title: [Immunological cell therapy].
abstract: Recently there is a great advance in anti-colorectal cancer treatment. Several molecular targeting agents, mostly are antibody drugs, are playing an important role. It has recently been proven that new approaches using antibody to immunological checkpoints are effective against certain types of cancer. This is one of the reasons why cancer immunotherapy is now focused in the clinics. In this chapter, several effective immunotherapy against cancer are shown and discussed. Among several types of cancer immunotherapy, immunological cell therapy including lymphokine activated killer (LAK) cell, cytotoxic T lymphocytes (CTL), gamma delta T cell and dendritic cell therapies are reviewed. Major mechanisms that disturb cancer immunotherapy such as escape mechanisms are also discussed.
authors.affiliation: Department of Gastroenterological Oncology, International Medical Center, Saitama Medical University.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Shibata
authors.affiliation: Department of Gastroenterological Oncology, International Medical Center, Saitama Medical University.
authors.forename: Kenji
authors.initials: K
authors.lastname: Gonda
authors.affiliation: Department of Organ Regulatory Surgery, Fukushima Medical University.
authors.forename: Kensuke
authors.initials: K
authors.lastname: Kumamoto
authors.affiliation: Department of Organ Regulatory Surgery, Fukushima Medical University.
authors.forename: Seiichi
authors.initials: S
authors.lastname: Takenoshita
mesh_terms: D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D009369:Neoplasms / Q000628:therapy*