title: Stimulated penetrating keratoplasty using real-time virtual intraoperative surgical optical coherence tomography.
abstract: An intraoperative surgical microscope is an essential tool in a neuro- or ophthalmological surgical environment. Yet, it has an inherent limitation to classify subsurface information because it only provides the surface images. To compensate for and assist in this problem, combining the surgical microscope with optical coherence tomography (OCT) has been adapted. We developed a real-time virtual intraoperative surgical OCT (VISOCT) system by adapting a spectral-domain OCT scanner with a commercial surgical microscope. Thanks to our custom-made beam splitting and image display subsystems, the OCT images and microscopic images are simultaneously visualized through an ocular lens or the eyepiece of the microscope. This improvement helps surgeons to focus on the operation without distraction to view OCT images on another separate display. Moreover, displaying the OCT live images on the eyepiece helps surgeon's depth perception during the surgeries. Finally, we successfully processed stimulated penetrating keratoplasty in live rabbits. We believe that these technical achievements are crucial to enhance the usability of the VISOCT system in a real surgical operating condition.
authors.affiliation: Pohang University of Science and Technology (POSTECH), Departments of Electrical Engineering and Creative IT Engineering, Pohang 790-784, Republic of Korea.
authors.forename: Changho
authors.initials: C
authors.lastname: Lee
authors.affiliation: Kyungpook National University, School of Electronics Engineering, Daegu 702-701, Republic of Korea.
authors.forename: Kyungun
authors.initials: K
authors.lastname: Kim
authors.affiliation: Kyungpook National University, School of Electronics Engineering, Daegu 702-701, Republic of Korea.
authors.forename: Seunghoon
authors.initials: S
authors.lastname: Han
authors.affiliation: Kyungpook National University, School of Electronics Engineering, Daegu 702-701, Republic of Korea.
authors.forename: Sehui
authors.initials: S
authors.lastname: Kim
authors.affiliation: Metro Eye Center, Daegu 700-733, Republic of Korea.
authors.forename: Jun Hoon
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Kyungpook National University Hospital, Department of Ophthalmology, College of Medicine, Daegu 700-721, Republic of Korea.
authors.forename: Hong Kyun
authors.initials: HK
authors.lastname: Kim
authors.affiliation: Pohang University of Science and Technology (POSTECH), Departments of Electrical Engineering and Creative IT Engineering, Pohang 790-784, Republic of Korea.
authors.forename: Chulhong
authors.initials: C
authors.lastname: Kim
authors.affiliation: Ulsan National Institute of Science and Technology, School of Nano-Bioscience & Chemical Engineering, Ulsan 689-798, Republic of Korea.
authors.forename: Woonggyu
authors.initials: W
authors.lastname: Jung
authors.affiliation: Kyungpook National University, School of Electronics Engineering, Daegu 702-701, Republic of Korea.
authors.forename: Jeehyun
authors.initials: J
authors.lastname: Kim
mesh_terms: D000818:Animals; D015948:Keratoplasty, Penetrating / Q000295:instrumentation* / Q000379:methods*; D008853:Microscopy / Q000295:instrumentation* / Q000379:methods*; D011817:Rabbits; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods*