title: Weekly cisplatin may reverse liver dysfunction and jaundice caused by diffuse liver metastases of solid tumors.
abstract: Few data are available on patient management in jaundice caused by liver metastases of solid tumors (nonbreast and noncolon origin). We report the first patient series consecutively treated with cisplatin weekly in patients with severe jaundice and liver failure due to underlying metastatic neoplasms. In 4 out of 8 cases, liver function tests were reversed and jaundice disappeared, permitting subsequent standard chemotherapy. The other 4 patients died 3 to 5 weeks after admission, illustrating the extent and severity of the underlying neoplasm.
authors.affiliation: Dept of Medical Oncology, Regionaal Ziekenhuis Sint Maria, Halle, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Gabrovska
authors.affiliation: Dept of Medical Oncology, Regionaal Ziekenhuis Sint Maria, Halle, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Geurs
authors.affiliation: Dept of Gastroenterology, Pneumology, Regionaal Ziekenhuis Sint Maria, Halle, Belgium.
authors.forename: S
authors.initials: S
authors.lastname: Ponette
authors.affiliation: Dept of Gastroenterology, Pneumology, Regionaal Ziekenhuis Sint Maria, Halle, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: Ponette
authors.affiliation: Dept of Gastroenterology, Pneumology, Regionaal Ziekenhuis Sint Maria, Halle, Belgium.
authors.forename: K
authors.initials: K
authors.lastname: Bulte
authors.affiliation: Dept of Pneumology, Regionaal Ziekenhuis Sint Maria, Halle, Belgium.
authors.forename: L
authors.initials: L
authors.lastname: Derveaux
authors.affiliation: Dept of Surgery, Regionaal Ziekenhuis Sint Maria, Halle, Belgium.
authors.forename: I
authors.initials: I
authors.lastname: Kempeneers
keywords: chemotherapy; cisplatin; jaundice; liver failure; metastases