title: In vivo biocompatibility versus degree of conversion of resin-reinforced cements in different time periods.
abstract: This study focused on test the null hypothesis that there is no difference between the degree of conversion and biocompatibility of different resin reinforced glass ionomer cements (RRGICs). Forty-eight male Wistar rats were used, distributed into four groups (n = 12), as follows: Group C (Control, polyethylene), Group FOB (Fuji Ortho Band), Group UBL (Ultra band Lok), and Group MCG (Multicure Glass), in subcutaneous tissue. The events of edema, necrosis, granulation tissue, multinuclear giant cells, young fibroblasts, and collagen formation were analyzed at 7, 15, and 30 days. The degree of conversion was evaluated by the Fourier method. Biocompatibility and degree of conversion were assessed using the Kruskal-Wallis and Dunn tests, and ANOVA and Tukey's test, respectively (P < 0.05). It was observed that, there was significant difference between Groups FOB and UBL for the presence of young fibroblasts at 15 days (P = 0.034) and between the Control and MCG Groups for the presence of multinucleated giant cells at 30 days (P = 0.009). Monomer conversion increased progressively until day 30, with significant difference between Group FOB and Groups UBL and MCG (P = 0.013) at 15 days. The null hypothesis was partially accepted, Fuji Ortho Band showed a less monomer conversion and a smaller number of young fibroblasts in the time of 15 days.
authors.affiliation: Department of Orthodontics and Clinic, Federal University of Campina Grande, Paraíba, Brazil, Av. dos Universitários, s/n, Rodovia Patos/Teixeira, Km1, Santa Cecília, CEP, 58700-970.
authors.forename: Rogério
authors.initials: R
authors.lastname: Lacerda-Santos
authors.forename: Maria Isabel Serpa Simões
authors.initials: MI
authors.lastname: De Farias
authors.forename: Fabiola Galbiatti
authors.initials: FG
authors.lastname: De Carvalho
authors.forename: Matheus Melo
authors.initials: MM
authors.lastname: Pithon
authors.forename: Pollianna Muniz
authors.initials: PM
authors.lastname: Alves
authors.forename: Orlando Motohiro
authors.initials: OM
authors.lastname: Tanaka
authors.forename: Gymenna Maria Tenório
authors.initials: GM
authors.lastname: Guênes
mesh_terms: D000180:Acrylic Resins / Q000009:adverse effects / Q000378:metabolism; D000538:Aluminum Silicates / Q000009:adverse effects / Q000378:metabolism; D000818:Animals; D004487:Edema / Q000139:chemically induced; D005347:Fibroblasts / Q000378:metabolism; D015726:Giant Cells / Q000378:metabolism; D005899:Glass Ionomer Cements / Q000009:adverse effects / Q000378:metabolism*; D007249:Inflammation / Q000139:chemically induced; D008297:Male; D008422:Materials Testing / Q000379:methods; D009336:Necrosis / Q000139:chemically induced; D017208:Rats, Wistar; D019279:Resin Cements / Q000009:adverse effects / Q000378:metabolism*; D013997:Time Factors
chemical_list: D000180:Acrylic Resins; D000538:Aluminum Silicates; C112133:Fuji Ortho; D005899:Glass Ionomer Cements; D019279:Resin Cements; C508229:Ultra Band-Lok
keywords: biocompatibility; glass ionomer cements; orthodontics