylaxis (PEP) relies on procedures allowing quick access to treatment in case of accidental exposure to viral risk (AEV). Occupational blood exposure (OBE) affects mainly caregivers; these accidents are monitored and assessed by the inter-regional center for nosocomial infections (C-CLIN), occupational physicians, and infection control units. They are classified apart from sexual exposure for which there is currently no monitoring.
  
  
  METHODS
  Data was extracted from the COREVIH (steering committee for the prevention of HIV infection) 2011 activity reports (AR), available online. Data collection was performed using a standardized grid.
  
  
  RESULTS
  Twenty-four out of 28 AR were available online. Nine thousand nine hundred and twenty AEV were reported, 44% of OBE, and 56% of sexual and other exposures. PEP was prescribed in 8% of OBE and in 77% of sexual exposures. The type of PEP was documented in 52% of the cases. Follow-up was poorly documented.
  
  
  CONCLUSIONS
  AR provide an incomplete and heterogeneous review of exposure management without any standardized data collection. The difficulties encountered in data collection and monitoring are due to differences in care centers (complex patient circuits, multiple actors) and lack of common dedicated software. Sexual exposures account for 50% of AEV and most are treated; but they are incompletely reported and consequently not analyzed at the regional or national level. A typical AR collection grid is being studied in 2 COREVIH, with the objective to improve collection and obtain useful national data.
authors.affiliation: Groupe d'étude sur le risque d'exposition des soignants aux agents infectieux (GERES), UFR de médecine Bichat, 16, rue Henri-Huchard, 75018 Paris, France; COREVIH Île-de-France Ouest, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92104 Boulogne-Billancourt, France.
authors.forename: E
authors.initials: E
authors.lastname: Rouveix
authors.affiliation: Groupe d'étude sur le risque d'exposition des soignants aux agents infectieux (GERES), UFR de médecine Bichat, 16, rue Henri-Huchard, 75018 Paris, France; COREVIH Île-de-France Nord, hôpital Bichat - Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Bouvet
authors.affiliation: COREVIH Île-de-France Ouest, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92104 Boulogne-Billancourt, France.
authors.forename: F
authors.initials: F
authors.lastname: Vernat
authors.affiliation: COREVIH Île-de-France Nord, hôpital Bichat - Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Chansombat
authors.affiliation: COREVIH Île-de-France Nord, hôpital Bichat - Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France.
authors.forename: G
authors.initials: G
authors.lastname: Hamet
authors.affiliation: Groupe d'étude sur le risque d'exposition des soignants aux agents infectieux (GERES), UFR de médecine Bichat, 16, rue Henri-Huchard, 75018 Paris, France. Electronic address: gerard.pellissier@geres.org.
authors.forename: G
authors.initials: G
authors.lastname: Pellissier
mesh_terms: D000062:Accidents, Occupational / Q000706:statistics & numerical data; D000359:Aftercare / Q000706:statistics & numerical data; D000847:Annual Reports as Topic; D019380:Anti-HIV Agents / Q000627:therapeutic use; D017848:Blood-Borne Pathogens; D003428:Cross Infection / Q000517:prevention & control / Q000635:transmission; D003625:Data Collection; D019468:Disease Management; D004363:Drug Utilization; D005568:Forms and Records Control; D005602:France / Q000453:epidemiology; D006077:Government Agencies / Q000458:organization & administration* / Q000706:statistics & numerical data; D015658:HIV Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission; D006679:HIV Seropositivity; D006282:Health Personnel / Q000706:statistics & numerical data; D006297:Health Services Accessibility; D006801:Humans; D017053:Infection Control / Q000458:organization & administration* / Q000706:statistics & numerical data; D016273:Occupational Exposure; D056990:Post-Exposure Prophylaxis / Q000379:methods / Q000458:organization & administration* / Q000706:statistics & numerical data; D012017:Referral and Consultation / Q000706:statistics & numerical data; D012725:Sexual Behavior
chemical_list: D019380:Anti-HIV Agents
keywords: Accident d’exposition aux liquides biologiques; COREVIH; Exposure to body fluids; Post-exposure prophylaxis; Traitement post-exposition