title: Utility of computed tomography in assessment of pulmonary hypertension secondary to biomass smoke exposure.
abstract: BACKGROUND
  The aim of this study was to investigate the feasibility of main pulmonary artery diameter quantification by thoracic computerized tomography (CT) in the diagnosis of pulmonary hypertension seconder to biomass smoke exposure.
  
  
  METHODS
  One hundred and four women subjects with biomass smoke exposure and 20 healthy women subjects were enrolled in the prospective study. The correlation between echocardiographic estimation of systolic pulmonary artery pressure and the main pulmonary artery diameter of the cases were studied.
  
  
  RESULTS
  The main pulmonary artery diameter was 26.9 ± 5.1 in the control subjects and 37.1 ± 6.4 in subjects with biomass smoke exposure. This difference was statistically significant (p<0.001). The systolic pulmonary artery pressure was 22.7 ± 12.4 in the control subjects and 57.3 ± 22 in subjects with biomass smoke exposure. This difference was statistically significant (p<0.001). Systolic pulmonary artery pressure was significantly correlated with the main pulmonary artery diameter (r=0.614, p<0.01). A receiver operating characteristic (ROC) curve analysis showed that a value of 29 mm of the main pulmonary artery diameter differentiated between pulmonary hypertension and non-pulmonary hypertension patients. The sensitivity of the measurement to diagnose pulmonary hypertension was 91% and specificity was 80%.
  
  
  CONCLUSIONS
  Our results indicate that main pulmonary artery diameter measurements by SCT may suggest presence of pulmonary hypertension in biomass smoke exposed women.
authors.affiliation: Department of Chest Disorders, Yuzuncu Yil University School of Medical Science, Van, Turkey.
authors.forename: Bunyamin
authors.initials: B
authors.lastname: Sertogullarindan
authors.affiliation: Department of Radiology, Yuzuncu Yil University, School of Medical Science, Van, Turkey.
authors.forename: Aydin
authors.initials: A
authors.lastname: Bora
authors.affiliation: Department of Radiology, Yuzuncu Yil University School of Medical Science, Van, Turkey.
authors.forename: Alpaslan
authors.initials: A
authors.lastname: Yavuz
authors.affiliation: Department of Chest Disorders, Yuzuncu Yil University, School of Medical Science, Van, Turkey.
authors.forename: Selami
authors.initials: S
authors.lastname: Ekin
authors.affiliation: Department of Chest Disorders, Yuzuncu Yil University, School of Medical Science, Van, Turkey.
authors.forename: Hulya
authors.initials: H
authors.lastname: Gunbatar
authors.affiliation: Department of Chest Disorders, Private Istanbul Hospital, Van, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Arisoy
authors.affiliation: Department of Radiology, Yuzuncu Yil University, School of Medical Science, Van, Turkey.
authors.forename: Serhat
authors.initials: S
authors.lastname: Avcu
authors.affiliation: Department of Chest Disorders, Yuzuncu Yil University, School of Medical Science, Van, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Ozbay
mesh_terms: D018533:Biomass; D001794:Blood Pressure; D004781:Environmental Exposure / Q000032:analysis*; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000503:physiopathology; D008875:Middle Aged; D011651:Pulmonary Artery / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D012372:ROC Curve; D012906:Smoke / Q000009:adverse effects*; D013599:Systole; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data*
chemical_list: D012906:Smoke