title: Allylic oxidation of alkenes catalyzed by a copper-aluminum mixed oxide.
abstract: A strategy for the allylic oxidation of cyclic alkenes with a copper-aluminum mixed oxide as catalyst is presented. The reaction involves the treatment of an alkene with a carboxylic acid employing tert-butyl hydroperoxide as the oxidant. In all cases, the corresponding allylic esters are obtained. When L-proline is employed, the allylic alcohol or ketone is obtained. The oxidation of cyclohexene and valencene has been optimized by design of experiments (DoE) statistical methodology.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz , 11510 Puerto Real, Cádiz, Spain.
authors.forename: Ana Leticia
authors.initials: AL
authors.lastname: García-Cabeza
authors.forename: Rubén
authors.initials: R
authors.lastname: Marín-Barrios
authors.forename: F Javier
authors.initials: FJ
authors.lastname: Moreno-Dorado
authors.forename: María J
authors.initials: MJ
authors.lastname: Ortega
authors.forename: Guillermo M
authors.initials: GM
authors.lastname: Massanet
authors.forename: Francisco M
authors.initials: FM
authors.lastname: Guerra