title: Limb regeneration in salamanders and digital tip regeneration in experimental mice: implications for the hand surgeon.
abstract: Several lessons and observations from limb regeneration in animals could open new insights to direct related research in the field of hand surgery. This article briefly reviews the biology of limb regeneration in salamanders and experimental mice, with special emphasis on implications for hand surgery.
  
  
  METHODS
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authors.affiliation: Division of Plastic Surgery, King Saud University, Riyadh, Saudi Arabia moqattan@hotmail.com.
authors.forename: M M
authors.initials: MM
authors.lastname: Al-Qattan
authors.affiliation: Division of Plastic Surgery, King Saud University, Riyadh, Saudi Arabia.
authors.forename: A M
authors.initials: AM
authors.lastname: Al-Qattan
authors.affiliation: College of Medicine Research Center, King Saud University, Riyadh, Saudi Arabia.
authors.forename: D A
authors.initials: DA
authors.lastname: Al-Maged Ahmed
authors.affiliation: College of Medicine Research Center, King Saud University, Riyadh, Saudi Arabia.
authors.forename: M M
authors.initials: MM
authors.lastname: Abd Al-Wahed
authors.affiliation: College of Medicine Research Center, King Saud University, Riyadh, Saudi Arabia.
authors.forename: M K
authors.initials: MK
authors.lastname: Shier
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D055415:Bone Morphogenetic Protein 4 / Q000502:physiology; D047109:Fetal Development / Q000502:physiology; D005383:Finger Injuries / Q000503:physiopathology / Q000601:surgery; D005552:Forelimb / Q000502:physiology*; D006614:Hindlimb / Q000502:physiology*; D018398:Homeodomain Proteins / Q000502:physiology; D006801:Humans; D018878:Limb Buds / Q000187:drug effects / Q000502:physiology; D051379:Mice / Q000502:physiology*; D012038:Regeneration / Q000187:drug effects / Q000502:physiology*; D013045:Species Specificity; D057170:Translational Research, Biomedical; D014212:Tretinoin / Q000494:pharmacology; D014562:Caudata / Q000502:physiology*
chemical_list: C525810:Bmp4 protein, mouse; D055415:Bone Morphogenetic Protein 4; D018398:Homeodomain Proteins; D014212:Tretinoin
keywords: hand; mice; nAG; regeneration; salamander