title: An unusual response to intravenous sedation: a case report.
abstract: Midazolam is a benzodiazepine commonly used for conscious sedation in dentistry.This paper reports a state of unconsciousness in a 14-year-old girl after administration of midazolam sedation for dental treatment, which was not reversible with flumazenil.The patient remained in an Intensive Care Unit for two days, unresponsive to any stimulus. A range of tests were inconclusive, but the diagnosis of an unusual reaction to midazolam was made. The patient fully recovered and was discharged from hospital after 6 days. A referral to a sleeping disorder clinic was made to investigate the patient's sleeping patterns.This paper highlights the importance of sedation being provided by an appropriately trained team.
authors.forename: Liège
authors.initials: L
authors.lastname: Lourenço-Matharu
authors.forename: Pritesh
authors.initials: P
authors.lastname: Raval
mesh_terms: D000293:Adolescent; D016292:Procedural Sedation / Q000009:adverse effects*; D055191:Delayed Emergence from Anesthesia / Q000139:chemically induced*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000009:adverse effects*; D007262:Infusions, Intravenous / Q000009:adverse effects; D008874:Midazolam / Q000008:administration & dosage / Q000009:adverse effects*; D014081:Tooth Extraction; D014474:Unconsciousness / Q000139:chemically induced*
chemical_list: D006993:Hypnotics and Sedatives; D008874:Midazolam