title: Factors influencing functional recovery in patients with acute ischemic stroke.
abstract: OBJECTIVE
  This study examined factors influencing functional recovery, including neurological and psychological function and activity of daily Living (ADL), in individuals hospitalized with acute ischemic stroke.
  
  
  METHODS
  A prospective observational study was undertaken in a sample of 141 hospitalized adults with acute ischemic stroke in three hospitals in metropolitan Bangkok and one in regional Thailand. Sociodemographic and clinical data were collected using a standardized questionnaire. Co-morbidity burden was assessed using the Charlson Co-morbidity Index-Modified-Thai version (CCI-T) and acute stroke care services usage using the Measurement of Acute Stroke Care Services Received form. Recovery of neurological function was measured by the National Institutes of Health Stroke Scale-Thai (NIHSS-T), and ADL function was measured by the Modified Barthel Index Measurement-Thai Version (BI-T). Psychological function was assessed using the Center for Epidemiologic Studies Depression Scale-Thai version (CES-D-T). Multivariate Logistic regression was used to analyze the predictive ability of pre-specified variables.
  
  
  RESULTS
  Receiving thrombolytic therapy was a significant predictor of functional recovery in terms of neurological (OR=4.714; P=.004) and ADL functions on the day of discharge (OR= 5.408; P=.002). Accessing acute stroke care service was the only factor predicting improved psychological function on hospital discharge (OR=1.312; P=.049).
authors.affiliation: Department of Medical Nursing, Faculty of Nursing, Mahidol University, 2 Phrannok Road, Bangkok 10700, Thailand. nssarunya@mahidol.ac.th
authors.forename: Sarunya
authors.initials: S
authors.lastname: Koositamongkol
authors.affiliation: Department of Surgical Nursing, Faculty of Nursing, Mahidol University, 2 Phrannok Road, Bangkok 10700, Thailand.
authors.forename: Siriorn
authors.initials: S
authors.lastname: Sindhu
authors.affiliation: Department of Medical Nursing, Faculty of Nursing, Mahidol University, 2 Phrannok Road, Bangkok 10700, Thailand.
authors.forename: Wanpen
authors.initials: W
authors.lastname: Pinyopasakul
authors.affiliation: Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Phrannok Road, Bangkok 10700, Thailand.
authors.forename: Yongchai
authors.initials: Y
authors.lastname: Nilanont
authors.affiliation: School of Nursing, University of Michigan, 400 North Ingalls Building, Ann Arbor, MI 48109-5482, USA.
authors.forename: Richard W
authors.initials: RW
authors.lastname: Redman
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D011237:Predictive Value of Tests; D011446:Prospective Studies; D020127:Recovery of Function; D012720:Severity of Illness Index; D012959:Socioeconomic Factors; D020521:Stroke / Q000188:drug therapy*; D000071939:Stroke Rehabilitation; D013785:Thailand; D016896:Treatment Outcome; D014481:United States
chemical_list: D005343:Fibrinolytic Agents