title: [Clinical research on cake-separated moxibustion for impaired glucose regulation].
abstract: OBJECTIVE
  To observe clinical curative effect of cake-separated moxibustion on impaired glucose regulation (IGR) and explore its action mechanism.
  
  
  METHODS
  Sixty cases were randomly divided into a simple lifestyle intervention group (control group) and a cake-separated moxibustion combined with lifestyle intervention group (observation group), 30 cases in each one. The control group was treated with lifestyle intervention. Based on lifestyle intervention, cake-separated moxibustion at Pishu (BL 20), Weishu (BL 21) and Yishu (EX-B 3) was applied to the observation group. Fast plasma glucose (FPG), two hours plasma glucose after oral glucose tolerance test (OGTT2hPG), fasting insulin (FINS), homa insulin resistance index (HOMA-IR), blood lipid, body mass index (BMI) and waist circumference (WC) were observed in the two groups before and after treatment.
  
  
  RESULTS
  After treatment, the OGTT2hPG and FPG were both decreased significantly (both P<0.05) in the two groups, compared between the two groups, the differences of FPG [(0.41 +/- 0.42) mmol/L vs (0.05 +/- 0.08)mmol/L] and OGTT2hPG [(0.85 +/- 0.53)mmol/L vs (0.17 +/- 0.19)mmol/L] were both statistically significant. There were no significant changes in FINS, HOMA-IR, blood lipid, BMI and WC in the control group before and after treatment (all P>0.05), but FINS, HOMA-IR levels, triglycerides (TG), total cholest-erol (TC), low density lipoprotein (LDL-C), BMI and WC in the observation group were decreased obviously after treatment (all P<0.05), which had statistical differences between the two groups (all P<0.05).
  
  
  CONCLUSIONS
  The cake-separated moxibustion combined with lifestyle intervention can obviously control blood glucose levels, improve insulin resistance and blood lipid levels, decrease BMI and WC.
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Sheng-Chao
authors.initials: SC
authors.lastname: Cai
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Qin
authors.forename: Wei-Hua
authors.initials: WH
authors.lastname: Yuan
authors.forename: Cheng-Gong
authors.initials: CG
authors.lastname: He
authors.forename: Yun-Yan
authors.initials: YY
authors.lastname: Cao
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005947:Glucose / Q000378:metabolism*; D018149:Glucose Intolerance / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007328:Insulin; D008297:Male; D008875:Middle Aged; D009071:Moxibustion; D055105:Waist Circumference
chemical_list: D007328:Insulin; D005947:Glucose