title: [Effect of Scutellaria baicalensis root extract on cytogenetic damage induced by paclitaxel and cisplatin in mice].
abstract: The effect of root extract of Baikal skullcap (Scutellaria baicalensis) cultivated in vitro, on the gene structure of CBA/CaLac mice bone marrow cells damaged by anticancer drugs paclitaxel and cisplatin has been studied. It is established that the root extract exhibits gene protective property upon both single and chronic administration.
authors.forename: O V
authors.initials: OV
authors.lastname: Neupokoeva
authors.forename: O L
authors.initials: OL
authors.lastname: Voronova
authors.forename: A A
authors.initials: AA
authors.lastname: Churin
authors.forename: N I
authors.initials: NI
authors.lastname: Suslov
authors.forename: I V
authors.initials: IV
authors.lastname: Shilova
authors.forename: I N
authors.initials: IN
authors.lastname: Kuzovkina
mesh_terms: D059786:Abnormal Karyotype / Q000139:chemically induced / Q000187:drug effects; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects* / Q000494:pharmacology; D001854:Bone Marrow Cells / Q000378:metabolism* / Q000473:pathology; D002945:Cisplatin / Q000009:adverse effects* / Q000494:pharmacology; D005260:Female; D008297:Male; D051379:Mice; D017239:Paclitaxel / Q000009:adverse effects* / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry*; D031364:Scutellaria baicalensis / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; C499814:Scutellaria baicalensis extract; D017239:Paclitaxel; D002945:Cisplatin