title: [Preliminary report of botulinum toxin type A injection at trigger point for treatment of trigeminal neuralgia: experiences of 16 cases].
abstract: OBJECTIVE
  To investigate the effects of injection of botulium toxin type A at trigger point for treatment of patients with primary trigeminal neuralgia.
  
  
  METHODS
  Sixteen patients with primary Trigeminal Neuralgia were treated with injection of botulium toxin type A. Visual analog scores(VAS) at 1 week, 2 weeks, 1 month, 3 months and 6 months after treatment and Barrow Neurological Institute (BNI) pain evaluation criteria were utilized to measure the degree of pain. The data was analyzed with SPSS 10.0 software package.
  
  
  RESULTS
  The VAS score was 9.12±0.65 before botulium toxin type A injection while the scores were 2.8±1.36, 2.2±1.26, 1.3±1.45, 1.3±1.45 and 1.2±2.52 at 1 week, 2 weeks, 1 month,3 months and 6 months after treatment. There was significant difference in VAS compared with before treatment. VAS score was lower and stable at 1 month, 3 months and 6 months after treatment, but no significant difference was found at 1-week and 2-week after treatment. BNI evaluation results showed good therapeutic effect 1 week after treatment, while the best therapeutic effect was noted 1-3 months after treatment. 6 months later, 1 patient had recurrence and 11 patients had complete relief of pain.
  
  
  CONCLUSIONS
  Botulium toxin type A injection is an effective way for treatment of patients with primary trigeminal neuralgia.
authors.affiliation: Department of Stomatology, the Affiliated Hospital of Medical College, Qingdao University. Qingdao 266555, Shandong Province, China.E-mail:mrsy750@163.com.
authors.forename: Shuang-yi
authors.initials: SY
authors.lastname: Wang
authors.forename: Jin
authors.initials: J
authors.lastname: Yue
authors.forename: Yao-xiang
authors.initials: YX
authors.lastname: Xu
authors.forename: Ling-fa
authors.initials: LF
authors.lastname: Xue
authors.forename: Wen-lin
authors.initials: WL
authors.lastname: Xiao
authors.forename: Chun-yang
authors.initials: CY
authors.lastname: Zhang
mesh_terms: D019274:Botulinum Toxins, Type A; D006801:Humans; D010147:Pain Measurement; D016634:Radiosurgery; D016896:Treatment Outcome; D014277:Trigeminal Neuralgia; D061028:Trigger Points
chemical_list: D019274:Botulinum Toxins, Type A