title: Description of a new experimental model skin flap for studying skin viability in rats.
abstract: OBJECTIVE
  To describe a new experimental flap for studying skin viability in rats.
  
  
  METHODS
  Twenty male Wistar rats weighing between 250-300g were divided into two groups: group A - McFarlane technique, a 4 x 10cm flap was used (McFarlane); and in group B modified McFarlane technique, a 3 x 10cm flap was used. Seven days later, the animals were sacrificed and the area of necrosis was evaluated in both groups.
  
  
  RESULTS
  Group A presented necrosis in 3% of the total area of the flap (CI: 0.01-0.05), Group B presented necrosis in 37% of the total area of the flap (CI: 0.29-0.46), (p<0.001).
  
  
  CONCLUSIONS
  The modified McFarlane flap presented a larger area of necrosis and could be an adequate experimental model of skin flap viability.
authors.affiliation: University of Sao Paulo, School of Medicine, Sao PauloSP, Brazil, Fellow PhD degree, Postgraduate Program in Medicine Surgical Clinics, School of Medicine, University of Sao Paulo (USP), Sao Paulo-SP, Brazil. Surgical procedures, acquisition of data, manuscript writing.
authors.forename: Cristina Pires
authors.initials: CP
authors.lastname: Camargo
authors.affiliation: USP, School of Medicine, Department of Anatomy, Sao PauloSP, Brazil, Emeritus Professor, Department of Anatomy, School of Medicine, USP, Sao Paulo-SP, Brazil. Critical revision.
authors.forename: Nelson Fontana
authors.initials: NF
authors.lastname: Margarido
authors.affiliation: USP, School of Medicine, Sao PauloSP, Brazil, Graduate student, School of Medicine, USP, Sao Paulo-SP, Brazil. Surgical procedures.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Guandelini
authors.affiliation: USP, School of Medicine, Sao PauloSP, Brazil, Graduate student, School of Medicine, USP, Sao Paulo-SP, Brazil. Surgical procedures.
authors.forename: Guilherme Alexandre Barrucci
authors.initials: GA
authors.lastname: Vieira
authors.affiliation: USP, School of Medicine, Department of Surgery, Sao PauloSP, Brazil, Associate Professor, Descriptive and Topographic Anatomy Division, Department of Surgery, School of Medicine, USP, Sao Paulo-SP, Brazil. Manuscript writing, critical revision.
authors.forename: Alfredo Luiz
authors.initials: AL
authors.lastname: Jacomo
authors.affiliation: USP, School of Medicine, Department of Surgery, Sao PauloSP, Brazil, Associate Professor, Division of Plastic Surgery, School of Medicine, USP, Sao Paulo-SP, Brazil. Conception and design of the study, manuscript writing, critical revision.
authors.forename: Rolf
authors.initials: R
authors.lastname: Gemperli
mesh_terms: D000818:Animals; D008297:Male; D008488:Medical Illustration; D023421:Models, Animal; D009336:Necrosis; D017208:Rats, Wistar; D012016:Reference Values; D015203:Reproducibility of Results; D012867:Skin / Q000473:pathology*; D013524:Surgical Flaps / Q000473:pathology* / Q000601:surgery; D014022:Tissue Survival