title: Challenges in the management of infections due to carbapenem-resistant Enterobacteriaceae.
abstract: Carbapenem-resistant Enterobacteriaceae (CRE) infections are increasing and are associated with considerable morbidity and mortality. Members of the Emerging Infections Network treating CRE encountered difficulties in obtaining laboratory results and struggled with limited treatment options. In addition, many treated patients experienced an alarming degree of drug toxicity from CRE therapies.
authors.affiliation: Minneapolis Veterans Affairs Health Care System, Minneapolis, Minnesota.
authors.forename: Dimitri M
authors.initials: DM
authors.lastname: Drekonja
authors.forename: Susan E
authors.initials: SE
authors.lastname: Beekmann
authors.forename: Sean
authors.initials: S
authors.lastname: Elliott
authors.forename: Deepa
authors.initials: D
authors.lastname: Mukundan
authors.forename: Hari
authors.initials: H
authors.lastname: Polenakovik
authors.forename: Marnie E
authors.initials: ME
authors.lastname: Rosenthal
authors.forename: Pranita D
authors.initials: PD
authors.lastname: Tamma
authors.forename: Philip M
authors.initials: PM
authors.lastname: Polgreen
authors.forename: Scott J
authors.initials: SJ
authors.lastname: Weissman
mesh_terms: D000328:Adult; D015780:Carbapenems / Q000494:pharmacology / Q000627:therapeutic use*; D024881:Drug Resistance, Bacterial; D004755:Enterobacteriaceae / Q000187:drug effects*; D004756:Enterobacteriaceae Infections / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D011795:Surveys and Questionnaires
chemical_list: D015780:Carbapenems