title: The synthesis and strecker reaction of 2-chlorotetrafluoroethanesulfinyl ketimines.
abstract: A series of 2-chlorotetrafluoroethanesulfinyl ketimines were prepared from 2-chlorotetrafluoroethanesulfinamide and ketones in high yields, and their Strecker reactions with TMSCN have been investigated. High yields and excellent diastereoselectivities were achieved in the presence of a catalytic amount of CsF under mild conditions. The six-membered chairlike models were proposed to account for the high stereoselective Strecker reaction.
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, P.R. China.
authors.forename: Kai
authors.initials: K
authors.lastname: Yang
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Liu
authors.forename: Jin-Tao
authors.initials: JT
authors.lastname: Liu