title: Elevated plasma 2-hydroxyglutarate in acute myeloid leukaemia: association with the IDH1 SNP rs11554137 and severe renal impairment.
authors.affiliation: Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, UK.
authors.forename: Daniel H
authors.initials: DH
authors.lastname: Wiseman
authors.forename: Helen F
authors.initials: HF
authors.lastname: Small
authors.forename: Deepti P
authors.initials: DP
authors.lastname: Wilks
authors.forename: Ian D
authors.initials: ID
authors.lastname: Waddell
authors.forename: Michael W
authors.initials: MW
authors.lastname: Dennis
authors.forename: Donald J
authors.initials: DJ
authors.lastname: Ogilvie
authors.forename: Tim C P
authors.initials: TC
authors.lastname: Somervaille
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D005977:Glutarates / Q000097:blood*; D006801:Humans; D007521:Isocitrate Dehydrogenase / Q000235:genetics*; D015470:Leukemia, Myeloid, Acute / Q000097:blood*; D009154:Mutation; D020641:Polymorphism, Single Nucleotide
chemical_list: D014408:Biomarkers, Tumor; D005977:Glutarates; C019417:alpha-hydroxyglutarate; D007521:Isocitrate Dehydrogenase; C543588:IDH1 protein, human
keywords: 2-hydroxyglutarate; acute myeloid leukaemia; isocitrate dehydrogenase; rs11554137