title: The clinical features and long-term sequelae of invasive meningococcal disease in children.
abstract: We evaluated the outcome of invasive meningococcal disease in children <15 years of age (n = 181). Neisseria meningitidis serogroup B comprised 78% of bacterial isolates. Case fatality rate was 11.6%. In follow-up interviews (115/160 survivors, 72%), at least 1 long-term sequela was reported in 38/115 children (33%), including learning-academic difficulties (22.6%), hearing impairment (7%), neurologic (12.2%), behavioral (14.8%) and motor (10.4%) deficits.
authors.affiliation: From the *Jerusalem District Health Office, Ministry of Health; and †Braun School of Public Health and Community Medicine, Faculty of Medicine, Hebrew University and Hadassah, Jerusalem, Israel.
authors.forename: Chen
authors.initials: C
authors.lastname: Stein-Zamir
authors.forename: Hanna
authors.initials: H
authors.lastname: Shoob
authors.forename: Irina
authors.initials: I
authors.lastname: Sokolov
authors.forename: Amin
authors.initials: A
authors.lastname: Kunbar
authors.forename: Nitza
authors.initials: N
authors.lastname: Abramson
authors.forename: Deena
authors.initials: D
authors.lastname: Zimmerman
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D034381:Hearing Loss / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007859:Learning Disabilities / Q000453:epidemiology*; D008297:Male; D008569:Memory Disorders / Q000453:epidemiology*; D008585:Meningitis, Meningococcal / Q000150:complications* / Q000401:mortality / Q000473:pathology*; D009026:Mortality; D009345:Neisseria meningitidis / Q000302:isolation & purification*; D015995:Prevalence; D011596:Psychomotor Disorders / Q000453:epidemiology*