title: Recurrent progressive anterior segment fibrosis syndrome following a descemet-stripping endothelial keratoplasty in an infant with congenital aniridia.
abstract: Progressive anterior segment fibrosis syndrome (ASFS), after intraocular surgery in older children (≥ 9 years) and adults with congenital aniridia, is described in the literature. In this report, we describe an unique case of ASFS in an infant with congenital aniridia following a combined trabeculotomy-ectomy and its recurrence after a descemet stripping endothelial keratoplasty. The ophthalmologists should be well aware of this entity and warn the parents about its possibilities. Use of immunomodulators or prolonged anti-inflammatory therapy may be considered to prevent its occurrence.
authors.affiliation: Department of Pediatric Ophthalmology and Adult Strabismus, Department of Cornea Services, Aditya Jyot Eye Hospital, Wadala, Mumbai, Maharashtra, India.
authors.forename: Mihir
authors.initials: M
authors.lastname: Kothari
authors.forename: Kavita
authors.initials: K
authors.lastname: Rao
authors.forename: Samita
authors.initials: S
authors.lastname: Moolani
mesh_terms: D015783:Aniridia / Q000601:surgery*; D000869:Anterior Eye Segment / Q000473:pathology*; D057111:Descemet Stripping Endothelial Keratoplasty / Q000009:adverse effects*; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D005355:Fibrosis / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology*; D012008:Recurrence; D013577:Syndrome