title: [Etiopathogenetic extracorporeal treatment of severe sepsis in patients after cardiac surgery].
abstract: The study deals with assessment of LPS-adsorption and haemodialysis with EMiC2-filters use in the complex treatment in cardio-surgery patients with heavy sepsis. 64 adult patients included in the study were divided into two groups. 26 patients of the main group with heavy sepsis (EEA > 0.6; procalcitonin level higher than 2 ng/ml) received LPS-adsorption and haemodialysis with EMiC2-filters. 38 patients of control group with heavy sepsis developed after surgeries on heart and vessels did not receive extracorporeal methods of treatment. Positive effect of combined extracorporeal treatment on haemodynamics, oxygenation, endotoxin activity decreasing, procalcitonin level, inflammatory and antiphlogistic cytokines level was identified Trend of 28-day survival increasing was indentified in the main group.
authors.forename: M B
authors.initials: MB
authors.lastname: Iarustovskiĭ
authors.forename: M V
authors.initials: MV
authors.lastname: Abramian
authors.forename: N P
authors.initials: NP
authors.lastname: Krotenko
authors.forename: D A
authors.initials: DA
authors.lastname: Popov
authors.forename: M G
authors.initials: MG
authors.lastname: Pliushch
authors.forename: E A
authors.initials: EA
authors.lastname: Rogal'skaia
authors.forename: E I
authors.initials: EI
authors.lastname: Nazarova
authors.forename: S L
authors.initials: SL
authors.lastname: Gordeev
mesh_terms: D006348:Cardiac Surgical Procedures; D004731:Endotoxins / Q000097:blood; D005112:Extracorporeal Circulation / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D006435:Renal Dialysis / Q000295:instrumentation / Q000379:methods; D018805:Sepsis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D012720:Severity of Illness Index; D016060:Sorption Detoxification / Q000295:instrumentation / Q000379:methods; D016896:Treatment Outcome
chemical_list: D004731:Endotoxins