title: Chemoselective C-benzylation of unprotected anilines with benzyl alcohols using Re2O7 catalyst.
abstract: An unprecedented dehydrative C-C bond formation between unprotected anilines with benzyl alcohols is disclosed. Re2O7 catalyst (5 mol %) at elevated reaction temperature (80 °C) provided C-benzylanilines with high to excellent yields and with good chemoselectivities (over N-alkylation). A probable mechanism has been proposed based on mechanistic studies.
authors.affiliation: Department of Chemistry, Indian Institute of Science Education and Research (IISER) Bhopal , Indore By-pass Road, Bhauri, Bhopal-462066, India.
authors.forename: Rajender
authors.initials: R
authors.lastname: Nallagonda
authors.forename: Mohammad
authors.initials: M
authors.lastname: Rehan
authors.forename: Prasanta
authors.initials: P
authors.lastname: Ghorai
mesh_terms: D000478:Alkylation; D000814:Aniline Compounds / Q000737:chemistry*; D001592:Benzyl Alcohols / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D012211:Rhenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000814:Aniline Compounds; D001592:Benzyl Alcohols; C015428:perrhenate; D012211:Rhenium; C023650:aniline