title: [The brand new trend of colorectal carcinoma pathology].
abstract: Japanese classification of colorectal carcinoma continues to develop several decades. In 2015, the Japanese Society for Cancer of the Colon and Rectum published the eighth edition of the general rules for clinical and pathological studies on cancer of the colon, rectum, and anus. The new Japanese classification of colorectal carcinoma based on new evidences including sessile serrated adenoma/polyp (SSA/P) of serrated polyp, budding, desmoplastic reaction, head/stalk invasion, submucosal invasion depth for early cancer, EX (extramural cancer deposit), and PN (perineural invasion) for advanced cancer. And recently molecular targeted therapy for anti EGFR has made rapidly progress in refractory advanced cancer. However, some issues still remain to be resolved in pathological diagnosis. We describe and discuss about assessment of pathological diagnosis for new therapy for colorectal carcinoma.
authors.affiliation: Department of Surgical and Molecular Pathology, Dokkyo Medical University School of Medicine.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Tomita
authors.affiliation: Department of Surgical and Molecular Pathology, Dokkyo Medical University School of Medicine.
authors.forename: Mayuko
authors.initials: M
authors.lastname: Yamauchi
authors.affiliation: Department of Surgical and Molecular Pathology, Dokkyo Medical University School of Medicine.
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Ichikawa
authors.affiliation: Department of Surgical and Molecular Pathology, Dokkyo Medical University School of Medicine.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Mitomi
authors.affiliation: Department of Surgical and Molecular Pathology, Dokkyo Medical University School of Medicine.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Fujimori
mesh_terms: D015179:Colorectal Neoplasms / Q000473:pathology* / Q000628:therapy; D006801:Humans; D058990:Molecular Targeted Therapy