title: The burden of disease due to tuberculosis in the state of Santa Catarina, Brazil.
abstract: OBJECTIVE
  To estimate the burden of disease due to tuberculosis in the state of Santa Catarina, Brazil, in 2009.
  
  
  METHODS
  This was an epidemiological study with an ecological design. Data on tuberculosis incidence and mortality were collected from specific Brazilian National Ministry of Health databases. The burden of disease due to tuberculosis was based on the calculation of disability-adjusted life years (DALYs). The DALYs were estimated by adding the years of life lost (YLLs) and years lived with disability (YLDs). Absolute values were transformed into rates per 100,000 population. The rates were calculated by gender, age group, and health care macroregion.
  
  
  RESULTS
  The burden of disease due to tuberculosis was 5,644.27 DALYs (92.25 DALYs/100,000 population), YLLs and YLDs respectively accounting for 78.77% and 21.23% of that total. The highest rates were found in males in the 30-44 and 45-59 year age brackets, although that was not true in every health care macroregion. Overall, the highest estimated burden was in the Planalto Norte macroregion (179.56 DALYs/100,000 population), followed by the Nordeste macroregion (167.07 DALYs/100,000 population).
  
  
  CONCLUSIONS
  In the majority of the health care macroregions of Santa Catarina, the burden of disease due to tuberculosis was concentrated in adult males, the level of that concentration varying among the various macroregions.
authors.affiliation: University of Southern Santa Catarina, Tubarão, Brazil, Master's Student. Graduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Brazil.
authors.forename: Glênio César Nunes
authors.initials: GC
authors.lastname: Ferrer
authors.affiliation: University of Southern Santa Catarina, Tubarão, Brazil, Professor. Graduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Brazil.
authors.forename: Rosemeri Maurici
authors.initials: RM
authors.lastname: da Silva
authors.affiliation: Santa Rosa de Lima City Hall, Santa Rosa de Lima, Brazil, Nurse, Santa Rosa de Lima City Hall, Santa Rosa de Lima, Brazil.
authors.forename: Kelian Tenfen
authors.initials: KT
authors.lastname: Ferrer
authors.affiliation: University of Southern Santa Catarina, Tubarão, Brazil, Professor. Graduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Brazil.
authors.forename: Jefferson
authors.initials: J
authors.lastname: Traebert
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D006233:Persons with Disabilities; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D014376:Tuberculosis / Q000453:epidemiology* / Q000401:mortality; D055815:Young Adult