title: Synthesis and evaluation of novel dental monomer with branched carboxyl acid group.
abstract: To enhance the water miscibility and increase the mechanical properties of dentin adhesives, a new glycerol-based monomer with vinyl and carboxylic acid, 4-((1,3-bis(methacryloyloxy)propan-2-yl)oxy)-2-methylene-4-oxobutanoic acid (BMPMOB), was synthesized and characterized. Dentin adhesive formulations containing 2-hydroxyethyl methacrylate (HEMA), 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy) phenyl]propane (BisGMA), and BMPMOB were characterized with regard to real-time photopolymerization behavior, water sorption, dynamic mechanical analysis, and microscale three-dimensional internal morphologies and compared with HEMA/BisGMA controls. The experimental adhesive copolymers showed higher glass transition temperature and rubbery moduli, as well as improved water miscibility compared to the controls. The enhanced properties of the adhesive copolymers indicated that BMPMOB is a promising comonomer for dental restorative materials.
authors.affiliation: Bioengineering Research Center, University of Kansas, Lawrence, Kansas, 66045; School of Chemistry and Chemical Engineering, Anhui University, Hefei, China.
authors.forename: Linyong
authors.initials: L
authors.lastname: Song
authors.forename: Qiang
authors.initials: Q
authors.lastname: Ye
authors.forename: Xueping
authors.initials: X
authors.lastname: Ge
authors.forename: Anil
authors.initials: A
authors.lastname: Misra
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Laurence
authors.forename: Cynthia L
authors.initials: CL
authors.lastname: Berrie
authors.forename: Paulette
authors.initials: P
authors.lastname: Spencer
mesh_terms: D002087:Butyrates / Q000138:chemical synthesis* / Q000737:chemistry*; D003738:Dental Cements / Q000138:chemical synthesis* / Q000737:chemistry*; D008689:Methacrylates / Q000737:chemistry
chemical_list: D002087:Butyrates; D003738:Dental Cements; D008689:Methacrylates; C005044:hydroxyethyl methacrylate
keywords: crosslink polymer; dentin adhesive; dynamical mechanical property; photopolymerization; water miscibility