title: Hyper IgE syndrome.
abstract: Hyper IgE syndrome (HIES) is a rare disorder characterized by eczema, recurrent infections of the skin and lungs, typically with Staphylococcus aureus, Candida albicans and certain viruses, and elevated levels of serum IgE. Other clinical manifestations include characteristic facies (prominent forehead, broad nasal bridge and facial asymmetry), chronic eczematous dermatitis, retained primary dentition, recurrent pathological fractures, hyper-extensibility and scoliosis. The central nervous system (CNS) involvement in HIES has been rarely reported. Here we presented a case of HIES with rare associations of epilepsy in a young patient to raise awareness for this disorder.
authors.affiliation: Department of Dermatology, Second Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Dang
authors.affiliation: Department of Dermatology, Second Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
authors.forename: Jianwen
authors.initials: J
authors.lastname: Ren
authors.affiliation: Department of Dermatology, Second Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Guo
authors.affiliation: Department of Dermatology, Second Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
authors.forename: Songmei
authors.initials: S
authors.lastname: Geng
keywords: Hyper IgE syndrome; eczema; epilepsy