title: Chronotropic incompetence precedes silent pulmonary embolism.
abstract: A patient with recurrent pulmonary emboli collected heart rate data during exercise, which provided important premorbid clues to changes in cardiopulmonary exercise tolerance coincident with accrual of thrombus in the central circulation. On both occasions, chronotropic incompetence (CI) preceded the pulmonary emboli events. When patients with programmed exercise goals notice CI, they should seek professional guidance.
authors.affiliation: 2Department of Pathology, University of Virginia School of Medicine and Medical Laboratories, University of Virginia Health System, Charlottesville, VA; 3Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA; 1School of Engineering and Applied Science, University of Virginia, Charlottesville, VA.
authors.forename: Karunasai
authors.initials: K
authors.lastname: Mahadevan
authors.forename: Lawrence M
authors.initials: LM
authors.lastname: Silverman
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Becker
mesh_terms: D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D018670:Monitoring, Ambulatory / Q000379:methods*; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000503:physiopathology*