title: Continuous photochemical cleavage of linkers for solid-phase synthesis.
abstract: Photolabile linkers are an attractive alternative for solid-phase synthesis because they can be cleaved using light. However, irradiation in a classical batch photoreactor results in incomplete cleavage of the photolabile linkers. It is demonstrated that a continuous flow photoreactor is superior to a batch photoreactor for the cleavage of a linker from polystyrene resin.
authors.affiliation: Max Planck Institute of Colloids and Interfaces Am Mühlenberg 1, 14476 Potsdam Germany.
authors.forename: Mattan
authors.initials: M
authors.lastname: Hurevich
authors.forename: Jeyakumar
authors.initials: J
authors.lastname: Kandasamy
authors.forename: Bopanna M
authors.initials: BM
authors.lastname: Ponnappa
authors.forename: Mayeul
authors.initials: M
authors.lastname: Collot
authors.forename: Daniel
authors.initials: D
authors.lastname: Kopetzki
authors.forename: D Tyler
authors.initials: DT
authors.lastname: McQuade
authors.forename: Peter H
authors.initials: PH
authors.lastname: Seeberger