title: Potential clinical exploitation of the radiation-induced DNA damage response.
authors.affiliation: Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, UK.
authors.forename: R P
authors.initials: RP
authors.lastname: Symonds
authors.affiliation: Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, UK. Electronic address: gdj2@le.ac.uk.
authors.forename: G D
authors.initials: GD
authors.lastname: Jones
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology; D001260:Ataxia Telangiectasia / Q000188:drug therapy / Q000235:genetics; D064007:Ataxia Telangiectasia Mutated Proteins / Q000037:antagonists & inhibitors; D000071877:Checkpoint Kinase 1; D064447:Checkpoint Kinase 2 / Q000037:antagonists & inhibitors; D059248:Chemoradiotherapy; D004247:DNA / Q000528:radiation effects*; D004249:DNA Damage / Q000187:drug effects*; D015507:Drugs, Investigational / Q000494:pharmacology; D018773:Genes, erbB-1 / Q000187:drug effects / Q000528:radiation effects; D006801:Humans; D011494:Protein Kinases / Q000187:drug effects; D011832:Radiation Injuries / Q000517:prevention & control*; D011853:Radiobiology / Q000639:trends; D042461:Vascular Endothelial Growth Factor A / Q000187:drug effects / Q000528:radiation effects
chemical_list: D000970:Antineoplastic Agents; D015507:Drugs, Investigational; D042461:Vascular Endothelial Growth Factor A; D004247:DNA; D011494:Protein Kinases; D064447:Checkpoint Kinase 2; C576324:ATM protein, human; C576597:ATR protein, human; D064007:Ataxia Telangiectasia Mutated Proteins; C578634:CHEK2 protein, human; D000071877:Checkpoint Kinase 1