title: Safety and efficacy of carbon dioxide and intravascular ultrasound-guided stenting for renal artery stenosis in patients with chronic renal insufficiency.
abstract: We evaluated the feasibility, safety, and mid-term outcomes of renal artery stenting using carbon dioxide (CO₂) digital subtraction angiography and intravascular ultrasound (IVUS) for patients with renal insufficiency and significant atherosclerotic renal artery stenosis (RAS). Eighteen consecutive patients with chronic renal insufficiency underwent renal artery stenting under the guidance of CO₂ angiography and IVUS without contrast media. Renal function and blood pressure were assessed pre- and postintervention. A total of 27 de novo RAS in 18 patients (15 males; mean age: 72 ± 9 years) with renal insufficiency were treated by renal artery stenting with the combined use of the CO₂ angiography and IVUS without any procedural complications. Although the mean serum creatinine concentration preprocedure and 6 months after treatment did not change (2.7 ± 1.0-2.4 ± 1.1 mg/dL), blood pressure significantly decreased 6 months after stenting (158 ± 10-147 ± 11 mm Hg, P < .01).
authors.affiliation: Department of Internal Medicine, Cardiovascular Division, Morinomiya Hospital, Osaka, Japan daizou0524909@hotmail.com.
authors.forename: Daizo
authors.initials: D
authors.lastname: Kawasaki
authors.affiliation: Department of Internal Medicine, Cardiovascular Division, Hyogo College of Medicine, Nishinomiya, Japan.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Fujii
authors.affiliation: Department of Internal Medicine, Cardiovascular Division, Hyogo College of Medicine, Nishinomiya, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Fukunaga
authors.affiliation: Department of Internal Medicine, Cardiovascular Division, Morinomiya Hospital, Osaka, Japan.
authors.forename: Nobuhisa
authors.initials: N
authors.lastname: Fukuda
authors.affiliation: Department of Internal Medicine, Cardiovascular Division, Hyogo College of Medicine, Nishinomiya, Japan.
authors.forename: Tohru
authors.initials: T
authors.lastname: Masuyama
authors.affiliation: Department of Cardiovascular Surgery, Morinomiya Hospital, Osaka, Japan.
authors.forename: Nobukazu
authors.initials: N
authors.lastname: Ohkubo
authors.affiliation: Department of Cardiovascular Surgery, Morinomiya Hospital, Osaka, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kato
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction / Q000009:adverse effects / Q000379:methods*; D017130:Angioplasty / Q000009:adverse effects / Q000295:instrumentation*; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure; D002245:Carbon Dioxide / Q000009:adverse effects; D003287:Contrast Media / Q000009:adverse effects; D003404:Creatinine / Q000097:blood; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D015641:Radiography, Interventional / Q000009:adverse effects / Q000379:methods*; D012078:Renal Artery Obstruction / Q000097:blood / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D051436:Renal Insufficiency, Chronic / Q000097:blood / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D012307:Risk Factors; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000009:adverse effects
chemical_list: D015415:Biomarkers; D003287:Contrast Media; D002245:Carbon Dioxide; D003404:Creatinine
keywords: carbon dioxide angiography; intravascular ultrasound; renal artery stenosis