title: Translated chemical reaction networks.
abstract: Many biochemical and industrial applications involve complicated networks of simultaneously occurring chemical reactions. Under the assumption of mass action kinetics, the dynamics of these chemical reaction networks are governed by systems of polynomial ordinary differential equations. The steady states of these mass action systems have been analyzed via a variety of techniques, including stoichiometric network analysis, deficiency theory, and algebraic techniques (e.g., Gröbner bases). In this paper, we present a novel method for characterizing the steady states of mass action systems. Our method explicitly links a network's capacity to permit a particular class of steady states, called toric steady states, to topological properties of a generalized network called a translated chemical reaction network. These networks share their reaction vectors with their source network but are permitted to have different complex stoichiometries and different network topologies. We apply the results to examples drawn from the biochemical literature.
authors.affiliation: Department of Mathematics, University of Wisconsin-Madison, 480 Lincoln Dr., Madison, WI, 53706, USA, mjohnston3@wisc.edu.
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Johnston
mesh_terms: D003198:Computer Simulation; D007700:Kinetics; D008956:Models, Chemical