title: [The weakened form of familial adenomatosis: clinical and genetic characteristics and methods of treatment].
abstract: Clinical and genetic analysis of 24 Russian patients with attenuated form of family colon adenomatosis was undertaken. On the basis of obtained clinical and genetic data it was defined the algorithm of therapeutic measures in this group of patients--from dynamic monitoring or endoscopic polypectomy to performing extensive resections of the colon in situations associated with cancer development, an increase of the intensity of growth of polyps or an appearance of villous lesions. Some of the patients had molecular-genetics causes of a weakened form of family adenomatosis.
authors.forename: A M
authors.initials: AM
authors.lastname: Kuz'minov
authors.forename: S A
authors.initials: SA
authors.lastname: Frolov
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Sachkov
authors.forename: Iu Iu
authors.initials: IuIu
authors.lastname: Chubarov
authors.forename: N I
authors.initials: NI
authors.lastname: Pospekhova
authors.forename: A S
authors.initials: AS
authors.lastname: Tsukanov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Shelygin
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics* / Q000601:surgery*; D025601:Adenomatous Polyposis Coli Protein / Q000235:genetics*; D000328:Adult; D017677:Age Distribution; D003082:Colectomy / Q000379:methods; D003113:Colonoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012426:Russia / Q000453:epidemiology; D016896:Treatment Outcome; D057832:Watchful Waiting; D044465:White People / Q000235:genetics
chemical_list: C555337:APC protein, human; D025601:Adenomatous Polyposis Coli Protein