title: Seroprevalence of T. cruzi infection in blood donors and Chagas cardiomyopathy in patients from the coal mining region of Coahuila, Mexico.
abstract: OBJECTIVE
  Chagas disease is considered a worldwide emerging disease; it is endemic in Mexico and the state of Coahuila and is considered of little relevance. The objective of this study was to determine the seroprevalence of T. cruzi infection in blood donors and Chagas cardiomyopathy in patients from the coal mining region of Coahuila, Mexico.
  
  
  METHODS
  Epidemiological, exploratory and prospective study in a general hospital during the period January to June 2011.
  
  
  METHODS
  We performed laboratory tests ELISA and indirect hemagglutination in three groups of individuals: 1) asymptomatic voluntary blood donors, 2) patients hospitalized in the cardiology department and 3) patients with dilated cardiomyopathy.
  
  
  RESULTS
  There were three levels of seroprevalence: 0.31% in asymptomatic individuals, 1.25% in cardiac patients and in patients with dilated cardiomyopathy in 21.14%.
  
  
  CONCLUSIONS
  In spite of having detected autochthonous cases of Chagas disease, its importance to local public health remains to be established as well as the details of the dynamics of transmission so that the study is still in progress.
authors.affiliation: Doctoral Student. Hospital General de Zona No 24, Instituto Mexicano del Seguro Social, Nueva RositaCoahuila, México, Doctoral Student. Hospital General de Zona No 24, Instituto Mexicano del Seguro Social, Nueva Rosita, Coahuila, México.
authors.forename: José Gerardo
authors.initials: JG
authors.lastname: Martínez-Tovar
authors.affiliation: Laboratorio de Entomología Médica, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Medical Entomologist. Universidad Autónoma de Nuevo León. Facultad de Ciencias Biológicas. Laboratorio de Entomología Médica.
authors.forename: Eduardo A
authors.initials: EA
authors.lastname: Rebollar-Téllez
authors.affiliation: Laboratorio de Entomología Médica, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Medical Entomologist. Universidad Autónoma de Nuevo León. Facultad de Ciencias Biológicas. Laboratorio de Entomología Médica.
authors.forename: Ildefonso
authors.initials: I
authors.lastname: Fernández Salas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000913:Antibodies, Protozoan / Q000097:blood*; D001782:Blood Donors / Q000706:statistics & numerical data*; D002598:Chagas Cardiomyopathy / Q000175:diagnosis / Q000453:epidemiology; D014355:Chagas Disease / Q000175:diagnosis / Q000453:epidemiology*; D003032:Coal Mining; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D011446:Prospective Studies; D016036:Seroepidemiologic Studies; D014349:Trypanosoma cruzi / Q000276:immunology*; D055815:Young Adult
chemical_list: D000913:Antibodies, Protozoan