title: Clarifying relationships between persistent organic pollutant concentrations and age in wildlife biomonitoring: individuals, cross-sections, and the roles of lifespan and sex.
abstract: Relationships between persistent organic pollutant (POP) levels and age in wildlife biomonitoring are often interpreted as changes in contaminant burden as organisms age. However, cross-sectional body burden-age trends (CBATs) obtained from biomonitoring studies, which sample individuals of different ages at the same time, should not be confused with longitudinal body burden-age trends (LBATs) obtained by sampling the same individuals repeatedly through time. To clarify how CBATs and LBATs for wildlife species deviate from each other, and describe any impact of lifespan and sex, we used mechanistic bioaccumulation models to estimate historic longitudinal exposures of polar cod, ringed seals, beluga whales, and bowhead whales to polychlorinated biphenyl congener 153. Cross-sectional body burden-age trends were then produced by sampling resultant LBATs of successive birth cohorts at specific time points. As found previously for humans, the year of sampling relative to the year of peak environmental contamination was a critical parameter in determining male CBAT shapes. However, a similar cohort effect was not apparent for reproductive females because efficient POP loss through lactation prevented their lipids from retaining a memory of past exposure levels. Thus, lactation loss was not only responsible for the large differences between the CBATs of males and females of the same species, but also the lack of female CBAT variability through time. Cross-sectional body burden-age trend shapes varied little between species by lifespan, as long as equivalent age scales were used. However, lifespan relative to the timescale of environmental contaminant level changes did determine the extent to which CBATs resembled LBATs for males. We suggest that accounting for birth cohort and sex effects is essential when interpreting age trends in POP biomonitoring studies of long-lived species.
authors.affiliation: Department of Physical and Environmental Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Binnington
authors.forename: Frank
authors.initials: F
authors.lastname: Wania
mesh_terms: D000367:Age Factors; D000818:Animals; D000835:Animals, Wild / Q000502:physiology*; D001822:Body Burden; D003430:Cross-Sectional Studies; D004784:Environmental Monitoring / Q000379:methods*; D004785:Environmental Pollutants / Q000032:analysis* / Q000633:toxicity*; D005260:Female; D048388:Gadiformes / Q000502:physiology; D008017:Life Expectancy; D008297:Male; D008954:Models, Biological; D009930:Organic Chemicals / Q000032:analysis* / Q000633:toxicity*; D012098:Reproduction / Q000187:drug effects; D046048:Seals, Earless / Q000502:physiology; D012727:Sex Characteristics; D014907:Whales / Q000502:physiology
chemical_list: D004785:Environmental Pollutants; D009930:Organic Chemicals
keywords: Bioaccumulation; Biomonitoring; Environmental modeling; Persistent organic pollutants (POPs); Polychlorinated biphenyls (PCBs)