title: Following the path of CCL2 from prostaglandins to periostin in lung fibrosis.
abstract: Without question, the greatest and most humbling honor of my scientific career was to learn that I was nominated for the American Thoracic Society Recognition Award for Scientific Accomplishments. On the occasion of this award, as I look back on the progress made in the last 15 years, I am pleased by the scientific insights; however, I am also saddened that we still have no internationally recognized efficacious therapy. This perspective will highlight the areas my laboratory has addressed regarding the pathogenesis of idiopathic pulmonary fibrosis in hopes of identifying new therapeutic targets.
authors.affiliation: Departments of Internal Medicine and Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan.
authors.forename: Bethany B
authors.initials: BB
authors.lastname: Moore
mesh_terms: D000818:Animals; D015815:Cell Adhesion Molecules / Q000378:metabolism*; D018932:Chemokine CCL2 / Q000378:metabolism*; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D011453:Prostaglandins / Q000378:metabolism*; D011658:Pulmonary Fibrosis / Q000378:metabolism* / Q000473:pathology*
chemical_list: D015815:Cell Adhesion Molecules; D018932:Chemokine CCL2; D011453:Prostaglandins