title: Enantioselective synthesis of planar chiral ferrocenes via Pd(0)-catalyzed intramolecular direct C-H bond arylation.
abstract: A highly efficient synthesis of planar chiral ferrocenes by enantioselective Pd(0)-catalyzed direct C-H arylation from readily available starting materials under mild reaction conditions was developed (up to 99% yield, 99% ee). The products can be easily transformed to the highly efficient planar ferrocene ligands, which have demonstrated high efficiency in Pd-catalyzed asymmetric allylic alkylation and amination reactions.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Lu, Shanghai 200032, P. R. China.
authors.forename: De-Wei
authors.initials: DW
authors.lastname: Gao
authors.forename: Qin
authors.initials: Q
authors.lastname: Yin
authors.forename: Qing
authors.initials: Q
authors.lastname: Gu
authors.forename: Shu-Li
authors.initials: SL
authors.lastname: You
mesh_terms: D000478:Alkylation; D000498:Allyl Compounds / Q000737:chemistry; D000586:Amination; D002384:Catalysis; D005296:Ferrous Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D000075163:Metallocenes; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000498:Allyl Compounds; D005296:Ferrous Compounds; D000075163:Metallocenes; D010165:Palladium; C004998:ferrocene