title: Rapid determination of quinolones in cosmetic products by ultra high performance liquid chromatography with tandem mass spectrometry.
abstract: This study developed an improved analytical method for the simultaneous quantification of 13 quinolones in cosmetics by ultra high performance liquid chromatography combined with ESI triple quadrupole MS/MS under the multiple reaction monitoring mode. The analytes were extracted and purified by using an SPE cartridge. The limits of quantification ranged from 0.03 to 3.02 μg/kg. The precision for determining the quinolones was <19.39%. The proposed method was successfully developed for the determination of quinolones in real cosmetic samples.
authors.affiliation: Laboratory of Chemistry and Physics, Hangzhou Center for Disease Control and Prevention, Hangzhou, P. R. China.
authors.forename: Shao-Ying
authors.initials: SY
authors.lastname: Liu
authors.forename: Xi-Hui
authors.initials: XH
authors.lastname: Huang
authors.forename: Xiao-Fang
authors.initials: XF
authors.lastname: Wang
authors.forename: Quan
authors.initials: Q
authors.lastname: Jin
authors.forename: Guo-Nian
authors.initials: GN
authors.lastname: Zhu
mesh_terms: D002851:Chromatography, High Pressure Liquid; D003358:Cosmetics / Q000737:chemistry*; D015363:Quinolones / Q000032:analysis*; D053719:Tandem Mass Spectrometry
chemical_list: D003358:Cosmetics; D015363:Quinolones
keywords: Cosmetics; Quinolones; Tandem mass spectrometry; Ultra high performance liquid chromatography