title: Oxidative cross-coupling of allenyl ketones and organoboronic acids: expeditious synthesis of highly substituted furans.
abstract: Allenyl ketones are employed as coupling partners in palladium-catalyzed oxidative cross-coupling reactions with organoboronic acids. This reaction constitutes an efficient methodology for the synthesis of highly substituted furan derivatives. Palladium-carbene migratory insertion is proposed as the key step in this transformation.
authors.affiliation: Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871 (China).
authors.forename: Ying
authors.initials: Y
authors.lastname: Xia
authors.forename: Yamu
authors.initials: Y
authors.lastname: Xia
authors.forename: Rui
authors.initials: R
authors.lastname: Ge
authors.forename: Zhen
authors.initials: Z
authors.lastname: Liu
authors.forename: Qing
authors.initials: Q
authors.lastname: Xiao
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jianbo
authors.initials: J
authors.lastname: Wang
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*
chemical_list: D001897:Boronic Acids; D005663:Furans; D007659:Ketones; D010165:Palladium; C039281:furan
keywords: allenes; carbenes; cross-coupling; furans; palladium