title: Pelopuradazole, a new imidazole derivative alkaloid from the marine bacteria Pelomonas puraquae sp. nov.
abstract: One new imidazole derivative alkaloid pelopuradazole (1), together with three known alkaloids as in 3H-imidazole-4-carboxylic acid (2), 1H-pyrrole-2-carboxylic acid (3) and 2-methyl-3H-imidazole-4-carboxylic acid (4) and two known cyclo-dipeptides pelopurin A (5) and pelopurin B (6), has been isolated from the marine bacterium Pelomonas puraquae sp. nov. Pelopuradazole (1) was a new imidazole derivative alkaloid, while compounds 2, 3, 5 and 6 were firstly obtained as natural products. Compounds 1-6 were isolated from P. puraquae sp. nov. for the first time.
authors.affiliation: a School of Chinese Materia Medica, Guangzhou University of Chinese Medicine , 232 Waihuan East Road, Guangzhou 510006 , P.R. China.
authors.forename: Xi-Xin
authors.initials: XX
authors.lastname: He
authors.forename: Xiao-Jie
authors.initials: XJ
authors.lastname: Chen
authors.forename: Guang-Tian
authors.initials: GT
authors.lastname: Peng
authors.forename: Shan-Yue
authors.initials: SY
authors.lastname: Guan
authors.forename: Ling-Fang
authors.initials: LF
authors.lastname: Lei
authors.forename: Jun-Hua
authors.initials: JH
authors.lastname: Yao
authors.forename: Bing-Xin
authors.initials: BX
authors.lastname: Liu
authors.forename: Cui-Xian
authors.initials: CX
authors.lastname: Zhang
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D042621:Comamonadaceae / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry / Q000302:isolation & purification*; D008386:Marine Biology; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification; D011392:Proline / Q000031:analogs & derivatives / Q000302:isolation & purification
chemical_list: D000470:Alkaloids; D007093:Imidazoles; D010456:Peptides, Cyclic; C000591777:pelopuradazole; C002986:2-pyrrolecarboxylic acid; D011392:Proline
keywords: Pelomonas puraquae sp. nov.; Pelopuradazole; alkaloid; cyclic dipeptide; marine bacteria