title: Potassium N-iodo p-toluenesulfonamide (TsNIK, Iodamine-T): a new reagent for the oxidation of hydrazones to diazo compounds.
abstract: A new reagent for the oxidation of hydrazones to diazo compounds is described. N-Iodo p-toluenesulfonamide (TsNIK, iodamine-T) allows the preparation of α-diazoesters, α-diazoamides, α-diazoketones and α-diazophosphonates in good yield and in high purity after a simple extractive work-up. α-Diazoesters were also obtained in high yield from the corresponding ketones through a one-pot process of hydrazone formation/oxidation.
authors.affiliation: School of Chemistry, University of Nottingham, Nottingham NG7 2RD (UK), Fax: (+44) 115-951-3564.
authors.forename: Simon M
authors.initials: SM
authors.lastname: Nicolle
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Moody
keywords: diazo compounds; hydrazones; iodine; oxidation