title: Can treatment for polycystic ovarian disease induce ovarian tumour? A case report.
abstract: Polycystic ovarian disease in adolescents is not uncommon. Usually underlying ovarian tumours can cause hirsutism and ovulation. A 15-year-old girl presented with infrequent cycles and hirsutism. Her baseline evaluation ruled out ovarian tumour and other endocrinological problems. She was treated with insulin sensitizers and hormone treatment. After more than a year of treatment she developed a large ovarian tumour which turned out to be a juvenile granulose cell tumour at laparotomy a year after treatment with insulin sensitizers. The authors recommend continued surveillance of ovaries of adolescent girls undergoing treatment for polycystic ovarian disease to monitor for formation of ovarian tumours.
authors.affiliation: Professor, Department of Obstetrics and Gynecology, JIPMER , Puducherry, India .
authors.forename: Gowri
authors.initials: G
authors.lastname: Dorairajan
authors.affiliation: Associate Professor. Department of Obstetrics and Gynecology, Indira Gandhi Medical College , RI, Puducherry, India .
authors.forename: N Hima
authors.initials: NH
authors.lastname: Bindu
authors.affiliation: Professor, Department of Pathology, Indira Gandhi Medical College , RI, Puducherry, India .
authors.forename: Ramachandra V
authors.initials: RV
authors.lastname: Bhat
keywords: Hirsutism, Anovulation; Juvenile granulose cell tumour; Polycystic ovarian disease