title: A clinical study to evaluate the efficacy of intravitreal Anti-VEGF therapy in treating macular edema due to retinal venous occlusions.
abstract: BACKGROUND
  A non-randomized, interventional study was carried out various types of retinal venous occlusions with significant macular edema who required an Anti-VEGF injection.
  
  
  METHODS
  One hundred and one consecutive patients diagnosed as a case of CRVO/HCRVO/BRVO were enrolled in the study provided they had significant macular edema. Atleast three intra-vitreal injections of Anti-VEGFs were given and both the pre and post injections BCVA and CMT on OCT were observed and analyzed.
  
  
  RESULTS
  87 patients (86.14%) showed a significant improvement of vision of atleast two lines on the Snellen's and mean BCVA improved from log MAR +1.084 to log MAR +0.455. CMT on OCT showed reduction in thickness after Anti-VEGF therapy in 99 patients out of 101 and mean CMT decreased from 586.30 μ at baseline to 329.50 μ. Both of these findings were statistically very significant.
  
  
  CONCLUSIONS
  Anti-VEGF therapy had a marked improvement in BCVA along with a dramatic reduction in CMT in the vast majority of RVOs patients with no serious ocular or systemic side effects.
authors.affiliation: Associate Professor, Department of Ophthalmology, Armed Forces Medical College, Pune 40, India.
authors.forename: Poninder
authors.initials: P
authors.lastname: Kumar
authors.affiliation: Commandant, Military Hospital Secunderabad, Andhra Pradesh, India.
authors.forename: Ajay
authors.initials: A
authors.lastname: Banarji
authors.affiliation: Commandant, 153 General Hospital, C/O -56 APO, India.
authors.forename: Sagarika
authors.initials: S
authors.lastname: Patyal
authors.affiliation: Consultant (Ophthalmology), Command Hospital (Eastern Command), Kolkatta, India.
authors.forename: V S
authors.initials: VS
authors.lastname: Gurunadh
authors.affiliation: Professor & Head, Department of Ophthalmology, Armed Forces Medical College, Pune 40, India.
authors.forename: T S
authors.initials: TS
authors.lastname: Ahluwalia
authors.affiliation: Graded Specialist (Ophthalmology), Command Hospital (Air Force), Bangalore, India.
authors.forename: Avadesh
authors.initials: A
authors.lastname: Oli
authors.affiliation: Associate Professor, Department of Ophthalmology, Armed Forces Medical College, Pune 40, India.
authors.forename: P S
authors.initials: PS
authors.lastname: Moulick
authors.affiliation: Professor (Microbiology), ACMS, Delhi, India.
authors.forename: Anuradha
authors.initials: A
authors.lastname: Makker
keywords: Anti-VEGFs; BCVA; CMT; Macular edema; RVOs