title: In vitro apatite formation on porous anodic alumina induced by a phosphorylation treatment.
abstract: In this study, a phosphorylation treatment of porous anodic alumina (PAA) was performed by wet impregnation in phosphoric acid and a subsequent heat treatment. The PAA and phosphorylated PAA specimens were analyzed using a field emission scanning electron microscope, an energy-dispersive X-ray spectrometer, and Fourier transform infrared spectroscopy. The apatite-forming ability of the phosphorylated PAA was evaluated by soaking the specimens in simulated body fluid for 1, 3, and 7 days. The surface microstructures and chemical property changes after soaking in simulated body fluid were again characterized by field emission scanning electron microscope, energy-dispersive X-ray spectrometer, and Fourier transform infrared spectroscopy. Results of this study demonstrated that the functional -PO4 groups introduced onto the PAA surface dramatically promoted the deposition of bone-like apatite on PAA. The results from this study indicated that the phosphorylation treatment of anodic alumina is an effective method for inducing bone-like apatite formation, and this phosphorylated PAA can be a promising candidate to be used as bioactive surface coatings on implant metals and alloys for orthopedic and dental applications.
authors.affiliation: College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, P. R. China.
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Li
authors.affiliation: College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, P. R. China Department of Chemical Engineering, College of Engineering, Northeastern University, Boston, MA, USA synicn@dhu.edu.cn.
authors.forename: Siyu
authors.initials: S
authors.lastname: Ni
authors.affiliation: Department of Chemical Engineering, College of Engineering, Northeastern University, Boston, MA, USA Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi Arabia.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Webster
mesh_terms: D000537:Aluminum Oxide / Q000737:chemistry*; D001031:Apatites / Q000138:chemical synthesis*; D004566:Electrodes; D066298:In Vitro Techniques; D008855:Microscopy, Electron, Scanning; D010766:Phosphorylation; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D001031:Apatites; D000537:Aluminum Oxide
keywords: Porous anodic alumina; bioactive; bone-like apatite; functional groups; phosphorylation treatment