title: Comparison of Tc-99m GSA scintigraphy and CT volumetry for evaluation in portal vein embolization.
abstract: OBJECTIVE
  To determine the correlation of the rate of change of each future remnant liver (FRL) before and after portal vein embolization (PVE), by CT volumetry and Tc-99m galactosyl human serum albumin scintigraphy (GSA scintigraphy).
  
  
  METHODS
  From December 2007 to July 2012, ten patients underwent PVE before hepatic resection. CT volumetry and GSA scintigraphy were performed before and after PVE. The FRL was divided at Cantlie's line for CT volumetry, and volume change rates before and after PVE were calculated. The maximum removal rate (Rmax) was calculated using a radiopharmacokinetic model in GSA scintigraphy. The FRL Rmax change rates before and after PVE were calculated. The correlation between the volume change rates and the Rmax change rates was analyzed.
  
  
  RESULTS
  The FRL volume change rate was 1.28 ± 0.26 (mean ± SD); the FRL hypertrophied in all patients significantly (p = 0.005). The FRL Rmax change rate was 1.66 ± 0.75; excluding one patient, there was significant FRL Rmax increase (p = 0.022). Although both increased significantly, no correlation between the volume change rate and the Rmax change rate was observed.
  
  
  CONCLUSIONS
  No correlation was observed between the FRL volume rate and the Rmax rate.
authors.affiliation: Department of Radiology, Kansai Medical University , Osaka , Japan.
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Kono
authors.forename: Shuji
authors.initials: S
authors.lastname: Kariya
authors.forename: Atsushi
authors.initials: A
authors.lastname: Komemushi
authors.forename: Miyuki
authors.initials: M
authors.lastname: Nakatani
authors.forename: Rie Yagi
authors.initials: RY
authors.lastname: Yoshida
authors.forename: Satoshi
authors.initials: S
authors.lastname: Suzuki
authors.forename: Sung Kil
authors.initials: SK
authors.lastname: Ha-Kawa
authors.forename: Keita
authors.initials: K
authors.lastname: Utsunomiya
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ueno
authors.forename: Sohei
authors.initials: S
authors.lastname: Satoi
authors.forename: Masaki
authors.initials: M
authors.lastname: Kaibori
authors.forename: Masanori
authors.initials: M
authors.lastname: Kon
authors.forename: Noboru
authors.initials: N
authors.lastname: Tanigawa
mesh_terms: D000368:Aged; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery; D008111:Liver Function Tests; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D011169:Portal Vein; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D013668:Technetium Tc 99m Aggregated Albumin; D016284:Technetium Tc 99m Pentetate
chemical_list: D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; C070561:technetium Tc 99m DTPA-galactosyl-human serum albumin; D016284:Technetium Tc 99m Pentetate
keywords: CT volumetry; GSA scintigraphy; PVE; Rmax