title: Metal-triflate-catalyzed synthesis of polycyclic tertiary alcohols by cyclization of γ-allenic ketones.
abstract: It has been established that bismuth(III) triflate catalyzes the cyclization of γ-allenic ketones under mild reaction conditions. This reaction allows the selective formation of polycyclic tertiary alcohols from cyclic ketone derivatives. The resulting dienols can engage in stereoselective cycloadditions to efficiently afford complex polycyclic systems.
authors.affiliation: Institut de Chimie de Nice UMR 7272, Université de Nice Sophia-Antipolis, CNRS, Parc Valrose, 06108 Nice Cedex 2 (France).
authors.forename: Ilhem
authors.initials: I
authors.lastname: Diaf
authors.forename: Gilles
authors.initials: G
authors.lastname: Lemière
authors.forename: Elisabet
authors.initials: E
authors.lastname: Duñach
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis*; D000466:Alkadienes / Q000737:chemistry*; D001729:Bismuth / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007659:Ketones / Q000138:chemical synthesis; D015394:Molecular Structure
chemical_list: D000438:Alcohols; D000466:Alkadienes; D007659:Ketones; C025947:propadiene; D001729:Bismuth
keywords: allenes; bismuth; cyclizations; homogeneous catalysis; synthetic methods